# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Pkinase PF00069.25 CDJ80068.1 - 4e-60 203.4 0.0 8.2e-60 202.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ80068.1 - 1.3e-36 126.2 0.0 2.2e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 CDJ80068.1 - 1.5e-21 76.3 16.9 6.3e-10 39.0 2.5 3.5 3 0 0 3 3 3 3 Hr1 repeat Kinase-like PF14531.6 CDJ80068.1 - 2.2e-05 23.9 0.0 4.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF4618 PF15397.6 CDJ80068.1 - 0.086 12.2 6.9 0.21 11.0 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) TolA_bind_tri PF16331.5 CDJ80068.1 - 0.12 12.4 2.4 7.5 6.7 0.6 2.7 2 0 0 2 2 2 0 TolA binding protein trimerisation PALP PF00291.25 CDJ80069.1 - 5.2e-66 223.0 0.5 6.3e-66 222.8 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 CDJ80069.1 - 0.041 13.9 0.3 0.11 12.5 0.1 1.9 2 1 0 2 2 2 0 Zinc-binding dehydrogenase PID_2 PF14719.6 CDJ80070.1 - 1.9e-72 242.9 0.1 2.7e-72 242.4 0.1 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) VPS9 PF02204.18 CDJ80071.1 - 3.7e-24 84.9 0.0 1.7e-23 82.8 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RasGAP PF00616.19 CDJ80071.1 - 6.2e-13 48.9 0.0 1.4e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase Y1_Tnp PF01797.16 CDJ80071.1 - 0.069 13.3 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Transposase IS200 like UBX PF00789.20 CDJ80074.1 - 5.4e-07 29.7 0.0 1.1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 UBX domain MULE PF10551.9 CDJ80077.1 - 4.1e-06 27.1 0.0 7.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain zinc_ribbon_15 PF17032.5 CDJ80078.1 - 0.25 12.1 5.2 0.3 11.9 1.9 2.2 2 1 0 2 2 2 0 zinc-ribbon family IF4E PF01652.18 CDJ80079.1 - 7.7e-43 146.0 0.1 1e-42 145.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E HNOBA PF07701.14 CDJ80080.1 - 3.8e-57 193.3 0.2 6.2e-57 192.6 0.2 1.3 1 0 0 1 1 1 1 Heme NO binding associated Guanylate_cyc PF00211.20 CDJ80080.1 - 5.9e-57 192.2 0.0 9.1e-57 191.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOB PF07700.15 CDJ80080.1 - 1.5e-26 93.3 0.0 3.1e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 Haem-NO-binding Glyco_tran_28_C PF04101.16 CDJ80080.1 - 0.078 13.0 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain IIGP PF05049.13 CDJ80081.1 - 9.3e-12 44.7 0.0 4.1e-07 29.4 0.0 2.2 2 0 0 2 2 2 2 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 CDJ80081.1 - 3.4e-09 37.3 0.0 0.00099 19.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CDJ80081.1 - 3.2e-08 33.8 2.6 2.1e-05 24.5 0.0 3.0 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 CDJ80081.1 - 4.8e-08 33.1 0.1 0.0028 17.7 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 CDJ80081.1 - 5e-08 32.6 0.5 0.0006 19.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 CDJ80081.1 - 1.8e-07 31.9 0.0 0.0008 20.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CDJ80081.1 - 8.6e-07 29.0 0.1 0.047 13.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 CDJ80081.1 - 3.2e-05 23.8 0.4 0.034 13.9 0.0 2.5 3 0 0 3 3 3 2 AAA ATPase domain Dynamin_N PF00350.23 CDJ80081.1 - 0.00019 21.5 0.2 0.036 14.1 0.0 2.5 2 0 0 2 2 2 1 Dynamin family SMC_N PF02463.19 CDJ80081.1 - 0.011 15.2 0.7 2.5 7.5 0.2 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain FeoB_N PF02421.18 CDJ80081.1 - 0.027 14.0 0.4 3.2 7.3 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 CDJ80081.1 - 0.059 13.6 0.0 16 5.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 CDJ80081.1 - 0.11 11.5 1.6 3.4 6.6 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 CDJ80081.1 - 0.14 12.5 0.6 29 5.1 0.0 2.9 3 0 0 3 3 3 0 RNA helicase AAA_28 PF13521.6 CDJ80081.1 - 0.14 12.4 0.1 25 5.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain Septin PF00735.18 CDJ80081.1 - 0.23 10.7 0.1 5 6.3 0.0 2.4 3 0 0 3 3 3 0 Septin COesterase PF00135.28 CDJ80083.1 - 1.5e-130 436.5 0.0 2e-130 436.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Pkinase PF00069.25 CDJ80085.1 - 7.1e-14 51.8 0.1 1.1e-10 41.4 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ80085.1 - 1.3e-09 37.7 0.2 1.5e-07 31.0 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Ion_trans_2 PF07885.16 CDJ80086.1 - 5.7e-34 115.9 18.2 3.1e-17 62.3 0.9 2.8 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CDJ80086.1 - 4.4e-06 26.1 10.1 0.0013 18.0 0.5 2.2 2 0 0 2 2 2 2 Ion transport protein CDI PF02234.19 CDJ80086.1 - 0.21 11.8 0.4 0.44 10.8 0.4 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor BTB_2 PF02214.22 CDJ80088.1 - 2.7e-08 34.0 0.0 5.3e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain UBA_4 PF14555.6 CDJ80089.1 - 6.5e-11 41.9 0.0 1.8e-10 40.5 0.1 1.8 2 0 0 2 2 2 1 UBA-like domain UBX PF00789.20 CDJ80089.1 - 0.0012 19.0 0.0 0.0031 17.7 0.0 1.7 1 0 0 1 1 1 1 UBX domain Myc_N PF01056.18 CDJ80089.1 - 0.2 11.5 9.7 1 9.2 0.1 2.1 2 0 0 2 2 2 0 Myc amino-terminal region RasGAP PF00616.19 CDJ80089.1 - 0.27 10.9 5.2 0.52 10.0 5.2 1.5 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase TERB2 PF15101.6 CDJ80089.1 - 0.47 10.5 8.2 11 6.0 8.6 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Exonuc_VII_L PF02601.15 CDJ80089.1 - 2.9 7.4 10.0 4.3 6.8 10.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit PA26 PF04636.13 CDJ80089.1 - 3.2 6.6 8.4 5.3 5.9 8.4 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CAF1 PF04857.20 CDJ80089.1 - 6.9 5.7 10.5 12 4.9 10.5 1.3 1 0 0 1 1 1 0 CAF1 family ribonuclease AAA_11 PF13086.6 CDJ80089.1 - 8.9 6.0 11.2 17 5.1 11.2 1.4 1 0 0 1 1 1 0 AAA domain YAF2_RYBP PF17219.3 CDJ80090.1 - 5.8e-05 22.6 0.2 0.00011 21.7 0.2 1.5 1 0 0 1 1 1 1 Yaf2/RYBP C-terminal binding motif AAA_5 PF07728.14 CDJ80091.1 - 7.6e-100 330.5 0.0 6.2e-38 129.9 0.0 3.7 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDJ80091.1 - 1.4e-06 28.8 8.2 0.84 10.0 0.3 5.4 4 2 1 5 5 4 2 AAA ATPase domain AAA_2 PF07724.14 CDJ80091.1 - 6.5e-06 26.4 0.1 0.036 14.2 0.0 3.8 4 0 0 4 4 4 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDJ80091.1 - 0.00029 21.1 5.3 0.94 9.8 0.1 5.0 3 2 0 3 3 3 2 AAA domain AAA_7 PF12775.7 CDJ80091.1 - 0.0013 18.2 0.0 1.4 8.4 0.0 3.5 4 0 0 4 4 4 1 P-loop containing dynein motor region VWA_2 PF13519.6 CDJ80091.1 - 0.0024 18.5 0.0 0.012 16.3 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain AAA PF00004.29 CDJ80091.1 - 0.0032 17.9 0.0 1.9 8.9 0.0 3.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CDJ80091.1 - 0.013 15.8 0.0 0.036 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CDJ80091.1 - 0.024 14.0 0.5 2.5 7.4 0.0 3.3 3 1 0 3 3 3 0 Magnesium chelatase, subunit ChlI Roc PF08477.13 CDJ80091.1 - 0.027 14.7 0.1 2 8.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 CDJ80091.1 - 0.1 13.1 0.0 4.3 7.9 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.6 CDJ80091.1 - 0.11 12.9 0.2 23 5.3 0.0 3.1 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.6 CDJ80091.1 - 0.11 13.0 0.2 0.78 10.3 0.0 2.5 3 0 0 3 3 2 0 AAA domain Miff PF05644.11 CDJ80092.1 - 4.9e-14 52.6 0.6 3.1e-08 33.6 0.0 2.3 1 1 1 2 2 2 2 Mitochondrial and peroxisomal fission factor Mff DUF5082 PF16888.5 CDJ80092.1 - 0.16 12.3 0.0 0.22 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) ANF_receptor PF01094.28 CDJ80095.1 - 3.4e-49 167.8 0.0 4.5e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 CDJ80095.1 - 9.1e-48 163.0 11.4 1.5e-47 162.4 11.4 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Csm1_N PF18504.1 CDJ80095.1 - 0.013 15.8 2.1 0.028 14.8 2.1 1.5 1 0 0 1 1 1 0 Csm1 N-terminal domain PRKG1_interact PF15898.5 CDJ80095.1 - 0.025 15.5 2.0 0.058 14.3 2.0 1.6 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain SHE3 PF17078.5 CDJ80095.1 - 0.084 12.6 3.2 0.15 11.8 3.2 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 BRCA-2_OB3 PF09104.10 CDJ80095.1 - 0.14 11.8 2.3 5.9 6.5 0.8 2.4 2 0 0 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 TolA_bind_tri PF16331.5 CDJ80095.1 - 0.65 10.1 7.4 3.6 7.7 3.4 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation DivIC PF04977.15 CDJ80095.1 - 1.9 8.3 4.0 5 7.0 4.0 1.7 1 0 0 1 1 1 0 Septum formation initiator CBS PF00571.28 CDJ80096.1 - 5.2e-19 68.4 11.3 1e-06 29.1 0.0 5.2 4 1 1 5 5 5 4 CBS domain GYF PF02213.16 CDJ80098.1 - 0.049 13.3 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 GYF domain Y2_Tnp PF04986.13 CDJ80098.1 - 0.32 11.0 2.0 0.5 10.4 2.0 1.4 1 0 0 1 1 1 0 Putative transposase PA26 PF04636.13 CDJ80098.1 - 1.2 7.9 9.6 1.8 7.4 9.6 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Med19 PF10278.9 CDJ80098.1 - 2.1 8.3 14.7 3.8 7.4 14.7 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 FapA PF03961.13 CDJ80098.1 - 3 6.4 14.0 4.6 5.7 14.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A NARP1 PF12569.8 CDJ80098.1 - 3.1 6.6 17.8 4.8 6.0 17.8 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Toxin_2 PF00451.19 CDJ80098.1 - 4 7.8 10.1 18 5.7 0.3 2.4 2 0 0 2 2 2 0 Scorpion short toxin, BmKK2 DUF4746 PF15928.5 CDJ80098.1 - 4.3 6.7 17.4 6.1 6.2 17.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) S-methyl_trans PF02574.16 CDJ80099.1 - 2.3e-54 185.0 0.0 2.6e-54 184.8 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Ribosomal_S16 PF00886.19 CDJ80099.1 - 0.024 14.7 0.0 0.43 10.7 0.0 2.2 1 1 0 1 1 1 0 Ribosomal protein S16 Gag_p30 PF02093.16 CDJ80099.1 - 0.042 13.4 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 Gag P30 core shell protein SAM_1 PF00536.30 CDJ80100.1 - 7.6e-33 112.8 0.1 4.6e-15 55.8 0.0 2.3 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CDJ80100.1 - 5.7e-22 77.6 0.0 7.7e-13 48.3 0.0 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) Caskin-tail PF16632.5 CDJ80100.1 - 3.2e-05 24.2 0.0 0.00012 22.5 0.0 2.0 1 0 0 1 1 1 1 C-terminal region of Caskin NCD1 PF04904.13 CDJ80100.1 - 0.044 13.8 0.0 5.2 7.1 0.0 3.0 3 0 0 3 3 3 0 NAB conserved region 1 (NCD1) Ank_2 PF12796.7 CDJ80101.1 - 2.8e-30 104.7 2.6 3.3e-10 40.4 0.4 4.0 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ80101.1 - 1.2e-29 102.0 7.6 6.4e-10 39.1 0.1 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDJ80101.1 - 2.4e-28 98.2 0.4 4.6e-08 33.5 0.0 5.0 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ80101.1 - 3e-26 88.6 0.5 6e-05 23.1 0.1 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 CDJ80101.1 - 6.5e-25 86.4 3.8 0.00036 20.9 0.1 7.1 7 1 1 8 8 8 6 Ankyrin repeat 7TM_GPCR_Srt PF10321.9 CDJ80102.1 - 0.033 13.2 21.0 0.047 12.7 21.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt TMCO5 PF14992.6 CDJ80102.1 - 0.28 10.7 0.5 0.61 9.6 0.5 1.6 1 0 0 1 1 1 0 TMCO5 family Peptidase_M1 PF01433.20 CDJ80104.1 - 1.5e-50 171.8 0.4 2.8e-50 170.9 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 CDJ80104.1 - 1.7e-34 119.8 0.0 2.6e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Pkinase PF00069.25 CDJ80105.1 - 1.5e-76 257.3 0.0 1.7e-76 257.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ80105.1 - 6.6e-35 120.6 0.0 1.7e-34 119.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ80105.1 - 2e-05 23.7 0.4 4.1e-05 22.7 0.4 1.4 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CDJ80105.1 - 0.0038 16.9 0.1 0.0061 16.2 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CDJ80105.1 - 0.0042 17.1 0.1 0.0096 15.9 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family YukC PF10140.9 CDJ80105.1 - 0.014 14.2 0.1 0.019 13.8 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Seadorna_VP7 PF07387.11 CDJ80105.1 - 0.064 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 CDJ80105.1 - 0.13 11.9 0.1 7.8 6.1 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CDJ80105.1 - 0.14 11.5 0.3 0.31 10.4 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_30 PF13604.6 CDJ80106.1 - 0.00021 21.1 0.2 0.00028 20.7 0.2 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CDJ80106.1 - 0.0062 16.6 0.2 0.012 15.6 0.2 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CDJ80106.1 - 0.014 15.7 0.0 0.016 15.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 CDJ80106.1 - 0.021 14.6 0.1 0.041 13.7 0.1 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Helicase_RecD PF05127.14 CDJ80106.1 - 0.025 14.4 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Helicase UvrD-helicase PF00580.21 CDJ80106.1 - 0.035 13.6 1.4 0.052 13.1 0.5 1.6 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_11 PF13086.6 CDJ80106.1 - 0.036 13.9 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain ARL2_Bind_BART PF11527.8 CDJ80106.1 - 0.15 12.2 0.5 1.1 9.3 0.2 2.1 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART Apolipoprotein PF01442.18 CDJ80107.1 - 2.1e-29 102.7 123.2 1.6e-06 28.2 17.4 9.0 1 1 7 9 9 9 8 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 CDJ80107.1 - 1.3e-19 70.5 140.6 0.016 15.8 2.8 20.1 1 1 19 21 21 21 14 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 CDJ80107.1 - 1.7e-18 67.1 77.2 0.00036 20.6 2.8 12.0 2 1 10 13 13 13 10 Apolipophorin-III precursor (apoLp-III) YtxH PF12732.7 CDJ80107.1 - 6.4e-13 49.0 174.6 14 6.3 9.0 22.3 2 2 3 5 5 2 1 YtxH-like protein Prominin PF05478.11 CDJ80107.1 - 3.8e-09 35.1 21.0 0.025 12.6 0.0 7.0 2 1 6 8 8 8 4 Prominin Sec34 PF04136.15 CDJ80107.1 - 2.3e-08 34.1 22.6 0.6 10.0 0.1 9.2 7 3 1 9 9 9 5 Sec34-like family DUF1932 PF09130.11 CDJ80107.1 - 8.2e-05 22.5 33.4 1.5 8.8 0.6 9.4 7 2 2 9 9 9 4 Domain of unknown function (DUF1932) Stanniocalcin PF03298.13 CDJ80107.1 - 0.044 13.1 0.0 0.14 11.5 0.0 1.8 1 0 0 1 1 1 0 Stanniocalcin family UPF0147 PF03685.13 CDJ80107.1 - 0.19 11.8 15.7 50 4.0 0.1 7.9 7 0 0 7 7 7 0 Uncharacterised protein family (UPF0147) Entericidin PF08085.11 CDJ80107.1 - 0.32 11.1 27.1 20 5.4 0.2 10.5 9 0 0 9 9 9 0 Entericidin EcnA/B family ParE_toxin PF05016.15 CDJ80107.1 - 3.3 8.4 26.5 28 5.4 0.1 8.9 3 2 5 8 8 8 0 ParE toxin of type II toxin-antitoxin system, parDE DUF4406 PF14359.6 CDJ80107.1 - 9.1 6.8 28.2 2.2 8.8 0.3 9.5 9 3 3 13 13 13 0 Domain of unknown function (DUF4406) LEA_4 PF02987.16 CDJ80108.1 - 0.0015 18.6 4.5 0.0017 18.4 1.0 2.2 1 1 0 2 2 2 1 Late embryogenesis abundant protein YtxH PF12732.7 CDJ80108.1 - 0.028 14.9 0.4 0.039 14.5 0.4 1.2 1 0 0 1 1 1 0 YtxH-like protein LEA_4 PF02987.16 CDJ80110.1 - 0.0015 18.5 1.2 0.0015 18.5 1.2 2.2 1 1 0 1 1 1 1 Late embryogenesis abundant protein YtxH PF12732.7 CDJ80110.1 - 0.023 15.2 0.9 0.034 14.7 0.9 1.3 1 0 0 1 1 1 0 YtxH-like protein CCDC50_N PF15295.6 CDJ80111.1 - 0.0099 16.0 2.7 0.013 15.6 2.7 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 50 N-terminus YtxH PF12732.7 CDJ80111.1 - 0.016 15.7 2.7 0.022 15.3 2.7 1.2 1 0 0 1 1 1 0 YtxH-like protein DUF1823 PF08853.11 CDJ80111.1 - 0.11 12.6 0.1 0.13 12.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1823) YtxH PF12732.7 CDJ80112.1 - 0.0046 17.5 1.6 0.006 17.1 1.6 1.1 1 0 0 1 1 1 1 YtxH-like protein HHH_8 PF14716.6 CDJ80112.1 - 0.081 13.3 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix domain Motile_Sperm PF00635.26 CDJ80114.1 - 1.7e-11 44.0 0.0 2e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF2027 PF09640.10 CDJ80114.1 - 0.067 12.8 0.0 0.073 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) SCVP PF17619.2 CDJ80117.1 - 7.2e-11 42.8 0.4 2.4e-07 31.5 0.1 2.3 1 1 1 2 2 2 2 Secreted clade V proteins RVT_3 PF13456.6 CDJ80117.1 - 0.035 13.9 0.0 0.69 9.7 0.0 2.2 2 0 0 2 2 2 0 Reverse transcriptase-like SCVP PF17619.2 CDJ80118.1 - 1.8e-10 41.5 0.0 2.6e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Secreted clade V proteins SCVP PF17619.2 CDJ80119.1 - 1.9e-09 38.3 0.0 2.5e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Secreted clade V proteins SCVP PF17619.2 CDJ80120.1 - 1.5e-05 25.7 0.1 2.2e-05 25.3 0.1 1.2 1 0 0 1 1 1 1 Secreted clade V proteins MOZ_SAS PF01853.18 CDJ80121.1 - 9.7e-76 253.4 0.2 1.4e-75 252.9 0.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CDJ80121.1 - 1e-19 69.9 2.6 4e-19 68.0 2.6 2.0 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 CDJ80121.1 - 0.11 12.9 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PA26 PF04636.13 CDJ80121.1 - 0.13 11.2 3.5 0.31 9.9 3.5 1.6 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) EMC3_TMCO1 PF01956.16 CDJ80121.1 - 0.15 11.8 3.2 0.28 10.9 3.2 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like FUSC PF04632.12 CDJ80121.1 - 0.3 9.6 4.4 0.52 8.8 4.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family 7tm_1 PF00001.21 CDJ80122.1 - 4.8e-72 242.4 0.4 5.9e-72 242.2 0.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ80122.1 - 2.6e-07 30.3 1.5 2.6e-07 30.3 1.5 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 CDJ80122.1 - 2.9e-07 30.1 1.5 0.00056 19.4 0.4 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 CDJ80122.1 - 2.8e-05 23.9 3.7 2.8e-05 23.9 3.7 2.3 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 CDJ80122.1 - 5.2e-05 23.1 7.1 0.00047 20.0 5.0 2.6 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srbc PF10316.9 CDJ80122.1 - 1 8.8 8.9 0.066 12.7 3.4 1.7 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srbc T2SSF PF00482.23 CDJ80122.1 - 4.1 7.4 5.2 13 5.8 0.1 2.8 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F Amidinotransf PF02274.17 CDJ80124.1 - 1.2e-27 96.9 0.0 4.6e-26 91.7 0.0 2.0 1 1 0 1 1 1 1 Amidinotransferase HMG_box PF00505.19 CDJ80125.1 - 5.6e-25 87.5 3.2 1.2e-24 86.5 3.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ80125.1 - 3.2e-09 37.3 1.0 3.2e-09 37.3 1.0 1.8 2 0 0 2 2 2 1 HMG-box domain DM13 PF10517.9 CDJ80126.1 - 3.8e-10 40.3 0.1 5.2e-09 36.6 0.0 2.6 3 0 0 3 3 3 1 Electron transfer DM13 RHH_7 PF16777.5 CDJ80126.1 - 0.12 12.7 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator, RHH-like, CopG DM13 PF10517.9 CDJ80127.1 - 5.4e-13 49.4 0.0 1.6e-08 35.1 0.0 3.5 3 0 0 3 3 3 2 Electron transfer DM13 ATG_C PF09333.11 CDJ80128.1 - 1.7e-16 60.3 0.0 4.4e-16 59.0 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 CDJ80128.1 - 9e-16 58.0 0.1 2.6e-15 56.6 0.1 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG2_CAD PF13329.6 CDJ80128.1 - 0.079 12.7 0.1 0.25 11.1 0.1 1.8 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif BAAT_C PF08840.11 CDJ80129.1 - 3.4e-37 128.4 0.0 4.7e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Bile_Hydr_Trans PF04775.14 CDJ80129.1 - 3.3e-21 75.7 0.0 4.9e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region Peptidase_S15 PF02129.18 CDJ80129.1 - 5.9e-06 26.1 0.0 2e-05 24.3 0.0 1.7 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 CDJ80129.1 - 9.8e-06 25.2 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 CDJ80129.1 - 0.0089 15.6 0.0 0.02 14.4 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 CDJ80129.1 - 0.072 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_M20 PF01546.28 CDJ80130.1 - 4.3e-33 114.8 0.0 6.6e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CDJ80130.1 - 5.3e-13 48.8 0.0 1.3e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.14 CDJ80130.1 - 0.00018 20.6 0.0 0.00063 18.8 0.0 1.8 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 CDJ80130.1 - 0.012 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 NAD_binding_4 PF07993.12 CDJ80131.1 - 6.9e-78 261.4 0.0 9.1e-78 261.0 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 CDJ80131.1 - 9.1e-32 109.2 1.2 2.5e-31 107.7 1.2 1.8 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 CDJ80131.1 - 3.8e-07 29.8 0.1 1.8e-06 27.6 0.1 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CDJ80131.1 - 7e-06 25.2 5.9 3.4e-05 23.0 2.3 3.1 2 2 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CDJ80131.1 - 1.9e-05 23.9 0.0 3.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 CDJ80131.1 - 3.9e-05 23.2 0.0 0.00054 19.5 0.0 2.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CDJ80131.1 - 0.0022 17.1 0.3 0.035 13.2 0.1 2.6 3 0 0 3 3 3 1 RmlD substrate binding domain Phage_holin_3_6 PF07332.11 CDJ80132.1 - 0.015 15.3 4.6 0.017 15.1 4.6 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III ABC2_membrane_3 PF12698.7 CDJ80132.1 - 0.05 12.7 6.6 0.056 12.6 6.6 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2207 PF09972.9 CDJ80132.1 - 0.58 8.9 3.2 0.65 8.7 3.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DHHC PF01529.20 CDJ80132.1 - 3.5 7.7 6.5 1.2 9.3 3.6 1.6 1 1 1 2 2 2 0 DHHC palmitoyltransferase DUF4773 PF15998.5 CDJ80135.1 - 2.3e-25 89.4 1.7 4.2e-25 88.5 1.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4773) Pkinase_Tyr PF07714.17 CDJ80136.1 - 5.9e-87 291.2 0.0 8.7e-87 290.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ80136.1 - 4e-35 121.5 0.1 1.4e-27 96.7 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.6 CDJ80136.1 - 2.2e-33 114.7 9.0 3.3e-10 40.4 0.0 7.4 6 1 0 6 6 6 5 Immunoglobulin domain I-set PF07679.16 CDJ80136.1 - 2.3e-32 110.9 7.1 8.9e-13 48.1 0.0 6.5 7 0 0 7 7 6 5 Immunoglobulin I-set domain ig PF00047.25 CDJ80136.1 - 1.9e-25 88.9 7.4 3.8e-06 27.0 0.2 7.0 7 0 0 7 7 7 4 Immunoglobulin domain Ig_2 PF13895.6 CDJ80136.1 - 5.5e-23 81.1 9.1 1.8e-07 31.4 0.2 7.2 7 1 0 7 7 7 5 Immunoglobulin domain V-set PF07686.17 CDJ80136.1 - 4.5e-19 68.6 4.6 7e-05 23.0 0.1 7.2 5 2 2 7 7 7 4 Immunoglobulin V-set domain Ig_6 PF18452.1 CDJ80136.1 - 6.2e-07 28.9 0.0 2.1 8.0 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin domain Ig_4 PF16680.5 CDJ80136.1 - 0.00022 21.4 7.1 3.6 7.9 0.1 5.8 7 0 0 7 7 7 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 CDJ80136.1 - 0.0011 19.0 0.1 6.5 6.9 0.0 4.3 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain LapA_dom PF06305.11 CDJ80136.1 - 0.0067 16.2 0.7 0.014 15.2 0.7 1.4 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Pkinase_fungal PF17667.1 CDJ80136.1 - 0.092 11.5 0.0 0.2 10.4 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Collagen PF01391.18 CDJ80137.1 - 1.9e-22 78.7 82.0 1.7e-08 34.1 32.4 4.3 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Actin PF00022.19 CDJ80138.1 - 1.7e-152 507.7 0.0 5.6e-152 506.1 0.0 1.6 1 1 0 1 1 1 1 Actin I-EGF_1 PF18372.1 CDJ80140.1 - 3.6e-08 33.3 33.5 1.9e-06 27.9 10.3 5.2 5 1 0 5 5 5 3 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 CDJ80140.1 - 0.002 18.4 14.7 0.002 18.4 14.7 6.6 4 3 3 7 7 7 3 EGF-like domain DUF5562 PF17717.1 CDJ80141.1 - 0.0018 18.3 1.4 0.0023 17.9 0.0 1.7 1 1 1 2 2 2 1 Family of unknown function (DUF5562) DUF1003 PF06210.11 CDJ80141.1 - 8.2 6.6 6.6 19 5.4 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) CC PF04942.14 CDJ80142.1 - 0.1 12.8 3.9 0.1 12.8 3.9 5.0 6 0 0 6 6 6 0 CC domain Lustrin_cystein PF14625.6 CDJ80143.1 - 0.01 16.2 15.3 0.013 15.9 0.3 2.7 3 0 0 3 3 3 0 Lustrin, cysteine-rich repeated domain EB PF01683.18 CDJ80144.1 - 0.0001 22.5 16.5 0.0001 22.5 16.5 3.0 3 1 2 5 5 5 3 EB module MFS_1 PF07690.16 CDJ80145.1 - 3.9e-45 154.3 35.6 1.1e-44 152.8 27.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CDJ80145.1 - 1.3e-05 24.0 8.2 1.3e-05 24.0 8.2 3.4 2 1 2 4 4 4 1 MFS/sugar transport protein MFS_4 PF06779.14 CDJ80145.1 - 0.0038 16.6 3.2 0.0038 16.6 3.2 2.4 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MttA_Hcf106 PF02416.16 CDJ80145.1 - 0.2 11.0 0.1 0.42 10.0 0.1 1.5 1 0 0 1 1 1 0 mttA/Hcf106 family zf-LYAR PF08790.11 CDJ80145.1 - 7.9 6.5 6.8 10 6.1 0.9 3.1 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger ACBP PF00887.19 CDJ80146.1 - 4e-29 100.7 0.0 5e-29 100.3 0.0 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein LIM PF00412.22 CDJ80147.1 - 8.5e-57 189.2 67.8 2.3e-14 53.3 5.9 5.1 5 0 0 5 5 5 5 LIM domain Flavodoxin_4 PF12682.7 CDJ80147.1 - 0.14 11.8 0.1 0.57 9.9 0.0 1.9 2 0 0 2 2 2 0 Flavodoxin DUF1364 PF07102.12 CDJ80147.1 - 0.22 11.4 16.8 0.55 10.1 1.3 4.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1364) Laminin_G_1 PF00054.23 CDJ80148.1 - 2e-10 41.0 0.0 3.4e-08 33.8 0.0 2.6 2 1 1 3 3 3 2 Laminin G domain Laminin_G_2 PF02210.24 CDJ80148.1 - 4e-07 30.6 0.0 2.9e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 Laminin G domain Laminin_G_3 PF13385.6 CDJ80148.1 - 0.00016 21.9 0.0 0.0018 18.4 0.0 2.0 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Kazal_2 PF07648.15 CDJ80150.1 - 2.1e-56 187.8 91.8 7.1e-11 42.1 7.1 9.1 9 0 0 9 9 9 7 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CDJ80150.1 - 1.5e-39 133.7 88.8 2.7e-08 33.7 8.4 8.7 8 1 0 8 8 8 7 Kazal-type serine protease inhibitor domain Laminin_EGF PF00053.24 CDJ80150.1 - 1.1e-12 47.9 33.5 2.2e-09 37.3 10.4 10.8 7 2 4 11 11 11 2 Laminin EGF domain FOLN PF09289.10 CDJ80150.1 - 0.009 16.2 1.0 0.009 16.2 1.0 8.0 6 0 0 6 6 6 1 Follistatin/Osteonectin-like EGF domain SLBP_RNA_bind PF15247.6 CDJ80152.1 - 3.8e-22 78.2 4.2 9.7e-22 76.9 4.2 1.7 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain Homeodomain PF00046.29 CDJ80153.1 - 1.3e-21 76.2 5.1 2.1e-21 75.5 5.1 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ80153.1 - 0.0024 17.7 0.1 0.0058 16.5 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 CDJ80153.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_26 PF13443.6 CDJ80153.1 - 0.18 12.3 0.1 0.32 11.5 0.1 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Homez PF11569.8 CDJ80153.1 - 0.34 10.4 0.1 0.34 10.4 0.1 2.2 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez GN3L_Grn1 PF08701.11 CDJ80154.1 - 1.1e-17 63.9 26.4 1.1e-17 63.9 26.4 3.3 3 0 0 3 3 3 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 CDJ80154.1 - 2.4e-16 59.8 0.8 3.6e-14 52.8 0.0 2.8 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ80154.1 - 2.6e-13 49.8 0.0 2.1e-08 33.8 0.0 2.6 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 CDJ80154.1 - 1.9e-06 27.6 2.1 0.00015 21.4 0.0 3.5 4 0 0 4 4 4 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CDJ80154.1 - 0.00014 21.9 9.0 0.06 13.4 0.1 4.2 2 2 2 4 4 4 2 Dynamin family RsgA_GTPase PF03193.16 CDJ80154.1 - 0.00015 21.7 0.1 0.33 10.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase cobW PF02492.19 CDJ80154.1 - 0.00017 21.2 0.1 0.085 12.4 0.0 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 CDJ80154.1 - 0.39 9.7 2.2 0.51 9.3 0.0 2.3 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Cyto_heme_lyase PF01265.17 CDJ80154.1 - 0.51 9.9 6.0 1.1 8.8 6.0 1.5 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase Anp1 PF03452.14 CDJ80155.1 - 2.2e-05 24.0 0.7 0.00025 20.5 0.1 2.3 2 0 0 2 2 2 1 Anp1 Glyco_tranf_2_3 PF13641.6 CDJ80155.1 - 0.00024 21.1 0.0 0.046 13.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 2OG-FeII_Oxy_3 PF13640.6 CDJ80155.1 - 0.0003 21.6 0.0 0.00076 20.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_tranf_2_4 PF13704.6 CDJ80155.1 - 0.0055 17.2 0.3 1.6 9.3 0.0 3.3 4 0 0 4 4 4 1 Glycosyl transferase family 2 GIDA PF01134.22 CDJ80156.1 - 4.8e-143 477.0 0.0 8.2e-143 476.2 0.0 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 CDJ80156.1 - 6.3e-65 219.3 0.1 9e-65 218.8 0.1 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_binding_2 PF00890.24 CDJ80156.1 - 7.7e-08 31.8 4.7 1.3e-05 24.5 1.5 2.5 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 CDJ80156.1 - 6.9e-07 28.8 1.9 1.3e-06 27.9 1.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CDJ80156.1 - 1.8e-06 27.6 0.4 3.3e-06 26.7 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CDJ80156.1 - 0.0011 18.1 3.8 0.009 15.1 3.8 2.2 1 1 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 CDJ80156.1 - 0.0021 17.4 0.0 0.0021 17.4 0.0 2.3 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 CDJ80156.1 - 0.0066 15.2 1.1 0.0066 15.2 1.1 3.4 4 0 0 4 4 4 1 HI0933-like protein Pyr_redox_3 PF13738.6 CDJ80156.1 - 0.007 15.7 0.0 0.084 12.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDJ80156.1 - 0.008 16.7 0.2 0.025 15.2 0.2 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CDJ80156.1 - 0.17 10.7 1.5 3.1 6.5 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase LppA PF16708.5 CDJ80156.1 - 0.18 11.7 0.2 0.42 10.5 0.0 1.7 2 0 0 2 2 2 0 Lipoprotein confined to pathogenic Mycobacterium DAO PF01266.24 CDJ80156.1 - 0.75 9.3 4.0 10 5.6 0.9 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase TPR_2 PF07719.17 CDJ80157.1 - 1.8e-15 55.7 0.0 0.00023 21.0 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ80157.1 - 1.4e-13 50.0 0.0 5.8e-06 25.9 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ80157.1 - 2.5e-13 49.5 0.0 1.7e-07 30.8 0.0 3.3 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 CDJ80157.1 - 5e-10 38.8 0.0 0.00027 20.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ80157.1 - 2.1e-09 37.5 0.0 5.3e-07 29.8 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ80157.1 - 3.6e-07 30.1 0.0 5.6e-06 26.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ80157.1 - 3.3e-05 23.6 0.9 0.0041 17.0 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ80157.1 - 5.4e-05 23.6 0.5 1.9 9.3 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ80157.1 - 0.00013 22.6 0.2 0.066 13.9 0.0 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ80157.1 - 0.00026 21.5 0.3 0.47 11.4 0.1 3.3 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ80157.1 - 0.00038 20.6 0.1 1.9 8.7 0.1 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat DUF3856 PF12968.7 CDJ80157.1 - 0.024 14.7 0.6 4.9 7.2 0.0 2.7 1 1 2 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_7 PF13176.6 CDJ80157.1 - 0.071 13.2 0.1 1.3 9.2 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat SNF PF00209.18 CDJ80158.1 - 2.7e-94 316.7 24.2 3.6e-94 316.3 24.2 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Popeye PF04831.13 CDJ80158.1 - 1 9.5 4.6 1.1 9.5 0.4 2.7 2 0 0 2 2 2 0 Popeye protein conserved region SNF PF00209.18 CDJ80160.1 - 2.8e-72 244.1 15.0 4e-72 243.6 15.0 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Glutaminase PF04960.15 CDJ80161.1 - 9.9e-116 385.9 0.0 1.4e-115 385.4 0.0 1.2 1 0 0 1 1 1 1 Glutaminase EF-hand_14 PF17959.1 CDJ80161.1 - 4.5e-27 94.2 0.8 8.5e-27 93.3 0.8 1.5 1 0 0 1 1 1 1 EF-hand domain Ank_2 PF12796.7 CDJ80161.1 - 4.4e-14 52.8 0.0 1.2e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ80161.1 - 1.2e-11 44.9 0.2 9.8e-07 29.2 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ80161.1 - 4.6e-06 26.8 0.7 0.023 15.0 0.1 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 CDJ80161.1 - 8.1e-06 26.1 0.1 0.007 16.8 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CDJ80161.1 - 5e-05 23.4 0.1 0.076 13.6 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat zf-RING_2 PF13639.6 CDJ80162.1 - 8.1e-13 48.5 6.3 1.4e-12 47.7 6.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CDJ80162.1 - 1.3e-11 44.0 3.9 1.3e-11 44.0 3.9 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CDJ80162.1 - 6.2e-08 32.4 6.8 1e-07 31.6 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ80162.1 - 1.3e-07 31.3 4.4 2.3e-07 30.6 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ80162.1 - 2.3e-07 30.7 3.5 6.6e-07 29.3 3.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDJ80162.1 - 1.3e-06 28.2 3.6 2.2e-06 27.5 3.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CDJ80162.1 - 1.7e-06 27.8 1.7 2.6e-06 27.2 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDJ80162.1 - 1.6e-05 25.1 9.0 0.00014 22.1 9.0 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CDJ80162.1 - 0.0016 18.3 3.8 0.0029 17.4 3.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 CDJ80162.1 - 0.0083 16.3 6.7 0.086 13.0 6.7 2.5 1 1 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 CDJ80162.1 - 0.023 14.3 3.6 0.044 13.4 3.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 CDJ80162.1 - 0.11 12.7 2.5 0.29 11.3 2.5 1.7 1 1 0 1 1 1 0 RING-variant domain zf-ANAPC11 PF12861.7 CDJ80162.1 - 0.14 12.3 6.8 2.6 8.2 7.0 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 CDJ80162.1 - 0.52 10.2 4.9 1.2 9.1 4.9 1.6 1 1 0 1 1 1 0 PHD-finger zf-C3H2C3 PF17122.5 CDJ80162.1 - 0.56 10.3 3.3 1.5 8.9 3.3 1.7 1 1 0 1 1 1 0 Zinc-finger zf-C3HC4_4 PF15227.6 CDJ80162.1 - 0.66 10.2 5.2 1.9 8.7 5.2 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 CDJ80162.1 - 1.1 9.1 4.5 1.8 8.4 4.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ABC_tran PF00005.27 CDJ80163.1 - 1.4e-10 41.8 0.0 2.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CDJ80163.1 - 3.1e-05 23.5 0.1 4e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain 3HCDH_N PF02737.18 CDJ80163.1 - 0.028 14.3 0.1 0.031 14.2 0.1 1.0 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SbcCD_C PF13558.6 CDJ80163.1 - 0.1 12.8 0.6 2.1 8.6 0.6 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Germane PF10646.9 CDJ80163.1 - 0.11 13.2 0.0 0.14 12.9 0.0 1.3 1 0 0 1 1 1 0 Sporulation and spore germination Exo_endo_phos PF03372.23 CDJ80164.1 - 0.002 17.7 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CDJ80164.1 - 0.013 15.4 0.4 0.061 13.2 0.0 2.4 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase Exo_endo_phos_2 PF14529.6 CDJ80165.1 - 0.0015 18.4 0.0 0.021 14.7 0.0 2.5 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase Scaffolding_pro PF11418.8 CDJ80165.1 - 0.023 15.3 0.1 0.05 14.1 0.1 1.6 1 0 0 1 1 1 0 Phi29 scaffolding protein DUF1677 PF07911.13 CDJ80165.1 - 0.057 13.8 0.3 0.11 12.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) Exo_endo_phos PF03372.23 CDJ80165.1 - 0.12 11.9 0.8 1.1 8.7 0.0 2.5 3 0 0 3 3 3 0 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 CDJ80166.1 - 2.1e-16 60.1 0.0 3.7e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FCH PF00611.23 CDJ80167.1 - 3.9e-15 55.9 0.7 3.9e-15 55.9 0.7 1.8 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain RVT_1 PF00078.27 CDJ80168.1 - 1.9e-20 73.4 0.0 2.3e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MIP-T3_C PF17749.1 CDJ80169.1 - 0.00042 20.3 3.5 0.00042 20.3 3.5 2.1 3 0 0 3 3 3 1 Microtubule-binding protein MIP-T3 C-terminal region SKA1 PF07160.12 CDJ80169.1 - 0.03 14.2 6.4 0.049 13.5 6.4 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF2031 PF09592.10 CDJ80169.1 - 0.45 10.0 8.1 0.69 9.4 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) Ribosomal_L21p PF00829.21 CDJ80169.1 - 5.9 7.2 7.0 4.8 7.5 1.2 2.2 1 1 1 2 2 2 0 Ribosomal prokaryotic L21 protein Collagen PF01391.18 CDJ80170.1 - 1.1e-17 63.6 68.5 4.6e-09 35.9 35.4 2.7 2 2 0 2 2 2 2 Collagen triple helix repeat (20 copies) TMEM154 PF15102.6 CDJ80172.1 - 2.4e-06 27.5 2.3 7.3e-06 25.9 2.3 1.9 1 0 0 1 1 1 1 TMEM154 protein family AJAP1_PANP_C PF15298.6 CDJ80172.1 - 0.00019 21.7 5.9 0.00019 21.7 5.9 1.6 2 0 0 2 2 2 1 AJAP1/PANP C-terminus Protocadherin PF08374.11 CDJ80172.1 - 0.0096 15.9 2.0 0.0097 15.9 0.7 1.7 2 0 0 2 2 2 1 Protocadherin Peptidase_M56 PF05569.11 CDJ80172.1 - 0.011 15.0 0.2 0.016 14.4 0.2 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 GAPT PF11770.8 CDJ80172.1 - 0.012 15.5 0.1 0.012 15.5 0.1 1.7 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) 7TM_GPCR_Srv PF10323.9 CDJ80172.1 - 0.027 13.8 0.0 0.038 13.3 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv EphA2_TM PF14575.6 CDJ80172.1 - 0.034 15.0 0.1 0.12 13.2 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4064 PF13273.6 CDJ80172.1 - 0.047 14.0 0.0 0.095 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) TMEM210 PF15195.6 CDJ80172.1 - 0.073 13.5 0.2 0.19 12.2 0.2 1.7 1 0 0 1 1 1 0 TMEM210 family Chordopox_A13L PF05961.11 CDJ80172.1 - 0.074 13.3 2.5 0.16 12.2 1.3 2.3 1 1 0 1 1 1 0 Chordopoxvirus A13L protein SLAC1 PF03595.17 CDJ80172.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Voltage-dependent anion channel ECSCR PF15820.5 CDJ80172.1 - 0.12 12.3 2.5 0.28 11.0 2.3 1.8 1 1 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF5305 PF17231.2 CDJ80172.1 - 0.12 11.8 6.2 0.094 12.1 4.3 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5305) HOK_GEF PF01848.16 CDJ80172.1 - 0.14 11.6 5.0 0.22 11.0 5.0 1.3 1 0 0 1 1 1 0 Hok/gef family Shisa PF13908.6 CDJ80172.1 - 0.25 11.5 15.3 0.015 15.5 6.2 2.7 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator DUF4834 PF16118.5 CDJ80172.1 - 1.3 10.0 5.9 1.6 9.7 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) RVT_1 PF00078.27 CDJ80173.1 - 1.6e-08 34.3 0.0 2.3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_12 PF13087.6 CDJ80174.1 - 3.4e-33 114.9 0.0 6.6e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ80174.1 - 1.7e-11 44.4 0.0 4.6e-11 43.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ80174.1 - 1.9e-07 31.0 0.0 0.00097 18.9 0.0 2.7 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 CDJ80174.1 - 8.3e-06 25.7 0.0 0.0032 17.3 0.0 2.7 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 CDJ80174.1 - 0.00029 20.7 0.7 0.67 9.8 0.2 3.3 2 1 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 CDJ80174.1 - 0.071 12.9 0.2 0.34 10.8 0.0 2.3 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain RT_RNaseH PF17917.1 CDJ80175.1 - 1e-27 96.5 0.1 1.9e-27 95.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ80175.1 - 2e-27 95.2 0.0 4.1e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ80175.1 - 9e-17 60.9 0.3 2e-16 59.8 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDJ80175.1 - 1.2e-16 61.0 0.0 3e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CDJ80175.1 - 0.0015 18.7 1.1 0.0048 17.1 0.3 2.2 2 0 0 2 2 2 1 H2C2 zinc finger RVT_3 PF13456.6 CDJ80175.1 - 0.012 15.4 0.1 0.038 13.8 0.0 1.9 2 0 0 2 2 2 0 Reverse transcriptase-like Sybindin PF04099.12 CDJ80176.1 - 5e-32 110.8 0.2 5.6e-32 110.6 0.2 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 CDJ80176.1 - 1.7e-05 25.0 0.1 2.1e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region MIF4G PF02854.19 CDJ80177.1 - 2.3e-35 122.2 7.3 5.3e-35 121.0 7.3 1.7 1 0 0 1 1 1 1 MIF4G domain LtuB PF17455.2 CDJ80177.1 - 0.031 14.9 0.2 0.12 12.9 0.2 2.0 1 0 0 1 1 1 0 Late transcription unit B RINGv PF12906.7 CDJ80178.1 - 2.3e-06 27.6 4.9 2.3e-06 27.6 4.9 1.6 2 0 0 2 2 2 1 RING-variant domain PCIF1_WW PF12237.8 CDJ80179.1 - 0.074 12.7 0.1 0.081 12.5 0.1 1.1 1 0 0 1 1 1 0 Phosphorylated CTD interacting factor 1 WW domain Cpn60_TCP1 PF00118.24 CDJ80180.1 - 5.9e-158 526.5 9.0 6.7e-158 526.3 9.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pro_isomerase PF00160.21 CDJ80181.1 - 3e-41 141.3 0.1 3e-41 141.3 0.1 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 CDJ80181.1 - 2.7e-07 31.2 0.2 0.37 11.8 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ80181.1 - 0.00052 20.3 0.0 3.6 8.0 0.0 3.5 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDJ80181.1 - 0.075 11.7 0.0 7.8 5.0 0.0 2.9 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Recep_L_domain PF01030.24 CDJ80182.1 - 1.5e-11 44.4 0.0 4.1e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Receptor L domain zf-CCCH_7 PF18586.1 CDJ80182.1 - 0.029 14.7 0.0 3.7 8.0 0.0 2.7 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 DUF4543 PF15076.6 CDJ80183.1 - 0.072 13.2 0.1 0.099 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) BTB PF00651.31 CDJ80184.1 - 1.4e-18 67.1 0.2 1.8e-18 66.8 0.2 1.2 1 0 0 1 1 1 1 BTB/POZ domain Pkinase PF00069.25 CDJ80185.1 - 9.1e-15 54.7 0.0 3.1e-13 49.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CDJ80185.1 - 3.1e-08 32.8 0.0 3.7e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 CDJ80185.1 - 4.3e-05 22.9 0.0 8.8e-05 21.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ80185.1 - 0.036 13.4 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RFC1 PF08519.12 CDJ80186.1 - 4e-48 163.5 0.0 2.9e-47 160.7 0.0 2.3 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.29 CDJ80186.1 - 1.4e-15 57.8 0.0 3.7e-15 56.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ80186.1 - 5.1e-05 23.6 0.0 0.00015 22.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CDJ80186.1 - 0.00019 21.4 0.0 0.0012 18.8 0.0 2.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 CDJ80186.1 - 0.00026 20.8 0.0 0.00053 19.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 CDJ80186.1 - 0.0014 18.5 0.6 0.0036 17.1 0.1 2.0 2 0 0 2 2 2 1 DNA polymerase III, delta subunit RuvB_N PF05496.12 CDJ80186.1 - 0.0015 18.3 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDJ80186.1 - 0.0023 18.4 0.0 0.016 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 CDJ80186.1 - 0.0058 16.6 0.2 1.4 8.8 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 CDJ80186.1 - 0.0075 16.3 0.2 0.024 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 CDJ80186.1 - 0.018 15.0 0.7 0.11 12.3 0.1 2.2 1 1 1 2 2 2 0 NTPase RNA_helicase PF00910.22 CDJ80186.1 - 0.053 13.9 0.1 0.38 11.2 0.1 2.3 1 1 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 CDJ80186.1 - 0.069 13.7 0.1 0.38 11.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 CDJ80186.1 - 0.081 12.6 1.4 0.094 12.4 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ABC_membrane_2 PF06472.15 CDJ80187.1 - 3.6e-66 223.3 7.7 4.1e-66 223.2 7.7 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 Mito_carr PF00153.27 CDJ80188.1 - 1.9e-62 207.2 2.4 3.2e-20 71.8 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein His_Phos_1 PF00300.22 CDJ80189.1 - 6.5e-10 39.0 0.0 1.1e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) UDPGT PF00201.18 CDJ80191.1 - 1.2e-62 212.4 0.0 1.6e-62 212.0 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ80191.1 - 6.2e-06 26.3 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain PRTase_3 PF15610.6 CDJ80191.1 - 0.16 11.2 0.3 5.4 6.2 0.0 2.1 2 0 0 2 2 2 0 PRTase ComF-like Striatin PF08232.12 CDJ80192.1 - 1.6e-43 148.9 4.2 1.6e-43 148.9 4.2 2.0 2 0 0 2 2 2 1 Striatin family WD40 PF00400.32 CDJ80192.1 - 1.3e-37 127.1 6.3 3.6e-07 30.8 0.1 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ80192.1 - 9.8e-09 35.4 0.0 0.011 16.0 0.0 5.0 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CDJ80192.1 - 0.001 17.9 0.0 0.038 12.7 0.0 2.5 3 0 0 3 3 3 1 Nup133 N terminal like Prok-E2_A PF14457.6 CDJ80192.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family A UPF0160 PF03690.13 CDJ80193.1 - 7.5e-117 390.5 0.0 8.5e-117 390.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) EST1_DNA_bind PF10373.9 CDJ80195.1 - 2.5e-30 105.9 0.0 3.7e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain PIN_4 PF13638.6 CDJ80195.1 - 9.2e-19 68.0 0.0 2e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 PIN domain EST1 PF10374.9 CDJ80195.1 - 1.7e-14 54.6 1.3 2.1e-14 54.3 0.2 1.9 2 0 0 2 2 2 1 Telomerase activating protein Est1 zf_CCCH_4 PF18345.1 CDJ80196.1 - 0.016 15.3 7.1 1.2e+02 3.0 0.0 6.3 6 0 0 6 6 6 0 Zinc finger domain SNAPc_SNAP43 PF09808.9 CDJ80197.1 - 7.8e-20 71.6 0.9 4.3e-14 52.9 0.3 2.0 1 1 1 2 2 2 2 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 CoA_binding PF02629.19 CDJ80198.1 - 5.8e-31 107.0 1.6 5.8e-31 107.0 1.6 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 CDJ80198.1 - 9.7e-23 80.7 0.3 2.5e-22 79.3 0.3 1.7 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 CDJ80198.1 - 3.3e-08 33.4 0.1 1.9e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CDJ80198.1 - 1.4e-05 25.5 0.0 5e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain IlvN PF07991.12 CDJ80198.1 - 0.0074 15.9 0.1 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain GFO_IDH_MocA PF01408.22 CDJ80198.1 - 0.021 15.7 0.1 0.046 14.6 0.1 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Hint PF01079.20 CDJ80199.1 - 2e-45 154.9 0.1 3.1e-45 154.3 0.1 1.1 1 0 0 1 1 1 1 Hint module Vint PF14623.6 CDJ80199.1 - 0.0015 18.4 0.0 0.0025 17.7 0.0 1.4 1 1 0 1 1 1 1 Hint-domain ADK PF00406.22 CDJ80200.1 - 3.9e-06 27.0 0.0 6.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CDJ80200.1 - 0.0023 18.3 0.0 0.0044 17.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain Coatomer_WDAD PF04053.14 CDJ80201.1 - 2e-81 274.4 1.0 3.1e-79 267.1 0.0 2.2 2 0 0 2 2 2 2 Coatomer WD associated region WD40 PF00400.32 CDJ80201.1 - 3e-44 148.1 7.5 1e-08 35.6 0.1 8.4 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ80201.1 - 1.6e-09 37.9 1.1 0.62 10.4 0.0 6.6 2 2 6 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDJ80201.1 - 0.00017 20.4 6.0 3.3 6.2 0.0 4.3 1 1 3 4 4 4 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 CDJ80201.1 - 0.00041 20.4 1.7 0.75 9.9 0.1 5.0 3 2 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region MetallophosC PF16370.5 CDJ80201.1 - 0.048 13.9 1.6 0.35 11.1 0.7 2.6 1 1 1 2 2 2 0 C terminal of Calcineurin-like phosphoesterase Nucleoporin_N PF08801.11 CDJ80201.1 - 0.24 10.1 2.4 25 3.5 0.1 3.8 2 1 1 4 4 4 0 Nup133 N terminal like Pyr_redox_3 PF13738.6 CDJ80202.1 - 1.9e-14 53.7 0.0 1.3e-12 47.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CDJ80202.1 - 5.8e-07 29.0 0.4 0.00033 20.0 0.2 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CDJ80202.1 - 9e-06 25.0 1.2 8.3e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 CDJ80202.1 - 0.0023 16.5 0.9 0.038 12.4 0.4 2.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.19 CDJ80202.1 - 0.015 14.5 0.3 0.029 13.6 0.3 1.5 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 CDJ80202.1 - 0.056 13.0 0.4 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 CDJ80202.1 - 0.074 13.1 0.0 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Thioredoxin_6 PF13848.6 CDJ80203.1 - 4.6e-21 75.6 0.1 1.7e-20 73.7 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin-like domain TMIE PF16038.5 CDJ80204.1 - 0.12 12.3 3.7 0.17 11.8 3.7 1.2 1 0 0 1 1 1 0 TMIE protein Shisa PF13908.6 CDJ80204.1 - 0.3 11.3 4.5 0.21 11.8 2.3 1.8 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF5056 PF16479.5 CDJ80204.1 - 0.48 10.7 2.1 0.75 10.1 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) ubiquitin PF00240.23 CDJ80205.1 - 2.9e-12 46.1 0.0 6.5e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family zf-AN1 PF01428.16 CDJ80205.1 - 5.3e-05 23.3 12.7 5.3e-05 23.3 12.7 1.8 2 0 0 2 2 2 1 AN1-like Zinc finger Ubiquitin_4 PF18036.1 CDJ80205.1 - 0.023 14.7 0.1 0.089 12.9 0.1 2.1 1 1 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD PF11976.8 CDJ80205.1 - 0.028 14.3 0.0 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 CDJ80205.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain SR-25 PF10500.9 CDJ80205.1 - 8.9 5.9 29.7 0.053 13.1 11.0 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein 7tm_1 PF00001.21 CDJ80206.1 - 1.2e-11 44.5 15.7 1.7e-11 44.0 15.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDJ80206.1 - 2.7e-11 43.3 14.7 3.3e-11 43.1 14.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw ECSCR PF15820.5 CDJ80206.1 - 0.1 12.4 3.3 0.15 11.9 0.1 2.6 3 0 0 3 3 3 0 Endothelial cell-specific chemotaxis regulator Pan3_PK PF18101.1 CDJ80207.1 - 2.6e-62 208.9 0.0 4e-62 208.3 0.0 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain MOR2-PAG1_C PF14225.6 CDJ80207.1 - 0.048 13.5 0.1 0.082 12.8 0.1 1.3 1 0 0 1 1 1 0 Cell morphogenesis C-terminal Calreticulin PF00262.18 CDJ80208.1 - 1.8e-60 204.7 7.9 3.4e-60 203.9 7.9 1.4 1 0 0 1 1 1 1 Calreticulin family TRAM_2 PF18693.1 CDJ80208.1 - 0.073 13.2 0.3 0.21 11.7 0.3 1.8 1 0 0 1 1 1 0 TRAM domain UPF0542 PF15086.6 CDJ80208.1 - 0.082 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 CX PF01705.19 CDJ80209.1 - 4.9e-11 43.0 5.1 9.2e-08 32.5 1.1 2.2 1 1 1 2 2 2 2 CX module 7tm_1 PF00001.21 CDJ80210.1 - 1.2e-11 44.5 15.7 1.7e-11 44.0 15.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDJ80210.1 - 2.7e-11 43.3 14.7 3.3e-11 43.1 14.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw ECSCR PF15820.5 CDJ80210.1 - 0.1 12.4 3.3 0.15 11.9 0.1 2.6 3 0 0 3 3 3 0 Endothelial cell-specific chemotaxis regulator Pan3_PK PF18101.1 CDJ80211.1 - 2.6e-62 208.9 0.0 4e-62 208.3 0.0 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain MOR2-PAG1_C PF14225.6 CDJ80211.1 - 0.048 13.5 0.1 0.082 12.8 0.1 1.3 1 0 0 1 1 1 0 Cell morphogenesis C-terminal Calreticulin PF00262.18 CDJ80212.1 - 1.6e-154 514.2 6.6 2.4e-154 513.7 6.6 1.2 1 0 0 1 1 1 1 Calreticulin family TRAM_2 PF18693.1 CDJ80212.1 - 0.15 12.2 0.3 0.46 10.7 0.3 1.8 1 0 0 1 1 1 0 TRAM domain UPF0542 PF15086.6 CDJ80212.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 CX PF01705.19 CDJ80213.1 - 4.9e-11 43.0 5.1 9.2e-08 32.5 1.1 2.2 1 1 1 2 2 2 2 CX module Thyroglobulin_1 PF00086.18 CDJ80215.1 - 1e-12 47.5 1.2 1e-12 47.5 1.2 1.9 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat SPARC_Ca_bdg PF10591.9 CDJ80215.1 - 9.4e-12 45.3 4.3 2.1e-11 44.2 4.3 1.7 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_7 PF13499.6 CDJ80215.1 - 0.00035 21.0 0.2 0.0035 17.8 0.0 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ80215.1 - 0.00052 19.7 0.0 0.0083 16.0 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CDJ80215.1 - 0.0069 15.9 0.0 0.05 13.2 0.0 2.1 2 0 0 2 2 2 1 EF hand Sulfatase PF00884.23 CDJ80216.1 - 7.1e-75 252.3 0.0 9.2e-75 251.9 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 CDJ80216.1 - 7.4e-24 84.9 0.2 1.4e-23 83.9 0.2 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 CDJ80216.1 - 0.00014 21.6 0.1 0.0011 18.7 0.1 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 CDJ80216.1 - 0.0021 16.8 0.0 0.0026 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF2397 PF09660.10 CDJ80217.1 - 0.0012 17.8 1.7 0.35 9.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2397) DUF3486 PF11985.8 CDJ80217.1 - 0.021 15.3 1.3 1.9 8.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3486) zf-CCHC_4 PF14392.6 CDJ80217.1 - 0.61 9.9 6.7 0.097 12.4 2.4 1.9 2 0 0 2 2 2 0 Zinc knuckle Peptidase_A17 PF05380.13 CDJ80218.1 - 1.6e-37 129.0 0.1 2.4e-37 128.5 0.1 1.3 1 0 0 1 1 1 1 Pao retrotransposon peptidase RVT_1 PF00078.27 CDJ80218.1 - 7.5e-08 32.2 0.0 3.1e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) CD36 PF01130.21 CDJ80219.1 - 1.8e-30 105.9 0.0 2.2e-30 105.6 0.0 1.0 1 0 0 1 1 1 1 CD36 family VEFS-Box PF09733.9 CDJ80220.1 - 0.01 15.7 0.5 0.02 14.7 0.5 1.5 1 0 0 1 1 1 0 VEFS-Box of polycomb protein RAI1 PF08652.11 CDJ80221.1 - 1.1e-15 57.6 0.3 6.5e-15 55.1 0.0 2.1 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease DUF402 PF04167.13 CDJ80222.1 - 0.11 12.7 0.2 0.21 11.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF402) DUF3784 PF12650.7 CDJ80223.1 - 0.047 13.9 4.1 0.036 14.3 2.5 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) VP4_2 PF08935.10 CDJ80224.1 - 0.0045 17.5 0.5 0.0081 16.7 0.5 1.3 1 0 0 1 1 1 1 Viral protein VP4 subunit Integrase_H2C2 PF17921.1 CDJ80225.1 - 1.2e-14 54.1 0.3 3e-14 52.8 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDJ80225.1 - 5.3e-11 42.8 0.0 1.2e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDJ80225.1 - 0.00014 21.6 0.0 0.00072 19.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 CDJ80225.1 - 0.00058 20.0 2.7 0.00058 20.0 2.7 1.8 2 0 0 2 2 2 1 H2C2 zinc finger Integrase_Zn PF02022.19 CDJ80225.1 - 0.056 13.4 0.5 0.45 10.5 0.3 2.5 2 0 0 2 2 2 0 Integrase Zinc binding domain Stanniocalcin PF03298.13 CDJ80226.1 - 5.2e-05 22.7 5.8 6.2e-05 22.4 5.8 1.0 1 0 0 1 1 1 1 Stanniocalcin family DUF167 PF02594.16 CDJ80227.1 - 1.7e-21 76.1 0.3 6.1e-21 74.3 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised ACR, YggU family COG1872 PreAtp-grasp PF18604.1 CDJ80227.1 - 0.046 13.4 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Pre ATP-grasp domain Med28 PF11594.8 CDJ80228.1 - 8.2e-40 136.0 3.9 1.3e-39 135.3 3.1 1.8 2 0 0 2 2 2 1 Mediator complex subunit 28 ApoO PF09769.9 CDJ80228.1 - 0.043 13.8 1.7 1.1 9.2 0.1 2.8 3 0 0 3 3 3 0 Apolipoprotein O QIL1 PF15884.5 CDJ80228.1 - 0.11 13.1 0.0 0.43 11.2 0.0 2.0 1 0 0 1 1 1 0 MICOS complex subunit MIC13, QIL1 zf-H2C2_2 PF13465.6 CDJ80232.1 - 6.1e-14 51.7 41.9 3.8e-05 23.9 0.3 7.0 8 0 0 8 8 8 3 Zinc-finger double domain zf-C2H2 PF00096.26 CDJ80232.1 - 1.8e-13 50.1 45.7 0.0013 19.1 3.8 6.4 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ80232.1 - 4.1e-08 33.4 47.0 0.072 14.0 2.8 6.5 6 0 0 6 6 6 5 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 CDJ80232.1 - 0.043 13.5 0.4 0.043 13.5 0.4 5.1 3 2 3 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain Zn-ribbon_8 PF09723.10 CDJ80232.1 - 0.12 12.5 15.9 0.12 12.5 2.2 4.0 3 1 1 4 4 4 0 Zinc ribbon domain zf-MYST PF17772.1 CDJ80232.1 - 0.21 11.2 2.0 9 6.0 0.5 2.8 2 0 0 2 2 2 0 MYST family zinc finger domain zf-C2H2_jaz PF12171.8 CDJ80232.1 - 0.47 10.8 21.1 0.56 10.6 1.1 4.8 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 CDJ80232.1 - 0.55 11.0 12.9 1 10.2 2.0 3.0 2 1 1 3 3 3 0 zinc-ribbon family zf-C2H2_6 PF13912.6 CDJ80232.1 - 4.7 7.3 30.5 0.46 10.5 1.0 6.4 7 0 0 7 7 7 0 C2H2-type zinc finger zf-RING_7 PF02591.15 CDJ80232.1 - 5.1 7.4 8.0 20 5.5 0.1 4.2 4 0 0 4 4 4 0 C4-type zinc ribbon domain zf-FCS PF06467.14 CDJ80232.1 - 5.2 7.1 14.4 5.2 7.1 5.6 3.3 2 1 1 3 3 3 0 MYM-type Zinc finger with FCS sequence motif Desulfoferrod_N PF06397.12 CDJ80232.1 - 6.4 6.5 12.2 4.9 6.9 0.2 4.0 4 0 0 4 4 4 0 Desulfoferrodoxin, N-terminal domain zf_UBZ PF18439.1 CDJ80232.1 - 8.2 6.1 24.0 1.3 8.7 0.4 5.2 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger Collagen PF01391.18 CDJ80233.1 - 8.7e-27 92.7 82.6 1.8e-10 40.4 28.5 4.0 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) CENP-B_dimeris PF09026.10 CDJ80233.1 - 1.1 9.7 6.9 1.6 9.1 6.9 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Collagen PF01391.18 CDJ80234.1 - 2.7e-26 91.1 76.0 2.6e-09 36.7 27.7 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ80234.1 - 2.4e-10 40.3 0.2 3.2e-10 39.9 0.2 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ80235.1 - 2.5e-23 81.6 72.6 3.4e-10 39.5 25.3 3.8 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ80235.1 - 1.2e-10 41.2 0.9 1.9e-10 40.7 0.9 1.3 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain UCH PF00443.29 CDJ80236.1 - 7.8e-40 137.0 0.0 9.6e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ80236.1 - 2.7e-13 50.2 0.2 6.4e-13 49.0 0.2 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CDJ80236.1 - 1.4e-05 24.8 0.0 3.5e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.6 CDJ80236.1 - 0.0084 15.6 0.0 0.025 14.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Abhydrolase_1 PF00561.20 CDJ80237.1 - 6e-11 42.5 0.0 1.7e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF818 PF05677.12 CDJ80237.1 - 1.2e-05 24.5 0.0 5.8e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_6 PF12697.7 CDJ80237.1 - 2.8e-05 24.8 0.0 0.00015 22.4 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDJ80237.1 - 2.9e-05 23.4 0.1 0.026 13.8 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 CDJ80237.1 - 0.00013 21.9 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 CDJ80237.1 - 0.00054 19.7 0.0 0.0012 18.5 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 CDJ80237.1 - 0.014 14.9 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 CDJ80237.1 - 0.04 13.4 0.1 0.27 10.7 0.1 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF1758 PF05585.12 CDJ80238.1 - 4.7e-05 23.2 0.3 0.00014 21.7 0.3 1.8 1 0 0 1 1 1 1 Putative peptidase (DUF1758) DUF3109 PF11307.8 CDJ80238.1 - 0.0085 15.9 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3109) FXMRP1_C_core PF12235.8 CDJ80240.1 - 2 9.1 6.6 0.85 10.3 2.8 2.3 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal TFIIA PF03153.13 CDJ80240.1 - 2.9 7.8 11.7 4.9 7.0 11.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NARG2_C PF10505.9 CDJ80241.1 - 6.4e-06 25.8 0.0 1.8e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus Ribosomal_L7Ae PF01248.26 CDJ80242.1 - 6.4e-29 99.5 0.3 4e-20 71.4 0.1 2.3 1 1 1 2 2 2 2 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RTP1_C1 PF10363.9 CDJ80242.1 - 0.048 13.8 0.8 22 5.3 0.0 3.2 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 AMPK1_CBM PF16561.5 CDJ80242.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase baeRF_family2 PF18844.1 CDJ80242.1 - 0.6 10.2 5.4 11 6.0 0.2 3.0 2 1 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 2 Malate_DH PF12434.8 CDJ80242.1 - 8.8 6.4 6.6 2.3 8.3 1.7 2.5 2 0 0 2 2 2 0 Malate dehydrogenase enzyme Metallophos PF00149.28 CDJ80243.1 - 5.2e-11 43.4 0.0 1e-10 42.5 0.0 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos PF00149.28 CDJ80244.1 - 5.9e-39 134.7 0.0 8.9e-39 134.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDJ80244.1 - 2.3e-08 34.3 0.1 4.3e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DUF1759 PF03564.15 CDJ80245.1 - 3.3e-20 72.5 2.5 3.3e-20 72.5 2.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 CDJ80245.1 - 3.9e-09 36.5 0.0 3.9e-09 36.5 0.0 2.7 3 0 0 3 3 3 1 Putative peptidase (DUF1758) zf-CCHC PF00098.23 CDJ80245.1 - 2.6e-05 24.1 19.8 0.00079 19.4 0.9 3.5 3 0 0 3 3 3 2 Zinc knuckle Asp_protease_2 PF13650.6 CDJ80245.1 - 0.00013 22.5 0.0 0.00049 20.7 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ80245.1 - 0.0004 20.9 0.0 0.0016 18.9 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zinc_ribbon_2 PF13240.6 CDJ80245.1 - 0.12 12.1 0.9 21 5.0 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon domain CorA PF01544.18 CDJ80245.1 - 1.7 7.9 8.1 0.28 10.4 1.7 2.6 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein ThylakoidFormat PF11264.8 CDJ80245.1 - 4.6 6.9 6.6 2.4 7.8 0.1 2.8 3 0 0 3 3 3 0 Thylakoid formation protein zf-C4pol PF14260.6 CDJ80245.1 - 7.6 7.1 15.2 3.9 8.0 11.9 2.4 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta PHD_4 PF16866.5 CDJ80246.1 - 0.025 14.7 1.2 0.025 14.7 1.2 2.0 2 1 0 2 2 2 0 PHD-finger DUF753 PF05444.12 CDJ80246.1 - 0.46 10.5 8.8 3 7.8 4.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF753) QVR PF17064.5 CDJ80246.1 - 3 8.2 7.9 6.8 7.0 7.9 1.7 1 1 0 1 1 1 0 Sleepless protein RT_RNaseH PF17917.1 CDJ80247.1 - 0.0026 18.0 0.9 0.022 15.1 0.3 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ80247.1 - 0.043 13.9 0.9 0.079 13.0 0.2 1.7 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Peptidase_C36 PF05415.11 CDJ80247.1 - 0.096 12.9 0.1 0.14 12.4 0.1 1.2 1 0 0 1 1 1 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase LPD11 PF18824.1 CDJ80247.1 - 2.3 8.3 5.9 14 5.8 1.7 2.3 2 1 0 2 2 2 0 Large polyvalent protein-associated domain 11 RVT_1 PF00078.27 CDJ80248.1 - 0.011 15.2 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) LicD PF04991.13 CDJ80249.1 - 0.0016 18.6 0.1 0.007 16.5 0.0 2.0 2 1 0 2 2 2 1 LicD family DUF1679 PF07914.11 CDJ80250.1 - 4.8e-46 157.5 0.0 5.3e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 CDJ80250.1 - 4e-15 55.9 0.0 1.3e-14 54.2 0.0 1.7 2 0 0 2 2 2 1 Ecdysteroid kinase APH PF01636.23 CDJ80250.1 - 3.2e-05 24.0 0.0 3.8e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Patched PF02460.18 CDJ80251.1 - 3.2e-271 902.1 7.9 3.7e-271 901.8 7.9 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 CDJ80251.1 - 1.5e-33 115.8 4.7 1.5e-33 115.8 4.7 2.7 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation DUF1736 PF08409.11 CDJ80251.1 - 6.9 6.7 7.1 26 4.9 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1736) MIG-14_Wnt-bd PF06664.12 CDJ80253.1 - 3e-77 259.7 15.8 3e-77 259.7 15.8 1.4 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion PglZ PF08665.12 CDJ80254.1 - 0.066 13.3 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 PglZ domain DUF5638 PF18688.1 CDJ80254.1 - 0.096 13.0 0.0 35 4.8 0.0 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5638) MutS_II PF05188.17 CDJ80254.1 - 0.23 11.8 0.9 4.4 7.6 0.0 2.3 2 0 0 2 2 2 0 MutS domain II Coatomer_WDAD PF04053.14 CDJ80256.1 - 3.3e-08 33.0 7.8 0.046 12.8 0.2 3.7 3 1 1 4 4 4 3 Coatomer WD associated region TPR_7 PF13176.6 CDJ80256.1 - 4.6e-08 32.6 17.6 0.00094 19.0 0.3 8.2 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ80256.1 - 0.0065 16.5 1.5 0.0065 16.5 1.5 9.0 9 2 1 10 10 10 1 Tetratricopeptide repeat Clathrin PF00637.20 CDJ80256.1 - 0.011 15.6 20.0 1.7 8.5 0.1 6.6 6 2 2 8 8 8 0 Region in Clathrin and VPS TPR_1 PF00515.28 CDJ80256.1 - 0.013 15.3 0.8 0.013 15.3 0.8 6.3 8 1 1 9 9 9 0 Tetratricopeptide repeat RPN7 PF10602.9 CDJ80256.1 - 0.013 15.2 14.0 0.096 12.4 0.1 5.8 3 2 3 6 6 6 0 26S proteasome subunit RPN7 TPR_14 PF13428.6 CDJ80256.1 - 0.015 16.0 20.1 24 6.1 0.2 8.5 5 1 4 9 9 9 0 Tetratricopeptide repeat NOP5NT PF08156.13 CDJ80256.1 - 0.11 12.9 1.2 0.38 11.2 0.3 2.5 2 0 0 2 2 2 0 NOP5NT (NUC127) domain TPR_12 PF13424.6 CDJ80256.1 - 0.17 12.2 22.1 0.88 9.9 0.7 7.1 5 1 2 7 7 7 0 Tetratricopeptide repeat HHH_8 PF14716.6 CDJ80256.1 - 2.5 8.5 10.0 4.9 7.6 0.1 4.6 4 1 1 5 5 5 0 Helix-hairpin-helix domain Pkinase PF00069.25 CDJ80257.1 - 1.8e-64 217.6 0.0 3e-62 210.4 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ80257.1 - 3.4e-29 101.9 0.0 1.1e-21 77.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDJ80257.1 - 0.00016 21.1 0.1 0.0012 18.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CDJ80257.1 - 0.0009 19.2 0.1 0.038 13.9 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDJ80257.1 - 0.002 17.2 0.2 0.004 16.2 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CDJ80257.1 - 0.0029 17.0 0.0 0.0064 15.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDJ80257.1 - 0.036 12.8 0.0 0.12 11.1 0.0 1.8 1 1 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 CDJ80257.1 - 0.11 11.4 0.1 0.19 10.6 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.11 CDJ80257.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RNA_pol_Rpb1_1 PF04997.12 CDJ80258.1 - 7.7e-88 294.8 0.1 9.1e-88 294.6 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 CDJ80258.1 - 1.3e-23 84.0 0.0 2.8e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RVT_1 PF00078.27 CDJ80259.1 - 8.1e-05 22.2 0.0 0.00013 21.6 0.0 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ccdc124 PF06244.12 CDJ80259.1 - 0.1 13.1 0.1 0.19 12.3 0.1 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 124 /Oxs1 RNA_pol_Rpb1_3 PF04983.18 CDJ80260.1 - 7.1e-27 94.3 0.0 8.2e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_2 PF00623.20 CDJ80260.1 - 0.0031 17.8 0.1 0.0049 17.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 HTH_17 PF12728.7 CDJ80262.1 - 0.0073 16.5 0.8 0.35 11.1 0.1 3.0 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_33 PF13592.6 CDJ80262.1 - 0.018 14.7 0.1 0.052 13.2 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn helix Phage_AlpA PF05930.12 CDJ80262.1 - 0.11 12.3 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) HTH_7 PF02796.15 CDJ80262.1 - 0.15 12.2 0.1 24 5.1 0.0 3.1 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 CDJ80262.1 - 0.17 11.7 0.5 1.3 8.9 0.0 2.5 3 0 0 3 3 3 0 Homeodomain-like domain HTH_IclR PF09339.10 CDJ80262.1 - 0.26 11.1 1.6 8 6.4 0.0 2.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain DNA_pol_phi PF04931.13 CDJ80262.1 - 0.69 7.9 4.6 1 7.4 4.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi RVT_1 PF00078.27 CDJ80265.1 - 4.2e-18 65.7 0.0 1.8e-08 34.2 0.0 2.0 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 CDJ80266.1 - 1.2e-23 82.9 15.5 5.3e-07 30.2 0.7 7.1 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ80266.1 - 1.1e-14 54.4 1.2 0.00037 20.7 0.0 6.1 2 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CDJ80266.1 - 0.0016 17.9 3.7 0.32 10.3 0.5 2.8 1 1 2 3 3 3 3 WD40-like domain Mcl1_mid PF12341.8 CDJ80266.1 - 0.0059 16.0 2.1 0.13 11.6 0.0 2.2 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region DUF4062 PF13271.6 CDJ80266.1 - 0.019 15.4 0.0 0.087 13.2 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) Atg8 PF02991.16 CDJ80266.1 - 0.065 13.4 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like AARP2CN PF08142.12 CDJ80267.1 - 0.069 13.2 0.1 0.19 11.8 0.1 1.8 1 0 0 1 1 1 0 AARP2CN (NUC121) domain RVT_1 PF00078.27 CDJ80268.1 - 5.3e-05 22.8 0.0 9.3e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HlyIII PF03006.20 CDJ80269.1 - 2.4e-70 236.8 21.6 3e-70 236.5 21.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related IPP-2 PF04979.14 CDJ80270.1 - 1.9e-34 119.2 1.5 2.5e-34 118.9 1.5 1.1 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) Nucleoside_tran PF01733.18 CDJ80271.1 - 2.4e-66 224.2 25.8 1.9e-64 218.0 23.4 2.6 1 1 1 2 2 2 1 Nucleoside transporter DUF624 PF04854.14 CDJ80271.1 - 0.24 11.5 0.1 0.24 11.5 0.1 3.7 3 2 0 3 3 3 0 Protein of unknown function, DUF624 RNA_pol_Rpc34 PF05158.12 CDJ80272.1 - 3.5e-51 174.6 6.7 1.4e-49 169.3 6.7 2.4 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 CDJ80272.1 - 0.0024 18.0 0.8 0.0042 17.2 0.1 1.8 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC GntR PF00392.21 CDJ80272.1 - 0.051 13.2 0.1 0.26 10.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family TrmB PF01978.19 CDJ80272.1 - 0.089 12.7 0.2 0.38 10.7 0.1 2.1 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB RPA_C PF08784.11 CDJ80272.1 - 0.14 12.8 0.2 2.9 8.6 0.0 2.3 1 1 1 2 2 2 0 Replication protein A C terminal Tcf25 PF04910.14 CDJ80273.1 - 2.2e-71 240.8 1.8 3.3e-71 240.2 1.8 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 CTP_transf_like PF01467.26 CDJ80273.1 - 0.23 11.7 2.0 0.29 11.3 0.2 2.2 2 0 0 2 2 2 0 Cytidylyltransferase-like SR-25 PF10500.9 CDJ80273.1 - 1.9 8.0 14.6 0.044 13.4 7.3 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 CDJ80274.1 - 6.3e-63 212.6 0.0 7.9e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ80274.1 - 4e-31 108.3 0.0 6.4e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase GCV_T PF01571.21 CDJ80274.1 - 1e-08 34.9 0.0 1.5e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Kdo PF06293.14 CDJ80274.1 - 4e-06 26.3 0.0 5.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDJ80274.1 - 0.00076 18.5 0.1 0.002 17.1 0.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CDJ80274.1 - 0.0028 17.0 0.0 0.0083 15.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CDJ80274.1 - 0.0036 17.3 0.1 0.072 13.0 0.1 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 CDJ80274.1 - 0.16 11.5 0.1 4.7 6.8 0.1 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 CDJ80274.1 - 0.19 11.3 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF2650 PF10853.8 CDJ80275.1 - 3.5e-18 65.0 3.8 3.5e-18 65.0 3.8 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2650) EssA PF10661.9 CDJ80276.1 - 0.03 14.2 0.2 0.14 12.0 0.2 2.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF4200 PF13863.6 CDJ80276.1 - 3.6 8.0 9.7 2.4 8.6 3.7 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) SapB_2 PF03489.17 CDJ80277.1 - 2.2e-05 24.5 2.4 2.2e-05 24.5 2.4 2.0 2 0 0 2 2 2 1 Saposin-like type B, region 2 SapB_1 PF05184.15 CDJ80277.1 - 0.00073 19.5 4.5 0.0014 18.6 0.7 2.7 2 1 0 2 2 2 1 Saposin-like type B, region 1 HMGL-like PF00682.19 CDJ80277.1 - 0.091 12.3 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 HMGL-like zf-FCS PF06467.14 CDJ80277.1 - 0.11 12.5 1.2 0.73 9.8 0.3 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif PTPS PF01242.19 CDJ80279.1 - 1.4e-30 105.8 0.2 1.6e-30 105.6 0.2 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase CH PF00307.31 CDJ80280.1 - 8.8e-11 42.0 0.5 1.1e-10 41.6 0.2 1.3 2 0 0 2 2 2 1 Calponin homology (CH) domain Calponin PF00402.18 CDJ80280.1 - 1.7e-10 40.3 2.7 2.9e-10 39.6 2.7 1.4 1 0 0 1 1 1 1 Calponin family repeat Dec-1 PF04624.14 CDJ80280.1 - 0.096 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Dec-1 repeat PAN_1 PF00024.26 CDJ80282.1 - 0.00014 21.7 0.2 0.00014 21.7 0.2 2.7 2 0 0 2 2 2 1 PAN domain Collagen PF01391.18 CDJ80283.1 - 1.1e-22 79.6 111.5 2.9e-09 36.5 30.3 4.1 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ80283.1 - 2.1e-19 69.3 1.3 2.7e-19 68.9 1.3 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain COX14 PF14880.6 CDJ80283.1 - 0.31 10.9 0.8 0.47 10.3 0.8 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Chromo PF00385.24 CDJ80284.1 - 8.3e-17 60.8 0.7 1.8e-13 50.1 0.7 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 CDJ80284.1 - 0.00022 21.3 0.0 0.93 9.6 0.1 2.6 2 0 0 2 2 2 2 Chromo shadow domain Col_cuticle_N PF01484.17 CDJ80285.1 - 1.9e-18 66.3 0.6 2.5e-18 65.9 0.6 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ80285.1 - 2.8e-18 65.4 84.5 5.6e-10 38.8 36.9 3.3 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) 7tm_1 PF00001.21 CDJ80286.1 - 9.9e-47 159.5 8.3 9.9e-47 159.5 8.3 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ80286.1 - 8e-09 35.3 6.7 3.1e-08 33.3 6.7 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 CDJ80286.1 - 1e-05 25.3 6.1 1e-05 25.3 6.1 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4834 PF16118.5 CDJ80286.1 - 6.4 7.8 5.7 44 5.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) 7tm_2 PF00002.24 CDJ80287.1 - 1.4e-29 103.1 13.5 1.4e-27 96.6 13.5 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 CDJ80287.1 - 9.7e-08 32.2 6.6 9.7e-08 32.2 6.6 1.9 2 0 0 2 2 2 1 Hormone receptor domain Ubiq_cyt_C_chap PF03981.12 CDJ80288.1 - 5.4e-27 94.6 1.0 8.7e-27 93.9 1.0 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Soc PF16855.5 CDJ80288.1 - 0.074 13.6 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Small outer capsid protein zf-AN1 PF01428.16 CDJ80289.1 - 1.5e-15 57.1 36.7 1.2e-08 34.9 14.6 2.3 2 0 0 2 2 2 2 AN1-like Zinc finger Corona_NS8 PF12093.8 CDJ80289.1 - 0.0088 16.6 0.4 0.047 14.3 0.3 2.0 2 0 0 2 2 2 1 Coronavirus NS8 protein Transp_Tc5_C PF04236.15 CDJ80289.1 - 3.4 8.1 23.8 8.1 6.9 8.1 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain PDZ PF00595.24 CDJ80290.1 - 9.3e-26 90.0 0.1 5.8e-09 36.2 0.0 3.7 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 CDJ80290.1 - 2e-15 56.4 0.3 4.2e-07 29.7 0.0 3.7 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 CDJ80290.1 - 3.2e-10 40.2 0.9 0.00045 20.5 0.1 3.6 3 0 0 3 3 3 3 PDZ domain Par3_HAL_N_term PF12053.8 CDJ80290.1 - 0.00026 21.2 1.9 0.00057 20.0 1.9 1.6 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins U1snRNP70_N PF12220.8 CDJ80290.1 - 0.018 15.7 2.1 0.16 12.7 2.1 2.7 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Synaphin PF05835.12 CDJ80290.1 - 0.85 9.9 8.6 1.3 9.3 6.9 2.0 2 0 0 2 2 2 0 Synaphin protein TUDOR PF00567.24 CDJ80291.1 - 6.1e-10 39.2 0.0 1.4e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Tudor domain OST-HTH PF12872.7 CDJ80291.1 - 1.8e-09 37.3 0.0 5.1e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 OST-HTH/LOTUS domain TFCD_C PF12612.8 CDJ80292.1 - 3.7e-27 95.4 0.7 1.3e-26 93.6 0.7 2.0 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 CDJ80292.1 - 1.2e-06 28.8 5.9 8.5 6.8 0.0 7.4 8 0 0 8 8 8 2 HEAT repeats HEAT PF02985.22 CDJ80292.1 - 1.6e-05 24.7 25.1 0.57 10.6 0.1 9.0 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.6 CDJ80292.1 - 7.4e-05 23.2 12.9 0.27 11.8 0.0 8.2 9 1 0 9 9 9 2 HEAT-like repeat LBP_BPI_CETP_C PF02886.17 CDJ80294.1 - 1.5e-18 67.1 0.0 9.2e-12 44.9 0.0 2.2 2 0 0 2 2 2 2 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 CDJ80294.1 - 4.5e-13 49.1 0.6 1.5e-12 47.4 0.1 2.0 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain COesterase PF00135.28 CDJ80295.1 - 6.5e-131 437.7 0.0 8.2e-131 437.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDJ80295.1 - 5.4e-10 39.5 0.1 1.8e-09 37.8 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF5520 PF17658.1 CDJ80295.1 - 0.13 11.4 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5520) DEK_C PF08766.11 CDJ80296.1 - 1.1e-09 38.1 0.1 3.7e-09 36.4 0.1 2.0 1 0 0 1 1 1 1 DEK C terminal domain BAP PF06639.11 CDJ80296.1 - 0.12 12.7 0.2 26 5.3 0.1 2.7 2 0 0 2 2 2 0 Basal layer antifungal peptide (BAP) Mitofilin PF09731.9 CDJ80296.1 - 1.7 7.4 45.5 2.4 6.9 22.0 2.1 2 0 0 2 2 2 0 Mitochondrial inner membrane protein CNDH2_C PF16858.5 CDJ80296.1 - 3.9 7.3 29.8 0.18 11.7 11.3 2.4 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term BUD22 PF09073.10 CDJ80296.1 - 8.9 5.5 61.1 0.23 10.8 26.7 2.2 2 0 0 2 2 2 0 BUD22 Ras PF00071.22 CDJ80297.1 - 9.5e-67 223.6 0.5 1.2e-66 223.3 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ80297.1 - 2.5e-35 121.3 0.2 5.3e-35 120.2 0.2 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ80297.1 - 3.3e-16 59.2 0.2 4.3e-16 58.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ80297.1 - 8.7e-06 25.2 0.1 1.1e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CDJ80297.1 - 0.0002 20.8 0.1 0.00029 20.3 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CDJ80297.1 - 0.0004 20.0 0.1 0.00063 19.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDJ80297.1 - 0.0028 17.7 0.0 0.0052 16.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ80297.1 - 0.0054 16.7 0.3 3.1 7.7 0.1 2.4 2 1 0 2 2 2 2 RsgA GTPase DUF3963 PF13124.6 CDJ80297.1 - 0.022 14.7 0.8 0.045 13.7 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) PduV-EutP PF10662.9 CDJ80297.1 - 0.029 14.1 0.0 0.063 13.0 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 CDJ80297.1 - 0.081 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TraT PF05818.12 CDJ80297.1 - 0.11 12.1 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein MADF_DNA_bdg PF10545.9 CDJ80298.1 - 7.3e-14 51.9 3.3 1.5e-13 50.9 3.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 CDJ80298.1 - 1.4e-07 31.8 2.7 2.4e-07 31.0 2.7 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 CDJ80298.1 - 2e-05 24.6 2.5 4.5e-05 23.4 2.5 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain PCMT PF01135.19 CDJ80299.1 - 1.4e-25 90.3 0.0 2.2e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SOCS_box PF07525.16 CDJ80299.1 - 1.5e-05 25.3 0.3 0.021 15.2 0.1 2.4 2 0 0 2 2 2 2 SOCS box DOT1 PF08123.13 CDJ80299.1 - 5.2e-05 22.9 0.0 8.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 GCD14 PF08704.10 CDJ80299.1 - 0.038 13.7 2.2 0.043 13.5 0.0 2.1 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Ubie_methyltran PF01209.18 CDJ80299.1 - 0.063 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 CDJ80299.1 - 0.091 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase LAP1C PF05609.12 CDJ80299.1 - 7.7 5.5 17.9 12 4.9 17.9 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TAF4 PF05236.14 CDJ80300.1 - 1.1e-23 84.4 2.7 1.1e-23 84.4 2.7 2.9 1 1 2 3 3 3 2 Transcription initiation factor TFIID component TAF4 family TAFH PF07531.14 CDJ80300.1 - 1.3e-11 44.4 0.0 1.3e-11 44.4 0.0 2.8 3 1 0 3 3 3 1 NHR1 homology to TAF Med19 PF10278.9 CDJ80300.1 - 0.048 13.6 0.3 0.048 13.6 0.3 2.2 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 adh_short PF00106.25 CDJ80302.1 - 3e-17 62.7 0.0 3.4e-17 62.5 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ80302.1 - 1.8e-13 50.6 0.0 2.1e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CDJ80302.1 - 0.00025 20.6 0.1 0.00029 20.4 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 CDJ80302.1 - 0.0074 15.7 0.0 0.0081 15.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 CDJ80302.1 - 0.16 11.0 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short_C2 PF13561.6 CDJ80303.1 - 3.5e-11 43.1 0.0 3.8e-11 43.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Peptidase_M24 PF00557.24 CDJ80304.1 - 3.1e-41 141.4 0.0 4.3e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CDJ80304.1 - 2.1e-18 66.2 0.0 3.8e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Kelch_1 PF01344.25 CDJ80305.1 - 1.3e-47 159.1 1.5 1.3e-12 47.1 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CDJ80305.1 - 1e-28 98.6 0.3 1.1e-05 25.5 0.0 6.3 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.15 CDJ80305.1 - 5.5e-18 64.2 0.2 0.0011 18.8 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 CDJ80305.1 - 4.4e-16 58.6 0.9 0.00083 19.3 0.0 6.3 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ80305.1 - 4.8e-15 55.4 0.9 0.0023 18.1 0.0 5.3 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ80305.1 - 2.1e-09 37.2 1.4 0.11 12.6 0.0 5.7 6 0 0 6 6 6 3 Kelch motif BTB PF00651.31 CDJ80305.1 - 3.6e-07 30.4 0.2 6.8e-07 29.5 0.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 CDJ80305.1 - 0.12 12.5 0.5 0.29 11.3 0.1 1.7 2 0 0 2 2 2 0 BTB And C-terminal Kelch DUF3342 PF11822.8 CDJ80305.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) adh_short PF00106.25 CDJ80306.1 - 1.6e-26 93.0 0.3 2.9e-26 92.1 0.3 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ80306.1 - 3.5e-20 72.6 0.1 8.1e-20 71.4 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 CDJ80306.1 - 1.1e-06 28.6 0.1 3e-06 27.3 0.1 1.6 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 CDJ80306.1 - 4.3e-06 26.7 0.0 8.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDJ80306.1 - 0.0059 16.1 0.0 0.009 15.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CDJ80306.1 - 0.016 14.4 0.3 0.026 13.7 0.3 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 CDJ80306.1 - 0.074 12.0 0.1 0.13 11.2 0.1 1.3 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Patched PF02460.18 CDJ80307.1 - 3.9e-62 210.5 0.3 5e-62 210.1 0.3 1.2 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 CDJ80307.1 - 0.0013 18.6 3.6 0.0013 18.6 3.6 2.1 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation Collagen PF01391.18 CDJ80308.1 - 4.2e-25 87.3 86.6 9.6e-10 38.1 27.3 4.1 2 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) tRNA-synt_1e PF01406.19 CDJ80309.1 - 5.8e-124 413.3 2.1 2.1e-123 411.5 2.1 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 CDJ80309.1 - 6e-08 31.8 1.4 0.00048 19.0 0.1 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1c PF00749.21 CDJ80309.1 - 0.0002 20.4 0.0 0.0002 20.4 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1 PF00133.22 CDJ80309.1 - 0.006 14.9 0.1 0.12 10.6 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 CDJ80309.1 - 0.011 14.6 6.4 0.02 13.8 0.0 3.2 3 1 0 3 3 3 0 tRNA synthetases class I (K) NDUFB10 PF10249.9 CDJ80309.1 - 0.029 14.9 0.4 0.12 12.9 0.4 2.0 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 Dna2 PF08696.11 CDJ80309.1 - 0.12 12.1 0.8 5.8 6.7 0.0 2.4 1 1 0 2 2 2 0 DNA replication factor Dna2 Astacin PF01400.24 CDJ80311.1 - 7e-33 113.8 0.0 8.1e-33 113.6 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) DUF3152 PF11350.8 CDJ80311.1 - 0.2 11.3 0.7 0.29 10.8 0.4 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3152) Pkinase PF00069.25 CDJ80312.1 - 2.2e-71 240.3 0.0 3.3e-71 239.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain POLO_box PF00659.18 CDJ80312.1 - 4.5e-41 138.9 0.5 4.1e-21 74.9 0.1 2.6 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_Tyr PF07714.17 CDJ80312.1 - 7.9e-41 140.0 0.0 1.4e-40 139.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ80312.1 - 1.2e-09 37.9 0.0 2.9e-08 33.4 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CDJ80312.1 - 3.5e-05 22.8 0.0 6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDJ80312.1 - 0.081 12.3 0.1 0.24 10.7 0.1 1.8 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Leo1 PF04004.13 CDJ80313.1 - 4.1e-49 166.6 0.3 9.6e-49 165.4 0.3 1.7 1 0 0 1 1 1 1 Leo1-like protein AFT PF08731.11 CDJ80313.1 - 0.13 12.7 0.1 0.13 12.7 0.1 3.1 4 0 0 4 4 4 0 Transcription factor AFT GRAM PF02893.20 CDJ80314.1 - 5.5e-06 26.3 0.0 1.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 GRAM domain PRT_C PF08372.10 CDJ80314.1 - 6.9e-05 22.6 0.8 6.9e-05 22.6 0.8 1.8 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal Pex24p PF06398.11 CDJ80314.1 - 0.00092 18.3 4.8 0.23 10.4 1.7 2.3 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin DUF639 PF04842.12 CDJ80314.1 - 0.19 11.1 2.1 0.17 11.3 0.2 1.8 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) Reticulon PF02453.17 CDJ80314.1 - 1.2 9.0 12.0 4.2 7.3 11.4 2.0 1 1 1 2 2 2 0 Reticulon Moulting_cycle PF04870.16 CDJ80315.1 - 4.4e-06 26.2 5.8 4.4e-06 26.2 5.8 2.0 2 0 0 2 2 2 1 Moulting cycle CNOT11 PF10155.9 CDJ80315.1 - 0.0052 17.0 1.1 0.019 15.1 0.1 2.0 1 1 1 2 2 2 1 CCR4-NOT transcription complex subunit 11 HTH_30 PF13556.6 CDJ80315.1 - 0.018 14.8 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain MADF_DNA_bdg PF10545.9 CDJ80315.1 - 0.029 14.7 2.4 0.029 14.7 2.4 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like FUSC PF04632.12 CDJ80315.1 - 0.11 11.0 0.6 0.14 10.7 0.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family HTH_48 PF17906.1 CDJ80316.1 - 6.1e-05 23.1 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_26 PF13443.6 CDJ80317.1 - 0.0021 18.4 0.1 0.0042 17.5 0.1 1.5 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_IclR PF09339.10 CDJ80317.1 - 0.0065 16.2 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 CDJ80317.1 - 0.0095 15.8 0.1 0.021 14.7 0.1 1.6 1 0 0 1 1 1 1 MarR family DUF3602 PF12223.8 CDJ80317.1 - 0.028 15.0 0.2 0.065 13.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) DUF4572 PF15139.6 CDJ80317.1 - 0.03 14.3 0.1 0.06 13.3 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4572) HTH_32 PF13565.6 CDJ80317.1 - 0.16 12.6 2.0 0.64 10.7 0.2 2.4 2 0 0 2 2 2 0 Homeodomain-like domain Miga PF10265.9 CDJ80319.1 - 1.1e-37 130.3 0.0 1.2e-37 130.2 0.0 1.0 1 0 0 1 1 1 1 Mitoguardin Flp1_like PF16982.5 CDJ80319.1 - 0.068 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain Miga PF10265.9 CDJ80320.1 - 2.6e-60 204.9 0.0 3.7e-58 197.8 0.1 2.0 1 1 1 2 2 2 2 Mitoguardin Motile_Sperm PF00635.26 CDJ80321.1 - 1.1e-07 31.7 0.0 1.8e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Ras PF00071.22 CDJ80322.1 - 1.3e-27 96.4 0.0 1.6e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ80322.1 - 1.7e-05 25.0 0.0 3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDJ80323.1 - 2.6e-21 75.9 0.1 3.1e-21 75.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ80323.1 - 8.5e-12 45.3 0.0 9.2e-12 45.2 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ80323.1 - 3.6e-07 29.8 0.0 3.8e-07 29.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 CDJ80323.1 - 0.088 12.3 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 CDJ80323.1 - 0.17 11.3 0.0 0.18 11.2 0.0 1.0 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Sid-5 PF17204.3 CDJ80325.1 - 1.8 8.8 10.2 3.3 7.9 0.3 2.9 3 0 0 3 3 3 0 Sid-5 family DUF1158 PF06643.11 CDJ80325.1 - 2.9 8.5 8.5 0.87 10.1 0.1 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1158) 7tm_1 PF00001.21 CDJ80325.1 - 6.2 6.1 20.5 0.089 12.1 13.4 1.5 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) SCVP PF17619.2 CDJ80326.1 - 1.8e-06 28.7 0.1 2.5e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 Secreted clade V proteins SCVP PF17619.2 CDJ80327.1 - 1.2e-08 35.7 1.5 1.5e-08 35.4 1.5 1.1 1 0 0 1 1 1 1 Secreted clade V proteins SCVP PF17619.2 CDJ80328.1 - 8.6e-14 52.2 0.0 1.1e-13 51.9 0.0 1.1 1 0 0 1 1 1 1 Secreted clade V proteins TIMELESS PF04821.14 CDJ80329.1 - 1.1e-52 179.1 1.1 2.5e-52 177.9 1.1 1.7 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 CDJ80329.1 - 2.1e-26 93.2 3.0 2.1e-26 93.2 3.0 4.0 3 1 1 4 4 4 2 Timeless protein C terminal region DUF4844 PF16133.5 CDJ80329.1 - 0.052 14.1 0.2 0.45 11.1 0.2 2.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) WD40 PF00400.32 CDJ80330.1 - 0.0015 19.3 3.5 37 5.4 0.0 5.3 6 0 0 6 6 6 0 WD domain, G-beta repeat PQQ_3 PF13570.6 CDJ80330.1 - 0.0025 18.3 0.0 1.3 9.6 0.0 3.3 3 0 0 3 3 3 1 PQQ-like domain Mpp10 PF04006.12 CDJ80330.1 - 0.0078 14.7 17.0 0.011 14.2 17.0 1.3 1 0 0 1 1 1 1 Mpp10 protein SAPS PF04499.15 CDJ80330.1 - 0.026 13.3 1.4 0.026 13.3 1.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BBS2_Mid PF14783.6 CDJ80330.1 - 0.056 13.5 0.0 0.84 9.7 0.0 2.7 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region RNA_pol_3_Rpc31 PF11705.8 CDJ80330.1 - 2.3 8.4 33.3 3.5 7.8 33.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 CDJ80330.1 - 3.9 6.7 21.3 5.3 6.3 21.3 1.2 1 0 0 1 1 1 0 BUD22 DUF913 PF06025.12 CDJ80330.1 - 4.3 6.2 4.8 5.9 5.8 4.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 CDJ80330.1 - 8.3 5.1 7.0 11 4.6 7.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PPP4R2 PF09184.11 CDJ80330.1 - 9.6 5.7 23.0 13 5.2 23.0 1.2 1 0 0 1 1 1 0 PPP4R2 zf-HIT PF04438.16 CDJ80331.1 - 2.6e-08 33.6 12.6 5.1e-08 32.7 12.6 1.5 1 0 0 1 1 1 1 HIT zinc finger HTH_AsnC-type PF13404.6 CDJ80331.1 - 0.083 12.7 1.8 3.1 7.7 0.1 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain zf-HC2 PF13490.6 CDJ80331.1 - 0.22 11.8 0.0 0.22 11.8 0.0 3.6 4 0 0 4 4 4 0 Putative zinc-finger PolC_DP2 PF03833.13 CDJ80331.1 - 1.2 6.9 6.3 1.4 6.7 6.3 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Ribosomal_L21p PF00829.21 CDJ80332.1 - 7.1e-17 61.5 0.0 1.1e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein CUE PF02845.16 CDJ80333.1 - 4.6e-10 39.0 0.0 9e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 CUE domain DMA PF03474.14 CDJ80333.1 - 0.0099 15.5 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 DMRTA motif DUF601 PF04642.12 CDJ80333.1 - 0.013 15.0 0.4 0.025 14.1 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Pyridoxal_deC PF00282.19 CDJ80334.1 - 3.2e-07 29.4 0.0 3.5e-07 29.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Pyridoxal_deC PF00282.19 CDJ80335.1 - 1.2e-38 132.8 0.1 1.7e-38 132.3 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 CDJ80335.1 - 0.017 14.3 0.0 0.043 13.0 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class I and II gag-asp_proteas PF13975.6 CDJ80336.1 - 0.0039 17.7 0.0 0.0096 16.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ80336.1 - 0.025 15.2 0.0 0.062 14.0 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 CDJ80336.1 - 4.9 7.4 14.6 2.1 8.6 2.6 3.0 2 1 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ80336.1 - 5.3 6.9 9.3 0.75 9.6 2.6 2.8 1 1 1 2 2 2 0 Zinc knuckle DUF1759 PF03564.15 CDJ80338.1 - 2.5e-15 56.7 0.1 6.6e-15 55.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) SprT-like PF10263.9 CDJ80339.1 - 2.3e-22 79.0 0.0 4.6e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 CDJ80339.1 - 0.00084 19.2 3.6 0.00084 19.2 3.6 2.1 2 0 0 2 2 2 1 SprT-like zinc ribbon domain Med4 PF10018.9 CDJ80341.1 - 0.026 14.2 0.7 0.03 14.0 0.7 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF5401 PF17380.2 CDJ80341.1 - 0.064 11.3 2.2 0.064 11.3 2.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) YabA PF06156.13 CDJ80341.1 - 0.064 13.9 0.7 0.081 13.6 0.7 1.3 1 1 0 1 1 1 0 Initiation control protein YabA Peptidase_S64 PF08192.11 CDJ80341.1 - 0.15 10.5 0.5 0.16 10.4 0.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF5339 PF17274.2 CDJ80341.1 - 0.35 11.8 5.3 0.52 11.2 5.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5339) FlaC_arch PF05377.11 CDJ80341.1 - 0.78 10.2 3.5 2.2 8.8 3.5 1.8 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 CDJ80341.1 - 1.5 8.7 6.5 1.2 9.0 5.1 1.6 1 1 0 1 1 1 0 Septum formation initiator ABC_tran PF00005.27 CDJ80342.1 - 6.3e-08 33.2 0.1 3.7e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 CDJ80342.1 - 0.00045 19.9 0.0 0.001 18.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3323 PF11796.8 CDJ80342.1 - 0.0011 19.0 0.6 0.0013 18.7 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function N-terminus (DUF3323) SMC_N PF02463.19 CDJ80342.1 - 0.0073 15.8 0.9 0.011 15.1 0.0 1.7 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CDJ80342.1 - 0.01 15.6 0.9 0.03 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 CDJ80342.1 - 0.012 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CDJ80342.1 - 0.016 15.7 0.2 0.016 15.7 0.2 2.0 1 1 1 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CDJ80342.1 - 0.068 13.3 0.0 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase MukB PF04310.12 CDJ80342.1 - 0.12 12.2 0.4 0.76 9.5 0.0 2.1 1 1 0 2 2 2 0 MukB N-terminal NARP1 PF12569.8 CDJ80342.1 - 1.9 7.3 5.3 2 7.2 5.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Mito_carr PF00153.27 CDJ80343.1 - 7.4e-66 218.1 2.8 2.9e-23 81.6 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein RVT_1 PF00078.27 CDJ80345.1 - 6.1e-08 32.4 0.0 8.7e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GST_N_3 PF13417.6 CDJ80346.1 - 9.7e-19 67.6 0.0 2.3e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CDJ80346.1 - 4.4e-14 52.6 0.0 8.2e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDJ80346.1 - 8.9e-13 48.4 0.1 1.2e-11 44.7 0.1 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CDJ80346.1 - 2.7e-07 30.7 0.0 6e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDJ80346.1 - 1.1e-06 28.6 0.1 5.3e-06 26.4 0.3 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDJ80346.1 - 0.0081 16.3 0.0 0.018 15.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 CDJ80346.1 - 0.02 15.1 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin DUF4728 PF15860.5 CDJ80347.1 - 0.0038 17.9 15.5 0.0038 17.9 15.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4728) DUF2085 PF09858.9 CDJ80347.1 - 0.027 14.9 7.1 0.027 14.9 7.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) ACBP PF00887.19 CDJ80348.1 - 3.5e-24 84.8 0.1 6.8e-24 83.9 0.1 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein tRNA-synt_2 PF00152.20 CDJ80349.1 - 1.4e-68 231.3 0.0 1.9e-68 230.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) RNase_P_Rpp14 PF01900.19 CDJ80349.1 - 3.4e-16 59.4 0.0 6.6e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Rpp14/Pop5 family Spore_SspJ PF09575.10 CDJ80349.1 - 0.13 12.7 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 Small spore protein J (Spore_SspJ) Collagen PF01391.18 CDJ80350.1 - 7.6e-21 73.6 99.5 2.7e-10 39.9 31.1 4.8 3 2 0 4 4 4 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ80350.1 - 1.9e-12 47.1 0.1 2.4e-12 46.7 0.1 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain DUF3367 PF11847.8 CDJ80350.1 - 0.12 10.2 0.0 0.16 9.8 0.0 1.1 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase DUF5488 PF17590.2 CDJ80351.1 - 3.4 7.5 6.7 0.59 9.9 0.8 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5488) Lipase_3 PF01764.25 CDJ80352.1 - 7.5e-38 129.6 0.0 1.1e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 CDJ80352.1 - 0.0028 17.2 0.1 0.014 15.0 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 CDJ80352.1 - 0.0096 16.5 0.1 0.013 16.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDJ80352.1 - 0.071 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 CDJ80353.1 - 8.5e-38 129.4 0.0 1.2e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 CDJ80353.1 - 0.0016 18.1 1.9 0.022 14.3 0.4 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 CDJ80353.1 - 0.0025 18.5 0.1 0.0033 18.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDJ80353.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 CDJ80354.1 - 3.1e-38 130.8 0.0 4.2e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 CDJ80354.1 - 0.0027 17.3 0.3 0.0065 16.1 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 CDJ80354.1 - 0.0033 18.0 0.0 0.0054 17.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 CDJ80354.1 - 0.0078 16.2 0.1 0.017 15.1 0.1 1.5 1 1 0 1 1 1 1 Cutinase Hydrolase_4 PF12146.8 CDJ80354.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ80354.1 - 0.013 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2048 PF09752.9 CDJ80354.1 - 0.076 12.1 0.1 0.89 8.6 0.1 2.0 2 0 0 2 2 2 0 Abhydrolase domain containing 18 PGAP1 PF07819.13 CDJ80354.1 - 0.15 11.8 0.1 0.32 10.7 0.1 1.6 1 1 0 1 1 1 0 PGAP1-like protein Nfu_N PF08712.11 CDJ80355.1 - 1.6e-29 101.8 0.1 3.4e-29 100.7 0.0 1.6 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 CDJ80355.1 - 2.4e-28 98.1 0.1 3.7e-28 97.4 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain Ank_2 PF12796.7 CDJ80356.1 - 1.7e-120 393.8 24.7 1.9e-16 60.4 1.2 11.6 3 3 8 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ80356.1 - 6e-97 314.2 32.3 6e-06 26.5 0.1 20.9 20 0 0 20 20 20 17 Ankyrin repeat Ank_4 PF13637.6 CDJ80356.1 - 1e-92 303.4 12.4 2.3e-08 34.4 0.0 14.8 7 5 8 15 15 15 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ80356.1 - 4e-85 269.5 25.2 5.6e-05 23.2 0.0 21.2 21 0 0 21 21 21 17 Ankyrin repeat Ank_5 PF13857.6 CDJ80356.1 - 5.2e-72 237.0 33.3 1.7e-08 34.6 0.0 16.8 6 4 12 18 18 18 18 Ankyrin repeats (many copies) KH_1 PF00013.29 CDJ80356.1 - 5.2e-13 48.6 1.6 1.2e-12 47.4 1.6 1.7 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 CDJ80356.1 - 0.0012 18.6 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 CDJ80356.1 - 0.017 15.0 0.1 0.07 13.0 0.1 2.1 1 0 0 1 1 1 0 KH domain Imm_superinfect PF14373.6 CDJ80356.1 - 0.16 11.9 0.0 61 3.7 0.0 4.1 5 0 0 5 5 5 0 Superinfection immunity protein Churchill PF06573.11 CDJ80357.1 - 0.011 16.0 0.3 0.033 14.5 0.1 1.9 1 1 0 1 1 1 0 Churchill protein Zn-ribbon_8 PF09723.10 CDJ80357.1 - 0.078 13.1 5.5 0.58 10.3 0.2 3.8 4 0 0 4 4 4 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 CDJ80357.1 - 0.31 11.0 2.4 0.56 10.2 0.3 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-H2C2_2 PF13465.6 CDJ80357.1 - 0.32 11.5 2.6 0.94 10.0 0.0 2.6 3 0 0 3 3 3 0 Zinc-finger double domain ADD_ATRX PF17981.1 CDJ80357.1 - 0.6 10.0 0.1 0.6 10.0 0.1 2.7 3 1 1 4 4 4 0 Cysteine Rich ADD domain zf-C2H2_4 PF13894.6 CDJ80357.1 - 0.97 10.4 12.9 1.7 9.7 0.7 3.4 4 0 0 4 4 4 0 C2H2-type zinc finger MFS_1 PF07690.16 CDJ80358.1 - 4.3e-38 131.1 30.9 8.7e-38 130.1 27.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Init_tRNA_PT PF04179.12 CDJ80358.1 - 0.18 12.1 0.8 8.6 6.7 0.0 2.8 2 1 0 2 2 2 0 Rit1 DUSP-like domain ASC PF00858.24 CDJ80360.1 - 2.6e-20 72.8 0.5 4e-20 72.2 0.5 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF5537 PF17690.1 CDJ80360.1 - 0.065 12.9 0.4 0.19 11.4 0.2 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5537) DUF4950 PF16308.5 CDJ80360.1 - 0.18 11.8 0.1 0.18 11.8 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4950) GRDP-like PF07173.12 CDJ80361.1 - 7.7e-51 172.5 2.7 4.9e-39 134.2 1.4 2.8 1 1 2 3 3 3 2 Glycine-rich domain-containing protein-like Mito_carr PF00153.27 CDJ80362.1 - 1e-14 54.2 0.2 1.1e-14 54.1 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein DOMON PF03351.17 CDJ80364.1 - 3.6e-15 56.3 0.1 5e-15 55.8 0.1 1.2 1 0 0 1 1 1 1 DOMON domain CDH-cyt PF16010.5 CDJ80364.1 - 0.16 11.7 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Cytochrome domain of cellobiose dehydrogenase I-set PF07679.16 CDJ80366.1 - 1.6e-35 121.0 0.1 2e-11 43.8 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ80366.1 - 4.5e-34 116.9 1.1 1.7e-13 51.0 0.1 3.4 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 CDJ80366.1 - 2.9e-23 81.8 0.0 1.6e-07 31.4 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 CDJ80366.1 - 4.4e-16 59.0 0.1 6.7e-08 32.8 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 CDJ80366.1 - 5.2e-13 49.1 0.3 0.0001 22.4 0.0 4.6 3 2 1 4 4 4 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDJ80366.1 - 2e-06 27.7 0.1 0.0031 17.5 0.0 3.1 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 CDJ80366.1 - 0.00012 22.4 0.0 0.03 14.7 0.0 3.4 3 1 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 CDJ80366.1 - 0.0002 21.3 0.0 2.5 8.2 0.0 4.0 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain V-set_CD47 PF08204.11 CDJ80366.1 - 0.00083 19.3 0.0 0.86 9.6 0.0 3.3 3 1 0 3 3 3 1 CD47 immunoglobulin-like domain Adeno_E3_CR1 PF02440.15 CDJ80366.1 - 0.0016 18.1 0.0 4.8 7.0 0.0 3.3 3 0 0 3 3 3 1 Adenovirus E3 region protein CR1 fn3 PF00041.21 CDJ80366.1 - 0.0032 17.8 0.3 0.012 15.9 0.1 2.1 2 0 0 2 2 2 1 Fibronectin type III domain YnfE PF17452.2 CDJ80367.1 - 0.22 11.8 0.2 0.22 11.8 0.2 2.7 3 1 0 3 3 3 0 Uncharacterized YnfE-like RecG_N PF17190.4 CDJ80367.1 - 0.31 11.8 4.1 7.4 7.4 0.2 2.5 2 1 1 3 3 3 0 RecG N-terminal helical domain CN_hydrolase PF00795.22 CDJ80369.1 - 4.9e-62 209.6 0.0 6.3e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase HIT PF01230.23 CDJ80369.1 - 4e-22 78.8 0.2 9.4e-22 77.6 0.2 1.6 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CDJ80369.1 - 1.4e-07 32.0 0.1 4.1e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CN_hydrolase PF00795.22 CDJ80370.1 - 1.9e-69 233.9 0.0 2.4e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase HIT PF01230.23 CDJ80370.1 - 1.5e-21 76.9 0.6 2.9e-21 76.0 0.6 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CDJ80370.1 - 2e-07 31.5 0.1 4.5e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GalP_UDP_tr_C PF02744.17 CDJ80370.1 - 0.095 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF1279 PF06916.13 CDJ80371.1 - 9.3e-20 71.0 1.7 1.5e-19 70.3 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) PIG-P PF08510.12 CDJ80371.1 - 0.069 13.1 4.6 0.047 13.6 2.6 2.0 1 1 1 2 2 2 0 PIG-P TRAP-delta PF05404.12 CDJ80372.1 - 2.8e-51 173.3 1.5 3.3e-51 173.0 1.5 1.0 1 0 0 1 1 1 1 Translocon-associated protein, delta subunit precursor (TRAP-delta) CAF1 PF04857.20 CDJ80373.1 - 1.3e-21 77.1 0.3 1.4e-12 47.5 0.0 2.4 2 1 0 2 2 2 2 CAF1 family ribonuclease 5_nucleotid PF05761.14 CDJ80374.1 - 1.9e-138 462.2 0.1 2.7e-138 461.7 0.1 1.2 1 0 0 1 1 1 1 5' nucleotidase family zf-C2H2_jaz PF12171.8 CDJ80374.1 - 1.3e-08 34.9 2.4 3.7e-08 33.4 2.4 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding HAD_2 PF13419.6 CDJ80374.1 - 0.0013 18.8 0.0 0.027 14.6 0.0 2.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CDJ80374.1 - 0.14 12.3 0.0 0.61 10.2 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Autophagy_N PF03986.13 CDJ80375.1 - 2.9e-48 163.3 0.1 4.7e-48 162.6 0.1 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 CDJ80375.1 - 1.8e-17 63.6 1.4 4.8e-17 62.3 1.1 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 CDJ80375.1 - 3.7e-15 55.1 1.8 4e-15 55.0 0.6 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein C-terminal Innate_immun PF12782.7 CDJ80375.1 - 0.12 11.9 1.5 0.18 11.2 1.5 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Ldl_recept_b PF00058.17 CDJ80376.1 - 3.2e-21 75.5 0.6 1.1e-11 45.0 0.2 3.3 3 0 0 3 3 3 2 Low-density lipoprotein receptor repeat class B Arylesterase PF01731.20 CDJ80376.1 - 0.011 15.9 0.1 1.2 9.4 0.0 2.1 2 0 0 2 2 2 0 Arylesterase AAA_21 PF13304.6 CDJ80377.1 - 0.0053 16.6 0.0 0.0094 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 CDJ80377.1 - 0.057 14.1 0.0 0.11 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) CobN-Mg_chel PF02514.16 CDJ80377.1 - 0.26 9.0 0.0 0.28 8.9 0.0 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase AMP-binding PF00501.28 CDJ80378.1 - 4.3e-37 127.7 0.0 5e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Motile_Sperm PF00635.26 CDJ80379.1 - 1.5e-26 92.4 0.1 1.5e-26 92.4 0.1 2.8 1 1 1 2 2 1 1 MSP (Major sperm protein) domain ASH PF15780.5 CDJ80379.1 - 0.00018 21.6 0.0 0.00035 20.7 0.0 1.4 1 1 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PPP4R2 PF09184.11 CDJ80379.1 - 0.039 13.6 28.4 0.045 13.3 28.4 1.2 1 0 0 1 1 1 0 PPP4R2 SAPS PF04499.15 CDJ80379.1 - 0.052 12.3 13.1 0.045 12.5 13.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 CDJ80379.1 - 0.23 10.4 9.7 0.21 10.5 9.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SpoIIIAH PF12685.7 CDJ80379.1 - 0.3 10.9 19.9 0.5 10.2 19.9 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein CDC27 PF09507.10 CDJ80379.1 - 0.61 9.4 36.6 0.72 9.2 36.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 VIR_N PF15912.5 CDJ80379.1 - 1.2 8.7 16.8 1.5 8.4 16.8 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal DAG_kinase_N PF14513.6 CDJ80379.1 - 1.9 8.7 17.0 3 8.0 17.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus DUF4746 PF15928.5 CDJ80379.1 - 2 7.8 26.2 2.7 7.4 26.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Paramyxo_ncap PF00973.19 CDJ80379.1 - 2.3 7.0 14.2 2.5 6.9 14.2 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Neur_chan_memb PF02932.16 CDJ80379.1 - 2.5 8.1 9.0 2.9 7.9 9.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF5308 PF17233.2 CDJ80379.1 - 2.6 8.3 4.4 3.6 7.8 4.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5308) SID-1_RNA_chan PF13965.6 CDJ80379.1 - 3.2 6.1 4.9 2.9 6.2 4.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF908 PF06012.12 CDJ80379.1 - 6.6 6.0 7.8 6.9 6.0 7.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Presenilin PF01080.17 CDJ80379.1 - 6.9 5.3 20.6 8 5.1 20.6 1.1 1 0 0 1 1 1 0 Presenilin Rad21_Rec8_N PF04825.13 CDJ80380.1 - 8.6e-18 64.5 0.0 1.7e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CDJ80380.1 - 4.1e-09 35.6 0.0 8.7e-09 34.5 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Solute_trans_a PF03619.16 CDJ80381.1 - 6.4e-20 71.8 25.2 8.8e-20 71.3 25.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha EOS1 PF12326.8 CDJ80381.1 - 1.4 8.8 9.6 3.3 7.6 8.3 2.2 2 0 0 2 2 2 0 N-glycosylation protein RRM_1 PF00076.22 CDJ80382.1 - 1.9e-59 197.4 0.4 3.8e-22 77.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ80382.1 - 1e-09 38.1 0.0 1.1e-05 25.0 0.0 3.2 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ80382.1 - 1.8e-07 30.9 0.0 0.00021 21.1 0.0 2.8 3 0 0 3 3 3 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 CDJ80382.1 - 3.6e-05 23.8 0.0 0.026 14.6 0.0 3.2 3 0 0 3 3 3 1 Limkain b1 PHM7_cyt PF14703.6 CDJ80382.1 - 5e-05 23.6 0.0 0.013 15.7 0.0 3.4 3 0 0 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 CDJ80382.1 - 0.00011 22.3 1.3 0.39 10.9 0.1 4.2 3 2 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CDJ80382.1 - 0.0013 18.7 0.7 4.8 7.3 0.1 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CDJ80382.1 - 0.014 15.4 0.0 12 6.0 0.0 3.1 3 0 0 3 3 3 0 RNA binding motif SET_assoc PF11767.8 CDJ80382.1 - 0.1 12.3 0.2 12 5.6 0.0 2.6 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated Pes-10 PF07149.11 CDJ80382.1 - 0.24 10.4 0.0 0.33 10.0 0.0 1.1 1 0 0 1 1 1 0 Pes-10 DUF5527 PF17665.1 CDJ80383.1 - 0.006 16.1 0.1 0.0099 15.4 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5527) efThoc1 PF11957.8 CDJ80384.1 - 1.7e-96 323.9 15.6 2.3e-96 323.4 15.6 1.2 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Death PF00531.22 CDJ80384.1 - 1.5e-05 25.0 1.9 3.2e-05 24.0 0.3 2.3 2 0 0 2 2 2 1 Death domain ASFV_J13L PF05568.11 CDJ80384.1 - 0.081 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein WD40 PF00400.32 CDJ80385.1 - 2.4e-31 107.3 9.6 6.4e-06 26.8 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ80385.1 - 1.4e-06 28.5 0.2 0.92 9.8 0.0 4.7 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDJ80385.1 - 0.0021 16.8 0.3 0.34 9.5 0.1 3.1 2 1 1 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 CDJ80385.1 - 0.0022 17.4 0.0 0.22 10.8 0.0 2.3 1 1 1 2 2 2 2 WD40-like domain Cytochrom_D1 PF02239.16 CDJ80385.1 - 0.061 11.8 0.1 0.17 10.4 0.0 1.7 1 1 1 2 2 2 0 Cytochrome D1 heme domain Nucleopor_Nup85 PF07575.13 CDJ80386.1 - 5.3e-74 249.8 1.4 8.6e-74 249.1 1.4 1.3 1 0 0 1 1 1 1 Nup85 Nucleoporin RBD-FIP PF09457.10 CDJ80386.1 - 4.7e-06 26.4 2.0 4.7e-06 26.4 2.0 2.1 2 0 0 2 2 2 1 FIP domain Acyl-CoA_dh_N PF02771.16 CDJ80387.1 - 9.1e-26 90.7 0.1 1.1e-25 90.4 0.1 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CDJ80387.1 - 1.1e-11 44.8 0.0 1.9e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 CDJ80388.1 - 1.1e-16 61.4 0.0 1.5e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 CDJ80388.1 - 1e-05 25.8 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CDJ80388.1 - 0.0041 17.3 0.0 0.0071 16.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AAA_11 PF13086.6 CDJ80389.1 - 3.7e-09 36.8 0.0 7.1e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ80389.1 - 1e-07 31.9 0.0 1.8e-05 24.5 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 CDJ80389.1 - 7.2e-05 22.5 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ80389.1 - 0.00072 19.9 0.0 0.0023 18.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CDJ80389.1 - 0.0036 16.6 0.0 0.0055 16.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 CDJ80389.1 - 0.013 15.5 0.0 0.038 14.0 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 CDJ80389.1 - 0.026 14.4 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Helicase DEAD PF00270.29 CDJ80389.1 - 0.031 14.0 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Sigma54_activat PF00158.26 CDJ80389.1 - 0.043 13.5 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 CDJ80389.1 - 0.058 12.8 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein DUF2791 PF10923.8 CDJ80389.1 - 0.15 10.8 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) ATPase PF06745.13 CDJ80389.1 - 0.24 10.7 0.0 0.42 9.9 0.0 1.3 1 0 0 1 1 1 0 KaiC Acyl-CoA_dh_1 PF00441.24 CDJ80390.1 - 7.7e-13 48.9 0.0 9.1e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 CDJ80390.1 - 6.7e-09 36.1 0.0 7.8e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AAA_12 PF13087.6 CDJ80391.1 - 2.3e-25 89.4 0.0 3.9e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ80391.1 - 6.5e-09 36.0 0.0 1.2e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ80391.1 - 1.6e-07 31.3 0.0 2.9e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CDJ80391.1 - 7.6e-05 23.1 0.0 0.00041 20.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 CDJ80391.1 - 0.00072 18.9 0.1 0.0062 15.8 0.1 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CDJ80391.1 - 0.0013 18.7 0.0 0.32 10.9 0.0 2.7 3 0 0 3 3 3 1 NACHT domain DEAD PF00270.29 CDJ80391.1 - 0.0078 16.0 0.0 0.026 14.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Sigma54_activat PF00158.26 CDJ80391.1 - 0.014 15.1 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 CDJ80391.1 - 0.014 15.4 0.0 0.031 14.3 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 CDJ80391.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Helicase PhoH PF02562.16 CDJ80391.1 - 0.018 14.5 0.1 0.035 13.6 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 CDJ80391.1 - 0.021 14.2 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 KaiC DUF2791 PF10923.8 CDJ80391.1 - 0.036 12.9 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Acyl-CoA_dh_1 PF00441.24 CDJ80392.1 - 7.4e-21 74.9 0.1 8.1e-21 74.8 0.1 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 CDJ80392.1 - 3.7e-09 37.0 0.0 4e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AAA_12 PF13087.6 CDJ80393.1 - 8.7e-26 90.8 0.0 1.8e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ80393.1 - 2.9e-07 30.6 0.0 6.8e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ80393.1 - 3.1e-07 30.3 0.0 2.9e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CDJ80393.1 - 0.00048 20.5 0.1 0.0068 16.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CDJ80393.1 - 0.002 17.4 0.2 0.013 14.8 0.1 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 CDJ80393.1 - 0.029 14.1 0.0 0.071 12.9 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase ResIII PF04851.15 CDJ80393.1 - 0.031 14.3 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 CDJ80393.1 - 0.053 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Helicase Sigma54_activat PF00158.26 CDJ80393.1 - 0.075 12.7 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 CDJ80393.1 - 0.079 12.4 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 CDJ80393.1 - 0.12 12.3 1.2 1 9.2 0.0 2.9 3 1 0 3 3 3 0 NACHT domain ATPase PF06745.13 CDJ80393.1 - 0.24 10.7 0.0 0.46 9.8 0.0 1.4 1 0 0 1 1 1 0 KaiC zf-C2H2 PF00096.26 CDJ80394.1 - 3.2e-13 49.4 22.1 2e-05 24.8 3.2 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ80394.1 - 1.5e-12 47.3 8.4 2.8e-09 37.0 0.8 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDJ80394.1 - 2e-08 34.3 21.6 0.00065 20.3 2.3 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ80394.1 - 0.096 13.0 4.0 1.7 9.0 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDJ80394.1 - 0.27 11.7 6.7 0.52 10.8 0.5 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 CDJ80394.1 - 0.99 9.2 15.1 2.4 8.0 0.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain FOXP-CC PF16159.5 CDJ80394.1 - 4.3 8.1 7.2 4.3 8.0 1.8 2.7 1 1 2 3 3 3 0 FOXP coiled-coil domain HABP4_PAI-RBP1 PF04774.15 CDJ80395.1 - 1.6e-17 64.4 3.6 1.6e-17 64.4 3.6 2.6 2 0 0 2 2 2 1 Hyaluronan / mRNA binding family IHABP4_N PF16174.5 CDJ80395.1 - 0.001 19.7 9.8 0.001 19.7 9.8 2.8 1 1 1 2 2 2 1 Intracellular hyaluronan-binding protein 4 N-terminal FoP_duplication PF13865.6 CDJ80395.1 - 0.02 15.4 1.8 0.02 15.4 1.8 5.4 3 2 1 4 4 4 0 C-terminal duplication domain of Friend of PRMT1 T4_Rnl2_C PF18043.1 CDJ80396.1 - 0.029 14.5 0.2 0.046 13.8 0.2 1.3 1 0 0 1 1 1 0 T4 RNA ligase 2 C-terminal RVT_1 PF00078.27 CDJ80399.1 - 1.6e-16 60.5 0.0 2.3e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CDJ80400.1 - 0.0056 16.2 0.0 0.0067 16.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_Tnp_Tc3_2 PF01498.18 CDJ80401.1 - 1.7e-25 89.0 0.5 3.7e-25 88.0 0.5 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 CDJ80401.1 - 5.7e-12 45.6 0.0 1.1e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 CDJ80401.1 - 1.6e-05 25.4 0.8 1.6e-05 25.4 0.8 3.1 2 1 1 3 3 3 1 Homeodomain-like domain PAX PF00292.18 CDJ80401.1 - 0.00022 21.2 0.2 0.00035 20.5 0.2 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_24 PF13412.6 CDJ80401.1 - 0.022 14.3 1.0 0.63 9.7 0.1 2.9 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 CDJ80401.1 - 0.21 11.4 0.1 0.21 11.4 0.1 3.0 4 0 0 4 4 4 0 Homeodomain-like domain MLVIN_C PF18697.1 CDJ80402.1 - 0.052 13.7 0.0 0.099 12.8 0.0 1.5 1 1 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Nup54_57_C PF18570.1 CDJ80402.1 - 0.52 9.9 1.9 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain SAM_1 PF00536.30 CDJ80404.1 - 3.7e-10 40.1 0.1 1.2e-06 28.8 0.0 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CDJ80404.1 - 4.3e-05 23.6 0.0 0.0015 18.6 0.0 2.7 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) Tropomyosin PF00261.20 CDJ80405.1 - 0.013 14.9 19.6 0.031 13.6 19.6 1.6 1 0 0 1 1 1 0 Tropomyosin LMBR1 PF04791.16 CDJ80405.1 - 0.075 11.9 3.0 0.11 11.4 3.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein FapA PF03961.13 CDJ80405.1 - 0.14 10.8 8.6 0.15 10.6 7.1 1.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A YjbH PF06082.11 CDJ80405.1 - 0.17 10.7 5.7 0.2 10.4 5.7 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH STN1_2 PF09170.10 CDJ80405.1 - 0.51 10.5 9.5 0.17 12.1 6.1 1.9 2 0 0 2 2 2 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Prominin PF05478.11 CDJ80405.1 - 0.53 8.2 8.3 0.93 7.4 8.3 1.3 1 0 0 1 1 1 0 Prominin SpoOE-like PF09388.10 CDJ80405.1 - 2.6 8.0 8.3 0.64 10.0 0.3 2.9 3 0 0 3 3 3 0 Spo0E like sporulation regulatory protein HALZ PF02183.18 CDJ80405.1 - 3.5 7.9 12.5 0.14 12.4 1.7 3.6 2 1 2 4 4 4 0 Homeobox associated leucine zipper Phage_GPO PF05929.11 CDJ80405.1 - 4.6 6.8 13.6 9.3 5.8 13.6 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase GAS PF13851.6 CDJ80405.1 - 5.4 6.3 25.4 1.5 8.2 8.2 2.8 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.8 CDJ80406.1 - 0.14 9.7 10.1 0.012 13.2 2.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) FliJ PF02050.16 CDJ80406.1 - 0.28 11.4 16.8 0.06 13.6 3.1 3.5 4 0 0 4 4 4 0 Flagellar FliJ protein ALMT PF11744.8 CDJ80406.1 - 0.34 9.7 2.6 0.51 9.1 2.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter GAS PF13851.6 CDJ80406.1 - 2.3 7.5 16.1 0.065 12.6 0.9 2.7 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding EspB PF05802.11 CDJ80406.1 - 2.6 8.0 7.0 0.76 9.7 1.5 2.2 2 0 0 2 2 2 0 Enterobacterial EspB protein Med9 PF07544.13 CDJ80406.1 - 2.8 8.1 12.7 6.9 6.8 1.6 3.9 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 YojJ PF10372.9 CDJ80406.1 - 6.3 7.0 6.7 29 4.8 0.2 3.3 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus SAM_1 PF00536.30 CDJ80407.1 - 3.7e-10 40.1 0.1 1.2e-06 28.8 0.0 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CDJ80407.1 - 4.3e-05 23.6 0.0 0.0015 18.6 0.0 2.7 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) Tropomyosin PF00261.20 CDJ80408.1 - 0.013 14.9 19.6 0.031 13.6 19.6 1.6 1 0 0 1 1 1 0 Tropomyosin LMBR1 PF04791.16 CDJ80408.1 - 0.075 11.9 3.0 0.11 11.4 3.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein FapA PF03961.13 CDJ80408.1 - 0.14 10.8 8.6 0.15 10.6 7.1 1.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A YjbH PF06082.11 CDJ80408.1 - 0.17 10.7 5.7 0.2 10.4 5.7 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH STN1_2 PF09170.10 CDJ80408.1 - 0.51 10.5 9.5 0.17 12.1 6.1 1.9 2 0 0 2 2 2 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Prominin PF05478.11 CDJ80408.1 - 0.53 8.2 8.3 0.93 7.4 8.3 1.3 1 0 0 1 1 1 0 Prominin SpoOE-like PF09388.10 CDJ80408.1 - 2.6 8.0 8.3 0.64 10.0 0.3 2.9 3 0 0 3 3 3 0 Spo0E like sporulation regulatory protein HALZ PF02183.18 CDJ80408.1 - 3.5 7.9 12.5 0.14 12.4 1.7 3.6 2 1 2 4 4 4 0 Homeobox associated leucine zipper Phage_GPO PF05929.11 CDJ80408.1 - 4.6 6.8 13.6 9.3 5.8 13.6 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase GAS PF13851.6 CDJ80408.1 - 5.4 6.3 25.4 1.5 8.2 8.2 2.8 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DAP PF15228.6 CDJ80409.1 - 4.1e-16 60.0 4.2 5.5e-16 59.5 4.2 1.2 1 0 0 1 1 1 1 Death-associated protein Glutaredoxin2_C PF04399.13 CDJ80410.1 - 0.14 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Cys_rich_VLP PF14194.6 CDJ80410.1 - 2.6 8.2 5.8 11 6.2 0.9 2.8 2 1 0 3 3 3 0 Cysteine-rich VLP Bromodomain PF00439.25 CDJ80411.1 - 5.8e-108 353.2 14.2 3.5e-20 71.8 0.0 6.6 6 0 0 6 6 6 6 Bromodomain BAH PF01426.18 CDJ80411.1 - 6.2e-29 100.3 0.1 9.4e-14 51.3 0.0 2.9 2 0 0 2 2 2 2 BAH domain HMG_box PF00505.19 CDJ80411.1 - 7.3e-12 45.5 1.9 3.6e-11 43.3 0.3 2.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ80411.1 - 1.1e-07 32.4 2.4 1.3e-07 32.1 0.3 2.3 2 0 0 2 2 2 1 HMG-box domain zf-C2H2_aberr PF17017.5 CDJ80411.1 - 0.00014 22.1 0.6 0.00014 22.1 0.6 1.9 2 0 0 2 2 2 1 Aberrant zinc-finger FOXP-CC PF16159.5 CDJ80411.1 - 0.017 15.7 2.9 0.18 12.4 0.5 3.0 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 CDJ80411.1 - 0.034 15.0 4.2 1.9 9.5 0.4 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4690 PF15756.5 CDJ80412.1 - 0.17 12.5 0.2 0.29 11.8 0.2 1.4 1 0 0 1 1 1 0 Small Novel Rich in Cartilage IPK PF03770.16 CDJ80413.1 - 8.2e-48 162.9 0.0 1e-47 162.6 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase Herpes_UL73 PF03554.13 CDJ80413.1 - 0.098 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein PDZ PF00595.24 CDJ80414.1 - 5e-20 71.6 0.2 7.9e-20 71.0 0.2 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDJ80414.1 - 1e-07 31.6 0.1 2.5e-07 30.4 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PH_17 PF18012.1 CDJ80414.1 - 2.6e-07 30.2 0.0 6.1e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 PH domain PDZ_2 PF13180.6 CDJ80414.1 - 3.4e-05 24.1 0.6 8.5e-05 22.8 0.4 1.8 2 0 0 2 2 2 1 PDZ domain Laminin_G_2 PF02210.24 CDJ80414.1 - 0.0068 17.0 0.0 0.011 16.3 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 CDJ80414.1 - 0.11 12.8 0.0 0.16 12.2 0.0 1.4 1 1 0 1 1 1 0 Laminin G domain PH PF00169.29 CDJ80415.1 - 0.0026 18.2 0.0 0.0034 17.9 0.0 1.2 1 0 0 1 1 1 1 PH domain Fcf1 PF04900.12 CDJ80416.1 - 6.6e-37 125.9 0.7 1.1e-36 125.2 0.7 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 CDJ80416.1 - 1.5e-09 38.2 0.2 3.2e-09 37.1 0.0 1.6 2 0 0 2 2 2 1 PIN like domain Dynein_light PF01221.18 CDJ80416.1 - 0.045 14.1 0.0 0.096 13.0 0.0 1.5 1 0 0 1 1 1 0 Dynein light chain type 1 CHCH PF06747.13 CDJ80417.1 - 1.6e-10 40.8 2.9 1.6e-10 40.8 2.9 1.8 2 0 0 2 2 2 1 CHCH domain Band_7 PF01145.25 CDJ80418.1 - 9.9e-31 107.1 0.4 9.9e-31 107.1 0.4 1.8 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 CDJ80418.1 - 1.2e-26 92.5 1.9 2.4e-26 91.6 0.7 2.2 2 0 0 2 2 2 1 C-terminal region of band_7 Band_7_1 PF13421.6 CDJ80418.1 - 0.00044 20.0 0.2 0.00075 19.3 0.2 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family EF-hand_7 PF13499.6 CDJ80419.1 - 2.4e-14 53.5 11.8 3.5e-12 46.6 5.9 2.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CDJ80419.1 - 2.9e-09 35.8 12.5 8e-05 21.9 0.1 3.9 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CDJ80419.1 - 4.5e-07 29.3 11.0 0.0015 18.3 1.3 3.9 4 0 0 4 4 4 3 EF-hand domain SPARC_Ca_bdg PF10591.9 CDJ80419.1 - 0.0026 18.0 0.9 0.0049 17.2 0.4 1.7 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 CDJ80419.1 - 0.028 14.2 11.5 0.2 11.5 3.6 3.3 2 1 0 2 2 2 0 EF-hand domain pair PMBR PF09373.10 CDJ80419.1 - 0.14 12.4 0.7 7.7 6.9 0.0 3.7 5 0 0 5 5 5 0 Pseudomurein-binding repeat DUF758 PF05527.11 CDJ80420.1 - 1.9e-43 148.6 11.3 2.3e-43 148.3 11.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF758) Pico_P2B PF01552.17 CDJ80420.1 - 0.018 15.2 1.2 0.073 13.2 0.3 2.2 1 1 0 2 2 2 0 Picornavirus 2B protein DUF592 PF04574.13 CDJ80420.1 - 0.029 14.1 5.0 0.019 14.8 3.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF592) STAS PF01740.21 CDJ80421.1 - 0.12 12.0 0.2 1.9 8.1 0.0 2.0 1 1 1 2 2 2 0 STAS domain Ion_trans_2 PF07885.16 CDJ80423.1 - 9.2e-34 115.3 25.5 2.7e-17 62.5 1.7 2.8 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CDJ80423.1 - 2e-10 40.3 16.7 6.9e-06 25.5 0.5 2.2 2 0 0 2 2 2 2 Ion transport protein DUF2157 PF09925.9 CDJ80423.1 - 0.02 14.7 0.7 1.2 9.0 0.0 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) Lig_chan PF00060.26 CDJ80423.1 - 0.78 9.6 6.6 0.25 11.2 0.2 2.6 2 2 0 3 3 3 0 Ligand-gated ion channel Claudin_2 PF13903.6 CDJ80424.1 - 7.9e-08 32.3 6.8 1.9e-07 31.1 6.8 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Sulfate_transp PF00916.20 CDJ80424.1 - 0.014 14.2 1.9 0.83 8.3 0.1 2.1 2 0 0 2 2 2 0 Sulfate permease family YtpI PF14007.6 CDJ80424.1 - 0.042 14.0 1.0 0.042 14.0 1.0 2.1 2 0 0 2 2 2 0 YtpI-like protein DUF3285 PF11688.8 CDJ80424.1 - 0.048 13.6 3.1 0.45 10.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) ABC_export PF16962.5 CDJ80424.1 - 0.13 10.7 7.1 0.013 14.0 1.2 1.9 2 0 0 2 2 2 0 Putative ABC exporter LrgA PF03788.14 CDJ80424.1 - 0.16 11.9 0.2 0.16 11.9 0.2 2.2 2 0 0 2 2 2 0 LrgA family GT87 PF09594.10 CDJ80424.1 - 0.17 11.6 15.7 3.9 7.1 4.1 2.2 1 1 1 2 2 2 0 Glycosyltransferase family 87 Phage_holin_3_6 PF07332.11 CDJ80424.1 - 0.62 10.1 8.3 4 7.5 0.1 2.8 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III PMP22_Claudin PF00822.20 CDJ80424.1 - 1.1 9.1 8.3 0.76 9.6 4.4 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family DUF3493 PF11998.8 CDJ80424.1 - 1.4 9.2 6.2 17 5.7 0.0 3.3 3 1 0 3 3 3 0 Low psii accumulation1 / Rep27 MFS_1 PF07690.16 CDJ80425.1 - 4.1e-19 68.7 32.0 1.3e-16 60.4 10.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0767 PF15990.5 CDJ80425.1 - 0.16 12.2 1.3 1.5 9.0 0.2 3.0 3 0 0 3 3 3 0 UPF0767 family TMEM132D_C PF15706.5 CDJ80426.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term V_ATPase_I PF01496.19 CDJ80426.1 - 0.017 13.1 0.0 0.019 12.9 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMEM100 PF16311.5 CDJ80426.1 - 0.057 13.0 0.1 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 Transmembrane protein 100 DUF5305 PF17231.2 CDJ80426.1 - 0.059 12.8 0.0 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) TMEM154 PF15102.6 CDJ80426.1 - 0.096 12.6 0.0 0.31 10.9 0.0 1.7 1 1 0 2 2 2 0 TMEM154 protein family LST1 PF05083.13 CDJ80426.1 - 0.13 12.6 0.9 0.3 11.4 0.9 1.7 1 1 0 1 1 1 0 LST-1 protein LapA_dom PF06305.11 CDJ80426.1 - 0.61 9.9 5.5 1.9 8.4 5.5 1.8 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain UPF0542 PF15086.6 CDJ80426.1 - 7.7 6.5 9.3 2.2 8.3 0.2 2.4 1 1 1 2 2 2 0 Uncharacterised protein family UPF0542 Exo_endo_phos_2 PF14529.6 CDJ80427.1 - 1.3e-06 28.3 0.0 2.6e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ80427.1 - 0.0013 18.3 0.1 0.0019 17.8 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2681 PF10883.8 CDJ80429.1 - 0.015 15.7 2.5 0.025 15.0 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) EMC3_TMCO1 PF01956.16 CDJ80429.1 - 0.017 14.9 0.7 0.022 14.5 0.7 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like HemY_N PF07219.13 CDJ80429.1 - 0.027 14.7 0.1 0.04 14.1 0.1 1.2 1 0 0 1 1 1 0 HemY protein N-terminus FAM163 PF15069.6 CDJ80429.1 - 0.035 14.6 0.0 0.054 13.9 0.0 1.3 1 0 0 1 1 1 0 FAM163 family Ion_trans_2 PF07885.16 CDJ80429.1 - 0.1 12.6 1.0 0.15 12.0 1.0 1.3 1 0 0 1 1 1 0 Ion channel Baculo_11_kDa PF06143.11 CDJ80429.1 - 0.14 11.8 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family LST1 PF05083.13 CDJ80429.1 - 0.15 12.3 2.3 0.5 10.7 1.1 2.3 2 1 0 2 2 2 0 LST-1 protein SID-1_RNA_chan PF13965.6 CDJ80429.1 - 0.2 10.1 0.0 0.22 9.9 0.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TIL PF01826.17 CDJ80430.1 - 2.1e-14 53.5 47.9 1.8e-09 37.7 19.4 5.7 4 1 1 5 5 5 2 Trypsin Inhibitor like cysteine rich domain TMEM154 PF15102.6 CDJ80431.1 - 2.2e-05 24.4 1.1 8.9e-05 22.4 0.0 2.1 1 1 1 2 2 2 1 TMEM154 protein family Shisa PF13908.6 CDJ80431.1 - 0.0012 19.1 0.0 0.0032 17.7 0.0 1.6 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator MAP17 PF15807.5 CDJ80431.1 - 0.0038 17.4 1.8 0.0044 17.2 0.7 1.6 1 1 1 2 2 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 EMC3_TMCO1 PF01956.16 CDJ80431.1 - 0.0086 15.8 0.4 0.018 14.8 0.4 1.5 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like LST1 PF05083.13 CDJ80431.1 - 0.011 15.9 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 LST-1 protein EphA2_TM PF14575.6 CDJ80431.1 - 0.012 16.4 0.0 0.04 14.8 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain V_ATPase_I PF01496.19 CDJ80431.1 - 0.013 13.5 0.1 0.016 13.2 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM176 PF14851.6 CDJ80431.1 - 0.017 14.8 0.1 0.073 12.7 0.0 2.0 2 0 0 2 2 2 0 FAM176 family ATP-synt_B PF00430.18 CDJ80431.1 - 0.019 15.1 1.5 0.032 14.3 1.5 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Orf78 PF06024.12 CDJ80431.1 - 0.021 15.1 0.8 0.094 13.0 0.0 2.1 1 1 1 2 2 2 0 Orf78 (ac78) MSC PF09402.10 CDJ80431.1 - 0.021 14.3 0.1 0.027 13.9 0.1 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain AP3D1 PF06375.11 CDJ80431.1 - 0.023 14.9 4.2 0.18 12.0 2.6 2.1 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Vpu PF00558.19 CDJ80431.1 - 0.024 14.4 7.3 0.055 13.3 7.3 1.6 1 1 0 1 1 1 0 Vpu protein Phage_holin_3_6 PF07332.11 CDJ80431.1 - 0.024 14.7 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Peptidase_S49_N PF08496.10 CDJ80431.1 - 0.026 14.6 0.8 0.062 13.4 0.8 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4834 PF16118.5 CDJ80431.1 - 0.044 14.7 0.4 0.044 14.7 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) Herpes_gE PF02480.16 CDJ80431.1 - 0.054 12.2 0.0 0.077 11.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF2561 PF10812.8 CDJ80431.1 - 0.065 13.3 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Ctr PF04145.15 CDJ80431.1 - 0.095 13.3 0.1 0.2 12.3 0.0 1.5 2 0 0 2 2 1 0 Ctr copper transporter family DUF4446 PF14584.6 CDJ80431.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Nucleoside_tran PF01733.18 CDJ80431.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Nucleoside transporter DUF4381 PF14316.6 CDJ80431.1 - 0.19 12.0 0.0 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF4736 PF15883.5 CDJ80431.1 - 0.2 11.4 0.2 0.65 9.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) Protocadherin PF08374.11 CDJ80431.1 - 0.2 11.6 4.7 0.1 12.6 2.0 1.9 2 1 0 2 2 1 0 Protocadherin Baculo_11_kDa PF06143.11 CDJ80431.1 - 0.21 11.2 0.4 0.52 9.9 0.4 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family UPF0239 PF06783.11 CDJ80431.1 - 0.24 11.6 2.9 0.32 11.2 2.0 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0239) DUF1180 PF06679.12 CDJ80431.1 - 0.55 10.6 3.2 0.36 11.2 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) TMEM51 PF15345.6 CDJ80431.1 - 3.3 7.5 5.8 6.7 6.5 5.8 1.5 1 1 0 1 1 1 0 Transmembrane protein 51 Transposase_1 PF01359.18 CDJ80432.1 - 0.0049 16.7 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) Pkinase PF00069.25 CDJ80434.1 - 3.5e-39 134.7 0.0 5.2e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ80434.1 - 4.2e-27 95.1 0.0 1.6e-26 93.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ80434.1 - 0.00013 21.4 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CDJ80434.1 - 0.097 11.6 0.0 0.28 10.1 0.0 1.8 1 1 0 1 1 1 0 Haspin like kinase domain Myb_DNA-binding PF00249.31 CDJ80435.1 - 1.3e-15 57.3 0.2 3.5e-07 30.3 0.1 3.6 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ80435.1 - 6.4e-09 35.9 3.8 7.6e-06 26.1 0.9 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 CDJ80435.1 - 0.0063 16.7 0.9 2.5 8.4 0.1 2.9 2 0 0 2 2 2 2 SANT/Myb-like domain of DAMP1 FAM163 PF15069.6 CDJ80435.1 - 0.15 12.5 9.2 0.28 11.6 0.6 3.7 2 0 0 2 2 2 0 FAM163 family MOZART1 PF12554.8 CDJ80436.1 - 4.8e-05 23.0 0.1 6.4e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated COPIIcoated_ERV PF07970.12 CDJ80437.1 - 7.6e-75 251.6 0.1 1e-74 251.2 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CDJ80437.1 - 1.2e-27 96.1 0.1 3.5e-27 94.6 0.1 1.8 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) I-set PF07679.16 CDJ80438.1 - 1.9e-21 75.9 0.0 5.4e-13 48.8 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ80438.1 - 1.4e-20 73.7 0.1 1.3e-09 38.5 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 CDJ80438.1 - 4.3e-13 49.3 0.0 2e-06 27.9 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 CDJ80438.1 - 3.7e-12 46.4 0.1 4.3e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 CDJ80438.1 - 8.6e-05 22.5 0.0 0.095 12.8 0.0 2.4 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 CDJ80438.1 - 0.0037 17.4 0.0 0.14 12.4 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin V-set domain C1-set PF07654.15 CDJ80438.1 - 0.013 15.9 0.0 7.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin C1-set domain PKD_3 PF16820.5 CDJ80438.1 - 0.019 14.7 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 PKD-like domain Peptidase_C13 PF01650.18 CDJ80439.1 - 1.3e-24 87.1 0.3 1.6e-24 86.8 0.3 1.1 1 0 0 1 1 1 1 Peptidase C13 family LSM PF01423.22 CDJ80441.1 - 3.1e-16 58.8 0.5 4e-16 58.5 0.5 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CDJ80441.1 - 0.0077 15.9 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Hfq protein DUF681 PF05080.12 CDJ80444.1 - 0.0063 17.1 0.2 0.01 16.4 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF681) DUF681 PF05080.12 CDJ80445.1 - 0.0053 17.4 0.1 0.018 15.7 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF681) HOCHOB PF17943.1 CDJ80447.1 - 0.012 16.3 0.1 0.081 13.6 0.0 2.0 2 0 0 2 2 2 0 Homeobox-cysteine loop-homeobox DUF643 PF04867.12 CDJ80447.1 - 0.058 14.0 1.0 0.36 11.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF643) DUF3624 PF12292.8 CDJ80448.1 - 0.086 13.3 0.1 0.17 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3624) Motile_Sperm PF00635.26 CDJ80448.1 - 0.17 11.7 0.1 0.29 11.0 0.1 1.2 1 0 0 1 1 1 0 MSP (Major sperm protein) domain PEX-1N PF09262.11 CDJ80450.1 - 0.06 13.8 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal MFS_1 PF07690.16 CDJ80451.1 - 3e-42 144.8 6.3 3.9e-42 144.5 6.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ80451.1 - 2e-05 23.6 7.4 3.2e-05 23.0 7.4 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 CDJ80451.1 - 7.4e-05 22.2 1.8 0.00023 20.6 1.3 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 CDJ80451.1 - 0.0015 17.5 3.0 0.076 11.9 0.7 2.3 3 0 0 3 3 3 2 MFS_1 like family MFS_2 PF13347.6 CDJ80451.1 - 0.0048 15.5 7.9 0.045 12.3 0.0 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein zf-C2H2 PF00096.26 CDJ80452.1 - 6.3e-15 54.7 22.1 5.3e-06 26.6 3.2 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ80452.1 - 3e-14 52.7 23.7 7.1e-10 38.9 0.8 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDJ80452.1 - 4e-10 39.6 21.6 0.00016 22.2 2.3 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 CDJ80452.1 - 0.0094 16.3 5.7 0.14 12.6 0.5 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CDJ80452.1 - 0.1 12.6 1.6 0.1 12.6 1.6 3.7 4 1 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CDJ80452.1 - 0.11 12.3 17.6 0.67 9.8 0.2 3.8 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 CDJ80452.1 - 0.21 12.0 9.0 0.47 10.8 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 CDJ80452.1 - 0.43 11.2 8.3 0.96 10.1 1.6 2.8 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 CDJ80452.1 - 1.5 9.0 5.2 3.6 7.7 2.3 2.2 1 1 1 2 2 2 0 Aberrant zinc-finger SOSSC PF15925.5 CDJ80453.1 - 5.6e-05 24.4 3.7 0.12 13.7 0.6 2.1 1 1 1 2 2 2 2 SOSS complex subunit C IHABP4_N PF16174.5 CDJ80454.1 - 2.2e-05 25.1 6.9 2.6e-05 24.9 5.8 1.7 1 1 0 1 1 1 1 Intracellular hyaluronan-binding protein 4 N-terminal FoP_duplication PF13865.6 CDJ80454.1 - 0.013 16.0 2.6 0.013 16.0 2.6 3.3 2 1 1 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 TMF_TATA_bd PF12325.8 CDJ80454.1 - 0.08 13.2 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Sugar_tr PF00083.24 CDJ80455.1 - 6.1e-27 94.6 19.3 9.4e-27 94.0 19.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ80455.1 - 2.9e-24 85.7 38.6 2e-22 79.6 19.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily 60KD_IMP PF02096.20 CDJ80455.1 - 1.4 8.8 0.0 1.4 8.8 0.0 2.8 3 1 0 3 3 3 0 60Kd inner membrane protein TSP_1 PF00090.19 CDJ80456.1 - 4e-05 23.7 12.4 0.0001 22.4 12.4 1.7 1 0 0 1 1 1 1 Thrombospondin type 1 domain Macoilin PF09726.9 CDJ80456.1 - 0.76 8.3 3.7 0.82 8.2 3.7 1.0 1 0 0 1 1 1 0 Macoilin family FSA_C PF10479.9 CDJ80456.1 - 9.3 4.2 20.2 11 4.0 20.2 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Citrate_bind PF16114.5 CDJ80457.1 - 1.7e-87 291.5 0.0 2.8e-87 290.8 0.0 1.4 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 CDJ80457.1 - 1.9e-23 83.1 0.0 1.4e-21 77.0 0.0 3.1 2 1 1 3 3 3 1 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 CDJ80457.1 - 5.9e-18 65.1 0.3 1.4e-17 64.0 0.3 1.7 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 CDJ80457.1 - 8.7e-12 45.6 0.0 2.8e-11 43.9 0.0 2.0 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 CDJ80457.1 - 2.2e-08 33.9 0.0 4.4e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 CDJ80457.1 - 0.0028 17.4 0.1 0.062 13.1 0.0 2.5 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Cyto_heme_lyase PF01265.17 CDJ80458.1 - 2.7e-63 214.3 8.3 2.6e-62 211.0 8.3 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase COX15-CtaA PF02628.15 CDJ80459.1 - 8.5e-102 340.5 6.5 9.9e-102 340.3 6.5 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein SirB PF04247.12 CDJ80459.1 - 0.0016 18.5 0.2 0.0016 18.5 0.2 2.3 2 1 0 2 2 2 1 Invasion gene expression up-regulator, SirB SK_channel PF03530.14 CDJ80459.1 - 0.084 12.9 0.2 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 Calcium-activated SK potassium channel Collagen PF01391.18 CDJ80460.1 - 1.1e-17 63.5 120.1 1.6e-08 34.2 40.5 4.4 2 1 1 3 3 3 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ80460.1 - 1.2e-12 47.7 0.3 1.8e-12 47.1 0.3 1.3 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain DUF1679 PF07914.11 CDJ80461.1 - 8.1e-67 225.9 0.6 2.7e-51 174.7 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1679) EcKinase PF02958.20 CDJ80461.1 - 3.4e-07 29.9 5.0 3.3e-06 26.6 0.6 2.8 1 1 2 3 3 3 2 Ecdysteroid kinase APH PF01636.23 CDJ80461.1 - 2.3e-05 24.5 0.0 5.7e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family ING PF12998.7 CDJ80461.1 - 0.13 12.9 0.7 2.2 8.9 0.3 2.7 2 1 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding CBM_14 PF01607.24 CDJ80462.1 - 3.6e-82 270.4 111.4 5e-11 42.6 7.6 9.1 9 0 0 9 9 9 9 Chitin binding Peritrophin-A domain 3HCDH PF00725.22 CDJ80463.1 - 2.3e-14 53.8 0.0 4.6e-14 52.8 0.0 1.6 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Dioxygenase_C PF00775.21 CDJ80463.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Dioxygenase NDK PF00334.19 CDJ80464.1 - 6.3e-42 142.8 0.0 7.8e-42 142.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Pkinase_Tyr PF07714.17 CDJ80465.1 - 1.2e-59 201.7 0.0 1.1e-57 195.3 0.0 2.1 1 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CDJ80465.1 - 6.8e-25 87.9 0.0 1.3e-23 83.7 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain Haspin_kinase PF12330.8 CDJ80465.1 - 0.033 13.1 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain LepB_GAP_C PF18227.1 CDJ80465.1 - 0.04 14.4 0.0 0.097 13.2 0.0 1.6 1 0 0 1 1 1 0 LepB GAP domain C-terminal subdomain CPSase_L_D2 PF02786.17 CDJ80467.1 - 8.6e-82 273.7 0.1 1.3e-81 273.1 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.28 CDJ80467.1 - 1.3e-47 162.1 0.0 2.9e-47 160.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 CDJ80467.1 - 7.2e-45 151.9 0.0 1.3e-44 151.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.19 CDJ80467.1 - 2.7e-37 127.8 0.1 7.2e-37 126.5 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Peptidase_C26 PF07722.13 CDJ80467.1 - 2e-07 31.0 0.1 3.1e-05 23.8 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 Dala_Dala_lig_C PF07478.13 CDJ80467.1 - 5.3e-07 29.4 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 CDJ80467.1 - 5.1e-05 23.0 0.0 0.00015 21.5 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.22 CDJ80467.1 - 6.6e-05 22.5 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain DJ-1_PfpI PF01965.24 CDJ80467.1 - 0.00012 21.9 0.0 0.21 11.3 0.0 3.3 3 0 0 3 3 3 1 DJ-1/PfpI family ATP-grasp_3 PF02655.14 CDJ80467.1 - 0.037 14.1 0.0 0.084 12.9 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain zf-RING_2 PF13639.6 CDJ80468.1 - 8.9e-05 22.7 38.2 0.0023 18.2 6.0 4.2 4 0 0 4 4 4 3 Ring finger domain zf-C3HC4 PF00097.25 CDJ80468.1 - 0.00017 21.4 1.4 0.00017 21.4 1.4 4.1 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ80468.1 - 0.0011 18.7 5.1 0.0011 18.7 5.1 4.6 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ80468.1 - 0.0022 17.9 6.2 0.0022 17.9 6.2 4.3 4 0 0 4 4 4 2 zinc-RING finger domain Prok-RING_4 PF14447.6 CDJ80468.1 - 0.019 14.8 2.0 0.019 14.8 2.0 4.6 4 1 0 4 4 4 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CDJ80468.1 - 0.025 14.4 6.3 0.025 14.4 6.3 5.5 3 1 3 6 6 6 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 CDJ80468.1 - 0.029 14.3 1.9 0.029 14.3 1.9 4.0 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ80468.1 - 0.13 12.2 40.5 0.043 13.7 9.6 3.9 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ80468.1 - 6.5 7.0 27.0 0.15 12.3 3.7 4.1 4 0 0 4 4 4 0 zinc finger of C3HC4-type, RING Motile_Sperm PF00635.26 CDJ80469.1 - 4.2e-46 155.3 0.0 5.8e-22 77.6 0.0 2.0 2 0 0 2 2 2 2 MSP (Major sperm protein) domain Sortase PF04203.13 CDJ80469.1 - 1.3e-05 25.0 0.0 0.18 11.6 0.0 2.1 2 0 0 2 2 2 2 Sortase domain PT-HINT PF07591.11 CDJ80469.1 - 0.062 13.5 0.0 14 5.9 0.0 2.2 2 0 0 2 2 2 0 Pretoxin HINT domain Meth_synt_2 PF01717.18 CDJ80469.1 - 0.088 12.1 0.0 12 5.0 0.0 2.2 2 0 0 2 2 2 0 Cobalamin-independent synthase, Catalytic domain SCA7 PF08313.12 CDJ80469.1 - 0.13 12.1 0.0 24 4.9 0.0 2.3 2 0 0 2 2 2 0 SCA7, zinc-binding domain DUF2518 PF10726.9 CDJ80469.1 - 0.13 11.9 0.0 21 4.7 0.0 2.2 2 0 0 2 2 2 0 Protein of function (DUF2518) CtsR_C PF17727.1 CDJ80469.1 - 0.17 12.0 0.0 30 4.8 0.0 2.3 2 0 0 2 2 2 0 CtsR C-terminal dimerization domain Motile_Sperm PF00635.26 CDJ80470.1 - 2.3e-22 78.9 0.0 2.5e-22 78.8 0.0 1.0 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Sortase PF04203.13 CDJ80470.1 - 0.028 14.2 0.0 0.038 13.8 0.0 1.1 1 0 0 1 1 1 0 Sortase domain Ground-like PF04155.18 CDJ80471.1 - 3.1e-12 46.9 0.0 5.1e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Ground-like domain Hamartin PF04388.12 CDJ80471.1 - 0.67 8.6 5.2 0.86 8.2 5.2 1.0 1 0 0 1 1 1 0 Hamartin protein PRCC PF10253.9 CDJ80471.1 - 1.3 9.8 6.0 2 9.2 6.0 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting EIF_2_alpha PF07541.12 CDJ80472.1 - 1.2e-36 125.3 0.1 3e-36 124.0 0.1 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 CDJ80472.1 - 2.8e-12 46.8 1.1 2.8e-12 46.8 1.1 1.6 2 0 0 2 2 2 1 S1 RNA binding domain Band_7 PF01145.25 CDJ80473.1 - 1.2e-23 84.1 1.0 1.7e-23 83.5 0.4 1.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family Ribosomal_L27A PF00828.19 CDJ80474.1 - 1.5e-23 83.9 0.0 2e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_60s PF00428.19 CDJ80475.1 - 1.9e-26 92.5 5.8 2.4e-26 92.1 5.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Arf PF00025.21 CDJ80476.1 - 4.6e-32 110.9 0.0 7.2e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CDJ80476.1 - 4.7e-10 39.2 1.7 4.2e-06 26.2 0.0 2.6 2 1 1 3 3 3 2 G-protein alpha subunit Roc PF08477.13 CDJ80476.1 - 4.5e-09 36.6 0.0 8.1e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDJ80476.1 - 2.7e-06 27.1 0.0 3.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CDJ80476.1 - 6.4e-05 22.5 0.4 0.00016 21.2 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CDJ80476.1 - 8.4e-05 22.6 0.0 0.0002 21.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDJ80476.1 - 0.0003 20.2 0.0 0.00059 19.3 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MAGI_u5 PF16666.5 CDJ80476.1 - 0.009 16.2 2.7 0.015 15.4 2.7 1.4 1 0 0 1 1 1 1 Unstructured region on MAGI ABC_tran PF00005.27 CDJ80476.1 - 0.0098 16.4 0.3 0.04 14.4 0.0 2.0 2 0 0 2 2 2 1 ABC transporter GTP_EFTU PF00009.27 CDJ80476.1 - 0.13 11.8 0.6 0.37 10.3 0.0 1.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 CDJ80476.1 - 0.14 11.9 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain LA-virus_coat PF09220.10 CDJ80477.1 - 0.092 11.4 0.1 0.32 9.6 0.1 1.7 2 0 0 2 2 2 0 L-A virus, major coat protein FMO-like PF00743.19 CDJ80478.1 - 1.6e-167 558.1 0.0 2e-167 557.8 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CDJ80478.1 - 1.1e-18 67.5 0.1 5.1e-15 55.5 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CDJ80478.1 - 9.8e-09 34.9 0.0 1.1e-07 31.5 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CDJ80478.1 - 3.5e-08 33.0 1.3 2.9e-06 26.7 0.1 3.2 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CDJ80478.1 - 0.002 18.3 0.0 0.0046 17.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CDJ80478.1 - 0.0069 16.4 0.8 0.31 11.0 0.1 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 CDJ80478.1 - 0.023 15.2 0.6 2.7 8.6 0.1 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDJ80478.1 - 0.03 13.6 0.0 0.54 9.4 0.0 2.3 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 CDJ80478.1 - 0.035 13.7 0.1 4.5 6.7 0.0 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase Peptidase_M17_N PF02789.17 CDJ80478.1 - 0.036 13.9 0.1 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain HI0933_like PF03486.14 CDJ80478.1 - 0.18 10.4 0.1 0.41 9.3 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein Peptidase_M14 PF00246.24 CDJ80481.1 - 1.6e-70 238.2 0.0 1.9e-70 238.0 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase HSP20 PF00011.21 CDJ80482.1 - 3e-20 72.3 0.1 3.7e-20 72.0 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ80482.1 - 7.2e-06 25.5 0.0 1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 CDJ80482.1 - 0.0065 17.5 0.3 0.091 13.8 0.3 2.1 1 1 1 2 2 2 2 CS domain CIA30 PF08547.12 CDJ80482.1 - 0.0068 16.4 0.1 0.0076 16.3 0.1 1.3 1 1 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Glyco_hydro_65C PF03633.15 CDJ80482.1 - 0.061 13.2 0.1 15 5.5 0.0 2.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 65, C-terminal domain DUF5640 PF18692.1 CDJ80482.1 - 0.11 12.5 0.0 0.29 11.2 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5640) ComJ PF11033.8 CDJ80482.1 - 0.12 12.1 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Competence protein J (ComJ) HSP20 PF00011.21 CDJ80483.1 - 6.1e-24 84.1 0.9 8.1e-24 83.7 0.9 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ80483.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 HSP20-like domain found in ArsA HSP20 PF00011.21 CDJ80484.1 - 1.3e-21 76.7 0.1 1.7e-21 76.2 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ80484.1 - 0.0096 15.5 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF5640 PF18692.1 CDJ80484.1 - 0.17 11.9 0.0 0.34 11.0 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5640) HSP20 PF00011.21 CDJ80485.1 - 4.9e-23 81.2 0.2 6.2e-23 80.9 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ80485.1 - 0.0011 18.5 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF2807 PF10988.8 CDJ80485.1 - 0.23 11.2 0.7 0.58 9.9 0.4 1.7 1 1 1 2 2 2 0 Putative auto-transporter adhesin, head GIN domain HSP20 PF00011.21 CDJ80486.1 - 2.3e-21 75.8 0.1 3.5e-21 75.3 0.1 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ80486.1 - 0.00098 18.6 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF5640 PF18692.1 CDJ80486.1 - 0.013 15.5 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5640) HSP20 PF00011.21 CDJ80487.1 - 9.9e-22 77.0 0.1 1.3e-21 76.7 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ80487.1 - 6.3e-05 22.4 0.0 0.00014 21.3 0.0 1.6 2 0 0 2 2 2 1 HSP20-like domain found in ArsA DUF5640 PF18692.1 CDJ80487.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5640) HSP20 PF00011.21 CDJ80488.1 - 2.1e-21 76.0 0.2 2.7e-21 75.6 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ80488.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 0 HSP20-like domain found in ArsA HSP20 PF00011.21 CDJ80489.1 - 1.5e-21 76.5 0.1 1.9e-21 76.1 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ80489.1 - 0.00021 20.8 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF5640 PF18692.1 CDJ80489.1 - 0.074 13.1 0.0 0.17 12.0 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5640) NHL PF01436.21 CDJ80494.1 - 4.7e-59 193.6 23.8 2.2e-10 40.0 0.3 6.8 6 0 0 6 6 6 6 NHL repeat SGL PF08450.12 CDJ80494.1 - 1.2e-07 31.6 0.3 1.5 8.4 0.0 5.0 2 1 3 5 5 5 2 SMP-30/Gluconolactonase/LRE-like region DUF5128 PF17170.4 CDJ80494.1 - 1.7e-07 30.7 2.5 0.0013 18.0 0.3 3.4 2 1 1 3 3 3 2 6-bladed beta-propeller zf-B_box PF00643.24 CDJ80494.1 - 1.9e-06 27.9 1.6 1.9e-06 27.9 1.6 3.7 3 1 0 3 3 2 2 B-box zinc finger Filamin PF00630.19 CDJ80494.1 - 8.9e-05 23.3 0.0 0.00023 21.9 0.0 1.8 1 0 0 1 1 1 1 Filamin/ABP280 repeat DUF4934 PF16288.5 CDJ80494.1 - 0.025 14.5 0.3 0.52 10.3 0.0 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF4934) DUF4968 PF16338.5 CDJ80494.1 - 0.043 14.1 0.0 0.72 10.2 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4968) Phytase-like PF13449.6 CDJ80494.1 - 0.047 13.6 0.2 43 3.9 0.0 3.9 2 1 1 3 3 3 0 Esterase-like activity of phytase MAS20 PF02064.15 CDJ80494.1 - 0.15 12.2 0.9 0.26 11.4 0.9 1.3 1 0 0 1 1 1 0 MAS20 protein import receptor Muted PF14942.6 CDJ80494.1 - 0.17 12.2 3.4 0.29 11.5 3.4 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Spc7 PF08317.11 CDJ80494.1 - 1.1 8.0 8.5 1.6 7.5 8.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Allexi_40kDa PF05549.11 CDJ80494.1 - 1.3 8.5 4.2 1 8.8 2.7 1.5 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF1664 PF07889.12 CDJ80494.1 - 1.5 8.8 5.6 4 7.5 4.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PgaPase_1 PF06162.12 CDJ80495.1 - 2.2e-14 53.6 0.1 3.1e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 Putative pyroglutamyl peptidase PgaPase_1 Peptidase_C15 PF01470.17 CDJ80495.1 - 1.3e-12 48.3 0.0 1.7e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Pyroglutamyl peptidase Pkinase PF00069.25 CDJ80496.1 - 1.7e-96 322.7 0.0 3.5e-75 252.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ80496.1 - 1.2e-41 142.8 0.2 3.6e-36 124.8 0.0 3.6 4 0 0 4 4 4 2 Protein tyrosine kinase Kdo PF06293.14 CDJ80496.1 - 0.0055 16.1 0.2 0.019 14.3 0.2 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CDJ80496.1 - 0.0076 15.3 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 DUF4434 PF14488.6 CDJ80496.1 - 0.0086 16.1 0.0 6.7 6.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4434) Anoct_dimer PF16178.5 CDJ80496.1 - 0.013 15.3 0.2 0.031 14.0 0.2 1.6 1 0 0 1 1 1 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin RIO1 PF01163.22 CDJ80496.1 - 0.021 14.4 0.2 0.04 13.5 0.2 1.3 1 0 0 1 1 1 0 RIO1 family Histone_H2A_C PF16211.5 CDJ80496.1 - 0.031 14.0 0.1 15 5.4 0.0 2.7 2 0 0 2 2 2 0 C-terminus of histone H2A Haspin_kinase PF12330.8 CDJ80496.1 - 0.077 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Type_III_YscX PF09474.10 CDJ80496.1 - 0.081 13.2 0.1 11 6.3 0.0 2.4 2 0 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) HEAT PF02985.22 CDJ80497.1 - 4.7e-12 45.1 13.9 0.024 14.9 0.0 8.0 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 CDJ80497.1 - 2.5e-11 43.8 1.3 0.0018 18.6 0.2 6.4 6 1 1 7 7 7 2 HEAT repeats KAP_NTPase PF07693.14 CDJ80497.1 - 0.044 13.0 0.0 0.087 12.1 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain HEAT_EZ PF13513.6 CDJ80497.1 - 0.051 14.1 6.6 0.48 11.0 0.0 4.5 4 0 0 4 4 4 0 HEAT-like repeat Pkinase PF00069.25 CDJ80499.1 - 1.4e-25 90.2 0.0 1.8e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ80499.1 - 2.1e-08 33.8 0.0 3.1e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ80499.1 - 3.2e-05 23.4 0.0 5.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Exo_endo_phos PF03372.23 CDJ80500.1 - 0.16 11.5 0.0 0.69 9.4 0.0 1.9 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family AAA_12 PF13087.6 CDJ80501.1 - 1.5e-35 122.6 0.0 2.4e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CDJ80501.1 - 2.3e-10 40.6 0.0 2.6e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 CDJ80501.1 - 1.4e-08 34.8 0.0 3.6e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ80501.1 - 1.8e-08 34.3 0.0 9.5e-05 22.2 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CDJ80501.1 - 7e-06 26.4 0.0 5.7e-05 23.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 CDJ80501.1 - 0.0019 18.1 0.2 0.57 10.0 0.1 2.4 2 0 0 2 2 2 2 Helicase DEAD PF00270.29 CDJ80501.1 - 0.003 17.4 0.0 0.86 9.3 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase UvrD_C_2 PF13538.6 CDJ80501.1 - 0.015 15.1 0.0 0.16 11.9 0.0 2.8 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain ResIII PF04851.15 CDJ80501.1 - 0.059 13.4 0.0 0.29 11.1 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Ank_2 PF12796.7 CDJ80502.1 - 2.9e-08 34.2 0.3 5e-08 33.4 0.3 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ80502.1 - 1.2e-05 25.5 0.4 0.00023 21.4 0.3 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ80502.1 - 4.5e-05 23.5 0.2 0.0035 17.7 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 CDJ80502.1 - 0.00012 22.5 0.1 0.0003 21.3 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CDJ80502.1 - 0.00045 20.5 0.2 0.059 13.8 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeat PH PF00169.29 CDJ80503.1 - 5.7e-13 49.3 0.2 5.7e-13 49.3 0.2 2.3 2 1 1 3 3 3 1 PH domain PH_4 PF15404.6 CDJ80503.1 - 0.016 15.0 0.2 0.016 15.0 0.2 3.0 2 1 2 4 4 4 0 Pleckstrin homology domain PH_11 PF15413.6 CDJ80503.1 - 0.04 14.3 0.4 0.04 14.3 0.4 3.0 3 1 0 3 3 3 0 Pleckstrin homology domain PH_8 PF15409.6 CDJ80503.1 - 0.21 11.9 6.0 0.098 13.0 2.3 2.4 3 0 0 3 3 3 0 Pleckstrin homology domain ANF_receptor PF01094.28 CDJ80504.1 - 1.2e-11 44.4 0.0 1.4e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region ANF_receptor PF01094.28 CDJ80505.1 - 8.6e-06 25.1 0.0 8.6e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region ANF_receptor PF01094.28 CDJ80506.1 - 0.0032 16.6 0.0 0.0036 16.4 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region CRAL_TRIO PF00650.20 CDJ80507.1 - 0.004 16.9 0.0 0.0062 16.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain IBN_N PF03810.19 CDJ80508.1 - 1.5e-12 47.2 0.1 3.5e-12 46.1 0.1 1.6 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CDJ80508.1 - 2.7e-12 47.0 1.2 2.7e-12 47.0 1.2 2.1 2 1 0 2 2 2 1 Exportin 1-like protein ASPRs PF17641.2 CDJ80510.1 - 0.0028 17.9 0.1 0.0037 17.5 0.1 1.2 1 0 0 1 1 1 1 Ancylostoma-associated secreted protein related BAR PF03114.18 CDJ80510.1 - 0.1 12.2 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 BAR domain PRO8NT PF08082.11 CDJ80512.1 - 0.034 14.1 0.3 0.039 13.9 0.3 1.0 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain ANF_receptor PF01094.28 CDJ80514.1 - 5.8e-18 65.1 0.4 1.2e-17 64.1 0.4 1.6 1 1 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 CDJ80514.1 - 0.0057 16.4 0.0 0.0092 15.7 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein CMAS PF02353.20 CDJ80515.1 - 0.1 11.9 0.0 0.11 11.7 0.0 1.0 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Pkinase PF00069.25 CDJ80518.1 - 7.2e-26 91.1 0.0 1.1e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ80518.1 - 3.4e-10 39.6 0.0 4.6e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase CLZ PF16526.5 CDJ80519.1 - 1.7e-05 25.1 7.2 1.7e-05 25.1 7.2 2.2 1 1 1 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Csm1_N PF18504.1 CDJ80519.1 - 0.0019 18.5 7.4 0.0019 18.5 7.4 2.4 1 1 2 3 3 3 1 Csm1 N-terminal domain SHE3 PF17078.5 CDJ80519.1 - 0.0099 15.6 13.4 0.013 15.3 13.4 1.1 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 GAS PF13851.6 CDJ80519.1 - 0.012 14.9 13.7 0.017 14.5 13.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding SlyX PF04102.12 CDJ80519.1 - 0.018 15.7 6.1 0.018 15.7 6.1 2.4 1 1 1 2 2 2 0 SlyX bZIP_1 PF00170.21 CDJ80519.1 - 0.024 14.7 4.7 0.024 14.7 4.7 3.1 1 1 1 3 3 3 0 bZIP transcription factor BLOC1_2 PF10046.9 CDJ80519.1 - 0.025 14.9 10.2 0.062 13.6 7.9 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-C4H2 PF10146.9 CDJ80519.1 - 0.027 14.8 9.6 0.03 14.6 9.6 1.0 1 0 0 1 1 1 0 Zinc finger-containing protein CCDC85 PF10226.9 CDJ80519.1 - 0.03 14.0 7.7 0.056 13.1 7.7 1.5 1 1 0 1 1 1 0 CCDC85 family DUF812 PF05667.11 CDJ80519.1 - 0.051 12.5 13.4 0.056 12.3 13.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) LXG PF04740.12 CDJ80519.1 - 0.052 13.3 3.5 0.075 12.7 3.5 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily MbeD_MobD PF04899.12 CDJ80519.1 - 0.064 13.4 2.8 3.4 7.9 2.8 2.3 1 1 0 1 1 1 0 MbeD/MobD like PKcGMP_CC PF16808.5 CDJ80519.1 - 0.068 13.0 17.2 1.1 9.2 1.3 4.1 4 1 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase GIT1_C PF12205.8 CDJ80519.1 - 0.069 13.3 4.9 0.13 12.4 4.7 1.5 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF4407 PF14362.6 CDJ80519.1 - 0.076 12.4 3.9 0.089 12.1 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4618 PF15397.6 CDJ80519.1 - 0.085 12.3 13.9 0.18 11.2 4.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) DUF2400 PF09674.10 CDJ80519.1 - 0.096 12.7 0.3 0.11 12.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Wbp11 PF09429.10 CDJ80519.1 - 0.096 13.1 16.1 0.14 12.5 7.2 2.3 1 1 1 2 2 2 0 WW domain binding protein 11 DUF4107 PF13389.6 CDJ80519.1 - 0.1 12.7 2.1 0.12 12.5 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) DUF148 PF02520.17 CDJ80519.1 - 0.11 12.6 7.6 0.3 11.2 7.7 1.7 1 1 0 1 1 1 0 Domain of unknown function DUF148 HBM PF16591.5 CDJ80519.1 - 0.12 11.8 5.1 0.19 11.1 5.1 1.3 1 1 0 1 1 1 0 Helical bimodular sensor domain Exonuc_VII_L PF02601.15 CDJ80519.1 - 0.12 11.9 4.3 0.13 11.8 4.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_HK97_TLTM PF06120.11 CDJ80519.1 - 0.12 11.5 5.4 0.14 11.3 5.4 1.1 1 0 0 1 1 1 0 Tail length tape measure protein DUF4164 PF13747.6 CDJ80519.1 - 0.13 12.6 13.1 0.61 10.4 12.9 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) Acetyltransf_11 PF13720.6 CDJ80519.1 - 0.13 12.7 1.5 0.27 11.7 0.8 1.8 1 1 1 2 2 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 PCRF PF03462.18 CDJ80519.1 - 0.15 12.0 9.9 0.18 11.6 9.9 1.1 1 0 0 1 1 1 0 PCRF domain DUF948 PF06103.11 CDJ80519.1 - 0.16 12.3 3.2 0.34 11.2 0.8 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Wtap PF17098.5 CDJ80519.1 - 0.16 11.9 15.3 0.3 11.0 9.3 2.6 1 1 2 3 3 3 0 WTAP/Mum2p family Het-C PF07217.11 CDJ80519.1 - 0.16 10.4 1.2 0.18 10.3 1.2 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Phage_GPO PF05929.11 CDJ80519.1 - 0.17 11.5 4.7 0.21 11.2 4.7 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase TMF_DNA_bd PF12329.8 CDJ80519.1 - 0.22 11.6 25.1 0.1 12.6 10.8 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 CDJ80519.1 - 0.22 10.4 17.6 0.48 9.2 17.6 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Fzo_mitofusin PF04799.13 CDJ80519.1 - 0.34 10.4 9.8 11 5.5 9.3 2.1 1 1 0 1 1 1 0 fzo-like conserved region DASH_Dam1 PF08653.10 CDJ80519.1 - 0.4 10.5 1.4 2 8.3 0.2 2.5 2 1 1 3 3 2 0 DASH complex subunit Dam1 TMF_TATA_bd PF12325.8 CDJ80519.1 - 0.42 10.8 18.2 2.7 8.3 9.5 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF16 PF01519.16 CDJ80519.1 - 0.47 11.0 11.5 0.81 10.2 6.1 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 BRE1 PF08647.11 CDJ80519.1 - 0.5 10.5 16.2 1.6 8.9 16.2 1.8 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase JIP_LZII PF16471.5 CDJ80519.1 - 0.52 10.5 16.0 0.18 12.0 8.3 2.6 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II SWI-SNF_Ssr4 PF08549.10 CDJ80519.1 - 0.52 8.9 9.0 0.59 8.7 9.0 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) MetOD2 PF18548.1 CDJ80519.1 - 0.54 10.4 10.2 0.49 10.5 7.1 2.3 1 1 1 2 2 2 0 Metanogen output domain 2 Atg14 PF10186.9 CDJ80519.1 - 0.55 9.3 12.3 0.73 8.9 12.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TSC22 PF01166.18 CDJ80519.1 - 0.55 10.6 13.6 1.9 8.9 2.5 3.2 1 1 2 3 3 3 0 TSC-22/dip/bun family LCIB_C_CA PF18599.1 CDJ80519.1 - 0.6 9.4 2.6 0.72 9.1 2.6 1.2 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases FAM76 PF16046.5 CDJ80519.1 - 0.63 9.3 12.7 0.85 8.9 12.7 1.3 1 1 0 1 1 1 0 FAM76 protein Shugoshin_N PF07558.11 CDJ80519.1 - 0.65 9.9 14.7 5.7 6.9 1.7 3.5 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region ADIP PF11559.8 CDJ80519.1 - 0.66 10.0 15.7 2.3 8.3 5.7 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Prominin PF05478.11 CDJ80519.1 - 0.71 7.8 4.2 0.85 7.5 4.2 1.1 1 0 0 1 1 1 0 Prominin Cnn_1N PF07989.11 CDJ80519.1 - 0.74 10.0 17.9 4.7 7.4 3.4 3.2 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF3450 PF11932.8 CDJ80519.1 - 0.79 9.0 10.6 2.6 7.3 10.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.19 CDJ80519.1 - 0.81 7.5 6.3 0.88 7.4 6.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Swi5 PF07061.11 CDJ80519.1 - 0.87 9.7 12.9 1.1 9.4 3.5 2.3 2 0 0 2 2 2 0 Swi5 DUF4250 PF14056.6 CDJ80519.1 - 0.94 9.5 4.8 6.4 6.8 0.5 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4250) Spectrin PF00435.21 CDJ80519.1 - 1.1 9.8 10.9 2 9.0 10.9 1.5 1 1 0 1 1 1 0 Spectrin repeat ATG16 PF08614.11 CDJ80519.1 - 1.1 9.4 17.1 1.3 9.2 16.2 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 CDJ80519.1 - 1.2 9.2 7.2 0.71 9.9 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 CDJ80519.1 - 1.4 8.9 10.7 1.4 8.9 3.6 2.0 1 1 1 2 2 2 0 Laminin Domain II DUF4145 PF13643.6 CDJ80519.1 - 1.4 9.1 4.9 7 6.9 0.5 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4145) HAUS6_N PF14661.6 CDJ80519.1 - 1.6 8.3 8.8 2.6 7.6 8.8 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Jnk-SapK_ap_N PF09744.9 CDJ80519.1 - 1.7 8.8 17.3 4.2 7.6 17.3 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 HAUS-augmin3 PF14932.6 CDJ80519.1 - 1.9 8.0 14.4 2.8 7.5 1.5 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 AAA_13 PF13166.6 CDJ80519.1 - 2.3 6.7 13.0 3.5 6.1 10.2 1.6 1 1 1 2 2 2 0 AAA domain FapA PF03961.13 CDJ80519.1 - 2.6 6.6 12.0 3.1 6.3 12.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A HTH_Tnp_1 PF01527.20 CDJ80519.1 - 2.6 8.4 9.0 2.2 8.7 1.0 2.9 1 1 2 3 3 3 0 Transposase DMPK_coil PF08826.10 CDJ80519.1 - 2.7 8.2 19.7 0.28 11.3 2.8 3.2 1 1 2 3 3 3 0 DMPK coiled coil domain like DUF848 PF05852.11 CDJ80519.1 - 2.8 8.0 11.1 8.4 6.5 11.1 1.7 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DivIC PF04977.15 CDJ80519.1 - 3.1 7.6 17.6 8.8 6.2 2.4 3.1 1 1 2 3 3 3 0 Septum formation initiator bZIP_2 PF07716.15 CDJ80519.1 - 3.2 7.9 19.4 0.64 10.1 2.5 3.4 1 1 1 3 3 3 0 Basic region leucine zipper HemX PF04375.14 CDJ80519.1 - 3.6 6.8 8.9 9.8 5.4 8.9 1.7 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase KIP1 PF07765.12 CDJ80519.1 - 3.7 7.7 9.6 2.1 8.5 4.4 2.1 1 1 1 2 2 2 0 KIP1-like protein DUF1192 PF06698.11 CDJ80519.1 - 3.8 7.7 11.8 0.8 9.8 0.6 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1192) XhlA PF10779.9 CDJ80519.1 - 4 7.7 15.0 5.7 7.2 6.9 2.3 2 0 0 2 2 2 0 Haemolysin XhlA DUF5398 PF17376.2 CDJ80519.1 - 4 8.1 9.6 1.6 9.4 5.9 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5398) OmpH PF03938.14 CDJ80519.1 - 4.1 7.7 13.8 8.5 6.7 13.4 1.6 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Exonuc_VII_S PF02609.16 CDJ80519.1 - 5 7.3 15.2 0.37 10.9 7.9 2.6 2 1 0 2 2 2 0 Exonuclease VII small subunit UPF0242 PF06785.11 CDJ80519.1 - 5.2 7.1 17.1 10 6.2 17.1 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Med21 PF11221.8 CDJ80519.1 - 5.3 7.3 14.3 14 6.0 14.2 1.7 1 1 0 1 1 1 0 Subunit 21 of Mediator complex APG6_N PF17675.1 CDJ80519.1 - 5.6 7.5 21.7 48 4.5 21.7 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF724 PF05266.14 CDJ80519.1 - 6.3 6.6 16.1 0.91 9.3 6.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) UPF0449 PF15136.6 CDJ80519.1 - 9 6.8 12.2 6.5e+02 0.9 12.2 2.4 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 COG2 PF06148.11 CDJ80519.1 - 9.6 6.3 11.3 2.1 8.4 3.9 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Ax_dynein_light PF10211.9 CDJ80519.1 - 9.7 6.1 17.7 2.3 8.1 7.5 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain WBP-1 PF11669.8 CDJ80520.1 - 0.0047 17.5 0.0 0.99 10.1 0.0 2.9 2 1 1 3 3 3 1 WW domain-binding protein 1 Xin PF08043.12 CDJ80520.1 - 0.0057 16.2 0.1 4.2 7.1 0.0 2.3 2 0 0 2 2 2 2 Xin repeat ApoC-I PF04691.12 CDJ80520.1 - 0.012 15.5 0.2 1.7 8.6 0.1 2.2 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) DNA_pol3_theta PF06440.11 CDJ80520.1 - 0.037 13.7 0.0 10 5.9 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase III, theta subunit DUF447 PF04289.12 CDJ80520.1 - 0.043 13.6 0.2 0.87 9.3 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF447) DUF3349 PF11829.8 CDJ80520.1 - 0.065 14.0 0.1 0.18 12.6 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) DUF3232 PF11554.8 CDJ80520.1 - 0.087 13.2 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) PRA-PH PF01503.17 CDJ80520.1 - 0.17 12.3 0.6 5.9 7.4 0.5 2.3 1 1 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase PBC PF03792.13 CDJ80521.1 - 0.048 13.4 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 PBC domain Homeodomain PF00046.29 CDJ80525.1 - 1.8e-22 78.9 5.8 3e-22 78.2 5.8 1.4 1 0 0 1 1 1 1 Homeodomain Filo_glycop PF01611.16 CDJ80525.1 - 0.011 14.7 0.5 0.013 14.4 0.5 1.1 1 0 0 1 1 1 0 Filovirus glycoprotein Terminase_5 PF06056.12 CDJ80525.1 - 0.044 13.7 0.3 0.088 12.7 0.3 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Homeobox_KN PF05920.11 CDJ80525.1 - 0.085 12.8 1.2 0.085 12.8 1.2 3.0 3 1 0 3 3 3 0 Homeobox KN domain RVT_1 PF00078.27 CDJ80526.1 - 8.8e-39 133.3 0.0 1.5e-38 132.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_1 PF00001.21 CDJ80527.1 - 7.6e-07 28.7 24.1 8.5e-07 28.6 22.2 2.0 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) FGGY_N PF00370.21 CDJ80528.1 - 6.3e-74 248.6 0.0 8.9e-74 248.1 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CDJ80528.1 - 5.6e-46 156.8 0.4 1.3e-45 155.6 0.1 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain TraI_2 PF07514.11 CDJ80528.1 - 0.16 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Putative helicase FA_desaturase PF00487.24 CDJ80529.1 - 7.9e-26 91.4 6.9 7.9e-26 91.4 6.9 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 CDJ80529.1 - 1.2e-16 59.9 0.1 2.5e-16 58.9 0.1 1.6 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Neur_chan_LBD PF02931.23 CDJ80530.1 - 1.3e-38 132.6 1.6 1.5e-36 125.9 1.6 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ80530.1 - 4.3e-09 36.8 2.1 7.7e-09 36.0 2.1 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Vps55 PF04133.14 CDJ80530.1 - 0.044 13.8 2.1 0.13 12.2 2.1 1.8 1 0 0 1 1 1 0 Vacuolar protein sorting 55 DUF5391 PF17369.2 CDJ80530.1 - 0.092 12.8 3.6 0.2 11.7 3.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5391) DUF2678 PF10856.8 CDJ80530.1 - 0.23 11.4 2.1 0.3 11.0 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2678) HTH_48 PF17906.1 CDJ80531.1 - 8.1e-18 64.3 1.5 1.7e-17 63.3 1.5 1.6 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_Tnp_Tc3_2 PF01498.18 CDJ80531.1 - 3.1e-07 30.5 1.8 6.5e-07 29.5 1.8 1.5 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 CDJ80531.1 - 8.7e-06 25.4 0.1 0.0086 15.9 0.0 2.5 2 0 0 2 2 2 2 Homeodomain-like domain HTH_Tnp_IS630 PF01710.16 CDJ80531.1 - 1e-05 25.6 0.1 1.8e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Transposase HTH_38 PF13936.6 CDJ80531.1 - 1.1e-05 25.0 0.2 3.2e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.6 CDJ80531.1 - 2.7e-05 24.7 1.5 3.1e-05 24.5 0.0 1.9 3 0 0 3 3 1 1 Homeodomain-like domain HTH_28 PF13518.6 CDJ80531.1 - 0.00011 22.3 0.0 0.51 10.5 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_50 PF18024.1 CDJ80531.1 - 0.00041 19.9 0.0 0.00081 19.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Transposase_1 PF01359.18 CDJ80531.1 - 0.001 18.8 0.2 0.0055 16.5 0.0 2.1 2 0 0 2 2 2 1 Transposase (partial DDE domain) HTH_29 PF13551.6 CDJ80531.1 - 0.0064 16.5 0.1 0.29 11.2 0.0 2.4 1 1 1 2 2 2 1 Winged helix-turn helix HTH_11 PF08279.12 CDJ80531.1 - 0.013 15.4 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 HTH domain HTH_Tnp_ISL3 PF13542.6 CDJ80531.1 - 0.019 14.4 0.2 1.8 8.1 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.6 CDJ80531.1 - 0.025 14.1 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_40 PF14493.6 CDJ80531.1 - 0.026 15.0 0.1 0.046 14.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_10 PF04967.12 CDJ80531.1 - 0.035 13.9 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain HTH_5 PF01022.20 CDJ80531.1 - 0.058 13.3 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Terminase_5 PF06056.12 CDJ80531.1 - 0.062 13.2 0.1 4.2 7.3 0.1 2.5 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) GerE PF00196.19 CDJ80531.1 - 0.11 12.1 0.2 0.25 10.9 0.2 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Transket_pyr PF02779.24 CDJ80532.1 - 2.4e-47 160.9 0.0 3.3e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CDJ80532.1 - 1e-32 112.6 0.0 2.1e-32 111.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Cluap1 PF10234.9 CDJ80533.1 - 5.8e-90 301.3 11.9 5.8e-90 301.3 11.9 1.4 1 1 0 1 1 1 1 Clusterin-associated protein-1 DUF3450 PF11932.8 CDJ80533.1 - 0.0041 16.4 12.3 0.0041 16.4 12.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) TSKS PF15358.6 CDJ80533.1 - 0.029 12.7 3.7 0.042 12.2 3.7 1.2 1 0 0 1 1 1 0 Testis-specific serine kinase substrate Sulphotransf PF09037.10 CDJ80533.1 - 0.076 12.5 2.0 0.12 11.9 2.0 1.3 1 0 0 1 1 1 0 Stf0 sulphotransferase ApoB100_C PF12491.8 CDJ80533.1 - 0.22 11.5 4.4 0.57 10.2 3.0 2.2 2 0 0 2 2 2 0 Apolipoprotein B100 C terminal Tup_N PF08581.10 CDJ80533.1 - 0.26 11.6 17.8 0.25 11.7 5.2 3.5 4 0 0 4 4 4 0 Tup N-terminal Macoilin PF09726.9 CDJ80533.1 - 0.33 9.5 11.2 0.42 9.1 11.2 1.3 1 0 0 1 1 1 0 Macoilin family V_ATPase_I PF01496.19 CDJ80533.1 - 0.5 8.2 5.5 0.65 7.8 5.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fez1 PF06818.15 CDJ80533.1 - 1.2 9.6 16.5 0.51 10.8 13.7 1.7 1 1 1 2 2 2 0 Fez1 Laminin_II PF06009.12 CDJ80533.1 - 4.7 7.2 13.3 2.5 8.1 0.9 3.1 1 1 2 3 3 3 0 Laminin Domain II TMPIT PF07851.13 CDJ80533.1 - 6.2 6.0 10.9 0.24 10.6 3.0 2.1 1 1 1 2 2 2 0 TMPIT-like protein FTA4 PF13093.6 CDJ80533.1 - 8.5 6.2 15.7 93 2.8 15.7 2.2 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Alk_phosphatase PF00245.20 CDJ80534.1 - 5.8e-97 325.3 0.0 7.2e-97 325.0 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Motile_Sperm PF00635.26 CDJ80534.1 - 6.4e-15 54.9 0.5 1.2e-14 54.1 0.5 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Metalloenzyme PF01676.18 CDJ80534.1 - 0.00012 21.5 0.1 0.0017 17.8 0.0 2.1 2 0 0 2 2 2 1 Metalloenzyme superfamily Sulfatase PF00884.23 CDJ80534.1 - 0.026 13.9 0.0 4.4 6.6 0.0 2.9 3 0 0 3 3 3 0 Sulfatase InPase PF18823.1 CDJ80534.1 - 0.087 12.5 0.9 1.1 8.9 0.1 2.3 2 0 0 2 2 2 0 Inorganic Pyrophosphatase Nup35_RRM PF05172.13 CDJ80534.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Proton_antipo_C PF01010.19 CDJ80534.1 - 0.12 12.0 0.2 0.26 10.9 0.2 1.5 1 0 0 1 1 1 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus Alk_phosphatase PF00245.20 CDJ80535.1 - 3.8e-79 266.6 0.0 4.9e-79 266.2 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 CDJ80535.1 - 0.002 17.6 0.0 0.0038 16.6 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Y_phosphatase PF00102.27 CDJ80536.1 - 1.6e-67 227.5 0.0 1.9e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ80536.1 - 6.8e-05 22.7 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDJ80536.1 - 0.00015 21.8 0.0 0.00022 21.3 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CDJ80536.1 - 0.017 15.2 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate WD40 PF00400.32 CDJ80537.1 - 5.3e-16 58.7 0.9 0.00015 22.5 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ80537.1 - 1.5e-06 28.4 0.0 7.4e-05 23.0 0.0 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_2 PF09068.11 CDJ80538.1 - 1.3e-33 115.7 1.8 2.9e-33 114.6 1.8 1.6 1 0 0 1 1 1 1 EF hand EF-hand_3 PF09069.11 CDJ80538.1 - 1.2e-25 89.7 0.1 4.6e-25 87.9 0.1 2.1 2 0 0 2 2 2 1 EF-hand ZZ PF00569.17 CDJ80538.1 - 1.8e-11 43.6 9.1 3.8e-11 42.6 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 CDJ80538.1 - 0.00073 19.8 6.7 0.0015 18.8 6.7 1.5 1 0 0 1 1 1 1 C1 domain HOOK PF05622.12 CDJ80538.1 - 0.02 13.0 0.4 0.028 12.6 0.4 1.1 1 0 0 1 1 1 0 HOOK protein DUF4472 PF14739.6 CDJ80538.1 - 2.4 8.9 5.9 0.66 10.7 2.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) DUF5082 PF16888.5 CDJ80538.1 - 3.1 8.1 6.5 10 6.4 0.4 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) FAM76 PF16046.5 CDJ80538.1 - 3.6 6.9 18.5 3.3 7.0 5.0 2.4 1 1 1 2 2 2 0 FAM76 protein Srg PF02118.21 CDJ80539.1 - 4.2e-14 52.9 24.8 2.8e-08 33.8 12.2 2.0 1 1 1 2 2 2 2 Srg family chemoreceptor 7TM_GPCR_Srv PF10323.9 CDJ80539.1 - 2e-10 40.5 24.2 1.7e-05 24.4 13.1 2.1 1 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv PufQ PF05398.11 CDJ80539.1 - 0.47 10.6 3.3 1.9 8.7 0.0 3.0 3 0 0 3 3 3 0 PufQ cytochrome subunit DUF2569 PF10754.9 CDJ80539.1 - 0.95 9.9 16.6 3.9 7.9 2.6 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2569) SUR7 PF06687.12 CDJ80539.1 - 1.2 8.7 16.0 0.53 9.9 5.9 2.3 1 1 0 2 2 2 0 SUR7/PalI family Phtf-FEM1B_bdg PF12129.8 CDJ80539.1 - 5.1 6.9 7.9 1.7 8.5 2.2 2.4 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor Srg PF02118.21 CDJ80540.1 - 5e-11 42.8 19.0 5.8e-11 42.6 19.0 1.1 1 0 0 1 1 1 1 Srg family chemoreceptor 7TM_GPCR_Srv PF10323.9 CDJ80540.1 - 2.4e-08 33.7 13.3 2.8e-08 33.5 13.3 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv DUF4293 PF14126.6 CDJ80540.1 - 0.13 12.5 14.9 0.037 14.3 10.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) Srg PF02118.21 CDJ80541.1 - 4.7e-17 62.6 13.6 5.9e-17 62.2 13.6 1.1 1 0 0 1 1 1 1 Srg family chemoreceptor 7TM_GPCR_Srv PF10323.9 CDJ80541.1 - 7.8e-13 48.4 9.5 8.9e-13 48.2 9.5 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 CDJ80541.1 - 2.2e-06 27.5 7.8 2.7e-06 27.2 7.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Sru PF10322.9 CDJ80541.1 - 0.0043 16.4 6.9 0.068 12.5 6.9 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sru UPF0242 PF06785.11 CDJ80541.1 - 0.89 9.6 2.8 0.5 10.4 0.8 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DOMON PF03351.17 CDJ80542.1 - 1.4e-06 28.5 0.1 6.8e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 DOMON domain zf-C4 PF00105.18 CDJ80543.1 - 3.8e-27 94.5 15.1 3.8e-27 94.5 15.1 1.7 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ80543.1 - 6.1e-09 35.8 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-RRPl_C4 PF17026.5 CDJ80543.1 - 2.4 8.3 10.6 5.6 7.1 8.8 2.3 2 1 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type 7TM_GPCR_Srt PF10321.9 CDJ80544.1 - 1.3e-40 139.3 8.9 1.4e-40 139.2 8.9 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt DUF4735 PF15882.5 CDJ80544.1 - 0.039 13.4 0.4 0.049 13.1 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) CECR6_TMEM121 PF14997.6 CDJ80544.1 - 2.2 8.1 7.7 0.25 11.1 2.5 1.9 1 1 1 2 2 2 0 CECR6/TMEM121 family Ndc1_Nup PF09531.10 CDJ80544.1 - 4.6 5.8 8.5 4.6 5.8 6.5 1.7 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup 7TM_GPCR_Srt PF10321.9 CDJ80545.1 - 2.4e-31 108.9 16.4 2.7e-31 108.7 16.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt 7TM_GPCR_Srx PF10328.9 CDJ80545.1 - 0.00011 21.9 11.8 0.00014 21.6 11.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Fucokinase PF07959.12 CDJ80546.1 - 5.7e-07 28.8 0.0 7.2e-05 21.9 0.0 2.5 2 1 0 2 2 2 2 L-fucokinase GHMP_kinases_N PF00288.26 CDJ80546.1 - 1e-06 28.9 0.2 2.8e-06 27.4 0.2 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CDJ80546.1 - 7e-05 23.1 0.1 0.00035 20.9 0.0 2.2 3 0 0 3 3 3 1 GHMP kinases C terminal CxC1 PF18802.1 CDJ80546.1 - 0.077 13.2 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases LapA_dom PF06305.11 CDJ80547.1 - 0.2 11.5 1.4 0.32 10.9 0.3 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Nnf1 PF03980.14 CDJ80548.1 - 7.8e-05 23.0 0.5 0.00016 22.0 0.5 1.6 1 1 0 1 1 1 1 Nnf1 NurA PF09376.10 CDJ80548.1 - 0.057 13.1 0.2 0.064 12.9 0.2 1.1 1 0 0 1 1 1 0 NurA domain ProQ PF04352.13 CDJ80548.1 - 0.078 12.9 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 ProQ/FINO family DUF1804 PF08822.11 CDJ80548.1 - 0.15 12.0 1.6 0.81 9.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) FlaC_arch PF05377.11 CDJ80548.1 - 0.22 11.9 4.3 0.78 10.2 0.4 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Snf7 PF03357.21 CDJ80549.1 - 8.3e-31 106.9 21.7 1e-30 106.6 21.7 1.1 1 0 0 1 1 1 1 Snf7 CdvA PF18822.1 CDJ80549.1 - 0.002 18.0 2.7 0.002 18.0 2.7 3.1 2 1 1 3 3 3 1 CdvA-like coiled-coil domain YqaH PF17448.2 CDJ80549.1 - 0.0025 18.1 2.1 1.7 9.0 0.2 2.6 1 1 1 2 2 2 2 Uncharacterized YqaH-like LPD14 PF18827.1 CDJ80549.1 - 0.0029 17.8 2.2 0.0074 16.6 2.0 1.7 1 1 0 1 1 1 1 Large polyvalent protein-associated domain 14 PSD4 PF07631.11 CDJ80549.1 - 0.02 15.4 1.0 0.02 15.4 1.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1592) Spike_rec_bind PF09408.10 CDJ80549.1 - 0.049 13.4 0.2 0.068 12.9 0.2 1.2 1 0 0 1 1 1 0 Spike receptor binding domain DUF445 PF04286.12 CDJ80549.1 - 0.052 13.4 8.3 0.07 12.9 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) MqsR_toxin PF15723.5 CDJ80549.1 - 0.061 13.7 0.3 0.061 13.7 0.3 2.1 2 1 0 2 2 2 0 Motility quorum-sensing regulator, toxin of MqsA DUF5388 PF17363.2 CDJ80549.1 - 5.9 7.2 8.0 9 6.6 0.2 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5388) Cauli_VI PF01693.16 CDJ80550.1 - 1.5e-52 175.6 19.4 6.2e-20 71.2 2.9 3.3 3 0 0 3 3 3 3 Caulimovirus viroplasmin KTSC PF13619.6 CDJ80550.1 - 0.013 15.3 0.6 2.4 8.1 0.1 2.9 2 0 0 2 2 2 0 KTSC domain HycH PF07450.11 CDJ80550.1 - 0.091 13.1 0.0 2.7 8.4 0.0 2.5 2 1 0 2 2 2 0 Formate hydrogenlyase maturation protein HycH RNase_H PF00075.24 CDJ80551.1 - 3.1e-34 118.2 0.1 5.5e-34 117.4 0.0 1.5 2 0 0 2 2 2 1 RNase H Cauli_VI PF01693.16 CDJ80551.1 - 2e-18 66.4 1.1 4.2e-18 65.4 1.1 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.6 CDJ80551.1 - 0.0019 18.0 0.0 0.014 15.2 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase-like FRG2 PF15315.6 CDJ80551.1 - 0.43 10.7 4.1 0.73 10.0 4.1 1.3 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 RNase_H PF00075.24 CDJ80552.1 - 3.6e-18 66.1 0.3 6.2e-05 23.2 0.1 3.8 4 0 0 4 4 4 3 RNase H RVT_3 PF13456.6 CDJ80552.1 - 1.1e-07 31.7 0.0 0.0011 18.8 0.0 3.5 4 0 0 4 4 4 3 Reverse transcriptase-like TetR_C_24 PF17932.1 CDJ80552.1 - 0.019 15.3 0.5 2.4 8.4 0.1 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Mesd PF10185.9 CDJ80553.1 - 2e-49 167.5 3.1 2.3e-49 167.3 3.1 1.0 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor Rad54_N PF08658.10 CDJ80553.1 - 0.01 16.0 0.7 0.015 15.4 0.7 1.2 1 0 0 1 1 1 0 Rad54 N terminal SPG4 PF17325.2 CDJ80553.1 - 0.024 15.7 0.6 4 8.6 0.0 2.2 1 1 1 2 2 2 0 Stationary phase protein 4 TTSSLRR PF12468.8 CDJ80553.1 - 0.059 13.6 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein Sec8_exocyst PF04048.14 CDJ80554.1 - 0.0018 18.2 0.4 0.011 15.7 0.0 1.9 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain CHASE3 PF05227.13 CDJ80554.1 - 0.0055 16.6 5.2 0.048 13.6 1.4 2.2 1 1 1 2 2 2 2 CHASE3 domain LOH1CR12 PF10158.9 CDJ80554.1 - 0.037 14.1 1.2 1.1 9.2 0.3 2.5 1 1 2 3 3 3 0 Tumour suppressor protein Vps53_N PF04100.12 CDJ80554.1 - 0.045 12.7 0.9 0.1 11.5 0.6 1.6 1 1 1 2 2 2 0 Vps53-like, N-terminal TPR_20 PF14561.6 CDJ80554.1 - 0.045 14.1 2.1 0.4 11.0 0.1 2.7 2 2 0 2 2 2 0 Tetratricopeptide repeat NPV_P10 PF05531.12 CDJ80554.1 - 0.1 13.0 0.1 1.2 9.6 0.0 2.6 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF724 PF05266.14 CDJ80554.1 - 0.11 12.4 1.1 0.26 11.1 0.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Sec6 PF06046.13 CDJ80555.1 - 1.3e-92 311.1 0.7 2.1e-92 310.4 0.7 1.3 1 1 0 1 1 1 1 Exocyst complex component Sec6 PDZ_6 PF17820.1 CDJ80556.1 - 2.8e-08 33.5 0.0 5.5e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CDJ80556.1 - 2.9e-06 27.5 0.0 6.6e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ80556.1 - 5.4e-06 26.6 0.0 1.3e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain DUF2271 PF10029.9 CDJ80556.1 - 0.047 13.3 0.6 0.11 12.1 0.6 1.6 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) SCVP PF17619.2 CDJ80557.1 - 3.2e-23 82.4 0.2 3.7e-23 82.2 0.2 1.1 1 0 0 1 1 1 1 Secreted clade V proteins DUF2431 PF10354.9 CDJ80557.1 - 0.022 15.0 0.1 0.028 14.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) PriC PF07445.12 CDJ80557.1 - 0.16 11.9 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Primosomal replication protein priC RhlB PF12300.8 CDJ80558.1 - 0.025 14.7 0.6 0.038 14.1 0.6 1.3 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB SPRY PF00622.28 CDJ80559.1 - 1.6e-11 44.3 0.0 2.2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 SPRY domain Big_6 PF17936.1 CDJ80559.1 - 0.057 13.7 0.9 0.073 13.4 0.1 1.5 2 0 0 2 2 2 0 Bacterial Ig domain Mannosyl_trans PF05007.13 CDJ80560.1 - 2.1e-67 227.8 15.1 3.6e-67 226.9 15.1 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) Ribosomal_L23 PF00276.20 CDJ80560.1 - 1.5e-08 34.9 0.1 3.5e-08 33.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 RRM_3 PF08777.11 CDJ80560.1 - 0.0048 16.9 0.4 0.0087 16.1 0.4 1.4 1 0 0 1 1 1 1 RNA binding motif TP_methylase PF00590.20 CDJ80561.1 - 2e-23 83.4 0.0 4.3e-23 82.4 0.0 1.5 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases ZNRF_3_ecto PF18212.1 CDJ80561.1 - 0.02 14.9 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 ZNRF-3 Ectodomain GST_N_4 PF17172.4 CDJ80562.1 - 4.2e-22 78.7 0.0 7.4e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 CDJ80562.1 - 1.6e-20 72.6 0.4 1.5e-19 69.6 0.0 2.7 4 0 0 4 4 4 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDJ80562.1 - 1.7e-06 28.0 0.0 7.2e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 CDJ80562.1 - 8.3e-05 22.9 0.0 0.00025 21.3 0.0 1.8 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.6 CDJ80562.1 - 0.0005 20.2 0.0 0.00091 19.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDJ80562.1 - 0.0025 18.0 0.0 0.0052 17.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3776 PF12618.8 CDJ80563.1 - 0.29 11.7 8.0 0.53 10.9 2.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3776) Pkinase PF00069.25 CDJ80564.1 - 5e-63 212.9 0.0 6.7e-63 212.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DCX PF03607.17 CDJ80564.1 - 5.6e-31 106.4 0.0 3e-15 56.1 0.0 2.6 2 0 0 2 2 2 2 Doublecortin Pkinase_Tyr PF07714.17 CDJ80564.1 - 6.2e-26 91.2 0.0 8.7e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ80564.1 - 1.1e-05 25.0 0.0 0.00037 19.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CDJ80564.1 - 8.7e-05 21.5 0.0 0.0002 20.3 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 CDJ80564.1 - 0.021 14.4 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Alfin PF12165.8 CDJ80564.1 - 0.044 13.4 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 Alfin Kdo PF06293.14 CDJ80564.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIA_gamma_N PF02268.16 CDJ80566.1 - 7.4e-18 64.3 0.2 1.1e-17 63.7 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 CDJ80566.1 - 5.7e-16 58.4 1.1 8.9e-16 57.8 1.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit AMOP PF03782.17 CDJ80567.1 - 3e-43 147.4 5.6 5.3e-43 146.6 5.6 1.4 1 0 0 1 1 1 1 AMOP domain NIDO PF06119.14 CDJ80567.1 - 3.8e-24 85.4 0.1 9.8e-24 84.1 0.1 1.8 1 0 0 1 1 1 1 Nidogen-like VWD PF00094.25 CDJ80567.1 - 1.7e-15 57.6 0.1 7.1e-10 39.4 0.0 2.8 2 0 0 2 2 2 2 von Willebrand factor type D domain Sushi PF00084.20 CDJ80567.1 - 0.0004 20.9 0.9 0.0004 20.9 0.9 2.2 2 0 0 2 2 2 1 Sushi repeat (SCR repeat) Acetyltransf_10 PF13673.7 CDJ80568.1 - 0.0017 18.3 0.0 0.004 17.1 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDJ80568.1 - 0.0024 18.3 0.0 0.0041 17.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDJ80568.1 - 0.079 13.2 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family PTS_EIIA_1 PF00358.20 CDJ80568.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Arrestin_N PF00339.29 CDJ80569.1 - 3.6e-43 147.1 0.7 2.4e-42 144.5 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CDJ80569.1 - 4.3e-25 88.7 1.7 2e-19 70.4 1.7 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.15 CDJ80569.1 - 0.0034 16.5 0.0 0.011 14.8 0.0 1.8 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Rgp1 PF08737.10 CDJ80569.1 - 0.006 15.8 0.0 0.37 9.9 0.0 2.2 2 0 0 2 2 2 2 Rgp1 DUF922 PF06037.11 CDJ80569.1 - 0.071 12.9 0.3 0.12 12.2 0.3 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) YIF1 PF03878.15 CDJ80570.1 - 3.6e-29 102.0 8.8 4e-29 101.8 8.8 1.0 1 0 0 1 1 1 1 YIF1 Cation_ATPase_C PF00689.21 CDJ80570.1 - 0.99 9.1 10.3 1.5 8.5 10.3 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus tRNA_int_endo PF01974.17 CDJ80571.1 - 1.4e-18 66.7 0.0 2.7e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Transpeptidase PF00905.22 CDJ80571.1 - 0.18 11.0 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Penicillin binding protein transpeptidase domain Srg PF02118.21 CDJ80573.1 - 0.00014 21.6 2.2 0.00017 21.4 2.2 1.1 1 0 0 1 1 1 1 Srg family chemoreceptor Thioredoxin_9 PF14595.6 CDJ80573.1 - 0.034 13.9 0.1 0.043 13.6 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin DsbD_2 PF13386.6 CDJ80574.1 - 0.013 15.4 0.3 0.019 14.9 0.3 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region Srg PF02118.21 CDJ80576.1 - 0.0001 22.1 5.3 0.00012 21.8 5.3 1.0 1 0 0 1 1 1 1 Srg family chemoreceptor 7tm_1 PF00001.21 CDJ80576.1 - 0.00083 18.8 2.1 0.00095 18.6 2.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srh PF10318.9 CDJ80576.1 - 0.023 13.7 1.3 0.023 13.7 1.3 1.9 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srh DUF2975 PF11188.8 CDJ80576.1 - 0.079 12.9 5.9 0.16 11.8 4.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) Pkinase PF00069.25 CDJ80577.1 - 3.2e-23 82.4 2.0 1.6e-17 63.8 0.0 3.9 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ80577.1 - 1.9e-13 50.3 1.7 4e-12 46.0 0.0 3.5 2 1 0 3 3 3 1 Protein tyrosine kinase FMO-like PF00743.19 CDJ80577.1 - 0.002 16.6 0.1 1.5 7.1 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like TipE PF16972.5 CDJ80577.1 - 1.2 8.2 6.6 4.9 6.2 0.9 2.5 2 0 0 2 2 2 0 Na+ channel auxiliary subunit TipE 2OG-FeII_Oxy_2 PF13532.6 CDJ80578.1 - 1.1e-09 38.8 0.1 3e-09 37.3 0.1 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 CDJ80578.1 - 0.16 12.4 0.0 0.29 11.6 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily PHD PF00628.29 CDJ80580.1 - 1.8e-22 78.9 71.0 4.2e-09 36.2 9.9 6.7 5 1 1 6 6 6 5 PHD-finger SET PF00856.28 CDJ80580.1 - 8e-18 65.4 0.0 5.1e-17 62.8 0.0 2.5 1 1 0 1 1 1 1 SET domain FYRC PF05965.14 CDJ80580.1 - 1e-16 60.9 0.0 2.6e-16 59.5 0.0 1.8 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 CDJ80580.1 - 2.1e-16 59.5 0.6 4.1e-16 58.6 0.1 1.9 2 0 0 2 2 2 1 F/Y-rich N-terminus zf-HC5HC2H PF13771.6 CDJ80580.1 - 2.3e-09 37.4 6.3 2.3e-09 37.4 6.3 6.2 3 1 2 5 5 5 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CDJ80580.1 - 1e-08 35.3 7.2 1e-08 35.3 7.2 5.7 3 2 3 6 6 6 1 PHD-zinc-finger like domain HMG_box_2 PF09011.10 CDJ80580.1 - 0.0057 17.2 0.5 0.015 15.9 0.5 1.7 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 CDJ80580.1 - 0.18 12.3 0.5 0.47 10.9 0.5 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box Lustrin_cystein PF14625.6 CDJ80581.1 - 9.9e-12 45.0 28.9 0.00013 22.2 7.2 3.9 4 0 0 4 4 4 3 Lustrin, cysteine-rich repeated domain HSP20 PF00011.21 CDJ80582.1 - 3.3e-23 81.8 0.0 3.7e-23 81.6 0.0 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ80582.1 - 5.7e-05 22.6 0.0 8.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 CDJ80582.1 - 0.06 14.4 0.1 0.076 14.0 0.1 1.2 1 0 0 1 1 1 0 CS domain ASH PF15780.5 CDJ80582.1 - 0.14 12.4 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin zf-C4 PF00105.18 CDJ80583.1 - 1.8e-27 95.6 11.0 3.3e-27 94.8 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ80583.1 - 0.00051 19.7 0.0 0.00086 18.9 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Fringe PF02434.16 CDJ80584.1 - 7.7e-05 22.2 0.1 0.00087 18.8 0.1 2.4 2 1 0 2 2 2 1 Fringe-like Galactosyl_T PF01762.21 CDJ80584.1 - 0.00059 19.7 0.0 0.38 10.6 0.0 2.1 1 1 1 2 2 2 2 Galactosyltransferase RNase_PH PF01138.21 CDJ80585.1 - 3.8e-16 59.8 0.0 5.6e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Y_phosphatase PF00102.27 CDJ80586.1 - 1.6e-64 217.7 0.3 2.1e-64 217.3 0.3 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ80586.1 - 2.4e-08 33.9 0.1 4.9e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDJ80586.1 - 0.00083 19.4 0.1 0.002 18.2 0.1 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CDJ80586.1 - 0.039 14.1 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 Inositol hexakisphosphate PIG-S PF10510.9 CDJ80589.1 - 8.8e-48 163.4 0.2 1.2e-47 163.0 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Tetraspanin PF00335.20 CDJ80590.1 - 4.6e-58 196.6 8.3 5.9e-58 196.3 8.3 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF308 PF03729.13 CDJ80590.1 - 0.018 15.3 14.1 3.4 8.1 0.6 3.2 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) DUF1129 PF06570.11 CDJ80590.1 - 0.079 12.4 5.0 0.29 10.6 0.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) DUF1218 PF06749.12 CDJ80590.1 - 4.3 7.9 8.6 2.3 8.8 0.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) YiaAB PF05360.14 CDJ80590.1 - 4.6 7.6 11.1 0.71 10.2 0.4 3.2 3 0 0 3 3 3 0 yiaA/B two helix domain DUF872 PF05915.12 CDJ80590.1 - 5.1 7.3 6.6 5.4 7.2 2.9 2.4 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF3040 PF11239.8 CDJ80590.1 - 9.9 6.5 9.4 9.7 6.5 3.7 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) CPSase_L_D2 PF02786.17 CDJ80591.1 - 1.7e-25 89.8 0.2 2.2e-25 89.4 0.2 1.1 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 CDJ80591.1 - 9.5e-13 48.1 0.2 1.4e-12 47.5 0.2 1.2 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 CDJ80591.1 - 7.7e-09 35.4 0.3 1.2e-08 34.7 0.3 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 CDJ80591.1 - 2.5e-07 30.9 0.1 3.6e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 CDJ80591.1 - 7.1e-06 25.8 0.4 2.3e-05 24.2 0.4 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.11 CDJ80591.1 - 1.3e-05 24.8 0.1 2.2e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain MGS PF02142.22 CDJ80591.1 - 0.0016 18.6 0.0 0.0059 16.8 0.0 2.0 2 0 0 2 2 2 1 MGS-like domain GSH-S_ATP PF02955.16 CDJ80591.1 - 0.0031 16.9 0.0 0.005 16.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain GARS_A PF01071.19 CDJ80591.1 - 0.006 16.4 0.3 0.013 15.2 0.3 1.6 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TFIIB PF00382.19 CDJ80592.1 - 2.5e-43 146.0 8.4 1e-21 76.7 1.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Glyco_tran_28_C PF04101.16 CDJ80592.1 - 4.4e-25 88.6 0.4 1e-24 87.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain TF_Zn_Ribbon PF08271.12 CDJ80592.1 - 8.3e-13 47.6 2.0 8.4e-13 47.6 0.3 2.0 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_N PF00134.23 CDJ80592.1 - 1.2e-08 34.8 0.3 9.6e-06 25.4 0.1 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 CDJ80592.1 - 0.011 15.8 0.6 1.3 9.1 0.0 2.5 1 1 1 2 2 2 0 Cyclin, C-terminal domain RB_B PF01857.20 CDJ80592.1 - 0.04 13.9 0.2 0.14 12.2 0.3 1.9 1 1 1 2 2 2 0 Retinoblastoma-associated protein B domain THAP PF05485.12 CDJ80593.1 - 1.3e-14 54.8 0.3 0.00031 21.6 0.1 3.7 3 1 0 3 3 3 3 THAP domain DUF1540 PF07561.11 CDJ80593.1 - 1.8 8.9 13.2 0.14 12.4 2.5 3.7 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1540) Fringe PF02434.16 CDJ80594.1 - 4.5e-42 144.2 0.0 7.5e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 CDJ80594.1 - 0.16 11.8 0.0 14 5.4 0.0 2.7 2 1 1 3 3 3 0 Galactosyltransferase Rab5ip PF07019.12 CDJ80595.1 - 4.2e-14 52.9 5.6 5.6e-14 52.5 5.6 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Clc-like PF07062.12 CDJ80595.1 - 0.061 12.8 2.2 0.076 12.5 2.2 1.1 1 0 0 1 1 1 0 Clc-like Antirestrict PF03230.13 CDJ80596.1 - 0.081 13.0 0.2 0.1 12.7 0.2 1.1 1 0 0 1 1 1 0 Antirestriction protein DUF1297 PF06973.12 CDJ80596.1 - 0.13 11.8 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) NicO PF03824.16 CDJ80597.1 - 8.4 5.6 9.7 10 5.3 9.7 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF1759 PF03564.15 CDJ80598.1 - 1.1e-14 54.7 0.0 1.8e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) SepF PF04472.12 CDJ80598.1 - 0.13 12.6 0.0 11 6.4 0.0 2.4 2 0 0 2 2 2 0 Cell division protein SepF Sulfotransfer_1 PF00685.27 CDJ80599.1 - 8.4e-60 202.5 0.0 1.2e-59 202.0 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CDJ80599.1 - 3.5e-08 34.1 0.0 0.00011 22.7 0.0 2.4 1 1 0 2 2 2 2 Sulfotransferase family 5_nucleotid PF05761.14 CDJ80601.1 - 2.8e-136 455.1 2.6 3.5e-136 454.7 2.6 1.1 1 0 0 1 1 1 1 5' nucleotidase family DIM1 PF02966.16 CDJ80601.1 - 0.05 13.4 0.3 0.14 11.9 0.1 1.9 2 0 0 2 2 2 0 Mitosis protein DIM1 JIP_LZII PF16471.5 CDJ80601.1 - 0.059 13.5 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II DUF4293 PF14126.6 CDJ80602.1 - 0.054 13.8 0.2 0.079 13.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) Pacs-1 PF10254.9 CDJ80604.1 - 1.2e-58 199.1 0.0 2.3e-58 198.2 0.0 1.5 1 0 0 1 1 1 1 PACS-1 cytosolic sorting protein DUF695 PF05117.12 CDJ80604.1 - 0.072 13.3 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF695) TUDOR PF00567.24 CDJ80605.1 - 3.8e-10 39.8 0.0 9.4e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Tudor domain Collagen PF01391.18 CDJ80606.1 - 7.2e-25 86.5 79.2 5.3e-10 38.9 31.5 4.2 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ80606.1 - 0.00017 21.6 0.9 0.00027 21.0 0.9 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Calponin PF00402.18 CDJ80607.1 - 2.6e-61 202.8 32.2 1.9e-13 49.8 2.2 7.3 7 0 0 7 7 7 7 Calponin family repeat TPR_2 PF07719.17 CDJ80608.1 - 4.5e-24 82.6 10.9 0.011 15.8 0.0 9.2 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ80608.1 - 1.2e-15 57.6 13.8 4.9e-05 23.5 0.1 6.4 3 2 4 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ80608.1 - 1e-14 53.9 2.7 0.61 11.0 0.1 7.9 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ80608.1 - 6.6e-13 47.9 9.2 0.21 11.4 0.2 8.1 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ80608.1 - 4.8e-12 46.2 7.7 0.00084 19.8 0.0 5.8 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ80608.1 - 8.6e-12 45.5 2.7 0.00083 20.0 0.0 5.5 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ80608.1 - 4.9e-10 38.8 4.5 0.65 10.4 0.0 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ80608.1 - 1.1e-06 28.6 7.9 0.75 10.3 0.0 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ80608.1 - 1.2e-06 28.2 0.3 0.49 10.3 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ80608.1 - 2.7e-06 27.0 4.5 4 7.7 0.1 6.5 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ80608.1 - 3.5e-06 27.3 7.3 0.12 13.0 0.0 6.8 9 0 0 9 9 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ80608.1 - 0.0019 17.8 0.0 0.0019 17.8 0.0 4.4 6 1 0 6 6 6 1 TPR repeat TPR_MalT PF17874.1 CDJ80608.1 - 0.0023 17.4 3.4 0.014 14.8 0.4 2.6 2 1 0 2 2 2 1 MalT-like TPR region TPR_15 PF13429.6 CDJ80608.1 - 0.0033 16.7 2.1 3.4 6.8 0.0 4.0 1 1 3 4 4 4 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 CDJ80608.1 - 0.0035 17.3 0.1 0.01 15.8 0.1 1.8 1 0 0 1 1 1 1 Virulence factor membrane-bound polymerase, C-terminal TPR_9 PF13371.6 CDJ80608.1 - 0.023 14.8 3.7 37 4.6 0.2 4.6 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 CDJ80608.1 - 0.052 13.9 0.2 4.1 7.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ80608.1 - 0.063 13.5 17.0 3.9 7.8 3.4 4.9 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 CDJ80608.1 - 0.069 13.8 0.0 25 5.9 0.0 4.2 5 0 0 5 5 3 0 Tetratricopeptide repeat Coatomer_E PF04733.14 CDJ80608.1 - 0.095 12.1 0.3 5.1 6.4 0.0 3.1 2 2 2 4 4 4 0 Coatomer epsilon subunit Fis1_TPR_C PF14853.6 CDJ80608.1 - 0.49 10.5 4.0 4.6 7.4 0.0 3.7 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat G_glu_transpept PF01019.21 CDJ80609.1 - 1.7e-113 380.1 0.0 1.9e-113 379.9 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase MSP7_C PF12948.7 CDJ80609.1 - 0.073 13.7 0.1 0.18 12.5 0.1 1.6 1 0 0 1 1 1 0 MSP7-like protein C-terminal domain G_glu_transpept PF01019.21 CDJ80610.1 - 1.3e-159 532.2 0.1 1.5e-159 532.0 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Sh_2 PF17512.2 CDJ80610.1 - 0.11 12.2 0.2 0.25 11.1 0.2 1.5 1 0 0 1 1 1 0 Metapneumovirus Small hydrophobic protein EB PF01683.18 CDJ80611.1 - 0.9 9.9 31.2 1.3 9.3 3.8 3.5 2 2 1 3 3 3 0 EB module zf-C2H2_4 PF13894.6 CDJ80612.1 - 8.3e-10 38.7 49.9 0.0042 17.8 2.1 6.2 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2 PF00096.26 CDJ80612.1 - 2.1e-07 31.0 57.1 0.0004 20.7 3.7 6.2 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ80612.1 - 0.0026 18.1 5.8 0.0026 18.1 5.8 5.4 6 0 0 6 6 6 1 Zinc-finger double domain zf-Sec23_Sec24 PF04810.15 CDJ80612.1 - 0.016 15.3 0.8 0.016 15.3 0.8 4.4 5 0 0 5 5 5 0 Sec23/Sec24 zinc finger zf-met PF12874.7 CDJ80612.1 - 0.16 12.4 1.1 0.16 12.4 1.1 5.8 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-CHCC PF10276.9 CDJ80612.1 - 2.2 8.4 9.0 66 3.7 0.0 4.2 4 0 0 4 4 4 0 Zinc-finger domain zinc_ribbon_15 PF17032.5 CDJ80612.1 - 3.9 8.3 20.1 0.89 10.3 1.9 3.2 2 1 0 2 2 2 0 zinc-ribbon family RVT_1 PF00078.27 CDJ80613.1 - 0.037 13.6 0.0 0.037 13.6 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Spc7 PF08317.11 CDJ80614.1 - 0.0043 16.0 0.8 0.0047 15.9 0.8 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein Abhydrolase_5 PF12695.7 CDJ80615.1 - 0.089 12.5 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family RVT_1 PF00078.27 CDJ80616.1 - 7.8e-33 113.9 0.0 1.2e-32 113.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HSP20 PF00011.21 CDJ80617.1 - 3.3e-23 81.8 0.0 3.7e-23 81.6 0.0 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ80617.1 - 5.7e-05 22.6 0.0 8.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 CDJ80617.1 - 0.06 14.4 0.1 0.076 14.0 0.1 1.2 1 0 0 1 1 1 0 CS domain ASH PF15780.5 CDJ80617.1 - 0.14 12.4 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin I-set PF07679.16 CDJ80618.1 - 8.1e-56 186.1 0.0 2.8e-18 65.8 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ80618.1 - 9.7e-39 131.8 0.0 9.9e-12 45.3 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 CDJ80618.1 - 8.1e-22 77.4 0.0 2.2e-08 34.3 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 CDJ80618.1 - 1.1e-19 70.3 0.0 3.1e-07 30.5 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 CDJ80618.1 - 6.3e-10 39.2 0.0 0.045 13.9 0.0 3.8 3 2 0 3 3 3 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDJ80618.1 - 9e-08 32.1 0.0 0.12 12.5 0.0 3.4 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.12 CDJ80618.1 - 5.6e-06 26.3 0.0 0.11 12.5 0.0 3.7 3 1 0 3 3 3 2 Penicillin-Binding Protein C-terminus Family Ig_C17orf99 PF17736.1 CDJ80618.1 - 0.00018 21.5 0.0 0.66 10.1 0.0 3.3 3 0 0 3 3 3 1 C17orf99 Ig domain V-set_CD47 PF08204.11 CDJ80618.1 - 0.007 16.3 0.0 0.05 13.6 0.0 2.3 3 0 0 3 3 3 1 CD47 immunoglobulin-like domain Ig_4 PF16680.5 CDJ80618.1 - 0.0072 16.6 0.0 3.5 8.0 0.0 2.6 2 0 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 CDJ80618.1 - 0.02 15.3 0.0 2.2 8.7 0.0 2.7 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain UPF0561 PF10573.9 CDJ80618.1 - 0.044 13.9 1.0 0.093 12.9 1.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 Izumo-Ig PF16706.5 CDJ80618.1 - 0.085 12.9 0.0 58 3.9 0.0 3.2 3 1 0 3 3 3 0 Izumo-like Immunoglobulin domain Innexin PF00876.18 CDJ80619.1 - 1.8e-109 366.3 9.8 2.2e-109 366.0 9.8 1.0 1 0 0 1 1 1 1 Innexin AAA PF00004.29 CDJ80620.1 - 9.4e-39 132.9 0.0 2.3e-38 131.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ80620.1 - 4.9e-10 39.1 0.1 1.4e-09 37.6 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 CDJ80620.1 - 1.9e-07 31.0 0.0 0.00023 21.0 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CDJ80620.1 - 2.6e-05 24.2 0.2 8.7e-05 22.5 0.2 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 CDJ80620.1 - 0.001 18.4 0.0 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 CDJ80620.1 - 0.0017 18.6 2.3 0.1 12.9 0.1 3.6 2 1 2 4 4 4 1 AAA domain AAA_16 PF13191.6 CDJ80620.1 - 0.0044 17.4 1.2 0.029 14.8 0.5 2.5 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 CDJ80620.1 - 0.029 13.7 0.0 0.086 12.2 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 CDJ80620.1 - 0.049 13.7 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 CDJ80620.1 - 0.096 13.2 0.0 0.28 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CDJ80620.1 - 0.17 12.2 0.1 0.47 10.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain Ndc1_Nup PF09531.10 CDJ80621.1 - 3.2e-30 105.4 34.0 5.6e-28 98.0 34.0 3.5 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup RGS PF00615.19 CDJ80622.1 - 1e-28 100.0 1.7 1.4e-28 99.6 1.7 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain SAICAR_synt PF01259.18 CDJ80622.1 - 0.013 15.1 0.1 0.017 14.8 0.1 1.3 1 0 0 1 1 1 0 SAICAR synthetase LEDGF PF11467.8 CDJ80622.1 - 0.016 14.8 0.5 0.027 14.1 0.4 1.4 1 1 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) Glyco_hydro_1 PF00232.18 CDJ80622.1 - 0.021 13.2 0.1 0.024 13.0 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 DUF1759 PF03564.15 CDJ80623.1 - 7e-18 65.0 0.2 1.4e-17 64.0 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1759) PMM PF03332.13 CDJ80623.1 - 0.002 17.9 0.3 0.0042 16.9 0.3 1.5 1 1 0 1 1 1 1 Eukaryotic phosphomannomutase PP2C_C PF07830.13 CDJ80623.1 - 0.11 13.0 1.5 0.34 11.4 0.8 2.2 1 1 1 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain DUF1759 PF03564.15 CDJ80624.1 - 2.5e-12 46.9 0.1 2.7e-09 37.1 0.0 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF1759) gag-asp_proteas PF13975.6 CDJ80625.1 - 4e-08 33.7 0.0 1e-07 32.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ80625.1 - 6.8e-07 29.8 0.0 1.6e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ80625.1 - 5e-06 26.8 2.6 6.5e-05 23.2 0.1 2.5 1 1 1 2 2 2 1 Retroviral aspartyl protease Mvb12 PF09452.10 CDJ80625.1 - 0.084 13.3 0.8 0.99 9.9 0.0 2.4 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 Asp_protease PF09668.10 CDJ80625.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease HTH_48 PF17906.1 CDJ80628.1 - 1.4e-17 63.5 0.1 2.4e-17 62.8 0.1 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_23 PF13384.6 CDJ80628.1 - 8.2e-07 28.7 0.3 0.055 13.3 0.0 2.4 2 0 0 2 2 2 2 Homeodomain-like domain HTH_AsnC-type PF13404.6 CDJ80628.1 - 2.2e-06 27.4 0.3 2.2e-06 27.4 0.3 1.5 2 0 0 2 2 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 CDJ80628.1 - 3.3e-06 26.5 0.0 5.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Tnp_IS630 PF01710.16 CDJ80628.1 - 1.9e-05 24.7 0.0 2.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_50 PF18024.1 CDJ80628.1 - 4e-05 23.1 0.1 7.7e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 CDJ80628.1 - 5.6e-05 23.2 0.2 0.21 11.8 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_32 PF13565.6 CDJ80628.1 - 0.00016 22.2 0.1 0.00024 21.7 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain MarR PF01047.22 CDJ80628.1 - 0.00017 21.5 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 CDJ80628.1 - 0.00041 20.2 0.1 0.00064 19.5 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_10 PF04967.12 CDJ80628.1 - 0.0018 18.0 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 HTH DNA binding domain HTH_27 PF13463.6 CDJ80628.1 - 0.0041 17.6 0.1 0.0072 16.8 0.1 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain LZ_Tnp_IS481 PF13011.6 CDJ80628.1 - 0.0041 17.6 1.9 1.4 9.5 0.3 2.2 1 1 1 2 2 2 2 leucine-zipper of insertion element IS481 HTH_Tnp_ISL3 PF13542.6 CDJ80628.1 - 0.0046 16.3 0.3 0.25 10.8 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 CDJ80628.1 - 0.0049 16.9 0.1 0.91 9.6 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_11 PF08279.12 CDJ80628.1 - 0.008 16.1 0.3 0.031 14.2 0.0 1.9 2 0 0 2 2 2 1 HTH domain HTH_1 PF00126.27 CDJ80628.1 - 0.039 13.9 0.1 0.13 12.3 0.1 2.0 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Terminase_5 PF06056.12 CDJ80628.1 - 0.045 13.6 0.1 2.5 8.0 0.0 2.3 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) Sigma70_r4_2 PF08281.12 CDJ80628.1 - 0.05 13.3 0.1 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 LacI PF00356.21 CDJ80628.1 - 0.066 13.0 0.0 0.16 11.8 0.0 1.7 2 0 0 2 2 1 0 Bacterial regulatory proteins, lacI family DUF746 PF05344.11 CDJ80628.1 - 0.072 12.9 0.2 12 5.8 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) HTH_30 PF13556.6 CDJ80628.1 - 0.075 12.8 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Sigma70_r4 PF04545.16 CDJ80628.1 - 0.083 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 DDRGK PF09756.9 CDJ80628.1 - 0.083 12.5 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 DDRGK domain Phage_antitermQ PF06530.12 CDJ80628.1 - 0.097 12.6 0.2 0.76 9.7 0.1 1.9 2 0 0 2 2 2 0 Phage antitermination protein Q HlyIII PF03006.20 CDJ80631.1 - 3.3e-70 236.3 19.0 4.1e-70 236.0 19.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 CDJ80631.1 - 0.037 14.1 0.3 0.13 12.4 0.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF962) SPW PF03779.14 CDJ80631.1 - 0.1 12.2 0.0 0.1 12.2 0.0 2.9 3 0 0 3 3 3 0 SPW repeat Fijivirus_P9-2 PF06837.11 CDJ80631.1 - 7.3 6.0 6.2 14 5.1 6.2 1.4 1 0 0 1 1 1 0 Fijivirus P9-2 protein Ribosomal_L18A PF01775.17 CDJ80632.1 - 1.2e-11 44.8 0.3 1.9e-11 44.1 0.3 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A RVT_1 PF00078.27 CDJ80634.1 - 1.7e-07 31.0 0.0 2.5e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SH2 PF00017.24 CDJ80635.1 - 2.4e-18 66.0 0.0 3.8e-09 36.5 0.0 2.5 2 0 0 2 2 2 2 SH2 domain SH3_9 PF14604.6 CDJ80635.1 - 0.00033 20.5 0.2 0.00083 19.2 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH2_2 PF14633.6 CDJ80635.1 - 0.039 13.3 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 SH2 domain SH3_1 PF00018.28 CDJ80635.1 - 0.059 13.0 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 SH3 domain RhoGAP PF00620.27 CDJ80635.1 - 0.14 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 RhoGAP domain Esterase PF00756.20 CDJ80636.1 - 3.2e-50 171.1 0.0 3.7e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 CDJ80636.1 - 0.00017 21.2 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CDJ80636.1 - 0.0002 20.7 0.0 0.0003 20.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 CDJ80636.1 - 0.00056 18.9 0.0 0.00081 18.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_3 PF07859.13 CDJ80636.1 - 0.0048 16.8 0.0 0.2 11.5 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ80636.1 - 0.0081 16.8 0.0 0.0098 16.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 CDJ80636.1 - 0.028 13.1 0.0 0.034 12.8 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 CDJ80636.1 - 0.038 13.5 0.0 0.26 10.7 0.0 1.9 1 1 0 1 1 1 0 Esterase PHB depolymerase Lipase_3 PF01764.25 CDJ80636.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Motile_Sperm PF00635.26 CDJ80637.1 - 2.1e-18 66.2 0.7 5.2e-18 64.9 0.6 1.8 1 1 0 1 1 1 1 MSP (Major sperm protein) domain DUF2407_C PF13373.6 CDJ80637.1 - 0.054 13.7 0.2 0.14 12.3 0.2 1.7 1 0 0 1 1 1 0 DUF2407 C-terminal domain Ndc1_Nup PF09531.10 CDJ80637.1 - 0.84 8.2 11.4 1.2 7.8 11.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Borrelia_P83 PF05262.11 CDJ80637.1 - 2.8 6.3 15.9 3.5 6.0 15.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC27 PF09507.10 CDJ80637.1 - 4.2 6.6 30.9 6.5 6.0 30.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Neur_chan_LBD PF02931.23 CDJ80638.1 - 1.2e-39 136.0 5.1 1.8e-39 135.5 5.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ80638.1 - 1.4e-22 81.0 1.9 1.4e-21 77.6 0.3 2.1 1 1 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Cornichon PF03311.14 CDJ80639.1 - 0.0043 17.4 0.2 0.0056 17.0 0.2 1.2 1 0 0 1 1 1 1 Cornichon protein PRKCSH-like PF12999.7 CDJ80640.1 - 6.6e-40 136.8 7.9 6.6e-40 136.8 7.9 2.0 2 1 1 3 3 3 1 Glucosidase II beta subunit-like EF-hand_1 PF00036.32 CDJ80640.1 - 9.4e-07 28.0 0.7 0.0022 17.4 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CDJ80640.1 - 9e-06 25.0 1.5 0.039 13.5 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CDJ80640.1 - 1.6e-05 24.5 0.7 0.011 15.7 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain Ldl_recept_a PF00057.18 CDJ80640.1 - 0.00054 20.1 18.9 0.0064 16.7 2.8 2.9 2 1 0 2 2 2 2 Low-density lipoprotein receptor domain class A PRKCSH_1 PF13015.6 CDJ80640.1 - 0.0049 16.6 0.2 0.011 15.4 0.2 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 CDJ80640.1 - 0.012 16.6 1.3 0.012 16.6 1.3 3.1 3 1 0 3 3 3 0 Glucosidase II beta subunit-like protein EF-hand_8 PF13833.6 CDJ80640.1 - 0.016 15.0 2.5 3.9 7.4 0.5 2.7 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_7 PF13499.6 CDJ80640.1 - 0.043 14.3 0.6 0.043 14.3 0.6 3.3 2 1 1 3 3 3 0 EF-hand domain pair DnaJ_C PF01556.18 CDJ80641.1 - 3.7e-28 98.5 0.6 4.9e-28 98.1 0.6 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CDJ80641.1 - 8.6e-26 89.8 2.6 1.3e-25 89.3 2.6 1.3 1 0 0 1 1 1 1 DnaJ domain zf-UBP PF02148.19 CDJ80642.1 - 1.4e-07 31.7 6.8 2.5e-07 30.9 6.8 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein KxDL PF10241.9 CDJ80643.1 - 0.0031 17.7 3.6 0.0043 17.3 3.6 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein WXG100 PF06013.12 CDJ80643.1 - 0.0083 16.3 0.2 0.011 16.0 0.2 1.3 1 0 0 1 1 1 1 Proteins of 100 residues with WXG DUF1839 PF08893.10 CDJ80643.1 - 0.019 14.2 0.8 0.025 13.8 0.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1839) Cnn_1N PF07989.11 CDJ80643.1 - 0.1 12.7 10.1 0.093 12.9 9.1 1.5 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 Halo_GVPC PF05465.13 CDJ80643.1 - 0.13 12.6 2.0 5.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat DUF4407 PF14362.6 CDJ80643.1 - 0.14 11.5 2.5 0.15 11.4 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Com_YlbF PF06133.11 CDJ80643.1 - 0.14 12.8 13.0 0.087 13.4 10.5 1.8 1 1 1 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA CALCOCO1 PF07888.11 CDJ80643.1 - 0.19 10.5 11.3 0.35 9.7 11.3 1.4 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like GIT_CC PF16559.5 CDJ80643.1 - 0.37 10.7 3.7 0.78 9.6 0.3 2.4 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor 5_nucleotid PF05761.14 CDJ80643.1 - 0.4 9.5 5.8 0.47 9.3 5.8 1.0 1 0 0 1 1 1 0 5' nucleotidase family TMPIT PF07851.13 CDJ80643.1 - 1.2 8.3 4.0 1.3 8.2 4.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Histone_HNS PF00816.21 CDJ80643.1 - 1.7 9.5 7.0 2.7 8.9 7.0 1.4 1 1 0 1 1 1 0 H-NS histone family GrpE PF01025.19 CDJ80643.1 - 1.8 8.2 9.3 2.5 7.8 9.3 1.4 1 1 0 1 1 1 0 GrpE OmpH PF03938.14 CDJ80643.1 - 2.1 8.7 12.9 3.5 8.0 12.9 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Fzo_mitofusin PF04799.13 CDJ80643.1 - 2.7 7.5 7.1 7.3 6.1 6.8 1.7 1 1 0 1 1 1 0 fzo-like conserved region DivIC PF04977.15 CDJ80643.1 - 3.6 7.4 9.3 0.18 11.6 2.2 2.2 1 1 1 2 2 2 0 Septum formation initiator EMC3_TMCO1 PF01956.16 CDJ80643.1 - 6.6 6.4 6.1 7.5 6.3 6.1 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Rx_N PF18052.1 CDJ80643.1 - 7 7.0 8.8 4 7.8 1.2 2.0 1 1 1 2 2 2 0 Rx N-terminal domain RVT_1 PF00078.27 CDJ80644.1 - 1.7e-45 155.3 0.0 2.8e-45 154.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CDJ80644.1 - 3.4e-07 30.0 0.0 1.5e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CDJ80644.1 - 0.00018 21.3 0.0 0.00056 19.7 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF1759 PF03564.15 CDJ80645.1 - 5e-22 78.4 0.2 3.4e-21 75.7 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 CDJ80645.1 - 7.6e-14 51.8 0.1 1.7e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Spc7 PF08317.11 CDJ80645.1 - 9.5e-05 21.4 0.7 0.00022 20.2 0.7 1.6 1 0 0 1 1 1 1 Spc7 kinetochore protein Asp_protease_2 PF13650.6 CDJ80645.1 - 0.00059 20.4 0.2 0.0015 19.2 0.2 1.7 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ80645.1 - 0.0067 17.0 0.0 0.017 15.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotran_gag_2 PF14223.6 CDJ80645.1 - 0.03 14.0 0.3 0.2 11.3 0.0 2.4 2 1 0 2 2 2 0 gag-polypeptide of LTR copia-type PDCD7 PF16021.5 CDJ80645.1 - 0.065 12.3 0.3 0.11 11.6 0.3 1.3 1 0 0 1 1 1 0 Programmed cell death protein 7 DivIC PF04977.15 CDJ80645.1 - 0.15 11.9 0.7 26 4.7 0.2 2.7 2 0 0 2 2 2 0 Septum formation initiator CorA PF01544.18 CDJ80645.1 - 0.24 10.7 2.4 0.47 9.7 2.4 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Cep57_CLD_2 PF14197.6 CDJ80645.1 - 0.4 10.8 3.7 0.3 11.2 1.1 2.1 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 EzrA PF06160.12 CDJ80645.1 - 0.53 8.4 6.3 0.12 10.5 2.9 1.6 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA AA_permease_2 PF13520.6 CDJ80646.1 - 3e-12 46.1 9.7 3.5e-12 45.9 9.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CDJ80646.1 - 2.3e-07 29.8 5.7 2.6e-07 29.6 5.7 1.0 1 0 0 1 1 1 1 Amino acid permease Trp_Tyr_perm PF03222.13 CDJ80646.1 - 0.0057 15.7 4.1 0.0064 15.6 4.1 1.1 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family DUF2207 PF09972.9 CDJ80646.1 - 0.17 10.6 0.2 0.2 10.4 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1072 PF06380.11 CDJ80646.1 - 0.28 11.1 3.4 0.61 10.0 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) Chibby PF14645.6 CDJ80649.1 - 0.035 14.5 1.0 0.07 13.5 0.2 1.9 2 0 0 2 2 2 0 Chibby family MctB PF11382.8 CDJ80649.1 - 0.53 10.0 4.4 1 9.0 4.4 1.4 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB ZapB PF06005.12 CDJ80649.1 - 0.64 10.5 14.4 0.24 11.9 9.4 2.2 2 0 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 CDJ80649.1 - 3.9 7.3 10.5 7.5 6.4 10.5 1.4 1 0 0 1 1 1 0 Septum formation initiator bZIP_Maf PF03131.17 CDJ80649.1 - 8.7 6.9 11.9 1.3 9.6 7.7 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor UNC-93 PF05978.16 CDJ80650.1 - 2e-56 190.1 12.0 2e-56 190.1 12.0 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 CDJ80650.1 - 1.2e-12 47.5 30.3 5.6e-12 45.3 23.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5336 PF17270.2 CDJ80650.1 - 0.0013 18.4 0.1 0.0046 16.6 0.1 1.9 1 0 0 1 1 1 1 Family of unknown function (DUF5336) DUF2427 PF10348.9 CDJ80650.1 - 5.1 6.9 13.5 0.83 9.5 2.2 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) Glyco_transf_43 PF03360.16 CDJ80651.1 - 1.9e-47 161.8 0.0 2.5e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 43 SpoIIM PF01944.17 CDJ80651.1 - 0.25 11.4 1.8 0.41 10.7 0.9 1.9 2 1 0 2 2 2 0 Stage II sporulation protein M Collagen PF01391.18 CDJ80652.1 - 1.3e-22 79.3 70.3 4.5e-11 42.3 26.7 2.9 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Robl_LC7 PF03259.17 CDJ80654.1 - 5.9e-23 80.5 0.1 6.7e-23 80.3 0.1 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 CDJ80654.1 - 6.5e-05 22.8 0.1 8.6e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 DUF3523 PF12037.8 CDJ80655.1 - 1.5e-93 313.1 35.8 1.5e-93 313.1 35.8 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3523) AAA PF00004.29 CDJ80655.1 - 3.8e-24 85.6 0.0 9.6e-24 84.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ80655.1 - 3.3e-05 24.3 0.0 3.3e-05 24.3 0.0 3.5 2 2 0 2 2 1 1 AAA ATPase domain AAA_33 PF13671.6 CDJ80655.1 - 6.3e-05 23.2 0.0 6.3e-05 23.2 0.0 3.2 3 1 1 4 4 2 1 AAA domain RuvB_N PF05496.12 CDJ80655.1 - 6.6e-05 22.7 0.0 0.00023 21.0 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CDJ80655.1 - 0.0022 18.0 0.1 0.059 13.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CDJ80655.1 - 0.0051 17.4 1.3 0.14 12.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CDJ80655.1 - 0.0053 16.5 0.3 0.014 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zot PF05707.12 CDJ80655.1 - 0.0065 16.1 0.3 0.31 10.7 0.1 2.9 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) Mg_chelatase PF01078.21 CDJ80655.1 - 0.0082 15.5 0.0 0.023 14.1 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CDJ80655.1 - 0.01 15.6 0.3 0.036 13.8 0.0 2.1 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_22 PF13401.6 CDJ80655.1 - 0.011 15.9 2.7 0.52 10.6 0.0 3.3 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 CDJ80655.1 - 0.017 15.5 0.0 0.039 14.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 CDJ80655.1 - 0.021 14.3 0.0 0.045 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 CDJ80655.1 - 0.026 14.5 0.1 0.098 12.7 0.0 2.0 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_lid_3 PF17862.1 CDJ80655.1 - 0.044 13.6 0.4 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA+ lid domain Sigma54_activ_2 PF14532.6 CDJ80655.1 - 0.065 13.4 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.6 CDJ80655.1 - 0.089 13.0 0.0 0.089 13.0 0.0 3.6 3 1 1 4 4 3 0 AAA domain AAA_3 PF07726.11 CDJ80655.1 - 0.11 12.3 0.6 0.4 10.6 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RecQ_Zn_bind PF16124.5 CDJ80655.1 - 0.34 11.7 1.4 1.6 9.5 0.0 2.8 2 0 0 2 2 2 0 RecQ zinc-binding AAA_11 PF13086.6 CDJ80655.1 - 0.74 9.5 0.0 0.74 9.5 0.0 3.4 2 1 1 3 3 1 0 AAA domain DUF648 PF04890.13 CDJ80655.1 - 1.2 8.8 4.9 2.1 8.0 4.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF648) AAA_25 PF13481.6 CDJ80655.1 - 1.4 8.5 6.5 0.67 9.5 0.2 3.2 3 1 0 3 3 3 0 AAA domain TFIIA PF03153.13 CDJ80655.1 - 2.5 8.0 17.1 4.2 7.3 17.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit V_ATPase_I PF01496.19 CDJ80655.1 - 8 4.2 11.7 11 3.8 11.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Yip1 PF04893.17 CDJ80656.1 - 1.1e-09 38.3 16.9 1.6e-09 37.7 16.7 1.3 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 CDJ80656.1 - 4.7e-08 32.8 8.9 2.1e-05 24.2 8.9 2.1 1 1 0 1 1 1 1 YIF1 DUF1189 PF06691.11 CDJ80656.1 - 2.4 7.7 9.6 5.4 6.5 9.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1189) ATP-synt_G PF04718.15 CDJ80657.1 - 4e-18 66.1 0.1 7.9e-18 65.1 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit tRNA_bind_3 PF17176.4 CDJ80657.1 - 0.077 13.3 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 tRNA-binding domain Tricorn_C1 PF14684.6 CDJ80657.1 - 0.11 12.5 0.4 2.5 8.2 0.1 2.2 2 0 0 2 2 2 0 Tricorn protease C1 domain WD40 PF00400.32 CDJ80658.1 - 1.9e-59 196.2 24.3 2.3e-08 34.6 0.2 9.2 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ80658.1 - 7.6e-22 77.4 3.0 5e-06 26.7 0.6 5.9 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 CDJ80658.1 - 3e-09 37.3 0.0 5.6e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 CDJ80658.1 - 1.5e-07 30.7 0.1 0.26 10.2 0.0 4.2 3 2 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 CDJ80658.1 - 0.00041 18.8 0.0 0.0016 16.8 0.0 1.9 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 CDJ80658.1 - 0.0012 17.6 1.7 1.3 7.6 0.1 4.4 3 2 1 4 4 4 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 CDJ80658.1 - 0.0066 15.0 0.0 0.085 11.4 0.0 2.4 2 1 1 3 3 3 1 Cytochrome D1 heme domain PD40 PF07676.12 CDJ80658.1 - 0.0068 16.3 0.9 2.6 8.1 0.0 4.2 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat CHAP PF05257.16 CDJ80658.1 - 0.012 16.1 0.5 0.54 10.9 0.8 3.2 3 1 0 3 3 3 0 CHAP domain WD40_like PF17005.5 CDJ80658.1 - 0.027 13.8 0.0 3.3 6.9 0.0 3.2 3 0 0 3 3 3 0 WD40-like domain TRAM_LAG1_CLN8 PF03798.16 CDJ80659.1 - 5e-20 72.1 14.0 7.4e-20 71.5 14.0 1.3 1 0 0 1 1 1 1 TLC domain Gemini_mov PF01708.16 CDJ80659.1 - 0.11 12.3 2.5 12 5.7 0.0 3.1 3 0 0 3 3 3 0 Geminivirus putative movement protein DUF3021 PF11457.8 CDJ80659.1 - 0.12 12.8 5.7 0.14 12.5 2.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3021) His_Phos_2 PF00328.22 CDJ80660.1 - 6.4e-31 108.1 0.0 3.5e-30 105.6 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) IceA2 PF05862.11 CDJ80660.1 - 0.14 12.1 0.5 0.26 11.2 0.5 1.4 1 0 0 1 1 1 0 Helicobacter pylori IceA2 protein His_Phos_2 PF00328.22 CDJ80661.1 - 1.2e-41 143.3 0.0 5.5e-41 141.2 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1759 PF03564.15 CDJ80662.1 - 7.7e-08 32.4 0.4 1.8e-07 31.2 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DRY_EERY PF09750.9 CDJ80663.1 - 0.041 14.1 2.6 0.05 13.9 2.6 1.1 1 0 0 1 1 1 0 Alternative splicing regulator DUF592 PF04574.13 CDJ80663.1 - 0.1 12.4 0.2 0.11 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF592) His_Phos_2 PF00328.22 CDJ80664.1 - 3e-26 92.7 0.1 3.4e-26 92.5 0.1 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TraH_2 PF06871.11 CDJ80664.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 TraH_2 BRCT_assoc PF12820.7 CDJ80664.1 - 0.18 11.6 0.1 0.28 11.0 0.1 1.3 1 0 0 1 1 1 0 Serine-rich domain associated with BRCT His_Phos_2 PF00328.22 CDJ80665.1 - 1e-47 163.3 0.0 3e-47 161.8 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DNA_ligase_A_M PF01068.21 CDJ80666.1 - 3e-65 219.7 0.0 5.5e-65 218.8 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CDJ80666.1 - 3.4e-42 144.7 0.0 5.7e-42 144.0 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 CDJ80666.1 - 7.2e-24 84.3 0.0 1.4e-23 83.3 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.19 CDJ80666.1 - 0.00029 20.7 0.0 0.056 13.3 0.0 2.5 2 0 0 2 2 2 2 mRNA capping enzyme, catalytic domain DNA_ligase_OB_2 PF14743.6 CDJ80666.1 - 0.021 14.8 0.2 6.1 6.9 0.1 2.8 3 0 0 3 3 3 0 DNA ligase OB-like domain Collagen PF01391.18 CDJ80667.1 - 2.5e-20 72.0 136.8 9.5e-08 31.7 39.3 4.1 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Glyco_hydro_56 PF01630.18 CDJ80668.1 - 5.3e-98 328.1 0.5 6.5e-98 327.8 0.5 1.0 1 0 0 1 1 1 1 Hyaluronidase SR-25 PF10500.9 CDJ80669.1 - 0.0085 15.7 20.8 0.01 15.5 20.8 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Zip PF02535.22 CDJ80669.1 - 0.021 14.1 0.6 0.021 14.0 0.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CCDC106 PF15794.5 CDJ80669.1 - 0.025 14.3 10.6 0.036 13.8 10.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF4674 PF15719.5 CDJ80669.1 - 0.049 13.7 18.7 0.017 15.2 16.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4674) Connexin PF00029.19 CDJ80669.1 - 0.081 12.7 0.7 0.091 12.5 0.7 1.2 1 0 0 1 1 1 0 Connexin MAP17 PF15807.5 CDJ80669.1 - 0.092 13.0 2.6 0.13 12.5 2.6 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Serinc PF03348.15 CDJ80669.1 - 0.13 11.2 0.2 0.16 10.9 0.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) SID-1_RNA_chan PF13965.6 CDJ80669.1 - 0.19 10.1 0.2 0.21 10.0 0.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 OATP PF03137.20 CDJ80669.1 - 0.28 9.4 0.4 0.34 9.1 0.4 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Macoilin PF09726.9 CDJ80669.1 - 0.41 9.2 10.9 0.43 9.1 10.9 1.0 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 CDJ80669.1 - 0.75 8.5 5.7 0.8 8.4 5.7 1.2 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 CDJ80669.1 - 0.76 8.7 4.9 0.77 8.7 4.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 CDJ80669.1 - 0.89 9.3 12.1 1 9.1 12.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PPL5 PF18168.1 CDJ80669.1 - 1.2 8.4 5.6 1.3 8.3 5.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DUF3807 PF12720.7 CDJ80669.1 - 1.4 9.2 11.9 1.6 8.9 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) FancD2 PF14631.6 CDJ80669.1 - 1.6 6.0 7.5 1.8 5.9 7.5 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease CDC45 PF02724.14 CDJ80669.1 - 3 6.0 7.6 3 6.0 7.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.8 CDJ80669.1 - 3.3 6.4 14.0 3.9 6.1 14.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF1180 PF06679.12 CDJ80669.1 - 3.5 8.0 8.6 1.7 9.1 6.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) FAM176 PF14851.6 CDJ80669.1 - 5.1 6.8 6.7 15 5.2 6.7 1.8 1 1 0 1 1 1 0 FAM176 family NARP1 PF12569.8 CDJ80669.1 - 6.6 5.5 13.1 7.3 5.4 13.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Motile_Sperm PF00635.26 CDJ80670.1 - 6.1e-23 80.8 0.1 1e-22 80.0 0.1 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain HAD_2 PF13419.6 CDJ80671.1 - 8.2e-23 81.4 0.0 9.5e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDJ80671.1 - 3.4e-13 50.4 0.0 2.2e-12 47.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CDJ80671.1 - 0.00019 21.9 0.0 0.00033 21.1 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CDJ80671.1 - 0.0021 18.2 0.0 0.053 13.6 0.0 2.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NT5C PF06941.12 CDJ80671.1 - 0.0041 17.0 0.0 0.0071 16.2 0.0 1.4 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Hydrolase_like PF13242.6 CDJ80671.1 - 0.0086 16.1 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like zf-C2HC_2 PF13913.6 CDJ80671.1 - 0.43 10.5 2.3 4.3 7.3 0.1 2.9 2 1 1 3 3 3 0 zinc-finger of a C2HC-type Adeno_E3_CR2 PF02439.15 CDJ80672.1 - 0.031 14.0 3.9 0.066 13.0 3.9 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF5367 PF17329.2 CDJ80672.1 - 0.032 14.4 0.3 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5367) MAP17 PF15807.5 CDJ80672.1 - 0.06 13.6 0.0 0.06 13.6 0.0 2.2 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4834 PF16118.5 CDJ80672.1 - 0.087 13.8 0.1 0.087 13.8 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) MCLC PF05934.11 CDJ80672.1 - 0.16 10.7 5.0 0.28 9.9 5.0 1.4 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Syndecan PF01034.20 CDJ80672.1 - 0.44 10.5 3.3 0.95 9.4 3.3 1.4 1 0 0 1 1 1 0 Syndecan domain DUF4064 PF13273.6 CDJ80672.1 - 0.75 10.1 7.7 3.7 7.9 7.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Phage_tube PF04985.14 CDJ80672.1 - 1 9.1 5.5 2 8.1 5.5 1.4 1 0 0 1 1 1 0 Phage tail tube protein FII EF-hand_6 PF13405.6 CDJ80673.1 - 0.0002 21.0 3.0 0.0052 16.6 0.1 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 CDJ80673.1 - 0.00023 20.5 4.0 0.00026 20.3 0.3 2.9 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.6 CDJ80673.1 - 0.00044 20.6 0.2 0.00044 20.6 0.2 2.6 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_8 PF13833.6 CDJ80673.1 - 0.001 18.9 0.5 0.0029 17.4 0.1 2.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 CDJ80673.1 - 0.026 14.0 0.4 0.026 14.0 0.4 2.1 2 0 0 2 2 2 0 EF hand Suv3_N PF18114.1 CDJ80673.1 - 0.055 13.6 0.0 1.5 9.0 0.0 2.7 2 1 1 3 3 3 0 Suv3 helical N-terminal domain DUF1011 PF06237.12 CDJ80674.1 - 0.0012 19.2 0.9 0.0012 19.2 0.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1011) RVT_1 PF00078.27 CDJ80675.1 - 2.7e-07 30.3 0.0 6.2e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Collagen PF01391.18 CDJ80676.1 - 6.9e-27 93.0 93.5 4.8e-10 39.0 32.2 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ80676.1 - 2.4e-10 40.3 0.3 4e-10 39.6 0.3 1.4 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain FNIP_M PF14637.6 CDJ80676.1 - 0.056 13.4 0.0 0.076 13.0 0.0 1.0 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain FAM76 PF16046.5 CDJ80679.1 - 1.1e-35 123.4 41.7 7.2e-25 88.0 25.2 2.0 1 1 1 2 2 2 2 FAM76 protein DUF2009 PF09418.10 CDJ80679.1 - 0.00073 18.7 1.2 0.0011 18.2 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) FliJ PF02050.16 CDJ80679.1 - 0.094 12.9 9.3 0.16 12.2 9.3 1.4 1 0 0 1 1 1 0 Flagellar FliJ protein XLF PF09302.11 CDJ80679.1 - 1.1 9.4 8.2 10 6.3 2.9 2.4 1 1 1 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component CENP-H PF05837.12 CDJ80679.1 - 4.6 7.7 11.5 0.34 11.3 6.1 1.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Collagen PF01391.18 CDJ80680.1 - 2e-23 81.9 89.2 3.4e-10 39.5 31.4 3.9 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) UMPH-1 PF05822.12 CDJ80681.1 - 2.7e-89 298.9 1.0 3.5e-89 298.6 1.0 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 CDJ80681.1 - 7.3e-07 29.8 0.0 1.2e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase TPP1 PF10341.9 CDJ80681.1 - 0.027 14.4 0.1 0.066 13.2 0.1 1.6 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD UMPH-1 PF05822.12 CDJ80682.1 - 8.9e-37 126.9 0.0 1.2e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 CDJ80682.1 - 2.8e-06 27.8 0.0 6.4e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Bestrophin PF01062.21 CDJ80683.1 - 1.4e-84 284.0 9.9 2e-84 283.5 9.9 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel zf-CCCH PF00642.24 CDJ80683.1 - 1.6e-09 37.4 14.6 6.6e-05 22.7 2.0 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CDJ80683.1 - 8.1e-07 29.7 3.0 0.0096 16.6 0.2 2.6 2 0 0 2 2 2 2 Torus domain RRM_1 PF00076.22 CDJ80683.1 - 1.1e-05 25.1 0.1 2.8e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 CDJ80683.1 - 0.00071 19.5 19.6 0.025 14.6 4.7 2.9 3 0 0 3 3 3 2 Zinc finger domain TLE_N PF03920.15 CDJ80683.1 - 0.052 13.6 0.4 0.13 12.4 0.4 1.6 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain zf-CCCH_3 PF15663.5 CDJ80683.1 - 1.3 9.2 4.5 11 6.3 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger containing family Keratin_2_head PF16208.5 CDJ80683.1 - 1.4 9.1 18.8 5 7.2 10.3 2.3 2 0 0 2 2 2 0 Keratin type II head ERAP1_C PF11838.8 CDJ80684.1 - 2.4e-51 175.2 0.6 2.9e-51 174.9 0.6 1.0 1 0 0 1 1 1 1 ERAP1-like C-terminal domain HTH_Tnp_Tc3_1 PF11427.8 CDJ80684.1 - 0.055 13.3 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Tc3 transposase MFS_1 PF07690.16 CDJ80685.1 - 1.7e-29 102.9 32.5 8e-18 64.5 4.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CDJ80685.1 - 2.7e-12 46.0 25.2 7e-11 41.3 17.9 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein FA_desaturase PF00487.24 CDJ80685.1 - 0.061 13.2 1.8 0.11 12.3 1.8 1.7 1 0 0 1 1 1 0 Fatty acid desaturase UDPGT PF00201.18 CDJ80686.1 - 3.8e-07 29.3 0.0 4e-07 29.2 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_4 PF13439.6 CDJ80686.1 - 8.8e-06 25.8 0.1 4e-05 23.7 0.1 1.8 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 CDJ80686.1 - 0.0041 17.6 0.0 0.0063 17.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 CDJ80686.1 - 0.055 13.5 0.2 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase 4-like DUF16 PF01519.16 CDJ80686.1 - 0.092 13.2 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 TTR-52 PF01060.23 CDJ80687.1 - 2.6e-22 79.3 0.0 3.4e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Transthyretin-like family bMG3 PF11974.8 CDJ80687.1 - 0.027 14.5 0.0 0.038 14.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain Transthyretin PF00576.21 CDJ80687.1 - 0.17 12.6 0.0 0.26 12.0 0.0 1.3 1 0 0 1 1 1 0 HIUase/Transthyretin family Baculo_p24 PF05073.12 CDJ80688.1 - 0.0011 18.8 2.0 0.0018 18.1 2.0 1.3 1 0 0 1 1 1 1 Baculovirus P24 capsid protein Phage_int_SAM_6 PF18644.1 CDJ80688.1 - 0.0082 16.2 0.6 0.01 15.9 0.6 1.2 1 0 0 1 1 1 1 Phage integrase SAM-like domain Apolipoprotein PF01442.18 CDJ80688.1 - 0.011 15.7 0.3 0.012 15.5 0.3 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain PhaP_Bmeg PF09602.10 CDJ80688.1 - 0.018 15.0 3.6 0.021 14.7 3.6 1.1 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF1664 PF07889.12 CDJ80688.1 - 0.025 14.6 1.5 0.047 13.7 1.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Rab5-bind PF09311.11 CDJ80688.1 - 0.031 13.7 3.4 0.036 13.4 3.4 1.1 1 0 0 1 1 1 0 Rabaptin-like protein DUF4201 PF13870.6 CDJ80688.1 - 0.042 13.6 6.5 0.24 11.1 1.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Exonuc_VII_L PF02601.15 CDJ80688.1 - 0.043 13.4 0.8 0.051 13.1 0.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF948 PF06103.11 CDJ80688.1 - 0.054 13.8 2.5 0.17 12.1 2.5 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF4735 PF15882.5 CDJ80688.1 - 0.066 12.7 0.4 0.079 12.4 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) LPD11 PF18824.1 CDJ80688.1 - 0.09 12.9 0.2 0.18 11.9 0.0 1.7 2 1 0 2 2 2 0 Large polyvalent protein-associated domain 11 Flt3_lig PF02947.14 CDJ80688.1 - 0.097 12.9 0.3 0.13 12.5 0.3 1.3 1 0 0 1 1 1 0 flt3 ligand DUF2203 PF09969.9 CDJ80688.1 - 0.099 13.4 1.6 0.16 12.7 1.6 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Uso1_p115_C PF04871.13 CDJ80688.1 - 0.31 11.4 3.9 0.43 11.0 3.9 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Muted PF14942.6 CDJ80688.1 - 0.88 9.9 6.4 1.8 8.9 6.5 1.5 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein RdRP PF05183.12 CDJ80689.1 - 5.1e-156 520.7 0.0 6.5e-156 520.4 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Nrap_D2 PF17403.2 CDJ80689.1 - 0.13 12.1 0.0 11 5.8 0.0 2.5 2 0 0 2 2 2 0 Nrap protein PAP/OAS-like domain POT1PC PF16686.5 CDJ80690.1 - 3.6e-10 39.9 0.0 1.5e-09 37.9 0.0 1.9 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 CDJ80690.1 - 2.8e-08 33.7 0.0 1.8e-07 31.1 0.0 2.4 2 1 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.25 CDJ80690.1 - 0.0023 17.9 0.1 0.29 11.1 0.0 2.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Hormone_recep PF00104.30 CDJ80691.1 - 8.7e-29 100.6 0.0 1.6e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 CDJ80691.1 - 2.5e-28 98.3 19.1 2.5e-28 98.3 19.1 2.1 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Pkinase PF00069.25 CDJ80693.1 - 1e-62 211.9 0.0 1.6e-62 211.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ80693.1 - 5.6e-39 134.0 0.0 8.8e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 CDJ80693.1 - 1.1e-29 102.1 34.8 6.4e-16 58.0 9.2 2.9 3 0 0 3 3 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 CDJ80693.1 - 2.6e-10 40.8 0.8 5.2e-10 39.9 0.8 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CDJ80693.1 - 8.4e-06 25.0 0.5 1.3e-05 24.3 0.5 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Zf_RING PF16744.5 CDJ80693.1 - 0.0021 18.1 12.2 0.034 14.2 1.9 2.6 2 0 0 2 2 2 2 KIAA1045 RING finger Kinase-like PF14531.6 CDJ80693.1 - 0.0033 16.8 0.0 0.0071 15.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDJ80693.1 - 0.0069 15.8 0.1 0.011 15.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Act-Frag_cataly PF09192.10 CDJ80693.1 - 0.016 14.6 0.7 0.027 13.9 0.7 1.2 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic FTA2 PF13095.6 CDJ80693.1 - 0.033 13.8 0.8 3 7.4 0.1 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CDJ80693.1 - 0.06 13.3 0.1 1 9.2 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family PHD PF00628.29 CDJ80693.1 - 0.5 10.3 23.1 0.14 12.1 5.4 2.8 2 0 0 2 2 2 0 PHD-finger C1_2 PF03107.16 CDJ80693.1 - 4.3 7.7 28.3 0.47 10.8 3.6 3.0 3 0 0 3 3 2 0 C1 domain Cyclin_N PF00134.23 CDJ80695.1 - 1.8e-28 98.8 0.6 5.1e-28 97.4 0.3 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain HA70_C PF17993.1 CDJ80695.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Haemagglutinin 70 C-terminal domain IL4Ra_N PF09238.10 CDJ80696.1 - 0.046 14.1 0.2 0.078 13.3 0.0 1.4 2 0 0 2 2 2 0 Interleukin-4 receptor alpha chain, N-terminal DUF1690 PF07956.11 CDJ80696.1 - 0.055 13.9 0.8 0.065 13.7 0.8 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) tRNA-synt_2c PF01411.19 CDJ80697.1 - 6.7e-165 549.7 0.0 8.2e-165 549.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CDJ80697.1 - 5.3e-09 36.0 0.0 2.8e-08 33.7 0.1 2.3 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain CRAL_TRIO_2 PF13716.6 CDJ80698.1 - 5.5e-42 143.2 1.3 2.1e-41 141.3 0.4 2.1 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 CDJ80698.1 - 7e-38 129.8 0.2 2e-37 128.4 0.1 1.7 2 0 0 2 2 2 1 RhoGAP domain CRAL_TRIO PF00650.20 CDJ80698.1 - 3.8e-09 36.5 0.5 3.8e-09 36.5 0.5 1.8 2 1 0 2 2 2 1 CRAL/TRIO domain zf-CDGSH PF09360.10 CDJ80699.1 - 1.4e-10 41.2 1.1 6.4e-10 39.1 0.1 2.2 2 0 0 2 2 2 1 Iron-binding zinc finger CDGSH type Methyltransf_4 PF02390.17 CDJ80700.1 - 7.1e-58 194.9 0.0 1.1e-57 194.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Mito_carr PF00153.27 CDJ80700.1 - 5.2e-56 186.6 0.6 1.4e-17 63.4 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_25 PF13649.6 CDJ80700.1 - 0.0062 17.2 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ80700.1 - 0.034 14.9 0.0 0.14 12.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Lar_restr_allev PF14354.6 CDJ80700.1 - 0.054 13.9 0.8 0.054 13.9 0.8 2.0 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-RRN7 PF11781.8 CDJ80700.1 - 0.058 13.1 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Methyltransf_31 PF13847.6 CDJ80700.1 - 0.065 13.0 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MCR_gamma PF02240.16 CDJ80700.1 - 0.16 11.2 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 Methyl-coenzyme M reductase gamma subunit zf-nanos PF05741.13 CDJ80701.1 - 6.8e-19 67.9 2.2 1.2e-18 67.0 2.2 1.5 1 0 0 1 1 1 1 Nanos RNA binding domain HypA PF01155.19 CDJ80701.1 - 0.058 13.4 4.3 2.6 8.1 0.7 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-CCHC_6 PF15288.6 CDJ80701.1 - 0.14 12.0 0.4 0.9 9.4 0.4 2.5 1 0 0 1 1 1 0 Zinc knuckle SAGA-Tad1 PF12767.7 CDJ80701.1 - 0.15 11.8 4.6 0.29 10.8 4.6 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF4083 PF13314.6 CDJ80703.1 - 0.23 11.4 2.8 0.53 10.3 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) CEBP_ZZ PF16366.5 CDJ80704.1 - 4.1e-17 62.2 6.8 1.1e-16 60.7 6.8 1.8 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_7 PF16367.5 CDJ80704.1 - 3.6e-16 59.1 0.1 6.5e-13 48.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif RRM_1 PF00076.22 CDJ80704.1 - 1.5e-15 56.8 0.0 6.3e-07 29.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-B_box PF00643.24 CDJ80704.1 - 0.64 10.2 8.4 1.6 8.9 8.4 1.7 1 0 0 1 1 1 0 B-box zinc finger AAA_11 PF13086.6 CDJ80705.1 - 2.3e-05 24.3 0.0 2.8e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 CDJ80705.1 - 8.9e-05 22.2 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain HTH_1 PF00126.27 CDJ80705.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Pribosyltran PF00156.27 CDJ80706.1 - 9e-22 77.3 0.0 1.2e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CDJ80706.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase RIO1 PF01163.22 CDJ80707.1 - 2.6e-47 160.9 0.0 4.5e-47 160.1 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 CDJ80707.1 - 1.6e-29 102.0 0.0 3.5e-29 100.8 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 CDJ80707.1 - 4.6e-10 39.8 8.9 0.00018 21.5 0.1 3.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 CDJ80707.1 - 1.4e-07 31.1 0.6 0.0029 17.0 0.0 2.6 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 CDJ80707.1 - 0.095 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 HTH_IclR PF09339.10 CDJ80707.1 - 0.14 12.0 0.1 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain RRN3 PF05327.11 CDJ80707.1 - 3.5 6.0 9.0 5.1 5.5 9.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 CDJ80707.1 - 4 6.8 16.2 6.6 6.0 16.2 1.3 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 CDJ80707.1 - 7.1 4.6 13.5 9.9 4.1 13.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi BTB PF00651.31 CDJ80708.1 - 2.6e-20 72.7 4.9 1.3e-19 70.5 0.2 2.7 2 1 1 3 3 3 1 BTB/POZ domain CAMSAP_CH PF11971.8 CDJ80708.1 - 0.023 14.5 0.1 0.078 12.8 0.1 1.9 1 0 0 1 1 1 0 CAMSAP CH domain BACK PF07707.15 CDJ80708.1 - 0.056 13.5 0.3 0.62 10.2 0.1 2.3 2 0 0 2 2 2 0 BTB And C-terminal Kelch DUF5487 PF17589.2 CDJ80708.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5487) Caveolin PF01146.17 CDJ80709.1 - 2.2e-38 131.2 1.0 3e-38 130.8 1.0 1.2 1 0 0 1 1 1 1 Caveolin G-alpha PF00503.20 CDJ80710.1 - 1.7e-114 382.7 10.1 2e-114 382.5 10.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDJ80710.1 - 8e-14 51.5 1.6 7.6e-10 38.5 0.2 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ80710.1 - 0.0001 21.8 3.1 0.079 12.3 0.5 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 CDJ80710.1 - 0.00078 19.7 7.4 0.37 11.0 0.9 3.2 1 1 2 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 CDJ80710.1 - 0.0018 17.7 0.3 0.0042 16.5 0.1 1.7 2 0 0 2 2 2 1 Bacterial TniB protein AAA_29 PF13555.6 CDJ80710.1 - 0.035 13.8 0.2 0.29 10.9 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 CDJ80710.1 - 0.066 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Spectrin PF00435.21 CDJ80711.1 - 5.1e-263 852.9 172.2 7e-20 71.5 4.8 17.4 17 0 0 17 17 17 17 Spectrin repeat CH PF00307.31 CDJ80711.1 - 1.3e-46 157.3 12.5 3e-26 91.7 0.1 4.8 6 0 0 6 6 6 2 Calponin homology (CH) domain PH_9 PF15410.6 CDJ80711.1 - 1.1e-13 51.6 0.2 1.2e-12 48.2 0.1 2.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 CDJ80711.1 - 3.1e-10 40.5 4.1 3.6e-10 40.3 0.0 2.9 3 0 0 3 3 3 1 PH domain CAMSAP_CH PF11971.8 CDJ80711.1 - 1.1e-08 34.8 0.3 2.6e-06 27.2 0.1 2.7 2 0 0 2 2 2 1 CAMSAP CH domain CH_2 PF06294.11 CDJ80711.1 - 0.029 14.5 0.8 1.7 8.8 0.0 4.1 3 0 0 3 3 3 0 CH-like domain in sperm protein DUF5616 PF18481.1 CDJ80711.1 - 0.041 14.2 1.0 6.5 7.1 0.0 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5616) PH_11 PF15413.6 CDJ80711.1 - 0.48 10.9 3.1 0.94 9.9 0.1 3.3 3 0 0 3 3 3 0 Pleckstrin homology domain BLOC1_2 PF10046.9 CDJ80711.1 - 0.94 9.8 0.0 0.94 9.8 0.0 9.2 11 1 2 13 13 13 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 JAMP PF05571.12 CDJ80712.1 - 3.2e-30 105.8 7.4 3.2e-30 105.8 7.4 1.8 2 0 0 2 2 2 1 JNK1/MAPK8-associated membrane protein Seipin PF06775.14 CDJ80712.1 - 1.2e-25 90.8 2.7 2.4e-25 89.8 2.7 1.5 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Ninjurin PF04923.12 CDJ80712.1 - 0.0085 16.0 2.2 0.047 13.6 0.2 2.3 2 0 0 2 2 2 1 Ninjurin CDP-OH_P_transf PF01066.21 CDJ80713.1 - 3.1e-12 47.1 0.1 3.1e-12 47.1 0.1 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase adh_short_C2 PF13561.6 CDJ80714.1 - 6.5e-59 199.3 1.3 7.6e-59 199.1 1.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDJ80714.1 - 1.2e-49 168.5 1.7 1.5e-49 168.2 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDJ80714.1 - 4.4e-09 36.5 0.2 6.1e-09 36.0 0.2 1.1 1 0 0 1 1 1 1 KR domain MtrA PF04208.14 CDJ80714.1 - 0.022 14.4 0.5 0.059 13.0 0.1 1.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit A 2-Hacid_dh_C PF02826.19 CDJ80714.1 - 0.053 12.9 0.2 0.08 12.3 0.2 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Helicase_RecD PF05127.14 CDJ80714.1 - 0.15 11.9 0.3 4.7 7.0 0.0 2.1 2 0 0 2 2 2 0 Helicase KCNQ2_u3 PF16642.5 CDJ80715.1 - 0.29 12.1 5.8 0.14 13.2 1.7 2.1 1 1 1 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 Myosin_head PF00063.21 CDJ80716.1 - 1.6e-102 343.9 0.1 2.3e-102 343.4 0.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.17 CDJ80716.1 - 1.9e-44 150.6 4.1 1.4e-27 96.3 0.1 3.4 3 0 0 3 3 3 2 MyTH4 domain FERM_M PF00373.18 CDJ80716.1 - 5.9e-08 33.1 0.0 6.5e-07 29.8 0.0 2.9 3 0 0 3 3 3 1 FERM central domain SH3_9 PF14604.6 CDJ80716.1 - 1e-06 28.5 0.0 2.7e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CDJ80716.1 - 2.6e-06 27.0 0.0 1.1e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain IQ PF00612.27 CDJ80716.1 - 3e-06 26.5 7.6 0.0029 17.3 1.0 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif SH3_1 PF00018.28 CDJ80716.1 - 0.024 14.2 0.0 0.056 13.1 0.0 1.6 1 0 0 1 1 1 0 SH3 domain PA26 PF04636.13 CDJ80719.1 - 2.3 7.0 10.8 3.3 6.5 10.8 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) HSP20 PF00011.21 CDJ80720.1 - 6e-22 77.7 0.1 7.7e-22 77.4 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ80720.1 - 0.012 15.1 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 HSP20-like domain found in ArsA Na_sulph_symp PF00939.19 CDJ80723.1 - 2.3e-16 59.9 3.4 2.4e-16 59.8 3.4 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CDJ80723.1 - 2.4e-08 33.6 11.2 7.6e-08 31.9 11.2 1.7 1 1 0 1 1 1 1 Citrate transporter Pkinase PF00069.25 CDJ80724.1 - 4.4e-05 23.0 0.0 5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Bromo_TP PF07524.13 CDJ80725.1 - 0.058 13.4 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Bromodomain associated VPS28 PF03997.12 CDJ80725.1 - 0.11 12.2 2.7 0.21 11.2 0.0 2.5 3 1 0 3 3 3 0 VPS28 protein DUF2431 PF10354.9 CDJ80727.1 - 1.8e-33 116.2 0.0 1.2e-32 113.5 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF2431) Ras PF00071.22 CDJ80727.1 - 3e-25 88.7 0.1 4.9e-25 88.0 0.1 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ80727.1 - 4.8e-07 30.0 0.0 1.2e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Methyltransf_4 PF02390.17 CDJ80727.1 - 0.0091 15.5 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Arf PF00025.21 CDJ80727.1 - 0.057 12.9 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Ras PF00071.22 CDJ80729.1 - 2.5e-26 92.2 0.2 5.2e-26 91.2 0.2 1.6 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ80729.1 - 3.8e-20 72.3 0.1 3.8e-20 72.3 0.1 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GYF PF02213.16 CDJ80729.1 - 1.6e-06 27.6 0.0 4.9e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 GYF domain Arf PF00025.21 CDJ80729.1 - 1.3e-05 24.7 0.0 3.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ80729.1 - 0.0015 18.6 0.0 0.005 16.9 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDJ80729.1 - 0.0018 17.7 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 CDJ80729.1 - 0.0077 16.6 0.1 0.03 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain DUF5616 PF18481.1 CDJ80729.1 - 0.021 15.1 0.1 0.087 13.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5616) AAA_29 PF13555.6 CDJ80729.1 - 0.031 14.0 0.0 0.096 12.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CDJ80729.1 - 0.052 13.5 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 CDJ80729.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDJ80729.1 - 0.13 11.8 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 CDJ80729.1 - 0.27 11.7 2.1 0.55 10.8 0.0 2.4 2 1 0 2 2 2 0 ABC transporter AAA_21 PF13304.6 CDJ80729.1 - 6 6.6 8.5 1.2 8.8 0.1 2.4 2 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Fucokinase PF07959.12 CDJ80731.1 - 1.5e-26 93.3 0.0 1.7e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 L-fucokinase HA2 PF04408.23 CDJ80732.1 - 7.7e-23 80.8 0.0 7.7e-23 80.8 0.0 4.3 6 1 1 7 7 5 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDJ80732.1 - 3.8e-16 59.2 0.0 9e-16 58.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDJ80732.1 - 8.2e-12 45.4 0.0 2e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ80732.1 - 1e-06 28.6 0.0 2.7e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 CDJ80732.1 - 0.00063 19.5 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDJ80732.1 - 0.00077 19.8 0.0 0.0026 18.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CDJ80732.1 - 0.0045 17.0 0.3 3.5 7.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.22 CDJ80732.1 - 0.0078 15.9 0.1 0.016 14.8 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 CDJ80732.1 - 0.011 16.1 0.0 0.03 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CDJ80732.1 - 0.017 14.6 0.0 0.052 13.0 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 CDJ80732.1 - 0.02 14.0 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein F-box-like PF12937.7 CDJ80732.1 - 0.029 14.2 0.0 0.22 11.4 0.1 2.3 2 0 0 2 2 2 0 F-box-like AAA_24 PF13479.6 CDJ80732.1 - 0.033 13.9 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Microtub_bd PF16796.5 CDJ80732.1 - 0.042 13.8 0.1 0.18 11.7 0.1 2.1 2 0 0 2 2 2 0 Microtubule binding Flavi_DEAD PF07652.14 CDJ80732.1 - 0.057 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain ATPase PF06745.13 CDJ80732.1 - 0.06 12.7 1.3 0.07 12.5 0.1 1.7 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 CDJ80732.1 - 0.13 11.8 0.3 0.44 10.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 CDJ80732.1 - 0.15 12.6 0.1 0.15 12.6 0.1 4.2 3 1 1 4 4 3 0 AAA domain ABC_tran PF00005.27 CDJ80732.1 - 0.3 11.6 0.0 0.3 11.6 0.0 2.3 3 0 0 3 3 2 0 ABC transporter TB2_DP1_HVA22 PF03134.19 CDJ80733.1 - 2.6e-25 88.2 11.5 3.5e-25 87.7 11.5 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family TFB6 PF17110.5 CDJ80733.1 - 0.026 14.3 0.8 0.041 13.6 0.8 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF2306 PF10067.9 CDJ80733.1 - 0.16 12.1 1.9 0.4 10.9 1.6 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) Mg_trans_NIPA PF05653.14 CDJ80734.1 - 4.6e-123 410.0 21.5 5.4e-123 409.8 21.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CDJ80734.1 - 4.6e-07 30.1 3.3 4.6e-07 30.1 3.3 3.9 3 1 0 3 3 3 1 EamA-like transporter family Anophelin PF10731.9 CDJ80734.1 - 0.17 11.8 1.9 0.5 10.2 1.9 1.7 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito Tubulin PF00091.25 CDJ80735.1 - 2.1e-63 214.1 0.1 3.5e-63 213.4 0.1 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDJ80735.1 - 8.7e-26 90.6 0.2 2e-25 89.4 0.2 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 CDJ80735.1 - 0.039 13.1 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Misat_Tub_SegII PF10644.9 CDJ80735.1 - 0.082 13.2 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CDJ80735.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain RNA_pol_L_2 PF13656.6 CDJ80736.1 - 7.8e-23 80.0 0.1 1.1e-22 79.6 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CDJ80736.1 - 2.3e-08 33.3 0.0 3.2e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain UQ_con PF00179.26 CDJ80737.1 - 3.2e-50 169.4 0.0 3.7e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CDJ80737.1 - 0.056 13.7 0.0 0.068 13.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain Syntaxin PF00804.25 CDJ80738.1 - 8.3e-64 215.0 9.6 8.3e-64 215.0 9.6 1.8 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 CDJ80738.1 - 4.4e-19 68.2 10.1 6e-19 67.8 6.0 3.1 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 CDJ80738.1 - 3.2e-11 43.5 0.9 3.2e-11 43.5 0.9 2.7 2 1 0 2 2 2 1 Syntaxin-like protein Synaptobrevin PF00957.21 CDJ80738.1 - 0.0037 17.0 4.8 0.0037 17.0 4.8 2.2 3 0 0 3 3 2 1 Synaptobrevin Syntaxin-6_N PF09177.11 CDJ80738.1 - 0.013 16.0 4.6 0.024 15.2 0.4 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Sigma_reg_N PF13800.6 CDJ80738.1 - 0.016 15.5 1.4 0.041 14.2 1.4 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal ODV-E18 PF10717.9 CDJ80738.1 - 0.043 13.7 0.5 0.092 12.6 0.5 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Lzipper-MIP1 PF14389.6 CDJ80738.1 - 0.069 13.4 0.1 0.71 10.2 0.0 2.3 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Sec34 PF04136.15 CDJ80738.1 - 0.071 13.0 2.6 3.8 7.4 0.3 2.7 2 0 0 2 2 2 0 Sec34-like family LRRC37AB_C PF14914.6 CDJ80738.1 - 0.071 13.0 2.6 0.16 11.8 2.6 1.6 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DUF2508 PF10704.9 CDJ80738.1 - 0.076 13.2 1.3 1.4 9.1 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) ABC2_membrane_3 PF12698.7 CDJ80738.1 - 0.13 11.4 0.2 0.27 10.3 0.2 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein Lge1 PF11488.8 CDJ80738.1 - 0.15 12.3 1.6 0.87 9.8 0.2 2.6 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 ETRAMP PF09716.10 CDJ80738.1 - 0.2 11.7 5.6 0.042 13.9 1.0 2.3 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) LMBR1 PF04791.16 CDJ80738.1 - 0.24 10.3 8.4 0.48 9.3 8.4 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein T2SSF PF00482.23 CDJ80738.1 - 0.24 11.3 3.7 0.6 10.1 2.8 2.0 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF2207 PF09972.9 CDJ80738.1 - 0.32 9.7 3.8 0.9 8.2 3.8 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) MCPsignal PF00015.21 CDJ80738.1 - 0.32 10.8 8.1 0.5 10.2 0.4 3.1 2 2 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Baculo_11_kDa PF06143.11 CDJ80738.1 - 0.37 10.4 3.1 1 9.0 3.1 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family Anoctamin PF04547.12 CDJ80738.1 - 0.41 9.4 2.2 0.36 9.6 0.4 1.6 1 1 1 2 2 2 0 Calcium-activated chloride channel Pox_EPC_I2-L1 PF12575.8 CDJ80738.1 - 0.45 10.8 2.1 2.1 8.7 1.1 2.4 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 DUF3139 PF11337.8 CDJ80738.1 - 0.45 11.2 3.6 1.3 9.7 3.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) Dna2 PF08696.11 CDJ80738.1 - 0.46 10.3 5.7 0.5 10.1 0.6 2.6 1 1 2 3 3 3 0 DNA replication factor Dna2 Herpes_US9 PF06072.11 CDJ80738.1 - 1 9.3 6.9 0.27 11.1 0.6 2.8 3 0 0 3 3 2 0 Alphaherpesvirus tegument protein US9 COG5 PF10392.9 CDJ80738.1 - 1.1 9.5 5.0 15 5.8 0.3 2.5 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF148 PF02520.17 CDJ80738.1 - 1.1 9.4 6.5 0.36 10.9 1.5 2.6 3 0 0 3 3 2 0 Domain of unknown function DUF148 DUF948 PF06103.11 CDJ80738.1 - 1.2 9.4 11.1 1.3 9.3 0.3 3.5 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF745 PF05335.13 CDJ80738.1 - 1.4 8.6 8.0 2.3 7.9 1.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF745) UPF0258 PF06789.12 CDJ80738.1 - 1.6 8.8 7.0 3.4 7.8 7.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) DUF2205 PF10224.9 CDJ80738.1 - 1.8 8.6 7.5 0.21 11.6 0.3 2.9 3 1 0 3 3 2 0 Short coiled-coil protein YtxH PF12732.7 CDJ80738.1 - 2 9.0 5.0 6.5 7.4 0.2 3.1 2 2 0 2 2 2 0 YtxH-like protein YabA PF06156.13 CDJ80738.1 - 2.1 9.0 7.3 8.1 7.1 0.4 3.0 2 1 1 3 3 3 0 Initiation control protein YabA Vpu PF00558.19 CDJ80738.1 - 2.8 7.8 7.0 0.51 10.1 1.8 2.5 3 0 0 3 3 3 0 Vpu protein Fib_alpha PF08702.10 CDJ80738.1 - 3.8 7.7 10.1 5.5 7.2 2.6 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Occludin_ELL PF07303.13 CDJ80738.1 - 3.9 8.3 8.5 3 8.6 0.9 2.9 3 0 0 3 3 2 0 Occludin homology domain Fez1 PF06818.15 CDJ80738.1 - 4.8 7.6 11.8 0.93 9.9 0.3 2.8 2 1 0 2 2 2 0 Fez1 ERp29 PF07749.12 CDJ80738.1 - 6.5 7.7 8.6 0.34 11.8 0.5 2.9 3 1 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain RecG_N PF17190.4 CDJ80738.1 - 6.9 7.5 7.9 0.97 10.2 0.9 3.0 3 0 0 3 3 3 0 RecG N-terminal helical domain WD40 PF00400.32 CDJ80739.1 - 1.2e-10 41.7 15.2 0.0054 17.6 0.5 5.6 7 0 0 7 7 7 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CDJ80739.1 - 0.0052 15.8 1.1 1.2 8.0 0.0 2.9 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4459 PF14673.6 CDJ80739.1 - 0.0092 15.9 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4459) PGM_PMM_I PF02878.16 CDJ80740.1 - 1.9e-38 131.3 0.0 4.5e-38 130.1 0.0 1.6 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 CDJ80740.1 - 3.2e-21 75.9 0.0 9.2e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 CDJ80740.1 - 5.6e-12 45.9 0.0 9.8e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 CDJ80740.1 - 1.1e-08 35.1 0.0 3.8e-08 33.4 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Aa_trans PF01490.18 CDJ80741.1 - 7e-68 229.2 31.8 8.8e-68 228.9 31.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Mito_carr PF00153.27 CDJ80742.1 - 2.5e-51 171.6 1.4 3e-21 75.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MCD PF05292.11 CDJ80743.1 - 1.8e-83 280.0 0.0 2.1e-83 279.8 0.0 1.0 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain Exo_endo_phos_2 PF14529.6 CDJ80744.1 - 3e-08 33.5 0.0 7.3e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ80744.1 - 0.0028 17.2 0.1 0.0036 16.8 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 CDJ80745.1 - 1.5e-74 250.7 0.1 5.1e-36 124.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ80745.1 - 1.9e-41 142.0 0.0 1.9e-19 69.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDJ80745.1 - 4.6e-10 39.3 0.3 0.0016 17.8 0.0 3.4 4 2 0 4 4 4 2 Kinase-like APH PF01636.23 CDJ80745.1 - 4.8e-06 26.7 0.1 1.5 8.7 0.0 4.0 2 2 2 4 4 4 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ80745.1 - 2.8e-05 23.1 0.0 0.23 10.2 0.0 2.4 2 0 0 2 2 2 2 Fungal protein kinase Haspin_kinase PF12330.8 CDJ80745.1 - 0.00046 19.3 0.5 0.79 8.6 0.1 2.3 2 0 0 2 2 2 2 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 CDJ80745.1 - 0.079 12.5 0.0 16 4.9 0.0 2.3 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL CpXC PF14353.6 CDJ80745.1 - 0.099 12.7 0.0 26 4.9 0.0 2.5 2 0 0 2 2 2 0 CpXC protein GST_C_6 PF17171.4 CDJ80745.1 - 0.13 12.1 0.1 2.6e+02 1.5 0.0 4.1 4 0 0 4 4 4 0 Glutathione S-transferase, C-terminal domain DUF2661 PF10860.8 CDJ80745.1 - 0.25 11.5 6.5 6.2 7.0 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2661) Kinesin PF00225.23 CDJ80746.1 - 1.8e-100 336.1 0.0 1.8e-100 336.1 0.0 3.4 3 1 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 CDJ80746.1 - 1.1e-26 93.6 2.8 6.2e-26 91.1 0.0 3.0 2 0 0 2 2 2 1 Microtubule binding DUF4164 PF13747.6 CDJ80746.1 - 0.0012 19.1 1.9 0.0012 19.1 1.9 8.6 3 3 8 11 11 11 1 Domain of unknown function (DUF4164) DUF3677 PF12432.8 CDJ80747.1 - 3.8e-14 52.8 0.7 3.8e-14 52.8 0.7 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3677) DUF727 PF05303.12 CDJ80748.1 - 2.1e-34 117.8 0.0 3.1e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF727) Cadherin PF00028.17 CDJ80749.1 - 0.1 13.1 0.0 0.38 11.2 0.0 2.0 2 0 0 2 2 2 0 Cadherin domain Coatamer_beta_C PF07718.12 CDJ80749.1 - 0.11 12.4 0.4 0.28 11.1 0.4 1.6 1 0 0 1 1 1 0 Coatomer beta C-terminal region EF-hand_1 PF00036.32 CDJ80750.1 - 7.6e-26 87.7 0.9 5.9e-07 28.6 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ80750.1 - 1.8e-22 79.6 0.0 3.4e-11 43.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ80750.1 - 2.2e-19 67.7 0.2 0.00023 20.9 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CDJ80750.1 - 4.1e-18 65.0 2.4 0.00026 20.8 0.0 4.3 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CDJ80750.1 - 8e-18 63.1 0.4 5.6e-06 25.6 0.0 4.3 4 0 0 4 4 4 4 EF hand SPARC_Ca_bdg PF10591.9 CDJ80750.1 - 2.6e-08 34.1 0.2 2.5e-05 24.6 0.1 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CDJ80750.1 - 5.4e-05 23.1 0.1 0.00051 20.0 0.0 2.3 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 CDJ80750.1 - 0.0045 16.8 0.1 3.7 7.5 0.0 3.2 3 1 0 3 3 3 1 EF hand DUF2267 PF10025.9 CDJ80750.1 - 0.01 16.1 0.0 8.4 6.7 0.0 2.8 2 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2267) Mu-like_Pro PF10123.9 CDJ80750.1 - 0.037 13.6 0.6 0.062 12.8 0.3 1.4 1 1 0 1 1 1 0 Mu-like prophage I protein TerB PF05099.13 CDJ80750.1 - 0.06 13.3 0.0 1.6 8.7 0.0 2.3 2 1 0 2 2 2 0 Tellurite resistance protein TerB Caleosin PF05042.13 CDJ80750.1 - 0.1 12.5 0.1 14 5.6 0.0 2.8 1 1 2 3 3 3 0 Caleosin related protein Glyco_hydro_16 PF00722.21 CDJ80750.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 DUF5638 PF18688.1 CDJ80750.1 - 0.15 12.4 4.1 2.6 8.4 0.1 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF5638) Frag1 PF10277.9 CDJ80751.1 - 4.2e-05 23.2 18.8 6.4e-05 22.6 18.8 1.2 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family rve PF00665.26 CDJ80752.1 - 4.4e-24 84.9 0.0 7.9e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ80752.1 - 9.4e-18 64.1 0.2 2.9e-17 62.5 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CDJ80752.1 - 1.5e-05 24.7 0.0 4.1e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.6 CDJ80752.1 - 0.00068 19.4 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-H2C2 PF09337.10 CDJ80752.1 - 0.092 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 H2C2 zinc finger TPR_1 PF00515.28 CDJ80753.1 - 4.3e-37 124.4 28.9 0.00028 20.6 0.0 13.4 14 0 0 14 14 14 10 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ80753.1 - 5.8e-32 107.2 40.4 0.00029 20.7 0.0 15.6 17 0 0 17 17 17 7 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ80753.1 - 5e-29 100.6 15.5 0.00037 20.9 0.3 10.2 7 2 2 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ80753.1 - 3.8e-25 87.3 0.4 0.026 14.2 0.0 11.1 10 1 1 11 11 11 7 TPR repeat TPR_12 PF13424.6 CDJ80753.1 - 6.8e-23 80.8 22.8 0.00046 20.4 0.3 9.9 6 3 2 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ80753.1 - 3.4e-21 73.6 30.7 0.0044 17.1 0.4 12.8 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ80753.1 - 1.6e-20 73.5 4.2 2.9e-05 24.6 0.0 7.9 4 3 3 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ80753.1 - 4.8e-17 61.2 24.9 0.29 12.1 0.0 13.4 10 3 4 14 14 12 4 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ80753.1 - 2.6e-16 58.7 16.7 1.2 9.7 0.0 14.4 16 0 0 16 16 15 4 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ80753.1 - 1.7e-11 44.0 20.8 0.23 12.2 0.0 10.8 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ80753.1 - 1e-09 37.7 25.4 0.12 12.4 0.2 11.0 12 0 0 12 12 11 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ80753.1 - 2.4e-08 34.1 16.1 0.0019 18.4 0.2 6.4 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CDJ80753.1 - 4.1e-06 26.8 3.1 1.1 9.5 0.1 6.2 6 1 0 6 6 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ80753.1 - 3e-05 24.0 2.8 0.31 11.1 0.0 6.1 6 0 0 6 6 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 CDJ80753.1 - 0.00013 21.7 21.6 0.2 11.6 1.3 9.5 11 0 0 11 11 11 1 Tetratricopeptide repeat Sel1 PF08238.12 CDJ80753.1 - 0.0027 18.3 8.2 0.31 11.8 1.6 5.2 4 0 0 4 4 4 1 Sel1 repeat ANAPC5 PF12862.7 CDJ80753.1 - 0.01 15.9 10.6 0.54 10.4 0.1 4.9 5 1 0 6 6 5 0 Anaphase-promoting complex subunit 5 ABC2_membrane PF01061.24 CDJ80754.1 - 1.3e-24 86.9 25.9 1.3e-24 86.9 25.9 2.1 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 CDJ80754.1 - 1.5e-23 83.8 0.1 3.4e-23 82.7 0.1 1.6 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 CDJ80754.1 - 3.8e-05 23.7 0.0 9.4e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 CDJ80754.1 - 0.00011 22.2 1.2 0.15 11.8 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CDJ80754.1 - 0.00071 19.3 0.2 0.0043 16.8 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CDJ80754.1 - 0.0089 16.1 0.2 0.024 14.7 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 CDJ80754.1 - 0.021 15.1 0.0 0.053 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CDJ80754.1 - 0.021 15.1 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain GPR_Gpa2_C PF11970.8 CDJ80754.1 - 0.022 14.8 2.2 0.088 12.9 2.2 2.1 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term AAA_16 PF13191.6 CDJ80754.1 - 0.028 14.8 0.0 0.048 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 CDJ80754.1 - 0.035 14.3 0.0 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CDJ80754.1 - 0.038 14.5 0.0 0.07 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 CDJ80754.1 - 0.048 12.6 0.0 0.091 11.7 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CDJ80754.1 - 0.049 14.2 0.1 0.11 13.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain RepC PF06504.11 CDJ80754.1 - 0.057 12.6 0.0 1.3 8.1 0.0 2.6 3 0 0 3 3 3 0 Replication protein C (RepC) AAA_25 PF13481.6 CDJ80754.1 - 0.076 12.6 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CDJ80754.1 - 0.08 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain cobW PF02492.19 CDJ80754.1 - 0.13 11.9 0.2 0.31 10.6 0.2 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 CDJ80754.1 - 0.31 10.4 0.9 4.1 6.8 0.9 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain ABC2_membrane PF01061.24 CDJ80755.1 - 4.3e-26 91.6 21.9 4.3e-26 91.6 21.9 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 CDJ80755.1 - 2.1e-21 76.9 0.0 5.3e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CDJ80755.1 - 0.0002 21.3 0.0 0.26 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDJ80755.1 - 0.0015 18.0 0.2 0.011 15.2 0.2 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CDJ80755.1 - 0.0017 18.3 0.1 0.0049 16.8 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 CDJ80755.1 - 0.0094 16.5 0.0 0.028 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDJ80755.1 - 0.01 16.1 0.0 0.037 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 CDJ80755.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 CDJ80755.1 - 0.024 14.3 0.1 0.056 13.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 CDJ80755.1 - 0.031 14.5 0.0 0.075 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CDJ80755.1 - 0.034 14.3 0.0 0.088 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain EF-hand_like PF09279.11 CDJ80755.1 - 0.068 13.7 0.1 0.61 10.6 0.0 2.3 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like AAA_16 PF13191.6 CDJ80755.1 - 0.069 13.5 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 CDJ80755.1 - 0.13 12.1 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 CDJ80755.1 - 0.23 11.9 0.1 0.23 11.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 CDJ80755.1 - 0.86 8.6 3.3 1.9 7.5 0.8 2.3 1 1 1 2 2 2 0 Type II/IV secretion system protein GKAP PF03359.13 CDJ80755.1 - 0.92 9.0 6.1 1.4 8.4 6.1 1.2 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein Astacin PF01400.24 CDJ80756.1 - 1.3e-12 47.7 0.1 1.8e-12 47.3 0.1 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) DUF1264 PF06884.11 CDJ80756.1 - 0.044 13.4 0.1 0.055 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1264) UQ_con PF00179.26 CDJ80757.1 - 1.2e-16 60.7 0.0 1.7e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme INTS5_C PF14838.6 CDJ80759.1 - 3.6e-56 191.2 1.0 5.9e-56 190.5 1.0 1.4 1 0 0 1 1 1 1 Integrator complex subunit 5 C-terminus INTS5_N PF14837.6 CDJ80759.1 - 6.5e-33 114.1 0.1 1.7e-32 112.7 0.1 1.7 1 0 0 1 1 1 1 Integrator complex subunit 5 N-terminus DUF5020 PF16412.5 CDJ80759.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5020) Aldolase_II PF00596.21 CDJ80760.1 - 2.1e-44 151.7 0.1 2.7e-44 151.3 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Glycos_transf_1 PF00534.20 CDJ80760.1 - 0.054 13.0 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 Trypan_PARP PF05887.11 CDJ80761.1 - 1.1e-05 25.4 96.2 0.13 12.3 12.8 5.4 2 1 3 5 5 5 4 Procyclic acidic repetitive protein (PARP) SNARE_assoc PF09335.11 CDJ80762.1 - 2.7e-18 66.6 5.4 2.7e-18 66.6 5.4 1.5 2 0 0 2 2 2 1 SNARE associated Golgi protein Patched PF02460.18 CDJ80763.1 - 6.1e-203 676.2 15.5 7.7e-203 675.9 15.5 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 CDJ80763.1 - 1.9e-35 122.0 22.5 2.9e-34 118.1 5.7 3.3 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation SecD_SecF PF02355.16 CDJ80763.1 - 0.1 12.0 23.3 0.69 9.3 5.8 2.4 2 0 0 2 2 2 0 Protein export membrane protein MMPL PF03176.15 CDJ80763.1 - 2.1 7.2 16.1 0.04 12.8 4.3 2.4 2 0 0 2 2 2 0 MMPL family Bestrophin PF01062.21 CDJ80765.1 - 5.4e-89 298.5 5.1 6.6e-89 298.2 5.1 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Ribosomal_L18 PF17135.4 CDJ80766.1 - 6.6e-91 302.8 2.1 7.4e-91 302.6 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CDJ80766.1 - 0.046 14.4 0.2 0.15 12.7 0.2 1.9 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Pkinase PF00069.25 CDJ80767.1 - 2.1e-55 188.0 0.0 2.4e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ80767.1 - 5e-40 137.4 0.0 6.2e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ80767.1 - 2.6e-06 27.0 0.0 4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 CDJ80767.1 - 0.0059 15.7 0.0 0.009 15.1 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 CDJ80767.1 - 0.016 14.2 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 CDJ80767.1 - 0.12 11.9 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 CDJ80767.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ricin_B_lectin PF00652.22 CDJ80768.1 - 2.9e-25 89.0 0.1 5.1e-25 88.2 0.1 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glycos_transf_2 PF00535.26 CDJ80768.1 - 5.9e-13 49.0 0.0 2e-09 37.5 0.0 2.3 1 1 1 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 CDJ80768.1 - 6.4e-05 22.5 0.4 0.00014 21.4 0.4 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase PP2C PF00481.21 CDJ80769.1 - 1.3e-32 113.4 0.7 4e-16 59.4 0.0 4.0 2 1 1 3 3 3 3 Protein phosphatase 2C SpoIIE PF07228.12 CDJ80769.1 - 0.00058 19.8 0.0 0.038 13.9 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Ribosomal_L34e PF01199.18 CDJ80770.1 - 1.3e-39 134.4 4.5 1.6e-39 134.1 4.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e Vps8 PF12816.7 CDJ80772.1 - 1.4e-45 155.2 0.0 8e-45 152.8 0.0 2.1 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 ANAPC4_WD40 PF12894.7 CDJ80772.1 - 0.0083 16.4 0.0 0.037 14.3 0.0 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_5 PF14634.6 CDJ80772.1 - 0.059 13.3 7.3 0.18 11.8 7.3 1.9 1 0 0 1 1 1 0 zinc-RING finger domain PQQ_2 PF13360.6 CDJ80772.1 - 0.22 11.1 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 PQQ-like domain zf-RING_2 PF13639.6 CDJ80772.1 - 1.7 9.0 6.8 7 7.1 6.8 2.1 1 0 0 1 1 1 0 Ring finger domain NTP_transferase PF00483.23 CDJ80773.1 - 3.7e-51 174.1 0.0 4.7e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CDJ80773.1 - 1.4e-13 50.0 9.6 2.5e-08 33.3 1.4 2.8 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CDJ80773.1 - 1.1e-10 42.0 0.0 1.5e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 CDJ80773.1 - 6.3e-06 25.8 9.5 6.3e-05 22.6 1.7 2.9 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 CDJ80773.1 - 0.068 11.3 0.3 0.17 10.0 0.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) IspD PF01128.19 CDJ80773.1 - 0.14 11.8 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase zf-C2H2 PF00096.26 CDJ80774.1 - 0.13 12.8 6.1 1.3 9.7 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ80774.1 - 0.16 12.8 9.0 1.9 9.6 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-FCS PF06467.14 CDJ80774.1 - 1.8 8.6 5.7 8 6.5 0.7 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif GST_N PF02798.20 CDJ80775.1 - 8.4e-14 51.7 0.0 2e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CDJ80775.1 - 4.7e-13 49.2 0.0 7.4e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDJ80775.1 - 2e-05 24.7 0.0 3.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDJ80775.1 - 0.00073 19.9 0.0 0.0018 18.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 CDJ80775.1 - 0.0013 19.4 0.0 0.0028 18.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.6 CDJ80775.1 - 0.024 14.9 0.0 0.069 13.5 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DUF1908 PF08926.11 CDJ80776.1 - 3.3e-72 243.0 3.1 3.3e-72 243.0 3.1 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF1908) Pkinase PF00069.25 CDJ80776.1 - 4.6e-65 219.6 0.0 7.9e-65 218.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ80776.1 - 3.7e-29 101.8 0.0 9.9e-29 100.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase PDZ_6 PF17820.1 CDJ80776.1 - 1.2e-10 41.0 0.0 2.7e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CDJ80776.1 - 1.9e-09 37.8 0.0 3.5e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ80776.1 - 7e-07 29.5 0.0 1.5e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain APH PF01636.23 CDJ80776.1 - 6.6e-06 26.2 0.0 0.057 13.3 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CDJ80776.1 - 3.9e-05 23.1 0.0 0.00013 21.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CDJ80776.1 - 0.026 13.5 0.0 0.048 12.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_C PF00433.24 CDJ80776.1 - 0.063 14.0 0.5 0.3 11.8 0.1 2.6 2 0 0 2 2 2 0 Protein kinase C terminal domain Kdo PF06293.14 CDJ80776.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HTH_Tnp_Tc3_2 PF01498.18 CDJ80777.1 - 1.9e-25 88.9 0.5 3.3e-25 88.1 0.5 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 CDJ80777.1 - 3.7e-05 24.2 6.2 0.00018 22.1 0.4 2.5 1 1 1 2 2 2 1 Homeodomain-like domain PAX PF00292.18 CDJ80777.1 - 4.4e-05 23.4 0.1 6.5e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 'Paired box' domain HTH_24 PF13412.6 CDJ80777.1 - 0.0073 15.8 1.3 0.36 10.4 0.1 3.0 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_21 PF13276.6 CDJ80777.1 - 0.088 13.0 0.1 0.29 11.3 0.1 2.0 1 1 0 1 1 1 0 HTH-like domain TrmB PF01978.19 CDJ80777.1 - 0.23 11.4 0.1 5.7 6.9 0.1 2.4 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_23 PF13384.6 CDJ80777.1 - 0.36 10.7 0.1 0.36 10.7 0.1 3.1 4 0 0 4 4 4 0 Homeodomain-like domain DDE_3 PF13358.6 CDJ80778.1 - 1.5e-09 37.8 0.4 1.9e-09 37.5 0.4 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease TerB PF05099.13 CDJ80778.1 - 0.064 13.2 0.0 0.084 12.8 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TerB Nterm_IS4 PF13006.7 CDJ80779.1 - 0.068 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Insertion element 4 transposase N-terminal DUF148 PF02520.17 CDJ80784.1 - 4.9e-28 97.4 6.8 5.8e-28 97.2 6.8 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 Metal_resist PF13801.6 CDJ80784.1 - 3.4e-05 24.0 0.9 0.00056 20.1 0.0 3.0 1 1 2 3 3 3 1 Heavy-metal resistance Baculo_PEP_C PF04513.12 CDJ80784.1 - 0.00097 19.2 1.6 0.0014 18.6 1.6 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5304 PF17230.2 CDJ80784.1 - 0.0077 16.5 0.7 0.013 15.7 0.5 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF5304) Fib_alpha PF08702.10 CDJ80784.1 - 0.016 15.4 1.2 0.022 15.0 1.2 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF241 PF03087.14 CDJ80784.1 - 0.031 14.1 0.2 0.04 13.7 0.2 1.1 1 0 0 1 1 1 0 Arabidopsis protein of unknown function HEPN_AbiA_CTD PF18732.1 CDJ80784.1 - 0.044 13.7 0.1 0.063 13.2 0.1 1.2 1 0 0 1 1 1 0 HEPN like, Abia C-terminal domain DUF1664 PF07889.12 CDJ80784.1 - 0.05 13.6 1.0 0.074 13.1 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Nod1 PF17114.5 CDJ80784.1 - 0.096 12.8 0.2 0.19 11.9 0.2 1.4 1 1 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 DUF3585 PF12130.8 CDJ80784.1 - 0.1 12.7 1.1 0.14 12.2 1.1 1.1 1 0 0 1 1 1 0 Bivalent Mical/EHBP Rab binding domain DUF16 PF01519.16 CDJ80784.1 - 0.12 12.9 1.6 0.28 11.7 1.6 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF1525 PF07511.11 CDJ80784.1 - 0.15 12.2 1.2 0.2 11.8 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) FAD-SLDH PF12318.8 CDJ80784.1 - 0.22 11.6 3.4 0.45 10.6 0.3 2.0 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Peptidase_S64 PF08192.11 CDJ80784.1 - 0.23 9.9 1.3 0.27 9.7 1.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 Phage_GPO PF05929.11 CDJ80784.1 - 0.24 11.0 2.1 0.31 10.6 2.1 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase F_actin_bind PF08919.10 CDJ80784.1 - 0.26 11.4 2.1 9.9 6.3 0.3 2.1 1 1 1 2 2 2 0 F-actin binding BST2 PF16716.5 CDJ80784.1 - 0.6 10.7 2.8 16 6.1 0.3 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 NPV_P10 PF05531.12 CDJ80784.1 - 0.91 10.0 3.9 3 8.4 3.7 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein LPP PF04728.13 CDJ80784.1 - 2.1 8.8 4.2 21 5.6 0.2 2.4 1 1 1 2 2 2 0 Lipoprotein leucine-zipper DUF148 PF02520.17 CDJ80785.1 - 4.6e-27 94.3 5.4 6.2e-27 93.9 5.4 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 THP2 PF09432.10 CDJ80785.1 - 0.0041 17.2 4.1 0.013 15.5 1.0 2.2 1 1 1 2 2 2 1 Tho complex subunit THP2 Mer2 PF09074.10 CDJ80785.1 - 0.011 15.6 4.0 0.018 14.9 4.0 1.3 1 0 0 1 1 1 0 Mer2 NB-ARC PF00931.22 CDJ80785.1 - 0.027 13.7 0.4 0.036 13.2 0.4 1.1 1 0 0 1 1 1 0 NB-ARC domain RsbRD_N PF14361.6 CDJ80785.1 - 0.055 14.2 0.4 0.1 13.3 0.4 1.4 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain DUF4268 PF14088.6 CDJ80785.1 - 0.057 13.3 2.8 0.094 12.6 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) HSCB_C PF07743.13 CDJ80785.1 - 0.075 13.5 1.7 0.17 12.4 1.7 1.6 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain EcoEI_R_C PF08463.10 CDJ80785.1 - 0.088 12.9 3.2 2.7 8.1 0.4 2.1 1 1 1 2 2 2 0 EcoEI R protein C-terminal Terminase_6C PF17289.2 CDJ80785.1 - 0.11 12.6 0.6 0.25 11.4 0.4 1.6 1 1 0 1 1 1 0 Terminase RNaseH-like domain Sigma70_ner PF04546.13 CDJ80785.1 - 1.5 8.6 10.4 0.29 11.0 3.3 2.3 2 1 0 2 2 2 0 Sigma-70, non-essential region DUF148 PF02520.17 CDJ80786.1 - 1.8e-24 86.0 6.4 2.1e-24 85.7 6.4 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 Tam41_Mmp37 PF09139.11 CDJ80786.1 - 0.13 11.7 1.9 0.17 11.3 1.9 1.0 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial BAG PF02179.16 CDJ80786.1 - 0.14 12.6 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 BAG domain DUF148 PF02520.17 CDJ80787.1 - 4.6e-24 84.6 9.5 5.4e-24 84.4 9.5 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF148 KapB PF08810.10 CDJ80787.1 - 0.0012 18.9 0.5 0.0018 18.4 0.5 1.3 1 0 0 1 1 1 1 Kinase associated protein B DUF4407 PF14362.6 CDJ80787.1 - 0.0039 16.6 1.7 0.0045 16.4 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) SHE3 PF17078.5 CDJ80787.1 - 0.0096 15.7 3.2 0.015 15.0 3.2 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 DUF2508 PF10704.9 CDJ80787.1 - 0.011 15.9 2.5 0.018 15.2 2.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2508) DUF5098 PF17023.5 CDJ80787.1 - 0.014 14.3 2.5 0.018 14.0 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5098) DUF4404 PF14357.6 CDJ80787.1 - 0.016 15.8 4.0 1.9 9.2 0.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF1664 PF07889.12 CDJ80787.1 - 0.019 15.0 1.3 0.027 14.5 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2130 PF09903.9 CDJ80787.1 - 0.036 13.3 5.3 0.046 13.0 5.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) Helo_like_N PF17111.5 CDJ80787.1 - 0.039 13.3 3.0 0.051 12.9 3.0 1.1 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Jnk-SapK_ap_N PF09744.9 CDJ80787.1 - 0.058 13.6 1.8 0.074 13.3 1.8 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Maf1 PF09174.10 CDJ80787.1 - 0.073 13.2 2.5 0.093 12.9 1.7 1.5 2 0 0 2 2 2 0 Maf1 regulator RhoGAP PF00620.27 CDJ80787.1 - 0.1 12.4 0.8 0.42 10.4 0.8 2.0 1 1 0 1 1 1 0 RhoGAP domain HsdM_N PF12161.8 CDJ80787.1 - 0.12 12.9 4.0 0.28 11.8 3.6 1.8 1 1 1 2 2 2 0 HsdM N-terminal domain DUF2321 PF10083.9 CDJ80787.1 - 0.14 11.8 0.6 0.2 11.2 0.6 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) OmpH PF03938.14 CDJ80787.1 - 0.16 12.3 7.0 0.18 12.2 6.0 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 CDJ80787.1 - 0.17 11.4 1.0 0.21 11.1 1.0 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Totivirus_coat PF05518.11 CDJ80787.1 - 0.34 8.9 0.4 0.3 9.1 0.4 1.2 1 0 0 1 1 1 0 Totivirus coat protein TolA_bind_tri PF16331.5 CDJ80787.1 - 0.73 10.0 3.8 0.84 9.8 0.3 2.2 1 1 1 2 2 2 0 TolA binding protein trimerisation Prominin PF05478.11 CDJ80787.1 - 1 7.2 3.7 1.3 6.8 3.2 1.3 1 1 0 1 1 1 0 Prominin BRE1 PF08647.11 CDJ80787.1 - 1.3 9.1 9.8 5.3 7.2 3.6 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Metal_resist PF13801.6 CDJ80787.1 - 5.2 7.3 5.9 20 5.4 0.0 3.6 2 1 1 3 3 3 0 Heavy-metal resistance HSP20 PF00011.21 CDJ80789.1 - 1.6e-22 79.6 1.1 1.8e-22 79.4 1.1 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ80789.1 - 5e-05 22.8 0.1 6.8e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA TRM13 PF05206.14 CDJ80790.1 - 3.5e-56 190.6 0.0 6.5e-56 189.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase TRM13 CDP-OH_P_transf PF01066.21 CDJ80790.1 - 6.5e-16 58.9 0.1 6.5e-16 58.9 0.1 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase zf-U11-48K PF05253.12 CDJ80790.1 - 0.00023 21.0 4.2 0.00067 19.5 4.2 1.9 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.6 CDJ80790.1 - 0.00099 19.1 2.2 0.0078 16.2 2.2 2.2 1 1 0 1 1 1 1 Methyltransferase domain Pro_isomerase PF00160.21 CDJ80791.1 - 2.9e-49 167.4 0.1 3.3e-49 167.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LSM14 PF12701.7 CDJ80796.1 - 1.6e-30 105.0 0.0 2.7e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 CDJ80796.1 - 8.5e-12 45.9 15.1 8.5e-12 45.9 15.1 2.1 2 1 0 2 2 2 1 FDF domain SM-ATX PF14438.6 CDJ80796.1 - 3.4e-09 36.7 0.0 6.6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF4605 PF15378.6 CDJ80797.1 - 1.9 8.4 8.2 2.5 8.0 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4605) DUF4499 PF14934.6 CDJ80798.1 - 4.1e-17 62.3 4.8 5.3e-17 61.9 4.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) LSM14 PF12701.7 CDJ80799.1 - 2e-30 104.7 0.0 3.5e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 CDJ80799.1 - 1.1e-11 45.5 15.1 1.1e-11 45.5 15.1 2.1 2 1 0 2 2 2 1 FDF domain SM-ATX PF14438.6 CDJ80799.1 - 4.4e-09 36.3 0.0 8.4e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain Mucin-like PF16058.5 CDJ80799.1 - 0.3 11.2 7.2 0.69 10.0 7.2 1.6 1 0 0 1 1 1 0 Mucin-like Dopey_N PF04118.14 CDJ80800.1 - 8.3e-98 327.3 0.1 2.2e-97 325.9 0.0 1.8 2 0 0 2 2 2 1 Dopey, N-terminal RVT_1 PF00078.27 CDJ80802.1 - 2e-08 34.0 0.0 2.9e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NPP PF08384.10 CDJ80803.1 - 0.12 12.4 0.1 0.12 12.4 0.1 3.3 3 1 1 4 4 4 0 Pro-opiomelanocortin, N-terminal region Gal-bind_lectin PF00337.22 CDJ80804.1 - 1.7e-46 157.0 0.1 5.9e-24 84.1 0.0 2.0 2 0 0 2 2 2 2 Galactoside-binding lectin Transposase_1 PF01359.18 CDJ80805.1 - 3.7e-16 58.7 0.1 2e-15 56.4 0.0 2.1 2 0 0 2 2 2 1 Transposase (partial DDE domain) DDE_3 PF13358.6 CDJ80805.1 - 5.2e-07 29.5 0.1 8.1e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 CDJ80805.1 - 0.0091 16.2 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain 7tm_1 PF00001.21 CDJ80806.1 - 1.8e-15 57.0 4.8 1.8e-15 57.0 4.8 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 CDJ80806.1 - 0.001 18.9 8.8 0.0013 18.6 8.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 CDJ80806.1 - 0.0049 16.3 7.6 0.0064 15.9 7.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx GAPT PF11770.8 CDJ80807.1 - 0.00015 21.7 0.1 0.00022 21.1 0.1 1.3 1 0 0 1 1 1 1 GRB2-binding adapter (GAPT) DUF4131 PF13567.6 CDJ80807.1 - 0.022 14.4 0.1 0.029 14.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Chordopox_A13L PF05961.11 CDJ80807.1 - 0.17 12.2 1.0 0.31 11.3 0.1 1.9 1 1 1 2 2 2 0 Chordopoxvirus A13L protein FixQ PF05545.11 CDJ80807.1 - 0.26 11.3 0.3 0.42 10.6 0.3 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ 7tm_1 PF00001.21 CDJ80808.1 - 2.9e-06 26.8 0.1 3.4e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDJ80808.1 - 0.014 14.7 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Peptidase_M28 PF04389.17 CDJ80809.1 - 4e-22 78.9 0.0 1.1e-21 77.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.15 CDJ80809.1 - 1.9e-15 57.0 0.0 4.3e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.22 CDJ80809.1 - 1.1e-13 51.0 0.0 7.3e-13 48.4 0.0 2.2 2 0 0 2 2 2 1 PA domain Phage_F PF02305.17 CDJ80809.1 - 0.042 12.6 0.1 0.074 11.8 0.1 1.3 1 0 0 1 1 1 0 Capsid protein (F protein) Nicastrin PF05450.15 CDJ80809.1 - 0.067 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Nicastrin Globin PF00042.22 CDJ80810.1 - 0.0033 18.0 0.2 0.0063 17.1 0.2 1.5 1 0 0 1 1 1 1 Globin Metal_resist PF13801.6 CDJ80810.1 - 0.043 14.0 0.1 0.69 10.1 0.0 2.2 2 0 0 2 2 2 0 Heavy-metal resistance PE PF00934.20 CDJ80810.1 - 0.058 13.7 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 PE family 7TM_GPCR_Srab PF10292.9 CDJ80811.1 - 0.036 13.0 0.6 0.041 12.8 0.6 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Srab PF10292.9 CDJ80812.1 - 4.4e-39 134.3 11.5 4.9e-39 134.1 11.5 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Sra PF02117.16 CDJ80812.1 - 9.4e-18 64.1 13.2 1.1e-17 63.9 13.2 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sra 7TM_GPCR_Srb PF02175.16 CDJ80812.1 - 3e-07 30.5 6.0 3e-07 30.5 6.0 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srb TIM21 PF08294.11 CDJ80813.1 - 0.066 13.1 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 TIM21 THUMP PF02926.17 CDJ80814.1 - 1.3e-10 41.5 0.0 1.6e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 THUMP domain Acetyltransf_7 PF13508.7 CDJ80815.1 - 0.00041 20.7 0.0 0.0007 20.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDJ80815.1 - 0.0024 17.8 0.0 0.0055 16.6 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDJ80815.1 - 0.051 13.8 0.0 0.071 13.3 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family PTS_EIIA_1 PF00358.20 CDJ80815.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 AMOP PF03782.17 CDJ80817.1 - 1.2e-17 64.4 0.1 1.9e-17 63.7 0.1 1.3 1 0 0 1 1 1 1 AMOP domain NIDO PF06119.14 CDJ80817.1 - 7e-17 62.1 0.1 1.4e-16 61.2 0.1 1.5 1 0 0 1 1 1 1 Nidogen-like TFIIA_gamma_N PF02268.16 CDJ80818.1 - 7.3e-18 64.3 0.2 1.1e-17 63.7 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 CDJ80818.1 - 5.7e-16 58.4 1.1 8.9e-16 57.8 1.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Pkinase PF00069.25 CDJ80819.1 - 8.6e-35 120.4 0.0 1.3e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DCX PF03607.17 CDJ80819.1 - 5.2e-31 106.5 0.0 2.7e-15 56.2 0.0 2.5 2 0 0 2 2 2 2 Doublecortin Pkinase_Tyr PF07714.17 CDJ80819.1 - 2.3e-10 40.2 0.0 3.7e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ80819.1 - 0.039 12.7 0.0 0.095 11.5 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Fringe PF02434.16 CDJ80820.1 - 2.5e-15 56.6 0.5 4.1e-14 52.6 0.5 2.0 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 CDJ80820.1 - 2.1e-12 47.3 1.2 2e-07 31.0 0.2 3.0 1 1 2 3 3 3 2 Galactosyltransferase Membralin PF09746.9 CDJ80821.1 - 1.5e-134 448.8 3.8 2e-134 448.4 3.8 1.1 1 0 0 1 1 1 1 Tumour-associated protein MTS PF05175.14 CDJ80822.1 - 2.3e-13 50.0 0.0 2e-12 47.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CDJ80822.1 - 4.5e-08 33.7 0.0 9e-08 32.7 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ80822.1 - 1.2e-06 28.4 0.0 1.7e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CDJ80822.1 - 2.3e-06 27.2 0.0 3.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 CDJ80822.1 - 9.9e-05 21.8 0.0 0.00012 21.5 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_11 PF08241.12 CDJ80822.1 - 0.00022 21.8 0.1 0.00069 20.2 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ80822.1 - 0.00033 21.3 0.1 0.00083 20.1 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 CDJ80822.1 - 0.00054 19.7 0.0 0.00073 19.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_24 PF13578.6 CDJ80822.1 - 0.0033 18.4 0.0 0.0063 17.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 CDJ80822.1 - 0.056 12.5 0.0 0.069 12.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Met_10 PF02475.16 CDJ80822.1 - 0.072 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PCMT PF01135.19 CDJ80822.1 - 0.081 12.7 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 CDJ80822.1 - 0.098 12.5 0.0 0.15 11.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Galactosyl_T PF01762.21 CDJ80823.1 - 3.2e-15 56.5 0.0 3.7e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 Galactosyltransferase HTH_48 PF17906.1 CDJ80825.1 - 2e-18 66.2 0.6 4.7e-18 65.0 0.6 1.7 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_Tnp_IS630 PF01710.16 CDJ80825.1 - 3.5e-07 30.3 0.0 4.4e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 CDJ80825.1 - 1.3e-06 28.9 0.1 3.8e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.6 CDJ80825.1 - 3e-05 23.7 0.0 6.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 CDJ80825.1 - 3.6e-05 23.4 0.3 0.023 14.5 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 CDJ80825.1 - 0.0001 22.5 0.2 0.0004 20.6 0.1 1.9 2 0 0 2 2 2 1 Transposase HTH_50 PF18024.1 CDJ80825.1 - 0.00026 20.6 0.0 0.00045 19.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 CDJ80825.1 - 0.00031 20.8 0.0 0.98 9.6 0.0 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_29 PF13551.6 CDJ80825.1 - 0.0019 18.2 0.0 0.52 10.4 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_11 PF08279.12 CDJ80825.1 - 0.0042 17.0 0.0 0.0079 16.1 0.0 1.4 1 0 0 1 1 1 1 HTH domain HTH_Tnp_ISL3 PF13542.6 CDJ80825.1 - 0.0043 16.4 1.5 0.37 10.3 0.1 2.7 2 1 1 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_1 PF01527.20 CDJ80825.1 - 0.01 16.1 0.4 3.8 7.9 0.0 2.2 1 1 1 2 2 2 0 Transposase HTH_40 PF14493.6 CDJ80825.1 - 0.013 16.0 0.1 0.021 15.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain IF2_N PF04760.15 CDJ80825.1 - 0.017 14.9 0.3 0.042 13.7 0.0 1.7 2 0 0 2 2 1 0 Translation initiation factor IF-2, N-terminal region HTH_6 PF01418.17 CDJ80825.1 - 0.039 13.9 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_36 PF13730.6 CDJ80825.1 - 0.042 13.8 0.0 0.17 11.9 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Terminase_5 PF06056.12 CDJ80825.1 - 0.058 13.3 0.2 5.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_5 PF01022.20 CDJ80825.1 - 0.061 13.2 0.1 0.098 12.5 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_10 PF04967.12 CDJ80825.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 HTH DNA binding domain TubC_N PF18563.1 CDJ80825.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 TubC N-terminal docking domain GerE PF00196.19 CDJ80825.1 - 0.14 11.7 0.2 0.29 10.7 0.2 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family NUMOD1 PF07453.13 CDJ80825.1 - 0.19 12.0 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 NUMOD1 domain Phage_terminase PF10668.9 CDJ80825.1 - 0.49 10.4 3.1 0.67 10.0 0.4 2.5 3 1 0 3 3 3 0 Phage terminase small subunit DUF2369 PF10179.9 CDJ80826.1 - 3e-14 53.2 0.2 5.2e-12 46.0 0.1 2.7 3 0 0 3 3 3 2 Uncharacterised conserved protein (DUF2369) fn3 PF00041.21 CDJ80826.1 - 0.011 16.1 0.0 26 5.2 0.0 3.9 3 1 0 3 3 3 0 Fibronectin type III domain HLH PF00010.26 CDJ80827.1 - 1.5e-17 63.3 1.1 2.9e-17 62.4 1.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pex14_N PF04695.13 CDJ80827.1 - 0.93 10.1 6.9 1.4 9.6 6.9 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.25 CDJ80828.1 - 1.7e-71 240.7 0.0 1.9e-71 240.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ80828.1 - 2.7e-34 118.6 0.0 3.4e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ80828.1 - 0.0004 19.5 0.0 0.0025 16.8 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CDJ80828.1 - 0.00055 19.9 0.8 0.0021 18.1 0.4 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CDJ80828.1 - 0.00064 19.1 0.1 0.0042 16.4 0.0 2.0 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 CDJ80828.1 - 0.0072 15.7 1.1 0.014 14.7 1.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CDJ80828.1 - 0.026 13.6 0.1 0.039 13.0 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 CDJ80828.1 - 0.063 12.9 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 CDJ80828.1 - 0.081 12.5 0.1 0.49 10.0 0.1 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 CDJ80828.1 - 0.2 11.2 0.3 0.4 10.2 0.3 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase ABC_membrane PF00664.23 CDJ80829.2 - 6.4e-94 314.6 7.2 3.7e-52 177.7 1.5 2.2 1 1 1 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ80829.2 - 7.7e-32 110.7 0.0 1.4e-31 109.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CDJ80829.2 - 1.6e-06 27.8 0.3 0.00023 20.7 0.0 2.4 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDJ80829.2 - 0.00092 19.6 1.2 0.0047 17.3 1.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 CDJ80829.2 - 0.0027 17.0 0.1 0.016 14.5 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin ABC_ATPase PF09818.9 CDJ80829.2 - 0.0061 15.4 0.0 0.019 13.8 0.0 1.7 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 CDJ80829.2 - 0.0062 16.8 0.2 0.22 11.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 CDJ80829.2 - 0.0075 16.2 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 CDJ80829.2 - 0.024 14.6 0.0 0.076 12.9 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain ATP-synt_ab PF00006.25 CDJ80829.2 - 0.033 13.8 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 CDJ80829.2 - 0.036 13.8 0.1 0.1 12.3 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 CDJ80829.2 - 0.037 13.6 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 CDJ80829.2 - 0.049 14.1 0.0 0.73 10.3 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CDJ80829.2 - 0.063 13.0 0.2 0.67 9.7 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.6 CDJ80829.2 - 0.11 13.0 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CDJ80829.2 - 0.14 12.3 0.0 0.43 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 CDJ80829.2 - 0.15 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_21 PF13304.6 CDJ80829.2 - 0.21 11.4 0.0 1.2 8.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Sod_Cu PF00080.20 CDJ80830.1 - 2.1e-49 167.4 5.9 2.6e-49 167.0 5.9 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.12 CDJ80830.1 - 0.047 14.7 0.7 0.32 12.0 0.7 2.0 1 1 0 1 1 1 0 CHRD domain muHD PF10291.9 CDJ80831.1 - 4.6e-38 131.2 0.0 6.7e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 CDJ80831.1 - 6.8e-10 39.1 2.1 1.1e-08 35.2 0.0 2.8 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain EzrA PF06160.12 CDJ80831.1 - 0.0002 19.7 10.0 0.00034 18.9 10.0 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Adap_comp_sub PF00928.21 CDJ80831.1 - 0.043 13.2 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Adaptor complexes medium subunit family LemA PF04011.12 CDJ80831.1 - 0.054 13.4 6.4 0.19 11.6 6.4 1.9 1 0 0 1 1 1 0 LemA family DUF2185 PF09951.9 CDJ80831.1 - 0.22 11.4 1.3 1.3 8.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2185) TPR_MLP1_2 PF07926.12 CDJ80831.1 - 0.56 10.3 11.2 1.6 8.8 11.2 1.8 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein LMBR1 PF04791.16 CDJ80831.1 - 2.8 6.7 4.8 4.7 6.0 4.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF919 PF06034.11 CDJ80831.1 - 3.7 7.4 5.2 0.73 9.7 0.7 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) RhoGEF PF00621.20 CDJ80831.1 - 4.2 7.6 8.4 10 6.3 7.8 1.9 1 1 0 1 1 1 0 RhoGEF domain Trypan_PARP PF05887.11 CDJ80832.1 - 0.0021 18.0 17.2 0.0021 18.0 17.2 2.5 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) DUF4834 PF16118.5 CDJ80832.1 - 0.78 10.7 8.4 1.3 10.0 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 CDJ80832.1 - 5 7.0 21.4 5.4 6.9 20.6 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SRP-alpha_N PF04086.13 CDJ80832.1 - 6.3 6.6 17.9 0.19 11.6 5.8 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal CLN3 PF02487.17 CDJ80832.1 - 6.6 5.7 6.5 0.55 9.2 0.3 2.0 2 0 0 2 2 2 0 CLN3 protein Hamartin PF04388.12 CDJ80832.1 - 9.5 4.7 30.3 15 4.1 30.3 1.3 1 0 0 1 1 1 0 Hamartin protein Trypan_PARP PF05887.11 CDJ80833.1 - 0.00041 20.3 11.3 0.0005 20.1 11.3 1.1 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) SWI-SNF_Ssr4 PF08549.10 CDJ80833.1 - 0.21 10.2 1.1 0.21 10.2 1.1 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) L51_S25_CI-B8 PF05047.16 CDJ80834.1 - 6.3e-10 38.8 0.0 1.5e-09 37.6 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Zot PF05707.12 CDJ80834.1 - 0.061 13.0 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DDHD PF02862.17 CDJ80835.1 - 0.03 14.5 0.2 0.036 14.2 0.2 1.3 1 0 0 1 1 1 0 DDHD domain RP-C_C PF11800.8 CDJ80835.1 - 0.17 12.0 3.6 0.24 11.5 3.6 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region SRP-alpha_N PF04086.13 CDJ80835.1 - 0.58 10.0 10.9 0.83 9.5 10.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal IHABP4_N PF16174.5 CDJ80835.1 - 3.5 8.2 11.2 5.6 7.5 11.2 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Vfa1 PF08432.10 CDJ80835.1 - 4.1 7.7 11.0 6 7.2 11.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 2-oxoacid_dh PF00198.23 CDJ80836.1 - 7.3e-48 163.0 0.1 8.9e-48 162.8 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 CDJ80836.1 - 2.8e-07 30.8 0.0 8.4e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 e3 binding domain Thioredoxin_8 PF13905.6 CDJ80837.1 - 1.7e-23 82.7 0.0 2.5e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 CDJ80837.1 - 8e-08 32.2 0.0 1.8e-05 24.6 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin AhpC-TSA PF00578.21 CDJ80837.1 - 8e-08 32.2 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDJ80837.1 - 1.1e-05 25.2 0.0 1.3e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 CDJ80837.1 - 0.00073 20.0 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 CDJ80837.1 - 0.014 15.2 0.0 0.1 12.4 0.0 1.9 1 1 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 CDJ80837.1 - 0.12 12.4 0.0 1.3 9.1 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin domain Pkinase PF00069.25 CDJ80838.1 - 1.9e-75 253.7 0.0 2.1e-75 253.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ80838.1 - 2.1e-35 122.2 0.0 2.7e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ80838.1 - 8.8e-05 21.6 0.0 0.00045 19.3 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CDJ80838.1 - 0.00023 21.2 0.0 0.00031 20.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CDJ80838.1 - 0.00071 19.0 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDJ80838.1 - 0.055 12.8 0.1 0.13 11.6 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CDJ80838.1 - 0.2 10.7 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 CDJ80839.1 - 5e-51 173.6 0.0 7.6e-51 173.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ80839.1 - 8.6e-30 103.9 0.0 1.2e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ80839.1 - 1.4e-05 24.6 0.0 2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PIP49_C PF12260.8 CDJ80839.1 - 0.027 14.1 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Pkinase_fungal PF17667.1 CDJ80839.1 - 0.098 11.4 2.5 0.16 10.7 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 CDJ80839.1 - 0.13 11.6 0.1 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IPP-2 PF04979.14 CDJ80840.1 - 0.00078 20.2 10.8 0.0013 19.4 10.5 1.8 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) Granulin PF00396.18 CDJ80842.1 - 0.061 13.7 25.3 2.1 8.7 3.7 3.3 3 0 0 3 3 3 0 Granulin MIT_LIKE_ACTX PF17556.2 CDJ80842.1 - 1.7 9.3 16.2 2.5 8.7 1.8 3.2 3 0 0 3 3 3 0 MIT-like atracotoxin family Kunitz_BPTI PF00014.23 CDJ80843.1 - 5.7e-18 64.9 6.7 6.6e-18 64.7 6.7 1.1 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Kunitz_BPTI PF00014.23 CDJ80844.1 - 1.9e-16 60.0 5.1 2.4e-16 59.7 5.1 1.1 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain PARG_cat PF05028.14 CDJ80847.1 - 2.6e-110 368.9 0.0 4.3e-110 368.2 0.0 1.3 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) zf-C2H2 PF00096.26 CDJ80848.1 - 3.9e-15 55.4 20.7 3.2e-06 27.3 1.4 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ80848.1 - 1.1e-14 54.0 13.3 9.3e-06 25.8 0.0 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDJ80848.1 - 7.5e-12 45.0 18.8 0.0022 18.7 3.9 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDJ80848.1 - 3.1e-06 27.0 21.2 0.0035 17.3 0.4 4.0 3 1 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 CDJ80848.1 - 0.0041 17.4 9.8 0.26 11.6 1.1 2.3 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CDJ80848.1 - 0.0056 17.0 14.2 0.17 12.3 0.3 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-MYND PF01753.18 CDJ80848.1 - 0.0092 16.1 0.0 0.027 14.6 0.0 1.9 1 1 0 1 1 1 1 MYND finger Sina PF03145.16 CDJ80848.1 - 0.022 14.7 4.0 0.028 14.4 3.7 1.4 1 1 0 1 1 1 0 Seven in absentia protein family GAGA PF09237.11 CDJ80848.1 - 0.036 13.9 2.0 0.3 10.9 0.0 2.7 1 1 2 3 3 3 0 GAGA factor DZR PF12773.7 CDJ80848.1 - 0.044 13.8 5.1 0.2 11.7 5.1 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_8 PF15909.5 CDJ80848.1 - 0.045 14.0 1.4 0.045 14.0 1.4 1.9 1 1 1 2 2 2 0 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 CDJ80848.1 - 0.057 13.5 6.3 0.13 12.4 3.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 CDJ80848.1 - 0.067 13.5 9.5 2 8.8 1.6 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Cys_rich_CPXG PF14255.6 CDJ80848.1 - 0.083 12.8 2.7 2.4 8.1 0.3 2.9 3 0 0 3 3 3 0 Cysteine-rich CPXCG CpXC PF14353.6 CDJ80848.1 - 0.11 12.6 6.0 2.3 8.3 0.4 2.2 1 1 1 2 2 2 0 CpXC protein C1_1 PF00130.22 CDJ80848.1 - 0.13 12.2 11.1 4.4 7.3 0.2 3.2 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_jaz PF12171.8 CDJ80848.1 - 0.16 12.3 14.8 0.8 10.1 1.2 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 CDJ80848.1 - 0.25 11.4 16.0 3.6 7.7 2.2 3.4 2 1 1 3 3 3 0 BED zinc finger zf-C2HE PF16278.5 CDJ80848.1 - 0.26 11.8 14.6 0.22 12.0 2.9 3.3 2 1 2 4 4 3 0 C2HE / C2H2 / C2HC zinc-binding finger FYVE PF01363.21 CDJ80848.1 - 0.29 11.3 10.9 2.2 8.5 4.4 2.3 1 1 1 2 2 2 0 FYVE zinc finger zf-CHCC PF10276.9 CDJ80848.1 - 0.34 11.0 5.3 0.55 10.3 0.4 2.9 3 0 0 3 3 3 0 Zinc-finger domain zf-AN1 PF01428.16 CDJ80848.1 - 0.45 10.7 9.8 4.3 7.6 0.2 3.5 4 0 0 4 4 3 0 AN1-like Zinc finger zf-FCS PF06467.14 CDJ80848.1 - 0.61 10.1 10.0 7.1 6.7 0.2 3.2 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif HypA PF01155.19 CDJ80848.1 - 0.69 9.9 3.3 2.1 8.4 3.3 1.8 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ZZ PF00569.17 CDJ80848.1 - 0.89 9.4 6.8 1.2 9.1 0.1 2.9 3 0 0 3 3 3 0 Zinc finger, ZZ type zf-C2HC_2 PF13913.6 CDJ80848.1 - 1.4 8.9 16.3 1.1 9.2 0.8 3.8 4 0 0 4 4 3 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 CDJ80848.1 - 2 8.1 8.8 2.6 7.7 0.1 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger C1_4 PF07975.12 CDJ80848.1 - 2.8 8.2 9.3 14 6.0 9.1 2.3 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C2H2_7 PF15269.6 CDJ80848.1 - 3.1 7.9 8.5 12 6.1 0.8 3.0 3 0 0 3 3 3 0 Zinc-finger zf-ribbon_3 PF13248.6 CDJ80848.1 - 5.7 6.5 11.7 26 4.4 3.9 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Zf_RING PF16744.5 CDJ80848.1 - 8.6 6.6 7.7 29 4.9 1.5 3.0 1 1 2 3 3 3 0 KIAA1045 RING finger VATC PF18716.1 CDJ80848.1 - 9.9 6.1 10.2 37 4.3 0.1 2.7 2 1 0 2 2 2 0 Vms1-associating treble clef domain PARP PF00644.20 CDJ80849.1 - 4.8e-59 199.3 0.0 9e-59 198.4 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 CDJ80849.1 - 1.4e-42 145.1 1.9 3e-42 144.0 1.9 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain zf-PARP PF00645.18 CDJ80849.1 - 6.9e-29 100.5 5.6 7.2e-17 62.0 0.4 3.6 3 0 0 3 3 3 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region WGR PF05406.15 CDJ80849.1 - 2.9e-22 78.5 0.3 7.8e-22 77.1 0.3 1.8 1 0 0 1 1 1 1 WGR domain PADR1 PF08063.12 CDJ80849.1 - 1.2e-15 57.0 5.2 2.8e-15 55.8 5.2 1.7 1 0 0 1 1 1 1 PADR1 (NUC008) domain JAMP PF05571.12 CDJ80850.1 - 4.8e-83 279.2 22.3 1.2e-82 277.8 22.3 1.7 1 0 0 1 1 1 1 JNK1/MAPK8-associated membrane protein Seipin PF06775.14 CDJ80850.1 - 1.4e-24 87.3 1.9 3.2e-24 86.2 1.9 1.6 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Ninjurin PF04923.12 CDJ80850.1 - 0.16 11.9 0.1 0.16 11.9 0.1 3.8 3 1 1 4 4 4 0 Ninjurin HTH_48 PF17906.1 CDJ80851.1 - 2.6e-16 59.4 1.6 4.9e-16 58.6 1.6 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_Tnp_IS630 PF01710.16 CDJ80851.1 - 1.1e-07 31.9 0.1 1.4e-07 31.5 0.1 1.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 CDJ80851.1 - 2.1e-06 27.9 1.4 4.4e-06 26.8 0.4 1.9 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.6 CDJ80851.1 - 3.1e-06 26.8 0.1 0.017 14.9 0.0 2.4 2 0 0 2 2 2 2 Homeodomain-like domain HTH_38 PF13936.6 CDJ80851.1 - 2.2e-05 24.1 0.0 5.2e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 CDJ80851.1 - 9.3e-05 23.0 0.1 0.00019 22.0 0.0 1.6 2 0 0 2 2 1 1 Homeodomain-like domain HTH_28 PF13518.6 CDJ80851.1 - 0.0001 22.4 0.0 0.51 10.5 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_50 PF18024.1 CDJ80851.1 - 0.00029 20.4 0.0 0.00052 19.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 CDJ80851.1 - 0.0014 18.5 0.1 0.0027 17.6 0.1 1.4 1 0 0 1 1 1 1 HTH domain HTH_29 PF13551.6 CDJ80851.1 - 0.0016 18.5 0.0 0.26 11.4 0.0 2.4 2 1 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_1 PF01527.20 CDJ80851.1 - 0.0032 17.7 0.8 0.77 10.1 0.1 2.3 1 1 1 2 2 2 1 Transposase HTH_40 PF14493.6 CDJ80851.1 - 0.004 17.6 0.1 0.0094 16.4 0.1 1.6 2 0 0 2 2 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 CDJ80851.1 - 0.011 15.1 0.6 0.28 10.6 0.0 3.2 4 1 1 5 5 5 0 Helix-turn-helix domain of transposase family ISL3 HTH_6 PF01418.17 CDJ80851.1 - 0.015 15.2 0.0 0.072 13.1 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family Terminase_5 PF06056.12 CDJ80851.1 - 0.024 14.5 0.1 4.7 7.2 0.0 2.7 3 0 0 3 3 3 0 Putative ATPase subunit of terminase (gpP-like) IF2_N PF04760.15 CDJ80851.1 - 0.028 14.2 0.0 0.068 13.0 0.0 1.6 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region TubC_N PF18563.1 CDJ80851.1 - 0.03 14.3 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 TubC N-terminal docking domain DUF488 PF04343.13 CDJ80851.1 - 0.041 14.5 0.1 0.057 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF488 HTH_5 PF01022.20 CDJ80851.1 - 0.049 13.5 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_10 PF04967.12 CDJ80851.1 - 0.05 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain HTH_36 PF13730.6 CDJ80851.1 - 0.051 13.5 0.0 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_30 PF13556.6 CDJ80851.1 - 0.054 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain GerE PF00196.19 CDJ80851.1 - 0.13 11.9 0.2 0.27 10.8 0.2 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family NUMOD1 PF07453.13 CDJ80851.1 - 0.2 12.0 0.1 0.35 11.2 0.1 1.4 1 0 0 1 1 1 0 NUMOD1 domain CDP-OH_P_transf PF01066.21 CDJ80852.1 - 3.1e-12 47.1 0.1 3.1e-12 47.1 0.1 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase adh_short_C2 PF13561.6 CDJ80853.1 - 9.3e-58 195.5 0.3 1.1e-57 195.3 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDJ80853.1 - 4.7e-44 150.2 0.2 6.4e-44 149.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase MtrA PF04208.14 CDJ80853.1 - 0.017 14.8 0.2 0.073 12.7 0.1 2.0 2 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit A 2-Hacid_dh_C PF02826.19 CDJ80853.1 - 0.076 12.4 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain E1-E2_ATPase PF00122.20 CDJ80854.1 - 1e-41 142.4 2.8 2.9e-41 141.0 2.8 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CDJ80854.1 - 9.6e-35 119.9 0.7 9.6e-35 119.9 0.7 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CDJ80854.1 - 4.1e-22 79.5 0.1 2.9e-18 66.9 0.1 3.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDJ80854.1 - 3e-18 65.7 0.0 5.5e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CDJ80854.1 - 2.1e-13 49.7 0.0 3.7e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CDJ80854.1 - 1.5e-06 28.2 0.9 0.00026 20.8 0.3 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CDJ80854.1 - 0.038 14.4 0.1 0.26 11.7 0.1 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cadherin PF00028.17 CDJ80855.1 - 6e-72 238.2 10.2 4.8e-14 52.6 0.0 8.7 8 0 0 8 8 8 8 Cadherin domain Cadherin_3 PF16184.5 CDJ80855.1 - 4.2e-05 23.5 3.6 1.9 8.5 0.1 5.0 5 0 0 5 5 5 2 Cadherin-like DUF4249 PF14054.6 CDJ80855.1 - 0.00011 21.9 3.2 0.0015 18.2 2.1 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF4249) Cadherin_2 PF08266.12 CDJ80855.1 - 0.026 14.3 0.0 14 5.6 0.0 3.3 3 0 0 3 3 3 0 Cadherin-like Luciferase_N PF05295.11 CDJ80855.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain DUF1072 PF06380.11 CDJ80855.1 - 1.9 8.4 4.2 6.1 6.8 4.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1072) Sugar_tr PF00083.24 CDJ80856.1 - 1.6e-66 225.1 29.8 2e-66 224.8 29.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ80856.1 - 1.5e-16 60.3 62.1 1.5e-15 57.0 34.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CDJ80856.1 - 0.0004 18.9 19.6 0.018 13.5 5.6 2.3 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Fijivirus_P9-2 PF06837.11 CDJ80856.1 - 0.59 9.6 3.5 0.29 10.6 0.5 1.9 2 0 0 2 2 2 0 Fijivirus P9-2 protein AAA_12 PF13087.6 CDJ80857.1 - 6e-37 127.2 0.0 8.9e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ80857.1 - 1e-06 28.7 0.0 2.7e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CDJ80857.1 - 2.6e-06 27.4 0.0 0.00013 21.8 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 CDJ80857.1 - 6.5e-06 26.0 0.2 0.076 12.7 0.6 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CDJ80857.1 - 0.00013 22.3 0.1 0.00068 20.0 0.1 2.1 2 1 0 2 2 2 1 AAA domain UvrD_C PF13361.6 CDJ80857.1 - 0.0046 16.4 0.0 0.046 13.1 0.0 2.1 1 1 1 2 2 2 1 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.14 CDJ80857.1 - 0.012 15.5 0.7 0.39 10.5 0.3 2.3 1 1 0 2 2 2 0 Helicase UvrD_C_2 PF13538.6 CDJ80857.1 - 0.034 14.0 0.0 0.091 12.6 0.0 1.8 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain ResIII PF04851.15 CDJ80857.1 - 0.036 14.1 0.3 0.22 11.5 0.1 2.5 2 2 1 3 3 3 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CDJ80857.1 - 0.12 11.6 0.2 5 6.3 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ApbA PF02558.16 CDJ80857.1 - 0.12 12.0 0.0 0.81 9.3 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA zf-C2H2 PF00096.26 CDJ80858.1 - 2.4e-11 43.4 38.5 5.3e-05 23.4 3.2 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ80858.1 - 3e-09 36.9 11.7 1.2e-06 28.7 2.9 4.8 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDJ80858.1 - 3e-07 30.7 32.1 0.0025 18.5 3.3 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ80858.1 - 0.0005 20.3 12.7 0.017 15.4 0.5 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 CDJ80858.1 - 0.018 15.0 15.5 0.59 10.2 2.1 3.2 2 1 0 2 2 2 0 BED zinc finger zf-met PF12874.7 CDJ80858.1 - 0.086 13.3 1.5 0.086 13.3 1.5 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 CDJ80858.1 - 0.12 13.1 6.1 14 6.5 5.9 2.6 1 1 0 1 1 1 0 zinc-ribbon family zf-C2H2_8 PF15909.5 CDJ80858.1 - 0.28 11.5 10.0 0.66 10.3 9.3 2.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 CDJ80858.1 - 0.53 10.4 22.8 0.48 10.5 3.3 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-MYST PF17772.1 CDJ80858.1 - 0.63 9.7 3.2 7.7 6.2 0.0 3.0 3 0 0 3 3 3 0 MYST family zinc finger domain Vta1 PF04652.16 CDJ80859.1 - 5.4e-44 149.7 0.4 5.4e-44 149.7 0.4 3.3 3 0 0 3 3 3 1 Vta1 like Golgin_A5 PF09787.9 CDJ80859.1 - 7.1e-20 71.7 57.6 3.9e-19 69.2 34.6 3.4 1 1 2 3 3 3 2 Golgin subfamily A member 5 Vta1_C PF18097.1 CDJ80859.1 - 3.2e-11 42.7 0.3 3.2e-11 42.7 0.3 2.5 2 0 0 2 2 2 1 Vta1 C-terminal domain Pox_A_type_inc PF04508.12 CDJ80859.1 - 5.8e-05 22.8 1.9 0.064 13.1 0.1 3.3 2 0 0 2 2 2 2 Viral A-type inclusion protein repeat Bacillus_HBL PF05791.11 CDJ80859.1 - 0.0038 17.1 3.7 0.0038 17.1 3.7 3.8 5 1 1 6 6 6 1 Bacillus haemolytic enterotoxin (HBL) RhoGAP PF00620.27 CDJ80860.1 - 2.5e-24 85.8 0.0 3.9e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain LRR_8 PF13855.6 CDJ80861.1 - 8.2e-51 169.6 20.2 4.7e-13 48.7 0.3 7.1 2 2 5 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 CDJ80861.1 - 1.2e-31 108.3 29.6 1.3e-06 28.6 0.6 9.0 6 3 3 9 9 9 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CDJ80861.1 - 4.7e-17 62.1 0.1 1.3e-08 34.9 0.0 3.5 3 0 0 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 CDJ80861.1 - 7e-16 56.3 26.0 0.041 14.4 0.1 12.4 12 2 1 13 13 12 3 Leucine Rich Repeat LRR_9 PF14580.6 CDJ80861.1 - 2.3e-09 37.0 10.4 0.0011 18.6 0.9 3.9 1 1 2 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 CDJ80861.1 - 1.4e-08 34.1 26.5 0.62 10.3 0.0 11.6 13 0 0 13 13 13 3 Leucine Rich repeat DUF5305 PF17231.2 CDJ80861.1 - 0.00041 19.8 0.1 0.00067 19.1 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5305) TMEM154 PF15102.6 CDJ80861.1 - 0.0087 16.0 1.0 0.019 14.9 1.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family BatD PF13584.6 CDJ80861.1 - 0.034 13.0 0.4 0.063 12.1 0.3 1.4 1 1 1 2 2 2 0 Oxygen tolerance MFS_2 PF13347.6 CDJ80861.1 - 0.04 12.5 0.0 0.053 12.1 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein TMEM51 PF15345.6 CDJ80861.1 - 0.14 11.9 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 Hep_59 PF07052.11 CDJ80863.1 - 2.8e-20 73.0 1.6 2.8e-20 73.0 1.6 2.0 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 DUF1451 PF07295.11 CDJ80863.1 - 7.8 6.5 8.2 9.6 6.2 0.5 2.6 2 1 1 3 3 3 0 Zinc-ribbon containing domain EF-hand_6 PF13405.6 CDJ80864.1 - 0.013 15.4 0.0 0.95 9.6 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain EF-hand_8 PF13833.6 CDJ80864.1 - 0.032 14.1 0.0 0.48 10.3 0.0 2.5 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_7 PF13499.6 CDJ80864.1 - 0.039 14.4 0.0 0.15 12.6 0.0 1.9 2 1 0 2 2 2 0 EF-hand domain pair LIM PF00412.22 CDJ80865.1 - 5.9e-22 77.6 19.8 8.1e-12 45.2 3.1 2.3 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 CDJ80865.1 - 2.3e-19 69.0 5.8 1.2e-18 66.7 5.4 2.2 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CDJ80865.1 - 1.4e-05 24.9 0.2 2.9e-05 23.9 0.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 CDJ80865.1 - 0.0044 16.4 0.1 0.0098 15.3 0.1 1.6 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez DUF2685 PF10886.8 CDJ80865.1 - 0.0089 16.2 0.1 0.0089 16.2 0.1 2.9 3 1 1 4 4 4 1 Protein of unknown function (DUF2685) RVT_1 PF00078.27 CDJ80866.1 - 0.022 14.3 0.0 0.049 13.1 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CDJ80866.1 - 0.051 13.1 0.0 0.18 11.3 0.0 1.7 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family RT_RNaseH PF17917.1 CDJ80866.1 - 0.092 13.0 0.6 0.23 11.8 0.2 1.8 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Exo_endo_phos_2 PF14529.6 CDJ80866.1 - 0.17 11.7 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase DUF621 PF04789.15 CDJ80868.1 - 5.3e-05 22.5 0.4 5.9e-05 22.4 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF621) DUF1794 PF08768.11 CDJ80869.1 - 4.2e-20 72.2 0.0 4.8e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) TIL PF01826.17 CDJ80870.1 - 1.2e-13 51.1 39.7 9.1e-08 32.2 17.1 2.3 2 0 0 2 2 2 2 Trypsin Inhibitor like cysteine rich domain MFS_1 PF07690.16 CDJ80871.1 - 0.098 11.6 10.9 0.15 11.0 10.4 1.5 1 1 0 1 1 1 0 Major Facilitator Superfamily Motile_Sperm PF00635.26 CDJ80872.1 - 0.0068 16.2 0.0 0.0078 16.1 0.0 1.1 1 0 0 1 1 1 1 MSP (Major sperm protein) domain CFTR_R PF14396.6 CDJ80872.1 - 0.22 11.0 0.0 0.25 10.9 0.0 1.0 1 0 0 1 1 1 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain NAP PF00956.18 CDJ80874.1 - 4.5e-30 104.7 8.7 2.7e-25 89.1 1.6 3.1 2 1 1 3 3 3 3 Nucleosome assembly protein (NAP) Cytomega_TRL10 PF06084.11 CDJ80875.1 - 0.24 11.4 0.0 0.25 11.3 0.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Thioredoxin_8 PF13905.6 CDJ80876.1 - 8.9e-28 96.5 0.0 1.2e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CDJ80876.1 - 4e-09 36.4 0.0 5.2e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDJ80876.1 - 1.4e-07 31.3 0.0 1.7e-07 31.1 0.0 1.3 1 1 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 CDJ80876.1 - 2.1e-07 30.9 0.1 2.4e-06 27.5 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 CDJ80876.1 - 1.3e-05 25.6 0.0 1.8e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain SCO1-SenC PF02630.14 CDJ80876.1 - 0.0012 18.8 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_9 PF14595.6 CDJ80876.1 - 0.0021 17.8 0.0 0.0048 16.7 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.6 CDJ80876.1 - 0.012 15.8 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like TraF PF13728.6 CDJ80876.1 - 0.11 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 CDJ80876.1 - 0.12 12.6 0.3 0.54 10.5 0.2 2.1 2 1 0 2 2 2 0 Glutaredoxin Glycos_transf_2 PF00535.26 CDJ80876.1 - 0.16 11.7 0.0 0.34 10.7 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 2 EF-hand_1 PF00036.32 CDJ80877.1 - 8.8e-10 37.4 0.8 0.0008 18.8 0.8 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDJ80877.1 - 8.8e-09 35.7 0.8 0.0041 17.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ80877.1 - 7.2e-08 31.6 0.7 0.0065 15.9 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CDJ80877.1 - 3.8e-07 29.5 3.4 0.012 15.5 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CDJ80877.1 - 7.1e-07 29.0 0.9 0.0024 17.7 0.7 2.2 2 0 0 2 2 2 2 EF-hand domain pair Excalibur PF05901.11 CDJ80877.1 - 1.6 9.4 4.5 8.7 7.1 0.0 2.7 3 0 0 3 3 3 0 Excalibur calcium-binding domain ig PF00047.25 CDJ80878.1 - 2e-09 37.5 0.1 6.3e-06 26.3 0.0 3.2 3 0 0 3 3 3 1 Immunoglobulin domain V-set PF07686.17 CDJ80878.1 - 6e-09 36.0 0.2 0.0029 17.8 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin V-set domain Ig_3 PF13927.6 CDJ80878.1 - 1.4e-08 35.2 0.1 0.00072 20.1 0.0 3.3 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 CDJ80878.1 - 1.8e-07 31.1 0.0 0.00072 19.6 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 CDJ80878.1 - 7e-07 29.5 0.1 1.7e-05 25.1 0.0 2.8 3 0 0 3 3 3 1 Immunoglobulin domain Ig_5 PF16681.5 CDJ80878.1 - 0.0046 17.3 0.0 2.3 8.7 0.0 2.8 2 0 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain FCSD-flav_bind PF09242.11 CDJ80878.1 - 0.011 16.1 0.1 0.035 14.4 0.1 1.9 1 1 0 1 1 1 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding Phasin PF05597.11 CDJ80878.1 - 0.012 15.6 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) YhfH PF14149.6 CDJ80878.1 - 0.088 12.8 0.3 0.21 11.6 0.3 1.6 1 0 0 1 1 1 0 YhfH-like protein zf-dskA_traR PF01258.17 CDJ80878.1 - 0.095 12.7 0.4 0.22 11.5 0.4 1.6 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger Ig_6 PF18452.1 CDJ80878.1 - 0.15 11.6 0.5 1.6 8.3 0.0 2.7 3 0 0 3 3 3 0 Immunoglobulin domain Aminotran_3 PF00202.21 CDJ80879.1 - 3e-86 289.6 0.0 3.7e-86 289.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 CDJ80879.1 - 5.5e-06 25.9 0.0 9.1e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 CDJ80879.1 - 1.1e-05 24.8 0.0 0.0091 15.2 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II PhoPQ_related PF10142.9 CDJ80879.1 - 0.24 10.0 0.0 0.35 9.5 0.0 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein DUF4728 PF15860.5 CDJ80881.1 - 0.00027 21.5 9.1 0.00027 21.5 9.1 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4728) TGF_beta PF00019.20 CDJ80885.1 - 2.3e-22 79.9 1.9 2.6e-22 79.7 0.4 1.9 2 0 0 2 2 2 1 Transforming growth factor beta like domain DAN PF03045.15 CDJ80885.1 - 0.051 13.6 0.5 0.051 13.6 0.5 1.8 2 0 0 2 2 2 0 DAN domain Ran_BP1 PF00638.18 CDJ80885.1 - 0.063 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 RanBP1 domain RhoGEF PF00621.20 CDJ80886.1 - 1.1e-38 133.3 6.3 1.1e-38 133.3 6.3 2.3 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.29 CDJ80886.1 - 1.2e-12 48.3 0.0 7.5e-07 29.6 0.0 2.7 2 0 0 2 2 2 2 PH domain FYVE PF01363.21 CDJ80886.1 - 0.0007 19.7 12.3 0.0007 19.7 12.3 2.4 2 0 0 2 2 2 1 FYVE zinc finger IQ_SEC7_PH PF16453.5 CDJ80886.1 - 0.001 19.1 0.0 0.0029 17.6 0.0 1.8 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.16 CDJ80886.1 - 0.0079 16.4 6.9 0.0079 16.4 6.9 2.7 3 0 0 3 3 3 1 FYVE-type zinc finger HEPN_RES_NTD1 PF18870.1 CDJ80886.1 - 0.017 15.3 0.6 0.044 14.0 0.6 1.6 1 0 0 1 1 1 0 HEPN/RES N-terminal domain 1 C1_1 PF00130.22 CDJ80886.1 - 0.019 14.8 5.9 0.057 13.3 5.9 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PH_16 PF17838.1 CDJ80886.1 - 0.068 13.0 0.1 0.99 9.3 0.0 2.7 2 1 0 2 2 2 0 PH domain Sulfotransfer_4 PF17784.1 CDJ80886.1 - 0.13 12.1 1.1 0.45 10.3 0.3 2.3 3 0 0 3 3 3 0 Sulfotransferase domain PH_13 PF16652.5 CDJ80886.1 - 0.27 11.0 9.6 0.064 13.1 0.3 3.8 3 2 0 3 3 3 0 Pleckstrin homology domain COX14 PF14880.6 CDJ80887.1 - 0.093 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Adeno_E3_CR2 PF02439.15 CDJ80887.1 - 0.12 12.1 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Pkinase PF00069.25 CDJ80888.1 - 2.5e-20 72.9 0.0 2.9e-20 72.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ80888.1 - 2.5e-14 53.2 0.0 2.9e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase T4_baseplate PF12322.8 CDJ80888.1 - 0.0061 16.0 0.2 0.053 13.0 0.2 2.0 2 0 0 2 2 2 1 T4 bacteriophage base plate protein APH PF01636.23 CDJ80888.1 - 0.011 15.7 0.0 0.44 10.4 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 CDJ80888.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fructosamin_kin PF03881.14 CDJ80888.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Mon2_C PF16206.5 CDJ80890.1 - 1e-134 450.6 14.6 4.1e-133 445.3 8.9 4.2 2 1 0 2 2 2 1 C-terminal region of Mon2 protein DCB PF16213.5 CDJ80890.1 - 3.4e-57 193.0 6.2 3.4e-57 193.0 6.2 2.5 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 CDJ80890.1 - 1.8e-44 151.4 7.0 1e-42 145.7 0.0 3.6 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Asn_synthase PF00733.21 CDJ80890.1 - 8.8e-06 25.6 1.1 0.03 14.0 0.0 2.4 1 1 1 2 2 2 2 Asparagine synthase DUF1981 PF09324.10 CDJ80890.1 - 0.00054 19.8 1.0 0.023 14.6 0.0 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) HEAT PF02985.22 CDJ80890.1 - 0.0021 18.2 0.4 3.3 8.2 0.1 4.1 2 0 0 2 2 2 1 HEAT repeat DUF3361 PF11841.8 CDJ80890.1 - 0.014 15.4 0.4 0.082 12.9 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) ST7 PF04184.12 CDJ80891.1 - 2.2e-221 736.0 3.5 4e-221 735.2 3.5 1.4 1 1 0 1 1 1 1 ST7 protein TPR_14 PF13428.6 CDJ80891.1 - 0.00015 22.3 3.1 3.5 8.7 0.2 4.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ80891.1 - 0.00021 21.0 0.2 0.88 9.5 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ80891.1 - 0.0016 18.4 0.2 0.48 10.7 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ80891.1 - 0.0045 17.5 1.6 0.56 10.8 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ80891.1 - 0.012 16.2 0.3 0.093 13.4 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_S18 PF01084.20 CDJ80891.1 - 0.13 12.5 1.3 0.28 11.4 0.5 1.9 2 0 0 2 2 2 0 Ribosomal protein S18 Peptidase_M56 PF05569.11 CDJ80891.1 - 0.17 11.0 2.3 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 BlaR1 peptidase M56 UQ_con PF00179.26 CDJ80892.1 - 3.2e-46 156.5 0.0 3.7e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ80892.1 - 3e-05 23.7 0.0 3.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B JmjC PF02373.22 CDJ80893.1 - 6e-24 84.7 0.1 1.2e-23 83.7 0.1 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CDJ80893.1 - 5.5e-19 68.9 0.7 3.9e-18 66.1 0.7 2.0 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 CDJ80893.1 - 0.02 14.6 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 Cupin domain IMUP PF15761.5 CDJ80893.1 - 0.086 13.5 5.6 0.18 12.5 5.6 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein Cupin_1 PF00190.22 CDJ80893.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Cupin Talin_middle PF09141.10 CDJ80895.1 - 6.3e-47 159.6 0.0 1.1e-46 158.9 0.0 1.4 1 0 0 1 1 1 1 Talin, middle domain FERM_f0 PF16511.5 CDJ80895.1 - 1.7e-24 85.9 0.0 2e-23 82.5 0.0 2.6 2 0 0 2 2 2 1 N-terminal or F0 domain of Talin-head FERM FERM_M PF00373.18 CDJ80895.1 - 3.8e-24 85.4 0.0 8.8e-24 84.2 0.0 1.7 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 CDJ80895.1 - 7.6e-19 67.4 0.2 1.9e-15 56.5 0.0 2.7 2 0 0 2 2 2 2 FERM N-terminal domain IRS PF02174.17 CDJ80895.1 - 0.00014 21.7 0.0 0.00043 20.1 0.0 1.8 1 0 0 1 1 1 1 PTB domain (IRS-1 type) ACBP PF00887.19 CDJ80895.1 - 0.00033 20.8 0.0 0.0009 19.4 0.0 1.8 1 0 0 1 1 1 1 Acyl CoA binding protein RA PF00788.23 CDJ80895.1 - 0.0072 16.9 0.0 2.6 8.8 0.0 2.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain I_LWEQ PF01608.17 CDJ80895.1 - 0.029 14.6 0.0 0.029 14.6 0.0 3.1 3 1 1 4 4 4 0 I/LWEQ domain LRR_8 PF13855.6 CDJ80896.1 - 1.7e-47 159.0 49.1 8.9e-15 54.2 4.7 4.3 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CDJ80896.1 - 1.2e-26 92.3 42.1 4.9e-07 30.0 2.1 5.3 3 2 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDJ80896.1 - 2.3e-19 66.9 25.8 0.028 14.9 0.0 9.3 9 0 0 9 9 9 6 Leucine Rich Repeat LRR_5 PF13306.6 CDJ80896.1 - 1e-13 51.3 0.0 2.5e-08 33.9 0.0 2.2 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 CDJ80896.1 - 4e-10 39.5 16.4 6.6e-06 25.7 4.2 3.2 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 CDJ80896.1 - 0.0017 18.2 35.9 2.4 8.5 0.6 9.0 9 0 0 9 9 9 3 Leucine Rich repeat DUF3557 PF12078.8 CDJ80896.1 - 0.073 13.0 4.7 0.12 12.3 2.3 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF3557) LPAM_1 PF08139.12 CDJ80896.1 - 0.61 10.7 2.2 2.4 8.8 2.2 2.1 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site LRRNT PF01462.18 CDJ80896.1 - 1.5 8.6 4.8 1.6 8.5 1.9 2.4 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Scramblase PF03803.15 CDJ80897.1 - 2.7e-52 177.3 0.0 3.4e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 Scramblase SpoIIIAH PF12685.7 CDJ80898.1 - 0.00058 19.8 0.1 0.00073 19.4 0.1 1.0 1 0 0 1 1 1 1 SpoIIIAH-like protein dCMP_cyt_deam_1 PF00383.23 CDJ80899.1 - 4.4e-21 74.7 0.0 7.1e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 CDJ80899.1 - 2.9e-09 37.2 0.1 5.7e-09 36.3 0.0 1.4 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 CDJ80899.1 - 4.6e-06 26.4 1.0 0.00057 19.5 0.1 2.2 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases DDRGK PF09756.9 CDJ80900.1 - 0.95 9.0 11.8 1.6 8.3 11.8 1.3 1 0 0 1 1 1 0 DDRGK domain CDC45 PF02724.14 CDJ80900.1 - 6.8 4.9 9.8 10 4.3 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Transposase_1 PF01359.18 CDJ80902.1 - 4e-27 93.8 0.4 1.6e-26 91.9 0.4 2.0 2 0 0 2 2 2 1 Transposase (partial DDE domain) HTH_48 PF17906.1 CDJ80902.1 - 1.6e-13 50.5 0.0 4.4e-13 49.1 0.0 1.7 2 0 0 2 2 2 1 HTH domain in Mos1 transposase DDE_3 PF13358.6 CDJ80902.1 - 1.8e-07 31.0 0.1 3e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 CDJ80902.1 - 3.8e-05 24.2 1.3 0.00012 22.6 0.4 2.5 2 1 0 2 2 2 1 Homeodomain-like domain HTH_AsnC-type PF13404.6 CDJ80902.1 - 0.00021 21.1 0.0 0.00054 19.7 0.0 1.7 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_29 PF13551.6 CDJ80902.1 - 0.00027 20.9 0.0 0.00085 19.3 0.0 1.9 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 CDJ80902.1 - 0.0013 19.0 0.1 0.0083 16.3 0.0 2.2 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.6 CDJ80902.1 - 0.0029 17.3 0.7 0.11 12.4 0.1 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_24 PF13412.6 CDJ80902.1 - 0.02 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 CDJ80902.1 - 0.024 14.7 1.8 0.057 13.5 0.5 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain Semialdhyde_dh PF01118.24 CDJ80902.1 - 0.055 13.9 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain HTH_50 PF18024.1 CDJ80902.1 - 0.063 12.9 0.0 0.19 11.3 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 CDJ80902.1 - 0.17 11.9 0.0 0.52 10.3 0.0 1.8 2 0 0 2 2 2 0 HTH domain G-alpha PF00503.20 CDJ80903.1 - 4.4e-124 414.2 5.5 5.1e-124 414.0 5.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDJ80903.1 - 9.4e-18 64.3 2.3 4.2e-13 49.1 0.8 2.9 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ80903.1 - 6e-07 29.1 3.3 0.00011 21.6 1.5 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 CDJ80903.1 - 6.5e-05 23.1 0.6 0.15 12.3 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDJ80903.1 - 0.011 15.4 2.8 0.37 10.4 0.9 2.5 2 0 0 2 2 2 0 Ras family TniB PF05621.11 CDJ80903.1 - 0.015 14.7 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein MMR_HSR1 PF01926.23 CDJ80903.1 - 0.023 14.8 0.1 1 9.5 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 CDJ80903.1 - 0.073 12.8 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain EMP24_GP25L PF01105.24 CDJ80904.1 - 5.8e-13 49.2 0.3 7.3e-13 48.9 0.3 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Rubrerythrin PF02915.17 CDJ80904.1 - 0.03 14.7 0.2 0.046 14.1 0.2 1.3 1 0 0 1 1 1 0 Rubrerythrin AAA_12 PF13087.6 CDJ80907.1 - 2.5e-36 125.2 0.0 4.3e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ80907.1 - 1.4e-07 31.6 0.0 3.1e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ80907.1 - 4.7e-07 29.7 2.7 0.0014 18.4 1.7 2.8 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 CDJ80907.1 - 2e-05 24.5 0.0 0.00044 20.1 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 CDJ80907.1 - 0.00018 21.9 0.1 0.00057 20.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain UvrD_C PF13361.6 CDJ80907.1 - 0.028 13.8 0.0 0.15 11.4 0.0 1.9 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.14 CDJ80907.1 - 0.042 13.7 0.2 0.9 9.4 0.2 2.5 2 0 0 2 2 2 0 Helicase DUF3094 PF11293.8 CDJ80907.1 - 0.088 12.5 0.2 12 5.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) ResIII PF04851.15 CDJ80907.1 - 0.096 12.7 0.1 0.3 11.1 0.1 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 CDJ80907.1 - 0.1 12.4 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain CCDC85 PF10226.9 CDJ80908.1 - 3.2e-43 147.7 19.3 7.8e-43 146.4 19.3 1.7 1 1 0 1 1 1 1 CCDC85 family Exonuc_VII_L PF02601.15 CDJ80908.1 - 0.0068 16.0 6.4 0.0068 16.0 6.4 2.2 1 1 1 2 2 2 1 Exonuclease VII, large subunit Shugoshin_N PF07558.11 CDJ80908.1 - 0.18 11.7 3.6 1 9.3 3.6 2.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region HALZ PF02183.18 CDJ80908.1 - 2.3 8.5 10.7 0.26 11.5 0.2 3.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper Pkinase PF00069.25 CDJ80909.1 - 2e-21 76.6 0.0 2.5e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_C PF00433.24 CDJ80909.1 - 2.8e-11 43.9 0.6 4.9e-11 43.2 0.6 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase_Tyr PF07714.17 CDJ80909.1 - 6e-09 35.6 0.0 8.2e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 CDJ80910.1 - 1.4e-16 60.6 0.0 2.2e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 C2 domain C1_1 PF00130.22 CDJ80910.1 - 1.8e-09 37.4 2.5 3.5e-09 36.4 2.5 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF229 PF02995.17 CDJ80911.1 - 1.7e-109 366.7 0.7 2.1e-109 366.4 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) CAP PF00188.26 CDJ80912.1 - 0.00012 22.9 0.0 0.0087 16.9 0.0 2.2 1 1 0 1 1 1 1 Cysteine-rich secretory protein family DUF5352 PF17303.2 CDJ80913.1 - 4.7e-55 186.0 0.7 5.5e-55 185.8 0.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5352) TSGP1 PF07771.11 CDJ80913.1 - 0.005 17.0 0.1 0.0084 16.3 0.1 1.3 1 0 0 1 1 1 1 Tick salivary peptide group 1 ECH_2 PF16113.5 CDJ80913.1 - 0.046 13.2 0.0 0.052 13.0 0.0 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DUF5352 PF17303.2 CDJ80914.1 - 2.1e-20 73.2 8.0 1.1e-09 38.4 0.1 2.0 1 1 1 2 2 2 2 Family of unknown function (DUF5352) NEL PF14496.6 CDJ80914.1 - 0.054 12.9 0.2 0.054 12.9 0.2 1.1 1 0 0 1 1 1 0 C-terminal novel E3 ligase, LRR-interacting GRAB PF10375.9 CDJ80914.1 - 0.14 12.1 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 GRIP-related Arf-binding domain DUF5352 PF17303.2 CDJ80915.1 - 1.4e-18 67.3 0.1 1.6e-18 67.1 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5352) DUF5352 PF17303.2 CDJ80916.1 - 1.9e-69 232.8 0.3 2.3e-69 232.6 0.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5352) ECH_2 PF16113.5 CDJ80916.1 - 0.05 13.1 0.0 0.065 12.7 0.0 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DUF5352 PF17303.2 CDJ80917.1 - 9.1e-70 233.9 0.2 1.1e-69 233.6 0.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5352) TSGP1 PF07771.11 CDJ80917.1 - 0.055 13.6 0.3 0.055 13.6 0.3 1.9 2 1 1 3 3 3 0 Tick salivary peptide group 1 ECH_2 PF16113.5 CDJ80917.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DUF5352 PF17303.2 CDJ80918.1 - 3.7e-60 202.6 0.7 4.3e-60 202.4 0.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5352) SAM_4 PF18017.1 CDJ80920.1 - 1.9e-13 50.2 0.0 4.1e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CDJ80920.1 - 9.2e-08 32.1 0.0 1.9e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CDJ80920.1 - 1.7e-07 31.6 0.0 3.4e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) F-box-like PF12937.7 CDJ80920.1 - 2.5e-06 27.3 0.3 1.2e-05 25.1 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CDJ80920.1 - 3.9e-05 23.4 1.3 0.00018 21.3 1.3 2.2 1 0 0 1 1 1 1 F-box domain SQHop_cyclase_N PF13249.6 CDJ80920.1 - 0.16 11.1 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Squalene-hopene cyclase N-terminal domain PHO4 PF01384.20 CDJ80921.1 - 1e-47 162.9 12.9 2.6e-29 102.4 10.0 2.1 1 1 1 2 2 2 2 Phosphate transporter family Tail_VII PF17091.5 CDJ80921.1 - 0.53 10.2 4.6 3.4 7.6 1.6 2.9 2 0 0 2 2 2 0 Inovirus G7P protein DUF3010 PF11215.8 CDJ80922.1 - 0.043 14.1 1.4 0.62 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3010) DUF3512 PF12024.8 CDJ80922.1 - 0.17 11.3 7.7 1 8.8 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3512) C2 PF00168.30 CDJ80923.1 - 3.9e-17 62.4 0.0 5.1e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 C2 domain PI3K_C2 PF00792.24 CDJ80923.1 - 0.00014 21.8 0.0 0.00019 21.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DOCK-C2 PF14429.6 CDJ80923.1 - 0.0032 17.3 0.1 0.0032 17.3 0.1 1.2 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DnaI_N PF07319.11 CDJ80923.1 - 0.045 14.4 0.0 0.079 13.6 0.0 1.3 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus Amidohydro_2 PF04909.14 CDJ80924.1 - 2.8e-37 129.1 0.1 3.3e-37 128.9 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase Neur_chan_LBD PF02931.23 CDJ80925.1 - 2.8e-43 147.9 2.0 3.8e-43 147.5 2.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ80925.1 - 3.2e-26 92.9 0.1 7.3e-26 91.7 0.1 1.6 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Amidohydro_2 PF04909.14 CDJ80926.1 - 5.4e-19 69.1 0.0 6e-19 68.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Guanylate_cyc PF00211.20 CDJ80927.1 - 1.7e-116 386.3 1.4 1e-60 204.5 0.1 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 CDJ80927.1 - 7.4e-24 84.6 10.6 2.3e-23 83.0 6.9 2.6 2 0 0 2 2 2 1 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF1053 PF06327.14 CDJ80927.1 - 4.6e-06 27.1 0.2 1e-05 26.0 0.2 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) RT_RNaseH_2 PF17919.1 CDJ80928.1 - 1.1e-34 118.4 0.0 1.9e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ80928.1 - 9.6e-32 109.4 0.0 1.4e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SUFU_C PF12470.8 CDJ80928.1 - 0.076 13.1 0.2 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain SCVP PF17619.2 CDJ80930.1 - 4.7e-08 33.8 0.8 6e-08 33.4 0.8 1.1 1 0 0 1 1 1 1 Secreted clade V proteins Androgen_recep PF02166.16 CDJ80930.1 - 0.16 10.8 0.8 0.21 10.4 0.8 1.1 1 0 0 1 1 1 0 Androgen receptor SCVP PF17619.2 CDJ80931.1 - 1.4e-13 51.4 0.1 1.8e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Secreted clade V proteins TIMELESS PF04821.14 CDJ80932.1 - 4.5e-53 180.3 1.2 1.3e-52 178.8 1.2 1.9 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 CDJ80932.1 - 1.8e-25 90.2 1.6 1.8e-25 90.2 1.6 4.2 3 1 0 4 4 4 2 Timeless protein C terminal region Capsule_synth PF05159.14 CDJ80932.1 - 0.09 12.2 0.1 16 4.9 0.0 2.6 3 0 0 3 3 3 0 Capsule polysaccharide biosynthesis protein WD40 PF00400.32 CDJ80933.1 - 0.00043 21.0 1.5 34 5.5 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.6 CDJ80933.1 - 0.0035 17.8 0.0 1.4 9.5 0.0 3.3 3 0 0 3 3 3 1 PQQ-like domain SAPS PF04499.15 CDJ80933.1 - 0.055 12.3 1.1 0.056 12.2 1.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BBS2_Mid PF14783.6 CDJ80933.1 - 0.11 12.6 0.0 1.3 9.1 0.0 2.7 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region zf-HIT PF04438.16 CDJ80934.1 - 2.5e-08 33.6 12.6 5.1e-08 32.7 12.6 1.5 1 0 0 1 1 1 1 HIT zinc finger HTH_AsnC-type PF13404.6 CDJ80934.1 - 0.066 13.0 0.9 3.1 7.7 0.1 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain zf-HC2 PF13490.6 CDJ80934.1 - 0.22 11.8 0.0 0.22 11.8 0.0 3.6 4 0 0 4 4 4 0 Putative zinc-finger PolC_DP2 PF03833.13 CDJ80934.1 - 0.33 8.8 4.8 0.34 8.7 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-Mss51 PF13824.6 CDJ80934.1 - 6.3 7.0 10.8 13 5.9 10.8 1.6 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Ribosomal_L21p PF00829.21 CDJ80935.1 - 5.4e-15 55.5 0.1 9.4e-15 54.7 0.0 1.4 2 0 0 2 2 2 1 Ribosomal prokaryotic L21 protein CUE PF02845.16 CDJ80936.1 - 4.7e-10 39.0 0.0 9.4e-10 38.0 0.0 1.6 1 0 0 1 1 1 1 CUE domain DMA PF03474.14 CDJ80936.1 - 0.011 15.4 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 DMRTA motif DUF4633 PF15464.6 CDJ80936.1 - 0.19 11.9 5.2 0.33 11.1 2.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4633) CAP PF00188.26 CDJ80937.1 - 2e-15 57.8 5.4 2.8e-15 57.3 5.4 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SSP160 PF06933.11 CDJ80937.1 - 0.0014 16.9 10.2 0.0023 16.2 10.2 1.2 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 bZIP_1 PF00170.21 CDJ80938.1 - 4.2e-06 26.8 17.7 7.4e-06 26.0 17.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CDJ80938.1 - 2.6e-05 24.2 25.8 9.4e-05 22.4 25.8 1.8 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CDJ80938.1 - 0.0017 18.8 12.6 0.003 18.0 12.6 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor AAA_11 PF13086.6 CDJ80938.1 - 0.09 12.5 2.4 0.13 12.0 2.4 1.2 1 0 0 1 1 1 0 AAA domain DUF5320 PF17253.2 CDJ80938.1 - 0.92 10.6 2.7 1.6 9.8 2.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5320) DUF3987 PF13148.6 CDJ80938.1 - 2 7.3 9.2 3.1 6.7 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF1192 PF06698.11 CDJ80938.1 - 3.7 7.7 8.8 1.1 9.4 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) RIBIOP_C PF04950.12 CDJ80938.1 - 6.1 6.2 6.5 9.1 5.6 6.5 1.2 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal HTHP PF11534.8 CDJ80939.1 - 0.14 12.6 0.0 0.19 12.2 0.0 1.2 1 0 0 1 1 1 0 Hexameric tyrosine-coordinated heme protein (HTHP) Amino_oxidase PF01593.24 CDJ80941.1 - 3.2e-12 46.5 0.0 7.2e-12 45.3 0.0 1.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ80941.1 - 0.0016 18.6 0.0 0.0049 17.1 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GLF PF03275.13 CDJ80941.1 - 0.072 12.8 0.1 7.7 6.2 0.0 2.4 2 0 0 2 2 2 0 UDP-galactopyranose mutase DUF4604 PF15377.6 CDJ80942.1 - 1e-06 29.3 18.9 8.8e-06 26.2 18.9 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) DUF5486 PF17588.2 CDJ80942.1 - 0.0051 16.7 0.4 0.013 15.3 0.4 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5486) P66_CC PF16563.5 CDJ80943.1 - 2.2e-11 43.1 7.6 6.3e-11 41.7 7.6 1.8 1 0 0 1 1 1 1 Coiled-coil and interaction region of P66A and P66B with MBD2 ketoacyl-synt PF00109.26 CDJ80944.1 - 0.0061 16.2 3.4 0.0069 16.0 3.4 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Folliculin PF11704.8 CDJ80945.1 - 1.5 8.7 5.4 1.6 8.6 5.4 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Shisa PF13908.6 CDJ80945.1 - 5.9 7.1 6.6 7.3 6.8 6.6 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TetR_C_28 PF17937.1 CDJ80945.1 - 9.2 6.8 11.1 6.2 7.3 0.6 2.2 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain adh_short PF00106.25 CDJ80946.1 - 4.8e-30 104.5 0.0 6.3e-29 100.8 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ80946.1 - 5.1e-19 68.8 0.0 7e-18 65.0 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ80946.1 - 1.2e-05 25.3 0.0 1.9e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDJ80946.1 - 0.014 14.8 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Btz PF09405.10 CDJ80947.1 - 2.4e-06 27.8 6.6 4.5e-06 26.9 5.9 2.0 1 1 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding DUF4187 PF13821.6 CDJ80948.1 - 8e-16 57.6 5.6 1.9e-15 56.4 5.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 CDJ80948.1 - 1.6e-10 40.7 0.2 3.4e-10 39.6 0.2 1.6 1 1 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CDJ80948.1 - 2.1e-05 24.5 0.1 2.1e-05 24.5 0.1 2.0 2 0 0 2 2 2 1 G-patch domain DUF1664 PF07889.12 CDJ80948.1 - 4.4 7.4 5.7 2.9 8.0 2.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3043 PF11241.8 CDJ80948.1 - 8.7 6.3 9.6 0.25 11.4 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) CwfJ_C_1 PF04677.15 CDJ80949.1 - 7.7e-38 129.1 0.0 2.1e-37 127.7 0.0 1.6 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 CDJ80949.1 - 2e-13 51.0 0.0 1e-12 48.8 0.0 2.2 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 Metallophos_3 PF14582.6 CDJ80949.1 - 0.02 14.2 0.0 0.043 13.1 0.0 1.5 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily I-set PF07679.16 CDJ80950.1 - 1.1e-185 602.4 16.6 5.2e-21 74.5 0.0 20.1 19 0 0 19 19 19 19 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ80950.1 - 2e-140 457.7 30.7 1.7e-10 41.3 0.1 20.9 20 0 0 20 20 20 19 Immunoglobulin domain ig PF00047.25 CDJ80950.1 - 1.9e-69 229.9 25.5 1.2e-06 28.6 0.1 18.7 17 1 1 18 18 18 14 Immunoglobulin domain Ig_2 PF13895.6 CDJ80950.1 - 1.3e-66 220.9 31.7 1.2e-05 25.5 0.1 19.2 20 0 0 20 20 20 13 Immunoglobulin domain V-set PF07686.17 CDJ80950.1 - 2.6e-21 75.8 22.8 0.0019 18.4 0.0 15.6 13 6 0 13 13 13 5 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDJ80950.1 - 4.8e-07 29.8 12.8 2.5 8.2 0.0 10.3 11 0 0 11 11 11 1 CD80-like C2-set immunoglobulin domain Lep_receptor_Ig PF06328.11 CDJ80950.1 - 9.5e-06 25.5 4.5 0.11 12.5 0.1 5.9 5 0 0 5 5 5 2 Ig-like C2-type domain Ig_6 PF18452.1 CDJ80950.1 - 0.0015 18.1 2.5 12 5.6 0.0 5.4 6 0 0 6 6 6 1 Immunoglobulin domain C1-set PF07654.15 CDJ80950.1 - 0.0084 16.5 23.2 2 8.9 0.0 10.8 14 0 0 14 14 13 2 Immunoglobulin C1-set domain MOLO1 PF17175.4 CDJ80950.1 - 0.075 13.2 4.0 0.16 12.1 1.4 3.1 2 0 0 2 2 2 0 Modulator of levamisole receptor-1 Adeno_E3_CR1 PF02440.15 CDJ80950.1 - 0.27 11.0 10.8 1 9.2 0.2 5.2 6 0 0 6 6 6 0 Adenovirus E3 region protein CR1 Helitron_like_N PF14214.6 CDJ80951.1 - 1.2e-60 205.0 0.0 2.8e-60 203.8 0.0 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 CDJ80951.1 - 9.6e-32 110.5 0.0 1.4e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CDJ80951.1 - 6.5e-07 29.2 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ80951.1 - 0.0014 18.9 0.0 0.004 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CDJ80951.1 - 0.017 15.1 0.0 0.055 13.5 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NB-ARC PF00931.22 CDJ80951.1 - 0.022 14.0 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 CDJ80951.1 - 0.031 14.7 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 CDJ80951.1 - 0.039 13.0 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AFG1_ATPase PF03969.16 CDJ80951.1 - 0.042 12.7 0.0 0.54 9.1 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase AAA_22 PF13401.6 CDJ80951.1 - 0.073 13.3 0.0 0.23 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CDJ80951.1 - 0.17 11.7 0.0 0.48 10.3 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea CAP PF00188.26 CDJ80952.1 - 1.2e-08 35.8 0.2 1.8e-08 35.3 0.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ80952.1 - 0.00028 21.1 1.0 0.00061 20.1 1.0 1.6 1 1 0 1 1 1 1 Ancylostoma-associated secreted protein related DUF2846 PF11008.8 CDJ80952.1 - 0.043 13.8 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) CAP PF00188.26 CDJ80953.1 - 6e-08 33.6 0.1 1e-07 32.8 0.1 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ80953.1 - 0.00067 19.9 1.1 0.0013 19.0 1.1 1.6 1 1 0 1 1 1 1 Ancylostoma-associated secreted protein related CAP PF00188.26 CDJ80954.1 - 8.6e-10 39.5 0.1 1.2e-09 39.1 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ80954.1 - 0.0015 18.8 0.2 0.0049 17.1 0.2 1.8 1 1 0 1 1 1 1 Ancylostoma-associated secreted protein related DUF1104 PF06518.11 CDJ80955.1 - 2.2 8.7 6.7 1.9 8.9 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1104) GYF PF02213.16 CDJ80956.1 - 0.0051 16.5 0.1 0.011 15.4 0.1 1.7 1 0 0 1 1 1 1 GYF domain zf-C2H2_2 PF12756.7 CDJ80956.1 - 0.0072 16.6 6.4 0.036 14.4 0.4 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.12 CDJ80956.1 - 0.36 11.0 4.4 3.3 7.9 0.5 2.5 2 1 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-met PF12874.7 CDJ80956.1 - 0.36 11.3 4.3 2.1 8.8 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Glyco_hydro_30 PF02055.16 CDJ80957.1 - 2.3e-88 296.5 0.6 2.7e-88 296.3 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 CDJ80957.1 - 0.00026 21.2 2.9 0.00049 20.2 2.9 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain HCV_NS5a_1b PF08301.13 CDJ80957.1 - 0.097 13.2 0.0 0.43 11.2 0.0 2.0 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a domain 1b ADH_N_assoc PF13823.6 CDJ80957.1 - 0.5 10.4 0.1 0.5 10.4 0.1 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated Peptidase_M1_N PF17900.1 CDJ80958.1 - 5.5e-38 131.0 0.0 7.3e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF5011 PF16403.5 CDJ80958.1 - 0.091 12.9 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5011) Peptidase_M1 PF01433.20 CDJ80959.1 - 5.3e-75 251.7 0.6 5.3e-75 251.7 0.6 1.8 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 CDJ80959.1 - 1e-51 176.4 0.4 2.1e-51 175.3 0.4 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CDJ80959.1 - 8.9e-45 153.2 0.0 1.1e-43 149.6 0.0 2.1 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Aminopep PF10023.9 CDJ80959.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 1 0 0 1 1 1 1 Putative aminopeptidase Flagellin_D3 PF08884.11 CDJ80959.1 - 0.12 12.8 1.9 0.3 11.5 0.2 2.4 2 0 0 2 2 2 0 Flagellin D3 domain Peptidase_M1 PF01433.20 CDJ80960.1 - 3.9e-77 258.7 0.0 7.1e-77 257.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 CDJ80960.1 - 7.4e-56 190.0 0.2 7.4e-56 190.0 0.2 2.2 4 0 0 4 4 4 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CDJ80960.1 - 9.4e-46 156.3 0.0 1.6e-45 155.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain CoA_trans PF01144.23 CDJ80961.1 - 1.5e-120 400.5 0.7 7.6e-77 257.6 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 CDJ80961.1 - 9.1e-06 25.7 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.23 CDJ80962.1 - 1.3e-06 28.0 0.0 1.5e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Coenzyme A transferase Alg14 PF08660.11 CDJ80963.1 - 7.2e-57 192.1 0.0 7.9e-57 192.0 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_transf_28 PF03033.20 CDJ80963.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.4 1 1 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain TMEM154 PF15102.6 CDJ80965.1 - 0.0085 16.0 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 CDJ80965.1 - 0.022 15.6 0.0 0.036 15.0 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 CDJ80965.1 - 0.14 12.9 0.5 0.3 11.9 0.5 1.7 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal Transposase_1 PF01359.18 CDJ80966.1 - 4.5e-26 90.5 0.8 8e-26 89.7 0.8 1.4 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_48 PF17906.1 CDJ80966.1 - 1.9e-13 50.3 0.4 3.6e-13 49.4 0.4 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase DDE_3 PF13358.6 CDJ80966.1 - 2.2e-08 34.0 0.1 3.1e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 CDJ80966.1 - 0.031 14.9 0.2 0.74 10.5 0.0 3.3 3 1 1 4 4 4 0 Homeodomain-like domain Kunitz_BPTI PF00014.23 CDJ80967.1 - 2.2e-31 107.8 32.1 5.5e-16 58.5 4.8 3.9 3 0 0 3 3 3 2 Kunitz/Bovine pancreatic trypsin inhibitor domain EGF_CA PF07645.15 CDJ80967.1 - 1.6e-20 73.0 25.7 1.9e-12 47.2 8.6 5.8 4 2 0 4 4 4 2 Calcium-binding EGF domain EGF_3 PF12947.7 CDJ80967.1 - 2e-18 66.3 53.3 7.8e-10 38.8 8.3 5.3 4 1 0 4 4 4 3 EGF domain cEGF PF12662.7 CDJ80967.1 - 5.3e-06 26.3 42.7 0.00021 21.1 5.0 5.7 6 0 0 6 6 6 4 Complement Clr-like EGF-like EGF PF00008.27 CDJ80967.1 - 8e-06 26.1 46.7 0.00012 22.3 4.8 6.3 6 1 0 6 6 6 4 EGF-like domain EGF_MSP1_1 PF12946.7 CDJ80967.1 - 0.00017 21.6 40.9 0.0038 17.2 6.8 4.7 3 1 1 4 4 4 3 MSP1 EGF domain 1 hEGF PF12661.7 CDJ80967.1 - 0.00023 21.7 43.2 0.022 15.4 2.6 6.7 8 0 0 8 8 8 4 Human growth factor-like EGF Hexokinase_2 PF03727.16 CDJ80968.1 - 1.9e-79 266.5 0.2 2.9e-79 265.9 0.2 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CDJ80968.1 - 2.6e-68 229.9 0.0 4.1e-68 229.2 0.0 1.3 1 0 0 1 1 1 1 Hexokinase RVT_1 PF00078.27 CDJ80969.1 - 1.5e-09 37.8 0.0 2.1e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Neur_chan_LBD PF02931.23 CDJ80971.1 - 6e-06 25.9 0.5 0.00017 21.1 0.1 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain DUF1515 PF07439.11 CDJ80971.1 - 0.21 11.6 0.8 0.58 10.2 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Phosphorylase PF00343.20 CDJ80973.1 - 2.7e-291 968.1 0.3 3e-291 967.9 0.3 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase DPCD PF14913.6 CDJ80973.1 - 0.029 13.7 0.1 0.057 12.8 0.1 1.4 1 0 0 1 1 1 0 DPCD protein family Ion_trans_2 PF07885.16 CDJ80975.1 - 4e-24 84.4 26.6 2.6e-13 49.7 4.5 2.9 3 0 0 3 3 3 2 Ion channel DUF3687 PF12459.8 CDJ80975.1 - 0.15 11.6 0.1 0.15 11.6 0.1 2.1 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein CENP-W PF15510.6 CDJ80975.1 - 0.19 11.9 0.2 0.8 10.0 0.0 1.9 2 0 0 2 2 2 0 CENP-W protein FA_desaturase PF00487.24 CDJ80975.1 - 1.2 9.0 4.1 2.3 8.0 0.1 2.5 2 0 0 2 2 2 0 Fatty acid desaturase RVT_1 PF00078.27 CDJ80977.1 - 2.5e-31 108.9 0.0 3.2e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mob1_phocein PF03637.17 CDJ80978.1 - 5.4e-35 120.9 0.7 7.5e-35 120.4 0.7 1.1 1 0 0 1 1 1 1 Mob1/phocein family F-box-like PF12937.7 CDJ80978.1 - 0.12 12.2 0.1 0.51 10.3 0.1 2.1 1 1 1 2 2 2 0 F-box-like Rad51 PF08423.11 CDJ80979.1 - 8.6e-13 48.1 0.1 1.1e-12 47.8 0.1 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 CDJ80979.1 - 0.00018 21.1 0.0 0.00033 20.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CDJ80979.1 - 0.0011 18.4 0.8 0.0068 15.8 0.8 1.9 1 1 0 1 1 1 1 KaiC PduV-EutP PF10662.9 CDJ80979.1 - 0.0076 16.0 0.0 0.075 12.8 0.0 2.1 1 1 1 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 CDJ80979.1 - 0.0089 15.8 0.3 0.032 14.0 0.2 1.9 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 CDJ80979.1 - 0.027 14.7 0.4 0.66 10.2 0.4 2.2 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 CDJ80979.1 - 0.033 14.4 0.1 0.62 10.3 0.0 2.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 CDJ80979.1 - 0.054 12.7 0.3 0.077 12.2 0.3 1.5 1 1 0 1 1 1 0 NB-ARC domain AAA PF00004.29 CDJ80979.1 - 0.059 13.8 0.1 0.17 12.3 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 CDJ80979.1 - 0.14 12.7 0.1 0.19 12.2 0.1 1.6 1 1 0 1 1 1 0 ABC transporter RecA PF00154.21 CDJ80979.1 - 0.15 11.5 0.1 0.6 9.5 0.1 1.8 1 1 0 1 1 1 0 recA bacterial DNA recombination protein baeRF_family3 PF18845.1 CDJ80980.1 - 0.013 15.8 0.2 0.016 15.5 0.2 1.1 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 Ribosomal_L29 PF00831.23 CDJ80980.1 - 0.7 9.9 4.8 0.16 11.9 1.2 1.8 2 0 0 2 2 2 0 Ribosomal L29 protein dNK PF01712.19 CDJ80981.1 - 4e-12 46.4 0.0 5.2e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Deoxynucleoside kinase Zeta_toxin PF06414.12 CDJ80981.1 - 0.0017 17.6 0.0 0.0025 17.1 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin TsaE PF02367.17 CDJ80981.1 - 0.0028 17.7 0.0 0.0041 17.1 0.0 1.2 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 CDJ80981.1 - 0.0074 16.8 0.0 0.011 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ80981.1 - 0.052 13.9 0.0 0.081 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CDJ80981.1 - 0.062 13.6 0.0 0.081 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CDJ80981.1 - 0.073 13.0 0.0 0.37 10.7 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 CDJ80981.1 - 0.077 13.2 0.0 0.097 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CDJ80981.1 - 0.11 11.7 0.0 0.52 9.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Cytidylate_kin2 PF13189.6 CDJ80981.1 - 0.18 12.0 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase-like family Ploopntkinase3 PF18751.1 CDJ80981.1 - 0.19 11.6 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 U1snRNP70_N PF12220.8 CDJ80982.1 - 1.7e-23 83.1 1.2 1.7e-23 83.1 1.2 1.9 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 CDJ80982.1 - 9.9e-17 60.5 0.1 1.7e-16 59.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Integrase_H2C2 PF17921.1 CDJ80983.1 - 1.4e-11 44.3 0.7 2.9e-11 43.3 0.7 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Kazal_1 PF00050.21 CDJ80983.1 - 0.015 15.3 0.1 0.03 14.3 0.1 1.4 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain DUF61 PF01886.16 CDJ80983.1 - 0.06 13.4 0.7 0.84 9.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF61 AMP-binding PF00501.28 CDJ80984.1 - 8.8e-100 334.2 0.0 1.4e-99 333.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ80984.1 - 0.001 20.0 0.2 0.001 20.0 0.2 2.1 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 CDJ80985.1 - 1.8e-21 76.5 36.9 1.4e-19 70.2 22.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily E1_DerP2_DerF2 PF02221.15 CDJ80986.1 - 0.015 15.7 0.1 0.033 14.6 0.1 1.7 1 1 0 1 1 1 0 ML domain Str_synth PF03088.16 CDJ80988.1 - 5.8e-24 84.0 0.0 3.8e-23 81.4 0.0 2.3 2 0 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 CDJ80988.1 - 4.5e-11 42.8 0.0 7.1e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 CDJ80988.1 - 0.047 13.9 0.0 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 Arylesterase Neur_chan_memb PF02932.16 CDJ80989.1 - 5.4 7.0 6.5 6.6 6.7 6.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TRIQK PF15168.6 CDJ80991.1 - 0.067 13.1 0.4 0.086 12.7 0.4 1.2 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family DUF2417 PF10329.9 CDJ80992.1 - 0.07 12.5 0.0 0.083 12.3 0.0 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) CitMHS PF03600.16 CDJ80993.1 - 0.01 15.0 0.8 0.011 14.9 0.8 1.1 1 0 0 1 1 1 0 Citrate transporter Pecanex_C PF05041.15 CDJ80994.1 - 9.3e-111 368.9 0.0 1.7e-110 368.0 0.0 1.4 1 0 0 1 1 1 1 Pecanex protein (C-terminus) Transposase_22 PF02994.14 CDJ80994.1 - 0.021 15.0 0.5 1.1 9.5 0.3 2.5 2 0 0 2 2 2 0 L1 transposable element RBD-like domain TPR_1 PF00515.28 CDJ80995.1 - 4.1e-23 80.2 11.3 2.5e-10 39.7 0.5 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ80995.1 - 1.8e-18 65.1 9.7 9.2e-08 31.6 0.4 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ80995.1 - 3.8e-17 61.7 7.4 1.1e-06 28.2 0.6 3.6 2 1 1 3 3 3 3 TPR repeat SGTA_dimer PF16546.5 CDJ80995.1 - 1.7e-14 53.4 0.4 1.7e-14 53.4 0.4 2.2 2 0 0 2 2 2 1 Homodimerisation domain of SGTA TPR_8 PF13181.6 CDJ80995.1 - 6.9e-11 41.5 9.6 2.8e-06 27.1 0.3 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ80995.1 - 5.8e-10 38.5 3.0 5.9e-05 22.8 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ80995.1 - 2.6e-09 37.3 4.9 1.1e-08 35.2 2.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ80995.1 - 2e-08 34.4 1.7 0.015 16.0 0.1 4.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ80995.1 - 6.9e-08 33.0 7.1 9.2e-05 23.0 2.7 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ80995.1 - 4e-07 30.0 7.6 0.0077 16.5 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ80995.1 - 4.5e-06 27.1 10.0 6.5e-05 23.4 2.1 3.2 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_15 PF13429.6 CDJ80995.1 - 9.8e-06 25.0 1.0 0.003 16.8 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 CDJ80995.1 - 3.4e-05 23.2 4.0 0.14 11.7 0.2 3.3 3 0 0 3 3 3 1 SHNi-TPR TPR_10 PF13374.6 CDJ80995.1 - 0.00065 19.5 6.6 0.031 14.1 0.5 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ80995.1 - 0.017 15.2 5.9 0.29 11.2 0.6 2.8 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 CDJ80995.1 - 0.024 14.7 5.1 0.092 12.9 2.9 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat XPC-binding PF09280.11 CDJ80995.1 - 0.029 14.1 7.1 0.74 9.6 1.6 2.5 2 0 0 2 2 2 0 XPC-binding domain BTAD PF03704.17 CDJ80995.1 - 0.056 13.9 4.5 0.82 10.1 3.3 2.9 2 1 0 2 2 2 0 Bacterial transcriptional activator domain STI1 PF17830.1 CDJ80995.1 - 0.26 11.2 9.0 2.1 8.4 9.0 2.3 1 1 0 1 1 1 0 STI1 domain TPR_6 PF13174.6 CDJ80995.1 - 0.36 11.6 4.7 0.72 10.6 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat GerD PF17898.1 CDJ80995.1 - 0.4 10.6 3.0 0.88 9.5 1.2 2.5 2 1 0 2 2 2 0 Spore germination GerD central core domain MIT PF04212.18 CDJ80995.1 - 0.45 10.6 5.6 3 8.0 0.8 3.1 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain LRR_6 PF13516.6 CDJ80996.1 - 0.00011 21.9 1.0 0.085 13.0 0.0 4.4 5 0 0 5 5 5 1 Leucine Rich repeat Herpes_UL37_2 PF07413.11 CDJ80996.1 - 0.056 12.7 0.0 0.11 11.7 0.0 1.4 2 0 0 2 2 2 0 Betaherpesvirus immediate-early glycoprotein UL37 DUF4971 PF16341.5 CDJ80996.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4971) 7TM_GPCR_Srd PF10317.9 CDJ80998.1 - 9.3e-42 143.2 12.0 1.1e-41 142.9 12.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Srh PF10318.9 CDJ80998.1 - 1.9e-07 30.4 6.8 3e-07 29.8 6.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Srj PF10319.9 CDJ80998.1 - 9.1e-06 25.2 4.9 1.1e-05 25.0 4.3 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Sri PF10327.9 CDJ80998.1 - 1.3e-05 24.6 5.4 2e-05 24.0 5.4 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri 7TM_GPCR_Str PF10326.9 CDJ80998.1 - 3.7e-05 23.2 11.2 6.7e-05 22.4 11.2 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str DUF3671 PF12420.8 CDJ80998.1 - 0.2 11.8 1.9 0.48 10.5 0.1 2.2 1 1 2 3 3 3 0 Protein of unknown function 7TM_GPCR_Srd PF10317.9 CDJ80999.1 - 5.2e-30 104.6 2.5 6.2e-30 104.4 2.5 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Srh PF10318.9 CDJ80999.1 - 1.5e-08 34.0 3.4 1.9e-08 33.7 3.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Srj PF10319.9 CDJ80999.1 - 7.4e-08 32.1 3.5 9e-08 31.8 3.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Sri PF10327.9 CDJ80999.1 - 3.1e-07 29.9 0.6 3.8e-07 29.6 0.6 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri 7TM_GPCR_Str PF10326.9 CDJ80999.1 - 5.4e-06 26.0 3.1 6.2e-06 25.8 3.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str Filament PF00038.21 CDJ81000.1 - 1.8e-16 60.6 40.6 2.9e-16 60.0 40.6 1.3 1 0 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 CDJ81000.1 - 3.5e-09 37.0 0.0 6.1e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Lamin Tail Domain MCC-bdg_PDZ PF10506.9 CDJ81000.1 - 0.0063 16.5 1.1 0.028 14.4 0.4 2.6 1 1 1 2 2 2 1 PDZ domain of MCC-2 bdg protein for Usher syndrome YabA PF06156.13 CDJ81000.1 - 0.01 16.5 18.4 0.013 16.1 2.6 3.9 3 0 0 3 3 3 0 Initiation control protein YabA DUF3219 PF11514.8 CDJ81000.1 - 0.036 14.1 0.4 0.11 12.5 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3219) Myc-LZ PF02344.15 CDJ81000.1 - 1.4 9.1 6.0 25 5.1 0.0 3.7 3 0 0 3 3 3 0 Myc leucine zipper domain APG6_N PF17675.1 CDJ81000.1 - 6.9 7.2 32.2 0.43 11.1 11.2 3.4 2 1 0 3 3 3 0 Apg6 coiled-coil region IER PF05760.12 CDJ81001.1 - 1.4 9.1 12.6 1.6 8.9 12.6 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) FAM70 PF14967.6 CDJ81001.1 - 1.8 8.0 3.4 10 5.5 3.4 1.8 1 1 0 1 1 1 0 FAM70 protein SOSSC PF15925.5 CDJ81001.1 - 2.5 9.4 7.4 1.1 10.6 4.2 1.8 1 1 1 2 2 2 0 SOSS complex subunit C Plasmodium_Vir PF05795.11 CDJ81001.1 - 5.2 6.4 6.4 6.1 6.2 6.4 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SOBP PF15279.6 CDJ81001.1 - 6.5 7.3 8.4 7.7 7.0 8.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein WDCP PF15390.6 CDJ81001.1 - 6.7 5.0 10.4 7.1 4.9 10.4 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family 7tm_1 PF00001.21 CDJ81003.1 - 4e-16 59.1 15.3 4.8e-16 58.9 15.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CDJ81003.1 - 1.7e-06 27.9 13.8 1.7e-06 27.9 13.8 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 CDJ81003.1 - 0.0043 16.8 10.4 0.0094 15.7 10.4 1.7 1 1 0 1 1 1 1 Olfactory receptor DUF2975 PF11188.8 CDJ81003.1 - 0.078 12.9 0.3 0.078 12.9 0.3 3.3 3 2 0 3 3 3 0 Protein of unknown function (DUF2975) RMI2 PF16100.5 CDJ81003.1 - 0.096 12.5 0.1 0.52 10.1 0.2 2.1 2 1 0 2 2 2 0 RecQ-mediated genome instability protein 2 Prok-RING_2 PF14445.6 CDJ81003.1 - 0.62 10.3 3.6 0.77 10.0 0.6 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 2 DUF5373 PF17343.2 CDJ81003.1 - 2.5 7.9 13.5 1.8 8.4 0.2 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5373) DUF2569 PF10754.9 CDJ81003.1 - 3.4 8.1 15.8 1.3 9.4 2.0 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF2569) SK_channel PF03530.14 CDJ81004.1 - 1e-36 125.4 1.2 1e-36 125.4 1.2 2.3 2 0 0 2 2 2 1 Calcium-activated SK potassium channel CaMBD PF02888.16 CDJ81004.1 - 6.6e-30 103.1 4.9 1.4e-29 102.1 4.9 1.6 1 0 0 1 1 1 1 Calmodulin binding domain Ion_trans_2 PF07885.16 CDJ81004.1 - 1.7e-15 56.8 1.1 1.7e-15 56.8 1.1 2.2 2 0 0 2 2 2 1 Ion channel Prefoldin_2 PF01920.20 CDJ81004.1 - 0.019 14.9 0.5 0.055 13.4 0.1 2.0 2 1 0 2 2 2 0 Prefoldin subunit Ntox28 PF15605.6 CDJ81004.1 - 0.029 14.6 0.6 0.064 13.5 0.1 1.8 2 0 0 2 2 2 0 Bacterial toxin 28 Gam PF06064.11 CDJ81004.1 - 0.067 13.4 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 Host-nuclease inhibitor protein Gam Lig_chan PF00060.26 CDJ81004.1 - 0.16 11.8 0.6 0.37 10.6 0.1 2.0 2 0 0 2 2 2 0 Ligand-gated ion channel Methyltransf_11 PF08241.12 CDJ81011.1 - 3.4e-18 66.1 0.1 3.9e-12 46.7 0.0 2.8 3 0 0 3 3 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ81011.1 - 9.8e-17 61.5 0.1 6.2e-12 46.1 0.0 3.4 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_PK PF05891.12 CDJ81011.1 - 2.2e-12 46.9 0.0 1.3e-11 44.5 0.0 2.1 2 0 0 2 2 2 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.6 CDJ81011.1 - 2.8e-12 46.8 0.1 2.7e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ81011.1 - 4e-11 42.9 0.1 9.6e-08 32.0 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ81011.1 - 3.3e-10 40.6 0.0 1.7e-06 28.7 0.0 3.2 3 0 0 3 3 3 2 Methyltransferase domain NodS PF05401.11 CDJ81011.1 - 1.4e-07 31.3 1.7 1.1e-06 28.4 0.0 2.5 3 1 0 3 3 3 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 CDJ81011.1 - 9e-05 21.9 0.1 0.0036 16.7 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 CDJ81011.1 - 0.0008 18.6 0.4 0.73 8.9 0.0 2.4 2 0 0 2 2 2 2 DREV methyltransferase Methyltransf_32 PF13679.6 CDJ81011.1 - 0.0021 18.1 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 CDJ81011.1 - 0.0024 17.6 0.0 0.0086 15.8 0.0 1.9 2 0 0 2 2 2 1 Met-10+ like-protein TehB PF03848.14 CDJ81011.1 - 0.0037 16.7 0.0 0.03 13.7 0.0 2.1 2 0 0 2 2 2 1 Tellurite resistance protein TehB MTS PF05175.14 CDJ81011.1 - 0.0055 16.3 0.0 0.019 14.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain RrnaAD PF00398.20 CDJ81011.1 - 0.009 15.1 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 CDJ81011.1 - 0.018 14.4 0.0 0.041 13.2 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase domain FtsJ PF01728.19 CDJ81011.1 - 0.15 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase p450 PF00067.22 CDJ81012.1 - 2.3e-82 277.2 0.0 3e-82 276.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Lectin_C PF00059.21 CDJ81014.1 - 5.6e-08 33.5 1.0 8.5e-08 32.9 0.6 1.6 2 0 0 2 2 2 1 Lectin C-type domain fn3 PF00041.21 CDJ81015.1 - 0.068 13.5 6.7 2 8.8 0.1 4.3 4 2 0 4 4 4 0 Fibronectin type III domain fn3_4 PF16794.5 CDJ81015.1 - 0.12 12.3 0.1 16 5.5 0.0 2.9 3 0 0 3 3 3 0 Fibronectin-III type domain Romo1 PF10247.9 CDJ81016.1 - 9.5e-23 80.3 16.6 1.4e-22 79.8 16.6 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 CDJ81016.1 - 1.8e-05 25.1 6.1 2.3e-05 24.7 6.1 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Herpes_BLRF2 PF05812.12 CDJ81017.1 - 0.065 13.4 0.4 0.12 12.5 0.1 1.6 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein ShK PF01549.24 CDJ81018.1 - 3.5e-07 30.6 2.7 4.9e-07 30.2 2.7 1.2 1 0 0 1 1 1 1 ShK domain-like PLAC PF08686.11 CDJ81018.1 - 0.0048 17.6 0.3 0.01 16.5 0.3 1.6 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain ShK PF01549.24 CDJ81019.1 - 4.7e-07 30.2 2.7 7e-07 29.7 2.7 1.3 1 0 0 1 1 1 1 ShK domain-like PLAC PF08686.11 CDJ81019.1 - 0.0062 17.3 0.3 0.014 16.2 0.3 1.6 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Aa_trans PF01490.18 CDJ81020.1 - 1.7e-38 132.5 7.9 2.1e-38 132.1 7.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Saf_2TM PF18303.1 CDJ81020.1 - 0.77 9.3 3.3 0.56 9.8 0.1 2.2 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain Aa_trans PF01490.18 CDJ81021.1 - 1.5e-20 73.3 0.2 1.6e-20 73.3 0.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Collagen PF01391.18 CDJ81022.1 - 6.5e-19 67.5 71.1 1.3e-10 40.9 34.8 3.3 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Ion_trans PF00520.31 CDJ81023.1 - 6.5e-116 385.8 33.1 5.1e-66 222.4 16.1 2.1 2 0 0 2 2 2 2 Ion transport protein Ca_chan_IQ PF08763.11 CDJ81023.1 - 5.8e-29 100.1 0.0 1.1e-28 99.2 0.0 1.5 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain GPHH PF16905.5 CDJ81023.1 - 7.1e-29 99.3 0.1 5e-28 96.6 0.1 2.4 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated CAC1F_C PF16885.5 CDJ81023.1 - 0.00019 21.3 0.0 0.46 10.1 0.0 2.2 2 0 0 2 2 2 2 Voltage-gated calcium channel subunit alpha, C-term EF-hand_11 PF08976.11 CDJ81023.1 - 0.091 13.6 0.0 0.22 12.4 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain PKD_channel PF08016.12 CDJ81023.1 - 0.15 10.7 41.3 0.016 13.9 10.2 5.4 4 2 1 5 5 5 0 Polycystin cation channel Tim17 PF02466.19 CDJ81024.1 - 0.0046 17.3 1.7 0.0089 16.4 1.8 1.4 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Phage_holin_5_2 PF16079.5 CDJ81024.1 - 0.13 12.6 0.3 10 6.5 0.3 2.4 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V MarR_2 PF12802.7 CDJ81025.1 - 0.00038 20.3 0.2 0.57 10.1 0.0 2.8 2 0 0 2 2 2 2 MarR family RNA_pol_Rpc34 PF05158.12 CDJ81025.1 - 0.00042 19.8 0.0 0.0095 15.4 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase Rpc34 subunit FWWh PF14922.6 CDJ81025.1 - 0.11 12.5 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function TUDOR PF00567.24 CDJ81027.1 - 7.4e-22 77.6 0.0 5.1e-13 49.1 0.0 2.4 2 0 0 2 2 2 2 Tudor domain Chromo PF00385.24 CDJ81027.1 - 2.7e-05 24.0 0.1 6.9e-05 22.7 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Agenet PF05641.12 CDJ81027.1 - 0.014 15.9 0.0 0.23 12.0 0.0 3.0 3 0 0 3 3 3 0 Agenet domain Myosin_N PF02736.19 CDJ81027.1 - 0.18 11.7 1.8 2.2 8.2 0.1 2.8 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain CDC45 PF02724.14 CDJ81027.1 - 0.64 8.3 6.7 1 7.5 6.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S8 PF00082.22 CDJ81029.1 - 1.1e-53 182.4 2.9 1.5e-53 182.0 2.9 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 CDJ81029.1 - 1.6e-27 95.3 0.2 3.3e-27 94.3 0.2 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 CDJ81029.1 - 4.7e-20 72.2 0.1 1.4e-19 70.7 0.2 1.8 2 0 0 2 2 2 1 Peptidase S8 pro-domain Na_Ala_symp PF01235.17 CDJ81030.1 - 0.0013 18.1 0.3 0.0013 18.1 0.3 1.3 2 0 0 2 2 2 1 Sodium:alanine symporter family DUF973 PF06157.11 CDJ81030.1 - 0.065 12.3 2.6 0.091 11.8 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DOMON PF03351.17 CDJ81031.1 - 3e-07 30.7 0.0 6.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 DOMON domain HATPase_c_3 PF13589.6 CDJ81032.1 - 9.1e-12 45.0 0.0 9.6e-12 44.9 0.0 1.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDJ81032.1 - 2.2e-06 28.1 0.0 2.5e-06 28.0 0.0 1.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Plexin_cytopl PF08337.12 CDJ81033.1 - 5.9e-47 160.6 0.7 7e-47 160.3 0.7 1.0 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain Ground-like PF04155.18 CDJ81035.1 - 7.3e-38 129.1 0.7 2e-14 54.0 0.0 3.3 3 0 0 3 3 3 3 Ground-like domain Hint PF01079.20 CDJ81035.1 - 2.7e-36 125.1 0.0 4.2e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Hint module Hint_2 PF13403.6 CDJ81035.1 - 0.00019 21.8 0.0 0.00042 20.6 0.0 1.6 1 0 0 1 1 1 1 Hint domain Dynein_light PF01221.18 CDJ81035.1 - 0.0035 17.6 0.0 1.6 9.1 0.0 3.0 3 0 0 3 3 3 2 Dynein light chain type 1 DB PF01682.19 CDJ81036.1 - 2.3e-24 85.6 14.7 2.3e-24 85.6 14.7 1.5 2 0 0 2 2 2 1 DB module Arf PF00025.21 CDJ81037.1 - 1.2e-62 210.5 0.3 1.4e-62 210.2 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CDJ81037.1 - 1.7e-15 57.0 0.0 1.9e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ81037.1 - 1.3e-14 54.4 0.0 1.8e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CDJ81037.1 - 2.6e-11 43.3 0.0 3.3e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CDJ81037.1 - 7.1e-08 32.1 0.0 8.5e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDJ81037.1 - 1.5e-06 28.2 0.0 2.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 CDJ81037.1 - 4.4e-05 22.8 0.1 0.0086 15.3 0.0 2.6 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.27 CDJ81037.1 - 0.0036 16.9 0.0 0.036 13.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 CDJ81037.1 - 0.0097 14.9 0.1 0.059 12.3 0.1 1.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 CDJ81037.1 - 0.018 14.5 1.3 0.15 11.6 1.3 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B MENTAL PF10457.9 CDJ81038.1 - 4.8e-48 163.3 4.5 7.8e-48 162.6 4.5 1.3 1 0 0 1 1 1 1 Cholesterol-capturing domain START PF01852.19 CDJ81038.1 - 4.5e-22 78.5 0.8 1e-21 77.3 0.0 1.8 2 0 0 2 2 2 1 START domain zf-Di19 PF05605.12 CDJ81038.1 - 0.0022 18.2 3.4 0.0075 16.5 3.3 2.0 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 CDJ81038.1 - 5.1 8.2 11.1 25 6.1 0.6 4.2 3 0 0 3 3 3 0 C2H2-type zinc finger MBT PF02820.18 CDJ81039.1 - 2e-24 85.7 0.0 8.9e-15 54.8 0.0 2.6 2 0 0 2 2 2 2 mbt repeat SLED PF12140.8 CDJ81039.1 - 3.4e-23 82.3 0.0 9.3e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 SLED domain SAM_1 PF00536.30 CDJ81039.1 - 0.0022 18.4 0.1 0.0076 16.7 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) EF-G-binding_N PF07299.11 CDJ81039.1 - 0.029 14.9 0.1 27 5.4 0.0 3.3 3 0 0 3 3 3 0 Elongation factor G-binding protein, N-terminal zf-C3HC4_2 PF13923.6 CDJ81040.1 - 8e-09 35.2 11.8 8e-09 35.2 11.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ81040.1 - 1.6e-08 34.7 12.6 1.6e-08 34.7 12.6 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CDJ81040.1 - 4.9e-08 32.7 13.2 4.9e-08 32.7 13.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ81040.1 - 1.8e-07 30.9 9.9 1.8e-07 30.9 9.9 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ81040.1 - 3.6e-07 30.1 8.7 3.6e-07 30.1 8.7 1.8 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDJ81040.1 - 2.3e-06 27.7 10.7 2.3e-06 27.7 10.7 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 CDJ81040.1 - 2.4e-06 27.3 1.6 4e-06 26.6 1.6 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 CDJ81040.1 - 8.7e-06 25.6 10.9 1.8e-05 24.6 10.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDJ81040.1 - 0.002 18.0 10.8 0.0043 16.9 10.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 CDJ81040.1 - 0.0051 16.6 7.0 0.0051 16.6 7.0 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 CDJ81040.1 - 0.0053 16.5 7.1 0.014 15.2 7.1 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zinc_ribbon_9 PF14369.6 CDJ81040.1 - 0.006 16.8 2.3 0.023 15.0 2.3 2.1 1 0 0 1 1 1 1 zinc-ribbon Baculo_IE-1 PF05290.11 CDJ81040.1 - 0.015 15.2 2.6 0.023 14.6 2.6 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.7 CDJ81040.1 - 0.038 14.3 12.2 0.038 14.3 12.2 2.3 2 1 0 2 2 2 0 RING-H2 zinc finger domain DZR PF12773.7 CDJ81040.1 - 0.12 12.4 6.7 4.7 7.3 7.8 2.3 1 1 1 2 2 2 0 Double zinc ribbon zf-ANAPC11 PF12861.7 CDJ81040.1 - 0.16 12.0 4.1 0.41 10.7 4.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UDP PF14569.6 CDJ81040.1 - 0.2 11.8 2.6 0.47 10.6 2.6 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_11 PF17123.5 CDJ81040.1 - 2.1 8.2 10.0 1.1 9.0 7.2 2.0 1 1 1 2 2 2 0 RING-like zinc finger KH_1 PF00013.29 CDJ81043.1 - 5.4e-08 32.5 0.1 1.4e-07 31.2 0.1 1.7 1 0 0 1 1 1 1 KH domain Ldl_recept_a PF00057.18 CDJ81045.1 - 3.4e-36 123.2 94.4 2.7e-10 40.3 4.1 6.8 8 0 0 8 8 8 5 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 CDJ81045.1 - 1.2e-10 41.7 0.4 0.00035 21.0 0.0 4.0 4 0 0 4 4 4 3 Low-density lipoprotein receptor repeat class B cEGF PF12662.7 CDJ81045.1 - 3.1e-06 27.0 3.0 3.1e-06 27.0 3.0 5.2 4 0 0 4 4 4 2 Complement Clr-like EGF-like PP2C PF00481.21 CDJ81046.1 - 3.4e-81 272.7 0.0 4.7e-81 272.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CDJ81046.1 - 1.9e-06 27.7 0.0 5e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C Shisa PF13908.6 CDJ81048.1 - 0.19 12.0 5.3 0.16 12.2 4.3 1.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Rrn6 PF10214.9 CDJ81048.1 - 0.94 7.9 3.5 0.97 7.8 3.5 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor YWFCY PF14293.6 CDJ81049.1 - 0.054 13.8 0.6 0.099 13.0 0.6 1.8 1 1 0 1 1 1 0 YWFCY protein Coa1 PF08695.10 CDJ81049.1 - 0.1 12.4 0.0 0.12 12.1 0.0 1.0 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 Myotub-related PF06602.14 CDJ81050.1 - 4e-127 424.0 0.0 5.4e-127 423.5 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FYVE PF01363.21 CDJ81050.1 - 9.1e-08 32.1 15.2 9.2e-08 32.1 12.0 2.6 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 CDJ81050.1 - 0.044 14.0 7.3 0.03 14.5 4.2 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger Y_phosphatase PF00102.27 CDJ81050.1 - 0.086 12.4 0.0 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CDJ81050.1 - 0.091 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family IBR PF01485.21 CDJ81050.1 - 0.093 13.0 5.8 0.21 11.8 3.9 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 CDJ81050.1 - 0.37 11.0 7.3 1.8 8.8 7.3 2.3 1 0 0 1 1 1 0 AN1-like Zinc finger Apyrase PF06079.11 CDJ81051.1 - 8.9e-52 176.1 0.3 1.2e-51 175.7 0.3 1.1 1 0 0 1 1 1 1 Apyrase Amino_oxidase PF01593.24 CDJ81051.1 - 2e-16 60.4 0.0 3e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ81051.1 - 7e-12 45.4 0.1 1.6e-11 44.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SWIRM PF04433.17 CDJ81051.1 - 3.7e-08 33.6 0.1 8.3e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain DAO PF01266.24 CDJ81051.1 - 1.1e-06 28.5 0.4 1.9e-06 27.7 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 CDJ81051.1 - 2.3e-06 28.1 0.0 4.8e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CDJ81051.1 - 9.7e-06 25.0 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 CDJ81051.1 - 1.1e-05 24.8 0.0 1.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CDJ81051.1 - 5.9e-05 22.6 0.0 8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 CDJ81051.1 - 8.4e-05 21.9 0.0 0.00018 20.9 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 CDJ81051.1 - 0.00015 21.0 0.2 0.00021 20.5 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 CDJ81051.1 - 0.00031 19.6 0.2 0.00049 18.9 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 CDJ81051.1 - 0.00046 19.6 0.2 0.00069 19.0 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain MCRA PF06100.11 CDJ81051.1 - 0.02 13.7 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 MCRA family GIDA PF01134.22 CDJ81051.1 - 0.021 13.9 0.2 0.034 13.2 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 CDJ81051.1 - 0.052 12.8 0.0 0.086 12.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CDJ81051.1 - 0.12 11.5 0.2 0.17 10.9 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein zf-CW PF07496.15 CDJ81051.1 - 0.19 11.7 7.3 0.19 11.8 1.7 3.2 3 0 0 3 3 3 0 CW-type Zinc Finger UDPG_MGDP_dh_C PF03720.15 CDJ81052.1 - 1e-14 54.8 0.1 1.1e-14 54.7 0.1 1.1 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain cNMP_binding PF00027.29 CDJ81054.1 - 5.7e-14 52.0 0.0 9.8e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CLZ PF16526.5 CDJ81054.1 - 1.1e-05 25.6 1.6 2.6e-05 24.5 1.6 1.7 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF948 PF06103.11 CDJ81054.1 - 0.031 14.5 0.3 0.53 10.6 0.0 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) YkyA PF10368.9 CDJ81054.1 - 0.069 12.8 0.2 0.12 12.0 0.2 1.4 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein CAP PF00188.26 CDJ81056.1 - 7.4e-17 62.4 3.8 7.4e-17 62.4 3.8 1.9 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Ion_trans PF00520.31 CDJ81056.1 - 2e-10 40.3 15.3 3.4e-10 39.6 15.3 1.3 1 0 0 1 1 1 1 Ion transport protein ASPRs PF17641.2 CDJ81056.1 - 0.0092 16.3 6.1 0.19 12.0 6.1 2.4 1 1 0 1 1 1 1 Ancylostoma-associated secreted protein related Sulfotransfer_1 PF00685.27 CDJ81057.1 - 8.5e-22 77.9 0.0 1e-21 77.7 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CDJ81057.1 - 2.3e-10 41.3 0.1 3.7e-09 37.3 0.1 2.1 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 CDJ81057.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 2 0 0 2 2 2 0 Sulfotransferase family ABC_membrane PF00664.23 CDJ81059.1 - 5.2e-96 321.5 19.0 1.6e-64 218.3 13.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ81059.1 - 1.6e-55 187.3 0.0 3.6e-33 115.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 CDJ81059.1 - 1.5e-09 38.5 0.1 0.0013 19.2 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 CDJ81059.1 - 1.7e-08 34.2 0.9 3.5e-05 23.3 0.2 3.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CDJ81059.1 - 6.6e-08 32.6 0.0 0.015 15.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Rad17 PF03215.15 CDJ81059.1 - 6.6e-06 26.2 0.0 0.013 15.5 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_22 PF13401.6 CDJ81059.1 - 7.2e-06 26.3 0.1 0.02 15.2 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 CDJ81059.1 - 8.4e-06 26.2 0.1 0.13 12.7 0.1 3.3 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDJ81059.1 - 1.6e-05 24.9 0.6 0.23 11.5 0.0 3.5 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 CDJ81059.1 - 1.8e-05 24.1 0.0 0.044 13.1 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin AAA_25 PF13481.6 CDJ81059.1 - 1.9e-05 24.3 0.0 0.29 10.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 CDJ81059.1 - 2e-05 24.3 3.0 0.12 12.2 0.3 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 CDJ81059.1 - 2.7e-05 24.4 0.1 0.18 11.8 0.0 2.6 2 1 0 2 2 2 2 Helicase HerA, central domain AAA_15 PF13175.6 CDJ81059.1 - 4.3e-05 23.4 0.1 0.033 13.9 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 CDJ81059.1 - 4.5e-05 23.3 0.1 0.11 12.2 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein ABC_ATPase PF09818.9 CDJ81059.1 - 0.00019 20.4 0.0 0.00038 19.4 0.0 1.4 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_18 PF13238.6 CDJ81059.1 - 0.00032 21.3 0.0 1.4 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CDJ81059.1 - 0.00033 20.5 0.4 0.27 10.9 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CDJ81059.1 - 0.00037 20.0 0.3 0.2 11.2 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 CDJ81059.1 - 0.00038 20.6 0.0 1.3 9.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.25 CDJ81059.1 - 0.00044 20.0 0.1 0.093 12.4 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 CDJ81059.1 - 0.00091 19.6 0.0 2.6 8.5 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 CDJ81059.1 - 0.00093 19.5 0.2 3.6 7.8 0.2 3.3 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 CDJ81059.1 - 0.001 18.3 0.1 1.2 8.2 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain AAA_21 PF13304.6 CDJ81059.1 - 0.0011 18.9 0.0 1.1 8.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system PRK PF00485.18 CDJ81059.1 - 0.0014 18.4 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.20 CDJ81059.1 - 0.0055 15.9 0.0 1.9 7.6 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_14 PF13173.6 CDJ81059.1 - 0.0057 16.7 0.0 7.8 6.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.13 CDJ81059.1 - 0.0058 15.8 0.0 0.81 8.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 CDJ81059.1 - 0.011 15.8 0.1 1.7 8.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Mg_chelatase PF01078.21 CDJ81059.1 - 0.019 14.4 0.0 3.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 CDJ81059.1 - 0.027 15.0 0.5 9 6.7 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 CDJ81059.1 - 0.034 13.9 0.1 8.2 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CDJ81059.1 - 0.041 13.8 0.1 10 6.0 0.0 2.5 2 0 0 2 2 2 0 NACHT domain SbcCD_C PF13558.6 CDJ81059.1 - 0.047 13.9 0.7 0.36 11.1 0.7 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.7 CDJ81059.1 - 0.048 12.6 0.4 0.91 8.4 0.1 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.6 CDJ81059.1 - 0.055 13.9 0.1 5.4 7.4 0.0 3.0 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.22 CDJ81059.1 - 0.059 13.0 0.0 12 5.5 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain APS_kinase PF01583.20 CDJ81059.1 - 0.083 12.8 0.0 12 5.8 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase NTPase_1 PF03266.15 CDJ81059.1 - 0.099 12.5 0.1 11 6.0 0.0 2.5 2 0 0 2 2 2 0 NTPase TsaE PF02367.17 CDJ81059.1 - 0.11 12.5 0.1 12 5.9 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rotamase_3 PF13616.6 CDJ81060.1 - 4.4e-17 62.7 0.0 1.2e-16 61.3 0.0 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 CDJ81060.1 - 6e-13 49.6 0.0 9.5e-13 48.9 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain G-patch_2 PF12656.7 CDJ81062.1 - 2.8e-15 56.2 0.1 2.8e-15 56.2 0.1 2.4 2 0 0 2 2 2 1 G-patch domain KOW PF00467.29 CDJ81062.1 - 4.8e-11 42.2 1.3 5e-05 23.1 0.1 2.8 2 0 0 2 2 2 2 KOW motif KN17_SH3 PF18131.1 CDJ81062.1 - 0.0019 18.3 2.6 0.0033 17.5 0.5 2.6 3 0 0 3 3 3 1 KN17 SH3-like C-terminal domain G-patch PF01585.23 CDJ81062.1 - 0.0025 17.7 2.0 0.003 17.4 0.2 2.0 2 0 0 2 2 2 1 G-patch domain EVC2_like PF12297.8 CDJ81063.1 - 0.015 14.0 0.8 0.019 13.6 0.8 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein DRY_EERY PF09750.9 CDJ81063.1 - 0.28 11.4 3.1 10 6.4 0.0 2.2 2 0 0 2 2 2 0 Alternative splicing regulator ATP12 PF07542.11 CDJ81064.1 - 6.2e-19 68.4 0.0 1.1e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein HlyIII PF03006.20 CDJ81065.1 - 0.025 14.3 0.3 0.028 14.1 0.3 1.1 1 0 0 1 1 1 0 Haemolysin-III related DUF1180 PF06679.12 CDJ81066.1 - 0.00098 19.6 0.0 0.0012 19.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Orthoreo_P10 PF07204.11 CDJ81066.1 - 0.0035 17.3 0.2 0.0046 16.9 0.2 1.2 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 UL41A PF17591.2 CDJ81066.1 - 0.024 14.7 0.1 0.031 14.4 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL41A EphA2_TM PF14575.6 CDJ81066.1 - 0.043 14.7 0.0 0.051 14.5 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM52 PF14979.6 CDJ81066.1 - 0.079 12.9 0.6 0.11 12.4 0.6 1.2 1 0 0 1 1 1 0 Transmembrane 52 Ly-6_related PF06579.12 CDJ81067.1 - 1.1e-38 132.2 3.5 1.5e-38 131.8 3.5 1.2 1 0 0 1 1 1 1 Caenorhabditis elegans ly-6-related protein TPR_4 PF07721.14 CDJ81068.1 - 0.0055 17.2 2.8 11 7.0 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ81068.1 - 0.0093 16.0 10.7 2 8.7 0.2 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ81068.1 - 0.2 12.3 1.6 81 4.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ81068.1 - 0.47 10.4 9.3 11 6.0 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ81069.1 - 0.00026 21.5 0.7 1.6 9.7 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 CDJ81069.1 - 0.01 15.1 0.2 0.021 14.1 0.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ81069.1 - 0.014 15.5 11.3 2 8.7 0.8 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ81069.1 - 0.015 15.5 3.0 0.61 10.4 0.0 3.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TF_AP-2 PF03299.14 CDJ81069.1 - 0.038 14.0 0.6 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 Transcription factor AP-2 TPR_4 PF07721.14 CDJ81069.1 - 0.045 14.4 0.3 3.5 8.5 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ81069.1 - 0.046 14.4 0.0 1.1 10.0 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Sulfotransfer_2 PF03567.14 CDJ81070.1 - 5.6e-23 82.1 7.3 6.3e-23 82.0 7.3 1.0 1 0 0 1 1 1 1 Sulfotransferase family KIX_2 PF16987.5 CDJ81070.1 - 0.0019 18.2 0.5 0.0088 16.0 0.1 2.2 2 0 0 2 2 2 1 KIX domain Tudor_2 PF18104.1 CDJ81070.1 - 0.7 9.6 3.4 15 5.4 0.1 2.9 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain Glyco_hydro_67N PF03648.14 CDJ81071.1 - 0.0049 17.1 6.8 0.051 13.8 0.9 2.6 1 1 1 2 2 2 2 Glycosyl hydrolase family 67 N-terminus IFT20 PF14931.6 CDJ81071.1 - 0.0067 16.6 12.9 0.35 11.0 2.1 2.6 2 0 0 2 2 2 2 Intraflagellar transport complex B, subunit 20 P4Ha_N PF08336.11 CDJ81071.1 - 0.014 15.4 10.8 0.4 10.7 1.2 2.8 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DivIC PF04977.15 CDJ81071.1 - 0.08 12.7 11.0 1.6 8.5 3.4 2.5 2 0 0 2 2 2 0 Septum formation initiator ORF6C PF10552.9 CDJ81071.1 - 0.085 12.9 4.4 3.8 7.6 0.4 2.5 2 0 0 2 2 2 0 ORF6C domain DUF5446 PF17522.2 CDJ81071.1 - 0.2 11.9 8.0 4.7 7.5 0.6 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5446) BLOC1_2 PF10046.9 CDJ81071.1 - 0.23 11.8 10.2 0.59 10.5 2.4 2.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 CDJ81071.1 - 0.25 11.8 4.8 3.6 8.1 0.9 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 CDJ81071.1 - 0.32 11.6 11.8 5.4 7.7 0.8 3.1 2 0 0 2 2 2 0 SlyX ADIP PF11559.8 CDJ81071.1 - 0.35 11.0 16.9 1.1 9.3 3.1 2.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding HalX PF08663.10 CDJ81071.1 - 1.1 9.7 13.9 7.3 7.0 1.6 3.1 3 0 0 3 3 3 0 HalX domain TSC22 PF01166.18 CDJ81071.1 - 1.4 9.3 7.4 2.6 8.4 2.3 2.8 2 0 0 2 2 2 0 TSC-22/dip/bun family Prominin PF05478.11 CDJ81071.1 - 2.8 5.8 5.5 4.7 5.0 5.5 1.3 1 0 0 1 1 1 0 Prominin XhlA PF10779.9 CDJ81071.1 - 3.2 8.0 7.2 8 6.7 2.6 2.7 2 0 0 2 2 2 0 Haemolysin XhlA ABC_tran_CTD PF16326.5 CDJ81071.1 - 3.3 8.0 14.9 4.7 7.5 0.5 3.1 3 0 0 3 3 3 0 ABC transporter C-terminal domain LapA_dom PF06305.11 CDJ81071.1 - 8.4 6.3 8.9 23 4.9 1.2 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Pox_A_type_inc PF04508.12 CDJ81071.1 - 8.8 6.4 8.0 28 4.8 1.0 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF4407 PF14362.6 CDJ81071.1 - 9 5.6 19.1 0.73 9.1 14.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 CDJ81071.1 - 9.7 5.0 25.9 1.3 7.8 19.2 2.4 1 1 2 3 3 3 0 Spc7 kinetochore protein RVT_1 PF00078.27 CDJ81072.1 - 5e-08 32.7 0.0 6.8e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myotub-related PF06602.14 CDJ81074.1 - 2.1e-14 53.3 0.0 5.7e-13 48.5 0.0 2.2 2 0 0 2 2 2 2 Myotubularin-like phosphatase domain GRAM PF02893.20 CDJ81074.1 - 9e-12 44.9 0.0 1.1e-10 41.4 0.0 2.2 1 1 0 1 1 1 1 GRAM domain ADAM_CR_2 PF17771.1 CDJ81075.1 - 2.2e-20 72.9 2.1 2.2e-20 72.9 2.1 2.0 2 0 0 2 2 2 1 ADAM cysteine-rich domain Reprolysin PF01421.19 CDJ81075.1 - 5.3e-14 52.6 0.0 1.3e-13 51.3 0.0 1.6 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 CDJ81075.1 - 2.4e-11 44.2 0.0 4.5e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CDJ81075.1 - 5.5e-05 23.7 0.0 9.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 CDJ81075.1 - 0.0028 17.3 0.1 0.0047 16.5 0.1 1.3 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_2 PF13574.6 CDJ81075.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CDJ81075.1 - 0.19 11.4 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Salp15 PF12115.8 CDJ81076.1 - 1.2e-05 25.7 1.8 1.4e-05 25.5 1.8 1.1 1 0 0 1 1 1 1 Salivary protein of 15kDa inhibits CD4+ T cell activation ADAM_CR_2 PF17771.1 CDJ81076.1 - 0.00021 21.8 2.6 0.00038 20.9 2.6 1.5 1 1 0 1 1 1 1 ADAM cysteine-rich domain Egg_lysin PF01303.17 CDJ81076.1 - 0.12 12.6 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Egg lysin (Sperm-lysin) TSP_1 PF00090.19 CDJ81078.1 - 2.6e-53 178.0 98.4 5.5e-11 42.5 7.8 6.3 6 0 0 6 6 6 6 Thrombospondin type 1 domain Fib_alpha PF08702.10 CDJ81079.1 - 0.071 13.3 1.8 0.26 11.5 0.2 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family RVT_1 PF00078.27 CDJ81081.1 - 1.9e-16 60.3 0.0 3.8e-16 59.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Oxidored_molyb PF00174.19 CDJ81081.1 - 0.16 11.5 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Oxidoreductase molybdopterin binding domain WBP-1 PF11669.8 CDJ81084.1 - 0.0061 17.2 0.1 0.017 15.8 0.0 1.8 2 0 0 2 2 2 1 WW domain-binding protein 1 DUF3377 PF11857.8 CDJ81084.1 - 0.039 13.9 0.2 0.082 12.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF3487 PF11990.8 CDJ81084.1 - 0.053 13.4 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) TMEM154 PF15102.6 CDJ81084.1 - 0.1 12.5 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF2207 PF09972.9 CDJ81084.1 - 0.11 11.3 0.2 0.15 10.8 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4381 PF14316.6 CDJ81084.1 - 0.15 12.3 0.3 0.26 11.5 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF3880 PF12996.7 CDJ81084.1 - 0.16 12.1 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) CX PF01705.19 CDJ81084.1 - 0.16 12.5 4.5 0.26 11.8 4.5 1.3 1 0 0 1 1 1 0 CX module Gram_pos_anchor PF00746.21 CDJ81084.1 - 0.25 11.3 1.9 0.47 10.4 1.9 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif hNIFK_binding PF12196.8 CDJ81085.1 - 0.02 14.3 0.1 0.055 13.0 0.1 1.7 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK Aldo_ket_red PF00248.21 CDJ81086.1 - 4e-37 128.0 0.0 5.1e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ETX_MTX2 PF03318.13 CDJ81089.1 - 0.0032 17.3 9.4 0.0032 17.3 9.4 2.5 2 1 0 2 2 2 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 RVT_1 PF00078.27 CDJ81091.1 - 6.1e-33 114.2 0.0 7.5e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.26 CDJ81092.1 - 0.00031 21.0 0.9 0.00093 19.5 0.4 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ81092.1 - 0.0054 17.5 0.5 0.016 16.0 0.5 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 CDJ81092.1 - 0.09 12.9 0.2 0.12 12.5 0.2 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger FapA PF03961.13 CDJ81093.1 - 0.03 12.9 0.3 0.034 12.7 0.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 CDJ81093.1 - 0.031 14.5 2.1 0.051 13.8 1.7 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family EST1 PF10374.9 CDJ81093.1 - 0.12 13.0 1.6 1.4 9.6 1.4 2.2 1 1 0 1 1 1 0 Telomerase activating protein Est1 PspA_IM30 PF04012.12 CDJ81093.1 - 0.13 11.8 6.3 0.3 10.7 6.3 1.7 1 1 0 1 1 1 0 PspA/IM30 family Syntaxin-6_N PF09177.11 CDJ81093.1 - 0.29 11.7 5.2 2.1 8.9 5.1 2.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal V_ATPase_I PF01496.19 CDJ81093.1 - 0.59 8.0 3.3 0.74 7.7 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF641 PF04859.12 CDJ81093.1 - 1.1 9.6 6.3 0.63 10.4 3.6 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) FUSC PF04632.12 CDJ81093.1 - 2.1 6.8 3.7 2.4 6.6 3.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family NAPRTase_C PF17956.1 CDJ81094.1 - 5.7e-40 136.2 0.1 1e-39 135.3 0.1 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase_N PF17767.1 CDJ81094.1 - 2.8e-37 127.9 0.0 7.7e-37 126.5 0.0 1.8 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase PF04095.16 CDJ81094.1 - 3.2e-10 40.0 0.0 4.7e-08 32.9 0.0 2.2 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family QRPTase_N PF02749.16 CDJ81094.1 - 0.072 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain zf-C2H2_jaz PF12171.8 CDJ81095.1 - 0.00024 21.3 0.9 0.14 12.5 0.0 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDJ81095.1 - 0.047 14.1 6.0 0.21 12.1 0.2 3.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 CDJ81095.1 - 0.064 13.1 2.4 6.1 6.8 0.3 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_4 PF13894.6 CDJ81095.1 - 0.18 12.7 3.9 8.2 7.6 0.1 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger WH1 PF00568.23 CDJ81096.1 - 1e-15 57.6 0.0 1.5e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 CDJ81096.1 - 3.1e-15 55.4 0.3 1.9e-06 27.5 0.0 2.5 2 0 0 2 2 2 2 WH2 motif PBD PF00786.28 CDJ81096.1 - 6.3e-12 45.7 0.2 1.3e-11 44.6 0.2 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain VHS PF00790.19 CDJ81097.1 - 3e-44 150.3 0.1 3e-44 150.3 0.1 2.3 3 0 0 3 3 3 1 VHS domain Hrs_helical PF12210.8 CDJ81097.1 - 6.5e-32 109.9 1.6 6.5e-32 109.9 1.6 2.1 1 1 0 1 1 1 1 Hepatocyte growth factor-regulated tyrosine kinase substrate FYVE PF01363.21 CDJ81097.1 - 8.2e-19 67.5 9.1 2e-18 66.3 9.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CDJ81097.1 - 0.0037 17.5 5.8 0.0037 17.5 5.8 2.8 2 0 0 2 2 2 1 FYVE-type zinc finger DZR PF12773.7 CDJ81097.1 - 0.96 9.5 9.4 17 5.6 6.9 3.0 2 1 0 2 2 2 0 Double zinc ribbon UIM PF02809.20 CDJ81097.1 - 1.1 9.3 8.8 0.12 12.4 3.6 2.3 2 0 0 2 2 2 0 Ubiquitin interaction motif zf-RING_5 PF14634.6 CDJ81097.1 - 8.6 6.4 15.0 9.4 6.3 11.3 2.5 2 1 0 2 2 2 0 zinc-RING finger domain XTBD PF11952.8 CDJ81098.1 - 0.073 12.8 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 XRN-Two Binding Domain, XTBD DUF4071 PF13281.6 CDJ81099.1 - 6e-123 410.5 3.7 6e-123 410.5 3.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4071) Pkinase PF00069.25 CDJ81099.1 - 2.9e-63 213.7 0.0 9.9e-63 212.0 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ81099.1 - 7.4e-46 156.5 0.0 2.1e-45 155.0 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ81099.1 - 0.00019 20.4 0.2 0.0011 17.9 0.0 2.4 4 0 0 4 4 4 1 Fungal protein kinase TPR_8 PF13181.6 CDJ81099.1 - 0.64 10.4 2.5 0.98 9.8 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Thioredoxin PF00085.20 CDJ81100.1 - 4.9e-27 93.9 0.0 5.8e-27 93.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 CDJ81100.1 - 6.6e-06 25.9 0.1 7.9e-06 25.7 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 CDJ81100.1 - 0.00016 21.6 0.0 0.00018 21.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 CDJ81100.1 - 0.00018 21.0 0.0 0.00018 21.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CDJ81100.1 - 0.00021 21.4 0.0 0.00037 20.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like HyaE PF07449.11 CDJ81100.1 - 0.00032 20.6 0.1 0.00065 19.6 0.1 1.6 1 1 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 CDJ81100.1 - 0.00033 20.9 0.1 0.0014 18.9 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CDJ81100.1 - 0.00074 19.9 0.2 0.003 18.0 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Phosducin PF02114.16 CDJ81100.1 - 0.0055 15.7 0.0 0.0063 15.5 0.0 1.0 1 0 0 1 1 1 1 Phosducin Redoxin PF08534.10 CDJ81100.1 - 0.0055 16.4 0.0 0.0064 16.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin TraF PF13728.6 CDJ81100.1 - 0.046 13.5 0.0 0.059 13.2 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Spectrin PF00435.21 CDJ81101.1 - 1.8e-227 738.7 132.7 6e-24 84.6 8.7 12.2 12 0 0 12 12 12 11 Spectrin repeat EFhand_Ca_insen PF08726.10 CDJ81101.1 - 1.7e-26 92.1 1.2 2e-24 85.4 0.2 3.4 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_1 PF00036.32 CDJ81101.1 - 1.4e-09 36.8 1.1 0.00038 19.8 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CDJ81101.1 - 6e-08 33.0 4.5 8.7e-08 32.5 0.1 3.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ81101.1 - 2e-07 30.4 0.6 0.012 15.5 0.1 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 CDJ81101.1 - 0.001 18.9 0.2 0.056 13.3 0.0 3.1 1 1 1 2 2 2 1 EF-hand domain pair Cytochrom_B562 PF07361.11 CDJ81101.1 - 0.0092 16.6 0.5 0.0092 16.6 0.5 7.3 6 1 1 7 7 7 1 Cytochrome b562 COG2 PF06148.11 CDJ81101.1 - 0.012 15.7 0.6 0.012 15.7 0.6 7.7 6 2 4 10 10 10 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF5616 PF18481.1 CDJ81101.1 - 0.023 15.0 3.3 40 4.5 0.0 5.0 5 0 0 5 5 5 0 Domain of unknown function (DUF5616) Anthrax_toxA PF03497.16 CDJ81101.1 - 0.032 14.4 1.4 3.5 7.7 0.0 2.8 2 0 0 2 2 2 0 Anthrax toxin LF subunit TB2_DP1_HVA22 PF03134.19 CDJ81104.1 - 0.00074 19.4 0.1 0.0014 18.5 0.1 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family PAN_1 PF00024.26 CDJ81108.1 - 1e-39 134.4 35.7 1.3e-14 53.9 5.4 4.4 4 0 0 4 4 4 4 PAN domain PAN_3 PF08277.12 CDJ81108.1 - 0.0045 16.8 0.2 0.0045 16.8 0.2 5.0 5 1 0 5 5 5 2 PAN-like domain PAN_4 PF14295.6 CDJ81108.1 - 9.2 6.3 19.8 0.56 10.2 0.1 4.7 4 1 0 4 4 4 0 PAN domain MAP17 PF15807.5 CDJ81109.1 - 0.021 15.1 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Patched PF02460.18 CDJ81110.1 - 8.2e-112 374.8 14.1 8.2e-64 216.0 4.5 2.1 1 1 1 2 2 2 2 Patched family DUF273 PF03314.14 CDJ81110.1 - 1.5e-58 197.9 1.2 2.7e-58 197.1 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Sterol-sensing PF12349.8 CDJ81110.1 - 4.1e-26 91.7 0.3 4.1e-26 91.7 0.3 2.1 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation SecD_SecF PF02355.16 CDJ81110.1 - 0.039 13.3 12.4 0.097 12.0 3.4 2.4 2 0 0 2 2 2 0 Protein export membrane protein Glyco_transf_34 PF05637.12 CDJ81110.1 - 0.048 13.4 2.1 0.054 13.2 0.3 2.0 2 1 0 2 2 2 0 galactosyl transferase GMA12/MNN10 family Anp1 PF03452.14 CDJ81110.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Anp1 Vma12 PF11712.8 CDJ81110.1 - 0.57 10.2 2.1 11 6.0 0.2 2.6 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase LIM PF00412.22 CDJ81111.1 - 1.8e-09 37.7 2.8 3.4e-09 36.8 2.8 1.5 1 0 0 1 1 1 1 LIM domain PDZ_6 PF17820.1 CDJ81111.1 - 2e-08 33.9 0.0 4e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CDJ81111.1 - 2e-06 28.0 0.0 4.8e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ81111.1 - 3.7e-06 27.2 0.0 9.4e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain DUF2271 PF10029.9 CDJ81111.1 - 0.041 13.5 0.6 0.093 12.4 0.6 1.5 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) Cadherin PF00028.17 CDJ81112.1 - 0.006 17.0 0.0 0.0076 16.7 0.0 1.2 1 0 0 1 1 1 1 Cadherin domain TauE PF01925.19 CDJ81113.1 - 1e-18 67.9 18.3 1.5e-18 67.3 18.3 1.2 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE CPP1-like PF11833.8 CDJ81113.1 - 0.093 12.4 4.0 0.049 13.3 0.7 2.0 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like TauE PF01925.19 CDJ81114.1 - 1.2e-16 61.1 20.1 1.2e-16 61.1 20.1 1.8 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE DUF35_N PF12172.8 CDJ81115.1 - 2 8.4 13.2 2.4 8.1 1.9 2.9 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) KH_1 PF00013.29 CDJ81116.1 - 5.6e-07 29.3 0.4 1.5e-06 27.9 0.4 1.8 1 1 0 1 1 1 1 KH domain LysR_substrate PF03466.20 CDJ81117.1 - 0.0042 16.5 0.0 2 7.8 0.0 2.2 2 0 0 2 2 2 2 LysR substrate binding domain TcpQ PF10671.9 CDJ81117.1 - 0.023 14.8 0.9 6.7 6.9 0.1 2.4 2 0 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q ArgoMid PF16487.5 CDJ81117.1 - 0.11 12.8 0.6 5.8 7.3 0.1 2.5 2 0 0 2 2 2 0 Mid domain of argonaute Peptidase_A17 PF05380.13 CDJ81118.1 - 1.8e-40 138.6 0.1 4.7e-40 137.2 0.1 1.7 1 0 0 1 1 1 1 Pao retrotransposon peptidase RVT_1 PF00078.27 CDJ81118.1 - 4.2e-07 29.7 0.0 9e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RESP18 PF14948.6 CDJ81118.1 - 0.11 12.8 0.0 0.36 11.2 0.0 1.8 1 0 0 1 1 1 0 RESP18 domain DUF218 PF02698.17 CDJ81119.1 - 0.09 12.8 0.7 0.17 11.9 0.7 1.5 1 0 0 1 1 1 0 DUF218 domain HTH_40 PF14493.6 CDJ81119.1 - 0.093 13.2 0.8 0.24 11.9 0.1 2.2 2 1 0 2 2 2 0 Helix-turn-helix domain HMG-CoA_red PF00368.18 CDJ81121.1 - 2.1e-137 458.0 0.9 2.9e-137 457.6 0.9 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase TMF_DNA_bd PF12329.8 CDJ81122.1 - 1.4 9.0 15.5 0.041 13.9 5.4 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding HMMR_C PF15908.5 CDJ81122.1 - 4.3 7.6 8.6 4.5 7.5 7.0 1.8 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Nup54 PF13874.6 CDJ81122.1 - 4.9 7.3 11.2 4.1 7.5 8.4 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 ZapB PF06005.12 CDJ81122.1 - 8.1 7.0 14.6 9.7e+02 0.3 14.6 3.1 1 1 0 1 1 1 0 Cell division protein ZapB Pkinase PF00069.25 CDJ81123.1 - 4.8e-59 199.9 0.0 6.2e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ81123.1 - 1.4e-28 99.9 0.0 1.9e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ81123.1 - 1.7e-07 30.8 0.0 2.7e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDJ81123.1 - 5.9e-05 22.5 0.0 0.00057 19.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like COesterase PF00135.28 CDJ81124.1 - 2e-70 238.2 0.0 2.3e-70 237.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDJ81124.1 - 0.00083 19.3 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Transposase_1 PF01359.18 CDJ81125.1 - 1.1e-27 95.7 0.9 1.9e-27 94.9 0.9 1.4 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_48 PF17906.1 CDJ81125.1 - 4.2e-13 49.2 0.4 9e-13 48.1 0.4 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase DDE_3 PF13358.6 CDJ81125.1 - 6.1e-09 35.8 0.3 8.6e-09 35.3 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 CDJ81125.1 - 0.048 14.3 0.3 0.98 10.1 0.1 3.3 2 1 1 3 3 3 0 Homeodomain-like domain HTH_24 PF13412.6 CDJ81125.1 - 0.18 11.4 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Rer1 PF03248.13 CDJ81126.1 - 8.8e-63 211.1 8.9 9.7e-63 211.0 8.9 1.0 1 0 0 1 1 1 1 Rer1 family Bestrophin PF01062.21 CDJ81126.1 - 0.015 14.7 2.0 0.025 14.0 2.0 1.3 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel WD40 PF00400.32 CDJ81127.1 - 1.4e-17 63.7 9.0 4.1e-06 27.4 0.6 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ81127.1 - 1e-05 25.7 0.0 1 9.7 0.0 4.4 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ81127.1 - 0.047 12.6 0.5 4.9 6.0 0.1 3.2 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CDJ81127.1 - 0.047 13.6 0.0 2.9 7.7 0.0 3.2 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.9 CDJ81127.1 - 0.071 12.8 0.2 0.63 9.7 0.0 2.1 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain HetR_C PF18460.1 CDJ81127.1 - 0.17 11.8 2.3 1.3 9.0 0.0 2.9 3 0 0 3 3 3 0 Heterocyst differentiation regulator C-terminal Hood domain Topoisom_I PF01028.20 CDJ81131.1 - 0.054 12.7 0.2 0.075 12.3 0.2 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, catalytic core PA28_alpha PF02251.18 CDJ81131.1 - 0.2 11.8 2.8 2.4 8.3 0.9 2.7 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit Copine PF07002.16 CDJ81132.1 - 2.7e-43 147.9 0.1 3.8e-43 147.5 0.1 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 CDJ81132.1 - 1.1e-29 102.8 0.0 8.9e-14 51.6 0.0 2.3 2 0 0 2 2 2 2 C2 domain Metallophos PF00149.28 CDJ81133.1 - 1.8e-09 38.4 0.0 3.9e-09 37.3 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDJ81133.1 - 0.002 18.3 0.0 0.0033 17.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ras PF00071.22 CDJ81134.1 - 3.1e-56 189.4 0.0 3.7e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ81134.1 - 5.6e-23 81.4 0.0 8.9e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ81134.1 - 7.1e-09 35.3 0.0 9.7e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDJ81134.1 - 2.5e-07 30.4 0.3 2.5e-06 27.2 0.3 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDJ81134.1 - 3e-06 27.2 0.0 0.1 12.5 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CDJ81134.1 - 3.6e-05 23.8 0.0 5.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 CDJ81134.1 - 0.019 14.7 0.0 0.046 13.5 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.6 CDJ81134.1 - 0.028 14.7 0.0 0.64 10.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 CDJ81134.1 - 0.034 13.7 0.1 0.16 11.5 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.18 CDJ81134.1 - 0.045 13.0 0.0 0.095 12.0 0.0 1.5 1 1 0 1 1 1 0 Septin AAA_25 PF13481.6 CDJ81134.1 - 0.083 12.5 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain PUF PF00806.19 CDJ81135.1 - 3.4e-07 29.6 0.1 0.016 14.9 0.0 4.8 5 0 0 5 5 5 2 Pumilio-family RNA binding repeat Ank_2 PF12796.7 CDJ81136.1 - 5.6e-43 145.4 0.5 1.9e-12 47.6 0.1 4.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ81136.1 - 9e-36 121.8 1.7 4.2e-09 36.8 0.0 6.2 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ81136.1 - 2.3e-31 104.3 0.7 0.021 15.3 0.0 8.4 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 CDJ81136.1 - 5.7e-27 93.4 4.8 8.2e-05 22.8 0.2 8.0 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 CDJ81136.1 - 1.3e-20 72.9 10.8 0.029 14.8 0.2 8.5 7 1 1 8 8 8 6 Ankyrin repeat 7tm_1 PF00001.21 CDJ81137.1 - 7.4e-22 77.9 17.0 9.9e-22 77.5 17.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDJ81137.1 - 7.3e-21 74.8 16.4 4e-19 69.1 16.4 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 CDJ81137.1 - 3.8e-09 36.5 17.0 6.4e-09 35.8 16.6 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 CDJ81137.1 - 1.4e-07 31.2 16.5 2.1e-07 30.6 16.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx WBP-1 PF11669.8 CDJ81137.1 - 0.0047 17.5 1.2 0.084 13.5 0.7 2.6 2 0 0 2 2 2 1 WW domain-binding protein 1 DUF373 PF04123.13 CDJ81137.1 - 0.096 12.1 2.6 0.19 11.1 2.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Pmp3 PF01679.17 CDJ81138.1 - 2.8e-15 56.2 10.9 2.8e-15 56.2 10.9 1.5 2 0 0 2 2 2 1 Proteolipid membrane potential modulator PAN_1 PF00024.26 CDJ81139.1 - 7.9e-18 64.2 15.3 1.3e-06 28.3 1.7 3.5 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.6 CDJ81139.1 - 0.0061 16.4 2.3 0.0061 16.4 2.3 2.7 3 0 0 3 3 3 2 PAN domain TGF_beta PF00019.20 CDJ81141.1 - 4.6e-15 56.5 0.2 9.4e-15 55.5 0.2 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain WD40 PF00400.32 CDJ81143.1 - 1.4e-40 136.5 16.7 5.2e-07 30.3 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ81143.1 - 7.8e-14 51.8 0.0 0.0037 17.5 0.1 5.3 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CDJ81143.1 - 0.0053 16.1 0.0 0.19 11.0 0.0 2.6 1 1 1 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 CDJ81143.1 - 0.0091 15.0 0.2 10 5.0 0.0 3.7 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 CDJ81143.1 - 0.094 11.2 0.0 0.46 8.9 0.0 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain Otopetrin PF03189.13 CDJ81144.1 - 5.6e-69 233.1 30.9 2.2e-46 158.6 23.1 3.2 1 1 1 2 2 2 2 Otopetrin Otopetrin PF03189.13 CDJ81145.1 - 5.8e-84 282.5 22.6 1.6e-82 277.7 18.8 3.1 2 1 0 2 2 2 1 Otopetrin Gemini_mov PF01708.16 CDJ81145.1 - 0.07 12.9 1.7 4.8 7.0 0.0 3.4 3 0 0 3 3 3 0 Geminivirus putative movement protein Retrotrans_gag PF03732.17 CDJ81146.1 - 0.011 16.0 0.1 0.054 13.8 0.1 2.1 1 1 0 1 1 1 0 Retrotransposon gag protein Utp8 PF10395.9 CDJ81146.1 - 0.1 11.1 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Utp8 family Pkinase PF00069.25 CDJ81147.1 - 2.9e-45 154.7 0.0 5.1e-45 153.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ81147.1 - 1e-27 97.1 0.1 1.4e-27 96.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ81147.1 - 0.00024 20.5 0.1 0.00037 19.9 0.1 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDJ81147.1 - 0.00066 19.1 0.0 0.0013 18.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CDJ81151.1 - 6.6e-47 160.1 0.0 8.2e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ81151.1 - 1e-34 120.0 0.0 1.2e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ81151.1 - 1.2e-05 24.8 0.0 2.8e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CDJ81151.1 - 0.0023 16.9 0.0 0.0045 16.0 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CDJ81151.1 - 0.0044 15.9 0.0 0.0078 15.0 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Seadorna_VP7 PF07387.11 CDJ81151.1 - 0.016 14.3 0.1 0.03 13.4 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 CDJ81151.1 - 0.042 13.8 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDJ81151.1 - 0.066 12.8 0.1 0.2 11.2 0.1 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase TPR_12 PF13424.6 CDJ81152.1 - 3.8e-13 49.5 0.3 1.2e-06 28.7 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ81152.1 - 3.1e-05 23.7 0.0 5.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ81152.1 - 0.00024 20.8 0.2 0.00049 19.8 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat NuiA PF07924.11 CDJ81152.1 - 0.007 16.8 0.1 0.1 13.0 0.0 2.1 2 0 0 2 2 2 1 Nuclease A inhibitor-like protein TPR_8 PF13181.6 CDJ81152.1 - 0.0091 16.1 0.1 0.024 14.8 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ81152.1 - 0.0091 16.0 0.1 0.019 15.1 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat BRCT PF00533.26 CDJ81152.1 - 0.1 13.0 0.2 1.2 9.6 0.0 2.4 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Complex1_LYR_2 PF13233.6 CDJ81152.1 - 0.14 12.9 0.0 0.37 11.6 0.0 1.6 1 1 0 1 1 1 0 Complex1_LYR-like TPR_7 PF13176.6 CDJ81152.1 - 0.15 12.1 0.0 0.43 10.7 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Mito_fiss_reg PF05308.11 CDJ81153.1 - 6.1 6.8 6.3 11 6.0 6.3 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator HMMR_N PF15905.5 CDJ81154.1 - 0.0024 17.4 39.2 0.0024 17.4 39.2 8.3 3 1 5 8 8 8 3 Hyaluronan mediated motility receptor N-terminal HIP1_clath_bdg PF16515.5 CDJ81154.1 - 0.0095 16.5 12.6 0.0095 16.5 12.6 13.8 5 2 4 13 13 13 4 Clathrin-binding domain of Huntingtin-interacting protein 1 EGL-1 PF11430.8 CDJ81154.1 - 0.92 9.4 5.8 16 5.5 0.1 3.3 3 0 0 3 3 3 0 Programmed cell death activator EGL-1 Actin PF00022.19 CDJ81155.1 - 9.7e-128 426.2 0.0 1.6e-66 224.6 0.0 2.0 1 1 1 2 2 2 2 Actin RhoGEF PF00621.20 CDJ81156.1 - 2e-13 51.0 0.0 2.5e-13 50.6 0.0 1.0 1 0 0 1 1 1 1 RhoGEF domain Kelch_1 PF01344.25 CDJ81157.1 - 8.8e-56 185.3 9.7 3.6e-15 55.3 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CDJ81157.1 - 2.7e-34 116.3 2.7 1.4e-09 37.9 0.0 6.3 1 1 5 6 6 6 6 Kelch motif Kelch_3 PF13415.6 CDJ81157.1 - 2.1e-26 91.6 6.0 4.5e-11 42.7 0.1 6.0 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 CDJ81157.1 - 2.7e-24 84.2 7.1 8.1e-06 25.6 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 CDJ81157.1 - 5.2e-22 77.4 3.7 0.00016 21.5 0.1 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 CDJ81157.1 - 9.2e-21 73.6 2.5 0.0039 17.2 0.0 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain BACK PF07707.15 CDJ81157.1 - 2.8e-08 33.8 0.0 6.7e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Glyoxal_oxid_N PF07250.11 CDJ81157.1 - 0.0012 18.1 0.4 7.3 5.7 0.0 3.7 1 1 1 3 3 3 2 Glyoxal oxidase N-terminus HTH_26 PF13443.6 CDJ81158.1 - 0.0044 17.4 0.0 0.0083 16.5 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 CDJ81158.1 - 0.042 13.4 0.0 0.32 10.6 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF3602 PF12223.8 CDJ81158.1 - 0.049 14.2 0.6 0.094 13.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) E3_UFM1_ligase PF09743.9 CDJ81158.1 - 0.063 12.9 0.1 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 E3 UFM1-protein ligase 1 HTH_Tnp_ISL3 PF13542.6 CDJ81158.1 - 0.098 12.1 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_32 PF13565.6 CDJ81158.1 - 0.1 13.2 3.1 0.28 11.8 0.2 2.6 3 0 0 3 3 3 0 Homeodomain-like domain HTH_IclR PF09339.10 CDJ81158.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain RVT_1 PF00078.27 CDJ81161.1 - 4.6e-40 137.5 0.0 6.2e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FlbT PF07378.11 CDJ81161.1 - 0.1 12.6 0.0 0.28 11.3 0.0 1.7 2 0 0 2 2 2 0 Flagellar protein FlbT Exo_endo_phos_2 PF14529.6 CDJ81162.1 - 0.0012 18.7 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase SF3a60_bindingd PF12108.8 CDJ81162.1 - 0.1 12.5 1.2 0.21 11.5 0.1 2.0 3 0 0 3 3 3 0 Splicing factor SF3a60 binding domain DUF3995 PF13160.6 CDJ81163.1 - 4 7.8 11.3 1.3 9.4 1.5 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF3995) DUF3278 PF11683.8 CDJ81163.1 - 5.5 7.1 7.3 1.3 9.1 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3278) Lig_chan PF00060.26 CDJ81165.1 - 2.8e-45 153.8 1.6 5e-45 153.0 1.6 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 CDJ81165.1 - 2.8e-40 137.1 0.0 6.2e-40 136.0 0.0 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 CDJ81165.1 - 1.4e-15 57.3 0.0 3.2e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 CDJ81165.1 - 5e-15 55.4 0.0 3.4e-14 52.7 0.0 2.1 2 0 0 2 2 2 1 Receptor family ligand binding region Acyl-CoA_dh_1 PF00441.24 CDJ81166.1 - 1e-36 126.4 0.2 1.5e-36 125.9 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CDJ81166.1 - 3.5e-25 88.9 0.0 6.8e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CDJ81166.1 - 1.4e-22 79.7 0.0 2.7e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CDJ81166.1 - 2.2e-14 53.9 0.3 3.8e-14 53.1 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 CDJ81166.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.6 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Homeodomain PF00046.29 CDJ81167.1 - 6.2e-49 163.7 12.2 3.4e-17 62.0 2.1 3.7 3 0 0 3 3 3 3 Homeodomain zf-C2H2_4 PF13894.6 CDJ81167.1 - 6.2e-18 64.0 56.0 0.26 12.2 0.4 14.3 14 0 0 14 14 14 7 C2H2-type zinc finger zf-C2H2 PF00096.26 CDJ81167.1 - 1.3e-14 53.7 51.4 0.039 14.4 0.1 12.1 12 0 0 12 12 12 7 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CDJ81167.1 - 5e-11 42.6 28.2 0.0043 17.3 0.1 10.2 10 0 0 10 10 10 2 Zinc-finger double-stranded RNA-binding Homeobox_KN PF05920.11 CDJ81167.1 - 2.6e-09 36.9 1.6 0.0016 18.3 0.0 4.7 4 0 0 4 4 4 2 Homeobox KN domain zf-met PF12874.7 CDJ81167.1 - 7.8e-06 26.1 61.7 0.014 15.7 0.1 12.1 14 0 0 14 14 14 4 Zinc-finger of C2H2 type zf-Di19 PF05605.12 CDJ81167.1 - 0.00081 19.6 4.9 0.00081 19.6 4.9 7.8 9 0 0 9 9 9 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 CDJ81167.1 - 0.00093 19.5 63.4 1.4 9.3 0.2 12.8 6 2 6 12 12 12 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 CDJ81167.1 - 0.19 11.7 62.7 0.11 12.5 0.2 10.1 13 0 0 13 13 13 0 C2H2-type zinc finger Peptidase_C1 PF00112.23 CDJ81168.1 - 5.2e-73 245.7 3.5 6.9e-73 245.3 3.5 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CDJ81168.1 - 1.4e-09 38.3 2.1 4.9e-09 36.5 2.2 1.9 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CDJ81168.1 - 5e-07 28.8 2.4 0.00023 20.1 0.1 3.2 2 1 0 3 3 3 2 Peptidase C1-like family GT87 PF09594.10 CDJ81170.1 - 0.0044 16.8 0.2 0.0044 16.8 0.2 1.4 2 0 0 2 2 2 1 Glycosyltransferase family 87 HEAT_2 PF13646.6 CDJ81171.1 - 0.0011 19.4 4.6 3 8.3 0.2 5.6 5 1 0 5 5 5 2 HEAT repeats MOR2-PAG1_C PF14225.6 CDJ81171.1 - 0.0059 16.5 6.1 1.4 8.8 0.0 4.5 4 0 0 4 4 4 2 Cell morphogenesis C-terminal YqfQ PF14181.6 CDJ81171.1 - 0.079 13.2 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 YqfQ-like protein DUF4497 PF14924.6 CDJ81172.1 - 0.027 14.9 0.1 0.045 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4497) Astacin PF01400.24 CDJ81173.1 - 3.9e-38 131.0 0.0 6.2e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 CDJ81173.1 - 0.0027 17.4 0.0 0.0053 16.4 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CDJ81173.1 - 0.0029 17.4 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 CDJ81173.1 - 0.016 14.2 0.1 0.024 13.6 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.6 CDJ81173.1 - 0.029 14.9 1.7 0.047 14.2 0.6 2.1 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CDJ81173.1 - 0.06 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Flu_NS2 PF00601.19 CDJ81173.1 - 0.066 13.5 0.4 0.14 12.5 0.4 1.5 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) DUF4953 PF16313.5 CDJ81173.1 - 0.19 10.9 0.6 0.54 9.4 0.0 1.8 2 0 0 2 2 2 0 Met-zincin Astacin PF01400.24 CDJ81174.1 - 1.1e-36 126.2 0.2 1.8e-36 125.6 0.2 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 CDJ81174.1 - 0.0021 18.6 0.1 0.0048 17.4 0.0 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CDJ81174.1 - 0.0066 16.1 0.1 0.013 15.1 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CDJ81174.1 - 0.0078 16.1 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Matrixin Reprolysin_5 PF13688.6 CDJ81174.1 - 0.036 14.2 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 CDJ81174.1 - 0.075 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Flu_NS2 PF00601.19 CDJ81174.1 - 0.093 13.0 0.4 0.17 12.2 0.4 1.4 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) Glyco_hydro_31 PF01055.26 CDJ81175.1 - 4.1e-137 458.0 3.3 5.4e-137 457.6 3.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 CDJ81175.1 - 1.1e-17 64.2 0.0 2.7e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 CDJ81175.1 - 2.5e-07 30.4 2.5 6.2e-07 29.2 2.5 1.6 1 0 0 1 1 1 1 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.6 CDJ81175.1 - 3.4e-07 30.5 0.1 1.1e-06 28.8 0.1 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 CDJ81175.1 - 0.086 13.1 0.1 0.27 11.5 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) Cadherin_C PF01049.17 CDJ81175.1 - 0.12 12.7 0.1 0.39 11.0 0.0 1.8 2 0 0 2 2 2 0 Cadherin cytoplasmic region 2-ph_phosp PF04029.14 CDJ81176.1 - 0.0019 17.4 0.0 0.0024 17.1 0.0 1.2 1 0 0 1 1 1 1 2-phosphosulpholactate phosphatase UVR PF02151.19 CDJ81176.1 - 0.088 12.6 0.8 0.088 12.6 0.8 2.7 3 0 0 3 3 3 0 UvrB/uvrC motif DUF4035 PF13227.6 CDJ81176.1 - 0.15 11.8 0.0 24 4.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4035) TTR-52 PF01060.23 CDJ81177.1 - 5.9e-26 91.0 0.2 8e-26 90.6 0.2 1.2 1 0 0 1 1 1 1 Transthyretin-like family Transthyretin PF00576.21 CDJ81177.1 - 0.087 13.5 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 HIUase/Transthyretin family bMG3 PF11974.8 CDJ81177.1 - 0.088 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain adh_short PF00106.25 CDJ81178.1 - 1.4e-36 125.8 0.3 7.5e-36 123.4 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ81178.1 - 4.5e-30 104.9 0.6 1.8e-29 103.0 0.6 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ81178.1 - 1.8e-07 31.2 0.3 7.1e-07 29.3 0.1 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 CDJ81178.1 - 0.0037 16.8 0.0 0.025 14.1 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 CDJ81178.1 - 0.051 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ABC_tran PF00005.27 CDJ81179.1 - 1.8e-54 184.0 0.0 2.1e-28 99.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CDJ81179.1 - 3.1e-38 131.8 56.4 1.3e-28 100.1 18.2 3.1 3 0 0 3 3 3 3 ABC-2 family transporter protein AAA_21 PF13304.6 CDJ81179.1 - 6.4e-27 95.1 0.0 6.4e-09 36.1 0.0 4.4 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 CDJ81179.1 - 3.8e-05 23.1 0.2 0.23 10.7 0.0 3.3 3 0 0 3 3 3 2 Zeta toxin AAA_23 PF13476.6 CDJ81179.1 - 5.4e-05 23.8 0.2 0.0024 18.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ81179.1 - 6.1e-05 23.5 0.1 0.29 11.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 CDJ81179.1 - 8.7e-05 22.0 0.0 0.016 14.7 0.1 3.3 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CDJ81179.1 - 0.00025 20.7 0.2 0.0088 15.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CDJ81179.1 - 0.0005 20.0 0.2 0.028 14.3 0.1 2.8 3 0 0 3 3 3 1 RsgA GTPase AAA_15 PF13175.6 CDJ81179.1 - 0.0012 18.6 0.0 0.0054 16.5 0.0 2.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 CDJ81179.1 - 0.024 14.4 1.4 1.1 9.0 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 CDJ81179.1 - 0.047 13.3 0.3 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CDJ81179.1 - 0.16 12.2 0.2 3.7 7.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CDJ81179.1 - 0.38 10.9 1.7 18 5.5 0.2 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase ANF_receptor PF01094.28 CDJ81180.1 - 2.4e-63 214.4 0.0 3.1e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 CDJ81180.1 - 2.3e-55 187.9 24.3 3.9e-55 187.2 24.3 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 CDJ81180.1 - 0.00069 19.4 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein NCD3G PF07562.14 CDJ81180.1 - 0.11 12.5 0.7 0.27 11.2 0.7 1.6 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR DUF5438 PF17506.2 CDJ81180.1 - 0.14 12.5 0.2 0.43 10.9 0.2 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5438) PAE PF03283.13 CDJ81180.1 - 0.16 11.1 0.1 0.24 10.5 0.1 1.2 1 0 0 1 1 1 0 Pectinacetylesterase ECM1 PF05782.11 CDJ81181.1 - 0.17 10.8 0.3 0.2 10.6 0.3 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) SSP160 PF06933.11 CDJ81182.1 - 8.8 4.4 6.8 13 3.8 6.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TerB PF05099.13 CDJ81184.1 - 0.029 14.4 0.0 0.11 12.4 0.0 1.9 1 1 1 2 2 2 0 Tellurite resistance protein TerB DUF5497 PF17601.2 CDJ81184.1 - 0.12 12.8 0.4 0.58 10.5 0.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5497) PALP PF00291.25 CDJ81185.1 - 2e-31 109.5 1.0 2.4e-31 109.2 1.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_C1_2 PF03051.15 CDJ81185.1 - 0.1 11.4 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Peptidase C1-like family G-patch PF01585.23 CDJ81186.1 - 2.9e-12 46.3 0.9 7.9e-12 44.9 0.9 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CDJ81186.1 - 0.0013 18.8 0.6 0.0013 18.8 0.6 4.8 7 1 0 7 7 7 1 G-patch domain Metallophos PF00149.28 CDJ81187.1 - 4.9e-11 43.5 0.9 1.2e-10 42.2 0.9 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDJ81187.1 - 8.9e-09 35.8 0.0 2.1e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Cation_ATPase_C PF00689.21 CDJ81187.1 - 0.23 11.2 5.4 0.57 9.9 5.4 1.7 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF2100 PF09873.9 CDJ81189.1 - 0.057 13.3 0.0 0.069 13.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2100) RVT_1 PF00078.27 CDJ81190.1 - 4.7e-10 39.4 0.1 2.4e-09 37.1 0.1 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GIY-YIG PF01541.24 CDJ81190.1 - 0.0078 16.5 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain DUF812 PF05667.11 CDJ81191.1 - 0.007 15.3 19.9 0.012 14.5 19.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) BAG6 PF12057.8 CDJ81191.1 - 0.028 14.1 0.8 0.11 12.2 0.2 2.2 1 1 1 2 2 2 0 BCL2-associated athanogene 6 Atg14 PF10186.9 CDJ81191.1 - 0.072 12.2 18.5 0.18 10.8 18.5 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_13 PF13166.6 CDJ81191.1 - 0.082 11.5 18.0 0.13 10.9 18.0 1.2 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.10 CDJ81191.1 - 0.33 11.1 14.6 0.15 12.3 7.7 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Prominin PF05478.11 CDJ81191.1 - 0.36 8.7 5.2 0.52 8.2 5.2 1.2 1 0 0 1 1 1 0 Prominin Laminin_II PF06009.12 CDJ81191.1 - 0.37 10.8 13.6 0.092 12.8 9.3 2.0 1 1 1 2 2 2 0 Laminin Domain II Phage_GP20 PF06810.11 CDJ81191.1 - 0.46 10.3 18.0 0.013 15.3 9.5 2.3 1 1 0 2 2 2 0 Phage minor structural protein GP20 DUF3584 PF12128.8 CDJ81191.1 - 0.83 7.1 27.7 1.3 6.4 27.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ADIP PF11559.8 CDJ81191.1 - 2.4 8.3 33.5 0.18 11.8 17.5 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding EzrA PF06160.12 CDJ81191.1 - 3.3 5.8 21.3 11 4.0 19.7 1.9 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA MscS_porin PF12795.7 CDJ81191.1 - 3.4 7.1 31.4 4.1 6.9 4.5 2.5 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain FAM76 PF16046.5 CDJ81191.1 - 4.1 6.7 21.1 28 3.9 20.6 2.3 1 1 0 1 1 1 0 FAM76 protein Lectin_N PF03954.14 CDJ81191.1 - 5.4 6.8 8.3 0.48 10.2 0.3 2.8 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain HemX PF04375.14 CDJ81191.1 - 7.7 5.7 22.7 0.9 8.8 11.9 2.3 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Cep57_MT_bd PF06657.13 CDJ81191.1 - 7.7 7.0 17.9 18 5.9 10.2 3.4 2 1 1 3 3 2 0 Centrosome microtubule-binding domain of Cep57 DASH_Spc34 PF08657.10 CDJ81191.1 - 8.1 6.2 18.1 2.1 8.1 9.9 2.4 1 1 1 2 2 2 0 DASH complex subunit Spc34 rRNA_processing PF08524.11 CDJ81192.1 - 4e-11 43.1 18.4 4.4e-11 43.0 18.4 1.0 1 0 0 1 1 1 1 rRNA processing HXXSHH PF07586.11 CDJ81192.1 - 0.038 13.6 1.5 0.046 13.3 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) NAD_binding_4 PF07993.12 CDJ81192.1 - 0.067 12.3 1.6 0.096 11.8 1.6 1.3 1 0 0 1 1 1 0 Male sterility protein Spo0A_C PF08769.11 CDJ81192.1 - 0.076 13.1 2.4 0.098 12.8 0.9 1.8 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal CDC37_N PF03234.14 CDJ81192.1 - 0.42 11.5 7.9 0.46 11.4 7.9 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Alb1 PF09135.11 CDJ81192.1 - 0.59 11.0 15.5 0.4 11.6 14.0 1.5 1 1 0 1 1 1 0 Alb1 Rotamase PF00639.21 CDJ81192.1 - 2.4 9.2 6.6 4.2 8.4 6.0 1.9 1 1 0 1 1 1 0 PPIC-type PPIASE domain B277 PF17623.2 CDJ81192.1 - 4.3 6.3 9.8 5.2 6.1 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function UQ_con PF00179.26 CDJ81193.1 - 2.6e-23 82.2 0.1 5.1e-23 81.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CDJ81193.1 - 0.073 13.4 0.0 0.28 11.5 0.0 2.0 1 0 0 1 1 1 0 RWD domain UFC1 PF08694.11 CDJ81193.1 - 0.16 11.6 0.0 0.41 10.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Glutaredoxin PF00462.24 CDJ81194.1 - 3.1e-15 56.1 0.0 6.5e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin Selenoprotein_S PF06936.11 CDJ81194.1 - 8.3e-06 25.7 1.2 1.2e-05 25.2 1.2 1.3 1 0 0 1 1 1 1 Selenoprotein S (SelS) Thioredoxin_2 PF13098.6 CDJ81194.1 - 0.00012 22.5 0.2 0.00068 20.1 0.0 2.2 2 2 0 2 2 2 1 Thioredoxin-like domain GST_N_3 PF13417.6 CDJ81194.1 - 0.0025 18.2 0.0 0.016 15.6 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 CDJ81194.1 - 0.0033 17.8 0.0 0.0076 16.6 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 CDJ81194.1 - 0.0035 17.3 0.0 0.011 15.8 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin domain Thioredoxin_4 PF13462.6 CDJ81194.1 - 0.064 13.4 2.9 14 5.8 0.0 3.0 1 1 2 3 3 3 0 Thioredoxin Thioredoxin_7 PF13899.6 CDJ81194.1 - 0.12 12.5 0.9 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like tRNA-synt_His PF13393.6 CDJ81195.1 - 0.11 11.8 0.9 0.3 10.3 0.1 1.9 2 0 0 2 2 2 0 Histidyl-tRNA synthetase HD_2 PF12917.7 CDJ81195.1 - 2 8.2 6.7 4.4 7.0 0.9 2.8 3 1 1 4 4 4 0 HD containing hydrolase-like enzyme DUF5356 PF17309.2 CDJ81196.1 - 4.1e-17 62.4 1.9 5.2e-17 62.1 1.9 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5356) RVT_1 PF00078.27 CDJ81197.1 - 2.4e-14 53.4 0.0 3.9e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Gal-bind_lectin PF00337.22 CDJ81198.1 - 6e-22 77.6 0.4 7.6e-22 77.3 0.4 1.1 1 0 0 1 1 1 1 Galactoside-binding lectin FAD_binding_3 PF01494.19 CDJ81198.1 - 0.23 10.7 0.0 0.26 10.5 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain Gal-bind_lectin PF00337.22 CDJ81199.1 - 7.7e-13 48.1 0.1 8.7e-13 48.0 0.1 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin Big_3_4 PF13754.6 CDJ81199.1 - 0.13 12.1 0.0 0.18 11.5 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function Gal-bind_lectin PF00337.22 CDJ81200.1 - 1.2e-22 79.9 0.4 1.4e-22 79.6 0.4 1.1 1 0 0 1 1 1 1 Galactoside-binding lectin DpaA_N PF16924.5 CDJ81200.1 - 0.13 12.4 0.0 0.41 10.7 0.0 1.7 1 1 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain Str_synth PF03088.16 CDJ81201.1 - 5.4e-15 55.3 0.0 1.4e-14 54.0 0.0 1.7 2 0 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 CDJ81201.1 - 7.9e-05 22.4 0.0 0.00022 20.9 0.0 1.6 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Sugar_tr PF00083.24 CDJ81202.1 - 6.5e-17 61.5 25.2 1.4e-16 60.5 25.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ81202.1 - 9.1e-16 57.7 37.9 3.2e-08 32.9 27.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1279 PF06916.13 CDJ81202.1 - 8 7.1 6.4 0.55 10.8 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) TIL PF01826.17 CDJ81203.1 - 4.4e-05 23.7 19.3 4.4e-05 23.7 19.3 1.4 2 0 0 2 2 2 1 Trypsin Inhibitor like cysteine rich domain DUF1308 PF07000.11 CDJ81204.1 - 1.2e-55 187.9 0.1 2e-55 187.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) WD40 PF00400.32 CDJ81205.1 - 2.4e-25 88.3 7.8 0.0018 19.0 0.1 6.7 6 1 1 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ81205.1 - 5.6e-11 42.6 0.5 0.0075 16.6 0.1 4.5 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CDJ81205.1 - 1.4e-06 27.8 2.6 0.0018 17.7 0.8 3.0 2 1 1 3 3 3 3 WD40-like domain eIF2A PF08662.11 CDJ81205.1 - 8.2e-05 22.6 0.3 0.38 10.6 0.0 3.7 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 CDJ81205.1 - 0.0021 17.7 0.2 0.12 12.0 0.0 2.2 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.21 CDJ81205.1 - 0.006 16.5 0.1 2.6 8.1 0.0 3.5 3 0 0 3 3 3 1 PQQ enzyme repeat Sporozoite_P67 PF05642.11 CDJ81206.1 - 1.3 7.0 3.0 1.5 6.8 3.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Hydrolase PF00702.26 CDJ81207.1 - 2.3e-07 31.3 0.0 3.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDJ81207.1 - 0.012 15.3 0.1 0.015 15.0 0.1 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF5356 PF17309.2 CDJ81207.1 - 0.19 11.7 0.3 0.44 10.5 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5356) Pkinase PF00069.25 CDJ81208.1 - 4.6e-61 206.5 0.0 5.3e-61 206.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ81208.1 - 5.1e-43 147.2 0.0 6.3e-43 146.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ81208.1 - 2.9e-07 30.1 0.0 2.8e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.11 CDJ81208.1 - 0.0068 15.5 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 CDJ81208.1 - 0.069 12.5 0.1 0.099 12.0 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDJ81208.1 - 0.17 10.6 0.1 0.24 10.1 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase PB1 PF00564.24 CDJ81209.1 - 9.7e-06 25.4 0.0 0.00012 21.9 0.0 2.0 2 0 0 2 2 2 1 PB1 domain zf_C2H2_13 PF18508.1 CDJ81209.1 - 0.078 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Zinc finger domain CHGN PF05679.16 CDJ81210.1 - 5.5e-148 494.0 0.0 1.1e-147 493.0 0.0 1.5 1 1 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 CDJ81210.1 - 7.2e-14 51.8 0.0 1.1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Fringe-like Glyco_transf_7C PF02709.14 CDJ81210.1 - 2e-09 37.0 0.0 5.4e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CDJ81210.1 - 1.2e-07 31.5 0.1 6.5e-07 29.1 0.1 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CDJ81210.1 - 0.0036 17.1 0.1 1.1 9.1 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Galactosyl_T PF01762.21 CDJ81210.1 - 0.03 14.2 0.0 0.3 10.9 0.0 2.5 3 0 0 3 3 3 0 Galactosyltransferase DIE2_ALG10 PF04922.12 CDJ81211.1 - 2.3e-26 93.0 4.7 9e-26 91.1 4.7 1.7 1 1 0 1 1 1 1 DIE2/ALG10 family Frizzled PF01534.17 CDJ81212.1 - 8.3e-95 317.5 17.4 8.3e-95 317.5 17.4 1.5 2 0 0 2 2 2 1 Frizzled/Smoothened family membrane region Fz PF01392.22 CDJ81212.1 - 4.6e-31 107.7 3.8 1.3e-30 106.2 3.8 1.8 1 0 0 1 1 1 1 Fz domain Tetraspanin PF00335.20 CDJ81213.1 - 2e-42 145.4 14.5 2.3e-42 145.3 14.5 1.0 1 0 0 1 1 1 1 Tetraspanin family His_Phos_2 PF00328.22 CDJ81214.1 - 5.3e-115 384.8 1.0 7.1e-115 384.4 1.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 CDJ81214.1 - 2.5e-38 130.1 0.4 7.7e-38 128.5 0.2 2.0 2 0 0 2 2 2 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 CDJ81214.1 - 0.0015 18.2 0.0 0.0051 16.4 0.0 1.8 2 0 0 2 2 2 1 RimK-like ATP-grasp domain DUF848 PF05852.11 CDJ81214.1 - 0.18 11.9 0.5 0.49 10.5 0.5 1.7 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF2650 PF10853.8 CDJ81217.1 - 1.5e-21 75.8 5.5 2.5e-21 75.1 5.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2650) Synaptobrevin PF00957.21 CDJ81217.1 - 0.97 9.3 3.6 0.33 10.8 0.4 1.8 2 0 0 2 2 2 0 Synaptobrevin TMPIT PF07851.13 CDJ81218.1 - 9.6e-120 399.7 17.3 1.1e-119 399.5 17.3 1.0 1 0 0 1 1 1 1 TMPIT-like protein DUF1722 PF08349.11 CDJ81218.1 - 0.0059 16.9 1.0 0.013 15.7 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1722) Snapin_Pallidin PF14712.6 CDJ81218.1 - 0.032 14.7 2.9 0.08 13.4 3.0 1.6 1 1 0 1 1 1 0 Snapin/Pallidin Rho_Binding PF08912.11 CDJ81218.1 - 0.033 15.0 1.7 9.4 7.1 0.8 2.3 2 0 0 2 2 2 0 Rho Binding FliJ PF02050.16 CDJ81218.1 - 0.048 13.9 1.0 0.079 13.2 1.0 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4393 PF14337.6 CDJ81218.1 - 0.076 12.8 0.4 0.12 12.2 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) End3 PF12761.7 CDJ81218.1 - 0.15 12.2 1.5 0.21 11.8 1.5 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF922 PF06037.11 CDJ81218.1 - 0.22 11.3 1.0 0.31 10.8 0.2 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF922) SNF PF00209.18 CDJ81219.1 - 4e-141 471.3 49.0 4.9e-141 471.0 49.0 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Caveolin PF01146.17 CDJ81219.1 - 0.0051 16.8 3.9 0.0051 16.8 3.9 3.7 4 0 0 4 4 4 1 Caveolin SPATA25 PF15218.6 CDJ81219.1 - 0.053 13.3 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 25 Hira PF07569.11 CDJ81220.1 - 5.9e-22 78.5 1.9 1.2e-20 74.3 0.0 3.1 3 1 0 3 3 3 1 TUP1-like enhancer of split WD40 PF00400.32 CDJ81220.1 - 6.2e-22 77.5 27.3 1.6e-06 28.7 0.2 8.8 8 1 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ81220.1 - 4.7e-15 55.7 1.6 0.095 13.0 0.1 6.2 3 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 CDJ81220.1 - 5.1e-06 26.2 0.1 1.2e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 HIRA B motif Ge1_WD40 PF16529.5 CDJ81220.1 - 7.8e-06 25.1 1.0 3.1 6.6 0.0 4.9 4 1 1 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 CDJ81220.1 - 0.0024 17.0 0.8 0.045 12.8 0.0 2.5 2 1 1 3 3 3 1 Coatomer WD associated region IKI3 PF04762.12 CDJ81220.1 - 0.016 13.2 0.9 1.6 6.6 0.5 2.7 2 1 0 2 2 2 0 IKI3 family TFIIIC_delta PF12657.7 CDJ81220.1 - 0.38 10.7 3.3 0.31 11.0 0.2 2.5 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term PD40 PF07676.12 CDJ81220.1 - 0.39 10.7 2.3 1.1e+02 2.9 0.2 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Globin PF00042.22 CDJ81222.1 - 4.5e-13 49.7 0.1 7.2e-13 49.1 0.1 1.3 1 0 0 1 1 1 1 Globin DUF1758 PF05585.12 CDJ81223.1 - 6.5e-07 29.3 0.0 1.2e-06 28.3 0.0 1.4 1 1 0 1 1 1 1 Putative peptidase (DUF1758) CPSF_A PF03178.15 CDJ81224.1 - 2e-70 237.7 0.0 8.9e-70 235.5 0.0 2.1 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.9 CDJ81224.1 - 1.5e-41 142.6 0.0 2.7e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF775 PF05603.12 CDJ81225.1 - 1.2e-41 142.4 0.0 1.8e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF775) RRM_1 PF00076.22 CDJ81226.1 - 5.4e-31 106.2 0.2 6.5e-16 57.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ81226.1 - 3.8e-05 23.7 0.2 0.067 13.3 0.0 2.7 2 2 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CDJ81226.1 - 6.9e-05 22.8 0.3 0.098 12.7 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 CDJ81226.1 - 0.091 12.5 0.7 2.4 7.9 0.0 2.7 3 0 0 3 3 3 0 Ribonuclease B OB domain Collagen PF01391.18 CDJ81227.1 - 4.3e-26 90.4 109.6 4.6e-10 39.1 33.8 4.0 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ81227.1 - 1.2e-21 76.5 0.3 1.5e-21 76.1 0.3 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain COX14 PF14880.6 CDJ81227.1 - 0.29 11.0 5.2 0.45 10.4 5.2 1.1 1 0 0 1 1 1 0 Cytochrome oxidase c assembly RRM_1 PF00076.22 CDJ81228.1 - 1.1e-06 28.3 0.0 0.0048 16.7 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Apt1 PF10351.9 CDJ81228.1 - 3.1 6.5 7.7 4.9 5.9 7.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 CDJ81228.1 - 3.7 5.7 10.3 5.7 5.1 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleoporin_FG2 PF15967.5 CDJ81229.1 - 0.0056 15.3 5.8 0.0066 15.0 5.8 1.0 1 0 0 1 1 1 1 Nucleoporin FG repeated region Atrophin-1 PF03154.15 CDJ81229.1 - 0.14 10.4 8.2 0.16 10.2 8.2 1.0 1 0 0 1 1 1 0 Atrophin-1 family Frizzled PF01534.17 CDJ81232.1 - 2.7e-96 322.4 10.2 4e-96 321.9 10.2 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 CDJ81232.1 - 1.4e-25 90.0 2.9 2.8e-25 89.1 2.9 1.5 1 0 0 1 1 1 1 Fz domain GPI2 PF06432.11 CDJ81232.1 - 0.28 10.6 5.4 0.21 11.0 2.7 2.0 1 1 1 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4064 PF13273.6 CDJ81232.1 - 0.42 10.9 4.9 2 8.7 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Peptidase_C2 PF00648.21 CDJ81233.1 - 4.2e-75 252.5 0.0 5.9e-75 252.1 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease zf-RanBP PF00641.18 CDJ81233.1 - 0.012 14.9 20.0 0.031 13.6 6.7 2.6 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DZR PF12773.7 CDJ81233.1 - 0.031 14.3 7.5 0.55 10.3 7.5 2.5 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 CDJ81233.1 - 5.3 7.9 9.1 4.1 8.2 1.1 2.8 2 0 0 2 2 2 0 zinc-ribbon family zf-RING_10 PF16685.5 CDJ81233.1 - 7.1 6.9 7.3 0.8 9.9 0.6 2.6 2 0 0 2 2 2 0 zinc RING finger of MSL2 Ribonuclease_3 PF00636.26 CDJ81234.1 - 5.1e-44 149.2 0.0 1.7e-21 76.8 0.0 3.1 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CDJ81234.1 - 9.7e-41 138.9 0.0 3.8e-20 72.3 0.0 3.4 3 0 0 3 3 3 2 Ribonuclease-III-like dsrm PF00035.26 CDJ81234.1 - 1.8e-09 38.1 0.0 4.2e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif DUF2841 PF11001.8 CDJ81234.1 - 0.0073 16.4 1.9 0.0097 16.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) ALIX_LYPXL_bnd PF13949.6 CDJ81234.1 - 0.8 8.9 9.6 1.6 8.0 0.1 2.7 3 0 0 3 3 3 0 ALIX V-shaped domain binding to HIV UNC45-central PF11701.8 CDJ81235.1 - 1e-23 84.0 0.1 5.9e-22 78.3 0.1 2.9 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central TPR_2 PF07719.17 CDJ81235.1 - 1e-07 31.5 18.1 0.0087 16.1 0.5 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ81235.1 - 0.00017 21.2 8.3 0.035 13.9 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ81235.1 - 0.00032 20.9 2.7 0.00032 20.9 2.7 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ81235.1 - 0.16 12.2 7.4 2.2 8.7 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ81235.1 - 0.25 11.5 5.4 0.32 11.2 1.3 3.3 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ81235.1 - 0.3 11.7 29.6 0.059 14.0 5.8 4.8 3 1 1 4 4 4 0 Tetratricopeptide repeat Methyltransf_31 PF13847.6 CDJ81236.1 - 2.6e-21 76.0 0.0 1.3e-17 64.0 0.0 3.0 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ81236.1 - 1.3e-14 54.6 0.0 1.2e-11 45.1 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ81236.1 - 4.8e-13 49.6 0.0 4.1e-10 40.2 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ81236.1 - 6.7e-12 46.0 0.2 6e-11 43.0 0.2 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ81236.1 - 9.6e-09 34.9 0.1 1.8e-08 34.0 0.1 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 CDJ81236.1 - 2.1e-08 34.2 0.0 3.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CDJ81236.1 - 0.0075 15.7 0.3 0.65 9.4 0.0 2.9 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_32 PF13679.6 CDJ81236.1 - 0.036 14.0 0.0 2.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_8 PF05148.15 CDJ81236.1 - 0.13 12.1 0.0 0.37 10.6 0.0 1.7 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_31 PF13847.6 CDJ81237.1 - 5.2e-54 182.2 0.0 2e-26 92.6 0.0 2.8 3 0 0 3 3 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ81237.1 - 1.5e-41 141.0 0.0 9.2e-20 71.1 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ81237.1 - 3.3e-39 133.5 0.3 1.3e-18 67.5 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ81237.1 - 6.9e-34 116.6 0.1 7.2e-16 58.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ81237.1 - 3.2e-25 88.8 0.0 7.8e-12 45.0 0.0 2.7 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 CDJ81237.1 - 4.2e-22 78.7 0.0 1.4e-10 41.2 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_4 PF02390.17 CDJ81237.1 - 7.1e-18 64.7 0.1 9.9e-08 31.6 0.0 3.1 4 0 0 4 4 4 2 Putative methyltransferase MTS PF05175.14 CDJ81237.1 - 3.6e-13 49.4 0.0 1e-05 25.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_32 PF13679.6 CDJ81237.1 - 2e-11 44.1 0.0 5.9e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain PCMT PF01135.19 CDJ81237.1 - 2.5e-11 43.7 0.0 0.00048 19.9 0.0 3.1 3 0 0 3 3 3 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 CDJ81237.1 - 1.3e-08 34.4 0.1 0.0053 16.1 0.0 2.3 2 0 0 2 2 2 2 O-methyltransferase domain DUF938 PF06080.12 CDJ81237.1 - 8.9e-07 28.9 0.0 0.0038 17.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF938) MetW PF07021.12 CDJ81237.1 - 1.3e-06 28.1 0.0 0.039 13.6 0.0 2.3 2 0 0 2 2 2 2 Methionine biosynthesis protein MetW CMAS PF02353.20 CDJ81237.1 - 3.8e-06 26.4 0.0 0.03 13.6 0.0 2.2 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.6 CDJ81237.1 - 8.7e-06 26.7 0.0 0.056 14.5 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain GidB PF02527.15 CDJ81237.1 - 2.1e-05 23.9 0.0 0.19 11.0 0.0 2.4 2 0 0 2 2 2 2 rRNA small subunit methyltransferase G Methyltransf_5 PF01795.19 CDJ81237.1 - 0.00014 21.4 0.0 0.3 10.6 0.0 2.3 2 0 0 2 2 2 2 MraW methylase family Methyltransf_8 PF05148.15 CDJ81237.1 - 0.00015 21.7 0.0 0.99 9.2 0.0 3.2 4 0 0 4 4 4 2 Hypothetical methyltransferase Methyltransf_9 PF08003.11 CDJ81237.1 - 0.0006 18.8 0.0 0.94 8.3 0.0 3.0 4 0 0 4 4 4 2 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 CDJ81237.1 - 0.00063 19.7 0.0 0.25 11.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CDJ81237.1 - 0.0007 19.1 0.0 0.61 9.4 0.0 2.3 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) Dimerisation PF08100.11 CDJ81237.1 - 0.0015 18.5 0.0 1.9 8.6 0.0 2.6 2 0 0 2 2 2 1 Dimerisation domain TrmB PF01978.19 CDJ81237.1 - 0.0067 16.3 0.0 3.6 7.6 0.0 2.6 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Dimerisation2 PF16864.5 CDJ81237.1 - 0.008 16.1 0.0 3 7.9 0.0 2.8 3 0 0 3 3 2 1 Dimerisation domain Pyridox_ox_2 PF12900.7 CDJ81237.1 - 0.012 15.6 0.1 3.5 7.6 0.0 2.4 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase HTH_23 PF13384.6 CDJ81237.1 - 0.014 15.2 0.0 4.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain CRAL_TRIO_N PF03765.15 CDJ81237.1 - 0.064 13.5 0.3 20 5.5 0.0 2.5 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain HTH_42 PF06224.12 CDJ81237.1 - 0.082 12.4 0.0 3.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain DmsC PF04976.12 CDJ81237.1 - 0.12 11.8 0.2 4.9 6.6 0.1 2.2 2 0 0 2 2 2 0 DMSO reductase anchor subunit (DmsC) Globin PF00042.22 CDJ81238.1 - 0.0014 19.1 0.1 0.0021 18.6 0.1 1.3 1 0 0 1 1 1 1 Globin Kunitz_BPTI PF00014.23 CDJ81239.1 - 3.2e-06 27.3 4.7 5.1e-06 26.6 4.7 1.3 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain SecE PF00584.20 CDJ81240.1 - 6.6e-17 61.2 0.0 7.5e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex CbtB PF09489.10 CDJ81240.1 - 0.16 12.1 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) P-mevalo_kinase PF04275.14 CDJ81241.1 - 2.8e-39 133.6 0.0 4.5e-39 132.9 0.0 1.3 1 0 0 1 1 1 1 Phosphomevalonate kinase AAA_18 PF13238.6 CDJ81241.1 - 0.076 13.6 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF773 PF05600.12 CDJ81243.1 - 2.4e-150 501.7 10.2 2.8e-150 501.4 10.2 1.0 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 Cbl_N PF02262.16 CDJ81243.1 - 0.31 11.1 3.0 0.59 10.1 0.4 2.4 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 RhoGEF67_u2 PF16614.5 CDJ81243.1 - 0.46 10.6 3.0 0.69 10.0 0.1 2.4 2 0 0 2 2 2 0 Unstructured region two on RhoGEF 6 and 7 60KD_IMP PF02096.20 CDJ81243.1 - 4.2 7.2 6.1 18 5.2 1.2 2.6 2 1 0 2 2 2 0 60Kd inner membrane protein DUF2524 PF10732.9 CDJ81243.1 - 8.3 6.8 12.0 19 5.6 1.5 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2524) Ist1 PF03398.14 CDJ81244.1 - 2.5e-59 199.9 0.8 3.2e-59 199.5 0.8 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway UCR_14kD PF02271.16 CDJ81245.1 - 1.5e-25 89.0 0.3 1.8e-25 88.8 0.3 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit CHCH PF06747.13 CDJ81246.1 - 0.012 15.7 3.3 0.05 13.7 0.7 3.1 2 0 0 2 2 2 0 CHCH domain ARL2_Bind_BART PF11527.8 CDJ81246.1 - 0.11 12.7 2.6 0.52 10.4 0.1 2.5 1 1 1 2 2 2 0 The ARF-like 2 binding protein BART Rab3-GTPase_cat PF13890.6 CDJ81247.1 - 5.5e-46 156.2 0.7 2.1e-45 154.3 0.7 2.0 1 1 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit KH_1 PF00013.29 CDJ81248.1 - 3.6e-23 81.2 2.2 4.8e-11 42.3 0.1 2.3 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 CDJ81248.1 - 1.6e-10 40.6 2.2 4.3e-05 23.2 0.2 2.3 1 1 1 2 2 2 2 KH domain KH_4 PF13083.6 CDJ81248.1 - 2.5e-05 24.1 0.3 0.084 12.8 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 CDJ81248.1 - 0.0022 18.0 1.9 0.74 9.9 0.1 2.4 2 0 0 2 2 2 2 NusA-like KH domain KH_1 PF00013.29 CDJ81249.1 - 3.6e-09 36.3 0.0 1.1e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 KH domain Dimerisation PF08100.11 CDJ81249.1 - 0.15 12.1 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain KH_1 PF00013.29 CDJ81250.1 - 9.3e-21 73.4 3.5 2.5e-09 36.8 0.4 2.7 3 0 0 3 3 3 2 KH domain KH_2 PF07650.17 CDJ81250.1 - 2e-09 37.2 2.2 0.00024 20.8 0.3 2.3 1 1 1 2 2 2 2 KH domain KH_4 PF13083.6 CDJ81250.1 - 8.9e-05 22.3 0.7 0.053 13.4 0.1 2.6 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 CDJ81250.1 - 0.0091 16.1 1.0 3.3 7.9 0.1 2.4 2 0 0 2 2 2 2 NusA-like KH domain SNAP PF14938.6 CDJ81251.1 - 2.3e-20 73.2 14.0 8e-20 71.4 13.7 1.8 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 CDJ81251.1 - 9.8e-10 38.6 18.3 6.5e-05 23.1 0.8 3.7 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_MalT PF17874.1 CDJ81251.1 - 3.6e-05 23.3 4.8 5.5e-05 22.7 2.5 1.9 1 1 1 2 2 2 2 MalT-like TPR region TPR_14 PF13428.6 CDJ81251.1 - 0.00095 19.8 18.3 4.2 8.5 0.6 6.4 4 2 3 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ81251.1 - 0.0032 18.0 13.1 0.67 10.7 0.2 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat DUF2989 PF11207.8 CDJ81251.1 - 0.007 16.1 0.8 0.0098 15.7 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2989) TPR_16 PF13432.6 CDJ81251.1 - 0.0096 16.5 16.6 0.89 10.3 1.4 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ81251.1 - 0.035 14.3 9.3 2.9 8.3 0.0 5.4 5 2 1 6 6 6 0 Tetratricopeptide repeat FANCI_S3 PF14677.6 CDJ81251.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 FANCI solenoid 3 TPR_7 PF13176.6 CDJ81251.1 - 0.11 12.6 9.5 2.8 8.2 0.0 6.0 5 1 1 6 6 6 0 Tetratricopeptide repeat THF_DHG_CYH PF00763.23 CDJ81251.1 - 0.12 12.6 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain TPR_19 PF14559.6 CDJ81251.1 - 0.32 11.5 14.5 4.2 7.9 1.1 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ81251.1 - 0.57 10.1 12.4 1.4 8.8 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ81251.1 - 1 9.7 22.0 2 8.7 0.0 6.2 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ81251.1 - 1.8 8.6 5.2 13 5.8 0.0 4.2 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 CDJ81251.1 - 6.8 7.6 9.7 19 6.3 0.4 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C2H2 PF00096.26 CDJ81252.1 - 0.0088 16.5 7.8 0.57 10.7 2.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 CDJ81252.1 - 0.018 14.6 5.3 0.14 11.8 0.2 2.4 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 CDJ81252.1 - 0.025 14.9 1.8 2.3 8.6 0.1 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 CDJ81252.1 - 0.028 14.9 5.7 0.63 10.6 0.6 3.3 3 0 0 3 3 3 0 Zinc-finger double domain Ribosomal_L37e PF01907.19 CDJ81252.1 - 0.059 13.5 1.2 6.2 7.1 0.1 2.5 2 0 0 2 2 2 0 Ribosomal protein L37e zf-H2C2_5 PF13909.6 CDJ81252.1 - 0.088 12.6 6.3 0.35 10.7 1.6 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-Di19 PF05605.12 CDJ81252.1 - 0.099 13.0 1.6 0.35 11.2 0.6 2.4 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 CDJ81252.1 - 0.21 12.5 5.8 0.76 10.8 2.0 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-piccolo PF05715.13 CDJ81252.1 - 0.33 11.1 4.9 2 8.6 0.2 3.0 2 1 0 3 3 3 0 Piccolo Zn-finger AKAP95 PF04988.12 CDJ81252.1 - 0.46 10.7 3.5 0.51 10.6 1.2 2.1 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) TANGO2 PF05742.12 CDJ81253.1 - 1.8e-42 146.1 0.0 2.3e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Yip1 PF04893.17 CDJ81254.1 - 3.8e-16 59.3 8.9 6e-16 58.6 8.9 1.3 1 0 0 1 1 1 1 Yip1 domain MFS_1 PF07690.16 CDJ81255.1 - 8e-41 140.1 25.5 8e-41 140.1 25.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 CDJ81256.1 - 1.6e-26 93.1 26.9 3.8e-22 78.7 6.3 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily Creatinase_N_2 PF16189.5 CDJ81257.1 - 2.1e-79 265.3 0.0 7.7e-39 133.4 0.0 3.5 4 0 0 4 4 4 2 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 CDJ81257.1 - 6.2e-74 248.2 0.3 8.1e-36 123.7 0.0 2.3 2 0 0 2 2 2 2 Metallopeptidase family M24 MFS_1 PF07690.16 CDJ81257.1 - 8.5e-46 156.5 28.4 8.5e-46 156.5 28.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Creatinase_N PF01321.18 CDJ81257.1 - 1.3e-25 90.6 0.3 7e-10 39.7 0.0 4.6 4 0 0 4 4 4 4 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 CDJ81257.1 - 6.2e-19 67.8 0.0 5.1e-08 32.9 0.0 2.9 2 0 0 2 2 2 2 C-terminal region of peptidase_M24 Plant_vir_prot PF01307.17 CDJ81257.1 - 0.07 13.4 0.0 76 3.6 0.0 3.7 3 0 0 3 3 3 0 Plant viral movement protein FimA PF16970.5 CDJ81257.1 - 0.071 13.3 0.0 16 5.7 0.0 2.6 2 0 0 2 2 2 0 Type-1 fimbrial protein, A Adap_comp_sub PF00928.21 CDJ81258.1 - 2.8e-90 302.3 0.1 4.1e-90 301.7 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CDJ81258.1 - 1.3e-08 34.9 1.5 2.3e-08 34.1 1.5 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Treslin_N PF15292.6 CDJ81259.1 - 0.036 12.4 3.0 0.045 12.1 3.0 1.0 1 0 0 1 1 1 0 Treslin N-terminus Ribosomal_L29 PF00831.23 CDJ81259.1 - 0.098 12.6 5.5 0.33 11.0 1.4 2.3 1 1 1 2 2 2 0 Ribosomal L29 protein Atg14 PF10186.9 CDJ81259.1 - 0.16 11.0 5.9 0.21 10.6 5.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RVT_1 PF00078.27 CDJ81260.1 - 1.7e-14 53.9 0.0 2.9e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF229 PF02995.17 CDJ81261.1 - 5.2e-06 25.4 0.2 7e-06 24.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF229 PF02995.17 CDJ81262.1 - 9.8e-77 258.6 1.5 1.3e-76 258.2 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 CDJ81262.1 - 0.0046 16.4 0.1 0.016 14.6 0.0 1.8 1 1 1 2 2 2 1 Sulfatase DUF229 PF02995.17 CDJ81263.1 - 3.8e-45 154.4 1.3 4.4e-45 154.2 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 CDJ81263.1 - 0.0013 18.2 0.1 0.0038 16.7 0.0 1.7 1 1 1 2 2 2 1 Sulfatase Glyoxalase PF00903.25 CDJ81263.1 - 0.036 14.2 0.0 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Lipase_GDSL PF00657.22 CDJ81264.1 - 4.7e-12 46.3 0.0 2.2e-11 44.1 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 CDJ81264.1 - 0.0082 16.6 0.1 0.044 14.2 0.1 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CUE PF02845.16 CDJ81264.1 - 0.12 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 CUE domain Pkinase PF00069.25 CDJ81265.1 - 1.1e-67 228.3 0.0 1.5e-67 227.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ81265.1 - 1.1e-29 103.6 0.0 1.5e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 CDJ81265.1 - 9.6e-29 99.8 4.4 4.6e-10 40.0 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ81265.1 - 2.7e-20 72.5 2.5 1.1e-08 35.4 0.1 3.8 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ81265.1 - 4.2e-17 62.0 2.4 3e-05 24.2 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ81265.1 - 1.4e-15 55.8 1.0 0.008 16.6 0.0 5.2 5 0 0 5 5 4 3 Ankyrin repeat Ank PF00023.30 CDJ81265.1 - 1e-12 47.9 4.4 0.00099 19.5 0.2 4.5 4 0 0 4 4 4 3 Ankyrin repeat Kdo PF06293.14 CDJ81265.1 - 1.3e-05 24.7 0.0 2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDJ81265.1 - 9.3e-05 21.4 0.0 0.00015 20.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDJ81265.1 - 0.00023 20.6 0.0 0.00049 19.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CDJ81265.1 - 0.00039 20.4 0.0 0.00091 19.2 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CDJ81265.1 - 0.0013 18.4 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.9 CDJ81265.1 - 0.026 14.0 0.1 0.07 12.6 0.1 1.7 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.11 CDJ81265.1 - 0.15 11.1 0.1 0.25 10.4 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Apo-CII PF05355.11 CDJ81266.1 - 0.14 12.3 0.0 3.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Apolipoprotein C-II DNA_pol_phi PF04931.13 CDJ81266.1 - 0.27 9.3 2.7 0.34 9.0 2.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi Ank_2 PF12796.7 CDJ81267.1 - 7.3e-25 87.4 8.4 1.5e-13 51.1 0.5 3.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ81267.1 - 5.5e-19 68.3 4.8 2.6e-10 40.6 0.5 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Death PF00531.22 CDJ81267.1 - 5.7e-19 68.1 0.1 1.2e-18 67.1 0.1 1.5 1 0 0 1 1 1 1 Death domain Ank_5 PF13857.6 CDJ81267.1 - 6.1e-17 61.5 8.1 8.9e-07 29.1 0.2 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ81267.1 - 8e-17 59.6 7.0 0.016 15.7 0.2 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 CDJ81267.1 - 1.8e-15 56.6 12.0 0.00038 20.8 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat TMEM215 PF15746.5 CDJ81268.1 - 0.14 11.6 1.2 0.23 10.9 0.9 1.5 1 1 1 2 2 2 0 TMEM215 family RHH_1 PF01402.21 CDJ81268.1 - 8.4 6.5 7.0 1.1 9.2 0.2 2.9 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family Ribosomal_L22 PF00237.19 CDJ81269.1 - 3.4e-41 139.6 0.1 5.1e-41 139.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Clat_adaptor_s PF01217.20 CDJ81270.1 - 2.2e-50 170.3 4.4 2.8e-50 170.0 4.4 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_L22 PF00237.19 CDJ81272.1 - 3.4e-41 139.6 0.1 5.1e-41 139.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Clat_adaptor_s PF01217.20 CDJ81273.1 - 2.2e-50 170.3 4.4 2.8e-50 170.0 4.4 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-C2H2 PF00096.26 CDJ81274.1 - 3.3e-06 27.2 45.8 0.044 14.3 1.6 6.9 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ81274.1 - 2.2e-05 24.9 48.2 0.037 14.9 0.5 7.9 8 1 0 8 8 8 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDJ81274.1 - 0.00024 21.4 38.0 0.026 15.0 0.5 7.5 7 1 0 7 7 7 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 CDJ81274.1 - 0.0058 16.6 1.4 0.0058 16.6 1.4 6.8 7 1 0 7 7 7 1 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 CDJ81274.1 - 0.026 14.4 23.2 0.053 13.4 0.2 5.6 4 3 0 4 4 4 0 SprT-like zinc ribbon domain zf-C2H2_8 PF15909.5 CDJ81274.1 - 0.15 12.4 20.5 0.11 12.8 3.1 3.5 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 CDJ81274.1 - 0.2 12.3 17.5 2.7 8.7 8.4 2.5 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 CDJ81274.1 - 3.3 7.4 28.0 1.2 8.8 0.0 7.0 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger Homeodomain PF00046.29 CDJ81276.1 - 3e-22 78.2 9.1 6.8e-22 77.1 8.8 1.7 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CDJ81276.1 - 0.0028 17.5 0.7 0.0054 16.6 0.7 1.5 1 0 0 1 1 1 1 Homeobox KN domain Trypsin PF00089.26 CDJ81279.1 - 7.8e-16 58.5 0.9 5.2e-07 29.7 0.3 2.3 1 1 1 2 2 2 2 Trypsin Trypsin_2 PF13365.6 CDJ81279.1 - 0.021 15.7 0.6 0.091 13.7 0.5 1.9 1 1 0 1 1 1 0 Trypsin-like peptidase domain Cadherin PF00028.17 CDJ81280.1 - 3.8e-110 360.6 10.1 1.1e-20 73.9 0.1 7.3 7 1 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 CDJ81280.1 - 4.1e-14 52.2 0.2 0.18 11.6 0.0 6.7 7 0 0 7 7 7 4 Cadherin-like Cadherin_3 PF16184.5 CDJ81280.1 - 4.8e-10 39.4 10.7 0.0012 18.8 0.1 6.1 6 0 0 6 6 6 2 Cadherin-like Cadherin_4 PF17803.1 CDJ81280.1 - 9.5e-07 29.4 21.2 0.21 12.3 0.0 5.6 5 0 0 5 5 5 4 Bacterial cadherin-like domain RET_CLD1 PF17756.1 CDJ81280.1 - 5.7e-06 26.6 0.0 5.3 7.3 0.0 5.6 6 1 0 6 6 6 2 RET Cadherin like domain 1 zf-C2H2 PF00096.26 CDJ81281.1 - 1.8e-15 56.4 29.9 9.4e-05 22.7 0.5 6.5 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ81281.1 - 4.4e-10 39.5 33.1 0.00097 19.8 0.1 6.5 6 0 0 6 6 6 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDJ81281.1 - 5.5e-10 39.2 34.1 4.7e-07 29.9 0.0 6.0 6 1 0 6 6 5 4 Zinc-finger double domain zf-C2H2_11 PF16622.5 CDJ81281.1 - 6.3e-08 32.2 15.0 0.00015 21.4 0.3 4.0 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-met PF12874.7 CDJ81281.1 - 5.4e-07 29.8 1.1 0.25 11.8 0.1 4.8 4 1 1 5 5 5 2 Zinc-finger of C2H2 type zf_UBZ PF18439.1 CDJ81281.1 - 2.2e-05 24.0 6.1 0.13 11.9 0.2 3.9 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 CDJ81281.1 - 4e-05 23.5 11.9 0.02 14.9 0.1 4.7 5 0 0 5 5 5 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 CDJ81281.1 - 0.00036 20.6 15.5 0.0091 16.1 0.7 4.4 3 1 1 4 4 4 1 Zinc ribbon domain ADK_lid PF05191.14 CDJ81281.1 - 0.00055 19.9 0.3 0.25 11.3 0.1 3.2 2 1 0 2 2 2 1 Adenylate kinase, active site lid zf-C2H2_jaz PF12171.8 CDJ81281.1 - 0.0039 17.4 16.3 0.097 13.0 0.1 5.6 6 0 0 6 6 5 2 Zinc-finger double-stranded RNA-binding XPA_N PF01286.18 CDJ81281.1 - 0.012 15.6 12.2 0.42 10.7 0.2 4.4 4 0 0 4 4 4 0 XPA protein N-terminal HNH_5 PF14279.6 CDJ81281.1 - 0.035 14.0 2.0 0.5 10.3 0.4 3.1 2 1 0 2 2 2 0 HNH endonuclease zf-C2H2_8 PF15909.5 CDJ81281.1 - 0.28 11.5 12.6 0.24 11.7 1.2 2.5 1 1 1 2 2 2 0 C2H2-type zinc ribbon FYVE PF01363.21 CDJ81281.1 - 0.38 10.9 16.8 2.1 8.5 9.7 3.3 2 1 0 2 2 2 0 FYVE zinc finger zf-C2H2_3rep PF18868.1 CDJ81281.1 - 0.56 10.9 14.4 0.18 12.5 2.3 3.8 2 1 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-AN1 PF01428.16 CDJ81281.1 - 0.58 10.4 14.5 25 5.2 0.1 4.8 4 1 0 4 4 4 0 AN1-like Zinc finger zf-TRAF PF02176.18 CDJ81281.1 - 0.61 10.8 16.1 4.4 8.1 4.3 3.6 2 1 1 3 3 3 0 TRAF-type zinc finger zf-trcl PF13451.6 CDJ81281.1 - 1.2 9.1 6.9 25 4.9 0.3 3.6 3 0 0 3 3 3 0 Probable zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 CDJ81281.1 - 1.3 9.1 6.0 67 3.6 3.2 3.4 2 1 0 2 2 2 0 PhnA Zinc-Ribbon zinc_ribbon_15 PF17032.5 CDJ81281.1 - 2.8 8.8 11.0 0.63 10.8 0.3 3.1 3 0 0 3 3 3 0 zinc-ribbon family zf-C2HE PF16278.5 CDJ81281.1 - 6.3 7.3 17.9 5 7.7 1.9 4.8 3 2 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger PDZ PF00595.24 CDJ81282.1 - 0.00067 20.0 0.2 0.007 16.7 0.1 2.2 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 CDJ81282.1 - 0.0052 16.6 0.0 0.91 9.4 0.0 2.7 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 CDJ81282.1 - 0.11 12.5 0.0 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Tricorn protease PDZ domain HZS_alpha PF18582.1 CDJ81282.1 - 0.18 12.3 0.0 0.4 11.2 0.0 1.5 1 0 0 1 1 1 0 Hydrazine synthase alpha subunit middle domain LSM PF01423.22 CDJ81283.1 - 9.2e-22 76.5 0.0 1.2e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CDJ81283.1 - 0.0065 16.6 0.0 0.0093 16.1 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain RNase_Zc3h12a_2 PF14626.6 CDJ81284.1 - 1.5e-16 60.7 0.1 5.5e-14 52.4 0.1 2.6 2 1 1 3 3 3 2 Zc3h12a-like Ribonuclease NYN domain RNase_Zc3h12a PF11977.8 CDJ81284.1 - 4.2e-08 33.1 0.0 7.2e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PIF1 PF05970.14 CDJ81285.1 - 5.4e-48 164.0 5.5 3.2e-37 128.6 0.2 3.0 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 CDJ81285.1 - 2.1e-21 76.5 0.0 3.1e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ81285.1 - 5.2e-08 33.3 0.0 1.5e-07 31.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 CDJ81285.1 - 0.00011 20.3 0.3 0.05 11.5 0.0 2.2 2 0 0 2 2 2 2 Helicase UvrD_C_2 PF13538.6 CDJ81285.1 - 0.00021 21.0 0.0 0.00053 19.8 0.0 1.7 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_7 PF12775.7 CDJ81285.1 - 0.00085 18.9 0.0 0.0021 17.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 CDJ81285.1 - 0.0014 18.1 0.0 0.0031 16.9 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 CDJ81285.1 - 0.0021 17.9 0.5 0.39 10.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 CDJ81285.1 - 0.0038 16.3 0.0 0.0066 15.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 CDJ81285.1 - 0.0064 16.9 0.1 0.019 15.4 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDJ81285.1 - 0.016 15.5 0.1 0.058 13.7 0.0 2.0 2 1 0 2 2 1 0 AAA domain AAA_5 PF07728.14 CDJ81285.1 - 0.023 14.7 0.1 0.098 12.7 0.0 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CDJ81285.1 - 0.043 13.5 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF2075 PF09848.9 CDJ81285.1 - 0.069 12.4 0.1 0.4 9.9 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 CDJ81285.1 - 0.084 12.3 0.0 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Arv1 PF04161.13 CDJ81286.1 - 1.5e-26 93.9 8.9 5.6e-26 92.0 8.9 1.7 1 1 0 1 1 1 1 Arv1-like family Gal-bind_lectin PF00337.22 CDJ81287.1 - 7.5e-72 239.2 0.0 8.5e-37 125.7 0.0 2.0 2 0 0 2 2 2 2 Galactoside-binding lectin SBDS PF01172.18 CDJ81287.1 - 0.058 13.5 0.2 0.5 10.5 0.0 2.4 2 1 0 2 2 2 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein An_peroxidase PF03098.15 CDJ81289.1 - 4.4e-23 81.6 0.0 6.4e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase ShK PF01549.24 CDJ81289.1 - 2e-07 31.4 10.5 6.5e-07 29.8 10.5 1.8 1 0 0 1 1 1 1 ShK domain-like KLRAQ PF10205.9 CDJ81291.1 - 1.3e-21 76.7 6.1 1.3e-21 76.7 6.1 3.8 2 1 1 3 3 3 1 Predicted coiled-coil domain-containing protein TTKRSYEDQ PF10212.9 CDJ81291.1 - 9.5e-18 64.5 27.6 3.4e-11 42.9 5.1 3.6 3 1 1 4 4 4 2 Predicted coiled-coil domain-containing protein MBOAT PF03062.19 CDJ81291.1 - 4.3e-12 46.0 7.5 1.9e-10 40.7 7.5 2.2 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family CLTH PF10607.9 CDJ81291.1 - 1.9e-07 31.1 0.0 8.4e-07 29.0 0.0 2.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain PGM_PMM_III PF02880.16 CDJ81291.1 - 0.0003 21.0 0.1 0.0011 19.1 0.1 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DUF4668 PF15701.5 CDJ81291.1 - 0.0057 16.5 2.2 0.024 14.4 0.2 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4668) DUF3450 PF11932.8 CDJ81291.1 - 0.0064 15.8 1.0 0.0064 15.8 1.0 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3450) FlxA PF14282.6 CDJ81291.1 - 0.0099 15.8 4.4 1.5 8.9 0.0 4.3 3 1 1 4 4 4 1 FlxA-like protein Baculo_PEP_C PF04513.12 CDJ81291.1 - 0.021 14.8 16.1 0.99 9.4 0.0 6.3 5 1 2 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus LisH PF08513.11 CDJ81291.1 - 0.037 14.0 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 LisH DUF4972 PF16342.5 CDJ81291.1 - 0.038 13.7 3.6 0.17 11.6 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4972) DASH_Dad4 PF08650.10 CDJ81291.1 - 0.12 12.4 10.4 14 5.7 0.9 5.3 5 0 0 5 5 5 0 DASH complex subunit Dad4 DUF4407 PF14362.6 CDJ81291.1 - 3 7.1 14.7 7.5 5.8 5.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SlyX PF04102.12 CDJ81291.1 - 3.5 8.3 20.8 1.7 9.3 0.2 6.3 6 1 0 6 6 5 0 SlyX Prominin PF05478.11 CDJ81291.1 - 4.4 5.1 16.6 1.6 6.6 5.9 3.0 3 0 0 3 3 3 0 Prominin DivIC PF04977.15 CDJ81291.1 - 6.1 6.7 22.3 0.028 14.2 1.6 4.8 4 2 1 5 5 5 0 Septum formation initiator End3 PF12761.7 CDJ81291.1 - 8.4 6.5 15.4 1.2 9.3 7.4 2.7 2 1 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Requiem_N PF14051.6 CDJ81292.1 - 0.0033 17.6 0.0 0.0093 16.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. Rnk_N PF14760.6 CDJ81292.1 - 0.0048 17.4 0.1 0.12 12.9 0.0 2.6 2 0 0 2 2 2 1 Rnk N-terminus Chromo_2 PF18704.1 CDJ81292.1 - 0.064 13.5 0.0 0.22 11.8 0.0 2.0 1 0 0 1 1 1 0 Chromatin organization modifier domain 2 TIP120 PF08623.10 CDJ81292.1 - 0.08 12.7 2.2 0.13 12.0 2.2 1.3 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) ABC_tran_Xtn PF12848.7 CDJ81292.1 - 0.39 10.8 12.2 0.049 13.7 7.3 2.1 2 0 0 2 2 2 0 ABC transporter LMBR1 PF04791.16 CDJ81292.1 - 1.4 7.7 2.6 1.8 7.4 2.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Complex1_LYR_2 PF13233.6 CDJ81293.1 - 1.4e-16 61.0 0.0 2.6e-16 60.1 0.0 1.6 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 CDJ81293.1 - 2.3e-06 27.5 0.0 4.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) HTH_psq PF05225.16 CDJ81294.1 - 5.8e-08 32.4 0.0 1.4e-07 31.2 0.0 1.6 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 CDJ81294.1 - 0.052 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_5 PF01022.20 CDJ81294.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family zf-HC5HC2H_2 PF13832.6 CDJ81295.1 - 6e-18 65.0 2.0 6e-18 65.0 2.0 3.4 3 0 0 3 3 3 1 PHD-zinc-finger like domain PHD PF00628.29 CDJ81295.1 - 5.8e-11 42.1 45.3 1.1e-06 28.5 15.8 4.3 4 0 0 4 4 4 2 PHD-finger zf-HC5HC2H PF13771.6 CDJ81295.1 - 4.8e-10 39.6 1.5 4.8e-10 39.6 1.5 3.9 4 0 0 4 4 4 1 PHD-like zinc-binding domain C1_1 PF00130.22 CDJ81295.1 - 0.00022 21.0 34.0 0.00027 20.8 0.7 4.6 4 1 1 5 5 5 3 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 CDJ81295.1 - 0.001 18.6 4.9 0.001 18.6 4.9 4.7 4 1 0 4 4 4 1 PHD-finger Prok-RING_1 PF14446.6 CDJ81295.1 - 3 7.8 23.9 0.56 10.2 2.2 4.4 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 Ion_trans_2 PF07885.16 CDJ81297.1 - 1.6e-38 130.5 8.1 9.4e-19 67.2 0.3 2.5 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 CDJ81297.1 - 1.2e-07 31.2 6.2 0.0003 20.1 0.3 2.2 2 0 0 2 2 2 2 Ion transport protein IRK PF01007.20 CDJ81297.1 - 0.027 14.3 0.1 0.075 12.8 0.1 1.8 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain Glyco_transf_92 PF01697.27 CDJ81298.1 - 1.8e-48 165.4 0.0 2.4e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 92 Neur_chan_LBD PF02931.23 CDJ81300.1 - 1.3e-37 129.4 0.3 2.2e-37 128.6 0.3 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ81300.1 - 5.3e-34 118.3 4.6 7.8e-28 98.1 1.9 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Prd1-P2 PF09214.11 CDJ81300.1 - 0.0091 14.8 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 1 Bacteriophage Prd1, adsorption protein P2 RVT_1 PF00078.27 CDJ81301.1 - 5.8e-31 107.7 0.0 1.1e-30 106.8 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SLC12 PF03522.15 CDJ81303.1 - 4.6e-09 35.8 0.1 4.6e-09 35.8 0.1 1.7 1 1 0 2 2 2 1 Solute carrier family 12 Transposase_1 PF01359.18 CDJ81304.1 - 2.6e-16 59.2 0.8 5.2e-16 58.2 0.1 2.0 2 0 0 2 2 2 1 Transposase (partial DDE domain) SLC12 PF03522.15 CDJ81304.1 - 1.2e-14 54.2 0.1 1.7e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 Solute carrier family 12 DUF2255 PF10012.9 CDJ81304.1 - 0.091 12.9 0.2 13 6.0 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2255) RVT_1 PF00078.27 CDJ81305.1 - 5.5e-06 26.1 0.1 5.8e-06 26.0 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribo_biogen_C PF04034.13 CDJ81307.1 - 1.4e-49 167.0 0.0 1.7e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 CDJ81307.1 - 3.3e-10 39.6 0.0 5.5e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI WD40 PF00400.32 CDJ81308.1 - 3.2e-44 148.0 32.5 4.5e-08 33.6 1.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 CDJ81308.1 - 1.6e-10 40.7 5.8 1.6e-10 40.7 5.8 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CDJ81308.1 - 2.7e-08 33.5 4.3 6.4e-08 32.3 4.3 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 CDJ81308.1 - 1.5e-07 30.5 17.3 0.0019 16.9 0.1 5.8 1 1 5 6 6 6 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CDJ81308.1 - 2.5e-06 27.7 4.5 0.096 13.0 0.1 5.6 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 CDJ81308.1 - 1.3e-05 25.0 2.5 2.2e-05 24.3 0.2 2.4 2 1 0 2 2 2 1 F-box WD40_like PF17005.5 CDJ81308.1 - 0.0035 16.7 0.4 0.19 11.1 0.0 3.0 1 1 1 3 3 3 1 WD40-like domain HARP PF07443.13 CDJ81308.1 - 0.021 14.4 0.4 7.3 6.3 0.1 3.5 4 0 0 4 4 4 0 HepA-related protein (HARP) Mcl1_mid PF12341.8 CDJ81308.1 - 0.037 13.4 0.6 1.4 8.2 0.0 2.6 1 1 1 3 3 3 0 Minichromosome loss protein, Mcl1, middle region GPS PF01825.21 CDJ81308.1 - 0.4 11.2 0.2 0.4 11.2 0.2 3.6 4 1 0 4 4 4 0 GPCR proteolysis site, GPS, motif Phi-29_GP3 PF05435.11 CDJ81311.1 - 0.026 14.0 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 Sre PF03125.18 CDJ81312.1 - 4.1e-13 49.2 9.7 4.8e-13 49.0 9.7 1.1 1 0 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor 7TM_GPCR_Srab PF10292.9 CDJ81312.1 - 4e-07 29.3 9.9 2.9e-06 26.5 9.9 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor 3Beta_HSD PF01073.19 CDJ81313.1 - 4.8e-41 140.6 0.0 6.2e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CDJ81313.1 - 1.3e-21 77.2 0.0 1.7e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CDJ81313.1 - 5.7e-07 28.9 0.0 8.2e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 CDJ81313.1 - 6.2e-07 29.1 0.0 8.9e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CDJ81313.1 - 4.3e-06 26.1 0.0 1e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 CDJ81313.1 - 5.9e-05 23.0 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CDJ81313.1 - 0.00023 20.4 0.1 0.00084 18.6 0.0 1.8 1 1 1 2 2 2 1 Male sterility protein KR PF08659.10 CDJ81313.1 - 0.013 15.5 0.4 3.9 7.3 0.2 2.4 2 0 0 2 2 2 0 KR domain RVT_1 PF00078.27 CDJ81314.1 - 3.2e-25 89.0 0.0 5.8e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDJ81316.1 - 1.7e-36 124.2 0.0 4.1e-36 123.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ81316.1 - 9.2e-33 112.7 0.0 7.3e-32 109.8 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ81316.1 - 1.2e-22 80.4 0.0 3.7e-22 78.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ81316.1 - 1.1e-17 63.9 0.6 2.2e-17 62.9 0.1 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 CDJ81316.1 - 5.8e-09 35.8 0.0 1.8e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 CDJ81316.1 - 7.2e-05 22.5 0.0 0.00022 21.0 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CDJ81316.1 - 0.036 14.3 0.0 0.082 13.1 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger DnaJ PF00226.31 CDJ81317.1 - 4.6e-14 52.3 1.1 7.8e-14 51.6 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1242 PF06842.12 CDJ81317.1 - 3.1e-12 46.1 0.7 5.6e-12 45.3 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DUF2462 PF09495.10 CDJ81317.1 - 1.4e-10 41.7 9.9 2.6e-10 40.9 9.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) Nup54 PF13874.6 CDJ81318.1 - 8.5e-33 113.4 2.4 8.5e-33 113.4 2.4 3.0 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 CDJ81318.1 - 8.6e-10 39.3 67.5 1.7e-07 32.0 33.6 3.1 2 1 1 3 3 3 2 Nucleoporin FG repeat region TBCC PF07986.12 CDJ81323.1 - 8.2e-33 112.7 6.2 3.1e-32 110.8 4.5 2.2 2 0 0 2 2 2 1 Tubulin binding cofactor C CAP_C PF08603.11 CDJ81323.1 - 4.2e-06 26.5 0.3 2.2e-05 24.1 0.1 2.0 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal zf-CCHC PF00098.23 CDJ81324.1 - 1.9e-37 125.7 51.6 5.6e-09 35.7 3.9 5.2 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ81324.1 - 7.5e-07 29.0 36.6 0.014 15.3 1.5 5.1 2 2 3 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ81324.1 - 0.00022 20.9 29.8 0.037 13.8 0.8 5.1 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_5 PF14787.6 CDJ81324.1 - 0.0016 18.1 32.5 0.87 9.3 1.0 5.1 5 0 0 5 5 5 5 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 CDJ81324.1 - 0.84 9.5 43.3 0.77 9.6 1.3 5.5 5 0 0 5 5 5 0 Zinc knuckle Proteasome PF00227.26 CDJ81325.1 - 3.1e-45 154.0 0.1 3.6e-45 153.8 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit RRM_1 PF00076.22 CDJ81327.1 - 9.6e-23 79.8 0.0 1.1e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ81327.1 - 0.0036 16.9 0.0 0.0037 16.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ81327.1 - 0.015 15.2 0.0 0.032 14.1 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif Pyr_redox_dim PF02852.22 CDJ81327.1 - 0.041 14.2 0.0 0.044 14.0 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain RRM_1 PF00076.22 CDJ81328.1 - 7.4e-22 76.9 0.0 8.5e-22 76.8 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ81328.1 - 0.02 14.8 0.0 0.043 13.7 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_5 PF13893.6 CDJ81328.1 - 0.029 14.0 0.0 0.029 13.9 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pyr_redox_dim PF02852.22 CDJ81328.1 - 0.04 14.2 0.0 0.044 14.1 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SH2 PF00017.24 CDJ81329.1 - 0.0039 17.3 0.0 0.033 14.3 0.0 2.4 3 0 0 3 3 3 1 SH2 domain OCIA PF07051.11 CDJ81329.1 - 0.025 14.6 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Ovarian carcinoma immunoreactive antigen (OCIA) Pkinase_Tyr PF07714.17 CDJ81330.1 - 4.7e-39 134.2 0.0 6.5e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ81330.1 - 2.7e-20 72.8 0.0 3.7e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain CBFD_NFYB_HMF PF00808.23 CDJ81331.1 - 9.7e-14 51.4 0.1 1.7e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 CDJ81331.1 - 0.00028 20.9 0.1 0.00038 20.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 CDJ81331.1 - 0.00079 19.8 0.4 0.0015 18.9 0.1 1.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 CDJ81331.1 - 0.034 14.2 0.0 0.061 13.4 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit VPS13 PF16908.5 CDJ81331.1 - 0.035 13.9 0.0 0.043 13.6 0.0 1.0 1 0 0 1 1 1 0 Vacuolar sorting-associated protein 13, N-terminal Transposase_1 PF01359.18 CDJ81332.1 - 1.3e-23 82.6 0.5 2.7e-23 81.6 0.2 1.8 2 0 0 2 2 2 1 Transposase (partial DDE domain) HTH_48 PF17906.1 CDJ81332.1 - 4.8e-16 58.6 0.0 1.5e-15 57.0 0.0 1.9 2 0 0 2 2 1 1 HTH domain in Mos1 transposase DDE_3 PF13358.6 CDJ81332.1 - 9.1e-12 44.9 0.0 1.3e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 CDJ81332.1 - 5.1e-06 26.6 0.1 0.00036 20.7 0.0 3.1 3 0 0 3 3 3 1 Transposase HTH_32 PF13565.6 CDJ81332.1 - 2.4e-05 24.8 0.0 8.2e-05 23.1 0.0 2.0 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 CDJ81332.1 - 3e-05 23.7 0.5 0.057 13.2 0.1 2.8 3 0 0 3 3 2 2 Homeodomain-like domain HTH_29 PF13551.6 CDJ81332.1 - 0.00037 20.5 0.1 0.033 14.2 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn helix HTH_11 PF08279.12 CDJ81332.1 - 0.00097 19.0 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_Tnp_IS630 PF01710.16 CDJ81332.1 - 0.0026 17.8 0.0 0.22 11.6 0.0 2.4 2 0 0 2 2 2 1 Transposase HTH_AsnC-type PF13404.6 CDJ81332.1 - 0.0044 16.8 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR PF01047.22 CDJ81332.1 - 0.0051 16.7 0.0 0.066 13.1 0.1 2.4 2 0 0 2 2 2 1 MarR family HTH_Tnp_4 PF13613.6 CDJ81332.1 - 0.0075 16.0 0.9 4.1 7.2 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease HTH_24 PF13412.6 CDJ81332.1 - 0.012 15.2 0.2 0.031 13.8 0.2 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Phage_CI_repr PF07022.13 CDJ81332.1 - 0.012 15.7 0.2 0.14 12.2 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain HTH_10 PF04967.12 CDJ81332.1 - 0.016 15.0 0.0 0.053 13.3 0.0 1.8 2 0 0 2 2 2 0 HTH DNA binding domain HTH_28 PF13518.6 CDJ81332.1 - 0.021 15.0 1.2 0.22 11.7 0.6 2.7 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_50 PF18024.1 CDJ81332.1 - 0.026 14.1 0.3 0.074 12.7 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_38 PF13936.6 CDJ81332.1 - 0.052 13.3 0.9 0.66 9.8 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 CDJ81332.1 - 0.059 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_7 PF02796.15 CDJ81332.1 - 0.064 13.3 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_Crp_2 PF13545.6 CDJ81332.1 - 0.1 12.6 0.1 0.9 9.6 0.1 2.4 1 1 2 3 3 3 0 Crp-like helix-turn-helix domain HTH_20 PF12840.7 CDJ81332.1 - 0.1 12.7 0.1 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Mga PF08280.11 CDJ81332.1 - 0.16 12.0 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Sigma70_r4_2 PF08281.12 CDJ81332.1 - 1.6 8.5 3.5 12 5.6 0.0 3.5 4 1 0 4 4 4 0 Sigma-70, region 4 Paramyxo_ncap PF00973.19 CDJ81333.1 - 4 6.3 9.6 4.8 6.0 9.6 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein RINT1_TIP1 PF04437.13 CDJ81334.1 - 2.4e-35 122.4 1.4 4e-35 121.7 0.1 1.8 2 0 0 2 2 2 1 RINT-1 / TIP-1 family CENP-Q PF13094.6 CDJ81335.1 - 0.058 13.6 2.9 0.093 12.9 2.8 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit RVT_N PF13655.6 CDJ81335.1 - 0.067 13.5 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 N-terminal domain of reverse transcriptase CwfJ_C_2 PF04676.14 CDJ81336.1 - 2.3e-28 99.0 0.4 4.1e-28 98.2 0.2 1.5 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 AbiEi_3 PF11459.8 CDJ81336.1 - 0.027 14.2 0.0 1.9 8.1 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Tubulin-binding PF00418.19 CDJ81336.1 - 0.13 12.3 1.7 0.29 11.2 0.9 1.9 2 0 0 2 2 2 0 Tau and MAP protein, tubulin-binding repeat RRM_1 PF00076.22 CDJ81337.1 - 8.9e-21 73.5 0.0 1.3e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ81337.1 - 0.0052 16.6 0.0 0.01 15.7 0.0 1.4 1 1 0 1 1 1 1 Occluded RNA-recognition motif DUF4602 PF15375.6 CDJ81338.1 - 9.5e-12 45.4 7.9 1.2e-11 45.1 7.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4602) PerB PF06590.11 CDJ81338.1 - 0.11 13.1 0.0 0.27 11.8 0.0 1.6 1 0 0 1 1 1 0 PerB protein Phage_int_SAM_4 PF13495.6 CDJ81339.1 - 0.11 12.9 0.9 0.16 12.5 0.9 1.2 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain XPG_I PF00867.18 CDJ81340.1 - 1.5e-23 82.9 0.0 5e-23 81.3 0.0 2.0 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CDJ81340.1 - 3.9e-21 75.4 0.0 9.7e-21 74.2 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain BTB PF00651.31 CDJ81341.1 - 1.3e-12 47.9 1.1 6.8e-11 42.4 1.1 2.2 1 1 0 1 1 1 1 BTB/POZ domain HSP90 PF00183.18 CDJ81342.1 - 2e-11 43.5 12.2 0.00031 19.8 3.0 3.1 1 1 2 3 3 3 3 Hsp90 protein HATPase_c_3 PF13589.6 CDJ81342.1 - 1.1e-10 41.4 0.1 2e-10 40.6 0.1 1.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDJ81342.1 - 1.8e-06 28.4 0.1 2.6e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_16 PF13432.6 CDJ81343.1 - 4.5e-20 72.0 0.3 0.0019 18.8 0.0 8.9 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ81343.1 - 4.1e-19 68.8 37.8 0.00013 22.4 0.3 12.8 10 3 4 14 14 13 4 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ81343.1 - 9.9e-16 57.1 21.2 0.019 15.8 0.1 11.2 9 3 3 12 12 11 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ81343.1 - 4.4e-14 52.5 12.3 0.02 15.1 0.1 9.5 8 2 2 10 10 10 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CDJ81343.1 - 1.2e-12 47.9 18.5 0.037 14.3 0.1 9.2 8 2 1 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ81343.1 - 2.5e-09 36.5 4.3 0.00081 19.3 0.0 6.9 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ81343.1 - 7.9e-09 35.1 12.3 0.011 15.9 0.1 8.7 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ81343.1 - 8.3e-09 35.5 24.1 1 10.1 0.1 12.4 15 0 0 15 15 13 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ81343.1 - 7.6e-08 31.9 21.3 0.024 14.7 0.0 10.5 13 0 0 13 13 9 2 Tetratricopeptide repeat TPR_15 PF13429.6 CDJ81343.1 - 8.4e-06 25.2 11.5 0.003 16.8 0.9 6.0 4 1 2 7 7 7 3 Tetratricopeptide repeat TPR_21 PF09976.9 CDJ81343.1 - 1.3e-05 25.0 17.6 8.5e-05 22.3 1.1 6.0 5 2 1 6 6 6 1 Tetratricopeptide repeat-like domain NARP1 PF12569.8 CDJ81343.1 - 1.3e-05 24.3 2.4 0.3 10.0 0.0 3.8 3 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_1 PF00515.28 CDJ81343.1 - 9.8e-05 22.0 20.8 0.00091 18.9 0.0 8.8 10 0 0 10 10 9 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CDJ81343.1 - 0.00014 21.5 1.5 0.02 14.6 0.1 4.1 3 1 0 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_17 PF13431.6 CDJ81343.1 - 0.00015 21.9 7.1 0.58 10.7 0.0 7.7 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_4 PF07721.14 CDJ81343.1 - 0.00029 21.2 6.1 0.95 10.3 0.0 6.9 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ81343.1 - 0.0031 17.2 2.6 0.19 11.4 0.0 5.0 6 0 0 6 6 5 1 TPR repeat FAT PF02259.23 CDJ81343.1 - 0.006 15.8 1.5 0.093 11.9 0.0 3.2 3 1 1 4 4 4 1 FAT domain TPR_10 PF13374.6 CDJ81343.1 - 0.012 15.4 10.8 0.79 9.7 0.0 7.3 10 0 0 10 10 10 0 Tetratricopeptide repeat SNAP PF14938.6 CDJ81343.1 - 0.025 14.0 2.7 1.6 8.0 0.3 3.9 3 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_9 PF13371.6 CDJ81343.1 - 0.031 14.4 4.2 5.3 7.3 0.0 5.3 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_5 PF12688.7 CDJ81343.1 - 0.05 13.8 8.5 1.3 9.3 0.0 4.7 5 1 1 6 6 5 0 Tetratrico peptide repeat LppC PF04348.13 CDJ81343.1 - 0.1 11.4 6.6 0.69 8.6 0.1 3.2 5 0 0 5 5 5 0 LppC putative lipoprotein ChAPs PF09295.10 CDJ81343.1 - 0.12 11.4 1.5 1.4 7.8 0.1 2.8 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Ribonuc_red_lgC PF02867.15 CDJ81344.1 - 2.7e-192 640.0 0.0 3.4e-192 639.7 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CDJ81344.1 - 1e-25 89.5 0.0 3e-25 88.0 0.0 1.9 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CDJ81344.1 - 2.4e-17 63.3 0.1 8.7e-17 61.5 0.1 2.0 1 0 0 1 1 1 1 ATP cone domain Shisa PF13908.6 CDJ81345.1 - 0.015 15.5 2.8 0.57 10.4 0.0 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator COG2 PF06148.11 CDJ81346.1 - 0.016 15.3 0.8 1.2 9.2 0.4 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2777 PF10949.8 CDJ81346.1 - 0.027 14.2 0.1 0.047 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) FA_desaturase PF00487.24 CDJ81346.1 - 0.35 10.7 3.4 3.3 7.5 1.3 2.1 2 0 0 2 2 2 0 Fatty acid desaturase RhodobacterPufX PF11511.8 CDJ81346.1 - 0.38 10.4 4.4 1.2 8.8 4.4 1.8 1 0 0 1 1 1 0 Intrinsic membrane protein PufX DinB_2 PF12867.7 CDJ81348.1 - 0.1 13.1 1.9 0.17 12.4 0.1 2.0 1 1 0 2 2 2 0 DinB superfamily Exo_endo_phos_2 PF14529.6 CDJ81349.1 - 0.018 14.9 0.0 0.052 13.4 0.0 1.9 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Sre PF03125.18 CDJ81350.1 - 8.5e-33 114.0 27.3 2.9e-31 109.0 27.3 2.1 1 1 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor 7TM_GPCR_Srab PF10292.9 CDJ81350.1 - 3.4e-07 29.5 19.9 5.1e-07 28.9 19.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor DUF5313 PF17240.2 CDJ81350.1 - 0.62 10.5 2.7 2.5 8.6 0.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5313) Sre PF03125.18 CDJ81351.1 - 2.4e-14 53.3 15.6 2.5e-12 46.6 15.6 2.2 1 1 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor 7TM_GPCR_Srab PF10292.9 CDJ81351.1 - 0.24 10.3 14.2 1.1 8.1 7.8 2.1 1 1 1 2 2 2 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor TFIIE_alpha PF02002.17 CDJ81354.1 - 2.3e-17 62.8 4.9 5.1e-17 61.7 4.9 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 CDJ81354.1 - 3e-13 49.9 5.6 7.6e-13 48.6 5.6 1.7 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.12 CDJ81354.1 - 0.00081 18.9 0.3 0.022 14.3 0.3 2.5 1 1 0 1 1 1 1 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 CDJ81354.1 - 0.0067 16.5 0.5 0.012 15.7 0.5 1.4 1 0 0 1 1 1 1 Zinc ribbon domain zf-C2HE PF16278.5 CDJ81354.1 - 0.0078 16.6 0.4 2.5 8.6 0.1 2.8 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger HypA PF01155.19 CDJ81354.1 - 0.026 14.6 0.1 0.05 13.6 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RNA_POL_M_15KD PF02150.16 CDJ81354.1 - 0.15 11.9 0.7 0.42 10.5 0.7 1.7 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit Elf1 PF05129.13 CDJ81354.1 - 0.18 11.9 0.6 0.71 10.0 0.6 1.9 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like TetR_C_37 PF18665.1 CDJ81354.1 - 0.24 12.0 2.8 0.36 11.5 2.0 1.6 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain zf-HIT PF04438.16 CDJ81354.1 - 4.4 7.3 4.5 0.49 10.3 0.4 1.5 2 0 0 2 2 2 0 HIT zinc finger Peptidase_M3 PF01432.20 CDJ81355.1 - 2.6e-102 343.5 0.0 3.9e-102 342.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 SH3_2 PF07653.17 CDJ81356.1 - 4.8e-07 29.4 0.0 9e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDJ81356.1 - 3.1e-06 26.7 0.0 5.9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Guanylate_kin PF00625.21 CDJ81356.1 - 0.029 14.0 0.2 2.2 8.0 0.0 2.6 3 0 0 3 3 3 0 Guanylate kinase SH3_9 PF14604.6 CDJ81356.1 - 0.16 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain HMG_box PF00505.19 CDJ81357.1 - 1.4e-17 63.9 7.0 3e-17 62.8 7.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ81357.1 - 2.5e-10 40.8 4.1 2.5e-10 40.8 4.1 1.9 2 0 0 2 2 2 1 HMG-box domain La PF05383.17 CDJ81358.1 - 5.7e-19 67.9 0.2 9.7e-19 67.2 0.2 1.4 1 0 0 1 1 1 1 La domain EstA_Ig_like PF18435.1 CDJ81359.1 - 0.065 13.4 0.3 0.11 12.6 0.3 1.3 1 0 0 1 1 1 0 Esterase Ig-like N-terminal domain Innexin PF00876.18 CDJ81360.1 - 1e-39 136.8 2.2 1.2e-39 136.7 2.2 1.0 1 0 0 1 1 1 1 Innexin Clavanin PF05452.11 CDJ81360.1 - 0.033 14.4 0.0 0.14 12.3 0.0 1.9 1 1 1 2 2 2 0 Clavanin Ig_mannosidase PF17753.1 CDJ81361.1 - 6.1e-07 29.1 0.1 1.5e-06 27.9 0.1 1.7 2 0 0 2 2 2 1 Ig-fold domain Sarcoglycan_1 PF04790.13 CDJ81362.1 - 3.4e-61 206.9 0.2 3.9e-61 206.7 0.2 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DNA_pol3_beta PF00712.19 CDJ81362.1 - 0.021 14.9 0.1 0.067 13.3 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase III beta subunit, N-terminal domain CAP_GLY PF01302.25 CDJ81363.1 - 1e-18 67.1 1.1 1.7e-18 66.3 1.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain GWT1 PF06423.12 CDJ81364.1 - 0.0074 16.4 0.1 0.0089 16.2 0.1 1.1 1 0 0 1 1 1 1 GWT1 Neur_chan_memb PF02932.16 CDJ81366.1 - 1.4e-30 107.1 9.5 2.1e-25 90.2 5.8 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CDJ81366.1 - 6.5e-27 94.4 0.1 9.3e-27 93.9 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF2417 PF10329.9 CDJ81366.1 - 0.13 11.6 5.0 1 8.7 5.0 2.0 1 1 0 1 1 1 0 Region of unknown function (DUF2417) SelR PF01641.18 CDJ81367.1 - 2.5e-50 169.6 0.4 3.1e-50 169.3 0.4 1.1 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 CDJ81367.1 - 0.022 14.9 1.3 0.045 14.0 1.3 1.6 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_10 PF10058.9 CDJ81367.1 - 0.029 14.1 2.8 0.35 10.6 0.1 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein HECT_2 PF09814.9 CDJ81367.1 - 0.047 12.5 0.2 0.2 10.5 0.0 1.8 2 0 0 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Ribosomal_L37e PF01907.19 CDJ81367.1 - 0.072 13.3 1.0 0.072 13.3 1.0 2.6 3 0 0 3 3 3 0 Ribosomal protein L37e RED_N PF07808.13 CDJ81368.1 - 3e-72 243.0 8.0 3e-72 243.0 8.0 3.6 1 1 1 2 2 2 1 RED-like protein N-terminal region RED_C PF07807.11 CDJ81368.1 - 7.9e-35 119.7 5.1 7.9e-35 119.7 5.1 4.5 3 1 0 3 3 3 1 RED-like protein C-terminal region Guanylate_cyc PF00211.20 CDJ81371.1 - 1.1e-57 194.6 0.0 1.4e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 CDJ81372.1 - 6.2e-49 166.4 0.7 8.7e-49 165.9 0.7 1.2 1 0 0 1 1 1 1 Heme NO binding associated HNOB PF07700.15 CDJ81372.1 - 2.5e-25 89.3 0.0 4.8e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Haem-NO-binding Glyco_tran_28_C PF04101.16 CDJ81372.1 - 0.087 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain AAA_16 PF13191.6 CDJ81374.1 - 0.008 16.6 0.2 0.013 15.8 0.2 1.4 1 0 0 1 1 1 1 AAA ATPase domain Tub PF01167.18 CDJ81374.1 - 0.046 13.5 0.2 0.064 13.0 0.2 1.3 1 0 0 1 1 1 0 Tub family DUF3629 PF12302.8 CDJ81375.1 - 0.0027 17.2 0.2 0.0053 16.2 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3629) Neur_chan_LBD PF02931.23 CDJ81376.1 - 2.6e-42 144.7 0.4 3.3e-42 144.4 0.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ81376.1 - 8.5e-23 81.6 5.0 1.2e-19 71.3 0.6 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Vinculin PF01044.19 CDJ81377.1 - 2.2e-71 241.4 7.2 1.9e-36 125.8 0.9 3.0 2 1 1 3 3 3 3 Vinculin family NLE PF08154.12 CDJ81377.1 - 0.071 13.6 0.1 1.5 9.4 0.0 2.7 2 0 0 2 2 2 0 NLE (NUC135) domain Cytochrom_C_2 PF01322.20 CDJ81377.1 - 0.099 13.5 1.1 1.1 10.1 0.9 2.6 2 0 0 2 2 2 0 Cytochrome C' ENT PF03735.14 CDJ81377.1 - 0.12 12.5 0.2 0.33 11.1 0.2 1.7 1 0 0 1 1 1 0 ENT domain DUF4217 PF13959.6 CDJ81379.1 - 3.5e-13 49.6 0.2 6.3e-13 48.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 CDJ81379.1 - 8.1e-13 48.7 0.2 4.2e-12 46.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain WD40 PF00400.32 CDJ81380.1 - 0.00016 22.3 0.0 0.26 12.2 0.0 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ81380.1 - 0.00041 20.6 0.0 0.004 17.4 0.0 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M8 PF01457.16 CDJ81381.1 - 1.7e-47 162.3 0.6 4.5e-47 160.9 0.6 1.6 1 1 0 1 1 1 1 Leishmanolysin Peptidase_M85 PF13678.6 CDJ81381.1 - 0.075 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 NFkB-p65-degrading zinc protease GPW_gp25 PF04965.14 CDJ81381.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Gene 25-like lysozyme TMEM95 PF15203.6 CDJ81381.1 - 0.51 10.0 9.9 34 4.0 10.5 2.5 2 1 0 2 2 2 0 TMEM95 family Motile_Sperm PF00635.26 CDJ81382.1 - 5.5e-13 48.7 0.5 5.5e-13 48.7 0.5 2.9 2 1 0 2 2 2 1 MSP (Major sperm protein) domain zf-CCCH PF00642.24 CDJ81383.1 - 1.7e-21 75.6 17.5 1.1e-10 41.2 6.2 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ81383.1 - 5.8e-11 42.1 19.9 8.6e-06 25.6 5.9 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 CDJ81383.1 - 5e-07 29.4 15.5 1.1e-05 25.1 3.2 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CDJ81383.1 - 0.00015 22.1 9.5 0.047 14.2 0.7 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CDJ81383.1 - 0.26 12.0 10.5 2.2 9.0 1.1 2.3 1 1 1 2 2 2 0 Torus domain oligo_HPY PF08352.12 CDJ81383.1 - 0.83 10.2 7.9 4.4 7.9 1.6 2.6 1 1 1 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region 7TM_GPCR_Srw PF10324.9 CDJ81385.1 - 6.6e-18 65.1 18.9 8.2e-18 64.7 18.9 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 CDJ81385.1 - 2.1e-12 46.9 19.4 2.7e-12 46.6 19.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ninjurin PF04923.12 CDJ81385.1 - 7.6 6.5 10.8 0.24 11.3 3.1 2.4 2 1 0 2 2 2 0 Ninjurin PUB_1 PF18486.1 CDJ81386.1 - 0.00034 20.4 2.3 11 6.0 0.0 4.8 5 0 0 5 5 5 3 PNGase/UBA- or UBX-containing domain Peptidase_M74 PF03411.13 CDJ81386.1 - 0.13 11.7 8.6 7.5 6.0 0.1 4.0 1 1 3 4 4 4 0 Penicillin-insensitive murein endopeptidase Nse4-Nse3_bdg PF15412.6 CDJ81386.1 - 0.41 10.8 8.9 74 3.6 0.1 4.1 4 0 0 4 4 4 0 Binding domain of Nse4/EID3 to Nse3-MAGE GDPD PF03009.17 CDJ81388.1 - 3.5e-12 46.6 0.1 9e-12 45.3 0.1 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family 7TM_GPCR_Srw PF10324.9 CDJ81389.1 - 2.9e-15 56.4 17.5 1e-14 54.6 17.5 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 CDJ81389.1 - 1.6e-14 53.8 15.4 1.6e-14 53.8 15.4 1.7 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) EI24 PF07264.11 CDJ81389.1 - 0.00071 19.9 1.3 0.0012 19.1 1.3 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) CcmD PF04995.14 CDJ81389.1 - 0.0061 16.6 0.8 0.015 15.4 0.8 1.6 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) NumbF PF06311.12 CDJ81389.1 - 0.089 13.4 0.3 0.19 12.3 0.3 1.6 1 0 0 1 1 1 0 NUMB domain DUF5056 PF16479.5 CDJ81389.1 - 0.59 10.4 3.9 0.16 12.2 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) DUF2569 PF10754.9 CDJ81389.1 - 0.95 9.9 10.6 2.2 8.7 10.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) DUF2512 PF10710.9 CDJ81389.1 - 1.4 8.5 9.2 0.2 11.3 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2512) Branch PF02485.21 CDJ81390.1 - 1.9e-25 89.8 0.1 2.4e-25 89.5 0.1 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme zf-CHC2 PF01807.20 CDJ81390.1 - 0.045 13.6 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 CHC2 zinc finger Branch PF02485.21 CDJ81391.1 - 2.2e-39 135.4 0.4 2.8e-39 135.1 0.4 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme SCVP PF17619.2 CDJ81392.1 - 6.9e-18 65.3 0.0 1.3e-17 64.4 0.0 1.5 2 0 0 2 2 2 1 Secreted clade V proteins Pkinase PF00069.25 CDJ81393.1 - 5.5e-70 235.7 0.0 7.2e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ81393.1 - 4e-48 163.9 0.0 5.6e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ81393.1 - 4.2e-05 22.5 0.0 9.1e-05 21.4 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase DUF1241 PF06840.11 CDJ81393.1 - 0.00021 20.9 0.0 0.00043 19.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) APH PF01636.23 CDJ81393.1 - 0.03 14.2 0.0 5.2 6.9 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family G_glu_transpept PF01019.21 CDJ81396.1 - 6e-31 107.8 0.0 7.4e-31 107.5 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase WSK PF03832.13 CDJ81397.1 - 0.098 12.4 0.9 0.36 10.6 0.9 2.0 1 0 0 1 1 1 0 WSK motif ADH_N PF08240.12 CDJ81398.1 - 7.1e-33 112.7 2.8 7.7e-33 112.6 0.7 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDJ81398.1 - 5.6e-23 81.4 0.1 1e-22 80.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CDJ81398.1 - 3.6e-10 39.7 0.6 7.6e-10 38.6 0.6 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 CDJ81398.1 - 0.0016 17.7 0.5 0.0028 17.0 0.5 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Astacin PF01400.24 CDJ81399.1 - 1.9e-53 180.9 0.0 2.1e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 CDJ81399.1 - 0.00079 19.3 0.6 0.0037 17.1 0.6 1.9 1 1 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.6 CDJ81399.1 - 0.00085 19.0 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CDJ81399.1 - 0.0096 16.1 0.0 0.01 16.0 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 CDJ81399.1 - 0.012 14.6 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.6 CDJ81399.1 - 0.027 15.0 0.0 0.048 14.2 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 CDJ81399.1 - 0.079 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Astacin PF01400.24 CDJ81400.1 - 1.4e-59 200.9 0.0 1.8e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 CDJ81400.1 - 0.0029 17.5 1.3 0.014 15.2 0.7 2.0 1 1 1 2 2 2 1 Matrixin Reprolysin_4 PF13583.6 CDJ81400.1 - 0.0061 16.2 0.0 0.0087 15.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 CDJ81400.1 - 0.015 14.3 0.1 0.023 13.7 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.6 CDJ81400.1 - 0.015 15.8 0.0 0.028 14.9 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CDJ81400.1 - 0.069 13.3 0.6 0.13 12.4 0.4 1.4 1 1 0 1 1 1 0 Metallo-peptidase family M12 Metallopep PF12044.8 CDJ81400.1 - 0.083 11.5 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M57 PF12388.8 CDJ81400.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Astacin PF01400.24 CDJ81401.1 - 2.6e-42 144.6 0.0 9.1e-42 142.8 0.0 1.9 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 CDJ81401.1 - 0.0015 18.2 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CDJ81401.1 - 0.0028 17.5 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 CDJ81401.1 - 0.0033 16.4 0.2 0.0056 15.7 0.2 1.4 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M57 PF12388.8 CDJ81401.1 - 0.0053 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase CUB PF00431.20 CDJ81401.1 - 0.0097 16.2 0.4 0.017 15.5 0.4 1.5 1 0 0 1 1 1 1 CUB domain Reprolysin_3 PF13582.6 CDJ81401.1 - 0.089 13.3 1.3 0.25 11.9 0.2 2.2 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF1451 PF07295.11 CDJ81402.1 - 9.5 6.2 8.6 6.6 6.8 3.7 2.8 3 1 0 3 3 3 0 Zinc-ribbon containing domain Acyl-CoA_dh_1 PF00441.24 CDJ81405.1 - 5.9e-49 166.1 0.1 8.7e-49 165.6 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CDJ81405.1 - 8.8e-29 99.6 0.0 1.5e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CDJ81405.1 - 6.6e-28 97.6 0.0 1.5e-27 96.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CDJ81405.1 - 4.4e-22 78.8 0.0 7.6e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 CDJ81405.1 - 0.032 13.9 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_ox_N PF14749.6 CDJ81405.1 - 0.078 13.5 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal HSP20 PF00011.21 CDJ81406.1 - 1.5e-21 76.4 0.1 2.2e-21 75.9 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ81406.1 - 0.0002 20.9 0.0 0.00032 20.2 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Cupredoxin_1 PF13473.6 CDJ81406.1 - 0.045 13.9 0.3 0.058 13.5 0.3 1.3 1 1 0 1 1 1 0 Cupredoxin-like domain Acyl-CoA_dh_1 PF00441.24 CDJ81407.1 - 1.2e-48 165.2 0.2 1.6e-48 164.7 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CDJ81407.1 - 4.7e-31 107.8 0.0 1.4e-29 103.0 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CDJ81407.1 - 6.9e-27 93.5 0.0 1.2e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CDJ81407.1 - 2.1e-22 79.8 0.0 2.9e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 CDJ81407.1 - 0.0015 19.0 0.0 0.0032 18.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal YycC PF14174.6 CDJ81408.1 - 0.084 12.7 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 YycC-like protein RT_RNaseH_2 PF17919.1 CDJ81409.1 - 2.7e-33 114.0 0.0 4.9e-33 113.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ81409.1 - 3.6e-28 97.9 0.0 8.2e-28 96.8 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ81409.1 - 4.8e-16 58.6 0.0 9.6e-16 57.6 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 CDJ81409.1 - 1.3e-07 31.4 0.0 3.3e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 CDJ81409.1 - 5.3e-05 23.3 0.0 0.00012 22.2 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Patched PF02460.18 CDJ81410.1 - 7.7e-40 136.8 19.3 9.9e-40 136.4 19.3 1.1 1 0 0 1 1 1 1 Patched family TUDOR PF00567.24 CDJ81411.1 - 0.0067 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Tudor domain DnaJ PF00226.31 CDJ81412.1 - 9.5e-06 25.7 0.0 2.2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain eIF-1a PF01176.19 CDJ81413.1 - 3.9e-32 109.9 12.1 6.3e-19 67.5 0.9 3.7 4 0 0 4 4 4 3 Translation initiation factor 1A / IF-1 Rhabdo_M2 PF04785.12 CDJ81413.1 - 0.01 15.2 0.5 2.1 7.6 0.0 3.0 4 0 0 4 4 4 0 Rhabdovirus matrix protein M2 CSD2 PF17876.1 CDJ81413.1 - 0.024 14.8 0.1 16 5.7 0.0 3.4 3 0 0 3 3 3 0 Cold shock domain CDC48_N PF02359.18 CDJ81413.1 - 0.032 14.4 0.6 0.079 13.1 0.2 1.9 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain Laterosporulin PF17861.1 CDJ81413.1 - 0.16 12.4 1.8 16 6.0 0.1 3.3 4 0 0 4 4 4 0 Laterosporulin defensin-like peptide RsgA_N PF16745.5 CDJ81413.1 - 0.39 10.5 6.2 0.097 12.4 1.3 2.3 2 0 0 2 2 2 0 RsgA N-terminal domain Exo_endo_phos_2 PF14529.6 CDJ81414.1 - 2.7e-06 27.2 0.0 5.5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ81414.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.6 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Ribosomal_S5 PF00333.20 CDJ81414.1 - 0.12 12.4 0.1 0.37 10.8 0.1 1.8 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain DivIC PF04977.15 CDJ81414.1 - 0.13 12.0 0.0 2.7 7.8 0.0 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF5615 PF18480.1 CDJ81414.1 - 0.16 11.8 0.0 5.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) MATH PF00917.26 CDJ81415.1 - 1.1e-13 51.3 0.6 1.1e-13 51.3 0.6 2.3 3 0 0 3 3 3 1 MATH domain SUIM_assoc PF16619.5 CDJ81415.1 - 0.0061 16.6 6.1 0.0061 16.6 6.1 5.6 6 0 0 6 6 6 1 Unstructured region C-term to UIM in Ataxin3 TPR_1 PF00515.28 CDJ81415.1 - 0.012 15.4 0.2 0.039 13.8 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Transmemb_17 PF09799.9 CDJ81416.1 - 9.8e-22 77.6 14.0 1.2e-21 77.3 14.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein RhoGAP PF00620.27 CDJ81417.1 - 6.1e-23 81.3 0.0 1.1e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Rotamase PF00639.21 CDJ81418.1 - 6.4e-22 78.3 0.0 8.3e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CDJ81418.1 - 4.4e-20 72.4 0.0 5.8e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 CDJ81418.1 - 4.4e-12 45.9 0.9 7.3e-12 45.2 0.9 1.4 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 CDJ81418.1 - 0.00057 20.7 0.0 0.0012 19.7 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain EntA_Immun PF08951.10 CDJ81418.1 - 0.0067 16.8 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 Enterocin A Immunity X8 PF07983.13 CDJ81418.1 - 0.013 16.2 0.7 0.017 15.8 0.0 1.6 2 0 0 2 2 2 0 X8 domain MBD PF01429.19 CDJ81418.1 - 0.053 13.2 0.3 0.3 10.8 0.1 2.1 2 0 0 2 2 2 0 Methyl-CpG binding domain MDD_C PF18376.1 CDJ81419.1 - 1.1e-60 204.5 0.0 1.6e-60 204.1 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 CDJ81419.1 - 6e-07 29.6 3.9 1.6e-06 28.2 3.9 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain Malic_M PF03949.15 CDJ81420.1 - 3e-99 331.5 0.1 3.8e-99 331.1 0.1 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CDJ81420.1 - 1e-72 243.7 0.0 1.6e-72 243.1 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 CDJ81421.1 - 7e-99 330.3 0.2 8.9e-99 329.9 0.2 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CDJ81421.1 - 4.1e-75 251.6 0.0 6.3e-75 251.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain GoLoco PF02188.17 CDJ81422.1 - 7.7e-31 105.1 26.5 1.6e-08 33.9 5.7 4.7 4 0 0 4 4 4 4 GoLoco motif TPR_12 PF13424.6 CDJ81422.1 - 7.9e-20 70.9 20.2 5.6e-10 39.4 0.2 5.6 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ81422.1 - 4.3e-15 54.8 16.4 3.8e-05 23.3 0.3 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ81422.1 - 6e-14 51.0 11.3 0.01 15.8 0.1 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat Xpo1 PF08389.12 CDJ81422.1 - 3.5e-08 33.6 0.5 1.5e-07 31.5 0.1 2.3 3 0 0 3 3 3 1 Exportin 1-like protein TPR_2 PF07719.17 CDJ81422.1 - 1.8e-06 27.6 16.8 0.054 13.6 0.2 7.7 7 0 0 7 7 7 2 Tetratricopeptide repeat SNAP PF14938.6 CDJ81422.1 - 0.0047 16.4 2.4 0.0047 16.4 2.4 2.7 2 1 1 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_8 PF13181.6 CDJ81422.1 - 0.0081 16.3 25.1 0.064 13.5 0.2 7.9 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ81422.1 - 0.038 13.9 16.2 5.6 7.0 0.6 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ81422.1 - 0.04 13.6 11.8 4.3 7.1 0.3 5.2 5 1 0 5 5 5 0 TPR repeat TPR_MalT PF17874.1 CDJ81422.1 - 0.041 13.2 7.5 0.36 10.2 0.3 3.4 3 1 0 3 3 3 0 MalT-like TPR region TPR_16 PF13432.6 CDJ81422.1 - 0.1 13.3 6.5 40 5.0 0.0 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat HTH_48 PF17906.1 CDJ81423.1 - 4.7e-18 65.0 0.4 8.5e-18 64.2 0.4 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_Tnp_Tc3_2 PF01498.18 CDJ81423.1 - 2.4e-07 30.9 0.7 5.1e-07 29.8 0.7 1.6 1 0 0 1 1 1 1 Transposase HTH_Tnp_IS630 PF01710.16 CDJ81423.1 - 4.5e-06 26.7 0.0 6.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 CDJ81423.1 - 6.8e-05 23.4 2.1 7.9e-05 23.2 0.1 2.2 2 1 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.6 CDJ81423.1 - 0.00014 21.5 0.1 0.00043 20.0 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_50 PF18024.1 CDJ81423.1 - 0.00032 20.2 0.2 0.0008 19.0 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 CDJ81423.1 - 0.001 18.8 0.1 0.17 11.7 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_11 PF08279.12 CDJ81423.1 - 0.0052 16.7 0.1 0.012 15.5 0.1 1.6 1 0 0 1 1 1 1 HTH domain HTH_28 PF13518.6 CDJ81423.1 - 0.0079 16.3 0.1 2.1 8.5 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_40 PF14493.6 CDJ81423.1 - 0.016 15.7 0.1 0.033 14.6 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_36 PF13730.6 CDJ81423.1 - 0.017 15.1 0.0 0.63 10.0 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_6 PF01418.17 CDJ81423.1 - 0.069 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family TubC_N PF18563.1 CDJ81423.1 - 0.089 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 TubC N-terminal docking domain IF2_N PF04760.15 CDJ81423.1 - 0.12 12.3 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region HTH_5 PF01022.20 CDJ81423.1 - 0.13 12.1 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family KASH_CCD PF14662.6 CDJ81425.1 - 0.0021 17.9 0.6 0.0025 17.7 0.6 1.0 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Syntaxin-6_N PF09177.11 CDJ81425.1 - 0.0056 17.2 2.0 0.015 15.9 1.9 1.6 1 1 0 1 1 1 1 Syntaxin 6, N-terminal GAS PF13851.6 CDJ81425.1 - 0.015 14.7 1.3 0.018 14.4 1.3 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding HMMR_N PF15905.5 CDJ81425.1 - 0.018 14.5 2.9 0.02 14.4 2.9 1.0 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF4472 PF14739.6 CDJ81425.1 - 0.022 15.5 1.3 0.028 15.1 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) BST2 PF16716.5 CDJ81425.1 - 0.026 15.1 2.5 0.031 14.9 2.5 1.1 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 ATG16 PF08614.11 CDJ81425.1 - 0.047 13.9 5.6 0.054 13.7 5.6 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF724 PF05266.14 CDJ81425.1 - 0.05 13.4 2.2 0.061 13.1 2.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ING PF12998.7 CDJ81425.1 - 0.059 14.0 0.6 0.07 13.7 0.6 1.1 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding UPF0270 PF06794.12 CDJ81425.1 - 0.096 12.8 1.1 0.32 11.1 0.1 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0270) RVT_1 PF00078.27 CDJ81426.1 - 1.6e-11 44.2 0.0 2.1e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CDJ81427.1 - 4.2e-09 36.3 0.0 6.1e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ArgoN PF16486.5 CDJ81428.1 - 5.4e-07 30.3 0.0 1.4e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute IKI3 PF04762.12 CDJ81429.1 - 6.9e-143 477.8 6.4 2.2e-141 472.8 6.4 2.0 1 1 0 1 1 1 1 IKI3 family Pkinase PF00069.25 CDJ81429.1 - 3.3e-47 161.1 0.0 7.1e-47 160.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ81429.1 - 5.6e-33 114.3 0.0 1.1e-32 113.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Clathrin PF00637.20 CDJ81429.1 - 0.0024 17.7 2.1 0.32 10.8 0.1 3.5 1 1 2 3 3 3 1 Region in Clathrin and VPS PB1 PF00564.24 CDJ81429.1 - 0.0084 16.0 0.0 0.025 14.5 0.0 1.7 1 0 0 1 1 1 1 PB1 domain Intein_splicing PF14890.6 CDJ81429.1 - 0.018 15.0 0.1 0.046 13.7 0.1 1.7 1 0 0 1 1 1 0 Intein splicing domain TMEM220 PF15071.6 CDJ81431.1 - 0.0015 19.2 2.6 0.0016 19.2 1.3 1.7 1 1 1 2 2 2 1 Transmembrane family 220, helix WD40 PF00400.32 CDJ81432.1 - 2.6e-22 78.7 8.5 8.7e-06 26.4 0.0 6.0 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ81432.1 - 4e-14 52.7 0.0 0.00071 19.8 0.0 4.2 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ81432.1 - 0.0013 17.7 0.2 3.8 6.4 0.0 3.2 3 0 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CDJ81432.1 - 0.036 12.7 0.2 0.047 12.3 0.2 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Aa_trans PF01490.18 CDJ81433.1 - 1.1e-06 27.7 0.3 1.3e-06 27.4 0.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein GrpE PF01025.19 CDJ81433.1 - 0.0035 17.0 0.2 0.0061 16.2 0.1 1.4 1 1 0 1 1 1 1 GrpE EGF_2 PF07974.13 CDJ81434.1 - 3.7 8.0 47.9 0.035 14.5 1.8 5.0 5 0 0 5 5 5 0 EGF-like domain AA_kinase PF00696.28 CDJ81435.1 - 6.5e-20 71.8 0.1 8.8e-20 71.3 0.1 1.1 1 0 0 1 1 1 1 Amino acid kinase family IL17 PF06083.11 CDJ81436.1 - 3.9e-05 24.0 0.7 5.2e-05 23.6 0.7 1.2 1 0 0 1 1 1 1 Interleukin-17 I-set PF07679.16 CDJ81437.1 - 0 1566.9 0.0 1.1e-21 76.7 0.0 33.4 33 0 0 33 33 33 33 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ81437.1 - 0 1004.5 0.0 1.2e-11 45.0 0.0 33.6 33 0 0 33 33 33 33 Immunoglobulin domain Ig_2 PF13895.6 CDJ81437.1 - 3.4e-178 578.4 0.0 4.2e-09 36.6 0.0 33.3 33 0 0 33 33 33 28 Immunoglobulin domain ig PF00047.25 CDJ81437.1 - 4.4e-153 497.9 0.0 5.9e-07 29.6 0.0 32.3 32 0 0 32 32 32 24 Immunoglobulin domain V-set PF07686.17 CDJ81437.1 - 2.4e-86 285.1 1.0 0.018 15.2 0.0 39.0 33 9 0 33 33 33 15 Immunoglobulin V-set domain Titin_Ig-rpts PF06582.12 CDJ81437.1 - 5.7e-56 186.1 61.8 0.00016 21.6 0.4 17.7 18 0 0 18 18 18 14 Titin repeat C1-set PF07654.15 CDJ81437.1 - 9.1e-42 141.3 0.1 0.023 15.1 0.0 24.8 29 0 0 29 29 27 5 Immunoglobulin C1-set domain BiPBP_C PF06832.12 CDJ81437.1 - 3.9e-37 126.2 3.0 2.2 8.4 0.0 27.0 29 3 0 29 29 28 1 Penicillin-Binding Protein C-terminus Family C2-set_2 PF08205.12 CDJ81437.1 - 1.4e-27 95.5 9.9 0.57 10.3 0.0 20.4 24 0 0 24 24 23 4 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 CDJ81437.1 - 2.2e-23 81.6 2.1 0.54 9.9 0.0 16.8 20 0 0 20 20 18 4 Immunoglobulin domain V-set_CD47 PF08204.11 CDJ81437.1 - 1e-20 74.0 0.5 0.99 9.4 0.0 16.4 16 1 1 17 17 16 2 CD47 immunoglobulin-like domain Receptor_2B4 PF11465.8 CDJ81437.1 - 1.3e-16 60.7 0.0 8.1 6.7 0.0 16.6 20 1 1 21 21 18 1 Natural killer cell receptor 2B4 Ig_4 PF16680.5 CDJ81437.1 - 7.8e-15 54.9 0.2 2.6 8.4 0.0 14.4 17 0 0 17 17 15 2 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 CDJ81437.1 - 1.6e-06 28.0 10.7 11 6.1 0.0 12.4 18 0 0 18 18 15 0 C17orf99 Ig domain C2-set PF05790.15 CDJ81437.1 - 0.00026 21.1 11.6 22 5.3 0.1 8.8 10 0 0 10 10 8 0 Immunoglobulin C2-set domain DUF11 PF01345.18 CDJ81437.1 - 0.00036 20.8 4.9 76 3.7 0.0 8.8 9 0 0 9 9 9 0 Domain of unknown function DUF11 bMG6 PF17962.1 CDJ81437.1 - 0.0068 16.5 4.6 40 4.4 0.0 8.3 11 0 0 11 11 9 0 Bacterial macroglobulin domain 6 LicD PF04991.13 CDJ81437.1 - 0.068 13.3 1.1 10 6.2 0.3 2.5 2 0 0 2 2 2 0 LicD family Big_1 PF02369.16 CDJ81437.1 - 1 9.4 3.8 14 5.8 0.0 5.2 5 0 0 5 5 2 0 Bacterial Ig-like domain (group 1) MMPL PF03176.15 CDJ81438.1 - 0.00044 19.3 4.6 0.012 14.5 0.0 2.1 1 1 0 2 2 2 2 MMPL family Apolipoprotein PF01442.18 CDJ81438.1 - 0.2 11.5 30.0 0.086 12.7 5.5 2.6 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain LMBR1 PF04791.16 CDJ81438.1 - 0.3 9.9 21.9 9 5.1 21.9 2.0 1 1 0 1 1 1 0 LMBR1-like membrane protein OmpH PF03938.14 CDJ81438.1 - 0.45 10.9 40.5 0.44 10.9 0.4 3.1 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Pex19 PF04614.12 CDJ81438.1 - 0.58 9.9 23.1 2.2 8.0 11.0 2.4 1 1 1 2 2 2 0 Pex19 protein family DUF5082 PF16888.5 CDJ81438.1 - 1.1 9.6 26.3 1.5 9.1 4.8 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) DUF4381 PF14316.6 CDJ81438.1 - 1.1 9.4 0.0 1.1 9.4 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4381) Baculo_PEP_C PF04513.12 CDJ81438.1 - 1.2 9.2 7.5 2.3 8.3 0.6 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_M75 PF09375.10 CDJ81438.1 - 1.5 8.2 16.1 0.2 11.1 2.7 2.8 1 1 0 2 2 2 0 Imelysin PAS_10 PF13596.6 CDJ81438.1 - 2.5 8.7 5.4 0.92 10.1 0.3 2.6 3 0 0 3 3 3 0 PAS domain ERCC4 PF02732.15 CDJ81438.1 - 3.1 8.0 10.2 0.36 11.0 5.9 1.6 2 0 0 2 2 2 0 ERCC4 domain ST7 PF04184.12 CDJ81438.1 - 7 5.0 8.7 12 4.3 8.7 1.3 1 0 0 1 1 1 0 ST7 protein DUF883 PF05957.13 CDJ81438.1 - 7.6 7.2 23.1 0.77 10.4 4.6 3.5 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Collagen PF01391.18 CDJ81439.1 - 4.8e-24 83.9 114.3 2.7e-09 36.7 31.8 3.6 2 1 2 4 4 4 3 Collagen triple helix repeat (20 copies) zf-H2C2_5 PF13909.6 CDJ81440.1 - 5e-09 35.7 5.5 3.6e-07 29.8 0.7 4.7 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 CDJ81440.1 - 5.2e-05 23.5 2.5 5.2e-05 23.5 2.5 5.8 6 0 0 6 6 6 1 Zinc-finger double domain zf-C2H2 PF00096.26 CDJ81440.1 - 0.049 14.1 24.3 0.39 11.3 1.0 5.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type Pkinase PF00069.25 CDJ81441.1 - 3.2e-53 180.8 0.0 4.4e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ81441.1 - 9.2e-33 113.6 0.0 1.3e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ81441.1 - 5.6e-05 22.1 0.0 7.7e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CDJ81441.1 - 0.0026 16.8 0.3 0.0044 16.0 0.3 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 CDJ81441.1 - 0.01 14.9 0.3 0.015 14.3 0.3 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 CDJ81441.1 - 0.019 14.3 0.0 0.12 11.7 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Choline_kinase PF01633.20 CDJ81441.1 - 0.11 12.1 0.0 0.39 10.3 0.0 1.9 1 1 0 1 1 1 0 Choline/ethanolamine kinase TACC_C PF05010.14 CDJ81442.1 - 1e-12 48.3 10.3 1e-12 48.3 10.3 2.4 2 1 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF4407 PF14362.6 CDJ81442.1 - 0.17 11.2 7.4 0.98 8.7 6.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Prominin PF05478.11 CDJ81442.1 - 0.21 9.5 8.7 0.18 9.7 5.7 1.9 1 1 1 2 2 2 0 Prominin GrpE PF01025.19 CDJ81442.1 - 0.25 11.0 17.1 0.35 10.5 7.7 3.2 2 1 1 3 3 3 0 GrpE DUF883 PF05957.13 CDJ81442.1 - 0.49 11.0 9.8 0.47 11.1 1.7 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Anthrax_toxA PF03497.16 CDJ81442.1 - 0.87 9.7 4.9 0.75 9.9 1.2 2.3 2 0 0 2 2 2 0 Anthrax toxin LF subunit Phage_GPO PF05929.11 CDJ81442.1 - 1.1 8.8 5.9 0.44 10.1 0.3 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Laminin_II PF06009.12 CDJ81442.1 - 1.4 8.9 10.2 8.8 6.3 0.3 3.5 2 1 1 3 3 3 0 Laminin Domain II Golgin_A5 PF09787.9 CDJ81442.1 - 2 7.8 24.1 1.5 8.2 11.3 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 MbeD_MobD PF04899.12 CDJ81442.1 - 2.3 8.4 7.4 0.52 10.5 0.3 3.2 3 1 0 3 3 3 0 MbeD/MobD like PRCC PF10253.9 CDJ81442.1 - 6.5 7.5 12.3 10 6.9 6.0 2.1 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting CAP PF00188.26 CDJ81443.1 - 2e-17 64.2 5.7 2.9e-17 63.7 5.7 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ExsD PF16806.5 CDJ81444.1 - 0.042 13.8 0.2 0.062 13.2 0.2 1.2 1 0 0 1 1 1 0 Antiactivator protein ExsD AAA_24 PF13479.6 CDJ81444.1 - 0.047 13.4 0.1 0.058 13.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain Ndufs5 PF10200.9 CDJ81445.1 - 4.5e-12 46.1 0.7 5.9e-12 45.7 0.7 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cmc1 PF08583.10 CDJ81445.1 - 0.066 13.2 1.6 0.08 13.0 1.6 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 CDJ81445.1 - 0.12 12.5 3.6 0.19 11.9 3.6 1.3 1 0 0 1 1 1 0 CHCH domain COX6B PF02297.17 CDJ81445.1 - 0.44 10.8 4.2 1 9.6 4.2 1.6 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb Det1 PF09737.9 CDJ81446.1 - 1.3e-52 179.3 0.0 1.7e-52 178.9 0.0 1.1 1 0 0 1 1 1 1 De-etiolated protein 1 Det1 Ras PF00071.22 CDJ81447.1 - 1.3e-24 86.6 0.0 1.6e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ81447.1 - 5.3e-05 23.4 0.1 0.0001 22.5 0.1 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 CDJ81447.1 - 0.0045 17.1 0.2 0.0082 16.3 0.2 1.4 1 0 0 1 1 1 1 Helicase HerA, central domain NB-ARC PF00931.22 CDJ81447.1 - 0.05 12.8 0.2 0.087 12.0 0.1 1.4 1 1 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 CDJ81447.1 - 0.098 13.0 0.1 0.22 11.9 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain GlutR_dimer PF00745.20 CDJ81448.1 - 0.076 13.5 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain Tetraspanin PF00335.20 CDJ81449.1 - 9.9e-11 41.8 2.2 1.5e-10 41.2 2.2 1.3 1 0 0 1 1 1 1 Tetraspanin family DUF627 PF04781.12 CDJ81449.1 - 0.038 14.0 0.3 0.13 12.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF627) Abhydrolase_9_N PF15420.6 CDJ81449.1 - 0.27 11.2 5.1 0.3 11.0 1.9 2.0 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus GCV_H PF01597.19 CDJ81450.1 - 1.5e-46 157.3 0.4 1.8e-46 157.0 0.4 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 CDJ81450.1 - 0.026 14.5 0.1 0.05 13.6 0.1 1.4 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain RNaseH_C PF09293.10 CDJ81450.1 - 0.064 13.6 0.4 0.68 10.3 0.4 2.1 1 1 0 1 1 1 0 T4 RNase H, C terminal XPA_C PF05181.12 CDJ81451.1 - 1.4e-23 82.6 0.7 3e-23 81.5 0.7 1.6 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 CDJ81451.1 - 7.5e-12 45.1 3.2 7.5e-12 45.1 3.2 2.1 2 0 0 2 2 2 1 XPA protein N-terminal MBOAT PF03062.19 CDJ81452.1 - 2.4e-15 56.8 10.3 2.6e-15 56.6 10.3 1.0 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 CDJ81452.1 - 0.28 11.5 5.9 0.44 10.9 5.9 1.4 1 1 0 1 1 1 0 Membrane bound O-acyl transferase family ZT_dimer PF16916.5 CDJ81453.1 - 2.1e-09 37.4 0.3 3.1e-09 36.8 0.3 1.2 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Cation_efflux PF01545.21 CDJ81453.1 - 9.5e-07 28.7 0.4 1.3e-06 28.2 0.4 1.2 1 0 0 1 1 1 1 Cation efflux family TPR_1 PF00515.28 CDJ81456.1 - 2.1e-25 87.4 5.7 4.6e-06 26.2 0.1 5.4 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ81456.1 - 5.8e-24 82.2 8.8 3.2e-05 23.7 0.0 5.8 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ81456.1 - 1e-18 65.9 0.7 0.00027 20.9 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ81456.1 - 1.9e-18 65.9 6.2 3.6e-07 29.8 0.0 6.1 4 2 2 6 6 6 3 TPR repeat TPR_16 PF13432.6 CDJ81456.1 - 5e-16 59.1 13.6 2.1e-06 28.3 0.1 5.0 2 2 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ81456.1 - 2.1e-15 56.1 9.4 0.00029 21.4 0.2 6.6 4 2 3 7 7 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ81456.1 - 8.7e-13 47.7 14.9 0.00059 20.0 0.2 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ81456.1 - 2.7e-11 43.8 9.8 0.011 16.2 0.0 4.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ81456.1 - 7.8e-11 41.9 0.7 1.2 9.9 0.1 6.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ81456.1 - 3.9e-09 36.7 7.9 0.00017 21.8 0.6 4.1 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ81456.1 - 7e-06 26.1 6.9 0.0054 16.9 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 CDJ81456.1 - 8.5e-06 26.0 12.3 0.32 11.4 0.7 5.3 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ81456.1 - 9.6e-05 22.2 9.6 0.018 15.1 0.1 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ81456.1 - 0.0026 17.6 14.2 0.7 9.8 1.2 4.7 5 0 0 5 5 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ81456.1 - 0.0034 17.6 7.8 0.25 11.6 0.1 3.3 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 KfrA_N PF11740.8 CDJ81456.1 - 1.7 9.4 8.4 2.5 8.8 3.3 2.9 3 0 0 3 3 2 0 Plasmid replication region DNA-binding N-term TM231 PF10149.9 CDJ81457.1 - 5.7e-15 55.4 0.6 6.4e-15 55.3 0.6 1.0 1 0 0 1 1 1 1 Transmembrane protein 231 GPS PF01825.21 CDJ81460.1 - 4e-06 27.2 0.8 1.7e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif Cadherin_pro PF08758.11 CDJ81460.1 - 0.00063 19.8 0.0 0.0018 18.4 0.0 1.7 1 0 0 1 1 1 1 Cadherin prodomain like fn3 PF00041.21 CDJ81460.1 - 0.0013 19.1 0.0 0.0027 18.0 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain HRM PF02793.22 CDJ81460.1 - 0.0024 18.1 2.8 0.0067 16.7 2.8 1.8 1 0 0 1 1 1 1 Hormone receptor domain Cadherin PF00028.17 CDJ81460.1 - 0.04 14.3 0.0 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 Cadherin domain Ion_trans PF00520.31 CDJ81462.1 - 5.3e-31 107.7 3.0 7.8e-31 107.2 3.0 1.2 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.11 CDJ81462.1 - 9e-29 99.5 2.4 2.5e-28 98.1 2.4 1.8 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.7 CDJ81462.1 - 5.2e-10 39.8 0.8 3.4e-06 27.6 0.3 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ81462.1 - 7.6e-10 39.1 0.1 0.00012 22.5 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PKD_channel PF08016.12 CDJ81462.1 - 1e-07 31.0 5.8 6e-06 25.2 0.5 2.2 2 0 0 2 2 2 2 Polycystin cation channel Ank_5 PF13857.6 CDJ81462.1 - 0.00031 21.0 0.1 0.26 11.7 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ81462.1 - 0.00093 19.5 7.3 0.034 14.7 0.1 4.3 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 CDJ81462.1 - 0.0014 19.0 0.2 1.2 9.8 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat DUF1490 PF07371.12 CDJ81463.1 - 0.029 14.4 0.2 0.047 13.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1490) Retrotrans_gag PF03732.17 CDJ81463.1 - 0.054 13.8 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein Molybdop_Fe4S4 PF04879.16 CDJ81464.1 - 0.14 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Fe4S4 domain Aminotran_3 PF00202.21 CDJ81469.1 - 3.1e-47 161.1 0.0 3.7e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III T4SS_CagC PF16943.5 CDJ81470.1 - 0.1 12.8 1.4 0.14 12.4 1.4 1.2 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system Orf78 PF06024.12 CDJ81470.1 - 0.25 11.6 1.1 0.43 10.9 1.1 1.4 1 0 0 1 1 1 0 Orf78 (ac78) A_deaminase PF00962.22 CDJ81472.1 - 8.1e-29 101.0 0.0 1e-28 100.6 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 CDJ81472.1 - 0.0011 18.4 0.0 0.0035 16.7 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family HDC PF02329.16 CDJ81472.1 - 0.071 12.1 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Histidine carboxylase PI chain DUF1476 PF07345.11 CDJ81472.1 - 0.16 12.3 0.3 0.33 11.3 0.3 1.5 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF3196 PF11428.8 CDJ81473.1 - 0.016 14.7 0.1 0.027 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3196) HBS1_N PF08938.10 CDJ81473.1 - 0.056 13.7 0.5 2.6 8.4 0.0 2.6 2 0 0 2 2 2 0 HBS1 N-terminus MARVEL PF01284.23 CDJ81474.1 - 0.0023 18.0 9.9 0.0037 17.3 9.8 1.4 1 1 0 1 1 1 1 Membrane-associating domain BetR PF08667.10 CDJ81474.1 - 0.033 14.2 0.0 3.4 7.7 0.0 2.1 2 0 0 2 2 2 0 BetR domain DHHC PF01529.20 CDJ81474.1 - 1.2 9.2 4.4 1.9 8.6 4.1 1.5 1 1 0 1 1 1 0 DHHC palmitoyltransferase DUF2244 PF10003.9 CDJ81474.1 - 2.3 7.9 4.6 9.5 5.9 1.0 2.2 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Zona_pellucida PF00100.23 CDJ81475.1 - 2.2e-12 47.3 5.8 3.9e-12 46.5 5.8 1.4 1 0 0 1 1 1 1 Zona pellucida-like domain Patched PF02460.18 CDJ81478.1 - 1e-140 470.4 2.2 1.3e-140 470.1 2.2 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 CDJ81478.1 - 1.7e-15 57.2 0.1 1.7e-15 57.2 0.1 2.8 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 CDJ81478.1 - 0.024 13.5 0.0 0.024 13.5 0.0 2.8 3 0 0 3 3 3 0 MMPL family SecD_SecF PF02355.16 CDJ81478.1 - 0.038 13.4 18.9 0.028 13.8 15.7 2.3 2 1 0 2 2 2 0 Protein export membrane protein ACR_tran PF00873.19 CDJ81478.1 - 1.8 6.1 13.1 0.032 11.9 6.3 1.4 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family HTH_32 PF13565.6 CDJ81479.1 - 0.14 12.8 4.8 13 6.5 0.1 3.5 3 0 0 3 3 3 0 Homeodomain-like domain MFS_1 PF07690.16 CDJ81480.1 - 2.7e-25 89.0 24.2 2.7e-25 89.0 24.2 2.0 2 1 1 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ81480.1 - 3.1e-25 89.0 19.7 4.2e-25 88.5 19.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Peptidase_U4 PF03419.13 CDJ81480.1 - 0.0065 15.8 8.7 0.0065 15.8 8.7 2.2 2 0 0 2 2 2 1 Sporulation factor SpoIIGA Lectin_C PF00059.21 CDJ81481.1 - 2.3e-11 44.4 0.3 3e-11 44.0 0.3 1.2 1 0 0 1 1 1 1 Lectin C-type domain DUF3048_C PF17479.2 CDJ81481.1 - 0.0074 16.7 0.1 0.45 10.9 0.1 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3048) C-terminal domain Lir1 PF07207.11 CDJ81481.1 - 0.11 12.8 0.1 0.18 12.1 0.1 1.3 1 0 0 1 1 1 0 Light regulated protein Lir1 Asp PF00026.23 CDJ81482.1 - 1.9e-27 96.5 0.0 2.4e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ81482.1 - 5.4e-10 39.8 3.8 3e-09 37.4 3.8 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal UL42 PF17638.2 CDJ81483.1 - 0.76 9.8 7.3 2.5 8.1 1.7 2.4 2 0 0 2 2 2 0 HCMV UL42 Myotub-related PF06602.14 CDJ81484.1 - 2.8e-108 362.0 0.2 4.3e-108 361.4 0.2 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FYVE PF01363.21 CDJ81484.1 - 1.1e-08 35.1 9.1 1.1e-08 35.1 9.1 2.4 2 0 0 2 2 2 1 FYVE zinc finger Y_phosphatase3 PF13350.6 CDJ81484.1 - 0.0099 15.9 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CDJ81484.1 - 0.14 11.7 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ81484.1 - 0.16 11.8 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF4083 PF13314.6 CDJ81486.1 - 0.2 11.6 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) ABC_tran_2 PF16949.5 CDJ81487.1 - 0.034 13.0 0.1 0.041 12.7 0.1 1.0 1 0 0 1 1 1 0 Putative ATP-binding cassette DUF4179 PF13786.6 CDJ81487.1 - 0.093 13.2 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) VirB8 PF04335.13 CDJ81487.1 - 0.11 12.4 0.1 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 VirB8 protein DUF872 PF05915.12 CDJ81487.1 - 0.12 12.5 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Pkinase PF00069.25 CDJ81488.1 - 8.9e-57 192.4 0.0 9.1e-57 192.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ81488.1 - 1.5e-31 109.6 0.0 1.9e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ81488.1 - 0.00091 19.2 0.6 0.0018 18.2 0.4 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ81488.1 - 0.0016 17.8 1.1 0.0041 16.5 1.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDJ81488.1 - 0.0022 17.3 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CDJ81488.1 - 0.0033 16.4 0.1 0.0044 16.0 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CDJ81488.1 - 0.015 14.9 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 CDJ81488.1 - 0.022 13.8 0.1 0.032 13.3 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 CDJ81488.1 - 0.18 11.4 0.4 0.34 10.5 0.3 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Med13_C PF06333.12 CDJ81489.1 - 6.2e-85 285.4 0.1 6.2e-85 285.4 0.1 3.1 4 0 0 4 4 4 1 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 CDJ81489.1 - 3.7e-25 89.1 0.9 1.3e-24 87.3 0.0 2.4 2 0 0 2 2 2 1 MID domain of medPIWI Med13_N PF11597.8 CDJ81489.1 - 5.4e-23 81.9 0.0 1.4e-22 80.5 0.0 1.7 1 1 0 1 1 1 1 Mediator complex subunit 13 N-terminal Pheromone PF08015.11 CDJ81489.1 - 0.49 11.5 5.4 0.78 10.8 0.1 4.3 3 0 0 3 3 3 0 Fungal mating-type pheromone Dynamin_M PF01031.20 CDJ81490.1 - 1.6e-105 352.4 2.1 1.6e-105 352.4 2.1 2.3 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 CDJ81490.1 - 1.3e-54 184.8 0.1 3.7e-54 183.3 0.0 1.9 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 CDJ81490.1 - 6.2e-27 93.6 4.6 2.1e-26 91.9 4.6 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain PH PF00169.29 CDJ81490.1 - 1.5e-09 38.3 0.4 3.7e-09 37.0 0.4 1.7 1 0 0 1 1 1 1 PH domain MMR_HSR1 PF01926.23 CDJ81490.1 - 0.00014 21.9 0.0 0.00049 20.2 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase ALO PF04030.14 CDJ81490.1 - 0.015 15.1 0.2 0.32 10.8 0.1 2.5 2 0 0 2 2 2 0 D-arabinono-1,4-lactone oxidase RasGAP PF00616.19 CDJ81490.1 - 0.042 13.5 1.0 0.065 12.9 0.2 1.7 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase Sulfatase_C PF14707.6 CDJ81490.1 - 0.1 13.3 0.0 9.2 7.0 0.0 3.1 3 0 0 3 3 3 0 C-terminal region of aryl-sulfatase TetR_C_24 PF17932.1 CDJ81490.1 - 0.19 12.0 0.3 3.4 8.0 0.0 2.7 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain RVT_1 PF00078.27 CDJ81491.1 - 4.8e-16 59.0 0.1 6.5e-16 58.5 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Collagen PF01391.18 CDJ81493.1 - 9.5e-27 92.5 74.6 1.1e-09 37.9 24.7 4.1 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ81493.1 - 2e-12 46.9 0.1 3e-12 46.4 0.1 1.3 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain RRM_1 PF00076.22 CDJ81495.1 - 4.3e-10 39.3 0.2 6.9e-10 38.6 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) dsDNA_bind PF01984.20 CDJ81495.1 - 0.11 12.8 0.1 0.15 12.4 0.1 1.2 1 0 0 1 1 1 0 Double-stranded DNA-binding domain 7tm_1 PF00001.21 CDJ81496.1 - 8e-21 74.5 10.6 1.1e-20 74.1 10.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDJ81496.1 - 4.7e-15 55.7 14.2 6.2e-15 55.3 14.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 CDJ81496.1 - 5.3e-11 42.4 11.8 3.4e-10 39.7 11.8 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 CDJ81496.1 - 2.3e-06 27.4 13.3 3.9e-06 26.7 13.3 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Pkinase PF00069.25 CDJ81498.1 - 6.7e-46 156.8 0.0 8.3e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ81498.1 - 5.5e-24 84.9 0.0 6.9e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ81498.1 - 2.3e-06 27.1 0.0 3.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ81498.1 - 0.00035 20.6 0.0 0.00053 20.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ81498.1 - 0.00086 18.2 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 CDJ81498.1 - 0.0015 18.2 0.2 1.4 8.5 0.1 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 CDJ81498.1 - 0.015 14.9 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 CDJ81498.1 - 0.048 13.0 0.2 0.08 12.2 0.2 1.5 1 1 0 1 1 1 0 Kinase-like Peptidase_M8 PF01457.16 CDJ81499.1 - 5.8e-54 183.7 5.6 1e-53 182.8 5.6 1.3 1 1 0 1 1 1 1 Leishmanolysin Peptidase_M85 PF13678.6 CDJ81499.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 NFkB-p65-degrading zinc protease Peptidase_M8 PF01457.16 CDJ81500.1 - 1.7e-35 122.8 8.2 9.8e-22 77.3 6.0 2.4 2 0 0 2 2 2 2 Leishmanolysin Peptidase_M85 PF13678.6 CDJ81500.1 - 0.018 14.6 0.2 0.093 12.3 0.2 2.1 2 1 1 3 3 3 0 NFkB-p65-degrading zinc protease Motile_Sperm PF00635.26 CDJ81502.1 - 3.8e-15 55.7 0.8 3.8e-15 55.7 0.8 2.4 2 1 0 2 2 1 1 MSP (Major sperm protein) domain Zip PF02535.22 CDJ81502.1 - 0.00068 19.0 6.8 0.0007 18.9 6.8 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Presenilin PF01080.17 CDJ81502.1 - 0.021 13.6 16.4 0.025 13.3 16.4 1.2 1 0 0 1 1 1 0 Presenilin CLN3 PF02487.17 CDJ81502.1 - 0.026 13.6 7.6 0.033 13.3 7.1 1.5 1 1 0 1 1 1 0 CLN3 protein V_ATPase_I PF01496.19 CDJ81502.1 - 0.03 12.3 11.7 0.042 11.8 11.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BSP_II PF05432.11 CDJ81502.1 - 0.035 13.8 28.0 0.045 13.5 28.0 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF4228 PF14009.6 CDJ81502.1 - 0.067 13.6 9.2 0.09 13.2 8.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4228) Nop14 PF04147.12 CDJ81502.1 - 0.086 11.0 29.1 0.1 10.8 29.1 1.1 1 0 0 1 1 1 0 Nop14-like family SID-1_RNA_chan PF13965.6 CDJ81502.1 - 0.1 11.0 1.7 0.14 10.5 1.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CDC45 PF02724.14 CDJ81502.1 - 0.23 9.7 22.6 0.27 9.5 22.6 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 CDJ81502.1 - 0.26 10.0 26.5 0.37 9.5 26.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SLC12 PF03522.15 CDJ81502.1 - 0.29 10.1 16.2 0.37 9.8 16.2 1.2 1 0 0 1 1 1 0 Solute carrier family 12 AF-4 PF05110.13 CDJ81502.1 - 0.91 7.5 27.4 1.1 7.3 27.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Peptidase_S64 PF08192.11 CDJ81502.1 - 0.92 7.9 11.9 1.1 7.7 11.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 BT1 PF03092.16 CDJ81502.1 - 1 7.5 2.1 1.4 7.1 2.1 1.2 1 0 0 1 1 1 0 BT1 family Borrelia_P83 PF05262.11 CDJ81502.1 - 1 7.8 28.2 1.3 7.4 28.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein MMM1 PF10296.9 CDJ81502.1 - 1.6 7.7 8.0 3.4 6.6 8.0 1.6 1 1 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 DUF4551 PF15087.6 CDJ81502.1 - 1.9 7.2 16.4 2.5 6.9 16.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PA26 PF04636.13 CDJ81502.1 - 2.3 7.0 8.2 2.6 6.9 8.2 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) ASC PF00858.24 CDJ81502.1 - 2.5 7.0 6.5 3.8 6.4 6.5 1.3 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel SOBP PF15279.6 CDJ81502.1 - 2.5 8.6 9.0 3.2 8.3 9.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF5427 PF10310.9 CDJ81502.1 - 2.7 6.9 26.0 3.5 6.5 26.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Otopetrin PF03189.13 CDJ81502.1 - 3.6 6.3 4.4 5.2 5.8 4.4 1.2 1 0 0 1 1 1 0 Otopetrin Raftlin PF15250.6 CDJ81502.1 - 4.1 6.1 17.2 5.3 5.7 17.2 1.1 1 0 0 1 1 1 0 Raftlin DUF2151 PF10221.9 CDJ81502.1 - 4.4 5.8 19.4 5.3 5.5 19.4 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Smg8_Smg9 PF10220.9 CDJ81502.1 - 7.5 4.7 13.2 8.5 4.5 13.2 1.2 1 0 0 1 1 1 0 Smg8_Smg9 Connexin PF00029.19 CDJ81502.1 - 7.7 6.2 26.3 0.07 12.9 12.7 2.2 1 1 1 2 2 2 0 Connexin LAP1C PF05609.12 CDJ81502.1 - 8.9 5.3 19.3 11 4.9 19.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Dsh_C PF12316.8 CDJ81502.1 - 9.5 6.6 7.6 13 6.1 7.6 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Peptidase_M8 PF01457.16 CDJ81503.1 - 4.2e-08 32.3 0.0 5e-08 32.1 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 CDJ81504.1 - 1.8e-28 99.5 4.3 1.8e-19 69.9 0.0 2.0 1 1 1 2 2 2 2 Leishmanolysin Motile_Sperm PF00635.26 CDJ81505.1 - 1.5e-14 53.8 1.2 1.5e-14 53.8 1.2 3.2 3 2 0 3 3 3 1 MSP (Major sperm protein) domain RRM_1 PF00076.22 CDJ81506.1 - 2.2e-22 78.7 0.0 3.3e-10 39.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Motile_Sperm PF00635.26 CDJ81507.1 - 4.2e-15 55.5 0.4 4.2e-15 55.5 0.4 2.1 2 1 0 2 2 2 1 MSP (Major sperm protein) domain SVA PF05326.11 CDJ81507.1 - 0.18 11.8 0.1 0.43 10.6 0.0 1.6 2 0 0 2 2 2 0 Seminal vesicle autoantigen (SVA) FAM176 PF14851.6 CDJ81507.1 - 5.1 6.8 5.6 0.58 9.8 0.9 1.9 2 0 0 2 2 2 0 FAM176 family Paf1 PF03985.13 CDJ81508.1 - 1.8e-118 396.2 14.0 2.2e-118 395.9 14.0 1.1 1 0 0 1 1 1 1 Paf1 DARPP-32 PF05395.12 CDJ81508.1 - 5.6 7.2 21.1 0.19 12.0 14.2 2.1 3 0 0 3 3 3 0 Protein phosphatase inhibitor 1/DARPP-32 Ribosomal_S21 PF01165.20 CDJ81509.1 - 2.6e-13 49.5 0.0 4.2e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 Metallophos PF00149.28 CDJ81511.1 - 6.9e-20 72.4 2.8 8.4e-20 72.1 2.8 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDJ81511.1 - 5.1e-07 30.0 0.7 3.8e-06 27.2 0.7 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Cation_efflux PF01545.21 CDJ81512.1 - 0.054 13.2 4.6 0.085 12.6 4.6 1.2 1 0 0 1 1 1 0 Cation efflux family Mtp PF03821.16 CDJ81512.1 - 0.12 12.0 8.3 0.31 10.6 0.3 2.1 1 1 1 2 2 2 0 Golgi 4-transmembrane spanning transporter DUF4728 PF15860.5 CDJ81512.1 - 0.17 12.6 10.9 0.59 10.9 10.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4728) DUF3995 PF13160.6 CDJ81512.1 - 0.85 10.0 5.4 2.4 8.6 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) TFIIA PF03153.13 CDJ81513.1 - 9.9 6.0 9.6 11 5.8 9.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UnbV_ASPIC PF07593.12 CDJ81515.1 - 0.016 15.2 0.1 0.029 14.3 0.1 1.4 1 0 0 1 1 1 0 ASPIC and UnbV Ion_trans PF00520.31 CDJ81516.1 - 4.4e-36 124.4 9.1 6e-36 123.9 9.1 1.2 1 0 0 1 1 1 1 Ion transport protein PAS_9 PF13426.7 CDJ81516.1 - 2.7e-18 66.1 0.0 6.9e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 PAS domain cNMP_binding PF00027.29 CDJ81516.1 - 4.7e-12 45.8 0.0 1.1e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 CDJ81516.1 - 9.8e-09 35.1 1.4 9.8e-09 35.1 1.4 2.4 3 0 0 3 3 3 1 Ion channel PAS PF00989.25 CDJ81516.1 - 3e-07 30.4 0.0 6.8e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 CDJ81516.1 - 3.6e-07 30.4 0.0 9.8e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 CDJ81516.1 - 4.1e-05 23.8 0.0 0.00014 22.0 0.0 1.9 2 0 0 2 2 2 1 PAS fold Cupin_2 PF07883.11 CDJ81516.1 - 0.017 14.8 0.1 0.035 13.8 0.1 1.4 1 0 0 1 1 1 0 Cupin domain Na_H_Exchanger PF00999.21 CDJ81517.1 - 1.2e-35 123.1 30.8 1.2e-35 123.1 30.8 1.8 2 1 0 2 2 2 1 Sodium/hydrogen exchanger family RseC_MucC PF04246.12 CDJ81517.1 - 0.28 11.1 7.8 0.53 10.2 0.3 3.7 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC WBP-1 PF11669.8 CDJ81518.1 - 0.0017 18.9 0.7 0.0033 18.0 0.7 1.5 1 0 0 1 1 1 1 WW domain-binding protein 1 MAP17 PF15807.5 CDJ81518.1 - 0.0032 17.7 0.0 0.0049 17.1 0.0 1.3 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 PRIMA1 PF16101.5 CDJ81518.1 - 0.013 15.5 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 EphA2_TM PF14575.6 CDJ81518.1 - 0.043 14.7 0.0 0.091 13.6 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM52 PF14979.6 CDJ81518.1 - 0.081 12.8 0.7 0.16 11.9 0.7 1.5 1 0 0 1 1 1 0 Transmembrane 52 DUF3377 PF11857.8 CDJ81518.1 - 0.13 12.2 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF4381 PF14316.6 CDJ81518.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TMEM132D_C PF15706.5 CDJ81518.1 - 3.8 7.4 5.7 1.4 8.8 2.0 2.0 1 1 1 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term ECSCR PF15820.5 CDJ81519.1 - 0.12 12.3 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator TIL PF01826.17 CDJ81520.1 - 7.5e-08 32.5 15.8 7.5e-08 32.5 15.8 2.2 2 0 0 2 2 2 1 Trypsin Inhibitor like cysteine rich domain TIL PF01826.17 CDJ81521.1 - 5.5e-42 141.8 130.3 2e-11 44.0 20.8 9.7 7 1 3 10 10 10 5 Trypsin Inhibitor like cysteine rich domain TIL PF01826.17 CDJ81522.1 - 5.9e-37 125.7 123.2 2.1e-12 47.1 16.8 9.6 7 3 1 8 8 8 5 Trypsin Inhibitor like cysteine rich domain cEGF PF12662.7 CDJ81522.1 - 0.0004 20.2 31.4 1.2 9.2 0.6 7.5 5 0 0 5 5 5 5 Complement Clr-like EGF-like G2F PF07474.12 CDJ81523.1 - 6.9e-53 179.2 0.0 1.1e-52 178.5 0.0 1.4 1 0 0 1 1 1 1 G2F domain EGF_3 PF12947.7 CDJ81523.1 - 2e-48 162.3 211.1 2.8e-10 40.2 12.6 13.8 13 0 0 13 13 13 12 EGF domain Ldl_recept_b PF00058.17 CDJ81523.1 - 1.6e-25 89.3 5.8 4.8e-06 27.0 0.0 5.5 5 0 0 5 5 5 4 Low-density lipoprotein receptor repeat class B cEGF PF12662.7 CDJ81523.1 - 1.1e-14 54.1 109.6 4.4e-05 23.3 0.3 13.3 13 0 0 13 13 13 9 Complement Clr-like EGF-like EGF PF00008.27 CDJ81523.1 - 2e-14 53.5 191.3 0.00027 21.2 7.4 14.1 14 0 0 14 14 13 10 EGF-like domain EGF_CA PF07645.15 CDJ81523.1 - 1.6e-11 44.2 19.4 4.6e-11 42.7 10.7 13.2 12 1 1 13 13 12 7 Calcium-binding EGF domain EGF_MSP1_1 PF12946.7 CDJ81523.1 - 4.5e-09 36.2 148.4 0.0005 20.1 4.6 12.6 12 0 0 12 12 11 8 MSP1 EGF domain 1 FXa_inhibition PF14670.6 CDJ81523.1 - 1.4e-05 25.2 5.0 1.4e-05 25.2 5.0 14.1 14 0 0 14 14 13 4 Coagulation Factor Xa inhibitory site SGL PF08450.12 CDJ81523.1 - 0.00024 20.8 0.8 0.28 10.7 0.8 3.8 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region hEGF PF12661.7 CDJ81523.1 - 0.0018 18.8 17.0 0.0027 18.3 4.2 15.9 16 1 0 16 16 13 6 Human growth factor-like EGF DUF5050 PF16472.5 CDJ81523.1 - 0.02 14.1 0.1 0.065 12.5 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5050) NHL PF01436.21 CDJ81523.1 - 0.038 14.0 3.9 4.5 7.5 0.0 4.1 4 0 0 4 4 4 0 NHL repeat Clc-like PF07062.12 CDJ81525.1 - 0.0098 15.4 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 1 Clc-like Ground-like PF04155.18 CDJ81526.1 - 7e-22 77.9 0.3 1e-21 77.4 0.3 1.2 1 0 0 1 1 1 1 Ground-like domain Cadherin_C_2 PF16492.5 CDJ81528.1 - 0.021 15.5 0.0 0.052 14.3 0.0 1.7 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal WBP-1 PF11669.8 CDJ81528.1 - 0.023 15.3 0.0 0.052 14.2 0.0 1.5 1 0 0 1 1 1 0 WW domain-binding protein 1 Hormone_recep PF00104.30 CDJ81529.1 - 3.8e-44 150.7 4.2 5.9e-44 150.1 4.2 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 CDJ81529.1 - 1.9e-21 76.3 10.7 3.7e-21 75.3 10.7 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) TraE PF05309.11 CDJ81529.1 - 0.045 13.1 0.0 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 TraE protein ARL2_Bind_BART PF11527.8 CDJ81530.1 - 1.5e-21 76.7 0.0 3.3e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Pneumo_att_G PF05539.11 CDJ81530.1 - 3.1 7.3 20.2 4.8 6.7 20.2 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Peptidase_A17 PF05380.13 CDJ81531.1 - 4.7e-45 153.5 0.7 1e-44 152.4 0.7 1.6 1 0 0 1 1 1 1 Pao retrotransposon peptidase RVT_1 PF00078.27 CDJ81531.1 - 2.4e-07 30.5 0.1 5.2e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDJ81531.1 - 0.0003 20.8 0.0 0.0029 17.6 0.1 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ81531.1 - 0.0035 17.6 0.1 0.019 15.2 0.1 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Talin_middle PF09141.10 CDJ81531.1 - 0.05 13.6 0.7 0.18 11.8 0.2 2.1 2 0 0 2 2 2 0 Talin, middle domain ATP12 PF07542.11 CDJ81531.1 - 0.095 12.8 1.0 4.2 7.5 0.0 3.0 3 0 0 3 3 3 0 ATP12 chaperone protein DUF16 PF01519.16 CDJ81531.1 - 0.52 10.8 4.3 11 6.6 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function DUF16 BLOC1_2 PF10046.9 CDJ81531.1 - 2.1 8.7 5.5 0.47 10.8 0.1 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SRP54 PF00448.22 CDJ81532.1 - 8.1e-51 172.4 0.1 1.8e-50 171.3 0.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 CDJ81532.1 - 1.4e-48 166.4 7.7 1.9e-48 165.9 7.7 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 CDJ81532.1 - 9.2e-10 38.6 0.2 3.9e-09 36.6 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 CDJ81532.1 - 7.1e-05 21.9 0.0 0.0002 20.4 0.0 1.7 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 CDJ81532.1 - 0.00056 19.7 0.1 0.00099 18.9 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CDJ81532.1 - 0.00078 19.9 0.5 0.014 15.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CDJ81532.1 - 0.0025 18.2 0.0 0.0075 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 CDJ81532.1 - 0.0037 17.3 0.8 0.78 9.8 0.0 3.0 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 CDJ81532.1 - 0.0046 17.2 0.0 0.02 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CDJ81532.1 - 0.0069 16.5 0.2 0.024 14.7 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase ArsA_ATPase PF02374.15 CDJ81532.1 - 0.013 14.7 0.3 0.053 12.7 0.0 2.0 2 0 0 2 2 2 0 Anion-transporting ATPase AAA_33 PF13671.6 CDJ81532.1 - 0.036 14.2 0.0 0.077 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CDJ81532.1 - 0.05 12.9 0.0 0.14 11.4 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 CDJ81532.1 - 0.055 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase ABC_tran PF00005.27 CDJ81532.1 - 0.066 13.7 0.0 0.23 12.0 0.0 1.9 2 0 0 2 2 1 0 ABC transporter Longin PF13774.6 CDJ81532.1 - 0.13 12.3 0.4 0.29 11.2 0.4 1.5 1 0 0 1 1 1 0 Regulated-SNARE-like domain SRX PF09201.10 CDJ81532.1 - 0.15 11.9 1.6 0.25 11.2 0.3 2.1 2 0 0 2 2 2 0 SRX, signal recognition particle receptor alpha subunit Ank_2 PF12796.7 CDJ81533.1 - 0.00096 19.7 0.1 0.0018 18.8 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDJ81533.1 - 0.015 15.8 0.2 10 7.1 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat DUF3484 PF11983.8 CDJ81533.1 - 0.42 11.7 2.7 0.65 11.2 0.0 2.5 3 0 0 3 3 3 0 Membrane-attachment and polymerisation-promoting switch ATPgrasp_Ter PF15632.6 CDJ81534.1 - 0.075 12.8 0.0 0.18 11.5 0.0 1.5 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon RGS PF00615.19 CDJ81536.1 - 1.8e-29 102.4 0.4 2.3e-29 102.1 0.4 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS-like PF09128.11 CDJ81536.1 - 0.0016 18.2 0.1 0.0021 17.8 0.1 1.3 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain RVT_1 PF00078.27 CDJ81537.1 - 3.1e-08 33.4 0.0 4.4e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDJ81537.1 - 3.2e-05 23.8 0.0 7.4e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ81537.1 - 5.8e-05 22.7 0.0 8.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4704 PF15787.5 CDJ81538.1 - 0.0008 18.7 0.1 0.0033 16.7 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4704) Chromo PF00385.24 CDJ81539.1 - 4.8e-14 52.0 0.3 1.3e-13 50.6 0.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 CDJ81539.1 - 0.12 12.5 0.1 0.27 11.4 0.1 1.6 1 0 0 1 1 1 0 Chromo shadow domain RRM_1 PF00076.22 CDJ81540.1 - 1.5e-09 37.5 0.3 1.4e-07 31.2 0.0 3.4 3 1 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_4 PF12799.7 CDJ81540.1 - 1.8e-09 37.7 20.5 0.064 13.7 0.0 7.4 5 2 4 9 9 9 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ81540.1 - 0.00029 20.5 13.7 3.9 7.3 0.2 6.4 6 1 0 6 6 6 3 Leucine rich repeat LRR_6 PF13516.6 CDJ81540.1 - 5.6 7.3 22.5 51 4.3 0.0 8.3 9 0 0 9 9 9 0 Leucine Rich repeat O-FucT PF10250.9 CDJ81541.1 - 5e-63 213.8 0.0 5.8e-63 213.6 0.0 1.0 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Peptidase_C12 PF01088.21 CDJ81542.1 - 5.4e-57 192.9 0.0 8.2e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 CDJ81542.1 - 8.8e-20 70.4 1.2 1.8e-19 69.4 1.2 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases ShK PF01549.24 CDJ81543.1 - 1.7e-07 31.6 2.2 2.3e-07 31.2 2.2 1.3 1 0 0 1 1 1 1 ShK domain-like PLAC PF08686.11 CDJ81543.1 - 0.039 14.7 2.0 0.084 13.6 2.0 1.7 1 1 0 1 1 1 0 PLAC (protease and lacunin) domain Glucosamine_iso PF01182.20 CDJ81544.1 - 2.1e-22 80.1 0.0 3.3e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PI_PP_I PF18363.1 CDJ81545.1 - 0.036 14.2 0.0 0.079 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain COX8 PF02285.15 CDJ81546.1 - 0.02 14.7 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII Peptidase_M1 PF01433.20 CDJ81548.1 - 1.2e-49 168.8 0.6 2.2e-49 168.0 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 CDJ81548.1 - 1.3e-44 153.1 0.0 1.8e-44 152.6 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CDJ81548.1 - 1.3e-34 120.0 0.1 5.7e-33 114.7 0.0 2.3 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain LuxQ-periplasm PF09308.10 CDJ81548.1 - 0.089 12.3 0.5 0.15 11.5 0.5 1.2 1 0 0 1 1 1 0 LuxQ, periplasmic RNR_N PF08343.10 CDJ81548.1 - 0.13 12.3 1.5 1.2 9.3 0.2 2.7 1 1 1 2 2 2 0 Ribonucleotide reductase N-terminal DUF4837 PF16125.5 CDJ81548.1 - 0.18 10.8 3.6 0.2 10.6 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4837) RVT_1 PF00078.27 CDJ81549.1 - 2.4e-12 46.9 0.0 4.5e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5305 PF17231.2 CDJ81550.1 - 0.054 12.9 0.0 0.061 12.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF4307 PF14155.6 CDJ81550.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) US6 PF17616.2 CDJ81550.1 - 8 6.4 5.8 22 5.0 0.2 2.1 1 1 1 2 2 2 0 Viral unique short region 6 Exo_endo_phos_2 PF14529.6 CDJ81551.1 - 4.7e-06 26.4 0.0 7.6e-06 25.8 0.0 1.3 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Y_phosphatase PF00102.27 CDJ81552.1 - 0.042 13.4 0.0 0.054 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Hormone_recep PF00104.30 CDJ81553.1 - 2.5e-08 33.8 0.1 2.6e-08 33.7 0.1 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Cas_Csy4 PF09618.10 CDJ81555.1 - 0.052 13.7 0.1 0.067 13.3 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Fib_alpha PF08702.10 CDJ81556.1 - 0.16 12.1 3.2 0.15 12.2 1.6 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4661 PF15576.6 CDJ81556.1 - 5 7.0 11.4 0.17 11.8 3.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4661) UPF0242 PF06785.11 CDJ81556.1 - 9.7 6.2 14.2 0.083 13.0 4.8 2.2 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ABC_membrane_2 PF06472.15 CDJ81557.1 - 0.024 14.1 0.1 0.044 13.2 0.1 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 YiaAB PF05360.14 CDJ81557.1 - 6.5 7.1 11.1 0.88 9.9 1.3 3.9 3 1 1 4 4 4 0 yiaA/B two helix domain Lectin_C PF00059.21 CDJ81558.1 - 4.3e-38 130.4 4.9 3.5e-18 66.3 0.6 2.2 2 0 0 2 2 2 2 Lectin C-type domain Xlink PF00193.17 CDJ81558.1 - 0.00065 20.0 1.2 0.34 11.3 0.1 2.9 2 1 0 2 2 2 2 Extracellular link domain CBM_14 PF01607.24 CDJ81558.1 - 3.7 7.8 7.9 2.2 8.5 0.1 3.3 3 0 0 3 3 3 0 Chitin binding Peritrophin-A domain Lectin_C PF00059.21 CDJ81559.1 - 5.2e-33 114.0 11.0 3.6e-17 63.0 1.0 2.1 2 0 0 2 2 2 2 Lectin C-type domain Lectin_C PF00059.21 CDJ81560.1 - 1.7e-34 118.8 8.1 2.1e-17 63.8 3.8 2.1 2 0 0 2 2 2 2 Lectin C-type domain Intimin_C PF07979.11 CDJ81560.1 - 0.93 10.0 5.8 1.3 9.5 0.7 2.8 3 0 0 3 3 3 0 Intimin C-type lectin domain SprT-like PF10263.9 CDJ81562.1 - 2.2e-22 79.0 0.0 4.9e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 CDJ81562.1 - 0.0032 17.4 4.0 0.0032 17.4 4.0 2.1 2 0 0 2 2 2 1 SprT-like zinc ribbon domain Herpes_UL73 PF03554.13 CDJ81562.1 - 0.18 11.8 0.0 0.49 10.4 0.0 1.7 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein zf-CHY PF05495.12 CDJ81562.1 - 1.3 9.6 5.2 29 5.2 2.7 2.7 2 0 0 2 2 2 0 CHY zinc finger Pyridoxal_deC PF00282.19 CDJ81563.1 - 2.3e-77 260.2 0.3 3.3e-77 259.7 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 CDJ81563.1 - 0.0016 17.7 0.1 0.0038 16.4 0.1 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II HdeA PF06411.11 CDJ81563.1 - 0.18 12.0 0.5 0.42 10.8 0.5 1.6 1 0 0 1 1 1 0 HdeA/HdeB family Pkinase_Tyr PF07714.17 CDJ81567.1 - 2.4e-77 259.7 0.0 8.3e-77 258.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ81567.1 - 6.9e-39 133.8 0.0 8.6e-38 130.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CDJ81567.1 - 0.053 12.3 0.0 0.079 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CDJ81567.1 - 0.097 12.6 0.0 3 7.7 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family BAH PF01426.18 CDJ81569.1 - 1.1e-27 96.2 0.0 3.7e-27 94.6 0.0 1.9 1 1 0 1 1 1 1 BAH domain ELM2 PF01448.24 CDJ81569.1 - 2.9e-14 53.6 1.7 3.2e-13 50.2 0.1 3.4 3 1 0 3 3 3 1 ELM2 domain MTA_R1 PF17226.2 CDJ81569.1 - 3.9e-09 36.5 2.5 1.5e-08 34.7 2.5 2.0 1 0 0 1 1 1 1 MTA R1 domain Myb_DNA-binding PF00249.31 CDJ81569.1 - 3.2e-05 24.0 0.1 0.00014 22.0 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain GATA PF00320.27 CDJ81569.1 - 0.00042 19.9 5.4 0.00083 18.9 5.4 1.5 1 0 0 1 1 1 1 GATA zinc finger Myb_DNA-bind_7 PF15963.5 CDJ81569.1 - 0.014 15.3 0.4 0.04 13.8 0.4 1.8 1 0 0 1 1 1 0 Myb DNA-binding like Macoilin PF09726.9 CDJ81572.1 - 8.7 4.8 20.4 11 4.5 20.4 1.1 1 0 0 1 1 1 0 Macoilin family Peptidase_M13_N PF05649.13 CDJ81573.1 - 2.6e-96 323.6 0.6 4e-96 323.0 0.6 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 CDJ81573.1 - 9.6e-70 234.3 0.1 2.6e-69 232.9 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M4 PF01447.18 CDJ81573.1 - 0.017 15.6 0.7 0.054 14.0 0.7 1.9 1 1 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain SAS-6_N PF16531.5 CDJ81574.1 - 1.1e-05 26.0 0.0 0.17 12.5 0.0 2.5 2 0 0 2 2 2 2 Centriolar protein SAS N-terminal ASXH PF13919.6 CDJ81574.1 - 0.0018 18.3 2.8 1.6 8.8 0.0 3.9 2 1 1 3 3 3 1 Asx homology domain GAT PF03127.14 CDJ81574.1 - 0.012 15.9 0.0 2.6 8.4 0.0 2.5 2 0 0 2 2 2 0 GAT domain Cas_Csy3 PF09615.10 CDJ81574.1 - 0.016 14.6 0.1 3.4 6.9 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy3) Cbl_N PF02262.16 CDJ81574.1 - 0.019 15.0 0.3 4.2 7.4 0.0 2.7 3 0 0 3 3 3 0 CBL proto-oncogene N-terminal domain 1 CLU PF13236.6 CDJ81574.1 - 0.023 14.5 0.3 6.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Clustered mitochondria C6 PF01681.17 CDJ81577.1 - 1.4e-06 28.7 0.4 1.8e-06 28.4 0.4 1.2 1 0 0 1 1 1 1 C6 domain Antistasin PF02822.14 CDJ81577.1 - 0.66 10.7 3.8 9.3 7.0 0.2 2.7 2 0 0 2 2 2 0 Antistasin family C6 PF01681.17 CDJ81578.1 - 1.5e-05 25.4 0.1 2.1e-05 25.0 0.1 1.2 1 1 0 1 1 1 1 C6 domain Antistasin PF02822.14 CDJ81578.1 - 0.32 11.7 2.8 14 6.4 0.2 2.6 2 0 0 2 2 2 0 Antistasin family Cation_efflux PF01545.21 CDJ81580.1 - 1.1e-46 159.1 18.3 1.3e-46 158.9 18.3 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 CDJ81580.1 - 0.069 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter DAP_B PF07930.12 CDJ81582.1 - 2.1 8.3 5.3 0.81 9.6 1.1 2.1 1 1 2 3 3 3 0 D-aminopeptidase, domain B GF_recep_IV PF14843.6 CDJ81582.1 - 6 6.7 23.5 3 7.6 10.8 2.2 1 1 1 2 2 2 0 Growth factor receptor domain IV Collagen PF01391.18 CDJ81583.1 - 4.5e-38 128.8 105.5 3.3e-10 39.6 23.4 4.2 1 1 3 4 4 4 4 Collagen triple helix repeat (20 copies) DUF4349 PF14257.6 CDJ81583.1 - 0.21 11.0 0.2 0.28 10.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) AT_hook PF02178.19 CDJ81584.1 - 0.031 14.1 65.5 0.2 11.6 4.7 6.7 6 0 0 6 6 6 0 AT hook motif DUF3246 PF11596.8 CDJ81584.1 - 0.14 11.5 2.8 0.14 11.5 1.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) BTB PF00651.31 CDJ81585.1 - 0.00058 20.1 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Slx4 PF09494.10 CDJ81585.1 - 0.025 14.5 0.0 0.064 13.2 0.0 1.7 1 0 0 1 1 1 0 Slx4 endonuclease SAP PF02037.27 CDJ81585.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 SAP domain LEM PF03020.15 CDJ81585.1 - 0.14 11.8 0.0 0.43 10.2 0.0 1.9 1 0 0 1 1 1 0 LEM domain DUF108 PF01958.18 CDJ81586.1 - 1.6e-20 73.2 0.0 2.9e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF108 NAD_binding_3 PF03447.16 CDJ81586.1 - 1.3e-09 38.8 0.0 2.3e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 CDJ81586.1 - 0.017 15.2 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 CDJ81586.1 - 0.022 14.8 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 CDJ81586.1 - 0.03 15.1 0.0 0.058 14.2 0.0 1.6 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold 2-Hacid_dh_C PF02826.19 CDJ81586.1 - 0.039 13.3 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.15 CDJ81586.1 - 0.04 12.9 0.0 0.064 12.2 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Sacchrp_dh_NADP PF03435.18 CDJ81586.1 - 0.1 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 CDJ81586.1 - 0.11 13.1 0.0 0.19 12.4 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Gp_dh_N PF00044.24 CDJ81586.1 - 0.11 12.9 0.1 0.67 10.3 0.0 2.3 2 1 1 3 3 3 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 CDJ81586.1 - 0.17 12.0 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Gp-FAR-1 PF05823.12 CDJ81587.1 - 1e-15 58.4 2.6 1.5e-15 57.8 2.6 1.3 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF2205 PF10224.9 CDJ81587.1 - 0.027 14.5 0.1 0.25 11.3 0.0 2.5 2 1 0 2 2 2 0 Short coiled-coil protein HPPK PF01288.20 CDJ81587.1 - 0.1 13.1 0.5 1.2 9.7 0.0 2.2 2 0 0 2 2 2 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) SCVP PF17619.2 CDJ81588.1 - 1.2e-15 58.2 0.0 1.6e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Secreted clade V proteins SCVP PF17619.2 CDJ81589.1 - 7.5e-25 87.6 0.4 1e-24 87.2 0.4 1.2 1 0 0 1 1 1 1 Secreted clade V proteins 7TM_GPCR_Srd PF10317.9 CDJ81590.1 - 1.4e-20 73.7 3.6 1.9e-20 73.3 3.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Str PF10326.9 CDJ81590.1 - 9.4e-07 28.5 4.3 1.1e-06 28.3 4.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srj PF10319.9 CDJ81590.1 - 1.3e-05 24.7 2.9 1.6e-05 24.5 2.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Srh PF10318.9 CDJ81590.1 - 0.00017 20.7 2.1 0.0002 20.5 2.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh Kelch_1 PF01344.25 CDJ81591.1 - 1.4e-78 258.2 9.2 5.5e-17 61.1 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CDJ81591.1 - 7.8e-39 130.7 0.4 5.1e-08 32.9 0.0 6.4 2 2 4 6 6 6 6 Kelch motif BTB PF00651.31 CDJ81591.1 - 5.6e-28 97.4 1.0 1.1e-27 96.4 1.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 CDJ81591.1 - 6.3e-27 93.7 1.5 1.2e-26 92.8 1.5 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 CDJ81591.1 - 7.7e-24 83.5 5.1 8.4e-06 25.7 0.0 6.2 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 CDJ81591.1 - 2.7e-23 81.0 2.8 1.2e-05 25.1 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 CDJ81591.1 - 2.2e-16 59.7 6.7 0.0099 16.2 0.1 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain DUF3342 PF11822.8 CDJ81591.1 - 0.0082 16.3 0.9 0.11 12.7 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) Kelch_5 PF13854.6 CDJ81591.1 - 0.0095 15.9 8.5 2.9 8.0 0.0 5.1 6 0 0 6 6 6 2 Kelch motif THUMP PF02926.17 CDJ81592.1 - 6.1e-15 55.6 0.0 1.1e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 THUMP domain Hid1 PF12722.7 CDJ81593.1 - 4.6e-118 395.5 4.5 9.1e-72 242.4 0.6 2.0 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 CDJ81593.1 - 1.3e-113 380.7 0.0 1.4e-113 380.5 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein HECT_2 PF09814.9 CDJ81593.1 - 0.06 12.2 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding TMEM239 PF15841.5 CDJ81593.1 - 0.88 9.5 3.8 1.6 8.6 2.1 2.0 2 0 0 2 2 2 0 Transmembrane protein 239 family Hid1 PF12722.7 CDJ81594.1 - 3.6e-139 465.4 0.9 9e-139 464.0 0.9 1.5 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 CDJ81594.1 - 6.2e-103 345.4 0.0 6.9e-103 345.2 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein IFT81_CH PF18383.1 CDJ81594.1 - 0.0084 16.4 0.2 3 8.1 0.0 3.0 3 0 0 3 3 3 2 Intraflagellar transport 81 calponin homology domain PMAIP1 PF15150.6 CDJ81594.1 - 0.038 13.9 0.1 11 5.9 0.0 2.7 2 0 0 2 2 2 0 Phorbol-12-myristate-13-acetate-induced zf-RING_2 PF13639.6 CDJ81595.1 - 2.3e-07 31.0 7.4 2.3e-07 31.0 7.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 CDJ81595.1 - 0.00038 20.4 4.7 0.00038 20.4 4.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 CDJ81595.1 - 0.00076 19.7 7.5 0.00076 19.7 7.5 2.3 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CDJ81595.1 - 0.0027 17.4 1.3 0.0027 17.4 1.3 2.0 2 1 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 CDJ81595.1 - 0.0037 17.1 5.0 0.0037 17.1 5.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ81595.1 - 0.0038 17.2 1.4 0.0038 17.2 1.4 3.2 3 0 0 3 3 3 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 CDJ81595.1 - 0.0044 16.6 5.5 0.0044 16.6 5.5 2.4 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CDJ81595.1 - 0.081 13.0 12.1 0.093 12.8 10.3 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Molybdopterin PF00384.22 CDJ81596.1 - 3.1e-69 234.0 0.0 1.7e-68 231.5 0.0 1.9 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 CDJ81596.1 - 4.2e-17 62.0 0.1 8.3e-17 61.0 0.1 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 CDJ81596.1 - 1.2e-15 56.8 0.1 1.2e-15 56.8 0.1 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 CDJ81596.1 - 1.6e-10 41.5 0.0 4.4e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 CDJ81596.1 - 5e-07 29.6 0.4 5e-07 29.6 0.4 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain PAN_1 PF00024.26 CDJ81597.1 - 3.6e-28 97.4 11.4 1.3e-14 53.9 4.3 2.7 2 0 0 2 2 2 2 PAN domain PAN_4 PF14295.6 CDJ81597.1 - 0.00065 19.6 3.3 0.004 17.0 0.7 2.7 2 0 0 2 2 2 1 PAN domain PAN_2 PF08276.11 CDJ81597.1 - 0.066 13.3 0.7 0.066 13.3 0.7 2.6 2 0 0 2 2 2 0 PAN-like domain PLCC PF14466.6 CDJ81597.1 - 0.2 11.8 2.4 0.46 10.6 0.3 2.3 1 1 1 2 2 2 0 PLAT/LH2 and C2-like Ca2+-binding lipoprotein Neur_chan_memb PF02932.16 CDJ81600.1 - 0.0053 16.9 0.0 0.0056 16.8 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region PsbT PF01405.17 CDJ81600.1 - 5.1 7.0 7.2 9.1 6.2 7.2 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre T protein Neur_chan_LBD PF02931.23 CDJ81601.1 - 3.2e-31 108.5 3.1 8.8e-22 77.6 1.8 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ81601.1 - 7.6e-08 32.7 1.3 1.1e-07 32.1 1.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region BSD PF03909.17 CDJ81602.1 - 2.9e-12 46.4 0.6 5.9e-12 45.4 0.6 1.6 1 0 0 1 1 1 1 BSD domain JIP_LZII PF16471.5 CDJ81602.1 - 0.49 10.6 5.0 0.67 10.2 0.2 3.0 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II TFIIS_C PF01096.18 CDJ81603.1 - 1.2e-15 57.0 3.6 1.2e-15 57.0 3.6 3.2 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CDJ81603.1 - 2.8e-13 49.5 2.9 2.8e-13 49.5 2.9 2.5 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_ribbon_recom PF13408.6 CDJ81603.1 - 0.0001 22.8 5.3 0.003 18.0 0.3 2.2 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain TF_Zn_Ribbon PF08271.12 CDJ81603.1 - 0.003 17.1 5.6 0.2 11.2 0.1 3.5 3 1 0 3 3 3 1 TFIIB zinc-binding DZR PF12773.7 CDJ81603.1 - 0.0067 16.4 2.0 0.0067 16.4 2.0 2.4 2 1 1 3 3 3 1 Double zinc ribbon Lar_restr_allev PF14354.6 CDJ81603.1 - 0.0073 16.7 0.7 0.0073 16.7 0.7 2.4 2 1 0 2 2 2 1 Restriction alleviation protein Lar Ogr_Delta PF04606.12 CDJ81603.1 - 0.012 15.6 1.6 0.012 15.6 1.6 3.1 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger Zn_Tnp_IS1595 PF12760.7 CDJ81603.1 - 0.025 14.6 9.1 0.15 12.1 1.6 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain CpXC PF14353.6 CDJ81603.1 - 0.062 13.4 9.8 0.95 9.5 0.5 2.8 2 1 1 3 3 3 0 CpXC protein zf-C4_Topoisom PF01396.19 CDJ81603.1 - 0.079 12.8 6.0 0.65 9.8 0.7 2.4 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Ribosomal_S27e PF01667.17 CDJ81603.1 - 0.14 11.9 9.4 0.53 10.0 0.2 3.9 4 0 0 4 4 4 0 Ribosomal protein S27 DUF3268 PF11672.8 CDJ81603.1 - 0.21 12.0 5.5 4.7 7.6 0.5 2.3 2 0 0 2 2 2 0 zinc-finger-containing domain zf-ribbon_3 PF13248.6 CDJ81603.1 - 0.23 10.9 11.3 4 7.0 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain zf-IS66 PF13005.7 CDJ81603.1 - 0.3 11.5 12.2 0.8 10.2 0.4 3.5 2 2 1 3 3 3 0 zinc-finger binding domain of transposase IS66 zf_UBZ PF18439.1 CDJ81603.1 - 0.34 10.6 7.8 1.2 8.8 0.3 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Anti-TRAP PF15777.5 CDJ81603.1 - 0.38 10.8 4.3 0.58 10.2 0.1 2.6 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zinc_ribbon_2 PF13240.6 CDJ81603.1 - 0.45 10.3 10.1 2.2 8.1 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 CDJ81603.1 - 0.8 9.7 5.3 4.1 7.4 2.1 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-TFIIB PF13453.6 CDJ81603.1 - 0.98 8.8 5.3 7.8 5.9 0.1 2.5 2 0 0 2 2 2 0 Transcription factor zinc-finger Zn-ribbon_8 PF09723.10 CDJ81603.1 - 1.4 9.1 13.0 6.1 7.1 2.1 3.7 4 1 0 4 4 4 0 Zinc ribbon domain zinc_ribbon_10 PF10058.9 CDJ81603.1 - 2.4 7.9 8.0 1.1 9.1 2.1 2.9 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Nudix_N_2 PF14803.6 CDJ81603.1 - 2.9 7.9 12.9 11 6.0 4.4 3.1 2 2 0 2 2 2 0 Nudix N-terminal zf-ISL3 PF14690.6 CDJ81603.1 - 4.4 8.0 9.8 2.3 8.9 0.2 3.2 2 1 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_9 PF14369.6 CDJ81603.1 - 10 6.5 12.6 11 6.3 1.3 2.9 2 1 0 2 2 2 0 zinc-ribbon Robl_LC7 PF03259.17 CDJ81604.1 - 7.8e-11 41.6 0.1 1.3e-10 40.9 0.1 1.4 1 1 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 CDJ81604.1 - 0.0071 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 ADK PF00406.22 CDJ81606.1 - 0.12 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Adenylate kinase Mpv17_PMP22 PF04117.12 CDJ81607.1 - 1.6e-15 57.1 0.2 3.1e-15 56.1 0.2 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family 7TM_GPCR_Srx PF10328.9 CDJ81608.1 - 7.1e-09 35.7 18.9 1.2e-08 34.9 18.9 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2567 PF10821.8 CDJ81608.1 - 0.03 14.4 0.3 0.03 14.4 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2567) DUF5510 PF17629.2 CDJ81608.1 - 0.13 12.2 3.2 1.7 8.6 0.3 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5510) 7TM_GPCR_Srx PF10328.9 CDJ81609.1 - 5.1e-09 36.1 13.4 6.5e-09 35.8 13.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Sru PF10322.9 CDJ81609.1 - 0.00043 19.7 8.2 0.00063 19.2 8.2 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sru 7TM_GPCR_Srx PF10328.9 CDJ81610.1 - 3.3e-07 30.2 22.0 6.1e-07 29.3 22.0 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF5510 PF17629.2 CDJ81610.1 - 0.58 10.1 10.4 0.36 10.8 0.5 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5510) UPF0524 PF15823.5 CDJ81610.1 - 1.1 8.5 3.1 2 7.8 3.1 1.3 1 0 0 1 1 1 0 UPF0524 of C3orf70 MFS_1 PF07690.16 CDJ81611.1 - 4.9e-44 150.7 20.9 4.9e-44 150.7 20.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF5325 PF17259.2 CDJ81611.1 - 0.04 13.8 1.8 0.64 9.9 0.0 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5325) Shisa PF13908.6 CDJ81612.1 - 0.0026 18.1 0.1 0.0026 18.1 0.1 3.7 2 1 1 4 4 4 1 Wnt and FGF inhibitory regulator RIFIN PF02009.16 CDJ81612.1 - 0.004 17.1 2.8 0.86 9.4 0.0 2.3 2 0 0 2 2 2 2 Rifin LAP1C PF05609.12 CDJ81612.1 - 0.0045 16.1 6.0 0.0045 16.1 6.0 2.0 1 1 1 2 2 2 1 Lamina-associated polypeptide 1C (LAP1C) Mem_trans PF03547.18 CDJ81612.1 - 0.021 13.3 0.1 0.036 12.5 0.1 1.3 1 0 0 1 1 1 0 Membrane transport protein EphA2_TM PF14575.6 CDJ81612.1 - 0.059 14.2 2.0 0.11 13.5 0.6 2.2 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2561 PF10812.8 CDJ81612.1 - 0.098 12.7 0.1 0.098 12.7 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2561) DUF4808 PF16066.5 CDJ81612.1 - 0.11 13.1 1.6 0.29 11.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4808) DUF4834 PF16118.5 CDJ81612.1 - 0.5 11.3 0.1 0.5 11.3 0.1 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) SARAF PF06682.12 CDJ81613.1 - 0.0041 16.8 0.0 0.0046 16.7 0.0 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF2633 PF11119.8 CDJ81613.1 - 0.0066 16.3 0.1 0.0085 16.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2633) Syndecan PF01034.20 CDJ81613.1 - 0.12 12.3 0.2 0.16 11.9 0.2 1.2 1 0 0 1 1 1 0 Syndecan domain 7TM_GPCR_Srd PF10317.9 CDJ81614.1 - 1.6e-95 319.7 20.4 4.4e-71 239.5 17.7 2.0 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Str PF10326.9 CDJ81614.1 - 2.6e-24 86.1 19.3 5e-16 58.9 17.2 2.5 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srj PF10319.9 CDJ81614.1 - 3.6e-18 66.0 20.1 3.1e-11 43.2 14.7 2.4 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Srh PF10318.9 CDJ81614.1 - 5.3e-15 55.2 28.9 1.8e-12 46.9 18.9 2.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srh DUF2975 PF11188.8 CDJ81614.1 - 0.011 15.6 2.1 0.011 15.6 2.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) DUF3605 PF12239.8 CDJ81614.1 - 0.014 15.7 0.0 0.78 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3605) Rad17 PF03215.15 CDJ81614.1 - 0.025 14.5 1.5 4.4 7.2 0.1 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain COX6A PF02046.15 CDJ81614.1 - 0.059 13.8 0.4 7.3 7.1 0.1 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIa DUF1201 PF06716.11 CDJ81614.1 - 1.1 9.4 10.7 4.9 7.3 1.7 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1201) CC PF04942.14 CDJ81615.1 - 1.4e-13 50.8 149.7 0.00011 22.3 9.9 11.2 10 1 1 11 11 11 8 CC domain FARP PF01581.16 CDJ81616.1 - 0.00071 19.6 1.8 1.3 9.9 0.7 2.6 2 0 0 2 2 2 2 FMRFamide related peptide family CoaE PF01121.20 CDJ81617.1 - 6.2e-63 211.7 0.0 9.1e-63 211.2 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 CDJ81617.1 - 0.0028 18.2 0.0 0.012 16.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CDJ81617.1 - 0.13 12.5 0.0 0.47 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain MTH865 PF07747.11 CDJ81617.1 - 0.19 11.5 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 MTH865-like family zf-HC5HC2H_2 PF13832.6 CDJ81618.1 - 5.1e-28 97.4 7.3 5.1e-28 97.4 7.3 3.0 3 0 0 3 3 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CDJ81618.1 - 5.5e-21 74.6 5.9 5.5e-21 74.6 5.9 3.2 4 0 0 4 4 2 1 PHD-like zinc-binding domain PHD_2 PF13831.6 CDJ81618.1 - 1.2e-12 47.1 3.3 1.2e-12 47.1 3.3 2.3 2 0 0 2 2 1 1 PHD-finger PHD PF00628.29 CDJ81618.1 - 5.1e-08 32.7 9.2 5.1e-08 32.7 9.2 3.0 2 1 0 2 2 2 1 PHD-finger Spt20 PF12090.8 CDJ81618.1 - 0.019 14.6 26.6 0.042 13.5 26.6 1.5 1 0 0 1 1 1 0 Spt20 family EPL1 PF10513.9 CDJ81618.1 - 0.1 13.0 3.3 0.23 11.8 3.3 1.6 1 0 0 1 1 1 0 Enhancer of polycomb-like Sas6_CC PF18594.1 CDJ81618.1 - 0.11 12.3 1.5 0.24 11.2 1.5 1.5 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain FANCL_C PF11793.8 CDJ81618.1 - 0.45 10.7 13.1 4.3 7.6 5.5 2.6 2 0 0 2 2 2 0 FANCL C-terminal domain Anti-TRAP PF15777.5 CDJ81618.1 - 0.8 9.7 4.9 0.32 11.0 1.5 2.1 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein eIF-3_zeta PF05091.12 CDJ81618.1 - 0.88 8.5 10.3 1.3 7.9 10.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) V_ATPase_I PF01496.19 CDJ81618.1 - 1.2 6.9 10.2 1.9 6.3 10.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CAML PF14963.6 CDJ81618.1 - 1.5 8.9 4.8 0.34 11.0 1.2 1.7 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand TERB2 PF15101.6 CDJ81618.1 - 1.5 8.8 10.9 3.2 7.8 10.9 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 zf-RING-like PF08746.11 CDJ81618.1 - 2.1 8.7 10.3 5.2 7.5 3.0 2.9 2 0 0 2 2 2 0 RING-like domain CPSF100_C PF13299.6 CDJ81618.1 - 3.2 7.9 8.5 0.99 9.6 3.6 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF4770 PF15994.5 CDJ81618.1 - 8.2 6.6 13.2 1.4 9.1 9.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) HSP20 PF00011.21 CDJ81619.1 - 3e-07 30.5 0.0 3.4e-07 30.4 0.0 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF5640 PF18692.1 CDJ81619.1 - 0.015 15.3 0.0 0.016 15.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5640) ArsA_HSP20 PF17886.1 CDJ81619.1 - 0.06 12.9 0.1 0.081 12.5 0.1 1.3 1 1 0 1 1 1 0 HSP20-like domain found in ArsA LSM PF01423.22 CDJ81620.1 - 3.2e-18 65.2 0.0 4.5e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 CDJ81620.1 - 0.074 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 RimP C-terminal SH3 domain Atg8 PF02991.16 CDJ81621.1 - 1.3e-44 150.7 0.1 1.5e-44 150.4 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CDJ81621.1 - 4e-06 27.2 0.0 5.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Sde2_N_Ubi PF13019.6 CDJ81621.1 - 0.072 12.9 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain TB2_DP1_HVA22 PF03134.19 CDJ81622.1 - 0.083 12.8 0.8 0.21 11.5 0.1 2.0 1 1 0 2 2 2 0 TB2/DP1, HVA22 family TPR_14 PF13428.6 CDJ81622.1 - 0.1 13.5 0.1 0.22 12.5 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Fic PF02661.18 CDJ81623.1 - 3.1e-24 85.7 0.0 7e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 Fic/DOC family PBP PF01161.20 CDJ81624.1 - 1.7e-18 67.2 0.0 2.1e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PhoLip_ATPase_C PF16212.5 CDJ81625.1 - 1.1e-78 264.5 32.2 1.1e-78 264.5 32.2 2.8 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CDJ81625.1 - 1.8e-27 94.8 7.2 1.8e-27 94.8 7.2 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CDJ81625.1 - 8.4e-13 48.2 0.3 6.7e-11 42.1 0.0 2.7 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CDJ81625.1 - 2.9e-09 37.5 0.3 0.00019 21.8 0.0 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CDJ81625.1 - 9.5e-06 25.2 1.7 0.00011 21.7 0.0 2.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CDJ81625.1 - 0.0012 18.6 0.3 0.019 14.7 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Prominin PF05478.11 CDJ81625.1 - 3 5.7 5.8 0.44 8.4 0.5 1.9 2 0 0 2 2 2 0 Prominin zf-H2C2_2 PF13465.6 CDJ81626.1 - 2.4e-22 78.3 27.5 8e-08 32.4 2.3 5.5 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 CDJ81626.1 - 7.8e-20 70.2 30.4 4.1e-06 27.0 2.4 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ81626.1 - 4.7e-14 51.9 36.1 0.00015 22.3 1.5 6.0 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDJ81626.1 - 2.7e-10 40.0 22.9 0.0013 18.6 2.3 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ81626.1 - 1.9e-08 34.4 19.9 0.0011 19.2 0.0 5.4 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDJ81626.1 - 0.00017 21.9 19.0 0.0072 16.7 0.5 4.2 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-BED PF02892.15 CDJ81626.1 - 0.0025 17.8 25.1 0.066 13.2 4.7 4.9 2 1 3 5 5 5 2 BED zinc finger zf-C2HC_2 PF13913.6 CDJ81626.1 - 0.0056 16.6 17.7 1.4 8.9 1.0 4.8 4 0 0 4 4 4 2 zinc-finger of a C2HC-type Prok-RING_1 PF14446.6 CDJ81626.1 - 0.0064 16.4 13.7 6.3 6.8 0.0 4.8 5 0 0 5 5 4 0 Prokaryotic RING finger family 1 zf-CHCC PF10276.9 CDJ81626.1 - 0.014 15.4 13.2 0.38 10.8 0.3 4.2 4 0 0 4 4 4 0 Zinc-finger domain zf-Di19 PF05605.12 CDJ81626.1 - 0.023 15.0 5.0 0.023 15.0 5.0 3.3 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 CDJ81626.1 - 0.027 15.1 14.5 5 7.8 1.8 3.9 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zinc_ribbon_15 PF17032.5 CDJ81626.1 - 0.047 14.4 13.3 1.6 9.5 1.1 3.3 1 1 3 4 4 4 0 zinc-ribbon family Ribosomal_L31 PF01197.18 CDJ81626.1 - 0.062 13.5 2.7 1.4 9.2 0.5 3.1 1 1 1 2 2 2 0 Ribosomal protein L31 BolA PF01722.18 CDJ81626.1 - 0.11 12.8 5.1 4.5 7.6 0.0 3.2 2 1 0 2 2 2 0 BolA-like protein PyrI_C PF02748.15 CDJ81626.1 - 0.13 12.2 11.8 1.3 9.0 0.1 4.5 5 0 0 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Ta0938 PF11494.8 CDJ81626.1 - 0.16 12.3 5.4 0.86 9.9 0.1 3.2 1 1 2 3 3 3 0 Ta0938 Cript PF10235.9 CDJ81626.1 - 0.18 12.4 16.2 2.7 8.6 2.8 3.1 1 1 2 3 3 3 0 Microtubule-associated protein CRIPT HNH PF01844.23 CDJ81626.1 - 0.33 11.2 14.6 1.6 8.9 0.7 4.7 4 0 0 4 4 4 0 HNH endonuclease zf_UBZ PF18439.1 CDJ81626.1 - 0.47 10.1 14.9 6.1 6.5 0.3 4.9 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger YhfH PF14149.6 CDJ81626.1 - 0.52 10.3 8.9 10 6.2 0.3 4.3 3 1 1 4 4 4 0 YhfH-like protein DUF2256 PF10013.9 CDJ81626.1 - 0.72 10.0 12.4 28 4.9 0.3 4.5 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) Elf1 PF05129.13 CDJ81626.1 - 0.77 9.8 17.8 2.1 8.5 4.7 3.5 1 1 3 4 4 4 0 Transcription elongation factor Elf1 like Desulfoferrod_N PF06397.12 CDJ81626.1 - 0.85 9.3 10.1 9 6.0 0.0 4.1 4 0 0 4 4 4 0 Desulfoferrodoxin, N-terminal domain Zn-ribbon_8 PF09723.10 CDJ81626.1 - 0.91 9.7 20.8 3.3 7.9 3.6 4.2 3 1 1 5 5 4 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 CDJ81626.1 - 1.1 9.7 23.6 3.4 8.1 0.1 5.1 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) HNH_5 PF14279.6 CDJ81626.1 - 1.1 9.1 15.5 3.5 7.5 0.9 4.9 4 1 0 4 4 4 0 HNH endonuclease ADK_lid PF05191.14 CDJ81626.1 - 1.2 9.1 12.0 8.1 6.5 2.8 3.5 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-LYAR PF08790.11 CDJ81626.1 - 1.7 8.6 22.4 5.5 7.0 1.4 5.3 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger XPA_N PF01286.18 CDJ81626.1 - 2.2 8.4 15.9 18 5.5 0.1 5.0 5 0 0 5 5 5 0 XPA protein N-terminal HypA PF01155.19 CDJ81626.1 - 2.4 8.2 14.2 2.7 8.1 3.3 3.5 1 1 3 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zf_RING PF16744.5 CDJ81626.1 - 2.7 8.2 15.1 10 6.3 0.6 4.9 2 1 3 5 5 5 0 KIAA1045 RING finger HalOD2 PF18547.1 CDJ81626.1 - 3.6 7.6 6.7 2.5 8.1 0.2 3.2 4 0 0 4 4 3 0 Halobacterial output domain 2 Zn_ribbon_SprT PF17283.2 CDJ81626.1 - 4.3 7.3 18.2 0.98 9.4 4.0 3.5 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zf-C2HE PF16278.5 CDJ81626.1 - 4.3 7.9 24.0 48 4.5 0.4 4.5 1 1 2 3 3 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 CDJ81626.1 - 6.3 6.6 17.0 15 5.5 0.2 4.6 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-RING_2 PF13639.6 CDJ81629.1 - 9.1e-10 38.7 6.7 2.1e-09 37.6 6.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ81629.1 - 1.1e-07 31.6 4.6 2.1e-07 30.6 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CUE PF02845.16 CDJ81629.1 - 1.1e-07 31.4 0.0 2.5e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 CUE domain zf-C3HC4_3 PF13920.6 CDJ81629.1 - 3.8e-07 29.9 1.1 7.8e-07 28.9 1.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDJ81629.1 - 7.3e-06 26.2 5.9 1.6e-05 25.1 5.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDJ81629.1 - 4.3e-05 23.3 1.7 0.0001 22.1 1.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ81629.1 - 0.00038 20.4 1.3 0.00074 19.4 1.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 CDJ81629.1 - 0.0016 18.2 0.9 0.0044 16.7 0.9 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 CDJ81629.1 - 0.0016 18.5 1.8 0.0048 16.9 1.8 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CDJ81629.1 - 0.0073 16.3 1.8 0.016 15.2 1.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CDJ81629.1 - 0.013 15.3 2.7 0.029 14.2 2.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CDJ81629.1 - 0.32 10.8 6.9 1.9 8.3 6.9 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 CDJ81629.1 - 1 9.0 5.1 2 8.1 5.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Pox_MCEL PF03291.16 CDJ81630.1 - 7e-77 258.8 0.0 8.8e-77 258.4 0.0 1.0 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 CDJ81630.1 - 2.1e-14 54.0 0.1 6.8e-14 52.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ81630.1 - 1e-08 35.7 0.0 2.9e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ81630.1 - 8.8e-07 28.8 0.0 2.5e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ81630.1 - 5.7e-06 27.0 0.0 1.3e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ81630.1 - 0.00019 21.3 0.0 0.00041 20.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ81630.1 - 0.0081 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 CDJ81630.1 - 0.013 14.7 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family CheR PF01739.18 CDJ81630.1 - 0.1 12.1 0.0 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain LIM PF00412.22 CDJ81631.1 - 1.8e-32 111.3 13.3 2.4e-16 59.7 3.2 2.4 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 CDJ81631.1 - 9.6e-20 70.2 2.4 9.6e-20 70.2 2.4 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CDJ81631.1 - 9.5e-06 25.4 0.2 2.5e-05 24.1 0.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain Furin-like_2 PF15913.5 CDJ81631.1 - 0.009 16.2 3.5 0.009 16.2 3.5 2.2 1 1 1 2 2 2 1 Furin-like repeat, cysteine-rich E6 PF00518.17 CDJ81631.1 - 0.2 12.1 7.8 2 8.9 1.8 2.6 1 1 2 3 3 3 0 Early Protein (E6) TNFR_c6 PF00020.18 CDJ81631.1 - 1.7 9.1 11.7 7.6 7.0 0.4 3.3 3 0 0 3 3 3 0 TNFR/NGFR cysteine-rich region C1_1 PF00130.22 CDJ81631.1 - 2.2 8.2 13.1 1.7 8.6 3.5 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Flu_B_M2 PF04772.12 CDJ81632.1 - 0.0026 18.0 0.2 0.071 13.4 0.0 2.4 2 0 0 2 2 2 1 Influenza B matrix protein 2 (BM2) G0-G1_switch_2 PF15103.6 CDJ81632.1 - 0.14 12.6 2.1 8.7 6.8 0.9 2.6 2 0 0 2 2 2 0 G0/G1 switch protein 2 GWT1 PF06423.12 CDJ81632.1 - 5.1 7.2 6.7 11 6.1 5.3 2.3 1 1 0 1 1 1 0 GWT1 DUF2070 PF09843.9 CDJ81632.1 - 7.3 4.7 11.2 10 4.3 11.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4834 PF16118.5 CDJ81633.1 - 3.9 8.5 8.2 1.8 9.6 3.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Glycoprot_B_PH2 PF17417.2 CDJ81634.1 - 0.06 13.7 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B PH-like domain Glyoxalase PF00903.25 CDJ81636.1 - 1.1e-22 80.6 0.0 1.2e-22 80.4 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CDJ81636.1 - 3.9e-07 30.3 0.0 1.1e-06 28.8 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 CDJ81636.1 - 6.1e-05 23.8 0.0 0.00013 22.7 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 CDJ81636.1 - 0.0034 17.3 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 1 Glyoxalase-like domain TxDE PF18711.1 CDJ81636.1 - 0.069 13.3 0.0 0.33 11.1 0.0 2.0 2 0 0 2 2 2 0 Toxoflavin-degrading enzyme Glyoxalase_3 PF13468.6 CDJ81636.1 - 0.072 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain Aldedh PF00171.22 CDJ81637.1 - 1.6e-186 620.3 0.0 1.8e-186 620.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 CDJ81638.1 - 1.2e-05 24.1 0.3 1.5e-05 23.7 0.3 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 CDJ81639.1 - 1.4e-159 531.5 0.0 1.7e-159 531.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 CDJ81640.1 - 1e-100 337.5 0.0 1.4e-100 337.0 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ly-6_related PF06579.12 CDJ81641.1 - 5.1e-30 104.3 0.9 6.1e-30 104.0 0.9 1.1 1 0 0 1 1 1 1 Caenorhabditis elegans ly-6-related protein PAXNEB PF05625.11 CDJ81641.1 - 0.18 10.9 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 PAXNEB protein Col_cuticle_N PF01484.17 CDJ81642.1 - 1.6e-21 76.1 0.2 2e-21 75.8 0.2 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ81642.1 - 6.4e-13 48.3 143.9 7.8e-08 32.0 41.8 4.2 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) COX14 PF14880.6 CDJ81642.1 - 0.005 16.7 3.1 0.0078 16.0 3.1 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c assembly RRM_1 PF00076.22 CDJ81643.1 - 3.9e-25 87.5 0.0 3.2e-11 42.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.13 CDJ81643.1 - 6.5e-14 52.1 0.0 1e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 SPOC domain RRM_3 PF08777.11 CDJ81643.1 - 2.3e-09 37.2 0.1 0.0013 18.7 0.0 3.9 3 1 0 3 3 3 3 RNA binding motif RRM_7 PF16367.5 CDJ81643.1 - 8.2e-06 25.9 0.0 0.0023 18.0 0.0 2.8 2 1 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 CDJ81643.1 - 0.0015 18.5 0.2 0.14 12.2 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CDJ81643.1 - 0.035 14.0 0.0 1.9 8.4 0.0 2.6 2 0 0 2 2 2 0 Occluded RNA-recognition motif ATP_bind_3 PF01171.20 CDJ81644.1 - 1.4e-16 60.7 0.0 2.5e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 CDJ81644.1 - 3.2e-16 58.5 3.3 3.2e-16 58.5 3.3 2.4 2 0 0 2 2 2 1 Zinc-ribbon ThiI PF02568.14 CDJ81644.1 - 0.076 12.6 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) RecR PF02132.15 CDJ81644.1 - 0.47 10.1 6.3 0.13 11.8 0.6 2.7 3 0 0 3 3 3 0 RecR protein IFRD PF05004.13 CDJ81645.1 - 6.6e-45 153.5 3.5 9.4e-45 153.0 3.5 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.12 CDJ81645.1 - 2.4e-16 60.0 1.8 6.2e-16 58.7 1.8 1.8 1 0 0 1 1 1 1 Interferon-related protein conserved region BID PF06393.11 CDJ81645.1 - 0.0088 15.6 0.2 0.017 14.7 0.2 1.4 1 0 0 1 1 1 1 BH3 interacting domain (BID) JAB PF01398.21 CDJ81646.1 - 8.3e-18 64.5 0.0 1.6e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 CDJ81646.1 - 5e-11 42.8 0.1 1.7e-10 41.1 0.0 1.8 2 0 0 2 2 2 1 USP8 dimerisation domain Prok-JAB PF14464.6 CDJ81646.1 - 4.8e-05 23.1 0.1 0.00014 21.7 0.1 1.8 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Rad4 PF03835.15 CDJ81647.1 - 4.4e-22 78.4 1.5 4.4e-22 78.4 1.5 4.3 6 0 0 6 6 6 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 CDJ81647.1 - 9.5e-20 70.8 0.0 2.2e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 CDJ81647.1 - 2.6e-15 56.0 0.1 1.1e-14 53.9 0.1 2.2 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 CDJ81647.1 - 3.5e-07 31.1 2.9 3.5e-07 31.1 2.9 6.7 5 2 1 6 6 6 1 Rad4 beta-hairpin domain 2 DUF5539 PF17693.1 CDJ81647.1 - 5.4 6.6 11.1 15 5.2 9.7 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5539) DUF4452 PF14618.6 CDJ81649.1 - 0.048 13.5 1.1 0.074 12.9 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) DUF4988 PF16378.5 CDJ81649.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function wnt PF00110.19 CDJ81650.1 - 7.6e-107 357.5 24.9 8.7e-107 357.3 24.9 1.0 1 0 0 1 1 1 1 wnt family E1-E2_ATPase PF00122.20 CDJ81652.1 - 7.7e-43 146.1 0.1 2.1e-42 144.7 0.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CDJ81652.1 - 6.8e-22 78.8 0.3 1.6e-12 48.2 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 CDJ81652.1 - 3.5e-13 49.7 3.3 5.1e-13 49.2 0.6 2.7 2 1 0 2 2 2 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.26 CDJ81652.1 - 7.5e-05 22.3 0.0 0.00016 21.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CDJ81652.1 - 0.00014 21.9 0.0 0.00033 20.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Aa_trans PF01490.18 CDJ81653.1 - 5e-64 216.5 23.0 7.4e-64 215.9 23.0 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RAMP4 PF06624.12 CDJ81653.1 - 0.094 12.8 0.9 0.28 11.3 0.9 1.8 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 Astacin PF01400.24 CDJ81654.1 - 7.7e-58 195.3 1.2 1.1e-57 194.8 1.2 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) THB PF18362.1 CDJ81654.1 - 0.012 15.2 0.0 0.22 11.2 0.0 2.5 2 0 0 2 2 2 0 Tri-helix bundle domain Peptidase_M10 PF00413.24 CDJ81654.1 - 0.29 10.9 2.0 5.8 6.7 0.8 2.3 1 1 0 2 2 2 0 Matrixin RRM_1 PF00076.22 CDJ81656.1 - 3.2e-40 135.8 0.1 2.2e-14 53.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ81656.1 - 1.7e-05 24.8 0.0 0.079 13.1 0.0 3.6 3 0 0 3 3 3 1 RNA recognition motif RNA_bind PF08675.11 CDJ81656.1 - 0.0043 17.0 0.1 12 6.0 0.0 3.8 3 1 0 3 3 3 2 RNA binding domain 120_Rick_ant PF12574.8 CDJ81656.1 - 0.09 12.0 0.2 3.1 6.9 0.1 2.2 2 0 0 2 2 2 0 120 KDa Rickettsia surface antigen TFIIA PF03153.13 CDJ81656.1 - 3.6 7.5 14.2 5.3 6.9 14.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sad1_UNC PF07738.13 CDJ81657.1 - 4.5e-33 114.1 0.0 7.7e-33 113.3 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CDC45 PF02724.14 CDJ81657.1 - 0.28 9.4 4.1 0.49 8.6 4.1 1.3 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 CDJ81657.1 - 0.33 11.3 8.3 2 8.9 1.0 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cyto_heme_lyase PF01265.17 CDJ81658.1 - 0.063 12.9 0.3 0.068 12.7 0.3 1.1 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase FAM167 PF11652.8 CDJ81659.1 - 0.085 13.3 0.0 0.11 13.0 0.0 1.5 1 1 0 1 1 1 0 FAM167 Zona_pellucida PF00100.23 CDJ81662.1 - 5.9e-06 26.3 0.4 7.4e-06 25.9 0.4 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Mito_carr PF00153.27 CDJ81663.1 - 1.1e-59 198.3 0.7 3e-21 75.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HSP20 PF00011.21 CDJ81664.1 - 5.3e-24 84.3 0.1 7.2e-24 83.9 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ81664.1 - 4.5e-06 26.1 0.0 6.5e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Acyltransferase PF01553.21 CDJ81665.1 - 4.6e-22 78.1 0.0 8e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF411 PF04214.13 CDJ81665.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF IF-2B PF01008.17 CDJ81666.1 - 1e-55 188.9 0.4 1.4e-54 185.3 0.0 2.0 2 0 0 2 2 2 1 Initiation factor 2 subunit family DUF1759 PF03564.15 CDJ81666.1 - 8e-05 22.6 0.7 0.00023 21.1 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) AAA_33 PF13671.6 CDJ81666.1 - 0.065 13.4 0.1 1.2 9.3 0.1 2.5 1 1 0 1 1 1 0 AAA domain HAP2-GCS1 PF10699.9 CDJ81666.1 - 0.11 12.5 0.0 0.72 9.9 0.0 2.1 1 1 0 1 1 1 0 Male gamete fusion factor BTB PF00651.31 CDJ81669.1 - 0.007 16.6 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain RPA_C PF08784.11 CDJ81670.1 - 1.8e-07 31.8 0.2 4.3e-07 30.5 0.2 1.6 1 0 0 1 1 1 1 Replication protein A C terminal U3snoRNP10 PF12397.8 CDJ81671.1 - 1.9e-16 60.5 5.1 5.2e-16 59.0 4.4 2.3 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 10 ODC_AZ PF02100.17 CDJ81671.1 - 0.12 12.3 0.3 0.54 10.2 0.1 2.2 2 0 0 2 2 2 0 Ornithine decarboxylase antizyme ABC2_membrane PF01061.24 CDJ81672.1 - 1.7e-37 128.9 12.7 3.1e-37 128.1 12.7 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CDJ81672.1 - 3.5e-18 66.4 0.1 5.3e-18 65.8 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CDJ81672.1 - 0.0003 20.7 0.0 0.34 10.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CDJ81672.1 - 0.00035 20.5 0.3 0.00074 19.5 0.3 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_28 PF13521.6 CDJ81672.1 - 0.00087 19.6 0.0 0.0034 17.7 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ81672.1 - 0.00089 19.7 0.1 0.0017 18.7 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDJ81672.1 - 0.0016 18.7 0.0 0.0049 17.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 CDJ81672.1 - 0.0091 15.5 0.0 0.032 13.7 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 CDJ81672.1 - 0.012 14.7 0.2 0.021 13.9 0.2 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 CDJ81672.1 - 0.015 14.9 0.3 0.035 13.7 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CDJ81672.1 - 0.021 15.4 0.1 0.04 14.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 CDJ81672.1 - 0.024 13.8 10.3 0.043 12.9 10.3 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_33 PF13671.6 CDJ81672.1 - 0.032 14.4 0.1 0.057 13.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CDJ81672.1 - 0.041 13.6 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 CDJ81672.1 - 0.051 12.9 0.3 0.086 12.1 0.3 1.2 1 0 0 1 1 1 0 Septin cobW PF02492.19 CDJ81672.1 - 0.053 13.1 1.0 0.09 12.4 1.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 CDJ81672.1 - 0.057 13.5 0.6 0.13 12.4 0.6 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 CDJ81672.1 - 0.06 12.7 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_ATPase PF09818.9 CDJ81672.1 - 0.06 12.1 0.1 0.095 11.5 0.1 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_29 PF13555.6 CDJ81672.1 - 0.069 12.9 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 CDJ81672.1 - 0.084 13.2 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 CDJ81672.1 - 0.15 11.9 0.2 0.28 11.1 0.2 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.6 CDJ81672.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CDJ81672.1 - 0.18 11.8 0.9 0.4 10.7 0.2 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE 7tm_1 PF00001.21 CDJ81673.1 - 3.6e-35 121.6 21.7 9.5e-35 120.2 21.0 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ81673.1 - 9.5e-06 25.2 22.7 0.00024 20.6 22.7 2.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 CDJ81673.1 - 0.00039 20.2 20.8 0.0014 18.4 20.6 2.0 1 1 1 2 2 2 1 Olfactory receptor Astacin PF01400.24 CDJ81674.1 - 1.2e-53 181.6 0.0 1.3e-53 181.5 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 CDJ81674.1 - 0.00017 21.3 0.1 0.00022 20.9 0.1 1.3 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CDJ81674.1 - 0.00042 20.2 0.2 0.00094 19.1 0.3 1.7 1 1 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 CDJ81674.1 - 0.0011 18.0 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.6 CDJ81674.1 - 0.026 15.1 0.1 0.047 14.2 0.0 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CDJ81674.1 - 0.036 14.2 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M57 PF12388.8 CDJ81674.1 - 0.036 13.7 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_2 PF13574.6 CDJ81674.1 - 0.1 12.5 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Zn_peptidase_2 PF04298.12 CDJ81674.1 - 0.25 10.7 0.1 0.39 10.1 0.1 1.2 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Lectin_C PF00059.21 CDJ81675.1 - 4.4e-18 66.0 0.2 8.8e-18 65.0 0.1 1.6 2 0 0 2 2 2 1 Lectin C-type domain Filament PF00038.21 CDJ81675.1 - 0.0054 16.3 0.2 0.01 15.5 0.2 1.4 1 0 0 1 1 1 1 Intermediate filament protein GLE1 PF07817.13 CDJ81675.1 - 0.052 12.7 0.1 0.28 10.4 0.1 1.8 1 1 0 2 2 2 0 GLE1-like protein GlcNAc-1_reg PF18440.1 CDJ81675.1 - 0.15 12.3 0.2 0.25 11.6 0.2 1.3 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain BBP1_C PF15272.6 CDJ81675.1 - 0.16 11.8 5.5 0.33 10.7 5.5 1.5 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal RWD PF05773.22 CDJ81676.1 - 3.1e-11 43.6 0.3 6e-11 42.7 0.3 1.5 1 0 0 1 1 1 1 RWD domain IBR PF01485.21 CDJ81676.1 - 1.5e-08 34.7 40.3 1.9e-05 24.8 4.7 4.4 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 CDJ81676.1 - 8.3e-06 25.7 6.4 8.3e-06 25.7 6.4 3.6 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDJ81676.1 - 1.1e-05 25.1 4.9 1.1e-05 25.1 4.9 4.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ81676.1 - 2.4e-05 24.6 6.1 2.4e-05 24.6 6.1 4.2 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 CDJ81676.1 - 0.00023 21.0 5.4 0.00023 21.0 5.4 4.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ81676.1 - 0.00055 19.8 10.5 0.00055 19.8 10.5 4.5 5 0 0 5 5 5 1 zinc-RING finger domain zf-RING_11 PF17123.5 CDJ81676.1 - 4.6 7.1 14.3 0.15 11.8 7.3 2.4 2 0 0 2 2 2 0 RING-like zinc finger IBR PF01485.21 CDJ81677.1 - 2.9e-17 62.6 39.7 1.7e-10 40.9 2.4 3.9 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 CDJ81677.1 - 5e-12 46.1 0.0 1e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-C3HC4 PF00097.25 CDJ81677.1 - 0.00013 21.8 6.8 0.00013 21.8 6.8 4.2 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ81677.1 - 0.00054 19.9 8.0 0.00054 19.9 8.0 3.7 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDJ81677.1 - 0.00085 19.2 10.4 0.00085 19.2 10.4 3.9 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CDJ81677.1 - 0.0019 18.0 5.5 0.0019 18.0 5.5 4.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ81677.1 - 0.002 18.4 9.7 0.002 18.4 9.7 4.8 4 1 1 5 5 5 1 Ring finger domain zf-C3HC4_4 PF15227.6 CDJ81677.1 - 0.017 15.3 2.6 0.017 15.3 2.6 5.1 5 1 0 5 5 5 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 CDJ81677.1 - 0.018 14.8 10.6 0.04 13.7 9.0 2.6 2 0 0 2 2 2 0 RING-like zinc finger IBR PF01485.21 CDJ81678.1 - 3.1e-16 59.3 25.6 5.4e-11 42.6 2.4 3.4 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain RWD PF05773.22 CDJ81678.1 - 6.6e-13 49.0 0.2 1.4e-12 47.9 0.2 1.6 1 0 0 1 1 1 1 RWD domain Neprosin_AP PF14365.6 CDJ81678.1 - 0.021 15.3 0.0 0.038 14.5 0.0 1.4 1 0 0 1 1 1 0 Neprosin activation peptide Papo_T_antigen PF02380.15 CDJ81678.1 - 0.024 14.8 1.5 0.024 14.8 1.5 2.9 3 0 0 3 3 3 0 T-antigen specific domain RWD PF05773.22 CDJ81679.1 - 3.2e-09 37.1 0.2 5.7e-09 36.3 0.2 1.4 1 0 0 1 1 1 1 RWD domain IBR PF01485.21 CDJ81679.1 - 1.2e-07 31.8 21.3 1.5e-06 28.3 6.2 2.3 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain NodZ PF05830.11 CDJ81679.1 - 0.085 11.7 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) zinc_ribbon_2 PF13240.6 CDJ81679.1 - 0.48 10.2 0.1 0.48 10.2 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon domain WD40 PF00400.32 CDJ81680.1 - 8.7e-14 51.7 3.9 0.002 18.9 0.3 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat ubiquitin PF00240.23 CDJ81680.1 - 2.9e-10 39.8 0.0 5.6e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family ANAPC4_WD40 PF12894.7 CDJ81680.1 - 4.6e-05 23.6 0.0 0.00054 20.2 0.0 2.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Ubiquitin_2 PF14560.6 CDJ81680.1 - 0.02 15.3 0.0 0.065 13.7 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain eIF2A PF08662.11 CDJ81680.1 - 0.071 13.0 0.0 0.45 10.4 0.0 1.9 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Rad60-SLD_2 PF13881.6 CDJ81680.1 - 0.16 12.0 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DB PF01682.19 CDJ81681.1 - 2.3e-12 47.0 2.3 2.3e-12 47.0 2.3 1.9 3 0 0 3 3 3 1 DB module DUF5478 PF17572.2 CDJ81681.1 - 0.045 13.8 0.9 0.085 13.0 0.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5478) DB PF01682.19 CDJ81682.1 - 1e-23 83.4 10.9 1e-23 83.4 10.9 1.5 2 0 0 2 2 2 1 DB module UPRTase PF14681.6 CDJ81683.1 - 3.1e-24 85.6 0.0 3.3e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase BTD PF09270.10 CDJ81684.1 - 5.3e-73 244.3 0.0 8.4e-73 243.7 0.0 1.3 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.11 CDJ81684.1 - 3.4e-59 199.8 0.8 1.7e-51 174.8 0.1 2.3 2 0 0 2 2 2 2 LAG1, DNA binding TIG PF01833.24 CDJ81684.1 - 6e-06 26.2 0.0 1.7e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 IPT/TIG domain NAD_binding_8 PF13450.6 CDJ81685.1 - 6.9e-11 42.2 0.4 2.3e-10 40.6 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 CDJ81685.1 - 2.1e-10 40.5 0.7 7e-05 22.3 0.0 2.8 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase DAO PF01266.24 CDJ81685.1 - 3.7e-09 36.6 3.3 3e-06 27.1 3.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CDJ81685.1 - 1.6e-08 34.4 1.3 2.5e-08 33.7 0.7 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CDJ81685.1 - 3.6e-07 29.6 8.0 1.5e-05 24.3 4.2 2.6 3 0 0 3 3 3 2 FAD binding domain Thi4 PF01946.17 CDJ81685.1 - 2.1e-06 27.1 0.3 4.1e-06 26.2 0.3 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 CDJ81685.1 - 1.2e-05 24.7 0.0 5.8e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CDJ81685.1 - 2e-05 24.1 1.1 5.2e-05 22.7 0.6 1.8 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 CDJ81685.1 - 7.6e-05 22.0 3.9 0.0012 18.1 2.7 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 CDJ81685.1 - 0.00017 22.1 2.2 0.0078 16.7 1.5 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ81685.1 - 0.00029 19.6 1.4 0.00068 18.5 0.6 1.8 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 CDJ81685.1 - 0.00099 18.1 1.3 0.0081 15.1 0.3 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 CDJ81685.1 - 0.06 12.6 0.4 0.14 11.4 0.4 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 CDJ81685.1 - 0.064 12.0 0.2 0.1 11.4 0.2 1.2 1 0 0 1 1 1 0 MCRA family GDI PF00996.18 CDJ81685.1 - 0.071 11.6 0.0 5.9 5.3 0.0 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor Lycopene_cycl PF05834.12 CDJ81685.1 - 0.086 11.9 0.8 0.17 10.9 0.8 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 CDJ81685.1 - 0.17 11.2 0.2 0.31 10.3 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CAP PF00188.26 CDJ81686.1 - 0.0029 18.4 0.0 0.0086 16.9 0.0 1.7 1 1 0 1 1 1 1 Cysteine-rich secretory protein family RPAP1_N PF08621.10 CDJ81687.1 - 7.2e-08 32.1 0.9 1.9e-07 30.7 0.9 1.7 1 0 0 1 1 1 1 RPAP1-like, N-terminal DUF3835 PF12927.7 CDJ81687.1 - 0.43 11.5 3.5 0.46 11.4 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3835) SAYSvFN PF10260.9 CDJ81688.1 - 6.4e-26 90.1 0.3 1e-25 89.4 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) DUF1673 PF07895.11 CDJ81688.1 - 0.059 13.1 0.1 0.15 11.8 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) HEAT PF02985.22 CDJ81689.1 - 0.11 12.9 0.3 0.11 12.9 0.3 4.8 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.6 CDJ81689.1 - 0.17 12.4 5.0 7.6 7.2 0.2 3.1 2 0 0 2 2 2 0 HEAT-like repeat Nore1-SARAH PF16517.5 CDJ81690.1 - 0.12 12.3 0.4 0.3 11.0 0.4 1.7 1 0 0 1 1 1 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Peptidase_M49 PF03571.15 CDJ81691.1 - 9e-226 750.5 0.1 1.1e-225 750.3 0.1 1.0 1 0 0 1 1 1 1 Peptidase family M49 aGPT-Pplase2 PF18724.1 CDJ81691.1 - 0.051 13.3 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 2 DUF1700 PF08006.11 CDJ81691.1 - 0.073 12.6 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) JmjN PF02375.17 CDJ81691.1 - 0.66 10.0 4.8 26 4.9 0.4 3.9 4 0 0 4 4 4 0 jmjN domain Aminotran_3 PF00202.21 CDJ81693.1 - 3.8e-53 180.6 0.3 4.7e-53 180.3 0.3 1.0 1 0 0 1 1 1 1 Aminotransferase class-III RD3 PF14473.6 CDJ81694.1 - 3.6e-24 85.1 2.3 4.8e-24 84.7 2.3 1.1 1 0 0 1 1 1 1 RD3 protein DnaJ PF00226.31 CDJ81695.1 - 3.9e-25 87.8 2.1 5.8e-25 87.2 2.1 1.3 1 0 0 1 1 1 1 DnaJ domain Corona_S2 PF01601.16 CDJ81695.1 - 4.4e-05 22.2 3.0 5.2e-05 21.9 3.0 1.0 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein PQQ_3 PF13570.6 CDJ81697.1 - 0.24 12.0 2.0 15 6.3 0.1 2.6 2 0 0 2 2 2 0 PQQ-like domain Fibrinogen_C PF00147.18 CDJ81701.1 - 3.5e-36 125.1 4.7 3.5e-36 125.1 4.7 1.5 2 0 0 2 2 2 1 Fibrinogen beta and gamma chains, C-terminal globular domain Lectin_C PF00059.21 CDJ81701.1 - 4.8e-08 33.7 9.5 4.8e-08 33.7 9.5 2.5 3 0 0 3 3 3 1 Lectin C-type domain Myosin_head PF00063.21 CDJ81702.1 - 2.9e-211 703.3 20.5 4.3e-182 606.9 10.2 2.6 3 0 0 3 3 3 2 Myosin head (motor domain) IQ PF00612.27 CDJ81702.1 - 4.7e-08 32.1 17.6 0.014 15.2 0.4 4.9 4 0 0 4 4 4 4 IQ calmodulin-binding motif C1_1 PF00130.22 CDJ81702.1 - 2.3e-06 27.4 13.3 5e-06 26.3 13.3 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RA PF00788.23 CDJ81702.1 - 3.8e-05 24.2 0.0 0.00014 22.5 0.0 2.1 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain C1_2 PF03107.16 CDJ81702.1 - 0.00053 20.2 9.0 0.0011 19.2 9.0 1.5 1 0 0 1 1 1 1 C1 domain AAA_16 PF13191.6 CDJ81702.1 - 0.0056 17.1 0.0 0.019 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDJ81702.1 - 0.0084 16.4 0.2 0.085 13.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 CDJ81702.1 - 0.044 14.1 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDJ81702.1 - 0.046 14.2 1.0 0.19 12.3 0.1 2.4 2 1 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 CDJ81702.1 - 0.1 13.0 0.1 0.35 11.3 0.1 1.9 1 0 0 1 1 1 0 RNA helicase zf-RING_9 PF13901.6 CDJ81702.1 - 0.16 12.0 10.2 0.35 10.8 9.0 2.2 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon FYVE_2 PF02318.16 CDJ81702.1 - 1 9.6 6.8 2.1 8.6 3.1 3.0 2 0 0 2 2 2 0 FYVE-type zinc finger PHD PF00628.29 CDJ81702.1 - 1.3 9.0 7.7 2.9 7.9 7.7 1.6 1 0 0 1 1 1 0 PHD-finger PHD_2 PF13831.6 CDJ81702.1 - 1.7 8.3 4.9 3.9 7.1 4.9 1.5 1 0 0 1 1 1 0 PHD-finger Plectin PF00681.20 CDJ81703.1 - 6.9e-71 233.9 18.5 0.0038 17.1 0.0 33.9 29 6 7 36 36 36 22 Plectin repeat Spectrin PF00435.21 CDJ81703.1 - 7e-68 225.8 156.0 1.2e-07 32.1 2.8 25.1 20 3 5 25 25 25 18 Spectrin repeat pXO2-34 PF17362.2 CDJ81703.1 - 0.0029 17.4 0.6 11 5.9 0.1 3.9 3 0 0 3 3 3 2 Family of unknown function DUF4777 PF16007.5 CDJ81703.1 - 0.047 13.9 0.0 18 5.7 0.0 4.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4777) CH PF00307.31 CDJ81704.1 - 8.6e-25 87.0 0.0 1.4e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CDJ81704.1 - 8.5e-07 28.7 0.0 1.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain MitMem_reg PF13012.6 CDJ81704.1 - 0.035 14.5 0.0 1.2 9.6 0.0 2.5 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function cNMP_binding PF00027.29 CDJ81705.1 - 8.7e-19 67.4 0.0 1.6e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 CDJ81705.1 - 1.5e-17 63.7 14.0 2e-17 63.3 14.0 1.1 1 0 0 1 1 1 1 Ion transport protein DUF3048_C PF17479.2 CDJ81705.1 - 0.11 12.9 0.2 0.21 12.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3048) C-terminal domain DHHC PF01529.20 CDJ81705.1 - 1.8 8.7 9.1 0.17 12.0 1.5 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase PPI_Ypi1 PF07491.11 CDJ81706.1 - 1.7e-20 72.6 6.2 1.7e-20 72.6 6.2 1.6 2 0 0 2 2 2 1 Protein phosphatase inhibitor Scramblase PF03803.15 CDJ81706.1 - 0.058 12.7 0.1 0.067 12.5 0.1 1.0 1 0 0 1 1 1 0 Scramblase Ku_N PF03731.15 CDJ81707.1 - 2.4e-16 60.2 0.1 3e-16 59.8 0.1 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 CDJ81707.1 - 0.001 19.4 0.8 0.0018 18.6 0.8 1.3 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CDJ81707.1 - 0.0043 17.7 0.3 0.018 15.7 0.2 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain Ku PF02735.16 CDJ81708.1 - 7.9e-33 113.9 0.3 1.9e-32 112.6 0.3 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain EF-hand_1 PF00036.32 CDJ81708.1 - 2e-11 42.6 1.1 0.0052 16.2 0.5 4.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CDJ81708.1 - 5.7e-10 38.3 0.9 0.097 12.7 0.0 4.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 CDJ81708.1 - 4.9e-09 36.5 4.8 0.0039 17.6 0.2 4.5 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_8 PF13833.6 CDJ81708.1 - 5.4e-05 23.0 1.4 0.15 11.9 0.2 3.5 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ81708.1 - 0.00053 19.4 0.7 1.4 8.6 0.0 3.4 3 0 0 3 3 3 2 EF hand Ku_PK_bind PF08785.11 CDJ81708.1 - 0.0012 19.0 0.0 0.0046 17.1 0.0 2.1 1 1 0 1 1 1 1 Ku C terminal domain like SPARC_Ca_bdg PF10591.9 CDJ81708.1 - 0.0028 17.9 0.2 0.023 15.0 0.1 2.5 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region GRIM-19 PF06212.12 CDJ81711.1 - 7.9e-50 168.2 0.0 1.1e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 GRIM-19 protein TPR_2 PF07719.17 CDJ81712.1 - 6.4e-09 35.2 7.7 0.0015 18.5 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ81712.1 - 3.8e-06 27.1 1.2 6.4e-06 26.4 0.4 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ81712.1 - 4.1e-06 26.4 5.5 0.024 14.5 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ81712.1 - 0.00015 21.5 2.6 0.14 12.2 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ81712.1 - 0.00017 22.1 1.2 0.84 10.6 0.6 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat RecG_N PF17190.4 CDJ81712.1 - 0.003 18.2 4.4 0.0067 17.1 4.1 1.7 1 1 0 1 1 1 1 RecG N-terminal helical domain TPR_11 PF13414.6 CDJ81712.1 - 0.0041 16.8 6.1 0.025 14.3 0.1 2.9 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.6 CDJ81712.1 - 0.017 15.7 3.2 1.7 9.4 1.7 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.7 CDJ81712.1 - 0.049 13.7 0.7 0.14 12.3 0.7 1.9 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) Noelin-1 PF12308.8 CDJ81712.1 - 0.053 13.5 0.1 0.083 12.9 0.1 1.3 1 0 0 1 1 1 0 Neurogenesis glycoprotein TPR_17 PF13431.6 CDJ81712.1 - 0.081 13.3 0.6 3.3 8.3 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ81712.1 - 0.14 12.0 3.5 5.2 7.1 0.4 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat MukB PF04310.12 CDJ81712.1 - 0.17 11.7 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 MukB N-terminal HemY_N PF07219.13 CDJ81712.1 - 0.29 11.3 1.8 0.75 10.0 1.8 1.8 1 1 0 1 1 1 0 HemY protein N-terminus TPR_6 PF13174.6 CDJ81712.1 - 0.42 11.3 4.0 27 5.7 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat CDC37_C PF08564.10 CDJ81712.1 - 1.9 8.7 6.1 0.44 10.7 0.1 2.5 2 1 0 2 2 2 0 Cdc37 C terminal domain UPF0242 PF06785.11 CDJ81712.1 - 3.2 7.8 7.5 4.4 7.4 7.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Lon_C PF05362.13 CDJ81713.1 - 1.3e-71 240.3 0.0 2.7e-71 239.3 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 CDJ81713.1 - 4.3e-33 115.0 1.8 4.3e-33 115.0 1.8 1.6 2 0 0 2 2 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 CDJ81713.1 - 4e-23 82.3 0.0 1.1e-22 80.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDJ81713.1 - 5.8e-09 36.1 0.0 1.3e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 CDJ81713.1 - 9.8e-08 31.9 0.1 2.1e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 CDJ81713.1 - 1.6e-06 28.6 0.0 1.2e-05 25.8 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 CDJ81713.1 - 8.2e-06 26.0 0.0 2.4e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 CDJ81713.1 - 2.1e-05 23.6 0.3 0.00016 20.7 0.0 2.1 2 0 0 2 2 2 1 PrkA AAA domain AAA_22 PF13401.6 CDJ81713.1 - 3.3e-05 24.2 0.6 0.00075 19.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 CDJ81713.1 - 0.0003 20.1 0.0 0.0003 20.1 0.0 1.6 2 0 0 2 2 1 1 TIP49 P-loop domain AAA_28 PF13521.6 CDJ81713.1 - 0.00049 20.4 1.1 0.6 10.3 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 CDJ81713.1 - 0.0016 18.2 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CDJ81713.1 - 0.0024 17.6 0.0 0.008 15.9 0.0 1.9 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CDJ81713.1 - 0.0026 17.5 0.0 0.0064 16.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 CDJ81713.1 - 0.0037 17.3 0.1 0.028 14.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Torsin PF06309.11 CDJ81713.1 - 0.0061 16.7 0.2 0.017 15.2 0.0 1.8 2 0 0 2 2 1 1 Torsin RNA_helicase PF00910.22 CDJ81713.1 - 0.0074 16.7 0.0 0.018 15.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase Cytidylate_kin PF02224.18 CDJ81713.1 - 0.0088 15.8 0.3 0.037 13.7 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase AAA_18 PF13238.6 CDJ81713.1 - 0.0091 16.5 1.6 0.021 15.4 0.0 2.5 3 0 0 3 3 2 1 AAA domain TsaE PF02367.17 CDJ81713.1 - 0.012 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 CDJ81713.1 - 0.013 15.3 3.4 0.018 14.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CDJ81713.1 - 0.02 14.8 0.0 0.049 13.5 0.0 1.7 2 0 0 2 2 1 0 NACHT domain Mg_chelatase PF01078.21 CDJ81713.1 - 0.024 14.0 0.1 0.072 12.5 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CPT PF07931.12 CDJ81713.1 - 0.026 14.4 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NTPase_1 PF03266.15 CDJ81713.1 - 0.028 14.3 0.2 0.29 11.0 0.0 2.8 2 1 1 3 3 3 0 NTPase AAA_33 PF13671.6 CDJ81713.1 - 0.031 14.4 0.0 0.081 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CDJ81713.1 - 0.049 12.7 0.1 0.17 10.9 0.0 1.9 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 CDJ81713.1 - 0.054 13.8 2.8 0.12 12.7 0.1 2.8 3 1 1 4 4 3 0 AAA domain AAA_3 PF07726.11 CDJ81713.1 - 0.059 13.2 0.0 0.19 11.6 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CDJ81713.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 CDJ81713.1 - 0.34 11.4 10.5 1.3 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CDJ81713.1 - 1 9.3 0.0 1 9.3 0.0 3.1 4 0 0 4 4 3 0 RsgA GTPase SPC12 PF06645.13 CDJ81714.1 - 3.9e-27 94.1 0.7 4.6e-27 93.9 0.7 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF2178 PF09946.9 CDJ81714.1 - 0.043 14.0 0.7 0.067 13.4 0.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) Katanin_con80 PF13925.6 CDJ81715.1 - 1.6e-08 34.8 0.2 3.2e-08 33.8 0.2 1.4 1 0 0 1 1 1 1 con80 domain of Katanin WD40 PF00400.32 CDJ81715.1 - 3.6e-07 30.8 3.2 1.2 10.2 0.0 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ81715.1 - 0.002 18.4 0.0 2.4 8.5 0.0 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain ANAPC1 PF12859.7 CDJ81715.1 - 7.3 7.2 7.1 14 6.2 2.6 3.0 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 1 tRNA-synt_1b PF00579.25 CDJ81716.1 - 1.8e-63 214.6 0.0 4e-43 147.8 0.1 3.3 2 1 0 2 2 2 2 tRNA synthetases class I (W and Y) FAM220 PF15487.6 CDJ81718.1 - 0.21 11.2 5.0 0.33 10.6 5.0 1.2 1 0 0 1 1 1 0 FAM220 family Mito_carr PF00153.27 CDJ81719.1 - 5.1e-49 164.2 1.0 5.5e-18 64.7 0.0 3.8 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.16 CDJ81719.1 - 3.2e-23 82.2 26.9 3.2e-23 82.2 26.9 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Band_7 PF01145.25 CDJ81719.1 - 6.8e-20 71.8 0.1 6.8e-20 71.8 0.1 2.1 2 0 0 2 2 2 1 SPFH domain / Band 7 family DUF2870 PF11069.8 CDJ81719.1 - 3.5 8.1 7.0 6.5 7.2 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Neur_chan_LBD PF02931.23 CDJ81720.1 - 1.6e-34 119.3 0.1 2.4e-34 118.7 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ81720.1 - 1.4e-30 107.1 0.0 3e-30 106.0 0.0 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Ebola_NP PF05505.12 CDJ81720.1 - 0.19 10.0 3.2 0.26 9.5 3.2 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein PBP_N PF17093.5 CDJ81720.1 - 3.5 7.9 6.4 16 5.8 4.6 2.4 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus RT_RNaseH_2 PF17919.1 CDJ81721.1 - 0.0021 18.1 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase AP_endonuc_2 PF01261.24 CDJ81724.1 - 5.4e-27 94.6 0.0 6.6e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel LIN37 PF15306.6 CDJ81725.1 - 1.2e-07 32.0 0.0 2.1e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 LIN37 DUF2053 PF09767.9 CDJ81726.1 - 9.3e-58 194.9 5.0 9.3e-58 194.9 5.0 1.5 2 0 0 2 2 2 1 Predicted membrane protein (DUF2053) YesK PF14150.6 CDJ81726.1 - 8.1 6.7 10.8 0.22 11.7 2.7 2.3 2 0 0 2 2 2 0 YesK-like protein UCH PF00443.29 CDJ81727.1 - 1.4e-52 178.8 0.0 1.9e-52 178.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ81727.1 - 1.6e-13 51.0 2.1 8.7e-07 28.8 0.8 2.7 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 CDJ81727.1 - 5.5e-07 30.1 0.1 1.9e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 DUSP domain EF-hand_6 PF13405.6 CDJ81727.1 - 3.8e-06 26.4 0.1 0.01 15.7 0.0 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CDJ81727.1 - 6e-06 25.4 3.5 0.0047 16.4 0.1 4.7 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.6 CDJ81727.1 - 0.0013 19.1 1.7 0.014 15.8 0.2 3.1 3 0 0 3 3 3 1 EF-hand domain pair UN_NPL4 PF11543.8 CDJ81727.1 - 0.026 15.0 0.0 32 5.1 0.0 3.3 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 Peptidase_C98 PF15499.6 CDJ81727.1 - 0.032 13.7 1.0 2.4 7.5 0.0 2.8 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase EF-hand_5 PF13202.6 CDJ81727.1 - 0.81 9.3 2.3 4.1 7.1 0.3 3.0 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.6 CDJ81727.1 - 7.3 6.5 5.4 9.8 6.1 0.2 3.5 2 1 1 3 3 3 0 EF-hand domain pair RVT_1 PF00078.27 CDJ81728.1 - 2.4e-15 56.6 0.0 5.6e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Prefoldin_2 PF01920.20 CDJ81728.1 - 0.35 10.9 13.8 2.3 8.2 2.5 3.4 3 0 0 3 3 3 0 Prefoldin subunit DUF4201 PF13870.6 CDJ81728.1 - 0.52 10.0 17.1 0.33 10.7 1.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) Med28 PF11594.8 CDJ81728.1 - 3.1 7.9 7.2 5.2 7.1 0.1 3.8 4 1 1 5 5 5 0 Mediator complex subunit 28 TPR_MLP1_2 PF07926.12 CDJ81728.1 - 3.6 7.7 19.0 1.9 8.5 0.6 4.2 4 0 0 4 4 4 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 CDJ81728.1 - 4.8 7.2 26.9 1.4 8.9 4.1 3.6 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Patched PF02460.18 CDJ81729.1 - 5e-43 147.3 19.8 6.1e-43 147.0 19.8 1.1 1 0 0 1 1 1 1 Patched family SecD_SecF PF02355.16 CDJ81729.1 - 0.0016 17.8 17.5 0.02 14.3 8.9 2.3 2 0 0 2 2 2 2 Protein export membrane protein DUF3278 PF11683.8 CDJ81729.1 - 1 9.4 7.4 0.28 11.3 1.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3278) Fumarate_red_D PF02313.17 CDJ81729.1 - 4.6 7.4 11.3 12 6.1 4.3 2.1 1 1 0 2 2 2 0 Fumarate reductase subunit D Cullin PF00888.22 CDJ81730.1 - 5.2e-179 596.8 12.3 5.2e-179 596.8 12.3 1.6 2 0 0 2 2 2 1 Cullin family Glyco_transf_25 PF01755.17 CDJ81730.1 - 3e-27 95.8 0.0 3.7e-26 92.2 0.0 2.8 2 1 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Cullin_Nedd8 PF10557.9 CDJ81730.1 - 3.8e-27 94.1 4.3 1e-26 92.7 4.3 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain Phage_TAC_12 PF12363.8 CDJ81730.1 - 0.054 13.9 0.3 0.34 11.3 0.1 2.5 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC Penicillinase_R PF03965.16 CDJ81730.1 - 0.35 11.2 3.6 4.2 7.7 0.2 3.1 3 0 0 3 3 3 0 Penicillinase repressor Pkinase PF00069.25 CDJ81731.1 - 2.5e-39 135.2 0.0 3e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ81731.1 - 9.2e-26 90.7 0.0 1.1e-25 90.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ81731.1 - 2.4e-10 40.2 0.0 3.4e-08 33.2 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CDJ81731.1 - 0.00019 21.5 0.1 0.00039 20.4 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ81731.1 - 0.001 18.0 0.2 0.0017 17.2 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CDJ81731.1 - 0.011 15.0 0.1 0.022 14.1 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDJ81731.1 - 0.015 14.9 0.1 0.029 14.0 0.1 1.4 1 1 0 1 1 1 0 RIO1 family DUF1232 PF06803.12 CDJ81731.1 - 0.023 14.5 0.1 0.023 14.5 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1232) Tail_VII PF17091.5 CDJ81731.1 - 0.066 13.1 0.7 10 6.1 0.5 2.4 2 0 0 2 2 2 0 Inovirus G7P protein KH_1 PF00013.29 CDJ81732.1 - 4.3e-33 112.9 7.3 1.2e-16 60.3 0.3 2.3 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 CDJ81732.1 - 2.1e-08 33.8 2.5 0.0021 17.8 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 CDJ81732.1 - 0.00063 19.8 2.6 0.53 10.4 0.6 2.3 2 0 0 2 2 2 2 NusA-like KH domain KH_4 PF13083.6 CDJ81732.1 - 0.00081 19.2 1.5 0.14 12.1 0.9 2.3 2 0 0 2 2 2 2 KH domain Vps5 PF09325.10 CDJ81733.1 - 6.6e-20 71.7 12.4 3.5e-17 62.7 12.4 2.1 1 1 0 1 1 1 1 Vps5 C terminal like BAR PF03114.18 CDJ81733.1 - 9.5e-06 25.4 17.0 1.1e-05 25.2 17.0 1.0 1 0 0 1 1 1 1 BAR domain Ribosomal_S24e PF01282.19 CDJ81733.1 - 0.041 13.8 1.8 1 9.4 0.0 3.3 3 1 0 3 3 3 0 Ribosomal protein S24e SPG4 PF17325.2 CDJ81733.1 - 0.31 12.1 2.4 0.36 11.9 0.9 1.9 1 1 1 2 2 2 0 Stationary phase protein 4 RecG_N PF17190.4 CDJ81733.1 - 9.8 7.0 13.3 14 6.5 3.9 3.6 1 1 3 4 4 4 0 RecG N-terminal helical domain Pkinase PF00069.25 CDJ81734.1 - 2e-57 194.6 0.0 2.7e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ81734.1 - 6.8e-43 146.8 0.0 9.8e-43 146.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 CDJ81734.1 - 2.5e-19 69.2 0.7 6.8e-19 67.9 0.7 1.8 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase_fungal PF17667.1 CDJ81734.1 - 1.4e-05 24.1 0.0 2.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDJ81734.1 - 0.036 13.4 0.1 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Kinase-like CTP_transf_like PF01467.26 CDJ81735.1 - 6.2e-22 78.3 0.0 7.7e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF1462 PF07315.11 CDJ81735.1 - 0.043 14.1 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) DUF5639 PF18690.1 CDJ81735.1 - 0.063 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5639) TPR_2 PF07719.17 CDJ81736.1 - 7.1e-05 22.6 5.9 2.4 8.5 1.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ81736.1 - 0.01 16.0 1.1 0.66 10.3 0.2 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ81736.1 - 0.014 16.2 10.3 8.6 7.5 1.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ81736.1 - 0.059 13.7 1.4 2.1 8.7 0.3 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 CDJ81736.1 - 0.072 12.3 1.7 4.1 6.5 0.1 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF4498 PF14926.6 CDJ81736.1 - 0.16 11.2 0.4 1 8.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4498) TPR_1 PF00515.28 CDJ81736.1 - 1.4 8.9 4.5 18 5.4 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Asp PF00026.23 CDJ81737.1 - 2.2e-07 30.6 0.0 0.00055 19.5 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic aspartyl protease Asp PF00026.23 CDJ81738.1 - 1.2e-83 281.1 0.8 1.4e-83 280.9 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ81738.1 - 1.1e-11 45.2 5.2 6.1e-10 39.6 5.2 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ81738.1 - 2.9e-05 23.9 0.1 0.00017 21.4 0.1 2.2 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp PF00026.23 CDJ81739.1 - 1.9e-84 283.8 0.7 2.2e-84 283.6 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ81739.1 - 8.5e-12 45.7 4.8 1.9e-10 41.3 4.8 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ81739.1 - 1.5e-05 24.8 0.1 8.1e-05 22.5 0.1 2.2 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Sre PF03125.18 CDJ81740.1 - 0.068 12.3 1.4 0.082 12.0 1.4 1.1 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor Flp1_like PF16982.5 CDJ81741.1 - 0.27 10.7 5.1 0.41 10.1 5.1 1.2 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain Sec62 PF03839.16 CDJ81741.1 - 1.3 8.5 2.9 2 7.8 2.9 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4713 PF15831.5 CDJ81741.1 - 3 8.4 11.4 4.7 7.7 11.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) Shisa PF13908.6 CDJ81741.1 - 9.2 6.5 15.4 96 3.1 15.4 2.0 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator RVT_1 PF00078.27 CDJ81742.1 - 1.6e-24 86.7 0.0 1.8e-24 86.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GATA PF00320.27 CDJ81745.1 - 6.7e-14 51.2 6.9 1.6e-13 50.0 6.9 1.7 1 0 0 1 1 1 1 GATA zinc finger SNAD4 PF18750.1 CDJ81745.1 - 0.039 14.1 1.3 0.062 13.4 1.3 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 DUF4606 PF15379.6 CDJ81745.1 - 1.3 9.3 4.8 0.56 10.5 2.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4606) Elf1 PF05129.13 CDJ81745.1 - 3.2 7.8 7.2 0.41 10.7 2.5 1.8 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like F-box PF00646.33 CDJ81746.1 - 0.0029 17.4 0.6 0.0048 16.7 0.6 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 CDJ81746.1 - 0.0037 17.1 0.0 0.0043 16.9 0.0 1.1 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 CDJ81746.1 - 0.087 12.7 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 F-box-like Fringe PF02434.16 CDJ81747.1 - 3e-06 26.9 0.1 4e-06 26.4 0.1 1.4 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 CDJ81747.1 - 8.4e-06 25.7 0.0 0.082 12.7 0.0 2.1 1 1 1 2 2 2 2 Galactosyltransferase Ldh_1_N PF00056.23 CDJ81748.1 - 1.5e-45 154.8 0.2 2.5e-45 154.0 0.2 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CDJ81748.1 - 4.5e-26 91.8 1.0 2e-25 89.7 0.2 1.9 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 CDJ81748.1 - 0.029 13.9 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase Ldh_1_N PF00056.23 CDJ81749.1 - 2.5e-44 150.8 0.4 3.9e-44 150.2 0.4 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CDJ81749.1 - 4.2e-24 85.4 0.0 9.4e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Bax1-I PF01027.20 CDJ81750.1 - 2.8e-15 56.7 24.7 3.1e-15 56.6 24.7 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 CDJ81750.1 - 2.3 7.7 18.1 2.6 7.5 18.1 1.0 1 0 0 1 1 1 0 Bax inhibitor 1 like DUF229 PF02995.17 CDJ81752.1 - 1.1e-14 54.0 1.1 3.2e-07 29.3 0.2 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF229) Patched PF02460.18 CDJ81753.1 - 8.4e-104 348.3 11.8 2.5e-102 343.4 11.8 2.0 1 1 0 1 1 1 1 Patched family ACR_tran PF00873.19 CDJ81753.1 - 1.1 6.8 7.3 11 3.5 5.8 2.1 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family DUF1712 PF08217.11 CDJ81755.1 - 1e-29 103.5 0.4 4.8e-22 78.2 0.4 2.9 2 2 1 3 3 3 2 Fungal domain of unknown function (DUF1712) DUF4372 PF14294.6 CDJ81755.1 - 0.06 13.5 0.1 7.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4372) CDK2AP PF09806.9 CDJ81756.1 - 0.01 16.0 0.6 0.011 15.8 0.6 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Nup88 PF10168.9 CDJ81756.1 - 0.011 13.6 1.3 0.012 13.5 1.3 1.1 1 0 0 1 1 1 0 Nuclear pore component Rad50_zn_hook PF04423.14 CDJ81756.1 - 0.081 12.8 0.5 0.081 12.8 0.5 2.1 2 1 0 2 2 2 0 Rad50 zinc hook motif DUF4451 PF14616.6 CDJ81756.1 - 0.13 12.5 0.8 0.28 11.4 0.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4451) Beta_helix PF13229.6 CDJ81757.1 - 0.017 15.0 0.3 0.024 14.5 0.3 1.3 1 0 0 1 1 1 0 Right handed beta helix region Beta_helix PF13229.6 CDJ81758.1 - 1.4e-08 34.8 20.0 0.0098 15.8 0.1 3.3 2 1 1 3 3 3 3 Right handed beta helix region PRP4 PF08799.11 CDJ81758.1 - 0.1 12.2 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like RT_RNaseH_2 PF17919.1 CDJ81759.1 - 1.3e-26 92.5 0.1 2.5e-26 91.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ81759.1 - 1.7e-25 89.3 0.1 3.3e-25 88.4 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ81759.1 - 3.5e-14 52.9 0.0 7.6e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_12 PF13087.6 CDJ81759.1 - 1.2e-13 51.2 0.0 1.9e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain gag-asp_proteas PF13975.6 CDJ81759.1 - 4.4e-05 24.0 0.0 0.00012 22.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ81759.1 - 8.2e-05 22.9 0.0 0.00024 21.4 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ81759.1 - 0.0013 19.3 0.0 0.0029 18.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 CDJ81759.1 - 0.0027 17.5 0.0 0.0063 16.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease UvrD_C_2 PF13538.6 CDJ81759.1 - 0.037 13.8 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 CDJ81759.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Actin PF00022.19 CDJ81760.1 - 2.3e-111 372.3 0.0 1.7e-110 369.4 0.0 1.9 1 1 0 1 1 1 1 Actin DUF4962 PF16332.5 CDJ81760.1 - 0.25 9.8 0.0 0.4 9.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) Ground-like PF04155.18 CDJ81761.1 - 2.3e-16 60.2 0.7 2.3e-16 60.2 0.7 3.7 3 0 0 3 3 3 1 Ground-like domain Coat_F PF07875.12 CDJ81761.1 - 3 8.1 8.0 5.3 7.4 0.1 3.1 2 1 1 3 3 3 0 Coat F domain Fringe PF02434.16 CDJ81762.1 - 3.3e-13 49.7 0.1 2.3e-12 46.9 0.1 2.0 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 CDJ81762.1 - 1.6e-09 37.9 0.1 1.2e-06 28.5 0.5 2.3 2 0 0 2 2 2 2 Galactosyltransferase DUF1236 PF06823.12 CDJ81762.1 - 0.18 11.7 1.7 0.29 11.0 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1236) RVT_1 PF00078.27 CDJ81763.1 - 4.8e-30 104.7 0.1 5.4e-30 104.6 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1907 PF08925.11 CDJ81764.1 - 4.6e-101 338.0 0.0 5.5e-101 337.7 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) Lectin_C PF00059.21 CDJ81766.1 - 2.3e-08 34.7 0.6 3.2e-08 34.3 0.6 1.2 1 0 0 1 1 1 1 Lectin C-type domain Y_phosphatase PF00102.27 CDJ81767.1 - 7.1e-54 182.9 0.0 9.5e-54 182.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ81767.1 - 3.3e-07 30.2 0.0 5.6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDJ81767.1 - 0.00022 21.3 0.0 0.00059 19.9 0.0 1.7 1 1 1 2 2 2 1 Tyrosine phosphatase family Myotub-related PF06602.14 CDJ81767.1 - 0.015 14.2 0.0 0.02 13.8 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Bac_DnaA PF00308.18 CDJ81767.1 - 0.076 12.8 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Bacterial dnaA protein Sugar_tr PF00083.24 CDJ81768.1 - 3.2e-33 115.3 12.0 5.2e-33 114.6 12.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ81768.1 - 4.1e-19 68.7 15.6 1.8e-18 66.6 14.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CoA_binding_3 PF13727.6 CDJ81768.1 - 0.17 11.9 9.5 0.19 11.7 0.0 2.8 3 0 0 3 3 3 0 CoA-binding domain Y_phosphatase PF00102.27 CDJ81769.1 - 5.6e-71 238.8 1.0 8.4e-71 238.3 1.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ81769.1 - 2.4e-06 27.4 0.1 7e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDJ81769.1 - 2.4e-05 24.4 0.0 0.00038 20.5 0.0 2.3 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CDJ81769.1 - 0.043 13.9 0.1 0.14 12.3 0.0 1.9 1 1 0 1 1 1 0 Inositol hexakisphosphate STELLO PF03385.17 CDJ81770.1 - 7.4e-26 90.9 0.0 9.2e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 STELLO glycosyltransferases DUF2358 PF10184.9 CDJ81770.1 - 0.072 13.4 0.9 0.17 12.1 0.5 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2358) Serpin PF00079.20 CDJ81771.1 - 1.1e-80 271.7 1.6 1.3e-80 271.5 1.6 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) adh_short PF00106.25 CDJ81772.1 - 2.5e-27 95.6 0.0 4.2e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ81772.1 - 1.2e-17 64.2 0.0 1.9e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TPR_12 PF13424.6 CDJ81773.1 - 2.8e-08 33.9 1.5 1.9e-07 31.3 0.4 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ81773.1 - 1.9e-05 24.3 3.4 1.3 9.0 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ81773.1 - 3.1e-05 23.6 0.6 0.37 10.5 0.1 3.4 3 0 0 3 3 3 3 TPR repeat TPR_8 PF13181.6 CDJ81773.1 - 0.0001 22.2 1.1 7.3 7.1 0.1 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ81773.1 - 0.0046 17.0 2.0 4.7 7.6 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ81773.1 - 0.065 13.3 0.2 53 4.2 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat I-set PF07679.16 CDJ81774.1 - 1.3e-12 47.6 0.0 1.7e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ81774.1 - 8.8e-07 29.4 0.0 1.4e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain zf-C2H2 PF00096.26 CDJ81775.1 - 0.0067 16.8 3.9 0.0067 16.8 3.9 3.2 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-C2HE PF16278.5 CDJ81775.1 - 3.1 8.3 8.0 7.7 7.0 0.3 3.0 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_2 PF13465.6 CDJ81775.1 - 4.2 8.0 11.7 0.69 10.5 2.8 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_2 PF12756.7 CDJ81775.1 - 4.9 7.5 9.2 4.9 7.6 4.2 2.7 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) NuA4 PF09340.10 CDJ81777.1 - 2.5e-14 52.9 0.1 5.7e-14 51.8 0.1 1.6 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 WBP-1 PF11669.8 CDJ81778.1 - 0.0047 17.5 0.2 0.034 14.8 0.2 2.1 1 1 0 1 1 1 1 WW domain-binding protein 1 DUF1908 PF08926.11 CDJ81779.1 - 3.3e-72 243.0 3.1 3.3e-72 243.0 3.1 3.1 3 1 0 3 3 2 1 Domain of unknown function (DUF1908) Pkinase PF00069.25 CDJ81779.1 - 8.7e-65 218.7 0.0 1.5e-64 217.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ81779.1 - 3.8e-29 101.7 0.0 1e-28 100.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase PDZ_6 PF17820.1 CDJ81779.1 - 1.2e-10 41.0 0.0 2.7e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CDJ81779.1 - 1.8e-09 37.8 0.0 3.5e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ81779.1 - 6.9e-07 29.5 0.0 1.5e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain APH PF01636.23 CDJ81779.1 - 6.6e-06 26.2 0.0 0.057 13.3 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CDJ81779.1 - 4.8e-05 22.8 0.0 0.00016 21.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CDJ81779.1 - 0.026 13.5 0.0 0.048 12.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_C PF00433.24 CDJ81779.1 - 0.059 14.1 0.5 0.3 11.8 0.1 2.6 2 0 0 2 2 2 0 Protein kinase C terminal domain Kdo PF06293.14 CDJ81779.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GST_N PF02798.20 CDJ81780.1 - 7.2e-14 51.9 0.0 1.7e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CDJ81780.1 - 4.1e-13 49.4 0.0 6.3e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDJ81780.1 - 1.7e-05 24.9 0.0 3.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDJ81780.1 - 0.00064 20.1 0.0 0.0016 18.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 CDJ81780.1 - 0.0012 19.6 0.0 0.0025 18.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 CDJ81780.1 - 0.022 15.1 0.0 0.036 14.4 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_N_2 PF13409.6 CDJ81780.1 - 0.023 15.0 0.0 0.067 13.5 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Glu_syn_central PF04898.14 CDJ81781.1 - 0.0026 17.3 0.1 0.0043 16.6 0.1 1.2 1 0 0 1 1 1 1 Glutamate synthase central domain SID-1_RNA_chan PF13965.6 CDJ81781.1 - 0.0054 15.2 0.4 0.0067 14.9 0.4 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Protocadherin PF08374.11 CDJ81781.1 - 0.022 14.7 3.8 0.086 12.8 0.0 2.1 2 0 0 2 2 2 0 Protocadherin TNFR_16_TM PF18422.1 CDJ81781.1 - 0.025 14.5 1.0 0.053 13.5 1.0 1.4 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF3328 PF11807.8 CDJ81781.1 - 0.026 14.3 0.0 0.04 13.7 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) MIG-14_Wnt-bd PF06664.12 CDJ81781.1 - 0.062 12.5 0.0 0.086 12.1 0.0 1.1 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion DUF2207 PF09972.9 CDJ81781.1 - 0.074 11.8 0.1 0.074 11.8 0.1 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) EphA2_TM PF14575.6 CDJ81781.1 - 0.19 12.7 1.1 0.55 11.1 1.1 1.9 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 CDJ81781.1 - 0.28 11.5 0.2 0.28 11.5 0.2 2.0 2 0 0 2 2 2 0 Orf78 (ac78) TMEM154 PF15102.6 CDJ81781.1 - 0.47 10.4 0.1 0.47 10.4 0.1 2.5 2 1 0 2 2 2 0 TMEM154 protein family zf-CCCH PF00642.24 CDJ81782.1 - 1e-17 63.6 5.3 6.9e-10 38.6 0.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ81782.1 - 4.3e-11 42.5 7.0 1.2e-05 25.2 1.0 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 CDJ81782.1 - 7.6e-11 41.5 4.4 0.00013 21.7 0.2 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CDJ81782.1 - 1.3e-05 25.5 5.4 0.028 14.9 0.6 2.6 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CDJ81782.1 - 0.021 15.5 5.1 1.8 9.3 0.3 2.4 2 0 0 2 2 2 0 Torus domain 7TM_GPCR_Srsx PF10320.9 CDJ81784.1 - 5.6e-23 81.6 14.5 6.7e-23 81.4 14.5 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF3267 PF11667.8 CDJ81784.1 - 0.0051 17.1 4.1 0.0051 17.1 4.1 2.6 1 1 2 3 3 3 1 Putative zincin peptidase PIG-F PF06699.11 CDJ81784.1 - 0.12 12.6 6.7 0.028 14.6 1.6 1.9 2 0 0 2 2 2 0 GPI biosynthesis protein family Pig-F DUF2207 PF09972.9 CDJ81784.1 - 0.12 11.1 15.0 0.016 14.0 2.1 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Orthopox_A36R PF05950.11 CDJ81784.1 - 0.39 10.9 7.1 0.16 12.1 3.4 1.9 2 0 0 2 2 2 0 Orthopoxvirus A36R protein RVT_1 PF00078.27 CDJ81785.1 - 9.7e-15 54.7 0.0 1.3e-14 54.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MetOD1 PF18546.1 CDJ81785.1 - 0.0015 18.5 0.0 0.0022 18.0 0.0 1.2 1 0 0 1 1 1 1 Metanogen output domain 1 EntA_Immun PF08951.10 CDJ81785.1 - 0.08 13.3 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Enterocin A Immunity 7TM_GPCR_Srv PF10323.9 CDJ81786.1 - 0.014 14.8 15.1 0.024 14.0 15.1 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Rif1_N PF12231.8 CDJ81788.1 - 0.021 13.8 2.1 0.032 13.2 0.1 2.0 2 0 0 2 2 2 0 Rap1-interacting factor 1 N terminal Lectin_C PF00059.21 CDJ81789.1 - 1.1e-15 58.3 0.7 1.4e-15 58.0 0.7 1.1 1 0 0 1 1 1 1 Lectin C-type domain CH PF00307.31 CDJ81790.1 - 2.1e-41 140.5 0.5 4.6e-21 75.1 1.3 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain Filamin PF00630.19 CDJ81790.1 - 1.3e-08 35.5 0.0 9.6e-05 23.2 0.0 2.5 2 0 0 2 2 2 2 Filamin/ABP280 repeat CAMSAP_CH PF11971.8 CDJ81790.1 - 1.3e-05 25.0 0.0 0.0055 16.5 0.0 2.7 2 0 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 CDJ81790.1 - 6.4e-05 23.0 1.9 0.21 11.7 0.0 2.3 2 0 0 2 2 2 2 CH-like domain in sperm protein 7tm_1 PF00001.21 CDJ81791.1 - 8.7e-06 25.2 6.8 1.2e-05 24.8 6.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MFS_1 PF07690.16 CDJ81792.1 - 2.4e-25 89.2 27.7 3e-25 88.9 27.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 CDJ81792.1 - 0.00053 19.4 5.3 0.0081 15.5 0.3 2.3 1 1 1 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF1440 PF07274.12 CDJ81792.1 - 0.053 13.9 4.0 0.051 13.9 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) CbtA PF09490.10 CDJ81792.1 - 0.071 12.9 0.3 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) Prion_bPrPp PF11587.8 CDJ81792.1 - 0.12 12.3 0.2 0.5 10.2 0.0 2.1 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal Ion_trans_2 PF07885.16 CDJ81793.1 - 1.9e-24 85.4 17.2 6.5e-17 61.3 0.1 2.7 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CDJ81793.1 - 0.0029 16.9 0.1 0.0029 16.9 0.1 3.0 2 1 1 3 3 3 1 Ion transport protein GBP PF02263.19 CDJ81794.1 - 1e-95 319.9 0.0 1.4e-95 319.5 0.0 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 CDJ81794.1 - 1.5e-10 40.9 0.6 2.4e-10 40.3 0.6 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain Tiam_CC_Ex PF18385.1 CDJ81794.1 - 0.014 15.8 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 T-lymphoma invasion and metastasis CC-Ex domain Activin_recp PF01064.23 CDJ81795.1 - 0.0099 17.0 9.1 0.015 16.4 9.1 1.3 1 0 0 1 1 1 1 Activin types I and II receptor domain QVR PF17064.5 CDJ81795.1 - 0.025 14.8 6.7 0.28 11.5 0.8 2.3 1 1 1 2 2 2 0 Sleepless protein dCache_1 PF02743.18 CDJ81796.1 - 2.5e-12 47.1 0.2 5e-10 39.6 0.0 2.8 3 1 0 3 3 3 2 Cache domain VGCC_alpha2 PF08473.11 CDJ81796.1 - 1.6e-06 27.2 2.9 0.0002 20.3 0.9 3.2 2 1 0 2 2 2 2 Neuronal voltage-dependent calcium channel alpha 2acd VWA PF00092.28 CDJ81796.1 - 8.4e-06 26.1 0.0 1.5e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Pap_E4 PF02711.14 CDJ81796.1 - 0.039 14.9 0.0 0.12 13.3 0.0 1.8 1 0 0 1 1 1 0 E4 protein Tyrosinase PF00264.20 CDJ81797.1 - 2.9e-21 76.8 2.0 4.3e-15 56.6 0.8 2.3 1 1 1 2 2 2 2 Common central domain of tyrosinase ShK PF01549.24 CDJ81797.1 - 0.00023 21.6 9.7 0.00059 20.3 9.7 1.8 1 0 0 1 1 1 1 ShK domain-like Serine_rich PF08824.10 CDJ81797.1 - 0.0036 17.3 0.0 0.0052 16.8 0.0 1.2 1 0 0 1 1 1 1 Serine rich protein interaction domain Runt PF00853.19 CDJ81798.1 - 1.3e-48 163.8 0.0 1.7e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Runt domain RRM_7 PF16367.5 CDJ81799.1 - 9.3e-32 109.0 0.1 3.4e-31 107.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif CEBP_ZZ PF16366.5 CDJ81799.1 - 5.5e-24 84.2 6.9 1.2e-23 83.1 6.9 1.6 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 CDJ81799.1 - 1.8e-07 30.8 0.0 0.00046 19.9 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_3rep PF18868.1 CDJ81802.1 - 0.66 10.7 4.3 3.8 8.2 1.2 2.6 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats P53 PF00870.18 CDJ81803.1 - 7e-49 166.2 0.7 7e-49 166.2 0.7 1.9 2 0 0 2 2 2 1 P53 DNA-binding domain Spt20 PF12090.8 CDJ81803.1 - 3 7.4 15.5 4.8 6.7 15.5 1.2 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 CDJ81803.1 - 3.5 6.3 4.7 5 5.8 4.7 1.2 1 0 0 1 1 1 0 Presenilin Roughex PF06020.11 CDJ81803.1 - 3.6 6.6 6.4 7.5 5.5 4.4 2.0 2 0 0 2 2 2 0 Drosophila roughex protein DUF929 PF06053.11 CDJ81804.1 - 0.036 13.4 0.1 0.064 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF929) QSOX_Trx1 PF18108.1 CDJ81804.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 QSOX Trx-like domain Sugar_tr PF00083.24 CDJ81805.1 - 6.7e-17 61.5 2.3 8.3e-17 61.2 2.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ81805.1 - 5.7e-07 28.8 2.2 7.8e-07 28.3 2.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF5345 PF17280.2 CDJ81805.1 - 6.5 6.8 7.0 0.94 9.5 0.4 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Bromodomain PF00439.25 CDJ81806.1 - 5.5e-20 71.2 0.0 1.2e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 Bromodomain MBD PF01429.19 CDJ81806.1 - 1.4e-17 63.1 1.1 2e-17 62.7 0.0 1.9 2 0 0 2 2 1 1 Methyl-CpG binding domain WSD PF15613.6 CDJ81806.1 - 5.9e-12 45.9 0.0 5.9e-12 45.9 0.0 4.6 4 0 0 4 4 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD PF00628.29 CDJ81806.1 - 1.9e-06 27.6 32.1 0.00063 19.6 14.5 3.0 2 0 0 2 2 2 2 PHD-finger WHIM1 PF15612.6 CDJ81806.1 - 2.7e-05 23.6 0.1 6.9e-05 22.3 0.1 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DDT PF02791.17 CDJ81806.1 - 0.00028 21.1 0.1 0.0013 19.0 0.1 2.2 1 0 0 1 1 1 1 DDT domain Flagellin_IN PF07196.13 CDJ81806.1 - 0.15 12.2 0.9 0.45 10.8 0.9 1.8 1 0 0 1 1 1 0 Flagellin hook IN motif MDM10 PF12519.8 CDJ81806.1 - 0.24 10.2 16.9 0.22 10.3 13.2 2.3 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 DUF4175 PF13779.6 CDJ81806.1 - 0.52 8.1 40.5 1 7.2 40.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FHIPEP PF00771.20 CDJ81806.1 - 0.72 8.2 9.7 1.4 7.3 9.7 1.4 1 0 0 1 1 1 0 FHIPEP family V_ATPase_I PF01496.19 CDJ81806.1 - 0.82 7.5 19.8 0.47 8.3 17.0 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family PIP5K PF01504.18 CDJ81806.1 - 1.1 8.4 13.5 3.3 6.9 13.5 1.7 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase CAF1 PF04857.20 CDJ81806.1 - 1.5 7.9 10.9 0.32 10.1 6.8 1.9 2 0 0 2 2 2 0 CAF1 family ribonuclease Serinc PF03348.15 CDJ81806.1 - 1.5 7.6 9.6 3.5 6.4 9.6 1.5 1 0 0 1 1 1 0 Serine incorporator (Serinc) Cellulose_synt PF03552.14 CDJ81806.1 - 1.8 6.9 5.0 3.1 6.2 5.0 1.2 1 0 0 1 1 1 0 Cellulose synthase PHD_2 PF13831.6 CDJ81806.1 - 1.8 8.2 18.6 3.3 7.3 6.6 2.8 2 0 0 2 2 2 0 PHD-finger MAT1 PF06391.13 CDJ81806.1 - 2 8.2 28.5 0.19 11.6 20.6 3.0 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 CSG2 PF16965.5 CDJ81806.1 - 2.4 7.0 11.0 1.3 7.8 8.8 1.6 2 0 0 2 2 2 0 Ceramide synthase regulator Hid1 PF12722.7 CDJ81806.1 - 5.2 5.1 21.0 9.7 4.2 21.0 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SID-1_RNA_chan PF13965.6 CDJ81806.1 - 6.3 5.1 10.2 11 4.3 10.2 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 EIIBC-GUT_N PF03612.14 CDJ81806.1 - 6.6 6.4 15.5 30 4.3 15.5 2.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus hDGE_amylase PF14701.6 CDJ81806.1 - 7.1 5.6 12.1 17 4.3 12.1 1.6 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain CLN3 PF02487.17 CDJ81806.1 - 8.2 5.4 15.0 18 4.2 15.0 1.5 1 0 0 1 1 1 0 CLN3 protein Thioredoxin PF00085.20 CDJ81807.1 - 3.4e-23 81.6 0.0 5.6e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 CDJ81807.1 - 4.4e-15 56.1 0.0 1.7e-10 41.1 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CDJ81807.1 - 0.11 12.9 0.1 0.35 11.3 0.1 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain ABC_membrane PF00664.23 CDJ81808.1 - 6.4e-79 265.4 25.0 1.5e-54 185.6 8.1 2.4 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ81808.1 - 2.6e-69 232.0 0.5 1.6e-33 116.1 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CDJ81808.1 - 4.4e-15 55.7 1.9 3.1e-06 26.8 0.0 3.5 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDJ81808.1 - 9e-09 35.9 0.3 0.00038 20.9 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CDJ81808.1 - 1.5e-07 31.8 1.4 0.0016 18.7 0.0 3.7 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 CDJ81808.1 - 4.9e-06 25.6 1.1 0.051 12.4 0.2 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 CDJ81808.1 - 6.2e-06 26.2 0.0 0.16 11.9 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 CDJ81808.1 - 8.9e-06 26.2 1.2 0.44 11.0 0.0 3.9 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 CDJ81808.1 - 5.2e-05 23.1 0.1 0.025 14.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 CDJ81808.1 - 7.3e-05 22.6 0.0 0.028 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CDJ81808.1 - 0.00012 21.8 0.1 0.56 10.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Rad17 PF03215.15 CDJ81808.1 - 0.00021 21.2 0.1 0.14 12.0 0.0 2.9 2 0 0 2 2 2 1 Rad17 P-loop domain SbcCD_C PF13558.6 CDJ81808.1 - 0.00026 21.2 3.8 0.42 10.9 0.5 3.9 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 CDJ81808.1 - 0.00037 21.1 0.0 0.16 12.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 CDJ81808.1 - 0.00039 19.7 0.0 0.022 13.9 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit Zeta_toxin PF06414.12 CDJ81808.1 - 0.00039 19.8 0.0 0.017 14.4 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 CDJ81808.1 - 0.0011 18.5 0.0 0.28 10.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 CDJ81808.1 - 0.0011 18.1 0.0 0.23 10.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 CDJ81808.1 - 0.0012 18.8 0.1 1 9.3 0.0 4.0 4 1 0 4 4 4 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CDJ81808.1 - 0.0021 17.8 0.8 1.1 9.0 0.0 4.0 4 0 0 4 4 4 1 IstB-like ATP binding protein APS_kinase PF01583.20 CDJ81808.1 - 0.0022 17.9 0.2 0.32 10.9 0.0 2.8 3 0 0 3 3 2 1 Adenylylsulphate kinase AAA_30 PF13604.6 CDJ81808.1 - 0.0032 17.2 1.4 1.2 8.8 0.1 3.3 2 2 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CDJ81808.1 - 0.0033 17.7 0.4 0.31 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 CDJ81808.1 - 0.0043 16.8 0.0 0.43 10.3 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 CDJ81808.1 - 0.0058 17.0 0.0 3.9 7.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.23 CDJ81808.1 - 0.0058 16.7 0.0 5.9 7.0 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_21 PF13304.6 CDJ81808.1 - 0.006 16.4 0.1 0.36 10.6 0.0 3.2 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 CDJ81808.1 - 0.017 14.7 0.0 6.1 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain tRNA_lig_kinase PF08303.11 CDJ81808.1 - 0.018 15.1 0.3 1.5 8.9 0.0 3.4 3 0 0 3 3 3 0 tRNA ligase kinase domain AAA_33 PF13671.6 CDJ81808.1 - 0.022 14.9 0.6 5.2 7.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 CDJ81808.1 - 0.022 14.8 0.3 1.6 8.7 0.0 2.7 2 1 0 2 2 2 0 Helicase HerA, central domain NB-ARC PF00931.22 CDJ81808.1 - 0.06 12.5 0.3 3.6 6.7 0.0 2.6 3 0 0 3 3 2 0 NB-ARC domain SRP54 PF00448.22 CDJ81808.1 - 0.071 12.7 0.1 5.1 6.7 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Mg_chelatase PF01078.21 CDJ81808.1 - 0.096 12.1 0.0 5.6 6.3 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 CDJ81808.1 - 0.14 11.9 0.4 4.4 7.0 0.0 2.7 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase TSP_1 PF00090.19 CDJ81809.1 - 1e-07 32.0 14.9 1e-07 32.0 14.9 4.0 5 0 0 5 5 5 1 Thrombospondin type 1 domain THAP PF05485.12 CDJ81810.1 - 1.5e-15 57.9 11.1 0.0011 19.8 0.7 6.4 5 1 1 6 6 6 5 THAP domain Cornichon PF03311.14 CDJ81811.1 - 2.8e-40 137.4 11.4 3.6e-40 137.1 11.4 1.1 1 0 0 1 1 1 1 Cornichon protein Phage_holin_3_6 PF07332.11 CDJ81811.1 - 0.2 11.7 0.2 0.2 11.7 0.2 2.3 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2534 PF10749.9 CDJ81811.1 - 1.2 9.3 13.8 0.6 10.3 5.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2534) DHHC PF01529.20 CDJ81811.1 - 2.1 8.4 14.0 0.26 11.4 6.8 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase ANAPC3 PF12895.7 CDJ81813.1 - 0.4 10.9 4.3 0.71 10.1 3.4 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR_long PF17177.4 CDJ81815.1 - 0.00018 21.0 1.7 0.00062 19.2 0.1 2.7 3 1 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 CDJ81815.1 - 0.0021 18.6 9.4 0.95 10.0 2.6 5.3 3 1 1 4 4 4 1 Tetratricopeptide repeat HHH_6 PF14579.6 CDJ81815.1 - 0.0041 17.4 1.0 1.9 8.8 0.0 4.0 4 0 0 4 4 4 1 Helix-hairpin-helix motif TPR_21 PF09976.9 CDJ81815.1 - 0.0077 16.0 4.4 0.04 13.6 1.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat-like domain MMR_HSR1_C PF08438.10 CDJ81815.1 - 0.013 16.1 1.9 0.03 14.9 0.2 2.7 2 0 0 2 2 2 0 GTPase of unknown function C-terminal PPR_3 PF13812.6 CDJ81815.1 - 0.028 14.5 0.0 0.52 10.4 0.0 3.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain PPR_2 PF13041.6 CDJ81815.1 - 0.069 13.4 0.1 2.3e+02 2.1 0.0 5.3 4 1 1 5 5 5 0 PPR repeat family PPR PF01535.20 CDJ81815.1 - 0.081 13.2 3.4 76 3.9 0.1 5.5 5 0 0 5 5 5 0 PPR repeat PPR_1 PF12854.7 CDJ81815.1 - 0.12 12.1 0.5 1.4e+02 2.2 0.1 4.6 5 0 0 5 5 5 0 PPR repeat TPR_12 PF13424.6 CDJ81815.1 - 0.38 11.1 2.9 12 6.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ81815.1 - 3 7.8 4.5 16 5.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat BTG PF07742.12 CDJ81817.1 - 0.00012 21.9 0.0 0.00032 20.5 0.0 1.8 1 1 0 1 1 1 1 BTG family PQQ PF01011.21 CDJ81817.1 - 0.19 11.8 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 PQQ enzyme repeat Sin_N PF04801.13 CDJ81818.1 - 0.23 10.6 8.3 0.41 9.8 8.3 1.3 1 0 0 1 1 1 0 Sin-like protein conserved region ING PF12998.7 CDJ81819.1 - 1.7e-18 67.0 9.1 1.7e-18 67.0 9.1 1.6 2 0 0 2 2 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CDJ81819.1 - 5.2e-06 26.3 10.0 1e-05 25.3 10.0 1.5 1 0 0 1 1 1 1 PHD-finger Apolipoprotein PF01442.18 CDJ81819.1 - 0.001 19.0 9.6 0.0025 17.7 9.4 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Senescence PF06911.12 CDJ81819.1 - 0.012 15.9 4.7 0.02 15.2 4.8 1.4 1 1 0 1 1 1 0 Senescence-associated protein BLOC1_2 PF10046.9 CDJ81819.1 - 0.029 14.6 9.1 0.077 13.3 0.2 2.9 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3106 PF11304.8 CDJ81819.1 - 0.036 14.5 2.0 0.036 14.5 2.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) Osmo_CC PF08946.10 CDJ81819.1 - 0.042 14.1 9.9 0.066 13.5 2.3 2.5 2 0 0 2 2 2 0 Osmosensory transporter coiled coil PHD_2 PF13831.6 CDJ81819.1 - 0.042 13.4 3.1 0.078 12.5 3.1 1.5 1 0 0 1 1 1 0 PHD-finger DUF2362 PF10154.9 CDJ81819.1 - 0.047 12.7 14.2 0.059 12.3 14.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Prominin PF05478.11 CDJ81819.1 - 0.058 11.4 4.1 0.072 11.0 4.1 1.1 1 0 0 1 1 1 0 Prominin Fzo_mitofusin PF04799.13 CDJ81819.1 - 0.097 12.2 6.3 0.15 11.6 4.9 1.9 1 1 1 2 2 2 0 fzo-like conserved region ALMT PF11744.8 CDJ81819.1 - 0.11 11.3 11.8 0.14 11.0 11.8 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Histidinol_dh PF00815.20 CDJ81819.1 - 0.18 10.8 7.7 0.52 9.3 0.7 2.1 1 1 1 2 2 2 0 Histidinol dehydrogenase CCDC-167 PF15188.6 CDJ81819.1 - 0.35 11.3 11.4 4.1 7.8 9.3 2.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF3086 PF11285.8 CDJ81819.1 - 0.64 9.1 11.1 0.07 12.2 6.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) Perilipin PF03036.16 CDJ81819.1 - 0.73 8.8 9.1 0.91 8.5 9.1 1.1 1 0 0 1 1 1 0 Perilipin family COG2 PF06148.11 CDJ81819.1 - 0.83 9.7 8.7 0.093 12.8 1.9 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3584 PF12128.8 CDJ81819.1 - 0.98 6.8 17.1 1.2 6.5 17.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1192 PF06698.11 CDJ81819.1 - 1.1 9.3 6.7 3.1 7.9 1.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) XhlA PF10779.9 CDJ81819.1 - 2.2 8.6 10.7 9.3 6.5 1.1 3.5 1 1 2 3 3 3 0 Haemolysin XhlA Casc1 PF12366.8 CDJ81819.1 - 3 7.3 14.4 0.083 12.4 6.7 2.0 1 1 1 2 2 2 0 Cancer susceptibility candidate 1 MtrG PF04210.13 CDJ81819.1 - 4.2 7.3 5.6 1.5 8.7 0.5 2.4 2 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Fib_alpha PF08702.10 CDJ81819.1 - 6 7.1 14.9 0.19 11.9 7.0 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PhoU PF01895.19 CDJ81819.1 - 6.8 7.2 9.5 3.7 8.1 3.2 2.5 1 1 1 2 2 2 0 PhoU domain Exonuc_VII_L PF02601.15 CDJ81819.1 - 7.4 6.0 10.7 12 5.4 10.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Rota_NSP4 PF01452.16 CDJ81820.1 - 0.16 11.6 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Rotavirus non structural protein 7TM_GPCR_Srab PF10292.9 CDJ81821.1 - 3.2e-35 121.6 23.8 3.9e-35 121.3 23.8 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Sra PF02117.16 CDJ81821.1 - 2.4e-21 75.9 27.1 2.8e-21 75.7 27.1 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sra 7TM_GPCR_Srb PF02175.16 CDJ81821.1 - 0.00015 21.6 18.9 0.00015 21.6 18.9 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srb L51_S25_CI-B8 PF05047.16 CDJ81822.1 - 1.7e-06 27.8 0.0 3.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Pkinase PF00069.25 CDJ81823.1 - 2.3e-64 217.3 0.0 2.9e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ81823.1 - 4e-28 98.4 0.0 5.5e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ81823.1 - 1e-07 31.6 0.0 1.1e-06 28.2 0.0 1.9 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 CDJ81823.1 - 0.0045 16.6 0.5 2.3 7.8 0.0 2.6 2 1 1 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CDJ81823.1 - 0.019 14.4 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ81823.1 - 0.021 14.8 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Clat_adaptor_s PF01217.20 CDJ81823.1 - 0.075 13.0 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Clathrin adaptor complex small chain UBX PF00789.20 CDJ81824.1 - 2.8e-17 62.7 0.0 4.7e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 CDJ81824.1 - 2.1e-09 37.1 0.2 7e-09 35.4 0.1 2.0 2 0 0 2 2 2 1 UBA/TS-N domain DUF3827 PF12877.7 CDJ81824.1 - 0.037 12.4 7.8 0.044 12.2 7.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) ZapB PF06005.12 CDJ81825.1 - 0.018 15.5 0.8 0.09 13.2 0.3 2.0 2 0 0 2 2 2 0 Cell division protein ZapB DMPK_coil PF08826.10 CDJ81825.1 - 0.27 11.4 2.3 0.61 10.2 2.3 1.6 1 0 0 1 1 1 0 DMPK coiled coil domain like DivIC PF04977.15 CDJ81825.1 - 0.32 10.8 4.3 9.7 6.0 0.1 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF2508 PF10704.9 CDJ81825.1 - 1.7 8.9 3.7 15 5.9 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2508) LysM PF01476.20 CDJ81826.1 - 2.6e-09 37.0 0.1 7.6e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 LysM domain PhaP_Bmeg PF09602.10 CDJ81826.1 - 0.16 11.9 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Ribosomal_L4 PF00573.22 CDJ81827.1 - 3.1e-36 124.9 0.0 4.8e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CDJ81827.1 - 5.7e-21 74.3 4.3 1.1e-20 73.4 4.3 1.5 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain E3_UbLigase_R4 PF13764.6 CDJ81828.1 - 4.8e-184 613.8 5.5 5.4e-183 610.3 0.2 3.1 2 1 0 2 2 2 1 E3 ubiquitin-protein ligase UBR4 zf-UBR PF02207.20 CDJ81828.1 - 1.2e-07 31.8 14.8 1.2e-07 31.8 14.8 3.1 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) DNA_PPF PF02916.15 CDJ81828.1 - 0.00024 21.5 0.0 0.00076 19.9 0.0 1.9 1 0 0 1 1 1 1 DNA polymerase processivity factor Cnn_1N PF07989.11 CDJ81828.1 - 0.02 15.0 0.5 0.17 12.0 1.2 2.3 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 THAP PF05485.12 CDJ81829.1 - 0.016 16.1 0.2 0.027 15.4 0.2 1.5 1 1 0 1 1 1 0 THAP domain SPT16 PF08644.11 CDJ81830.1 - 2.8e-56 189.9 0.1 2.8e-56 189.9 0.1 2.1 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 CDJ81830.1 - 2.1e-38 131.6 0.3 7.9e-38 129.8 0.3 2.1 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 CDJ81830.1 - 4.6e-23 82.0 0.0 7.4e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 CDJ81830.1 - 7.2e-17 61.6 0.1 2.4e-16 59.9 0.1 2.0 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Abhydrolase_1 PF00561.20 CDJ81831.1 - 6.1e-25 88.3 0.1 3.4e-24 85.9 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ81831.1 - 1.2e-20 75.1 1.7 1.5e-20 74.8 1.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDJ81831.1 - 4.2e-13 49.1 0.0 5.8e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 CDJ81831.1 - 0.00019 21.3 0.0 0.00063 19.6 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase Ndr PF03096.14 CDJ81831.1 - 0.00032 19.5 0.0 0.00082 18.2 0.0 1.7 1 0 0 1 1 1 1 Ndr family PAF-AH_p_II PF03403.13 CDJ81831.1 - 0.00072 18.2 0.0 0.034 12.6 0.0 2.5 2 1 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II LIDHydrolase PF10230.9 CDJ81831.1 - 0.0034 17.0 0.0 0.0056 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase DUF3530 PF12048.8 CDJ81831.1 - 0.037 13.4 0.0 0.095 12.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) Chlorophyllase2 PF12740.7 CDJ81831.1 - 0.074 12.0 0.0 0.27 10.1 0.0 2.0 1 1 0 1 1 1 0 Chlorophyllase enzyme DUF915 PF06028.11 CDJ81831.1 - 0.074 12.4 0.1 7.1 5.9 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) 7TM_GPCR_Srab PF10292.9 CDJ81832.1 - 2.7e-05 23.3 14.7 0.00012 21.2 14.7 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor Sre PF03125.18 CDJ81832.1 - 0.0047 16.1 1.2 0.0047 16.1 1.2 2.9 2 1 2 4 4 4 1 C. elegans Sre G protein-coupled chemoreceptor RhoGEF PF00621.20 CDJ81834.1 - 4.5e-24 85.7 1.2 7.3e-24 85.0 1.2 1.4 1 0 0 1 1 1 1 RhoGEF domain Nup54 PF13874.6 CDJ81834.1 - 0.11 12.6 1.4 0.32 11.1 1.4 1.9 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 RBD PF02196.15 CDJ81834.1 - 0.11 12.6 0.0 0.65 10.1 0.0 2.4 2 0 0 2 2 2 0 Raf-like Ras-binding domain DUF892 PF05974.12 CDJ81834.1 - 0.17 11.9 0.2 0.17 11.9 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF892) LOH1CR12 PF10158.9 CDJ81834.1 - 0.2 11.7 6.5 0.074 13.1 2.6 2.3 2 1 1 3 3 3 0 Tumour suppressor protein Collagen PF01391.18 CDJ81835.1 - 5.1e-27 93.4 105.9 5.3e-11 42.1 34.5 4.1 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ81835.1 - 3.1e-21 75.2 0.8 4.6e-21 74.6 0.8 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain COX14 PF14880.6 CDJ81835.1 - 0.61 10.0 4.8 0.93 9.4 4.8 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c assembly zf-C4 PF00105.18 CDJ81836.1 - 2.3e-16 60.0 11.8 7e-16 58.5 11.8 1.9 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ81836.1 - 6.4e-13 48.8 1.0 1.2e-12 47.9 1.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Ground-like PF04155.18 CDJ81837.1 - 2e-09 38.0 0.9 5e-09 36.7 0.9 1.7 1 0 0 1 1 1 1 Ground-like domain Cornifin PF02389.15 CDJ81837.1 - 0.0095 16.1 5.1 0.014 15.6 5.1 1.3 1 0 0 1 1 1 1 Cornifin (SPRR) family Mucin PF01456.17 CDJ81837.1 - 0.24 11.4 19.5 0.43 10.6 19.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Actin PF00022.19 CDJ81838.1 - 4.5e-140 466.8 0.0 1.5e-139 465.2 0.0 1.7 1 1 0 1 1 1 1 Actin DUF4491 PF14898.6 CDJ81840.1 - 0.017 15.6 0.6 3.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) Antimicrobial10 PF08105.11 CDJ81840.1 - 0.022 14.8 0.7 6.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Metchnikowin family DUF969 PF06149.12 CDJ81840.1 - 0.086 12.2 0.5 8.2 5.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF969) MadM PF03818.13 CDJ81840.1 - 0.092 12.6 2.3 8.6 6.3 0.1 2.4 2 0 0 2 2 2 0 Malonate/sodium symporter MadM subunit OAD_gamma PF04277.13 CDJ81840.1 - 5.2 7.7 6.9 25 5.5 0.4 2.6 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Homeodomain PF00046.29 CDJ81841.1 - 6.5e-19 67.5 9.4 9.9e-19 67.0 9.4 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ81841.1 - 0.00023 21.0 1.0 0.00046 20.0 1.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain MRP-L46 PF11788.8 CDJ81841.1 - 0.076 13.8 3.0 0.11 13.2 3.0 1.2 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 DUF2475 PF10629.9 CDJ81841.1 - 0.081 13.2 2.3 2 8.7 1.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2475) TH1 PF04858.13 CDJ81842.1 - 5.4e-05 22.0 0.2 5.9e-05 21.9 0.2 1.0 1 0 0 1 1 1 1 TH1 protein Pkinase PF00069.25 CDJ81843.1 - 1.3e-65 221.4 0.0 1.9e-65 220.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ81843.1 - 7.3e-49 166.4 0.0 1.1e-48 165.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 CDJ81843.1 - 6.2e-18 65.1 7.2 1.1e-16 61.0 7.2 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Kdo PF06293.14 CDJ81843.1 - 0.00011 21.7 0.1 0.00019 20.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDJ81843.1 - 0.00073 19.2 0.1 0.0014 18.3 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 CDJ81843.1 - 0.0032 16.3 0.0 0.0061 15.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDJ81843.1 - 0.011 15.1 0.0 0.067 12.5 0.0 2.1 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 CDJ81843.1 - 0.029 14.3 0.0 0.22 11.4 0.0 2.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family GTP_EFTU PF00009.27 CDJ81844.1 - 2e-54 184.1 0.0 3.3e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CDJ81844.1 - 4.8e-16 58.9 1.0 1e-15 57.9 1.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 CDJ81844.1 - 2.4e-10 40.7 0.0 6e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 CDJ81844.1 - 0.00087 19.4 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 CDJ81844.1 - 0.11 12.3 0.1 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain HECT_2 PF09814.9 CDJ81845.1 - 3.2e-21 75.6 3.8 4.2e-21 75.2 3.8 1.2 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding H2TH PF06831.14 CDJ81845.1 - 0.013 15.4 0.0 3.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Formamidopyrimidine-DNA glycosylase H2TH domain RNase_Zc3h12a PF11977.8 CDJ81846.1 - 3.1e-23 82.3 0.2 8.3e-23 80.9 0.2 1.7 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain zf-C3HC4_2 PF13923.6 CDJ81846.1 - 1.4e-09 37.6 9.5 1.4e-09 37.6 9.5 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ81846.1 - 3.7e-08 33.6 9.2 3.7e-08 33.6 9.2 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CDJ81846.1 - 1.3e-07 31.4 11.2 1.3e-07 31.4 11.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ81846.1 - 3.9e-06 26.6 6.6 3.9e-06 26.6 6.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ81846.1 - 4.8e-05 23.3 5.2 4.8e-05 23.3 5.2 2.2 2 0 0 2 2 2 1 RING-type zinc-finger PRORP PF16953.5 CDJ81846.1 - 0.00013 21.5 1.0 0.0003 20.4 1.0 1.5 1 0 0 1 1 1 1 Protein-only RNase P zf-RING_6 PF14835.6 CDJ81846.1 - 0.00027 20.8 2.6 0.00027 20.8 2.6 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 CDJ81846.1 - 0.00043 20.5 6.4 0.0014 18.9 6.4 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 CDJ81846.1 - 0.00067 19.7 3.2 0.00067 19.7 3.2 1.8 2 0 0 2 2 2 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 CDJ81846.1 - 0.0011 18.8 8.5 0.0028 17.5 8.5 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CDJ81846.1 - 0.0067 16.6 9.8 0.0067 16.6 9.8 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CDJ81846.1 - 0.0089 16.0 8.1 0.0089 16.0 8.1 2.5 2 1 0 2 2 2 1 zinc-RING finger domain Baculo_IE-1 PF05290.11 CDJ81846.1 - 0.03 14.3 3.2 0.065 13.2 3.2 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 CDJ81846.1 - 0.042 13.6 7.5 0.12 12.2 7.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Cwf_Cwc_15 PF04889.12 CDJ81846.1 - 0.11 12.2 27.6 0.21 11.3 27.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-RING_11 PF17123.5 CDJ81846.1 - 0.91 9.3 8.7 1.1 9.1 6.4 2.2 2 0 0 2 2 2 0 RING-like zinc finger SDA1 PF05285.12 CDJ81846.1 - 5.1 6.4 25.5 9.6 5.5 25.5 1.4 1 0 0 1 1 1 0 SDA1 cNMP_binding PF00027.29 CDJ81847.1 - 6.4e-36 122.3 0.1 1.2e-10 41.4 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Patatin PF01734.22 CDJ81847.1 - 3.8e-23 82.8 0.1 8.7e-23 81.6 0.1 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase Na_K-ATPase PF00287.18 CDJ81849.1 - 1.1e-12 47.8 0.0 3.4e-12 46.1 0.0 1.7 1 1 0 1 1 1 1 Sodium / potassium ATPase beta chain LIN52 PF10044.9 CDJ81850.1 - 1.7e-21 76.7 0.0 1.9e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 Retinal tissue protein DUF1127 PF06568.11 CDJ81850.1 - 0.21 11.3 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) MCM PF00493.23 CDJ81852.1 - 2.7e-100 334.1 0.0 9.9e-100 332.2 0.0 1.9 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 CDJ81852.1 - 4.5e-34 117.0 0.3 8.6e-34 116.1 0.3 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CDJ81852.1 - 1.2e-28 99.3 1.2 2.9e-28 98.1 1.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM2_N PF12619.8 CDJ81852.1 - 9.5e-14 51.9 25.0 9.5e-14 51.9 25.0 2.4 3 0 0 3 3 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 CDJ81852.1 - 2.5e-13 50.5 0.9 7e-13 49.1 0.1 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 CDJ81852.1 - 2.1e-08 33.8 0.0 5.6e-07 29.1 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CDJ81852.1 - 3e-06 27.3 0.0 7.3e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CDJ81852.1 - 4.8e-05 23.2 0.0 0.00025 20.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cullin PF00888.22 CDJ81852.1 - 0.0027 16.4 0.6 0.0049 15.5 0.6 1.3 1 0 0 1 1 1 1 Cullin family AAA PF00004.29 CDJ81852.1 - 0.0036 17.7 0.1 0.024 15.0 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 CDJ81852.1 - 0.0036 17.1 0.2 0.024 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA lid domain Sigma54_activat PF00158.26 CDJ81852.1 - 0.01 15.5 0.0 0.37 10.5 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF648 PF04890.13 CDJ81852.1 - 0.036 13.8 0.6 0.061 13.1 0.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF648) Zn-ribbon_8 PF09723.10 CDJ81852.1 - 0.048 13.8 0.9 0.14 12.3 0.9 1.8 1 0 0 1 1 1 0 Zinc ribbon domain DUF3372 PF11852.8 CDJ81852.1 - 0.15 11.6 0.5 3.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3372) Mer2 PF09074.10 CDJ81852.1 - 1.9 8.3 6.3 0.68 9.7 2.2 2.3 2 0 0 2 2 2 0 Mer2 UDPGT PF00201.18 CDJ81853.1 - 4.9e-60 203.7 0.0 6.6e-60 203.3 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ81853.1 - 6.2e-10 39.3 0.0 1e-09 38.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 CDJ81853.1 - 0.042 13.1 0.0 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 1 DUF1980 PF09323.10 CDJ81853.1 - 0.06 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) F-box PF00646.33 CDJ81854.1 - 4.9e-05 23.1 0.8 0.00014 21.6 0.8 1.7 1 0 0 1 1 1 1 F-box domain Luteo_PO PF04662.13 CDJ81854.1 - 0.04 13.6 0.1 0.073 12.7 0.1 1.3 1 0 0 1 1 1 0 Luteovirus P0 protein Patched PF02460.18 CDJ81855.1 - 4.8e-130 435.1 10.9 8.1e-130 434.4 10.9 1.3 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 CDJ81855.1 - 3.7e-33 114.5 5.7 3.7e-33 114.5 5.7 2.2 1 1 1 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 CDJ81855.1 - 2.2e-05 23.6 0.1 4.5e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 MMPL family PTP_tm PF18861.1 CDJ81855.1 - 0.02 14.9 2.4 0.34 10.9 0.7 2.4 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DOMON PF03351.17 CDJ81857.1 - 3.1e-13 50.0 0.0 5.3e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 CDJ81857.1 - 9.4e-08 32.3 11.3 2.4e-07 31.0 11.3 1.7 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 7TMR-DISM_7TM PF07695.11 CDJ81857.1 - 0.011 15.7 1.7 0.011 15.7 1.7 2.5 2 1 0 2 2 2 0 7TM diverse intracellular signalling Sulfotransfer_2 PF03567.14 CDJ81858.1 - 1.1e-22 81.1 2.8 1.5e-22 80.8 2.8 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sugar_tr PF00083.24 CDJ81859.1 - 2.1e-41 142.3 16.6 2.6e-41 141.9 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ81859.1 - 1.5e-18 66.9 16.6 1.5e-18 66.9 16.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CDJ81859.1 - 7.4e-05 21.4 0.5 7.4e-05 21.4 0.5 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 CDJ81859.1 - 0.00027 19.9 8.7 0.034 13.0 8.7 2.4 1 1 0 1 1 1 1 MFS_1 like family Imm17 PF15562.6 CDJ81859.1 - 6 6.8 9.9 0.96 9.4 0.1 3.6 4 0 0 4 4 4 0 Immunity protein 17 Rhodanese PF00581.20 CDJ81860.1 - 5.9e-24 84.6 0.0 2.7e-16 60.0 0.0 2.4 2 1 0 2 2 2 2 Rhodanese-like domain DUF4652 PF15525.6 CDJ81860.1 - 0.028 14.2 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) MtN3_slv PF03083.16 CDJ81861.1 - 0.0041 17.1 0.5 0.0041 17.1 0.5 2.5 2 1 0 3 3 3 1 Sugar efflux transporter for intercellular exchange DUF2569 PF10754.9 CDJ81861.1 - 0.14 12.6 7.3 0.054 13.9 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) DUF4315 PF14193.6 CDJ81862.1 - 0.024 14.7 0.4 0.042 13.9 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) DZR PF12773.7 CDJ81864.1 - 0.023 14.7 0.8 0.072 13.1 0.8 1.8 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 CDJ81864.1 - 0.059 13.1 0.1 0.19 11.5 0.1 1.9 1 0 0 1 1 1 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 CDJ81864.1 - 0.066 12.9 0.4 0.19 11.4 0.4 1.8 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.6 CDJ81864.1 - 0.094 12.2 0.8 0.39 10.2 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 CDJ81864.1 - 0.63 10.2 3.8 14 5.9 1.6 2.9 2 0 0 2 2 2 0 Zinc ribbon domain NOB1_Zn_bind PF08772.11 CDJ81865.1 - 0.019 15.1 0.5 0.12 12.6 0.5 2.2 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.7 CDJ81865.1 - 0.026 14.6 0.1 0.089 12.8 0.1 1.9 1 0 0 1 1 1 0 Double zinc ribbon zf-NADH-PPase PF09297.11 CDJ81865.1 - 0.062 13.0 0.2 0.14 11.8 0.2 1.6 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zf-C2H2_4 PF13894.6 CDJ81866.1 - 0.00042 20.9 24.2 0.039 14.8 2.1 5.2 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CDJ81866.1 - 0.025 15.3 6.7 0.24 12.1 3.2 2.7 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats FOXP-CC PF16159.5 CDJ81866.1 - 0.4 11.3 5.5 9.7 6.9 0.0 3.1 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_2 PF12756.7 CDJ81866.1 - 0.67 10.3 12.2 5.4 7.4 0.6 4.1 2 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 CDJ81866.1 - 0.78 10.3 0.1 0.78 10.3 0.1 4.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CDJ81866.1 - 1.1 9.6 4.2 3.5 8.0 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CDJ81867.1 - 0.0032 17.7 16.6 0.42 10.9 1.4 4.6 4 0 0 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 CDJ81867.1 - 0.071 12.9 0.5 0.071 12.9 0.5 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 CDJ81867.1 - 0.47 11.4 24.9 1.4 10.0 0.5 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CDJ81867.1 - 1.2 9.8 10.4 0.7 10.6 3.6 3.1 2 1 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats Zn-C2H2_12 PF18112.1 CDJ81867.1 - 7.8 7.1 7.9 0.86 10.1 0.2 2.9 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Globin PF00042.22 CDJ81868.1 - 0.0012 19.4 0.0 0.0017 18.9 0.0 1.3 1 0 0 1 1 1 1 Globin Pkinase_Tyr PF07714.17 CDJ81869.1 - 8.3e-84 280.9 0.0 1.4e-83 280.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.24 CDJ81869.1 - 5.1e-51 171.5 6.6 6.2e-25 87.5 0.4 2.4 2 0 0 2 2 2 2 Receptor L domain Pkinase PF00069.25 CDJ81869.1 - 2.6e-41 141.7 0.0 4.1e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.20 CDJ81869.1 - 1.8e-26 92.8 120.5 1.2e-23 83.6 39.1 5.2 2 1 3 5 5 5 2 Furin-like cysteine rich region GF_recep_IV PF14843.6 CDJ81869.1 - 5.7e-17 61.8 125.3 9.4e-14 51.3 31.6 6.1 3 2 3 6 6 6 4 Growth factor receptor domain IV Kinase-like PF14531.6 CDJ81869.1 - 0.0091 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CDJ81869.1 - 0.022 14.7 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDJ81869.1 - 0.031 13.2 0.3 0.056 12.4 0.3 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 CDJ81869.1 - 0.1 11.3 0.1 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 CDJ81869.1 - 0.14 11.7 0.2 0.31 10.6 0.2 1.5 1 0 0 1 1 1 0 RIO1 family FHA PF00498.26 CDJ81870.1 - 2.6e-12 46.9 1.5 1.4e-05 25.4 0.1 2.8 3 0 0 3 3 3 2 FHA domain zf-C3HC4 PF00097.25 CDJ81870.1 - 5.5e-06 26.2 15.7 1.4e-05 24.9 15.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ81870.1 - 2.7e-05 23.9 15.2 2.7e-05 23.9 15.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ81870.1 - 7.9e-05 22.9 16.1 7.9e-05 22.9 16.1 2.2 2 0 0 2 2 2 1 Ring finger domain Yop-YscD_cpl PF16697.5 CDJ81870.1 - 9.7e-05 22.6 0.0 0.44 10.9 0.0 2.9 3 0 0 3 3 3 2 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_3 PF13920.6 CDJ81870.1 - 0.0011 18.8 16.6 0.0029 17.4 16.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ81870.1 - 0.0036 17.4 16.5 0.0096 16.1 16.5 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 CDJ81870.1 - 0.0037 17.3 6.5 0.0079 16.2 6.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 CDJ81870.1 - 0.16 11.8 8.9 0.37 10.7 8.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 CDJ81870.1 - 0.56 10.1 8.9 1.3 8.9 8.9 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 CDJ81870.1 - 9.8 6.3 15.7 31 4.7 15.7 1.9 1 0 0 1 1 1 0 RING-type zinc-finger NDUF_B7 PF05676.13 CDJ81872.1 - 3.7e-25 87.4 2.1 4.9e-25 87.0 2.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 CDJ81872.1 - 0.012 15.6 2.6 0.019 15.0 2.6 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like WD40 PF00400.32 CDJ81873.1 - 2.8e-41 138.7 14.7 1.3e-06 29.0 0.4 11.5 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ81873.1 - 7.5e-19 67.8 0.2 0.0007 19.8 0.0 7.6 4 3 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDJ81873.1 - 5.3e-11 42.8 0.1 0.042 13.7 0.0 4.4 3 1 1 4 4 4 4 Eukaryotic translation initiation factor eIF2A DPPIV_N PF00930.21 CDJ81873.1 - 3.4e-05 22.8 0.4 5.7 5.6 0.0 4.6 4 1 1 5 5 5 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region Ge1_WD40 PF16529.5 CDJ81873.1 - 0.00021 20.4 0.6 3 6.7 0.0 4.4 3 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CDJ81873.1 - 0.0012 18.7 0.9 12 6.0 0.0 5.6 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.6 CDJ81873.1 - 0.013 15.6 0.0 0.59 10.2 0.0 2.9 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region TFIIIC_delta PF12657.7 CDJ81873.1 - 0.096 12.6 0.8 39 4.1 0.2 3.9 3 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Kelch_1 PF01344.25 CDJ81873.1 - 0.13 11.9 0.6 0.38 10.4 0.6 1.8 1 0 0 1 1 1 0 Kelch motif Proteasome_A_N PF10584.9 CDJ81873.1 - 0.17 11.6 0.1 2.1 8.1 0.1 2.7 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature DUF4064 PF13273.6 CDJ81874.1 - 0.0036 17.5 0.2 0.0047 17.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) STE2 PF02116.15 CDJ81874.1 - 0.046 13.0 0.2 0.06 12.7 0.2 1.0 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR FAM176 PF14851.6 CDJ81874.1 - 0.055 13.1 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 FAM176 family Myc_target_1 PF15179.6 CDJ81874.1 - 0.1 12.5 0.1 4.7 7.1 0.0 2.0 1 1 1 2 2 2 0 Myc target protein 1 Hum_adeno_E3A PF05393.11 CDJ81874.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein FeoB_associated PF12669.7 CDJ81874.1 - 0.24 11.8 0.2 0.4 11.1 0.2 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein SpoIIIAH PF12685.7 CDJ81876.1 - 0.089 12.6 0.3 0.089 12.6 0.3 2.4 2 1 0 2 2 2 0 SpoIIIAH-like protein DUF4834 PF16118.5 CDJ81876.1 - 0.15 13.0 0.1 0.15 13.0 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) MAP17 PF15807.5 CDJ81876.1 - 0.26 11.5 3.0 0.71 10.1 0.0 2.3 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4064 PF13273.6 CDJ81876.1 - 0.29 11.4 8.1 1.9 8.8 8.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) FAM176 PF14851.6 CDJ81876.1 - 0.64 9.7 6.1 0.73 9.5 0.0 2.3 2 0 0 2 2 2 0 FAM176 family Dicty_REP PF05086.12 CDJ81876.1 - 0.9 7.4 9.9 0.96 7.4 9.9 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Baculo_11_kDa PF06143.11 CDJ81876.1 - 1.4 8.6 3.1 3 7.5 3.1 1.7 1 1 0 1 1 1 0 Baculovirus 11 kDa family RIFIN PF02009.16 CDJ81876.1 - 8.9 6.1 15.6 3.4 7.5 12.9 1.7 1 1 1 2 2 2 0 Rifin Mucin PF01456.17 CDJ81879.1 - 0.078 13.0 16.4 0.12 12.4 16.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein FLYWCH PF04500.16 CDJ81881.1 - 9.4e-13 48.1 1.6 1.3e-12 47.7 1.6 1.2 1 0 0 1 1 1 1 FLYWCH zinc finger domain SRCR PF00530.18 CDJ81883.1 - 1.6e-17 63.8 0.9 3.8e-17 62.6 0.9 1.6 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Beta_helix PF13229.6 CDJ81883.1 - 1.7e-08 34.5 37.6 0.2 11.5 0.2 6.2 4 1 0 4 4 4 3 Right handed beta helix region MAP17 PF15807.5 CDJ81883.1 - 1.9e-05 24.9 0.0 3.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 SRCR_2 PF15494.6 CDJ81883.1 - 0.00055 20.4 0.4 0.00055 20.4 0.4 2.5 2 1 0 2 2 2 1 Scavenger receptor cysteine-rich domain Lectin_C PF00059.21 CDJ81883.1 - 0.0099 16.6 0.0 0.026 15.2 0.0 1.8 1 0 0 1 1 1 1 Lectin C-type domain Hepsin-SRCR PF09272.10 CDJ81883.1 - 0.01 16.4 0.1 0.028 14.9 0.1 1.7 1 0 0 1 1 1 0 Hepsin, SRCR domain TMEM51 PF15345.6 CDJ81883.1 - 0.011 15.6 0.5 0.026 14.4 0.2 1.7 1 1 0 1 1 1 0 Transmembrane protein 51 CYYR1 PF10873.8 CDJ81883.1 - 0.012 16.0 0.0 0.043 14.3 0.0 1.9 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 FixS PF03597.15 CDJ81883.1 - 0.72 9.6 4.9 1.4 8.7 4.9 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type MtN3_slv PF03083.16 CDJ81884.1 - 6.3e-18 64.6 11.9 3.9e-09 36.4 2.1 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange SKA1 PF07160.12 CDJ81885.1 - 2e-31 109.7 2.0 2e-31 109.7 2.0 1.6 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 1 DUF3161 PF11362.8 CDJ81885.1 - 0.036 14.1 0.8 0.14 12.2 0.0 2.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3161) TTR-52 PF01060.23 CDJ81888.1 - 1.3e-09 38.6 0.0 1.6e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 Transthyretin-like family Ribosomal_L28e PF01778.17 CDJ81889.1 - 4.2e-32 111.3 0.5 4.2e-32 111.3 0.5 2.2 3 0 0 3 3 3 1 Ribosomal L28e protein family Mak16 PF04874.14 CDJ81889.1 - 2e-28 98.9 14.7 2e-28 98.9 14.7 2.7 2 1 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 CDJ81889.1 - 5.3e-05 22.8 16.7 6.9e-05 22.4 16.7 1.1 1 0 0 1 1 1 1 BUD22 TLP-20 PF06088.11 CDJ81889.1 - 5.4 6.9 10.9 24 4.7 10.8 2.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Nucleo_P87 PF07267.11 CDJ81889.1 - 6.3 5.5 16.3 0.087 11.7 2.5 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 zf-C2H2_2 PF12756.7 CDJ81890.1 - 8.9e-32 109.4 13.9 1.9e-24 85.9 1.0 3.3 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CDJ81890.1 - 7.6e-12 45.2 7.3 3.1e-06 27.3 1.3 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDJ81890.1 - 1.6e-06 28.3 1.9 1.6e-06 28.3 1.9 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CDJ81890.1 - 0.0067 16.8 19.7 0.26 11.8 0.8 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-CpG_bind_C PF12269.8 CDJ81890.1 - 0.0099 15.7 2.3 0.0099 15.7 2.3 2.1 1 1 1 2 2 2 1 CpG binding protein zinc finger C terminal domain UPF0561 PF10573.9 CDJ81890.1 - 0.047 13.8 1.3 0.12 12.5 1.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 zf-C2H2_4 PF13894.6 CDJ81890.1 - 0.063 14.1 19.9 1.9 9.6 0.2 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger DUF1460 PF07313.12 CDJ81890.1 - 0.093 12.1 0.4 0.14 11.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) Nop25 PF09805.9 CDJ81890.1 - 0.51 10.8 8.7 0.032 14.7 3.3 1.7 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) zf_C2H2_ZHX PF18387.1 CDJ81890.1 - 1 9.1 6.4 13 5.5 0.2 3.3 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Pes-10 PF07149.11 CDJ81890.1 - 1.4 7.9 4.7 2.1 7.3 4.7 1.3 1 0 0 1 1 1 0 Pes-10 Astro_capsid_p PF12226.8 CDJ81890.1 - 2.4 7.2 7.1 3.5 6.7 7.1 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein HNH_5 PF14279.6 CDJ81890.1 - 9.9 6.1 10.3 9.3 6.2 0.1 3.7 4 0 0 4 4 4 0 HNH endonuclease FGF PF00167.18 CDJ81891.1 - 4.6e-40 136.6 0.1 7.6e-40 135.9 0.1 1.4 1 0 0 1 1 1 1 Fibroblast growth factor DUF1962 PF09227.10 CDJ81891.1 - 0.042 14.2 0.0 0.089 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1962) Clathrin_bdg PF15045.6 CDJ81892.1 - 0.028 14.4 0.1 0.039 14.0 0.1 1.4 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking YAcAr PF10686.9 CDJ81892.1 - 0.078 12.9 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family Ski_Sno PF02437.17 CDJ81893.1 - 1.7e-32 111.4 0.0 3.4e-32 110.4 0.0 1.5 1 0 0 1 1 1 1 SKI/SNO/DAC family Cofilin_ADF PF00241.20 CDJ81894.1 - 4.2e-28 97.6 0.1 8.7e-28 96.6 0.1 1.6 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Kelch_4 PF13418.6 CDJ81894.1 - 5.3e-09 35.9 0.3 0.0011 18.9 0.0 4.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CDJ81894.1 - 1.6e-08 34.0 6.7 0.075 12.6 0.1 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 CDJ81894.1 - 1.7e-08 34.5 1.4 0.0034 17.6 0.0 3.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ81894.1 - 8.1e-07 28.9 3.6 0.73 9.9 0.0 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 CDJ81894.1 - 5.5e-06 26.5 1.0 0.27 11.6 0.1 4.1 2 1 1 3 3 3 2 Kelch motif Kelch_2 PF07646.15 CDJ81894.1 - 0.038 14.0 6.6 2.6 8.2 0.1 3.8 4 0 0 4 4 4 0 Kelch motif HTH_48 PF17906.1 CDJ81895.1 - 7.3e-14 51.6 0.0 9e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 HTH domain in Mos1 transposase UNC-93 PF05978.16 CDJ81896.1 - 6.3e-47 159.2 8.4 1e-46 158.5 8.4 1.2 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 CDJ81896.1 - 3.4e-07 29.5 5.7 4.2e-07 29.2 5.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Shisa PF13908.6 CDJ81897.1 - 0.0081 16.4 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator An_peroxidase PF03098.15 CDJ81898.1 - 0 1125.9 0.2 6.6e-193 642.1 0.0 3.9 3 1 0 3 3 3 3 Animal haem peroxidase CLN3 PF02487.17 CDJ81899.1 - 4.8e-116 388.1 14.1 5.5e-116 387.9 14.1 1.0 1 0 0 1 1 1 1 CLN3 protein UPF0640 PF15114.6 CDJ81899.1 - 0.23 11.3 1.2 1.8 8.4 0.7 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0640 UDPGT PF00201.18 CDJ81900.1 - 4.1e-80 270.0 1.1 4.9e-80 269.7 1.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ81900.1 - 3.6e-09 36.8 0.0 7.1e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_4_4 PF13579.6 CDJ81900.1 - 0.00083 19.8 0.1 0.0068 16.9 0.1 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 CDJ81900.1 - 0.01 15.8 0.3 0.16 11.9 0.3 2.4 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Glyco_trans_1_3 PF13528.6 CDJ81900.1 - 0.016 14.4 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 1 Glyco_trans_4_2 PF13477.6 CDJ81900.1 - 0.021 14.8 0.0 0.052 13.6 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase 4-like Amnionless PF14828.6 CDJ81900.1 - 0.044 12.6 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 Amnionless UDPGT PF00201.18 CDJ81901.1 - 1.3e-67 228.7 0.7 1.6e-67 228.4 0.7 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ81901.1 - 7.1e-07 29.3 0.0 1.5e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_4_2 PF13477.6 CDJ81901.1 - 0.0051 16.9 0.1 0.021 14.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase 4-like DUF5010 PF16402.5 CDJ81901.1 - 0.021 13.7 0.0 0.15 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5010) Glyco_transf_4 PF13439.6 CDJ81901.1 - 0.089 12.8 0.0 0.39 10.7 0.0 2.1 1 1 0 1 1 1 0 Glycosyltransferase Family 4 DUF4440 PF14534.6 CDJ81902.1 - 7.9e-08 32.7 0.0 9.8e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) NTF2 PF02136.20 CDJ81902.1 - 0.0011 19.5 0.0 0.0013 19.3 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_3 PF13474.6 CDJ81902.1 - 0.0014 18.9 0.0 0.0017 18.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 CDJ81902.1 - 0.013 16.1 0.1 0.017 15.7 0.1 1.2 1 0 0 1 1 1 0 SnoaL-like domain DHFR_1 PF00186.19 CDJ81902.1 - 0.11 12.2 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Dihydrofolate reductase Ion_trans PF00520.31 CDJ81903.1 - 0.00021 20.6 8.5 0.00021 20.6 8.5 2.7 2 1 0 2 2 2 1 Ion transport protein Cnd1 PF12717.7 CDJ81903.1 - 0.11 12.6 0.1 0.38 10.8 0.0 1.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Pkinase PF00069.25 CDJ81904.1 - 2e-63 214.2 0.0 2.9e-63 213.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ81904.1 - 2.1e-36 125.6 0.0 3.3e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 CDJ81904.1 - 1.6e-33 114.4 25.9 4.5e-17 61.7 6.0 3.1 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 CDJ81904.1 - 1.1e-15 57.8 0.0 2e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.24 CDJ81904.1 - 1.4e-10 41.7 0.6 3.3e-10 40.5 0.6 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain C1_2 PF03107.16 CDJ81904.1 - 0.00019 21.7 17.5 0.032 14.6 2.7 3.2 3 0 0 3 3 3 2 C1 domain FYVE_2 PF02318.16 CDJ81904.1 - 0.00028 21.1 15.8 0.0072 16.5 1.8 2.8 2 1 1 3 3 3 2 FYVE-type zinc finger Kinase-like PF14531.6 CDJ81904.1 - 0.0071 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDJ81904.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Zf_RING PF16744.5 CDJ81904.1 - 0.043 13.9 16.2 0.048 13.8 2.5 2.9 3 0 0 3 3 3 0 KIAA1045 RING finger Haspin_kinase PF12330.8 CDJ81904.1 - 0.084 11.8 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain zf-RING_9 PF13901.6 CDJ81904.1 - 0.25 11.3 16.1 1.6 8.6 3.8 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon PHD_4 PF16866.5 CDJ81904.1 - 1.7 8.8 13.3 1 9.5 0.7 3.2 3 0 0 3 3 3 0 PHD-finger zf-ribbon_3 PF13248.6 CDJ81904.1 - 7.8 6.1 8.4 21 4.7 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain CCDC85 PF10226.9 CDJ81905.1 - 2.3e-43 148.1 18.9 5.9e-43 146.8 18.8 1.7 1 1 0 1 1 1 1 CCDC85 family Exonuc_VII_L PF02601.15 CDJ81905.1 - 0.0075 15.9 6.6 0.0075 15.9 6.6 2.2 1 1 0 2 2 2 1 Exonuclease VII, large subunit Shugoshin_N PF07558.11 CDJ81905.1 - 0.18 11.7 3.6 1 9.3 3.6 2.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region HALZ PF02183.18 CDJ81905.1 - 2.5 8.4 10.7 0.26 11.5 0.2 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper Clat_adaptor_s PF01217.20 CDJ81906.1 - 4.9e-58 195.1 4.8 5.6e-58 194.9 4.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF629 PF04780.12 CDJ81906.1 - 0.0026 16.4 0.8 0.0033 16.0 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF629) DDE_Tnp_IS66 PF03050.14 CDJ81906.1 - 0.079 12.4 0.2 0.13 11.7 0.1 1.4 2 0 0 2 2 2 0 Transposase IS66 family zf-C4 PF00105.18 CDJ81908.1 - 2.4e-17 63.2 13.3 4.8e-17 62.2 13.3 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ81908.1 - 3.9e-13 49.5 0.0 6.5e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DUF4874 PF16173.5 CDJ81909.1 - 0.017 14.8 0.7 2 8.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4874) Vac_Fusion PF02346.16 CDJ81909.1 - 0.044 13.4 1.2 0.93 9.2 0.4 2.7 1 1 1 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 Gly_acyl_tr_C PF08444.10 CDJ81909.1 - 0.081 13.2 0.2 0.75 10.1 0.1 2.2 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region DUF2605 PF10792.9 CDJ81909.1 - 0.19 11.6 1.7 8.7 6.3 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) Fib_alpha PF08702.10 CDJ81909.1 - 0.35 11.0 4.2 2.1 8.5 0.1 2.9 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Auto_anti-p27 PF06677.12 CDJ81911.1 - 4.1e-14 52.4 2.5 6.4e-14 51.8 2.5 1.3 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) BaffR-Tall_bind PF09256.10 CDJ81911.1 - 0.065 13.0 0.4 0.12 12.2 0.4 1.3 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding WD40 PF00400.32 CDJ81912.1 - 1.1e-08 35.5 0.1 0.0025 18.6 0.0 4.0 3 1 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ81912.1 - 0.00012 22.3 0.0 0.21 11.9 0.0 2.8 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ81912.1 - 0.086 11.8 0.1 3 6.7 0.0 2.3 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Methyltransf_16 PF10294.9 CDJ81913.1 - 4.9e-13 49.2 0.0 8.4e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 CDJ81913.1 - 4.2e-09 37.0 0.0 7.5e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ81913.1 - 1.9e-07 31.0 0.0 2.9e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ81913.1 - 2.3e-07 30.5 0.0 3.5e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 CDJ81913.1 - 5.6e-07 30.1 0.0 1.2e-06 29.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ81913.1 - 3.3e-06 27.0 0.0 5.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CDJ81913.1 - 1.2e-05 24.9 0.0 1.5e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 CDJ81913.1 - 0.00026 21.7 0.0 0.00044 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CDJ81913.1 - 0.00053 19.7 0.0 0.00086 19.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 TehB PF03848.14 CDJ81913.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB GRIP PF01465.20 CDJ81914.1 - 3.3e-11 42.9 0.0 7.7e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 GRIP domain Spc7 PF08317.11 CDJ81914.1 - 0.0021 17.0 20.6 0.0021 17.0 20.6 6.0 1 1 4 6 6 6 3 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 CDJ81914.1 - 0.0067 16.4 4.9 0.0067 16.4 4.9 9.9 3 2 5 9 9 9 1 TATA element modulatory factor 1 DNA binding Coat_F PF07875.12 CDJ81914.1 - 0.23 11.7 4.5 2 8.7 0.6 3.2 2 0 0 2 2 2 0 Coat F domain IKKbetaNEMObind PF12179.8 CDJ81914.1 - 0.36 10.9 4.9 2.7 8.1 0.2 3.8 3 0 0 3 3 3 0 I-kappa-kinase-beta NEMO binding domain zf-CCHC PF00098.23 CDJ81915.1 - 7.3e-07 29.0 1.9 1.6e-06 27.9 1.9 1.7 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 CDJ81915.1 - 0.008 16.7 0.0 0.026 15.1 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC_6 PF15288.6 CDJ81915.1 - 0.023 14.5 0.3 0.075 12.9 0.3 1.9 1 0 0 1 1 1 0 Zinc knuckle DUF629 PF04780.12 CDJ81916.1 - 0.0035 16.0 0.5 0.0053 15.3 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF629) CAP PF00188.26 CDJ81917.1 - 1.9e-17 64.3 4.4 2.8e-17 63.7 4.4 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PrmA PF06325.13 CDJ81919.1 - 1.1e-09 38.1 0.1 1.9e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CDJ81919.1 - 1.2e-08 35.5 0.0 2.5e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ81919.1 - 2.3e-07 31.4 0.0 5.4e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ81919.1 - 3.4e-05 23.5 0.1 5.6e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 CDJ81919.1 - 8.6e-05 22.4 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CDJ81919.1 - 0.0003 20.7 0.0 0.00052 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ81919.1 - 0.00076 20.2 0.0 0.0014 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ81919.1 - 0.001 18.9 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 CDJ81919.1 - 0.0035 17.1 0.4 0.029 14.1 0.0 2.1 2 0 0 2 2 2 1 Lysine methyltransferase PRMT5 PF05185.16 CDJ81919.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase DOT1 PF08123.13 CDJ81919.1 - 0.011 15.2 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_24 PF13578.6 CDJ81919.1 - 0.014 16.4 0.0 0.026 15.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 CDJ81919.1 - 0.021 14.5 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_9 PF08003.11 CDJ81919.1 - 0.021 13.8 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) CARDB PF07705.11 CDJ81919.1 - 0.035 14.4 0.0 0.095 13.0 0.0 1.7 1 0 0 1 1 1 0 CARDB Sugar_tr PF00083.24 CDJ81920.1 - 2.9e-63 214.3 27.1 3.4e-63 214.1 27.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ81920.1 - 1.4e-28 99.8 39.0 1.4e-28 99.8 39.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DHO_dh PF01180.21 CDJ81921.1 - 1e-93 313.8 0.0 1.2e-93 313.6 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 CDJ81921.1 - 0.011 14.8 0.3 0.33 9.9 0.4 2.6 2 1 0 2 2 2 0 FMN-dependent dehydrogenase NMO PF03060.15 CDJ81921.1 - 0.041 13.3 0.6 0.066 12.6 0.1 1.6 2 0 0 2 2 2 0 Nitronate monooxygenase PcrB PF01884.17 CDJ81921.1 - 0.091 12.2 0.1 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 PcrB family MFS_1 PF07690.16 CDJ81922.1 - 5.4e-14 51.9 41.4 6.8e-13 48.3 40.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ81922.1 - 3.4e-06 26.2 23.6 0.0047 15.9 9.7 3.2 3 1 0 3 3 3 2 Sugar (and other) transporter UCH PF00443.29 CDJ81923.1 - 5.8e-54 183.3 1.0 8.3e-54 182.8 0.2 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ81923.1 - 2.5e-17 63.5 1.8 1.6e-16 60.8 1.8 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.11 CDJ81923.1 - 1.1e-09 38.4 8.3 1.5e-09 38.0 5.7 2.2 2 0 0 2 2 2 1 USP8 dimerisation domain Spermine_synth PF01564.17 CDJ81925.1 - 1e-05 25.1 0.1 1.7e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_25 PF13649.6 CDJ81925.1 - 0.0045 17.7 0.0 0.0095 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ81925.1 - 0.037 13.6 0.0 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_17 PF12692.7 CDJ81925.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase Spermine_synth PF01564.17 CDJ81926.1 - 3.1e-66 222.4 0.0 6.4e-66 221.3 0.0 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CDJ81926.1 - 3.9e-22 77.9 0.1 3.3e-21 74.9 0.0 2.2 2 0 0 2 2 2 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 CDJ81926.1 - 0.00043 20.9 0.0 0.0018 18.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ81926.1 - 0.044 14.5 0.0 0.12 13.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CDJ81926.1 - 0.092 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain R3H-assoc PF13902.6 CDJ81927.1 - 1.7e-18 67.3 0.2 3.3e-18 66.3 0.1 1.5 1 1 0 1 1 1 1 R3H-associated N-terminal domain Thioredoxin_9 PF14595.6 CDJ81927.1 - 0.064 13.0 0.4 0.14 12.0 0.4 1.5 1 0 0 1 1 1 0 Thioredoxin Carn_acyltransf PF00755.20 CDJ81928.1 - 1.3e-187 625.0 0.1 1.6e-187 624.8 0.1 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CPT_N PF16484.5 CDJ81928.1 - 6.5e-22 77.3 0.1 1.5e-21 76.1 0.1 1.7 1 0 0 1 1 1 1 Carnitine O-palmitoyltransferase N-terminus 2OG-FeII_Oxy_2 PF13532.6 CDJ81928.1 - 1.2e-07 32.1 0.2 4.8e-07 30.2 0.2 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 CDJ81929.1 - 2e-22 79.8 0.0 2.4e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ81929.1 - 4.5e-10 39.2 0.0 5.7e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ81929.1 - 1.4e-09 37.3 0.0 1.7e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDJ81929.1 - 4.7e-08 33.3 0.0 0.0029 17.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 CDJ81929.1 - 0.0021 17.3 0.0 0.0031 16.8 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase Kdo PF06293.14 CDJ81929.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family rve PF00665.26 CDJ81931.1 - 0.0024 18.1 0.0 0.0028 17.8 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain SCVP PF17619.2 CDJ81932.1 - 0.0014 19.5 0.0 0.0018 19.1 0.0 1.3 1 0 0 1 1 1 1 Secreted clade V proteins CTD PF12815.7 CDJ81933.1 - 5.4e-06 26.9 19.7 0.026 15.1 3.0 3.3 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Ribosomal_L37e PF01907.19 CDJ81933.1 - 2.9 8.1 17.1 40 4.5 0.6 4.2 1 1 5 6 6 6 0 Ribosomal protein L37e Exo_endo_phos PF03372.23 CDJ81934.1 - 7.5e-06 25.6 0.0 7.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Hydrolase_2 PF07486.12 CDJ81934.1 - 0.12 13.3 0.3 0.24 12.2 0.3 1.5 1 0 0 1 1 1 0 Cell Wall Hydrolase RVT_1 PF00078.27 CDJ81935.1 - 2.2e-42 145.1 0.0 3e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDJ81936.1 - 4.6e-07 29.7 0.0 1.1e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Srg PF02118.21 CDJ81937.1 - 5.6e-10 39.3 10.5 6.6e-10 39.1 10.5 1.1 1 0 0 1 1 1 1 Srg family chemoreceptor 7TM_GPCR_Srv PF10323.9 CDJ81937.1 - 1.3e-09 37.9 9.8 1.6e-09 37.6 9.8 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Pex2_Pex12 PF04757.14 CDJ81938.1 - 3.1e-12 46.6 1.1 8.7e-12 45.1 1.1 1.6 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.25 CDJ81938.1 - 0.0019 18.0 3.1 0.0034 17.2 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 CDJ81938.1 - 0.0094 15.8 3.1 0.021 14.7 3.1 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 CDJ81938.1 - 0.01 15.8 4.7 0.018 15.0 4.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CDJ81938.1 - 0.016 15.1 4.8 0.028 14.3 4.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ81938.1 - 0.11 12.4 5.0 0.22 11.4 5.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ81938.1 - 0.61 10.2 3.4 1.5 8.9 3.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 CDJ81938.1 - 0.82 10.0 4.7 1.5 9.2 4.7 1.5 1 0 0 1 1 1 0 Ring finger domain G-patch PF01585.23 CDJ81939.1 - 8.2e-11 41.6 0.6 3.4e-10 39.6 0.6 2.1 2 0 0 2 2 2 1 G-patch domain RRM_1 PF00076.22 CDJ81939.1 - 4.4e-06 26.4 0.1 8.2e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tudor_3 PF18115.1 CDJ81941.1 - 0.096 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain CDC45 PF02724.14 CDJ81941.1 - 0.15 10.3 5.3 0.25 9.6 5.3 1.2 1 0 0 1 1 1 0 CDC45-like protein RVT_1 PF00078.27 CDJ81943.1 - 7.8e-08 32.1 0.0 1.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDJ81944.1 - 0.00025 20.9 0.0 0.00061 19.6 0.0 1.6 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Peptidase_C48 PF02902.19 CDJ81945.1 - 0.0002 21.3 0.0 0.00026 20.9 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Glyco_transf_10 PF00852.19 CDJ81946.1 - 4.8e-47 160.0 1.5 7.2e-47 159.4 1.5 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CDJ81946.1 - 1.2e-16 61.1 1.7 1.9e-16 60.5 0.2 2.1 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal DUF998 PF06197.13 CDJ81946.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Glyco_transf_10 PF00852.19 CDJ81947.1 - 3e-46 157.3 0.3 4.3e-46 156.9 0.3 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CDJ81947.1 - 9.4e-17 61.5 0.1 1.1e-15 58.0 0.0 2.3 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Recep_L_domain PF01030.24 CDJ81948.1 - 6.1e-36 123.0 14.5 1.1e-07 31.9 0.2 6.8 6 2 1 7 7 7 5 Receptor L domain Utp21 PF04192.12 CDJ81948.1 - 0.048 13.2 0.2 0.083 12.4 0.2 1.3 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain Pyridoxal_deC PF00282.19 CDJ81949.1 - 2.1e-35 122.2 0.0 2.7e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain TMEM51 PF15345.6 CDJ81949.1 - 0.059 13.2 0.3 0.09 12.6 0.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Ly49 PF08391.10 CDJ81949.1 - 0.062 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region SieB PF14163.6 CDJ81949.1 - 0.07 12.6 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Super-infection exclusion protein B T2SSM PF04612.12 CDJ81949.1 - 0.13 12.3 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M DUF2207 PF09972.9 CDJ81949.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CcmD PF04995.14 CDJ81949.1 - 0.27 11.3 4.5 0.59 10.3 4.5 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Pyridoxal_deC PF00282.19 CDJ81950.1 - 1.6e-16 60.0 0.2 2.3e-16 59.5 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain gag-asp_proteas PF13975.6 CDJ81954.1 - 8.7e-05 23.0 0.0 0.00018 22.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ81954.1 - 0.076 13.7 0.0 0.18 12.4 0.0 1.7 1 1 0 1 1 1 0 Aspartyl protease TcpQ PF10671.9 CDJ81955.1 - 0.019 15.1 0.2 0.047 13.8 0.2 1.6 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q DUF1758 PF05585.12 CDJ81956.1 - 1.8e-10 40.8 0.0 3.8e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 CDJ81956.1 - 9.2e-05 23.0 0.0 0.00026 21.6 0.0 1.8 1 1 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 CDJ81956.1 - 0.00019 21.0 0.1 0.00054 19.5 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CDJ81956.1 - 0.0004 20.9 0.0 0.0011 19.5 0.0 1.7 1 1 1 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ81956.1 - 0.0038 17.0 0.0 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 CDJ81956.1 - 0.18 12.1 0.1 0.77 10.1 0.0 2.0 1 1 1 2 2 2 0 Retroviral aspartyl protease Phage_GPO PF05929.11 CDJ81957.1 - 0.013 15.2 2.0 0.022 14.4 2.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase phiKZ_IP PF12699.7 CDJ81957.1 - 0.033 13.3 0.2 0.066 12.3 0.2 1.5 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins YojJ PF10372.9 CDJ81957.1 - 0.27 11.3 5.6 0.24 11.5 2.6 2.5 2 1 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus ABC_tran_CTD PF16326.5 CDJ81957.1 - 0.32 11.3 5.0 6.9 7.0 2.2 2.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain GPW_gp25 PF04965.14 CDJ81957.1 - 0.35 10.7 2.5 0.61 9.9 0.7 2.3 2 0 0 2 2 2 0 Gene 25-like lysozyme Vac_Fusion PF02346.16 CDJ81957.1 - 5.9 6.6 7.0 7.5 6.3 0.3 3.4 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 Allexi_40kDa PF05549.11 CDJ81957.1 - 8.1 5.9 7.7 5.6 6.4 3.4 2.4 2 1 0 2 2 2 0 Allexivirus 40kDa protein ABC_tran PF00005.27 CDJ81958.1 - 0.0024 18.4 0.0 0.0034 17.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 CDJ81958.1 - 0.024 14.5 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 CDJ81958.1 - 0.093 13.2 0.2 0.26 11.7 0.1 1.7 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.22 CDJ81958.1 - 0.12 11.6 0.0 0.24 10.6 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 CDJ81958.1 - 0.13 12.1 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RT_RNaseH_2 PF17919.1 CDJ81960.1 - 9.1e-30 102.7 0.0 1.2e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ81960.1 - 6.4e-24 84.3 0.0 7.5e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Herpes_pp85 PF04637.12 CDJ81961.1 - 0.56 8.6 1.6 0.71 8.2 1.6 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Hormone_recep PF00104.30 CDJ81962.1 - 2.8e-10 40.1 0.1 3.3e-10 39.9 0.1 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Glyco_transf_22 PF03901.17 CDJ81963.1 - 4.5e-63 213.9 28.5 4.5e-63 213.9 28.5 1.4 2 0 0 2 2 2 1 Alg9-like mannosyltransferase family tRNA-synt_1 PF00133.22 CDJ81964.1 - 2e-155 518.4 0.0 7.3e-154 513.3 0.0 2.6 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDJ81964.1 - 8.8e-25 87.4 0.3 2.1e-24 86.2 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CDJ81964.1 - 3.7e-13 49.0 0.2 1.1e-05 24.5 0.1 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CDJ81964.1 - 5.5e-05 22.7 0.1 0.0016 18.0 0.0 2.6 2 1 1 3 3 3 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1f PF01921.18 CDJ81964.1 - 0.019 13.9 0.0 3.7 6.4 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (K) tRNA-synt_1b PF00579.25 CDJ81964.1 - 0.15 11.3 0.6 0.52 9.6 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) EGL-1 PF11430.8 CDJ81969.1 - 0.062 13.2 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Programmed cell death activator EGL-1 MH2 PF03166.14 CDJ81970.1 - 2.1e-61 207.4 0.3 3.3e-61 206.8 0.3 1.3 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 CDJ81970.1 - 2.5e-39 133.6 4.6 3.7e-39 133.1 1.9 2.2 2 0 0 2 2 2 1 MH1 domain CLASP_N PF12348.8 CDJ81971.1 - 6.9e-32 110.8 1.6 6.9e-32 110.8 1.6 3.2 3 0 0 3 3 3 1 CLASP N terminal DUF5071 PF16804.5 CDJ81971.1 - 0.00049 20.3 0.4 0.16 12.2 0.0 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF5071) MMS19_N PF14500.6 CDJ81971.1 - 0.0016 18.1 4.8 0.91 9.0 0.2 4.5 5 1 0 5 5 5 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT PF02985.22 CDJ81971.1 - 0.0032 17.6 8.2 0.98 9.9 0.0 5.6 6 0 0 6 6 5 2 HEAT repeat TAN PF11640.8 CDJ81971.1 - 0.0048 17.0 2.6 0.01 16.0 0.1 2.9 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair Tti2 PF10521.9 CDJ81971.1 - 0.013 15.1 1.7 0.74 9.3 0.2 3.0 3 0 0 3 3 3 0 Tti2 family RTP1_C1 PF10363.9 CDJ81971.1 - 0.018 15.2 1.5 8.9 6.5 0.0 4.6 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 GEP5 PF17053.5 CDJ81971.1 - 0.094 12.5 2.7 0.21 11.4 0.1 2.7 3 0 0 3 3 3 0 Genetic interactor of prohibitin 5 V-ATPase_H_N PF03224.14 CDJ81971.1 - 0.18 11.0 3.9 0.31 10.3 1.5 2.4 2 0 0 2 2 2 0 V-ATPase subunit H DUF2785 PF10978.8 CDJ81971.1 - 0.24 11.2 1.5 11 5.7 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2785) Cnd1 PF12717.7 CDJ81971.1 - 2.6 8.1 6.3 1.1e+02 2.8 0.0 4.5 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 BUD22 PF09073.10 CDJ81972.1 - 0.0016 17.9 7.9 0.0021 17.5 7.9 1.0 1 0 0 1 1 1 1 BUD22 PBP1_TM PF14812.6 CDJ81972.1 - 5.4 7.5 11.3 19 5.7 11.3 2.0 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_C97 PF05903.14 CDJ81973.1 - 2.4e-40 137.8 0.0 2.8e-40 137.6 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain DM PF00751.18 CDJ81974.1 - 1.3e-06 28.2 2.5 1.3e-06 28.2 2.5 1.7 2 0 0 2 2 2 1 DM DNA binding domain BRO1 PF03097.18 CDJ81975.1 - 7.3e-29 100.8 0.0 1e-28 100.3 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain Kunitz_BPTI PF00014.23 CDJ81977.1 - 9.2e-100 326.8 55.5 9.1e-18 64.3 3.8 7.4 7 0 0 7 7 7 7 Kunitz/Bovine pancreatic trypsin inhibitor domain Ldl_recept_a PF00057.18 CDJ81978.1 - 6.7e-15 55.0 27.3 2.2e-08 34.2 9.7 2.3 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A CytochromB561_N PF09786.9 CDJ81978.1 - 0.26 10.3 6.7 0.3 10.0 6.7 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Oxygenase-NA PF09859.9 CDJ81981.1 - 0.18 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA Homeodomain PF00046.29 CDJ81982.1 - 1.8e-19 69.3 6.8 2.9e-19 68.6 6.8 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ81982.1 - 0.00019 21.3 0.1 0.00048 20.0 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain QLQ PF08880.11 CDJ81982.1 - 0.026 14.3 2.0 0.068 12.9 2.0 1.7 1 0 0 1 1 1 0 QLQ Homez PF11569.8 CDJ81982.1 - 0.08 12.4 0.3 0.15 11.5 0.3 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Rbsn PF11464.8 CDJ81983.1 - 0.0051 16.5 0.2 0.01 15.5 0.2 1.5 1 0 0 1 1 1 1 Rabenosyn Rab binding domain PRCC PF10253.9 CDJ81983.1 - 0.023 15.5 1.1 0.028 15.2 1.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Med9 PF07544.13 CDJ81983.1 - 0.035 14.2 2.7 0.058 13.5 2.7 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF896 PF05979.12 CDJ81983.1 - 0.076 12.9 0.5 0.13 12.2 0.5 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) BIR PF00653.21 CDJ81985.1 - 4.4e-18 65.7 4.1 7.5e-18 65.0 4.1 1.4 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain BTB PF00651.31 CDJ81986.1 - 3.3e-06 27.3 0.0 8.1e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Fer4_6 PF12837.7 CDJ81986.1 - 3 8.1 11.8 5.9 7.1 2.4 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain DHOase PF12890.7 CDJ81987.1 - 0.029 14.3 0.0 0.03 14.3 0.0 1.1 1 0 0 1 1 1 0 Dihydro-orotase-like GTP_cyclohydroI PF01227.22 CDJ81988.1 - 1.3e-75 252.8 0.5 1.5e-75 252.5 0.5 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 CDJ81988.1 - 9.8e-06 25.6 0.0 3.8e-05 23.8 0.0 2.0 1 1 1 2 2 2 1 QueF-like protein DUF1706 PF08020.11 CDJ81989.1 - 0.027 14.4 0.8 0.3 11.0 0.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1706) Ammonium_transp PF00909.21 CDJ81991.1 - 7e-83 278.5 19.9 8.9e-83 278.2 19.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Keratin_2_head PF16208.5 CDJ81993.1 - 3.6 7.7 20.8 3.7 7.7 20.8 1.0 1 0 0 1 1 1 0 Keratin type II head FAM110_C PF14160.6 CDJ81995.1 - 1.5e-06 29.2 0.4 3.9e-06 27.9 0.3 1.8 1 1 0 1 1 1 1 Centrosome-associated C terminus DUF4490 PF14892.6 CDJ81997.1 - 0.089 12.9 0.6 0.5 10.4 0.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4490) TAF PF02969.17 CDJ81997.1 - 0.79 9.9 3.8 1.2 9.4 0.9 2.3 1 1 1 2 2 2 0 TATA box binding protein associated factor (TAF) ADK PF00406.22 CDJ81998.1 - 1.6e-05 25.0 0.0 3.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CDJ81998.1 - 0.00012 22.5 0.0 0.00041 20.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain CPG4 PF15481.6 CDJ82000.1 - 1.7e-18 67.0 9.4 1.7e-18 67.0 9.4 2.3 2 1 0 2 2 2 1 Chondroitin proteoglycan 4 Pkinase PF00069.25 CDJ82001.1 - 9.4e-77 257.9 0.0 1.1e-76 257.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ82001.1 - 3.4e-36 124.9 0.0 4.5e-36 124.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ82001.1 - 7.9e-07 28.3 0.0 1.5e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CDJ82001.1 - 0.0001 22.3 0.3 0.00024 21.1 0.4 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CDJ82001.1 - 0.0013 18.1 0.2 0.0025 17.2 0.2 1.7 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 CDJ82001.1 - 0.017 14.2 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Lectin_C PF00059.21 CDJ82002.1 - 1.6e-28 99.5 1.4 4.7e-14 53.0 0.3 2.5 2 0 0 2 2 2 2 Lectin C-type domain CUB PF00431.20 CDJ82002.1 - 3.9e-27 94.8 0.2 4.1e-17 62.5 0.0 2.4 2 0 0 2 2 2 2 CUB domain UL45 PF05473.12 CDJ82002.1 - 0.00088 19.0 1.8 0.0067 16.1 0.1 2.4 2 0 0 2 2 2 1 UL45 protein, carbohydrate-binding C-type lectin-like COE1_DBD PF16422.5 CDJ82002.1 - 0.073 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Transcription factor COE1 DNA-binding domain MCM_bind PF09739.9 CDJ82003.1 - 6.6e-68 229.6 0.1 3.3e-60 204.2 0.0 2.5 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor HTH_48 PF17906.1 CDJ82004.1 - 9.6e-12 44.8 0.1 1.5e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 CDJ82004.1 - 0.00012 22.6 0.6 0.00037 21.1 0.2 2.0 1 1 1 2 2 2 1 Homeodomain-like domain Transposase_1 PF01359.18 CDJ82004.1 - 0.00015 21.5 2.8 0.00022 21.0 0.0 2.4 3 0 0 3 3 3 1 Transposase (partial DDE domain) HTH_Tnp_Tc3_2 PF01498.18 CDJ82004.1 - 0.0028 17.8 0.1 0.0054 17.0 0.1 1.4 1 0 0 1 1 1 1 Transposase HTH_24 PF13412.6 CDJ82004.1 - 0.0039 16.7 0.0 0.0081 15.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 CDJ82004.1 - 0.0072 16.3 0.1 0.014 15.4 0.1 1.4 1 0 0 1 1 1 1 HTH domain HTH_AsnC-type PF13404.6 CDJ82004.1 - 0.012 15.4 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain GerE PF00196.19 CDJ82004.1 - 0.033 13.7 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_Tnp_IS630 PF01710.16 CDJ82004.1 - 0.044 13.8 0.1 0.06 13.4 0.1 1.3 1 0 0 1 1 1 0 Transposase FH2 PF02181.23 CDJ82005.1 - 0.011 14.9 5.4 0.15 11.1 0.1 2.3 1 1 1 2 2 2 0 Formin Homology 2 Domain YlbD_coat PF14071.6 CDJ82005.1 - 0.38 11.0 6.4 0.093 13.0 0.5 2.5 2 1 1 3 3 3 0 Putative coat protein LMBR1 PF04791.16 CDJ82005.1 - 4 6.2 9.9 5.3 5.8 9.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Syntaxin PF00804.25 CDJ82005.1 - 4.1 7.0 20.5 0.31 10.7 5.5 2.3 1 1 0 2 2 2 0 Syntaxin DUF724 PF05266.14 CDJ82005.1 - 5 6.9 18.3 0.25 11.1 2.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF724) ADIP PF11559.8 CDJ82005.1 - 8.4 6.5 18.8 0.27 11.3 6.6 2.5 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding rve PF00665.26 CDJ82006.1 - 1.1e-10 41.7 0.0 1.5e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DUF1759 PF03564.15 CDJ82007.1 - 6.7e-21 74.8 1.5 1.4e-20 73.7 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) Peptidase_A17 PF05380.13 CDJ82007.1 - 5.9e-05 23.1 0.1 0.00011 22.2 0.1 1.5 1 0 0 1 1 1 1 Pao retrotransposon peptidase Ly-6_related PF06579.12 CDJ82008.1 - 4.8e-06 26.8 0.9 6.3e-06 26.5 0.6 1.4 1 1 0 1 1 1 1 Caenorhabditis elegans ly-6-related protein QVR PF17064.5 CDJ82008.1 - 0.55 10.5 6.0 15 5.9 6.0 2.2 1 1 0 1 1 1 0 Sleepless protein Innexin PF00876.18 CDJ82009.1 - 6.4e-109 364.4 15.3 7.7e-109 364.2 15.3 1.1 1 0 0 1 1 1 1 Innexin WAP PF00095.21 CDJ82010.1 - 1.6e-05 25.2 10.0 2.2e-05 24.7 10.0 1.2 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' WAP PF00095.21 CDJ82011.1 - 0.0004 20.7 37.2 0.0017 18.7 12.3 3.4 3 0 0 3 3 3 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' DUF5326 PF17260.2 CDJ82012.1 - 0.44 10.7 1.9 0.36 11.0 0.4 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5326) Phospholip_A2_1 PF00068.19 CDJ82012.1 - 9.2 6.8 20.4 29 5.2 0.3 3.3 2 1 0 2 2 2 0 Phospholipase A2 zf-H2C2_5 PF13909.6 CDJ82014.1 - 4.5e-08 32.7 5.0 0.0004 20.1 0.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_12 PF18658.1 CDJ82014.1 - 0.03 13.9 3.3 10 5.8 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger C2H2-type zf-RING_7 PF02591.15 CDJ82014.1 - 0.26 11.5 0.0 0.26 11.5 0.0 2.6 4 0 0 4 4 4 0 C4-type zinc ribbon domain zf-BED PF02892.15 CDJ82014.1 - 0.28 11.2 0.1 0.28 11.2 0.1 3.2 3 0 0 3 3 3 0 BED zinc finger zf-MYST PF17772.1 CDJ82014.1 - 1.3 8.7 4.7 1.5 8.5 0.2 2.6 2 0 0 2 2 2 0 MYST family zinc finger domain zf-C2H2_4 PF13894.6 CDJ82014.1 - 1.7 9.7 20.3 1.4 9.9 1.2 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger AAA PF00004.29 CDJ82015.1 - 4.4e-45 153.3 0.0 1.1e-40 139.1 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 CDJ82015.1 - 1.1e-16 60.6 0.1 2.3e-16 59.6 0.1 1.5 1 0 0 1 1 1 1 Bromodomain AAA_lid_3 PF17862.1 CDJ82015.1 - 7.8e-10 38.4 0.0 2.8e-09 36.6 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain IstB_IS21 PF01695.17 CDJ82015.1 - 2.1e-06 27.6 0.0 4.6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 CDJ82015.1 - 2.2e-05 24.6 0.0 6.1e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CDJ82015.1 - 9.2e-05 22.9 0.0 0.00092 19.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 CDJ82015.1 - 0.0027 18.1 0.0 0.0065 16.8 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.14 CDJ82015.1 - 0.003 17.5 0.0 0.013 15.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 CDJ82015.1 - 0.011 16.0 0.5 0.11 12.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 CDJ82015.1 - 0.016 15.5 0.1 0.19 12.0 0.1 2.8 2 1 0 2 2 1 0 AAA domain RuvB_N PF05496.12 CDJ82015.1 - 0.022 14.5 0.0 0.059 13.1 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 CDJ82015.1 - 0.066 12.9 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CDJ82015.1 - 0.072 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_18 PF13238.6 CDJ82015.1 - 0.082 13.4 0.0 0.082 13.4 0.0 2.7 3 0 0 3 3 1 0 AAA domain Mg_chelatase PF01078.21 CDJ82015.1 - 0.084 12.2 0.1 0.24 10.8 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 CDJ82015.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain ABC_tran PF00005.27 CDJ82015.1 - 0.14 12.7 0.1 1.4 9.4 0.0 2.6 2 0 0 2 2 2 0 ABC transporter ResIII PF04851.15 CDJ82015.1 - 0.15 12.1 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 CDJ82015.1 - 0.16 11.5 0.0 0.38 10.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 CDJ82015.1 - 0.37 10.9 0.0 0.37 10.9 0.0 3.6 4 0 0 4 4 3 0 AAA domain UCH PF00443.29 CDJ82016.1 - 2.5e-59 200.8 2.0 4.8e-59 199.9 2.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ82016.1 - 2.8e-27 96.2 5.4 2.8e-27 96.2 5.4 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase FHA PF00498.26 CDJ82016.1 - 4.6e-17 62.1 0.0 1.7e-16 60.3 0.0 2.1 2 0 0 2 2 2 1 FHA domain dsrm PF00035.26 CDJ82016.1 - 3.3e-10 40.5 0.2 1.8e-08 35.0 0.1 2.7 2 0 0 2 2 2 1 Double-stranded RNA binding motif Yop-YscD_cpl PF16697.5 CDJ82016.1 - 2.9e-07 30.7 0.0 1.2e-06 28.7 0.0 2.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Dicer_dimer PF03368.14 CDJ82016.1 - 8.2e-05 22.7 0.2 0.00042 20.4 0.0 2.3 3 0 0 3 3 3 1 Dicer dimerisation domain Occludin_ELL PF07303.13 CDJ82016.1 - 0.33 11.7 5.0 0.21 12.3 1.3 2.6 2 0 0 2 2 2 0 Occludin homology domain Ndc1_Nup PF09531.10 CDJ82016.1 - 0.99 8.0 4.5 1.5 7.4 4.5 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_C98 PF15499.6 CDJ82016.1 - 4.3 6.7 15.3 0.5 9.8 7.8 3.0 3 1 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase ECH_2 PF16113.5 CDJ82017.1 - 1.2e-133 445.8 0.0 1.3e-133 445.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CDJ82017.1 - 9.6e-30 103.7 0.1 2.1e-27 96.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Myosin_head PF00063.21 CDJ82018.1 - 1.5e-247 823.2 0.8 1.9e-247 822.9 0.8 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 CDJ82018.1 - 1.5e-33 116.0 0.0 3.3e-33 114.9 0.0 1.6 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding AAA_22 PF13401.6 CDJ82018.1 - 0.017 15.4 0.0 0.084 13.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CDJ82018.1 - 0.04 14.3 0.0 0.22 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain IQ PF00612.27 CDJ82018.1 - 3.3 7.8 6.8 0.23 11.3 1.3 2.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif ATP-synt_C PF00137.21 CDJ82019.1 - 4.3e-36 123.1 35.9 6.4e-22 77.7 13.2 2.0 2 0 0 2 2 2 2 ATP synthase subunit C SH PF01445.17 CDJ82019.1 - 0.22 11.5 1.0 0.61 10.1 0.2 1.9 2 0 0 2 2 2 0 Viral small hydrophobic protein DUF2970 PF11174.8 CDJ82019.1 - 4.1 7.3 8.0 1.2 9.1 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Cullin PF00888.22 CDJ82020.1 - 3.4e-193 643.6 16.5 4.2e-193 643.3 16.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CDJ82020.1 - 3.6e-28 97.4 2.2 1.1e-27 95.8 2.2 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain DNA_pol3_gamma3 PF12169.8 CDJ82020.1 - 0.055 13.4 1.4 0.29 11.1 0.0 2.9 4 0 0 4 4 4 0 DNA polymerase III subunits gamma and tau domain III DUF2063 PF09836.9 CDJ82020.1 - 0.066 13.5 0.1 2.2 8.6 0.0 2.9 2 0 0 2 2 2 0 Putative DNA-binding domain Tau95 PF09734.9 CDJ82020.1 - 0.25 12.1 4.8 9.2 7.1 0.0 3.3 3 1 0 3 3 3 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain SecA_SW PF07516.13 CDJ82020.1 - 7.2 6.6 14.1 0.054 13.5 1.1 3.2 2 1 1 3 3 3 0 SecA Wing and Scaffold domain Ribosomal_L6e PF01159.19 CDJ82021.1 - 3.7e-35 120.8 0.1 6.2e-35 120.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 CDJ82021.1 - 0.00058 20.1 0.0 0.0021 18.3 0.0 1.9 1 0 0 1 1 1 1 Ribosomal protein L6, N-terminal domain ResIII PF04851.15 CDJ82022.1 - 1e-13 51.7 0.0 1.4e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ82022.1 - 3e-13 49.9 0.0 4.3e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 CDJ82022.1 - 0.11 11.7 0.2 0.22 10.7 0.2 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ASC PF00858.24 CDJ82023.1 - 1.9e-120 402.8 8.3 2.8e-120 402.3 8.3 1.3 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel DUF1198 PF06711.11 CDJ82025.1 - 0.13 12.3 0.3 16 5.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1198) DUF3760 PF12586.8 CDJ82025.1 - 0.14 12.4 0.2 0.28 11.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) Ras PF00071.22 CDJ82026.1 - 1.1e-10 41.4 0.1 5.9e-09 35.7 0.0 2.2 2 0 0 2 2 2 1 Ras family zf-C3HC4 PF00097.25 CDJ82026.1 - 1.4e-10 40.9 11.7 2.9e-10 39.9 11.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ82026.1 - 4.8e-10 39.3 6.9 1.1e-09 38.1 6.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDJ82026.1 - 1.3e-09 37.7 14.0 2.7e-09 36.7 14.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ82026.1 - 1.1e-08 35.2 15.0 2.5e-08 34.1 15.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDJ82026.1 - 1.7e-08 34.2 11.1 3.7e-08 33.1 11.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ82026.1 - 2.3e-08 34.1 10.6 5.2e-08 32.9 10.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CDJ82026.1 - 1e-06 28.6 13.3 2.3e-06 27.5 13.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain U-box PF04564.15 CDJ82026.1 - 3.9e-06 26.9 0.0 8.3e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-rbx1 PF12678.7 CDJ82026.1 - 2.8e-05 24.3 11.3 9.3e-05 22.6 11.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CDJ82026.1 - 5.4e-05 23.0 9.9 0.00012 21.9 9.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 CDJ82026.1 - 0.0014 18.4 6.1 0.0036 17.1 6.1 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein AAA_16 PF13191.6 CDJ82026.1 - 0.0026 18.2 0.0 0.0069 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Sec66 PF09802.9 CDJ82026.1 - 0.039 13.5 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 AAA_22 PF13401.6 CDJ82026.1 - 0.051 13.9 0.2 3.2 8.0 0.1 3.1 2 1 0 2 2 2 0 AAA domain zf-RING_4 PF14570.6 CDJ82026.1 - 0.087 12.6 9.6 0.21 11.4 9.6 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Roc PF08477.13 CDJ82026.1 - 0.097 12.9 0.2 2.4 8.4 0.2 2.4 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase zf-ANAPC11 PF12861.7 CDJ82026.1 - 0.12 12.4 4.7 0.32 11.1 4.7 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 CDJ82026.1 - 0.58 9.9 7.3 1.6 8.5 7.3 1.8 1 0 0 1 1 1 0 RING-like zinc finger DpnI PF06044.12 CDJ82026.1 - 0.76 9.4 2.6 0.58 9.8 0.4 1.9 2 0 0 2 2 2 0 Dam-replacing family zf-RING_10 PF16685.5 CDJ82026.1 - 0.91 9.7 11.0 0.084 13.0 5.9 1.9 2 0 0 2 2 2 0 zinc RING finger of MSL2 DUF1041 PF06292.17 CDJ82027.1 - 3.3e-24 85.3 0.7 1.2e-23 83.5 0.7 2.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1041) PH PF00169.29 CDJ82027.1 - 2.8e-05 24.6 0.5 8.4e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 PH domain C2 PF00168.30 CDJ82027.1 - 0.00019 21.7 0.2 0.0011 19.2 0.1 2.3 2 0 0 2 2 2 1 C2 domain DUF1217 PF06748.12 CDJ82027.1 - 0.0044 17.1 0.1 0.0097 16.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1217) CAP PF00188.26 CDJ82028.1 - 2.6e-33 115.6 14.4 1.7e-17 64.5 0.9 2.3 2 0 0 2 2 2 2 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ82028.1 - 0.0002 21.6 3.3 0.13 12.5 0.1 2.7 2 1 0 2 2 2 2 Ancylostoma-associated secreted protein related ATP-synt_F6 PF05511.11 CDJ82028.1 - 0.15 12.5 0.0 9.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 Metallothio_Euk PF12749.7 CDJ82028.1 - 0.15 12.2 19.8 1.4 9.1 5.3 2.7 2 0 0 2 2 2 0 Eukaryotic metallothionein Metallothio PF00131.20 CDJ82028.1 - 0.78 9.9 22.4 2.4 8.4 6.5 3.2 2 0 0 2 2 2 0 Metallothionein Metallothio_PEC PF02068.16 CDJ82028.1 - 1 9.7 23.6 1.3 9.5 9.7 2.7 2 0 0 2 2 2 0 Plant PEC family metallothionein DUF4373 PF14297.6 CDJ82029.1 - 0.15 12.8 0.0 0.22 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4373) PH PF00169.29 CDJ82031.1 - 9.5e-10 38.9 0.6 2.3e-09 37.7 0.6 1.7 1 0 0 1 1 1 1 PH domain Serpin PF00079.20 CDJ82032.1 - 3.3e-91 306.4 4.7 3.8e-91 306.2 4.7 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Ferritin-like PF12902.7 CDJ82032.1 - 0.027 14.4 0.7 0.058 13.3 0.7 1.5 1 0 0 1 1 1 0 Ferritin-like Glycos_transf_2 PF00535.26 CDJ82033.1 - 2.8e-24 85.8 0.0 3.4e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CDJ82033.1 - 5.8e-09 36.2 0.0 1.2e-08 35.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CDJ82033.1 - 5.2e-05 22.9 0.0 6.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 CDJ82033.1 - 0.032 14.7 0.0 0.063 13.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 RNA_pol_A_bac PF01000.26 CDJ82034.1 - 6e-28 97.5 0.0 1.3e-27 96.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CDJ82034.1 - 1e-19 69.7 0.0 1.7e-19 69.0 0.0 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain OPA3 PF07047.12 CDJ82035.1 - 1.3e-19 70.2 0.1 1.3e-19 70.2 0.1 1.6 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) Striatin PF08232.12 CDJ82035.1 - 0.012 16.2 0.6 0.018 15.6 0.6 1.2 1 0 0 1 1 1 0 Striatin family XhlA PF10779.9 CDJ82035.1 - 0.09 13.0 0.3 0.19 12.0 0.3 1.5 1 0 0 1 1 1 0 Haemolysin XhlA ELM2 PF01448.24 CDJ82038.1 - 2.3e-05 25.0 0.1 7.9e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-binding PF00249.31 CDJ82038.1 - 0.026 14.7 0.0 0.068 13.4 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CDJ82038.1 - 0.1 12.5 0.3 0.19 11.7 0.3 1.4 1 0 0 1 1 1 0 Myb DNA-binding like Pkinase PF00069.25 CDJ82039.1 - 2.7e-58 197.4 0.0 3.2e-58 197.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ82039.1 - 5.1e-33 114.5 0.0 6e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ82039.1 - 0.00035 20.0 0.3 0.00082 18.8 0.3 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CDJ82039.1 - 0.00041 20.1 0.1 0.012 15.3 0.0 2.1 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CDJ82039.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CDJ82039.1 - 0.01 14.8 0.2 0.14 11.1 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain RIO1 PF01163.22 CDJ82039.1 - 0.03 13.9 0.0 0.081 12.5 0.0 1.7 1 1 1 2 2 2 0 RIO1 family APH PF01636.23 CDJ82039.1 - 0.037 13.9 0.0 0.11 12.4 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Amidase PF01425.21 CDJ82040.1 - 5.5e-121 404.7 0.0 6.9e-121 404.3 0.0 1.1 1 0 0 1 1 1 1 Amidase Amidase PF01425.21 CDJ82041.1 - 1e-114 384.0 0.0 1.2e-114 383.8 0.0 1.1 1 0 0 1 1 1 1 Amidase Pkinase PF00069.25 CDJ82042.1 - 4.7e-66 222.9 0.0 5.6e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ82042.1 - 2.1e-30 105.9 0.0 3.4e-30 105.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ82042.1 - 0.00071 19.0 0.1 0.0013 18.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ82042.1 - 0.0013 18.7 1.0 0.011 15.7 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 CDJ82042.1 - 0.01 15.5 0.1 0.016 14.8 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 CDJ82042.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 CDJ82042.1 - 0.013 14.4 0.1 0.019 13.9 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 CDJ82043.1 - 3.8e-65 219.9 0.0 4.6e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ82043.1 - 1.3e-31 109.9 0.0 1.8e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ82043.1 - 3.8e-06 26.4 0.1 0.0002 20.8 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 CDJ82043.1 - 1.5e-05 24.5 0.1 2.3e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ82043.1 - 6.1e-05 23.1 0.0 0.0073 16.3 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 CDJ82043.1 - 0.00035 20.2 0.0 0.00056 19.6 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 CDJ82043.1 - 0.00077 18.5 0.1 0.0011 18.0 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 CDJ82043.1 - 0.078 12.6 0.1 0.17 11.5 0.1 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 CDJ82044.1 - 1.4e-58 198.3 0.0 1.7e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ82044.1 - 3.2e-27 95.5 0.0 4.5e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ82044.1 - 0.00025 21.0 0.1 0.02 14.8 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CDJ82044.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF3899 PF13038.6 CDJ82045.1 - 0.15 12.6 0.0 0.15 12.6 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) DUF1129 PF06570.11 CDJ82045.1 - 0.19 11.2 0.3 0.34 10.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) 7tm_7 PF08395.12 CDJ82045.1 - 7.6 5.6 6.7 4.4 6.4 3.2 2.0 1 1 1 2 2 2 0 7tm Chemosensory receptor UCR_TM PF02921.14 CDJ82046.1 - 2.2e-20 72.9 0.2 5.7e-20 71.6 0.2 1.7 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 CDJ82046.1 - 5.5e-12 45.5 0.2 1.6e-11 44.0 0.1 1.8 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Ntox25 PF15530.6 CDJ82046.1 - 0.08 13.1 0.0 0.15 12.2 0.0 1.4 1 1 0 1 1 1 0 Bacterial toxin 25 UCR_TM PF02921.14 CDJ82047.1 - 6.2e-16 58.6 0.1 1.4e-15 57.5 0.1 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 CDJ82047.1 - 3.6e-12 46.1 0.1 1.1e-11 44.5 0.1 1.8 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain MARVEL PF01284.23 CDJ82048.1 - 2.2e-19 69.9 12.0 2.9e-19 69.5 12.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain O-antigen_lig PF13425.6 CDJ82048.1 - 0.0061 15.4 0.0 0.011 14.6 0.0 1.4 1 1 0 1 1 1 1 O-antigen ligase like membrane protein NPCC PF08058.11 CDJ82048.1 - 0.017 15.2 0.1 0.033 14.2 0.1 1.5 1 0 0 1 1 1 0 Nuclear pore complex component ThiF PF00899.21 CDJ82049.1 - 9e-49 166.0 0.0 4.6e-48 163.7 0.0 1.8 1 1 0 1 1 1 1 ThiF family Rhodanese PF00581.20 CDJ82049.1 - 0.00018 22.0 0.0 0.0004 20.9 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain UDPG_MGDP_dh_N PF03721.14 CDJ82049.1 - 0.00026 20.6 0.1 0.00038 20.1 0.1 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 CDJ82049.1 - 0.00098 19.2 0.1 0.0025 17.9 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 CDJ82049.1 - 0.0035 17.6 0.0 0.007 16.6 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 CDJ82049.1 - 0.015 14.6 0.2 0.021 14.1 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 CDJ82049.1 - 0.016 14.9 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 CDJ82049.1 - 0.038 14.6 0.2 0.1 13.2 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CDJ82049.1 - 0.048 12.9 0.1 0.075 12.3 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CDJ82049.1 - 0.064 12.8 0.9 0.1 12.1 0.9 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 CDJ82049.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PglD_N PF17836.1 CDJ82049.1 - 0.14 12.8 0.3 0.38 11.4 0.2 1.8 2 0 0 2 2 2 0 PglD N-terminal domain 3HCDH_N PF02737.18 CDJ82049.1 - 0.23 11.3 0.0 0.35 10.7 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ESSS PF10183.9 CDJ82050.1 - 1e-11 45.0 0.5 1.8e-11 44.2 0.5 1.6 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Rhodanese PF00581.20 CDJ82051.1 - 4.9e-05 23.8 0.0 8.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain ABC_membrane_2 PF06472.15 CDJ82052.1 - 4.8e-94 314.7 4.6 6.7e-94 314.3 4.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 Pkinase PF00069.25 CDJ82054.1 - 4.1e-10 39.5 0.0 4.1e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ82054.1 - 4.7e-09 35.9 0.0 4.7e-09 35.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase PAT1 PF09770.9 CDJ82054.1 - 3 6.0 34.2 4.5 5.4 34.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF148 PF02520.17 CDJ82055.1 - 2.6e-18 66.1 4.0 3e-18 65.9 4.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 RTX_C PF08339.10 CDJ82055.1 - 0.0056 16.8 1.1 0.011 15.9 0.9 1.4 1 1 0 1 1 1 1 RTX C-terminal domain AEP1 PF17049.5 CDJ82055.1 - 0.045 12.8 0.5 0.055 12.6 0.5 1.1 1 0 0 1 1 1 0 ATPase expression protein 1 5_nucleotid PF05761.14 CDJ82055.1 - 0.066 12.1 0.5 0.086 11.7 0.5 1.0 1 0 0 1 1 1 0 5' nucleotidase family PAP_central PF04928.17 CDJ82055.1 - 0.067 12.2 0.0 0.11 11.5 0.0 1.3 1 1 0 1 1 1 0 Poly(A) polymerase central domain Baculo_PEP_C PF04513.12 CDJ82055.1 - 0.074 13.1 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Acetyltransf_11 PF13720.6 CDJ82055.1 - 0.093 13.2 0.2 1.5 9.4 0.0 2.1 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Allexi_40kDa PF05549.11 CDJ82055.1 - 0.18 11.3 0.1 0.23 10.9 0.1 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF148 PF02520.17 CDJ82056.1 - 1.9e-18 66.6 7.0 2.2e-18 66.3 7.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 APG6 PF04111.12 CDJ82056.1 - 0.0074 16.3 0.1 0.0097 15.9 0.1 1.3 1 1 0 1 1 1 1 Apg6 BARA domain AEP1 PF17049.5 CDJ82056.1 - 0.015 14.4 0.8 0.018 14.2 0.8 1.1 1 0 0 1 1 1 0 ATPase expression protein 1 Phage_30_3 PF08010.11 CDJ82056.1 - 0.016 15.0 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 RIX1 PF08167.12 CDJ82056.1 - 0.028 14.2 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis Baculo_PEP_C PF04513.12 CDJ82056.1 - 0.047 13.7 0.1 0.065 13.3 0.1 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Allexi_40kDa PF05549.11 CDJ82056.1 - 0.049 13.1 0.1 0.062 12.8 0.1 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF148 PF02520.17 CDJ82057.1 - 7.9e-25 87.1 5.6 9.4e-25 86.8 5.6 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 Acetyltransf_11 PF13720.6 CDJ82057.1 - 0.0023 18.3 0.1 0.18 12.3 0.0 2.2 2 0 0 2 2 2 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 SHE3 PF17078.5 CDJ82057.1 - 0.026 14.2 1.0 0.035 13.8 1.0 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Baculo_PEP_C PF04513.12 CDJ82057.1 - 0.071 13.2 1.2 0.092 12.8 1.2 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mustang PF15682.5 CDJ82057.1 - 0.097 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Musculoskeletal, temporally activated-embryonic nuclear protein 1 DUF148 PF02520.17 CDJ82058.1 - 1.6e-33 115.1 14.8 1.5e-21 76.5 6.4 2.1 2 0 0 2 2 2 2 Domain of unknown function DUF148 Baculo_PEP_C PF04513.12 CDJ82058.1 - 3.4e-05 23.9 1.1 0.09 12.8 0.2 2.1 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus HDV_ag PF01517.18 CDJ82058.1 - 9.4e-05 22.3 0.2 0.88 9.3 0.0 3.4 2 2 2 4 4 4 2 Hepatitis delta virus delta antigen RTX_C PF08339.10 CDJ82058.1 - 0.0002 21.4 4.5 0.038 14.1 1.0 2.3 2 0 0 2 2 2 2 RTX C-terminal domain PAP_central PF04928.17 CDJ82058.1 - 0.00047 19.2 0.1 0.11 11.4 0.0 2.2 2 0 0 2 2 2 1 Poly(A) polymerase central domain APG17 PF04108.12 CDJ82058.1 - 0.0007 18.8 2.1 0.1 11.7 0.7 2.1 2 0 0 2 2 2 1 Autophagy protein Apg17 P4Ha_N PF08336.11 CDJ82058.1 - 0.0024 17.9 1.9 0.97 9.4 0.3 2.5 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Viral_env_E26 PF11050.8 CDJ82058.1 - 0.003 17.0 0.3 1.9 7.8 0.0 2.1 2 0 0 2 2 2 2 Virus envelope protein E26 DUF4284 PF14112.6 CDJ82058.1 - 0.0059 17.5 2.7 1.3 10.0 0.4 2.2 2 0 0 2 2 2 1 Immunity protein 22 TolA_bind_tri PF16331.5 CDJ82058.1 - 0.0064 16.6 2.6 2.2 8.4 0.5 2.6 2 0 0 2 2 2 1 TolA binding protein trimerisation PHTB1_C PF14728.6 CDJ82058.1 - 0.0098 15.0 1.7 0.92 8.5 0.7 2.1 2 0 0 2 2 2 1 PTHB1 C-terminus DNA_repr_REX1B PF14966.6 CDJ82058.1 - 0.011 16.4 5.5 0.85 10.3 0.8 2.5 2 0 0 2 2 2 0 DNA repair REX1-B Allexi_40kDa PF05549.11 CDJ82058.1 - 0.014 15.0 1.1 0.45 10.0 0.3 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein LXG PF04740.12 CDJ82058.1 - 0.017 14.9 5.7 0.26 11.0 1.1 2.2 2 0 0 2 2 2 0 LXG domain of WXG superfamily DUF4404 PF14357.6 CDJ82058.1 - 0.017 15.8 1.1 2.9 8.6 0.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) Iron_permease PF04120.12 CDJ82058.1 - 0.022 14.5 1.6 5.3 6.8 0.1 2.3 2 0 0 2 2 2 0 Low affinity iron permease Med11 PF10280.9 CDJ82058.1 - 0.024 15.1 1.5 1.6 9.2 0.1 2.5 2 1 0 2 2 2 0 Mediator complex protein EspB_PE PF18625.1 CDJ82058.1 - 0.025 15.0 0.7 10 6.7 0.1 2.5 2 0 0 2 2 2 0 ESX-1 secreted protein B PE domain PLA2G12 PF06951.11 CDJ82058.1 - 0.025 14.5 0.1 1.7 8.5 0.0 2.3 2 1 0 2 2 2 0 Group XII secretory phospholipase A2 precursor (PLA2G12) DUF3683 PF12447.8 CDJ82058.1 - 0.025 14.7 4.0 0.67 10.1 0.2 3.2 4 0 0 4 4 3 0 Protein of unknown function (DUF3683) Acetyltransf_11 PF13720.6 CDJ82058.1 - 0.026 15.0 0.4 0.98 9.9 0.0 2.9 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 FliT PF05400.13 CDJ82058.1 - 0.041 14.7 0.8 11 6.9 0.0 2.5 2 1 0 2 2 2 0 Flagellar protein FliT FANCI_S2 PF14676.6 CDJ82058.1 - 0.05 13.9 0.2 4.7 7.5 0.1 2.3 2 0 0 2 2 2 0 FANCI solenoid 2 Syntaxin_2 PF14523.6 CDJ82058.1 - 0.054 13.9 3.3 4.8 7.6 0.9 2.3 2 0 0 2 2 2 0 Syntaxin-like protein DUF3071 PF11268.8 CDJ82058.1 - 0.072 13.2 0.5 1.8 8.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3071) RIX1 PF08167.12 CDJ82058.1 - 0.084 12.6 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis ORF_12_N PF18042.1 CDJ82058.1 - 0.094 13.1 0.2 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 ORF 12 gene product N-terminal Mobilization_B PF17511.2 CDJ82058.1 - 0.1 12.9 2.1 3.3 8.1 0.3 2.2 2 0 0 2 2 2 0 Mobilization protein B BLOC1_2 PF10046.9 CDJ82058.1 - 0.11 12.8 8.2 3 8.2 0.2 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 INCENP_ARK-bind PF03941.15 CDJ82058.1 - 0.12 12.3 0.0 4.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region YkyA PF10368.9 CDJ82058.1 - 0.14 11.8 13.5 2.3 7.9 0.4 2.4 2 1 0 2 2 2 0 Putative cell-wall binding lipoprotein HAGH_C PF16123.5 CDJ82058.1 - 0.14 12.7 1.9 15 6.2 0.1 3.0 3 0 0 3 3 2 0 Hydroxyacylglutathione hydrolase C-terminus Cor1 PF04803.12 CDJ82058.1 - 0.15 12.2 8.7 1.4 9.1 2.3 2.5 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region EloA-BP1 PF15870.5 CDJ82058.1 - 0.16 12.2 5.1 0.42 10.9 2.1 2.6 2 1 0 2 2 2 0 ElonginA binding-protein 1 PRKG1_interact PF15898.5 CDJ82058.1 - 0.17 12.8 3.7 2.7 9.0 0.8 2.4 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain KIP1 PF07765.12 CDJ82058.1 - 0.17 12.0 1.4 4.1 7.6 0.3 2.4 2 0 0 2 2 2 0 KIP1-like protein SseC PF04888.12 CDJ82058.1 - 0.19 11.3 12.3 0.81 9.2 3.6 2.6 2 1 0 2 2 2 0 Secretion system effector C (SseC) like family CREPT PF16566.5 CDJ82058.1 - 0.21 11.8 2.4 5.5 7.1 0.5 2.4 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour BBS1 PF14779.6 CDJ82058.1 - 0.22 10.9 7.5 0.16 11.3 2.2 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 DUF1664 PF07889.12 CDJ82058.1 - 0.33 11.0 6.6 2.6 8.1 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3015 PF11220.8 CDJ82058.1 - 0.35 10.7 5.5 4.5 7.1 1.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3015) DUF4298 PF14131.6 CDJ82058.1 - 0.44 10.5 2.8 7.4 6.6 0.0 3.2 4 0 0 4 4 3 0 Domain of unknown function (DUF4298) Fib_alpha PF08702.10 CDJ82058.1 - 0.79 9.9 7.9 4.5 7.5 3.2 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.12 CDJ82058.1 - 0.79 9.7 9.0 3.8 7.5 2.9 2.2 2 0 0 2 2 2 0 Laminin Domain II SHE3 PF17078.5 CDJ82058.1 - 0.84 9.3 7.5 5.4 6.7 0.3 2.2 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 YMF19 PF02326.15 CDJ82058.1 - 1 10.2 3.1 15 6.4 0.1 3.0 2 1 1 3 3 3 0 Plant ATP synthase F0 Mt_ATP-synt_D PF05873.12 CDJ82058.1 - 1.1 9.1 13.4 2.9 7.7 0.8 2.6 2 1 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) LUC7 PF03194.15 CDJ82058.1 - 1.9 8.1 6.5 9 5.9 2.0 2.2 2 0 0 2 2 2 0 LUC7 N_terminus HIP1_clath_bdg PF16515.5 CDJ82058.1 - 2.5 8.8 9.6 9.8 6.9 4.0 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Mer2 PF09074.10 CDJ82058.1 - 3.5 7.4 10.0 7.4 6.3 3.2 2.1 2 0 0 2 2 2 0 Mer2 PRESAN PF09687.10 CDJ82058.1 - 4 8.0 8.9 8.3 7.0 0.9 2.9 2 1 1 3 3 3 0 Plasmodium RESA N-terminal DUF2059 PF09832.9 CDJ82058.1 - 4.2 7.5 8.0 14 5.8 1.2 2.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2059) ISG65-75 PF11727.8 CDJ82058.1 - 4.6 6.4 8.4 13 4.9 2.8 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein DUF948 PF06103.11 CDJ82058.1 - 5.7 7.3 11.7 34 4.8 1.1 3.3 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) T3SS_basalb_I PF17001.5 CDJ82058.1 - 9.6 6.9 12.3 17 6.1 0.7 3.8 2 2 2 4 4 4 0 Type III secretion basal body protein I, YscI, HrpB, PscI DUF148 PF02520.17 CDJ82059.1 - 8.6e-44 148.1 16.1 5e-24 84.5 3.2 2.1 2 0 0 2 2 2 2 Domain of unknown function DUF148 Acetyltransf_11 PF13720.6 CDJ82059.1 - 0.00019 21.8 2.8 0.83 10.2 0.0 3.9 4 0 0 4 4 4 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Baculo_PEP_C PF04513.12 CDJ82059.1 - 0.0002 21.4 1.7 0.11 12.5 0.1 2.2 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus TolA_bind_tri PF16331.5 CDJ82059.1 - 0.0015 18.6 2.8 0.41 10.8 0.3 2.7 2 0 0 2 2 2 1 TolA binding protein trimerisation P4Ha_N PF08336.11 CDJ82059.1 - 0.0021 18.1 1.0 1.1 9.3 0.1 2.5 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Lsr2 PF11774.8 CDJ82059.1 - 0.0039 17.3 0.1 2.4 8.4 0.0 2.6 2 0 0 2 2 2 1 Lsr2 Retrotran_gag_2 PF14223.6 CDJ82059.1 - 0.0065 16.1 1.4 2.8 7.6 0.2 2.3 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type INCENP_ARK-bind PF03941.15 CDJ82059.1 - 0.0072 16.2 0.1 3.5 7.7 0.0 2.5 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Med21 PF11221.8 CDJ82059.1 - 0.0086 16.3 2.1 0.45 10.8 1.6 2.5 2 1 0 2 2 2 1 Subunit 21 of Mediator complex RTX_C PF08339.10 CDJ82059.1 - 0.0098 16.0 3.6 0.1 12.7 0.4 2.3 2 0 0 2 2 2 1 RTX C-terminal domain SAM_3 PF18016.1 CDJ82059.1 - 0.01 15.6 1.4 0.92 9.4 0.1 2.5 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Spore_Cse60 PF10957.8 CDJ82059.1 - 0.016 15.2 0.2 6.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Sporulation protein Cse60 HTH_WhiA PF02650.14 CDJ82059.1 - 0.03 14.7 5.5 0.049 14.0 0.2 2.6 3 0 0 3 3 2 0 WhiA C-terminal HTH domain Peripla_BP_2 PF01497.18 CDJ82059.1 - 0.062 12.9 3.0 0.21 11.1 0.3 2.3 2 1 0 2 2 2 0 Periplasmic binding protein SHE3 PF17078.5 CDJ82059.1 - 0.071 12.8 8.5 0.57 9.9 0.7 2.2 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 HisK_N PF09385.10 CDJ82059.1 - 0.08 12.9 3.0 0.45 10.5 0.1 2.3 2 0 0 2 2 2 0 Histidine kinase N terminal HTH_ABP1_N PF18107.1 CDJ82059.1 - 0.11 12.3 0.0 22 4.9 0.0 2.6 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain DIL PF01843.19 CDJ82059.1 - 0.12 12.6 1.2 8.5 6.7 0.1 2.4 2 0 0 2 2 2 0 DIL domain FliT PF05400.13 CDJ82059.1 - 0.21 12.4 4.8 8.8 7.2 0.3 3.0 3 1 0 3 3 2 0 Flagellar protein FliT PRKG1_interact PF15898.5 CDJ82059.1 - 0.26 12.2 5.2 3.8 8.5 0.6 2.5 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Not3 PF04065.15 CDJ82059.1 - 0.29 10.5 6.9 0.33 10.4 1.8 2.3 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Allexi_40kDa PF05549.11 CDJ82059.1 - 0.33 10.4 3.9 3.5 7.1 0.4 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein DNA_repr_REX1B PF14966.6 CDJ82059.1 - 0.33 11.6 5.0 1.5 9.6 0.7 2.8 2 1 1 3 3 2 0 DNA repair REX1-B DUF948 PF06103.11 CDJ82059.1 - 0.42 10.9 7.7 5.4 7.3 0.2 3.3 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) COG2 PF06148.11 CDJ82059.1 - 0.57 10.3 5.9 8.7 6.4 0.2 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Laminin_II PF06009.12 CDJ82059.1 - 0.68 10.0 8.4 5.3 7.1 0.6 2.3 2 0 0 2 2 2 0 Laminin Domain II YkyA PF10368.9 CDJ82059.1 - 0.98 9.1 16.5 0.76 9.4 4.6 3.0 2 1 1 3 3 3 0 Putative cell-wall binding lipoprotein LXG PF04740.12 CDJ82059.1 - 1.4 8.6 9.0 5 6.8 1.2 2.2 2 0 0 2 2 2 0 LXG domain of WXG superfamily Mt_ATP-synt_D PF05873.12 CDJ82059.1 - 1.5 8.7 11.2 10 5.9 4.2 3.0 2 2 2 4 4 4 0 ATP synthase D chain, mitochondrial (ATP5H) Mer2 PF09074.10 CDJ82059.1 - 1.5 8.6 9.4 3.7 7.3 2.1 2.2 2 0 0 2 2 2 0 Mer2 Fib_alpha PF08702.10 CDJ82059.1 - 1.9 8.6 8.2 6.6 6.9 2.3 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF2570 PF10828.8 CDJ82059.1 - 2.2 8.1 6.0 7.8 6.4 0.2 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF2570) FlaC_arch PF05377.11 CDJ82059.1 - 6.6 7.2 9.1 37 4.8 0.1 4.0 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF148 PF02520.17 CDJ82060.1 - 4.8e-21 74.9 9.4 5.8e-21 74.6 9.4 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 Acetyltransf_11 PF13720.6 CDJ82060.1 - 0.0044 17.5 1.2 0.12 12.8 0.2 2.2 1 1 1 2 2 2 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Fib_alpha PF08702.10 CDJ82060.1 - 0.037 14.2 6.3 0.058 13.6 6.3 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family HisK_N PF09385.10 CDJ82060.1 - 0.042 13.8 2.9 0.076 13.0 2.8 1.6 1 1 0 1 1 1 0 Histidine kinase N terminal PhoU_div PF01865.16 CDJ82060.1 - 0.05 12.9 2.0 0.064 12.6 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF47 Flexi_CP_N PF08358.10 CDJ82060.1 - 0.14 12.2 1.2 0.33 11.0 0.3 2.1 2 0 0 2 2 2 0 Carlavirus coat PIEZO PF15917.5 CDJ82060.1 - 0.19 11.2 4.6 0.42 10.1 2.4 1.9 1 1 1 2 2 2 0 Piezo DUF148 PF02520.17 CDJ82061.1 - 5.1e-22 78.0 1.9 6.1e-22 77.8 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 UPF0058 PF01893.16 CDJ82061.1 - 0.00024 21.3 0.0 0.00046 20.4 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised protein family UPF0058 SAM_3 PF18016.1 CDJ82061.1 - 0.045 13.6 0.1 0.086 12.7 0.1 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) EppA_BapA PF07268.11 CDJ82061.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 1 0 1 1 1 0 Exported protein precursor (EppA/BapA) IGR PF09597.10 CDJ82061.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 IGR protein motif Lectin_C PF00059.21 CDJ82062.1 - 8.1e-24 84.4 0.7 1e-23 84.1 0.7 1.1 1 0 0 1 1 1 1 Lectin C-type domain DUF148 PF02520.17 CDJ82063.1 - 1.3e-24 86.4 7.2 1.1e-23 83.5 5.7 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF148 DUF4404 PF14357.6 CDJ82063.1 - 0.0037 17.9 0.4 0.023 15.3 1.1 2.0 2 1 1 3 3 3 1 Domain of unknown function (DUF4404) Baculo_PEP_C PF04513.12 CDJ82063.1 - 0.0044 17.1 0.4 0.0095 16.0 0.1 1.7 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus MAP65_ASE1 PF03999.12 CDJ82063.1 - 0.0054 15.5 1.8 0.0064 15.2 1.8 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Adenylate_cycl PF01295.18 CDJ82063.1 - 0.02 13.6 2.1 0.026 13.2 2.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase, class-I NB-ARC PF00931.22 CDJ82063.1 - 0.022 14.0 1.5 0.027 13.6 1.5 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF948 PF06103.11 CDJ82063.1 - 0.022 15.0 1.4 0.13 12.5 1.2 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) YkyA PF10368.9 CDJ82063.1 - 0.023 14.3 6.1 0.053 13.2 2.4 2.0 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein DUF1043 PF06295.12 CDJ82063.1 - 0.028 14.4 4.3 0.041 13.9 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) RmuC PF02646.16 CDJ82063.1 - 0.028 13.6 2.9 0.04 13.1 2.9 1.3 1 0 0 1 1 1 0 RmuC family DHC PF09626.10 CDJ82063.1 - 0.033 15.1 3.3 0.054 14.4 3.3 1.4 1 0 0 1 1 1 0 Dihaem cytochrome c Allexi_40kDa PF05549.11 CDJ82063.1 - 0.036 13.6 1.9 0.052 13.1 1.9 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Fzo_mitofusin PF04799.13 CDJ82063.1 - 0.049 13.2 3.2 0.073 12.6 3.2 1.3 1 0 0 1 1 1 0 fzo-like conserved region Jnk-SapK_ap_N PF09744.9 CDJ82063.1 - 0.052 13.8 3.4 0.07 13.4 3.4 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF1672 PF07901.11 CDJ82063.1 - 0.072 12.4 2.8 0.097 12.0 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) SpmSyn_N PF17950.1 CDJ82063.1 - 0.12 12.6 1.5 0.21 11.8 0.4 2.0 1 1 1 2 2 2 0 S-adenosylmethionine decarboxylase N -terminal Adeno_E3_15_3 PF03307.14 CDJ82063.1 - 0.15 12.0 0.8 0.26 11.2 0.5 1.5 1 1 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region Acetyltransf_9 PF13527.7 CDJ82063.1 - 0.16 12.1 1.1 0.81 9.8 0.2 2.1 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain PMC2NT PF08066.12 CDJ82063.1 - 0.18 12.5 0.3 0.43 11.3 0.2 1.7 1 1 0 1 1 1 0 PMC2NT (NUC016) domain Acetyltransf_11 PF13720.6 CDJ82063.1 - 0.23 11.9 1.8 3.8 8.0 0.4 2.2 1 1 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 7TM_GPCR_Str PF10326.9 CDJ82067.1 - 8.9e-06 25.3 9.9 1.1e-05 25.0 9.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srj PF10319.9 CDJ82067.1 - 0.0019 17.6 5.9 0.0026 17.2 5.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj rve PF00665.26 CDJ82068.1 - 8.6e-21 74.3 0.0 6.4e-20 71.5 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 CDJ82068.1 - 2.1e-05 24.2 0.0 6e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DUF2293 PF10056.9 CDJ82068.1 - 0.04 14.2 0.2 0.14 12.5 0.2 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2293) PBP PF01161.20 CDJ82069.1 - 1.7e-21 77.0 0.0 2e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Acetyltransf_7 PF13508.7 CDJ82071.1 - 0.00031 21.1 0.0 0.00054 20.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDJ82071.1 - 0.0027 17.6 0.0 0.0052 16.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDJ82071.1 - 0.04 14.2 0.0 0.059 13.6 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family NOD2_WH PF17779.1 CDJ82071.1 - 0.13 12.7 0.0 0.44 10.9 0.0 1.9 2 0 0 2 2 2 0 NOD2 winged helix domain Glyoxalase_4 PF13669.6 CDJ82072.1 - 6.7e-08 32.8 0.0 7.7e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 CDJ82072.1 - 0.014 15.6 0.0 0.015 15.5 0.0 1.1 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF1894 PF08979.11 CDJ82072.1 - 0.11 12.9 0.1 0.14 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1894) Glyoxalase_3 PF13468.6 CDJ82072.1 - 0.17 12.0 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Glyoxalase-like domain RdRP_4 PF02123.16 CDJ82073.1 - 0.0029 16.6 0.0 0.0048 15.8 0.0 1.2 1 0 0 1 1 1 1 Viral RNA-directed RNA-polymerase RRM_1 PF00076.22 CDJ82074.1 - 3.4e-25 87.7 0.1 4e-25 87.4 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ82074.1 - 0.0016 18.0 0.0 0.0018 17.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_1 PF00515.28 CDJ82075.1 - 2.8e-40 134.5 3.5 7.3e-10 38.2 0.0 6.3 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ82075.1 - 5.4e-32 107.3 4.5 1.4e-08 34.2 0.0 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ82075.1 - 1.9e-28 97.9 5.1 2e-10 40.2 0.0 6.9 3 1 4 7 7 7 5 TPR repeat TPR_8 PF13181.6 CDJ82075.1 - 8e-28 94.3 0.4 9.8e-06 25.4 0.0 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ82075.1 - 2.2e-27 93.4 7.6 2.9e-05 24.1 0.6 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ82075.1 - 1.6e-22 79.5 5.4 8.4e-08 32.4 0.0 5.1 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ82075.1 - 1.2e-18 67.4 0.1 9.4e-07 29.4 0.0 4.2 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ82075.1 - 4.4e-16 57.6 4.1 0.0081 16.1 0.0 6.7 7 2 0 7 7 7 4 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ82075.1 - 5.8e-14 51.4 12.5 0.00025 20.8 0.8 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ82075.1 - 5.9e-12 45.9 3.2 0.0018 18.8 0.0 4.5 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ82075.1 - 9.9e-12 44.6 1.4 0.0012 19.4 0.0 5.9 3 1 5 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ82075.1 - 4.1e-06 27.1 0.1 0.49 11.1 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ82075.1 - 7.1e-05 22.9 0.1 0.015 15.4 0.0 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 CDJ82075.1 - 0.00011 22.5 0.0 1.6 9.6 0.0 4.9 6 1 0 6 6 4 1 Tetratricopeptide repeat NARP1 PF12569.8 CDJ82075.1 - 0.0003 19.8 0.1 0.029 13.3 0.0 2.4 2 1 0 3 3 3 1 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 CDJ82075.1 - 0.0004 20.6 0.3 0.045 14.0 0.0 3.4 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 CDJ82075.1 - 0.0012 18.1 0.1 0.35 10.0 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC5 PF12862.7 CDJ82075.1 - 0.004 17.2 0.0 0.046 13.8 0.0 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 5 FAT PF02259.23 CDJ82075.1 - 0.022 14.0 0.2 0.83 8.8 0.0 2.4 2 1 1 3 3 3 0 FAT domain EpsG PF14897.6 CDJ82075.1 - 0.037 13.3 2.0 0.053 12.8 2.0 1.1 1 0 0 1 1 1 0 EpsG family Type_III_YscG PF09477.10 CDJ82075.1 - 0.039 14.0 0.7 0.56 10.3 0.2 2.6 2 1 0 2 2 1 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_20 PF14561.6 CDJ82075.1 - 0.068 13.5 0.2 14 6.1 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 CDJ82075.1 - 0.15 12.5 0.6 12 6.3 0.1 2.9 2 1 2 4 4 4 0 Bacterial transcriptional activator domain DUF1736 PF08409.11 CDJ82075.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1736) Laminin_G_2 PF02210.24 CDJ82076.1 - 1.3e-59 200.3 0.0 2.8e-16 60.2 0.0 4.9 5 0 0 5 5 5 4 Laminin G domain Laminin_G_1 PF00054.23 CDJ82076.1 - 2.6e-55 186.2 0.0 6.4e-17 62.0 0.0 4.5 4 0 0 4 4 4 4 Laminin G domain Laminin_G_3 PF13385.6 CDJ82076.1 - 5.1e-05 23.5 0.0 8.1 6.6 0.0 3.8 3 0 0 3 3 3 3 Concanavalin A-like lectin/glucanases superfamily End3 PF12761.7 CDJ82076.1 - 0.38 10.9 2.8 0.76 9.9 2.8 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 INSC_LBD PF16748.5 CDJ82077.1 - 0.025 14.0 0.1 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Inscuteable LGN-binding domain Glyoxalase PF00903.25 CDJ82078.1 - 1.2e-06 28.7 0.0 4.1e-05 23.8 0.0 2.6 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NAD_binding_2 PF03446.15 CDJ82079.1 - 1.6e-42 145.4 1.2 2.2e-42 144.9 1.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CDJ82079.1 - 3e-32 111.4 0.0 5.1e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 CDJ82079.1 - 4.2e-06 27.2 0.1 3.5e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 CDJ82079.1 - 7.8e-06 25.4 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 CDJ82079.1 - 0.00019 21.4 0.2 0.0047 16.8 0.2 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 CDJ82079.1 - 0.014 15.7 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 CDJ82079.1 - 0.046 13.4 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 CDJ82079.1 - 0.077 12.6 0.3 0.17 11.4 0.1 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CHCH PF06747.13 CDJ82080.1 - 7.1e-08 32.4 6.4 1.1e-07 31.8 6.4 1.3 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.9 CDJ82080.1 - 3.6e-06 27.2 9.0 4.7e-06 26.8 9.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Cmc1 PF08583.10 CDJ82080.1 - 0.011 15.8 1.2 0.015 15.3 1.2 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Fringe PF02434.16 CDJ82081.1 - 6.5e-05 22.5 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Fringe-like Avl9 PF09794.9 CDJ82081.1 - 0.058 12.1 0.0 0.064 11.9 0.0 1.2 1 0 0 1 1 1 0 Transport protein Avl9 EGF PF00008.27 CDJ82082.1 - 0.013 15.7 3.5 0.023 15.0 3.5 1.3 1 0 0 1 1 1 0 EGF-like domain gag-asp_proteas PF13975.6 CDJ82084.1 - 5.5e-05 23.6 0.3 0.00012 22.6 0.3 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 CDJ82085.1 - 1.3e-31 109.9 0.1 1.9e-31 109.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDJ82085.1 - 8.6e-31 106.3 0.0 1.8e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ82085.1 - 2.8e-30 104.3 0.0 5.8e-30 103.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SAICAR_synt PF01259.18 CDJ82087.1 - 2.1e-53 181.5 0.1 3e-53 181.0 0.1 1.2 1 0 0 1 1 1 1 SAICAR synthetase AIRC PF00731.20 CDJ82087.1 - 1.8e-35 121.7 0.1 2.9e-35 121.0 0.1 1.3 1 0 0 1 1 1 1 AIR carboxylase Activin_recp PF01064.23 CDJ82089.1 - 2.9e-05 25.0 11.5 3.8e-05 24.7 11.5 1.1 1 0 0 1 1 1 1 Activin types I and II receptor domain Toxin_TOLIP PF00087.21 CDJ82089.1 - 3.8 7.8 17.1 20 5.5 16.9 2.0 1 1 0 1 1 1 0 Snake toxin and toxin-like protein BTB_2 PF02214.22 CDJ82090.1 - 7.9e-05 22.9 0.1 0.00012 22.3 0.1 1.4 1 1 0 1 1 1 1 BTB/POZ domain Yippee-Mis18 PF03226.14 CDJ82091.1 - 5.6e-14 52.2 1.4 7.4e-14 51.8 1.4 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly ATPgrasp_YheCD PF14398.6 CDJ82091.1 - 0.016 14.5 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 YheC/D like ATP-grasp Jas PF16135.5 CDJ82091.1 - 0.024 14.8 1.3 0.027 14.6 0.4 1.6 1 1 0 1 1 1 0 TPL-binding domain in jasmonate signalling Pkinase_Tyr PF07714.17 CDJ82093.1 - 1.6e-75 253.7 0.0 2.8e-75 252.9 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ82093.1 - 1.6e-44 152.3 0.0 2.6e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ82093.1 - 5.8e-05 22.5 0.0 0.00013 21.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CDJ82093.1 - 0.0031 16.9 0.6 0.01 15.2 0.6 1.9 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDJ82093.1 - 0.032 13.2 0.0 0.064 12.2 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain SH2 PF00017.24 CDJ82093.1 - 0.037 14.1 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 SH2 domain SIL1 PF16782.5 CDJ82093.1 - 0.15 11.2 2.9 0.25 10.5 2.9 1.2 1 0 0 1 1 1 0 Nucleotide exchange factor SIL1 Patched PF02460.18 CDJ82095.1 - 9.7e-210 698.7 8.4 1.1e-209 698.5 8.4 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 CDJ82095.1 - 9.3e-26 90.5 1.3 9.3e-26 90.5 1.3 2.8 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation SecD_SecF PF02355.16 CDJ82095.1 - 8e-05 22.1 6.0 8e-05 22.1 6.0 2.1 2 0 0 2 2 2 1 Protein export membrane protein MMPL PF03176.15 CDJ82095.1 - 0.066 12.1 11.4 0.015 14.2 0.8 2.3 2 0 0 2 2 2 0 MMPL family ACR_tran PF00873.19 CDJ82095.1 - 0.28 8.8 9.3 0.51 7.9 9.3 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family RT_RNaseH_2 PF17919.1 CDJ82096.1 - 1.9e-28 98.5 0.0 2.8e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ82096.1 - 2.6e-24 85.5 0.0 3.8e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ82097.1 - 2.2e-24 85.9 0.0 4.1e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ82097.1 - 2.7e-16 59.4 0.3 5.3e-16 58.5 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CDJ82097.1 - 4.6e-05 23.1 0.2 0.00013 21.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 CDJ82097.1 - 0.0017 18.5 0.1 0.0051 17.0 0.0 1.8 2 0 0 2 2 2 1 H2C2 zinc finger RVT_1 PF00078.27 CDJ82098.1 - 3.2e-16 59.5 0.0 7.3e-16 58.4 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CDJ82098.1 - 2.7e-08 34.2 0.0 5.8e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ82098.1 - 1.2e-07 32.2 0.0 2.7e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ82098.1 - 6.7e-05 23.1 0.0 0.00016 22.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Gemini_C4 PF01492.17 CDJ82098.1 - 0.083 12.8 0.3 0.25 11.3 0.1 1.9 2 0 0 2 2 2 0 Geminivirus C4 protein PNMA PF14893.6 CDJ82099.1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 PNMA Tn7_Tnp_TnsA_C PF08721.11 CDJ82099.1 - 0.027 15.1 0.2 24 5.6 0.0 3.3 4 0 0 4 4 4 0 TnsA endonuclease C terminal L31 PF09784.9 CDJ82099.1 - 0.41 11.1 3.0 0.49 10.8 0.0 2.4 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L31 YjfB_motility PF14070.6 CDJ82099.1 - 0.56 10.4 5.6 11 6.3 0.5 2.4 2 0 0 2 2 2 0 Putative motility protein Ribosomal_S27 PF01599.19 CDJ82101.1 - 2.6 8.3 6.9 0.15 12.3 1.5 1.7 2 0 0 2 2 2 0 Ribosomal protein S27a DUF3052 PF11253.8 CDJ82102.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3052) DZR PF12773.7 CDJ82103.1 - 0.064 13.3 1.7 0.14 12.2 1.7 1.6 1 0 0 1 1 1 0 Double zinc ribbon DUF4907 PF16250.5 CDJ82104.1 - 2.5 8.1 5.9 13 5.7 0.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4907) RUN PF02759.19 CDJ82106.1 - 4.5e-14 52.6 0.1 5.6e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 RUN domain DDE_3 PF13358.6 CDJ82107.1 - 4.5e-12 46.0 0.1 5e-12 45.8 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease RabGAP-TBC PF00566.18 CDJ82108.1 - 2.3e-45 154.9 0.0 4.4e-45 154.0 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_1 PF00018.28 CDJ82108.1 - 2.5e-10 39.8 0.0 4.8e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDJ82108.1 - 6.4e-10 38.6 0.1 1.4e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CDJ82108.1 - 4.8e-09 35.9 0.0 1.3e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Nucleotid_trans PF03407.16 CDJ82109.1 - 1.2e-31 110.3 0.9 1.5e-31 110.0 0.9 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Patched PF02460.18 CDJ82110.1 - 3.4e-74 250.4 18.3 1.1e-44 152.7 0.0 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 CDJ82110.1 - 2e-36 125.1 5.0 2e-36 125.1 5.0 3.1 4 0 0 4 4 4 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 CDJ82110.1 - 0.0014 17.6 3.6 0.0014 17.6 3.6 2.4 2 0 0 2 2 2 2 MMPL family Gemini_mov PF01708.16 CDJ82110.1 - 0.067 13.0 0.0 0.3 10.9 0.0 2.1 1 0 0 1 1 1 0 Geminivirus putative movement protein OGG_N PF07934.12 CDJ82111.1 - 6.9e-25 87.5 0.1 1.2e-24 86.7 0.1 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 CDJ82111.1 - 5.8e-08 33.2 0.0 1e-07 32.4 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF4481 PF14800.6 CDJ82112.1 - 1.2e-10 41.3 3.8 1.3e-07 31.4 1.4 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4481) CoA_binding_3 PF13727.6 CDJ82112.1 - 0.0014 18.7 2.0 0.0023 18.0 2.0 1.3 1 0 0 1 1 1 1 CoA-binding domain DUF4271 PF14093.6 CDJ82112.1 - 0.036 14.0 4.9 0.052 13.5 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) Metallophos PF00149.28 CDJ82113.1 - 2.2e-13 51.2 3.0 2.2e-13 51.2 3.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Filament PF00038.21 CDJ82115.1 - 1.6e-70 238.1 56.8 2.1e-68 231.2 56.8 2.1 1 1 0 1 1 1 1 Intermediate filament protein CENP-F_leu_zip PF10473.9 CDJ82115.1 - 7.1e-06 26.1 52.3 0.0024 17.9 21.0 3.9 2 2 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 CDJ82115.1 - 3.1e-05 24.5 64.9 0.48 10.9 6.5 5.8 1 1 4 5 5 5 2 Apg6 coiled-coil region ERM PF00769.19 CDJ82115.1 - 6.9e-05 22.8 28.5 6.9e-05 22.8 28.5 3.4 1 1 2 3 3 3 1 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.12 CDJ82115.1 - 7.5e-05 22.8 54.1 0.012 15.7 6.2 4.7 1 1 3 5 5 5 4 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 CDJ82115.1 - 0.00015 20.8 53.7 0.0007 18.6 13.7 3.6 1 1 3 4 4 4 3 Spc7 kinetochore protein Myosin_tail_1 PF01576.19 CDJ82115.1 - 0.00031 18.7 55.9 0.0052 14.7 10.9 2.6 1 1 1 2 2 2 2 Myosin tail GAS PF13851.6 CDJ82115.1 - 0.00043 19.7 53.7 0.014 14.7 10.7 4.1 2 1 0 3 3 3 2 Growth-arrest specific micro-tubule binding Lebercilin PF15619.6 CDJ82115.1 - 0.00075 19.2 52.3 0.02 14.5 21.1 3.2 1 1 1 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease Uso1_p115_C PF04871.13 CDJ82115.1 - 0.00085 19.7 17.7 0.00085 19.7 17.7 4.6 1 1 4 5 5 5 1 Uso1 / p115 like vesicle tethering protein, C terminal region ATG16 PF08614.11 CDJ82115.1 - 0.0011 19.2 54.9 0.2 11.9 8.5 4.0 1 1 2 3 3 3 3 Autophagy protein 16 (ATG16) YabA PF06156.13 CDJ82115.1 - 0.0016 19.0 42.1 0.026 15.2 4.9 6.0 1 1 5 6 6 6 1 Initiation control protein YabA DUF948 PF06103.11 CDJ82115.1 - 0.0044 17.3 15.6 0.0065 16.7 0.4 4.6 3 2 1 4 4 3 2 Bacterial protein of unknown function (DUF948) CENP-H PF05837.12 CDJ82115.1 - 0.0053 17.2 6.6 0.0053 17.2 6.6 5.3 2 2 3 5 5 5 1 Centromere protein H (CENP-H) SOGA PF11365.8 CDJ82115.1 - 0.0083 17.2 37.9 0.15 13.2 6.3 5.5 1 1 4 5 5 5 3 Protein SOGA bZIP_1 PF00170.21 CDJ82115.1 - 0.0089 16.1 1.0 0.0089 16.1 1.0 6.3 5 1 0 5 5 5 2 bZIP transcription factor Snapin_Pallidin PF14712.6 CDJ82115.1 - 0.018 15.5 6.0 0.018 15.5 6.0 5.8 3 2 4 7 7 5 0 Snapin/Pallidin PRKG1_interact PF15898.5 CDJ82115.1 - 0.025 15.5 12.2 0.025 15.5 12.2 5.6 1 1 4 6 6 6 0 cGMP-dependent protein kinase interacting domain FPP PF05911.11 CDJ82115.1 - 0.026 12.7 41.8 0.0092 14.2 15.9 2.3 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Prefoldin_2 PF01920.20 CDJ82115.1 - 0.039 13.9 39.9 0.39 10.7 2.0 6.1 3 3 3 6 6 6 0 Prefoldin subunit bZIP_2 PF07716.15 CDJ82115.1 - 0.041 14.0 0.4 0.041 14.0 0.4 7.9 5 2 3 8 8 8 0 Basic region leucine zipper HALZ PF02183.18 CDJ82115.1 - 0.041 14.1 1.2 0.041 14.1 1.2 6.8 7 0 0 7 7 6 0 Homeobox associated leucine zipper DUF3584 PF12128.8 CDJ82115.1 - 0.075 10.5 48.2 0.021 12.4 45.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) MAD PF05557.13 CDJ82115.1 - 0.091 11.1 55.5 0.21 9.9 35.5 2.6 1 1 1 2 2 2 0 Mitotic checkpoint protein ADIP PF11559.8 CDJ82115.1 - 0.17 11.9 51.0 0.053 13.6 4.0 5.6 1 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding UPF0242 PF06785.11 CDJ82115.1 - 0.19 11.8 53.4 2.8 8.0 11.6 3.5 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 CDJ82115.1 - 0.22 10.6 39.1 0.029 13.5 15.4 3.2 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlaC_arch PF05377.11 CDJ82115.1 - 0.22 11.9 27.0 0.19 12.1 1.3 5.9 5 1 0 6 6 5 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 CDJ82115.1 - 0.25 10.6 39.9 0.21 10.9 18.2 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 CDJ82115.1 - 0.32 11.4 53.6 1.7 9.1 11.4 3.7 1 1 1 3 3 3 0 Fez1 FlxA PF14282.6 CDJ82115.1 - 0.4 10.7 39.4 3.1 7.8 6.2 5.6 1 1 4 6 6 6 0 FlxA-like protein KASH_CCD PF14662.6 CDJ82115.1 - 0.41 10.5 56.1 2.4 7.9 20.3 3.5 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH DivIC PF04977.15 CDJ82115.1 - 0.61 9.9 44.1 0.18 11.6 3.6 6.6 4 3 2 6 6 5 0 Septum formation initiator DUF3450 PF11932.8 CDJ82115.1 - 0.63 9.3 46.9 0.22 10.8 16.9 4.1 1 1 2 4 4 4 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.8 CDJ82115.1 - 0.97 9.5 46.3 1.3 9.1 3.3 6.7 2 2 4 7 7 7 0 TATA element modulatory factor 1 DNA binding TSC22 PF01166.18 CDJ82115.1 - 1.2 9.6 35.3 0.054 13.8 1.3 7.0 5 1 2 7 7 7 0 TSC-22/dip/bun family Laminin_II PF06009.12 CDJ82115.1 - 1.3 9.1 29.7 0.35 10.9 8.4 4.5 2 1 3 5 5 5 0 Laminin Domain II PEARLI-4 PF05278.12 CDJ82115.1 - 1.3 8.5 27.5 0.02 14.5 2.3 3.7 2 2 1 3 3 3 0 Arabidopsis phospholipase-like protein (PEARLI 4) Prominin PF05478.11 CDJ82115.1 - 1.4 6.8 32.4 0.29 9.0 12.8 2.8 1 1 2 3 3 3 0 Prominin DUF4878 PF12870.7 CDJ82115.1 - 1.5 9.2 5.8 0.65 10.3 0.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4878) DUF812 PF05667.11 CDJ82115.1 - 1.6 7.5 49.8 0.3 9.9 8.4 4.0 1 1 1 3 3 3 0 Protein of unknown function (DUF812) SlyX PF04102.12 CDJ82115.1 - 1.8 9.3 52.2 0.29 11.8 5.3 7.1 3 2 4 7 7 6 0 SlyX Fib_alpha PF08702.10 CDJ82115.1 - 1.8 8.7 40.8 0.082 13.1 5.5 4.9 2 2 3 5 5 5 0 Fibrinogen alpha/beta chain family She9_MDM33 PF05546.11 CDJ82115.1 - 2.1 8.1 29.9 0.12 12.2 2.5 3.6 1 1 1 3 3 3 0 She9 / Mdm33 family DHR10 PF18595.1 CDJ82115.1 - 2.1 8.4 59.4 0.035 14.2 13.3 5.4 2 2 4 6 6 5 0 Designed helical repeat protein 10 domain Bacillus_HBL PF05791.11 CDJ82115.1 - 2.2 8.1 25.7 2.4 7.9 3.3 4.0 2 1 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) DUF4201 PF13870.6 CDJ82115.1 - 2.5 7.8 55.9 0.61 9.8 11.7 5.2 1 1 5 6 6 5 0 Domain of unknown function (DUF4201) DUF4600 PF15372.6 CDJ82115.1 - 3.9 7.9 38.7 0.58 10.6 8.1 3.8 2 2 1 3 3 3 0 Domain of unknown function (DUF4600) DUF1664 PF07889.12 CDJ82115.1 - 4.5 7.3 32.9 0.5 10.4 5.6 4.9 1 1 4 6 6 6 0 Protein of unknown function (DUF1664) DASH_Hsk3 PF08227.11 CDJ82115.1 - 4.8 7.6 12.4 8.2 6.9 0.1 4.7 3 1 1 4 4 4 0 DASH complex subunit Hsk3 like OmpH PF03938.14 CDJ82115.1 - 5.7 7.3 51.0 1.3 9.4 7.4 5.1 2 1 2 4 4 3 0 Outer membrane protein (OmpH-like) HOOK PF05622.12 CDJ82115.1 - 6.3 4.8 52.4 0.092 10.9 15.6 3.1 1 1 1 2 2 2 0 HOOK protein DUF4472 PF14739.6 CDJ82115.1 - 7.2 7.4 40.8 0.081 13.7 10.3 4.6 1 1 2 5 5 4 0 Domain of unknown function (DUF4472) CortBP2 PF09727.9 CDJ82115.1 - 8.6 6.2 45.7 0.041 13.8 17.3 2.9 1 1 2 3 3 2 0 Cortactin-binding protein-2 Seryl_tRNA_N PF02403.22 CDJ82115.1 - 9.8 6.5 43.8 0.45 10.8 9.0 5.3 1 1 3 5 5 5 0 Seryl-tRNA synthetase N-terminal domain EGF PF00008.27 CDJ82116.1 - 4.3e-10 39.7 16.2 2.8e-08 33.9 2.8 2.7 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 CDJ82116.1 - 8.8e-09 35.7 16.7 6.4e-06 26.6 2.4 3.0 3 0 0 3 3 3 2 Human growth factor-like EGF EGF_2 PF07974.13 CDJ82116.1 - 3.7e-07 30.4 22.4 0.00078 19.8 4.8 2.6 2 0 0 2 2 2 2 EGF-like domain Metallothio PF00131.20 CDJ82116.1 - 3.9 7.7 23.5 0.22 11.7 17.2 2.0 2 0 0 2 2 2 0 Metallothionein EGF PF00008.27 CDJ82117.1 - 4.3e-65 215.5 249.7 5.1e-07 29.9 8.0 19.6 19 0 0 19 19 19 19 EGF-like domain hEGF PF12661.7 CDJ82117.1 - 8.4e-32 108.7 210.2 5.7e-05 23.6 6.7 21.0 19 1 0 19 19 19 16 Human growth factor-like EGF Laminin_G_2 PF02210.24 CDJ82117.1 - 1.2e-27 97.0 0.7 5.2e-14 52.9 0.4 3.5 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.23 CDJ82117.1 - 6.9e-22 78.1 0.6 1.7e-11 44.4 0.1 4.5 4 1 0 4 4 4 3 Laminin G domain EGF_2 PF07974.13 CDJ82117.1 - 7.2e-20 71.1 285.8 0.017 15.5 11.0 19.8 19 1 0 19 19 19 16 EGF-like domain EGF_CA PF07645.15 CDJ82117.1 - 3.5e-05 23.9 11.7 3.5e-05 23.9 11.7 19.4 12 4 8 20 20 20 4 Calcium-binding EGF domain MrpF_PhaF PF04066.13 CDJ82118.1 - 0.2 12.0 5.7 8.6 6.8 0.1 4.4 4 0 0 4 4 4 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) CRAL_TRIO PF00650.20 CDJ82120.1 - 1.4e-28 99.6 0.1 2e-28 99.1 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain EMP70 PF02990.16 CDJ82121.1 - 2.2e-209 696.5 10.8 2.2e-209 696.5 10.8 1.6 2 0 0 2 2 2 1 Endomembrane protein 70 TFIID_30kDa PF03540.13 CDJ82122.1 - 0.0046 16.9 0.3 92 3.1 0.0 5.0 2 1 3 5 5 5 0 Transcription initiation factor TFIID 23-30kDa subunit ROKNT PF08067.11 CDJ82122.1 - 0.12 12.7 6.1 39 4.6 0.0 5.4 3 2 3 6 6 6 0 ROKNT (NUC014) domain FF PF01846.19 CDJ82122.1 - 0.34 11.1 1.9 59 4.0 0.1 4.7 6 0 0 6 6 6 0 FF domain Laminin_EGF PF00053.24 CDJ82123.1 - 0.00016 21.8 24.1 0.15 12.3 7.5 3.3 1 1 2 3 3 3 3 Laminin EGF domain EGF_2 PF07974.13 CDJ82123.1 - 0.017 15.4 23.5 0.058 13.8 3.1 3.4 3 0 0 3 3 3 0 EGF-like domain EGF PF00008.27 CDJ82123.1 - 7.9 6.9 20.6 3 8.2 2.5 3.5 3 1 0 3 3 3 0 EGF-like domain ASC PF00858.24 CDJ82124.1 - 3e-80 270.4 21.2 8.8e-80 268.8 21.2 1.6 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel Ribophorin_II PF05817.14 CDJ82125.1 - 1.3e-46 159.4 0.8 1.8e-46 159.0 0.8 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Metal_resist PF13801.6 CDJ82125.1 - 0.061 13.5 0.3 0.2 11.8 0.1 1.9 2 0 0 2 2 2 0 Heavy-metal resistance Ribosomal_L28 PF00830.19 CDJ82125.1 - 0.081 13.1 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 Ribosomal L28 family AMP-binding PF00501.28 CDJ82126.1 - 2.7e-87 293.1 0.0 3.6e-87 292.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ82126.1 - 8.7e-14 52.3 0.8 1.9e-13 51.2 0.8 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 CDJ82126.1 - 0.14 12.4 0.2 0.3 11.4 0.2 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain WW PF00397.26 CDJ82127.1 - 8.3e-09 35.4 1.9 2.1e-08 34.1 1.9 1.7 1 0 0 1 1 1 1 WW domain DUF1036 PF06282.11 CDJ82129.1 - 0.039 14.5 0.0 0.071 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1036) PgaD PF13994.6 CDJ82130.1 - 0.015 15.4 1.7 0.021 14.9 1.7 1.2 1 0 0 1 1 1 0 PgaD-like protein Kinesin PF00225.23 CDJ82131.1 - 2.6e-115 384.9 0.1 2.6e-115 384.9 0.1 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ82131.1 - 1.5e-26 93.2 0.1 1.5e-26 93.2 0.1 2.3 3 0 0 3 3 3 1 Microtubule binding DUF3694 PF12473.8 CDJ82131.1 - 3.9e-26 92.5 0.0 1.8e-24 87.1 0.0 2.9 2 1 0 2 2 2 1 Kinesin protein Kinesin_assoc PF16183.5 CDJ82131.1 - 2.5e-24 86.4 8.2 2.8e-17 63.4 0.8 3.3 2 1 1 3 3 3 2 Kinesin-associated KIF1B PF12423.8 CDJ82131.1 - 3.9e-16 59.2 0.0 1.1e-15 57.8 0.0 1.8 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.26 CDJ82131.1 - 0.00022 21.5 0.0 0.0013 19.0 0.0 2.4 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 CDJ82131.1 - 0.0031 17.8 0.0 0.01 16.2 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF1005 PF06219.12 CDJ82131.1 - 0.046 12.8 0.0 0.092 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1005) C2-C2_1 PF11618.8 CDJ82131.1 - 0.15 12.1 1.6 12 6.0 2.1 3.1 2 1 0 2 2 2 0 First C2 domain of RPGR-interacting protein 1 CorA PF01544.18 CDJ82131.1 - 0.16 11.3 3.6 0.4 10.0 3.6 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Lectin_N PF03954.14 CDJ82131.1 - 6.8 6.5 6.8 33 4.2 0.3 2.6 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Cgr1 PF03879.14 CDJ82131.1 - 9.2 6.7 9.3 28 5.1 9.3 1.8 1 0 0 1 1 1 0 Cgr1 family UDPGT PF00201.18 CDJ82132.1 - 8.8e-67 226.0 0.8 1.2e-66 225.6 0.8 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ82132.1 - 2.3e-10 40.7 0.0 3.9e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain NKWYS PF10364.9 CDJ82132.1 - 0.05 13.7 0.4 0.096 12.8 0.4 1.4 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein Glyco_transf_4 PF13439.6 CDJ82132.1 - 0.07 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 CDC48_2 PF02933.17 CDJ82132.1 - 0.15 11.9 0.0 0.65 9.8 0.0 2.0 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 GAIN_A PF18619.1 CDJ82133.1 - 0.14 12.3 1.6 0.29 11.4 1.6 1.5 1 0 0 1 1 1 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Carb_anhydrase PF00194.21 CDJ82134.1 - 2.7e-58 197.5 0.0 3.8e-58 197.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Patched PF02460.18 CDJ82135.1 - 3.7e-71 240.3 24.2 3.7e-71 240.3 24.2 2.2 2 1 0 2 2 2 1 Patched family NPC1_N PF16414.5 CDJ82135.1 - 5.4e-51 173.5 10.7 1.4e-50 172.2 10.7 1.7 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Sterol-sensing PF12349.8 CDJ82135.1 - 1.7e-39 135.1 4.3 1.7e-39 135.1 4.3 2.5 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Neurensin PF14927.6 CDJ82135.1 - 0.07 12.8 0.1 0.07 12.8 0.1 3.5 3 1 0 3 3 3 0 Neurensin Neur_chan_LBD PF02931.23 CDJ82136.1 - 0.042 13.3 1.5 0.053 13.0 1.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel ligand binding domain Sugar_tr PF00083.24 CDJ82137.1 - 5.9e-36 124.3 15.2 9.4e-36 123.6 15.2 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ82137.1 - 7.5e-14 51.4 29.4 3.8e-13 49.1 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF543 PF04418.12 CDJ82137.1 - 0.00039 20.3 2.1 0.037 14.0 0.0 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF543) Glyco_hydro_18 PF00704.28 CDJ82138.1 - 6.5e-92 308.6 1.0 8.8e-92 308.2 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 CDJ82138.1 - 1.1e-23 83.2 16.2 1.8e-12 47.2 5.6 2.5 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain DUF2093 PF09866.9 CDJ82138.1 - 2.6 7.5 4.4 2.8 7.5 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2093) Vitellogenin_N PF01347.22 CDJ82139.1 - 1.2e-92 311.3 0.4 1.8e-92 310.8 0.4 1.1 1 0 0 1 1 1 1 Lipoprotein amino terminal region DUF1943 PF09172.11 CDJ82139.1 - 9.4e-32 110.5 0.0 2e-31 109.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) VWD PF00094.25 CDJ82139.1 - 1.3e-11 45.0 0.1 3.4e-11 43.7 0.1 1.8 1 0 0 1 1 1 1 von Willebrand factor type D domain SKN1 PF03935.15 CDJ82139.1 - 0.18 10.2 0.0 0.29 9.5 0.0 1.2 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) YaeQ PF07152.12 CDJ82140.1 - 0.057 13.0 0.0 0.065 12.8 0.0 1.0 1 0 0 1 1 1 0 YaeQ protein ING PF12998.7 CDJ82141.1 - 5.1e-10 39.8 7.4 7.2e-10 39.4 7.4 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CDJ82141.1 - 1e-06 28.6 9.1 2.2e-06 27.5 9.1 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CDJ82141.1 - 0.0001 21.8 2.7 0.0001 21.8 2.7 2.0 2 0 0 2 2 2 1 PHD-finger Dor1 PF04124.12 CDJ82141.1 - 0.0067 15.1 3.3 0.0087 14.8 3.3 1.1 1 0 0 1 1 1 1 Dor1-like family SHE3 PF17078.5 CDJ82141.1 - 0.027 14.2 9.2 0.27 10.9 2.9 2.0 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 BLOC1_2 PF10046.9 CDJ82141.1 - 0.033 14.5 8.9 1.1 9.6 0.3 2.4 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fzo_mitofusin PF04799.13 CDJ82141.1 - 0.048 13.2 7.2 0.13 11.8 2.7 2.1 1 1 1 2 2 2 0 fzo-like conserved region AAA_13 PF13166.6 CDJ82141.1 - 0.072 11.7 3.8 0.082 11.5 3.8 1.1 1 0 0 1 1 1 0 AAA domain COG5 PF10392.9 CDJ82141.1 - 0.076 13.2 4.5 0.13 12.4 3.9 1.5 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DivIC PF04977.15 CDJ82141.1 - 0.18 11.6 3.6 4.1 7.3 0.7 2.7 2 1 1 3 3 3 0 Septum formation initiator DUF1195 PF06708.11 CDJ82141.1 - 0.22 11.3 2.2 0.4 10.4 1.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1195) MerR-DNA-bind PF09278.11 CDJ82141.1 - 0.25 11.9 5.2 0.29 11.7 0.4 2.4 2 1 0 2 2 2 0 MerR, DNA binding DUF4254 PF14063.6 CDJ82141.1 - 0.39 10.5 5.2 0.61 9.9 5.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4254) GyrB_insert PF18053.1 CDJ82141.1 - 0.43 10.4 4.6 3.3 7.6 2.8 2.0 1 1 1 2 2 2 0 DNA gyrase B subunit insert domain PhoU PF01895.19 CDJ82141.1 - 0.53 10.8 8.3 2.1 8.9 6.2 2.4 1 1 1 2 2 2 0 PhoU domain FlxA PF14282.6 CDJ82141.1 - 0.54 10.3 5.2 9.1 6.3 0.1 2.1 1 1 1 2 2 2 0 FlxA-like protein Cauli_AT PF03233.13 CDJ82141.1 - 0.74 9.7 6.3 0.79 9.6 0.5 2.5 1 1 1 2 2 2 0 Aphid transmission protein ABC_tran_CTD PF16326.5 CDJ82141.1 - 5.8 7.2 12.8 7.9 6.8 5.3 2.7 1 1 2 3 3 3 0 ABC transporter C-terminal domain PHD PF00628.29 CDJ82142.1 - 1.1e-06 28.4 5.7 2.6e-06 27.2 5.7 1.7 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CDJ82142.1 - 0.0062 16.8 1.5 0.017 15.4 1.5 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CDJ82142.1 - 0.071 13.3 0.9 0.16 12.2 0.9 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain PHD PF00628.29 CDJ82143.1 - 5.3e-05 23.0 4.8 0.00011 22.0 4.8 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CDJ82143.1 - 0.37 11.1 4.9 0.46 10.8 2.2 2.3 2 1 1 3 3 3 0 PHD-like zinc-binding domain Cadherin_C_2 PF16492.5 CDJ82144.1 - 0.033 14.9 0.7 0.25 12.1 0.0 2.3 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal RskA PF10099.9 CDJ82144.1 - 0.073 13.4 0.0 0.1 12.9 0.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA EphA2_TM PF14575.6 CDJ82144.1 - 0.12 13.3 0.2 0.43 11.5 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Synaphin PF05835.12 CDJ82145.1 - 2e-20 73.5 16.6 2.5e-20 73.2 16.6 1.1 1 0 0 1 1 1 1 Synaphin protein Tropomodulin PF03250.14 CDJ82145.1 - 0.011 15.8 3.9 0.013 15.6 3.9 1.1 1 0 0 1 1 1 0 Tropomodulin DUF1679 PF07914.11 CDJ82146.1 - 2.7e-35 122.1 0.1 3.7e-35 121.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 CDJ82146.1 - 9.3e-16 58.0 0.3 1.3e-14 54.2 0.3 2.5 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 CDJ82146.1 - 4.8e-13 49.6 0.0 7.2e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDJ82146.1 - 0.062 12.9 0.2 0.29 10.7 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase CBM_14 PF01607.24 CDJ82147.1 - 0 1059.5 455.4 1.8e-14 53.6 3.7 37.1 37 0 0 37 37 37 37 Chitin binding Peritrophin-A domain m_DGTX_Dc1a_b_c PF17491.2 CDJ82147.1 - 0.0034 18.0 50.4 1.6e+02 3.0 0.0 19.4 21 0 0 21 21 21 0 Spider Toxins mu-diguetoxin-1 a, b and c SprB PF13573.6 CDJ82147.1 - 0.31 10.9 26.4 1.2e+02 2.5 0.1 13.4 15 0 0 15 15 15 0 SprB repeat Troponin PF00992.20 CDJ82148.1 - 5.2e-05 23.6 8.1 5.2e-05 23.6 8.1 4.5 2 1 2 4 4 4 1 Troponin Ins_beta PF03488.14 CDJ82149.1 - 0.012 15.6 3.2 0.012 15.6 3.2 2.2 2 1 1 3 3 3 0 Nematode insulin-related peptide beta type Insulin PF00049.18 CDJ82149.1 - 0.05 14.6 5.9 0.074 14.1 5.9 1.6 1 1 0 1 1 1 0 Insulin/IGF/Relaxin family Cucumo_coat PF00760.18 CDJ82150.1 - 0.032 13.9 6.5 5.6 6.6 0.2 4.0 1 1 3 4 4 4 0 Cucumovirus coat protein DUF1254 PF06863.12 CDJ82150.1 - 0.11 12.6 0.4 10 6.2 0.0 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF1254) DUF1254 PF06863.12 CDJ82151.1 - 0.0015 18.6 3.2 8.3 6.5 0.0 4.8 2 1 3 5 5 5 1 Protein of unknown function (DUF1254) DUF2470 PF10615.9 CDJ82151.1 - 0.12 13.1 0.6 68 4.2 0.3 3.9 2 2 0 2 2 2 0 Protein of unknown function (DUF2470) Cucumo_coat PF00760.18 CDJ82151.1 - 0.17 11.5 4.7 8.3 6.0 1.6 3.1 1 1 1 2 2 2 0 Cucumovirus coat protein HSP20 PF00011.21 CDJ82153.1 - 7.1e-13 48.6 0.0 1.1e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Hjc PF01870.18 CDJ82153.1 - 0.04 13.9 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) PapA_C PF16911.5 CDJ82153.1 - 0.19 11.8 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus LRR_4 PF12799.7 CDJ82154.1 - 9.3e-12 45.0 10.1 0.0031 17.9 0.0 5.8 5 1 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ82154.1 - 1.1e-10 41.1 21.4 0.00012 21.8 0.7 5.7 4 2 0 4 4 4 3 Leucine rich repeat Ig_3 PF13927.6 CDJ82154.1 - 2.1e-05 25.0 0.0 6e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 CDJ82154.1 - 0.00077 19.5 0.0 0.0022 18.0 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_1 PF00560.33 CDJ82154.1 - 0.0026 18.1 13.2 34 5.5 0.3 7.6 7 1 0 7 7 6 0 Leucine Rich Repeat DUF3584 PF12128.8 CDJ82154.1 - 0.026 12.1 12.7 0.035 11.6 12.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) LRR_6 PF13516.6 CDJ82154.1 - 0.041 13.9 14.2 49 4.3 0.1 7.4 7 0 0 7 7 7 0 Leucine Rich repeat F-box_4 PF15966.5 CDJ82154.1 - 0.064 13.1 3.4 0.65 9.9 0.8 2.6 2 0 0 2 2 2 0 F-box Prominin PF05478.11 CDJ82154.1 - 0.4 8.6 4.2 0.65 7.9 4.2 1.2 1 0 0 1 1 1 0 Prominin FAM184 PF15665.5 CDJ82154.1 - 0.41 10.4 15.8 0.095 12.5 12.4 1.6 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B LRR_9 PF14580.6 CDJ82154.1 - 0.81 9.2 5.7 0.62 9.6 0.3 2.9 2 1 1 3 3 3 0 Leucine-rich repeat Apolipoprotein PF01442.18 CDJ82154.1 - 2 8.2 19.5 13 5.7 18.9 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Phage_Mu_Gam PF07352.12 CDJ82154.1 - 4.2 7.3 7.8 1.4e+02 2.3 7.8 2.3 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF883 PF05957.13 CDJ82154.1 - 5 7.8 9.4 13 6.5 0.6 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Ribosomal_S18 PF01084.20 CDJ82155.1 - 3.7e-15 55.9 0.0 9.3e-15 54.6 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S18 WD40 PF00400.32 CDJ82156.1 - 5.4e-12 46.0 16.8 0.0045 17.8 0.1 7.2 6 1 1 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ82156.1 - 2.9e-10 40.3 1.4 0.026 14.8 0.1 5.0 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDJ82156.1 - 0.00014 21.8 1.2 0.0025 17.7 0.1 2.9 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 CDJ82156.1 - 1.3 6.9 4.5 2.6 5.9 2.1 2.4 2 1 0 2 2 2 0 IKI3 family JAB PF01398.21 CDJ82157.1 - 2.6e-32 111.3 0.0 5.5e-32 110.2 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CDJ82157.1 - 4.5e-15 56.0 0.5 9.1e-15 55.1 0.5 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 CDJ82157.1 - 4.8e-06 26.3 0.0 7.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain RNA_pol_Rpb1_7 PF04990.12 CDJ82160.1 - 2.7e-20 72.7 0.1 4e-20 72.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_5 PF04998.17 CDJ82160.1 - 1.2e-07 31.4 0.0 1.3e-07 31.4 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 MPC PF03650.13 CDJ82161.1 - 1.9e-09 37.6 0.3 2.2e-09 37.5 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MPLKIP PF15502.6 CDJ82162.1 - 0.0042 17.3 2.0 0.0042 17.3 2.0 2.0 2 1 0 2 2 2 1 M-phase-specific PLK1-interacting protein Pkinase PF00069.25 CDJ82163.1 - 1.2e-72 244.5 0.0 1.6e-72 244.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ82163.1 - 3.3e-32 111.8 0.0 4.9e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ82163.1 - 6.9e-09 35.1 0.1 1.2e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CDJ82163.1 - 0.0013 18.1 0.0 0.0065 15.8 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDJ82163.1 - 0.029 13.7 0.2 0.06 12.7 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ82163.1 - 0.03 14.3 0.1 1.1 9.2 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ82163.1 - 0.079 11.7 0.0 0.079 11.7 0.0 2.5 2 1 0 2 2 2 0 Fungal protein kinase Nebulin PF00880.18 CDJ82165.1 - 1.7e-19 69.3 4.4 1.2e-12 47.4 0.4 2.7 2 0 0 2 2 2 2 Nebulin repeat LIM PF00412.22 CDJ82165.1 - 6.5e-12 45.5 6.4 1.1e-11 44.8 6.4 1.4 1 0 0 1 1 1 1 LIM domain Y_phosphatase PF00102.27 CDJ82167.1 - 1.9e-56 191.3 2.2 4.4e-42 144.3 2.8 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase TauD PF02668.16 CDJ82168.1 - 7.8e-09 35.7 0.0 9.2e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family HIG_1_N PF04588.13 CDJ82169.1 - 3.2e-13 49.7 1.0 6.1e-13 48.8 1.0 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region MgtC PF02308.16 CDJ82169.1 - 0.054 13.9 0.4 0.072 13.5 0.4 1.2 1 0 0 1 1 1 0 MgtC family UNC-50 PF05216.13 CDJ82169.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 UNC-50 family TauD PF02668.16 CDJ82170.1 - 9.3e-25 87.9 0.1 1.3e-24 87.4 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1075 PF06388.11 CDJ82171.1 - 0.01 15.9 0.0 0.018 15.1 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1075) HIG_1_N PF04588.13 CDJ82172.1 - 2.6e-13 50.0 3.6 3.6e-13 49.5 3.6 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF3784 PF12650.7 CDJ82175.1 - 0.0064 16.7 0.2 0.0064 16.7 0.2 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3784) Mito_fiss_reg PF05308.11 CDJ82175.1 - 0.83 9.7 11.8 1.2 9.1 11.8 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Flp_Fap PF04964.14 CDJ82176.1 - 0.033 14.0 0.4 0.052 13.4 0.4 1.2 1 0 0 1 1 1 0 Flp/Fap pilin component HLH PF00010.26 CDJ82177.1 - 1.5e-16 60.1 0.8 1.5e-16 60.1 0.8 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4124 PF13511.6 CDJ82177.1 - 0.062 13.6 0.5 0.12 12.7 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) Snapin_Pallidin PF14712.6 CDJ82177.1 - 0.15 12.5 0.6 0.26 11.7 0.6 1.4 1 0 0 1 1 1 0 Snapin/Pallidin HORMA PF02301.18 CDJ82178.1 - 1.5e-25 90.0 1.0 2.2e-25 89.5 1.0 1.2 1 0 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 CDJ82178.1 - 0.00063 19.6 0.1 0.0012 18.8 0.1 1.5 2 0 0 2 2 2 1 Bacterial HORMA domain 2 Imm35 PF15567.6 CDJ82178.1 - 0.17 12.1 0.1 0.33 11.1 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 35 DnaJ PF00226.31 CDJ82179.1 - 1.3e-15 57.3 0.3 1.3e-15 57.3 0.3 2.9 3 0 0 3 3 3 1 DnaJ domain Myb_DNA-binding PF00249.31 CDJ82179.1 - 2.7e-10 40.3 8.7 4.7e-07 29.9 0.1 3.8 4 0 0 4 4 4 2 Myb-like DNA-binding domain RAC_head PF16717.5 CDJ82179.1 - 1.6e-08 35.4 5.9 1.6e-08 35.4 5.9 3.8 2 2 0 2 2 2 1 Ribosome-associated complex head domain Myb_DNA-bind_6 PF13921.6 CDJ82179.1 - 9.2e-07 29.0 2.0 0.0028 17.9 0.4 3.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUP PF00674.18 CDJ82179.1 - 0.0029 17.7 0.9 2.8 8.1 0.1 2.6 2 0 0 2 2 2 2 DUP family SRP54 PF00448.22 CDJ82179.1 - 0.15 11.7 1.3 0.18 11.4 0.1 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Hid1 PF12722.7 CDJ82179.1 - 2.4 6.2 16.6 3.3 5.7 16.6 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ank_2 PF12796.7 CDJ82180.1 - 1.5e-27 96.0 0.8 6.8e-17 61.8 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ82180.1 - 2.6e-24 85.2 2.5 5.3e-09 36.4 0.1 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 CDJ82180.1 - 2.1e-23 81.6 5.3 3.7e-07 30.3 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 CDJ82180.1 - 3.8e-22 76.0 0.2 4e-05 23.7 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 CDJ82180.1 - 3.8e-17 62.1 1.9 2.7e-08 33.9 0.0 3.8 2 1 0 3 3 3 3 Ankyrin repeats (many copies) SAM_1 PF00536.30 CDJ82180.1 - 1.1e-09 38.6 0.0 2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF2520 PF10728.9 CDJ82180.1 - 0.015 15.1 0.5 0.33 10.7 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF2520) SAM_2 PF07647.17 CDJ82180.1 - 0.032 14.3 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) ABC_membrane_2 PF06472.15 CDJ82181.1 - 5.2e-54 183.5 6.3 7.1e-54 183.0 6.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CDJ82181.1 - 7.4e-15 55.7 0.0 1.2e-14 55.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 CDJ82181.1 - 0.00053 20.4 0.0 0.0012 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 CDJ82181.1 - 0.0093 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 CDJ82181.1 - 0.046 13.4 0.1 6.5 6.4 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 CDJ82181.1 - 0.065 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 CDJ82181.1 - 0.07 13.4 0.4 0.22 11.8 0.3 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CDJ82181.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 CDJ82181.1 - 0.11 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2492 PF10678.9 CDJ82181.1 - 0.14 12.4 0.0 9.1 6.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2492) DUF4352 PF11611.8 CDJ82181.1 - 0.17 12.2 0.0 0.42 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4352) AAA_18 PF13238.6 CDJ82181.1 - 0.18 12.4 0.0 0.36 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arfaptin PF06456.13 CDJ82182.1 - 4.4e-27 95.1 1.8 5.6e-27 94.8 1.8 1.1 1 0 0 1 1 1 1 Arfaptin-like domain Neur_chan_LBD PF02931.23 CDJ82184.1 - 4.9e-42 143.8 0.1 6.5e-42 143.4 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ82184.1 - 1.1e-21 78.0 2.3 1.9e-17 64.1 0.1 2.7 3 0 0 3 3 3 2 Neurotransmitter-gated ion-channel transmembrane region DUF4574 PF15141.6 CDJ82185.1 - 0.075 12.9 0.1 3.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 LPP PF04728.13 CDJ82185.1 - 0.19 12.2 2.3 0.34 11.3 2.3 1.4 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Lectin_C PF00059.21 CDJ82186.1 - 2.6e-14 53.8 11.0 3.4e-14 53.5 11.0 1.2 1 0 0 1 1 1 1 Lectin C-type domain MULE PF10551.9 CDJ82186.1 - 0.05 14.0 0.0 0.14 12.6 0.0 1.7 1 1 1 2 2 2 0 MULE transposase domain tRNA-synt_1g PF09334.11 CDJ82188.1 - 2.2e-149 497.5 1.0 3.1e-149 497.0 1.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA_bind PF01588.20 CDJ82188.1 - 1e-31 108.9 0.2 2.1e-31 107.9 0.2 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1 PF00133.22 CDJ82188.1 - 4.5e-09 35.1 0.1 1.6e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDJ82188.1 - 0.00078 19.4 0.0 0.002 18.1 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CDJ82188.1 - 0.068 12.5 0.0 0.43 9.9 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain zinc-ribbons_6 PF07191.12 CDJ82188.1 - 2.7 8.0 7.0 10 6.2 6.9 2.0 1 1 0 1 1 1 0 zinc-ribbons zf-C2HC5 PF06221.13 CDJ82188.1 - 4.4 7.4 6.4 14 5.7 1.1 2.5 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type NUC153 PF08159.12 CDJ82189.1 - 5.9e-06 26.0 5.6 9.2e-06 25.4 0.0 3.4 3 0 0 3 3 3 1 NUC153 domain SIR2 PF02146.17 CDJ82190.1 - 1.3e-22 80.5 0.0 6.7e-15 55.5 0.0 2.7 2 1 1 3 3 3 2 Sir2 family TPP_enzyme_M PF00205.22 CDJ82190.1 - 0.0013 18.5 0.0 0.037 13.8 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Ribosomal_S17_N PF16205.5 CDJ82192.1 - 1e-28 99.5 0.1 1.9e-28 98.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 CDJ82192.1 - 5.3e-25 87.3 0.2 7.8e-25 86.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Mtc PF03820.17 CDJ82193.1 - 1.6e-131 438.0 0.3 1.8e-131 437.8 0.3 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier ARD PF03079.14 CDJ82194.1 - 6.9e-53 179.0 0.1 7.7e-53 178.9 0.1 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 CDJ82194.1 - 0.0069 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain EutQ PF06249.12 CDJ82194.1 - 0.095 12.5 0.0 0.13 12.0 0.0 1.3 1 1 0 1 1 1 0 Ethanolamine utilisation protein EutQ Kunitz_BPTI PF00014.23 CDJ82195.1 - 1.2e-17 63.9 2.6 1.4e-17 63.7 2.6 1.1 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Glyco_transf_11 PF01531.16 CDJ82196.1 - 3e-06 26.7 3.4 6.7e-05 22.2 3.4 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 11 O-FucT PF10250.9 CDJ82196.1 - 0.0065 16.2 0.0 0.025 14.3 0.0 1.9 1 1 1 2 2 2 1 GDP-fucose protein O-fucosyltransferase OST-HTH PF12872.7 CDJ82196.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 OST-HTH/LOTUS domain Snf7 PF03357.21 CDJ82197.1 - 1.6e-38 132.0 6.0 2.3e-38 131.5 6.0 1.2 1 0 0 1 1 1 1 Snf7 DUF1024 PF06260.12 CDJ82197.1 - 0.021 15.1 1.2 1.3 9.3 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1024) UvrC_HhH_N PF08459.11 CDJ82197.1 - 0.055 13.4 0.3 0.07 13.0 0.3 1.3 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal SLX9 PF15341.6 CDJ82197.1 - 0.38 11.2 11.8 1.3 9.4 11.8 2.0 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 CTNNB1_binding PF08347.11 CDJ82198.1 - 0.013 15.7 0.4 0.016 15.4 0.4 1.1 1 0 0 1 1 1 0 N-terminal CTNNB1 binding Ribosomal_S26e PF01283.19 CDJ82199.1 - 6.4e-50 168.1 9.5 2.5e-49 166.2 9.5 2.1 1 0 0 1 1 1 1 Ribosomal protein S26e DnaJ PF00226.31 CDJ82199.1 - 1e-26 92.8 1.3 1.9e-26 92.0 1.3 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 CDJ82199.1 - 6.3e-17 62.0 0.0 3.3e-16 59.7 0.0 1.9 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CDJ82199.1 - 3.3e-14 53.0 15.1 3.3e-14 53.0 15.1 2.4 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 CDJ82199.1 - 5.1 7.1 22.0 0.2 11.7 1.9 2.8 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein 7tm_3 PF00003.22 CDJ82201.1 - 3e-31 109.0 11.8 3.9e-31 108.6 11.8 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Neur_chan_LBD PF02931.23 CDJ82202.1 - 1.1e-45 155.8 0.8 1.5e-45 155.3 0.8 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ82202.1 - 3.6e-30 105.8 2.2 6e-30 105.1 0.2 2.1 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region MFS_Mycoplasma PF07672.13 CDJ82202.1 - 0.016 14.5 0.2 0.14 11.4 0.3 2.0 1 1 1 2 2 2 0 Mycoplasma MFS transporter Neur_chan_LBD PF02931.23 CDJ82203.1 - 1.5e-45 155.3 1.1 2.1e-45 154.8 1.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ82203.1 - 1.9e-29 103.4 0.7 4.3e-26 92.4 0.1 2.3 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region 7tm_1 PF00001.21 CDJ82204.1 - 3.4e-14 52.8 29.5 4.6e-14 52.4 29.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1505 PF07403.11 CDJ82204.1 - 0.068 13.4 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1505) HTH_29 PF13551.6 CDJ82205.1 - 1e-12 47.9 1.5 9.2e-11 41.6 0.5 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 CDJ82205.1 - 2.6e-12 46.2 1.0 2.8e-09 36.5 0.1 2.4 2 0 0 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.6 CDJ82205.1 - 8.7e-11 41.8 0.2 4.1e-07 30.0 0.1 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain MarR_2 PF12802.7 CDJ82205.1 - 1.2e-06 28.3 0.4 0.00031 20.6 0.1 2.3 1 1 1 2 2 2 1 MarR family HTH_38 PF13936.6 CDJ82205.1 - 1.8e-06 27.6 1.5 0.0026 17.5 0.1 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain DUF4423 PF14394.6 CDJ82205.1 - 6e-06 26.1 0.9 7.3e-06 25.8 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_Crp_2 PF13545.6 CDJ82205.1 - 1.4e-05 25.0 1.5 0.00018 21.4 0.2 2.2 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain HTH_32 PF13565.6 CDJ82205.1 - 2.7e-05 24.7 2.6 5.1e-05 23.8 2.2 1.7 1 1 1 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 CDJ82205.1 - 3.2e-05 23.9 0.1 0.03 14.4 0.1 2.7 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_11 PF08279.12 CDJ82205.1 - 7.1e-05 22.7 0.9 0.038 13.9 0.0 2.6 3 0 0 3 3 2 1 HTH domain HTH_Tnp_ISL3 PF13542.6 CDJ82205.1 - 9.2e-05 21.8 0.3 0.12 11.8 0.1 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_IS630 PF01710.16 CDJ82205.1 - 9.9e-05 22.4 1.0 0.00012 22.1 1.0 1.2 1 0 0 1 1 1 1 Transposase TrmB PF01978.19 CDJ82205.1 - 0.00012 21.9 0.5 0.0023 17.8 0.1 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 CDJ82205.1 - 0.00015 21.3 0.4 0.021 14.4 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding CENP-B_N PF04218.13 CDJ82205.1 - 0.00017 21.1 1.4 0.13 11.9 0.1 2.6 2 1 0 2 2 2 2 CENP-B N-terminal DNA-binding domain MarR PF01047.22 CDJ82205.1 - 0.0002 21.2 0.3 0.091 12.7 0.0 2.3 2 0 0 2 2 2 1 MarR family HTH_psq PF05225.16 CDJ82205.1 - 0.00054 19.7 0.0 0.0013 18.4 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_35 PF13693.6 CDJ82205.1 - 0.00065 19.7 0.2 0.15 12.1 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_17 PF12728.7 CDJ82205.1 - 0.00069 19.8 0.1 1.6 9.0 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_AsnC-type PF13404.6 CDJ82205.1 - 0.0008 19.2 0.1 1.3 8.9 0.0 2.3 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain PAX PF00292.18 CDJ82205.1 - 0.00096 19.1 0.4 0.0013 18.6 0.4 1.3 1 1 0 1 1 1 1 'Paired box' domain Terminase_5 PF06056.12 CDJ82205.1 - 0.0014 18.4 0.2 0.012 15.5 0.0 2.3 3 0 0 3 3 2 1 Putative ATPase subunit of terminase (gpP-like) HTH_26 PF13443.6 CDJ82205.1 - 0.0029 18.0 0.5 2.1 8.9 0.0 2.3 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain HTH_36 PF13730.6 CDJ82205.1 - 0.0032 17.4 0.2 1.4 8.9 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_18 PF12833.7 CDJ82205.1 - 0.0035 17.6 0.0 0.052 13.8 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 CDJ82205.1 - 0.0045 16.5 3.2 0.055 13.0 0.2 2.8 2 1 1 3 3 3 1 Sigma-70, region 4 HTH_IclR PF09339.10 CDJ82205.1 - 0.005 16.6 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_27 PF13463.6 CDJ82205.1 - 0.0068 16.9 1.1 0.026 15.0 0.3 2.0 1 1 1 2 2 2 1 Winged helix DNA-binding domain DUF1018 PF06252.12 CDJ82205.1 - 0.014 16.3 1.5 0.018 16.0 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) HTH_6 PF01418.17 CDJ82205.1 - 0.016 15.1 0.0 0.19 11.8 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family FeoC PF09012.10 CDJ82205.1 - 0.017 15.2 0.9 0.23 11.6 0.0 2.1 2 0 0 2 2 2 0 FeoC like transcriptional regulator HTH_10 PF04967.12 CDJ82205.1 - 0.023 14.5 0.9 0.74 9.7 0.0 2.6 3 0 0 3 3 2 0 HTH DNA binding domain Mga PF05043.13 CDJ82205.1 - 0.023 15.2 0.2 0.13 12.9 0.0 2.0 2 0 0 2 2 2 0 Mga helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 CDJ82205.1 - 0.026 14.4 2.5 0.042 13.7 0.3 2.0 2 0 0 2 2 2 0 Tc3 transposase Rrf2 PF02082.20 CDJ82205.1 - 0.028 14.8 0.4 3.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator Sigma70_r4_2 PF08281.12 CDJ82205.1 - 0.032 13.9 0.8 1.5 8.5 0.1 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 UPF0122 PF04297.14 CDJ82205.1 - 0.058 13.6 0.3 4.1 7.7 0.0 2.4 2 1 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like DUF4817 PF16087.5 CDJ82205.1 - 0.08 12.8 0.4 1.3 8.8 0.1 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain (DUF4817) HU-CCDC81_euk_2 PF18289.1 CDJ82205.1 - 0.097 12.8 0.0 6.4 7.0 0.0 2.2 2 0 0 2 2 2 0 CCDC81 eukaryotic HU domain 2 GntR PF00392.21 CDJ82205.1 - 0.23 11.1 2.1 10 5.8 0.1 3.1 3 1 0 3 3 2 0 Bacterial regulatory proteins, gntR family TMEM154 PF15102.6 CDJ82206.1 - 1.1e-05 25.4 0.0 2.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family OAD_gamma PF04277.13 CDJ82206.1 - 0.00011 22.7 0.1 0.00011 22.7 0.1 2.1 2 0 0 2 2 2 1 Oxaloacetate decarboxylase, gamma chain BatD PF13584.6 CDJ82206.1 - 0.0042 16.0 0.0 0.0072 15.2 0.0 1.3 1 0 0 1 1 1 1 Oxygen tolerance Rax2 PF12768.7 CDJ82206.1 - 0.0056 16.2 0.0 0.0075 15.8 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity EphA2_TM PF14575.6 CDJ82206.1 - 0.034 15.0 0.0 0.069 14.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Phage_holin_3_6 PF07332.11 CDJ82206.1 - 0.036 14.1 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Syndecan PF01034.20 CDJ82206.1 - 0.04 13.8 0.5 0.085 12.8 0.5 1.6 1 0 0 1 1 1 0 Syndecan domain TMEM51 PF15345.6 CDJ82206.1 - 0.041 13.7 0.5 0.082 12.7 0.0 1.7 2 0 0 2 2 2 0 Transmembrane protein 51 DUF2207 PF09972.9 CDJ82206.1 - 0.043 12.6 0.0 0.055 12.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Orf78 PF06024.12 CDJ82206.1 - 0.047 14.0 0.0 0.095 13.0 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Shisa PF13908.6 CDJ82206.1 - 0.072 13.3 0.4 0.35 11.1 0.0 2.0 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator RIFIN PF02009.16 CDJ82206.1 - 0.11 12.4 0.1 0.15 11.9 0.1 1.1 1 0 0 1 1 1 0 Rifin DUF1180 PF06679.12 CDJ82206.1 - 0.14 12.6 0.0 0.14 12.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) SIT PF15330.6 CDJ82206.1 - 0.18 12.3 0.0 0.51 10.8 0.0 1.7 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT NfeD PF01957.18 CDJ82206.1 - 1.4 9.4 4.3 11 6.4 4.3 2.2 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding KH_1 PF00013.29 CDJ82207.1 - 4e-19 68.2 0.2 4.1e-14 52.1 0.1 3.7 4 0 0 4 4 4 3 KH domain SLS PF14611.6 CDJ82207.1 - 9.4e-05 22.3 1.0 0.052 13.4 0.1 2.4 2 0 0 2 2 2 2 Mitochondrial inner-membrane-bound regulator KH_10 PF17905.1 CDJ82207.1 - 0.016 15.6 2.7 0.94 10.0 0.1 4.4 5 1 1 6 6 6 0 GLD-3 KH domain 5 Armet PF10208.9 CDJ82208.1 - 2.9e-60 202.4 11.1 3.5e-60 202.1 11.1 1.0 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding DZR PF12773.7 CDJ82208.1 - 2.1 8.4 6.6 8.3 6.5 1.4 3.1 1 1 1 2 2 2 0 Double zinc ribbon UQ_con PF00179.26 CDJ82209.1 - 1.2e-48 164.3 0.0 1.4e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ82209.1 - 0.0035 17.0 0.0 0.0044 16.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CDJ82209.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 CDJ82209.1 - 0.04 14.2 0.1 0.062 13.6 0.1 1.5 1 1 0 1 1 1 0 RWD domain Bap31 PF05529.12 CDJ82210.1 - 1.1e-40 138.6 2.3 1.5e-40 138.1 2.3 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 CDJ82210.1 - 2.8e-11 43.2 3.7 2.8e-11 43.2 3.7 1.6 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain DUF3584 PF12128.8 CDJ82210.1 - 0.0014 16.2 0.3 0.0019 15.9 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.9 CDJ82210.1 - 0.0029 17.6 4.6 0.0048 16.9 4.6 1.3 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 CDJ82210.1 - 0.003 17.2 0.7 0.0042 16.7 0.7 1.2 1 0 0 1 1 1 1 Intermediate filament protein FlxA PF14282.6 CDJ82210.1 - 0.027 14.5 0.5 0.064 13.2 0.5 1.6 1 1 0 1 1 1 0 FlxA-like protein Tropomyosin_1 PF12718.7 CDJ82210.1 - 0.055 13.6 3.2 0.084 13.0 3.2 1.3 1 0 0 1 1 1 0 Tropomyosin like DUF4337 PF14235.6 CDJ82210.1 - 0.15 12.2 3.4 0.23 11.6 2.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) Seryl_tRNA_N PF02403.22 CDJ82210.1 - 0.29 11.4 3.2 0.48 10.7 3.2 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Phage_holin_6_1 PF09682.10 CDJ82210.1 - 0.38 11.2 2.0 0.45 11.0 0.0 2.1 2 1 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DivIC PF04977.15 CDJ82210.1 - 0.88 9.4 4.1 0.92 9.3 2.1 2.0 1 1 1 2 2 2 0 Septum formation initiator APG6_N PF17675.1 CDJ82210.1 - 1.1 9.8 6.1 2.3 8.8 6.1 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region UQ_con PF00179.26 CDJ82211.1 - 1.9e-37 128.0 0.0 2.3e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF676 PF05057.14 CDJ82212.1 - 1.3e-41 142.5 0.0 2.1e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 CDJ82212.1 - 5.3e-07 29.7 0.0 7.9e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 CDJ82212.1 - 2.7e-05 24.0 0.0 0.00022 21.0 0.0 2.1 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 CDJ82212.1 - 9.2e-05 23.1 0.1 0.00016 22.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDJ82212.1 - 0.0028 17.0 0.1 0.0091 15.3 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LCAT PF02450.15 CDJ82212.1 - 0.18 10.9 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase NOB1_Zn_bind PF08772.11 CDJ82213.1 - 2.9e-28 97.8 0.2 5.4e-28 97.0 0.2 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 CDJ82213.1 - 7.5e-26 90.5 0.2 1.9e-25 89.2 0.1 1.7 2 0 0 2 2 2 1 PIN domain of ribonuclease RNA_POL_M_15KD PF02150.16 CDJ82213.1 - 0.0026 17.6 0.1 0.033 14.0 0.0 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit zf-RING_2 PF13639.6 CDJ82214.1 - 6.9e-10 39.1 8.0 6.9e-10 39.1 8.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CDJ82214.1 - 1.5e-07 31.6 6.5 1.5e-07 31.6 6.5 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zinc_ribbon_9 PF14369.6 CDJ82214.1 - 6.3e-07 29.5 1.3 6.3e-07 29.5 1.3 3.0 3 0 0 3 3 3 1 zinc-ribbon zf-C3HC4_2 PF13923.6 CDJ82214.1 - 1.5e-06 27.9 8.2 1.5e-06 27.9 8.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDJ82214.1 - 4.3e-06 26.7 3.0 4.3e-06 26.7 3.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CDJ82214.1 - 9.8e-05 22.3 3.2 9.8e-05 22.3 3.2 2.8 2 2 2 4 4 4 1 RING-type zinc-finger zf-RING_11 PF17123.5 CDJ82214.1 - 0.00012 21.8 6.2 0.00012 21.8 6.2 2.8 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 CDJ82214.1 - 0.00019 21.2 4.0 0.00019 21.2 4.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ82214.1 - 0.00037 20.4 14.3 0.00039 20.3 5.9 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CDJ82214.1 - 0.0013 18.6 6.5 0.0013 18.6 6.5 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CDJ82214.1 - 0.008 15.8 5.3 0.008 15.8 5.3 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type HypA PF01155.19 CDJ82214.1 - 0.13 12.3 6.0 0.59 10.2 0.3 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Prok-RING_4 PF14447.6 CDJ82214.1 - 0.38 10.6 14.2 0.038 13.9 7.2 2.6 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Zn_ribbon_SprT PF17283.2 CDJ82214.1 - 1.5 8.8 8.5 26 4.9 4.8 3.3 2 1 0 2 2 2 0 SprT-like zinc ribbon domain zinc-ribbons_6 PF07191.12 CDJ82214.1 - 2.2 8.3 11.4 2 8.5 0.3 3.1 2 1 1 3 3 3 0 zinc-ribbons FANCL_C PF11793.8 CDJ82214.1 - 2.3 8.4 8.3 9.5 6.5 6.0 2.9 2 1 0 2 2 2 0 FANCL C-terminal domain DZR PF12773.7 CDJ82214.1 - 8.5 6.5 10.5 1.4 9.0 0.6 2.9 2 1 0 2 2 2 0 Double zinc ribbon Peptidase_S24 PF00717.23 CDJ82215.1 - 7.9e-10 38.6 0.1 1.3e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like S1 PF00575.23 CDJ82216.1 - 5.4e-15 55.5 0.0 8.8e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 CDJ82216.1 - 3.2e-14 53.0 0.0 6.6e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.12 CDJ82216.1 - 0.00075 19.7 0.0 0.0012 19.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 rve PF00665.26 CDJ82217.1 - 0.0047 17.1 0.0 0.015 15.5 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 CDJ82217.1 - 0.056 13.2 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain 7TM_GPCR_Srv PF10323.9 CDJ82220.1 - 7.2e-13 48.5 6.6 8.4e-13 48.3 6.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Srg PF02118.21 CDJ82220.1 - 4.3e-08 33.2 7.8 4.9e-08 33.0 7.8 1.0 1 0 0 1 1 1 1 Srg family chemoreceptor 7tm_1 PF00001.21 CDJ82220.1 - 9.9e-06 25.1 6.3 1.6e-05 24.4 6.0 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CDJ82220.1 - 2.2e-05 24.2 7.5 4.3e-05 23.3 7.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx PhoLip_ATPase_C PF16212.5 CDJ82220.1 - 0.35 10.6 9.6 1.8 8.2 7.9 2.1 1 1 1 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal 7TM_GPCR_Srv PF10323.9 CDJ82221.1 - 2.7e-11 43.4 8.8 4e-06 26.4 5.4 2.0 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv Ac76 PF05814.11 CDJ82221.1 - 0.019 14.9 0.2 6.3 6.9 0.0 2.4 2 0 0 2 2 2 0 Orf76 (Ac76) CX PF01705.19 CDJ82222.1 - 5.4e-07 30.1 8.9 6.2e-06 26.7 1.1 2.7 3 0 0 3 3 3 2 CX module Myc_target_1 PF15179.6 CDJ82222.1 - 0.015 15.2 0.4 0.023 14.6 0.4 1.3 1 0 0 1 1 1 0 Myc target protein 1 zf-C2H2_2 PF12756.7 CDJ82223.1 - 0.0067 16.7 0.1 0.011 16.1 0.1 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 CDJ82223.1 - 0.022 15.2 0.5 0.051 14.0 0.5 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 CDJ82223.1 - 0.08 13.3 0.6 0.17 12.2 0.6 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding 7TM_GPCR_Sra PF02117.16 CDJ82224.1 - 3.5e-06 26.1 3.2 4.8e-06 25.7 3.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sra 7TM_GPCR_Srb PF02175.16 CDJ82224.1 - 0.00013 21.8 4.5 0.00013 21.8 4.5 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srb 7TM_GPCR_Srab PF10292.9 CDJ82225.1 - 4.7e-08 32.3 10.8 7.2e-06 25.1 5.1 2.0 1 1 1 2 2 2 2 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Sra PF02117.16 CDJ82225.1 - 0.0087 14.9 9.4 0.023 13.5 9.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sra 7TM_GPCR_Srx PF10328.9 CDJ82226.1 - 9e-07 28.8 13.6 1.4e-06 28.2 13.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 CDJ82226.1 - 0.0002 20.7 9.8 0.0002 20.7 9.8 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Srg PF02118.21 CDJ82226.1 - 0.0021 17.8 19.4 0.0049 16.6 18.8 1.7 1 1 0 1 1 1 1 Srg family chemoreceptor LapA_dom PF06305.11 CDJ82226.1 - 0.11 12.3 0.0 0.36 10.7 0.0 1.9 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain 7TM_GPCR_Srb PF02175.16 CDJ82229.1 - 3.1e-13 50.1 12.7 5.7e-13 49.2 12.7 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srb 7TM_GPCR_Srab PF10292.9 CDJ82229.1 - 4.8e-12 45.4 10.1 4.8e-12 45.4 10.1 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Sra PF02117.16 CDJ82229.1 - 8.8e-10 37.9 19.1 1e-09 37.7 19.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sra 7TM_GPCR_Srab PF10292.9 CDJ82230.1 - 7e-16 58.0 16.8 2.5e-12 46.4 6.6 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Srb PF02175.16 CDJ82230.1 - 8.9e-14 51.8 21.2 8.9e-13 48.6 3.0 2.3 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srb 7TM_GPCR_Sra PF02117.16 CDJ82230.1 - 9.6e-08 31.2 7.6 9.6e-08 31.2 7.6 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Sra Sre PF03125.18 CDJ82230.1 - 9e-05 21.8 11.8 9e-05 21.8 11.8 2.4 1 1 1 2 2 2 1 C. elegans Sre G protein-coupled chemoreceptor Tetraspanin PF00335.20 CDJ82230.1 - 0.0025 17.5 2.0 0.0025 17.5 2.0 2.0 1 1 0 2 2 2 1 Tetraspanin family Neur_chan_memb PF02932.16 CDJ82230.1 - 0.0075 16.4 0.2 0.011 15.8 0.2 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region TMEM154 PF15102.6 CDJ82230.1 - 0.16 11.9 0.1 3.7 7.5 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family BatA PF07584.11 CDJ82230.1 - 1.7 9.1 6.9 4.5 7.7 0.1 3.2 4 0 0 4 4 4 0 Aerotolerance regulator N-terminal Col_cuticle_N PF01484.17 CDJ82231.1 - 1.1e-18 67.0 0.1 1.5e-18 66.6 0.1 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ82231.1 - 1.2e-18 66.6 117.0 7e-07 28.9 39.1 3.6 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) COX14 PF14880.6 CDJ82231.1 - 0.0013 18.5 0.6 0.0019 18.0 0.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c assembly NYN PF01936.18 CDJ82233.1 - 0.0018 18.8 0.0 0.0023 18.4 0.0 1.1 1 0 0 1 1 1 1 NYN domain SYF2 PF08231.12 CDJ82234.1 - 0.0013 19.2 0.9 0.0015 19.0 0.2 1.4 2 0 0 2 2 2 1 SYF2 splicing factor Auts2 PF15336.6 CDJ82234.1 - 0.0056 16.8 0.1 0.0056 16.8 0.1 1.8 1 1 0 1 1 1 1 Autism susceptibility gene 2 protein Rx_N PF18052.1 CDJ82234.1 - 0.016 15.4 1.0 0.029 14.6 1.0 1.3 1 0 0 1 1 1 0 Rx N-terminal domain IL17 PF06083.11 CDJ82235.1 - 0.0098 16.3 0.3 0.021 15.3 0.3 1.6 1 0 0 1 1 1 1 Interleukin-17 Spaetzle PF16077.5 CDJ82235.1 - 0.36 11.4 3.2 0.84 10.2 3.2 1.7 1 0 0 1 1 1 0 Spaetzle Cys_knot PF00007.22 CDJ82236.1 - 0.00029 21.1 0.9 0.00052 20.3 0.9 1.4 1 0 0 1 1 1 1 Cystine-knot domain E2_bind PF08825.10 CDJ82238.1 - 0.0031 17.6 1.8 0.017 15.2 0.1 2.3 2 0 0 2 2 2 1 E2 binding domain DUF3498 PF12004.8 CDJ82238.1 - 0.0066 15.7 3.4 0.0086 15.3 3.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3498) SHE3 PF17078.5 CDJ82238.1 - 0.029 14.1 2.1 0.029 14.1 2.1 1.6 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 LIAS_N PF16881.5 CDJ82239.1 - 1.6e-22 79.9 0.8 2.7e-22 79.2 0.2 1.6 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 CDJ82239.1 - 1.8e-08 34.9 0.1 3.2e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily ORC5_C PF14630.6 CDJ82240.1 - 8e-33 114.2 0.1 2.4e-32 112.6 0.1 1.7 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus DUF496 PF04363.12 CDJ82240.1 - 0.058 13.4 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF496) ACOX PF01756.19 CDJ82242.1 - 4.4e-39 133.9 0.0 8.9e-39 132.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 CDJ82242.1 - 1.2e-10 41.4 0.0 2.1e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 CDJ82242.1 - 0.0028 18.2 0.1 0.0063 17.1 0.1 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 CDJ82242.1 - 0.0057 16.9 0.1 0.018 15.3 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain MIT_LIKE_ACTX PF17556.2 CDJ82242.1 - 0.092 13.3 0.1 0.36 11.4 0.1 1.9 2 0 0 2 2 2 0 MIT-like atracotoxin family RabGAP-TBC PF00566.18 CDJ82243.1 - 2.2e-25 89.6 0.0 3.6e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Utp21 PF04192.12 CDJ82244.1 - 1.4e-51 175.3 3.3 2.3e-51 174.5 3.3 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 CDJ82244.1 - 3.9e-17 62.3 1.1 2.7e-06 28.0 0.1 7.3 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ82244.1 - 3.6e-16 59.2 0.3 0.024 14.9 0.0 7.0 3 3 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 CDJ82244.1 - 0.0019 18.5 0.1 0.005 17.1 0.1 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 CDJ82244.1 - 0.0037 16.3 0.2 0.067 12.1 0.0 2.5 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 CDJ82244.1 - 0.0045 16.0 0.3 0.08 11.8 0.0 2.8 2 1 1 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 CDJ82244.1 - 0.054 12.1 3.5 0.058 12.0 0.0 2.6 4 0 0 4 4 4 0 Nucleoporin Nup120/160 VID27 PF08553.10 CDJ82244.1 - 0.11 11.5 0.0 0.26 10.3 0.0 1.5 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain SNARE PF05739.19 CDJ82245.1 - 3.6e-09 36.5 1.6 5.6e-09 35.9 1.6 1.3 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 CDJ82245.1 - 0.0063 16.3 1.0 0.0076 16.0 1.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Nup88 PF10168.9 CDJ82245.1 - 0.0091 13.9 1.1 0.01 13.7 1.1 1.0 1 0 0 1 1 1 1 Nuclear pore component DUF16 PF01519.16 CDJ82245.1 - 0.015 15.8 1.0 0.02 15.4 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 Vip3A_N PF12495.8 CDJ82245.1 - 0.018 15.0 0.3 0.022 14.7 0.3 1.1 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal Transcrip_act PF04949.13 CDJ82245.1 - 0.019 14.8 0.9 0.022 14.6 0.9 1.1 1 0 0 1 1 1 0 Transcriptional activator KCH PF16944.5 CDJ82245.1 - 0.042 13.6 0.3 0.082 12.7 0.2 1.5 2 0 0 2 2 2 0 Fungal potassium channel XhlA PF10779.9 CDJ82245.1 - 0.068 13.4 1.6 0.086 13.1 0.3 1.8 2 0 0 2 2 2 0 Haemolysin XhlA Pex24p PF06398.11 CDJ82245.1 - 0.11 11.5 0.1 0.098 11.6 0.1 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin 7TM_GPCR_Srv PF10323.9 CDJ82246.1 - 6.8e-15 55.2 9.9 7.9e-15 55.0 9.9 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Srg PF02118.21 CDJ82246.1 - 0.0002 21.1 9.7 0.00026 20.8 9.7 1.0 1 0 0 1 1 1 1 Srg family chemoreceptor MtrE PF04206.12 CDJ82246.1 - 0.32 10.3 4.2 0.39 10.0 4.2 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit E RVT_1 PF00078.27 CDJ82247.1 - 0.0011 18.5 0.0 0.0028 17.2 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HemeBinding_Shp PF11545.8 CDJ82247.1 - 0.047 13.7 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 Cell surface heme-binding protein Shp Cystatin PF00031.21 CDJ82248.1 - 1.2e-08 35.1 0.0 1.5e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 CDJ82248.1 - 0.14 12.5 0.0 1.9 8.9 0.0 2.1 2 0 0 2 2 2 0 Aspartic acid proteinase inhibitor SCVP PF17619.2 CDJ82249.1 - 3.2e-12 47.1 0.1 3.9e-12 46.9 0.1 1.1 1 0 0 1 1 1 1 Secreted clade V proteins SCVP PF17619.2 CDJ82250.1 - 8.8e-13 48.9 0.2 2.3e-12 47.6 0.0 1.8 2 0 0 2 2 2 1 Secreted clade V proteins Cystatin PF00031.21 CDJ82250.1 - 4.9e-08 33.1 0.2 1.1e-07 32.1 0.1 1.7 2 0 0 2 2 2 1 Cystatin domain SQAPI PF16845.5 CDJ82250.1 - 0.00036 20.8 0.2 0.043 14.2 0.1 2.5 1 1 1 2 2 2 2 Aspartic acid proteinase inhibitor WD40 PF00400.32 CDJ82251.1 - 1.7e-07 31.8 0.1 0.03 15.2 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ82251.1 - 7.1e-06 26.2 0.0 0.071 13.4 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ82251.1 - 0.049 12.6 1.8 1.3 7.9 0.0 3.0 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Glutaredoxin PF00462.24 CDJ82254.1 - 7.6e-17 61.3 0.1 1.2e-16 60.7 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 CDJ82254.1 - 0.0012 19.3 0.0 0.0019 18.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain GST_N_3 PF13417.6 CDJ82254.1 - 0.0053 17.2 0.0 0.0073 16.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MutS_II PF05188.17 CDJ82254.1 - 0.071 13.4 0.1 0.097 12.9 0.1 1.2 1 0 0 1 1 1 0 MutS domain II DSBA PF01323.20 CDJ82254.1 - 0.089 12.6 0.1 1 9.1 0.0 2.2 1 1 1 2 2 2 0 DSBA-like thioredoxin domain PRCC PF10253.9 CDJ82254.1 - 0.18 12.6 0.2 0.2 12.4 0.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting S-AdoMet_synt_C PF02773.16 CDJ82256.1 - 7.1e-68 226.9 0.0 1.9e-67 225.5 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 CDJ82256.1 - 4e-45 152.9 0.0 7.9e-45 152.0 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 CDJ82256.1 - 6.9e-44 148.6 0.3 1.5e-43 147.5 0.3 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 CDJ82256.1 - 0.15 10.8 0.7 1.4 7.6 0.2 2.0 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) MBOAT PF03062.19 CDJ82257.1 - 4.7e-53 180.8 9.1 4.7e-53 180.8 9.1 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family RT_RNaseH PF17917.1 CDJ82258.1 - 1.9e-32 111.7 0.0 7.4e-32 109.8 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ82258.1 - 1.2e-29 102.3 0.0 3.6e-29 100.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ82258.1 - 2e-22 79.6 0.0 6.5e-22 78.0 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ82258.1 - 1.1e-17 63.8 0.2 2.1e-17 63.0 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 CDJ82258.1 - 4.1e-09 36.3 0.0 8.7e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 CDJ82258.1 - 2.5e-05 24.0 0.1 6.8e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 CDJ82258.1 - 0.0052 17.0 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger ABC_membrane PF00664.23 CDJ82259.1 - 3.2e-55 187.7 12.5 3.2e-55 187.7 12.5 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ82259.1 - 2.1e-32 112.5 0.0 4.9e-32 111.3 0.0 1.6 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 CDJ82259.1 - 9.3e-08 31.8 1.4 3.9e-06 26.5 1.4 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDJ82259.1 - 0.021 15.2 0.1 0.12 12.7 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 CDJ82259.1 - 0.034 14.4 0.1 0.17 12.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 CDJ82259.1 - 0.041 14.1 0.8 0.68 10.2 0.8 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 CDJ82259.1 - 0.057 13.1 0.1 0.17 11.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CDJ82259.1 - 0.067 13.1 0.0 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase DAGK_prokar PF01219.19 CDJ82259.1 - 0.095 12.5 4.6 3.8 7.4 0.6 2.7 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase AAA_29 PF13555.6 CDJ82259.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 CDJ82259.1 - 0.15 12.5 0.2 2.5 8.5 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.25 CDJ82260.1 - 2.8e-75 253.1 0.0 3.3e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ82260.1 - 7e-47 159.9 0.0 8.7e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ82260.1 - 9.3e-07 28.4 0.0 1.4e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CDJ82260.1 - 0.0017 17.3 0.0 0.0026 16.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 CDJ82260.1 - 0.032 13.8 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.11 CDJ82260.1 - 0.072 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PIP49_C PF12260.8 CDJ82260.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.5 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 RIO1 PF01163.22 CDJ82260.1 - 0.12 12.0 0.0 0.29 10.7 0.0 1.6 1 1 1 2 2 2 0 RIO1 family ESF1 PF18209.1 CDJ82261.1 - 2.4 8.1 10.4 8.6 6.4 2.1 2.9 2 0 0 2 2 2 0 Embryo surrounding factor 1 FHIPEP PF00771.20 CDJ82262.1 - 0.23 9.9 0.1 0.3 9.5 0.1 1.1 1 0 0 1 1 1 0 FHIPEP family ACCA PF03255.14 CDJ82262.1 - 0.25 11.2 1.5 6.6 6.6 0.2 2.2 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TRAPP PF04051.16 CDJ82264.1 - 1.6e-35 121.9 0.0 1.9e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DNApol_Exo PF18136.1 CDJ82265.1 - 1.2e-70 237.8 0.0 1.2e-70 237.8 0.0 2.2 2 0 0 2 2 2 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 CDJ82265.1 - 2.6e-40 138.7 0.0 1.9e-39 135.8 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase family A PDZ_6 PF17820.1 CDJ82265.1 - 0.063 13.1 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 PDZ domain AF-4 PF05110.13 CDJ82265.1 - 0.19 9.8 28.4 0.3 9.1 28.4 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF3395 PF11875.8 CDJ82266.1 - 1.8e-34 118.9 0.0 3.5e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 CDJ82266.1 - 3e-21 75.3 3.4 7.8e-21 74.0 2.5 2.0 2 0 0 2 2 2 1 DnaJ domain DUF2367 PF10164.9 CDJ82267.1 - 1.3e-06 28.8 13.1 1.3e-06 28.8 13.1 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) zf-LITAF-like PF10601.9 CDJ82267.1 - 1.3 9.3 16.6 2.3 8.5 16.6 1.4 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Lig_C PF18330.1 CDJ82269.1 - 0.0013 18.8 0.0 0.027 14.5 0.0 2.2 2 0 0 2 2 2 1 Ligase Pab1020 C-terminal region Baculo_LEF-11 PF06385.12 CDJ82269.1 - 0.029 14.9 0.1 9.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Baculovirus LEF-11 protein Tox-MPTase3 PF15639.6 CDJ82269.1 - 0.068 13.0 0.0 7.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Metallopeptidase toxin 3 Bcl-2 PF00452.19 CDJ82269.1 - 0.1 13.3 0.0 25 5.6 0.0 2.8 2 2 0 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family SapB_2 PF03489.17 CDJ82269.1 - 0.14 12.3 2.7 8.8 6.5 0.2 2.9 3 0 0 3 3 3 0 Saposin-like type B, region 2 PEPCK_GTP PF00821.18 CDJ82270.1 - 1.5e-94 316.8 0.2 1.9e-94 316.4 0.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 CDJ82270.1 - 1.7e-63 214.2 0.0 2.3e-63 213.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain 7tm_1 PF00001.21 CDJ82271.1 - 1.4e-14 54.1 15.0 1.9e-14 53.7 15.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) AMP-binding PF00501.28 CDJ82272.1 - 5.7e-100 334.9 0.0 9.2e-100 334.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ82272.1 - 0.00031 21.6 0.2 0.001 20.0 0.2 2.0 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 CDJ82273.1 - 8.5e-33 113.7 46.4 3.8e-31 108.3 32.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CDJ82273.1 - 2.8e-06 26.9 0.4 2.8e-06 26.9 0.4 3.5 2 1 2 4 4 4 2 Uncharacterised MFS-type transporter YbfB Holin_9 PF16936.5 CDJ82273.1 - 0.012 15.7 1.9 0.012 15.7 1.9 2.5 2 0 0 2 2 2 0 Putative holin DUF2834 PF11196.8 CDJ82273.1 - 0.02 15.2 0.8 0.18 12.2 0.5 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2834) E1_DerP2_DerF2 PF02221.15 CDJ82274.1 - 0.019 15.4 0.1 0.031 14.7 0.1 1.5 1 1 0 1 1 1 0 ML domain tRNA-synt_1g PF09334.11 CDJ82275.1 - 3.6e-72 243.3 1.7 4.1e-70 236.5 1.7 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CDJ82275.1 - 8.4e-08 30.9 0.7 1.6e-07 30.0 0.2 1.7 1 1 1 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDJ82275.1 - 4.2e-05 23.5 0.0 0.00023 21.1 0.0 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CDJ82275.1 - 0.0001 21.8 0.0 0.00027 20.4 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 CDJ82275.1 - 0.046 12.6 0.0 0.085 11.8 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (K) CS PF04969.16 CDJ82276.1 - 1.1e-11 45.5 0.1 3.1e-11 44.1 0.1 1.8 2 0 0 2 2 2 1 CS domain Siah-Interact_N PF09032.11 CDJ82276.1 - 1.6e-05 25.1 0.2 1.6e-05 25.1 0.2 2.1 2 0 0 2 2 2 1 Siah interacting protein, N terminal SGS PF05002.15 CDJ82276.1 - 1 9.5 10.0 0.026 14.6 3.3 1.9 2 0 0 2 2 2 0 SGS domain Ras PF00071.22 CDJ82277.1 - 2.5e-58 196.3 0.2 2.9e-58 196.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ82277.1 - 1.6e-21 76.7 0.0 2.7e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ82277.1 - 6.2e-10 38.8 0.0 7e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CDJ82277.1 - 2e-05 24.5 0.1 0.055 13.4 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CDJ82277.1 - 3.2e-05 23.6 0.5 0.00013 21.5 0.2 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDJ82277.1 - 0.00022 21.3 0.1 0.00032 20.8 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 CDJ82277.1 - 0.02 14.1 0.2 1.3 8.1 0.0 2.2 1 1 0 2 2 2 0 G-protein alpha subunit Peptidase_C65 PF10275.9 CDJ82278.1 - 3.9e-64 216.5 0.0 6.9e-64 215.7 0.0 1.4 1 1 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 CDJ82278.1 - 0.0032 17.9 0.0 0.61 10.6 0.0 2.4 2 0 0 2 2 2 2 OTU-like cysteine protease RsgA_N PF16745.5 CDJ82278.1 - 0.078 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 RsgA N-terminal domain GDA1_CD39 PF01150.17 CDJ82279.1 - 3.5e-70 236.8 0.0 1.1e-69 235.2 0.0 1.7 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family RuvX PF03652.15 CDJ82280.1 - 0.13 12.6 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Holliday junction resolvase Peptidase_M14 PF00246.24 CDJ82282.1 - 2.2e-73 247.6 0.0 2.7e-73 247.3 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 CDJ82282.1 - 1.1e-10 41.7 2.3 2.7e-09 37.3 0.4 3.1 3 0 0 3 3 3 1 Carboxypeptidase activation peptide Biliv-reduc_cat PF09166.10 CDJ82283.1 - 0.17 12.2 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 Biliverdin reductase, catalytic Sarcolipin PF05366.11 CDJ82284.1 - 0.0056 16.4 0.4 0.0082 15.8 0.4 1.2 1 0 0 1 1 1 1 Sarcolipin PDZ PF00595.24 CDJ82285.1 - 1.6e-16 60.4 0.7 3.4e-16 59.4 0.3 1.7 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 CDJ82285.1 - 3.7e-08 33.1 0.1 7.4e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ82285.1 - 0.0001 22.5 0.1 0.0002 21.6 0.1 1.5 1 0 0 1 1 1 1 PDZ domain RRP7 PF12923.7 CDJ82286.1 - 0.055 13.6 0.2 0.08 13.1 0.2 1.1 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Ig_6 PF18452.1 CDJ82287.1 - 0.081 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain zf-C2H2_4 PF13894.6 CDJ82287.1 - 1.7 9.7 8.4 0.74 10.8 0.8 3.3 4 0 0 4 4 4 0 C2H2-type zinc finger ASC PF00858.24 CDJ82288.1 - 3.9e-20 72.3 13.9 8.5e-20 71.1 13.9 1.5 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel Vps54 PF07928.12 CDJ82289.1 - 9.1e-44 149.1 1.1 5.4e-43 146.6 0.3 2.7 3 0 0 3 3 3 1 Vps54-like protein Vps54_N PF10475.9 CDJ82289.1 - 5e-14 52.3 2.2 8.3e-14 51.5 0.5 2.1 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Sec8_exocyst PF04048.14 CDJ82289.1 - 0.0063 16.4 3.5 0.0072 16.2 0.2 2.8 3 1 0 3 3 3 1 Sec8 exocyst complex component specific domain Ins_allergen_rp PF06757.13 CDJ82289.1 - 0.11 12.5 1.4 2.3 8.1 0.0 2.6 3 0 0 3 3 3 0 Insect allergen related repeat, nitrile-specifier detoxification Aft1_HRA PF11786.8 CDJ82289.1 - 0.14 12.5 0.1 0.36 11.2 0.1 1.7 1 0 0 1 1 1 0 Aft1 HRA domain MFS_1 PF07690.16 CDJ82290.1 - 2.2e-39 135.4 27.9 9.8e-30 103.7 9.7 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily CbtA PF09490.10 CDJ82290.1 - 0.11 12.2 3.8 0.33 10.7 3.8 1.9 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) SET PF00856.28 CDJ82291.1 - 3e-09 37.5 1.8 4.5e-08 33.7 1.8 2.5 1 1 0 1 1 1 1 SET domain PHD PF00628.29 CDJ82291.1 - 0.018 14.9 39.7 0.023 14.6 1.2 4.4 4 0 0 4 4 4 0 PHD-finger Spin-Ssty PF02513.17 CDJ82291.1 - 0.057 13.2 0.5 0.42 10.4 0.1 2.3 2 0 0 2 2 2 0 Spin/Ssty Family C1_1 PF00130.22 CDJ82291.1 - 0.097 12.6 28.1 0.66 9.9 8.4 3.9 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 CDJ82291.1 - 3.5 7.3 11.0 16 5.1 0.0 3.7 3 0 0 3 3 3 0 PHD-finger p450 PF00067.22 CDJ82292.1 - 1.4e-92 310.9 0.4 1.8e-92 310.5 0.4 1.1 1 0 0 1 1 1 1 Cytochrome P450 TH1 PF04858.13 CDJ82293.1 - 1.1e-55 189.4 0.0 1.2e-55 189.2 0.0 1.0 1 0 0 1 1 1 1 TH1 protein Glyco_hydro_71 PF03659.14 CDJ82295.1 - 0.007 15.2 0.1 0.008 15.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 p25-alpha PF05517.12 CDJ82295.1 - 0.034 14.3 0.5 0.044 13.9 0.5 1.1 1 0 0 1 1 1 0 p25-alpha Peptidase_M14 PF00246.24 CDJ82296.1 - 3.1e-84 283.2 0.2 4.5e-84 282.7 0.2 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 CDJ82296.1 - 4.1e-10 39.9 0.1 8.8e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide ShK PF01549.24 CDJ82296.1 - 2.8e-06 27.7 8.8 6.4e-06 26.6 8.8 1.6 1 0 0 1 1 1 1 ShK domain-like Pkinase PF00069.25 CDJ82297.1 - 9.3e-60 202.2 0.0 6.6e-59 199.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ82297.1 - 1.6e-31 109.6 0.0 8.3e-31 107.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ82297.1 - 1e-05 24.6 0.0 1.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDJ82297.1 - 0.0003 20.2 0.0 0.00052 19.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CDJ82297.1 - 0.0042 17.0 0.0 0.16 11.9 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family LPD24 PF18839.1 CDJ82297.1 - 0.015 15.5 0.5 0.25 11.6 0.4 2.8 2 1 0 2 2 2 0 Large polyvalent protein associated domain 24 F-box_4 PF15966.5 CDJ82298.1 - 0.13 12.2 0.2 0.23 11.4 0.2 1.4 1 0 0 1 1 1 0 F-box DUF148 PF02520.17 CDJ82299.1 - 1.4e-25 89.6 6.6 1.6e-25 89.3 6.6 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 MAP65_ASE1 PF03999.12 CDJ82299.1 - 0.0035 16.1 2.3 0.0043 15.8 2.3 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DUF948 PF06103.11 CDJ82299.1 - 0.0082 16.4 0.5 0.012 15.8 0.4 1.3 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) YkyA PF10368.9 CDJ82299.1 - 0.0089 15.7 4.6 0.017 14.8 4.6 1.4 1 1 0 1 1 1 1 Putative cell-wall binding lipoprotein Baculo_PEP_C PF04513.12 CDJ82299.1 - 0.015 15.4 0.0 0.02 14.9 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus RmuC PF02646.16 CDJ82299.1 - 0.016 14.4 1.5 0.022 13.9 1.5 1.2 1 0 0 1 1 1 0 RmuC family Erp_C PF06780.11 CDJ82299.1 - 0.026 14.5 0.1 0.034 14.2 0.1 1.2 1 0 0 1 1 1 0 Erp protein C-terminus DUF3437 PF11919.8 CDJ82299.1 - 0.034 14.0 1.7 0.22 11.4 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3437) IFT57 PF10498.9 CDJ82299.1 - 0.049 12.6 4.4 0.06 12.3 4.4 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF1664 PF07889.12 CDJ82299.1 - 0.057 13.5 1.3 0.082 12.9 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DHC PF09626.10 CDJ82299.1 - 0.063 14.2 1.3 0.086 13.7 1.3 1.2 1 0 0 1 1 1 0 Dihaem cytochrome c PHTB1_C PF14728.6 CDJ82299.1 - 0.088 11.9 3.1 0.11 11.6 3.1 1.1 1 0 0 1 1 1 0 PTHB1 C-terminus OmpH PF03938.14 CDJ82299.1 - 0.11 12.8 2.3 0.13 12.6 1.9 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Muted PF14942.6 CDJ82299.1 - 0.15 12.4 4.6 0.26 11.6 4.6 1.5 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF4422 PF14393.6 CDJ82299.1 - 0.21 11.4 5.2 0.29 10.9 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4422) PIF PF05092.12 CDJ82299.1 - 0.25 10.0 0.3 0.3 9.8 0.3 1.1 1 0 0 1 1 1 0 Per os infectivity Fib_alpha PF08702.10 CDJ82299.1 - 0.33 11.1 2.1 0.43 10.8 2.1 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1043 PF06295.12 CDJ82299.1 - 0.65 10.0 7.5 2.4 8.2 7.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) TACC_C PF05010.14 CDJ82299.1 - 1.4 8.7 8.1 4.2 7.1 8.1 1.6 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Mito_carr PF00153.27 CDJ82301.1 - 7.8e-23 80.2 0.0 1e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein EF-hand_7 PF13499.6 CDJ82302.1 - 1.2e-16 60.9 2.9 2.3e-10 40.8 0.7 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ82302.1 - 1.6e-13 49.4 0.5 0.0016 18.2 0.0 3.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 CDJ82302.1 - 2.1e-13 48.8 4.7 0.00018 20.9 0.2 4.2 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 CDJ82302.1 - 3.2e-07 29.5 5.8 0.0017 17.7 0.5 3.5 3 0 0 3 3 3 2 EF hand EF-hand_10 PF14788.6 CDJ82302.1 - 5.4e-07 29.4 0.1 0.045 13.6 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDJ82302.1 - 9.6e-05 22.2 2.9 2.2 8.2 0.7 3.6 2 1 1 3 3 3 2 EF-hand domain pair HeLo PF14479.6 CDJ82302.1 - 0.0087 15.9 0.1 0.011 15.6 0.1 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation EF-hand_9 PF14658.6 CDJ82302.1 - 0.011 16.1 0.0 5.4 7.4 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain SPARC_Ca_bdg PF10591.9 CDJ82302.1 - 0.012 15.9 0.4 0.35 11.2 0.1 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Slx4 PF09494.10 CDJ82302.1 - 0.099 12.6 0.1 1.4 8.9 0.0 2.6 3 0 0 3 3 3 0 Slx4 endonuclease EF-hand_4 PF12763.7 CDJ82302.1 - 0.1 12.6 2.8 3.1 7.8 0.0 2.7 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand LIM PF00412.22 CDJ82303.1 - 1.8e-11 44.1 16.0 2.1e-06 27.8 5.6 2.1 2 0 0 2 2 2 2 LIM domain ARGLU PF15346.6 CDJ82304.1 - 2.6e-20 72.8 29.0 2.6e-20 72.8 29.0 2.1 2 0 0 2 2 2 1 Arginine and glutamate-rich 1 zf-C3HC4_3 PF13920.6 CDJ82305.1 - 4.2e-08 32.9 11.8 4.2e-08 32.9 11.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) CTU2 PF10288.9 CDJ82305.1 - 3 8.1 11.3 51 4.2 10.8 2.4 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Ribosomal_S11 PF00411.19 CDJ82307.1 - 3.5e-47 159.3 1.3 4.4e-47 159.0 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 CDJ82307.1 - 0.021 15.1 0.0 0.044 14.0 0.0 1.5 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) EI24 PF07264.11 CDJ82308.1 - 3.7e-09 37.1 13.4 5.8e-09 36.4 13.4 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Ribosomal_L36e PF01158.18 CDJ82309.1 - 1.9e-42 143.4 6.1 2.1e-42 143.2 6.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e PP-binding PF00550.25 CDJ82310.1 - 7.8e-10 39.0 0.0 1.1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site 7TM_GPCR_Srd PF10317.9 CDJ82311.1 - 5.7e-10 38.9 1.0 6.6e-10 38.7 1.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd Peptidase_C48 PF02902.19 CDJ82312.1 - 0.0011 18.8 0.0 0.0015 18.4 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain BET PF17035.5 CDJ82314.1 - 7e-05 22.9 0.3 0.00044 20.4 0.1 2.3 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.25 CDJ82314.1 - 0.00081 19.4 0.1 0.0019 18.2 0.1 1.6 1 0 0 1 1 1 1 Bromodomain PRD PF00874.20 CDJ82315.1 - 0.063 13.6 0.0 0.19 12.1 0.0 1.8 1 1 1 2 2 2 0 PRD domain MRI PF15325.6 CDJ82315.1 - 0.092 13.8 0.1 0.16 13.0 0.1 1.5 1 0 0 1 1 1 0 Modulator of retrovirus infection Patatin PF01734.22 CDJ82316.1 - 8.2e-16 58.8 0.0 2.1e-15 57.4 0.0 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase LSM PF01423.22 CDJ82317.1 - 3.2e-12 46.0 0.0 3.7e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain ANF_receptor PF01094.28 CDJ82320.1 - 3.7e-35 121.7 0.7 5.7e-35 121.1 0.7 1.3 1 1 0 1 1 1 1 Receptor family ligand binding region PAE PF03283.13 CDJ82320.1 - 0.026 13.6 0.1 0.036 13.2 0.1 1.2 1 0 0 1 1 1 0 Pectinacetylesterase CMAS PF02353.20 CDJ82321.1 - 6.8e-77 258.4 0.0 8.5e-77 258.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 CDJ82321.1 - 1.3e-10 41.8 0.0 2.4e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ82321.1 - 3e-08 33.7 0.0 4.8e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ82321.1 - 5e-08 32.9 0.0 8.4e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ82321.1 - 7.7e-08 32.9 0.0 1.4e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ82321.1 - 2.6e-07 31.3 0.0 5.3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ82321.1 - 0.00046 19.8 0.0 0.00081 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain ADH_zinc_N PF00107.26 CDJ82321.1 - 0.0063 16.5 0.0 0.011 15.7 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase PCMT PF01135.19 CDJ82321.1 - 0.016 15.0 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 CDJ82321.1 - 0.052 12.5 0.0 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PrmA PF06325.13 CDJ82321.1 - 0.095 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ldh_2 PF02615.14 CDJ82322.1 - 1.8e-107 359.4 0.1 2.2e-107 359.1 0.1 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase CRM1_repeat_2 PF18784.1 CDJ82322.1 - 0.027 14.1 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 Ldh_2 PF02615.14 CDJ82323.1 - 2.5e-107 358.9 0.1 3e-107 358.7 0.1 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase ERCC4 PF02732.15 CDJ82324.1 - 3.3e-18 66.4 0.0 5.4e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain NAD_binding_5 PF07994.12 CDJ82325.1 - 3.9e-132 440.5 0.0 5.1e-132 440.1 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 CDJ82325.1 - 4.1e-47 159.0 0.1 8.9e-47 157.9 0.1 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Kelch_1 PF01344.25 CDJ82327.1 - 1.9e-54 181.0 11.6 1.2e-12 47.1 0.0 6.4 6 0 0 6 6 6 6 Kelch motif BACK PF07707.15 CDJ82327.1 - 4.5e-30 103.8 0.3 8.5e-30 102.9 0.3 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 CDJ82327.1 - 3e-24 85.4 0.0 8.7e-24 83.9 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.6 CDJ82327.1 - 5.8e-18 64.5 2.5 2e-05 24.7 0.0 6.2 3 1 3 6 6 6 5 Kelch motif Kelch_3 PF13415.6 CDJ82327.1 - 1.5e-09 37.9 3.3 0.04 14.2 0.0 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 CDJ82327.1 - 2.7e-09 36.6 4.6 0.11 12.5 0.0 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 CDJ82327.1 - 9.9e-08 31.9 9.0 0.0079 16.2 0.1 5.7 5 1 1 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ82327.1 - 0.00084 19.3 2.7 0.97 9.5 0.1 4.5 4 0 0 4 4 4 1 Kelch motif PQQ_3 PF13570.6 CDJ82327.1 - 0.28 11.8 10.3 11 6.6 0.0 4.9 5 0 0 5 5 5 0 PQQ-like domain Pkinase PF00069.25 CDJ82328.1 - 2.5e-67 227.1 0.0 3.1e-67 226.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ82328.1 - 3.2e-37 128.2 0.0 4.4e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ82328.1 - 6.6e-06 25.2 0.0 1.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDJ82328.1 - 0.00039 19.8 0.0 0.0013 18.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CDJ82328.1 - 0.00048 20.1 0.0 0.037 14.0 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family POLO_box PF00659.18 CDJ82328.1 - 0.0007 19.7 0.0 0.43 10.8 0.0 2.5 2 0 0 2 2 2 2 POLO box duplicated region p450 PF00067.22 CDJ82330.1 - 2.5e-110 369.4 0.0 4e-110 368.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 VWA PF00092.28 CDJ82331.1 - 8.8e-18 65.2 0.6 8.8e-18 65.2 0.6 3.6 4 0 0 4 4 4 2 von Willebrand factor type A domain VWA_2 PF13519.6 CDJ82331.1 - 4.5e-13 49.8 3.1 7.1e-10 39.5 0.1 3.9 3 0 0 3 3 3 2 von Willebrand factor type A domain Qn_am_d_aIII PF09099.10 CDJ82331.1 - 0.12 12.8 0.1 0.34 11.3 0.1 1.7 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III Rubella_E2 PF05749.11 CDJ82331.1 - 1.4 8.4 8.1 1.1 8.6 0.6 2.7 3 0 0 3 3 3 0 Rubella membrane glycoprotein E2 Lyase_aromatic PF00221.19 CDJ82332.1 - 3.9e-186 619.3 0.4 4.6e-186 619.0 0.4 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Par3_HAL_N_term PF12053.8 CDJ82332.1 - 0.03 14.5 0.1 0.11 12.8 0.1 2.0 1 0 0 1 1 1 0 N-terminal of Par3 and HAL proteins Alpha-E PF04168.12 CDJ82332.1 - 0.095 12.5 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. IBB PF01749.20 CDJ82333.1 - 0.0071 16.8 0.4 0.02 15.3 0.4 1.7 1 0 0 1 1 1 1 Importin beta binding domain Mis14 PF08641.12 CDJ82333.1 - 0.28 11.5 1.1 0.71 10.2 0.7 1.9 2 0 0 2 2 2 0 Kinetochore protein Mis14 like AAA PF00004.29 CDJ82334.1 - 3.3e-95 315.5 0.0 2.9e-46 157.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ82334.1 - 8.6e-26 89.5 3.9 1.1e-13 50.7 0.6 3.1 3 0 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 CDJ82334.1 - 5.9e-21 74.5 1.7 1.3e-20 73.3 1.2 1.9 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 CDJ82334.1 - 5.8e-14 52.1 0.0 1e-05 25.3 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDJ82334.1 - 1.3e-12 48.5 0.8 0.00043 20.7 0.0 4.4 3 2 0 3 3 2 2 AAA ATPase domain AAA_5 PF07728.14 CDJ82334.1 - 2.2e-11 43.9 0.1 2.9e-05 24.1 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.17 CDJ82334.1 - 7.5e-11 41.6 0.0 3.2e-10 39.6 0.0 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.6 CDJ82334.1 - 1.7e-10 41.2 0.0 9.6e-05 22.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 CDJ82334.1 - 3.9e-10 40.1 0.0 6.1e-05 23.2 0.0 3.0 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDJ82334.1 - 2.8e-09 37.3 0.2 0.018 15.3 0.1 4.2 2 2 1 3 3 2 2 AAA domain TIP49 PF06068.13 CDJ82334.1 - 1.8e-08 34.0 0.0 0.0019 17.5 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 CDJ82334.1 - 9.7e-08 32.6 0.0 0.016 15.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 CDJ82334.1 - 1.7e-07 31.2 0.0 0.028 14.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Vps4_C PF09336.10 CDJ82334.1 - 3.6e-07 30.1 0.2 1.2e-05 25.2 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.21 CDJ82334.1 - 4.8e-07 29.4 0.1 0.023 14.1 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CDJ82334.1 - 5.3e-07 29.7 0.0 0.048 13.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CDJ82334.1 - 1.2e-06 28.8 0.0 0.0082 16.5 0.0 2.7 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.27 CDJ82334.1 - 2.8e-06 27.9 0.1 0.0074 16.8 0.0 3.6 3 1 0 3 3 2 1 ABC transporter AAA_28 PF13521.6 CDJ82334.1 - 4.9e-06 26.9 0.2 0.24 11.6 0.0 3.4 3 1 1 4 4 3 2 AAA domain Parvo_NS1 PF01057.17 CDJ82334.1 - 5.5e-06 25.7 0.0 0.018 14.2 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 CDJ82334.1 - 1e-05 25.2 0.3 0.36 10.4 0.0 3.6 2 1 0 3 3 3 1 AAA domain ATPase PF06745.13 CDJ82334.1 - 1.1e-05 24.9 0.1 1.4 8.2 0.0 3.5 3 0 0 3 3 3 2 KaiC Sigma54_activat PF00158.26 CDJ82334.1 - 1.4e-05 24.9 0.0 0.17 11.6 0.0 3.4 2 1 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 CDJ82334.1 - 1.5e-05 25.2 0.0 0.17 12.0 0.0 3.6 3 0 0 3 3 3 2 Sigma-54 interaction domain Bac_DnaA PF00308.18 CDJ82334.1 - 2.7e-05 24.1 0.0 0.095 12.5 0.0 2.7 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_7 PF12775.7 CDJ82334.1 - 3.3e-05 23.5 0.0 0.2 11.2 0.0 2.8 2 0 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 CDJ82334.1 - 3.8e-05 23.7 0.2 0.15 11.9 0.0 3.5 3 1 0 3 3 3 1 NACHT domain TsaE PF02367.17 CDJ82334.1 - 0.00015 21.7 0.0 0.3 11.1 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 CDJ82334.1 - 0.00015 21.5 0.0 0.011 15.5 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 CDJ82334.1 - 0.0002 21.2 0.0 0.47 10.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 CDJ82334.1 - 0.0002 21.3 0.1 0.56 10.1 0.0 3.6 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea PhoH PF02562.16 CDJ82334.1 - 0.00036 20.0 0.1 0.89 9.0 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein Zeta_toxin PF06414.12 CDJ82334.1 - 0.00091 18.6 0.0 0.94 8.7 0.0 2.8 3 0 0 3 3 2 1 Zeta toxin AAA_3 PF07726.11 CDJ82334.1 - 0.0012 18.7 0.0 2 8.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 CDJ82334.1 - 0.0014 17.8 0.0 0.3 10.2 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain DUF815 PF05673.13 CDJ82334.1 - 0.0014 17.8 0.0 0.53 9.4 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) UFD1 PF03152.14 CDJ82334.1 - 0.0015 18.0 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 ResIII PF04851.15 CDJ82334.1 - 0.0019 18.2 0.0 0.27 11.2 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CDJ82334.1 - 0.0031 16.8 0.0 1.4 8.0 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 CDJ82334.1 - 0.0035 17.2 0.2 3.5 7.3 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CDJ82334.1 - 0.0039 17.6 5.2 0.89 10.0 0.0 3.6 5 0 0 5 5 2 2 AAA domain Rad17 PF03215.15 CDJ82334.1 - 0.0045 16.9 0.0 0.62 10.0 0.0 2.7 3 0 0 3 3 2 1 Rad17 P-loop domain AAA_19 PF13245.6 CDJ82334.1 - 0.0049 17.2 1.1 3.5 8.0 0.2 3.3 3 1 0 4 4 2 1 AAA domain AAA_30 PF13604.6 CDJ82334.1 - 0.034 13.9 0.1 4.2 7.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CDJ82334.1 - 0.037 13.9 0.7 9.2 6.1 0.0 3.7 3 1 1 4 4 3 0 NTPase Cytidylate_kin PF02224.18 CDJ82334.1 - 0.054 13.2 0.0 13 5.5 0.0 2.9 2 0 0 2 2 2 0 Cytidylate kinase SKI PF01202.22 CDJ82334.1 - 0.086 13.0 0.7 15 5.7 0.0 3.1 3 0 0 3 3 2 0 Shikimate kinase AAA_23 PF13476.6 CDJ82334.1 - 0.11 12.9 0.3 18 5.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain KAP_NTPase PF07693.14 CDJ82334.1 - 0.15 11.2 0.0 4.7 6.4 0.0 2.4 2 1 0 2 2 2 0 KAP family P-loop domain Lustrin_cystein PF14625.6 CDJ82335.1 - 0.00068 20.0 6.0 0.0014 19.0 6.0 1.6 1 0 0 1 1 1 1 Lustrin, cysteine-rich repeated domain Img2 PF05046.14 CDJ82335.1 - 0.1 12.9 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) 7tm_1 PF00001.21 CDJ82336.1 - 1.2e-11 44.5 20.3 1.6e-11 44.0 20.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Na_H_antiport_1 PF06965.12 CDJ82336.1 - 0.059 12.2 3.2 1.9 7.3 1.2 2.4 2 0 0 2 2 2 0 Na+/H+ antiporter 1 60KD_IMP PF02096.20 CDJ82336.1 - 0.064 13.1 0.4 0.064 13.1 0.4 2.0 2 1 0 2 2 2 0 60Kd inner membrane protein PsbM PF05151.12 CDJ82336.1 - 0.2 11.5 2.4 0.81 9.6 2.4 2.0 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) DUF3989 PF13150.6 CDJ82336.1 - 0.25 11.1 2.5 8.3 6.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3989) Collagen PF01391.18 CDJ82337.1 - 0.0011 18.7 13.9 0.011 15.5 13.9 2.4 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) DuoxA PF10204.9 CDJ82340.1 - 7.8e-74 248.2 14.2 4e-64 216.3 1.8 2.0 2 0 0 2 2 2 2 Dual oxidase maturation factor Doppel PF11466.8 CDJ82340.1 - 0.087 12.5 2.1 0.23 11.1 2.1 1.7 1 0 0 1 1 1 0 Prion-like protein Doppel NHL PF01436.21 CDJ82341.1 - 6.3e-44 145.8 20.3 1.7e-09 37.2 0.1 6.5 6 0 0 6 6 6 6 NHL repeat DUF5128 PF17170.4 CDJ82341.1 - 6.7e-21 74.8 5.7 5.1e-08 32.4 0.1 4.2 2 1 2 4 4 4 4 6-bladed beta-propeller SGL PF08450.12 CDJ82341.1 - 2.6e-10 40.3 0.1 1.5e-05 24.7 0.0 3.0 3 0 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region zf-C3HC4 PF00097.25 CDJ82341.1 - 1.2e-09 37.9 14.0 1.2e-09 37.9 14.0 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ82341.1 - 9.5e-09 35.1 13.4 9.5e-09 35.1 13.4 2.3 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDJ82341.1 - 2.4e-07 30.5 11.5 2.4e-07 30.5 11.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ82341.1 - 1.7e-06 27.8 15.0 1.7e-06 27.8 15.0 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ82341.1 - 1e-05 25.6 14.9 1e-05 25.6 14.9 2.5 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CDJ82341.1 - 5.6e-05 23.0 12.0 5.6e-05 23.0 12.0 2.6 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CDJ82341.1 - 5.6e-05 23.4 13.5 5.6e-05 23.4 13.5 2.8 2 0 0 2 2 2 1 Ring finger domain Phytase-like PF13449.6 CDJ82341.1 - 0.00016 21.7 0.0 17 5.2 0.0 4.9 4 1 1 5 5 5 0 Esterase-like activity of phytase DUF4934 PF16288.5 CDJ82341.1 - 0.00066 19.6 5.1 0.11 12.4 0.1 3.5 1 1 4 5 5 5 3 Domain of unknown function (DUF4934) SBBP PF06739.11 CDJ82341.1 - 0.0038 17.2 1.4 0.47 10.5 0.0 2.8 3 0 0 3 3 3 1 Beta-propeller repeat RIH_assoc PF08454.11 CDJ82341.1 - 0.014 15.2 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 RyR and IP3R Homology associated zf-RING_11 PF17123.5 CDJ82341.1 - 0.025 14.3 3.5 0.072 12.8 3.5 1.9 1 0 0 1 1 1 0 RING-like zinc finger Lactonase PF10282.9 CDJ82341.1 - 0.026 13.8 0.3 0.71 9.1 0.1 2.4 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller SRP9-21 PF05486.12 CDJ82342.1 - 7.1e-13 48.8 0.3 1.9e-11 44.2 0.3 2.0 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Kinesin PF00225.23 CDJ82343.1 - 1e-104 350.1 0.9 1e-104 350.1 0.9 2.9 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ82343.1 - 2.9e-23 82.5 0.1 2.9e-23 82.5 0.1 3.4 3 1 0 3 3 3 1 Microtubule binding DUF4094 PF13334.6 CDJ82343.1 - 0.11 13.0 0.1 0.11 13.0 0.1 5.3 4 2 2 6 6 6 0 Domain of unknown function (DUF4094) Pox_A_type_inc PF04508.12 CDJ82343.1 - 4.9 7.2 22.8 0.54 10.2 0.1 5.8 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat YvrJ PF12841.7 CDJ82343.1 - 9.1 5.9 7.6 14 5.4 0.3 3.4 3 0 0 3 3 3 0 YvrJ protein family Snf7 PF03357.21 CDJ82344.1 - 1.9e-32 112.2 18.4 2.7e-32 111.8 18.4 1.1 1 0 0 1 1 1 1 Snf7 HrpE PF06188.12 CDJ82344.1 - 0.0081 16.1 1.4 0.031 14.1 0.0 2.2 2 1 1 3 3 3 1 HrpE/YscL/FliH and V-type ATPase subunit E GTP-bdg_M PF16360.5 CDJ82344.1 - 0.031 14.9 4.3 0.031 14.9 4.3 2.3 1 1 2 3 3 3 0 GTP-binding GTPase Middle Region CENP-Q PF13094.6 CDJ82344.1 - 0.035 14.3 14.6 0.05 13.8 11.8 2.0 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3585 PF12130.8 CDJ82344.1 - 0.057 13.6 9.5 0.076 13.1 8.9 1.6 1 1 0 1 1 1 0 Bivalent Mical/EHBP Rab binding domain Exonuc_VII_L PF02601.15 CDJ82344.1 - 1.4 8.4 6.4 2.1 7.8 6.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc24 PF08286.11 CDJ82344.1 - 1.5 9.1 10.1 21 5.4 6.6 2.5 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 DMPK_coil PF08826.10 CDJ82344.1 - 8.3 6.6 17.7 3.9 7.7 0.1 2.9 3 0 0 3 3 3 0 DMPK coiled coil domain like Exo_endo_phos PF03372.23 CDJ82345.1 - 5e-14 52.4 0.0 6e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CDJ82345.1 - 0.001 18.9 0.0 0.003 17.4 0.0 1.8 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase RRM_1 PF00076.22 CDJ82346.1 - 5.4e-24 83.8 0.1 6.1e-24 83.6 0.1 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ82346.1 - 0.0012 18.4 0.0 0.0014 18.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ82346.1 - 0.0043 16.9 0.0 0.0092 15.8 0.0 1.5 1 1 0 1 1 1 1 Occluded RNA-recognition motif Pyr_redox_dim PF02852.22 CDJ82346.1 - 0.041 14.1 0.0 0.042 14.1 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Peptidase_S80 PF07230.11 CDJ82346.1 - 0.048 11.9 0.1 0.052 11.8 0.1 1.2 1 1 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) RRM_7 PF16367.5 CDJ82346.1 - 0.18 11.9 0.0 0.36 11.0 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif RRM_1 PF00076.22 CDJ82347.1 - 2e-24 85.2 0.1 2.4e-24 84.9 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ82347.1 - 0.00047 19.8 0.0 0.0005 19.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ82347.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif Peptidase_S80 PF07230.11 CDJ82347.1 - 0.11 10.8 0.1 0.1 10.8 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) RRM_7 PF16367.5 CDJ82347.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif RRM_1 PF00076.22 CDJ82348.1 - 4.6e-23 80.8 0.1 5.6e-23 80.5 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ82348.1 - 0.0021 17.6 0.0 0.0024 17.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ82348.1 - 0.02 14.8 0.0 0.045 13.6 0.0 1.6 1 1 0 1 1 1 0 Occluded RNA-recognition motif PHM7_cyt PF14703.6 CDJ82348.1 - 0.18 12.1 0.0 11 6.3 0.0 2.0 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter MULE PF10551.9 CDJ82349.1 - 0.0013 19.1 0.0 0.0044 17.4 0.0 2.0 1 0 0 1 1 1 1 MULE transposase domain zf-C2H2_4 PF13894.6 CDJ82349.1 - 0.022 15.6 0.3 0.022 15.6 0.3 3.2 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 CDJ82349.1 - 0.025 14.4 0.1 0.098 12.5 0.1 2.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) zf-C2H2_6 PF13912.6 CDJ82349.1 - 0.032 14.2 0.3 0.079 13.0 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 CDJ82349.1 - 0.097 13.2 0.2 0.26 11.8 0.2 1.7 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain BNIP3 PF06553.12 CDJ82350.1 - 8.7e-11 41.9 6.2 8.4e-10 38.6 3.8 2.8 1 1 1 2 2 2 1 BNIP3 LURAP PF14854.6 CDJ82350.1 - 0.015 15.3 0.1 0.029 14.3 0.1 1.4 1 0 0 1 1 1 0 Leucine rich adaptor protein UPF0154 PF03672.13 CDJ82350.1 - 0.35 10.9 0.9 0.64 10.1 0.2 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) zf-TAZ PF02135.16 CDJ82351.1 - 1.8e-07 31.5 5.6 3.7e-07 30.5 5.6 1.5 1 0 0 1 1 1 1 TAZ zinc finger Toxin_13 PF07822.11 CDJ82351.1 - 3.8 7.7 9.4 0.15 12.3 0.5 3.0 4 0 0 4 4 4 0 Neurotoxin B-IV-like protein HEAT_EZ PF13513.6 CDJ82353.1 - 7.2e-06 26.4 0.2 4.2 8.0 0.0 4.7 4 1 1 5 5 5 2 HEAT-like repeat Arm PF00514.23 CDJ82353.1 - 1.1e-05 25.3 15.7 0.11 12.6 0.2 7.5 8 2 0 8 8 8 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CDJ82353.1 - 0.00027 21.2 0.1 1.4 9.4 0.0 3.5 2 2 0 2 2 2 2 HEAT repeats IBN_N PF03810.19 CDJ82353.1 - 0.0057 16.6 0.0 2.5 8.1 0.0 3.1 3 1 0 3 3 3 1 Importin-beta N-terminal domain RICTOR_N PF14664.6 CDJ82353.1 - 0.044 12.8 0.3 0.087 11.8 0.1 1.6 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term HEAT_PBS PF03130.16 CDJ82353.1 - 0.36 11.6 4.7 39 5.3 0.0 4.9 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat RICTOR_V PF14668.6 CDJ82353.1 - 1.3 9.3 7.9 32 4.9 0.5 4.7 4 2 3 7 7 7 0 Rapamycin-insensitive companion of mTOR, domain 5 Wbp11 PF09429.10 CDJ82355.1 - 0.027 14.8 1.2 0.38 11.2 0.4 2.1 1 1 1 2 2 2 0 WW domain binding protein 11 Histone PF00125.24 CDJ82356.1 - 1.4e-06 28.7 1.3 1.4e-06 28.7 1.3 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 PIN_4 PF13638.6 CDJ82356.1 - 0.047 14.0 0.8 0.077 13.3 0.5 1.5 1 1 0 1 1 1 0 PIN domain Branch PF02485.21 CDJ82357.1 - 8.7e-12 45.1 0.0 9.7e-12 44.9 0.0 1.0 1 0 0 1 1 1 1 Core-2/I-Branching enzyme zf-BED PF02892.15 CDJ82358.1 - 0.00016 21.6 0.4 0.0003 20.7 0.4 1.5 1 0 0 1 1 1 1 BED zinc finger MecA PF05389.12 CDJ82358.1 - 0.0054 16.4 8.0 0.012 15.2 8.0 1.6 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) UPF0560 PF10577.9 CDJ82358.1 - 0.019 13.5 19.3 0.036 12.6 19.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Peptidase_S49_N PF08496.10 CDJ82358.1 - 0.047 13.7 10.8 0.087 12.9 10.8 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FPN1 PF06963.12 CDJ82358.1 - 0.052 12.1 3.0 0.075 11.6 3.0 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF853 PF05872.12 CDJ82358.1 - 0.077 11.6 9.4 0.11 11.1 9.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) MAJIN PF15077.6 CDJ82358.1 - 0.26 11.1 7.9 0.7 9.6 7.9 1.7 1 0 0 1 1 1 0 Membrane-anchored junction protein AAA_23 PF13476.6 CDJ82358.1 - 0.34 11.4 17.3 0.18 12.3 14.8 1.8 2 0 0 2 2 2 0 AAA domain EIIBC-GUT_N PF03612.14 CDJ82358.1 - 0.35 10.6 8.6 2 8.1 9.3 1.9 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Peroxin-13_N PF04088.13 CDJ82358.1 - 0.46 10.7 6.4 1.1 9.5 6.4 1.6 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Exonuc_VII_L PF02601.15 CDJ82358.1 - 0.58 9.7 17.7 1.2 8.6 17.7 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pinin_SDK_memA PF04696.13 CDJ82358.1 - 0.61 10.1 25.0 1.5 8.9 25.0 1.6 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region zf-ZPR1 PF03367.13 CDJ82358.1 - 0.81 9.5 6.9 19 5.1 7.1 2.3 2 0 0 2 2 2 0 ZPR1 zinc-finger domain Muted PF14942.6 CDJ82358.1 - 0.93 9.8 16.0 2 8.8 16.0 1.6 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein zf-C2H2_4 PF13894.6 CDJ82358.1 - 0.94 10.5 2.7 2.5 9.2 2.7 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger SID-1_RNA_chan PF13965.6 CDJ82358.1 - 0.99 7.7 4.5 1.4 7.3 4.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CTU2 PF10288.9 CDJ82358.1 - 1.2 9.5 17.0 0.053 13.8 9.7 2.5 3 0 0 3 3 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Dynactin_p62 PF05502.13 CDJ82358.1 - 1.2 7.8 16.3 2.3 6.9 16.3 1.4 1 0 0 1 1 1 0 Dynactin p62 family FTO_NTD PF12933.7 CDJ82358.1 - 1.2 8.3 11.0 2.8 7.1 11.0 1.5 1 0 0 1 1 1 0 FTO catalytic domain Bud13 PF09736.9 CDJ82358.1 - 1.3 9.4 14.8 2.8 8.3 14.8 1.6 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex zf-H2C2_5 PF13909.6 CDJ82358.1 - 1.5 8.7 4.8 3.3 7.6 4.8 1.6 1 0 0 1 1 1 0 C2H2-type zinc-finger domain V_ATPase_I PF01496.19 CDJ82358.1 - 1.5 6.7 12.5 2 6.2 12.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Endonuc_Holl PF10107.9 CDJ82358.1 - 1.7 8.5 7.7 3.1 7.6 7.7 1.4 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase ALMT PF11744.8 CDJ82358.1 - 1.9 7.2 13.2 3.4 6.4 13.2 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter MCU PF04678.13 CDJ82358.1 - 2.7 8.1 9.8 1.9 8.6 7.9 1.7 2 0 0 2 2 1 0 Mitochondrial calcium uniporter Connexin PF00029.19 CDJ82358.1 - 2.8 7.7 5.8 4.5 7.0 5.8 1.3 1 0 0 1 1 1 0 Connexin ABC2_membrane_3 PF12698.7 CDJ82358.1 - 3 6.9 6.1 6.6 5.7 6.1 1.7 1 0 0 1 1 1 0 ABC-2 family transporter protein Activator_LAG-3 PF11498.8 CDJ82358.1 - 3.3 6.6 52.8 6.4 5.6 52.8 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Serinc PF03348.15 CDJ82358.1 - 3.9 6.3 5.2 5.6 5.8 5.2 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) CSG2 PF16965.5 CDJ82358.1 - 4.3 6.2 6.0 7.1 5.5 6.0 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator RR_TM4-6 PF06459.12 CDJ82358.1 - 4.6 7.0 19.1 0.04 13.8 10.6 1.8 2 1 0 2 2 1 0 Ryanodine Receptor TM 4-6 PepSY_TM PF03929.16 CDJ82358.1 - 7.3 6.2 9.6 19 4.8 9.6 1.6 1 0 0 1 1 1 0 PepSY-associated TM region O-antigen_lig PF13425.6 CDJ82358.1 - 7.7 5.2 7.1 11 4.6 7.1 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DNA_pol_A_exo1 PF01612.20 CDJ82359.1 - 2e-10 40.7 0.0 5e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 3'-5' exonuclease DUF3456 PF11938.8 CDJ82360.1 - 3.3e-15 56.9 2.8 7.2e-07 29.8 2.9 2.3 1 1 1 2 2 2 2 TLR4 regulator and MIR-interacting MSAP EGF_CA PF07645.15 CDJ82360.1 - 4.2e-09 36.5 12.4 4.2e-09 36.5 12.4 4.5 4 1 0 4 4 4 1 Calcium-binding EGF domain EGF PF00008.27 CDJ82360.1 - 0.0013 19.0 5.4 0.0013 19.0 5.4 4.0 3 2 0 3 3 3 2 EGF-like domain Plasmod_Pvs28 PF06247.11 CDJ82360.1 - 0.0016 18.7 11.0 0.0016 18.7 11.0 3.2 3 0 0 3 3 3 1 Pvs28 EGF domain hEGF PF12661.7 CDJ82360.1 - 0.0022 18.6 0.7 0.0022 18.6 0.7 4.7 5 1 0 5 5 5 2 Human growth factor-like EGF cEGF PF12662.7 CDJ82360.1 - 0.0024 17.7 18.5 0.031 14.2 0.3 3.9 3 0 0 3 3 3 2 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 CDJ82360.1 - 0.0039 17.2 9.9 0.0039 17.2 9.9 3.8 3 0 0 3 3 3 1 MSP1 EGF domain 1 FXa_inhibition PF14670.6 CDJ82360.1 - 0.0045 17.3 8.4 0.0045 17.3 8.4 4.6 3 1 1 4 4 4 1 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 CDJ82360.1 - 0.01 16.0 10.3 0.01 16.0 10.3 3.8 3 0 0 3 3 3 0 EGF domain Laminin_EGF PF00053.24 CDJ82360.1 - 0.017 15.3 15.0 0.017 15.3 15.0 5.0 4 1 1 5 5 5 0 Laminin EGF domain CAP PF00188.26 CDJ82362.1 - 2.8e-36 125.1 13.9 8.3e-18 65.4 6.0 2.2 2 0 0 2 2 2 2 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ82362.1 - 1.1e-05 25.7 3.4 0.088 13.1 0.1 2.8 2 1 0 2 2 2 2 Ancylostoma-associated secreted protein related RPN5_C PF18098.1 CDJ82362.1 - 0.033 14.3 0.1 0.077 13.1 0.1 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN5 C-terminal domain DUF956 PF06115.11 CDJ82362.1 - 0.095 12.4 0.4 0.81 9.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF956) ATP-synt_F6 PF05511.11 CDJ82362.1 - 0.1 13.0 0.0 16 6.0 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 Metallothio PF00131.20 CDJ82362.1 - 0.14 12.3 21.9 1.5 9.0 6.6 3.1 2 0 0 2 2 2 0 Metallothionein Metallothio_Euk PF12749.7 CDJ82362.1 - 0.56 10.4 24.8 0.63 10.2 5.6 3.0 2 1 0 2 2 2 0 Eukaryotic metallothionein Metallothio_PEC PF02068.16 CDJ82362.1 - 1.5 9.2 26.5 0.85 10.0 9.7 2.6 2 0 0 2 2 2 0 Plant PEC family metallothionein DnaJ PF00226.31 CDJ82364.1 - 1.8e-23 82.4 0.9 1.8e-23 82.4 0.9 3.0 3 0 0 3 3 3 1 DnaJ domain TrbH PF07283.11 CDJ82364.1 - 0.0025 18.0 0.1 0.0043 17.2 0.1 1.4 1 0 0 1 1 1 1 Conjugal transfer protein TrbH Talin_middle PF09141.10 CDJ82364.1 - 0.0048 16.9 1.3 0.28 11.2 0.2 2.2 2 0 0 2 2 2 2 Talin, middle domain ALMT PF11744.8 CDJ82364.1 - 0.092 11.6 1.2 0.11 11.3 1.2 1.3 1 1 0 1 1 1 0 Aluminium activated malate transporter Auxin_canalis PF05703.11 CDJ82364.1 - 3.3 7.6 5.6 8 6.3 5.6 1.7 1 1 0 1 1 1 0 Auxin canalisation Fer4 PF00037.27 CDJ82365.1 - 3.7e-14 51.9 16.4 1.3e-08 34.2 3.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 CDJ82365.1 - 1.9e-12 47.6 9.5 3.2e-12 46.8 9.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 CDJ82365.1 - 1.7e-10 41.7 7.4 1.9e-05 25.5 0.6 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 CDJ82365.1 - 4.3e-10 39.6 32.7 1.8e-06 28.0 12.6 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 CDJ82365.1 - 6.8e-09 35.8 9.3 1.5e-08 34.7 9.3 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 CDJ82365.1 - 4.1e-08 33.2 21.6 3.1e-05 24.0 13.2 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 CDJ82365.1 - 1.7e-07 31.6 19.5 2.5e-05 24.6 10.5 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 CDJ82365.1 - 3.7e-07 29.9 18.4 0.00041 20.3 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 CDJ82365.1 - 7.8e-07 28.8 12.0 0.0016 18.4 1.9 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 CDJ82365.1 - 5.5e-06 26.5 11.7 0.00052 20.3 2.5 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 CDJ82365.1 - 0.0008 19.9 14.0 0.022 15.3 12.9 2.7 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 CDJ82365.1 - 0.0029 18.1 14.1 0.14 12.7 2.2 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 CDJ82365.1 - 0.0089 16.9 16.5 0.015 16.2 4.2 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_18 PF13746.6 CDJ82365.1 - 0.054 13.7 8.9 3.7 7.8 1.6 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 CDJ82365.1 - 0.062 13.5 7.4 0.57 10.5 0.3 2.7 2 1 1 3 3 3 0 c-SKI Smad4 binding domain Fer4_22 PF17179.4 CDJ82365.1 - 0.75 10.7 11.1 1.8 9.5 1.1 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 CDJ82365.1 - 1.4 9.1 6.4 1.5 9.0 0.6 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S EPF PF17181.4 CDJ82365.1 - 1.7 8.7 6.9 1.3 9.1 1.6 2.3 2 0 0 2 2 2 0 Epidermal patterning factor proteins Fer4 PF00037.27 CDJ82366.1 - 1.3e-14 53.3 17.3 5.1e-09 35.6 4.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 CDJ82366.1 - 1.7e-13 50.9 10.0 2.9e-13 50.2 10.0 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 CDJ82366.1 - 5.2e-10 40.1 8.2 3.6e-05 24.6 0.8 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 CDJ82366.1 - 6.3e-10 39.0 32.9 2.8e-06 27.4 12.7 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 CDJ82366.1 - 1.1e-09 38.2 21.3 9.5e-07 28.8 12.5 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 CDJ82366.1 - 2.3e-09 37.2 7.7 4.3e-09 36.4 7.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 CDJ82366.1 - 1.8e-07 30.9 17.7 0.00035 20.5 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 CDJ82366.1 - 7.9e-07 29.4 21.2 7e-05 23.2 11.5 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 CDJ82366.1 - 9.1e-07 28.6 12.1 0.002 18.1 1.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 CDJ82366.1 - 3.9e-06 26.9 10.7 0.00026 21.3 1.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 CDJ82366.1 - 8.8e-05 23.0 11.4 0.0082 16.7 12.4 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 CDJ82366.1 - 0.0039 17.7 14.9 0.23 12.0 2.9 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 CDJ82366.1 - 0.0068 17.3 16.5 0.013 16.4 4.2 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.10 CDJ82366.1 - 0.0073 16.5 4.8 0.57 10.4 0.5 2.3 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 CDJ82366.1 - 0.048 13.9 9.1 3.8 7.7 1.6 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 CDJ82366.1 - 0.19 11.9 5.7 1.4 9.1 0.6 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 CDJ82366.1 - 0.46 11.4 11.6 2.2 9.2 1.8 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.27 CDJ82367.1 - 1.4e-14 53.2 17.3 5.2e-09 35.6 4.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 CDJ82367.1 - 1.1e-13 51.6 9.7 1.6e-13 51.0 9.7 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 CDJ82367.1 - 1.8e-11 44.8 4.8 1.3e-05 26.0 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 CDJ82367.1 - 1.9e-10 40.7 3.6 0.00018 21.6 0.5 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 CDJ82367.1 - 3.6e-09 36.6 9.7 5.6e-09 36.0 9.7 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 CDJ82367.1 - 5.7e-09 36.0 22.1 3e-06 27.2 13.2 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 CDJ82367.1 - 1.5e-07 31.8 19.7 5.8e-05 23.4 11.6 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 CDJ82367.1 - 2e-07 30.8 17.7 0.00035 20.5 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 CDJ82367.1 - 8e-07 28.8 11.9 0.0017 18.3 1.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 CDJ82367.1 - 7.4e-06 26.1 11.3 0.00045 20.5 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 CDJ82367.1 - 0.00015 22.2 11.8 0.012 16.2 12.7 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 CDJ82367.1 - 0.0055 17.2 14.9 0.24 12.0 2.9 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 CDJ82367.1 - 0.0075 16.5 4.9 0.44 10.8 0.3 2.3 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_3 PF12798.7 CDJ82367.1 - 0.0075 17.1 16.5 0.013 16.4 4.2 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_18 PF13746.6 CDJ82367.1 - 0.068 13.4 9.4 12 6.1 9.5 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain ETF_QO PF05187.13 CDJ82367.1 - 0.35 11.0 6.0 1.3 9.1 0.7 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 CDJ82367.1 - 0.93 10.4 11.7 2.3 9.1 1.7 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain A_deamin PF02137.18 CDJ82368.1 - 4.8e-87 292.5 0.0 2.1e-86 290.4 0.0 2.0 2 0 0 2 2 2 1 Adenosine-deaminase (editase) domain Myb_DNA-bind_7 PF15963.5 CDJ82368.1 - 6.1e-06 26.0 0.2 2e-05 24.4 0.2 1.8 1 0 0 1 1 1 1 Myb DNA-binding like Cas_GSU0053 PF09617.10 CDJ82368.1 - 0.013 15.5 0.7 0.032 14.2 0.7 1.6 1 0 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) dsrm PF00035.26 CDJ82368.1 - 0.019 15.6 0.0 0.049 14.3 0.0 1.8 1 0 0 1 1 1 0 Double-stranded RNA binding motif Bap31_Bap29_C PF18035.1 CDJ82368.1 - 1.1 9.4 3.2 12 6.0 0.3 2.7 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain WD40 PF00400.32 CDJ82369.1 - 1e-33 114.8 16.2 2.7e-06 28.0 0.2 7.4 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ82369.1 - 7.2e-09 35.8 0.1 0.055 13.8 0.0 5.0 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ82369.1 - 3.1e-08 33.0 0.2 0.0024 16.9 0.0 3.3 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CDJ82369.1 - 0.00082 18.8 0.0 0.0017 17.8 0.0 1.4 1 1 1 2 2 2 1 WD40-like domain Nbas_N PF15492.6 CDJ82369.1 - 0.019 14.3 0.1 1.2 8.4 0.0 2.9 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 CDJ82369.1 - 0.029 13.0 0.0 0.056 12.1 0.0 1.5 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CDJ82369.1 - 0.16 10.7 0.1 1.6 7.4 0.1 2.3 1 1 0 1 1 1 0 Nup133 N terminal like BPL_LplA_LipB PF03099.19 CDJ82370.1 - 0.00013 21.9 0.0 0.00056 19.8 0.0 2.0 2 1 0 2 2 2 1 Biotin/lipoate A/B protein ligase family HSP90 PF00183.18 CDJ82371.1 - 5.1e-92 309.4 9.6 6.8e-90 302.4 5.1 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 CDJ82371.1 - 2.3e-12 46.9 0.1 4.3e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDJ82371.1 - 6.3e-09 36.3 0.1 1.2e-08 35.4 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HEPN_RiboL-PSP PF18735.1 CDJ82371.1 - 0.13 12.2 2.8 0.41 10.5 0.0 2.4 2 0 0 2 2 2 0 RiboL-PSP-HEPN DER1 PF04511.15 CDJ82372.1 - 2.6e-75 252.6 17.3 3e-75 252.4 17.3 1.0 1 0 0 1 1 1 1 Der1-like family DUF3040 PF11239.8 CDJ82372.1 - 4.8 7.5 6.6 0.65 10.3 2.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Oleosin PF01277.17 CDJ82372.1 - 7.3 6.4 7.2 2.3 8.0 0.2 2.3 1 1 1 2 2 2 0 Oleosin KIF1B PF12423.8 CDJ82373.1 - 1.4e-07 31.9 1.9 3.8e-07 30.4 1.9 1.8 1 0 0 1 1 1 1 Kinesin protein 1B MTS PF05175.14 CDJ82374.1 - 8.3e-19 67.8 0.0 1.2e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CDJ82374.1 - 5.3e-12 46.3 0.0 1e-11 45.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ82374.1 - 1.3e-11 44.5 0.0 1.8e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 CDJ82374.1 - 3.4e-10 39.9 0.0 4.8e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.12 CDJ82374.1 - 8.1e-09 36.0 0.0 1.4e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CDJ82374.1 - 1.1e-08 34.8 0.3 1.5e-08 34.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 CDJ82374.1 - 3.2e-08 33.4 0.0 3.8e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 CDJ82374.1 - 9.7e-08 32.7 0.0 2.6e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.16 CDJ82374.1 - 1e-06 28.2 0.0 1.2e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_15 PF09445.10 CDJ82374.1 - 2.1e-06 27.4 0.1 2.9e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 CDJ82374.1 - 9.3e-06 25.6 0.2 1.5e-05 24.9 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ82374.1 - 1.2e-05 24.8 0.0 1.4e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family N6_Mtase PF02384.16 CDJ82374.1 - 1.3e-05 24.6 0.0 1.7e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase AviRa PF11599.8 CDJ82374.1 - 5.7e-05 22.7 0.6 0.0015 18.0 0.2 2.2 1 1 1 2 2 2 1 RRNA methyltransferase AviRa Methyltransf_9 PF08003.11 CDJ82374.1 - 0.0002 20.4 0.1 0.00028 19.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Met_10 PF02475.16 CDJ82374.1 - 0.00026 20.8 0.0 0.00038 20.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Spermine_synth PF01564.17 CDJ82374.1 - 0.0003 20.2 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 CDJ82374.1 - 0.00074 19.4 0.0 0.00099 19.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CDJ82374.1 - 0.0015 18.6 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 CDJ82374.1 - 0.0031 17.2 0.0 0.0047 16.6 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F CMAS PF02353.20 CDJ82374.1 - 0.0057 16.0 0.0 0.0073 15.6 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase TPMT PF05724.11 CDJ82374.1 - 0.0068 16.1 0.1 0.0099 15.6 0.1 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_16 PF10294.9 CDJ82374.1 - 0.011 15.4 1.2 0.031 14.0 0.1 1.9 2 0 0 2 2 2 0 Lysine methyltransferase Methyltransf_4 PF02390.17 CDJ82374.1 - 0.014 14.9 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DOT1 PF08123.13 CDJ82374.1 - 0.019 14.5 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.19 CDJ82374.1 - 0.019 14.7 0.0 0.026 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) rRNA_methylase PF06962.12 CDJ82374.1 - 0.093 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative rRNA methylase N6-adenineMlase PF10237.9 CDJ82374.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase RVT_1 PF00078.27 CDJ82375.1 - 9.2e-06 25.3 0.1 1.5e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GIY-YIG PF01541.24 CDJ82375.1 - 0.00025 21.2 0.0 0.00044 20.5 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain SNF PF00209.18 CDJ82376.1 - 3.5e-08 32.6 42.7 5.2e-08 32.0 42.7 1.2 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Nop14 PF04147.12 CDJ82379.1 - 5.2e-189 630.5 37.7 5.2e-189 630.5 37.7 1.8 2 0 0 2 2 2 1 Nop14-like family SIKE PF05769.11 CDJ82379.1 - 4.9e-18 65.7 11.2 4.9e-18 65.7 11.2 2.7 3 0 0 3 3 3 1 SIKE family SMAP PF15477.6 CDJ82379.1 - 0.068 14.1 1.2 2.1 9.3 0.1 3.1 2 0 0 2 2 2 0 Small acidic protein family TSP_1 PF00090.19 CDJ82380.1 - 1.7e-45 153.0 203.2 1.2e-10 41.4 11.7 14.4 14 1 0 14 14 14 13 Thrombospondin type 1 domain Aminoglyc_resit PF10706.9 CDJ82381.1 - 0.06 13.1 0.4 0.076 12.7 0.4 1.1 1 0 0 1 1 1 0 Aminoglycoside-2''-adenylyltransferase Ig_3 PF13927.6 CDJ82383.1 - 3.7e-70 232.5 1.9 1.9e-10 41.2 0.0 10.2 10 0 0 10 10 10 9 Immunoglobulin domain I-set PF07679.16 CDJ82383.1 - 5.3e-53 177.1 0.0 2.3e-08 34.0 0.0 9.6 10 0 0 10 10 10 7 Immunoglobulin I-set domain Ig_2 PF13895.6 CDJ82383.1 - 6e-47 157.9 1.9 1.1e-07 32.0 0.0 9.5 9 0 0 9 9 9 9 Immunoglobulin domain C2-set_2 PF08205.12 CDJ82383.1 - 8.4e-39 131.5 3.1 1.8e-09 37.5 0.0 7.2 6 1 0 6 6 6 5 CD80-like C2-set immunoglobulin domain ig PF00047.25 CDJ82383.1 - 7.2e-35 119.0 0.6 5.1e-06 26.6 0.0 9.0 8 1 0 8 8 8 7 Immunoglobulin domain V-set PF07686.17 CDJ82383.1 - 3e-14 53.1 0.1 0.00011 22.3 0.0 8.2 8 1 1 9 9 9 2 Immunoglobulin V-set domain fn3 PF00041.21 CDJ82383.1 - 1.9e-12 47.3 0.1 8e-12 45.3 0.0 2.2 2 0 0 2 2 2 1 Fibronectin type III domain C1-set PF07654.15 CDJ82383.1 - 4.4e-09 36.6 0.6 0.29 11.5 0.1 6.0 5 0 0 5 5 5 2 Immunoglobulin C1-set domain BiPBP_C PF06832.12 CDJ82383.1 - 2.8e-05 24.1 0.3 1 9.4 0.0 5.0 6 0 0 6 6 6 2 Penicillin-Binding Protein C-terminus Family Ig_5 PF16681.5 CDJ82383.1 - 7.5e-05 23.1 0.0 0.04 14.3 0.0 5.0 5 0 0 5 5 5 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 CDJ82383.1 - 7.7e-05 22.9 1.3 0.066 13.5 0.0 4.8 5 0 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain Lep_receptor_Ig PF06328.11 CDJ82383.1 - 0.032 14.2 1.4 88 3.2 0.0 5.0 5 0 0 5 5 5 0 Ig-like C2-type domain ShK PF01549.24 CDJ82384.1 - 3e-06 27.7 17.8 3.9e-05 24.1 4.2 2.7 3 0 0 3 3 3 2 ShK domain-like LLC1 PF14945.6 CDJ82384.1 - 1.7 9.2 5.3 0.3 11.7 1.8 1.6 1 1 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein SOG2 PF10428.9 CDJ82384.1 - 2.6 7.2 11.5 3.1 6.9 11.5 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein FSA_C PF10479.9 CDJ82384.1 - 2.9 5.9 8.6 3.5 5.6 8.6 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Glyco_hydro_25 PF01183.20 CDJ82385.1 - 1.5e-08 35.1 0.4 3.3e-08 33.9 0.7 1.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 25 DUF1906 PF08924.11 CDJ82385.1 - 6.7e-05 23.1 0.9 8.3e-05 22.8 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1906) DUF4830 PF16112.5 CDJ82385.1 - 0.017 15.6 0.4 0.031 14.7 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4830) DOMON PF03351.17 CDJ82388.1 - 1.7e-20 73.5 0.0 2.1e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 DOMON domain DOMON PF03351.17 CDJ82389.1 - 1.4e-26 93.2 0.0 5.5e-12 46.0 0.0 2.2 2 0 0 2 2 2 2 DOMON domain DOMON PF03351.17 CDJ82390.1 - 6.1e-12 45.8 0.0 7.6e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 DOMON domain DOMON PF03351.17 CDJ82391.1 - 8.4e-09 35.7 0.0 9.8e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 DOMON domain DUF898 PF05987.13 CDJ82391.1 - 0.14 11.2 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) AAA_2 PF07724.14 CDJ82392.1 - 1.6e-40 139.0 0.4 3.9e-40 137.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 CDJ82392.1 - 8.2e-13 48.9 0.0 1.7e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CDJ82392.1 - 3.5e-12 46.2 0.2 1.6e-11 44.1 0.1 2.1 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CDJ82392.1 - 3.6e-06 27.0 0.0 1.2e-05 25.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 CDJ82392.1 - 8.1e-06 25.1 0.0 1.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 CDJ82392.1 - 2e-05 24.1 0.2 0.048 13.0 0.0 2.9 3 1 1 4 4 4 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CDJ82392.1 - 3.7e-05 24.0 0.8 0.0032 17.7 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ82392.1 - 0.00027 21.3 0.6 0.0061 17.0 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain Sigma54_activat PF00158.26 CDJ82392.1 - 0.00077 19.2 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 CDJ82392.1 - 0.00095 18.9 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 CDJ82392.1 - 0.0018 18.3 0.0 0.0057 16.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CDJ82392.1 - 0.0021 18.6 0.3 0.0085 16.6 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_18 PF13238.6 CDJ82392.1 - 0.012 16.1 0.8 0.079 13.5 0.0 2.7 4 0 0 4 4 3 0 AAA domain AAA_21 PF13304.6 CDJ82392.1 - 0.013 15.4 0.0 0.032 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 CDJ82392.1 - 0.021 14.8 0.0 0.31 10.9 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 CDJ82392.1 - 0.032 13.7 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RuvB_N PF05496.12 CDJ82392.1 - 0.033 13.9 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 CDJ82392.1 - 0.057 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 CDJ82392.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CDJ82392.1 - 0.13 12.5 0.5 0.55 10.5 0.1 2.4 2 1 1 3 3 3 0 AAA domain PduV-EutP PF10662.9 CDJ82392.1 - 0.14 11.9 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 CDJ82392.1 - 0.15 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cytidylate_kin PF02224.18 CDJ82392.1 - 0.36 10.5 2.0 6.2 6.5 0.0 2.9 3 1 0 3 3 3 0 Cytidylate kinase Zona_pellucida PF00100.23 CDJ82396.1 - 1.4e-08 34.8 0.0 1.9e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Amidinotransf PF02274.17 CDJ82397.1 - 5.8e-28 98.0 0.0 6.5e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Amidinotransferase PAD_porph PF04371.15 CDJ82397.1 - 0.12 11.6 0.0 1.9 7.7 0.0 2.5 2 1 0 2 2 2 0 Porphyromonas-type peptidyl-arginine deiminase ATP-synt PF00231.19 CDJ82400.1 - 4e-80 269.5 5.2 4.6e-80 269.3 5.2 1.0 1 0 0 1 1 1 1 ATP synthase T2SSF PF00482.23 CDJ82401.1 - 0.043 13.8 1.5 0.17 11.9 0.3 2.6 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F Tropomyosin PF00261.20 CDJ82401.1 - 0.44 9.9 18.9 0.021 14.2 11.4 2.1 2 0 0 2 2 2 0 Tropomyosin DivIC PF04977.15 CDJ82401.1 - 2.9 7.7 5.8 15 5.4 0.2 3.0 2 1 0 2 2 2 0 Septum formation initiator V_ATPase_I PF01496.19 CDJ82401.1 - 7.2 4.4 7.5 2.4 6.0 4.9 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Tad_C PF09977.9 CDJ82402.1 - 0.0084 17.3 1.0 0.014 16.6 1.0 1.3 1 0 0 1 1 1 1 Putative Tad-like Flp pilus-assembly DUF3337 PF11816.8 CDJ82402.1 - 0.049 13.5 1.1 0.076 12.9 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) SKA1 PF07160.12 CDJ82402.1 - 0.05 13.4 2.9 0.085 12.7 2.9 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DDE_Tnp_1_2 PF13586.6 CDJ82402.1 - 0.086 13.2 0.9 0.17 12.3 0.2 1.8 2 0 0 2 2 2 0 Transposase DDE domain Ground-like PF04155.18 CDJ82403.1 - 2e-10 41.2 0.1 2.9e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 Ground-like domain cwf18 PF08315.12 CDJ82404.1 - 2.3e-30 106.0 12.8 2.9e-30 105.7 12.8 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor CdvA PF18822.1 CDJ82404.1 - 0.019 14.8 10.5 0.34 10.7 0.5 2.3 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DUF1104 PF06518.11 CDJ82404.1 - 0.034 14.5 10.6 1.7 9.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) SIR4_SID PF16991.5 CDJ82404.1 - 7.7 6.5 10.0 22 5.0 10.0 1.8 1 1 0 1 1 1 0 Sir4 SID domain Vfa1 PF08432.10 CDJ82404.1 - 7.9 6.8 13.3 16 5.8 0.1 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 CAP PF00188.26 CDJ82405.1 - 7.8e-14 52.6 3.7 1.1e-13 52.1 3.7 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ82405.1 - 0.0078 16.5 1.4 0.0078 16.5 1.4 1.8 3 0 0 3 3 3 1 Ancylostoma-associated secreted protein related Nodulin_late PF07127.11 CDJ82405.1 - 0.069 13.5 2.4 0.069 13.5 2.4 2.3 3 0 0 3 3 3 0 Late nodulin protein CAP PF00188.26 CDJ82406.1 - 3.7e-17 63.3 5.0 5.1e-17 62.9 5.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family P4Ha_N PF08336.11 CDJ82407.1 - 1.3e-32 112.6 1.0 3e-32 111.4 1.0 1.6 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 CDJ82407.1 - 6.6e-12 46.2 1.1 1.6e-11 44.9 0.4 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 CDJ82407.1 - 0.024 14.7 0.3 0.12 12.5 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat UvrD-helicase PF00580.21 CDJ82407.1 - 0.076 12.5 3.8 0.19 11.2 1.5 2.1 1 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain P4Ha_N PF08336.11 CDJ82408.1 - 1.8e-16 60.4 3.3 2.1e-16 60.1 3.3 1.0 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF1308 PF07000.11 CDJ82408.1 - 0.017 15.1 0.7 0.026 14.5 0.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1308) DUF885 PF05960.11 CDJ82408.1 - 0.13 11.9 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Cadherin PF00028.17 CDJ82409.1 - 5.4e-114 372.9 8.8 6.7e-20 71.3 0.1 8.1 8 0 0 8 8 8 7 Cadherin domain Laminin_G_2 PF02210.24 CDJ82409.1 - 1e-30 106.9 0.0 5.3e-20 72.3 0.0 3.2 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 CDJ82409.1 - 3.6e-18 66.0 0.0 1.6e-10 41.3 0.0 2.7 2 0 0 2 2 2 2 Laminin G domain Cadherin_2 PF08266.12 CDJ82409.1 - 3.5e-10 39.6 0.4 0.49 10.3 0.0 7.3 7 1 1 8 8 8 2 Cadherin-like Cadherin_3 PF16184.5 CDJ82409.1 - 1.7e-09 37.6 14.0 0.0042 17.1 0.1 7.0 7 0 0 7 7 7 3 Cadherin-like EGF PF00008.27 CDJ82409.1 - 1.7e-05 25.0 7.8 1.7e-05 25.0 7.8 9.5 11 0 0 11 11 9 5 EGF-like domain hEGF PF12661.7 CDJ82409.1 - 0.00081 19.9 2.7 0.00081 19.9 2.7 12.4 14 0 0 14 14 13 1 Human growth factor-like EGF Laminin_G_3 PF13385.6 CDJ82409.1 - 0.0022 18.1 0.0 0.073 13.2 0.0 2.6 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily GAIN PF16489.5 CDJ82409.1 - 0.0072 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Cadherin_4 PF17803.1 CDJ82409.1 - 0.02 15.5 22.4 0.69 10.6 0.0 5.3 6 0 0 6 6 5 0 Bacterial cadherin-like domain RET_CLD1 PF17756.1 CDJ82409.1 - 0.023 15.0 0.0 12 6.1 0.0 4.1 4 0 0 4 4 3 0 RET Cadherin like domain 1 7tm_2 PF00002.24 CDJ82409.1 - 0.026 13.8 21.3 0.045 13.0 21.3 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) DUF1080 PF06439.11 CDJ82409.1 - 0.11 12.5 0.0 2.9 7.9 0.0 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1080) RVT_1 PF00078.27 CDJ82410.1 - 0.00027 20.5 0.0 0.00029 20.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ArfGap PF01412.18 CDJ82411.1 - 7.1e-40 135.7 0.0 1.8e-39 134.4 0.0 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ras PF00071.22 CDJ82411.1 - 2e-06 27.5 0.0 3.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Ras family PH PF00169.29 CDJ82411.1 - 2.9e-06 27.8 0.1 0.048 14.2 0.1 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 CDJ82411.1 - 0.0031 17.9 0.3 0.24 11.8 0.1 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain F-box_4 PF15966.5 CDJ82411.1 - 0.083 12.8 1.3 0.36 10.7 0.0 2.6 3 0 0 3 3 3 0 F-box Roc PF08477.13 CDJ82412.1 - 4.7e-05 23.6 0.1 6.5e-05 23.1 0.1 1.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDJ82412.1 - 0.00022 20.9 0.1 0.00037 20.1 0.1 1.4 1 1 0 1 1 1 1 Ras family SRPRB PF09439.10 CDJ82412.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CDJ82412.1 - 0.15 12.1 0.2 0.18 11.9 0.2 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase PRKCSH-like PF12999.7 CDJ82414.1 - 0.1 12.4 4.0 0.15 11.9 4.0 1.2 1 0 0 1 1 1 0 Glucosidase II beta subunit-like CCDC92 PF14916.6 CDJ82415.1 - 2.9e-07 30.1 0.2 2.9e-07 30.1 0.2 2.6 1 1 0 1 1 1 1 Coiled-coil domain of unknown function Med9 PF07544.13 CDJ82415.1 - 0.0013 18.8 14.7 0.013 15.6 3.7 2.6 1 1 1 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 DUF812 PF05667.11 CDJ82415.1 - 0.0016 17.4 17.3 0.0019 17.2 17.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Fmp27_WPPW PF10359.9 CDJ82415.1 - 0.0022 17.0 5.4 0.0022 17.0 5.4 1.9 2 1 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF4795 PF16043.5 CDJ82415.1 - 0.014 15.0 12.9 0.019 14.6 12.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) MetOD2 PF18548.1 CDJ82415.1 - 0.016 15.3 11.2 0.19 11.8 2.2 2.8 1 1 1 2 2 2 0 Metanogen output domain 2 ZYG-11_interact PF05884.12 CDJ82415.1 - 0.017 14.6 2.2 0.025 14.0 2.2 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 Baculo_PEP_C PF04513.12 CDJ82415.1 - 0.17 11.9 7.0 0.27 11.3 5.9 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_23 PF13476.6 CDJ82415.1 - 0.19 12.2 14.0 0.31 11.5 14.0 1.3 1 0 0 1 1 1 0 AAA domain Golgin_A5 PF09787.9 CDJ82415.1 - 0.35 10.3 29.5 0.64 9.4 15.4 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF948 PF06103.11 CDJ82415.1 - 0.51 10.6 3.1 24 5.3 3.3 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.12 CDJ82415.1 - 0.58 10.8 25.1 0.063 13.9 6.4 3.7 1 1 3 4 4 4 0 SlyX Tweety PF04906.13 CDJ82415.1 - 0.64 8.6 2.4 1.3 7.6 2.4 1.4 1 0 0 1 1 1 0 Tweety DUF1664 PF07889.12 CDJ82415.1 - 0.99 9.5 9.0 2.9 8.0 7.5 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 CDJ82415.1 - 1 9.5 22.0 1 9.5 15.4 2.7 1 1 1 2 2 2 0 Tropomyosin like DUF16 PF01519.16 CDJ82415.1 - 1.1 9.8 20.4 5.2 7.6 13.6 3.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 TMF_DNA_bd PF12329.8 CDJ82415.1 - 1.2 9.2 22.0 0.75 9.8 16.4 3.0 2 2 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2203 PF09969.9 CDJ82415.1 - 2 9.2 17.7 1.8 9.3 0.8 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) eIF3_N PF09440.10 CDJ82415.1 - 2.1 8.8 7.1 0.93 9.9 4.1 1.8 1 1 0 1 1 1 0 eIF3 subunit 6 N terminal domain ABC_tran_CTD PF16326.5 CDJ82415.1 - 2.2 8.6 15.4 8.3 6.7 6.4 3.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF3584 PF12128.8 CDJ82415.1 - 2.3 5.6 23.7 2.9 5.3 23.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HAD_2 PF13419.6 CDJ82415.1 - 2.5 8.2 6.6 1.1 9.3 2.5 1.9 1 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Macoilin PF09726.9 CDJ82415.1 - 2.5 6.5 17.7 3.5 6.1 17.7 1.1 1 0 0 1 1 1 0 Macoilin family NPV_P10 PF05531.12 CDJ82415.1 - 2.7 8.5 7.3 72 3.9 7.0 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TEX13 PF15186.6 CDJ82415.1 - 4.5 6.9 20.4 1.4 8.5 3.0 3.1 2 1 1 3 3 3 0 Testis-expressed sequence 13 protein family COG2 PF06148.11 CDJ82415.1 - 5 7.2 9.3 17 5.5 8.9 2.2 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Fib_alpha PF08702.10 CDJ82415.1 - 8.9 6.5 23.4 7.7 6.7 12.0 2.7 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family ECSIT PF06239.11 CDJ82416.1 - 0.026 13.7 0.0 0.028 13.5 0.0 1.1 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway PALP PF00291.25 CDJ82417.1 - 2e-58 198.2 0.1 4e-39 134.8 0.0 2.0 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme Vault PF01505.18 CDJ82419.1 - 0.18 12.0 1.1 0.33 11.2 0.1 1.9 2 1 1 3 3 3 0 Major Vault Protein repeat domain TILa PF12714.7 CDJ82419.1 - 1.8 8.6 12.5 1.6 8.7 0.3 4.0 5 1 0 5 5 5 0 TILa domain MOLO1 PF17175.4 CDJ82420.1 - 4.9e-10 39.6 0.1 9.6e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 PsbJ PF01788.17 CDJ82420.1 - 0.1 12.5 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 PsbJ Ras PF00071.22 CDJ82421.1 - 6e-50 169.0 0.0 7.3e-50 168.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ82421.1 - 1e-27 96.7 0.0 1.5e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ82421.1 - 1.9e-13 50.3 0.0 2.6e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ82421.1 - 1e-06 28.8 0.0 1.5e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDJ82421.1 - 7.8e-06 25.4 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CDJ82421.1 - 0.098 12.6 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase MCM PF00493.23 CDJ82421.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_16 PF13191.6 CDJ82421.1 - 0.17 12.2 0.0 0.27 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain FYVE PF01363.21 CDJ82422.1 - 3.2e-15 56.0 9.1 4.4e-15 55.6 9.1 1.2 1 0 0 1 1 1 1 FYVE zinc finger UNC-79 PF14776.6 CDJ82422.1 - 0.024 13.4 2.2 0.024 13.4 2.2 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Cytochrome_CBB3 PF13442.6 CDJ82422.1 - 0.037 14.3 0.7 0.069 13.5 0.0 1.8 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Fer2_3 PF13085.6 CDJ82422.1 - 0.081 12.9 0.6 0.13 12.3 0.6 1.3 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF2757 PF10955.8 CDJ82422.1 - 0.35 11.2 0.3 0.35 11.2 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2757) FYVE_2 PF02318.16 CDJ82422.1 - 1.3 9.3 9.2 3 8.1 9.2 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger zf-B_box PF00643.24 CDJ82422.1 - 1.6 8.9 13.4 0.48 10.6 3.9 2.9 3 0 0 3 3 3 0 B-box zinc finger TPR_12 PF13424.6 CDJ82423.1 - 2.8e-16 59.5 14.2 1.3e-07 31.8 3.4 3.9 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_MalT PF17874.1 CDJ82423.1 - 1.2e-07 31.4 5.1 8.2e-05 22.1 0.4 2.8 1 1 2 3 3 3 2 MalT-like TPR region zf-RING_2 PF13639.6 CDJ82423.1 - 2.1e-06 28.0 5.5 2.1e-06 28.0 5.5 3.3 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 CDJ82423.1 - 6.5e-06 26.0 9.9 2.4e-05 24.2 9.9 2.1 1 0 0 1 1 1 1 zinc-RING finger domain TPR_2 PF07719.17 CDJ82423.1 - 3.4e-05 23.6 7.4 0.027 14.6 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ82423.1 - 7.3e-05 22.7 6.0 8.5 6.9 0.0 5.8 6 1 0 6 6 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ82423.1 - 8e-05 22.3 5.8 1.9 8.5 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat zf-C3HC4 PF00097.25 CDJ82423.1 - 0.00023 21.0 7.5 0.00024 20.9 5.2 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDJ82423.1 - 0.00026 21.2 3.7 0.00026 21.2 3.7 2.2 2 0 0 2 2 1 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 CDJ82423.1 - 0.0016 18.0 4.6 0.0054 16.3 4.6 1.9 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type TPR_10 PF13374.6 CDJ82423.1 - 0.0016 18.2 7.5 0.4 10.6 0.2 4.5 6 0 0 6 6 6 2 Tetratricopeptide repeat zf-RING_11 PF17123.5 CDJ82423.1 - 0.0017 18.1 1.4 0.0017 18.1 1.4 2.5 3 0 0 3 3 1 1 RING-like zinc finger TPR_7 PF13176.6 CDJ82423.1 - 0.0022 17.9 4.6 16 5.8 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.6 CDJ82423.1 - 0.0024 17.7 8.7 0.0024 17.7 8.7 3.0 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDJ82423.1 - 0.0049 16.9 2.3 0.012 15.6 2.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 CDJ82423.1 - 0.02 14.8 8.0 0.02 14.8 8.0 2.5 3 0 0 3 3 2 0 PHD-finger ANAPC5 PF12862.7 CDJ82423.1 - 0.056 13.5 9.2 0.11 12.6 0.3 3.8 3 2 1 4 4 4 0 Anaphase-promoting complex subunit 5 zf-RING-like PF08746.11 CDJ82423.1 - 0.17 12.2 10.4 0.068 13.5 5.8 2.6 2 0 0 2 2 2 0 RING-like domain zf-UDP PF14569.6 CDJ82423.1 - 0.54 10.4 5.3 0.31 11.2 2.4 2.1 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_UBOX PF13445.6 CDJ82423.1 - 0.95 9.5 8.5 0.66 10.0 5.7 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDJ82423.1 - 1.4 9.1 6.4 0.53 10.5 1.9 2.6 1 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 CDJ82423.1 - 5.1 7.2 10.5 0.75 9.9 4.3 2.8 2 1 0 2 2 2 0 Zinc-finger zf-RING_4 PF14570.6 CDJ82423.1 - 9.6 6.1 14.4 1.1 9.1 7.9 2.8 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Neur_chan_LBD PF02931.23 CDJ82424.1 - 1.3e-33 116.2 0.1 2e-33 115.7 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ82424.1 - 2.5e-18 67.0 0.4 1.1e-17 64.9 0.0 1.9 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Collagen PF01391.18 CDJ82426.1 - 1.8e-22 78.9 98.3 6.3e-09 35.5 30.8 4.7 3 1 1 4 4 4 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ82426.1 - 1.5e-06 28.1 0.1 2e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ82427.1 - 9.6e-23 79.7 87.5 1.1e-09 37.9 27.0 4.0 2 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ82427.1 - 2e-05 24.6 0.2 2.9e-05 24.0 0.2 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain GAS PF13851.6 CDJ82429.1 - 0.00083 18.8 38.7 0.0012 18.3 18.1 20.5 10 7 9 20 20 20 4 Growth-arrest specific micro-tubule binding Csm1_N PF18504.1 CDJ82429.1 - 0.0036 17.6 0.9 0.0036 17.6 0.9 29.2 20 11 14 34 34 34 4 Csm1 N-terminal domain dTDP_sugar_isom PF00908.17 CDJ82430.1 - 5.3e-32 110.8 0.0 5.7e-32 110.7 0.0 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase Rpr2 PF04032.16 CDJ82431.1 - 8.7e-09 35.6 0.5 1.5e-08 34.8 0.5 1.8 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Pox_E2-like PF04497.12 CDJ82431.1 - 0.031 12.8 0.0 0.036 12.5 0.0 1.0 1 0 0 1 1 1 0 Poxviridae protein Cys_rich_KTR PF14205.6 CDJ82431.1 - 0.81 9.5 4.9 0.34 10.7 1.4 2.1 2 0 0 2 2 2 0 Cysteine-rich KTR Dus PF01207.17 CDJ82432.1 - 1.2e-46 159.3 0.0 1.5e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Peptidase_M1 PF01433.20 CDJ82433.1 - 6.4e-07 29.2 0.0 1.1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain HEAT_2 PF13646.6 CDJ82433.1 - 7.7e-06 26.2 0.0 0.037 14.4 0.0 2.6 2 0 0 2 2 2 2 HEAT repeats Peptidase_M1_N PF17900.1 CDJ82433.1 - 0.001 19.3 0.0 0.002 18.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain BORCS6 PF10157.9 CDJ82434.1 - 5.4e-32 111.1 1.0 6.3e-32 110.9 1.0 1.1 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 zf-C2H2 PF00096.26 CDJ82435.1 - 7.6e-15 54.4 30.0 2.1e-06 27.9 2.2 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ82435.1 - 7.7e-15 54.6 29.8 9.1e-05 22.7 0.4 4.7 5 0 0 5 5 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDJ82435.1 - 1.3e-13 50.5 26.1 0.0014 19.3 1.2 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ82435.1 - 3.1e-08 33.7 8.0 0.043 14.1 0.2 3.5 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDJ82435.1 - 1.9e-05 24.9 20.5 0.0059 17.0 3.1 4.3 5 0 0 5 5 4 2 Zinc-finger of C2H2 type zf_UBZ PF18439.1 CDJ82435.1 - 5.3e-05 22.7 8.7 0.52 10.0 0.1 4.5 4 0 0 4 4 4 1 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 CDJ82435.1 - 5.8e-05 22.8 22.4 0.035 13.9 2.3 4.1 4 0 0 4 4 4 3 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 CDJ82435.1 - 0.00066 20.4 5.7 0.35 11.7 0.2 2.2 1 1 0 2 2 2 2 zinc-ribbon family zf-LYAR PF08790.11 CDJ82435.1 - 0.0016 18.3 3.4 13 5.8 0.0 3.4 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Elf1 PF05129.13 CDJ82435.1 - 0.0019 18.2 3.5 0.2 11.7 0.4 2.4 1 1 1 2 2 2 2 Transcription elongation factor Elf1 like C1_1 PF00130.22 CDJ82435.1 - 0.0025 17.6 5.2 0.2 11.5 0.6 2.6 1 1 1 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ribbon_3 PF13248.6 CDJ82435.1 - 0.0056 16.1 6.0 3.2 7.3 0.7 3.4 3 0 0 3 3 3 1 zinc-ribbon domain zf-C2H2_6 PF13912.6 CDJ82435.1 - 0.011 15.7 0.1 0.011 15.7 0.1 5.3 5 1 0 5 5 5 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 CDJ82435.1 - 0.013 15.6 10.5 0.02 15.0 1.0 3.2 2 2 1 3 3 3 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 CDJ82435.1 - 0.016 15.1 7.1 4.7 7.2 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon domain FOXP-CC PF16159.5 CDJ82435.1 - 0.016 15.8 2.4 0.028 15.0 1.1 1.9 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_2 PF12756.7 CDJ82435.1 - 0.02 15.2 13.4 0.71 10.2 5.2 3.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) CpXC PF14353.6 CDJ82435.1 - 0.028 14.5 7.3 0.23 11.5 1.0 3.1 1 1 2 3 3 3 0 CpXC protein ARS2 PF04959.13 CDJ82435.1 - 0.032 14.6 0.6 1.4 9.3 0.0 2.1 2 0 0 2 2 2 0 Arsenite-resistance protein 2 zf-C2H2_3rep PF18868.1 CDJ82435.1 - 0.032 14.9 8.1 1.4 9.6 2.9 3.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zinc-ribbons_6 PF07191.12 CDJ82435.1 - 0.055 13.5 9.2 0.3 11.1 2.1 3.0 1 1 1 2 2 2 0 zinc-ribbons zf-C2H2_8 PF15909.5 CDJ82435.1 - 0.13 12.5 11.3 0.045 14.1 4.8 2.2 1 1 1 2 2 2 0 C2H2-type zinc ribbon IBR PF01485.21 CDJ82435.1 - 0.15 12.3 13.4 3.9 7.8 3.1 2.8 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain LIM PF00412.22 CDJ82435.1 - 0.2 11.9 10.0 24 5.2 5.5 3.0 1 1 2 3 3 3 0 LIM domain PyrI_C PF02748.15 CDJ82435.1 - 0.24 11.4 4.8 2.3 8.2 0.5 2.9 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain TFIIS_C PF01096.18 CDJ82435.1 - 0.24 11.3 6.7 16 5.4 0.1 3.9 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) zf-HIT PF04438.16 CDJ82435.1 - 0.46 10.4 0.3 0.46 10.4 0.3 3.8 4 0 0 4 4 3 0 HIT zinc finger Nudix_N_2 PF14803.6 CDJ82435.1 - 0.53 10.2 10.6 14 5.7 0.3 3.9 3 1 1 4 4 4 0 Nudix N-terminal zinc_ribbon_9 PF14369.6 CDJ82435.1 - 0.74 10.1 7.7 12 6.3 0.0 3.9 4 0 0 4 4 4 0 zinc-ribbon DUF629 PF04780.12 CDJ82435.1 - 0.8 8.2 10.4 5.6 5.4 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF629) C1_4 PF07975.12 CDJ82435.1 - 0.92 9.8 12.2 0.19 12.0 0.9 3.1 1 1 2 3 3 3 0 TFIIH C1-like domain Sprouty PF05210.13 CDJ82435.1 - 1.3 9.5 8.6 0.31 11.5 5.3 1.8 2 1 0 2 2 1 0 Sprouty protein (Spry) ADK_lid PF05191.14 CDJ82435.1 - 1.4 9.0 10.5 0.095 12.7 1.2 2.8 3 1 0 3 3 2 0 Adenylate kinase, active site lid zf-nanos PF05741.13 CDJ82435.1 - 1.5 9.1 12.2 8.8 6.7 5.4 3.4 1 1 1 2 2 2 0 Nanos RNA binding domain Rubredoxin_2 PF18073.1 CDJ82435.1 - 2.6 7.9 11.2 9.5 6.1 0.8 3.4 3 0 0 3 3 3 0 Rubredoxin metal binding domain zf-H2C2_5 PF13909.6 CDJ82435.1 - 2.6 7.9 30.1 0.11 12.3 7.6 4.3 4 1 0 4 4 4 0 C2H2-type zinc-finger domain Desulfoferrod_N PF06397.12 CDJ82435.1 - 2.7 7.7 5.9 6.5 6.5 0.1 3.0 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain zf-AN1 PF01428.16 CDJ82435.1 - 3.2 8.0 18.6 1.8 8.8 3.0 4.3 3 2 0 3 3 3 0 AN1-like Zinc finger zf-CCHC_2 PF13696.6 CDJ82435.1 - 4.7 7.1 10.3 3 7.7 0.4 3.2 3 0 0 3 3 2 0 Zinc knuckle zf-C2HE PF16278.5 CDJ82435.1 - 6.6 7.3 16.3 2.3 8.7 3.0 3.7 1 1 3 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger Ribosomal_L37ae PF01780.19 CDJ82435.1 - 6.7 6.9 9.3 5.7 7.1 0.3 3.0 2 1 1 3 3 3 0 Ribosomal L37ae protein family FYDLN_acid PF09538.10 CDJ82435.1 - 8.3 7.1 6.8 29 5.4 0.9 3.3 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) Peptidase_M24 PF00557.24 CDJ82436.1 - 2.1e-55 187.7 1.7 1.1e-50 172.2 0.2 2.3 1 1 1 2 2 2 2 Metallopeptidase family M24 zf-C6H2 PF15801.5 CDJ82436.1 - 1.2e-18 67.1 8.3 2.8e-18 66.0 8.3 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 CDJ82436.1 - 5.6e-05 23.1 4.6 0.00017 21.6 4.6 1.9 1 0 0 1 1 1 1 MYND finger 3HCDH PF00725.22 CDJ82436.1 - 5.8e-05 23.6 0.2 7.7 7.2 0.0 3.4 3 0 0 3 3 3 3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ATP-cone PF03477.16 CDJ82436.1 - 0.0034 17.9 0.1 11 6.7 0.0 3.2 2 1 1 3 3 3 2 ATP cone domain ASC PF00858.24 CDJ82437.1 - 9e-20 71.1 0.5 1.2e-19 70.7 0.5 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel 4HBT_3 PF13622.6 CDJ82438.1 - 2.8e-53 181.7 1.5 3.3e-53 181.5 0.6 1.5 2 0 0 2 2 2 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 CDJ82438.1 - 3.4e-18 65.8 0.1 3.3e-13 49.6 0.0 2.9 2 1 0 2 2 2 2 Acyl-CoA thioesterase zf-H2C2_2 PF13465.6 CDJ82439.1 - 1.5e-05 25.2 4.0 1.5e-05 25.2 4.0 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 CDJ82439.1 - 0.0076 16.6 4.6 0.91 10.0 0.2 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CDJ82439.1 - 0.036 14.9 14.1 0.21 12.5 2.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CDJ82439.1 - 0.064 13.7 1.7 0.064 13.7 1.7 3.9 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 CDJ82439.1 - 0.26 11.6 8.8 0.46 10.8 5.2 2.9 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 CDJ82439.1 - 0.38 10.6 5.0 0.12 12.2 1.1 2.3 2 1 0 2 2 2 0 Rad50 zinc hook motif zf-BED PF02892.15 CDJ82439.1 - 0.45 10.6 6.8 3.1 7.9 6.8 2.2 1 1 0 1 1 1 0 BED zinc finger Homeodomain PF00046.29 CDJ82440.1 - 9.2e-11 41.4 0.1 1.6e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 Homeodomain ASF1_hist_chap PF04729.13 CDJ82441.1 - 7.2e-62 207.9 0.0 1e-61 207.4 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone DUF4407 PF14362.6 CDJ82441.1 - 5.2 6.3 7.7 7.3 5.8 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MADF_DNA_bdg PF10545.9 CDJ82442.1 - 1.1e-12 48.1 0.1 2e-12 47.2 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 CDJ82442.1 - 0.023 15.1 0.1 0.045 14.1 0.1 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Med26 PF08711.11 CDJ82443.1 - 3.4e-12 46.2 0.0 9.5e-12 44.8 0.0 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Acyl-CoA_ox_N PF14749.6 CDJ82443.1 - 0.064 13.8 0.1 0.25 11.9 0.1 2.0 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal PARM PF17061.5 CDJ82443.1 - 5.4 7.1 8.6 8.9 6.4 8.6 1.3 1 0 0 1 1 1 0 PARM CKS PF01111.19 CDJ82444.1 - 1.4e-36 124.5 1.6 1.7e-36 124.3 1.6 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit WD40 PF00400.32 CDJ82446.1 - 1.5e-16 60.4 11.5 4.4e-07 30.5 0.7 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ82446.1 - 2.6e-05 24.4 0.0 0.73 10.2 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDJ82446.1 - 0.052 12.2 0.1 1.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 STE PF02200.16 CDJ82446.1 - 0.17 12.4 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 STE like transcription factor PDCD2_C PF04194.13 CDJ82447.1 - 0.025 14.7 0.0 0.028 14.5 0.0 1.1 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain MULE PF10551.9 CDJ82448.1 - 1.1e-07 32.2 0.0 2.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain Circo_capsid PF02443.15 CDJ82448.1 - 8.5 5.9 11.2 13 5.3 11.2 1.2 1 0 0 1 1 1 0 Circovirus capsid protein FYVE PF01363.21 CDJ82449.1 - 6.6e-13 48.6 7.3 6.6e-13 48.6 7.3 1.9 2 0 0 2 2 2 1 FYVE zinc finger RhoGEF PF00621.20 CDJ82449.1 - 1.6e-07 31.7 6.4 5.5e-06 26.7 2.9 2.4 1 1 0 2 2 2 2 RhoGEF domain PH PF00169.29 CDJ82449.1 - 1.4e-05 25.5 0.1 0.029 14.9 0.1 2.7 2 0 0 2 2 2 2 PH domain PH_13 PF16652.5 CDJ82449.1 - 0.0043 16.9 0.2 0.069 13.0 0.1 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain FYVE_2 PF02318.16 CDJ82449.1 - 0.28 11.4 4.9 1.1 9.5 4.9 2.0 1 0 0 1 1 1 0 FYVE-type zinc finger IBR PF01485.21 CDJ82449.1 - 1.1 9.5 6.0 0.9 9.8 3.8 2.0 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zinc-ribbons_6 PF07191.12 CDJ82449.1 - 1.8 8.6 5.7 6.6 6.8 5.7 2.0 1 1 0 1 1 1 0 zinc-ribbons CUT PF02376.15 CDJ82451.1 - 3.1e-32 110.5 0.1 5e-32 109.9 0.1 1.3 1 0 0 1 1 1 1 CUT domain Homeodomain PF00046.29 CDJ82451.1 - 5.4e-11 42.2 0.4 1.2e-10 41.0 0.4 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ82451.1 - 0.0012 18.7 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain DZR PF12773.7 CDJ82452.1 - 0.081 13.0 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 CDJ82452.1 - 2.3 8.1 5.5 0.33 10.7 0.9 2.0 2 0 0 2 2 2 0 zinc-ribbon domain FragX_IP PF05994.11 CDJ82453.1 - 0 1128.3 3.6 0 1127.7 3.6 1.3 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 CDJ82453.1 - 1.4e-09 37.6 5.0 4.2e-09 36.1 5.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) Tnp_22_trimer PF17489.2 CDJ82453.1 - 0.096 12.7 0.1 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 L1 transposable element trimerization domain DUF3700 PF12481.8 CDJ82453.1 - 0.13 11.7 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Aluminium induced protein DNA_topoisoIV PF00521.20 CDJ82453.1 - 0.26 10.1 2.4 0.58 9.0 2.4 1.5 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Tho1_MOS11_C PF18592.1 CDJ82453.1 - 4.8 7.1 8.5 1 9.2 0.1 3.1 3 0 0 3 3 3 0 Tho1/MOS11 C-terminal domain KTI12 PF08433.10 CDJ82454.1 - 1e-83 280.9 0.1 1.3e-83 280.6 0.1 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 CDJ82454.1 - 7.2e-09 36.0 0.0 4.8e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CDJ82454.1 - 1.2e-05 24.7 0.1 0.0002 20.7 0.0 2.6 3 0 0 3 3 3 1 Zeta toxin APS_kinase PF01583.20 CDJ82454.1 - 0.00015 21.6 0.0 0.00025 21.0 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.6 CDJ82454.1 - 0.00043 20.7 0.0 0.0014 19.0 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 CDJ82454.1 - 0.00055 19.0 0.0 0.00097 18.2 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CDJ82454.1 - 0.0018 18.9 0.1 0.0095 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 CDJ82454.1 - 0.0037 17.1 0.1 0.0084 15.9 0.0 1.6 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein T2SSE PF00437.20 CDJ82454.1 - 0.0087 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 CDJ82454.1 - 0.0093 15.9 0.4 2.9 7.8 0.2 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_14 PF13173.6 CDJ82454.1 - 0.012 15.7 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CDJ82454.1 - 0.012 15.6 0.8 0.024 14.5 0.0 1.8 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.6 CDJ82454.1 - 0.027 14.2 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CDJ82454.1 - 0.028 14.7 0.0 0.12 12.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CDJ82454.1 - 0.029 14.4 0.0 0.072 13.2 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase DAP3 PF10236.9 CDJ82454.1 - 0.038 13.2 0.0 0.065 12.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 RNA_helicase PF00910.22 CDJ82454.1 - 0.11 13.0 0.0 0.31 11.4 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 CDJ82454.1 - 0.12 12.8 0.0 0.63 10.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain P5CR_dimer PF14748.6 CDJ82455.1 - 3e-37 127.0 0.8 5.9e-37 126.1 0.8 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CDJ82455.1 - 4.8e-05 23.9 0.0 0.00011 22.7 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Ribosomal_S11 PF00411.19 CDJ82455.1 - 0.13 12.7 0.1 0.26 11.7 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S11 DDE_Tnp_4 PF13359.6 CDJ82456.1 - 1e-20 74.0 0.0 1.2e-20 73.7 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 CDJ82456.1 - 0.0004 20.1 0.0 0.00068 19.3 0.0 1.3 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 CDJ82456.1 - 0.02 15.3 0.0 0.031 14.6 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_1 PF01609.21 CDJ82456.1 - 0.17 11.5 0.2 1.2 8.8 0.2 2.1 1 1 0 1 1 1 0 Transposase DDE domain YEATS PF03366.16 CDJ82457.1 - 4.6e-17 61.8 0.2 8.4e-17 60.9 0.2 1.3 1 0 0 1 1 1 1 YEATS family AHD PF17793.1 CDJ82457.1 - 0.00046 19.9 0.0 0.00099 18.9 0.0 1.5 1 0 0 1 1 1 1 ANC1 homology domain (AHD) BUD22 PF09073.10 CDJ82457.1 - 0.0053 16.1 16.9 0.0071 15.7 16.9 1.1 1 0 0 1 1 1 1 BUD22 Macoilin PF09726.9 CDJ82457.1 - 0.032 12.8 9.3 0.038 12.6 9.3 1.1 1 0 0 1 1 1 0 Macoilin family Zip PF02535.22 CDJ82457.1 - 0.18 11.0 3.7 0.22 10.7 3.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4887 PF16228.5 CDJ82457.1 - 0.87 9.7 19.0 0.025 14.8 9.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4887) NPR3 PF03666.13 CDJ82457.1 - 0.89 8.3 11.5 1.1 8.0 11.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RPN2_C PF18004.1 CDJ82457.1 - 0.91 9.4 11.7 1.6 8.6 11.7 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RR_TM4-6 PF06459.12 CDJ82457.1 - 1.8 8.3 9.3 2.6 7.8 9.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SRP-alpha_N PF04086.13 CDJ82457.1 - 2.5 7.9 17.1 3.4 7.5 17.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDC45 PF02724.14 CDJ82457.1 - 3.3 5.9 12.0 4 5.6 12.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CDJ82457.1 - 4.4 6.0 9.0 5.8 5.6 9.0 1.2 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 CDJ82457.1 - 6.4 3.8 8.9 7 3.6 8.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peptidase_S64 PF08192.11 CDJ82457.1 - 9.6 4.5 9.7 13 4.2 9.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 Pentapeptide PF00805.22 CDJ82458.1 - 0.074 12.7 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) DUF4250 PF14056.6 CDJ82458.1 - 5.8 6.9 10.9 9.8 6.2 0.9 4.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4250) HhH-GPD PF00730.25 CDJ82459.1 - 1.1e-19 70.9 0.0 4.8e-19 68.8 0.0 2.0 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CDJ82459.1 - 9e-10 37.9 0.0 3.5e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_8 PF14716.6 CDJ82459.1 - 0.085 13.2 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain N36 PF11438.8 CDJ82459.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 36-mer N-terminal peptide of the N protein (N36) VWA PF00092.28 CDJ82460.1 - 3.2e-16 60.1 3.0 4.6e-12 46.5 0.1 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain Lectin_C PF00059.21 CDJ82460.1 - 3.4e-14 53.5 0.4 3.4e-14 53.5 0.4 2.3 2 1 1 3 3 3 1 Lectin C-type domain VWA_2 PF13519.6 CDJ82460.1 - 2.5e-08 34.5 0.3 0.0011 19.6 0.1 3.1 3 1 0 3 3 3 2 von Willebrand factor type A domain 7TM_GPCR_Srx PF10328.9 CDJ82462.1 - 8.9e-13 48.5 0.1 1e-12 48.3 0.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx TPR_12 PF13424.6 CDJ82463.1 - 6.2e-15 55.3 2.2 3.6e-07 30.4 0.1 3.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ82463.1 - 2.3e-06 27.2 9.9 0.0033 17.2 0.2 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ82463.1 - 4.2e-06 26.5 9.1 0.0047 16.9 0.3 3.2 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ82463.1 - 0.00032 20.5 0.2 0.51 10.3 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ82463.1 - 0.00072 19.6 10.2 0.23 11.7 0.8 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat DUF3856 PF12968.7 CDJ82463.1 - 0.00082 19.5 0.1 0.12 12.4 0.0 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_7 PF13176.6 CDJ82463.1 - 0.0032 17.4 1.2 0.084 12.9 0.1 3.7 5 0 0 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ82463.1 - 0.0068 16.6 9.3 0.67 10.2 0.4 3.6 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CDJ82463.1 - 0.0075 16.8 2.9 1.9 9.3 0.2 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ82463.1 - 0.012 15.2 5.7 0.68 9.7 0.7 2.6 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.6 CDJ82463.1 - 0.013 16.3 0.1 1.3 10.0 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat SPO22 PF08631.10 CDJ82463.1 - 0.03 13.8 3.6 0.029 13.9 1.2 2.0 2 1 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_16 PF13432.6 CDJ82463.1 - 0.055 14.1 0.1 5.2 7.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Ldh_1_N PF00056.23 CDJ82464.1 - 2e-16 60.4 0.0 2.7e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain AIM3 PF17096.5 CDJ82465.1 - 0.54 11.2 4.0 0.98 10.4 4.0 1.4 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 PBP1_TM PF14812.6 CDJ82465.1 - 1.5 9.2 5.3 2.6 8.5 5.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hint PF01079.20 CDJ82466.1 - 5.9e-40 137.1 0.1 8.9e-40 136.5 0.1 1.2 1 0 0 1 1 1 1 Hint module Hint_2 PF13403.6 CDJ82466.1 - 1.5e-05 25.3 0.1 0.00018 21.8 0.1 2.6 2 1 0 2 2 2 1 Hint domain Intein_splicing PF14890.6 CDJ82466.1 - 0.0027 17.7 0.1 0.1 12.5 0.1 2.5 2 1 1 3 3 3 1 Intein splicing domain PHO4 PF01384.20 CDJ82467.1 - 3e-128 427.6 14.9 5.1e-128 426.8 14.9 1.4 1 0 0 1 1 1 1 Phosphate transporter family DUF742 PF05331.11 CDJ82467.1 - 0.019 14.8 0.0 0.21 11.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF742) DUF3995 PF13160.6 CDJ82467.1 - 0.02 15.2 0.5 0.02 15.2 0.5 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF3995) HTH_IclR PF09339.10 CDJ82467.1 - 0.024 14.4 0.4 0.9 9.4 0.1 2.4 2 0 0 2 2 2 0 IclR helix-turn-helix domain DUF4396 PF14342.6 CDJ82467.1 - 0.93 9.8 15.5 2.1 8.7 4.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4396) Exo_endo_phos_2 PF14529.6 CDJ82468.1 - 7.3e-05 22.6 0.0 0.00017 21.4 0.0 1.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ82468.1 - 0.00047 19.8 0.0 0.0011 18.5 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MscS_porin PF12795.7 CDJ82469.1 - 0.0047 16.5 0.5 0.0047 16.5 0.5 2.0 2 1 0 2 2 2 1 Mechanosensitive ion channel porin domain DUF2730 PF10805.8 CDJ82469.1 - 0.2 11.8 2.1 0.43 10.7 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) DUF1664 PF07889.12 CDJ82469.1 - 0.29 11.2 6.9 0.23 11.5 3.1 2.5 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) ApoLp-III PF07464.11 CDJ82469.1 - 0.34 11.0 5.4 1.1 9.3 1.4 2.8 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) BLOC1_2 PF10046.9 CDJ82469.1 - 0.76 10.1 4.8 8.1 6.8 2.9 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF19 PF01579.18 CDJ82469.1 - 0.87 9.4 7.9 2.9 7.7 0.9 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF19) Arm-DNA-bind_5 PF17293.2 CDJ82469.1 - 2.8 8.5 6.2 0.31 11.5 0.4 2.4 2 2 0 2 2 2 0 Arm DNA-binding domain ERM PF00769.19 CDJ82469.1 - 8.3 6.1 13.4 0.27 11.0 4.4 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF5082 PF16888.5 CDJ82469.1 - 8.5 6.7 14.0 0.18 12.1 1.7 3.5 3 1 0 4 4 4 0 Domain of unknown function (DUF5082) Neur_chan_LBD PF02931.23 CDJ82470.1 - 7.9e-44 149.7 1.7 1.2e-43 149.1 1.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ82470.1 - 7.2e-29 101.5 6.9 1.8e-26 93.7 1.6 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Mito_fiss_reg PF05308.11 CDJ82473.1 - 2.5 8.1 9.0 2.5 8.1 9.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator NUDIX PF00293.28 CDJ82474.1 - 2.2e-10 40.7 0.0 3e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Nudix_hydro PF18290.1 CDJ82474.1 - 5.6e-05 23.1 0.7 0.00039 20.4 0.2 2.2 2 0 0 2 2 2 1 Nudix hydrolase domain NUDIX PF00293.28 CDJ82476.1 - 7.7e-14 51.9 0.1 1.3e-13 51.2 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain Nudix_hydro PF18290.1 CDJ82476.1 - 7.9e-05 22.6 0.2 0.00015 21.7 0.2 1.4 1 0 0 1 1 1 1 Nudix hydrolase domain DUF3108 PF11306.8 CDJ82476.1 - 0.017 15.1 0.1 4.4 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3108) Nudix_hydro PF18290.1 CDJ82477.1 - 3.1e-18 65.6 0.1 7e-18 64.4 0.1 1.6 1 0 0 1 1 1 1 Nudix hydrolase domain NUDIX PF00293.28 CDJ82477.1 - 6.3e-15 55.4 0.0 1.4e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Peptidase_M13_N PF05649.13 CDJ82479.1 - 1.8e-60 205.7 0.1 1.8e-60 205.7 0.1 1.8 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.21 CDJ82479.1 - 1.1e-30 106.8 0.0 2.4e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M13 GDE_C PF06202.14 CDJ82479.1 - 0.039 12.9 0.1 2.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Amylo-alpha-1,6-glucosidase Nudc_N PF14050.6 CDJ82479.1 - 0.15 12.1 0.1 0.87 9.6 0.1 2.2 2 0 0 2 2 2 0 N-terminal conserved domain of Nudc. Peptidase_S64 PF08192.11 CDJ82480.1 - 0.0045 15.5 0.0 0.0066 15.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S64 DUF1043 PF06295.12 CDJ82480.1 - 0.078 13.0 0.2 10 6.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Zf_RING PF16744.5 CDJ82481.1 - 0.1 12.7 0.8 0.1 12.7 0.8 2.2 1 1 0 2 2 2 0 KIAA1045 RING finger GlutR_dimer PF00745.20 CDJ82481.1 - 0.12 12.9 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain PTPLA PF04387.14 CDJ82482.1 - 5.8e-49 166.0 11.0 6.5e-49 165.8 11.0 1.0 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Ion_trans_2 PF07885.16 CDJ82483.1 - 2.8e-05 24.0 10.1 0.00043 20.2 0.2 3.6 3 1 0 3 3 3 2 Ion channel zf-C2H2 PF00096.26 CDJ82485.1 - 4.1e-08 33.3 16.4 4.4e-05 23.7 5.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ82485.1 - 9.6e-07 29.1 12.9 0.00011 22.8 3.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDJ82485.1 - 4.4e-05 23.7 4.1 4.4e-05 23.7 4.1 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 CDJ82485.1 - 0.00012 22.0 2.7 0.00012 22.0 2.7 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ82485.1 - 0.027 14.8 8.2 0.029 14.6 0.7 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-CHCC PF10276.9 CDJ82485.1 - 0.034 14.2 0.2 0.091 12.8 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger domain zf-Di19 PF05605.12 CDJ82485.1 - 0.094 13.0 0.4 0.094 13.0 0.4 1.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CDJ82485.1 - 4.1 7.9 5.6 33 5.0 1.1 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 CDJ82485.1 - 6.3 6.8 6.8 0.59 10.1 1.3 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type HTH_48 PF17906.1 CDJ82486.1 - 1.3e-20 73.2 1.1 1.6e-20 73.0 1.1 1.1 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_28 PF13518.6 CDJ82486.1 - 0.024 14.7 0.0 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_32 PF13565.6 CDJ82486.1 - 0.028 15.0 0.0 0.039 14.6 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain DUF4817 PF16087.5 CDJ82486.1 - 0.073 12.9 0.9 0.11 12.3 0.9 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) HTH_23 PF13384.6 CDJ82486.1 - 0.13 12.1 0.0 0.4 10.5 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain Caprin-1_dimer PF18293.1 CDJ82487.1 - 1.2e-06 29.0 0.0 2.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Caprin-1 dimerization domain RUN PF02759.19 CDJ82488.1 - 2.8e-24 85.6 1.1 5.6e-24 84.6 0.2 2.0 2 0 0 2 2 2 1 RUN domain BORCS8 PF10167.9 CDJ82488.1 - 0.044 13.7 1.1 0.19 11.7 0.1 2.3 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 TSC22 PF01166.18 CDJ82488.1 - 0.12 12.7 7.2 0.14 12.5 0.0 3.5 3 1 0 3 3 3 0 TSC-22/dip/bun family Pox_A_type_inc PF04508.12 CDJ82488.1 - 0.19 11.7 4.8 11 6.1 1.5 3.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF3323 PF11796.8 CDJ82488.1 - 0.29 11.0 3.0 0.82 9.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) DUF745 PF05335.13 CDJ82488.1 - 1.4 8.6 15.7 1.2 8.8 0.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF745) BLOC1_2 PF10046.9 CDJ82488.1 - 7.5 6.9 20.4 16 5.9 3.7 3.5 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Vps39_2 PF10367.9 CDJ82489.1 - 2.4e-11 44.0 3.7 6.5e-11 42.7 3.7 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 CDJ82489.1 - 9.9e-10 38.5 0.6 2.3e-09 37.2 0.6 1.6 1 0 0 1 1 1 1 CNH domain Myb_CC_LHEQLE PF14379.6 CDJ82491.1 - 0.004 16.8 0.6 0.0061 16.2 0.6 1.2 1 0 0 1 1 1 1 MYB-CC type transfactor, LHEQLE motif Glyco_transf_28 PF03033.20 CDJ82492.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Filament PF00038.21 CDJ82493.1 - 4e-43 148.2 36.2 4e-43 148.2 36.2 3.8 3 1 1 4 4 4 1 Intermediate filament protein Filament PF00038.21 CDJ82494.1 - 8.6e-13 48.5 22.9 1.2e-12 48.0 22.9 1.2 1 0 0 1 1 1 1 Intermediate filament protein DUF1878 PF08963.10 CDJ82494.1 - 0.14 12.7 2.5 0.75 10.3 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1878) zf-CpG_bind_C PF12269.8 CDJ82494.1 - 0.42 10.4 7.0 0.091 12.5 2.3 2.1 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain FTA4 PF13093.6 CDJ82494.1 - 2.1 8.2 17.8 0.88 9.4 7.3 2.4 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 RA PF00788.23 CDJ82495.1 - 7.9e-06 26.4 0.8 1.3e-05 25.8 0.0 1.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain AAA_23 PF13476.6 CDJ82495.1 - 0.032 14.7 3.0 0.056 13.9 3.0 1.3 1 0 0 1 1 1 0 AAA domain GAS PF13851.6 CDJ82495.1 - 0.14 11.5 9.9 0.26 10.6 9.9 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CRR7 PF12095.8 CDJ82495.1 - 7 7.2 7.3 12 6.5 1.3 3.2 2 1 1 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 Exonuc_VII_L PF02601.15 CDJ82495.1 - 8.7 5.8 8.0 4.8 6.7 5.9 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit TIL PF01826.17 CDJ82496.1 - 1e-09 38.5 16.5 1.3e-09 38.1 16.5 1.1 1 0 0 1 1 1 1 Trypsin Inhibitor like cysteine rich domain FeoB_associated PF12669.7 CDJ82496.1 - 3.9 8.0 11.5 16 6.0 11.5 2.1 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein TMEM135_C_rich PF15982.5 CDJ82497.1 - 5.2e-28 98.3 1.0 5.2e-28 98.3 1.0 1.9 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 CDJ82497.1 - 0.00014 22.2 0.1 0.00069 20.0 0.0 2.2 2 1 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Rnf-Nqr PF02508.14 CDJ82497.1 - 0.0076 16.2 2.6 0.66 9.9 0.0 2.5 2 0 0 2 2 2 2 Rnf-Nqr subunit, membrane protein MAPEG PF01124.18 CDJ82497.1 - 0.021 14.7 2.8 0.57 10.1 0.7 2.6 2 0 0 2 2 2 0 MAPEG family DUF1732 PF08340.11 CDJ82498.1 - 0.027 14.4 1.2 0.26 11.3 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1732) DUF3053 PF11254.8 CDJ82498.1 - 0.046 13.3 0.1 0.072 12.7 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3053) T2SSF PF00482.23 CDJ82498.1 - 0.15 12.0 0.2 0.58 10.1 0.0 2.1 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F Insulin PF00049.18 CDJ82499.1 - 1.7e-07 32.2 7.2 2.2e-06 28.6 7.2 2.0 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.14 CDJ82499.1 - 8.6e-05 22.5 10.6 0.0034 17.4 3.3 2.3 2 0 0 2 2 2 2 Nematode insulin-related peptide beta type Homeodomain PF00046.29 CDJ82501.1 - 9.1e-21 73.5 3.9 1.4e-20 72.8 3.9 1.3 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 CDJ82501.1 - 0.0022 17.4 0.3 0.0055 16.2 0.3 1.7 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 CDJ82501.1 - 0.003 17.4 0.1 0.0066 16.3 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain DNApol_Exo PF18136.1 CDJ82501.1 - 0.07 12.2 0.5 0.099 11.8 0.5 1.2 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain YdaS_antitoxin PF15943.5 CDJ82501.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Annexin PF00191.20 CDJ82502.1 - 1.5e-82 271.6 9.6 6.2e-23 80.7 0.1 4.1 4 0 0 4 4 4 4 Annexin DUF2312 PF10073.9 CDJ82502.1 - 0.016 14.8 0.0 0.071 12.8 0.0 2.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) UBA_2 PF08587.11 CDJ82502.1 - 0.033 14.3 0.3 1.3 9.2 0.0 3.3 3 0 0 3 3 3 0 Ubiquitin associated domain (UBA) RVT_1 PF00078.27 CDJ82503.1 - 3.5e-09 36.5 0.0 5.4e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cu2_monoox_C PF03712.15 CDJ82505.1 - 3.9e-29 101.2 0.0 9.3e-29 100.0 0.0 1.6 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain NHL PF01436.21 CDJ82505.1 - 8.9e-21 72.8 0.4 3.8e-06 26.7 0.0 4.6 4 0 0 4 4 4 4 NHL repeat Cu2_monooxygen PF01082.20 CDJ82505.1 - 6.7e-18 65.2 0.0 2.5e-17 63.3 0.0 1.9 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Lactonase PF10282.9 CDJ82505.1 - 0.038 13.3 0.0 0.86 8.8 0.0 2.2 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller AAA_29 PF13555.6 CDJ82505.1 - 0.051 13.3 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain SNRNP27 PF08648.12 CDJ82506.1 - 5e-19 68.1 1.4 1.2e-18 66.9 1.4 1.7 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Sec5 PF15469.6 CDJ82507.1 - 6.7e-41 140.2 5.1 1.6e-40 138.9 5.1 1.7 1 0 0 1 1 1 1 Exocyst complex component Sec5 Tmemb_170 PF10190.9 CDJ82507.1 - 3.6e-20 72.3 7.8 1.2e-19 70.6 7.8 1.9 1 0 0 1 1 1 1 Putative transmembrane protein 170 Metallophos PF00149.28 CDJ82507.1 - 2.3e-11 44.6 0.2 4.8e-11 43.5 0.2 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TIG PF01833.24 CDJ82507.1 - 1.7e-08 34.4 0.0 4.4e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 IPT/TIG domain Metallophos_2 PF12850.7 CDJ82507.1 - 1.3e-06 28.7 0.1 3.5e-06 27.3 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 CDJ82508.1 - 4.9e-11 43.5 0.9 1.2e-10 42.2 0.9 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDJ82508.1 - 8.9e-09 35.8 0.0 2.1e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Cation_ATPase_C PF00689.21 CDJ82508.1 - 0.23 11.2 5.4 0.57 9.9 5.4 1.7 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus G-patch PF01585.23 CDJ82509.1 - 1.9e-12 46.9 0.9 3.4e-12 46.0 0.9 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CDJ82509.1 - 0.00055 20.0 0.6 0.00055 20.0 0.6 3.4 3 1 0 3 3 3 1 G-patch domain DUF4366 PF14283.6 CDJ82509.1 - 0.019 15.0 2.5 0.03 14.4 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Arena_glycoprot PF00798.18 CDJ82509.1 - 0.18 10.4 0.1 0.24 10.0 0.1 1.1 1 0 0 1 1 1 0 Arenavirus glycoprotein SNARE PF05739.19 CDJ82510.1 - 1e-16 60.6 0.5 1e-16 60.6 0.5 3.3 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.6 CDJ82510.1 - 6.5e-15 55.3 11.7 6.5e-15 55.3 11.7 2.6 2 1 1 3 3 3 1 Syntaxin-like protein Syntaxin PF00804.25 CDJ82510.1 - 7.7e-05 22.5 27.1 0.008 15.9 27.1 3.0 1 1 0 1 1 1 1 Syntaxin APG6_N PF17675.1 CDJ82510.1 - 0.0012 19.4 11.6 0.0012 19.4 11.6 2.7 1 1 1 3 3 3 1 Apg6 coiled-coil region Baculo_F PF12259.8 CDJ82510.1 - 0.0019 16.8 5.4 0.0077 14.8 1.4 2.1 2 0 0 2 2 2 1 Baculovirus F protein BLOC1_2 PF10046.9 CDJ82510.1 - 0.0068 16.7 0.5 0.0068 16.7 0.5 3.9 1 1 2 4 4 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Dam1 PF08653.10 CDJ82510.1 - 0.068 13.0 13.2 1.4 8.8 1.4 3.6 2 1 1 3 3 3 0 DASH complex subunit Dam1 DUF4988 PF16378.5 CDJ82510.1 - 0.085 12.5 6.8 0.29 10.8 0.6 2.4 2 1 0 2 2 2 0 Domain of unknown function MbeD_MobD PF04899.12 CDJ82510.1 - 0.13 12.4 0.0 0.13 12.4 0.0 3.8 2 1 2 4 4 3 0 MbeD/MobD like DUF1676 PF07898.13 CDJ82510.1 - 0.7 9.9 9.4 0.089 12.8 5.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1676) YabA PF06156.13 CDJ82510.1 - 1.5 9.5 22.6 59 4.4 0.6 3.6 1 1 1 2 2 2 0 Initiation control protein YabA KIP1 PF07765.12 CDJ82510.1 - 1.6 8.9 8.9 1.9 8.6 2.0 3.2 2 2 1 3 3 3 0 KIP1-like protein NPV_P10 PF05531.12 CDJ82510.1 - 2.3 8.7 9.1 2.8 8.5 1.1 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 CDJ82510.1 - 2.5 8.6 24.5 2.4 8.7 6.3 3.1 1 1 2 3 3 3 0 Protein of unknown function DUF16 DUF3573 PF12097.8 CDJ82510.1 - 5.3 5.8 12.5 0.059 12.2 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) PCRF PF03462.18 CDJ82510.1 - 6.1 6.7 21.0 6.3 6.6 5.0 2.2 1 1 0 2 2 2 0 PCRF domain FapA PF03961.13 CDJ82510.1 - 6.4 5.3 22.6 0.2 10.2 7.7 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A FlaC_arch PF05377.11 CDJ82510.1 - 8 6.9 8.9 14 6.1 2.0 3.5 2 2 3 5 5 5 0 Flagella accessory protein C (FlaC) FUSC PF04632.12 CDJ82510.1 - 10 4.5 21.3 25 3.2 21.4 1.6 1 1 0 1 1 1 0 Fusaric acid resistance protein family NIF PF03031.18 CDJ82511.1 - 1.5e-23 83.3 0.1 3.2e-23 82.2 0.1 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 CDJ82511.1 - 2.9e-10 40.4 0.0 6.5e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CDJ82511.1 - 1.9e-08 34.1 0.2 6.4e-08 32.4 0.1 2.0 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 CDJ82511.1 - 0.0047 17.2 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain DWNN PF08783.11 CDJ82512.1 - 7.5e-21 74.2 0.0 1.9e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 CDJ82512.1 - 3.4e-08 33.1 9.1 6.3e-08 32.3 9.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 CDJ82512.1 - 1.8e-05 24.5 7.7 1.8e-05 24.5 7.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ82512.1 - 0.026 14.7 9.9 0.051 13.7 9.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CDJ82512.1 - 0.08 13.3 9.2 0.18 12.2 9.2 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 CDJ82512.1 - 0.19 11.8 7.9 0.48 10.5 7.9 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-CCHC PF00098.23 CDJ82512.1 - 0.31 11.2 3.7 0.76 10.0 3.7 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-RING_5 PF14634.6 CDJ82512.1 - 0.36 10.8 15.8 0.057 13.4 9.6 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_6 PF14835.6 CDJ82512.1 - 0.54 10.2 4.3 1.2 9.0 4.3 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 CDJ82512.1 - 2.6 8.0 15.3 0.019 14.9 7.0 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Costars PF14705.6 CDJ82513.1 - 1e-31 108.9 0.4 2.1e-31 107.9 0.4 1.5 1 0 0 1 1 1 1 Costars Filament PF00038.21 CDJ82514.1 - 2.3e-24 86.5 17.8 3.1e-24 86.1 17.8 1.1 1 0 0 1 1 1 1 Intermediate filament protein DUF4407 PF14362.6 CDJ82514.1 - 3.1e-05 23.5 9.4 0.0002 20.8 9.8 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) DUF1664 PF07889.12 CDJ82514.1 - 0.00019 21.4 7.3 0.0015 18.6 4.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) APG6_N PF17675.1 CDJ82514.1 - 0.00036 21.1 21.8 0.27 11.8 15.1 3.0 1 1 2 3 3 3 3 Apg6 coiled-coil region Prefoldin_2 PF01920.20 CDJ82514.1 - 0.00041 20.3 16.4 0.018 15.0 2.5 3.2 3 0 0 3 3 3 2 Prefoldin subunit Taxilin PF09728.9 CDJ82514.1 - 0.00048 19.4 17.2 0.06 12.5 8.1 2.1 1 1 1 2 2 2 2 Myosin-like coiled-coil protein CENP-H PF05837.12 CDJ82514.1 - 0.00072 19.9 14.9 0.063 13.7 3.0 3.1 1 1 2 3 3 3 1 Centromere protein H (CENP-H) TPR_MLP1_2 PF07926.12 CDJ82514.1 - 0.00082 19.4 12.6 0.21 11.6 9.4 2.6 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein Lzipper-MIP1 PF14389.6 CDJ82514.1 - 0.00084 19.6 8.5 0.00084 19.6 8.5 2.1 2 0 0 2 2 1 1 Leucine-zipper of ternary complex factor MIP1 ATG16 PF08614.11 CDJ82514.1 - 0.0011 19.2 13.3 0.002 18.4 13.3 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Uso1_p115_C PF04871.13 CDJ82514.1 - 0.0012 19.2 11.0 0.0012 19.2 11.0 2.6 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region SOGA PF11365.8 CDJ82514.1 - 0.0013 19.8 15.3 0.032 15.3 6.4 3.5 1 1 2 3 3 3 1 Protein SOGA DivIC PF04977.15 CDJ82514.1 - 0.0013 18.4 17.6 0.14 11.9 1.7 3.5 1 1 1 3 3 3 2 Septum formation initiator HR1 PF02185.16 CDJ82514.1 - 0.002 18.2 13.6 0.042 14.0 0.8 3.3 3 0 0 3 3 3 2 Hr1 repeat CCD48 PF15799.5 CDJ82514.1 - 0.0022 16.4 9.3 0.0051 15.2 9.3 1.5 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 48 GAS PF13851.6 CDJ82514.1 - 0.0029 17.0 20.4 0.027 13.8 9.2 2.2 1 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding HALZ PF02183.18 CDJ82514.1 - 0.0029 17.8 10.7 0.1 12.8 0.5 3.6 3 1 1 4 4 3 1 Homeobox associated leucine zipper ERM PF00769.19 CDJ82514.1 - 0.0032 17.3 11.2 0.0032 17.3 11.2 2.2 1 1 1 2 2 2 2 Ezrin/radixin/moesin family YabA PF06156.13 CDJ82514.1 - 0.0037 17.9 15.8 0.3 11.7 3.2 3.1 1 1 1 2 2 2 1 Initiation control protein YabA Snapin_Pallidin PF14712.6 CDJ82514.1 - 0.0043 17.4 9.1 0.012 16.1 5.3 2.7 2 1 0 2 2 2 1 Snapin/Pallidin CCDC-167 PF15188.6 CDJ82514.1 - 0.0045 17.3 16.1 0.13 12.6 11.7 2.8 2 1 1 3 3 3 1 Coiled-coil domain-containing protein 167 DUF5082 PF16888.5 CDJ82514.1 - 0.0045 17.3 12.5 0.22 11.8 0.5 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF5082) Myosin_tail_1 PF01576.19 CDJ82514.1 - 0.0049 14.8 18.4 0.0076 14.1 18.3 1.3 1 1 0 1 1 1 1 Myosin tail FlaC_arch PF05377.11 CDJ82514.1 - 0.0062 16.9 12.8 1.1 9.8 3.9 3.7 2 1 0 3 3 3 1 Flagella accessory protein C (FlaC) SlyX PF04102.12 CDJ82514.1 - 0.0062 17.1 13.5 1.8 9.2 0.2 3.2 3 0 0 3 3 3 0 SlyX ADIP PF11559.8 CDJ82514.1 - 0.007 16.5 16.9 1.4 9.0 4.7 3.1 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding OmpH PF03938.14 CDJ82514.1 - 0.0076 16.6 11.7 0.1 13.0 9.3 2.3 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) Bacillus_HBL PF05791.11 CDJ82514.1 - 0.01 15.7 5.3 0.018 14.8 1.3 2.4 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) UPF0242 PF06785.11 CDJ82514.1 - 0.011 15.9 16.0 0.17 11.9 4.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Laminin_II PF06009.12 CDJ82514.1 - 0.011 15.7 11.7 0.15 12.1 7.3 2.3 2 0 0 2 2 2 0 Laminin Domain II CtIP_N PF10482.9 CDJ82514.1 - 0.015 15.3 15.2 0.068 13.2 4.1 3.0 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain TMF_TATA_bd PF12325.8 CDJ82514.1 - 0.018 15.3 20.4 0.031 14.5 2.5 3.2 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Apolipoprotein PF01442.18 CDJ82514.1 - 0.019 14.9 13.3 0.23 11.3 13.3 2.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4600 PF15372.6 CDJ82514.1 - 0.021 15.3 5.6 0.021 15.3 5.6 2.5 1 1 2 3 3 2 0 Domain of unknown function (DUF4600) Lebercilin PF15619.6 CDJ82514.1 - 0.024 14.3 17.6 0.094 12.4 16.9 2.1 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 CDJ82514.1 - 0.029 13.3 17.7 0.063 12.1 12.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DegS PF05384.11 CDJ82514.1 - 0.03 13.8 17.3 0.76 9.2 11.0 2.2 1 1 1 2 2 2 0 Sensor protein DegS DHR10 PF18595.1 CDJ82514.1 - 0.031 14.3 20.3 0.098 12.7 10.7 3.0 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain DUF16 PF01519.16 CDJ82514.1 - 0.031 14.8 8.8 1.3 9.5 4.8 2.8 1 1 2 3 3 3 0 Protein of unknown function DUF16 Fez1 PF06818.15 CDJ82514.1 - 0.041 14.3 15.3 0.065 13.7 8.1 2.1 1 1 1 2 2 2 0 Fez1 GrpE PF01025.19 CDJ82514.1 - 0.047 13.4 18.2 0.87 9.2 1.0 3.1 1 1 2 3 3 3 0 GrpE THOC7 PF05615.13 CDJ82514.1 - 0.052 13.8 21.2 3.7 7.8 2.5 3.2 1 1 1 2 2 2 0 Tho complex subunit 7 Seryl_tRNA_N PF02403.22 CDJ82514.1 - 0.052 13.8 17.4 0.1 12.8 6.3 2.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain COG2 PF06148.11 CDJ82514.1 - 0.054 13.6 5.5 0.16 12.1 3.5 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Ax_dynein_light PF10211.9 CDJ82514.1 - 0.064 13.2 16.5 0.099 12.6 11.4 2.7 1 1 1 2 2 2 0 Axonemal dynein light chain DUF4201 PF13870.6 CDJ82514.1 - 0.064 13.0 22.1 0.29 10.9 4.3 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) ZapB PF06005.12 CDJ82514.1 - 0.064 13.7 20.6 0.48 10.9 6.7 3.3 1 1 1 2 2 2 0 Cell division protein ZapB TMF_DNA_bd PF12329.8 CDJ82514.1 - 0.067 13.2 22.1 0.13 12.3 5.6 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 CDJ82514.1 - 0.075 13.1 21.0 1.7 8.7 5.3 3.0 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4618 PF15397.6 CDJ82514.1 - 0.076 12.4 14.9 3.8 6.9 15.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) IFP_35_N PF07334.13 CDJ82514.1 - 0.076 13.1 10.7 0.42 10.7 1.3 3.0 2 1 1 3 3 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Prominin PF05478.11 CDJ82514.1 - 0.082 10.9 5.6 0.11 10.4 3.3 1.8 1 1 1 2 2 2 0 Prominin HAUS6_N PF14661.6 CDJ82514.1 - 0.087 12.4 12.4 0.077 12.6 6.7 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus FlxA PF14282.6 CDJ82514.1 - 0.088 12.8 6.9 0.15 12.0 3.4 2.8 1 1 1 2 2 2 0 FlxA-like protein DUF5401 PF17380.2 CDJ82514.1 - 0.094 10.8 11.3 0.11 10.5 11.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF948 PF06103.11 CDJ82514.1 - 0.11 12.8 1.9 0.42 10.9 0.5 2.5 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) FliJ PF02050.16 CDJ82514.1 - 0.11 12.8 12.5 0.32 11.2 8.0 2.7 1 1 1 2 2 2 0 Flagellar FliJ protein Baculo_PEP_C PF04513.12 CDJ82514.1 - 0.13 12.3 1.3 0.59 10.2 0.5 2.2 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus BRE1 PF08647.11 CDJ82514.1 - 0.14 12.3 20.6 0.23 11.6 4.0 3.3 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase DUF1515 PF07439.11 CDJ82514.1 - 0.14 12.2 8.2 0.17 11.9 2.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1515) YtxH PF12732.7 CDJ82514.1 - 0.14 12.7 1.2 18 5.9 0.3 2.5 2 1 0 2 2 2 0 YtxH-like protein IFT57 PF10498.9 CDJ82514.1 - 0.18 10.8 8.7 0.41 9.6 8.8 1.6 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 PRKG1_interact PF15898.5 CDJ82514.1 - 0.2 12.6 18.1 0.065 14.1 10.8 2.4 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain Spc24 PF08286.11 CDJ82514.1 - 0.2 11.9 14.1 0.56 10.5 2.4 3.2 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 LPP PF04728.13 CDJ82514.1 - 0.22 11.9 3.9 1.7 9.1 0.4 3.1 3 1 0 3 3 2 0 Lipoprotein leucine-zipper DUF1640 PF07798.11 CDJ82514.1 - 0.24 11.4 17.2 0.69 9.9 3.9 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1640) FapA PF03961.13 CDJ82514.1 - 0.25 9.9 14.2 0.093 11.3 9.6 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A TMPIT PF07851.13 CDJ82514.1 - 0.26 10.5 8.9 0.42 9.8 3.5 2.1 1 1 1 2 2 2 0 TMPIT-like protein GCN5L1 PF06320.13 CDJ82514.1 - 0.26 11.4 6.7 0.6 10.3 0.5 3.0 1 1 2 3 3 3 0 GCN5-like protein 1 (GCN5L1) She9_MDM33 PF05546.11 CDJ82514.1 - 0.28 11.0 7.6 0.35 10.6 2.3 2.5 1 1 1 2 2 2 0 She9 / Mdm33 family AAA_13 PF13166.6 CDJ82514.1 - 0.29 9.7 10.6 0.96 8.0 10.7 1.6 1 1 0 1 1 1 0 AAA domain CCDC144C PF14915.6 CDJ82514.1 - 0.31 10.1 16.3 0.78 8.8 16.3 1.5 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region DUF3450 PF11932.8 CDJ82514.1 - 0.35 10.2 13.4 2.5 7.4 8.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) BCAS2 PF05700.11 CDJ82514.1 - 0.35 10.5 10.1 0.78 9.4 5.6 2.3 1 1 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) bZIP_1 PF00170.21 CDJ82514.1 - 0.35 11.0 21.5 0.1 12.7 4.8 3.9 2 2 1 3 3 3 0 bZIP transcription factor Rho_Binding PF08912.11 CDJ82514.1 - 0.4 11.5 15.8 0.29 12.0 2.5 3.4 2 2 1 3 3 3 0 Rho Binding GIT_CC PF16559.5 CDJ82514.1 - 0.43 10.5 6.6 4.1 7.4 1.0 2.8 3 0 0 3 3 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF5320 PF17253.2 CDJ82514.1 - 0.43 11.7 11.6 1.7 9.7 1.9 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5320) BLOC1_2 PF10046.9 CDJ82514.1 - 0.45 10.8 11.2 7.8 6.9 2.7 2.8 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.9 CDJ82514.1 - 0.46 9.5 17.1 0.055 12.6 8.5 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prefoldin PF02996.17 CDJ82514.1 - 0.56 10.1 15.8 1.8 8.5 1.7 3.3 3 0 0 3 3 3 0 Prefoldin subunit bZIP_2 PF07716.15 CDJ82514.1 - 0.57 10.3 29.6 0.3 11.2 4.1 4.6 2 2 2 4 4 4 0 Basic region leucine zipper Fib_alpha PF08702.10 CDJ82514.1 - 0.64 10.2 8.5 0.79 9.9 6.2 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Sec34 PF04136.15 CDJ82514.1 - 0.73 9.7 6.1 2.8 7.8 0.4 3.0 1 1 1 3 3 3 0 Sec34-like family KASH_CCD PF14662.6 CDJ82514.1 - 0.74 9.6 17.4 13 5.5 17.4 2.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH FPP PF05911.11 CDJ82514.1 - 0.74 7.9 15.8 0.34 9.0 6.3 1.9 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF4446 PF14584.6 CDJ82514.1 - 0.75 9.8 10.7 2.2 8.3 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) DUF4988 PF16378.5 CDJ82514.1 - 0.76 9.4 3.8 0.95 9.1 0.6 2.4 2 1 1 3 3 2 0 Domain of unknown function KELK PF15796.5 CDJ82514.1 - 0.77 10.3 16.5 0.36 11.3 9.4 2.6 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase FliD_C PF07195.12 CDJ82514.1 - 0.8 9.1 9.5 1.3 8.4 3.5 2.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF4140 PF13600.6 CDJ82514.1 - 0.83 10.1 14.7 5.4 7.5 1.4 3.3 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) HIP1_clath_bdg PF16515.5 CDJ82514.1 - 0.96 10.1 12.1 2.3 8.9 8.7 2.7 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 NYD-SP28_assoc PF14775.6 CDJ82514.1 - 1.2 9.2 11.4 7.1 6.8 2.6 3.5 3 1 0 3 3 3 0 Sperm tail C-terminal domain Swi5 PF07061.11 CDJ82514.1 - 1.2 9.2 10.6 3.2 7.9 1.0 3.4 1 1 2 3 3 3 0 Swi5 JAKMIP_CC3 PF16034.5 CDJ82514.1 - 1.3 8.9 16.9 2.6 7.9 11.4 2.4 1 1 0 2 2 2 0 JAKMIP CC3 domain ABC_tran_CTD PF16326.5 CDJ82514.1 - 1.4 9.2 18.8 0.36 11.1 4.5 3.3 2 1 1 3 3 3 0 ABC transporter C-terminal domain RILP PF11461.8 CDJ82514.1 - 1.4 9.2 9.9 0.6 10.4 1.7 2.6 1 1 1 2 2 2 0 Rab interacting lysosomal protein Lipoprotein_20 PF13942.6 CDJ82514.1 - 1.5 8.7 11.1 0.13 12.2 2.2 2.5 1 1 0 2 2 2 0 YfhG lipoprotein PilO PF04350.13 CDJ82514.1 - 1.5 8.9 7.5 0.27 11.4 3.9 1.7 2 0 0 2 2 1 0 Pilus assembly protein, PilO Mt_ATP-synt_B PF05405.14 CDJ82514.1 - 1.6 8.3 7.8 0.39 10.3 3.9 2.0 2 1 0 2 2 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Glyco_transf_18 PF15024.6 CDJ82514.1 - 1.6 7.2 5.8 2.8 6.4 0.7 2.0 1 1 1 2 2 2 0 Glycosyltransferase family 18 DUF4200 PF13863.6 CDJ82514.1 - 2.1 8.8 22.9 14 6.1 13.4 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TSC22 PF01166.18 CDJ82514.1 - 2.1 8.7 17.0 0.95 9.8 3.1 4.2 3 1 1 4 4 4 0 TSC-22/dip/bun family STAT_alpha PF01017.20 CDJ82514.1 - 2.1 8.2 9.7 3.2 7.6 8.2 1.9 1 1 1 2 2 2 0 STAT protein, all-alpha domain DUF724 PF05266.14 CDJ82514.1 - 2.3 8.0 16.0 5.2 6.8 10.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) CC2-LZ PF16516.5 CDJ82514.1 - 2.4 8.6 16.5 7.1 7.1 0.4 3.2 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF1633 PF07794.11 CDJ82514.1 - 2.4 6.2 6.9 0.12 10.5 0.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1633) DUF1192 PF06698.11 CDJ82514.1 - 2.5 8.2 17.2 0.15 12.1 4.6 3.4 3 1 1 4 4 2 0 Protein of unknown function (DUF1192) FAP206 PF12018.8 CDJ82514.1 - 2.6 7.5 7.3 4 6.9 4.3 2.0 1 1 1 2 2 2 0 Domain of unknown function Csm1_N PF18504.1 CDJ82514.1 - 2.8 8.3 13.7 3 8.3 0.5 3.5 3 0 0 3 3 3 0 Csm1 N-terminal domain SPATA24 PF15175.6 CDJ82514.1 - 3.1 7.7 13.4 20 5.0 5.3 2.1 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 PEARLI-4 PF05278.12 CDJ82514.1 - 3.3 7.2 16.1 0.79 9.3 9.3 2.2 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) NRBF2 PF08961.10 CDJ82514.1 - 3.6 7.1 14.5 0.71 9.4 9.5 2.1 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator Exonuc_VII_L PF02601.15 CDJ82514.1 - 3.8 7.0 9.5 7.4 6.0 9.6 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit Cnn_1N PF07989.11 CDJ82514.1 - 3.8 7.7 15.9 3.5 7.9 3.2 3.4 2 2 1 3 3 3 0 Centrosomin N-terminal motif 1 Cep57_CLD_2 PF14197.6 CDJ82514.1 - 4.1 7.6 19.2 3.1 8.0 3.0 3.4 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 YojJ PF10372.9 CDJ82514.1 - 4.3 7.5 6.0 2.9 8.0 0.8 2.8 2 1 1 3 3 2 0 Bacterial membrane-spanning protein N-terminus TolA_bind_tri PF16331.5 CDJ82514.1 - 4.5 7.4 13.1 0.69 10.0 0.8 3.3 2 2 1 3 3 3 0 TolA binding protein trimerisation FAM76 PF16046.5 CDJ82514.1 - 4.6 6.5 11.7 11 5.3 11.3 1.7 1 1 1 2 2 2 0 FAM76 protein TPD52 PF04201.15 CDJ82514.1 - 5 6.7 14.8 9.6 5.8 5.8 2.7 2 1 1 3 3 2 0 Tumour protein D52 family Takusan PF04822.13 CDJ82514.1 - 5.3 7.0 21.4 14 5.7 0.3 3.8 1 1 1 2 2 2 0 Takusan Sec2p PF06428.11 CDJ82514.1 - 5.4 7.1 16.3 3.1 7.8 10.7 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF641 PF04859.12 CDJ82514.1 - 6.3 7.2 14.5 0.85 10.0 2.2 3.0 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) DMPK_coil PF08826.10 CDJ82514.1 - 6.3 7.0 17.6 4.9 7.3 1.9 3.9 2 2 1 3 3 2 0 DMPK coiled coil domain like Cep57_MT_bd PF06657.13 CDJ82514.1 - 6.4 7.3 12.6 5.9 7.4 1.4 2.9 2 1 1 3 3 2 0 Centrosome microtubule-binding domain of Cep57 AAA_11 PF13086.6 CDJ82514.1 - 6.4 6.5 8.7 16 5.2 8.7 1.7 1 1 0 1 1 1 0 AAA domain Nas2_N PF18265.1 CDJ82514.1 - 6.7 6.7 7.7 1.8 8.6 0.3 3.1 3 1 0 3 3 2 0 Nas2 N_terminal domain WD40_alt PF14077.6 CDJ82514.1 - 7.1 6.6 11.4 1.2 9.0 1.9 3.3 2 1 1 3 3 3 0 Alternative WD40 repeat motif Tho2 PF11262.8 CDJ82514.1 - 8.3 5.5 10.2 1.4e+02 1.5 9.8 2.3 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Tup_N PF08581.10 CDJ82514.1 - 9.3 6.6 14.6 1.2e+02 3.1 0.1 3.5 1 1 1 2 2 2 0 Tup N-terminal Occludin_ELL PF07303.13 CDJ82514.1 - 9.3 7.0 9.2 9 7.1 4.6 2.6 1 1 1 2 2 2 0 Occludin homology domain HSF_DNA-bind PF00447.17 CDJ82515.1 - 1.7e-28 99.0 0.3 4e-28 97.9 0.3 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding ZYG-11_interact PF05884.12 CDJ82515.1 - 0.0014 18.1 3.6 0.053 12.9 3.3 2.2 2 0 0 2 2 2 1 Interactor of ZYG-11 LRRFIP PF09738.9 CDJ82515.1 - 0.0034 16.9 1.7 0.0065 16.0 1.7 1.4 1 0 0 1 1 1 1 LRRFIP family TMF_DNA_bd PF12329.8 CDJ82515.1 - 0.029 14.3 3.2 0.072 13.1 3.2 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Speriolin_N PF15058.6 CDJ82515.1 - 0.086 12.9 4.6 0.19 11.8 4.6 1.5 1 0 0 1 1 1 0 Speriolin N terminus GIT_CC PF16559.5 CDJ82515.1 - 5.7 6.9 10.5 4.6 7.2 6.0 2.6 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Btz PF09405.10 CDJ82517.1 - 3.4e-13 50.0 9.8 3.4e-13 50.0 9.8 5.9 2 1 1 3 3 3 1 CASC3/Barentsz eIF4AIII binding Ribosomal_L14e PF01929.17 CDJ82518.1 - 1.7e-24 86.1 8.5 2.4e-24 85.6 8.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 CDJ82518.1 - 0.0017 18.2 3.6 0.0046 16.9 3.6 1.8 1 0 0 1 1 1 1 KOW motif Corona_NS2 PF04753.12 CDJ82519.1 - 0.14 12.8 0.0 0.24 12.0 0.0 1.3 1 0 0 1 1 1 0 Coronavirus non-structural protein NS2 Methyltransf_21 PF05050.12 CDJ82520.1 - 0.0023 18.0 0.0 0.0033 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain DUF5412 PF17428.2 CDJ82520.1 - 0.13 12.1 0.4 0.29 11.0 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5412) Cation_efflux PF01545.21 CDJ82521.1 - 4e-16 59.4 2.8 4.8e-16 59.1 2.8 1.1 1 0 0 1 1 1 1 Cation efflux family DUF5056 PF16479.5 CDJ82521.1 - 0.28 11.4 3.6 0.26 11.5 0.9 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5056) PLDc_3 PF13918.6 CDJ82523.1 - 2.9e-32 111.7 0.0 6.2e-32 110.7 0.0 1.6 2 0 0 2 2 2 1 PLD-like domain PLDc_2 PF13091.6 CDJ82523.1 - 2.3e-24 85.8 0.0 7.6e-13 48.5 0.0 2.4 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CDJ82523.1 - 3.3e-10 39.7 5.7 1.7e-05 24.8 1.1 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 CDJ82523.1 - 0.032 13.4 0.0 0.27 10.4 0.0 2.3 2 1 0 2 2 2 0 Archaeal transcriptional regulator TrmB 7TM_GPCR_Str PF10326.9 CDJ82524.1 - 4e-07 29.7 4.7 5.4e-07 29.2 3.8 1.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srh PF10318.9 CDJ82524.1 - 5.9e-06 25.5 0.6 5.9e-06 25.5 0.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Srd PF10317.9 CDJ82524.1 - 8.1e-05 22.0 2.7 8.8e-05 21.8 2.7 1.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Srj PF10319.9 CDJ82524.1 - 0.00028 20.4 1.6 0.0003 20.3 1.6 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Sri PF10327.9 CDJ82524.1 - 0.0091 15.2 0.4 0.0091 15.2 0.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri Trypsin PF00089.26 CDJ82525.1 - 2.9e-22 79.6 0.1 9.5e-22 77.9 0.1 1.7 1 1 0 1 1 1 1 Trypsin NIDO PF06119.14 CDJ82526.1 - 4.7e-31 107.6 4.4 9.6e-16 58.5 0.8 2.8 2 0 0 2 2 2 2 Nidogen-like cEGF PF12662.7 CDJ82526.1 - 3e-07 30.3 12.8 0.00029 20.7 2.4 2.8 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF_CA PF07645.15 CDJ82526.1 - 3.7e-07 30.2 9.4 3.7e-07 30.2 9.4 3.6 2 1 1 3 3 1 1 Calcium-binding EGF domain EGF_3 PF12947.7 CDJ82526.1 - 5e-07 29.8 8.7 5e-07 29.8 8.7 3.6 4 0 0 4 4 3 2 EGF domain EGF PF00008.27 CDJ82526.1 - 7.4e-05 23.0 9.3 7.4e-05 23.0 9.3 3.5 4 0 0 4 4 3 1 EGF-like domain TMEM154 PF15102.6 CDJ82526.1 - 0.00013 21.8 2.5 0.00013 21.8 2.5 3.3 1 1 2 3 3 2 1 TMEM154 protein family hEGF PF12661.7 CDJ82526.1 - 0.0092 16.6 4.0 0.0092 16.6 4.0 4.0 4 0 0 4 4 4 1 Human growth factor-like EGF Insulin_TMD PF17870.1 CDJ82526.1 - 0.021 14.9 0.3 0.042 13.9 0.3 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4448 PF14610.6 CDJ82526.1 - 0.021 14.6 0.1 0.046 13.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Adeno_E3_CR2 PF02439.15 CDJ82526.1 - 0.038 13.7 3.5 0.069 12.9 3.5 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Orf78 PF06024.12 CDJ82526.1 - 0.04 14.2 0.4 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 Orf78 (ac78) Sugar_tr PF00083.24 CDJ82527.1 - 1.4e-20 73.6 12.3 1.8e-20 73.3 12.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ82527.1 - 1.9e-14 53.4 11.4 1.9e-14 53.4 11.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily HHH_8 PF14716.6 CDJ82527.1 - 0.02 15.2 0.0 0.042 14.2 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Multi_Drug_Res PF00893.19 CDJ82527.1 - 0.93 10.2 5.8 0.26 12.0 0.4 2.7 2 0 0 2 2 2 0 Small Multidrug Resistance protein DUF2897 PF11446.8 CDJ82527.1 - 1.3 9.0 3.6 0.61 10.0 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) MFS_1_like PF12832.7 CDJ82527.1 - 2.6 6.8 10.6 4.2 6.1 2.2 2.3 1 1 1 2 2 2 0 MFS_1 like family Orthoreo_P10 PF07204.11 CDJ82528.1 - 0.36 10.8 13.1 1.3 9.0 0.7 3.4 3 0 0 3 3 3 0 Orthoreovirus membrane fusion protein p10 ShK PF01549.24 CDJ82529.1 - 0.016 15.7 3.3 0.025 15.1 3.3 1.3 1 0 0 1 1 1 0 ShK domain-like PHD PF00628.29 CDJ82530.1 - 5.7e-19 67.7 24.6 1.5e-09 37.6 8.5 3.6 2 1 1 3 3 3 2 PHD-finger Requiem_N PF14051.6 CDJ82530.1 - 2.6e-18 66.0 4.1 5.9e-18 64.8 4.1 1.6 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. Prok-RING_1 PF14446.6 CDJ82530.1 - 1.2e-06 28.4 22.7 0.00028 20.7 1.8 3.6 3 1 1 4 4 4 2 Prokaryotic RING finger family 1 PHD_4 PF16866.5 CDJ82530.1 - 0.019 15.0 8.1 0.019 15.0 8.1 3.2 2 1 1 3 3 3 0 PHD-finger OrfB_Zn_ribbon PF07282.11 CDJ82530.1 - 0.02 14.8 0.4 0.02 14.8 0.4 2.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Nop14 PF04147.12 CDJ82530.1 - 0.033 12.4 1.6 0.039 12.2 1.6 1.1 1 0 0 1 1 1 0 Nop14-like family ICAP-1_inte_bdg PF10480.9 CDJ82530.1 - 0.28 11.2 8.7 0.56 10.2 8.7 1.5 1 0 0 1 1 1 0 Beta-1 integrin binding protein zf-PHD-like PF15446.6 CDJ82530.1 - 0.33 10.6 15.3 1.4 8.5 1.1 3.4 2 1 0 3 3 3 0 PHD/FYVE-zinc-finger like domain Zf_RING PF16744.5 CDJ82530.1 - 0.44 10.7 22.6 0.56 10.4 4.1 4.6 2 1 2 4 4 4 0 KIAA1045 RING finger Collagen_mid PF15984.5 CDJ82531.1 - 4.7 6.9 25.2 26 4.5 1.9 2.2 1 1 1 2 2 2 0 Bacterial collagen, middle region TSP_1 PF00090.19 CDJ82532.1 - 3.6e-14 52.7 183.3 2.6e-06 27.6 15.0 10.2 9 0 0 9 9 9 9 Thrombospondin type 1 domain RVT_1 PF00078.27 CDJ82533.1 - 6.3e-19 68.4 0.0 1.1e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_12 PF13087.6 CDJ82534.1 - 6e-36 124.0 0.0 7.4e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CDJ82534.1 - 0.00045 20.0 0.0 0.00054 19.8 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 CDJ82534.1 - 0.0028 17.4 1.6 0.026 14.4 0.0 2.8 3 1 0 3 3 3 1 UvrD-like helicase C-terminal domain gag-asp_proteas PF13975.6 CDJ82535.1 - 2.9e-05 24.5 0.0 9.3e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 CDJ82535.1 - 0.00022 21.1 1.7 0.00022 21.1 1.7 2.3 3 0 0 3 3 3 1 Zinc knuckle Asp_protease_2 PF13650.6 CDJ82535.1 - 0.0036 17.9 0.0 0.01 16.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Dimerisation2 PF16864.5 CDJ82535.1 - 0.028 14.4 1.5 8.2 6.5 0.1 3.0 3 0 0 3 3 3 0 Dimerisation domain HTH_24 PF13412.6 CDJ82535.1 - 0.048 13.2 0.0 0.16 11.5 0.0 2.0 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Cu_amine_oxidN1 PF07833.11 CDJ82535.1 - 0.1 13.1 0.0 23 5.6 0.0 2.9 3 0 0 3 3 3 0 Copper amine oxidase N-terminal domain RVP PF00077.20 CDJ82535.1 - 0.11 12.8 0.1 0.42 10.9 0.1 2.1 1 1 0 1 1 1 0 Retroviral aspartyl protease SlyX PF04102.12 CDJ82535.1 - 5.4 7.7 5.5 2.8 8.6 2.3 2.2 2 0 0 2 2 2 0 SlyX Glutaredoxin PF00462.24 CDJ82537.1 - 7.2e-37 125.4 0.0 6.4e-17 61.5 0.0 3.3 3 0 0 3 3 3 2 Glutaredoxin Thioredoxin PF00085.20 CDJ82537.1 - 5e-14 52.1 0.0 1.2e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CDJ82537.1 - 0.00014 22.2 0.0 0.005 17.3 0.0 2.9 3 1 0 3 3 3 1 Thioredoxin-like domain SH3BGR PF04908.15 CDJ82537.1 - 0.002 18.2 0.0 0.44 10.7 0.0 2.6 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein TraF PF13728.6 CDJ82537.1 - 0.0033 17.3 0.0 8.6 6.1 0.0 3.1 3 0 0 3 3 3 2 F plasmid transfer operon protein Fumerase_C PF05683.12 CDJ82537.1 - 0.056 12.8 0.0 10 5.4 0.0 2.2 2 0 0 2 2 2 0 Fumarase C-terminus PMI_typeI PF01238.21 CDJ82540.1 - 5.6e-106 354.9 0.0 6.6e-106 354.7 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 CDJ82540.1 - 0.075 12.7 0.0 7.2 6.4 0.0 2.6 2 0 0 2 2 2 0 Cupin domain VapB_antitoxin PF09957.9 CDJ82540.1 - 0.1 12.5 0.1 17 5.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial antitoxin of type II TA system, VapB YcbB PF08664.10 CDJ82540.1 - 0.17 12.0 0.1 0.96 9.5 0.0 1.9 2 0 0 2 2 2 0 YcbB domain AraC_binding PF02311.19 CDJ82540.1 - 0.18 11.7 0.1 5.8 6.8 0.0 2.8 3 0 0 3 3 3 0 AraC-like ligand binding domain Na_H_Exchanger PF00999.21 CDJ82541.1 - 1.1e-15 57.3 36.3 2.9e-15 55.9 26.2 2.5 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.21 CDJ82542.1 - 7.6e-25 87.5 37.7 9.5e-16 57.6 21.6 2.2 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family Zn_peptidase_2 PF04298.12 CDJ82542.1 - 0.87 8.9 9.5 0.2 11.0 0.4 3.3 2 1 1 3 3 3 0 Putative neutral zinc metallopeptidase Aminotran_1_2 PF00155.21 CDJ82543.1 - 9.4e-49 166.5 0.0 1.1e-48 166.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CDJ82543.1 - 0.0025 16.8 0.0 0.0042 16.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DUF992 PF06186.11 CDJ82543.1 - 0.071 13.0 0.4 1.2 8.9 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF992) Beta_elim_lyase PF01212.21 CDJ82543.1 - 0.15 11.3 0.0 0.31 10.3 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase DDE_Tnp_IS1595 PF12762.7 CDJ82544.1 - 7.1e-16 58.6 0.0 8.8e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS66 PF03050.14 CDJ82544.1 - 0.0012 18.4 0.1 0.0014 18.1 0.1 1.1 1 0 0 1 1 1 1 Transposase IS66 family DUF4286 PF14114.6 CDJ82544.1 - 0.069 13.7 0.1 0.1 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) DAGK_cat PF00781.24 CDJ82545.1 - 2.1e-21 75.8 0.0 3.4e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain HTH_48 PF17906.1 CDJ82546.1 - 9.7e-16 57.6 0.1 1.4e-15 57.2 0.1 1.2 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_50 PF18024.1 CDJ82546.1 - 0.002 17.7 0.0 0.0034 17.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 CDJ82546.1 - 0.0021 17.8 0.1 0.14 12.0 0.1 2.9 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 CDJ82546.1 - 0.0089 16.6 0.0 0.013 16.1 0.0 1.4 1 1 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 CDJ82546.1 - 0.022 14.8 0.3 0.36 10.9 0.1 2.3 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_IS630 PF01710.16 CDJ82546.1 - 0.048 13.7 0.0 0.056 13.5 0.0 1.1 1 0 0 1 1 1 0 Transposase HTH_28 PF13518.6 CDJ82546.1 - 0.14 12.3 0.2 0.87 9.8 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Folate_carrier PF01770.18 CDJ82547.1 - 0.11 11.2 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier Dna2 PF08696.11 CDJ82548.1 - 9.8e-47 159.4 0.0 2.3e-46 158.2 0.0 1.7 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.6 CDJ82548.1 - 1.2e-45 155.6 0.1 2.2e-45 154.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ82548.1 - 6.3e-32 111.4 0.7 2.5e-16 60.3 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 CDJ82548.1 - 4.3e-13 49.4 0.0 2.9e-12 46.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain PDDEXK_1 PF12705.7 CDJ82548.1 - 1.1e-10 41.9 0.0 1.7e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_19 PF13245.6 CDJ82548.1 - 2.2e-10 41.1 0.0 8.4e-10 39.2 0.0 2.1 2 0 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.18 CDJ82548.1 - 5.7e-08 32.8 0.1 0.0033 17.2 0.0 3.5 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Cas_Cas4 PF01930.17 CDJ82548.1 - 9.1e-06 25.9 0.1 0.00086 19.5 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function DUF83 Helicase_RecD PF05127.14 CDJ82548.1 - 8.5e-05 22.5 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 Helicase PglL_A PF15864.5 CDJ82548.1 - 0.0018 17.9 0.0 0.004 16.8 0.0 1.5 1 0 0 1 1 1 1 Protein glycosylation ligase UvrD_C_2 PF13538.6 CDJ82548.1 - 0.0044 16.8 0.1 0.012 15.4 0.1 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain cobW PF02492.19 CDJ82548.1 - 0.0046 16.6 0.0 0.0091 15.6 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain UvrD-helicase PF00580.21 CDJ82548.1 - 0.012 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain PhoH PF02562.16 CDJ82548.1 - 0.03 13.8 0.2 17 4.8 0.0 3.4 3 1 1 4 4 4 0 PhoH-like protein DUF2075 PF09848.9 CDJ82548.1 - 0.035 13.3 0.0 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 CDJ82548.1 - 0.038 13.1 0.1 0.072 12.1 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.22 CDJ82548.1 - 0.13 11.8 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_31 PF13614.6 CDJ82548.1 - 1.7 8.5 4.9 14 5.5 3.3 2.8 2 1 0 2 2 2 0 AAA domain Peptidase_M20 PF01546.28 CDJ82549.1 - 2.9e-34 118.6 0.0 5.8e-33 114.3 0.0 2.2 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CDJ82549.1 - 9.7e-12 44.8 0.0 1.7e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CDJ82549.1 - 0.00048 19.9 0.0 0.00081 19.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 CDJ82549.1 - 0.002 17.2 0.0 0.0045 16.0 0.0 1.5 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase VF530 PF09905.9 CDJ82549.1 - 0.07 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 DNA-binding protein VF530 DUF1129 PF06570.11 CDJ82550.1 - 0.0022 17.5 2.5 0.0025 17.4 2.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1129) SUR7 PF06687.12 CDJ82550.1 - 0.012 15.3 7.0 0.0088 15.7 5.9 1.4 1 1 0 1 1 1 0 SUR7/PalI family DUF373 PF04123.13 CDJ82550.1 - 0.88 9.0 6.9 1 8.7 6.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF373) NKAIN PF05640.14 CDJ82550.1 - 2.3 7.4 10.5 0.31 10.2 1.9 2.8 1 1 1 3 3 3 0 Na,K-Atpase Interacting protein RPN2_C PF18004.1 CDJ82551.1 - 0.23 11.3 6.5 0.26 11.2 6.5 1.0 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF1639 PF07797.14 CDJ82551.1 - 0.47 10.5 4.4 0.74 9.8 4.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1639) NPR3 PF03666.13 CDJ82551.1 - 1.4 7.6 8.3 1.8 7.3 8.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 CDJ82551.1 - 8.3 5.1 7.0 9.5 4.9 7.0 1.0 1 0 0 1 1 1 0 Presenilin Pheromone PF08015.11 CDJ82552.1 - 0.37 11.9 7.8 0.39 11.8 2.3 3.1 3 0 0 3 3 3 0 Fungal mating-type pheromone PRIMA1 PF16101.5 CDJ82552.1 - 0.48 10.5 3.0 1.4 8.9 3.0 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Nop14 PF04147.12 CDJ82552.1 - 0.68 8.1 5.9 0.88 7.7 5.9 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1642 PF07852.11 CDJ82555.1 - 0.00093 19.8 0.1 1.6 9.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1642) DUF4311 PF14188.6 CDJ82555.1 - 0.019 14.8 0.1 1.4 8.6 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4311) Neil1-DNA_bind PF09292.10 CDJ82555.1 - 0.029 14.3 1.3 7.5 6.6 0.2 2.7 2 0 0 2 2 2 0 Endonuclease VIII-like 1, DNA bind AHSP PF09236.10 CDJ82555.1 - 0.08 13.4 0.1 5.1 7.6 0.0 2.2 2 0 0 2 2 2 0 Alpha-haemoglobin stabilising protein Agenet PF05641.12 CDJ82556.1 - 0.085 13.3 0.1 0.14 12.6 0.1 1.4 1 0 0 1 1 1 0 Agenet domain 7TM_GPCR_Srsx PF10320.9 CDJ82557.1 - 2e-14 53.6 4.4 2.3e-14 53.4 4.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 CDJ82557.1 - 0.052 12.8 3.1 0.057 12.7 3.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Caveolin PF01146.17 CDJ82558.1 - 1.3e-36 125.5 0.4 1.6e-36 125.2 0.4 1.1 1 0 0 1 1 1 1 Caveolin YbgT_YccB PF08173.11 CDJ82558.1 - 0.32 11.2 2.9 0.71 10.1 2.9 1.6 1 1 0 1 1 1 0 Membrane bound YbgT-like protein PKK PF12474.8 CDJ82559.1 - 1.9e-50 170.6 79.8 1.7e-27 96.2 41.2 4.3 3 1 2 5 5 5 2 Polo kinase kinase HTH_26 PF13443.6 CDJ82560.1 - 0.00096 19.5 0.0 0.0026 18.2 0.0 1.7 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain DUF2095 PF09868.9 CDJ82560.1 - 0.0043 17.0 0.7 0.014 15.4 0.1 1.9 1 1 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2095) MarR_2 PF12802.7 CDJ82560.1 - 0.0078 16.1 0.2 0.017 15.0 0.2 1.6 1 1 0 1 1 1 1 MarR family HTH_IclR PF09339.10 CDJ82560.1 - 0.008 16.0 0.1 0.014 15.2 0.1 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_3 PF01381.22 CDJ82560.1 - 0.023 14.8 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix DUF3602 PF12223.8 CDJ82560.1 - 0.025 15.2 1.4 0.038 14.6 0.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3602) PolyA_pol PF01743.20 CDJ82560.1 - 0.029 14.8 0.3 0.033 14.6 0.3 1.1 1 0 0 1 1 1 0 Poly A polymerase head domain HTH_Tnp_ISL3 PF13542.6 CDJ82560.1 - 0.04 13.3 0.1 0.069 12.6 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.6 CDJ82560.1 - 0.054 13.1 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 CDJ82560.1 - 0.06 13.1 2.7 0.12 12.2 0.7 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain CENP-B_N PF04218.13 CDJ82560.1 - 0.072 12.7 0.0 0.18 11.4 0.0 1.8 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Zn_protease PF05618.11 CDJ82560.1 - 0.089 12.7 1.6 0.13 12.2 0.7 1.7 1 1 1 2 2 2 0 Putative ATP-dependant zinc protease Curto_V2 PF07325.11 CDJ82560.1 - 0.16 11.8 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 Curtovirus V2 protein RVT_1 PF00078.27 CDJ82561.1 - 4.6e-08 32.9 0.0 1.2e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PAX PF00292.18 CDJ82562.1 - 5.2e-10 39.3 0.1 6.8e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 CDJ82562.1 - 2.1e-07 30.5 0.0 3.4e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 CDJ82562.1 - 8.4e-07 28.9 0.2 1.2e-06 28.4 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 CDJ82562.1 - 1.2e-06 28.5 0.1 2e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 CDJ82562.1 - 0.011 15.4 0.1 0.022 14.5 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Neur_chan_LBD PF02931.23 CDJ82563.1 - 3.9e-52 176.8 0.0 5.3e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ82563.1 - 1.2e-41 143.3 5.9 5.1e-41 141.3 5.9 1.9 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region HTH_33 PF13592.6 CDJ82563.1 - 0.094 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Neur_chan_memb PF02932.16 CDJ82564.1 - 9e-09 35.7 0.2 1.2e-08 35.4 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CDJ82564.1 - 6.9e-08 32.2 0.1 0.0027 17.2 0.0 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain SCVP PF17619.2 CDJ82565.1 - 4.5e-24 85.1 0.1 4.5e-24 85.1 0.1 1.5 2 0 0 2 2 2 1 Secreted clade V proteins POX PF07526.11 CDJ82565.1 - 0.027 15.1 0.1 0.034 14.7 0.1 1.2 1 0 0 1 1 1 0 Associated with HOX FAM176 PF14851.6 CDJ82565.1 - 0.029 14.0 0.2 0.037 13.7 0.2 1.2 1 0 0 1 1 1 0 FAM176 family DUF4576 PF15144.6 CDJ82565.1 - 0.095 12.6 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) HDA2-3 PF11496.8 CDJ82565.1 - 0.23 10.6 2.1 1.4 8.0 1.3 1.8 1 1 1 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 SCVP PF17619.2 CDJ82566.1 - 4.8e-27 94.7 0.2 7.9e-27 94.0 0.2 1.3 1 0 0 1 1 1 1 Secreted clade V proteins Dicty_REP PF05086.12 CDJ82566.1 - 0.033 12.2 3.2 0.035 12.1 3.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3405 PF11885.8 CDJ82566.1 - 0.085 11.4 0.1 0.095 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) DUF3439 PF11921.8 CDJ82566.1 - 0.12 12.4 10.8 0.19 11.7 10.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 CDJ82566.1 - 0.56 8.4 9.9 0.65 8.1 9.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 VWA_N2 PF16164.5 CDJ82566.1 - 1 9.5 4.1 2 8.6 4.1 1.4 1 0 0 1 1 1 0 VWA N-terminal SCVP PF17619.2 CDJ82567.1 - 1.8e-24 86.4 0.0 2.7e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Secreted clade V proteins SCVP PF17619.2 CDJ82568.1 - 2.2e-24 86.1 0.0 3.5e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Secreted clade V proteins SCVP PF17619.2 CDJ82569.1 - 6.8e-27 94.2 0.5 1e-26 93.6 0.5 1.3 1 0 0 1 1 1 1 Secreted clade V proteins Dicty_REP PF05086.12 CDJ82569.1 - 0.032 12.2 1.8 0.036 12.1 1.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF669 PF05037.13 CDJ82569.1 - 0.15 12.1 1.4 0.29 11.3 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF669) SCVP PF17619.2 CDJ82570.1 - 1.3e-23 83.6 0.0 2.7e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Secreted clade V proteins Syntaxin-18_N PF10496.9 CDJ82570.1 - 0.096 13.0 2.7 0.23 11.7 0.2 2.4 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus DUF4576 PF15144.6 CDJ82570.1 - 0.15 11.9 0.1 0.28 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) SCVP PF17619.2 CDJ82571.1 - 1e-26 93.6 0.3 1.6e-26 93.0 0.3 1.3 1 0 0 1 1 1 1 Secreted clade V proteins Dicty_REP PF05086.12 CDJ82571.1 - 0.069 11.1 3.0 0.08 10.9 3.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.8 CDJ82571.1 - 0.53 10.2 10.4 0.098 12.6 6.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) HTH_48 PF17906.1 CDJ82572.1 - 8.1e-19 67.5 1.0 1.5e-18 66.6 1.0 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_23 PF13384.6 CDJ82572.1 - 2.8e-08 33.3 0.3 0.00019 21.1 0.0 2.5 3 0 0 3 3 3 2 Homeodomain-like domain HTH_28 PF13518.6 CDJ82572.1 - 2.3e-06 27.6 0.1 0.0078 16.3 0.0 2.8 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_50 PF18024.1 CDJ82572.1 - 2.7e-06 26.9 0.0 4.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 CDJ82572.1 - 3.9e-06 26.5 0.8 6.1e-06 25.9 0.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_IS630 PF01710.16 CDJ82572.1 - 3e-05 24.1 0.0 3.2e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 CDJ82572.1 - 6.4e-05 23.5 0.0 0.00011 22.8 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain Terminase_5 PF06056.12 CDJ82572.1 - 0.0003 20.6 0.0 0.056 13.3 0.0 2.3 2 0 0 2 2 2 1 Putative ATPase subunit of terminase (gpP-like) HTH_29 PF13551.6 CDJ82572.1 - 0.00031 20.7 0.1 0.0059 16.6 0.0 2.3 1 1 1 2 2 2 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 CDJ82572.1 - 0.00035 20.8 0.3 0.00098 19.3 0.1 1.7 2 0 0 2 2 2 1 Transposase HTH_Tnp_ISL3 PF13542.6 CDJ82572.1 - 0.0045 16.4 0.1 0.038 13.4 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 CDJ82572.1 - 0.0048 16.8 0.1 0.0076 16.2 0.1 1.3 1 0 0 1 1 1 1 HTH domain IF2_N PF04760.15 CDJ82572.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region HTH_Tnp_1 PF01527.20 CDJ82572.1 - 0.013 15.8 0.1 4.1 7.8 0.0 2.4 1 1 1 2 2 2 0 Transposase HTH_6 PF01418.17 CDJ82572.1 - 0.028 14.4 0.0 0.085 12.8 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family HTH_36 PF13730.6 CDJ82572.1 - 0.029 14.3 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_10 PF04967.12 CDJ82572.1 - 0.035 13.9 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 HTH DNA binding domain HTH_40 PF14493.6 CDJ82572.1 - 0.036 14.5 0.1 0.068 13.6 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 CDJ82572.1 - 0.065 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 CDJ82572.1 - 0.081 12.8 0.0 0.19 11.6 0.0 1.6 2 0 0 2 2 2 0 MarR family Sigma70_r4_2 PF08281.12 CDJ82572.1 - 0.095 12.4 0.1 1.2 8.9 0.1 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 NUMOD1 PF07453.13 CDJ82572.1 - 0.12 12.7 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 NUMOD1 domain HTH_5 PF01022.20 CDJ82572.1 - 0.12 12.3 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family GerE PF00196.19 CDJ82572.1 - 0.14 11.7 0.1 0.31 10.6 0.1 1.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Phage_terminase PF10668.9 CDJ82572.1 - 0.16 12.0 0.2 0.65 10.0 0.0 2.0 2 1 0 2 2 2 0 Phage terminase small subunit DUF4817 PF16087.5 CDJ82572.1 - 0.17 11.7 1.6 0.21 11.4 0.2 1.9 2 1 0 2 2 2 0 Helix-turn-helix domain (DUF4817) 7TM_GPCR_Srx PF10328.9 CDJ82573.1 - 2.3e-25 89.7 16.4 2.8e-25 89.4 16.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 CDJ82573.1 - 6e-06 25.8 8.0 7.5e-06 25.4 8.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srt PF10321.9 CDJ82573.1 - 0.0053 15.8 9.5 0.0065 15.5 9.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt 7tm_4 PF13853.6 CDJ82573.1 - 0.017 14.9 3.4 0.022 14.5 3.4 1.1 1 0 0 1 1 1 0 Olfactory receptor Serpentine_r_xa PF03383.15 CDJ82573.1 - 0.18 11.8 5.2 0.14 12.2 4.2 1.4 1 1 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa AMP-binding PF00501.28 CDJ82574.1 - 5.5e-45 153.7 0.0 6.7e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme CsoSCA PF08936.10 CDJ82574.1 - 0.032 12.9 0.0 0.055 12.1 0.0 1.3 2 0 0 2 2 2 0 Carboxysome Shell Carbonic Anhydrase Peptidase_M48_N PF16491.5 CDJ82575.1 - 6.5e-62 208.7 6.1 6.5e-62 208.7 6.1 2.1 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 CDJ82575.1 - 2.7e-45 154.6 0.0 3.5e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 DUF4538 PF15061.6 CDJ82575.1 - 0.13 12.0 1.9 0.32 10.8 1.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) EMC3_TMCO1 PF01956.16 CDJ82575.1 - 0.31 10.7 7.2 0.33 10.7 2.0 2.7 3 0 0 3 3 3 0 Integral membrane protein EMC3/TMCO1-like Pkinase PF00069.25 CDJ82576.1 - 2.2e-11 43.6 0.0 3e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ82576.1 - 6.7e-08 32.1 0.0 8.7e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Vps51 PF08700.11 CDJ82577.1 - 4.6e-22 77.9 3.3 4.6e-22 77.9 3.3 2.4 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.6 CDJ82577.1 - 4.9e-12 46.1 2.7 1.3e-11 44.7 2.7 1.8 1 0 0 1 1 1 1 Exocyst complex component Sec5 Dor1 PF04124.12 CDJ82577.1 - 1.5e-11 43.6 3.7 2.3e-11 43.0 2.0 2.1 2 0 0 2 2 2 1 Dor1-like family Vps54_N PF10475.9 CDJ82577.1 - 8.6e-07 28.5 3.4 1.9e-06 27.4 3.4 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 CDJ82577.1 - 4.8e-06 26.7 1.2 4.8e-06 26.7 1.2 2.9 3 1 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 CDJ82577.1 - 1.6e-05 25.1 4.6 6.7e-05 23.1 0.3 2.8 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Zw10 PF06248.13 CDJ82577.1 - 0.0028 16.3 0.4 0.0028 16.3 0.4 2.0 1 1 1 2 2 2 1 Centromere/kinetochore Zw10 Nab2 PF11517.8 CDJ82577.1 - 0.014 15.7 0.9 0.27 11.5 0.1 3.1 2 1 1 3 3 3 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Vps53_N PF04100.12 CDJ82577.1 - 0.024 13.6 5.4 0.045 12.7 5.4 1.4 1 0 0 1 1 1 0 Vps53-like, N-terminal 7TMR-HDED PF07697.11 CDJ82577.1 - 0.087 12.9 0.9 0.19 11.8 0.2 2.0 2 1 0 2 2 2 0 7TM-HD extracellular Occludin_ELL PF07303.13 CDJ82577.1 - 0.099 13.4 0.6 0.63 10.8 0.1 2.6 2 0 0 2 2 2 0 Occludin homology domain MutS_III PF05192.18 CDJ82577.1 - 0.29 11.3 2.6 3.8 7.7 0.0 2.8 1 1 0 2 2 2 0 MutS domain III RB_A PF01858.17 CDJ82578.1 - 1.7e-46 158.5 0.4 9.3e-46 156.1 0.1 2.3 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain RB_B PF01857.20 CDJ82578.1 - 8.6e-39 132.6 0.7 4.3e-38 130.3 0.0 2.5 3 0 0 3 3 3 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 CDJ82578.1 - 1.9e-19 69.6 1.7 2.2e-18 66.2 1.3 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3452) RVT_1 PF00078.27 CDJ82579.1 - 6.9e-31 107.5 0.0 4.5e-30 104.8 0.0 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MerT PF02411.15 CDJ82579.1 - 0.18 11.8 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 MerT mercuric transport protein HALZ PF02183.18 CDJ82580.1 - 0.093 13.0 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper DNA_PPF PF02916.15 CDJ82580.1 - 0.25 11.8 0.0 0.33 11.4 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase processivity factor MRG PF05712.13 CDJ82581.1 - 5.5e-29 100.9 0.0 8.5e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 CDJ82581.1 - 2.4e-06 27.3 1.6 2.4e-06 27.3 1.6 1.8 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.25 CDJ82582.1 - 6.2e-16 58.7 0.0 8.4e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDJ82582.1 - 5.7e-10 39.5 0.0 8e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDJ82582.1 - 4.9e-08 33.0 0.0 7.5e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CDJ82582.1 - 0.024 14.7 0.0 0.056 13.5 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Laminin_II PF06009.12 CDJ82583.1 - 0.0069 16.4 0.2 0.0076 16.3 0.2 1.1 1 0 0 1 1 1 1 Laminin Domain II MPS2 PF17060.5 CDJ82583.1 - 0.026 13.8 2.7 0.028 13.7 2.7 1.0 1 0 0 1 1 1 0 Monopolar spindle protein 2 Kelch_1 PF01344.25 CDJ82584.1 - 5.3e-84 275.6 7.3 1.2e-16 60.0 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CDJ82584.1 - 1e-46 155.8 3.1 3.4e-11 43.0 0.1 6.3 1 1 5 6 6 6 6 Kelch motif Kelch_2 PF07646.15 CDJ82584.1 - 6e-44 146.4 0.9 9.3e-10 38.1 0.0 6.3 6 0 0 6 6 6 6 Kelch motif BTB PF00651.31 CDJ82584.1 - 1e-30 106.2 0.1 2.1e-30 105.2 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 CDJ82584.1 - 2.1e-30 104.8 1.1 3.7e-30 104.1 0.4 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 CDJ82584.1 - 3.6e-28 97.3 0.2 0.00057 19.8 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ82584.1 - 1.4e-25 89.0 3.4 0.00038 20.7 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ82584.1 - 7.6e-13 48.1 3.1 0.05 13.6 0.1 6.2 6 0 0 6 6 6 4 Kelch motif DUF3342 PF11822.8 CDJ82584.1 - 0.0045 17.2 0.1 0.029 14.5 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3342) SNARE PF05739.19 CDJ82585.1 - 3.6e-15 55.7 3.1 9.1e-15 54.4 3.1 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 CDJ82585.1 - 6.3e-08 32.5 8.8 1.1e-07 31.7 8.8 1.4 1 0 0 1 1 1 1 Syntaxin DUF3675 PF12428.8 CDJ82585.1 - 0.069 13.7 0.4 0.069 13.7 0.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3675) MMPL PF03176.15 CDJ82585.1 - 0.13 11.2 0.1 0.26 10.2 0.1 1.5 1 0 0 1 1 1 0 MMPL family HeLo PF14479.6 CDJ82585.1 - 0.82 9.5 7.6 6.4 6.6 0.5 2.7 1 1 1 3 3 3 0 Prion-inhibition and propagation Med2 PF11214.8 CDJ82585.1 - 5 7.4 11.5 0.79 9.9 3.2 3.0 3 1 1 4 4 4 0 Mediator complex subunit 2 HATPase_c_3 PF13589.6 CDJ82586.1 - 7.1e-22 77.7 0.0 1e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDJ82586.1 - 0.00044 20.7 0.0 0.0007 20.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Morc6_S5 PF17942.1 CDJ82587.1 - 3.4e-24 85.5 4.4 4.6e-15 55.9 0.2 2.5 2 0 0 2 2 2 2 Morc6 ribosomal protein S5 domain 2-like zf-CW PF07496.15 CDJ82587.1 - 1.4e-11 44.2 4.2 3.7e-11 42.9 4.2 1.8 1 0 0 1 1 1 1 CW-type Zinc Finger PHD PF00628.29 CDJ82587.1 - 0.022 14.6 3.0 0.057 13.3 3.0 1.6 1 0 0 1 1 1 0 PHD-finger SnoaL PF07366.12 CDJ82587.1 - 0.14 12.0 0.0 6.1 6.7 0.0 2.3 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase FAD_binding_1 PF00667.20 CDJ82588.1 - 2.5e-67 226.7 0.0 3.8e-67 226.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CDJ82588.1 - 2.9e-34 118.3 0.2 5.4e-34 117.5 0.2 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CDJ82588.1 - 5e-18 65.7 0.0 1.9e-17 63.9 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain RPN1_RPN2_N PF17781.1 CDJ82589.1 - 1.2e-58 198.9 4.0 2.4e-58 198.0 4.0 1.5 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 CDJ82589.1 - 1.4e-31 108.2 0.1 3.5e-31 107.0 0.1 1.7 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 CDJ82589.1 - 2e-15 56.3 14.0 0.00017 21.9 0.1 7.8 7 0 0 7 7 7 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CDJ82589.1 - 0.00044 20.6 0.5 1.3 9.4 0.0 3.8 3 1 1 4 4 4 2 HEAT repeats THAP PF05485.12 CDJ82589.1 - 0.21 12.5 0.3 0.38 11.7 0.3 1.4 1 0 0 1 1 1 0 THAP domain EGF PF00008.27 CDJ82590.1 - 5.3e-39 132.1 132.3 2.1e-07 31.1 8.7 11.9 10 0 0 10 10 10 9 EGF-like domain Ephrin_rec_like PF07699.13 CDJ82590.1 - 2.5e-37 126.4 65.0 1.3e-11 44.0 8.1 7.1 5 1 1 6 6 6 4 Putative ephrin-receptor like hEGF PF12661.7 CDJ82590.1 - 9.4e-20 70.5 123.9 0.00043 20.8 3.2 13.0 12 1 1 13 13 13 8 Human growth factor-like EGF Laminin_G_3 PF13385.6 CDJ82590.1 - 9.4e-12 45.3 0.6 1.6e-11 44.5 0.6 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF_3 PF12947.7 CDJ82590.1 - 2.9e-10 40.2 121.0 3.4e-08 33.6 7.7 11.5 8 3 2 10 10 10 5 EGF domain EGF_2 PF07974.13 CDJ82590.1 - 7.8e-10 39.0 150.3 0.0098 16.2 12.7 12.0 9 2 2 11 11 11 9 EGF-like domain HYR PF02494.16 CDJ82590.1 - 4.2e-09 36.6 0.2 1.3e-08 35.0 0.2 1.9 1 0 0 1 1 1 1 HYR domain Pentaxin PF00354.17 CDJ82590.1 - 0.00015 21.5 0.1 0.0047 16.6 0.0 2.2 2 0 0 2 2 2 1 Pentaxin family EGF_CA PF07645.15 CDJ82590.1 - 0.00019 21.5 19.6 0.0014 18.8 5.7 14.7 7 4 8 15 15 15 4 Calcium-binding EGF domain cEGF PF12662.7 CDJ82590.1 - 0.0015 18.4 4.9 0.0015 18.4 4.9 13.2 15 1 1 16 16 16 5 Complement Clr-like EGF-like Claudin_2 PF13903.6 CDJ82591.1 - 1.1 8.9 10.8 1.9 8.2 10.6 1.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Sushi PF00084.20 CDJ82592.1 - 2.8e-35 120.7 38.0 5.2e-10 39.8 0.5 9.0 9 0 0 9 9 9 6 Sushi repeat (SCR repeat) Ephrin_rec_like PF07699.13 CDJ82592.1 - 7.6e-30 102.4 47.7 3.6e-12 45.8 5.9 5.7 4 1 1 5 5 5 3 Putative ephrin-receptor like EGF PF00008.27 CDJ82592.1 - 8.9e-24 83.4 62.7 8.5e-07 29.2 6.6 8.5 6 0 0 6 6 6 6 EGF-like domain HYR PF02494.16 CDJ82592.1 - 1.2e-18 67.2 3.3 3.3e-08 33.8 0.7 2.9 2 0 0 2 2 2 2 HYR domain EGF_CA PF07645.15 CDJ82592.1 - 8.8e-16 57.8 17.6 4.7e-10 39.5 3.1 9.7 10 3 2 12 12 12 5 Calcium-binding EGF domain F5_F8_type_C PF00754.25 CDJ82592.1 - 4e-14 52.8 0.0 7.7e-10 39.0 0.0 2.3 2 0 0 2 2 2 2 F5/8 type C domain hEGF PF12661.7 CDJ82592.1 - 1.7e-12 47.4 60.4 0.00021 21.8 2.0 9.1 8 0 0 8 8 8 5 Human growth factor-like EGF FXa_inhibition PF14670.6 CDJ82592.1 - 1.2e-07 31.9 5.8 1.2e-07 31.9 5.8 11.0 7 2 3 10 10 10 2 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 CDJ82592.1 - 0.01 16.0 60.8 0.035 14.3 6.1 7.9 7 0 0 7 7 7 0 EGF domain EGF_2 PF07974.13 CDJ82592.1 - 0.71 10.3 81.6 0.1 13.0 8.3 8.2 7 0 0 7 7 7 0 EGF-like domain CUB PF00431.20 CDJ82593.1 - 5.9e-34 116.7 0.0 7.5e-20 71.3 0.0 2.5 3 0 0 3 3 3 2 CUB domain Lectin_C PF00059.21 CDJ82593.1 - 1.7e-19 70.5 0.5 3.5e-19 69.5 0.1 1.8 2 0 0 2 2 2 1 Lectin C-type domain Ldl_recept_a PF00057.18 CDJ82593.1 - 7.7e-10 38.8 4.9 1.8e-09 37.6 4.9 1.7 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A CUB_2 PF02408.20 CDJ82593.1 - 4e-05 23.4 0.1 0.067 13.0 0.0 2.4 2 1 0 2 2 2 2 CUB-like domain UL45 PF05473.12 CDJ82593.1 - 0.00012 21.8 0.1 0.0002 21.1 0.1 1.3 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like MFS_1 PF07690.16 CDJ82595.1 - 5.4e-32 111.1 38.7 3.6e-24 85.3 27.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 CDJ82596.1 - 3.1e-09 36.2 3.8 5.1e-09 35.5 3.8 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1440 PF07274.12 CDJ82596.1 - 0.033 14.5 0.1 0.071 13.5 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1440) TMEM154 PF15102.6 CDJ82597.1 - 0.082 12.8 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF1679 PF07914.11 CDJ82598.1 - 6.3e-122 407.4 2.6 7.1e-122 407.2 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 CDJ82598.1 - 2.8e-19 69.5 0.7 5.2e-19 68.7 0.7 1.5 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 CDJ82598.1 - 7.4e-09 35.9 0.3 1.1e-08 35.3 0.3 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDJ82598.1 - 0.00025 20.7 0.6 0.00047 19.8 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase ACP_PD PF04336.12 CDJ82598.1 - 0.024 15.1 0.3 4.4 7.8 0.0 3.7 3 1 1 4 4 4 0 Acyl carrier protein phosphodiesterase Flavi_NS5 PF00972.20 CDJ82598.1 - 0.03 12.5 0.1 0.047 11.8 0.1 1.2 1 0 0 1 1 1 0 Flavivirus RNA-directed RNA polymerase DUF1679 PF07914.11 CDJ82599.1 - 2.1e-243 807.5 5.4 6.7e-125 417.2 3.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) EcKinase PF02958.20 CDJ82599.1 - 1.7e-39 135.9 4.0 5.6e-19 68.5 1.0 2.5 2 0 0 2 2 2 2 Ecdysteroid kinase APH PF01636.23 CDJ82599.1 - 9.7e-19 68.2 3.0 2.3e-08 34.3 0.1 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDJ82599.1 - 4.1e-08 33.1 0.5 0.002 17.7 0.0 2.9 3 0 0 3 3 3 2 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 CDJ82599.1 - 1.1e-05 24.8 2.1 0.11 11.7 0.0 3.5 4 0 0 4 4 4 2 Fructosamine kinase Kdo PF06293.14 CDJ82599.1 - 0.0004 19.8 1.0 1.1 8.6 0.0 3.0 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family SSPI PF14098.6 CDJ82599.1 - 0.015 15.5 0.3 1.6 9.0 0.0 3.0 3 0 0 3 3 3 0 Small, acid-soluble spore protein I Epiglycanin_C PF14654.6 CDJ82599.1 - 0.18 11.9 0.0 7.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Caskin-tail PF16632.5 CDJ82599.1 - 0.21 12.0 0.8 3.2 8.2 0.0 3.1 3 0 0 3 3 3 0 C-terminal region of Caskin DUF1679 PF07914.11 CDJ82600.1 - 1.3e-120 403.1 2.3 1.4e-120 402.9 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 CDJ82600.1 - 2.1e-21 76.5 0.6 4.6e-21 75.4 0.6 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 CDJ82600.1 - 4.9e-10 39.7 0.1 1.3e-09 38.4 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 CDJ82600.1 - 0.00029 20.1 0.7 0.011 14.9 0.0 2.1 2 0 0 2 2 2 1 Fructosamine kinase Choline_kinase PF01633.20 CDJ82600.1 - 0.0009 18.9 0.7 0.0056 16.3 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.14 CDJ82600.1 - 0.0037 16.6 0.8 0.1 12.0 0.1 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family SSPI PF14098.6 CDJ82600.1 - 0.018 15.2 0.2 0.07 13.3 0.0 2.2 2 0 0 2 2 2 0 Small, acid-soluble spore protein I Ret2_MD PF18528.1 CDJ82600.1 - 0.029 14.7 0.6 0.085 13.2 0.0 2.2 3 0 0 3 3 3 0 RNA editing 3' terminal uridylyl transferase 2 middle domain DUF1679 PF07914.11 CDJ82601.1 - 4.2e-121 404.7 1.4 4.8e-121 404.5 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 CDJ82601.1 - 1.8e-19 70.2 1.2 3.3e-19 69.3 1.2 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 CDJ82601.1 - 4.2e-11 43.2 0.0 6e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ82601.1 - 0.00046 19.6 0.1 0.49 9.7 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Fructosamin_kin PF03881.14 CDJ82601.1 - 0.0047 16.2 0.2 0.012 14.9 0.2 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 CDJ82601.1 - 0.0061 16.2 0.1 0.011 15.4 0.1 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase Gag_p30 PF02093.16 CDJ82601.1 - 0.087 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Gag P30 core shell protein DUF1679 PF07914.11 CDJ82602.1 - 8.7e-88 294.9 0.7 9.8e-88 294.8 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 CDJ82602.1 - 1.9e-18 66.8 0.5 5e-18 65.4 0.1 1.9 1 1 1 2 2 2 1 Ecdysteroid kinase APH PF01636.23 CDJ82602.1 - 2.2e-12 47.4 0.0 3.6e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDJ82602.1 - 0.0016 18.1 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase FliG_N PF14842.6 CDJ82602.1 - 0.071 13.7 0.3 11 6.6 0.1 2.9 3 0 0 3 3 3 0 FliG N-terminal domain Kdo PF06293.14 CDJ82602.1 - 0.086 12.2 0.0 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APOBEC_N PF08210.11 CDJ82603.1 - 7.4e-27 94.4 0.6 7.4e-27 94.4 0.6 2.4 2 1 0 3 3 3 1 APOBEC-like N-terminal domain STAS PF01740.21 CDJ82605.1 - 6.2e-07 29.1 0.0 6.6e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 CDJ82605.1 - 0.024 14.9 0.0 0.039 14.3 0.0 1.3 1 0 0 1 1 1 0 STAS domain Sulfate_transp PF00916.20 CDJ82606.1 - 2.1e-39 135.4 0.8 3.2e-39 134.8 0.8 1.3 1 0 0 1 1 1 1 Sulfate permease family RVT_1 PF00078.27 CDJ82607.1 - 1.5e-38 132.6 0.1 3.3e-38 131.4 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RING_5 PF14634.6 CDJ82609.1 - 1.8e-07 31.0 8.3 4.4e-07 29.7 8.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDJ82609.1 - 0.0002 21.1 6.7 0.00054 19.8 6.7 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CDJ82609.1 - 0.0051 16.8 5.2 0.018 15.0 5.2 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.5 CDJ82609.1 - 0.029 14.5 5.9 0.029 14.5 5.9 1.9 2 0 0 2 2 2 0 zinc RING finger of MSL2 Sipho_Gp157 PF05565.11 CDJ82609.1 - 0.038 14.0 2.5 0.066 13.2 2.5 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 Blt1 PF12754.7 CDJ82609.1 - 0.078 13.3 7.0 2.2 8.6 0.9 2.4 1 1 1 2 2 2 0 Blt1 N-terminal domain zf-RING_2 PF13639.6 CDJ82609.1 - 0.15 12.5 7.7 0.45 10.9 7.7 1.9 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 CDJ82609.1 - 0.2 11.6 10.8 0.047 13.6 6.9 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ82609.1 - 0.6 10.0 9.5 3.3 7.6 9.5 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ82609.1 - 9.9 6.4 9.2 44 4.4 9.3 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING IDO PF01231.18 CDJ82610.1 - 5.1e-82 276.0 2.1 1.6e-78 264.5 0.1 2.1 1 1 1 2 2 2 2 Indoleamine 2,3-dioxygenase APG6_N PF17675.1 CDJ82611.1 - 0.0099 16.4 9.0 0.0099 16.4 9.0 3.2 3 1 0 3 3 3 2 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 CDJ82611.1 - 0.32 11.1 13.3 0.22 11.6 3.0 3.0 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein CortBP2 PF09727.9 CDJ82611.1 - 0.58 10.0 16.6 0.037 13.9 10.2 2.2 1 1 0 2 2 2 0 Cortactin-binding protein-2 UPF0242 PF06785.11 CDJ82611.1 - 0.81 9.8 16.8 0.97 9.5 5.3 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 CDJ82611.1 - 3.4 7.5 15.5 6.8 6.5 0.0 3.9 3 1 1 4 4 4 0 Septum formation initiator Med6 PF04934.14 CDJ82612.1 - 5.4e-36 123.3 0.7 8.4e-36 122.7 0.7 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component UMP1 PF05348.11 CDJ82612.1 - 3.5e-06 27.2 0.1 0.00035 20.8 0.0 2.6 3 0 0 3 3 3 2 Proteasome maturation factor UMP1 Ribosomal_S26e PF01283.19 CDJ82613.1 - 0.016 15.7 0.1 0.033 14.6 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S26e Rap_GAP PF02145.15 CDJ82614.1 - 1.4e-66 223.6 0.0 2.2e-66 223.0 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP ADIP PF11559.8 CDJ82614.1 - 0.031 14.4 8.3 0.051 13.6 8.3 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.9 CDJ82614.1 - 0.37 9.8 9.6 0.57 9.2 9.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 7TM_GPCR_Str PF10326.9 CDJ82615.1 - 4.1e-32 111.8 11.3 4.9e-32 111.5 11.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srj PF10319.9 CDJ82615.1 - 7.2e-17 61.7 8.1 1.1e-16 61.1 8.1 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Srd PF10317.9 CDJ82615.1 - 1.9e-16 60.1 10.6 2.1e-16 60.0 10.6 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Srh PF10318.9 CDJ82615.1 - 1.9e-13 50.1 4.7 2.7e-13 49.7 4.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Sri PF10327.9 CDJ82615.1 - 0.0011 18.2 8.0 0.0025 17.1 8.0 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri DUF3087 PF11286.8 CDJ82615.1 - 0.014 14.8 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) UPAR_LY6_2 PF16975.5 CDJ82616.1 - 6e-06 26.4 8.0 8e-06 26.0 8.0 1.1 1 0 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 Activin_recp PF01064.23 CDJ82616.1 - 0.0026 18.8 10.9 0.0032 18.5 10.9 1.1 1 0 0 1 1 1 1 Activin types I and II receptor domain QVR PF17064.5 CDJ82616.1 - 0.019 15.2 9.3 0.04 14.1 9.3 1.6 1 1 0 1 1 1 0 Sleepless protein UPAR_LY6 PF00021.21 CDJ82616.1 - 0.029 15.1 8.3 0.041 14.6 8.3 1.2 1 0 0 1 1 1 0 u-PAR/Ly-6 domain Erythro-docking PF09277.11 CDJ82617.1 - 0.16 11.9 1.1 0.53 10.2 0.3 2.0 2 0 0 2 2 2 0 Erythronolide synthase, docking DUF1907 PF08925.11 CDJ82618.1 - 3.4e-88 295.7 0.0 4e-88 295.5 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) CCDC92 PF14916.6 CDJ82619.1 - 2.9e-07 30.1 0.2 2.9e-07 30.1 0.2 2.6 1 1 0 1 1 1 1 Coiled-coil domain of unknown function Med9 PF07544.13 CDJ82619.1 - 0.0014 18.6 14.9 0.015 15.4 4.0 2.7 1 1 1 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 Fmp27_WPPW PF10359.9 CDJ82619.1 - 0.0022 17.0 5.4 0.0022 17.0 5.4 2.0 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF812 PF05667.11 CDJ82619.1 - 0.0027 16.7 17.4 0.0034 16.3 17.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) MetOD2 PF18548.1 CDJ82619.1 - 0.013 15.5 11.2 0.19 11.8 2.2 2.9 1 1 1 2 2 2 0 Metanogen output domain 2 ZYG-11_interact PF05884.12 CDJ82619.1 - 0.017 14.6 2.3 0.027 13.9 2.3 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF4795 PF16043.5 CDJ82619.1 - 0.019 14.5 13.9 0.027 14.1 13.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) AAA_23 PF13476.6 CDJ82619.1 - 0.047 14.2 13.7 0.08 13.4 13.7 1.4 1 0 0 1 1 1 0 AAA domain HAD_2 PF13419.6 CDJ82619.1 - 0.11 12.5 2.6 0.28 11.2 0.5 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Baculo_PEP_C PF04513.12 CDJ82619.1 - 0.27 11.3 7.9 0.28 11.2 6.0 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 CDJ82619.1 - 0.5 10.7 3.1 24 5.3 3.3 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Golgin_A5 PF09787.9 CDJ82619.1 - 0.52 9.7 29.6 1 8.8 17.3 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 Tweety PF04906.13 CDJ82619.1 - 0.63 8.6 2.4 1.3 7.6 2.4 1.4 1 0 0 1 1 1 0 Tweety DUF3584 PF12128.8 CDJ82619.1 - 0.86 7.0 23.8 1.1 6.7 23.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 CDJ82619.1 - 0.89 9.6 8.9 2.3 8.3 7.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 CDJ82619.1 - 0.94 10.0 19.7 5.9 7.4 13.7 3.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF2203 PF09969.9 CDJ82619.1 - 1.1 10.0 17.4 1.2 9.9 0.6 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) TMF_DNA_bd PF12329.8 CDJ82619.1 - 1.2 9.1 22.2 0.75 9.8 16.4 3.1 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.7 CDJ82619.1 - 1.7 8.8 23.0 1.4 9.1 15.7 2.7 1 1 1 2 2 2 0 Tropomyosin like SlyX PF04102.12 CDJ82619.1 - 2.2 9.0 27.2 0.075 13.7 6.6 3.8 1 1 2 3 3 3 0 SlyX NPV_P10 PF05531.12 CDJ82619.1 - 2.7 8.5 7.3 72 3.9 7.0 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Macoilin PF09726.9 CDJ82619.1 - 2.8 6.4 17.9 3.9 5.9 17.9 1.1 1 0 0 1 1 1 0 Macoilin family eIF3_N PF09440.10 CDJ82619.1 - 4 7.9 8.4 0.98 9.9 4.2 1.9 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain Fib_alpha PF08702.10 CDJ82619.1 - 4.7 7.4 23.2 4.7 7.4 3.9 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family GBP_C PF02841.14 CDJ82619.1 - 4.9 6.5 19.8 2.8 7.2 8.1 2.1 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain COG2 PF06148.11 CDJ82619.1 - 7.4 6.7 10.0 18 5.4 8.8 2.3 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 HAP1_N PF04849.13 CDJ82619.1 - 9.4 5.3 25.6 0.031 13.5 2.7 2.6 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Shisa PF13908.6 CDJ82621.1 - 0.021 15.1 0.3 0.021 15.1 0.3 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4448 PF14610.6 CDJ82621.1 - 0.045 13.5 0.0 0.045 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Stevor PF17410.2 CDJ82621.1 - 0.057 13.0 0.6 0.057 13.0 0.6 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DAG1 PF05454.11 CDJ82621.1 - 0.062 12.7 1.0 0.068 12.5 1.0 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF4690 PF15756.5 CDJ82621.1 - 0.15 12.7 0.0 0.16 12.6 0.0 1.1 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DUF2207 PF09972.9 CDJ82621.1 - 0.16 10.7 0.1 0.16 10.7 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Synaptobrevin PF00957.21 CDJ82621.1 - 0.56 10.0 3.5 0.76 9.6 3.5 1.3 1 0 0 1 1 1 0 Synaptobrevin EphA2_TM PF14575.6 CDJ82621.1 - 1.3 9.9 3.2 2.1 9.3 3.2 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain HemY_N PF07219.13 CDJ82621.1 - 1.6 9.0 6.3 12 6.1 5.8 2.0 1 1 1 2 2 2 0 HemY protein N-terminus Tetraspanin PF00335.20 CDJ82622.1 - 1.6e-22 80.4 3.4 2.1e-22 80.0 3.4 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF3671 PF12420.8 CDJ82622.1 - 0.12 12.4 1.0 0.27 11.3 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF4131 PF13567.6 CDJ82622.1 - 0.39 10.3 6.1 2.9 7.5 6.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Phage_holin_3_6 PF07332.11 CDJ82622.1 - 4.2 7.4 16.4 0.032 14.3 3.7 2.4 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Exo_endo_phos PF03372.23 CDJ82624.1 - 3.5e-10 39.8 0.0 7e-10 38.8 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CDJ82624.1 - 5.5e-09 35.9 0.2 1.2e-08 34.8 0.2 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase WD40 PF00400.32 CDJ82626.1 - 7.4e-05 23.4 0.2 0.014 16.3 0.0 2.9 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ82626.1 - 0.096 13.0 0.0 5 7.5 0.0 2.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain UDPGT PF00201.18 CDJ82627.1 - 1.2e-47 162.9 0.0 1.3e-47 162.7 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ82627.1 - 1.2e-10 41.6 0.0 3e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 CDJ82627.1 - 0.016 14.5 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 UDPGT PF00201.18 CDJ82628.1 - 2.1e-49 168.6 0.0 2.6e-49 168.4 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ82628.1 - 4e-10 39.9 0.0 6.7e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 CDJ82628.1 - 0.026 13.8 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF5533 PF17685.1 CDJ82628.1 - 0.8 10.1 4.5 0.41 11.0 1.5 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5533) Pkinase PF00069.25 CDJ82630.1 - 6.6e-24 84.7 0.4 7.8e-24 84.5 0.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ82630.1 - 1.9e-14 53.6 0.1 2.4e-14 53.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ82630.1 - 2.8e-05 24.2 0.0 0.0037 17.2 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ82630.1 - 7.5e-05 21.7 0.0 0.00013 20.9 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Dicer_dimer PF03368.14 CDJ82630.1 - 0.14 12.4 0.0 0.68 10.1 0.0 2.2 2 0 0 2 2 2 0 Dicer dimerisation domain UDPGT PF00201.18 CDJ82633.1 - 4.9e-41 141.1 0.0 6.7e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ82633.1 - 3.9e-11 43.2 0.0 6.9e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 CDJ82633.1 - 0.0058 15.9 0.0 0.0092 15.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 Fip1 PF05182.13 CDJ82634.1 - 5e-25 86.7 1.5 9e-25 85.9 1.5 1.4 1 0 0 1 1 1 1 Fip1 motif EAP30 PF04157.16 CDJ82635.1 - 7.8e-36 123.5 0.4 1.1e-35 123.1 0.4 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 CDJ82635.1 - 3.4e-20 72.0 0.0 6.7e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 ORF6N PF10543.9 CDJ82635.1 - 0.085 13.1 0.0 0.31 11.3 0.1 1.8 2 0 0 2 2 2 0 ORF6N domain CN_hydrolase PF00795.22 CDJ82636.1 - 7.1e-62 209.1 0.0 8.6e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase THF_DHG_CYH_C PF02882.19 CDJ82637.1 - 6e-64 214.2 0.0 8.1e-64 213.8 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CDJ82637.1 - 2e-31 108.6 1.1 3.4e-31 107.9 1.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain CN_hydrolase PF00795.22 CDJ82638.1 - 6.1e-64 215.9 0.0 7.4e-64 215.6 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase tRNA_m1G_MT PF01746.21 CDJ82640.1 - 0.0013 18.5 0.0 0.022 14.5 0.0 2.4 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase MFS_1 PF07690.16 CDJ82641.1 - 2.2e-44 151.8 34.8 6.9e-44 150.2 30.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Rubella_Capsid PF05750.11 CDJ82641.1 - 7.1 6.1 9.5 2.8 7.5 6.5 1.6 1 1 1 2 2 2 0 Rubella capsid protein GILT PF03227.16 CDJ82643.1 - 1.6e-26 92.6 1.4 2.5e-26 92.0 1.4 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) PAP2 PF01569.21 CDJ82644.1 - 9.7e-16 57.8 7.1 2e-15 56.7 7.1 1.5 1 0 0 1 1 1 1 PAP2 superfamily Colicin_V PF02674.16 CDJ82644.1 - 0.03 14.3 2.9 0.066 13.2 0.3 2.2 2 0 0 2 2 2 0 Colicin V production protein BioY PF02632.14 CDJ82644.1 - 0.57 10.3 5.9 0.23 11.5 0.5 2.3 2 0 0 2 2 2 0 BioY family DUF4199 PF13858.6 CDJ82644.1 - 6.8 7.1 9.8 0.18 12.2 2.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) RRM_1 PF00076.22 CDJ82645.1 - 2.7e-15 55.9 0.1 1.2e-14 53.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CDJ82646.1 - 2.1e-15 56.3 0.5 3.1e-15 55.7 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Jacalin PF01419.17 CDJ82646.1 - 0.044 13.7 0.1 0.41 10.6 0.0 2.3 2 1 0 2 2 2 0 Jacalin-like lectin domain Peptidase_M3 PF01432.20 CDJ82647.1 - 5.1e-77 260.1 0.0 7.4e-77 259.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 CDJ82647.1 - 0.22 11.8 0.7 0.54 10.5 0.0 2.0 3 0 0 3 3 3 0 Effector protein DSPc PF00782.20 CDJ82648.1 - 9.5e-23 80.5 0.0 1.5e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDJ82648.1 - 0.00054 19.6 0.1 0.0008 19.0 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase zinc_ribbon_5 PF13719.6 CDJ82648.1 - 0.0041 16.8 0.7 0.0041 16.8 0.7 2.4 2 0 0 2 2 2 1 zinc-ribbon domain PE-PPE PF08237.11 CDJ82648.1 - 0.036 13.6 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain zinc_ribbon_4 PF13717.6 CDJ82648.1 - 0.073 13.0 4.4 1.9 8.5 0.6 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_12 PF11331.8 CDJ82648.1 - 0.15 11.9 2.0 0.68 9.8 0.4 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain Condensation PF00668.20 CDJ82649.1 - 3.4e-51 174.4 0.0 1.5e-50 172.2 0.0 1.8 1 1 0 1 1 1 1 Condensation domain AMP-binding PF00501.28 CDJ82649.1 - 6.8e-50 169.9 0.0 1e-49 169.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 CDJ82649.1 - 0.0022 18.3 0.0 0.0082 16.5 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site S_100 PF01023.19 CDJ82649.1 - 0.14 11.9 0.1 0.93 9.2 0.0 2.4 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain Condensation PF00668.20 CDJ82650.1 - 7.9e-104 347.9 1.7 2e-42 145.4 0.0 5.1 3 2 0 3 3 3 3 Condensation domain AMP-binding PF00501.28 CDJ82650.1 - 9.3e-104 347.3 0.0 5.5e-52 176.8 0.1 3.1 2 1 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 CDJ82650.1 - 3.9e-25 88.0 1.7 8.8e-11 42.0 0.0 3.6 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 CDJ82650.1 - 2.8e-12 47.4 0.0 2.9e-08 34.6 0.1 2.7 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain BAAT_C PF08840.11 CDJ82650.1 - 0.0044 17.0 0.0 0.018 15.0 0.0 1.9 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Transferase PF02458.15 CDJ82650.1 - 0.041 12.6 0.0 0.4 9.3 0.0 2.2 2 0 0 2 2 2 0 Transferase family Lustrin_cystein PF14625.6 CDJ82651.1 - 0.034 14.5 0.1 0.056 13.8 0.1 1.2 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain RE_Bpu10I PF09549.10 CDJ82651.1 - 0.12 11.9 0.2 0.15 11.6 0.2 1.1 1 0 0 1 1 1 0 Bpu10I restriction endonuclease SCVP PF17619.2 CDJ82652.1 - 6.4e-37 126.3 4.4 5.5e-19 68.8 0.2 2.2 2 0 0 2 2 2 2 Secreted clade V proteins SCVP PF17619.2 CDJ82653.1 - 2.4e-39 134.1 5.7 3.3e-22 79.1 1.3 2.1 2 0 0 2 2 2 2 Secreted clade V proteins DUF866 PF05907.13 CDJ82653.1 - 0.0015 18.5 0.2 0.6 10.0 0.1 2.4 2 1 0 2 2 2 2 Eukaryotic protein of unknown function (DUF866) Glyco_hydro_2_N PF02837.18 CDJ82653.1 - 0.041 13.8 0.4 3.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, sugar binding domain Membr_traf_MHD PF10540.9 CDJ82653.1 - 0.089 13.0 0.1 15 5.7 0.0 2.1 2 0 0 2 2 2 0 Munc13 (mammalian uncoordinated) homology domain DUF2341 PF10102.9 CDJ82653.1 - 0.09 13.4 1.8 12 6.6 0.4 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2341) HTH_35 PF13693.6 CDJ82657.1 - 0.0032 17.5 0.4 0.48 10.5 0.1 2.6 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding DDR PF08841.10 CDJ82657.1 - 0.067 12.2 0.0 0.086 11.8 0.0 1.1 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain 7TM_GPCR_Srv PF10323.9 CDJ82658.1 - 1.2e-09 38.0 11.0 1.3e-09 37.8 11.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Srg PF02118.21 CDJ82658.1 - 3.7e-07 30.1 12.1 4.2e-07 29.9 12.1 1.0 1 0 0 1 1 1 1 Srg family chemoreceptor 7TM_GPCR_Srx PF10328.9 CDJ82659.1 - 5.3e-06 26.3 0.9 6.2e-06 26.0 0.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 CDJ82659.1 - 8e-06 25.4 0.6 8.9e-06 25.3 0.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Srg PF02118.21 CDJ82659.1 - 1.4e-05 24.9 2.4 1.6e-05 24.7 2.4 1.1 1 0 0 1 1 1 1 Srg family chemoreceptor 7tm_1 PF00001.21 CDJ82659.1 - 0.0054 16.1 1.3 0.0059 16.0 1.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Tctex-1 PF03645.13 CDJ82659.1 - 0.06 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Tctex-1 family 7TM_GPCR_Srv PF10323.9 CDJ82660.1 - 3.1e-10 39.9 5.8 3.6e-10 39.7 5.8 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Srg PF02118.21 CDJ82660.1 - 3e-09 37.0 6.0 3.5e-09 36.7 6.0 1.1 1 0 0 1 1 1 1 Srg family chemoreceptor Srg PF02118.21 CDJ82661.1 - 0.00025 20.8 5.8 0.00029 20.6 5.8 1.1 1 0 0 1 1 1 1 Srg family chemoreceptor 7TM_GPCR_Srx PF10328.9 CDJ82661.1 - 0.00098 18.8 6.4 0.0012 18.5 6.2 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 CDJ82661.1 - 0.057 12.7 2.4 0.062 12.6 2.4 1.2 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Keratin_2_head PF16208.5 CDJ82662.1 - 1.4 9.0 20.5 1.7 8.8 20.5 1.1 1 0 0 1 1 1 0 Keratin type II head 7TM_GPCR_Srv PF10323.9 CDJ82663.1 - 3e-20 72.7 10.0 3.5e-20 72.5 10.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Claudin_3 PF06653.11 CDJ82663.1 - 0.2 11.6 10.2 0.22 11.4 8.7 1.8 1 1 1 2 2 2 0 Tight junction protein, Claudin-like MTTB PF06253.11 CDJ82664.1 - 0.0076 14.3 0.0 0.0081 14.2 0.0 1.0 1 0 0 1 1 1 1 Trimethylamine methyltransferase (MTTB) SSP160 PF06933.11 CDJ82664.1 - 0.054 11.7 1.3 0.057 11.6 1.3 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RVT_1 PF00078.27 CDJ82669.1 - 1.7e-37 129.1 0.0 3.4e-37 128.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDJ82670.1 - 1.5e-09 37.7 0.3 0.00012 21.8 0.0 3.0 3 1 0 3 3 3 2 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ82670.1 - 1.6e-05 24.5 0.0 0.0049 16.4 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Rpn9_C PF18261.1 CDJ82670.1 - 0.0018 17.8 0.4 2.8 7.6 0.1 2.7 2 0 0 2 2 2 2 Rpn9 C-terminal helix tRNA-synt_1b PF00579.25 CDJ82670.1 - 0.012 15.0 0.0 3 7.1 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) EFG_II PF14492.6 CDJ82670.1 - 0.054 13.6 0.0 16 5.7 0.0 2.5 2 0 0 2 2 2 0 Elongation Factor G, domain II PDEase_I PF00233.19 CDJ82671.1 - 5.4e-74 248.9 3.4 5.6e-74 248.9 1.2 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 CDJ82671.1 - 1.3e-12 48.5 0.0 2.6e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 CDJ82671.1 - 5.3e-09 36.5 0.0 1.3e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 CDJ82671.1 - 6.5e-07 29.8 0.0 2e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 GAF domain HD PF01966.22 CDJ82671.1 - 0.096 12.9 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 HD domain FGGY_N PF00370.21 CDJ82672.1 - 3.4e-19 69.4 0.0 9.4e-12 45.0 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Pkinase PF00069.25 CDJ82673.1 - 6.6e-10 38.8 0.0 7.8e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ82673.1 - 0.00017 21.0 0.0 0.00021 20.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase BAF250_C PF12031.8 CDJ82674.1 - 2.6e-88 295.6 0.2 2.6e-88 295.6 0.2 3.0 2 1 0 2 2 2 1 SWI/SNF-like complex subunit BAF250/Osa Mem_trans PF03547.18 CDJ82674.1 - 2.7 6.3 6.8 0.07 11.5 0.3 1.7 2 0 0 2 2 2 0 Membrane transport protein PAT1 PF09770.9 CDJ82674.1 - 5.1 5.2 72.5 11 4.2 72.5 1.5 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 V_ATPase_I PF01496.19 CDJ82674.1 - 7.5 4.3 42.3 14 3.4 42.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NTP_transf_6 PF06042.11 CDJ82675.1 - 0.0016 18.3 0.8 0.0018 18.1 0.8 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase Inhibitor_I10 PF12559.8 CDJ82675.1 - 0.0043 17.3 0.1 0.0059 16.8 0.1 1.2 1 0 0 1 1 1 1 Serine endopeptidase inhibitors DDA1 PF10172.9 CDJ82675.1 - 0.12 12.6 0.2 0.12 12.6 0.2 1.7 2 1 0 2 2 2 0 Det1 complexing ubiquitin ligase Collagen PF01391.18 CDJ82676.1 - 2.5e-24 84.8 82.2 7.7e-09 35.2 27.5 4.2 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ82676.1 - 1.4e-10 41.1 2.3 2.1e-10 40.5 2.3 1.3 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ82677.1 - 8.6e-27 92.7 86.9 2.3e-11 43.3 32.5 3.9 2 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) DUF4710 PF15828.5 CDJ82678.1 - 0.056 13.6 3.7 0.12 12.6 3.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) CRAL_TRIO PF00650.20 CDJ82679.1 - 6.4e-16 58.5 0.1 9.6e-16 57.9 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CDJ82679.1 - 0.0019 18.3 0.0 0.0033 17.6 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Alpha_adaptinC2 PF02883.20 CDJ82680.1 - 0.022 15.1 0.1 0.054 13.8 0.1 1.6 1 0 0 1 1 1 0 Adaptin C-terminal domain 7TM_GPCR_Srab PF10292.9 CDJ82681.1 - 1e-61 208.7 18.2 1.1e-61 208.5 18.2 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Srb PF02175.16 CDJ82681.1 - 4.6e-07 29.9 10.1 7e-07 29.3 10.1 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srb 7TM_GPCR_Sra PF02117.16 CDJ82681.1 - 3.1e-05 23.0 16.6 3.8e-05 22.7 16.6 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sra 7tm_1 PF00001.21 CDJ82681.1 - 0.00042 19.7 10.5 0.00057 19.3 10.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) COX2_TM PF02790.15 CDJ82681.1 - 0.031 14.4 1.8 0.031 14.4 1.8 2.4 2 1 2 4 4 4 0 Cytochrome C oxidase subunit II, transmembrane domain RVT_1 PF00078.27 CDJ82682.1 - 1.4e-13 50.9 0.1 2e-13 50.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PfkB PF00294.24 CDJ82683.1 - 3.5e-71 240.0 0.2 6.8e-71 239.0 0.2 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase CBFD_NFYB_HMF PF00808.23 CDJ82683.1 - 8.3e-25 86.9 0.9 1.5e-24 86.1 0.9 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDJ82683.1 - 0.0006 20.2 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF2724 PF10893.8 CDJ82683.1 - 0.22 11.4 0.0 0.44 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) Gln-synt_C PF00120.24 CDJ82684.1 - 8.9e-18 64.4 0.0 1.3e-13 50.6 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 CDJ82684.1 - 7.4e-13 48.0 0.0 1.5e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain SWIB PF02201.18 CDJ82685.1 - 0.0055 16.6 0.1 0.0082 16.0 0.1 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain UvrD_C PF13361.6 CDJ82685.1 - 0.048 13.0 0.1 0.051 12.9 0.1 1.0 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain 7tm_1 PF00001.21 CDJ82687.1 - 1.5e-37 129.4 9.4 1.5e-37 129.4 9.4 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 CDJ82687.1 - 8.6e-11 42.1 4.4 4e-10 39.9 4.4 1.9 1 1 0 1 1 1 1 Olfactory receptor Git3 PF11710.8 CDJ82687.1 - 0.00046 20.0 4.5 0.00093 19.0 4.5 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 DUF4179 PF13786.6 CDJ82687.1 - 1 9.9 0.0 1 9.9 0.0 2.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4179) zf-CCHC PF00098.23 CDJ82688.1 - 9e-07 28.7 0.8 1.7e-06 27.9 0.8 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 CDJ82688.1 - 0.0013 19.0 0.0 0.006 16.8 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein PNMA PF14893.6 CDJ82688.1 - 0.0022 17.4 0.4 0.0041 16.6 0.4 1.4 1 0 0 1 1 1 1 PNMA zf-CCHC_6 PF15288.6 CDJ82688.1 - 0.0055 16.5 1.4 0.013 15.4 1.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ82688.1 - 0.0088 15.8 0.7 0.019 14.7 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle SCAN PF02023.17 CDJ82688.1 - 0.063 13.1 0.1 0.19 11.6 0.1 1.8 1 0 0 1 1 1 0 SCAN domain Gag_p24 PF00607.20 CDJ82688.1 - 0.16 11.8 0.2 6.4 6.6 0.0 2.6 3 0 0 3 3 3 0 gag gene protein p24 (core nucleocapsid protein) Arc_C PF18162.1 CDJ82688.1 - 0.17 11.7 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Arc C-lobe CENP-H PF05837.12 CDJ82688.1 - 1.5 9.3 4.0 0.43 11.0 0.2 2.1 3 0 0 3 3 3 0 Centromere protein H (CENP-H) AAA_12 PF13087.6 CDJ82689.1 - 1.9e-37 128.8 0.0 2.5e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CDJ82689.1 - 2.6e-05 24.1 0.0 0.00012 22.0 0.0 1.9 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 CDJ82689.1 - 5.2e-05 23.0 0.1 0.00017 21.4 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 CDJ82689.1 - 0.013 15.3 0.0 0.027 14.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CDJ82689.1 - 0.021 14.6 0.0 0.07 12.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain UvrD_C PF13361.6 CDJ82689.1 - 0.093 12.1 0.0 2.1 7.6 0.0 1.9 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain Pro_isomerase PF00160.21 CDJ82690.1 - 1.4e-48 165.1 0.0 1.6e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Y_phosphatase PF00102.27 CDJ82691.1 - 2.5e-60 204.0 0.0 2.5e-60 204.0 0.0 1.4 2 0 0 2 2 2 1 Protein-tyrosine phosphatase UPF0254 PF06787.11 CDJ82691.1 - 0.0059 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0254) Peptidase_M10 PF00413.24 CDJ82693.1 - 6e-26 91.2 0.0 1e-25 90.4 0.0 1.4 1 0 0 1 1 1 1 Matrixin DUF4953 PF16313.5 CDJ82693.1 - 2e-05 23.9 0.1 4.2e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Met-zincin PG_binding_1 PF01471.18 CDJ82693.1 - 5.1e-05 23.4 0.0 0.00011 22.3 0.0 1.7 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Reprolysin_3 PF13582.6 CDJ82693.1 - 0.00088 19.8 0.0 0.0023 18.5 0.0 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 CDJ82693.1 - 0.012 15.2 1.6 3.7 7.1 0.3 2.3 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.6 CDJ82693.1 - 0.017 15.3 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Metallopep PF12044.8 CDJ82693.1 - 0.034 12.8 0.7 0.059 12.0 0.7 1.3 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M66 PF10462.9 CDJ82693.1 - 0.058 12.3 0.3 0.1 11.5 0.3 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_4 PF13583.6 CDJ82693.1 - 0.072 12.7 0.2 0.12 12.0 0.2 1.4 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 CDJ82693.1 - 0.11 12.4 0.1 0.29 11.1 0.1 1.6 2 0 0 2 2 2 0 Peptidase family M54 4HBT_3 PF13622.6 CDJ82694.1 - 4.2e-54 184.4 1.1 4.7e-54 184.2 0.5 1.4 2 0 0 2 2 2 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 CDJ82694.1 - 7e-18 64.8 0.2 9.9e-13 48.1 0.0 2.9 2 1 0 2 2 2 2 Acyl-CoA thioesterase YcbB PF08664.10 CDJ82694.1 - 0.079 13.0 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 YcbB domain zf-H2C2_2 PF13465.6 CDJ82695.1 - 1.5e-05 25.2 4.0 1.5e-05 25.2 4.0 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDJ82695.1 - 0.035 14.9 14.1 0.22 12.5 2.0 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 CDJ82695.1 - 0.058 13.8 7.9 0.93 10.0 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CDJ82695.1 - 0.066 13.7 1.7 0.066 13.7 1.7 3.9 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 CDJ82695.1 - 0.26 11.6 8.9 0.44 10.9 5.1 3.0 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 CDJ82695.1 - 0.29 11.0 5.0 0.13 12.1 1.1 2.5 2 1 0 2 2 2 0 Rad50 zinc hook motif zf-BED PF02892.15 CDJ82695.1 - 0.43 10.6 6.8 3 7.9 6.8 2.2 1 1 0 1 1 1 0 BED zinc finger P4Ha_N PF08336.11 CDJ82696.1 - 1.2e-33 116.0 1.4 2.5e-33 115.0 1.4 1.6 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 CDJ82696.1 - 7e-13 49.3 0.3 1.3e-12 48.4 0.3 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ANAPC3 PF12895.7 CDJ82696.1 - 0.0047 17.1 0.4 0.11 12.8 0.0 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CDJ82696.1 - 0.11 12.6 0.4 1.4 9.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Rnk_N PF14760.6 CDJ82696.1 - 0.14 12.7 0.5 0.58 10.7 0.0 2.3 2 0 0 2 2 2 0 Rnk N-terminus P4Ha_N PF08336.11 CDJ82697.1 - 7.3e-33 113.4 0.7 1.4e-32 112.5 0.7 1.5 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 CDJ82697.1 - 4.5e-16 59.5 0.2 8.2e-16 58.7 0.2 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 CDJ82697.1 - 8.9e-10 39.0 0.0 2e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 CDJ82697.1 - 4.3e-05 23.3 0.4 0.00053 19.9 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ82697.1 - 0.0077 16.3 0.1 0.02 14.9 0.1 1.7 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_MalT PF17874.1 CDJ82697.1 - 0.19 11.1 0.0 0.43 9.9 0.0 1.5 2 0 0 2 2 2 0 MalT-like TPR region Ldh_1_C PF02866.18 CDJ82700.1 - 1.4e-48 165.0 0.4 2.4e-48 164.3 0.4 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CDJ82700.1 - 1.1e-44 152.0 1.7 1.8e-44 151.2 1.7 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 CDJ82700.1 - 0.00019 20.8 2.5 0.00067 19.0 0.4 2.7 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.24 CDJ82700.1 - 0.15 12.5 0.8 0.99 9.9 0.1 2.5 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain MRP-S31 PF15433.6 CDJ82701.1 - 1e-62 212.6 2.0 1.5e-62 212.1 2.0 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 CAF1 PF04857.20 CDJ82703.1 - 5.3e-54 183.5 0.0 7.7e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease KH_8 PF17903.1 CDJ82704.1 - 9.3e-31 105.8 0.0 1.8e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain Aldedh PF00171.22 CDJ82705.1 - 1.9e-133 445.4 0.1 2.2e-133 445.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1_like PF12832.7 CDJ82706.1 - 7.9e-81 271.8 15.9 1e-80 271.5 15.9 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 CDJ82706.1 - 2.5e-21 76.0 35.5 5e-12 45.4 20.1 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.16 CDJ82706.1 - 7.6e-12 44.9 24.6 1.1e-09 37.9 6.3 3.3 4 0 0 4 4 4 3 Nucleoside H+ symporter LacY_symp PF01306.19 CDJ82706.1 - 0.00029 19.7 18.1 0.0093 14.8 0.0 3.2 3 0 0 3 3 3 2 LacY proton/sugar symporter MFS_2 PF13347.6 CDJ82706.1 - 0.001 17.7 31.9 0.0067 15.0 5.9 3.9 4 0 0 4 4 4 3 MFS/sugar transport protein CPP1-like PF11833.8 CDJ82706.1 - 0.071 12.8 0.1 0.83 9.3 0.0 2.6 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like MFS_3 PF05977.13 CDJ82706.1 - 0.31 9.4 16.7 0.084 11.3 8.6 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector DUF3572 PF12096.8 CDJ82707.1 - 0.0093 16.1 0.0 4.5 7.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3572) Adaptin_N PF01602.20 CDJ82709.1 - 1.6e-142 475.7 12.2 2e-142 475.5 12.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CDJ82709.1 - 4.6e-16 59.3 1.2 3.3e-11 43.5 0.0 3.8 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 CDJ82709.1 - 6.2e-07 29.6 4.7 0.041 14.1 0.0 4.3 4 0 0 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 CDJ82709.1 - 1.1e-05 25.7 0.0 1.3 9.4 0.0 4.5 3 1 1 4 4 4 1 HEAT repeats HEAT PF02985.22 CDJ82709.1 - 5e-05 23.2 1.9 3.2 8.2 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat RasGEF_N_2 PF14663.6 CDJ82709.1 - 0.0097 16.3 0.1 1.7 9.1 0.1 3.2 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Vac14_Fab1_bd PF12755.7 CDJ82709.1 - 0.025 15.2 0.2 0.55 10.9 0.1 3.3 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region HLH PF00010.26 CDJ82710.1 - 4.3e-17 61.8 2.0 4.3e-17 61.8 0.9 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain LIM PF00412.22 CDJ82711.1 - 9.2e-05 22.6 1.2 0.00013 22.1 1.2 1.2 1 0 0 1 1 1 1 LIM domain HemY_N PF07219.13 CDJ82712.1 - 0.034 14.3 0.0 0.078 13.2 0.0 1.6 1 0 0 1 1 1 0 HemY protein N-terminus Peptidase_M28 PF04389.17 CDJ82714.1 - 7e-45 153.2 0.0 8.6e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CDJ82714.1 - 8.8e-06 25.6 0.0 1.6e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 CDJ82714.1 - 0.0008 18.5 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase RVT_1 PF00078.27 CDJ82715.1 - 1.1e-36 126.4 0.0 1.8e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HSP70 PF00012.20 CDJ82716.1 - 1.1e-78 264.9 0.1 1.1e-78 264.9 0.1 4.2 2 1 2 4 4 4 1 Hsp70 protein GAIN PF16489.5 CDJ82716.1 - 0.0038 16.7 0.5 0.015 14.7 0.1 2.1 2 0 0 2 2 2 1 GPCR-Autoproteolysis INducing (GAIN) domain DUF727 PF05303.12 CDJ82717.1 - 5.8e-35 119.5 0.0 8.3e-35 119.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF727) DUF730 PF05325.11 CDJ82718.1 - 0.03 14.3 1.8 0.33 11.0 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF730) COX7a PF02238.15 CDJ82718.1 - 0.045 14.1 1.3 2.5 8.6 0.3 2.6 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII Cadherin PF00028.17 CDJ82719.1 - 1.1e-19 70.7 1.5 2e-12 47.4 0.0 5.4 4 1 2 6 6 6 2 Cadherin domain Cadherin_3 PF16184.5 CDJ82719.1 - 1.8e-07 31.2 0.1 0.022 14.8 0.0 2.8 2 0 0 2 2 2 2 Cadherin-like Sre PF03125.18 CDJ82720.1 - 4.6e-10 39.2 0.3 0.00011 21.6 0.0 2.1 2 0 0 2 2 2 2 C. elegans Sre G protein-coupled chemoreceptor 7TM_GPCR_Srab PF10292.9 CDJ82720.1 - 4.8e-10 38.9 2.1 2.8e-08 33.1 0.2 2.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Sra PF02117.16 CDJ82720.1 - 0.0069 15.3 0.2 0.017 14.0 0.0 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sra SCHIP-1 PF10148.9 CDJ82721.1 - 4.1e-18 65.8 10.7 7.2e-16 58.5 10.7 2.0 1 1 0 1 1 1 1 Schwannomin-interacting protein 1 EURL PF06937.11 CDJ82721.1 - 0.0088 15.5 0.6 0.011 15.2 0.6 1.1 1 0 0 1 1 1 1 EURL protein FEZ PF07763.13 CDJ82721.1 - 0.009 15.8 1.4 0.009 15.8 1.4 1.5 1 1 0 1 1 1 1 FEZ-like protein CAP PF00188.26 CDJ82722.1 - 1.4e-06 29.2 0.2 2.2e-06 28.5 0.2 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ADK PF00406.22 CDJ82723.1 - 3.9e-160 527.0 3.8 2e-52 177.3 0.1 3.1 3 0 0 3 3 3 3 Adenylate kinase AAA_17 PF13207.6 CDJ82723.1 - 2.9e-109 361.3 8.1 1.7e-35 122.4 0.3 3.2 3 0 0 3 3 3 3 AAA domain AAA_33 PF13671.6 CDJ82723.1 - 1.5e-22 80.3 0.0 1.3e-06 28.7 0.0 3.7 3 1 0 3 3 3 3 AAA domain AAA_18 PF13238.6 CDJ82723.1 - 1e-21 77.8 0.3 2.1e-05 25.1 0.0 3.5 3 0 0 3 3 3 3 AAA domain Zeta_toxin PF06414.12 CDJ82723.1 - 5.5e-12 45.4 0.0 0.018 14.3 0.0 3.2 3 0 0 3 3 3 3 Zeta toxin Thymidylate_kin PF02223.17 CDJ82723.1 - 2.2e-09 37.3 17.1 0.23 11.1 0.5 6.1 6 0 0 6 6 6 4 Thymidylate kinase Ploopntkinase3 PF18751.1 CDJ82723.1 - 1.2e-06 28.6 0.1 1.2 9.0 0.0 3.4 3 0 0 3 3 3 3 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 CDJ82723.1 - 9.4e-06 26.0 8.1 0.97 9.8 0.1 4.3 5 0 0 5 5 4 3 AAA domain AAA_28 PF13521.6 CDJ82723.1 - 0.00011 22.5 0.0 2.9 8.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain Hex_IIIa PF02455.16 CDJ82723.1 - 0.00019 20.4 0.3 0.16 10.8 0.0 3.0 3 0 0 3 3 3 1 Hexon-associated protein (IIIa) NTPase_1 PF03266.15 CDJ82723.1 - 0.00055 19.9 9.4 2.5 8.0 0.1 4.9 4 3 2 6 6 5 2 NTPase dNK PF01712.19 CDJ82723.1 - 0.00062 19.7 3.5 5.5 6.8 0.1 3.6 3 0 0 3 3 3 0 Deoxynucleoside kinase SRP54 PF00448.22 CDJ82723.1 - 0.00066 19.4 1.0 8.1 6.0 0.0 4.0 3 1 0 3 3 3 0 SRP54-type protein, GTPase domain Cytidylate_kin PF02224.18 CDJ82723.1 - 0.00078 19.2 9.1 3.1 7.5 0.0 4.6 5 0 0 5 5 5 3 Cytidylate kinase AAA_22 PF13401.6 CDJ82723.1 - 0.00095 19.4 1.7 13 6.1 0.1 4.0 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 CDJ82723.1 - 0.013 14.7 1.5 14 4.8 0.0 3.3 3 0 0 3 3 3 0 NB-ARC domain TrwB_AAD_bind PF10412.9 CDJ82723.1 - 0.015 14.2 0.3 16 4.3 0.0 3.2 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 CDJ82723.1 - 0.017 14.9 1.4 35 4.0 0.0 3.6 3 0 0 3 3 3 0 AAA domain Thermopsin PF05317.11 CDJ82723.1 - 0.02 14.4 0.0 45 3.4 0.0 3.1 3 0 0 3 3 3 0 Thermopsin CitT PF12431.8 CDJ82723.1 - 0.023 15.1 1.1 57 4.2 0.0 4.3 4 0 0 4 4 4 0 Transcriptional regulator DUF3967 PF13152.6 CDJ82723.1 - 0.027 14.2 6.6 8 6.3 0.0 3.9 4 0 0 4 4 3 0 Protein of unknown function (DUF3967) AAA_29 PF13555.6 CDJ82723.1 - 0.03 14.1 1.4 47 3.8 0.0 3.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain Mt_ATP-synt_B PF05405.14 CDJ82723.1 - 0.043 13.4 1.5 12 5.5 0.1 3.0 3 0 0 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Hydin_ADK PF17213.3 CDJ82723.1 - 0.073 13.3 0.0 61 3.8 0.0 3.4 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain DUF2075 PF09848.9 CDJ82723.1 - 0.1 11.8 2.9 37 3.4 0.1 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) TetR_C_3 PF08362.11 CDJ82723.1 - 0.13 12.2 0.1 24 4.8 0.0 3.1 3 0 0 3 3 3 0 YcdC-like protein, C-terminal region Helicase_C PF00271.31 CDJ82723.1 - 0.13 12.6 0.1 38 4.7 0.0 3.2 3 0 0 3 3 3 0 Helicase conserved C-terminal domain ACT_7 PF13840.6 CDJ82723.1 - 0.13 12.1 0.2 87 3.0 0.0 3.3 3 0 0 3 3 3 0 ACT domain LCIB_C_CA PF18599.1 CDJ82723.1 - 0.36 10.1 1.5 20 4.4 0.0 2.8 3 0 0 3 3 3 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases ORF45 PF17620.2 CDJ82723.1 - 0.41 10.7 3.5 2.2 8.4 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function ATP_bind_1 PF03029.17 CDJ82723.1 - 0.45 10.3 9.6 14 5.3 0.3 3.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA PF00004.29 CDJ82723.1 - 1 9.8 15.0 11 6.5 1.4 4.8 3 3 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PIN_12 PF16289.5 CDJ82723.1 - 2.5 8.6 7.9 1.1 9.7 0.4 3.0 3 0 0 3 3 3 0 PIN domain SapB_2 PF03489.17 CDJ82723.1 - 4.4 7.5 6.8 1.2e+02 2.9 0.1 4.1 4 0 0 4 4 3 0 Saposin-like type B, region 2 PMSR PF01625.21 CDJ82723.1 - 6.1 7.0 8.6 48 4.1 0.4 3.1 3 0 0 3 3 3 0 Peptide methionine sulfoxide reductase zf-C2H2 PF00096.26 CDJ82724.1 - 1.3e-13 50.6 90.9 0.0028 18.0 5.6 10.1 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ82724.1 - 3.3e-08 33.6 59.7 3.2e-06 27.3 3.9 9.8 10 1 1 11 11 11 4 Zinc-finger double domain zf-H2C2_5 PF13909.6 CDJ82724.1 - 0.0023 17.7 4.7 0.0023 17.7 4.7 8.2 9 0 0 9 9 9 4 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 CDJ82724.1 - 0.0093 16.7 74.7 0.2 12.6 2.5 9.8 9 0 0 9 9 9 5 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CDJ82724.1 - 0.053 13.8 54.6 0.94 9.8 0.5 7.1 4 3 3 7 7 7 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 CDJ82724.1 - 0.072 12.7 0.2 0.072 12.7 0.2 6.2 6 1 1 7 7 7 0 Zinc-fingers and homeoboxes C2H2 finger domain Actin_micro PF17003.5 CDJ82724.1 - 0.24 10.5 21.2 0.26 10.4 0.1 3.9 4 0 0 4 4 4 0 Putative actin-like family LMF1 PF06762.14 CDJ82725.1 - 3.4e-43 148.4 11.1 5e-43 147.8 11.1 1.2 1 0 0 1 1 1 1 Lipase maturation factor LMF1 PF06762.14 CDJ82726.1 - 6.3e-12 45.3 5.1 6.8e-12 45.2 5.1 1.0 1 0 0 1 1 1 1 Lipase maturation factor PAP2 PF01569.21 CDJ82726.1 - 0.32 10.7 4.7 0.13 12.1 1.0 1.9 2 0 0 2 2 2 0 PAP2 superfamily 2TM PF13239.6 CDJ82726.1 - 0.83 10.0 9.3 0.044 14.1 2.7 1.9 1 1 1 2 2 2 0 2TM domain Peptidase_M13_N PF05649.13 CDJ82727.1 - 7e-83 279.4 0.1 1.4e-82 278.5 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.21 CDJ82727.1 - 1.1e-67 227.6 0.4 1.6e-67 227.1 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M13 Cortexin PF11057.8 CDJ82727.1 - 0.18 11.7 2.1 0.39 10.6 2.1 1.5 1 0 0 1 1 1 0 Cortexin of kidney Rhodanese PF00581.20 CDJ82729.1 - 4.6e-12 46.4 0.0 1.5e-11 44.7 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain DUF1856 PF08983.10 CDJ82729.1 - 1.1 9.6 5.5 8.6 6.7 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1856) Pox_A51 PF04948.13 CDJ82730.1 - 0.16 10.8 0.1 0.19 10.5 0.1 1.1 1 0 0 1 1 1 0 Poxvirus A51 protein Hydrolase_4 PF12146.8 CDJ82731.1 - 2.6e-12 46.5 0.0 7.4e-12 45.0 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ82731.1 - 3.9e-12 46.4 0.0 2.6e-11 43.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ82731.1 - 9.9e-09 36.1 0.0 1.7e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 CDJ82731.1 - 0.00012 21.5 0.0 0.00022 20.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Cutinase PF01083.22 CDJ82731.1 - 0.003 17.5 0.0 0.0075 16.2 0.0 1.6 1 0 0 1 1 1 1 Cutinase PGAP1 PF07819.13 CDJ82731.1 - 0.015 15.0 0.0 0.59 9.8 0.0 2.2 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.16 CDJ82731.1 - 0.027 14.3 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase FIST PF08495.10 CDJ82731.1 - 0.038 14.0 0.0 0.093 12.7 0.0 1.5 1 1 0 1 1 1 0 FIST N domain Lipase_3 PF01764.25 CDJ82731.1 - 0.076 12.9 0.0 0.15 12.0 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 3) Globin PF00042.22 CDJ82732.1 - 2.5e-08 34.4 0.0 4.9e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Globin PRC2_HTH_1 PF18118.1 CDJ82732.1 - 0.18 12.6 1.0 0.43 11.4 1.0 1.6 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain Ank_5 PF13857.6 CDJ82733.1 - 1.1e-14 54.2 1.0 3.3e-07 30.5 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ82733.1 - 4.2e-14 52.9 2.2 8.3e-08 32.7 1.4 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ82733.1 - 6.7e-14 52.1 0.6 3e-06 27.7 0.1 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ82733.1 - 1.2e-13 49.8 1.7 0.0006 20.1 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 CDJ82733.1 - 1.4e-13 50.6 0.3 0.00014 22.1 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ion_trans PF00520.31 CDJ82733.1 - 4.2e-11 42.6 14.0 4.2e-11 42.6 14.0 1.5 2 0 0 2 2 2 1 Ion transport protein Gln-synt_C PF00120.24 CDJ82734.1 - 8.9e-44 149.9 0.0 2.7e-20 72.6 0.0 4.0 3 1 0 3 3 3 3 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 CDJ82734.1 - 2.2e-24 85.0 0.0 4.7e-12 45.5 0.0 2.4 2 0 0 2 2 2 2 Glutamine synthetase, beta-Grasp domain Methyltranf_PUA PF13636.6 CDJ82734.1 - 0.026 14.5 0.0 5.3 7.1 0.0 2.5 2 0 0 2 2 2 0 RNA-binding PUA-like domain of methyltransferase RsmF DHHC PF01529.20 CDJ82734.1 - 1.3 9.1 4.6 0.37 10.9 0.3 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase Forkhead PF00250.18 CDJ82736.1 - 1.1e-09 38.3 0.0 2.2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain BRD4_CDT PF17105.5 CDJ82736.1 - 0.23 11.1 0.5 0.45 10.1 0.5 1.4 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 DUF2207 PF09972.9 CDJ82737.1 - 0.011 14.5 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4661 PF15576.6 CDJ82737.1 - 0.11 12.4 1.0 0.14 12.0 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) DUF4689 PF15755.5 CDJ82737.1 - 0.17 11.4 0.5 0.31 10.6 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4689) Metallophos PF00149.28 CDJ82738.1 - 5.6e-28 98.8 0.0 1e-27 98.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDJ82738.1 - 0.16 12.5 0.1 0.33 11.4 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Activin_recp PF01064.23 CDJ82738.1 - 0.92 10.6 10.1 2.4 9.3 10.1 1.7 1 0 0 1 1 1 0 Activin types I and II receptor domain Pkinase_Tyr PF07714.17 CDJ82739.1 - 5.3e-78 261.9 0.0 7.2e-78 261.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ82739.1 - 2.1e-43 148.6 0.0 3.2e-43 148.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Sulfotransfer_2 PF03567.14 CDJ82739.1 - 4.2e-28 98.9 3.8 6.2e-28 98.4 3.8 1.3 1 0 0 1 1 1 1 Sulfotransferase family SH2 PF00017.24 CDJ82739.1 - 1.4e-11 44.3 0.1 5.8e-11 42.3 0.0 2.1 2 0 0 2 2 2 1 SH2 domain Kdo PF06293.14 CDJ82739.1 - 0.00032 20.1 0.3 0.00057 19.3 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AsnC_trans_reg PF01037.21 CDJ82739.1 - 0.037 14.0 0.1 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 Lrp/AsnC ligand binding domain DIM PF08194.12 CDJ82740.1 - 1.1 9.5 2.1 1.7 8.9 2.1 1.2 1 0 0 1 1 1 0 DIM protein Pkinase_Tyr PF07714.17 CDJ82741.1 - 2.6e-76 256.4 0.0 2.9e-76 256.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ82741.1 - 2.1e-41 142.0 0.0 2.7e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CDJ82741.1 - 0.00013 21.4 0.1 0.0002 20.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDJ82741.1 - 0.073 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 CDJ82741.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Astacin PF01400.24 CDJ82742.1 - 4.1e-64 215.7 0.0 1e-63 214.4 0.0 1.7 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) AMMECR1 PF01871.17 CDJ82742.1 - 2.4e-45 154.2 0.0 4.9e-45 153.1 0.0 1.5 1 0 0 1 1 1 1 AMMECR1 CUB PF00431.20 CDJ82742.1 - 1.7e-05 25.1 0.4 5.6e-05 23.5 0.3 1.8 2 0 0 2 2 2 1 CUB domain Reprolysin_4 PF13583.6 CDJ82742.1 - 0.0033 17.1 0.0 0.0057 16.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 CDJ82742.1 - 0.016 15.7 0.3 0.034 14.7 0.3 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CDJ82742.1 - 0.046 13.6 0.5 0.32 10.8 0.5 2.1 1 1 0 1 1 1 0 Matrixin Metallopep PF12044.8 CDJ82742.1 - 0.16 10.5 0.0 0.26 9.8 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family SPT2 PF08243.11 CDJ82743.1 - 4.3e-09 36.9 17.0 4.3e-09 36.9 17.0 5.5 3 2 2 5 5 5 1 SPT2 chromatin protein WSK PF03832.13 CDJ82743.1 - 0.0025 17.4 1.3 0.013 15.2 1.3 2.3 1 0 0 1 1 1 1 WSK motif Trehalase PF01204.18 CDJ82744.1 - 1.1e-42 146.5 0.0 1.3e-42 146.3 0.0 1.0 1 0 0 1 1 1 1 Trehalase Myosin_head PF00063.21 CDJ82745.1 - 6.7e-27 94.0 0.0 6.7e-27 94.0 0.0 2.4 2 1 1 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CDJ82745.1 - 2.8e-15 55.3 83.0 4e-15 54.8 83.0 1.1 1 0 0 1 1 1 1 Myosin tail IQ PF00612.27 CDJ82745.1 - 0.022 14.5 0.9 0.022 14.5 0.9 2.4 2 0 0 2 2 2 0 IQ calmodulin-binding motif TraF_2 PF13729.6 CDJ82745.1 - 0.85 8.9 6.5 2.5 7.4 0.4 2.6 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein HLH PF00010.26 CDJ82747.1 - 2.1e-16 59.6 2.3 3.4e-16 58.9 2.3 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Neuro_bHLH PF12533.8 CDJ82747.1 - 1.5e-11 45.6 0.2 2.5e-11 44.9 0.2 1.4 1 0 0 1 1 1 1 Neuronal helix-loop-helix transcription factor UQ_con PF00179.26 CDJ82750.1 - 6.6e-54 181.4 0.1 7.7e-54 181.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ82750.1 - 0.0031 17.2 0.0 0.0041 16.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CDJ82750.1 - 0.0066 16.7 0.1 0.011 16.0 0.1 1.4 1 1 0 1 1 1 1 RWD domain UFC1 PF08694.11 CDJ82750.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Cnd1 PF12717.7 CDJ82751.1 - 1.3e-13 51.3 6.1 6.9e-09 35.9 0.2 4.7 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 CDJ82751.1 - 0.0025 17.0 0.0 0.017 14.3 0.0 2.4 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 CDJ82751.1 - 0.0069 16.6 1.2 5.6 7.5 0.2 4.7 4 0 0 4 4 4 1 HEAT repeat DUF4042 PF13251.6 CDJ82751.1 - 0.053 13.2 0.3 0.35 10.6 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) DUF229 PF02995.17 CDJ82752.1 - 2.1e-127 425.8 2.2 2.9e-127 425.3 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 CDJ82752.1 - 0.0034 16.8 0.0 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 Sulfatase DUF2977 PF11192.8 CDJ82752.1 - 0.087 13.0 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2977) GalKase_gal_bdg PF10509.9 CDJ82753.1 - 7.1e-19 67.1 0.0 1.2e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 CDJ82753.1 - 3.5e-14 52.9 0.3 1.1e-13 51.3 0.1 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 CDJ82753.1 - 7.3e-10 38.9 0.6 1.5e-09 37.9 0.6 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain SCAMP PF04144.13 CDJ82754.1 - 5.2e-58 196.2 19.1 7.2e-58 195.7 19.1 1.2 1 0 0 1 1 1 1 SCAMP family DUF3552 PF12072.8 CDJ82754.1 - 0.17 11.2 5.8 0.43 10.0 4.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF5337 PF17272.2 CDJ82754.1 - 0.19 11.6 2.7 0.32 10.9 0.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5337) DUF3464 PF11947.8 CDJ82754.1 - 1.6 8.4 4.6 0.28 10.9 0.2 1.9 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Tub PF01167.18 CDJ82755.1 - 2e-29 103.0 0.0 3.5e-25 89.2 0.0 2.9 2 1 0 2 2 2 2 Tub family Cytochrom_B562 PF07361.11 CDJ82755.1 - 0.0018 18.9 0.5 0.0048 17.5 0.3 1.8 2 0 0 2 2 2 1 Cytochrome b562 DUF3527 PF12043.8 CDJ82755.1 - 0.01 15.5 1.1 0.012 15.2 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3527) AIG1 PF04548.16 CDJ82755.1 - 0.12 11.7 0.2 0.21 10.9 0.2 1.4 1 0 0 1 1 1 0 AIG1 family UQ_con PF00179.26 CDJ82756.1 - 4.9e-43 146.1 0.1 6.4e-43 145.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ82756.1 - 0.046 13.4 0.1 0.22 11.2 0.1 1.9 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 CDJ82756.1 - 0.05 13.9 0.1 0.085 13.2 0.1 1.6 1 0 0 1 1 1 0 RWD domain SGT1 PF07093.11 CDJ82756.1 - 0.13 10.7 2.0 0.15 10.5 2.0 1.1 1 0 0 1 1 1 0 SGT1 protein APG5 PF04106.12 CDJ82757.1 - 2.8e-43 148.2 0.0 4.9e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Apg5 DUF3158 PF11358.8 CDJ82757.1 - 0.023 14.5 0.0 0.052 13.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3158) dCMP_cyt_deam_1 PF00383.23 CDJ82758.1 - 8.3e-29 99.4 0.1 1.1e-28 99.0 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CDJ82758.1 - 1.1e-15 57.5 0.1 1.5e-15 57.2 0.1 1.2 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 CDJ82758.1 - 0.012 15.7 0.1 0.022 14.9 0.1 1.5 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC_N PF08210.11 CDJ82758.1 - 0.013 15.4 0.9 0.025 14.5 0.9 1.4 1 1 0 1 1 1 0 APOBEC-like N-terminal domain APOBEC4_like PF18774.1 CDJ82758.1 - 0.079 12.9 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase APOBEC4 PF18775.1 CDJ82758.1 - 0.09 12.9 0.3 0.19 11.9 0.3 1.5 1 0 0 1 1 1 0 APOBEC4 APOBEC3 PF18771.1 CDJ82758.1 - 0.12 12.5 0.2 0.2 11.8 0.2 1.3 1 0 0 1 1 1 0 APOBEC3 RhoGAP PF00620.27 CDJ82759.1 - 2e-40 138.1 0.0 3.2e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain SH3_9 PF14604.6 CDJ82759.1 - 1.4e-11 44.1 0.0 2.8e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDJ82759.1 - 4.1e-08 32.7 0.0 8.7e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 CDJ82759.1 - 1.1e-06 29.0 0.0 3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 PH domain SH3_2 PF07653.17 CDJ82759.1 - 1.4e-06 27.8 0.0 3.1e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain CNOT1_HEAT PF16418.5 CDJ82759.1 - 0.14 12.2 0.0 0.48 10.5 0.0 1.8 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat PBP PF01161.20 CDJ82760.1 - 0.0055 17.0 0.0 0.094 13.0 0.0 2.3 2 0 0 2 2 2 1 Phosphatidylethanolamine-binding protein Ly-6_related PF06579.12 CDJ82762.1 - 0.53 10.5 7.4 1.1 9.5 1.8 2.2 1 1 1 2 2 2 0 Caenorhabditis elegans ly-6-related protein RVT_1 PF00078.27 CDJ82763.1 - 7.1e-08 32.2 0.1 1.1e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Innexin PF00876.18 CDJ82764.1 - 2.3e-14 53.5 0.1 3.2e-14 53.0 0.1 1.1 1 0 0 1 1 1 1 Innexin Catalase-rel PF06628.12 CDJ82764.1 - 0.048 13.9 0.1 0.086 13.1 0.1 1.3 1 0 0 1 1 1 0 Catalase-related immune-responsive RVT_1 PF00078.27 CDJ82765.1 - 6.4e-20 71.6 0.0 7.6e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Innexin PF00876.18 CDJ82766.1 - 3.6e-28 98.9 0.5 3.9e-28 98.8 0.5 1.0 1 0 0 1 1 1 1 Innexin EGL-1 PF11430.8 CDJ82770.1 - 0.062 13.2 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Programmed cell death activator EGL-1 PH_9 PF15410.6 CDJ82771.1 - 0.0095 16.3 0.0 0.022 15.1 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Dicty_REP PF05086.12 CDJ82771.1 - 0.4 8.6 5.6 0.64 7.9 5.6 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CENP-Q PF13094.6 CDJ82771.1 - 0.85 9.8 9.9 0.025 14.8 2.6 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3439 PF11921.8 CDJ82771.1 - 2.7 8.0 12.4 0.18 11.8 6.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) MADF_DNA_bdg PF10545.9 CDJ82772.1 - 2.3e-18 66.3 0.9 5.1e-18 65.2 0.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 CDJ82772.1 - 7.3e-05 23.1 1.2 0.00039 20.7 0.5 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 CDJ82772.1 - 0.0002 21.4 0.5 0.0031 17.6 0.1 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF148 PF02520.17 CDJ82773.1 - 1.5e-15 57.3 0.0 1.9e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 ApoLp-III PF07464.11 CDJ82773.1 - 0.014 15.5 0.2 0.28 11.3 0.1 1.9 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Nucleo_P87 PF07267.11 CDJ82773.1 - 0.041 12.7 0.1 0.044 12.6 0.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 EarP PF10093.9 CDJ82773.1 - 0.084 11.9 0.4 0.13 11.4 0.4 1.3 1 0 0 1 1 1 0 Elongation-Factor P (EF-P) rhamnosyltransferase EarP INCENP_ARK-bind PF03941.15 CDJ82773.1 - 0.23 11.5 0.9 74 3.4 0.0 3.7 4 0 0 4 4 4 0 Inner centromere protein, ARK binding region NNMT_PNMT_TEMT PF01234.17 CDJ82774.1 - 2.6e-37 128.4 0.0 2.9e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_23 PF13489.6 CDJ82774.1 - 0.086 12.7 0.0 0.095 12.5 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain UPF0146 PF03686.13 CDJ82774.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Exog_C PF18026.1 CDJ82775.1 - 0.066 13.3 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Endo/exonuclease (EXOG) C-terminal domain KxDL PF10241.9 CDJ82776.1 - 0.016 15.4 2.7 0.049 13.9 2.7 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein Macoilin PF09726.9 CDJ82777.1 - 9.7 4.6 19.4 16 3.9 19.4 1.3 1 1 0 1 1 1 0 Macoilin family Zona_pellucida PF00100.23 CDJ82778.1 - 1.5e-17 64.3 4.6 1.8e-17 64.0 4.6 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain UMPH-1 PF05822.12 CDJ82780.1 - 1.6e-79 266.9 0.0 2e-79 266.6 0.0 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 CDJ82780.1 - 0.00011 22.6 0.0 0.00019 21.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ank_4 PF13637.6 CDJ82782.1 - 2.2e-20 72.7 3.0 3.2e-10 40.3 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ82782.1 - 7.6e-19 68.1 0.0 1.7e-18 67.0 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ82782.1 - 3.9e-17 62.1 0.3 1e-05 25.7 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CDJ82782.1 - 4.6e-16 58.5 0.6 9.3e-07 29.0 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 CDJ82782.1 - 2e-13 49.2 0.2 0.00043 20.5 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat DUF423 PF04241.15 CDJ82783.1 - 1.3e-21 76.6 0.0 2.1e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF423) GTP_EFTU PF00009.27 CDJ82784.1 - 5.8e-56 189.1 0.0 8.5e-56 188.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CDJ82784.1 - 6.6e-41 139.1 0.0 1.5e-40 138.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CDJ82784.1 - 5e-15 55.6 1.7 1e-14 54.6 0.3 2.3 2 1 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDJ82784.1 - 9.1e-05 22.5 0.1 0.0023 18.0 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 CDJ82784.1 - 0.0058 16.5 1.4 0.0094 15.8 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 NIF3 PF01784.18 CDJ82784.1 - 0.013 15.1 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) Semialdhyde_dhC PF02774.18 CDJ82784.1 - 0.018 15.1 0.1 0.078 13.0 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain Dynamin_N PF00350.23 CDJ82784.1 - 0.092 12.8 0.0 17 5.4 0.1 2.6 3 0 0 3 3 3 0 Dynamin family zf-C4 PF00105.18 CDJ82785.1 - 5.5e-32 110.0 14.0 1.1e-31 109.1 14.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ82785.1 - 7.1e-15 55.1 0.4 1.3e-14 54.3 0.4 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-RRPl_C4 PF17026.5 CDJ82785.1 - 0.63 10.2 9.3 0.2 11.8 6.3 1.7 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type MIR PF02815.19 CDJ82786.1 - 4.4e-14 52.8 0.2 1.1e-12 48.3 0.3 2.2 1 1 1 2 2 2 2 MIR domain Ins145_P3_rec PF08709.11 CDJ82786.1 - 0.0062 15.7 0.0 0.01 15.0 0.0 1.5 2 0 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RicinB_lectin_2 PF14200.6 CDJ82786.1 - 0.034 14.9 0.8 1.3 9.8 0.1 2.2 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like JAB PF01398.21 CDJ82787.1 - 2.2e-14 53.4 0.0 3.9e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Cob_adeno_trans PF01923.18 CDJ82787.1 - 0.059 13.5 0.2 0.14 12.3 0.1 1.6 2 0 0 2 2 2 0 Cobalamin adenosyltransferase His_Phos_1 PF00300.22 CDJ82788.1 - 2.6e-22 79.5 0.0 4.1e-22 78.8 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Cir_N PF10197.9 CDJ82789.1 - 2.1e-07 31.0 3.8 2.1e-07 31.0 3.8 4.6 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Rap_GAP PF02145.15 CDJ82790.1 - 6.2e-31 107.4 0.0 1.4e-30 106.2 0.0 1.7 1 0 0 1 1 1 1 Rap/ran-GAP SDA1 PF05285.12 CDJ82790.1 - 0.056 12.9 0.8 0.092 12.2 0.8 1.2 1 0 0 1 1 1 0 SDA1 WD40 PF00400.32 CDJ82791.1 - 1.6e-20 73.0 9.3 0.032 15.1 0.0 8.2 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ82791.1 - 1.1e-13 51.3 0.0 0.018 15.3 0.0 5.5 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDJ82791.1 - 0.00017 20.4 0.5 0.54 8.8 0.0 2.9 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CDJ82791.1 - 0.00026 19.8 0.0 2.3 6.8 0.0 4.0 2 1 1 4 4 4 1 Nup133 N terminal like Cytochrom_D1 PF02239.16 CDJ82791.1 - 0.00034 19.3 0.2 0.0051 15.4 0.0 2.6 3 0 0 3 3 3 1 Cytochrome D1 heme domain eIF2A PF08662.11 CDJ82791.1 - 0.0022 17.9 0.1 1.5 8.7 0.0 2.6 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Hira PF07569.11 CDJ82791.1 - 0.006 16.3 0.0 1.2 8.8 0.0 2.7 1 1 1 2 2 2 2 TUP1-like enhancer of split PQQ_2 PF13360.6 CDJ82791.1 - 0.025 14.2 0.2 0.22 11.1 0.0 2.4 3 1 0 3 3 3 0 PQQ-like domain HPS3_N PF14761.6 CDJ82791.1 - 0.046 13.3 0.0 4.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 WD40_like PF17005.5 CDJ82791.1 - 0.16 11.3 0.0 5.4 6.2 0.0 2.7 2 1 1 3 3 3 0 WD40-like domain PQQ PF01011.21 CDJ82791.1 - 0.3 11.1 1.5 3.5 7.7 0.2 2.9 3 0 0 3 3 2 0 PQQ enzyme repeat Pkinase PF00069.25 CDJ82792.1 - 3.1e-62 210.3 0.0 3.1e-62 210.3 0.0 2.8 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ82792.1 - 2.9e-33 115.2 0.0 7.7e-33 113.9 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ82792.1 - 9.7e-09 34.9 4.1 1.7e-08 34.1 0.0 2.9 3 0 0 3 3 3 1 Kinase-like C1_1 PF00130.22 CDJ82792.1 - 8.1e-06 25.6 0.7 1.7e-05 24.6 0.7 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 CDJ82792.1 - 0.028 14.7 2.9 0.056 13.8 2.9 1.5 1 0 0 1 1 1 0 C1 domain HTH_27 PF13463.6 CDJ82792.1 - 0.038 14.5 1.3 16 6.1 0.0 4.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain OrfB_Zn_ribbon PF07282.11 CDJ82792.1 - 0.067 13.1 0.5 0.2 11.6 0.5 1.8 1 0 0 1 1 1 0 Putative transposase DNA-binding domain APH PF01636.23 CDJ82792.1 - 0.088 12.7 10.8 0.17 11.7 0.1 4.1 3 2 1 4 4 4 0 Phosphotransferase enzyme family C2 PF00168.30 CDJ82793.1 - 1e-46 157.5 0.0 5.2e-23 81.3 0.0 2.5 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.16 CDJ82793.1 - 3.3e-35 120.9 7.0 5.8e-35 120.1 7.0 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger zf-piccolo PF05715.13 CDJ82793.1 - 0.0089 16.2 5.7 0.019 15.1 5.7 1.6 1 0 0 1 1 1 1 Piccolo Zn-finger PI3K_C2 PF00792.24 CDJ82793.1 - 0.081 12.8 0.0 0.64 9.9 0.0 2.2 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 FYVE PF01363.21 CDJ82793.1 - 5 7.3 6.9 11 6.2 6.9 1.5 1 0 0 1 1 1 0 FYVE zinc finger NMT PF01233.19 CDJ82794.1 - 1.4e-73 246.0 0.0 2.2e-73 245.4 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 CDJ82794.1 - 1.1e-63 214.5 0.1 1.7e-63 213.9 0.1 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.7 CDJ82794.1 - 0.0015 18.6 0.0 0.0056 16.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDJ82794.1 - 0.0034 17.6 0.0 0.0086 16.3 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF561 PF04481.12 CDJ82794.1 - 0.13 11.4 0.0 0.3 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF561) Rep_fac-A_C PF08646.10 CDJ82795.1 - 3.7e-11 43.0 0.0 5.1e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.25 CDJ82795.1 - 0.013 15.5 0.0 2.1 8.4 0.0 3.2 3 0 0 3 3 3 0 OB-fold nucleic acid binding domain RMI1_C PF16099.5 CDJ82795.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold Mustang PF15682.5 CDJ82796.1 - 0.065 13.3 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 Musculoskeletal, temporally activated-embryonic nuclear protein 1 TetR_C_24 PF17932.1 CDJ82796.1 - 0.077 13.3 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain ATP_bind_1 PF03029.17 CDJ82797.1 - 5.7e-76 255.5 0.0 7.1e-76 255.2 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 CDJ82797.1 - 1.6e-05 25.0 0.0 0.00021 21.4 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 CDJ82797.1 - 0.011 16.2 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 CDJ82797.1 - 0.013 16.0 0.1 0.039 14.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 CDJ82797.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_17 PF13207.6 CDJ82797.1 - 0.02 15.3 0.0 0.055 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CDJ82797.1 - 0.021 15.1 0.0 0.05 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CDJ82797.1 - 0.024 14.8 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 CDJ82797.1 - 0.03 13.9 0.0 0.28 10.7 0.0 2.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain CLP1_P PF16575.5 CDJ82797.1 - 0.046 13.5 0.0 0.84 9.4 0.0 2.1 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NACHT PF05729.12 CDJ82797.1 - 0.058 13.3 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 CDJ82797.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DNA_pol3_alpha PF07733.12 CDJ82797.1 - 0.13 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha NTPase domain AAA_30 PF13604.6 CDJ82797.1 - 0.17 11.6 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CDJ82797.1 - 0.17 12.3 0.0 0.26 11.6 0.0 1.6 1 1 1 2 2 2 0 AAA ATPase domain KTI12 PF08433.10 CDJ82797.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_29 PF13555.6 CDJ82797.1 - 0.19 11.5 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Methyltransf_10 PF05971.12 CDJ82798.1 - 1.7e-73 247.6 0.0 2.1e-73 247.3 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 CDJ82798.1 - 3.9e-06 26.5 0.0 8.5e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Ge1_WD40 PF16529.5 CDJ82798.1 - 0.0019 17.2 0.0 0.0031 16.5 0.0 1.2 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PrmA PF06325.13 CDJ82798.1 - 0.096 12.1 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Metallophos PF00149.28 CDJ82799.1 - 0.00059 20.4 0.6 0.00067 20.2 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RepA1_leader PF08048.12 CDJ82800.1 - 0.053 13.8 0.7 0.23 11.8 0.1 2.4 2 0 0 2 2 2 0 Tap RepA1 leader peptide Na_K-ATPase PF00287.18 CDJ82800.1 - 0.15 11.2 0.1 0.24 10.5 0.1 1.3 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain Collagen PF01391.18 CDJ82801.1 - 1.3e-24 85.7 91.6 6.9e-09 35.3 35.0 4.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) PDZ PF00595.24 CDJ82802.1 - 5.6e-16 58.7 0.0 6.6e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDJ82802.1 - 1.9e-08 34.0 0.0 4.1e-08 33.0 0.0 1.6 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 CDJ82802.1 - 3.8e-07 30.3 0.0 4.3e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 PDZ domain Reg_prop PF07494.11 CDJ82803.1 - 0.00085 19.3 0.3 0.011 15.8 0.0 3.0 3 0 0 3 3 3 1 Two component regulator propeller MRP-S22 PF10245.9 CDJ82803.1 - 0.088 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S22 Collagen PF01391.18 CDJ82805.1 - 1.4e-26 92.0 74.6 1.1e-09 37.9 25.1 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ82805.1 - 2.4e-12 46.7 0.0 3.5e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ82806.1 - 1.2e-24 85.9 101.0 2.9e-09 36.5 38.0 3.9 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ82806.1 - 5.1e-09 36.0 0.6 7.3e-09 35.6 0.6 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain CUB_2 PF02408.20 CDJ82807.1 - 0.04 13.7 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 CUB-like domain NuA4 PF09340.10 CDJ82808.1 - 0.0041 16.9 2.9 0.26 11.2 2.9 2.4 1 1 0 1 1 1 1 Histone acetyltransferase subunit NuA4 LBP_BPI_CETP PF01273.25 CDJ82808.1 - 0.17 11.5 0.1 0.25 10.9 0.1 1.2 1 0 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain SH3_17 PF18350.1 CDJ82809.1 - 0.024 14.5 2.5 18 5.3 0.3 4.0 4 1 1 5 5 5 0 Restriction endonuclease SH3 domain DUF948 PF06103.11 CDJ82809.1 - 3.3 8.0 10.7 9.9 6.5 0.5 3.7 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF416 PF04222.12 CDJ82809.1 - 6.8 6.1 8.5 24 4.3 0.1 4.6 1 1 4 5 5 5 0 Protein of unknown function (DUF416) Hydrolase PF00702.26 CDJ82810.1 - 9.1e-10 39.2 0.6 9.1e-10 39.2 0.6 1.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDJ82810.1 - 3.7e-05 23.6 0.1 7e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF5130 PF17174.4 CDJ82810.1 - 0.045 13.9 0.1 0.076 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5130) HAD PF12710.7 CDJ82810.1 - 0.13 12.6 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase zf-C3HC4 PF00097.25 CDJ82811.1 - 3.2e-05 23.7 26.8 0.0028 17.5 4.8 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ82811.1 - 0.0054 17.0 29.6 0.034 14.5 13.7 2.7 2 1 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ82811.1 - 0.019 14.8 28.3 0.23 11.4 5.8 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ82811.1 - 0.037 14.0 31.1 0.071 13.1 13.8 2.6 2 0 0 2 2 2 0 zinc-RING finger domain AstB PF04996.12 CDJ82811.1 - 0.067 11.8 0.0 0.13 10.9 0.0 1.5 1 1 0 1 1 1 0 Succinylarginine dihydrolase zf-RING_UBOX PF13445.6 CDJ82811.1 - 0.27 11.3 21.6 0.51 10.4 3.4 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDJ82811.1 - 3.3 7.9 24.7 0.86 9.8 3.1 3.1 2 2 1 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 CDJ82811.1 - 7.6 6.5 20.9 0.88 9.5 6.7 2.6 2 1 0 2 2 2 0 zf-RING of BARD1-type protein RVT_1 PF00078.27 CDJ82814.1 - 3.1e-14 53.0 0.0 7e-14 51.9 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDJ82814.1 - 0.031 14.5 0.3 0.067 13.5 0.3 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase DivIC PF04977.15 CDJ82814.1 - 0.074 12.8 0.1 0.35 10.7 0.0 2.0 2 0 0 2 2 2 0 Septum formation initiator RT_RNaseH_2 PF17919.1 CDJ82814.1 - 0.18 11.8 1.7 0.23 11.5 0.6 1.6 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase PhoQ_Sensor PF08918.10 CDJ82814.1 - 0.43 10.4 1.7 1.7 8.4 0.2 2.0 1 1 1 2 2 2 0 PhoQ Sensor MRP-S34 PF16053.5 CDJ82815.1 - 1.8e-37 127.8 0.0 3.1e-37 127.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 CRAL_TRIO PF00650.20 CDJ82816.1 - 1.3e-16 60.8 0.0 7.7e-16 58.2 0.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO domain DUF1409 PF07197.12 CDJ82816.1 - 0.026 14.4 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) EB PF01683.18 CDJ82817.1 - 2e-18 66.4 18.6 8.1e-10 38.8 1.3 3.1 3 0 0 3 3 3 3 EB module Dickkopf_N PF04706.12 CDJ82817.1 - 0.046 14.2 16.2 0.11 12.9 0.4 3.4 3 0 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region Spermine_synth PF01564.17 CDJ82818.1 - 0.0014 18.1 0.2 0.0028 17.1 0.1 1.5 2 0 0 2 2 2 1 Spermine/spermidine synthase domain DUF3574 PF12098.8 CDJ82818.1 - 0.12 12.2 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) Endonuclease_7 PF02945.15 CDJ82819.1 - 0.012 15.6 2.5 0.012 15.6 2.5 2.8 3 0 0 3 3 3 0 Recombination endonuclease VII zf-H2C2_2 PF13465.6 CDJ82819.1 - 0.012 16.0 22.6 0.17 12.3 0.3 6.4 6 0 0 6 6 6 0 Zinc-finger double domain DUF2752 PF10825.8 CDJ82819.1 - 0.051 13.6 1.4 0.44 10.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) DUF2063 PF09836.9 CDJ82819.1 - 0.12 12.7 0.2 7.2 6.9 0.1 2.9 3 0 0 3 3 3 0 Putative DNA-binding domain AKAP95 PF04988.12 CDJ82819.1 - 0.63 10.3 9.5 2.8 8.1 0.0 3.3 3 1 1 4 4 4 0 A-kinase anchoring protein 95 (AKAP95) HypA PF01155.19 CDJ82819.1 - 0.69 10.0 9.8 0.34 11.0 0.6 3.3 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-TRAF PF02176.18 CDJ82819.1 - 0.84 10.4 11.0 1.8 9.3 4.5 2.9 2 0 0 2 2 2 0 TRAF-type zinc finger Zn_ribbon_SprT PF17283.2 CDJ82819.1 - 4.5 7.3 7.1 1 9.3 0.2 3.1 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zf_C2H2_ZHX PF18387.1 CDJ82819.1 - 9.6 5.9 9.2 3.2 7.5 0.5 3.7 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain RVT_1 PF00078.27 CDJ82820.1 - 3.5e-41 141.1 0.0 5.9e-41 140.4 0.0 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_48 PF17906.1 CDJ82821.1 - 0.00017 21.7 0.1 0.00028 20.9 0.1 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 CDJ82821.1 - 0.037 14.6 0.0 0.049 14.3 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain E3_UFM1_ligase PF09743.9 CDJ82821.1 - 0.082 12.5 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 E3 UFM1-protein ligase 1 HTH_Tnp_Tc3_2 PF01498.18 CDJ82821.1 - 0.088 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Transposase MM_CoA_mutase PF01642.22 CDJ82822.1 - 5.3e-237 787.4 1.1 7e-237 787.0 1.1 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 CDJ82822.1 - 2e-14 53.7 0.4 4.6e-14 52.5 0.4 1.6 1 0 0 1 1 1 1 B12 binding domain Aldo_ket_red PF00248.21 CDJ82823.1 - 0.00027 20.2 0.0 0.00046 19.5 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family 7tm_1 PF00001.21 CDJ82824.1 - 5e-46 157.2 17.7 5.9e-46 156.9 17.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ82824.1 - 6e-08 32.4 15.2 1.2e-07 31.4 15.2 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF3975 PF13126.6 CDJ82824.1 - 0.08 13.4 0.1 0.37 11.2 0.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3975) MFS_1 PF07690.16 CDJ82824.1 - 0.2 10.5 14.9 1.9 7.3 8.5 2.3 1 1 0 2 2 2 0 Major Facilitator Superfamily Git3 PF11710.8 CDJ82824.1 - 0.31 10.8 10.2 2.2 8.0 10.2 2.1 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Saf_2TM PF18303.1 CDJ82824.1 - 0.71 9.5 5.2 0.22 11.1 0.1 2.5 2 1 1 3 3 3 0 SAVED-fused 2TM effector domain DUF2116 PF09889.9 CDJ82824.1 - 0.94 9.5 0.0 0.94 9.5 0.0 3.6 3 1 1 4 4 4 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Ion_trans_2 PF07885.16 CDJ82825.1 - 9e-18 64.0 1.4 9e-18 64.0 1.4 1.5 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 CDJ82825.1 - 2.3e-05 23.7 0.0 2.8e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Ion transport protein Lig_chan PF00060.26 CDJ82825.1 - 0.0012 18.7 0.0 0.0024 17.7 0.0 1.7 1 1 0 1 1 1 1 Ligand-gated ion channel ACOX PF01756.19 CDJ82826.1 - 6.9e-54 182.1 1.3 6.9e-54 182.1 1.3 1.7 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.24 CDJ82826.1 - 0.26 11.5 9.3 0.16 12.2 5.7 2.4 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain ACOX PF01756.19 CDJ82827.1 - 1.8e-53 180.8 1.7 1.8e-53 180.8 1.7 1.7 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 CDJ82827.1 - 5.5e-24 85.1 0.1 1.4e-23 83.7 0.1 1.8 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 CDJ82827.1 - 2.7e-10 40.3 0.0 5.1e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 CDJ82827.1 - 0.011 16.0 0.6 0.034 14.4 0.6 2.0 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain PIG-L PF02585.17 CDJ82827.1 - 0.13 12.9 0.1 0.35 11.5 0.1 1.8 1 0 0 1 1 1 0 GlcNAc-PI de-N-acetylase GRP PF07172.11 CDJ82828.1 - 0.00085 20.0 0.6 0.0011 19.7 0.6 1.2 1 0 0 1 1 1 1 Glycine rich protein family SCVP PF17619.2 CDJ82836.1 - 3.2e-05 24.7 0.0 6.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Secreted clade V proteins CDC73_C PF05179.14 CDJ82837.1 - 0.15 11.7 0.2 0.26 10.9 0.2 1.4 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family, C-terminal RRM_1 PF00076.22 CDJ82838.1 - 1.7e-83 274.4 8.0 8.4e-19 67.2 0.2 6.4 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ82838.1 - 2.3e-07 30.8 0.2 15 5.8 0.0 6.0 6 0 0 6 6 6 1 RNA recognition motif Limkain-b1 PF11608.8 CDJ82838.1 - 2.5e-06 27.5 0.9 0.95 9.6 0.0 5.8 5 2 0 5 5 5 2 Limkain b1 RRM_occluded PF16842.5 CDJ82838.1 - 7.3e-05 22.5 0.0 0.68 9.8 0.0 4.3 4 0 0 4 4 4 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CDJ82838.1 - 0.00031 20.7 3.1 3.1 7.9 0.0 4.8 5 0 0 5 5 5 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CDJ82838.1 - 0.0015 18.1 0.0 1.3 8.7 0.0 4.1 3 1 1 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 CDJ82838.1 - 0.014 15.2 0.0 2.7 7.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) CBF PF03914.17 CDJ82838.1 - 0.13 12.3 1.8 16 5.5 0.4 2.7 2 0 0 2 2 2 0 CBF/Mak21 family Zip PF02535.22 CDJ82838.1 - 7.3 5.7 9.2 1.7 7.8 2.4 2.7 3 0 0 3 3 3 0 ZIP Zinc transporter Lectin_C PF00059.21 CDJ82840.1 - 0.0021 18.8 0.4 0.0032 18.2 0.4 1.4 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 CDJ82841.1 - 8.2e-08 33.0 0.0 1.4e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Lectin C-type domain DUF2868 PF11067.8 CDJ82842.1 - 0.06 12.8 2.4 0.097 12.2 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) DUF760 PF05542.11 CDJ82842.1 - 0.12 12.7 1.1 1.5 9.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF760) Mito_fiss_reg PF05308.11 CDJ82842.1 - 0.85 9.7 7.6 6.4 6.8 6.4 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Glyco_transf_49 PF13896.6 CDJ82843.1 - 6.3e-54 183.5 2.9 7.5e-54 183.3 2.9 1.1 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Ribosomal_L12 PF00542.19 CDJ82844.1 - 2.3e-21 75.9 5.5 2.3e-21 75.9 5.5 2.0 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 CDJ82844.1 - 2.9e-10 39.7 6.5 2.9e-10 39.7 6.5 2.7 2 1 1 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain CSD PF00313.22 CDJ82845.1 - 4.9e-23 80.8 0.0 1e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain DUF2451 PF10474.9 CDJ82846.1 - 1.4e-81 273.7 0.1 3.5e-81 272.4 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 CDJ82846.1 - 5.5e-74 249.1 9.6 1e-73 248.2 9.6 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Dor1 PF04124.12 CDJ82846.1 - 0.0039 15.9 2.6 0.019 13.6 1.7 2.3 2 0 0 2 2 2 1 Dor1-like family MMS22L_C PF14911.6 CDJ82846.1 - 0.0064 15.6 0.4 0.012 14.8 0.4 1.4 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, C-terminal DUF2408 PF10303.9 CDJ82846.1 - 0.085 13.4 3.7 0.66 10.5 2.0 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) GMP_PDE_delta PF05351.11 CDJ82847.1 - 1e-72 243.4 2.4 1.3e-72 243.0 2.4 1.1 1 0 0 1 1 1 1 GMP-PDE, delta subunit PHD PF00628.29 CDJ82848.1 - 2e-17 62.8 22.2 7e-11 41.9 7.3 2.5 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.6 CDJ82848.1 - 8.7e-05 22.7 12.1 0.028 14.7 0.2 3.1 2 1 1 3 3 3 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CDJ82848.1 - 0.00032 20.8 6.2 0.25 11.5 0.8 2.7 2 0 0 2 2 2 2 PHD-zinc-finger like domain Zf_RING PF16744.5 CDJ82848.1 - 0.0021 18.1 2.2 0.0021 18.1 2.2 2.8 2 0 0 2 2 2 1 KIAA1045 RING finger C1_1 PF00130.22 CDJ82848.1 - 0.0026 17.6 0.8 0.0026 17.6 0.8 3.2 4 0 0 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) XRN_N PF03159.18 CDJ82848.1 - 0.039 13.4 0.0 0.9 8.9 0.0 2.2 2 0 0 2 2 2 0 XRN 5'-3' exonuclease N-terminus PHD_2 PF13831.6 CDJ82848.1 - 0.35 10.5 15.9 2.2 7.9 5.6 2.9 2 1 0 2 2 2 0 PHD-finger C1_2 PF03107.16 CDJ82848.1 - 3.1 8.2 15.6 0.68 10.3 0.9 3.7 3 0 0 3 3 3 0 C1 domain Peptidase_M8 PF01457.16 CDJ82850.1 - 1.1e-33 116.8 3.4 1.3e-33 116.5 3.4 1.0 1 0 0 1 1 1 1 Leishmanolysin FANCI_S4 PF14678.6 CDJ82851.1 - 0.17 10.9 7.0 13 4.9 7.0 2.3 1 1 0 1 1 1 0 FANCI solenoid 4 Histone PF00125.24 CDJ82852.1 - 5e-13 49.5 0.0 7.1e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CDJ82852.1 - 0.00016 21.9 0.0 0.00026 21.2 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1931 PF09123.11 CDJ82852.1 - 0.038 14.1 0.0 0.054 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) IpaB_EvcA PF03278.13 CDJ82852.1 - 0.077 12.7 0.1 0.089 12.5 0.1 1.0 1 0 0 1 1 1 0 IpaB/EvcA family THF_DHG_CYH_C PF02882.19 CDJ82854.1 - 0.029 13.7 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RVT_1 PF00078.27 CDJ82855.1 - 4.2e-08 33.0 0.0 6.9e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDJ82856.1 - 0.00088 19.1 0.1 0.0034 17.2 0.0 2.0 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ82856.1 - 0.0057 16.2 0.0 0.0095 15.5 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-SNAP50_C PF12251.8 CDJ82857.1 - 7.7e-57 192.2 0.1 8.8e-57 192.0 0.1 1.0 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Pkinase PF00069.25 CDJ82858.1 - 8.5e-17 61.4 0.1 1.4e-16 60.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ82858.1 - 8.7e-08 31.8 0.1 1.7e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ82858.1 - 0.17 10.6 0.0 0.17 10.6 0.0 3.7 2 2 1 3 3 3 0 Fungal protein kinase DUF1213 PF06740.12 CDJ82859.1 - 0.11 13.1 0.0 0.25 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1213) DUF5356 PF17309.2 CDJ82860.1 - 1.7e-37 128.5 10.8 1.7e-37 128.5 10.8 2.4 2 0 0 2 2 2 1 Family of unknown function (DUF5356) C1_1 PF00130.22 CDJ82861.1 - 0.011 15.6 3.0 0.011 15.6 3.0 3.2 3 1 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 CDJ82861.1 - 0.016 15.1 7.8 0.016 15.1 7.8 3.6 2 2 1 3 3 3 0 PHD-finger SR-25 PF10500.9 CDJ82861.1 - 0.088 12.4 9.4 0.13 11.8 9.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF913 PF06025.12 CDJ82861.1 - 0.13 11.2 1.3 0.16 10.9 1.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) zinc_ribbon_2 PF13240.6 CDJ82861.1 - 0.62 9.9 4.3 14 5.6 0.2 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Cwf_Cwc_15 PF04889.12 CDJ82861.1 - 0.79 9.4 11.0 1.1 8.9 11.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-RING_9 PF13901.6 CDJ82861.1 - 0.8 9.6 10.9 0.052 13.5 2.2 2.7 3 0 0 3 3 3 0 Putative zinc-RING and/or ribbon DUF1664 PF07889.12 CDJ82864.1 - 0.22 11.5 2.6 0.39 10.8 2.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 CDJ82864.1 - 2 7.7 8.0 3.1 7.0 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 CDJ82864.1 - 7.3 6.8 12.9 16 5.7 12.9 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Lipase_3 PF01764.25 CDJ82865.1 - 5.1e-28 97.7 0.0 7.7e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) FYVE PF01363.21 CDJ82865.1 - 0.095 12.9 7.2 0.17 12.0 7.3 1.4 1 1 0 1 1 1 0 FYVE zinc finger PSI PF01437.25 CDJ82865.1 - 5.6 7.6 9.7 21 5.7 9.7 1.9 1 1 0 1 1 1 0 Plexin repeat Sec62 PF03839.16 CDJ82866.1 - 1.4e-17 63.9 12.4 1.4e-17 63.9 12.4 1.5 2 0 0 2 2 2 1 Translocation protein Sec62 DEP PF00610.21 CDJ82866.1 - 0.00039 20.4 0.0 0.0014 18.7 0.0 1.9 1 1 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CDC27 PF09507.10 CDJ82866.1 - 0.00091 18.7 21.2 0.00099 18.6 21.2 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Presenilin PF01080.17 CDJ82866.1 - 0.01 14.7 4.3 0.011 14.5 4.3 1.1 1 0 0 1 1 1 1 Presenilin NPR3 PF03666.13 CDJ82866.1 - 0.017 13.9 8.8 0.02 13.7 8.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 CDJ82866.1 - 0.018 13.3 13.3 0.022 13.1 13.3 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM60A PF15396.6 CDJ82866.1 - 0.042 13.8 7.6 0.052 13.6 7.6 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF4484 PF14831.6 CDJ82866.1 - 0.07 13.2 6.8 0.094 12.7 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Gti1_Pac2 PF09729.9 CDJ82866.1 - 0.1 12.7 10.7 0.11 12.5 10.2 1.3 1 1 0 1 1 1 0 Gti1/Pac2 family SLC12 PF03522.15 CDJ82866.1 - 0.12 11.4 9.2 0.13 11.2 9.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RNA_pol_Rpc4 PF05132.14 CDJ82866.1 - 0.17 12.3 12.5 0.3 11.5 12.5 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2151 PF10221.9 CDJ82866.1 - 0.29 9.7 11.5 0.32 9.5 11.5 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Afi1 PF07792.12 CDJ82866.1 - 0.35 11.4 11.8 0.52 10.8 11.8 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF913 PF06025.12 CDJ82866.1 - 0.38 9.7 8.7 0.47 9.4 8.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 CDJ82866.1 - 0.38 10.5 16.8 0.49 10.2 16.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CobT PF06213.12 CDJ82866.1 - 0.44 9.9 17.3 0.61 9.4 17.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Astro_capsid_p PF12226.8 CDJ82866.1 - 0.48 9.5 8.8 0.62 9.2 8.8 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein GAGA_bind PF06217.12 CDJ82866.1 - 0.51 10.6 10.8 0.66 10.2 10.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1980 PF09323.10 CDJ82866.1 - 0.6 10.0 6.2 1.1 9.1 6.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) SAPS PF04499.15 CDJ82866.1 - 0.85 8.3 9.4 0.87 8.3 9.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.22 CDJ82866.1 - 1.1 8.4 10.8 1.5 8.0 10.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter ALMT PF11744.8 CDJ82866.1 - 1.4 7.6 10.7 1.8 7.3 10.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Ax_dynein_light PF10211.9 CDJ82866.1 - 1.8 8.5 15.4 2.6 8.0 15.4 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain Neur_chan_memb PF02932.16 CDJ82866.1 - 2.5 8.1 5.3 3 7.8 5.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF5427 PF10310.9 CDJ82866.1 - 4.8 6.0 17.2 6 5.7 17.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) VIR_N PF15912.5 CDJ82866.1 - 4.8 6.7 12.9 6.5 6.3 12.9 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal V_ATPase_I PF01496.19 CDJ82866.1 - 6.4 4.6 10.9 7.7 4.3 10.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LIM PF00412.22 CDJ82867.1 - 3.1e-31 107.4 31.3 1e-12 48.1 8.9 3.3 3 0 0 3 3 3 3 LIM domain Yippee-Mis18 PF03226.14 CDJ82867.1 - 0.65 10.2 19.3 0.084 13.1 6.4 2.7 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly CAP_N PF01213.19 CDJ82867.1 - 4.5 6.7 5.3 7 6.0 5.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CH PF00307.31 CDJ82868.1 - 1.4e-83 276.2 4.4 2.3e-19 69.6 0.2 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CDJ82868.1 - 8.2e-06 25.6 0.2 0.023 14.5 0.1 2.9 2 0 0 2 2 2 2 CAMSAP CH domain TM231 PF10149.9 CDJ82869.1 - 2.9e-47 161.5 4.5 3.3e-47 161.3 4.5 1.0 1 0 0 1 1 1 1 Transmembrane protein 231 zf-CCCH PF00642.24 CDJ82871.1 - 1.4e-09 37.6 29.0 0.00013 21.7 4.7 3.4 2 1 1 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ82871.1 - 4.9e-07 29.6 29.6 1.3e-05 25.1 6.0 4.0 3 1 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 CDJ82871.1 - 0.00012 21.7 2.9 0.00012 21.7 2.9 3.7 3 1 0 3 3 3 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 CDJ82871.1 - 0.00021 21.5 9.7 0.023 14.9 5.5 2.3 1 1 1 2 2 2 2 Zinc-finger containing family Torus PF16131.5 CDJ82871.1 - 0.0019 18.9 17.5 0.0036 18.0 1.3 3.2 1 1 2 3 3 3 2 Torus domain UQ_con PF00179.26 CDJ82872.1 - 5e-31 107.2 0.0 6e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ82872.1 - 0.033 13.9 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Mago_nashi PF02792.14 CDJ82873.1 - 7.6e-78 259.5 0.1 8.5e-78 259.3 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein Hist_deacetyl PF00850.19 CDJ82874.1 - 8.2e-84 281.7 0.0 1.1e-83 281.2 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain HLH PF00010.26 CDJ82874.1 - 5.2e-12 45.5 4.2 1.1e-11 44.5 4.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain AT_hook PF02178.19 CDJ82876.1 - 0.0061 16.3 1.2 0.019 14.8 1.2 1.9 1 0 0 1 1 1 1 AT hook motif zf-MYST PF17772.1 CDJ82876.1 - 0.087 12.5 0.2 0.18 11.4 0.2 1.5 1 0 0 1 1 1 0 MYST family zinc finger domain Pyr_redox_2 PF07992.14 CDJ82877.1 - 9.4e-67 225.3 3.5 1.2e-66 224.9 3.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CDJ82877.1 - 3.2e-41 140.0 0.3 2.2e-40 137.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CDJ82877.1 - 3.1e-19 69.3 6.9 1.3e-16 60.9 0.7 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CDJ82877.1 - 5.9e-14 52.0 0.7 1e-13 51.2 0.7 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CDJ82877.1 - 1.2e-10 41.3 7.3 4.1e-10 39.6 0.1 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CDJ82877.1 - 3.9e-10 39.4 3.7 1.2e-07 31.2 0.5 3.1 3 0 0 3 3 3 2 FAD binding domain FAD_binding_3 PF01494.19 CDJ82877.1 - 8.3e-09 35.1 4.8 0.0065 15.8 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain GIDA PF01134.22 CDJ82877.1 - 1.3e-08 34.4 1.7 4.1e-07 29.4 0.2 2.5 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 CDJ82877.1 - 8.2e-08 32.4 0.8 0.00047 20.3 0.1 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 CDJ82877.1 - 1.9e-07 30.6 5.3 0.0038 16.5 0.3 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 CDJ82877.1 - 9.6e-07 27.8 10.8 0.00045 19.1 0.9 3.5 4 0 0 4 4 4 2 HI0933-like protein K_oxygenase PF13434.6 CDJ82877.1 - 7.7e-06 25.3 1.7 0.074 12.2 0.2 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 CDJ82877.1 - 9.2e-06 25.1 1.7 4e-05 23.0 0.1 2.2 2 0 0 2 2 2 1 Thi4 family UDPG_MGDP_dh_N PF03721.14 CDJ82877.1 - 0.0046 16.5 4.9 1.3 8.6 0.7 3.1 2 1 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 CDJ82877.1 - 0.005 16.2 2.3 0.8 9.0 0.4 2.8 2 1 1 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 CDJ82877.1 - 0.019 14.9 1.1 0.36 10.7 0.3 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 CDJ82877.1 - 0.05 14.1 0.1 21 5.6 0.0 3.0 3 0 0 3 3 3 0 XdhC Rossmann domain Lycopene_cycl PF05834.12 CDJ82877.1 - 0.11 11.5 4.5 0.61 9.1 0.3 3.0 3 0 0 3 3 3 0 Lycopene cyclase protein DAO PF01266.24 CDJ82877.1 - 9.6 5.7 17.9 0.23 11.0 0.8 3.9 2 2 1 4 4 4 0 FAD dependent oxidoreductase DOMON PF03351.17 CDJ82878.1 - 1.3e-06 28.7 0.1 2.8e-06 27.5 0.1 1.6 1 1 0 1 1 1 1 DOMON domain LIM PF00412.22 CDJ82879.1 - 5.4e-10 39.3 9.0 7.9e-10 38.8 9.0 1.2 1 0 0 1 1 1 1 LIM domain zf-CXXC PF02008.20 CDJ82879.1 - 0.6 10.2 6.5 0.24 11.4 1.8 2.2 1 1 1 2 2 2 0 CXXC zinc finger domain DUF2175 PF09943.9 CDJ82879.1 - 3 8.2 7.7 4.4 7.7 4.7 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Arg_decarbox_C PF17944.1 CDJ82880.1 - 0.52 10.9 4.2 14 6.3 0.1 3.6 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension ShK PF01549.24 CDJ82881.1 - 5.1e-05 23.7 3.7 7e-05 23.3 3.7 1.2 1 0 0 1 1 1 1 ShK domain-like PTN_MK_N PF05196.13 CDJ82881.1 - 0.074 13.3 3.6 0.12 12.6 3.6 1.3 1 0 0 1 1 1 0 PTN/MK heparin-binding protein family, N-terminal domain BTB PF00651.31 CDJ82882.1 - 1.7e-08 34.7 0.0 2.8e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BAR PF03114.18 CDJ82882.1 - 0.011 15.4 0.1 0.015 14.9 0.1 1.1 1 0 0 1 1 1 0 BAR domain Tim44 PF04280.15 CDJ82883.1 - 1.1e-20 74.3 0.1 2.9e-20 72.9 0.0 1.7 2 0 0 2 2 2 1 Tim44-like domain MBA1 PF07961.11 CDJ82883.1 - 0.002 17.2 0.0 0.0034 16.5 0.0 1.4 1 0 0 1 1 1 1 MBA1-like protein DSS1_SEM1 PF05160.13 CDJ82884.1 - 1.3e-17 63.6 19.4 1.6e-17 63.3 19.4 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family MFS_1 PF07690.16 CDJ82885.1 - 3.6e-44 151.1 39.1 6.9e-44 150.2 34.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HMG_box PF00505.19 CDJ82886.1 - 0.024 15.1 0.7 0.058 13.8 0.7 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ82886.1 - 0.027 15.1 1.8 0.078 13.6 1.8 1.8 1 0 0 1 1 1 0 HMG-box domain RecQ5 PF06959.11 CDJ82887.1 - 0.039 13.9 4.3 0.044 13.8 4.3 1.0 1 0 0 1 1 1 0 RecQ helicase protein-like 5 (RecQ5) SDF PF00375.18 CDJ82889.1 - 1.2e-135 452.5 33.6 1.4e-135 452.3 33.6 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF2650 PF10853.8 CDJ82890.1 - 2.8e-13 49.3 4.8 6e-13 48.3 4.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2650) Neur_chan_LBD PF02931.23 CDJ82891.1 - 6.3e-38 130.4 0.7 1.1e-37 129.6 0.7 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ82891.1 - 3.7e-35 122.1 0.1 4.9e-35 121.7 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region FLYWCH PF04500.16 CDJ82893.1 - 9.5e-06 25.6 0.3 1.5e-05 25.0 0.3 1.3 1 0 0 1 1 1 1 FLYWCH zinc finger domain Tetraspanin PF00335.20 CDJ82894.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.7 1 1 0 1 1 1 0 Tetraspanin family Porin_3 PF01459.22 CDJ82895.1 - 3.2e-63 213.7 1.2 3.6e-63 213.6 1.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin DS PF01916.17 CDJ82895.1 - 0.026 13.8 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Deoxyhypusine synthase NFACT-R_1 PF05670.13 CDJ82896.1 - 1.4e-37 128.6 0.0 2e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 NFACT protein RNA binding domain Pinin_SDK_memA PF04696.13 CDJ82896.1 - 0.061 13.4 15.0 0.11 12.5 15.0 1.5 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region MLANA PF14991.6 CDJ82896.1 - 0.22 11.8 0.4 0.33 11.2 0.4 1.4 1 0 0 1 1 1 0 Protein melan-A DUF1943 PF09172.11 CDJ82896.1 - 0.5 9.6 1.5 0.66 9.2 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF4337 PF14235.6 CDJ82896.1 - 9.3 6.3 6.4 12 6.0 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) SPRY PF00622.28 CDJ82897.1 - 3.9e-16 59.2 0.0 6.3e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.16 CDJ82897.1 - 1.5e-09 38.0 3.0 4e-09 36.7 3.0 1.8 1 0 0 1 1 1 1 SOCS box Astro_capsid_p PF12226.8 CDJ82898.1 - 0.01 15.0 17.0 0.014 14.5 17.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF4746 PF15928.5 CDJ82898.1 - 0.32 10.4 17.5 0.39 10.1 17.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 CDJ82898.1 - 0.53 8.5 16.1 0.54 8.5 16.1 1.0 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 CDJ82898.1 - 0.98 7.9 14.5 1.5 7.3 14.5 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Presenilin PF01080.17 CDJ82898.1 - 2.2 7.0 6.9 2.3 6.9 6.9 1.1 1 0 0 1 1 1 0 Presenilin DivIC PF04977.15 CDJ82899.1 - 0.012 15.4 1.3 0.012 15.4 1.3 4.0 2 2 2 4 4 4 0 Septum formation initiator RTBV_P46 PF06216.11 CDJ82899.1 - 0.021 13.7 0.8 0.052 12.4 0.2 1.8 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein Baculo_PEP_C PF04513.12 CDJ82899.1 - 0.043 13.8 9.6 0.04 13.9 6.8 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.13 CDJ82899.1 - 0.19 12.1 8.2 0.36 11.2 0.1 3.8 3 1 0 3 3 3 0 Lipoprotein leucine-zipper Speriolin_C PF15059.6 CDJ82899.1 - 0.38 10.9 3.5 2.1 8.4 0.1 2.7 1 1 1 2 2 2 0 Speriolin C-terminus MbeD_MobD PF04899.12 CDJ82899.1 - 0.44 10.7 8.0 0.072 13.2 1.3 2.9 2 2 0 3 3 3 0 MbeD/MobD like TBD PF12845.7 CDJ82899.1 - 2.2 8.3 11.8 0.14 12.1 1.1 3.3 4 0 0 4 4 4 0 TBD domain Dzip-like_N PF13815.6 CDJ82899.1 - 3.9 7.5 14.5 0.16 12.0 4.2 2.7 1 1 1 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF3138 PF11336.8 CDJ82899.1 - 4.5 5.8 8.8 1.5 7.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF3107 PF11305.8 CDJ82899.1 - 7.7 6.8 6.5 4.2 7.7 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3107) DUF5320 PF17253.2 CDJ82899.1 - 9.8 7.3 9.4 7.5 7.7 0.9 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5320) TIP49 PF06068.13 CDJ82900.1 - 8.9e-144 479.0 0.1 1.1e-143 478.7 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CDJ82900.1 - 6e-17 61.5 0.5 1.6e-16 60.2 0.3 1.9 2 0 0 2 2 1 1 TIP49 AAA-lid domain AAA PF00004.29 CDJ82900.1 - 1.4e-10 41.7 2.0 1e-06 29.2 0.1 3.2 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ82900.1 - 1.6e-07 31.8 0.2 2e-06 28.3 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDJ82900.1 - 1.5e-06 28.5 0.0 0.013 15.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 CDJ82900.1 - 3.6e-06 26.8 0.1 0.0014 18.4 0.1 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CDJ82900.1 - 0.0002 21.4 0.3 0.021 14.8 0.0 3.2 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 CDJ82900.1 - 0.00023 20.5 0.1 0.0034 16.7 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 CDJ82900.1 - 0.00024 20.8 0.9 0.0087 15.8 0.2 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 CDJ82900.1 - 0.0021 18.1 0.0 0.18 11.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CDJ82900.1 - 0.003 17.5 0.1 0.01 15.8 0.0 1.9 2 0 0 2 2 2 1 NACHT domain DnaB_C PF03796.15 CDJ82900.1 - 0.0062 15.9 0.1 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_7 PF12775.7 CDJ82900.1 - 0.0066 16.0 0.1 0.049 13.1 0.1 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_19 PF13245.6 CDJ82900.1 - 0.013 15.8 0.2 0.061 13.7 0.2 2.1 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CDJ82900.1 - 0.018 14.5 1.6 0.16 11.3 0.5 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ResIII PF04851.15 CDJ82900.1 - 0.018 15.0 0.1 1.9 8.5 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 CDJ82900.1 - 0.027 15.0 0.0 0.05 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CDJ82900.1 - 0.037 14.0 0.9 0.067 13.2 0.1 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE KorB PF08535.10 CDJ82900.1 - 0.08 13.0 0.0 0.41 10.7 0.0 2.2 2 0 0 2 2 2 0 KorB domain AAA_25 PF13481.6 CDJ82900.1 - 0.081 12.5 0.0 0.48 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CDJ82900.1 - 0.094 13.1 0.0 0.42 11.0 0.0 2.1 2 0 0 2 2 2 0 RNA helicase ADH_zinc_N PF00107.26 CDJ82901.1 - 2.4e-18 66.4 0.0 3.7e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDJ82901.1 - 5.2e-09 35.9 0.0 9.5e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CDJ82901.1 - 3.4e-06 28.2 0.0 6.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CoA_binding_2 PF13380.6 CDJ82901.1 - 0.00077 19.9 0.0 0.15 12.6 0.0 2.5 1 1 0 1 1 1 1 CoA binding domain HTH_23 PF13384.6 CDJ82901.1 - 0.15 11.9 0.0 0.52 10.2 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain ADH_zinc_N PF00107.26 CDJ82902.1 - 7.1e-16 58.4 0.0 1.2e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDJ82902.1 - 4.1e-09 36.3 0.1 8.6e-09 35.3 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CDJ82902.1 - 3.6e-05 24.8 0.0 6.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CoA_binding_2 PF13380.6 CDJ82902.1 - 0.004 17.6 0.0 0.26 11.8 0.0 2.5 1 1 0 1 1 1 1 CoA binding domain PALP PF00291.25 CDJ82902.1 - 0.006 16.0 0.0 0.0088 15.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HisG_C PF08029.11 CDJ82902.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 HisG, C-terminal domain RRM_1 PF00076.22 CDJ82903.1 - 1.3e-15 56.9 0.0 8.9e-08 31.8 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 CDJ82903.1 - 0.046 13.7 19.2 0.065 13.2 19.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L7Ae PF01248.26 CDJ82904.1 - 1.7e-28 98.2 0.2 2e-28 97.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CDJ82904.1 - 9.8e-05 22.5 0.3 0.00012 22.2 0.3 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 CDJ82904.1 - 0.00042 20.2 0.0 0.00056 19.7 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain YadA_stalk PF05662.14 CDJ82904.1 - 0.059 13.7 0.3 8.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin FlaC_arch PF05377.11 CDJ82904.1 - 0.068 13.6 0.3 0.16 12.4 0.3 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Tetraspanin PF00335.20 CDJ82905.1 - 8.2e-45 153.3 6.4 9.3e-45 153.1 6.4 1.0 1 0 0 1 1 1 1 Tetraspanin family Collagen PF01391.18 CDJ82906.1 - 2.3e-24 84.9 112.4 1.1e-09 37.9 35.0 4.1 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ82906.1 - 6.6e-05 22.9 0.0 9.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain 7tm_1 PF00001.21 CDJ82907.1 - 3.1e-27 95.6 25.0 3.1e-27 95.6 25.0 1.7 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Pkinase PF00069.25 CDJ82908.1 - 3.2e-19 69.3 0.0 4.2e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ82908.1 - 4e-11 42.7 0.0 5.6e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ82908.1 - 1.1e-05 24.4 0.0 1.5e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 CDJ82908.1 - 0.013 15.1 0.0 0.071 12.7 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CDJ82908.1 - 0.046 13.6 0.0 0.27 11.1 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 CDJ82908.1 - 0.12 11.8 0.0 0.31 10.3 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF268 PF03269.14 CDJ82909.1 - 1.2e-12 48.1 0.0 1.5e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Caenorhabditis protein of unknown function, DUF268 IBR PF01485.21 CDJ82911.1 - 1.1e-05 25.6 6.6 1.1e-05 25.6 6.6 3.1 3 1 0 3 3 3 1 IBR domain, a half RING-finger domain TerY_C PF15616.6 CDJ82911.1 - 0.015 15.4 0.4 0.047 13.8 0.4 1.8 1 0 0 1 1 1 0 TerY-C metal binding domain IBR PF01485.21 CDJ82912.1 - 0.00017 21.8 8.5 0.00017 21.8 8.5 3.0 3 1 0 3 3 3 1 IBR domain, a half RING-finger domain WIF PF02019.18 CDJ82912.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 WIF domain Peptidase_M13 PF01431.21 CDJ82915.1 - 5.9e-68 228.5 1.1 6.8e-68 228.3 0.1 1.5 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13_N PF05649.13 CDJ82915.1 - 1.9e-10 41.0 1.2 2.2e-10 40.8 0.2 1.6 2 0 0 2 2 2 1 Peptidase family M13 DUF5638 PF18688.1 CDJ82916.1 - 0.013 15.8 0.1 2 8.8 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5638) PMBR PF09373.10 CDJ82916.1 - 0.021 15.0 0.0 0.19 11.9 0.0 2.6 2 0 0 2 2 2 0 Pseudomurein-binding repeat Mak16 PF04874.14 CDJ82916.1 - 0.17 12.5 15.8 0.059 14.0 1.5 3.4 3 1 1 4 4 4 0 Mak16 protein C-terminal region DUF3010 PF11215.8 CDJ82917.1 - 3.4e-06 27.4 9.9 1.7 8.9 0.1 5.0 5 0 0 5 5 5 3 Protein of unknown function (DUF3010) RXLR_WY PF18634.1 CDJ82917.1 - 0.00054 19.8 0.3 28 4.8 0.0 4.8 4 0 0 4 4 4 0 RXLR phytopathogen effector protein WY-domain ATC_hydrolase PF14196.6 CDJ82917.1 - 0.00061 20.6 3.2 2.2 9.0 0.1 3.6 3 0 0 3 3 3 1 L-2-amino-thiazoline-4-carboxylic acid hydrolase DUF1981 PF09324.10 CDJ82917.1 - 0.0094 15.8 0.0 38 4.2 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF1981) DUF2788 PF10981.8 CDJ82917.1 - 0.093 12.8 2.2 60 3.8 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2788) LZ_Tnp_IS66 PF13007.7 CDJ82917.1 - 0.14 12.9 3.5 3.6 8.4 0.0 3.8 4 0 0 4 4 4 0 Transposase C of IS166 homeodomain DUF2358 PF10184.9 CDJ82917.1 - 0.15 12.4 0.0 23 5.3 0.0 3.5 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2358) Hormone_6 PF00236.18 CDJ82917.1 - 0.32 11.0 0.9 1e+02 3.0 0.0 3.6 4 0 0 4 4 4 0 Glycoprotein hormone B3R PF17057.5 CDJ82917.1 - 1.3 9.3 3.8 60 3.9 0.1 3.2 3 0 0 3 3 3 0 Poxviridae B3 protein TUSC2 PF15000.6 CDJ82917.1 - 8.3 6.7 8.9 1.6e+02 2.6 0.1 4.6 5 0 0 5 5 5 0 Tumour suppressor candidate 2 Pkinase PF00069.25 CDJ82918.1 - 3.5e-73 246.2 0.0 4.5e-37 127.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ82918.1 - 1e-30 106.9 0.0 1e-17 64.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase I-set PF07679.16 CDJ82918.1 - 2e-16 59.8 0.0 4.1e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ82918.1 - 1.9e-11 44.4 0.0 4.3e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.21 CDJ82918.1 - 1e-09 38.6 0.0 2.5e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain ig PF00047.25 CDJ82918.1 - 2.3e-07 30.9 0.2 4.3e-07 30.0 0.2 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Kinase-like PF14531.6 CDJ82918.1 - 6e-07 29.1 0.0 3e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CDJ82918.1 - 2.1e-06 27.2 1.8 0.0015 17.9 0.1 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Ig_2 PF13895.6 CDJ82918.1 - 7.1e-06 26.3 0.2 2.1e-05 24.8 0.2 1.8 1 0 0 1 1 1 1 Immunoglobulin domain APH PF01636.23 CDJ82918.1 - 0.00082 19.4 0.5 0.017 15.0 0.0 2.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 CDJ82918.1 - 0.14 11.7 0.0 12 5.5 0.0 2.4 2 0 0 2 2 2 0 RIO1 family I-set PF07679.16 CDJ82919.1 - 6.6e-19 67.8 0.0 6.8e-18 64.5 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ82919.1 - 1.6e-15 57.4 0.1 2e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 CDJ82919.1 - 6.8e-08 32.7 0.0 6.1e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 CDJ82919.1 - 4.2e-07 30.1 0.0 3.9e-06 27.0 0.0 2.3 2 1 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 CDJ82919.1 - 3.6e-06 27.1 0.0 0.0002 21.5 0.0 2.2 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_C17orf99 PF17736.1 CDJ82919.1 - 0.0016 18.4 0.1 0.019 15.0 0.0 2.5 2 1 0 2 2 2 1 C17orf99 Ig domain C2-set_2 PF08205.12 CDJ82919.1 - 0.0047 17.0 0.0 0.22 11.6 0.0 2.4 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 CDJ82919.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.6 1 1 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain fn3 PF00041.21 CDJ82920.1 - 1.3e-54 182.4 10.3 4e-14 52.7 0.3 4.9 4 1 0 4 4 4 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CDJ82920.1 - 8.2e-22 77.6 6.0 1.7e-06 28.5 0.1 4.5 4 0 0 4 4 4 4 Purple acid Phosphatase, N-terminal domain Ig_3 PF13927.6 CDJ82920.1 - 1.2e-07 32.2 0.2 8.4e-07 29.5 0.0 2.6 3 0 0 3 3 3 1 Immunoglobulin domain Interfer-bind PF09294.10 CDJ82920.1 - 5e-06 26.8 0.1 2.3 8.6 0.0 4.5 5 0 0 5 5 5 2 Interferon-alpha/beta receptor, fibronectin type III I-set PF07679.16 CDJ82920.1 - 7.3e-06 26.0 0.0 2.9e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin I-set domain fn3_2 PF16893.5 CDJ82920.1 - 0.00013 22.1 0.1 0.17 12.0 0.0 3.3 3 0 0 3 3 3 1 Fibronectin type III domain fn3_4 PF16794.5 CDJ82920.1 - 0.00013 21.8 0.2 2.5 8.1 0.0 4.0 3 0 0 3 3 3 2 Fibronectin-III type domain ig PF00047.25 CDJ82920.1 - 0.00079 19.6 0.0 0.0028 17.8 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain DUF2369 PF10179.9 CDJ82920.1 - 0.0012 19.2 0.0 0.26 11.7 0.0 2.7 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2369) Ig_2 PF13895.6 CDJ82920.1 - 0.0016 18.7 0.0 0.0052 17.1 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin domain Arylsulfotran_N PF17425.2 CDJ82920.1 - 0.02 14.9 0.2 33 4.6 0.0 3.5 3 0 0 3 3 3 0 Arylsulfotransferase Ig-like domain DUF4945 PF16303.5 CDJ82920.1 - 0.045 13.7 0.1 0.48 10.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4945) Y_phosphatase PF00102.27 CDJ82921.1 - 1.1e-160 532.4 0.2 8.8e-85 284.0 0.0 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 CDJ82921.1 - 1.5e-27 95.7 7.8 1.2e-11 44.8 0.1 6.0 6 1 0 6 6 6 4 Fibronectin type III domain Y_phosphatase3 PF13350.6 CDJ82921.1 - 1.5e-07 31.6 0.0 0.0017 18.4 0.0 2.6 2 0 0 2 2 2 2 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CDJ82921.1 - 1.9e-06 28.1 0.0 0.035 14.2 0.0 2.9 2 0 0 2 2 2 2 Inositol hexakisphosphate DSPc PF00782.20 CDJ82921.1 - 1.7e-05 24.7 0.0 0.099 12.5 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Pur_ac_phosph_N PF16656.5 CDJ82921.1 - 0.00033 21.2 7.1 0.71 10.5 0.0 4.6 5 0 0 5 5 5 2 Purple acid Phosphatase, N-terminal domain PTP_tm PF18861.1 CDJ82921.1 - 0.072 13.1 0.0 0.32 11.0 0.0 2.0 3 0 0 3 3 3 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF5041 PF16444.5 CDJ82921.1 - 0.16 12.2 0.0 22 5.2 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5041) SSF PF00474.17 CDJ82923.1 - 5.5e-27 94.7 18.2 1.2e-26 93.6 18.2 1.5 1 1 0 1 1 1 1 Sodium:solute symporter family Gpi1 PF05024.15 CDJ82923.1 - 0.023 14.8 2.3 0.052 13.6 2.3 1.5 1 0 0 1 1 1 0 N-acetylglucosaminyl transferase component (Gpi1) SAC3_GANP PF03399.16 CDJ82924.1 - 3.8e-34 118.4 0.2 5.3e-34 118.0 0.2 1.1 1 0 0 1 1 1 1 SAC3/GANP family WD40 PF00400.32 CDJ82924.1 - 2.5e-05 24.9 11.4 0.013 16.4 0.3 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ82924.1 - 9.3e-05 22.7 0.5 0.027 14.7 0.1 3.5 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain RdRP_2 PF00978.21 CDJ82925.1 - 5.7e-94 315.5 0.1 7.5e-94 315.1 0.1 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Viral_helicase1 PF01443.18 CDJ82925.1 - 3.8e-06 26.8 1.1 6.3e-06 26.1 0.4 1.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase RdRP_3 PF00998.23 CDJ82925.1 - 0.0036 16.1 0.0 0.0055 15.5 0.0 1.3 1 0 0 1 1 1 1 Viral RNA dependent RNA polymerase ELO PF01151.18 CDJ82927.1 - 3.3e-56 190.6 29.2 4e-56 190.3 29.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family LPD24 PF18839.1 CDJ82927.1 - 0.11 12.7 4.7 0.23 11.7 4.7 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 24 HTH_Tnp_Tc3_2 PF01498.18 CDJ82928.1 - 2.1e-23 82.4 1.1 2.1e-23 82.4 1.1 2.0 2 0 0 2 2 1 1 Transposase DDE_3 PF13358.6 CDJ82928.1 - 8.5e-18 64.5 0.0 1.8e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 CDJ82928.1 - 3.7e-09 37.1 6.4 8.7e-08 32.7 0.8 2.7 1 1 1 2 2 2 2 Homeodomain-like domain HTH_23 PF13384.6 CDJ82928.1 - 0.00013 21.6 1.1 0.02 14.7 0.1 2.6 2 0 0 2 2 2 1 Homeodomain-like domain PAX PF00292.18 CDJ82928.1 - 0.0016 18.3 0.1 0.0028 17.6 0.1 1.4 1 0 0 1 1 1 1 'Paired box' domain MarR_2 PF12802.7 CDJ82928.1 - 0.0027 17.5 3.4 0.64 9.9 0.4 2.6 2 0 0 2 2 2 2 MarR family HTH_29 PF13551.6 CDJ82928.1 - 0.0033 17.4 2.5 0.053 13.6 0.4 2.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_24 PF13412.6 CDJ82928.1 - 0.005 16.4 3.4 1.6 8.4 1.0 3.3 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 CDJ82928.1 - 0.014 15.5 1.0 1.1 9.5 0.2 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 CDJ82928.1 - 0.022 14.5 0.8 2.2 8.0 0.1 3.0 3 1 0 3 3 3 0 Sigma-70, region 4 HTH_12 PF08461.10 CDJ82928.1 - 0.025 14.5 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_21 PF13276.6 CDJ82928.1 - 0.038 14.1 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 HTH-like domain HTH_AsnC-type PF13404.6 CDJ82928.1 - 3 7.7 4.4 7.3 6.5 2.2 2.6 2 1 0 2 2 2 0 AsnC-type helix-turn-helix domain MPM1 PF17234.2 CDJ82929.1 - 0.14 12.4 0.1 0.2 11.9 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 SPRY PF00622.28 CDJ82930.1 - 1.7e-25 89.5 0.3 3.5e-25 88.5 0.3 1.6 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 CDJ82930.1 - 3.1e-12 46.6 0.0 4.5e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain DNA_pol3_gamma3 PF12169.8 CDJ82930.1 - 0.11 12.4 0.0 0.34 10.8 0.0 1.8 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III Ice_nucleation PF00818.17 CDJ82930.1 - 0.13 12.4 0.8 0.34 11.1 0.8 1.8 1 0 0 1 1 1 0 Ice nucleation protein repeat Dus PF01207.17 CDJ82931.1 - 4.7e-45 154.0 0.1 1.2e-44 152.7 0.1 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) dsrm PF00035.26 CDJ82931.1 - 5.6e-06 27.0 0.1 1.2e-05 25.9 0.1 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif PucR PF07905.11 CDJ82931.1 - 0.029 14.7 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family His_biosynth PF00977.21 CDJ82931.1 - 0.068 12.6 0.1 0.24 10.8 0.0 1.9 2 0 0 2 2 2 0 Histidine biosynthesis protein Zf_RING PF16744.5 CDJ82931.1 - 0.16 12.1 2.4 23 5.2 0.8 3.0 3 0 0 3 3 3 0 KIAA1045 RING finger DUF4802 PF16060.5 CDJ82931.1 - 0.26 11.5 3.5 0.47 10.6 1.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4802) DUF273 PF03314.14 CDJ82932.1 - 2.2e-27 96.0 5.1 3.6e-27 95.3 5.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Glyco_transf_34 PF05637.12 CDJ82932.1 - 0.0011 18.7 0.0 0.0014 18.4 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Presenilin PF01080.17 CDJ82932.1 - 0.0051 15.6 2.4 0.0059 15.4 2.4 1.1 1 0 0 1 1 1 1 Presenilin bZIP_1 PF00170.21 CDJ82934.1 - 9.3e-12 44.9 13.1 1.3e-11 44.4 13.1 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CDJ82934.1 - 0.00019 21.5 14.5 0.00032 20.7 14.5 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CDJ82934.1 - 0.00028 21.3 9.1 0.00048 20.6 9.1 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor Atg14 PF10186.9 CDJ82934.1 - 0.08 12.0 3.4 0.11 11.5 3.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF641 PF04859.12 CDJ82934.1 - 0.17 12.2 5.8 0.25 11.7 5.8 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Bap31_Bap29_C PF18035.1 CDJ82934.1 - 0.18 11.8 3.0 0.42 10.7 3.0 1.6 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Pinin_SDK_memA PF04696.13 CDJ82934.1 - 0.99 9.5 11.5 1.5 8.8 11.5 1.2 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DUF724 PF05266.14 CDJ82934.1 - 2.7 7.8 9.1 4.2 7.2 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) 7TM_GPCR_Str PF10326.9 CDJ82935.1 - 4.4e-08 32.8 5.9 5.6e-08 32.5 5.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srh PF10318.9 CDJ82935.1 - 6.8e-08 31.9 2.3 8.1e-08 31.7 2.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Sri PF10327.9 CDJ82935.1 - 1.1e-05 24.8 3.9 1.3e-05 24.6 3.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri 7TM_GPCR_Srd PF10317.9 CDJ82935.1 - 0.00018 20.8 3.1 0.0002 20.7 3.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Srj PF10319.9 CDJ82935.1 - 0.0027 17.1 1.8 0.0032 16.9 1.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj MFS_1 PF07690.16 CDJ82936.1 - 4e-34 118.1 23.3 5.4e-34 117.7 23.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ82936.1 - 5.8e-05 22.1 12.7 0.0013 17.6 9.3 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter TB2_DP1_HVA22 PF03134.19 CDJ82937.1 - 2.6e-25 88.2 11.5 3.5e-25 87.7 11.5 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family TFB6 PF17110.5 CDJ82937.1 - 0.049 13.4 0.5 0.075 12.8 0.5 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF2306 PF10067.9 CDJ82937.1 - 0.17 12.1 1.9 0.4 10.9 1.6 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) HA2 PF04408.23 CDJ82938.1 - 7.8e-23 80.8 0.0 7.8e-23 80.8 0.0 4.2 6 1 1 7 7 5 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDJ82938.1 - 3.8e-16 59.2 0.0 9e-16 58.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDJ82938.1 - 8.3e-12 45.4 0.0 2e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ82938.1 - 1e-06 28.6 0.0 2.7e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 CDJ82938.1 - 0.00064 19.5 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDJ82938.1 - 0.00084 19.6 0.0 0.0026 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CDJ82938.1 - 0.0042 17.1 0.3 3.5 7.7 0.1 2.9 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.22 CDJ82938.1 - 0.0078 15.9 0.1 0.016 14.8 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 CDJ82938.1 - 0.0088 16.4 0.1 0.031 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 CDJ82938.1 - 0.017 14.6 0.0 0.052 13.0 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 CDJ82938.1 - 0.02 13.9 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein F-box-like PF12937.7 CDJ82938.1 - 0.03 14.2 0.0 0.22 11.4 0.1 2.3 2 0 0 2 2 2 0 F-box-like AAA_24 PF13479.6 CDJ82938.1 - 0.032 13.9 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Microtub_bd PF16796.5 CDJ82938.1 - 0.045 13.7 0.1 0.19 11.7 0.1 2.0 2 0 0 2 2 2 0 Microtubule binding Flavi_DEAD PF07652.14 CDJ82938.1 - 0.058 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain ATPase PF06745.13 CDJ82938.1 - 0.06 12.7 1.3 0.071 12.5 0.1 1.7 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 CDJ82938.1 - 0.13 11.8 0.3 0.44 10.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 CDJ82938.1 - 0.3 11.6 0.0 0.3 11.6 0.0 2.3 3 0 0 3 3 2 0 ABC transporter Fucokinase PF07959.12 CDJ82939.1 - 3.2e-20 72.4 0.0 3.9e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 L-fucokinase GYF PF02213.16 CDJ82941.1 - 1.7e-09 37.2 0.0 4.2e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 GYF domain DUF5616 PF18481.1 CDJ82941.1 - 0.0021 18.4 0.1 0.0077 16.6 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5616) GYF_2 PF14237.6 CDJ82941.1 - 0.0054 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 GYF domain 2 DUF3152 PF11350.8 CDJ82944.1 - 0.075 12.7 0.1 0.095 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) Cyd_oper_YbgE PF09600.10 CDJ82945.1 - 0.023 15.0 3.0 0.023 15.0 3.0 2.3 2 0 0 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) Kinocilin PF15033.6 CDJ82945.1 - 0.26 10.9 3.1 0.44 10.2 3.1 1.4 1 0 0 1 1 1 0 Kinocilin protein Comm PF15957.5 CDJ82945.1 - 2.1 8.7 7.4 4.5 7.6 7.4 1.7 1 1 0 1 1 1 0 Commissureless DUF3290 PF11694.8 CDJ82945.1 - 4.2 7.4 9.0 7.3 6.6 4.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) RINT1_TIP1 PF04437.13 CDJ82949.1 - 2.2e-07 30.1 0.0 2.4e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Lactamase_B PF00753.27 CDJ82950.1 - 3.1e-18 66.5 0.9 8e-16 58.6 0.9 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CDJ82950.1 - 8.4e-07 28.7 0.1 1.1e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CDJ82950.1 - 0.004 17.1 0.1 0.016 15.1 0.1 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain YflT PF11181.8 CDJ82950.1 - 0.078 13.5 0.1 4.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Heat induced stress protein YflT Suv3_N PF18114.1 CDJ82951.1 - 3.6e-40 136.7 0.0 9.8e-40 135.3 0.0 1.8 1 0 0 1 1 1 1 Suv3 helical N-terminal domain Suv3_C_1 PF18147.1 CDJ82951.1 - 7.1e-15 54.6 0.2 1.5e-14 53.6 0.2 1.6 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 SUV3_C PF12513.8 CDJ82951.1 - 7.7e-12 45.0 0.3 2.4e-11 43.4 0.3 1.9 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 CDJ82951.1 - 2.1e-10 40.9 0.0 8e-10 39.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Mg_trans_NIPA PF05653.14 CDJ82953.1 - 3.2e-54 184.0 17.5 3.7e-54 183.8 17.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA VWA PF00092.28 CDJ82955.1 - 6e-20 72.2 0.1 3.8e-16 59.8 0.0 2.5 2 1 0 2 2 2 2 von Willebrand factor type A domain Lectin_C PF00059.21 CDJ82955.1 - 1.7e-14 54.4 2.9 1.7e-14 54.4 2.9 2.3 2 1 1 3 3 3 1 Lectin C-type domain VWA_2 PF13519.6 CDJ82955.1 - 1.7e-08 35.1 2.1 1e-07 32.6 0.1 2.8 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA PF00092.28 CDJ82956.1 - 1.1e-17 64.8 0.4 1.5e-17 64.4 0.4 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Lectin_C PF00059.21 CDJ82956.1 - 3.2e-16 60.0 0.5 6.8e-16 59.0 0.5 1.5 1 0 0 1 1 1 1 Lectin C-type domain VWA_2 PF13519.6 CDJ82956.1 - 2e-08 34.9 0.1 5e-08 33.5 0.1 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain MFS_1 PF07690.16 CDJ82958.1 - 4.1e-46 157.5 23.3 4.1e-46 157.5 23.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily F-box-like PF12937.7 CDJ82959.1 - 3.3e-05 23.7 0.0 8.2e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDJ82959.1 - 0.0002 21.2 1.9 0.00029 20.6 0.2 2.2 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 CDJ82959.1 - 0.0048 16.8 0.2 0.029 14.3 0.2 2.4 2 1 0 2 2 2 1 F-box DUF4436 PF14494.6 CDJ82959.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) F-box-like PF12937.7 CDJ82960.1 - 3.8e-05 23.5 0.0 9.6e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDJ82960.1 - 0.0002 21.1 1.9 0.00034 20.4 0.2 2.3 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 CDJ82960.1 - 0.0065 16.4 0.3 0.036 13.9 0.2 2.3 2 1 0 2 2 2 1 F-box Miff PF05644.11 CDJ82961.1 - 3.3e-11 43.4 5.7 2.1e-07 30.9 0.3 2.2 1 1 1 2 2 2 2 Mitochondrial and peroxisomal fission factor Mff RVT_1 PF00078.27 CDJ82962.1 - 4.4e-15 55.8 0.0 5.3e-15 55.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ECH_1 PF00378.20 CDJ82963.1 - 4.7e-45 153.9 0.0 2.1e-44 151.7 0.0 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CDJ82963.1 - 2.1e-27 96.5 0.3 8.7e-25 87.9 0.1 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF2188 PF09954.9 CDJ82963.1 - 0.012 15.8 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) Utp13 PF08625.11 CDJ82963.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain adh_short PF00106.25 CDJ82965.1 - 4.9e-37 127.3 0.8 2.8e-36 124.8 0.3 2.1 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ82965.1 - 1e-28 100.5 1.2 2e-28 99.6 1.2 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.17 CDJ82965.1 - 5.8e-21 74.9 0.4 1.2e-20 73.9 0.4 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family KR PF08659.10 CDJ82965.1 - 7.3e-07 29.3 0.7 1.5e-06 28.2 0.3 1.7 2 0 0 2 2 2 1 KR domain Alkyl_sulf_C PF14864.6 CDJ82965.1 - 3.8e-05 24.0 0.2 7e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal NAD_binding_2 PF03446.15 CDJ82965.1 - 0.037 14.2 0.2 0.089 13.0 0.2 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_3 PF03447.16 CDJ82965.1 - 0.044 14.4 5.4 0.38 11.4 0.1 3.2 3 1 0 4 4 4 0 Homoserine dehydrogenase, NAD binding domain SCP2_2 PF13530.6 CDJ82965.1 - 0.055 13.9 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Sterol carrier protein domain CUE PF02845.16 CDJ82966.1 - 2.8e-05 23.7 0.0 3.3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 CUE domain RVT_1 PF00078.27 CDJ82967.1 - 1.9e-08 34.1 0.0 2.5e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TIMP PF00965.17 CDJ82968.1 - 1.4e-18 67.4 0.0 1.7e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.21 CDJ82968.1 - 1.4e-08 34.4 0.0 2.1e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 UNC-6/NTR/C345C module TIMP PF00965.17 CDJ82969.1 - 3.5e-20 72.6 0.0 4.2e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.21 CDJ82969.1 - 0.0016 18.2 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Tenui_PVC2 PF06656.11 CDJ82969.1 - 0.022 12.7 0.1 0.025 12.5 0.1 1.0 1 0 0 1 1 1 0 Tenuivirus PVC2 protein PAM2 PF07145.15 CDJ82970.1 - 0.009 15.6 0.6 0.022 14.4 0.6 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Thioredoxin PF00085.20 CDJ82972.1 - 3.5e-87 287.1 0.1 2.5e-30 104.5 0.0 3.6 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 CDJ82972.1 - 6.4e-33 114.2 10.8 8.4e-20 71.5 5.3 4.1 2 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CDJ82972.1 - 5.9e-17 62.1 5.1 0.00016 22.1 0.2 5.8 4 2 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CDJ82972.1 - 7.4e-13 48.6 6.2 0.0023 18.2 0.0 6.7 6 3 2 8 8 7 3 Thioredoxin-like OST3_OST6 PF04756.13 CDJ82972.1 - 6e-11 42.2 0.9 0.0091 15.4 0.0 4.6 4 1 1 5 5 5 3 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CDJ82972.1 - 7.3e-10 38.9 0.0 0.00015 21.8 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin-like Calsequestrin PF01216.17 CDJ82972.1 - 1.5e-09 37.4 1.7 2.5e-09 36.7 1.3 1.6 1 1 0 1 1 1 1 Calsequestrin AhpC-TSA PF00578.21 CDJ82972.1 - 2e-07 31.0 1.6 0.0066 16.4 0.0 3.8 4 1 1 5 5 5 2 AhpC/TSA family Thioredoxin_3 PF13192.6 CDJ82972.1 - 2.9e-07 30.4 0.0 0.11 12.5 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin domain TraF PF13728.6 CDJ82972.1 - 4.3e-07 30.0 0.0 0.65 9.8 0.0 3.5 3 0 0 3 3 3 3 F plasmid transfer operon protein HyaE PF07449.11 CDJ82972.1 - 7.5e-07 29.1 0.1 0.86 9.6 0.0 4.2 4 0 0 4 4 4 2 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.6 CDJ82972.1 - 0.00018 21.7 8.7 0.096 12.8 0.1 5.5 4 2 2 6 6 6 1 Thioredoxin Redoxin PF08534.10 CDJ82972.1 - 0.0004 20.1 2.3 1.1 9.0 0.0 3.5 4 0 0 4 4 4 2 Redoxin DSBA PF01323.20 CDJ82972.1 - 0.0039 17.0 0.7 16 5.2 0.1 4.7 4 2 2 6 6 6 0 DSBA-like thioredoxin domain DUF836 PF05768.14 CDJ82972.1 - 0.0076 16.6 0.0 8.2 6.9 0.0 3.2 3 0 0 3 3 3 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 CDJ82972.1 - 0.019 15.2 9.4 1.8 8.9 0.2 5.4 4 2 0 4 4 4 0 Glutaredoxin OTU PF02338.19 CDJ82973.1 - 3.2e-19 69.7 0.0 6.4e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CDJ82973.1 - 1.6e-05 24.5 1.9 0.016 14.7 0.0 2.5 3 0 0 3 3 3 2 Peptidase C65 Otubain Yippee-Mis18 PF03226.14 CDJ82974.1 - 7.3e-10 39.0 0.1 8.7e-10 38.8 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Yippee-Mis18 PF03226.14 CDJ82975.1 - 3.9e-12 46.3 0.1 5.2e-12 45.9 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-AD PF07776.15 CDJ82975.1 - 0.022 15.0 0.2 0.047 13.9 0.2 1.5 1 1 0 1 1 1 0 Zinc-finger associated domain (zf-AD) Endonuclease_7 PF02945.15 CDJ82975.1 - 0.028 14.3 0.3 0.41 10.6 0.0 2.1 2 0 0 2 2 2 0 Recombination endonuclease VII Rsm1 PF08600.10 CDJ82975.1 - 0.039 14.1 0.7 0.15 12.2 0.1 2.0 2 0 0 2 2 2 0 Rsm1-like zf-BED PF02892.15 CDJ82975.1 - 0.27 11.3 2.9 10 6.2 0.1 2.5 2 0 0 2 2 2 0 BED zinc finger HSP20 PF00011.21 CDJ82976.1 - 1.7e-14 53.8 0.0 2.1e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ82976.1 - 4.7e-05 22.9 0.0 6.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA fn3 PF00041.21 CDJ82979.1 - 1.8e-13 50.6 11.8 1.2e-07 32.0 1.5 3.5 3 1 0 3 3 3 2 Fibronectin type III domain DUF5620 PF18522.1 CDJ82979.1 - 0.062 13.7 0.2 14 6.1 0.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF5620) DUF4236 PF14020.6 CDJ82979.1 - 0.44 11.2 4.4 0.61 10.7 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4236) DUF4234 PF14018.6 CDJ82980.1 - 0.012 15.7 0.0 0.31 11.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) DUF4519 PF15012.6 CDJ82980.1 - 0.022 14.9 0.6 0.6 10.3 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) DUF4381 PF14316.6 CDJ82980.1 - 0.037 14.3 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) VirB8 PF04335.13 CDJ82980.1 - 0.096 12.5 0.3 0.15 11.9 0.3 1.3 1 0 0 1 1 1 0 VirB8 protein zf-C3HC4_4 PF15227.6 CDJ82981.1 - 2.7e-08 33.8 3.0 2.7e-08 33.8 3.0 3.0 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 CDJ82981.1 - 2e-07 30.8 1.9 2e-07 30.8 1.9 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ82981.1 - 4.8e-07 29.7 3.1 4.8e-07 29.7 3.1 2.8 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDJ82981.1 - 1.7e-06 27.8 3.7 1.7e-06 27.8 3.7 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ82981.1 - 4.1e-06 26.7 2.8 4.1e-06 26.7 2.8 3.4 4 0 0 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.6 CDJ82981.1 - 2.5e-05 24.5 4.4 2.5e-05 24.5 4.4 3.0 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDJ82981.1 - 0.00022 21.0 3.1 0.00022 21.0 3.1 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 CDJ82981.1 - 0.011 15.5 1.7 0.017 15.0 0.2 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Fzo_mitofusin PF04799.13 CDJ82982.1 - 0.026 14.1 0.1 0.045 13.3 0.1 1.3 1 0 0 1 1 1 0 fzo-like conserved region GAGE PF05831.11 CDJ82982.1 - 5.1 7.7 6.6 0.65 10.6 0.8 2.4 2 1 1 3 3 3 0 GAGE protein TMEM70 PF06979.12 CDJ82983.1 - 4.3e-18 66.0 4.7 7.2e-18 65.3 4.6 1.4 1 1 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex TEBP_beta PF07404.11 CDJ82983.1 - 0.14 11.5 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) Collagen PF01391.18 CDJ82984.1 - 2.4e-21 75.3 78.8 4.3e-10 39.2 20.5 4.5 3 1 1 4 4 4 3 Collagen triple helix repeat (20 copies) Motile_Sperm PF00635.26 CDJ82985.1 - 2.2e-19 69.3 0.0 2.9e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Apt1 PF10351.9 CDJ82985.1 - 0.0046 15.9 8.1 0.0041 16.0 8.1 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ82985.1 - 0.2 10.4 4.0 0.23 10.2 4.0 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 CDJ82985.1 - 0.9 8.3 12.7 1.1 8.0 12.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Dsh_C PF12316.8 CDJ82985.1 - 9.6 6.5 19.9 14 6.1 19.9 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Gp-FAR-1 PF05823.12 CDJ82986.1 - 1e-16 61.6 2.2 1.4e-16 61.2 2.2 1.1 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) p450 PF00067.22 CDJ82986.1 - 0.0078 15.0 0.1 0.015 14.1 0.1 1.3 1 1 0 1 1 1 1 Cytochrome P450 RdRP PF05183.12 CDJ82986.1 - 0.026 13.2 0.1 0.026 13.2 0.1 1.0 1 0 0 1 1 1 0 RNA dependent RNA polymerase Sigma70_r4 PF04545.16 CDJ82986.1 - 0.028 14.0 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 DUF520 PF04461.13 CDJ82986.1 - 0.031 14.4 0.1 0.057 13.5 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF520) DUF4404 PF14357.6 CDJ82986.1 - 0.033 14.8 1.0 0.32 11.7 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) Gal-bind_lectin PF00337.22 CDJ82987.1 - 6.8e-55 184.3 1.6 2.6e-28 98.2 0.1 2.1 2 0 0 2 2 2 2 Galactoside-binding lectin Alginate_lyase2 PF08787.11 CDJ82987.1 - 0.00052 19.9 0.2 0.12 12.2 0.0 2.2 2 0 0 2 2 2 2 Alginate lyase OLF PF02191.16 CDJ82987.1 - 0.15 11.6 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Olfactomedin-like domain Trypan_PARP PF05887.11 CDJ82988.1 - 0.048 13.6 12.2 0.093 12.7 12.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PPP4R2 PF09184.11 CDJ82988.1 - 2.2 7.8 19.3 3 7.4 19.3 1.2 1 0 0 1 1 1 0 PPP4R2 SAPS PF04499.15 CDJ82988.1 - 4 6.1 7.9 4.7 5.9 7.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.22 CDJ82988.1 - 7.2 5.7 7.4 11 5.1 7.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BUD22 PF09073.10 CDJ82988.1 - 8.7 5.6 25.7 11 5.2 25.7 1.1 1 0 0 1 1 1 0 BUD22 AMP-binding PF00501.28 CDJ82989.1 - 3.6e-80 269.6 0.2 7.6e-77 258.7 0.2 2.0 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ82989.1 - 5.3e-20 72.2 0.1 1.9e-19 70.4 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PH PF00169.29 CDJ82990.1 - 1.1e-10 41.9 0.9 2.9e-10 40.6 0.3 2.0 2 0 0 2 2 2 1 PH domain PH_17 PF18012.1 CDJ82990.1 - 0.0015 18.2 0.0 0.0041 16.8 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 CDJ82990.1 - 0.006 17.0 0.5 0.015 15.7 0.5 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 CDJ82990.1 - 0.29 11.6 6.8 0.13 12.7 1.9 2.7 2 2 0 2 2 2 0 Pleckstrin homology domain zf-RING_9 PF13901.6 CDJ82992.1 - 7.3e-58 196.0 6.0 1.4e-57 195.0 6.0 1.5 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon RUN PF02759.19 CDJ82992.1 - 1.1e-22 80.4 0.0 2.4e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 RUN domain Zf_RING PF16744.5 CDJ82992.1 - 0.029 14.5 5.7 0.098 12.8 5.7 1.9 1 0 0 1 1 1 0 KIAA1045 RING finger zinc_ribbon_10 PF10058.9 CDJ82992.1 - 6.2 6.6 9.0 2.8 7.7 2.7 2.9 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein EMP24_GP25L PF01105.24 CDJ82993.1 - 2.4e-42 144.9 0.0 2.7e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MFS_1 PF07690.16 CDJ82994.1 - 7.9e-34 117.1 53.6 2.4e-31 108.9 36.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CDJ82994.1 - 1.3e-08 34.2 28.7 5.7e-07 28.7 28.7 3.1 1 1 0 1 1 1 1 MFS_1 like family Nrap_D5 PF17406.2 CDJ82995.1 - 6e-31 107.4 0.5 2.5e-30 105.4 0.1 2.2 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 CDJ82995.1 - 3.7e-26 91.8 0.0 7.2e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 CDJ82995.1 - 1.4e-22 80.5 0.1 2.8e-22 79.5 0.1 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 CDJ82995.1 - 4.2e-20 72.3 0.0 9.3e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 6 Nrap PF03813.14 CDJ82995.1 - 5e-18 65.6 0.0 1e-17 64.6 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D2 PF17403.2 CDJ82995.1 - 2.2e-13 50.2 0.1 3.4e-09 36.7 0.0 2.5 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Snurportin1 PF11538.8 CDJ82995.1 - 1.4e-10 41.2 7.0 3e-10 40.1 7.0 1.6 1 0 0 1 1 1 1 Snurportin1 DUF1043 PF06295.12 CDJ82995.1 - 0.07 13.1 0.4 0.22 11.6 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) 30K_MP_C_Ter PF11330.8 CDJ82997.1 - 0.087 12.1 1.2 0.098 12.0 1.2 1.1 1 0 0 1 1 1 0 C-Terminal of 30K viral movement proteins Sre PF03125.18 CDJ82998.1 - 2.8e-35 122.2 26.6 1.2e-34 120.0 26.6 1.8 1 1 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor Acetyltransf_1 PF00583.25 CDJ82998.1 - 2.4e-15 56.8 0.0 4.5e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDJ82998.1 - 5.1e-12 45.8 0.0 1.6e-11 44.2 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDJ82998.1 - 4.5e-11 43.0 0.0 9.5e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDJ82998.1 - 5.1e-11 42.4 0.0 1.2e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 CDJ82998.1 - 7.1e-06 26.1 0.0 1.4e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain 7TM_GPCR_Srab PF10292.9 CDJ82998.1 - 2.5e-05 23.4 24.4 0.00018 20.6 23.8 2.4 2 1 0 2 2 2 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor Acetyltransf_15 PF17013.5 CDJ82998.1 - 0.00017 21.2 0.4 0.0003 20.3 0.1 1.5 2 0 0 2 2 2 1 Putative acetyl-transferase Acetyltransf_4 PF13420.7 CDJ82998.1 - 0.001 19.3 0.0 0.0019 18.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CDJ82998.1 - 0.0024 18.6 0.0 0.0044 17.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CDJ82998.1 - 0.011 15.4 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.10 CDJ82998.1 - 0.018 15.2 0.0 0.12 12.6 0.0 2.2 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Acetyltransf_13 PF13880.6 CDJ82998.1 - 0.037 14.0 0.0 0.086 12.8 0.0 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Forkhead PF00250.18 CDJ82999.1 - 6.7e-18 64.7 0.0 1.1e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain Sec2p PF06428.11 CDJ83000.1 - 0.019 14.9 0.7 0.039 13.9 0.7 1.5 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p PI3K_P85_iSH2 PF16454.5 CDJ83000.1 - 0.036 13.7 2.9 0.041 13.5 0.9 1.9 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain CENP-F_leu_zip PF10473.9 CDJ83000.1 - 0.095 12.7 2.3 0.24 11.4 2.3 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NOT2_3_5 PF04153.18 CDJ83001.1 - 5.1e-27 94.5 0.1 7.5e-27 94.0 0.1 1.2 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family zf-rbx1 PF12678.7 CDJ83002.1 - 1.5e-21 76.4 16.6 2.1e-21 76.0 16.6 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CDJ83002.1 - 9.8e-17 60.8 15.9 1.2e-16 60.5 15.9 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CDJ83002.1 - 3.2e-09 37.0 12.9 3.2e-09 37.0 12.9 2.2 1 1 2 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ83002.1 - 0.00086 19.1 19.4 0.011 15.6 18.7 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ83002.1 - 0.004 17.0 16.4 0.017 15.0 16.4 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ83002.1 - 0.011 15.5 11.7 0.011 15.5 11.7 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3421 PF11901.8 CDJ83002.1 - 0.049 13.6 0.1 0.065 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3421) zf-RING_5 PF14634.6 CDJ83002.1 - 0.89 9.6 19.3 2.6 8.1 17.5 2.1 1 1 1 2 2 2 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CDJ83002.1 - 1.2 8.8 21.0 0.35 10.5 13.2 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type Y_phosphatase PF00102.27 CDJ83004.1 - 4.7e-59 199.8 0.2 7.4e-59 199.2 0.2 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ83004.1 - 0.058 13.2 0.1 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain DUF4199 PF13858.6 CDJ83005.1 - 0.0029 18.0 0.0 0.18 12.2 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF4199) RVT_1 PF00078.27 CDJ83006.1 - 2e-07 30.8 0.0 2.9e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) F-box-like PF12937.7 CDJ83008.1 - 1.5e-15 56.8 0.6 4.5e-15 55.3 0.6 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDJ83008.1 - 1.3e-11 44.0 0.4 5.3e-11 42.1 0.4 2.2 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 CDJ83008.1 - 0.00097 19.0 0.1 0.0061 16.4 0.0 2.2 2 0 0 2 2 2 1 F-box LRR_4 PF12799.7 CDJ83008.1 - 0.0019 18.6 11.7 13 6.4 0.0 7.1 5 2 4 10 10 10 3 Leucine Rich repeats (2 copies) SapB_2 PF03489.17 CDJ83009.1 - 6.1e-09 35.8 0.2 6.1e-09 35.8 0.2 1.7 2 0 0 2 2 2 1 Saposin-like type B, region 2 SapB_1 PF05184.15 CDJ83009.1 - 6.3 6.9 10.1 0.52 10.4 2.4 3.0 3 1 0 3 3 3 0 Saposin-like type B, region 1 SapB_2 PF03489.17 CDJ83010.1 - 3e-10 40.0 1.2 5.1e-10 39.3 1.2 1.4 1 0 0 1 1 1 1 Saposin-like type B, region 2 CxC7 PF18866.1 CDJ83010.1 - 0.02 15.0 0.2 0.88 9.8 0.1 2.1 2 0 0 2 2 2 0 CxC7 like cysteine cluster associated with KDZ transposases U83 PF17465.2 CDJ83010.1 - 0.072 13.2 0.1 0.64 10.2 0.1 2.0 1 1 1 2 2 2 0 Chemokine-like protein, HHV-6 U83 gene product zf-C2H2 PF00096.26 CDJ83011.1 - 5.8e-13 48.5 27.8 0.00017 21.9 3.5 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ83011.1 - 5.1e-10 39.3 8.5 5.2e-07 29.8 1.3 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDJ83011.1 - 1.2e-06 28.8 25.8 0.0063 17.3 3.4 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 CDJ83011.1 - 0.0027 18.3 7.7 0.029 15.0 1.3 3.0 1 1 1 2 2 2 1 FOXP coiled-coil domain IBR PF01485.21 CDJ83011.1 - 0.058 13.6 4.1 2.5 8.4 4.1 2.5 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain DUF212 PF02681.14 CDJ83011.1 - 0.081 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Divergent PAP2 family HTH_18 PF12833.7 CDJ83011.1 - 0.097 13.0 1.6 57 4.1 0.0 3.8 3 0 0 3 3 3 0 Helix-turn-helix domain zf-C2H2_jaz PF12171.8 CDJ83011.1 - 0.11 12.9 2.9 6.6 7.2 0.3 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding HMGL-like PF00682.19 CDJ83011.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 HMGL-like zf-C2HE PF16278.5 CDJ83011.1 - 0.97 9.9 5.6 1.2 9.7 0.6 2.8 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 CDJ83011.1 - 1.6 8.5 15.5 1.1 9.1 0.1 4.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain NAD_binding_10 PF13460.6 CDJ83012.1 - 1.2e-09 38.3 0.0 1.8e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CDJ83012.1 - 1.3e-09 37.9 0.0 2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CDJ83012.1 - 2.9e-08 33.1 0.0 1.4e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CDJ83012.1 - 4.1e-06 26.1 0.0 1.1e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 CDJ83012.1 - 0.0004 20.0 0.0 0.00062 19.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 CDJ83012.1 - 0.00045 19.5 0.0 2.7 7.1 0.0 3.1 2 1 1 3 3 3 2 Male sterility protein adh_short PF00106.25 CDJ83012.1 - 0.077 12.5 0.0 0.16 11.4 0.0 1.4 1 1 0 1 1 1 0 short chain dehydrogenase VWA PF00092.28 CDJ83014.1 - 2.4e-34 119.1 0.2 6.2e-34 117.7 0.2 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CDJ83014.1 - 8.6e-12 45.7 0.0 3.4e-11 43.7 0.0 2.1 1 0 0 1 1 1 1 von Willebrand factor type A domain CYSTM PF12734.7 CDJ83017.1 - 2.3e-05 24.6 7.1 2.3e-05 24.6 7.1 4.0 3 1 0 3 3 3 1 Cysteine-rich TM module stress tolerance Pex14_N PF04695.13 CDJ83017.1 - 0.43 11.2 2.9 0.47 11.1 2.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MADF_DNA_bdg PF10545.9 CDJ83018.1 - 1.6e-15 57.2 0.7 2.8e-15 56.4 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 CDJ83018.1 - 0.00012 22.4 0.4 0.00027 21.3 0.4 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain BESS PF02944.20 CDJ83018.1 - 0.32 10.9 1.1 0.48 10.3 0.1 1.8 2 0 0 2 2 2 0 BESS motif MFS_1 PF07690.16 CDJ83019.1 - 2e-32 112.5 41.4 8e-30 103.9 30.8 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily OATP PF03137.20 CDJ83019.1 - 2.1 6.5 7.7 0.12 10.6 1.1 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Carn_acyltransf PF00755.20 CDJ83020.1 - 1e-149 499.9 0.0 1.2e-149 499.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Isochorismatase PF00857.20 CDJ83021.1 - 1.1e-22 81.0 0.0 1.8e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family F-actin_cap_A PF01267.17 CDJ83023.1 - 3.2e-46 157.9 0.7 1e-22 80.8 0.0 2.0 1 1 1 2 2 2 2 F-actin capping protein alpha subunit FARP PF01581.16 CDJ83024.1 - 6.3e-10 37.8 0.0 29 5.8 0.0 6.5 6 0 0 6 6 6 5 FMRFamide related peptide family IBR PF01485.21 CDJ83026.1 - 1.9e-20 72.9 48.5 1.6e-15 57.0 6.5 4.2 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 CDJ83026.1 - 0.00031 20.5 2.3 0.00031 20.5 2.3 5.2 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ83026.1 - 0.0014 18.4 6.7 0.0014 18.4 6.7 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Chromo PF00385.24 CDJ83027.1 - 1.1e-11 44.5 0.2 3.7e-11 42.8 0.2 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Dynamin_M PF01031.20 CDJ83028.1 - 3.8e-115 384.0 1.5 3.5e-98 328.3 0.0 2.6 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 CDJ83028.1 - 2.3e-52 177.4 0.2 7.6e-52 175.8 0.0 2.0 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 CDJ83028.1 - 2.3e-52 175.1 19.0 5.7e-28 96.9 5.4 2.8 2 0 0 2 2 2 2 Dynamin GTPase effector domain CDPS PF16715.5 CDJ83028.1 - 4.9e-05 23.1 3.5 0.082 12.5 0.4 2.3 2 0 0 2 2 2 2 Cyclodipeptide synthase MMR_HSR1 PF01926.23 CDJ83028.1 - 5.4e-05 23.2 0.2 0.00044 20.3 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase CelTOS PF18659.1 CDJ83028.1 - 0.0046 17.4 7.6 4.6 7.7 0.6 4.5 3 1 0 3 3 3 2 Cell-traversal protein for ookinetes and sporozoites AAA_16 PF13191.6 CDJ83028.1 - 0.013 15.9 1.2 7.3 6.9 0.0 3.7 4 0 0 4 4 4 0 AAA ATPase domain DUF4093 PF13331.6 CDJ83028.1 - 0.03 14.7 1.9 11 6.5 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4093) PH_RBD PF12068.8 CDJ83028.1 - 0.061 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Rab-binding domain (RBD) LRRFIP PF09738.9 CDJ83028.1 - 0.074 12.5 10.3 0.13 11.8 1.3 2.4 2 0 0 2 2 2 0 LRRFIP family AAA_28 PF13521.6 CDJ83028.1 - 0.09 13.0 0.1 0.55 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF3271 PF11675.8 CDJ83028.1 - 0.16 11.2 1.6 11 5.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3271) Snurportin1 PF11538.8 CDJ83028.1 - 0.32 11.2 4.8 8.5 6.7 1.0 2.7 2 0 0 2 2 2 0 Snurportin1 OmpH PF03938.14 CDJ83028.1 - 3 8.2 8.1 1.4 9.3 0.7 3.1 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Arfaptin PF06456.13 CDJ83029.1 - 2e-36 125.7 0.9 2.4e-36 125.4 0.2 1.4 2 0 0 2 2 2 1 Arfaptin-like domain PDZ PF00595.24 CDJ83029.1 - 3e-10 40.3 0.2 5.7e-10 39.4 0.2 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDJ83029.1 - 1.5e-09 37.6 0.1 2.5e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ83029.1 - 1e-05 25.8 0.3 2.4e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PT-HINT PF07591.11 CDJ83029.1 - 0.032 14.5 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 Pretoxin HINT domain Tricorn_PDZ PF14685.6 CDJ83029.1 - 0.095 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Tricorn protease PDZ domain GRASP55_65 PF04495.14 CDJ83029.1 - 0.14 12.5 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain RVT_1 PF00078.27 CDJ83030.1 - 2.8e-36 125.1 0.0 3.8e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5499 PF17603.2 CDJ83030.1 - 0.29 11.8 1.7 2 9.1 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5499) MOR2-PAG1_N PF14222.6 CDJ83031.1 - 1.7e-146 489.5 0.4 2.9e-146 488.7 0.4 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 CDJ83031.1 - 8.1e-39 134.0 0.7 8.1e-39 134.0 0.7 2.4 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 CDJ83031.1 - 9e-09 33.6 3.5 0.0022 15.7 0.1 3.5 2 1 0 3 3 3 3 Cell morphogenesis central region Zona_pellucida PF00100.23 CDJ83032.1 - 1.6e-18 67.4 9.5 2.3e-18 66.9 9.5 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain COX6A PF02046.15 CDJ83034.1 - 2.3e-12 47.4 0.0 3.9e-12 46.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIa DEAD PF00270.29 CDJ83035.1 - 1.3e-27 96.7 0.3 5.5e-27 94.7 0.3 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ83035.1 - 4e-12 46.5 0.8 1.4e-11 44.7 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDJ83035.1 - 1.8e-08 34.7 0.0 1.2e-06 28.8 0.0 3.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDJ83035.1 - 0.00022 21.5 0.3 0.00081 19.7 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ83035.1 - 0.0017 18.1 0.3 0.0048 16.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CDJ83035.1 - 0.0065 15.6 0.0 0.24 10.4 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 CDJ83035.1 - 0.01 16.2 0.2 0.022 15.1 0.2 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CDJ83035.1 - 0.019 14.7 0.1 0.2 11.4 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_11 PF13086.6 CDJ83035.1 - 0.069 12.9 1.0 2 8.1 0.0 3.1 3 1 1 4 4 4 0 AAA domain DUF4558 PF15104.6 CDJ83035.1 - 0.42 10.7 7.5 2.3 8.3 7.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4558) AAA_23 PF13476.6 CDJ83035.1 - 1.5 9.3 0.0 1.5 9.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sec63 PF02889.16 CDJ83036.1 - 4.6e-116 386.5 1.6 7.4e-61 205.5 0.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CDJ83036.1 - 7e-23 81.3 0.0 2.8e-22 79.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ83036.1 - 2e-10 40.9 0.0 4.7e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDJ83036.1 - 3.8e-07 30.4 0.0 1.6e-06 28.4 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ig_3 PF13927.6 CDJ83037.1 - 1.6e-56 188.8 8.3 1.1e-10 41.9 0.0 6.8 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 CDJ83037.1 - 1.3e-49 166.2 1.4 5e-11 42.5 0.1 6.7 6 0 0 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.6 CDJ83037.1 - 3e-47 158.8 4.5 2e-09 37.6 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin domain fn3 PF00041.21 CDJ83037.1 - 2.2e-42 143.3 14.4 2.3e-08 34.2 0.0 8.1 7 2 0 7 7 7 5 Fibronectin type III domain ig PF00047.25 CDJ83037.1 - 5.7e-33 113.0 4.2 2.9e-06 27.4 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin domain Bravo_FIGEY PF13882.6 CDJ83037.1 - 6.7e-18 65.8 2.7 1.8e-17 64.4 2.7 1.8 1 0 0 1 1 1 1 Bravo-like intracellular region V-set PF07686.17 CDJ83037.1 - 2.9e-14 53.1 12.7 0.038 14.2 0.1 10.0 7 5 2 10 10 10 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDJ83037.1 - 1.6e-12 47.3 0.2 0.0068 16.5 0.0 4.8 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain Pur_ac_phosph_N PF16656.5 CDJ83037.1 - 2.9e-06 27.8 9.2 1.3 9.7 0.1 6.3 6 0 0 6 6 6 1 Purple acid Phosphatase, N-terminal domain DUF2207 PF09972.9 CDJ83037.1 - 8.7e-05 21.5 0.0 0.00016 20.6 0.0 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) TMEM52 PF14979.6 CDJ83037.1 - 0.0015 18.5 0.7 0.0048 16.8 0.7 1.8 1 0 0 1 1 1 1 Transmembrane 52 RCR PF12273.8 CDJ83037.1 - 0.0069 17.0 0.0 0.036 14.7 0.0 2.3 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red fn3_2 PF16893.5 CDJ83037.1 - 0.0073 16.4 0.0 0.035 14.2 0.0 2.1 2 0 0 2 2 2 1 Fibronectin type III domain Izumo-Ig PF16706.5 CDJ83037.1 - 0.019 15.0 0.0 1.9 8.6 0.0 3.7 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain WBP-1 PF11669.8 CDJ83037.1 - 0.024 15.2 0.1 0.067 13.8 0.1 1.7 1 0 0 1 1 1 0 WW domain-binding protein 1 Herpes_gE PF02480.16 CDJ83037.1 - 0.062 12.0 0.0 0.16 10.7 0.0 1.6 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Ig_C17orf99 PF17736.1 CDJ83037.1 - 0.085 12.9 0.1 38 4.4 0.0 4.1 3 0 0 3 3 3 0 C17orf99 Ig domain Ig_6 PF18452.1 CDJ83037.1 - 0.15 11.6 0.0 1.7 8.3 0.0 2.8 3 0 0 3 3 3 0 Immunoglobulin domain AAA_12 PF13087.6 CDJ83039.1 - 1.4e-36 126.0 0.0 2e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CDJ83039.1 - 3.4e-05 23.7 0.0 0.0023 17.7 0.0 2.1 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase UvrD_C PF13361.6 CDJ83039.1 - 0.012 15.0 0.0 0.047 13.1 0.0 1.7 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain Homeodomain PF00046.29 CDJ83040.1 - 0.1 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Homeodomain DUF1759 PF03564.15 CDJ83043.1 - 2.7e-23 82.6 3.1 4.5e-23 81.8 2.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) LXG PF04740.12 CDJ83043.1 - 0.072 12.8 3.7 0.11 12.2 2.0 2.1 2 0 0 2 2 2 0 LXG domain of WXG superfamily BLOC1_2 PF10046.9 CDJ83043.1 - 0.15 12.3 4.0 1 9.7 0.0 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YtxH PF12732.7 CDJ83043.1 - 0.85 10.2 2.6 6.8 7.3 0.3 3.1 3 1 0 3 3 3 0 YtxH-like protein ZapB PF06005.12 CDJ83043.1 - 1.2 9.7 13.0 4.7 7.7 0.2 3.4 3 1 0 3 3 3 0 Cell division protein ZapB mTERF PF02536.14 CDJ83044.1 - 3.9e-09 35.9 0.0 8.5e-09 34.8 0.0 1.5 1 1 0 1 1 1 1 mTERF Adap_comp_sub PF00928.21 CDJ83045.1 - 2.8e-90 302.3 0.1 4.1e-90 301.7 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CDJ83045.1 - 1.3e-08 34.9 1.5 2.3e-08 34.1 1.5 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Creatinase_N_2 PF16189.5 CDJ83046.1 - 8.4e-80 266.5 0.0 5.2e-40 137.2 0.0 3.6 4 1 1 5 5 5 2 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 CDJ83046.1 - 2.5e-58 197.2 1.5 9.1e-36 123.5 0.0 3.3 2 1 1 3 3 3 3 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 CDJ83046.1 - 1.2e-33 114.9 0.0 1.3e-22 79.6 0.0 2.8 2 0 0 2 2 2 2 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 CDJ83046.1 - 2.4e-25 89.7 0.2 4.2e-10 40.4 0.0 4.7 4 0 0 4 4 4 4 Creatinase/Prolidase N-terminal domain DNA_pol_E_B PF04042.16 CDJ83048.1 - 4.4e-33 114.4 0.0 5.9e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 CDJ83048.1 - 1.7e-26 92.9 0.3 2.4e-26 92.4 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain IPK PF03770.16 CDJ83049.1 - 5.1e-13 49.3 0.0 7.3e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Stork_head PF10264.9 CDJ83050.1 - 1.2e-20 73.5 0.3 1.2e-20 73.5 0.3 1.8 2 0 0 2 2 2 1 Winged helix Storkhead-box1 domain Thyroglobulin_1 PF00086.18 CDJ83051.1 - 5.1e-29 99.7 26.7 2.4e-10 39.9 0.3 5.0 3 1 1 4 4 4 3 Thyroglobulin type-1 repeat Lustrin_cystein PF14625.6 CDJ83051.1 - 4.8e-24 84.5 54.2 9.4e-10 38.7 6.6 16.9 15 3 5 20 20 20 5 Lustrin, cysteine-rich repeated domain WAP PF00095.21 CDJ83051.1 - 6.6e-22 77.6 77.4 1.5e-08 34.9 17.8 14.2 10 4 2 12 12 12 4 WAP-type (Whey Acidic Protein) 'four-disulfide core' Antistasin PF02822.14 CDJ83051.1 - 1.5e-05 25.6 9.4 1.5e-05 25.6 9.4 14.7 19 1 0 19 19 19 3 Antistasin family WAP PF00095.21 CDJ83052.1 - 0.0091 16.4 3.6 0.013 15.9 3.6 1.2 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' PAN_3 PF08277.12 CDJ83052.1 - 0.18 11.6 3.9 0.27 11.1 3.9 1.3 1 1 0 1 1 1 0 PAN-like domain Gly-zipper_OmpA PF13436.6 CDJ83053.1 - 0.012 15.4 0.9 0.02 14.7 0.9 1.4 1 0 0 1 1 1 0 Glycine-zipper domain Gly-zipper_YMGG PF13441.6 CDJ83053.1 - 0.02 14.6 1.0 0.025 14.3 1.0 1.2 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF5488 PF17590.2 CDJ83053.1 - 2.8 7.7 7.5 0.23 11.2 0.6 2.3 1 1 0 2 2 2 0 Family of unknown function (DUF5488) SCVP PF17619.2 CDJ83054.1 - 1.8e-110 362.1 21.7 8.2e-24 84.3 0.1 6.2 5 1 1 6 6 6 6 Secreted clade V proteins DUF3439 PF11921.8 CDJ83054.1 - 4.5e-06 26.6 32.8 0.00067 19.6 8.5 5.4 5 0 0 5 5 5 2 Domain of unknown function (DUF3439) DUF1473 PF07341.11 CDJ83054.1 - 0.0014 18.5 5.6 1.2 8.9 0.2 3.6 3 0 0 3 3 3 3 Protein of unknown function (DUF1473) KCNQ2_u3 PF16642.5 CDJ83054.1 - 0.15 13.1 8.2 1.1 10.2 1.3 3.5 3 0 0 3 3 3 0 Unstructured region on Potassium channel subunit alpha KvLQT2 tRNA_bind_2 PF13725.6 CDJ83054.1 - 1 9.0 7.2 30 4.2 0.2 4.4 5 0 0 5 5 5 0 Possible tRNA binding domain Sporozoite_P67 PF05642.11 CDJ83054.1 - 1.4 6.9 10.3 0.022 12.9 2.0 1.9 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Mucin PF01456.17 CDJ83054.1 - 2.3 8.2 34.3 0.2 11.7 11.9 4.3 4 0 0 4 4 4 0 Mucin-like glycoprotein Gal-bind_lectin PF00337.22 CDJ83055.1 - 3.1e-05 23.5 0.0 4.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Galactoside-binding lectin MFS_1 PF07690.16 CDJ83056.1 - 9.2e-30 103.7 39.7 6.6e-24 84.5 29.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C4 PF00105.18 CDJ83057.1 - 7.2e-26 90.4 15.9 1.4e-25 89.5 15.9 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ83057.1 - 1.4e-25 90.1 0.0 2.1e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor RVT_1 PF00078.27 CDJ83060.1 - 0.0024 17.4 0.0 0.0033 17.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CLP1_N PF16573.5 CDJ83060.1 - 0.11 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 N-terminal beta-sandwich domain of polyadenylation factor Gmad2 PF10648.9 CDJ83060.1 - 0.11 12.7 0.0 17 5.7 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin-like domain of bacterial spore germination DUF3629 PF12302.8 CDJ83061.1 - 0.014 14.8 0.1 0.022 14.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) ABC2_membrane_3 PF12698.7 CDJ83064.1 - 5.9e-29 101.3 17.3 1e-28 100.5 17.3 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 CDJ83064.1 - 5.3e-20 72.3 0.0 8.9e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CDJ83064.1 - 2e-10 41.0 0.0 2.8e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CDJ83064.1 - 0.12 12.9 0.7 0.21 12.1 0.7 1.3 1 0 0 1 1 1 0 AAA domain NMT1 PF09084.11 CDJ83065.1 - 0.1 12.6 0.1 0.14 12.1 0.1 1.1 1 0 0 1 1 1 0 NMT1/THI5 like ECH_1 PF00378.20 CDJ83067.1 - 1.6e-32 112.8 0.4 1.9e-32 112.6 0.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CDJ83067.1 - 2.5e-08 33.8 0.1 4e-08 33.1 0.1 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase HMG_box_2 PF09011.10 CDJ83071.1 - 0.0057 17.2 2.1 0.015 15.9 2.1 1.8 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 CDJ83071.1 - 0.15 12.5 3.1 0.13 12.7 1.1 2.0 2 0 0 2 2 2 0 HMG (high mobility group) box Myb_DNA-bind_7 PF15963.5 CDJ83072.1 - 5.9e-06 26.1 0.2 2.1e-05 24.3 0.2 1.9 1 0 0 1 1 1 1 Myb DNA-binding like Cas_GSU0053 PF09617.10 CDJ83072.1 - 0.0073 16.3 0.5 0.013 15.4 0.5 1.4 1 0 0 1 1 1 1 CRISPR-associated protein GSU0053 (Cas_GSU0053) Bap31_Bap29_C PF18035.1 CDJ83072.1 - 0.23 11.5 2.6 6.7 6.8 0.3 2.6 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain A_deamin PF02137.18 CDJ83073.1 - 8.6e-87 291.6 0.0 1.1e-86 291.3 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.26 CDJ83073.1 - 0.008 16.9 0.0 0.015 16.0 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Daxx PF03344.15 CDJ83073.1 - 0.16 12.0 0.1 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Daxx N-terminal Rassf1C-interacting domain Fer4 PF00037.27 CDJ83074.1 - 1.4e-14 53.2 17.3 5.2e-09 35.6 4.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 CDJ83074.1 - 7.9e-14 52.0 9.8 1.2e-13 51.4 9.8 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 CDJ83074.1 - 2e-11 44.6 4.8 1.3e-05 26.0 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 CDJ83074.1 - 4.8e-10 39.4 32.6 4.1e-06 26.8 13.1 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 CDJ83074.1 - 2.1e-09 37.3 22.0 8.4e-07 29.0 12.7 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 CDJ83074.1 - 6.4e-09 35.8 10.0 1e-08 35.2 10.0 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CDJ83074.1 - 6.6e-08 32.9 19.6 2.1e-05 24.9 11.1 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 CDJ83074.1 - 2e-07 30.8 17.7 0.00035 20.5 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 CDJ83074.1 - 8e-07 28.8 11.9 0.0017 18.3 1.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 CDJ83074.1 - 4.6e-06 26.7 10.7 0.00031 21.0 2.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 CDJ83074.1 - 7.1e-05 23.3 11.2 0.0024 18.4 12.1 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 CDJ83074.1 - 0.0049 17.1 4.7 0.57 10.4 0.5 2.3 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_13 PF13370.6 CDJ83074.1 - 0.0056 17.2 14.9 0.24 12.0 2.9 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 CDJ83074.1 - 0.0075 17.1 16.5 0.013 16.4 4.2 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_18 PF13746.6 CDJ83074.1 - 0.056 13.6 9.3 3 8.1 1.6 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 CDJ83074.1 - 0.32 11.1 6.0 1.3 9.2 0.7 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 CDJ83074.1 - 0.62 10.9 11.4 1.7 9.5 1.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.27 CDJ83075.1 - 1.5e-14 53.1 17.3 5.3e-09 35.5 4.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 CDJ83075.1 - 1.9e-13 50.8 10.0 3.1e-13 50.1 10.0 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 CDJ83075.1 - 3.6e-11 43.8 5.8 8.1e-06 26.7 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 CDJ83075.1 - 7e-10 38.9 20.8 9.6e-07 28.8 12.4 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 CDJ83075.1 - 8e-10 38.7 32.9 3e-06 27.3 12.7 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 CDJ83075.1 - 2.5e-09 37.1 7.7 4.6e-09 36.3 7.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CDJ83075.1 - 1.8e-07 31.5 19.4 6e-05 23.4 11.2 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 CDJ83075.1 - 2.1e-07 30.7 17.7 0.00036 20.5 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 CDJ83075.1 - 1e-06 28.5 12.1 0.0021 18.1 1.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 CDJ83075.1 - 4.1e-06 26.9 10.4 0.00027 21.2 1.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 CDJ83075.1 - 0.00011 22.7 11.5 0.0094 16.5 12.5 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 CDJ83075.1 - 0.0049 17.4 14.9 0.24 12.0 2.9 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 CDJ83075.1 - 0.008 17.1 16.5 0.014 16.3 4.2 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.10 CDJ83075.1 - 0.0088 16.2 5.0 0.56 10.5 0.4 2.3 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 CDJ83075.1 - 0.067 13.4 9.5 7 6.9 9.6 2.3 1 1 0 1 1 1 0 4Fe-4S dicluster domain ETF_QO PF05187.13 CDJ83075.1 - 0.22 11.7 5.7 1.4 9.0 0.6 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 CDJ83075.1 - 0.5 11.2 11.5 2 9.3 1.6 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain EPF PF17181.4 CDJ83075.1 - 0.53 10.3 4.8 0.5 10.4 0.6 2.2 2 0 0 2 2 2 0 Epidermal patterning factor proteins Fer4 PF00037.27 CDJ83076.1 - 4.2e-14 51.7 16.4 1.4e-08 34.2 3.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 CDJ83076.1 - 2.1e-12 47.4 9.5 3.5e-12 46.7 9.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 CDJ83076.1 - 3.6e-11 43.8 4.9 1.9e-05 25.5 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 CDJ83076.1 - 5.6e-10 39.2 32.6 1.9e-06 27.9 12.5 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 CDJ83076.1 - 8.1e-09 35.5 9.3 1.6e-08 34.6 9.3 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 CDJ83076.1 - 9.4e-08 32.1 22.1 4.1e-05 23.6 13.5 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 CDJ83076.1 - 4.2e-07 29.8 18.4 0.00043 20.2 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 CDJ83076.1 - 6.2e-07 29.8 19.8 2.5e-05 24.6 10.4 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 CDJ83076.1 - 9.4e-07 28.6 12.0 0.0017 18.4 1.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 CDJ83076.1 - 9.6e-06 25.7 11.9 0.00055 20.2 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 CDJ83076.1 - 0.00059 20.3 12.3 0.028 15.0 13.1 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 CDJ83076.1 - 0.0033 17.9 14.1 0.15 12.7 2.2 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 CDJ83076.1 - 0.011 16.6 16.5 0.016 16.1 4.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.10 CDJ83076.1 - 0.023 14.9 5.0 0.84 9.9 0.5 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 CDJ83076.1 - 0.062 13.5 8.9 3.9 7.7 1.6 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 CDJ83076.1 - 0.67 10.8 11.0 1.8 9.5 1.0 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 CDJ83076.1 - 1.6 8.9 6.4 1.6 8.9 0.6 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S EPF PF17181.4 CDJ83076.1 - 1.9 8.5 6.9 1.3 9.0 1.6 2.2 2 0 0 2 2 2 0 Epidermal patterning factor proteins DnaJ PF00226.31 CDJ83078.1 - 1.8e-23 82.4 0.9 1.8e-23 82.4 0.9 2.9 3 0 0 3 3 3 1 DnaJ domain TrbH PF07283.11 CDJ83078.1 - 0.0031 17.7 0.1 0.0056 16.9 0.1 1.4 1 0 0 1 1 1 1 Conjugal transfer protein TrbH Talin_middle PF09141.10 CDJ83078.1 - 0.0051 16.8 1.3 0.28 11.2 0.2 2.2 2 0 0 2 2 2 2 Talin, middle domain ALMT PF11744.8 CDJ83078.1 - 0.074 11.9 0.8 0.1 11.4 0.3 1.2 1 1 0 1 1 1 0 Aluminium activated malate transporter CTNNBL PF08216.11 CDJ83080.1 - 3e-33 114.1 0.5 3e-33 114.1 0.5 2.4 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Pkinase PF00069.25 CDJ83081.1 - 1.6e-40 139.2 0.1 2.5e-40 138.5 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ83081.1 - 6.9e-25 87.8 0.3 9.3e-25 87.4 0.3 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 CDJ83081.1 - 2e-10 40.9 0.0 3.9e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain Kdo PF06293.14 CDJ83081.1 - 0.0094 15.3 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDJ83081.1 - 0.041 13.2 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 CDJ83081.1 - 0.077 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Yop-YscD_cpl PF16697.5 CDJ83081.1 - 0.08 13.3 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Kunitz_legume PF00197.18 CDJ83081.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Trypsin and protease inhibitor Ofd1_CTDD PF10637.9 CDJ83082.1 - 0.049 13.0 0.1 0.069 12.5 0.1 1.2 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Asp PF00026.23 CDJ83084.1 - 1.3e-73 248.2 3.7 1.7e-73 247.8 3.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ83084.1 - 7e-12 45.9 3.6 3.4e-10 40.4 3.6 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CDJ83084.1 - 0.0013 19.3 0.1 1.6 9.4 0.0 3.1 3 0 0 3 3 3 2 Aspartyl protease CCDC106 PF15794.5 CDJ83086.1 - 0.23 11.2 2.8 0.26 11.0 2.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SRP-alpha_N PF04086.13 CDJ83086.1 - 0.29 11.0 7.9 0.36 10.7 7.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal AP3D1 PF06375.11 CDJ83086.1 - 0.67 10.2 5.7 0.8 9.9 5.7 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 SRP-alpha_N PF04086.13 CDJ83087.1 - 0.11 12.4 6.8 0.13 12.1 6.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CCDC106 PF15794.5 CDJ83087.1 - 0.24 11.1 2.9 0.29 10.8 2.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 AP3D1 PF06375.11 CDJ83087.1 - 0.63 10.3 5.5 0.79 9.9 5.5 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Shisa PF13908.6 CDJ83088.1 - 0.0084 16.4 0.0 0.01 16.1 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator CrgA PF06781.12 CDJ83088.1 - 0.083 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Cell division protein CrgA CCDC106 PF15794.5 CDJ83088.1 - 0.26 11.0 3.3 0.31 10.7 3.3 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 AP3D1 PF06375.11 CDJ83088.1 - 3.9 7.7 8.5 4.8 7.4 8.5 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Hexokinase_1 PF00349.21 CDJ83089.1 - 1.6e-69 233.8 0.0 2.1e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 CDJ83089.1 - 1.8e-46 158.5 0.0 3.1e-46 157.7 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 CDJ83090.1 - 1.5e-81 273.4 0.0 2e-81 273.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CDJ83090.1 - 6e-72 241.7 0.0 8.6e-72 241.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase RNA_pol_Rpb2_6 PF00562.28 CDJ83091.1 - 9.9e-97 324.4 0.0 2.6e-96 323.1 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CDJ83091.1 - 2.3e-32 112.2 0.0 3.5e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 CDJ83091.1 - 2.2e-28 98.2 0.1 5.2e-28 97.0 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 CDJ83091.1 - 2.6e-20 72.6 0.0 7.7e-20 71.1 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.12 CDJ83091.1 - 3.6e-13 49.3 0.0 9.6e-13 47.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 CDJ83091.1 - 5.3e-07 29.5 0.0 2.5e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 Integrase_H2C2 PF17921.1 CDJ83092.1 - 1.1e-15 57.4 0.1 4e-15 55.7 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 CDJ83092.1 - 1.1e-09 38.5 0.0 2.3e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CDJ83092.1 - 0.00082 19.5 0.0 0.002 18.3 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger LZ_Tnp_IS481 PF13011.6 CDJ83092.1 - 0.14 12.7 0.0 0.32 11.6 0.0 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 AAA_30 PF13604.6 CDJ83093.1 - 0.00025 20.8 0.1 0.00041 20.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CDJ83093.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase ResIII PF04851.15 CDJ83093.1 - 0.022 14.8 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 CDJ83093.1 - 0.024 14.5 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cep57_MT_bd PF06657.13 CDJ83094.1 - 1.4 9.4 5.3 14 6.2 0.3 3.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF4140 PF13600.6 CDJ83094.1 - 5.8 7.4 6.9 1.9 9.0 2.0 2.7 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) FYVE_2 PF02318.16 CDJ83095.1 - 8.8e-11 42.1 14.5 2.5e-08 34.1 10.5 2.4 1 1 1 2 2 2 2 FYVE-type zinc finger DZR PF12773.7 CDJ83095.1 - 2.8 8.0 13.1 46 4.1 2.2 2.3 1 1 1 2 2 2 0 Double zinc ribbon zf-piccolo PF05715.13 CDJ83095.1 - 3.3 7.9 16.6 43 4.3 16.7 2.3 1 1 1 2 2 2 0 Piccolo Zn-finger NRBF2 PF08961.10 CDJ83096.1 - 0.00012 21.7 1.3 0.00018 21.2 1.3 1.2 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator bZIP_1 PF00170.21 CDJ83096.1 - 0.0003 20.8 5.4 0.0005 20.1 5.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor ZapB PF06005.12 CDJ83096.1 - 0.0038 17.6 3.2 0.0061 17.0 3.2 1.3 1 0 0 1 1 1 1 Cell division protein ZapB DivIC PF04977.15 CDJ83096.1 - 0.0046 16.7 4.4 0.0081 15.9 4.4 1.3 1 0 0 1 1 1 1 Septum formation initiator Csm1_N PF18504.1 CDJ83096.1 - 0.0078 16.5 2.3 0.013 15.8 2.3 1.3 1 0 0 1 1 1 1 Csm1 N-terminal domain YabA PF06156.13 CDJ83096.1 - 0.0086 16.7 1.3 0.014 16.0 1.3 1.3 1 0 0 1 1 1 1 Initiation control protein YabA JIP_LZII PF16471.5 CDJ83096.1 - 0.024 14.8 1.4 0.044 14.0 1.0 1.6 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF5017 PF16409.5 CDJ83096.1 - 0.031 13.7 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5017) Uso1_p115_C PF04871.13 CDJ83096.1 - 0.04 14.3 1.2 0.06 13.7 1.2 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region LCD1 PF09798.9 CDJ83096.1 - 0.076 11.5 1.2 0.1 11.1 1.2 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein bZIP_2 PF07716.15 CDJ83096.1 - 0.17 12.0 9.7 0.14 12.3 6.4 2.0 1 1 1 2 2 2 0 Basic region leucine zipper GIT_CC PF16559.5 CDJ83096.1 - 0.37 10.7 1.5 0.71 9.8 1.5 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor APC_u14 PF16635.5 CDJ83096.1 - 1.4 9.5 7.0 0.81 10.3 4.0 2.0 1 1 1 2 2 2 0 Unstructured region on APC between SAMP and APC_crr MutL_C PF08676.11 CDJ83098.1 - 2.9e-26 92.0 0.2 1.2e-25 90.0 0.0 2.0 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 CDJ83098.1 - 3.4e-24 84.8 0.0 7.3e-24 83.7 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CDJ83098.1 - 5.4e-13 48.9 0.0 1.5e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDJ83098.1 - 8.4e-05 23.0 0.0 0.0002 21.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Tex_N PF09371.10 CDJ83099.1 - 6.7e-09 35.7 2.3 0.00073 19.2 0.0 2.5 1 1 1 2 2 2 2 Tex-like protein N-terminal domain GSHPx PF00255.19 CDJ83099.1 - 0.014 14.9 0.2 0.3 10.7 0.0 2.6 3 0 0 3 3 3 0 Glutathione peroxidase HAP2-GCS1 PF10699.9 CDJ83099.1 - 0.14 12.1 0.3 11 6.1 0.0 2.5 2 0 0 2 2 2 0 Male gamete fusion factor SET PF00856.28 CDJ83100.1 - 1.3e-28 100.5 0.1 2.9e-28 99.4 0.1 1.6 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.16 CDJ83100.1 - 1.2e-16 61.3 8.6 1.2e-16 61.3 8.6 2.4 2 0 0 2 2 2 1 Pre-SET motif MBD PF01429.19 CDJ83100.1 - 3e-08 33.2 0.0 8e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 Methyl-CpG binding domain TUDOR_5 PF18359.1 CDJ83100.1 - 1.5e-07 31.0 0.0 3.4e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 Dehydrin PF00257.19 CDJ83100.1 - 0.0021 18.6 4.1 0.0037 17.8 4.1 1.3 1 0 0 1 1 1 1 Dehydrin SR-25 PF10500.9 CDJ83100.1 - 0.0038 16.9 9.3 0.0076 15.9 9.3 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein XRCC4 PF06632.12 CDJ83100.1 - 0.17 10.7 4.6 0.26 10.1 4.6 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Nop53 PF07767.11 CDJ83100.1 - 0.43 9.9 10.3 0.71 9.2 10.3 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CCDC106 PF15794.5 CDJ83100.1 - 0.55 9.9 7.3 0.92 9.2 7.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 BUD22 PF09073.10 CDJ83100.1 - 0.84 8.9 14.1 1.3 8.3 14.1 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 CDJ83100.1 - 1.1 7.4 10.6 1.7 6.9 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4614 PF15391.6 CDJ83100.1 - 1.5 8.8 6.0 3.9 7.4 4.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) RNA_polI_A34 PF08208.11 CDJ83100.1 - 4.4 7.4 11.8 7 6.7 11.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DNA_topoisoIV PF00521.20 CDJ83101.1 - 1.4e-99 333.9 0.0 2.3e-99 333.2 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CDJ83101.1 - 6.3e-38 129.9 2.7 1.3e-37 128.9 2.7 1.6 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CDJ83101.1 - 1.8e-18 66.6 0.0 3.8e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CDJ83101.1 - 5.6e-13 49.4 0.0 1.3e-12 48.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CDJ83101.1 - 6.1e-07 29.6 0.0 2e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 Toprim domain zf-C2H2_4 PF13894.6 CDJ83102.1 - 0.013 16.2 1.7 0.013 16.2 1.7 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 CDJ83102.1 - 0.032 14.1 0.2 0.082 12.8 0.2 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 CDJ83102.1 - 0.054 13.8 1.7 0.19 12.1 1.7 2.0 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 CDJ83102.1 - 0.077 13.3 3.1 0.099 12.9 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon zf-C2H2_6 PF13912.6 CDJ83102.1 - 0.13 12.3 0.1 0.13 12.3 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf_UBZ PF18439.1 CDJ83102.1 - 0.27 10.9 5.2 0.12 12.0 2.1 2.0 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf_C2H2_ZHX PF18387.1 CDJ83102.1 - 3.7 7.3 5.4 6.4 6.5 0.6 2.7 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain DNA_topoisoIV PF00521.20 CDJ83103.1 - 1.7e-05 24.0 0.5 1.9e-05 23.8 0.5 1.0 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A BBIP10 PF14777.6 CDJ83103.1 - 0.048 13.2 0.4 0.5 10.0 0.1 2.2 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 LIM PF00412.22 CDJ83104.1 - 2.4e-60 200.6 45.6 6e-17 61.6 4.7 4.4 4 0 0 4 4 4 4 LIM domain RRM_1 PF00076.22 CDJ83104.1 - 1.1e-11 44.4 0.0 1.9e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ83104.1 - 0.0028 17.2 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 CDJ83106.1 - 9.9e-71 238.2 0.1 1.2e-70 237.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ83106.1 - 8.5e-37 126.8 0.0 1.1e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ83106.1 - 1.3e-05 24.6 0.0 6.5e-05 22.4 0.0 1.9 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 CDJ83106.1 - 0.0012 18.6 0.0 0.11 12.2 0.0 2.4 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_C PF00433.24 CDJ83106.1 - 0.002 18.8 0.0 0.004 17.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.14 CDJ83106.1 - 0.0084 15.5 2.1 0.0084 15.5 0.1 2.0 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Metallophos PF00149.28 CDJ83107.1 - 3.7e-31 109.2 0.1 5.3e-31 108.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glycos_transf_2 PF00535.26 CDJ83108.1 - 4.8e-32 111.1 0.0 7.6e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CDJ83108.1 - 4.9e-18 65.6 0.0 8.5e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_2 PF10111.9 CDJ83108.1 - 4.7e-05 23.0 0.0 0.00013 21.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 CDJ83108.1 - 0.00014 21.5 0.1 0.00032 20.3 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Aquarius_N PF16399.5 CDJ83109.1 - 5.8e-287 954.0 11.5 7.9e-287 953.6 11.5 1.2 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 CDJ83109.1 - 1.1e-28 100.2 0.0 3.6e-28 98.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CDJ83109.1 - 6.2e-27 95.0 0.5 6.1e-26 91.8 0.0 2.7 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.6 CDJ83109.1 - 1.4e-08 35.2 0.0 5.3e-08 33.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ83109.1 - 1.7e-06 27.9 0.0 0.0022 17.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 CDJ83109.1 - 4.4e-05 23.1 0.7 0.0056 16.3 0.0 2.9 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 CDJ83109.1 - 8.6e-05 22.6 0.0 0.00022 21.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ83109.1 - 0.00029 20.7 0.0 0.00063 19.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ATP_sub_h PF10775.9 CDJ83109.1 - 0.0018 18.2 0.2 0.0042 17.1 0.2 1.5 1 0 0 1 1 1 1 ATP synthase complex subunit h DnaB_C PF03796.15 CDJ83109.1 - 0.0084 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain PhoH PF02562.16 CDJ83109.1 - 0.0093 15.4 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.9 CDJ83109.1 - 0.0099 15.1 1.4 0.021 14.1 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 CDJ83109.1 - 0.026 14.8 0.0 0.11 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain RecA PF00154.21 CDJ83109.1 - 0.036 13.5 0.0 0.077 12.4 0.0 1.5 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA PF00004.29 CDJ83109.1 - 0.039 14.4 0.0 0.094 13.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 CDJ83109.1 - 0.039 13.8 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_25 PF13481.6 CDJ83109.1 - 0.044 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CDJ83109.1 - 0.047 14.1 0.0 0.19 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain Pantoate_transf PF02548.15 CDJ83109.1 - 0.089 12.2 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase Homeodomain PF00046.29 CDJ83110.1 - 5e-15 55.1 5.9 8.5e-15 54.4 5.9 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ83110.1 - 0.039 13.8 0.1 0.1 12.5 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain DUF4395 PF14340.6 CDJ83110.1 - 0.24 11.7 0.0 0.35 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4395) Pex14_N PF04695.13 CDJ83110.1 - 3.4 8.3 9.3 8.6 7.0 9.3 1.6 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region tRNA-synt_1b PF00579.25 CDJ83111.1 - 1.8e-21 76.8 0.0 5.4e-13 48.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Cu-oxidase_3 PF07732.15 CDJ83113.1 - 7.5e-33 113.1 6.2 7.7e-31 106.6 0.2 3.8 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 CDJ83113.1 - 1.3e-27 96.2 10.4 5.8e-23 81.2 3.6 4.7 4 1 0 4 4 4 3 Multicopper oxidase Cu-oxidase PF00394.22 CDJ83113.1 - 1.1e-19 71.2 0.0 2.7e-19 69.8 0.0 1.8 1 0 0 1 1 1 1 Multicopper oxidase Sec20 PF03908.13 CDJ83114.1 - 0.027 14.4 1.8 1.5 8.8 0.0 2.6 2 1 1 3 3 3 0 Sec20 Complex1_LYR_2 PF13233.6 CDJ83114.1 - 0.073 13.8 2.7 0.17 12.6 2.7 1.7 1 1 0 1 1 1 0 Complex1_LYR-like CNDH2_C PF16858.5 CDJ83115.1 - 7e-45 154.2 4.5 7e-45 154.2 4.5 2.0 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 CDJ83115.1 - 5e-24 84.7 1.3 1.8e-23 82.9 0.1 2.2 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Cnd2 PF05786.14 CDJ83115.1 - 0.00027 19.7 11.0 0.0028 16.4 0.3 2.1 2 0 0 2 2 2 2 Condensin complex subunit 2 PBP1_TM PF14812.6 CDJ83115.1 - 0.65 10.4 17.6 11 6.4 9.9 4.0 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal OAD_gamma PF04277.13 CDJ83115.1 - 0.92 10.1 2.1 16 6.2 0.1 2.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DNA_pol3_delta2 PF13177.6 CDJ83116.1 - 2.4e-09 37.2 0.3 5.8e-09 35.9 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.15 CDJ83116.1 - 3.6e-06 27.0 0.0 6.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 CDJ83116.1 - 1.6e-05 25.4 0.0 2.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ83116.1 - 0.00027 21.4 0.1 0.0012 19.3 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain Rep_fac_C PF08542.11 CDJ83116.1 - 0.0037 17.6 0.3 0.061 13.7 0.1 2.8 3 0 0 3 3 3 1 Replication factor C C-terminal domain DNA_pol3_delta PF06144.13 CDJ83116.1 - 0.0073 16.1 0.2 0.018 14.8 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit ABC_tran PF00005.27 CDJ83116.1 - 0.014 15.9 0.0 0.071 13.6 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 CDJ83116.1 - 0.038 14.1 0.0 0.096 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CDJ83116.1 - 0.069 13.4 0.3 0.29 11.4 0.2 2.1 2 1 0 2 2 2 0 AAA domain zf-C2H2 PF00096.26 CDJ83117.1 - 6.1e-23 79.9 67.3 0.0011 19.3 3.6 8.7 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ83117.1 - 1e-17 63.3 72.2 0.0027 18.4 1.1 9.0 9 0 0 9 9 9 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDJ83117.1 - 1.1e-11 44.6 22.0 7.9e-07 29.2 0.7 8.9 10 0 0 10 10 8 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 CDJ83117.1 - 0.017 15.1 63.5 0.036 14.1 2.3 8.5 9 1 0 9 9 9 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 CDJ83117.1 - 0.024 14.5 1.2 0.024 14.5 1.2 5.9 6 0 0 6 6 6 0 zinc-finger of a C2HC-type zf-met PF12874.7 CDJ83117.1 - 0.047 14.1 1.4 0.047 14.1 1.4 7.6 8 0 0 8 8 7 0 Zinc-finger of C2H2 type DUF2256 PF10013.9 CDJ83117.1 - 0.33 11.1 25.5 1.2 9.3 0.1 7.3 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_jaz PF12171.8 CDJ83117.1 - 1.1 9.6 49.3 1.2 9.6 0.1 9.3 10 0 0 10 10 10 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 CDJ83117.1 - 1.8 9.3 31.0 0.13 13.0 2.8 5.8 4 2 2 6 6 6 0 zinc-ribbon family NRIP1_repr_3 PF15689.5 CDJ83117.1 - 4.1 7.8 6.8 1 9.7 2.7 2.2 2 0 0 2 2 2 0 Nuclear receptor-interacting protein 1 repression 3 Zn-ribbon_8 PF09723.10 CDJ83117.1 - 9.6 6.4 37.7 0.19 11.9 0.7 6.8 4 1 3 7 7 7 0 Zinc ribbon domain Glyco_hydro_30 PF02055.16 CDJ83118.1 - 6.4e-59 199.7 0.0 7e-59 199.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain RgpF PF05045.12 CDJ83118.1 - 0.047 12.5 0.1 0.058 12.2 0.1 1.2 1 0 0 1 1 1 0 Rhamnan synthesis protein F bZIP_2 PF07716.15 CDJ83119.1 - 3.7e-05 23.7 12.3 3.7e-05 23.7 12.3 2.0 1 1 1 2 2 2 1 Basic region leucine zipper Sedlin_N PF04628.13 CDJ83120.1 - 2.1e-46 157.3 0.1 2.4e-46 157.1 0.1 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 CDJ83120.1 - 4.6e-08 33.1 0.2 9.2e-08 32.1 0.1 1.5 1 1 1 2 2 2 1 Sybindin-like family EFF-AFF PF14884.6 CDJ83121.1 - 3.1e-100 336.1 1.3 5.2e-100 335.3 1.3 1.3 1 0 0 1 1 1 1 Type I membrane glycoproteins cell-cell fusogen DEAD PF00270.29 CDJ83122.1 - 1.5e-37 129.1 0.1 2.8e-37 128.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ83122.1 - 2.1e-27 95.7 0.2 3.8e-25 88.4 0.0 2.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ83122.1 - 1.5e-07 31.6 0.0 3.1e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CDJ83122.1 - 0.00045 19.6 0.0 0.0009 18.6 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit EFF-AFF PF14884.6 CDJ83124.1 - 1.8e-146 488.8 8.0 2.1e-86 290.4 0.3 3.0 1 1 2 3 3 3 3 Type I membrane glycoproteins cell-cell fusogen Abhydro_lipase PF04083.16 CDJ83125.1 - 3.1e-25 87.5 0.1 1.4e-24 85.5 0.1 2.0 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 CDJ83125.1 - 1.7e-15 57.4 0.8 4.9e-15 55.9 0.8 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ83125.1 - 0.002 17.5 0.0 0.028 13.7 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDJ83125.1 - 0.045 14.4 0.0 0.083 13.5 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Ribosomal_S20p PF01649.18 CDJ83127.1 - 0.17 12.5 0.0 0.33 11.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S20 zf-C3HC4_2 PF13923.6 CDJ83128.1 - 7.1e-09 35.4 11.8 7.1e-09 35.4 11.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ83128.1 - 1.4e-08 34.9 12.6 1.4e-08 34.9 12.6 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CDJ83128.1 - 4.4e-08 32.9 13.2 4.4e-08 32.9 13.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ83128.1 - 1.6e-07 31.1 9.9 1.6e-07 31.1 9.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ83128.1 - 3.2e-07 30.3 8.7 3.2e-07 30.3 8.7 1.8 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDJ83128.1 - 2e-06 27.8 10.7 2e-06 27.8 10.7 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 CDJ83128.1 - 2.2e-06 27.4 1.6 3.5e-06 26.8 1.6 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 CDJ83128.1 - 7.1e-06 25.9 10.9 1.6e-05 24.8 10.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDJ83128.1 - 0.0017 18.1 10.8 0.0038 17.1 10.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 CDJ83128.1 - 0.0045 16.8 7.0 0.0045 16.8 7.0 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 CDJ83128.1 - 0.0046 16.7 7.1 0.013 15.3 7.1 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zinc_ribbon_9 PF14369.6 CDJ83128.1 - 0.0056 16.9 2.3 0.02 15.1 2.3 2.1 1 0 0 1 1 1 1 zinc-ribbon Baculo_IE-1 PF05290.11 CDJ83128.1 - 0.011 15.7 2.4 0.016 15.1 2.4 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.7 CDJ83128.1 - 0.036 14.4 14.9 0.038 14.3 12.4 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger domain DZR PF12773.7 CDJ83128.1 - 0.08 13.0 6.4 3.8 7.6 7.7 2.3 1 1 1 2 2 2 0 Double zinc ribbon zf-ANAPC11 PF12861.7 CDJ83128.1 - 0.11 12.5 3.7 0.27 11.3 3.7 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UDP PF14569.6 CDJ83128.1 - 0.18 11.9 2.6 0.42 10.8 2.6 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_11 PF17123.5 CDJ83128.1 - 2.2 8.1 10.2 1 9.2 7.2 2.0 1 1 1 2 2 2 0 RING-like zinc finger IBR PF01485.21 CDJ83128.1 - 9.5 6.5 13.8 11 6.3 7.0 3.0 2 1 1 3 3 2 0 IBR domain, a half RING-finger domain SMC_N PF02463.19 CDJ83129.1 - 1.6e-14 53.9 4.8 1.8e-13 50.4 4.9 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CDJ83129.1 - 2.7e-11 44.3 14.5 2.7e-11 44.3 14.5 4.9 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.6 CDJ83129.1 - 0.03 14.0 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 CDJ83129.1 - 0.19 11.5 6.5 0.95 9.2 0.2 3.4 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 CDJ83129.1 - 0.58 10.7 0.0 0.58 10.7 0.0 4.7 3 2 1 4 4 4 0 ABC transporter SNARE PF05739.19 CDJ83129.1 - 0.88 9.6 10.0 1.6 8.8 0.2 3.6 4 0 0 4 4 4 0 SNARE domain QVR PF17064.5 CDJ83130.1 - 0.00097 19.3 3.7 0.0023 18.1 1.5 2.1 2 0 0 2 2 2 1 Sleepless protein Ly-6_related PF06579.12 CDJ83130.1 - 0.17 12.1 7.4 0.36 11.1 1.4 2.2 1 1 1 2 2 2 0 Caenorhabditis elegans ly-6-related protein HbrB PF08539.11 CDJ83131.1 - 0.0002 21.4 3.8 0.0049 16.9 0.1 2.4 1 1 1 2 2 2 2 HbrB-like NTF2 PF02136.20 CDJ83132.1 - 0.0016 19.0 0.0 0.0017 18.9 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4468 PF14730.6 CDJ83132.1 - 0.038 14.3 0.0 0.038 14.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4468) with TBP-like fold Sec34 PF04136.15 CDJ83133.1 - 1.3e-37 129.0 1.9 1.6e-37 128.7 0.4 2.0 2 0 0 2 2 2 1 Sec34-like family FAM92 PF06730.11 CDJ83133.1 - 0.023 14.1 0.3 0.051 13.0 0.3 1.5 1 0 0 1 1 1 0 FAM92 protein Neur_chan_LBD PF02931.23 CDJ83134.1 - 4.8e-55 186.3 2.9 4.4e-53 179.9 2.9 2.2 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ83134.1 - 6.2e-47 160.7 0.4 8.1e-47 160.3 0.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2417 PF10329.9 CDJ83134.1 - 0.25 10.8 4.4 0.067 12.6 1.0 1.7 2 0 0 2 2 2 0 Region of unknown function (DUF2417) 7TM_GPCR_Sra PF02117.16 CDJ83135.1 - 0.21 10.4 0.0 0.26 10.1 0.0 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sra ANAPC4_WD40 PF12894.7 CDJ83137.1 - 0.00012 22.4 0.6 19 5.6 0.1 5.0 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ83137.1 - 0.094 13.6 0.3 31 5.6 0.0 4.1 4 1 0 4 4 4 0 WD domain, G-beta repeat Ribosomal_S13_N PF08069.12 CDJ83138.1 - 3.7e-31 107.0 0.4 8.2e-31 105.8 0.4 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 CDJ83138.1 - 6.1e-13 48.8 0.8 9.8e-13 48.1 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 CDJ83138.1 - 0.0024 17.8 0.1 0.0058 16.5 0.1 1.7 2 1 0 2 2 2 1 'Paired box' domain R3H PF01424.22 CDJ83139.1 - 6.1e-11 42.1 0.0 1.5e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 CDJ83139.1 - 6.4e-10 38.9 67.0 5.9e-05 23.0 15.0 13.9 15 2 0 15 15 15 7 NF-X1 type zinc finger Ldl_recept_a PF00057.18 CDJ83140.1 - 1.6e-11 44.2 6.4 1.4e-10 41.2 6.4 2.8 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A zf-C2H2 PF00096.26 CDJ83142.1 - 2.9e-06 27.4 21.6 0.012 16.1 4.7 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ83142.1 - 7.6e-05 23.2 25.5 0.02 15.7 0.7 4.1 4 0 0 4 4 3 3 C2H2-type zinc finger zf-met PF12874.7 CDJ83142.1 - 0.0019 18.5 17.2 0.091 13.2 0.6 3.7 3 0 0 3 3 3 3 Zinc-finger of C2H2 type APG6_N PF17675.1 CDJ83142.1 - 0.0024 18.4 0.3 0.0073 16.8 0.3 1.7 1 0 0 1 1 1 1 Apg6 coiled-coil region Tho2 PF11262.8 CDJ83142.1 - 0.02 14.1 0.2 0.032 13.4 0.2 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4472 PF14739.6 CDJ83142.1 - 0.053 14.2 1.1 0.15 12.8 1.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) DUF4824 PF16106.5 CDJ83142.1 - 0.1 11.8 1.4 0.18 11.1 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4824) zf-C2H2_jaz PF12171.8 CDJ83142.1 - 0.15 12.4 0.1 0.15 12.4 0.1 3.6 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CDJ83142.1 - 0.23 11.8 13.7 0.073 13.4 4.6 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 CDJ83142.1 - 0.79 9.8 7.6 9.2 6.4 0.5 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CDJ83142.1 - 2 8.8 14.9 4.1e+02 1.4 1.2 3.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) ERM PF00769.19 CDJ83142.1 - 7.5 6.3 10.2 0.93 9.3 5.7 1.7 2 0 0 2 2 2 0 Ezrin/radixin/moesin family BTB_2 PF02214.22 CDJ83143.1 - 2.2e-19 69.6 0.0 4.2e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 CDJ83143.1 - 0.021 15.0 0.0 0.06 13.6 0.0 1.7 2 0 0 2 2 2 0 BTB/POZ domain BTB_3 PF16017.5 CDJ83143.1 - 0.054 13.6 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain BTB_2 PF02214.22 CDJ83144.1 - 3e-19 69.1 0.1 4.7e-19 68.5 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 CDJ83144.1 - 0.0022 18.1 0.0 0.0041 17.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 CDJ83144.1 - 0.018 15.3 0.0 0.029 14.6 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Abhydro_lipase PF04083.16 CDJ83145.1 - 3.6e-22 77.7 0.1 6.4e-22 76.9 0.1 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 CDJ83145.1 - 9e-16 58.3 0.2 4.4e-14 52.7 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ83145.1 - 9.8e-07 29.6 0.1 1.3e-06 29.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDJ83145.1 - 0.00018 20.9 0.0 0.0025 17.1 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF4302 PF14135.6 CDJ83145.1 - 0.14 12.1 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4302) DUF900 PF05990.12 CDJ83145.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Jnk-SapK_ap_N PF09744.9 CDJ83146.1 - 1.6e-30 106.4 12.3 1.6e-30 106.4 12.3 3.4 1 1 3 4 4 4 1 JNK_SAPK-associated protein-1 RILP PF11461.8 CDJ83146.1 - 7.9e-11 42.0 7.2 7.9e-11 42.0 7.2 3.0 3 1 1 4 4 1 1 Rab interacting lysosomal protein YabA PF06156.13 CDJ83146.1 - 0.03 15.0 7.5 0.03 15.0 7.5 4.1 1 1 3 4 4 4 0 Initiation control protein YabA DUF2935 PF11155.8 CDJ83146.1 - 0.035 14.4 1.1 0.035 14.4 1.1 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF2935) LMBR1 PF04791.16 CDJ83146.1 - 0.055 12.4 11.8 0.074 11.9 11.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Mod_r PF07200.13 CDJ83146.1 - 0.07 13.2 37.2 0.045 13.9 12.2 3.5 2 1 2 4 4 4 0 Modifier of rudimentary (Mod(r)) protein DUF1759 PF03564.15 CDJ83146.1 - 0.56 10.1 15.5 0.24 11.3 0.9 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1759) Baculo_PEP_C PF04513.12 CDJ83146.1 - 0.61 10.1 11.2 3.8 7.6 0.4 2.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.8 CDJ83146.1 - 0.93 9.6 34.6 2.4 8.3 14.5 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Prefoldin PF02996.17 CDJ83146.1 - 0.97 9.4 23.2 0.41 10.6 0.5 4.8 4 1 0 4 4 4 0 Prefoldin subunit PRKG1_interact PF15898.5 CDJ83146.1 - 1.1 10.2 35.6 0.7 10.8 6.0 3.4 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain GIT_CC PF16559.5 CDJ83146.1 - 1.3 8.9 33.2 0.2 11.6 1.2 5.2 3 2 3 6 6 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF948 PF06103.11 CDJ83146.1 - 1.5 9.2 12.4 3.8 7.8 1.7 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) WD40_alt PF14077.6 CDJ83146.1 - 1.6 8.7 6.5 0.32 10.9 1.5 2.5 2 1 0 2 2 2 0 Alternative WD40 repeat motif APG6_N PF17675.1 CDJ83146.1 - 1.7 9.2 47.1 7.2 7.1 15.3 3.5 1 1 2 3 3 3 0 Apg6 coiled-coil region HisKA_3 PF07730.13 CDJ83146.1 - 2.1 8.9 9.2 0.64 10.6 0.8 3.5 2 2 0 2 2 2 0 Histidine kinase FAM184 PF15665.5 CDJ83146.1 - 2.5 7.8 37.5 0.1 12.3 11.7 3.1 1 1 1 3 3 3 0 Family with sequence similarity 184, A and B FUSC PF04632.12 CDJ83146.1 - 2.8 6.4 9.2 2.8 6.4 4.0 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family TPR_MLP1_2 PF07926.12 CDJ83146.1 - 2.9 8.0 41.0 0.3 11.1 12.3 3.9 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein TACC_C PF05010.14 CDJ83146.1 - 3.4 7.4 36.4 8.6 6.1 5.5 3.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Sec20 PF03908.13 CDJ83146.1 - 4.8 7.2 13.8 0.57 10.1 1.0 3.3 2 1 1 3 3 3 0 Sec20 GAS PF13851.6 CDJ83146.1 - 6.7 6.0 42.2 0.24 10.7 14.8 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding MbeD_MobD PF04899.12 CDJ83146.1 - 6.9 6.9 13.4 3.6 7.8 0.4 4.3 3 2 1 4 4 4 0 MbeD/MobD like Lectin_N PF03954.14 CDJ83146.1 - 7.2 6.4 15.8 0.14 11.9 2.9 3.2 2 1 2 4 4 3 0 Hepatic lectin, N-terminal domain DUF1664 PF07889.12 CDJ83146.1 - 7.9 6.5 19.6 0.92 9.6 1.1 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF2115 PF09888.9 CDJ83146.1 - 8.3 6.9 11.6 14 6.2 0.4 3.2 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) HAUS-augmin3 PF14932.6 CDJ83146.1 - 8.6 5.8 38.0 0.15 11.6 12.2 3.1 1 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 KapB PF08810.10 CDJ83146.1 - 8.9 6.5 8.1 1.1 9.5 1.6 2.4 2 0 0 2 2 2 0 Kinase associated protein B Cmc1 PF08583.10 CDJ83147.1 - 1e-08 35.1 2.9 1e-08 35.1 2.9 1.5 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 CDJ83147.1 - 0.0081 16.3 0.3 0.015 15.4 0.3 1.5 1 0 0 1 1 1 1 CHCH domain Ribosomal_L24e PF01246.20 CDJ83148.1 - 1.6e-31 108.3 2.9 1.6e-31 108.3 2.9 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e zf-C3HC4_5 PF17121.5 CDJ83148.1 - 0.12 12.3 1.0 0.21 11.5 1.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2175 PF09943.9 CDJ83148.1 - 1.6 9.1 5.3 0.59 10.5 0.4 2.3 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Glyco_hydro_38N PF01074.22 CDJ83149.1 - 2.3e-88 296.3 3.6 3.5e-88 295.7 3.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 CDJ83149.1 - 5.6e-29 101.7 0.2 1.9e-28 100.0 0.0 2.0 3 0 0 3 3 3 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 CDJ83149.1 - 1.6e-23 82.7 1.5 3.2e-23 81.7 0.2 2.2 2 0 0 2 2 2 1 Alpha mannosidase middle domain MbeD_MobD PF04899.12 CDJ83149.1 - 0.06 13.5 2.8 1.3 9.2 0.1 2.8 2 0 0 2 2 2 0 MbeD/MobD like Fib_alpha PF08702.10 CDJ83149.1 - 0.35 11.0 2.8 0.35 11.1 0.5 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family R3H PF01424.22 CDJ83151.1 - 6.4e-10 38.9 0.0 1.6e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 R3H domain Peptidase_A17 PF05380.13 CDJ83152.1 - 3.5e-39 134.4 0.6 7.7e-39 133.3 0.6 1.6 1 0 0 1 1 1 1 Pao retrotransposon peptidase RVT_1 PF00078.27 CDJ83152.1 - 1e-16 61.2 0.0 5.5e-07 29.3 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1759 PF03564.15 CDJ83152.1 - 5.8e-14 52.3 0.9 2.1e-13 50.4 0.9 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 CDJ83152.1 - 1.9e-11 44.0 0.0 4.5e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 CDJ83152.1 - 0.00064 20.3 0.0 0.0022 18.6 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ83152.1 - 0.0037 17.8 0.1 0.022 15.3 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DpnD-PcfM PF14207.6 CDJ83152.1 - 6.1 6.8 6.6 11 6.0 0.5 3.6 3 0 0 3 3 3 0 DpnD/PcfM-like protein Wbp11 PF09429.10 CDJ83153.1 - 3.4e-05 24.2 16.8 0.00035 20.9 16.8 2.4 1 1 0 1 1 1 1 WW domain binding protein 11 MCD_N PF17408.2 CDJ83153.1 - 0.14 12.3 0.7 0.3 11.2 0.7 1.6 1 1 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain AAA_23 PF13476.6 CDJ83153.1 - 0.3 11.5 6.5 0.53 10.8 6.5 1.3 1 0 0 1 1 1 0 AAA domain DUF724 PF05266.14 CDJ83153.1 - 3 7.6 7.9 0.74 9.6 4.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF724) RFX_DNA_binding PF02257.15 CDJ83154.1 - 8.4e-33 112.9 0.1 2.2e-32 111.5 0.1 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain DUF3510 PF12022.8 CDJ83154.1 - 0.072 13.5 0.0 0.44 10.9 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3510) Pox_D5 PF03288.16 CDJ83154.1 - 0.11 13.0 0.5 0.39 11.2 0.0 2.1 3 0 0 3 3 3 0 Poxvirus D5 protein-like Lipase_GDSL PF00657.22 CDJ83155.1 - 0.011 15.7 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase IBR PF01485.21 CDJ83155.1 - 0.027 14.7 1.1 6.5 7.1 0.1 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain MAP17 PF15807.5 CDJ83155.1 - 0.037 14.2 0.0 0.055 13.7 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Clc-like PF07062.12 CDJ83158.1 - 5.8e-84 280.8 6.7 7.1e-84 280.5 6.7 1.1 1 0 0 1 1 1 1 Clc-like Claudin_2 PF13903.6 CDJ83158.1 - 6.8e-09 35.8 4.2 1.1e-08 35.1 4.2 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 CDJ83158.1 - 0.0007 19.5 10.5 0.027 14.3 0.1 2.2 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family DUF975 PF06161.11 CDJ83158.1 - 0.011 15.5 1.9 0.011 15.5 1.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF975) SUR7 PF06687.12 CDJ83158.1 - 0.057 13.0 16.5 0.8 9.3 17.5 2.2 1 1 1 2 2 2 0 SUR7/PalI family DuoxA PF10204.9 CDJ83158.1 - 0.96 8.4 9.5 0.18 10.8 6.0 1.5 2 0 0 2 2 2 0 Dual oxidase maturation factor Clc-like PF07062.12 CDJ83159.1 - 1.1e-29 103.4 8.7 1.1e-28 100.2 8.7 2.0 1 1 0 1 1 1 1 Clc-like Claudin_2 PF13903.6 CDJ83159.1 - 1.6e-06 28.0 6.6 1.1e-05 25.3 6.6 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Ldl_recept_a PF00057.18 CDJ83160.1 - 1.5e-18 66.7 25.0 1e-09 38.4 9.3 2.3 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A PSS PF03034.15 CDJ83162.1 - 2.2e-38 132.6 6.0 3.2e-38 132.1 6.0 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase PSS PF03034.15 CDJ83163.1 - 4.2e-47 161.2 7.4 5.7e-47 160.8 7.4 1.1 1 0 0 1 1 1 1 Phosphatidyl serine synthase Castor1_N PF18700.1 CDJ83164.1 - 0.032 14.1 0.5 2.8 7.9 0.0 2.2 1 1 1 2 2 2 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain ABC_tran PF00005.27 CDJ83167.1 - 6.5e-37 127.1 0.0 4.7e-18 66.0 0.0 2.7 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CDJ83167.1 - 1.5e-11 44.2 5.2 0.00078 18.9 0.1 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CDJ83167.1 - 1.3e-09 38.3 0.6 0.27 11.0 1.3 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 CDJ83167.1 - 1e-07 31.4 3.9 2e-07 30.5 3.9 1.4 1 0 0 1 1 1 1 4Fe-4S binding domain AAA_16 PF13191.6 CDJ83167.1 - 5.3e-07 30.2 0.0 0.013 15.9 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 CDJ83167.1 - 7.2e-06 26.4 0.1 0.062 13.7 0.1 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 CDJ83167.1 - 1.2e-05 25.3 0.1 0.076 12.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 CDJ83167.1 - 1.4e-05 25.4 0.0 0.0086 16.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_6 PF12837.7 CDJ83167.1 - 2.7e-05 24.0 2.8 5.1e-05 23.2 2.8 1.5 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4_7 PF12838.7 CDJ83167.1 - 4.2e-05 24.1 0.4 8.9e-05 23.0 0.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_29 PF13555.6 CDJ83167.1 - 9e-05 22.1 0.3 0.56 10.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 CDJ83167.1 - 0.00014 21.7 1.9 0.57 9.8 0.8 2.8 3 1 0 3 3 2 2 AAA ATPase domain SRP54 PF00448.22 CDJ83167.1 - 0.00021 21.0 0.9 0.097 12.3 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_23 PF13476.6 CDJ83167.1 - 0.00025 21.6 3.9 0.0064 17.0 0.1 2.5 2 1 0 2 2 2 1 AAA domain Fer4_9 PF13187.6 CDJ83167.1 - 0.00042 20.4 1.2 0.00095 19.3 1.2 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain TsaE PF02367.17 CDJ83167.1 - 0.00049 20.1 0.0 0.019 14.9 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CDJ83167.1 - 0.00052 20.0 0.1 0.34 10.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_7 PF12775.7 CDJ83167.1 - 0.00058 19.4 0.0 0.016 14.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 CDJ83167.1 - 0.00074 19.9 0.0 0.94 9.9 0.0 2.8 2 0 0 2 2 2 1 RNA helicase Fer4_16 PF13484.6 CDJ83167.1 - 0.0011 19.8 0.3 0.0029 18.5 0.3 1.7 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 CDJ83167.1 - 0.0012 18.9 4.8 0.0022 18.1 4.8 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 CDJ83167.1 - 0.0014 18.7 0.1 0.0026 17.8 0.1 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Rad17 PF03215.15 CDJ83167.1 - 0.0014 18.6 0.0 0.53 10.2 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain MMR_HSR1 PF01926.23 CDJ83167.1 - 0.0016 18.5 0.2 0.32 11.1 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 CDJ83167.1 - 0.002 18.3 0.2 0.75 9.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain Fer4_17 PF13534.6 CDJ83167.1 - 0.0033 17.9 0.2 0.0094 16.5 0.2 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_28 PF13521.6 CDJ83167.1 - 0.0047 17.2 0.0 1.8 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CDJ83167.1 - 0.0053 16.8 0.1 0.54 10.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 CDJ83167.1 - 0.0062 16.7 0.2 7.1 6.9 0.0 3.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 CDJ83167.1 - 0.0063 17.1 0.1 5.3 7.6 0.1 2.9 2 1 0 2 2 2 0 AAA domain Fer4_2 PF12797.7 CDJ83167.1 - 0.0072 16.4 1.8 0.014 15.4 1.8 1.5 1 0 0 1 1 1 1 4Fe-4S binding domain AAA_30 PF13604.6 CDJ83167.1 - 0.0088 15.8 0.3 0.94 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 CDJ83167.1 - 0.012 14.8 0.0 1.5 8.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 CDJ83167.1 - 0.014 15.1 1.9 1.4 8.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain Fer4_3 PF12798.7 CDJ83167.1 - 0.03 15.3 4.5 0.072 14.1 4.5 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain AAA_14 PF13173.6 CDJ83167.1 - 0.039 14.0 0.8 5.6 7.0 0.0 3.1 2 2 0 2 2 2 0 AAA domain Fer4_8 PF13183.6 CDJ83167.1 - 0.039 14.4 0.1 0.11 12.9 0.1 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain Thymidylate_kin PF02223.17 CDJ83167.1 - 0.056 13.1 0.0 13 5.4 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase TniB PF05621.11 CDJ83167.1 - 0.07 12.5 0.1 1.8 8.0 0.1 2.4 2 0 0 2 2 2 0 Bacterial TniB protein Fer4_22 PF17179.4 CDJ83167.1 - 0.074 13.9 2.0 0.22 12.4 2.0 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain VirE PF05272.11 CDJ83167.1 - 0.097 12.4 0.0 4.2 7.0 0.0 2.6 2 0 0 2 2 2 0 Virulence-associated protein E AAA_19 PF13245.6 CDJ83167.1 - 0.11 12.8 0.3 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_4 PF12800.7 CDJ83167.1 - 0.11 13.0 2.9 0.25 12.0 2.9 1.5 1 0 0 1 1 1 0 4Fe-4S binding domain Zeta_toxin PF06414.12 CDJ83167.1 - 0.12 11.7 0.1 2.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 CDJ83167.1 - 0.12 12.5 0.4 1 9.6 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 CDJ83167.1 - 0.2 11.6 3.2 9.4 6.1 0.0 3.4 3 0 0 3 3 3 0 NTPase AAA_13 PF13166.6 CDJ83167.1 - 0.31 9.6 0.0 0.31 9.6 0.0 2.0 3 0 0 3 3 2 0 AAA domain Pkinase PF00069.25 CDJ83168.1 - 3.2e-23 82.4 0.0 4.1e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ83168.1 - 1.9e-08 33.9 0.0 2.5e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ83168.1 - 0.043 13.2 0.1 0.071 12.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gp-FAR-1 PF05823.12 CDJ83169.1 - 2e-49 167.8 12.4 2.3e-49 167.6 12.4 1.0 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ApoLp-III PF07464.11 CDJ83169.1 - 2.3e-05 24.5 6.6 0.0097 16.0 0.5 2.3 1 1 1 2 2 2 2 Apolipophorin-III precursor (apoLp-III) Syntaxin PF00804.25 CDJ83169.1 - 0.0002 21.1 1.6 0.00027 20.7 1.6 1.1 1 0 0 1 1 1 1 Syntaxin Apolipoprotein PF01442.18 CDJ83169.1 - 0.00074 19.5 3.0 0.001 19.0 3.0 1.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain CdvA PF18822.1 CDJ83169.1 - 0.0089 15.9 6.2 0.29 10.9 0.7 3.0 2 1 1 3 3 3 1 CdvA-like coiled-coil domain DUF3106 PF11304.8 CDJ83169.1 - 0.022 15.2 1.4 1.4 9.5 1.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3106) TetR_C_3 PF08362.11 CDJ83169.1 - 0.023 14.6 0.5 0.042 13.8 0.5 1.6 1 1 0 1 1 1 0 YcdC-like protein, C-terminal region SieB PF14163.6 CDJ83169.1 - 0.041 13.4 0.6 2.2 7.8 0.0 2.3 1 1 0 2 2 2 0 Super-infection exclusion protein B DUF2063 PF09836.9 CDJ83169.1 - 0.098 12.9 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Putative DNA-binding domain GA PF01468.17 CDJ83169.1 - 0.17 12.2 4.4 0.76 10.1 1.2 2.9 3 0 0 3 3 3 0 GA module Cytochrom_C_2 PF01322.20 CDJ83169.1 - 1.8 9.5 9.1 2.3 9.1 6.1 2.3 1 1 1 2 2 2 0 Cytochrome C' ZapB PF06005.12 CDJ83169.1 - 1.9 9.0 7.8 3.8 8.0 1.4 2.7 2 2 0 2 2 2 0 Cell division protein ZapB YtxH PF12732.7 CDJ83169.1 - 3.5 8.2 13.1 7.7e+02 0.7 13.1 3.0 1 1 0 1 1 1 0 YtxH-like protein UQ_con PF00179.26 CDJ83170.1 - 5e-41 139.6 0.0 7.3e-41 139.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF1800 PF08811.11 CDJ83170.1 - 0.17 10.8 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Ras PF00071.22 CDJ83171.1 - 3.2e-63 212.2 0.4 3.9e-63 211.9 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ83171.1 - 3.6e-36 124.0 0.3 5.8e-36 123.3 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ83171.1 - 2.2e-13 50.1 0.0 2.5e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ83171.1 - 1.8e-05 24.8 0.0 2.4e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDJ83171.1 - 4.2e-05 23.0 0.0 5.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CDJ83171.1 - 0.00019 21.0 0.1 0.0004 20.0 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDJ83171.1 - 0.00034 20.6 0.7 0.32 10.9 0.0 2.2 2 1 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CDJ83171.1 - 0.0089 16.4 0.1 0.015 15.7 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain Tfb2_C PF18307.1 CDJ83171.1 - 0.092 13.2 0.2 3.1 8.3 0.1 2.3 2 0 0 2 2 2 0 Transcription factor Tfb2 (p52) C-terminal domain G-alpha PF00503.20 CDJ83171.1 - 0.1 11.7 0.0 0.14 11.3 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit CTP_transf_like PF01467.26 CDJ83172.1 - 2.1e-30 105.8 0.0 2.6e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like RPEL PF02755.15 CDJ83173.1 - 8.8e-14 50.7 7.2 2.6e-08 33.3 0.7 2.9 3 0 0 3 3 3 2 RPEL repeat PA26 PF04636.13 CDJ83174.1 - 2.2e-17 63.1 0.3 2.4e-17 63.0 0.3 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) CAMSAP_CKK PF08683.11 CDJ83174.1 - 0.035 14.2 0.0 0.035 14.2 0.0 1.0 1 0 0 1 1 1 0 Microtubule-binding calmodulin-regulated spectrin-associated Pkinase PF00069.25 CDJ83175.1 - 1.3e-25 90.3 0.0 1.7e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ83175.1 - 7.7e-14 51.6 0.0 1e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ83175.1 - 2.2e-06 26.7 0.3 3.3e-06 26.1 0.3 1.2 1 0 0 1 1 1 1 Fungal protein kinase PIP49_C PF12260.8 CDJ83175.1 - 0.003 17.2 0.0 0.0048 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 DUF2958 PF11171.8 CDJ83175.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2958) CK1gamma_C PF12605.8 CDJ83175.1 - 0.4 11.9 2.0 5.2 8.3 2.0 2.2 1 1 0 1 1 1 0 Casein kinase 1 gamma C terminal NICE-1 PF15845.5 CDJ83175.1 - 0.46 11.3 6.7 1.1 10.0 6.7 1.6 1 1 0 1 1 1 0 Cysteine-rich C-terminal 1 family DUF3361 PF11841.8 CDJ83176.1 - 1.5e-17 63.9 0.1 2.7e-17 63.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) UNC45-central PF11701.8 CDJ83176.1 - 5.1e-05 23.3 0.3 8.6e-05 22.5 0.3 1.3 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central Mic1 PF07035.12 CDJ83176.1 - 0.00049 19.8 0.5 0.00094 18.9 0.2 1.6 2 0 0 2 2 2 1 Colon cancer-associated protein Mic1-like Motile_Sperm PF00635.26 CDJ83177.1 - 2.6e-20 72.3 0.7 2.6e-20 72.3 0.7 1.8 2 0 0 2 2 2 1 MSP (Major sperm protein) domain PapD_N PF00345.20 CDJ83177.1 - 0.0078 16.1 0.0 0.019 14.9 0.0 1.7 1 1 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain 5-FTHF_cyc-lig PF01812.20 CDJ83178.1 - 2.4e-43 148.2 0.0 2.8e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family DUF735 PF05246.11 CDJ83178.1 - 0.21 11.5 0.0 0.3 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF735) BTB_2 PF02214.22 CDJ83179.1 - 1.5e-15 57.3 0.1 3.2e-15 56.3 0.1 1.5 1 1 0 1 1 1 1 BTB/POZ domain RVT_1 PF00078.27 CDJ83180.1 - 3.2e-15 56.2 0.0 4.9e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_9 PF12781.7 CDJ83180.1 - 0.027 13.6 1.7 0.14 11.2 1.7 2.0 1 1 0 1 1 1 0 ATP-binding dynein motor region BACK PF07707.15 CDJ83181.1 - 1e-05 25.6 0.0 2.9e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch Rgp1 PF08737.10 CDJ83181.1 - 4.4 6.4 15.4 1.3 8.1 10.5 2.1 2 0 0 2 2 2 0 Rgp1 Macoilin PF09726.9 CDJ83182.1 - 1.5 7.3 6.1 2 6.9 6.1 1.2 1 0 0 1 1 1 0 Macoilin family Bud13 PF09736.9 CDJ83182.1 - 3.3 8.1 13.2 0.45 10.9 8.2 1.8 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex RRM_1 PF00076.22 CDJ83183.1 - 6.9e-31 105.9 0.1 7.4e-15 54.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ83183.1 - 1.1e-08 35.0 0.1 0.0012 18.9 0.0 2.9 2 2 0 2 2 2 2 RNA recognition motif NID PF07292.13 CDJ83183.1 - 0.002 18.7 0.2 2.1 9.1 0.0 2.3 2 0 0 2 2 2 2 Nmi/IFP 35 domain (NID) CSD PF00313.22 CDJ83183.1 - 0.027 14.3 0.1 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain SCVP PF17619.2 CDJ83184.1 - 3.1e-17 63.2 0.7 3.9e-17 62.9 0.7 1.1 1 0 0 1 1 1 1 Secreted clade V proteins DUF4576 PF15144.6 CDJ83184.1 - 0.016 15.0 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) ZnuA PF01297.17 CDJ83184.1 - 0.083 12.3 0.1 0.09 12.2 0.1 1.1 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Ribosomal_L3 PF00297.22 CDJ83185.1 - 1.1e-177 590.5 9.7 1.3e-177 590.3 9.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 RRM_1 PF00076.22 CDJ83186.1 - 9.8e-31 105.4 0.0 2.9e-14 52.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_92 PF07971.12 CDJ83186.1 - 0.0039 16.2 0.0 0.007 15.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 92 Peptidase_C71 PF12386.8 CDJ83186.1 - 0.074 12.7 0.2 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei C2 PF00168.30 CDJ83188.1 - 8.8e-05 22.7 0.0 0.00014 22.1 0.0 1.3 1 0 0 1 1 1 1 C2 domain RVT_1 PF00078.27 CDJ83189.1 - 3.6e-16 59.4 0.0 3.9e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EF-hand_2 PF09068.11 CDJ83189.1 - 0.12 12.5 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 EF hand RdRP PF05183.12 CDJ83189.1 - 0.15 10.7 0.0 0.18 10.4 0.0 1.0 1 0 0 1 1 1 0 RNA dependent RNA polymerase RVT_1 PF00078.27 CDJ83190.1 - 4.7e-07 29.5 0.0 9e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1758 PF05585.12 CDJ83190.1 - 0.00035 20.4 0.0 0.00084 19.1 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) DUF1759 PF03564.15 CDJ83191.1 - 8.1e-19 68.0 1.5 3.9e-18 65.8 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1759) Kdo PF06293.14 CDJ83191.1 - 0.031 13.6 0.4 0.031 13.6 0.4 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SOGA PF11365.8 CDJ83191.1 - 0.047 14.8 1.6 3.2 8.9 0.0 3.0 2 2 1 3 3 3 0 Protein SOGA ALIX_LYPXL_bnd PF13949.6 CDJ83191.1 - 0.061 12.6 3.1 1.8 7.8 0.1 2.3 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV Gal_Lectin PF02140.18 CDJ83192.1 - 2.3e-29 101.6 5.3 1.1e-17 64.2 0.6 2.3 2 0 0 2 2 2 2 Galactose binding lectin domain FAM176 PF14851.6 CDJ83192.1 - 0.0017 18.0 0.2 0.0031 17.2 0.2 1.3 1 0 0 1 1 1 1 FAM176 family EphA2_TM PF14575.6 CDJ83192.1 - 0.049 14.5 0.1 14 6.7 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Yeast-kill-tox PF09207.11 CDJ83192.1 - 0.05 14.2 0.0 0.17 12.6 0.0 1.8 1 0 0 1 1 1 0 Yeast killer toxin TMEM154 PF15102.6 CDJ83192.1 - 0.11 12.4 0.5 0.24 11.3 0.5 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF3437 PF11919.8 CDJ83192.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) Peptidase_S8 PF00082.22 CDJ83194.1 - 5.7e-32 111.2 2.5 1.4e-31 109.8 2.5 1.6 1 1 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 CDJ83194.1 - 1.7e-20 72.8 0.1 3.3e-20 71.9 0.1 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 CDJ83194.1 - 7.4e-09 36.3 0.1 1.3e-08 35.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase S8 pro-domain OLF PF02191.16 CDJ83195.1 - 1.8e-57 194.8 4.7 2.2e-57 194.5 4.7 1.1 1 0 0 1 1 1 1 Olfactomedin-like domain Collagen PF01391.18 CDJ83195.1 - 9.5e-09 34.9 19.7 1.5e-08 34.3 19.7 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Collagen PF01391.18 CDJ83196.1 - 4.8e-22 77.5 83.4 9.5e-09 34.9 35.3 3.8 1 1 3 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ83196.1 - 3.4e-08 33.4 0.6 4.9e-08 32.9 0.6 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Neur_chan_LBD PF02931.23 CDJ83197.1 - 5.7e-70 235.1 2.6 8.4e-70 234.6 1.2 1.8 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ83197.1 - 6.9e-35 121.2 1.0 1.1e-34 120.6 1.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Glyco_transf_11 PF01531.16 CDJ83199.1 - 4.8e-08 32.6 0.1 6.8e-08 32.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 11 O-FucT PF10250.9 CDJ83199.1 - 0.00059 19.6 4.0 0.0049 16.6 4.0 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase TIP49 PF06068.13 CDJ83203.1 - 6.4e-161 535.4 0.0 8e-161 535.1 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CDJ83203.1 - 9.1e-15 54.6 0.1 2.7e-14 53.0 0.1 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 CDJ83203.1 - 2.7e-12 47.2 0.2 3.7e-08 33.9 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CDJ83203.1 - 1.4e-09 37.9 0.1 5e-06 26.4 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CDJ83203.1 - 5.7e-08 33.1 0.1 0.011 16.0 0.0 2.8 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 CDJ83203.1 - 1.7e-05 25.3 0.0 0.00034 21.1 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CDJ83203.1 - 1.9e-05 24.7 0.1 0.014 15.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 CDJ83203.1 - 0.00024 21.5 0.5 0.0031 17.9 0.5 2.4 1 1 0 1 1 1 1 AAA domain AAA_lid_2 PF17863.1 CDJ83203.1 - 0.00026 20.8 0.3 0.00062 19.6 0.3 1.6 1 0 0 1 1 1 1 AAA lid domain Sigma54_activat PF00158.26 CDJ83203.1 - 0.00054 19.7 0.1 1.4 8.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 CDJ83203.1 - 0.00068 19.1 0.1 0.037 13.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 CDJ83203.1 - 0.0017 18.0 0.0 0.0086 15.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CDJ83203.1 - 0.0061 17.1 0.0 0.031 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CDJ83203.1 - 0.0079 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 CDJ83203.1 - 0.0082 15.7 0.1 0.035 13.6 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region DnaB_C PF03796.15 CDJ83203.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain ResIII PF04851.15 CDJ83203.1 - 0.014 15.4 0.2 0.34 10.9 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.6 CDJ83203.1 - 0.014 15.5 0.0 6.9 6.8 0.0 2.8 2 1 1 3 3 3 0 Sigma-54 interaction domain AAA_28 PF13521.6 CDJ83203.1 - 0.025 14.8 0.0 0.053 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CDJ83203.1 - 0.026 14.6 0.0 9.2 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CDJ83203.1 - 0.035 14.0 0.0 0.23 11.4 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_11 PF13086.6 CDJ83203.1 - 0.039 13.7 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CDJ83203.1 - 0.045 13.0 0.1 0.1 11.9 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 CDJ83203.1 - 0.048 13.4 0.1 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CDJ83203.1 - 0.055 12.9 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.9 CDJ83203.1 - 0.062 12.5 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 CDJ83203.1 - 0.065 13.4 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CDJ83203.1 - 0.1 13.0 0.0 0.29 11.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 CDJ83203.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 CDJ83203.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Parvo_NS1 PF01057.17 CDJ83203.1 - 0.2 10.7 0.1 0.33 10.0 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 BORCS8 PF10167.9 CDJ83204.1 - 2.8e-30 104.5 0.0 3.7e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 MRP-S27 PF10037.9 CDJ83205.1 - 3.3e-83 279.7 0.1 4e-83 279.5 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 DUF2458 PF10454.9 CDJ83205.1 - 0.13 11.9 5.5 0.28 10.8 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) CENP-H PF05837.12 CDJ83205.1 - 0.66 10.4 7.4 1.7 9.1 7.4 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) zf-C2H2_4 PF13894.6 CDJ83206.1 - 1.2e-15 56.8 68.5 0.018 15.8 0.9 10.6 10 0 0 10 10 10 6 C2H2-type zinc finger zf-C2H2 PF00096.26 CDJ83206.1 - 1.8e-14 53.3 71.9 0.012 16.0 1.3 10.2 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ83206.1 - 5.5e-09 36.0 53.4 0.0012 19.1 4.6 9.3 9 0 0 9 9 9 4 Zinc-finger double domain zf-Di19 PF05605.12 CDJ83206.1 - 3.1e-06 27.4 38.4 0.0032 17.7 4.2 5.5 4 1 2 6 6 5 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 CDJ83206.1 - 0.00092 19.4 20.0 0.011 15.9 0.1 6.9 6 0 0 6 6 6 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 CDJ83206.1 - 0.0063 16.3 1.6 0.0063 16.3 1.6 7.8 8 0 0 8 8 8 2 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 CDJ83206.1 - 0.0095 16.2 3.5 0.0095 16.2 3.5 4.9 2 1 3 5 5 5 1 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 CDJ83206.1 - 0.21 11.9 34.0 0.029 14.7 3.2 6.2 3 1 3 6 6 6 0 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 CDJ83206.1 - 0.23 12.1 37.3 2 9.1 0.5 8.0 6 2 2 8 8 8 0 FOXP coiled-coil domain CpXC PF14353.6 CDJ83206.1 - 0.8 9.8 11.7 2 8.5 0.5 4.0 2 1 2 4 4 4 0 CpXC protein zinc_ribbon_9 PF14369.6 CDJ83206.1 - 4.2 7.7 20.1 11 6.3 0.3 5.8 6 0 0 6 6 6 0 zinc-ribbon zf-LYAR PF08790.11 CDJ83206.1 - 4.8 7.2 9.5 6.2 6.8 1.0 4.3 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-C2H2_9 PF16293.5 CDJ83206.1 - 5.5 6.9 24.7 2.1 8.2 0.1 7.5 8 1 1 9 9 9 0 C2H2 type zinc-finger (1 copy) ARS2 PF04959.13 CDJ83206.1 - 5.7 7.3 5.5 5.3 7.4 0.1 3.0 3 1 0 4 4 4 0 Arsenite-resistance protein 2 zf-ribbon_3 PF13248.6 CDJ83206.1 - 6 6.4 14.5 35 4.0 0.2 5.4 5 0 0 5 5 5 0 zinc-ribbon domain WD40 PF00400.32 CDJ83207.1 - 4.1e-24 84.4 24.0 1.1e-05 26.1 0.0 8.9 8 0 0 8 8 8 6 WD domain, G-beta repeat Bromodomain PF00439.25 CDJ83207.1 - 6.5e-21 74.2 0.0 4.3e-12 45.9 0.0 2.5 2 0 0 2 2 2 2 Bromodomain UQ_con PF00179.26 CDJ83207.1 - 1.2e-15 57.4 0.0 2.3e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ANAPC4_WD40 PF12894.7 CDJ83207.1 - 3.4e-07 30.5 0.7 2.8 8.3 0.0 5.1 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDJ83207.1 - 0.0032 16.2 0.8 0.052 12.2 0.1 2.4 2 1 0 2 2 2 1 Nucleoporin Nup120/160 WD40_like PF17005.5 CDJ83207.1 - 0.11 11.8 0.3 0.84 8.9 0.1 2.1 2 0 0 2 2 2 0 WD40-like domain ADH_zinc_N PF00107.26 CDJ83208.1 - 1.4e-21 76.8 0.2 2.4e-21 76.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDJ83208.1 - 1e-13 51.1 0.1 2.4e-13 49.9 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CDJ83208.1 - 1.6e-13 51.9 0.0 2.7e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.20 CDJ83208.1 - 0.00046 20.3 0.5 0.00077 19.6 0.5 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 CDJ83208.1 - 0.0092 15.5 0.1 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase AlaDh_PNT_C PF01262.21 CDJ83208.1 - 0.011 15.0 0.5 0.019 14.3 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 CDJ83208.1 - 0.054 13.2 0.1 0.083 12.6 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase LOB PF03195.14 CDJ83208.1 - 0.081 13.5 0.0 17 6.0 0.0 2.5 2 0 0 2 2 2 0 Lateral organ boundaries (LOB) domain Eno-Rase_NADH_b PF12242.8 CDJ83208.1 - 0.2 11.4 2.3 0.43 10.4 1.1 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RMI1_N PF08585.12 CDJ83209.1 - 3.9e-25 88.9 0.2 4.8e-17 62.5 0.2 2.5 1 1 0 2 2 2 2 RecQ mediated genome instability protein RMI1_C PF16099.5 CDJ83209.1 - 5e-08 32.9 0.2 1.4e-07 31.4 0.1 1.7 1 1 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold Mnd1 PF03962.15 CDJ83210.1 - 6.5e-28 96.8 0.4 1.6e-27 95.6 0.4 1.7 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 CDJ83210.1 - 2e-24 85.4 2.8 5.8e-24 83.9 2.8 1.8 1 0 0 1 1 1 1 Leucine zipper with capping helix domain Penicillinase_R PF03965.16 CDJ83210.1 - 0.018 15.4 0.1 0.032 14.6 0.1 1.5 1 1 0 1 1 1 0 Penicillinase repressor ATG16 PF08614.11 CDJ83210.1 - 0.019 15.2 9.7 0.019 15.2 9.7 2.4 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) HU-CCDC81_bac_2 PF18175.1 CDJ83210.1 - 0.033 14.1 0.1 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 FUR PF01475.19 CDJ83210.1 - 0.049 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Ferric uptake regulator family FapA PF03961.13 CDJ83210.1 - 0.084 11.5 4.6 0.094 11.3 4.6 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 CDJ83210.1 - 0.14 12.0 6.7 2.6 7.9 0.0 2.9 1 1 0 2 2 2 0 Septum formation initiator CSN5_C PF18323.1 CDJ83210.1 - 0.43 11.5 6.0 9 7.3 2.6 3.1 2 1 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain UPF0242 PF06785.11 CDJ83210.1 - 0.54 10.3 10.2 0.047 13.8 5.6 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 CDJ83210.1 - 1.2 8.1 10.1 0.3 10.1 6.6 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Swi5 PF07061.11 CDJ83210.1 - 6.5 6.9 9.0 1.5 8.9 4.3 2.4 2 1 1 3 3 3 0 Swi5 dsDNA_bind PF01984.20 CDJ83211.1 - 1.2e-24 86.8 8.8 1.4e-24 86.5 8.8 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain MPP6 PF10175.9 CDJ83211.1 - 0.022 15.2 2.7 0.028 14.9 2.7 1.1 1 0 0 1 1 1 0 M-phase phosphoprotein 6 PCI PF01399.27 CDJ83211.1 - 0.062 13.8 0.2 0.12 12.9 0.1 1.6 1 1 0 1 1 1 0 PCI domain RseA_C PF03873.13 CDJ83211.1 - 0.23 11.7 6.6 0.42 10.9 6.6 1.4 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain Copine PF07002.16 CDJ83213.1 - 1.8e-59 200.9 0.0 2.6e-59 200.3 0.0 1.2 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 CDJ83213.1 - 1.4e-06 28.6 0.0 2.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 CDJ83213.1 - 0.042 14.1 0.0 0.081 13.2 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain GPS PF01825.21 CDJ83214.1 - 0.0018 18.7 3.1 0.0018 18.7 3.1 2.3 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif Auxin_repressed PF05564.12 CDJ83214.1 - 0.11 13.2 0.1 0.33 11.6 0.1 1.8 1 0 0 1 1 1 0 Dormancy/auxin associated protein Antifungal_prot PF11402.8 CDJ83214.1 - 0.44 10.8 4.4 5.2 7.4 0.1 2.8 2 0 0 2 2 2 0 Antifungal protein Glyco_hydro_77 PF02446.17 CDJ83215.1 - 0.11 11.4 1.3 0.13 11.1 1.3 1.1 1 0 0 1 1 1 0 4-alpha-glucanotransferase YtxH PF12732.7 CDJ83215.1 - 0.2 12.2 3.3 0.42 11.2 3.3 1.5 1 0 0 1 1 1 0 YtxH-like protein DUF4085 PF13315.6 CDJ83215.1 - 0.23 11.1 2.7 5.1 6.7 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4085) DUF883 PF05957.13 CDJ83215.1 - 0.46 11.1 3.5 0.41 11.3 1.3 2.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) ATP-synt_B PF00430.18 CDJ83215.1 - 6.4 6.9 11.1 0.36 10.9 4.0 2.4 2 1 0 2 2 2 0 ATP synthase B/B' CF(0) PhaP_Bmeg PF09602.10 CDJ83215.1 - 8 6.4 9.7 0.09 12.7 1.7 1.8 3 0 0 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) ubiquitin PF00240.23 CDJ83217.1 - 3.8e-09 36.2 0.0 7.6e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family zf-AN1 PF01428.16 CDJ83217.1 - 5.8e-06 26.4 9.5 1.1e-05 25.5 9.5 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Ubiquitin_4 PF18036.1 CDJ83217.1 - 0.0056 16.7 0.1 3.6 7.7 0.0 3.0 2 1 1 3 3 3 2 Ubiquitin-like domain TBK1_ULD PF18396.1 CDJ83217.1 - 0.025 14.5 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD PF11976.8 CDJ83217.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Peptidase_S28 PF05577.12 CDJ83218.1 - 1.8e-148 494.9 3.7 5e-105 351.8 0.1 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 CDJ83218.1 - 8.3e-09 35.1 0.0 8.8e-06 25.2 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ83218.1 - 3.7e-07 30.0 0.2 2.1e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 CDJ83218.1 - 0.035 13.7 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 CDJ83218.1 - 0.043 13.3 0.0 0.092 12.2 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Globin PF00042.22 CDJ83219.1 - 0.091 13.3 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 Globin NHL PF01436.21 CDJ83220.1 - 0.00013 21.8 0.2 7.6 6.8 0.0 4.4 4 0 0 4 4 4 2 NHL repeat zf-B_box PF00643.24 CDJ83220.1 - 0.026 14.7 2.8 0.026 14.7 2.8 1.9 2 0 0 2 2 2 0 B-box zinc finger CheW PF01584.19 CDJ83220.1 - 0.16 11.6 0.0 0.4 10.3 0.0 1.7 1 0 0 1 1 1 0 CheW-like domain zf-piccolo PF05715.13 CDJ83220.1 - 2.8 8.2 5.8 0.47 10.6 1.6 2.0 2 0 0 2 2 2 0 Piccolo Zn-finger Neur_chan_LBD PF02931.23 CDJ83221.1 - 3.1e-45 154.3 0.3 4.7e-45 153.7 0.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ83221.1 - 1.6e-28 100.4 0.2 2.4e-26 93.3 0.0 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Lactamase_B_6 PF16661.5 CDJ83222.1 - 1.7e-54 184.2 0.3 7.8e-54 182.0 0.1 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 CDJ83222.1 - 1.5e-24 87.1 3.7 1.5e-22 80.6 0.0 3.3 2 1 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 CDJ83222.1 - 1.4e-20 73.6 0.0 3.9e-20 72.2 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 CDJ83222.1 - 2.2e-15 56.3 0.0 4.7e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 CDJ83222.1 - 1.7e-09 38.0 0.0 3.1e-08 33.9 0.0 2.4 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CDJ83222.1 - 1.3e-06 28.0 0.0 3.7e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 CDJ83222.1 - 0.00011 21.5 0.0 0.00029 20.1 0.0 1.6 1 1 0 1 1 1 1 Putative beta-lactamase-like family AA_kinase PF00696.28 CDJ83222.1 - 0.11 12.1 0.4 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 Amino acid kinase family Sorting_nexin PF03700.13 CDJ83222.1 - 0.13 12.8 2.5 0.29 11.7 2.5 1.5 1 0 0 1 1 1 0 Sorting nexin, N-terminal domain GST_N_4 PF17172.4 CDJ83223.1 - 1.7e-29 102.5 0.0 2.8e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 CDJ83223.1 - 1.5e-24 85.6 0.1 2.6e-24 84.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 CDJ83223.1 - 2e-10 41.1 0.0 3.2e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 CDJ83223.1 - 3.2e-06 27.1 0.0 5.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDJ83223.1 - 4.8e-05 23.7 0.0 0.00014 22.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CDJ83223.1 - 0.001 19.4 0.0 0.0019 18.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain FRB_dom PF08771.11 CDJ83223.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain zf-LITAF-like PF10601.9 CDJ83226.1 - 5.1e-12 45.9 12.8 6.6e-12 45.5 12.8 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Cys_rich_KTR PF14205.6 CDJ83226.1 - 0.028 14.2 0.1 0.028 14.2 0.1 2.0 2 0 0 2 2 2 0 Cysteine-rich KTR Rubella_Capsid PF05750.11 CDJ83226.1 - 0.08 12.5 3.5 0.088 12.4 3.5 1.2 1 0 0 1 1 1 0 Rubella capsid protein Ion_trans_2 PF07885.16 CDJ83227.1 - 1.4e-34 117.9 14.1 1.6e-18 66.4 1.1 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 CDJ83227.1 - 2.9e-08 33.3 6.8 0.00027 20.2 0.2 2.2 1 1 0 2 2 2 2 Ion transport protein Peptidase_M13 PF01431.21 CDJ83228.1 - 8.1e-76 254.2 0.3 1.6e-75 253.2 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13_N PF05649.13 CDJ83228.1 - 1.2e-13 51.6 0.4 2e-13 50.8 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M13 MvaI_BcnI PF15515.6 CDJ83228.1 - 0.005 16.7 0.2 0.0088 15.9 0.2 1.5 1 0 0 1 1 1 1 MvaI/BcnI restriction endonuclease family Peptidase_M13 PF01431.21 CDJ83229.1 - 8.6e-59 198.6 0.0 1.1e-58 198.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 ASC PF00858.24 CDJ83230.1 - 3.6e-13 49.3 2.4 4.8e-13 48.9 2.4 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Sugar_tr PF00083.24 CDJ83231.1 - 8.7e-121 403.9 30.3 1.1e-120 403.6 30.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ83231.1 - 1.2e-17 63.9 36.7 1.2e-17 63.9 36.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ83232.1 - 1.2e-95 321.1 27.6 1.9e-95 320.4 27.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ83232.1 - 1.9e-15 56.7 29.1 2.9e-15 56.1 29.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ83233.1 - 5.1e-113 378.3 28.5 5.1e-113 378.3 28.5 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ83233.1 - 1.1e-15 57.4 39.2 3.5e-15 55.8 35.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1942 PF09167.11 CDJ83233.1 - 0.081 12.9 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1942) Neur_chan_memb PF02932.16 CDJ83233.1 - 6.5 6.7 7.3 16 5.5 7.3 1.7 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3165 PF11364.8 CDJ83233.1 - 7.6 7.0 7.8 1.8 9.0 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3165) zf-U11-48K PF05253.12 CDJ83234.1 - 0.22 11.5 5.3 0.097 12.6 2.6 2.0 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger SCVP PF17619.2 CDJ83235.1 - 1e-23 84.0 0.2 1.2e-23 83.8 0.2 1.1 1 0 0 1 1 1 1 Secreted clade V proteins DUF2431 PF10354.9 CDJ83235.1 - 0.0035 17.6 0.1 0.0044 17.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Glyco_hydro_20b PF02838.15 CDJ83235.1 - 0.093 13.5 0.0 0.14 13.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 SPATA3 PF15662.5 CDJ83237.1 - 0.21 12.2 6.2 0.28 11.8 6.2 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family DDE_Tnp_IS1595 PF12762.7 CDJ83238.1 - 1.2e-16 61.1 0.0 1.5e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS66 PF03050.14 CDJ83238.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Transposase IS66 family Collagen PF01391.18 CDJ83239.1 - 7.5e-26 89.7 108.2 7.8e-10 38.4 36.6 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ83239.1 - 6.7e-19 67.7 0.2 8.4e-19 67.4 0.2 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain COX14 PF14880.6 CDJ83239.1 - 0.64 9.9 3.2 0.94 9.4 3.2 1.1 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Collagen PF01391.18 CDJ83240.1 - 2.3e-24 84.9 102.2 3.7e-10 39.4 29.9 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ83240.1 - 5.1e-09 36.1 0.2 6.5e-09 35.7 0.2 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ83241.1 - 1.5e-26 91.9 104.4 3.3e-11 42.8 33.9 4.0 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ83241.1 - 9.1e-13 48.1 0.1 1.2e-12 47.7 0.1 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain AMPK1_CBM PF16561.5 CDJ83242.1 - 2.7e-10 40.3 0.0 6.1e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase RGM_N PF06535.12 CDJ83242.1 - 0.019 15.2 0.2 0.039 14.1 0.2 1.5 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) N-terminus CBM_48 PF02922.18 CDJ83242.1 - 0.03 14.7 0.0 0.059 13.7 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Menin PF05053.13 CDJ83242.1 - 5 5.4 5.6 7.8 4.7 5.6 1.3 1 0 0 1 1 1 0 Menin Methyltransf_31 PF13847.6 CDJ83243.1 - 1.7e-19 70.1 0.2 7.1e-19 68.1 0.1 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ83243.1 - 3e-16 59.8 0.0 4.9e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ83243.1 - 3.1e-16 59.9 0.1 5.2e-16 59.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ83243.1 - 9.8e-13 48.7 0.0 1.6e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ83243.1 - 1.8e-12 47.4 0.0 2.7e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ83243.1 - 3.3e-06 26.6 1.1 3e-05 23.5 1.1 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 CDJ83243.1 - 0.00018 20.9 0.2 0.00038 19.8 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 CDJ83243.1 - 0.00023 20.7 0.0 0.00036 20.0 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 CDJ83243.1 - 0.00026 20.6 0.0 0.00039 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 CDJ83243.1 - 0.00033 19.9 0.0 0.00052 19.2 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase NodS PF05401.11 CDJ83243.1 - 0.00043 20.0 0.0 0.00058 19.5 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) PCMT PF01135.19 CDJ83243.1 - 0.00089 19.1 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 CDJ83243.1 - 0.00089 19.3 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CDJ83243.1 - 0.00093 18.7 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 CDJ83243.1 - 0.001 18.4 0.3 0.002 17.4 0.1 1.6 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_9 PF08003.11 CDJ83243.1 - 0.0023 16.9 0.0 0.0029 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 CDJ83243.1 - 0.0024 17.5 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Cons_hypoth95 PF03602.15 CDJ83243.1 - 0.0071 16.0 0.0 0.019 14.6 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 CDJ83243.1 - 0.021 14.8 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_PK PF05891.12 CDJ83243.1 - 0.064 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_8 PF05148.15 CDJ83243.1 - 0.077 12.8 0.2 1.1 9.0 0.1 2.4 2 1 0 2 2 2 0 Hypothetical methyltransferase DUF3052 PF11253.8 CDJ83243.1 - 0.13 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) Isochorismatase PF00857.20 CDJ83243.1 - 0.14 12.4 0.0 0.33 11.1 0.0 1.7 1 1 0 1 1 1 0 Isochorismatase family zf-C3HC4_3 PF13920.6 CDJ83244.1 - 3.7e-07 29.9 18.5 9.5e-07 28.6 18.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDJ83244.1 - 9.3e-05 22.2 14.4 0.00021 21.1 14.4 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF948 PF06103.11 CDJ83244.1 - 6.5 7.1 14.0 0.32 11.3 0.7 3.4 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) TRM PF02005.16 CDJ83245.1 - 3.6e-141 470.7 0.0 4.5e-141 470.4 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 CDJ83245.1 - 0.00011 22.0 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_15 PF09445.10 CDJ83245.1 - 0.029 13.9 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 CDJ83245.1 - 0.033 14.9 0.0 0.27 12.0 0.1 2.3 2 0 0 2 2 2 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 CDJ83245.1 - 0.037 13.0 0.1 0.086 11.8 0.0 1.5 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase Cons_hypoth95 PF03602.15 CDJ83245.1 - 0.039 13.6 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PrmA PF06325.13 CDJ83245.1 - 0.06 12.7 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 CDJ83245.1 - 0.15 12.0 0.0 0.46 10.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.32 CDJ83246.1 - 0.0021 18.8 0.0 0.27 12.2 0.0 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat TPR_14 PF13428.6 CDJ83246.1 - 0.0064 17.2 2.3 59 4.9 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ83246.1 - 0.039 14.3 0.3 4.2 8.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Lentiviral_Tat PF02998.14 CDJ83246.1 - 0.14 12.2 0.1 1.3 9.1 0.0 2.7 2 0 0 2 2 2 0 Lentiviral Tat protein Fis1_TPR_C PF14853.6 CDJ83246.1 - 0.19 11.8 3.6 2.2 8.4 0.2 3.6 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 CDJ83246.1 - 1.5 9.2 3.3 19 5.8 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ83246.1 - 1.8 8.5 9.5 49 4.0 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat CDC45 PF02724.14 CDJ83246.1 - 4.8 5.4 28.3 0.79 7.9 8.0 2.4 2 0 0 2 2 2 0 CDC45-like protein Col_cuticle_N PF01484.17 CDJ83247.1 - 0.00057 19.9 1.5 0.00074 19.5 1.5 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain BRCT PF00533.26 CDJ83248.1 - 1.1e-28 99.5 0.0 3.9e-09 36.8 0.0 4.5 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CDJ83248.1 - 2.9e-22 78.4 0.1 3.6e-14 52.5 0.0 3.9 4 0 0 4 4 4 3 twin BRCT domain BRCT_2 PF16589.5 CDJ83248.1 - 2.2e-13 50.4 0.0 0.00034 21.0 0.0 4.3 4 0 0 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 CDJ83248.1 - 1.1e-10 41.2 0.0 2.5e-07 30.5 0.0 2.4 2 0 0 2 2 2 2 Regulator of Ty1 transposition protein 107 BRCT domain C6 PF01681.17 CDJ83248.1 - 0.00057 20.3 0.3 0.001 19.5 0.3 1.5 1 0 0 1 1 1 1 C6 domain LIG3_BRCT PF16759.5 CDJ83248.1 - 0.00066 19.9 1.4 0.39 11.0 0.1 4.1 4 1 0 4 4 4 1 DNA ligase 3 BRCT domain C6 PF01681.17 CDJ83249.1 - 1.1e-05 25.9 0.1 1.1e-05 25.9 0.1 2.1 2 0 0 2 2 2 1 C6 domain ELO PF01151.18 CDJ83250.1 - 5.4e-50 170.2 22.8 6.2e-50 170.1 22.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family PH PF00169.29 CDJ83251.1 - 6.2e-19 68.5 0.5 6e-10 39.6 0.1 2.6 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 CDJ83251.1 - 2.6 8.5 10.5 7.2 7.1 0.1 4.5 4 1 0 4 4 4 0 Pleckstrin homology domain Glyco_hydro_38N PF01074.22 CDJ83252.1 - 1.7e-73 247.5 2.7 2.7e-73 246.8 2.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 CDJ83252.1 - 5.5e-22 77.7 0.3 1.2e-21 76.7 0.3 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_38C PF07748.13 CDJ83252.1 - 0.00015 21.9 0.0 0.00048 20.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain 7tm_1 PF00001.21 CDJ83253.1 - 2.9e-56 190.7 20.5 2.9e-56 190.7 20.5 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ83253.1 - 2e-10 40.5 29.5 3.8e-09 36.3 29.5 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 CDJ83253.1 - 3e-07 30.4 12.1 3e-07 30.4 12.1 2.2 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 CDJ83253.1 - 1.8e-06 27.9 15.1 1.8e-06 27.9 15.1 1.9 2 0 0 2 2 2 1 Olfactory receptor PP1c_bdg PF10488.9 CDJ83253.1 - 0.0016 18.0 0.2 1.3 8.4 0.2 2.3 2 0 0 2 2 2 2 Phosphatase-1 catalytic subunit binding region UCMA PF17085.5 CDJ83253.1 - 0.072 13.1 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Unique cartilage matrix associated protein SnoaL_3 PF13474.6 CDJ83254.1 - 4.9e-05 23.6 0.0 6.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 CDJ83254.1 - 6e-05 23.4 0.0 7.3e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF4783 PF16022.5 CDJ83254.1 - 0.0001 22.4 0.2 0.00025 21.2 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4783) DUF3225 PF11533.8 CDJ83254.1 - 0.012 15.3 0.0 0.013 15.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3225) LEDGF PF11467.8 CDJ83254.1 - 0.03 14.0 0.5 0.11 12.1 0.1 1.9 1 1 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) SnoaL_2 PF12680.7 CDJ83254.1 - 0.046 14.4 0.0 0.057 14.1 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain SnoaL_3 PF13474.6 CDJ83255.1 - 0.00077 19.7 0.0 0.0011 19.3 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 CDJ83255.1 - 0.0093 16.4 0.0 0.012 16.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 CDJ83255.1 - 0.016 15.8 0.0 0.019 15.6 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain LRR_6 PF13516.6 CDJ83256.1 - 9.1e-17 59.6 22.8 0.00016 21.5 0.0 9.1 10 0 0 10 10 10 4 Leucine Rich repeat LRR_4 PF12799.7 CDJ83256.1 - 9.7e-14 51.3 17.2 0.021 15.2 0.1 6.6 4 2 2 7 7 7 7 Leucine Rich repeats (2 copies) F-box-like PF12937.7 CDJ83256.1 - 2e-13 50.0 0.6 2e-13 50.0 0.6 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CDJ83256.1 - 5.2e-08 32.6 0.5 2.4e-07 30.4 0.5 2.2 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.33 CDJ83256.1 - 2.4e-06 27.3 31.7 0.63 10.8 0.1 11.1 10 2 0 10 10 10 2 Leucine Rich Repeat F-box_4 PF15966.5 CDJ83256.1 - 0.0058 16.5 2.5 0.24 11.3 0.0 2.6 2 1 0 2 2 2 1 F-box LRR_8 PF13855.6 CDJ83256.1 - 0.024 14.4 13.2 13 5.7 0.2 6.3 4 2 2 6 6 6 0 Leucine rich repeat DBC1 PF14443.6 CDJ83256.1 - 0.091 12.7 3.5 41 4.2 0.0 4.1 4 0 0 4 4 4 0 DBC1 Sad1_UNC PF07738.13 CDJ83257.1 - 2.1e-18 66.6 0.2 4.1e-18 65.7 0.2 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Apolipoprotein PF01442.18 CDJ83257.1 - 0.00091 19.2 7.7 0.0013 18.6 7.7 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain AAA_13 PF13166.6 CDJ83257.1 - 0.022 13.4 2.3 0.031 12.9 2.3 1.1 1 0 0 1 1 1 0 AAA domain GramPos_pilinD3 PF16570.5 CDJ83257.1 - 0.027 15.2 0.0 0.054 14.2 0.0 1.4 1 0 0 1 1 1 0 Gram-positive pilin backbone subunit 3, Cna-B-like domain Syntaxin-6_N PF09177.11 CDJ83257.1 - 0.031 14.8 1.5 0.067 13.8 1.5 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Lebercilin PF15619.6 CDJ83257.1 - 0.033 13.8 9.8 0.092 12.4 9.8 1.6 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Baculo_PEP_C PF04513.12 CDJ83257.1 - 0.21 11.6 1.5 1.3 9.0 1.5 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus LXG PF04740.12 CDJ83257.1 - 0.33 10.6 4.8 0.52 10.0 4.8 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily HisKA_3 PF07730.13 CDJ83257.1 - 0.35 11.4 6.0 0.65 10.6 0.9 2.5 2 0 0 2 2 2 0 Histidine kinase DUF3763 PF12592.8 CDJ83258.1 - 0.018 15.1 0.2 0.042 13.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3763) P22_AR_C PF10548.9 CDJ83258.1 - 0.14 12.3 0.0 0.53 10.5 0.0 2.0 1 1 1 2 2 2 0 P22AR C-terminal domain GST_N_3 PF13417.6 CDJ83259.1 - 6.8e-21 74.5 0.0 1.4e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CDJ83259.1 - 2e-16 60.1 0.1 3.4e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDJ83259.1 - 2e-14 53.6 0.0 3.9e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDJ83259.1 - 2.3e-05 24.3 0.0 4.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 CDJ83259.1 - 5.5e-05 23.3 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_N_4 PF17172.4 CDJ83259.1 - 0.078 13.7 0.0 0.14 12.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 CDJ83259.1 - 0.093 12.9 0.0 0.18 12.0 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Thioredoxin_3 PF13192.6 CDJ83259.1 - 0.21 11.7 0.0 0.36 10.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain TTR-52 PF01060.23 CDJ83260.1 - 7.9e-07 29.7 0.0 7.9e-07 29.7 0.0 3.3 4 0 0 4 4 4 1 Transthyretin-like family Peptidase_M35 PF02102.15 CDJ83260.1 - 0.55 9.0 8.3 0.8 8.5 0.6 2.5 1 1 2 3 3 3 0 Deuterolysin metalloprotease (M35) family DGF-1_C PF11040.8 CDJ83260.1 - 1.1 9.4 12.1 4.3 7.4 1.0 3.1 1 1 2 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus MobA_MobL PF03389.15 CDJ83260.1 - 7.9 6.1 11.7 8.5 6.0 0.6 3.3 2 1 2 4 4 4 0 MobA/MobL family TTR-52 PF01060.23 CDJ83261.1 - 1.3e-06 29.0 1.0 2.2e-06 28.3 0.0 2.0 2 1 0 2 2 2 1 Transthyretin-like family Mucin PF01456.17 CDJ83261.1 - 1.4 8.9 32.2 1.9 8.4 32.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 CDJ83261.1 - 7.5 4.6 25.7 9.1 4.3 25.7 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RVT_1 PF00078.27 CDJ83262.1 - 2.4e-19 69.8 0.0 1.7e-08 34.3 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2703 PF10865.8 CDJ83262.1 - 0.067 13.4 0.0 6.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) ANAPC10 PF03256.16 CDJ83263.1 - 2.2e-52 177.4 0.0 2.8e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) TPR_1 PF00515.28 CDJ83265.1 - 1.8e-42 141.4 19.7 5.7e-09 35.4 1.1 6.9 7 0 0 7 7 7 6 Tetratricopeptide repeat Gal-bind_lectin PF00337.22 CDJ83265.1 - 3.5e-33 114.0 0.0 5.1e-33 113.4 0.0 1.3 1 0 0 1 1 1 1 Galactoside-binding lectin TPR_2 PF07719.17 CDJ83265.1 - 5.4e-33 110.4 14.9 1.3e-08 34.3 0.7 6.8 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ83265.1 - 1.5e-26 91.7 7.7 1.7e-10 40.4 0.2 4.8 4 0 0 4 4 4 3 TPR repeat TPR_12 PF13424.6 CDJ83265.1 - 1.5e-19 70.0 7.5 9.7e-08 32.2 0.2 5.4 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ83265.1 - 6e-19 68.4 1.1 4.6e-06 27.2 0.0 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ83265.1 - 2.6e-18 65.1 2.9 0.0045 17.7 0.0 7.1 4 2 4 8 8 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ83265.1 - 5e-18 63.7 18.2 0.0009 19.3 0.2 6.8 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ83265.1 - 3e-15 56.5 1.1 0.0011 19.4 0.0 4.9 3 1 1 4 4 4 3 Tetratricopeptide repeat STI1 PF17830.1 CDJ83265.1 - 3.9e-15 55.5 0.6 6.1e-14 51.7 0.3 2.9 3 0 0 3 3 2 1 STI1 domain TPR_17 PF13431.6 CDJ83265.1 - 4e-13 48.7 11.8 0.00019 21.6 0.1 5.8 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ83265.1 - 1e-12 47.5 5.7 0.11 12.4 0.1 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ83265.1 - 2.5e-10 39.7 2.1 2.3 8.5 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ83265.1 - 2.4e-07 30.7 5.3 0.19 11.9 0.1 5.0 5 0 0 5 5 5 3 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 CDJ83265.1 - 1e-06 28.8 0.6 0.04 14.1 0.0 4.3 3 1 2 5 5 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ83265.1 - 3.1e-06 27.3 6.2 0.024 14.8 1.1 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 CDJ83265.1 - 0.00024 20.1 6.1 0.0021 17.1 6.1 2.1 1 1 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 CDJ83265.1 - 0.00029 21.3 5.5 5.3 7.9 0.0 5.7 7 0 0 7 7 4 1 Tetratricopeptide repeat BTAD PF03704.17 CDJ83265.1 - 0.0044 17.5 2.3 1.4 9.4 0.2 3.3 3 0 0 3 3 3 1 Bacterial transcriptional activator domain DnaI_N PF07319.11 CDJ83265.1 - 0.017 15.8 1.6 11 6.8 0.0 3.6 3 1 0 3 3 3 0 Primosomal protein DnaI N-terminus Sel1 PF08238.12 CDJ83265.1 - 0.025 15.2 2.0 26 5.7 0.1 4.2 3 0 0 3 3 3 0 Sel1 repeat Alkyl_sulf_dimr PF14863.6 CDJ83265.1 - 0.068 13.6 3.8 7.7 7.0 0.0 3.4 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation TPR_21 PF09976.9 CDJ83265.1 - 0.1 12.3 10.1 1.1 8.9 0.3 3.8 1 1 1 3 3 3 0 Tetratricopeptide repeat-like domain MIT PF04212.18 CDJ83265.1 - 0.45 10.6 14.2 11 6.2 0.6 5.2 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain CHAD PF05235.14 CDJ83265.1 - 0.82 9.6 6.7 4.7 7.1 6.7 2.0 1 1 0 1 1 1 0 CHAD domain PPR PF01535.20 CDJ83265.1 - 1.4 9.3 5.5 12 6.4 0.0 4.6 5 0 0 5 5 5 0 PPR repeat SMBP PF16785.5 CDJ83265.1 - 1.9 8.7 4.9 7.8 6.8 2.2 2.7 1 1 1 2 2 2 0 Small metal-binding protein TPR_20 PF14561.6 CDJ83265.1 - 2.4 8.5 6.4 5.7 7.3 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 CDJ83265.1 - 2.9 7.5 6.7 0.79 9.4 0.9 2.8 1 1 1 2 2 2 0 26S proteasome subunit RPN7 SRP_TPR_like PF17004.5 CDJ83265.1 - 6.9 6.7 8.2 2.5 8.1 2.1 2.9 2 1 1 3 3 3 0 Putative TPR-like repeat FERM_C PF09380.10 CDJ83266.1 - 4.4e-22 78.3 1.1 1e-21 77.1 1.1 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 CDJ83266.1 - 5.4e-16 59.1 0.1 2e-15 57.2 0.0 2.0 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.10 CDJ83266.1 - 8.6e-15 54.4 0.0 2.1e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain FA PF08736.11 CDJ83266.1 - 3.1e-13 49.6 4.2 1.5e-12 47.4 4.2 2.3 1 0 0 1 1 1 1 FERM adjacent (FA) PH PF00169.29 CDJ83266.1 - 1.5e-11 44.8 0.5 1.3e-08 35.3 0.3 3.1 2 0 0 2 2 2 2 PH domain RhoGEF PF00621.20 CDJ83266.1 - 0.002 18.4 0.4 0.0059 16.9 0.0 2.0 2 0 0 2 2 2 1 RhoGEF domain UNC45-central PF11701.8 CDJ83267.1 - 8.5e-24 84.3 0.1 5.9e-22 78.3 0.0 3.0 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central TPR_2 PF07719.17 CDJ83267.1 - 2.5e-08 33.4 16.9 0.0041 17.1 0.5 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ83267.1 - 2.4e-05 24.0 7.5 0.026 14.3 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ83267.1 - 0.0012 19.1 2.3 0.0012 19.1 2.3 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ83267.1 - 0.0041 17.7 4.7 0.0041 17.7 4.7 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ83267.1 - 0.014 15.6 5.2 0.023 14.8 1.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ83267.1 - 0.04 14.1 6.5 1 9.7 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ83267.1 - 1.3 8.8 4.9 3.6 7.3 0.4 3.1 3 0 0 3 3 3 0 TPR repeat Syndecan PF01034.20 CDJ83268.1 - 6.2e-28 96.5 0.1 1.2e-27 95.6 0.1 1.4 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.18 CDJ83268.1 - 0.00053 20.2 1.6 0.0012 19.1 0.1 2.2 1 1 1 2 2 2 1 Glycophorin A MGC-24 PF05283.11 CDJ83268.1 - 0.0019 18.6 4.7 0.0024 18.3 0.3 2.2 1 1 1 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin EphA2_TM PF14575.6 CDJ83268.1 - 0.1 13.5 0.2 2 9.4 0.0 2.5 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain FeoB_associated PF12669.7 CDJ83268.1 - 1.1 9.7 2.9 0.6 10.6 0.2 1.9 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein PDZ PF00595.24 CDJ83269.1 - 1.3e-07 31.9 0.0 2.2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDJ83269.1 - 0.00095 19.0 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain FANCI_S4 PF14678.6 CDJ83270.1 - 0.046 12.8 0.1 0.073 12.2 0.1 1.3 1 0 0 1 1 1 0 FANCI solenoid 4 RhodobacterPufX PF11511.8 CDJ83270.1 - 0.047 13.3 1.6 0.12 12.0 1.6 1.7 1 0 0 1 1 1 0 Intrinsic membrane protein PufX Peptidase_M48_N PF16491.5 CDJ83270.1 - 0.27 11.1 0.1 0.27 11.1 0.1 2.2 2 0 0 2 2 2 0 CAAX prenyl protease N-terminal, five membrane helices DUF2207 PF09972.9 CDJ83270.1 - 1.3 7.7 3.9 7.3 5.2 1.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF2207 PF09972.9 CDJ83271.1 - 0.016 14.0 2.8 0.089 11.5 0.6 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) RhodobacterPufX PF11511.8 CDJ83271.1 - 0.045 13.4 1.8 0.12 12.0 1.8 1.7 1 0 0 1 1 1 0 Intrinsic membrane protein PufX Glyco_transf_34 PF05637.12 CDJ83271.1 - 0.069 12.9 0.0 8.4 6.0 0.0 2.3 2 0 0 2 2 2 0 galactosyl transferase GMA12/MNN10 family DUF1189 PF06691.11 CDJ83271.1 - 0.099 12.2 4.1 0.2 11.2 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) FA_desaturase PF00487.24 CDJ83271.1 - 0.8 9.5 6.4 1.2 8.9 0.8 2.2 2 0 0 2 2 2 0 Fatty acid desaturase Ank_2 PF12796.7 CDJ83272.1 - 2e-60 201.4 22.1 3.7e-12 46.6 0.1 10.4 3 2 4 9 9 9 9 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ83272.1 - 3.4e-43 145.1 22.0 2.9e-08 33.8 0.1 13.8 6 4 7 14 14 14 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDJ83272.1 - 6e-43 144.7 22.3 0.0001 22.8 0.0 14.6 6 4 10 16 16 16 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ83272.1 - 3.3e-40 131.5 24.7 0.0017 18.6 0.0 17.4 21 0 0 21 21 21 9 Ankyrin repeat Ank PF00023.30 CDJ83272.1 - 1.8e-26 91.3 24.5 0.0087 16.5 0.0 14.5 16 0 0 16 16 16 7 Ankyrin repeat FYVE PF01363.21 CDJ83272.1 - 1e-14 54.4 8.4 2.5e-14 53.2 8.4 1.7 1 0 0 1 1 1 1 FYVE zinc finger BTB PF00651.31 CDJ83272.1 - 2.9e-08 33.9 0.2 8.5e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 CDJ83272.1 - 0.057 13.5 0.1 0.31 11.2 0.0 2.2 2 0 0 2 2 2 0 BTB And C-terminal Kelch Aldolase PF01081.19 CDJ83272.1 - 0.085 12.3 0.0 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 KDPG and KHG aldolase FYVE_2 PF02318.16 CDJ83272.1 - 5 7.4 8.7 1.4 9.2 5.2 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger p450 PF00067.22 CDJ83273.1 - 3e-90 303.2 0.2 3.4e-90 303.0 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fibrinogen_C PF00147.18 CDJ83274.1 - 4.1e-34 118.3 4.5 4.1e-34 118.3 4.5 1.5 2 0 0 2 2 2 1 Fibrinogen beta and gamma chains, C-terminal globular domain Lectin_C PF00059.21 CDJ83274.1 - 0.007 17.1 4.7 0.007 17.1 4.7 2.4 2 0 0 2 2 2 1 Lectin C-type domain Poxvirus_B22R PF04395.12 CDJ83274.1 - 0.45 10.0 7.6 0.71 9.4 7.6 1.2 1 0 0 1 1 1 0 Poxvirus B22R protein Fibrinogen_C PF00147.18 CDJ83275.1 - 9.3e-35 120.4 5.9 2.5e-34 119.0 5.9 1.7 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Lectin_C PF00059.21 CDJ83275.1 - 9.9e-14 52.0 10.5 9.9e-14 52.0 10.5 2.4 2 1 0 2 2 2 1 Lectin C-type domain p450 PF00067.22 CDJ83276.1 - 1.9e-94 317.0 0.0 2.2e-94 316.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SIL1 PF16782.5 CDJ83276.1 - 0.013 14.8 0.3 0.02 14.1 0.3 1.2 1 0 0 1 1 1 0 Nucleotide exchange factor SIL1 ketoacyl-synt PF00109.26 CDJ83277.1 - 3.6e-110 367.5 2.9 2.7e-52 177.9 0.0 3.5 3 0 0 3 3 3 3 Beta-ketoacyl synthase, N-terminal domain PP-binding PF00550.25 CDJ83277.1 - 1.6e-108 355.1 17.3 5.9e-12 45.8 0.1 9.8 9 0 0 9 9 9 9 Phosphopantetheine attachment site KR PF08659.10 CDJ83277.1 - 1.5e-95 318.2 0.6 5e-45 153.6 0.0 5.4 5 0 0 5 5 5 4 KR domain Ketoacyl-synt_C PF02801.22 CDJ83277.1 - 4.3e-88 291.2 0.4 2.3e-32 111.5 0.1 3.9 3 0 0 3 3 3 3 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 CDJ83277.1 - 1.2e-51 176.2 0.0 2.9e-31 109.2 0.0 2.6 2 0 0 2 2 2 2 Acyl transferase domain AMP-binding PF00501.28 CDJ83277.1 - 3.2e-44 151.2 0.0 2.5e-43 148.3 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 CDJ83277.1 - 1.4e-37 129.5 0.7 2.4e-37 128.7 0.7 1.2 1 0 0 1 1 1 1 Condensation domain KAsynt_C_assoc PF16197.5 CDJ83277.1 - 3.3e-33 114.5 0.0 3.5e-15 56.4 0.0 3.8 3 0 0 3 3 3 3 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 CDJ83277.1 - 5e-15 55.5 8.1 1.9e-06 27.5 0.6 4.8 4 1 0 4 4 4 2 short chain dehydrogenase Epimerase PF01370.21 CDJ83277.1 - 1e-13 51.4 0.1 6.7e-06 25.7 0.0 2.7 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 CDJ83277.1 - 8.8e-13 48.3 0.2 0.00052 19.6 0.0 3.8 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase PS-DH PF14765.6 CDJ83277.1 - 7.1e-10 38.6 0.0 2.1e-09 37.0 0.0 1.7 1 1 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.20 CDJ83277.1 - 7.4e-09 36.1 0.0 2.2e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 Thioesterase domain AMP-binding_C PF13193.6 CDJ83277.1 - 3.1e-07 31.3 0.1 9.1e-07 29.8 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 CDJ83277.1 - 0.00023 20.7 1.8 3.5 6.9 0.0 4.2 4 0 0 4 4 4 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CDJ83277.1 - 0.00037 19.6 4.8 0.028 13.5 0.4 3.1 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CDJ83277.1 - 0.0017 17.6 1.4 5 6.2 0.0 3.5 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 CDJ83277.1 - 0.0025 17.7 0.1 9.2 6.1 0.0 3.7 3 0 0 3 3 3 0 NAD(P)H-binding GCV_H PF01597.19 CDJ83277.1 - 0.0071 16.2 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage H-protein LIDHydrolase PF10230.9 CDJ83277.1 - 0.014 15.0 0.4 0.5 9.9 0.0 2.9 3 0 0 3 3 3 0 Lipid-droplet associated hydrolase Thiolase_N PF00108.23 CDJ83277.1 - 0.024 14.0 4.2 0.079 12.3 0.4 2.4 2 0 0 2 2 2 0 Thiolase, N-terminal domain Semialdhyde_dh PF01118.24 CDJ83277.1 - 0.044 14.2 0.2 0.31 11.5 0.1 2.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain GST_C PF00043.25 CDJ83277.1 - 0.045 14.0 0.0 8 6.8 0.0 4.0 4 0 0 4 4 3 0 Glutathione S-transferase, C-terminal domain Sacchrp_dh_NADP PF03435.18 CDJ83277.1 - 0.054 13.7 0.1 0.36 11.1 0.1 2.5 2 0 0 2 2 1 0 Saccharopine dehydrogenase NADP binding domain SpoVAD PF07451.11 CDJ83277.1 - 0.1 11.3 0.1 0.23 10.1 0.1 1.5 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) CNP_C_terminal PF17839.1 CDJ83277.1 - 0.12 13.1 0.7 60 4.4 0.0 3.9 5 0 0 5 5 2 0 C-terminal domain of cyclic nucleotide phosphodiesterase PGAP1 PF07819.13 CDJ83277.1 - 1.2 8.8 3.6 0.62 9.7 0.0 2.3 3 0 0 3 3 3 0 PGAP1-like protein Phospholip_B PF04916.13 CDJ83279.1 - 3.2e-165 550.7 0.1 3.7e-165 550.5 0.1 1.0 1 0 0 1 1 1 1 Phospholipase B PH PF00169.29 CDJ83280.1 - 1.2e-07 32.2 0.0 1.5e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 CDJ83280.1 - 0.0015 18.9 0.0 1.3 9.4 0.0 2.2 2 0 0 2 2 2 2 Pleckstrin homology domain P21-Arc PF04062.14 CDJ83281.1 - 9.5e-71 237.4 0.0 1.1e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit POPLD PF08170.12 CDJ83281.1 - 0.11 12.9 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 POPLD (NUC188) domain HBS1_N PF08938.10 CDJ83281.1 - 0.18 12.1 0.0 3.5 8.0 0.0 2.1 2 0 0 2 2 2 0 HBS1 N-terminus Neur_chan_memb PF02932.16 CDJ83282.1 - 0.3 11.1 5.2 0.39 10.8 5.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TMA7 PF09072.10 CDJ83282.1 - 1.9 9.4 6.4 1.4 9.8 4.0 2.1 1 1 1 2 2 2 0 Translation machinery associated TMA7 Glyco_trans_2_3 PF13632.6 CDJ83284.1 - 1.1e-41 142.9 1.8 1.1e-41 142.9 1.8 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CDJ83284.1 - 1.5e-07 31.5 0.0 2.3e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Fringe PF02434.16 CDJ83284.1 - 0.019 14.4 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Fringe-like TMEM154 PF15102.6 CDJ83285.1 - 0.00044 20.2 0.3 0.0059 16.5 0.3 2.1 2 0 0 2 2 2 1 TMEM154 protein family Syndecan PF01034.20 CDJ83285.1 - 0.027 14.4 2.0 0.032 14.1 0.8 1.7 2 0 0 2 2 2 0 Syndecan domain Tmemb_9 PF05434.11 CDJ83285.1 - 0.029 14.3 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 TMEM9 EphA2_TM PF14575.6 CDJ83285.1 - 0.06 14.2 0.0 0.23 12.4 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.12 CDJ83285.1 - 0.083 12.5 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family LAX PF15681.5 CDJ83285.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Lymphocyte activation family X AMA-1 PF02430.15 CDJ83285.1 - 0.13 11.2 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Apical membrane antigen 1 Vpu PF00558.19 CDJ83285.1 - 0.34 10.7 3.9 0.3 10.9 0.3 2.4 3 0 0 3 3 3 0 Vpu protein Recep_L_domain PF01030.24 CDJ83286.1 - 6.6e-10 39.1 0.3 9.9e-10 38.5 0.3 1.2 1 0 0 1 1 1 1 Receptor L domain EphA2_TM PF14575.6 CDJ83286.1 - 0.0029 18.4 0.4 0.0064 17.3 0.4 1.7 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 CDJ83286.1 - 0.025 14.4 0.1 0.051 13.4 0.1 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Orf78 PF06024.12 CDJ83286.1 - 0.031 14.6 1.3 0.031 14.6 1.3 2.2 1 1 1 2 2 2 0 Orf78 (ac78) Glycophorin_A PF01102.18 CDJ83286.1 - 0.043 14.0 1.8 0.054 13.7 0.7 1.6 1 1 0 1 1 1 0 Glycophorin A V_ATPase_I PF01496.19 CDJ83286.1 - 0.051 11.5 0.2 0.067 11.1 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4834 PF16118.5 CDJ83286.1 - 0.083 13.9 1.0 0.24 12.4 1.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) PRIMA1 PF16101.5 CDJ83286.1 - 0.093 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Herpes_gE PF02480.16 CDJ83286.1 - 0.1 11.4 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Zip PF02535.22 CDJ83286.1 - 0.11 11.7 0.2 0.16 11.2 0.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FAM176 PF14851.6 CDJ83286.1 - 0.15 11.7 3.2 1.1 9.0 3.2 2.1 1 1 0 1 1 1 0 FAM176 family DUF4736 PF15883.5 CDJ83286.1 - 0.18 11.5 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) Tmemb_9 PF05434.11 CDJ83286.1 - 0.22 11.4 0.2 0.42 10.5 0.2 1.4 1 1 0 1 1 1 0 TMEM9 OSTbeta PF15048.6 CDJ83286.1 - 0.32 11.1 3.0 1.6 8.9 3.0 2.1 1 1 0 1 1 1 0 Organic solute transporter subunit beta protein Baculo_11_kDa PF06143.11 CDJ83286.1 - 0.66 9.6 2.8 1.2 8.7 2.8 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family TMEM154 PF15102.6 CDJ83286.1 - 0.86 9.5 6.3 0.11 12.4 1.7 1.9 2 1 0 2 2 2 0 TMEM154 protein family PRK PF00485.18 CDJ83287.1 - 3.6e-43 147.6 0.0 4.3e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 CDJ83287.1 - 9.8e-07 29.4 0.0 1.5e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain CoaE PF01121.20 CDJ83287.1 - 8.6e-05 22.3 1.1 0.003 17.3 1.1 2.2 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_19 PF13245.6 CDJ83287.1 - 0.029 14.7 0.0 0.045 14.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CDJ83287.1 - 0.036 14.5 0.0 0.052 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 CDJ83287.1 - 0.042 13.1 0.0 0.08 12.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 CDJ83287.1 - 0.062 13.7 0.3 5.7 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 CDJ83287.1 - 0.066 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF2075 PF09848.9 CDJ83287.1 - 0.093 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PRK PF00485.18 CDJ83288.1 - 1.3e-46 158.9 0.0 1.5e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 CDJ83288.1 - 8.4e-05 23.1 0.0 0.00013 22.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain CoaE PF01121.20 CDJ83288.1 - 0.0015 18.3 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 2 Dephospho-CoA kinase DUF4852 PF16144.5 CDJ83288.1 - 0.0077 16.3 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4852) AAA_19 PF13245.6 CDJ83288.1 - 0.021 15.2 0.0 0.034 14.5 0.0 1.3 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CDJ83288.1 - 0.071 12.3 0.0 0.12 11.5 0.0 1.4 1 1 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.6 CDJ83288.1 - 0.14 12.6 0.0 14 6.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 CDJ83290.1 - 8.3e-21 74.5 0.1 1e-20 74.2 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.14 CDJ83290.1 - 5.3e-05 21.4 0.0 9.9e-05 20.5 0.0 1.4 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 CDJ83290.1 - 0.00028 20.7 0.2 0.00075 19.3 0.2 1.7 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 CDJ83290.1 - 0.00073 19.3 0.0 0.0065 16.2 0.0 2.0 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase 4HPAD_g_N PF18671.1 CDJ83290.1 - 0.021 14.5 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal PIF1 PF05970.14 CDJ83291.1 - 2.8e-63 214.3 0.0 3.8e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CDJ83291.1 - 2.4e-11 43.7 0.0 3.9e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ83291.1 - 1.7e-05 25.2 0.0 3.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CDJ83291.1 - 5.3e-05 23.3 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 CDJ83291.1 - 0.0035 17.4 0.0 0.0086 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CDJ83291.1 - 0.11 11.8 0.1 0.55 9.4 0.1 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 CDJ83291.1 - 0.11 12.9 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 CDJ83291.1 - 0.15 11.8 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 CDJ83291.1 - 0.17 11.9 0.1 0.58 10.1 0.0 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 CDJ83291.1 - 0.23 11.2 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Helitron_like_N PF14214.6 CDJ83292.1 - 1.3e-32 113.6 0.0 1.3e-32 113.6 0.0 2.5 2 1 0 2 2 2 1 Helitron helicase-like domain at N-terminus SRP-alpha_N PF04086.13 CDJ83292.1 - 8 6.3 21.4 15 5.4 21.4 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal 7TM_GPCR_Srv PF10323.9 CDJ83293.1 - 2e-16 60.2 15.2 2.6e-16 59.8 15.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Srg PF02118.21 CDJ83293.1 - 5.3e-12 46.0 15.8 7e-12 45.6 15.8 1.2 1 0 0 1 1 1 1 Srg family chemoreceptor 7TM_GPCR_Srx PF10328.9 CDJ83293.1 - 5.1e-06 26.3 14.5 8.4e-06 25.6 14.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 CDJ83293.1 - 2.5e-05 23.7 14.2 2.9e-05 23.5 13.8 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Sulfotransfer_4 PF17784.1 CDJ83293.1 - 0.076 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain AvrPtoB_bdg PF16847.5 CDJ83293.1 - 0.14 12.7 0.1 0.29 11.7 0.1 1.5 1 0 0 1 1 1 0 Avirulence AvrPtoB, BAK1-binding domain Collagen PF01391.18 CDJ83295.1 - 5.6e-22 77.3 92.3 1.2e-08 34.6 32.3 4.3 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ83295.1 - 2.1e-05 24.5 0.1 2.8e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain IF2_N PF04760.15 CDJ83297.1 - 0.032 14.0 0.1 0.13 12.1 0.1 1.9 1 1 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region eIF-1a PF01176.19 CDJ83298.1 - 8.6e-22 76.7 0.1 1.6e-21 75.9 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Nop14 PF04147.12 CDJ83298.1 - 0.15 10.2 15.9 0.19 9.9 15.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CDJ83298.1 - 0.21 9.9 8.3 0.2 9.9 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.13 CDJ83298.1 - 0.33 9.9 10.8 0.43 9.5 10.8 1.2 1 0 0 1 1 1 0 Paf1 VWA PF00092.28 CDJ83299.1 - 2.8e-91 304.5 4.6 1.9e-24 86.8 0.2 5.5 5 0 0 5 5 5 5 von Willebrand factor type A domain VWA_2 PF13519.6 CDJ83299.1 - 4.4e-48 162.4 6.6 5.4e-12 46.3 0.3 6.1 6 0 0 6 6 6 5 von Willebrand factor type A domain VWA_3 PF13768.6 CDJ83299.1 - 8e-19 68.1 4.7 0.00075 19.5 0.1 5.3 5 0 0 5 5 5 4 von Willebrand factor type A domain TssR PF17643.1 CDJ83299.1 - 0.16 9.9 0.0 0.28 9.1 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssR WD40 PF00400.32 CDJ83300.1 - 3.2e-40 135.4 23.7 1.3e-08 35.3 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ83300.1 - 6.8e-15 55.1 0.0 0.001 19.3 0.0 5.5 4 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CDJ83300.1 - 1.9e-05 24.2 0.0 0.11 11.9 0.0 3.1 1 1 2 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 CDJ83300.1 - 0.0015 17.5 0.1 1.1 8.1 0.0 3.2 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Ribosomal_L29 PF00831.23 CDJ83300.1 - 0.044 13.7 1.1 0.09 12.8 1.1 1.4 1 0 0 1 1 1 0 Ribosomal L29 protein ABC_membrane PF00664.23 CDJ83301.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region Peptidase_M1 PF01433.20 CDJ83302.1 - 1.1e-54 185.3 0.0 1.9e-54 184.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CDJ83302.1 - 7.6e-34 117.5 0.0 1.3e-33 116.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 CDJ83302.1 - 1.2e-05 25.0 0.7 2.5e-05 24.0 0.7 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain NOA36 PF06524.12 CDJ83303.1 - 2.6e-123 411.2 73.3 2e-122 408.3 73.3 1.9 1 1 0 1 1 1 1 NOA36 protein RVT_1 PF00078.27 CDJ83304.1 - 2.2e-09 37.2 0.0 3.8e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Methyltr_RsmF_N PF17125.5 CDJ83304.1 - 0.056 13.9 0.1 0.85 10.2 0.0 2.7 2 1 1 3 3 3 0 N-terminal domain of 16S rRNA methyltransferase RsmF Cation_ATPase_C PF00689.21 CDJ83305.1 - 7.6e-38 130.0 1.0 1e-37 129.6 1.0 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CDJ83305.1 - 7.8e-07 29.6 0.0 1.5e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDJ83305.1 - 0.054 13.2 0.1 0.079 12.7 0.1 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF5356 PF17309.2 CDJ83305.1 - 0.2 11.6 0.4 0.42 10.6 0.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5356) DUF2569 PF10754.9 CDJ83306.1 - 2.6 8.5 7.2 0.31 11.5 1.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) E1-E2_ATPase PF00122.20 CDJ83307.1 - 2e-36 125.2 2.1 2e-36 125.2 2.1 1.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 CDJ83307.1 - 1.5e-15 57.1 0.0 4.1e-15 55.6 0.0 1.8 1 1 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CDJ83307.1 - 3.6e-13 50.3 0.0 5.8e-12 46.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CDJ83307.1 - 2.7e-10 39.8 0.0 8.2e-10 38.2 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Rer1 PF03248.13 CDJ83307.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Rer1 family DUF4131 PF13567.6 CDJ83307.1 - 0.016 14.9 0.2 0.016 14.9 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3591 PF12157.8 CDJ83308.1 - 1e-141 472.6 0.0 1e-141 472.6 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 CDJ83308.1 - 6.5e-33 112.7 4.3 1.3e-16 60.4 0.7 2.8 2 0 0 2 2 2 2 Bromodomain zf-CCHC_6 PF15288.6 CDJ83308.1 - 0.00013 21.7 2.9 0.0004 20.2 2.9 1.8 1 0 0 1 1 1 1 Zinc knuckle Cytochrom_C550 PF14495.6 CDJ83308.1 - 0.083 12.6 0.1 0.27 11.0 0.1 1.8 1 0 0 1 1 1 0 Cytochrome c-550 domain Bap31_Bap29_C PF18035.1 CDJ83309.1 - 0.0033 17.4 1.5 0.03 14.3 0.2 3.0 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain Cep57_MT_bd PF06657.13 CDJ83309.1 - 0.044 14.2 1.9 0.039 14.4 4.4 2.2 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF4407 PF14362.6 CDJ83309.1 - 0.051 12.9 5.9 0.087 12.2 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prefoldin PF02996.17 CDJ83309.1 - 0.071 13.0 6.6 0.1 12.5 2.7 2.3 1 1 1 2 2 2 0 Prefoldin subunit LXG PF04740.12 CDJ83309.1 - 0.11 12.1 4.5 0.22 11.2 4.5 1.4 1 0 0 1 1 1 0 LXG domain of WXG superfamily Spc7 PF08317.11 CDJ83309.1 - 0.13 11.2 7.5 0.22 10.4 7.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 CDJ83309.1 - 0.29 11.2 2.1 0.73 9.9 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 CDJ83309.1 - 0.63 10.2 7.0 0.23 11.7 3.4 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family UPF0449 PF15136.6 CDJ83309.1 - 0.72 10.4 5.6 0.94 10.0 0.4 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 ISG65-75 PF11727.8 CDJ83309.1 - 1.2 8.3 6.6 2.9 7.1 6.6 1.6 1 0 0 1 1 1 0 Invariant surface glycoprotein MH2 PF03166.14 CDJ83310.1 - 1.6e-60 204.5 0.0 2.4e-60 203.9 0.0 1.3 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 CDJ83310.1 - 2.3e-22 79.1 2.4 4.5e-22 78.2 2.4 1.5 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 CDJ83310.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Interferon-regulatory factor 3 RhoGAP PF00620.27 CDJ83310.1 - 0.17 11.7 0.1 0.28 11.0 0.1 1.3 1 0 0 1 1 1 0 RhoGAP domain SNF PF00209.18 CDJ83311.1 - 6.9e-182 605.8 42.8 8.2e-182 605.5 42.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF5427 PF10310.9 CDJ83312.1 - 0.051 12.5 6.7 0.054 12.5 6.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) MAJIN PF15077.6 CDJ83312.1 - 0.14 12.0 6.4 0.16 11.7 6.4 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein Use1 PF09753.9 CDJ83312.1 - 0.37 10.5 7.6 0.51 10.0 7.6 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 RR_TM4-6 PF06459.12 CDJ83312.1 - 0.78 9.5 7.2 0.9 9.3 7.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 CDJ83312.1 - 2.6 6.2 9.1 2.8 6.1 9.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CDJ83312.1 - 3 6.5 6.2 2.9 6.6 6.2 1.0 1 0 0 1 1 1 0 Presenilin Collagen PF01391.18 CDJ83314.1 - 1.6e-19 69.4 111.8 9e-06 25.4 42.0 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ83314.1 - 3.1e-17 62.4 1.7 4.4e-17 61.9 1.7 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ83315.1 - 1e-19 70.0 112.0 1e-07 31.6 43.6 4.1 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ83315.1 - 5.9e-12 45.5 0.3 7.5e-12 45.1 0.3 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain E1-E2_ATPase PF00122.20 CDJ83316.1 - 3.2e-54 183.2 5.5 2e-53 180.6 0.2 2.8 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 CDJ83316.1 - 2.4e-44 151.2 6.0 2.4e-44 151.2 6.0 1.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CDJ83316.1 - 3.9e-22 78.2 0.0 7.4e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CDJ83316.1 - 4.9e-20 72.7 0.0 1.5e-19 71.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CDJ83316.1 - 4.1e-17 61.6 0.2 2.8e-16 59.0 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CDJ83316.1 - 9.5e-06 25.5 1.2 2.6e-05 24.1 1.2 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CDJ83316.1 - 5.8e-05 23.6 0.0 0.00028 21.3 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HTH_48 PF17906.1 CDJ83317.1 - 0.058 13.5 0.0 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 HTH domain in Mos1 transposase zf-NOSIP PF15906.5 CDJ83318.1 - 2.8e-36 123.5 0.2 5e-36 122.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 CDJ83318.1 - 2.3e-08 33.7 7.4 0.00084 18.8 0.1 3.0 2 2 1 3 3 3 2 Rtf2 RING-finger U-box PF04564.15 CDJ83318.1 - 9.1e-06 25.8 0.0 0.0008 19.5 0.0 2.5 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.8 CDJ83318.1 - 0.00056 19.7 0.3 0.0054 16.5 0.0 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit HECW_N PF16562.5 CDJ83318.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 MRP-S24 PF14955.6 CDJ83318.1 - 0.16 11.9 0.5 0.44 10.5 0.1 1.8 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S24 ARS2 PF04959.13 CDJ83318.1 - 0.62 10.4 7.7 3.3 8.0 0.1 2.6 2 2 0 2 2 2 0 Arsenite-resistance protein 2 CD34_antigen PF06365.12 CDJ83319.1 - 0.0037 16.9 0.1 0.0051 16.4 0.1 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family BAR PF03114.18 CDJ83320.1 - 7.5e-14 51.9 8.1 8.8e-14 51.7 8.1 1.0 1 0 0 1 1 1 1 BAR domain DUF2997 PF11211.8 CDJ83320.1 - 0.12 12.2 0.2 3.2 7.6 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2997) 4HB_MCP_1 PF12729.7 CDJ83320.1 - 0.47 10.0 5.0 3.5 7.1 0.1 2.2 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction SIP1 PF04938.12 CDJ83321.1 - 8e-31 107.5 0.0 2.7e-30 105.7 0.0 1.5 1 1 1 2 2 2 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) DnaJ PF00226.31 CDJ83322.1 - 9.6e-24 83.3 2.4 1.2e-23 83.0 2.4 1.1 1 0 0 1 1 1 1 DnaJ domain SabA_adhesion PF18304.1 CDJ83322.1 - 0.0094 15.2 0.1 0.0099 15.2 0.1 1.1 1 0 0 1 1 1 1 SabA N-terminal extracellular adhesion domain Caerin_1 PF07440.12 CDJ83323.1 - 0.14 12.3 1.5 0.24 11.5 1.5 1.3 1 0 0 1 1 1 0 Caerin 1 protein BTB_2 PF02214.22 CDJ83324.1 - 3.3e-09 37.0 0.0 5.7e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain PBD PF00786.28 CDJ83324.1 - 8.4e-06 26.1 0.2 1.6e-05 25.1 0.2 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain Na_sulph_symp PF00939.19 CDJ83325.1 - 2.6e-75 254.3 20.5 3.2e-75 254.0 20.5 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CDJ83325.1 - 7.1e-36 123.9 38.9 1.4e-27 96.7 15.6 2.8 1 1 1 2 2 2 2 Citrate transporter GntP_permease PF02447.16 CDJ83325.1 - 1.7e-05 23.7 15.5 6.8e-05 21.7 6.8 2.3 2 0 0 2 2 2 2 GntP family permease Carb_kinase PF01256.17 CDJ83326.1 - 1.4e-62 211.4 0.0 1.6e-62 211.2 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase DUF4516 PF14990.6 CDJ83326.1 - 0.032 14.0 0.1 0.094 12.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) Pkinase PF00069.25 CDJ83327.1 - 2.4e-29 102.5 0.0 5.4e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ83327.1 - 1.5e-14 53.9 0.0 3.8e-14 52.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ83327.1 - 0.064 12.0 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Snapin_Pallidin PF14712.6 CDJ83327.1 - 0.094 13.1 2.6 4.5 7.8 0.1 2.7 2 0 0 2 2 2 0 Snapin/Pallidin DegS PF05384.11 CDJ83327.1 - 0.91 9.0 9.0 3.9 6.9 0.2 3.1 3 0 0 3 3 3 0 Sensor protein DegS DEAD PF00270.29 CDJ83328.1 - 2.8e-16 59.8 0.0 5.6e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ83328.1 - 1.7e-11 44.4 0.0 5e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDJ83328.1 - 1.4e-07 31.8 0.0 9e-07 29.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HBD PF18534.1 CDJ83328.1 - 0.079 13.1 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Helical bundle domain MAM33 PF02330.16 CDJ83329.1 - 5.5e-24 85.3 0.0 7.3e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF3872 PF12988.7 CDJ83329.1 - 0.057 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3872) Y_phosphatase PF00102.27 CDJ83330.1 - 3.4e-74 249.4 0.0 4.2e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ83330.1 - 1.1e-05 25.2 0.5 4.6e-05 23.2 0.1 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDJ83330.1 - 0.0082 16.1 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 CDJ83330.1 - 0.084 12.4 0.2 0.18 11.4 0.1 1.6 1 1 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CDJ83330.1 - 0.14 12.3 0.0 0.47 10.6 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate TylF PF05711.11 CDJ83330.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) HECT PF00632.25 CDJ83332.1 - 1e-87 294.5 0.0 1.3e-87 294.2 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) eIF3_subunit PF08597.10 CDJ83334.1 - 0.00027 21.0 7.1 0.00033 20.7 7.1 1.2 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit MCCD1 PF15707.5 CDJ83334.1 - 0.11 13.0 2.9 0.14 12.6 2.3 1.5 1 1 0 1 1 1 0 Mitochondrial coiled-coil domain protein 1 DGF-1_C PF11040.8 CDJ83334.1 - 2.5 8.2 7.1 4.5 7.3 0.4 2.2 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus FA_hydroxylase PF04116.13 CDJ83335.1 - 2.1e-22 79.9 7.2 2.1e-22 79.9 7.2 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Adap_comp_sub PF00928.21 CDJ83337.1 - 0.085 12.2 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Adaptor complexes medium subunit family BIR PF00653.21 CDJ83339.1 - 0.06 14.0 2.3 0.32 11.7 1.8 2.2 1 1 1 2 2 2 0 Inhibitor of Apoptosis domain zf-C2H2_2 PF12756.7 CDJ83339.1 - 0.06 13.7 3.8 0.22 11.9 3.8 1.9 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 CDJ83339.1 - 0.16 12.3 5.7 0.4 11.0 1.1 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 CDJ83339.1 - 0.43 11.1 10.6 2.5 8.7 0.1 4.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ83339.1 - 1.1 10.3 14.2 4.7 8.3 0.1 4.4 4 1 0 4 4 4 0 C2H2-type zinc finger FAM104 PF15434.6 CDJ83339.1 - 1.6 9.3 20.2 4.1 8.0 4.6 2.5 2 0 0 2 2 2 0 Family 104 zf-C2H2_6 PF13912.6 CDJ83339.1 - 3 7.9 8.5 0.45 10.6 0.7 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HE PF16278.5 CDJ83339.1 - 8.3 6.9 6.9 7.2 7.1 0.3 3.3 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger MIP PF00230.20 CDJ83340.1 - 0.0019 17.9 9.2 0.023 14.4 3.8 2.2 1 1 0 2 2 2 2 Major intrinsic protein RRM_1 PF00076.22 CDJ83341.1 - 2.7e-26 91.2 0.0 5.5e-15 55.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 CDJ83341.1 - 0.00037 20.1 0.1 0.00091 18.8 0.0 1.6 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated RRM_7 PF16367.5 CDJ83341.1 - 0.002 18.2 0.0 1.4 9.1 0.0 3.3 2 2 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 CDJ83341.1 - 0.0029 17.6 0.0 0.45 10.5 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 CDJ83341.1 - 0.01 15.5 0.2 0.27 10.9 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain RRM_5 PF13893.6 CDJ83341.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DDE_Tnp_1_7 PF13843.6 CDJ83342.1 - 5.8e-88 295.5 0.5 7.9e-88 295.1 0.5 1.2 1 0 0 1 1 1 1 Transposase IS4 IBR PF01485.21 CDJ83342.1 - 0.018 15.3 9.3 0.39 11.0 8.2 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain EGF PF00008.27 CDJ83348.1 - 0.0015 18.8 24.8 0.091 13.1 1.4 4.0 3 1 0 3 3 3 3 EGF-like domain EGF_2 PF07974.13 CDJ83348.1 - 0.0019 18.5 44.4 0.2 12.0 8.3 4.5 3 1 1 4 4 4 4 EGF-like domain hEGF PF12661.7 CDJ83348.1 - 0.03 15.0 0.5 0.03 15.0 0.5 4.9 4 0 0 4 4 4 0 Human growth factor-like EGF Laminin_EGF PF00053.24 CDJ83348.1 - 0.76 10.0 30.0 4.5 7.5 7.8 4.5 2 2 2 4 4 4 0 Laminin EGF domain Bunya_NS-S PF01104.17 CDJ83349.1 - 0.085 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-s TB2_DP1_HVA22 PF03134.19 CDJ83350.1 - 0.0012 18.7 2.9 0.0012 18.7 2.9 1.7 1 1 0 1 1 1 1 TB2/DP1, HVA22 family SPP PF06550.11 CDJ83350.1 - 0.028 13.9 2.0 0.036 13.6 2.0 1.1 1 0 0 1 1 1 0 Signal-peptide peptidase, presenilin aspartyl protease Zip PF02535.22 CDJ83351.1 - 1e-55 189.3 9.7 1.2e-55 189.1 9.7 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Mito_carr PF00153.27 CDJ83352.1 - 1.4e-63 210.9 3.0 2.8e-22 78.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_47 PF01532.20 CDJ83353.1 - 5.7e-112 374.9 0.0 9.8e-112 374.2 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 MCU PF04678.13 CDJ83354.1 - 3.9e-09 36.8 0.0 5.5e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial calcium uniporter RVT_1 PF00078.27 CDJ83355.1 - 5.8e-18 65.2 0.0 1.2e-07 31.5 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) PC_rep PF01851.22 CDJ83356.1 - 3.5e-05 24.0 0.9 0.0006 20.1 0.0 3.1 3 0 0 3 3 3 1 Proteasome/cyclosome repeat phiKZ_IP PF12699.7 CDJ83356.1 - 0.0043 16.3 0.1 0.0079 15.4 0.1 1.4 1 0 0 1 1 1 1 phiKZ-like phage internal head proteins RVT_1 PF00078.27 CDJ83357.1 - 0.0047 16.5 0.0 0.0094 15.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pmp3 PF01679.17 CDJ83358.1 - 5.2e-20 71.4 10.4 7.6e-20 70.9 10.4 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator MIG-14_Wnt-bd PF06664.12 CDJ83358.1 - 0.021 14.1 0.1 0.022 14.0 0.1 1.2 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion CPSF_A PF03178.15 CDJ83361.1 - 2e-70 237.6 0.0 9.1e-70 235.5 0.0 2.1 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.9 CDJ83361.1 - 1.6e-41 142.5 0.0 2.8e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF775 PF05603.12 CDJ83362.1 - 5.2e-40 137.1 0.0 8.2e-40 136.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF775) RRM_1 PF00076.22 CDJ83362.1 - 2.6e-30 104.0 0.2 1.6e-15 56.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ83362.1 - 0.00017 21.6 0.1 0.15 12.2 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CDJ83362.1 - 0.00021 21.2 0.3 0.22 11.6 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Collagen PF01391.18 CDJ83363.1 - 8.9e-24 83.0 104.8 2.3e-10 40.1 35.0 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ83363.1 - 5.9e-10 39.1 0.2 7.3e-10 38.8 0.2 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain CPSF_A PF03178.15 CDJ83364.1 - 2e-70 237.6 0.0 9.1e-70 235.5 0.0 2.1 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.9 CDJ83364.1 - 1.6e-41 142.5 0.0 2.8e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF775 PF05603.12 CDJ83365.1 - 5.2e-40 137.1 0.0 8.2e-40 136.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF775) RRM_1 PF00076.22 CDJ83365.1 - 2.6e-30 104.0 0.2 1.6e-15 56.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ83365.1 - 0.00017 21.6 0.1 0.15 12.2 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CDJ83365.1 - 0.00021 21.2 0.3 0.22 11.6 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Collagen PF01391.18 CDJ83366.1 - 2.9e-26 91.0 111.8 4.1e-10 39.3 35.8 4.0 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ83366.1 - 5.9e-10 39.1 0.2 7.3e-10 38.8 0.2 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain MAM PF00629.23 CDJ83367.1 - 0.00078 19.4 6.1 0.22 11.5 0.1 3.1 4 0 0 4 4 4 2 MAM domain, meprin/A5/mu PrmA PF06325.13 CDJ83368.1 - 2.4e-12 46.9 0.0 3.8e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CDJ83368.1 - 1.2e-08 35.6 0.0 3.8e-08 33.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ83368.1 - 8.9e-07 28.8 0.0 2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 CDJ83368.1 - 3.5e-06 26.9 0.0 5.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 CDJ83368.1 - 7.3e-06 25.9 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ83368.1 - 2.9e-05 23.7 0.0 5.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 CDJ83368.1 - 4.4e-05 22.7 0.0 7.2e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 CDJ83368.1 - 8.7e-05 22.4 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 CDJ83368.1 - 0.00013 22.6 0.0 0.00044 20.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 CDJ83368.1 - 0.00055 19.9 0.0 0.0017 18.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CDJ83368.1 - 0.0012 18.5 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 CMAS PF02353.20 CDJ83368.1 - 0.015 14.6 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase GLTSCR1 PF15249.6 CDJ83369.1 - 1.4e-18 67.2 2.3 6.8e-18 65.0 2.3 2.3 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein Ribosomal_S17_N PF16205.5 CDJ83370.1 - 4.7e-29 100.6 0.1 1e-28 99.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 CDJ83370.1 - 2.7e-25 88.3 0.2 4e-25 87.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 PRF PF06875.11 CDJ83370.1 - 0.17 11.3 0.1 0.25 10.7 0.1 1.2 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF Vps54 PF07928.12 CDJ83371.1 - 0.086 13.3 0.1 19 5.7 0.0 3.3 2 0 0 2 2 2 0 Vps54-like protein SIR2 PF02146.17 CDJ83372.1 - 3.1e-22 79.4 0.0 1.1e-14 54.8 0.0 2.5 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 CDJ83372.1 - 0.00074 19.3 0.0 0.04 13.6 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain NUC153 PF08159.12 CDJ83373.1 - 5.9e-06 26.0 5.6 9.2e-06 25.4 0.0 3.4 3 0 0 3 3 3 1 NUC153 domain tRNA-synt_1g PF09334.11 CDJ83374.1 - 6.3e-150 499.3 0.8 8.6e-150 498.8 0.8 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA_bind PF01588.20 CDJ83374.1 - 2.6e-31 107.6 0.1 5.3e-31 106.6 0.1 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1 PF00133.22 CDJ83374.1 - 1.8e-09 36.4 0.2 6e-07 28.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDJ83374.1 - 0.0038 17.2 0.0 0.01 15.8 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CDJ83374.1 - 0.15 11.4 2.3 0.24 10.7 0.0 2.3 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain zinc-ribbons_6 PF07191.12 CDJ83374.1 - 2.7 8.0 7.0 11 6.1 7.0 2.0 1 1 0 1 1 1 0 zinc-ribbons zf-C2HC5 PF06221.13 CDJ83374.1 - 4.4 7.4 6.4 14 5.7 1.1 2.5 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type ShK PF01549.24 CDJ83375.1 - 1.8e-05 25.2 5.3 2.5e-05 24.7 5.3 1.2 1 0 0 1 1 1 1 ShK domain-like Phage_holin_3_6 PF07332.11 CDJ83376.1 - 0.028 14.5 0.1 0.028 14.5 0.1 4.0 5 0 0 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III DUF996 PF06195.13 CDJ83376.1 - 5 7.4 11.7 0.13 12.5 1.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF996) DUF1287 PF06940.11 CDJ83378.1 - 0.032 13.9 0.0 0.041 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) Gp-FAR-1 PF05823.12 CDJ83378.1 - 0.055 13.8 1.1 0.22 11.9 0.3 1.8 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Ldh_1_C PF02866.18 CDJ83379.1 - 2.4e-23 82.9 0.0 2.6e-23 82.8 0.0 1.0 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain DeoC PF01791.9 CDJ83380.1 - 2.4e-36 125.5 0.6 4.6e-36 124.6 0.2 1.7 2 0 0 2 2 2 1 DeoC/LacD family aldolase AMP-binding PF00501.28 CDJ83380.1 - 2.8e-31 108.6 0.2 8.6e-30 103.7 0.0 2.6 1 1 1 2 2 2 1 AMP-binding enzyme PQQ_3 PF13570.6 CDJ83380.1 - 9.3e-11 41.9 0.1 0.00015 22.1 0.0 6.0 7 0 0 7 7 7 2 PQQ-like domain PQQ_2 PF13360.6 CDJ83380.1 - 7.3e-10 38.8 0.0 0.00013 21.7 0.0 2.4 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.21 CDJ83380.1 - 6e-07 29.1 0.2 0.047 13.6 0.0 4.0 4 0 0 4 4 4 2 PQQ enzyme repeat Glycos_transf_1 PF00534.20 CDJ83381.1 - 4.6e-36 123.9 0.0 8.1e-36 123.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CDJ83381.1 - 1.6e-17 64.2 0.0 2.8e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CDJ83381.1 - 1.5e-14 54.3 0.0 2.5e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 CDJ83381.1 - 8.1e-05 23.1 0.0 0.00017 22.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 CDJ83381.1 - 0.00047 20.5 0.0 0.00098 19.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_5 PF16994.5 CDJ83381.1 - 0.0025 17.4 0.0 0.042 13.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl-transferase family 4 ALG11_N PF15924.5 CDJ83381.1 - 0.0077 16.3 1.5 8.4 6.4 0.6 3.2 1 1 1 2 2 2 1 ALG11 mannosyltransferase N-terminus Glyco_trans_4_2 PF13477.6 CDJ83381.1 - 0.018 15.1 0.1 0.097 12.7 0.1 2.0 2 0 0 2 2 2 0 Glycosyl transferase 4-like AhpC-TSA PF00578.21 CDJ83382.1 - 4e-40 136.6 0.1 8.1e-40 135.6 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 CDJ83382.1 - 7.5e-17 61.4 0.0 1.1e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CDJ83382.1 - 1.4e-13 50.4 0.1 5.6e-13 48.5 0.1 2.0 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin Lebercilin PF15619.6 CDJ83383.1 - 0.00068 19.3 5.4 0.00096 18.9 5.4 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease DUF4795 PF16043.5 CDJ83383.1 - 0.0074 15.9 2.5 0.0097 15.5 2.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) DHR10 PF18595.1 CDJ83383.1 - 0.011 15.8 5.6 0.016 15.2 5.6 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain AAA_13 PF13166.6 CDJ83383.1 - 0.012 14.3 0.7 0.015 14.0 0.7 1.0 1 0 0 1 1 1 0 AAA domain UPF0242 PF06785.11 CDJ83383.1 - 0.015 15.4 0.2 0.015 15.4 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Phage_GP20 PF06810.11 CDJ83383.1 - 0.028 14.2 2.1 0.04 13.7 2.1 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 HMMR_N PF15905.5 CDJ83383.1 - 0.033 13.7 3.9 0.041 13.3 3.9 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal AAA_32 PF13654.6 CDJ83383.1 - 0.04 12.7 0.4 0.047 12.5 0.4 1.0 1 0 0 1 1 1 0 AAA domain CM_2 PF01817.21 CDJ83383.1 - 0.046 14.1 1.2 0.066 13.6 1.2 1.2 1 0 0 1 1 1 0 Chorismate mutase type II Laminin_II PF06009.12 CDJ83383.1 - 0.048 13.7 0.6 0.067 13.2 0.6 1.2 1 0 0 1 1 1 0 Laminin Domain II DUF4337 PF14235.6 CDJ83383.1 - 0.13 12.4 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) APG6_N PF17675.1 CDJ83383.1 - 0.33 11.5 6.5 0.45 11.0 6.5 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region TolA_bind_tri PF16331.5 CDJ83383.1 - 0.46 10.6 7.6 0.73 10.0 7.6 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation Peptidase_C1 PF00112.23 CDJ83384.1 - 3.2e-64 217.0 9.9 3.6e-64 216.8 9.9 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ83384.1 - 0.37 9.5 4.5 0.24 10.1 0.6 2.0 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ83385.1 - 7.5e-65 219.1 4.0 7.5e-65 219.1 4.0 1.5 2 0 0 2 2 2 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ83385.1 - 0.0037 16.1 1.5 0.012 14.5 0.3 2.0 2 0 0 2 2 2 1 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ83386.1 - 1.1e-61 208.8 4.1 1.4e-61 208.4 4.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ83386.1 - 0.24 10.1 4.8 0.055 12.2 0.9 1.7 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ83387.1 - 3.2e-64 217.0 7.3 3.9e-64 216.7 7.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ83387.1 - 0.052 12.3 3.0 0.051 12.3 0.5 1.9 2 0 0 2 2 2 0 Peptidase C1-like family Trm5_N PF18093.1 CDJ83387.1 - 0.076 12.9 0.5 0.83 9.6 0.2 2.3 2 0 0 2 2 2 0 tRNA methyltransferase 5 N-terminal domain Peptidase_C1 PF00112.23 CDJ83388.1 - 1.2e-64 218.4 8.8 1.6e-64 218.0 8.8 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ83388.1 - 0.13 11.0 4.5 0.074 11.8 0.9 2.0 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ83389.1 - 3.6e-67 226.6 9.5 4.4e-67 226.3 9.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ83389.1 - 0.015 14.1 0.3 0.015 14.1 0.3 1.9 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C39_2 PF13529.6 CDJ83389.1 - 0.057 14.0 0.0 0.091 13.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase_C39 like family Peptidase_C1 PF00112.23 CDJ83390.1 - 5.7e-62 209.7 9.8 7.1e-62 209.3 9.8 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1 PF00112.23 CDJ83391.1 - 7.7e-63 212.5 1.6 9.6e-63 212.2 1.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ83391.1 - 0.28 9.9 0.9 0.77 8.5 0.1 1.8 2 0 0 2 2 2 0 Peptidase C1-like family RVT_1 PF00078.27 CDJ83392.1 - 1.1e-12 48.0 0.0 1.3e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CDJ83393.1 - 9.4e-08 31.8 0.0 2.2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CDJ83393.1 - 0.15 11.5 0.0 0.34 10.4 0.0 1.6 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Peptidase_C1 PF00112.23 CDJ83394.1 - 1.4e-65 221.5 3.6 1.8e-65 221.1 3.6 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ83394.1 - 1.5 7.5 5.0 0.26 10.0 0.4 1.9 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ83395.1 - 8.4e-71 238.5 11.7 1e-70 238.3 11.7 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ83395.1 - 0.23 10.2 3.7 0.15 10.8 0.4 1.9 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ83397.1 - 7.9e-64 215.7 8.9 9.8e-64 215.4 8.9 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1 PF00112.23 CDJ83398.1 - 2.3e-64 217.5 5.6 3e-64 217.1 5.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ83398.1 - 0.049 12.4 0.3 0.079 11.7 0.3 1.2 1 0 0 1 1 1 0 Peptidase C1-like family DUF5341 PF17276.2 CDJ83398.1 - 0.068 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5341) Peptidase_C1 PF00112.23 CDJ83399.1 - 4.9e-68 229.5 8.8 6.5e-68 229.1 8.8 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ83399.1 - 0.004 16.0 2.0 0.014 14.2 0.3 2.1 2 0 0 2 2 2 1 Peptidase C1-like family cNMP_binding PF00027.29 CDJ83400.1 - 1.1e-10 41.4 0.0 2.2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 CDJ83400.1 - 0.053 13.5 0.8 0.1 12.5 0.8 1.5 1 0 0 1 1 1 0 Ion channel Ig_3 PF13927.6 CDJ83402.1 - 1.1e-17 64.3 0.0 4.1e-08 33.7 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 CDJ83402.1 - 2.3e-12 46.8 0.0 3.2e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 CDJ83402.1 - 5.2e-11 42.6 0.0 3.8e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 CDJ83402.1 - 2e-10 40.9 0.0 2.8e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 CDJ83402.1 - 8.2e-07 29.2 0.2 0.16 12.2 0.0 3.5 2 2 0 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDJ83402.1 - 0.022 14.8 0.2 0.68 10.0 0.0 2.8 2 1 1 3 3 3 0 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 CDJ83402.1 - 0.039 13.5 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain EGF_CA PF07645.15 CDJ83403.1 - 2.6e-23 82.0 44.8 1.4e-10 41.2 9.8 5.0 4 2 0 4 4 4 3 Calcium-binding EGF domain cEGF PF12662.7 CDJ83403.1 - 3.8e-16 58.7 13.0 1.5e-10 40.8 1.5 4.0 4 0 0 4 4 4 2 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CDJ83403.1 - 1.7e-14 53.8 40.2 8.5e-09 35.6 5.4 4.4 4 0 0 4 4 4 2 Coagulation Factor Xa inhibitory site EGF PF00008.27 CDJ83403.1 - 1.9e-05 24.8 3.9 1.9e-05 24.8 3.9 4.8 5 0 0 5 5 5 2 EGF-like domain EGF_MSP1_1 PF12946.7 CDJ83403.1 - 0.00085 19.3 0.5 0.00085 19.3 0.5 3.5 3 0 0 3 3 3 2 MSP1 EGF domain 1 hEGF PF12661.7 CDJ83403.1 - 0.0015 19.1 35.9 0.0088 16.6 2.0 5.1 6 0 0 6 6 6 2 Human growth factor-like EGF EGF_3 PF12947.7 CDJ83403.1 - 0.0023 18.1 37.3 0.0065 16.7 5.5 4.2 4 0 0 4 4 4 2 EGF domain Plasmod_Pvs28 PF06247.11 CDJ83403.1 - 1 9.7 32.7 0.26 11.6 7.6 3.9 3 0 0 3 3 3 0 Pvs28 EGF domain EGF_CA PF07645.15 CDJ83405.1 - 4.1e-48 161.3 64.3 1.5e-11 44.3 7.7 5.9 5 1 1 6 6 6 5 Calcium-binding EGF domain cEGF PF12662.7 CDJ83405.1 - 1.8e-21 75.7 45.7 7.3e-07 29.0 2.2 7.0 7 0 0 7 7 7 5 Complement Clr-like EGF-like EGF_3 PF12947.7 CDJ83405.1 - 2.3e-12 46.9 48.8 1.2e-05 25.4 5.5 7.1 4 2 1 5 5 5 5 EGF domain FXa_inhibition PF14670.6 CDJ83405.1 - 2.2e-08 34.2 59.0 1e-05 25.7 4.3 6.8 3 1 3 6 6 6 3 Coagulation Factor Xa inhibitory site EGF PF00008.27 CDJ83405.1 - 0.00019 21.6 50.9 0.0036 17.6 3.1 8.1 5 4 1 6 6 6 3 EGF-like domain hEGF PF12661.7 CDJ83405.1 - 0.0019 18.8 47.9 0.0042 17.7 1.6 9.6 9 1 0 9 9 9 2 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CDJ83405.1 - 0.0059 16.6 6.2 0.0059 16.6 6.2 5.8 5 1 1 6 6 6 2 MSP1 EGF domain 1 RANK_CRD_2 PF18278.1 CDJ83405.1 - 0.088 13.0 8.3 1.7 8.9 0.2 4.7 4 0 0 4 4 4 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 PQQ_2 PF13360.6 CDJ83406.1 - 5.8e-05 22.8 0.0 0.00025 20.7 0.0 1.8 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.21 CDJ83406.1 - 0.0014 18.5 0.9 0.0057 16.5 0.1 2.5 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_3 PF13570.6 CDJ83406.1 - 0.17 12.4 1.3 49 4.6 0.1 3.9 4 0 0 4 4 4 0 PQQ-like domain Peptidase_C48 PF02902.19 CDJ83407.1 - 6.3e-29 101.4 1.4 8.1e-29 101.0 1.4 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Herpes_U26 PF07402.11 CDJ83407.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Human herpesvirus U26 protein TPR_1 PF00515.28 CDJ83410.1 - 4.7e-30 102.2 10.0 4.1e-06 26.4 0.0 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ83410.1 - 5.7e-30 101.0 14.7 2.6e-07 30.3 0.0 8.0 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ83410.1 - 1.6e-29 99.6 19.1 2.8e-05 23.9 0.0 9.8 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ83410.1 - 5.8e-26 89.9 9.3 8.5e-06 25.4 0.0 6.9 5 2 2 7 7 7 4 TPR repeat TPR_12 PF13424.6 CDJ83410.1 - 5.6e-21 74.6 17.8 2.2e-08 34.2 0.2 7.2 5 3 2 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ83410.1 - 6.7e-20 71.4 12.3 0.00024 21.5 0.2 6.1 5 2 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ83410.1 - 3.8e-19 67.7 3.9 0.00011 22.8 0.2 7.4 5 3 3 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ83410.1 - 6.9e-14 50.8 4.5 0.00089 19.1 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ83410.1 - 4.5e-12 45.8 15.9 0.011 16.4 0.0 8.9 8 2 1 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ83410.1 - 9.3e-12 45.4 11.8 0.00087 19.9 0.1 6.1 6 2 0 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ83410.1 - 5.4e-11 42.1 20.7 0.012 15.9 0.0 8.8 9 1 1 10 10 9 3 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ83410.1 - 2.3e-09 36.8 13.3 0.013 15.3 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ83410.1 - 3.6e-09 36.7 12.6 9.9e-05 22.5 1.2 4.4 2 2 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CDJ83410.1 - 1e-08 35.2 1.8 0.029 14.5 0.2 4.9 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 CDJ83410.1 - 2.1e-07 30.4 4.4 0.063 12.5 0.2 4.6 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 CDJ83410.1 - 8.5e-05 22.8 3.6 0.24 11.8 0.1 3.3 4 1 0 4 4 3 2 Tetratricopeptide repeat NARP1 PF12569.8 CDJ83410.1 - 0.00033 19.7 2.6 0.68 8.8 0.0 3.4 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_MalT PF17874.1 CDJ83410.1 - 0.0021 17.5 8.2 0.019 14.3 0.9 3.7 1 1 2 3 3 3 1 MalT-like TPR region BTAD PF03704.17 CDJ83410.1 - 0.0083 16.6 4.9 11 6.4 0.0 4.1 3 1 1 4 4 4 0 Bacterial transcriptional activator domain TPR_21 PF09976.9 CDJ83410.1 - 0.034 13.9 3.6 2.5 7.8 0.5 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat-like domain PknG_TPR PF16918.5 CDJ83410.1 - 0.11 11.2 0.1 0.24 10.1 0.1 1.5 1 1 0 1 1 1 0 Protein kinase G tetratricopeptide repeat TPR_4 PF07721.14 CDJ83410.1 - 0.12 13.0 3.7 54 4.8 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ83410.1 - 0.12 12.4 2.6 23 5.1 0.0 4.2 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF1647 PF07801.11 CDJ83411.1 - 6.1e-08 32.5 0.1 1.4e-07 31.3 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1647) DUF1647 PF07801.11 CDJ83412.1 - 5.1e-36 123.5 0.0 1.2e-35 122.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1647) DUF1647 PF07801.11 CDJ83413.1 - 7.7e-37 126.2 0.0 1.1e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) EVI2A PF05399.11 CDJ83413.1 - 2 7.9 3.3 3.2 7.3 3.3 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) DnaJ PF00226.31 CDJ83414.1 - 8.5e-05 22.6 0.0 0.00014 22.0 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 CDJ83414.1 - 0.0012 18.9 0.0 0.0016 18.5 0.0 1.1 1 0 0 1 1 1 1 Pam16 Peptidase_C50 PF03568.17 CDJ83415.1 - 1.2e-62 212.3 0.0 2.3e-62 211.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C50 ANAPC3 PF12895.7 CDJ83415.1 - 0.0038 17.4 0.3 0.015 15.5 0.3 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CDJ83415.1 - 0.0077 16.0 0.5 0.026 14.4 0.5 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat Peptidase_C50 PF03568.17 CDJ83417.1 - 2.6e-63 214.5 0.0 7e-63 213.1 0.0 1.7 1 1 0 1 1 1 1 Peptidase family C50 Ig_3 PF13927.6 CDJ83418.1 - 0.0002 21.9 0.3 0.76 10.4 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 CDJ83418.1 - 0.00029 21.1 0.7 0.82 10.0 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 CDJ83418.1 - 0.018 15.1 0.7 0.16 12.0 0.0 2.6 2 2 1 3 3 3 0 Immunoglobulin I-set domain V-set PF07686.17 CDJ83418.1 - 0.37 11.0 2.2 0.89 9.7 0.0 2.4 3 1 0 3 3 3 0 Immunoglobulin V-set domain PBD PF00786.28 CDJ83419.1 - 1.3e-05 25.5 0.0 4e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain SCVP PF17619.2 CDJ83420.1 - 2.6e-22 79.5 0.0 3e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Secreted clade V proteins ChAPs PF09295.10 CDJ83420.1 - 0.15 11.0 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) Nup84_Nup100 PF04121.13 CDJ83423.1 - 5.9e-23 80.9 0.3 3.1e-18 65.3 0.0 2.5 2 1 0 2 2 2 2 Nuclear pore protein 84 / 107 CRAL_TRIO PF00650.20 CDJ83424.1 - 9.1e-17 61.2 0.2 1.4e-16 60.6 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain DUF2939 PF11159.8 CDJ83425.1 - 0.21 12.0 0.1 31 5.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) 7tm_1 PF00001.21 CDJ83426.1 - 4.3e-13 49.2 8.8 7.9e-13 48.3 8.8 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDJ83426.1 - 1.2e-06 28.1 9.7 2.3e-06 27.1 9.7 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 CDJ83426.1 - 1.2 8.7 9.7 0.37 10.4 6.4 1.8 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx CAP PF00188.26 CDJ83429.1 - 0.0084 16.9 0.0 0.03 15.2 0.0 1.8 1 1 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CDJ83430.1 - 0.0085 16.9 0.0 0.029 15.2 0.0 1.8 1 1 0 1 1 1 1 Cysteine-rich secretory protein family RNase_T PF00929.24 CDJ83431.1 - 1.3e-31 110.3 0.0 1.8e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Exonuclease B12D PF06522.11 CDJ83432.1 - 0.089 12.6 0.4 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit FMO-like PF00743.19 CDJ83433.1 - 4.7e-156 520.3 0.0 5.9e-156 520.0 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CDJ83433.1 - 2.9e-19 69.5 0.0 4e-16 59.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CDJ83433.1 - 7.1e-12 45.2 0.0 2.1e-09 37.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CDJ83433.1 - 1.6e-07 30.8 0.2 3.2e-06 26.5 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 CDJ83433.1 - 3.4e-07 30.4 0.1 3.4e-05 23.9 0.0 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 CDJ83433.1 - 8.8e-06 25.5 0.1 0.0017 18.0 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 CDJ83433.1 - 4.7e-05 22.8 0.0 8.9e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ83433.1 - 0.00014 22.0 0.1 0.00032 20.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CDJ83433.1 - 0.0053 15.5 0.0 2.8 6.5 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 CDJ83433.1 - 0.066 13.8 1.6 5.1 7.7 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CDJ83433.1 - 0.21 10.9 0.0 0.38 10.0 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FMO-like PF00743.19 CDJ83434.1 - 2e-155 518.2 0.4 2.5e-155 517.9 0.4 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CDJ83434.1 - 2.3e-22 79.7 0.0 2.9e-19 69.5 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CDJ83434.1 - 8e-14 51.5 0.0 1.8e-11 43.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CDJ83434.1 - 2.7e-09 36.6 0.3 6e-08 32.2 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 CDJ83434.1 - 2.2e-07 31.0 0.0 0.00014 21.8 0.0 3.4 2 2 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 CDJ83434.1 - 1.2e-06 28.4 0.0 0.0007 19.3 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDJ83434.1 - 1.3e-05 25.3 0.0 3.2e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 CDJ83434.1 - 0.00037 19.9 0.0 0.00085 18.7 0.0 1.6 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 CDJ83434.1 - 0.0013 19.2 0.3 0.43 11.2 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ83434.1 - 0.003 16.3 0.0 0.68 8.6 0.1 2.4 3 0 0 3 3 3 2 HI0933-like protein AlaDh_PNT_C PF01262.21 CDJ83434.1 - 0.034 13.4 0.1 0.063 12.6 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 CDJ83434.1 - 0.041 13.0 0.0 0.092 11.8 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 CDJ83434.1 - 0.068 12.5 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 CDJ83434.1 - 0.14 11.7 0.1 0.29 10.7 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Granulin PF00396.18 CDJ83435.1 - 5e-11 42.7 26.3 8.5e-11 42.0 19.9 2.1 2 0 0 2 2 2 2 Granulin PI-PLC-X PF00388.19 CDJ83436.1 - 1.7e-59 199.6 0.0 7e-59 197.6 0.0 2.1 3 0 0 3 3 3 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CDJ83436.1 - 5.8e-40 136.2 0.1 5.8e-40 136.2 0.1 2.4 3 0 0 3 3 3 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_14 PF17787.1 CDJ83436.1 - 1.6e-25 89.5 1.6 1.8e-25 89.3 0.0 2.0 2 0 0 2 2 2 1 PH domain DUF1154 PF06631.11 CDJ83436.1 - 1.8e-14 53.5 11.9 1.8e-14 53.5 11.9 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1154) EF-hand_like PF09279.11 CDJ83436.1 - 3.1e-10 40.4 0.1 3.1e-10 40.4 0.1 3.7 5 0 0 5 5 5 1 Phosphoinositide-specific phospholipase C, efhand-like PLC-beta_C PF08703.10 CDJ83436.1 - 0.0012 18.9 34.1 0.0012 18.9 34.1 2.3 2 0 0 2 2 2 1 PLC-beta C terminal ACI44 PF15270.6 CDJ83437.1 - 5e-07 29.8 0.0 8.3 6.7 0.0 5.3 3 1 2 5 5 5 4 Metallo-carboxypeptidase inhibitor Fibrinogen_BP PF08017.11 CDJ83437.1 - 0.0031 16.0 0.0 0.0047 15.4 0.0 1.2 1 0 0 1 1 1 1 Fibrinogen binding protein Arm-DNA-bind_3 PF13356.6 CDJ83437.1 - 0.0041 17.5 0.5 96 3.5 0.0 5.8 4 2 1 5 5 5 0 Arm DNA-binding domain Pheromone PF08015.11 CDJ83437.1 - 0.029 15.4 12.1 0.15 13.1 0.2 3.9 2 1 1 3 3 3 0 Fungal mating-type pheromone Branch PF02485.21 CDJ83438.1 - 9.9e-20 71.1 0.1 2.1e-19 70.0 0.1 1.5 1 1 0 1 1 1 1 Core-2/I-Branching enzyme TMEM18 PF14770.6 CDJ83439.1 - 0.012 15.6 0.1 0.025 14.6 0.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 18 RIH_assoc PF08454.11 CDJ83440.1 - 2.1e-31 107.8 2.8 2.6e-31 107.5 0.1 2.7 3 0 0 3 3 3 1 RyR and IP3R Homology associated RR_TM4-6 PF06459.12 CDJ83440.1 - 4.1e-18 66.2 0.2 1.3e-17 64.5 0.2 1.9 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Ion_trans PF00520.31 CDJ83440.1 - 2.5e-16 59.7 4.3 2.8e-15 56.2 3.7 2.8 2 1 1 3 3 3 1 Ion transport protein EF-hand_7 PF13499.6 CDJ83440.1 - 1.7e-09 38.0 0.5 1.7e-09 38.0 0.5 2.9 4 0 0 4 4 3 1 EF-hand domain pair EF-hand_5 PF13202.6 CDJ83440.1 - 1e-08 34.3 0.1 0.00019 20.8 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 CDJ83440.1 - 2e-08 33.2 0.3 0.0011 18.4 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDJ83440.1 - 1.8e-07 30.9 0.3 6.3e-07 29.1 0.3 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ83440.1 - 3.2e-06 26.6 2.6 0.00025 20.7 0.0 3.1 3 0 0 3 3 2 1 EF-hand domain RRS1 PF04939.12 CDJ83440.1 - 0.011 15.6 0.0 0.086 12.7 0.0 2.4 2 0 0 2 2 2 0 Ribosome biogenesis regulatory protein (RRS1) GST_C_3 PF14497.6 CDJ83440.1 - 0.045 13.9 0.1 0.34 11.1 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain SPARC_Ca_bdg PF10591.9 CDJ83440.1 - 0.096 13.0 0.2 0.26 11.6 0.2 1.7 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CDJ83440.1 - 0.099 13.5 0.2 0.39 11.6 0.1 2.0 2 0 0 2 2 1 0 EF-hand domain RYDR_ITPR PF01365.21 CDJ83441.1 - 1.4e-104 347.9 0.6 1.6e-51 174.6 0.0 2.8 2 0 0 2 2 2 2 RIH domain SPRY PF00622.28 CDJ83441.1 - 2.1e-62 208.5 1.9 1.9e-19 69.9 0.0 3.7 3 0 0 3 3 3 3 SPRY domain RyR PF02026.16 CDJ83441.1 - 4e-59 196.8 0.7 3.3e-30 104.1 0.2 3.1 2 0 0 2 2 2 2 RyR domain MIR PF02815.19 CDJ83441.1 - 4.4e-53 179.9 0.7 1e-47 162.4 0.1 2.9 2 1 0 2 2 2 2 MIR domain Ins145_P3_rec PF08709.11 CDJ83441.1 - 8.4e-51 172.2 2.4 9.2e-50 168.8 0.2 3.4 3 1 1 4 4 4 1 Inositol 1,4,5-trisphosphate/ryanodine receptor Abhydro_lipase PF04083.16 CDJ83442.1 - 6.3e-25 86.5 0.0 1.2e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 CDJ83442.1 - 3.4e-15 56.4 1.5 7e-15 55.4 1.5 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ83442.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PAF-AH_p_II PF03403.13 CDJ83442.1 - 0.092 11.2 0.0 0.14 10.6 0.0 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Retrotrans_gag PF03732.17 CDJ83443.1 - 0.032 14.5 0.1 0.053 13.8 0.1 1.3 1 0 0 1 1 1 0 Retrotransposon gag protein RE_CfrBI PF09516.10 CDJ83443.1 - 0.15 11.4 0.1 0.24 10.8 0.1 1.2 1 0 0 1 1 1 0 CfrBI restriction endonuclease BAT2_N PF07001.11 CDJ83445.1 - 4.5e-12 46.8 0.2 5.2e-12 46.6 0.2 1.2 1 0 0 1 1 1 1 BAT2 N-terminus Cyclase_polyket PF04673.12 CDJ83446.1 - 0.018 15.3 0.5 0.025 14.8 0.5 1.1 1 0 0 1 1 1 0 Polyketide synthesis cyclase Peptidase_C13 PF01650.18 CDJ83447.1 - 9.1e-69 231.8 0.5 1.1e-68 231.5 0.5 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 CDJ83447.1 - 0.0013 18.7 0.0 0.0019 18.2 0.0 1.2 1 0 0 1 1 1 1 Caspase domain DUF2675 PF11247.8 CDJ83447.1 - 0.041 14.0 0.0 0.075 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2675) Aa_trans PF01490.18 CDJ83448.1 - 2.9e-30 105.3 25.5 1.2e-15 57.2 11.0 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein TBCC PF07986.12 CDJ83449.1 - 0.054 13.2 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Tubulin binding cofactor C NUDIX PF00293.28 CDJ83450.1 - 4.9e-14 52.5 0.0 7e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 CDJ83450.1 - 3.4e-05 23.4 4.3 5.6e-05 22.7 4.3 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain IBR PF01485.21 CDJ83450.1 - 0.026 14.7 0.3 0.049 13.9 0.3 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DZR PF12773.7 CDJ83450.1 - 0.033 14.2 0.6 0.072 13.1 0.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon VP_N-CPKC PF11475.8 CDJ83450.1 - 0.12 12.3 1.1 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 Virion protein N terminal domain zf_C2H2_13 PF18508.1 CDJ83450.1 - 0.12 12.0 0.2 0.24 11.0 0.2 1.5 1 0 0 1 1 1 0 Zinc finger domain Nudix_N_2 PF14803.6 CDJ83450.1 - 0.12 12.3 2.1 0.42 10.6 2.1 1.9 1 1 0 1 1 1 0 Nudix N-terminal zinc_ribbon_2 PF13240.6 CDJ83450.1 - 0.14 11.9 2.0 0.26 11.1 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Auto_anti-p27 PF06677.12 CDJ83450.1 - 0.18 12.0 0.9 0.38 11.0 0.9 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-ribbon_3 PF13248.6 CDJ83450.1 - 0.26 10.7 5.8 2.2 7.8 5.8 2.3 1 1 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 CDJ83450.1 - 0.35 11.0 3.4 1.7 8.8 0.1 2.4 1 1 1 2 2 2 0 Zinc ribbon domain zf-C4_Topoisom PF01396.19 CDJ83450.1 - 0.63 9.9 5.3 2.9 7.7 5.3 2.0 1 1 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger DUF35_N PF12172.8 CDJ83450.1 - 1 9.3 6.3 7.4 6.6 0.4 2.4 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) TUDOR PF00567.24 CDJ83451.1 - 0.00055 20.0 0.1 0.00074 19.5 0.1 1.2 1 0 0 1 1 1 1 Tudor domain DUF3361 PF11841.8 CDJ83453.1 - 0.014 15.3 2.0 0.086 12.8 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) RUN PF02759.19 CDJ83453.1 - 0.018 15.0 0.2 0.071 13.1 0.1 2.0 2 0 0 2 2 2 0 RUN domain CTP_synth_N PF06418.14 CDJ83454.1 - 8.7e-116 385.9 0.0 1.2e-115 385.4 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 CDJ83454.1 - 2.5e-44 151.3 0.1 1e-35 123.3 0.0 2.4 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CDJ83454.1 - 4.8e-05 23.2 0.7 0.027 14.2 0.2 3.1 2 1 0 3 3 3 2 Peptidase C26 CbiA PF01656.23 CDJ83454.1 - 0.00068 19.7 0.0 0.0026 17.8 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 CDJ83454.1 - 0.018 14.3 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase MeaB PF03308.16 CDJ83454.1 - 0.073 12.0 0.1 0.15 11.0 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DJ-1_PfpI PF01965.24 CDJ83454.1 - 0.095 12.5 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family TIP120 PF08623.10 CDJ83455.1 - 6.5e-61 205.0 3.5 6.5e-61 205.0 3.5 4.2 6 0 0 6 6 6 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 CDJ83455.1 - 5.1e-17 62.0 32.0 0.0072 16.7 0.2 9.7 8 3 2 10 10 10 6 HEAT repeats HEAT_EZ PF13513.6 CDJ83455.1 - 6.8e-13 48.8 19.5 0.01 16.3 0.0 11.4 10 3 3 13 13 13 4 HEAT-like repeat HEAT PF02985.22 CDJ83455.1 - 1.2e-11 43.8 18.5 0.28 11.6 0.0 11.6 12 0 0 12 12 12 4 HEAT repeat DUF3385 PF11865.8 CDJ83455.1 - 2.3e-08 34.1 3.4 1.1e-05 25.4 0.1 5.4 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) Cnd1 PF12717.7 CDJ83455.1 - 4.8e-08 33.2 19.9 0.011 15.8 0.2 6.2 4 2 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CDJ83455.1 - 1.2e-06 27.4 19.6 0.018 13.6 1.4 5.9 3 2 3 6 6 6 3 Adaptin N terminal region Arm PF00514.23 CDJ83455.1 - 4.8e-05 23.2 1.5 4.2 7.5 0.0 5.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 CDJ83455.1 - 0.001 19.3 2.3 16 5.7 0.0 5.9 6 2 0 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 CDJ83455.1 - 0.002 18.7 3.2 65 4.2 0.0 6.1 5 1 0 5 5 5 0 Vacuolar 14 Fab1-binding region UME PF08064.13 CDJ83455.1 - 0.0035 17.2 8.6 11 6.0 0.0 7.3 8 2 0 8 8 8 1 UME (NUC010) domain BLM10_mid PF16507.5 CDJ83455.1 - 0.044 12.4 0.6 0.19 10.3 0.0 2.4 3 0 0 3 3 3 0 Proteasome-substrate-size regulator, mid region RasGEF_N_2 PF14663.6 CDJ83455.1 - 0.065 13.6 1.2 3 8.3 0.1 3.7 3 0 0 3 3 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Syntaxin_2 PF14523.6 CDJ83455.1 - 0.2 12.1 1.1 5.6 7.4 0.0 2.8 2 0 0 2 2 2 0 Syntaxin-like protein ParcG PF10274.9 CDJ83455.1 - 0.92 9.6 11.8 0.63 10.1 0.2 5.2 6 1 1 7 7 7 0 Parkin co-regulated protein Hydrolase_4 PF12146.8 CDJ83456.1 - 1.5e-18 66.9 0.0 1.5e-13 50.6 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ83456.1 - 1.8e-13 50.7 0.1 1.3e-08 34.8 0.1 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ83456.1 - 1.6e-11 45.3 0.0 2.8e-11 44.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CDJ83456.1 - 0.00011 22.1 0.0 0.00021 21.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold LIP PF03583.14 CDJ83456.1 - 0.00079 18.8 0.1 0.26 10.5 0.0 2.1 2 0 0 2 2 2 2 Secretory lipase Say1_Mug180 PF10340.9 CDJ83456.1 - 0.0011 18.0 0.0 0.0017 17.3 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 CDJ83456.1 - 0.0024 17.7 0.0 0.41 10.4 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.18 CDJ83456.1 - 0.0039 16.8 0.0 0.02 14.4 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family LIDHydrolase PF10230.9 CDJ83456.1 - 0.0053 16.4 2.6 0.37 10.3 0.1 2.9 2 1 1 3 3 3 1 Lipid-droplet associated hydrolase COesterase PF00135.28 CDJ83456.1 - 0.014 14.3 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family DUF818 PF05677.12 CDJ83456.1 - 0.017 14.1 0.0 0.38 9.6 0.0 2.0 2 0 0 2 2 2 0 Chlamydia CHLPS protein (DUF818) DUF900 PF05990.12 CDJ83456.1 - 0.12 11.8 0.1 0.2 11.1 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 CDJ83456.1 - 0.23 11.2 0.6 0.49 10.1 0.6 1.7 1 1 0 1 1 1 0 PGAP1-like protein DUF1295 PF06966.12 CDJ83457.1 - 0.081 12.4 2.3 0.075 12.5 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) UL2 PF08196.11 CDJ83457.1 - 8.6 6.4 6.5 2.8 8.0 0.2 3.1 3 0 0 3 3 3 0 UL2 protein PRIMA1 PF16101.5 CDJ83458.1 - 2.2 8.3 6.1 0.17 11.9 0.2 1.8 1 1 1 2 2 2 0 Proline-rich membrane anchor 1 BAR_3_WASP_bdg PF10456.9 CDJ83459.1 - 1.3e-78 263.7 7.0 1.6e-78 263.4 6.3 1.4 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein PX PF00787.24 CDJ83459.1 - 4.4e-21 75.0 1.7 5.7e-21 74.6 0.2 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 CDJ83459.1 - 0.001 18.7 2.5 0.19 11.2 0.3 2.7 1 1 1 2 2 2 2 Vps5 C terminal like DUF3896 PF13035.6 CDJ83459.1 - 0.038 14.1 0.5 0.11 12.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) TolA_bind_tri PF16331.5 CDJ83459.1 - 0.1 12.7 1.9 0.4 10.8 0.1 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation Nudc_N PF14050.6 CDJ83459.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 N-terminal conserved domain of Nudc. BAR_3 PF16746.5 CDJ83459.1 - 0.11 12.1 5.7 0.44 10.2 5.7 2.0 1 1 0 1 1 1 0 BAR domain of APPL family DUF1057 PF06342.12 CDJ83460.1 - 7.8e-78 261.5 0.0 8.8e-78 261.3 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Hydrolase_4 PF12146.8 CDJ83460.1 - 1e-10 41.3 0.0 1.9e-10 40.4 0.0 1.6 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ83460.1 - 1.2e-10 41.5 0.0 2.3e-10 40.6 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ83460.1 - 3.2e-06 27.9 0.0 4.2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 CDJ83460.1 - 0.0013 17.7 0.0 0.0024 16.8 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 CDJ83460.1 - 0.012 14.6 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_5 PF12695.7 CDJ83460.1 - 0.067 13.0 0.1 0.68 9.7 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF1749 PF08538.10 CDJ83460.1 - 0.17 11.0 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) ACDC PF14733.6 CDJ83460.1 - 0.18 12.1 0.0 0.44 10.9 0.0 1.7 1 0 0 1 1 1 0 AP2-coincident C-terminal LIDHydrolase PF10230.9 CDJ83460.1 - 0.19 11.3 0.0 0.42 10.1 0.0 1.6 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase DUF1057 PF06342.12 CDJ83461.1 - 1e-69 234.9 0.0 1.2e-69 234.6 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Hydrolase_4 PF12146.8 CDJ83461.1 - 1.7e-10 40.6 0.0 4e-10 39.4 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ83461.1 - 7.6e-10 38.9 0.1 1.7e-09 37.7 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ83461.1 - 5e-08 33.8 0.0 5.6e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 CDJ83461.1 - 0.013 14.4 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 CDJ83461.1 - 0.04 12.9 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Thioesterase PF00975.20 CDJ83461.1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 CDJ83461.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Got1 PF04178.12 CDJ83462.1 - 3.9e-15 56.3 7.9 6.1e-15 55.6 7.9 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family AgrB PF04647.15 CDJ83462.1 - 0.068 12.5 4.8 0.092 12.0 4.8 1.2 1 0 0 1 1 1 0 Accessory gene regulator B DFRP_C PF16543.5 CDJ83463.1 - 5.4e-22 78.1 7.5 5.4e-22 78.1 7.5 3.8 4 1 0 4 4 4 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 CDJ83463.1 - 1.6e-07 32.0 23.9 6.8e-05 23.5 10.2 4.3 2 1 1 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 CDJ83463.1 - 2.6e-05 24.1 19.6 3.3e-05 23.8 7.8 3.3 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 CDJ83463.1 - 3e-05 23.7 12.0 0.00015 21.5 2.2 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH PF00642.24 CDJ83463.1 - 0.00016 21.5 1.7 0.00016 21.5 1.7 3.0 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CVNH PF08881.10 CDJ83463.1 - 0.051 14.3 2.8 1.3 9.7 0.9 2.5 2 0 0 2 2 2 0 CVNH domain Phage_B PF02304.15 CDJ83463.1 - 0.2 12.0 6.0 4.5 7.7 1.2 2.6 2 0 0 2 2 2 0 Scaffold protein B zf-CCCH_2 PF14608.6 CDJ83463.1 - 0.9 10.1 13.3 0.93 10.1 6.2 2.8 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CDJ83463.1 - 7.6 6.8 14.5 0.78 10.0 1.5 3.1 2 1 2 4 4 4 0 Zinc-finger containing family Transket_pyr PF02779.24 CDJ83464.1 - 5.3e-41 140.3 0.0 7.2e-41 139.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CDJ83464.1 - 3.8e-36 123.7 0.1 7.3e-36 122.8 0.0 1.5 2 0 0 2 2 2 1 Transketolase, C-terminal domain Ion_trans_2 PF07885.16 CDJ83465.1 - 2.1e-30 104.5 21.1 6.7e-19 67.6 4.9 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 CDJ83465.1 - 0.00081 18.7 12.2 0.0092 15.2 0.9 2.3 2 0 0 2 2 2 2 Ion transport protein IRK PF01007.20 CDJ83465.1 - 0.097 12.5 2.7 0.53 10.1 0.2 2.5 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain VWA_2 PF13519.6 CDJ83466.1 - 2.7e-08 34.4 0.0 7.5e-08 33.0 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain INT_SG_DDX_CT_C PF15300.6 CDJ83466.1 - 0.0037 17.0 0.0 0.0093 15.7 0.0 1.7 1 0 0 1 1 1 1 INTS6/SAGE1/DDX26B/CT45 C-terminus adh_short PF00106.25 CDJ83467.1 - 5.5e-23 81.4 0.0 1.3e-19 70.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ83467.1 - 1.7e-11 44.1 0.5 1.2e-10 41.4 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CDJ83467.1 - 2.2e-09 37.1 0.0 3.1e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 CDJ83467.1 - 1.4e-08 34.9 0.1 3.1e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CDJ83467.1 - 2.8e-07 30.6 0.0 4.4e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CDJ83467.1 - 9.9e-05 21.9 0.0 0.00015 21.3 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 CDJ83467.1 - 0.00087 18.9 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 CDJ83467.1 - 0.0023 17.1 0.0 0.28 10.3 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein F420_oxidored PF03807.17 CDJ83467.1 - 0.0052 17.3 0.1 0.13 12.8 0.0 2.9 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.8 CDJ83467.1 - 0.051 13.3 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.17 CDJ83467.1 - 0.06 12.4 0.0 0.091 11.8 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_hydro_31 PF01055.26 CDJ83467.1 - 0.061 12.5 0.0 0.075 12.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 Shikimate_DH PF01488.20 CDJ83467.1 - 0.095 12.8 0.1 0.7 10.0 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.19 CDJ83467.1 - 0.14 11.2 0.4 0.18 10.7 0.4 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CDJ83467.1 - 0.14 11.2 0.2 0.22 10.6 0.2 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein E3_UFM1_ligase PF09743.9 CDJ83468.1 - 1.1e-77 261.3 0.3 6.9e-77 258.7 0.0 2.1 2 0 0 2 2 2 1 E3 UFM1-protein ligase 1 FeoC PF09012.10 CDJ83468.1 - 0.21 11.7 0.7 4.3 7.5 0.1 3.0 3 0 0 3 3 3 0 FeoC like transcriptional regulator FCD PF07729.12 CDJ83468.1 - 1.5 9.2 6.7 4.2 7.8 0.3 4.0 4 0 0 4 4 4 0 FCD domain COG2 PF06148.11 CDJ83469.1 - 4.4e-32 110.9 1.6 1.3e-31 109.4 1.6 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 CDJ83469.1 - 5.3e-21 75.3 0.3 4.2e-19 69.2 0.0 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF3510) Vps51 PF08700.11 CDJ83469.1 - 2e-07 31.0 0.6 6.7e-07 29.3 0.1 2.2 2 0 0 2 2 2 1 Vps51/Vps67 DUF2451 PF10474.9 CDJ83469.1 - 0.0021 17.9 0.2 0.039 13.8 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function C-terminus (DUF2451) LPP PF04728.13 CDJ83469.1 - 0.05 14.0 0.0 0.15 12.4 0.0 1.9 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Adaptin_N PF01602.20 CDJ83470.1 - 0.023 13.3 0.1 0.028 13.0 0.1 1.1 1 0 0 1 1 1 0 Adaptin N terminal region HEAT PF02985.22 CDJ83470.1 - 0.06 13.6 0.1 0.31 11.4 0.0 2.2 2 0 0 2 2 2 0 HEAT repeat Metallophos PF00149.28 CDJ83471.1 - 4.8e-32 112.1 0.1 6.4e-32 111.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDJ83471.1 - 0.0023 18.1 0.0 0.0035 17.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 CDJ83471.1 - 0.017 15.6 0.2 0.028 14.8 0.2 1.4 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain EGF_CA PF07645.15 CDJ83472.1 - 0.003 17.7 2.6 0.003 17.7 2.6 2.9 3 1 1 4 4 4 1 Calcium-binding EGF domain EGF PF00008.27 CDJ83472.1 - 0.062 13.6 3.0 0.062 13.6 3.0 3.6 3 1 0 3 3 3 0 EGF-like domain EGF_3 PF12947.7 CDJ83472.1 - 0.54 10.5 9.3 0.21 11.8 1.9 2.8 2 1 0 2 2 2 0 EGF domain zf-MIZ PF02891.20 CDJ83474.1 - 1.3e-20 72.9 6.8 3.4e-20 71.5 6.8 1.8 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger PINIT PF14324.6 CDJ83474.1 - 7.1e-14 52.4 0.5 1.2e-13 51.6 0.5 1.3 1 0 0 1 1 1 1 PINIT domain zf-Nse PF11789.8 CDJ83474.1 - 8.5e-06 25.5 4.3 1.8e-05 24.4 4.3 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 CDJ83474.1 - 0.032 14.1 2.7 0.083 12.8 2.7 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 CDJ83474.1 - 1.6 9.1 6.9 3.6 8.0 6.9 1.6 1 0 0 1 1 1 0 Ring finger domain SRF-TF PF00319.18 CDJ83475.1 - 4.4e-25 86.9 0.4 6.7e-25 86.3 0.4 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) GHD PF17834.1 CDJ83475.1 - 0.024 14.7 0.1 0.053 13.6 0.1 1.5 1 0 0 1 1 1 0 Beta-sandwich domain in beta galactosidase YABBY PF04690.13 CDJ83475.1 - 0.41 11.2 3.1 0.51 10.9 2.0 1.7 2 0 0 2 2 2 0 YABBY protein TFIIA PF03153.13 CDJ83475.1 - 0.74 9.7 17.9 0.95 9.4 17.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ83475.1 - 1.3 8.5 15.1 0.48 10.0 12.1 1.8 2 0 0 2 2 2 0 Spt20 family DUF5302 PF17227.2 CDJ83475.1 - 4.1 8.5 0.0 4.1 8.5 0.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5302) CAF1A PF12253.8 CDJ83476.1 - 1.8e-23 82.5 8.0 1.8e-23 82.5 8.0 6.0 3 2 2 5 5 5 1 Chromatin assembly factor 1 subunit A Hamartin PF04388.12 CDJ83476.1 - 0.27 9.9 18.5 0.37 9.4 18.5 1.3 1 0 0 1 1 1 0 Hamartin protein GYF PF02213.16 CDJ83477.1 - 3.5e-15 55.4 0.6 5.9e-15 54.7 0.6 1.4 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 CDJ83477.1 - 0.0022 17.8 0.5 0.0037 17.0 0.5 1.3 1 0 0 1 1 1 1 GYF domain 2 DUF2052 PF09747.9 CDJ83478.1 - 1.6e-35 123.1 22.3 2.7e-35 122.3 22.3 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Pertussis_S2S3 PF02918.15 CDJ83478.1 - 0.14 12.0 0.1 0.31 11.0 0.0 1.6 2 0 0 2 2 2 0 Pertussis toxin, subunit 2 and 3, C-terminal domain Peptidase_C1 PF00112.23 CDJ83480.1 - 3.1e-69 233.4 2.6 4.1e-69 233.0 2.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 CDJ83480.1 - 7e-05 22.6 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 CDJ83480.1 - 0.0096 14.7 2.3 0.27 9.9 0.4 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Lipase_2 PF01674.18 CDJ83481.1 - 2.1e-76 256.3 0.0 2.7e-76 255.9 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 2) Abhydrolase_6 PF12697.7 CDJ83481.1 - 0.0011 19.6 0.1 0.0017 19.0 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S28 PF05577.12 CDJ83481.1 - 0.03 13.1 0.3 0.042 12.7 0.3 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 LCAT PF02450.15 CDJ83481.1 - 0.045 12.9 0.0 0.34 10.0 0.0 2.3 3 0 0 3 3 3 0 Lecithin:cholesterol acyltransferase ShK PF01549.24 CDJ83482.1 - 1.2e-06 29.0 7.3 2e-06 28.2 7.3 1.4 1 0 0 1 1 1 1 ShK domain-like Trypan_PARP PF05887.11 CDJ83482.1 - 0.07 13.1 3.3 0.11 12.5 3.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Aminotran_1_2 PF00155.21 CDJ83483.1 - 4.7e-55 187.2 0.0 5.7e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CDJ83483.1 - 0.0079 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 CDJ83483.1 - 0.0094 14.9 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V CwfJ_C_1 PF04677.15 CDJ83483.1 - 0.26 11.1 1.6 2.3 8.1 0.0 2.9 4 0 0 4 4 4 0 Protein similar to CwfJ C-terminus 1 DSL PF01414.19 CDJ83484.1 - 7.3e-13 48.6 6.5 7.3e-13 48.6 6.5 4.2 3 1 1 4 4 4 1 Delta serrate ligand EGF PF00008.27 CDJ83484.1 - 1.1e-10 41.6 71.1 5.9e-06 26.5 9.5 6.1 4 1 1 5 5 5 4 EGF-like domain EGF_2 PF07974.13 CDJ83484.1 - 1.5e-08 34.9 87.0 0.034 14.5 12.0 7.1 5 2 1 6 6 6 4 EGF-like domain hEGF PF12661.7 CDJ83484.1 - 0.00035 21.1 62.9 0.0011 19.5 7.9 7.3 7 1 1 8 8 8 3 Human growth factor-like EGF C_tripleX PF02363.19 CDJ83484.1 - 0.022 15.0 1.9 0.022 15.0 1.9 4.8 4 0 0 4 4 4 0 Cysteine rich repeat Laminin_EGF PF00053.24 CDJ83484.1 - 0.73 10.0 70.4 0.61 10.3 14.9 6.3 1 1 5 6 6 6 0 Laminin EGF domain zf-RING_UBOX PF13445.6 CDJ83485.1 - 1.1e-06 28.5 3.2 1.1e-06 28.5 3.2 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 CDJ83485.1 - 2.2e-06 27.9 7.5 2.2e-06 27.9 7.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 CDJ83485.1 - 7.6e-05 22.6 5.8 7.6e-05 22.6 5.8 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CDJ83485.1 - 0.00054 19.8 6.2 0.00054 19.8 6.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ83485.1 - 0.00081 19.5 7.7 0.00081 19.5 7.7 2.2 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 CDJ83485.1 - 0.0024 17.8 4.3 0.0044 17.0 3.4 2.0 1 1 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_2 PF13923.6 CDJ83485.1 - 0.0025 17.6 2.4 0.0025 17.6 2.4 2.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CDJ83485.1 - 0.27 11.4 4.3 0.82 9.9 4.3 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-U1 PF06220.12 CDJ83485.1 - 0.27 11.0 3.4 0.61 9.9 3.4 1.6 1 0 0 1 1 1 0 U1 zinc finger Prok-RING_4 PF14447.6 CDJ83485.1 - 0.34 10.8 12.3 0.14 12.0 7.5 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 CDJ83485.1 - 3.6 7.8 7.4 0.17 12.1 1.4 1.9 2 0 0 2 2 2 0 FANCL C-terminal domain Peptidase_A22B PF04258.13 CDJ83486.1 - 1.4e-62 211.8 19.6 2e-62 211.3 19.6 1.2 1 0 0 1 1 1 1 Signal peptide peptidase DUF5113 PF17140.4 CDJ83486.1 - 0.066 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) zf-Tim10_DDP PF02953.15 CDJ83487.1 - 2.4e-24 84.7 4.3 3.4e-24 84.3 4.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Gp-FAR-1 PF05823.12 CDJ83487.1 - 0.032 14.6 0.5 0.057 13.8 0.4 1.4 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) CARD_2 PF16739.5 CDJ83487.1 - 0.035 14.1 0.8 0.07 13.1 0.5 1.6 1 1 1 2 2 2 0 Caspase recruitment domain Mt_ATP-synt_B PF05405.14 CDJ83487.1 - 0.13 11.9 3.1 0.17 11.5 3.1 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF3621 PF12285.8 CDJ83487.1 - 0.13 12.7 6.0 0.15 12.4 4.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3621) DUF2605 PF10792.9 CDJ83487.1 - 0.84 9.6 4.0 0.44 10.5 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) Rad60-SLD PF11976.8 CDJ83489.1 - 3.2e-18 65.3 0.1 4.8e-18 64.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CDJ83489.1 - 3.1e-14 52.5 0.1 4.2e-14 52.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Peptidase_M24 PF00557.24 CDJ83490.1 - 9.6e-113 375.0 0.2 2.7e-55 187.3 0.1 2.6 3 0 0 3 3 3 2 Metallopeptidase family M24 AMP_N PF05195.16 CDJ83490.1 - 2.9e-44 149.7 0.3 1.7e-24 85.9 0.0 3.0 2 0 0 2 2 2 2 Aminopeptidase P, N-terminal domain DUF2100 PF09873.9 CDJ83490.1 - 0.0074 16.2 0.1 5.2 6.9 0.1 2.5 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2100) DUF3006 PF11213.8 CDJ83490.1 - 0.025 14.8 1.0 20 5.5 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3006) DUF269 PF03270.13 CDJ83490.1 - 0.071 13.2 0.0 8.6 6.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF269 3HCDH PF00725.22 CDJ83490.1 - 0.13 12.9 0.4 4.7 7.9 0.0 2.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF5616 PF18481.1 CDJ83490.1 - 0.17 12.2 0.1 2.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5616) Peptidase_M24 PF00557.24 CDJ83491.1 - 1.9e-33 115.9 0.0 4.5e-33 114.7 0.0 1.6 1 1 0 1 1 1 1 Metallopeptidase family M24 3HCDH PF00725.22 CDJ83491.1 - 0.014 16.0 0.0 0.024 15.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Peptidase_M24 PF00557.24 CDJ83492.1 - 3.1e-59 200.2 0.1 1.9e-58 197.6 0.1 1.9 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.16 CDJ83492.1 - 3.3e-24 85.0 0.0 6.8e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Collagen PF01391.18 CDJ83492.1 - 2.3e-22 78.5 88.6 1.3e-09 37.7 34.6 4.5 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Collagen PF01391.18 CDJ83493.1 - 3.2e-22 78.1 105.5 4.8e-06 26.2 13.5 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ83493.1 - 2.7e-07 30.5 0.1 3.9e-07 30.0 0.1 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain DUF4706 PF15797.5 CDJ83493.1 - 0.13 12.9 0.0 0.19 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4706) Col_cuticle_N PF01484.17 CDJ83494.1 - 7.9e-08 32.3 0.5 9.4e-08 32.0 0.5 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ83494.1 - 0.024 14.4 2.6 0.033 13.9 2.6 1.2 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) ECSCR PF15820.5 CDJ83495.1 - 0.032 14.1 0.3 0.08 12.8 0.3 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator VID27_PH PF17747.1 CDJ83495.1 - 0.93 9.8 6.0 3.8 7.8 0.0 3.9 4 0 0 4 4 4 0 VID27 PH-like domain DUF5620 PF18522.1 CDJ83495.1 - 3.9 7.9 6.4 4.3 7.8 0.8 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF5620) Asp PF00026.23 CDJ83497.1 - 2.2e-75 254.0 0.5 2.5e-38 132.3 0.1 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ83497.1 - 4.5e-11 43.3 7.7 9.4e-11 42.3 3.9 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ83497.1 - 0.00014 21.7 0.0 0.00095 19.0 0.0 2.2 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CDJ83497.1 - 0.0033 18.0 0.1 1.1 10.0 0.0 3.2 3 0 0 3 3 3 1 Aspartyl protease HU-CCDC81_bac_2 PF18175.1 CDJ83498.1 - 0.061 13.2 0.1 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 DUF4743 PF15916.5 CDJ83498.1 - 0.066 13.2 0.2 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4743) adh_short PF00106.25 CDJ83499.1 - 4.4e-29 101.3 0.0 5.8e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ83499.1 - 1.5e-22 80.4 0.0 2e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ83499.1 - 1.7e-07 31.3 0.0 2.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 KR domain RVT_1 PF00078.27 CDJ83500.1 - 1.4e-21 77.0 0.0 2.1e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CDJ83501.1 - 2.6e-14 53.3 0.0 4.6e-14 52.5 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hemolysin_N PF12563.8 CDJ83501.1 - 0.053 13.1 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Hemolytic toxin N terminal RVT_1 PF00078.27 CDJ83503.1 - 2.5e-22 79.5 0.0 5.1e-22 78.5 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CDJ83504.1 - 0.0021 17.6 0.0 0.0033 17.0 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CDJ83504.1 - 0.0053 16.6 0.0 0.0093 15.8 0.0 1.5 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Xpo1 PF08389.12 CDJ83507.1 - 5.6e-14 52.5 1.1 2.3e-09 37.5 0.6 3.9 3 0 0 3 3 3 2 Exportin 1-like protein RTP1_C1 PF10363.9 CDJ83507.1 - 1.6e-12 47.6 1.5 6.4e-09 36.0 0.0 5.1 4 2 1 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 CDJ83507.1 - 2.7e-07 29.5 7.4 0.0079 14.8 1.8 4.9 5 0 0 5 5 5 3 Adaptin N terminal region HEAT_2 PF13646.6 CDJ83507.1 - 5.5e-06 26.7 8.0 0.075 13.4 0.4 6.0 5 2 2 7 7 7 4 HEAT repeats Cnd1 PF12717.7 CDJ83507.1 - 1.6e-05 25.0 0.3 0.099 12.7 0.0 3.9 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CDJ83507.1 - 0.00014 22.3 0.4 0.0057 17.2 0.0 3.7 4 0 0 4 4 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CDJ83507.1 - 0.00015 21.7 8.0 0.26 11.6 0.1 6.1 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 CDJ83507.1 - 0.00021 21.7 4.8 0.0055 17.2 0.1 5.0 5 0 0 5 5 5 1 HEAT-like repeat RTP1_C2 PF10304.9 CDJ83507.1 - 0.0077 15.9 1.0 0.023 14.4 1.0 1.9 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 RasGEF_N_2 PF14663.6 CDJ83507.1 - 0.013 15.8 0.2 0.38 11.2 0.0 3.5 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain MULE PF10551.9 CDJ83507.1 - 0.031 14.7 0.1 6.2 7.3 0.0 3.2 3 0 0 3 3 3 0 MULE transposase domain DUF3384 PF11864.8 CDJ83507.1 - 0.048 12.6 6.7 0.029 13.3 0.3 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF3384) Transmemb_17 PF09799.9 CDJ83508.1 - 1.1e-16 61.4 13.0 1.2e-16 61.2 10.5 2.0 1 1 1 2 2 2 2 Predicted membrane protein zf-C2H2 PF00096.26 CDJ83509.1 - 0.0035 17.7 25.4 0.0098 16.3 5.8 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.7 CDJ83509.1 - 0.017 15.5 13.3 2.2 8.8 1.3 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CDJ83509.1 - 0.33 11.9 31.0 0.35 11.8 5.4 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger AKAP95 PF04988.12 CDJ83509.1 - 0.65 10.2 3.5 3.6 7.8 0.5 2.3 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Sugar_tr PF00083.24 CDJ83510.1 - 1.6e-32 113.0 18.5 2.3e-32 112.5 18.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ83510.1 - 1.9e-23 82.9 24.4 6.1e-17 61.6 20.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2208 PF09973.9 CDJ83510.1 - 0.27 10.8 4.3 0.74 9.4 0.8 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) CitMHS PF03600.16 CDJ83510.1 - 2.3 7.4 15.4 18 4.4 15.0 2.2 1 1 0 1 1 1 0 Citrate transporter Exo_endo_phos_2 PF14529.6 CDJ83512.1 - 0.018 14.9 0.0 0.028 14.3 0.0 1.4 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase HTH_3 PF01381.22 CDJ83515.1 - 2.4e-14 53.1 0.0 4.8e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 CDJ83515.1 - 1.3e-10 41.5 0.0 1.9e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 CDJ83515.1 - 5.3e-09 36.0 0.0 8.9e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 CDJ83515.1 - 0.0066 16.9 0.1 0.015 15.8 0.1 1.6 1 1 1 2 2 2 1 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.6 CDJ83515.1 - 0.014 15.3 0.1 0.046 13.7 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 CDJ83515.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT LBP_BPI_CETP PF01273.25 CDJ83516.1 - 1.6e-18 66.9 0.4 3.1e-18 65.9 0.4 1.5 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP_C PF02886.17 CDJ83516.1 - 4.8e-11 42.6 0.1 1.5e-09 37.7 0.0 2.6 2 1 0 2 2 2 1 LBP / BPI / CETP family, C-terminal domain Cpn60_TCP1 PF00118.24 CDJ83516.1 - 0.079 11.6 0.5 0.35 9.4 0.2 1.9 2 0 0 2 2 2 0 TCP-1/cpn60 chaperonin family UCR_hinge PF02320.16 CDJ83519.1 - 3.3e-17 62.4 4.6 3.7e-17 62.3 4.6 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein SPX PF03105.19 CDJ83523.1 - 0.12 12.2 1.1 0.21 11.5 0.9 1.4 1 1 0 1 1 1 0 SPX domain IBN_N PF03810.19 CDJ83525.1 - 0.082 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Importin-beta N-terminal domain RVT_1 PF00078.27 CDJ83526.1 - 0.0035 16.9 0.0 0.0035 16.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp PF00026.23 CDJ83527.1 - 7.9e-89 298.2 2.6 1e-88 297.8 2.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ83527.1 - 2.8e-10 40.7 7.3 2.4e-09 37.6 7.3 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ83527.1 - 0.00018 21.3 0.0 0.00055 19.7 0.0 1.8 1 1 1 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CDJ83527.1 - 0.00099 19.7 0.0 1.7 9.4 0.0 3.1 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 CDJ83527.1 - 0.086 13.4 0.0 7.7 7.2 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Aldedh PF00171.22 CDJ83528.1 - 1.8e-06 26.8 0.5 1.8e-06 26.7 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Eaf7 PF07904.13 CDJ83534.1 - 9.8e-13 48.4 0.0 2.3e-12 47.2 0.0 1.6 1 1 0 1 1 1 1 Chromatin modification-related protein EAF7 UMPH-1 PF05822.12 CDJ83534.1 - 0.0081 15.7 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Zip PF02535.22 CDJ83535.1 - 1.6e-24 86.8 0.1 1.7e-24 86.7 0.1 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Linker_histone PF00538.19 CDJ83536.1 - 1e-26 93.1 1.4 2e-26 92.1 1.4 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family ANAPC4_WD40 PF12894.7 CDJ83536.1 - 1.5e-07 31.6 0.0 0.0024 18.1 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ83536.1 - 0.00052 20.8 1.6 0.0057 17.5 0.3 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat MAP65_ASE1 PF03999.12 CDJ83536.1 - 0.33 9.6 3.2 0.56 8.8 3.2 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) 7tm_1 PF00001.21 CDJ83537.1 - 1.8e-08 34.0 9.9 4.5e-08 32.7 9.9 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MgtE PF01769.16 CDJ83537.1 - 0.091 13.1 4.4 0.14 12.6 4.4 1.4 1 0 0 1 1 1 0 Divalent cation transporter ADAM_CR_2 PF17771.1 CDJ83538.1 - 4.3e-15 56.0 3.0 8.8e-15 55.0 3.0 1.6 1 0 0 1 1 1 1 ADAM cysteine-rich domain Reprolysin PF01421.19 CDJ83538.1 - 8.1e-15 55.2 0.0 1.3e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.6 CDJ83538.1 - 8.4e-12 45.7 0.0 1.3e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CDJ83538.1 - 3.8e-11 43.5 1.3 8.1e-11 42.4 1.3 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 CDJ83538.1 - 7e-09 35.9 2.0 7.2e-09 35.8 0.5 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CDJ83538.1 - 4.5e-06 26.5 0.0 6.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 CDJ83538.1 - 0.047 13.3 0.1 0.08 12.6 0.1 1.3 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 CDJ83538.1 - 0.053 13.4 0.0 0.084 12.7 0.0 1.3 1 0 0 1 1 1 0 Matrixin DUF3507 PF12015.8 CDJ83539.1 - 0.046 13.4 0.6 0.23 11.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3507) eIF3_subunit PF08597.10 CDJ83541.1 - 0.064 13.2 8.9 0.099 12.5 8.9 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit OST-HTH PF12872.7 CDJ83541.1 - 0.18 11.7 0.0 0.51 10.2 0.0 1.8 1 0 0 1 1 1 0 OST-HTH/LOTUS domain LAP1C PF05609.12 CDJ83541.1 - 0.3 10.1 8.0 0.4 9.7 8.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) ALMT PF11744.8 CDJ83541.1 - 1.8 7.3 7.7 2.1 7.1 7.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter UPF0449 PF15136.6 CDJ83541.1 - 1.8 9.0 12.7 2.4 8.7 9.2 2.9 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 KxDL PF10241.9 CDJ83541.1 - 3.4 8.0 8.9 17 5.8 0.7 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein SLC12 PF03522.15 CDJ83541.1 - 6.5 5.7 7.4 8.8 5.2 7.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Adaptin_N PF01602.20 CDJ83543.1 - 1.6e-160 535.2 14.8 2.1e-160 534.8 14.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CDJ83543.1 - 9.7e-64 214.3 17.2 4.6e-63 212.1 2.1 4.0 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 CDJ83543.1 - 2.3e-30 105.0 1.7 6.6e-30 103.5 1.7 1.9 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 CDJ83543.1 - 8e-21 74.2 4.2 1.8e-07 31.4 0.1 6.1 2 2 3 6 6 6 4 HEAT repeats HEAT PF02985.22 CDJ83543.1 - 4.8e-10 38.8 7.6 0.021 15.1 0.0 6.8 8 0 0 8 8 6 3 HEAT repeat Alpha_adaptinC2 PF02883.20 CDJ83543.1 - 3.3e-09 37.1 0.0 8.8e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd3 PF12719.7 CDJ83543.1 - 5.1e-06 25.9 3.0 0.0005 19.4 0.1 3.4 2 2 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 CDJ83543.1 - 8.5e-06 25.5 3.2 0.068 12.7 0.1 4.3 2 2 1 3 3 3 2 CLASP N terminal Arm PF00514.23 CDJ83543.1 - 5e-05 23.2 0.9 0.6 10.2 0.0 4.4 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 CDJ83543.1 - 0.00034 20.8 2.8 2 8.6 0.0 4.9 1 1 2 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 CDJ83543.1 - 0.0024 18.3 0.1 31 5.2 0.0 4.9 4 0 0 4 4 4 0 HEAT-like repeat Sec7_N PF12783.7 CDJ83543.1 - 0.011 15.7 0.3 0.011 15.7 0.3 3.2 2 1 2 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Phage_TAC_12 PF12363.8 CDJ83543.1 - 0.056 13.9 0.8 5.2 7.5 0.3 2.9 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC Alpha_adaptin_C PF02296.16 CDJ83543.1 - 0.078 13.2 1.7 0.2 11.8 0.3 2.4 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain UNC45-central PF11701.8 CDJ83543.1 - 0.12 12.3 0.8 8.3 6.4 0.0 3.3 4 0 0 4 4 3 0 Myosin-binding striated muscle assembly central RasGEF_N_2 PF14663.6 CDJ83543.1 - 0.22 12.0 3.4 4.3 7.8 0.2 4.1 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain G-alpha PF00503.20 CDJ83544.1 - 7e-32 111.0 1.7 8.3e-32 110.7 1.7 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDJ83544.1 - 0.00017 21.1 0.4 0.0027 17.2 0.4 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family AIRS_C PF02769.22 CDJ83544.1 - 0.041 14.0 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 AIR synthase related protein, C-terminal domain MMR_HSR1 PF01926.23 CDJ83544.1 - 0.057 13.5 0.0 0.24 11.5 0.0 2.1 1 1 1 2 2 2 0 50S ribosome-binding GTPase bZIP_1 PF00170.21 CDJ83545.1 - 2.3e-17 62.9 15.3 2.3e-17 62.9 15.3 1.9 2 1 0 2 2 2 1 bZIP transcription factor pKID PF02173.17 CDJ83545.1 - 4.4e-16 58.1 1.8 4.4e-16 58.1 1.8 1.7 2 0 0 2 2 2 1 pKID domain bZIP_2 PF07716.15 CDJ83545.1 - 1.3e-07 31.6 12.1 1.3e-07 31.6 12.1 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 CDJ83545.1 - 0.00067 20.1 4.8 0.00067 20.1 4.8 1.6 2 0 0 2 2 2 1 bZIP Maf transcription factor Pkinase_Tyr PF07714.17 CDJ83546.1 - 2.2e-83 279.5 0.0 3.1e-83 279.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ83546.1 - 1.2e-46 159.3 0.0 1.9e-45 155.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 CDJ83546.1 - 0.00058 19.8 0.0 0.0041 17.1 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDJ83546.1 - 0.0092 15.0 0.0 0.019 13.9 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CDJ83546.1 - 0.011 15.1 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDJ83546.1 - 0.037 13.3 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like GAS PF13851.6 CDJ83547.1 - 2e-05 24.0 43.7 0.00017 21.0 8.2 4.5 2 2 0 4 4 4 3 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 CDJ83547.1 - 0.0038 17.1 47.1 0.019 14.8 15.0 4.8 1 1 1 3 3 3 1 Coiled-coil region of CCDC155 or KASH SlyX PF04102.12 CDJ83547.1 - 0.38 11.4 30.7 0.29 11.8 0.5 7.2 5 2 2 7 7 7 0 SlyX IFP_35_N PF07334.13 CDJ83547.1 - 1.3 9.2 20.4 0.44 10.6 0.4 5.7 4 2 2 6 6 6 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Taxilin PF09728.9 CDJ83547.1 - 1.7 7.7 38.5 0.27 10.4 10.0 4.0 3 1 0 3 3 3 0 Myosin-like coiled-coil protein NPV_P10 PF05531.12 CDJ83547.1 - 2.2 8.8 11.9 0.34 11.4 0.3 4.0 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 CDJ83547.1 - 2.4 6.9 47.9 0.015 14.2 13.6 4.2 2 1 2 4 4 4 0 Spc7 kinetochore protein TLE_N PF03920.15 CDJ83547.1 - 2.5 8.2 7.4 19 5.3 0.1 3.7 4 0 0 4 4 4 0 Groucho/TLE N-terminal Q-rich domain Cnn_1N PF07989.11 CDJ83547.1 - 2.6 8.2 36.5 0.12 12.6 3.1 6.3 3 3 4 7 7 7 0 Centrosomin N-terminal motif 1 Sec2p PF06428.11 CDJ83547.1 - 5.2 7.1 36.8 0.46 10.5 1.9 6.0 4 2 2 6 6 6 0 GDP/GTP exchange factor Sec2p HALZ PF02183.18 CDJ83547.1 - 7.2 6.9 47.6 0.15 12.3 2.8 7.2 8 0 0 8 8 8 0 Homeobox associated leucine zipper Tropomyosin_1 PF12718.7 CDJ83547.1 - 7.2 6.8 48.9 0.57 10.3 14.4 4.8 3 2 1 4 4 4 0 Tropomyosin like DivIC PF04977.15 CDJ83547.1 - 7.2 6.5 55.5 1.4 8.7 4.7 8.8 5 3 3 9 9 9 0 Septum formation initiator CtIP_N PF10482.9 CDJ83547.1 - 7.8 6.6 33.7 0.033 14.2 6.6 3.9 3 1 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain ATG16 PF08614.11 CDJ83547.1 - 8.2 6.6 65.1 1.2 9.3 12.1 5.8 3 2 2 6 6 6 0 Autophagy protein 16 (ATG16) DnaJ_C PF01556.18 CDJ83548.1 - 2.6e-41 141.1 0.1 4.4e-41 140.4 0.1 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CDJ83548.1 - 1.3e-23 82.9 2.3 1.3e-23 82.9 2.3 1.8 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CDJ83548.1 - 1.2e-13 51.2 18.8 2e-13 50.5 18.8 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CDJ83548.1 - 0.19 11.7 14.3 0.25 11.3 3.0 2.4 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CDJ83548.1 - 0.23 11.5 9.8 2.1 8.4 2.9 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 CDJ83548.1 - 6.4 6.9 10.4 7.7 6.6 3.0 2.5 2 0 0 2 2 2 0 Double zinc ribbon HTH_48 PF17906.1 CDJ83549.1 - 1.5e-15 57.0 0.0 1.4e-14 53.9 0.0 2.1 2 0 0 2 2 2 1 HTH domain in Mos1 transposase HTH_24 PF13412.6 CDJ83549.1 - 0.00068 19.1 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_50 PF18024.1 CDJ83549.1 - 0.0068 16.0 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AsnC-type PF13404.6 CDJ83549.1 - 0.013 15.3 0.1 0.027 14.3 0.1 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain GSHPx PF00255.19 CDJ83550.1 - 3.5e-39 132.7 0.4 4.8e-39 132.3 0.4 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CDJ83550.1 - 1.8e-10 40.8 0.2 1.1e-09 38.3 0.1 2.0 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 CDJ83550.1 - 2.4e-07 30.6 0.3 7.4e-06 25.7 0.3 2.5 1 1 0 1 1 1 1 Redoxin DUF3399 PF11879.8 CDJ83551.1 - 0.034 14.5 0.3 0.091 13.1 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) XhlA PF10779.9 CDJ83551.1 - 2.7 8.2 10.9 0.13 12.5 2.0 3.0 3 0 0 3 3 3 0 Haemolysin XhlA SecD-TM1 PF13721.6 CDJ83551.1 - 3.3 8.2 7.3 1.5 9.3 0.6 2.7 2 1 0 2 2 2 0 SecD export protein N-terminal TM region Pkinase PF00069.25 CDJ83552.1 - 2.3e-66 223.9 0.0 2.9e-66 223.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ83552.1 - 8.8e-45 153.0 0.0 1e-44 152.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ83552.1 - 9.9e-08 31.6 0.0 6.3e-07 29.0 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CDJ83552.1 - 1.2e-06 27.7 0.2 2.4e-06 26.8 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CDJ83552.1 - 2.1e-06 26.8 0.0 4.3e-06 25.8 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDJ83552.1 - 0.0058 16.0 0.2 0.0095 15.3 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 CDJ83552.1 - 0.0092 15.6 0.1 2.5 7.7 0.1 2.4 2 0 0 2 2 2 2 Protein-kinase domain of FAM69 APH PF01636.23 CDJ83552.1 - 0.059 13.3 0.0 0.19 11.6 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 CDJ83552.1 - 0.12 11.9 0.5 1.1 8.9 0.1 2.0 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RRM_1 PF00076.22 CDJ83554.1 - 3.5e-37 126.0 0.1 1.9e-13 50.0 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) hnRNP_Q_AcD PF18360.1 CDJ83554.1 - 6.2e-28 96.6 0.7 1.2e-27 95.6 0.7 1.5 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain RRM_5 PF13893.6 CDJ83554.1 - 0.0008 19.0 0.0 0.003 17.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.12 CDJ83554.1 - 0.003 17.8 0.1 0.091 13.0 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif 2 RRM_occluded PF16842.5 CDJ83554.1 - 0.0085 15.9 0.0 0.13 12.2 0.0 2.7 3 1 0 3 3 3 1 Occluded RNA-recognition motif HMG_box PF00505.19 CDJ83555.1 - 2.8e-16 59.7 4.8 2.8e-16 59.7 4.8 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ83555.1 - 4.8e-09 36.7 5.9 9.4e-09 35.7 5.9 1.5 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 CDJ83555.1 - 0.001 19.0 6.4 0.001 19.0 6.4 2.4 2 1 0 2 2 2 1 HMG (high mobility group) box 5 HTH_Tnp_ISL3 PF13542.6 CDJ83555.1 - 0.082 12.3 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Collagen PF01391.18 CDJ83556.1 - 9.5e-27 92.5 138.8 2.7e-10 39.9 34.5 4.0 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ83556.1 - 0.059 13.4 0.5 0.078 13.1 0.5 1.2 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Tctex-1 PF03645.13 CDJ83557.1 - 6.6e-22 77.7 0.8 7.6e-22 77.5 0.8 1.1 1 0 0 1 1 1 1 Tctex-1 family Methyltransf_23 PF13489.6 CDJ83557.1 - 0.072 12.9 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Imm74 PF15603.6 CDJ83557.1 - 0.13 12.5 0.2 0.29 11.4 0.1 1.7 2 0 0 2 2 2 0 Immunity protein 74 Glycos_transf_2 PF00535.26 CDJ83559.1 - 5.7e-17 62.0 0.0 1.1e-16 61.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 CDJ83559.1 - 6.1e-12 45.6 0.0 1.1e-10 41.5 0.0 2.3 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 CDJ83559.1 - 6.3e-09 36.1 0.0 8.7e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 CDJ83559.1 - 0.00012 22.6 0.0 0.0031 18.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 zf-DNL PF05180.12 CDJ83560.1 - 1.1e-27 95.7 0.5 1.5e-27 95.3 0.5 1.2 1 0 0 1 1 1 1 DNL zinc finger PDH PF02153.17 CDJ83560.1 - 0.032 13.2 0.0 0.042 12.9 0.0 1.1 1 0 0 1 1 1 0 Prephenate dehydrogenase Stc1 PF12898.7 CDJ83560.1 - 0.093 13.3 0.6 0.18 12.4 0.6 1.5 1 1 0 1 1 1 0 Stc1 domain zf-RING_7 PF02591.15 CDJ83560.1 - 0.15 12.3 2.5 0.34 11.1 2.5 1.6 1 1 0 1 1 1 0 C4-type zinc ribbon domain SHMT PF00464.19 CDJ83560.1 - 0.15 10.6 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Serine hydroxymethyltransferase Coq4 PF05019.13 CDJ83561.1 - 9.9e-78 260.5 0.1 1.1e-77 260.3 0.1 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 P16-Arc PF04699.14 CDJ83562.1 - 3.6e-43 147.6 0.0 4e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) PigN PF04987.14 CDJ83563.1 - 1.8e-66 224.9 45.5 6.5e-64 216.5 34.8 2.4 2 1 1 3 3 3 2 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 CDJ83563.1 - 3.9e-09 36.6 0.9 6.8e-08 32.5 0.9 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CDJ83563.1 - 1.3e-08 34.6 0.1 1.8e-08 34.1 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 CDJ83563.1 - 0.0014 18.0 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.12 CDJ83563.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 PglZ domain Amnionless PF14828.6 CDJ83564.1 - 0.12 11.2 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Amnionless Prominin PF05478.11 CDJ83564.1 - 0.13 10.2 0.1 0.16 9.9 0.1 1.1 1 0 0 1 1 1 0 Prominin SARAF PF06682.12 CDJ83564.1 - 0.51 9.9 0.0 0.51 9.9 0.0 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis LapA_dom PF06305.11 CDJ83564.1 - 0.75 9.7 1.8 1.2 9.0 1.8 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain OAD_gamma PF04277.13 CDJ83564.1 - 0.97 10.1 0.0 0.97 10.1 0.0 3.5 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Plasmodium_Vir PF05795.11 CDJ83564.1 - 2.5 7.4 13.6 69 2.7 13.6 2.1 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Lin-8 PF03353.15 CDJ83565.1 - 0.97 8.9 7.1 1.5 8.3 7.1 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Dicty_REP PF05086.12 CDJ83565.1 - 1.4 6.8 12.3 2 6.3 12.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PARM PF17061.5 CDJ83565.1 - 5.1 7.2 30.3 7.1 6.7 30.3 1.2 1 0 0 1 1 1 0 PARM SRP-alpha_N PF04086.13 CDJ83565.1 - 6.6 6.6 12.2 11 5.8 12.2 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal HECT PF00632.25 CDJ83566.1 - 1.7e-84 283.9 0.0 2.2e-84 283.6 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RNA_pol_3_Rpc31 PF11705.8 CDJ83566.1 - 0.12 12.6 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NKAIN PF05640.14 CDJ83567.1 - 1e-07 31.4 1.2 1.8e-07 30.6 1.2 1.3 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein Dynamitin PF04912.14 CDJ83569.1 - 2.4e-52 178.6 15.4 2.3e-27 96.3 2.8 2.0 1 1 0 2 2 2 2 Dynamitin HJURP_C PF12347.8 CDJ83569.1 - 0.099 12.7 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat Noelin-1 PF12308.8 CDJ83569.1 - 0.12 12.4 1.6 3 7.9 0.0 3.3 2 1 1 3 3 3 0 Neurogenesis glycoprotein DUF1284 PF06935.11 CDJ83569.1 - 0.18 12.3 0.5 2.5 8.6 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1284) DUF1664 PF07889.12 CDJ83569.1 - 0.2 11.7 10.4 0.36 10.9 1.5 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 CDJ83569.1 - 0.36 11.1 12.6 1.1 9.5 0.1 4.6 3 2 1 4 4 4 0 ABC transporter C-terminal domain VasL PF12486.8 CDJ83569.1 - 0.46 10.3 5.0 5.2 6.9 0.1 3.6 3 1 1 4 4 4 0 Type VI secretion system, EvfB, or VasL Spc7 PF08317.11 CDJ83569.1 - 0.85 8.4 8.8 0.47 9.3 2.5 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein PspB PF06667.12 CDJ83569.1 - 0.85 9.7 4.4 28 4.8 0.4 3.4 3 0 0 3 3 3 0 Phage shock protein B SLATT_1 PF18181.1 CDJ83569.1 - 0.85 9.6 2.5 20 5.1 0.1 2.6 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 Phasin PF05597.11 CDJ83569.1 - 1.6 8.8 8.8 1.9 8.5 4.2 3.0 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) XhlA PF10779.9 CDJ83569.1 - 1.9 8.7 13.7 12 6.2 0.2 4.6 4 1 1 5 5 5 0 Haemolysin XhlA SAP30_Sin3_bdg PF13867.6 CDJ83570.1 - 1.6e-13 50.8 0.0 2.9e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 zf-SAP30 PF13866.6 CDJ83570.1 - 0.0029 17.7 1.9 0.0046 17.0 0.0 2.2 2 1 0 2 2 2 1 SAP30 zinc-finger tRNA-synt_2 PF00152.20 CDJ83571.1 - 4.1e-68 229.8 0.0 5.4e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Collagen PF01391.18 CDJ83571.1 - 2.6e-16 59.1 83.9 6e-08 32.3 32.4 4.3 4 0 0 4 4 4 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ83571.1 - 3.2e-12 46.3 0.6 6.5e-12 45.3 0.1 1.8 2 0 0 2 2 2 1 Nematode cuticle collagen N-terminal domain RNase_P_Rpp14 PF01900.19 CDJ83572.1 - 4.1e-17 62.3 0.0 7.6e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Rpp14/Pop5 family Spore_SspJ PF09575.10 CDJ83572.1 - 0.016 15.6 0.5 0.029 14.7 0.5 1.3 1 0 0 1 1 1 0 Small spore protein J (Spore_SspJ) RT_RNaseH PF17917.1 CDJ83573.1 - 4.1e-34 117.0 0.0 6.2e-34 116.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ83573.1 - 7.2e-26 90.1 0.0 1.3e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Peptidase_A17 PF05380.13 CDJ83573.1 - 0.016 15.3 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Pao retrotransposon peptidase DUF273 PF03314.14 CDJ83574.1 - 6.2e-54 182.8 0.3 7.5e-54 182.6 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Nucleotid_trans PF03407.16 CDJ83574.1 - 0.0016 18.5 0.4 0.0026 17.8 0.3 1.4 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase MFS_1 PF07690.16 CDJ83575.1 - 4e-28 98.4 18.2 4.6e-28 98.2 18.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ83575.1 - 2e-10 40.2 12.2 2.5e-10 39.8 12.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 CDJ83575.1 - 7.9e-08 31.0 7.9 0.00083 17.8 1.0 2.0 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 CDJ83575.1 - 9.2e-05 21.2 11.9 0.00012 20.8 11.9 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_4 PF06779.14 CDJ83575.1 - 0.001 18.4 4.9 0.0012 18.2 4.9 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB EMP70 PF02990.16 CDJ83575.1 - 0.036 12.7 6.4 0.049 12.3 6.4 1.4 1 1 0 1 1 1 0 Endomembrane protein 70 UNC-93 PF05978.16 CDJ83575.1 - 0.048 13.4 6.2 0.065 13.0 6.2 1.3 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 TMEM40 PF15817.5 CDJ83575.1 - 0.47 10.2 2.3 1.2 9.0 1.9 1.8 2 0 0 2 2 2 0 Transmembrane protein 40 family CRAL_TRIO PF00650.20 CDJ83576.1 - 2.2e-20 73.0 0.0 3e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CDJ83576.1 - 0.019 15.1 0.0 0.039 14.1 0.0 1.6 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain GnsAB_toxin PF08178.11 CDJ83576.1 - 0.12 12.3 0.2 0.58 10.1 0.1 2.2 2 0 0 2 2 2 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system MIOX PF05153.15 CDJ83577.1 - 1.6e-113 378.4 4.8 1.9e-113 378.2 4.8 1.0 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 CDJ83577.1 - 0.016 15.4 0.3 0.096 12.9 0.0 2.3 3 0 0 3 3 3 0 HD domain HDOD PF08668.12 CDJ83577.1 - 0.18 11.2 0.0 0.74 9.3 0.0 1.9 2 0 0 2 2 2 0 HDOD domain HNOBA PF07701.14 CDJ83578.1 - 2.8e-42 144.6 2.7 8.9e-42 143.0 2.7 1.8 1 1 0 1 1 1 1 Heme NO binding associated Guanylate_cyc PF00211.20 CDJ83578.1 - 8.1e-15 54.9 0.1 1.3e-09 37.9 0.0 2.8 2 1 1 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain HNOB PF07700.15 CDJ83578.1 - 1.5e-10 41.3 0.0 2.8e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Haem-NO-binding zf-H2C2_2 PF13465.6 CDJ83579.1 - 0.032 14.7 1.9 0.032 14.7 1.9 2.9 3 0 0 3 3 3 0 Zinc-finger double domain TrbI PF03743.14 CDJ83580.1 - 0.073 12.9 0.1 0.079 12.8 0.1 1.0 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein DUF2423 PF10338.9 CDJ83580.1 - 1.9 8.8 5.8 17 5.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) Col_cuticle_N PF01484.17 CDJ83581.1 - 9.3e-16 57.6 2.1 9.3e-16 57.6 2.1 1.6 2 0 0 2 2 2 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ83581.1 - 3.2e-11 42.8 146.7 1.6e-05 24.5 48.0 4.3 1 1 2 3 3 3 1 Collagen triple helix repeat (20 copies) Ribosomal_L21p PF00829.21 CDJ83582.1 - 1.4e-34 118.4 5.6 1.5e-34 118.2 5.6 1.0 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein DUF229 PF02995.17 CDJ83583.1 - 1.1e-41 143.0 0.1 7.2e-41 140.3 0.0 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF229) Ribosomal_L30_N PF08079.12 CDJ83584.1 - 6.4e-25 87.2 13.4 1e-24 86.6 13.4 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 CDJ83584.1 - 1.5e-18 66.4 1.6 4.6e-18 64.8 1.6 1.9 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ras PF00071.22 CDJ83585.1 - 5.4e-63 211.4 0.5 6.4e-63 211.2 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ83585.1 - 1.1e-35 122.4 0.2 2e-35 121.6 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ83585.1 - 6.9e-13 48.4 0.1 8.9e-13 48.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ83585.1 - 8.4e-08 32.3 0.1 1.3e-07 31.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ83585.1 - 1.9e-05 24.3 0.3 9.1e-05 22.1 0.3 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CDJ83585.1 - 0.0001 22.6 0.0 0.0023 18.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CDJ83585.1 - 0.0001 22.2 0.4 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 CDJ83585.1 - 0.00046 19.6 0.1 0.00079 18.8 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 CDJ83585.1 - 0.0054 16.3 0.3 0.014 14.9 0.3 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 CDJ83585.1 - 0.0079 15.6 0.0 0.015 14.7 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CDJ83585.1 - 0.0091 16.4 0.1 0.014 15.8 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 CDJ83585.1 - 0.015 15.3 0.1 0.039 14.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDJ83585.1 - 0.016 15.7 0.1 0.029 14.9 0.1 1.6 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 CDJ83585.1 - 0.024 14.4 0.0 0.079 12.7 0.0 1.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FAD-SLDH PF12318.8 CDJ83585.1 - 0.024 14.7 0.2 0.048 13.7 0.1 1.5 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase TniB PF05621.11 CDJ83585.1 - 0.049 13.0 0.1 0.19 11.1 0.0 1.9 2 1 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 CDJ83585.1 - 0.067 12.9 0.1 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 CDJ83585.1 - 0.11 12.3 0.1 0.24 11.2 0.1 1.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 CDJ83585.1 - 0.12 11.8 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 CDJ83585.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AT_hook PF02178.19 CDJ83586.1 - 1.9 8.7 6.8 6.3 7.0 6.8 2.0 1 0 0 1 1 1 0 AT hook motif HTH_26 PF13443.6 CDJ83587.1 - 0.00032 21.1 0.0 0.00064 20.1 0.0 1.5 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain Sigma70_r4_2 PF08281.12 CDJ83587.1 - 0.0034 17.0 0.2 0.47 10.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_IclR PF09339.10 CDJ83587.1 - 0.0058 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.6 CDJ83587.1 - 0.0066 16.0 0.0 0.036 13.6 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 CDJ83587.1 - 0.018 15.0 0.1 0.041 13.8 0.1 1.6 1 0 0 1 1 1 0 MarR family CENP-B_N PF04218.13 CDJ83587.1 - 0.018 14.6 0.1 0.041 13.5 0.1 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain E3_UFM1_ligase PF09743.9 CDJ83587.1 - 0.039 13.6 0.0 0.079 12.6 0.0 1.4 2 0 0 2 2 2 0 E3 UFM1-protein ligase 1 HTH_Tnp_ISL3 PF13542.6 CDJ83587.1 - 0.069 12.6 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF3602 PF12223.8 CDJ83587.1 - 0.084 13.5 0.2 0.19 12.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) LacI PF00356.21 CDJ83587.1 - 0.09 12.6 0.3 0.44 10.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_AsnC-type PF13404.6 CDJ83587.1 - 0.11 12.4 0.2 0.68 9.8 0.1 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_38 PF13936.6 CDJ83587.1 - 1.3 8.8 4.4 1 9.2 0.2 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain RVT_1 PF00078.27 CDJ83588.1 - 0.042 13.4 0.1 0.06 12.8 0.1 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Guanylate_cyc PF00211.20 CDJ83590.1 - 5.4e-69 231.5 0.0 8.9e-69 230.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 CDJ83590.1 - 2.3e-49 168.4 0.2 4.7e-49 167.4 0.1 1.5 2 0 0 2 2 2 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 CDJ83590.1 - 2e-34 119.1 0.0 4.4e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ83590.1 - 4.3e-32 111.5 0.0 8.9e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 CDJ83590.1 - 0.011 15.1 0.6 0.011 15.1 0.6 1.8 2 0 0 2 2 2 0 Heme NO binding associated HAD_2 PF13419.6 CDJ83592.1 - 0.055 13.5 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF3741 PF12552.8 CDJ83593.1 - 0.035 14.1 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3741) tRNA-synt_His PF13393.6 CDJ83593.1 - 0.16 11.2 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Kinesin PF00225.23 CDJ83595.1 - 9.7e-34 116.8 0.0 1.1e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ83595.1 - 2e-21 76.5 0.0 2.6e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding Bac_DnaA PF00308.18 CDJ83595.1 - 0.095 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_22 PF13401.6 CDJ83595.1 - 0.12 12.7 0.0 0.34 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 CDJ83595.1 - 0.18 11.9 3.6 0.35 10.9 1.2 2.5 2 1 0 2 2 2 0 Helicase HerA, central domain TSGP1 PF07771.11 CDJ83596.1 - 0.037 14.2 0.2 0.037 14.2 0.2 1.8 2 0 0 2 2 2 0 Tick salivary peptide group 1 SOG2 PF10428.9 CDJ83596.1 - 0.089 12.0 12.3 0.085 12.0 12.3 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Zip PF02535.22 CDJ83596.1 - 0.13 11.4 1.4 0.18 11.0 1.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4834 PF16118.5 CDJ83596.1 - 0.19 12.7 1.8 0.43 11.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) NST1 PF13945.6 CDJ83596.1 - 0.19 11.8 11.8 0.27 11.3 11.8 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator AP3D1 PF06375.11 CDJ83596.1 - 1 9.6 13.4 0.72 10.1 12.0 1.5 1 1 1 2 2 2 0 AP-3 complex subunit delta-1 DUF2615 PF11027.8 CDJ83596.1 - 1.2 9.4 5.6 0.43 10.7 1.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2615) Ribosomal_S7e PF01251.18 CDJ83597.1 - 9.7e-81 269.9 5.4 1.1e-80 269.8 5.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e AlbA_2 PF04326.14 CDJ83597.1 - 0.039 14.3 0.9 5 7.5 0.1 2.2 2 0 0 2 2 2 0 Putative DNA-binding domain GAPES4 PF17157.4 CDJ83597.1 - 0.084 13.3 0.1 1.6 9.2 0.0 2.3 2 1 0 2 2 2 0 Gammaproteobacterial periplasmic sensor domain dCache_3 PF14827.6 CDJ83597.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.4 1 1 0 1 1 1 0 Double sensory domain of two-component sensor kinase SL4P PF17618.2 CDJ83598.1 - 5e-19 68.1 0.0 6.9e-19 67.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized Strongylid L4 protein Ion_trans PF00520.31 CDJ83601.1 - 2e-17 63.3 19.8 2.8e-17 62.8 19.8 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 CDJ83601.1 - 0.0015 17.3 11.0 0.0015 17.3 11.0 1.7 3 0 0 3 3 3 1 Polycystin cation channel SUA5 PF03481.13 CDJ83601.1 - 0.18 12.4 0.0 0.35 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative GTP-binding controlling metal-binding DUF4131 PF13567.6 CDJ83601.1 - 5.1 6.7 5.6 9.1 5.9 2.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ThiF PF00899.21 CDJ83602.1 - 1.1e-99 332.8 0.0 7.9e-70 235.0 0.0 2.3 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 CDJ83602.1 - 1.3e-89 300.5 4.1 2.5e-89 299.6 4.1 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 CDJ83602.1 - 1.2e-28 99.6 0.3 3.7e-28 98.1 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin fold domain E1_FCCH PF16190.5 CDJ83602.1 - 3.6e-25 88.0 1.1 8.1e-25 86.8 1.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 CDJ83602.1 - 6.1e-17 61.6 0.1 1.7e-16 60.2 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle 2-Hacid_dh_C PF02826.19 CDJ83602.1 - 0.00031 20.2 0.1 0.27 10.6 0.0 2.9 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 CDJ83602.1 - 0.0016 18.8 2.5 0.011 16.1 0.0 3.2 3 0 0 3 3 3 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 CDJ83602.1 - 0.0061 16.6 2.7 7.7 6.6 0.2 3.5 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 CDJ83602.1 - 0.034 14.7 2.0 1.3 9.6 0.4 3.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MAM PF00629.23 CDJ83605.1 - 3.8e-10 39.9 0.0 0.02 14.8 0.0 4.2 4 0 0 4 4 4 3 MAM domain, meprin/A5/mu CBM_48 PF02922.18 CDJ83605.1 - 0.011 16.1 0.0 0.36 11.2 0.0 2.7 3 0 0 3 3 3 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Exo_endo_phos_2 PF14529.6 CDJ83607.1 - 3.3e-05 23.7 0.0 8.7e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ83607.1 - 0.00014 21.4 0.0 0.00035 20.2 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family STAS PF01740.21 CDJ83608.1 - 1.9e-29 101.7 0.1 6.3e-29 100.0 0.0 1.8 2 0 0 2 2 2 1 STAS domain Gluconate_2-dh3 PF13618.6 CDJ83608.1 - 0.15 12.3 3.1 0.42 10.9 3.1 1.9 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 U79_P34 PF03064.16 CDJ83608.1 - 0.2 11.0 9.7 0.33 10.3 9.7 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF2981 PF11200.8 CDJ83608.1 - 0.41 10.3 3.6 0.54 10.0 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Phi-29_GP16_7 PF06720.11 CDJ83608.1 - 3.6 7.4 4.8 1.5 8.6 0.1 2.5 2 1 0 2 2 2 0 Bacteriophage phi-29 early protein GP16.7 RVT_1 PF00078.27 CDJ83609.1 - 7.2e-11 42.0 0.0 7.7e-11 41.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sulfate_transp PF00916.20 CDJ83610.1 - 3.2e-69 233.5 16.9 4.7e-69 233.0 16.9 1.2 1 0 0 1 1 1 1 Sulfate permease family RNA_pol_Rpb1_5 PF04998.17 CDJ83611.1 - 1.1e-82 277.5 0.3 1.6e-82 277.0 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.17 CDJ83611.1 - 5.5e-31 106.7 0.0 1.2e-30 105.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DinB_2 PF12867.7 CDJ83612.1 - 0.089 13.3 0.2 0.089 13.3 0.2 1.8 2 0 0 2 2 2 0 DinB superfamily RVT_1 PF00078.27 CDJ83613.1 - 5.9e-19 68.5 0.0 1.4e-18 67.2 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) NPR2 PF06218.11 CDJ83614.1 - 3.7e-85 286.3 5.2 2.2e-67 227.8 4.3 3.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 Afi1 PF07792.12 CDJ83614.1 - 0.0036 17.8 0.1 0.0058 17.1 0.1 1.3 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking IBP39 PF11422.8 CDJ83614.1 - 0.17 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Initiator binding protein 39 kDa Pedibin PF08182.11 CDJ83615.1 - 0.024 14.4 0.6 0.04 13.7 0.6 1.4 1 0 0 1 1 1 0 Pedibin/Hym-346 family SSF PF00474.17 CDJ83616.1 - 1.9e-24 86.3 11.8 2.3e-24 86.0 11.8 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family DUF4149 PF13664.6 CDJ83616.1 - 8.1 6.8 16.3 1.1 9.6 1.3 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) Mlf1IP PF10248.9 CDJ83617.1 - 2.8e-41 141.4 8.0 2.6e-40 138.2 3.1 2.2 2 0 0 2 2 2 2 Myelodysplasia-myeloid leukemia factor 1-interacting protein Noc2 PF03715.13 CDJ83618.1 - 3.1e-80 269.6 3.2 3.1e-80 269.6 3.2 2.3 3 0 0 3 3 3 1 Noc2p family SET PF00856.28 CDJ83618.1 - 4.3 7.7 6.1 3.9 7.8 0.6 2.5 2 0 0 2 2 2 0 SET domain GCFC PF07842.12 CDJ83619.1 - 1.8e-71 241.0 14.4 2.7e-71 240.4 14.4 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 CDJ83619.1 - 2.8e-20 72.6 1.8 5.7e-20 71.6 1.8 1.4 1 0 0 1 1 1 1 Tuftelin interacting protein N terminal G-patch PF01585.23 CDJ83619.1 - 1.1e-13 50.9 2.2 1.1e-13 50.9 2.2 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 CDJ83619.1 - 0.0016 18.4 1.2 0.0039 17.2 1.2 1.6 1 0 0 1 1 1 1 G-patch domain HTH_48 PF17906.1 CDJ83619.1 - 0.43 10.7 1.5 1.6 8.9 0.1 2.5 3 0 0 3 3 3 0 HTH domain in Mos1 transposase Folliculin PF11704.8 CDJ83620.1 - 0.00037 20.4 0.1 0.0048 16.8 0.0 1.9 1 1 1 2 2 2 2 Vesicle coat protein involved in Golgi to plasma membrane transport Dynactin PF12455.8 CDJ83622.1 - 1.1e-46 159.3 0.5 1.1e-46 159.3 0.5 4.5 4 1 0 5 5 5 1 Dynein associated protein CAP_GLY PF01302.25 CDJ83622.1 - 2.7e-23 81.8 0.6 4.7e-23 81.0 0.6 1.4 1 0 0 1 1 1 1 CAP-Gly domain HMMR_N PF15905.5 CDJ83622.1 - 0.00014 21.5 11.3 0.00014 21.5 11.3 5.3 5 1 1 6 6 6 1 Hyaluronan mediated motility receptor N-terminal Dpy19 PF10034.9 CDJ83627.1 - 4.9e-189 629.7 15.5 6e-189 629.4 15.5 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation zf-C4 PF00105.18 CDJ83628.1 - 5.3e-29 100.5 14.1 5.3e-29 100.5 14.1 2.3 3 0 0 3 3 3 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ83628.1 - 6.9e-17 61.7 0.1 1.4e-16 60.7 0.1 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor LicD PF04991.13 CDJ83630.1 - 0.0052 17.0 0.2 0.87 9.7 0.0 2.8 2 1 1 3 3 3 2 LicD family WASH-7_N PF14745.6 CDJ83631.1 - 0.039 12.5 1.7 0.048 12.2 1.7 1.1 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal bZIP_2 PF07716.15 CDJ83631.1 - 0.48 10.6 6.8 0.84 9.8 6.8 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Spt20 PF12090.8 CDJ83631.1 - 0.84 9.2 10.0 1.1 8.9 10.0 1.1 1 0 0 1 1 1 0 Spt20 family KfrA_N PF11740.8 CDJ83631.1 - 2.1 9.0 10.6 3.5 8.3 10.2 1.6 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term Peptidase_M14 PF00246.24 CDJ83632.1 - 6.9e-20 72.0 0.0 9e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase ShK PF01549.24 CDJ83632.1 - 0.00016 22.2 8.9 0.00026 21.5 8.9 1.4 1 0 0 1 1 1 1 ShK domain-like DUF2397 PF09660.10 CDJ83632.1 - 0.0051 15.8 6.5 0.0071 15.3 6.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2397) PRIMA1 PF16101.5 CDJ83632.1 - 0.026 14.5 6.6 0.055 13.5 6.6 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 CDJ83632.1 - 2.2 7.7 9.0 0.084 12.3 2.7 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Med3 PF11593.8 CDJ83632.1 - 6.8 5.8 7.9 10 5.2 7.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-C2H2 PF00096.26 CDJ83633.1 - 0.00015 22.0 3.1 0.00015 22.0 3.1 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ83633.1 - 8.3 7.0 9.2 1.9 9.1 0.6 3.0 3 0 0 3 3 3 0 Zinc-finger double domain TK PF00265.18 CDJ83634.1 - 5.1e-57 192.6 0.1 5.8e-57 192.4 0.1 1.0 1 0 0 1 1 1 1 Thymidine kinase RecA PF00154.21 CDJ83634.1 - 0.025 14.1 0.1 0.24 10.8 0.0 2.1 1 1 1 2 2 2 0 recA bacterial DNA recombination protein AAA_14 PF13173.6 CDJ83634.1 - 0.035 14.1 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PI3_PI4_kinase PF00454.27 CDJ83635.1 - 2.5e-41 142.1 0.0 4.6e-41 141.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CDJ83635.1 - 8.3e-12 44.7 0.1 3.4e-11 42.8 0.0 2.2 2 0 0 2 2 2 1 FATC domain DUF5471 PF17565.2 CDJ83635.1 - 0.11 12.9 0.0 0.34 11.2 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5471) Phage_int_SAM_6 PF18644.1 CDJ83636.1 - 0.037 14.0 0.1 0.09 12.8 0.1 1.6 1 0 0 1 1 1 0 Phage integrase SAM-like domain Ank_2 PF12796.7 CDJ83637.1 - 3.2e-66 219.9 23.3 4e-12 46.5 0.1 11.0 3 2 11 14 14 14 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ83637.1 - 6.8e-50 166.8 26.2 0.00015 22.3 0.0 15.6 7 4 9 17 17 17 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ83637.1 - 2.5e-44 148.7 23.8 3.1e-08 33.7 0.1 14.1 6 4 8 15 15 15 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ83637.1 - 6.5e-43 139.8 30.4 0.0019 18.6 0.0 19.3 23 0 0 23 23 23 10 Ankyrin repeat Ank PF00023.30 CDJ83637.1 - 1.6e-29 101.1 29.2 0.0093 16.4 0.0 16.0 17 0 0 17 17 17 8 Ankyrin repeat BTB PF00651.31 CDJ83637.1 - 3.5e-11 43.3 0.3 8.9e-11 42.0 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 CDJ83637.1 - 0.064 13.4 0.2 0.33 11.1 0.0 2.2 2 0 0 2 2 2 0 BTB And C-terminal Kelch Aldolase PF01081.19 CDJ83637.1 - 0.092 12.2 0.0 0.24 10.8 0.0 1.6 2 0 0 2 2 2 0 KDPG and KHG aldolase 7tm_1 PF00001.21 CDJ83638.1 - 5.8e-10 38.9 20.2 8.8e-10 38.3 20.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SIX1_SD PF16878.5 CDJ83639.1 - 4.8e-36 123.7 4.1 1.8e-35 121.8 0.4 2.0 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 CDJ83639.1 - 6.1e-05 22.8 0.4 6.1e-05 22.8 0.4 2.5 3 0 0 3 3 3 1 Homeodomain Homeobox_KN PF05920.11 CDJ83639.1 - 0.041 13.8 0.1 0.087 12.7 0.1 1.5 1 0 0 1 1 1 0 Homeobox KN domain E3_UFM1_ligase PF09743.9 CDJ83639.1 - 0.088 12.4 0.5 2.3 7.8 0.3 2.1 2 0 0 2 2 2 0 E3 UFM1-protein ligase 1 zf-C4 PF00105.18 CDJ83640.1 - 4.5e-26 91.1 13.3 6.9e-26 90.5 13.3 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) NEAT PF05031.12 CDJ83641.1 - 0.25 12.0 5.4 0.88 10.2 5.3 1.7 1 1 0 1 1 1 0 Iron Transport-associated domain pXO2-34 PF17362.2 CDJ83641.1 - 0.3 11.0 0.8 3.4 7.6 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function DUF903 PF06004.12 CDJ83641.1 - 1.4 8.9 6.5 9.7 6.2 1.3 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF903) DUF903 PF06004.12 CDJ83642.1 - 0.055 13.4 2.6 1.8 8.5 1.0 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF903) Adipokin_hormo PF06377.11 CDJ83643.1 - 0.00018 21.8 0.0 0.25 11.7 0.0 2.3 2 0 0 2 2 2 2 Adipokinetic hormone DUF4969 PF16339.5 CDJ83644.1 - 0.2 12.0 1.9 19 5.7 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4969) GcnA_N PF18229.1 CDJ83646.1 - 0.04 13.9 0.0 0.087 12.9 0.0 1.6 1 0 0 1 1 1 0 N-acetyl-beta-D-glucosaminidase N-terminal domain AI-2E_transport PF01594.16 CDJ83646.1 - 0.061 12.5 0.1 0.088 11.9 0.1 1.1 1 0 0 1 1 1 0 AI-2E family transporter DUF5619 PF18505.1 CDJ83646.1 - 0.12 12.4 0.3 0.23 11.5 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5619) DUF903 PF06004.12 CDJ83646.1 - 6.1 6.8 8.4 2 8.4 0.3 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF903) Laminin_B PF00052.18 CDJ83649.1 - 4e-33 114.2 0.0 6.4e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 Laminin B (Domain IV) Ldl_recept_a PF00057.18 CDJ83649.1 - 1.2e-31 108.6 73.8 3.6e-13 49.5 16.3 5.0 5 0 0 5 5 5 3 Low-density lipoprotein receptor domain class A Ig_3 PF13927.6 CDJ83649.1 - 2.7e-25 88.8 1.5 1.8e-12 47.7 0.7 2.7 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 CDJ83649.1 - 7.3e-19 67.6 0.0 2.3e-09 37.2 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 CDJ83649.1 - 2.8e-14 53.2 0.6 1.7e-06 28.3 0.3 2.8 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 CDJ83649.1 - 2.9e-12 46.6 0.0 1.2e-05 25.4 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin domain Laminin_EGF PF00053.24 CDJ83649.1 - 3e-12 46.5 33.9 1e-06 28.7 8.3 6.4 5 1 1 6 6 6 3 Laminin EGF domain V-set PF07686.17 CDJ83649.1 - 2.9e-08 33.9 0.3 0.021 15.0 0.0 4.1 2 2 2 4 4 4 2 Immunoglobulin V-set domain Izumo-Ig PF16706.5 CDJ83649.1 - 0.033 14.3 0.1 13 5.9 0.0 2.7 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain MBOAT PF03062.19 CDJ83650.1 - 7.2e-09 35.5 32.7 1.1e-08 34.9 28.5 2.2 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Ldl_recept_a PF00057.18 CDJ83651.1 - 1.6e-25 89.0 56.6 5.8e-12 45.6 11.0 4.2 4 0 0 4 4 4 3 Low-density lipoprotein receptor domain class A I-set PF07679.16 CDJ83651.1 - 3.7e-07 30.1 0.0 8.9e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ83651.1 - 1.6e-06 28.6 0.2 6.8e-06 26.6 0.0 2.1 3 0 0 3 3 3 1 Immunoglobulin domain MCPVI PF02993.14 CDJ83652.1 - 0.0072 16.2 0.0 0.0085 15.9 0.0 1.0 1 0 0 1 1 1 1 Minor capsid protein VI FDX-ACB PF03147.14 CDJ83652.1 - 0.029 14.8 0.0 0.063 13.7 0.0 1.6 1 1 1 2 2 2 0 Ferredoxin-fold anticodon binding domain EGF_2 PF07974.13 CDJ83653.1 - 1.4e-06 28.6 2.7 3.9e-06 27.1 2.7 1.8 1 0 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.24 CDJ83653.1 - 0.0011 19.0 0.7 0.0011 19.0 0.7 1.8 2 0 0 2 2 2 1 Laminin EGF domain I-EGF_1 PF18372.1 CDJ83653.1 - 0.0021 18.1 0.3 0.0067 16.5 0.3 1.9 1 0 0 1 1 1 1 Integrin beta epidermal growth factor like domain 1 LPMO_10 PF03067.15 CDJ83653.1 - 0.091 13.4 0.1 1.8 9.2 0.0 2.8 2 1 1 3 3 3 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading EGF_Tenascin PF18720.1 CDJ83653.1 - 1.3 9.2 4.8 0.96 9.6 2.6 2.0 2 0 0 2 2 2 0 Tenascin EGF domain PBD PF00786.28 CDJ83654.1 - 0.078 13.4 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 P21-Rho-binding domain Helicase_C PF00271.31 CDJ83655.1 - 6.8e-30 103.7 1.0 9.9e-30 103.2 1.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CDJ83655.1 - 0.00072 18.8 0.2 0.00095 18.4 0.2 1.1 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Fringe PF02434.16 CDJ83656.1 - 2.6e-14 53.3 0.6 1.4e-13 50.9 0.6 1.9 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 CDJ83656.1 - 0.00035 20.5 0.1 0.033 14.0 0.2 2.3 1 1 1 2 2 2 2 Galactosyltransferase FGGY_N PF00370.21 CDJ83657.1 - 0.0015 18.1 0.5 0.0065 16.1 0.5 1.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Peptidase_M20 PF01546.28 CDJ83658.1 - 6.9e-33 114.1 0.0 8.4e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CDJ83658.1 - 5.8e-13 48.7 0.0 9e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CDJ83658.1 - 0.0063 16.2 0.0 0.022 14.4 0.0 1.9 2 1 0 2 2 2 1 Peptidase family M28 CARM1 PF11531.8 CDJ83659.1 - 0.057 13.6 1.4 0.072 13.3 0.6 1.5 1 1 1 2 2 2 0 Coactivator-associated arginine methyltransferase 1 N terminal VWC PF00093.18 CDJ83660.1 - 1e-29 102.6 137.4 7.1e-10 39.0 17.5 13.8 9 2 3 12 12 12 6 von Willebrand factor type C domain Antistasin PF02822.14 CDJ83660.1 - 4.4e-12 46.4 41.8 1.5e-06 28.7 7.8 14.9 18 3 0 18 18 18 3 Antistasin family IGFBP PF00219.18 CDJ83660.1 - 1.1e-07 32.4 25.9 1.1e-07 32.4 25.9 14.7 5 4 8 13 13 13 1 Insulin-like growth factor binding protein TILa PF12714.7 CDJ83660.1 - 9.8e-06 25.4 22.7 4.1e-05 23.4 7.5 13.9 14 3 2 16 16 16 5 TILa domain PSP94 PF05825.11 CDJ83660.1 - 0.0084 16.7 5.1 0.0084 16.7 5.1 9.2 5 3 5 10 10 10 2 Beta-microseminoprotein (PSP-94) Lectin_C PF00059.21 CDJ83661.1 - 6e-18 65.5 0.3 1.2e-17 64.6 0.1 1.6 2 0 0 2 2 2 1 Lectin C-type domain Filament PF00038.21 CDJ83661.1 - 0.003 17.2 0.2 0.0051 16.4 0.2 1.3 1 0 0 1 1 1 1 Intermediate filament protein GLE1 PF07817.13 CDJ83661.1 - 0.073 12.3 0.1 0.36 10.0 0.1 1.9 1 1 1 2 2 2 0 GLE1-like protein BBP1_C PF15272.6 CDJ83661.1 - 0.12 12.2 5.2 0.24 11.2 5.2 1.5 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Phasin PF05597.11 CDJ83661.1 - 0.15 12.0 0.1 0.27 11.2 0.1 1.4 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) GlcNAc-1_reg PF18440.1 CDJ83661.1 - 0.17 12.1 0.2 0.29 11.4 0.2 1.3 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain IBR PF01485.21 CDJ83662.1 - 5.3e-14 52.2 22.8 1.7e-09 37.8 4.0 3.1 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain RWD PF05773.22 CDJ83662.1 - 7.7e-12 45.5 0.5 1.7e-11 44.4 0.5 1.6 1 0 0 1 1 1 1 RWD domain IBR PF01485.21 CDJ83663.1 - 8e-18 64.4 38.5 2.5e-10 40.4 2.3 3.9 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain RWD PF05773.22 CDJ83663.1 - 1.5e-11 44.6 0.0 3e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-C3HC4 PF00097.25 CDJ83663.1 - 7.1e-05 22.6 5.9 7.1e-05 22.6 5.9 4.1 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ83663.1 - 0.00043 20.6 6.5 0.00043 20.6 6.5 4.5 3 1 1 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 CDJ83663.1 - 0.00056 19.9 7.1 0.00056 19.9 7.1 3.5 3 0 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDJ83663.1 - 0.00097 18.9 5.0 0.00097 18.9 5.0 4.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ83663.1 - 0.0021 18.0 9.7 0.0021 18.0 9.7 3.9 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_11 PF17123.5 CDJ83663.1 - 0.015 15.0 7.3 0.06 13.1 7.3 2.2 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 CDJ83663.1 - 0.034 14.3 2.6 0.034 14.3 2.6 5.1 5 1 0 5 5 5 0 zinc finger of C3HC4-type, RING DUF2828 PF11443.8 CDJ83664.1 - 0.021 13.0 1.7 0.021 13.0 1.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) E7 PF00527.18 CDJ83664.1 - 0.65 10.2 6.5 1.6 9.0 6.4 1.8 1 1 0 1 1 1 0 E7 protein, Early protein Peroxin-3 PF04882.12 CDJ83665.1 - 0.0021 17.1 4.1 0.0034 16.5 4.1 1.2 1 0 0 1 1 1 1 Peroxin-3 ETRAMP PF09716.10 CDJ83665.1 - 0.0031 17.6 0.0 0.013 15.5 0.0 2.0 1 1 1 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) DUF2207 PF09972.9 CDJ83665.1 - 0.0034 16.2 0.0 0.0052 15.6 0.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 CDJ83665.1 - 0.0049 16.8 8.9 0.0049 16.8 8.9 2.5 1 1 1 2 2 2 1 TMEM154 protein family Tmemb_9 PF05434.11 CDJ83665.1 - 0.0097 15.8 0.3 0.023 14.6 0.3 1.7 1 0 0 1 1 1 1 TMEM9 DUF4834 PF16118.5 CDJ83665.1 - 0.016 16.2 7.2 0.016 16.2 7.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) DUF2254 PF10011.9 CDJ83665.1 - 0.019 13.8 0.2 0.029 13.2 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF4484 PF14831.6 CDJ83665.1 - 0.03 14.4 0.8 0.053 13.6 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) DUF3328 PF11807.8 CDJ83665.1 - 0.033 14.0 0.3 0.07 12.9 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DUF5305 PF17231.2 CDJ83665.1 - 0.034 13.5 2.3 0.056 12.8 2.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) G0-G1_switch_2 PF15103.6 CDJ83665.1 - 0.046 14.2 0.6 0.13 12.7 0.6 1.7 1 0 0 1 1 1 0 G0/G1 switch protein 2 Claudin_2 PF13903.6 CDJ83665.1 - 0.07 12.9 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Baculo_11_kDa PF06143.11 CDJ83665.1 - 0.14 11.8 0.9 0.33 10.5 0.9 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family EphA2_TM PF14575.6 CDJ83665.1 - 0.17 12.8 1.0 0.53 11.2 1.0 2.0 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Hid1 PF12722.7 CDJ83665.1 - 0.27 9.3 6.3 0.32 9.1 6.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein tRNA_anti-like PF12869.7 CDJ83665.1 - 0.27 10.8 4.3 0.47 10.1 0.5 2.4 2 0 0 2 2 2 0 tRNA_anti-like DUF2561 PF10812.8 CDJ83665.1 - 0.37 10.8 3.4 0.23 11.5 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2561) FAM176 PF14851.6 CDJ83665.1 - 0.53 9.9 5.0 1.1 9.0 1.9 2.7 1 1 1 2 2 2 0 FAM176 family DUF2614 PF11023.8 CDJ83665.1 - 0.54 10.4 3.3 19 5.4 0.1 2.3 2 0 0 2 2 2 0 Zinc-ribbon containing domain SIT PF15330.6 CDJ83665.1 - 0.66 10.4 5.6 1.8 9.0 2.3 2.9 2 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT LRRC37AB_C PF14914.6 CDJ83665.1 - 0.97 9.3 9.1 0.31 10.9 1.0 2.3 1 1 1 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Rtf2 PF04641.12 CDJ83665.1 - 5.8 6.2 8.8 10 5.4 8.8 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger SRP-alpha_N PF04086.13 CDJ83665.1 - 6.3 6.6 15.2 11 5.8 15.2 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Astacin PF01400.24 CDJ83666.1 - 2.7e-63 213.1 0.1 4.5e-63 212.3 0.1 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 CDJ83666.1 - 0.00072 19.4 2.8 0.011 15.5 0.4 2.2 1 1 1 2 2 2 1 Matrixin Reprolysin_4 PF13583.6 CDJ83666.1 - 0.0012 18.6 0.1 0.002 17.8 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like CUB PF00431.20 CDJ83666.1 - 0.0018 18.6 0.0 0.0037 17.6 0.0 1.5 1 0 0 1 1 1 1 CUB domain Reprolysin_3 PF13582.6 CDJ83666.1 - 0.12 12.9 0.0 0.32 11.5 0.0 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Cyclin PF08613.11 CDJ83667.1 - 6.3e-09 36.4 0.0 9.9e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CDJ83667.1 - 4.1e-06 26.6 0.0 7.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain PAN_1 PF00024.26 CDJ83668.1 - 3.9e-14 52.4 18.7 0.0013 18.7 0.2 5.3 3 2 1 4 4 4 4 PAN domain Nse5 PF08691.10 CDJ83668.1 - 0.0088 14.8 0.3 1.2 7.7 0.0 2.3 2 0 0 2 2 2 2 DNA repair proteins Nse5 and Nse6 Ribosomal_60s PF00428.19 CDJ83670.1 - 1e-23 83.7 7.9 1.3e-23 83.4 7.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein PrmA PF06325.13 CDJ83671.1 - 1.9e-09 37.3 0.2 2.7e-09 36.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 CDJ83671.1 - 5.9e-07 29.5 0.0 6.5e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 CDJ83671.1 - 7.6e-07 29.0 0.0 8.7e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 CDJ83671.1 - 9.5e-06 25.3 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CDJ83671.1 - 1.8e-05 25.3 0.0 4.9e-05 24.0 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ83671.1 - 0.00013 22.6 0.1 0.00024 21.8 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ83671.1 - 0.00069 19.4 0.0 0.0007 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ83671.1 - 0.00082 20.0 0.1 0.006 17.2 0.1 2.0 1 1 1 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 CDJ83671.1 - 0.0054 16.5 0.0 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_15 PF09445.10 CDJ83671.1 - 0.0069 16.0 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase DUF2195 PF09961.9 CDJ83671.1 - 0.057 13.4 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2195) TehB PF03848.14 CDJ83671.1 - 0.069 12.6 0.0 0.085 12.3 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB HyaE PF07449.11 CDJ83671.1 - 0.095 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE YtfJ_HI0045 PF09695.10 CDJ83671.1 - 0.14 11.8 0.1 0.21 11.2 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (YtfJ_HI0045) Cyclin_N PF00134.23 CDJ83672.1 - 4.8e-37 126.5 0.1 9.3e-37 125.6 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CDJ83672.1 - 2.5e-05 24.3 0.0 0.00013 22.1 0.0 2.2 3 0 0 3 3 3 1 Cyclin, C-terminal domain Ashwin PF15323.6 CDJ83672.1 - 0.0024 17.9 1.5 0.0045 17.0 1.5 1.4 1 0 0 1 1 1 1 Developmental protein Guanylate_kin PF00625.21 CDJ83674.1 - 3.4e-52 176.8 0.2 6e-52 176.0 0.2 1.4 2 0 0 2 2 2 1 Guanylate kinase VGCC_beta4Aa_N PF12052.8 CDJ83674.1 - 6.3e-18 64.6 3.8 1.5e-17 63.4 3.8 1.7 1 0 0 1 1 1 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal SH3_1 PF00018.28 CDJ83674.1 - 0.0043 16.6 0.1 0.0096 15.5 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDJ83674.1 - 0.058 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Variant SH3 domain UPF0524 PF15823.5 CDJ83675.1 - 0.2 11.0 2.4 0.34 10.3 2.4 1.3 1 0 0 1 1 1 0 UPF0524 of C3orf70 Asp PF00026.23 CDJ83676.1 - 2.7e-13 50.0 0.1 3.5e-13 49.7 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ83676.1 - 3e-06 27.6 0.1 3.8e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal ODV-E18 PF10717.9 CDJ83677.1 - 0.11 12.4 1.5 0.21 11.5 1.5 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 ASFV_J13L PF05568.11 CDJ83677.1 - 0.41 10.4 2.2 0.71 9.6 2.2 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Ca_hom_mod PF14798.6 CDJ83678.1 - 8.9e-35 120.0 1.6 1.5e-34 119.2 1.6 1.3 1 0 0 1 1 1 1 Calcium homeostasis modulator Bromodomain PF00439.25 CDJ83678.1 - 8.8e-14 51.3 0.0 2e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Tmemb_9 PF05434.11 CDJ83678.1 - 0.01 15.8 0.0 0.027 14.3 0.0 1.7 1 0 0 1 1 1 1 TMEM9 AT_hook PF02178.19 CDJ83678.1 - 0.18 11.7 6.6 0.68 10.0 6.6 2.1 1 0 0 1 1 1 0 AT hook motif Polo_box_2 PF18531.1 CDJ83679.1 - 2.2e-51 172.7 0.0 4.4e-51 171.7 0.0 1.5 1 0 0 1 1 1 1 Polo box domain Polo_box_3 PF18544.1 CDJ83679.1 - 5.6e-39 132.7 0.4 1.4e-38 131.5 0.4 1.7 1 0 0 1 1 1 1 Polo box domain Pkinase PF00069.25 CDJ83679.1 - 5.5e-35 121.0 0.0 1.4e-33 116.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ83679.1 - 3.1e-22 79.1 0.0 5.8e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ83679.1 - 1.4e-06 27.4 0.0 2.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDJ83679.1 - 0.0023 17.3 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDJ83679.1 - 0.085 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 CDJ83680.1 - 4.2e-07 29.6 0.0 4.8e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ83680.1 - 0.017 14.4 0.0 0.019 14.3 0.0 1.0 1 0 0 1 1 1 0 Protein tyrosine kinase CCDC53 PF10152.9 CDJ83681.1 - 1.1e-35 123.3 0.4 1.1e-35 123.3 0.4 1.4 2 0 0 2 2 2 1 Subunit CCDC53 of WASH complex Cas_GSU0053 PF09617.10 CDJ83681.1 - 0.1 12.5 0.2 0.14 12.1 0.2 1.2 1 0 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) LOH1CR12 PF10158.9 CDJ83682.1 - 7.1e-36 123.1 0.7 1e-35 122.7 0.7 1.2 1 0 0 1 1 1 1 Tumour suppressor protein NPV_P10 PF05531.12 CDJ83682.1 - 0.011 16.2 2.1 0.024 15.1 2.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Sec34 PF04136.15 CDJ83682.1 - 0.056 13.3 0.3 0.084 12.8 0.3 1.2 1 0 0 1 1 1 0 Sec34-like family IZUMO PF15005.6 CDJ83682.1 - 0.14 12.7 0.1 7.8 7.0 0.0 2.1 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated ANAPC4 PF12896.7 CDJ83682.1 - 0.15 11.5 0.9 0.38 10.2 0.7 1.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 Apc13p PF05839.11 CDJ83683.1 - 0.00027 21.1 0.7 0.00034 20.7 0.7 1.3 1 1 0 1 1 1 1 Apc13p protein Acetyltransf_1 PF00583.25 CDJ83684.1 - 1.2e-21 77.1 0.1 3e-10 40.3 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDJ83684.1 - 2.1e-12 47.1 0.0 4.7e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDJ83684.1 - 8.5e-11 42.1 0.6 0.00038 20.8 0.1 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CDJ83684.1 - 0.041 14.0 0.2 12 6.1 0.0 2.3 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase PRC PF05239.16 CDJ83684.1 - 0.078 13.1 4.7 3.4 7.8 0.2 3.9 2 2 1 3 3 3 0 PRC-barrel domain AstA PF04958.12 CDJ83684.1 - 0.16 10.5 0.1 6.2 5.3 0.0 2.6 3 0 0 3 3 3 0 Arginine N-succinyltransferase beta subunit IF-2B PF01008.17 CDJ83684.1 - 0.18 11.0 0.0 5.8 6.0 0.0 2.1 2 0 0 2 2 2 0 Initiation factor 2 subunit family C4bp_oligo PF18453.1 CDJ83684.1 - 0.18 12.0 2.1 9.8 6.5 0.1 2.4 2 0 0 2 2 2 0 Oligomerization domain of C4b-binding protein alpha DHR-2 PF06920.13 CDJ83685.1 - 1.3e-78 265.0 4.2 4.9e-75 253.2 1.8 2.3 1 1 1 2 2 2 2 Dock homology region 2 DOCK-C2 PF14429.6 CDJ83685.1 - 2.2e-41 141.8 0.0 4.1e-41 140.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 CDJ83685.1 - 4.7e-16 59.2 1.7 6.7e-16 58.7 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3398) DOCK_N PF16172.5 CDJ83685.1 - 0.0069 15.3 0.2 0.15 11.0 0.0 2.5 2 0 0 2 2 2 1 DOCK N-terminus PAF-AH_p_II PF03403.13 CDJ83686.1 - 0.03 12.8 0.2 0.036 12.6 0.2 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DDDD PF10161.9 CDJ83687.1 - 0.96 9.3 5.3 1.7 8.4 0.0 3.0 3 0 0 3 3 3 0 Putative mitochondrial precursor protein DUF2097 PF09870.9 CDJ83688.1 - 0.073 13.3 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2097) B2-adapt-app_C PF09066.10 CDJ83688.1 - 0.091 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain PKD_channel PF08016.12 CDJ83689.1 - 3.9e-66 223.5 27.2 1.7e-65 221.4 27.2 2.0 1 1 0 1 1 1 1 Polycystin cation channel PLAT PF01477.23 CDJ83689.1 - 7.7e-12 45.8 0.0 3.3e-11 43.8 0.0 2.0 2 0 0 2 2 2 1 PLAT/LH2 domain Ion_trans PF00520.31 CDJ83689.1 - 0.42 9.8 36.7 0.013 14.7 27.4 2.8 3 0 0 3 3 3 0 Ion transport protein DUF3719 PF12516.8 CDJ83690.1 - 9.5e-05 22.0 0.0 0.0002 21.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3719) tRNA-synt_2b PF00587.25 CDJ83691.1 - 1.5e-40 139.1 0.0 2.5e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CDJ83691.1 - 6.5e-18 65.0 10.4 8.2e-18 64.6 2.5 2.7 2 1 1 3 3 3 2 Seryl-tRNA synthetase N-terminal domain Prok-TraM PF09228.10 CDJ83691.1 - 0.051 13.9 0.5 0.12 12.8 0.5 1.6 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM Pkinase PF00069.25 CDJ83693.1 - 6.6e-67 225.6 0.0 7.8e-67 225.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ83693.1 - 5.3e-32 111.1 0.0 6.5e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CDJ83693.1 - 0.039 13.6 0.1 2.6 7.6 0.0 2.7 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF3629 PF12302.8 CDJ83697.1 - 0.047 13.1 0.1 0.077 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) M PF02370.16 CDJ83697.1 - 1.7 9.4 6.0 1.5 9.7 0.2 3.2 3 0 0 3 3 3 0 M protein repeat Epiglycanin_TR PF05647.11 CDJ83699.1 - 4.2 7.4 14.7 8.7 6.4 14.7 1.5 1 0 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like MgtE PF01769.16 CDJ83700.1 - 3.3e-28 98.6 21.4 6.8e-18 65.2 2.2 3.0 3 0 0 3 3 3 2 Divalent cation transporter Cation_efflux PF01545.21 CDJ83701.1 - 1.2e-24 87.2 13.1 1.5e-24 86.9 13.1 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 CDJ83701.1 - 2.3e-07 30.8 0.3 4.6e-07 29.9 0.3 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Cation_efflux PF01545.21 CDJ83702.1 - 9.9e-27 94.0 14.2 1.3e-26 93.6 14.2 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 CDJ83702.1 - 0.013 15.6 0.4 0.025 14.7 0.4 1.5 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter Vps52 PF04129.12 CDJ83703.1 - 8e-143 476.8 8.4 1.3e-142 476.2 8.4 1.3 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 CDJ83703.1 - 0.00041 18.9 7.5 0.00041 18.9 7.5 2.5 3 0 0 3 3 3 1 Exocyst complex component Sec3 ApoLp-III PF07464.11 CDJ83703.1 - 0.014 15.5 1.8 0.49 10.5 0.8 2.9 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) E2F_TDP PF02319.20 CDJ83703.1 - 0.082 13.0 0.4 0.79 9.8 0.2 2.9 3 1 0 3 3 3 0 E2F/DP family winged-helix DNA-binding domain Rpn3_C PF08375.11 CDJ83703.1 - 0.52 10.8 2.8 0.71 10.3 0.0 2.6 3 0 0 3 3 3 0 Proteasome regulatory subunit C-terminal Death PF00531.22 CDJ83704.1 - 0.0014 18.7 0.0 0.0033 17.5 0.0 1.6 1 0 0 1 1 1 1 Death domain RICH PF05062.12 CDJ83704.1 - 0.023 15.1 0.1 0.049 14.0 0.1 1.5 1 0 0 1 1 1 0 RICH domain Cation_efflux PF01545.21 CDJ83705.1 - 3.3e-48 164.1 1.9 4.2e-48 163.7 1.9 1.1 1 0 0 1 1 1 1 Cation efflux family PTPS_related PF10131.9 CDJ83705.1 - 7 4.8 6.6 13 4.0 6.6 1.3 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein FHA PF00498.26 CDJ83706.1 - 1.7e-15 57.1 0.0 5.6e-15 55.4 0.0 1.9 2 0 0 2 2 2 1 FHA domain Pox_A_type_inc PF04508.12 CDJ83706.1 - 1.5e-06 27.7 5.7 0.04 13.8 0.0 4.1 3 0 0 3 3 3 2 Viral A-type inclusion protein repeat Yop-YscD_cpl PF16697.5 CDJ83706.1 - 0.0002 21.6 0.0 0.0013 19.0 0.0 2.3 3 0 0 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain Syntaxin_2 PF14523.6 CDJ83706.1 - 0.41 11.0 3.9 0.65 10.4 0.3 2.5 1 1 0 2 2 2 0 Syntaxin-like protein XhlA PF10779.9 CDJ83706.1 - 3.1 8.1 9.4 3.5 7.9 0.8 3.7 2 1 1 3 3 3 0 Haemolysin XhlA Snapin_Pallidin PF14712.6 CDJ83706.1 - 4.1 7.9 14.6 0.27 11.7 0.6 3.6 1 1 1 3 3 3 0 Snapin/Pallidin DUF1664 PF07889.12 CDJ83706.1 - 5.2 7.1 6.2 3.3 7.8 0.5 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) IFP_35_N PF07334.13 CDJ83706.1 - 5.7 7.1 5.8 36 4.5 0.2 3.2 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Fib_alpha PF08702.10 CDJ83706.1 - 6.3 7.0 9.6 1.1 9.4 3.5 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family ATG16 PF08614.11 CDJ83706.1 - 8.2 6.6 29.8 2 8.6 0.0 3.2 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) WAPL PF07814.13 CDJ83708.1 - 4.5e-79 265.9 15.0 6.3e-79 265.4 15.0 1.2 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Histone PF00125.24 CDJ83709.1 - 5.2e-18 65.7 0.0 7.3e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CDJ83709.1 - 4e-12 45.6 0.0 8.3e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CDJ83709.1 - 0.002 18.4 0.0 0.0033 17.7 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CDC50 PF03381.15 CDJ83710.1 - 5.4e-87 291.8 0.0 6.8e-87 291.5 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Glypican PF01153.19 CDJ83711.1 - 2.1e-96 324.0 1.8 2.7e-96 323.6 1.8 1.0 1 0 0 1 1 1 1 Glypican Fz PF01392.22 CDJ83711.1 - 0.011 16.3 0.8 0.036 14.7 0.8 1.8 1 0 0 1 1 1 0 Fz domain Tudor-knot PF11717.8 CDJ83713.1 - 6.2e-12 45.2 0.7 1.5e-11 44.0 0.7 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 CDJ83713.1 - 0.0046 16.8 0.4 0.011 15.6 0.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain GDP_Man_Dehyd PF16363.5 CDJ83714.1 - 4.3e-158 526.0 0.0 4.9e-158 525.8 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CDJ83714.1 - 2.2e-77 259.8 0.0 2.8e-77 259.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CDJ83714.1 - 5.8e-06 25.6 0.0 1.1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CDJ83714.1 - 8e-06 25.2 0.0 1.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain UAA PF08449.11 CDJ83715.1 - 1.7e-68 231.0 14.3 2.1e-68 230.8 14.3 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CDJ83715.1 - 0.43 10.8 22.3 0.037 14.2 11.5 2.6 2 1 0 2 2 2 0 EamA-like transporter family DUF4228 PF14009.6 CDJ83717.1 - 6.3 7.2 11.4 0.76 10.2 2.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4228) C1_1 PF00130.22 CDJ83718.1 - 0.0061 16.4 12.5 0.012 15.5 12.5 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Collagen PF01391.18 CDJ83719.1 - 4.5e-22 77.6 123.2 1.8e-09 37.2 38.8 4.6 2 2 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ83719.1 - 3.2e-13 49.5 0.1 4.4e-13 49.1 0.1 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain PDZ_6 PF17820.1 CDJ83720.1 - 5e-09 35.9 0.1 1.3e-08 34.5 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CDJ83720.1 - 3.4e-05 24.1 0.0 7.8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ83720.1 - 9.9e-05 22.6 0.0 0.00021 21.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Thioredoxin_7 PF13899.6 CDJ83722.1 - 1.9e-14 53.6 0.1 4.5e-14 52.4 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin-like Thioredox_DsbH PF03190.15 CDJ83722.1 - 3.4e-09 36.9 0.2 6.7e-09 35.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 AhpC-TSA PF00578.21 CDJ83722.1 - 0.00014 21.7 0.1 0.00027 20.9 0.1 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 CDJ83722.1 - 0.0013 19.2 0.2 0.0013 19.2 0.2 2.3 1 1 0 2 2 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CDJ83722.1 - 0.0021 18.3 0.2 0.77 10.1 0.1 2.9 1 1 1 2 2 2 2 Thioredoxin-like Paf1 PF03985.13 CDJ83722.1 - 0.024 13.7 30.6 0.036 13.1 30.6 1.3 1 0 0 1 1 1 0 Paf1 SAPS PF04499.15 CDJ83722.1 - 0.35 9.6 12.9 0.34 9.6 12.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 CDJ83722.1 - 0.39 10.5 31.1 0.53 10.1 31.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.12 CDJ83722.1 - 0.57 10.4 17.9 0.67 10.2 17.9 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Hid1 PF12722.7 CDJ83722.1 - 0.68 8.0 11.0 0.66 8.0 11.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDHD PF02862.17 CDJ83722.1 - 1.1 9.3 11.0 2 8.5 11.0 1.5 1 0 0 1 1 1 0 DDHD domain SID-1_RNA_chan PF13965.6 CDJ83722.1 - 4 5.7 6.8 5 5.4 6.8 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 S1-like PF14444.6 CDJ83723.1 - 3.6e-31 106.9 2.0 5.5e-31 106.3 0.8 2.0 2 0 0 2 2 2 1 S1-like DBC1 PF14443.6 CDJ83723.1 - 5e-27 94.3 0.0 1.4e-26 92.9 0.0 1.8 1 0 0 1 1 1 1 DBC1 SAP PF02037.27 CDJ83723.1 - 5.9e-10 38.7 1.1 5.9e-10 38.7 1.1 2.5 3 0 0 3 3 3 1 SAP domain EF-hand_7 PF13499.6 CDJ83723.1 - 0.0074 16.7 0.1 0.027 14.9 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair Lectin_N PF03954.14 CDJ83723.1 - 3.3 7.5 5.4 12 5.6 2.1 2.8 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Eapp_C PF10238.9 CDJ83723.1 - 4.1 7.5 14.8 1.3 9.1 1.4 3.0 2 0 0 2 2 2 0 E2F-associated phosphoprotein TRAP_alpha PF03896.16 CDJ83723.1 - 7.7 5.6 15.6 3.9 6.6 2.5 2.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit zf-CpG_bind_C PF12269.8 CDJ83724.1 - 5.4e-53 180.2 3.7 7.1e-53 179.8 3.7 1.2 1 0 0 1 1 1 1 CpG binding protein zinc finger C terminal domain zf-CXXC PF02008.20 CDJ83724.1 - 0.41 10.7 25.9 0.067 13.2 19.0 3.0 2 1 0 2 2 2 0 CXXC zinc finger domain PMM PF03332.13 CDJ83725.1 - 6.9e-100 333.3 0.7 8.1e-100 333.1 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 CDJ83725.1 - 0.00016 21.5 0.0 0.00075 19.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CDJ83725.1 - 0.0025 17.4 0.0 0.092 12.3 0.0 2.0 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase DUF5128 PF17170.4 CDJ83725.1 - 0.026 13.7 0.1 0.045 12.9 0.1 1.3 1 0 0 1 1 1 0 6-bladed beta-propeller ATP-synt_C PF00137.21 CDJ83726.1 - 3e-35 120.3 35.3 2.7e-22 78.9 13.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CrgA PF06781.12 CDJ83726.1 - 0.25 11.4 3.0 0.59 10.2 0.5 2.2 2 0 0 2 2 2 0 Cell division protein CrgA DUF2970 PF11174.8 CDJ83726.1 - 2.6 7.9 7.9 0.66 9.9 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) V-ATPase_C PF03223.15 CDJ83727.1 - 2.8e-55 188.2 1.6 3.1e-55 188.1 1.6 1.0 1 0 0 1 1 1 1 V-ATPase subunit C GAT PF03127.14 CDJ83727.1 - 0.013 15.8 1.4 0.13 12.6 0.1 2.4 2 1 0 2 2 2 0 GAT domain UFC1 PF08694.11 CDJ83728.1 - 4e-76 253.9 0.1 4.7e-76 253.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 SLATT_5 PF18160.1 CDJ83728.1 - 0.0042 16.4 0.8 0.0057 16.0 0.1 1.5 2 0 0 2 2 2 1 SMODS and SLOG-associating 2TM effector domain family 5 RWD PF05773.22 CDJ83728.1 - 0.011 16.0 0.0 0.015 15.6 0.0 1.2 1 0 0 1 1 1 0 RWD domain UQ_con PF00179.26 CDJ83728.1 - 0.023 14.4 0.1 0.036 13.7 0.1 1.4 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme Mre11_DNA_bind PF04152.14 CDJ83729.1 - 2.6e-23 83.2 0.0 6.1e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 CDJ83729.1 - 2.1e-13 51.3 0.9 3.3e-13 50.6 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDJ83729.1 - 4.6e-07 30.2 0.0 3.5e-06 27.3 0.0 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Hormone_recep PF00104.30 CDJ83730.1 - 4.3e-05 23.2 0.0 0.0051 16.4 0.1 2.1 2 0 0 2 2 2 2 Ligand-binding domain of nuclear hormone receptor RhoGAP PF00620.27 CDJ83731.1 - 5e-36 123.8 0.0 1.2e-35 122.6 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain RhoGAP-FF1 PF16512.5 CDJ83731.1 - 3.9e-06 27.4 0.2 0.00045 20.8 0.0 3.6 3 0 0 3 3 3 1 p190-A and -B Rho GAPs FF domain Ras PF00071.22 CDJ83731.1 - 0.00028 20.5 0.1 0.17 11.5 0.0 2.4 2 0 0 2 2 2 2 Ras family GTP_EFTU PF00009.27 CDJ83731.1 - 0.034 13.7 0.3 0.067 12.7 0.3 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain NOG1 PF06858.14 CDJ83731.1 - 0.058 13.2 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) Arf PF00025.21 CDJ83731.1 - 0.13 11.7 0.3 0.26 10.7 0.3 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_16 PF13191.6 CDJ83731.1 - 0.37 11.1 1.8 4.5 7.6 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain RVT_1 PF00078.27 CDJ83732.1 - 3e-43 147.9 0.0 4.3e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YlmH_RBD PF17774.1 CDJ83732.1 - 0.069 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Putative RNA-binding domain in YlmH HMG_box PF00505.19 CDJ83733.1 - 2e-25 89.0 2.1 3.1e-25 88.4 2.1 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ83733.1 - 1.4e-10 41.6 1.1 2.6e-10 40.7 1.1 1.4 1 0 0 1 1 1 1 HMG-box domain SOXp PF12336.8 CDJ83733.1 - 0.045 14.8 5.0 0.16 13.1 4.9 2.1 1 1 0 1 1 1 0 SOX transcription factor Neur_chan_memb PF02932.16 CDJ83734.1 - 2e-33 116.4 0.3 1.2e-30 107.4 0.1 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CDJ83734.1 - 0.041 13.3 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel ligand binding domain Thymidylat_synt PF00303.19 CDJ83734.1 - 0.17 11.0 0.2 0.38 9.8 0.1 1.6 2 0 0 2 2 2 0 Thymidylate synthase Nuc_sug_transp PF04142.15 CDJ83739.1 - 4.3e-118 394.0 21.1 5e-118 393.8 21.1 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CDJ83739.1 - 4.1e-07 30.2 29.8 9.1e-07 29.1 2.8 2.5 3 0 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 CDJ83739.1 - 0.0018 17.5 13.4 0.0018 17.5 13.4 1.4 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport PrgI PF12666.7 CDJ83739.1 - 0.016 15.9 9.2 1.9 9.2 2.6 3.3 2 1 0 2 2 2 0 PrgI family protein DUF3325 PF11804.8 CDJ83739.1 - 3.6 7.8 6.1 0.44 10.7 0.3 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3325) 7tm_1 PF00001.21 CDJ83740.1 - 7.3e-17 61.6 18.4 7.3e-17 61.6 18.4 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CDJ83740.1 - 4.5e-07 29.8 10.5 4.5e-07 29.8 10.5 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF1980 PF09323.10 CDJ83740.1 - 0.92 9.4 4.5 0.17 11.8 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) SIS PF01380.22 CDJ83743.1 - 2.1e-53 179.7 0.4 1.7e-31 108.8 0.0 2.9 3 0 0 3 3 3 2 SIS domain GATase_6 PF13522.6 CDJ83743.1 - 3.3e-20 72.7 0.0 7.4e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CDJ83743.1 - 1.2e-14 54.3 0.0 3.5e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CDJ83743.1 - 5e-05 22.3 0.1 0.0001 21.3 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 CDJ83743.1 - 0.012 15.6 0.0 0.035 14.1 0.0 1.8 2 0 0 2 2 2 0 SIS domain Swi3 PF07962.12 CDJ83743.1 - 0.072 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 GATase_2 PF00310.21 CDJ83743.1 - 0.11 11.2 0.2 0.23 10.1 0.2 1.4 1 0 0 1 1 1 0 Glutamine amidotransferases class-II Acyl-thio_N PF12590.8 CDJ83744.1 - 0.17 12.5 0.8 0.29 11.7 0.8 1.4 1 0 0 1 1 1 0 Acyl-ATP thioesterase MBOAT PF03062.19 CDJ83745.1 - 3.2e-09 36.6 17.2 6e-09 35.7 17.2 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Ribosomal_S13 PF00416.22 CDJ83746.1 - 1.2e-52 177.6 0.3 1.4e-52 177.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 PP28 PF10252.9 CDJ83746.1 - 0.034 14.6 0.6 0.058 13.8 0.6 1.4 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 SecY PF00344.20 CDJ83747.1 - 2.1e-76 257.1 10.7 2.7e-76 256.8 10.7 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CDJ83747.1 - 4e-18 65.0 1.6 8.1e-18 64.0 0.1 2.4 2 0 0 2 2 2 1 Plug domain of Sec61p DUF2975 PF11188.8 CDJ83747.1 - 6.2 6.7 10.1 0.63 9.9 2.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) 7tm_1 PF00001.21 CDJ83748.1 - 1.7e-10 40.7 0.2 1.7e-10 40.7 0.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RibD_C PF01872.17 CDJ83748.1 - 0.043 13.6 0.0 0.052 13.4 0.0 1.1 1 0 0 1 1 1 0 RibD C-terminal domain Vg_Tdu PF07545.14 CDJ83749.1 - 0.035 13.9 4.2 2.6 7.9 1.2 2.5 2 0 0 2 2 2 0 Vestigial/Tondu family EGF_CA PF07645.15 CDJ83750.1 - 2.8e-38 129.8 148.7 1.6e-10 41.0 9.0 10.8 10 2 0 10 10 10 6 Calcium-binding EGF domain EGF_3 PF12947.7 CDJ83750.1 - 8.6e-23 80.2 109.6 2e-08 34.3 2.4 10.2 9 2 1 10 10 10 6 EGF domain NIDO PF06119.14 CDJ83750.1 - 8.4e-18 65.1 0.0 8.5e-10 39.4 0.0 3.2 2 1 0 2 2 2 2 Nidogen-like cEGF PF12662.7 CDJ83750.1 - 1.3e-11 44.2 89.9 0.00028 20.8 1.5 11.0 10 1 0 10 10 10 7 Complement Clr-like EGF-like hEGF PF12661.7 CDJ83750.1 - 2.7e-11 43.7 121.0 9.7e-05 22.9 3.1 12.8 12 1 0 12 12 12 8 Human growth factor-like EGF EGF PF00008.27 CDJ83750.1 - 1.8e-06 28.2 135.8 0.0085 16.4 6.8 12.6 11 1 1 12 12 12 7 EGF-like domain EGF_MSP1_1 PF12946.7 CDJ83750.1 - 1.3e-05 25.1 35.0 0.00054 19.9 6.4 10.5 11 0 0 11 11 11 4 MSP1 EGF domain 1 TMEM154 PF15102.6 CDJ83750.1 - 8.9e-05 22.4 5.6 0.00014 21.8 0.0 2.3 2 0 0 2 2 2 1 TMEM154 protein family Cpta_toxin PF07254.12 CDJ83750.1 - 0.067 13.2 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Membrane-bound toxin component of toxin-antitoxin system CTV_P6 PF06706.11 CDJ83750.1 - 1.1 9.0 3.5 0.79 9.5 1.0 2.1 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein Sugar_tr PF00083.24 CDJ83751.1 - 4.5e-28 98.3 19.7 4.5e-28 98.3 19.7 1.8 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ83751.1 - 1.4e-14 53.8 33.6 7.8e-14 51.3 33.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CDJ83751.1 - 0.0022 16.5 1.5 0.0022 16.5 1.5 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CDJ83752.1 - 2.3e-28 99.3 31.3 3.5e-28 98.7 31.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ83752.1 - 3.5e-20 72.2 39.9 1.1e-19 70.6 30.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily NAD_binding_10 PF13460.6 CDJ83753.1 - 1.4e-11 44.6 0.0 2.1e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 CDJ83753.1 - 1.1e-05 25.8 0.0 2.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 CDJ83753.1 - 0.0054 16.3 1.4 0.079 12.5 1.4 2.2 1 1 0 1 1 1 1 NmrA-like family DUF354 PF04007.12 CDJ83753.1 - 0.015 14.4 0.1 0.037 13.1 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF354) Polysacc_synt_2 PF02719.15 CDJ83753.1 - 0.015 14.4 0.3 0.14 11.2 0.3 2.1 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 CDJ83753.1 - 0.021 14.3 0.1 0.065 12.7 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HIM1 PF08732.10 CDJ83753.1 - 0.026 14.0 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 HIM1 KR PF08659.10 CDJ83753.1 - 0.053 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 CDJ83753.1 - 0.057 12.4 0.1 0.098 11.6 0.1 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CDJ83753.1 - 0.11 11.6 0.0 0.48 9.5 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein DAGK_acc PF00609.19 CDJ83755.1 - 3.3e-45 154.3 0.0 6.2e-45 153.4 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 CDJ83755.1 - 6.1e-29 100.2 0.0 1.3e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 CDJ83755.1 - 1.3e-08 34.6 18.7 1.3e-08 34.6 18.7 3.3 3 1 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DP PF08781.10 CDJ83755.1 - 0.14 12.1 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Transcription factor DP ADK_lid PF05191.14 CDJ83755.1 - 0.25 11.4 4.1 8.2 6.5 1.6 2.9 2 0 0 2 2 2 0 Adenylate kinase, active site lid PHD_4 PF16866.5 CDJ83755.1 - 1.8 8.7 15.2 0.1 12.7 5.1 2.8 2 0 0 2 2 2 0 PHD-finger ASC PF00858.24 CDJ83756.1 - 6.3e-59 200.1 6.8 9e-45 153.4 2.0 3.1 3 0 0 3 3 3 2 Amiloride-sensitive sodium channel HD_2 PF12917.7 CDJ83756.1 - 0.011 15.5 0.0 0.033 14.0 0.0 1.8 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme Mito_carr PF00153.27 CDJ83758.1 - 3e-69 229.0 1.6 1.3e-25 89.1 0.0 3.4 2 1 1 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 CDJ83758.1 - 8.7e-13 46.8 2.0 0.016 14.7 0.0 5.1 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 CDJ83758.1 - 7.5e-12 45.5 8.7 2.7e-05 24.5 0.2 3.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 CDJ83758.1 - 1.1e-10 40.5 6.6 0.0039 17.0 0.0 4.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 CDJ83758.1 - 3.9e-09 36.2 0.9 0.00022 21.0 0.1 4.4 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ83758.1 - 0.00015 21.1 3.1 0.065 12.7 0.0 3.6 4 0 0 4 4 4 2 EF hand PCI PF01399.27 CDJ83758.1 - 0.16 12.5 0.2 0.6 10.6 0.1 2.0 2 0 0 2 2 2 0 PCI domain HSP20 PF00011.21 CDJ83760.1 - 4.5e-21 74.9 0.1 5.1e-21 74.7 0.1 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ83760.1 - 0.00031 20.2 0.1 0.00042 19.8 0.1 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CABIT PF12736.7 CDJ83760.1 - 0.016 14.5 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Cell-cycle sustaining, positive selection, CS PF04969.16 CDJ83760.1 - 0.043 14.8 0.0 0.059 14.4 0.0 1.2 1 0 0 1 1 1 0 CS domain DUF5640 PF18692.1 CDJ83760.1 - 0.18 11.9 0.0 0.76 9.9 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5640) HSP20 PF00011.21 CDJ83761.1 - 4.8e-21 74.8 0.5 6e-21 74.5 0.5 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ83761.1 - 0.0059 16.1 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Kinesin PF00225.23 CDJ83762.1 - 5.6e-94 314.8 0.9 9.6e-94 314.0 0.9 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ83762.1 - 7e-16 58.5 0.7 2e-15 57.0 0.7 1.8 1 0 0 1 1 1 1 Microtubule binding Bac_DnaA PF00308.18 CDJ83762.1 - 0.032 14.1 0.4 0.087 12.6 0.1 1.8 2 0 0 2 2 2 0 Bacterial dnaA protein BTB PF00651.31 CDJ83764.1 - 7e-15 55.2 1.5 2.7e-08 34.0 0.0 3.3 3 0 0 3 3 3 2 BTB/POZ domain ABC_tran_CTD PF16326.5 CDJ83765.1 - 0.033 14.4 1.6 3.1 8.1 0.3 2.5 1 1 1 2 2 2 0 ABC transporter C-terminal domain Ribonuclease_3 PF00636.26 CDJ83766.1 - 3.5e-60 201.1 0.0 1.7e-35 121.8 0.0 3.0 2 1 0 2 2 2 2 Ribonuclease III domain PAZ PF02170.22 CDJ83766.1 - 4.1e-41 140.0 0.1 8.2e-41 139.0 0.1 1.5 1 0 0 1 1 1 1 PAZ domain Ribonucleas_3_3 PF14622.6 CDJ83766.1 - 3.9e-25 88.5 0.0 1.9e-15 57.1 0.0 4.0 3 1 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.14 CDJ83766.1 - 4.3e-24 84.5 0.0 1.2e-23 83.0 0.0 1.9 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 CDJ83766.1 - 2.4e-15 56.9 0.1 1.4e-14 54.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain dsrm PF00035.26 CDJ83766.1 - 0.0039 17.9 0.1 0.46 11.2 0.0 2.7 2 0 0 2 2 2 1 Double-stranded RNA binding motif Kinesin PF00225.23 CDJ83767.1 - 4.4e-94 315.1 0.5 7e-94 314.5 0.5 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ83767.1 - 3.4e-45 153.6 0.0 4e-44 150.1 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding DUF812 PF05667.11 CDJ83767.1 - 0.0027 16.7 11.2 0.0054 15.7 11.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF812) bZIP_1 PF00170.21 CDJ83767.1 - 0.007 16.4 4.0 0.007 16.4 4.0 3.1 3 1 0 3 3 2 1 bZIP transcription factor DivIC PF04977.15 CDJ83767.1 - 0.019 14.7 4.2 0.13 12.1 1.0 2.8 2 1 0 2 2 2 0 Septum formation initiator Macoilin PF09726.9 CDJ83767.1 - 0.064 11.8 10.9 0.13 10.8 10.9 1.4 1 0 0 1 1 1 0 Macoilin family HAP1_N PF04849.13 CDJ83767.1 - 0.081 12.1 17.4 0.95 8.6 0.5 3.1 3 1 0 4 4 4 0 HAP1 N-terminal conserved region Leu_zip PF15294.6 CDJ83767.1 - 0.1 12.1 13.5 0.24 10.9 13.5 1.5 1 0 0 1 1 1 0 Leucine zipper TMF_TATA_bd PF12325.8 CDJ83767.1 - 0.43 10.8 23.1 10 6.3 13.6 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding ATG16 PF08614.11 CDJ83767.1 - 0.61 10.3 21.5 2.3 8.4 13.8 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 CDJ83767.1 - 0.83 9.7 13.6 1.2 9.3 4.8 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 CDJ83767.1 - 0.94 8.3 16.3 4.6 6.0 8.2 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.8 CDJ83767.1 - 1.2 9.2 15.2 4.7 7.3 5.2 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 CDJ83767.1 - 2.1 9.0 18.8 0.51 11.0 2.6 3.9 3 1 1 4 4 4 0 Initiation control protein YabA DUF724 PF05266.14 CDJ83767.1 - 2.5 7.9 17.9 6.4 6.5 7.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Fez1 PF06818.15 CDJ83767.1 - 7.2 7.0 19.3 11 6.5 2.0 3.1 2 1 1 3 3 3 0 Fez1 DUF1664 PF07889.12 CDJ83767.1 - 8.3 6.5 12.9 22 5.1 5.4 3.2 3 1 1 4 4 3 0 Protein of unknown function (DUF1664) F-box-like PF12937.7 CDJ83768.1 - 2e-09 37.2 0.1 5.2e-09 35.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDJ83768.1 - 2.7e-08 33.5 0.3 2.7e-08 33.5 0.3 2.8 3 0 0 3 3 3 1 F-box domain Astacin PF01400.24 CDJ83769.1 - 1.9e-53 180.9 0.2 7.1e-53 179.1 0.1 1.9 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 CDJ83769.1 - 0.00045 19.9 0.1 0.00071 19.3 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CDJ83769.1 - 0.00085 19.2 0.6 0.0045 16.9 0.6 1.9 1 1 1 2 2 2 1 Matrixin CUB PF00431.20 CDJ83769.1 - 0.0013 19.1 0.2 0.0023 18.2 0.2 1.4 1 0 0 1 1 1 1 CUB domain ShK PF01549.24 CDJ83769.1 - 0.002 18.6 4.1 0.0089 16.5 4.1 2.2 1 0 0 1 1 1 1 ShK domain-like Reprolysin_3 PF13582.6 CDJ83769.1 - 0.0088 16.6 0.0 0.023 15.2 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 CDJ83769.1 - 0.012 14.5 0.1 0.02 13.8 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 DUF4953 PF16313.5 CDJ83769.1 - 0.018 14.3 0.1 0.032 13.5 0.1 1.3 1 0 0 1 1 1 0 Met-zincin Reprolysin_5 PF13688.6 CDJ83769.1 - 0.034 14.3 0.1 0.079 13.1 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 CDJ83769.1 - 0.046 13.6 0.2 0.53 10.2 0.1 2.2 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Sushi PF00084.20 CDJ83770.1 - 1.1e-07 32.3 1.7 1.5e-05 25.5 0.1 2.2 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) Synthase_beta PF11421.8 CDJ83770.1 - 0.1 13.3 0.1 0.32 11.8 0.0 1.8 2 0 0 2 2 2 0 ATP synthase F1 beta subunit Motile_Sperm PF00635.26 CDJ83771.1 - 6e-08 32.5 0.0 9.5e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain MgtC PF02308.16 CDJ83771.1 - 0.33 11.3 2.3 0.7 10.3 2.3 1.5 1 0 0 1 1 1 0 MgtC family Exo84_C PF16528.5 CDJ83772.1 - 2.9e-18 66.4 0.6 4.2e-17 62.7 0.0 2.5 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 CDJ83772.1 - 1.5e-14 53.8 3.5 1.5e-14 53.8 3.5 2.1 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 CDJ83772.1 - 0.00079 19.5 0.7 0.0027 17.8 0.7 1.9 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 PWWP PF00855.17 CDJ83773.1 - 9.6e-14 51.6 0.1 2.9e-13 50.0 0.1 1.9 1 0 0 1 1 1 1 PWWP domain AT_hook PF02178.19 CDJ83773.1 - 0.17 11.8 2.6 1.9 8.6 0.4 3.2 2 0 0 2 2 2 0 AT hook motif Pkinase PF00069.25 CDJ83775.1 - 6e-22 78.3 0.0 9e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ83775.1 - 8.6e-12 44.9 0.0 1.3e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ83775.1 - 6.6e-05 21.9 1.3 0.00014 20.8 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Fructosamin_kin PF03881.14 CDJ83775.1 - 0.0012 18.1 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 CDJ83775.1 - 0.015 15.2 0.0 0.5 10.2 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family FLYWCH PF04500.16 CDJ83776.1 - 0.0063 16.6 0.9 0.0063 16.6 0.9 2.2 2 0 0 2 2 2 1 FLYWCH zinc finger domain YdjO PF14169.6 CDJ83776.1 - 0.09 12.5 0.9 0.3 10.9 0.9 1.9 1 0 0 1 1 1 0 Cold-inducible protein YdjO ATP-synt_D PF01813.17 CDJ83777.1 - 5e-76 254.9 4.5 8.2e-76 254.2 4.5 1.3 1 0 0 1 1 1 1 ATP synthase subunit D TelA PF05816.11 CDJ83778.1 - 0.028 13.5 0.1 0.047 12.7 0.1 1.3 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) DUF3848 PF12959.7 CDJ83778.1 - 0.064 13.3 0.0 1.7 8.8 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3848) DUF2989 PF11207.8 CDJ83778.1 - 0.087 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) Pro_isomerase PF00160.21 CDJ83779.1 - 2.5e-36 125.3 0.1 2.9e-36 125.1 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase_Tyr PF07714.17 CDJ83780.1 - 7.9e-44 149.9 0.0 2.2e-21 76.3 0.0 3.9 2 2 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CDJ83780.1 - 1.5e-15 57.3 0.0 7e-06 25.6 0.0 3.8 2 2 1 3 3 3 2 Protein kinase domain Abhydrolase_3 PF07859.13 CDJ83780.1 - 0.0027 17.6 0.0 3.1 7.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF309 PF03745.14 CDJ83780.1 - 0.097 12.4 0.2 22 4.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF309) DUF1405 PF07187.11 CDJ83780.1 - 0.13 12.2 0.0 27 4.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1405) Cyclin_N PF00134.23 CDJ83781.1 - 1.4e-13 50.7 0.0 4.1e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CDJ83781.1 - 0.014 15.5 0.6 0.21 11.7 0.1 2.2 2 0 0 2 2 2 0 Cyclin, C-terminal domain WD40 PF00400.32 CDJ83782.1 - 9.2e-23 80.1 2.1 6.7e-06 26.8 0.1 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ83782.1 - 1.4e-10 41.4 0.0 0.15 12.4 0.0 4.9 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 CDJ83782.1 - 7.6e-07 28.7 0.2 2.7e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 LisH-like dimerisation domain CUB PF00431.20 CDJ83783.1 - 0.0022 18.3 0.0 0.0035 17.6 0.0 1.3 1 0 0 1 1 1 1 CUB domain ShK PF01549.24 CDJ83783.1 - 0.007 16.9 4.4 0.007 16.9 4.4 2.1 2 1 0 2 2 2 1 ShK domain-like Astacin PF01400.24 CDJ83783.1 - 0.013 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) ig PF00047.25 CDJ83784.1 - 8.1e-15 54.8 0.1 9.2e-07 29.0 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 CDJ83784.1 - 4.2e-14 52.4 0.2 1.2e-05 25.2 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ83784.1 - 3.4e-13 50.0 0.1 1.2e-06 29.0 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 CDJ83784.1 - 1e-12 48.2 0.3 3.9e-07 30.2 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 CDJ83784.1 - 2.8e-11 43.6 0.1 1.1e-05 25.7 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_4 PF16680.5 CDJ83784.1 - 0.0005 20.3 1.1 0.62 10.4 0.2 3.5 2 2 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 CDJ83784.1 - 0.00062 20.1 1.6 6.5 7.2 0.7 3.6 2 2 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 CDJ83784.1 - 0.0019 18.3 0.1 0.93 9.6 0.0 2.8 2 1 0 2 2 2 2 Izumo-like Immunoglobulin domain Ank_2 PF12796.7 CDJ83785.1 - 3.2e-58 194.3 1.0 6.8e-19 68.2 0.0 3.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ83785.1 - 9.8e-39 131.3 2.8 2.8e-12 46.9 0.2 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ83785.1 - 1.8e-31 104.6 0.4 7e-07 29.1 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 CDJ83785.1 - 1.6e-28 97.9 0.8 1.5e-08 34.7 0.3 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 CDJ83785.1 - 1.9e-27 95.0 3.0 2e-08 34.3 0.5 4.9 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Sec20 PF03908.13 CDJ83786.1 - 4.6e-20 71.3 0.8 4.6e-20 71.3 0.8 2.5 2 1 1 3 3 3 1 Sec20 Synaptobrevin PF00957.21 CDJ83786.1 - 0.015 15.1 0.1 0.015 15.1 0.1 3.0 2 1 1 3 3 3 0 Synaptobrevin Jas PF16135.5 CDJ83786.1 - 0.2 11.9 0.3 0.61 10.3 0.3 1.9 1 1 0 1 1 1 0 TPL-binding domain in jasmonate signalling Syntaxin_2 PF14523.6 CDJ83786.1 - 0.28 11.6 13.8 1.1 9.7 3.2 2.8 1 1 2 3 3 3 0 Syntaxin-like protein CRR7 PF12095.8 CDJ83786.1 - 0.31 11.5 2.7 1.4 9.4 0.0 2.6 2 1 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 AATF-Che1 PF13339.6 CDJ83786.1 - 0.46 11.1 7.5 0.97 10.1 7.5 1.7 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor FapA PF03961.13 CDJ83786.1 - 0.49 8.9 7.5 0.65 8.5 7.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Peptidase_S46 PF10459.9 CDJ83786.1 - 1 7.9 6.8 1.2 7.7 6.8 1.0 1 0 0 1 1 1 0 Peptidase S46 Uso1_p115_C PF04871.13 CDJ83786.1 - 1.4 9.3 11.0 2.3 8.6 6.1 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Endonuc_Holl PF10107.9 CDJ83786.1 - 4.1 7.2 7.9 0.98 9.3 4.1 1.9 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase BRE1 PF08647.11 CDJ83786.1 - 5.6 7.1 13.0 0.25 11.5 1.4 3.0 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase UPF0147 PF03685.13 CDJ83786.1 - 6.1 7.0 9.2 7 6.8 0.2 3.0 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0147) HisKA_3 PF07730.13 CDJ83786.1 - 9.3 6.9 11.3 2.3 8.8 0.9 3.1 2 1 1 3 3 3 0 Histidine kinase UQ_con PF00179.26 CDJ83787.1 - 1.4e-44 151.2 0.0 1.9e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ83787.1 - 9.3e-06 25.4 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CDJ83787.1 - 0.00034 20.9 0.0 0.00049 20.4 0.0 1.3 1 0 0 1 1 1 1 RWD domain UBA PF00627.31 CDJ83787.1 - 0.0057 16.5 0.7 0.0099 15.8 0.0 1.7 2 0 0 2 2 2 1 UBA/TS-N domain UFC1 PF08694.11 CDJ83787.1 - 0.04 13.6 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 UBA_4 PF14555.6 CDJ83787.1 - 0.16 11.8 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 UBA-like domain HLH PF00010.26 CDJ83788.1 - 2e-13 50.0 0.0 3.9e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain BLOC1_2 PF10046.9 CDJ83788.1 - 0.029 14.7 0.2 0.056 13.8 0.2 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.11 CDJ83788.1 - 0.034 14.4 2.5 0.043 14.0 2.5 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4094 PF13334.6 CDJ83788.1 - 0.064 13.7 0.7 0.18 12.2 0.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) AAA_12 PF13087.6 CDJ83790.1 - 2e-33 115.7 0.0 3.6e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ83790.1 - 1.9e-05 24.6 0.0 3.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ83790.1 - 6.7e-05 22.7 0.0 0.2 11.3 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CDJ83790.1 - 0.00012 22.4 0.0 0.0013 19.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 CDJ83790.1 - 0.033 14.1 0.0 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 Helicase PK_C PF02887.16 CDJ83790.1 - 0.091 13.0 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain Plexin_cytopl PF08337.12 CDJ83791.1 - 6.7e-135 450.9 0.4 7.6e-135 450.7 0.4 1.0 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain Pkinase_Tyr PF07714.17 CDJ83792.1 - 9.8e-62 208.6 0.0 1.5e-61 207.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ83792.1 - 1.2e-38 133.1 0.0 2e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDJ83792.1 - 0.0066 16.5 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 SH2 domain Collagen PF01391.18 CDJ83793.1 - 9.6e-13 47.7 117.0 2.1e-08 33.8 41.8 4.0 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) DUF148 PF02520.17 CDJ83794.1 - 2.3e-20 72.7 13.5 0.0017 18.4 0.7 7.7 7 1 1 8 8 8 4 Domain of unknown function DUF148 Lipase_chap PF03280.14 CDJ83794.1 - 4e-09 36.7 14.2 1 9.3 0.0 7.9 6 2 1 8 8 8 1 Proteobacterial lipase chaperone protein DUF3420 PF11900.8 CDJ83794.1 - 3e-06 27.3 16.3 0.93 9.7 0.1 7.7 8 0 0 8 8 8 2 Domain of unknown function (DUF3420) Tropomodulin PF03250.14 CDJ83794.1 - 6e-06 26.4 10.5 0.38 10.8 0.5 3.5 3 0 0 3 3 3 3 Tropomodulin DUF1542 PF07564.11 CDJ83794.1 - 3.6e-05 23.8 21.1 0.55 10.4 1.7 4.4 4 0 0 4 4 4 3 Domain of Unknown Function (DUF1542) DUF2249 PF10006.9 CDJ83794.1 - 0.0002 21.1 0.8 5.6 6.9 0.1 4.2 4 0 0 4 4 4 1 Uncharacterized conserved protein (DUF2249) SOCS_box PF07525.16 CDJ83794.1 - 0.00093 19.5 0.6 26 5.3 0.0 4.7 4 0 0 4 4 4 0 SOCS box CpxA_peri PF16527.5 CDJ83794.1 - 0.0022 18.4 0.6 1.9 8.9 0.1 4.4 4 0 0 4 4 4 1 Two-component sensor protein CpxA, periplasmic domain Baculo_8kDa PF06096.11 CDJ83794.1 - 0.0035 17.4 0.0 29 4.9 0.0 4.2 5 0 0 5 5 3 0 Baculoviridae 8.2 KDa protein Tai4 PF16695.5 CDJ83794.1 - 0.0076 16.8 6.9 1.8e+02 2.7 0.2 6.0 6 0 0 6 6 6 0 Type VI secretion system (T6SS), amidase immunity protein Myb_DNA-bind_3 PF12776.7 CDJ83794.1 - 0.0098 16.9 2.1 1.8e+02 3.2 0.2 5.3 6 1 0 6 6 5 0 Myb/SANT-like DNA-binding domain DUF3069 PF11269.8 CDJ83794.1 - 0.043 14.1 8.6 13 6.1 0.2 4.9 4 1 0 4 4 4 0 Protein of unknown function (DUF3069) DnaB PF00772.21 CDJ83794.1 - 0.064 13.3 0.1 61 3.8 0.0 4.0 3 0 0 3 3 3 0 DnaB-like helicase N terminal domain Adeno_terminal PF02459.15 CDJ83794.1 - 0.072 11.5 7.7 0.29 9.5 0.5 3.1 3 0 0 3 3 3 0 Adenoviral DNA terminal protein DUF3135 PF11333.8 CDJ83794.1 - 0.12 12.7 0.7 47 4.3 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3135) UBM PF14377.6 CDJ83794.1 - 0.15 11.5 3.6 23 4.6 0.1 4.2 4 0 0 4 4 4 0 Ubiquitin binding region Utp13 PF08625.11 CDJ83794.1 - 0.18 11.7 4.6 50 3.8 0.2 3.8 3 0 0 3 3 3 0 Utp13 specific WD40 associated domain GA PF01468.17 CDJ83794.1 - 0.19 12.0 14.4 5.6 7.3 0.6 4.1 4 0 0 4 4 4 0 GA module KIX_2 PF16987.5 CDJ83794.1 - 0.29 11.2 2.2 60 3.7 0.0 4.6 7 0 0 7 7 5 0 KIX domain Spb1_C PF07780.12 CDJ83794.1 - 0.32 10.6 15.2 3.9 7.0 0.5 4.1 4 0 0 4 4 4 0 Spb1 C-terminal domain RTX_C PF08339.10 CDJ83794.1 - 0.4 10.7 4.7 24 4.9 0.1 3.2 3 0 0 3 3 3 0 RTX C-terminal domain DUF1892 PF08987.10 CDJ83794.1 - 0.93 9.7 7.4 14 5.9 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1892) PP2C_C PF07830.13 CDJ83794.1 - 0.94 10.0 10.1 28 5.3 0.1 3.9 3 0 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain RelB PF04221.12 CDJ83794.1 - 1.1 9.3 3.4 46 4.1 0.0 3.6 4 0 0 4 4 3 0 RelB antitoxin DNA_repr_REX1B PF14966.6 CDJ83794.1 - 1.7 9.3 8.0 45 4.8 0.3 3.6 3 0 0 3 3 3 0 DNA repair REX1-B hnRNP_Q_AcD PF18360.1 CDJ83794.1 - 1.8 8.6 11.3 23 5.0 0.3 4.5 5 0 0 5 5 5 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain CAP_N PF01213.19 CDJ83794.1 - 9.4 5.6 9.4 0.32 10.4 0.5 2.9 4 0 0 4 4 4 0 Adenylate cyclase associated (CAP) N terminal RNase_Zc3h12a PF11977.8 CDJ83795.1 - 4e-16 59.2 0.0 5e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain RNase_Zc3h12a PF11977.8 CDJ83796.1 - 2.7e-06 27.2 0.0 4.4e-06 26.6 0.0 1.4 2 0 0 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain Astacin PF01400.24 CDJ83798.1 - 2.1e-36 125.4 0.2 2.6e-36 125.1 0.2 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M11 PF05548.11 CDJ83798.1 - 0.071 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Gametolysin peptidase M11 WD40 PF00400.32 CDJ83799.1 - 2.8e-37 126.0 17.2 6.5e-07 30.0 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ83799.1 - 1.4e-16 60.5 1.2 0.0086 16.3 0.0 5.5 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ83799.1 - 0.0001 21.4 0.8 0.13 11.2 0.1 4.4 1 1 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CDJ83799.1 - 0.00088 19.2 0.1 0.48 10.3 0.0 3.3 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 CDJ83799.1 - 0.0037 15.7 0.0 0.0094 14.3 0.0 1.6 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz WDCP PF15390.6 CDJ83799.1 - 0.0041 15.6 1.2 0.005 15.3 1.2 1.1 1 0 0 1 1 1 1 WD repeat and coiled-coil-containing protein family Sen15 PF09631.10 CDJ83799.1 - 0.052 13.8 0.1 22 5.4 0.0 3.2 2 1 0 3 3 3 0 Sen15 protein Phytochelatin_C PF09328.10 CDJ83799.1 - 0.075 12.4 0.2 1.3 8.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1984) Patched PF02460.18 CDJ83800.1 - 2.7e-22 78.7 0.0 3e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Patched family WD40 PF00400.32 CDJ83801.1 - 8.9e-38 127.6 16.5 4.3e-07 30.5 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ83801.1 - 7.2e-15 55.1 1.5 0.0093 16.3 0.0 5.7 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ83801.1 - 4.3e-05 22.6 0.5 0.068 12.1 0.1 4.1 2 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CDJ83801.1 - 0.00054 19.9 0.1 0.68 9.8 0.0 3.4 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 CDJ83801.1 - 0.0012 17.3 0.0 0.0023 16.3 0.0 1.4 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz WDCP PF15390.6 CDJ83801.1 - 0.025 13.0 0.9 0.029 12.7 0.9 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Sen15 PF09631.10 CDJ83801.1 - 0.042 14.2 0.1 15 6.0 0.0 3.2 2 1 0 3 3 3 0 Sen15 protein Phytochelatin_C PF09328.10 CDJ83801.1 - 0.065 12.5 0.1 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1984) KH_1 PF00013.29 CDJ83802.1 - 4.6e-09 36.0 1.6 5.9e-09 35.6 0.7 1.7 2 0 0 2 2 2 1 KH domain SLS PF14611.6 CDJ83802.1 - 0.028 14.3 1.2 0.052 13.4 0.9 1.6 1 1 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator CbiD PF01888.17 CDJ83802.1 - 0.089 12.1 0.5 0.16 11.3 0.5 1.4 1 0 0 1 1 1 0 CbiD DUF2171 PF09939.9 CDJ83802.1 - 0.095 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2171) 7tm_1 PF00001.21 CDJ83804.1 - 1.5e-13 50.7 8.0 1.5e-13 50.7 8.0 2.2 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) ATP_synt_H PF05493.13 CDJ83804.1 - 0.027 14.9 0.5 0.027 14.9 0.5 3.0 3 0 0 3 3 3 0 ATP synthase subunit H Alpha_kinase PF02816.18 CDJ83805.1 - 6.3e-59 199.2 0.1 1e-58 198.5 0.1 1.3 1 0 0 1 1 1 1 Alpha-kinase family Sel1 PF08238.12 CDJ83805.1 - 0.00014 22.4 8.0 0.28 11.9 0.4 4.3 4 0 0 4 4 4 2 Sel1 repeat DUF4428 PF14471.6 CDJ83805.1 - 0.0079 16.1 1.7 0.02 14.8 1.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4428) IBN_N PF03810.19 CDJ83806.1 - 4.4e-16 58.6 0.0 9.1e-16 57.5 0.0 1.6 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CDJ83806.1 - 0.0012 18.9 0.0 0.0047 17.0 0.0 2.0 2 0 0 2 2 2 1 Exportin 1-like protein SapB_2 PF03489.17 CDJ83807.1 - 0.0011 19.0 2.8 0.0024 17.9 0.3 2.6 3 0 0 3 3 3 1 Saposin-like type B, region 2 SapB_1 PF05184.15 CDJ83807.1 - 0.024 14.7 1.2 0.024 14.7 1.2 2.5 3 0 0 3 3 3 0 Saposin-like type B, region 1 BtpA PF03437.15 CDJ83808.1 - 8.4e-57 192.5 0.1 9.7e-57 192.3 0.1 1.0 1 0 0 1 1 1 1 BtpA family His_biosynth PF00977.21 CDJ83808.1 - 0.051 13.0 0.0 0.22 10.9 0.0 1.9 1 1 0 2 2 2 0 Histidine biosynthesis protein Ank_2 PF12796.7 CDJ83810.1 - 1.1e-17 64.4 6.7 8.5e-08 32.7 0.3 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ83810.1 - 1.3e-14 54.3 7.3 1.7e-07 31.6 0.3 4.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ83810.1 - 1e-12 47.0 3.0 4.3e-05 23.6 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 CDJ83810.1 - 3.1e-12 46.3 0.5 0.0076 16.7 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 CDJ83810.1 - 9.5e-12 44.9 2.4 1.1e-05 25.6 0.5 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) HTH_48 PF17906.1 CDJ83811.1 - 3.2e-17 62.4 1.3 6.5e-17 61.4 1.3 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_Tnp_Tc3_2 PF01498.18 CDJ83811.1 - 6.4e-07 29.5 1.7 1.2e-06 28.6 0.9 1.9 2 0 0 2 2 2 1 Transposase HTH_Tnp_IS630 PF01710.16 CDJ83811.1 - 2.2e-06 27.7 0.1 4.1e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 CDJ83811.1 - 1.8e-05 24.4 0.1 0.05 13.4 0.0 2.5 2 0 0 2 2 2 2 Homeodomain-like domain HTH_38 PF13936.6 CDJ83811.1 - 2e-05 24.3 0.3 0.00012 21.8 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.6 CDJ83811.1 - 2.5e-05 24.8 0.2 7.2e-05 23.3 0.0 1.9 2 0 0 2 2 1 1 Homeodomain-like domain HTH_28 PF13518.6 CDJ83811.1 - 0.00022 21.3 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_50 PF18024.1 CDJ83811.1 - 0.00041 19.9 0.0 0.0009 18.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 CDJ83811.1 - 0.011 16.0 0.3 4.4 7.7 0.0 2.4 1 1 1 2 2 2 0 Transposase HTH_11 PF08279.12 CDJ83811.1 - 0.014 15.3 0.1 0.029 14.3 0.1 1.5 1 0 0 1 1 1 0 HTH domain HTH_40 PF14493.6 CDJ83811.1 - 0.019 15.4 0.1 0.042 14.3 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 CDJ83811.1 - 0.023 14.7 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn helix HTH_10 PF04967.12 CDJ83811.1 - 0.024 14.4 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain HTH_6 PF01418.17 CDJ83811.1 - 0.055 13.5 0.0 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family TubC_N PF18563.1 CDJ83811.1 - 0.057 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 TubC N-terminal docking domain HTH_5 PF01022.20 CDJ83811.1 - 0.081 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_Tnp_ISL3 PF13542.6 CDJ83811.1 - 0.088 12.2 0.5 0.71 9.3 0.2 2.5 2 1 1 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 IF2_N PF04760.15 CDJ83811.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region NPDC1 PF06809.11 CDJ83812.1 - 4.9e-14 52.1 0.1 8.1e-14 51.4 0.1 1.3 1 0 0 1 1 1 1 Neural proliferation differentiation control-1 protein (NPDC1) Synapsin_N PF10581.9 CDJ83812.1 - 0.59 10.1 1.9 0.53 10.3 0.2 1.8 2 0 0 2 2 2 0 Synapsin N-terminal YebO PF13974.6 CDJ83812.1 - 4.3 7.5 9.7 15 5.7 0.1 2.5 1 1 1 2 2 2 0 YebO-like protein MIP PF00230.20 CDJ83813.1 - 3.4e-39 134.9 5.6 4.4e-39 134.5 5.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein Spermine_synth PF01564.17 CDJ83814.1 - 6.4e-05 22.4 0.1 0.00018 21.0 0.1 1.7 1 1 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_25 PF13649.6 CDJ83814.1 - 0.16 12.7 0.0 0.28 11.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Asp PF00026.23 CDJ83815.1 - 3.9e-41 141.5 0.0 1.1e-28 100.6 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ83815.1 - 1.7e-07 31.6 0.2 2.8e-07 30.9 0.2 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ83815.1 - 4.1e-05 23.4 0.0 0.00029 20.7 0.0 2.2 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal Peptidase_M28 PF04389.17 CDJ83816.1 - 7.3e-23 81.3 0.0 9.6e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.15 CDJ83816.1 - 5.5e-07 29.3 0.0 7.5e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Nicastrin Peptidase_M20 PF01546.28 CDJ83816.1 - 9.3e-06 25.5 0.0 1.4e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Collagen PF01391.18 CDJ83817.1 - 6e-44 147.6 189.4 7.2e-09 35.3 35.0 8.2 4 2 4 8 8 8 8 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ83817.1 - 1.8e-14 53.5 0.2 7.8e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 Nematode cuticle collagen N-terminal domain Fib_alpha PF08702.10 CDJ83817.1 - 0.0053 17.0 0.2 5 7.3 0.0 2.2 2 0 0 2 2 2 2 Fibrinogen alpha/beta chain family Nepo_coat_N PF03689.15 CDJ83817.1 - 0.046 13.7 0.0 20 5.2 0.0 2.7 2 0 0 2 2 2 0 Nepovirus coat protein, N-terminal domain AATF-Che1 PF13339.6 CDJ83817.1 - 0.13 13.0 0.0 30 5.3 0.0 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor SK_channel PF03530.14 CDJ83818.1 - 1.9e-34 118.0 0.6 1.9e-34 118.0 0.6 2.0 2 0 0 2 2 2 1 Calcium-activated SK potassium channel CaMBD PF02888.16 CDJ83818.1 - 2.7e-20 72.3 2.0 6.6e-20 71.1 2.0 1.7 1 0 0 1 1 1 1 Calmodulin binding domain Ion_trans_2 PF07885.16 CDJ83818.1 - 2.2e-11 43.6 5.6 2.2e-11 43.6 5.6 2.5 2 0 0 2 2 2 1 Ion channel Lig_chan PF00060.26 CDJ83818.1 - 8.4e-06 25.7 0.8 2.1e-05 24.4 0.8 1.8 1 0 0 1 1 1 1 Ligand-gated ion channel CoxIIa PF08113.11 CDJ83818.1 - 1.4 8.8 7.4 4.9 7.1 7.4 1.9 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family ABC_membrane PF00664.23 CDJ83820.1 - 4.6e-75 252.8 34.4 2.1e-38 132.5 14.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ83820.1 - 4.5e-52 176.2 0.3 6.5e-33 114.1 0.0 3.0 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 CDJ83820.1 - 9.6e-10 38.3 0.0 2.3e-06 27.2 0.0 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 CDJ83820.1 - 1e-08 34.7 0.0 0.00069 19.0 0.0 2.7 3 0 0 3 3 2 2 Zeta toxin AAA_16 PF13191.6 CDJ83820.1 - 1.5e-07 32.0 0.0 0.0064 16.9 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 CDJ83820.1 - 2.5e-07 30.3 0.8 0.012 15.3 0.2 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CDJ83820.1 - 3.3e-06 27.4 0.1 0.13 12.6 0.0 3.2 2 1 0 2 2 2 2 AAA domain DUF87 PF01935.17 CDJ83820.1 - 3.1e-05 24.2 0.2 0.051 13.7 0.1 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_24 PF13479.6 CDJ83820.1 - 4.8e-05 23.2 0.1 0.4 10.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 CDJ83820.1 - 5.3e-05 23.2 0.0 0.31 10.9 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 CDJ83820.1 - 6e-05 22.6 0.0 0.3 10.6 0.0 2.9 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_21 PF13304.6 CDJ83820.1 - 7.1e-05 22.8 0.3 0.022 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 CDJ83820.1 - 7.1e-05 23.0 0.0 0.37 10.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CDJ83820.1 - 0.00011 22.8 0.0 0.89 10.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 CDJ83820.1 - 0.00011 22.2 0.0 0.18 11.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 CDJ83820.1 - 0.00013 21.8 0.2 0.014 15.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain APS_kinase PF01583.20 CDJ83820.1 - 0.00045 20.1 0.2 0.13 12.2 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase ABC_ATPase PF09818.9 CDJ83820.1 - 0.00052 18.9 0.0 0.0012 17.7 0.0 1.5 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 CDJ83820.1 - 0.00059 19.5 0.0 0.27 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 CDJ83820.1 - 0.0014 18.4 0.1 0.63 9.7 0.0 2.9 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.20 CDJ83820.1 - 0.0014 17.9 0.1 2.1 7.4 0.0 2.8 3 0 0 3 3 2 2 G-protein alpha subunit IstB_IS21 PF01695.17 CDJ83820.1 - 0.0015 18.3 0.0 1.8 8.2 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 CDJ83820.1 - 0.0069 16.6 0.1 3.1 8.0 0.1 3.1 3 0 0 3 3 2 1 AAA domain SRP54 PF00448.22 CDJ83820.1 - 0.0095 15.6 0.0 4.1 7.0 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Mg_chelatase PF01078.21 CDJ83820.1 - 0.013 14.9 0.0 1.3 8.4 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CDJ83820.1 - 0.021 15.2 0.1 17 5.9 0.0 3.2 3 0 0 3 3 2 0 RNA helicase AAA_15 PF13175.6 CDJ83820.1 - 0.021 14.5 5.0 1.9 8.1 0.0 3.3 4 0 0 4 4 3 0 AAA ATPase domain CbiA PF01656.23 CDJ83820.1 - 0.028 14.5 0.1 6.4 6.9 0.1 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 CDJ83820.1 - 0.032 14.3 0.1 3.1 7.9 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Cytidylate_kin PF02224.18 CDJ83820.1 - 0.036 13.8 0.1 1.8 8.3 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase Roc PF08477.13 CDJ83820.1 - 0.039 14.2 0.6 11 6.3 0.0 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase DEAD PF00270.29 CDJ83820.1 - 0.048 13.4 0.0 2.4 7.9 0.0 2.8 3 0 0 3 3 2 0 DEAD/DEAH box helicase NACHT PF05729.12 CDJ83820.1 - 0.048 13.6 0.2 10 6.0 0.0 2.6 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 CDJ83820.1 - 0.049 12.8 1.2 8.3 5.5 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain TsaE PF02367.17 CDJ83820.1 - 0.049 13.6 0.1 25 4.9 0.0 3.1 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 CDJ83820.1 - 0.069 13.6 0.0 7.9 6.9 0.0 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CDJ83820.1 - 0.079 12.0 0.0 10 5.1 0.0 2.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Gtr1_RagA PF04670.12 CDJ83820.1 - 0.1 12.0 3.2 0.99 8.7 0.0 3.3 4 0 0 4 4 4 0 Gtr1/RagA G protein conserved region Ploopntkinase3 PF18751.1 CDJ83820.1 - 0.12 12.3 0.1 5.5 6.9 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 PduV-EutP PF10662.9 CDJ83820.1 - 0.12 12.1 0.3 14 5.4 0.1 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CtIP_N PF10482.9 CDJ83820.1 - 0.22 11.6 0.8 0.87 9.6 0.1 2.2 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain AAA_23 PF13476.6 CDJ83820.1 - 0.58 10.6 4.6 5.5 7.4 0.0 3.2 4 0 0 4 4 2 0 AAA domain Peptidase_M1 PF01433.20 CDJ83821.1 - 5.6e-67 225.5 0.7 5.6e-67 225.5 0.7 1.6 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 CDJ83821.1 - 6.4e-52 177.1 0.4 6.4e-52 177.1 0.4 1.5 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 CDJ83822.1 - 1.7e-75 253.3 0.4 1.7e-75 253.3 0.4 1.5 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 CDJ83822.1 - 1.4e-48 166.1 0.4 2.3e-48 165.4 0.4 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CDJ83822.1 - 9.5e-44 149.8 0.0 8.2e-43 146.8 0.0 2.1 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Aminopep PF10023.9 CDJ83822.1 - 0.008 15.6 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 1 Putative aminopeptidase DUF2773 PF10971.8 CDJ83822.1 - 0.086 13.0 0.0 0.37 11.0 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) Peptidase_M1_N PF17900.1 CDJ83823.1 - 9.8e-45 153.0 0.0 1.2e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 CDJ83823.1 - 1.6e-15 57.3 0.0 2.3e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain CDO_I PF05995.12 CDJ83825.1 - 4.7e-64 214.8 0.0 5.7e-64 214.5 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 CDJ83825.1 - 0.11 11.9 0.2 0.35 10.3 0.2 1.7 1 1 0 1 1 1 0 PCO_ADO Tubulin PF00091.25 CDJ83826.1 - 5.9e-70 235.5 0.0 1e-69 234.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDJ83826.1 - 2.9e-42 143.8 0.1 4.9e-42 143.1 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CDJ83826.1 - 1.8e-05 25.1 0.0 4.5e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CDJ83826.1 - 0.021 14.5 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 CDJ83826.1 - 0.025 13.8 0.0 0.051 12.8 0.0 1.5 1 0 0 1 1 1 0 Tubulin like tRNA-synt_2b PF00587.25 CDJ83831.1 - 4.6e-39 134.2 0.0 7e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CDJ83831.1 - 1.2e-22 79.8 0.3 2.5e-22 78.8 0.3 1.5 1 0 0 1 1 1 1 Anticodon binding domain Tir_receptor_N PF07490.11 CDJ83831.1 - 0.16 11.8 0.0 0.23 11.2 0.0 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Cytochrom_B561 PF03188.16 CDJ83832.1 - 4.3e-34 117.6 7.4 4.3e-34 117.6 7.4 1.8 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF3995 PF13160.6 CDJ83832.1 - 0.18 12.2 2.2 0.68 10.3 0.4 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3995) TGF_beta PF00019.20 CDJ83833.1 - 1.3e-29 103.2 0.3 2.2e-29 102.5 0.3 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 CDJ83833.1 - 2.6e-09 37.2 0.0 3.7e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 TGF-beta propeptide DAN PF03045.15 CDJ83833.1 - 0.061 13.4 0.2 0.1 12.6 0.2 1.3 1 0 0 1 1 1 0 DAN domain KCT2 PF17818.1 CDJ83834.1 - 3.4e-05 24.1 2.6 4.6e-05 23.6 0.0 2.6 3 1 0 3 3 3 1 Keratinocyte-associated gene product Ada3 PF10198.9 CDJ83834.1 - 0.00016 21.8 0.2 0.00016 21.8 0.2 2.1 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 DUF883 PF05957.13 CDJ83834.1 - 0.048 14.3 0.3 13 6.4 0.1 3.2 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) MAM PF00629.23 CDJ83835.1 - 0.0033 17.4 0.1 0.76 9.7 0.0 2.7 2 0 0 2 2 2 2 MAM domain, meprin/A5/mu DUF2002 PF09400.10 CDJ83837.1 - 0.023 14.7 0.1 0.052 13.6 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2002) DUF3454 PF11936.8 CDJ83838.1 - 0.89 10.0 5.8 15 6.1 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3454) Zona_pellucida PF00100.23 CDJ83839.1 - 1.9e-13 50.8 0.1 3.7e-13 49.9 0.0 1.4 2 0 0 2 2 2 1 Zona pellucida-like domain Herpes_UL42 PF02282.16 CDJ83839.1 - 0.04 13.8 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase processivity factor (UL42) CUT PF02376.15 CDJ83840.1 - 1.6e-67 223.6 0.2 5.8e-23 80.8 0.1 3.6 3 0 0 3 3 3 3 CUT domain CASP_C PF08172.12 CDJ83840.1 - 3.5e-40 137.9 8.3 3.5e-40 137.9 8.3 5.1 2 2 1 3 3 3 1 CASP C terminal Homeodomain PF00046.29 CDJ83840.1 - 2.4e-13 49.7 3.8 9.9e-13 47.7 3.8 2.2 1 0 0 1 1 1 1 Homeodomain HNF-1_N PF04814.13 CDJ83840.1 - 0.00012 22.8 8.0 0.0031 18.2 0.8 4.7 4 1 0 4 4 4 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus HTH_34 PF13601.6 CDJ83840.1 - 0.0022 18.1 0.0 1.1 9.5 0.0 4.0 3 0 0 3 3 3 1 Winged helix DNA-binding domain Homeobox_KN PF05920.11 CDJ83840.1 - 0.013 15.4 0.1 0.039 13.9 0.1 1.9 1 0 0 1 1 1 0 Homeobox KN domain HTH_ABP1_N PF18107.1 CDJ83840.1 - 0.046 13.4 3.4 0.083 12.6 0.3 3.2 3 0 0 3 3 3 0 Fission yeast centromere protein N-terminal domain Nodulin_late PF07127.11 CDJ83840.1 - 0.3 11.5 0.3 0.53 10.7 0.3 1.3 1 0 0 1 1 1 0 Late nodulin protein RILP PF11461.8 CDJ83840.1 - 3.6 7.9 7.9 0.88 9.8 0.8 3.0 2 0 0 2 2 2 0 Rab interacting lysosomal protein Cmc1 PF08583.10 CDJ83841.1 - 0.0047 16.9 5.7 0.0063 16.5 2.6 2.2 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 CDJ83841.1 - 0.0078 16.3 3.0 0.0078 16.3 3.0 1.8 2 0 0 2 2 2 1 CHCH domain CX9C PF16860.5 CDJ83841.1 - 2.6 8.1 8.9 5.3 7.1 6.0 2.7 2 1 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, WD40 PF00400.32 CDJ83842.1 - 9e-10 39.0 6.1 0.035 15.0 0.0 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ83842.1 - 0.00022 21.5 0.0 0.8 10.1 0.0 4.9 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain SAE2 PF08573.10 CDJ83843.1 - 1.4 10.0 10.0 3 9.0 10.0 1.5 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus RNase_PH PF01138.21 CDJ83844.1 - 3.3e-22 79.4 0.1 1e-21 77.8 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CDJ83844.1 - 2e-09 37.3 0.0 4.2e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Prefoldin PF02996.17 CDJ83845.1 - 8e-25 87.1 1.5 1e-24 86.8 1.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Nsp1_C PF05064.13 CDJ83845.1 - 0.0021 17.9 1.9 0.0055 16.5 0.1 2.2 2 1 0 2 2 2 1 Nsp1-like C-terminal region Prefoldin_2 PF01920.20 CDJ83845.1 - 0.0049 16.8 1.0 0.0049 16.8 1.0 2.0 2 0 0 2 2 2 1 Prefoldin subunit Zein-binding PF04576.15 CDJ83845.1 - 0.01 16.1 2.8 0.26 11.6 0.2 2.2 2 0 0 2 2 2 0 Zein-binding Col_cuticle_N PF01484.17 CDJ83845.1 - 0.13 12.4 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Pkinase PF00069.25 CDJ83847.1 - 4.9e-49 167.1 0.0 8.4e-49 166.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ83847.1 - 5.4e-17 61.9 0.0 1.3e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ83847.1 - 0.00041 19.8 0.0 0.00082 18.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CDJ83847.1 - 0.0022 17.6 0.1 0.0059 16.2 0.1 1.7 1 0 0 1 1 1 1 RIO1 family 7tm_1 PF00001.21 CDJ83849.1 - 1.6e-11 44.0 25.2 2.2e-11 43.6 25.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Aa_trans PF01490.18 CDJ83850.1 - 8.2e-53 179.6 16.0 1.4e-32 112.9 11.7 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Ceramidase PF05875.12 CDJ83850.1 - 0.092 12.2 8.8 0.13 11.6 0.4 2.2 2 0 0 2 2 2 0 Ceramidase PNTB_4TM PF12769.7 CDJ83850.1 - 0.93 10.0 4.8 15 6.1 0.3 2.5 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch DUF1754 PF08555.10 CDJ83851.1 - 0.0052 17.6 18.6 0.36 11.6 10.6 2.7 1 1 1 2 2 2 2 Eukaryotic family of unknown function (DUF1754) Kin17_mid PF10357.9 CDJ83852.1 - 1.3e-47 160.8 3.6 1.3e-47 160.8 3.6 2.9 3 1 0 3 3 3 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 CDJ83852.1 - 4.9e-19 68.2 2.8 4.9e-19 68.2 2.8 1.9 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain zf-met PF12874.7 CDJ83852.1 - 0.013 15.9 6.5 0.025 15.0 6.5 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDJ83852.1 - 0.019 15.2 6.0 0.045 14.0 6.0 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding TFIID_NTD2 PF04494.15 CDJ83852.1 - 0.033 14.4 0.1 0.075 13.3 0.1 1.6 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain GPI PF06560.11 CDJ83852.1 - 0.088 12.1 0.0 0.28 10.4 0.0 1.9 2 0 0 2 2 2 0 Glucose-6-phosphate isomerase (GPI) zf-C2H2_2 PF12756.7 CDJ83852.1 - 0.22 11.9 8.0 0.37 11.1 3.9 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) CarbpepA_inh PF02977.15 CDJ83852.1 - 0.58 10.0 3.5 3.7 7.4 3.1 2.3 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor Phage_GP20 PF06810.11 CDJ83852.1 - 10 5.9 15.3 0.099 12.4 3.6 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 BNIP2 PF12496.8 CDJ83854.1 - 0.02 15.3 14.4 10 6.6 0.1 5.7 1 1 6 7 7 7 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Fis1_TPR_N PF14852.6 CDJ83854.1 - 6.6 6.5 20.4 3e+02 1.2 0.0 8.9 11 0 0 11 11 11 0 Fis1 N-terminal tetratricopeptide repeat AT_hook PF02178.19 CDJ83855.1 - 0.16 12.0 36.8 0.2 11.7 5.0 4.7 4 0 0 4 4 4 0 AT hook motif PI3K_1B_p101 PF10486.9 CDJ83855.1 - 1.1 6.9 7.6 1.4 6.6 7.6 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit KH_1 PF00013.29 CDJ83856.1 - 9.5e-26 89.4 1.5 5.5e-13 48.5 0.1 2.4 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 CDJ83856.1 - 0.0019 18.0 0.0 0.63 9.9 0.0 2.5 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 CDJ83856.1 - 0.012 15.4 0.0 0.97 9.4 0.0 2.3 2 0 0 2 2 2 0 KH domain SCVP PF17619.2 CDJ83857.1 - 1.1e-52 176.8 20.4 3.8e-23 82.2 1.8 4.0 3 1 1 4 4 4 3 Secreted clade V proteins DUF866 PF05907.13 CDJ83857.1 - 0.0019 18.1 2.4 0.55 10.1 0.1 3.1 3 0 0 3 3 3 2 Eukaryotic protein of unknown function (DUF866) Glyco_hydro_2_N PF02837.18 CDJ83857.1 - 0.0021 18.0 1.0 3.2 7.6 0.0 3.1 3 1 0 4 4 4 2 Glycosyl hydrolases family 2, sugar binding domain Membr_traf_MHD PF10540.9 CDJ83857.1 - 0.045 13.9 0.2 5.1 7.3 0.2 2.5 1 1 0 1 1 1 0 Munc13 (mammalian uncoordinated) homology domain DUF1508 PF07411.12 CDJ83857.1 - 0.1 12.5 1.4 25 4.8 0.1 3.4 2 2 0 2 2 2 0 Domain of unknown function (DUF1508) SCVP PF17619.2 CDJ83858.1 - 1.2e-39 135.1 3.5 4e-24 85.3 0.6 2.2 1 1 1 2 2 2 2 Secreted clade V proteins DUF866 PF05907.13 CDJ83858.1 - 0.044 13.7 0.1 3.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF866) CX PF01705.19 CDJ83859.1 - 1.3e-18 67.3 4.5 2.4e-18 66.4 4.5 1.5 1 0 0 1 1 1 1 CX module WBP-1 PF11669.8 CDJ83859.1 - 2.7 8.7 9.7 9.1 7.0 9.6 1.8 2 0 0 2 2 2 0 WW domain-binding protein 1 RVT_1 PF00078.27 CDJ83860.1 - 7.1e-26 91.1 0.0 8.6e-26 90.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Acyltransf_C PF16076.5 CDJ83861.1 - 2.4e-10 40.3 0.2 3.8e-10 39.7 0.2 1.3 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 CDJ83861.1 - 0.0024 17.5 0.0 0.0049 16.5 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase EzrA PF06160.12 CDJ83862.1 - 0.0035 15.6 3.0 0.0035 15.6 3.0 2.8 2 1 1 3 3 3 2 Septation ring formation regulator, EzrA zf-C4H2 PF10146.9 CDJ83862.1 - 0.004 17.5 0.0 0.025 14.9 0.0 2.4 1 0 0 1 1 1 1 Zinc finger-containing protein DUF1664 PF07889.12 CDJ83862.1 - 0.0076 16.3 5.6 0.48 10.5 0.8 3.8 3 1 0 3 3 3 2 Protein of unknown function (DUF1664) Lipoprotein_7 PF01540.16 CDJ83862.1 - 0.047 13.0 0.9 0.85 8.8 0.3 2.5 2 0 0 2 2 2 0 Adhesin lipoprotein Laminin_II PF06009.12 CDJ83862.1 - 0.082 12.9 3.9 0.11 12.5 0.2 3.0 3 1 0 3 3 3 0 Laminin Domain II PI3K_P85_iSH2 PF16454.5 CDJ83862.1 - 0.34 10.5 6.7 0.47 10.0 2.9 3.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain XhlA PF10779.9 CDJ83862.1 - 0.88 9.8 5.4 0.36 11.1 1.2 2.6 3 0 0 3 3 3 0 Haemolysin XhlA KASH PF10541.9 CDJ83862.1 - 1.6 9.0 5.6 0.62 10.4 2.2 2.3 2 1 0 2 2 2 0 Nuclear envelope localisation domain TMPIT PF07851.13 CDJ83862.1 - 8.7 5.5 6.2 2.8 7.1 1.9 2.4 2 0 0 2 2 2 0 TMPIT-like protein Kunitz_BPTI PF00014.23 CDJ83863.1 - 3.9e-166 539.3 144.7 2.4e-17 62.9 7.1 12.0 10 0 0 10 10 10 10 Kunitz/Bovine pancreatic trypsin inhibitor domain ADAM_spacer1 PF05986.14 CDJ83863.1 - 6.3e-31 106.8 0.0 1e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.19 CDJ83863.1 - 4.6e-24 84.4 100.2 9.9e-06 25.7 5.2 10.5 9 0 0 9 9 9 7 Thrombospondin type 1 domain I-set PF07679.16 CDJ83863.1 - 1.7e-10 40.8 0.0 5.6e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain PLAC PF08686.11 CDJ83863.1 - 4.6e-08 33.7 8.6 5.7e-07 30.2 8.6 3.3 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Ig_3 PF13927.6 CDJ83863.1 - 7.1e-07 29.7 0.0 2.5e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CDJ83863.1 - 0.0012 19.0 0.0 0.0034 17.5 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 CDJ83863.1 - 0.011 15.9 0.2 0.11 12.7 0.0 2.7 2 1 1 3 3 3 0 Immunoglobulin V-set domain 7tm_1 PF00001.21 CDJ83865.1 - 0.00049 19.5 3.6 0.00071 19.0 3.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDJ83865.1 - 0.018 14.3 1.9 0.019 14.3 1.9 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 CDJ83865.1 - 0.053 13.1 6.5 0.07 12.7 6.5 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx DDE_Tnp_1_7 PF13843.6 CDJ83866.1 - 1.5e-84 284.3 0.0 1.9e-84 284.0 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 BESS PF02944.20 CDJ83867.1 - 0.057 13.3 0.3 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 BESS motif Ssl1 PF04056.14 CDJ83870.1 - 2.7e-77 258.9 0.3 4.3e-77 258.3 0.3 1.3 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 CDJ83870.1 - 4.5e-12 46.6 0.1 8e-12 45.8 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 CDJ83870.1 - 1.1e-07 32.3 0.1 1.6e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.12 CDJ83870.1 - 1.8e-07 31.3 13.0 1.8e-07 31.3 13.0 3.0 2 2 0 2 2 2 1 TFIIH C1-like domain DZR PF12773.7 CDJ83870.1 - 0.00055 19.9 15.7 0.0054 16.7 8.9 2.7 2 0 0 2 2 2 2 Double zinc ribbon VWA_3 PF13768.6 CDJ83870.1 - 0.0046 16.9 0.0 0.012 15.6 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain C1_2 PF03107.16 CDJ83870.1 - 0.0074 16.6 2.0 0.0074 16.6 2.0 2.9 2 1 0 2 2 2 1 C1 domain zf-C2HC5 PF06221.13 CDJ83870.1 - 0.78 9.8 26.1 1.1 9.2 11.2 2.7 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-C2H2_6 PF13912.6 CDJ83870.1 - 0.82 9.7 5.6 3.8 7.6 0.0 4.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-ACC PF17848.1 CDJ83870.1 - 3.4 7.8 12.4 0.87 9.7 1.1 4.1 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain GrpE PF01025.19 CDJ83871.1 - 1.7e-44 151.4 1.6 2.1e-44 151.1 1.6 1.2 1 0 0 1 1 1 1 GrpE Metallophos PF00149.28 CDJ83872.1 - 7.8e-34 118.0 0.1 1e-33 117.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 CDJ83872.1 - 0.029 14.0 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF5378 PF17349.2 CDJ83872.1 - 0.072 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) DUF2615 PF11027.8 CDJ83873.1 - 3.5e-32 110.7 0.0 4e-32 110.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) Helicase_C_2 PF13307.6 CDJ83874.1 - 4.2e-44 150.7 0.0 1.2e-43 149.2 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 CDJ83874.1 - 4.4e-41 140.4 0.2 9.2e-41 139.4 0.2 1.6 1 0 0 1 1 1 1 DEAD_2 UCH PF00443.29 CDJ83874.1 - 4.2e-12 46.1 0.4 3.4e-11 43.1 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DEAD PF00270.29 CDJ83874.1 - 2.8e-05 23.9 0.0 0.031 14.0 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 CDJ83874.1 - 0.00071 19.6 0.0 0.29 11.1 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit UCH_1 PF13423.6 CDJ83874.1 - 0.011 15.4 0.2 0.032 13.8 0.2 1.8 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF5050 PF16472.5 CDJ83874.1 - 0.017 14.3 0.1 0.031 13.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5050) HBB PF06777.11 CDJ83874.1 - 0.083 12.6 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Helical and beta-bridge domain Trm56 PF01994.16 CDJ83874.1 - 0.084 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 tRNA ribose 2'-O-methyltransferase, aTrm56 PhoH PF02562.16 CDJ83874.1 - 0.12 11.8 0.0 16 4.9 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein UCH PF00443.29 CDJ83875.1 - 7.5e-17 61.7 0.0 1.9e-16 60.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase OTU PF02338.19 CDJ83875.1 - 1.6e-09 38.3 0.0 3.3e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease UCH_1 PF13423.6 CDJ83875.1 - 0.081 12.5 0.0 0.34 10.4 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase TPR_2 PF07719.17 CDJ83876.1 - 0.0011 19.0 0.9 0.96 9.7 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ83876.1 - 0.0011 18.7 2.4 0.12 12.2 0.1 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ83876.1 - 0.012 16.2 0.2 36 5.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ83876.1 - 0.02 15.1 5.1 0.25 11.6 0.5 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CDJ83876.1 - 0.033 14.4 0.2 39 4.8 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ83876.1 - 0.033 15.0 0.2 41 5.4 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ83876.1 - 0.037 14.3 0.1 7.8 6.9 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3819 PF12842.7 CDJ83876.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) LRR_8 PF13855.6 CDJ83877.1 - 3.2e-28 97.3 48.5 1.4e-08 34.4 6.9 3.8 1 1 4 5 5 5 5 Leucine rich repeat Rad51 PF08423.11 CDJ83877.1 - 2.6e-19 69.5 0.0 3.9e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Rad51 LRR_4 PF12799.7 CDJ83877.1 - 2.2e-16 59.7 21.6 8.5e-06 26.0 5.4 4.7 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) ATPase PF06745.13 CDJ83877.1 - 5.4e-12 45.6 0.0 8.4e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 KaiC LRR_1 PF00560.33 CDJ83877.1 - 1.9e-07 30.7 19.4 2.7 8.9 0.0 8.6 9 0 0 9 9 8 1 Leucine Rich Repeat AAA_25 PF13481.6 CDJ83877.1 - 2.3e-06 27.3 0.0 4.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 CDJ83877.1 - 4.4e-06 26.3 0.0 6.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_24 PF13479.6 CDJ83877.1 - 2.3e-05 24.2 0.0 4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF4533 PF15047.6 CDJ83877.1 - 0.00053 19.6 1.8 0.087 12.4 0.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF4533) AAA_22 PF13401.6 CDJ83877.1 - 0.0008 19.7 0.1 0.0021 18.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CDJ83877.1 - 0.0025 18.3 0.0 0.0052 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain PAXNEB PF05625.11 CDJ83877.1 - 0.0037 16.4 0.1 0.007 15.5 0.1 1.4 1 0 0 1 1 1 1 PAXNEB protein AAA_30 PF13604.6 CDJ83877.1 - 0.0042 16.8 0.0 0.0066 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CDJ83877.1 - 0.0043 17.5 0.0 0.0088 16.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LRR_6 PF13516.6 CDJ83877.1 - 0.0048 16.9 20.0 6.7 7.0 0.2 6.5 6 0 0 6 6 6 1 Leucine Rich repeat CbiA PF01656.23 CDJ83877.1 - 0.0049 16.9 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DnaB_C PF03796.15 CDJ83877.1 - 0.0065 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain ATP-synt_ab PF00006.25 CDJ83877.1 - 0.057 13.1 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Thymidylate_kin PF02223.17 CDJ83877.1 - 0.062 13.0 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase ABC_tran PF00005.27 CDJ83877.1 - 0.078 13.5 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 CDJ83877.1 - 0.082 12.6 0.1 0.51 10.0 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_16 PF13191.6 CDJ83877.1 - 0.14 12.5 0.1 0.4 11.0 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 CDJ83877.1 - 0.18 11.7 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea SH2 PF00017.24 CDJ83878.1 - 5.2e-13 48.9 0.0 8.2e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 SH2 domain PID PF00640.23 CDJ83878.1 - 2.1e-09 37.5 0.0 3.2e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) TPR_2 PF07719.17 CDJ83879.1 - 0.00033 20.6 2.0 3.3 8.1 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ83879.1 - 0.00041 20.8 0.7 3.6 8.2 1.3 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat PPR PF01535.20 CDJ83879.1 - 0.00063 19.8 1.5 0.63 10.4 0.0 3.7 4 0 0 4 4 4 2 PPR repeat TPR_1 PF00515.28 CDJ83879.1 - 0.00072 19.3 2.1 0.92 9.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ83879.1 - 0.0024 18.1 0.7 0.68 10.3 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat HNHc_6 PF16784.5 CDJ83879.1 - 0.01 15.4 0.2 0.018 14.6 0.2 1.3 1 0 0 1 1 1 0 Putative HNHc nuclease TPR_16 PF13432.6 CDJ83879.1 - 0.081 13.6 0.3 0.43 11.3 0.1 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_2 PF13041.6 CDJ83879.1 - 0.11 12.7 0.7 17 5.7 0.0 3.0 4 0 0 4 4 4 0 PPR repeat family DAO PF01266.24 CDJ83880.1 - 1.9e-50 172.4 0.1 2.4e-50 172.1 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 CDJ83880.1 - 1.7e-08 34.0 0.1 6.4e-06 25.6 0.1 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.24 CDJ83880.1 - 4.3e-08 32.7 5.7 1e-06 28.1 5.7 2.2 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CDJ83880.1 - 1.2e-06 28.1 1.7 9.7e-06 25.2 1.7 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDJ83880.1 - 6.3e-05 23.1 1.2 0.00015 21.9 1.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAO_M PF16350.5 CDJ83880.1 - 7e-05 23.1 0.0 0.00017 21.8 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain Trp_halogenase PF04820.14 CDJ83880.1 - 0.00015 20.7 0.9 0.22 10.4 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 CDJ83880.1 - 0.00023 20.5 0.1 0.00033 20.0 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDJ83880.1 - 0.0019 18.7 0.3 0.14 12.7 0.3 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CDJ83880.1 - 0.0053 15.9 2.7 0.0053 15.9 2.7 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 CDJ83880.1 - 0.016 14.5 1.2 0.083 12.1 0.8 1.9 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 CDJ83880.1 - 0.021 14.1 0.3 0.43 9.8 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ83880.1 - 0.025 13.3 2.8 0.066 11.9 1.9 1.9 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 CDJ83880.1 - 0.047 12.7 2.1 0.047 12.7 0.2 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 CDJ83880.1 - 0.093 12.0 0.2 0.18 11.1 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GCV_T PF01571.21 CDJ83881.1 - 1.5e-67 227.7 0.0 1.9e-67 227.4 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 CDJ83881.1 - 4.7e-17 61.7 0.0 3.1e-16 59.1 0.0 2.2 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 CDJ83881.1 - 0.013 15.7 0.0 0.38 10.9 0.0 2.2 1 1 1 2 2 2 0 Sarcosine oxidase, gamma subunit family MtrG PF04210.13 CDJ83881.1 - 0.018 14.9 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G Cu2_monoox_C PF03712.15 CDJ83881.1 - 0.02 14.4 0.2 0.042 13.3 0.2 1.5 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain MADF_DNA_bdg PF10545.9 CDJ83882.1 - 5.1e-08 33.1 0.1 1.1e-07 32.0 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 CDJ83882.1 - 0.0001 22.6 0.1 0.00018 21.8 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Glyco_transf_11 PF01531.16 CDJ83883.1 - 5.1e-20 71.9 0.0 1.1e-18 67.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 11 Macin PF14865.6 CDJ83884.1 - 1.6e-10 41.4 12.7 2.5e-10 40.8 12.7 1.3 1 1 0 1 1 1 1 Macin OS-D PF03392.13 CDJ83884.1 - 0.071 13.2 3.7 0.097 12.8 3.7 1.3 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D RRM_7 PF16367.5 CDJ83885.1 - 1.2e-16 60.6 0.1 3e-13 49.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif RRM_1 PF00076.22 CDJ83885.1 - 3.4e-16 58.8 0.1 3.1e-07 30.1 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Laminin_G_1 PF00054.23 CDJ83885.1 - 0.08 13.2 0.0 1.7 8.9 0.0 2.2 2 0 0 2 2 2 0 Laminin G domain TTR-52 PF01060.23 CDJ83886.1 - 8.2e-28 96.9 0.1 1.3e-27 96.3 0.1 1.3 1 0 0 1 1 1 1 Transthyretin-like family DUF4369 PF14289.6 CDJ83886.1 - 0.068 13.7 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4369) PH_15 PF17339.2 CDJ83887.1 - 2.2e-28 98.2 0.0 3.7e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 PH domain I-set PF07679.16 CDJ83888.1 - 4.2e-23 81.2 0.0 1.3e-11 44.4 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ83888.1 - 1.1e-21 77.2 0.0 2.9e-09 37.4 0.0 3.7 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 CDJ83888.1 - 1.6e-13 50.8 0.0 1.9e-07 31.3 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 CDJ83888.1 - 8.4e-09 35.5 0.0 0.0011 19.1 0.0 3.3 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 CDJ83888.1 - 0.00068 19.8 0.2 1.4 9.1 0.0 3.7 4 0 0 4 4 4 1 Immunoglobulin V-set domain Izumo-Ig PF16706.5 CDJ83888.1 - 0.02 15.0 0.0 0.58 10.2 0.0 2.5 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 CDJ83888.1 - 0.083 12.5 0.1 4.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain DDE_3 PF13358.6 CDJ83889.1 - 2.7e-06 27.2 0.0 3.4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease tRNA_int_end_N2 PF12928.7 CDJ83891.1 - 1.1e-05 25.5 0.0 2.9e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term Sulfatase PF00884.23 CDJ83892.1 - 3.3e-37 128.5 1.8 5.4e-37 127.8 1.8 1.3 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 CDJ83892.1 - 0.054 13.7 0.1 0.37 11.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) Guanylate_cyc PF00211.20 CDJ83893.1 - 5.8e-65 218.4 0.0 1.2e-64 217.3 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 CDJ83893.1 - 9.7e-44 149.9 0.1 1.3e-43 149.5 0.1 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 CDJ83893.1 - 1.7e-24 86.5 0.0 3.7e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ83893.1 - 9.5e-20 71.0 0.0 1.6e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 CDJ83893.1 - 4.3e-06 26.3 1.0 7.2e-06 25.6 0.4 1.7 2 0 0 2 2 2 1 Heme NO binding associated Shisa PF13908.6 CDJ83893.1 - 0.0029 17.9 0.0 0.0055 17.0 0.0 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Guanylate_cyc PF00211.20 CDJ83894.1 - 1.9e-49 167.8 1.4 1.3e-43 148.7 0.1 2.2 1 1 1 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 CDJ83894.1 - 2.6e-12 46.6 0.0 4e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ83894.1 - 2.9e-11 43.3 0.0 4.5e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 CDJ83894.1 - 4.5e-06 26.3 0.3 6.7e-06 25.7 0.3 1.2 1 0 0 1 1 1 1 Heme NO binding associated ISPD_C PF18706.1 CDJ83894.1 - 0.086 12.5 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain AMP-binding PF00501.28 CDJ83894.1 - 0.13 10.9 0.1 0.2 10.2 0.1 1.2 1 0 0 1 1 1 0 AMP-binding enzyme DDE_Tnp_1_7 PF13843.6 CDJ83895.1 - 3.7e-79 266.6 0.4 4.6e-79 266.3 0.4 1.1 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1_3 PF13612.6 CDJ83895.1 - 0.064 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain Peptidase_C2 PF00648.21 CDJ83896.1 - 1.5e-40 139.1 0.0 1.9e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease Peptidase_C2 PF00648.21 CDJ83897.1 - 2.4e-35 122.0 0.0 2.8e-35 121.8 0.0 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease bZIP_2 PF07716.15 CDJ83898.1 - 1.1e-07 31.8 7.3 2.2e-07 30.9 7.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CDJ83898.1 - 2.7e-05 24.2 9.0 4.4e-05 23.5 9.0 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 CDJ83898.1 - 0.0013 19.3 4.2 0.0019 18.6 4.2 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor DivIC PF04977.15 CDJ83898.1 - 0.0099 15.6 1.6 0.015 15.0 1.6 1.3 1 0 0 1 1 1 1 Septum formation initiator TMCO5 PF14992.6 CDJ83898.1 - 0.015 14.9 0.3 0.017 14.7 0.3 1.1 1 0 0 1 1 1 0 TMCO5 family Mpp10 PF04006.12 CDJ83898.1 - 0.017 13.6 1.5 0.019 13.4 1.5 1.0 1 0 0 1 1 1 0 Mpp10 protein MIP-T3_C PF17749.1 CDJ83898.1 - 0.019 14.9 0.9 0.029 14.3 0.9 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Cnn_1N PF07989.11 CDJ83898.1 - 0.034 14.3 1.0 0.052 13.7 1.0 1.3 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 TMF_DNA_bd PF12329.8 CDJ83898.1 - 0.043 13.8 3.0 0.07 13.1 3.0 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding MbeD_MobD PF04899.12 CDJ83898.1 - 0.069 13.3 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 MbeD/MobD like CCT_2 PF09425.10 CDJ83898.1 - 0.23 11.4 2.3 0.6 10.0 2.3 1.7 1 0 0 1 1 1 0 Divergent CCT motif Acyltransferase PF01553.21 CDJ83899.1 - 9.9e-06 25.2 0.0 3.4e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Acyltransferase DAGAT PF03982.13 CDJ83899.1 - 0.00018 20.5 0.0 0.00028 19.9 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol acyltransferase GntR PF00392.21 CDJ83899.1 - 0.0079 15.8 0.0 1.3 8.7 0.3 2.5 2 0 0 2 2 2 2 Bacterial regulatory proteins, gntR family GFRP PF06399.13 CDJ83901.1 - 3.7e-25 87.6 0.1 8.8e-15 54.4 0.1 2.0 1 1 1 2 2 2 2 GTP cyclohydrolase I feedback regulatory protein (GFRP) HicA_toxin PF07927.12 CDJ83901.1 - 0.0084 16.1 0.0 1.6 8.8 0.0 2.3 2 0 0 2 2 2 2 HicA toxin of bacterial toxin-antitoxin, DUF3926 PF13080.6 CDJ83901.1 - 0.021 14.8 0.1 7.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3926) GAD-like PF08887.11 CDJ83901.1 - 0.069 12.9 0.1 1.2 8.9 0.0 2.0 1 1 1 2 2 2 0 GAD-like domain DUF4177 PF13783.6 CDJ83901.1 - 0.082 13.2 0.3 0.7 10.2 0.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4177) PCI PF01399.27 CDJ83902.1 - 1.2e-07 32.2 0.0 3.2e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 PCI domain DUF4061 PF13270.6 CDJ83903.1 - 2.2e-07 31.1 4.1 2.2e-07 31.1 4.1 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4061) GCIP PF13324.6 CDJ83903.1 - 0.81 9.2 7.5 0.023 14.3 1.0 1.6 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting tRNA-synt_2b PF00587.25 CDJ83904.1 - 1.1e-30 106.9 0.0 2.3e-30 105.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) BSD PF03909.17 CDJ83904.1 - 2.1e-22 78.9 0.6 2.5e-17 62.6 0.1 2.8 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 CDJ83904.1 - 1.2e-15 57.6 0.1 4.3e-15 55.8 0.0 2.0 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain PAPS_reduct PF01507.19 CDJ83904.1 - 0.11 12.6 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Vir_act_alpha_C PF10400.9 CDJ83904.1 - 0.25 12.0 1.5 1.2 9.9 1.5 2.2 1 0 0 1 1 1 0 Virulence activator alpha C-term DUF1758 PF05585.12 CDJ83905.1 - 0.0023 17.7 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase (DUF1758) DUF1759 PF03564.15 CDJ83906.1 - 2.4e-26 92.4 1.3 3.8e-26 91.8 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) RbsD_FucU PF05025.13 CDJ83906.1 - 0.12 12.8 0.1 0.29 11.6 0.1 1.6 1 0 0 1 1 1 0 RbsD / FucU transport protein family SpuA_C PF18033.1 CDJ83906.1 - 0.13 12.4 0.2 2 8.5 0.0 2.7 3 0 0 3 3 3 0 SpuA C-terminal Exo_endo_phos_2 PF14529.6 CDJ83908.1 - 0.00079 19.3 0.0 0.0014 18.5 0.0 1.4 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase DUF4440 PF14534.6 CDJ83910.1 - 4.9e-16 59.1 0.1 5.6e-16 58.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 CDJ83910.1 - 2e-10 41.2 0.5 2.7e-10 40.8 0.5 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 CDJ83910.1 - 5e-07 29.9 0.5 2.4e-06 27.7 0.5 1.8 1 1 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.20 CDJ83910.1 - 2e-05 25.1 0.0 8.2e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain CaMKII_AD PF08332.10 CDJ83910.1 - 0.00011 22.3 0.0 0.0003 20.9 0.0 1.6 1 1 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain SnoaL_3 PF13474.6 CDJ83910.1 - 0.0014 18.9 0.0 0.0019 18.4 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 CDJ83910.1 - 0.076 12.8 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase F-box PF00646.33 CDJ83912.1 - 0.12 12.2 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 F-box domain Conotoxin PF02950.17 CDJ83913.1 - 0.021 15.8 0.1 0.028 15.4 0.1 1.2 1 0 0 1 1 1 0 Conotoxin LEAP-2 PF07359.11 CDJ83913.1 - 0.022 14.6 0.1 0.026 14.4 0.1 1.2 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) ETRAMP PF09716.10 CDJ83913.1 - 0.045 13.8 0.2 0.05 13.7 0.2 1.1 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Ac81 PF05820.11 CDJ83913.1 - 0.059 12.9 0.0 0.071 12.7 0.0 1.1 1 0 0 1 1 1 0 Baculoviridae AC81 7TM_GPCR_Srx PF10328.9 CDJ83914.1 - 2.5e-08 33.9 13.6 3.4e-08 33.4 13.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 CDJ83914.1 - 9.7e-06 25.1 16.4 1.3e-05 24.7 16.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1679 PF07914.11 CDJ83915.1 - 1.2e-120 403.2 1.5 1.4e-120 403.0 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 CDJ83915.1 - 1.7e-21 76.8 0.5 2.8e-21 76.1 0.5 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 CDJ83915.1 - 1.7e-14 54.3 0.0 2.7e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDJ83915.1 - 3.2e-07 30.2 0.0 5.5e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 CDJ83915.1 - 0.015 14.5 0.0 0.051 12.8 0.0 1.7 2 0 0 2 2 2 0 Fructosamine kinase DUF1679 PF07914.11 CDJ83916.1 - 2.5e-231 767.8 2.2 1.4e-115 386.5 0.2 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) EcKinase PF02958.20 CDJ83916.1 - 4.4e-39 134.5 3.8 3e-19 69.4 0.1 2.4 2 0 0 2 2 2 2 Ecdysteroid kinase APH PF01636.23 CDJ83916.1 - 1e-18 68.1 0.5 7.6e-09 35.8 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDJ83916.1 - 1e-09 38.3 0.4 0.00076 19.1 0.0 2.5 2 0 0 2 2 2 2 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 CDJ83916.1 - 6.4e-09 35.4 4.5 0.00031 20.0 0.3 3.2 3 0 0 3 3 3 2 Fructosamine kinase Kdo PF06293.14 CDJ83916.1 - 1.6e-05 24.4 0.5 0.18 11.2 0.1 3.0 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1087 PF06465.13 CDJ83916.1 - 0.014 15.4 0.5 1.5 8.9 0.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) TetR_C_26 PF17934.1 CDJ83916.1 - 0.029 14.7 0.2 14 6.1 0.1 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Epiglycanin_C PF14654.6 CDJ83916.1 - 0.044 13.8 0.0 14 5.8 0.0 2.6 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region DUF1254 PF06863.12 CDJ83916.1 - 0.17 12.0 0.0 2.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1254) DUF1679 PF07914.11 CDJ83917.1 - 4.7e-49 167.4 0.0 5.4e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 CDJ83917.1 - 3.9e-16 59.2 0.0 5.3e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 CDJ83917.1 - 4.1e-11 43.3 0.3 4.9e-11 43.0 0.3 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDJ83917.1 - 4.8e-05 23.1 0.1 6.6e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 CDJ83917.1 - 0.0052 16.2 1.2 0.0085 15.5 1.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 CDJ83918.1 - 1.9e-35 122.6 2.3 2e-35 122.4 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) DUF2202 PF09968.9 CDJ83918.1 - 0.0018 18.1 0.7 0.13 12.1 0.3 2.1 1 1 1 2 2 2 2 Uncharacterized protein domain (DUF2202) PB1-F2 PF11986.8 CDJ83918.1 - 0.083 13.1 0.5 0.22 11.8 0.2 1.8 1 1 1 2 2 2 0 Influenza A Proapoptotic protein PNMA PF14893.6 CDJ83919.1 - 0.0039 16.7 0.4 0.0061 16.0 0.4 1.3 1 1 0 1 1 1 1 PNMA Retrotrans_gag PF03732.17 CDJ83919.1 - 0.0039 17.4 0.0 0.0082 16.4 0.0 1.6 1 1 0 1 1 1 1 Retrotransposon gag protein SCAN PF02023.17 CDJ83919.1 - 0.014 15.2 0.5 0.095 12.5 0.1 2.3 3 0 0 3 3 3 0 SCAN domain CobT PF06213.12 CDJ83919.1 - 0.015 14.7 0.1 0.019 14.3 0.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nterm_IS4 PF13006.7 CDJ83919.1 - 0.082 13.1 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Insertion element 4 transposase N-terminal AAA_11 PF13086.6 CDJ83921.1 - 2.2e-08 34.2 0.1 2.9e-06 27.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ83921.1 - 3.6e-07 30.1 0.0 0.00035 20.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 CDJ83921.1 - 0.00046 19.9 0.0 0.00081 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ83921.1 - 0.0023 18.3 0.0 0.015 15.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 CDJ83921.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase UvrD-helicase PF00580.21 CDJ83921.1 - 0.15 11.5 0.3 0.25 10.8 0.3 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain MBOAT PF03062.19 CDJ83922.1 - 2.7e-15 56.6 2.5 2.7e-15 56.6 2.5 2.0 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Peptidase_C97 PF05903.14 CDJ83923.1 - 7.4e-37 126.5 0.0 9.5e-37 126.1 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain TPR_1 PF00515.28 CDJ83924.1 - 9.5e-08 31.6 5.0 0.65 9.9 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ83924.1 - 0.0002 21.6 7.2 0.078 13.3 0.1 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ83924.1 - 0.00024 21.7 5.7 0.92 10.5 0.1 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ83924.1 - 0.00028 20.8 11.9 0.89 9.8 0.1 6.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ83924.1 - 0.015 15.5 5.4 20 5.7 0.2 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ83924.1 - 0.038 14.0 0.3 7.4 6.9 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ83924.1 - 0.54 10.2 3.4 6.9 6.7 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat SH3_9 PF14604.6 CDJ83925.1 - 5.8e-33 112.5 0.6 4.7e-12 45.6 0.0 5.5 5 0 0 5 5 5 4 Variant SH3 domain SH3_1 PF00018.28 CDJ83925.1 - 2.2e-27 94.4 1.6 7.3e-09 35.1 0.0 5.0 5 0 0 5 5 5 3 SH3 domain RhoGEF PF00621.20 CDJ83925.1 - 5.8e-21 75.5 0.4 1.3e-20 74.5 0.0 1.8 2 0 0 2 2 2 1 RhoGEF domain SH3_2 PF07653.17 CDJ83925.1 - 6.8e-18 64.1 0.6 1e-06 28.3 0.0 5.7 6 0 0 6 6 6 3 Variant SH3 domain DUF1759 PF03564.15 CDJ83925.1 - 0.002 18.1 0.4 0.0056 16.6 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) BAR PF03114.18 CDJ83925.1 - 0.017 14.8 7.5 0.2 11.3 2.1 2.9 3 0 0 3 3 3 0 BAR domain hSH3 PF14603.6 CDJ83925.1 - 0.018 15.5 0.0 31 5.1 0.0 3.9 3 0 0 3 3 3 0 Helically-extended SH3 domain Asp PF00026.23 CDJ83926.1 - 1.8e-89 300.3 2.8 2.2e-89 300.0 2.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ83926.1 - 3.3e-12 47.0 8.2 2e-11 44.5 5.8 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ83926.1 - 0.0001 22.1 0.3 0.00051 19.9 0.0 2.3 2 1 1 3 3 3 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CDJ83926.1 - 0.0019 18.8 0.1 2 9.1 0.0 3.1 3 0 0 3 3 3 2 Aspartyl protease Nuc_sug_transp PF04142.15 CDJ83927.1 - 2.3e-128 427.8 19.5 2.8e-128 427.5 19.5 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CDJ83927.1 - 9.5e-06 25.8 36.4 3.1e-05 24.1 9.5 2.7 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CDJ83927.1 - 0.0092 15.2 17.9 0.065 12.4 17.9 2.2 1 1 0 1 1 1 1 UAA transporter family COX14 PF14880.6 CDJ83927.1 - 0.06 13.2 0.0 0.41 10.5 0.0 2.4 2 0 0 2 2 2 0 Cytochrome oxidase c assembly FUSC-like PF12805.7 CDJ83927.1 - 1.1 8.3 7.4 1 8.4 3.9 2.4 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS Halogen_Hydrol PF10112.9 CDJ83927.1 - 3.6 7.6 13.7 7.2 6.6 1.0 3.5 2 1 1 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Peptidase_A17 PF05380.13 CDJ83930.1 - 5.2e-40 137.1 3.1 9.2e-40 136.3 3.1 1.4 1 0 0 1 1 1 1 Pao retrotransposon peptidase RVT_1 PF00078.27 CDJ83930.1 - 2.1e-08 34.0 0.0 4.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Kinesin_assoc PF16183.5 CDJ83930.1 - 0.052 13.7 0.2 0.17 12.1 0.0 1.9 2 0 0 2 2 2 0 Kinesin-associated SPT16 PF08644.11 CDJ83930.1 - 0.31 11.2 2.3 27 4.9 0.1 3.0 2 1 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) DUF1759 PF03564.15 CDJ83931.1 - 2.9e-18 66.2 0.0 1.3e-17 64.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 CDJ83931.1 - 4.4e-11 42.8 0.0 1.3e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 CDJ83931.1 - 0.017 15.8 0.1 0.043 14.5 0.1 1.6 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 CDJ83931.1 - 0.043 13.3 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CDJ83931.1 - 0.12 12.9 0.0 0.36 11.4 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease EzrA PF06160.12 CDJ83931.1 - 0.18 9.9 9.1 0.33 9.1 9.1 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF3784 PF12650.7 CDJ83932.1 - 0.074 13.3 0.2 0.074 13.3 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) Connexin PF00029.19 CDJ83932.1 - 0.081 12.7 0.3 8.6 6.0 0.1 2.4 2 0 0 2 2 2 0 Connexin HLH PF00010.26 CDJ83934.1 - 1.5e-16 60.1 0.8 1.5e-16 60.1 0.8 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain ORC6 PF05460.13 CDJ83934.1 - 0.042 13.1 2.0 0.044 13.0 2.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) HORMA PF02301.18 CDJ83935.1 - 1.2e-25 90.4 1.0 1.5e-25 90.0 1.0 1.2 1 0 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 CDJ83935.1 - 0.00051 19.9 0.1 0.00093 19.1 0.1 1.5 2 0 0 2 2 2 1 Bacterial HORMA domain 2 Imm35 PF15567.6 CDJ83935.1 - 0.14 12.4 0.1 0.28 11.4 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 35 DnaJ PF00226.31 CDJ83936.1 - 1.3e-15 57.3 0.3 1.3e-15 57.3 0.3 3.0 3 0 0 3 3 3 1 DnaJ domain Myb_DNA-binding PF00249.31 CDJ83936.1 - 3.2e-10 40.0 8.7 6e-07 29.6 0.1 3.9 4 0 0 4 4 4 2 Myb-like DNA-binding domain RAC_head PF16717.5 CDJ83936.1 - 1e-08 36.1 6.2 1e-08 36.1 6.2 4.0 3 1 0 3 3 3 1 Ribosome-associated complex head domain Myb_DNA-bind_6 PF13921.6 CDJ83936.1 - 1.5e-07 31.6 1.7 0.00056 20.1 0.3 3.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUP PF00674.18 CDJ83936.1 - 0.0061 16.7 0.8 2.5 8.3 0.1 2.6 2 0 0 2 2 2 2 DUP family Ank_4 PF13637.6 CDJ83937.1 - 2.7e-13 50.1 0.4 1.8e-07 31.6 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ83937.1 - 2.3e-12 47.3 0.3 3.2e-12 46.8 0.3 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ83937.1 - 6e-10 39.1 1.5 0.011 16.1 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 CDJ83937.1 - 4e-09 36.0 0.2 0.1 13.2 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 CDJ83937.1 - 2.4e-06 27.7 0.2 0.019 15.3 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 CDJ83939.1 - 9.3e-35 120.1 0.0 2.5e-31 108.9 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CDJ83939.1 - 8.9e-21 74.4 0.0 5.9e-20 71.7 0.0 2.0 2 1 1 3 3 3 1 Protein kinase domain Kdo PF06293.14 CDJ83939.1 - 0.037 13.4 0.1 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family 7TM_GPCR_Srsx PF10320.9 CDJ83940.1 - 6.8e-51 173.1 13.7 9.7e-51 172.6 13.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 CDJ83940.1 - 1.5e-05 24.5 15.5 1.5e-05 24.5 15.5 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Asp PF00026.23 CDJ83941.1 - 6.3e-81 272.2 0.1 7.7e-81 271.9 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ83941.1 - 2.2e-09 37.8 8.7 5.9e-08 33.2 6.9 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ83941.1 - 0.00076 19.3 0.0 0.0026 17.5 0.0 2.0 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp PF00026.23 CDJ83942.1 - 5.3e-84 282.3 0.4 6.4e-84 282.1 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ83942.1 - 3.4e-11 43.7 7.5 1.3e-09 38.5 7.5 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ83942.1 - 1e-05 25.4 0.0 2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CDJ83942.1 - 0.18 12.4 0.3 1.7 9.3 0.2 2.5 3 0 0 3 3 3 0 Aspartyl protease Tcp11 PF05794.13 CDJ83944.1 - 1.1e-75 255.5 3.1 1.2e-75 255.3 3.1 1.0 1 0 0 1 1 1 1 T-complex protein 11 FliT PF05400.13 CDJ83944.1 - 0.00023 21.9 0.9 0.0022 18.7 0.2 2.6 2 0 0 2 2 2 1 Flagellar protein FliT ATP-synt_E PF05680.12 CDJ83945.1 - 1e-21 77.1 0.0 1.2e-21 76.8 0.0 1.0 1 0 0 1 1 1 1 ATP synthase E chain AMP-binding PF00501.28 CDJ83946.1 - 7.4e-88 295.0 0.0 9.4e-88 294.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ83946.1 - 2.7e-16 60.3 0.1 6.9e-16 59.0 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Evr1_Alr PF04777.13 CDJ83947.1 - 1.7e-22 79.8 2.0 1.7e-22 79.8 2.0 2.3 2 0 0 2 2 2 1 Erv1 / Alr family FAD_SOX PF18371.1 CDJ83947.1 - 4.2e-19 68.8 0.0 1e-18 67.6 0.0 1.6 1 0 0 1 1 1 1 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Thioredoxin PF00085.20 CDJ83947.1 - 8.9e-19 67.4 0.2 2.8e-18 65.8 0.2 1.9 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 CDJ83947.1 - 0.071 12.8 0.3 0.34 10.6 0.1 2.1 2 0 0 2 2 2 0 Redoxin Thioredoxin_2 PF13098.6 CDJ83947.1 - 0.84 10.1 3.3 0.8 10.2 0.2 2.5 3 0 0 3 3 3 0 Thioredoxin-like domain Methyltransf_25 PF13649.6 CDJ83948.1 - 4.1e-11 43.4 0.0 6.8e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ83948.1 - 2.5e-10 40.8 0.0 4.3e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ83948.1 - 4e-05 23.5 0.0 8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CDJ83948.1 - 0.00083 19.2 0.0 0.0031 17.3 0.0 1.9 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 CDJ83948.1 - 0.0013 18.6 0.0 0.0031 17.3 0.0 1.6 1 1 0 2 2 2 1 Methyltransferase domain Fibrillarin PF01269.17 CDJ83948.1 - 0.0014 17.8 0.0 0.0024 17.0 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin Methyltransf_12 PF08242.12 CDJ83948.1 - 0.014 16.1 0.0 0.029 15.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 CDJ83948.1 - 0.056 12.7 0.0 0.069 12.4 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase AMP-binding PF00501.28 CDJ83949.1 - 0.0086 14.7 0.0 0.013 14.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme FYTT PF07078.11 CDJ83949.1 - 0.094 12.0 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Forty-two-three protein PIF1 PF05970.14 CDJ83950.1 - 7.7e-103 344.5 0.0 1.1e-102 343.9 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AMP-binding_C PF13193.6 CDJ83950.1 - 5.5e-16 59.3 0.5 1.4e-15 58.0 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AAA_30 PF13604.6 CDJ83950.1 - 4e-12 46.3 0.0 7.5e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ83950.1 - 3.6e-06 27.4 0.0 8e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CDJ83950.1 - 0.0061 15.7 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 CDJ83950.1 - 0.016 15.6 0.0 0.21 12.0 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain ResIII PF04851.15 CDJ83950.1 - 0.03 14.3 0.0 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Ly-6_related PF06579.12 CDJ83952.1 - 6.2e-36 123.4 0.2 7.2e-36 123.2 0.2 1.0 1 0 0 1 1 1 1 Caenorhabditis elegans ly-6-related protein QVR PF17064.5 CDJ83952.1 - 0.027 14.7 1.5 0.22 11.8 1.5 2.1 1 1 0 1 1 1 0 Sleepless protein Ribosomal_60s PF00428.19 CDJ83953.1 - 0.015 15.9 3.0 0.03 14.9 3.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Forkhead_N PF08430.12 CDJ83953.1 - 9.8 6.8 47.8 19 5.8 47.8 1.5 1 1 0 1 1 1 0 Forkhead N-terminal region CBM_21 PF03370.13 CDJ83955.1 - 1.1e-30 106.0 0.8 2.1e-30 105.2 0.8 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CDJ83955.1 - 4.6e-15 55.9 0.6 1.2e-14 54.6 0.6 1.7 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Exo_endo_phos_2 PF14529.6 CDJ83957.1 - 1.4e-06 28.2 0.4 1.2e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 CDJ83958.1 - 1.2e-13 51.1 0.0 1.5e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EntA_Immun PF08951.10 CDJ83958.1 - 0.09 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Enterocin A Immunity FCH PF00611.23 CDJ83959.1 - 9.8e-16 57.8 0.0 2.2e-14 53.5 0.1 2.8 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 CDJ83959.1 - 1.1e-12 47.3 0.0 2e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CDJ83959.1 - 2.8e-12 46.3 0.0 5.1e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CDJ83959.1 - 3.4e-08 33.0 0.0 8.9e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF4600 PF15372.6 CDJ83959.1 - 0.035 14.5 3.7 0.11 12.9 3.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) DUF2228 PF10228.9 CDJ83959.1 - 0.061 13.1 0.6 0.11 12.3 0.6 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) DUF4398 PF14346.6 CDJ83959.1 - 0.094 13.3 2.3 0.21 12.2 2.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) MamL-1 PF09596.10 CDJ83959.1 - 0.098 12.9 1.3 0.39 11.0 1.3 2.1 1 0 0 1 1 1 0 MamL-1 domain YscO PF07321.12 CDJ83959.1 - 0.18 11.8 7.7 0.12 12.3 5.2 1.9 2 0 0 2 2 2 0 Type III secretion protein YscO DUF4629 PF15442.6 CDJ83959.1 - 0.98 9.6 8.4 0.079 13.2 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4629) Brr6_like_C_C PF10104.9 CDJ83959.1 - 1.4 8.7 4.4 0.49 10.2 0.2 2.1 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain DUF829 PF05705.14 CDJ83961.1 - 4.4e-37 128.3 0.1 5.5e-37 127.9 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Peptidase_S9 PF00326.21 CDJ83961.1 - 0.0036 16.8 0.1 0.0055 16.2 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF829 PF05705.14 CDJ83962.1 - 9.7e-50 169.7 0.2 1.1e-49 169.5 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF3565 PF12088.8 CDJ83962.1 - 0.7 9.9 2.4 11 6.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3565) LIF_OSM PF01291.17 CDJ83963.1 - 0.13 12.4 1.0 0.21 11.7 0.1 1.8 2 0 0 2 2 2 0 LIF / OSM family MCM PF00493.23 CDJ83964.1 - 1.5e-98 328.3 0.0 1e-97 325.7 0.0 2.1 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 CDJ83964.1 - 5.5e-31 107.0 0.4 1.1e-30 106.1 0.4 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CDJ83964.1 - 1.5e-19 70.2 2.1 3.8e-19 68.9 2.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CDJ83964.1 - 1.8e-15 57.4 1.2 4.7e-15 56.0 0.5 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 CDJ83964.1 - 4.4e-09 36.0 0.1 3.4e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CDJ83964.1 - 2e-06 27.9 0.0 4.9e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CDJ83964.1 - 0.001 18.8 0.2 0.036 13.8 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 CDJ83964.1 - 0.0033 17.3 0.1 0.016 15.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ83964.1 - 0.1 12.9 0.2 0.56 10.6 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain Acyltransferase PF01553.21 CDJ83965.1 - 6e-11 42.1 0.0 2.4e-10 40.1 0.0 1.8 2 0 0 2 2 2 1 Acyltransferase Acyltransferase PF01553.21 CDJ83966.1 - 1.8e-22 79.4 0.0 3e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CDJ83966.1 - 2.3e-14 53.2 0.1 7.5e-14 51.6 0.1 2.0 1 0 0 1 1 1 1 Acyltransferase C-terminus PH PF00169.29 CDJ83967.1 - 2.3e-10 40.9 0.0 6.9e-10 39.4 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 CDJ83967.1 - 2.5e-08 34.3 0.0 5.4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain MCM PF00493.23 CDJ83968.1 - 1.5e-98 328.3 0.0 1e-97 325.7 0.0 2.1 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 CDJ83968.1 - 5.5e-31 107.0 0.4 1.1e-30 106.1 0.4 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CDJ83968.1 - 1.5e-19 70.2 2.1 3.8e-19 68.9 2.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CDJ83968.1 - 1.8e-15 57.4 1.2 4.7e-15 56.0 0.5 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 CDJ83968.1 - 4.4e-09 36.0 0.1 3.4e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CDJ83968.1 - 2e-06 27.9 0.0 4.9e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CDJ83968.1 - 0.001 18.8 0.2 0.036 13.8 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 CDJ83968.1 - 0.0033 17.3 0.1 0.016 15.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ83968.1 - 0.1 12.9 0.2 0.56 10.6 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain Acyltransferase PF01553.21 CDJ83969.1 - 6e-11 42.1 0.0 2.4e-10 40.1 0.0 1.8 2 0 0 2 2 2 1 Acyltransferase Acyltransf_C PF16076.5 CDJ83970.1 - 5.2e-15 55.3 0.3 1.1e-14 54.2 0.1 1.7 2 0 0 2 2 2 1 Acyltransferase C-terminus Acyltransferase PF01553.21 CDJ83971.1 - 3.5e-16 59.1 0.0 5.3e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Patatin PF01734.22 CDJ83972.1 - 1.7e-21 77.4 0.2 3.6e-21 76.3 0.2 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase DUF148 PF02520.17 CDJ83973.1 - 7.1e-11 42.2 0.1 0.00032 20.8 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function DUF148 Lipase_chap PF03280.14 CDJ83973.1 - 0.013 15.4 0.7 2 8.3 0.1 2.1 1 1 1 2 2 2 0 Proteobacterial lipase chaperone protein Rtt106_N PF18215.1 CDJ83973.1 - 0.12 12.2 0.2 10 6.0 0.0 3.2 4 0 0 4 4 4 0 Histone chaperone Rtt106 N-terminal domain Collagen PF01391.18 CDJ83974.1 - 3.7e-13 49.0 98.2 3.6e-09 36.2 38.1 5.1 3 2 0 3 3 3 2 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ83974.1 - 0.14 12.2 0.1 0.18 11.9 0.1 1.1 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Pkinase_Tyr PF07714.17 CDJ83975.1 - 5.1e-60 202.9 0.0 7.8e-60 202.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ83975.1 - 1.9e-37 129.1 0.1 3.3e-37 128.3 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDJ83975.1 - 0.0078 16.3 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 SH2 domain Plexin_cytopl PF08337.12 CDJ83976.1 - 6.5e-223 741.4 2.4 8e-223 741.1 2.4 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain 7tm_1 PF00001.21 CDJ83977.1 - 1e-50 172.6 10.3 1.3e-50 172.2 10.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ83977.1 - 4.4e-13 49.2 13.0 6.3e-13 48.7 13.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 CDJ83977.1 - 4.3e-10 39.6 10.1 4.3e-10 39.6 10.1 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 CDJ83977.1 - 9.4e-07 28.8 4.4 9.4e-07 28.8 4.4 2.3 3 0 0 3 3 3 1 Olfactory receptor Chromo PF00385.24 CDJ83978.1 - 3.6e-10 39.6 2.9 7.3e-10 38.6 2.9 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 CDJ83978.1 - 0.006 16.4 0.9 0.013 15.4 0.9 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain SH3_2 PF07653.17 CDJ83979.1 - 4.3e-07 29.5 0.0 6.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDJ83979.1 - 0.00015 21.3 0.0 0.00025 20.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CDJ83979.1 - 0.0097 15.7 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 CDJ83979.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 SH3 domain I-set PF07679.16 CDJ83980.1 - 1.6e-137 448.0 17.2 2.5e-23 82.0 0.0 10.7 11 0 0 11 11 11 9 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ83980.1 - 8e-79 260.3 1.0 1.1e-10 42.0 0.0 10.3 10 0 0 10 10 10 9 Immunoglobulin domain ig PF00047.25 CDJ83980.1 - 4.3e-34 116.5 2.2 7.5e-08 32.4 0.0 9.3 9 0 0 9 9 9 6 Immunoglobulin domain Ig_2 PF13895.6 CDJ83980.1 - 9.2e-28 96.4 0.0 6e-05 23.3 0.0 8.9 9 0 0 9 9 9 5 Immunoglobulin domain C2-set_2 PF08205.12 CDJ83980.1 - 5.2e-16 58.5 0.5 0.07 13.2 0.0 9.0 10 1 0 10 10 10 3 CD80-like C2-set immunoglobulin domain V-set PF07686.17 CDJ83980.1 - 7.2e-15 55.1 0.1 0.00076 19.6 0.0 7.4 7 1 0 7 7 7 2 Immunoglobulin V-set domain BiPBP_C PF06832.12 CDJ83980.1 - 7.2e-09 35.6 0.0 17 5.5 0.0 7.1 7 0 0 7 7 7 0 Penicillin-Binding Protein C-terminus Family Receptor_2B4 PF11465.8 CDJ83980.1 - 3.6e-06 27.1 0.0 0.1 12.8 0.0 3.6 4 0 0 4 4 3 2 Natural killer cell receptor 2B4 Ig_6 PF18452.1 CDJ83980.1 - 0.002 17.6 0.0 0.038 13.6 0.0 3.0 3 0 0 3 3 3 1 Immunoglobulin domain Izumo-Ig PF16706.5 CDJ83980.1 - 0.0033 17.5 0.1 12 6.0 0.0 4.3 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain PH_10 PF15411.6 CDJ83980.1 - 0.0046 17.2 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain C1-set PF07654.15 CDJ83980.1 - 0.0086 16.4 2.5 5.2 7.5 0.0 5.1 5 0 0 5 5 4 1 Immunoglobulin C1-set domain PH PF00169.29 CDJ83980.1 - 0.022 15.3 0.0 0.1 13.1 0.0 2.2 1 0 0 1 1 1 0 PH domain MelC1 PF06236.11 CDJ83980.1 - 0.04 14.0 0.1 0.14 12.2 0.1 2.0 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 PKD_3 PF16820.5 CDJ83980.1 - 0.055 13.2 3.3 6.6 6.6 0.0 5.1 6 0 0 6 6 6 0 PKD-like domain RhoGEF PF00621.20 CDJ83980.1 - 0.072 13.3 0.2 0.16 12.2 0.0 1.6 2 0 0 2 2 1 0 RhoGEF domain UPF0449 PF15136.6 CDJ83980.1 - 0.2 12.1 2.1 35 4.9 0.1 3.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 Big_6 PF17936.1 CDJ83980.1 - 0.24 11.7 3.2 4.7 7.5 0.0 4.5 6 0 0 6 6 6 0 Bacterial Ig domain Corona_NS4 PF03905.13 CDJ83980.1 - 0.33 11.0 4.8 1.3 9.1 4.8 2.0 1 0 0 1 1 1 0 Coronavirus non-structural protein NS4 Astacin PF01400.24 CDJ83981.1 - 2.3e-51 174.1 0.5 3.6e-51 173.5 0.5 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) DUF148 PF02520.17 CDJ83982.1 - 1e-23 83.5 6.3 1.3e-23 83.2 6.3 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 RmuC PF02646.16 CDJ83982.1 - 0.0036 16.5 2.2 0.005 16.0 2.2 1.1 1 0 0 1 1 1 1 RmuC family MAP65_ASE1 PF03999.12 CDJ83982.1 - 0.0057 15.4 3.0 0.0073 15.1 3.0 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DUF4422 PF14393.6 CDJ83982.1 - 0.013 15.3 2.2 0.017 15.0 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4422) YkyA PF10368.9 CDJ83982.1 - 0.022 14.4 5.2 0.04 13.6 5.2 1.4 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF241 PF03087.14 CDJ83982.1 - 0.055 13.3 0.9 0.074 12.9 0.9 1.1 1 0 0 1 1 1 0 Arabidopsis protein of unknown function ALMT PF11744.8 CDJ83982.1 - 0.09 11.6 1.4 0.11 11.3 1.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF948 PF06103.11 CDJ83982.1 - 0.11 12.7 0.4 0.19 12.0 0.4 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Taxilin PF09728.9 CDJ83982.1 - 0.18 10.9 9.7 0.26 10.4 9.7 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein ZYG-11_interact PF05884.12 CDJ83982.1 - 0.26 10.7 1.6 0.34 10.3 1.6 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF1043 PF06295.12 CDJ83982.1 - 1.7 8.6 6.5 7 6.7 6.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) DUF148 PF02520.17 CDJ83983.1 - 1.1e-23 83.4 4.6 1.3e-23 83.2 4.6 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 RmuC PF02646.16 CDJ83983.1 - 0.0021 17.2 1.5 0.0029 16.8 1.5 1.1 1 0 0 1 1 1 1 RmuC family MAP65_ASE1 PF03999.12 CDJ83983.1 - 0.0022 16.8 2.0 0.0027 16.5 2.0 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DUF4422 PF14393.6 CDJ83983.1 - 0.026 14.4 1.3 0.033 14.0 1.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4422) YkyA PF10368.9 CDJ83983.1 - 0.038 13.7 4.7 0.069 12.8 4.7 1.4 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein Taxilin PF09728.9 CDJ83983.1 - 0.059 12.5 6.6 0.08 12.1 6.6 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein CortBP2 PF09727.9 CDJ83983.1 - 0.063 13.2 3.7 0.083 12.8 3.7 1.1 1 0 0 1 1 1 0 Cortactin-binding protein-2 DUF948 PF06103.11 CDJ83983.1 - 0.11 12.7 0.3 0.17 12.2 0.3 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FliJ PF02050.16 CDJ83983.1 - 0.31 11.3 3.2 4.3 7.6 0.3 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein DUF1043 PF06295.12 CDJ83983.1 - 0.66 10.0 5.0 2.9 7.9 5.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) DUF148 PF02520.17 CDJ83984.1 - 2.5e-23 82.3 8.8 2.9e-23 82.1 8.8 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF148 MAP65_ASE1 PF03999.12 CDJ83984.1 - 0.0018 17.1 2.4 0.0023 16.7 2.4 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DUF4422 PF14393.6 CDJ83984.1 - 0.013 15.3 3.6 0.016 15.1 3.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4422) Erp_C PF06780.11 CDJ83984.1 - 0.042 13.9 0.2 0.055 13.5 0.2 1.2 1 0 0 1 1 1 0 Erp protein C-terminus Baculo_PEP_C PF04513.12 CDJ83984.1 - 0.051 13.6 0.4 0.068 13.2 0.4 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Dor1 PF04124.12 CDJ83984.1 - 0.054 12.2 1.8 0.067 11.9 1.8 1.0 1 0 0 1 1 1 0 Dor1-like family DUF948 PF06103.11 CDJ83984.1 - 0.067 13.5 0.7 0.11 12.8 0.7 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) ZYG-11_interact PF05884.12 CDJ83984.1 - 0.26 10.7 1.8 0.32 10.4 1.8 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 YkyA PF10368.9 CDJ83984.1 - 0.35 10.5 8.6 3.2 7.4 9.0 1.8 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein Fib_alpha PF08702.10 CDJ83984.1 - 0.73 10.0 3.5 1 9.6 3.5 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1043 PF06295.12 CDJ83984.1 - 5.4 7.0 9.3 27 4.8 9.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Homeodomain PF00046.29 CDJ83985.1 - 3.1e-20 71.8 5.6 5.2e-20 71.0 5.6 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ83985.1 - 0.058 13.3 0.3 0.058 13.3 0.3 2.2 2 0 0 2 2 2 0 Homeobox KN domain Troponin PF00992.20 CDJ83986.1 - 3.8e-44 150.2 13.7 3.8e-44 150.2 13.7 2.1 2 0 0 2 2 2 1 Troponin Glyco_hydro_31 PF01055.26 CDJ83986.1 - 0.23 10.6 0.5 0.32 10.1 0.5 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 RTC4 PF14474.6 CDJ83986.1 - 0.91 9.7 4.3 0.22 11.7 0.8 1.7 2 0 0 2 2 2 0 RTC4-like domain Recep_L_domain PF01030.24 CDJ83988.1 - 1.2e-18 67.3 18.1 0.0045 17.1 0.1 8.8 10 0 0 10 10 10 6 Receptor L domain GHL6 PF14871.6 CDJ83988.1 - 0.55 10.4 1.6 9 6.4 0.1 3.1 3 0 0 3 3 3 0 Hypothetical glycosyl hydrolase 6 Pyridoxal_deC PF00282.19 CDJ83989.1 - 3.4e-115 384.7 0.0 4.3e-77 259.4 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 CDJ83989.1 - 8.6e-05 21.9 0.0 0.00031 20.0 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II DUP PF00674.18 CDJ83989.1 - 0.0067 16.5 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 DUP family Beta_elim_lyase PF01212.21 CDJ83989.1 - 0.08 12.2 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Amidohydro_1 PF01979.20 CDJ83991.1 - 0.00049 19.5 0.0 0.00062 19.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Endostatin PF06482.11 CDJ83992.1 - 6.2e-60 203.3 0.0 7.8e-60 203.0 0.0 1.0 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin DUF1554 PF07588.11 CDJ83992.1 - 0.0011 18.7 0.5 0.011 15.5 0.5 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1554) IFT20 PF14931.6 CDJ83993.1 - 1.5e-34 118.7 6.1 1.9e-34 118.4 6.1 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 DUF641 PF04859.12 CDJ83993.1 - 0.0013 19.0 2.1 0.0013 19.0 2.1 1.5 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) CrtC PF07143.11 CDJ83993.1 - 0.033 14.9 0.5 0.045 14.4 0.5 1.1 1 0 0 1 1 1 0 CrtC N-terminal lipocalin domain HCMV_UL139 PF12507.8 CDJ83993.1 - 0.12 12.8 3.0 0.17 12.2 2.8 1.4 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein YabA PF06156.13 CDJ83993.1 - 0.15 12.7 2.0 0.4 11.3 0.4 2.0 1 1 1 2 2 2 0 Initiation control protein YabA DUF4061 PF13270.6 CDJ83993.1 - 0.24 11.7 7.9 3.2 8.1 4.7 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4061) OmpH PF03938.14 CDJ83993.1 - 0.59 10.5 10.9 0.88 9.9 10.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RNA_pol_Rpc4 PF05132.14 CDJ83994.1 - 2.4 8.6 5.6 0.76 10.2 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 IBR PF01485.21 CDJ83995.1 - 3.6e-05 23.9 7.2 3.6e-05 23.9 7.2 3.6 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain DNA_ligase_ZBD PF03119.16 CDJ83995.1 - 0.1 12.6 8.1 0.1 12.7 3.8 2.8 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DUF2370 PF10176.9 CDJ83995.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DDHD PF02862.17 CDJ83995.1 - 0.72 10.0 3.5 0.25 11.5 0.4 1.9 2 1 0 2 2 2 0 DDHD domain 7TM_GPCR_Srx PF10328.9 CDJ83996.1 - 7e-16 58.6 3.4 7.6e-16 58.5 3.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srt PF10321.9 CDJ83996.1 - 0.00074 18.6 4.2 0.00079 18.5 4.2 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt DUF2913 PF11140.8 CDJ83996.1 - 0.053 13.2 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) 7TM_GPCR_Srx PF10328.9 CDJ83997.1 - 1.3e-61 208.6 22.9 1.5e-61 208.4 22.9 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srt PF10321.9 CDJ83997.1 - 1.9e-12 46.8 16.3 2.4e-12 46.5 16.3 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt 7tm_1 PF00001.21 CDJ83997.1 - 1.5e-06 27.7 15.8 3.7e-06 26.4 13.8 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) Maf PF02545.14 CDJ83997.1 - 0.046 13.6 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 Maf-like protein DUF5448 PF17526.2 CDJ83998.1 - 0.086 13.0 0.1 0.13 12.5 0.1 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5448) Spermine_synth PF01564.17 CDJ84000.1 - 9.3e-08 31.7 0.0 1.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_4 PF02390.17 CDJ84000.1 - 0.00019 21.0 0.0 0.0049 16.4 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_3 PF01596.17 CDJ84000.1 - 0.00074 18.8 0.2 0.0015 17.7 0.2 1.5 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.6 CDJ84000.1 - 0.0028 17.4 0.0 0.004 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ84000.1 - 0.0051 16.7 0.0 0.012 15.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 CDJ84000.1 - 0.0063 16.3 0.0 0.009 15.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_17 PF12692.7 CDJ84000.1 - 0.012 15.7 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase Methyltransf_25 PF13649.6 CDJ84000.1 - 0.012 16.3 0.0 0.022 15.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CDJ84000.1 - 0.015 14.8 0.1 0.036 13.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.13 CDJ84000.1 - 0.015 14.7 0.2 0.024 14.1 0.2 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 CDJ84000.1 - 0.015 16.0 0.0 0.028 15.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_2_C PF02836.17 CDJ84002.1 - 1.4e-60 205.0 0.6 3.7e-60 203.6 0.6 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 CDJ84002.1 - 1.5e-21 77.0 0.5 3.8e-21 75.7 0.5 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 CDJ84002.1 - 5.8e-08 33.4 0.0 1.2e-07 32.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_cc PF11790.8 CDJ84002.1 - 0.03 13.9 0.1 0.051 13.1 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core LRR_4 PF12799.7 CDJ84003.1 - 4.9e-19 68.1 28.2 1.1e-07 32.0 1.4 5.4 1 1 5 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ84003.1 - 4.4e-14 52.0 12.9 1.3e-07 31.3 1.0 4.6 2 2 3 5 5 5 3 Leucine rich repeat LRR_9 PF14580.6 CDJ84003.1 - 5.8e-13 48.7 5.0 5.8e-08 32.4 0.1 3.2 2 1 1 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 CDJ84003.1 - 4.2e-06 26.4 9.2 0.87 9.8 0.2 5.7 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 CDJ84003.1 - 0.0015 18.8 13.8 2 9.3 0.7 6.9 6 1 0 6 6 6 1 Leucine Rich Repeat bZIP_1 PF00170.21 CDJ84003.1 - 0.059 13.5 2.4 0.73 10.0 2.4 2.5 1 1 0 1 1 1 0 bZIP transcription factor ATG16 PF08614.11 CDJ84003.1 - 4 7.6 11.6 0.025 14.8 2.4 2.0 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Pkinase PF00069.25 CDJ84004.1 - 3.6e-17 62.6 0.0 4.7e-17 62.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ84004.1 - 3.3e-15 56.1 0.0 3.8e-15 55.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_transf_7N PF13733.6 CDJ84005.1 - 0.00062 19.4 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 ThiW PF09512.10 CDJ84005.1 - 0.045 13.9 0.4 0.066 13.3 0.4 1.2 1 0 0 1 1 1 0 Thiamine-precursor transporter protein (ThiW) Herpes_UL16 PF03044.14 CDJ84005.1 - 0.13 11.5 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL16/UL94 family DUF3251 PF11622.8 CDJ84005.1 - 0.14 11.7 0.0 15 5.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3251) Pkinase_Tyr PF07714.17 CDJ84006.1 - 1.1e-93 313.2 0.0 1.5e-93 312.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ84006.1 - 7.4e-45 153.4 0.0 1.1e-44 152.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDJ84006.1 - 4.1e-19 68.5 0.0 9.2e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 CDJ84006.1 - 6.5e-16 57.7 0.1 2e-15 56.1 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CDJ84006.1 - 4.2e-14 52.1 0.1 1e-13 50.9 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CDJ84006.1 - 5.5e-09 35.6 0.0 1.4e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 CDJ84006.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 SH3 domain MADF_DNA_bdg PF10545.9 CDJ84007.1 - 2.1e-23 82.5 8.6 1.6e-11 44.3 0.9 2.9 3 1 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 CDJ84007.1 - 2.3e-06 27.9 6.4 0.00058 20.2 2.3 2.4 1 1 1 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 CDJ84007.1 - 0.0072 16.4 8.1 0.081 13.0 1.2 2.7 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Cu2_monoox_C PF03712.15 CDJ84008.1 - 5.7e-37 126.7 0.0 7.9e-37 126.2 0.0 1.2 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 CDJ84008.1 - 1.3e-24 86.9 0.2 2.8e-24 85.8 0.0 1.6 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain UBA PF00627.31 CDJ84009.1 - 0.00037 20.3 0.1 0.00062 19.6 0.1 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Ccdc124 PF06244.12 CDJ84010.1 - 1.8e-35 122.3 5.4 1.8e-35 122.3 5.4 2.3 1 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 CDJ84010.1 - 0.0015 18.9 0.3 0.0015 18.9 0.3 3.2 3 2 1 4 4 4 1 HMG (high mobility group) box MAP7 PF05672.11 CDJ84010.1 - 6 6.5 44.8 0.6 9.8 40.0 1.6 1 1 1 2 2 2 0 MAP7 (E-MAP-115) family Pex19 PF04614.12 CDJ84011.1 - 1.1e-40 140.0 6.9 1.6e-40 139.4 6.9 1.2 1 0 0 1 1 1 1 Pex19 protein family DUF1308 PF07000.11 CDJ84011.1 - 0.013 15.4 0.3 0.02 14.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) Phage_TAC_12 PF12363.8 CDJ84011.1 - 0.014 15.8 0.4 0.065 13.7 0.1 2.0 1 1 0 2 2 2 0 Phage tail assembly chaperone protein, TAC Ku_PK_bind PF08785.11 CDJ84011.1 - 0.014 15.5 0.2 0.027 14.6 0.2 1.5 1 0 0 1 1 1 0 Ku C terminal domain like DUF3450 PF11932.8 CDJ84011.1 - 0.054 12.8 5.5 0.085 12.2 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) EcKinase PF02958.20 CDJ84011.1 - 0.058 12.7 0.9 0.097 12.0 0.9 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase FliE PF02049.18 CDJ84011.1 - 0.17 12.0 9.6 0.56 10.4 8.6 2.1 1 1 1 2 2 2 0 Flagellar hook-basal body complex protein FliE Lant_dehydr_C PF14028.6 CDJ84011.1 - 0.19 11.2 1.7 16 4.9 1.7 2.1 1 1 0 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term DUF2937 PF11157.8 CDJ84011.1 - 0.48 10.1 5.8 0.81 9.4 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) DUF4200 PF13863.6 CDJ84011.1 - 0.54 10.7 7.2 0.14 12.5 3.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) TnpV PF14198.6 CDJ84011.1 - 2 8.5 7.1 4.9 7.2 0.5 2.7 2 1 1 3 3 3 0 Transposon-encoded protein TnpV GET2 PF08690.10 CDJ84011.1 - 6.2 6.4 9.7 7.3 6.2 9.1 1.7 1 1 0 1 1 1 0 GET complex subunit GET2 GCV_H PF01597.19 CDJ84012.1 - 4.9e-05 23.2 0.1 6.5e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Glycine cleavage H-protein MFS_1 PF07690.16 CDJ84013.1 - 2.8e-16 59.4 40.8 2.8e-16 59.4 40.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Kinesin PF00225.23 CDJ84014.1 - 3.9e-95 318.6 0.0 5e-95 318.2 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ84014.1 - 1.1e-38 132.5 0.0 2.2e-38 131.6 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Fez1 PF06818.15 CDJ84014.1 - 0.01 16.3 2.6 0.01 16.3 2.6 2.0 2 0 0 2 2 2 0 Fez1 NRBF2 PF08961.10 CDJ84014.1 - 0.011 15.3 1.4 0.011 15.3 1.4 1.9 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator P4Ha_N PF08336.11 CDJ84014.1 - 0.1 12.6 1.3 0.99 9.4 0.2 2.7 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region UCH PF00443.29 CDJ84016.1 - 0.18 11.3 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase PCI PF01399.27 CDJ84017.1 - 2e-14 54.0 0.2 5e-14 52.7 0.2 1.7 1 0 0 1 1 1 1 PCI domain TPR_19 PF14559.6 CDJ84017.1 - 8.4e-05 23.0 1.5 0.0016 18.9 0.3 3.2 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ84017.1 - 9e-05 22.7 3.7 0.082 13.2 0.7 3.0 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ84017.1 - 9.3e-05 22.2 2.3 0.53 10.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat RPN7 PF10602.9 CDJ84017.1 - 9.7e-05 22.1 0.1 0.00021 21.0 0.1 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_8 PF13181.6 CDJ84017.1 - 0.00012 22.0 0.3 0.015 15.4 0.1 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ84017.1 - 0.00017 21.4 0.5 0.25 11.5 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ84017.1 - 0.00036 21.1 3.5 0.058 14.2 0.2 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ84017.1 - 0.0038 17.0 0.2 1.3 9.0 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 CDJ84017.1 - 0.006 17.1 2.0 5.7 7.9 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ84017.1 - 0.017 15.8 6.3 0.064 13.9 2.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 CDJ84017.1 - 0.018 14.4 0.2 0.026 13.9 0.2 1.4 1 0 0 1 1 1 0 MalT-like TPR region CSN4_RPN5_eIF3a PF18420.1 CDJ84017.1 - 0.041 14.1 0.2 0.092 12.9 0.2 1.6 1 0 0 1 1 1 0 CSN4/RPN5/eIF3a helix turn helix domain SNAP PF14938.6 CDJ84017.1 - 0.063 12.7 0.5 0.26 10.7 0.6 1.9 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 CDJ84017.1 - 0.13 13.0 0.2 9 7.2 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Cpn60_TCP1 PF00118.24 CDJ84018.1 - 4.4e-153 510.4 11.4 5.1e-153 510.3 11.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EF-hand_7 PF13499.6 CDJ84019.1 - 2.4e-14 53.5 11.8 3.5e-12 46.6 5.9 2.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CDJ84019.1 - 2.9e-09 35.8 12.5 8e-05 21.9 0.1 3.9 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CDJ84019.1 - 4.5e-07 29.3 11.0 0.0015 18.3 1.3 3.9 4 0 0 4 4 4 3 EF-hand domain SPARC_Ca_bdg PF10591.9 CDJ84019.1 - 0.002 18.5 0.4 0.0049 17.2 0.4 1.7 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 CDJ84019.1 - 0.027 14.3 11.5 0.2 11.5 3.6 3.3 2 1 0 2 2 2 0 EF-hand domain pair PMBR PF09373.10 CDJ84019.1 - 0.14 12.4 0.7 7.7 6.9 0.0 3.7 5 0 0 5 5 5 0 Pseudomurein-binding repeat Band_7 PF01145.25 CDJ84020.1 - 3.2e-30 105.4 0.5 3.2e-30 105.4 0.5 1.8 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 CDJ84020.1 - 4.9e-26 90.6 1.5 1.1e-25 89.4 0.5 2.2 2 0 0 2 2 2 1 C-terminal region of band_7 Band_7_1 PF13421.6 CDJ84020.1 - 0.00041 20.1 0.1 0.00072 19.3 0.1 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family CHCH PF06747.13 CDJ84021.1 - 7.4e-10 38.7 4.4 7.4e-10 38.7 4.4 1.8 2 0 0 2 2 2 1 CHCH domain Fcf1 PF04900.12 CDJ84022.1 - 6.6e-37 125.9 0.7 1.1e-36 125.2 0.7 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 CDJ84022.1 - 1.5e-09 38.2 0.2 3.2e-09 37.1 0.0 1.6 2 0 0 2 2 2 1 PIN like domain Dynein_light PF01221.18 CDJ84022.1 - 0.045 14.1 0.0 0.096 13.0 0.0 1.5 1 0 0 1 1 1 0 Dynein light chain type 1 PH_17 PF18012.1 CDJ84023.1 - 1.1e-25 89.1 0.0 1.1e-23 82.7 0.0 2.4 2 0 0 2 2 2 1 PH domain PDZ PF00595.24 CDJ84023.1 - 2.5e-19 69.4 0.2 4.3e-19 68.6 0.2 1.4 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 CDJ84023.1 - 6.4e-13 49.1 0.0 2e-10 41.1 0.0 2.7 3 0 0 3 3 3 1 PH domain PDZ_6 PF17820.1 CDJ84023.1 - 3.6e-07 29.9 0.1 1e-06 28.5 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ84023.1 - 0.0002 21.6 0.3 0.00046 20.5 0.3 1.6 1 0 0 1 1 1 1 PDZ domain Laminin_G_2 PF02210.24 CDJ84023.1 - 0.022 15.3 0.0 0.067 13.8 0.0 1.8 1 0 0 1 1 1 0 Laminin G domain Pkinase PF00069.25 CDJ84024.1 - 2.6e-12 46.7 0.0 2.7e-12 46.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ84024.1 - 2.2e-06 27.1 0.0 2.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ84024.1 - 5.5e-05 22.1 0.0 8.3e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDJ84024.1 - 0.0055 16.7 0.0 0.012 15.6 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family zf-C2H2 PF00096.26 CDJ84025.1 - 1e-21 76.1 30.9 1.9e-05 24.9 0.7 5.6 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ84025.1 - 5e-18 64.6 35.0 4.7e-08 33.1 0.4 4.9 5 0 0 5 5 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDJ84025.1 - 2.3e-13 49.7 25.7 0.00079 20.1 0.6 5.9 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ84025.1 - 2e-05 24.8 15.1 0.014 15.7 0.2 4.8 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 CDJ84025.1 - 0.0018 18.0 21.1 0.028 14.2 0.3 5.3 5 0 0 5 5 5 3 C2H2-type zinc-finger domain zf_ZIC PF18366.1 CDJ84025.1 - 0.0068 16.5 0.2 0.0068 16.5 0.2 4.7 4 1 1 5 5 5 1 Zic proteins zinc finger domain zf-C2H2_8 PF15909.5 CDJ84025.1 - 0.03 14.6 12.4 0.34 11.2 2.9 2.8 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-met PF12874.7 CDJ84025.1 - 0.031 14.7 13.5 8.7 6.9 0.3 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 CDJ84025.1 - 0.14 12.6 0.4 0.14 12.6 0.4 2.3 2 1 1 3 3 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_aberr PF17017.5 CDJ84025.1 - 0.2 11.8 11.8 1.9 8.6 1.4 3.2 2 1 1 3 3 3 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 CDJ84025.1 - 2.3 8.0 7.4 21 5.0 0.1 3.7 4 0 0 4 4 4 0 zinc-finger C2H2-type CHORD PF04968.12 CDJ84025.1 - 6.8 7.5 21.1 3.6 8.4 0.9 4.9 3 1 2 5 5 5 0 CHORD Spermine_synth PF01564.17 CDJ84027.1 - 3.4e-05 23.3 0.1 7.4e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 CDJ84027.1 - 0.0058 16.5 0.0 0.0094 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain HAD_SAK_2 PF18143.1 CDJ84027.1 - 0.013 15.9 0.1 0.023 15.0 0.1 1.5 1 0 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins Methyltransf_25 PF13649.6 CDJ84027.1 - 0.043 14.5 0.0 0.088 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 CDJ84027.1 - 0.13 12.0 0.0 0.34 10.6 0.0 1.6 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AAA_19 PF13245.6 CDJ84028.1 - 0.021 15.2 0.0 0.036 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CDJ84028.1 - 0.025 14.3 1.8 0.051 13.3 1.4 1.6 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 CDJ84028.1 - 0.035 14.0 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Helicase AAA_11 PF13086.6 CDJ84028.1 - 0.069 12.9 0.0 0.091 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 CDJ84028.1 - 0.097 12.4 0.2 0.16 11.7 0.2 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase UvrD-helicase PF00580.21 CDJ84028.1 - 0.13 11.8 0.1 0.17 11.3 0.1 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain RRM_1 PF00076.22 CDJ84029.1 - 1.3e-07 31.3 0.0 9.8e-05 22.1 0.0 2.5 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Xan_ur_permease PF00860.20 CDJ84030.1 - 8.8e-84 281.4 21.0 1.4e-83 280.8 21.0 1.2 1 0 0 1 1 1 1 Permease family EF-hand_1 PF00036.32 CDJ84031.1 - 1.8e-28 95.9 15.6 2.5e-09 36.0 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CDJ84031.1 - 2.8e-25 87.9 11.1 1.9e-12 46.8 1.8 3.6 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 CDJ84031.1 - 1.1e-24 86.6 7.8 2.4e-15 56.7 3.1 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ84031.1 - 1.2e-20 71.6 7.5 2.5e-08 33.2 0.1 4.3 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 CDJ84031.1 - 3.6e-10 38.8 18.6 3.5e-06 26.2 0.1 5.1 5 1 0 5 5 5 3 EF hand EF-hand_9 PF14658.6 CDJ84031.1 - 4e-09 36.7 0.4 0.002 18.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CDJ84031.1 - 3.2e-06 27.0 2.8 0.016 15.1 0.1 2.7 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 CDJ84031.1 - 0.00012 22.1 4.8 0.026 14.5 0.3 2.6 1 1 1 2 2 2 2 Tellurite resistance protein TerB SPARC_Ca_bdg PF10591.9 CDJ84031.1 - 0.00038 20.8 2.6 0.011 16.1 1.8 2.5 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region p25-alpha PF05517.12 CDJ84031.1 - 0.001 19.2 4.9 0.075 13.2 0.5 2.6 1 1 2 3 3 3 2 p25-alpha EF-hand_10 PF14788.6 CDJ84031.1 - 0.0032 17.3 1.0 0.0032 17.3 1.0 2.9 3 0 0 3 3 3 1 EF hand TipAS PF07739.13 CDJ84031.1 - 0.0035 17.9 2.5 0.0085 16.6 0.4 2.3 2 1 0 2 2 2 1 TipAS antibiotic-recognition domain Ppx-GppA PF02541.16 CDJ84031.1 - 0.0038 16.7 0.3 0.14 11.6 0.2 2.0 1 1 0 2 2 2 1 Ppx/GppA phosphatase family EFhand_Ca_insen PF08726.10 CDJ84031.1 - 0.0041 17.2 0.9 0.0041 17.2 0.9 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand DUF3349 PF11829.8 CDJ84031.1 - 0.009 16.8 0.1 0.065 14.0 0.0 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF3349) Myb_DNA-binding PF00249.31 CDJ84031.1 - 0.016 15.4 1.7 0.69 10.2 0.1 2.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF3783 PF12646.7 CDJ84031.1 - 0.018 15.0 2.4 7.4 6.6 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF3783) UPF0154 PF03672.13 CDJ84031.1 - 0.021 14.8 0.3 6.4 6.9 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) DUF2608 PF11019.8 CDJ84031.1 - 0.034 13.6 0.5 0.14 11.7 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2608) Caleosin PF05042.13 CDJ84031.1 - 0.043 13.8 4.6 5.5 6.9 0.1 3.2 1 1 2 3 3 3 0 Caleosin related protein Phage_TAC_12 PF12363.8 CDJ84031.1 - 0.061 13.7 0.8 0.31 11.5 0.2 2.1 2 1 0 2 2 2 0 Phage tail assembly chaperone protein, TAC Cohesin PF00963.18 CDJ84031.1 - 0.071 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Cohesin domain RTX_C PF08339.10 CDJ84031.1 - 0.078 13.0 0.5 0.23 11.5 0.5 2.0 1 1 0 1 1 1 0 RTX C-terminal domain Dockerin_1 PF00404.18 CDJ84031.1 - 0.13 12.5 0.9 1.4 9.2 0.1 2.5 1 1 2 3 3 3 0 Dockerin type I domain GCS2 PF04107.13 CDJ84031.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) DUF5053 PF16476.5 CDJ84031.1 - 0.19 11.4 2.4 0.34 10.6 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5053) GlutR_dimer PF00745.20 CDJ84031.1 - 0.25 11.8 1.4 24 5.5 0.0 3.0 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain RNA_pol_Rpb4 PF03874.16 CDJ84031.1 - 0.28 11.5 3.7 0.57 10.5 0.1 2.4 2 1 0 2 2 2 0 RNA polymerase Rpb4 DUF327 PF03885.13 CDJ84031.1 - 2.4 8.1 7.1 3.9 7.4 1.5 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF327) Corona_S1 PF01600.16 CDJ84032.1 - 0.14 10.9 0.2 2.4 6.9 0.0 2.2 1 1 1 2 2 2 0 Coronavirus S1 glycoprotein Fil_haemagg PF05594.14 CDJ84032.1 - 0.86 10.2 6.3 3.6 8.2 0.9 2.3 2 0 0 2 2 2 0 Haemagluttinin repeat PIN_6 PF17146.4 CDJ84032.1 - 0.93 10.0 6.5 1.3e+02 3.1 0.1 4.0 3 1 1 4 4 4 0 PIN domain of ribonuclease Trans_reg_C PF00486.28 CDJ84034.1 - 0.016 15.3 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal ACBP PF00887.19 CDJ84035.1 - 1.4e-14 54.0 0.2 3.3e-14 52.9 0.2 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein zf-C2H2 PF00096.26 CDJ84035.1 - 1e-08 35.1 52.8 0.018 15.4 2.4 7.6 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ84035.1 - 1.4e-07 31.8 51.1 0.16 12.9 2.4 7.5 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CDJ84035.1 - 2.7e-05 24.4 34.5 0.0014 19.0 3.4 5.5 4 1 1 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CDJ84035.1 - 0.014 15.8 37.7 0.027 14.9 0.1 7.6 8 0 0 8 8 8 0 Zinc-finger of C2H2 type zf-WRNIP1_ubi PF18279.1 CDJ84035.1 - 0.041 14.5 1.2 0.14 12.8 0.0 2.7 2 0 0 2 2 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-Di19 PF05605.12 CDJ84035.1 - 0.054 13.8 0.0 0.054 13.8 0.0 6.8 7 0 0 7 7 7 0 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_ZHX PF18387.1 CDJ84035.1 - 0.13 11.9 22.2 0.13 11.9 0.6 5.3 5 0 0 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 CDJ84035.1 - 0.14 12.6 0.0 0.14 12.6 0.0 7.4 6 2 2 8 8 8 0 Zinc-finger double domain Lyase_8_N PF08124.11 CDJ84035.1 - 0.16 10.9 2.1 0.2 10.6 1.0 1.6 2 0 0 2 2 2 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Actin_micro PF17003.5 CDJ84035.1 - 0.42 9.7 18.0 0.48 9.5 0.1 4.9 1 1 1 2 2 1 0 Putative actin-like family zf-C2H2_jaz PF12171.8 CDJ84035.1 - 0.55 10.6 39.9 0.2 12.0 1.7 6.9 6 1 0 6 6 6 0 Zinc-finger double-stranded RNA-binding HypA PF01155.19 CDJ84035.1 - 6.8 6.8 10.1 6.4 6.8 1.3 3.9 3 2 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 2-oxoacid_dh PF00198.23 CDJ84036.1 - 5.5e-80 268.2 0.0 7.8e-80 267.7 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CDJ84036.1 - 1.3e-20 73.0 0.2 2.6e-20 72.0 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CDJ84036.1 - 7e-15 55.1 1.4 5.6e-14 52.2 0.5 2.5 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 CDJ84036.1 - 1.2e-05 25.0 1.2 0.0056 16.5 0.4 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 CDJ84036.1 - 0.00012 22.8 0.2 0.022 15.5 0.0 2.7 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_D23 PF16576.5 CDJ84036.1 - 0.011 15.0 0.6 0.025 13.8 0.6 1.6 1 1 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion FliT PF05400.13 CDJ84037.1 - 0.021 15.6 3.3 0.046 14.5 3.3 1.5 1 0 0 1 1 1 0 Flagellar protein FliT Bot1p PF12298.8 CDJ84037.1 - 0.054 13.7 2.2 0.087 13.0 2.2 1.3 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein HSP70 PF00012.20 CDJ84037.1 - 0.21 9.7 2.7 0.27 9.3 2.7 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF2252 PF10009.9 CDJ84038.1 - 0.07 12.2 1.1 0.087 11.9 1.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) BTB_3 PF16017.5 CDJ84038.1 - 0.13 12.3 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Mito_carr PF00153.27 CDJ84039.1 - 2.7e-63 209.9 3.6 1.3e-20 73.1 0.2 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein Activin_recp PF01064.23 CDJ84040.1 - 0.0016 19.5 13.0 0.0026 18.8 13.0 1.3 1 0 0 1 1 1 1 Activin types I and II receptor domain Toxin_TOLIP PF00087.21 CDJ84040.1 - 0.93 9.8 14.7 5.2 7.4 14.7 2.0 1 1 0 1 1 1 0 Snake toxin and toxin-like protein zf-C2H2_2 PF12756.7 CDJ84042.1 - 3.9e-26 91.3 26.4 2.2e-17 63.2 6.1 3.7 4 0 0 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 CDJ84042.1 - 3.7e-06 26.9 14.9 0.0043 17.0 0.8 4.7 4 0 0 4 4 4 2 BED zinc finger zf-C2H2_jaz PF12171.8 CDJ84042.1 - 0.0002 21.6 0.2 0.0002 21.6 0.2 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-HC5HC2H PF13771.6 CDJ84042.1 - 0.05 13.9 4.4 12 6.3 0.0 4.1 4 0 0 4 4 4 0 PHD-like zinc-binding domain zf-Di19 PF05605.12 CDJ84042.1 - 0.17 12.2 12.6 2.1 8.7 0.3 4.5 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding HNH_5 PF14279.6 CDJ84042.1 - 0.18 11.7 1.1 0.5 10.3 0.1 2.4 2 0 0 2 2 2 0 HNH endonuclease zf-C2H2_4 PF13894.6 CDJ84042.1 - 0.29 12.1 0.1 0.29 12.1 0.1 5.3 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDJ84042.1 - 3.2 7.9 6.4 0.77 9.8 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger GTP_EFTU PF00009.27 CDJ84043.1 - 2.6e-31 108.7 2.8 4.3e-29 101.5 2.8 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CDJ84043.1 - 6.5e-24 84.1 0.0 1.6e-23 82.8 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 CDJ84043.1 - 2.9e-10 40.2 0.1 8.5e-10 38.7 0.1 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ84043.1 - 7.6e-06 25.5 0.0 6.3e-05 22.6 0.1 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B PduV-EutP PF10662.9 CDJ84043.1 - 0.00065 19.5 0.1 0.004 16.9 0.1 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 CDJ84043.1 - 0.00092 18.8 0.0 0.0045 16.6 0.0 2.1 2 0 0 2 2 2 1 Ras family RsgA_GTPase PF03193.16 CDJ84043.1 - 0.0016 18.4 0.3 0.22 11.4 0.1 2.4 1 1 1 2 2 2 1 RsgA GTPase SRPRB PF09439.10 CDJ84043.1 - 0.0057 16.1 0.0 0.027 13.9 0.0 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 CDJ84043.1 - 0.012 15.8 0.0 0.038 14.2 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 CDJ84043.1 - 0.025 14.7 0.1 4.5 7.3 0.0 3.2 2 1 1 3 3 3 0 Dynamin family AAA_29 PF13555.6 CDJ84043.1 - 0.059 13.1 0.0 0.46 10.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain GvpL_GvpF PF06386.11 CDJ84043.1 - 0.26 11.2 5.6 1.7 8.5 0.3 2.4 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF AAA_23 PF13476.6 CDJ84043.1 - 1.3 9.4 0.0 1.3 9.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain LisH PF08513.11 CDJ84044.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 LisH DUF866 PF05907.13 CDJ84045.1 - 8.9e-18 64.7 0.2 1.8e-17 63.7 0.2 1.5 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) MMR_HSR1 PF01926.23 CDJ84045.1 - 1.4e-13 50.9 0.0 2.9e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP-bdg_N PF13167.6 CDJ84045.1 - 1.4e-11 44.9 0.0 3.1e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal GTP-bdg_M PF16360.5 CDJ84045.1 - 1.9e-05 25.1 0.1 4e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region AAA_16 PF13191.6 CDJ84045.1 - 0.045 14.1 0.0 0.09 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 CDJ84045.1 - 0.13 11.8 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF1779 PF08680.10 CDJ84045.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 TATA-box binding CAP PF00188.26 CDJ84046.1 - 2.3e-11 44.6 0.3 3.1e-11 44.2 0.3 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CDJ84047.1 - 1.6e-21 77.4 1.6 3.1e-12 47.4 0.1 2.6 2 0 0 2 2 2 2 Cysteine-rich secretory protein family Mucin PF01456.17 CDJ84047.1 - 4.1 7.4 31.4 3.5 7.6 9.8 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Sina PF03145.16 CDJ84048.1 - 0.0065 16.4 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 Seven in absentia protein family 7TM_GPCR_Srsx PF10320.9 CDJ84049.1 - 1.3e-11 44.4 4.2 2e-11 43.8 4.2 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx GWT1 PF06423.12 CDJ84049.1 - 0.25 11.5 3.4 0.2 11.8 1.5 1.6 1 1 1 2 2 2 0 GWT1 7TM_GPCR_Srsx PF10320.9 CDJ84050.1 - 8.2e-25 87.6 8.1 1e-24 87.3 8.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 CDJ84050.1 - 3.5e-06 26.5 6.0 5.1e-06 26.0 6.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srbc PF10316.9 CDJ84050.1 - 0.034 13.7 13.3 0.04 13.4 13.3 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srbc RELT PF12606.8 CDJ84050.1 - 2 7.5 9.3 0.2 10.7 0.6 2.6 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 Glyco_hydro_20 PF00728.22 CDJ84051.1 - 1.6e-07 31.0 0.0 2.2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain AP_endonuc_2 PF01261.24 CDJ84051.1 - 0.016 14.6 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Peptidase_M10 PF00413.24 CDJ84053.1 - 5.3e-49 166.1 0.0 9.1e-49 165.3 0.0 1.4 1 0 0 1 1 1 1 Matrixin Glyco_hydro_20 PF00728.22 CDJ84053.1 - 5.8e-12 45.7 0.2 1.1e-11 44.7 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain PG_binding_1 PF01471.18 CDJ84053.1 - 1.1e-08 35.2 0.0 2.4e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Hemopexin PF00045.19 CDJ84053.1 - 5.6e-05 23.0 1.3 0.21 11.6 0.1 3.7 3 0 0 3 3 3 2 Hemopexin AP_endonuc_2 PF01261.24 CDJ84053.1 - 0.00082 18.9 0.1 0.003 17.0 0.0 1.9 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Reprolysin_4 PF13583.6 CDJ84053.1 - 0.031 13.9 0.0 0.079 12.6 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 CDJ84053.1 - 0.047 14.2 0.0 0.16 12.5 0.0 2.0 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CDJ84053.1 - 0.17 12.0 0.2 0.36 11.0 0.2 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 TMEM171 PF15471.6 CDJ84054.1 - 0.023 13.7 0.1 0.023 13.7 0.1 2.0 3 0 0 3 3 3 0 Transmembrane protein family 171 Orai-1 PF07856.12 CDJ84054.1 - 0.067 12.9 0.2 0.1 12.3 0.2 1.2 1 0 0 1 1 1 0 Mediator of CRAC channel activity Nucleoside_tran PF01733.18 CDJ84054.1 - 0.076 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Nucleoside transporter PRT_C PF08372.10 CDJ84054.1 - 0.091 12.5 0.2 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Shisa PF13908.6 CDJ84054.1 - 2.7 8.2 7.1 0.59 10.4 0.5 2.3 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator Rho_GDI PF02115.17 CDJ84055.1 - 3.9e-30 105.1 1.4 4.7e-30 104.8 0.1 1.7 2 1 0 2 2 2 1 RHO protein GDP dissociation inhibitor HIP1_clath_bdg PF16515.5 CDJ84055.1 - 0.27 11.9 6.6 2.9 8.5 0.8 2.6 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 G-alpha PF00503.20 CDJ84056.1 - 8.6e-104 347.5 2.1 1.1e-103 347.2 2.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDJ84056.1 - 1e-17 64.2 0.5 1.1e-13 51.0 0.1 2.9 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ84056.1 - 3.6e-06 26.5 0.9 0.00048 19.5 0.3 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 CDJ84056.1 - 0.0012 19.0 1.2 1.5 9.1 0.0 2.9 3 1 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 CDJ84056.1 - 0.026 13.9 0.1 0.047 13.1 0.1 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 CDJ84056.1 - 0.19 11.5 0.0 0.49 10.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain T-box PF00907.22 CDJ84057.1 - 4.7e-75 251.9 0.0 6.6e-75 251.4 0.0 1.2 1 0 0 1 1 1 1 T-box Glyco_transf_10 PF00852.19 CDJ84058.1 - 5.6e-50 169.5 0.2 7.8e-50 169.0 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CDJ84058.1 - 3.9e-22 78.8 0.1 8e-22 77.8 0.1 1.6 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal NST1 PF13945.6 CDJ84059.1 - 0.054 13.6 0.1 0.083 13.0 0.1 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator 7TM_GPCR_Srab PF10292.9 CDJ84061.1 - 0.00025 20.1 1.5 0.00039 19.5 1.5 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor Sre PF03125.18 CDJ84061.1 - 0.013 14.7 3.9 0.036 13.2 3.7 1.7 1 1 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor SpoIIIAH PF12685.7 CDJ84062.1 - 0.00012 22.0 3.2 0.00012 22.0 3.2 2.6 2 1 0 2 2 1 1 SpoIIIAH-like protein TMEM154 PF15102.6 CDJ84062.1 - 0.0026 17.7 0.0 0.0026 17.7 0.0 3.6 2 1 1 3 3 2 1 TMEM154 protein family ABC_export PF16962.5 CDJ84062.1 - 0.0026 16.3 2.0 0.0036 15.8 2.0 1.2 1 0 0 1 1 1 1 Putative ABC exporter Mucin PF01456.17 CDJ84062.1 - 0.004 17.2 46.6 0.0056 16.7 26.9 3.1 2 1 1 3 3 3 2 Mucin-like glycoprotein AF-4 PF05110.13 CDJ84062.1 - 0.0044 15.2 23.6 0.0053 14.9 23.6 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein HemX PF04375.14 CDJ84062.1 - 0.0089 15.3 0.2 0.0089 15.3 0.2 1.6 2 0 0 2 2 2 1 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4366 PF14283.6 CDJ84062.1 - 0.019 15.0 0.1 0.019 15.0 0.1 3.3 2 1 1 3 3 2 0 Domain of unknown function (DUF4366) TrbL PF04610.14 CDJ84062.1 - 0.095 12.4 0.5 0.13 12.0 0.5 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein DUF5383 PF17355.2 CDJ84062.1 - 0.19 12.1 0.0 0.19 12.1 0.0 3.2 3 0 0 3 3 2 0 Family of unknown function (DUF5383) TRP PF06011.12 CDJ84062.1 - 0.22 10.2 2.3 0.21 10.3 1.4 1.4 1 1 0 1 1 1 0 Transient receptor potential (TRP) ion channel Orf78 PF06024.12 CDJ84062.1 - 1.4 9.2 0.0 1.4 9.2 0.0 3.1 3 0 0 3 3 3 0 Orf78 (ac78) CLN3 PF02487.17 CDJ84062.1 - 1.4 7.8 7.6 0.16 11.0 0.4 2.1 2 0 0 2 2 2 0 CLN3 protein V_ATPase_I PF01496.19 CDJ84062.1 - 2.6 5.9 11.2 0.028 12.4 1.2 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family SID-1_RNA_chan PF13965.6 CDJ84062.1 - 2.8 6.3 3.8 0.69 8.2 0.1 1.7 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Connexin PF00029.19 CDJ84062.1 - 3.2 7.5 15.5 2.3 7.9 9.2 2.5 2 1 0 2 2 2 0 Connexin zf-C2H2_10 PF16588.5 CDJ84063.1 - 0.37 10.6 8.3 2.3 8.1 2.5 2.6 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_4 PF14392.6 CDJ84063.1 - 3.4 7.5 11.7 0.67 9.7 2.7 2.4 2 0 0 2 2 2 0 Zinc knuckle DEAD PF00270.29 CDJ84064.1 - 6.5e-44 149.8 0.2 9.9e-44 149.2 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ84064.1 - 9.8e-30 103.2 2.2 3.5e-29 101.4 1.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ84064.1 - 0.0011 19.0 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CDJ84064.1 - 0.0016 17.7 0.2 0.0024 17.1 0.2 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 CDJ84064.1 - 0.0054 16.1 0.1 0.012 15.0 0.1 1.6 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Terminase_3 PF04466.13 CDJ84064.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Phage terminase large subunit Fringe PF02434.16 CDJ84065.1 - 1.9e-14 53.7 0.5 1.2e-13 51.2 0.5 1.9 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 CDJ84065.1 - 0.00028 20.8 0.1 0.029 14.2 0.2 2.3 1 1 1 2 2 2 2 Galactosyltransferase Peptidase_S10 PF00450.22 CDJ84066.1 - 0 1412.1 45.4 7.8e-118 394.5 5.7 5.0 4 1 0 4 4 4 4 Serine carboxypeptidase Abhydrolase_6 PF12697.7 CDJ84066.1 - 7.4e-08 33.3 0.0 0.097 13.3 0.0 7.0 7 1 0 7 7 7 1 Alpha/beta hydrolase family zf-HYPF PF07503.12 CDJ84066.1 - 0.092 12.5 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 HypF finger Glyoxalase_2 PF12681.7 CDJ84066.1 - 0.12 12.3 0.5 2.9 7.8 0.1 2.5 2 0 0 2 2 2 0 Glyoxalase-like domain DUF4728 PF15860.5 CDJ84067.1 - 1.8 9.3 15.3 0.17 12.6 11.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4728) ATP1G1_PLM_MAT8 PF02038.16 CDJ84067.1 - 6.5 6.3 6.8 2.2 7.8 0.4 2.5 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family DUF2079 PF09852.9 CDJ84069.1 - 0.16 10.8 10.0 0.2 10.5 10.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) DUF3382 PF11862.8 CDJ84069.1 - 2.4 8.5 9.2 0.58 10.5 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) DUF2070 PF09843.9 CDJ84069.1 - 7 4.8 16.4 9.1 4.4 16.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RVT_1 PF00078.27 CDJ84070.1 - 6.6e-15 55.2 0.0 1.1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CDJ84071.1 - 1.3e-08 34.7 0.0 4.3e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) HNH PF01844.23 CDJ84071.1 - 0.058 13.6 0.0 15 5.9 0.0 2.6 2 0 0 2 2 2 0 HNH endonuclease DUF3561 PF12084.8 CDJ84072.1 - 0.063 13.3 6.1 0.083 12.9 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3561) DUF1430 PF07242.11 CDJ84072.1 - 9.2 6.6 16.9 1.8 8.8 12.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1430) PHO4 PF01384.20 CDJ84073.1 - 4.8 6.1 16.0 5.3 6.0 16.0 1.0 1 0 0 1 1 1 0 Phosphate transporter family DUF2157 PF09925.9 CDJ84074.1 - 0.016 15.0 8.2 0.12 12.1 8.2 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) YfhO PF09586.10 CDJ84074.1 - 0.45 8.7 7.4 0.58 8.3 7.4 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO BrnA_antitoxin PF14384.6 CDJ84076.1 - 0.053 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 BrnA antitoxin of type II toxin-antitoxin system Ndr PF03096.14 CDJ84079.1 - 1e-92 309.9 0.6 1.2e-92 309.6 0.6 1.0 1 0 0 1 1 1 1 Ndr family ACP_syn_III PF08545.10 CDJ84079.1 - 0.0029 17.4 0.0 0.012 15.4 0.0 2.1 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Abhydrolase_1 PF00561.20 CDJ84079.1 - 0.027 14.1 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 CDJ84079.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Protocadherin PF08374.11 CDJ84080.1 - 0.27 11.2 1.4 0.97 9.4 0.0 2.1 1 1 0 2 2 2 0 Protocadherin FixS PF03597.15 CDJ84080.1 - 0.27 10.9 0.1 0.27 10.9 0.1 2.8 4 0 0 4 4 4 0 Cytochrome oxidase maturation protein cbb3-type Vma12 PF11712.8 CDJ84080.1 - 0.95 9.5 6.2 0.74 9.9 0.3 2.3 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Mtp PF03821.16 CDJ84080.1 - 2.6 7.6 6.7 3 7.4 0.6 2.2 1 1 1 2 2 2 0 Golgi 4-transmembrane spanning transporter TPR_2 PF07719.17 CDJ84083.1 - 4.2e-36 120.1 22.1 3.3e-05 23.7 0.0 11.0 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ84083.1 - 2e-35 119.2 29.5 8e-08 31.8 0.2 10.3 10 1 0 10 10 10 6 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ84083.1 - 8.3e-30 100.6 14.2 0.00022 21.0 0.0 9.8 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ84083.1 - 1.8e-28 98.6 23.8 5.1e-09 36.3 0.0 7.8 5 3 1 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ84083.1 - 1.5e-26 90.4 30.7 6.9e-05 22.7 0.0 10.3 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ84083.1 - 1.2e-23 82.1 19.9 0.00063 20.2 0.1 10.6 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ84083.1 - 6.7e-20 70.1 12.2 0.00014 22.4 0.1 10.1 7 3 4 11 11 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ84083.1 - 6.9e-19 68.2 13.6 0.00016 22.3 0.2 7.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ84083.1 - 1.4e-15 57.6 22.1 0.00082 19.8 0.7 7.4 4 3 6 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ84083.1 - 1.2e-14 53.7 26.1 0.00054 19.6 3.3 7.6 6 1 2 8 8 7 4 TPR repeat ANAPC3 PF12895.7 CDJ84083.1 - 7.4e-14 51.7 15.9 1.3e-05 25.3 4.3 5.4 5 2 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CDJ84083.1 - 3.2e-08 33.2 32.2 0.21 11.5 0.0 9.7 12 1 0 12 12 10 3 Tetratricopeptide repeat TPR_MalT PF17874.1 CDJ84083.1 - 7.4e-08 32.1 4.5 0.1 11.9 0.0 4.0 3 1 1 4 4 4 3 MalT-like TPR region TPR_17 PF13431.6 CDJ84083.1 - 4.4e-07 29.8 29.3 0.31 11.5 0.9 9.5 9 1 1 10 10 10 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ84083.1 - 5e-07 29.8 1.6 3.1 8.0 0.0 6.0 4 2 2 6 6 5 1 Tetratricopeptide repeat DUF3808 PF10300.9 CDJ84083.1 - 2.7e-06 26.4 1.8 4e-06 25.9 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3808) TPR_15 PF13429.6 CDJ84083.1 - 4e-06 26.2 6.6 3.1e-05 23.3 1.9 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_5 PF12688.7 CDJ84083.1 - 9.6e-06 25.8 0.1 0.067 13.4 0.0 4.1 3 1 0 4 4 4 1 Tetratrico peptide repeat TPR_4 PF07721.14 CDJ84083.1 - 1.1e-05 25.6 6.3 0.72 10.7 0.0 5.4 5 0 0 5 5 4 1 Tetratricopeptide repeat Coatomer_E PF04733.14 CDJ84083.1 - 2.6e-05 23.8 9.8 0.001 18.6 2.0 3.7 4 0 0 4 4 4 2 Coatomer epsilon subunit MIT PF04212.18 CDJ84083.1 - 3.4e-05 23.8 13.9 1.7 8.8 0.0 6.9 7 0 0 7 7 5 1 MIT (microtubule interacting and transport) domain TPR_21 PF09976.9 CDJ84083.1 - 4.6e-05 23.2 17.2 0.00025 20.8 6.3 3.5 4 1 0 4 4 3 2 Tetratricopeptide repeat-like domain PPR PF01535.20 CDJ84083.1 - 0.00016 21.7 8.0 3.9 8.0 0.1 6.2 7 0 0 7 7 5 1 PPR repeat TPR_3 PF07720.12 CDJ84083.1 - 0.0003 20.7 26.8 1.4 9.0 0.8 8.5 9 0 0 9 9 9 2 Tetratricopeptide repeat Sel1 PF08238.12 CDJ84083.1 - 0.00093 19.8 15.8 0.32 11.7 0.1 7.0 7 0 0 7 7 7 1 Sel1 repeat RPN7 PF10602.9 CDJ84083.1 - 0.001 18.8 18.5 0.056 13.1 0.3 6.0 2 2 3 6 6 6 2 26S proteasome subunit RPN7 TPR_20 PF14561.6 CDJ84083.1 - 0.0022 18.3 8.3 3.4 8.0 0.1 5.6 4 1 2 6 6 6 1 Tetratricopeptide repeat DUF4919 PF16266.5 CDJ84083.1 - 0.0025 17.8 6.3 0.73 9.8 0.2 4.4 2 1 3 5 5 5 1 Domain of unknown function (DUF4919) HrpB1_HrpK PF09613.10 CDJ84083.1 - 0.0032 17.1 0.8 20 4.8 0.1 4.6 5 1 1 6 6 5 0 Bacterial type III secretion protein (HrpB1_HrpK) Rapsyn_N PF10579.9 CDJ84083.1 - 0.018 15.1 0.5 0.29 11.3 0.0 2.9 3 0 0 3 3 2 0 Rapsyn N-terminal myristoylation and linker region NARP1 PF12569.8 CDJ84083.1 - 0.026 13.4 19.6 0.044 12.7 0.8 5.2 3 2 4 7 7 7 0 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.6 CDJ84083.1 - 0.048 13.7 10.9 6.2 7.0 0.0 5.4 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Wzy_C_2 PF11846.8 CDJ84083.1 - 0.14 12.0 1.3 0.78 9.6 0.1 2.7 3 0 0 3 3 2 0 Virulence factor membrane-bound polymerase, C-terminal Ribosomal_L12 PF00542.19 CDJ84083.1 - 0.16 12.3 0.0 0.61 10.5 0.0 1.9 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain MethyltransfD12 PF02086.15 CDJ84083.1 - 1.6 8.3 8.8 0.12 12.1 1.3 2.3 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase PPR_2 PF13041.6 CDJ84083.1 - 3.4 8.0 10.7 1.7e+02 2.5 0.1 5.9 6 1 0 6 6 5 0 PPR repeat family PRIMA1 PF16101.5 CDJ84085.1 - 0.36 10.9 5.3 0.48 10.5 5.3 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Sec66 PF09802.9 CDJ84086.1 - 0.04 13.5 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 Peptidase_M90 PF06167.12 CDJ84086.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 7TM_GPCR_Srsx PF10320.9 CDJ84088.1 - 2.9e-26 92.4 21.0 3.6e-26 92.1 21.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 CDJ84088.1 - 7.7e-11 41.8 14.2 9.9e-11 41.5 14.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) AMOP PF03782.17 CDJ84089.1 - 1.8e-46 157.8 7.3 4e-46 156.7 7.3 1.6 1 0 0 1 1 1 1 AMOP domain NIDO PF06119.14 CDJ84089.1 - 4.3e-05 24.4 0.1 0.00029 21.7 0.0 2.5 2 0 0 2 2 2 1 Nidogen-like LEP503 PF15221.6 CDJ84089.1 - 0.16 12.4 4.4 0.39 11.1 2.6 2.3 2 0 0 2 2 2 0 Lens epithelial cell protein LEP503 Hormone_recep PF00104.30 CDJ84090.1 - 3e-06 27.0 0.1 5.6e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor MatB PF16449.5 CDJ84090.1 - 0.17 11.7 0.1 0.43 10.4 0.1 1.7 1 0 0 1 1 1 0 Fimbrillin MatB PID PF00640.23 CDJ84091.1 - 1.1e-09 38.4 0.2 3.4e-09 36.9 0.1 1.7 1 1 1 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) DUF4571 PF15137.6 CDJ84091.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4571) SET PF00856.28 CDJ84092.1 - 4.5e-11 43.4 1.8 4.5e-11 43.4 1.8 2.6 2 1 0 2 2 2 1 SET domain preSET_CXC PF18264.1 CDJ84092.1 - 5.9e-10 39.5 21.5 5.9e-10 39.5 21.5 2.8 2 1 0 2 2 2 1 CXC domain TCR PF03638.15 CDJ84092.1 - 4.8 7.6 34.5 0.28 11.5 15.9 2.9 2 0 0 2 2 2 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain RhoGAP PF00620.27 CDJ84094.1 - 3.4e-49 166.6 0.1 5.9e-49 165.8 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain Auto_anti-p27 PF06677.12 CDJ84095.1 - 7.7 6.8 6.9 1.1 9.5 1.8 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) SNF5 PF04855.12 CDJ84096.1 - 2.9e-53 181.1 0.0 4.5e-29 101.9 0.0 2.1 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 RRM_1 PF00076.22 CDJ84097.1 - 4.9e-20 71.1 0.2 8e-20 70.4 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ84097.1 - 6.2e-05 22.6 0.0 8.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ84097.1 - 0.00018 21.3 0.0 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 CDJ84097.1 - 0.0011 19.0 0.1 0.0022 18.0 0.1 1.5 1 0 0 1 1 1 1 RNA binding motif Limkain-b1 PF11608.8 CDJ84097.1 - 0.042 13.9 0.0 0.083 13.0 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 AhpC-TSA PF00578.21 CDJ84098.1 - 1.8e-36 124.8 0.0 4.4e-36 123.5 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA family DUF1604 PF07713.13 CDJ84098.1 - 3.7e-34 116.4 1.0 3.7e-34 116.4 1.0 3.5 3 1 0 3 3 3 1 Protein of unknown function (DUF1604) Redoxin PF08534.10 CDJ84098.1 - 1.3e-13 50.9 0.0 2.7e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CDJ84098.1 - 8.4e-09 35.1 0.0 2.4e-08 33.7 0.0 1.9 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin G-patch PF01585.23 CDJ84098.1 - 4.1e-07 29.8 0.1 1e-06 28.5 0.1 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CDJ84098.1 - 0.024 14.7 0.1 0.024 14.7 0.1 3.1 3 0 0 3 3 3 0 G-patch domain SRP-alpha_N PF04086.13 CDJ84098.1 - 0.6 10.0 31.4 1.7 8.5 31.4 1.8 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Miga PF10265.9 CDJ84098.1 - 1.8 7.4 9.9 3.5 6.5 9.9 1.4 1 0 0 1 1 1 0 Mitoguardin Pex14_N PF04695.13 CDJ84098.1 - 4.1 8.0 13.3 9.2 6.9 3.8 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AP3D1 PF06375.11 CDJ84098.1 - 6.1 7.1 42.6 1.6 8.9 21.5 3.1 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Anticodon_1 PF08264.13 CDJ84100.1 - 3.1e-05 24.0 0.0 3.4e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DENN PF02141.21 CDJ84103.1 - 9.4e-25 87.6 6.5 1.6e-24 86.9 6.5 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain 3HCDH_N PF02737.18 CDJ84104.1 - 1.9e-50 171.2 2.5 4.3e-50 170.1 2.5 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 CDJ84104.1 - 1.9e-39 135.5 0.2 4.2e-39 134.4 0.2 1.6 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 CDJ84104.1 - 1.1e-34 118.9 0.0 8.5e-24 84.0 0.0 3.3 3 1 1 4 4 4 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 CDJ84104.1 - 7.2e-27 94.8 0.2 1.3e-26 93.9 0.2 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NAD_Gly3P_dh_N PF01210.23 CDJ84104.1 - 2.7e-07 30.7 0.4 7.4e-07 29.3 0.4 1.7 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 CDJ84104.1 - 0.002 17.8 0.9 0.0039 16.8 0.9 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 CDJ84104.1 - 0.0052 17.0 1.5 0.015 15.5 0.6 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 CDJ84104.1 - 0.084 13.5 0.4 0.32 11.6 0.4 2.1 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.27 CDJ84104.1 - 0.9 10.1 3.2 0.85 10.2 0.3 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase zf-nanos PF05741.13 CDJ84105.1 - 8.1e-17 61.2 8.0 1.1e-16 60.8 8.0 1.2 1 0 0 1 1 1 1 Nanos RNA binding domain zf-ribbon_3 PF13248.6 CDJ84105.1 - 0.0032 16.8 3.3 0.097 12.1 0.7 3.2 3 0 0 3 3 3 1 zinc-ribbon domain SEA PF01390.20 CDJ84107.1 - 1.3e-10 41.3 0.1 1.3e-10 41.3 0.1 1.9 2 0 0 2 2 2 1 SEA domain Trypan_PARP PF05887.11 CDJ84107.1 - 0.0026 17.7 45.2 0.0026 17.7 45.2 5.2 3 1 2 5 5 5 3 Procyclic acidic repetitive protein (PARP) Amnionless PF14828.6 CDJ84107.1 - 0.067 12.0 0.2 0.1 11.4 0.2 1.3 1 0 0 1 1 1 0 Amnionless PulG PF11773.8 CDJ84107.1 - 0.069 13.0 0.2 0.15 11.9 0.2 1.5 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin HMG_box PF00505.19 CDJ84108.1 - 2.2e-25 88.9 1.3 4.7e-25 87.8 1.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ84108.1 - 3.4e-09 37.2 0.9 9.1e-09 35.8 0.9 1.8 1 0 0 1 1 1 1 HMG-box domain Tubulin_C PF03953.17 CDJ84109.1 - 6e-48 162.2 0.0 9.6e-48 161.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 CDJ84109.1 - 4e-28 99.0 0.0 6.9e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 CDJ84109.1 - 0.0037 17.0 0.0 0.0079 15.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain DnaB_C PF03796.15 CDJ84110.1 - 4.9e-18 65.4 0.0 1.8e-17 63.5 0.0 1.8 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_25 PF13481.6 CDJ84110.1 - 5.2e-16 58.8 0.0 1.1e-15 57.7 0.0 1.5 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 CDJ84110.1 - 5.1e-10 39.1 0.0 1e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 KaiC T2SSE PF00437.20 CDJ84110.1 - 1.9e-05 23.9 0.4 0.0033 16.5 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.6 CDJ84110.1 - 4.6e-05 23.7 0.1 0.00025 21.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CDJ84110.1 - 0.00023 20.9 0.1 0.0004 20.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain NTPase_P4 PF11602.8 CDJ84110.1 - 0.0011 18.3 0.2 0.33 10.1 0.0 2.2 2 0 0 2 2 2 2 ATPase P4 of dsRNA bacteriophage phi-12 AAA_23 PF13476.6 CDJ84110.1 - 0.0026 18.3 4.1 0.0037 17.8 2.6 2.1 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.6 CDJ84110.1 - 0.0082 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 CDJ84110.1 - 0.023 15.2 2.8 0.023 15.2 0.7 2.0 2 1 1 3 3 3 0 ABC transporter cobW PF02492.19 CDJ84110.1 - 0.038 13.6 0.3 0.081 12.5 0.3 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.12 CDJ84110.1 - 0.044 13.2 1.8 0.05 13.1 0.1 1.9 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_16 PF13191.6 CDJ84110.1 - 0.061 13.7 0.0 0.16 12.4 0.0 1.7 2 1 0 2 2 1 0 AAA ATPase domain NACHT PF05729.12 CDJ84110.1 - 0.074 13.0 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 NACHT domain SMP_C2CD2L PF18696.1 CDJ84110.1 - 0.11 12.3 0.2 0.19 11.5 0.2 1.3 1 0 0 1 1 1 0 Synaptotagmin-like, mitochondrial and lipid-binding domain AAA_30 PF13604.6 CDJ84110.1 - 0.12 12.1 0.1 0.23 11.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CDJ84110.1 - 0.13 11.6 1.4 1.2 8.4 0.0 2.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_19 PF13245.6 CDJ84110.1 - 0.46 10.8 1.7 1.3 9.3 1.7 1.8 1 1 0 1 1 1 0 AAA domain Exo_endo_phos_2 PF14529.6 CDJ84111.1 - 0.097 12.5 0.0 0.3 10.9 0.0 1.7 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Myosin_head PF00063.21 CDJ84112.1 - 8e-93 311.9 0.0 2.2e-92 310.4 0.0 1.8 2 0 0 2 2 2 1 Myosin head (motor domain) PDZ_6 PF17820.1 CDJ84112.1 - 9e-08 31.8 0.3 6.1e-07 29.2 0.1 2.6 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 CDJ84112.1 - 6.4e-07 29.6 0.0 2e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 PDZ domain AAA_22 PF13401.6 CDJ84112.1 - 0.0044 17.3 0.0 0.0044 17.3 0.0 4.9 4 1 0 4 4 3 1 AAA domain PDZ_2 PF13180.6 CDJ84112.1 - 0.059 13.7 0.0 0.24 11.7 0.0 2.0 1 0 0 1 1 1 0 PDZ domain Myosin_tail_1 PF01576.19 CDJ84112.1 - 0.073 10.9 128.9 0.0028 15.6 60.8 3.9 1 1 3 4 4 4 0 Myosin tail AAA_19 PF13245.6 CDJ84112.1 - 0.074 13.4 0.0 0.074 13.4 0.0 3.9 4 1 0 4 4 4 0 AAA domain Filament PF00038.21 CDJ84112.1 - 0.34 10.5 114.6 0.055 13.1 6.8 6.1 2 1 2 4 4 4 0 Intermediate filament protein PRK PF00485.18 CDJ84112.1 - 0.38 10.5 0.0 0.38 10.5 0.0 2.6 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family RsgA_GTPase PF03193.16 CDJ84112.1 - 0.8 9.6 0.0 0.8 9.6 0.0 3.1 3 0 0 3 3 3 0 RsgA GTPase DUF4250 PF14056.6 CDJ84112.1 - 9.3 6.3 9.3 19 5.3 0.3 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4250) Vps26 PF03643.15 CDJ84113.1 - 1.3e-127 424.5 2.7 1.5e-127 424.3 2.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.22 CDJ84113.1 - 0.00058 20.3 0.1 0.13 12.7 0.0 3.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CDJ84113.1 - 0.006 16.6 1.0 0.25 11.4 0.2 3.4 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain AAA_28 PF13521.6 CDJ84114.1 - 2.1e-20 73.6 0.1 4e-20 72.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 CDJ84114.1 - 0.075 12.0 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TRP_N PF14558.6 CDJ84116.1 - 0.059 13.7 0.1 0.15 12.4 0.1 1.8 1 1 0 1 1 1 0 ML-like domain Meckelin PF09773.9 CDJ84117.1 - 4.3e-210 700.0 0.6 5.8e-210 699.5 0.6 1.2 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) Filamin PF00630.19 CDJ84118.1 - 2.4e-107 352.7 10.0 6.1e-17 62.3 0.1 10.8 11 0 0 11 11 11 9 Filamin/ABP280 repeat Y_Y_Y PF07495.13 CDJ84118.1 - 1.5e-05 24.8 0.1 5.5 7.0 0.1 5.4 7 0 0 7 7 7 3 Y_Y_Y domain PapC_N PF13954.6 CDJ84118.1 - 2.1e-05 24.6 0.0 1.1 9.2 0.0 5.1 6 0 0 6 6 6 2 PapC N-terminal domain 7tm_1 PF00001.21 CDJ84119.1 - 0.00058 19.3 16.7 0.00058 19.3 16.7 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4690 PF15756.5 CDJ84119.1 - 0.16 12.5 2.0 10 6.8 0.1 2.7 2 0 0 2 2 2 0 Small Novel Rich in Cartilage MscL PF01741.18 CDJ84119.1 - 4.8 7.5 6.9 0.53 10.6 0.4 2.3 2 1 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL SUKH-4 PF14435.6 CDJ84120.1 - 0.057 13.5 0.0 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 SUKH-4 immunity protein DM PF00751.18 CDJ84121.1 - 3e-13 49.5 5.0 4.6e-13 48.8 5.0 1.2 1 0 0 1 1 1 1 DM DNA binding domain CpXC PF14353.6 CDJ84121.1 - 0.085 12.9 0.7 2.7 8.0 0.1 2.3 2 0 0 2 2 2 0 CpXC protein PAN_1 PF00024.26 CDJ84123.1 - 1.1 9.2 5.0 0.24 11.4 0.2 2.4 2 0 0 2 2 2 0 PAN domain CathepsinC_exc PF08773.11 CDJ84124.1 - 0.039 14.2 0.3 0.081 13.2 0.0 1.7 1 1 1 2 2 2 0 Cathepsin C exclusion domain DOMON PF03351.17 CDJ84126.1 - 1.4e-06 28.5 0.0 1.4e-06 28.5 0.0 2.4 3 0 0 3 3 3 1 DOMON domain zf-C4 PF00105.18 CDJ84127.1 - 5.3e-27 94.1 15.1 5.3e-27 94.1 15.1 1.6 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ84127.1 - 1.2e-07 31.5 0.3 2.3e-07 30.6 0.3 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor ThiF PF00899.21 CDJ84128.1 - 5.2e-70 235.6 0.0 6.9e-70 235.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 CDJ84128.1 - 9e-21 74.3 0.2 1.8e-20 73.3 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 CDJ84128.1 - 8.1e-07 29.2 0.4 0.00016 21.7 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 CDJ84128.1 - 5.6e-06 26.7 0.0 1.5e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 CDJ84128.1 - 0.00073 19.6 0.6 0.0022 18.1 0.1 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 CDJ84128.1 - 0.0087 16.6 0.0 0.022 15.3 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CDJ84128.1 - 0.014 14.7 0.0 0.039 13.2 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 CDJ84128.1 - 0.082 13.2 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 CDJ84128.1 - 0.092 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 CDJ84128.1 - 0.14 12.5 0.1 0.64 10.3 0.1 2.2 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain CLN3 PF02487.17 CDJ84129.1 - 1.7e-122 409.3 18.0 2.3e-122 408.9 18.0 1.2 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 CDJ84129.1 - 0.0063 15.5 24.9 2.6 6.9 20.5 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DDE_Tnp_1_7 PF13843.6 CDJ84129.1 - 0.013 14.8 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Transposase IS4 DUF1035 PF06281.12 CDJ84129.1 - 0.019 15.0 0.2 0.019 15.0 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1035) CLN3 PF02487.17 CDJ84130.1 - 5.7e-124 414.2 10.1 1e-123 413.4 10.1 1.4 1 1 0 1 1 1 1 CLN3 protein DUF1035 PF06281.12 CDJ84130.1 - 0.0034 17.4 0.2 0.014 15.4 0.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1035) P66_CC PF16563.5 CDJ84131.1 - 2e-10 40.1 8.3 2e-10 40.1 8.3 2.6 3 0 0 3 3 3 1 Coiled-coil and interaction region of P66A and P66B with MBD2 RIP PF00161.19 CDJ84131.1 - 0.012 15.2 0.0 0.012 15.2 0.0 2.7 2 0 0 2 2 2 0 Ribosome inactivating protein Zn-ribbon_8 PF09723.10 CDJ84131.1 - 0.04 14.0 0.6 0.087 13.0 0.6 1.6 1 0 0 1 1 1 0 Zinc ribbon domain GATA PF00320.27 CDJ84131.1 - 0.49 10.0 4.5 0.14 11.7 1.3 1.8 2 0 0 2 2 2 0 GATA zinc finger Arrestin_N PF00339.29 CDJ84134.1 - 1e-39 135.9 0.0 1.2e-39 135.7 0.0 1.0 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CDJ84134.1 - 0.0005 20.5 0.0 0.0007 20.1 0.0 1.2 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain DUF922 PF06037.11 CDJ84134.1 - 0.015 15.1 0.3 0.019 14.8 0.3 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) Vps26 PF03643.15 CDJ84134.1 - 0.02 13.9 0.0 0.045 12.7 0.0 1.5 1 1 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 Rgp1 PF08737.10 CDJ84134.1 - 0.062 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Rgp1 DUF2722 PF10846.8 CDJ84135.1 - 6.4 5.6 9.0 1.6 7.6 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Y_phosphatase PF00102.27 CDJ84136.1 - 1.7e-36 126.0 0.0 2.4e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CDJ84136.1 - 0.00096 19.2 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CDJ84136.1 - 0.002 17.9 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CDJ84136.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate EMP24_GP25L PF01105.24 CDJ84137.1 - 6.9e-48 163.0 0.2 7.9e-48 162.8 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD FCD PF07729.12 CDJ84137.1 - 0.01 16.2 0.1 0.014 15.8 0.1 1.2 1 0 0 1 1 1 0 FCD domain Innexin PF00876.18 CDJ84137.1 - 0.015 14.6 0.4 0.021 14.1 0.4 1.3 1 1 0 1 1 1 0 Innexin SdrD_B PF17210.3 CDJ84137.1 - 0.054 13.7 0.3 0.11 12.7 0.3 1.6 1 1 0 1 1 1 0 SdrD B-like domain Gam PF06064.11 CDJ84138.1 - 0.079 13.2 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Host-nuclease inhibitor protein Gam BROMI PF14961.6 CDJ84139.1 - 0.0035 14.8 0.0 0.023 12.2 0.0 1.9 2 0 0 2 2 2 2 Broad-minded protein LBP_BPI_CETP PF01273.25 CDJ84140.1 - 1.7e-14 53.8 0.0 2.3e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain ABC_membrane PF00664.23 CDJ84141.1 - 1.9e-52 178.6 34.6 1.1e-30 107.3 13.0 3.0 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ84141.1 - 6.6e-50 169.2 0.1 1.5e-28 100.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CDJ84141.1 - 2.1e-12 46.9 0.0 0.00094 18.7 0.0 4.0 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CDJ84141.1 - 3e-10 40.4 6.3 0.029 14.2 0.1 4.3 2 2 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CDJ84141.1 - 1e-06 28.4 1.3 0.015 15.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CDJ84141.1 - 1.9e-06 28.0 0.2 0.0062 16.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 CDJ84141.1 - 8.1e-05 23.2 1.6 0.03 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 CDJ84141.1 - 0.00052 20.2 0.0 0.48 10.7 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit T2SSE PF00437.20 CDJ84141.1 - 0.00082 18.5 0.1 0.29 10.2 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Roc PF08477.13 CDJ84141.1 - 0.0011 19.2 0.7 3.9 7.7 0.0 4.6 5 0 0 5 5 5 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CDJ84141.1 - 0.0012 18.8 0.2 1.4 8.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 CDJ84141.1 - 0.0023 18.2 1.7 0.83 9.9 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ84141.1 - 0.0026 18.2 1.0 0.67 10.3 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 CDJ84141.1 - 0.023 14.2 0.5 0.18 11.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 CDJ84141.1 - 0.03 13.6 0.4 1.4 8.1 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 CDJ84141.1 - 0.033 14.1 1.6 2.2 8.2 0.0 2.8 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 CDJ84141.1 - 0.064 13.0 0.7 0.81 9.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CDJ84141.1 - 0.065 13.4 0.0 2.3 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 CDJ84141.1 - 0.072 12.7 0.2 1.6 8.3 0.1 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.23 CDJ84141.1 - 0.086 12.9 2.8 3.3 7.7 0.1 2.4 2 0 0 2 2 2 0 Dynamin family DUF87 PF01935.17 CDJ84141.1 - 0.088 12.9 0.1 0.088 12.9 0.1 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 CDJ84141.1 - 0.09 11.7 1.0 2.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 CDJ84141.1 - 0.097 12.7 2.7 12 5.9 0.2 3.4 4 0 0 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_15 PF13175.6 CDJ84141.1 - 0.1 12.3 0.2 0.2 11.3 0.2 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 CDJ84141.1 - 0.2 12.2 2.9 19 5.8 0.2 3.0 3 1 0 3 3 2 0 AAA domain cobW PF02492.19 CDJ84141.1 - 0.25 10.9 1.1 0.95 9.0 0.4 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.29 CDJ84141.1 - 0.43 10.3 1.5 1.1 9.0 0.3 2.3 2 1 0 2 2 2 0 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.18 CDJ84141.1 - 0.57 9.5 2.8 0.47 9.8 0.1 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.22 CDJ84141.1 - 1.3 8.2 3.7 18 4.4 0.8 2.7 2 1 0 2 2 2 0 NB-ARC domain DUF1712 PF08217.11 CDJ84142.1 - 4.6e-29 101.4 0.6 2.3e-21 76.0 0.6 3.0 2 2 1 3 3 3 2 Fungal domain of unknown function (DUF1712) DUF4372 PF14294.6 CDJ84142.1 - 0.062 13.5 0.1 7 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4372) FGF PF00167.18 CDJ84143.1 - 4.6e-40 136.6 0.1 7.6e-40 135.9 0.1 1.4 1 0 0 1 1 1 1 Fibroblast growth factor DUF1962 PF09227.10 CDJ84143.1 - 0.042 14.2 0.0 0.089 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1962) zf-C2H2_2 PF12756.7 CDJ84144.1 - 0.036 14.4 0.2 0.059 13.7 0.2 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Ribosomal_L28e PF01778.17 CDJ84145.1 - 4.2e-32 111.3 0.5 4.2e-32 111.3 0.5 2.2 3 0 0 3 3 3 1 Ribosomal L28e protein family Mak16 PF04874.14 CDJ84145.1 - 2e-28 98.9 14.7 2e-28 98.9 14.7 2.8 2 1 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 CDJ84145.1 - 2.9e-05 23.6 17.5 3.8e-05 23.2 17.5 1.1 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 CDJ84145.1 - 1.1 7.4 25.7 1.4 7.0 25.7 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleo_P87 PF07267.11 CDJ84145.1 - 6.6 5.5 17.9 0.097 11.5 2.8 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 7TM_GPCR_Srd PF10317.9 CDJ84146.1 - 1.2e-12 47.6 2.2 1.4e-12 47.4 2.2 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd Vma12 PF11712.8 CDJ84146.1 - 0.068 13.2 1.7 0.082 13.0 1.7 1.1 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Ion_trans_2 PF07885.16 CDJ84147.1 - 4.3e-34 116.3 17.5 2.2e-17 62.8 0.1 2.6 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CDJ84147.1 - 0.0014 17.9 12.2 0.4 9.9 0.1 2.3 2 0 0 2 2 2 2 Ion transport protein Unstab_antitox PF09720.10 CDJ84147.1 - 0.023 14.8 0.1 2.5 8.2 0.0 2.7 2 0 0 2 2 2 0 Putative addiction module component FGGY_N PF00370.21 CDJ84147.1 - 0.024 14.2 0.1 0.054 13.0 0.1 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Ctr PF04145.15 CDJ84147.1 - 0.096 13.3 0.2 0.096 13.3 0.2 3.8 3 2 1 4 4 4 0 Ctr copper transporter family DUF2207 PF09972.9 CDJ84147.1 - 6 5.5 8.0 4.1 6.1 4.5 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Gp-FAR-1 PF05823.12 CDJ84148.1 - 1.1e-17 64.8 0.1 1.9e-17 64.0 0.1 1.4 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Rop-like PF05082.13 CDJ84148.1 - 0.0086 15.9 0.2 0.089 12.6 0.1 2.2 2 0 0 2 2 2 1 Rop-like MF_alpha_N PF05436.11 CDJ84148.1 - 0.064 13.2 0.9 0.28 11.1 0.0 2.4 3 0 0 3 3 3 0 Mating factor alpha precursor N-terminus SpoIIM PF01944.17 CDJ84149.1 - 0.0017 18.4 1.3 0.0029 17.6 1.3 1.3 1 0 0 1 1 1 1 Stage II sporulation protein M Baculo_PEP_C PF04513.12 CDJ84149.1 - 0.0047 17.0 0.6 0.0047 17.0 0.6 1.9 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 CDJ84149.1 - 0.036 12.1 6.5 0.052 11.5 5.5 1.6 1 1 1 2 2 2 0 Prominin DUF4131 PF13567.6 CDJ84149.1 - 0.081 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Fib_alpha PF08702.10 CDJ84149.1 - 0.1 12.8 0.9 0.23 11.7 0.9 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2207 PF09972.9 CDJ84149.1 - 0.1 11.3 1.2 0.16 10.7 1.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3810 PF12725.7 CDJ84149.1 - 0.12 11.7 4.4 0.36 10.1 4.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Skp1_POZ PF03931.15 CDJ84149.1 - 0.14 12.4 1.6 0.35 11.1 0.2 2.4 2 1 0 2 2 2 0 Skp1 family, tetramerisation domain YccF PF03733.13 CDJ84149.1 - 3.3 8.5 16.5 3.6 8.4 1.7 2.4 2 0 0 2 2 2 0 Inner membrane component domain DUF1697 PF08002.11 CDJ84150.1 - 0.012 16.1 0.2 0.019 15.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) DUF4200 PF13863.6 CDJ84150.1 - 0.026 14.9 2.6 0.042 14.3 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Prominin PF05478.11 CDJ84150.1 - 0.034 12.1 6.4 0.11 10.5 2.0 2.2 1 1 1 2 2 2 0 Prominin Activator-TraM PF11657.8 CDJ84150.1 - 0.07 13.0 1.0 0.14 12.0 1.0 1.6 1 0 0 1 1 1 0 Transcriptional activator TraM RhodobacterPufX PF11511.8 CDJ84150.1 - 0.11 12.1 2.9 0.27 10.9 2.9 1.6 1 0 0 1 1 1 0 Intrinsic membrane protein PufX MitMem_reg PF13012.6 CDJ84150.1 - 0.11 12.9 0.0 0.44 11.0 0.0 1.8 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function FadA PF09403.10 CDJ84150.1 - 0.48 10.9 3.9 2.2 8.8 3.9 2.0 1 1 0 1 1 1 0 Adhesion protein FadA Myb_DNA-bind_5 PF13873.6 CDJ84151.1 - 3.7e-06 26.9 3.9 0.00052 20.0 0.8 2.5 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain PKcGMP_CC PF16808.5 CDJ84151.1 - 0.0021 17.9 3.8 0.005 16.7 3.8 1.6 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase TpcC PF12642.7 CDJ84151.1 - 0.016 15.0 0.1 0.028 14.2 0.1 1.4 1 0 0 1 1 1 0 Conjugative transposon protein TcpC TMF_DNA_bd PF12329.8 CDJ84151.1 - 0.086 12.8 2.5 0.09 12.8 0.3 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3158 PF11358.8 CDJ84151.1 - 0.091 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3158) Ribosomal_S15 PF00312.22 CDJ84151.1 - 0.093 12.9 0.7 0.48 10.7 0.1 2.6 2 0 0 2 2 2 0 Ribosomal protein S15 CDP-OH_P_transf PF01066.21 CDJ84154.1 - 0.046 14.5 0.2 0.061 14.1 0.2 1.3 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase DUF4400 PF14348.6 CDJ84154.1 - 0.12 11.9 0.1 0.15 11.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) DUF21 PF01595.20 CDJ84155.1 - 2.6e-29 102.2 0.0 3.7e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CDJ84155.1 - 2.4e-07 31.1 1.5 0.0026 18.2 0.3 3.4 3 0 0 3 3 3 2 CBS domain Prefoldin_2 PF01920.20 CDJ84155.1 - 0.018 15.0 4.2 1.7 8.6 0.1 2.4 2 0 0 2 2 2 0 Prefoldin subunit DUF2170 PF09938.9 CDJ84155.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) STELLO PF03385.17 CDJ84156.1 - 3.9e-59 200.4 3.3 4.8e-59 200.1 3.3 1.1 1 0 0 1 1 1 1 STELLO glycosyltransferases Clathrin PF00637.20 CDJ84157.1 - 8.7e-10 38.6 1.7 0.00015 21.7 0.2 4.6 3 1 1 4 4 4 2 Region in Clathrin and VPS TPR_7 PF13176.6 CDJ84157.1 - 9.4e-06 25.3 17.2 1.6 9.0 0.1 7.7 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ84157.1 - 0.00016 21.5 27.8 1 9.7 0.7 7.4 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ84157.1 - 0.0049 17.6 25.4 43 5.3 0.1 9.3 9 2 1 10 10 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ84157.1 - 0.013 15.3 16.8 2.9 7.8 0.1 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ84157.1 - 0.026 14.8 22.7 6.1 7.2 0.1 7.1 5 2 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ84157.1 - 0.029 14.5 14.1 6.8 7.2 0.3 6.6 6 1 1 7 7 6 0 Tetratricopeptide repeat Ribonuc_red_lgC PF02867.15 CDJ84157.1 - 0.036 12.6 0.1 0.064 11.8 0.1 1.3 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain DZR PF12773.7 CDJ84157.1 - 0.042 13.9 9.3 2.4 8.3 10.2 2.6 1 1 1 2 2 2 0 Double zinc ribbon DUF4135 PF13575.6 CDJ84157.1 - 0.089 12.1 0.1 3 7.1 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4135) RPN7 PF10602.9 CDJ84157.1 - 0.13 11.9 3.2 0.73 9.5 0.4 3.6 2 1 1 4 4 4 0 26S proteasome subunit RPN7 ANAPC3 PF12895.7 CDJ84157.1 - 0.33 11.2 13.0 31 4.9 0.2 6.2 6 1 1 7 7 6 0 Anaphase-promoting complex, cyclosome, subunit 3 Stc1 PF12898.7 CDJ84157.1 - 0.46 11.1 1.9 1.3 9.7 1.9 1.7 1 0 0 1 1 1 0 Stc1 domain MIT PF04212.18 CDJ84157.1 - 2.8 8.1 10.9 44 4.2 0.4 4.9 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 CDJ84157.1 - 7.3 7.5 16.0 18 6.3 0.1 6.4 7 1 0 7 7 5 0 Tetratricopeptide repeat BRCT_2 PF16589.5 CDJ84158.1 - 0.15 12.5 0.2 0.33 11.4 0.2 1.7 1 1 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Adeno_E3_CR2 PF02439.15 CDJ84158.1 - 0.19 11.5 0.5 0.37 10.6 0.5 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Coprogen_oxidas PF01218.18 CDJ84158.1 - 0.2 10.3 0.2 0.27 9.9 0.2 1.2 1 0 0 1 1 1 0 Coproporphyrinogen III oxidase WD40_3 PF15911.5 CDJ84159.1 - 2.7e-15 56.1 0.1 1e-14 54.2 0.0 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ84159.1 - 8.5e-07 29.2 0.6 0.55 10.6 0.0 5.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ84159.1 - 0.015 16.2 0.4 44 5.2 0.0 4.8 5 1 0 5 5 5 0 WD domain, G-beta repeat WD40_like PF17005.5 CDJ84159.1 - 0.074 12.4 4.0 3.8 6.8 0.1 2.9 4 1 0 4 4 4 0 WD40-like domain Ribosomal_S13_N PF08069.12 CDJ84160.1 - 3.7e-31 107.0 0.4 8.2e-31 105.8 0.4 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 CDJ84160.1 - 6.1e-13 48.8 0.8 9.8e-13 48.1 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 CDJ84160.1 - 0.0024 17.8 0.1 0.0058 16.5 0.1 1.7 2 1 0 2 2 2 1 'Paired box' domain R3H PF01424.22 CDJ84161.1 - 3.8e-10 39.6 0.0 9e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 CDJ84161.1 - 6.5e-09 35.7 68.0 8.5e-05 22.5 15.5 13.9 15 2 0 15 15 15 7 NF-X1 type zinc finger B56 PF01603.20 CDJ84163.1 - 4.9e-182 605.5 5.2 5.9e-182 605.3 5.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) PH PF00169.29 CDJ84164.1 - 2.2e-10 41.0 0.0 6.7e-10 39.4 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 CDJ84164.1 - 2.5e-08 34.3 0.0 5.3e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain ketoacyl-synt PF00109.26 CDJ84165.1 - 2.4e-63 214.1 0.2 3.9e-63 213.4 0.2 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PP-binding PF00550.25 CDJ84165.1 - 1.8e-54 181.9 3.0 2.3e-12 47.1 0.0 4.5 4 0 0 4 4 4 4 Phosphopantetheine attachment site Ketoacyl-synt_C PF02801.22 CDJ84165.1 - 1.6e-28 99.1 0.0 4.5e-28 97.6 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 CDJ84165.1 - 1.1e-06 29.1 0.0 6.3e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 CDJ84165.1 - 0.00015 21.2 1.2 0.0013 18.1 1.2 2.1 1 1 0 1 1 1 1 Thiolase, N-terminal domain CNP_C_terminal PF17839.1 CDJ84165.1 - 0.0072 17.1 0.1 8.3 7.2 0.0 3.4 3 0 0 3 3 3 1 C-terminal domain of cyclic nucleotide phosphodiesterase GST_C PF00043.25 CDJ84165.1 - 0.011 15.9 0.0 15 5.9 0.0 3.5 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain FAE1_CUT1_RppA PF08392.12 CDJ84165.1 - 0.079 12.3 0.3 0.15 11.3 0.3 1.3 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein Laminin_EGF PF00053.24 CDJ84166.1 - 2.6e-46 155.5 348.0 0.00077 19.6 13.3 18.3 2 2 15 17 17 17 15 Laminin EGF domain hEGF PF12661.7 CDJ84166.1 - 0.00014 22.4 32.7 0.0007 20.1 3.4 23.7 22 4 4 26 26 26 13 Human growth factor-like EGF EGF_2 PF07974.13 CDJ84166.1 - 0.0032 17.8 14.5 0.0032 17.8 14.5 30.6 25 10 4 29 29 29 15 EGF-like domain zf-RRN7 PF11781.8 CDJ84167.1 - 0.00051 19.7 0.6 0.00051 19.7 0.6 2.1 2 0 0 2 2 2 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 OrfB_Zn_ribbon PF07282.11 CDJ84167.1 - 0.0084 16.0 1.2 0.0084 16.0 1.2 2.1 2 0 0 2 2 2 1 Putative transposase DNA-binding domain FlaF PF07309.11 CDJ84167.1 - 0.14 12.2 0.6 0.32 11.0 0.6 1.5 1 0 0 1 1 1 0 Flagellar protein FlaF TF_Zn_Ribbon PF08271.12 CDJ84167.1 - 0.36 10.4 1.3 0.82 9.2 1.3 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Auto_anti-p27 PF06677.12 CDJ84167.1 - 0.51 10.5 3.2 2.6 8.3 1.5 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-RRPl_C4 PF17026.5 CDJ84167.1 - 2 8.5 6.3 0.74 9.9 0.1 3.1 4 0 0 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type CBM_20 PF00686.19 CDJ84168.1 - 1.9e-07 30.9 0.0 2.3e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Starch binding domain RRM_1 PF00076.22 CDJ84169.1 - 1.5e-17 63.1 0.0 2.7e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ84169.1 - 0.00048 20.2 0.0 0.00095 19.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 CDJ84169.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Aa_trans PF01490.18 CDJ84170.1 - 5.3e-69 232.9 31.6 6.6e-69 232.6 31.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Mito_carr PF00153.27 CDJ84171.1 - 1.9e-63 210.4 0.9 3.8e-21 74.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ERK-JNK_inhib PF15002.6 CDJ84172.1 - 2.7e-48 164.3 7.8 3.4e-48 163.9 7.8 1.1 1 0 0 1 1 1 1 ERK and JNK pathways, inhibitor LRR_8 PF13855.6 CDJ84173.1 - 1.5e-15 56.7 6.2 2e-09 37.1 7.1 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CDJ84173.1 - 2.8e-11 43.5 11.9 2.8e-05 24.4 3.5 3.0 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDJ84173.1 - 0.00055 20.1 11.0 0.65 10.8 1.1 4.9 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 CDJ84173.1 - 0.016 15.2 2.0 9.6 6.6 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich repeat DUF4776 PF16003.5 CDJ84173.1 - 0.21 10.6 9.9 0.28 10.1 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) GATase_5 PF13507.6 CDJ84174.1 - 1.9e-98 328.7 0.0 2.4e-98 328.4 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 CDJ84174.1 - 5e-11 43.0 0.0 8.9e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain Helicase_C PF00271.31 CDJ84175.1 - 1.3e-14 54.5 0.1 2.6e-12 47.1 0.1 3.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ84175.1 - 3.3e-12 46.5 0.0 5.8e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ84175.1 - 9.3e-06 25.7 0.0 1.6e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Homeodomain PF00046.29 CDJ84176.1 - 2.4e-23 81.7 2.8 3.9e-23 81.1 2.8 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ84176.1 - 0.0082 16.0 0.1 0.019 14.9 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain RhoGEF67_u1 PF16615.5 CDJ84176.1 - 0.071 13.6 0.3 0.071 13.6 0.3 2.6 2 1 1 3 3 2 0 Unstructured region one on RhoGEF 6 and 7 DNA_pol_A PF00476.20 CDJ84177.1 - 3e-91 306.3 0.0 5.3e-91 305.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_B PF00136.21 CDJ84177.1 - 5.1e-91 305.7 0.0 1.5e-90 304.1 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CDJ84177.1 - 2.9e-19 69.4 0.0 1.7e-13 50.5 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain HTH_psq PF05225.16 CDJ84177.1 - 0.0082 15.9 0.2 0.43 10.4 0.0 3.0 3 0 0 3 3 3 1 helix-turn-helix, Psq domain COesterase PF00135.28 CDJ84178.1 - 7.1e-115 384.8 0.2 1.9e-114 383.3 0.2 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDJ84178.1 - 3.9e-12 46.5 0.1 1.6e-11 44.5 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CDJ84178.1 - 0.0047 16.4 0.1 0.01 15.4 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 CDJ84178.1 - 0.18 10.7 0.1 0.85 8.4 0.1 1.9 1 1 0 1 1 1 0 Steryl acetyl hydrolase Esterase_phd PF10503.9 CDJ84178.1 - 0.18 11.3 0.0 0.5 9.8 0.0 1.7 1 1 0 1 1 1 0 Esterase PHB depolymerase DUF5326 PF17260.2 CDJ84178.1 - 2.5 8.3 7.6 6.1 7.1 7.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5326) FixQ PF05545.11 CDJ84178.1 - 4.9 7.2 6.0 16 5.6 6.0 1.9 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ zf-C4 PF00105.18 CDJ84179.1 - 5.3e-27 94.1 17.3 5.3e-27 94.1 17.3 1.7 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ84179.1 - 0.047 13.3 0.3 0.15 11.6 0.3 1.8 1 1 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor UDPGP PF01704.18 CDJ84180.1 - 1.4e-10 40.4 0.0 1.8e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 CDJ84180.1 - 0.0038 17.6 0.4 0.0089 16.4 0.4 1.9 1 1 0 1 1 1 1 MobA-like NTP transferase domain T4_baseplate PF12322.8 CDJ84180.1 - 0.039 13.4 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 T4 bacteriophage base plate protein OmdA PF13376.6 CDJ84180.1 - 0.36 10.9 1.4 21 5.2 0.0 2.6 2 1 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Prefoldin_2 PF01920.20 CDJ84181.1 - 3.3e-12 46.3 5.1 4.3e-12 45.9 5.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit KIP1 PF07765.12 CDJ84181.1 - 0.046 13.8 1.0 9.3 6.5 0.1 2.4 2 1 0 2 2 2 0 KIP1-like protein Mito_carr PF00153.27 CDJ84182.1 - 1.3e-47 159.6 7.5 3e-17 62.3 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Gpi1 PF05024.15 CDJ84183.1 - 9.6e-22 78.0 4.2 1.2e-21 77.7 4.2 1.1 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) ABC_tran PF00005.27 CDJ84184.1 - 1.2e-20 74.4 0.0 1.6e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CDJ84184.1 - 0.00024 21.0 0.2 0.22 11.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CDJ84184.1 - 0.0003 21.2 0.1 0.00042 20.7 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 CDJ84184.1 - 0.00088 18.9 0.1 0.0015 18.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CDJ84184.1 - 0.00095 19.1 0.2 0.0017 18.2 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 CDJ84184.1 - 0.0019 18.4 0.0 0.0031 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 CDJ84184.1 - 0.0097 15.5 0.3 0.022 14.4 0.2 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CDJ84184.1 - 0.019 15.1 0.1 0.038 14.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 CDJ84184.1 - 0.033 13.5 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_29 PF13555.6 CDJ84184.1 - 0.045 13.5 0.1 0.091 12.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 CDJ84184.1 - 0.047 13.0 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 CDJ84184.1 - 0.047 13.8 0.2 0.083 13.0 0.2 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 CDJ84184.1 - 0.063 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 CDJ84184.1 - 0.069 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 CDJ84184.1 - 0.069 13.4 0.2 0.17 12.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CDJ84184.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CDJ84184.1 - 0.14 12.2 0.2 0.24 11.4 0.2 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE 7tm_1 PF00001.21 CDJ84185.1 - 3.1e-38 131.6 0.1 4.3e-38 131.1 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ84185.1 - 0.00013 21.4 1.3 0.029 13.7 0.0 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 CDJ84185.1 - 0.031 13.6 1.3 0.11 11.7 0.0 2.2 2 1 1 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srw FAM60A PF15396.6 CDJ84185.1 - 0.057 13.4 2.2 0.078 13.0 2.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF3693 PF12472.8 CDJ84185.1 - 0.17 11.5 1.5 0.36 10.5 1.5 1.5 1 0 0 1 1 1 0 Phage related protein Ctr PF04145.15 CDJ84185.1 - 0.31 11.6 4.0 1.4 9.5 3.8 2.1 1 1 0 1 1 1 0 Ctr copper transporter family FA_desaturase PF00487.24 CDJ84185.1 - 0.47 10.2 1.8 0.75 9.6 0.0 2.0 2 1 0 2 2 2 0 Fatty acid desaturase Guanylate_kin PF00625.21 CDJ84186.1 - 3.3e-35 121.4 0.0 7.3e-33 113.8 0.0 2.4 1 1 0 1 1 1 1 Guanylate kinase PDZ PF00595.24 CDJ84186.1 - 1.9e-11 44.2 0.1 4.1e-11 43.1 0.1 1.6 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDJ84186.1 - 1.1e-08 34.8 0.3 3.9e-08 33.0 0.2 2.0 2 0 0 2 2 2 1 PDZ domain SH3_1 PF00018.28 CDJ84186.1 - 2.3e-06 27.1 1.4 9.3e-06 25.2 0.7 2.4 2 1 0 2 2 2 1 SH3 domain AAA_5 PF07728.14 CDJ84186.1 - 0.00064 19.7 0.0 0.0027 17.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) SH3_9 PF14604.6 CDJ84186.1 - 0.0063 16.4 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PDZ_2 PF13180.6 CDJ84186.1 - 0.0091 16.3 0.1 0.021 15.1 0.1 1.5 1 0 0 1 1 1 1 PDZ domain ApoLp-III PF07464.11 CDJ84186.1 - 0.019 15.1 0.1 0.033 14.3 0.1 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) AAA_22 PF13401.6 CDJ84186.1 - 0.13 12.5 0.0 0.98 9.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain CooT PF10133.9 CDJ84186.1 - 0.18 12.1 0.4 0.97 9.8 0.0 2.2 2 0 0 2 2 2 0 CO dehydrogenase accessory protein CooT NEMP PF10225.9 CDJ84187.1 - 4.8e-60 203.3 7.5 1e-59 202.2 7.5 1.5 1 0 0 1 1 1 1 NEMP family Syndecan PF01034.20 CDJ84187.1 - 0.41 10.6 1.5 1.1 9.2 1.1 2.0 1 1 0 1 1 1 0 Syndecan domain GDPD PF03009.17 CDJ84188.1 - 1.1e-42 146.5 0.0 1.6e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Gp-FAR-1 PF05823.12 CDJ84189.1 - 2.8e-38 131.6 7.4 3.2e-38 131.4 7.4 1.0 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ApoLp-III PF07464.11 CDJ84189.1 - 6.4e-05 23.1 2.6 0.00019 21.5 1.0 2.2 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) DUF3106 PF11304.8 CDJ84189.1 - 0.0014 19.1 3.5 0.45 11.0 0.2 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3106) DUF848 PF05852.11 CDJ84189.1 - 0.022 14.9 2.0 0.41 10.7 0.2 2.2 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Syntaxin_2 PF14523.6 CDJ84189.1 - 0.037 14.4 0.4 0.072 13.5 0.4 1.6 1 1 0 1 1 1 0 Syntaxin-like protein Syntaxin PF00804.25 CDJ84189.1 - 0.039 13.6 2.8 0.056 13.1 2.8 1.2 1 0 0 1 1 1 0 Syntaxin Methyltransf_9 PF08003.11 CDJ84189.1 - 0.049 12.5 0.7 0.92 8.4 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1698) kleA_kleC PF17383.2 CDJ84189.1 - 0.17 12.2 3.0 0.23 11.8 0.9 2.1 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A YtxH PF12732.7 CDJ84189.1 - 4.5 7.9 7.8 9.2 6.9 4.6 2.9 2 1 0 2 2 2 0 YtxH-like protein Gp-FAR-1 PF05823.12 CDJ84190.1 - 2.6e-36 125.2 5.7 3e-36 125.0 5.7 1.0 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF3106 PF11304.8 CDJ84190.1 - 8.4e-06 26.2 0.2 0.00011 22.6 0.2 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF3106) ApoLp-III PF07464.11 CDJ84190.1 - 0.00015 21.9 1.6 0.074 13.1 0.6 2.5 2 1 0 2 2 2 2 Apolipophorin-III precursor (apoLp-III) TipAS PF07739.13 CDJ84190.1 - 0.0015 19.0 2.9 0.0028 18.2 2.9 1.6 1 1 0 1 1 1 1 TipAS antibiotic-recognition domain DUF4473 PF14747.6 CDJ84190.1 - 0.014 15.9 3.6 0.69 10.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) BMFP PF04380.13 CDJ84190.1 - 0.014 15.8 1.2 2.3 8.8 0.1 3.0 3 0 0 3 3 3 0 Membrane fusogenic activity DctP PF03480.13 CDJ84190.1 - 0.018 14.4 0.8 3.7 6.8 0.0 2.6 2 2 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 Ferritin-like PF12902.7 CDJ84190.1 - 0.023 14.6 0.2 0.028 14.3 0.2 1.1 1 0 0 1 1 1 0 Ferritin-like EF-G-binding_N PF07299.11 CDJ84190.1 - 0.044 14.3 0.5 0.52 10.9 0.1 2.5 3 0 0 3 3 3 0 Elongation factor G-binding protein, N-terminal DUF948 PF06103.11 CDJ84190.1 - 0.06 13.6 0.1 1.9 8.8 0.0 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Metal_resist PF13801.6 CDJ84190.1 - 0.086 13.0 0.0 20 5.4 0.2 2.5 1 1 1 3 3 3 0 Heavy-metal resistance LTXXQ PF07813.12 CDJ84190.1 - 0.095 13.4 1.9 13 6.6 0.0 2.8 2 1 1 3 3 3 0 LTXXQ motif family protein ZYG-11_interact PF05884.12 CDJ84190.1 - 0.15 11.4 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 SieB PF14163.6 CDJ84190.1 - 0.16 11.5 0.0 4.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Super-infection exclusion protein B NepR PF18557.1 CDJ84190.1 - 0.96 9.1 0.0 0.96 9.1 0.0 2.7 3 0 0 3 3 3 0 Anti-sigma factor NepR 7tm_1 PF00001.21 CDJ84191.1 - 2.7e-73 246.6 6.9 3.6e-73 246.2 6.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ84191.1 - 5.1e-13 49.0 14.0 3.7e-08 33.1 9.2 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 CDJ84191.1 - 4.4e-06 26.6 12.3 4.4e-05 23.4 7.8 2.4 2 1 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srx PF10328.9 CDJ84191.1 - 7.1e-06 25.8 7.0 7.1e-06 25.8 7.0 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF1218 PF06749.12 CDJ84191.1 - 2.2 8.9 8.9 9.8 6.8 1.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1218) DUF2207 PF09972.9 CDJ84191.1 - 4.7 5.9 6.6 2.3 6.9 0.1 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Cg6151-P PF10233.9 CDJ84192.1 - 1.3 9.3 2.4 71 3.8 0.1 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein CG6151-P Frag1 PF10277.9 CDJ84193.1 - 4.1e-26 91.9 17.9 3.4e-23 82.3 14.2 2.1 2 0 0 2 2 2 2 Frag1/DRAM/Sfk1 family CitMHS PF03600.16 CDJ84193.1 - 0.008 15.4 0.2 0.014 14.7 0.2 1.5 1 1 0 1 1 1 1 Citrate transporter PalH PF08733.10 CDJ84193.1 - 1.7 7.6 8.3 0.44 9.5 4.8 1.6 1 1 0 1 1 1 0 PalH/RIM21 Presenilin PF01080.17 CDJ84193.1 - 6.7 5.4 7.8 9 4.9 7.8 1.1 1 0 0 1 1 1 0 Presenilin Ldl_recept_a PF00057.18 CDJ84194.1 - 2.8e-18 65.8 39.9 5.1e-08 33.0 10.4 4.2 3 1 1 4 4 4 3 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 CDJ84194.1 - 4.9e-18 65.3 9.9 0.0017 18.8 0.1 9.5 9 0 0 9 9 9 5 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 CDJ84194.1 - 9.6e-14 51.4 60.7 7.6e-10 38.9 5.9 5.8 5 0 0 5 5 5 4 Coagulation Factor Xa inhibitory site DUF5050 PF16472.5 CDJ84194.1 - 0.00036 19.9 0.5 0.0089 15.3 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF5050) Plasmod_Pvs28 PF06247.11 CDJ84194.1 - 0.53 10.6 5.9 3.9 7.9 0.7 3.1 2 0 0 2 2 2 0 Pvs28 EGF domain cEGF PF12662.7 CDJ84194.1 - 0.91 9.5 23.1 0.2 11.6 0.2 4.7 4 0 0 4 4 4 0 Complement Clr-like EGF-like F-box-like PF12937.7 CDJ84195.1 - 1.1e-07 31.6 0.1 3.4e-07 30.1 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDJ84195.1 - 4.9e-07 29.5 0.3 1.1e-06 28.3 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 CDJ84195.1 - 0.014 15.3 0.0 0.1 12.5 0.0 2.2 2 0 0 2 2 2 0 F-box Acyl_transf_1 PF00698.21 CDJ84196.1 - 1.7e-72 244.7 0.0 2.6e-72 244.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 CDJ84196.1 - 1.7e-72 244.0 0.0 3.1e-72 243.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 CDJ84196.1 - 2.3e-46 157.9 0.3 8.6e-45 152.8 0.0 2.9 3 0 0 3 3 3 1 KR domain Ketoacyl-synt_C PF02801.22 CDJ84196.1 - 6e-41 139.2 0.0 1.2e-40 138.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 CDJ84196.1 - 3.7e-30 104.7 0.0 7.9e-30 103.6 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thioesterase PF00975.20 CDJ84196.1 - 4.7e-19 69.4 0.0 1.4e-18 67.9 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain ADH_zinc_N PF00107.26 CDJ84196.1 - 2.8e-18 66.1 0.0 9.7e-18 64.4 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDJ84196.1 - 1.1e-15 58.9 0.1 4.8e-14 53.5 0.0 3.0 3 0 0 3 3 2 1 Zinc-binding dehydrogenase PS-DH PF14765.6 CDJ84196.1 - 5.9e-15 55.3 0.0 2.3e-14 53.4 0.0 1.7 1 1 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.25 CDJ84196.1 - 9.5e-10 38.2 0.0 2.3e-06 27.2 0.0 2.8 2 0 0 2 2 2 2 short chain dehydrogenase PP-binding PF00550.25 CDJ84196.1 - 1.1e-09 38.5 1.9 3.1e-09 37.0 0.4 2.6 3 0 0 3 3 2 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 CDJ84196.1 - 0.00087 19.2 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 CDJ84196.1 - 0.0041 16.5 0.0 0.009 15.4 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_1 PF00561.20 CDJ84196.1 - 0.016 14.9 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold ACP_syn_III PF08545.10 CDJ84196.1 - 0.034 14.0 0.6 0.14 12.0 0.5 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III YjeF_N PF03853.15 CDJ84196.1 - 0.035 14.0 0.1 0.36 10.7 0.0 2.6 2 0 0 2 2 2 0 YjeF-related protein N-terminus AlaDh_PNT_C PF01262.21 CDJ84196.1 - 0.057 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Astacin PF01400.24 CDJ84197.1 - 6.2e-63 211.9 0.0 1.5e-62 210.6 0.0 1.7 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) CUB PF00431.20 CDJ84197.1 - 6.8e-15 55.4 0.0 1.3e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 CUB domain Peptidase_M10 PF00413.24 CDJ84197.1 - 0.002 18.0 0.2 0.091 12.6 0.0 2.2 2 0 0 2 2 2 1 Matrixin Reprolysin_4 PF13583.6 CDJ84197.1 - 0.0073 16.0 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 CDJ84197.1 - 0.012 14.6 0.1 0.019 13.9 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 zf-C2H2_4 PF13894.6 CDJ84198.1 - 0.59 11.1 3.6 9.9 7.3 1.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger HGTP_anticodon2 PF12745.7 CDJ84199.1 - 0.013 15.1 2.1 0.014 14.9 2.1 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Mem_trans PF03547.18 CDJ84199.1 - 0.11 10.9 0.0 0.12 10.7 0.0 1.0 1 0 0 1 1 1 0 Membrane transport protein IF-2B PF01008.17 CDJ84200.1 - 3.1e-55 187.4 0.9 6e-37 127.4 0.0 2.0 2 0 0 2 2 2 2 Initiation factor 2 subunit family 7TM_GPCR_Srd PF10317.9 CDJ84201.1 - 2.3e-30 105.8 0.2 2.7e-30 105.6 0.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Str PF10326.9 CDJ84201.1 - 1.4e-07 31.2 0.6 1.6e-07 31.0 0.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srj PF10319.9 CDJ84201.1 - 6.2e-07 29.1 0.2 7.5e-07 28.8 0.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Srh PF10318.9 CDJ84201.1 - 1.6e-06 27.4 0.6 2.1e-06 27.0 0.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Srd PF10317.9 CDJ84202.1 - 1.4e-45 155.7 18.5 1.1e-23 83.9 6.6 2.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Str PF10326.9 CDJ84202.1 - 0.00013 21.5 11.9 0.046 13.1 0.1 2.6 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srj PF10319.9 CDJ84202.1 - 0.0032 16.9 7.9 0.05 13.0 0.3 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srj Collagen PF01391.18 CDJ84203.1 - 1.6e-18 66.2 72.8 2.2e-08 33.7 28.5 3.6 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ84203.1 - 2.1e-05 24.5 0.4 3.1e-05 24.0 0.4 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Annexin PF00191.20 CDJ84204.1 - 4.6e-43 145.1 11.1 7.9e-17 61.1 0.4 4.2 4 0 0 4 4 4 3 Annexin MGDG_synth PF06925.11 CDJ84204.1 - 0.097 12.8 0.4 2.8 8.0 0.1 2.8 2 1 1 3 3 3 0 Monogalactosyldiacylglycerol (MGDG) synthase 4HBT_3 PF13622.6 CDJ84205.1 - 5e-53 180.9 0.0 6.7e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 CDJ84205.1 - 2e-31 108.6 0.0 2.6e-23 82.3 0.0 3.0 2 1 0 2 2 2 2 Acyl-CoA thioesterase tRNA-synt_2d PF01409.20 CDJ84207.1 - 6.1e-50 170.0 3.4 4.8e-30 104.8 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 CDJ84207.1 - 3.1e-19 69.2 0.2 7.1e-19 68.0 0.2 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Recep_L_domain PF01030.24 CDJ84208.1 - 1.9e-15 57.0 1.5 0.00031 20.9 0.1 4.3 3 1 1 4 4 4 3 Receptor L domain DUF4834 PF16118.5 CDJ84208.1 - 0.006 17.5 4.3 0.011 16.7 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) Rax2 PF12768.7 CDJ84208.1 - 0.018 14.5 0.0 0.051 13.0 0.0 1.8 2 0 0 2 2 2 0 Cortical protein marker for cell polarity DUF2207 PF09972.9 CDJ84208.1 - 0.025 13.3 0.2 0.04 12.7 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Myc_target_1 PF15179.6 CDJ84208.1 - 0.037 13.9 0.1 0.037 13.9 0.1 1.7 2 0 0 2 2 2 0 Myc target protein 1 Stevor PF17410.2 CDJ84208.1 - 0.078 12.5 0.6 0.25 10.8 0.0 1.9 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame EphA2_TM PF14575.6 CDJ84208.1 - 0.11 13.4 0.1 0.41 11.6 0.1 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 CDJ84208.1 - 0.31 10.9 7.2 0.78 9.6 6.5 1.9 1 1 1 2 2 2 0 TMEM154 protein family RIFIN PF02009.16 CDJ84208.1 - 0.57 10.0 4.0 1.4 8.8 3.8 1.7 1 1 0 1 1 1 0 Rifin Shisa PF13908.6 CDJ84208.1 - 0.85 9.8 3.4 3.2 8.0 3.4 1.9 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Tmemb_9 PF05434.11 CDJ84208.1 - 3.8 7.4 5.7 0.55 10.1 0.2 2.3 3 0 0 3 3 3 0 TMEM9 Cation_ATPase_N PF00690.26 CDJ84209.1 - 3.3e-15 55.5 0.0 4.3e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Mo-co_dimer PF03404.16 CDJ84210.1 - 1.2e-42 145.2 0.3 1.9e-42 144.5 0.3 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 CDJ84210.1 - 0.0011 18.7 0.1 0.002 17.8 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Big_7 PF17957.1 CDJ84210.1 - 0.031 15.0 0.1 0.24 12.2 0.1 2.1 1 1 0 1 1 1 0 Bacterial Ig domain BNR PF02012.20 CDJ84210.1 - 0.046 13.7 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 BNR/Asp-box repeat DUF3328 PF11807.8 CDJ84210.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) MARVEL PF01284.23 CDJ84211.1 - 6.6e-11 42.4 28.0 8.4e-11 42.1 28.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain B3 PF02362.21 CDJ84211.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 B3 DNA binding domain DUF3724 PF12521.8 CDJ84211.1 - 0.15 12.0 2.2 10 6.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3724) MRP-S23 PF10484.9 CDJ84212.1 - 7.8e-39 132.9 0.3 8.6e-39 132.7 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S23 MRP-S25 PF13741.6 CDJ84212.1 - 0.0027 17.3 1.2 0.32 10.5 0.0 2.3 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 tRNA-synt_2c PF01411.19 CDJ84213.1 - 3.1e-188 626.8 1.3 9.2e-100 334.7 0.0 3.1 2 1 1 3 3 3 2 tRNA synthetases class II (A) DHHA1 PF02272.19 CDJ84213.1 - 3.8e-18 66.2 5.8 3.8e-18 66.2 5.8 2.4 3 0 0 3 3 3 1 DHHA1 domain tRNA_SAD PF07973.14 CDJ84213.1 - 1e-15 57.5 0.7 2.2e-15 56.5 0.7 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain PTSIIA_gutA PF03829.13 CDJ84213.1 - 0.071 13.0 0.1 1.7 8.6 0.0 2.8 2 1 1 3 3 3 0 PTS system glucitol/sorbitol-specific IIA component ShK PF01549.24 CDJ84214.1 - 1.2e-09 38.5 37.4 1.9e-05 25.1 6.4 4.4 4 0 0 4 4 4 3 ShK domain-like CAP PF00188.26 CDJ84215.1 - 6.7e-11 43.1 0.0 0.0008 20.2 0.2 3.4 2 2 1 3 3 3 2 Cysteine-rich secretory protein family CAP PF00188.26 CDJ84216.1 - 2.5e-05 25.1 0.0 2.5e-05 25.1 0.0 3.3 3 3 0 3 3 3 1 Cysteine-rich secretory protein family TTR-52 PF01060.23 CDJ84217.1 - 3.4e-26 91.7 0.0 4.8e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Transthyretin-like family CAP PF00188.26 CDJ84218.1 - 4.6e-17 63.0 5.3 6.4e-17 62.6 5.3 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ84218.1 - 0.00091 19.5 5.7 0.022 15.0 5.7 2.5 1 1 0 1 1 1 1 Ancylostoma-associated secreted protein related TTR-52 PF01060.23 CDJ84219.1 - 6.9e-30 103.6 0.0 8.4e-30 103.3 0.0 1.1 1 0 0 1 1 1 1 Transthyretin-like family bMG3 PF11974.8 CDJ84219.1 - 0.016 15.2 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain Transthyretin PF00576.21 CDJ84219.1 - 0.11 13.2 0.0 0.14 12.8 0.0 1.2 1 0 0 1 1 1 0 HIUase/Transthyretin family TTR-52 PF01060.23 CDJ84220.1 - 5.2e-29 100.8 0.0 8.7e-29 100.1 0.0 1.4 1 0 0 1 1 1 1 Transthyretin-like family TTR-52 PF01060.23 CDJ84221.1 - 5.3e-29 100.7 0.0 6.6e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 Transthyretin-like family TTR-52 PF01060.23 CDJ84222.1 - 2.4e-27 95.4 0.0 3e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Transthyretin-like family bMG3 PF11974.8 CDJ84222.1 - 0.013 15.5 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain TTR-52 PF01060.23 CDJ84223.1 - 2.7e-27 95.3 0.0 5.2e-27 94.4 0.0 1.5 2 0 0 2 2 2 1 Transthyretin-like family bMG3 PF11974.8 CDJ84223.1 - 0.022 14.8 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain TTR-52 PF01060.23 CDJ84224.1 - 1.5e-27 96.1 0.0 1.9e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Transthyretin-like family bMG3 PF11974.8 CDJ84224.1 - 0.077 13.0 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain TTR-52 PF01060.23 CDJ84225.1 - 5.8e-27 94.2 0.0 7.6e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 Transthyretin-like family Transposase_24 PF03004.14 CDJ84225.1 - 0.14 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) P53 PF00870.18 CDJ84226.1 - 1.6e-49 168.3 0.6 2e-49 168.0 0.6 1.1 1 0 0 1 1 1 1 P53 DNA-binding domain PUA PF01472.20 CDJ84226.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 PUA domain DUF929 PF06053.11 CDJ84227.1 - 0.059 12.7 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF929) SLC35F PF06027.12 CDJ84228.1 - 1.1e-107 360.0 23.5 1.3e-107 359.8 23.5 1.0 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 CDJ84228.1 - 4.2e-11 43.2 26.5 5.7e-07 29.8 12.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 CDJ84228.1 - 9.2e-08 31.4 12.9 1.8e-07 30.4 8.0 2.1 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 CDJ84228.1 - 7.4e-07 28.7 20.8 1.1e-06 28.1 20.7 1.3 1 1 0 1 1 1 1 UAA transporter family RBFA PF02033.18 CDJ84229.1 - 3.8e-05 24.1 0.0 4.5e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Ribosome-binding factor A Chromo_shadow PF01393.19 CDJ84231.1 - 8.7e-07 28.9 0.0 1.5e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Chromo shadow domain GAS PF13851.6 CDJ84232.1 - 5.7e-05 22.6 12.3 5.7e-05 22.6 12.3 8.2 2 2 5 8 8 8 5 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.6 CDJ84232.1 - 0.0061 16.6 4.5 0.0061 16.6 4.5 12.3 9 4 1 11 11 11 2 Centrosome localisation domain of PPC89 WD40 PF00400.32 CDJ84233.1 - 1.3e-30 104.9 20.0 8.7e-09 35.9 0.5 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ84233.1 - 3.6e-06 27.2 0.8 3 8.2 0.0 4.3 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDJ84233.1 - 6.2e-05 21.8 3.2 0.22 10.1 0.0 3.2 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CDJ84233.1 - 0.0041 15.9 0.4 2.6 6.7 0.3 2.5 2 1 0 2 2 2 2 Nup133 N terminal like WD40_like PF17005.5 CDJ84233.1 - 0.087 12.1 0.0 0.32 10.3 0.0 1.9 2 0 0 2 2 2 0 WD40-like domain Frtz PF11768.8 CDJ84233.1 - 0.2 9.9 0.0 5.1 5.3 0.0 2.0 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PID PF00640.23 CDJ84234.1 - 1.1e-25 90.3 0.6 1.6e-25 89.7 0.6 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 CDJ84234.1 - 2.4e-09 37.5 0.4 4.2e-09 36.6 0.4 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.6 CDJ84234.1 - 0.00013 21.9 0.1 0.00018 21.4 0.1 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) DNA_ligase_IV PF11411.8 CDJ84234.1 - 0.18 11.9 11.9 0.66 10.1 1.7 2.8 3 0 0 3 3 3 0 DNA ligase IV Gemini_C4 PF01492.17 CDJ84234.1 - 1.2 9.1 5.7 11 6.1 0.2 2.4 2 0 0 2 2 2 0 Geminivirus C4 protein Peptidase_M16 PF00675.20 CDJ84236.1 - 4.3e-44 150.1 0.7 4.3e-44 150.1 0.7 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CDJ84236.1 - 1.4e-24 87.2 0.0 3.8e-20 72.7 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain Pox_EPC_I2-L1 PF12575.8 CDJ84236.1 - 0.021 15.0 0.2 3.6 7.9 0.0 2.9 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 Dpoe2NT PF12213.8 CDJ84236.1 - 0.11 12.8 0.1 0.3 11.4 0.1 1.7 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal HA2 PF04408.23 CDJ84237.1 - 1.4e-24 86.5 0.2 1.4e-24 86.5 0.2 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDJ84237.1 - 2.5e-21 75.8 0.0 6.5e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDJ84237.1 - 2.9e-12 46.9 0.0 6.7e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ84237.1 - 1.2e-05 25.1 0.1 3.8e-05 23.5 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CDJ84237.1 - 2.6e-05 24.6 0.1 5.2e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDJ84237.1 - 0.00044 20.5 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ84237.1 - 0.005 16.6 0.0 0.0086 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CDJ84237.1 - 0.0074 15.9 0.1 0.014 15.0 0.1 1.5 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.15 CDJ84237.1 - 0.023 14.7 0.0 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 CDJ84237.1 - 0.04 13.4 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 CDJ84237.1 - 0.088 12.2 0.0 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 CDJ84237.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RSB_motif PF16294.5 CDJ84237.1 - 5.9 7.2 15.0 12 6.2 15.0 1.5 1 0 0 1 1 1 0 RNSP1-SAP18 binding (RSB) motif DUF1645 PF07816.11 CDJ84237.1 - 6.9 7.2 18.2 3.4 8.2 14.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) BTB_2 PF02214.22 CDJ84238.1 - 5e-20 71.7 0.0 1.3e-19 70.3 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 CDJ84238.1 - 0.0018 18.5 0.0 0.011 16.0 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 CDJ84238.1 - 0.02 15.0 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Mur_ligase_C PF02875.21 CDJ84238.1 - 0.08 13.2 0.0 23 5.3 0.0 2.8 3 0 0 3 3 3 0 Mur ligase family, glutamate ligase domain Brix PF04427.18 CDJ84239.1 - 4.7e-34 118.2 1.8 7.3e-34 117.6 1.8 1.3 1 0 0 1 1 1 1 Brix domain GCN5L1 PF06320.13 CDJ84239.1 - 0.047 13.8 1.6 0.12 12.5 1.6 1.7 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Snf7 PF03357.21 CDJ84239.1 - 0.15 11.6 7.8 2.4 7.7 0.6 3.3 2 2 1 3 3 3 0 Snf7 DnaJ PF00226.31 CDJ84240.1 - 4.9e-28 97.0 2.3 4.9e-28 97.0 2.3 2.4 2 0 0 2 2 2 1 DnaJ domain CdvA PF18822.1 CDJ84240.1 - 0.00091 19.1 4.9 0.0018 18.1 4.9 1.6 1 0 0 1 1 1 1 CdvA-like coiled-coil domain She9_MDM33 PF05546.11 CDJ84240.1 - 0.031 14.1 0.9 0.052 13.3 0.9 1.3 1 0 0 1 1 1 0 She9 / Mdm33 family eIF3_N PF09440.10 CDJ84240.1 - 0.041 14.3 1.8 0.085 13.3 1.8 1.5 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain COG2 PF06148.11 CDJ84240.1 - 0.064 13.4 1.6 0.12 12.5 1.6 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PP31 PF05311.11 CDJ84240.1 - 0.12 11.9 6.3 0.18 11.3 5.4 1.7 1 1 1 2 2 2 0 Baculovirus 33KDa late protein (PP31) IMS_HHH PF11798.8 CDJ84240.1 - 0.15 12.4 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif KELK PF15796.5 CDJ84240.1 - 0.28 11.6 11.6 0.1 13.1 8.4 1.9 2 0 0 2 2 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase H-kinase_dim PF02895.14 CDJ84240.1 - 0.29 11.6 1.2 0.6 10.5 1.2 1.5 1 0 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain Atg14 PF10186.9 CDJ84240.1 - 1.3 8.1 4.8 2.3 7.2 4.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GrpE PF01025.19 CDJ84240.1 - 2.4 7.8 9.3 4.6 6.9 9.3 1.4 1 0 0 1 1 1 0 GrpE ZapB PF06005.12 CDJ84240.1 - 3.3 8.2 8.7 34 5.0 0.0 2.4 2 0 0 2 2 2 0 Cell division protein ZapB DUF4337 PF14235.6 CDJ84240.1 - 4.2 7.5 13.2 0.63 10.1 8.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) bZIP_2 PF07716.15 CDJ84241.1 - 3.6e-09 36.5 15.0 3.6e-09 36.5 15.0 2.1 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CDJ84241.1 - 3.4e-08 33.5 17.2 2.2e-07 30.9 16.0 2.5 1 1 1 2 2 2 2 bZIP transcription factor bZIP_Maf PF03131.17 CDJ84241.1 - 5e-06 27.0 15.4 9.8e-06 26.0 15.4 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor CASP_C PF08172.12 CDJ84241.1 - 0.00012 21.5 3.4 0.00017 21.0 3.4 1.2 1 0 0 1 1 1 1 CASP C terminal ZapB PF06005.12 CDJ84241.1 - 0.0017 18.7 8.8 0.0017 18.7 8.8 2.4 2 0 0 2 2 2 1 Cell division protein ZapB V_ATPase_I PF01496.19 CDJ84241.1 - 0.0029 15.6 2.5 0.0037 15.3 2.5 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Fmp27_WPPW PF10359.9 CDJ84241.1 - 0.0083 15.0 0.7 0.011 14.7 0.7 1.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain GAS PF13851.6 CDJ84241.1 - 0.051 12.9 11.2 0.086 12.2 11.2 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding HALZ PF02183.18 CDJ84241.1 - 0.095 12.9 4.8 0.25 11.6 4.8 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper ADIP PF11559.8 CDJ84241.1 - 0.14 12.3 15.4 0.22 11.6 15.4 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TSC22 PF01166.18 CDJ84241.1 - 0.27 11.6 4.8 0.95 9.8 4.8 2.0 1 0 0 1 1 1 0 TSC-22/dip/bun family UPF0242 PF06785.11 CDJ84241.1 - 1 9.4 12.1 1.3 9.1 10.9 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Na_trans_assoc PF06512.13 CDJ84241.1 - 1.1 9.5 7.4 2.2 8.5 7.4 1.4 1 1 0 1 1 1 0 Sodium ion transport-associated Rootletin PF15035.6 CDJ84241.1 - 1.9 8.5 16.6 0.61 10.1 12.7 1.9 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion eRF1_1 PF03463.15 CDJ84242.1 - 1.3e-51 174.0 0.1 2e-51 173.3 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 CDJ84242.1 - 1.7e-31 109.3 0.1 3.3e-31 108.4 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CDJ84242.1 - 4e-23 82.1 0.0 8e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 DUF5492 PF17596.2 CDJ84242.1 - 0.021 15.1 0.0 0.06 13.7 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5492) CbiA PF01656.23 CDJ84242.1 - 0.13 12.3 0.0 0.28 11.3 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PIF1 PF05970.14 CDJ84245.1 - 2.6e-95 319.7 0.0 3.4e-95 319.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 CDJ84245.1 - 6.5e-60 202.6 0.0 6.5e-60 202.6 0.0 3.1 2 1 0 3 3 3 1 Helitron helicase-like domain at N-terminus Viral_helicase1 PF01443.18 CDJ84245.1 - 0.00036 20.4 0.1 0.35 10.6 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.14 CDJ84245.1 - 0.00062 17.8 0.0 0.001 17.2 0.0 1.2 1 0 0 1 1 1 1 Helicase AAA_19 PF13245.6 CDJ84245.1 - 0.00081 19.8 0.0 0.0031 17.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 CDJ84245.1 - 0.00085 19.1 0.0 0.0034 17.2 0.0 2.1 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ResIII PF04851.15 CDJ84245.1 - 0.0009 19.3 0.0 0.0026 17.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MerR PF00376.23 CDJ84247.1 - 0.036 13.8 0.3 0.095 12.5 0.1 1.7 2 0 0 2 2 2 0 MerR family regulatory protein MerR_1 PF13411.6 CDJ84247.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 MerR HTH family regulatory protein Amino_oxidase PF01593.24 CDJ84249.1 - 1.3e-11 44.4 0.0 1.9e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ84249.1 - 1.5e-05 25.1 0.0 3.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TFIIA PF03153.13 CDJ84251.1 - 0.099 12.6 10.6 0.12 12.3 10.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NUC194 PF08163.12 CDJ84251.1 - 0.14 11.1 0.2 0.19 10.6 0.2 1.1 1 0 0 1 1 1 0 NUC194 domain DB PF01682.19 CDJ84252.1 - 4.7e-16 58.9 5.1 4.7e-16 58.9 5.1 2.3 2 0 0 2 2 2 1 DB module DUF4116 PF13475.6 CDJ84252.1 - 0.03 14.0 0.4 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Neur_chan_LBD PF02931.23 CDJ84253.1 - 1.4e-42 145.6 0.1 2e-42 145.1 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ84253.1 - 4.5e-32 112.0 1.3 1.4e-26 94.0 0.0 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region GWT1 PF06423.12 CDJ84253.1 - 1 9.5 2.9 10 6.2 0.0 2.9 2 1 0 2 2 2 0 GWT1 DUF2371 PF10177.9 CDJ84257.1 - 2.2e-12 47.3 1.3 2.1e-11 44.2 1.3 2.1 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2371) Neurensin PF14927.6 CDJ84257.1 - 7.5e-08 32.2 0.1 1.1e-07 31.6 0.1 1.2 1 0 0 1 1 1 1 Neurensin TMEM174 PF15029.6 CDJ84257.1 - 0.0023 17.7 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 2 Transmembrane protein 174 TMEM171 PF15471.6 CDJ84257.1 - 0.38 9.7 2.1 6.5 5.6 2.9 2.0 1 1 1 2 2 2 0 Transmembrane protein family 171 Peptidase_S8 PF00082.22 CDJ84259.1 - 1.6e-73 247.6 4.5 6.7e-46 156.9 0.9 2.1 2 0 0 2 2 2 2 Subtilase family P_proprotein PF01483.20 CDJ84259.1 - 1.1e-47 160.0 2.5 2.8e-26 91.4 0.1 3.1 3 0 0 3 3 3 2 Proprotein convertase P-domain S8_pro-domain PF16470.5 CDJ84259.1 - 5.1e-12 46.4 0.2 1.2e-11 45.2 0.2 1.6 1 0 0 1 1 1 1 Peptidase S8 pro-domain Peptidase_S8 PF00082.22 CDJ84260.1 - 2.9e-47 161.4 2.3 4.9e-47 160.6 2.3 1.4 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 CDJ84260.1 - 3.4e-24 84.7 0.1 6.8e-24 83.7 0.1 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 CDJ84260.1 - 1.1e-14 55.0 4.0 2.7e-14 53.7 4.0 1.7 1 0 0 1 1 1 1 Peptidase S8 pro-domain VSP PF03302.13 CDJ84260.1 - 0.3 9.9 44.3 0.56 9.0 17.2 2.3 1 1 1 2 2 2 0 Giardia variant-specific surface protein 2OG-FeII_Oxy_3 PF13640.6 CDJ84261.1 - 6.7e-12 46.2 0.3 1.3e-11 45.2 0.3 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 CDJ84261.1 - 0.0083 16.2 0.1 0.024 14.7 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat Lig_chan PF00060.26 CDJ84262.1 - 1.2e-57 193.9 0.8 2.5e-57 192.9 0.8 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 CDJ84262.1 - 5.7e-37 126.4 0.0 1.4e-36 125.1 0.0 1.7 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 CDJ84262.1 - 1.3e-26 93.5 0.0 3.4e-26 92.1 0.0 1.7 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 CDJ84262.1 - 4.6e-23 81.9 0.0 2.4e-15 56.5 0.0 2.4 2 0 0 2 2 2 2 Receptor family ligand binding region He_PIG PF05345.12 CDJ84262.1 - 0.00021 21.4 0.0 3 8.1 0.0 3.4 3 0 0 3 3 3 2 Putative Ig domain DUF416 PF04222.12 CDJ84262.1 - 0.019 14.4 0.2 0.95 8.8 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF416) Myb_DNA-bind_3 PF12776.7 CDJ84262.1 - 2.1 9.4 6.3 18 6.4 0.9 3.0 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain RVT_1 PF00078.27 CDJ84263.1 - 1.7e-39 135.6 0.0 3.3e-39 134.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dcc1 PF09724.9 CDJ84264.1 - 3.5e-56 190.9 0.2 4.3e-56 190.6 0.2 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Acp26Ab PF05777.12 CDJ84264.1 - 0.075 13.7 0.0 0.69 10.6 0.0 2.2 2 0 0 2 2 2 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) DCX PF03607.17 CDJ84266.1 - 8.1e-11 41.9 0.0 1.5e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Doublecortin CENP-N PF05238.13 CDJ84266.1 - 0.14 11.4 5.9 0.2 10.9 5.9 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like ArfGap PF01412.18 CDJ84269.1 - 9e-43 145.1 0.6 1.4e-42 144.5 0.6 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf NDC10_II PF16787.5 CDJ84269.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 MOZ_SAS PF01853.18 CDJ84270.1 - 1e-65 220.7 0.0 1.8e-65 219.9 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CDJ84270.1 - 9.5e-21 73.2 2.5 2e-20 72.1 2.5 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 CDJ84270.1 - 2.6e-09 36.8 0.4 1.2e-08 34.7 0.0 2.3 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain IF2_N PF04760.15 CDJ84270.1 - 0.0041 16.9 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Acetyltransf_7 PF13508.7 CDJ84270.1 - 0.027 14.9 0.0 0.062 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDJ84270.1 - 0.088 13.0 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family FR47 PF08445.10 CDJ84270.1 - 0.18 11.8 0.0 0.47 10.5 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein GREB1 PF15782.5 CDJ84270.1 - 5.9 3.9 10.0 8.9 3.3 10.0 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Neur_chan_memb PF02932.16 CDJ84270.1 - 6.5 6.7 6.9 21 5.1 6.9 2.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Caveolin PF01146.17 CDJ84271.1 - 1e-47 161.4 2.7 1.2e-47 161.2 2.7 1.1 1 0 0 1 1 1 1 Caveolin YbgT_YccB PF08173.11 CDJ84271.1 - 0.26 11.4 2.8 0.66 10.2 2.8 1.8 1 1 0 1 1 1 0 Membrane bound YbgT-like protein Peptidase_M10 PF00413.24 CDJ84272.1 - 4.1e-25 88.5 0.0 7.3e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 CDJ84272.1 - 3.4e-22 78.1 5.2 9.2e-10 38.3 0.0 4.5 4 0 0 4 4 4 4 Hemopexin Metallopep PF12044.8 CDJ84272.1 - 0.0054 15.4 0.0 0.007 15.0 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Peptidase_M66 PF10462.9 CDJ84272.1 - 0.014 14.4 0.1 0.021 13.8 0.1 1.1 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.6 CDJ84272.1 - 0.03 14.8 0.0 0.052 14.1 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 CDJ84272.1 - 0.057 13.0 0.4 0.62 9.7 0.2 2.5 3 0 0 3 3 3 0 Astacin (Peptidase family M12A) Peptidase_M54 PF07998.11 CDJ84272.1 - 0.088 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 DUF4953 PF16313.5 CDJ84272.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Met-zincin Kisspeptin PF15152.6 CDJ84272.1 - 0.13 13.1 0.0 0.29 11.9 0.0 1.5 1 0 0 1 1 1 0 Kisspeptin PTPA PF03095.15 CDJ84273.1 - 3.1e-82 276.4 0.0 3.5e-82 276.2 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein TFB6 PF17110.5 CDJ84273.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Homeodomain PF00046.29 CDJ84274.1 - 5.7e-23 80.5 3.5 9.1e-23 79.9 3.5 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ84274.1 - 0.00036 20.4 0.7 0.00061 19.6 0.7 1.5 1 1 0 1 1 1 1 Homeobox KN domain Engrail_1_C_sig PF10525.9 CDJ84274.1 - 0.00043 19.4 0.7 0.00076 18.6 0.7 1.4 1 0 0 1 1 1 1 Engrailed homeobox C-terminal signature domain CENP-B_N PF04218.13 CDJ84274.1 - 0.012 15.2 0.9 0.021 14.5 0.2 1.7 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 CDJ84274.1 - 0.03 14.6 0.4 0.051 13.9 0.2 1.6 1 1 0 1 1 1 0 Transposase HTH_26 PF13443.6 CDJ84274.1 - 0.12 12.8 0.1 2.2 8.8 0.0 2.2 1 1 1 2 2 2 0 Cro/C1-type HTH DNA-binding domain YdaS_antitoxin PF15943.5 CDJ84274.1 - 0.14 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT SOAR PF16533.5 CDJ84275.1 - 9.2e-31 105.8 0.5 9.2e-31 105.8 0.5 3.0 3 1 0 3 3 3 1 STIM1 Orai1-activating region RRM_1 PF00076.22 CDJ84275.1 - 3.1e-13 49.3 0.0 7e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAM_2 PF07647.17 CDJ84275.1 - 5.5e-05 23.2 0.1 0.00015 21.8 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CDJ84275.1 - 0.0042 17.5 0.0 0.0096 16.4 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HemX PF04375.14 CDJ84275.1 - 0.014 14.7 1.8 0.014 14.7 1.8 2.3 3 0 0 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase EF-hand_1 PF00036.32 CDJ84275.1 - 0.14 11.7 0.6 0.33 10.6 0.1 2.0 2 0 0 2 2 2 0 EF hand Coilin_N PF15862.5 CDJ84276.1 - 0.013 15.3 0.2 0.022 14.6 0.2 1.3 1 0 0 1 1 1 0 Coilin N-terminus Bul1_N PF04425.12 CDJ84277.1 - 0.11 11.2 1.3 0.17 10.6 1.3 1.2 1 0 0 1 1 1 0 Bul1 N terminus OAD_gamma PF04277.13 CDJ84277.1 - 2.6 8.7 4.2 8.9 7.0 3.0 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Plug_translocon PF10559.9 CDJ84279.1 - 0.14 12.0 0.1 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 Plug domain of Sec61p Glycos_transf_2 PF00535.26 CDJ84280.1 - 8e-29 100.6 0.1 6.5e-28 97.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CDJ84280.1 - 4.1e-16 59.4 0.2 6.8e-16 58.7 0.2 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 CDJ84280.1 - 1.2e-06 28.0 0.0 2.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CDJ84280.1 - 0.0033 16.9 0.0 0.0093 15.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CDJ84280.1 - 0.073 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Glycosyl transferase family group 2 GARS_C PF02843.16 CDJ84280.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, C domain EMP24_GP25L PF01105.24 CDJ84281.1 - 7.8e-55 185.6 0.1 8.9e-55 185.5 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD adh_short PF00106.25 CDJ84282.1 - 8.6e-32 110.2 0.7 9.7e-24 83.9 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ84282.1 - 3.6e-20 72.5 0.1 9.2e-19 67.9 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ84282.1 - 3.2e-11 43.5 0.1 5.7e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDJ84282.1 - 1.2e-07 31.5 0.0 1.8e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 CDJ84282.1 - 0.00011 22.5 0.1 0.00078 19.7 0.1 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 CDJ84282.1 - 0.00085 18.8 0.0 0.0015 18.0 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 CDJ84282.1 - 0.0047 16.8 0.1 0.041 13.8 0.0 2.4 2 1 1 3 3 3 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CDJ84282.1 - 0.019 14.2 0.5 0.29 10.3 0.5 2.6 1 1 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.15 CDJ84282.1 - 0.034 13.3 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF4061 PF13270.6 CDJ84282.1 - 0.084 13.2 0.1 0.26 11.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) Spec3 PF15795.5 CDJ84285.1 - 2.2e-31 108.3 6.2 3.3e-31 107.7 6.2 1.3 1 0 0 1 1 1 1 Ectodermal ciliogenesis protein Collagen PF01391.18 CDJ84286.1 - 7e-23 80.2 84.2 1.9e-09 37.2 28.2 4.2 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ84286.1 - 1.1e-06 28.6 1.3 1.5e-06 28.1 1.3 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Ank_2 PF12796.7 CDJ84287.1 - 1.4e-55 185.8 9.0 2.5e-11 44.0 0.0 11.2 7 2 6 13 13 13 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ84287.1 - 8e-35 118.8 15.6 5.7e-07 30.0 0.1 13.5 6 2 8 15 15 15 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ84287.1 - 1.2e-32 108.2 20.5 0.011 16.2 0.1 15.4 16 0 0 16 16 16 9 Ankyrin repeat Ank_5 PF13857.6 CDJ84287.1 - 1.2e-31 108.4 16.6 0.00013 22.2 0.0 13.4 11 3 3 14 14 14 9 Ankyrin repeats (many copies) Ank PF00023.30 CDJ84287.1 - 8e-28 95.6 15.2 0.0061 17.0 0.0 13.7 14 0 0 14 14 14 9 Ankyrin repeat 2-Hacid_dh_C PF02826.19 CDJ84288.1 - 2.8e-53 179.9 0.0 4e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CDJ84288.1 - 6.7e-25 87.3 0.0 1e-24 86.7 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CDJ84288.1 - 0.00021 21.5 0.0 0.00068 19.8 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Polyoma_lg_T_C PF06431.11 CDJ84288.1 - 0.12 11.3 0.1 0.16 10.8 0.1 1.1 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus AAA PF00004.29 CDJ84290.1 - 3.1e-45 153.8 0.0 7.7e-42 142.8 0.0 3.3 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ84290.1 - 3.4e-10 39.6 1.1 1.5e-07 31.1 0.1 2.6 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 CDJ84290.1 - 1.7e-09 38.3 0.1 0.011 16.1 0.0 3.5 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CDJ84290.1 - 9.6e-07 29.1 0.0 0.012 15.8 0.0 3.5 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 CDJ84290.1 - 2.7e-06 27.2 0.0 0.00039 20.2 0.0 3.2 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CDJ84290.1 - 1.2e-05 25.4 0.0 0.047 13.7 0.0 3.5 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CDJ84290.1 - 2.5e-05 24.3 0.1 0.00097 19.2 0.0 3.1 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.6 CDJ84290.1 - 3.2e-05 24.5 0.0 0.042 14.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 CDJ84290.1 - 3.8e-05 23.7 0.6 6 6.8 0.0 4.0 3 1 1 4 4 4 0 NACHT domain RNA_helicase PF00910.22 CDJ84290.1 - 8.4e-05 22.9 0.0 0.017 15.5 0.0 3.2 3 0 0 3 3 3 1 RNA helicase Mg_chelatase PF01078.21 CDJ84290.1 - 8.8e-05 22.0 0.2 0.044 13.2 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 CDJ84290.1 - 0.00019 21.0 0.2 0.28 10.7 0.1 3.4 2 1 2 4 4 4 1 AAA domain AAA_33 PF13671.6 CDJ84290.1 - 0.00024 21.3 0.0 0.093 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CDJ84290.1 - 0.00026 20.3 0.7 0.069 12.3 0.0 3.2 3 0 0 3 3 3 1 TIP49 P-loop domain Zeta_toxin PF06414.12 CDJ84290.1 - 0.00031 20.1 0.0 0.14 11.5 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin Sigma54_activat PF00158.26 CDJ84290.1 - 0.00032 20.4 0.0 0.57 9.9 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_2 PF07724.14 CDJ84290.1 - 0.00035 20.7 0.0 0.0038 17.3 0.0 2.7 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 CDJ84290.1 - 0.00055 19.7 0.0 0.042 13.6 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein NB-ARC PF00931.22 CDJ84290.1 - 0.0014 17.9 0.1 0.79 8.9 0.0 3.7 4 0 0 4 4 4 1 NB-ARC domain TsaE PF02367.17 CDJ84290.1 - 0.0022 18.0 0.0 0.16 11.9 0.0 2.8 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 CDJ84290.1 - 0.0024 17.4 0.0 1.2 8.6 0.1 2.4 2 0 0 2 2 2 1 PhoH-like protein Sigma54_activ_2 PF14532.6 CDJ84290.1 - 0.0027 17.8 0.1 2.7 8.1 0.0 3.1 3 0 0 3 3 2 1 Sigma-54 interaction domain DUF815 PF05673.13 CDJ84290.1 - 0.0028 16.9 0.0 0.013 14.6 0.0 2.1 3 0 0 3 3 2 1 Protein of unknown function (DUF815) Torsin PF06309.11 CDJ84290.1 - 0.0032 17.6 0.0 0.87 9.7 0.0 2.8 2 0 0 2 2 2 1 Torsin AAA_28 PF13521.6 CDJ84290.1 - 0.0048 17.2 0.0 0.7 10.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 CDJ84290.1 - 0.008 16.3 0.0 0.088 12.9 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family Rad17 PF03215.15 CDJ84290.1 - 0.02 14.8 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain ATPase PF06745.13 CDJ84290.1 - 0.02 14.2 0.1 2.7 7.3 0.0 3.0 2 1 1 3 3 3 0 KaiC AAA_17 PF13207.6 CDJ84290.1 - 0.025 15.0 0.0 0.23 11.9 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 CDJ84290.1 - 0.025 14.1 0.0 0.82 9.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 CDJ84290.1 - 0.09 12.7 0.2 10 6.0 0.0 3.0 3 0 0 3 3 2 0 NTPase AAA_19 PF13245.6 CDJ84290.1 - 0.18 12.1 0.1 7.9 6.8 0.0 3.2 4 0 0 4 4 3 0 AAA domain Neur_chan_LBD PF02931.23 CDJ84291.1 - 7.1e-44 149.8 0.0 8.4e-44 149.6 0.0 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Sec1 PF00995.23 CDJ84292.1 - 2.5e-121 406.7 1.1 2.9e-121 406.5 1.1 1.0 1 0 0 1 1 1 1 Sec1 family EFTUD2 PF16004.5 CDJ84293.1 - 6.7e-38 130.0 10.6 8.6e-38 129.7 10.6 1.1 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Roughex PF06020.11 CDJ84293.1 - 0.027 13.6 1.9 0.037 13.1 1.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF3533 PF12051.8 CDJ84293.1 - 0.091 11.7 0.1 0.13 11.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) CS PF04969.16 CDJ84294.1 - 0.018 16.1 0.1 0.026 15.5 0.1 1.3 1 0 0 1 1 1 0 CS domain tRNA-synt_2 PF00152.20 CDJ84295.1 - 7.6e-74 248.6 0.0 1e-73 248.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CDJ84295.1 - 8.1e-13 48.2 0.0 1.8e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CDJ84295.1 - 4.5e-09 36.2 0.0 0.00051 19.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Peptidase_C2 PF00648.21 CDJ84296.1 - 8.1e-100 333.7 0.0 1.1e-99 333.3 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease CSD PF00313.22 CDJ84297.1 - 7.2e-23 80.2 0.3 1.4e-22 79.3 0.3 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 CDJ84297.1 - 0.00011 21.8 0.2 0.00027 20.5 0.2 1.6 1 0 0 1 1 1 1 Ribonuclease B OB domain zf-CCHC PF00098.23 CDJ84297.1 - 0.055 13.6 12.9 0.76 10.0 0.6 2.9 2 1 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ84297.1 - 0.24 11.2 6.6 1.7 8.5 1.0 2.4 2 0 0 2 2 2 0 Zinc knuckle EF-hand_7 PF13499.6 CDJ84298.1 - 2.5e-10 40.7 3.3 1.1e-09 38.6 0.3 2.7 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ84298.1 - 5.9e-09 35.1 0.6 5.8e-06 25.8 0.0 4.1 4 2 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 CDJ84298.1 - 8.8e-08 31.9 4.8 7.9e-05 22.4 0.2 2.7 1 1 1 2 2 2 2 EF-hand domain pair EFhand_Ca_insen PF08726.10 CDJ84298.1 - 1e-05 25.5 0.8 0.0015 18.6 0.1 3.0 3 0 0 3 3 3 1 Ca2+ insensitive EF hand EF-hand_1 PF00036.32 CDJ84298.1 - 0.00035 19.9 3.5 0.042 13.4 0.0 3.8 3 1 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 CDJ84298.1 - 0.00045 20.5 0.1 0.047 14.0 0.0 2.8 2 1 0 2 2 2 1 EF-hand domain TRCF PF03461.15 CDJ84298.1 - 0.00082 19.7 0.3 0.42 11.0 0.0 2.2 2 0 0 2 2 2 2 TRCF domain UPF0154 PF03672.13 CDJ84298.1 - 0.0035 17.3 0.0 0.54 10.3 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) EF-hand_14 PF17959.1 CDJ84298.1 - 0.0058 16.9 1.0 0.068 13.5 0.2 2.1 2 0 0 2 2 2 1 EF-hand domain DUF3085 PF11284.8 CDJ84298.1 - 0.028 14.7 0.1 0.055 13.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3085) LPD11 PF18824.1 CDJ84298.1 - 0.063 13.4 0.3 1.8 8.7 0.1 2.5 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 RsmJ PF04378.13 CDJ84298.1 - 0.098 11.9 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ SRP54_N PF02881.19 CDJ84298.1 - 0.12 12.6 1.6 1.9 8.8 0.3 2.5 2 1 1 3 3 3 0 SRP54-type protein, helical bundle domain Methyltransf_16 PF10294.9 CDJ84299.1 - 2.8e-25 89.1 0.1 4.5e-25 88.4 0.1 1.4 1 0 0 1 1 1 1 Lysine methyltransferase FAM86 PF14904.6 CDJ84299.1 - 1.7e-06 28.0 0.7 4.3e-06 26.7 0.2 1.9 2 0 0 2 2 2 1 Family of unknown function Methyltransf_25 PF13649.6 CDJ84299.1 - 2.7e-05 24.8 0.0 5.6e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ84299.1 - 4.7e-05 23.0 0.0 7.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 CDJ84299.1 - 0.00026 20.8 0.0 0.00047 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ84299.1 - 0.00028 21.6 0.0 0.00063 20.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 CDJ84299.1 - 0.027 13.8 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G AlaDh_PNT_C PF01262.21 CDJ84299.1 - 0.043 13.1 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIT_SHD PF08518.11 CDJ84299.1 - 0.047 13.3 0.3 0.047 13.3 0.3 1.9 2 0 0 2 2 2 0 Spa2 homology domain (SHD) of GIT PrmA PF06325.13 CDJ84299.1 - 0.077 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MA3 PF02847.17 CDJ84299.1 - 0.096 12.7 0.2 0.33 10.9 0.2 1.9 2 0 0 2 2 2 0 MA3 domain DUF938 PF06080.12 CDJ84299.1 - 0.2 11.4 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Complex1_LYR PF05347.15 CDJ84300.1 - 1e-12 47.9 1.0 1.4e-12 47.5 0.2 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CDJ84300.1 - 0.0083 16.8 1.0 0.012 16.4 1.0 1.4 1 1 0 1 1 1 1 Complex1_LYR-like PTPA PF03095.15 CDJ84301.1 - 9.8e-104 347.0 0.3 1.2e-103 346.8 0.3 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Aph-1 PF06105.12 CDJ84301.1 - 0.021 14.2 0.1 0.033 13.6 0.1 1.2 1 0 0 1 1 1 0 Aph-1 protein SET PF00856.28 CDJ84302.1 - 3.6e-13 50.2 0.0 9.7e-13 48.8 0.0 1.7 1 1 0 1 1 1 1 SET domain FAM76 PF16046.5 CDJ84302.1 - 0.059 12.7 0.5 0.097 12.0 0.5 1.2 1 0 0 1 1 1 0 FAM76 protein DUF2688 PF10892.8 CDJ84302.1 - 0.12 11.8 2.8 2.2 7.8 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2688) G10 PF01125.17 CDJ84303.1 - 1.1e-65 219.9 4.2 1.2e-65 219.7 4.2 1.0 1 0 0 1 1 1 1 G10 protein SAP PF02037.27 CDJ84304.1 - 1.8e-11 43.5 1.8 4e-11 42.4 1.8 1.7 1 0 0 1 1 1 1 SAP domain MMS19_C PF12460.8 CDJ84305.1 - 0.0024 17.1 0.3 0.22 10.6 0.1 2.2 1 1 1 2 2 2 2 RNAPII transcription regulator C-terminal Ipi1_N PF12333.8 CDJ84305.1 - 0.007 16.9 0.0 0.007 16.9 0.0 2.6 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation Cnd1 PF12717.7 CDJ84305.1 - 0.013 15.6 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CDJ84305.1 - 0.02 15.4 0.0 2.3 8.8 0.0 2.7 2 1 1 3 3 3 0 HEAT-like repeat YfhO PF09586.10 CDJ84306.1 - 0.017 13.4 4.9 0.019 13.2 4.9 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO ABC_membrane PF00664.23 CDJ84307.1 - 4.9e-36 124.8 14.0 4.9e-36 124.8 14.0 2.0 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ84307.1 - 1.6e-32 112.9 0.0 3e-32 112.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CDJ84307.1 - 3.7e-05 23.3 0.0 0.0004 19.9 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain MTABC_N PF16185.5 CDJ84307.1 - 0.0011 18.5 0.4 0.0011 18.5 0.4 3.0 3 1 1 4 4 4 1 Mitochondrial ABC-transporter N-terminal five TM region AAA_21 PF13304.6 CDJ84307.1 - 0.0024 17.7 0.1 0.0066 16.3 0.1 1.8 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CDJ84307.1 - 0.0027 17.6 0.0 0.0052 16.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 CDJ84307.1 - 0.0031 17.9 0.1 0.0088 16.4 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CDJ84307.1 - 0.0036 17.6 0.0 0.032 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CDJ84307.1 - 0.022 14.5 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 CDJ84307.1 - 0.024 14.9 0.4 0.4 10.9 0.4 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit End_beta_barrel PF12195.8 CDJ84307.1 - 0.077 13.0 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 Beta barrel domain of bacteriophage endosialidase AAA PF00004.29 CDJ84307.1 - 0.18 12.3 0.0 1.2 9.5 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_membrane PF00664.23 CDJ84308.1 - 2.4e-36 125.8 14.0 3e-36 125.5 14.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ84308.1 - 1e-32 113.5 0.0 2.1e-32 112.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CDJ84308.1 - 2.2e-05 24.0 0.0 0.00037 20.0 0.0 2.0 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain MTABC_N PF16185.5 CDJ84308.1 - 0.00088 18.8 0.3 0.00088 18.8 0.3 2.2 2 1 1 3 3 3 1 Mitochondrial ABC-transporter N-terminal five TM region AAA_21 PF13304.6 CDJ84308.1 - 0.0016 18.3 0.1 0.0061 16.4 0.1 1.8 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CDJ84308.1 - 0.0019 18.1 0.0 0.0037 17.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 CDJ84308.1 - 0.002 18.6 0.1 0.0064 16.9 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CDJ84308.1 - 0.0022 18.3 0.0 0.024 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 CDJ84308.1 - 0.015 15.5 0.5 0.32 11.3 0.5 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 CDJ84308.1 - 0.016 14.9 0.0 0.04 13.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain End_beta_barrel PF12195.8 CDJ84308.1 - 0.055 13.4 0.1 0.16 12.0 0.1 1.7 1 0 0 1 1 1 0 Beta barrel domain of bacteriophage endosialidase AAA PF00004.29 CDJ84308.1 - 0.11 13.0 0.0 0.84 10.1 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDJ84308.1 - 0.11 12.5 0.1 2.6 8.1 0.1 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DHO_dh PF01180.21 CDJ84311.1 - 4.7e-35 121.2 0.0 7.9e-35 120.5 0.0 1.4 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase Fer4_21 PF14697.6 CDJ84311.1 - 1.1e-22 80.0 15.5 2.7e-22 78.7 12.9 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 CDJ84311.1 - 1.2e-07 31.5 16.7 0.00052 20.0 2.2 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 CDJ84311.1 - 2e-07 30.7 13.6 0.0013 18.7 3.7 2.9 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 CDJ84311.1 - 3.4e-07 30.3 9.8 8.7e-07 29.0 9.8 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Dus PF01207.17 CDJ84311.1 - 3.5e-07 29.6 0.0 2e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Fer4_7 PF12838.7 CDJ84311.1 - 1.3e-06 28.8 11.5 1.3e-06 28.8 11.5 2.2 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 CDJ84311.1 - 4e-06 26.4 20.7 0.00032 20.4 4.5 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 CDJ84311.1 - 0.00012 22.1 13.1 0.0003 20.9 13.1 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox_2 PF07992.14 CDJ84311.1 - 0.00055 19.2 0.1 0.00087 18.6 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_17 PF13534.6 CDJ84311.1 - 0.0044 17.5 7.1 0.48 11.0 1.1 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 CDJ84311.1 - 0.0052 17.2 15.3 0.19 12.3 2.9 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_22 PF17179.4 CDJ84311.1 - 0.0064 17.3 5.7 1.4 9.8 0.8 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 CDJ84311.1 - 0.017 15.7 14.8 0.29 11.7 3.3 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I NMO PF03060.15 CDJ84311.1 - 0.019 14.3 4.5 0.037 13.4 4.0 1.6 1 1 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.21 CDJ84311.1 - 0.13 11.7 0.0 0.41 10.1 0.0 1.8 1 0 0 1 1 1 0 Histidine biosynthesis protein Fer4_8 PF13183.6 CDJ84311.1 - 1 9.9 15.1 3.8 8.0 4.7 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 CDJ84311.1 - 1.3 9.8 10.1 2.3 9.0 2.0 3.5 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_16 PF13484.6 CDJ84311.1 - 1.4 9.9 14.7 1.6 9.7 3.1 2.6 1 1 2 3 3 3 0 4Fe-4S double cluster binding domain 7TM_GPCR_Srd PF10317.9 CDJ84313.1 - 2.8e-19 69.4 2.4 3.2e-19 69.2 2.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Str PF10326.9 CDJ84313.1 - 1.8e-09 37.4 2.5 2e-09 37.2 2.5 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srj PF10319.9 CDJ84313.1 - 3.5e-07 29.9 1.3 4.2e-07 29.6 1.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Srh PF10318.9 CDJ84313.1 - 1.3e-05 24.4 0.5 1.5e-05 24.2 0.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Srd PF10317.9 CDJ84314.1 - 8.3e-20 71.2 3.3 1e-19 70.8 3.3 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Srj PF10319.9 CDJ84314.1 - 0.001 18.5 1.0 0.0013 18.2 1.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj Virul_fac_BrkB PF03631.15 CDJ84314.1 - 0.0051 16.5 1.7 0.0059 16.3 1.7 1.1 1 0 0 1 1 1 1 Virulence factor BrkB 7TM_GPCR_Str PF10326.9 CDJ84314.1 - 0.011 15.2 2.7 0.013 14.9 2.7 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str ABC_export PF16962.5 CDJ84314.1 - 0.011 14.3 0.8 0.013 14.0 0.8 1.1 1 0 0 1 1 1 0 Putative ABC exporter DUF2776 PF10951.8 CDJ84314.1 - 0.021 14.1 0.1 0.027 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2776) DUF1600 PF07667.11 CDJ84314.1 - 0.11 12.7 4.5 0.11 12.6 3.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1600) Dus PF01207.17 CDJ84317.1 - 7.4e-66 222.3 0.0 9.1e-66 222.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.17 CDJ84317.1 - 0.0048 16.3 0.0 0.0067 15.8 0.0 1.2 1 0 0 1 1 1 1 Thiamine monophosphate synthase His_biosynth PF00977.21 CDJ84317.1 - 0.0087 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 CDJ84317.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Methyltransf_28 PF02636.17 CDJ84318.1 - 3e-60 204.1 0.0 4e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Metallophos_2 PF12850.7 CDJ84318.1 - 1.1e-20 74.5 0.1 1.8e-20 73.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 CDJ84318.1 - 0.0036 17.8 0.2 2.5 8.6 0.1 2.5 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Nif11 PF07862.11 CDJ84318.1 - 0.18 12.1 0.0 0.45 10.9 0.0 1.7 1 0 0 1 1 1 0 Nif11 domain MGC-24 PF05283.11 CDJ84319.1 - 0.025 15.0 7.3 0.042 14.3 7.3 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PSI PF01437.25 CDJ84319.1 - 1.7 9.2 13.2 4.3 7.9 13.2 1.7 1 0 0 1 1 1 0 Plexin repeat Astacin PF01400.24 CDJ84320.1 - 6.2e-73 244.5 0.0 8.7e-73 244.0 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) ShK PF01549.24 CDJ84320.1 - 3e-06 27.7 7.9 7.2e-06 26.4 7.9 1.7 1 0 0 1 1 1 1 ShK domain-like PDZ PF00595.24 CDJ84321.1 - 0.0021 18.4 0.4 0.0055 17.0 0.4 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ84321.1 - 0.0089 16.3 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Hpr_kinase_C PF07475.12 CDJ84321.1 - 0.021 14.4 0.2 0.035 13.6 0.2 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain PDZ_6 PF17820.1 CDJ84321.1 - 0.08 12.8 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 PDZ domain DUF4444 PF14563.6 CDJ84322.1 - 0.092 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4444) E_raikovi_mat PF06360.11 CDJ84322.1 - 0.31 11.5 6.8 0.77 10.2 2.7 3.2 3 0 0 3 3 3 0 Euplotes raikovi mating pheromone Helicase_C PF00271.31 CDJ84323.1 - 9.6e-13 48.5 0.0 3.2e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 CDJ84323.1 - 1.1e-11 45.2 2.2 3.6e-11 43.6 2.2 1.9 1 0 0 1 1 1 1 RecQ zinc-binding KIX_2 PF16987.5 CDJ84323.1 - 0.24 11.4 3.0 0.31 11.1 0.1 2.6 3 1 1 4 4 4 0 KIX domain DEAD PF00270.29 CDJ84324.1 - 6.7e-21 74.8 0.1 6.3e-19 68.4 0.0 2.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ84324.1 - 0.00064 19.8 0.0 0.0018 18.3 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDJ84324.1 - 0.09 13.1 0.0 0.34 11.3 0.0 1.9 2 0 0 2 2 2 0 Helicase conserved C-terminal domain FAT PF02259.23 CDJ84325.1 - 1.3e-21 77.3 4.3 2.1e-21 76.5 4.3 1.4 1 0 0 1 1 1 1 FAT domain UME PF08064.13 CDJ84325.1 - 1.3e-08 34.6 3.3 2.9e-05 23.9 0.0 3.8 3 0 0 3 3 3 2 UME (NUC010) domain PI3_PI4_kinase PF00454.27 CDJ84325.1 - 5.8e-05 23.0 0.1 0.00013 21.8 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TPR_19 PF14559.6 CDJ84325.1 - 0.0075 16.8 0.3 0.041 14.4 0.3 2.4 1 0 0 1 1 1 1 Tetratricopeptide repeat EF-hand_2 PF09068.11 CDJ84326.1 - 1.8 8.7 5.0 34 4.6 1.8 3.0 2 1 1 3 3 3 0 EF hand PI3_PI4_kinase PF00454.27 CDJ84327.1 - 2.9e-36 125.6 0.0 4.5e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CDJ84327.1 - 3.6e-13 49.1 0.0 5.7e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 FATC domain GTP_EFTU PF00009.27 CDJ84328.1 - 6.4e-56 189.0 0.0 9.2e-56 188.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CDJ84328.1 - 6.1e-41 139.2 0.0 1.5e-40 138.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CDJ84328.1 - 4.8e-15 55.7 1.5 1e-14 54.6 0.3 2.3 2 1 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDJ84328.1 - 0.00015 21.9 0.1 0.0035 17.4 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 CDJ84328.1 - 0.0094 15.8 0.2 0.0094 15.8 0.2 2.1 3 0 0 3 3 3 1 Elongation factor Tu domain 4 NIF3 PF01784.18 CDJ84328.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) Semialdhyde_dhC PF02774.18 CDJ84328.1 - 0.018 15.1 0.1 0.078 13.0 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain UCH_1 PF13423.6 CDJ84329.1 - 3.8e-31 108.9 0.0 7.2e-31 108.0 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 CDJ84329.1 - 3.4e-18 66.7 0.0 7e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 CDJ84329.1 - 0.00093 18.8 0.0 0.0037 16.8 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-CCCH_2 PF14608.6 CDJ84329.1 - 0.63 10.6 7.5 0.068 13.7 2.5 2.1 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger ERCC3_RAD25_C PF16203.5 CDJ84330.1 - 4.4e-119 396.2 3.3 8.5e-119 395.3 3.3 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 CDJ84330.1 - 5.2e-39 133.3 0.0 9.9e-39 132.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ84330.1 - 1.6e-17 64.1 0.0 4.9e-17 62.4 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDJ84330.1 - 3.8e-13 49.8 4.0 4e-12 46.5 0.3 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 CDJ84330.1 - 0.0036 16.1 0.0 0.0055 15.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Sigma54_activat PF00158.26 CDJ84330.1 - 0.054 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain HTH_26 PF13443.6 CDJ84336.1 - 0.0011 19.3 0.1 0.0021 18.5 0.1 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_IclR PF09339.10 CDJ84336.1 - 0.0033 17.2 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 CDJ84336.1 - 0.0055 16.6 0.2 0.01 15.7 0.2 1.5 1 1 0 1 1 1 1 MarR family DUF3602 PF12223.8 CDJ84336.1 - 0.022 15.4 1.0 0.022 15.4 1.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3602) HTH_3 PF01381.22 CDJ84336.1 - 0.1 12.6 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix Collagen PF01391.18 CDJ84337.1 - 6.1e-22 77.1 109.8 0.0001 22.0 8.5 4.2 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ84337.1 - 8.3e-18 64.2 0.3 1e-17 63.9 0.3 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain ABC_tran PF00005.27 CDJ84338.1 - 2.6e-69 232.0 0.1 1.7e-33 116.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CDJ84338.1 - 1e-66 225.4 27.2 1e-44 153.3 11.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 CDJ84338.1 - 4.5e-15 55.7 2.5 3.6e-05 23.3 0.0 4.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDJ84338.1 - 4.7e-09 36.9 4.1 0.00043 20.7 0.4 3.1 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CDJ84338.1 - 5.9e-09 36.3 0.4 0.00038 20.7 0.1 3.4 3 1 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 CDJ84338.1 - 6.8e-09 35.8 0.8 0.00095 19.1 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CDJ84338.1 - 4.7e-08 32.6 0.6 0.0094 15.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 CDJ84338.1 - 1.6e-07 31.3 0.5 0.0042 16.8 0.0 3.1 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CDJ84338.1 - 1.6e-06 28.7 0.1 0.11 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 CDJ84338.1 - 2.5e-06 27.5 0.3 0.32 10.7 0.1 3.5 3 1 1 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 CDJ84338.1 - 5.3e-06 26.5 0.5 0.55 10.2 0.0 4.2 4 1 1 5 5 5 2 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CDJ84338.1 - 7.3e-06 25.8 0.0 0.017 14.9 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 CDJ84338.1 - 7.6e-06 26.4 0.1 0.036 14.5 0.0 3.7 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CDJ84338.1 - 2.9e-05 24.4 0.1 0.31 11.3 0.1 2.6 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 CDJ84338.1 - 3.3e-05 22.9 1.0 0.0085 14.9 0.0 2.9 4 0 0 4 4 3 1 Predicted ATPase of the ABC class G-alpha PF00503.20 CDJ84338.1 - 0.0001 21.6 0.0 0.18 10.9 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 CDJ84338.1 - 0.00019 21.5 0.2 0.83 9.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.6 CDJ84338.1 - 0.0002 21.6 0.0 1.1 9.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 CDJ84338.1 - 0.00041 20.5 1.2 0.42 10.7 0.2 2.8 3 0 0 3 3 2 1 Helicase HerA, central domain SbcCD_C PF13558.6 CDJ84338.1 - 0.00053 20.2 2.8 1.8 8.8 0.1 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 CDJ84338.1 - 0.00086 19.3 0.1 2.8 8.0 0.0 4.0 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.6 CDJ84338.1 - 0.00097 18.8 0.0 0.41 10.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 CDJ84338.1 - 0.00099 18.9 0.1 0.27 11.0 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.20 CDJ84338.1 - 0.0015 18.4 0.1 1.8 8.4 0.0 2.8 3 0 0 3 3 2 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 CDJ84338.1 - 0.0017 17.6 1.9 0.99 8.6 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin AAA_17 PF13207.6 CDJ84338.1 - 0.0021 18.5 0.4 6.7 7.1 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 CDJ84338.1 - 0.0021 17.8 0.2 1.4 8.5 0.0 2.4 3 0 0 3 3 2 1 AAA ATPase domain ATP_bind_1 PF03029.17 CDJ84338.1 - 0.0029 17.4 0.1 2.4 7.9 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 CDJ84338.1 - 0.003 17.1 0.0 0.8 9.2 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 CDJ84338.1 - 0.0052 16.0 0.0 2.4 7.3 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Ploopntkinase3 PF18751.1 CDJ84338.1 - 0.0053 16.7 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 Cytidylate_kin PF02224.18 CDJ84338.1 - 0.0065 16.2 0.1 0.54 10.0 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase RNA_helicase PF00910.22 CDJ84338.1 - 0.0066 16.8 0.1 3.7 8.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase dNK PF01712.19 CDJ84338.1 - 0.0085 16.0 0.1 4.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase Rad17 PF03215.15 CDJ84338.1 - 0.0095 15.9 0.1 1.8 8.4 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain Mg_chelatase PF01078.21 CDJ84338.1 - 0.011 15.2 0.1 4.2 6.7 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 CDJ84338.1 - 0.011 15.6 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 NACHT domain MeaB PF03308.16 CDJ84338.1 - 0.011 14.7 0.1 0.92 8.4 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 CDJ84338.1 - 0.015 15.8 1.1 4.4 7.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 CDJ84338.1 - 0.017 15.0 0.4 5.2 6.9 0.0 2.9 3 0 0 3 3 2 0 NTPase SRP54 PF00448.22 CDJ84338.1 - 0.018 14.7 0.1 4.3 6.9 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Septin PF00735.18 CDJ84338.1 - 0.021 14.1 0.0 4.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Septin FtsK_SpoIIIE PF01580.18 CDJ84338.1 - 0.033 13.5 0.2 4.1 6.7 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family TsaE PF02367.17 CDJ84338.1 - 0.033 14.2 0.0 9.4 6.3 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 CDJ84338.1 - 0.036 13.1 0.0 9.2 5.2 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein TniB PF05621.11 CDJ84338.1 - 0.037 13.4 0.0 10 5.5 0.0 3.5 4 0 0 4 4 4 0 Bacterial TniB protein IstB_IS21 PF01695.17 CDJ84338.1 - 0.038 13.7 0.2 20 4.8 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 CDJ84338.1 - 0.038 13.6 0.0 8.6 6.0 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.13 CDJ84338.1 - 0.039 13.1 0.0 4.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Roc PF08477.13 CDJ84338.1 - 0.044 14.0 0.1 18 5.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_PrkA PF08298.11 CDJ84338.1 - 0.047 12.6 0.0 6.5 5.6 0.0 2.3 2 0 0 2 2 2 0 PrkA AAA domain AAA_19 PF13245.6 CDJ84338.1 - 0.066 13.6 0.0 5.2 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 CDJ84338.1 - 0.077 12.2 0.0 5.8 6.0 0.0 2.5 2 0 0 2 2 2 0 KAP family P-loop domain Dynamin_N PF00350.23 CDJ84338.1 - 0.082 13.0 1.7 3.5 7.7 0.1 2.5 2 0 0 2 2 2 0 Dynamin family ECH_2 PF16113.5 CDJ84338.1 - 0.13 11.7 0.1 3.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase Pox_A32 PF04665.12 CDJ84338.1 - 0.16 11.4 0.3 9.3 5.6 0.1 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein PhoR PF11808.8 CDJ84338.1 - 0.3 11.5 2.7 1.4 9.4 0.4 3.1 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR Fcf2 PF08698.11 CDJ84339.1 - 8.5e-33 112.6 0.6 2.9e-32 110.9 0.6 1.9 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Kinesin PF00225.23 CDJ84341.1 - 6.5e-110 367.2 0.0 1e-109 366.5 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 CDJ84341.1 - 1.8e-53 181.3 7.1 3e-43 148.1 0.8 2.9 1 1 1 2 2 2 2 Kinesin-associated DUF3694 PF12473.8 CDJ84341.1 - 2.3e-34 119.3 0.0 5.5e-34 118.1 0.0 1.7 1 0 0 1 1 1 1 Kinesin protein Microtub_bd PF16796.5 CDJ84341.1 - 9.7e-23 80.8 0.0 2.9e-22 79.2 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 CDJ84341.1 - 6.9e-13 48.8 1.6 5.6e-10 39.5 1.5 3.1 2 0 0 2 2 2 1 Kinesin protein 1B PH PF00169.29 CDJ84341.1 - 4.1e-11 43.3 0.0 2.6e-10 40.7 0.0 2.4 2 0 0 2 2 2 1 PH domain FHA PF00498.26 CDJ84341.1 - 6.5e-06 26.4 0.0 3.9e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 FHA domain PH_11 PF15413.6 CDJ84341.1 - 0.0065 16.9 0.0 0.022 15.2 0.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain CKS PF01111.19 CDJ84341.1 - 0.029 14.6 0.2 0.84 10.0 0.0 2.8 2 0 0 2 2 2 0 Cyclin-dependent kinase regulatory subunit DUF732 PF05305.14 CDJ84341.1 - 0.21 12.0 0.6 3.8 8.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF732) PNMA PF14893.6 CDJ84342.1 - 0.0021 17.6 0.0 0.0026 17.2 0.0 1.0 1 0 0 1 1 1 1 PNMA DUF4882 PF16223.5 CDJ84342.1 - 0.16 11.2 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4882) DUF1794 PF08768.11 CDJ84343.1 - 4e-31 108.0 0.0 4.8e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) ShK PF01549.24 CDJ84343.1 - 1.4e-05 25.5 10.6 2.2e-05 24.9 10.6 1.3 1 0 0 1 1 1 1 ShK domain-like Exo_endo_phos PF03372.23 CDJ84344.1 - 0.00043 19.9 0.0 0.00066 19.3 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CDJ84344.1 - 0.0022 17.8 0.0 0.0056 16.5 0.0 1.6 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase RhoGEF PF00621.20 CDJ84345.1 - 4e-26 92.4 0.9 9.6e-26 91.1 0.7 1.7 2 0 0 2 2 2 1 RhoGEF domain DUF1133 PF06576.11 CDJ84345.1 - 0.064 12.6 0.2 0.14 11.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) Collagen PF01391.18 CDJ84346.1 - 2.9e-21 75.0 92.3 3.8e-10 39.4 40.4 3.9 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Integrase_H2C2 PF17921.1 CDJ84347.1 - 3.3e-05 23.9 0.3 7.4e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain Asp PF00026.23 CDJ84348.1 - 2.8e-83 280.0 0.4 3.3e-83 279.7 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ84348.1 - 3.9e-11 43.5 7.2 1.4e-09 38.4 6.1 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ84348.1 - 3.1e-07 30.3 0.0 1.2e-06 28.3 0.0 2.1 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Collagen PF01391.18 CDJ84349.1 - 2.2e-21 75.4 113.8 1.1e-08 34.7 46.0 3.9 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Collagen PF01391.18 CDJ84350.1 - 9.5e-25 86.1 92.1 3.2e-09 36.4 34.5 4.2 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Collagen PF01391.18 CDJ84351.1 - 9.3e-22 76.6 101.8 2.4e-06 27.2 42.1 4.0 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ84351.1 - 1.1e-17 63.8 0.8 1.5e-17 63.4 0.8 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain DUF1758 PF05585.12 CDJ84352.1 - 5.2e-05 23.1 0.2 0.00014 21.6 0.2 1.7 1 0 0 1 1 1 1 Putative peptidase (DUF1758) NIL PF09383.10 CDJ84352.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 NIL domain zf-CCHC_4 PF14392.6 CDJ84352.1 - 0.37 10.6 6.6 0.78 9.5 6.6 1.5 1 0 0 1 1 1 0 Zinc knuckle ASPRs PF17641.2 CDJ84353.1 - 0.0037 17.5 0.0 0.0045 17.2 0.0 1.1 1 0 0 1 1 1 1 Ancylostoma-associated secreted protein related ASPRs PF17641.2 CDJ84355.1 - 0.1 12.9 0.0 0.13 12.6 0.0 1.4 1 1 0 1 1 1 0 Ancylostoma-associated secreted protein related DUF202 PF02656.15 CDJ84356.1 - 4.5 7.8 9.3 3.9 8.0 4.9 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) HIG_1_N PF04588.13 CDJ84357.1 - 2.5e-14 53.2 1.7 3.9e-14 52.6 1.7 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF883 PF05957.13 CDJ84357.1 - 0.01 16.4 0.0 0.017 15.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) RNA_pol_Rpb5_N PF03871.14 CDJ84358.1 - 1.7e-35 121.4 0.3 2.8e-35 120.7 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain RNA_pol_Rpb5_C PF01191.19 CDJ84358.1 - 1.9e-34 117.3 1.3 2.6e-34 116.9 0.2 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain Mrr_cat PF04471.12 CDJ84358.1 - 0.097 12.7 0.0 0.31 11.1 0.0 1.8 2 0 0 2 2 2 0 Restriction endonuclease Microcin PF03526.13 CDJ84358.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Colicin E1 (microcin) immunity protein Med15_fungi PF05397.12 CDJ84358.1 - 0.18 12.1 3.2 1 9.6 0.1 2.5 2 1 0 2 2 2 0 Mediator complex subunit 15 BTB_2 PF02214.22 CDJ84359.1 - 5.4e-22 77.9 0.0 1.8e-21 76.3 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 CDJ84359.1 - 0.068 13.3 0.0 0.47 10.6 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain PI-PLC-X PF00388.19 CDJ84360.1 - 5.3e-05 22.8 0.0 8.5e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain CUB PF00431.20 CDJ84361.1 - 5.8e-111 364.6 1.6 6.8e-26 90.8 0.1 5.3 5 0 0 5 5 5 5 CUB domain Astacin PF01400.24 CDJ84361.1 - 8.2e-75 250.6 0.1 1.3e-74 250.0 0.1 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.15 CDJ84361.1 - 3.9e-17 62.2 20.3 3.3e-09 36.8 5.9 2.9 2 0 0 2 2 2 2 Calcium-binding EGF domain FXa_inhibition PF14670.6 CDJ84361.1 - 1.3e-16 60.6 25.9 6.3e-09 36.0 9.5 3.1 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site cEGF PF12662.7 CDJ84361.1 - 4.9e-11 42.3 8.7 8.1e-05 22.5 2.7 3.5 2 0 0 2 2 2 2 Complement Clr-like EGF-like hEGF PF12661.7 CDJ84361.1 - 1.6e-06 28.5 9.8 0.0035 17.9 1.8 3.6 3 0 0 3 3 3 2 Human growth factor-like EGF CUB_2 PF02408.20 CDJ84361.1 - 3.5e-06 26.8 4.4 0.11 12.3 0.1 4.0 4 0 0 4 4 4 2 CUB-like domain EGF PF00008.27 CDJ84361.1 - 0.00029 21.1 21.8 0.0079 16.5 3.6 3.8 3 0 0 3 3 3 2 EGF-like domain EGF_MSP1_1 PF12946.7 CDJ84361.1 - 0.0033 17.5 18.2 0.033 14.3 2.1 3.8 3 0 0 3 3 3 2 MSP1 EGF domain 1 Reprolysin_4 PF13583.6 CDJ84361.1 - 0.019 14.6 0.0 0.049 13.3 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like EGF_3 PF12947.7 CDJ84361.1 - 0.03 14.5 23.8 0.8 10.0 7.9 3.1 2 0 0 2 2 2 0 EGF domain Peptidase_M10 PF00413.24 CDJ84361.1 - 0.051 13.4 1.0 1.1 9.1 0.3 2.4 1 1 1 2 2 2 0 Matrixin BRCA2 PF00634.18 CDJ84361.1 - 0.087 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 BRCA2 repeat Cofilin_ADF PF00241.20 CDJ84362.1 - 8.6e-32 109.5 0.1 3.7e-20 71.9 0.1 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF4207 PF13904.6 CDJ84362.1 - 0.053 13.2 0.1 0.082 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) DUF229 PF02995.17 CDJ84363.1 - 5.7e-109 365.0 0.1 5.7e-109 365.0 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 CDJ84363.1 - 0.031 13.7 0.1 0.19 11.1 0.0 2.0 1 1 1 2 2 2 0 Sulfatase MtmB PF05369.12 CDJ84363.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB Pkinase_Tyr PF07714.17 CDJ84364.1 - 4.6e-63 212.9 0.0 5.5e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ84364.1 - 1.2e-30 106.8 0.0 1.8e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDJ84364.1 - 9.5e-07 28.8 0.0 2.1e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Epimerase PF01370.21 CDJ84365.1 - 1.4e-09 37.8 0.0 3.8e-07 29.8 0.0 2.2 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CDJ84365.1 - 4.8e-07 29.5 0.0 1e-06 28.4 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 CDJ84365.1 - 3e-05 23.7 0.0 6.8e-05 22.5 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 CDJ84365.1 - 0.00059 19.8 0.0 0.00094 19.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 CDJ84365.1 - 0.011 15.3 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.19 CDJ84365.1 - 0.063 12.3 0.0 0.64 9.0 0.0 1.9 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family PsbX PF06596.11 CDJ84365.1 - 0.098 12.7 2.6 0.2 11.7 2.6 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) KR PF08659.10 CDJ84365.1 - 0.19 11.6 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 KR domain zf-Tim10_DDP PF02953.15 CDJ84367.1 - 3.9e-20 71.2 1.6 4.7e-20 71.0 1.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 CDJ84367.1 - 0.087 12.5 1.8 1.3 8.7 0.5 1.9 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) EF-hand_14 PF17959.1 CDJ84367.1 - 0.14 12.5 0.2 0.14 12.5 0.2 1.3 1 1 0 1 1 1 0 EF-hand domain Coat_F PF07875.12 CDJ84367.1 - 0.36 11.1 2.1 0.84 9.9 0.4 2.0 2 0 0 2 2 2 0 Coat F domain TPR_19 PF14559.6 CDJ84368.1 - 9.5e-05 22.8 24.6 0.17 12.4 1.0 6.9 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ84368.1 - 0.0024 18.6 36.2 6 8.0 0.7 10.0 7 3 4 11 11 11 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ84368.1 - 0.076 13.2 22.4 0.36 11.1 0.1 5.8 6 1 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CDJ84368.1 - 0.08 13.1 13.1 0.086 13.0 0.1 4.6 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ84368.1 - 0.19 12.2 0.1 0.19 12.2 0.1 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ84368.1 - 0.21 11.7 18.7 2 8.6 0.1 8.2 8 1 2 10 10 10 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ84368.1 - 0.5 11.1 31.0 2.2 9.0 1.8 7.2 3 2 5 8 8 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ84368.1 - 9.1 6.4 6.7 9.4 6.4 1.2 3.6 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat FAD_binding_2 PF00890.24 CDJ84370.1 - 1.4e-89 301.1 0.5 1.6e-89 300.9 0.5 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CDJ84370.1 - 1.3e-09 38.1 4.1 6.8e-09 35.8 2.9 2.4 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CDJ84370.1 - 4.2e-09 36.3 2.8 2.6e-08 33.7 2.8 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CDJ84370.1 - 5.8e-07 29.0 1.4 1.8e-06 27.4 1.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDJ84370.1 - 1.7e-06 28.2 0.3 9.9e-06 25.7 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CDJ84370.1 - 3.7e-06 26.3 3.0 0.00028 20.1 0.2 2.8 3 0 0 3 3 3 2 Glucose inhibited division protein A HI0933_like PF03486.14 CDJ84370.1 - 4.5e-06 25.6 5.3 0.00017 20.4 0.9 2.9 3 0 0 3 3 3 2 HI0933-like protein AlaDh_PNT_C PF01262.21 CDJ84370.1 - 0.00089 18.6 0.4 0.0061 15.9 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 CDJ84370.1 - 0.0028 17.0 0.2 0.018 14.3 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CDJ84370.1 - 0.0062 16.5 0.2 1.7 8.6 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 CDJ84370.1 - 0.03 13.6 4.9 0.046 13.0 1.3 2.6 2 1 1 3 3 3 0 Thi4 family Pyr_redox PF00070.27 CDJ84370.1 - 0.031 14.8 1.1 0.1 13.2 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CDJ84370.1 - 0.035 13.4 0.7 0.076 12.3 0.6 1.5 1 1 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 CDJ84370.1 - 0.04 14.4 0.1 0.56 10.7 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 CDJ84370.1 - 0.054 12.5 1.3 0.2 10.7 0.6 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.24 CDJ84370.1 - 0.073 12.3 1.6 2.9 7.1 0.2 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase MFS_1 PF07690.16 CDJ84372.1 - 1.2e-17 63.9 23.1 3.8e-10 39.2 7.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ84372.1 - 7e-13 48.2 5.2 1.7e-06 27.2 7.0 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter CaiF_GrlA PF07180.11 CDJ84372.1 - 0.047 13.7 0.1 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 CaiF/GrlA transcriptional regulator MFS_4 PF06779.14 CDJ84372.1 - 0.047 13.0 1.4 0.061 12.6 1.4 1.1 1 0 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB ATP_synth_reg PF14960.6 CDJ84372.1 - 0.061 12.8 0.4 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 ATP synthase regulation DUF5352 PF17303.2 CDJ84373.1 - 6.4e-77 257.1 0.4 7.6e-77 256.9 0.4 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5352) DUF5352 PF17303.2 CDJ84374.1 - 3.4e-06 27.0 0.4 9.1e-06 25.6 0.0 1.7 1 1 1 2 2 2 1 Family of unknown function (DUF5352) Urocanase PF01175.18 CDJ84376.1 - 2.5e-87 292.0 0.0 3.1e-87 291.6 0.0 1.1 1 0 0 1 1 1 1 Urocanase Rossmann-like domain Urocanase_N PF17391.2 CDJ84376.1 - 9.2e-53 177.3 0.0 5e-52 174.9 0.0 2.0 2 0 0 2 2 2 1 Urocanase N-terminal domain Urocanase_C PF17392.2 CDJ84376.1 - 3.6e-08 33.1 0.1 6.5e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 Urocanase C-terminal domain GDI PF00996.18 CDJ84377.1 - 1e-219 729.5 0.0 1.1e-219 729.3 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor SH3_14 PF18343.1 CDJ84377.1 - 0.017 15.3 0.1 11 6.1 0.0 2.8 3 0 0 3 3 3 0 Dda helicase SH3 domain YodL PF14191.6 CDJ84377.1 - 0.029 15.2 0.0 2.1 9.2 0.0 3.1 3 0 0 3 3 3 0 YodL-like Methyltransf_23 PF13489.6 CDJ84378.1 - 9.8e-16 58.0 0.0 1.7e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ84378.1 - 3.8e-14 53.1 0.1 8.1e-14 52.0 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ84378.1 - 1.5e-13 51.3 0.1 4e-13 49.9 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ84378.1 - 1.2e-12 47.9 0.0 2.6e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ84378.1 - 1.8e-11 44.6 0.0 4.6e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CDJ84378.1 - 1.3e-06 28.1 0.1 2.1e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CDJ84378.1 - 1.3e-05 24.8 0.0 2.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 CDJ84378.1 - 3.7e-05 23.2 0.0 6.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 CDJ84378.1 - 5.2e-05 23.0 0.0 0.00013 21.6 0.0 1.6 2 0 0 2 2 2 1 Nodulation protein S (NodS) Complex1_LYR PF05347.15 CDJ84378.1 - 0.00013 21.9 0.0 0.00026 20.9 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Methyltransf_32 PF13679.6 CDJ84378.1 - 0.00043 20.3 0.1 0.0011 19.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain CCDC53 PF10152.9 CDJ84378.1 - 0.0021 18.5 0.0 0.003 18.0 0.0 1.3 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex AdoMet_MTase PF07757.13 CDJ84378.1 - 0.0043 17.4 0.0 0.0094 16.3 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase TehB PF03848.14 CDJ84378.1 - 0.018 14.5 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB GidB PF02527.15 CDJ84378.1 - 0.038 13.3 1.5 0.074 12.4 0.2 2.2 2 1 0 2 2 2 0 rRNA small subunit methyltransferase G MetW PF07021.12 CDJ84378.1 - 0.14 11.7 1.3 0.22 11.1 0.2 1.9 2 1 0 2 2 2 0 Methionine biosynthesis protein MetW Arf PF00025.21 CDJ84379.1 - 3.4e-46 156.9 0.2 4e-46 156.6 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CDJ84379.1 - 1.4e-20 73.5 0.0 1.7e-20 73.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ84379.1 - 1.3e-17 64.1 0.0 2e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CDJ84379.1 - 8.2e-10 38.4 0.0 9.6e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CDJ84379.1 - 1.7e-09 37.4 0.0 1.9e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CDJ84379.1 - 6.4e-09 35.4 0.4 1.8e-05 24.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 CDJ84379.1 - 1.8e-08 34.4 0.0 1.3e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CDJ84379.1 - 0.001 19.1 0.1 0.49 10.4 0.2 2.5 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 CDJ84379.1 - 0.0014 18.2 0.0 0.011 15.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain VirE PF05272.11 CDJ84379.1 - 0.0077 16.0 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Virulence-associated protein E AAA PF00004.29 CDJ84379.1 - 0.053 13.9 0.0 0.086 13.3 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CDJ84379.1 - 0.12 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 CDJ84379.1 - 0.16 11.5 1.5 0.38 10.3 0.1 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B fn3 PF00041.21 CDJ84380.1 - 3.8e-253 818.7 39.5 3.6e-17 62.5 0.1 18.7 19 0 0 19 19 17 17 Fibronectin type III domain I-set PF07679.16 CDJ84380.1 - 5.7e-222 718.6 5.5 1.6e-22 79.3 0.0 18.7 22 0 0 22 22 19 14 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ84380.1 - 1.8e-136 445.0 12.6 1.8e-15 57.3 0.0 17.3 18 0 0 18 18 16 13 Immunoglobulin domain Ig_2 PF13895.6 CDJ84380.1 - 3.2e-78 258.1 5.3 5.3e-09 36.3 0.0 14.6 14 0 0 14 14 14 11 Immunoglobulin domain Pkinase PF00069.25 CDJ84380.1 - 3e-67 226.8 0.0 4.2e-67 226.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ig PF00047.25 CDJ84380.1 - 1.2e-63 211.2 14.2 4.8e-09 36.3 0.0 13.1 13 0 0 13 13 13 9 Immunoglobulin domain V-set PF07686.17 CDJ84380.1 - 2e-38 130.9 22.2 0.0009 19.4 0.0 17.5 14 5 0 14 14 14 8 Immunoglobulin V-set domain Pkinase_Tyr PF07714.17 CDJ84380.1 - 2.2e-34 118.9 0.0 3.2e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pur_ac_phosph_N PF16656.5 CDJ84380.1 - 4.7e-18 65.6 32.8 0.41 11.2 0.0 17.8 19 1 0 19 19 16 4 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.5 CDJ84380.1 - 1.4e-12 47.6 0.0 2.4 8.4 0.0 10.1 10 0 0 10 10 10 2 Fibronectin type III domain Izumo-Ig PF16706.5 CDJ84380.1 - 6.1e-12 45.4 6.1 0.054 13.6 0.0 9.5 10 0 0 10 10 10 2 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 CDJ84380.1 - 4.2e-11 43.0 6.7 4.2 7.6 0.1 11.2 11 1 1 12 12 11 2 Natural killer cell receptor 2B4 C2-set_2 PF08205.12 CDJ84380.1 - 3.2e-10 40.0 13.8 1 9.5 0.0 9.2 9 1 1 10 10 10 4 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 CDJ84380.1 - 5.5e-09 35.9 0.2 0.31 11.1 0.0 5.7 5 1 0 5 5 5 2 C17orf99 Ig domain Ig_6 PF18452.1 CDJ84380.1 - 3.5e-06 26.5 0.1 4.2 7.0 0.0 6.8 10 0 0 10 10 7 2 Immunoglobulin domain DUF4959 PF16323.5 CDJ84380.1 - 1.5e-05 25.3 0.0 11 6.5 0.0 6.6 8 0 0 8 8 4 0 Domain of unknown function (DUF4959) Pkinase_fungal PF17667.1 CDJ84380.1 - 2.7e-05 23.1 0.0 4.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Ig_4 PF16680.5 CDJ84380.1 - 9.9e-05 22.5 7.2 3.4 8.0 0.0 6.5 7 0 0 7 7 6 1 T-cell surface glycoprotein CD3 delta chain DUF2369 PF10179.9 CDJ84380.1 - 0.00012 22.4 0.0 20 5.7 0.0 7.7 11 0 0 11 11 7 0 Uncharacterised conserved protein (DUF2369) C1-set PF07654.15 CDJ84380.1 - 0.00072 19.9 13.3 9 6.8 0.0 8.5 10 0 0 10 10 8 0 Immunoglobulin C1-set domain Kdo PF06293.14 CDJ84380.1 - 0.0019 17.6 0.1 0.0034 16.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family bMG6 PF17962.1 CDJ84380.1 - 0.0032 17.6 18.7 4.3 7.5 0.1 11.0 14 0 0 14 14 10 1 Bacterial macroglobulin domain 6 DUF11 PF01345.18 CDJ84380.1 - 0.0083 16.4 19.3 2.5 8.5 0.0 9.9 12 1 1 13 13 8 1 Domain of unknown function DUF11 Choline_kinase PF01633.20 CDJ84380.1 - 0.012 15.2 0.1 0.023 14.3 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 CDJ84380.1 - 0.031 14.2 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Egh16-like PF11327.8 CDJ84380.1 - 0.048 14.1 0.4 2.5e+02 1.9 0.0 5.4 5 1 1 7 7 5 0 Egh16-like virulence factor CRISPR_assoc PF08798.11 CDJ84380.1 - 0.11 12.6 0.0 44 4.1 0.0 4.4 4 0 0 4 4 4 0 CRISPR associated protein DAGK_acc PF00609.19 CDJ84381.1 - 3e-45 154.4 0.0 5.2e-45 153.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 CDJ84381.1 - 5.9e-27 93.8 0.0 1.4e-26 92.6 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 CDJ84381.1 - 9.2e-18 63.9 34.7 3.1e-09 36.6 15.6 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) SPO11_like PF03533.14 CDJ84381.1 - 0.0058 16.7 0.2 0.46 10.6 0.0 2.9 2 0 0 2 2 2 1 SPO11 homologue C1_2 PF03107.16 CDJ84381.1 - 0.0087 16.4 2.3 0.0087 16.4 2.3 2.6 2 0 0 2 2 2 1 C1 domain SLX9 PF15341.6 CDJ84381.1 - 0.21 12.0 3.6 0.52 10.7 3.6 1.7 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Acyl-CoA_dh_N PF02771.16 CDJ84382.1 - 2.2e-10 41.2 0.0 4.7e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 CDJ84382.1 - 0.00028 21.1 0.0 0.00077 19.7 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2096 PF09869.9 CDJ84382.1 - 0.1 12.7 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) DAGK_cat PF00781.24 CDJ84384.1 - 3.2e-27 94.6 0.0 7.8e-27 93.4 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 CDJ84384.1 - 1.6e-14 53.5 35.5 5.1e-10 39.1 13.8 2.7 1 1 1 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) SPO11_like PF03533.14 CDJ84384.1 - 0.0026 17.8 0.2 0.3 11.2 0.0 2.8 2 0 0 2 2 2 1 SPO11 homologue C1_2 PF03107.16 CDJ84384.1 - 0.0055 17.0 2.3 0.0055 17.0 2.3 2.7 2 0 0 2 2 2 1 C1 domain SLX9 PF15341.6 CDJ84384.1 - 0.61 10.5 5.8 1.6 9.1 5.9 1.7 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 HTH_Tnp_Tc3_2 PF01498.18 CDJ84385.1 - 1.2e-21 76.7 2.6 1.7e-21 76.2 0.6 2.1 2 1 0 2 2 2 1 Transposase PAX PF00292.18 CDJ84385.1 - 3.3e-09 36.7 0.3 4.4e-09 36.3 0.3 1.2 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 CDJ84385.1 - 4.1e-08 32.8 1.2 0.0002 21.0 0.0 2.5 2 1 0 2 2 2 2 Homeodomain-like domain HTH_32 PF13565.6 CDJ84385.1 - 1e-07 32.4 3.3 1.5e-07 31.9 0.5 2.2 1 1 1 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 CDJ84385.1 - 1.1e-05 25.4 0.8 0.0039 17.2 0.1 2.4 2 0 0 2 2 2 2 Winged helix-turn helix CENP-B_N PF04218.13 CDJ84385.1 - 7.6e-05 22.3 0.1 0.42 10.3 0.0 2.3 2 0 0 2 2 2 2 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 CDJ84385.1 - 0.00019 21.5 0.2 0.17 12.0 0.1 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_24 PF13412.6 CDJ84385.1 - 0.00048 19.6 2.2 1.4 8.6 0.0 3.2 2 1 1 3 3 3 2 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 CDJ84385.1 - 0.00056 19.7 2.4 0.74 9.7 0.1 2.5 2 1 0 2 2 2 2 MarR family Sigma70_r4_2 PF08281.12 CDJ84385.1 - 0.0016 18.1 0.5 0.49 10.1 0.0 2.6 2 1 0 2 2 2 1 Sigma-70, region 4 GerE PF00196.19 CDJ84385.1 - 0.0047 16.5 0.1 0.86 9.2 0.0 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family TrmB PF01978.19 CDJ84385.1 - 0.0075 16.1 0.0 0.25 11.2 0.0 2.4 2 1 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_38 PF13936.6 CDJ84385.1 - 0.0084 15.9 2.2 0.1 12.4 0.2 2.9 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_12 PF08461.10 CDJ84385.1 - 0.011 15.7 0.1 0.025 14.5 0.1 1.7 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain Sigma70_r4 PF04545.16 CDJ84385.1 - 0.017 14.7 0.8 6.8 6.3 0.1 2.9 2 1 0 2 2 2 0 Sigma-70, region 4 HTH_21 PF13276.6 CDJ84385.1 - 0.018 15.1 0.1 0.12 12.5 0.0 2.2 2 1 0 2 2 2 0 HTH-like domain HTH_11 PF08279.12 CDJ84385.1 - 0.022 14.7 2.9 0.71 9.9 0.7 3.2 2 2 0 2 2 2 0 HTH domain HTH_Crp_2 PF13545.6 CDJ84385.1 - 0.024 14.6 1.0 1.4 8.9 0.0 2.6 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain HTH_7 PF02796.15 CDJ84385.1 - 0.046 13.8 4.5 8.5 6.5 0.1 3.3 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_AsnC-type PF13404.6 CDJ84385.1 - 0.078 12.8 3.9 0.43 10.5 2.1 2.8 2 1 0 2 2 2 0 AsnC-type helix-turn-helix domain Met_10 PF02475.16 CDJ84386.1 - 5.8e-48 163.3 0.1 1.3e-47 162.1 0.0 1.6 2 0 0 2 2 2 1 Met-10+ like-protein PrmA PF06325.13 CDJ84386.1 - 0.16 11.3 0.0 0.37 10.1 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) C2 PF00168.30 CDJ84388.1 - 2.9e-07 30.7 0.0 6.7e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 C2 domain Piwi PF02171.17 CDJ84389.1 - 3.4e-63 213.7 0.0 4.2e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 Piwi domain Shisa PF13908.6 CDJ84390.1 - 0.00067 20.0 0.1 0.00067 20.0 0.1 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM52 PF14979.6 CDJ84390.1 - 0.032 14.2 0.0 0.037 14.0 0.0 1.1 1 0 0 1 1 1 0 Transmembrane 52 EphA2_TM PF14575.6 CDJ84390.1 - 0.04 14.8 0.3 0.061 14.2 0.3 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DAG1 PF05454.11 CDJ84390.1 - 0.043 13.2 0.2 0.048 13.0 0.2 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Stevor PF17410.2 CDJ84390.1 - 0.062 12.8 0.4 0.063 12.8 0.4 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4448 PF14610.6 CDJ84390.1 - 0.067 13.0 0.0 0.073 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF2207 PF09972.9 CDJ84390.1 - 0.071 11.9 0.0 0.078 11.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PAP_PilO PF06864.12 CDJ84390.1 - 0.23 10.3 0.0 0.25 10.2 0.0 1.0 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Synaptobrevin PF00957.21 CDJ84390.1 - 0.81 9.5 3.5 1.1 9.1 3.5 1.2 1 0 0 1 1 1 0 Synaptobrevin HemY_N PF07219.13 CDJ84390.1 - 2.1 8.6 6.1 16 5.7 5.6 2.0 1 1 1 2 2 2 0 HemY protein N-terminus Gal-bind_lectin PF00337.22 CDJ84391.1 - 2.1e-71 237.7 0.0 1.2e-36 125.2 0.0 2.0 2 0 0 2 2 2 2 Galactoside-binding lectin Alginate_lyase2 PF08787.11 CDJ84391.1 - 0.046 13.6 0.1 0.41 10.5 0.0 2.1 1 1 0 2 2 2 0 Alginate lyase Gal-bind_lectin PF00337.22 CDJ84392.1 - 1.1e-35 122.1 0.0 1.2e-27 96.0 0.0 2.0 2 0 0 2 2 2 2 Galactoside-binding lectin TIMP PF00965.17 CDJ84393.1 - 1.6e-18 67.1 0.0 2e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.21 CDJ84393.1 - 1.9e-09 37.3 0.0 2.3e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Trypsin PF00089.26 CDJ84395.1 - 6e-55 186.4 0.8 7.2e-55 186.2 0.8 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CDJ84395.1 - 2.9e-08 34.1 0.0 7.6e-08 32.8 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 CDJ84395.1 - 0.00087 20.2 0.1 0.0014 19.5 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain RVT_1 PF00078.27 CDJ84397.1 - 1.6e-08 34.4 0.0 1.7e-08 34.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MMACHC PF16690.5 CDJ84399.1 - 1.7e-71 240.4 0.0 1.1e-70 237.7 0.0 1.9 1 1 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family TPT PF03151.16 CDJ84400.1 - 2.2e-71 240.6 14.9 2.6e-71 240.3 14.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CDJ84400.1 - 1.1e-13 51.6 21.0 2e-07 31.2 7.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family Topoisom_bac PF01131.20 CDJ84401.1 - 2.1e-112 376.1 0.1 5.4e-112 374.8 0.0 1.8 2 0 0 2 2 2 1 DNA topoisomerase Toprim PF01751.22 CDJ84401.1 - 2.4e-18 66.2 0.9 1e-17 64.2 0.0 2.6 3 0 0 3 3 3 1 Toprim domain ArAE_2_N PF10337.9 CDJ84401.1 - 0.085 11.9 9.0 0.21 10.6 9.0 1.6 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal zf-H2C2_2 PF13465.6 CDJ84402.1 - 1.7e-13 50.3 29.6 5e-06 26.7 1.4 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 CDJ84402.1 - 2e-12 46.8 27.3 5e-06 26.7 1.2 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ84402.1 - 3.4e-10 39.9 26.8 7.1e-05 23.3 1.2 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CDJ84402.1 - 9.5e-07 28.5 9.9 2.2e-05 24.1 0.3 3.4 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 CDJ84402.1 - 4.4e-06 26.8 7.5 0.0022 18.3 0.1 3.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CDJ84402.1 - 0.00039 20.6 1.6 0.00039 20.6 1.6 3.1 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 CDJ84402.1 - 0.0034 17.2 0.7 0.016 15.0 0.4 2.3 1 1 1 2 2 2 1 GAGA factor zf-C2HE PF16278.5 CDJ84402.1 - 0.0078 16.6 6.8 0.25 11.8 0.1 3.6 2 1 1 3 3 3 1 C2HE / C2H2 / C2HC zinc-binding finger DUF3268 PF11672.8 CDJ84402.1 - 0.026 14.8 0.3 0.026 14.8 0.3 2.1 3 0 0 3 3 2 0 zinc-finger-containing domain Cys_rich_CPCC PF14206.6 CDJ84402.1 - 0.077 12.8 4.4 3.4 7.6 0.1 3.5 3 0 0 3 3 3 0 Cysteine-rich CPCC zf-C2H2_8 PF15909.5 CDJ84402.1 - 0.099 12.9 8.8 0.96 9.8 1.1 2.9 2 1 0 2 2 2 0 C2H2-type zinc ribbon Rpr2 PF04032.16 CDJ84402.1 - 0.13 12.6 1.6 0.29 11.4 0.3 2.2 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn-ribbon_8 PF09723.10 CDJ84402.1 - 0.14 12.3 12.1 0.18 11.9 0.8 3.4 3 0 0 3 3 3 0 Zinc ribbon domain zf-Mss51 PF13824.6 CDJ84402.1 - 0.22 11.7 7.1 3.3 7.9 0.2 3.0 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DZR PF12773.7 CDJ84402.1 - 0.23 11.5 8.8 0.25 11.4 2.5 3.0 2 1 1 3 3 3 0 Double zinc ribbon zf-TRAF PF02176.18 CDJ84402.1 - 0.37 11.5 12.1 1.3 9.8 0.7 3.2 3 0 0 3 3 3 0 TRAF-type zinc finger HypA PF01155.19 CDJ84402.1 - 0.88 9.6 9.8 5.1 7.2 2.6 3.1 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.5 CDJ84402.1 - 1 10.2 8.5 0.34 11.7 2.0 2.9 2 1 1 3 3 3 0 zinc-ribbon family zf_C2H2_ZHX PF18387.1 CDJ84402.1 - 1.1 9.0 15.5 1.2 8.8 0.1 3.7 2 1 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain YHS PF04945.13 CDJ84402.1 - 1.8 8.7 7.3 0.56 10.4 1.1 2.7 3 0 0 3 3 2 0 YHS domain DUF629 PF04780.12 CDJ84402.1 - 3.7 6.0 6.5 26 3.1 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF629) zf-C2H2_6 PF13912.6 CDJ84402.1 - 9.5 6.3 22.1 0.49 10.5 0.7 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger UDG PF03167.19 CDJ84403.1 - 2.1e-14 53.8 0.0 2.4e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF4507 PF14964.6 CDJ84405.1 - 7.3e-23 81.1 0.1 8.7e-23 80.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4507) FAM176 PF14851.6 CDJ84406.1 - 0.00016 21.4 0.0 0.00021 21.0 0.0 1.1 1 0 0 1 1 1 1 FAM176 family CRA PF06589.11 CDJ84406.1 - 0.0065 16.6 0.0 0.0095 16.0 0.0 1.2 1 0 0 1 1 1 1 Circumsporozoite-related antigen (CRA) DUF4834 PF16118.5 CDJ84406.1 - 0.024 15.6 0.1 0.033 15.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Zip PF02535.22 CDJ84406.1 - 0.071 12.3 0.1 0.08 12.1 0.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Glyco_hydro_25 PF01183.20 CDJ84407.1 - 0.00027 21.2 1.0 0.00035 20.8 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Leuk-A4-hydro_C PF09127.11 CDJ84407.1 - 0.017 15.2 0.1 0.037 14.1 0.0 1.6 2 0 0 2 2 2 0 Leukotriene A4 hydrolase, C-terminal Wzy_C_2 PF11846.8 CDJ84409.1 - 0.067 13.1 0.1 0.067 13.1 0.1 2.0 1 1 1 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal Tetraspanin PF00335.20 CDJ84409.1 - 3.9 7.1 13.5 0.46 10.1 8.5 1.8 1 1 0 1 1 1 0 Tetraspanin family zf-CCCH PF00642.24 CDJ84410.1 - 2.3e-21 75.1 13.0 9e-11 41.4 3.0 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ84410.1 - 1.6e-08 34.3 16.4 0.00011 22.2 5.2 2.4 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 CDJ84410.1 - 6.5e-05 23.6 7.7 0.0086 16.8 0.8 2.4 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 CDJ84410.1 - 0.00013 22.3 7.0 0.071 13.6 0.2 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 CDJ84410.1 - 0.00034 20.3 10.8 0.024 14.4 2.0 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger COG4 PF08318.12 CDJ84411.1 - 1e-78 264.8 1.3 1e-78 264.8 1.3 1.9 2 0 0 2 2 2 1 COG4 transport protein RINT1_TIP1 PF04437.13 CDJ84411.1 - 3.2e-07 29.6 1.0 5.3e-07 28.9 0.3 1.7 2 0 0 2 2 2 1 RINT-1 / TIP-1 family SR-25 PF10500.9 CDJ84411.1 - 2.3 7.8 23.6 1.7 8.2 18.3 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ORC3_N PF07034.11 CDJ84414.1 - 4.9e-13 48.9 9.7 7.8e-13 48.2 2.5 2.6 2 1 1 3 3 3 2 Origin recognition complex (ORC) subunit 3 N-terminus HTH_48 PF17906.1 CDJ84415.1 - 0.001 19.1 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase Ig_3 PF13927.6 CDJ84416.1 - 3.1e-12 46.9 0.0 6.6e-09 36.2 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 CDJ84416.1 - 1e-09 38.3 0.5 2.4e-07 30.7 0.0 3.4 2 2 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 CDJ84416.1 - 7e-08 32.7 0.0 1.9e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 CDJ84416.1 - 1.4e-07 31.4 0.0 1.6e-05 24.9 0.0 3.0 2 1 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 CDJ84416.1 - 1.7e-07 31.3 0.0 2e-05 24.7 0.0 3.1 2 2 0 2 2 2 1 Immunoglobulin domain C1-set PF07654.15 CDJ84416.1 - 0.0018 18.6 0.1 0.34 11.3 0.0 2.9 2 1 0 2 2 2 1 Immunoglobulin C1-set domain Ig_4 PF16680.5 CDJ84416.1 - 0.0057 16.9 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 CDJ84416.1 - 0.062 13.7 0.0 0.21 12.0 0.0 1.8 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 CDJ84416.1 - 0.15 12.1 0.6 1.5 8.9 0.1 2.5 3 0 0 3 3 3 0 C17orf99 Ig domain rve PF00665.26 CDJ84417.1 - 1.2e-21 77.1 0.0 3.7e-21 75.5 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ84417.1 - 3.9e-09 36.5 1.6 7.2e-09 35.6 1.6 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CDJ84417.1 - 0.027 14.3 0.2 0.063 13.1 0.0 1.8 2 0 0 2 2 2 0 Integrase core domain RE_Bsp6I PF09504.10 CDJ84417.1 - 0.077 12.6 0.0 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 Bsp6I restriction endonuclease YyzF PF14116.6 CDJ84417.1 - 0.18 11.9 0.2 25 5.0 0.0 2.5 2 0 0 2 2 2 0 YyzF-like protein RT_RNaseH_2 PF17919.1 CDJ84418.1 - 8.6e-34 115.6 0.1 2.1e-33 114.3 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ84418.1 - 1.7e-32 111.8 0.0 3.5e-32 110.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ84418.1 - 3.2e-17 62.8 0.0 1.3e-16 60.8 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CDJ84418.1 - 0.00012 22.6 0.0 0.00026 21.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ84418.1 - 0.00024 21.6 0.0 0.00054 20.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ84418.1 - 0.0012 19.1 0.0 0.0029 17.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease NAAA-beta PF15508.6 CDJ84418.1 - 0.011 16.0 0.1 7.1 7.0 0.0 3.3 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Ig_3 PF13927.6 CDJ84419.1 - 8.8e-26 90.3 0.3 3.9e-14 53.0 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 CDJ84419.1 - 9.1e-24 83.3 0.1 6.4e-13 48.6 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 CDJ84419.1 - 2e-19 69.5 0.0 5.7e-09 36.0 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 CDJ84419.1 - 1.3e-15 57.5 0.1 1.9e-06 28.1 0.0 3.0 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 CDJ84419.1 - 1.2e-07 31.9 0.1 0.00048 20.3 0.0 3.4 2 2 0 2 2 2 2 Immunoglobulin V-set domain Ig_5 PF16681.5 CDJ84419.1 - 0.00038 20.8 0.0 0.62 10.5 0.0 3.0 2 1 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 CDJ84419.1 - 0.0022 18.0 0.0 0.14 12.2 0.0 2.4 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 CDJ84419.1 - 0.0025 17.3 0.4 0.35 10.5 0.0 2.8 3 0 0 3 3 3 1 Immunoglobulin domain C1-set PF07654.15 CDJ84419.1 - 0.0046 17.3 0.0 0.11 12.9 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Ig_C17orf99 PF17736.1 CDJ84419.1 - 0.017 15.1 0.0 2.7 8.1 0.0 3.0 3 1 0 3 3 3 0 C17orf99 Ig domain Glyco_transf_92 PF01697.27 CDJ84420.1 - 9.7e-33 113.9 0.0 1.5e-32 113.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 CDJ84420.1 - 0.0025 18.3 0.0 0.0057 17.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Clat_adaptor_s PF01217.20 CDJ84421.1 - 2.8e-61 205.6 8.0 3e-61 205.5 8.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4649 PF15507.6 CDJ84421.1 - 0.012 15.5 1.2 0.016 15.2 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4649) VirB7 PF17413.2 CDJ84422.1 - 0.11 11.9 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein virB7 fn3 PF00041.21 CDJ84424.1 - 6.5e-05 23.2 0.1 0.008 16.5 0.0 2.4 2 0 0 2 2 2 2 Fibronectin type III domain V-set PF07686.17 CDJ84424.1 - 0.096 12.9 0.2 0.39 10.9 0.2 2.0 2 0 0 2 2 2 0 Immunoglobulin V-set domain C1_1 PF00130.22 CDJ84425.1 - 0.17 11.8 7.1 0.096 12.6 4.2 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 CDJ84425.1 - 0.32 11.1 5.9 1.5 9.0 5.1 2.3 1 1 1 2 2 2 0 PHD-finger zf-RING_9 PF13901.6 CDJ84425.1 - 0.37 10.8 8.2 0.8 9.6 8.2 1.6 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon PHD PF00628.29 CDJ84425.1 - 0.58 10.1 8.8 5.2 7.0 9.1 2.3 1 1 1 2 2 2 0 PHD-finger tRNA-synt_1 PF00133.22 CDJ84428.1 - 2e-143 478.8 0.0 2.8e-143 478.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CDJ84428.1 - 1.1e-17 63.9 0.0 4.4e-09 35.6 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CDJ84428.1 - 1.2e-16 61.0 0.0 2.1e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA PAC3 PF10178.9 CDJ84428.1 - 0.0052 16.9 0.0 0.017 15.3 0.0 1.9 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 tRNA-synt_1e PF01406.19 CDJ84428.1 - 0.0081 15.5 0.0 0.74 9.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain DZR PF12773.7 CDJ84428.1 - 0.052 13.6 1.0 0.17 11.9 1.0 1.8 1 0 0 1 1 1 0 Double zinc ribbon Lyase_N PF09092.11 CDJ84429.1 - 0.014 15.2 0.3 0.015 15.2 0.1 1.3 1 1 0 1 1 1 0 Lyase, N terminal FA_hydroxylase PF04116.13 CDJ84430.1 - 2.2e-14 54.0 16.4 2.2e-14 54.0 16.4 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Cyt-b5 PF00173.28 CDJ84430.1 - 7.5e-10 38.8 0.1 3.5e-09 36.7 0.0 2.1 2 1 1 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain TMEM189_B_dmain PF10520.9 CDJ84430.1 - 0.02 15.0 6.3 0.8 9.8 1.0 2.6 2 1 0 2 2 2 0 B domain of TMEM189, localisation domain Anth_synt_I_N PF04715.13 CDJ84430.1 - 0.12 12.6 0.2 0.24 11.6 0.2 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region DUF938 PF06080.12 CDJ84432.1 - 1.5e-65 220.8 0.0 1.8e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_4 PF02390.17 CDJ84432.1 - 0.00013 21.5 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.6 CDJ84432.1 - 0.033 14.0 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_M99_m PF17130.4 CDJ84432.1 - 0.076 13.0 0.0 0.43 10.5 0.0 2.2 2 1 0 2 2 2 0 beta-barrel domain of carboxypeptidase M99 Methyltransf_25 PF13649.6 CDJ84432.1 - 0.11 13.2 0.0 0.2 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Sulfotransfer_2 PF03567.14 CDJ84433.1 - 1.8e-50 172.2 1.8 2.4e-50 171.8 1.8 1.2 1 0 0 1 1 1 1 Sulfotransferase family DUF769 PF05590.11 CDJ84433.1 - 0.14 11.6 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Xylella fastidiosa protein of unknown function (DUF769) TbpB_A PF17484.2 CDJ84433.1 - 0.18 12.5 0.9 0.55 11.0 1.0 1.7 1 1 0 1 1 1 0 N-Lobe handle Tf-binding protein B YdaS_antitoxin PF15943.5 CDJ84434.1 - 0.16 11.9 1.2 2 8.3 0.4 2.8 1 1 2 3 3 3 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT zf-AD PF07776.15 CDJ84434.1 - 0.43 10.9 5.9 6.7 7.0 1.3 2.5 1 1 0 2 2 2 0 Zinc-finger associated domain (zf-AD) zf-FPG_IleRS PF06827.14 CDJ84434.1 - 0.64 9.9 3.5 5.9 6.8 0.4 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS PID PF00640.23 CDJ84437.1 - 1.7e-16 60.5 0.0 2.9e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH3_9 PF14604.6 CDJ84437.1 - 9.3e-12 44.6 0.0 1.9e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PTB PF08416.13 CDJ84437.1 - 1e-06 29.0 0.0 1.7e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH3_1 PF00018.28 CDJ84437.1 - 6.7e-06 25.6 0.0 1.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain PID_2 PF14719.6 CDJ84437.1 - 0.0073 16.2 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH3_2 PF07653.17 CDJ84437.1 - 0.081 12.6 0.0 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 Variant SH3 domain PDEase_I PF00233.19 CDJ84438.1 - 2.4e-68 230.4 2.1 6.9e-68 228.9 2.1 1.7 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Collagen PF01391.18 CDJ84440.1 - 5.8e-27 93.2 96.1 2.7e-09 36.6 35.6 4.1 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) ShK PF01549.24 CDJ84442.1 - 3.2e-05 24.3 5.0 5.3e-05 23.7 5.0 1.4 1 0 0 1 1 1 1 ShK domain-like FAT PF02259.23 CDJ84445.1 - 1.8e-75 254.3 0.0 2.2e-74 250.8 0.0 2.8 2 1 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 CDJ84445.1 - 1.8e-73 247.4 0.1 4e-73 246.3 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 CDJ84445.1 - 2.3e-44 151.2 8.5 1.3e-41 142.2 0.0 5.1 5 0 0 5 5 4 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 CDJ84445.1 - 9.8e-38 128.6 3.9 9.8e-38 128.6 3.9 4.5 4 0 0 4 4 4 1 FKBP12-rapamycin binding domain FATC PF02260.20 CDJ84445.1 - 2.1e-14 53.0 0.6 4.9e-14 51.8 0.6 1.7 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 CDJ84445.1 - 7.3e-08 32.7 16.1 0.00028 21.2 0.0 8.6 9 0 0 9 9 9 1 HEAT repeats HEAT PF02985.22 CDJ84445.1 - 4.1e-05 23.5 12.5 0.43 11.0 0.0 7.4 7 0 0 7 7 7 2 HEAT repeat IFRD PF05004.13 CDJ84445.1 - 0.00043 19.5 2.9 0.15 11.2 0.0 4.2 4 1 1 5 5 5 2 Interferon-related developmental regulator (IFRD) TPR_2 PF07719.17 CDJ84445.1 - 0.00046 20.1 6.6 2.4 8.5 0.2 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TFCD_C PF12612.8 CDJ84445.1 - 0.0039 17.0 3.6 15 5.3 0.6 5.2 3 1 1 4 4 4 0 Tubulin folding cofactor D C terminal TPR_1 PF00515.28 CDJ84445.1 - 0.0086 15.9 0.2 8.2 6.4 0.0 3.6 3 0 0 3 3 2 1 Tetratricopeptide repeat RIX1 PF08167.12 CDJ84445.1 - 0.0097 15.7 3.6 4.4 7.0 0.0 5.4 5 1 1 6 6 6 1 rRNA processing/ribosome biogenesis TPR_7 PF13176.6 CDJ84445.1 - 0.017 15.1 0.2 0.84 9.8 0.1 4.0 4 0 0 4 4 2 0 Tetratricopeptide repeat Tti2 PF10521.9 CDJ84445.1 - 0.02 14.4 3.2 0.57 9.7 0.1 4.0 3 1 1 4 4 4 0 Tti2 family ANAPC3 PF12895.7 CDJ84445.1 - 0.13 12.5 3.1 7.1 6.9 0.0 4.7 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Sec7_N PF12783.7 CDJ84445.1 - 0.2 11.6 9.1 0.3 11.0 0.0 5.2 4 1 1 5 5 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT_EZ PF13513.6 CDJ84445.1 - 0.26 11.8 22.1 0.29 11.7 0.0 8.3 11 1 0 11 11 8 0 HEAT-like repeat 7TM_GPCR_Srx PF10328.9 CDJ84447.1 - 4.9e-09 36.2 16.7 4.9e-09 36.2 16.7 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx EHN PF06441.12 CDJ84448.1 - 3e-21 75.8 0.1 5.5e-21 75.0 0.1 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 CDJ84448.1 - 1.3e-13 51.2 0.0 3.5e-13 49.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ84448.1 - 0.00035 21.3 0.0 0.00067 20.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family SNF2_N PF00176.23 CDJ84450.1 - 9.8e-91 304.1 2.2 1.5e-47 162.0 0.4 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ84450.1 - 1.9e-32 111.9 0.0 8.1e-15 55.1 0.0 3.1 2 0 0 2 2 2 2 Helicase conserved C-terminal domain HDA2-3 PF11496.8 CDJ84450.1 - 3.4e-18 65.8 3.2 7.8e-10 38.4 0.2 3.1 3 0 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 CDJ84450.1 - 4.2e-16 59.4 0.0 1.4e-07 31.7 0.0 3.4 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CDJ84450.1 - 0.00012 22.5 0.0 0.36 11.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 CDJ84450.1 - 0.00074 18.9 0.4 0.26 10.5 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ERCC3_RAD25_C PF16203.5 CDJ84450.1 - 0.0042 16.3 5.1 0.73 9.0 0.0 3.0 3 0 0 3 3 3 2 ERCC3/RAD25/XPB C-terminal helicase DEAD_2 PF06733.15 CDJ84450.1 - 0.0049 16.5 4.7 1.2 8.8 0.0 3.0 3 0 0 3 3 3 2 DEAD_2 Helicase_RecD PF05127.14 CDJ84450.1 - 0.0096 15.8 0.0 4.8 7.0 0.0 2.6 2 0 0 2 2 2 2 Helicase Hydantoinase_B PF02538.14 CDJ84450.1 - 0.019 13.4 0.3 1.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Hydantoinase B/oxoprolinase AAA_22 PF13401.6 CDJ84450.1 - 0.049 13.9 0.0 14 5.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain TK PF00265.18 CDJ84450.1 - 0.065 13.1 0.4 12 5.7 0.0 2.9 2 0 0 2 2 2 0 Thymidine kinase DnaT PF17948.1 CDJ84450.1 - 0.16 11.7 0.2 28 4.5 0.0 2.5 2 0 0 2 2 2 0 DnaT DNA-binding domain Nre_N PF04894.12 CDJ84450.1 - 0.18 11.6 0.6 9.3 6.0 0.0 2.7 3 0 0 3 3 3 0 Archaeal Nre, N-terminal BUD22 PF09073.10 CDJ84451.1 - 8.7e-05 22.0 2.4 8.7e-05 22.0 2.4 2.1 1 1 1 2 2 1 1 BUD22 Utp14 PF04615.13 CDJ84451.1 - 0.00018 20.3 21.7 0.00023 19.9 21.7 1.2 1 0 0 1 1 1 1 Utp14 protein DAG1 PF05454.11 CDJ84451.1 - 0.00051 19.5 0.2 0.00051 19.5 0.2 1.9 2 0 0 2 2 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Protocadherin PF08374.11 CDJ84451.1 - 0.0006 19.9 6.0 0.0006 19.9 6.0 1.8 2 0 0 2 2 2 1 Protocadherin Ureide_permease PF07168.11 CDJ84451.1 - 0.0013 17.6 2.9 0.0013 17.6 2.9 2.1 1 1 1 2 2 2 1 Ureide permease EphA2_TM PF14575.6 CDJ84451.1 - 0.0027 18.6 5.1 0.0027 18.6 5.1 2.5 2 1 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain RIFIN PF02009.16 CDJ84451.1 - 0.0041 17.0 12.0 0.0041 17.0 12.0 2.6 1 1 1 2 2 1 1 Rifin LRRC37AB_C PF14914.6 CDJ84451.1 - 0.0074 16.2 1.0 0.0074 16.2 1.0 2.8 2 1 1 3 3 2 1 LRRC37A/B like protein 1 C-terminal domain Shisa PF13908.6 CDJ84451.1 - 0.011 16.0 2.4 0.011 16.0 2.4 2.5 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator FAM176 PF14851.6 CDJ84451.1 - 0.015 14.9 2.7 0.015 14.9 2.7 3.4 2 1 1 3 3 2 0 FAM176 family Ycf70 PF17382.2 CDJ84451.1 - 0.021 15.2 0.3 0.041 14.3 0.2 1.5 1 1 0 1 1 1 0 Uncharacterized Ycf70-like Amnionless PF14828.6 CDJ84451.1 - 0.022 13.6 2.5 0.03 13.2 2.5 1.2 1 0 0 1 1 1 0 Amnionless HemX PF04375.14 CDJ84451.1 - 0.024 13.9 1.3 0.024 13.9 1.3 2.4 3 0 0 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase DcuA_DcuB PF03605.14 CDJ84451.1 - 0.035 13.0 3.7 0.054 12.4 3.7 1.2 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter YajC PF02699.15 CDJ84451.1 - 0.037 13.9 0.6 0.083 12.8 0.6 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit SID-1_RNA_chan PF13965.6 CDJ84451.1 - 0.038 12.4 5.9 0.031 12.7 4.5 1.5 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 GAPT PF11770.8 CDJ84451.1 - 0.13 12.2 1.6 0.47 10.3 0.3 2.2 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) DUF3139 PF11337.8 CDJ84451.1 - 0.14 12.8 3.1 0.22 12.2 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) Plasmodium_Vir PF05795.11 CDJ84451.1 - 0.16 11.4 23.6 0.051 13.0 9.5 2.1 1 1 1 2 2 2 0 Plasmodium vivax Vir protein CRA PF06589.11 CDJ84451.1 - 0.19 11.9 10.5 0.043 13.9 6.7 1.8 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) Conotoxin PF02950.17 CDJ84451.1 - 0.3 12.1 0.3 0.3 12.1 0.3 3.3 3 1 0 3 3 2 0 Conotoxin DUF572 PF04502.13 CDJ84451.1 - 0.44 10.1 22.3 0.074 12.7 17.5 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF2681 PF10883.8 CDJ84451.1 - 0.48 10.9 7.1 1.5 9.3 7.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) TMEM154 PF15102.6 CDJ84451.1 - 0.77 9.6 23.3 0.51 10.2 17.7 3.2 2 1 0 2 2 2 0 TMEM154 protein family DUF2149 PF09919.9 CDJ84451.1 - 0.92 9.8 4.4 1.5 9.1 3.5 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) RIC3 PF15361.6 CDJ84451.1 - 1.2 9.5 18.8 1.2 9.6 15.0 2.7 2 1 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 PP2C_2 PF13672.6 CDJ84451.1 - 2 8.0 11.2 3.6 7.2 11.2 1.5 1 0 0 1 1 1 0 Protein phosphatase 2C TMEM51 PF15345.6 CDJ84451.1 - 2.7 7.8 21.9 0.018 14.9 8.5 3.0 2 1 1 3 3 3 0 Transmembrane protein 51 CUB PF00431.20 CDJ84452.1 - 1.5e-30 105.8 0.0 8e-16 58.4 0.0 2.9 2 1 0 2 2 2 2 CUB domain Ldl_recept_a PF00057.18 CDJ84452.1 - 0.00046 20.4 6.4 0.00046 20.4 6.4 2.6 1 1 1 2 2 2 1 Low-density lipoprotein receptor domain class A Orthoreo_P10 PF07204.11 CDJ84452.1 - 0.053 13.5 0.2 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 EphA2_TM PF14575.6 CDJ84452.1 - 0.089 13.7 0.0 0.2 12.5 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CcmD PF04995.14 CDJ84452.1 - 0.2 11.7 0.4 0.42 10.7 0.4 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Collagen PF01391.18 CDJ84453.1 - 7.2e-22 76.9 92.5 1.3e-08 34.4 32.4 4.3 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ84453.1 - 2.1e-05 24.5 0.1 2.7e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Sulfotransfer_4 PF17784.1 CDJ84454.1 - 0.038 13.8 0.0 0.046 13.5 0.0 1.0 1 0 0 1 1 1 0 Sulfotransferase domain WD40 PF00400.32 CDJ84455.1 - 1.5e-34 117.4 12.4 5.3e-07 30.2 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ84455.1 - 1e-11 44.9 0.0 0.027 14.8 0.1 5.3 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CDJ84455.1 - 0.0095 15.3 0.0 0.21 10.9 0.0 2.4 1 1 1 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 CDJ84455.1 - 0.019 14.0 0.1 10 4.9 0.0 3.1 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleos_tra2_C PF07662.13 CDJ84456.1 - 6.8e-68 228.6 3.5 1.5e-67 227.5 3.5 1.5 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 CDJ84456.1 - 2e-18 66.7 5.4 2e-18 66.7 5.4 3.7 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 CDJ84456.1 - 0.00017 21.8 4.3 0.00017 21.8 4.3 3.2 3 1 0 3 3 3 1 Nucleoside recognition UPF0767 PF15990.5 CDJ84456.1 - 0.051 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 UPF0767 family Ras PF00071.22 CDJ84457.1 - 2e-61 206.4 1.4 2.3e-61 206.1 1.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ84457.1 - 6e-34 116.8 0.6 9.9e-34 116.1 0.6 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ84457.1 - 8.8e-14 51.3 0.2 1.1e-13 51.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CDJ84457.1 - 0.0001 21.8 0.2 0.00027 20.4 0.2 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CDJ84457.1 - 0.00018 21.6 0.0 0.0003 20.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ84457.1 - 0.00021 20.9 0.1 0.00065 19.3 0.1 1.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CDJ84457.1 - 0.0011 18.4 0.1 0.0018 17.7 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 CDJ84457.1 - 0.0012 18.4 0.1 0.87 9.1 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B TFX_C PF14601.6 CDJ84457.1 - 0.014 15.4 0.1 0.023 14.7 0.1 1.3 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term RsgA_GTPase PF03193.16 CDJ84457.1 - 0.024 14.5 0.1 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase DUF2757 PF10955.8 CDJ84457.1 - 0.055 13.7 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) G-alpha PF00503.20 CDJ84457.1 - 0.19 10.9 2.7 19 4.2 0.8 3.0 1 1 1 2 2 2 0 G-protein alpha subunit zf-C2H2 PF00096.26 CDJ84458.1 - 0.0029 18.0 4.1 0.0029 18.0 4.1 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 CDJ84458.1 - 0.019 14.7 1.4 0.041 13.6 1.4 1.6 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 CDJ84458.1 - 0.16 12.9 17.7 0.26 12.2 3.0 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CDJ84458.1 - 0.22 11.9 4.5 7.9 6.9 0.5 2.8 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) OrsD PF12013.8 CDJ84458.1 - 0.57 10.7 5.7 5.3 7.5 0.0 3.3 3 1 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D Peptidase_M24 PF00557.24 CDJ84459.1 - 3.2e-28 98.9 0.3 6.9e-28 97.8 0.3 1.7 1 1 0 1 1 1 1 Metallopeptidase family M24 UNC-93 PF05978.16 CDJ84460.1 - 2e-53 180.3 12.7 2e-53 180.3 12.7 2.6 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 CDJ84460.1 - 1.6e-16 60.2 29.6 2.8e-14 52.8 24.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sep15_SelM PF08806.11 CDJ84461.1 - 4.3e-22 78.1 0.0 9.8e-22 76.9 0.0 1.6 1 0 0 1 1 1 1 Sep15/SelM redox domain PRO8NT PF08082.11 CDJ84461.1 - 0.064 13.2 0.0 0.085 12.8 0.0 1.2 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain bZIP_2 PF07716.15 CDJ84462.1 - 1e-08 35.1 15.2 1.7e-08 34.4 15.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper EURL PF06937.11 CDJ84462.1 - 0.098 12.1 1.4 0.11 11.9 1.4 1.2 1 0 0 1 1 1 0 EURL protein tRNA-synt_1c_C PF03950.18 CDJ84464.1 - 2.4e-38 131.7 0.0 2.8e-38 131.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Bestrophin PF01062.21 CDJ84465.1 - 2.9e-97 325.6 2.4 3.9e-97 325.2 2.4 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel R3H-assoc PF13902.6 CDJ84465.1 - 0.091 13.1 3.5 0.15 12.4 3.5 1.3 1 0 0 1 1 1 0 R3H-associated N-terminal domain CBM_21 PF03370.13 CDJ84466.1 - 3.1e-27 95.0 0.6 3.1e-27 95.0 0.6 1.5 2 0 0 2 2 2 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CDJ84466.1 - 7.5e-12 45.7 1.0 1.3e-11 44.9 1.0 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Lectin_C PF00059.21 CDJ84467.1 - 6.4e-08 33.3 0.3 4.1e-07 30.7 0.0 2.6 2 0 0 2 2 2 1 Lectin C-type domain Lactamase_B PF00753.27 CDJ84471.1 - 3e-12 47.0 0.0 4.6e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF148 PF02520.17 CDJ84471.1 - 6.6e-12 45.5 1.4 7.1e-12 45.4 0.4 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF148 DUF148 PF02520.17 CDJ84472.1 - 2.3e-11 43.7 0.3 2.7e-11 43.6 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF148 Cation_ATPase_C PF00689.21 CDJ84473.1 - 1.2e-27 96.8 12.3 5.4e-24 84.9 12.3 2.5 1 1 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 CDJ84473.1 - 1.5e-05 24.9 0.2 1.5e-05 24.9 0.2 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Elongin_A PF06881.11 CDJ84473.1 - 0.053 14.0 3.9 0.11 13.0 3.9 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Pinin_SDK_memA PF04696.13 CDJ84473.1 - 0.15 12.1 11.5 0.23 11.5 11.5 1.2 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region zf-C2H2 PF00096.26 CDJ84475.1 - 1e-09 38.3 13.8 0.00013 22.2 1.1 4.2 3 1 1 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ84475.1 - 5.3e-08 32.9 18.9 8.7e-08 32.3 0.1 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDJ84475.1 - 0.0003 21.4 17.5 0.16 12.9 1.5 4.1 3 1 1 4 4 4 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CDJ84475.1 - 0.14 12.9 2.7 0.7 10.6 0.1 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 CDJ84475.1 - 0.16 12.1 9.6 0.19 11.8 2.5 2.6 1 1 1 2 2 2 0 Zinc ribbon domain zf-met PF12874.7 CDJ84475.1 - 0.34 11.4 15.0 0.5 10.8 1.3 3.8 3 1 1 4 4 4 0 Zinc-finger of C2H2 type zf-CCHC_2 PF13696.6 CDJ84475.1 - 0.93 9.4 3.3 4.4 7.2 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_11 PF16622.5 CDJ84475.1 - 3 7.7 9.1 13 5.6 1.2 3.3 2 1 1 3 3 3 0 zinc-finger C2H2-type Zf_RING PF16744.5 CDJ84475.1 - 4.9 7.3 7.5 29 4.9 0.2 2.4 1 1 1 2 2 2 0 KIAA1045 RING finger Ribosomal_L37ae PF01780.19 CDJ84475.1 - 8.7 6.5 10.4 6.1 7.0 1.7 2.6 1 1 1 2 2 2 0 Ribosomal L37ae protein family Amidohydro_1 PF01979.20 CDJ84476.1 - 2.8e-56 191.3 0.0 3.2e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CDJ84476.1 - 0.00048 19.7 2.2 0.13 11.7 0.0 2.9 2 1 0 2 2 2 2 Amidohydrolase family AP_endonuc_2 PF01261.24 CDJ84476.1 - 0.019 14.4 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF2935 PF11155.8 CDJ84476.1 - 0.096 13.0 0.4 0.17 12.2 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) LSDAT_euk PF18139.1 CDJ84477.1 - 3.3e-104 348.0 0.0 4.7e-104 347.5 0.0 1.2 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 CDJ84477.1 - 2.1e-16 59.8 0.0 5.3e-16 58.5 0.0 1.7 1 1 0 1 1 1 1 SLOG in TRPM, prokaryote Ank_2 PF12796.7 CDJ84477.1 - 3e-05 24.5 0.8 0.44 11.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) CALM_bind PF16025.5 CDJ84477.1 - 0.15 12.5 0.3 3 8.4 0.1 2.6 2 0 0 2 2 2 0 Calcium-dependent calmodulin binding Endomucin PF07010.12 CDJ84480.1 - 0.061 13.3 6.0 0.072 13.1 6.0 1.0 1 0 0 1 1 1 0 Endomucin Mucin PF01456.17 CDJ84480.1 - 0.83 9.6 21.6 1.2 9.2 21.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 CDJ84480.1 - 3.4 5.8 14.7 3.5 5.7 14.7 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Collagen PF01391.18 CDJ84481.1 - 0.00035 20.3 9.0 0.00078 19.2 9.0 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) PigN PF04987.14 CDJ84481.1 - 0.003 16.5 0.0 0.0041 16.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) SHR3_chaperone PF08229.11 CDJ84481.1 - 0.0052 15.8 0.0 0.0075 15.3 0.0 1.2 1 0 0 1 1 1 1 ER membrane protein SH3 SARAF PF06682.12 CDJ84481.1 - 0.0059 16.3 0.1 0.009 15.7 0.1 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis V_ATPase_I PF01496.19 CDJ84481.1 - 0.012 13.6 0.0 0.016 13.2 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Protocadherin PF08374.11 CDJ84481.1 - 0.012 15.6 0.1 0.017 15.1 0.1 1.2 1 0 0 1 1 1 0 Protocadherin AP3D1 PF06375.11 CDJ84481.1 - 0.015 15.6 9.6 0.025 14.8 9.6 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Connexin PF00029.19 CDJ84481.1 - 0.019 14.7 0.1 0.031 14.1 0.1 1.2 1 0 0 1 1 1 0 Connexin DUF4834 PF16118.5 CDJ84481.1 - 0.028 15.4 0.0 0.07 14.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) MAP17 PF15807.5 CDJ84481.1 - 0.031 14.5 0.1 0.058 13.6 0.1 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 EphA2_TM PF14575.6 CDJ84481.1 - 0.11 13.3 0.1 0.29 12.1 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Ac76 PF05814.11 CDJ84481.1 - 0.12 12.4 0.7 0.24 11.4 0.7 1.5 1 0 0 1 1 1 0 Orf76 (Ac76) FAM209 PF15206.6 CDJ84481.1 - 0.14 11.9 1.7 0.28 10.9 1.7 1.4 1 0 0 1 1 1 0 FAM209 family TMEM156 PF15106.6 CDJ84481.1 - 0.21 11.0 0.3 0.35 10.3 0.3 1.3 1 0 0 1 1 1 0 TMEM156 protein family DUF4672 PF15716.5 CDJ84481.1 - 7.4 6.2 7.8 14 5.3 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) V-SNARE PF05008.15 CDJ84483.1 - 0.051 14.0 0.9 0.13 12.6 0.9 1.7 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus GST_C_2 PF13410.6 CDJ84484.1 - 0.12 12.4 0.7 14 5.8 0.0 3.1 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain FUSC PF04632.12 CDJ84484.1 - 0.2 10.1 3.8 0.35 9.3 1.7 1.8 1 1 1 2 2 2 0 Fusaric acid resistance protein family Baculo_PEP_C PF04513.12 CDJ84484.1 - 0.26 11.3 1.3 7.3 6.6 0.6 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 CDJ84484.1 - 1.4 9.0 16.2 0.74 9.9 0.2 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Prominin PF05478.11 CDJ84484.1 - 3.4 5.5 11.3 0.12 10.4 4.4 1.9 2 0 0 2 2 2 0 Prominin DUF948 PF06103.11 CDJ84484.1 - 3.9 7.8 7.2 15 6.0 3.6 3.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) F_actin_bind PF08919.10 CDJ84484.1 - 6.7 6.9 7.8 7.6 6.7 0.3 3.1 2 1 1 3 3 3 0 F-actin binding Peptidase_A17 PF05380.13 CDJ84485.1 - 4.3e-37 127.6 0.5 9e-37 126.6 0.3 1.7 2 0 0 2 2 2 1 Pao retrotransposon peptidase Integrase_H2C2 PF17921.1 CDJ84485.1 - 1.1e-06 28.7 1.1 2e-06 27.8 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CDJ84485.1 - 0.052 13.8 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger DUF1758 PF05585.12 CDJ84486.1 - 0.18 11.6 0.0 0.41 10.4 0.0 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF1759 PF03564.15 CDJ84487.1 - 2.2e-23 82.9 0.8 2.2e-23 82.9 0.8 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1759) Phasin_2 PF09361.10 CDJ84487.1 - 0.3 11.4 4.8 0.78 10.0 4.8 1.6 1 0 0 1 1 1 0 Phasin protein HTH_48 PF17906.1 CDJ84488.1 - 1.1e-13 51.0 0.1 1.6e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 CDJ84488.1 - 2.1e-05 25.0 0.5 7.1e-05 23.4 0.1 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 CDJ84488.1 - 0.00033 20.8 0.0 0.00051 20.2 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_24 PF13412.6 CDJ84488.1 - 0.003 17.1 0.0 0.0065 16.0 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 CDJ84488.1 - 0.0045 16.9 0.1 0.011 15.7 0.1 1.6 1 0 0 1 1 1 1 HTH domain HTH_AsnC-type PF13404.6 CDJ84488.1 - 0.0093 15.8 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_Tnp_IS630 PF01710.16 CDJ84488.1 - 0.032 14.3 0.1 0.043 13.9 0.1 1.3 1 0 0 1 1 1 0 Transposase GerE PF00196.19 CDJ84488.1 - 0.038 13.5 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DUF488 PF04343.13 CDJ84488.1 - 0.052 14.1 0.0 0.078 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF488 Myosin_head PF00063.21 CDJ84489.1 - 3.6e-58 197.4 0.0 4.5e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) PDZ_6 PF17820.1 CDJ84489.1 - 1.7e-08 34.1 0.1 5.2e-08 32.6 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CDJ84489.1 - 3.8e-07 30.4 0.0 7.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain AAA_16 PF13191.6 CDJ84489.1 - 0.00014 22.3 0.5 0.00045 20.6 0.5 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDJ84489.1 - 0.00046 20.5 0.0 0.0014 18.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CDJ84489.1 - 0.0097 16.3 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CDJ84489.1 - 0.02 14.0 0.1 0.062 12.3 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 CDJ84489.1 - 0.02 14.6 0.2 0.062 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain PDZ_2 PF13180.6 CDJ84489.1 - 0.021 15.1 0.1 0.064 13.6 0.1 1.8 2 0 0 2 2 1 0 PDZ domain NACHT PF05729.12 CDJ84489.1 - 0.047 13.6 0.1 0.25 11.3 0.0 2.1 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 CDJ84489.1 - 0.072 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CDJ84489.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 CDJ84489.1 - 0.075 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Myosin-VI_CBD PF16521.5 CDJ84489.1 - 0.12 12.4 0.0 0.55 10.3 0.0 2.0 3 0 0 3 3 2 0 Myosin VI cargo binding domain RsgA_GTPase PF03193.16 CDJ84489.1 - 0.12 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 CDJ84489.1 - 0.14 12.0 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MeaB PF03308.16 CDJ84489.1 - 0.14 11.1 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Microtub_bd PF16796.5 CDJ84489.1 - 0.15 12.0 0.1 0.28 11.1 0.1 1.4 1 0 0 1 1 1 0 Microtubule binding cobW PF02492.19 CDJ84489.1 - 0.17 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DAP3 PF10236.9 CDJ84489.1 - 0.22 10.6 0.1 0.38 9.9 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Vps26 PF03643.15 CDJ84490.1 - 1.5e-47 161.9 0.0 1.9e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 STAR_dimer PF16544.5 CDJ84491.1 - 8.9e-26 89.2 1.0 1.8e-25 88.2 1.0 1.5 1 0 0 1 1 1 1 Homodimerisation region of STAR domain protein KH_1 PF00013.29 CDJ84491.1 - 1e-06 28.5 0.1 2.2e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 KH domain TFIIA PF03153.13 CDJ84491.1 - 8 6.3 28.2 3.5 7.5 23.7 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit START PF01852.19 CDJ84492.1 - 1.1e-17 64.2 0.0 1.4e-17 63.8 0.0 1.0 1 0 0 1 1 1 1 START domain Lipoprotein_Ltp PF07553.11 CDJ84492.1 - 0.064 13.5 0.8 0.23 11.7 0.3 2.3 2 1 0 2 2 2 0 Host cell surface-exposed lipoprotein MOLO1 PF17175.4 CDJ84494.1 - 2.5e-17 63.1 0.1 3.3e-17 62.7 0.1 1.2 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 CDJ84494.1 - 1.3e-06 28.6 0.0 1.7e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 TPM domain DUF4381 PF14316.6 CDJ84494.1 - 0.097 12.9 0.7 2 8.7 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Baculo_F PF12259.8 CDJ84494.1 - 0.11 11.0 0.4 0.59 8.6 0.2 1.8 2 0 0 2 2 2 0 Baculovirus F protein BLM10_mid PF16507.5 CDJ84495.1 - 1.6e-64 218.4 8.1 5.1e-63 213.5 8.1 2.5 1 1 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 CDJ84495.1 - 9.1e-25 86.4 0.0 8.9e-24 83.2 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) Cnd1 PF12717.7 CDJ84495.1 - 0.032 14.3 0.0 0.3 11.1 0.0 2.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DCB PF16213.5 CDJ84495.1 - 0.074 12.7 6.1 0.27 10.9 0.4 3.3 3 0 0 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 F-box_5 PF18511.1 CDJ84495.1 - 0.25 10.9 1.5 0.37 10.4 0.0 2.0 2 0 0 2 2 2 0 F-box p450 PF00067.22 CDJ84496.1 - 7.9e-92 308.4 0.0 2.4e-91 306.8 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 RE_TaqI PF09573.10 CDJ84496.1 - 0.00068 19.5 0.0 0.047 13.5 0.0 3.2 3 0 0 3 3 3 1 TaqI restriction endonuclease ACT_7 PF13840.6 CDJ84496.1 - 0.047 13.5 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 ACT domain Glyco_H_20C_C PF18088.1 CDJ84496.1 - 0.11 12.3 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 Glycoside Hydrolase 20C C-terminal domain CCDC32 PF14989.6 CDJ84500.1 - 1.3e-10 41.5 0.1 1.8e-10 41.0 0.1 1.2 1 0 0 1 1 1 1 Coiled-coil domain containing 32 WD40_like PF17005.5 CDJ84501.1 - 0.0034 16.7 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 WD40-like domain Dak1 PF02733.17 CDJ84502.1 - 1.3e-103 346.2 0.6 1.8e-103 345.7 0.6 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 CDJ84502.1 - 1.6e-40 138.8 4.4 1.6e-40 138.8 4.4 2.5 3 0 0 3 3 3 1 DAK2 domain Exo_endo_phos PF03372.23 CDJ84503.1 - 1.3e-11 44.5 0.0 1.9e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Biotin_lipoyl PF00364.22 CDJ84503.1 - 0.0013 18.5 0.8 0.11 12.4 0.7 2.8 3 0 0 3 3 3 1 Biotin-requiring enzyme Exo_endo_phos_2 PF14529.6 CDJ84503.1 - 0.022 14.6 1.0 2.3 8.1 0.0 2.7 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Neur_chan_memb PF02932.16 CDJ84504.1 - 2e-12 47.7 0.9 2.9e-12 47.2 0.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region PaRep2a PF07903.11 CDJ84504.1 - 0.011 15.6 0.1 0.4 10.5 0.1 2.2 1 1 0 1 1 1 0 PaRep2a protein HlyE PF06109.13 CDJ84504.1 - 0.049 12.9 0.0 0.16 11.2 0.0 1.7 1 1 1 2 2 2 0 Haemolysin E (HlyE) Neur_chan_LBD PF02931.23 CDJ84505.1 - 2.2e-40 138.4 2.8 2.8e-40 138.1 2.8 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain START PF01852.19 CDJ84507.1 - 2e-14 53.5 0.5 3.3e-14 52.8 0.3 1.4 1 1 0 1 1 1 1 START domain 7TM_GPCR_Srsx PF10320.9 CDJ84508.1 - 5.3e-06 26.0 0.5 6.9e-06 25.6 0.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Globin PF00042.22 CDJ84509.1 - 2.7e-07 31.1 0.0 4.6e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 Globin DSBA PF01323.20 CDJ84511.1 - 6e-39 133.8 0.0 7e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Utp13 PF08625.11 CDJ84511.1 - 0.11 12.4 0.2 0.24 11.3 0.2 1.5 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain DUF1472 PF07339.12 CDJ84511.1 - 0.13 12.8 0.0 0.38 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1472) Abhydrolase_3 PF07859.13 CDJ84512.1 - 9.9e-11 41.9 0.7 2.1e-06 27.7 0.2 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CDJ84512.1 - 7.4e-06 25.6 0.0 3.3e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CDJ84512.1 - 0.00011 21.5 0.1 0.00017 20.9 0.1 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 CDJ84512.1 - 0.00012 21.7 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 CDJ84512.1 - 0.00047 20.8 0.0 0.0034 18.0 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 CDJ84512.1 - 0.0055 16.2 0.0 0.0099 15.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3530 PF12048.8 CDJ84512.1 - 0.015 14.7 0.7 0.022 14.2 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) PGAP1 PF07819.13 CDJ84512.1 - 0.015 15.0 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase2 PF12740.7 CDJ84512.1 - 0.022 13.7 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2974 PF11187.8 CDJ84512.1 - 0.043 13.4 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 CDJ84512.1 - 0.06 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.20 CDJ84512.1 - 0.077 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain DLH PF01738.18 CDJ84512.1 - 0.09 12.3 0.0 0.19 11.3 0.0 1.4 1 1 0 1 1 1 0 Dienelactone hydrolase family DP PF08781.10 CDJ84513.1 - 1.1e-46 158.2 0.0 2e-46 157.3 0.0 1.5 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.20 CDJ84513.1 - 1.6e-22 79.3 0.4 3.1e-22 78.4 0.4 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain RNase_P_p30 PF01876.16 CDJ84514.1 - 3.7e-35 121.3 0.0 2.5e-33 115.4 0.0 2.2 1 1 0 1 1 1 1 RNase P subunit p30 Apolipoprotein PF01442.18 CDJ84516.1 - 1.1e-06 28.7 20.0 0.0028 17.5 1.1 3.6 2 1 0 3 3 3 3 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 CDJ84516.1 - 0.0028 17.8 4.4 15 5.7 0.0 5.0 3 3 2 5 5 5 2 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 CDJ84516.1 - 8.6 7.0 63.2 0.9 10.2 2.7 7.7 1 1 7 8 8 8 0 Bacterial protein of unknown function (DUF883) Hormone_recep PF00104.30 CDJ84517.1 - 7.6e-14 51.8 0.7 1.2e-13 51.1 0.7 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor U5_2-snRNA_bdg PF10597.9 CDJ84517.1 - 0.044 13.8 0.3 0.13 12.4 0.1 1.7 1 1 1 2 2 2 0 U5-snRNA binding site 2 of PrP8 Hormone_recep PF00104.30 CDJ84518.1 - 0.017 14.7 0.5 0.054 13.1 0.1 1.9 2 1 1 3 3 3 0 Ligand-binding domain of nuclear hormone receptor Frag1 PF10277.9 CDJ84519.1 - 5.5e-31 107.8 17.3 6.9e-31 107.5 17.3 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family BORA_N PF15280.6 CDJ84520.1 - 5.8e-38 130.8 3.0 1e-37 130.0 3.0 1.4 1 0 0 1 1 1 1 Protein aurora borealis N-terminus Trm112p PF03966.16 CDJ84521.1 - 2.2e-13 50.5 0.0 3.1e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Trm112p-like protein S1-like PF14444.6 CDJ84521.1 - 0.16 11.9 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 S1-like ELO PF01151.18 CDJ84522.1 - 1.8e-67 227.5 18.1 2.1e-67 227.3 18.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Asp PF00026.23 CDJ84523.1 - 6.7e-88 295.1 1.6 8e-88 294.9 1.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ84523.1 - 1.5e-11 44.9 6.6 2.2e-10 41.1 6.2 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ84523.1 - 0.00013 21.8 0.1 0.0018 18.1 0.0 2.6 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CDJ84523.1 - 0.0031 18.1 0.0 0.67 10.6 0.0 3.0 3 0 0 3 3 3 1 Aspartyl protease Pro_isomerase PF00160.21 CDJ84524.1 - 9.9e-50 168.9 0.2 1.2e-49 168.6 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cyclin_C_2 PF16899.5 CDJ84525.1 - 1e-20 74.1 0.0 5.4e-19 68.5 0.0 2.3 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 CDJ84525.1 - 1.3e-07 31.4 0.0 2.9e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CDJ84525.1 - 0.00035 20.6 0.0 0.01 15.9 0.0 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF3106 PF11304.8 CDJ84525.1 - 0.029 14.8 3.8 0.031 14.7 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) Apt1 PF10351.9 CDJ84526.1 - 1.4e-93 314.4 4.5 2.4e-92 310.3 4.5 2.2 1 1 0 1 1 1 1 Golgi-body localisation protein domain Zip PF02535.22 CDJ84526.1 - 3.2e-35 121.9 11.6 2.1e-22 79.8 2.7 2.2 1 1 1 2 2 2 2 ZIP Zinc transporter Fmp27_GFWDK PF10347.9 CDJ84526.1 - 3e-26 92.4 0.0 7.3e-26 91.1 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 CDJ84526.1 - 4.2e-05 23.5 1.1 0.00042 20.3 1.1 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF2405) DUF2509 PF10713.9 CDJ84526.1 - 0.12 12.5 2.7 1.2 9.2 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2509) Guanylate_kin PF00625.21 CDJ84527.1 - 2.3e-59 200.2 0.0 2.7e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 CDJ84527.1 - 6.9e-05 23.4 0.0 0.00013 22.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ84527.1 - 0.00033 21.1 0.2 0.0011 19.4 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CDJ84527.1 - 0.0025 18.0 0.4 0.018 15.2 0.4 2.0 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CDJ84527.1 - 0.0031 18.0 0.6 0.14 12.7 0.6 2.2 1 1 0 1 1 1 1 ABC transporter Rad17 PF03215.15 CDJ84527.1 - 0.014 15.4 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 CDJ84527.1 - 0.015 15.6 0.4 0.1 12.9 0.0 2.3 3 1 0 3 3 3 0 AAA domain AAA_29 PF13555.6 CDJ84527.1 - 0.048 13.4 0.1 0.093 12.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 CDJ84527.1 - 0.078 13.5 0.4 1.9 8.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CDJ84527.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 CDJ84527.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CDJ84527.1 - 0.17 12.3 0.0 0.37 11.2 0.0 1.7 1 1 0 1 1 1 0 RNA helicase Exo_endo_phos_2 PF14529.6 CDJ84528.1 - 1.4e-05 24.9 0.2 2.9e-05 23.9 0.1 1.7 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Ribosomal_L29 PF00831.23 CDJ84528.1 - 0.58 10.2 3.0 0.97 9.5 0.6 2.4 1 1 1 2 2 2 0 Ribosomal L29 protein RrnaAD PF00398.20 CDJ84529.1 - 1e-36 126.4 0.0 1.2e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Helitron_like_N PF14214.6 CDJ84530.1 - 1.3e-39 136.4 0.0 1.9e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.13 CDJ84530.1 - 0.23 10.5 0.7 0.35 9.9 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage replication gene A protein (GPA) Homeodomain PF00046.29 CDJ84532.1 - 1.8e-22 78.9 5.8 3e-22 78.2 5.8 1.4 1 0 0 1 1 1 1 Homeodomain Filo_glycop PF01611.16 CDJ84532.1 - 0.011 14.7 0.5 0.013 14.4 0.5 1.1 1 0 0 1 1 1 0 Filovirus glycoprotein Terminase_5 PF06056.12 CDJ84532.1 - 0.044 13.7 0.3 0.088 12.7 0.3 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Homeobox_KN PF05920.11 CDJ84532.1 - 0.085 12.8 1.2 0.085 12.8 1.2 3.0 3 1 0 3 3 3 0 Homeobox KN domain AI-2E_transport PF01594.16 CDJ84533.1 - 0.0052 16.0 30.3 0.021 14.0 18.5 3.6 3 0 0 3 3 3 3 AI-2E family transporter AI-2E_transport PF01594.16 CDJ84534.1 - 0.1 11.7 29.5 0.46 9.6 20.6 2.3 2 1 0 2 2 2 0 AI-2E family transporter Sec7 PF01369.20 CDJ84535.1 - 4.1e-49 166.7 0.2 5.8e-49 166.2 0.2 1.2 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.5 CDJ84535.1 - 6e-47 159.1 0.1 1.1e-46 158.2 0.1 1.5 1 0 0 1 1 1 1 PH domain IQ PF00612.27 CDJ84535.1 - 0.35 10.8 2.1 1.1 9.2 2.1 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif EF-hand_1 PF00036.32 CDJ84536.1 - 2.1e-28 95.7 10.6 6e-10 38.0 0.7 3.2 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 CDJ84536.1 - 2.1e-21 75.5 14.0 7.2e-09 35.4 3.1 3.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 CDJ84536.1 - 3e-21 75.6 5.5 9.4e-15 54.8 2.8 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ84536.1 - 4.8e-17 60.4 2.4 1.1e-07 31.2 0.2 3.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 CDJ84536.1 - 1.8e-13 49.3 6.1 3.9e-06 26.1 0.4 3.2 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 CDJ84536.1 - 2.7e-08 33.7 2.7 0.00081 19.3 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CDJ84536.1 - 3e-07 30.6 0.2 1.8e-05 24.9 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.10 CDJ84536.1 - 0.0041 17.2 0.8 0.006 16.7 0.8 1.3 1 0 0 1 1 1 1 Ca2+ insensitive EF hand DUF1103 PF06513.11 CDJ84536.1 - 0.0048 16.5 0.5 0.0068 16.1 0.5 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) SPARC_Ca_bdg PF10591.9 CDJ84536.1 - 0.018 15.4 0.5 0.12 12.7 0.2 1.9 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 CDJ84536.1 - 0.056 13.6 0.3 2.4 8.4 0.2 2.6 1 1 1 2 2 2 0 Dockerin type I domain EF-hand_11 PF08976.11 CDJ84536.1 - 0.067 14.1 0.1 0.18 12.7 0.1 1.6 1 1 1 2 2 2 0 EF-hand domain UPF0154 PF03672.13 CDJ84536.1 - 0.071 13.2 2.9 0.073 13.1 0.2 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0154) ASPRs PF17641.2 CDJ84538.1 - 0.043 14.1 0.0 0.046 14.0 0.0 1.1 1 0 0 1 1 1 0 Ancylostoma-associated secreted protein related CAP PF00188.26 CDJ84540.1 - 4.5e-09 37.2 0.4 7.1e-09 36.6 0.4 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family p450 PF00067.22 CDJ84541.1 - 1.3e-106 357.1 0.0 1.5e-106 357.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Kunitz_BPTI PF00014.23 CDJ84543.1 - 4.3e-161 523.2 150.2 6.7e-18 64.7 5.0 11.4 11 0 0 11 11 11 11 Kunitz/Bovine pancreatic trypsin inhibitor domain Lustrin_cystein PF14625.6 CDJ84543.1 - 1.5e-14 54.0 77.7 9.5e-07 29.1 4.9 6.5 6 0 0 6 6 6 4 Lustrin, cysteine-rich repeated domain Thyroglobulin_1 PF00086.18 CDJ84543.1 - 2.3e-14 52.8 2.0 7.4e-14 51.2 2.0 1.9 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat ABC_membrane PF00664.23 CDJ84544.2 - 1.3e-53 182.4 26.6 8.8e-33 114.1 9.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ84544.2 - 2.1e-35 122.2 0.0 3.7e-21 76.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CDJ84544.2 - 1.8e-05 24.3 0.0 0.35 10.3 0.0 3.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CDJ84544.2 - 2.6e-05 24.2 0.4 0.14 11.9 0.0 4.0 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CDJ84544.2 - 0.0015 18.5 0.0 0.0036 17.2 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 CDJ84544.2 - 0.0039 17.3 0.3 0.59 10.2 0.1 2.5 2 0 0 2 2 2 1 Dynamin family SbcCD_C PF13558.6 CDJ84544.2 - 0.024 14.8 0.0 5.6 7.3 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 CDJ84544.2 - 0.092 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain FixQ PF05545.11 CDJ84544.2 - 0.2 11.7 1.5 0.8 9.7 1.5 2.1 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DEADboxA PF12343.8 CDJ84545.1 - 0.00037 21.0 1.1 0.00078 19.9 1.1 1.5 1 0 0 1 1 1 1 Cold shock protein DEAD box A Pkinase PF00069.25 CDJ84546.1 - 8.1e-26 90.9 0.0 1e-25 90.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ84546.1 - 2.5e-13 49.9 0.0 3e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ84546.1 - 3.7e-10 39.1 0.0 3.7e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 CDJ84546.1 - 0.031 13.2 0.1 0.046 12.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 CDJ84546.1 - 0.097 12.6 0.1 1.2 9.1 0.2 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family C2 PF00168.30 CDJ84549.1 - 4.3e-56 187.6 0.1 1.9e-26 92.3 0.0 3.3 3 0 0 3 3 3 3 C2 domain SMP_LBD PF17047.5 CDJ84549.1 - 1.3e-25 89.9 0.0 2.1e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain Arrestin_N PF00339.29 CDJ84550.1 - 1.2e-39 135.7 0.1 3.5e-39 134.2 0.1 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CDJ84550.1 - 2e-17 63.9 0.6 6.6e-13 49.3 0.3 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Spo0M PF07070.11 CDJ84550.1 - 0.0076 15.8 0.0 0.03 13.8 0.0 1.9 2 0 0 2 2 2 1 SpoOM protein Vps26 PF03643.15 CDJ84550.1 - 0.014 14.4 0.0 0.043 12.8 0.0 1.7 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 26 Rgp1 PF08737.10 CDJ84550.1 - 0.027 13.7 0.1 0.5 9.5 0.0 2.3 2 0 0 2 2 2 0 Rgp1 DUF4133 PF13571.6 CDJ84552.1 - 0.35 11.2 5.4 0.2 12.0 3.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4133) UPF0016 PF01169.19 CDJ84553.1 - 1.8e-44 149.9 20.4 5.1e-22 78.0 7.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 CDJ84553.1 - 0.062 13.1 10.2 2.6 7.8 10.2 2.5 1 1 0 1 1 1 0 Putative manganese efflux pump JmjC PF02373.22 CDJ84558.1 - 2.3e-29 102.1 0.2 9e-29 100.2 0.2 2.1 1 0 0 1 1 1 1 JmjC domain, hydroxylase TPR_1 PF00515.28 CDJ84558.1 - 8.1e-27 91.9 11.5 8.4e-07 28.6 0.0 6.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ84558.1 - 1e-18 65.9 14.9 0.0026 17.7 0.0 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ84558.1 - 6.3e-15 55.6 3.7 7e-06 26.6 0.3 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ84558.1 - 2.1e-12 46.5 8.8 0.031 14.0 0.1 5.8 4 2 1 5 5 5 4 TPR repeat TPR_8 PF13181.6 CDJ84558.1 - 2e-11 43.2 2.3 0.56 10.6 0.0 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ84558.1 - 2.8e-11 43.5 12.3 0.031 14.6 0.1 5.8 2 1 4 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ84558.1 - 9.6e-10 38.2 4.7 0.026 14.9 0.0 6.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ84558.1 - 2.9e-08 34.1 1.4 0.47 11.0 0.0 4.5 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ84558.1 - 6e-07 29.7 9.8 2.5 8.9 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ84558.1 - 8.4e-07 28.6 3.7 0.0049 16.8 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ84558.1 - 3.9e-06 26.9 0.1 0.026 14.7 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ84558.1 - 2e-05 25.0 7.1 3.6 8.7 0.3 6.5 4 2 3 7 7 7 1 Tetratricopeptide repeat Aida_N PF08910.10 CDJ84558.1 - 0.0012 19.3 0.2 0.0069 16.8 0.2 2.4 2 0 0 2 2 1 1 Aida N-terminus Spectrin_like PF18373.1 CDJ84558.1 - 0.0041 17.1 0.6 0.0041 17.1 0.6 2.4 2 0 0 2 2 2 1 Spectrin like domain TPR_MalT PF17874.1 CDJ84558.1 - 0.019 14.3 1.2 0.16 11.3 0.1 2.7 3 1 0 3 3 3 0 MalT-like TPR region RPN7 PF10602.9 CDJ84558.1 - 0.025 14.3 0.0 0.56 9.9 0.0 3.1 2 1 1 3 3 3 0 26S proteasome subunit RPN7 DUF3422 PF11902.8 CDJ84558.1 - 0.88 8.6 6.0 0.14 11.3 2.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3422) TPR_15 PF13429.6 CDJ84558.1 - 0.93 8.6 7.6 0.8 8.9 2.5 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat DREV PF05219.12 CDJ84559.1 - 2.4e-86 289.1 0.0 2.8e-86 288.9 0.0 1.0 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.6 CDJ84559.1 - 6.3e-10 39.1 0.0 1.1e-09 38.4 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ84559.1 - 7.6e-05 23.3 0.0 0.00017 22.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ84559.1 - 0.0002 21.9 0.0 0.0012 19.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ84559.1 - 0.0013 18.6 0.0 0.016 15.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ84559.1 - 0.0038 17.9 0.0 0.0086 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 CDJ84559.1 - 0.023 13.7 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Nuc_deoxyri_tr2 PF15891.5 CDJ84561.1 - 1.8e-16 60.4 0.1 5.7e-16 58.8 0.0 1.8 2 0 0 2 2 2 1 Nucleoside 2-deoxyribosyltransferase like DUF3077 PF11275.8 CDJ84562.1 - 0.14 12.4 0.2 0.24 11.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3077) DUF3408 PF11888.8 CDJ84562.1 - 0.17 12.0 0.0 0.2 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Innexin PF00876.18 CDJ84563.1 - 2.9e-91 306.4 15.5 3.3e-91 306.2 15.5 1.0 1 0 0 1 1 1 1 Innexin Innexin PF00876.18 CDJ84564.1 - 4.3e-102 342.0 6.3 5.1e-102 341.8 6.3 1.0 1 0 0 1 1 1 1 Innexin Innexin PF00876.18 CDJ84565.1 - 2.1e-91 306.8 8.6 3.2e-91 306.2 8.6 1.2 1 1 0 1 1 1 1 Innexin DUF2973 PF11189.8 CDJ84565.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) RINGv PF12906.7 CDJ84566.1 - 2.6e-14 53.1 9.5 5.3e-14 52.1 9.5 1.6 1 0 0 1 1 1 1 RING-variant domain TAS2R PF05296.13 CDJ84566.1 - 0.015 14.4 3.7 0.02 14.1 3.7 1.1 1 0 0 1 1 1 0 Taste receptor protein (TAS2R) DUF3273 PF11677.8 CDJ84566.1 - 0.058 12.7 1.2 0.084 12.2 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3273) zf-RING_2 PF13639.6 CDJ84566.1 - 0.3 11.4 10.1 0.99 9.8 10.1 2.0 1 0 0 1 1 1 0 Ring finger domain DUF1758 PF05585.12 CDJ84567.1 - 1.5e-09 37.8 1.1 2.2e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 Putative peptidase (DUF1758) zf-CCHC PF00098.23 CDJ84567.1 - 8.3e-05 22.5 20.2 0.0019 18.2 1.1 3.6 3 0 0 3 3 3 2 Zinc knuckle Asp_protease_2 PF13650.6 CDJ84567.1 - 0.0012 19.5 0.0 0.0029 18.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ84567.1 - 0.0029 18.1 0.0 0.0086 16.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zinc_ribbon_2 PF13240.6 CDJ84567.1 - 0.21 11.4 1.9 23 4.9 0.1 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 CDJ84567.1 - 0.86 9.1 4.0 8.3 6.0 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain IBR PF01485.21 CDJ84567.1 - 5.1 7.4 15.8 0.91 9.8 3.0 2.8 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Neur_chan_LBD PF02931.23 CDJ84568.1 - 8.5e-47 159.4 0.1 1.3e-46 158.8 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ84568.1 - 1.2e-26 94.3 2.0 1.9e-26 93.6 2.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Glyco_hydro_35 PF01301.19 CDJ84569.1 - 0.16 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Pkinase PF00069.25 CDJ84573.1 - 3.5e-72 243.0 0.0 5e-72 242.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ84573.1 - 5.5e-45 153.7 0.2 3.4e-44 151.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 CDJ84573.1 - 1e-23 83.4 0.0 3.7e-23 81.7 0.0 2.0 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 CDJ84573.1 - 4.8e-06 26.1 0.1 7.4e-05 22.2 0.1 2.2 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CDJ84573.1 - 1.7e-05 23.8 0.0 2.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDJ84573.1 - 0.0035 16.7 0.0 0.0072 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DSHCT PF08148.12 CDJ84573.1 - 0.025 14.2 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain APH PF01636.23 CDJ84573.1 - 0.12 12.2 0.1 0.85 9.5 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 CDJ84573.1 - 0.17 11.5 0.2 0.36 10.4 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Peptidase_C1 PF00112.23 CDJ84574.1 - 3.1e-43 148.4 13.9 7.6e-42 143.8 13.9 2.1 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ84574.1 - 0.24 10.1 3.1 0.49 9.1 0.3 2.1 2 0 0 2 2 2 0 Peptidase C1-like family NT-C2 PF10358.9 CDJ84575.1 - 3.1e-19 69.1 0.0 4.3e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF2475 PF10629.9 CDJ84576.1 - 0.00068 19.8 2.4 0.36 11.1 0.4 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF2475) Lustrin_cystein PF14625.6 CDJ84577.1 - 2.4e-53 178.3 223.3 2.8e-08 34.0 7.2 15.8 14 1 0 14 14 14 13 Lustrin, cysteine-rich repeated domain Kunitz_BPTI PF00014.23 CDJ84577.1 - 4.7e-36 122.8 37.0 1.8e-15 56.9 5.4 4.9 4 0 0 4 4 4 3 Kunitz/Bovine pancreatic trypsin inhibitor domain EB PF01683.18 CDJ84577.1 - 4.6e-09 36.4 16.6 2.8e-08 33.9 5.8 12.6 9 4 2 11 11 11 2 EB module Apis_Csd PF11671.8 CDJ84577.1 - 0.19 11.7 3.8 0.4 10.7 3.8 1.4 1 0 0 1 1 1 0 Complementary sex determiner protein Ald_Xan_dh_C2 PF02738.18 CDJ84579.1 - 4.7e-135 451.2 0.7 6.2e-135 450.8 0.7 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 CDJ84579.1 - 1.3e-29 102.7 0.0 2.9e-29 101.6 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Ald_Xan_dh_C2 PF02738.18 CDJ84580.1 - 2.1e-147 491.9 0.0 2.9e-147 491.4 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Fer2_2 PF01799.20 CDJ84580.1 - 3.2e-29 100.8 0.1 1.1e-28 99.0 0.1 2.0 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.22 CDJ84580.1 - 4.2e-24 85.0 0.0 9.9e-24 83.8 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.27 CDJ84580.1 - 3.5e-07 30.1 0.3 9.7e-07 28.7 0.3 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mucin PF01456.17 CDJ84581.1 - 0.057 13.4 0.0 0.057 13.4 0.0 2.7 3 0 0 3 3 3 0 Mucin-like glycoprotein DUF2062 PF09835.9 CDJ84581.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CDC45 PF02724.14 CDJ84582.1 - 8.2 4.6 5.9 11 4.2 5.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Beta_helix PF13229.6 CDJ84583.1 - 0.001 18.9 0.1 0.0016 18.3 0.1 1.3 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 CDJ84583.1 - 0.018 14.3 0.3 0.026 13.8 0.3 1.2 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Toxin-deaminase PF14424.6 CDJ84584.1 - 0.024 14.7 0.1 0.03 14.4 0.1 1.1 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases MRP-L28 PF09812.9 CDJ84584.1 - 0.15 12.2 2.3 0.2 11.8 2.3 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 Rad50_zn_hook PF04423.14 CDJ84584.1 - 0.19 11.6 4.2 0.11 12.3 1.3 2.2 1 1 2 3 3 3 0 Rad50 zinc hook motif DUF3490 PF11995.8 CDJ84584.1 - 0.19 11.5 3.1 0.26 11.1 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) DUF1712 PF08217.11 CDJ84585.1 - 9.9e-30 103.6 0.5 4.8e-22 78.2 0.5 3.0 2 2 1 3 3 3 2 Fungal domain of unknown function (DUF1712) DUF4372 PF14294.6 CDJ84585.1 - 0.062 13.5 0.1 7 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4372) zf-C3HC4_2 PF13923.6 CDJ84587.1 - 8.9e-13 47.9 10.0 1.9e-12 46.8 10.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ84587.1 - 1.4e-09 37.7 10.2 2.7e-09 36.7 10.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ84587.1 - 3e-08 33.8 8.7 7e-08 32.7 8.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDJ84587.1 - 2e-06 27.6 6.9 3.5e-06 26.8 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ84587.1 - 5.6e-06 26.2 9.1 1.1e-05 25.3 9.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDJ84587.1 - 6.5e-06 26.1 8.7 1.5e-05 24.9 8.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDJ84587.1 - 0.00012 22.2 7.9 0.00028 21.0 7.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 CDJ84587.1 - 0.00022 21.0 3.1 0.00062 19.5 3.1 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 CDJ84587.1 - 0.0035 17.1 6.5 0.0087 15.8 6.5 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 CDJ84587.1 - 0.0085 16.4 7.8 0.04 14.2 7.8 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 CDJ84587.1 - 0.013 15.3 3.3 0.027 14.3 3.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_5 PF17121.5 CDJ84587.1 - 0.061 13.2 3.7 0.13 12.1 3.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDJ84587.1 - 0.089 12.7 8.8 2.4 8.1 9.0 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 RAWUL PF16207.5 CDJ84587.1 - 0.11 13.2 0.0 0.21 12.3 0.0 1.5 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-RING_10 PF16685.5 CDJ84587.1 - 0.15 12.2 6.6 0.35 11.0 6.6 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 U-box PF04564.15 CDJ84587.1 - 2.6 8.3 5.5 4 7.7 0.7 3.3 3 1 1 4 4 3 0 U-box domain Nop14 PF04147.12 CDJ84587.1 - 3.8 5.6 15.5 5.4 5.1 15.5 1.1 1 0 0 1 1 1 0 Nop14-like family zf-C4_Topoisom PF01396.19 CDJ84587.1 - 4.9 7.0 6.3 0.5 10.2 0.9 2.1 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-RING-like PF08746.11 CDJ84587.1 - 5 7.5 6.7 10 6.5 6.7 1.5 1 0 0 1 1 1 0 RING-like domain PIP5K PF01504.18 CDJ84588.1 - 7.4e-44 150.0 3.3 1.5e-37 129.4 2.1 2.4 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 CDJ84588.1 - 2e-18 66.3 0.0 3.1e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 CDJ84588.1 - 5.9e-17 61.6 9.7 5.9e-17 61.6 9.7 2.3 2 0 0 2 2 2 1 FYVE zinc finger TPT PF03151.16 CDJ84589.1 - 1e-16 61.2 10.0 1.2e-16 61.0 10.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CDJ84589.1 - 6.1e-07 29.7 24.8 0.00035 20.8 3.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CDJ84589.1 - 0.00079 18.7 8.6 0.002 17.4 8.6 1.8 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 CDJ84589.1 - 0.0028 17.0 9.3 0.013 14.7 9.3 1.9 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport DUF202 PF02656.15 CDJ84589.1 - 6.8 7.2 8.1 26 5.3 0.3 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF202) ASC PF00858.24 CDJ84590.1 - 1.5e-91 307.6 7.8 1.8e-91 307.3 7.8 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Peptidase_M41 PF01434.18 CDJ84591.1 - 6.7e-68 228.3 0.0 1.2e-67 227.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CDJ84591.1 - 1.7e-44 151.5 0.0 4.4e-44 150.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ84591.1 - 4.9e-14 51.9 0.1 1.4e-13 50.4 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 CDJ84591.1 - 6.8e-08 32.8 0.0 2.2e-07 31.2 0.0 2.0 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 CDJ84591.1 - 9.6e-05 22.4 0.0 0.00085 19.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CDJ84591.1 - 0.0013 18.9 0.1 0.0057 16.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CDJ84591.1 - 0.0014 18.4 0.0 0.0058 16.4 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CDJ84591.1 - 0.0018 18.5 0.0 0.09 13.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ84591.1 - 0.0036 17.7 0.0 0.16 12.4 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 CDJ84591.1 - 0.0061 15.8 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 CDJ84591.1 - 0.028 14.2 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 CDJ84591.1 - 0.042 14.4 0.0 0.66 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CDJ84591.1 - 0.044 14.2 0.4 0.1 13.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain EF-hand_like PF09279.11 CDJ84591.1 - 0.047 14.2 0.2 1.5 9.3 0.0 2.5 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like APOC4 PF15119.6 CDJ84591.1 - 0.079 13.2 0.1 4.5 7.6 0.0 2.4 2 0 0 2 2 2 0 Apolipoprotein C4 Mg_chelatase PF01078.21 CDJ84591.1 - 0.13 11.6 0.1 0.28 10.6 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 CDJ84591.1 - 0.18 12.1 0.9 0.34 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CDJ84591.1 - 0.34 10.8 1.1 15 5.4 0.2 3.2 4 0 0 4 4 4 0 NACHT domain RNA_pol_3_Rpc31 PF11705.8 CDJ84592.1 - 3.1e-21 76.7 2.6 4.1e-21 76.3 2.6 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 XPG_N PF00752.17 CDJ84593.1 - 1e-33 115.8 0.0 2.2e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CDJ84593.1 - 5.8e-29 100.3 0.1 1.3e-28 99.1 0.1 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 CDJ84593.1 - 1.1e-07 32.3 0.0 4.1e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 CDJ84593.1 - 0.026 15.1 0.0 0.093 13.4 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain 5_3_exonuc_N PF02739.16 CDJ84593.1 - 0.036 14.0 0.0 0.12 12.3 0.0 1.8 1 1 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain HHH_2 PF12826.7 CDJ84593.1 - 0.096 12.8 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif TolA_bind_tri PF16331.5 CDJ84594.1 - 0.017 15.2 2.7 0.017 15.2 2.7 7.3 7 2 1 8 8 8 0 TolA binding protein trimerisation YbjQ_1 PF01906.17 CDJ84594.1 - 0.5 11.0 2.6 1.3 9.7 0.5 2.9 2 1 1 3 3 3 0 Putative heavy-metal-binding AAA_lid_10 PF17872.1 CDJ84594.1 - 6 7.1 11.7 0.46 10.6 0.6 4.0 3 1 1 4 4 4 0 AAA lid domain Polyoma_coat PF00718.20 CDJ84595.1 - 0.042 13.2 0.0 0.046 13.0 0.0 1.1 1 0 0 1 1 1 0 Polyomavirus coat protein NHL PF01436.21 CDJ84596.1 - 0.00039 20.3 0.0 7.3 6.8 0.0 4.3 4 0 0 4 4 4 2 NHL repeat SGL PF08450.12 CDJ84596.1 - 0.0015 18.2 0.0 0.0051 16.4 0.0 1.9 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region CCDC73 PF15818.5 CDJ84596.1 - 0.046 11.6 0.7 0.061 11.2 0.7 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 73 family ILEI PF15711.5 CDJ84597.1 - 2.3e-39 133.7 0.0 1.5e-22 79.8 0.0 2.6 2 0 0 2 2 2 2 Interleukin-like EMT inducer GNT-I PF03071.15 CDJ84597.1 - 3.4e-05 22.8 0.0 9.3e-05 21.4 0.0 1.8 2 1 0 2 2 2 1 GNT-I family Arf PF00025.21 CDJ84598.1 - 1.2e-52 177.9 0.4 1.3e-52 177.8 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CDJ84598.1 - 1.1e-11 44.9 0.2 1.7e-11 44.4 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDJ84598.1 - 8.5e-10 38.5 0.1 9.5e-10 38.3 0.1 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CDJ84598.1 - 3.3e-09 36.4 0.2 4.6e-09 35.9 0.2 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.12 CDJ84598.1 - 1e-06 28.3 0.1 1.2e-06 28.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CDJ84598.1 - 2.4e-06 27.1 0.0 2.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Asp PF00026.23 CDJ84599.1 - 5.7e-46 157.4 0.0 6.9e-46 157.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 CDJ84599.1 - 2.7e-07 30.5 0.0 2.1e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal SMC_hinge PF06470.13 CDJ84600.1 - 1.4e-10 41.5 0.0 2.3e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain ABC_tran_CTD PF16326.5 CDJ84600.1 - 0.0088 16.3 1.4 0.016 15.4 0.4 2.0 2 0 0 2 2 2 1 ABC transporter C-terminal domain TPR_MLP1_2 PF07926.12 CDJ84600.1 - 0.015 15.4 0.8 0.025 14.6 0.8 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CHD5 PF04420.14 CDJ84600.1 - 0.043 13.7 0.4 2.2 8.1 0.3 2.1 2 0 0 2 2 2 0 CHD5-like protein GAS PF13851.6 CDJ84600.1 - 0.05 12.9 2.5 0.095 12.0 1.1 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding GrpE PF01025.19 CDJ84600.1 - 0.23 11.1 2.8 0.25 11.0 0.5 1.9 2 0 0 2 2 2 0 GrpE TMF_DNA_bd PF12329.8 CDJ84600.1 - 0.69 9.9 3.8 1.3 9.0 3.8 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding BTB_2 PF02214.22 CDJ84601.1 - 1e-18 67.5 0.0 2e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 CDJ84601.1 - 0.069 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain WD40 PF00400.32 CDJ84602.1 - 8.9e-20 70.7 8.2 7.7e-06 26.6 2.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ84602.1 - 3.7e-13 49.6 1.7 3.4e-06 27.3 0.0 4.0 2 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 CDJ84602.1 - 0.00043 19.3 1.5 0.029 13.3 0.3 2.5 2 1 0 2 2 2 2 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 CDJ84602.1 - 0.12 11.4 0.0 6.9 5.5 0.0 2.7 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MADF_DNA_bdg PF10545.9 CDJ84603.1 - 0.0012 19.1 1.7 0.0037 17.5 0.1 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 CDJ84603.1 - 0.0016 18.4 0.2 0.0043 17.1 0.2 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain ABC_membrane_2 PF06472.15 CDJ84605.1 - 5.4e-55 186.7 3.8 7.6e-55 186.2 3.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CDJ84605.1 - 2.1e-17 63.9 0.0 3.7e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 CDJ84605.1 - 0.00012 22.5 0.0 0.00022 21.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 CDJ84605.1 - 0.0016 18.2 0.0 0.0066 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CDJ84605.1 - 0.0025 18.4 0.0 0.0061 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CDJ84605.1 - 0.0033 17.1 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CDJ84605.1 - 0.0048 17.2 0.1 0.03 14.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CDJ84605.1 - 0.012 15.6 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF3452 PF11934.8 CDJ84605.1 - 0.028 14.0 1.6 1.5 8.4 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) NACHT PF05729.12 CDJ84605.1 - 0.073 13.0 0.0 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Cytidylate_kin PF02224.18 CDJ84605.1 - 0.086 12.6 0.2 0.42 10.3 0.2 2.0 1 1 0 1 1 1 0 Cytidylate kinase Rad17 PF03215.15 CDJ84605.1 - 0.16 11.8 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain MFS_1 PF07690.16 CDJ84606.1 - 3.7e-48 164.2 35.7 1.9e-46 158.6 19.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ84606.1 - 5.8e-13 48.5 9.6 5.8e-13 48.5 9.6 2.3 1 1 0 2 2 2 1 Sugar (and other) transporter Spore_III_AF PF09581.10 CDJ84606.1 - 0.033 14.2 0.2 0.047 13.7 0.2 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) GPHR_N PF12537.8 CDJ84606.1 - 0.52 10.4 3.1 1.3 9.2 0.2 2.8 3 0 0 3 3 3 0 The Golgi pH Regulator (GPHR) Family N-terminal S_4TM PF18159.1 CDJ84606.1 - 0.91 8.8 4.4 5 6.3 1.1 2.4 2 1 0 2 2 2 0 SMODS-associating 4TM effector domain EAF PF09816.9 CDJ84608.1 - 1.4e-21 76.8 1.1 2.5e-21 76.0 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor Syja_N PF02383.18 CDJ84609.1 - 2.1e-86 290.1 0.1 2.8e-86 289.7 0.1 1.2 1 0 0 1 1 1 1 SacI homology domain Collagen PF01391.18 CDJ84610.1 - 6.5e-22 77.1 99.7 3.4e-09 36.3 32.5 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ84610.1 - 9.8e-09 35.2 0.5 1.4e-08 34.6 0.5 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain DUF2650 PF10853.8 CDJ84611.1 - 0.0037 16.9 1.0 0.0074 16.0 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2650) Peptidase_C1 PF00112.23 CDJ84612.1 - 7e-87 291.1 0.2 9.7e-87 290.6 0.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CDJ84612.1 - 5.2e-10 39.6 0.4 9.6e-10 38.8 0.4 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CDJ84612.1 - 6.2e-05 22.0 0.2 0.016 14.0 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Retrotrans_gag PF03732.17 CDJ84612.1 - 0.039 14.2 0.1 0.078 13.3 0.1 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein DUF2508 PF10704.9 CDJ84612.1 - 0.12 12.5 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) Gal-bind_lectin PF00337.22 CDJ84613.1 - 4.7e-71 236.6 0.0 1.2e-36 125.2 0.0 2.0 2 0 0 2 2 2 2 Galactoside-binding lectin Alginate_lyase2 PF08787.11 CDJ84613.1 - 0.037 13.9 0.1 0.24 11.2 0.1 2.1 1 1 0 1 1 1 0 Alginate lyase Gal-bind_lectin PF00337.22 CDJ84614.1 - 1.5e-98 325.5 0.1 6.7e-30 103.4 0.0 6.6 5 2 1 6 6 6 6 Galactoside-binding lectin CBM64 PF18666.1 CDJ84614.1 - 0.072 13.2 0.4 25 5.0 0.1 3.0 2 0 0 2 2 2 0 Carbohydrate-binding module 64 DUF667 PF05018.13 CDJ84614.1 - 0.086 12.6 0.5 6.3 6.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF667) Gal-bind_lectin PF00337.22 CDJ84615.1 - 8.8e-96 316.6 0.0 3.8e-28 97.7 0.0 4.7 4 1 0 4 4 4 4 Galactoside-binding lectin LIM PF00412.22 CDJ84616.1 - 1.7e-25 89.0 21.0 2.1e-13 50.3 2.6 3.1 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.22 CDJ84616.1 - 0.006 16.4 23.1 1.3 9.0 7.6 3.7 3 1 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) DiS_P_DiS PF06750.13 CDJ84616.1 - 0.2 11.8 0.1 0.2 11.8 0.1 3.4 3 1 1 4 4 4 0 Bacterial Peptidase A24 N-terminal domain HEXIM PF15313.6 CDJ84617.1 - 1e-26 93.8 7.7 1e-26 93.8 7.7 1.9 2 0 0 2 2 2 1 Hexamethylene bis-acetamide-inducible protein Rif1_N PF12231.8 CDJ84617.1 - 0.041 12.9 1.8 0.059 12.4 1.8 1.2 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal Guanylate_cyc PF00211.20 CDJ84618.1 - 3.6e-103 342.9 0.2 3.5e-55 186.5 0.1 2.5 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 CDJ84618.1 - 0.0022 17.2 0.4 0.0022 17.2 0.4 4.6 3 2 1 4 4 4 1 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF1053 PF06327.14 CDJ84618.1 - 0.0043 17.6 0.0 0.036 14.6 0.0 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1053) SH2_2 PF14633.6 CDJ84619.1 - 1.2e-68 230.8 0.1 1.2e-68 230.8 0.1 2.5 3 0 0 3 3 3 1 SH2 domain HHH_7 PF14635.6 CDJ84619.1 - 5.9e-40 135.8 0.0 1.3e-39 134.8 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 CDJ84619.1 - 6.9e-23 81.1 0.0 1.7e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 CDJ84619.1 - 4.4e-18 65.8 3.0 1.6e-17 64.0 3.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 S1 PF00575.23 CDJ84619.1 - 2.8e-07 30.8 0.0 9.2e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 S1 RNA binding domain HHH_9 PF17674.1 CDJ84619.1 - 7.8e-07 29.9 0.2 3.7e-06 27.7 0.2 2.3 1 0 0 1 1 1 1 HHH domain Tex_N PF09371.10 CDJ84619.1 - 1.4e-06 28.1 0.0 0.0022 17.7 0.0 3.0 2 1 0 2 2 2 2 Tex-like protein N-terminal domain SPT6_acidic PF14632.6 CDJ84619.1 - 2.9e-06 27.7 35.1 2.9e-06 27.7 35.1 5.8 2 1 3 5 5 4 1 Acidic N-terminal SPT6 HHH_3 PF12836.7 CDJ84619.1 - 5.5e-06 26.5 0.0 1.5e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif SH2 PF00017.24 CDJ84619.1 - 9.7e-06 25.6 0.0 0.00023 21.2 0.0 2.8 2 0 0 2 2 2 1 SH2 domain Tex_YqgF PF16921.5 CDJ84619.1 - 0.14 12.6 0.0 0.34 11.4 0.0 1.7 1 0 0 1 1 1 0 Tex protein YqgF-like domain ABC2_membrane PF01061.24 CDJ84620.2 - 8.1e-08 31.9 6.3 8.1e-08 31.9 6.3 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 CDJ84620.2 - 3.7e-05 24.3 0.0 9.8e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 ABC transporter TAF6_C PF07571.13 CDJ84620.2 - 0.088 13.1 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain DUF4538 PF15061.6 CDJ84620.2 - 0.09 12.5 0.4 0.18 11.6 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Nucleoside_tran PF01733.18 CDJ84621.1 - 5.3e-66 223.1 23.6 5.3e-66 223.1 23.6 2.3 2 1 0 2 2 2 1 Nucleoside transporter Ras PF00071.22 CDJ84622.1 - 2e-60 203.0 0.0 2.6e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ84622.1 - 7.6e-32 110.0 0.1 1.6e-31 109.0 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ84622.1 - 1.3e-12 47.5 0.0 1.8e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ84622.1 - 6.1e-05 23.1 0.0 0.00012 22.2 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ84622.1 - 0.00021 20.9 0.0 0.017 14.7 0.0 2.5 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDJ84622.1 - 0.001 19.0 0.0 1.3 8.9 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 CDJ84622.1 - 0.0026 17.1 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Septin PF00735.18 CDJ84622.1 - 0.081 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Septin SRPRB PF09439.10 CDJ84622.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 CDJ84622.1 - 0.16 11.8 0.0 3.6 7.3 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Peptidase_M16_C PF05193.21 CDJ84623.1 - 3.8e-35 121.5 0.0 1.1e-34 120.0 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CDJ84623.1 - 1.7e-25 89.8 0.0 4.1e-25 88.5 0.0 1.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) SAP30_Sin3_bdg PF13867.6 CDJ84623.1 - 0.1 12.9 0.0 0.32 11.4 0.0 1.8 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Homeodomain PF00046.29 CDJ84624.1 - 1.9e-22 78.9 4.4 1.9e-22 78.9 4.4 1.9 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CDJ84624.1 - 0.015 15.2 0.2 0.015 15.2 0.2 3.2 3 1 0 3 3 3 0 Homeobox KN domain TmoB PF06234.12 CDJ84624.1 - 3.3 7.9 4.8 2.4 8.3 0.2 2.6 3 0 0 3 3 3 0 Toluene-4-monooxygenase system protein B (TmoB) MSP1_C PF07462.11 CDJ84624.1 - 4.1 6.0 6.7 6.1 5.4 6.7 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus ASPRs PF17641.2 CDJ84625.1 - 0.15 12.4 0.0 0.16 12.3 0.0 1.3 1 1 0 1 1 1 0 Ancylostoma-associated secreted protein related ASPRs PF17641.2 CDJ84626.1 - 0.044 14.1 0.1 0.42 10.9 0.0 2.0 1 1 1 2 2 2 0 Ancylostoma-associated secreted protein related Exo_endo_phos_2 PF14529.6 CDJ84627.1 - 0.00026 20.8 0.1 0.0013 18.6 0.1 2.1 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase RP-C_C PF11800.8 CDJ84627.1 - 0.16 12.1 2.0 0.23 11.5 2.0 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region MIP PF00230.20 CDJ84628.1 - 2.3e-39 135.4 11.3 2.9e-39 135.1 11.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein Guanylate_cyc PF00211.20 CDJ84632.1 - 4.2e-61 205.8 0.0 5.5e-61 205.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 CDJ84632.1 - 1.4e-05 24.6 0.3 2.4e-05 23.9 0.3 1.3 1 0 0 1 1 1 1 Heme NO binding associated dsDNA_bind PF01984.20 CDJ84632.1 - 0.0052 17.0 0.0 0.0093 16.2 0.0 1.3 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Corona_6B_7B PF03262.13 CDJ84632.1 - 0.056 12.9 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 Coronavirus 6B/7B protein CoA_transf_3 PF02515.17 CDJ84633.1 - 5.7e-64 216.5 0.0 8.7e-64 215.9 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III AAA PF00004.29 CDJ84634.1 - 4.1e-40 137.3 0.0 1.4e-39 135.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ84634.1 - 8.1e-12 44.8 0.2 3.3e-11 42.8 0.0 2.3 2 0 0 2 2 1 1 AAA+ lid domain Vps4_C PF09336.10 CDJ84634.1 - 1.4e-05 25.0 0.0 4.6e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 CDJ84634.1 - 3.9e-05 23.7 0.1 0.00021 21.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CDJ84634.1 - 0.00053 20.0 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CDJ84634.1 - 0.0011 18.7 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CDJ84634.1 - 0.0029 17.8 0.0 0.0073 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CDJ84634.1 - 0.0033 17.2 0.0 0.0073 16.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 CDJ84634.1 - 0.0035 17.1 0.1 0.016 15.0 0.0 2.0 1 1 1 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 CDJ84634.1 - 0.0035 17.6 1.5 0.035 14.4 0.1 2.7 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 CDJ84634.1 - 0.0045 17.4 1.6 0.017 15.5 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 CDJ84634.1 - 0.011 15.9 0.0 0.039 14.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 CDJ84634.1 - 0.019 14.4 0.1 0.036 13.4 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF615 PF04751.14 CDJ84634.1 - 0.023 14.7 1.1 0.063 13.3 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF615) AAA_24 PF13479.6 CDJ84634.1 - 0.026 14.3 0.0 0.084 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 CDJ84634.1 - 0.028 13.8 0.6 3.4 7.0 0.0 2.7 2 1 1 3 3 3 0 KaiC AAA_18 PF13238.6 CDJ84634.1 - 0.028 14.9 1.8 0.045 14.3 0.2 2.3 2 1 0 2 2 1 0 AAA domain NACHT PF05729.12 CDJ84634.1 - 0.031 14.2 0.1 0.3 11.0 0.1 2.3 1 1 0 2 2 2 0 NACHT domain PhoH PF02562.16 CDJ84634.1 - 0.031 13.7 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 CDJ84634.1 - 0.036 14.3 0.6 0.26 11.5 0.6 2.4 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 CDJ84634.1 - 0.039 13.2 0.0 0.074 12.2 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain ABC_tran PF00005.27 CDJ84634.1 - 0.061 13.8 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 CDJ84634.1 - 0.073 13.5 0.0 0.15 12.4 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 CDJ84634.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 CDJ84634.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF3813 PF12758.7 CDJ84634.1 - 0.16 12.4 0.4 1.3 9.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) Pheromone PF08015.11 CDJ84634.1 - 0.19 12.8 2.1 0.29 12.2 0.2 2.2 2 0 0 2 2 2 0 Fungal mating-type pheromone HECT PF00632.25 CDJ84635.1 - 1.6e-94 316.8 0.1 2.5e-94 316.2 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.12 CDJ84635.1 - 5.3e-73 246.1 0.0 5.3e-73 246.1 0.0 5.2 5 0 0 5 5 5 2 Domain of Unknown Function (DUF913) UBM PF14377.6 CDJ84635.1 - 5e-23 79.8 25.6 2.4e-10 39.5 0.8 4.4 4 0 0 4 4 4 3 Ubiquitin binding region DUF908 PF06012.12 CDJ84635.1 - 6.6e-16 58.7 18.3 1.5e-11 44.3 0.6 4.0 4 0 0 4 4 4 2 Domain of Unknown Function (DUF908) UBA PF00627.31 CDJ84635.1 - 5.1e-06 26.3 0.0 2.4e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 UBA/TS-N domain WWE PF02825.20 CDJ84635.1 - 2.3e-05 24.9 0.0 7.9e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 WWE domain CSTF_C PF14304.6 CDJ84635.1 - 0.92 9.1 5.1 17 5.1 0.0 3.7 3 0 0 3 3 3 0 Transcription termination and cleavage factor C-terminal TIM21 PF08294.11 CDJ84636.1 - 2.2e-35 121.7 0.1 3.3e-35 121.1 0.1 1.2 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 CDJ84636.1 - 0.019 14.7 0.0 0.043 13.6 0.0 1.5 1 1 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 SRR1 PF07985.12 CDJ84636.1 - 0.03 14.3 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 SRR1 Gram_pos_anchor PF00746.21 CDJ84636.1 - 0.34 10.9 1.0 0.62 10.1 1.0 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Ribosomal_L2 PF00181.23 CDJ84637.1 - 2.6e-16 59.3 0.0 4.5e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L2_C PF03947.18 CDJ84637.1 - 1.1e-10 41.8 0.0 2.9e-10 40.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Sugar_tr PF00083.24 CDJ84638.1 - 9.2e-51 173.1 16.7 7.3e-45 153.7 13.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CDJ84638.1 - 1.4e-08 34.1 61.7 4.3e-06 25.9 23.2 3.2 1 1 2 3 3 3 3 Major Facilitator Superfamily ELO PF01151.18 CDJ84639.1 - 1.4e-30 106.6 13.6 1.7e-30 106.4 13.6 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF5373 PF17343.2 CDJ84639.1 - 6.7 6.5 10.0 2 8.3 0.8 2.8 1 1 2 3 3 3 0 Family of unknown function (DUF5373) 7TM_GPCR_Srx PF10328.9 CDJ84640.1 - 0.00048 19.8 16.5 0.00048 19.8 16.5 1.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx US6 PF17616.2 CDJ84640.1 - 0.011 15.7 2.5 0.02 14.8 2.5 1.4 1 0 0 1 1 1 0 Viral unique short region 6 DUF485 PF04341.12 CDJ84640.1 - 0.012 15.6 2.9 0.012 15.6 2.9 2.2 2 1 0 2 2 2 0 Protein of unknown function, DUF485 DUF5326 PF17260.2 CDJ84640.1 - 0.041 14.0 0.9 0.041 14.0 0.9 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5326) 7tm_1 PF00001.21 CDJ84640.1 - 0.11 11.8 11.9 0.019 14.3 7.8 1.7 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Tmemb_18A PF09771.9 CDJ84640.1 - 1.4 9.3 8.3 8 6.9 2.4 2.6 1 1 1 2 2 2 0 Transmembrane protein 188 RVT_1 PF00078.27 CDJ84641.1 - 2.5e-25 89.3 0.0 3.8e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Bestrophin PF01062.21 CDJ84642.1 - 4.7e-48 164.1 0.3 5.8e-48 163.8 0.3 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PH PF00169.29 CDJ84643.1 - 1.5e-09 38.3 0.6 5.3e-09 36.5 0.1 2.2 2 0 0 2 2 2 1 PH domain Myosin_TH1 PF06017.13 CDJ84643.1 - 0.071 12.8 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding PHD PF00628.29 CDJ84644.1 - 2.1e-12 46.7 4.8 2.1e-12 46.7 4.8 2.5 2 0 0 2 2 1 1 PHD-finger zf-RING_2 PF13639.6 CDJ84644.1 - 1.1e-07 32.1 25.3 2.1e-07 31.2 9.7 2.6 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.7 CDJ84644.1 - 0.00024 21.3 4.5 0.00024 21.3 4.5 3.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDJ84644.1 - 0.0046 16.8 8.6 0.0046 16.8 8.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.6 CDJ84644.1 - 0.005 16.4 0.2 0.015 14.8 0.2 1.9 1 0 0 1 1 1 1 PHD-finger zf-ANAPC11 PF12861.7 CDJ84644.1 - 0.15 12.1 11.9 0.84 9.7 2.6 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 CDJ84644.1 - 0.57 10.4 11.1 4.4 7.5 3.1 3.4 3 0 0 3 3 3 0 zinc RING finger of MSL2 ADK_lid PF05191.14 CDJ84644.1 - 0.73 9.9 6.0 1.6 8.8 0.4 3.2 3 0 0 3 3 3 0 Adenylate kinase, active site lid Zn_ribbon_17 PF17120.5 CDJ84644.1 - 0.75 9.5 12.5 0.11 12.2 4.1 2.5 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 CDJ84644.1 - 1.3 8.9 23.4 0.012 15.5 8.4 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 CDJ84644.1 - 4.1 7.6 14.6 11 6.3 3.8 2.9 2 0 0 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 CDJ84644.1 - 6.9 6.8 18.2 0.014 15.4 6.4 2.7 2 0 0 2 2 1 0 RING-type zinc-finger SapB_2 PF03489.17 CDJ84645.1 - 9.4e-08 32.0 1.1 9.4e-08 32.0 1.1 2.3 3 0 0 3 3 3 1 Saposin-like type B, region 2 SapB_1 PF05184.15 CDJ84645.1 - 0.0011 18.9 3.0 0.0011 18.9 3.0 2.7 4 1 0 4 4 4 1 Saposin-like type B, region 1 ZYG-11_interact PF05884.12 CDJ84645.1 - 0.14 11.5 0.1 0.2 11.1 0.1 1.3 1 1 0 1 1 1 0 Interactor of ZYG-11 Pilin_N PF07790.11 CDJ84645.1 - 0.16 12.9 2.4 0.22 12.5 2.4 1.3 1 1 0 1 1 1 0 Archaeal Type IV pilin, N-terminal SNF2_N PF00176.23 CDJ84646.1 - 2.1e-44 151.7 0.0 3.9e-44 150.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ84646.1 - 1.1e-17 64.4 0.0 4.4e-17 62.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ84646.1 - 6.1e-06 26.3 0.0 3.4e-05 23.9 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CDJ84646.1 - 0.0028 16.9 1.1 0.24 10.6 0.0 2.8 2 1 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase T2SS_PulS_OutS PF09691.10 CDJ84647.1 - 0.037 14.2 0.5 14 5.9 0.0 2.7 3 0 0 3 3 3 0 Type II secretion system pilotin lipoprotein (PulS_OutS) DUF3718 PF12514.8 CDJ84647.1 - 0.039 14.1 0.0 5.8 7.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3718) Torus PF16131.5 CDJ84647.1 - 0.054 14.2 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 Torus domain DUF3375 PF11855.8 CDJ84647.1 - 0.59 9.0 3.0 0.24 10.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3375) DUF1574 PF07611.11 CDJ84648.1 - 0.25 10.6 0.0 0.35 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) VGCC_alpha2 PF08473.11 CDJ84649.1 - 1.3e-06 27.5 3.6 0.00023 20.1 1.3 3.3 2 1 0 2 2 2 2 Neuronal voltage-dependent calcium channel alpha 2acd 7tm_1 PF00001.21 CDJ84650.1 - 1.6e-07 30.9 0.0 1.6e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Tho2 PF11262.8 CDJ84651.1 - 7.3e-78 261.8 1.6 7.3e-78 261.8 1.6 3.0 4 0 0 4 4 4 1 Transcription factor/nuclear export subunit protein 2 RVT_1 PF00078.27 CDJ84654.1 - 6.4e-25 88.0 0.0 8.3e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) I-set PF07679.16 CDJ84655.1 - 6.3e-43 144.8 0.0 3.5e-11 43.0 0.0 4.8 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ84655.1 - 3.9e-42 142.7 0.0 1.4e-10 41.6 0.0 4.8 4 0 0 4 4 4 4 Immunoglobulin domain fn3 PF00041.21 CDJ84655.1 - 8.7e-36 122.1 14.5 2.9e-07 30.7 0.2 5.5 5 0 0 5 5 5 5 Fibronectin type III domain ig PF00047.25 CDJ84655.1 - 1e-27 96.1 0.0 4.3e-08 33.2 0.0 4.9 5 0 0 5 5 5 4 Immunoglobulin domain Ig_2 PF13895.6 CDJ84655.1 - 4.3e-27 94.3 0.0 2.6e-06 27.7 0.0 4.8 4 0 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 CDJ84655.1 - 9.4e-12 45.1 3.5 0.018 15.2 0.1 6.5 4 3 2 6 6 6 2 Immunoglobulin V-set domain Ig_6 PF18452.1 CDJ84655.1 - 0.012 15.2 0.0 7.4 6.2 0.0 3.4 3 0 0 3 3 3 0 Immunoglobulin domain C2-set_2 PF08205.12 CDJ84655.1 - 0.013 15.6 0.0 0.1 12.6 0.0 2.5 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 CDJ84655.1 - 0.018 15.1 0.1 3.6 7.7 0.0 3.7 3 1 0 3 3 3 0 C17orf99 Ig domain BiPBP_C PF06832.12 CDJ84655.1 - 0.02 14.9 0.0 0.58 10.2 0.0 2.9 3 0 0 3 3 3 0 Penicillin-Binding Protein C-terminus Family C1-set PF07654.15 CDJ84655.1 - 0.14 12.6 3.3 0.38 11.1 0.0 3.2 4 0 0 4 4 3 0 Immunoglobulin C1-set domain Plexin_cytopl PF08337.12 CDJ84656.1 - 2.5e-136 455.6 0.0 4.2e-136 454.9 0.0 1.2 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.24 CDJ84656.1 - 2.8e-31 107.4 12.4 4.7e-11 42.6 0.7 5.3 5 0 0 5 5 5 4 IPT/TIG domain Sema PF01403.19 CDJ84656.1 - 1.3e-26 93.5 0.5 6.3e-26 91.1 0.0 2.2 2 1 0 2 2 2 1 Sema domain PSI PF01437.25 CDJ84656.1 - 7.3e-13 48.9 54.2 2.3e-05 24.8 11.8 3.8 3 0 0 3 3 3 3 Plexin repeat TIG_2 PF18020.1 CDJ84656.1 - 4.9e-12 46.3 0.0 2.8e-10 40.7 0.0 2.7 2 0 0 2 2 2 1 TIG domain found in plexin Roc PF08477.13 CDJ84657.1 - 5.2e-07 29.9 0.0 6e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ84657.1 - 9e-06 25.3 0.0 1.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CDJ84657.1 - 0.0004 20.0 0.0 0.00052 19.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CDJ84657.1 - 0.011 15.1 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region G-alpha PF00503.20 CDJ84657.1 - 0.019 14.2 0.0 2.6 7.1 0.0 2.0 1 1 1 2 2 2 0 G-protein alpha subunit AAA_18 PF13238.6 CDJ84657.1 - 0.036 14.6 0.0 0.039 14.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 CDJ84657.1 - 0.061 12.8 0.0 0.067 12.6 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 CDJ84657.1 - 0.2 11.4 0.0 0.24 11.2 0.0 1.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation LUC7 PF03194.15 CDJ84658.1 - 7e-70 235.6 13.6 8.9e-70 235.2 13.6 1.1 1 0 0 1 1 1 1 LUC7 N_terminus TPR_14 PF13428.6 CDJ84659.1 - 0.00011 22.7 0.6 17 6.6 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat Mcl1_mid PF12341.8 CDJ84659.1 - 0.042 13.2 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region TPR_16 PF13432.6 CDJ84659.1 - 0.11 13.2 0.0 0.58 10.9 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat NatB_MDM20 PF09797.9 CDJ84660.1 - 6.7e-61 206.3 0.0 1e-60 205.7 0.0 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit EAP30 PF04157.16 CDJ84660.1 - 0.00039 19.8 0.1 0.0021 17.4 0.0 2.0 2 0 0 2 2 2 1 EAP30/Vps36 family Mating_N PF12731.7 CDJ84660.1 - 0.12 12.5 0.1 3.2 7.9 0.1 2.6 2 0 0 2 2 2 0 Mating-type protein beta 1 DOMON PF03351.17 CDJ84662.1 - 1e-11 45.1 0.5 1.3e-11 44.8 0.5 1.1 1 0 0 1 1 1 1 DOMON domain RRM_1 PF00076.22 CDJ84664.1 - 2.6e-13 49.6 0.0 4.3e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSRP PF17069.5 CDJ84664.1 - 0.00024 20.8 40.3 0.00039 20.1 40.3 1.3 1 0 0 1 1 1 1 Arginine/Serine-Rich protein 1 PRP38_assoc PF12871.7 CDJ84664.1 - 0.0014 19.2 43.4 0.0014 19.2 43.4 2.0 2 0 0 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Apt1 PF10351.9 CDJ84664.1 - 0.0058 15.6 14.4 0.0072 15.2 14.4 1.0 1 0 0 1 1 1 1 Golgi-body localisation protein domain GRP PF07172.11 CDJ84664.1 - 0.021 15.5 6.4 0.021 15.5 6.4 2.2 2 1 0 2 2 2 0 Glycine rich protein family Mem_trans PF03547.18 CDJ84664.1 - 0.038 12.4 3.6 0.042 12.3 3.6 1.2 1 0 0 1 1 1 0 Membrane transport protein CDC45 PF02724.14 CDJ84664.1 - 0.06 11.6 17.9 0.079 11.2 17.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4363 PF14276.6 CDJ84664.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) RNA_bind PF08675.11 CDJ84664.1 - 0.15 12.1 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA binding domain Presenilin PF01080.17 CDJ84664.1 - 0.18 10.6 8.4 0.18 10.6 8.4 1.1 1 0 0 1 1 1 0 Presenilin Transformer PF06495.11 CDJ84664.1 - 0.42 10.7 36.7 0.02 15.0 31.0 1.7 2 0 0 2 2 2 0 Fruit fly transformer protein RAP1 PF07218.11 CDJ84664.1 - 0.47 8.7 5.2 0.52 8.5 5.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ndc1_Nup PF09531.10 CDJ84664.1 - 0.53 8.9 5.9 0.54 8.9 5.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.16 CDJ84664.1 - 0.95 9.5 3.6 1.2 9.1 3.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF936 PF06075.12 CDJ84664.1 - 1.2 7.9 16.8 1.4 7.7 16.8 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Peptidase_S64 PF08192.11 CDJ84664.1 - 2.9 6.3 7.4 3.2 6.1 7.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 SRP-alpha_N PF04086.13 CDJ84664.1 - 3.1 7.6 15.5 4.1 7.2 15.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal GREB1 PF15782.5 CDJ84664.1 - 4.1 4.4 5.0 4.4 4.3 5.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CPSF100_C PF13299.6 CDJ84664.1 - 7.3 6.8 10.1 24 5.1 10.1 1.7 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Cyclin_N PF00134.23 CDJ84665.1 - 1.5e-10 40.9 1.6 2.1e-10 40.5 0.7 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF3391 PF11871.8 CDJ84666.1 - 0.2 12.2 9.9 1.2 9.7 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) EF-hand_14 PF17959.1 CDJ84666.1 - 3.5 8.0 6.3 0.36 11.2 0.9 2.2 2 2 0 2 2 2 0 EF-hand domain MLANA PF14991.6 CDJ84667.1 - 0.093 13.0 1.5 0.14 12.4 1.5 1.2 1 0 0 1 1 1 0 Protein melan-A DUF4713 PF15831.5 CDJ84667.1 - 0.23 11.9 10.0 0.63 10.5 10.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) DUF4690 PF15756.5 CDJ84667.1 - 5.8 7.6 5.6 11 6.7 5.6 1.4 1 0 0 1 1 1 0 Small Novel Rich in Cartilage 7tm_1 PF00001.21 CDJ84669.1 - 2.4e-22 79.5 1.2 2.9e-22 79.2 1.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ84669.1 - 2e-07 30.7 2.7 2.4e-07 30.4 2.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 CDJ84669.1 - 0.00023 20.9 5.4 0.00031 20.5 5.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Git3 PF11710.8 CDJ84669.1 - 0.006 16.4 1.9 0.0074 16.1 1.9 1.1 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 MFS_1 PF07690.16 CDJ84669.1 - 0.029 13.3 5.3 0.037 12.9 5.3 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily Holin_SPP1 PF04688.13 CDJ84669.1 - 0.15 12.2 0.8 0.32 11.2 0.8 1.5 1 0 0 1 1 1 0 SPP1 phage holin DUF1759 PF03564.15 CDJ84671.1 - 0.0013 18.6 0.4 0.0026 17.7 0.1 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1759) Retrotran_gag_2 PF14223.6 CDJ84671.1 - 0.0041 16.8 0.3 0.0051 16.5 0.3 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type YejG PF13989.6 CDJ84671.1 - 0.056 13.9 0.1 0.23 11.9 0.0 1.8 2 0 0 2 2 2 0 YejG-like protein CNOT1_HEAT PF16418.5 CDJ84671.1 - 0.061 13.4 0.1 0.083 13.0 0.1 1.3 1 1 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Aldo_ket_red PF00248.21 CDJ84672.1 - 0.00027 20.3 0.0 0.00045 19.5 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Diedel PF13164.6 CDJ84673.1 - 0.032 14.7 0.1 0.26 11.8 0.1 2.0 2 0 0 2 2 2 0 Diedel Glyco_transf_22 PF03901.17 CDJ84675.1 - 1.4e-63 215.6 28.1 1.8e-63 215.2 28.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family tRNA-synt_1 PF00133.22 CDJ84676.1 - 5.6e-155 517.0 0.0 2.6e-153 511.5 0.0 2.6 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDJ84676.1 - 9.6e-25 87.3 0.0 2.7e-24 85.9 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CDJ84676.1 - 3.1e-13 49.2 0.1 7.3e-06 25.0 0.1 4.1 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CDJ84676.1 - 1.1e-05 25.1 0.1 0.00019 21.0 0.0 2.5 2 1 1 3 3 3 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1f PF01921.18 CDJ84676.1 - 0.036 13.0 0.0 3.6 6.4 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (K) tRNA-synt_1b PF00579.25 CDJ84676.1 - 0.17 11.1 0.6 0.51 9.6 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Fels1 PF05666.11 CDJ84677.1 - 0.017 14.7 0.6 0.028 14.0 0.1 1.6 2 0 0 2 2 2 0 Fels-1 Prophage Protein-like RVT_1 PF00078.27 CDJ84678.1 - 9.1e-41 139.8 0.0 2e-26 92.9 0.0 2.0 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) EntA_Immun PF08951.10 CDJ84678.1 - 0.0072 16.7 0.0 5.9 7.3 0.0 2.4 2 0 0 2 2 2 2 Enterocin A Immunity SseB_C PF14581.6 CDJ84678.1 - 0.061 13.4 0.0 4.3 7.5 0.0 2.3 2 0 0 2 2 2 0 SseB protein C-terminal domain SRP54_N PF02881.19 CDJ84678.1 - 0.12 12.7 0.1 14 6.0 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain Ribonuclease_P PF00825.18 CDJ84678.1 - 0.12 12.4 0.1 17 5.5 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease P RRM_Rrp7 PF17799.1 CDJ84678.1 - 0.13 12.1 0.0 15 5.4 0.0 2.2 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain eIF-3c_N PF05470.12 CDJ84678.1 - 0.19 10.0 0.0 11 4.2 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Ribosomal_S28e PF01200.18 CDJ84678.1 - 0.37 10.8 3.7 6.2 6.9 0.2 2.8 2 2 0 2 2 2 0 Ribosomal protein S28e CYTH PF01928.21 CDJ84681.1 - 3.8e-18 66.0 0.1 4.7e-18 65.7 0.1 1.1 1 0 0 1 1 1 1 CYTH domain Cas_DxTHG PF09455.10 CDJ84683.1 - 0.0032 17.1 0.5 0.0039 16.8 0.5 1.1 1 0 0 1 1 1 1 CRISPR-associated (Cas) DxTHG family Toxin-deaminase PF14424.6 CDJ84683.1 - 0.01 16.0 1.0 0.016 15.3 1.0 1.3 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases CRR7 PF12095.8 CDJ84683.1 - 0.057 13.9 1.0 0.36 11.3 0.2 2.4 3 0 0 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 PhaP_Bmeg PF09602.10 CDJ84683.1 - 0.54 10.2 4.6 3.1 7.7 0.2 2.2 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) SseC PF04888.12 CDJ84683.1 - 0.55 9.8 6.1 0.99 8.9 6.1 1.4 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family GlutR_dimer PF00745.20 CDJ84683.1 - 0.81 10.2 6.3 0.36 11.3 0.4 2.4 2 1 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Methyltr_RsmB-F PF01189.17 CDJ84684.1 - 1.5e-23 83.5 0.0 1.9e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CDJ84684.1 - 0.018 15.2 0.1 0.027 14.6 0.1 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase RVT_1 PF00078.27 CDJ84687.1 - 2.9e-11 43.3 0.0 3.9e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Aldo_ket_red PF00248.21 CDJ84688.1 - 7e-59 199.4 0.0 9.9e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family EGF_CA PF07645.15 CDJ84689.1 - 2.6e-39 133.1 150.9 5.6e-11 42.5 10.0 10.9 10 2 0 10 10 8 6 Calcium-binding EGF domain EGF_3 PF12947.7 CDJ84689.1 - 3.1e-22 78.5 112.6 1.7e-08 34.5 2.4 10.4 9 2 1 10 10 9 6 EGF domain cEGF PF12662.7 CDJ84689.1 - 3.6e-12 46.0 88.7 0.00023 21.0 1.5 11.3 10 1 0 10 10 10 7 Complement Clr-like EGF-like hEGF PF12661.7 CDJ84689.1 - 4.9e-11 42.8 121.8 8.1e-05 23.1 3.1 13.1 12 1 0 12 12 12 8 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CDJ84689.1 - 1.2e-06 28.5 35.5 9.4e-05 22.4 6.9 10.6 11 0 0 11 11 11 4 MSP1 EGF domain 1 EGF PF00008.27 CDJ84689.1 - 5.7e-06 26.5 141.1 0.0027 18.0 6.8 12.8 12 1 1 13 13 12 7 EGF-like domain NIDO PF06119.14 CDJ84689.1 - 3.6e-05 24.6 0.0 0.00019 22.3 0.0 2.3 1 1 0 1 1 1 1 Nidogen-like TMEM154 PF15102.6 CDJ84689.1 - 6e-05 23.0 5.6 0.00017 21.5 0.0 2.3 2 0 0 2 2 2 1 TMEM154 protein family FXa_inhibition PF14670.6 CDJ84689.1 - 0.016 15.5 7.0 0.016 15.5 7.0 11.1 8 2 2 10 10 8 0 Coagulation Factor Xa inhibitory site Cpta_toxin PF07254.12 CDJ84689.1 - 0.059 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Membrane-bound toxin component of toxin-antitoxin system Mucin PF01456.17 CDJ84689.1 - 2.6 8.0 27.5 0.022 14.7 13.6 3.1 3 0 0 3 3 3 0 Mucin-like glycoprotein Sugar_tr PF00083.24 CDJ84690.1 - 1.7e-28 99.7 19.2 2.2e-28 99.4 19.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ84690.1 - 2.3e-16 59.7 22.0 3.9e-16 58.9 22.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CDJ84690.1 - 0.0033 15.9 1.6 0.0033 15.9 1.6 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CDJ84691.1 - 4e-29 101.8 32.3 6.1e-29 101.2 32.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ84691.1 - 4.4e-19 68.6 39.8 1.8e-18 66.6 30.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_25 PF13649.6 CDJ84692.1 - 2.2e-05 25.1 0.0 7.8e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Spermine_synth PF01564.17 CDJ84692.1 - 0.0016 17.9 0.1 0.0031 16.9 0.1 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 CDJ84692.1 - 0.0031 17.4 0.0 0.005 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CDJ84692.1 - 0.0077 16.0 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 CDJ84692.1 - 0.022 15.4 0.0 0.049 14.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_5 PF01795.19 CDJ84692.1 - 0.025 14.1 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 MraW methylase family MTS PF05175.14 CDJ84692.1 - 0.03 13.9 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain N2227 PF07942.12 CDJ84692.1 - 0.04 13.1 0.1 0.99 8.5 0.0 2.1 2 0 0 2 2 2 0 N2227-like protein Methyltransf_31 PF13847.6 CDJ84692.1 - 0.052 13.3 0.0 0.16 11.7 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 CDJ84692.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ecTbetaR2 PF08917.10 CDJ84692.1 - 0.16 11.9 1.6 0.19 11.7 0.3 1.8 2 0 0 2 2 2 0 Transforming growth factor beta receptor 2 ectodomain CMAS PF02353.20 CDJ84693.1 - 0.066 12.5 0.2 0.11 11.7 0.2 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Remorin_C PF03763.13 CDJ84693.1 - 0.076 12.9 4.3 0.13 12.2 4.2 1.4 1 1 0 1 1 1 0 Remorin, C-terminal region Peptidase_S9 PF00326.21 CDJ84694.1 - 9e-41 139.7 0.0 2e-40 138.6 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CDJ84694.1 - 4.4e-11 42.9 0.5 4.9e-06 26.4 0.2 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ84694.1 - 3.1e-10 39.7 0.5 1.3e-05 24.5 0.2 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 CDJ84694.1 - 7.1e-09 35.5 0.1 2.1e-08 34.0 0.1 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 CDJ84694.1 - 2.5e-08 33.8 0.0 0.00026 20.7 0.0 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 CDJ84694.1 - 7.5e-05 23.4 0.5 0.00047 20.8 0.5 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.14 CDJ84694.1 - 0.0086 15.4 0.1 0.015 14.6 0.1 1.3 1 0 0 1 1 1 1 Secretory lipase PAF-AH_p_II PF03403.13 CDJ84694.1 - 0.0092 14.5 0.0 0.058 11.9 0.0 1.9 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II BAAT_C PF08840.11 CDJ84694.1 - 0.013 15.5 0.0 0.11 12.4 0.0 2.2 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 CDJ84694.1 - 0.045 13.4 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF2920 PF11144.8 CDJ84694.1 - 0.079 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Abhydrolase_3 PF07859.13 CDJ84694.1 - 0.12 12.3 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold FRB_dom PF08771.11 CDJ84695.1 - 0.0027 18.1 0.1 0.0037 17.6 0.1 1.3 1 1 0 1 1 1 1 FKBP12-rapamycin binding domain Mis14 PF08641.12 CDJ84695.1 - 0.0065 16.8 3.1 0.0081 16.5 3.1 1.2 1 0 0 1 1 1 1 Kinetochore protein Mis14 like Lipase_chap PF03280.14 CDJ84695.1 - 0.015 15.2 7.2 0.021 14.8 7.0 1.3 1 1 0 1 1 1 0 Proteobacterial lipase chaperone protein RapH_N PF18801.1 CDJ84695.1 - 0.026 14.6 0.3 7.4 6.7 0.2 2.4 2 0 0 2 2 2 0 response regulator aspartate phosphatase H, N terminal Hormone_2 PF00123.20 CDJ84695.1 - 0.1 12.5 0.2 20 5.2 0.1 2.4 2 0 0 2 2 2 0 Peptide hormone YtxH PF12732.7 CDJ84695.1 - 0.3 11.6 1.2 0.49 11.0 1.2 1.3 1 0 0 1 1 1 0 YtxH-like protein SR-25 PF10500.9 CDJ84697.1 - 1.3 8.5 14.5 0.45 10.1 5.3 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SMAP PF15477.6 CDJ84698.1 - 9e-16 58.6 0.3 9e-16 58.6 0.3 2.9 2 1 0 2 2 2 1 Small acidic protein family DEAD PF00270.29 CDJ84700.1 - 3.8e-18 65.9 0.0 8.2e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ84700.1 - 4.9e-16 59.1 0.0 3e-14 53.3 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.10 CDJ84700.1 - 5.9e-16 58.3 0.1 1.3e-15 57.2 0.1 1.6 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 CDJ84700.1 - 2.3e-14 53.1 0.0 7.1e-14 51.5 0.0 1.9 1 0 0 1 1 1 1 HRDC domain RecQ_Zn_bind PF16124.5 CDJ84700.1 - 5.1e-14 52.8 2.3 5.1e-14 52.8 2.3 2.6 3 0 0 3 3 3 1 RecQ zinc-binding ResIII PF04851.15 CDJ84700.1 - 3.4e-05 23.9 0.0 6.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Protoglobin PF11563.8 CDJ84700.1 - 0.028 14.3 0.0 0.084 12.8 0.0 1.8 1 0 0 1 1 1 0 Protoglobin DUF934 PF06073.12 CDJ84700.1 - 0.14 12.0 0.2 0.45 10.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF934) Anillin PF08174.11 CDJ84701.1 - 8.4e-18 65.2 0.0 2.7e-17 63.5 0.0 2.0 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 CDJ84701.1 - 4.2e-06 27.2 0.0 1.6e-05 25.4 0.0 2.1 1 0 0 1 1 1 1 PH domain Spc110_C PF18520.1 CDJ84701.1 - 0.1 12.2 0.1 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 Spindle pole body component 110 C-terminal domain Anillin_N PF16018.5 CDJ84701.1 - 0.36 11.5 6.6 0.22 12.2 2.3 2.9 2 0 0 2 2 2 0 Anillin N-terminus Scramblase PF03803.15 CDJ84702.1 - 2.9e-67 226.2 0.0 3.5e-67 225.9 0.0 1.0 1 0 0 1 1 1 1 Scramblase DUF2243 PF10002.9 CDJ84702.1 - 0.0086 16.2 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2243) GSHPx PF00255.19 CDJ84703.1 - 7.5e-33 112.3 0.6 1e-32 111.9 0.6 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CDJ84703.1 - 0.0002 21.3 0.1 0.00033 20.6 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDJ84703.1 - 0.017 14.8 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Redoxin Motile_Sperm PF00635.26 CDJ84704.1 - 1.8e-05 24.5 0.0 3.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain UCH PF00443.29 CDJ84706.1 - 2.5e-45 155.0 0.1 5.7e-45 153.8 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ84706.1 - 2e-09 37.5 0.5 8.3e-09 35.5 0.5 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Syntaxin_2 PF14523.6 CDJ84706.1 - 0.087 13.2 0.3 2.6 8.5 0.1 3.0 3 0 0 3 3 3 0 Syntaxin-like protein Bin3 PF06859.12 CDJ84707.1 - 4.1e-41 140.0 0.0 7.8e-41 139.1 0.0 1.5 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.6 CDJ84707.1 - 1e-09 38.5 0.0 1.6e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ84707.1 - 1.4e-09 37.9 0.0 1.4e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ84707.1 - 2.9e-09 37.5 0.0 4.3e-06 27.3 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ84707.1 - 2.2e-08 34.8 0.0 1.1e-07 32.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ84707.1 - 8.9e-08 32.7 0.0 6.6e-06 26.7 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CDJ84707.1 - 1e-05 25.1 0.0 2.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CDJ84707.1 - 8.3e-05 22.2 0.0 0.0017 17.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.19 CDJ84707.1 - 0.00043 20.1 0.0 0.011 15.5 0.0 2.4 3 0 0 3 3 3 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 CDJ84707.1 - 0.0028 17.6 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CDJ84707.1 - 0.0048 16.4 0.0 0.022 14.2 0.0 1.9 1 1 0 2 2 2 1 Putative methyltransferase Methyltransf_32 PF13679.6 CDJ84707.1 - 0.0066 16.4 0.4 0.033 14.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 CDJ84707.1 - 0.015 14.6 0.0 3.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 CDJ84707.1 - 0.16 11.3 0.0 0.44 9.8 0.0 1.7 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family zf-C2H2_4 PF13894.6 CDJ84708.1 - 3.5e-08 33.6 21.2 0.091 13.6 0.2 6.8 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CDJ84708.1 - 5.5e-08 32.8 21.9 0.0026 18.1 0.2 6.6 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_3 PF13878.6 CDJ84708.1 - 0.022 14.6 5.1 0.61 10.0 0.1 3.9 4 0 0 4 4 4 0 zinc-finger of acetyl-transferase ESCO zf-H2C2_5 PF13909.6 CDJ84708.1 - 0.23 11.3 0.1 0.23 11.3 0.1 3.5 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 CDJ84708.1 - 0.26 11.6 3.1 10 6.5 0.0 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding CpXC PF14353.6 CDJ84708.1 - 0.27 11.3 6.0 14 5.7 0.0 4.2 2 1 3 5 5 5 0 CpXC protein zf-met PF12874.7 CDJ84708.1 - 0.42 11.1 0.1 0.42 11.1 0.1 4.6 4 1 0 4 4 4 0 Zinc-finger of C2H2 type Nudix_N_2 PF14803.6 CDJ84708.1 - 0.43 10.5 9.8 12 5.9 1.7 4.2 4 0 0 4 4 4 0 Nudix N-terminal zf_C2H2_ZHX PF18387.1 CDJ84708.1 - 0.48 10.1 12.9 0.78 9.4 0.4 3.8 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain FYVE PF01363.21 CDJ84708.1 - 2.1 8.5 7.9 4.3 7.5 4.7 2.9 2 1 0 2 2 2 0 FYVE zinc finger zf-Di19 PF05605.12 CDJ84708.1 - 7.9 6.9 20.7 0.5 10.7 0.3 5.0 5 1 1 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding Ion_trans PF00520.31 CDJ84709.1 - 6.2e-43 146.8 16.1 8e-43 146.4 16.1 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 CDJ84709.1 - 1.5e-29 102.2 0.5 2.7e-29 101.3 0.5 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 CDJ84709.1 - 4e-13 49.1 4.7 4e-13 49.1 4.7 2.7 3 0 0 3 3 3 1 Ion channel Lig_chan PF00060.26 CDJ84709.1 - 0.02 14.7 0.8 0.02 14.7 0.8 2.6 3 0 0 3 3 3 0 Ligand-gated ion channel BTB_3 PF16017.5 CDJ84709.1 - 0.039 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain DUF202 PF02656.15 CDJ84709.1 - 0.44 11.0 9.7 58 4.2 0.0 3.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) PKD_channel PF08016.12 CDJ84709.1 - 0.68 8.5 8.7 1.4 7.5 8.7 1.5 1 1 0 1 1 1 0 Polycystin cation channel UQ_con PF00179.26 CDJ84711.1 - 2.6e-23 82.2 0.1 5.1e-23 81.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CDJ84711.1 - 0.072 13.4 0.0 0.28 11.5 0.0 2.0 1 0 0 1 1 1 0 RWD domain UFC1 PF08694.11 CDJ84711.1 - 0.16 11.6 0.0 0.41 10.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Glutaredoxin PF00462.24 CDJ84712.1 - 5e-16 58.7 0.0 1.3e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin Selenoprotein_S PF06936.11 CDJ84712.1 - 1.4e-06 28.3 2.0 1.9e-06 27.8 2.0 1.3 1 0 0 1 1 1 1 Selenoprotein S (SelS) Thioredoxin_2 PF13098.6 CDJ84712.1 - 0.0002 21.8 0.9 0.00078 19.9 0.1 2.2 2 2 0 2 2 2 1 Thioredoxin-like domain DUF836 PF05768.14 CDJ84712.1 - 0.003 17.9 0.1 0.0075 16.7 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 CDJ84712.1 - 0.0037 17.3 0.1 0.015 15.3 0.0 2.1 2 1 0 2 2 2 1 Thioredoxin domain GST_N_3 PF13417.6 CDJ84712.1 - 0.009 16.4 0.0 0.027 14.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain FAM150 PF15129.6 CDJ84712.1 - 0.049 13.8 2.0 0.077 13.2 2.0 1.3 1 0 0 1 1 1 0 FAM150 family Thioredoxin PF00085.20 CDJ84712.1 - 0.11 12.4 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 CDJ84712.1 - 0.35 11.1 0.0 0.35 11.1 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like Surp PF01805.20 CDJ84713.1 - 7.4e-17 61.1 0.1 1.6e-16 60.0 0.1 1.6 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 CDJ84713.1 - 8.2e-12 44.8 0.0 1.9e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) cwf21 PF08312.12 CDJ84713.1 - 1.5e-07 31.4 6.6 1.5e-07 31.4 6.6 2.7 2 0 0 2 2 2 1 cwf21 domain CTK3 PF12243.8 CDJ84713.1 - 0.0018 18.2 0.1 0.0057 16.7 0.0 1.8 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 CTD_bind PF04818.13 CDJ84713.1 - 0.021 15.7 0.0 0.021 15.7 0.0 3.2 4 0 0 4 4 4 0 RNA polymerase II-binding domain. DNA_repr_REX1B PF14966.6 CDJ84713.1 - 0.57 10.9 4.1 2.8 8.6 0.9 3.4 3 1 1 4 4 4 0 DNA repair REX1-B SHMT PF00464.19 CDJ84714.1 - 1.4e-181 603.5 0.0 2.9e-179 595.8 0.0 2.0 1 1 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 CDJ84714.1 - 0.0037 16.6 0.0 0.014 14.7 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase DUF5437 PF17505.2 CDJ84715.1 - 0.95 9.5 3.1 1.7 8.7 3.1 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5437) Med15 PF09606.10 CDJ84716.1 - 4.6e-51 174.5 130.4 8.3e-25 87.6 0.3 4.0 1 1 3 4 4 4 3 ARC105 or Med15 subunit of Mediator complex non-fungal KIX_2 PF16987.5 CDJ84716.1 - 0.0029 17.5 0.0 0.0078 16.2 0.0 1.8 1 0 0 1 1 1 1 KIX domain KIX PF02172.16 CDJ84716.1 - 0.45 10.8 2.7 0.46 10.8 0.3 2.3 2 1 0 2 2 2 0 KIX domain DEAD PF00270.29 CDJ84717.1 - 1.8e-51 174.4 0.0 5.6e-51 172.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ84717.1 - 4.8e-27 94.5 0.0 2.2e-26 92.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ84717.1 - 0.00031 20.8 0.2 0.0015 18.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cpn60_TCP1 PF00118.24 CDJ84718.1 - 4.4e-159 530.2 2.8 4.9e-159 530.1 2.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF4073 PF13285.6 CDJ84718.1 - 0.17 11.6 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4073) Antimicrobial25 PF16839.5 CDJ84719.1 - 4.7e-25 87.4 15.3 6.3e-25 87.0 15.3 1.1 1 0 0 1 1 1 1 Nematode antimicrobial peptide Myticin-prepro PF10690.9 CDJ84719.1 - 0.86 9.9 15.6 2.8 8.2 15.6 1.8 1 1 0 1 1 1 0 Myticin pre-proprotein from the mussel Antimicrobial25 PF16839.5 CDJ84720.1 - 2e-24 85.4 14.3 2.7e-24 85.0 14.3 1.1 1 0 0 1 1 1 1 Nematode antimicrobial peptide Myticin-prepro PF10690.9 CDJ84720.1 - 7 7.0 14.9 28 5.0 14.9 1.8 1 1 0 1 1 1 0 Myticin pre-proprotein from the mussel Neur_chan_memb PF02932.16 CDJ84721.1 - 4.6e-60 203.6 0.3 6.4e-60 203.2 0.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CDJ84721.1 - 1e-54 185.3 3.0 1.6e-54 184.6 3.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF2207 PF09972.9 CDJ84721.1 - 0.13 11.0 3.8 0.48 9.1 3.9 1.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Flavi_NS4A PF01350.17 CDJ84721.1 - 0.8 9.6 9.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A Spo7 PF03907.13 CDJ84721.1 - 6 6.3 6.3 20 4.6 6.3 1.8 1 1 0 1 1 1 0 Spo7-like protein Antimicrobial25 PF16839.5 CDJ84722.1 - 2.2e-24 85.3 14.9 3.3e-24 84.7 14.9 1.3 1 0 0 1 1 1 1 Nematode antimicrobial peptide Myticin-prepro PF10690.9 CDJ84722.1 - 0.9 9.8 13.2 2.2 8.6 13.2 1.7 1 1 0 1 1 1 0 Myticin pre-proprotein from the mussel Antimicrobial25 PF16839.5 CDJ84723.1 - 1.9e-24 85.5 14.3 2.6e-24 85.1 14.3 1.2 1 0 0 1 1 1 1 Nematode antimicrobial peptide Myticin-prepro PF10690.9 CDJ84723.1 - 2.3 8.5 11.6 4.1 7.7 11.6 1.6 1 1 0 1 1 1 0 Myticin pre-proprotein from the mussel GTP_EFTU PF00009.27 CDJ84724.1 - 3.3e-48 163.8 0.1 5.9e-48 163.0 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CDJ84724.1 - 4.5e-15 55.4 0.0 1.5e-14 53.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 CDJ84724.1 - 6.2e-05 23.0 0.3 0.00035 20.6 0.1 2.4 4 0 0 4 4 4 1 Elongation Factor G, domain II EFG_IV PF03764.18 CDJ84724.1 - 0.0015 18.3 0.0 0.0078 16.0 0.0 2.3 1 1 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 CDJ84724.1 - 0.05 13.7 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF4089 PF13318.6 CDJ84725.1 - 0.059 13.8 0.5 0.12 12.9 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4089) Pkinase PF00069.25 CDJ84726.1 - 1.5e-54 185.2 0.0 1.8e-54 184.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ84726.1 - 8.8e-20 71.1 0.0 7.6e-19 68.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CDJ84726.1 - 7.4e-07 29.3 0.0 0.00035 20.6 0.0 2.9 3 0 0 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 CDJ84726.1 - 0.085 12.4 0.2 0.21 11.2 0.2 1.6 1 1 0 1 1 1 0 RIO1 family Ammonium_transp PF00909.21 CDJ84727.1 - 7.9e-111 370.6 15.3 9.4e-111 370.3 15.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family UPF0029 PF01205.19 CDJ84727.1 - 0.0076 16.6 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Peptidase_C2 PF00648.21 CDJ84728.1 - 3.5e-123 410.4 0.0 4.4e-123 410.0 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 CDJ84728.1 - 2.7e-39 134.6 0.0 4.3e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III Pyr_redox_3 PF13738.6 CDJ84729.1 - 1e-13 51.3 0.0 6.5e-12 45.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CDJ84729.1 - 2.1e-06 27.2 0.0 0.059 12.6 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CDJ84729.1 - 4.2e-05 22.9 1.0 0.00045 19.5 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 CDJ84729.1 - 0.00078 18.0 0.9 0.013 14.0 0.5 2.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.19 CDJ84729.1 - 0.017 14.4 0.3 0.031 13.5 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 CDJ84729.1 - 0.071 13.2 0.0 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 CDJ84729.1 - 0.18 11.4 0.3 0.58 9.7 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Mito_carr PF00153.27 CDJ84730.1 - 1.3e-47 159.6 7.5 3e-17 62.3 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Prefoldin_2 PF01920.20 CDJ84731.1 - 1.8e-11 43.9 7.5 2.3e-11 43.6 7.5 1.2 1 0 0 1 1 1 1 Prefoldin subunit KIP1 PF07765.12 CDJ84731.1 - 0.028 14.5 1.2 4.9 7.3 0.1 2.4 2 1 0 2 2 2 0 KIP1-like protein UDPGP PF01704.18 CDJ84732.1 - 1.7e-35 122.5 0.0 2.3e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 CDJ84732.1 - 0.0047 17.3 0.4 0.017 15.5 0.4 2.0 1 1 0 1 1 1 1 MobA-like NTP transferase domain T4_baseplate PF12322.8 CDJ84732.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 T4 bacteriophage base plate protein zf-C4 PF00105.18 CDJ84733.1 - 1.1e-27 96.3 14.9 1.1e-27 96.3 14.9 1.6 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ84733.1 - 0.024 14.2 0.5 0.08 12.5 0.5 1.8 1 1 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor V_ATPase_I PF01496.19 CDJ84734.1 - 2.3e-38 131.7 2.4 2.7e-38 131.5 2.4 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Occludin_ELL PF07303.13 CDJ84734.1 - 0.0062 17.2 3.9 1.1 10.0 0.7 2.3 2 0 0 2 2 2 2 Occludin homology domain Fib_alpha PF08702.10 CDJ84734.1 - 0.051 13.8 1.8 0.092 12.9 1.8 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FapA PF03961.13 CDJ84734.1 - 0.067 11.8 1.3 0.074 11.6 1.3 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A APG6_N PF17675.1 CDJ84734.1 - 0.18 12.3 7.4 0.28 11.7 7.4 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region G10 PF01125.17 CDJ84734.1 - 0.19 11.5 0.6 0.3 10.9 0.3 1.4 1 1 0 1 1 1 0 G10 protein DHR10 PF18595.1 CDJ84734.1 - 0.5 10.4 9.2 1.1 9.4 3.0 2.7 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain FlaC_arch PF05377.11 CDJ84734.1 - 0.69 10.3 4.4 2.2 8.7 1.4 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HDV_ag PF01517.18 CDJ84734.1 - 0.88 9.3 4.1 14 5.4 0.5 2.4 2 1 0 2 2 2 0 Hepatitis delta virus delta antigen YgaB PF14182.6 CDJ84734.1 - 4.9 7.6 11.3 5.2 7.5 0.2 2.9 3 0 0 3 3 3 0 YgaB-like protein TPK_catalytic PF04263.16 CDJ84735.1 - 6.6e-33 113.3 0.0 9.1e-33 112.9 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 CDJ84735.1 - 4.5e-17 61.5 0.0 6.6e-17 61.0 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Pyr_redox_2 PF07992.14 CDJ84736.1 - 7.3e-54 183.0 2.1 8.8e-54 182.7 2.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CDJ84736.1 - 2.1e-27 95.5 0.0 4.9e-27 94.4 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 CDJ84736.1 - 1.9e-15 56.9 2.9 3.6e-14 52.7 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDJ84736.1 - 3.4e-15 56.4 5.1 1.7e-12 47.7 0.1 3.1 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CDJ84736.1 - 3.3e-07 29.7 0.2 3.3e-07 29.7 0.2 1.8 2 1 1 3 3 3 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 CDJ84736.1 - 0.00024 20.6 2.0 0.016 14.5 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 CDJ84736.1 - 0.00036 19.4 6.9 0.13 11.0 3.8 3.1 2 1 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 CDJ84736.1 - 0.004 16.3 2.9 0.004 16.3 2.9 2.6 2 1 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.6 CDJ84736.1 - 0.0079 15.4 0.3 0.032 13.4 0.0 2.0 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 CDJ84736.1 - 0.019 14.5 11.0 0.46 10.0 0.1 3.1 2 1 0 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.17 CDJ84736.1 - 0.021 14.1 0.9 0.045 13.0 0.9 1.5 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 CDJ84736.1 - 0.35 10.1 3.1 4.2 6.6 0.2 2.9 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 CDJ84736.1 - 9.5 6.5 7.4 1 9.6 1.5 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain PSP PF04046.16 CDJ84737.1 - 2.1e-14 53.1 0.0 5.1e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 PSP zf-RING_6 PF14835.6 CDJ84738.1 - 0.031 14.1 1.1 11 5.9 0.1 3.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DNA_ligase_ZBD PF03119.16 CDJ84738.1 - 0.048 13.7 2.5 0.12 12.4 0.3 3.0 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Glyco_hydro_31 PF01055.26 CDJ84739.1 - 3.5e-131 438.4 2.4 4.4e-131 438.1 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CDJ84739.1 - 0.00013 22.2 0.0 0.00046 20.4 0.0 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like adh_short PF00106.25 CDJ84740.1 - 1.8e-39 135.2 0.0 2.2e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ84740.1 - 1.6e-26 93.3 0.0 2e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ84740.1 - 9.9e-13 48.4 0.0 1.6e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CDJ84740.1 - 0.0035 16.5 0.0 0.0044 16.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.18 CDJ84740.1 - 0.0069 16.6 0.1 0.011 15.9 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 CDJ84740.1 - 0.068 13.4 0.1 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 CDJ84740.1 - 0.12 11.8 0.1 0.25 10.8 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family YhzD PF14120.6 CDJ84741.1 - 5 7.3 5.7 56 3.9 0.5 3.4 2 1 1 3 3 3 0 YhzD-like protein DUF724 PF05266.14 CDJ84742.1 - 0.071 12.9 7.0 0.12 12.2 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) GDP_Man_Dehyd PF16363.5 CDJ84743.1 - 1.9e-44 152.4 0.0 1.9e-43 149.1 0.0 2.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CDJ84743.1 - 2.9e-40 138.2 0.0 7.1e-40 137.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CDJ84743.1 - 4.7e-09 35.8 0.3 1e-07 31.4 0.3 2.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 CDJ84743.1 - 1.3e-07 31.1 0.0 0.08 12.1 0.1 3.2 2 1 0 3 3 3 3 Male sterility protein 3Beta_HSD PF01073.19 CDJ84743.1 - 5.6e-07 28.9 0.0 0.00031 19.9 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CDJ84743.1 - 3.3e-06 26.4 0.0 1.3e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 CDJ84743.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 CDJ84743.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.25 CDJ84743.1 - 0.21 11.0 0.0 0.42 10.0 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.10 CDJ84743.1 - 0.23 11.3 0.0 0.4 10.6 0.0 1.3 1 0 0 1 1 1 0 KR domain MFS_1 PF07690.16 CDJ84744.1 - 3.1e-42 144.8 29.5 4e-41 141.1 29.6 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ84744.1 - 0.0011 17.9 32.3 0.02 13.7 32.3 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter Churchill PF06573.11 CDJ84745.1 - 0.011 16.0 0.3 0.033 14.5 0.1 1.9 1 1 0 1 1 1 0 Churchill protein Zn-ribbon_8 PF09723.10 CDJ84745.1 - 0.079 13.1 5.5 0.58 10.3 0.2 3.8 4 0 0 4 4 4 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 CDJ84745.1 - 0.32 11.5 2.6 0.94 10.0 0.0 2.6 3 0 0 3 3 3 0 Zinc-finger double domain OrfB_Zn_ribbon PF07282.11 CDJ84745.1 - 0.46 10.5 2.9 0.56 10.2 0.3 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain ADD_ATRX PF17981.1 CDJ84745.1 - 0.6 10.0 0.1 0.6 10.0 0.1 2.7 3 1 1 4 4 4 0 Cysteine Rich ADD domain zf-C2H2_4 PF13894.6 CDJ84745.1 - 0.98 10.4 12.9 1.7 9.7 0.7 3.4 4 0 0 4 4 4 0 C2H2-type zinc finger Globin PF00042.22 CDJ84746.1 - 1.5e-14 54.4 0.0 2e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Globin Glyco_transf_92 PF01697.27 CDJ84747.1 - 9.3e-18 64.8 0.0 1e-17 64.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 92 IlvC PF01450.19 CDJ84747.1 - 0.043 14.1 0.0 0.064 13.5 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF4632 PF15451.6 CDJ84749.1 - 0.29 11.2 1.8 0.46 10.6 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Gp-FAR-1 PF05823.12 CDJ84751.1 - 0.00089 19.6 0.1 0.0025 18.2 0.1 1.8 1 1 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) TAtT PF16811.5 CDJ84751.1 - 0.011 15.0 1.8 0.014 14.7 1.8 1.2 1 0 0 1 1 1 0 TRAP transporter T-component ShK PF01549.24 CDJ84752.1 - 3.7e-05 24.2 4.9 0.00013 22.4 4.9 2.0 1 1 0 1 1 1 1 ShK domain-like ShK PF01549.24 CDJ84753.1 - 3.9e-05 24.1 4.5 0.00011 22.6 4.5 1.9 1 1 0 1 1 1 1 ShK domain-like ShK PF01549.24 CDJ84754.1 - 2.1e-05 24.9 5.9 7.6e-05 23.2 5.9 2.0 1 1 0 1 1 1 1 ShK domain-like ShK PF01549.24 CDJ84755.1 - 4.6e-05 23.9 4.7 0.00011 22.6 4.7 1.8 1 1 0 1 1 1 1 ShK domain-like Gp-FAR-1 PF05823.12 CDJ84756.1 - 5.5e-10 39.8 0.2 1.3e-09 38.6 0.2 1.6 2 0 0 2 2 2 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF5343 PF17278.2 CDJ84756.1 - 0.016 15.3 1.0 0.95 9.5 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5343) PNPase PF03726.14 CDJ84756.1 - 0.11 13.0 1.1 0.5 10.9 0.1 2.2 2 1 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DDE_Tnp_1_7 PF13843.6 CDJ84760.1 - 1.8e-51 175.5 0.0 2.2e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 Glyco_hydro_47 PF01532.20 CDJ84761.1 - 1.7e-40 139.3 0.0 2.6e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Adeno_52K PF03052.15 CDJ84761.1 - 0.09 12.2 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Adenoviral protein L1 52/55-kDa LANC_like PF05147.13 CDJ84761.1 - 0.15 10.6 0.0 0.64 8.5 0.0 1.8 2 0 0 2 2 2 0 Lanthionine synthetase C-like protein Glyco_hydro_127 PF07944.12 CDJ84761.1 - 0.17 10.3 0.0 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 AAA_30 PF13604.6 CDJ84762.1 - 0.018 14.7 0.8 0.028 14.2 0.8 1.2 1 0 0 1 1 1 0 AAA domain Glyco_hydro_47 PF01532.20 CDJ84763.1 - 2.4e-11 43.2 0.0 3.4e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4185 PF13810.6 CDJ84763.1 - 0.022 14.0 0.0 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) ABC_membrane PF00664.23 CDJ84764.1 - 8.6e-36 124.0 11.6 1.2e-35 123.5 11.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region EF-hand_7 PF13499.6 CDJ84766.1 - 5.6e-16 58.7 5.4 4.3e-08 33.5 1.7 4.4 3 2 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 CDJ84766.1 - 1.4e-14 53.6 1.2 0.00031 20.5 0.0 5.4 5 1 0 5 5 5 4 EF-hand domain pair EF-hand_1 PF00036.32 CDJ84766.1 - 3.8e-12 44.9 15.3 0.0028 17.1 2.1 6.1 7 0 0 7 7 7 4 EF hand EF-hand_6 PF13405.6 CDJ84766.1 - 2.7e-11 42.5 8.7 0.0013 18.4 1.5 5.8 6 0 0 6 6 6 3 EF-hand domain EF-hand_5 PF13202.6 CDJ84766.1 - 2.3e-08 33.1 2.0 0.022 14.2 1.7 5.2 4 0 0 4 4 4 2 EF hand SNF2_N PF00176.23 CDJ84768.1 - 4.7e-23 81.5 0.4 1.2e-18 67.0 0.0 2.4 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ84768.1 - 7.8e-14 52.0 0.0 2.2e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HARP PF07443.13 CDJ84768.1 - 2e-09 36.9 0.0 5.1e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 HepA-related protein (HARP) ResIII PF04851.15 CDJ84768.1 - 0.0001 22.3 0.0 0.00053 20.0 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CDJ84768.1 - 0.0052 16.0 0.0 0.0097 15.1 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Flavi_DEAD PF07652.14 CDJ84768.1 - 0.014 15.4 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain Casc1_N PF15927.5 CDJ84768.1 - 0.69 9.6 5.4 1.5 8.5 4.5 1.9 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus Lectin_leg-like PF03388.13 CDJ84769.1 - 0.18 11.1 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Legume-like lectin family Beta-lactamase PF00144.24 CDJ84769.1 - 0.19 10.9 0.0 0.2 10.8 0.0 1.0 1 0 0 1 1 1 0 Beta-lactamase Beta-lactamase PF00144.24 CDJ84770.1 - 4.7e-36 124.7 0.0 6.1e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase DUF3169 PF11368.8 CDJ84772.1 - 0.011 15.3 0.2 0.012 15.2 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Adeno_E3_CR2 PF02439.15 CDJ84772.1 - 0.084 12.7 3.0 0.12 12.2 3.0 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 NDUF_B6 PF09782.9 CDJ84772.1 - 0.12 12.5 0.1 0.13 12.4 0.1 1.1 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit DUF948 PF06103.11 CDJ84772.1 - 0.21 11.8 5.1 1 9.7 0.7 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF496 PF04363.12 CDJ84773.1 - 0.12 12.5 2.1 0.49 10.4 2.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF496) Ins145_P3_rec PF08709.11 CDJ84774.1 - 4.1e-78 261.4 0.1 2.6e-77 258.8 0.1 2.3 2 0 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RYDR_ITPR PF01365.21 CDJ84774.1 - 7.4e-61 205.1 22.4 9.6e-53 178.6 2.4 4.8 4 1 0 4 4 4 3 RIH domain MIR PF02815.19 CDJ84774.1 - 1.7e-53 181.2 0.0 8.5e-50 169.2 0.0 2.9 2 0 0 2 2 2 2 MIR domain RIH_assoc PF08454.11 CDJ84774.1 - 6.3e-29 99.8 1.9 6.3e-29 99.8 1.9 6.3 7 1 0 7 7 7 1 RyR and IP3R Homology associated Ion_trans PF00520.31 CDJ84774.1 - 8.1e-20 71.1 0.2 3.9e-19 68.9 0.2 2.0 1 1 0 1 1 1 1 Ion transport protein Tn7_Tnp_TnsA_C PF08721.11 CDJ84774.1 - 0.014 16.1 0.4 0.17 12.6 0.1 3.2 2 0 0 2 2 2 0 TnsA endonuclease C terminal E3_UbLigase_EDD PF11547.8 CDJ84774.1 - 0.014 15.1 0.3 0.7 9.6 0.0 2.8 2 0 0 2 2 2 0 E3 ubiquitin ligase EDD PSD2 PF07624.11 CDJ84774.1 - 0.031 14.0 0.8 1.9 8.4 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) DUF4139 PF13598.6 CDJ84775.1 - 4.3e-53 180.1 0.0 8.8e-53 179.1 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4139) MRP-S24 PF14955.6 CDJ84775.1 - 1.7e-50 170.5 0.1 2.8e-50 169.8 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S24 DUF4140 PF13600.6 CDJ84775.1 - 1.3e-19 70.4 9.0 7e-19 68.1 1.2 2.5 2 0 0 2 2 2 2 N-terminal domain of unknown function (DUF4140) HAUS6_N PF14661.6 CDJ84775.1 - 0.052 13.1 0.5 0.12 11.9 0.3 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF4201 PF13870.6 CDJ84775.1 - 0.52 10.0 6.4 0.21 11.3 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) KxDL PF10241.9 CDJ84775.1 - 0.58 10.5 3.9 11 6.3 1.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein PhaP_Bmeg PF09602.10 CDJ84775.1 - 2.4 8.1 5.3 0.67 9.9 1.4 2.0 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) CC2-LZ PF16516.5 CDJ84775.1 - 2.5 8.5 6.4 2.2 8.7 0.5 2.4 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Swi5 PF07061.11 CDJ84775.1 - 3.9 7.6 6.0 5 7.3 0.5 2.4 2 0 0 2 2 2 0 Swi5 zf-C4 PF00105.18 CDJ84776.1 - 4.7e-24 84.6 12.2 4.7e-24 84.6 12.2 2.0 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ84776.1 - 1.2e-07 31.5 2.2 1.6e-07 31.1 1.0 1.8 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-RRPl_C4 PF17026.5 CDJ84776.1 - 0.033 14.3 5.0 0.081 13.0 5.0 1.6 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type CwsA PF10814.8 CDJ84777.1 - 0.035 14.3 0.0 0.038 14.2 0.0 1.1 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA Sre PF03125.18 CDJ84778.1 - 7.4e-10 38.5 0.4 7.9e-10 38.4 0.4 1.0 1 0 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor 7TM_GPCR_Srab PF10292.9 CDJ84778.1 - 0.0012 17.9 0.2 0.0012 17.9 0.2 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Srab PF10292.9 CDJ84779.1 - 7.1e-08 31.7 0.4 7.6e-08 31.6 0.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Srb PF02175.16 CDJ84779.1 - 0.0029 17.4 0.5 0.0034 17.2 0.5 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srb MARVEL PF01284.23 CDJ84779.1 - 0.01 15.9 4.5 0.014 15.4 4.5 1.3 1 1 0 1 1 1 0 Membrane-associating domain Erv26 PF04148.13 CDJ84779.1 - 0.032 14.1 1.4 0.052 13.4 1.4 1.3 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 7TM_GPCR_Sra PF02117.16 CDJ84779.1 - 0.036 12.9 0.3 0.042 12.7 0.3 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sra ACP_syn_III_C PF08541.10 CDJ84780.1 - 0.21 11.8 0.0 0.42 10.8 0.0 1.4 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FF PF01846.19 CDJ84781.1 - 1.4e-63 210.8 38.7 2.4e-14 53.2 3.5 6.6 6 0 0 6 6 6 6 FF domain WW PF00397.26 CDJ84781.1 - 5.2e-24 84.0 24.7 3.5e-08 33.4 1.3 3.9 3 0 0 3 3 3 3 WW domain RhoGAP-FF1 PF16512.5 CDJ84781.1 - 2.9e-05 24.6 19.0 0.0027 18.3 1.0 4.1 3 1 1 4 4 4 2 p190-A and -B Rho GAPs FF domain Alg6_Alg8 PF03155.15 CDJ84782.1 - 1.1e-136 456.6 42.5 1.5e-136 456.2 42.5 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Endonuclease_5 PF04493.14 CDJ84782.1 - 9e-38 129.9 0.0 1.7e-37 129.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease V Glyco_hydro_25 PF01183.20 CDJ84784.1 - 0.0004 20.6 0.1 0.00052 20.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Glyco_hydro_25 PF01183.20 CDJ84785.1 - 0.0061 16.8 0.3 0.0073 16.5 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Leuk-A4-hydro_C PF09127.11 CDJ84786.1 - 0.00041 20.4 0.2 1.1 9.3 0.0 2.3 2 0 0 2 2 2 2 Leukotriene A4 hydrolase, C-terminal PUD PF03714.14 CDJ84786.1 - 0.00045 21.0 3.4 0.55 11.1 0.2 2.4 2 0 0 2 2 2 2 Bacterial pullanase-associated domain Glyco_hydro_25 PF01183.20 CDJ84786.1 - 0.0015 18.7 5.9 0.013 15.7 0.4 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 25 DUF3678 PF12435.8 CDJ84786.1 - 0.25 10.8 4.1 3.2 7.2 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) DUF1906 PF08924.11 CDJ84787.1 - 0.013 15.6 0.3 0.015 15.4 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1906) Leuk-A4-hydro_C PF09127.11 CDJ84787.1 - 0.081 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal Glyco_hydro_25 PF01183.20 CDJ84788.1 - 5.7e-06 26.6 1.9 7.6e-06 26.2 1.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 GGGtGRT PF14057.6 CDJ84789.1 - 8.4e-31 107.1 0.7 9.1e-31 107.0 0.7 1.0 1 0 0 1 1 1 1 GGGtGRT protein SNF PF00209.18 CDJ84790.1 - 4.9e-82 276.3 40.7 1.7e-80 271.2 30.9 2.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family dsrm PF00035.26 CDJ84791.1 - 6.8e-34 116.4 1.3 2.9e-08 34.3 0.1 5.7 6 0 0 6 6 6 4 Double-stranded RNA binding motif Staufen_C PF16482.5 CDJ84791.1 - 3.3e-14 53.0 0.3 5.1e-09 36.3 0.0 4.3 5 0 0 5 5 5 2 Staufen C-terminal domain DND1_DSRM PF14709.7 CDJ84791.1 - 2.3e-05 24.6 9.1 1 9.7 0.4 6.2 5 2 0 5 5 5 3 double strand RNA binding domain from DEAD END PROTEIN 1 HMG_box PF00505.19 CDJ84792.1 - 3.2e-17 62.7 1.6 3.2e-17 62.7 1.6 3.5 4 0 0 4 4 4 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ84792.1 - 3.4e-06 27.6 1.0 3.4e-06 27.6 1.0 2.7 2 1 0 2 2 2 1 HMG-box domain Prominin PF05478.11 CDJ84792.1 - 0.31 8.9 2.0 0.48 8.3 2.0 1.3 1 0 0 1 1 1 0 Prominin DFP PF04127.15 CDJ84793.1 - 5.1e-05 23.2 0.0 6.4e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein C2 PF00168.30 CDJ84794.1 - 0.093 13.0 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 C2 domain RGS PF00615.19 CDJ84796.1 - 5.5e-49 165.3 2.2 2.1e-26 92.5 0.0 2.0 2 0 0 2 2 2 2 Regulator of G protein signaling domain T3SS_needle_F PF09392.10 CDJ84796.1 - 0.0083 16.3 0.1 0.016 15.4 0.1 1.4 1 0 0 1 1 1 1 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF WD40 PF00400.32 CDJ84797.1 - 7.4e-12 45.6 7.1 5.6e-05 23.8 0.6 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ84797.1 - 1.6e-10 41.1 0.1 0.015 15.6 0.0 3.6 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDJ84797.1 - 7.2e-05 22.8 0.2 0.00042 20.2 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CDJ84797.1 - 0.01 15.2 0.0 0.19 11.0 0.1 2.1 2 0 0 2 2 2 0 WD40-like domain Ig_4 PF16680.5 CDJ84797.1 - 0.031 14.5 0.1 0.078 13.2 0.1 1.6 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain PQQ_3 PF13570.6 CDJ84797.1 - 0.032 14.7 1.5 18 6.0 0.1 3.4 4 0 0 4 4 4 0 PQQ-like domain ELYS-bb PF16687.5 CDJ84797.1 - 0.063 11.9 0.0 0.12 10.9 0.0 1.5 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin SdiA-regulated PF06977.11 CDJ84797.1 - 0.078 12.2 0.0 0.27 10.4 0.0 1.7 2 0 0 2 2 2 0 SdiA-regulated DUF1768 PF08719.11 CDJ84798.1 - 5.2e-17 62.5 0.1 1.4e-16 61.2 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1768) Astacin PF01400.24 CDJ84799.1 - 9.9e-34 116.6 0.1 1.6e-33 116.0 0.1 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) ShK PF01549.24 CDJ84799.1 - 9.2e-05 22.9 2.6 0.00029 21.3 2.6 1.9 1 0 0 1 1 1 1 ShK domain-like Peptidase_M66 PF10462.9 CDJ84799.1 - 0.0032 16.5 0.0 0.0045 16.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_4 PF13583.6 CDJ84799.1 - 0.0084 15.8 0.1 0.015 14.9 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CDJ84799.1 - 0.018 14.9 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_5 PF13688.6 CDJ84799.1 - 0.048 13.8 0.1 0.087 13.0 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 SOG2 PF10428.9 CDJ84799.1 - 0.19 10.9 0.1 0.23 10.6 0.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Reprolysin_3 PF13582.6 CDJ84799.1 - 0.29 11.6 2.2 0.44 11.1 1.0 1.9 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like ShK PF01549.24 CDJ84800.1 - 1.8e-06 28.4 4.5 4.3e-06 27.2 4.5 1.7 1 0 0 1 1 1 1 ShK domain-like Astacin PF01400.24 CDJ84801.1 - 8.5e-27 94.0 0.0 1.6e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 CDJ84801.1 - 0.00095 19.7 0.1 0.0058 17.1 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CDJ84801.1 - 0.0019 17.9 0.2 0.0034 17.1 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 CDJ84801.1 - 0.0067 15.4 0.1 0.014 14.3 0.0 1.5 2 0 0 2 2 2 1 Peptidase M66 Peptidase_M10 PF00413.24 CDJ84801.1 - 0.03 14.2 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Matrixin Reprolysin_5 PF13688.6 CDJ84801.1 - 0.041 14.0 0.0 0.065 13.4 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 SOG2 PF10428.9 CDJ84801.1 - 0.075 12.2 0.2 0.1 11.8 0.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Astacin PF01400.24 CDJ84802.1 - 2.7e-37 128.3 0.0 4.3e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 CDJ84802.1 - 3.6e-06 26.9 0.2 0.0098 15.7 0.0 2.3 2 0 0 2 2 2 2 Matrixin Reprolysin_4 PF13583.6 CDJ84802.1 - 0.002 17.8 0.8 0.0034 17.0 0.4 1.6 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 CDJ84802.1 - 0.0024 16.9 0.1 0.0041 16.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_5 PF13688.6 CDJ84802.1 - 0.012 15.8 2.8 0.12 12.5 1.0 2.1 1 1 1 2 2 2 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CDJ84802.1 - 0.043 14.3 3.2 0.11 13.1 0.9 2.3 1 1 1 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 CDJ84802.1 - 0.049 12.2 0.1 0.081 11.5 0.1 1.3 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M8 PF01457.16 CDJ84802.1 - 0.088 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Leishmanolysin Ribul_P_3_epim PF00834.19 CDJ84802.1 - 0.13 11.6 0.0 6.2 6.1 0.0 2.1 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family Peptidase_M57 PF12388.8 CDJ84802.1 - 0.21 11.2 2.3 2.3 7.8 0.7 2.3 1 1 1 2 2 2 0 Dual-action HEIGH metallo-peptidase ADIP PF11559.8 CDJ84803.1 - 0.00064 19.8 8.5 0.00064 19.8 8.5 3.6 2 1 2 4 4 4 1 Afadin- and alpha -actinin-Binding TolA_bind_tri PF16331.5 CDJ84803.1 - 0.037 14.1 19.7 0.12 12.5 0.9 4.0 3 0 0 3 3 3 0 TolA binding protein trimerisation DUF812 PF05667.11 CDJ84803.1 - 0.092 11.6 34.7 0.024 13.5 29.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF812) TrmE_N PF10396.9 CDJ84803.1 - 0.16 12.3 0.0 0.45 10.8 0.0 1.8 1 0 0 1 1 1 0 GTP-binding protein TrmE N-terminus Lectin_N PF03954.14 CDJ84803.1 - 0.72 9.6 9.6 1.2 8.9 1.5 2.8 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain Baculo_PEP_C PF04513.12 CDJ84803.1 - 6.6 6.8 8.3 15 5.7 6.0 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-C2H2_4 PF13894.6 CDJ84804.1 - 3.6e-13 49.1 54.1 0.0028 18.4 1.5 8.1 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2 PF00096.26 CDJ84804.1 - 1.8e-10 40.7 61.9 0.021 15.3 2.0 7.8 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ84804.1 - 1.4e-06 28.4 57.5 0.07 13.6 0.8 8.8 9 0 0 9 9 9 4 Zinc-finger double domain zf-met PF12874.7 CDJ84804.1 - 0.00012 22.3 29.3 0.017 15.5 0.2 6.4 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-Di19 PF05605.12 CDJ84804.1 - 0.0045 17.3 39.7 0.16 12.3 8.7 5.3 3 1 3 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 CDJ84804.1 - 0.0069 16.7 37.4 0.0083 16.4 0.2 6.1 2 1 4 6 6 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 CDJ84804.1 - 0.008 16.9 0.3 0.008 16.9 0.3 4.3 3 1 1 4 4 4 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 CDJ84804.1 - 0.018 15.0 40.9 1.9 8.6 0.5 7.2 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ84804.1 - 0.019 15.3 0.9 0.019 15.3 0.9 6.5 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 CDJ84804.1 - 0.3 10.9 13.4 2 8.3 0.1 4.6 5 1 0 5 5 5 0 C2H2 type zinc-finger (1 copy) AKAP2_C PF15304.6 CDJ84804.1 - 0.43 9.8 2.7 0.76 9.0 2.7 1.3 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus Ribosomal_S26e PF01283.19 CDJ84804.1 - 4.1 7.9 11.0 5.3 7.5 1.9 3.3 3 1 0 3 3 3 0 Ribosomal protein S26e zf-C2H2_11 PF16622.5 CDJ84804.1 - 9.5 6.1 29.2 0.69 9.7 0.2 5.7 6 0 0 6 6 5 0 zinc-finger C2H2-type zf-C2H2 PF00096.26 CDJ84807.1 - 2.6e-22 78.0 44.6 1.7e-06 28.1 2.4 5.9 5 1 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ84807.1 - 1.4e-18 66.3 46.4 1.2e-07 31.8 2.1 6.6 6 1 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDJ84807.1 - 5.1e-16 58.0 41.4 0.00048 20.7 1.1 5.7 5 1 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDJ84807.1 - 0.00064 19.7 41.1 0.22 11.6 1.0 5.6 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CDJ84807.1 - 0.00064 19.4 18.9 0.26 11.1 0.9 4.6 4 0 0 4 4 4 3 zinc-finger C2H2-type zf-Di19 PF05605.12 CDJ84807.1 - 0.0012 19.1 24.1 0.058 13.7 9.7 4.4 3 2 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 CDJ84807.1 - 0.0021 18.3 16.7 0.0043 17.3 10.5 2.7 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 CDJ84807.1 - 0.029 14.7 28.0 1.2 9.5 0.6 4.9 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CDJ84807.1 - 0.12 12.7 28.4 1.1 9.7 0.8 5.2 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 CDJ84807.1 - 0.61 10.1 0.0 0.61 10.1 0.0 4.5 5 0 0 5 5 4 0 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 CDJ84807.1 - 0.91 10.3 16.7 0.39 11.5 4.5 2.9 1 1 1 2 2 2 0 zinc-ribbon family zf-C2H2_9 PF16293.5 CDJ84807.1 - 0.97 9.3 13.5 1.4 8.8 0.1 4.5 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-CHCC PF10276.9 CDJ84807.1 - 3.7 7.7 11.5 1.7 8.8 0.2 3.6 4 0 0 4 4 4 0 Zinc-finger domain zf-C2HE PF16278.5 CDJ84807.1 - 5.6 7.5 30.4 0.34 11.4 1.0 4.8 2 1 3 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger Pro_isomerase PF00160.21 CDJ84808.1 - 1.8e-40 138.8 0.1 4.6e-40 137.5 0.1 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Strep_SA_rep PF06696.11 CDJ84808.1 - 0.52 10.4 6.2 0.91 9.6 2.1 2.9 3 0 0 3 3 3 0 Streptococcal surface antigen repeat TIM PF00121.18 CDJ84809.1 - 8.7e-92 306.9 0.0 1e-91 306.7 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Phage_T4_Gp30_7 PF06919.11 CDJ84809.1 - 0.0011 19.1 0.1 0.01 16.0 0.0 2.2 2 0 0 2 2 2 1 Phage Gp30.7 protein BcrAD_BadFG PF01869.20 CDJ84810.1 - 6.8e-17 61.8 0.5 1e-16 61.2 0.5 1.3 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family NAPRTase_C PF17956.1 CDJ84811.1 - 1.1e-39 135.3 0.1 1.9e-39 134.5 0.1 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase_N PF17767.1 CDJ84811.1 - 8.2e-37 126.4 0.0 2.1e-36 125.0 0.0 1.8 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase PF04095.16 CDJ84811.1 - 3.1e-10 40.1 0.0 2.1e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family QRPTase_N PF02749.16 CDJ84811.1 - 0.027 14.5 0.0 0.059 13.4 0.0 1.6 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain MIF PF01187.18 CDJ84812.1 - 2.3e-36 124.6 0.0 3.5e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) LSM PF01423.22 CDJ84812.1 - 4e-17 61.7 0.1 7.9e-17 60.7 0.1 1.5 1 0 0 1 1 1 1 LSM domain Tautomerase PF01361.21 CDJ84812.1 - 0.0002 21.2 0.0 0.72 9.8 0.0 2.4 2 0 0 2 2 2 2 Tautomerase enzyme Hfq PF17209.3 CDJ84812.1 - 0.0081 15.8 0.1 0.03 14.0 0.1 1.9 2 0 0 2 2 2 1 Hfq protein Glyco_hydro_47 PF01532.20 CDJ84813.1 - 3.1e-138 461.5 0.3 3.6e-138 461.3 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 His_Phos_1 PF00300.22 CDJ84814.1 - 0.0091 15.7 0.0 0.024 14.4 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Cyclin_N PF00134.23 CDJ84816.1 - 1.1e-11 44.5 0.2 3e-08 33.4 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 CDJ84816.1 - 3e-05 24.1 0.2 0.00072 19.6 0.2 2.5 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.19 CDJ84816.1 - 0.0003 20.8 0.0 0.92 9.6 0.0 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat UTP15_C PF09384.10 CDJ84816.1 - 0.017 14.8 0.4 0.035 13.8 0.4 1.5 1 0 0 1 1 1 0 UTP15 C terminal Cyclin_C_2 PF16899.5 CDJ84816.1 - 0.042 14.2 0.0 0.13 12.7 0.0 1.9 1 1 0 1 1 1 0 Cyclin C-terminal domain SRP-alpha_N PF04086.13 CDJ84816.1 - 0.51 10.2 24.0 0.89 9.4 24.0 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal UCR_hinge PF02320.16 CDJ84817.1 - 5.6e-19 68.1 3.8 6.7e-19 67.9 3.8 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Ax_dynein_light PF10211.9 CDJ84817.1 - 0.048 13.6 0.5 0.053 13.5 0.5 1.0 1 0 0 1 1 1 0 Axonemal dynein light chain TBCA PF02970.16 CDJ84817.1 - 0.12 12.8 0.2 0.19 12.1 0.2 1.5 1 1 0 1 1 1 0 Tubulin binding cofactor A Ground-like PF04155.18 CDJ84818.1 - 2.6e-16 60.0 0.6 5e-16 59.1 0.6 1.5 1 0 0 1 1 1 1 Ground-like domain 7TM_GPCR_Srx PF10328.9 CDJ84819.1 - 5.6e-06 26.2 26.9 1.3e-05 25.0 26.9 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2633 PF11119.8 CDJ84819.1 - 0.04 13.8 3.9 0.42 10.6 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) Na_H_antiporter PF03553.14 CDJ84819.1 - 0.26 10.5 11.9 0.33 10.1 0.4 2.2 2 0 0 2 2 2 0 Na+/H+ antiporter family COX6A PF02046.15 CDJ84820.1 - 5.2e-20 72.0 1.2 6.7e-20 71.6 1.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa STAG PF08514.11 CDJ84821.1 - 1.2e-28 99.3 4.8 2.3e-28 98.4 0.2 3.3 3 0 0 3 3 3 1 STAG domain YyzF PF14116.6 CDJ84821.1 - 0.02 14.9 0.1 0.21 11.6 0.0 2.6 2 0 0 2 2 2 0 YyzF-like protein COX6A PF02046.15 CDJ84822.1 - 4.2e-20 72.3 0.2 5.2e-20 72.0 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Carb_anhydrase PF00194.21 CDJ84825.1 - 5e-61 206.5 0.0 5.9e-61 206.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF3750 PF12570.8 CDJ84825.1 - 0.04 14.6 0.8 3 8.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3750) Glyco_hydro_31 PF01055.26 CDJ84826.1 - 1.5e-138 462.7 4.8 2.1e-138 462.2 4.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 CDJ84826.1 - 1.4e-09 38.2 0.1 3.2e-09 37.0 0.1 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 CDJ84826.1 - 6.1e-07 29.7 0.2 2.1e-06 27.9 0.2 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like SANTA PF09133.10 CDJ84827.1 - 6.1e-35 119.6 0.0 1.2e-18 67.3 0.0 2.6 2 0 0 2 2 2 2 SANTA (SANT Associated) GlyL_C PF12524.8 CDJ84827.1 - 0.26 11.5 2.3 8.3 6.6 0.2 3.9 3 0 0 3 3 3 0 dsDNA virus glycoprotein L C terminal Proteasome PF00227.26 CDJ84828.1 - 7.1e-42 143.1 0.0 8e-42 142.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit ASC PF00858.24 CDJ84829.1 - 1.6e-50 172.4 3.7 2.4e-50 171.8 3.7 1.3 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Peptidase_C48 PF02902.19 CDJ84829.1 - 8.6e-36 123.8 0.3 1.6e-35 122.9 0.3 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Sema PF01403.19 CDJ84830.1 - 3.4e-56 190.9 0.0 5e-56 190.3 0.0 1.3 1 0 0 1 1 1 1 Sema domain TIG PF01833.24 CDJ84830.1 - 4.2e-30 103.7 0.0 4.3e-08 33.1 0.0 5.6 5 0 0 5 5 5 4 IPT/TIG domain TIG_plexin PF17960.1 CDJ84830.1 - 3.6e-24 84.6 0.1 5.6e-20 71.1 0.0 3.3 2 0 0 2 2 2 2 TIG domain TIG_2 PF18020.1 CDJ84830.1 - 4.9e-21 75.2 0.0 4.1e-20 72.2 0.0 2.6 3 0 0 3 3 3 1 TIG domain found in plexin PSI PF01437.25 CDJ84830.1 - 1.9e-17 63.5 49.7 3.7e-07 30.6 10.3 3.7 3 0 0 3 3 3 3 Plexin repeat Qn_am_d_aIII PF09099.10 CDJ84830.1 - 0.08 13.3 0.0 25 5.3 0.0 3.2 3 0 0 3 3 3 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III Kinesin PF00225.23 CDJ84831.1 - 1.7e-118 395.3 0.1 1.7e-118 395.3 0.1 1.9 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ84831.1 - 3.4e-26 92.0 0.6 9.1e-26 90.6 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding eIF3_N PF09440.10 CDJ84831.1 - 0.0018 18.7 11.7 0.0034 17.8 10.5 2.1 1 1 0 1 1 1 1 eIF3 subunit 6 N terminal domain Kinesin_assoc PF16183.5 CDJ84831.1 - 0.026 14.7 6.1 0.14 12.3 5.9 2.3 1 1 0 1 1 1 0 Kinesin-associated PIF1 PF05970.14 CDJ84831.1 - 0.068 12.3 0.1 0.14 11.3 0.1 1.4 1 0 0 1 1 1 0 PIF1-like helicase Nbs1_C PF08599.10 CDJ84831.1 - 0.093 12.9 7.3 0.022 14.9 2.8 2.3 1 1 1 2 2 2 0 DNA damage repair protein Nbs1 AAA_16 PF13191.6 CDJ84831.1 - 0.18 12.1 0.0 0.18 12.1 0.0 3.2 2 1 0 2 2 2 0 AAA ATPase domain Spc7 PF08317.11 CDJ84831.1 - 5.9 5.7 27.9 16 4.3 27.9 1.7 1 0 0 1 1 1 0 Spc7 kinetochore protein PK PF00224.21 CDJ84832.1 - 1.4e-153 510.9 1.2 1.8e-153 510.5 1.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CDJ84832.1 - 1.8e-30 105.6 0.0 6.8e-30 103.7 0.0 2.0 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CDJ84832.1 - 0.00043 19.5 1.0 0.0012 18.0 1.1 1.8 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF3479 PF11965.8 CDJ84832.1 - 0.18 11.9 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) DDE_3 PF13358.6 CDJ84833.1 - 7.2e-05 22.6 0.1 0.00011 22.0 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Transposase_1 PF01359.18 CDJ84833.1 - 0.0063 16.3 0.2 0.011 15.5 0.2 1.4 1 0 0 1 1 1 1 Transposase (partial DDE domain) RGS PF00615.19 CDJ84833.1 - 0.041 14.2 0.1 0.062 13.6 0.1 1.3 1 0 0 1 1 1 0 Regulator of G protein signaling domain SPATA1_C PF15743.5 CDJ84834.1 - 0.0029 17.7 1.9 0.0029 17.7 1.9 2.1 1 1 0 2 2 2 1 Spermatogenesis-associated C-terminus UPF0054 PF02130.17 CDJ84834.1 - 0.0065 16.3 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 PRKG1_interact PF15898.5 CDJ84834.1 - 0.011 16.6 8.5 0.16 12.8 2.2 2.2 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain TMF_TATA_bd PF12325.8 CDJ84834.1 - 0.013 15.7 1.5 0.013 15.7 1.5 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding LRS4 PF10422.9 CDJ84834.1 - 0.032 13.8 0.0 0.04 13.5 0.0 1.3 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 Fez1 PF06818.15 CDJ84834.1 - 0.04 14.4 6.1 0.043 14.3 1.7 2.0 2 0 0 2 2 2 0 Fez1 CENP-H PF05837.12 CDJ84834.1 - 0.38 11.2 5.8 9.6 6.7 2.0 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) SLATT_1 PF18181.1 CDJ84834.1 - 3.4 7.6 5.3 0.5 10.3 0.4 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Glyco_transf_64 PF09258.10 CDJ84835.1 - 0.0033 16.7 0.1 2.1 7.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 64 domain CARD_2 PF16739.5 CDJ84835.1 - 0.0047 16.9 0.0 0.02 14.9 0.0 2.1 1 0 0 1 1 1 1 Caspase recruitment domain DUF4533 PF15047.6 CDJ84835.1 - 0.019 14.5 1.4 3.9 7.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4533) CutA1 PF03091.15 CDJ84835.1 - 0.047 13.6 0.8 9.2 6.2 0.0 2.9 3 0 0 3 3 3 0 CutA1 divalent ion tolerance protein DUF3836 PF12930.7 CDJ84835.1 - 0.13 12.0 0.4 17 5.2 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF3836) DUF5555 PF17710.1 CDJ84835.1 - 0.26 10.8 0.0 19 4.7 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5555) Spc7 PF08317.11 CDJ84836.1 - 4.4e-06 25.8 62.2 0.0062 15.5 10.6 3.2 1 1 2 3 3 3 3 Spc7 kinetochore protein KASH_CCD PF14662.6 CDJ84836.1 - 0.00054 19.8 20.9 0.00054 19.8 20.9 3.5 1 1 2 3 3 2 1 Coiled-coil region of CCDC155 or KASH Seryl_tRNA_N PF02403.22 CDJ84836.1 - 0.06 13.6 52.3 0.32 11.2 5.9 5.4 2 1 4 6 6 6 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.12 CDJ84836.1 - 0.075 13.1 64.7 0.094 12.8 2.8 6.1 2 1 4 6 6 6 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 CDJ84836.1 - 0.25 11.8 75.7 0.69 10.4 11.5 5.3 1 1 4 5 5 5 0 Apg6 coiled-coil region DUF724 PF05266.14 CDJ84836.1 - 1.1 9.1 53.2 0.021 14.6 14.0 4.4 1 1 3 4 4 4 0 Protein of unknown function (DUF724) CENP-F_leu_zip PF10473.9 CDJ84836.1 - 1.4 8.9 67.6 0.33 11.0 1.9 5.0 2 1 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 CDJ84836.1 - 1.5 8.9 42.0 0.042 13.9 5.1 4.8 1 1 4 5 5 5 0 Laminin Domain II Atg14 PF10186.9 CDJ84836.1 - 1.9 7.5 48.5 0.55 9.3 13.5 3.6 1 1 3 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 DASH_Dad1 PF08649.10 CDJ84836.1 - 3.4 7.9 15.8 4.1 7.7 0.1 4.8 3 1 1 4 4 4 0 DASH complex subunit Dad1 TolA_bind_tri PF16331.5 CDJ84836.1 - 3.7 7.7 42.4 0.16 12.1 6.5 5.4 4 1 1 5 5 5 0 TolA binding protein trimerisation AAA_13 PF13166.6 CDJ84836.1 - 4.9 5.7 50.7 10 4.6 18.9 2.5 1 1 1 2 2 2 0 AAA domain DUF3584 PF12128.8 CDJ84836.1 - 5.4 4.4 52.1 0.2 9.1 31.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) APG17 PF04108.12 CDJ84836.1 - 5.6 6.0 42.8 1.2 8.2 8.6 3.6 1 1 2 3 3 3 0 Autophagy protein Apg17 Turandot PF07240.11 CDJ84836.1 - 7.6 6.6 7.4 1.4 8.9 0.2 3.4 3 2 0 3 3 3 0 Stress-inducible humoral factor Turandot FPP PF05911.11 CDJ84836.1 - 9.2 4.3 56.3 0.2 9.8 15.5 2.8 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil FUSC PF04632.12 CDJ84836.1 - 9.3 4.6 18.8 1.3 7.4 9.6 2.1 1 1 0 2 2 2 0 Fusaric acid resistance protein family YojJ PF10372.9 CDJ84836.1 - 9.9 6.3 24.7 0.59 10.3 1.7 5.6 4 1 1 5 5 5 0 Bacterial membrane-spanning protein N-terminus Mcl1_mid PF12341.8 CDJ84838.1 - 0.0035 16.7 0.0 0.0098 15.3 0.0 1.7 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region Coatomer_WDAD PF04053.14 CDJ84838.1 - 0.016 14.3 0.9 0.44 9.5 0.4 2.5 2 1 0 2 2 2 0 Coatomer WD associated region Hira PF07569.11 CDJ84838.1 - 0.026 14.2 0.0 0.32 10.7 0.0 2.4 2 0 0 2 2 2 0 TUP1-like enhancer of split RPN7 PF10602.9 CDJ84838.1 - 0.065 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN7 SET PF00856.28 CDJ84839.1 - 1.8e-12 48.0 0.0 6.6e-12 46.1 0.0 2.0 2 0 0 2 2 2 1 SET domain Pre-SET PF05033.16 CDJ84839.1 - 2.1e-06 28.4 12.6 2.1e-06 28.4 12.6 2.6 2 1 0 2 2 2 1 Pre-SET motif PAP_central PF04928.17 CDJ84841.1 - 6.7e-105 349.5 0.0 9.4e-105 349.0 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CDJ84841.1 - 1.5e-26 93.1 0.0 3e-18 66.0 0.0 2.6 2 0 0 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CDJ84841.1 - 5e-11 42.8 0.0 9.8e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain CBFD_NFYB_HMF PF00808.23 CDJ84842.1 - 2.9e-05 24.3 0.0 4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RhoGAP PF00620.27 CDJ84843.1 - 1.2e-29 103.2 0.0 2.4e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Albumin_I PF08027.11 CDJ84846.1 - 0.029 14.0 0.2 0.082 12.5 0.2 1.8 1 0 0 1 1 1 0 Albumin I chain b Forkhead_N PF08430.12 CDJ84847.1 - 9.2 6.9 34.8 1.7 9.3 30.7 1.7 1 1 1 2 2 2 0 Forkhead N-terminal region EF-hand_7 PF13499.6 CDJ84848.1 - 3.6e-09 36.9 2.8 6e-09 36.2 1.5 1.9 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CDJ84848.1 - 9.4e-06 24.9 2.0 0.01 15.3 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_1 PF00036.32 CDJ84848.1 - 1.1e-05 24.6 0.3 0.019 14.5 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDJ84848.1 - 0.00034 20.4 0.8 0.1 12.4 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ84848.1 - 0.0018 18.1 2.7 2.3 8.4 0.2 3.1 3 1 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CDJ84849.1 - 6.4e-10 39.3 2.6 9.9e-10 38.7 2.6 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CDJ84849.1 - 1.4e-06 27.4 2.3 0.0001 21.6 0.3 2.8 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 CDJ84849.1 - 7.8e-06 25.2 0.4 0.00096 18.5 0.1 2.9 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 CDJ84849.1 - 1.8e-05 24.3 3.6 0.067 13.2 0.1 2.8 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CDJ84849.1 - 0.0026 17.6 1.8 0.03 14.2 0.6 2.4 2 1 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ84849.1 - 0.073 13.4 1.6 2.7 8.3 1.6 2.1 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region FYVE PF01363.21 CDJ84850.1 - 5.4e-06 26.4 11.3 9.7e-06 25.6 11.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-4CXXC_R1 PF10497.9 CDJ84850.1 - 0.014 15.6 6.0 0.027 14.7 6.0 1.4 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 FYVE_2 PF02318.16 CDJ84850.1 - 0.028 14.6 7.2 0.068 13.4 7.2 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_5 PF14634.6 CDJ84850.1 - 1.7 8.7 11.7 18 5.4 11.7 2.3 1 1 0 1 1 1 0 zinc-RING finger domain Img2 PF05046.14 CDJ84851.1 - 2.1e-17 63.2 0.0 3.5e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) DUF2043 PF09740.9 CDJ84852.1 - 3.6e-51 172.3 1.8 2.3e-30 105.4 0.0 3.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2043) DUF4806 PF16064.5 CDJ84852.1 - 0.0049 17.1 6.3 0.52 10.6 0.2 3.9 4 0 0 4 4 4 2 Domain of unknown function (DUF4806) DUF884 PF05959.11 CDJ84852.1 - 0.034 13.8 0.1 11 5.6 0.0 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF884) DUF4777 PF16007.5 CDJ84852.1 - 0.05 13.9 0.5 0.62 10.4 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) Phage_pRha PF09669.10 CDJ84852.1 - 0.06 13.9 2.9 16 6.1 0.0 3.8 3 0 0 3 3 3 0 Phage regulatory protein Rha (Phage_pRha) Sec5 PF15469.6 CDJ84852.1 - 0.14 12.0 11.0 0.3 10.9 0.1 3.6 5 0 0 5 5 5 0 Exocyst complex component Sec5 CM_2 PF01817.21 CDJ84852.1 - 0.26 11.6 3.7 0.96 9.9 0.1 3.6 3 0 0 3 3 3 0 Chorismate mutase type II KH_1 PF00013.29 CDJ84855.1 - 5.8e-25 86.9 14.3 2.1e-14 53.1 0.4 3.5 3 1 0 3 3 3 2 KH domain KH_2 PF07650.17 CDJ84855.1 - 3.8e-07 29.8 3.0 0.0037 17.0 0.1 2.6 2 1 0 2 2 2 2 KH domain SLS PF14611.6 CDJ84855.1 - 0.00026 20.9 5.1 0.0021 17.9 0.5 2.2 1 1 1 2 2 2 2 Mitochondrial inner-membrane-bound regulator MOEP19 PF16005.5 CDJ84855.1 - 0.00056 19.9 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 2 KH-like RNA-binding domain KH_5 PF13184.6 CDJ84855.1 - 0.0025 17.9 1.1 1.1 9.3 0.2 2.5 2 0 0 2 2 2 2 NusA-like KH domain KH_4 PF13083.6 CDJ84855.1 - 0.0026 17.6 1.0 1.9 8.4 0.1 2.9 2 1 0 2 2 2 2 KH domain EF-hand_7 PF13499.6 CDJ84857.1 - 1.1e-10 41.8 0.9 1.6e-10 41.3 0.8 1.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ84857.1 - 2.6e-09 36.2 1.2 0.0022 17.8 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CDJ84857.1 - 3e-08 32.7 2.7 4.7e-05 22.6 0.8 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CDJ84857.1 - 7e-05 22.2 1.7 0.00022 20.6 0.3 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 CDJ84857.1 - 0.00051 19.8 0.8 0.0012 18.6 0.8 1.6 1 0 0 1 1 1 1 EF-hand domain pair Sigma54_CBD PF04963.13 CDJ84857.1 - 0.081 12.8 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain YorP PF09629.10 CDJ84857.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 YorP protein EF-hand_7 PF13499.6 CDJ84858.1 - 4.7e-11 43.0 0.3 9.1e-11 42.1 0.3 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CDJ84858.1 - 4e-10 38.5 2.0 2.7e-05 23.4 0.4 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CDJ84858.1 - 1.9e-09 36.7 0.7 0.00065 19.4 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDJ84858.1 - 5.7e-08 31.9 0.1 7.8e-05 22.0 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDJ84858.1 - 6.9e-06 25.8 2.5 0.0012 18.7 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair Sigma54_CBD PF04963.13 CDJ84858.1 - 0.017 15.0 0.0 0.022 14.6 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain SPARC_Ca_bdg PF10591.9 CDJ84858.1 - 0.097 13.0 1.4 3.5 8.0 0.5 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region FG-GAP PF01839.23 CDJ84858.1 - 0.31 11.2 3.5 0.73 10.0 1.0 2.4 2 0 0 2 2 2 0 FG-GAP repeat Dockerin_1 PF00404.18 CDJ84858.1 - 0.39 10.9 6.3 7.4 6.9 0.6 3.1 2 1 0 2 2 2 0 Dockerin type I domain Dynein_light PF01221.18 CDJ84859.1 - 6.3e-12 45.6 0.2 7.4e-12 45.4 0.2 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_6 PF13405.6 CDJ84860.1 - 1.7e-08 33.7 1.1 6.3e-05 22.6 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CDJ84860.1 - 2.2e-08 34.4 0.0 3.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CDJ84860.1 - 3e-06 26.4 3.2 0.024 14.2 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDJ84860.1 - 0.0045 16.8 1.0 1.1 9.1 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ84860.1 - 0.012 15.0 3.7 2.1 8.0 0.1 2.8 3 0 0 3 3 3 0 EF hand TFIIA PF03153.13 CDJ84860.1 - 2.9 7.8 26.8 4.3 7.2 26.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SNARE PF05739.19 CDJ84861.1 - 2.3e-07 30.7 0.0 2.3e-07 30.7 0.0 2.7 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 CDJ84861.1 - 3.4e-07 30.1 12.1 0.00019 21.1 0.5 2.3 2 0 0 2 2 2 2 Syntaxin Syntaxin-5_N PF11416.8 CDJ84861.1 - 1.5e-06 27.3 0.7 3.7e-06 26.0 0.7 1.8 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain DUF16 PF01519.16 CDJ84861.1 - 0.096 13.2 3.8 0.32 11.5 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 UPF0242 PF06785.11 CDJ84861.1 - 0.79 9.8 8.3 4.5 7.3 0.4 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Syntaxin_2 PF14523.6 CDJ84861.1 - 6.6 7.2 8.5 1.3e+02 3.1 0.1 3.3 2 1 1 3 3 3 0 Syntaxin-like protein GST_N_3 PF13417.6 CDJ84862.1 - 8e-06 26.2 0.0 2.4e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CDJ84862.1 - 0.00054 20.1 0.0 0.0029 17.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain AMP-binding PF00501.28 CDJ84863.1 - 5e-88 295.5 0.0 7.1e-88 295.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme HTH_48 PF17906.1 CDJ84863.1 - 1.9e-10 40.7 0.0 4.4e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 HTH domain in Mos1 transposase AMP-binding_C PF13193.6 CDJ84863.1 - 0.02 15.8 0.0 0.055 14.5 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Bud13 PF09736.9 CDJ84865.1 - 1.6 9.1 11.9 5.9 7.3 7.0 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex PRP3 PF08572.10 CDJ84867.1 - 1.7e-70 237.2 7.3 1.7e-70 237.2 7.3 3.5 2 1 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 CDJ84867.1 - 3.8e-43 147.1 1.5 3.8e-43 147.1 1.5 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF1115) CytochromB561_N PF09786.9 CDJ84868.1 - 7.8e-72 243.1 0.5 9.7e-72 242.8 0.5 1.1 1 0 0 1 1 1 1 Cytochrome B561, N terminal HLH PF00010.26 CDJ84869.1 - 2.5e-16 59.3 2.1 4.9e-16 58.4 2.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Neuro_bHLH PF12533.8 CDJ84869.1 - 7.5e-14 53.0 0.6 1.3e-13 52.2 0.6 1.4 1 0 0 1 1 1 1 Neuronal helix-loop-helix transcription factor Ion_trans PF00520.31 CDJ84870.1 - 2.1e-51 174.5 67.2 9.7e-27 93.8 25.6 4.1 3 1 1 4 4 4 4 Ion transport protein PKD_channel PF08016.12 CDJ84870.1 - 0.086 11.5 42.3 0.015 14.0 13.6 4.3 3 1 1 4 4 4 0 Polycystin cation channel Baculo_F PF12259.8 CDJ84870.1 - 0.095 11.2 0.0 0.22 10.0 0.0 1.6 1 0 0 1 1 1 0 Baculovirus F protein PsaF PF17550.2 CDJ84870.1 - 0.29 10.6 3.5 0.24 10.9 0.4 2.3 2 0 0 2 2 2 0 Family of unknown function RPN13_C PF16550.5 CDJ84870.1 - 0.53 10.5 2.6 1.3 9.3 0.5 2.4 1 1 1 2 2 2 0 UCH-binding domain DUF3742 PF12553.8 CDJ84870.1 - 1.7 8.8 6.4 1.6 8.9 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3742) DnaJ PF00226.31 CDJ84871.1 - 3.9e-17 62.1 0.1 7.3e-17 61.3 0.1 1.4 1 1 0 1 1 1 1 DnaJ domain RPT PF13446.6 CDJ84871.1 - 0.04 13.8 0.0 2 8.4 0.0 2.1 2 0 0 2 2 2 0 A repeated domain in UCH-protein Pepsin-I3 PF06394.13 CDJ84872.1 - 0.015 15.5 2.1 3.8 7.8 0.1 2.8 2 1 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain RT_RNaseH PF17917.1 CDJ84873.1 - 1.1e-14 54.6 0.1 3.9e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 CDJ84873.1 - 3.6e-08 33.9 0.0 7.7e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ84873.1 - 1.2e-06 29.0 0.0 2.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 CDJ84873.1 - 1.5e-05 25.0 0.0 6.1e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase PNMA PF14893.6 CDJ84873.1 - 0.00034 20.1 0.0 0.00059 19.3 0.0 1.3 1 0 0 1 1 1 1 PNMA RVP PF00077.20 CDJ84873.1 - 0.0015 18.8 0.0 0.0043 17.4 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ84873.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease rve PF00665.26 CDJ84874.1 - 5.4e-24 84.7 0.0 1.1e-23 83.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ84874.1 - 2.7e-07 30.6 0.1 5e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CDJ84874.1 - 1.2e-05 25.0 0.1 0.00065 19.4 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 CDJ84874.1 - 0.029 14.6 0.1 0.048 13.9 0.1 1.4 1 0 0 1 1 1 0 H2C2 zinc finger 7tm_1 PF00001.21 CDJ84875.1 - 2.5e-37 128.7 17.6 2.8e-37 128.5 17.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Strabismus PF06638.11 CDJ84875.1 - 0.11 11.1 0.7 0.16 10.6 0.7 1.1 1 0 0 1 1 1 0 Strabismus protein Hormone_recep PF00104.30 CDJ84876.1 - 7.6e-05 22.4 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 CDJ84877.1 - 8.9e-10 38.9 2.0 1.5e-09 38.1 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) C1_2 PF03107.16 CDJ84877.1 - 0.2 12.0 4.0 0.66 10.3 4.0 1.9 1 1 0 1 1 1 0 C1 domain NOA36 PF06524.12 CDJ84878.1 - 0.062 12.6 1.5 0.068 12.5 1.5 1.1 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 CDJ84878.1 - 0.15 12.4 8.2 0.25 11.7 8.2 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Imm5 PF14423.6 CDJ84878.1 - 0.29 11.3 1.7 0.37 11.0 1.7 1.1 1 0 0 1 1 1 0 Immunity protein Imm5 EamA PF00892.20 CDJ84879.1 - 3.1e-09 37.1 27.8 1.7e-08 34.7 9.1 2.5 3 0 0 3 3 3 2 EamA-like transporter family RVT_1 PF00078.27 CDJ84880.1 - 3.2e-07 30.1 0.0 3.4e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) polyprenyl_synt PF00348.17 CDJ84881.1 - 1e-70 237.7 0.2 1.3e-70 237.4 0.2 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Thioredoxin_6 PF13848.6 CDJ84882.1 - 9.7e-50 169.0 0.2 3.8e-42 144.3 0.0 3.0 1 1 2 3 3 3 3 Thioredoxin-like domain Thioredoxin PF00085.20 CDJ84882.1 - 9.7e-23 80.1 0.2 2.8e-22 78.7 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.13 CDJ84882.1 - 0.00021 20.7 1.1 0.00057 19.3 0.3 2.0 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CDJ84882.1 - 0.0033 17.6 0.1 0.051 13.8 0.2 2.3 2 0 0 2 2 2 1 Thioredoxin-like HyaE PF07449.11 CDJ84882.1 - 0.0055 16.7 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 CDJ84882.1 - 0.011 16.2 0.1 0.043 14.3 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin-like domain ERp29_N PF07912.13 CDJ84882.1 - 0.018 15.2 0.1 0.099 12.8 0.1 2.2 2 1 0 2 2 2 0 ERp29, N-terminal domain Thioredoxin_8 PF13905.6 CDJ84882.1 - 0.02 15.2 0.2 0.59 10.5 0.1 2.8 2 1 1 3 3 3 0 Thioredoxin-like Calsequestrin PF01216.17 CDJ84882.1 - 0.055 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Calsequestrin PAP2 PF01569.21 CDJ84883.1 - 2.9e-24 85.4 0.3 9.7e-24 83.7 0.2 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 CDJ84883.1 - 7.5e-11 42.1 0.3 1.1e-10 41.5 0.3 1.4 1 0 0 1 1 1 1 PAP2 superfamily Arfaptin PF06456.13 CDJ84884.1 - 2.2e-71 240.1 5.4 2.2e-71 240.1 5.4 1.5 1 1 1 2 2 2 1 Arfaptin-like domain BAR PF03114.18 CDJ84884.1 - 0.00041 20.1 4.2 0.00058 19.6 4.2 1.2 1 0 0 1 1 1 1 BAR domain FHA PF00498.26 CDJ84885.1 - 2.8e-18 66.0 0.0 5.4e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CDJ84885.1 - 9.3e-05 22.7 0.0 0.0018 18.5 0.0 2.4 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Sugar_tr PF00083.24 CDJ84886.1 - 3.5e-48 164.6 29.3 4.4e-48 164.3 29.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ84886.1 - 1.1e-17 64.1 26.9 1.1e-17 64.1 26.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Gal-bind_lectin PF00337.22 CDJ84887.1 - 1.3e-71 238.4 0.1 6.9e-36 122.7 0.0 2.1 2 0 0 2 2 2 2 Galactoside-binding lectin Alginate_lyase2 PF08787.11 CDJ84887.1 - 0.007 16.2 0.3 0.027 14.3 0.1 1.9 2 0 0 2 2 2 1 Alginate lyase BetaGal_dom4_5 PF13364.6 CDJ84887.1 - 0.12 13.0 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain ShK PF01549.24 CDJ84889.1 - 2.3e-13 50.4 34.5 7.9e-07 29.5 3.4 4.2 4 1 0 4 4 4 3 ShK domain-like ShK PF01549.24 CDJ84890.1 - 6.1e-19 68.3 53.3 1.7e-06 28.4 11.0 5.3 6 0 0 6 6 6 4 ShK domain-like ShK PF01549.24 CDJ84891.1 - 6.4e-19 68.2 50.2 6e-06 26.7 10.8 5.1 5 0 0 5 5 5 4 ShK domain-like ShK PF01549.24 CDJ84892.1 - 1.3e-20 73.7 53.0 2.3e-07 31.2 6.2 5.1 5 0 0 5 5 5 4 ShK domain-like TRP_2 PF08344.11 CDJ84893.1 - 6.3e-28 96.8 0.4 1.4e-27 95.6 0.4 1.7 1 0 0 1 1 1 1 Transient receptor ion channel II Ion_trans PF00520.31 CDJ84893.1 - 4.6e-26 91.5 13.0 4.6e-26 91.5 13.0 1.7 2 0 0 2 2 2 1 Ion transport protein Ank_2 PF12796.7 CDJ84893.1 - 6.2e-07 29.9 0.0 0.00081 19.9 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDJ84893.1 - 2e-05 24.6 0.3 0.089 13.4 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 CDJ84893.1 - 0.0083 16.7 0.0 0.86 10.3 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ84893.1 - 0.011 16.0 0.1 1.9 8.9 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) STAT_bind PF02864.15 CDJ84894.1 - 0.00018 22.1 0.0 0.00043 20.8 0.0 1.6 1 0 0 1 1 1 1 STAT protein, DNA binding domain SH2 PF00017.24 CDJ84894.1 - 0.014 15.5 0.0 0.047 13.8 0.0 1.9 1 0 0 1 1 1 0 SH2 domain STAT_alpha PF01017.20 CDJ84894.1 - 0.24 11.3 1.6 0.25 11.2 0.4 1.6 2 0 0 2 2 2 0 STAT protein, all-alpha domain p450 PF00067.22 CDJ84895.1 - 5.8e-30 104.5 0.0 6.2e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF851 PF05867.11 CDJ84896.1 - 1.2e-10 41.3 1.0 2.5e-10 40.3 0.9 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF851) Ribophorin_II PF05817.14 CDJ84897.1 - 1.8e-93 314.2 0.0 2e-93 314.1 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II ACOX PF01756.19 CDJ84898.1 - 9.7e-54 181.7 0.2 2.1e-53 180.5 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 CDJ84898.1 - 3.3e-29 102.0 0.1 1e-28 100.4 0.0 1.9 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 CDJ84898.1 - 1.6e-10 41.1 0.0 3.1e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 CDJ84898.1 - 0.0022 18.2 1.1 0.012 15.9 0.1 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Lectin_C PF00059.21 CDJ84899.1 - 1.7e-34 118.8 8.1 2.1e-17 63.8 3.8 2.1 2 0 0 2 2 2 2 Lectin C-type domain Intimin_C PF07979.11 CDJ84899.1 - 0.93 10.0 5.8 1.3 9.5 0.7 2.8 3 0 0 3 3 3 0 Intimin C-type lectin domain Lectin_C PF00059.21 CDJ84900.1 - 5.4e-49 165.4 12.7 7.7e-18 65.2 0.3 3.2 3 0 0 3 3 3 3 Lectin C-type domain CBM_14 PF01607.24 CDJ84900.1 - 1.1 9.5 0.0 1.1 9.5 0.0 5.4 5 1 0 5 5 5 0 Chitin binding Peritrophin-A domain PEARLI-4 PF05278.12 CDJ84901.1 - 0.048 13.2 3.0 0.089 12.4 3.0 1.4 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Fib_alpha PF08702.10 CDJ84901.1 - 0.12 12.5 2.5 0.14 12.3 1.1 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Cas_Csy4 PF09618.10 CDJ84903.1 - 0.052 13.7 0.1 0.067 13.3 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Y_phosphatase PF00102.27 CDJ84905.1 - 7.3e-54 182.8 0.0 1.3e-53 182.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Sugar_tr PF00083.24 CDJ84906.1 - 9.5e-106 354.3 33.7 3.4e-82 276.7 17.1 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CDJ84906.1 - 6e-28 97.8 26.3 1.2e-25 90.2 18.1 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CDJ84906.1 - 0.00048 18.7 4.7 0.00048 18.7 4.7 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) HemeBinding_Shp PF11545.8 CDJ84906.1 - 0.091 12.7 0.3 0.22 11.5 0.3 1.6 1 0 0 1 1 1 0 Cell surface heme-binding protein Shp COX7B PF05392.11 CDJ84906.1 - 3.9 7.2 6.5 12 5.7 0.4 2.6 2 0 0 2 2 2 0 Cytochrome C oxidase chain VIIB NUDIX PF00293.28 CDJ84908.1 - 1.7e-13 50.7 0.0 2.6e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 CDJ84908.1 - 3.7e-05 23.3 4.3 6.1e-05 22.6 4.3 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain IBR PF01485.21 CDJ84908.1 - 0.029 14.6 0.3 0.054 13.7 0.3 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DZR PF12773.7 CDJ84908.1 - 0.035 14.1 0.6 0.078 13.0 0.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon Nudix_N_2 PF14803.6 CDJ84908.1 - 0.12 12.3 1.9 0.4 10.6 1.9 1.9 1 1 0 1 1 1 0 Nudix N-terminal zf_C2H2_13 PF18508.1 CDJ84908.1 - 0.13 11.9 0.2 0.26 10.9 0.2 1.5 1 0 0 1 1 1 0 Zinc finger domain VP_N-CPKC PF11475.8 CDJ84908.1 - 0.14 12.1 1.1 2.3 8.2 0.0 2.5 2 0 0 2 2 2 0 Virion protein N terminal domain zinc_ribbon_2 PF13240.6 CDJ84908.1 - 0.17 11.7 2.0 0.28 11.0 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Auto_anti-p27 PF06677.12 CDJ84908.1 - 0.19 11.9 0.9 0.41 10.8 0.9 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-ribbon_3 PF13248.6 CDJ84908.1 - 0.3 10.5 5.8 2.4 7.7 5.8 2.2 1 1 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 CDJ84908.1 - 0.43 10.7 3.5 1.9 8.7 0.1 2.4 1 1 1 2 2 2 0 Zinc ribbon domain zf-C4_Topoisom PF01396.19 CDJ84908.1 - 0.68 9.8 5.2 3 7.7 5.2 2.0 1 1 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger DUF35_N PF12172.8 CDJ84908.1 - 0.99 9.4 6.3 7.9 6.5 0.4 2.5 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) TBCC PF07986.12 CDJ84909.1 - 0.055 13.2 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 Tubulin binding cofactor C Aa_trans PF01490.18 CDJ84910.1 - 2.1e-30 105.8 26.0 1e-15 57.4 11.5 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein TMEMspv1-c74-12 PF11044.8 CDJ84910.1 - 0.53 10.3 1.5 2.3 8.3 1.5 2.1 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein PC4 PF02229.16 CDJ84911.1 - 4.7e-24 83.8 0.1 1.1e-23 82.6 0.1 1.6 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) SOG2 PF10428.9 CDJ84911.1 - 0.36 10.0 4.6 0.36 10.0 4.6 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 CDJ84911.1 - 0.61 8.8 3.8 0.54 9.0 3.8 1.1 1 0 0 1 1 1 0 Presenilin Rtf2 PF04641.12 CDJ84911.1 - 0.97 8.7 12.0 1.2 8.4 12.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger RNA_pol_Rpc4 PF05132.14 CDJ84911.1 - 1.3 9.4 9.9 1.8 9.0 9.9 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Sec62 PF03839.16 CDJ84911.1 - 1.4 8.3 7.1 1.8 8.0 7.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 CDC45 PF02724.14 CDJ84911.1 - 1.5 7.0 6.3 1.2 7.3 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 CDJ84911.1 - 1.8 7.3 8.0 1.6 7.4 8.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AP3D1 PF06375.11 CDJ84911.1 - 1.8 8.8 18.6 2.6 8.2 18.6 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Connexin PF00029.19 CDJ84911.1 - 5.2 6.8 5.7 5.6 6.7 5.7 1.2 1 0 0 1 1 1 0 Connexin DUF4637 PF15470.6 CDJ84911.1 - 5.5 6.7 12.5 3.9 7.2 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4637) Glyoxal_oxid_N PF07250.11 CDJ84912.1 - 0.039 13.2 2.4 0.089 12.0 2.4 1.5 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus Spo7_2_N PF15407.6 CDJ84912.1 - 0.068 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 Lectin_C PF00059.21 CDJ84913.1 - 1.2e-17 64.6 2.4 2.7e-17 63.5 2.4 1.6 1 0 0 1 1 1 1 Lectin C-type domain EGF_2 PF07974.13 CDJ84913.1 - 0.0023 18.3 40.6 0.077 13.4 1.7 5.9 5 0 0 5 5 5 4 EGF-like domain EGF PF00008.27 CDJ84913.1 - 8.6 6.8 46.6 0.44 10.9 2.7 6.0 5 0 0 5 5 5 0 EGF-like domain Collagen PF01391.18 CDJ84914.1 - 6.4e-21 73.9 112.2 4.6e-10 39.1 32.5 5.1 3 1 2 5 5 5 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ84914.1 - 1.5e-10 40.9 0.1 2e-10 40.6 0.1 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain OsmC PF02566.19 CDJ84914.1 - 0.11 13.0 0.0 0.16 12.5 0.0 1.2 1 0 0 1 1 1 0 OsmC-like protein Kazal_2 PF07648.15 CDJ84915.1 - 2.3e-70 232.5 140.9 4.4e-11 42.7 4.8 14.3 13 1 1 14 14 14 13 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CDJ84915.1 - 1.8e-52 175.1 130.0 6.6e-09 35.6 1.0 13.9 13 2 2 15 15 15 12 Kazal-type serine protease inhibitor domain Protamine_P2 PF00841.19 CDJ84915.1 - 5 7.7 11.2 0.98 9.9 0.5 3.7 4 0 0 4 4 4 0 Sperm histone P2 DUF2353 PF09789.9 CDJ84916.1 - 2.4e-63 214.4 24.4 2.8e-63 214.2 24.4 1.0 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) ZapB PF06005.12 CDJ84916.1 - 0.00029 21.2 28.0 0.039 14.4 4.6 4.8 4 1 0 4 4 4 2 Cell division protein ZapB GAS PF13851.6 CDJ84916.1 - 0.0007 19.0 0.4 0.0007 19.0 0.4 4.1 3 2 0 3 3 3 1 Growth-arrest specific micro-tubule binding YabA PF06156.13 CDJ84916.1 - 0.0017 19.0 24.2 0.16 12.6 1.4 4.2 2 1 2 4 4 3 2 Initiation control protein YabA ERM PF00769.19 CDJ84916.1 - 0.0026 17.6 14.7 0.0026 17.6 14.7 2.1 1 1 1 2 2 2 1 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.9 CDJ84916.1 - 0.011 15.8 4.9 0.011 15.8 4.9 4.5 3 2 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 CDJ84916.1 - 0.025 14.4 1.1 0.025 14.4 1.1 4.9 5 1 1 6 6 5 0 Septum formation initiator Lebercilin PF15619.6 CDJ84916.1 - 0.034 13.8 32.1 0.059 13.0 12.7 4.1 3 2 1 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease PI_PP_I PF18363.1 CDJ84916.1 - 0.059 13.6 2.1 0.21 11.8 0.3 2.6 2 1 1 3 3 2 0 Phosphoinositide phosphatase insertion domain ATG16 PF08614.11 CDJ84916.1 - 0.081 13.1 30.1 0.45 10.7 5.1 4.3 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) DUF2630 PF10944.8 CDJ84916.1 - 0.081 13.4 5.8 2.5 8.6 0.7 3.4 3 0 0 3 3 2 0 Protein of unknown function (DUF2630) Prefoldin_3 PF13758.6 CDJ84916.1 - 0.092 12.8 11.2 0.7 10.0 0.2 4.3 2 2 1 4 4 4 0 Prefoldin subunit DUF3450 PF11932.8 CDJ84916.1 - 0.11 11.8 18.2 0.68 9.2 0.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Csm1_N PF18504.1 CDJ84916.1 - 0.14 12.5 0.0 0.14 12.5 0.0 4.8 4 1 2 6 6 5 0 Csm1 N-terminal domain SlyX PF04102.12 CDJ84916.1 - 0.46 11.1 15.5 3.2 8.4 2.8 5.1 4 2 1 5 5 5 0 SlyX TolA_bind_tri PF16331.5 CDJ84916.1 - 0.92 9.6 10.0 1.6 8.8 2.9 3.8 3 0 0 3 3 3 0 TolA binding protein trimerisation Spc7 PF08317.11 CDJ84916.1 - 1 8.2 28.3 1.6 7.5 2.4 3.1 2 2 0 3 3 3 0 Spc7 kinetochore protein Mto2_bdg PF12808.7 CDJ84916.1 - 1 9.7 11.8 2.3 8.6 0.1 4.2 3 1 1 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region APG6_N PF17675.1 CDJ84916.1 - 1.5 9.4 33.3 2.9 8.4 3.5 4.4 2 2 3 5 5 5 0 Apg6 coiled-coil region TSC22 PF01166.18 CDJ84916.1 - 2 8.8 14.6 7.1 7.0 0.5 5.5 5 2 1 6 6 4 0 TSC-22/dip/bun family JAKMIP_CC3 PF16034.5 CDJ84916.1 - 2.1 8.2 19.8 4.3 7.2 14.2 2.6 1 1 1 2 2 2 0 JAKMIP CC3 domain MtrG PF04210.13 CDJ84916.1 - 4.2 7.3 5.7 1 9.2 0.1 2.9 4 0 0 4 4 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G ADIP PF11559.8 CDJ84916.1 - 4.5 7.3 24.1 0.47 10.5 3.2 4.0 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding SOGA PF11365.8 CDJ84916.1 - 4.6 8.4 20.6 2.3 9.4 0.4 4.1 2 1 2 4 4 4 0 Protein SOGA DUF1664 PF07889.12 CDJ84916.1 - 4.8 7.2 21.2 1.4 9.0 3.0 4.3 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) LPP PF04728.13 CDJ84916.1 - 5.2 7.5 10.7 7.9 7.0 0.2 4.4 5 1 0 5 5 4 0 Lipoprotein leucine-zipper Seryl_tRNA_N PF02403.22 CDJ84916.1 - 5.3 7.3 24.9 4.3 7.6 2.8 4.4 3 3 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain GIT_CC PF16559.5 CDJ84916.1 - 5.4 7.0 15.6 7.6 6.5 0.5 5.0 4 3 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Syntaxin_2 PF14523.6 CDJ84916.1 - 5.5 7.4 16.0 7.8 6.9 9.0 3.8 1 1 3 4 4 4 0 Syntaxin-like protein Fez1 PF06818.15 CDJ84916.1 - 6.4 7.2 27.0 7.4 7.0 2.0 3.1 1 1 1 2 2 2 0 Fez1 Filament PF00038.21 CDJ84916.1 - 6.6 6.2 30.1 24 4.4 22.9 3.2 1 1 1 2 2 2 0 Intermediate filament protein TPR_MLP1_2 PF07926.12 CDJ84916.1 - 9.6 6.3 24.6 3 7.9 11.8 3.4 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein GHMP_kinases_N PF00288.26 CDJ84917.1 - 6.3e-13 48.8 1.5 6.5e-13 48.7 0.2 1.7 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CDJ84917.1 - 8.3e-08 32.5 0.0 2.3e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 CDJ84917.1 - 0.012 15.2 0.1 0.023 14.2 0.1 1.4 1 0 0 1 1 1 0 Galactokinase galactose-binding signature RT_RNaseH_2 PF17919.1 CDJ84918.1 - 7.5e-24 83.7 0.1 3.1e-23 81.7 0.1 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ84918.1 - 1.1e-17 64.3 0.0 1.8e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDJ84918.1 - 8.7e-14 51.7 0.0 8.4e-13 48.5 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DLIC PF05783.11 CDJ84920.1 - 1.8e-11 43.5 0.2 9.6e-11 41.2 0.0 1.9 1 1 1 2 2 2 1 Dynein light intermediate chain (DLIC) Roc PF08477.13 CDJ84920.1 - 7.1e-06 26.2 0.0 3.7e-05 23.9 0.0 2.1 1 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 CDJ84920.1 - 2.2e-05 24.7 0.1 5.4e-05 23.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ84920.1 - 0.00012 22.5 0.1 0.00054 20.4 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 CDJ84920.1 - 0.00016 21.2 0.0 0.00037 19.9 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family TniB PF05621.11 CDJ84920.1 - 0.0003 20.2 0.1 0.0014 18.1 0.0 2.0 2 1 1 3 3 3 1 Bacterial TniB protein G-alpha PF00503.20 CDJ84920.1 - 0.0029 16.8 0.2 0.0051 16.0 0.2 1.4 1 0 0 1 1 1 1 G-protein alpha subunit Ras PF00071.22 CDJ84920.1 - 0.0035 16.9 0.0 0.042 13.5 0.0 2.2 2 0 0 2 2 2 1 Ras family SRPRB PF09439.10 CDJ84920.1 - 0.0066 15.9 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATPase_2 PF01637.18 CDJ84920.1 - 0.0086 16.0 0.2 0.017 15.0 0.0 1.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 CDJ84920.1 - 0.013 15.4 0.1 0.031 14.2 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 CDJ84920.1 - 0.014 15.1 0.1 0.029 14.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 CDJ84920.1 - 0.02 15.3 0.0 0.097 13.1 0.0 2.1 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.23 CDJ84920.1 - 0.021 14.9 0.1 0.047 13.8 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 CDJ84920.1 - 0.028 14.3 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 NTPase Septin PF00735.18 CDJ84920.1 - 0.036 13.3 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 Septin ABC_tran PF00005.27 CDJ84920.1 - 0.046 14.2 0.0 0.094 13.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 CDJ84920.1 - 0.066 13.2 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDJ84920.1 - 0.15 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Dickkopf_N PF04706.12 CDJ84921.1 - 0.0094 16.4 1.0 0.0094 16.4 1.0 4.4 4 0 0 4 4 4 3 Dickkopf N-terminal cysteine-rich region Dickkopf_N PF04706.12 CDJ84922.1 - 8.8 6.9 10.1 0.18 12.3 1.2 2.5 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region EFF-AFF PF14884.6 CDJ84923.1 - 2.8e-72 243.7 2.6 5e-72 242.9 2.6 1.3 1 1 0 1 1 1 1 Type I membrane glycoproteins cell-cell fusogen DUF1289 PF06945.13 CDJ84923.1 - 3.9 7.4 7.8 0.29 11.0 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) DNTTIP1_dimer PF18192.1 CDJ84924.1 - 3.2e-24 85.0 0.2 6e-24 84.2 0.2 1.5 1 0 0 1 1 1 1 DNTTIP1 dimerisation domain AT_hook PF02178.19 CDJ84924.1 - 0.013 15.3 2.2 0.036 13.9 2.2 1.8 1 0 0 1 1 1 0 AT hook motif SNF PF00209.18 CDJ84925.1 - 7.2e-126 420.9 20.9 9.1e-126 420.6 20.9 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family U1snRNP70_N PF12220.8 CDJ84926.1 - 0.055 14.1 0.7 0.071 13.8 0.7 1.1 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal gag-asp_proteas PF13975.6 CDJ84927.1 - 1.1e-07 32.4 0.1 4.2e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ84927.1 - 1.5e-07 31.9 0.0 4.7e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 CDJ84927.1 - 0.01 16.1 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease AAA_32 PF13654.6 CDJ84927.1 - 0.09 11.5 1.7 0.78 8.4 0.4 2.1 2 0 0 2 2 2 0 AAA domain Ima1_N PF09779.9 CDJ84927.1 - 0.65 10.9 10.1 0.18 12.6 4.8 2.5 2 1 1 3 3 3 0 Ima1 N-terminal domain zf-CCHC_4 PF14392.6 CDJ84927.1 - 8.7 6.2 7.6 0.45 10.3 0.4 2.7 3 0 0 3 3 3 0 Zinc knuckle RT_RNaseH_2 PF17919.1 CDJ84928.1 - 2.2e-35 120.7 0.1 5.4e-35 119.4 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ84928.1 - 1.3e-32 112.2 0.0 3.3e-32 110.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ84928.1 - 5.9e-23 81.3 0.1 3e-22 79.1 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ84928.1 - 8.7e-19 67.4 0.1 2.1e-18 66.2 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 CDJ84928.1 - 1e-09 38.3 0.0 1.8e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 CDJ84928.1 - 8.9e-06 25.4 0.0 2.8e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CDJ84928.1 - 9.5e-05 22.5 0.1 0.00023 21.3 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger HTH_29 PF13551.6 CDJ84930.1 - 3.6e-11 42.9 0.6 2.1e-09 37.3 0.1 2.4 1 1 1 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 CDJ84930.1 - 1.4e-09 37.5 0.4 6.3e-07 29.0 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 CDJ84930.1 - 7.8e-09 35.5 0.0 1e-05 25.6 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain MarR_2 PF12802.7 CDJ84930.1 - 2.5e-07 30.5 0.5 0.00099 19.0 0.1 2.4 2 0 0 2 2 2 2 MarR family HTH_24 PF13412.6 CDJ84930.1 - 9.3e-06 25.1 0.3 0.059 12.9 0.0 2.4 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_32 PF13565.6 CDJ84930.1 - 1.7e-05 25.3 4.1 1.8e-05 25.2 2.5 1.9 2 1 1 3 3 2 1 Homeodomain-like domain TrmB PF01978.19 CDJ84930.1 - 4.2e-05 23.3 0.8 0.003 17.4 0.2 2.3 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_Tnp_ISL3 PF13542.6 CDJ84930.1 - 4.3e-05 22.8 1.7 0.34 10.4 0.1 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 DUF4423 PF14394.6 CDJ84930.1 - 7.8e-05 22.4 1.0 0.00012 21.9 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_Crp_2 PF13545.6 CDJ84930.1 - 8.8e-05 22.4 0.7 0.00032 20.6 0.2 2.0 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain HTH_11 PF08279.12 CDJ84930.1 - 0.00011 22.1 0.4 0.048 13.6 0.0 2.5 2 0 0 2 2 2 1 HTH domain HTH_Tnp_Tc3_2 PF01498.18 CDJ84930.1 - 0.00015 22.0 1.6 0.00032 20.9 1.6 1.5 1 0 0 1 1 1 1 Transposase HTH_AsnC-type PF13404.6 CDJ84930.1 - 0.00016 21.4 0.1 0.42 10.5 0.0 2.4 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain MarR PF01047.22 CDJ84930.1 - 0.00022 21.1 0.5 0.26 11.2 0.0 2.7 3 0 0 3 3 2 2 MarR family HTH_38 PF13936.6 CDJ84930.1 - 0.00031 20.4 0.6 0.2 11.4 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 CDJ84930.1 - 0.0015 18.0 1.9 0.39 10.3 0.3 2.8 2 1 1 3 3 3 1 Sigma-70, region 4 HTH_7 PF02796.15 CDJ84930.1 - 0.0022 18.0 0.0 2.2 8.4 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_Tnp_IS630 PF01710.16 CDJ84930.1 - 0.0026 17.8 5.6 0.0041 17.2 5.6 1.4 1 1 0 1 1 1 1 Transposase HTH_18 PF12833.7 CDJ84930.1 - 0.0032 17.7 0.3 0.025 14.8 0.0 2.3 3 0 0 3 3 2 1 Helix-turn-helix domain HTH_psq PF05225.16 CDJ84930.1 - 0.0033 17.1 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_IclR PF09339.10 CDJ84930.1 - 0.0056 16.4 0.0 0.34 10.7 0.0 2.3 2 0 0 2 2 2 1 IclR helix-turn-helix domain PAX PF00292.18 CDJ84930.1 - 0.0087 16.0 0.3 0.016 15.1 0.3 1.4 1 1 0 1 1 1 1 'Paired box' domain HTH_17 PF12728.7 CDJ84930.1 - 0.0092 16.1 0.1 3.2 8.0 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain CENP-B_N PF04218.13 CDJ84930.1 - 0.014 15.0 0.4 6.3 6.5 0.0 2.6 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain DUF1018 PF06252.12 CDJ84930.1 - 0.021 15.8 2.2 0.03 15.3 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) HTH_27 PF13463.6 CDJ84930.1 - 0.031 14.8 1.2 0.21 12.1 0.2 2.2 1 1 1 2 2 2 0 Winged helix DNA-binding domain HTH_Tnp_Tc3_1 PF11427.8 CDJ84930.1 - 0.032 14.1 1.1 0.061 13.2 0.3 1.8 2 0 0 2 2 2 0 Tc3 transposase MerR_1 PF13411.6 CDJ84930.1 - 0.039 14.0 1.1 0.94 9.6 0.1 2.4 2 1 0 2 2 2 0 MerR HTH family regulatory protein Rrf2 PF02082.20 CDJ84930.1 - 0.051 13.9 0.4 5.5 7.4 0.1 2.3 2 0 0 2 2 2 0 Transcriptional regulator HTH_6 PF01418.17 CDJ84930.1 - 0.071 13.1 0.0 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family HTH_36 PF13730.6 CDJ84930.1 - 0.077 13.0 0.1 3.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_26 PF13443.6 CDJ84930.1 - 0.091 13.2 1.0 6.4 7.3 0.0 2.5 3 0 0 3 3 2 0 Cro/C1-type HTH DNA-binding domain HTH_35 PF13693.6 CDJ84930.1 - 0.11 12.6 0.2 17 5.5 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_1 PF01527.20 CDJ84930.1 - 0.11 12.8 3.6 0.89 9.9 0.1 2.5 2 1 1 3 3 2 0 Transposase eIF3_N PF09440.10 CDJ84930.1 - 0.36 11.3 1.7 0.78 10.2 0.5 2.1 2 1 0 2 2 2 0 eIF3 subunit 6 N terminal domain ABC_tran PF00005.27 CDJ84931.1 - 1.8e-49 167.8 1.6 1.5e-25 90.3 0.0 3.1 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 CDJ84931.1 - 1.6e-14 54.4 9.1 0.0018 18.2 0.0 4.4 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDJ84931.1 - 7.8e-11 41.8 1.4 0.0084 15.6 0.0 4.3 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CDJ84931.1 - 1.7e-08 34.6 2.2 0.0017 18.1 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.6 CDJ84931.1 - 4e-06 26.9 0.8 0.018 15.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 CDJ84931.1 - 5.3e-06 26.9 0.1 0.13 12.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 CDJ84931.1 - 5.4e-06 26.1 1.0 0.01 15.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 CDJ84931.1 - 2.2e-05 24.7 0.2 0.094 13.0 0.0 2.7 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 CDJ84931.1 - 2.7e-05 24.2 1.3 0.0028 17.7 0.3 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 CDJ84931.1 - 3.4e-05 23.7 1.0 0.25 11.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 CDJ84931.1 - 4.9e-05 23.3 4.6 0.021 14.8 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase NB-ARC PF00931.22 CDJ84931.1 - 5.3e-05 22.5 0.1 0.25 10.5 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_22 PF13401.6 CDJ84931.1 - 9.9e-05 22.6 2.9 0.42 10.9 0.0 3.1 3 1 0 3 3 2 2 AAA domain NACHT PF05729.12 CDJ84931.1 - 0.00014 21.8 3.1 0.16 11.9 0.1 2.8 2 1 1 3 3 3 2 NACHT domain AAA_33 PF13671.6 CDJ84931.1 - 0.00017 21.8 0.1 0.41 10.8 0.1 3.0 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 CDJ84931.1 - 0.00019 21.9 0.1 0.069 13.6 0.0 3.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CDJ84931.1 - 0.00021 21.9 4.6 0.19 12.3 0.1 3.8 4 1 0 4 4 3 2 AAA domain RNA_helicase PF00910.22 CDJ84931.1 - 0.00072 19.9 0.5 1.1 9.6 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_25 PF13481.6 CDJ84931.1 - 0.0012 18.5 0.2 2.4 7.7 0.0 3.3 3 1 0 3 3 3 1 AAA domain Roc PF08477.13 CDJ84931.1 - 0.0014 18.9 1.1 2.3 8.4 0.0 3.4 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 CDJ84931.1 - 0.0046 16.7 6.6 0.11 12.2 0.1 3.6 3 2 0 4 4 4 1 AAA domain NTPase_1 PF03266.15 CDJ84931.1 - 0.006 16.5 2.8 3.1 7.7 0.1 3.2 2 1 0 2 2 2 1 NTPase cobW PF02492.19 CDJ84931.1 - 0.0064 16.1 1.1 0.29 10.7 0.0 2.7 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran_Xtn PF12848.7 CDJ84931.1 - 0.0076 16.3 17.6 0.099 12.7 17.1 3.0 2 1 0 2 2 1 1 ABC transporter AAA_23 PF13476.6 CDJ84931.1 - 0.0097 16.4 21.4 0.13 12.7 0.0 4.2 4 1 0 4 4 4 2 AAA domain AAA_5 PF07728.14 CDJ84931.1 - 0.02 14.9 0.5 5.6 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 CDJ84931.1 - 0.032 14.1 3.0 0.57 10.1 0.0 3.1 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea SRP54 PF00448.22 CDJ84931.1 - 0.05 13.2 1.9 5 6.7 0.1 2.9 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain OMP_b-brl PF13505.6 CDJ84931.1 - 0.054 13.6 0.5 2.7 8.1 0.4 2.5 2 0 0 2 2 2 0 Outer membrane protein beta-barrel domain PduV-EutP PF10662.9 CDJ84931.1 - 0.057 13.2 0.1 15 5.3 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 CDJ84931.1 - 0.057 13.7 1.2 5.8 7.2 0.0 3.2 3 1 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 CDJ84931.1 - 0.069 12.8 0.0 2.8 7.5 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.6 CDJ84931.1 - 0.12 12.7 0.6 4.7 7.5 0.2 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit FeoB_N PF02421.18 CDJ84931.1 - 0.14 11.7 0.2 2.1 7.9 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B MobB PF03205.14 CDJ84931.1 - 0.14 12.0 0.9 24 4.8 0.0 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_7 PF12775.7 CDJ84931.1 - 0.32 10.5 4.6 8.8 5.8 0.0 3.1 4 0 0 4 4 3 0 P-loop containing dynein motor region Colicin-DNase PF12639.7 CDJ84931.1 - 0.33 11.8 4.5 1.3 9.9 4.5 2.1 1 0 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin DUF3987 PF13148.6 CDJ84931.1 - 0.59 9.1 3.3 8.2 5.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) DUF87 PF01935.17 CDJ84931.1 - 0.74 9.9 0.0 0.74 9.9 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain DUF1151 PF06625.11 CDJ84931.1 - 1.4 8.9 10.3 1.6 8.7 5.8 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF1151) SURF2 PF05477.11 CDJ84931.1 - 1.9 8.2 10.8 0.14 11.8 5.5 1.7 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Dynamin_N PF00350.23 CDJ84931.1 - 2.3 8.3 5.8 4.2 7.4 0.0 3.3 2 1 0 3 3 3 0 Dynamin family Kunitz_BPTI PF00014.23 CDJ84932.1 - 1.7e-22 79.4 18.0 1.7e-13 50.6 5.7 2.7 3 0 0 3 3 3 2 Kunitz/Bovine pancreatic trypsin inhibitor domain SPAN-X PF07458.12 CDJ84932.1 - 0.087 13.3 0.2 0.15 12.5 0.2 1.3 1 0 0 1 1 1 0 Sperm protein associated with nucleus, mapped to X chromosome 7tm_1 PF00001.21 CDJ84933.1 - 3.8e-20 72.3 0.0 3.8e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ84933.1 - 3.5e-05 23.3 3.3 4.7e-05 22.9 3.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TAS2R PF05296.13 CDJ84933.1 - 0.0023 17.1 0.6 0.0031 16.7 0.6 1.1 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) 7TM_GPCR_Srw PF10324.9 CDJ84933.1 - 0.0051 16.1 2.6 0.0051 16.1 2.6 1.4 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 CDJ84933.1 - 0.0078 15.6 2.2 0.011 15.1 2.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv DUF2207 PF09972.9 CDJ84933.1 - 0.013 14.3 0.1 0.017 13.9 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4448 PF14610.6 CDJ84933.1 - 0.068 12.9 0.2 0.1 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Spore_III_AB PF09548.10 CDJ84933.1 - 0.14 12.2 0.4 1.8 8.6 0.1 2.6 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Piezo_RRas_bdg PF12166.8 CDJ84933.1 - 0.33 10.2 2.7 0.22 10.8 0.9 1.5 2 0 0 2 2 2 0 Piezo non-specific cation channel, R-Ras-binding domain Voltage_CLC PF00654.20 CDJ84934.1 - 2e-26 93.1 4.2 2e-26 93.1 4.2 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel HILPDA PF15220.6 CDJ84934.1 - 0.054 13.6 0.6 0.16 12.1 0.6 1.7 1 0 0 1 1 1 0 Hypoxia-inducible lipid droplet-associated 7tm_1 PF00001.21 CDJ84935.1 - 1.4e-17 63.9 15.7 1.9e-17 63.4 15.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Astacin PF01400.24 CDJ84936.1 - 0.012 15.2 0.0 0.41 10.2 0.0 2.5 2 1 0 2 2 2 0 Astacin (Peptidase family M12A) GPCR_chapero_1 PF11904.8 CDJ84937.1 - 2e-90 303.4 5.4 1.1e-59 202.3 0.0 2.1 2 0 0 2 2 2 2 GPCR-chaperone Ank_2 PF12796.7 CDJ84937.1 - 6.6e-16 58.7 0.1 4.2e-11 43.3 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDJ84937.1 - 1.6e-10 40.2 0.0 0.39 11.4 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 CDJ84937.1 - 4.4e-09 36.4 0.0 0.28 11.7 0.7 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 CDJ84937.1 - 9.4e-06 26.1 0.0 0.068 13.8 0.1 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ84937.1 - 0.00056 20.1 0.1 0.1 12.9 0.1 3.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) CHDCT2 PF08074.11 CDJ84937.1 - 0.0022 18.2 0.0 3.6 7.8 0.0 2.5 2 0 0 2 2 2 2 CHDCT2 (NUC038) domain POX PF07526.11 CDJ84937.1 - 0.013 16.1 0.1 6.7 7.3 0.0 2.5 2 0 0 2 2 2 0 Associated with HOX Methyltransf_18 PF12847.7 CDJ84937.1 - 0.034 14.1 0.8 13 5.7 0.1 2.9 3 0 0 3 3 3 0 Methyltransferase domain DUF4951 PF16309.5 CDJ84937.1 - 0.044 13.8 0.0 29 4.8 0.0 3.2 3 0 0 3 3 3 0 Domian of unknown function (DUF4951) HTH_13 PF11972.8 CDJ84937.1 - 0.045 13.8 0.2 21 5.3 0.0 2.8 3 0 0 3 3 3 0 HTH DNA binding domain TRAP-delta PF05404.12 CDJ84937.1 - 0.061 12.8 0.4 13 5.3 0.1 2.3 2 0 0 2 2 2 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) FdsD PF11390.8 CDJ84937.1 - 0.065 13.6 0.0 27 5.2 0.0 2.8 2 0 0 2 2 2 0 NADH-dependant formate dehydrogenase delta subunit FdsD DUF2155 PF09923.9 CDJ84937.1 - 0.11 12.7 0.3 27 5.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2155) CHASE8 PF17152.4 CDJ84937.1 - 0.12 12.7 0.0 1.8e+02 2.5 0.0 4.2 4 0 0 4 4 4 0 Periplasmic sensor domain 4_1_CTD PF05902.13 CDJ84937.1 - 0.13 12.4 0.8 21 5.2 0.1 2.3 2 0 0 2 2 2 0 4.1 protein C-terminal domain (CTD) eIF-5a PF01287.20 CDJ84939.1 - 2.1e-24 85.4 0.1 3e-24 84.9 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CDJ84939.1 - 0.0015 18.5 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain EPL1 PF10513.9 CDJ84940.1 - 8e-08 32.8 0.4 1.7e-07 31.7 0.0 1.8 3 0 0 3 3 3 1 Enhancer of polycomb-like Ferlin_C PF16165.5 CDJ84941.1 - 2.5e-27 95.7 0.2 1.1e-26 93.6 0.2 2.2 1 1 0 1 1 1 1 Ferlin C-terminus C2 PF00168.30 CDJ84941.1 - 7.3e-26 90.4 4.2 5.3e-12 45.9 0.0 6.1 4 2 1 5 5 5 3 C2 domain FerB PF08150.12 CDJ84941.1 - 2e-18 66.8 0.0 4.5e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 FerB (NUC096) domain PTEN_C2 PF10409.9 CDJ84941.1 - 0.0063 16.3 1.2 0.015 15.1 0.2 2.1 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein DUF4486 PF14858.6 CDJ84941.1 - 0.025 13.1 0.1 0.041 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4486) CPG4 PF15481.6 CDJ84942.1 - 0.011 16.4 6.3 0.04 14.5 1.7 2.6 1 1 1 2 2 2 0 Chondroitin proteoglycan 4 FSA_C PF10479.9 CDJ84942.1 - 3.1 5.8 12.1 4.3 5.3 12.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF1406 PF07190.11 CDJ84942.1 - 9.8 6.1 10.8 0.07 13.1 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1406) DUF4070 PF13282.6 CDJ84943.1 - 0.027 14.6 0.5 0.033 14.3 0.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4070) zf-H2C2_2 PF13465.6 CDJ84945.1 - 8.5e-25 86.0 30.4 4.8e-08 33.1 2.2 4.7 4 0 0 4 4 4 4 Zinc-finger double domain Homeodomain PF00046.29 CDJ84945.1 - 3.9e-16 58.7 1.2 8.7e-16 57.5 0.6 2.0 2 0 0 2 2 2 1 Homeodomain zf-C2H2 PF00096.26 CDJ84945.1 - 4.6e-10 39.4 44.4 0.00085 19.7 7.5 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-met PF12874.7 CDJ84945.1 - 5.5e-06 26.6 29.3 0.0008 19.7 4.0 4.6 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDJ84945.1 - 1.1e-05 25.6 27.5 0.0063 16.8 2.0 4.5 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CDJ84945.1 - 1.2e-05 25.7 37.6 0.13 13.1 0.6 5.0 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDJ84945.1 - 8.5e-05 22.4 33.4 0.0022 17.9 1.1 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger Homeobox_KN PF05920.11 CDJ84945.1 - 0.0012 18.8 0.9 0.0031 17.4 0.0 2.1 2 0 0 2 2 2 1 Homeobox KN domain DUF4479 PF14794.6 CDJ84945.1 - 0.15 11.9 0.1 8 6.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) DUF2197 PF09963.9 CDJ84945.1 - 0.27 11.5 4.2 0.42 10.9 0.6 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) zf_UBZ PF18439.1 CDJ84945.1 - 0.32 10.6 17.3 6.1 6.5 0.7 4.4 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 CDJ84945.1 - 0.69 10.7 11.8 0.58 10.9 1.4 3.4 2 1 1 3 3 3 0 zinc-ribbon family Yippee-Mis18 PF03226.14 CDJ84945.1 - 2.2 8.5 6.0 7.9 6.7 2.4 2.8 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Vps39_2 PF10367.9 CDJ84945.1 - 4.7 7.7 8.3 9.1 6.8 0.0 4.2 3 1 1 4 4 4 0 Vacuolar sorting protein 39 domain 2 EMC3_TMCO1 PF01956.16 CDJ84946.1 - 0.21 11.3 0.0 0.24 11.1 0.0 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Ank_2 PF12796.7 CDJ84947.1 - 2.5e-16 60.0 0.2 8e-09 36.0 0.0 4.3 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ84947.1 - 1.8e-10 41.1 3.5 6.3e-07 29.8 0.0 4.8 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ84947.1 - 2.7e-10 39.6 2.0 0.99 10.2 0.0 6.6 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 CDJ84947.1 - 1.8e-08 34.5 1.1 0.011 16.0 0.0 5.4 6 1 1 7 7 7 2 Ankyrin repeats (many copies) Ank PF00023.30 CDJ84947.1 - 0.00013 22.3 0.7 0.59 10.7 0.0 4.6 5 0 0 5 5 5 1 Ankyrin repeat Adhes-Ig_like PF09085.10 CDJ84947.1 - 0.13 12.4 0.0 2.7 8.1 0.0 2.4 2 0 0 2 2 2 0 Adhesion molecule, immunoglobulin-like WD40 PF00400.32 CDJ84948.1 - 3.2e-48 160.7 22.2 2.4e-09 37.6 0.1 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ84948.1 - 1.5e-28 98.9 1.8 2.7e-05 24.4 0.0 7.1 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDJ84948.1 - 5.8e-10 39.4 0.1 5.7e-05 23.1 0.0 3.3 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 CDJ84948.1 - 1.5e-08 34.3 0.2 2.8e-08 33.4 0.2 1.5 1 0 0 1 1 1 1 LisH Coatomer_WDAD PF04053.14 CDJ84948.1 - 2e-05 23.9 0.0 0.24 10.4 0.0 3.2 1 1 2 3 3 3 2 Coatomer WD associated region WD40_like PF17005.5 CDJ84948.1 - 5.8e-05 22.6 0.0 0.46 9.8 0.0 3.3 2 1 1 3 3 3 2 WD40-like domain Nbas_N PF15492.6 CDJ84948.1 - 0.00076 18.9 0.2 0.092 12.1 0.0 3.0 2 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 CDJ84948.1 - 0.0027 16.4 0.8 0.57 8.8 0.0 3.5 2 1 2 4 4 4 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CDJ84948.1 - 0.028 13.4 0.0 16 4.3 0.0 3.6 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CitX PF03802.14 CDJ84950.1 - 0.044 13.5 0.3 3.2 7.5 0.0 2.3 1 1 1 2 2 2 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase FlgM PF04316.13 CDJ84950.1 - 0.074 13.4 0.4 0.17 12.2 0.1 1.7 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM HTH_26 PF13443.6 CDJ84950.1 - 0.081 13.4 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_32 PF13565.6 CDJ84950.1 - 0.36 11.5 3.9 0.16 12.6 0.7 1.9 2 1 0 2 2 2 0 Homeodomain-like domain RVT_1 PF00078.27 CDJ84951.1 - 1.1e-06 28.3 0.0 2.6e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ECH_1 PF00378.20 CDJ84954.1 - 1.3e-10 41.1 0.0 1.5e-10 40.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CDJ84954.1 - 7.5e-10 38.8 0.0 9.1e-10 38.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CDJ84955.1 - 4.5e-36 124.5 0.5 5.1e-36 124.3 0.5 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CDJ84955.1 - 9.9e-11 41.7 0.1 1.5e-10 41.1 0.1 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase RII_binding_1 PF10522.9 CDJ84956.1 - 0.31 11.4 1.3 5.1 7.6 0.2 3.0 2 0 0 2 2 2 0 RII binding domain DUF2070 PF09843.9 CDJ84957.1 - 0.12 10.7 0.0 0.14 10.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) FtsJ PF01728.19 CDJ84958.1 - 2.1e-19 70.3 0.0 3.4e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase zf-CCHC_2 PF13696.6 CDJ84958.1 - 0.1 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Zinc knuckle TTR-52 PF01060.23 CDJ84959.1 - 3.9e-24 85.2 0.0 4.9e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Transthyretin-like family bMG3 PF11974.8 CDJ84959.1 - 0.025 14.6 0.0 0.033 14.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain TTR-52 PF01060.23 CDJ84960.1 - 1.7e-25 89.5 0.0 2.2e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Transthyretin-like family bMG3 PF11974.8 CDJ84960.1 - 0.043 13.9 0.0 0.059 13.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain ERCC4 PF02732.15 CDJ84961.1 - 0.022 15.0 0.2 0.088 13.0 0.0 1.9 2 0 0 2 2 2 0 ERCC4 domain PIP5K PF01504.18 CDJ84964.1 - 2.6e-90 302.4 0.0 3.7e-90 301.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase LRR_9 PF14580.6 CDJ84965.1 - 3.1e-12 46.4 0.0 3.9e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CDJ84965.1 - 2.5e-10 40.4 1.6 1e-05 25.8 0.3 3.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ84965.1 - 2.8e-06 27.0 4.1 5.9e-06 26.0 0.7 2.8 2 1 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.6 CDJ84965.1 - 6e-05 22.8 0.5 5.2 7.4 0.1 4.3 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 CDJ84965.1 - 0.15 12.7 1.6 1.1e+02 4.0 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat Glypican PF01153.19 CDJ84965.1 - 0.77 8.5 3.0 1 8.1 3.0 1.1 1 0 0 1 1 1 0 Glypican MBD_C PF14048.6 CDJ84966.1 - 5.6e-19 68.6 0.2 1.1e-18 67.7 0.2 1.5 1 0 0 1 1 1 1 C-terminal domain of methyl-CpG binding protein 2 and 3 MBDa PF16564.5 CDJ84966.1 - 8.9e-07 29.0 0.9 8.9e-07 29.0 0.9 2.5 3 1 0 3 3 3 1 p55-binding region of Methyl-CpG-binding domain proteins MBD AT_hook PF02178.19 CDJ84966.1 - 1 9.4 5.0 1.7 8.7 2.2 2.7 2 0 0 2 2 2 0 AT hook motif Forkhead PF00250.18 CDJ84967.1 - 1.5e-26 92.5 0.1 3.1e-26 91.4 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain FOXO-TAD PF16676.5 CDJ84967.1 - 0.55 10.7 4.5 0.51 10.8 0.5 2.4 2 0 0 2 2 2 0 Transactivation domain of FOXO protein family DUF915 PF06028.11 CDJ84969.1 - 0.1 11.9 0.0 0.33 10.3 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) CBF PF03914.17 CDJ84970.1 - 9.9e-22 77.8 0.3 9.9e-22 77.8 0.3 2.7 3 0 0 3 3 3 1 CBF/Mak21 family TBP PF00352.21 CDJ84971.1 - 1.1e-64 214.4 0.1 5.2e-32 109.6 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 CDJ84971.1 - 0.00014 21.9 0.0 0.31 11.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Hexapep PF00132.24 CDJ84971.1 - 0.0015 18.1 0.0 0.0052 16.5 0.0 2.0 1 0 0 1 1 1 1 Bacterial transferase hexapeptide (six repeats) TPR_2 PF07719.17 CDJ84972.1 - 4.1e-23 79.6 19.6 2.2e-06 27.3 0.0 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ84972.1 - 7.2e-19 66.9 7.2 0.0045 17.7 0.0 7.5 4 1 3 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ84972.1 - 5.2e-16 57.7 20.2 2.3e-05 24.0 0.0 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ84972.1 - 1.2e-15 56.3 15.3 0.00018 21.5 0.5 7.5 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ84972.1 - 3.6e-15 56.2 6.8 1.5e-07 31.8 0.0 5.6 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ84972.1 - 1.7e-11 44.6 4.3 3.6e-06 27.5 0.0 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ84972.1 - 5.2e-10 39.0 1.0 0.00025 21.2 0.0 5.7 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ84972.1 - 7.4e-10 38.8 3.2 0.065 13.9 0.0 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ84972.1 - 3.3e-09 36.9 7.8 4.5e-05 23.7 0.1 5.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ84972.1 - 3.8e-08 32.9 0.0 0.00076 19.1 0.0 4.5 3 1 1 4 4 4 2 TPR repeat ANAPC3 PF12895.7 CDJ84972.1 - 4.6e-08 33.2 7.5 7.8e-05 22.8 1.1 5.4 5 1 1 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CDJ84972.1 - 1.2e-06 28.1 7.6 1.6 9.0 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ84972.1 - 1.9e-06 27.9 2.9 0.00096 19.3 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 CDJ84972.1 - 1.9e-05 24.1 3.7 0.0053 16.0 0.3 4.2 2 1 2 4 4 4 1 Tetratricopeptide repeat PPR PF01535.20 CDJ84972.1 - 2.6e-05 24.2 2.8 0.12 12.7 0.1 4.6 6 0 0 6 6 3 2 PPR repeat ChAPs PF09295.10 CDJ84972.1 - 4.8e-05 22.5 1.2 0.00022 20.4 1.2 1.9 1 1 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) SPOB_a PF14689.6 CDJ84972.1 - 0.00099 18.8 2.7 4 7.2 0.1 4.5 4 1 0 4 4 4 1 Sensor_kinase_SpoOB-type, alpha-helical domain SHNi-TPR PF10516.9 CDJ84972.1 - 0.0016 17.8 0.0 2.5 7.6 0.0 3.9 4 0 0 4 4 4 1 SHNi-TPR TPR_10 PF13374.6 CDJ84972.1 - 0.0032 17.3 5.7 0.046 13.6 0.2 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ84972.1 - 0.028 14.5 9.1 17 5.6 0.1 5.5 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Clathrin PF00637.20 CDJ84972.1 - 0.038 13.9 0.0 0.038 13.9 0.0 3.9 3 2 1 4 4 4 0 Region in Clathrin and VPS V-ATPase_H_C PF11698.8 CDJ84972.1 - 0.081 13.0 0.3 0.96 9.6 0.1 2.6 2 0 0 2 2 2 0 V-ATPase subunit H FeS_assembly_P PF01883.19 CDJ84973.1 - 2.2e-13 50.2 0.0 4.3e-13 49.2 0.0 1.5 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein MOLO1 PF17175.4 CDJ84973.1 - 0.11 12.6 0.1 0.16 12.1 0.1 1.2 1 0 0 1 1 1 0 Modulator of levamisole receptor-1 Cas_Cas7 PF05107.12 CDJ84973.1 - 0.12 11.9 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cas7 Pam16 PF03656.13 CDJ84974.1 - 4.2e-48 162.6 1.1 8e-48 161.6 1.1 1.4 1 0 0 1 1 1 1 Pam16 FtsJ PF01728.19 CDJ84974.1 - 5.7e-32 111.2 0.0 9.6e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase COMM_domain PF07258.14 CDJ84974.1 - 2.5e-08 33.9 0.7 5.2e-08 32.9 0.7 1.6 1 0 0 1 1 1 1 COMM domain Methyltransf_23 PF13489.6 CDJ84974.1 - 0.029 14.2 0.0 0.064 13.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ84974.1 - 0.067 13.9 0.1 1.3 9.8 0.0 3.0 2 1 0 2 2 2 0 Methyltransferase domain FPP PF05911.11 CDJ84976.1 - 0.0002 19.7 19.6 0.00022 19.6 19.6 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Lebercilin PF15619.6 CDJ84976.1 - 0.00022 20.9 24.9 0.00038 20.2 24.9 1.4 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 CDJ84976.1 - 0.00077 18.9 25.1 0.002 17.5 25.1 1.6 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 CDJ84976.1 - 0.0019 18.5 30.5 0.0091 16.2 11.8 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Sec2p PF06428.11 CDJ84976.1 - 0.004 17.1 6.6 0.004 17.1 6.6 3.0 2 1 1 3 3 3 1 GDP/GTP exchange factor Sec2p HMMR_N PF15905.5 CDJ84976.1 - 0.021 14.3 22.7 0.031 13.8 22.7 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF4201 PF13870.6 CDJ84976.1 - 0.13 12.0 19.4 0.23 11.2 17.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) APG6_N PF17675.1 CDJ84976.1 - 0.18 12.3 32.7 0.096 13.2 12.6 2.5 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF1664 PF07889.12 CDJ84976.1 - 0.19 11.7 12.3 0.058 13.4 4.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3138 PF11336.8 CDJ84976.1 - 0.22 10.1 3.6 0.31 9.6 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Nup54 PF13874.6 CDJ84976.1 - 0.26 11.4 21.0 2.9 8.0 20.7 2.2 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Fib_alpha PF08702.10 CDJ84976.1 - 0.35 11.0 12.5 0.11 12.7 8.3 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SKA1 PF07160.12 CDJ84976.1 - 0.81 9.5 14.4 0.92 9.3 13.6 1.5 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 ADIP PF11559.8 CDJ84976.1 - 0.95 9.5 25.8 3.9 7.5 10.4 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 CDJ84976.1 - 0.98 8.7 21.9 1.2 8.5 20.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 CDJ84976.1 - 1.1 8.0 9.3 1.2 8.0 9.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein NPV_P10 PF05531.12 CDJ84976.1 - 2 8.9 8.6 21 5.7 1.1 3.6 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4472 PF14739.6 CDJ84976.1 - 2.4 8.9 20.5 1 10.2 10.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Golgin_A5 PF09787.9 CDJ84976.1 - 2.6 7.4 26.1 18 4.7 26.4 1.9 1 1 0 1 1 1 0 Golgin subfamily A member 5 SlyX PF04102.12 CDJ84976.1 - 2.9 8.6 26.0 15 6.3 9.8 3.8 1 1 2 3 3 3 0 SlyX Csm1_N PF18504.1 CDJ84976.1 - 3.7 7.9 18.6 2.5 8.5 5.0 3.1 2 2 1 3 3 3 0 Csm1 N-terminal domain T3SS_needle_E PF08988.10 CDJ84976.1 - 4.1 7.6 19.5 0.17 12.1 8.5 3.1 2 2 1 3 3 3 0 Type III secretion system, cytoplasmic E component of needle DUF2730 PF10805.8 CDJ84976.1 - 4.2 7.5 10.4 4.7 7.4 2.2 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) Spc7 PF08317.11 CDJ84976.1 - 4.3 6.1 27.5 0.051 12.5 10.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein CREPT PF16566.5 CDJ84976.1 - 4.3 7.5 22.1 0.14 12.3 7.1 2.3 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Tropomyosin_1 PF12718.7 CDJ84976.1 - 4.4 7.5 26.5 5.2e+02 0.7 26.5 2.4 1 1 0 1 1 1 0 Tropomyosin like GIT_CC PF16559.5 CDJ84976.1 - 5.3 7.0 12.9 1.5 8.7 4.3 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor V_ATPase_I PF01496.19 CDJ84976.1 - 5.4 4.8 11.6 7.7 4.3 11.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fez1 PF06818.15 CDJ84976.1 - 7.1 7.0 24.0 2.9 8.3 20.2 1.9 1 1 1 2 2 2 0 Fez1 DUF2968 PF11180.8 CDJ84976.1 - 7.1 6.2 28.1 0.17 11.5 10.9 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2968) Phage_GPO PF05929.11 CDJ84976.1 - 7.6 6.1 19.2 0.18 11.4 6.7 2.3 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Cnn_1N PF07989.11 CDJ84976.1 - 9 6.5 17.4 0.12 12.6 3.0 3.0 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Occludin_ELL PF07303.13 CDJ84976.1 - 9.9 7.0 11.8 2.6 8.8 3.7 2.7 1 1 0 2 2 2 0 Occludin homology domain tRNA-synt_2d PF01409.20 CDJ84978.1 - 3.8e-91 304.9 0.0 5.2e-91 304.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD1 PF18552.1 CDJ84978.1 - 1.1e-16 60.3 1.4 1.1e-16 60.3 1.4 1.7 2 0 0 2 2 2 1 PheRS DNA binding domain 1 PheRS_DBD3 PF18553.1 CDJ84978.1 - 2.1e-15 56.8 0.2 6.7e-15 55.1 0.0 2.0 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 CDJ84978.1 - 2.8e-07 30.2 0.0 2.3e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 CDJ84978.1 - 3.2e-05 23.8 1.3 8.4e-05 22.5 1.3 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2 PF00152.20 CDJ84978.1 - 4.3e-05 22.7 1.2 0.0023 17.0 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 CDJ84978.1 - 0.013 15.5 0.0 0.031 14.2 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) RNB PF00773.19 CDJ84979.1 - 5e-70 236.4 0.0 7.4e-70 235.8 0.0 1.3 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 CDJ84979.1 - 6e-25 87.1 0.0 1.8e-24 85.5 0.0 1.9 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 CDJ84979.1 - 2.1e-05 24.3 0.0 5.2e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 CDJ84979.1 - 0.016 15.4 0.0 3.9 7.7 0.0 2.9 3 0 0 3 3 3 0 Cold shock domain OB_RNB PF08206.11 CDJ84979.1 - 0.025 14.2 0.1 0.061 13.0 0.1 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain ExbD PF02472.16 CDJ84979.1 - 0.098 12.8 0.5 0.41 10.8 0.5 2.1 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Metallophos PF00149.28 CDJ84981.1 - 5e-05 23.9 0.0 7.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HMG_CoA_synt_C PF08540.10 CDJ84982.1 - 2.6e-76 256.9 0.6 2.6e-76 256.9 0.6 1.5 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 CDJ84982.1 - 5.7e-70 234.7 0.2 8.7e-70 234.1 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal TPR_14 PF13428.6 CDJ84983.1 - 0.0058 17.4 4.3 3.7 8.6 0.1 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 CDJ84983.1 - 0.0063 15.8 1.0 0.87 8.7 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat Suf PF05843.14 CDJ84983.1 - 0.028 14.4 6.2 2.3 8.2 2.2 3.1 1 1 1 3 3 3 0 Suppressor of forked protein (Suf) CDC50 PF03381.15 CDJ84983.1 - 0.17 11.4 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family TPR_14 PF13428.6 CDJ84984.1 - 0.071 14.0 0.3 0.18 12.7 0.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat SCVP PF17619.2 CDJ84985.1 - 1.4e-18 67.5 0.1 1.6e-18 67.4 0.1 1.0 1 0 0 1 1 1 1 Secreted clade V proteins CX PF01705.19 CDJ84986.1 - 0.0024 18.4 3.2 0.0024 18.4 3.2 4.1 3 1 1 4 4 4 2 CX module HR_lesion PF05514.11 CDJ84986.1 - 1.1 9.4 4.0 11 6.2 0.1 2.4 2 0 0 2 2 2 0 HR-like lesion-inducing PrgI PF12666.7 CDJ84986.1 - 4.6 8.0 5.6 2 9.2 0.6 2.7 3 0 0 3 3 3 0 PrgI family protein RVT_1 PF00078.27 CDJ84987.1 - 1.8e-13 50.6 0.0 3.3e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) P4Ha_N PF08336.11 CDJ84989.1 - 8.1e-33 113.3 0.8 1.6e-32 112.4 0.8 1.5 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 CDJ84989.1 - 8.3e-16 58.7 0.2 1.5e-15 57.8 0.2 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 CDJ84989.1 - 2e-09 37.8 0.0 4.5e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 CDJ84989.1 - 4.3e-05 23.3 0.4 0.00053 19.9 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ84989.1 - 0.0077 16.3 0.1 0.02 14.9 0.1 1.7 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 CDJ84989.1 - 0.13 12.6 0.1 0.35 11.2 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat P4Ha_N PF08336.11 CDJ84990.1 - 2.8e-34 118.0 1.4 3.6e-34 117.7 1.4 1.2 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TPR_2 PF07719.17 CDJ84990.1 - 0.021 14.9 0.5 0.66 10.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ84990.1 - 0.022 15.0 0.1 0.69 10.2 0.1 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Rnk_N PF14760.6 CDJ84990.1 - 0.046 14.2 0.2 0.19 12.3 0.0 2.1 2 0 0 2 2 2 0 Rnk N-terminus SPO22 PF08631.10 CDJ84990.1 - 0.085 12.3 0.3 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like Casc1 PF12366.8 CDJ84990.1 - 0.1 12.1 2.0 0.14 11.7 2.0 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 DUF3837 PF12939.7 CDJ84990.1 - 0.31 11.5 1.7 1.8 9.0 1.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3837) MCD PF05292.11 CDJ84991.1 - 3.2e-92 308.8 0.0 4e-92 308.4 0.0 1.1 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain MCD_N PF17408.2 CDJ84991.1 - 8.5e-15 54.7 0.0 2.1e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase N-terminal domain Glyco_hydro_63 PF03200.16 CDJ84992.1 - 2.7e-172 573.9 0.6 7.4e-172 572.5 1.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 CDJ84992.1 - 5.3e-24 85.6 0.9 9.9e-24 84.7 0.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain GDE_C PF06202.14 CDJ84992.1 - 0.031 13.2 0.0 0.054 12.4 0.0 1.4 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Histone PF00125.24 CDJ84993.1 - 0.00011 22.6 0.0 0.00014 22.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 FA_hydroxylase PF04116.13 CDJ84994.1 - 4.7e-20 72.3 16.5 4.7e-20 72.3 16.5 1.9 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily 7tm_1 PF00001.21 CDJ84995.1 - 8.2e-27 94.2 19.8 8.2e-27 94.2 19.8 1.5 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Zona_pellucida PF00100.23 CDJ84996.1 - 3.1e-13 50.1 5.1 4.7e-13 49.5 5.1 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain STE3 PF02076.15 CDJ84996.1 - 0.038 13.2 0.7 0.061 12.5 0.7 1.2 1 0 0 1 1 1 0 Pheromone A receptor ABG_transport PF03806.13 CDJ84996.1 - 0.16 10.1 0.0 0.23 9.6 0.0 1.1 1 0 0 1 1 1 0 AbgT putative transporter family Reprolysin PF01421.19 CDJ84998.1 - 3.8e-19 69.4 0.1 6.8e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 CDJ84998.1 - 2.6e-17 63.1 11.1 3.8e-16 59.4 2.0 4.9 4 2 0 4 4 4 2 ADAM cysteine-rich domain TSP_1 PF00090.19 CDJ84998.1 - 7.5e-17 61.3 38.5 1.1e-09 38.4 8.1 6.6 7 1 0 7 7 7 3 Thrombospondin type 1 domain Reprolysin_5 PF13688.6 CDJ84998.1 - 4.3e-11 43.3 0.7 7.6e-11 42.5 0.7 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Pep_M12B_propep PF01562.19 CDJ84998.1 - 1.2e-06 28.8 0.1 3.2e-06 27.4 0.1 1.8 2 0 0 2 2 2 1 Reprolysin family propeptide Reprolysin_3 PF13582.6 CDJ84998.1 - 2.5e-06 28.0 0.3 4.2e-06 27.3 0.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 CDJ84998.1 - 0.00013 21.9 0.3 0.00027 20.9 0.3 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CDJ84998.1 - 0.00081 19.1 0.2 0.0014 18.3 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 CDJ84998.1 - 0.2 10.6 0.3 0.33 9.9 0.3 1.2 1 0 0 1 1 1 0 Peptidase M66 YgaB PF14182.6 CDJ84999.1 - 0.077 13.4 0.1 0.2 12.0 0.0 1.7 2 0 0 2 2 2 0 YgaB-like protein Ion_trans_2 PF07885.16 CDJ85001.1 - 1.4e-21 76.2 25.8 5.5e-14 51.9 2.8 3.2 3 1 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CDJ85001.1 - 0.00038 19.8 0.5 0.00038 19.8 0.5 2.4 2 1 0 2 2 2 1 Ion transport protein Ribosomal_S5 PF00333.20 CDJ85002.1 - 0.15 12.1 0.6 0.32 11.0 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein S5, N-terminal domain Cadherin PF00028.17 CDJ85003.1 - 5.9e-30 103.6 6.2 1.4e-13 51.1 0.2 7.8 8 0 0 8 8 8 5 Cadherin domain Cadherin_2 PF08266.12 CDJ85003.1 - 0.019 14.8 0.1 0.1 12.4 0.1 2.3 1 0 0 1 1 1 0 Cadherin-like Cadherin_pro PF08758.11 CDJ85003.1 - 0.038 14.2 0.5 2.8 8.2 0.0 4.2 5 0 0 5 5 5 0 Cadherin prodomain like Patched PF02460.18 CDJ85004.1 - 1.2e-36 126.2 5.7 1.3e-36 126.0 5.7 1.0 1 0 0 1 1 1 1 Patched family PilX_N PF14341.6 CDJ85004.1 - 0.93 9.5 0.1 0.93 9.5 0.1 2.6 3 1 0 3 3 3 0 PilX N-terminal AA_permease PF00324.21 CDJ85005.1 - 8.4e-58 196.1 28.6 1.4e-42 145.9 5.4 2.0 2 0 0 2 2 2 2 Amino acid permease Asp PF00026.23 CDJ85006.1 - 2e-70 237.8 0.3 2.3e-70 237.5 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ85006.1 - 3.8e-07 30.5 4.3 6.5e-06 26.5 4.2 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ85006.1 - 3e-06 27.1 0.2 1.6e-05 24.8 0.2 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.23 CDJ85007.1 - 1.5e-78 264.4 0.1 1.7e-78 264.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ85007.1 - 5.4e-07 30.0 8.7 3.7e-06 27.3 7.2 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ85007.1 - 7.5e-06 25.8 0.9 3e-05 23.8 0.0 2.4 2 2 0 2 2 2 1 Xylanase inhibitor C-terminal Asp PF00026.23 CDJ85008.1 - 1.2e-15 57.8 0.1 2.8e-11 43.4 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ85008.1 - 0.0037 17.5 0.4 0.0097 16.2 0.3 1.7 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Phosphodiest PF01663.22 CDJ85009.1 - 1.3e-65 222.4 0.0 1.7e-65 221.9 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CDJ85009.1 - 0.12 11.7 0.0 14 4.9 0.0 2.3 2 0 0 2 2 2 0 Sulfatase CDT1 PF08839.11 CDJ85012.1 - 3.5e-48 164.2 1.9 1.9e-46 158.6 0.3 2.7 2 0 0 2 2 2 2 DNA replication factor CDT1 like CDT1_C PF16679.5 CDJ85012.1 - 8.7e-16 58.1 1.1 8.7e-16 58.1 1.1 2.7 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain MAP PF03642.13 CDJ85012.1 - 0.022 15.1 0.1 0.43 10.9 0.0 2.6 2 0 0 2 2 2 0 MAP domain ADH_zinc_N_2 PF13602.6 CDJ85013.1 - 1.6e-15 58.3 0.0 2.6e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDJ85013.1 - 6.8e-11 42.0 0.0 1.3e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDJ85013.1 - 2.7e-07 30.6 0.1 5.8e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 CDJ85013.1 - 0.07 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AAA PF00004.29 CDJ85014.1 - 3.6e-42 143.9 0.1 8.8e-42 142.7 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CDJ85014.1 - 2.7e-20 72.0 0.2 6.8e-20 70.8 0.2 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CDJ85014.1 - 7.7e-10 38.4 0.4 1.7e-09 37.3 0.4 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CDJ85014.1 - 2e-06 27.8 3.2 4.2e-06 26.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDJ85014.1 - 8.6e-06 26.2 0.3 0.003 18.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CDJ85014.1 - 1.3e-05 25.0 0.1 3.8e-05 23.5 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CDJ85014.1 - 2.6e-05 24.4 0.1 0.00015 22.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDJ85014.1 - 0.00013 22.3 0.2 0.0096 16.2 0.0 2.7 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 CDJ85014.1 - 0.0013 18.0 0.0 0.0022 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 CDJ85014.1 - 0.0016 17.9 0.2 0.0046 16.4 0.1 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CDJ85014.1 - 0.0071 16.9 0.4 0.023 15.2 0.0 2.3 2 2 0 2 2 1 1 AAA domain AAA_7 PF12775.7 CDJ85014.1 - 0.0097 15.4 0.0 0.023 14.2 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region PhoH PF02562.16 CDJ85014.1 - 0.012 15.1 0.1 0.1 12.1 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.6 CDJ85014.1 - 0.012 15.8 0.0 0.037 14.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CDJ85014.1 - 0.016 14.9 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 CDJ85014.1 - 0.017 14.7 0.5 0.1 12.1 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 CDJ85014.1 - 0.018 14.7 0.3 0.05 13.3 0.3 1.8 1 1 0 1 1 1 0 AAA domain TolA_bind_tri PF16331.5 CDJ85014.1 - 0.02 15.0 2.2 0.064 13.3 0.4 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation AAA_11 PF13086.6 CDJ85014.1 - 0.024 14.4 0.4 0.27 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 CDJ85014.1 - 0.032 13.6 0.3 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 KaiC CPT PF07931.12 CDJ85014.1 - 0.043 13.6 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein RNA_helicase PF00910.22 CDJ85014.1 - 0.046 14.1 0.0 0.098 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 CDJ85014.1 - 0.048 12.8 0.0 0.087 12.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain ABC_tran PF00005.27 CDJ85014.1 - 0.063 13.8 0.2 0.6 10.6 0.0 2.4 2 1 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 CDJ85014.1 - 0.065 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain JIP_LZII PF16471.5 CDJ85014.1 - 0.072 13.3 2.5 0.18 12.0 2.5 1.7 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II NACHT PF05729.12 CDJ85014.1 - 0.079 12.9 0.4 0.31 11.0 0.1 2.0 2 0 0 2 2 2 0 NACHT domain AAA_3 PF07726.11 CDJ85014.1 - 0.087 12.7 0.0 0.32 10.9 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CDJ85014.1 - 0.09 12.5 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CDJ85014.1 - 0.1 11.7 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 CDJ85014.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CDJ85014.1 - 0.12 12.7 1.3 0.2 12.0 0.1 2.0 2 1 0 2 2 1 0 AAA domain TsaE PF02367.17 CDJ85014.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mito_carr PF00153.27 CDJ85015.1 - 4.3e-40 135.6 1.3 1.6e-14 53.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Colicin_V PF02674.16 CDJ85015.1 - 0.013 15.5 0.7 0.072 13.1 0.0 2.2 3 0 0 3 3 3 0 Colicin V production protein Mito_carr PF00153.27 CDJ85016.1 - 3.2e-48 161.6 2.0 4.9e-16 58.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L13 PF00572.18 CDJ85017.1 - 2.8e-36 124.5 0.2 3.7e-36 124.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Recep_L_domain PF01030.24 CDJ85018.1 - 8.4e-13 48.4 9.7 1e-10 41.7 0.3 3.9 3 1 0 3 3 3 2 Receptor L domain Flavi_propep PF01570.17 CDJ85018.1 - 0.17 11.8 0.3 0.53 10.3 0.3 1.8 1 0 0 1 1 1 0 Flavivirus polyprotein propeptide Pkinase PF00069.25 CDJ85019.1 - 1.7e-23 83.4 0.1 2e-18 66.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain HTH_48 PF17906.1 CDJ85019.1 - 7.2e-12 45.2 0.4 1.3e-11 44.4 0.4 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase Pkinase_Tyr PF07714.17 CDJ85019.1 - 2.2e-11 43.6 0.0 1.2e-09 37.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ85019.1 - 6.3e-08 31.8 0.0 9.5e-08 31.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Transposase_1 PF01359.18 CDJ85019.1 - 0.00011 21.9 0.1 0.00026 20.8 0.1 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_24 PF13412.6 CDJ85019.1 - 0.0052 16.3 0.3 0.019 14.5 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding APH PF01636.23 CDJ85019.1 - 0.006 16.5 0.0 0.026 14.4 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family HTH_Tnp_IS630 PF01710.16 CDJ85019.1 - 0.0062 16.6 0.2 0.0062 16.6 0.2 2.2 2 0 0 2 2 2 1 Transposase Kdo PF06293.14 CDJ85019.1 - 0.019 14.3 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HTH_32 PF13565.6 CDJ85019.1 - 0.061 13.9 0.0 0.28 11.8 0.0 2.2 1 1 0 1 1 1 0 Homeodomain-like domain HTH_AsnC-type PF13404.6 CDJ85019.1 - 0.2 11.5 0.6 0.57 10.1 0.0 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain RVT_1 PF00078.27 CDJ85020.1 - 2e-23 83.1 0.0 3.1e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FKBP_C PF00254.28 CDJ85021.1 - 3.1e-09 37.0 0.0 4.9e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase HMG_box_2 PF09011.10 CDJ85022.1 - 7e-17 61.8 15.9 2e-12 47.5 0.4 3.4 2 1 1 3 3 3 2 HMG-box domain HMG_box PF00505.19 CDJ85022.1 - 8.9e-13 48.5 20.8 7.2e-10 39.1 1.6 3.7 2 1 1 3 3 3 2 HMG (high mobility group) box Aldedh PF00171.22 CDJ85022.1 - 0.033 12.7 2.5 0.37 9.3 0.0 2.1 2 0 0 2 2 2 0 Aldehyde dehydrogenase family DUF2582 PF10771.9 CDJ85022.1 - 0.08 13.1 1.8 0.43 10.8 1.8 2.2 1 1 0 1 1 1 0 Winged helix-turn-helix domain (DUF2582) DUF4872 PF16169.5 CDJ85022.1 - 0.094 12.5 1.0 2.8 7.7 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4872) DUF3106 PF11304.8 CDJ85022.1 - 0.27 11.7 12.9 2.8 8.5 8.5 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) YABBY PF04690.13 CDJ85022.1 - 0.99 9.9 6.8 0.086 13.4 2.0 1.7 2 0 0 2 2 2 0 YABBY protein tRNA-synt_1 PF00133.22 CDJ85023.1 - 7.7e-222 737.8 0.0 1.4e-221 737.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDJ85023.1 - 3.4e-24 85.5 0.0 6.2e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CDJ85023.1 - 3.1e-11 42.7 0.1 0.014 14.2 0.0 3.5 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CDJ85023.1 - 0.014 14.8 0.0 0.039 13.3 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Beta-lactamase PF00144.24 CDJ85024.1 - 8.1e-69 232.4 0.0 9.8e-69 232.1 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase DUF727 PF05303.12 CDJ85025.1 - 8.9e-32 109.3 0.0 1.3e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF727) Colicin_Pyocin PF01320.18 CDJ85025.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein An_peroxidase PF03098.15 CDJ85026.1 - 1.1e-46 159.5 0.0 1.2e-19 70.4 0.0 4.2 1 1 3 4 4 4 4 Animal haem peroxidase CENP-X PF09415.10 CDJ85026.1 - 0.062 13.6 0.2 0.16 12.3 0.2 1.7 1 0 0 1 1 1 0 CENP-S associating Centromere protein X An_peroxidase PF03098.15 CDJ85027.1 - 6.3e-144 480.4 0.0 8.3e-144 480.0 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase NAD_binding_6 PF08030.12 CDJ85027.1 - 2e-26 93.0 0.0 3.5e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CDJ85027.1 - 3.1e-16 59.4 0.0 8.4e-16 58.0 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 CDJ85027.1 - 1.1e-15 57.9 12.2 1.1e-15 57.9 12.2 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component EF-hand_7 PF13499.6 CDJ85027.1 - 5.8e-06 26.7 0.2 0.00029 21.2 0.2 3.2 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 CDJ85027.1 - 0.00028 20.6 0.1 2.6 8.2 0.0 4.6 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 CDJ85027.1 - 0.013 15.0 0.0 6.3 6.6 0.0 3.4 3 0 0 3 3 3 0 EF hand DUF2600 PF10776.9 CDJ85027.1 - 0.083 11.8 0.0 0.29 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2600) Haspin_kinase PF12330.8 CDJ85028.1 - 5.6e-59 199.9 0.0 9.1e-59 199.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CDJ85028.1 - 0.038 13.9 0.0 0.6 10.0 0.0 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.25 CDJ85028.1 - 0.08 12.3 0.0 8.7 5.6 0.0 2.4 2 0 0 2 2 2 0 Protein kinase domain Pkinase PF00069.25 CDJ85029.1 - 1.1e-24 87.2 0.2 2.5e-24 86.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ85029.1 - 3.9e-12 46.0 2.7 6.8e-12 45.2 0.1 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CDJ85029.1 - 0.0035 17.3 0.0 2.4 8.0 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 CDJ85029.1 - 0.0046 16.0 0.1 0.0069 15.4 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase DDE_Tnp_1_6 PF13751.6 CDJ85029.1 - 0.025 14.8 1.3 1.8 8.8 0.0 2.7 2 1 0 2 2 2 0 Transposase DDE domain Pkinase_fungal PF17667.1 CDJ85029.1 - 0.025 13.3 3.9 0.0097 14.7 0.8 2.0 1 1 1 2 2 2 0 Fungal protein kinase Ribosomal_L6e PF01159.19 CDJ85029.1 - 0.045 14.3 1.7 0.045 14.3 1.7 2.2 2 0 0 2 2 2 0 Ribosomal protein L6e IL22 PF14565.6 CDJ85029.1 - 0.088 13.1 1.8 0.21 11.9 1.8 1.6 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor SR-25 PF10500.9 CDJ85029.1 - 0.26 10.8 15.5 0.073 12.7 3.5 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Herpes_LMP1 PF05297.11 CDJ85029.1 - 8.2 5.5 10.1 12 5.0 10.1 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Hexokinase_2 PF03727.16 CDJ85030.1 - 1.9e-67 227.2 0.0 2.8e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CDJ85030.1 - 1.6e-65 220.7 0.0 2.9e-65 219.9 0.0 1.4 1 0 0 1 1 1 1 Hexokinase HTH_DeoR PF08220.12 CDJ85030.1 - 0.026 14.3 0.0 0.074 12.8 0.0 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Hexokinase_2 PF03727.16 CDJ85031.1 - 1e-67 228.1 0.0 1.5e-67 227.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CDJ85031.1 - 1e-64 218.2 0.0 1.8e-64 217.4 0.0 1.4 1 0 0 1 1 1 1 Hexokinase T6PP_N PF18572.1 CDJ85032.1 - 0.016 15.0 6.8 0.052 13.4 5.2 2.6 2 1 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DUF3626 PF12294.8 CDJ85032.1 - 0.026 13.6 0.3 0.049 12.7 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3626) Acyl-CoA_dh_1 PF00441.24 CDJ85034.1 - 2.4e-41 141.4 0.1 3.7e-41 140.8 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CDJ85034.1 - 7.9e-37 126.4 0.0 1.6e-36 125.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CDJ85034.1 - 4.9e-26 90.8 0.0 8.5e-26 90.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CDJ85034.1 - 1.4e-11 44.8 0.0 2.4e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AgrD PF05931.11 CDJ85034.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Staphylococcal AgrD protein Ion_trans PF00520.31 CDJ85035.1 - 2.4e-34 118.7 8.7 3.4e-34 118.2 8.7 1.3 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 CDJ85035.1 - 2.1e-20 72.9 0.1 4.2e-20 71.9 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 CDJ85035.1 - 1.1e-12 47.8 7.8 2.6e-12 46.5 7.8 1.7 1 0 0 1 1 1 1 Ion channel Pam17 PF08566.10 CDJ85035.1 - 1.5 8.7 3.7 0.82 9.5 0.4 2.2 3 0 0 3 3 3 0 Mitochondrial import protein Pam17 SieB PF14163.6 CDJ85036.1 - 0.13 11.7 0.1 0.17 11.4 0.1 1.1 1 0 0 1 1 1 0 Super-infection exclusion protein B Cation_efflux PF01545.21 CDJ85037.1 - 2.2e-28 99.3 6.1 2.9e-28 99.0 6.1 1.2 1 0 0 1 1 1 1 Cation efflux family Ribosomal_S4 PF00163.19 CDJ85037.1 - 0.062 14.2 0.0 0.13 13.2 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S4/S9 N-terminal domain Col_cuticle_N PF01484.17 CDJ85037.1 - 7.3 6.7 5.6 1.7e+02 2.4 0.0 2.7 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Astacin PF01400.24 CDJ85038.1 - 3.2e-17 62.8 0.1 5.3e-17 62.1 0.1 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB PF00431.20 CDJ85038.1 - 0.018 15.4 0.1 0.032 14.6 0.1 1.5 1 0 0 1 1 1 0 CUB domain EGF_2 PF07974.13 CDJ85038.1 - 1 9.8 10.4 2.1 8.8 10.4 1.5 1 0 0 1 1 1 0 EGF-like domain Astacin PF01400.24 CDJ85039.1 - 8.2e-57 191.9 0.0 1.2e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 CDJ85039.1 - 0.0004 20.3 0.1 0.035 14.0 0.1 2.6 2 1 1 3 3 3 1 Matrixin Reprolysin_4 PF13583.6 CDJ85039.1 - 0.0027 17.4 0.1 0.0045 16.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CDJ85039.1 - 0.04 14.1 1.0 0.095 12.8 0.4 2.0 2 1 0 2 2 2 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CDJ85039.1 - 0.096 13.2 0.3 0.91 10.1 0.1 2.3 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 CDJ85039.1 - 0.13 11.9 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase DUF4953 PF16313.5 CDJ85039.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Met-zincin THP2 PF09432.10 CDJ85041.1 - 0.14 12.2 0.4 0.31 11.1 0.1 1.6 2 0 0 2 2 2 0 Tho complex subunit THP2 RL10P_insert PF17777.1 CDJ85042.1 - 1.8e-25 88.7 0.0 2.9e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 CDJ85042.1 - 7.2e-19 67.8 0.3 1e-18 67.3 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 zf_UBZ PF18439.1 CDJ85043.1 - 0.05 13.2 1.4 27 4.5 0.0 3.6 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger WD40 PF00400.32 CDJ85044.1 - 7e-57 188.1 15.6 3.5e-08 34.0 0.3 7.9 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ85044.1 - 1.9e-17 63.3 3.0 0.00032 20.9 0.0 5.4 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDJ85044.1 - 4.8e-07 28.8 1.1 0.041 12.5 0.0 4.5 4 1 1 5 5 5 2 Nucleoporin Nup120/160 LisH PF08513.11 CDJ85044.1 - 4.3e-06 26.5 1.1 8.3e-06 25.6 0.1 2.1 2 0 0 2 2 2 1 LisH eIF2A PF08662.11 CDJ85044.1 - 1.3e-05 25.1 0.2 0.0068 16.3 0.0 2.5 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A CALCOCO1 PF07888.11 CDJ85044.1 - 0.025 13.5 1.3 0.046 12.6 1.3 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Nucleoporin_N PF08801.11 CDJ85044.1 - 0.053 12.3 1.0 11 4.6 0.2 3.5 2 1 0 2 2 2 0 Nup133 N terminal like LisH_2 PF16045.5 CDJ85044.1 - 0.14 11.2 0.3 0.31 10.1 0.1 1.7 2 0 0 2 2 2 0 LisH TcpS PF17456.2 CDJ85044.1 - 0.16 12.0 0.4 0.5 10.4 0.1 1.9 2 0 0 2 2 2 0 Toxin-coregulated pilus protein S Chordopox_L2 PF05803.12 CDJ85045.1 - 0.015 15.1 0.5 0.023 14.5 0.5 1.3 1 0 0 1 1 1 0 Chordopoxvirus L2 protein Med21 PF11221.8 CDJ85045.1 - 0.081 13.2 2.0 0.098 12.9 1.3 1.5 1 1 0 1 1 1 0 Subunit 21 of Mediator complex EndoU_bacteria PF14436.6 CDJ85046.1 - 0.072 13.4 0.0 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial EndoU nuclease EF-hand_1 PF00036.32 CDJ85047.1 - 6.9e-16 56.5 7.2 0.009 15.5 0.0 6.4 6 0 0 6 6 6 5 EF hand EF-hand_7 PF13499.6 CDJ85047.1 - 2.5e-13 50.3 8.0 0.00019 21.8 1.7 5.2 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CDJ85047.1 - 5.4e-13 47.7 8.5 0.014 15.2 0.2 6.3 6 0 0 6 6 6 4 EF-hand domain EF-hand_5 PF13202.6 CDJ85047.1 - 1.3e-06 27.7 8.5 0.0024 17.3 0.0 4.9 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 CDJ85047.1 - 4.5e-05 23.2 4.3 0.48 10.3 0.0 4.8 5 0 0 5 5 5 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ85047.1 - 0.00032 21.0 0.9 1.9 8.9 0.1 3.8 2 1 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region AviRa PF11599.8 CDJ85047.1 - 0.049 13.1 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Pkinase PF00069.25 CDJ85048.1 - 2.1e-12 47.0 0.0 3.3e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CDJ85048.1 - 5.4e-06 25.4 0.0 6.9e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 CDJ85048.1 - 0.0063 15.8 0.0 0.0084 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ85048.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Fibrinogen_C PF00147.18 CDJ85049.1 - 2.2e-16 60.3 4.9 4.3e-16 59.4 4.9 1.5 1 1 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DSPc PF00782.20 CDJ85049.1 - 0.081 12.7 0.0 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Collagen PF01391.18 CDJ85051.1 - 3.9e-25 87.4 93.7 8.8e-10 38.2 33.3 4.1 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ85051.1 - 1.5e-08 34.6 0.1 2.5e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain RNase_P_Rpp14 PF01900.19 CDJ85053.1 - 0.0037 17.5 0.0 0.0048 17.1 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family adh_short PF00106.25 CDJ85054.1 - 4.2e-47 160.2 0.0 6e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ85054.1 - 7.2e-25 87.9 0.0 1e-24 87.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ85054.1 - 5.2e-09 36.3 0.0 7.7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 CDJ85054.1 - 6.9e-05 22.2 0.0 0.00011 21.5 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 CDJ85054.1 - 0.055 13.9 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding GDP_Man_Dehyd PF16363.5 CDJ85054.1 - 0.08 12.3 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CDJ85054.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pyr_redox_2 PF07992.14 CDJ85054.1 - 0.15 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3149 PF11346.8 CDJ85054.1 - 0.34 10.6 9.1 0.083 12.5 3.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) DUF2897 PF11446.8 CDJ85054.1 - 1.2 9.1 8.9 2.1 8.3 8.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Glyco_transf_49 PF13896.6 CDJ85055.1 - 3.5e-69 233.7 1.9 4.4e-69 233.3 1.9 1.1 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan DUF1759 PF03564.15 CDJ85057.1 - 2.8e-28 98.7 3.5 4.3e-28 98.1 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Retrotran_gag_2 PF14223.6 CDJ85057.1 - 0.019 14.7 1.5 0.031 13.9 1.5 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Dioxygenase_N PF04444.14 CDJ85057.1 - 0.097 12.5 0.0 0.29 11.0 0.0 1.8 1 1 1 2 2 2 0 Catechol dioxygenase N terminus eIF3g PF12353.8 CDJ85057.1 - 0.32 11.4 13.8 0.099 13.0 1.4 2.8 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G HAD_2 PF13419.6 CDJ85058.1 - 6.8e-17 62.1 0.0 8.7e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDJ85058.1 - 1.7e-10 41.6 0.0 4.6e-10 40.1 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CDJ85058.1 - 5.5e-05 23.7 0.0 7.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CDJ85058.1 - 0.0081 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 CDJ85058.1 - 0.051 13.7 0.0 6.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CDJ85059.1 - 1.8e-23 83.5 0.0 2.4e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDJ85059.1 - 2.2e-11 44.5 0.0 4.9e-10 40.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CDJ85059.1 - 5.4e-05 23.2 0.0 9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 CDJ85059.1 - 0.00028 21.4 0.0 0.00046 20.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CDJ85059.1 - 0.012 15.7 0.0 0.37 10.9 0.0 2.5 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase NT5C PF06941.12 CDJ85059.1 - 0.04 13.8 0.0 0.09 12.6 0.0 1.6 1 1 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) zf-U11-48K PF05253.12 CDJ85060.1 - 2.1e-20 72.2 28.4 9.2e-06 25.5 1.3 4.4 4 0 0 4 4 4 4 U11-48K-like CHHC zinc finger DSPc PF00782.20 CDJ85061.1 - 7.4e-19 67.9 0.0 8e-19 67.8 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDJ85061.1 - 0.0047 16.5 0.0 0.0051 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPn PF14671.6 CDJ85061.1 - 0.05 14.0 0.0 0.06 13.8 0.0 1.1 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half Y_phosphatase3 PF13350.6 CDJ85061.1 - 0.062 13.3 0.0 0.062 13.3 0.0 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family Nucleotid_trans PF03407.16 CDJ85063.1 - 5e-39 134.5 0.3 7.4e-39 133.9 0.3 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase CAP PF00188.26 CDJ85064.1 - 2.7e-06 28.2 2.8 1.6e-05 25.8 2.9 2.2 1 1 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ85064.1 - 3.5e-06 27.3 5.6 4.1e-06 27.1 3.7 2.0 1 1 1 2 2 2 1 Ancylostoma-associated secreted protein related SCVP PF17619.2 CDJ85065.1 - 6.4e-24 84.6 2.2 6e-19 68.7 0.6 2.2 2 0 0 2 2 2 2 Secreted clade V proteins RVT_1 PF00078.27 CDJ85066.1 - 2.1e-15 56.9 0.0 3.7e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDJ85066.1 - 1.1e-05 25.3 0.1 4.3e-05 23.4 0.0 2.1 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ85066.1 - 0.0051 16.4 0.5 0.013 15.0 0.0 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family SCVP PF17619.2 CDJ85067.1 - 1.3e-40 138.1 4.3 1.7e-23 83.2 0.3 2.2 2 0 0 2 2 2 2 Secreted clade V proteins TetR_C_8 PF14278.6 CDJ85067.1 - 0.00028 20.9 0.2 0.0014 18.7 0.0 2.0 2 0 0 2 2 2 1 Transcriptional regulator C-terminal region DUF866 PF05907.13 CDJ85067.1 - 0.093 12.6 0.2 0.52 10.2 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF866) cNMP_binding PF00027.29 CDJ85068.1 - 4.6e-18 65.1 0.0 8.6e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 CDJ85068.1 - 7.9e-07 28.6 5.7 1.4e-06 27.7 5.7 1.3 1 0 0 1 1 1 1 Ion transport protein CLZ PF16526.5 CDJ85068.1 - 3.3e-05 24.1 2.6 7.3e-05 23.1 2.6 1.6 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ion_trans_2 PF07885.16 CDJ85068.1 - 6.6 6.8 7.7 0.34 10.9 1.6 2.0 2 0 0 2 2 2 0 Ion channel Thioredoxin_6 PF13848.6 CDJ85069.1 - 2e-09 37.6 0.8 0.00025 21.0 0.4 2.4 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 CDJ85069.1 - 0.016 15.2 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Neur_chan_LBD PF02931.23 CDJ85071.1 - 1.3e-44 152.3 0.2 1.5e-44 152.0 0.2 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain PUF PF00806.19 CDJ85072.1 - 3.8e-42 139.6 4.7 3e-05 23.5 0.0 7.8 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat DUF4452 PF14618.6 CDJ85073.1 - 0.082 12.8 1.3 0.11 12.3 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) DUF4988 PF16378.5 CDJ85073.1 - 0.1 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function wnt PF00110.19 CDJ85074.1 - 3.9e-74 250.0 26.6 4.3e-74 249.9 26.6 1.0 1 0 0 1 1 1 1 wnt family PAP2_C PF14360.6 CDJ85075.1 - 1.7e-21 76.5 8.2 1.7e-21 76.5 8.2 2.7 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 CDJ85075.1 - 3.3e-07 30.1 2.4 3.3e-07 30.1 2.4 2.5 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 CDJ85075.1 - 0.087 12.5 9.7 0.037 13.7 7.1 1.6 1 1 0 1 1 1 0 PAP2 superfamily Exo_endo_phos_2 PF14529.6 CDJ85076.1 - 0.09 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Arfaptin PF06456.13 CDJ85077.1 - 6.4e-46 156.8 12.9 8.1e-45 153.2 8.4 2.0 1 1 1 2 2 2 2 Arfaptin-like domain BAR PF03114.18 CDJ85077.1 - 4.2e-06 26.6 9.5 4.9e-06 26.4 8.9 1.4 1 1 0 1 1 1 1 BAR domain Integrin_beta PF00362.18 CDJ85077.1 - 0.0032 17.2 0.4 0.0055 16.4 0.4 1.4 1 0 0 1 1 1 1 Integrin beta chain VWA domain TPR_18 PF13512.6 CDJ85077.1 - 0.0079 16.3 0.1 0.067 13.3 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat ACCA PF03255.14 CDJ85077.1 - 0.053 13.4 2.0 0.08 12.8 0.2 2.1 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit FCH PF00611.23 CDJ85077.1 - 0.11 12.8 1.6 2 8.8 0.8 2.7 2 1 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Occludin_ELL PF07303.13 CDJ85077.1 - 5.6 7.7 10.3 2 9.2 0.3 3.5 3 1 0 3 3 3 0 Occludin homology domain Ras PF00071.22 CDJ85078.1 - 1e-45 155.2 0.1 1.2e-45 155.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ85078.1 - 7.1e-14 52.1 0.0 1.2e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ85078.1 - 5e-07 29.3 0.1 6e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDJ85078.1 - 2.2e-05 24.1 0.1 3.3e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDJ85078.1 - 2.6e-05 24.3 0.0 4.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ85078.1 - 3.1e-05 23.9 0.1 0.0011 18.9 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 CDJ85078.1 - 0.003 17.1 0.1 0.014 14.9 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B ParE_toxin PF05016.15 CDJ85078.1 - 0.14 12.8 0.4 0.25 12.0 0.0 1.7 2 0 0 2 2 2 0 ParE toxin of type II toxin-antitoxin system, parDE EB PF01683.18 CDJ85079.1 - 0.02 15.2 0.5 0.02 15.2 0.5 5.2 1 1 3 4 4 4 0 EB module Nodulin_late PF07127.11 CDJ85079.1 - 0.22 11.9 0.5 0.22 11.9 0.5 5.2 5 1 0 5 5 5 0 Late nodulin protein Dickkopf_N PF04706.12 CDJ85079.1 - 0.25 11.9 0.4 0.25 11.9 0.4 5.0 5 1 1 6 6 6 0 Dickkopf N-terminal cysteine-rich region Methyltransf_23 PF13489.6 CDJ85080.1 - 3.6e-12 46.4 0.0 8.2e-12 45.3 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ85080.1 - 7.3e-12 45.8 0.0 1.5e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ85080.1 - 1.6e-11 44.8 0.2 9.4e-11 42.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ85080.1 - 7.1e-11 42.1 0.0 1.1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ85080.1 - 8.9e-08 32.7 0.0 1.6e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 CDJ85080.1 - 0.00015 21.3 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Rsm22 PF09243.10 CDJ85080.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.3 1 1 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 MTS PF05175.14 CDJ85080.1 - 0.022 14.3 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain DOT1 PF08123.13 CDJ85080.1 - 0.044 13.3 0.0 0.12 11.9 0.0 1.7 1 1 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 CDJ85080.1 - 0.084 12.3 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase TBPIP PF07106.13 CDJ85081.1 - 1.2e-18 66.8 0.3 3e-18 65.5 0.3 1.7 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain FlxA PF14282.6 CDJ85081.1 - 9.1e-06 25.6 3.2 1.5e-05 24.9 3.2 1.3 1 0 0 1 1 1 1 FlxA-like protein LZ3wCH PF18517.1 CDJ85081.1 - 0.00027 21.0 0.2 0.19 11.9 0.0 2.9 2 1 0 2 2 2 1 Leucine zipper with capping helix domain DUF4407 PF14362.6 CDJ85081.1 - 0.00052 19.5 6.8 0.00065 19.1 6.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Syntaxin PF00804.25 CDJ85081.1 - 0.0027 17.4 7.2 0.004 16.9 7.2 1.2 1 0 0 1 1 1 1 Syntaxin Tropomyosin_1 PF12718.7 CDJ85081.1 - 0.0051 17.0 5.5 0.0051 17.0 5.5 1.6 1 1 0 1 1 1 1 Tropomyosin like CLZ PF16526.5 CDJ85081.1 - 0.0056 17.0 3.8 0.7 10.3 0.1 2.9 1 1 2 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 CDJ85081.1 - 0.008 16.6 3.1 0.038 14.5 3.1 2.2 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Syntaxin_2 PF14523.6 CDJ85081.1 - 0.022 15.1 4.1 0.049 14.0 4.1 1.6 1 0 0 1 1 1 0 Syntaxin-like protein DUF5595 PF18077.1 CDJ85081.1 - 0.04 14.0 5.2 0.27 11.3 0.6 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5595) Prefoldin_2 PF01920.20 CDJ85081.1 - 0.045 13.7 6.7 0.29 11.1 0.4 3.1 1 1 2 3 3 3 0 Prefoldin subunit DUF2730 PF10805.8 CDJ85081.1 - 0.047 13.8 0.7 0.11 12.6 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) COG5 PF10392.9 CDJ85081.1 - 0.057 13.6 5.2 0.11 12.6 5.2 1.6 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Atg14 PF10186.9 CDJ85081.1 - 0.072 12.2 7.3 0.093 11.8 7.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 CDJ85081.1 - 0.077 10.9 4.5 0.089 10.7 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Allexi_40kDa PF05549.11 CDJ85081.1 - 0.077 12.5 2.1 0.1 12.1 2.1 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Baculo_PEP_C PF04513.12 CDJ85081.1 - 0.085 12.9 4.8 0.53 10.3 5.0 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.11 CDJ85081.1 - 0.11 13.1 5.1 0.13 12.8 4.1 1.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Lectin_N PF03954.14 CDJ85081.1 - 0.12 12.1 4.3 5.4 6.8 1.0 2.3 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF4988 PF16378.5 CDJ85081.1 - 0.15 11.7 2.8 1.2 8.8 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function Fez1 PF06818.15 CDJ85081.1 - 0.16 12.4 5.8 0.24 11.8 5.8 1.2 1 0 0 1 1 1 0 Fez1 TMPIT PF07851.13 CDJ85081.1 - 0.17 11.1 3.8 0.22 10.7 3.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein TPR_MLP1_2 PF07926.12 CDJ85081.1 - 0.18 11.9 8.1 0.57 10.3 8.1 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein HCMV_UL139 PF12507.8 CDJ85081.1 - 0.19 12.1 3.0 0.27 11.6 1.1 2.1 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein Spectrin PF00435.21 CDJ85081.1 - 0.24 11.9 3.3 9.3 6.8 0.7 2.3 1 1 1 2 2 2 0 Spectrin repeat FlaC_arch PF05377.11 CDJ85081.1 - 0.27 11.7 2.8 1.9 8.9 0.6 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 CDJ85081.1 - 0.32 9.8 9.5 0.55 9.0 9.5 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein SKA2 PF16740.5 CDJ85081.1 - 0.34 10.7 5.0 0.33 10.8 2.5 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Cnn_1N PF07989.11 CDJ85081.1 - 0.36 11.0 4.6 4.4 7.5 0.6 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF5082 PF16888.5 CDJ85081.1 - 0.38 11.0 8.9 0.44 10.8 0.7 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) Matrilin_ccoil PF10393.9 CDJ85081.1 - 0.44 10.4 4.6 3.1 7.7 0.9 2.6 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin CorA PF01544.18 CDJ85081.1 - 0.48 9.7 3.4 0.31 10.3 0.7 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein ZapB PF06005.12 CDJ85081.1 - 0.62 10.6 5.4 8.9 6.8 5.6 2.8 2 1 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 CDJ85081.1 - 0.71 9.7 5.4 5.3 6.9 0.3 2.6 1 1 1 2 2 2 0 Septum formation initiator DUF16 PF01519.16 CDJ85081.1 - 0.92 10.0 5.0 1 9.9 4.0 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 LPP PF04728.13 CDJ85081.1 - 0.97 9.9 6.8 44 4.6 6.3 2.7 1 1 0 1 1 1 0 Lipoprotein leucine-zipper YlqD PF11068.8 CDJ85081.1 - 1 9.7 5.7 8.5 6.8 1.7 2.2 1 1 1 2 2 2 0 YlqD protein Spc24 PF08286.11 CDJ85081.1 - 1.3 9.3 6.6 40 4.5 6.6 2.5 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF2203 PF09969.9 CDJ85081.1 - 1.3 9.7 6.6 3.6 8.3 0.2 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) XhlA PF10779.9 CDJ85081.1 - 2.1 8.6 7.0 9.5 6.5 0.9 2.6 1 1 1 2 2 2 0 Haemolysin XhlA LMBR1 PF04791.16 CDJ85081.1 - 3.9 6.3 4.9 10 4.9 4.8 1.6 1 1 0 1 1 1 0 LMBR1-like membrane protein ABC_tran_CTD PF16326.5 CDJ85081.1 - 5.2 7.4 10.7 8.3 6.7 0.6 2.9 2 1 1 3 3 2 0 ABC transporter C-terminal domain Acetyltransf_13 PF13880.6 CDJ85082.1 - 2.5e-18 65.8 0.0 4.2e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 CDJ85082.1 - 1.2e-10 41.0 0.9 1.9e-10 40.4 0.9 1.3 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Ank_2 PF12796.7 CDJ85083.1 - 2.5e-50 169.0 8.7 2.3e-09 37.7 0.0 8.6 6 3 2 8 8 8 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ85083.1 - 3.1e-40 136.0 15.5 1.7e-07 31.6 0.4 10.7 6 3 5 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ85083.1 - 2e-37 126.8 13.0 1.2e-08 35.0 0.4 11.9 9 3 4 13 13 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ85083.1 - 3.8e-30 100.6 11.2 0.00027 21.1 0.1 11.9 11 0 0 11 11 11 6 Ankyrin repeat Ank PF00023.30 CDJ85083.1 - 1.9e-23 81.8 16.0 0.024 15.1 0.3 10.3 9 0 0 9 9 9 8 Ankyrin repeat Dpy-30 PF05186.13 CDJ85083.1 - 3.4e-10 39.4 0.0 1.1e-09 37.9 0.0 1.9 1 0 0 1 1 1 1 Dpy-30 motif Cytochrom_B562 PF07361.11 CDJ85083.1 - 2.4e-08 34.5 6.2 0.033 14.8 0.0 4.5 4 0 0 4 4 4 3 Cytochrome b562 DUF1843 PF08898.10 CDJ85083.1 - 5.5e-07 30.0 4.3 0.14 12.7 0.1 5.7 6 0 0 6 6 6 2 Domain of unknown function (DUF1843) GATase_7 PF13537.6 CDJ85083.1 - 0.0001 22.2 0.1 1.7 8.6 0.0 5.0 5 0 0 5 5 5 1 Glutamine amidotransferase domain DUF3447 PF11929.8 CDJ85083.1 - 0.022 14.7 0.1 0.33 11.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) Tim44 PF04280.15 CDJ85083.1 - 0.081 13.0 4.5 20 5.3 0.1 4.7 5 0 0 5 5 4 0 Tim44-like domain DNA_pol3_a_NI PF14480.6 CDJ85083.1 - 1.3 9.0 4.0 36 4.4 0.0 3.9 5 0 0 5 5 5 0 DNA polymerase III polC-type N-terminus I RVT_N PF13655.6 CDJ85083.1 - 6.2 7.2 7.9 44 4.4 0.3 4.1 4 0 0 4 4 4 0 N-terminal domain of reverse transcriptase SAPS PF04499.15 CDJ85084.1 - 0.66 8.7 6.3 0.73 8.6 6.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 CDJ85084.1 - 9.3 4.9 6.2 9.7 4.8 6.2 1.1 1 0 0 1 1 1 0 Presenilin Cupin_8 PF13621.6 CDJ85085.1 - 8e-39 133.9 0.0 3.4e-32 112.2 0.0 2.2 1 1 1 2 2 2 2 Cupin-like domain Cupin_4 PF08007.12 CDJ85085.1 - 3.7e-07 29.9 0.0 6.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 CDJ85085.1 - 0.0015 19.0 0.0 0.0036 17.7 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 CDJ85085.1 - 0.093 12.5 0.0 0.96 9.2 0.0 2.3 2 0 0 2 2 2 0 Cupin domain Cupin_1 PF00190.22 CDJ85085.1 - 0.13 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Cupin Collagen PF01391.18 CDJ85086.1 - 2.4e-63 209.7 267.4 9.5e-10 38.1 23.8 10.9 5 3 3 9 9 9 9 Collagen triple helix repeat (20 copies) Presenilin PF01080.17 CDJ85088.1 - 7.6e-67 225.8 6.2 2.8e-37 128.5 0.6 2.0 1 1 1 2 2 2 2 Presenilin Peptidase_A22B PF04258.13 CDJ85088.1 - 0.0097 15.5 0.8 0.028 14.0 0.8 1.8 1 1 0 1 1 1 1 Signal peptide peptidase NiFe_hyd_3_EhaA PF17367.2 CDJ85088.1 - 0.66 10.1 5.8 0.12 12.5 1.4 1.8 2 0 0 2 2 2 0 NiFe-hydrogenase-type-3 Eha complex subunit A ABC2_membrane_2 PF12679.7 CDJ85088.1 - 3.8 6.7 8.2 8.6 5.5 8.2 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein Presenilin PF01080.17 CDJ85090.1 - 1.4e-103 346.8 23.9 1.5e-68 231.4 17.8 3.0 1 1 2 3 3 3 2 Presenilin 7TM_GPCR_Srw PF10324.9 CDJ85091.1 - 4.5e-14 52.5 17.0 5.7e-14 52.1 17.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 CDJ85091.1 - 5.9e-07 29.1 14.9 7.9e-07 28.7 14.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MIG-14_Wnt-bd PF06664.12 CDJ85091.1 - 0.092 11.9 17.9 0.055 12.7 3.1 2.1 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion Recep_L_domain PF01030.24 CDJ85092.1 - 6.4e-15 55.2 0.5 1.4e-08 34.9 0.0 2.3 2 0 0 2 2 2 2 Receptor L domain HSP20 PF00011.21 CDJ85093.1 - 8.6e-21 74.0 0.0 1.2e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ85093.1 - 0.0041 16.6 0.1 0.009 15.6 0.1 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA RRM_1 PF00076.22 CDJ85095.1 - 6.3e-10 38.7 0.0 1.5e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CDJ85095.1 - 0.0023 17.9 2.9 0.0023 17.9 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif Lge1 PF11488.8 CDJ85095.1 - 0.032 14.4 0.2 0.095 12.9 0.2 1.8 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 NCBP3 PF10309.9 CDJ85095.1 - 0.063 13.1 0.0 0.81 9.6 0.0 2.5 1 1 0 1 1 1 0 Nuclear cap-binding protein subunit 3 Nup35_RRM_2 PF14605.6 CDJ85095.1 - 0.077 13.0 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif BRAP2 PF07576.12 CDJ85095.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 BRCA1-associated protein 2 GREB1 PF15782.5 CDJ85095.1 - 0.49 7.5 7.7 0.75 6.8 7.7 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer IU_nuc_hydro PF01156.19 CDJ85096.1 - 1.3e-40 139.8 0.2 1.7e-40 139.5 0.2 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase IU_nuc_hydro PF01156.19 CDJ85097.1 - 2e-65 221.4 0.5 2.4e-65 221.1 0.5 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DM PF00751.18 CDJ85098.1 - 6.9e-13 48.3 6.5 1.2e-12 47.5 6.5 1.3 1 0 0 1 1 1 1 DM DNA binding domain CTD_bind PF04818.13 CDJ85099.1 - 3.3e-12 47.0 0.0 7.7e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Ocnus PF05005.15 CDJ85100.1 - 1.8e-38 131.0 0.0 2e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) Ocnus PF05005.15 CDJ85101.1 - 2.9e-37 127.1 0.8 3.2e-37 126.9 0.8 1.0 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) Eno-Rase_NADH_b PF12242.8 CDJ85101.1 - 0.14 12.0 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Asparaginase_2 PF01112.18 CDJ85102.1 - 8.7e-75 251.6 0.0 1.1e-74 251.2 0.0 1.0 1 0 0 1 1 1 1 Asparaginase Sushi PF00084.20 CDJ85103.1 - 2.7e-14 53.5 5.7 0.00034 21.1 0.3 3.2 3 0 0 3 3 3 3 Sushi repeat (SCR repeat) CC PF04942.14 CDJ85103.1 - 1.8 8.8 12.9 0.97 9.7 0.4 3.3 3 0 0 3 3 3 0 CC domain Lipocalin PF00061.23 CDJ85104.1 - 7.3e-19 68.4 0.6 8e-19 68.3 0.6 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 CDJ85104.1 - 5.1e-08 32.9 0.1 5.4e-08 32.8 0.1 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family TMEM144 PF07857.12 CDJ85105.1 - 1.8e-114 382.2 7.7 5e-114 380.8 7.7 1.6 1 1 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 CDJ85105.1 - 1.3e-09 37.8 12.3 1.6e-07 31.0 4.9 2.4 2 0 0 2 2 2 2 Sugar transport protein Ureide_permease PF07168.11 CDJ85105.1 - 5.2e-08 32.0 2.1 8.2e-07 28.1 2.1 2.0 1 1 0 1 1 1 1 Ureide permease DUF3290 PF11694.8 CDJ85105.1 - 0.056 13.4 0.8 5.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Zip PF02535.22 CDJ85105.1 - 0.064 12.5 0.1 0.064 12.5 0.1 2.3 2 1 1 3 3 3 0 ZIP Zinc transporter DUF2499 PF10693.9 CDJ85105.1 - 0.12 12.7 1.1 0.49 10.7 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2499) DUF2198 PF09964.9 CDJ85105.1 - 4.9 7.3 6.5 0.87 9.7 0.6 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2198) DMT_YdcZ PF04657.13 CDJ85105.1 - 8.7 6.6 22.5 0.17 12.2 7.2 2.7 3 0 0 3 3 3 0 Putative inner membrane exporter, YdcZ Astacin PF01400.24 CDJ85108.1 - 3.6e-17 62.6 0.0 5e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) RasGEF PF00617.19 CDJ85109.1 - 1.4e-42 145.9 2.0 3.1e-42 144.8 0.0 2.3 2 1 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 CDJ85109.1 - 6.1e-11 42.5 0.1 1.9e-10 40.9 0.1 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif Gln-synt_C PF00120.24 CDJ85110.1 - 2.3e-18 66.3 0.0 6e-14 51.8 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain PfkB PF00294.24 CDJ85111.1 - 2.3e-75 253.7 0.1 2.7e-75 253.5 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase PYNP_C PF07831.13 CDJ85111.1 - 0.097 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain CBFD_NFYB_HMF PF00808.23 CDJ85112.1 - 6.8e-25 87.1 0.9 1.2e-24 86.4 0.9 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDJ85112.1 - 0.00042 20.7 2.7 0.0008 19.8 0.0 2.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF2724 PF10893.8 CDJ85112.1 - 0.14 12.0 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) RTX_C PF08339.10 CDJ85112.1 - 0.67 10.0 3.7 1.7 8.7 0.1 2.4 2 0 0 2 2 2 0 RTX C-terminal domain IBN_N PF03810.19 CDJ85113.1 - 0.053 13.4 0.2 0.62 10.0 0.0 2.8 2 1 1 3 3 3 0 Importin-beta N-terminal domain Dzip-like_N PF13815.6 CDJ85114.1 - 3.2e-06 27.1 0.9 3.2e-06 27.1 0.9 1.5 2 0 0 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-C2H2 PF00096.26 CDJ85114.1 - 2.7e-05 24.4 1.0 5e-05 23.5 1.0 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ85114.1 - 0.00029 21.4 1.2 0.00066 20.3 1.2 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDJ85114.1 - 0.0015 18.4 1.4 0.012 15.6 0.5 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger ARS2 PF04959.13 CDJ85114.1 - 0.0081 16.6 0.6 0.0094 16.3 0.6 1.1 1 0 0 1 1 1 1 Arsenite-resistance protein 2 zf-C2H2_3rep PF18868.1 CDJ85114.1 - 0.0091 16.7 0.3 0.021 15.5 0.1 1.7 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf_C2H2_ZHX PF18387.1 CDJ85114.1 - 0.013 15.1 0.1 0.024 14.3 0.1 1.4 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 CDJ85114.1 - 0.031 14.6 1.2 0.051 13.9 0.2 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Mut7-C PF01927.16 CDJ85114.1 - 0.07 13.2 1.0 0.46 10.6 0.1 1.9 1 1 1 2 2 2 0 Mut7-C RNAse domain zf-H2C2_2 PF13465.6 CDJ85114.1 - 0.18 12.3 0.3 0.18 12.3 0.3 2.1 2 0 0 2 2 2 0 Zinc-finger double domain FOXP-CC PF16159.5 CDJ85114.1 - 5 7.8 5.7 25 5.6 0.2 2.2 2 0 0 2 2 2 0 FOXP coiled-coil domain Arf PF00025.21 CDJ85115.1 - 7e-36 123.3 0.0 2.4e-35 121.5 0.0 1.9 3 0 0 3 3 2 1 ADP-ribosylation factor family Roc PF08477.13 CDJ85115.1 - 4.7e-14 52.6 0.0 1.2e-13 51.4 0.0 1.7 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDJ85115.1 - 5.6e-11 42.3 0.0 1.9e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 CDJ85115.1 - 1.9e-09 37.6 0.0 4.5e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CDJ85115.1 - 1.2e-08 34.6 0.0 2.5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Apolipoprotein PF01442.18 CDJ85115.1 - 3.5e-07 30.3 10.1 8.2e-07 29.1 10.0 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain G-alpha PF00503.20 CDJ85115.1 - 4.4e-07 29.4 0.7 0.00064 19.0 0.1 2.9 1 1 2 3 3 3 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CDJ85115.1 - 1e-05 25.0 0.0 2.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_18 PF13238.6 CDJ85115.1 - 1.7e-05 25.4 0.5 0.013 16.1 0.0 3.1 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.27 CDJ85115.1 - 8.5e-05 23.1 0.4 0.00072 20.1 0.0 2.2 2 1 0 2 2 2 1 ABC transporter DUF89 PF01937.19 CDJ85115.1 - 0.00027 20.0 0.7 0.25 10.3 0.0 3.2 2 1 0 3 3 3 1 Protein of unknown function DUF89 Prefoldin_2 PF01920.20 CDJ85115.1 - 0.0053 16.7 0.5 0.56 10.2 0.0 2.3 2 0 0 2 2 2 1 Prefoldin subunit NACHT PF05729.12 CDJ85115.1 - 0.01 15.8 0.2 0.23 11.4 0.0 2.9 3 1 0 3 3 3 0 NACHT domain TsaE PF02367.17 CDJ85115.1 - 0.012 15.6 0.0 0.032 14.2 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 CDJ85115.1 - 0.013 15.8 0.4 0.14 12.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CDJ85115.1 - 0.014 15.6 0.5 0.04 14.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CDJ85115.1 - 0.017 15.0 0.0 0.37 10.7 0.0 2.6 2 1 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 CDJ85115.1 - 0.017 15.6 0.6 1.3 9.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF615 PF04751.14 CDJ85115.1 - 0.029 14.4 2.6 0.084 12.8 2.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF615) AAA_33 PF13671.6 CDJ85115.1 - 0.031 14.4 4.0 0.039 14.1 0.1 2.8 2 2 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CDJ85115.1 - 0.037 14.4 6.3 0.091 13.1 0.0 2.6 2 2 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 CDJ85115.1 - 0.042 13.4 0.1 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 CDJ85115.1 - 0.067 13.6 0.0 0.23 11.9 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) BAR_3_WASP_bdg PF10456.9 CDJ85115.1 - 0.098 12.1 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein AAA_24 PF13479.6 CDJ85115.1 - 0.11 12.2 0.0 0.59 9.8 0.0 2.2 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.12 CDJ85115.1 - 0.11 11.7 0.1 12 5.1 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Syntaxin_2 PF14523.6 CDJ85115.1 - 0.12 12.8 5.6 0.22 11.9 0.4 2.3 1 1 1 2 2 2 0 Syntaxin-like protein Fib_alpha PF08702.10 CDJ85115.1 - 0.15 12.2 1.7 1.3 9.2 0.4 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family V-SNARE PF05008.15 CDJ85115.1 - 0.17 12.3 4.8 2.1 8.8 0.2 2.5 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF155 PF02582.14 CDJ85115.1 - 0.33 11.0 3.0 1.1 9.3 2.9 1.9 1 1 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 HSCB_C PF07743.13 CDJ85115.1 - 0.5 10.9 3.8 5.5 7.6 0.3 2.5 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Exonuc_VII_L PF02601.15 CDJ85115.1 - 0.7 9.4 7.1 1.1 8.8 7.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2205 PF10224.9 CDJ85115.1 - 0.72 9.9 4.1 1 9.4 0.5 2.5 2 0 0 2 2 2 0 Short coiled-coil protein Spc7 PF08317.11 CDJ85115.1 - 0.73 8.7 5.9 1 8.2 5.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FUSC PF04632.12 CDJ85115.1 - 0.75 8.3 6.9 1.1 7.6 6.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DASH_Dad4 PF08650.10 CDJ85115.1 - 2.1 8.4 5.0 6.1 6.9 0.2 3.1 3 0 0 3 3 3 0 DASH complex subunit Dad4 CorA PF01544.18 CDJ85115.1 - 2.4 7.4 8.1 10 5.3 1.7 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein RmuC PF02646.16 CDJ85115.1 - 4.1 6.5 7.0 3.4 6.7 1.5 2.2 1 1 1 2 2 2 0 RmuC family SHQ1 PF04925.15 CDJ85116.1 - 4.2e-53 179.5 0.3 6.3e-53 178.9 0.3 1.2 1 0 0 1 1 1 1 SHQ1 protein Peptidase_C48 PF02902.19 CDJ85117.1 - 1.1e-15 58.1 0.1 3e-15 56.7 0.1 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Acetyltransf_14 PF03421.16 CDJ85117.1 - 0.067 13.3 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase DUF4489 PF14879.6 CDJ85117.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4489) Tyr-DNA_phospho PF06087.12 CDJ85118.1 - 2.2e-96 323.4 0.0 2.6e-96 323.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 CDJ85118.1 - 0.0007 19.5 0.0 0.19 11.6 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CDJ85118.1 - 0.002 18.2 0.2 0.089 13.0 0.0 3.1 3 0 0 3 3 3 1 Phospholipase D Active site motif Kdo PF06293.14 CDJ85119.1 - 3.7e-07 29.7 0.0 4.5e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ85119.1 - 1.4e-05 25.2 0.0 1.4e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CDJ85119.1 - 0.00026 20.4 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.25 CDJ85119.1 - 0.00079 18.9 0.0 0.00099 18.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 CDJ85119.1 - 0.0019 17.8 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 CDJ85119.1 - 0.042 13.1 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Choline_kinase PF01633.20 CDJ85119.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Recep_L_domain PF01030.24 CDJ85120.1 - 1.4e-19 70.3 1.2 5.5e-06 26.5 0.0 3.6 3 1 0 3 3 3 3 Receptor L domain Dzip-like_N PF13815.6 CDJ85121.1 - 3.2e-06 27.1 0.9 3.2e-06 27.1 0.9 1.5 2 0 0 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-C2H2 PF00096.26 CDJ85121.1 - 2.7e-05 24.4 1.0 5e-05 23.5 1.0 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ85121.1 - 0.00029 21.4 1.2 0.00066 20.3 1.2 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDJ85121.1 - 0.0015 18.4 1.4 0.012 15.6 0.5 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger ARS2 PF04959.13 CDJ85121.1 - 0.0081 16.6 0.6 0.0094 16.3 0.6 1.1 1 0 0 1 1 1 1 Arsenite-resistance protein 2 zf-C2H2_3rep PF18868.1 CDJ85121.1 - 0.0091 16.7 0.3 0.021 15.5 0.1 1.7 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf_C2H2_ZHX PF18387.1 CDJ85121.1 - 0.013 15.1 0.1 0.024 14.3 0.1 1.4 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 CDJ85121.1 - 0.031 14.6 1.2 0.051 13.9 0.2 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Mut7-C PF01927.16 CDJ85121.1 - 0.07 13.2 1.0 0.46 10.6 0.1 1.9 1 1 1 2 2 2 0 Mut7-C RNAse domain zf-H2C2_2 PF13465.6 CDJ85121.1 - 0.18 12.3 0.3 0.18 12.3 0.3 2.1 2 0 0 2 2 2 0 Zinc-finger double domain FOXP-CC PF16159.5 CDJ85121.1 - 5 7.8 5.7 25 5.6 0.2 2.2 2 0 0 2 2 2 0 FOXP coiled-coil domain Arf PF00025.21 CDJ85122.1 - 7e-36 123.3 0.0 2.4e-35 121.5 0.0 1.9 3 0 0 3 3 2 1 ADP-ribosylation factor family Roc PF08477.13 CDJ85122.1 - 4.7e-14 52.6 0.0 1.2e-13 51.4 0.0 1.7 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDJ85122.1 - 5.6e-11 42.3 0.0 1.9e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 CDJ85122.1 - 1.9e-09 37.6 0.0 4.5e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CDJ85122.1 - 1.2e-08 34.6 0.0 2.5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Apolipoprotein PF01442.18 CDJ85122.1 - 3.5e-07 30.3 10.1 8.2e-07 29.1 10.0 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain G-alpha PF00503.20 CDJ85122.1 - 4.4e-07 29.4 0.7 0.00064 19.0 0.1 2.9 1 1 2 3 3 3 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CDJ85122.1 - 1e-05 25.0 0.0 2.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_18 PF13238.6 CDJ85122.1 - 1.7e-05 25.4 0.5 0.013 16.1 0.0 3.1 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.27 CDJ85122.1 - 8.5e-05 23.1 0.4 0.00072 20.1 0.0 2.2 2 1 0 2 2 2 1 ABC transporter DUF89 PF01937.19 CDJ85122.1 - 0.00027 20.0 0.7 0.25 10.3 0.0 3.2 2 1 0 3 3 3 1 Protein of unknown function DUF89 Prefoldin_2 PF01920.20 CDJ85122.1 - 0.0053 16.7 0.5 0.56 10.2 0.0 2.3 2 0 0 2 2 2 1 Prefoldin subunit NACHT PF05729.12 CDJ85122.1 - 0.01 15.8 0.2 0.23 11.4 0.0 2.9 3 1 0 3 3 3 0 NACHT domain TsaE PF02367.17 CDJ85122.1 - 0.012 15.6 0.0 0.032 14.2 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 CDJ85122.1 - 0.013 15.8 0.4 0.14 12.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CDJ85122.1 - 0.014 15.6 0.5 0.04 14.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CDJ85122.1 - 0.017 15.0 0.0 0.37 10.7 0.0 2.6 2 1 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 CDJ85122.1 - 0.017 15.6 0.6 1.3 9.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF615 PF04751.14 CDJ85122.1 - 0.029 14.4 2.6 0.084 12.8 2.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF615) AAA_33 PF13671.6 CDJ85122.1 - 0.031 14.4 4.0 0.039 14.1 0.1 2.8 2 2 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CDJ85122.1 - 0.037 14.4 6.3 0.091 13.1 0.0 2.6 2 2 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 CDJ85122.1 - 0.042 13.4 0.1 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 CDJ85122.1 - 0.067 13.6 0.0 0.23 11.9 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) BAR_3_WASP_bdg PF10456.9 CDJ85122.1 - 0.098 12.1 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein AAA_24 PF13479.6 CDJ85122.1 - 0.11 12.2 0.0 0.59 9.8 0.0 2.2 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.12 CDJ85122.1 - 0.11 11.7 0.1 12 5.1 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Syntaxin_2 PF14523.6 CDJ85122.1 - 0.12 12.8 5.6 0.22 11.9 0.4 2.3 1 1 1 2 2 2 0 Syntaxin-like protein Fib_alpha PF08702.10 CDJ85122.1 - 0.15 12.2 1.7 1.3 9.2 0.4 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family V-SNARE PF05008.15 CDJ85122.1 - 0.17 12.3 4.8 2.1 8.8 0.2 2.5 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF155 PF02582.14 CDJ85122.1 - 0.33 11.0 3.0 1.1 9.3 2.9 1.9 1 1 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 HSCB_C PF07743.13 CDJ85122.1 - 0.5 10.9 3.8 5.5 7.6 0.3 2.5 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Exonuc_VII_L PF02601.15 CDJ85122.1 - 0.7 9.4 7.1 1.1 8.8 7.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2205 PF10224.9 CDJ85122.1 - 0.72 9.9 4.1 1 9.4 0.5 2.5 2 0 0 2 2 2 0 Short coiled-coil protein Spc7 PF08317.11 CDJ85122.1 - 0.73 8.7 5.9 1 8.2 5.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FUSC PF04632.12 CDJ85122.1 - 0.75 8.3 6.9 1.1 7.6 6.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DASH_Dad4 PF08650.10 CDJ85122.1 - 2.1 8.4 5.0 6.1 6.9 0.2 3.1 3 0 0 3 3 3 0 DASH complex subunit Dad4 CorA PF01544.18 CDJ85122.1 - 2.4 7.4 8.1 10 5.3 1.7 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein RmuC PF02646.16 CDJ85122.1 - 4.1 6.5 7.0 3.4 6.7 1.5 2.2 1 1 1 2 2 2 0 RmuC family SHQ1 PF04925.15 CDJ85123.1 - 4.2e-53 179.5 0.3 6.3e-53 178.9 0.3 1.2 1 0 0 1 1 1 1 SHQ1 protein Peptidase_C48 PF02902.19 CDJ85124.1 - 1.1e-15 58.1 0.1 3e-15 56.7 0.1 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Acetyltransf_14 PF03421.16 CDJ85124.1 - 0.067 13.3 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase DUF4489 PF14879.6 CDJ85124.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4489) Tyr-DNA_phospho PF06087.12 CDJ85125.1 - 2.2e-96 323.4 0.0 2.6e-96 323.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 CDJ85125.1 - 0.0007 19.5 0.0 0.19 11.6 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CDJ85125.1 - 0.002 18.2 0.2 0.089 13.0 0.0 3.1 3 0 0 3 3 3 1 Phospholipase D Active site motif Kdo PF06293.14 CDJ85126.1 - 3.7e-07 29.7 0.0 4.5e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ85126.1 - 1.4e-05 25.2 0.0 1.4e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CDJ85126.1 - 0.00026 20.4 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.25 CDJ85126.1 - 0.00079 18.9 0.0 0.00099 18.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 CDJ85126.1 - 0.0019 17.8 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 CDJ85126.1 - 0.042 13.1 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Choline_kinase PF01633.20 CDJ85126.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Dzip-like_N PF13815.6 CDJ85127.1 - 3.2e-06 27.1 0.9 3.2e-06 27.1 0.9 1.5 2 0 0 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-C2H2 PF00096.26 CDJ85127.1 - 2.7e-05 24.4 1.0 5e-05 23.5 1.0 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ85127.1 - 0.00029 21.4 1.2 0.00066 20.3 1.2 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDJ85127.1 - 0.0015 18.4 1.4 0.012 15.6 0.5 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger ARS2 PF04959.13 CDJ85127.1 - 0.0081 16.6 0.6 0.0094 16.3 0.6 1.1 1 0 0 1 1 1 1 Arsenite-resistance protein 2 zf-C2H2_3rep PF18868.1 CDJ85127.1 - 0.0091 16.7 0.3 0.021 15.5 0.1 1.7 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf_C2H2_ZHX PF18387.1 CDJ85127.1 - 0.013 15.1 0.1 0.024 14.3 0.1 1.4 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 CDJ85127.1 - 0.031 14.6 1.2 0.051 13.9 0.2 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Mut7-C PF01927.16 CDJ85127.1 - 0.07 13.2 1.0 0.46 10.6 0.1 1.9 1 1 1 2 2 2 0 Mut7-C RNAse domain zf-H2C2_2 PF13465.6 CDJ85127.1 - 0.18 12.3 0.3 0.18 12.3 0.3 2.1 2 0 0 2 2 2 0 Zinc-finger double domain FOXP-CC PF16159.5 CDJ85127.1 - 5 7.8 5.7 25 5.6 0.2 2.2 2 0 0 2 2 2 0 FOXP coiled-coil domain Arf PF00025.21 CDJ85128.1 - 7e-36 123.3 0.0 2.4e-35 121.5 0.0 1.9 3 0 0 3 3 2 1 ADP-ribosylation factor family Roc PF08477.13 CDJ85128.1 - 4.7e-14 52.6 0.0 1.2e-13 51.4 0.0 1.7 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDJ85128.1 - 5.6e-11 42.3 0.0 1.9e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 CDJ85128.1 - 1.9e-09 37.6 0.0 4.5e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CDJ85128.1 - 1.2e-08 34.6 0.0 2.5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Apolipoprotein PF01442.18 CDJ85128.1 - 3.5e-07 30.3 10.1 8.2e-07 29.1 10.0 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain G-alpha PF00503.20 CDJ85128.1 - 4.4e-07 29.4 0.7 0.00064 19.0 0.1 2.9 1 1 2 3 3 3 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CDJ85128.1 - 1e-05 25.0 0.0 2.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_18 PF13238.6 CDJ85128.1 - 1.7e-05 25.4 0.5 0.013 16.1 0.0 3.1 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.27 CDJ85128.1 - 8.5e-05 23.1 0.4 0.00072 20.1 0.0 2.2 2 1 0 2 2 2 1 ABC transporter DUF89 PF01937.19 CDJ85128.1 - 0.00027 20.0 0.7 0.25 10.3 0.0 3.2 2 1 0 3 3 3 1 Protein of unknown function DUF89 Prefoldin_2 PF01920.20 CDJ85128.1 - 0.0053 16.7 0.5 0.56 10.2 0.0 2.3 2 0 0 2 2 2 1 Prefoldin subunit NACHT PF05729.12 CDJ85128.1 - 0.01 15.8 0.2 0.23 11.4 0.0 2.9 3 1 0 3 3 3 0 NACHT domain TsaE PF02367.17 CDJ85128.1 - 0.012 15.6 0.0 0.032 14.2 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 CDJ85128.1 - 0.013 15.8 0.4 0.14 12.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CDJ85128.1 - 0.014 15.6 0.5 0.04 14.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CDJ85128.1 - 0.017 15.0 0.0 0.37 10.7 0.0 2.6 2 1 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 CDJ85128.1 - 0.017 15.6 0.6 1.3 9.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF615 PF04751.14 CDJ85128.1 - 0.029 14.4 2.6 0.084 12.8 2.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF615) AAA_33 PF13671.6 CDJ85128.1 - 0.031 14.4 4.0 0.039 14.1 0.1 2.8 2 2 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CDJ85128.1 - 0.037 14.4 6.3 0.091 13.1 0.0 2.6 2 2 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 CDJ85128.1 - 0.042 13.4 0.1 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 CDJ85128.1 - 0.067 13.6 0.0 0.23 11.9 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) BAR_3_WASP_bdg PF10456.9 CDJ85128.1 - 0.098 12.1 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein AAA_24 PF13479.6 CDJ85128.1 - 0.11 12.2 0.0 0.59 9.8 0.0 2.2 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.12 CDJ85128.1 - 0.11 11.7 0.1 12 5.1 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Syntaxin_2 PF14523.6 CDJ85128.1 - 0.12 12.8 5.6 0.22 11.9 0.4 2.3 1 1 1 2 2 2 0 Syntaxin-like protein Fib_alpha PF08702.10 CDJ85128.1 - 0.15 12.2 1.7 1.3 9.2 0.4 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family V-SNARE PF05008.15 CDJ85128.1 - 0.17 12.3 4.8 2.1 8.8 0.2 2.5 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF155 PF02582.14 CDJ85128.1 - 0.33 11.0 3.0 1.1 9.3 2.9 1.9 1 1 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 HSCB_C PF07743.13 CDJ85128.1 - 0.5 10.9 3.8 5.5 7.6 0.3 2.5 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Exonuc_VII_L PF02601.15 CDJ85128.1 - 0.7 9.4 7.1 1.1 8.8 7.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2205 PF10224.9 CDJ85128.1 - 0.72 9.9 4.1 1 9.4 0.5 2.5 2 0 0 2 2 2 0 Short coiled-coil protein Spc7 PF08317.11 CDJ85128.1 - 0.73 8.7 5.9 1 8.2 5.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FUSC PF04632.12 CDJ85128.1 - 0.75 8.3 6.9 1.1 7.6 6.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DASH_Dad4 PF08650.10 CDJ85128.1 - 2.1 8.4 5.0 6.1 6.9 0.2 3.1 3 0 0 3 3 3 0 DASH complex subunit Dad4 CorA PF01544.18 CDJ85128.1 - 2.4 7.4 8.1 10 5.3 1.7 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein RmuC PF02646.16 CDJ85128.1 - 4.1 6.5 7.0 3.4 6.7 1.5 2.2 1 1 1 2 2 2 0 RmuC family SHQ1 PF04925.15 CDJ85129.1 - 4.2e-53 179.5 0.3 6.3e-53 178.9 0.3 1.2 1 0 0 1 1 1 1 SHQ1 protein Peptidase_C48 PF02902.19 CDJ85130.1 - 1.1e-15 58.1 0.1 3e-15 56.7 0.1 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Acetyltransf_14 PF03421.16 CDJ85130.1 - 0.067 13.3 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase DUF4489 PF14879.6 CDJ85130.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4489) Tyr-DNA_phospho PF06087.12 CDJ85131.1 - 2.2e-96 323.4 0.0 2.6e-96 323.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 CDJ85131.1 - 0.0007 19.5 0.0 0.19 11.6 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CDJ85131.1 - 0.002 18.2 0.2 0.089 13.0 0.0 3.1 3 0 0 3 3 3 1 Phospholipase D Active site motif Kdo PF06293.14 CDJ85132.1 - 3.7e-07 29.7 0.0 4.5e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ85132.1 - 1.4e-05 25.2 0.0 1.4e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CDJ85132.1 - 0.00026 20.4 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.25 CDJ85132.1 - 0.00079 18.9 0.0 0.00099 18.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 CDJ85132.1 - 0.0019 17.8 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 CDJ85132.1 - 0.042 13.1 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Choline_kinase PF01633.20 CDJ85132.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Peptidase_M8 PF01457.16 CDJ85133.1 - 6.6e-58 196.7 3.4 1.1e-57 195.9 3.4 1.3 1 1 0 1 1 1 1 Leishmanolysin RNase_T PF00929.24 CDJ85134.1 - 7.5e-13 49.4 0.0 1.3e-12 48.6 0.0 1.4 1 0 0 1 1 1 1 Exonuclease PAP_assoc PF03828.19 CDJ85135.1 - 5.2e-08 33.0 0.0 1.4e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CDJ85135.1 - 7.9e-05 22.9 0.0 0.00018 21.7 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain TIL PF01826.17 CDJ85136.1 - 4.1e-07 30.2 18.3 5.7e-07 29.7 18.3 1.2 1 0 0 1 1 1 1 Trypsin Inhibitor like cysteine rich domain Serpin PF00079.20 CDJ85137.1 - 6.3e-87 292.3 0.0 7e-87 292.1 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Organ_specific PF10950.8 CDJ85137.1 - 0.14 12.9 0.0 0.25 12.1 0.0 1.4 1 0 0 1 1 1 0 Organ specific protein Ribosomal_L32p PF01783.23 CDJ85138.1 - 1.4 9.3 3.6 16 5.9 0.3 2.7 2 1 0 2 2 2 0 Ribosomal L32p protein family RRM_1 PF00076.22 CDJ85139.1 - 1.6e-28 98.3 0.1 2.2e-15 56.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CDJ85139.1 - 0.00011 22.2 0.4 0.004 17.2 0.2 2.3 2 0 0 2 2 2 1 RNA binding motif Limkain-b1 PF11608.8 CDJ85139.1 - 0.0003 20.8 0.3 0.011 15.8 0.1 2.4 2 0 0 2 2 2 1 Limkain b1 RRM_5 PF13893.6 CDJ85139.1 - 0.0021 17.6 0.0 0.16 11.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDJ85139.1 - 0.0025 17.8 0.0 0.54 10.3 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DbpA PF03880.15 CDJ85139.1 - 0.043 13.8 0.0 12 6.0 0.0 2.3 2 0 0 2 2 2 0 DbpA RNA binding domain RRM_occluded PF16842.5 CDJ85139.1 - 0.044 13.6 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif SOG2 PF10428.9 CDJ85139.1 - 0.098 11.8 18.7 0.12 11.6 18.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein FAM76 PF16046.5 CDJ85139.1 - 0.7 9.2 11.9 1.1 8.6 11.9 1.4 1 0 0 1 1 1 0 FAM76 protein ALMT PF11744.8 CDJ85139.1 - 9.9 4.9 5.5 13 4.5 5.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Peptidase_M22 PF00814.25 CDJ85140.1 - 2.4e-64 217.7 0.0 2.8e-64 217.4 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 CDJ85140.1 - 1.3e-08 34.9 0.5 0.00073 19.3 0.0 3.0 2 1 1 3 3 3 3 Carbamoyltransferase N-terminus RGI1 PF10843.8 CDJ85140.1 - 0.063 12.9 0.3 0.13 11.9 0.3 1.5 1 0 0 1 1 1 0 Respiratory growth induced protein 1 FEZ PF07763.13 CDJ85141.1 - 6.8e-81 271.5 3.8 1e-80 270.9 3.8 1.3 1 0 0 1 1 1 1 FEZ-like protein DUF5102 PF17104.5 CDJ85141.1 - 0.003 17.6 6.6 0.37 10.8 0.1 2.6 2 1 1 3 3 3 2 Domain of unknown function (DUF5102) Lipoprotein_18 PF06804.11 CDJ85141.1 - 0.006 15.7 0.3 0.0096 15.0 0.3 1.2 1 0 0 1 1 1 1 NlpB/DapX lipoprotein CREPT PF16566.5 CDJ85141.1 - 0.026 14.7 2.2 0.059 13.5 2.2 1.6 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour ER PF01133.17 CDJ85141.1 - 0.046 13.7 0.2 0.16 12.0 0.1 2.0 2 0 0 2 2 2 0 Enhancer of rudimentary MCM6_C PF18263.1 CDJ85141.1 - 0.056 13.7 0.7 0.18 12.0 0.7 1.9 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain HAT PF02184.16 CDJ85142.1 - 2.7e-37 126.4 59.5 4.2e-20 71.4 1.8 13.9 13 2 0 13 13 13 7 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 CDJ85142.1 - 1.3e-18 66.1 17.2 0.096 13.6 0.4 11.0 5 3 6 11 11 11 6 Tetratricopeptide repeat Suf PF05843.14 CDJ85142.1 - 2.7e-15 57.1 28.6 1.1e-06 28.9 2.7 5.7 1 1 1 4 4 4 4 Suppressor of forked protein (Suf) TPR_19 PF14559.6 CDJ85142.1 - 5.6e-13 49.2 0.0 0.41 11.2 0.0 6.7 4 2 1 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ85142.1 - 1.6e-11 43.8 0.7 0.0041 17.4 0.0 6.5 6 0 0 6 6 5 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CDJ85142.1 - 2.9e-06 27.3 28.6 0.011 15.8 4.1 6.7 6 2 0 6 6 6 2 Mad3/BUB1 homology region 1 TPR_16 PF13432.6 CDJ85142.1 - 6.1e-06 26.8 0.2 4.6 8.0 0.4 6.2 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ85142.1 - 7.4e-05 22.6 14.0 14 6.1 0.5 8.4 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ85142.1 - 9e-05 22.7 11.4 0.68 10.3 0.0 6.0 5 2 1 6 6 5 2 Tetratricopeptide repeat SNAP PF14938.6 CDJ85142.1 - 0.00049 19.6 3.1 0.8 9.1 0.1 4.2 3 1 1 4 4 4 2 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 CDJ85142.1 - 0.0019 18.7 7.1 59 4.6 0.1 7.4 7 0 0 7 7 7 0 Tetratricopeptide repeat RAB3GAP2_C PF14656.6 CDJ85142.1 - 0.0033 15.7 0.2 0.008 14.5 0.0 1.6 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit C-terminus RPN7 PF10602.9 CDJ85142.1 - 0.011 15.4 1.0 0.033 13.9 0.1 2.2 2 0 0 2 2 2 0 26S proteasome subunit RPN7 ECSIT PF06239.11 CDJ85142.1 - 0.015 14.4 0.1 0.044 12.9 0.1 1.7 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway ANAPC3 PF12895.7 CDJ85142.1 - 0.036 14.3 0.4 6.3 7.1 0.1 4.1 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 U3_assoc_6 PF08640.11 CDJ85142.1 - 0.088 12.9 20.4 0.24 11.5 0.5 6.6 6 1 1 7 7 6 0 U3 small nucleolar RNA-associated protein 6 CKAP2_C PF15297.6 CDJ85142.1 - 0.31 10.1 0.0 0.31 10.1 0.0 3.5 4 1 1 5 5 5 0 Cytoskeleton-associated protein 2 C-terminus Fis1_TPR_C PF14853.6 CDJ85142.1 - 0.56 10.3 6.0 34 4.6 0.2 4.8 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat AF-4 PF05110.13 CDJ85142.1 - 2.3 6.2 12.2 3.4 5.6 12.2 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein UAA PF08449.11 CDJ85143.1 - 1.1e-17 64.2 5.0 1.3e-17 64.0 5.0 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CDJ85143.1 - 2.9e-06 27.5 8.2 3.4e-06 27.3 8.2 1.1 1 0 0 1 1 1 1 EamA-like transporter family TPT PF03151.16 CDJ85143.1 - 0.0013 18.1 1.4 0.0016 17.8 1.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family 7TMR-DISM_7TM PF07695.11 CDJ85143.1 - 0.039 13.9 9.5 0.055 13.4 9.5 1.2 1 0 0 1 1 1 0 7TM diverse intracellular signalling CcmD PF04995.14 CDJ85144.1 - 0.079 13.1 0.3 0.13 12.4 0.3 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) CcmD PF04995.14 CDJ85145.1 - 0.13 12.4 0.3 0.26 11.4 0.3 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) LapA_dom PF06305.11 CDJ85145.1 - 0.45 10.4 1.6 0.91 9.4 1.6 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain NOA36 PF06524.12 CDJ85145.1 - 1.8 7.8 15.3 3.6 6.8 3.1 2.3 2 0 0 2 2 2 0 NOA36 protein PA26 PF04636.13 CDJ85145.1 - 1.8 7.4 12.1 2.6 6.9 12.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) LAP1C PF05609.12 CDJ85145.1 - 3.7 6.5 15.1 5.7 5.9 15.1 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SID-1_RNA_chan PF13965.6 CDJ85145.1 - 3.8 5.8 6.0 66 1.7 6.9 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF4611 PF15387.6 CDJ85145.1 - 6.9 7.0 19.8 0.38 11.0 4.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Mito_carr PF00153.27 CDJ85147.1 - 1.5e-56 188.3 2.6 3.6e-18 65.3 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TTR-52 PF01060.23 CDJ85148.1 - 7.1e-28 97.1 0.0 9.1e-28 96.8 0.0 1.1 1 0 0 1 1 1 1 Transthyretin-like family CarboxypepD_reg PF13620.6 CDJ85148.1 - 0.17 12.2 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Peptidase_S28 PF05577.12 CDJ85149.1 - 3.6e-91 306.1 0.0 4.1e-91 306.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 CDJ85149.1 - 7.5e-07 28.7 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CDJ85149.1 - 1.2e-06 28.2 0.0 2.2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2920 PF11144.8 CDJ85149.1 - 5.1e-05 22.6 0.0 0.00014 21.2 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2920) Abhydrolase_1 PF00561.20 CDJ85149.1 - 0.00011 21.9 0.6 0.00024 20.9 0.3 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ85149.1 - 0.0019 18.8 0.0 0.0027 18.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 CDJ85149.1 - 0.1 12.4 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PALP PF00291.25 CDJ85150.1 - 4.3e-67 226.6 4.6 2.2e-46 158.6 3.1 2.6 2 1 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme PP2C_2 PF13672.6 CDJ85151.1 - 0.047 13.3 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C AAA_12 PF13087.6 CDJ85151.1 - 0.067 12.8 0.0 0.08 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain RVT_1 PF00078.27 CDJ85153.1 - 0.022 14.3 0.0 0.034 13.7 0.0 1.3 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CDJ85154.1 - 0.0008 19.9 0.0 0.0068 16.9 0.0 2.5 1 1 1 2 2 2 1 gag-polyprotein putative aspartyl protease zf-C2H2_10 PF16588.5 CDJ85154.1 - 0.0012 18.5 1.2 0.0028 17.4 1.2 1.6 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC PF00098.23 CDJ85154.1 - 0.013 15.5 1.4 0.031 14.3 1.4 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF2452 PF10504.9 CDJ85154.1 - 0.064 12.7 2.4 0.07 12.6 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2452) SPRY PF00622.28 CDJ85155.1 - 9.3e-14 51.6 0.0 1.4e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 SPRY domain tRNA-synt_1c PF00749.21 CDJ85156.1 - 4.1e-106 354.4 0.0 7e-106 353.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 CDJ85156.1 - 2.8e-42 144.5 0.2 5e-42 143.7 0.2 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.15 CDJ85156.1 - 4.5e-25 88.4 2.4 8.1e-25 87.6 2.4 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Fur_reg_FbpA PF13076.6 CDJ85156.1 - 0.044 13.5 0.0 0.55 10.0 0.0 2.7 2 0 0 2 2 2 0 Fur-regulated basic protein A Imm3 PF14425.6 CDJ85156.1 - 0.14 12.2 0.1 0.35 10.9 0.1 1.6 1 0 0 1 1 1 0 Immunity protein Imm3 Myotub-related PF06602.14 CDJ85157.1 - 6.3e-127 423.3 0.0 8.5e-127 422.9 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FYVE PF01363.21 CDJ85157.1 - 0.00014 22.0 3.4 0.00014 22.0 3.4 2.4 2 0 0 2 2 2 1 FYVE zinc finger Y_phosphatase PF00102.27 CDJ85157.1 - 0.088 12.4 0.0 0.36 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CDJ85157.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Apyrase PF06079.11 CDJ85158.1 - 8.4e-110 366.6 0.4 1.2e-109 366.1 0.4 1.2 1 0 0 1 1 1 1 Apyrase Amino_oxidase PF01593.24 CDJ85158.1 - 1.6e-81 274.9 0.0 5.1e-63 213.9 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ85158.1 - 9.6e-12 45.0 0.5 2.8e-11 43.5 0.1 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain SWIRM PF04433.17 CDJ85158.1 - 6.7e-08 32.8 0.1 1.5e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain Pyr_redox_2 PF07992.14 CDJ85158.1 - 4.7e-07 29.3 0.0 3.3e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CDJ85158.1 - 7.6e-07 29.0 0.3 3.2e-06 27.0 0.1 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 CDJ85158.1 - 3.1e-06 27.7 0.0 8.2e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CDJ85158.1 - 1.7e-05 24.3 0.0 3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 CDJ85158.1 - 7.2e-05 21.7 0.1 0.00082 18.2 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 CDJ85158.1 - 0.00011 21.7 0.1 0.00017 21.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 CDJ85158.1 - 0.00015 21.1 0.0 0.00032 20.0 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 CDJ85158.1 - 0.00024 20.3 0.2 0.00036 19.7 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 CDJ85158.1 - 0.00062 19.1 0.2 0.0012 18.2 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 CDJ85158.1 - 0.014 15.4 0.1 0.81 9.7 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 CDJ85158.1 - 0.017 14.4 0.0 0.15 11.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CDJ85158.1 - 0.035 13.2 0.2 0.057 12.5 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A MCRA PF06100.11 CDJ85158.1 - 0.044 12.6 0.0 0.06 12.1 0.0 1.1 1 0 0 1 1 1 0 MCRA family Lycopene_cycl PF05834.12 CDJ85158.1 - 0.076 12.0 0.2 0.28 10.2 0.2 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein zf-CW PF07496.15 CDJ85158.1 - 0.25 11.4 3.5 0.33 11.0 1.7 2.3 2 0 0 2 2 1 0 CW-type Zinc Finger ANAPC4_WD40 PF12894.7 CDJ85160.1 - 0.083 13.2 0.0 11 6.3 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DHR-2 PF06920.13 CDJ85161.1 - 3.8e-42 144.6 4.0 3e-26 92.2 0.1 2.6 1 1 1 2 2 2 2 Dock homology region 2 TPR_12 PF13424.6 CDJ85161.1 - 0.023 15.0 0.2 1.7 9.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Hemerythrin PF01814.23 CDJ85161.1 - 0.1 13.2 0.2 0.72 10.5 0.0 2.5 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain CARDB PF07705.11 CDJ85161.1 - 0.16 12.3 0.4 0.34 11.2 0.4 1.5 1 0 0 1 1 1 0 CARDB DHR-2 PF06920.13 CDJ85166.1 - 4e-42 144.6 4.0 3e-26 92.2 0.1 2.6 1 1 1 2 2 2 2 Dock homology region 2 CARDB PF07705.11 CDJ85166.1 - 0.16 12.2 0.4 0.34 11.2 0.4 1.5 1 0 0 1 1 1 0 CARDB KOG2701 PF09762.9 CDJ85166.1 - 0.72 10.1 2.8 2.5 8.3 2.8 2.0 1 1 0 1 1 1 0 Coiled-coil domain-containing protein (DUF2037) Lipase_3 PF01764.25 CDJ85172.1 - 4.3e-35 120.7 0.0 6.4e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.20 CDJ85172.1 - 0.0028 17.4 0.1 0.0043 16.7 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PE-PPE PF08237.11 CDJ85172.1 - 0.016 14.8 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain DUF2974 PF11187.8 CDJ85172.1 - 0.02 14.5 0.0 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 CDJ85172.1 - 0.04 14.5 0.0 0.059 14.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDJ85172.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ion_trans_2 PF07885.16 CDJ85173.1 - 3.5e-36 123.0 12.1 3.8e-19 68.4 0.2 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 CDJ85173.1 - 3.1e-06 26.6 5.2 0.012 14.8 0.0 2.7 3 1 0 3 3 3 2 Ion transport protein Peptidase_U4 PF03419.13 CDJ85173.1 - 0.0031 16.8 2.4 0.0062 15.9 2.4 1.4 1 0 0 1 1 1 1 Sporulation factor SpoIIGA IRK PF01007.20 CDJ85173.1 - 0.064 13.1 0.2 6.4 6.6 0.0 2.4 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain SNF2_N PF00176.23 CDJ85174.1 - 6.3e-66 222.5 0.4 1.8e-65 221.0 0.4 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 CDJ85174.1 - 2e-28 98.0 0.8 7.7e-17 60.9 0.3 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain CDH1_2_SANT_HL1 PF18375.1 CDJ85174.1 - 1.9e-22 79.7 0.5 1.9e-22 79.7 0.5 4.7 4 1 1 5 5 5 1 CDH1/2 SANT-Helical linker 1 Helicase_C PF00271.31 CDJ85174.1 - 5.4e-15 55.7 0.0 2.3e-14 53.7 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ85174.1 - 1.2e-09 38.5 0.2 4.8e-09 36.4 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4208 PF13907.6 CDJ85174.1 - 4.9e-08 33.3 0.6 4.9e-08 33.3 0.6 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) SLIDE PF09111.10 CDJ85174.1 - 0.00025 21.1 0.1 0.0027 17.7 0.0 2.8 2 0 0 2 2 2 1 SLIDE Arc PF03869.14 CDJ85174.1 - 0.13 12.2 0.0 0.91 9.4 0.0 2.5 2 0 0 2 2 2 0 Arc-like DNA binding domain SapB_2 PF03489.17 CDJ85175.1 - 2.8e-07 30.5 3.1 2.8e-07 30.5 3.1 2.2 2 0 0 2 2 2 1 Saposin-like type B, region 2 RRT14 PF17075.5 CDJ85175.1 - 0.14 12.2 1.0 0.17 12.0 1.0 1.0 1 0 0 1 1 1 0 Regular of rDNA transcription protein 14 Peptidase_M1 PF01433.20 CDJ85176.1 - 9.2e-85 283.6 1.1 1.5e-84 282.9 1.1 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 CDJ85176.1 - 2.1e-69 234.5 0.0 2.7e-67 227.5 0.0 2.2 2 0 0 2 2 2 2 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CDJ85176.1 - 1.7e-47 162.0 0.3 2.6e-47 161.4 0.3 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain HEAT_2 PF13646.6 CDJ85176.1 - 0.077 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 HEAT repeats Pkinase PF00069.25 CDJ85177.1 - 1.8e-25 89.8 0.0 2.3e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ85177.1 - 4.5e-11 42.5 0.0 5.7e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ85177.1 - 2.1e-05 23.5 0.0 4.4e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDJ85177.1 - 0.00069 19.6 0.3 0.35 10.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family WBP-1 PF11669.8 CDJ85177.1 - 0.0015 19.1 0.2 0.0045 17.6 0.1 1.8 1 1 0 1 1 1 1 WW domain-binding protein 1 Kdo PF06293.14 CDJ85177.1 - 0.011 15.1 0.1 0.047 13.0 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CDJ85178.1 - 6.7e-20 71.6 0.2 8.4e-20 71.2 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CDJ85178.1 - 5.6e-10 38.6 0.1 8.5e-10 38.0 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 CDJ85178.1 - 1.5e-06 27.7 0.0 1.8e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ85178.1 - 0.0004 19.8 0.1 0.00066 19.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ85178.1 - 0.069 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 CDJ85180.1 - 3.7e-38 131.4 0.0 8.2e-27 94.2 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ85180.1 - 4.1e-17 62.3 0.0 9.8e-16 57.8 0.0 2.6 3 0 0 3 3 3 1 Protein tyrosine kinase APH PF01636.23 CDJ85180.1 - 0.00045 20.2 0.1 0.12 12.3 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 CDJ85180.1 - 0.077 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HERV-K_env_2 PF13804.6 CDJ85181.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.5 2 0 0 2 2 2 0 Retro-transcribing viruses envelope glycoprotein Mss4 PF04421.13 CDJ85182.1 - 1.2e-16 60.6 0.1 1.7e-16 60.2 0.1 1.3 1 0 0 1 1 1 1 Mss4 protein fn3 PF00041.21 CDJ85183.1 - 1.8e-17 63.5 4.4 0.0013 19.0 0.1 5.2 4 1 0 4 4 4 4 Fibronectin type III domain WAP PF00095.21 CDJ85183.1 - 3.8e-08 33.6 14.5 3.8e-08 33.6 14.5 2.9 2 1 1 3 3 3 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Cys_box PF17869.1 CDJ85183.1 - 1.9 8.6 14.3 1 9.5 10.0 2.5 1 1 1 2 2 2 0 Anosmin cysteine rich domain Rad1 PF02144.16 CDJ85185.1 - 9.9e-59 198.7 1.0 1.7e-58 197.9 1.0 1.4 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 PCNA_C PF02747.15 CDJ85185.1 - 1.7e-06 28.2 0.2 4e-06 27.0 0.1 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 CDJ85185.1 - 0.00025 20.6 0.2 0.35 10.3 0.2 2.3 1 1 1 2 2 2 2 Rad9 Chrome_Resist PF09828.9 CDJ85185.1 - 0.09 13.2 0.1 3.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Chromate resistance exported protein DUF2935 PF11155.8 CDJ85186.1 - 0.026 14.9 0.0 1.6 9.1 0.0 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Cut12 PF11500.8 CDJ85186.1 - 0.087 12.8 17.8 0.07 13.1 7.3 3.6 2 1 1 3 3 3 0 Spindle pole body formation-associated protein UPF0242 PF06785.11 CDJ85186.1 - 0.29 11.2 29.7 0.15 12.1 14.6 3.2 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin_3 PF13758.6 CDJ85186.1 - 0.5 10.4 7.3 0.59 10.2 0.5 3.4 2 2 1 3 3 3 0 Prefoldin subunit Beach PF02138.18 CDJ85187.1 - 1.3e-36 126.4 0.0 2.8e-36 125.3 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 CDJ85187.1 - 4.5e-06 27.3 6.9 0.00063 20.5 0.1 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_2 PF13360.6 CDJ85187.1 - 0.00011 21.8 0.2 0.00021 21.0 0.2 1.4 1 0 0 1 1 1 1 PQQ-like domain ANAPC4_WD40 PF12894.7 CDJ85187.1 - 0.07 13.4 0.2 1.3 9.4 0.0 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain HeLo PF14479.6 CDJ85188.1 - 0.032 14.0 0.1 0.06 13.2 0.1 1.4 1 0 0 1 1 1 0 Prion-inhibition and propagation MFS_1 PF07690.16 CDJ85189.1 - 1.6e-25 89.8 23.5 1.6e-25 89.8 23.5 1.9 2 1 1 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ85189.1 - 1.6e-25 89.9 18.9 2.2e-25 89.5 18.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Peptidase_U4 PF03419.13 CDJ85189.1 - 0.0041 16.5 8.0 0.0041 16.5 8.0 2.2 2 0 0 2 2 2 1 Sporulation factor SpoIIGA Lectin_C PF00059.21 CDJ85190.1 - 1e-11 45.5 0.5 1.4e-11 45.1 0.5 1.2 1 0 0 1 1 1 1 Lectin C-type domain DUF3048_C PF17479.2 CDJ85190.1 - 0.007 16.7 0.1 1.6 9.2 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3048) C-terminal domain Asp PF00026.23 CDJ85191.1 - 2.8e-44 151.8 0.0 1.1e-32 113.7 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ85191.1 - 9e-13 48.8 2.1 2.8e-11 44.0 2.1 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 CDJ85192.1 - 8.1e-72 242.3 0.0 9.4e-72 242.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ85192.1 - 2.9e-12 47.2 3.3 8.6e-11 42.4 3.1 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ85192.1 - 0.00044 20.0 0.0 0.00098 18.9 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Cyto_heme_lyase PF01265.17 CDJ85193.1 - 2.1e-63 214.6 8.0 2.1e-62 211.3 8.0 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase COX15-CtaA PF02628.15 CDJ85194.1 - 1.5e-102 343.1 7.4 1.7e-102 342.8 7.4 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein SirB PF04247.12 CDJ85194.1 - 0.0016 18.5 0.2 0.0016 18.5 0.2 2.4 3 1 0 3 3 3 1 Invasion gene expression up-regulator, SirB CAP_N PF01213.19 CDJ85195.1 - 0.47 9.9 1.6 0.46 9.9 1.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pyridoxal_deC PF00282.19 CDJ85197.1 - 7.8e-124 413.2 0.0 9.5e-124 412.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 CDJ85197.1 - 3.3e-06 26.6 0.0 5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 CDJ85197.1 - 0.00019 20.5 0.0 0.00039 19.5 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V OKR_DC_1 PF01276.20 CDJ85197.1 - 0.0032 16.3 0.0 0.0047 15.7 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_1_2 PF00155.21 CDJ85197.1 - 0.032 13.4 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II SepSecS PF05889.13 CDJ85197.1 - 0.05 12.3 0.0 0.46 9.1 0.0 2.0 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DegT_DnrJ_EryC1 PF01041.17 CDJ85197.1 - 0.06 12.6 0.0 0.1 11.9 0.0 1.4 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family SNARE_assoc PF09335.11 CDJ85198.1 - 3.1e-08 34.1 0.1 3.1e-08 34.1 0.1 2.5 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF4199 PF13858.6 CDJ85198.1 - 0.22 11.9 4.8 2.4 8.5 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) SAM_2 PF07647.17 CDJ85199.1 - 6.1e-13 48.7 0.0 1.6e-12 47.3 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CDJ85199.1 - 0.042 14.3 0.1 1.3 9.6 0.0 2.8 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) FARP PF01581.16 CDJ85200.1 - 0.0012 19.0 10.1 63 4.8 0.1 5.7 5 0 0 5 5 5 5 FMRFamide related peptide family LAP1C PF05609.12 CDJ85201.1 - 1.1 8.3 8.9 1.1 8.2 8.9 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF148 PF02520.17 CDJ85202.1 - 1.6e-06 28.2 0.1 2.1e-06 27.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 Flagellin_N PF00669.20 CDJ85202.1 - 0.028 14.5 0.9 0.047 13.8 0.9 1.3 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Pkinase_Tyr PF07714.17 CDJ85203.1 - 9.7e-74 247.9 0.0 1.5e-73 247.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ85203.1 - 5.1e-42 144.1 0.0 9.8e-42 143.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDJ85203.1 - 6.1e-06 26.2 0.3 0.00015 21.8 0.3 2.7 1 1 0 1 1 1 1 SH2 domain Clathrin PF00637.20 CDJ85205.1 - 1.6e-10 41.1 8.7 1.2e-09 38.2 0.8 3.3 3 0 0 3 3 3 1 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 CDJ85205.1 - 3.5e-05 23.7 10.7 8.6e-05 22.5 10.7 1.7 1 0 0 1 1 1 1 Zinc-finger zf-rbx1 PF12678.7 CDJ85205.1 - 0.00046 20.4 5.2 0.0012 19.1 5.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CDJ85205.1 - 0.0031 17.8 7.2 0.0096 16.2 7.2 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ85205.1 - 0.0035 17.1 7.7 0.0092 15.8 7.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDJ85205.1 - 0.054 13.6 1.8 0.22 11.6 1.8 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 CDJ85205.1 - 0.21 11.6 6.6 0.72 9.9 6.6 2.0 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 CDJ85205.1 - 0.75 9.7 6.0 1.8 8.5 6.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 CDJ85205.1 - 1 9.7 6.1 3.5 8.0 6.1 2.0 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.6 CDJ85205.1 - 1.1 9.1 4.7 2.8 7.9 4.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CDJ85205.1 - 4.8 6.9 8.1 2 8.1 4.0 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Methyltransf_8 PF05148.15 CDJ85206.1 - 1.5e-56 191.7 0.4 3.4e-56 190.5 0.4 1.6 1 0 0 1 1 1 1 Hypothetical methyltransferase zf-MYND PF01753.18 CDJ85206.1 - 2.5e-11 43.5 12.9 2.5e-11 43.5 12.9 3.1 2 1 0 2 2 2 1 MYND finger Methyltransf_11 PF08241.12 CDJ85206.1 - 2.9e-05 24.6 0.0 9.2e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ85206.1 - 0.0069 17.1 0.0 0.046 14.4 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ85206.1 - 0.016 14.5 0.1 0.059 12.7 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family TetR_C_37 PF18665.1 CDJ85206.1 - 0.13 12.9 0.0 0.27 11.8 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain GTP_EFTU PF00009.27 CDJ85207.1 - 4.1e-43 147.2 0.0 6e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CDJ85207.1 - 1.7e-29 102.4 1.3 5.3e-29 100.8 0.4 2.3 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CDJ85207.1 - 4.1e-07 30.3 0.4 1e-06 29.0 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDJ85207.1 - 0.0036 17.4 0.0 0.019 15.1 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 CDJ85207.1 - 0.042 13.6 0.0 5.3 6.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Complex1_LYR PF05347.15 CDJ85208.1 - 5.2e-11 42.4 0.1 8.3e-11 41.8 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CDJ85208.1 - 0.00013 22.6 1.6 0.00016 22.3 1.6 1.2 1 0 0 1 1 1 1 Complex1_LYR-like RVT_1 PF00078.27 CDJ85209.1 - 1.9e-15 57.0 0.0 3.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ion_trans_2 PF07885.16 CDJ85210.1 - 2.7e-35 120.2 18.2 2e-18 66.1 2.4 3.1 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CDJ85210.1 - 8.5e-09 35.0 6.7 5.4e-05 22.5 0.4 2.1 2 0 0 2 2 2 2 Ion transport protein IRK PF01007.20 CDJ85210.1 - 6.1e-05 22.9 1.0 0.0017 18.1 0.2 2.8 2 0 0 2 2 2 1 Inward rectifier potassium channel transmembrane domain DUF2254 PF10011.9 CDJ85210.1 - 0.00047 19.1 3.6 0.00057 18.8 0.7 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2254) DUF5083 PF16890.5 CDJ85210.1 - 0.04 13.6 0.7 0.2 11.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5083) Pox_A9 PF04835.12 CDJ85210.1 - 6 7.1 9.2 15 5.8 0.3 3.8 3 0 0 3 3 3 0 A9 protein conserved region CBS PF00571.28 CDJ85211.1 - 0.035 14.5 0.0 0.072 13.5 0.0 1.6 1 0 0 1 1 1 0 CBS domain adh_short PF00106.25 CDJ85213.1 - 4.8e-34 117.5 0.0 6.6e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ85213.1 - 7e-23 81.4 0.0 9.2e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ85213.1 - 2.8e-08 33.9 0.0 4.9e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 CDJ85213.1 - 0.049 12.9 0.0 0.53 9.6 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.16 CDJ85213.1 - 0.076 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 CDJ85213.1 - 0.15 11.4 0.0 0.41 10.0 0.0 1.7 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Prenyltrans PF00432.21 CDJ85214.1 - 1.2e-51 172.2 17.9 4e-10 39.2 0.0 6.2 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 CDJ85214.1 - 2.5e-09 36.7 0.1 0.011 14.8 0.0 3.2 1 1 1 3 3 3 3 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 CDJ85214.1 - 0.0061 15.7 0.0 2.9 6.9 0.0 2.9 1 1 2 3 3 3 2 Squalene-hopene cyclase N-terminal domain CBF PF03914.17 CDJ85215.1 - 5.3e-34 117.7 0.3 9e-33 113.7 0.1 2.6 2 0 0 2 2 2 1 CBF/Mak21 family Glyco_hydro_19 PF00182.19 CDJ85216.1 - 2.7e-24 86.4 0.2 2.3e-23 83.3 0.1 2.0 2 0 0 2 2 2 1 Chitinase class I ASPRs PF17641.2 CDJ85217.1 - 0.024 14.9 0.0 0.029 14.6 0.0 1.4 1 1 0 1 1 1 0 Ancylostoma-associated secreted protein related ASPRs PF17641.2 CDJ85218.1 - 0.097 13.0 0.0 0.11 12.7 0.0 1.4 1 1 0 1 1 1 0 Ancylostoma-associated secreted protein related NopRA1 PF16201.5 CDJ85220.1 - 6.8e-40 136.8 4.1 6.8e-40 136.8 4.1 2.6 2 1 1 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 eRF1_2 PF03464.15 CDJ85223.1 - 6.7e-47 159.1 0.1 9.8e-47 158.6 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CDJ85223.1 - 9.1e-40 135.7 0.1 1.8e-39 134.7 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 CDJ85223.1 - 2.5e-18 66.3 0.0 4.2e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 CDJ85223.1 - 2.6e-09 37.5 0.0 3.8e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 CDJ85223.1 - 1.8e-07 31.5 0.0 2.8e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 NAD_binding_1 PF00175.21 CDJ85225.1 - 3.1e-36 124.3 0.0 6.6e-36 123.3 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CDJ85225.1 - 3.8e-34 117.0 0.0 5.6e-34 116.5 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CDJ85225.1 - 1.1e-06 28.8 0.0 2.8e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 CDJ85225.1 - 0.13 12.4 0.0 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain DZR PF12773.7 CDJ85226.1 - 0.0062 16.5 0.3 0.0062 16.5 0.3 2.9 3 0 0 3 3 3 1 Double zinc ribbon zf-ribbon_3 PF13248.6 CDJ85226.1 - 0.013 14.9 0.4 0.2 11.1 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.6 CDJ85226.1 - 0.067 13.1 4.2 0.47 10.4 4.2 2.4 1 1 0 1 1 1 0 Nudix N-terminal zf_UBZ PF18439.1 CDJ85226.1 - 0.098 12.3 2.8 6.1 6.5 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger PknG_rubred PF16919.5 CDJ85226.1 - 0.11 12.7 0.6 0.32 11.2 0.0 2.0 3 0 0 3 3 3 0 Protein kinase G rubredoxin domain zinc-ribbons_6 PF07191.12 CDJ85226.1 - 0.25 11.4 3.7 0.29 11.2 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbons Rubredoxin_2 PF18073.1 CDJ85226.1 - 0.34 10.7 3.3 1.7 8.4 0.1 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-NADH-PPase PF09297.11 CDJ85226.1 - 1.3 8.8 6.7 0.13 12.0 1.3 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-C3HC4_3 PF13920.6 CDJ85226.1 - 2.6 8.0 8.5 5.9 6.8 1.2 3.2 2 2 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) LIM PF00412.22 CDJ85227.1 - 2e-26 91.9 19.2 1.3e-13 51.0 3.9 2.1 2 0 0 2 2 2 2 LIM domain Sgf11 PF08209.11 CDJ85227.1 - 0.18 11.4 0.1 0.18 11.4 0.1 3.0 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) DZR PF12773.7 CDJ85227.1 - 0.18 11.8 20.1 7.8e+02 0.2 20.1 3.3 1 1 0 1 1 1 0 Double zinc ribbon zf_UBZ PF18439.1 CDJ85227.1 - 1.4 8.6 14.9 2.1 8.0 0.1 4.5 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-RING_14 PF17978.1 CDJ85227.1 - 3 8.4 9.9 0.62 10.5 1.7 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain PP2C PF00481.21 CDJ85228.1 - 4.1e-79 265.8 0.1 5.5e-79 265.4 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.13 CDJ85228.1 - 7.5e-07 29.5 0.2 2.7e-06 27.7 0.1 2.0 2 0 0 2 2 2 1 Protein serine/threonine phosphatase 2C, C-terminal domain PP2C_2 PF13672.6 CDJ85228.1 - 2.5e-05 24.0 0.0 0.00019 21.1 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CDJ85228.1 - 0.00011 22.2 0.3 0.0023 17.8 0.1 2.9 3 1 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) Elong_Iki1 PF10483.9 CDJ85228.1 - 0.15 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Elongator subunit Iki1 Flavoprotein PF02441.19 CDJ85229.1 - 2.4e-46 157.4 0.0 2.8e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein ChaC PF04752.12 CDJ85230.1 - 2.2e-52 177.7 0.0 2.5e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein IL17 PF06083.11 CDJ85233.1 - 1.5e-14 54.2 2.0 2.4e-14 53.6 2.0 1.3 1 0 0 1 1 1 1 Interleukin-17 Hist_deacetyl PF00850.19 CDJ85234.1 - 1.8e-33 116.3 0.0 1.5e-20 73.9 0.0 2.1 2 0 0 2 2 2 2 Histone deacetylase domain Clathrin_bdg PF15045.6 CDJ85235.1 - 0.00022 21.1 0.0 0.00074 19.5 0.0 1.9 1 0 0 1 1 1 1 Clathrin-binding box of Aftiphilin, vesicle trafficking DAN PF03045.15 CDJ85237.1 - 2e-25 89.0 6.5 3.2e-25 88.4 6.5 1.3 1 0 0 1 1 1 1 DAN domain Nab1 PF04902.12 CDJ85238.1 - 0.021 15.2 0.2 0.035 14.5 0.0 1.4 1 1 0 1 1 1 0 Conserved region in Nab1 Globin PF00042.22 CDJ85238.1 - 0.081 13.5 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 Globin Polyoma_coat2 PF00761.20 CDJ85238.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 Polyomavirus coat protein IATP PF04568.12 CDJ85238.1 - 0.25 11.8 1.1 0.44 11.0 0.2 1.8 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Pap_E4 PF02711.14 CDJ85239.1 - 2.4 9.2 6.6 9.7 7.2 0.4 2.7 3 0 0 3 3 3 0 E4 protein Glyco_hydro_35 PF01301.19 CDJ85240.1 - 1.4e-113 379.7 0.5 1.8e-113 379.3 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 CDJ85240.1 - 6.5e-08 32.3 0.1 5e-06 26.1 0.1 2.3 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 CDJ85240.1 - 7.9e-05 23.2 1.7 0.0016 19.0 0.1 3.0 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain SDA1 PF05285.12 CDJ85243.1 - 1.2 8.5 15.3 1.4 8.3 15.3 1.2 1 0 0 1 1 1 0 SDA1 SURF2 PF05477.11 CDJ85243.1 - 5.7 6.6 8.4 8.2 6.0 8.4 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CDC45 PF02724.14 CDJ85243.1 - 7.9 4.6 12.1 11 4.1 12.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_A17 PF05380.13 CDJ85245.1 - 4.1e-37 127.7 0.1 8.1e-37 126.7 0.1 1.6 1 0 0 1 1 1 1 Pao retrotransposon peptidase DUF5641 PF18701.1 CDJ85245.1 - 1.1e-17 63.9 0.2 3.6e-17 62.3 0.2 1.9 1 0 0 1 1 1 1 Family of unknown function (DUF5641) Integrase_H2C2 PF17921.1 CDJ85245.1 - 2.9e-14 52.9 0.1 8.2e-14 51.5 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain DUF1758 PF05585.12 CDJ85245.1 - 7.6e-13 48.6 0.0 1.8e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) rve PF00665.26 CDJ85245.1 - 3e-12 46.8 0.0 3.8e-11 43.2 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 CDJ85245.1 - 2.8e-05 23.7 0.0 6.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 CDJ85245.1 - 3.9e-05 23.8 1.0 9.7e-05 22.5 1.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger gag-asp_proteas PF13975.6 CDJ85245.1 - 7.6e-05 23.2 0.0 0.00021 21.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ85245.1 - 8.9e-05 23.1 0.0 0.0002 21.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease rve_3 PF13683.6 CDJ85245.1 - 0.006 16.3 0.0 0.025 14.3 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Vwaint PF14624.6 CDJ85245.1 - 0.053 13.7 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 VWA / Hh protein intein-like PNMA PF14893.6 CDJ85246.1 - 0.03 13.7 0.0 0.067 12.6 0.0 1.5 1 0 0 1 1 1 0 PNMA 7TM_GPCR_Srsx PF10320.9 CDJ85248.1 - 1.3e-19 70.6 2.9 1.5e-19 70.4 2.9 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx CoA_binding_3 PF13727.6 CDJ85248.1 - 0.0017 18.4 0.1 0.0018 18.3 0.1 1.1 1 0 0 1 1 1 1 CoA-binding domain Hirudin PF00713.17 CDJ85249.1 - 0.063 13.6 0.7 0.063 13.6 0.7 2.0 2 0 0 2 2 2 0 Hirudin Tetraspanin PF00335.20 CDJ85250.1 - 1.3e-29 103.5 11.9 1.8e-29 103.1 11.9 1.2 1 0 0 1 1 1 1 Tetraspanin family SUR7 PF06687.12 CDJ85250.1 - 0.0026 17.4 0.8 0.0026 17.4 0.8 2.2 2 0 0 2 2 2 1 SUR7/PalI family PIRT PF15099.6 CDJ85250.1 - 5.3 6.6 5.3 1.1 8.8 0.2 2.2 2 1 0 2 2 2 0 Phosphoinositide-interacting protein family CoA_binding_3 PF13727.6 CDJ85250.1 - 6.8 6.7 7.6 2.3 8.2 1.1 2.3 2 0 0 2 2 2 0 CoA-binding domain Isy1 PF06246.12 CDJ85251.1 - 2.3e-83 279.7 12.2 2.6e-83 279.5 12.2 1.0 1 0 0 1 1 1 1 Isy1-like splicing family Phage_RpbA PF10789.9 CDJ85251.1 - 0.11 12.6 4.7 0.071 13.2 1.9 2.1 2 0 0 2 2 2 0 Phage RNA polymerase binding, RpbA zf-HIT PF04438.16 CDJ85252.1 - 1.8e-10 40.5 9.6 3e-10 39.8 9.6 1.3 1 0 0 1 1 1 1 HIT zinc finger PolC_DP2 PF03833.13 CDJ85252.1 - 0.067 11.0 2.9 0.12 10.3 2.9 1.3 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-MYND PF01753.18 CDJ85252.1 - 0.084 13.0 10.9 0.18 11.9 10.9 1.6 1 0 0 1 1 1 0 MYND finger TPR_2 PF07719.17 CDJ85253.1 - 7.9e-12 44.3 13.7 0.0024 17.9 0.0 7.7 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ85253.1 - 1e-11 44.0 7.7 0.00063 19.8 0.0 8.5 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ85253.1 - 1.2e-10 40.7 6.0 0.0095 15.7 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ85253.1 - 2.5e-09 36.7 3.4 0.0082 15.8 0.2 4.7 4 0 0 4 4 4 3 TPR repeat TPR_19 PF14559.6 CDJ85253.1 - 6.8e-09 36.1 10.3 4e-05 24.0 0.2 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ85253.1 - 7.6e-09 35.8 15.4 0.0054 17.0 0.2 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ85253.1 - 6.9e-08 32.3 5.1 0.017 15.5 0.0 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ85253.1 - 3.5e-07 30.8 2.5 0.013 16.1 0.2 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ85253.1 - 7.6e-07 29.4 5.6 6 7.7 0.0 7.0 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 CDJ85253.1 - 2.5e-06 26.9 0.7 0.0038 16.5 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ85253.1 - 2.7e-06 27.7 7.1 0.035 14.9 0.0 6.2 6 2 1 7 7 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 CDJ85253.1 - 6.3e-06 26.4 0.6 0.53 10.7 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ85253.1 - 0.00053 20.1 2.6 0.18 12.0 0.0 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ85253.1 - 0.0012 18.8 3.3 55 4.1 0.1 7.2 9 0 0 9 9 7 0 Tetratricopeptide repeat NARP1 PF12569.8 CDJ85253.1 - 0.061 12.2 0.1 17 4.1 0.0 3.0 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 CDJ85253.1 - 0.14 12.0 6.5 1.1 9.2 0.2 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ85253.1 - 0.83 9.9 7.2 5.3 7.3 0.1 4.6 4 2 2 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 RNA_pol_Rbc25 PF08292.12 CDJ85254.1 - 4.3e-31 107.8 3.6 1.5e-29 102.8 3.6 2.3 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 CDJ85254.1 - 2.5e-16 59.8 0.1 7.1e-16 58.3 0.1 1.8 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Cyt-b5 PF00173.28 CDJ85255.1 - 2.1e-24 85.4 0.0 3.9e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CH PF00307.31 CDJ85256.1 - 7.5e-51 170.9 0.0 4e-26 91.3 0.0 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain Spectrin PF00435.21 CDJ85256.1 - 5.3e-49 165.1 16.1 7.4e-18 65.0 0.6 4.5 4 0 0 4 4 4 4 Spectrin repeat EFhand_Ca_insen PF08726.10 CDJ85256.1 - 2.2e-24 85.3 0.4 1.9e-23 82.3 0.0 2.7 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 CDJ85256.1 - 1.5e-08 34.3 0.0 4.9e-08 32.7 0.0 1.9 1 0 0 1 1 1 1 CAMSAP CH domain EF-hand_7 PF13499.6 CDJ85256.1 - 0.017 15.6 0.8 0.16 12.5 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain pair Acyltransferase PF01553.21 CDJ85257.1 - 2.6e-09 36.8 0.1 5.5e-09 35.8 0.0 1.5 2 0 0 2 2 2 1 Acyltransferase DAGAT PF03982.13 CDJ85258.1 - 1e-138 461.2 0.1 1.2e-138 461.0 0.1 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransf_C PF16076.5 CDJ85259.1 - 7.9e-11 41.9 0.2 1.3e-10 41.2 0.2 1.3 1 0 0 1 1 1 1 Acyltransferase C-terminus DUF5342 PF17277.2 CDJ85259.1 - 0.081 13.3 0.1 0.081 13.3 0.1 2.0 3 0 0 3 3 3 0 Family of unknown function (DUF5342) DUF1768 PF08719.11 CDJ85260.1 - 8.9e-40 136.6 0.0 1.7e-39 135.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) eIF-5_eIF-2B PF01873.17 CDJ85261.1 - 1.1e-24 86.5 0.2 2.3e-24 85.5 0.2 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 CDJ85261.1 - 4.1e-23 81.3 0.5 1.1e-22 80.0 0.5 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Zn_Tnp_IS1595 PF12760.7 CDJ85261.1 - 0.015 15.3 0.7 0.032 14.2 0.7 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain RXT2_N PF08595.11 CDJ85261.1 - 2.4 8.2 11.7 6.2 6.8 0.9 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal PBP1_TM PF14812.6 CDJ85261.1 - 3.9 7.9 15.0 3.2 8.2 3.3 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2759 PF10958.8 CDJ85262.1 - 0.18 11.6 0.1 0.28 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2759) Innexin PF00876.18 CDJ85263.1 - 2.4e-111 372.4 17.7 2.9e-111 372.2 17.7 1.0 1 0 0 1 1 1 1 Innexin DUF962 PF06127.11 CDJ85263.1 - 0.024 14.7 1.6 0.13 12.3 1.6 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF962) Ank_2 PF12796.7 CDJ85264.1 - 1.6e-41 140.7 0.0 2.4e-15 56.9 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ85264.1 - 1.2e-34 118.2 1.8 1.6e-10 41.3 0.1 5.4 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ85264.1 - 9e-32 108.7 4.0 7.8e-06 26.1 0.0 6.5 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 CDJ85264.1 - 5.8e-29 99.2 2.6 1e-05 25.7 0.0 7.1 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 CDJ85264.1 - 1.7e-28 95.5 1.0 1.9e-05 24.6 0.0 7.6 8 0 0 8 8 8 6 Ankyrin repeat DUF2520 PF10728.9 CDJ85264.1 - 0.072 12.9 1.1 0.25 11.1 0.1 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF2520) SWIRM-assoc_1 PF16495.5 CDJ85266.1 - 8.7e-31 105.7 13.4 8.7e-31 105.7 13.4 1.8 2 0 0 2 2 2 1 SWIRM-associated region 1 SWIRM PF04433.17 CDJ85266.1 - 2.4e-30 104.7 0.0 7.5e-30 103.1 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_3 PF16498.5 CDJ85266.1 - 5.3e-27 93.9 3.7 5.3e-27 93.9 3.7 2.9 3 0 0 3 3 3 1 SWIRM-associated domain at the C-terminal Myb_DNA-binding PF00249.31 CDJ85266.1 - 1.3e-10 41.3 0.0 2.7e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ85266.1 - 3.3e-07 30.4 0.0 9.9e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain MAP65_ASE1 PF03999.12 CDJ85266.1 - 7.4e-06 24.9 1.8 7.4e-06 24.9 1.8 1.9 2 0 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) MAP65_ASE1 PF03999.12 CDJ85267.1 - 3.4e-21 75.6 17.0 8.5e-14 51.2 5.2 2.8 1 1 2 3 3 3 2 Microtubule associated protein (MAP65/ASE1 family) LicD PF04991.13 CDJ85267.1 - 0.1 12.7 3.5 0.21 11.7 0.0 2.6 2 1 1 3 3 3 0 LicD family Phage_GP20 PF06810.11 CDJ85268.1 - 0.21 11.4 1.2 18 5.1 0.0 2.9 3 0 0 3 3 3 0 Phage minor structural protein GP20 CCDC-167 PF15188.6 CDJ85268.1 - 0.32 11.4 3.5 0.73 10.2 0.0 2.9 3 1 0 3 3 3 0 Coiled-coil domain-containing protein 167 CENP-H PF05837.12 CDJ85268.1 - 0.61 10.5 6.0 4.4 7.7 0.1 2.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Lebercilin PF15619.6 CDJ85268.1 - 0.7 9.5 9.4 1.3 8.6 3.0 2.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF641 PF04859.12 CDJ85268.1 - 3.3 8.0 6.0 20 5.6 1.9 3.1 3 1 0 3 3 3 0 Plant protein of unknown function (DUF641) PKcGMP_CC PF16808.5 CDJ85268.1 - 3.9 7.4 7.9 8.7 6.3 0.0 3.0 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TMF_TATA_bd PF12325.8 CDJ85268.1 - 3.9 7.7 10.2 2.9 8.1 5.4 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 CDJ85268.1 - 6.7 5.5 8.1 0.85 8.4 3.8 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 CDJ85268.1 - 10 6.2 13.8 16 5.5 5.9 2.9 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DDE_3 PF13358.6 CDJ85269.1 - 2.6e-12 46.7 0.0 3.9e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease PGM_PMM_IV PF00408.20 CDJ85269.1 - 9.3e-10 38.5 0.1 2e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Nicastrin PF05450.15 CDJ85270.1 - 8.2e-43 146.5 0.0 1.2e-42 146.0 0.0 1.2 1 0 0 1 1 1 1 Nicastrin Ncstrn_small PF18266.1 CDJ85270.1 - 2.3e-31 109.1 0.0 4.1e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 Nicastrin small lobe Peptidase_M28 PF04389.17 CDJ85270.1 - 0.1 12.3 0.1 0.25 11.0 0.0 1.7 2 0 0 2 2 2 0 Peptidase family M28 Pkinase PF00069.25 CDJ85271.1 - 3.8e-56 190.4 0.0 5.2e-56 189.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ85271.1 - 6.6e-22 78.0 0.0 8.8e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ85271.1 - 0.0001 22.3 0.1 0.00018 21.5 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ85271.1 - 0.0027 17.1 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Nop14 PF04147.12 CDJ85271.1 - 2.1 6.5 7.4 2.8 6.1 7.4 1.1 1 0 0 1 1 1 0 Nop14-like family CBS PF00571.28 CDJ85273.1 - 4.1e-08 33.6 1.6 0.001 19.5 0.3 3.3 3 0 0 3 3 3 2 CBS domain DUF2170 PF09938.9 CDJ85273.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) Prefoldin_2 PF01920.20 CDJ85273.1 - 0.044 13.7 8.0 0.71 9.8 0.1 2.4 3 0 0 3 3 3 0 Prefoldin subunit UPF0122 PF04297.14 CDJ85273.1 - 0.64 10.3 4.0 2.8 8.2 0.4 2.3 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like STELLO PF03385.17 CDJ85274.1 - 2.7e-71 240.4 3.8 4.4e-71 239.8 3.8 1.2 1 0 0 1 1 1 1 STELLO glycosyltransferases Clathrin PF00637.20 CDJ85275.1 - 7.6e-10 38.8 1.7 0.00014 21.8 0.2 4.6 3 1 1 4 4 4 2 Region in Clathrin and VPS TPR_7 PF13176.6 CDJ85275.1 - 6.6e-06 25.8 17.2 1.5 9.0 0.1 7.8 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ85275.1 - 0.00012 21.9 27.9 0.97 9.7 0.7 7.6 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ85275.1 - 0.00083 20.0 22.8 41 5.4 0.1 9.0 7 2 0 8 8 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ85275.1 - 0.01 15.7 16.8 2.9 7.9 0.1 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ85275.1 - 0.019 15.3 22.5 5.9 7.3 0.1 7.1 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ85275.1 - 0.027 14.7 14.2 6.5 7.2 0.3 6.6 6 1 1 7 7 6 0 Tetratricopeptide repeat DZR PF12773.7 CDJ85275.1 - 0.035 14.1 9.8 0.17 11.9 6.3 2.6 1 1 1 2 2 2 0 Double zinc ribbon DUF4135 PF13575.6 CDJ85275.1 - 0.084 12.2 0.1 2.9 7.1 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4135) DUF983 PF06170.12 CDJ85275.1 - 0.14 12.6 0.7 0.4 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) RPN7 PF10602.9 CDJ85275.1 - 0.17 11.6 3.6 0.67 9.6 0.4 3.5 2 1 2 4 4 4 0 26S proteasome subunit RPN7 ANAPC3 PF12895.7 CDJ85275.1 - 0.17 12.1 11.9 30 4.9 0.2 5.9 5 1 1 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 Nic96 PF04097.14 CDJ85275.1 - 1.6 7.1 6.4 1.3 7.4 0.0 3.0 4 0 0 4 4 4 0 Nup93/Nic96 Stc1 PF12898.7 CDJ85275.1 - 4.7 7.8 5.6 0.93 10.1 1.7 1.8 2 0 0 2 2 1 0 Stc1 domain TPR_4 PF07721.14 CDJ85275.1 - 7 7.6 16.1 17 6.4 0.1 6.3 7 1 0 7 7 5 0 Tetratricopeptide repeat BRCT_2 PF16589.5 CDJ85276.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Adeno_E3_CR2 PF02439.15 CDJ85276.1 - 0.13 12.1 0.5 0.25 11.1 0.5 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Glyco_hydro_38C PF07748.13 CDJ85277.1 - 1.6e-47 162.4 0.0 2.6e-47 161.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 CDJ85277.1 - 4.7e-23 81.2 0.1 1.6e-22 79.5 0.0 2.0 3 0 0 3 3 3 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 CDJ85277.1 - 4.3e-09 36.4 0.1 1.1e-08 35.1 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain DUF2070 PF09843.9 CDJ85279.1 - 5.4 5.2 8.5 6.4 4.9 8.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ion_trans_2 PF07885.16 CDJ85280.1 - 5e-34 116.1 17.5 2.3e-17 62.7 0.1 2.6 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CDJ85280.1 - 0.0013 18.0 11.9 0.42 9.8 0.1 2.3 2 0 0 2 2 2 2 Ion transport protein FGGY_N PF00370.21 CDJ85280.1 - 0.024 14.2 0.1 0.052 13.1 0.1 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Unstab_antitox PF09720.10 CDJ85280.1 - 0.025 14.6 0.1 2.7 8.1 0.0 2.7 2 0 0 2 2 2 0 Putative addiction module component Unstab_antitox PF09720.10 CDJ85281.1 - 0.049 13.7 0.1 0.85 9.7 0.0 2.4 2 0 0 2 2 2 0 Putative addiction module component FGGY_N PF00370.21 CDJ85281.1 - 0.053 13.1 0.2 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Gp-FAR-1 PF05823.12 CDJ85283.1 - 1.1e-17 64.8 0.1 1.8e-17 64.0 0.1 1.4 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Rop-like PF05082.13 CDJ85283.1 - 0.0094 15.8 0.2 0.097 12.5 0.1 2.2 2 0 0 2 2 2 1 Rop-like MF_alpha_N PF05436.11 CDJ85283.1 - 0.068 13.1 0.8 0.28 11.1 0.0 2.3 3 0 0 3 3 3 0 Mating factor alpha precursor N-terminus Baculo_PEP_C PF04513.12 CDJ85284.1 - 0.0037 17.3 2.7 0.0072 16.4 0.8 2.2 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2130 PF09903.9 CDJ85284.1 - 0.025 13.8 1.0 0.043 13.1 0.2 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) DUF4131 PF13567.6 CDJ85284.1 - 0.07 12.8 0.0 0.07 12.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2165 PF09933.9 CDJ85284.1 - 0.08 13.0 3.1 0.14 12.2 0.9 2.1 2 0 0 2 2 2 0 Predicted small integral membrane protein (DUF2165) Skp1_POZ PF03931.15 CDJ85284.1 - 0.083 13.1 1.2 0.23 11.6 0.4 2.3 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain DUF3810 PF12725.7 CDJ85284.1 - 0.094 12.0 4.4 0.34 10.2 4.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) DUF898 PF05987.13 CDJ85284.1 - 0.16 11.0 3.4 3.4 6.6 0.6 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) DUF2207 PF09972.9 CDJ85284.1 - 0.46 9.2 5.7 0.41 9.3 2.2 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Fib_alpha PF08702.10 CDJ85284.1 - 0.61 10.3 3.1 0.43 10.8 1.2 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ADH_zinc_N PF00107.26 CDJ85286.1 - 9.7e-23 80.6 0.1 1.6e-22 79.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDJ85286.1 - 6.5e-09 36.9 0.0 1e-08 36.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDJ85286.1 - 4.9e-08 32.8 0.1 1e-07 31.8 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TGT PF01702.18 CDJ85287.1 - 4.2e-137 457.0 0.1 5.3e-137 456.7 0.1 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase ELFV_dehydrog PF00208.21 CDJ85288.1 - 8.3e-100 333.5 0.0 1.6e-47 162.3 0.0 3.2 3 0 0 3 3 3 3 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 CDJ85288.1 - 5.9e-68 226.7 0.0 1.2e-55 187.0 0.0 2.4 2 0 0 2 2 2 2 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 CDJ85288.1 - 2.6e-09 36.7 0.1 0.0027 17.1 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 CDJ85288.1 - 1.1e-06 29.0 0.0 0.12 12.8 0.0 2.9 3 0 0 3 3 3 2 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 CDJ85288.1 - 1.3e-05 25.3 0.0 0.29 11.2 0.0 2.6 2 0 0 2 2 2 2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ApbA PF02558.16 CDJ85288.1 - 0.00031 20.4 0.0 0.98 9.1 0.0 2.4 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA DUF4404 PF14357.6 CDJ85288.1 - 0.0011 19.6 0.5 2.9 8.6 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4404) Endonuc-BsobI PF09194.10 CDJ85288.1 - 0.0033 16.7 0.1 2.6 7.2 0.0 2.2 2 0 0 2 2 2 2 Restriction endonuclease BsobI TrkA_N PF02254.18 CDJ85288.1 - 0.0062 16.8 1.6 4.5 7.6 0.1 2.7 2 0 0 2 2 2 2 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 CDJ85288.1 - 0.018 14.6 1.8 4.5 6.8 0.1 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CheB_methylest PF01339.17 CDJ85288.1 - 0.037 13.7 0.0 31 4.3 0.0 3.5 4 0 0 4 4 4 0 CheB methylesterase KR PF08659.10 CDJ85288.1 - 0.099 12.6 0.4 21 5.0 0.1 2.7 2 2 0 2 2 2 0 KR domain Eco57I PF07669.11 CDJ85288.1 - 0.15 12.6 0.0 38 4.9 0.0 2.5 2 0 0 2 2 2 0 Eco57I restriction-modification methylase ThiF PF00899.21 CDJ85288.1 - 0.15 11.4 0.3 20 4.4 0.0 2.4 2 0 0 2 2 2 0 ThiF family Astacin PF01400.24 CDJ85290.1 - 1.6e-27 96.4 1.3 2.8e-25 89.1 0.3 2.6 1 1 1 2 2 2 2 Astacin (Peptidase family M12A) Pkinase_Tyr PF07714.17 CDJ85291.1 - 5e-72 242.3 0.0 6.5e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ85291.1 - 1.1e-44 152.9 0.0 1.5e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDJ85291.1 - 5.6e-10 39.2 0.0 2.4e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 SH2 domain Motile_Sperm PF00635.26 CDJ85292.1 - 5.7e-05 22.9 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Asp PF00026.23 CDJ85293.1 - 1.1e-48 166.3 0.0 1.7e-48 165.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ85293.1 - 5.9e-13 49.4 0.0 1.4e-12 48.3 0.0 1.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.12 CDJ85293.1 - 0.024 14.5 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 A1 Propeptide DUF1174 PF06671.11 CDJ85294.1 - 0.88 9.3 2.8 1.4 8.7 0.3 2.1 2 0 0 2 2 2 0 Repeat of unknown function (DUF1174) cwf21 PF08312.12 CDJ85295.1 - 6.2e-08 32.7 6.6 6.2e-08 32.7 6.6 2.7 3 0 0 3 3 3 1 cwf21 domain CTK3 PF12243.8 CDJ85295.1 - 0.00088 19.3 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTD_bind PF04818.13 CDJ85295.1 - 0.0014 19.4 4.0 0.0076 17.1 0.0 3.1 3 0 0 3 3 3 1 RNA polymerase II-binding domain. DNA_repr_REX1B PF14966.6 CDJ85295.1 - 0.16 12.6 5.1 1.3 9.8 1.0 3.4 3 1 1 4 4 4 0 DNA repair REX1-B Patched PF02460.18 CDJ85296.1 - 1.7e-65 221.6 19.7 4.7e-54 183.8 21.8 2.0 1 1 1 2 2 2 2 Patched family SHMT PF00464.19 CDJ85297.1 - 6.1e-182 604.6 0.0 1.2e-179 597.0 0.0 2.0 1 1 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 CDJ85297.1 - 0.0044 16.3 0.0 0.017 14.4 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase ETF_QO PF05187.13 CDJ85298.1 - 3.9e-49 165.1 0.3 8.1e-49 164.1 0.3 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 CDJ85298.1 - 7.5e-09 35.2 0.4 7.7e-05 21.9 1.1 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 CDJ85298.1 - 4.2e-08 33.2 0.3 0.00011 21.9 0.3 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDJ85298.1 - 9.7e-08 32.1 0.0 1e-06 28.8 0.0 2.6 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 CDJ85298.1 - 1.1e-05 24.5 1.3 0.0073 15.2 0.2 2.8 2 1 1 3 3 3 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 CDJ85298.1 - 1.1e-05 24.8 0.1 1.7e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDJ85298.1 - 1.6e-05 24.3 2.5 0.00011 21.5 0.1 2.5 3 0 0 3 3 3 1 Thi4 family NAD_binding_9 PF13454.6 CDJ85298.1 - 1.7e-05 24.8 0.0 4.4e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 CDJ85298.1 - 3.6e-05 24.2 0.4 0.035 14.7 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ85298.1 - 6.5e-05 21.8 0.0 9e-05 21.3 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 CDJ85298.1 - 0.00034 20.1 0.2 0.00064 19.2 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CDJ85298.1 - 0.0014 18.0 0.1 0.0031 16.8 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Fer4_7 PF12838.7 CDJ85298.1 - 0.0046 17.5 2.9 0.0054 17.3 1.3 1.9 2 0 0 2 2 1 1 4Fe-4S dicluster domain K_oxygenase PF13434.6 CDJ85298.1 - 0.0077 15.4 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 CDJ85298.1 - 0.0077 15.3 0.3 0.011 14.9 0.3 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 CDJ85298.1 - 0.013 14.8 0.1 0.021 14.1 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CDJ85298.1 - 0.21 10.6 0.1 0.33 10.0 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Avl9 PF09794.9 CDJ85299.1 - 4e-108 361.5 0.0 2.3e-107 359.0 0.0 1.9 1 1 0 1 1 1 1 Transport protein Avl9 Afi1 PF07792.12 CDJ85299.1 - 1.7e-08 35.0 0.0 4.4e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2347 PF09804.9 CDJ85299.1 - 1.3e-06 28.2 0.1 1.2e-05 25.0 0.0 2.3 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 CDJ85299.1 - 2e-05 24.5 0.0 0.066 13.2 0.0 3.0 3 0 0 3 3 3 2 Stabilization of polarity axis DENN PF02141.21 CDJ85299.1 - 0.00033 20.7 1.7 0.62 10.0 0.6 2.2 1 1 0 2 2 2 2 DENN (AEX-3) domain SET PF00856.28 CDJ85300.1 - 2.3e-14 54.1 0.0 9.8e-14 52.1 0.0 1.9 1 1 0 1 1 1 1 SET domain SMRP1 PF15181.6 CDJ85301.1 - 0.013 15.1 0.1 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 Spermatid-specific manchette-related protein 1 DUF5401 PF17380.2 CDJ85302.1 - 5.1e-24 84.4 147.4 5.1e-24 84.4 147.4 3.8 1 1 2 3 3 3 1 Family of unknown function (DUF5401) CBM_14 PF01607.24 CDJ85302.1 - 0.046 13.9 0.1 0.09 13.0 0.1 1.4 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain bZIP_2 PF07716.15 CDJ85303.1 - 4.7e-11 42.6 8.4 6.9e-11 42.1 8.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CDJ85303.1 - 7.9e-08 32.3 9.8 1.1e-07 31.8 9.8 1.2 1 0 0 1 1 1 1 bZIP transcription factor HALZ PF02183.18 CDJ85303.1 - 0.0017 18.5 0.3 0.0017 18.5 0.3 1.8 2 0 0 2 2 2 1 Homeobox associated leucine zipper RasGAP_C PF03836.15 CDJ85303.1 - 0.0021 18.2 1.2 0.0035 17.5 1.2 1.4 1 0 0 1 1 1 1 RasGAP C-terminus bZIP_Maf PF03131.17 CDJ85303.1 - 0.0031 18.0 5.4 0.0047 17.4 5.4 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor Prp19 PF08606.11 CDJ85303.1 - 0.02 14.9 0.4 0.032 14.2 0.4 1.3 1 0 0 1 1 1 0 Prp19/Pso4-like Laminin_II PF06009.12 CDJ85303.1 - 0.03 14.3 1.6 0.036 14.1 1.6 1.1 1 0 0 1 1 1 0 Laminin Domain II DivIC PF04977.15 CDJ85303.1 - 0.049 13.4 2.2 0.098 12.4 2.1 1.6 1 1 0 1 1 1 0 Septum formation initiator DUF4407 PF14362.6 CDJ85303.1 - 0.082 12.2 0.7 0.11 11.9 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM76 PF16046.5 CDJ85303.1 - 0.11 11.8 4.1 0.14 11.5 4.1 1.1 1 0 0 1 1 1 0 FAM76 protein bZIP_2 PF07716.15 CDJ85304.1 - 3.6e-12 46.2 15.2 6.3e-12 45.4 15.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CDJ85304.1 - 1.1e-09 38.2 14.0 1.7e-09 37.6 14.0 1.2 1 0 0 1 1 1 1 bZIP transcription factor TolA_bind_tri PF16331.5 CDJ85304.1 - 0.004 17.2 3.9 0.0061 16.6 3.9 1.3 1 0 0 1 1 1 1 TolA binding protein trimerisation SR-25 PF10500.9 CDJ85304.1 - 0.011 15.4 9.2 0.014 15.1 9.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Fungal_TACC PF12709.7 CDJ85304.1 - 0.027 14.9 3.5 0.037 14.5 2.9 1.5 1 1 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins WDCP PF15390.6 CDJ85304.1 - 0.028 12.8 2.4 0.031 12.7 2.4 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family bZIP_Maf PF03131.17 CDJ85304.1 - 0.029 14.9 12.4 0.039 14.5 12.0 1.4 1 1 0 1 1 1 0 bZIP Maf transcription factor DivIC PF04977.15 CDJ85304.1 - 0.065 13.0 6.7 0.041 13.7 4.8 1.6 1 1 0 1 1 1 0 Septum formation initiator RNA_pol_Rpc4 PF05132.14 CDJ85304.1 - 0.068 13.6 0.4 0.075 13.5 0.4 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Dsh_C PF12316.8 CDJ85304.1 - 0.58 10.5 11.1 0.84 10.0 11.1 1.3 1 1 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF4407 PF14362.6 CDJ85304.1 - 1.8 7.8 4.8 2.2 7.5 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 CDJ85304.1 - 7 5.3 5.2 7.7 5.2 5.2 1.1 1 0 0 1 1 1 0 Presenilin FANCI_HD2 PF14680.6 CDJ85306.1 - 7.6e-42 143.2 0.3 2e-41 141.8 0.3 1.8 1 0 0 1 1 1 1 FANCI helical domain 2 FANCI_S2 PF14676.6 CDJ85306.1 - 1.1e-11 45.3 0.7 5.3e-10 39.9 1.6 2.9 2 0 0 2 2 2 1 FANCI solenoid 2 SCIMP PF15050.6 CDJ85307.1 - 0.13 12.7 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 SCIMP protein CEND1 PF15677.5 CDJ85307.1 - 0.21 12.1 0.7 0.34 11.5 0.1 1.6 2 0 0 2 2 2 0 Cell cycle exit and neuronal differentiation protein 1 HemY_N PF07219.13 CDJ85307.1 - 0.21 11.8 0.2 0.68 10.2 0.1 1.7 2 0 0 2 2 2 0 HemY protein N-terminus Spermine_synth PF01564.17 CDJ85308.1 - 4e-10 39.4 0.3 6.4e-10 38.7 0.3 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 CDJ85308.1 - 6.3e-05 22.9 0.0 9.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ85308.1 - 0.0027 18.4 0.0 0.0053 17.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ85308.1 - 0.051 13.1 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain GDE_C PF06202.14 CDJ85309.1 - 0.00026 20.0 8.1 1.9 7.3 0.3 4.1 1 1 2 4 4 4 3 Amylo-alpha-1,6-glucosidase NiFeSe_Hases PF00374.19 CDJ85309.1 - 0.059 12.3 10.3 1.1 8.1 1.9 3.2 1 1 3 4 4 4 0 Nickel-dependent hydrogenase Nitr_red_assoc PF09655.10 CDJ85309.1 - 1.6 9.4 9.0 11 6.6 0.4 3.8 1 1 3 4 4 4 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) TTc_toxin_rep PF18807.1 CDJ85309.1 - 3.7 7.4 22.3 74 3.3 0.6 6.5 6 0 0 6 6 6 0 Tripartite Tc toxins repeat SWIRM-assoc_2 PF16496.5 CDJ85310.1 - 0.0092 14.9 0.6 0.01 14.8 0.6 1.1 1 0 0 1 1 1 1 SWIRM-associated domain at the N-terminal CDC45 PF02724.14 CDJ85310.1 - 0.42 8.8 4.2 0.45 8.7 4.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 CDJ85310.1 - 0.47 8.6 9.9 0.52 8.5 9.9 1.0 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 CDJ85310.1 - 1.5 9.1 10.5 1.9 8.8 10.5 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated NOA36 PF06524.12 CDJ85310.1 - 2.8 7.2 10.6 3.9 6.7 10.6 1.2 1 0 0 1 1 1 0 NOA36 protein eIF-3c_N PF05470.12 CDJ85310.1 - 5.5 5.2 7.2 6.6 4.9 7.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Pkinase PF00069.25 CDJ85311.1 - 2.5e-09 36.9 0.0 5.5e-09 35.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ85311.1 - 0.013 14.8 0.0 0.019 14.3 0.0 1.3 1 1 0 1 1 1 0 Protein tyrosine kinase gag-asp_proteas PF13975.6 CDJ85312.1 - 1.6e-05 25.3 0.2 0.00032 21.2 0.0 2.6 1 1 1 2 2 2 1 gag-polyprotein putative aspartyl protease zf-C2H2_10 PF16588.5 CDJ85312.1 - 0.0015 18.2 0.9 0.0031 17.2 0.9 1.5 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC PF00098.23 CDJ85312.1 - 0.0056 16.7 1.2 0.016 15.2 1.2 1.8 1 0 0 1 1 1 1 Zinc knuckle RVP PF00077.20 CDJ85312.1 - 0.037 14.3 0.0 0.21 11.9 0.0 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease CCM2_C PF16545.5 CDJ85312.1 - 0.059 13.9 0.4 0.3 11.6 0.1 2.2 2 0 0 2 2 2 0 Cerebral cavernous malformation protein, harmonin-homology PikAIV_N PF18605.1 CDJ85312.1 - 0.063 12.9 2.3 0.073 12.7 0.1 2.3 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain IES5 PF17335.2 CDJ85312.1 - 0.067 13.5 6.6 6.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Ino80 complex subunit 5 Asp_protease_2 PF13650.6 CDJ85312.1 - 0.072 13.7 0.1 0.55 10.9 0.0 2.4 1 1 1 2 2 2 0 Aspartyl protease DUF2452 PF10504.9 CDJ85312.1 - 0.27 10.7 5.5 0.18 11.3 2.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2452) TAF6_C PF07571.13 CDJ85313.1 - 0.14 12.5 0.1 35 4.8 0.0 2.7 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain AT_hook PF02178.19 CDJ85313.1 - 2.5 8.2 26.0 9.7 6.4 9.0 3.0 2 0 0 2 2 2 0 AT hook motif 7tm_1 PF00001.21 CDJ85314.1 - 2e-05 24.0 4.4 0.00034 20.0 0.5 2.4 1 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDJ85314.1 - 3.3e-05 23.3 7.8 0.029 13.7 4.0 2.5 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Serpentine_r_xa PF03383.15 CDJ85314.1 - 0.00063 19.7 0.9 0.0081 16.1 0.2 2.2 2 0 0 2 2 2 1 Caenorhabditis serpentine receptor-like protein, class xa 7TM_GPCR_Srx PF10328.9 CDJ85314.1 - 0.0019 17.9 2.1 0.0019 17.9 2.1 2.5 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 CDJ85314.1 - 0.84 9.0 7.6 0.26 10.6 0.2 2.6 3 0 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4572 PF15139.6 CDJ85315.1 - 0.0031 17.5 0.1 0.0035 17.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4572) HTH_26 PF13443.6 CDJ85315.1 - 0.038 14.4 0.1 0.068 13.6 0.1 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_IclR PF09339.10 CDJ85315.1 - 0.039 13.7 0.1 0.084 12.7 0.1 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain tRNA_int_end_N2 PF12928.7 CDJ85315.1 - 0.12 12.6 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term Lipase_GDSL_2 PF13472.6 CDJ85316.1 - 4.4e-13 50.0 0.1 1.2e-12 48.5 0.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CDJ85316.1 - 3.7e-12 46.7 0.1 5.5e-12 46.1 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase C6 PF01681.17 CDJ85317.1 - 9.6e-37 125.4 37.2 8.6e-11 42.2 1.4 12.2 13 1 1 14 14 14 6 C6 domain TSP_1 PF00090.19 CDJ85317.1 - 1.8e-05 24.8 28.7 0.00011 22.4 14.4 2.9 2 0 0 2 2 2 2 Thrombospondin type 1 domain HEPN PF05168.14 CDJ85318.1 - 0.11 12.7 0.4 0.17 12.0 0.2 1.5 1 1 0 1 1 1 0 HEPN domain Hormone_recep PF00104.30 CDJ85319.1 - 4.7e-28 98.2 0.5 6.8e-28 97.7 0.5 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 CDJ85319.1 - 1.3e-26 92.8 21.4 2.6e-26 91.9 21.4 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) zf-MYST PF17772.1 CDJ85321.1 - 2e-22 78.6 5.1 3e-22 78.0 5.1 1.3 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 CDJ85321.1 - 2.5e-17 62.5 0.1 4.3e-17 61.8 0.1 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MOZ_SAS PF01853.18 CDJ85321.1 - 8.8e-05 22.2 0.1 0.00021 21.0 0.0 1.7 2 0 0 2 2 2 1 MOZ/SAS family DUF4819 PF16090.5 CDJ85321.1 - 0.059 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4819) zf-met PF12874.7 CDJ85321.1 - 0.078 13.4 2.9 0.2 12.1 2.9 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CDJ85321.1 - 0.44 11.5 5.1 1.1 10.3 5.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger PurA PF04845.13 CDJ85322.1 - 3.4e-81 271.8 1.0 3.9e-81 271.6 1.0 1.0 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein DUF3276 PF11680.8 CDJ85322.1 - 1.9e-05 24.8 2.5 0.57 10.3 0.2 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF3276) HARE-HTH PF05066.13 CDJ85322.1 - 0.00029 21.2 0.1 10 6.6 0.0 3.4 3 0 0 3 3 3 2 HB1, ASXL, restriction endonuclease HTH domain DUF4478 PF14793.6 CDJ85322.1 - 0.019 14.9 0.1 2.5 8.0 0.0 2.3 2 0 0 2 2 2 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases KAR9 PF08580.10 CDJ85323.1 - 0.07 11.7 0.0 0.089 11.3 0.0 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 AAA_12 PF13087.6 CDJ85324.1 - 2.1e-33 115.6 0.0 3.6e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ85324.1 - 3.3e-10 40.2 0.0 5.6e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ85324.1 - 9.9e-09 35.2 0.2 0.0035 17.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CDJ85324.1 - 1.6e-08 35.0 0.3 4.4e-08 33.6 0.3 1.8 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 CDJ85324.1 - 2.5e-06 27.5 1.7 0.0038 17.1 1.7 2.6 1 1 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 CDJ85324.1 - 0.00012 21.9 0.0 0.15 11.8 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 CDJ85324.1 - 0.15 12.0 0.2 0.57 10.2 0.2 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit zf-C2H2_4 PF13894.6 CDJ85327.1 - 0.00019 22.0 12.8 0.024 15.5 1.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CDJ85327.1 - 0.00022 21.5 14.6 0.022 15.2 1.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 CDJ85327.1 - 0.00055 20.2 2.1 0.00057 20.1 2.1 1.1 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 CDJ85327.1 - 0.0016 18.8 5.2 0.0016 18.8 5.2 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 CDJ85327.1 - 0.042 14.2 6.2 0.27 11.7 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type EB PF01683.18 CDJ85331.1 - 2.8e-07 30.7 5.8 2.8e-07 30.7 5.8 2.3 1 1 1 2 2 2 2 EB module Lustrin_cystein PF14625.6 CDJ85332.1 - 8.9e-27 93.2 79.4 9e-10 38.8 8.5 6.5 6 1 0 6 6 6 4 Lustrin, cysteine-rich repeated domain EB PF01683.18 CDJ85332.1 - 1.3e-13 51.0 21.5 1.3e-11 44.6 11.6 6.1 4 2 1 5 5 5 2 EB module Inhibitor_I36 PF03995.13 CDJ85332.1 - 1.6 8.7 27.3 0.97 9.4 2.6 4.9 4 1 0 4 4 4 0 Peptidase inhibitor family I36 Lustrin_cystein PF14625.6 CDJ85333.1 - 2.7e-10 40.5 9.1 2.7e-10 40.5 9.1 1.9 2 0 0 2 2 2 1 Lustrin, cysteine-rich repeated domain RVT_1 PF00078.27 CDJ85334.1 - 7e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Succ_DH_flav_C PF02910.20 CDJ85334.1 - 0.00075 19.5 1.2 1.3 9.0 0.1 2.4 2 0 0 2 2 2 2 Fumarate reductase flavoprotein C-term DUF2315 PF10231.9 CDJ85334.1 - 0.026 14.6 1.7 2.5 8.2 0.1 2.4 2 0 0 2 2 2 0 Apoptogenic protein 1 Pericardin_rpt PF07054.11 CDJ85334.1 - 0.74 10.0 2.4 6 7.1 0.4 2.3 2 0 0 2 2 2 0 Pericardin like repeat Peptidase_M1_N PF17900.1 CDJ85335.1 - 1.1e-39 136.5 0.0 1.6e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Pkinase PF00069.25 CDJ85336.1 - 9.2e-60 202.2 0.0 1.1e-59 202.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ85336.1 - 5.1e-37 127.6 0.0 6.8e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ85336.1 - 2.7e-11 43.3 0.0 4.1e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CDJ85336.1 - 0.013 15.4 0.0 0.042 13.8 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDJ85336.1 - 0.048 12.6 0.4 0.066 12.1 0.4 1.1 1 0 0 1 1 1 0 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 CDJ85336.1 - 0.057 12.9 0.1 0.09 12.3 0.1 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 CDJ85336.1 - 0.18 11.4 3.6 0.2 11.2 0.2 2.0 1 1 0 2 2 2 0 RIO1 family Ank_2 PF12796.7 CDJ85337.1 - 9.6e-40 135.1 0.8 1.4e-17 64.1 0.1 5.4 4 2 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ85337.1 - 2.7e-33 113.9 2.3 1.3e-08 35.2 0.0 8.0 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 CDJ85337.1 - 3e-30 103.3 8.8 0.00027 21.3 0.0 10.0 10 0 0 10 10 10 6 Ankyrin repeat Ank_3 PF13606.6 CDJ85337.1 - 1.5e-29 98.7 11.9 0.00014 22.0 0.0 9.7 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 CDJ85337.1 - 4.7e-28 96.9 6.5 8.4e-05 22.8 0.1 7.4 4 1 3 7 7 7 6 Ankyrin repeats (many copies) PL48 PF15903.5 CDJ85339.1 - 1.7e-32 112.8 5.4 2.9e-32 112.0 1.6 2.7 2 1 0 2 2 2 1 Filopodia upregulated, FAM65 HEAT_2 PF13646.6 CDJ85339.1 - 0.017 15.5 0.2 0.088 13.2 0.1 2.3 2 0 0 2 2 2 0 HEAT repeats Aminopep PF10023.9 CDJ85339.1 - 0.021 14.2 0.9 0.087 12.2 0.2 2.1 2 0 0 2 2 2 0 Putative aminopeptidase HEAT_EZ PF13513.6 CDJ85339.1 - 0.17 12.4 0.4 12 6.6 0.1 3.0 2 0 0 2 2 2 0 HEAT-like repeat GSHPx PF00255.19 CDJ85341.1 - 5e-39 132.2 0.3 6.8e-39 131.8 0.3 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CDJ85341.1 - 3.5e-10 39.9 0.1 5.6e-10 39.2 0.1 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDJ85341.1 - 6e-07 29.3 0.1 1.3e-05 25.0 0.1 2.3 1 1 0 1 1 1 1 Redoxin Anophelin PF10731.9 CDJ85342.1 - 0.65 9.9 4.7 1.1 9.2 4.7 1.4 1 1 0 1 1 1 0 Thrombin inhibitor from mosquito Pkinase PF00069.25 CDJ85343.1 - 5.6e-61 206.2 0.0 7.1e-61 205.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ85343.1 - 5.7e-40 137.2 0.0 7.2e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ85343.1 - 2.5e-07 30.3 0.0 4.3e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CDJ85343.1 - 2e-06 26.9 0.0 2.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CDJ85343.1 - 7.3e-05 21.9 0.2 0.00011 21.3 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CDJ85343.1 - 0.0051 16.2 0.2 0.0084 15.5 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 CDJ85343.1 - 0.0079 15.9 0.1 2.3 7.8 0.1 2.4 2 0 0 2 2 2 2 Protein-kinase domain of FAM69 APH PF01636.23 CDJ85343.1 - 0.049 13.5 0.0 0.16 11.9 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family DDE_3 PF13358.6 CDJ85344.1 - 4.2e-05 23.3 0.1 5.3e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Serpin PF00079.20 CDJ85345.1 - 1.1e-88 298.0 1.7 1.3e-88 297.9 1.7 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) CBM77 PF18283.1 CDJ85345.1 - 0.29 11.5 2.7 0.34 11.3 0.3 2.3 3 0 0 3 3 3 0 Carbohydrate binding module 77 Serpin PF00079.20 CDJ85347.1 - 4.9e-90 302.5 5.4 5.8e-90 302.3 5.4 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 CDJ85348.1 - 2.8e-91 306.6 6.8 3.2e-91 306.4 6.8 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 CDJ85349.1 - 8.5e-63 212.9 0.1 1e-62 212.6 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Phage_integrase PF00589.22 CDJ85350.1 - 0.0099 15.7 0.0 0.22 11.3 0.0 2.1 2 0 0 2 2 2 2 Phage integrase family Aminotran_3 PF00202.21 CDJ85351.1 - 2.1e-107 359.3 0.0 2.6e-107 359.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Y_phosphatase PF00102.27 CDJ85352.1 - 2.3e-75 253.2 4.4 5.7e-71 238.8 0.2 3.0 3 0 0 3 3 3 2 Protein-tyrosine phosphatase fn3 PF00041.21 CDJ85352.1 - 1.9e-29 101.9 2.0 1.3e-13 51.0 0.5 3.5 3 0 0 3 3 3 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CDJ85352.1 - 5.3e-10 39.7 1.7 0.00067 20.2 0.4 3.6 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain DSPc PF00782.20 CDJ85352.1 - 0.00058 19.7 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PhoD_N PF16655.5 CDJ85352.1 - 0.0044 17.5 0.1 0.19 12.3 0.1 2.6 2 0 0 2 2 2 1 PhoD-like phosphatase, N-terminal domain I-set PF07679.16 CDJ85352.1 - 0.0091 16.0 0.0 1.5 8.9 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ85352.1 - 0.032 14.8 0.1 2.8 8.6 0.0 3.2 3 0 0 3 3 3 0 Immunoglobulin domain Ig_6 PF18452.1 CDJ85352.1 - 0.046 13.3 0.0 0.51 9.9 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain ig PF00047.25 CDJ85352.1 - 0.065 13.4 0.0 15 5.8 0.1 3.0 2 0 0 2 2 2 0 Immunoglobulin domain TPT PF03151.16 CDJ85353.1 - 5e-15 55.6 18.6 6e-15 55.4 18.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family CAF1 PF04857.20 CDJ85353.1 - 0.18 11.0 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease Roc PF08477.13 CDJ85354.1 - 2.3e-17 63.3 0.0 6.7e-17 61.8 0.0 1.8 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDJ85354.1 - 1.1e-12 47.8 0.0 3.4e-12 46.2 0.0 1.8 1 1 0 1 1 1 1 Ras family DnaJ PF00226.31 CDJ85354.1 - 1.6e-12 47.3 0.0 2.8e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain MMR_HSR1 PF01926.23 CDJ85354.1 - 4.5e-08 33.2 0.0 7.4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.13 CDJ85354.1 - 1.1e-06 28.0 0.2 1.6e-06 27.5 0.2 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 CDJ85354.1 - 0.00012 22.0 0.0 0.00019 21.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 CDJ85354.1 - 0.00028 21.3 0.0 0.00051 20.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain zf-CSL PF05207.13 CDJ85354.1 - 0.00034 20.3 0.0 0.00061 19.5 0.0 1.4 1 0 0 1 1 1 1 CSL zinc finger Arf PF00025.21 CDJ85354.1 - 0.00042 19.8 0.0 0.00071 19.1 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Septin PF00735.18 CDJ85354.1 - 0.0011 18.4 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Septin ABC_tran PF00005.27 CDJ85354.1 - 0.0013 19.2 0.0 0.0022 18.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Dynamin_N PF00350.23 CDJ85354.1 - 0.005 16.9 0.0 0.0077 16.3 0.0 1.3 1 0 0 1 1 1 1 Dynamin family AAA_24 PF13479.6 CDJ85354.1 - 0.0085 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CDJ85354.1 - 0.025 15.0 0.0 0.16 12.4 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Gtr1_RagA PF04670.12 CDJ85354.1 - 0.039 13.3 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA PF00004.29 CDJ85354.1 - 0.059 13.8 0.0 0.094 13.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ85354.1 - 0.065 13.5 0.1 0.23 11.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 CDJ85354.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AIG1 PF04548.16 CDJ85354.1 - 0.094 12.0 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 AIG1 family AAA_29 PF13555.6 CDJ85354.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 CDJ85354.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SMC_N PF02463.19 CDJ85354.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Cu_amine_oxidN2 PF02727.16 CDJ85354.1 - 0.16 12.2 0.0 0.37 11.1 0.0 1.6 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain AAA_23 PF13476.6 CDJ85354.1 - 0.18 12.3 0.0 0.45 11.0 0.0 1.6 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.26 CDJ85354.1 - 0.19 11.4 0.0 0.28 10.9 0.0 1.4 1 1 0 1 1 1 0 Sigma-54 interaction domain Tmemb_185A PF10269.9 CDJ85355.1 - 2.9e-47 161.5 20.1 4.3e-47 160.9 20.1 1.2 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein RVT_1 PF00078.27 CDJ85356.1 - 7.2e-14 51.8 0.0 1.1e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) bZIP_2 PF07716.15 CDJ85357.1 - 1.1e-06 28.6 17.3 1.9e-06 27.8 17.3 1.4 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CDJ85357.1 - 0.0002 21.8 7.5 0.00028 21.3 7.5 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 CDJ85357.1 - 0.001 19.1 12.3 0.0014 18.7 12.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor Cnn_1N PF07989.11 CDJ85357.1 - 0.022 14.9 2.8 0.032 14.4 2.8 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Glyco_hydro_15 PF00723.21 CDJ85358.1 - 3.7e-126 421.5 0.0 5.1e-126 421.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 SL4P PF17618.2 CDJ85359.1 - 5e-10 39.3 0.0 6.7e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized Strongylid L4 protein Tmpp129 PF10272.9 CDJ85359.1 - 0.096 12.0 0.0 0.11 11.8 0.0 1.0 1 0 0 1 1 1 0 Putative transmembrane protein precursor SL4P PF17618.2 CDJ85361.1 - 3.9e-25 87.7 0.2 4.9e-25 87.4 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized Strongylid L4 protein Ribosomal_L21e PF01157.18 CDJ85361.1 - 0.061 13.2 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L21e Lebercilin PF15619.6 CDJ85365.1 - 0.0019 17.9 11.7 0.14 11.8 1.3 2.3 2 0 0 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease SKA1 PF07160.12 CDJ85365.1 - 0.011 15.6 2.3 1 9.2 2.5 2.4 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 MutS_IV PF05190.18 CDJ85365.1 - 0.045 14.1 1.2 0.35 11.2 0.0 2.3 2 0 0 2 2 2 0 MutS family domain IV SOGA PF11365.8 CDJ85365.1 - 0.1 13.7 5.8 0.85 10.8 0.1 3.1 2 1 1 3 3 3 0 Protein SOGA ATG16 PF08614.11 CDJ85365.1 - 0.21 11.8 8.5 1.5 9.0 0.3 2.2 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF3287 PF11690.8 CDJ85365.1 - 0.23 11.2 3.4 0.099 12.4 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) FliD_N PF02465.18 CDJ85365.1 - 0.26 12.0 1.3 0.76 10.5 0.8 1.8 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DHR10 PF18595.1 CDJ85365.1 - 0.27 11.3 7.2 0.8 9.8 1.4 2.4 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain KxDL PF10241.9 CDJ85365.1 - 0.38 11.1 5.9 8.6 6.7 0.1 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein PI3K_P85_iSH2 PF16454.5 CDJ85365.1 - 0.39 10.3 12.4 1.3 8.6 1.8 3.0 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Cnn_1N PF07989.11 CDJ85365.1 - 0.51 10.5 11.9 2.2 8.5 0.4 3.2 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 CENP-F_leu_zip PF10473.9 CDJ85365.1 - 0.51 10.3 10.0 5.5 7.0 4.5 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.6 CDJ85365.1 - 2 8.4 12.5 0.68 9.9 0.4 2.4 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Csm1_N PF18504.1 CDJ85365.1 - 3.2 8.2 7.4 2.4 8.5 2.2 2.6 2 1 0 2 2 2 0 Csm1 N-terminal domain JIP_LZII PF16471.5 CDJ85365.1 - 7.9 6.7 8.8 2.3 8.4 0.7 2.6 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II Uso1_p115_C PF04871.13 CDJ85366.1 - 0.013 15.9 4.0 0.018 15.4 4.0 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Aminotran_1_2 PF00155.21 CDJ85366.1 - 0.04 13.1 0.5 0.054 12.6 0.5 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II TSC22 PF01166.18 CDJ85366.1 - 0.047 14.0 0.8 0.047 14.0 0.8 2.3 1 1 2 3 3 3 0 TSC-22/dip/bun family DUF600 PF04634.12 CDJ85366.1 - 0.074 13.1 0.1 0.1 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF600 Jnk-SapK_ap_N PF09744.9 CDJ85366.1 - 0.11 12.7 14.1 0.76 10.0 1.9 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 SEO_N PF14576.6 CDJ85366.1 - 0.21 10.7 3.2 0.26 10.4 2.6 1.3 1 1 0 1 1 1 0 Sieve element occlusion N-terminus Syntaxin-6_N PF09177.11 CDJ85366.1 - 0.24 12.0 4.6 0.39 11.3 3.7 1.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Hpt PF01627.23 CDJ85366.1 - 0.41 10.9 6.9 3.1 8.1 6.9 2.2 1 1 0 1 1 1 0 Hpt domain GIT_CC PF16559.5 CDJ85366.1 - 0.49 10.3 15.0 0.076 12.9 8.8 2.7 2 1 2 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 CDJ85366.1 - 1.1 10.0 5.9 3 8.5 5.9 1.9 1 1 0 1 1 1 0 Initiation control protein YabA bZIP_1 PF00170.21 CDJ85366.1 - 1.1 9.4 9.1 0.18 11.9 4.3 2.0 2 0 0 2 2 2 0 bZIP transcription factor HR1 PF02185.16 CDJ85366.1 - 3 8.0 13.0 12 6.1 13.0 2.0 1 1 0 1 1 1 0 Hr1 repeat TolA_bind_tri PF16331.5 CDJ85366.1 - 3.9 7.6 15.0 0.53 10.4 7.0 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation SH2 PF00017.24 CDJ85367.1 - 1.8e-13 50.4 0.0 2.4e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 SH2 domain Cadherin PF00028.17 CDJ85369.1 - 1.5e-124 406.8 10.6 2.8e-15 56.5 0.0 18.5 19 1 1 20 20 20 15 Cadherin domain Cadherin_3 PF16184.5 CDJ85369.1 - 8.8e-07 28.9 4.2 0.12 12.4 0.1 7.0 6 0 0 6 6 6 1 Cadherin-like DUF5527 PF17665.1 CDJ85369.1 - 0.31 10.6 1.9 0.72 9.4 1.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Nop14 PF04147.12 CDJ85369.1 - 0.49 8.5 2.6 0.8 7.8 2.6 1.2 1 0 0 1 1 1 0 Nop14-like family He_PIG PF05345.12 CDJ85369.1 - 1.2 9.4 21.3 1 9.6 0.0 9.2 11 0 0 11 11 11 0 Putative Ig domain TPR_16 PF13432.6 CDJ85371.1 - 1.5e-06 28.8 0.1 0.0019 18.8 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ85371.1 - 0.15 11.8 0.0 0.54 10.0 0.0 1.9 2 0 0 2 2 2 0 TPR repeat Asp_Arg_Hydrox PF05118.15 CDJ85372.1 - 2.6e-43 147.6 0.0 3.5e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase TPR_8 PF13181.6 CDJ85372.1 - 0.00013 21.9 0.3 0.073 13.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ85372.1 - 0.001 19.0 0.7 0.63 10.3 0.1 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ85372.1 - 0.0019 18.5 0.9 0.053 13.9 0.0 3.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ85372.1 - 0.056 13.3 0.9 17 5.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CDJ85372.1 - 0.069 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_19 PF14559.6 CDJ85372.1 - 0.14 12.7 0.0 0.43 11.1 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat PDZ PF00595.24 CDJ85373.1 - 3.8e-61 203.4 0.7 1.4e-15 57.4 0.0 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 CDJ85373.1 - 4e-42 141.9 3.8 8.6e-10 38.3 0.1 4.7 4 0 0 4 4 4 4 PDZ domain LRR_8 PF13855.6 CDJ85373.1 - 1.7e-39 133.4 48.5 1.1e-08 34.7 2.6 7.0 3 2 5 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 CDJ85373.1 - 4.5e-30 103.2 57.9 2.8e-05 24.4 0.2 9.4 8 1 1 9 9 9 8 Leucine Rich repeats (2 copies) PDZ_2 PF13180.6 CDJ85373.1 - 8.1e-28 96.6 0.1 2.2e-07 31.1 0.0 4.9 4 0 0 4 4 4 4 PDZ domain LRR_1 PF00560.33 CDJ85373.1 - 0.00023 21.3 43.9 4.4 8.2 0.1 12.5 14 1 0 14 14 14 2 Leucine Rich Repeat LRR_5 PF13306.6 CDJ85373.1 - 0.034 14.1 1.2 0.39 10.7 0.5 2.7 2 1 1 3 3 3 0 BspA type Leucine rich repeat region (6 copies) Saw1 PF11561.8 CDJ85373.1 - 0.19 11.2 2.9 0.19 11.3 0.3 2.0 2 0 0 2 2 2 0 Single strand annealing-weakened 1 Lung_7-TM_R PF06814.13 CDJ85374.1 - 9.2e-58 195.8 13.7 1.2e-57 195.4 13.7 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 CDJ85374.1 - 0.0033 16.9 17.8 0.0047 16.4 17.8 1.3 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Tmemb_cc2 PF10267.9 CDJ85375.1 - 9.3e-77 258.8 1.3 1.3e-76 258.4 1.3 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein PP1_bind PF15276.6 CDJ85375.1 - 0.0035 17.6 0.2 0.0098 16.2 0.2 1.7 1 0 0 1 1 1 1 Protein phosphatase 1 binding Muted PF14942.6 CDJ85375.1 - 0.012 15.9 2.9 0.012 15.9 2.9 2.6 2 1 1 3 3 3 0 Organelle biogenesis, Muted-like protein Exonuc_VII_L PF02601.15 CDJ85375.1 - 0.043 13.4 6.4 0.81 9.2 0.5 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Baculo_PEP_C PF04513.12 CDJ85375.1 - 0.096 12.7 2.5 5.8 7.0 0.5 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cdh1_DBD_1 PF18196.1 CDJ85375.1 - 0.14 12.4 3.8 0.48 10.7 0.2 2.5 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Spc7 PF08317.11 CDJ85375.1 - 0.19 10.5 13.8 0.043 12.7 1.6 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein SKA2 PF16740.5 CDJ85375.1 - 0.24 11.2 6.7 0.17 11.7 1.9 2.6 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Fib_alpha PF08702.10 CDJ85375.1 - 0.38 10.9 8.4 3.7 7.7 0.1 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Phage_Mu_Gam PF07352.12 CDJ85375.1 - 0.84 9.5 6.2 1.5 8.7 0.1 3.0 2 1 0 3 3 3 0 Bacteriophage Mu Gam like protein DUF2730 PF10805.8 CDJ85375.1 - 0.86 9.7 4.3 3.3 7.9 0.1 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF2730) COG2 PF06148.11 CDJ85375.1 - 0.88 9.7 7.2 8.7 6.4 0.1 3.4 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 FapA PF03961.13 CDJ85375.1 - 1.2 7.7 11.1 1.9 7.0 1.3 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A TMPIT PF07851.13 CDJ85375.1 - 1.7 7.8 8.5 2 7.6 1.4 2.3 2 0 0 2 2 2 0 TMPIT-like protein WDCP PF15390.6 CDJ85375.1 - 2 6.7 5.2 0.32 9.3 1.1 1.6 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family DUF1664 PF07889.12 CDJ85375.1 - 2.4 8.2 8.0 3.3 7.8 1.6 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Uso1_p115_C PF04871.13 CDJ85375.1 - 3.4 8.1 14.9 4.3 7.7 5.3 2.5 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Ground-like PF04155.18 CDJ85377.1 - 2.1e-11 44.3 0.1 2.6e-11 44.0 0.1 1.1 1 0 0 1 1 1 1 Ground-like domain DUF5352 PF17303.2 CDJ85377.1 - 0.0027 17.6 0.0 0.0033 17.3 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5352) zf-C4 PF00105.18 CDJ85378.1 - 6.8e-24 84.1 11.1 1.3e-23 83.2 11.1 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ85378.1 - 4.2e-18 65.7 0.0 6.1e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Peptidase_A22B PF04258.13 CDJ85379.1 - 1.2e-96 323.6 1.8 1.7e-96 323.1 1.8 1.2 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 CDJ85379.1 - 1e-06 28.4 3.4 2e-06 27.5 3.4 1.5 1 0 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease Clc-like PF07062.12 CDJ85380.1 - 1.8e-06 27.6 8.9 1.8e-06 27.6 8.9 1.5 1 1 0 1 1 1 1 Clc-like Claudin_2 PF13903.6 CDJ85380.1 - 4.8e-05 23.2 7.4 0.00011 22.0 7.4 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 CDJ85380.1 - 6.6e-05 22.8 4.9 6.6e-05 22.8 4.9 1.7 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family Phosphodiest PF01663.22 CDJ85382.1 - 7.9e-25 88.2 1.4 1e-24 87.9 1.4 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Shisa PF13908.6 CDJ85382.1 - 0.17 12.1 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Class_IIIsignal PF04021.12 CDJ85382.1 - 2.6 8.1 8.2 6.7 6.8 8.2 1.6 1 0 0 1 1 1 0 Class III signal peptide Adaptin_N PF01602.20 CDJ85383.1 - 1.1e-151 506.0 7.8 1.4e-151 505.7 7.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 CDJ85383.1 - 3.2e-41 140.0 0.0 9.3e-41 138.6 0.0 1.9 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 CDJ85383.1 - 5.9e-18 65.2 0.2 1.4e-17 64.0 0.2 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 CDJ85383.1 - 3.3e-09 37.0 0.4 2.4e-07 31.0 0.0 2.9 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDJ85383.1 - 4.7e-05 23.7 0.9 0.11 12.8 0.1 4.4 3 2 1 4 4 4 1 HEAT repeats B2-adapt-app_C PF09066.10 CDJ85383.1 - 0.0015 18.6 0.2 0.0065 16.5 0.0 2.2 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain VPS28 PF03997.12 CDJ85383.1 - 0.032 13.9 0.0 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 VPS28 protein DRIM PF07539.12 CDJ85383.1 - 0.058 11.7 6.1 0.87 7.8 3.8 2.5 2 1 0 2 2 2 0 Down-regulated in metastasis AP4E_app_platf PF14807.6 CDJ85383.1 - 0.1 13.0 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform FixQ PF05545.11 CDJ85385.1 - 0.015 15.3 0.2 0.015 15.3 0.2 1.9 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ MANEC PF07502.14 CDJ85385.1 - 0.063 13.6 0.3 0.14 12.4 0.3 1.5 1 0 0 1 1 1 0 MANEC domain Laminin_EGF PF00053.24 CDJ85385.1 - 5.1 7.3 7.3 2.4 8.4 4.6 1.9 2 0 0 2 2 2 0 Laminin EGF domain cEGF PF12662.7 CDJ85385.1 - 6.2 6.9 6.5 16 5.5 1.5 2.8 2 0 0 2 2 2 0 Complement Clr-like EGF-like EF-hand_1 PF00036.32 CDJ85386.1 - 1.8e-10 39.6 0.3 1.4e-06 27.4 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CDJ85386.1 - 1.7e-09 36.9 0.1 1e-05 25.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CDJ85386.1 - 7.9e-09 35.9 1.0 2.2e-08 34.4 1.0 1.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 CDJ85386.1 - 5.3e-05 22.5 1.4 0.00043 19.6 0.3 2.5 2 1 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 CDJ85386.1 - 0.0002 21.1 1.3 0.0008 19.2 0.3 2.0 1 1 1 2 2 2 1 EF-hand domain pair DUF3173 PF11372.8 CDJ85386.1 - 0.11 12.3 0.0 0.67 9.9 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3173) EF-hand_7 PF13499.6 CDJ85387.1 - 5.7e-08 33.1 1.2 0.00051 20.4 0.1 1.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ85387.1 - 3.7e-06 26.7 3.5 0.0041 16.9 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CDJ85387.1 - 4.4e-06 25.9 1.0 1.1e-05 24.7 0.3 2.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CDJ85387.1 - 3.9e-05 23.3 0.7 8.2e-05 22.2 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CDJ85387.1 - 0.0079 15.6 0.2 0.016 14.7 0.2 1.5 1 0 0 1 1 1 1 EF hand DUF3911 PF13050.6 CDJ85387.1 - 0.11 12.6 0.8 0.37 10.9 0.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3911) Tetraspanin PF00335.20 CDJ85389.1 - 1.1e-09 38.4 2.3 1.3e-09 38.1 2.3 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2570 PF10828.8 CDJ85389.1 - 0.17 11.7 0.9 0.18 11.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) RVT_1 PF00078.27 CDJ85390.1 - 1.8e-31 109.4 0.0 3.5e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CDJ85392.1 - 1.2e-35 123.0 0.0 2.6e-35 122.0 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDJ85393.1 - 0.00023 21.0 0.0 0.00065 19.5 0.0 1.8 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ85393.1 - 0.0028 17.2 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DNA_pol_phi PF04931.13 CDJ85395.1 - 4.6 5.2 7.5 7.1 4.6 7.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi Trypan_PARP PF05887.11 CDJ85396.1 - 1.1e-05 25.4 120.6 0.024 14.6 11.7 5.9 1 1 2 3 3 3 2 Procyclic acidic repetitive protein (PARP) 7tm_1 PF00001.21 CDJ85397.1 - 4.9e-08 32.6 6.4 7.1e-08 32.1 6.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ85397.1 - 0.064 12.6 4.2 0.087 12.2 4.2 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_2 PF00002.24 CDJ85398.1 - 2.1e-58 197.5 11.2 2.8e-58 197.1 11.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 CDJ85398.1 - 6.1e-10 39.3 4.3 1.1e-09 38.4 4.3 1.5 1 0 0 1 1 1 1 Hormone receptor domain SDF PF00375.18 CDJ85400.1 - 5.2e-106 355.0 25.5 5.9e-106 354.8 25.5 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Sld5 PF05916.11 CDJ85401.1 - 4.7e-06 27.0 0.3 0.00022 21.6 0.2 2.3 2 1 0 2 2 2 1 GINS complex protein Atx10homo_assoc PF09759.9 CDJ85401.1 - 0.1 12.6 0.8 0.2 11.7 0.8 1.4 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain RNase_Zc3h12a PF11977.8 CDJ85402.1 - 8e-21 74.4 0.0 3.6e-20 72.3 0.0 1.9 2 0 0 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain DUF5360 PF17314.2 CDJ85402.1 - 0.065 13.3 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5360) Acetyltransf_1 PF00583.25 CDJ85404.1 - 3.4e-05 24.0 0.0 5.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDJ85404.1 - 4.9e-05 23.3 0.0 6.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDJ85404.1 - 0.00011 22.6 0.0 0.00014 22.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CDJ85404.1 - 0.053 13.7 0.0 0.081 13.1 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 CDJ85404.1 - 0.17 11.9 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein PanZ PF12568.8 CDJ85404.1 - 0.19 11.4 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Y_phosphatase PF00102.27 CDJ85405.1 - 9.5e-71 238.1 0.2 1.4e-70 237.6 0.2 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ85405.1 - 2.6e-07 30.5 0.1 9e-07 28.8 0.1 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Phi-29_GP16_7 PF06720.11 CDJ85405.1 - 0.018 14.9 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 Eryth_link_C PF16915.5 CDJ85405.1 - 0.092 12.8 0.2 0.62 10.1 0.1 2.2 2 0 0 2 2 2 0 Annelid erythrocruorin linker subunit C-terminus Y_phosphatase PF00102.27 CDJ85406.1 - 1.4e-66 224.4 0.1 1.4e-66 224.4 0.1 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ85406.1 - 0.00053 19.8 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Pmp3 PF01679.17 CDJ85409.1 - 1.9e-11 44.0 9.2 2.5e-11 43.6 9.2 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TFIID-18kDa PF02269.16 CDJ85410.1 - 1.3e-35 121.2 0.3 1.8e-35 120.9 0.3 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 CDJ85410.1 - 0.055 13.5 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated DUF4947 PF16305.5 CDJ85410.1 - 0.14 12.2 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4947) Astacin PF01400.24 CDJ85411.1 - 1.4e-55 187.9 0.1 1.4e-32 112.9 0.0 3.2 2 1 1 3 3 3 3 Astacin (Peptidase family M12A) ABC_tran_CTD PF16326.5 CDJ85411.1 - 0.021 15.1 1.9 2.8 8.2 0.1 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF4479 PF14794.6 CDJ85411.1 - 0.034 14.0 0.4 3.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) DUF3673 PF12425.8 CDJ85411.1 - 0.1 12.5 0.3 22 5.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3673) DUF5371 PF17341.2 CDJ85411.1 - 0.19 12.0 2.8 8.2 6.7 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5371) Astacin PF01400.24 CDJ85412.1 - 6e-143 472.9 19.0 2e-55 187.4 1.4 5.1 4 1 1 5 5 5 5 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 CDJ85412.1 - 5e-09 36.2 0.1 0.24 11.3 0.0 3.9 3 2 0 3 3 3 3 Matrixin RBM39linker PF15519.6 CDJ85412.1 - 5.3e-05 24.2 0.2 4.9 8.3 0.0 3.5 3 0 0 3 3 3 2 linker between RRM2 and RRM3 domains in RBM39 protein Reprolysin_4 PF13583.6 CDJ85412.1 - 0.00044 20.0 3.4 2.2 7.8 0.1 3.4 3 0 0 3 3 3 3 Metallo-peptidase family M12B Reprolysin-like DUF3267 PF11667.8 CDJ85412.1 - 0.0058 16.9 1.8 27 5.1 0.0 3.7 3 0 0 3 3 3 0 Putative zincin peptidase DUF3675 PF12428.8 CDJ85412.1 - 0.036 14.6 1.8 8.1 7.0 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3675) HTH_9 PF08221.11 CDJ85412.1 - 0.07 13.2 0.2 3.5 7.8 0.0 3.1 3 0 0 3 3 3 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Ntox44 PF15607.6 CDJ85412.1 - 0.92 9.8 3.3 34 4.8 0.1 3.1 3 0 0 3 3 3 0 Bacterial toxin 44 Astacin PF01400.24 CDJ85414.1 - 1.7e-18 67.0 8.0 1.3e-13 51.0 2.2 2.7 2 1 1 3 3 3 2 Astacin (Peptidase family M12A) Glyco_transf_92 PF01697.27 CDJ85415.1 - 6.6e-59 199.7 0.8 8.9e-59 199.3 0.8 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 CDJ85415.1 - 0.00066 20.1 0.3 0.0015 19.0 0.3 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Peptidase_M13_N PF05649.13 CDJ85416.1 - 2.7e-45 155.7 2.0 3.4e-45 155.4 2.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Trypan_PARP PF05887.11 CDJ85416.1 - 0.00015 21.8 34.8 0.00015 21.8 34.8 2.2 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Dicty_REP PF05086.12 CDJ85416.1 - 0.014 13.4 7.1 0.017 13.1 4.1 2.0 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein PfUIS3 PF11567.8 CDJ85416.1 - 0.038 14.4 0.2 0.12 12.8 0.2 1.8 1 0 0 1 1 1 0 Plasmodium falciparum UIS3 membrane protein GST_N_4 PF17172.4 CDJ85416.1 - 0.17 12.7 0.4 22 5.9 0.1 3.0 3 0 0 3 3 3 0 Glutathione S-transferase N-terminal domain SCVP PF17619.2 CDJ85417.1 - 8.4e-13 49.0 0.8 1e-12 48.7 0.8 1.1 1 0 0 1 1 1 1 Secreted clade V proteins MatP PF06303.12 CDJ85417.1 - 0.14 12.7 0.0 0.25 11.9 0.0 1.4 1 1 0 1 1 1 0 MatP N-terminal domain Synaptobrevin PF00957.21 CDJ85420.1 - 0.045 13.6 0.3 0.053 13.3 0.3 1.1 1 0 0 1 1 1 0 Synaptobrevin CUB PF00431.20 CDJ85421.1 - 1.5e-38 131.5 1.1 1.2e-18 67.4 0.3 2.1 2 0 0 2 2 2 2 CUB domain CUB_2 PF02408.20 CDJ85421.1 - 0.045 13.5 3.6 0.72 9.6 1.2 2.3 2 0 0 2 2 2 0 CUB-like domain Sdh5 PF03937.16 CDJ85422.1 - 3.2e-21 75.1 0.1 4.8e-21 74.5 0.1 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase DAO PF01266.24 CDJ85423.1 - 3e-61 208.0 0.0 3.6e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.15 CDJ85423.1 - 0.0014 17.2 0.0 0.38 9.3 0.0 2.3 2 1 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Trp_halogenase PF04820.14 CDJ85423.1 - 0.064 12.1 0.0 0.091 11.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_8 PF13450.6 CDJ85423.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain EB1 PF03271.17 CDJ85424.1 - 3.2e-11 43.3 0.4 6.4e-11 42.3 0.4 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 CDJ85424.1 - 1.6e-10 41.2 1.9 1.6e-10 41.2 1.9 1.9 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CDJ85424.1 - 0.032 14.1 0.0 0.1 12.5 0.0 1.8 1 1 0 1 1 1 0 CAMSAP CH domain NEMO PF11577.8 CDJ85424.1 - 0.062 13.3 2.0 0.17 11.9 2.0 1.7 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO MutS_V PF00488.21 CDJ85425.1 - 9.3e-74 247.5 0.2 1.5e-73 246.9 0.2 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CDJ85425.1 - 1.2e-15 58.2 0.8 2.8e-15 57.1 0.8 1.5 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 CDJ85425.1 - 1.2e-12 47.9 0.1 2.7e-12 46.9 0.1 1.5 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 CDJ85425.1 - 2.7e-06 27.7 0.0 7.6e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 MutS domain II MutS_I PF01624.20 CDJ85425.1 - 5.2e-06 26.7 0.0 1.5e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 MutS domain I AAA_28 PF13521.6 CDJ85425.1 - 0.034 14.4 0.0 0.079 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain GAS PF13851.6 CDJ85427.1 - 0.0059 16.0 2.9 0.0077 15.6 2.9 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DHR10 PF18595.1 CDJ85427.1 - 0.033 14.3 3.5 0.042 13.9 3.5 1.1 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain MFP2b PF12150.8 CDJ85428.1 - 4.9e-130 433.8 0.3 5.7e-130 433.6 0.3 1.0 1 0 0 1 1 1 1 Cytosolic motility protein Tubulin PF00091.25 CDJ85429.1 - 1.9e-67 227.3 0.0 2.6e-67 226.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDJ85429.1 - 2.8e-50 169.7 0.0 4.9e-50 168.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CDJ85429.1 - 0.0011 18.6 0.0 0.0023 17.7 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Wbp11 PF09429.10 CDJ85430.1 - 0.042 14.2 2.4 0.057 13.8 2.4 1.2 1 0 0 1 1 1 0 WW domain binding protein 11 Ribosomal_L38e PF01781.18 CDJ85430.1 - 0.91 9.7 3.6 3.8 7.7 0.0 2.6 3 0 0 3 3 3 0 Ribosomal L38e protein family 7tm_1 PF00001.21 CDJ85431.1 - 4.1e-11 42.7 20.8 5.6e-11 42.3 20.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MIP PF00230.20 CDJ85433.1 - 1.8e-50 171.8 19.3 2.5e-50 171.3 19.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF2085 PF09858.9 CDJ85433.1 - 8.5 6.9 13.6 6 7.4 2.0 3.1 2 2 1 3 3 3 0 Predicted membrane protein (DUF2085) IP_trans PF02121.18 CDJ85434.1 - 1.7e-90 303.0 0.1 1.9e-90 302.8 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein PRELI PF04707.14 CDJ85434.1 - 0.08 12.8 0.1 2.9 7.7 0.0 2.2 2 0 0 2 2 2 0 PRELI-like family Coatomer_WDAD PF04053.14 CDJ85435.1 - 5.6e-134 447.5 0.6 7.8e-134 447.1 0.2 1.4 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 CDJ85435.1 - 2e-40 136.0 25.7 1.4e-07 32.1 0.1 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ85435.1 - 2e-10 40.8 1.7 0.00094 19.4 0.0 5.5 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDJ85435.1 - 0.86 8.2 3.9 1.6 7.3 0.2 3.1 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Dynein_light PF01221.18 CDJ85436.1 - 5.4e-25 87.5 0.7 6e-25 87.4 0.7 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Metallophos PF00149.28 CDJ85437.1 - 8.8e-33 114.5 0.0 1.3e-32 114.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDJ85437.1 - 8.2e-06 26.2 0.0 1.5e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain TMEM154 PF15102.6 CDJ85438.1 - 0.00018 21.4 3.3 0.00018 21.4 3.3 2.6 2 2 0 2 2 2 1 TMEM154 protein family Rax2 PF12768.7 CDJ85438.1 - 0.00038 20.0 0.0 0.00058 19.4 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity EphA2_TM PF14575.6 CDJ85438.1 - 0.0054 17.6 0.1 0.016 16.1 0.1 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 CDJ85438.1 - 0.025 14.9 0.0 0.064 13.6 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) Amnionless PF14828.6 CDJ85438.1 - 0.026 13.4 0.0 0.034 13.0 0.0 1.1 1 0 0 1 1 1 0 Amnionless Herpes_gE PF02480.16 CDJ85438.1 - 0.027 13.2 0.1 0.047 12.4 0.1 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF2207 PF09972.9 CDJ85438.1 - 0.061 12.1 0.0 0.087 11.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2970 PF11174.8 CDJ85438.1 - 0.091 12.6 2.6 0.17 11.8 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Cadherin_C_2 PF16492.5 CDJ85438.1 - 0.12 13.1 0.0 0.36 11.6 0.0 1.8 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal OAD_gamma PF04277.13 CDJ85438.1 - 0.13 12.9 0.3 0.13 12.9 0.3 3.8 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain NfeD PF01957.18 CDJ85438.1 - 0.35 11.3 3.4 2.8 8.4 3.4 2.4 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding Zip PF02535.22 CDJ85439.1 - 2.5 7.3 4.6 3.2 6.9 4.6 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter Nucleoside_tran PF01733.18 CDJ85441.1 - 6.6e-58 196.5 25.9 5.3e-26 91.7 6.1 3.6 2 1 2 4 4 4 4 Nucleoside transporter CCAP PF11105.8 CDJ85441.1 - 0.18 11.8 0.1 0.31 11.0 0.1 1.4 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a NrsF PF06532.11 CDJ85441.1 - 0.28 10.9 6.5 4.6 6.9 0.2 2.8 3 0 0 3 3 3 0 Negative regulator of sigma F RVT_1 PF00078.27 CDJ85442.1 - 1.4e-14 54.1 0.0 1.5e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CH PF00307.31 CDJ85442.1 - 0.09 13.0 0.1 8.8 6.6 0.0 2.1 1 1 1 2 2 2 0 Calponin homology (CH) domain Pyr_redox_2 PF07992.14 CDJ85443.1 - 3.4e-82 276.0 8.2 2.9e-66 223.7 3.7 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CDJ85443.1 - 6.1e-41 139.1 0.3 3.3e-40 136.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain FAD_oxidored PF12831.7 CDJ85443.1 - 4.9e-22 78.9 8.7 5.9e-10 39.1 0.0 3.9 3 1 1 4 4 4 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 CDJ85443.1 - 7.8e-21 74.4 12.4 3.1e-16 59.7 0.8 4.1 4 0 0 4 4 3 3 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CDJ85443.1 - 9.4e-18 64.5 10.4 1.6e-07 30.8 0.5 4.1 4 0 0 4 4 4 2 FAD binding domain Pyr_redox_3 PF13738.6 CDJ85443.1 - 5.2e-16 58.8 7.2 3.4e-13 49.5 0.8 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CDJ85443.1 - 5.9e-16 58.5 7.1 5.6e-07 29.0 0.2 3.4 3 0 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 CDJ85443.1 - 3.4e-13 49.6 3.1 0.00066 19.9 0.1 3.5 3 0 0 3 3 3 3 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CDJ85443.1 - 1.4e-12 47.3 2.1 6.3e-05 22.3 0.0 3.1 3 0 0 3 3 3 2 Thi4 family AlaDh_PNT_C PF01262.21 CDJ85443.1 - 1.8e-11 43.8 9.4 0.0051 16.1 0.3 3.4 3 0 0 3 3 3 3 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 CDJ85443.1 - 4.1e-11 42.7 11.8 0.01 15.1 0.0 4.2 4 0 0 4 4 4 3 FAD binding domain HI0933_like PF03486.14 CDJ85443.1 - 1.6e-10 40.3 17.8 0.00061 18.6 0.9 4.4 5 0 0 5 5 5 3 HI0933-like protein K_oxygenase PF13434.6 CDJ85443.1 - 2.2e-05 23.8 3.6 0.11 11.6 0.2 3.5 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 CDJ85443.1 - 0.0003 20.2 4.1 1.1 8.6 0.3 3.7 3 1 1 4 4 4 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CDJ85443.1 - 0.00097 18.8 10.4 1.9 8.0 0.7 4.1 3 1 0 3 3 3 3 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.6 CDJ85443.1 - 0.0023 18.4 0.1 30 5.1 0.1 3.9 4 0 0 4 4 4 0 XdhC Rossmann domain UPF0227 PF05728.12 CDJ85443.1 - 0.0026 17.7 0.0 2.3 8.1 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0227) 3HCDH_N PF02737.18 CDJ85443.1 - 0.01 15.7 2.6 0.6 10.0 0.4 3.2 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 CDJ85443.1 - 0.014 15.0 19.8 0.17 11.4 0.0 4.8 3 2 0 5 5 5 0 FAD dependent oxidoreductase HEM4 PF02602.15 CDJ85443.1 - 0.018 14.4 0.2 6.6 6.0 0.0 2.5 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD PSI_PSAK PF01241.18 CDJ85443.1 - 0.018 15.0 0.1 11 6.1 0.0 2.8 2 0 0 2 2 2 0 Photosystem I psaG / psaK Lycopene_cycl PF05834.12 CDJ85443.1 - 0.034 13.2 12.1 0.88 8.5 0.4 3.9 4 0 0 4 4 4 0 Lycopene cyclase protein THF_DHG_CYH_C PF02882.19 CDJ85443.1 - 0.07 12.4 4.5 3.7 6.9 0.1 4.0 5 0 0 5 5 5 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Trp_halogenase PF04820.14 CDJ85443.1 - 0.16 10.8 3.0 6.7 5.4 0.2 2.5 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.18 CDJ85443.1 - 5.6 7.3 5.2 1.5e+02 2.7 0.1 3.3 3 0 0 3 3 3 0 TrkA-N domain 7TM_GPCR_Srw PF10324.9 CDJ85445.1 - 1.3e-06 28.0 8.6 2.3e-06 27.2 8.6 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF4401 PF14351.6 CDJ85445.1 - 1.6e-06 27.7 0.0 3.2e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4401) SUR7 PF06687.12 CDJ85445.1 - 2.1 7.9 9.3 2.6 7.6 0.5 2.6 3 0 0 3 3 3 0 SUR7/PalI family Collagen PF01391.18 CDJ85446.1 - 1.4e-15 56.8 92.3 1.8e+04 -13.8 92.3 3.0 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ85446.1 - 0.086 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain ANAPC_CDC26 PF10471.9 CDJ85446.1 - 4.8 8.1 7.8 7.5 7.5 7.8 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Collagen PF01391.18 CDJ85448.1 - 6.1e-12 45.1 107.0 2.3e-07 30.5 47.2 3.7 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ85448.1 - 1.2e-08 34.9 0.2 1.6e-08 34.5 0.2 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ85449.1 - 5.9e-19 67.6 115.1 2.2e-08 33.7 45.3 3.9 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ85449.1 - 1.3e-10 41.2 0.5 1.7e-10 40.8 0.5 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ85450.1 - 7.4e-24 83.3 109.2 2.3e-08 33.6 32.8 4.8 3 2 1 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ85450.1 - 3.8e-07 30.1 0.0 5.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Col_cuticle_N PF01484.17 CDJ85451.1 - 6.9e-10 38.8 0.9 9.6e-10 38.4 0.9 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ85451.1 - 2.7e-08 33.4 84.8 1.6e-05 24.6 39.5 4.7 2 1 2 4 4 4 3 Collagen triple helix repeat (20 copies) 7tm_1 PF00001.21 CDJ85452.1 - 1.3e-12 47.6 9.9 1.3e-12 47.6 9.9 1.6 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CDJ85452.1 - 1.6e-06 28.0 13.0 2.5e-06 27.3 13.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF1980 PF09323.10 CDJ85452.1 - 1.9 8.4 6.4 0.3 11.0 1.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Guanylate_cyc PF00211.20 CDJ85453.1 - 9.4e-65 217.7 0.0 1.5e-64 217.0 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 CDJ85453.1 - 2.4e-37 128.6 0.0 4.3e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ85453.1 - 2.1e-31 109.3 0.0 5.2e-31 108.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain ANF_receptor PF01094.28 CDJ85453.1 - 1.5e-11 44.0 0.0 5.6e-11 42.1 0.0 1.8 2 0 0 2 2 2 1 Receptor family ligand binding region HNOBA PF07701.14 CDJ85453.1 - 0.00026 20.5 1.7 0.00045 19.7 1.7 1.4 1 0 0 1 1 1 1 Heme NO binding associated Kinase-like PF14531.6 CDJ85453.1 - 0.011 15.1 0.1 0.026 13.8 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Scm3 PF10384.9 CDJ85453.1 - 0.77 9.5 2.6 39 4.1 0.0 3.3 3 0 0 3 3 3 0 Centromere protein Scm3 HTH_26 PF13443.6 CDJ85456.1 - 0.0014 19.0 0.0 0.0019 18.6 0.0 1.2 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_IclR PF09339.10 CDJ85456.1 - 0.0016 18.2 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_3 PF01381.22 CDJ85456.1 - 0.0043 17.1 0.0 0.0092 16.0 0.0 1.5 2 0 0 2 2 2 1 Helix-turn-helix HTH_23 PF13384.6 CDJ85456.1 - 0.0054 16.5 1.1 0.013 15.3 0.2 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 CDJ85456.1 - 0.028 15.0 0.7 0.035 14.7 0.7 1.1 1 0 0 1 1 1 0 Homeodomain-like domain MarR_2 PF12802.7 CDJ85456.1 - 0.051 13.5 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 MarR family LacI PF00356.21 CDJ85456.1 - 0.17 11.7 0.6 0.66 9.8 0.1 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Y_phosphatase PF00102.27 CDJ85457.1 - 5.8e-16 58.8 0.0 7.7e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF1774 PF08611.10 CDJ85458.1 - 0.019 15.3 0.9 0.048 14.0 0.0 1.9 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1774) DUF4199 PF13858.6 CDJ85458.1 - 0.085 13.3 4.4 1.8 9.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Orf78 PF06024.12 CDJ85458.1 - 0.13 12.5 2.1 4.1 7.7 0.1 2.2 2 0 0 2 2 2 0 Orf78 (ac78) Gram_pos_anchor PF00746.21 CDJ85458.1 - 1.3 9.1 0.1 1.3 9.1 0.1 2.6 3 0 0 3 3 3 0 LPXTG cell wall anchor motif Peptidase_M48_N PF16491.5 CDJ85458.1 - 2.2 8.1 8.5 3.2 7.6 2.6 2.0 2 0 0 2 2 2 0 CAAX prenyl protease N-terminal, five membrane helices BBS2_Mid PF14783.6 CDJ85459.1 - 0.004 17.2 0.0 0.013 15.6 0.0 1.8 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region BBS2_C PF14782.6 CDJ85459.1 - 0.015 14.1 0.2 0.024 13.4 0.2 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Pox_A_type_inc PF04508.12 CDJ85459.1 - 0.12 12.3 1.2 0.29 11.0 1.2 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Y_phosphatase PF00102.27 CDJ85460.1 - 6.5e-72 241.9 0.1 8.4e-72 241.5 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CDJ85460.1 - 0.00032 20.8 0.1 0.00065 19.7 0.1 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 CDJ85460.1 - 0.0004 20.0 0.0 0.0012 18.5 0.0 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CDJ85460.1 - 0.00067 19.5 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF148 PF02520.17 CDJ85461.1 - 2.1e-13 50.3 1.9 2.9e-13 49.9 1.9 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF148 Bromo_TP PF07524.13 CDJ85463.1 - 2e-16 59.8 0.0 6.5e-16 58.1 0.0 1.9 2 0 0 2 2 2 1 Bromodomain associated TAF8_C PF10406.9 CDJ85463.1 - 1.2e-14 54.6 1.1 8.2e-14 51.9 1.0 2.6 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP_like PF17027.5 CDJ85463.1 - 0.19 11.9 0.0 0.68 10.1 0.0 1.9 2 0 0 2 2 2 0 Histone-fold protein AA_permease_2 PF13520.6 CDJ85464.1 - 1.1e-113 380.3 94.8 1.2e-58 199.0 43.8 2.2 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 CDJ85464.1 - 1.3e-56 192.2 84.8 1.4e-29 103.1 38.3 2.4 2 1 0 2 2 2 2 Amino acid permease YidD PF01809.18 CDJ85464.1 - 0.019 14.8 0.0 5.6 6.9 0.0 2.5 2 0 0 2 2 2 0 Putative membrane protein insertion efficiency factor DUF410 PF04190.13 CDJ85465.1 - 3.3e-51 174.6 0.5 4.1e-51 174.2 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) IFRD PF05004.13 CDJ85465.1 - 0.036 13.2 0.4 0.036 13.2 0.4 1.9 2 1 0 2 2 2 0 Interferon-related developmental regulator (IFRD) PAH PF02671.21 CDJ85465.1 - 0.068 13.3 0.6 10 6.4 0.1 3.3 2 1 1 3 3 3 0 Paired amphipathic helix repeat TPR_2 PF07719.17 CDJ85465.1 - 0.21 11.8 4.0 22 5.5 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Flavodoxin_1 PF00258.25 CDJ85466.1 - 3.9e-28 98.5 0.0 7.6e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 CDJ85466.1 - 2.8e-27 95.8 0.0 4.9e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 CDJ85466.1 - 1.5e-09 38.5 0.0 2.9e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 CDJ85466.1 - 0.064 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain NAD_binding_6 PF08030.12 CDJ85466.1 - 0.18 11.9 0.0 0.66 10.1 0.0 1.9 2 0 0 2 2 2 0 Ferric reductase NAD binding domain DSPn PF14671.6 CDJ85467.1 - 1.9e-33 115.9 0.0 5.1e-33 114.5 0.0 1.8 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 CDJ85467.1 - 9.2e-16 57.9 0.0 3.5e-14 52.8 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CDJ85467.1 - 4.4e-06 26.9 0.0 8.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 CDJ85467.1 - 7.1e-06 25.8 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CDJ85467.1 - 0.01 15.8 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF442 PF04273.13 CDJ85467.1 - 0.15 12.2 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative phosphatase (DUF442) Y_phosphatase2 PF03162.13 CDJ85467.1 - 0.2 11.2 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF780 PF05611.11 CDJ85468.1 - 2.8e-07 31.2 29.4 1.8e-05 25.4 29.4 2.2 1 1 0 1 1 1 1 Caenorhabditis elegans protein of unknown function (DUF780) DUF780 PF05611.11 CDJ85469.1 - 5.4e-08 33.5 19.9 5.4e-08 33.5 19.9 2.2 1 1 0 2 2 2 2 Caenorhabditis elegans protein of unknown function (DUF780) DUF148 PF02520.17 CDJ85470.1 - 1.9e-13 50.4 4.1 2.8e-13 49.9 4.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF148 Lipase_chap PF03280.14 CDJ85470.1 - 0.00061 19.8 9.9 0.17 11.8 5.0 2.3 1 1 1 2 2 2 2 Proteobacterial lipase chaperone protein HMG_box PF00505.19 CDJ85470.1 - 0.017 15.5 1.8 4 7.9 0.0 2.7 1 1 0 2 2 2 0 HMG (high mobility group) box OSCP PF00213.18 CDJ85470.1 - 0.052 13.7 1.0 4.9 7.3 0.0 2.1 1 1 1 2 2 2 0 ATP synthase delta (OSCP) subunit Lebercilin PF15619.6 CDJ85470.1 - 0.059 13.0 3.3 0.087 12.5 3.3 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF3106 PF11304.8 CDJ85470.1 - 0.096 13.2 4.4 0.2 12.2 4.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) DUF4233 PF14017.6 CDJ85470.1 - 0.32 11.4 1.3 0.49 10.8 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) ZYG-11_interact PF05884.12 CDJ85471.1 - 5.9e-30 104.7 4.4 6.9e-30 104.5 4.4 1.0 1 0 0 1 1 1 1 Interactor of ZYG-11 CAP PF00188.26 CDJ85472.1 - 4.3e-20 72.8 3.5 1.2e-09 39.0 0.0 3.0 3 0 0 3 3 3 2 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ85472.1 - 0.065 13.5 1.0 2 8.8 0.0 2.6 2 1 0 2 2 2 0 Ancylostoma-associated secreted protein related DUF2569 PF10754.9 CDJ85473.1 - 0.4 11.1 17.6 0.86 10.0 17.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) Peptidase_U4 PF03419.13 CDJ85473.1 - 0.52 9.6 15.8 0.66 9.2 15.8 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA TssN PF17555.2 CDJ85473.1 - 5.8 6.2 18.8 0.29 10.5 2.6 2.1 1 1 1 2 2 2 0 Type VI secretion system, TssN Yip1 PF04893.17 CDJ85473.1 - 7.4 6.2 18.0 0.63 9.7 2.6 2.1 1 1 1 2 2 2 0 Yip1 domain DUF2070 PF09843.9 CDJ85473.1 - 8.9 4.5 17.3 13 4.0 17.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Linker_histone PF00538.19 CDJ85474.1 - 3.4e-25 88.2 0.5 8.8e-25 86.9 0.5 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family RHH_1 PF01402.21 CDJ85474.1 - 0.019 14.9 0.0 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family RT_RNaseH PF17917.1 CDJ85475.1 - 5.9e-32 110.1 0.0 1.3e-31 109.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ85475.1 - 5.9e-31 106.5 0.0 1.6e-30 105.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ85475.1 - 3e-20 72.6 0.0 1.4e-18 67.2 0.0 2.9 3 0 0 3 3 3 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ85475.1 - 9.9e-16 57.6 1.1 9.9e-16 57.6 1.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 CDJ85475.1 - 5.3e-11 42.5 0.1 8.6e-11 41.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 CDJ85475.1 - 0.0016 18.2 0.0 0.0041 16.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain ZYG-11_interact PF05884.12 CDJ85477.1 - 4.8e-17 62.3 4.2 7.4e-17 61.7 4.2 1.3 1 1 0 1 1 1 1 Interactor of ZYG-11 SRP54_N PF02881.19 CDJ85478.1 - 0.0099 16.1 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CAP PF00188.26 CDJ85479.1 - 2.4e-15 57.5 2.6 2.4e-15 57.5 2.6 1.6 2 0 0 2 2 2 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ85479.1 - 0.012 15.9 0.9 0.18 12.1 0.9 2.2 1 1 0 1 1 1 0 Ancylostoma-associated secreted protein related Sof1 PF04158.14 CDJ85480.1 - 4.9e-26 90.8 5.8 1.1e-25 89.8 5.8 1.6 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 CDJ85480.1 - 3.3e-16 59.4 12.6 3.9e-05 24.3 0.0 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ85480.1 - 0.00023 21.4 0.1 0.023 15.0 0.0 2.9 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Inositol_P PF00459.25 CDJ85481.1 - 1.1e-42 146.4 1.3 2.9e-42 145.1 1.3 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family FrhB_FdhB_C PF04432.13 CDJ85481.1 - 0.03 14.1 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus DUF5081 PF16887.5 CDJ85481.1 - 0.049 12.7 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5081) CagE_TrbE_VirB PF03135.14 CDJ85481.1 - 0.15 12.1 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system Pro_dh PF01619.18 CDJ85482.1 - 3.4e-40 138.4 0.0 7.2e-39 134.1 0.0 2.0 1 1 0 1 1 1 1 Proline dehydrogenase EF-hand_7 PF13499.6 CDJ85482.1 - 0.00077 19.9 0.7 0.002 18.5 0.2 1.9 2 0 0 2 2 2 1 EF-hand domain pair Acetyltransf_14 PF03421.16 CDJ85482.1 - 0.0075 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 YopJ Serine/Threonine acetyltransferase EF-hand_6 PF13405.6 CDJ85482.1 - 0.0082 16.0 1.2 0.019 14.9 0.3 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CDJ85482.1 - 0.025 14.1 2.9 0.12 11.9 0.4 2.8 2 0 0 2 2 2 0 EF hand Herpes_UL25 PF01499.16 CDJ85482.1 - 0.039 12.5 0.0 0.054 12.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family NPHI_C PF08469.10 CDJ85482.1 - 0.073 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Nucleoside triphosphatase I C-terminal EF-hand_8 PF13833.6 CDJ85482.1 - 0.1 12.4 0.5 0.3 11.0 0.2 1.9 2 0 0 2 2 2 0 EF-hand domain pair FG-GAP PF01839.23 CDJ85482.1 - 0.3 11.3 1.3 0.54 10.4 1.3 1.3 1 0 0 1 1 1 0 FG-GAP repeat Aa_trans PF01490.18 CDJ85484.1 - 7.3e-67 225.8 32.2 2.4e-51 174.8 25.0 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Aa_trans PF01490.18 CDJ85485.1 - 4e-35 121.3 12.3 4.4e-34 117.9 4.7 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein DUF4229 PF14012.6 CDJ85485.1 - 0.85 9.8 9.5 0.51 10.5 6.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4229) Pkinase PF00069.25 CDJ85486.1 - 1.2e-20 74.0 0.0 1.5e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ85486.1 - 1.7e-11 43.9 0.0 2.9e-11 43.2 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ85486.1 - 0.0073 15.1 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDJ85486.1 - 0.027 14.4 0.0 0.31 10.9 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family WBP-1 PF11669.8 CDJ85487.1 - 0.018 15.7 0.4 0.026 15.1 0.3 1.3 1 1 0 1 1 1 0 WW domain-binding protein 1 MMPL PF03176.15 CDJ85488.1 - 1.3e-07 30.8 11.5 4.2e-07 29.2 11.5 1.7 1 1 0 1 1 1 1 MMPL family Patched PF02460.18 CDJ85488.1 - 6e-07 28.0 5.5 6e-07 28.0 5.5 2.4 2 1 1 3 3 3 1 Patched family Sterol-sensing PF12349.8 CDJ85488.1 - 0.00074 19.4 12.1 0.00074 19.4 12.1 2.8 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MHC_I_2 PF14586.6 CDJ85488.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 ACR_tran PF00873.19 CDJ85488.1 - 3.4 5.2 17.9 0.76 7.3 13.8 1.7 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family AAA_11 PF13086.6 CDJ85490.1 - 0.0039 17.0 0.0 0.027 14.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 CDJ85490.1 - 0.04 13.5 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CDJ85490.1 - 0.15 11.7 0.0 3.1 7.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Ion_trans_2 PF07885.16 CDJ85492.1 - 8.9e-28 96.1 21.7 1.6e-15 56.8 2.2 2.7 3 0 0 3 3 3 2 Ion channel fn3 PF00041.21 CDJ85492.1 - 1.3e-14 54.3 0.2 4.5e-07 30.1 0.0 2.4 2 0 0 2 2 2 2 Fibronectin type III domain Ion_trans PF00520.31 CDJ85492.1 - 3.5e-07 29.7 2.0 0.0001 21.6 0.0 2.3 2 0 0 2 2 2 2 Ion transport protein DUF4271 PF14093.6 CDJ85492.1 - 0.0014 18.6 1.8 1 9.2 0.0 2.7 2 1 1 3 3 3 2 Domain of unknown function (DUF4271) 7TM_GPCR_Sri PF10327.9 CDJ85492.1 - 0.0069 15.6 1.4 0.017 14.3 1.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri Lig_chan PF00060.26 CDJ85492.1 - 0.025 14.4 1.2 0.12 12.2 0.0 2.5 2 1 0 2 2 2 0 Ligand-gated ion channel DUF3852 PF12963.7 CDJ85492.1 - 0.22 11.9 1.1 21 5.5 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3852) Peptidase_C54 PF03416.19 CDJ85493.1 - 1.1e-76 257.9 0.0 1.5e-76 257.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 His_Phos_2 PF00328.22 CDJ85494.1 - 9.8e-11 41.6 0.1 2.3e-07 30.5 0.1 2.2 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) bZIP_1 PF00170.21 CDJ85495.1 - 0.0067 16.5 2.5 0.0067 16.5 2.5 6.8 4 2 3 7 7 7 2 bZIP transcription factor Fez1 PF06818.15 CDJ85495.1 - 0.015 15.7 13.3 0.015 15.7 13.3 3.4 2 2 1 3 3 3 0 Fez1 DUF1664 PF07889.12 CDJ85495.1 - 0.034 14.2 18.6 0.15 12.1 2.2 4.4 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 CDJ85495.1 - 0.091 13.2 8.7 0.18 12.2 0.1 4.5 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF1493 PF07377.12 CDJ85495.1 - 0.43 11.1 3.2 24 5.4 0.1 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1493) NDUF_B6 PF09782.9 CDJ85496.1 - 2.9e-52 177.0 2.1 3.3e-52 176.7 2.1 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit SUI1 PF01253.22 CDJ85497.1 - 4.4e-15 56.0 0.1 9.2e-15 54.9 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 CDJ85497.1 - 2e-14 54.0 0.1 1.1e-13 51.7 0.0 2.3 2 0 0 2 2 2 1 Pre-PUA-like domain PUA PF01472.20 CDJ85497.1 - 2.3e-07 30.7 0.0 4.7e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 PUA domain NotI PF12183.8 CDJ85497.1 - 0.046 13.0 0.1 0.087 12.1 0.1 1.4 1 0 0 1 1 1 0 Restriction endonuclease NotI 4HBT PF03061.22 CDJ85498.1 - 3.4e-15 56.2 0.4 5.3e-15 55.5 0.4 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 CDJ85498.1 - 7e-06 26.5 0.2 8.8e-06 26.2 0.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.6 CDJ85498.1 - 0.027 14.6 0.0 0.037 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) MxiM PF11441.8 CDJ85498.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Pilot protein MxiM DUF4494 PF14902.6 CDJ85501.1 - 0.02 14.7 0.1 0.026 14.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4494) RsbRD_N PF14361.6 CDJ85501.1 - 0.026 15.2 0.1 0.047 14.4 0.1 1.4 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain Tropomyosin PF00261.20 CDJ85501.1 - 0.064 12.6 0.0 0.091 12.1 0.0 1.3 1 1 0 1 1 1 0 Tropomyosin Diphthami_syn_2 PF01902.17 CDJ85502.1 - 3e-34 118.4 0.1 5.1e-34 117.7 0.1 1.3 1 1 0 1 1 1 1 Diphthamide synthase Macin PF14865.6 CDJ85503.1 - 8.2e-07 29.5 14.2 1.5e-06 28.6 14.3 1.4 1 1 0 1 1 1 1 Macin Cauli_VI PF01693.16 CDJ85503.1 - 0.19 12.1 0.2 0.19 12.1 0.2 1.6 2 0 0 2 2 2 0 Caulimovirus viroplasmin Arylesterase PF01731.20 CDJ85505.1 - 3.5e-08 33.5 0.8 1.9e-07 31.2 0.4 2.3 2 0 0 2 2 2 1 Arylesterase SGL PF08450.12 CDJ85505.1 - 3.3e-06 26.9 0.0 4.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 CDJ85505.1 - 0.032 14.4 0.0 0.071 13.2 0.0 1.6 1 0 0 1 1 1 0 Strictosidine synthase Memo PF01875.17 CDJ85505.1 - 0.11 11.6 0.0 0.25 10.4 0.0 1.5 1 0 0 1 1 1 0 Memo-like protein Arylesterase PF01731.20 CDJ85506.1 - 1.3e-18 66.9 0.0 1.2e-16 60.6 0.0 2.9 3 0 0 3 3 3 2 Arylesterase RVT_1 PF00078.27 CDJ85508.1 - 4.1e-43 147.5 0.0 6.6e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ULD PF16534.5 CDJ85509.1 - 5e-21 74.8 0.0 9.2e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like oligomerisation domain of SATB Homeodomain PF00046.29 CDJ85509.1 - 2.9e-15 55.8 3.5 3.5e-10 39.6 0.2 3.0 2 1 0 2 2 2 2 Homeodomain Homeobox_KN PF05920.11 CDJ85509.1 - 0.0025 17.7 3.1 0.055 13.4 0.5 3.5 3 0 0 3 3 3 1 Homeobox KN domain Homez PF11569.8 CDJ85509.1 - 0.022 14.2 0.2 0.57 9.7 0.1 2.5 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez HipN PF18253.1 CDJ85509.1 - 0.14 11.8 0.0 5.1 6.9 0.0 2.5 1 1 1 2 2 2 0 Hsp70-interacting protein N N-terminal domain HECW_N PF16562.5 CDJ85510.1 - 2.9e-17 62.6 0.0 3.9e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 CDJ85510.1 - 0.021 15.4 0.0 0.051 14.1 0.0 1.6 1 1 0 1 1 1 0 SKICH domain RVT_1 PF00078.27 CDJ85511.1 - 1.3e-09 37.9 0.0 2.8e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Shikimate_dh_N PF08501.11 CDJ85511.1 - 0.096 13.0 0.0 0.29 11.4 0.0 1.9 1 1 1 2 2 2 0 Shikimate dehydrogenase substrate binding domain 7tm_1 PF00001.21 CDJ85512.1 - 4.2e-07 29.5 10.9 8.2e-07 28.6 10.5 1.6 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) Xan_ur_permease PF00860.20 CDJ85512.1 - 1.4 7.5 6.8 2.9 6.5 0.5 2.6 1 1 2 3 3 3 0 Permease family Bestrophin PF01062.21 CDJ85513.1 - 5e-79 265.8 8.3 5.7e-79 265.6 8.3 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel RabGAP-TBC PF00566.18 CDJ85514.1 - 1.6e-48 165.2 2.2 2.2e-48 164.8 2.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ELMO_CED12 PF04727.13 CDJ85514.1 - 0.01 15.9 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 0 ELMO/CED-12 family Mo-nitro_C PF06967.11 CDJ85514.1 - 0.078 13.0 0.1 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 Mo-dependent nitrogenase C-terminus HSL_N PF06350.12 CDJ85515.1 - 5.6e-88 294.8 0.0 1e-87 294.0 0.0 1.5 1 0 0 1 1 1 1 Hormone-sensitive lipase (HSL) N-terminus Abhydrolase_3 PF07859.13 CDJ85515.1 - 1.4e-38 132.9 0.1 5.4e-27 95.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CDJ85515.1 - 9.7e-06 24.7 0.0 2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Steryl acetyl hydrolase HTH_48 PF17906.1 CDJ85517.1 - 0.024 14.8 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 HTH domain in Mos1 transposase zf-C4 PF00105.18 CDJ85518.1 - 1.5e-27 95.8 16.2 2.2e-27 95.3 16.2 1.2 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF3568 PF12092.8 CDJ85519.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3568) Pneumo_att_G PF05539.11 CDJ85520.1 - 2.5 7.6 27.8 4.1 6.9 27.8 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Calsequestrin PF01216.17 CDJ85521.1 - 3.7e-62 210.6 20.8 4.3e-62 210.3 20.8 1.0 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_6 PF13848.6 CDJ85521.1 - 5e-15 55.9 4.7 4.1e-14 52.9 0.0 2.6 2 2 1 3 3 3 2 Thioredoxin-like domain Na_Pi_cotrans PF02690.15 CDJ85522.1 - 1.1e-25 90.4 31.5 1.1e-16 61.2 5.3 3.3 3 1 0 4 4 4 2 Na+/Pi-cotransporter DUF2207 PF09972.9 CDJ85522.1 - 0.0033 16.3 17.1 0.099 11.4 0.1 3.1 3 0 0 3 3 3 3 Predicted membrane protein (DUF2207) Claudin_2 PF13903.6 CDJ85523.1 - 1.6e-05 24.7 7.9 2.5e-05 24.1 7.9 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction HTH_48 PF17906.1 CDJ85525.1 - 2.5e-18 65.9 0.4 3.7e-18 65.4 0.4 1.3 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 CDJ85525.1 - 0.022 15.4 0.1 0.042 14.4 0.0 1.5 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 CDJ85525.1 - 0.052 13.7 0.0 0.13 12.4 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 CDJ85525.1 - 0.13 12.1 0.2 0.4 10.5 0.0 1.9 3 0 0 3 3 3 0 Homeodomain-like domain Piwi PF02171.17 CDJ85526.1 - 7.3e-68 229.0 0.0 1.2e-67 228.3 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 CDJ85526.1 - 1.1e-33 115.4 1.3 1.6e-33 114.8 0.3 1.9 2 0 0 2 2 2 1 Mid domain of argonaute PAZ PF02170.22 CDJ85526.1 - 2.1e-28 98.8 1.8 8.5e-25 87.2 0.5 2.4 1 1 1 2 2 2 2 PAZ domain ArgoN PF16486.5 CDJ85526.1 - 2.5e-28 99.4 0.0 6.2e-28 98.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 CDJ85526.1 - 2.5e-22 78.3 0.0 5.1e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 CDJ85526.1 - 1.6e-12 47.6 0.0 3.5e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain TMEM189_B_dmain PF10520.9 CDJ85528.1 - 1.9e-69 233.2 9.9 1.9e-69 233.2 9.9 1.6 2 0 0 2 2 2 1 B domain of TMEM189, localisation domain DUF2157 PF09925.9 CDJ85528.1 - 0.0042 16.9 0.2 0.0087 15.8 0.2 1.5 1 1 0 1 1 1 1 Predicted membrane protein (DUF2157) DUF2892 PF11127.8 CDJ85528.1 - 0.0053 16.8 1.7 0.0076 16.3 0.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2892) Bax1-I PF01027.20 CDJ85528.1 - 0.66 9.8 6.8 0.11 12.2 1.6 1.9 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 CTP_transf_1 PF01148.20 CDJ85528.1 - 1.4 8.7 6.5 0.75 9.5 2.0 2.0 2 0 0 2 2 2 0 Cytidylyltransferase family DUF1104 PF06518.11 CDJ85529.1 - 0.18 12.2 4.9 0.26 11.7 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) 7TM_GPCR_Srab PF10292.9 CDJ85530.1 - 0.00025 20.1 1.5 0.00039 19.5 1.5 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor Sre PF03125.18 CDJ85530.1 - 0.013 14.7 3.9 0.036 13.2 3.7 1.7 1 1 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor SpoIIIAH PF12685.7 CDJ85531.1 - 0.00012 22.0 3.2 0.00012 22.0 3.2 2.6 2 1 0 2 2 1 1 SpoIIIAH-like protein TMEM154 PF15102.6 CDJ85531.1 - 0.0026 17.7 0.0 0.0026 17.7 0.0 3.6 2 1 1 3 3 2 1 TMEM154 protein family ABC_export PF16962.5 CDJ85531.1 - 0.0026 16.3 2.0 0.0036 15.8 2.0 1.2 1 0 0 1 1 1 1 Putative ABC exporter Mucin PF01456.17 CDJ85531.1 - 0.004 17.2 46.6 0.0056 16.7 26.9 3.1 2 1 1 3 3 3 2 Mucin-like glycoprotein AF-4 PF05110.13 CDJ85531.1 - 0.0044 15.2 23.6 0.0053 14.9 23.6 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein HemX PF04375.14 CDJ85531.1 - 0.0089 15.3 0.2 0.0089 15.3 0.2 1.6 2 0 0 2 2 2 1 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4366 PF14283.6 CDJ85531.1 - 0.019 15.0 0.1 0.019 15.0 0.1 3.3 2 1 1 3 3 2 0 Domain of unknown function (DUF4366) TrbL PF04610.14 CDJ85531.1 - 0.095 12.4 0.5 0.13 12.0 0.5 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein DUF5383 PF17355.2 CDJ85531.1 - 0.19 12.1 0.0 0.19 12.1 0.0 3.2 3 0 0 3 3 2 0 Family of unknown function (DUF5383) TRP PF06011.12 CDJ85531.1 - 0.22 10.2 2.3 0.21 10.3 1.4 1.4 1 1 0 1 1 1 0 Transient receptor potential (TRP) ion channel Orf78 PF06024.12 CDJ85531.1 - 1.4 9.2 0.0 1.4 9.2 0.0 3.1 3 0 0 3 3 3 0 Orf78 (ac78) CLN3 PF02487.17 CDJ85531.1 - 1.4 7.8 7.6 0.16 11.0 0.4 2.1 2 0 0 2 2 2 0 CLN3 protein V_ATPase_I PF01496.19 CDJ85531.1 - 2.6 5.9 11.2 0.028 12.4 1.2 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family SID-1_RNA_chan PF13965.6 CDJ85531.1 - 2.8 6.3 3.8 0.69 8.2 0.1 1.7 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Connexin PF00029.19 CDJ85531.1 - 3.2 7.5 15.5 2.3 7.9 9.2 2.5 2 1 0 2 2 2 0 Connexin PFEMP PF03011.15 CDJ85532.1 - 0.015 15.9 0.0 0.029 15.0 0.0 1.4 1 0 0 1 1 1 0 PFEMP DBL domain TMEM154 PF15102.6 CDJ85533.1 - 1.7e-06 28.0 0.1 3.6e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 TMEM154 protein family LRRC37AB_C PF14914.6 CDJ85533.1 - 0.012 15.5 0.1 0.019 14.9 0.1 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DUF5383 PF17355.2 CDJ85533.1 - 0.013 15.9 0.1 0.021 15.2 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5383) RIFIN PF02009.16 CDJ85533.1 - 0.013 15.4 0.4 0.019 14.8 0.4 1.2 1 0 0 1 1 1 0 Rifin DAG1 PF05454.11 CDJ85533.1 - 0.018 14.4 0.0 0.022 14.1 0.0 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Glycophorin_A PF01102.18 CDJ85533.1 - 0.019 15.2 0.1 0.032 14.5 0.1 1.5 1 0 0 1 1 1 0 Glycophorin A Vpu PF00558.19 CDJ85533.1 - 0.019 14.7 0.1 0.045 13.5 0.1 1.6 1 0 0 1 1 1 0 Vpu protein TMEM51 PF15345.6 CDJ85533.1 - 0.029 14.2 0.1 0.09 12.6 0.0 1.7 1 1 0 1 1 1 0 Transmembrane protein 51 DUF2207 PF09972.9 CDJ85533.1 - 0.045 12.5 0.0 0.081 11.7 0.0 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Amnionless PF14828.6 CDJ85533.1 - 0.066 12.0 0.0 0.082 11.7 0.0 1.1 1 0 0 1 1 1 0 Amnionless Orf78 PF06024.12 CDJ85533.1 - 0.07 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) PALP PF00291.25 CDJ85534.1 - 2.2e-17 63.4 0.1 2.5e-17 63.2 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_12 PF08242.12 CDJ85534.1 - 0.076 13.8 0.0 0.18 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain SPATA19 PF15212.6 CDJ85534.1 - 0.082 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 19, mitochondrial InaF-motif PF15018.6 CDJ85535.1 - 3.1e-16 59.0 6.6 4.3e-16 58.5 6.6 1.2 1 0 0 1 1 1 1 TRP-interacting helix 7tm_1 PF00001.21 CDJ85536.1 - 0.043 13.1 11.1 0.12 11.7 9.3 2.2 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) SLATT_5 PF18160.1 CDJ85536.1 - 1.1 8.5 11.7 1.2 8.4 0.5 2.5 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 JAB PF01398.21 CDJ85538.1 - 4.5e-32 110.5 0.0 7.6e-32 109.8 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 CDJ85538.1 - 5.8e-16 59.2 0.9 5.9e-15 56.0 0.0 2.7 2 2 0 2 2 2 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 CDJ85538.1 - 2.6e-05 24.0 0.0 5.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 CDJ85538.1 - 0.039 14.0 0.0 0.087 12.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Pkinase PF00069.25 CDJ85539.1 - 1.9e-66 224.1 0.0 2.3e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ85539.1 - 9.2e-33 113.6 0.0 1.4e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ85539.1 - 4.9e-06 26.1 0.0 7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CDJ85539.1 - 0.00013 21.1 0.0 0.00048 19.2 0.0 1.8 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CDJ85539.1 - 0.0012 18.9 0.2 0.014 15.4 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ85539.1 - 0.0034 16.8 0.2 0.02 14.3 0.2 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CDJ85539.1 - 0.066 12.3 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 TFIIE_beta PF02186.15 CDJ85541.1 - 1.6e-18 66.7 0.2 1.1e-17 64.0 0.0 2.3 2 0 0 2 2 2 1 TFIIE beta subunit core domain TFA2_Winged_2 PF18121.1 CDJ85541.1 - 4.5e-08 32.7 0.1 1.3e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 MecA_N PF05223.11 CDJ85541.1 - 0.00056 20.2 0.4 0.018 15.3 0.0 2.5 2 0 0 2 2 2 1 NTF2-like N-terminal transpeptidase domain PAXIP1_C PF15364.6 CDJ85541.1 - 0.067 13.5 0.5 0.067 13.5 0.5 1.7 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein FAD-oxidase_C PF02913.19 CDJ85542.1 - 4e-45 154.4 0.0 7.4e-45 153.5 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CDJ85542.1 - 5.3e-30 104.0 0.0 1.6e-29 102.4 0.0 1.9 1 0 0 1 1 1 1 FAD binding domain YnfE PF17452.2 CDJ85542.1 - 0.021 15.1 0.3 0.07 13.4 0.3 1.8 1 0 0 1 1 1 0 Uncharacterized YnfE-like DUF3877 PF12993.7 CDJ85542.1 - 0.021 14.7 0.1 0.094 12.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) Toprim_4 PF13662.6 CDJ85542.1 - 0.075 13.5 0.2 3.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Toprim domain COMPASS-Shg1 PF05205.12 CDJ85542.1 - 0.41 11.4 2.7 0.9 10.3 2.7 1.5 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 DUF2014 PF09427.10 CDJ85543.1 - 0.028 13.8 0.6 0.028 13.8 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2014) ApoO PF09769.9 CDJ85543.1 - 4.2 7.3 7.2 26 4.8 1.8 3.2 1 1 1 3 3 3 0 Apolipoprotein O YtxH PF12732.7 CDJ85543.1 - 5.5 7.6 45.7 1.2e+03 0.1 7.3 5.4 1 1 1 2 2 2 0 YtxH-like protein Phasin PF05597.11 CDJ85544.1 - 0.02 14.9 0.9 0.025 14.6 0.9 1.2 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Rpp20 PF12328.8 CDJ85544.1 - 0.082 12.9 3.2 0.098 12.6 3.2 1.1 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Ras PF00071.22 CDJ85546.1 - 1.2e-57 194.0 0.0 1.4e-57 193.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ85546.1 - 3.7e-23 82.0 0.0 6.1e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ85546.1 - 2e-10 40.4 0.0 3.9e-10 39.5 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDJ85546.1 - 0.00073 19.1 0.0 0.0014 18.2 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CDJ85546.1 - 0.014 14.8 0.1 0.062 12.7 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 CDJ85546.1 - 0.04 14.2 0.1 2.1 8.6 0.2 2.1 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 CDJ85546.1 - 0.052 12.9 0.0 0.064 12.6 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Urocanase_C PF17392.2 CDJ85547.1 - 1.8e-71 239.7 3.9 2e-71 239.5 3.9 1.0 1 0 0 1 1 1 1 Urocanase C-terminal domain Virulence_fact PF13769.6 CDJ85547.1 - 0.045 14.0 0.4 1.1 9.5 0.0 2.1 2 0 0 2 2 2 0 Virulence factor PRELI PF04707.14 CDJ85549.1 - 3.4e-46 156.9 0.0 6e-46 156.1 0.0 1.4 1 0 0 1 1 1 1 PRELI-like family CRAL_TRIO PF00650.20 CDJ85549.1 - 8e-41 139.4 0.0 6.8e-40 136.4 0.0 2.1 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CDJ85549.1 - 2.7e-06 27.5 1.8 8.3e-06 25.9 1.8 2.0 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain LRR_8 PF13855.6 CDJ85550.1 - 8.5e-29 99.1 16.0 8e-11 41.5 6.5 4.3 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 CDJ85550.1 - 1.9e-23 82.1 29.5 2.5e-05 24.6 0.0 5.6 1 1 7 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDJ85550.1 - 6.9e-09 35.0 16.0 34 5.5 0.0 9.1 8 1 1 9 9 9 2 Leucine Rich Repeat LRR_9 PF14580.6 CDJ85550.1 - 4.7e-08 32.7 7.8 0.0048 16.4 2.1 3.1 1 1 2 3 3 3 3 Leucine-rich repeat 5_nucleotid PF05761.14 CDJ85551.1 - 1.6e-164 548.2 0.4 2e-164 547.9 0.4 1.1 1 0 0 1 1 1 1 5' nucleotidase family Hydrolase PF00702.26 CDJ85551.1 - 0.11 12.8 0.0 0.53 10.5 0.0 2.1 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF2206 PF09971.9 CDJ85552.1 - 0.054 12.3 0.4 0.079 11.7 0.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Claudin_2 PF13903.6 CDJ85555.1 - 8e-24 84.5 3.8 9.9e-24 84.2 3.8 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 CDJ85555.1 - 4.3e-06 26.7 5.1 0.00038 20.4 4.8 2.3 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family GRP PF07172.11 CDJ85555.1 - 0.00045 20.9 1.2 0.00045 20.9 1.2 1.8 2 0 0 2 2 2 1 Glycine rich protein family DUF2207 PF09972.9 CDJ85555.1 - 0.0041 16.0 0.6 10 4.8 0.0 2.2 1 1 1 2 2 2 1 Predicted membrane protein (DUF2207) SUR7 PF06687.12 CDJ85555.1 - 0.0041 16.8 1.4 0.0041 16.8 1.4 2.7 2 1 0 3 3 3 1 SUR7/PalI family SCAMP PF04144.13 CDJ85555.1 - 0.051 13.9 7.9 0.099 12.9 7.9 1.4 1 0 0 1 1 1 0 SCAMP family DUF5381 PF17353.2 CDJ85555.1 - 0.1 12.4 3.3 3.2 7.5 0.9 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5381) DUF999 PF06198.11 CDJ85555.1 - 0.12 12.4 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF999) DUF4064 PF13273.6 CDJ85555.1 - 0.24 11.7 8.4 0.86 9.9 1.8 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Tetraspanin PF00335.20 CDJ85555.1 - 0.33 10.6 12.4 2.6 7.7 10.6 2.5 2 1 0 2 2 2 0 Tetraspanin family Trp_oprn_chp PF09534.10 CDJ85555.1 - 0.35 10.6 2.5 0.52 10.1 0.5 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1230 PF06799.11 CDJ85555.1 - 2.3 8.3 6.2 1.2 9.3 1.5 2.1 1 1 1 2 2 2 0 Conserved in the green lineage and diatoms 27 NVEALA PF14055.6 CDJ85555.1 - 4.1 7.5 5.7 4.9 7.2 0.1 3.4 3 1 1 4 4 4 0 NVEALA protein Ank_2 PF12796.7 CDJ85556.1 - 1.6e-42 144.0 2.0 6.5e-15 55.5 0.0 3.7 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ85556.1 - 1.1e-30 105.6 5.6 3.5e-10 40.2 0.0 5.3 2 1 3 5 5 5 5 Ankyrin repeats (many copies) DHHC PF01529.20 CDJ85556.1 - 5.6e-30 104.2 18.8 5.6e-30 104.2 18.8 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_3 PF13606.6 CDJ85556.1 - 2.5e-27 91.9 4.9 0.0013 19.0 0.1 8.2 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 CDJ85556.1 - 3.1e-26 90.6 3.2 0.00033 20.9 0.0 7.4 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 CDJ85556.1 - 1.1e-25 89.3 8.9 2.2e-08 34.2 1.1 5.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Strabismus PF06638.11 CDJ85557.1 - 1.3e-120 403.4 1.0 1.6e-120 403.1 1.0 1.0 1 0 0 1 1 1 1 Strabismus protein DUF1772 PF08592.11 CDJ85557.1 - 1.8 8.9 5.9 34 4.7 4.9 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) CAP PF00188.26 CDJ85558.1 - 8.2e-33 113.9 14.1 1.1e-16 61.9 0.8 2.3 2 0 0 2 2 2 2 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ85558.1 - 0.00011 22.5 3.7 0.17 12.1 0.1 2.8 2 1 0 2 2 2 2 Ancylostoma-associated secreted protein related ATP-synt_F6 PF05511.11 CDJ85558.1 - 0.076 13.4 0.0 8.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 Metallothio_Euk PF12749.7 CDJ85558.1 - 0.13 12.4 19.8 1.4 9.1 5.3 2.9 2 0 0 2 2 2 0 Eukaryotic metallothionein Metallothio_PEC PF02068.16 CDJ85558.1 - 1 9.8 23.9 1.5 9.3 9.9 2.9 2 0 0 2 2 2 0 Plant PEC family metallothionein Metallothio PF00131.20 CDJ85558.1 - 6.1 7.1 25.8 2.8 8.2 6.7 3.5 3 0 0 3 3 3 0 Metallothionein Pyridoxal_deC PF00282.19 CDJ85559.1 - 2.9e-101 338.9 0.0 3.5e-101 338.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 CDJ85559.1 - 4.1e-06 26.2 0.0 6.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II MAP17 PF15807.5 CDJ85559.1 - 0.0017 18.6 0.1 0.0036 17.5 0.1 1.5 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Pro-rich PF15240.6 CDJ85559.1 - 0.0075 16.6 1.1 0.012 15.9 1.1 1.2 1 0 0 1 1 1 1 Proline-rich SepSecS PF05889.13 CDJ85559.1 - 0.012 14.3 0.1 0.018 13.7 0.1 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS ORC5_C PF14630.6 CDJ85559.1 - 0.018 14.6 1.2 0.031 13.8 1.2 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus Shisa PF13908.6 CDJ85559.1 - 0.049 13.9 0.0 0.085 13.1 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator SID-1_RNA_chan PF13965.6 CDJ85559.1 - 0.07 11.5 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CTV_P6 PF06706.11 CDJ85559.1 - 0.075 12.7 0.8 0.16 11.7 0.8 1.4 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein V_ATPase_I PF01496.19 CDJ85559.1 - 0.11 10.4 0.1 0.18 9.7 0.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zip PF02535.22 CDJ85559.1 - 0.16 11.2 0.1 0.24 10.6 0.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 CDJ85559.1 - 0.33 9.7 1.0 0.52 9.0 1.0 1.3 1 0 0 1 1 1 0 Presenilin EphA2_TM PF14575.6 CDJ85559.1 - 4 8.4 5.6 4.2 8.3 3.2 2.3 2 1 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain NPR3 PF03666.13 CDJ85559.1 - 5 5.8 7.1 6.9 5.3 7.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Lectin_C PF00059.21 CDJ85560.1 - 6.4e-17 62.2 0.5 8.3e-17 61.9 0.5 1.1 1 0 0 1 1 1 1 Lectin C-type domain CENP-W PF15510.6 CDJ85561.1 - 0.011 15.9 0.0 0.047 13.9 0.0 1.8 2 0 0 2 2 2 0 CENP-W protein HSP20 PF00011.21 CDJ85562.1 - 4.2e-20 71.8 0.1 4.8e-20 71.6 0.1 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ85562.1 - 0.011 15.3 0.0 0.014 15.0 0.0 1.3 1 1 0 1 1 1 0 HSP20-like domain found in ArsA Exo_endo_phos_2 PF14529.6 CDJ85564.1 - 0.025 14.4 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ85564.1 - 0.061 12.8 0.0 0.087 12.3 0.0 1.3 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Cyt_bd_oxida_II PF02322.15 CDJ85565.1 - 0.013 14.9 0.0 0.014 14.8 0.0 1.0 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II DUF1003 PF06210.11 CDJ85565.1 - 0.12 12.5 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Oxidored_FMN PF00724.20 CDJ85566.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family GST_N_4 PF17172.4 CDJ85567.1 - 6.1e-20 71.8 0.0 1.1e-19 71.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 CDJ85567.1 - 1.7e-16 59.8 0.2 3.7e-16 58.7 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDJ85567.1 - 7.2e-09 35.6 0.1 1.6e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDJ85567.1 - 2.7e-06 27.7 0.0 9.7e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CDJ85567.1 - 1.6e-05 25.1 0.1 3.4e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDJ85567.1 - 0.00056 20.0 0.1 0.001 19.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 CDJ85567.1 - 0.023 14.9 0.0 0.1 12.9 0.0 2.1 2 1 0 2 2 2 0 Glutaredoxin GST_C_6 PF17171.4 CDJ85568.1 - 1.2e-16 60.2 0.1 2.6e-16 59.2 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 CDJ85568.1 - 7e-09 36.3 0.0 1.2e-08 35.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 CDJ85568.1 - 4.5e-08 33.0 0.1 8.9e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDJ85568.1 - 5.3e-06 26.6 0.1 1.1e-05 25.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDJ85568.1 - 0.00055 20.1 0.1 0.00089 19.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDJ85568.1 - 0.056 13.9 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 CDJ85570.1 - 1.4e-19 69.6 0.2 2.3e-19 68.9 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 CDJ85570.1 - 1.2e-10 42.0 0.0 2e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 CDJ85570.1 - 3.6e-10 39.7 0.0 6.7e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDJ85570.1 - 2.5e-06 27.6 0.1 5.6e-06 26.5 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDJ85570.1 - 2.6e-06 27.6 0.0 4.2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDJ85570.1 - 0.018 15.5 0.0 0.045 14.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Erythro_esteras PF05139.14 CDJ85570.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 1 0 1 1 1 0 Erythromycin esterase GST_N_4 PF17172.4 CDJ85571.1 - 2.3e-20 73.2 0.0 3.7e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 CDJ85571.1 - 2.9e-15 55.8 0.1 9e-15 54.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDJ85571.1 - 1.8e-10 40.6 0.0 4.3e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDJ85571.1 - 2.1e-06 28.1 0.1 8.3e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CDJ85571.1 - 6e-06 26.4 0.0 1.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDJ85571.1 - 1e-05 25.6 0.0 2.6e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2621 PF11084.8 CDJ85571.1 - 0.04 13.9 0.3 2.6 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2621) GST_N_4 PF17172.4 CDJ85572.1 - 2.6e-18 66.6 0.0 4.3e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 CDJ85572.1 - 5.3e-17 61.4 0.1 1e-16 60.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDJ85572.1 - 3.1e-08 33.5 0.0 1e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDJ85572.1 - 3.8e-06 27.0 0.0 9.2e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDJ85572.1 - 2.3e-05 24.5 0.0 8.3e-05 22.7 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDJ85572.1 - 0.00024 21.5 0.0 0.00099 19.5 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 CDJ85573.1 - 2.5e-19 69.8 0.0 5e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N_3 PF13417.6 CDJ85573.1 - 8.3e-05 22.9 0.0 0.00029 21.2 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 CDJ85573.1 - 0.0013 18.5 0.1 0.0027 17.4 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDJ85573.1 - 0.031 14.3 0.3 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain RVT_1 PF00078.27 CDJ85574.1 - 5.8e-18 65.2 0.0 8.9e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CDJ85575.1 - 3.2e-19 69.3 0.0 6.2e-19 68.4 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CDJ85576.1 - 2.8e-09 36.8 0.0 3.7e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDJ85577.1 - 0.081 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase RhoGEF PF00621.20 CDJ85579.1 - 2.1e-27 96.5 1.6 2.1e-27 96.5 1.6 1.8 2 0 0 2 2 2 1 RhoGEF domain PH_13 PF16652.5 CDJ85579.1 - 4.1e-09 36.4 0.1 1.2e-08 34.9 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_16 PF17838.1 CDJ85579.1 - 5.1e-07 29.6 0.1 2.9e-06 27.2 0.1 2.1 1 1 0 1 1 1 1 PH domain PH PF00169.29 CDJ85579.1 - 0.00044 20.7 0.0 0.0015 19.0 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_5 PF15405.6 CDJ85579.1 - 0.018 15.2 0.0 0.24 11.5 0.0 2.7 1 1 0 1 1 1 0 Pleckstrin homology domain DUF384 PF04064.13 CDJ85579.1 - 0.093 12.6 1.1 0.23 11.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF384) DUF349 PF03993.12 CDJ85579.1 - 0.36 11.1 3.9 13 6.2 0.2 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) F-box-like PF12937.7 CDJ85580.1 - 0.0044 16.9 1.7 0.014 15.3 1.7 1.9 1 0 0 1 1 1 1 F-box-like Elongin_A PF06881.11 CDJ85580.1 - 0.0046 17.5 0.2 0.0091 16.5 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A CGI-121 PF08617.10 CDJ85581.1 - 3.4e-35 121.6 0.2 4.2e-35 121.3 0.2 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 UPAR_LY6_2 PF16975.5 CDJ85584.1 - 0.0002 21.5 5.5 0.00025 21.2 5.5 1.2 1 0 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 Y_phosphatase PF00102.27 CDJ85585.1 - 1.5e-77 260.3 0.1 2e-77 259.9 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ85585.1 - 1.3e-06 28.3 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDJ85585.1 - 4.7e-06 26.7 0.1 2.8e-05 24.2 0.0 2.1 2 1 0 2 2 2 1 Tyrosine phosphatase family Myotub-related PF06602.14 CDJ85585.1 - 0.0029 16.6 0.0 0.0046 16.0 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain PTPlike_phytase PF14566.6 CDJ85585.1 - 0.0073 16.4 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 CDJ85585.1 - 0.053 13.1 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family ETX_MTX2 PF03318.13 CDJ85586.1 - 8.5e-07 29.0 0.0 9.1e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 DUF4989 PF16379.5 CDJ85586.1 - 0.04 13.2 0.0 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4989) TPR_19 PF14559.6 CDJ85587.1 - 2.4e-11 44.0 9.7 0.0022 18.4 0.0 5.3 3 2 3 6 6 6 5 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ85587.1 - 2.8e-10 40.3 19.2 0.00023 21.3 0.6 6.2 4 3 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CDJ85587.1 - 2.1e-07 30.4 11.1 0.044 13.6 0.3 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ85587.1 - 2.9e-05 23.9 15.3 0.41 10.9 0.0 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ85587.1 - 8.3e-05 22.2 3.0 1.6 8.5 0.2 4.9 4 0 0 4 4 4 2 TPR repeat TPR_8 PF13181.6 CDJ85587.1 - 0.00022 21.2 6.8 3.3 8.2 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ85587.1 - 0.00063 20.0 12.8 0.81 10.0 0.2 6.4 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ85587.1 - 0.0012 19.5 12.8 0.24 12.3 0.1 6.7 7 1 1 8 8 6 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CDJ85587.1 - 0.0053 16.8 6.2 0.11 12.6 0.1 3.3 4 0 0 4 4 4 1 Putative TPR-like repeat TPR_16 PF13432.6 CDJ85587.1 - 0.012 16.2 11.0 0.029 15.0 0.2 4.4 3 2 1 5 5 4 0 Tetratricopeptide repeat PUB_1 PF18486.1 CDJ85587.1 - 0.014 15.3 0.2 0.048 13.5 0.2 1.9 1 0 0 1 1 1 0 PNGase/UBA- or UBX-containing domain TPR_20 PF14561.6 CDJ85587.1 - 0.023 15.0 3.3 18 5.7 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF5560 PF17715.1 CDJ85587.1 - 0.061 12.8 1.8 0.11 11.9 1.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5560) Coatomer_E PF04733.14 CDJ85587.1 - 0.1 12.0 0.2 0.1 12.0 0.2 2.8 4 0 0 4 4 4 0 Coatomer epsilon subunit TPR_21 PF09976.9 CDJ85587.1 - 0.13 12.0 3.4 9.7 5.8 0.0 3.6 4 1 1 5 5 5 0 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 CDJ85587.1 - 0.16 12.2 8.3 5.2 7.3 0.0 3.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ85587.1 - 0.24 12.1 7.5 1e+02 3.9 0.0 6.2 6 1 0 6 6 6 0 Tetratricopeptide repeat Clathrin PF00637.20 CDJ85587.1 - 1.5 8.7 5.6 22 4.9 0.1 3.8 3 1 1 4 4 4 0 Region in Clathrin and VPS YfdX PF10938.8 CDJ85587.1 - 5.7 6.9 6.8 90 3.0 0.2 4.4 4 2 0 5 5 5 0 YfdX protein Galactosyl_T PF01762.21 CDJ85588.1 - 2.6e-74 249.3 0.1 1.1e-36 126.4 0.0 2.2 2 0 0 2 2 2 2 Galactosyltransferase Pou PF00157.17 CDJ85589.1 - 2.3e-30 104.4 0.0 3.9e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 CDJ85589.1 - 1.3e-17 63.4 1.8 3.7e-17 61.9 1.8 1.8 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 CDJ85589.1 - 9.1e-05 22.7 0.1 0.032 14.6 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_3 PF01381.22 CDJ85589.1 - 0.13 12.3 0.1 26 4.9 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix Thioredoxin_12 PF18400.1 CDJ85592.1 - 4.5e-46 157.1 0.0 5.9e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain Collagen PF01391.18 CDJ85593.1 - 1.9e-16 59.5 52.6 6.1e-08 32.3 16.5 3.4 3 0 0 3 3 3 3 Collagen triple helix repeat (20 copies) Endostatin PF06482.11 CDJ85593.1 - 4.2e-06 26.5 0.0 6.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin RT_RNaseH_2 PF17919.1 CDJ85595.1 - 6.2e-10 39.0 0.0 8.8e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ85596.1 - 1.5e-24 86.8 0.0 3.3e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CDJ85596.1 - 0.0063 16.1 0.1 0.018 14.5 0.1 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CDJ85596.1 - 0.025 14.4 0.1 0.093 12.6 0.1 2.0 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase tRNA-synt_2 PF00152.20 CDJ85599.1 - 7.4e-99 330.8 0.0 9.3e-99 330.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CDJ85599.1 - 3.6e-11 42.9 0.0 7.9e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PPE PF00823.19 CDJ85599.1 - 0.07 13.2 0.5 8.8 6.4 0.1 2.2 2 0 0 2 2 2 0 PPE family Col_cuticle_N PF01484.17 CDJ85600.1 - 1.9e-21 75.8 1.0 2.5e-21 75.5 1.0 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ85600.1 - 2.2e-21 75.3 125.5 3.8e-10 39.4 36.8 4.2 3 2 0 3 3 3 3 Collagen triple helix repeat (20 copies) COX14 PF14880.6 CDJ85600.1 - 0.019 14.8 2.3 0.03 14.2 2.3 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Collagen PF01391.18 CDJ85601.1 - 8.8e-24 83.0 116.3 3.1e-10 39.7 36.2 4.0 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ85601.1 - 2.2e-21 75.6 0.7 2.8e-21 75.3 0.7 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain COX14 PF14880.6 CDJ85601.1 - 0.02 14.7 2.3 0.03 14.1 2.3 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Collagen PF01391.18 CDJ85602.1 - 1.2e-22 79.4 113.8 4.2e-10 39.2 31.5 4.1 3 2 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ85602.1 - 8.3e-20 70.6 0.8 1e-19 70.3 0.8 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain COX14 PF14880.6 CDJ85602.1 - 0.65 9.9 4.6 0.99 9.3 4.6 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Pkinase PF00069.25 CDJ85603.1 - 1.4e-25 90.1 0.0 1.8e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ85603.1 - 2.1e-12 46.9 0.0 2.7e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ85603.1 - 0.14 12.1 0.2 3.5 7.5 0.0 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family PAW PF04721.17 CDJ85604.1 - 1.7e-47 161.8 0.1 2.3e-47 161.4 0.1 1.2 1 0 0 1 1 1 1 PNGase C-terminal domain, mannose-binding module PAW Thioredoxin PF00085.20 CDJ85604.1 - 5.3e-25 87.4 0.0 9.9e-25 86.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Transglut_core PF01841.19 CDJ85604.1 - 1.2e-09 38.6 0.1 2.6e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 CDJ85604.1 - 1.6e-09 37.6 0.2 2.9e-09 36.7 0.2 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Thioredoxin_8 PF13905.6 CDJ85604.1 - 9.2e-05 22.7 0.0 0.0049 17.2 0.0 2.5 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 CDJ85604.1 - 0.00011 22.0 0.0 0.00049 19.9 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 CDJ85604.1 - 0.00013 22.4 0.1 0.00067 20.1 0.1 2.3 2 1 0 2 2 2 1 Thioredoxin-like domain TraF PF13728.6 CDJ85604.1 - 0.00089 19.1 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 CDJ85604.1 - 0.02 14.6 0.0 3.4 7.4 0.0 2.4 1 1 1 2 2 2 0 Redoxin TrbC_Ftype PF09673.10 CDJ85604.1 - 0.03 14.4 0.0 0.074 13.1 0.0 1.6 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein OST3_OST6 PF04756.13 CDJ85604.1 - 0.045 13.1 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_14 PF18402.1 CDJ85605.1 - 1.8e-47 162.5 0.0 5.1e-47 161.0 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 CDJ85605.1 - 4.4e-14 52.9 0.1 4.9e-13 49.5 0.0 2.4 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 CDJ85605.1 - 0.17 11.8 0.1 0.84 9.6 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like domain Helitron_like_N PF14214.6 CDJ85606.1 - 3.5e-59 200.2 0.0 3.5e-59 200.2 0.0 2.1 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus zf-C3HC4_2 PF13923.6 CDJ85607.1 - 5.6e-10 38.9 11.5 8.2e-10 38.4 11.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ85607.1 - 1.2e-08 35.2 10.8 1.7e-08 34.7 10.8 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDJ85607.1 - 1.6e-08 34.3 10.1 2e-08 33.9 10.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ85607.1 - 9.6e-08 32.1 9.2 1.5e-07 31.4 9.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 CDJ85607.1 - 9.8e-08 31.7 12.6 1.4e-07 31.2 12.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ85607.1 - 1.5e-07 31.2 11.6 2.1e-07 30.8 11.6 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDJ85607.1 - 1.6e-07 31.2 6.3 3.4e-07 30.2 4.8 2.0 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CDJ85607.1 - 0.00012 21.8 8.0 0.00022 21.0 8.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CDJ85607.1 - 0.00056 19.6 9.3 0.0015 18.3 9.3 1.6 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 CDJ85607.1 - 0.0016 18.6 4.5 0.0021 18.1 4.5 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 TackOD1 PF18551.1 CDJ85607.1 - 0.0051 16.5 3.0 0.0064 16.2 3.0 1.1 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 zf-Nse PF11789.8 CDJ85607.1 - 0.0061 16.4 3.3 0.0083 15.9 3.3 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 CDJ85607.1 - 0.012 15.7 4.4 0.027 14.5 4.3 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CDJ85607.1 - 0.03 14.6 10.8 0.16 12.3 10.8 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 CDJ85607.1 - 0.055 13.3 5.1 0.079 12.8 5.1 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 CDJ85607.1 - 1.5 8.6 10.7 3.8 7.3 10.7 1.8 1 0 0 1 1 1 0 RING-like zinc finger Laps PF10169.9 CDJ85608.1 - 8.6e-09 36.0 17.0 1.2e-07 32.3 17.0 2.0 1 1 0 1 1 1 1 Learning-associated protein DUF2423 PF10338.9 CDJ85608.1 - 0.033 14.4 8.4 0.033 14.4 8.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) Xpo1 PF08389.12 CDJ85609.1 - 2.3e-26 92.6 0.1 4.2e-26 91.8 0.1 1.4 1 0 0 1 1 1 1 Exportin 1-like protein Kunitz_BPTI PF00014.23 CDJ85610.1 - 2.8e-16 59.5 3.0 4.6e-16 58.8 3.0 1.4 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain LSM PF01423.22 CDJ85612.1 - 4.7e-08 32.6 0.0 1.2e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 LSM domain zf-RING_4 PF14570.6 CDJ85613.1 - 6e-20 70.8 13.2 1.2e-19 69.9 13.2 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CDJ85613.1 - 5.4e-06 26.2 7.6 1.3e-05 25.0 7.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 CDJ85613.1 - 8.4e-05 22.3 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.6 CDJ85613.1 - 0.0015 18.4 11.0 0.0039 17.0 11.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ85613.1 - 0.0088 16.4 10.9 0.028 14.7 10.9 1.9 1 0 0 1 1 1 1 Ring finger domain zf-UDP PF14569.6 CDJ85613.1 - 0.35 11.0 3.3 0.97 9.6 3.3 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger DNA_pol_D_N PF18018.1 CDJ85614.1 - 8.4e-27 93.8 0.3 1.1e-26 93.4 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 CDJ85614.1 - 0.00071 19.0 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Sec23_trunk PF04811.15 CDJ85615.1 - 1.8e-77 260.2 0.0 2.7e-77 259.6 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CDJ85615.1 - 8.2e-19 67.3 0.0 1.3e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CDJ85615.1 - 3.1e-15 55.9 3.2 5.6e-15 55.1 3.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 CDJ85615.1 - 1.1e-13 51.7 0.0 1.9e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 CDJ85615.1 - 2.1e-08 33.9 0.0 5.3e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Mob1_phocein PF03637.17 CDJ85616.1 - 1e-67 227.4 0.1 4.1e-67 225.4 0.0 1.9 2 0 0 2 2 2 1 Mob1/phocein family Metallophos PF00149.28 CDJ85616.1 - 5.2e-35 121.8 0.9 8.2e-35 121.2 0.3 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDJ85616.1 - 0.021 15.2 0.4 0.051 14.0 0.4 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain 23S_rRNA_IVP PF05635.11 CDJ85616.1 - 0.082 13.2 0.9 0.93 9.8 1.1 2.3 2 0 0 2 2 2 0 23S rRNA-intervening sequence protein I-set PF07679.16 CDJ85617.1 - 1.8e-12 47.2 0.0 2.4e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ85617.1 - 2e-12 47.5 0.0 5.4e-09 36.5 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 CDJ85617.1 - 5e-09 36.4 0.0 5.3e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 CDJ85617.1 - 6.6e-05 23.0 0.0 0.45 10.7 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 CDJ85617.1 - 0.0029 17.1 0.0 0.99 9.0 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 CDJ85617.1 - 0.071 13.3 0.0 4.6 7.5 0.0 2.7 2 1 1 3 3 3 0 Immunoglobulin V-set domain Meckelin PF09773.9 CDJ85618.1 - 3.2e-210 700.4 1.2 4.4e-210 699.9 1.2 1.2 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) DSPc PF00782.20 CDJ85619.1 - 4.8e-26 91.2 0.0 6.4e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDJ85619.1 - 0.043 13.4 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF1018 PF06252.12 CDJ85622.1 - 0.12 13.3 0.1 0.39 11.7 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) PP2C PF00481.21 CDJ85624.1 - 1.4e-45 155.9 0.0 2e-45 155.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CDJ85624.1 - 0.042 13.5 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein phosphatase 2C HPS6 PF15702.5 CDJ85624.1 - 0.072 11.1 0.0 0.097 10.6 0.0 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 6 protein CybS PF05328.12 CDJ85625.1 - 4.1e-31 107.4 0.1 4.9e-31 107.2 0.1 1.0 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit N6-adenineMlase PF10237.9 CDJ85626.1 - 1.1e-07 31.8 0.0 9.6e-06 25.5 0.0 2.3 1 1 0 1 1 1 1 Probable N6-adenine methyltransferase FLYWCH PF04500.16 CDJ85626.1 - 0.053 13.6 0.8 16 5.7 0.0 2.8 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C3HC4_3 PF13920.6 CDJ85626.1 - 0.21 11.5 9.3 3.1 7.8 0.4 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 CDJ85626.1 - 1.1 9.3 7.6 0.73 9.9 2.0 2.7 2 0 0 2 2 2 0 Double zinc ribbon DHHC PF01529.20 CDJ85626.1 - 1.9 8.6 8.0 0.52 10.4 3.3 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase Toxin_11 PF07473.11 CDJ85627.1 - 0.17 12.0 1.4 0.58 10.3 0.1 2.2 2 0 0 2 2 2 0 Spasmodic peptide gm9a; conotoxin from Conus species Peptidase_C1 PF00112.23 CDJ85628.1 - 3.6e-61 207.0 5.7 4.3e-61 206.8 5.7 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ85628.1 - 0.066 12.0 0.5 0.095 11.4 0.5 1.1 1 0 0 1 1 1 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ85630.1 - 4.7e-59 200.1 7.6 6e-59 199.8 7.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ85630.1 - 0.15 10.8 4.2 0.057 12.2 0.6 1.8 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ85631.1 - 1.9e-62 211.2 7.9 2.3e-62 210.9 7.9 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ85631.1 - 1.1 7.9 6.1 0.18 10.6 1.4 1.9 2 0 0 2 2 2 0 Peptidase C1-like family DUF1768 PF08719.11 CDJ85633.1 - 4.2e-29 101.9 0.0 1.3e-09 38.5 0.0 3.6 3 1 0 3 3 3 3 Domain of unknown function (DUF1768) Rota_NS53 PF00981.17 CDJ85633.1 - 0.045 12.6 0.2 6.9 5.4 0.2 2.2 2 0 0 2 2 2 0 Rotavirus RNA-binding Protein 53 (NS53) Ribosomal_S3_C PF00189.20 CDJ85634.1 - 1.8e-23 82.8 0.9 6.7e-23 81.0 1.3 1.7 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CDJ85634.1 - 8.7e-13 47.9 0.1 1.5e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.5 CDJ85634.1 - 0.098 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus TFIID_20kDa PF03847.13 CDJ85635.1 - 6.6e-18 65.0 1.9 9.5e-18 64.5 1.9 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIIA PF03153.13 CDJ85635.1 - 5.7 6.8 11.6 8.5 6.3 11.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribonuc_L-PSP PF01042.21 CDJ85636.1 - 1.2e-41 141.5 0.1 1.6e-41 141.1 0.1 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP CHIPS PF11434.8 CDJ85636.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS TcpQ PF10671.9 CDJ85639.1 - 0.0036 17.4 0.5 0.025 14.7 0.3 2.1 2 0 0 2 2 2 1 Toxin co-regulated pilus biosynthesis protein Q DUF629 PF04780.12 CDJ85639.1 - 0.013 14.1 0.1 0.02 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) MADF_DNA_bdg PF10545.9 CDJ85640.1 - 1.3e-08 35.0 0.1 1.8e-08 34.6 0.1 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like TAFII28 PF04719.14 CDJ85641.1 - 1.7e-31 108.1 0.0 3.4e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Ras PF00071.22 CDJ85642.1 - 1e-38 132.5 0.0 1.5e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ85642.1 - 4.7e-28 97.8 0.0 8.9e-28 96.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ85642.1 - 7.9e-13 48.2 0.0 1.3e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ85642.1 - 1.7e-07 30.8 0.0 2.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CDJ85642.1 - 0.00032 20.2 0.0 0.00055 19.4 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CDJ85642.1 - 0.0032 16.7 0.1 0.034 13.3 0.1 2.4 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 CDJ85642.1 - 0.0038 17.3 0.0 0.0069 16.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Osteoregulin PF07175.11 CDJ85642.1 - 1 9.5 4.9 0.27 11.4 1.9 1.5 2 0 0 2 2 2 0 Osteoregulin cEGF PF12662.7 CDJ85643.1 - 5.1e-06 26.3 7.0 0.00028 20.7 1.1 7.0 8 0 0 8 8 8 2 Complement Clr-like EGF-like EGF PF00008.27 CDJ85643.1 - 5.5e-06 26.6 3.5 5.5e-06 26.6 3.5 6.9 8 2 0 8 8 8 3 EGF-like domain EGF_CA PF07645.15 CDJ85643.1 - 1.7e-05 24.9 3.2 1.7e-05 24.9 3.2 7.6 5 3 2 7 7 7 2 Calcium-binding EGF domain Cadherin_C_2 PF16492.5 CDJ85643.1 - 0.0034 18.1 0.2 0.34 11.7 0.1 2.6 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal DUF4834 PF16118.5 CDJ85643.1 - 0.014 16.4 0.1 1.4 9.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SEA PF01390.20 CDJ85643.1 - 0.054 13.6 0.3 0.054 13.6 0.3 1.7 2 0 0 2 2 2 0 SEA domain TGF_beta PF00019.20 CDJ85644.1 - 6.2e-30 104.2 0.3 1.3e-29 103.2 0.3 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 CDJ85644.1 - 6.8e-08 32.6 0.0 4.2e-05 23.4 0.1 2.3 1 1 0 2 2 2 2 TGF-beta propeptide Laminin_EGF PF00053.24 CDJ85645.1 - 0.037 14.2 22.2 4.4 7.5 6.0 3.4 1 1 2 3 3 3 0 Laminin EGF domain EGF_2 PF07974.13 CDJ85645.1 - 0.34 11.3 27.1 0.083 13.3 3.2 4.3 4 0 0 4 4 4 0 EGF-like domain DSL PF01414.19 CDJ85645.1 - 0.63 10.4 16.1 1.3e+02 3.0 0.6 3.3 1 1 1 2 2 2 0 Delta serrate ligand Cofilin_ADF PF00241.20 CDJ85646.1 - 7.8e-32 109.6 0.1 9.7e-32 109.3 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Promethin PF16015.5 CDJ85646.1 - 0.0012 18.8 3.0 0.0016 18.3 3.0 1.2 1 0 0 1 1 1 1 Promethin Phage_holin_3_6 PF07332.11 CDJ85646.1 - 0.18 11.9 10.7 0.32 11.0 10.7 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Cofilin_ADF PF00241.20 CDJ85647.1 - 2.2e-27 95.2 0.4 2.7e-27 95.0 0.4 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CLTH PF10607.9 CDJ85648.1 - 9.9e-32 109.9 0.6 1.3e-31 109.4 0.6 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 CDJ85648.1 - 2e-05 24.3 0.0 4.5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 LisH DUF3544 PF12064.8 CDJ85648.1 - 0.14 12.5 6.5 0.29 11.4 6.5 1.5 1 0 0 1 1 1 0 Protein kinase C-binding protein 1 ANAPC4_WD40 PF12894.7 CDJ85649.1 - 0.014 15.7 0.0 0.042 14.2 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain PSD4 PF07631.11 CDJ85649.1 - 0.072 13.6 1.0 0.21 12.2 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1592) Ldl_recept_a PF00057.18 CDJ85651.1 - 0.11 12.8 0.6 0.28 11.5 0.6 1.6 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A SR-25 PF10500.9 CDJ85651.1 - 4 7.0 19.4 1 9.0 5.4 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RCR PF12273.8 CDJ85652.1 - 0.021 15.4 0.0 0.053 14.2 0.0 1.6 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red AA_permease_2 PF13520.6 CDJ85652.1 - 0.054 12.3 0.0 0.059 12.2 0.0 1.3 1 0 0 1 1 1 0 Amino acid permease ShK PF01549.24 CDJ85653.1 - 6.9e-05 23.3 4.0 0.00012 22.6 4.0 1.4 1 0 0 1 1 1 1 ShK domain-like Peptidase_M16_M PF16187.5 CDJ85655.1 - 1.5e-80 270.5 1.4 1.5e-80 270.5 1.4 1.6 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 CDJ85655.1 - 3.3e-44 150.5 0.1 8.9e-43 145.8 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CDJ85655.1 - 2.5e-31 109.1 0.1 5.1e-18 65.7 0.0 2.4 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CDJ85656.1 - 2.9e-36 124.7 0.0 3.8e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) eIF-5_eIF-2B PF01873.17 CDJ85656.1 - 0.084 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Peptidase_M16_M PF16187.5 CDJ85657.1 - 1.4e-24 86.9 0.1 1.8e-24 86.5 0.1 1.1 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 CDJ85657.1 - 1.6e-06 28.2 0.0 3.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain ShK PF01549.24 CDJ85658.1 - 7.7e-06 26.4 6.5 5.9e-05 23.5 6.5 2.3 1 1 0 1 1 1 1 ShK domain-like Motile_Sperm PF00635.26 CDJ85659.1 - 0.032 14.1 0.0 0.04 13.8 0.0 1.1 1 0 0 1 1 1 0 MSP (Major sperm protein) domain Aminotran_1_2 PF00155.21 CDJ85660.1 - 2.2e-68 231.1 0.0 2.6e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CDJ85660.1 - 2.3e-05 23.6 0.0 3.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 CDJ85660.1 - 0.00011 20.9 0.0 0.00016 20.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 CDJ85660.1 - 0.00031 20.1 0.0 0.00039 19.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 CDJ85660.1 - 0.0007 18.4 0.0 0.0072 15.1 0.0 2.0 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.17 CDJ85660.1 - 0.01 15.2 0.1 0.02 14.2 0.1 1.4 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family SWI2_SNF2 PF18766.1 CDJ85660.1 - 0.068 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase SPOR PF05036.13 CDJ85660.1 - 0.076 13.4 0.0 4.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Sporulation related domain HATPase_c_5 PF14501.6 CDJ85660.1 - 0.15 11.9 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 GHKL domain WD40 PF00400.32 CDJ85663.1 - 5.4e-26 90.3 10.0 5.1e-05 24.0 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Ribosomal_S14 PF00253.21 CDJ85663.1 - 8.5e-13 47.9 0.4 8.5e-13 47.9 0.4 2.1 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e ANAPC4_WD40 PF12894.7 CDJ85663.1 - 1.5e-06 28.4 0.3 2.8 8.3 0.0 5.0 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CDJ85663.1 - 0.00049 19.5 0.0 0.0011 18.3 0.0 1.5 1 1 0 1 1 1 1 WD40-like domain PQQ_3 PF13570.6 CDJ85663.1 - 0.012 16.0 0.0 0.84 10.2 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain BSP_II PF05432.11 CDJ85663.1 - 0.69 9.6 6.6 1.6 8.4 6.6 1.6 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TFIIA PF03153.13 CDJ85663.1 - 0.88 9.5 9.4 1.7 8.6 9.4 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Iso_dh PF00180.20 CDJ85664.1 - 1.1e-73 248.4 0.1 1.2e-73 248.2 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Far-17a_AIG1 PF04750.14 CDJ85665.1 - 5.2e-34 117.3 18.5 6.3e-34 117.1 18.5 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Band_7 PF01145.25 CDJ85666.1 - 2.1e-29 102.8 0.1 2.7e-29 102.4 0.1 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CDJ85666.1 - 0.06 13.0 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family DUF2244 PF10003.9 CDJ85667.1 - 3.1 7.4 4.7 13 5.4 0.1 2.1 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Nop16 PF09420.10 CDJ85668.1 - 0.02 14.9 0.2 0.03 14.4 0.2 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 Trypsin PF00089.26 CDJ85668.1 - 0.042 13.6 0.1 0.088 12.6 0.0 1.7 1 1 0 1 1 1 0 Trypsin DUF4915 PF16261.5 CDJ85668.1 - 0.044 13.0 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4915) Trypsin_2 PF13365.6 CDJ85668.1 - 0.14 13.0 0.0 0.23 12.3 0.0 1.5 1 0 0 1 1 1 0 Trypsin-like peptidase domain HLH PF00010.26 CDJ85669.1 - 3.1e-12 46.3 0.7 3.1e-12 46.3 0.7 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain APG6_N PF17675.1 CDJ85669.1 - 0.013 16.0 3.1 0.021 15.4 3.1 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region HOOK PF05622.12 CDJ85669.1 - 0.014 13.6 1.9 0.018 13.2 1.9 1.0 1 0 0 1 1 1 0 HOOK protein Not3 PF04065.15 CDJ85669.1 - 0.1 12.0 0.4 0.17 11.3 0.4 1.2 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Sipho_Gp157 PF05565.11 CDJ85669.1 - 0.15 12.1 1.3 0.25 11.3 1.3 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 Involucrin_N PF10583.9 CDJ85669.1 - 0.23 12.1 5.3 0.55 10.9 3.4 2.5 2 0 0 2 2 2 0 Involucrin of squamous epithelia N-terminus DivIC PF04977.15 CDJ85669.1 - 0.32 10.8 2.8 0.59 9.9 2.8 1.4 1 0 0 1 1 1 0 Septum formation initiator DHR10 PF18595.1 CDJ85669.1 - 0.66 10.0 9.6 0.26 11.3 6.4 1.8 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain LIM_bind PF01803.16 CDJ85670.1 - 6.9e-22 78.2 21.7 2.9e-17 63.0 3.3 3.1 2 1 0 3 3 3 2 LIM-domain binding protein LID PF17916.1 CDJ85670.1 - 3.6e-19 68.1 7.0 3.6e-19 68.1 7.0 2.1 2 0 0 2 2 2 1 LIM interaction domain (LID) GAGA_bind PF06217.12 CDJ85670.1 - 0.0064 16.8 3.0 0.0064 16.8 3.0 1.7 2 0 0 2 2 2 1 GAGA binding protein-like family TF_AP-2 PF03299.14 CDJ85671.1 - 7.5e-69 231.7 0.0 1e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 Transcription factor AP-2 7tm_1 PF00001.21 CDJ85672.1 - 5.3e-05 22.7 13.3 0.00012 21.5 13.3 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4231 PF14015.6 CDJ85672.1 - 1.9 9.0 3.5 11 6.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF5472 PF17566.2 CDJ85674.1 - 0.009 16.0 0.2 0.017 15.1 0.2 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5472) LYRIC PF15686.5 CDJ85674.1 - 0.051 13.1 0.1 0.059 12.9 0.1 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family FixP_N PF14715.6 CDJ85674.1 - 0.29 10.9 1.3 0.42 10.4 1.3 1.2 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP MAP17 PF15807.5 CDJ85674.1 - 0.99 9.7 2.7 1.5 9.0 2.7 1.4 1 1 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 YIF1 PF03878.15 CDJ85676.1 - 1.9e-36 125.8 0.1 2.6e-36 125.4 0.1 1.1 1 0 0 1 1 1 1 YIF1 XRCC4 PF06632.12 CDJ85677.1 - 0.012 14.5 0.8 0.012 14.5 0.8 1.8 1 1 1 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 eIF3g PF12353.8 CDJ85677.1 - 0.14 12.6 0.2 0.14 12.6 0.2 2.5 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G YbaB_DNA_bd PF02575.16 CDJ85678.1 - 0.0066 16.7 1.0 0.01 16.0 0.7 1.5 1 1 0 1 1 1 1 YbaB/EbfC DNA-binding family Tho2 PF11262.8 CDJ85678.1 - 0.029 13.6 0.7 0.036 13.3 0.7 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 baeRF_family3 PF18845.1 CDJ85678.1 - 0.077 13.3 0.3 0.1 12.8 0.3 1.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 Exo_endo_phos_2 PF14529.6 CDJ85679.1 - 0.0027 17.5 0.0 0.0054 16.6 0.0 1.5 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ85679.1 - 0.022 14.3 0.0 0.046 13.2 0.0 1.5 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family PGK PF00162.19 CDJ85680.1 - 1e-16 60.9 0.3 1.2e-16 60.7 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase zf-RING_5 PF14634.6 CDJ85681.1 - 8.4e-06 25.7 2.9 8.4e-06 25.7 2.9 2.8 2 1 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDJ85681.1 - 6.3e-05 22.8 3.2 6.3e-05 22.8 3.2 3.0 2 2 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CDJ85681.1 - 0.00095 19.0 1.4 0.00095 19.0 1.4 2.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ85681.1 - 0.0014 19.0 1.6 0.0014 19.0 1.6 2.6 2 1 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CDJ85681.1 - 0.002 18.1 1.1 0.002 18.1 1.1 2.4 2 1 0 2 2 2 1 RING-type zinc-finger Rsm1 PF08600.10 CDJ85681.1 - 0.004 17.3 0.3 0.004 17.3 0.3 2.3 1 1 1 2 2 2 1 Rsm1-like Bromodomain PF00439.25 CDJ85682.1 - 4e-17 62.1 0.0 1.1e-16 60.7 0.0 1.8 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 CDJ85682.1 - 6.6e-05 22.7 8.2 0.0002 21.1 8.2 1.9 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 CDJ85682.1 - 0.021 14.7 4.8 0.083 12.8 4.8 2.0 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rubredoxin PF00301.20 CDJ85682.1 - 0.043 13.9 1.5 0.15 12.1 1.5 1.9 1 0 0 1 1 1 0 Rubredoxin MFS_1 PF07690.16 CDJ85683.1 - 1.4e-27 96.6 26.8 1.8e-17 63.4 5.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CDJ85683.1 - 1.7e-06 27.6 16.5 1.1e-05 24.9 6.4 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF2788 PF10981.8 CDJ85683.1 - 0.018 15.0 0.9 0.09 12.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2788) HTH_23 PF13384.6 CDJ85684.1 - 4.2e-08 32.8 0.0 4.2e-07 29.6 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.6 CDJ85684.1 - 1.1e-07 31.5 0.7 2.7e-05 23.8 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 CDJ85684.1 - 4.1e-07 29.9 0.2 1.5e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_7 PF02796.15 CDJ85684.1 - 7.4e-07 29.1 0.0 4e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 CDJ85684.1 - 4e-05 24.1 1.2 4e-05 24.1 1.2 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 CDJ85684.1 - 0.0002 21.4 2.0 0.0021 18.2 0.1 2.8 3 1 0 3 3 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 CDJ85684.1 - 0.00036 19.9 0.0 0.0084 15.5 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.6 CDJ85684.1 - 0.00098 18.6 0.0 0.18 11.4 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 CDJ85684.1 - 0.001 18.5 0.0 0.0059 16.1 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_AsnC-type PF13404.6 CDJ85684.1 - 0.0043 16.8 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain CENP-B_N PF04218.13 CDJ85684.1 - 0.0051 16.4 0.1 0.018 14.7 0.0 1.9 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_psq PF05225.16 CDJ85684.1 - 0.011 15.5 0.1 0.14 11.9 0.0 2.4 2 0 0 2 2 2 0 helix-turn-helix, Psq domain HTH_IclR PF09339.10 CDJ85684.1 - 0.02 14.7 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain Sigma70_r4_2 PF08281.12 CDJ85684.1 - 0.02 14.5 0.1 0.39 10.4 0.0 2.8 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_50 PF18024.1 CDJ85684.1 - 0.022 14.3 0.1 0.19 11.4 0.0 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain MarR_2 PF12802.7 CDJ85684.1 - 0.024 14.5 0.1 0.43 10.5 0.0 2.3 2 0 0 2 2 2 0 MarR family HTH_Tnp_4 PF13613.6 CDJ85684.1 - 0.062 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease DDE_3 PF13358.6 CDJ85684.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease Filament PF00038.21 CDJ85686.1 - 4.9e-31 108.5 52.1 3.2e-30 105.8 52.1 1.9 1 1 0 1 1 1 1 Intermediate filament protein Myosin_tail_1 PF01576.19 CDJ85686.1 - 0.00027 18.9 35.6 0.00027 18.9 35.6 2.6 1 1 1 2 2 2 1 Myosin tail MscS_porin PF12795.7 CDJ85686.1 - 0.00062 19.4 2.6 0.00062 19.4 2.6 3.1 1 1 1 2 2 1 1 Mechanosensitive ion channel porin domain CCDC92 PF14916.6 CDJ85686.1 - 0.0021 17.8 0.8 0.09 12.6 0.4 3.0 2 0 0 2 2 2 1 Coiled-coil domain of unknown function HTH_Tnp_IS630 PF01710.16 CDJ85686.1 - 0.0069 16.4 7.9 0.065 13.3 0.1 3.6 2 1 0 3 3 3 1 Transposase CENP-F_leu_zip PF10473.9 CDJ85686.1 - 0.0084 16.1 9.8 0.0084 16.1 9.8 4.7 1 1 2 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Apolipoprotein PF01442.18 CDJ85686.1 - 0.049 13.5 49.1 0.88 9.4 31.3 2.7 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DUF4200 PF13863.6 CDJ85686.1 - 0.084 13.3 42.2 0.31 11.4 2.2 4.8 1 1 2 4 4 4 0 Domain of unknown function (DUF4200) FlxA PF14282.6 CDJ85686.1 - 0.86 9.6 0.0 0.86 9.6 0.0 5.3 2 1 3 5 5 5 0 FlxA-like protein Fib_alpha PF08702.10 CDJ85686.1 - 1.6 8.9 21.7 0.23 11.6 0.8 3.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 CDJ85686.1 - 3.3 8.3 54.3 13 6.4 2.1 4.8 1 1 4 5 5 5 0 Apg6 coiled-coil region FAM184 PF15665.5 CDJ85686.1 - 5.7 6.7 44.4 13 5.5 20.6 3.1 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B KASH_CCD PF14662.6 CDJ85686.1 - 9.7 6.0 44.0 2.2 8.0 9.2 4.1 1 1 3 4 4 4 0 Coiled-coil region of CCDC155 or KASH Filament PF00038.21 CDJ85687.1 - 3.9e-21 75.9 33.6 5.1e-21 75.6 33.6 1.1 1 0 0 1 1 1 1 Intermediate filament protein CENP-F_leu_zip PF10473.9 CDJ85687.1 - 0.00028 20.9 10.4 0.00028 20.9 10.4 3.4 1 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MscS_porin PF12795.7 CDJ85687.1 - 0.0011 18.6 2.6 0.0011 18.6 2.6 3.1 2 1 0 2 2 2 1 Mechanosensitive ion channel porin domain Myosin_tail_1 PF01576.19 CDJ85687.1 - 0.0028 15.5 37.7 0.012 13.4 31.6 2.7 1 1 1 2 2 2 1 Myosin tail CCDC92 PF14916.6 CDJ85687.1 - 0.0037 17.0 3.2 0.051 13.3 0.2 3.4 3 0 0 3 3 3 1 Coiled-coil domain of unknown function HOOK PF05622.12 CDJ85687.1 - 0.02 13.1 29.8 0.0079 14.4 8.3 2.6 1 1 2 3 3 3 0 HOOK protein DUF2353 PF09789.9 CDJ85687.1 - 0.021 14.2 31.9 0.19 11.1 3.8 3.1 1 1 2 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) TPR_MLP1_2 PF07926.12 CDJ85687.1 - 0.024 14.7 34.1 0.26 11.3 15.5 3.7 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein KASH_CCD PF14662.6 CDJ85687.1 - 0.045 13.6 29.0 0.43 10.4 4.8 3.1 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF3450 PF11932.8 CDJ85687.1 - 0.05 12.9 22.7 0.019 14.3 2.1 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) EzrA PF06160.12 CDJ85687.1 - 0.075 11.2 20.2 0.069 11.3 1.6 2.7 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Arm-DNA-bind_1 PF09003.10 CDJ85687.1 - 0.1 12.8 0.1 0.28 11.3 0.1 1.7 1 0 0 1 1 1 0 Bacteriophage lambda integrase, Arm DNA-binding domain FlaC_arch PF05377.11 CDJ85687.1 - 0.12 12.8 9.6 2.4 8.6 0.4 4.7 4 2 1 5 5 5 0 Flagella accessory protein C (FlaC) IMS PF00817.20 CDJ85687.1 - 0.15 12.1 3.5 0.29 11.1 3.3 1.8 1 1 0 1 1 1 0 impB/mucB/samB family DUF4200 PF13863.6 CDJ85687.1 - 0.29 11.5 32.7 0.081 13.3 8.7 4.1 1 1 2 4 4 4 0 Domain of unknown function (DUF4200) DUF2452 PF10504.9 CDJ85687.1 - 0.39 10.2 6.8 0.26 10.8 2.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2452) DUF3410 PF11890.8 CDJ85687.1 - 0.45 10.3 7.2 3.8 7.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3410) PspA_IM30 PF04012.12 CDJ85687.1 - 0.46 10.0 37.2 0.038 13.6 15.4 2.3 1 1 1 2 2 2 0 PspA/IM30 family Spc7 PF08317.11 CDJ85687.1 - 0.77 8.6 32.7 0.12 11.3 11.2 2.7 1 1 2 3 3 3 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 CDJ85687.1 - 0.95 10.1 30.3 0.22 12.2 0.5 4.5 1 1 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Lzipper-MIP1 PF14389.6 CDJ85687.1 - 0.97 9.8 14.3 0.18 12.2 6.2 3.6 2 2 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Fib_alpha PF08702.10 CDJ85687.1 - 1 9.5 16.3 1 9.5 0.7 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF489 PF04356.12 CDJ85687.1 - 1.5 8.8 10.5 1.1 9.3 0.4 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF489) TetR_C_13 PF16925.5 CDJ85687.1 - 1.9 8.5 5.0 7.2 6.6 0.2 3.5 1 1 3 4 4 4 0 Tetracyclin repressor-like, C-terminal domain DUF1664 PF07889.12 CDJ85687.1 - 1.9 8.5 13.9 1 9.4 2.2 3.6 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) ZapB PF06005.12 CDJ85687.1 - 2.3 8.7 27.4 1.5 9.3 4.6 4.9 1 1 3 4 4 4 0 Cell division protein ZapB APG6_N PF17675.1 CDJ85687.1 - 3.1 8.3 38.7 4.1 7.9 7.2 3.8 1 1 1 2 2 2 0 Apg6 coiled-coil region UPF0242 PF06785.11 CDJ85687.1 - 3.7 7.6 27.7 1.3 9.1 4.5 2.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FlxA PF14282.6 CDJ85687.1 - 5.1 7.1 13.7 16 5.5 0.0 4.2 2 1 2 4 4 3 0 FlxA-like protein XhlA PF10779.9 CDJ85687.1 - 5.8 7.2 20.9 0.38 11.0 0.2 5.1 3 3 2 5 5 5 0 Haemolysin XhlA Prominin PF05478.11 CDJ85687.1 - 8.9 4.1 16.0 0.86 7.5 3.2 2.1 1 1 1 2 2 2 0 Prominin FAM184 PF15665.5 CDJ85687.1 - 9.3 6.0 32.6 19 4.9 0.3 2.7 1 1 0 2 2 2 0 Family with sequence similarity 184, A and B Gelsolin PF00626.22 CDJ85688.1 - 9.7e-07 28.6 0.0 1.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Gelsolin repeat Neur_chan_LBD PF02931.23 CDJ85689.1 - 3.3e-44 150.9 2.7 4.6e-44 150.4 2.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ85689.1 - 2.3e-24 86.8 0.6 1.5e-20 74.3 0.2 2.3 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Gelsolin PF00626.22 CDJ85690.1 - 2.1e-28 98.0 0.0 2.6e-17 62.5 0.0 2.3 2 0 0 2 2 2 2 Gelsolin repeat LBP_BPI_CETP_C PF02886.17 CDJ85691.1 - 5.3e-16 58.8 0.4 9.6e-16 57.9 0.4 1.4 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 CDJ85691.1 - 0.002 17.7 0.0 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain Hydrolase_4 PF12146.8 CDJ85693.1 - 2.2e-18 66.4 0.0 4.5e-12 45.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ85693.1 - 3.3e-16 59.7 0.1 9.3e-11 41.8 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CDJ85693.1 - 1.6e-07 31.1 0.0 3.6e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 CDJ85693.1 - 3.7e-07 30.2 0.0 6.8e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 CDJ85693.1 - 5.5e-06 27.1 0.1 0.00081 20.1 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 CDJ85693.1 - 1.5e-05 24.7 0.0 3.4e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 CDJ85693.1 - 5.1e-05 23.0 0.0 0.022 14.3 0.0 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 CDJ85693.1 - 5.8e-05 22.8 0.0 8.6e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) LIP PF03583.14 CDJ85693.1 - 0.00077 18.9 0.1 0.025 13.9 0.1 2.1 2 0 0 2 2 2 1 Secretory lipase DUF818 PF05677.12 CDJ85693.1 - 0.0019 17.2 0.0 0.0031 16.5 0.0 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) BAAT_C PF08840.11 CDJ85693.1 - 0.0051 16.8 0.0 0.88 9.5 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.10 CDJ85693.1 - 0.0054 16.8 0.0 0.0099 16.0 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_5 PF12695.7 CDJ85693.1 - 0.0065 16.3 0.0 0.7 9.6 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF1749 PF08538.10 CDJ85693.1 - 0.009 15.1 0.0 0.013 14.6 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) Ser_hydrolase PF06821.13 CDJ85693.1 - 0.021 14.7 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase Cutinase PF01083.22 CDJ85693.1 - 0.044 13.7 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 Cutinase Say1_Mug180 PF10340.9 CDJ85693.1 - 0.13 11.1 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase Thioesterase PF00975.20 CDJ85693.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Na_H_Exchanger PF00999.21 CDJ85694.1 - 5.4e-77 259.1 44.7 7.1e-77 258.8 44.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Thioredox_DsbH PF03190.15 CDJ85695.1 - 4.6e-71 238.0 0.0 6.8e-71 237.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 CDJ85695.1 - 1.5e-10 41.1 0.0 5.1e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CDJ85695.1 - 0.0017 18.8 0.0 0.038 14.4 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin-like domain Pkinase PF00069.25 CDJ85696.1 - 6.1e-64 215.9 0.0 9.1e-64 215.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ85696.1 - 1.6e-29 103.0 0.0 2.8e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ85696.1 - 0.00012 21.5 0.2 0.0018 17.7 0.2 2.3 1 1 0 1 1 1 1 Kinase-like Focal_AT PF03623.13 CDJ85696.1 - 0.031 14.3 0.5 0.054 13.5 0.5 1.3 1 0 0 1 1 1 0 Focal adhesion targeting region APH PF01636.23 CDJ85696.1 - 0.082 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Linker_histone PF00538.19 CDJ85698.1 - 9.4e-27 93.2 0.6 2.6e-26 91.8 0.6 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family RHH_1 PF01402.21 CDJ85698.1 - 0.13 12.2 0.1 1.9 8.6 0.1 2.3 1 1 1 2 2 2 0 Ribbon-helix-helix protein, copG family ELFV_dehydrog_N PF02812.18 CDJ85699.1 - 0.0011 18.8 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Imm5 PF14423.6 CDJ85699.1 - 0.026 14.7 0.0 0.032 14.5 0.0 1.0 1 0 0 1 1 1 0 Immunity protein Imm5 DUF1027 PF06265.11 CDJ85699.1 - 0.044 13.8 0.1 0.063 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) Phage_fiber_2 PF03406.13 CDJ85699.1 - 0.093 12.3 0.1 0.57 9.8 0.0 2.4 3 0 0 3 3 3 0 Phage tail fibre repeat Transposase_1 PF01359.18 CDJ85700.1 - 0.019 14.8 0.1 0.043 13.6 0.1 1.6 1 0 0 1 1 1 0 Transposase (partial DDE domain) TSGP1 PF07771.11 CDJ85700.1 - 0.085 13.0 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Tick salivary peptide group 1 Dimer_Tnp_hAT PF05699.14 CDJ85701.1 - 3.2e-07 30.0 0.1 6.2e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 CDJ85702.1 - 0.00034 20.6 1.9 0.00077 19.4 1.9 1.6 1 0 0 1 1 1 1 BED zinc finger OrsD PF12013.8 CDJ85702.1 - 0.028 14.9 0.1 0.075 13.5 0.1 1.7 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D Pkinase PF00069.25 CDJ85703.1 - 9.2e-45 153.0 0.0 1.2e-44 152.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ85703.1 - 4.8e-24 85.0 0.0 6.2e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ85703.1 - 0.00083 19.4 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CDJ85703.1 - 0.007 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CDJ85703.1 - 0.007 15.2 0.0 1.6 7.4 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase Choline_kinase PF01633.20 CDJ85703.1 - 0.063 12.9 0.0 0.21 11.2 0.1 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Sugar_tr PF00083.24 CDJ85705.1 - 5.3e-35 121.1 16.6 9.1e-35 120.4 16.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ85705.1 - 1.3e-17 63.8 20.9 8.6e-16 57.8 4.5 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 CDJ85705.1 - 2.1e-05 23.3 4.4 2.1e-05 23.3 4.4 2.8 3 0 0 3 3 3 1 MFS/sugar transport protein TRI12 PF06609.13 CDJ85705.1 - 0.00015 20.3 3.7 0.00015 20.3 3.7 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4807 PF16065.5 CDJ85705.1 - 0.063 12.9 0.4 0.13 11.9 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4807) Med9 PF07544.13 CDJ85705.1 - 0.48 10.5 5.4 0.85 9.7 5.4 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Romo1 PF10247.9 CDJ85705.1 - 7.4 7.0 12.3 0.061 13.7 1.2 2.7 2 1 1 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 CAP PF00188.26 CDJ85706.1 - 3.9e-30 105.3 5.9 4e-15 56.8 0.6 2.2 2 0 0 2 2 2 2 Cysteine-rich secretory protein family Prion PF00377.18 CDJ85706.1 - 0.012 15.5 2.8 1.7 8.5 0.2 2.5 2 0 0 2 2 2 0 Prion/Doppel alpha-helical domain ASPRs PF17641.2 CDJ85706.1 - 0.03 14.6 9.2 1 9.6 1.5 3.6 2 2 0 2 2 2 0 Ancylostoma-associated secreted protein related Adhes-Ig_like PF09085.10 CDJ85706.1 - 0.096 12.8 0.0 5.9 7.1 0.0 2.3 2 0 0 2 2 2 0 Adhesion molecule, immunoglobulin-like TrkA_TMD PF18613.1 CDJ85706.1 - 5.9 6.4 6.3 19 4.8 0.3 2.3 2 0 0 2 2 2 0 Tyrosine kinase receptor A trans-membrane domain Ppx-GppA PF02541.16 CDJ85707.1 - 0.17 11.3 0.1 0.26 10.7 0.1 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family DUF1201 PF06716.11 CDJ85710.1 - 0.0071 16.3 7.3 0.12 12.4 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1201) 7TM_GPCR_Srbc PF10316.9 CDJ85710.1 - 0.019 14.5 4.0 0.025 14.1 4.0 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srab PF10292.9 CDJ85710.1 - 0.07 12.0 1.7 0.089 11.7 1.2 1.6 1 1 1 2 2 2 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor CBFD_NFYB_HMF PF00808.23 CDJ85711.1 - 4e-14 52.6 0.1 7.2e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDJ85711.1 - 0.022 15.1 0.4 0.045 14.1 0.1 1.7 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 CENP-W PF15510.6 CDJ85711.1 - 0.085 13.1 0.4 0.39 11.0 0.2 2.0 2 0 0 2 2 2 0 CENP-W protein Dzip-like_N PF13815.6 CDJ85711.1 - 0.13 12.3 1.4 0.3 11.1 1.0 1.7 1 1 1 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal E1_dh PF00676.20 CDJ85712.1 - 4.3e-89 298.4 0.2 1.4e-86 290.2 0.2 2.1 1 1 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.21 CDJ85712.1 - 5.4e-06 25.6 0.3 1e-05 24.7 0.2 1.5 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.6 CDJ85712.1 - 0.00052 19.3 0.0 0.0017 17.6 0.0 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase DUF155 PF02582.14 CDJ85713.1 - 4.1e-32 111.7 0.0 7.8e-32 110.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 E1_DerP2_DerF2 PF02221.15 CDJ85715.1 - 1.5e-14 54.6 0.4 2e-14 54.2 0.4 1.2 1 0 0 1 1 1 1 ML domain FYVE_2 PF02318.16 CDJ85716.1 - 0.79 9.9 2.1 3.6 7.8 0.9 2.2 1 1 1 2 2 2 0 FYVE-type zinc finger 7tm_1 PF00001.21 CDJ85717.1 - 3.4e-14 52.8 29.5 4.6e-14 52.4 29.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1505 PF07403.11 CDJ85717.1 - 0.068 13.4 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1505) Rad50_zn_hook PF04423.14 CDJ85719.1 - 0.13 12.1 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif Helitron_like_N PF14214.6 CDJ85720.1 - 3.2e-05 24.2 0.1 3.2e-05 24.2 0.1 2.3 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus AMOP PF03782.17 CDJ85721.1 - 2.1e-43 147.9 7.0 4.2e-43 146.9 7.0 1.5 1 0 0 1 1 1 1 AMOP domain NIDO PF06119.14 CDJ85721.1 - 1.6e-05 25.8 0.0 6.7e-05 23.8 0.0 2.2 1 0 0 1 1 1 1 Nidogen-like BclA_C PF18573.1 CDJ85721.1 - 0.0095 15.8 0.6 0.022 14.7 0.0 1.9 2 0 0 2 2 2 1 BclA C-terminal domain RRM_1 PF00076.22 CDJ85724.1 - 1.5e-33 114.4 0.0 1.8e-16 59.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 CDJ85724.1 - 7.1e-19 68.7 0.7 2.5e-18 66.9 0.7 2.0 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 CDJ85724.1 - 0.011 15.6 0.0 0.99 9.3 0.0 2.9 3 0 0 3 3 3 0 Occluded RNA-recognition motif RRM_3 PF08777.11 CDJ85724.1 - 0.011 15.7 0.0 0.091 12.8 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif RRM_5 PF13893.6 CDJ85724.1 - 0.031 13.9 0.0 0.083 12.5 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Orn_Arg_deC_N PF02784.16 CDJ85725.1 - 2e-78 263.2 0.0 2.7e-78 262.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 CDJ85725.1 - 6.9e-14 51.9 0.0 7.9e-14 51.7 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Thioredoxin_7 PF13899.6 CDJ85726.1 - 0.0012 18.9 0.1 0.0026 17.9 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like TB2_DP1_HVA22 PF03134.19 CDJ85727.1 - 1.2e-11 44.4 0.8 2.3e-11 43.5 0.8 1.5 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF3177 PF11375.8 CDJ85727.1 - 0.016 15.0 1.0 0.026 14.3 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3177) DUF4006 PF13179.6 CDJ85727.1 - 0.13 12.2 0.7 0.41 10.6 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF4006) DUF1794 PF08768.11 CDJ85728.1 - 8.4e-05 22.6 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) TPR_2 PF07719.17 CDJ85729.1 - 3.9e-12 45.3 5.7 3.2e-06 26.8 0.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ85729.1 - 8.7e-11 41.2 3.5 8.2e-06 25.4 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ85729.1 - 1.2e-07 31.9 8.9 6.2e-05 23.2 1.1 2.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ85729.1 - 2.6e-07 30.3 4.1 0.014 15.6 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ85729.1 - 2.7e-06 27.0 1.1 0.031 14.0 0.3 3.2 2 1 1 3 3 3 2 TPR repeat ANAPC3 PF12895.7 CDJ85729.1 - 6.1e-06 26.4 2.7 6.1e-06 26.4 2.7 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CDJ85729.1 - 1.5e-05 24.6 2.4 0.076 13.1 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ85729.1 - 3.2e-05 23.6 2.2 0.0054 16.6 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ85729.1 - 4.2e-05 23.6 0.8 0.0018 18.5 0.3 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ85729.1 - 5e-05 23.7 1.3 0.23 12.2 0.2 2.9 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ85729.1 - 8.4e-05 23.0 0.3 0.0012 19.3 0.5 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ85729.1 - 0.0014 19.2 2.7 7.5 7.7 0.2 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ85729.1 - 0.0047 17.0 0.1 0.11 12.6 0.1 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat ETF PF01012.21 CDJ85729.1 - 0.015 15.2 1.2 0.019 14.8 0.4 1.5 2 0 0 2 2 2 0 Electron transfer flavoprotein domain FucT_N PF18025.1 CDJ85729.1 - 0.017 15.6 0.1 0.027 14.9 0.0 1.4 1 1 0 1 1 1 0 Alpha-(1,3)-fucosyltransferase FucT N-terminal domain DUF4093 PF13331.6 CDJ85729.1 - 0.033 14.6 0.0 0.076 13.5 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4093) Fis1_TPR_C PF14853.6 CDJ85729.1 - 0.06 13.4 3.2 0.09 12.9 0.1 2.5 2 1 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 CDJ85729.1 - 0.11 13.2 1.7 0.57 10.9 0.1 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat EBP PF05241.12 CDJ85730.1 - 0.027 13.9 0.1 0.041 13.3 0.1 1.3 1 0 0 1 1 1 0 Emopamil binding protein Suppressor_APC PF11414.8 CDJ85730.1 - 0.075 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein PG_binding_2 PF08823.11 CDJ85730.1 - 0.12 12.8 0.0 0.25 11.7 0.0 1.5 1 1 1 2 2 2 0 Putative peptidoglycan binding domain zf-ZPR1 PF03367.13 CDJ85731.1 - 2.3e-86 287.6 0.7 1.5e-54 184.2 0.5 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Molybdop_Fe4S4 PF04879.16 CDJ85731.1 - 0.073 13.1 0.1 0.073 13.1 0.1 2.9 3 0 0 3 3 3 0 Molybdopterin oxidoreductase Fe4S4 domain Zn-ribbon_8 PF09723.10 CDJ85731.1 - 0.17 12.0 2.7 0.54 10.4 2.7 1.9 1 1 0 1 1 1 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 CDJ85731.1 - 0.27 10.7 6.1 3.5 7.2 1.9 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DDE_3 PF13358.6 CDJ85732.1 - 0.002 17.9 0.4 0.0027 17.5 0.4 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4327 PF14217.6 CDJ85732.1 - 0.19 11.9 1.5 0.39 10.9 0.2 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4327) DUF1758 PF05585.12 CDJ85733.1 - 5.7e-08 32.7 0.0 1.4e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 CDJ85733.1 - 0.00027 21.5 0.1 0.0009 19.8 0.1 2.0 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ85733.1 - 0.0012 19.4 0.1 0.009 16.6 0.0 2.4 1 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ85733.1 - 0.012 16.0 0.1 0.36 11.2 0.0 2.7 1 1 2 3 3 3 0 Retroviral aspartyl protease RVP_2 PF08284.11 CDJ85733.1 - 0.013 15.2 0.0 0.41 10.4 0.0 2.3 1 1 0 2 2 2 0 Retroviral aspartyl protease Bcr-Abl_Oligo PF09036.10 CDJ85733.1 - 0.12 12.3 0.1 0.32 11.0 0.1 1.6 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain Acyltransferase PF01553.21 CDJ85734.1 - 2.1e-14 53.3 0.6 9.2e-13 48.0 0.0 2.1 1 1 1 2 2 2 2 Acyltransferase NETI PF14044.6 CDJ85734.1 - 0.11 12.2 0.0 7.6 6.4 0.0 2.8 2 0 0 2 2 2 0 NETI protein Acyltransferase PF01553.21 CDJ85735.1 - 2.7e-28 98.2 0.1 3.7e-28 97.8 0.1 1.1 1 0 0 1 1 1 1 Acyltransferase Lectin_C PF00059.21 CDJ85736.1 - 2.7e-37 127.8 4.6 7e-20 71.8 1.3 2.1 2 0 0 2 2 2 2 Lectin C-type domain zf-HIT PF04438.16 CDJ85736.1 - 6 6.8 6.7 29 4.6 6.7 2.3 1 1 0 1 1 1 0 HIT zinc finger Lectin_C PF00059.21 CDJ85737.1 - 1.8e-36 125.1 9.1 4.2e-19 69.3 0.8 2.1 2 0 0 2 2 2 2 Lectin C-type domain Chordopox_A33R PF05966.12 CDJ85737.1 - 0.005 16.1 0.0 0.013 14.7 0.0 1.7 1 0 0 1 1 1 1 Chordopoxvirus A33R protein Intimin_C PF07979.11 CDJ85737.1 - 0.034 14.6 0.7 14 6.2 0.0 2.7 2 0 0 2 2 2 0 Intimin C-type lectin domain Xlink PF00193.17 CDJ85737.1 - 0.16 12.4 4.5 7.4 7.0 0.0 3.7 3 1 0 3 3 3 0 Extracellular link domain 7TM_GPCR_Str PF10326.9 CDJ85738.1 - 1.7e-15 57.1 8.3 2e-15 56.9 8.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srh PF10318.9 CDJ85738.1 - 1.1e-09 37.8 7.5 1.3e-09 37.6 7.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Srj PF10319.9 CDJ85738.1 - 1.4e-08 34.5 6.7 1.5e-08 34.3 6.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Srd PF10317.9 CDJ85738.1 - 3.4e-08 33.0 7.3 3.7e-08 32.9 7.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Sri PF10327.9 CDJ85738.1 - 1.2e-05 24.7 5.0 1.3e-05 24.5 5.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri RhoGEF PF00621.20 CDJ85739.1 - 1.7e-17 64.2 2.4 3.3e-17 63.3 2.4 1.4 1 0 0 1 1 1 1 RhoGEF domain PDZ_6 PF17820.1 CDJ85742.1 - 1e-06 28.5 0.0 1.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CDJ85742.1 - 4.6e-05 23.7 0.0 7.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ85742.1 - 0.00064 20.0 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Y_phosphatase PF00102.27 CDJ85743.1 - 1.1e-54 185.5 0.0 1.7e-54 184.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF2442 PF10387.9 CDJ85743.1 - 0.076 13.3 0.4 5.9 7.3 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2442) Y_phosphatase3 PF13350.6 CDJ85743.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family LIM PF00412.22 CDJ85745.1 - 1.2e-69 230.4 87.1 1.4e-13 50.9 9.5 6.5 6 1 0 6 6 6 6 LIM domain PET PF06297.14 CDJ85745.1 - 6.3e-22 77.7 0.0 1.3e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 PET Domain Collagen PF01391.18 CDJ85747.1 - 1.7e-26 91.7 110.0 2.4e-10 40.0 40.3 4.0 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ85747.1 - 6.8e-20 70.9 0.6 8.4e-20 70.6 0.6 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain GBP PF02263.19 CDJ85748.1 - 3.1e-67 226.6 0.0 4e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 CDJ85748.1 - 0.00028 20.4 0.1 0.00039 19.9 0.1 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain Col_cuticle_N PF01484.17 CDJ85748.1 - 0.039 14.0 0.5 0.039 14.0 0.5 2.5 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain DUF229 PF02995.17 CDJ85749.1 - 1e-70 238.8 1.9 1e-70 238.8 1.9 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 CDJ85749.1 - 9.6e-05 21.9 0.1 0.1 12.0 0.0 2.2 1 1 1 2 2 2 2 Sulfatase DUF4440 PF14534.6 CDJ85750.1 - 0.00054 20.3 0.0 0.00064 20.1 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) DUF229 PF02995.17 CDJ85751.1 - 2.5e-80 270.5 0.8 3.6e-80 270.0 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 CDJ85751.1 - 0.00067 19.1 0.5 0.0093 15.4 0.0 2.6 2 1 1 3 3 3 1 Sulfatase EF-hand_13 PF17958.1 CDJ85751.1 - 0.031 14.1 0.1 0.084 12.7 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain Shisa PF13908.6 CDJ85752.1 - 0.85 9.8 0.0 0.85 9.8 0.0 2.8 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator Ribonuc_red_lgC PF02867.15 CDJ85753.1 - 3.8e-192 639.5 0.0 4.6e-192 639.2 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CDJ85753.1 - 1e-25 89.5 0.0 3e-25 88.0 0.0 1.9 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CDJ85753.1 - 2.4e-17 63.2 0.1 8.7e-17 61.5 0.1 2.0 1 0 0 1 1 1 1 ATP cone domain TPR_19 PF14559.6 CDJ85754.1 - 3.5e-24 85.1 28.3 0.00014 22.3 0.3 12.3 8 3 4 12 12 12 5 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ85754.1 - 1e-20 74.1 0.1 0.0021 18.7 0.0 9.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ85754.1 - 3.7e-19 67.8 16.5 0.02 15.6 0.1 12.0 10 2 2 12 12 11 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ85754.1 - 1.7e-14 53.8 10.8 0.038 14.2 0.1 9.3 7 3 3 10 10 10 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CDJ85754.1 - 3.6e-13 49.6 18.7 0.04 14.2 0.1 9.5 9 2 2 11 11 11 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ85754.1 - 9.9e-11 40.9 16.1 0.026 14.6 0.0 10.8 12 0 0 12 12 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ85754.1 - 5.1e-10 38.7 2.4 0.00088 19.1 0.0 7.3 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ85754.1 - 1.2e-08 35.0 23.8 1.1 10.0 0.1 11.8 14 0 0 14 14 12 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ85754.1 - 2.4e-08 33.6 14.0 0.012 15.8 0.1 9.2 12 0 0 12 12 8 1 Tetratricopeptide repeat TPR_4 PF07721.14 CDJ85754.1 - 6.1e-08 32.6 2.6 1 10.2 0.0 7.2 7 0 0 7 7 5 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CDJ85754.1 - 6.8e-07 29.0 0.8 0.021 14.5 0.1 4.0 3 1 0 3 3 3 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_21 PF09976.9 CDJ85754.1 - 6.5e-06 26.0 17.7 9.5e-05 22.2 1.0 6.1 5 2 1 6 6 6 1 Tetratricopeptide repeat-like domain NARP1 PF12569.8 CDJ85754.1 - 1.4e-05 24.3 2.2 0.31 9.9 0.0 3.9 3 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 CDJ85754.1 - 2.7e-05 23.5 13.6 0.0034 16.7 0.6 6.1 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ85754.1 - 7.8e-05 22.8 6.0 0.63 10.6 0.0 7.9 9 0 0 9 9 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ85754.1 - 0.00024 20.8 23.0 0.00099 18.8 0.0 9.0 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ85754.1 - 0.0009 18.9 0.9 0.21 11.3 0.0 4.8 5 0 0 5 5 4 1 TPR repeat TPR_5 PF12688.7 CDJ85754.1 - 0.0035 17.6 6.7 1.3 9.3 0.0 5.1 5 2 1 6 6 5 1 Tetratrico peptide repeat TPR_10 PF13374.6 CDJ85754.1 - 0.017 15.0 12.0 0.86 9.6 0.0 7.3 10 0 0 10 10 8 0 Tetratricopeptide repeat FAT PF02259.23 CDJ85754.1 - 0.026 13.7 3.1 0.57 9.3 2.9 3.0 3 1 0 3 3 3 0 FAT domain SNAP PF14938.6 CDJ85754.1 - 0.041 13.3 2.9 1.9 7.8 0.4 3.8 3 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_9 PF13371.6 CDJ85754.1 - 0.045 13.9 3.5 5.8 7.1 0.0 5.0 4 2 1 5 5 5 0 Tetratricopeptide repeat PknG_TPR PF16918.5 CDJ85754.1 - 0.091 11.5 0.3 0.81 8.4 0.0 2.9 4 1 0 4 4 4 0 Protein kinase G tetratricopeptide repeat ChAPs PF09295.10 CDJ85754.1 - 0.17 10.9 1.6 1.6 7.7 0.1 2.7 1 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) LppC PF04348.13 CDJ85754.1 - 0.27 10.0 8.9 0.74 8.5 0.1 3.6 5 0 0 5 5 5 0 LppC putative lipoprotein SHNi-TPR PF10516.9 CDJ85754.1 - 0.63 9.5 2.2 1.6 8.2 0.0 2.8 4 0 0 4 4 3 0 SHNi-TPR WW PF00397.26 CDJ85755.1 - 1.6e-08 34.5 8.9 4.7e-08 33.0 0.4 2.6 2 0 0 2 2 2 1 WW domain PDZ PF00595.24 CDJ85755.1 - 8e-08 32.5 0.0 1.9e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDJ85755.1 - 1.7e-07 31.0 0.2 4.7e-07 29.5 0.2 1.9 1 0 0 1 1 1 1 PDZ domain FERM_M PF00373.18 CDJ85755.1 - 1.9e-06 28.3 0.7 8.7e-06 26.1 0.1 2.3 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.10 CDJ85755.1 - 4.9e-06 26.4 0.0 4.8e-05 23.2 0.0 2.4 2 0 0 2 2 2 1 FERM N-terminal domain FERM_f0 PF16511.5 CDJ85755.1 - 0.00082 19.6 0.0 0.013 15.7 0.0 2.4 2 0 0 2 2 2 1 N-terminal or F0 domain of Talin-head FERM FERM_N_2 PF18038.1 CDJ85755.1 - 0.00093 20.0 0.2 0.013 16.4 0.0 2.9 3 0 0 3 3 3 1 FERM N-terminal domain RA PF00788.23 CDJ85755.1 - 0.0021 18.6 0.0 0.0051 17.4 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PDZ_2 PF13180.6 CDJ85755.1 - 0.029 14.7 0.1 0.091 13.1 0.1 1.8 1 0 0 1 1 1 0 PDZ domain RBD PF02196.15 CDJ85755.1 - 0.089 12.9 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Raf-like Ras-binding domain SH3_17 PF18350.1 CDJ85757.1 - 1.5 8.8 3.3 27 4.8 0.1 3.2 3 0 0 3 3 3 0 Restriction endonuclease SH3 domain ig PF00047.25 CDJ85758.1 - 1e-07 32.0 0.0 1.3e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 CDJ85758.1 - 4e-07 30.5 0.0 5.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CDJ85758.1 - 1.2e-06 28.8 0.0 1.7e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 CDJ85758.1 - 1.2e-06 28.5 0.3 1.8e-06 27.9 0.3 1.4 1 1 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 CDJ85758.1 - 0.0007 19.8 0.0 0.0083 16.3 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_4 PF16680.5 CDJ85758.1 - 0.0022 18.2 0.2 0.087 13.1 0.2 2.3 1 1 0 1 1 1 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 CDJ85758.1 - 0.017 15.5 1.0 1.2 9.5 1.0 2.4 1 1 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain HTH_38 PF13936.6 CDJ85759.1 - 1.6e-07 31.0 0.2 1.6e-07 31.0 0.2 3.1 4 1 0 4 4 4 1 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 CDJ85759.1 - 1.8e-06 27.7 1.0 8.5e-06 25.5 0.0 2.4 2 1 0 2 2 2 1 Tc3 transposase HTH_Tnp_Tc3_2 PF01498.18 CDJ85759.1 - 2.5e-06 27.7 3.3 1e-05 25.7 1.1 2.2 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 CDJ85759.1 - 1.8e-05 25.3 4.8 0.014 16.0 1.5 2.3 1 1 1 2 2 2 2 Homeodomain-like domain HTH_23 PF13384.6 CDJ85759.1 - 0.015 15.1 0.7 0.86 9.5 0.1 2.5 2 0 0 2 2 2 0 Homeodomain-like domain BIR PF00653.21 CDJ85759.1 - 0.088 13.5 0.0 8.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain HTH_24 PF13412.6 CDJ85759.1 - 0.18 11.4 2.9 20 4.9 0.3 3.4 3 1 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_Tnp_ISL3 PF13542.6 CDJ85759.1 - 0.18 11.2 4.1 0.34 10.4 2.5 2.2 2 1 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 V-set PF07686.17 CDJ85760.1 - 8.5e-08 32.4 0.0 1.4e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 CDJ85760.1 - 3.4e-06 27.0 0.0 4.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 CDJ85760.1 - 8.1e-06 25.9 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 CDJ85760.1 - 0.0003 21.3 0.0 0.00056 20.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CDJ85760.1 - 0.0027 18.0 0.0 0.0056 17.0 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain Izumo-Ig PF16706.5 CDJ85760.1 - 0.16 12.0 0.0 0.36 10.9 0.0 1.8 1 1 0 1 1 1 0 Izumo-like Immunoglobulin domain Ank_2 PF12796.7 CDJ85761.1 - 1.8e-52 175.9 2.1 1.7e-17 63.8 0.0 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ85761.1 - 2.2e-38 130.1 4.9 3.9e-12 46.4 0.4 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ85761.1 - 3.4e-28 94.6 0.4 2.1e-06 27.6 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 CDJ85761.1 - 2e-25 88.1 0.5 1.1e-06 28.8 0.2 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 CDJ85761.1 - 8.4e-25 86.5 3.0 1.2e-08 35.0 0.1 4.9 1 1 4 5 5 5 4 Ankyrin repeats (many copies) COX17 PF05051.13 CDJ85761.1 - 9.3e-20 70.7 8.5 9.3e-20 70.7 8.5 2.0 2 0 0 2 2 1 1 Cytochrome C oxidase copper chaperone (COX17) Sec20 PF03908.13 CDJ85761.1 - 1.8e-19 69.4 1.0 1.8e-19 69.4 1.0 2.7 3 1 0 3 3 3 1 Sec20 DUF948 PF06103.11 CDJ85761.1 - 0.0038 17.4 3.4 0.032 14.5 0.0 3.2 3 1 0 3 3 3 1 Bacterial protein of unknown function (DUF948) Synaptobrevin PF00957.21 CDJ85761.1 - 0.0098 15.7 3.6 0.029 14.2 0.1 2.9 2 1 0 2 2 2 1 Synaptobrevin T2SSM PF04612.12 CDJ85761.1 - 0.083 12.9 2.8 0.76 9.8 0.0 3.0 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein M CRR7 PF12095.8 CDJ85761.1 - 1.3 9.5 5.3 4.9 7.7 0.0 3.5 3 1 0 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 Syntaxin_2 PF14523.6 CDJ85761.1 - 2.6 8.5 13.9 3 8.3 2.5 3.4 2 1 2 4 4 4 0 Syntaxin-like protein UQ_con PF00179.26 CDJ85762.1 - 1.8e-44 150.8 0.0 2.4e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ85762.1 - 1e-05 25.3 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CDJ85762.1 - 0.00033 20.9 0.0 0.00049 20.4 0.0 1.3 1 0 0 1 1 1 1 RWD domain UBA PF00627.31 CDJ85762.1 - 0.0058 16.5 0.6 0.0099 15.8 0.0 1.7 2 0 0 2 2 2 1 UBA/TS-N domain UFC1 PF08694.11 CDJ85762.1 - 0.039 13.6 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 UBA_4 PF14555.6 CDJ85762.1 - 0.16 11.8 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 UBA-like domain HLH PF00010.26 CDJ85763.1 - 2e-13 50.0 0.0 3.9e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain BLOC1_2 PF10046.9 CDJ85763.1 - 0.029 14.7 0.2 0.056 13.8 0.2 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.11 CDJ85763.1 - 0.034 14.4 2.5 0.043 14.0 2.5 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4094 PF13334.6 CDJ85763.1 - 0.064 13.7 0.7 0.18 12.2 0.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) SCVP PF17619.2 CDJ85764.1 - 5.7e-18 65.6 0.0 6.4e-18 65.4 0.0 1.0 1 0 0 1 1 1 1 Secreted clade V proteins SCVP PF17619.2 CDJ85765.1 - 3.9e-18 66.1 0.1 5.3e-18 65.7 0.1 1.2 1 0 0 1 1 1 1 Secreted clade V proteins Lamprin PF06403.11 CDJ85765.1 - 0.019 14.9 14.6 0.031 14.3 14.6 1.4 1 0 0 1 1 1 0 Lamprin Keratin_2_head PF16208.5 CDJ85765.1 - 0.31 11.2 24.8 0.48 10.6 24.8 1.3 1 0 0 1 1 1 0 Keratin type II head SCVP PF17619.2 CDJ85766.1 - 2.1e-06 28.5 0.0 3.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Secreted clade V proteins ANAPC8 PF04049.13 CDJ85767.1 - 0.071 13.2 1.5 0.16 12.0 0.2 1.9 2 0 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 XendoU PF09412.10 CDJ85768.1 - 6.7e-79 264.8 0.0 7.9e-79 264.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU EndoU_bacteria PF14436.6 CDJ85768.1 - 0.0045 17.3 0.1 0.012 15.9 0.1 1.7 1 0 0 1 1 1 1 Bacterial EndoU nuclease XendoU PF09412.10 CDJ85769.1 - 5e-64 216.1 0.0 1.9e-38 132.2 0.0 2.0 1 1 1 2 2 2 2 Endoribonuclease XendoU MFS_1 PF07690.16 CDJ85771.1 - 1.6e-69 234.5 35.3 1.6e-69 234.5 35.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3701 PF12482.8 CDJ85772.1 - 0.092 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Phage integrase protein Peptidase_M1 PF01433.20 CDJ85773.1 - 5.3e-07 29.4 0.5 2e-06 27.6 0.5 1.8 1 1 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CDJ85773.1 - 0.011 16.0 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 Peptidase M1 N-terminal domain Prophage_tail PF06605.11 CDJ85773.1 - 0.047 12.9 0.0 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 Prophage endopeptidase tail Collagen PF01391.18 CDJ85774.1 - 5.6e-26 90.1 85.6 1.8e-09 37.2 27.0 4.2 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ85774.1 - 2.8e-11 43.3 0.0 3.9e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain DUF3774 PF12609.8 CDJ85775.1 - 0.21 12.6 3.0 0.33 12.0 3.0 1.3 1 0 0 1 1 1 0 Wound-induced protein LMBR1 PF04791.16 CDJ85776.1 - 1.4e-55 189.2 24.1 4.4e-55 187.5 24.1 1.7 1 1 0 1 1 1 1 LMBR1-like membrane protein Colicin_im PF03857.13 CDJ85776.1 - 0.68 9.9 10.0 0.58 10.1 5.6 2.4 2 0 0 2 2 2 0 Colicin immunity protein Orf78 PF06024.12 CDJ85776.1 - 1.5 9.1 0.0 1.5 9.1 0.0 3.3 3 1 1 4 4 4 0 Orf78 (ac78) Astacin PF01400.24 CDJ85777.1 - 9.7e-51 172.1 1.1 1.4e-50 171.5 1.1 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) ubiquitin PF00240.23 CDJ85778.1 - 2e-08 33.9 1.0 6.7e-08 32.2 0.1 2.5 2 0 0 2 2 2 1 Ubiquitin family zf-AN1 PF01428.16 CDJ85778.1 - 0.0002 21.4 9.4 0.0004 20.5 9.4 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Ubiquitin_4 PF18036.1 CDJ85778.1 - 0.0032 17.5 1.3 0.77 9.8 0.0 3.4 2 1 1 3 3 3 1 Ubiquitin-like domain Rad60-SLD PF11976.8 CDJ85778.1 - 0.012 15.4 0.5 0.035 13.9 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 CDJ85778.1 - 0.046 13.6 0.3 0.22 11.5 0.0 2.2 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain zf-RING_5 PF14634.6 CDJ85778.1 - 1.4 9.0 8.1 3 7.9 8.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain LAX PF15681.5 CDJ85779.1 - 0.097 11.5 4.5 0.11 11.3 4.5 1.2 1 0 0 1 1 1 0 Lymphocyte activation family X zf-AN1 PF01428.16 CDJ85780.1 - 2.4e-05 24.4 12.8 4.3e-05 23.6 12.8 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger SR-25 PF10500.9 CDJ85780.1 - 0.29 10.7 7.7 0.49 10.0 7.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CAP PF00188.26 CDJ85782.1 - 6.2e-18 65.9 5.1 8.9e-18 65.3 5.1 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ85782.1 - 0.035 14.4 3.2 0.41 10.9 3.2 2.4 1 1 0 1 1 1 0 Ancylostoma-associated secreted protein related CAP PF00188.26 CDJ85783.1 - 1.1e-09 39.2 0.8 1.8e-09 38.5 0.8 1.4 1 1 0 1 1 1 1 Cysteine-rich secretory protein family SET PF00856.28 CDJ85784.1 - 2e-28 99.9 0.7 5.6e-28 98.4 0.1 2.1 2 0 0 2 2 2 1 SET domain Pre-SET PF05033.16 CDJ85784.1 - 2e-16 60.6 8.6 2e-16 60.6 8.6 2.6 3 0 0 3 3 3 1 Pre-SET motif MBD PF01429.19 CDJ85784.1 - 3.9e-08 32.9 0.0 1e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Methyl-CpG binding domain TUDOR_5 PF18359.1 CDJ85784.1 - 2.3e-07 30.4 0.0 5.4e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 Dehydrin PF00257.19 CDJ85784.1 - 0.0099 16.4 4.3 0.019 15.5 4.3 1.4 1 0 0 1 1 1 1 Dehydrin SR-25 PF10500.9 CDJ85784.1 - 0.036 13.7 10.8 0.03 13.9 8.5 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Hydantoinase_B PF02538.14 CDJ85784.1 - 0.099 11.0 1.5 0.15 10.4 0.3 1.8 3 0 0 3 3 3 0 Hydantoinase B/oxoprolinase CCDC106 PF15794.5 CDJ85784.1 - 1.1 8.9 6.3 2.2 7.9 6.3 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CDC45 PF02724.14 CDJ85784.1 - 2.1 6.5 9.7 3.4 5.8 9.7 1.2 1 0 0 1 1 1 0 CDC45-like protein XRCC4 PF06632.12 CDJ85784.1 - 2.6 6.8 7.9 0.41 9.4 4.1 1.5 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 RNA_polI_A34 PF08208.11 CDJ85784.1 - 4.1 7.4 10.9 7.1 6.7 10.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DNA_topoisoIV PF00521.20 CDJ85785.1 - 1.4e-100 337.2 0.2 3.2e-100 336.0 0.0 1.6 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CDJ85785.1 - 1.6e-38 131.9 2.8 1.6e-38 131.9 2.8 1.9 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CDJ85785.1 - 2.7e-18 66.1 0.0 6.1e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CDJ85785.1 - 2.2e-12 47.5 0.0 5.2e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CDJ85785.1 - 5.6e-07 29.7 0.0 2.6e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Toprim domain zinc_ribbon_9 PF14369.6 CDJ85786.1 - 0.024 14.9 0.9 0.099 12.9 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon zf-C2H2_4 PF13894.6 CDJ85786.1 - 0.04 14.8 0.7 0.04 14.8 0.7 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 CDJ85786.1 - 0.058 13.7 1.0 0.2 11.9 1.0 2.0 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 CDJ85786.1 - 0.076 12.9 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) zf_UBZ PF18439.1 CDJ85786.1 - 0.085 12.5 3.1 0.081 12.5 0.8 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DNA_topoisoIV PF00521.20 CDJ85787.1 - 2.4e-05 23.4 0.5 2.7e-05 23.3 0.5 1.0 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A RRM_1 PF00076.22 CDJ85788.1 - 2.8e-12 46.3 0.0 4.2e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ85788.1 - 0.00065 19.3 0.0 0.00099 18.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_fiss_reg PF05308.11 CDJ85788.1 - 0.27 11.3 2.4 0.36 10.9 2.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 CDJ85788.1 - 0.81 9.1 5.1 1.2 8.5 5.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 CDJ85788.1 - 1.1 9.3 5.9 1.7 8.7 5.9 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Integrase_H2C2 PF17921.1 CDJ85789.1 - 2.3e-15 56.4 1.1 6.7e-15 54.9 1.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDJ85789.1 - 4.4e-06 26.9 0.0 1.5e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 CDJ85789.1 - 0.15 11.6 0.0 0.73 9.3 0.0 2.1 2 1 1 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) SH3_9 PF14604.6 CDJ85790.1 - 1.9e-34 117.3 0.9 2.8e-18 65.5 0.1 3.7 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 CDJ85790.1 - 1.7e-31 107.6 0.5 1.1e-14 53.8 0.2 3.4 3 0 0 3 3 3 2 SH3 domain SH3_2 PF07653.17 CDJ85790.1 - 2.8e-26 91.0 1.5 1.1e-15 57.0 0.1 3.3 3 0 0 3 3 3 2 Variant SH3 domain SH2 PF00017.24 CDJ85790.1 - 2.4e-21 75.6 0.0 4.1e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SH3_3 PF08239.11 CDJ85790.1 - 0.00036 20.8 2.3 0.018 15.3 1.7 3.2 4 0 0 4 4 4 1 Bacterial SH3 domain hSH3 PF14603.6 CDJ85790.1 - 0.0009 19.6 0.0 1 9.8 0.0 2.5 2 0 0 2 2 2 2 Helically-extended SH3 domain SH3_10 PF17902.1 CDJ85790.1 - 0.013 15.6 0.1 8.3 6.6 0.0 2.6 2 0 0 2 2 2 0 SH3 domain SH2_2 PF14633.6 CDJ85790.1 - 0.039 13.4 0.0 0.19 11.1 0.0 1.9 1 1 0 1 1 1 0 SH2 domain zf-HC5HC2H_2 PF13832.6 CDJ85791.1 - 7.5e-33 113.0 11.8 7.5e-33 113.0 11.8 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CDJ85791.1 - 1.6e-21 76.4 7.7 1.6e-21 76.4 7.7 3.9 3 1 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.25 CDJ85791.1 - 2.5e-18 65.9 0.0 6.5e-18 64.6 0.0 1.8 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.6 CDJ85791.1 - 7.2e-16 57.5 5.1 7.2e-16 57.5 5.1 2.9 2 0 0 2 2 2 1 PHD-finger EPL1 PF10513.9 CDJ85791.1 - 1.1e-15 58.4 1.0 1.1e-15 58.4 1.0 1.8 2 0 0 2 2 2 1 Enhancer of polycomb-like PHD PF00628.29 CDJ85791.1 - 4.3e-09 36.1 9.0 4.3e-09 36.1 9.0 3.2 4 0 0 4 4 4 2 PHD-finger C1_1 PF00130.22 CDJ85791.1 - 0.0017 18.2 1.1 0.0017 18.2 1.1 3.2 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.25 CDJ85792.1 - 1.1e-13 51.1 0.1 2e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ85792.1 - 3.3e-06 26.6 0.0 5.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ85792.1 - 8e-06 24.9 0.0 1.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase 7TM_GPCR_Srv PF10323.9 CDJ85793.1 - 1.9e-14 53.7 21.3 2.3e-11 43.6 11.6 2.2 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv Srg PF02118.21 CDJ85793.1 - 6.4e-12 45.7 23.6 2.3e-09 37.3 12.7 2.2 1 1 1 2 2 2 2 Srg family chemoreceptor 7TM_GPCR_Srx PF10328.9 CDJ85793.1 - 2.7e-09 37.0 16.7 3.5e-09 36.7 16.1 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 CDJ85793.1 - 0.00034 20.0 13.3 0.00041 19.8 12.8 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF621 PF04789.15 CDJ85793.1 - 1.4 8.0 25.3 2.1 7.4 11.5 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF621) AAA_11 PF13086.6 CDJ85794.1 - 4.3e-10 39.8 0.0 7.4e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ85794.1 - 3.3e-09 36.7 0.1 0.00024 20.9 0.4 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CDJ85794.1 - 3.9e-05 24.0 0.1 0.00013 22.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 CDJ85794.1 - 0.0035 17.2 0.2 0.23 11.3 0.2 2.3 2 0 0 2 2 2 1 Helicase ResIII PF04851.15 CDJ85794.1 - 0.027 14.5 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 CDJ85794.1 - 0.055 14.0 0.0 15 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 CDJ85794.1 - 0.083 12.7 0.0 2.7 7.7 0.0 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase PhoH PF02562.16 CDJ85794.1 - 0.15 11.5 0.0 11 5.4 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 CDJ85795.1 - 0.013 15.2 2.3 0.013 15.2 0.7 1.7 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 CDJ85795.1 - 0.056 13.4 0.0 0.094 12.7 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 CDJ85795.1 - 0.17 11.6 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Abhydrolase_1 PF00561.20 CDJ85796.1 - 6.6e-05 22.7 0.0 0.00018 21.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ85796.1 - 0.0068 15.7 0.0 0.2 10.9 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydro_lipase PF04083.16 CDJ85797.1 - 1.4e-26 91.8 0.1 2e-26 91.3 0.1 1.2 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 CDJ85797.1 - 0.0075 15.9 0.0 0.0098 15.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold 7tm_1 PF00001.21 CDJ85798.1 - 1e-73 247.9 4.0 1.5e-73 247.3 4.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ85798.1 - 1.5e-10 40.9 11.6 7.7e-08 32.0 5.7 2.4 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 CDJ85798.1 - 8.1e-10 38.8 6.0 8.1e-10 38.8 6.0 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 CDJ85798.1 - 3e-08 33.7 2.5 4.9e-07 29.8 2.9 2.3 2 1 0 2 2 2 1 Olfactory receptor CitMHS PF03600.16 CDJ85798.1 - 0.058 12.6 0.4 0.063 12.5 0.4 1.2 1 0 0 1 1 1 0 Citrate transporter DUF1980 PF09323.10 CDJ85798.1 - 0.063 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Pkinase PF00069.25 CDJ85799.1 - 3.1e-52 177.6 0.0 1.1e-50 172.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain PH_3 PF14593.6 CDJ85799.1 - 3e-41 139.8 0.0 8.1e-41 138.3 0.0 1.8 1 0 0 1 1 1 1 PH domain Pkinase_Tyr PF07714.17 CDJ85799.1 - 1.7e-21 76.7 0.0 3.4e-16 59.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDJ85799.1 - 1.7e-05 24.3 0.0 0.0082 15.5 0.0 2.5 3 0 0 3 3 3 2 Kinase-like PH PF00169.29 CDJ85799.1 - 0.0015 19.0 0.1 0.0052 17.3 0.0 1.9 2 0 0 2 2 1 1 PH domain PH_8 PF15409.6 CDJ85799.1 - 0.0021 18.3 0.0 0.0079 16.4 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain Haspin_kinase PF12330.8 CDJ85799.1 - 0.01 14.8 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain SNRNP27 PF08648.12 CDJ85799.1 - 0.037 14.1 0.5 0.11 12.6 0.5 1.7 1 0 0 1 1 1 0 U4/U6.U5 small nuclear ribonucleoproteins Pkinase_fungal PF17667.1 CDJ85799.1 - 0.044 12.6 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 CDJ85799.1 - 0.086 12.5 1.7 3.1 7.3 0.0 3.4 3 1 1 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 TMEM190 PF15431.6 CDJ85799.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 190 RIO1 PF01163.22 CDJ85799.1 - 0.47 10.0 2.2 0.52 9.9 0.0 2.0 2 0 0 2 2 2 0 RIO1 family DUF5089 PF17002.5 CDJ85800.1 - 5.5e-06 26.4 4.4 6.9e-06 26.1 4.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5089) V-SNARE_C PF12352.8 CDJ85800.1 - 3.1e-05 24.2 2.3 0.0002 21.6 0.1 2.4 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF948 PF06103.11 CDJ85800.1 - 0.0048 17.1 5.5 0.18 12.1 0.7 2.6 2 1 1 3 3 3 2 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 CDJ85800.1 - 0.0077 16.3 4.7 0.2 11.6 0.4 2.3 2 0 0 2 2 2 2 Laminin Domain II DUF1664 PF07889.12 CDJ85800.1 - 0.014 15.5 5.2 0.81 9.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) COG5 PF10392.9 CDJ85800.1 - 0.024 14.8 1.0 0.34 11.1 0.4 2.2 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DASH_Duo1 PF08651.10 CDJ85800.1 - 0.026 14.3 3.1 0.52 10.1 0.1 2.6 2 1 0 2 2 2 0 DASH complex subunit Duo1 mRNA_cap_C PF03919.15 CDJ85800.1 - 0.037 14.7 0.6 0.061 14.0 0.4 1.5 1 1 1 2 2 2 0 mRNA capping enzyme, C-terminal domain Baculo_PEP_C PF04513.12 CDJ85800.1 - 0.048 13.7 5.7 1.5 8.9 0.1 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2205 PF10224.9 CDJ85800.1 - 0.18 11.8 2.4 1 9.4 0.8 2.4 2 0 0 2 2 2 0 Short coiled-coil protein MscS_porin PF12795.7 CDJ85800.1 - 0.21 11.1 4.2 4.3 6.8 0.1 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain SNARE PF05739.19 CDJ85800.1 - 0.26 11.3 8.9 0.84 9.7 0.1 2.9 3 0 0 3 3 3 0 SNARE domain HIP1_clath_bdg PF16515.5 CDJ85800.1 - 0.37 11.4 6.9 0.86 10.3 2.2 2.6 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 LXG PF04740.12 CDJ85800.1 - 2.1 8.0 7.6 15 5.2 7.3 2.1 1 1 0 1 1 1 0 LXG domain of WXG superfamily zf-C3HC4_2 PF13923.6 CDJ85802.1 - 7.5e-11 41.7 8.5 1.2e-10 41.0 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ85802.1 - 3.7e-10 40.0 7.2 6.2e-10 39.2 7.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDJ85802.1 - 1.7e-09 37.3 6.7 2.4e-09 36.9 6.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ85802.1 - 3.6e-08 33.2 8.8 5.5e-08 32.5 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ85802.1 - 3.5e-07 30.1 3.9 7e-07 29.2 2.2 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDJ85802.1 - 5.1e-07 29.6 8.0 7.5e-07 29.0 8.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDJ85802.1 - 1.8e-06 27.7 4.7 3.4e-06 26.8 4.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CDJ85802.1 - 2.6e-06 27.5 9.3 4.6e-06 26.7 9.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 CDJ85802.1 - 0.00052 19.7 7.1 0.0017 18.1 7.1 1.9 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 CDJ85802.1 - 0.00082 19.6 7.3 0.0023 18.2 6.9 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CDJ85802.1 - 0.004 17.2 3.3 0.0088 16.1 2.7 1.8 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 CDJ85802.1 - 0.013 15.4 3.0 0.013 15.4 3.0 1.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DUF5318 PF17249.2 CDJ85802.1 - 0.014 15.2 0.1 0.021 14.6 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5318) zf-RING_10 PF16685.5 CDJ85802.1 - 0.029 14.5 2.1 0.045 13.9 2.1 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 CDJ85802.1 - 0.23 11.3 4.0 0.38 10.6 4.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 CDJ85802.1 - 2 8.2 11.0 0.67 9.8 6.8 2.3 2 0 0 2 2 2 0 RING-like zinc finger DUF612 PF04747.12 CDJ85803.1 - 1.3e-10 41.0 78.3 1.3e-10 41.0 78.3 3.0 1 1 1 3 3 3 1 Protein of unknown function, DUF612 CTP_transf_like PF01467.26 CDJ85804.1 - 4.9e-47 159.7 0.1 1e-27 97.1 0.0 2.4 2 1 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 CDJ85804.1 - 0.0003 20.7 0.8 0.5 10.2 0.0 3.3 3 0 0 3 3 3 2 FAD synthetase Ion_trans PF00520.31 CDJ85805.1 - 9.9e-220 725.8 70.7 1.3e-66 224.3 14.1 5.1 4 1 1 5 5 5 5 Ion transport protein PKD_channel PF08016.12 CDJ85805.1 - 4.9e-13 48.6 58.9 7.6e-08 31.5 0.2 9.8 8 2 2 10 10 10 8 Polycystin cation channel DPM3 PF08285.11 CDJ85805.1 - 0.00022 21.4 3.7 0.27 11.5 0.1 4.3 3 0 0 3 3 3 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) FAM176 PF14851.6 CDJ85805.1 - 0.018 14.7 0.1 0.018 14.7 0.1 5.1 4 2 2 6 6 6 0 FAM176 family FtsL PF04999.13 CDJ85805.1 - 0.092 12.8 2.8 13 5.9 0.1 3.6 3 0 0 3 3 3 0 Cell division protein FtsL Ctr PF04145.15 CDJ85805.1 - 0.094 13.3 11.8 14 6.3 0.1 5.6 5 1 0 5 5 5 0 Ctr copper transporter family Connexin PF00029.19 CDJ85805.1 - 0.096 12.4 9.9 5.2 6.8 0.3 4.9 5 0 0 5 5 5 0 Connexin EphA2_TM PF14575.6 CDJ85805.1 - 0.15 13.0 1.2 3.4e+02 2.2 0.0 5.0 4 1 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain DUF2140 PF09911.9 CDJ85805.1 - 0.42 10.1 7.5 18 4.8 0.1 3.9 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2140) FixH PF05751.11 CDJ85805.1 - 1.5 8.8 7.0 6.2 6.8 1.3 3.6 3 0 0 3 3 3 0 FixH WD40 PF00400.32 CDJ85806.1 - 3.2e-29 100.5 22.0 1.5e-06 28.8 0.0 10.8 13 0 0 13 13 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ85806.1 - 5.4e-23 81.1 0.7 0.0011 19.2 0.1 9.7 4 2 6 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 CDJ85806.1 - 4.6e-20 71.9 0.7 7.6e-20 71.2 0.7 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.11 CDJ85806.1 - 1.7e-07 31.3 2.0 0.099 12.5 0.0 5.4 4 2 2 6 6 6 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CDJ85806.1 - 1.1e-05 24.5 3.3 0.026 13.5 0.0 5.2 3 1 2 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 CDJ85806.1 - 6.2e-05 22.9 0.2 0.096 12.4 0.0 3.2 3 0 0 3 3 3 1 Lipoprotein LpqB beta-propeller domain PD40 PF07676.12 CDJ85806.1 - 0.00055 19.8 1.1 1.2 9.2 0.0 4.6 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat DUF1513 PF07433.11 CDJ85806.1 - 0.00085 18.5 1.1 3.5 6.6 0.2 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1513) TFIIIC_delta PF12657.7 CDJ85806.1 - 0.0018 18.2 1.6 0.55 10.1 0.3 4.1 4 1 0 4 4 4 1 Transcription factor IIIC subunit delta N-term Nup160 PF11715.8 CDJ85806.1 - 0.0029 16.3 0.4 0.75 8.4 0.0 2.6 2 1 0 2 2 2 2 Nucleoporin Nup120/160 DPPIV_N PF00930.21 CDJ85806.1 - 0.024 13.4 0.0 0.16 10.7 0.0 2.4 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.9 CDJ85806.1 - 0.027 14.1 1.2 62 3.4 0.0 4.4 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Utp21 PF04192.12 CDJ85806.1 - 0.13 11.7 0.3 0.25 10.8 0.3 1.3 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain AIDA PF16168.5 CDJ85806.1 - 0.19 11.8 0.4 0.61 10.2 0.0 2.0 2 0 0 2 2 1 0 Adhesin of bacterial autotransporter system, probable stalk DEAD PF00270.29 CDJ85807.1 - 3.3e-39 134.5 0.5 1.2e-38 132.6 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ85807.1 - 6.6e-30 103.7 1.7 2.8e-26 92.0 0.1 3.4 3 0 0 3 3 3 2 Helicase conserved C-terminal domain UTP25 PF06862.12 CDJ85807.1 - 0.00017 20.5 0.8 0.022 13.5 0.2 2.8 2 1 1 3 3 3 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 CDJ85807.1 - 0.18 12.1 1.9 1.3 9.3 0.1 3.2 3 1 0 3 3 3 0 AAA domain Tail_spike_N PF18668.1 CDJ85808.1 - 0.18 11.7 1.2 14 5.6 0.1 2.3 1 1 1 2 2 2 0 Tail spike TSP1/Gp66 receptor binding N-terminal domain SCVP PF17619.2 CDJ85809.1 - 6e-24 84.7 1.0 7e-24 84.5 1.0 1.1 1 0 0 1 1 1 1 Secreted clade V proteins Hormone_recep PF00104.30 CDJ85810.1 - 9.7e-26 90.6 0.1 5.4e-16 58.8 0.0 2.6 3 0 0 3 3 3 2 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 CDJ85810.1 - 8.7e-25 87.0 12.9 1.7e-24 86.0 12.9 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Amino_oxidase PF01593.24 CDJ85811.1 - 3.1e-32 112.5 0.0 3.6e-32 112.2 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Ldl_recept_a PF00057.18 CDJ85812.1 - 4e-08 33.3 4.2 9.7e-08 32.1 4.2 1.7 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A CUB PF00431.20 CDJ85812.1 - 8.5e-08 32.5 0.0 3e-06 27.5 0.0 2.2 1 1 0 1 1 1 1 CUB domain Kinesin PF00225.23 CDJ85813.1 - 1.1e-115 386.2 0.0 1.9e-115 385.3 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ85813.1 - 1.7e-24 86.5 0.1 2.3e-23 82.8 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding Kinesin_assoc PF16183.5 CDJ85813.1 - 0.0028 17.8 6.2 0.027 14.6 5.7 2.7 2 1 0 2 2 2 1 Kinesin-associated DivIC PF04977.15 CDJ85813.1 - 0.0045 16.7 1.5 0.0045 16.7 1.5 4.4 1 1 3 4 4 4 1 Septum formation initiator AAA_30 PF13604.6 CDJ85813.1 - 0.0067 16.2 0.0 0.022 14.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CDJ85813.1 - 0.015 15.2 0.9 0.32 10.9 0.0 2.6 2 0 0 2 2 2 0 NACHT domain PYNP_C PF07831.13 CDJ85813.1 - 0.061 13.0 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain Flagellin_C PF00700.21 CDJ85813.1 - 0.94 9.9 5.0 0.81 10.1 0.1 3.0 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region AAA_16 PF13191.6 CDJ85813.1 - 1.4 9.2 0.0 1.4 9.2 0.0 2.7 2 1 0 2 2 1 0 AAA ATPase domain DUF724 PF05266.14 CDJ85813.1 - 3.1 7.6 21.0 2.4 7.9 7.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 CDJ85813.1 - 7.9 5.7 21.8 2 7.7 3.2 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) TRAM_LAG1_CLN8 PF03798.16 CDJ85814.1 - 2.9e-33 115.3 20.8 2.9e-33 115.3 20.8 1.4 2 0 0 2 2 2 1 TLC domain DUF4834 PF16118.5 CDJ85814.1 - 0.023 15.6 0.0 0.052 14.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) MIG-14_Wnt-bd PF06664.12 CDJ85815.1 - 6.6e-77 258.6 16.2 6.6e-77 258.6 16.2 1.4 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion Patched PF02460.18 CDJ85817.1 - 4.8e-279 927.9 8.1 5.5e-279 927.7 8.1 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 CDJ85817.1 - 1.3e-33 116.0 4.7 1.3e-33 116.0 4.7 2.8 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation FSAP_sig_propep PF03032.15 CDJ85818.1 - 0.2 11.7 0.0 0.25 11.4 0.0 1.1 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide FTHFS PF01268.19 CDJ85819.1 - 1.7e-104 350.0 0.0 2.5e-104 349.5 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase LSM PF01423.22 CDJ85820.1 - 6.4e-19 67.4 0.0 7.8e-19 67.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 CDJ85820.1 - 0.081 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain PLU-1 PF08429.11 CDJ85821.1 - 1.6e-38 132.8 14.6 2e-37 129.1 11.8 2.8 2 1 0 2 2 2 1 PLU-1-like protein JmjC PF02373.22 CDJ85821.1 - 4.3e-38 130.3 2.7 1.5e-37 128.5 2.7 2.1 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 CDJ85821.1 - 1.4e-16 60.1 48.4 3e-11 43.0 9.0 4.0 4 0 0 4 4 4 3 PHD-finger zf-C5HC2 PF02928.16 CDJ85821.1 - 1.4e-15 57.4 8.3 1.4e-15 57.4 8.3 2.7 2 0 0 2 2 2 1 C5HC2 zinc finger JmjN PF02375.17 CDJ85821.1 - 3.6e-15 55.6 1.4 1.1e-14 54.1 1.0 2.1 2 0 0 2 2 2 1 jmjN domain ARID PF01388.21 CDJ85821.1 - 4.7e-14 52.8 0.4 1.1e-13 51.6 0.4 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Acetyltransf_1 PF00583.25 CDJ85822.1 - 2.1e-05 24.7 0.0 3.9e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDJ85822.1 - 0.0015 18.9 0.0 0.0026 18.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CDJ85822.1 - 0.021 14.9 0.0 0.049 13.7 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDJ85822.1 - 0.066 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Mito_fiss_reg PF05308.11 CDJ85822.1 - 0.089 12.9 3.8 0.13 12.3 3.8 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Dimer_Tnp_hAT PF05699.14 CDJ85822.1 - 0.14 11.9 0.3 0.76 9.6 0.3 2.2 1 1 0 1 1 1 0 hAT family C-terminal dimerisation region Acetyltransf_CG PF14542.6 CDJ85822.1 - 0.18 12.0 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PRIMA1 PF16101.5 CDJ85822.1 - 0.27 11.3 4.8 0.28 11.2 1.2 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Pol_alpha_B_N PF08418.10 CDJ85822.1 - 0.4 10.6 2.4 0.55 10.1 2.4 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal dCMP_cyt_deam_1 PF00383.23 CDJ85823.1 - 3.6e-20 71.7 0.0 5.5e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 CDJ85823.1 - 5.9e-11 42.7 0.3 1.9e-08 34.6 0.0 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 CDJ85823.1 - 7.4e-05 22.4 2.3 0.0015 18.2 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases CNH PF00780.22 CDJ85824.1 - 4.2e-40 138.1 0.0 1.5e-39 136.3 0.0 1.9 1 0 0 1 1 1 1 CNH domain PH PF00169.29 CDJ85824.1 - 7.2e-09 36.1 0.7 3.2e-08 34.0 0.0 2.5 2 0 0 2 2 2 1 PH domain FlaC_arch PF05377.11 CDJ85824.1 - 0.003 17.9 2.0 0.003 17.9 2.0 10.5 9 4 1 11 11 11 1 Flagella accessory protein C (FlaC) ADIP PF11559.8 CDJ85824.1 - 0.005 16.9 5.9 0.005 16.9 5.9 8.5 1 1 6 8 8 8 3 Afadin- and alpha -actinin-Binding C1_1 PF00130.22 CDJ85824.1 - 0.0072 16.2 8.0 0.02 14.8 8.0 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) GlcNAc-1_reg PF18440.1 CDJ85824.1 - 0.87 9.9 10.3 0.17 12.2 0.6 4.3 4 0 0 4 4 4 0 Putative GlcNAc-1 phosphotransferase regulatory domain Peptidase_A4 PF01828.17 CDJ85825.1 - 0.069 12.6 0.0 0.1 12.1 0.0 1.3 1 1 0 1 1 1 0 Peptidase A4 family LRR_6 PF13516.6 CDJ85826.1 - 2.4e-14 52.1 5.7 0.001 19.0 0.0 7.9 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.7 CDJ85826.1 - 1.6e-05 25.1 7.3 0.051 14.0 1.5 4.8 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ85826.1 - 5.6e-05 22.8 5.2 0.0064 16.2 0.2 4.4 3 2 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.33 CDJ85826.1 - 0.00019 21.5 0.6 51 5.0 0.0 5.4 6 0 0 6 6 6 0 Leucine Rich Repeat DUF4326 PF14216.6 CDJ85826.1 - 0.071 13.8 0.1 0.15 12.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4326) LRR_6 PF13516.6 CDJ85827.1 - 0.011 15.7 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 Leucine Rich repeat DIM1 PF02966.16 CDJ85828.1 - 4.6e-66 220.6 0.0 5.1e-66 220.5 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 CDJ85828.1 - 3.4e-05 23.8 0.0 4.5e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CDJ85828.1 - 0.012 15.9 0.2 0.018 15.4 0.2 1.3 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_7 PF13899.6 CDJ85828.1 - 0.017 15.3 0.0 0.033 14.4 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin-like Med21 PF11221.8 CDJ85829.1 - 1.1e-14 55.0 1.8 2e-12 47.6 1.8 2.0 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Cullin_binding PF03556.15 CDJ85830.1 - 1.1e-34 119.5 2.9 1.5e-34 119.0 0.2 2.1 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.6 CDJ85830.1 - 4.9e-10 39.1 0.8 1.2e-09 37.8 0.0 2.1 3 0 0 3 3 3 1 UBA-like domain EELM2 PF15863.5 CDJ85830.1 - 0.029 14.5 0.2 0.045 13.9 0.2 1.3 1 0 0 1 1 1 0 Extended EGL-27 and MTA1 homology domain TAP_C PF03943.13 CDJ85830.1 - 0.03 14.0 1.8 0.047 13.3 0.9 1.9 2 0 0 2 2 2 0 TAP C-terminal domain CD20 PF04103.15 CDJ85831.1 - 8.4e-24 84.4 9.4 9.9e-24 84.2 9.4 1.1 1 0 0 1 1 1 1 CD20-like family CBP PF12192.8 CDJ85831.1 - 0.82 9.9 3.4 3.7 7.8 0.3 2.2 2 0 0 2 2 2 0 Fungal calcium binding protein CRPA PF05745.11 CDJ85831.1 - 2.9 7.9 8.2 0.37 10.8 1.4 2.1 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Hormone_recep PF00104.30 CDJ85832.1 - 4e-06 26.5 0.6 6.6e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor SF3A3 PF16837.5 CDJ85832.1 - 0.38 11.3 2.8 1.3 9.6 2.8 2.0 1 1 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 S-antigen PF05756.11 CDJ85834.1 - 1.2 9.6 4.8 2.6 8.5 4.8 1.6 1 0 0 1 1 1 0 S-antigen protein zf-C3HC4_2 PF13923.6 CDJ85835.1 - 8.5e-13 47.9 10.0 1.8e-12 46.8 10.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ85835.1 - 1.3e-09 37.7 10.2 2.6e-09 36.8 10.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ85835.1 - 2.9e-08 33.9 8.7 6.8e-08 32.7 8.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDJ85835.1 - 1.9e-06 27.6 6.9 3.4e-06 26.8 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ85835.1 - 5.3e-06 26.3 9.1 1.1e-05 25.3 9.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDJ85835.1 - 6.2e-06 26.1 8.7 1.5e-05 24.9 8.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDJ85835.1 - 0.00011 22.3 7.9 0.00027 21.0 7.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 CDJ85835.1 - 0.00021 21.1 3.1 0.0006 19.6 3.1 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 CDJ85835.1 - 0.0033 17.2 6.5 0.0084 15.9 6.5 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 CDJ85835.1 - 0.0076 16.5 7.7 0.036 14.3 7.7 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 CDJ85835.1 - 0.013 15.4 3.3 0.026 14.4 3.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Nop14 PF04147.12 CDJ85835.1 - 0.022 13.0 11.7 0.029 12.6 11.7 1.1 1 0 0 1 1 1 0 Nop14-like family Prok-RING_4 PF14447.6 CDJ85835.1 - 0.087 12.7 8.9 2.4 8.1 9.1 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 RAWUL PF16207.5 CDJ85835.1 - 0.11 13.2 0.0 0.2 12.3 0.0 1.5 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-RING_10 PF16685.5 CDJ85835.1 - 0.15 12.2 6.6 0.34 11.1 6.6 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 BUD22 PF09073.10 CDJ85835.1 - 0.17 11.2 14.3 0.27 10.6 14.3 1.2 1 0 0 1 1 1 0 BUD22 zf-C3HC4_5 PF17121.5 CDJ85835.1 - 0.18 11.7 5.3 0.41 10.6 5.3 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 CDJ85835.1 - 2.4 8.4 5.5 3.8 7.7 0.7 3.3 3 1 1 4 4 3 0 U-box domain zf-C4_Topoisom PF01396.19 CDJ85835.1 - 4.7 7.1 6.3 0.48 10.2 0.9 2.1 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-RING-like PF08746.11 CDJ85835.1 - 4.8 7.6 6.7 9.7 6.6 6.7 1.6 1 0 0 1 1 1 0 RING-like domain PIP5K PF01504.18 CDJ85836.1 - 7.1e-44 150.1 3.3 1.4e-37 129.4 2.1 2.4 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase FYVE PF01363.21 CDJ85836.1 - 5.8e-17 61.6 9.7 5.8e-17 61.6 9.7 2.3 2 0 0 2 2 2 1 FYVE zinc finger Cpn60_TCP1 PF00118.24 CDJ85836.1 - 4.6e-08 32.1 0.0 3.7e-07 29.2 0.0 2.0 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family TPT PF03151.16 CDJ85837.1 - 8.2e-17 61.5 10.0 9.5e-17 61.3 10.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CDJ85837.1 - 3.6e-07 30.4 23.7 0.00035 20.8 3.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CDJ85837.1 - 0.0011 18.3 9.5 0.0028 16.9 9.5 1.8 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 CDJ85837.1 - 0.0013 18.0 9.1 0.0055 16.0 9.1 1.9 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport TTR-52 PF01060.23 CDJ85838.1 - 2.5e-21 76.2 0.0 3.8e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Transthyretin-like family MH2 PF03166.14 CDJ85839.1 - 1.5e-49 168.7 0.2 1.5e-49 168.7 0.2 1.8 2 0 0 2 2 2 1 MH2 domain MH1 PF03165.16 CDJ85839.1 - 2.3e-33 114.5 1.2 6.7e-33 113.0 1.2 1.9 1 0 0 1 1 1 1 MH1 domain DUF1325 PF07039.11 CDJ85839.1 - 1.8e-22 79.8 0.0 6.2e-22 78.1 0.0 1.9 1 0 0 1 1 1 1 SGF29 tudor-like domain NAM-associated PF14303.6 CDJ85839.1 - 1.9 9.2 6.7 0.38 11.5 2.0 2.3 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain NikR_C PF08753.11 CDJ85839.1 - 2.7 8.2 5.3 39 4.5 0.0 2.6 2 0 0 2 2 2 0 NikR C terminal nickel binding domain AMP-binding PF00501.28 CDJ85840.1 - 6.1e-46 156.9 0.0 7.9e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ85840.1 - 0.0031 18.5 0.0 0.094 13.7 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain HTH_Tnp_Tc3_2 PF01498.18 CDJ85841.1 - 1.9e-22 79.3 1.2 1.9e-22 79.3 1.2 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 CDJ85841.1 - 3.1e-16 59.5 0.0 5.8e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 CDJ85841.1 - 2.1e-09 37.9 5.9 3.6e-08 33.9 0.7 2.8 1 1 1 2 2 2 1 Homeodomain-like domain PAX PF00292.18 CDJ85841.1 - 1.4e-08 34.7 0.3 2.6e-08 33.8 0.3 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 CDJ85841.1 - 6.7e-08 32.1 1.2 1.8e-05 24.4 0.1 2.6 2 0 0 2 2 2 2 Homeodomain-like domain HTH_29 PF13551.6 CDJ85841.1 - 1.5e-05 24.9 2.3 0.00025 21.0 0.4 2.5 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 CDJ85841.1 - 0.00019 21.5 0.8 0.011 15.8 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 CDJ85841.1 - 0.0021 17.7 0.5 0.088 12.5 0.1 2.6 2 1 0 2 2 2 1 Sigma-70, region 4 HTH_24 PF13412.6 CDJ85841.1 - 0.0028 17.2 3.2 1.9 8.1 1.0 3.3 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding CENP-B_N PF04218.13 CDJ85841.1 - 0.005 16.4 0.1 1.1 8.9 0.0 2.5 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain MarR_2 PF12802.7 CDJ85841.1 - 0.0072 16.2 2.7 0.47 10.4 0.3 2.5 2 0 0 2 2 2 1 MarR family HTH_21 PF13276.6 CDJ85841.1 - 0.015 15.5 0.1 0.064 13.4 0.0 2.1 2 0 0 2 2 2 0 HTH-like domain GerE PF00196.19 CDJ85841.1 - 0.025 14.1 0.1 0.81 9.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_12 PF08461.10 CDJ85841.1 - 0.027 14.4 0.1 0.059 13.3 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Sigma70_r4 PF04545.16 CDJ85841.1 - 0.046 13.2 0.3 2 8.0 0.3 2.6 2 1 0 2 2 2 0 Sigma-70, region 4 TrmB PF01978.19 CDJ85841.1 - 0.1 12.5 0.0 0.46 10.4 0.0 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_38 PF13936.6 CDJ85841.1 - 0.21 11.3 3.1 0.33 10.7 0.4 2.6 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.15 CDJ85841.1 - 2.1 8.5 4.0 25 5.1 0.1 3.0 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase Nucleoside_tran PF01733.18 CDJ85842.1 - 3.8e-61 207.1 25.4 1.2e-60 205.6 18.8 2.5 2 1 0 2 2 2 1 Nucleoside transporter Bestrophin PF01062.21 CDJ85843.1 - 6.6e-77 258.8 4.5 1e-76 258.2 4.5 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel MOSC PF03473.17 CDJ85844.1 - 2.9e-28 98.5 0.0 8.4e-28 97.0 0.0 1.7 2 0 0 2 2 2 1 MOSC domain MOSC_N PF03476.16 CDJ85844.1 - 1.1e-23 83.4 0.0 1.6e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain HPS3_N PF14761.6 CDJ85844.1 - 0.12 11.9 0.1 0.29 10.6 0.0 1.6 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 DUF4440 PF14534.6 CDJ85845.1 - 0.00028 21.2 0.4 0.03 14.7 0.2 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 CDJ85845.1 - 0.027 14.6 2.5 2.3 8.4 0.1 2.1 1 1 1 2 2 2 0 SnoaL-like domain DUF4440 PF14534.6 CDJ85846.1 - 1.7e-06 28.4 0.2 0.00073 19.9 0.2 2.3 1 1 2 3 3 3 2 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 CDJ85846.1 - 0.041 14.0 1.5 4.9 7.3 0.4 2.1 1 1 1 2 2 2 0 SnoaL-like domain LIM PF00412.22 CDJ85847.1 - 2.6e-19 69.2 13.6 1.1e-12 47.9 2.6 2.7 2 1 0 2 2 2 2 LIM domain VHP PF02209.19 CDJ85847.1 - 2.7e-15 56.1 1.0 5.7e-15 55.1 1.0 1.6 1 0 0 1 1 1 1 Villin headpiece domain AbLIM_anchor PF16182.5 CDJ85847.1 - 0.00064 19.6 1.8 0.00066 19.6 1.2 1.3 1 1 0 1 1 1 1 Putative adherens-junction anchoring region of AbLIM C1_1 PF00130.22 CDJ85847.1 - 0.87 9.5 12.2 1.3 8.9 1.8 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TNFR_c6 PF00020.18 CDJ85847.1 - 9.3 6.8 14.0 4.1 7.9 0.5 3.3 3 1 1 4 4 4 0 TNFR/NGFR cysteine-rich region CAP PF00188.26 CDJ85848.1 - 1.2e-13 51.9 0.2 2.5e-13 50.9 0.2 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Ribosomal_L19 PF01245.20 CDJ85848.1 - 0.17 11.8 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L19 Astacin PF01400.24 CDJ85849.1 - 1.4e-60 204.2 0.2 2e-60 203.7 0.2 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 CDJ85849.1 - 9.6e-06 25.5 1.9 0.0071 16.2 0.4 2.4 2 0 0 2 2 2 2 Matrixin CUB PF00431.20 CDJ85849.1 - 7.7e-05 23.0 0.3 0.0029 17.9 0.0 2.6 3 0 0 3 3 3 1 CUB domain Reprolysin_4 PF13583.6 CDJ85849.1 - 0.0011 18.6 0.1 0.0019 17.9 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CDJ85849.1 - 0.0017 18.5 0.1 0.003 17.8 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CDJ85849.1 - 0.02 15.4 0.1 0.046 14.2 0.1 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 CDJ85849.1 - 0.059 13.3 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.13 CDJ85849.1 - 2.4 8.6 10.4 5.5 7.5 10.4 1.6 1 0 0 1 1 1 0 EGF-like domain Abhydrolase_1 PF00561.20 CDJ85850.1 - 3.9e-09 36.5 0.0 5e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ85850.1 - 5.1e-05 22.6 0.0 0.00025 20.4 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 VirJ PF06057.11 CDJ85850.1 - 0.067 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF915 PF06028.11 CDJ85850.1 - 0.082 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Ndr PF03096.14 CDJ85850.1 - 0.12 11.0 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Ndr family Cutinase PF01083.22 CDJ85850.1 - 0.21 11.6 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Cutinase MutS_V PF00488.21 CDJ85851.1 - 7e-68 228.4 0.0 1.3e-67 227.5 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CDJ85851.1 - 1.6e-31 110.0 0.4 1.2e-30 107.2 0.3 2.3 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 CDJ85851.1 - 2.2e-31 108.4 0.2 4.3e-31 107.5 0.2 1.5 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 CDJ85851.1 - 6.6e-13 48.8 0.4 1.5e-12 47.6 0.4 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 CDJ85851.1 - 1.5e-08 35.0 0.3 7.3e-08 32.8 0.3 2.2 1 1 0 1 1 1 1 MutS domain II DIOX_N PF14226.6 CDJ85851.1 - 0.0036 18.0 0.1 0.023 15.5 0.0 2.3 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal AAA_29 PF13555.6 CDJ85851.1 - 0.11 12.2 0.1 0.31 10.8 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DTC PF18102.1 CDJ85851.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Deltex C-terminal domain 4_1_CTD PF05902.13 CDJ85853.1 - 3.5e-27 94.6 6.0 3.5e-27 94.6 6.0 2.3 2 0 0 2 2 2 1 4.1 protein C-terminal domain (CTD) TLP1_add_C PF18313.1 CDJ85853.1 - 0.11 12.5 0.9 0.34 10.9 0.1 2.2 2 0 0 2 2 2 0 Thiolase-like protein type 1 additional C-terminal domain DUF5463 PF17551.2 CDJ85853.1 - 0.25 11.3 1.0 0.54 10.2 1.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5463) zf_UBZ PF18439.1 CDJ85854.1 - 0.00059 19.4 3.5 0.61 9.7 0.1 3.4 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 CDJ85854.1 - 0.0032 17.3 0.9 0.0032 17.3 0.9 3.5 4 0 0 4 4 4 1 zinc-finger of a C2HC-type PRP21_like_P PF12230.8 CDJ85854.1 - 0.056 13.3 0.3 1.7 8.4 0.1 2.1 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein zf-Di19 PF05605.12 CDJ85854.1 - 0.2 12.0 0.6 0.2 12.0 0.6 2.9 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-CpG_bind_C PF12269.8 CDJ85854.1 - 0.88 9.3 6.2 0.55 10.0 0.2 2.5 2 1 1 3 3 3 0 CpG binding protein zinc finger C terminal domain UPF0547 PF10571.9 CDJ85854.1 - 1.1 9.4 4.4 7.2 6.8 0.2 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DUF2318 PF10080.9 CDJ85854.1 - 1.5 8.9 4.4 17 5.6 0.4 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) XAF1_C PF18608.1 CDJ85854.1 - 1.6 8.3 12.4 5.8 6.6 0.8 3.6 3 1 0 3 3 3 0 XIAP-associated factor 1 C-terminal domain DZR PF12773.7 CDJ85854.1 - 1.7 8.7 12.1 25 5.0 7.4 3.2 2 1 0 2 2 2 0 Double zinc ribbon DNA_RNApol_7kD PF03604.13 CDJ85854.1 - 2 8.2 7.1 0.34 10.6 0.4 2.9 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zinc-ribbons_6 PF07191.12 CDJ85854.1 - 2.7 8.1 10.0 9.6 6.3 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbons HypA PF01155.19 CDJ85854.1 - 2.7 8.0 7.3 8.9 6.4 0.3 3.0 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA bZIP_2 PF07716.15 CDJ85855.1 - 3.6e-14 52.6 21.6 4.8e-14 52.2 21.6 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CDJ85855.1 - 2.3e-05 24.4 14.4 3.1e-05 24.0 14.4 1.1 1 0 0 1 1 1 1 bZIP transcription factor Filament PF00038.21 CDJ85855.1 - 0.0012 18.6 8.0 0.0013 18.4 8.0 1.1 1 0 0 1 1 1 1 Intermediate filament protein KLRAQ PF10205.9 CDJ85855.1 - 0.0054 16.9 5.0 0.0062 16.7 5.0 1.3 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein bZIP_Maf PF03131.17 CDJ85855.1 - 0.0067 16.9 8.2 0.0084 16.6 8.2 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor HeLo PF14479.6 CDJ85855.1 - 0.0098 15.7 1.8 0.011 15.5 1.8 1.0 1 0 0 1 1 1 1 Prion-inhibition and propagation DUF3450 PF11932.8 CDJ85855.1 - 0.01 15.2 5.5 0.012 15.0 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DDRGK PF09756.9 CDJ85855.1 - 0.016 14.8 12.9 0.018 14.6 12.9 1.0 1 0 0 1 1 1 0 DDRGK domain HALZ PF02183.18 CDJ85855.1 - 0.029 14.6 2.1 0.029 14.6 2.1 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4618 PF15397.6 CDJ85855.1 - 0.041 13.3 8.4 0.049 13.0 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) YlbD_coat PF14071.6 CDJ85855.1 - 0.051 13.8 4.1 0.067 13.5 4.1 1.1 1 0 0 1 1 1 0 Putative coat protein MIF4G_like_2 PF09090.11 CDJ85855.1 - 0.09 12.2 4.6 0.094 12.2 4.6 1.0 1 0 0 1 1 1 0 MIF4G like APG6_N PF17675.1 CDJ85855.1 - 0.11 13.0 11.7 0.14 12.6 11.7 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region Tho2 PF11262.8 CDJ85855.1 - 0.14 11.4 5.9 0.16 11.2 5.9 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4140 PF13600.6 CDJ85855.1 - 0.22 11.9 4.5 0.33 11.4 4.5 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.6 CDJ85855.1 - 0.23 10.8 3.4 0.27 10.6 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) WDCP PF15390.6 CDJ85855.1 - 0.32 9.3 3.1 0.34 9.3 3.1 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF4094 PF13334.6 CDJ85855.1 - 0.32 11.4 3.8 0.4 11.1 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DivIC PF04977.15 CDJ85855.1 - 0.53 10.1 11.7 0.11 12.3 7.7 1.8 1 1 1 2 2 2 0 Septum formation initiator FAM76 PF16046.5 CDJ85855.1 - 0.65 9.3 8.1 0.78 9.0 8.1 1.1 1 0 0 1 1 1 0 FAM76 protein EURL PF06937.11 CDJ85855.1 - 0.74 9.2 6.5 0.88 8.9 6.5 1.0 1 0 0 1 1 1 0 EURL protein TMPIT PF07851.13 CDJ85855.1 - 1.2 8.3 4.6 1.3 8.2 4.6 1.0 1 0 0 1 1 1 0 TMPIT-like protein CLN3 PF02487.17 CDJ85855.1 - 1.8 7.5 4.1 2 7.4 4.1 1.0 1 0 0 1 1 1 0 CLN3 protein PRKCSH-like PF12999.7 CDJ85855.1 - 1.8 8.3 6.7 2.4 7.9 6.7 1.2 1 0 0 1 1 1 0 Glucosidase II beta subunit-like MscS_TM PF12794.7 CDJ85855.1 - 2.3 7.0 4.6 2.6 6.8 4.6 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Sas10_Utp3 PF04000.15 CDJ85856.1 - 9.1e-10 39.0 0.0 4.4e-09 36.9 0.0 2.2 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DUF1043 PF06295.12 CDJ85856.1 - 5.8 6.9 8.5 1 9.3 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF4611 PF15387.6 CDJ85856.1 - 6 7.2 14.1 0.11 12.7 4.1 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4611) HTH_9 PF08221.11 CDJ85857.1 - 1.5e-20 73.0 5.1 4.1e-10 39.6 0.1 3.8 4 0 0 4 4 4 3 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 CDJ85857.1 - 5.5e-15 55.8 0.0 6.5e-14 52.3 0.0 2.5 2 1 0 2 2 2 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 CDJ85857.1 - 1.5e-05 24.8 4.6 5.7e-05 22.9 0.2 3.5 3 1 1 4 4 4 1 TFIIE alpha subunit 7tm_1 PF00001.21 CDJ85858.1 - 6e-08 32.3 4.0 7.3e-08 32.0 4.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDJ85858.1 - 6.6e-06 25.6 7.1 7.9e-06 25.4 7.1 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF3169 PF11368.8 CDJ85858.1 - 0.0023 17.5 2.9 0.003 17.1 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) 7TM_GPCR_Srsx PF10320.9 CDJ85858.1 - 0.0068 15.8 8.6 0.017 14.6 7.7 1.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx Linker_histone PF00538.19 CDJ85859.1 - 1.6e-25 89.3 0.8 1.6e-25 89.3 0.8 1.9 2 0 0 2 2 2 1 linker histone H1 and H5 family DUF4777 PF16007.5 CDJ85859.1 - 0.017 15.4 0.0 0.024 14.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) LIM PF00412.22 CDJ85860.1 - 4.2e-08 33.3 4.4 4.7e-08 33.1 4.4 1.1 1 0 0 1 1 1 1 LIM domain zf-C2H2_3 PF13878.6 CDJ85860.1 - 0.29 11.0 8.0 1.8 8.4 0.8 2.5 2 1 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Lar_restr_allev PF14354.6 CDJ85860.1 - 0.38 11.1 6.0 28 5.2 6.0 2.1 1 1 0 1 1 1 0 Restriction alleviation protein Lar PHD_2 PF13831.6 CDJ85860.1 - 3.7 7.2 9.8 6.3 6.4 1.3 2.8 2 2 0 2 2 2 0 PHD-finger LIM PF00412.22 CDJ85861.1 - 6e-26 90.4 46.7 2.2e-11 43.8 10.1 5.8 7 1 0 7 7 7 3 LIM domain Exostosin PF03016.15 CDJ85863.1 - 6.4e-51 173.3 0.2 1.1e-50 172.6 0.2 1.3 1 0 0 1 1 1 1 Exostosin family Glyco_transf_64 PF09258.10 CDJ85863.1 - 1.3e-07 31.2 0.0 2.7e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain AA_permease PF00324.21 CDJ85865.1 - 1.7e-65 221.5 47.2 3.9e-65 220.3 47.2 1.5 1 1 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 CDJ85865.1 - 4.3e-27 95.2 1.9 9.6e-13 47.9 0.0 4.0 4 0 0 4 4 4 4 Solute carrier family 12 AA_permease_2 PF13520.6 CDJ85865.1 - 3.1e-14 52.7 46.9 5e-14 52.0 46.9 1.3 1 0 0 1 1 1 1 Amino acid permease Lipase_GDSL_2 PF13472.6 CDJ85865.1 - 0.21 12.0 0.0 0.37 11.2 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family PID PF00640.23 CDJ85867.1 - 5.8e-17 62.0 0.0 7.7e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PQ-loop PF04193.14 CDJ85869.1 - 0.033 13.9 0.1 0.041 13.7 0.1 1.3 1 0 0 1 1 1 0 PQ loop repeat CLPTM1 PF05602.12 CDJ85870.1 - 4.1e-67 227.1 5.3 4.4e-67 227.0 5.3 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) AP_endonuc_2 PF01261.24 CDJ85871.1 - 0.022 14.2 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF3602 PF12223.8 CDJ85872.1 - 0.036 14.7 0.3 0.08 13.6 0.1 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3602) HTH_48 PF17906.1 CDJ85872.1 - 0.049 13.8 0.4 0.17 12.0 0.4 1.9 1 1 0 1 1 1 0 HTH domain in Mos1 transposase DUF4817 PF16087.5 CDJ85872.1 - 0.11 12.3 0.2 0.2 11.5 0.2 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain (DUF4817) FYVE PF01363.21 CDJ85873.1 - 3e-19 68.9 8.4 6e-19 67.9 8.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 CDJ85873.1 - 3.8e-09 37.0 0.0 6.3e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.16 CDJ85873.1 - 0.0035 17.5 4.8 0.0073 16.5 4.8 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger PH_13 PF16652.5 CDJ85873.1 - 0.0057 16.5 0.7 0.2 11.4 0.7 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_16 PF17838.1 CDJ85873.1 - 0.017 14.9 0.1 0.14 12.0 0.1 2.0 1 1 0 1 1 1 0 PH domain IQ_SEC7_PH PF16453.5 CDJ85873.1 - 0.029 14.3 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 PH domain Ephrin_rec_like PF07699.13 CDJ85873.1 - 0.077 12.8 4.6 0.5 10.2 0.7 2.5 1 1 1 2 2 2 0 Putative ephrin-receptor like DZR PF12773.7 CDJ85873.1 - 1.5 8.9 10.0 15 5.7 0.5 2.8 1 1 2 3 3 3 0 Double zinc ribbon zf-B_box PF00643.24 CDJ85873.1 - 3.8 7.7 9.1 1.4 9.2 5.4 2.1 2 1 0 2 2 2 0 B-box zinc finger DUF229 PF02995.17 CDJ85874.1 - 6.2e-114 381.3 0.1 2.5e-113 379.3 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 CDJ85874.1 - 1.4e-06 27.9 1.4 1.2e-05 24.9 0.1 2.2 1 1 1 2 2 2 1 Sulfatase DUF1501 PF07394.12 CDJ85874.1 - 0.0015 17.7 0.1 0.0025 17.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Phosphodiest PF01663.22 CDJ85874.1 - 0.006 16.2 0.1 0.0092 15.6 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Ras PF00071.22 CDJ85875.1 - 4.2e-37 127.2 0.1 5e-37 127.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ85875.1 - 5e-12 46.1 0.0 7.3e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ85875.1 - 2.6e-06 27.0 0.0 2.8e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CDJ85875.1 - 0.0015 18.0 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATPase_2 PF01637.18 CDJ85875.1 - 0.006 16.5 0.1 0.07 13.0 0.0 2.0 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea ATP-synt_ab PF00006.25 CDJ85875.1 - 0.016 14.9 0.2 2.3 7.8 0.0 2.2 1 1 1 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.23 CDJ85875.1 - 0.032 14.3 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 CDJ85875.1 - 0.089 12.2 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 CDJ85875.1 - 0.12 12.6 0.0 0.19 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CDJ85875.1 - 0.13 12.5 0.1 0.5 10.6 0.0 2.0 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.6 CDJ85875.1 - 0.17 12.3 0.0 0.38 11.1 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain Synaptobrevin PF00957.21 CDJ85876.1 - 3e-26 91.0 5.7 3e-26 91.0 5.7 1.5 1 1 0 1 1 1 1 Synaptobrevin SGIII PF15467.6 CDJ85876.1 - 0.00044 19.6 0.2 0.00053 19.4 0.2 1.0 1 0 0 1 1 1 1 Secretogranin-3 EVI2A PF05399.11 CDJ85876.1 - 0.0063 16.1 0.1 0.0078 15.8 0.1 1.1 1 0 0 1 1 1 1 Ectropic viral integration site 2A protein (EVI2A) RIFIN PF02009.16 CDJ85876.1 - 0.0072 16.3 0.4 0.0086 16.0 0.4 1.0 1 0 0 1 1 1 1 Rifin Spc7 PF08317.11 CDJ85876.1 - 0.0084 15.0 1.3 0.01 14.8 1.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Sec5 PF15469.6 CDJ85876.1 - 0.01 15.7 0.8 0.015 15.1 0.8 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec5 KASH_CCD PF14662.6 CDJ85876.1 - 0.01 15.7 1.6 0.012 15.5 1.6 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF5345 PF17280.2 CDJ85876.1 - 0.077 13.0 0.1 0.077 13.0 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5345) m04gp34like PF12216.8 CDJ85876.1 - 0.11 12.1 0.6 0.15 11.6 0.4 1.3 1 1 0 1 1 1 0 Immune evasion protein HSBP1 PF06825.12 CDJ85876.1 - 1.3 9.0 6.1 8.1 6.4 0.2 2.6 1 1 1 2 2 2 0 Heat shock factor binding protein 1 TMEM156 PF15106.6 CDJ85876.1 - 1.9 7.8 6.7 2.5 7.5 6.5 1.4 1 1 0 1 1 1 0 TMEM156 protein family XhlA PF10779.9 CDJ85876.1 - 6.8 7.0 9.5 3.5 7.9 0.4 2.6 1 1 1 2 2 2 0 Haemolysin XhlA Amino_oxidase PF01593.24 CDJ85878.1 - 6.2e-11 42.2 0.2 1.7e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ85878.1 - 2.9e-10 40.2 0.4 7.4e-10 38.9 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CDJ85878.1 - 1.3e-08 34.8 2.3 3.6e-06 26.8 2.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CDJ85878.1 - 5.9e-07 29.2 1.7 7.3e-07 28.9 0.7 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CDJ85878.1 - 9.2e-07 28.3 5.0 2.2e-05 23.7 3.3 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 CDJ85878.1 - 1.3e-06 27.8 0.2 2.5e-06 26.9 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 CDJ85878.1 - 9.3e-06 25.1 0.4 5.2e-05 22.7 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 CDJ85878.1 - 3.1e-05 23.4 0.1 0.00025 20.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CDJ85878.1 - 0.00029 20.0 3.1 0.0038 16.4 1.9 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 CDJ85878.1 - 0.00036 19.4 1.6 0.0012 17.7 0.5 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 CDJ85878.1 - 0.00055 20.4 2.4 0.0077 16.8 0.9 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 CDJ85878.1 - 0.017 13.7 0.0 2.2 6.7 0.0 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor MCRA PF06100.11 CDJ85878.1 - 0.039 12.7 0.2 0.065 12.0 0.2 1.2 1 0 0 1 1 1 0 MCRA family Pyr_redox_3 PF13738.6 CDJ85878.1 - 0.086 12.1 0.7 0.18 11.0 0.7 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CDJ85878.1 - 0.093 11.6 2.2 0.23 10.3 0.7 1.9 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 CDJ85878.1 - 0.1 11.6 0.5 0.19 10.7 0.5 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 CDJ85878.1 - 0.18 11.1 0.2 0.33 10.2 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Cadherin PF00028.17 CDJ85880.1 - 8.5e-193 625.5 21.3 2.7e-20 72.6 0.1 18.6 17 1 1 18 18 18 18 Cadherin domain Laminin_G_2 PF02210.24 CDJ85880.1 - 1.6e-18 67.5 0.0 7.8e-18 65.3 0.0 2.3 2 0 0 2 2 2 1 Laminin G domain Cadherin_3 PF16184.5 CDJ85880.1 - 9e-16 57.9 16.5 1.2 9.1 0.0 12.0 12 0 0 12 12 12 5 Cadherin-like Laminin_G_1 PF00054.23 CDJ85880.1 - 1.8e-15 57.3 0.0 4.9e-15 55.9 0.0 1.8 1 0 0 1 1 1 1 Laminin G domain RET_CLD1 PF17756.1 CDJ85880.1 - 2.1e-14 53.9 0.0 0.55 10.5 0.0 9.2 11 0 0 11 11 11 4 RET Cadherin like domain 1 Cadherin_2 PF08266.12 CDJ85880.1 - 4.4e-11 42.5 0.3 0.059 13.2 0.0 8.7 11 1 0 11 11 11 2 Cadherin-like EGF PF00008.27 CDJ85880.1 - 3.1e-10 40.2 69.8 8.5e-06 26.0 8.0 6.7 7 0 0 7 7 7 5 EGF-like domain Flu_B_NS1 PF02942.14 CDJ85880.1 - 0.003 16.7 0.1 3.2 6.8 0.0 2.7 2 0 0 2 2 2 2 Influenza B non-structural protein (NS1) Laminin_G_3 PF13385.6 CDJ85880.1 - 0.03 14.5 0.1 0.12 12.5 0.1 2.1 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily DUF1681 PF07933.14 CDJ85880.1 - 0.072 12.8 0.1 0.2 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1681) Y_phosphatase PF00102.27 CDJ85881.1 - 1.5e-73 247.2 0.0 2.1e-73 246.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase SH2 PF00017.24 CDJ85881.1 - 1.6e-37 127.4 0.2 1.2e-17 63.7 0.0 2.5 2 0 0 2 2 2 2 SH2 domain SH2_2 PF14633.6 CDJ85881.1 - 2.2e-08 33.8 0.0 0.00051 19.5 0.0 2.5 1 1 0 2 2 2 2 SH2 domain DSPc PF00782.20 CDJ85881.1 - 5.9e-06 26.1 0.0 1.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CDJ85881.1 - 0.00065 19.8 0.1 0.005 17.0 0.1 2.2 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 CDJ85881.1 - 0.012 15.6 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Pkinase PF00069.25 CDJ85882.1 - 3e-15 56.3 0.0 5.8e-15 55.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ85882.1 - 2e-09 37.1 0.0 6e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ85882.1 - 1.6e-05 23.9 0.0 2.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase PRCH PF03967.13 CDJ85882.1 - 0.009 16.3 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Photosynthetic reaction centre, H-chain N-terminal region Kdo PF06293.14 CDJ85882.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Hint_2 PF13403.6 CDJ85882.1 - 0.049 13.9 1.0 9.6 6.5 0.0 2.9 2 1 1 3 3 3 0 Hint domain Kinase-like PF14531.6 CDJ85882.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 CDJ85883.1 - 2.1e-15 56.8 0.0 5.4e-15 55.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ85883.1 - 4.1e-08 32.8 0.2 1.1e-07 31.4 0.2 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ85883.1 - 2.5e-06 26.5 1.3 4.4e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CDJ85883.1 - 0.024 14.0 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YBD PF17725.1 CDJ85884.1 - 8.7e-73 244.6 0.4 1.1e-72 244.2 0.4 1.1 1 0 0 1 1 1 1 YAP binding domain TEA PF01285.18 CDJ85884.1 - 1.3e-25 89.2 0.0 2.7e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 TEA/ATTS domain DUF3439 PF11921.8 CDJ85885.1 - 5 7.1 10.3 9.7 6.2 10.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RT_RNaseH_2 PF17919.1 CDJ85886.1 - 4.2e-34 116.6 0.0 8e-34 115.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ85886.1 - 3.6e-31 107.6 0.0 5.8e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase L51_S25_CI-B8 PF05047.16 CDJ85886.1 - 0.032 14.1 0.0 0.094 12.7 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DNA_topoisoIV PF00521.20 CDJ85889.1 - 1.6e-126 422.7 0.0 3.1e-126 421.7 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CDJ85889.1 - 7.8e-49 165.2 8.7 7.8e-49 165.2 8.7 3.2 4 1 0 4 4 4 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CDJ85889.1 - 1.2e-27 96.5 2.1 3.9e-27 94.8 2.1 2.0 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CDJ85889.1 - 3.5e-14 53.3 0.0 8.9e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CDJ85889.1 - 1.8e-07 31.3 0.0 1e-06 28.9 0.0 2.4 1 0 0 1 1 1 1 Toprim domain PulG PF11773.8 CDJ85889.1 - 0.15 11.9 0.1 0.35 10.7 0.1 1.6 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin HemX PF04375.14 CDJ85889.1 - 0.22 10.8 6.0 0.45 9.7 6.0 1.5 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Flagellar_put PF12611.8 CDJ85889.1 - 2.1 8.2 3.9 1.5 8.7 0.5 2.4 2 0 0 2 2 2 0 Putative flagellar DEAD_2 PF06733.15 CDJ85890.1 - 6.8e-41 139.8 0.2 1.4e-40 138.8 0.2 1.6 1 0 0 1 1 1 1 DEAD_2 UCH PF00443.29 CDJ85890.1 - 7.6e-33 114.1 0.0 7.4e-32 110.8 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase OTU PF02338.19 CDJ85890.1 - 5.3e-09 36.6 0.0 1.3e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease UCH_1 PF13423.6 CDJ85890.1 - 3.7e-07 30.0 2.1 0.0014 18.3 0.7 3.5 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DEAD PF00270.29 CDJ85890.1 - 7.1e-05 22.6 0.0 0.046 13.5 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 CDJ85890.1 - 0.00079 19.5 0.1 0.4 10.7 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF5050 PF16472.5 CDJ85890.1 - 0.025 13.9 0.1 0.044 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5050) Helicase_C_2 PF13307.6 CDJ85890.1 - 0.046 13.9 0.0 0.15 12.2 0.0 1.9 2 0 0 2 2 2 0 Helicase C-terminal domain HBB PF06777.11 CDJ85890.1 - 0.089 12.5 0.0 0.27 10.9 0.0 1.8 1 0 0 1 1 1 0 Helical and beta-bridge domain Trm56 PF01994.16 CDJ85890.1 - 0.11 12.4 0.0 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 tRNA ribose 2'-O-methyltransferase, aTrm56 DUF3819 PF12842.7 CDJ85891.1 - 0.032 14.2 0.0 0.085 12.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3819) TPR_14 PF13428.6 CDJ85891.1 - 0.056 14.3 0.0 28 5.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1738 PF08401.11 CDJ85891.1 - 0.092 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1738) TPR_19 PF14559.6 CDJ85891.1 - 0.14 12.7 0.2 32 5.1 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CDJ85891.1 - 0.14 11.8 0.1 3.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_16 PF13432.6 CDJ85891.1 - 0.15 12.7 0.2 31 5.3 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat Herpes_UL52 PF03121.15 CDJ85893.1 - 3.9e-09 36.3 0.5 9.4e-09 35.1 0.5 1.6 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase Herpes_UL49_1 PF03117.14 CDJ85893.1 - 0.18 11.0 0.2 0.34 10.2 0.2 1.4 1 0 0 1 1 1 0 UL49 family TruD PF01142.18 CDJ85894.1 - 8.7e-64 215.9 0.0 1.9e-60 204.8 0.0 3.0 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) HxlR PF01638.17 CDJ85894.1 - 0.14 12.1 0.0 0.67 9.9 0.0 2.1 2 0 0 2 2 2 0 HxlR-like helix-turn-helix ubiquitin PF00240.23 CDJ85895.1 - 0.00029 20.5 0.0 0.0005 19.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 CDJ85895.1 - 0.0083 16.8 0.0 0.017 15.8 0.0 1.5 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_4 PF18036.1 CDJ85895.1 - 0.024 14.7 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain F-box PF00646.33 CDJ85895.1 - 0.055 13.4 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 F-box domain Ubiquitin_2 PF14560.6 CDJ85895.1 - 0.14 12.6 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain PP2C PF00481.21 CDJ85897.1 - 1.3e-67 228.1 1.8 9e-56 189.4 0.9 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 CDJ85897.1 - 6.6e-05 22.6 0.0 0.013 15.2 0.0 2.9 2 1 0 2 2 2 2 Protein phosphatase 2C Zn_ribbon_SprT PF17283.2 CDJ85898.1 - 0.94 9.4 3.2 0.47 10.4 0.2 2.1 2 1 0 2 2 2 0 SprT-like zinc ribbon domain zf_UBZ PF18439.1 CDJ85898.1 - 1.6 8.4 3.4 17 5.1 0.1 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Glycos_transf_2 PF00535.26 CDJ85899.1 - 9.3e-38 129.7 0.0 1.9e-37 128.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CDJ85899.1 - 7.1e-27 94.2 3.6 7.1e-27 94.2 3.6 1.6 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 CDJ85899.1 - 8.7e-08 32.3 0.0 1.4e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 CDJ85899.1 - 2e-05 24.1 0.3 6.6e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.6 CDJ85899.1 - 0.00011 22.9 0.2 0.03 15.1 0.1 2.4 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like RVT_1 PF00078.27 CDJ85899.1 - 0.0029 17.1 0.0 0.0057 16.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_tranf_2_2 PF10111.9 CDJ85899.1 - 0.071 12.6 0.0 0.2 11.1 0.0 1.8 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Galactosyl_T PF01762.21 CDJ85901.1 - 6.3e-10 39.2 0.3 1.1e-06 28.7 0.9 2.3 2 0 0 2 2 2 2 Galactosyltransferase Fringe PF02434.16 CDJ85901.1 - 1.1e-06 28.3 0.5 1.2e-05 24.9 0.5 2.2 1 1 0 1 1 1 1 Fringe-like DUF1236 PF06823.12 CDJ85901.1 - 0.18 11.7 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1236) Ground-like PF04155.18 CDJ85902.1 - 7.5e-17 61.8 0.9 7.5e-17 61.8 0.9 3.9 3 0 0 3 3 3 1 Ground-like domain PDZ PF00595.24 CDJ85902.1 - 0.099 13.0 1.6 16 5.9 0.2 2.8 2 0 0 2 2 2 0 PDZ domain Lant_dehydr_C PF14028.6 CDJ85902.1 - 0.86 9.1 5.7 1.8 8.1 5.7 1.5 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term 7TM_GPCR_Srh PF10318.9 CDJ85904.1 - 9e-23 80.8 12.3 1.4e-22 80.1 12.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Sri PF10327.9 CDJ85904.1 - 5.7e-11 42.1 11.9 8.3e-11 41.6 11.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri 7TM_GPCR_Srj PF10319.9 CDJ85904.1 - 3.8e-06 26.5 6.2 5.8e-06 25.9 6.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Str PF10326.9 CDJ85904.1 - 3.2e-05 23.4 9.3 5.1e-05 22.8 9.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str DNA_ligase_A_N PF04675.14 CDJ85904.1 - 0.00043 20.6 2.6 0.021 15.2 0.1 2.7 2 0 0 2 2 2 1 DNA ligase N terminus 7TM_GPCR_Srh PF10318.9 CDJ85905.1 - 8e-27 94.1 10.1 9.5e-27 93.8 10.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Sri PF10327.9 CDJ85905.1 - 2.4e-11 43.4 9.2 3.1e-11 43.0 9.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri 7TM_GPCR_Str PF10326.9 CDJ85905.1 - 2.1e-05 24.0 12.4 2.8e-05 23.6 12.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srj PF10319.9 CDJ85905.1 - 0.00069 19.1 8.4 0.0021 17.4 8.3 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj DUF2070 PF09843.9 CDJ85905.1 - 0.49 8.6 8.1 0.15 10.3 3.8 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) DUF3671 PF12420.8 CDJ85905.1 - 2 8.5 10.3 1.5 8.9 1.9 2.5 1 1 1 2 2 2 0 Protein of unknown function FtsX PF02687.21 CDJ85905.1 - 3.3 8.2 8.0 0.96 10.0 0.3 2.7 3 0 0 3 3 3 0 FtsX-like permease family Metal_resist PF13801.6 CDJ85906.1 - 0.14 12.3 0.4 0.27 11.4 0.4 1.5 1 0 0 1 1 1 0 Heavy-metal resistance eIF_4EBP PF05456.11 CDJ85910.1 - 0.02 14.8 0.1 0.02 14.8 0.1 2.5 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) cEGF PF12662.7 CDJ85910.1 - 0.26 11.3 0.2 0.26 11.3 0.2 2.0 3 0 0 3 3 3 0 Complement Clr-like EGF-like THAP PF05485.12 CDJ85911.1 - 0.0016 19.3 0.0 0.0041 18.0 0.0 1.8 1 0 0 1 1 1 1 THAP domain zf-C2H2_2 PF12756.7 CDJ85911.1 - 1.2 9.5 7.8 1.7 9.0 0.9 2.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF4551 PF15087.6 CDJ85911.1 - 1.9 7.2 7.6 2.5 6.8 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) zf-H2C2_2 PF13465.6 CDJ85911.1 - 4 8.0 8.6 0.15 12.6 1.3 2.6 3 0 0 3 3 3 0 Zinc-finger double domain FAM199X PF15814.5 CDJ85911.1 - 5.7 5.9 9.9 11 4.9 9.9 1.4 1 0 0 1 1 1 0 Protein family FAM199X zf-C2H2_4 PF13894.6 CDJ85911.1 - 7.2 7.7 18.5 1.6 9.8 1.0 4.2 5 0 0 5 5 5 0 C2H2-type zinc finger Collagen PF01391.18 CDJ85913.1 - 5.3e-23 80.5 114.6 6.7e-06 25.8 14.4 4.2 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ85913.1 - 3.8e-11 42.9 0.1 5.3e-11 42.4 0.1 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain RVT_1 PF00078.27 CDJ85914.1 - 2.5e-38 131.8 0.0 5e-38 130.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7TM_GPCR_Srsx PF10320.9 CDJ85916.1 - 4.1e-08 32.9 23.2 5.9e-08 32.4 23.2 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 CDJ85916.1 - 0.67 9.5 21.6 0.42 10.2 18.4 2.1 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Col_cuticle_N PF01484.17 CDJ85918.1 - 1.7e-14 53.6 1.3 2.5e-14 53.1 1.3 1.3 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ85918.1 - 1.2e-06 28.1 40.1 1.2e-06 28.1 40.1 5.2 2 1 2 4 4 4 2 Collagen triple helix repeat (20 copies) DDE_3 PF13358.6 CDJ85919.1 - 1.4e-09 37.8 0.0 1.9e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Ribosomal_L37 PF08561.10 CDJ85922.1 - 0.24 11.9 13.9 0.091 13.3 11.0 1.7 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L37 Mitovir_RNA_pol PF05919.11 CDJ85922.1 - 0.88 8.7 6.4 0.92 8.6 6.4 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase SWI-SNF_Ssr4 PF08549.10 CDJ85922.1 - 2.1 6.9 14.8 2.5 6.6 14.8 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) LCIB_C_CA PF18599.1 CDJ85922.1 - 2.8 7.2 4.4 1.3 8.3 1.5 1.8 1 1 1 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases FUSC PF04632.12 CDJ85922.1 - 4.6 5.7 5.6 4.8 5.6 5.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family PIN_8 PF18476.1 CDJ85922.1 - 5.3 6.8 13.5 9.4 6.0 13.5 1.6 1 1 0 1 1 1 0 PIN like domain Phasin PF05597.11 CDJ85922.1 - 8 6.5 15.8 3.6 7.6 2.9 2.1 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF382 PF04037.13 CDJ85923.1 - 0.032 14.4 0.1 0.86 9.8 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF382) DUF2528 PF10800.8 CDJ85923.1 - 0.036 14.6 3.8 1.1e+02 3.4 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF2528) DUF4311 PF14188.6 CDJ85923.1 - 0.068 12.9 1.8 15 5.3 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF4311) Carn_acyltransf PF00755.20 CDJ85924.1 - 1.4e-180 601.9 0.0 1.8e-180 601.5 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Pex14_N PF04695.13 CDJ85924.1 - 6.2e-10 39.9 4.4 1.4e-09 38.8 0.0 3.0 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF498 PF04430.14 CDJ85925.1 - 5.3e-25 87.6 0.0 7.9e-25 87.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Shisa PF13908.6 CDJ85926.1 - 0.029 14.6 1.4 0.061 13.6 0.0 2.2 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF3784 PF12650.7 CDJ85926.1 - 0.034 14.3 0.2 0.034 14.3 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) Connexin PF00029.19 CDJ85926.1 - 0.079 12.7 0.0 9.4 5.9 0.0 2.3 2 0 0 2 2 2 0 Connexin MARVEL PF01284.23 CDJ85926.1 - 6.3 6.8 12.5 18 5.3 7.3 2.2 1 1 1 2 2 2 0 Membrane-associating domain Nkap_C PF06047.11 CDJ85928.1 - 6.5e-40 135.4 3.7 6.5e-40 135.4 3.7 3.5 3 1 0 4 4 4 1 NF-kappa-B-activating protein C-terminal domain SR-25 PF10500.9 CDJ85928.1 - 6.2e-05 22.7 30.0 6.2e-05 22.7 30.0 4.3 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein Dicty_REP PF05086.12 CDJ85928.1 - 9.9 4.0 16.9 16 3.3 16.9 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-C2H2 PF00096.26 CDJ85929.1 - 0.0039 17.6 4.1 0.0039 17.6 4.1 2.9 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 CDJ85929.1 - 0.027 14.2 1.4 0.054 13.3 1.4 1.5 1 0 0 1 1 1 0 C2H2-type zinc-finger domain BTB PF00651.31 CDJ85929.1 - 0.061 13.6 0.4 0.11 12.7 0.0 1.6 2 0 0 2 2 2 0 BTB/POZ domain OrsD PF12013.8 CDJ85929.1 - 0.13 12.7 2.5 7.5 7.0 0.1 3.2 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_2 PF12756.7 CDJ85929.1 - 0.18 12.2 3.1 9 6.7 0.2 2.7 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CDJ85929.1 - 0.36 11.8 17.7 0.34 11.8 3.0 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger KH_10 PF17905.1 CDJ85930.1 - 2.1e-33 114.6 0.2 1e-32 112.4 0.0 2.3 2 0 0 2 2 2 1 GLD-3 KH domain 5 KH_1 PF00013.29 CDJ85930.1 - 0.00081 19.2 0.0 0.051 13.4 0.0 3.3 3 0 0 3 3 3 1 KH domain ABC_membrane PF00664.23 CDJ85933.1 - 2.1e-39 135.8 5.3 2.1e-39 135.8 5.3 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region Bac_rhodopsin PF01036.18 CDJ85933.1 - 0.95 9.0 5.6 0.1 12.1 0.5 2.0 2 1 1 3 3 3 0 Bacteriorhodopsin-like protein KELK PF15796.5 CDJ85934.1 - 0.034 14.6 0.5 0.034 14.6 0.5 3.4 4 0 0 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase STE PF02200.16 CDJ85934.1 - 0.083 13.3 0.4 0.43 11.0 0.0 2.3 2 0 0 2 2 2 0 STE like transcription factor Laminin_II PF06009.12 CDJ85934.1 - 0.47 10.5 3.8 0.78 9.8 0.1 2.7 2 1 0 2 2 2 0 Laminin Domain II RapH_N PF18801.1 CDJ85934.1 - 1.7 8.8 4.3 24 5.1 1.3 2.8 2 0 0 2 2 2 0 response regulator aspartate phosphatase H, N terminal KxDL PF10241.9 CDJ85934.1 - 2.9 8.2 6.2 13 6.1 0.1 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein FapA PF03961.13 CDJ85934.1 - 3.4 6.1 6.3 7.8 5.0 0.7 2.8 3 0 0 3 3 3 0 Flagellar Assembly Protein A CPL PF08144.11 CDJ85934.1 - 5.9 7.2 7.1 6.9 7.0 0.8 2.9 3 0 0 3 3 3 0 CPL (NUC119) domain HR1 PF02185.16 CDJ85934.1 - 6 7.1 14.2 0.078 13.1 2.1 3.4 3 0 0 3 3 3 0 Hr1 repeat zf-CCHC PF00098.23 CDJ85934.1 - 9.4 6.5 11.8 0.081 13.0 3.7 1.9 2 0 0 2 2 2 0 Zinc knuckle Mob1_phocein PF03637.17 CDJ85935.1 - 1.8e-73 246.1 0.1 2.5e-73 245.6 0.1 1.2 1 0 0 1 1 1 1 Mob1/phocein family TFIID_NTD2 PF04494.15 CDJ85935.1 - 0.14 12.4 2.7 0.078 13.2 0.8 1.5 2 0 0 2 2 2 0 WD40 associated region in TFIID subunit, NTD2 domain PHO4 PF01384.20 CDJ85936.1 - 2.3e-125 418.1 18.7 3.1e-125 417.7 18.7 1.2 1 0 0 1 1 1 1 Phosphate transporter family PAP2 PF01569.21 CDJ85936.1 - 0.033 14.0 0.0 0.033 14.0 0.0 3.3 2 1 0 3 3 3 0 PAP2 superfamily G-patch PF01585.23 CDJ85937.1 - 1.5e-16 60.0 2.6 2.8e-16 59.1 2.6 1.5 1 0 0 1 1 1 1 G-patch domain FHA PF00498.26 CDJ85937.1 - 4.2e-12 46.2 0.1 9.3e-12 45.1 0.1 1.6 1 0 0 1 1 1 1 FHA domain OCRE PF17780.1 CDJ85937.1 - 2.5e-11 43.4 12.7 4.1e-11 42.7 11.2 2.2 2 0 0 2 2 2 1 OCRE domain G-patch_2 PF12656.7 CDJ85937.1 - 9.1e-09 35.3 1.5 2.6e-08 33.8 1.5 1.8 1 0 0 1 1 1 1 G-patch domain Yop-YscD_cpl PF16697.5 CDJ85937.1 - 9.1e-06 25.9 0.0 2.2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 CDJ85937.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 FHA domain Peptidase_M20 PF01546.28 CDJ85938.1 - 1.4e-30 106.6 0.0 1.7e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CDJ85938.1 - 7.6e-13 48.3 0.0 1.3e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Guanylate_cyc PF00211.20 CDJ85939.1 - 1.5e-42 145.3 0.1 1.8e-42 145.1 0.1 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ldl_recept_a PF00057.18 CDJ85940.1 - 3.1e-18 65.7 26.0 2.1e-09 37.5 10.2 2.3 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A DUF4931 PF16285.5 CDJ85941.1 - 0.15 11.4 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4931) PSS PF03034.15 CDJ85942.1 - 9e-103 343.8 21.5 1.2e-102 343.3 21.5 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase TPP_enzyme_N PF02776.18 CDJ85944.1 - 7.6e-08 32.2 0.0 1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain FKBP_C PF00254.28 CDJ85946.1 - 3.7e-24 84.9 0.3 3.1e-23 81.9 0.3 2.0 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2149 PF09919.9 CDJ85946.1 - 0.0089 16.3 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2149) AOC_like PF18678.1 CDJ85946.1 - 0.092 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Allene oxide cyclase barrel like domain FKBP_C PF00254.28 CDJ85947.1 - 1.1e-48 163.5 0.1 2.4e-24 85.5 0.0 2.1 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2149 PF09919.9 CDJ85947.1 - 0.003 17.8 0.1 0.01 16.0 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2149) Neur_chan_LBD PF02931.23 CDJ85948.1 - 1.6e-29 102.9 0.6 3e-29 102.0 0.6 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ85948.1 - 9.5e-07 29.1 3.7 1.3e-06 28.7 1.2 2.2 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CDJ85949.1 - 1.5e-10 40.9 1.9 2.4e-10 40.3 1.9 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain ShK PF01549.24 CDJ85949.1 - 1.4e-08 35.1 9.7 2.5e-08 34.3 9.7 1.5 1 0 0 1 1 1 1 ShK domain-like Neur_chan_memb PF02932.16 CDJ85949.1 - 0.087 12.9 3.7 0.15 12.1 3.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ResIII PF04851.15 CDJ85950.1 - 9.5e-19 68.0 0.6 2.3e-17 63.5 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit RIG-I_C-RD PF11648.8 CDJ85950.1 - 5.4e-18 65.3 1.7 1.3e-17 64.1 1.7 1.6 1 0 0 1 1 1 1 C-terminal domain of RIG-I Helicase_C PF00271.31 CDJ85950.1 - 7.2e-18 65.0 1.6 8.1e-17 61.6 0.2 3.3 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ85950.1 - 3.8e-16 59.4 0.2 3e-15 56.4 0.0 2.5 2 1 1 3 3 3 1 DEAD/DEAH box helicase RIG-I_C PF18119.1 CDJ85950.1 - 0.0045 17.0 0.2 0.0045 17.0 0.2 2.4 2 1 0 2 2 2 1 RIG-I receptor C-terminal domain AAA_22 PF13401.6 CDJ85950.1 - 0.025 14.8 0.0 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CDJ85950.1 - 0.064 13.6 0.4 0.48 10.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain UvrD-helicase PF00580.21 CDJ85950.1 - 0.1 12.1 0.4 3.5 7.1 0.0 2.7 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_11 PF13086.6 CDJ85950.1 - 0.13 12.0 4.5 0.25 11.1 0.1 2.7 2 1 1 3 3 3 0 AAA domain UAA PF08449.11 CDJ85951.1 - 2e-50 171.7 7.2 2.2e-50 171.6 7.2 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 CDJ85951.1 - 0.0085 15.3 1.5 0.015 14.5 0.5 1.7 1 1 1 2 2 2 1 Nucleotide-sugar transporter CRT-like PF08627.10 CDJ85951.1 - 0.067 12.1 7.2 0.087 11.7 5.7 2.0 1 1 0 1 1 1 0 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 CDJ85951.1 - 0.23 11.6 12.3 0.056 13.6 8.4 1.9 2 0 0 2 2 2 0 EamA-like transporter family DUF2569 PF10754.9 CDJ85951.1 - 0.84 10.1 8.2 0.31 11.5 3.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) 7TMR-DISM_7TM PF07695.11 CDJ85951.1 - 1.4 8.8 12.8 2.2 8.2 12.6 1.4 1 1 0 1 1 1 0 7TM diverse intracellular signalling Ppx-GppA PF02541.16 CDJ85952.1 - 0.032 13.7 0.1 0.05 13.0 0.1 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family SelK_SelG PF10961.8 CDJ85953.1 - 3.3e-07 30.8 0.8 5.2e-07 30.2 0.8 1.5 1 1 0 1 1 1 1 Selenoprotein SelK_SelG G-alpha PF00503.20 CDJ85954.1 - 4.1e-26 92.0 0.0 1.2e-15 57.6 0.0 2.1 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.21 CDJ85954.1 - 4.3e-06 26.3 0.0 0.011 15.2 0.0 2.9 2 1 0 2 2 2 2 ADP-ribosylation factor family AAA_18 PF13238.6 CDJ85954.1 - 2e-05 25.1 0.0 3.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CDJ85954.1 - 0.0012 19.1 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDJ85954.1 - 0.0014 18.9 0.0 0.0033 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ85954.1 - 0.0023 18.3 0.0 0.003 18.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 CDJ85954.1 - 0.0034 17.1 0.0 0.0071 16.1 0.0 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 CDJ85954.1 - 0.01 15.7 0.0 0.034 13.9 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein cobW PF02492.19 CDJ85954.1 - 0.023 14.3 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 CDJ85954.1 - 0.023 14.4 0.1 0.062 13.0 0.0 1.6 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 CDJ85954.1 - 0.028 13.7 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin dNK PF01712.19 CDJ85954.1 - 0.03 14.2 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase TsaE PF02367.17 CDJ85954.1 - 0.048 13.7 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRPRB PF09439.10 CDJ85954.1 - 0.06 12.8 1.5 0.2 11.1 0.1 2.6 3 1 0 3 3 3 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 CDJ85954.1 - 0.068 13.7 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA PF00004.29 CDJ85954.1 - 0.12 12.8 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CDJ85954.1 - 0.14 11.2 0.0 8.3 5.4 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein PCRF PF03462.18 CDJ85955.1 - 1.5e-43 148.9 0.7 3.3e-43 147.8 0.7 1.6 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 CDJ85955.1 - 9.4e-32 109.4 0.8 9.4e-32 109.4 0.8 2.4 3 0 0 3 3 3 1 RF-1 domain HEPN_DZIP3 PF18738.1 CDJ85955.1 - 0.11 12.3 0.2 9.5 6.0 0.0 2.4 2 0 0 2 2 2 0 DZIP3/ hRUL138-like HEPN FAM176 PF14851.6 CDJ85957.1 - 0.033 13.8 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 FAM176 family K1 PF02960.14 CDJ85957.1 - 0.05 13.7 0.1 0.076 13.1 0.1 1.2 1 0 0 1 1 1 0 K1 glycoprotein Na_H_Exchanger PF00999.21 CDJ85958.1 - 1.8e-71 241.0 43.7 2.2e-71 240.7 43.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Bestrophin PF01062.21 CDJ85958.1 - 8.3 5.7 9.2 0.62 9.4 3.0 2.1 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel TDP43_N PF18694.1 CDJ85959.1 - 3.6e-14 52.4 0.0 1.1e-13 50.8 0.0 1.9 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain AMPK1_CBM PF16561.5 CDJ85959.1 - 2.3e-10 40.5 0.0 7.5e-10 38.9 0.0 1.9 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DUF745 PF05335.13 CDJ85959.1 - 0.0091 15.7 8.8 0.0091 15.7 8.8 4.7 3 2 2 6 6 6 1 Protein of unknown function (DUF745) TMF_DNA_bd PF12329.8 CDJ85959.1 - 0.51 10.4 0.0 0.51 10.4 0.0 6.8 4 2 1 5 5 5 0 TATA element modulatory factor 1 DNA binding MAD PF05557.13 CDJ85959.1 - 0.55 8.5 59.3 0.039 12.3 5.3 3.0 2 1 1 3 3 3 0 Mitotic checkpoint protein Tmemb_40 PF10160.9 CDJ85961.1 - 3.2e-69 233.2 16.3 3.9e-69 232.9 16.3 1.1 1 0 0 1 1 1 1 Predicted membrane protein Myb_DNA-binding PF00249.31 CDJ85962.1 - 0.00017 21.7 0.0 0.00048 20.3 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ85962.1 - 0.092 13.0 0.0 0.54 10.5 0.0 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain C1_1 PF00130.22 CDJ85962.1 - 0.25 11.3 2.8 0.63 10.0 2.8 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Phospholip_B PF04916.13 CDJ85964.1 - 3e-180 600.3 2.2 3.7e-180 600.0 2.2 1.0 1 0 0 1 1 1 1 Phospholipase B Binary_toxB_3 PF17476.2 CDJ85965.1 - 0.078 13.2 8.5 4.4 7.5 0.1 5.4 5 2 1 6 6 6 0 Clostridial binary toxin B/anthrax toxin PA domain 3 7TM_GPCR_Srsx PF10320.9 CDJ85968.1 - 3.6e-15 56.1 1.2 3.9e-15 55.9 1.2 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 CDJ85968.1 - 0.004 16.5 0.3 0.0052 16.1 0.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF1129 PF06570.11 CDJ85968.1 - 0.024 14.1 1.7 0.026 14.0 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) EMC3_TMCO1 PF01956.16 CDJ85968.1 - 0.41 10.3 6.5 2 8.1 6.5 1.9 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like TMEM141 PF15110.6 CDJ85969.1 - 0.23 12.0 0.2 0.23 12.0 0.2 1.8 2 1 0 2 2 2 0 TMEM141 protein family DUF2070 PF09843.9 CDJ85969.1 - 1.7 6.8 7.5 6.6 4.9 7.5 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) Tmem26 PF09772.9 CDJ85970.1 - 4.1e-83 279.1 12.4 2.6e-82 276.4 12.4 1.9 1 1 0 1 1 1 1 Transmembrane protein 26 Ribosomal_S27e PF01667.17 CDJ85971.1 - 1.3e-27 95.2 7.2 1.6e-27 95.0 7.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 OSCP PF00213.18 CDJ85972.1 - 5.7e-48 163.3 2.7 6.6e-48 163.1 2.7 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit COG5 PF10392.9 CDJ85972.1 - 0.0046 17.1 2.3 1.9 8.7 0.1 2.5 3 0 0 3 3 3 2 Golgi transport complex subunit 5 Dynactin PF12455.8 CDJ85972.1 - 0.022 14.0 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Dynein associated protein RNA_pol_Rpb6 PF01192.22 CDJ85973.1 - 4.3e-13 48.9 0.1 6.6e-13 48.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Utp14 PF04615.13 CDJ85974.1 - 4.6e-106 356.2 75.1 5.1e-106 356.0 75.1 1.0 1 0 0 1 1 1 1 Utp14 protein GIT1_C PF12205.8 CDJ85974.1 - 0.15 12.2 6.2 0.058 13.5 2.2 2.5 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term Proteasome PF00227.26 CDJ85975.1 - 1.4e-43 148.6 0.9 2.1e-43 148.1 0.9 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ85975.1 - 4.9e-14 51.7 0.1 1.2e-13 50.4 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF5018 PF16410.5 CDJ85975.1 - 0.0056 15.4 0.3 0.015 14.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5018) DUF2218 PF09981.9 CDJ85975.1 - 0.13 12.6 0.3 0.29 11.6 0.3 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2218) TFIIS_C PF01096.18 CDJ85976.1 - 1.6e-17 63.1 8.4 2.8e-17 62.3 2.7 2.4 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) DZR PF12773.7 CDJ85976.1 - 3.4e-05 23.8 5.7 0.016 15.3 0.5 2.4 2 0 0 2 2 2 2 Double zinc ribbon TF_Zn_Ribbon PF08271.12 CDJ85976.1 - 0.013 15.0 10.3 7 6.3 0.0 4.4 3 1 1 4 4 4 0 TFIIB zinc-binding PHD PF00628.29 CDJ85976.1 - 0.026 14.4 6.8 2 8.4 2.0 2.5 2 1 0 2 2 2 0 PHD-finger A2L_zn_ribbon PF08792.10 CDJ85976.1 - 0.026 14.3 15.5 0.87 9.4 0.2 4.2 4 1 0 4 4 4 0 A2L zinc ribbon domain Baculo_LEF5_C PF11792.8 CDJ85976.1 - 0.031 14.0 6.1 0.34 10.6 0.1 2.9 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain Rpr2 PF04032.16 CDJ85976.1 - 0.034 14.4 9.7 0.034 14.4 2.1 2.9 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain OrfB_Zn_ribbon PF07282.11 CDJ85976.1 - 0.074 13.0 7.6 0.35 10.8 0.2 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 CDJ85976.1 - 0.08 12.4 10.3 2.3 7.8 0.3 3.6 4 0 0 4 4 4 0 zinc-ribbon domain UPF0547 PF10571.9 CDJ85976.1 - 0.087 12.9 8.8 1.1 9.4 0.1 3.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-C2H2_3 PF13878.6 CDJ85976.1 - 0.11 12.4 2.0 11 5.9 0.0 3.2 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO DUF678 PF05077.12 CDJ85976.1 - 0.11 12.6 4.7 0.53 10.5 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF678) zf-RRPl_C4 PF17026.5 CDJ85976.1 - 0.31 11.1 6.6 1 9.5 6.8 1.7 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-HIT PF04438.16 CDJ85976.1 - 0.54 10.2 16.0 14 5.6 0.1 4.4 5 0 0 5 5 4 0 HIT zinc finger zinc_ribbon_2 PF13240.6 CDJ85976.1 - 0.68 9.7 12.3 3.2 7.6 0.2 3.7 4 0 0 4 4 4 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 CDJ85976.1 - 0.71 10.0 10.5 1.1 9.5 0.7 3.1 2 1 0 2 2 2 0 Zinc ribbon domain zf_UBZ PF18439.1 CDJ85976.1 - 0.72 9.5 9.8 17 5.1 0.1 4.0 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger RNA_POL_M_15KD PF02150.16 CDJ85976.1 - 0.82 9.6 7.0 3.6 7.5 0.2 3.2 2 1 1 3 3 3 0 RNA polymerases M/15 Kd subunit RNHCP PF12647.7 CDJ85976.1 - 0.83 9.7 8.1 1.9 8.5 3.7 2.6 1 1 1 2 2 2 0 RNHCP domain DNA_RNApol_7kD PF03604.13 CDJ85976.1 - 0.98 9.1 8.8 1.6 8.5 0.3 3.2 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-NADH-PPase PF09297.11 CDJ85976.1 - 1.9 8.2 7.9 3.1 7.5 0.2 3.1 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 CDJ85976.1 - 3.5 7.7 9.7 0.29 11.1 1.0 2.6 2 1 1 3 3 3 0 Transposase zinc-ribbon domain ProRS-C_1 PF09180.11 CDJ85977.1 - 1.6e-20 73.0 0.4 4.4e-20 71.7 0.4 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 CDJ85977.1 - 5.3e-18 65.0 0.0 1e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CDJ85977.1 - 1.6e-16 60.8 0.0 3.6e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 CDJ85977.1 - 1.4e-14 54.0 1.9 5.1e-14 52.2 1.9 2.0 1 0 0 1 1 1 1 WHEP-TRS domain TPR_19 PF14559.6 CDJ85978.1 - 1.2e-16 61.0 12.1 0.0018 18.7 1.9 6.7 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ85978.1 - 5.3e-15 54.8 23.9 0.12 13.2 2.4 9.9 9 2 3 12 12 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ85978.1 - 1.9e-14 52.8 7.5 0.0045 16.7 0.0 7.6 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ85978.1 - 8e-14 50.6 18.8 0.015 15.4 0.0 9.8 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ85978.1 - 5.2e-11 41.8 0.8 0.062 13.5 0.0 7.5 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ85978.1 - 7.5e-11 41.5 9.5 0.02 14.6 0.3 6.9 7 0 0 7 7 7 3 TPR repeat TPR_17 PF13431.6 CDJ85978.1 - 1.2e-09 37.8 12.4 0.56 10.7 0.0 7.8 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ85978.1 - 3.1e-08 33.8 5.7 0.82 10.0 0.1 6.2 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ85978.1 - 1.2e-06 28.8 0.6 11 7.0 0.0 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ85978.1 - 6.1e-05 22.8 1.5 1.3 9.2 0.0 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ85978.1 - 0.00029 20.6 6.8 1.7 8.6 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ85978.1 - 0.00066 20.3 18.5 0.27 11.9 0.1 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ85978.1 - 0.0011 19.0 3.6 0.23 11.7 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC5 PF12862.7 CDJ85978.1 - 0.15 12.1 2.9 27 4.9 0.4 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 ANAPC3 PF12895.7 CDJ85978.1 - 0.58 10.4 7.7 6.3 7.1 1.1 4.5 4 1 1 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 CDJ85978.1 - 4.7 7.6 8.3 3.2 8.2 0.0 3.8 3 2 1 4 4 4 0 Bacterial transcriptional activator domain Reprolysin_2 PF13574.6 CDJ85980.1 - 4.1e-15 56.2 0.1 1.3e-14 54.6 0.1 1.7 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 CDJ85980.1 - 2.6e-10 41.0 26.0 2.6e-10 41.0 26.0 3.1 3 0 0 3 3 3 1 Disintegrin Reprolysin_5 PF13688.6 CDJ85980.1 - 3e-10 40.6 3.6 3.1e-08 34.0 0.0 2.9 2 1 1 3 3 3 2 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 CDJ85980.1 - 2.7e-06 27.2 1.0 3e-05 23.8 0.1 2.2 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 CDJ85980.1 - 3.3e-06 27.6 0.3 1.7e-05 25.4 0.2 2.0 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 CDJ85980.1 - 3.7e-06 27.2 0.0 9e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 CDJ85980.1 - 0.0013 18.7 0.0 0.0013 18.7 0.0 2.6 2 1 1 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Peptidase_M43 PF05572.13 CDJ85980.1 - 0.097 12.6 0.7 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A Pyr_redox_2 PF07992.14 CDJ85981.1 - 2.7e-19 69.5 0.0 1.5e-11 44.1 0.0 2.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ85981.1 - 1.3e-05 24.2 0.1 0.0018 17.0 0.0 2.8 3 1 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 CDJ85981.1 - 0.0002 20.6 0.1 0.0024 17.0 0.0 2.3 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 CDJ85981.1 - 0.0013 18.0 0.0 0.0021 17.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 CDJ85981.1 - 0.002 18.1 0.0 2.2 8.2 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 CDJ85981.1 - 0.0085 15.7 0.0 0.37 10.3 0.0 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CDJ85981.1 - 0.0087 15.4 0.2 4.2 6.5 0.0 3.1 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CDJ85981.1 - 0.011 14.8 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 CDJ85981.1 - 0.016 15.5 0.0 0.037 14.2 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CDJ85981.1 - 0.019 14.1 0.1 1.8 7.6 0.0 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 CDJ85981.1 - 0.12 11.2 0.0 0.74 8.6 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.27 CDJ85981.1 - 0.26 11.9 1.1 11 6.7 0.2 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CDJ85982.1 - 3.4e-16 59.4 0.0 3.3e-09 36.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CDJ85982.1 - 0.00038 19.6 0.0 0.01 15.0 0.0 2.3 2 1 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 CDJ85982.1 - 0.0004 19.2 0.0 0.044 12.5 0.0 2.7 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_9 PF13454.6 CDJ85982.1 - 0.002 18.1 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 CDJ85982.1 - 0.0047 16.2 0.0 0.0083 15.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 CDJ85982.1 - 0.0056 15.6 0.0 0.39 9.5 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase DAO PF01266.24 CDJ85982.1 - 0.015 14.9 0.1 0.56 9.7 0.0 2.5 1 1 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDJ85982.1 - 0.039 14.2 0.0 0.09 13.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CDJ85982.1 - 0.082 12.2 0.3 5.4 6.2 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CDJ85982.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 CDJ85982.1 - 0.15 11.1 0.1 2.6 7.0 0.1 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A Pyr_redox PF00070.27 CDJ85982.1 - 0.17 12.5 0.2 30 5.3 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Guanylate_cyc PF00211.20 CDJ85983.1 - 1.5e-59 200.7 0.0 3.7e-59 199.4 0.0 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 CDJ85983.1 - 4.5e-36 124.7 0.1 6.2e-36 124.2 0.1 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 CDJ85983.1 - 6.5e-21 74.8 0.0 1.8e-20 73.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ85983.1 - 5.1e-16 58.8 0.0 9.7e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 CDJ85983.1 - 1.1e-05 25.0 1.1 1.8e-05 24.3 0.3 1.7 2 0 0 2 2 2 1 Heme NO binding associated Shisa PF13908.6 CDJ85983.1 - 0.027 14.7 0.2 0.05 13.8 0.2 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Glycophorin_A PF01102.18 CDJ85983.1 - 0.099 12.9 0.2 0.31 11.3 0.2 1.7 1 0 0 1 1 1 0 Glycophorin A Insulin_TMD PF17870.1 CDJ85983.1 - 1.8 8.7 6.8 0.3 11.2 2.6 1.9 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment LSR PF05624.14 CDJ85983.1 - 3.1 7.9 6.6 8.3 6.5 6.6 1.7 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) Guanylate_cyc PF00211.20 CDJ85984.1 - 1.2e-64 217.3 0.0 1.7e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 CDJ85984.1 - 1.6e-22 80.0 0.0 2.8e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ85984.1 - 1e-15 57.9 0.0 1.7e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 CDJ85984.1 - 5.8e-06 25.9 0.5 1.3e-05 24.8 0.5 1.5 1 0 0 1 1 1 1 Heme NO binding associated Shisa PF13908.6 CDJ85984.1 - 1.3e-05 25.6 0.0 2.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF1198 PF06711.11 CDJ85984.1 - 0.079 13.0 0.4 0.16 12.0 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1198) Transposase_1 PF01359.18 CDJ85984.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Transposase (partial DDE domain) WSS_VP PF12175.8 CDJ85984.1 - 0.12 11.8 0.1 0.21 11.0 0.1 1.3 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP EphA2_TM PF14575.6 CDJ85984.1 - 0.17 12.8 0.1 0.35 11.8 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ANF_receptor PF01094.28 CDJ85985.1 - 4.7e-06 25.9 0.0 5.2e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region DUF3206 PF11472.8 CDJ85985.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) SAM_PNT PF02198.16 CDJ85986.1 - 8.2e-07 28.9 0.1 1.4e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain AI-2E_transport PF01594.16 CDJ85986.1 - 0.29 10.3 0.8 0.43 9.7 0.8 1.1 1 0 0 1 1 1 0 AI-2E family transporter Fer2_3 PF13085.6 CDJ85987.1 - 6.7e-66 219.2 0.5 4.8e-32 110.2 0.0 2.4 2 0 0 2 2 2 2 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 CDJ85987.1 - 1.7e-15 57.3 28.1 4.9e-09 36.6 6.0 3.2 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 CDJ85987.1 - 2.2e-12 47.3 18.8 1.8e-07 31.5 5.0 3.8 4 2 1 5 5 5 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 CDJ85987.1 - 6.7e-12 45.3 23.9 3.6e-07 30.2 2.9 3.7 4 0 0 4 4 4 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 CDJ85987.1 - 1.1e-06 29.1 26.1 0.0056 17.2 4.2 4.8 4 0 0 4 4 4 2 4Fe-4S dicluster domain Fer2 PF00111.27 CDJ85987.1 - 7.4e-05 22.6 13.4 0.0016 18.4 0.3 3.3 3 0 0 3 3 3 2 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 CDJ85987.1 - 0.0011 19.0 27.0 0.0083 16.3 5.0 3.9 4 0 0 4 4 4 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 CDJ85987.1 - 0.0073 16.5 7.4 3.7 7.8 0.1 4.2 4 0 0 4 4 4 2 4Fe-4S dicluster domain OSTMP1 PF09777.9 CDJ85988.1 - 4e-61 206.4 12.2 5e-61 206.1 12.2 1.0 1 0 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor DUF2053 PF09767.9 CDJ85988.1 - 0.051 13.7 0.2 0.24 11.5 0.2 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2053) zf-AD PF07776.15 CDJ85988.1 - 0.06 13.6 3.4 6.7 7.0 0.1 2.7 2 1 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Flavi_NS2B PF01002.19 CDJ85990.1 - 2.1 8.2 5.5 13 5.6 0.8 2.3 2 0 0 2 2 2 0 Flavivirus non-structural protein NS2B Collagen PF01391.18 CDJ85991.1 - 1.1e-25 89.1 98.6 5.3e-10 38.9 32.4 4.2 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ85991.1 - 4e-18 65.2 0.1 6.9e-18 64.4 0.1 1.4 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Glyco_hydro_88 PF07470.13 CDJ85991.1 - 0.09 11.8 0.2 0.12 11.4 0.2 1.0 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 DNA_pol_A_exo1 PF01612.20 CDJ85992.1 - 2.3e-18 66.5 0.0 6.3e-11 42.3 0.0 2.2 2 0 0 2 2 2 2 3'-5' exonuclease Flavi_NS1 PF00948.21 CDJ85992.1 - 0.17 10.7 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Flavivirus non-structural Protein NS1 Nudix_hydro PF18290.1 CDJ85994.1 - 1.6e-20 72.9 0.2 2.6e-20 72.2 0.2 1.3 1 0 0 1 1 1 1 Nudix hydrolase domain NUDIX PF00293.28 CDJ85994.1 - 1.9e-17 63.5 0.0 3.2e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 CDJ85995.1 - 8.6e-16 58.2 0.0 1e-15 57.9 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain Collagen PF01391.18 CDJ85997.1 - 5e-24 83.8 111.9 7.5e-09 35.2 42.8 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ85997.1 - 4e-19 68.4 0.6 5.3e-19 68.0 0.6 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain VHP PF02209.19 CDJ85997.1 - 0.01 15.9 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 Villin headpiece domain Collagen PF01391.18 CDJ85998.1 - 4.1e-24 84.1 112.6 0.00025 20.7 10.2 4.2 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ85998.1 - 3.7e-19 68.5 0.4 4.9e-19 68.1 0.4 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain VHP PF02209.19 CDJ85998.1 - 0.0098 15.9 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 1 Villin headpiece domain Collagen PF01391.18 CDJ85999.1 - 6.1e-24 83.6 94.8 0.00042 20.0 6.4 4.2 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ85999.1 - 0.0015 18.5 0.3 0.002 18.1 0.3 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain VHP PF02209.19 CDJ85999.1 - 0.0079 16.3 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 1 Villin headpiece domain Collagen PF01391.18 CDJ86000.1 - 1.5e-25 88.7 100.9 5e-09 35.8 35.1 4.2 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Collagen PF01391.18 CDJ86001.1 - 5.3e-25 87.0 98.6 0.00061 19.5 6.9 4.2 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) HLH PF00010.26 CDJ86002.1 - 1.8e-08 34.2 0.1 3.6e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain LCAT PF02450.15 CDJ86003.1 - 2.9e-92 309.9 4.3 2.7e-91 306.7 4.3 1.9 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 CDJ86003.1 - 0.022 14.5 0.1 1.9 8.1 0.1 2.7 2 1 1 3 3 3 0 PGAP1-like protein Abhydrolase_1 PF00561.20 CDJ86003.1 - 0.093 12.4 0.2 0.43 10.2 0.2 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF915 PF06028.11 CDJ86003.1 - 0.11 11.8 0.2 1.3 8.3 0.1 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.8 CDJ86003.1 - 0.17 11.1 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF900 PF05990.12 CDJ86003.1 - 0.18 11.3 0.0 0.69 9.4 0.0 1.7 1 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) AAA_12 PF13087.6 CDJ86004.1 - 4.4e-52 176.6 1.1 7.6e-52 175.8 1.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ86004.1 - 1e-41 143.5 0.9 8.7e-21 74.9 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 CDJ86004.1 - 3.7e-18 65.9 0.0 2.3e-17 63.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CDJ86004.1 - 4.4e-11 43.3 0.0 1.1e-10 42.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CDJ86004.1 - 1.5e-09 38.0 0.0 0.0021 17.8 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 CDJ86004.1 - 1.8e-08 34.4 0.4 2.4e-07 30.8 0.1 2.6 2 1 0 2 2 2 1 Helicase ResIII PF04851.15 CDJ86004.1 - 2.9e-08 33.9 0.0 1.2e-07 31.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 CDJ86004.1 - 1.8e-07 31.2 0.1 1e-05 25.5 0.1 2.5 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA_16 PF13191.6 CDJ86004.1 - 3.2e-07 30.9 0.0 7.5e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDJ86004.1 - 1.1e-05 25.7 0.0 0.00018 21.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CDJ86004.1 - 0.00053 19.8 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA PF00004.29 CDJ86004.1 - 0.0027 18.1 0.2 0.05 14.0 0.2 2.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 CDJ86004.1 - 0.0036 16.5 0.0 0.0069 15.6 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase PhoH PF02562.16 CDJ86004.1 - 0.0052 16.3 0.0 0.02 14.3 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein AAA_5 PF07728.14 CDJ86004.1 - 0.0078 16.2 0.0 0.041 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 CDJ86004.1 - 0.0093 15.2 0.1 0.12 11.6 0.1 2.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 CDJ86004.1 - 0.01 15.8 0.1 1.1 9.2 0.0 2.6 2 0 0 2 2 2 0 NTPase DEAD PF00270.29 CDJ86004.1 - 0.015 15.1 0.0 0.039 13.7 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase cobW PF02492.19 CDJ86004.1 - 0.028 14.0 0.1 1.5 8.4 0.0 2.6 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 CDJ86004.1 - 0.032 13.7 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region KTI12 PF08433.10 CDJ86004.1 - 0.04 13.4 0.8 1.4 8.3 0.0 2.7 3 0 0 3 3 3 0 Chromatin associated protein KTI12 NACHT PF05729.12 CDJ86004.1 - 0.04 13.8 0.0 0.12 12.3 0.0 1.8 1 1 0 1 1 1 0 NACHT domain UvrD-helicase PF00580.21 CDJ86004.1 - 0.044 13.3 0.2 0.14 11.6 0.0 1.8 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain IstB_IS21 PF01695.17 CDJ86004.1 - 0.086 12.6 0.0 1.3 8.8 0.0 2.6 2 1 1 3 3 3 0 IstB-like ATP binding protein DUF3768 PF12599.8 CDJ86004.1 - 0.087 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3768) RNA_helicase PF00910.22 CDJ86004.1 - 0.12 12.8 0.0 0.39 11.1 0.0 2.0 1 0 0 1 1 1 0 RNA helicase PAF-AH_p_II PF03403.13 CDJ86005.1 - 2e-95 319.5 0.0 4.6e-95 318.3 0.0 1.5 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 CDJ86005.1 - 4.4e-08 32.4 0.0 4.7e-07 29.0 0.0 2.4 2 1 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 CDJ86005.1 - 2.5e-05 23.5 0.1 0.0025 16.9 0.0 2.4 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.8 CDJ86005.1 - 5e-05 22.7 0.7 0.085 12.1 0.0 2.5 2 1 1 3 3 3 2 Serine aminopeptidase, S33 AXE1 PF05448.12 CDJ86005.1 - 0.0073 15.0 0.0 0.096 11.3 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 CDJ86005.1 - 0.0074 15.8 0.1 0.023 14.2 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 CDJ86005.1 - 0.019 14.5 0.0 0.34 10.4 0.0 2.3 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 CDJ86005.1 - 0.08 13.5 0.2 0.17 12.5 0.1 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family mRNA_cap_C PF03919.15 CDJ86005.1 - 0.09 13.4 0.3 0.34 11.6 0.1 2.0 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain Abhydrolase_1 PF00561.20 CDJ86005.1 - 0.096 12.3 0.6 0.7 9.5 0.6 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 CDJ86005.1 - 0.11 12.3 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family EMP24_GP25L PF01105.24 CDJ86006.1 - 0.011 15.7 1.6 7.4 6.5 1.8 2.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DASH_Duo1 PF08651.10 CDJ86006.1 - 0.033 14.0 5.7 16 5.4 0.0 4.3 4 1 0 4 4 4 0 DASH complex subunit Duo1 Tropomyosin_1 PF12718.7 CDJ86006.1 - 0.058 13.5 10.9 0.19 11.9 8.4 2.4 2 0 0 2 2 2 0 Tropomyosin like Mak10 PF04112.13 CDJ86006.1 - 0.059 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase NPV_P10 PF05531.12 CDJ86006.1 - 0.069 13.6 2.2 5.1 7.6 0.5 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Prefoldin_2 PF01920.20 CDJ86006.1 - 0.07 13.1 8.6 1.5 8.8 4.0 2.9 3 0 0 3 3 2 0 Prefoldin subunit MtrG PF04210.13 CDJ86006.1 - 0.09 12.6 2.5 0.81 9.6 0.7 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF4407 PF14362.6 CDJ86006.1 - 0.092 12.1 7.6 0.19 11.1 7.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FAA_hydro_N_2 PF18288.1 CDJ86006.1 - 0.1 13.0 1.0 6.5 7.3 0.2 2.8 2 1 1 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 Baculo_PEP_C PF04513.12 CDJ86006.1 - 0.14 12.2 5.3 2.1 8.4 1.3 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5531 PF17671.1 CDJ86006.1 - 0.16 11.8 4.1 0.24 11.3 3.6 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5531) HSBP1 PF06825.12 CDJ86006.1 - 0.17 11.8 0.1 0.17 11.8 0.1 3.3 3 1 1 4 4 3 0 Heat shock factor binding protein 1 LMBR1 PF04791.16 CDJ86006.1 - 0.19 10.6 4.5 0.24 10.3 4.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Seryl_tRNA_N PF02403.22 CDJ86006.1 - 0.23 11.7 8.5 1.3 9.2 6.0 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PspA_IM30 PF04012.12 CDJ86006.1 - 0.23 11.0 11.9 0.047 13.3 4.8 2.4 3 0 0 3 3 2 0 PspA/IM30 family CLZ PF16526.5 CDJ86006.1 - 0.24 11.8 12.6 0.71 10.3 5.6 3.4 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CdvA PF18822.1 CDJ86006.1 - 0.24 11.2 10.9 4.9 7.0 5.1 3.1 3 1 0 3 3 3 0 CdvA-like coiled-coil domain DUF948 PF06103.11 CDJ86006.1 - 0.34 11.2 3.2 4.1 7.7 1.1 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4446 PF14584.6 CDJ86006.1 - 0.41 10.6 6.1 1.3 9.0 3.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF1635 PF07795.11 CDJ86006.1 - 0.47 10.3 7.8 0.2 11.5 4.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1635) ABC_tran_CTD PF16326.5 CDJ86006.1 - 0.49 10.7 11.6 9.8 6.5 6.6 2.9 2 1 0 2 2 2 0 ABC transporter C-terminal domain Fzo_mitofusin PF04799.13 CDJ86006.1 - 0.63 9.6 4.9 4.5 6.8 1.5 2.5 2 0 0 2 2 2 0 fzo-like conserved region DUF1178 PF06676.11 CDJ86006.1 - 0.66 10.3 11.0 0.054 13.9 1.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1178) DUF4298 PF14131.6 CDJ86006.1 - 1.1 9.3 4.2 9.2 6.3 1.0 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF4298) DUF2203 PF09969.9 CDJ86006.1 - 1.4 9.6 6.5 3 8.6 1.9 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) AAA_23 PF13476.6 CDJ86006.1 - 2 8.8 10.5 12 6.3 0.0 2.2 1 1 1 2 2 2 0 AAA domain HTH_WhiA PF02650.14 CDJ86006.1 - 2.1 8.7 7.4 5.8 7.3 0.1 2.4 2 0 0 2 2 2 0 WhiA C-terminal HTH domain Snapin_Pallidin PF14712.6 CDJ86006.1 - 2.2 8.8 12.3 11 6.5 4.3 3.8 4 1 1 5 5 4 0 Snapin/Pallidin Tmemb_cc2 PF10267.9 CDJ86006.1 - 2.5 7.1 11.2 0.83 8.7 4.9 2.1 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Allexi_40kDa PF05549.11 CDJ86006.1 - 3.3 7.2 7.4 3.8 6.9 3.1 2.4 1 1 1 2 2 2 0 Allexivirus 40kDa protein Matrilin_ccoil PF10393.9 CDJ86006.1 - 3.5 7.6 5.8 0.61 10.0 0.4 2.5 3 0 0 3 3 2 0 Trimeric coiled-coil oligomerisation domain of matrilin GAS PF13851.6 CDJ86006.1 - 4.3 6.6 15.7 1.9 7.8 10.4 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding XhlA PF10779.9 CDJ86006.1 - 5.6 7.2 12.7 17 5.7 5.7 3.7 3 1 1 4 4 3 0 Haemolysin XhlA DUF4140 PF13600.6 CDJ86006.1 - 5.7 7.5 11.1 8.1 7.0 0.1 3.2 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) FlaC_arch PF05377.11 CDJ86006.1 - 5.9 7.4 8.2 17 5.9 1.0 3.6 3 1 1 4 4 3 0 Flagella accessory protein C (FlaC) FlaG PF03646.15 CDJ86006.1 - 6 7.1 13.0 0.44 10.7 7.2 2.1 3 0 0 3 3 2 0 FlaG protein FliD_N PF02465.18 CDJ86006.1 - 6.9 7.4 7.5 2.7 8.7 2.1 2.9 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF2408 PF10303.9 CDJ86006.1 - 8.2 7.0 9.3 14 6.2 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DIL PF01843.19 CDJ86007.1 - 1.9e-25 89.1 0.6 5.7e-25 87.6 0.3 2.0 2 0 0 2 2 2 1 DIL domain GTP_EFTU PF00009.27 CDJ86008.1 - 4.4e-21 75.3 0.0 7.4e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CDJ86008.1 - 1.4e-06 28.6 0.0 4.2e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 ATP_bind_1 PF03029.17 CDJ86008.1 - 0.002 17.9 0.0 0.36 10.6 0.1 2.4 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 CDJ86008.1 - 0.014 15.3 0.0 0.099 12.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 CDJ86008.1 - 0.085 12.6 0.2 6 6.6 0.0 3.1 3 1 1 4 4 4 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 CDJ86008.1 - 0.16 12.0 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase MFS_1 PF07690.16 CDJ86010.1 - 6.3e-23 81.3 24.6 6.3e-23 81.3 24.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily SCVP PF17619.2 CDJ86012.1 - 1.6e-10 41.7 0.4 2.3e-10 41.2 0.4 1.2 1 0 0 1 1 1 1 Secreted clade V proteins Gp-FAR-1 PF05823.12 CDJ86013.1 - 1.2e-14 54.9 3.0 1.7e-14 54.4 3.0 1.3 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) PhoU_div PF01865.16 CDJ86013.1 - 0.042 13.2 0.1 0.26 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF47 DUF2205 PF10224.9 CDJ86013.1 - 0.045 13.7 0.1 0.25 11.3 0.0 2.3 2 1 0 2 2 2 0 Short coiled-coil protein HPPK PF01288.20 CDJ86013.1 - 0.087 13.3 0.6 1.2 9.7 0.0 2.3 2 1 0 2 2 2 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DUF108 PF01958.18 CDJ86014.1 - 1.5e-13 50.9 0.0 2.7e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF108 NAD_binding_3 PF03447.16 CDJ86014.1 - 8.3e-11 42.6 0.0 1.4e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 CDJ86014.1 - 0.0029 17.7 0.0 0.0051 16.9 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 CDJ86014.1 - 0.0052 17.6 0.1 0.011 16.6 0.0 1.7 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 CDJ86014.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 CDJ86014.1 - 0.022 15.4 0.0 0.04 14.5 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 CDJ86014.1 - 0.035 13.0 0.0 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family 2-Hacid_dh_C PF02826.19 CDJ86014.1 - 0.073 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 CDJ86014.1 - 0.081 13.2 0.0 0.17 12.2 0.0 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 CDJ86014.1 - 0.09 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Gp_dh_N PF00044.24 CDJ86014.1 - 0.14 12.5 0.0 0.42 11.0 0.0 1.8 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ShK PF01549.24 CDJ86015.1 - 6e-06 26.7 6.0 6e-06 26.7 6.0 2.8 1 1 2 3 3 3 1 ShK domain-like EGF PF00008.27 CDJ86015.1 - 7.2e-06 26.2 7.0 2.6e-05 24.4 7.0 2.0 1 0 0 1 1 1 1 EGF-like domain EGF_2 PF07974.13 CDJ86015.1 - 6.1e-05 23.3 10.5 6.1e-05 23.3 10.5 2.1 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.7 CDJ86015.1 - 0.00049 20.6 5.7 0.00049 20.6 5.7 2.5 2 0 0 2 2 2 1 Human growth factor-like EGF IFN-gamma PF00714.17 CDJ86017.1 - 0.013 15.4 0.5 0.02 14.7 0.5 1.3 1 0 0 1 1 1 0 Interferon gamma FidL_like PF15941.5 CDJ86017.1 - 0.028 14.9 0.7 0.052 14.0 0.7 1.4 1 0 0 1 1 1 0 FidL-like putative membrane protein Herpes_UL14 PF03580.14 CDJ86017.1 - 0.25 11.6 1.6 0.42 10.8 1.6 1.4 1 0 0 1 1 1 0 Herpesvirus UL14-like protein ABC_tran PF00005.27 CDJ86018.1 - 2.6e-18 66.8 0.0 4e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 CDJ86018.1 - 6.8e-11 41.9 20.2 1e-10 41.3 20.2 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 CDJ86018.1 - 0.0004 20.3 0.1 0.00093 19.1 0.0 1.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF2461 PF09365.10 CDJ86019.1 - 0.054 13.4 0.8 0.083 12.8 0.6 1.3 1 1 0 1 1 1 0 Conserved hypothetical protein (DUF2461) ISG65-75 PF11727.8 CDJ86019.1 - 0.061 12.5 2.6 0.076 12.2 2.6 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Nup54 PF13874.6 CDJ86019.1 - 0.17 12.0 3.8 0.31 11.1 3.8 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Rhodanese PF00581.20 CDJ86020.1 - 3e-26 92.0 0.0 8.9e-13 48.7 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain CSN8_PSD8_EIF3K PF10075.9 CDJ86021.1 - 9e-23 80.9 0.0 1.9e-21 76.6 0.0 2.1 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family Ank_2 PF12796.7 CDJ86022.1 - 3.2e-08 34.1 0.0 1.6e-07 31.8 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDJ86022.1 - 2.7e-07 30.4 0.0 0.0029 18.0 0.0 3.4 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 CDJ86022.1 - 5.9e-06 26.5 0.0 0.0057 17.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 CDJ86022.1 - 2.4e-05 24.8 0.0 0.00029 21.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ86022.1 - 3.7e-05 23.9 0.0 0.0041 17.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Glyco_hydro_20b PF02838.15 CDJ86022.1 - 0.00043 21.1 0.0 0.0014 19.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Pkinase_Tyr PF07714.17 CDJ86025.1 - 6.5e-53 179.7 0.0 1e-52 179.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 CDJ86025.1 - 6.6e-49 164.4 8.5 2.9e-13 50.2 0.0 6.7 2 1 3 6 6 6 6 Ankyrin repeats (3 copies) Pkinase PF00069.25 CDJ86025.1 - 2e-45 155.2 0.0 3.7e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ank PF00023.30 CDJ86025.1 - 1.7e-41 138.9 23.0 2.5e-07 30.8 0.5 10.8 11 0 0 11 11 11 8 Ankyrin repeat Ank_4 PF13637.6 CDJ86025.1 - 8e-40 134.7 7.4 2.8e-10 40.5 0.0 8.3 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ86025.1 - 4.3e-38 125.0 9.4 4.1e-05 23.6 0.0 10.7 11 0 0 11 11 10 8 Ankyrin repeat Ank_5 PF13857.6 CDJ86025.1 - 6.1e-31 106.1 12.5 6.2e-07 29.6 0.0 8.7 4 2 5 9 9 9 7 Ankyrin repeats (many copies) Kdo PF06293.14 CDJ86025.1 - 0.00044 19.7 0.0 0.00085 18.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ86025.1 - 0.0056 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CDJ86025.1 - 0.026 14.1 0.1 0.069 12.7 0.0 1.7 1 1 0 2 2 2 0 RIO1 family Kinase-like PF14531.6 CDJ86025.1 - 0.081 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Peptidase_M41 PF01434.18 CDJ86026.1 - 1e-66 224.4 2.2 2e-66 223.5 2.2 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CDJ86026.1 - 1.9e-44 151.3 0.0 4.1e-44 150.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ86026.1 - 4.5e-10 39.2 0.0 1.8e-09 37.2 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CDJ86026.1 - 1.4e-09 38.1 0.0 4.6e-09 36.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDJ86026.1 - 1.6e-05 25.3 0.2 0.00027 21.4 0.2 2.6 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 CDJ86026.1 - 3.1e-05 23.8 0.0 0.0001 22.1 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CDJ86026.1 - 0.00012 21.4 0.0 0.00034 19.9 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 CDJ86026.1 - 0.00048 20.4 0.1 0.042 14.1 0.0 2.6 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CDJ86026.1 - 0.0054 16.5 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 CDJ86026.1 - 0.0067 15.8 0.0 0.027 13.9 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CDJ86026.1 - 0.011 15.8 0.0 0.094 12.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CDJ86026.1 - 0.011 15.9 0.0 0.033 14.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.6 CDJ86026.1 - 0.011 16.1 0.0 0.064 13.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 CDJ86026.1 - 0.012 15.8 0.0 0.043 13.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 CDJ86026.1 - 0.015 15.9 0.0 0.046 14.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 CDJ86026.1 - 0.018 14.5 0.0 0.053 13.0 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 CDJ86026.1 - 0.02 15.1 0.0 0.072 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDJ86026.1 - 0.047 14.2 0.0 0.15 12.6 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 CDJ86026.1 - 0.064 12.8 0.2 0.22 11.1 0.2 1.9 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CDJ86026.1 - 0.071 12.8 0.0 0.34 10.6 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 CDJ86026.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CDJ86026.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Pkinase_Tyr PF07714.17 CDJ86027.1 - 3.6e-98 328.0 0.0 4.4e-62 209.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CDJ86027.1 - 1.3e-92 309.9 0.0 2.8e-60 203.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 CDJ86027.1 - 1.7e-07 30.4 0.0 1.9e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase SH2 PF00017.24 CDJ86027.1 - 2.2e-06 27.7 0.0 5.1e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 SH2 domain Kinase-like PF14531.6 CDJ86027.1 - 9.4e-06 25.1 0.0 9.4e-05 21.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CDJ86027.1 - 4e-05 23.1 1.2 0.00049 19.5 0.1 2.4 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ86027.1 - 0.12 12.3 0.4 0.38 10.6 0.1 2.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family CSM2 PF16834.5 CDJ86028.1 - 0.04 13.5 0.0 0.22 11.1 0.0 1.9 1 1 1 2 2 2 0 Shu complex component Csm2, DNA-binding DUF2933 PF11666.8 CDJ86028.1 - 0.64 10.1 5.5 0.59 10.2 3.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2933) UDPGT PF00201.18 CDJ86029.1 - 4.8e-38 131.2 0.9 5.8e-38 130.9 0.9 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ86029.1 - 1.9e-05 24.7 0.0 4.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain HTH_Tnp_Tc3_1 PF11427.8 CDJ86029.1 - 0.079 12.8 0.1 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 Tc3 transposase CtsR PF05848.11 CDJ86030.1 - 0.12 12.4 0.4 0.26 11.2 0.1 1.7 2 0 0 2 2 2 0 CtsR N-terminal HTH domain p450 PF00067.22 CDJ86031.1 - 1.5e-87 294.3 0.8 1.7e-87 294.1 0.8 1.0 1 0 0 1 1 1 1 Cytochrome P450 QVR PF17064.5 CDJ86032.1 - 1.3 9.3 8.7 4.1 7.7 8.7 1.8 1 1 0 1 1 1 0 Sleepless protein Activin_recp PF01064.23 CDJ86032.1 - 1.5 10.0 9.9 17 6.6 9.9 2.2 1 1 0 1 1 1 0 Activin types I and II receptor domain Mobilization_B PF17511.2 CDJ86034.1 - 0.044 14.1 0.3 0.055 13.8 0.3 1.2 1 0 0 1 1 1 0 Mobilization protein B Retrotrans_gag PF03732.17 CDJ86034.1 - 0.069 13.4 0.0 0.093 13.0 0.0 1.2 1 0 0 1 1 1 0 Retrotransposon gag protein eIF3_subunit PF08597.10 CDJ86035.1 - 0.0018 18.3 7.1 0.0021 18.0 7.1 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Na_trans_assoc PF06512.13 CDJ86035.1 - 3.9 7.7 9.9 44 4.3 8.8 1.9 1 1 1 2 2 2 0 Sodium ion transport-associated FA_hydroxylase PF04116.13 CDJ86037.1 - 5.4e-10 39.7 1.3 5.4e-10 39.7 1.3 1.4 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily AA_permease PF00324.21 CDJ86038.1 - 1.1e-55 189.2 37.9 7.3e-38 130.4 7.4 2.1 2 0 0 2 2 2 2 Amino acid permease SLC12 PF03522.15 CDJ86038.1 - 2e-37 129.3 8.2 3.5e-24 85.6 5.5 3.3 1 1 1 2 2 2 2 Solute carrier family 12 Porin_3 PF01459.22 CDJ86039.1 - 2e-64 217.7 5.3 2.2e-64 217.5 5.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin Myc_target_1 PF15179.6 CDJ86039.1 - 0.09 12.7 0.3 0.19 11.6 0.3 1.4 1 0 0 1 1 1 0 Myc target protein 1 Methyltransf_23 PF13489.6 CDJ86048.1 - 1.1e-05 25.3 0.0 1.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 CDJ86048.1 - 2.6e-05 24.0 0.0 3.6e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 CDJ86048.1 - 0.009 16.7 0.0 0.019 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ86048.1 - 0.013 15.3 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ86048.1 - 0.031 14.9 0.0 0.056 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AvrM_N PF18247.1 CDJ86048.1 - 0.099 12.6 0.0 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 Flax-rust effector AvrM N-terminal domain Kelch_1 PF01344.25 CDJ86049.1 - 3.1e-79 260.4 6.8 7.1e-13 47.9 0.4 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CDJ86049.1 - 7.4e-38 127.6 0.5 2.3e-06 27.7 0.0 6.4 2 1 4 6 6 6 6 Kelch motif Kelch_2 PF07646.15 CDJ86049.1 - 2.6e-28 96.9 2.6 0.00011 22.1 0.0 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 CDJ86049.1 - 8e-27 93.0 0.5 0.013 15.5 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ86049.1 - 7.3e-25 86.7 6.4 0.00061 20.0 0.0 7.0 7 0 0 7 7 7 6 Galactose oxidase, central domain BTB PF00651.31 CDJ86049.1 - 2.1e-18 66.5 2.7 4.3e-17 62.3 2.7 2.2 1 1 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.6 CDJ86049.1 - 1.6e-08 34.3 0.7 0.016 15.2 0.0 5.0 5 0 0 5 5 5 2 Kelch motif Glyoxal_oxid_N PF07250.11 CDJ86049.1 - 0.0013 18.0 0.3 0.0033 16.7 0.0 1.7 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1668 PF07893.13 CDJ86049.1 - 0.018 14.4 0.0 0.93 8.8 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1668) BACK PF07707.15 CDJ86049.1 - 0.021 14.9 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch Galactosyl_T PF01762.21 CDJ86050.1 - 5.1e-36 124.3 0.0 6.5e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase adh_short PF00106.25 CDJ86051.1 - 3e-23 82.3 0.7 4.1e-23 81.9 0.2 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ86051.1 - 2.5e-17 63.2 0.0 3.1e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ86051.1 - 0.00083 19.3 0.1 0.0024 17.8 0.0 1.7 1 1 1 2 2 2 1 KR domain DSPc PF00782.20 CDJ86052.1 - 2.9e-38 130.7 0.0 4.3e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 CDJ86052.1 - 0.00096 19.4 0.1 0.0028 18.0 0.0 1.7 2 0 0 2 2 2 1 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 CDJ86052.1 - 0.0011 19.1 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 CDJ86052.1 - 0.016 14.8 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase LRR_8 PF13855.6 CDJ86053.1 - 2e-56 187.6 48.1 3.2e-09 36.4 5.0 9.2 3 1 6 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 CDJ86053.1 - 6.3e-39 131.3 67.1 3.5e-07 30.4 2.1 11.4 3 3 9 14 14 14 14 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDJ86053.1 - 2.1e-11 43.7 32.4 0.00031 20.3 0.7 6.2 1 1 4 6 6 6 6 Leucine-rich repeat LRR_1 PF00560.33 CDJ86053.1 - 1.9e-09 36.7 56.1 4.4 8.2 0.0 17.7 19 1 0 19 19 19 4 Leucine Rich Repeat LRR_5 PF13306.6 CDJ86053.1 - 5.3e-07 29.7 3.2 1.2 9.1 0.0 4.8 3 2 1 4 4 4 3 BspA type Leucine rich repeat region (6 copies) DUF2322 PF10084.9 CDJ86053.1 - 0.034 14.2 1.5 1 9.4 0.0 3.3 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2322) YdiH PF15930.5 CDJ86053.1 - 0.087 13.0 0.4 2.9 8.1 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function LRR_6 PF13516.6 CDJ86053.1 - 2.3 8.5 59.6 2.7 8.3 0.4 13.2 13 0 0 13 13 13 0 Leucine Rich repeat DUF1465 PF07323.12 CDJ86055.1 - 0.031 14.1 0.2 0.034 14.0 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) SLC12 PF03522.15 CDJ86057.1 - 1.1e-36 126.8 0.0 1.5e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 Solute carrier family 12 AA_permease PF00324.21 CDJ86057.1 - 3e-15 55.8 32.7 4.4e-15 55.2 32.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CDJ86057.1 - 3e-09 36.2 35.5 4.4e-09 35.7 35.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CDJ86058.1 - 1.3e-89 301.0 32.7 1.6e-89 300.7 32.7 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 CDJ86058.1 - 2.3e-86 290.5 0.0 1.3e-58 199.1 0.0 2.1 1 1 1 2 2 2 2 Solute carrier family 12 DUF5409 PF17421.2 CDJ86058.1 - 0.25 12.1 1.8 0.7 10.7 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5409) UTP25 PF06862.12 CDJ86060.1 - 2.3e-112 376.2 1.1 3e-112 375.8 1.1 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF3105 PF11303.8 CDJ86061.1 - 2.6e-40 137.6 0.1 3.5e-40 137.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3105) HMA PF00403.26 CDJ86063.1 - 4.4e-10 39.9 2.2 6.6e-10 39.3 2.2 1.3 1 1 0 1 1 1 1 Heavy-metal-associated domain Rgp1 PF08737.10 CDJ86065.1 - 5.8e-37 127.9 0.0 4.3e-24 85.5 0.0 2.3 2 1 0 2 2 2 2 Rgp1 LSM PF01423.22 CDJ86066.1 - 8.8e-16 57.4 0.0 1.1e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CDJ86066.1 - 0.0016 18.6 0.1 0.0021 18.2 0.1 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain KH_1 PF00013.29 CDJ86067.1 - 1.5e-10 40.7 0.3 2.6e-10 40.0 0.3 1.4 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 CDJ86067.1 - 0.0053 16.6 0.3 0.0077 16.0 0.3 1.4 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 CDJ86067.1 - 0.014 15.2 0.1 0.032 14.1 0.0 1.7 2 0 0 2 2 2 0 KH domain Neur_chan_LBD PF02931.23 CDJ86068.1 - 1.2e-52 178.6 0.0 1.5e-52 178.2 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ86068.1 - 1.1e-32 114.0 7.7 1.6e-32 113.5 7.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CDJ86069.1 - 3.6e-41 141.0 0.2 5.1e-41 140.5 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ86069.1 - 9.1e-32 111.0 3.1 3.1e-28 99.5 0.7 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region PIF1 PF05970.14 CDJ86070.1 - 2.8e-24 86.0 0.0 3.7e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase Ribonuc_red_sm PF00268.21 CDJ86072.1 - 2.8e-115 384.6 5.0 3.4e-115 384.3 5.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain 7TM_GPCR_Srb PF02175.16 CDJ86073.1 - 2.2e-18 66.9 26.3 3.3e-18 66.3 26.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srb 7TM_GPCR_Srab PF10292.9 CDJ86073.1 - 6.1e-17 61.5 26.4 7.3e-17 61.3 26.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Sra PF02117.16 CDJ86073.1 - 8.6e-10 38.0 25.0 1.1e-09 37.6 25.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sra Sre PF03125.18 CDJ86073.1 - 0.00018 20.8 37.2 0.001 18.3 37.3 1.9 1 1 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor Srg PF02118.21 CDJ86073.1 - 0.54 9.9 37.2 0.87 9.2 36.5 1.6 1 1 0 1 1 1 0 Srg family chemoreceptor 7TM_GPCR_Srab PF10292.9 CDJ86074.1 - 1.3e-15 57.1 25.1 1.6e-15 56.8 25.1 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Srb PF02175.16 CDJ86074.1 - 2.4e-15 57.0 22.7 3.7e-15 56.4 22.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srb 7TM_GPCR_Sra PF02117.16 CDJ86074.1 - 6.5e-11 41.6 21.4 8.5e-11 41.3 21.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sra LBP_BPI_CETP_C PF02886.17 CDJ86076.1 - 4.6e-32 111.4 0.0 7.3e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain SNF PF00209.18 CDJ86077.1 - 6.8e-173 576.1 34.1 1e-171 572.2 34.1 2.0 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Brr6_like_C_C PF10104.9 CDJ86077.1 - 0.0063 16.3 0.2 0.023 14.5 0.2 2.0 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain PAN_3 PF08277.12 CDJ86078.1 - 0.19 11.6 3.0 0.9 9.4 0.1 2.2 2 0 0 2 2 2 0 PAN-like domain MANEC PF07502.14 CDJ86078.1 - 0.2 11.9 3.3 0.35 11.2 0.1 2.3 2 0 0 2 2 2 0 MANEC domain Abhydrolase_3 PF07859.13 CDJ86080.1 - 5.5e-55 186.5 0.0 4.4e-39 134.5 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CDJ86080.1 - 1.3e-06 28.1 0.0 0.0032 17.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 CDJ86080.1 - 0.00064 18.7 0.0 0.00097 18.1 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 CDJ86080.1 - 0.00066 18.7 0.0 0.067 12.1 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_6 PF12697.7 CDJ86080.1 - 0.0081 16.8 0.0 0.0097 16.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family NinF PF05810.12 CDJ86080.1 - 0.12 12.2 0.2 0.34 10.8 0.1 1.8 2 0 0 2 2 2 0 NinF protein Chlorophyllase2 PF12740.7 CDJ86080.1 - 0.13 11.1 0.0 0.3 10.0 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme DLH PF01738.18 CDJ86080.1 - 0.14 11.7 0.0 20 4.6 0.0 2.5 2 1 0 2 2 2 0 Dienelactone hydrolase family FH2 PF02181.23 CDJ86083.1 - 0.0089 15.2 1.7 0.0096 15.1 1.7 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain Lebercilin PF15619.6 CDJ86083.1 - 0.0089 15.7 7.8 0.011 15.4 7.8 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease XhlA PF10779.9 CDJ86083.1 - 0.098 12.9 1.8 0.16 12.2 1.7 1.5 1 1 0 1 1 1 0 Haemolysin XhlA DUF724 PF05266.14 CDJ86083.1 - 0.13 12.0 6.3 0.15 11.8 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) PsaF PF17550.2 CDJ86084.1 - 0.15 11.6 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function SH2 PF00017.24 CDJ86085.1 - 2.9e-18 65.7 1.4 5.4e-18 64.9 0.5 2.0 2 0 0 2 2 2 1 SH2 domain SH3_1 PF00018.28 CDJ86085.1 - 4.7e-12 45.3 0.1 3.3e-10 39.4 0.0 2.5 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 CDJ86085.1 - 8.8e-11 41.3 0.1 3.4e-08 33.1 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 CDJ86085.1 - 1.6e-10 40.7 0.0 1e-08 34.9 0.0 2.6 2 0 0 2 2 2 1 Variant SH3 domain C1_1 PF00130.22 CDJ86085.1 - 7.8e-08 32.1 5.6 1.4e-07 31.2 5.6 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 CDJ86085.1 - 0.00033 20.9 3.6 0.00075 19.8 3.6 1.6 1 0 0 1 1 1 1 C1 domain Zn_ribbon_17 PF17120.5 CDJ86085.1 - 0.007 16.0 1.0 0.014 15.0 1.0 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type PH_10 PF15411.6 CDJ86085.1 - 0.0076 16.5 0.6 0.11 12.7 0.5 2.6 2 1 0 2 2 2 1 Pleckstrin homology domain zf-RING-like PF08746.11 CDJ86085.1 - 0.026 14.8 2.4 0.059 13.7 2.4 1.6 1 0 0 1 1 1 0 RING-like domain START PF01852.19 CDJ86085.1 - 0.042 13.2 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 START domain IQ_SEC7_PH PF16453.5 CDJ86085.1 - 0.13 12.2 1.0 0.74 9.8 0.1 2.2 1 1 1 2 2 2 0 PH domain Desulfoferrod_N PF06397.12 CDJ86085.1 - 2.4 7.9 5.0 4.2 7.1 0.6 2.5 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Filament PF00038.21 CDJ86086.1 - 0.00055 19.6 1.2 0.00066 19.4 1.2 1.1 1 0 0 1 1 1 1 Intermediate filament protein DUF4509 PF14970.6 CDJ86086.1 - 0.011 15.7 0.6 0.012 15.5 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) AAA_22 PF13401.6 CDJ86086.1 - 0.075 13.3 0.0 0.081 13.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain Filament PF00038.21 CDJ86087.1 - 4.5e-05 23.2 9.8 0.00015 21.5 9.7 1.7 1 1 0 1 1 1 1 Intermediate filament protein RNase_3_N PF18497.1 CDJ86087.1 - 0.0075 16.5 1.9 0.011 15.9 0.6 1.8 1 1 1 2 2 2 1 Ribonuclease III N-terminal domain RNase_E_G PF10150.9 CDJ86087.1 - 0.019 14.4 3.1 0.021 14.3 3.1 1.1 1 0 0 1 1 1 0 Ribonuclease E/G family SYCE1 PF15233.6 CDJ86087.1 - 0.025 14.6 5.0 0.042 13.9 5.0 1.4 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 Phage_TAC_10 PF10963.8 CDJ86087.1 - 0.052 13.7 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone WD40_4 PF16300.5 CDJ86090.1 - 1.3e-34 117.9 0.2 6e-16 58.1 0.1 2.5 2 0 0 2 2 2 2 Type of WD40 repeat DUF1899 PF08953.11 CDJ86090.1 - 2.2e-21 75.5 0.1 5.9e-13 48.5 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1899) ANAPC4_WD40 PF12894.7 CDJ86090.1 - 1.5e-10 41.2 2.1 0.0034 17.7 0.1 4.9 3 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ86090.1 - 1.7e-05 25.5 3.5 0.65 11.0 0.1 5.5 5 0 0 5 5 5 1 WD domain, G-beta repeat Mlh1_C PF16413.5 CDJ86091.1 - 2e-48 165.1 0.0 3.4e-48 164.4 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 CDJ86091.1 - 2.9e-22 78.6 0.0 5.8e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CDJ86091.1 - 1.6e-13 50.7 0.1 3.2e-13 49.7 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDJ86091.1 - 1.2e-07 32.2 0.0 3.2e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.25 CDJ86094.1 - 1.3e-12 47.7 0.1 2.6e-12 46.7 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Fructosamin_kin PF03881.14 CDJ86094.1 - 0.011 14.9 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase Kdo PF06293.14 CDJ86094.1 - 0.055 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDJ86094.1 - 0.47 9.2 0.0 0.47 9.2 0.0 4.2 3 1 0 3 3 3 0 Fungal protein kinase ARD PF03079.14 CDJ86095.1 - 1.1e-45 155.7 0.8 1.2e-45 155.5 0.8 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 CDJ86095.1 - 2.8e-10 39.8 0.0 5.8e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 CDJ86095.1 - 0.00012 22.0 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 CDJ86095.1 - 0.0011 18.5 0.0 0.0016 18.1 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.6 CDJ86095.1 - 0.029 14.1 0.0 0.063 13.0 0.0 1.4 1 1 0 1 1 1 0 Cupin-like domain Beta-lactamase PF00144.24 CDJ86096.1 - 7.5e-67 225.9 0.0 9e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase PF00144.24 CDJ86097.1 - 1.7e-64 218.1 0.0 2e-64 217.9 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 CDJ86097.1 - 0.016 14.8 0.1 0.45 10.1 0.0 2.4 3 0 0 3 3 3 0 Beta-lactamase enzyme family Thiamine_BP PF01910.17 CDJ86097.1 - 0.041 13.8 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Thiamine-binding protein HIG_1_N PF04588.13 CDJ86098.1 - 5e-14 52.3 3.6 5.7e-13 48.9 0.9 2.4 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF1075 PF06388.11 CDJ86098.1 - 3.1e-08 33.7 0.0 6.8e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1075) DUF3429 PF11911.8 CDJ86098.1 - 0.04 14.2 0.7 14 5.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3429) DUF1075 PF06388.11 CDJ86099.1 - 1.3e-06 28.5 0.0 1.8e-06 28.0 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1075) DUF2070 PF09843.9 CDJ86099.1 - 0.039 12.3 0.0 0.048 12.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF1644 PF07800.12 CDJ86099.1 - 0.069 13.2 0.1 0.081 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) SecY PF00344.20 CDJ86099.1 - 0.14 11.4 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 SecY translocase YEATS PF03366.16 CDJ86100.1 - 3.9e-17 62.0 0.2 6.6e-17 61.3 0.2 1.3 1 0 0 1 1 1 1 YEATS family DDHD PF02862.17 CDJ86100.1 - 0.023 14.9 0.2 0.029 14.5 0.2 1.2 1 0 0 1 1 1 0 DDHD domain Zip PF02535.22 CDJ86100.1 - 0.033 13.4 1.0 0.039 13.2 1.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RNA_pol_Rpc4 PF05132.14 CDJ86100.1 - 0.18 12.2 5.2 0.27 11.7 5.2 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 RNA_polI_A34 PF08208.11 CDJ86100.1 - 0.28 11.2 17.4 0.41 10.7 17.4 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF5427 PF10310.9 CDJ86100.1 - 0.35 9.8 9.0 0.45 9.4 9.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) NPR3 PF03666.13 CDJ86100.1 - 0.55 8.9 9.7 0.69 8.6 9.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 CDJ86100.1 - 0.6 8.3 8.7 0.71 8.1 8.7 1.0 1 0 0 1 1 1 0 CDC45-like protein RPN2_C PF18004.1 CDJ86100.1 - 0.67 9.9 11.5 1.1 9.1 11.5 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Presenilin PF01080.17 CDJ86100.1 - 1.3 7.7 6.5 1.7 7.3 6.5 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CDJ86100.1 - 1.7 8.4 9.3 2.3 8.0 9.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 CDJ86100.1 - 3.1 7.8 5.9 4.2 7.3 5.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.15 CDJ86100.1 - 4.9 5.8 5.9 6.2 5.5 5.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FancD2 PF14631.6 CDJ86100.1 - 8 3.7 7.8 10 3.4 7.8 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Ion_trans PF00520.31 CDJ86101.1 - 1.6e-30 106.2 4.4 2e-30 105.8 4.4 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 CDJ86101.1 - 6.3e-15 55.0 0.0 1.6e-14 53.7 0.0 1.7 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 CDJ86101.1 - 3.7e-10 39.6 3.0 3.7e-10 39.6 3.0 1.8 2 0 0 2 2 2 1 Ion channel Tropomyosin_1 PF12718.7 CDJ86101.1 - 0.0049 17.0 0.2 0.0081 16.3 0.2 1.2 1 0 0 1 1 1 1 Tropomyosin like HalX PF08663.10 CDJ86101.1 - 0.16 12.3 0.7 0.37 11.2 0.7 1.7 1 0 0 1 1 1 0 HalX domain IRK PF01007.20 CDJ86101.1 - 0.4 10.5 5.2 0.45 10.3 0.5 2.2 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain Aa_trans PF01490.18 CDJ86105.1 - 2.4e-59 201.1 27.1 2.8e-59 200.9 27.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Myc_target_1 PF15179.6 CDJ86106.1 - 0.014 15.4 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Myc target protein 1 Casc1 PF12366.8 CDJ86106.1 - 0.019 14.5 1.6 0.022 14.3 1.6 1.0 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 EphA2_TM PF14575.6 CDJ86106.1 - 0.048 14.5 0.1 0.078 13.9 0.1 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SARAF PF06682.12 CDJ86106.1 - 0.067 12.8 0.0 0.076 12.7 0.0 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis MFP2b PF12150.8 CDJ86108.1 - 0.02 14.2 0.0 0.036 13.4 0.0 1.3 1 1 0 1 1 1 0 Cytosolic motility protein zf-nanos PF05741.13 CDJ86109.1 - 2.7e-14 53.1 8.1 4.7e-14 52.3 8.1 1.4 1 0 0 1 1 1 1 Nanos RNA binding domain FR47 PF08445.10 CDJ86111.1 - 0.00022 21.1 0.0 0.00033 20.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 CDJ86111.1 - 0.001 19.5 0.0 0.0012 19.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDJ86111.1 - 0.0016 18.6 0.0 0.0019 18.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDJ86111.1 - 0.022 14.7 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UNC-79 PF14776.6 CDJ86112.1 - 5.7e-194 645.7 1.5 8.7e-194 645.1 1.5 1.3 1 0 0 1 1 1 1 Cation-channel complex subunit UNC-79 PHD_2 PF13831.6 CDJ86112.1 - 1.4 8.6 5.7 3.4 7.3 0.5 2.8 2 0 0 2 2 2 0 PHD-finger P5CR_dimer PF14748.6 CDJ86113.1 - 4.5e-34 116.8 0.1 8.4e-34 115.9 0.1 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CDJ86113.1 - 7.1e-22 77.8 0.2 1.4e-21 76.9 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 CDJ86113.1 - 3.8e-05 23.9 0.0 6.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 CDJ86113.1 - 0.00012 22.2 0.1 0.00019 21.5 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 CDJ86113.1 - 0.00024 21.1 1.9 0.0015 18.6 1.9 2.0 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 CDJ86113.1 - 0.0016 18.1 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Semialdhyde_dh PF01118.24 CDJ86113.1 - 0.0027 18.2 0.0 0.0041 17.5 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 CDJ86113.1 - 0.0052 16.9 0.0 0.0085 16.2 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus IlvN PF07991.12 CDJ86113.1 - 0.0058 16.2 0.1 0.0085 15.7 0.1 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain OCD_Mu_crystall PF02423.15 CDJ86113.1 - 0.0083 15.1 0.0 0.073 12.0 0.0 2.1 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family PDH PF02153.17 CDJ86113.1 - 0.0093 15.0 0.2 0.014 14.4 0.2 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase YchF-GTPase_C PF06071.13 CDJ86113.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF933) GTP_EFTU_D3 PF03143.17 CDJ86114.1 - 1.3e-20 73.8 0.0 2.3e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CDJ86114.1 - 0.00016 22.0 0.0 0.0004 20.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 POC3_POC4 PF10448.9 CDJ86114.1 - 0.12 12.4 0.0 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 20S proteasome chaperone assembly proteins 3 and 4 Metallophos PF00149.28 CDJ86115.1 - 3e-22 80.1 0.8 4.4e-22 79.6 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD PF09423.10 CDJ86115.1 - 0.062 12.3 0.1 7.3 5.5 0.1 2.1 2 0 0 2 2 2 0 PhoD-like phosphatase MADF_DNA_bdg PF10545.9 CDJ86115.1 - 0.065 13.6 0.2 0.15 12.4 0.2 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myosin_head PF00063.21 CDJ86116.1 - 2.3e-198 660.6 8.8 7.7e-106 354.9 0.0 3.2 2 2 1 3 3 3 2 Myosin head (motor domain) TACC_C PF05010.14 CDJ86116.1 - 0.0013 18.6 14.2 0.0013 18.6 14.2 5.5 3 1 2 5 5 5 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal AAA_13 PF13166.6 CDJ86116.1 - 0.0017 17.1 25.1 0.0017 17.1 25.1 4.3 1 1 2 3 3 3 1 AAA domain TPR_MLP1_2 PF07926.12 CDJ86116.1 - 0.0028 17.7 25.0 0.0028 17.7 25.0 6.0 3 1 3 6 6 6 3 TPR/MLP1/MLP2-like protein DivIC PF04977.15 CDJ86116.1 - 0.074 12.8 0.0 0.074 12.8 0.0 10.1 8 1 3 11 11 11 0 Septum formation initiator RNA_helicase PF00910.22 CDJ86116.1 - 0.16 12.4 0.0 0.55 10.6 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 CDJ86116.1 - 0.2 12.0 0.0 0.2 12.0 0.0 3.8 3 2 0 3 3 3 0 AAA ATPase domain AAA_24 PF13479.6 CDJ86116.1 - 0.3 10.8 4.5 3.2 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain MOZ_SAS PF01853.18 CDJ86117.1 - 1.9e-33 115.6 0.3 3.3e-33 114.9 0.3 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CDJ86117.1 - 5.5e-14 51.5 1.3 1.1e-13 50.6 0.4 1.9 2 0 0 2 2 2 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 CDJ86117.1 - 0.13 12.7 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 CDJ86118.1 - 5.2e-08 32.7 0.0 6.6e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family RNA_pol_Rpb1_5 PF04998.17 CDJ86119.1 - 2.1e-23 83.1 0.1 2.2e-23 83.1 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 Nop14 PF04147.12 CDJ86119.1 - 6.7 4.8 17.6 7.5 4.6 17.6 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CDJ86119.1 - 10 4.3 15.4 12 4.1 15.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_transf_92 PF01697.27 CDJ86120.1 - 2e-37 129.2 0.9 2.9e-37 128.8 0.9 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 CDJ86120.1 - 0.0047 17.4 0.0 0.014 15.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 2 FCH PF00611.23 CDJ86121.1 - 5e-07 29.9 0.6 5e-07 29.9 0.6 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Baculo_11_kDa PF06143.11 CDJ86121.1 - 0.013 15.0 0.1 0.033 13.8 0.1 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family XPC-binding PF09280.11 CDJ86121.1 - 0.018 14.8 0.0 0.018 14.8 0.0 2.1 3 0 0 3 3 3 0 XPC-binding domain HhH-GPD PF00730.25 CDJ86121.1 - 0.029 14.8 1.1 1.4 9.4 0.3 2.9 2 2 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein Glutaredoxin2_C PF04399.13 CDJ86121.1 - 0.043 13.7 2.1 0.11 12.4 0.2 2.5 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain Baculo_PEP_C PF04513.12 CDJ86121.1 - 0.16 12.0 9.1 0.34 10.9 0.1 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF802 PF05650.11 CDJ86121.1 - 0.72 10.4 8.1 12 6.5 0.0 4.1 4 1 0 4 4 4 0 Domain of unknown function (DUF802) Cytochrom_B562 PF07361.11 CDJ86121.1 - 0.76 10.5 6.2 0.38 11.4 0.2 2.9 3 0 0 3 3 3 0 Cytochrome b562 Exonuc_VII_L PF02601.15 CDJ86121.1 - 8.7 5.8 18.4 94 2.4 18.1 2.2 1 1 0 1 1 1 0 Exonuclease VII, large subunit UAA PF08449.11 CDJ86122.1 - 9.3e-50 169.5 7.3 1e-49 169.4 7.3 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 CDJ86122.1 - 5.6e-06 25.9 2.2 6.1e-06 25.8 2.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CDJ86122.1 - 0.0006 20.0 11.4 0.00085 19.5 11.4 1.2 1 0 0 1 1 1 1 EamA-like transporter family Arv1 PF04161.13 CDJ86122.1 - 0.69 10.0 5.6 0.88 9.7 5.6 1.2 1 0 0 1 1 1 0 Arv1-like family Glyco_hydro_31 PF01055.26 CDJ86124.1 - 1.2e-130 436.7 2.5 1.6e-130 436.2 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 CDJ86124.1 - 2.4e-15 56.7 0.1 6.8e-15 55.3 0.1 1.7 2 0 0 2 2 2 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 CDJ86124.1 - 5e-10 39.1 1.3 5e-10 39.1 1.3 1.8 2 0 0 2 2 2 1 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.6 CDJ86124.1 - 1.3e-07 31.8 0.1 4e-07 30.2 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like adh_short PF00106.25 CDJ86125.1 - 1.8e-39 135.2 0.0 2.2e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ86125.1 - 1.4e-26 93.5 0.0 1.8e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ86125.1 - 9.6e-13 48.4 0.0 1.6e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CDJ86125.1 - 0.0035 16.5 0.0 0.0044 16.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.18 CDJ86125.1 - 0.0068 16.7 0.1 0.011 15.9 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 CDJ86125.1 - 0.067 13.5 0.1 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 CDJ86125.1 - 0.12 11.8 0.1 0.25 10.8 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family RAP1 PF07218.11 CDJ86126.1 - 0.71 8.1 2.8 0.95 7.7 2.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF724 PF05266.14 CDJ86127.1 - 0.044 13.6 6.3 0.081 12.7 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF755 PF05501.11 CDJ86127.1 - 0.79 10.0 5.9 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF755) GDP_Man_Dehyd PF16363.5 CDJ86128.1 - 2.2e-44 152.2 0.0 1.1e-43 149.9 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CDJ86128.1 - 6.5e-40 137.1 0.0 2.1e-39 135.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CDJ86128.1 - 4.1e-10 39.3 0.0 4.3e-09 35.9 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 CDJ86128.1 - 5e-08 32.4 0.1 0.071 12.3 0.1 3.2 2 1 0 3 3 3 3 Male sterility protein 3Beta_HSD PF01073.19 CDJ86128.1 - 1.7e-07 30.5 0.0 5e-06 25.7 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CDJ86128.1 - 2.6e-06 26.8 0.0 1e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 CDJ86128.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 CDJ86128.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.25 CDJ86128.1 - 0.21 11.0 0.0 0.42 10.0 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.10 CDJ86128.1 - 0.24 11.3 0.0 0.4 10.6 0.0 1.3 1 0 0 1 1 1 0 KR domain AAA PF00004.29 CDJ86129.1 - 1.4e-44 151.7 0.0 1.4e-40 138.7 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) SF3A2 PF16835.5 CDJ86129.1 - 3.5e-38 129.8 0.2 1e-37 128.4 0.2 1.9 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) Bromodomain PF00439.25 CDJ86129.1 - 1.3e-16 60.5 0.1 2.8e-16 59.3 0.1 1.6 1 0 0 1 1 1 1 Bromodomain AAA_lid_3 PF17862.1 CDJ86129.1 - 8.1e-10 38.4 0.2 3.4e-09 36.4 0.0 2.2 2 0 0 2 2 2 1 AAA+ lid domain zf-met PF12874.7 CDJ86129.1 - 1.8e-06 28.2 2.0 3.6e-06 27.2 2.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type IstB_IS21 PF01695.17 CDJ86129.1 - 2.7e-06 27.2 0.0 5.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 CDJ86129.1 - 2.9e-05 24.3 0.0 7.6e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CDJ86129.1 - 0.00012 22.5 0.0 0.0011 19.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain CactinC_cactus PF09732.9 CDJ86129.1 - 0.0018 18.2 0.3 0.0048 16.8 0.3 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein RNA_helicase PF00910.22 CDJ86129.1 - 0.0026 18.1 0.0 0.008 16.6 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.14 CDJ86129.1 - 0.0042 17.1 0.0 0.016 15.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 CDJ86129.1 - 0.013 15.8 0.0 0.13 12.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CDJ86129.1 - 0.02 15.4 0.3 0.1 13.2 0.0 2.4 2 0 0 2 2 1 0 AAA domain AAA_22 PF13401.6 CDJ86129.1 - 0.025 14.9 0.1 0.24 11.7 0.1 2.7 2 1 0 2 2 1 0 AAA domain RuvB_N PF05496.12 CDJ86129.1 - 0.029 14.1 0.0 0.072 12.8 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 CDJ86129.1 - 0.085 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CDJ86129.1 - 0.087 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.21 CDJ86129.1 - 0.11 11.9 0.1 0.29 10.5 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 CDJ86129.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 CDJ86129.1 - 0.2 11.2 0.0 0.46 10.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RRM_1 PF00076.22 CDJ86130.1 - 1.7e-24 85.4 0.1 5.5e-12 45.3 0.0 4.1 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ86130.1 - 2.4e-06 27.6 0.1 0.1 12.7 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif ShK PF01549.24 CDJ86131.1 - 0.00014 22.3 5.2 0.00014 22.3 5.2 1.6 2 0 0 2 2 2 1 ShK domain-like Ground-like PF04155.18 CDJ86133.1 - 6.6e-18 65.1 0.0 8.1e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Ground-like domain FOLN PF09289.10 CDJ86133.1 - 0.85 9.9 4.8 0.58 10.4 1.5 2.1 2 0 0 2 2 2 0 Follistatin/Osteonectin-like EGF domain zf-BED PF02892.15 CDJ86135.1 - 0.62 10.1 2.9 1.4 9.0 0.5 2.4 2 0 0 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 CDJ86135.1 - 2.6 8.6 9.0 14 6.4 0.2 4.1 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_12 PF18658.1 CDJ86135.1 - 4 7.1 5.9 8.6 6.0 0.3 2.3 1 1 1 2 2 2 0 Zinc-finger C2H2-type CUB PF00431.20 CDJ86136.1 - 2.6e-16 59.9 0.1 5.7e-16 58.8 0.1 1.6 1 0 0 1 1 1 1 CUB domain DHquinase_I PF01487.15 CDJ86136.1 - 0.00071 19.9 0.0 0.0012 19.1 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Lipase_2 PF01674.18 CDJ86137.1 - 1.8e-75 253.2 0.0 2.1e-75 253.0 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 2) Abhydrolase_6 PF12697.7 CDJ86137.1 - 0.00075 20.2 0.1 0.00086 20.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 CDJ86137.1 - 0.0085 15.8 0.5 0.059 13.1 0.5 2.0 1 1 0 1 1 1 1 PGAP1-like protein DUF900 PF05990.12 CDJ86137.1 - 0.019 14.5 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.15 CDJ86137.1 - 0.089 11.9 0.0 0.22 10.7 0.0 1.5 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase RMMBL PF07521.12 CDJ86137.1 - 0.19 11.7 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain OFeT_1 PF16955.5 CDJ86140.1 - 0.0063 16.2 0.4 0.0074 16.0 0.4 1.0 1 0 0 1 1 1 1 Ferrous iron uptake permease, iron-lead transporter Pex24p PF06398.11 CDJ86140.1 - 0.1 11.6 0.1 0.11 11.5 0.1 1.0 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin TM_helix PF05552.12 CDJ86140.1 - 2.2 8.4 5.5 0.4 10.7 1.5 1.8 2 0 0 2 2 2 0 Conserved TM helix DUF1456 PF07308.13 CDJ86141.1 - 0.037 14.4 2.0 0.22 11.9 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1456) LPP PF04728.13 CDJ86141.1 - 0.037 14.4 4.1 0.058 13.8 4.1 1.4 1 0 0 1 1 1 0 Lipoprotein leucine-zipper TIMELESS PF04821.14 CDJ86141.1 - 0.19 11.0 5.0 0.19 11.0 5.0 1.0 1 0 0 1 1 1 0 Timeless protein YabA PF06156.13 CDJ86141.1 - 0.96 10.1 5.4 0.98 10.1 5.4 1.0 1 0 0 1 1 1 0 Initiation control protein YabA Metallophos PF00149.28 CDJ86142.1 - 1.6e-09 38.6 2.6 2.8e-09 37.8 2.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TMIE PF16038.5 CDJ86143.1 - 0.0046 16.8 0.1 0.0055 16.5 0.1 1.1 1 0 0 1 1 1 1 TMIE protein DUF4572 PF15139.6 CDJ86143.1 - 0.066 13.1 0.0 0.078 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4572) Methyltransf_10 PF05971.12 CDJ86144.1 - 3.6e-73 246.5 0.0 4.5e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 CDJ86144.1 - 3.1e-06 26.8 0.0 6.7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Ge1_WD40 PF16529.5 CDJ86144.1 - 0.0019 17.2 0.0 0.0031 16.5 0.0 1.2 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PrmA PF06325.13 CDJ86144.1 - 0.097 12.0 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ATP_bind_1 PF03029.17 CDJ86145.1 - 3.2e-75 253.0 0.0 4.8e-75 252.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 CDJ86145.1 - 1.7e-05 24.9 0.0 0.00039 20.5 0.0 2.9 3 1 0 3 3 3 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 CDJ86145.1 - 0.013 15.9 0.0 0.027 14.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase T2SSE PF00437.20 CDJ86145.1 - 0.014 14.5 0.0 0.033 13.3 0.0 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 CDJ86145.1 - 0.017 15.5 0.0 0.038 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Ploopntkinase3 PF18751.1 CDJ86145.1 - 0.019 14.9 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_18 PF13238.6 CDJ86145.1 - 0.02 15.4 0.1 0.065 13.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CDJ86145.1 - 0.021 15.1 0.0 0.051 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CDJ86145.1 - 0.023 14.4 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain GTP_EFTU PF00009.27 CDJ86145.1 - 0.028 13.9 0.0 0.22 11.0 0.0 2.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 CDJ86145.1 - 0.029 14.5 0.0 0.069 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CDJ86145.1 - 0.033 14.6 0.0 0.086 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CDJ86145.1 - 0.081 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AP_endonuc_2 PF01261.24 CDJ86145.1 - 0.082 12.3 0.0 1.7 8.1 0.1 2.7 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel AAA_29 PF13555.6 CDJ86145.1 - 0.082 12.7 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CLP1_P PF16575.5 CDJ86145.1 - 0.09 12.6 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop FtsK_SpoIIIE PF01580.18 CDJ86145.1 - 0.091 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_5 PF07728.14 CDJ86145.1 - 0.11 12.5 0.0 3.3 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CDJ86145.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 CDJ86145.1 - 0.14 11.4 0.0 0.3 10.3 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 CDJ86145.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TetR_C_24 PF17932.1 CDJ86146.1 - 0.079 13.2 0.1 0.2 11.9 0.1 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HSP70 PF00012.20 CDJ86147.1 - 7e-262 870.0 14.9 8e-262 869.8 14.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CDJ86147.1 - 2.4e-20 72.6 1.3 1.3e-18 67.0 0.3 2.1 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CDJ86147.1 - 0.00026 21.4 5.3 0.28 11.6 0.0 3.6 3 2 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 CDJ86147.1 - 0.0056 16.0 1.6 0.081 12.2 0.1 2.8 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase FGGY_C PF02782.16 CDJ86147.1 - 0.049 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 CDJ86147.1 - 0.15 11.1 3.3 0.87 8.5 3.3 2.2 1 1 1 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Josephin PF02099.17 CDJ86148.1 - 3.2e-15 56.6 0.7 1.4e-09 38.3 0.3 3.1 1 1 1 2 2 2 2 Josephin REJ PF02010.15 CDJ86149.1 - 3.9e-19 68.8 0.2 1.2e-18 67.2 0.1 1.8 2 0 0 2 2 2 1 REJ domain JTB PF05439.12 CDJ86149.1 - 0.0017 18.4 0.1 4 7.5 0.0 2.9 2 0 0 2 2 2 2 Jumping translocation breakpoint protein (JTB) FPN1 PF06963.12 CDJ86150.1 - 4.7e-108 361.5 24.0 8.4e-107 357.4 24.0 1.9 1 1 0 1 1 1 1 Ferroportin1 (FPN1) mTERF PF02536.14 CDJ86151.1 - 2e-17 63.1 0.7 4.2e-16 58.8 0.7 2.4 1 1 0 1 1 1 1 mTERF RWD PF05773.22 CDJ86152.1 - 7.9e-18 64.8 0.2 1.8e-17 63.7 0.2 1.6 1 1 0 1 1 1 1 RWD domain UQ_con PF00179.26 CDJ86152.1 - 0.038 13.6 0.1 0.054 13.1 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme Complex1_49kDa PF00346.19 CDJ86153.1 - 4.7e-123 409.6 0.0 6e-123 409.2 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 CDJ86153.1 - 2.3e-05 23.5 0.0 6.4e-05 22.0 0.0 1.7 1 1 1 2 2 2 1 Nickel-dependent hydrogenase Cnd1 PF12717.7 CDJ86154.1 - 5.3e-20 72.1 8.8 2e-19 70.2 1.9 2.9 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 CDJ86154.1 - 6.8e-06 25.5 0.2 2.5e-05 23.6 0.1 1.9 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Adaptin_N PF01602.20 CDJ86154.1 - 0.0074 14.9 0.2 0.016 13.8 0.2 1.6 1 0 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.22 CDJ86154.1 - 0.0096 16.1 1.5 1.1 9.7 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 CDJ86154.1 - 0.052 14.0 0.0 11 6.5 0.0 3.6 2 2 1 3 3 3 0 HEAT repeats FA_desaturase PF00487.24 CDJ86155.1 - 2.2e-36 126.0 15.7 3.6e-36 125.3 15.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 CDJ86155.1 - 0.00099 19.2 0.0 0.0025 17.9 0.0 1.7 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Proteasome PF00227.26 CDJ86156.1 - 3.8e-47 160.2 0.0 4.8e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ86156.1 - 2.9e-12 46.0 0.1 6.5e-12 44.9 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Flg_hook PF02120.16 CDJ86156.1 - 0.25 11.3 1.6 20 5.2 0.1 3.0 2 1 1 3 3 3 0 Flagellar hook-length control protein FliK SH2 PF00017.24 CDJ86157.1 - 3.8e-14 52.5 0.9 5.3e-14 52.1 0.1 1.7 2 0 0 2 2 2 1 SH2 domain GldM_N PF12081.8 CDJ86157.1 - 0.021 14.9 0.8 0.05 13.7 0.6 1.6 2 0 0 2 2 2 0 GldM N-terminal domain SH2_2 PF14633.6 CDJ86157.1 - 0.19 11.1 0.0 0.19 11.1 0.0 2.1 2 0 0 2 2 2 0 SH2 domain VIR_N PF15912.5 CDJ86157.1 - 0.41 10.2 12.3 0.05 13.2 7.6 1.8 2 0 0 2 2 2 0 Virilizer, N-terminal PV-1 PF06637.11 CDJ86157.1 - 1.8 7.3 8.4 2.6 6.8 8.4 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) RR_TM4-6 PF06459.12 CDJ86157.1 - 2.5 7.8 9.9 4.8 6.9 6.3 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 XRN_M PF17846.1 CDJ86157.1 - 6.1 5.7 7.6 8.8 5.2 7.6 1.1 1 0 0 1 1 1 0 Xrn1 helical domain SIR2 PF02146.17 CDJ86158.1 - 1.4e-55 187.9 0.0 1.9e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Sir2 family HTH_24 PF13412.6 CDJ86158.1 - 0.16 11.5 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding SCVP PF17619.2 CDJ86159.1 - 2.9e-09 37.6 0.3 2.9e-09 37.6 0.3 2.3 3 0 0 3 3 3 1 Secreted clade V proteins zf-RING_2 PF13639.6 CDJ86160.1 - 4e-07 30.2 8.2 1.2e-06 28.8 8.2 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CDJ86160.1 - 4.9e-07 29.5 2.6 1.1e-06 28.4 2.6 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDJ86160.1 - 1.5e-05 25.2 7.6 3.3e-05 24.1 7.6 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CDJ86160.1 - 6.1e-05 22.9 4.6 0.00012 22.1 4.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.8 CDJ86160.1 - 0.00017 21.7 6.3 0.00036 20.6 6.3 1.5 1 1 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 CDJ86160.1 - 0.00038 20.4 5.6 0.0012 18.8 5.6 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 CDJ86160.1 - 0.00047 19.8 2.3 0.0013 18.5 2.3 1.8 1 1 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CDJ86160.1 - 0.0032 17.3 8.1 0.014 15.2 7.4 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ86160.1 - 0.005 16.8 8.5 0.0056 16.6 6.5 2.0 1 1 1 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CDJ86160.1 - 0.0075 15.9 6.8 0.016 14.8 6.8 1.7 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CDJ86160.1 - 0.0077 16.1 6.8 0.045 13.6 6.8 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Rtf2 PF04641.12 CDJ86160.1 - 0.02 14.3 1.0 0.022 14.1 1.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger RINGv PF12906.7 CDJ86160.1 - 0.025 14.7 2.8 0.055 13.6 2.8 1.6 1 1 0 1 1 1 0 RING-variant domain PHD PF00628.29 CDJ86160.1 - 0.036 13.9 3.7 0.069 13.1 3.7 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 CDJ86160.1 - 0.049 13.9 1.4 0.049 13.9 1.4 1.8 2 0 0 2 2 2 0 RING-like domain zf-C3HC4_4 PF15227.6 CDJ86160.1 - 0.13 12.5 6.2 0.13 12.4 1.1 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DUF3565 PF12088.8 CDJ86160.1 - 0.13 12.2 2.8 0.31 11.0 2.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3565) Pellino PF04710.14 CDJ86160.1 - 0.14 10.8 1.6 0.17 10.5 1.6 1.1 1 0 0 1 1 1 0 Pellino zf-RING_4 PF14570.6 CDJ86160.1 - 0.77 9.6 5.7 3.3 7.6 5.7 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain p53-inducible11 PF14936.6 CDJ86161.1 - 0.0047 17.0 0.3 0.0093 16.0 0.3 1.5 1 0 0 1 1 1 1 Tumour protein p53-inducible protein 11 Ldl_recept_a PF00057.18 CDJ86163.1 - 0.0053 16.9 1.9 0.0053 16.9 1.9 1.7 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A CUB PF00431.20 CDJ86163.1 - 0.15 12.4 0.0 1.9 8.8 0.0 2.2 2 0 0 2 2 2 0 CUB domain Smg4_UPF3 PF03467.15 CDJ86165.1 - 6.2e-35 120.8 0.1 6.2e-35 120.8 0.1 2.1 2 0 0 2 2 2 1 Smg-4/UPF3 family Helicase_C PF00271.31 CDJ86165.1 - 1.5e-15 57.5 0.1 3.8e-15 56.2 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 CDJ86165.1 - 5.6e-13 49.1 0.0 5.6e-13 49.1 0.0 3.2 3 1 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDJ86165.1 - 2.2e-08 34.3 0.0 4.8e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DUF2002 PF09400.10 CDJ86167.1 - 0.013 15.5 0.5 0.082 12.9 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2002) Nucleoside_tran PF01733.18 CDJ86168.1 - 1.1e-56 192.5 25.1 9.5e-56 189.4 20.2 2.5 2 1 0 2 2 2 1 Nucleoside transporter DUF4501 PF14946.6 CDJ86168.1 - 1.8 8.6 5.4 9.7 6.2 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4501) 2Fe-2S_thioredx PF01257.19 CDJ86169.1 - 1.6e-61 206.4 0.0 1.9e-61 206.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin UPF0020 PF01170.18 CDJ86170.1 - 1.8e-08 34.3 0.0 6e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 CDJ86170.1 - 1.2e-07 31.7 0.3 0.00019 21.2 0.0 2.3 2 0 0 2 2 2 2 DNA methylase N6_Mtase PF02384.16 CDJ86170.1 - 0.0012 18.2 0.0 0.0044 16.3 0.0 1.8 1 1 0 1 1 1 1 N-6 DNA Methylase Yip1 PF04893.17 CDJ86171.1 - 0.028 14.2 0.5 0.034 13.8 0.5 1.0 1 0 0 1 1 1 0 Yip1 domain BppL_N PF18338.1 CDJ86171.1 - 0.065 13.0 1.1 0.089 12.6 0.5 1.5 2 0 0 2 2 2 0 Lower baseplate protein N-terminal domain Vac7 PF12751.7 CDJ86172.1 - 0.0024 17.4 0.1 0.0029 17.1 0.1 1.1 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 SNARE PF05739.19 CDJ86172.1 - 0.029 14.4 1.2 0.054 13.5 1.2 1.4 1 0 0 1 1 1 0 SNARE domain XRN_N PF03159.18 CDJ86173.1 - 4e-93 311.3 0.0 6.3e-93 310.7 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CDJ86173.1 - 1.2e-91 307.9 0.5 2.2e-91 307.0 0.5 1.4 1 0 0 1 1 1 1 Xrn1 helical domain XRN1_D1 PF18332.1 CDJ86173.1 - 1.1e-22 80.8 0.0 1.9e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 CDJ86173.1 - 3.3e-16 59.1 0.2 7.1e-16 58.1 0.2 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN1_D2_D3 PF18334.1 CDJ86173.1 - 0.0022 18.1 0.0 0.0077 16.4 0.0 2.0 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain Meiosis_expr PF15163.6 CDJ86173.1 - 0.027 15.1 3.0 0.065 13.9 3.0 1.6 1 0 0 1 1 1 0 Meiosis-expressed c-SKI_SMAD_bind PF08782.10 CDJ86174.1 - 1.6e-17 63.5 0.6 2.8e-17 62.7 0.6 1.4 1 0 0 1 1 1 1 c-SKI Smad4 binding domain Ski_Sno PF02437.17 CDJ86174.1 - 3.5e-07 29.9 0.0 9.6e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 SKI/SNO/DAC family Jas PF16135.5 CDJ86174.1 - 0.022 14.9 0.3 0.043 14.0 0.3 1.5 1 0 0 1 1 1 0 TPL-binding domain in jasmonate signalling Pkinase PF00069.25 CDJ86175.1 - 7.6e-65 218.9 0.0 9.6e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ86175.1 - 1.5e-32 112.9 0.0 2.2e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.24 CDJ86175.1 - 7.6e-15 54.6 0.1 2e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 PB1 domain C1_1 PF00130.22 CDJ86175.1 - 3.4e-12 46.1 8.1 6.2e-12 45.2 8.1 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 CDJ86175.1 - 3.9e-08 33.9 2.7 8.1e-08 32.8 2.7 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CDJ86175.1 - 8.2e-05 21.7 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CDJ86175.1 - 0.0001 21.8 0.0 0.00024 20.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CDJ86175.1 - 0.0078 15.9 0.1 0.41 10.2 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CDJ86175.1 - 0.1 12.5 0.1 0.31 10.9 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family C1_2 PF03107.16 CDJ86175.1 - 0.23 11.8 7.5 0.2 12.0 5.4 2.0 2 0 0 2 2 2 0 C1 domain PHD_2 PF13831.6 CDJ86175.1 - 0.65 9.6 5.7 1.5 8.5 5.7 1.5 1 0 0 1 1 1 0 PHD-finger PDZ PF00595.24 CDJ86177.1 - 1.3e-123 403.5 30.2 2.4e-18 66.2 0.3 10.6 10 0 0 10 10 10 10 PDZ domain PDZ_6 PF17820.1 CDJ86177.1 - 8.7e-69 227.2 24.5 3.1e-09 36.5 0.2 10.5 10 0 0 10 10 10 10 PDZ domain PDZ_2 PF13180.6 CDJ86177.1 - 7.7e-42 141.5 23.0 1.7e-05 25.0 0.1 10.7 11 0 0 11 11 11 9 PDZ domain GRASP55_65 PF04495.14 CDJ86177.1 - 0.00078 19.8 0.2 12 6.2 0.0 4.0 4 0 0 4 4 4 2 GRASP55/65 PDZ-like domain Frigida PF07899.11 CDJ86177.1 - 0.023 14.0 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Frigida-like protein CAP_N PF01213.19 CDJ86178.1 - 6.1 6.2 13.0 0.93 8.9 1.9 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal ATG13 PF10033.9 CDJ86180.1 - 0.0062 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 UPF0669 PF17065.5 CDJ86181.1 - 2.5e-15 56.7 1.0 1e-14 54.7 1.0 1.8 1 1 0 1 1 1 1 Putative cytokine, C6ORF120 AAA_23 PF13476.6 CDJ86182.1 - 4.6e-17 63.2 0.1 4.6e-17 63.2 0.1 5.2 2 2 3 5 5 3 1 AAA domain SMC_N PF02463.19 CDJ86182.1 - 1.6e-15 57.1 10.0 1.3e-14 54.1 10.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain TPR_MLP1_2 PF07926.12 CDJ86182.1 - 0.00025 21.1 83.4 0.024 14.7 2.5 8.0 4 2 4 8 8 8 4 TPR/MLP1/MLP2-like protein AAA_29 PF13555.6 CDJ86182.1 - 0.073 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Baculo_PEP_C PF04513.12 CDJ86182.1 - 0.084 12.9 16.7 2.7 8.0 0.0 4.4 3 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 CDJ86182.1 - 0.085 12.9 44.3 0.66 10.0 2.1 5.8 4 1 2 6 6 6 0 Laminin Domain II AAA_21 PF13304.6 CDJ86182.1 - 0.35 10.6 13.3 0.27 11.0 0.3 3.6 3 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system T2SSM_b PF10741.9 CDJ86182.1 - 0.4 10.5 2.1 0.77 9.6 0.5 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b GAS PF13851.6 CDJ86182.1 - 0.71 9.2 75.6 0.1 11.9 17.4 6.3 3 2 1 5 5 5 0 Growth-arrest specific micro-tubule binding WEMBL PF05701.11 CDJ86182.1 - 0.93 8.1 66.0 0.25 10.0 12.2 4.4 2 1 2 4 4 4 0 Weak chloroplast movement under blue light CENP-F_leu_zip PF10473.9 CDJ86182.1 - 1.1 9.2 86.0 0.033 14.2 10.5 6.3 4 2 2 6 6 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 CDJ86182.1 - 3.1 8.2 79.6 0.63 10.5 11.1 5.8 2 2 4 6 6 6 0 Fez1 FUSC PF04632.12 CDJ86182.1 - 4.3 5.7 21.6 1.7 7.1 12.6 2.3 2 0 0 2 2 2 0 Fusaric acid resistance protein family IFT57 PF10498.9 CDJ86182.1 - 6.1 5.7 71.4 0.037 13.0 8.1 6.0 4 2 2 6 6 6 0 Intra-flagellar transport protein 57 Spc7 PF08317.11 CDJ86182.1 - 7.6 5.3 83.2 0.16 10.8 14.9 5.8 2 2 3 5 5 5 0 Spc7 kinetochore protein COesterase PF00135.28 CDJ86185.1 - 8.9e-89 298.7 6.8 1.8e-72 244.8 0.6 3.1 3 0 0 3 3 3 3 Carboxylesterase family Abhydrolase_3 PF07859.13 CDJ86185.1 - 0.0024 17.8 0.0 0.0073 16.2 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ag332 PF04671.12 CDJ86186.1 - 6.4e-16 57.8 4.9 34 4.5 0.0 18.2 22 0 0 22 22 22 1 Erythrocyte membrane-associated giant protein antigen 332 FAM92 PF06730.11 CDJ86186.1 - 3.2e-10 39.8 16.1 15 4.9 0.0 13.3 5 3 11 17 17 17 5 FAM92 protein CdiA_C PF18451.1 CDJ86186.1 - 0.074 13.3 37.0 6.1 7.1 0.5 14.1 11 5 4 18 18 18 0 Contact-dependent growth inhibition CdiA C-terminal domain Fam20C PF06702.12 CDJ86187.1 - 1e-80 270.7 0.3 2.2e-80 269.6 0.3 1.5 1 0 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 FAM198 PF15051.6 CDJ86187.1 - 9.1e-05 21.5 0.0 0.00016 20.7 0.0 1.4 1 0 0 1 1 1 1 FAM198 protein Telomerase_RBD PF12009.8 CDJ86187.1 - 0.0089 16.1 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain PI3_PI4_kinase PF00454.27 CDJ86187.1 - 0.097 12.5 1.0 1.2 8.9 0.3 2.4 1 1 1 2 2 2 0 Phosphatidylinositol 3- and 4-kinase Ras PF00071.22 CDJ86189.1 - 1.2e-49 168.0 0.0 1.4e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ86189.1 - 1.7e-18 67.0 0.1 3.3e-18 66.0 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ86189.1 - 1.8e-08 34.0 0.0 2.1e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDJ86189.1 - 2e-05 24.2 0.2 3.9e-05 23.3 0.1 1.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CDJ86189.1 - 0.00027 21.2 1.5 0.27 11.5 0.1 2.6 2 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 CDJ86189.1 - 0.00096 19.1 0.7 0.74 9.7 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CDJ86189.1 - 0.00096 19.2 0.0 0.0023 18.0 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 CDJ86189.1 - 0.025 14.3 0.0 0.041 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain ParA PF10609.9 CDJ86189.1 - 0.043 13.3 0.1 0.07 12.6 0.1 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Cation_ATPase PF13246.6 CDJ86190.1 - 0.031 14.3 0.1 0.052 13.6 0.1 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) DUF4200 PF13863.6 CDJ86190.1 - 0.044 14.2 9.2 0.099 13.1 9.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TcdB_N PF12918.7 CDJ86190.1 - 0.072 13.4 0.2 0.19 12.1 0.2 1.7 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain COMP PF11598.8 CDJ86190.1 - 0.093 13.2 1.4 0.29 11.6 1.4 1.9 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein Vir_act_alpha_C PF10400.9 CDJ86190.1 - 0.18 12.5 4.1 0.43 11.3 0.1 2.5 1 1 1 2 2 2 0 Virulence activator alpha C-term Rx_N PF18052.1 CDJ86190.1 - 0.48 10.7 5.4 1.4 9.2 2.7 2.2 1 1 1 2 2 2 0 Rx N-terminal domain Sld5 PF05916.11 CDJ86190.1 - 0.63 10.5 4.4 0.93 10.0 3.7 1.7 1 1 0 1 1 1 0 GINS complex protein CorA PF01544.18 CDJ86190.1 - 1.5 8.1 7.6 2.2 7.5 7.6 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.12 CDJ86190.1 - 1.6 8.8 6.2 4 7.5 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Neur_chan_LBD PF02931.23 CDJ86191.1 - 8.4e-44 149.6 5.6 1.4e-43 148.9 5.6 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ86191.1 - 3.9e-23 82.7 0.0 1.2e-20 74.6 0.0 2.3 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region zf-CSL PF05207.13 CDJ86193.1 - 1.2e-23 82.5 1.1 1.5e-23 82.3 1.1 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 CDJ86193.1 - 0.00048 20.2 0.5 0.00071 19.6 0.5 1.3 1 0 0 1 1 1 1 Zinc ribbon domain zinc_ribbon_4 PF13717.6 CDJ86193.1 - 0.099 12.6 0.2 0.15 12.0 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbon domain V-ATPase_H_N PF03224.14 CDJ86194.1 - 0.06 12.6 0.0 0.11 11.8 0.0 1.5 1 1 0 1 1 1 0 V-ATPase subunit H CHB_HEX PF03173.13 CDJ86194.1 - 0.15 11.7 0.0 15 5.3 0.0 2.2 1 1 1 2 2 2 0 Putative carbohydrate binding domain KAP PF05804.12 CDJ86195.1 - 1.4e-71 241.6 0.1 1.6e-71 241.5 0.1 1.0 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Cation_efflux PF01545.21 CDJ86196.1 - 2.5e-13 50.2 11.3 5.4e-13 49.1 11.3 1.5 1 1 0 1 1 1 1 Cation efflux family LRR19-TM PF15176.6 CDJ86196.1 - 0.36 10.9 2.4 0.74 9.8 0.0 2.6 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF1422 PF07226.11 CDJ86196.1 - 0.84 9.7 5.9 4.6 7.3 3.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) COQ7 PF03232.13 CDJ86197.1 - 1.8e-64 216.6 0.0 2.1e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Acetyltransf_17 PF17668.1 CDJ86197.1 - 0.0027 18.5 0.3 0.12 13.2 0.0 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Rubrerythrin PF02915.17 CDJ86197.1 - 0.037 14.4 0.1 0.11 12.9 0.0 1.8 1 1 0 1 1 1 0 Rubrerythrin C4bp_oligo PF18453.1 CDJ86198.1 - 0.028 14.6 1.2 0.11 12.8 1.2 2.0 1 1 0 1 1 1 0 Oligomerization domain of C4b-binding protein alpha NFACT-C PF11923.8 CDJ86198.1 - 0.12 12.3 0.8 0.32 10.9 0.1 2.0 2 1 0 2 2 2 0 NFACT protein C-terminal domain DUF5641 PF18701.1 CDJ86199.1 - 3.8e-20 71.8 0.0 1.5e-19 69.9 0.0 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF5641) rve_3 PF13683.6 CDJ86199.1 - 0.084 12.7 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Myosin_head PF00063.21 CDJ86201.1 - 5.2e-222 738.8 0.0 6.4e-222 738.5 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 CDJ86201.1 - 0.027 14.8 0.0 0.078 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CDJ86201.1 - 0.053 13.8 1.2 0.3 11.4 0.1 2.7 3 0 0 3 3 3 0 AAA domain Di19_C PF14571.6 CDJ86201.1 - 0.12 13.0 0.0 0.43 11.1 0.0 2.0 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal RNA_helicase PF00910.22 CDJ86201.1 - 0.13 12.7 0.2 0.67 10.4 0.0 2.3 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 CDJ86201.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 NTPase DB PF01682.19 CDJ86202.1 - 6.3e-24 84.2 12.7 1.1e-23 83.4 12.7 1.4 1 0 0 1 1 1 1 DB module DUF974 PF06159.13 CDJ86203.1 - 3.7e-68 230.0 0.0 6.4e-68 229.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF974) NAC PF01849.18 CDJ86204.1 - 4.6e-23 80.9 0.5 9.6e-23 79.9 0.5 1.6 1 0 0 1 1 1 1 NAC domain IMS_HHH PF11798.8 CDJ86204.1 - 0.093 13.1 0.2 0.51 10.8 0.0 2.4 3 0 0 3 3 3 0 IMS family HHH motif Snf7 PF03357.21 CDJ86205.1 - 9e-49 165.4 13.1 1.1e-48 165.1 13.1 1.1 1 0 0 1 1 1 1 Snf7 Ribosomal_L22 PF00237.19 CDJ86205.1 - 0.32 11.2 2.8 3 8.1 0.1 2.9 1 1 2 3 3 3 0 Ribosomal protein L22p/L17e Herpes_UL6 PF01763.16 CDJ86205.1 - 5.3 5.4 7.3 15 3.9 7.3 1.6 1 1 0 1 1 1 0 Herpesvirus UL6 like EF-hand_1 PF00036.32 CDJ86206.1 - 4.5e-25 85.3 12.8 0.0016 17.9 0.1 6.7 6 0 0 6 6 6 6 EF hand EF-hand_7 PF13499.6 CDJ86206.1 - 7.7e-25 87.1 9.8 7.5e-10 39.1 0.3 3.8 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CDJ86206.1 - 2e-21 74.0 4.5 0.012 15.5 0.0 6.5 6 0 0 6 6 6 6 EF-hand domain EF-hand_5 PF13202.6 CDJ86206.1 - 2.6e-21 74.1 17.1 0.00013 21.3 0.0 6.8 7 0 0 7 7 7 5 EF hand EF-hand_8 PF13833.6 CDJ86206.1 - 1.2e-12 47.4 6.7 0.048 13.5 0.0 5.7 6 0 0 6 6 6 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ86206.1 - 1.2e-10 41.7 2.6 8e-05 22.9 0.1 3.8 3 1 1 4 4 4 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 CDJ86206.1 - 0.072 13.0 0.2 11 5.9 0.1 3.1 3 0 0 3 3 3 0 EF hand DUF1707 PF08044.11 CDJ86206.1 - 0.12 12.5 1.1 21 5.3 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1707) Dockerin_1 PF00404.18 CDJ86206.1 - 0.28 11.4 11.4 22 5.3 0.0 5.0 4 2 2 6 6 6 0 Dockerin type I domain TPR_2 PF07719.17 CDJ86207.1 - 8e-10 38.1 6.0 0.002 18.1 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ86207.1 - 1.8e-06 27.5 4.4 0.014 15.2 0.1 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ86207.1 - 4.2e-06 27.2 6.3 8.2e-05 23.0 0.5 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ86207.1 - 1.6e-05 24.5 3.0 0.012 15.2 0.3 3.4 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.6 CDJ86207.1 - 5.3e-05 23.7 0.2 0.073 13.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ86207.1 - 0.00015 21.7 2.5 0.027 14.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 CDJ86207.1 - 0.00081 19.8 1.6 0.0014 19.1 1.6 1.4 1 0 0 1 1 1 1 Bacterial transcriptional activator domain TPR_12 PF13424.6 CDJ86207.1 - 0.0025 18.1 1.9 1.5 9.1 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ86207.1 - 0.0029 17.8 1.1 0.13 12.5 0.5 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CDJ86207.1 - 0.017 15.7 1.2 7.7 7.3 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ86207.1 - 0.019 15.3 1.0 6.8 7.3 0.2 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 CDJ86207.1 - 0.033 14.3 0.1 0.11 12.6 0.1 1.9 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain CDV3 PF15359.6 CDJ86207.1 - 0.088 13.3 0.4 0.17 12.3 0.4 1.5 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 TPR_6 PF13174.6 CDJ86207.1 - 0.13 13.0 1.2 9.3 7.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.31 CDJ86208.1 - 2.3e-22 78.9 0.6 2.3e-22 78.9 0.6 2.1 2 0 0 2 2 2 1 DnaJ domain Thioredoxin PF00085.20 CDJ86208.1 - 0.0081 16.1 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Proton_antipo_N PF00662.20 CDJ86208.1 - 0.15 12.1 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus DnaJ PF00226.31 CDJ86209.1 - 5.7e-23 80.8 0.6 1e-22 80.0 0.6 1.4 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 CDJ86209.1 - 0.0033 17.4 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin DUF1232 PF06803.12 CDJ86211.1 - 1.7e-08 34.1 8.8 4.6e-08 32.7 8.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1232) zf-RING_UBOX PF13445.6 CDJ86211.1 - 4.8e-07 29.7 10.1 9.4e-07 28.8 10.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDJ86211.1 - 1.6e-06 27.8 5.3 1.6e-06 27.8 5.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ86211.1 - 1.7e-06 27.8 10.1 3.5e-06 26.8 10.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ86211.1 - 1e-05 25.2 9.2 1.6e-05 24.6 9.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ86211.1 - 1.2e-05 25.6 12.5 1.8e-05 24.9 12.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 CDJ86211.1 - 1.3e-05 25.2 12.2 2.4e-05 24.4 12.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CDJ86211.1 - 0.00011 22.1 10.9 0.00021 21.2 10.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDJ86211.1 - 0.015 15.1 10.9 0.077 12.9 11.2 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Eapp_C PF10238.9 CDJ86211.1 - 0.35 10.9 3.5 2.5 8.2 0.2 2.2 1 1 0 2 2 2 0 E2F-associated phosphoprotein Baculo_IE-1 PF05290.11 CDJ86211.1 - 2.2 8.2 6.7 4.1 7.4 6.7 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) LRR_8 PF13855.6 CDJ86212.1 - 3.5e-18 65.1 21.2 6.7e-10 38.6 4.8 4.3 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CDJ86212.1 - 2.7e-17 62.6 24.6 5.3e-07 29.9 1.4 5.2 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CDJ86212.1 - 0.00016 21.4 17.8 3.2 8.0 0.2 6.8 7 0 0 7 7 7 2 Leucine Rich repeat LRR_9 PF14580.6 CDJ86212.1 - 0.00078 19.0 9.0 0.018 14.5 1.1 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 CDJ86212.1 - 0.058 14.0 24.1 6.2 7.8 0.5 7.5 8 1 0 8 8 8 0 Leucine Rich Repeat Ribosomal_S10 PF00338.22 CDJ86212.1 - 0.085 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e DUF3557 PF12078.8 CDJ86212.1 - 0.59 10.1 8.5 1.1 9.1 4.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3557) LRR_2 PF07723.13 CDJ86212.1 - 2.8 8.7 5.0 1.2e+02 3.5 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat CSTF_C PF14304.6 CDJ86212.1 - 7.8 6.2 8.5 31 4.3 0.1 3.7 4 0 0 4 4 4 0 Transcription termination and cleavage factor C-terminal Trypsin PF00089.26 CDJ86213.1 - 2.7e-58 197.4 0.1 3.2e-58 197.2 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CDJ86213.1 - 2.9e-05 25.0 0.0 5.4e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CDJ86213.1 - 5.3e-05 23.6 0.1 0.00011 22.5 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) HOOK PF05622.12 CDJ86214.1 - 7.1e-70 236.0 55.7 8.7e-70 235.7 55.7 1.0 1 0 0 1 1 1 1 HOOK protein NUDIX PF00293.28 CDJ86215.1 - 3.5e-16 59.5 0.0 4.6e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain zf-C2H2_4 PF13894.6 CDJ86216.1 - 0.011 16.5 0.9 0.011 16.5 0.9 4.6 3 2 2 5 5 5 0 C2H2-type zinc finger STb_secrete PF09075.10 CDJ86216.1 - 0.013 15.5 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Heat-stable enterotoxin B, secretory zinc-ribbons_6 PF07191.12 CDJ86216.1 - 4.8 7.2 14.4 2.4 8.2 0.5 3.3 3 0 0 3 3 3 0 zinc-ribbons Peptidase_M23 PF01551.22 CDJ86217.1 - 1.6e-13 50.7 0.0 3.6e-12 46.3 0.0 2.3 2 0 0 2 2 2 1 Peptidase family M23 DUF1690 PF07956.11 CDJ86218.1 - 0.00039 20.9 4.1 0.00055 20.4 4.1 1.4 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) NDUF_B7 PF05676.13 CDJ86218.1 - 0.0047 16.6 0.6 0.01 15.5 0.6 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.13 CDJ86218.1 - 0.0081 16.3 0.1 0.013 15.7 0.1 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 CDJ86218.1 - 0.015 15.3 0.5 7.3 6.7 0.0 2.6 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, AAA_assoc_C PF09821.9 CDJ86218.1 - 0.12 12.9 0.2 7.4 7.1 0.0 2.2 2 0 0 2 2 2 0 C-terminal AAA-associated domain UPF0242 PF06785.11 CDJ86218.1 - 0.14 12.3 1.2 0.16 12.1 1.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YhhN PF07947.14 CDJ86219.1 - 6.9e-27 94.2 8.4 1.5e-26 93.2 8.4 1.6 1 0 0 1 1 1 1 YhhN family Exostosin PF03016.15 CDJ86219.1 - 1.3e-10 41.0 0.1 1e-09 38.0 0.0 2.3 2 1 1 3 3 3 1 Exostosin family Glyco_transf_64 PF09258.10 CDJ86219.1 - 0.00043 19.6 0.1 0.00076 18.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain DPM3 PF08285.11 CDJ86220.1 - 0.033 14.4 3.6 1.8 8.8 0.2 2.4 2 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Ribosomal_L35Ae PF01247.18 CDJ86221.1 - 4e-42 142.3 0.4 4.6e-42 142.1 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 CDJ86221.1 - 0.008 16.4 0.0 0.71 10.1 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain AA_permease PF00324.21 CDJ86222.1 - 1.7e-35 122.5 35.0 1.7e-35 122.5 35.0 2.0 2 0 0 2 2 2 1 Amino acid permease AA_permease_2 PF13520.6 CDJ86222.1 - 4.5e-13 48.8 35.0 4.5e-13 48.8 35.0 2.0 2 0 0 2 2 2 1 Amino acid permease Ion_trans_2 PF07885.16 CDJ86223.1 - 7.1e-35 118.8 19.9 8.1e-18 64.2 1.9 2.7 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CDJ86223.1 - 3.6e-08 32.9 3.8 0.0047 16.2 2.8 2.2 1 1 0 2 2 2 2 Ion transport protein DUF2178 PF09946.9 CDJ86223.1 - 0.003 17.7 1.0 0.08 13.1 0.0 2.5 2 1 1 3 3 3 1 Predicted membrane protein (DUF2178) Y_phosphatase PF00102.27 CDJ86225.1 - 1.3e-67 227.8 0.0 2.1e-67 227.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PDZ PF00595.24 CDJ86225.1 - 1.5e-19 70.1 0.0 2.6e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDJ86225.1 - 3.8e-06 26.7 0.0 7.4e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Y_phosphatase3 PF13350.6 CDJ86225.1 - 0.0001 22.4 0.0 0.00017 21.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CDJ86225.1 - 0.0028 17.5 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PAP1 PF08601.10 CDJ86225.1 - 0.011 15.5 9.3 0.016 15.0 9.3 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 PDZ_2 PF13180.6 CDJ86225.1 - 0.02 15.2 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 PDZ domain DUF2362 PF10154.9 CDJ86226.1 - 2.2e-48 165.5 0.8 3.2e-48 164.9 0.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) Filament PF00038.21 CDJ86226.1 - 0.0015 18.2 0.5 0.0027 17.3 0.5 1.3 1 0 0 1 1 1 1 Intermediate filament protein UPF0242 PF06785.11 CDJ86226.1 - 0.14 12.3 1.2 0.2 11.7 0.7 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMF_TATA_bd PF12325.8 CDJ86226.1 - 2.4 8.4 5.7 0.34 11.2 1.2 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TTL PF03133.15 CDJ86227.1 - 7.2e-84 281.4 0.0 2.5e-83 279.6 0.0 1.7 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family DUF2362 PF10154.9 CDJ86227.1 - 4.1e-51 174.5 0.2 8.5e-51 173.4 0.2 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) ATPgrasp_YheCD PF14398.6 CDJ86227.1 - 2.4e-06 27.0 0.0 0.0008 18.7 0.0 2.4 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CDJ86227.1 - 6.7e-05 22.3 0.0 0.1 11.8 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp DUF5553 PF17707.1 CDJ86227.1 - 0.28 10.6 1.8 0.55 9.6 1.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5553) GrlR PF16518.5 CDJ86228.1 - 0.028 14.4 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 T3SS negative regulator,GrlR Fusion_F0 PF13044.6 CDJ86228.1 - 0.033 12.9 0.1 0.039 12.6 0.1 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0, Isavirus rve PF00665.26 CDJ86229.1 - 2.6e-48 163.1 0.2 4.6e-25 88.1 0.0 3.8 4 0 0 4 4 4 2 Integrase core domain RT_RNaseH_2 PF17919.1 CDJ86229.1 - 4.4e-34 116.5 0.0 2.3e-33 114.2 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ86229.1 - 5.9e-30 103.7 0.0 2.7e-29 101.6 0.0 2.2 3 0 0 3 3 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ86229.1 - 4.1e-22 78.8 0.0 7.7e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ86229.1 - 9.1e-17 60.9 0.0 2.1e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CDJ86229.1 - 3.9e-12 45.8 0.1 0.00015 21.5 0.0 2.7 2 0 0 2 2 2 2 Integrase core domain zf-H2C2 PF09337.10 CDJ86229.1 - 0.0023 18.1 0.0 0.0073 16.5 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger HisKA PF00512.25 CDJ86229.1 - 0.0029 17.6 2.4 0.97 9.5 0.2 3.1 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain RTBV_P12 PF06361.11 CDJ86229.1 - 0.0029 18.0 0.4 4.3 7.8 0.0 2.5 2 0 0 2 2 2 2 Rice tungro bacilliform virus P12 protein DUF4326 PF14216.6 CDJ86229.1 - 0.015 16.0 0.0 3 8.6 0.0 3.1 3 0 0 3 3 2 0 Domain of unknown function (DUF4326) DUF3567 PF12091.8 CDJ86229.1 - 0.018 15.1 0.0 12 6.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3567) Peptidase_M50 PF02163.22 CDJ86229.1 - 0.056 12.7 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M50 Phenol_hyd_sub PF06099.11 CDJ86229.1 - 0.074 13.1 0.7 17 5.5 0.1 2.4 2 0 0 2 2 2 0 Phenol hydroxylase subunit Pex19 PF04614.12 CDJ86229.1 - 0.14 12.0 0.4 17 5.1 0.1 2.3 2 0 0 2 2 2 0 Pex19 protein family gag-asp_proteas PF13975.6 CDJ86230.1 - 3.6e-05 24.2 0.2 0.00012 22.5 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ86230.1 - 8.9e-05 23.1 0.0 0.00033 21.2 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ86230.1 - 0.0011 19.3 0.3 0.0048 17.2 0.0 2.1 2 0 0 2 2 2 1 Retroviral aspartyl protease Allexi_40kDa PF05549.11 CDJ86230.1 - 0.014 14.9 3.5 2.2 7.8 0.8 2.3 2 0 0 2 2 2 0 Allexivirus 40kDa protein Chibby PF14645.6 CDJ86230.1 - 0.13 12.7 0.3 0.13 12.7 0.3 2.5 3 0 0 3 3 3 0 Chibby family MctB PF11382.8 CDJ86230.1 - 0.93 9.1 4.4 1.7 8.3 4.4 1.3 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB ZapB PF06005.12 CDJ86230.1 - 2.6 8.6 13.9 0.39 11.2 9.4 1.9 2 0 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 CDJ86230.1 - 4.2 7.2 10.5 12 5.7 10.5 1.7 1 0 0 1 1 1 0 Septum formation initiator Tex_N PF09371.10 CDJ86231.1 - 2.5e-05 24.0 1.3 3e-05 23.8 1.3 1.0 1 0 0 1 1 1 1 Tex-like protein N-terminal domain Hrs_helical PF12210.8 CDJ86231.1 - 0.0079 16.7 0.1 0.0088 16.6 0.1 1.1 1 0 0 1 1 1 1 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF3487 PF11990.8 CDJ86232.1 - 3 7.8 8.5 3.8 7.4 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) Casein_kappa PF00997.18 CDJ86235.1 - 9.8 6.2 6.3 13 5.8 6.3 1.1 1 0 0 1 1 1 0 Kappa casein SpoIIIAH PF12685.7 CDJ86237.1 - 0.041 13.7 2.8 0.051 13.4 2.8 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein ArfGap PF01412.18 CDJ86240.1 - 9.6e-40 135.3 0.0 2.5e-39 134.0 0.0 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ras PF00071.22 CDJ86240.1 - 1.6e-21 76.6 0.0 2.9e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Ras family Ank_2 PF12796.7 CDJ86240.1 - 2.9e-06 27.8 0.0 5.5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) PH PF00169.29 CDJ86240.1 - 4.4e-06 27.2 0.1 0.061 13.8 0.0 2.5 2 0 0 2 2 2 2 PH domain Roc PF08477.13 CDJ86240.1 - 8.2e-06 26.0 0.2 0.00027 21.2 0.2 2.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ank PF00023.30 CDJ86240.1 - 2.9e-05 24.3 0.1 0.00013 22.3 0.1 2.2 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 CDJ86240.1 - 5.3e-05 23.7 0.9 0.0082 16.7 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ86240.1 - 0.0008 19.7 0.0 0.0022 18.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ86240.1 - 0.00093 19.5 0.1 0.0074 16.7 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeat PH_11 PF15413.6 CDJ86240.1 - 0.0043 17.4 0.2 0.29 11.6 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain YidD PF01809.18 CDJ86240.1 - 0.039 13.8 0.2 0.55 10.1 0.0 2.2 2 0 0 2 2 2 0 Putative membrane protein insertion efficiency factor F-box_4 PF15966.5 CDJ86240.1 - 0.12 12.3 1.3 0.45 10.4 0.0 2.6 3 0 0 3 3 3 0 F-box RRM_1 PF00076.22 CDJ86241.1 - 1.5e-15 56.7 0.0 3.1e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hemerythrin PF01814.23 CDJ86242.1 - 0.053 14.1 2.9 0.096 13.3 2.9 1.4 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain DUF4509 PF14970.6 CDJ86243.1 - 0.014 15.4 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) ING PF12998.7 CDJ86244.1 - 6.5e-10 39.5 1.6 6.5e-10 39.5 1.6 2.0 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CDJ86244.1 - 1.3e-05 25.0 12.5 2.8e-05 23.9 12.5 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CDJ86244.1 - 0.1 12.8 3.4 0.39 11.0 3.4 2.0 1 0 0 1 1 1 0 PHD-like zinc-binding domain YafO_toxin PF13957.6 CDJ86244.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Toxin YafO, type II toxin-antitoxin system PDZ PF00595.24 CDJ86245.1 - 1.5e-36 124.6 3.9 5.2e-12 45.9 0.1 3.6 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 CDJ86245.1 - 5.3e-23 80.6 2.5 2.9e-09 36.6 0.2 3.6 3 0 0 3 3 3 3 PDZ domain FERM_M PF00373.18 CDJ86245.1 - 4.6e-21 75.4 0.0 1.3e-20 74.0 0.0 1.7 1 0 0 1 1 1 1 FERM central domain PDZ_2 PF13180.6 CDJ86245.1 - 8.7e-16 58.0 3.0 0.00022 21.5 0.1 3.7 3 0 0 3 3 3 3 PDZ domain FERM_N PF09379.10 CDJ86245.1 - 4.5e-15 55.3 0.1 1.8e-14 53.4 0.1 2.1 2 0 0 2 2 2 1 FERM N-terminal domain FERM_C PF09380.10 CDJ86245.1 - 1.1e-12 48.2 1.3 1.6e-12 47.6 0.3 1.8 2 0 0 2 2 2 1 FERM C-terminal PH-like domain Tricorn_PDZ PF14685.6 CDJ86245.1 - 0.0033 17.3 2.9 1.1 9.2 0.1 3.9 4 0 0 4 4 4 1 Tricorn protease PDZ domain PDZ_4 PF17816.1 CDJ86245.1 - 0.0076 16.6 0.0 12 6.3 0.0 3.6 3 1 1 4 4 4 2 PDZ domain CTD PF12815.7 CDJ86246.1 - 1.4e-09 38.4 32.6 2.2e-06 28.1 9.4 8.3 3 2 3 6 6 6 3 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF836 PF05768.14 CDJ86246.1 - 0.042 14.3 0.1 0.082 13.3 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) SNF PF00209.18 CDJ86247.1 - 3.1e-13 49.3 2.1 4e-13 48.9 2.1 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family GEMIN8 PF15348.6 CDJ86247.1 - 0.036 14.4 0.5 0.051 13.9 0.5 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 RecO_C PF02565.15 CDJ86247.1 - 0.18 11.6 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Recombination protein O C terminal MPC PF03650.13 CDJ86250.1 - 1e-34 119.0 0.2 1.7e-34 118.2 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers HEAT PF02985.22 CDJ86251.1 - 0.00073 19.6 0.8 7 7.2 0.0 5.2 4 0 0 4 4 4 1 HEAT repeat DUF150_C PF17384.2 CDJ86251.1 - 0.032 14.4 0.1 0.087 13.0 0.1 1.7 1 0 0 1 1 1 0 RimP C-terminal SH3 domain Adaptin_N PF01602.20 CDJ86251.1 - 0.32 9.5 9.0 0.16 10.5 4.4 2.4 2 0 0 2 2 2 0 Adaptin N terminal region Cnd1 PF12717.7 CDJ86251.1 - 0.38 10.8 11.4 0.072 13.1 0.9 4.6 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 zf-C3Hc3H PF13891.6 CDJ86252.1 - 3.8e-06 27.2 3.6 9e-06 26.0 3.6 1.5 1 0 0 1 1 1 1 Potential DNA-binding domain PRAI PF00697.22 CDJ86252.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase FH2 PF02181.23 CDJ86253.1 - 5.8e-70 236.3 13.8 1.2e-69 235.3 13.8 1.5 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 CDJ86253.1 - 2e-34 119.0 0.1 1.1e-33 116.5 0.0 2.4 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 CDJ86253.1 - 6.1e-06 25.9 0.1 3.8e-05 23.3 0.1 2.4 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain DUF1844 PF08899.11 CDJ86253.1 - 2.7 8.3 7.9 0.25 11.6 0.6 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF1844) EGF_2 PF07974.13 CDJ86254.1 - 0.033 14.5 26.7 0.094 13.1 8.2 2.7 2 0 0 2 2 2 0 EGF-like domain HRM PF02793.22 CDJ86254.1 - 0.19 12.0 13.0 4.8 7.5 0.2 2.6 2 0 0 2 2 2 0 Hormone receptor domain Laminin_EGF PF00053.24 CDJ86254.1 - 0.25 11.5 23.9 6.9 6.9 11.7 3.1 1 1 1 2 2 2 0 Laminin EGF domain EGF PF00008.27 CDJ86254.1 - 1.1 9.6 16.2 3.8 7.9 4.7 2.5 2 0 0 2 2 2 0 EGF-like domain RT_RNaseH_2 PF17919.1 CDJ86255.1 - 7.8e-37 125.3 0.0 2.9e-36 123.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ86255.1 - 3.3e-33 114.1 0.0 1.5e-32 112.0 0.0 2.1 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ86255.1 - 5.7e-23 81.4 0.0 1.8e-22 79.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CDJ86255.1 - 1e-21 77.5 0.0 1.9e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ86255.1 - 1.4e-17 63.5 0.1 3.6e-17 62.2 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CDJ86255.1 - 2.9e-05 23.8 0.1 0.00011 21.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 CDJ86255.1 - 0.043 14.0 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCHC PF00098.23 CDJ86256.1 - 0.66 10.2 15.4 1.5 9.0 2.9 3.0 2 1 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ86256.1 - 8 6.3 10.4 0.81 9.5 3.3 2.5 1 1 1 2 2 2 0 Zinc knuckle DUF334 PF03904.13 CDJ86258.1 - 0.082 12.4 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF334) WD40 PF00400.32 CDJ86259.1 - 3.5e-19 68.8 0.3 0.00014 22.5 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Acyltransferase PF01553.21 CDJ86260.1 - 3.6e-15 55.8 0.0 5.9e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase zf-CCHC_4 PF14392.6 CDJ86263.1 - 0.16 11.8 1.3 0.42 10.4 1.3 1.8 1 0 0 1 1 1 0 Zinc knuckle F-box-like PF12937.7 CDJ86265.1 - 2e-07 30.8 0.1 8.7e-07 28.7 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CDJ86265.1 - 6.8e-07 29.0 0.5 6.8e-07 29.0 0.5 2.8 3 0 0 3 3 3 1 F-box domain Motile_Sperm PF00635.26 CDJ86267.1 - 0.00018 21.3 0.0 0.00023 21.0 0.0 1.1 1 0 0 1 1 1 1 MSP (Major sperm protein) domain RCR PF12273.8 CDJ86268.1 - 0.003 18.2 0.2 0.0045 17.6 0.2 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Adeno_E3_CR2 PF02439.15 CDJ86268.1 - 0.033 13.9 0.7 0.048 13.4 0.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 CDJ86268.1 - 0.041 14.8 0.0 0.06 14.2 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.11 CDJ86268.1 - 0.042 13.4 0.5 0.066 12.8 0.5 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF948 PF06103.11 CDJ86268.1 - 0.082 13.2 0.1 0.12 12.7 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF4446 PF14584.6 CDJ86268.1 - 0.11 12.5 0.2 0.14 12.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) WBP-1 PF11669.8 CDJ86268.1 - 0.31 11.7 1.0 1.2 9.8 1.0 1.9 1 1 0 1 1 1 0 WW domain-binding protein 1 adh_short PF00106.25 CDJ86269.1 - 3.4e-27 95.2 0.0 5.2e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ86269.1 - 4.7e-20 72.2 0.0 7.4e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Exo_endo_phos_2 PF14529.6 CDJ86269.1 - 1.9e-10 40.7 0.1 3.7e-10 39.7 0.1 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase KR PF08659.10 CDJ86269.1 - 1.2e-06 28.6 0.1 1.8e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 KR domain RVT_1 PF00078.27 CDJ86269.1 - 0.015 14.9 0.0 0.039 13.5 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) C1_1 PF00130.22 CDJ86270.1 - 1.8e-30 104.6 20.0 3.6e-15 55.6 9.2 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 CDJ86270.1 - 1.5e-06 28.4 18.7 2.3e-05 24.6 3.5 2.6 2 0 0 2 2 2 2 C1 domain PH PF00169.29 CDJ86270.1 - 3.6e-06 27.4 2.3 4.7e-06 27.1 0.6 2.1 2 0 0 2 2 2 1 PH domain PHD PF00628.29 CDJ86270.1 - 0.011 15.6 18.7 0.37 10.7 3.1 2.5 2 0 0 2 2 2 0 PHD-finger zf-RING_9 PF13901.6 CDJ86270.1 - 0.031 14.3 20.8 0.06 13.3 3.7 2.8 3 1 0 3 3 3 0 Putative zinc-RING and/or ribbon CaMBD PF02888.16 CDJ86270.1 - 0.073 13.3 1.2 0.53 10.5 1.2 2.3 2 0 0 2 2 2 0 Calmodulin binding domain FYVE_2 PF02318.16 CDJ86270.1 - 0.59 10.4 13.1 0.15 12.2 3.7 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger Zf_RING PF16744.5 CDJ86270.1 - 0.88 9.7 12.9 6.2 7.0 4.4 2.8 3 0 0 3 3 3 0 KIAA1045 RING finger PHD_2 PF13831.6 CDJ86270.1 - 2.4 7.8 10.1 1.5 8.4 0.2 2.8 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.6 CDJ86270.1 - 3.1 7.8 16.5 0.33 10.9 1.6 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 UPF0542 PF15086.6 CDJ86271.1 - 9.3e-09 35.1 1.8 1.1e-08 34.8 1.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0542 MSC PF09402.10 CDJ86271.1 - 0.017 14.6 0.9 0.018 14.5 0.9 1.0 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain SDH_sah PF01972.16 CDJ86271.1 - 0.029 13.4 0.4 0.037 13.0 0.4 1.1 1 0 0 1 1 1 0 Serine dehydrogenase proteinase NicO PF03824.16 CDJ86271.1 - 0.039 13.3 0.4 0.036 13.4 0.4 1.0 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF148 PF02520.17 CDJ86272.1 - 0.00014 21.9 2.2 0.00014 21.9 2.2 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF148 EcKinase PF02958.20 CDJ86272.1 - 0.021 14.1 2.5 0.034 13.5 2.5 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase ZapB PF06005.12 CDJ86272.1 - 0.031 14.7 2.7 0.031 14.7 2.7 2.3 1 1 1 2 2 2 0 Cell division protein ZapB DUF3450 PF11932.8 CDJ86272.1 - 0.032 13.5 1.1 0.49 9.7 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Metal_resist PF13801.6 CDJ86272.1 - 0.043 14.0 2.1 32 4.7 3.2 3.0 2 1 1 3 3 3 0 Heavy-metal resistance ATP-synt_D PF01813.17 CDJ86272.1 - 0.045 13.6 4.6 0.087 12.7 4.6 1.5 1 0 0 1 1 1 0 ATP synthase subunit D DUF3268 PF11672.8 CDJ86272.1 - 0.059 13.7 0.7 1.3 9.3 0.0 2.3 1 1 1 2 2 2 0 zinc-finger-containing domain FAD-SLDH PF12318.8 CDJ86272.1 - 0.068 13.2 0.4 0.1 12.7 0.4 1.3 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase Rtt106_N PF18215.1 CDJ86272.1 - 0.1 12.4 0.0 4.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Histone chaperone Rtt106 N-terminal domain JIP_LZII PF16471.5 CDJ86272.1 - 0.11 12.7 2.6 0.39 10.9 1.8 2.3 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II KfrA_N PF11740.8 CDJ86272.1 - 0.14 12.9 4.0 8 7.2 4.6 2.6 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Mit_ribos_Mrp51 PF11709.8 CDJ86272.1 - 0.16 11.6 3.8 0.21 11.1 3.8 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit THDPS_N_2 PF14805.6 CDJ86272.1 - 0.16 12.2 1.2 0.4 10.9 0.1 2.2 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Uteroglobin PF01099.17 CDJ86272.1 - 0.16 12.3 1.6 4 7.8 0.9 2.5 2 1 0 2 2 2 0 Uteroglobin family OmpH PF03938.14 CDJ86272.1 - 0.88 9.9 9.2 0.27 11.6 6.3 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) EF-G-binding_N PF07299.11 CDJ86273.1 - 0.15 12.6 0.9 0.23 12.0 0.9 1.4 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal VSG_B PF13206.6 CDJ86273.1 - 1.8 7.7 7.8 2.3 7.4 7.8 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain CDC45 PF02724.14 CDJ86273.1 - 7.5 4.7 10.5 8.5 4.5 10.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3854 PF12965.7 CDJ86274.1 - 0.028 14.4 0.2 0.052 13.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) DUF2207 PF09972.9 CDJ86274.1 - 0.59 8.8 6.4 0.97 8.1 6.0 1.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Rrn6 PF10214.9 CDJ86274.1 - 2.2 6.7 7.7 2.4 6.5 7.7 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CDC45 PF02724.14 CDJ86274.1 - 3.2 5.9 15.1 3.6 5.8 15.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 CDJ86274.1 - 5.1 6.4 24.8 7.4 5.9 24.8 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Acyl-CoA_dh_1 PF00441.24 CDJ86275.1 - 6.4e-39 133.6 1.0 3.4e-37 128.0 0.4 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CDJ86275.1 - 6.4e-26 90.4 0.0 1.3e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CDJ86275.1 - 2.4e-24 86.2 0.0 5.1e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CDJ86275.1 - 1.1e-14 54.8 0.0 4.3e-13 49.7 0.0 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 CDJ86276.1 - 1.4e-38 132.4 1.4 9e-38 129.8 0.3 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CDJ86276.1 - 2.6e-25 88.5 0.0 5.7e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CDJ86276.1 - 1.3e-22 80.6 0.0 2.9e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CDJ86276.1 - 1e-14 54.9 0.0 7.3e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain BTB PF00651.31 CDJ86277.1 - 2.2e-26 92.3 0.1 1e-25 90.1 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 CDJ86277.1 - 0.00011 22.2 0.1 0.00064 19.8 0.1 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Amidase PF01425.21 CDJ86278.1 - 2.2e-58 198.3 0.0 2.6e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Amidase zf-C2H2 PF00096.26 CDJ86279.1 - 5e-17 61.3 26.2 8.7e-06 25.9 1.4 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ86279.1 - 6.4e-14 51.6 22.0 2.6e-05 24.4 0.0 6.2 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDJ86279.1 - 9.7e-13 47.8 28.8 0.0062 17.3 3.9 5.0 5 0 0 5 5 4 4 C2H2-type zinc finger zf-met PF12874.7 CDJ86279.1 - 1.4e-06 28.5 19.2 0.0019 18.5 0.1 4.6 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CDJ86279.1 - 6.3e-06 26.1 27.2 0.0093 16.0 0.4 5.0 4 1 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ86279.1 - 0.00031 20.9 17.6 0.06 13.7 0.1 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-MYND PF01753.18 CDJ86279.1 - 0.012 15.6 0.2 0.13 12.4 0.0 2.6 2 2 0 2 2 2 0 MYND finger Sina PF03145.16 CDJ86279.1 - 0.013 15.5 0.5 0.013 15.5 0.5 2.1 2 1 0 2 2 2 0 Seven in absentia protein family zf-Di19 PF05605.12 CDJ86279.1 - 0.018 15.3 16.8 0.72 10.2 1.1 3.4 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 CDJ86279.1 - 0.033 14.0 3.7 0.93 9.3 0.0 3.5 2 1 2 4 4 4 0 GAGA factor zf-MYST PF17772.1 CDJ86279.1 - 0.063 12.9 0.1 0.063 12.9 0.1 3.4 3 1 1 4 4 4 0 MYST family zinc finger domain zf-C2H2_2 PF12756.7 CDJ86279.1 - 0.29 11.5 17.2 5.3 7.4 1.3 4.2 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_8 PF15909.5 CDJ86279.1 - 0.37 11.1 9.7 0.13 12.6 1.3 3.0 2 2 1 3 3 3 0 C2H2-type zinc ribbon CpXC PF14353.6 CDJ86279.1 - 0.52 10.4 5.7 8.2 6.5 0.3 2.6 1 1 1 2 2 2 0 CpXC protein DZR PF12773.7 CDJ86279.1 - 0.68 10.0 7.9 0.45 10.6 4.3 2.5 2 1 0 2 2 2 0 Double zinc ribbon zf-C2HE PF16278.5 CDJ86279.1 - 2.5 8.6 15.4 0.23 11.9 1.4 3.7 3 1 1 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 CDJ86279.1 - 2.6 8.2 11.2 0.42 10.8 3.2 3.2 3 0 0 3 3 3 0 Zinc ribbon domain FYVE PF01363.21 CDJ86279.1 - 2.8 8.1 14.8 2.3e+02 2.0 0.1 3.3 2 1 0 2 2 2 0 FYVE zinc finger zf-C2HC_2 PF13913.6 CDJ86279.1 - 3.3 7.7 16.0 2.7 8.0 0.8 4.5 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-BED PF02892.15 CDJ86279.1 - 5.1 7.2 18.6 10 6.3 2.2 4.3 3 1 1 4 4 4 0 BED zinc finger zf-AN1 PF01428.16 CDJ86279.1 - 5.5 7.2 11.3 11 6.2 0.2 4.1 4 0 0 4 4 4 0 AN1-like Zinc finger DUF2256 PF10013.9 CDJ86279.1 - 9.6 6.4 10.8 11 6.2 0.1 4.0 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) BTB PF00651.31 CDJ86280.1 - 1.4e-21 76.8 0.3 2.8e-21 75.8 0.1 1.6 2 0 0 2 2 2 1 BTB/POZ domain MATH PF00917.26 CDJ86280.1 - 7.6e-18 64.7 0.1 1.3e-17 64.0 0.1 1.3 1 0 0 1 1 1 1 MATH domain OAD_gamma PF04277.13 CDJ86281.1 - 0.00049 20.6 0.1 0.00097 19.7 0.1 1.4 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain DUF3810 PF12725.7 CDJ86281.1 - 0.0035 16.8 0.1 0.0058 16.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3810) Ac76 PF05814.11 CDJ86281.1 - 0.0079 16.2 1.1 0.015 15.3 1.1 1.4 1 0 0 1 1 1 1 Orf76 (Ac76) DUF4064 PF13273.6 CDJ86281.1 - 0.01 16.1 0.0 0.015 15.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) SpoIIIAH PF12685.7 CDJ86281.1 - 0.041 13.7 0.2 0.067 13.0 0.2 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Gly-zipper_YMGG PF13441.6 CDJ86281.1 - 0.049 13.4 21.1 0.1 12.4 21.1 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF4834 PF16118.5 CDJ86281.1 - 0.16 13.0 0.1 0.69 10.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) EphA2_TM PF14575.6 CDJ86281.1 - 0.17 12.8 0.0 0.17 12.8 0.0 2.3 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain FAM199X PF15814.5 CDJ86281.1 - 5.4 6.0 7.3 8.5 5.3 7.3 1.2 1 0 0 1 1 1 0 Protein family FAM199X SIT PF15330.6 CDJ86281.1 - 5.6 7.5 5.8 19 5.7 0.0 2.5 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Chibby PF14645.6 CDJ86282.1 - 0.0025 18.2 0.8 4.4 7.7 0.0 3.0 2 1 0 2 2 2 1 Chibby family FPP PF05911.11 CDJ86282.1 - 0.033 12.4 20.2 0.078 11.2 10.2 2.1 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil ADIP PF11559.8 CDJ86282.1 - 0.57 10.3 22.6 1.9 8.6 6.6 3.3 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF1515 PF07439.11 CDJ86282.1 - 1.6 8.8 8.8 6.2 6.9 2.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) bZIP_1 PF00170.21 CDJ86282.1 - 2.7 8.1 23.7 0.48 10.6 3.2 3.8 2 1 0 3 3 3 0 bZIP transcription factor DUF4686 PF15742.5 CDJ86282.1 - 3.4 6.7 28.6 0.05 12.7 9.9 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4686) Spc7 PF08317.11 CDJ86282.1 - 5.9 5.7 27.8 1.8 7.3 2.0 2.7 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.6 CDJ86282.1 - 6 6.1 11.5 72 2.6 11.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 CDJ86282.1 - 8.8 6.3 31.5 2.1e+02 1.9 21.6 3.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FapA PF03961.13 CDJ86282.1 - 9.2 4.7 16.8 3.6 6.1 3.1 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A zf-UBP PF02148.19 CDJ86284.1 - 9.3e-18 64.3 10.9 1.2e-17 63.9 10.9 1.2 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Hist_deacetyl PF00850.19 CDJ86285.1 - 2.3e-23 83.1 0.0 2.8e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain TRAM_LAG1_CLN8 PF03798.16 CDJ86286.1 - 2.8e-16 59.9 18.3 2.8e-16 59.9 18.3 1.9 1 1 1 2 2 2 1 TLC domain Hist_deacetyl PF00850.19 CDJ86287.1 - 6.5e-88 295.2 0.9 4e-78 263.0 0.1 2.1 2 0 0 2 2 2 2 Histone deacetylase domain DuoxA PF10204.9 CDJ86288.1 - 1.2e-71 241.0 5.5 1.4e-71 240.7 5.5 1.0 1 0 0 1 1 1 1 Dual oxidase maturation factor Doppel PF11466.8 CDJ86288.1 - 0.076 12.7 2.1 0.19 11.4 2.1 1.6 1 0 0 1 1 1 0 Prion-like protein Doppel NHL PF01436.21 CDJ86289.1 - 6.3e-44 145.9 20.3 1.7e-09 37.2 0.1 6.5 6 0 0 6 6 6 6 NHL repeat DUF5128 PF17170.4 CDJ86289.1 - 6.6e-21 74.8 5.7 5.1e-08 32.4 0.1 4.2 2 1 2 4 4 4 4 6-bladed beta-propeller SGL PF08450.12 CDJ86289.1 - 2.6e-10 40.3 0.1 1.5e-05 24.7 0.0 3.0 3 0 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region zf-C3HC4 PF00097.25 CDJ86289.1 - 1.2e-09 37.9 14.0 1.2e-09 37.9 14.0 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ86289.1 - 9.5e-09 35.2 13.4 9.5e-09 35.2 13.4 2.3 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDJ86289.1 - 2.4e-07 30.5 11.5 2.4e-07 30.5 11.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ86289.1 - 1.7e-06 27.8 15.0 1.7e-06 27.8 15.0 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ86289.1 - 1e-05 25.6 14.9 1e-05 25.6 14.9 2.5 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CDJ86289.1 - 5.6e-05 23.0 12.0 5.6e-05 23.0 12.0 2.6 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CDJ86289.1 - 5.6e-05 23.4 13.5 5.6e-05 23.4 13.5 2.8 2 0 0 2 2 2 1 Ring finger domain Phytase-like PF13449.6 CDJ86289.1 - 0.00016 21.7 0.0 17 5.2 0.0 4.9 4 1 1 5 5 5 0 Esterase-like activity of phytase DUF4934 PF16288.5 CDJ86289.1 - 0.00065 19.6 5.1 0.11 12.4 0.1 3.5 1 1 4 5 5 5 3 Domain of unknown function (DUF4934) SBBP PF06739.11 CDJ86289.1 - 0.0038 17.2 1.4 0.47 10.5 0.0 2.8 3 0 0 3 3 3 1 Beta-propeller repeat RIH_assoc PF08454.11 CDJ86289.1 - 0.014 15.2 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 RyR and IP3R Homology associated zf-RING_11 PF17123.5 CDJ86289.1 - 0.025 14.3 3.5 0.072 12.9 3.5 1.9 1 0 0 1 1 1 0 RING-like zinc finger Lactonase PF10282.9 CDJ86289.1 - 0.026 13.8 0.3 0.71 9.1 0.1 2.4 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller HCNGP PF07818.13 CDJ86292.1 - 6.3e-15 55.6 0.0 1.2e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 HCNGP-like protein Chorion_S16 PF05836.12 CDJ86293.1 - 0.055 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Chorion protein S16 Caenor_Her-1 PF09232.10 CDJ86294.1 - 3.6e-27 95.1 16.6 4.2e-27 94.9 16.6 1.1 1 0 0 1 1 1 1 Caenorhabditis elegans Her-1 AAA PF00004.29 CDJ86294.1 - 0.0079 16.6 0.0 0.012 16.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rota_NSP4 PF01452.16 CDJ86294.1 - 0.05 13.3 0.3 0.078 12.6 0.2 1.3 1 1 0 1 1 1 0 Rotavirus non structural protein Bax1-I PF01027.20 CDJ86295.1 - 0.04 13.7 7.6 0.048 13.5 7.6 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 SHR3_chaperone PF08229.11 CDJ86295.1 - 0.097 11.6 0.5 0.14 11.2 0.5 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 Pex14_N PF04695.13 CDJ86295.1 - 0.49 11.0 3.0 0.74 10.5 3.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Phage_holin_3_6 PF07332.11 CDJ86295.1 - 0.94 9.5 4.0 1.4 9.0 4.0 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF805 PF05656.14 CDJ86295.1 - 0.95 9.9 4.8 1.6 9.1 4.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF805) CAP PF00188.26 CDJ86296.1 - 1.9e-34 119.2 12.2 7.5e-17 62.3 0.8 2.2 2 0 0 2 2 2 2 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ86296.1 - 1.2e-05 25.6 0.7 0.21 11.9 0.1 2.7 2 0 0 2 2 2 2 Ancylostoma-associated secreted protein related RPN5_C PF18098.1 CDJ86296.1 - 0.017 15.2 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN5 C-terminal domain ATP-synt_F6 PF05511.11 CDJ86296.1 - 0.097 13.1 0.0 9.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 Metallothio_Euk PF12749.7 CDJ86296.1 - 0.29 11.3 20.0 1.1 9.4 5.6 2.9 2 0 0 2 2 2 0 Eukaryotic metallothionein Metallothio_PEC PF02068.16 CDJ86296.1 - 0.49 10.8 26.8 1.1 9.7 9.7 2.7 2 0 0 2 2 2 0 Plant PEC family metallothionein Pilin_PilA PF14245.6 CDJ86296.1 - 2 8.4 4.7 1 9.4 0.5 2.5 2 1 0 2 2 2 0 Type IV pilin PilA Toxin_12 PF07740.12 CDJ86296.1 - 4.6 8.0 20.3 2.6 8.8 5.9 2.7 2 0 0 2 2 2 0 Ion channel inhibitory toxin Peptidase_M17 PF00883.21 CDJ86297.1 - 1.5e-16 60.6 0.0 2.1e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17 PF00883.21 CDJ86298.1 - 8.8e-34 117.2 0.0 1.1e-33 116.9 0.0 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain S-l_SbsC_C PF18316.1 CDJ86298.1 - 0.051 14.1 0.0 0.089 13.3 0.0 1.3 1 0 0 1 1 1 0 S-layer protein SbsC C-terminal domain Spc7 PF08317.11 CDJ86299.1 - 0.69 8.7 7.4 0.39 9.5 4.9 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein ARA70 PF12489.8 CDJ86299.1 - 1.3 9.2 11.3 0.13 12.4 2.0 3.0 3 1 0 3 3 3 0 Nuclear coactivator CAP PF00188.26 CDJ86300.1 - 1e-24 87.7 3.0 6e-17 62.7 0.8 2.3 2 0 0 2 2 2 2 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ86300.1 - 0.00089 19.5 0.3 0.11 12.8 0.1 2.6 2 0 0 2 2 2 2 Ancylostoma-associated secreted protein related ATP-synt_F6 PF05511.11 CDJ86300.1 - 0.058 13.8 0.0 6.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 Metallothio_PEC PF02068.16 CDJ86300.1 - 0.26 11.7 9.7 0.73 10.2 9.7 1.8 1 0 0 1 1 1 0 Plant PEC family metallothionein Pkinase PF00069.25 CDJ86302.1 - 3.9e-51 173.9 0.0 1.9e-50 171.7 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain CNH PF00780.22 CDJ86302.1 - 7.2e-38 130.8 0.0 1.3e-37 130.0 0.0 1.4 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.17 CDJ86302.1 - 1.2e-23 83.7 0.0 2.4e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 CDJ86302.1 - 4e-11 42.6 11.8 9.3e-11 41.5 11.8 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) KELK PF15796.5 CDJ86302.1 - 2.3e-08 34.4 15.3 2.3e-08 34.4 15.3 6.6 4 2 2 6 6 5 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase Kinase-like PF14531.6 CDJ86302.1 - 2.5e-06 27.1 0.0 7e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 CDJ86302.1 - 5e-05 23.9 0.8 0.00019 22.1 0.8 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain DMPK_coil PF08826.10 CDJ86302.1 - 0.00027 21.0 7.2 0.00027 21.0 7.2 7.3 6 3 3 9 9 9 1 DMPK coiled coil domain like PH PF00169.29 CDJ86302.1 - 0.00054 20.4 0.0 0.0023 18.4 0.0 2.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CDJ86302.1 - 0.018 15.5 0.5 0.072 13.5 0.0 2.4 2 0 0 2 2 1 0 Pleckstrin homology domain Haspin_kinase PF12330.8 CDJ86302.1 - 0.033 13.2 3.3 0.2 10.6 0.0 2.5 2 1 0 2 2 2 0 Haspin like kinase domain Filament PF00038.21 CDJ86302.1 - 0.26 10.8 71.8 0.094 12.3 45.8 3.6 2 1 1 3 3 3 0 Intermediate filament protein GIT_CC PF16559.5 CDJ86302.1 - 3 7.8 12.3 3.1 7.7 0.7 4.2 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor YozE_SAM_like PF06855.12 CDJ86303.1 - 0.17 12.1 0.1 0.71 10.1 0.0 1.9 2 0 0 2 2 2 0 YozE SAM-like fold Spore_GerAC PF05504.11 CDJ86304.1 - 0.054 13.7 0.2 0.094 12.9 0.2 1.5 1 1 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal RVT_1 PF00078.27 CDJ86305.1 - 9.3e-39 133.2 0.0 1.5e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Methyltr_RsmF_N PF17125.5 CDJ86305.1 - 0.19 12.2 0.0 0.91 10.1 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of 16S rRNA methyltransferase RsmF Actin_micro PF17003.5 CDJ86307.1 - 0.0035 16.6 3.6 0.082 12.1 0.0 3.4 2 1 1 3 3 3 2 Putative actin-like family GP67 PF17634.2 CDJ86308.1 - 0.24 11.8 8.6 0.74 10.3 1.6 2.3 2 0 0 2 2 2 0 Gene product 67 PPL5 PF18168.1 CDJ86308.1 - 1.4 8.1 8.4 0.15 11.4 0.8 2.4 2 0 0 2 2 2 0 Prim-pol family 5 RPA_interact_C PF14768.6 CDJ86309.1 - 7.1e-08 32.9 2.8 7.1e-08 32.9 2.8 1.6 2 0 0 2 2 2 1 Replication protein A interacting C-terminal RPA_interact_N PF14766.6 CDJ86309.1 - 4.1e-05 23.1 4.9 0.00019 21.0 5.5 1.8 2 0 0 2 2 2 1 Replication protein A interacting N-terminal Zn_Tnp_IS1595 PF12760.7 CDJ86309.1 - 0.0091 15.9 1.5 2.4 8.2 0.2 2.5 2 0 0 2 2 2 2 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.6 CDJ86309.1 - 0.036 14.0 3.6 6.8 6.7 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain IBR PF01485.21 CDJ86309.1 - 0.069 13.4 0.9 1.4 9.2 0.1 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain eIF-5_eIF-2B PF01873.17 CDJ86309.1 - 0.1 12.4 1.1 1 9.2 0.0 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 NleF_casp_inhib PF16809.5 CDJ86309.1 - 0.14 12.1 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 NleF caspase inhibitor Pkinase PF00069.25 CDJ86311.1 - 1.7e-57 194.8 0.0 1.9e-57 194.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ86311.1 - 2.1e-35 122.3 0.0 2.7e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ86311.1 - 0.00059 18.9 0.9 0.00083 18.4 0.9 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CDJ86311.1 - 0.0044 15.9 0.0 0.0084 14.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDJ86311.1 - 0.021 14.1 0.0 0.049 13.0 0.0 1.7 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 CDJ86311.1 - 0.054 13.4 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DSPc PF00782.20 CDJ86312.1 - 1.1e-32 112.6 0.0 5.2e-32 110.4 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDJ86312.1 - 9.5e-05 22.1 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CDJ86312.1 - 0.016 15.3 0.1 0.037 14.2 0.0 1.6 2 0 0 2 2 2 0 Inositol hexakisphosphate CDKN3 PF05706.12 CDJ86312.1 - 0.094 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Glyco_hydro_108 PF05838.12 CDJ86312.1 - 0.12 12.9 0.0 0.73 10.3 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase 108 DUF4453 PF14627.6 CDJ86312.1 - 0.15 12.1 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) PP2C PF00481.21 CDJ86313.1 - 4.2e-53 180.6 0.0 6.2e-53 180.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CDJ86313.1 - 0.0036 17.0 0.0 0.2 11.3 0.0 2.8 2 1 1 3 3 3 1 Protein phosphatase 2C BTB PF00651.31 CDJ86314.1 - 4.7e-17 62.2 0.4 9.2e-17 61.3 0.4 1.5 1 0 0 1 1 1 1 BTB/POZ domain PRIMA1 PF16101.5 CDJ86315.1 - 0.56 10.2 3.0 1.7 8.7 3.0 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Pheromone PF08015.11 CDJ86315.1 - 0.73 10.9 8.5 0.5 11.5 2.6 3.0 3 0 0 3 3 3 0 Fungal mating-type pheromone EF-hand_6 PF13405.6 CDJ86316.1 - 0.046 13.7 0.0 0.16 12.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain Phage_holin_3_6 PF07332.11 CDJ86318.1 - 0.98 9.5 22.8 1.2 9.2 22.8 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III LMF1 PF06762.14 CDJ86318.1 - 4.8 6.2 4.9 5 6.1 4.9 1.0 1 0 0 1 1 1 0 Lipase maturation factor DUF805 PF05656.14 CDJ86318.1 - 5.2 7.5 7.0 6.1 7.3 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF805) FA_desaturase PF00487.24 CDJ86318.1 - 8.3 6.2 6.5 8.1 6.2 6.5 1.1 1 0 0 1 1 1 0 Fatty acid desaturase Sugar_tr PF00083.24 CDJ86319.1 - 1.2e-23 83.7 23.4 1.6e-23 83.3 23.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ86319.1 - 8.9e-11 41.3 23.6 4.3e-09 35.8 14.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily COG7 PF10191.9 CDJ86320.1 - 4.4e-12 45.1 3.1 4.5e-07 28.5 0.0 2.7 2 1 0 2 2 2 2 Golgi complex component 7 (COG7) DUF1664 PF07889.12 CDJ86320.1 - 0.00046 20.2 5.9 0.0088 16.1 4.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1664) Snf7 PF03357.21 CDJ86320.1 - 0.023 14.3 1.1 0.023 14.3 1.1 2.4 2 0 0 2 2 2 0 Snf7 HsbA PF12296.8 CDJ86320.1 - 0.078 13.4 3.7 9 6.8 0.0 4.1 5 0 0 5 5 5 0 Hydrophobic surface binding protein A Laminin_II PF06009.12 CDJ86320.1 - 0.23 11.5 3.4 2.1 8.4 1.6 2.9 2 0 0 2 2 2 0 Laminin Domain II Sec20 PF03908.13 CDJ86320.1 - 0.53 10.2 3.9 3.3 7.7 1.8 3.0 1 1 1 2 2 2 0 Sec20 DUF2508 PF10704.9 CDJ86320.1 - 1.6 8.9 6.7 0.63 10.3 2.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2508) KxDL PF10241.9 CDJ86320.1 - 1.8 8.9 7.8 9 6.7 1.8 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein DUF4795 PF16043.5 CDJ86320.1 - 3.9 7.0 14.0 13 5.3 12.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) VWA PF00092.28 CDJ86322.1 - 5e-12 46.4 1.9 4.3e-11 43.4 0.2 2.4 3 0 0 3 3 3 1 von Willebrand factor type A domain EGF_2 PF07974.13 CDJ86322.1 - 0.00068 20.0 19.4 0.11 12.9 10.4 2.8 2 0 0 2 2 2 2 EGF-like domain DUF3467 PF11950.8 CDJ86322.1 - 0.0016 18.6 0.1 0.16 12.2 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3467) Laminin_EGF PF00053.24 CDJ86322.1 - 0.0025 17.9 13.9 0.02 15.0 4.7 2.7 1 1 1 2 2 2 2 Laminin EGF domain RVT_1 PF00078.27 CDJ86323.1 - 1.7e-09 37.6 0.0 2.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asn_synthase PF00733.21 CDJ86324.1 - 9.9e-48 163.6 1.0 1.3e-33 117.1 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase DUF244 PF03112.14 CDJ86324.1 - 0.023 14.6 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF GATase_7 PF13537.6 CDJ86325.1 - 2.8e-21 75.7 0.0 3.9e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CDJ86325.1 - 3.3e-20 72.6 0.0 4.9e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase domain CENP-T_C PF15511.6 CDJ86326.1 - 0.022 14.9 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Tis11B_N PF04553.12 CDJ86326.1 - 0.082 13.5 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Tis11B like protein, N terminus DUF2534 PF10749.9 CDJ86326.1 - 0.24 11.6 4.0 4.1 7.6 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2534) Col_cuticle_N PF01484.17 CDJ86326.1 - 1.1 9.3 5.3 1.2 9.3 0.0 3.1 2 1 1 3 3 3 0 Nematode cuticle collagen N-terminal domain Clathrin PF00637.20 CDJ86327.1 - 2.3e-10 40.5 31.6 0.0016 18.3 0.1 9.1 7 1 0 8 8 8 4 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 CDJ86327.1 - 5.6e-05 23.4 0.1 0.53 10.6 0.0 4.5 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_1 PF00515.28 CDJ86327.1 - 0.00069 19.3 30.3 0.036 13.9 0.1 10.6 10 1 1 11 11 11 2 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 CDJ86327.1 - 0.0013 17.8 0.1 0.0013 17.8 0.1 5.5 7 0 0 7 7 7 1 Coatomer WD associated region TPR_2 PF07719.17 CDJ86327.1 - 0.0044 17.0 42.7 0.55 10.5 0.1 13.0 13 2 2 15 15 15 2 Tetratricopeptide repeat DUF3592 PF12158.8 CDJ86327.1 - 0.032 14.3 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) TPR_8 PF13181.6 CDJ86327.1 - 0.099 12.9 24.5 0.72 10.2 0.1 7.8 7 0 0 7 7 7 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CDJ86327.1 - 0.47 10.5 14.3 2.2 8.2 0.4 5.9 6 1 0 6 6 6 0 Mad3/BUB1 homology region 1 WD40 PF00400.32 CDJ86327.1 - 1.4 9.9 4.9 7.9 7.5 0.0 4.1 5 0 0 5 5 5 0 WD domain, G-beta repeat TPR_11 PF13414.6 CDJ86327.1 - 6.9 6.4 9.1 26 4.6 0.3 5.8 7 0 0 7 7 7 0 TPR repeat FTHFS PF01268.19 CDJ86328.1 - 1.5e-196 653.9 0.4 1.7e-196 653.7 0.4 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase Pkinase PF00069.25 CDJ86329.1 - 1.7e-23 83.3 0.0 2.2e-23 83.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ86329.1 - 4.7e-15 55.6 0.1 5.5e-15 55.3 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ86329.1 - 0.0016 17.5 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CDJ86329.1 - 0.0021 16.9 0.1 0.0036 16.1 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Seadorna_VP7 PF07387.11 CDJ86329.1 - 0.01 15.0 0.1 0.016 14.3 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 CDJ86329.1 - 0.011 15.1 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 CDJ86329.1 - 0.029 14.3 0.0 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDJ86329.1 - 0.04 13.5 0.1 0.1 12.1 0.1 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase La PF05383.17 CDJ86329.1 - 0.12 12.4 0.1 16 5.6 0.0 2.4 2 0 0 2 2 2 0 La domain TPR_12 PF13424.6 CDJ86330.1 - 6.1e-12 45.7 0.3 3.3e-06 27.3 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat zf-MYND PF01753.18 CDJ86330.1 - 6.1e-06 26.2 11.0 6.1e-06 26.2 11.0 3.2 2 1 1 3 3 2 1 MYND finger TPR_10 PF13374.6 CDJ86330.1 - 8.3e-05 22.3 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ86330.1 - 0.0005 19.8 0.2 0.0012 18.6 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat CLTH PF10607.9 CDJ86330.1 - 0.011 15.6 0.5 3 7.7 0.2 2.3 2 0 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain TPR_2 PF07719.17 CDJ86330.1 - 0.018 15.1 0.1 0.045 13.9 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ86330.1 - 0.02 15.1 0.1 0.058 13.6 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat CYLD_phos_site PF16607.5 CDJ86330.1 - 0.024 14.5 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Phosphorylation region of CYLD, unstructured NuiA PF07924.11 CDJ86330.1 - 0.03 14.7 0.0 0.26 11.7 0.0 2.2 2 0 0 2 2 2 0 Nuclease A inhibitor-like protein zf-C3HC PF07967.13 CDJ86330.1 - 0.049 13.7 6.1 1.7 8.7 1.5 2.7 2 0 0 2 2 2 0 C3HC zinc finger-like PhnA_Zn_Ribbon PF08274.12 CDJ86330.1 - 3.2 7.8 7.7 0.54 10.3 1.3 3.0 2 1 0 2 2 2 0 PhnA Zinc-Ribbon PI3_PI4_kinase PF00454.27 CDJ86331.1 - 6.4e-14 52.4 0.0 8.3e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Nuc_sug_transp PF04142.15 CDJ86331.1 - 0.02 14.0 0.0 0.028 13.6 0.0 1.1 1 0 0 1 1 1 0 Nucleotide-sugar transporter CENP-F_leu_zip PF10473.9 CDJ86332.1 - 6.8e-06 26.1 116.4 0.003 17.6 14.5 5.9 1 1 4 5 5 5 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 CDJ86332.1 - 0.0015 19.0 34.2 0.0015 19.0 34.2 4.3 1 1 3 4 4 4 1 Fez1 DUF1664 PF07889.12 CDJ86332.1 - 0.002 18.1 7.7 0.002 18.1 7.7 7.2 1 1 7 8 8 8 4 Protein of unknown function (DUF1664) ERM PF00769.19 CDJ86332.1 - 0.0048 16.7 19.8 0.0048 16.7 19.8 4.4 1 1 3 4 4 4 2 Ezrin/radixin/moesin family APG6_N PF17675.1 CDJ86332.1 - 0.013 16.0 123.2 0.034 14.7 8.8 6.2 1 1 4 5 5 5 0 Apg6 coiled-coil region ATG16 PF08614.11 CDJ86332.1 - 0.052 13.8 121.6 1.2 9.3 31.6 5.6 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 CDJ86332.1 - 1.2 9.2 118.3 0.016 15.3 21.7 6.3 2 2 4 6 6 5 0 TPR/MLP1/MLP2-like protein DUF3584 PF12128.8 CDJ86332.1 - 1.6 6.1 101.8 0.52 7.8 22.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 CDJ86332.1 - 2.5 6.9 110.0 2.1 7.1 31.3 5.1 1 1 4 5 5 5 0 Spc7 kinetochore protein HOOK PF05622.12 CDJ86332.1 - 5.3 5.1 109.7 5.7 4.9 46.7 4.5 1 1 1 3 3 3 0 HOOK protein ADIP PF11559.8 CDJ86332.1 - 7.3 6.7 119.4 0.029 14.5 10.5 6.5 1 1 5 7 7 6 0 Afadin- and alpha -actinin-Binding PI3_PI4_kinase PF00454.27 CDJ86333.1 - 2.3e-26 93.1 0.0 4.5e-26 92.2 0.0 1.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF641 PF04859.12 CDJ86333.1 - 0.051 13.9 0.0 0.11 12.8 0.0 1.6 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF2890 PF11081.8 CDJ86333.1 - 1.1 9.3 5.0 0.63 10.1 2.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) EF-hand_1 PF00036.32 CDJ86334.1 - 3.7e-19 66.8 8.9 0.0055 16.2 0.1 6.6 6 0 0 6 6 6 5 EF hand EF-hand_7 PF13499.6 CDJ86334.1 - 5.2e-18 65.3 15.0 4.7e-07 30.1 0.7 3.9 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CDJ86334.1 - 6e-18 63.2 8.4 0.00041 20.0 0.1 5.9 6 0 0 6 6 6 4 EF-hand domain EF-hand_5 PF13202.6 CDJ86334.1 - 2e-13 49.1 18.1 0.0075 15.7 0.8 5.8 6 0 0 6 6 6 4 EF hand EF-hand_8 PF13833.6 CDJ86334.1 - 1e-07 31.7 11.3 0.45 10.4 0.0 5.9 6 0 0 6 6 6 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ86334.1 - 0.026 14.8 5.6 2 8.7 0.1 3.4 2 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 CDJ86334.1 - 0.16 11.8 2.0 1.2 9.0 0.0 3.3 4 2 1 5 5 5 0 EF hand EF-hand_4 PF12763.7 CDJ86334.1 - 3.5 7.6 7.6 8.6 6.4 0.1 4.2 3 2 2 5 5 5 0 Cytoskeletal-regulatory complex EF hand EB PF01683.18 CDJ86335.1 - 4.2e-09 36.6 7.6 4.2e-09 36.6 7.6 3.1 1 1 1 2 2 2 1 EB module Lustrin_cystein PF14625.6 CDJ86335.1 - 0.072 13.5 3.8 0.072 13.5 3.8 3.9 3 1 1 4 4 4 0 Lustrin, cysteine-rich repeated domain DUF5066 PF16728.5 CDJ86337.1 - 0.045 13.1 0.1 0.045 13.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5066) DUF2674 PF10879.8 CDJ86338.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2674) DUF1011 PF06237.12 CDJ86339.1 - 1.6e-15 57.2 3.4 1.6e-15 57.2 3.4 3.0 3 1 1 4 4 4 1 Protein of unknown function (DUF1011) SH3_9 PF14604.6 CDJ86341.1 - 2.8e-07 30.3 0.0 6.7e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CDJ86341.1 - 0.00039 20.0 0.0 0.00082 19.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DivIVA PF05103.13 CDJ86341.1 - 0.018 15.2 1.9 0.031 14.4 1.9 1.4 1 0 0 1 1 1 0 DivIVA protein SH3_1 PF00018.28 CDJ86341.1 - 0.028 14.0 0.0 0.067 12.8 0.0 1.7 1 0 0 1 1 1 0 SH3 domain DUF1599 PF07659.11 CDJ86341.1 - 0.19 12.2 0.1 0.64 10.5 0.1 1.9 1 0 0 1 1 1 0 Nucleotide modification associated domain 1 ABC_tran PF00005.27 CDJ86342.1 - 2.8e-48 163.9 0.0 6.4e-28 98.0 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CDJ86342.1 - 4.2e-28 98.5 30.2 2.6e-25 89.3 15.8 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 CDJ86342.1 - 2.6e-19 70.1 3.1 2.2e-05 24.4 0.0 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CDJ86342.1 - 2.5e-06 28.1 4.5 0.035 14.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 CDJ86342.1 - 5.6e-05 22.8 1.5 0.11 12.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 CDJ86342.1 - 0.00022 20.8 1.1 0.096 12.1 0.4 3.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CDJ86342.1 - 0.0028 17.7 0.0 4.1 7.5 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ86342.1 - 0.013 15.4 0.4 0.67 9.8 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_15 PF13175.6 CDJ86342.1 - 0.018 14.7 0.2 9.2 5.9 0.1 3.1 3 0 0 3 3 3 0 AAA ATPase domain SbcCD_C PF13558.6 CDJ86342.1 - 0.023 14.9 0.0 18 5.6 0.0 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 CDJ86342.1 - 0.033 13.4 0.0 3.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.22 CDJ86342.1 - 0.05 13.2 1.5 4.2 7.0 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_27 PF13514.6 CDJ86342.1 - 0.19 11.3 0.2 8.6 5.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 CDJ86342.1 - 0.27 11.0 2.5 2.3 7.9 0.2 2.3 2 0 0 2 2 2 0 MukB N-terminal AAA_30 PF13604.6 CDJ86342.1 - 1.7 8.3 3.3 11 5.7 0.2 2.7 2 1 0 2 2 2 0 AAA domain Helicase_C PF00271.31 CDJ86344.1 - 2e-12 47.4 4.1 1.3e-11 44.8 0.1 3.9 3 2 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ86344.1 - 3.8e-11 43.1 0.0 3.8e-11 43.1 0.0 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase Homeodomain PF00046.29 CDJ86345.1 - 2.4e-23 81.7 2.8 3.9e-23 81.1 2.8 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ86345.1 - 0.0082 16.0 0.1 0.019 14.9 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain RhoGEF67_u1 PF16615.5 CDJ86345.1 - 0.071 13.6 0.3 0.071 13.6 0.3 2.6 2 1 1 3 3 2 0 Unstructured region one on RhoGEF 6 and 7 DNA_pol_B PF00136.21 CDJ86346.1 - 4.5e-56 190.5 0.0 6.7e-56 189.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CDJ86346.1 - 2.4e-16 59.8 0.1 5.3e-10 39.0 0.2 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.13 CDJ86346.1 - 0.14 11.0 0.1 0.24 10.2 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Pkinase PF00069.25 CDJ86347.1 - 8e-45 153.2 0.0 1.1e-44 152.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ86347.1 - 4.8e-24 85.0 0.0 6.3e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ86347.1 - 0.00089 19.2 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ86347.1 - 0.0081 15.0 0.0 1.7 7.3 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase Kinase-like PF14531.6 CDJ86347.1 - 0.0081 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 CDJ86347.1 - 0.07 12.7 0.0 0.22 11.0 0.1 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase ShK PF01549.24 CDJ86348.1 - 2.4e-05 24.8 4.0 6.9e-05 23.3 4.0 1.9 1 1 0 1 1 1 1 ShK domain-like Aa_trans PF01490.18 CDJ86349.1 - 7.1e-20 71.1 11.7 3.3e-19 68.9 10.3 2.1 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Collagen PF01391.18 CDJ86350.1 - 1.6e-22 79.0 90.5 7.7e-08 32.0 35.8 4.2 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ86350.1 - 4.3e-12 45.9 0.8 6.1e-12 45.4 0.8 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain DUF3481 PF11980.8 CDJ86350.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein CaKB PF03185.15 CDJ86351.1 - 0.0064 16.2 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 Calcium-activated potassium channel, beta subunit N2227 PF07942.12 CDJ86351.1 - 0.18 10.9 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein Pox_A12 PF04651.13 CDJ86352.1 - 0.019 15.1 0.6 0.025 14.6 0.6 1.2 1 0 0 1 1 1 0 Poxvirus A12 protein DTHCT PF08070.11 CDJ86352.1 - 0.03 15.1 1.6 0.03 15.1 1.6 1.7 2 0 0 2 2 2 0 DTHCT (NUC029) region DUF1180 PF06679.12 CDJ86352.1 - 1.4 9.3 0.0 1.4 9.3 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) G-alpha PF00503.20 CDJ86353.1 - 1.6e-125 419.0 1.8 1.9e-125 418.8 1.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDJ86353.1 - 5.4e-18 65.0 0.1 3.4e-13 49.4 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ86353.1 - 3.3e-05 23.3 1.9 0.0062 15.9 0.5 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 CDJ86353.1 - 0.00041 20.6 0.4 1.1 9.5 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 CDJ86353.1 - 0.0068 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein Fam20C PF06702.12 CDJ86353.1 - 0.04 13.8 0.1 0.068 13.0 0.1 1.3 1 0 0 1 1 1 0 Golgi casein kinase, C-terminal, Fam20 FtsK_SpoIIIE PF01580.18 CDJ86353.1 - 0.088 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Ras PF00071.22 CDJ86353.1 - 0.11 12.1 0.5 9.4 5.8 0.2 2.4 2 0 0 2 2 2 0 Ras family MMR_HSR1 PF01926.23 CDJ86353.1 - 0.12 12.5 0.0 4.2 7.5 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 CDJ86353.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain UDPGT PF00201.18 CDJ86355.1 - 9.1e-54 183.1 0.5 1.1e-53 182.7 0.5 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ86355.1 - 2.4e-08 34.1 0.0 4e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Pkinase PF00069.25 CDJ86356.1 - 2.1e-73 247.0 0.0 3.6e-73 246.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ86356.1 - 6.3e-41 140.4 0.0 9e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ86356.1 - 3.9e-05 23.1 0.0 0.00013 21.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CDJ86356.1 - 0.00057 19.9 1.3 0.0021 18.0 0.1 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDJ86356.1 - 0.0038 16.2 0.5 0.0073 15.3 0.5 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CDJ86356.1 - 0.0062 15.9 0.2 0.015 14.7 0.2 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CDJ86356.1 - 0.009 15.6 0.3 0.019 14.5 0.3 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase YcxB PF14317.6 CDJ86356.1 - 0.065 12.9 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 YcxB-like protein GTP_EFTU PF00009.27 CDJ86357.1 - 1.7e-49 168.0 0.4 2.2e-49 167.6 0.4 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDJ86357.1 - 0.0028 17.7 0.1 0.02 15.0 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ86357.1 - 0.038 13.5 1.0 0.062 12.8 0.4 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF4089 PF13318.6 CDJ86358.1 - 0.021 15.3 0.2 0.055 13.9 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4089) Cadherin_C_2 PF16492.5 CDJ86358.1 - 0.15 12.8 0.3 0.32 11.8 0.3 1.6 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Endosulfine PF04667.17 CDJ86359.1 - 8e-15 54.7 3.0 1.3e-14 54.0 3.0 1.6 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region RBM39linker PF15519.6 CDJ86359.1 - 0.054 14.6 1.5 0.094 13.8 1.5 1.7 1 1 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein Ig_2 PF13895.6 CDJ86360.1 - 1e-17 64.2 0.0 5.4e-11 42.7 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 CDJ86360.1 - 3e-17 62.5 0.0 6.6e-10 38.9 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ86360.1 - 3.3e-16 59.7 0.0 1.1e-09 38.7 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 CDJ86360.1 - 7.4e-12 45.3 0.0 0.00016 21.8 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 CDJ86360.1 - 2.8e-09 37.1 0.0 0.00012 22.2 0.0 3.2 2 1 1 3 3 3 2 Immunoglobulin V-set domain Izumo-Ig PF16706.5 CDJ86360.1 - 7.4e-05 22.7 0.0 0.00029 20.8 0.0 1.9 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 CDJ86360.1 - 0.00016 22.0 0.0 0.063 13.7 0.0 2.3 2 0 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 CDJ86360.1 - 0.00095 18.7 0.0 0.23 11.1 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain Ig_4 PF16680.5 CDJ86360.1 - 0.0056 16.9 0.0 3.9 7.8 0.0 2.8 2 1 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 CDJ86360.1 - 0.044 13.8 0.0 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.11 CDJ86360.1 - 0.065 13.2 0.0 4.4 7.3 0.0 2.4 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain TMEM154 PF15102.6 CDJ86360.1 - 0.26 11.2 1.1 0.5 10.3 1.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family T2SSF PF00482.23 CDJ86360.1 - 0.6 10.1 2.2 1.2 9.1 2.2 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F MARVEL PF01284.23 CDJ86361.1 - 1.1e-06 28.8 11.2 1.5e-06 28.3 11.2 1.2 1 0 0 1 1 1 1 Membrane-associating domain 7TM_GPCR_Srsx PF10320.9 CDJ86362.1 - 2.2e-41 142.0 38.6 3.2e-41 141.4 38.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 CDJ86362.1 - 9.6e-08 31.7 35.5 9.6e-08 31.7 35.5 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) UPF0183 PF03676.14 CDJ86363.1 - 6.5e-36 124.5 0.1 8e-36 124.2 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) SdrD_B PF17210.3 CDJ86363.1 - 0.069 13.4 0.0 0.085 13.1 0.0 1.3 1 0 0 1 1 1 0 SdrD B-like domain Actin_micro PF17003.5 CDJ86364.1 - 0.0035 16.6 3.6 0.082 12.1 0.0 3.4 2 1 1 3 3 3 2 Putative actin-like family GP67 PF17634.2 CDJ86365.1 - 0.24 11.8 8.6 0.74 10.3 1.6 2.3 2 0 0 2 2 2 0 Gene product 67 PPL5 PF18168.1 CDJ86365.1 - 1.4 8.1 8.4 0.15 11.4 0.8 2.4 2 0 0 2 2 2 0 Prim-pol family 5 RPA_interact_C PF14768.6 CDJ86366.1 - 7.1e-08 32.9 2.8 7.1e-08 32.9 2.8 1.6 2 0 0 2 2 2 1 Replication protein A interacting C-terminal RPA_interact_N PF14766.6 CDJ86366.1 - 4.1e-05 23.1 4.9 0.00019 21.0 5.5 1.8 2 0 0 2 2 2 1 Replication protein A interacting N-terminal Zn_Tnp_IS1595 PF12760.7 CDJ86366.1 - 0.0091 15.9 1.5 2.4 8.2 0.2 2.5 2 0 0 2 2 2 2 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.6 CDJ86366.1 - 0.036 14.0 3.6 6.8 6.7 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain IBR PF01485.21 CDJ86366.1 - 0.069 13.4 0.9 1.4 9.2 0.1 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain eIF-5_eIF-2B PF01873.17 CDJ86366.1 - 0.1 12.4 1.1 1 9.2 0.0 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 NleF_casp_inhib PF16809.5 CDJ86366.1 - 0.14 12.1 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 NleF caspase inhibitor Pkinase PF00069.25 CDJ86368.1 - 1.7e-57 194.8 0.0 1.9e-57 194.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ86368.1 - 2.1e-35 122.3 0.0 2.7e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ86368.1 - 0.00059 18.9 0.9 0.00083 18.4 0.9 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CDJ86368.1 - 0.0044 15.9 0.0 0.0084 14.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDJ86368.1 - 0.021 14.1 0.0 0.049 13.0 0.0 1.7 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 CDJ86368.1 - 0.054 13.4 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DSPc PF00782.20 CDJ86369.1 - 1.1e-32 112.6 0.0 5.2e-32 110.4 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDJ86369.1 - 9.5e-05 22.1 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CDJ86369.1 - 0.016 15.3 0.1 0.037 14.2 0.0 1.6 2 0 0 2 2 2 0 Inositol hexakisphosphate CDKN3 PF05706.12 CDJ86369.1 - 0.094 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Glyco_hydro_108 PF05838.12 CDJ86369.1 - 0.12 12.9 0.0 0.73 10.3 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase 108 DUF4453 PF14627.6 CDJ86369.1 - 0.15 12.1 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) PP2C PF00481.21 CDJ86370.1 - 4.2e-53 180.6 0.0 6.1e-53 180.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CDJ86370.1 - 0.0036 17.0 0.0 0.2 11.3 0.0 2.8 2 1 1 3 3 3 1 Protein phosphatase 2C BTB PF00651.31 CDJ86371.1 - 4.7e-17 62.2 0.4 9.2e-17 61.3 0.4 1.5 1 0 0 1 1 1 1 BTB/POZ domain Asp PF00026.23 CDJ86372.1 - 5.4e-88 295.4 2.7 6.7e-88 295.1 2.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ86372.1 - 1.5e-10 41.6 7.2 9.1e-10 39.1 7.2 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ86372.1 - 0.0006 19.6 0.0 0.0029 17.4 0.0 2.1 1 1 1 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CDJ86372.1 - 0.0024 18.4 0.0 4.3 8.1 0.0 3.1 3 0 0 3 3 3 2 Aspartyl protease ABC_tran_CTD PF16326.5 CDJ86373.1 - 0.12 12.7 2.9 1.6 9.0 0.5 2.4 1 1 1 2 2 2 0 ABC transporter C-terminal domain TF_AP-2 PF03299.14 CDJ86374.1 - 3.9e-49 167.3 0.0 5.4e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 Transcription factor AP-2 DUF4236 PF14020.6 CDJ86374.1 - 0.12 13.0 0.0 0.29 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4236) Guanylate_cyc PF00211.20 CDJ86375.1 - 4.2e-46 156.9 0.0 1.9e-45 154.7 0.0 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Pkinase PF00069.25 CDJ86375.1 - 3.4e-16 59.4 0.0 7.7e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ86375.1 - 4.2e-15 55.7 0.0 8.8e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HNOBA PF07701.14 CDJ86375.1 - 0.00093 18.7 1.0 0.0018 17.8 1.0 1.4 1 0 0 1 1 1 1 Heme NO binding associated Helicase_C PF00271.31 CDJ86376.1 - 4.6e-32 110.7 0.0 6.1e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CDJ86376.1 - 0.0084 15.3 0.0 0.01 15.1 0.0 1.1 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Fanconi_A PF03511.14 CDJ86376.1 - 0.085 12.8 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Fanconi anaemia group A protein DEAD PF00270.29 CDJ86377.1 - 1.7e-17 63.8 0.1 2.1e-17 63.5 0.1 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 CDJ86377.1 - 0.0013 18.5 0.0 0.0015 18.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CDJ86377.1 - 0.0058 16.6 0.0 0.0074 16.3 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CDJ86377.1 - 0.0061 16.9 0.0 0.0079 16.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 CDJ86377.1 - 0.17 11.4 0.1 0.22 11.0 0.1 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Motile_Sperm PF00635.26 CDJ86378.1 - 3.3e-29 100.9 0.1 5.5e-29 100.2 0.1 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 CDJ86378.1 - 0.015 15.5 0.5 0.031 14.5 0.1 1.8 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin EpuA PF11772.8 CDJ86378.1 - 1.1 9.0 5.3 1.9 8.2 5.3 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Mito_carr PF00153.27 CDJ86379.1 - 1.8e-65 216.9 2.8 4.7e-23 80.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Sugar_tr PF00083.24 CDJ86380.1 - 2.1e-51 175.2 18.1 2.4e-51 175.0 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ86380.1 - 7.6e-23 81.0 13.0 7.6e-23 81.0 13.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 CDJ86380.1 - 0.011 14.1 3.3 0.023 13.1 3.3 1.5 1 0 0 1 1 1 0 Transmembrane secretion effector Phage_holin_3_2 PF04550.12 CDJ86380.1 - 0.062 13.8 0.7 0.062 13.8 0.7 2.5 3 0 0 3 3 3 0 Phage holin family 2 Ephrin PF00812.17 CDJ86381.1 - 3e-29 101.8 0.0 4.3e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Ephrin TcpQ PF10671.9 CDJ86381.1 - 0.04 14.0 0.0 0.079 13.1 0.0 1.6 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q Phosphodiest PF01663.22 CDJ86382.1 - 2.4e-51 175.4 2.7 3.1e-51 175.1 2.7 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CDJ86382.1 - 4.1e-05 23.1 0.0 0.00061 19.3 0.0 2.4 2 1 0 2 2 2 1 Sulfatase DUF4926 PF16277.5 CDJ86382.1 - 0.02 14.2 0.1 0.047 13.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4926) Metalloenzyme PF01676.18 CDJ86382.1 - 0.26 10.6 0.4 0.41 10.0 0.4 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily PX PF00787.24 CDJ86383.1 - 2.1e-13 50.2 0.3 3.1e-13 49.7 0.3 1.2 1 0 0 1 1 1 1 PX domain CECR6_TMEM121 PF14997.6 CDJ86384.1 - 2.3e-51 174.4 8.1 2.3e-51 174.4 8.1 1.7 2 1 0 2 2 2 1 CECR6/TMEM121 family Abhydrolase_9_N PF15420.6 CDJ86384.1 - 0.39 10.7 4.4 0.18 11.8 1.6 1.8 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Recep_L_domain PF01030.24 CDJ86385.1 - 1.3e-10 41.4 0.3 4.9e-10 39.5 0.1 1.9 2 0 0 2 2 2 1 Receptor L domain Peptidase_M41 PF01434.18 CDJ86387.1 - 1e-60 204.9 0.0 1.6e-60 204.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CDJ86387.1 - 1e-35 123.0 0.1 1.8e-34 119.0 0.0 3.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ86387.1 - 7e-10 38.5 0.0 2e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain 7TM_GPCR_Srh PF10318.9 CDJ86387.1 - 8e-07 28.4 8.8 1.1e-06 27.9 8.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh AAA_16 PF13191.6 CDJ86387.1 - 0.00026 21.4 0.0 0.00078 19.9 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CDJ86387.1 - 0.00037 20.5 0.1 0.0016 18.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 CDJ86387.1 - 0.00082 19.8 0.1 0.002 18.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CDJ86387.1 - 0.0019 18.3 0.0 0.0046 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDJ86387.1 - 0.0027 18.0 0.0 0.065 13.5 0.0 2.6 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 CDJ86387.1 - 0.0048 16.2 0.0 0.0076 15.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain 7TM_GPCR_Sri PF10327.9 CDJ86387.1 - 0.0053 16.0 8.3 0.009 15.2 8.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri AAA_18 PF13238.6 CDJ86387.1 - 0.014 15.9 0.1 0.055 14.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain 7TM_GPCR_Str PF10326.9 CDJ86387.1 - 0.017 14.4 8.3 0.03 13.7 8.3 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str RuvB_N PF05496.12 CDJ86387.1 - 0.022 14.5 0.0 0.058 13.1 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 CDJ86387.1 - 0.026 14.2 0.0 0.062 13.0 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain FtsH_ext PF06480.15 CDJ86387.1 - 0.026 14.9 0.1 0.12 12.8 0.0 2.1 2 0 0 2 2 2 0 FtsH Extracellular Mg_chelatase PF01078.21 CDJ86387.1 - 0.027 13.9 0.1 0.053 12.9 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI 7TM_GPCR_Srd PF10317.9 CDJ86387.1 - 0.034 13.3 6.1 0.067 12.4 6.1 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd AAA_28 PF13521.6 CDJ86387.1 - 0.035 14.3 0.1 0.082 13.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CDJ86387.1 - 0.042 13.8 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain IstB_IS21 PF01695.17 CDJ86387.1 - 0.049 13.3 0.1 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF2621 PF11084.8 CDJ86387.1 - 0.078 12.9 0.8 0.14 12.1 0.1 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF2621) AAA_14 PF13173.6 CDJ86387.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CDJ86387.1 - 0.13 12.6 0.0 0.41 11.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase SUIM_assoc PF16619.5 CDJ86388.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF2461 PF09365.10 CDJ86390.1 - 0.044 13.7 0.4 0.084 12.8 0.4 1.6 1 1 0 1 1 1 0 Conserved hypothetical protein (DUF2461) TetR_C_11 PF16859.5 CDJ86390.1 - 0.22 11.9 2.1 0.37 11.1 2.1 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain RVT_1 PF00078.27 CDJ86391.1 - 3.7e-25 88.7 0.0 6.4e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Acyltransferase PF01553.21 CDJ86392.1 - 3.1e-13 49.5 0.0 2e-12 46.9 0.0 2.2 2 0 0 2 2 2 1 Acyltransferase Leu_zip PF15294.6 CDJ86394.1 - 1.6e-05 24.6 39.9 2.5e-05 24.0 17.9 2.3 1 1 0 2 2 2 2 Leucine zipper DUF1192 PF06698.11 CDJ86394.1 - 0.0018 18.3 0.4 0.0018 18.3 0.4 4.8 4 1 1 5 5 5 2 Protein of unknown function (DUF1192) Sipho_Gp157 PF05565.11 CDJ86394.1 - 0.0022 18.0 2.8 0.0022 18.0 2.8 3.7 1 1 3 4 4 4 1 Siphovirus Gp157 TACC_C PF05010.14 CDJ86394.1 - 0.013 15.3 11.7 0.013 15.3 11.7 3.2 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ADIP PF11559.8 CDJ86394.1 - 0.77 9.8 46.1 0.17 12.0 4.9 4.6 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding FlxA PF14282.6 CDJ86394.1 - 1.1 9.3 37.0 4.6 7.3 4.1 5.3 1 1 5 6 6 6 0 FlxA-like protein GAS PF13851.6 CDJ86394.1 - 1.7 7.9 46.1 0.016 14.5 12.4 3.6 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF5082 PF16888.5 CDJ86394.1 - 3.5 7.9 30.0 0.1 12.9 3.6 4.4 1 1 3 4 4 4 0 Domain of unknown function (DUF5082) DUF1664 PF07889.12 CDJ86394.1 - 3.7 7.6 25.4 0.32 11.0 0.8 3.8 2 2 0 3 3 3 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 CDJ86394.1 - 8.4 5.4 36.3 0.014 14.5 5.7 3.1 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 TFIIA_gamma_N PF02268.16 CDJ86396.1 - 6.2e-21 74.2 0.1 1.1e-20 73.4 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain WD40 PF00400.32 CDJ86396.1 - 4.9e-15 55.7 11.1 0.03 15.2 0.0 7.5 6 1 1 7 7 7 4 WD domain, G-beta repeat TFIIA_gamma_C PF02751.14 CDJ86396.1 - 1.5e-13 50.6 0.9 3.2e-13 49.6 0.9 1.6 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit ANAPC4_WD40 PF12894.7 CDJ86396.1 - 1.1e-11 44.8 0.0 0.13 12.6 0.0 5.4 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CDJ86396.1 - 0.00031 20.2 0.0 0.97 8.7 0.0 2.8 2 1 0 3 3 3 2 WD40-like domain Frtz PF11768.8 CDJ86396.1 - 0.005 15.2 0.0 2.1 6.6 0.0 2.4 1 1 1 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 CDJ86396.1 - 0.085 11.8 1.2 0.92 8.4 0.5 2.7 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain TFIIA_gamma_C PF02751.14 CDJ86397.1 - 9.6e-19 67.3 2.5 1.5e-18 66.7 2.5 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 CDJ86397.1 - 1.3e-18 66.7 0.1 2e-18 66.1 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain MarR_2 PF12802.7 CDJ86397.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 MarR family RGS PF00615.19 CDJ86398.1 - 7.1e-35 119.8 6.3 1.4e-18 67.3 0.7 3.0 3 0 0 3 3 3 2 Regulator of G protein signaling domain DUF4597 PF15366.6 CDJ86398.1 - 0.076 12.8 0.2 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) NNMT_PNMT_TEMT PF01234.17 CDJ86400.1 - 2.4e-77 259.6 0.0 2.6e-77 259.5 0.0 1.0 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_11 PF08241.12 CDJ86400.1 - 5.6e-05 23.7 0.0 0.0018 18.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ86400.1 - 0.0061 17.2 0.0 2.1 9.1 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ86400.1 - 0.05 14.4 0.0 0.17 12.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CDJ86400.1 - 0.12 11.9 0.0 5.4 6.5 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase small domain DUF1759 PF03564.15 CDJ86401.1 - 1.1e-18 67.6 0.4 4.7e-18 65.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) Asp_protease_2 PF13650.6 CDJ86401.1 - 3.2e-07 30.9 0.0 8.8e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ86401.1 - 8.6e-07 29.4 0.0 2.6e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 CDJ86401.1 - 3.7e-05 23.5 0.0 9.4e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) RVP PF00077.20 CDJ86401.1 - 0.0035 17.6 0.0 0.013 15.8 0.0 2.0 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ86401.1 - 0.024 14.5 0.0 0.068 13.0 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease DUF3160 PF11369.8 CDJ86401.1 - 0.092 11.2 0.6 0.15 10.5 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) cEGF PF12662.7 CDJ86402.1 - 0.021 14.7 0.9 0.06 13.3 0.9 1.7 1 0 0 1 1 1 0 Complement Clr-like EGF-like ATP1G1_PLM_MAT8 PF02038.16 CDJ86402.1 - 0.11 12.0 0.2 0.3 10.6 0.2 1.7 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family COX5B PF01215.19 CDJ86403.1 - 2.1e-12 46.9 0.0 3.4e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb BTB PF00651.31 CDJ86403.1 - 0.00069 19.8 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-HIT PF04438.16 CDJ86404.1 - 6.5e-08 32.3 7.7 1e-07 31.7 7.7 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 CDJ86404.1 - 1.4 9.0 6.7 2.7 8.2 6.7 1.4 1 0 0 1 1 1 0 MYND finger Fumble PF03630.14 CDJ86405.1 - 7.3e-117 390.2 0.4 8.7e-117 390.0 0.4 1.0 1 0 0 1 1 1 1 Fumble AXH PF08517.12 CDJ86407.1 - 7.8e-36 123.2 0.0 1.4e-35 122.3 0.0 1.4 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) Exo_endo_phos PF03372.23 CDJ86408.1 - 0.00076 19.1 0.0 0.0016 18.0 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CDJ86408.1 - 0.001 18.9 0.0 0.0021 17.9 0.0 1.5 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase DUF148 PF02520.17 CDJ86410.1 - 1.4e-07 31.6 5.0 1.6e-07 31.4 5.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 DUF1542 PF07564.11 CDJ86410.1 - 0.00063 19.8 1.1 0.022 14.8 0.1 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1542) Tam41_Mmp37 PF09139.11 CDJ86410.1 - 0.088 12.2 0.4 0.099 12.1 0.4 1.0 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial 7TM_GPCR_Srsx PF10320.9 CDJ86411.1 - 1.3e-06 28.0 10.1 1.5e-06 27.8 10.1 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DHHC PF01529.20 CDJ86411.1 - 2.4 8.2 6.7 2.3 8.3 5.2 1.7 2 0 0 2 2 2 0 DHHC palmitoyltransferase 7TM_GPCR_Srsx PF10320.9 CDJ86412.1 - 1e-12 48.0 6.0 1.2e-12 47.8 6.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Colicin_V PF02674.16 CDJ86412.1 - 0.0078 16.2 5.2 0.013 15.5 5.2 1.3 1 0 0 1 1 1 1 Colicin V production protein 7TM_GPCR_Srw PF10324.9 CDJ86412.1 - 0.057 12.7 7.6 0.22 10.8 7.6 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw FGGY_N PF00370.21 CDJ86413.1 - 1.8e-08 34.2 0.6 8.1e-08 32.1 0.6 2.0 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CDJ86413.1 - 0.063 13.0 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain RdRP PF05183.12 CDJ86413.1 - 0.075 11.7 0.1 0.19 10.4 0.1 1.5 1 1 0 1 1 1 0 RNA dependent RNA polymerase Peptidase_M20 PF01546.28 CDJ86414.1 - 4.1e-33 114.8 0.0 5.2e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CDJ86414.1 - 2e-13 50.2 0.0 3.2e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CDJ86414.1 - 0.0029 17.3 0.0 0.011 15.5 0.0 1.9 2 1 0 2 2 2 1 Peptidase family M28 CAP PF00188.26 CDJ86416.1 - 3.9e-07 31.0 0.8 5.5e-07 30.5 0.8 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CDJ86417.1 - 6.7e-17 62.5 4.1 9.2e-17 62.1 4.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CDJ86418.1 - 4.6e-17 63.0 4.1 6.4e-17 62.6 4.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Astacin PF01400.24 CDJ86422.1 - 1.4e-51 174.8 0.0 3.1e-51 173.7 0.0 1.6 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) CUB PF00431.20 CDJ86422.1 - 0.00036 20.8 0.2 0.00067 20.0 0.2 1.4 1 0 0 1 1 1 1 CUB domain Peptidase_M10 PF00413.24 CDJ86422.1 - 0.002 18.0 1.0 0.011 15.6 0.3 1.8 1 1 0 2 2 2 1 Matrixin Reprolysin_4 PF13583.6 CDJ86422.1 - 0.0042 16.8 0.1 0.0073 16.0 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 CDJ86422.1 - 0.031 14.8 0.0 0.071 13.6 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CDJ86422.1 - 0.047 13.8 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF4953 PF16313.5 CDJ86422.1 - 0.077 12.2 0.5 0.13 11.4 0.5 1.3 1 0 0 1 1 1 0 Met-zincin Peptidase_M66 PF10462.9 CDJ86422.1 - 0.095 11.6 0.1 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 EGF_2 PF07974.13 CDJ86422.1 - 5.1 7.6 11.5 12 6.4 11.5 1.7 1 0 0 1 1 1 0 EGF-like domain Astacin PF01400.24 CDJ86423.1 - 2.6e-05 23.9 0.1 7.4e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) CUB PF00431.20 CDJ86423.1 - 0.00053 20.3 0.1 0.0011 19.3 0.1 1.5 1 0 0 1 1 1 1 CUB domain ShK PF01549.24 CDJ86423.1 - 0.00079 19.9 4.5 0.0016 19.0 4.5 1.5 1 0 0 1 1 1 1 ShK domain-like Misat_Tub_SegII PF10644.9 CDJ86423.1 - 0.045 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain TPPK_C PF12555.8 CDJ86424.1 - 0.062 13.4 0.1 0.098 12.7 0.1 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Sugar_tr PF00083.24 CDJ86425.1 - 2.6e-35 122.2 16.6 4e-35 121.6 16.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ86425.1 - 2.4e-20 72.8 13.4 5.4e-16 58.5 4.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CDJ86425.1 - 8.5e-06 24.6 4.3 8.5e-06 24.6 4.3 2.6 3 0 0 3 3 3 1 MFS/sugar transport protein TRI12 PF06609.13 CDJ86425.1 - 8.5e-05 21.2 3.4 8.5e-05 21.2 3.4 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Romo1 PF10247.9 CDJ86425.1 - 0.045 14.1 1.3 0.045 14.1 1.3 2.7 2 1 1 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 DUF4807 PF16065.5 CDJ86425.1 - 0.053 13.2 0.4 0.11 12.1 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4807) Med9 PF07544.13 CDJ86425.1 - 0.41 10.8 5.4 0.74 9.9 5.4 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 SUZ PF12752.7 CDJ86426.1 - 0.057 14.2 0.5 0.19 12.5 0.1 2.2 1 1 1 2 2 2 0 SUZ domain Thioredoxin PF00085.20 CDJ86427.1 - 1.8e-18 66.4 0.0 3.3e-17 62.4 0.1 2.2 2 0 0 2 2 2 1 Thioredoxin QSOX_Trx1 PF18108.1 CDJ86427.1 - 4.5e-05 23.6 0.0 8.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 QSOX Trx-like domain Thioredoxin_8 PF13905.6 CDJ86427.1 - 0.00015 22.0 0.0 0.00062 20.0 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 CDJ86427.1 - 0.00087 18.7 0.3 0.0019 17.6 0.3 1.4 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 CDJ86427.1 - 0.0087 15.8 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 CDJ86427.1 - 0.012 15.4 0.1 0.018 14.7 0.1 1.3 1 0 0 1 1 1 0 Redoxin Thioredoxin_7 PF13899.6 CDJ86427.1 - 0.051 13.8 0.2 0.11 12.7 0.2 1.6 1 0 0 1 1 1 0 Thioredoxin-like TraF PF13728.6 CDJ86427.1 - 0.1 12.4 0.0 0.93 9.3 0.1 2.2 2 0 0 2 2 2 0 F plasmid transfer operon protein AhpC-TSA PF00578.21 CDJ86427.1 - 0.14 12.1 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 AhpC/TSA family Evr1_Alr PF04777.13 CDJ86428.1 - 4.4e-22 78.4 0.6 3.1e-21 75.7 0.4 2.2 2 1 0 2 2 2 1 Erv1 / Alr family FAD_SOX PF18371.1 CDJ86428.1 - 0.00014 22.1 0.0 0.0064 16.8 0.0 2.8 2 1 1 3 3 3 1 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Zn_Tnp_IS1595 PF12760.7 CDJ86428.1 - 0.021 14.8 1.3 6.8 6.8 0.1 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF563 PF04577.14 CDJ86428.1 - 0.05 13.7 1.6 0.11 12.7 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF563) DUF35_N PF12172.8 CDJ86428.1 - 0.16 11.9 1.6 0.4 10.6 1.6 1.7 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) PTPA PF03095.15 CDJ86429.1 - 1.1e-73 248.3 0.1 1.4e-73 248.0 0.1 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein zf-RING_4 PF14570.6 CDJ86430.1 - 0.00096 18.9 10.8 0.00096 18.9 10.8 3.4 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 CDJ86430.1 - 0.0019 18.0 9.6 0.0019 18.0 9.6 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ86430.1 - 0.0021 18.4 12.7 0.0021 18.4 12.7 3.3 2 1 1 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 CDJ86430.1 - 0.0022 17.9 9.3 0.0022 17.9 9.3 3.3 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDJ86430.1 - 0.0032 17.3 12.4 0.0032 17.3 12.4 3.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ86430.1 - 0.0038 17.4 7.4 0.0038 17.4 7.4 3.5 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CDJ86430.1 - 0.0059 16.5 11.8 0.0059 16.5 11.8 3.4 3 0 0 3 3 3 1 zinc-RING finger domain Homeodomain PF00046.29 CDJ86431.1 - 5.7e-23 80.5 3.5 9.1e-23 79.9 3.5 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ86431.1 - 0.00036 20.4 0.7 0.00061 19.6 0.7 1.5 1 1 0 1 1 1 1 Homeobox KN domain Engrail_1_C_sig PF10525.9 CDJ86431.1 - 0.00043 19.4 0.7 0.00076 18.6 0.7 1.4 1 0 0 1 1 1 1 Engrailed homeobox C-terminal signature domain CENP-B_N PF04218.13 CDJ86431.1 - 0.012 15.2 0.9 0.021 14.5 0.2 1.7 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 CDJ86431.1 - 0.03 14.6 0.4 0.051 13.9 0.2 1.6 1 1 0 1 1 1 0 Transposase HTH_26 PF13443.6 CDJ86431.1 - 0.12 12.8 0.1 2.2 8.8 0.0 2.2 1 1 1 2 2 2 0 Cro/C1-type HTH DNA-binding domain YdaS_antitoxin PF15943.5 CDJ86431.1 - 0.14 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT SOAR PF16533.5 CDJ86432.1 - 1e-30 105.7 0.5 1e-30 105.7 0.5 2.8 3 1 1 4 4 4 1 STIM1 Orai1-activating region RRM_1 PF00076.22 CDJ86432.1 - 3.5e-13 49.2 0.0 7.5e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAM_2 PF07647.17 CDJ86432.1 - 6e-05 23.1 0.1 0.00016 21.7 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CDJ86432.1 - 0.0047 17.3 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RRM_5 PF13893.6 CDJ86432.1 - 0.06 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_1 PF00036.32 CDJ86432.1 - 0.16 11.6 0.6 0.35 10.5 0.1 1.9 2 0 0 2 2 2 0 EF hand DivIC PF04977.15 CDJ86432.1 - 1.7 8.5 7.3 4.8 7.0 1.8 3.2 2 0 0 2 2 2 0 Septum formation initiator Hydrolase_3 PF08282.12 CDJ86433.1 - 0.0016 18.2 0.1 0.0055 16.5 0.1 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CDJ86433.1 - 0.0024 17.5 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Methyltransf_34 PF11312.8 CDJ86433.1 - 0.093 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Arf PF00025.21 CDJ86434.1 - 3.4e-66 222.0 0.1 3.8e-66 221.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ86434.1 - 9.2e-16 57.9 0.0 1.2e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 CDJ86434.1 - 6.9e-15 55.0 0.0 8.1e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ86434.1 - 1.6e-14 54.1 0.0 2.4e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CDJ86434.1 - 2.8e-13 49.8 1.8 3.4e-08 33.0 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CDJ86434.1 - 4.8e-12 45.7 0.0 5.8e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CDJ86434.1 - 2.6e-07 30.7 0.0 3.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 CDJ86434.1 - 8.8e-05 23.1 0.0 0.00014 22.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 CDJ86434.1 - 0.0042 16.6 0.0 0.019 14.5 0.0 1.7 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 CDJ86434.1 - 0.01 16.3 0.0 0.025 15.0 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 CDJ86434.1 - 0.016 14.7 0.4 0.061 12.9 0.4 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B 6PF2K PF01591.18 CDJ86434.1 - 0.05 12.9 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase PduV-EutP PF10662.9 CDJ86434.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Glyco_transf_20 PF00982.21 CDJ86436.1 - 2.2e-12 46.4 0.0 5.2e-10 38.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 20 DUF573 PF04504.14 CDJ86436.1 - 0.078 13.6 0.1 2.5 8.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF573 RVT_1 PF00078.27 CDJ86439.1 - 6.3e-15 55.3 0.0 1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CDJ86440.1 - 1.5e-14 54.1 0.0 2.4e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CDJ86440.1 - 0.00082 19.0 0.0 0.0019 17.8 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CDJ86440.1 - 0.0046 16.8 0.0 0.011 15.5 0.0 1.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase SCVP PF17619.2 CDJ86441.1 - 2.3e-23 82.8 0.4 2.7e-23 82.6 0.4 1.1 1 0 0 1 1 1 1 Secreted clade V proteins DUF2431 PF10354.9 CDJ86441.1 - 0.023 15.0 0.1 0.029 14.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Cys_rich_FGFR PF00839.17 CDJ86442.1 - 5.3e-131 426.8 75.6 6.5e-15 55.1 1.7 14.0 14 0 0 14 14 14 13 Cysteine rich repeat Arm_vescicular PF18770.1 CDJ86443.1 - 0.018 15.0 0.4 0.039 13.9 0.4 1.6 1 0 0 1 1 1 0 Armadillo tether-repeat of vescicular transport factor DUF2956 PF11169.8 CDJ86443.1 - 2.1 8.6 6.5 0.31 11.3 2.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) zf-RING_UBOX PF13445.6 CDJ86445.1 - 0.00013 21.9 5.6 0.00013 21.9 5.6 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDJ86445.1 - 0.00039 20.3 5.5 0.00039 20.3 5.5 2.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CDJ86445.1 - 0.00061 19.6 3.7 0.00061 19.6 3.7 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ86445.1 - 0.00082 19.2 5.4 0.00082 19.2 5.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ86445.1 - 0.0077 16.6 7.5 0.0077 16.6 7.5 2.5 1 1 1 2 2 2 1 Ring finger domain IBR PF01485.21 CDJ86445.1 - 0.043 14.0 7.5 2.7 8.3 0.0 3.1 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain DUF3110 PF11360.8 CDJ86445.1 - 0.073 13.3 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) zf-C3HC4_4 PF15227.6 CDJ86445.1 - 0.1 12.7 12.8 0.037 14.2 8.1 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CDJ86445.1 - 0.18 11.7 11.6 0.038 13.8 7.4 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 CDJ86445.1 - 0.29 11.3 5.7 0.57 10.4 5.7 1.5 1 0 0 1 1 1 0 B-box zinc finger zf-RING_11 PF17123.5 CDJ86445.1 - 3 7.6 13.6 0.21 11.3 6.3 2.5 2 0 0 2 2 2 0 RING-like zinc finger Secretogranin_V PF05281.11 CDJ86447.1 - 1.3e-40 139.4 1.1 1.5e-40 139.2 1.1 1.0 1 0 0 1 1 1 1 Neuroendocrine protein 7B2 precursor (Secretogranin V) NUDIX PF00293.28 CDJ86450.1 - 8.9e-13 48.4 0.0 1.6e-12 47.6 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain DUF4834 PF16118.5 CDJ86451.1 - 0.11 13.5 0.5 0.11 13.5 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) MMM1 PF10296.9 CDJ86451.1 - 0.27 10.3 2.5 0.16 11.0 0.3 1.6 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 Ndc1_Nup PF09531.10 CDJ86451.1 - 0.74 8.4 3.5 0.94 8.1 3.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4551 PF15087.6 CDJ86451.1 - 0.78 8.5 7.6 0.93 8.2 7.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CDC45 PF02724.14 CDJ86451.1 - 0.99 7.6 4.9 1.1 7.5 4.9 1.0 1 0 0 1 1 1 0 CDC45-like protein MGC-24 PF05283.11 CDJ86451.1 - 0.99 9.8 8.0 8.6 6.8 8.0 2.0 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin NPR3 PF03666.13 CDJ86451.1 - 1.7 7.4 5.5 1.8 7.3 5.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FKBP_C PF00254.28 CDJ86452.1 - 7.1e-14 51.9 0.0 1.5e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_7 PF13499.6 CDJ86452.1 - 6.3e-10 39.4 2.5 8.7e-08 32.5 0.6 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CDJ86452.1 - 7.3e-09 34.6 4.2 4.2e-06 25.9 0.7 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CDJ86452.1 - 5e-08 32.2 2.6 0.00023 20.9 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CDJ86452.1 - 1.4e-05 24.4 9.6 6.1e-05 22.3 0.1 3.5 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 CDJ86452.1 - 0.00012 21.8 0.4 0.28 11.0 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair Dockerin_1 PF00404.18 CDJ86452.1 - 0.0078 16.4 1.2 0.092 13.0 0.1 2.4 1 1 1 2 2 2 1 Dockerin type I domain DUF3872 PF12988.7 CDJ86452.1 - 0.012 15.4 0.1 0.023 14.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3872) MFS_1 PF07690.16 CDJ86453.1 - 1.8e-24 86.4 39.2 1.8e-24 86.4 39.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily gerPA PF10676.9 CDJ86453.1 - 0.11 12.8 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 Spore germination protein gerPA/gerPF MIF4G_like_2 PF09090.11 CDJ86454.1 - 3e-52 177.7 4.1 6.7e-52 176.6 4.1 1.6 1 0 0 1 1 1 1 MIF4G like MIF4G_like PF09088.11 CDJ86454.1 - 2.1e-28 99.4 0.1 5.6e-28 98.0 0.1 1.8 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.19 CDJ86454.1 - 1.6e-23 83.4 2.6 1.6e-23 83.4 2.6 1.9 2 0 0 2 2 2 1 MIF4G domain ELP6 PF09807.9 CDJ86454.1 - 3.3e-05 23.4 1.4 0.074 12.5 0.3 2.8 1 1 1 2 2 2 2 Elongation complex protein 6 DUF1978 PF09321.10 CDJ86454.1 - 0.02 14.2 6.8 0.044 13.1 6.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) DUF4303 PF14136.6 CDJ86454.1 - 0.068 12.9 0.1 0.59 9.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4303) DASH_Spc19 PF08287.11 CDJ86454.1 - 1.3 8.9 7.2 0.61 10.0 2.7 2.3 2 0 0 2 2 2 0 Spc19 tRNA-synt_1c PF00749.21 CDJ86455.1 - 3e-113 377.9 0.2 5.2e-113 377.1 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain WHEP-TRS PF00458.20 CDJ86455.1 - 2.9e-80 264.3 58.4 1e-17 64.0 2.3 5.4 5 0 0 5 5 5 5 WHEP-TRS domain tRNA-synt_1c_C PF03950.18 CDJ86455.1 - 8.6e-35 120.2 0.7 1.6e-34 119.3 0.2 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 CDJ86455.1 - 0.0026 17.1 0.0 0.0062 15.9 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Cullin PF00888.22 CDJ86455.1 - 0.047 12.3 19.4 1.6 7.2 0.2 5.3 4 1 1 5 5 5 0 Cullin family Nicastrin PF05450.15 CDJ86456.1 - 6.6e-44 150.1 0.0 1e-43 149.5 0.0 1.2 1 0 0 1 1 1 1 Nicastrin Ncstrn_small PF18266.1 CDJ86456.1 - 7.9e-39 133.4 0.0 1.2e-38 132.8 0.0 1.3 1 0 0 1 1 1 1 Nicastrin small lobe Peptidase_M28 PF04389.17 CDJ86456.1 - 0.028 14.1 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 Nicastrin PF05450.15 CDJ86457.1 - 7.2e-44 150.0 0.0 1.1e-43 149.4 0.0 1.3 1 0 0 1 1 1 1 Nicastrin Ncstrn_small PF18266.1 CDJ86457.1 - 5.4e-39 133.9 0.0 9.3e-39 133.1 0.0 1.4 1 0 0 1 1 1 1 Nicastrin small lobe zf-CSL PF05207.13 CDJ86457.1 - 0.11 12.2 4.2 0.57 9.9 1.2 2.4 1 1 1 2 2 2 0 CSL zinc finger Peptidase_M28 PF04389.17 CDJ86457.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 HRG PF16954.5 CDJ86457.1 - 5.7 7.4 7.2 16 6.0 1.2 2.8 2 0 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Peptidase_M14 PF00246.24 CDJ86459.1 - 5.7e-80 269.2 0.0 7.3e-80 268.9 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 CDJ86459.1 - 3.5e-15 56.1 0.1 4e-14 52.8 0.2 2.2 2 0 0 2 2 2 1 Carboxypeptidase activation peptide ShK PF01549.24 CDJ86459.1 - 0.00033 21.1 8.9 0.0007 20.1 8.9 1.6 1 0 0 1 1 1 1 ShK domain-like DUF2397 PF09660.10 CDJ86459.1 - 0.016 14.1 6.5 0.023 13.6 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) PRIMA1 PF16101.5 CDJ86459.1 - 0.029 14.4 8.5 0.064 13.3 8.5 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 CDJ86459.1 - 8.2 5.8 10.1 0.22 11.0 3.7 1.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal rve PF00665.26 CDJ86460.1 - 8.4e-22 77.6 0.0 1.8e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ86460.1 - 3.6e-07 30.2 1.9 9.5e-07 28.8 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve_3 PF13683.6 CDJ86460.1 - 7e-06 25.7 0.2 2.5e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain NHase_beta PF02211.15 CDJ86460.1 - 0.12 12.4 0.1 1 9.4 0.1 2.0 2 0 0 2 2 2 0 Nitrile hydratase beta subunit gag-asp_proteas PF13975.6 CDJ86461.1 - 1e-05 26.0 0.0 2.7e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ86461.1 - 0.0057 17.3 0.0 0.02 15.5 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ86461.1 - 0.01 16.1 0.0 0.03 14.6 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Tfb2_C PF18307.1 CDJ86462.1 - 3e-21 75.6 0.1 4.3e-21 75.1 0.1 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Tfb2 PF03849.14 CDJ86462.1 - 3.1e-12 46.1 0.0 3.8e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.6 CDJ86462.1 - 0.00019 21.6 0.0 0.00027 21.1 0.0 1.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Exog_C PF18026.1 CDJ86463.1 - 0.081 13.0 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Endo/exonuclease (EXOG) C-terminal domain Tfb2 PF03849.14 CDJ86464.1 - 4.6e-43 147.6 0.0 7.9e-43 146.8 0.0 1.4 1 0 0 1 1 1 1 Transcription factor Tfb2 CNOT11 PF10155.9 CDJ86464.1 - 1.3e-17 64.1 0.5 4e-17 62.5 0.1 2.0 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 11 DNase_II PF03265.15 CDJ86465.1 - 3.2e-54 184.4 1.0 3.9e-54 184.1 1.0 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II Ribonuc_L-PSP PF01042.21 CDJ86466.1 - 2.6e-25 88.8 0.3 2.8e-25 88.7 0.3 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Kunitz_BPTI PF00014.23 CDJ86467.1 - 3.7e-26 91.1 18.3 1.5e-16 60.3 6.4 2.3 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Kunitz_BPTI PF00014.23 CDJ86468.1 - 1.9e-15 56.8 7.8 1.9e-15 56.8 7.8 3.3 4 0 0 4 4 4 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Lustrin_cystein PF14625.6 CDJ86468.1 - 2.6 8.5 19.3 0.43 11.0 11.4 3.6 2 1 1 3 3 3 0 Lustrin, cysteine-rich repeated domain DUF3453 PF11935.8 CDJ86469.1 - 8.9e-51 172.7 1.0 8.9e-51 172.7 1.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Symplekin_C PF12295.8 CDJ86469.1 - 2.2e-26 93.1 3.0 3.7e-26 92.4 0.0 2.8 3 0 0 3 3 3 1 Symplekin tight junction protein C terminal Auts2 PF15336.6 CDJ86469.1 - 0.25 11.4 7.4 0.48 10.5 7.4 1.4 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein HS1_rep PF02218.15 CDJ86470.1 - 3.2e-111 363.3 57.2 1e-19 70.6 3.5 6.6 6 0 0 6 6 6 6 Repeat in HS1/Cortactin SH3_1 PF00018.28 CDJ86470.1 - 1.4e-07 31.0 0.7 3.9e-07 29.6 0.7 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CDJ86470.1 - 6.9e-05 22.6 0.1 0.00015 21.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain TMEM210 PF15195.6 CDJ86470.1 - 0.00016 22.1 2.9 64 4.0 0.1 5.9 1 1 5 6 6 6 0 TMEM210 family DUF3977 PF13122.6 CDJ86470.1 - 0.6 10.4 1.8 89 3.4 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF3977) DUF2407_C PF13373.6 CDJ86470.1 - 5.2 7.2 6.5 15 5.7 6.5 1.8 1 0 0 1 1 1 0 DUF2407 C-terminal domain CoaE PF01121.20 CDJ86471.1 - 7.2e-34 117.0 0.0 1.1e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 Dephospho-CoA kinase MTH865 PF07747.11 CDJ86471.1 - 0.069 12.9 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 MTH865-like family FARP PF01581.16 CDJ86472.1 - 0.00071 19.6 1.8 1.3 9.9 0.7 2.6 2 0 0 2 2 2 2 FMRFamide related peptide family RVT_1 PF00078.27 CDJ86473.1 - 4.5e-07 29.6 0.0 6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GDNF PF02351.16 CDJ86474.1 - 0.00013 22.9 28.4 0.018 16.0 11.8 2.4 2 0 0 2 2 2 2 GDNF/GAS1 domain DUF2576 PF10845.8 CDJ86474.1 - 0.058 13.0 0.8 0.15 11.7 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) RRM_1 PF00076.22 CDJ86475.1 - 1.8e-23 82.2 0.0 2e-23 82.0 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ86475.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif Pyr_redox_dim PF02852.22 CDJ86475.1 - 0.055 13.7 0.0 0.06 13.6 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain RRM_5 PF13893.6 CDJ86475.1 - 0.083 12.5 0.0 0.091 12.4 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GPP34 PF05719.11 CDJ86476.1 - 1.4e-56 191.7 0.1 1.9e-56 191.4 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Pkinase PF00069.25 CDJ86478.1 - 5.5e-62 209.5 0.0 6.6e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ86478.1 - 1.5e-41 142.4 0.0 1.8e-41 142.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ86478.1 - 3.5e-06 26.1 0.0 9.7e-05 21.3 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CDJ86478.1 - 6.6e-06 25.7 0.1 8.2e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CDJ86478.1 - 0.056 12.4 0.1 0.075 12.0 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 CDJ86478.1 - 0.067 12.8 0.4 0.17 11.5 0.2 1.8 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 CDJ86478.1 - 0.077 12.6 0.3 0.11 12.0 0.3 1.2 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 CDJ86478.1 - 0.15 11.4 0.2 0.22 10.8 0.2 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ86478.1 - 0.19 11.6 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family 7tm_1 PF00001.21 CDJ86479.1 - 1.8e-32 112.7 9.1 2.5e-32 112.2 9.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CDJ86479.1 - 3.7e-06 26.8 4.9 3.7e-06 26.8 4.9 1.8 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 CDJ86479.1 - 0.00023 20.6 3.2 0.00023 20.6 3.2 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 CDJ86479.1 - 0.005 16.3 9.0 0.14 11.5 0.7 2.4 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx Serpentine_r_xa PF03383.15 CDJ86479.1 - 0.021 14.8 0.1 0.021 14.8 0.1 2.0 3 0 0 3 3 3 0 Caenorhabditis serpentine receptor-like protein, class xa 7tm_4 PF13853.6 CDJ86479.1 - 0.022 14.5 1.1 0.045 13.5 1.1 1.4 1 0 0 1 1 1 0 Olfactory receptor Pkinase PF00069.25 CDJ86480.1 - 4.8e-24 85.1 0.7 5.8e-24 84.9 0.7 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ86480.1 - 1.7e-14 53.8 0.1 2e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ86480.1 - 1.4e-05 24.1 0.0 2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDJ86480.1 - 0.0014 18.6 0.0 0.0058 16.6 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family UspB PF10625.9 CDJ86480.1 - 0.35 10.8 2.6 3.3 7.7 0.4 2.2 2 0 0 2 2 2 0 Universal stress protein B (UspB) PNP_UDP_1 PF01048.20 CDJ86481.1 - 5.6e-29 101.1 0.0 6.6e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily MEIOC PF15189.6 CDJ86482.1 - 4e-63 212.0 2.3 6.5e-63 211.3 2.3 1.3 1 0 0 1 1 1 1 Meiosis-specific coiled-coil domain-containing protein MEIOC ALIX_LYPXL_bnd PF13949.6 CDJ86482.1 - 0.00015 21.1 2.7 0.0045 16.3 0.6 2.1 2 0 0 2 2 2 2 ALIX V-shaped domain binding to HIV DnaG_DnaB_bind PF08278.11 CDJ86482.1 - 0.029 14.9 1.6 0.029 14.9 1.6 2.4 2 1 0 2 2 2 0 DNA primase DnaG DnaB-binding TFIIA PF03153.13 CDJ86482.1 - 0.35 10.8 9.7 0.42 10.5 9.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DivIVA PF05103.13 CDJ86482.1 - 0.63 10.1 4.4 0.5 10.4 1.0 2.2 2 0 0 2 2 2 0 DivIVA protein DUF4600 PF15372.6 CDJ86482.1 - 1.4 9.3 9.3 0.45 10.9 5.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) MtN3_slv PF03083.16 CDJ86483.1 - 3.1e-48 161.7 10.2 9.2e-25 86.5 3.3 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Oxidored_q2 PF00420.24 CDJ86483.1 - 0.01 15.4 1.8 0.053 13.2 0.7 2.6 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L LAB_N PF07578.11 CDJ86483.1 - 0.11 12.6 2.6 3.1 8.0 0.4 2.6 2 0 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain HSP9_HSP12 PF04119.12 CDJ86484.1 - 0.37 11.2 4.3 4.5 7.7 0.2 2.7 2 1 0 2 2 2 0 Heat shock protein 9/12 HSP9_HSP12 PF04119.12 CDJ86486.1 - 0.16 12.3 4.3 4.5 7.7 0.2 2.9 2 1 0 2 2 2 0 Heat shock protein 9/12 DUF1798 PF08807.10 CDJ86487.1 - 0.0084 16.2 2.0 0.85 9.8 0.0 2.5 3 0 0 3 3 3 2 Bacterial domain of unknown function (DUF1798) Aldose_epim PF01263.20 CDJ86487.1 - 0.025 13.9 0.5 5 6.3 0.0 2.0 1 1 1 2 2 2 0 Aldose 1-epimerase PXT1 PF15214.6 CDJ86487.1 - 0.046 14.1 0.7 10 6.6 0.2 2.4 2 0 0 2 2 2 0 Peroxisomal testis-specific protein 1 HSP9_HSP12 PF04119.12 CDJ86487.1 - 0.88 10.0 3.7 9.9 6.6 0.2 2.7 2 1 0 2 2 2 0 Heat shock protein 9/12 Kringle PF00051.18 CDJ86488.1 - 2e-05 24.8 1.0 2e-05 24.8 1.0 1.8 2 0 0 2 2 2 1 Kringle domain Ribosomal_L6e_N PF03868.15 CDJ86488.1 - 0.017 15.4 3.0 0.042 14.1 3.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L6, N-terminal domain CAMSAP_CKK PF08683.11 CDJ86488.1 - 0.062 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Microtubule-binding calmodulin-regulated spectrin-associated Ank_2 PF12796.7 CDJ86489.1 - 1.5e-36 124.9 15.6 8.1e-12 45.6 0.2 6.0 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ86489.1 - 2.6e-28 98.0 11.6 3.2e-07 30.8 0.6 8.6 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ86489.1 - 2.9e-17 62.5 9.0 1e-08 35.3 0.2 7.7 3 3 6 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ86489.1 - 1.5e-15 55.7 16.0 0.022 15.3 0.1 10.9 12 0 0 12 12 11 3 Ankyrin repeat Ank PF00023.30 CDJ86489.1 - 2e-09 37.5 15.2 0.0088 16.5 0.1 9.1 10 0 0 10 10 10 2 Ankyrin repeat TPR_2 PF07719.17 CDJ86489.1 - 0.00038 20.4 1.6 0.032 14.3 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ86489.1 - 0.00075 19.7 1.7 0.0056 16.9 0.4 2.9 3 0 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CDJ86489.1 - 0.004 17.9 0.1 3.1 8.8 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat NACHT PF05729.12 CDJ86489.1 - 0.0046 16.9 0.1 0.15 12.0 0.0 2.9 3 0 0 3 3 3 1 NACHT domain TPR_12 PF13424.6 CDJ86489.1 - 0.0056 16.9 0.4 5.3 7.4 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ86489.1 - 0.0059 16.4 0.0 0.18 11.7 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ86489.1 - 0.014 15.6 0.0 0.21 11.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ86489.1 - 0.03 15.0 0.1 1.5 9.5 0.0 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat ATPase_2 PF01637.18 CDJ86489.1 - 0.065 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TPR_7 PF13176.6 CDJ86489.1 - 0.069 13.2 0.1 4.6 7.5 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ86489.1 - 0.075 13.7 0.0 46 4.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat CAP_GLY PF01302.25 CDJ86490.1 - 2.7e-49 165.0 2.0 1.7e-24 85.6 0.5 2.4 2 0 0 2 2 2 2 CAP-Gly domain CLIP1_ZNF PF16641.5 CDJ86490.1 - 4.4e-13 48.7 19.2 3.5e-08 33.1 4.2 2.3 2 0 0 2 2 2 2 CLIP1 zinc knuckle Tup_N PF08581.10 CDJ86490.1 - 0.011 16.0 14.1 0.011 16.0 14.1 14.6 9 6 5 15 15 15 0 Tup N-terminal Myosin_tail_1 PF01576.19 CDJ86491.1 - 0.00058 17.8 84.6 0.00058 17.8 84.6 2.3 1 1 1 2 2 2 1 Myosin tail AAA_13 PF13166.6 CDJ86491.1 - 0.0027 16.5 31.9 0.0027 16.5 31.9 5.2 1 1 4 5 5 5 3 AAA domain DHR10 PF18595.1 CDJ86491.1 - 0.011 15.8 12.2 0.011 15.8 12.2 9.0 1 1 8 10 10 10 0 Designed helical repeat protein 10 domain Aconitase PF00330.20 CDJ86493.1 - 8e-143 476.8 0.0 1.1e-142 476.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CDJ86493.1 - 1.7e-43 148.1 0.0 3.8e-43 147.0 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Myosin_head PF00063.21 CDJ86494.1 - 1.5e-228 760.4 3.7 1.7e-228 760.2 3.7 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 CDJ86494.1 - 5.8e-07 29.2 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 CDJ86494.1 - 0.05 14.0 0.0 0.16 12.3 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 CDJ86494.1 - 0.055 13.8 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CDJ86494.1 - 0.062 13.6 0.0 0.21 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF4537 PF15057.6 CDJ86494.1 - 0.1 12.6 0.3 5.2 7.1 0.0 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4537) Aldo_ket_red PF00248.21 CDJ86496.1 - 3.2e-44 151.3 0.0 5.9e-42 143.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_42C PF08533.10 CDJ86497.1 - 0.077 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase C-terminal domain LETM1 PF07766.13 CDJ86498.1 - 0.0006 19.2 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 LETM1-like protein TAFII28 PF04719.14 CDJ86499.1 - 1.7e-31 108.1 0.0 3.6e-31 107.1 0.0 1.6 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Ras PF00071.22 CDJ86500.1 - 8.5e-42 142.5 0.0 1.3e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ86500.1 - 6.8e-28 97.3 0.0 1.3e-27 96.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ86500.1 - 9.8e-13 47.9 0.0 2.3e-12 46.7 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ86500.1 - 4.2e-07 29.6 0.0 7.6e-07 28.7 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CDJ86500.1 - 0.00075 19.0 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CDJ86500.1 - 0.0047 16.1 0.1 0.036 13.2 0.1 2.4 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 CDJ86500.1 - 0.0052 16.9 0.0 0.0099 16.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Osteoregulin PF07175.11 CDJ86500.1 - 0.16 12.2 1.7 0.34 11.1 1.7 1.5 1 0 0 1 1 1 0 Osteoregulin EGF_CA PF07645.15 CDJ86501.1 - 7.3e-06 26.1 3.2 7.3e-06 26.1 3.2 4.6 5 1 1 6 6 6 2 Calcium-binding EGF domain cEGF PF12662.7 CDJ86501.1 - 0.0021 18.0 0.5 0.0021 18.0 0.5 4.3 4 0 0 4 4 4 1 Complement Clr-like EGF-like EGF_3 PF12947.7 CDJ86501.1 - 0.0087 16.2 23.2 0.21 11.8 2.3 3.7 3 0 0 3 3 3 2 EGF domain SEA PF01390.20 CDJ86501.1 - 0.031 14.4 0.1 0.044 13.9 0.1 1.2 1 0 0 1 1 1 0 SEA domain EGF_MSP1_1 PF12946.7 CDJ86501.1 - 0.042 13.9 1.4 0.042 13.9 1.4 3.5 3 1 1 4 4 4 0 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 CDJ86501.1 - 0.078 13.3 1.0 0.078 13.3 1.0 3.5 2 1 0 2 2 2 0 Pvs28 EGF domain Cadherin_C_2 PF16492.5 CDJ86501.1 - 0.092 13.5 0.1 0.17 12.7 0.1 1.4 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal hEGF PF12661.7 CDJ86501.1 - 4 8.2 16.0 10 6.9 1.7 4.1 3 0 0 3 3 3 0 Human growth factor-like EGF IFT81_CH PF18383.1 CDJ86502.1 - 1.1e-42 145.1 0.1 1.1e-42 145.1 0.1 3.1 3 1 1 4 4 4 1 Intraflagellar transport 81 calponin homology domain Spc7 PF08317.11 CDJ86502.1 - 0.00034 19.6 65.6 0.0047 15.8 17.3 4.4 2 1 3 5 5 5 4 Spc7 kinetochore protein MbeD_MobD PF04899.12 CDJ86502.1 - 0.005 16.9 7.5 0.005 16.9 7.5 5.4 6 1 0 6 6 6 1 MbeD/MobD like FliJ PF02050.16 CDJ86502.1 - 0.017 15.3 7.5 0.017 15.3 7.5 6.6 3 3 5 8 8 8 0 Flagellar FliJ protein LAGLIDADG_WhiA PF14527.6 CDJ86502.1 - 1.1 9.4 5.3 1.3 9.2 1.0 3.1 2 1 0 2 2 2 0 WhiA LAGLIDADG-like domain DUF1843 PF08898.10 CDJ86502.1 - 1.6 9.3 5.9 14 6.3 0.1 5.0 4 1 1 5 5 5 0 Domain of unknown function (DUF1843) Sulfotransfer_2 PF03567.14 CDJ86502.1 - 1.6 8.5 6.6 0.24 11.3 1.8 2.0 2 0 0 2 2 2 0 Sulfotransferase family DUF5564 PF17719.1 CDJ86502.1 - 3.3 7.9 0.0 3.3 7.9 0.0 3.4 4 0 0 4 4 4 0 Family of unknown function (DUF5564) Mod_r PF07200.13 CDJ86502.1 - 6 7.0 62.3 2 8.5 9.7 6.4 2 2 2 6 6 6 0 Modifier of rudimentary (Mod(r)) protein Gag_p17 PF00540.18 CDJ86502.1 - 7 6.6 12.2 0.25 11.3 2.2 3.3 3 2 0 3 3 3 0 gag gene protein p17 (matrix protein) Baculo_p24 PF05073.12 CDJ86503.1 - 0.44 10.3 6.9 0.14 11.9 1.4 2.1 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Muted PF14942.6 CDJ86503.1 - 0.77 10.1 10.6 3.2 8.1 6.2 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein C2 PF00168.30 CDJ86504.1 - 9.4e-47 157.6 0.0 5.2e-23 81.3 0.0 2.6 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.16 CDJ86504.1 - 3.3e-35 120.9 7.0 5.9e-35 120.1 7.0 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger zf-piccolo PF05715.13 CDJ86504.1 - 0.0089 16.2 5.7 0.019 15.1 5.7 1.6 1 0 0 1 1 1 1 Piccolo Zn-finger PI3K_C2 PF00792.24 CDJ86504.1 - 0.058 13.3 0.0 0.64 9.9 0.0 2.2 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 FYVE PF01363.21 CDJ86504.1 - 5 7.3 6.9 11 6.2 6.9 1.5 1 0 0 1 1 1 0 FYVE zinc finger GN3L_Grn1 PF08701.11 CDJ86508.1 - 0.041 14.0 0.1 0.052 13.7 0.1 1.2 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase YcbB PF08664.10 CDJ86508.1 - 0.064 13.3 0.1 0.074 13.1 0.1 1.1 1 0 0 1 1 1 0 YcbB domain RT_RNaseH_2 PF17919.1 CDJ86511.1 - 1.8e-58 194.7 0.0 1.6e-36 124.4 0.0 3.2 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ86511.1 - 7.9e-43 145.0 0.1 9e-33 112.7 0.0 3.4 4 0 0 4 4 4 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ86511.1 - 6.3e-35 120.7 0.0 4.7e-21 75.3 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDJ86511.1 - 1.8e-22 79.8 0.0 5.8e-22 78.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ86511.1 - 2.4e-16 59.6 0.1 5.6e-16 58.4 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CDJ86511.1 - 3.6e-05 23.4 0.0 0.00013 21.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain DNA_pol_viral_C PF00336.18 CDJ86511.1 - 6.8e-05 22.4 0.0 0.42 10.0 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase (viral) C-terminal domain zf-H2C2 PF09337.10 CDJ86511.1 - 0.012 15.8 0.1 0.037 14.2 0.1 2.0 1 0 0 1 1 1 0 H2C2 zinc finger Laminin_G_2 PF02210.24 CDJ86512.1 - 1.5e-30 106.4 0.0 5.7e-20 72.2 0.0 2.4 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 CDJ86512.1 - 3.8e-19 69.2 0.0 7.2e-11 42.4 0.0 2.6 2 0 0 2 2 2 2 Laminin G domain EGF PF00008.27 CDJ86512.1 - 3.3e-07 30.5 8.8 3.3e-07 30.5 8.8 8.8 10 0 0 10 10 10 4 EGF-like domain hEGF PF12661.7 CDJ86512.1 - 6e-06 26.7 4.9 6e-06 26.7 4.9 11.8 12 0 0 12 12 12 1 Human growth factor-like EGF GAIN PF16489.5 CDJ86512.1 - 0.0014 18.1 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Laminin_G_3 PF13385.6 CDJ86512.1 - 0.0039 17.3 0.0 0.14 12.3 0.0 2.4 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily 7tm_2 PF00002.24 CDJ86512.1 - 0.026 13.8 21.7 0.046 13.0 21.7 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) DUF1080 PF06439.11 CDJ86512.1 - 0.062 13.4 0.0 2 8.5 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1080) VWA PF00092.28 CDJ86513.1 - 2.7e-32 112.4 0.1 6.4e-31 107.9 0.0 2.6 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 CDJ86513.1 - 4.9e-14 52.9 0.0 2.5e-12 47.4 0.0 2.6 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 CDJ86513.1 - 1.7e-06 27.6 0.5 3.5e-06 26.6 0.2 1.7 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein DUF1194 PF06707.11 CDJ86513.1 - 0.0076 15.5 0.1 0.015 14.5 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1194) VWA_3 PF13768.6 CDJ86513.1 - 0.024 14.6 0.0 0.18 11.8 0.0 2.3 2 0 0 2 2 2 0 von Willebrand factor type A domain Ras PF00071.22 CDJ86514.1 - 4.8e-68 227.9 0.5 5.5e-68 227.7 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ86514.1 - 1.8e-37 128.2 0.4 3.9e-37 127.1 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ86514.1 - 1.5e-17 63.6 0.1 1.8e-17 63.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CDJ86514.1 - 4.6e-07 29.9 0.3 0.0081 16.1 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CDJ86514.1 - 7.5e-06 25.6 0.2 1.9e-05 24.3 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CDJ86514.1 - 8.7e-06 25.3 0.0 1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDJ86514.1 - 2.1e-05 24.6 0.0 3.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CDJ86514.1 - 3.5e-05 23.3 0.0 4.4e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 CDJ86514.1 - 0.0062 16.1 0.0 0.048 13.2 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.29 CDJ86514.1 - 0.0069 16.8 0.0 0.3 11.5 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 CDJ86514.1 - 0.018 14.8 0.1 0.45 10.3 0.1 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 CDJ86514.1 - 0.021 15.2 0.0 0.036 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 CDJ86514.1 - 0.03 13.8 0.0 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 CDJ86514.1 - 0.035 14.4 0.0 0.085 13.1 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.6 CDJ86514.1 - 0.062 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 CDJ86514.1 - 0.068 13.2 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Septin PF00735.18 CDJ86514.1 - 0.07 12.4 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Septin ABC_tran PF00005.27 CDJ86514.1 - 0.073 13.6 0.0 0.13 12.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 CDJ86514.1 - 0.097 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein BTB PF00651.31 CDJ86515.1 - 1.5e-10 41.3 0.0 0.0016 18.7 0.0 3.2 2 1 0 2 2 2 2 BTB/POZ domain BACK PF07707.15 CDJ86515.1 - 7.2e-07 29.3 2.6 1.3e-06 28.5 0.4 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch DUF1679 PF07914.11 CDJ86518.1 - 8.3e-33 113.9 0.3 1.1e-32 113.5 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 CDJ86518.1 - 2.7e-16 59.7 0.7 4.3e-16 59.1 0.7 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 CDJ86518.1 - 3.3e-11 43.6 0.1 5.8e-11 42.8 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 CDJ86518.1 - 0.019 14.2 0.1 0.082 12.1 0.0 2.0 3 0 0 3 3 3 0 Fructosamine kinase Pkinase_Tyr PF07714.17 CDJ86518.1 - 0.027 13.7 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Choline_kinase PF01633.20 CDJ86518.1 - 0.03 13.9 0.2 0.078 12.6 0.2 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 CDJ86518.1 - 0.04 13.3 0.0 2.5 7.4 0.0 2.3 1 1 0 2 2 2 0 Protein kinase domain ComR_TPR PF18710.1 CDJ86518.1 - 0.11 12.0 1.5 1.1 8.8 0.0 2.4 3 0 0 3 3 3 0 ComR tetratricopeptide DUF1679 PF07914.11 CDJ86519.1 - 1.1e-33 116.8 0.0 1.3e-33 116.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 CDJ86519.1 - 6.6e-16 58.5 0.2 1.8e-14 53.7 0.2 2.3 2 1 0 2 2 2 1 Ecdysteroid kinase APH PF01636.23 CDJ86519.1 - 5.1e-09 36.4 0.0 8.1e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CDJ86519.1 - 0.04 13.5 0.0 0.097 12.3 0.0 1.6 1 0 0 1 1 1 0 RIO1 family SID-1_RNA_chan PF13965.6 CDJ86520.1 - 1.4e-93 314.4 12.6 2e-93 313.9 12.6 1.2 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 PhnJ PF06007.11 CDJ86520.1 - 0.043 12.8 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ Ninjurin PF04923.12 CDJ86520.1 - 6.9 6.7 7.2 2.9 7.9 0.5 3.1 2 1 1 3 3 3 0 Ninjurin DDE_Tnp_1_6 PF13751.6 CDJ86521.1 - 0.019 15.2 2.5 0.03 14.5 2.5 1.5 1 0 0 1 1 1 0 Transposase DDE domain DUF1152 PF06626.12 CDJ86521.1 - 0.074 12.3 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1152) TFIIA PF03153.13 CDJ86522.1 - 1.4e-59 203.2 23.6 1.6e-57 196.4 23.6 2.0 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit MotY_N PF18393.1 CDJ86522.1 - 0.023 14.8 0.5 0.054 13.6 0.5 1.6 1 0 0 1 1 1 0 MotY N-terminal domain zf-C2H2 PF00096.26 CDJ86523.1 - 1.1e-07 31.9 17.5 2.1e-05 24.7 4.1 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ86523.1 - 0.0002 21.9 16.4 0.0086 16.8 3.0 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger PhnA_Zn_Ribbon PF08274.12 CDJ86523.1 - 0.0015 18.5 1.1 0.057 13.4 0.2 2.9 2 1 1 3 3 3 2 PhnA Zinc-Ribbon Rhodanese_C PF12368.8 CDJ86523.1 - 0.011 16.1 4.6 0.025 14.9 1.0 2.2 2 0 0 2 2 2 0 Rhodanase C-terminal Siva PF05458.12 CDJ86523.1 - 0.02 14.6 0.8 0.036 13.8 0.8 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-BED PF02892.15 CDJ86523.1 - 0.023 14.7 8.4 0.033 14.2 2.2 2.5 2 0 0 2 2 2 0 BED zinc finger zinc_ribbon_15 PF17032.5 CDJ86523.1 - 0.047 14.4 7.1 0.35 11.6 1.6 2.5 1 1 3 4 4 4 0 zinc-ribbon family zf-C2H2_jaz PF12171.8 CDJ86523.1 - 0.073 13.4 13.4 0.68 10.3 2.5 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-MYST PF17772.1 CDJ86523.1 - 0.074 12.7 8.7 0.24 11.0 1.4 2.9 2 1 1 3 3 3 0 MYST family zinc finger domain DUF2719 PF10891.8 CDJ86523.1 - 0.18 11.7 2.5 0.37 10.7 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2719) ADK_lid PF05191.14 CDJ86523.1 - 0.19 11.7 8.9 0.25 11.4 2.4 3.0 2 1 0 2 2 2 0 Adenylate kinase, active site lid FYVE_2 PF02318.16 CDJ86523.1 - 0.2 11.9 2.7 0.38 11.0 2.7 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Gin PF10764.9 CDJ86523.1 - 0.21 11.6 1.2 1.8 8.6 0.0 2.7 3 0 0 3 3 3 0 Inhibitor of sigma-G Gin zinc_ribbon_10 PF10058.9 CDJ86523.1 - 0.35 10.6 5.8 1.7 8.4 4.0 2.5 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-Di19 PF05605.12 CDJ86523.1 - 0.57 10.5 13.1 0.11 12.8 8.7 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 CDJ86523.1 - 1.2 9.7 15.6 5.5 7.6 1.1 3.8 3 1 0 3 3 3 0 Zinc-finger double domain LIM PF00412.22 CDJ86523.1 - 2.6 8.3 12.1 3.1 8.1 2.5 2.7 1 1 1 2 2 2 0 LIM domain Zn_Tnp_IS1595 PF12760.7 CDJ86523.1 - 3.9 7.5 8.9 6.5 6.8 2.9 2.7 1 1 2 3 3 2 0 Transposase zinc-ribbon domain zf-met PF12874.7 CDJ86523.1 - 8.3 7.0 10.9 16 6.1 1.3 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 CDJ86523.1 - 8.8 6.5 9.9 18 5.6 2.6 2.8 1 1 2 3 3 3 0 Zinc ribbon domain DUF4998 PF16389.5 CDJ86524.1 - 0.044 13.4 0.1 0.066 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function TRP PF06011.12 CDJ86524.1 - 0.083 11.6 0.0 0.093 11.4 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Pkinase_Tyr PF07714.17 CDJ86525.1 - 1.8e-55 188.0 0.0 4.8e-55 186.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ86525.1 - 1.6e-47 162.1 0.0 3.4e-47 161.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain SH3_9 PF14604.6 CDJ86525.1 - 8.1e-14 51.2 0.1 1.5e-13 50.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDJ86525.1 - 1.3e-08 34.3 0.0 2.4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDJ86525.1 - 3.6e-08 33.0 0.0 7.4e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain NOB1_Zn_bind PF08772.11 CDJ86525.1 - 0.037 14.2 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like YcbB PF08664.10 CDJ86525.1 - 0.29 11.2 1.6 0.76 9.8 1.0 1.9 1 1 0 1 1 1 0 YcbB domain zf-AN1 PF01428.16 CDJ86526.1 - 9.2e-17 60.9 35.4 1.7e-09 37.7 13.0 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger ATG7_N PF16420.5 CDJ86526.1 - 0.13 11.9 0.1 1.3 8.6 0.0 1.9 1 1 1 2 2 2 0 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus Transp_Tc5_C PF04236.15 CDJ86526.1 - 0.44 11.0 23.4 2.5 8.5 7.0 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Ubiq_cyt_C_chap PF03981.12 CDJ86527.1 - 3.3e-27 95.3 0.9 5.3e-27 94.6 0.9 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Soc PF16855.5 CDJ86527.1 - 0.077 13.5 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 Small outer capsid protein 7tm_2 PF00002.24 CDJ86528.1 - 3.9e-37 127.9 11.7 5.2e-37 127.4 11.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 CDJ86528.1 - 9.7e-08 32.2 6.6 9.7e-08 32.2 6.6 2.0 2 0 0 2 2 2 1 Hormone receptor domain 7tm_3 PF00003.22 CDJ86528.1 - 0.0022 17.8 16.4 0.0066 16.2 16.0 1.9 1 1 1 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR CNP_C_terminal PF17839.1 CDJ86529.1 - 0.039 14.7 3.6 2.5 8.9 0.0 3.3 3 0 0 3 3 3 0 C-terminal domain of cyclic nucleotide phosphodiesterase WD40_alt PF14077.6 CDJ86529.1 - 2 8.3 5.6 2.3 8.2 0.1 4.0 4 0 0 4 4 4 0 Alternative WD40 repeat motif BRCT PF00533.26 CDJ86530.1 - 2.2e-25 88.9 0.0 6.1e-09 36.1 0.0 4.4 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CDJ86530.1 - 4.7e-22 77.7 0.3 1.9e-14 53.3 0.0 4.0 4 0 0 4 4 4 3 twin BRCT domain BRCT_2 PF16589.5 CDJ86530.1 - 1.8e-12 47.5 0.0 0.0004 20.7 0.0 4.2 4 0 0 4 4 4 2 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 CDJ86530.1 - 1.3e-10 41.0 0.0 1e-07 31.8 0.0 2.4 2 0 0 2 2 2 2 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 CDJ86530.1 - 0.0041 17.4 2.0 0.91 9.9 0.0 3.9 4 1 0 4 4 4 1 DNA ligase 3 BRCT domain zf-C2H2_4 PF13894.6 CDJ86532.1 - 2e-09 37.5 72.8 0.0037 18.0 1.1 13.2 13 0 0 13 13 13 6 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CDJ86532.1 - 0.00046 20.9 24.5 0.17 12.5 0.1 7.0 7 1 0 7 7 7 4 Zinc finger C2H2-type, 3 repeats zf-C2H2 PF00096.26 CDJ86532.1 - 0.0016 18.8 8.5 0.0057 17.0 1.5 11.7 13 0 0 13 13 13 5 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 CDJ86532.1 - 0.0052 16.5 0.6 0.0052 16.5 0.6 6.5 8 1 0 8 8 8 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 CDJ86532.1 - 0.29 11.5 0.0 0.29 11.5 0.0 6.2 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.15 CDJ86532.1 - 0.33 10.9 21.3 21 5.1 0.3 8.4 9 0 0 9 9 9 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain AKAP95 PF04988.12 CDJ86532.1 - 1.1 9.5 8.7 1.2 9.3 0.5 3.3 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_aberr PF17017.5 CDJ86532.1 - 6.8 6.8 18.7 4.4 7.4 1.1 4.6 5 0 0 5 5 5 0 Aberrant zinc-finger GILT PF03227.16 CDJ86533.1 - 3.4e-25 88.3 1.3 4.2e-25 88.0 0.7 1.4 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Thioredoxin_4 PF13462.6 CDJ86533.1 - 0.0088 16.2 0.0 4.5 7.4 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin Glutaredoxin PF00462.24 CDJ86533.1 - 0.027 14.7 0.2 0.21 11.8 0.1 2.2 2 0 0 2 2 2 0 Glutaredoxin Thioredoxin_2 PF13098.6 CDJ86533.1 - 0.11 12.9 0.6 0.24 11.9 0.1 1.7 1 1 1 2 2 2 0 Thioredoxin-like domain CAP PF00188.26 CDJ86535.1 - 2e-12 48.1 0.9 2e-12 48.1 0.9 1.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family CIAPIN1 PF05093.13 CDJ86535.1 - 1.4 9.5 5.5 0.24 11.9 1.0 1.9 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis CAP PF00188.26 CDJ86536.1 - 1.3e-14 55.1 4.0 1.7e-14 54.7 4.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ86536.1 - 0.0026 18.0 0.4 0.0026 18.0 0.4 2.1 2 1 0 2 2 2 1 Ancylostoma-associated secreted protein related Lectin_C PF00059.21 CDJ86537.1 - 1.2e-20 74.2 1.4 1.5e-20 73.9 1.4 1.1 1 0 0 1 1 1 1 Lectin C-type domain RVT_1 PF00078.27 CDJ86538.1 - 9.6e-25 87.4 0.1 1.3e-24 87.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lectin_C PF00059.21 CDJ86539.1 - 1.7e-17 64.1 0.1 2.1e-17 63.8 0.1 1.1 1 0 0 1 1 1 1 Lectin C-type domain Methyltransf_4 PF02390.17 CDJ86540.1 - 1.2e-56 190.9 0.0 2.1e-56 190.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Mito_carr PF00153.27 CDJ86540.1 - 2.1e-50 168.6 0.3 1.4e-17 63.4 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_25 PF13649.6 CDJ86540.1 - 0.0061 17.2 0.0 0.012 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ86540.1 - 0.038 14.7 0.0 0.15 12.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Lar_restr_allev PF14354.6 CDJ86540.1 - 0.052 13.9 0.8 0.052 13.9 0.8 2.0 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-RRN7 PF11781.8 CDJ86540.1 - 0.055 13.2 0.1 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 AAR2 PF05282.11 CDJ86540.1 - 0.073 12.5 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 AAR2 protein MCR_gamma PF02240.16 CDJ86540.1 - 0.099 11.9 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyl-coenzyme M reductase gamma subunit Methyltransf_31 PF13847.6 CDJ86540.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain zf-nanos PF05741.13 CDJ86541.1 - 6.7e-19 67.9 2.2 1.2e-18 67.0 2.2 1.5 1 0 0 1 1 1 1 Nanos RNA binding domain HypA PF01155.19 CDJ86541.1 - 0.056 13.5 4.5 2.3 8.2 0.8 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-CCHC_6 PF15288.6 CDJ86541.1 - 0.13 12.2 0.6 0.78 9.6 0.6 2.5 1 0 0 1 1 1 0 Zinc knuckle SAGA-Tad1 PF12767.7 CDJ86541.1 - 0.2 11.4 4.5 0.38 10.5 4.5 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF4083 PF13314.6 CDJ86543.1 - 0.23 11.4 2.8 0.53 10.3 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) Sec15 PF04091.12 CDJ86544.1 - 5.1e-79 266.0 1.1 5.1e-79 266.0 1.1 1.8 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Vps51 PF08700.11 CDJ86544.1 - 0.00011 22.1 0.5 0.00078 19.5 0.0 2.7 2 1 0 2 2 2 1 Vps51/Vps67 Sec8_exocyst PF04048.14 CDJ86544.1 - 0.19 11.6 5.5 0.16 11.9 0.8 2.8 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain Herpes_UL36 PF03586.13 CDJ86544.1 - 0.28 10.5 2.5 0.54 9.5 0.2 2.3 2 0 0 2 2 2 0 Herpesvirus UL36 tegument protein COG2 PF06148.11 CDJ86544.1 - 0.59 10.2 6.1 0.72 9.9 2.4 3.0 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF229 PF02995.17 CDJ86545.1 - 6.1e-38 130.7 1.2 5.8e-31 107.7 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF229) DUF229 PF02995.17 CDJ86546.1 - 5e-79 266.2 2.2 6.4e-79 265.8 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Leader_CPA1 PF08252.11 CDJ86546.1 - 0.029 13.8 0.9 1.1 8.8 0.1 2.7 2 0 0 2 2 2 0 arg-2/CPA1 leader peptide cNMP_binding PF00027.29 CDJ86549.1 - 2.5e-37 126.8 0.1 4.5e-11 42.7 0.0 3.3 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Beta-lactamase PF00144.24 CDJ86550.1 - 1.1e-36 126.8 0.0 1.4e-36 126.4 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Lectin_leg-like PF03388.13 CDJ86551.1 - 0.21 10.9 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Legume-like lectin family Beta-lactamase PF00144.24 CDJ86551.1 - 0.21 10.8 0.0 0.23 10.6 0.0 1.0 1 0 0 1 1 1 0 Beta-lactamase SNF2_N PF00176.23 CDJ86552.1 - 5.1e-27 94.5 0.0 1e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ86552.1 - 5.2e-13 49.3 0.0 1.4e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HARP PF07443.13 CDJ86552.1 - 5.6e-09 35.5 0.0 1.3e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 HepA-related protein (HARP) ResIII PF04851.15 CDJ86552.1 - 0.00014 21.9 0.0 0.00059 19.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 CDJ86552.1 - 0.016 15.2 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain ERCC3_RAD25_C PF16203.5 CDJ86552.1 - 0.018 14.3 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Glycohydro_20b2 PF14845.6 CDJ86552.1 - 0.042 14.5 0.2 1.4 9.6 0.2 2.5 2 0 0 2 2 2 0 beta-acetyl hexosaminidase like PglZ PF08665.12 CDJ86552.1 - 0.13 12.3 0.1 0.43 10.7 0.0 1.8 2 0 0 2 2 2 0 PglZ domain Casc1_N PF15927.5 CDJ86552.1 - 1 9.0 6.2 2.3 7.9 5.4 1.9 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus EF-hand_8 PF13833.6 CDJ86554.1 - 1.2e-09 37.8 0.0 0.00013 21.7 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 CDJ86554.1 - 3.4e-09 37.0 0.0 0.0031 17.9 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CDJ86554.1 - 3.6e-08 32.4 1.0 0.0022 17.4 0.0 3.7 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 CDJ86554.1 - 4.9e-06 26.1 0.1 0.056 13.4 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDJ86554.1 - 0.0051 16.2 0.0 1.4 8.6 0.0 3.4 4 0 0 4 4 4 1 EF hand Retrotrans_gag PF03732.17 CDJ86555.1 - 2.3e-05 24.6 0.0 5.2e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Retrotransposon gag protein PNMA PF14893.6 CDJ86555.1 - 0.0012 18.4 0.7 0.03 13.7 0.2 2.1 1 1 0 2 2 2 1 PNMA SCAN PF02023.17 CDJ86555.1 - 0.018 14.8 1.6 0.086 12.7 0.1 2.6 3 0 0 3 3 3 0 SCAN domain Adaptin_binding PF10199.9 CDJ86555.1 - 0.093 13.3 0.0 0.29 11.7 0.0 1.8 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 RT_RNaseH_2 PF17919.1 CDJ86556.1 - 2.7e-27 94.7 0.0 5.3e-27 93.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ86556.1 - 6.2e-27 93.9 0.1 1.2e-26 93.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ86556.1 - 5.3e-16 58.8 0.0 1.2e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CDJ86556.1 - 0.00037 21.0 0.0 0.001 19.6 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ86556.1 - 0.0024 18.2 0.0 0.0064 16.8 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ86556.1 - 0.0087 16.7 0.1 0.017 15.7 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 CDJ86556.1 - 0.1 12.4 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Peptidase_A17 PF05380.13 CDJ86556.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Pao retrotransposon peptidase AAA_30 PF13604.6 CDJ86557.1 - 0.078 12.7 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain ECH_1 PF00378.20 CDJ86558.1 - 4.7e-34 117.8 0.0 5.5e-28 97.9 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CDJ86558.1 - 4.6e-13 49.4 0.0 4.5e-09 36.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 CDJ86558.1 - 0.029 14.3 0.0 2.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 DUF4139 PF13598.6 CDJ86559.1 - 5.4e-49 166.7 0.1 6.2e-49 166.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) Top6b_C PF18000.1 CDJ86559.1 - 0.0058 16.8 0.2 0.014 15.6 0.2 1.6 1 0 0 1 1 1 1 Type 2 DNA topoisomerase 6 subunit B C-terminal domain Collagen PF01391.18 CDJ86560.1 - 1.8e-27 94.9 102.1 4.8e-11 42.2 35.1 3.7 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ86560.1 - 0.12 12.5 0.1 0.16 12.1 0.1 1.1 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain DUF4140 PF13600.6 CDJ86561.1 - 3.4e-22 78.7 5.8 9.6e-20 70.9 5.3 2.1 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) CENP-F_leu_zip PF10473.9 CDJ86561.1 - 0.009 16.0 2.3 1 9.4 0.1 2.2 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.19 CDJ86561.1 - 0.0098 13.8 0.9 0.7 7.6 0.2 2.0 2 0 0 2 2 2 2 Myosin tail EMP24_GP25L PF01105.24 CDJ86561.1 - 0.012 15.6 0.7 0.053 13.5 0.2 1.9 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD FlaC_arch PF05377.11 CDJ86561.1 - 0.016 15.6 3.4 0.87 10.0 0.0 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4618 PF15397.6 CDJ86561.1 - 0.025 14.0 1.1 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF4201 PF13870.6 CDJ86561.1 - 0.03 14.0 2.8 0.66 9.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF4795 PF16043.5 CDJ86561.1 - 0.059 13.0 0.7 9.7 5.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) BRE1 PF08647.11 CDJ86561.1 - 0.069 13.2 1.7 1.9 8.6 0.2 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase TolA_bind_tri PF16331.5 CDJ86561.1 - 0.088 12.9 2.1 2.7 8.1 0.1 2.6 3 0 0 3 3 3 0 TolA binding protein trimerisation DUF1664 PF07889.12 CDJ86561.1 - 0.1 12.6 2.8 3.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 CDJ86561.1 - 0.13 12.8 4.2 1 9.9 0.4 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region ABC_tran_CTD PF16326.5 CDJ86561.1 - 0.16 12.3 3.5 0.32 11.3 0.4 2.6 2 2 0 2 2 2 0 ABC transporter C-terminal domain Nsp1_C PF05064.13 CDJ86561.1 - 0.2 11.5 2.5 4.2 7.2 0.4 2.4 2 0 0 2 2 2 0 Nsp1-like C-terminal region Importin_rep_6 PF18829.1 CDJ86561.1 - 0.21 11.8 1.4 0.37 10.9 0.1 2.0 3 0 0 3 3 2 0 Importin repeat 6 BLOC1_2 PF10046.9 CDJ86561.1 - 0.21 11.9 2.1 2 8.8 0.1 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TRAF_BIRC3_bd PF16673.5 CDJ86561.1 - 0.58 10.0 5.1 0.64 9.9 0.3 2.6 2 1 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Cnn_1N PF07989.11 CDJ86561.1 - 4 7.7 6.5 6.9 6.9 0.1 2.6 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 Proteasome PF00227.26 CDJ86562.1 - 1.9e-58 197.1 0.4 2.3e-58 196.8 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ86562.1 - 7e-14 51.2 0.0 1.3e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Beta-lactamase PF00144.24 CDJ86563.1 - 3.1e-33 115.4 0.0 4.4e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase ICAP-1_inte_bdg PF10480.9 CDJ86563.1 - 1.1e-11 45.2 0.0 1.8e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Beta-1 integrin binding protein PID PF00640.23 CDJ86563.1 - 2.5e-05 24.3 0.1 6.6e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) Peptidase_S11 PF00768.20 CDJ86563.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase NifU_N PF01592.16 CDJ86564.1 - 9.5e-59 197.1 0.3 1.2e-58 196.9 0.3 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain DUF3659 PF12396.8 CDJ86564.1 - 0.032 14.2 1.0 0.18 11.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) Beta-lactamase PF00144.24 CDJ86565.1 - 5.1e-24 85.1 0.0 6.6e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase sCache_like PF16736.5 CDJ86565.1 - 0.13 12.4 0.1 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 Single Cache-like SAS-6_N PF16531.5 CDJ86566.1 - 5e-10 39.8 0.0 2.1e-09 37.8 0.0 2.1 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal FliJ PF02050.16 CDJ86566.1 - 2.4e-05 24.6 26.2 0.028 14.7 0.4 4.3 3 1 1 4 4 4 2 Flagellar FliJ protein GAS PF13851.6 CDJ86566.1 - 4.1e-05 23.0 47.2 0.0034 16.7 6.4 4.2 3 1 1 4 4 4 3 Growth-arrest specific micro-tubule binding DUF4795 PF16043.5 CDJ86566.1 - 6e-05 22.7 39.6 0.00012 21.8 16.2 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF4795) Fib_alpha PF08702.10 CDJ86566.1 - 0.00019 21.6 30.3 0.0045 17.2 11.5 3.4 3 0 0 3 3 3 2 Fibrinogen alpha/beta chain family ZapB PF06005.12 CDJ86566.1 - 0.00087 19.7 40.9 0.051 14.0 4.1 4.7 3 1 1 4 4 4 2 Cell division protein ZapB DUF1664 PF07889.12 CDJ86566.1 - 0.0016 18.4 29.0 0.21 11.6 2.8 4.2 3 1 1 4 4 4 3 Protein of unknown function (DUF1664) APG6_N PF17675.1 CDJ86566.1 - 0.0082 16.7 60.3 0.012 16.2 8.5 4.3 3 1 1 4 4 4 2 Apg6 coiled-coil region SlyX PF04102.12 CDJ86566.1 - 0.0093 16.6 35.3 0.076 13.6 3.2 5.6 4 1 1 6 6 5 3 SlyX PspA_IM30 PF04012.12 CDJ86566.1 - 0.0095 15.5 33.8 0.036 13.7 1.5 3.7 2 2 1 3 3 3 2 PspA/IM30 family CENP-F_leu_zip PF10473.9 CDJ86566.1 - 0.012 15.7 60.0 0.37 10.8 8.2 4.8 2 2 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 CDJ86566.1 - 0.017 15.2 25.2 0.81 9.7 1.9 4.8 3 2 2 5 5 5 0 Laminin Domain II DUF4446 PF14584.6 CDJ86566.1 - 0.019 14.9 21.9 0.68 9.9 0.3 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF4446) YabA PF06156.13 CDJ86566.1 - 0.032 14.9 27.4 4.4 8.0 1.9 4.5 4 0 0 4 4 4 0 Initiation control protein YabA Prefoldin_2 PF01920.20 CDJ86566.1 - 0.038 13.9 47.1 0.05 13.6 4.2 5.9 4 2 2 6 6 6 0 Prefoldin subunit TMF_DNA_bd PF12329.8 CDJ86566.1 - 0.043 13.8 51.8 0.035 14.1 5.5 5.4 3 2 3 6 6 6 0 TATA element modulatory factor 1 DNA binding Filament PF00038.21 CDJ86566.1 - 0.067 12.8 47.0 0.065 12.8 9.9 4.0 2 2 1 4 4 4 0 Intermediate filament protein Clr5 PF14420.6 CDJ86566.1 - 0.094 13.0 0.7 0.75 10.1 0.4 2.6 2 0 0 2 2 2 0 Clr5 domain MAD PF05557.13 CDJ86566.1 - 0.098 11.0 42.8 0.47 8.7 17.0 2.1 2 0 0 2 2 2 0 Mitotic checkpoint protein Spc7 PF08317.11 CDJ86566.1 - 0.11 11.3 52.4 0.099 11.5 8.7 3.6 2 2 1 3 3 3 0 Spc7 kinetochore protein RasGAP_C PF03836.15 CDJ86566.1 - 0.12 12.6 24.8 0.42 10.8 1.0 4.2 3 1 1 4 4 4 0 RasGAP C-terminus DUF3450 PF11932.8 CDJ86566.1 - 0.16 11.3 36.3 1 8.6 6.8 4.1 2 2 1 4 4 4 0 Protein of unknown function (DUF3450) DUF948 PF06103.11 CDJ86566.1 - 0.16 12.3 10.4 11 6.4 0.6 4.6 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF724 PF05266.14 CDJ86566.1 - 0.28 11.0 43.2 0.29 11.0 4.7 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF724) KxDL PF10241.9 CDJ86566.1 - 0.29 11.5 19.9 3 8.2 0.1 5.4 2 2 3 6 6 6 0 Uncharacterized conserved protein FPP PF05911.11 CDJ86566.1 - 0.34 9.0 44.0 0.26 9.4 20.8 2.6 2 1 0 2 2 2 0 Filament-like plant protein, long coiled-coil TPR_MLP1_2 PF07926.12 CDJ86566.1 - 0.35 10.9 44.1 10 6.2 19.0 4.5 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein Sec34 PF04136.15 CDJ86566.1 - 0.47 10.3 26.8 0.52 10.2 2.6 4.4 4 1 0 4 4 4 0 Sec34-like family MscS_porin PF12795.7 CDJ86566.1 - 0.49 9.9 29.0 1.9 8.0 0.8 4.0 3 1 1 4 4 4 0 Mechanosensitive ion channel porin domain Herpes_UL6 PF01763.16 CDJ86566.1 - 0.51 8.8 24.1 0.33 9.4 1.7 3.8 2 2 2 4 4 4 0 Herpesvirus UL6 like Yuri_gagarin PF15934.5 CDJ86566.1 - 0.98 9.2 33.7 0.11 12.4 10.5 3.5 2 1 1 3 3 3 0 Yuri gagarin ADIP PF11559.8 CDJ86566.1 - 1.1 9.3 45.8 0.057 13.5 7.0 4.2 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding NABP PF07990.12 CDJ86566.1 - 1.2 8.6 4.1 0.77 9.2 0.3 2.0 2 0 0 2 2 2 0 Nucleic acid binding protein NABP ATG16 PF08614.11 CDJ86566.1 - 1.4 9.1 52.7 0.084 13.1 6.9 3.5 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) Syntaxin-6_N PF09177.11 CDJ86566.1 - 1.4 9.5 31.3 8.5 7.0 3.0 4.6 3 2 1 4 4 4 0 Syntaxin 6, N-terminal KASH_CCD PF14662.6 CDJ86566.1 - 1.6 8.6 48.1 0.036 13.9 16.5 3.2 2 1 1 3 3 2 0 Coiled-coil region of CCDC155 or KASH Sas10_Utp3 PF04000.15 CDJ86566.1 - 1.7 9.3 11.7 19 6.0 0.2 4.6 4 1 0 4 4 4 0 Sas10/Utp3/C1D family HOOK PF05622.12 CDJ86566.1 - 2.3 6.3 44.6 0.12 10.5 17.7 2.5 2 1 0 2 2 2 0 HOOK protein DUF4201 PF13870.6 CDJ86566.1 - 2.4 7.9 48.6 0.56 9.9 8.9 4.6 2 2 1 4 4 4 0 Domain of unknown function (DUF4201) DivIC PF04977.15 CDJ86566.1 - 2.8 7.8 34.7 3.4 7.5 1.5 5.4 4 1 1 5 5 5 0 Septum formation initiator Nsp1_C PF05064.13 CDJ86566.1 - 3 7.7 26.1 0.089 12.6 1.1 4.6 3 1 0 4 4 4 0 Nsp1-like C-terminal region Baculo_PEP_C PF04513.12 CDJ86566.1 - 3.2 7.8 6.0 50 3.9 0.4 3.7 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dad4 PF08650.10 CDJ86566.1 - 3.5 7.7 13.8 0.16 12.0 0.9 4.2 4 2 1 5 5 3 0 DASH complex subunit Dad4 DHR10 PF18595.1 CDJ86566.1 - 3.9 7.6 55.7 0.82 9.7 9.2 4.5 3 2 1 4 4 4 0 Designed helical repeat protein 10 domain DUF3584 PF12128.8 CDJ86566.1 - 4 4.8 38.4 2.3 5.7 14.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) BLOC1_2 PF10046.9 CDJ86566.1 - 4.3 7.7 32.9 3.6 8.0 2.1 4.6 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 CDJ86566.1 - 4.7 7.7 16.1 20 5.7 0.2 4.8 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.6 CDJ86566.1 - 6 5.4 35.8 4.3 5.8 13.6 3.3 2 2 0 2 2 2 0 AAA domain Snapin_Pallidin PF14712.6 CDJ86566.1 - 6.1 7.3 28.2 16 6.0 3.5 4.7 4 1 1 5 5 5 0 Snapin/Pallidin ERM PF00769.19 CDJ86566.1 - 6.2 6.6 54.8 0.022 14.6 4.2 4.0 2 2 1 4 4 4 0 Ezrin/radixin/moesin family TolA_bind_tri PF16331.5 CDJ86566.1 - 8.2 6.6 28.5 2.1 8.5 2.7 5.1 3 2 2 5 5 5 0 TolA binding protein trimerisation NAD_synthase PF02540.17 CDJ86567.1 - 6.1e-27 94.3 0.0 2.1e-26 92.5 0.0 1.7 1 1 0 1 1 1 1 NAD synthase TRAM_LAG1_CLN8 PF03798.16 CDJ86568.1 - 5.7e-19 68.6 19.8 1.2e-18 67.6 19.8 1.5 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 CDJ86568.1 - 1.8e-15 56.3 0.0 6.2e-15 54.6 0.0 2.0 1 0 0 1 1 1 1 TRAM1-like protein DUF2895 PF11444.8 CDJ86569.1 - 0.082 12.3 0.0 0.083 12.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) RA PF00788.23 CDJ86570.1 - 4.5e-13 49.7 0.2 8.1e-13 48.8 0.2 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Nore1-SARAH PF16517.5 CDJ86570.1 - 5.2e-12 45.5 2.1 1e-11 44.5 2.1 1.5 1 0 0 1 1 1 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain MNR PF15718.5 CDJ86570.1 - 0.013 13.7 0.1 0.014 13.5 0.1 1.0 1 0 0 1 1 1 0 Protein moonraker IATP PF04568.12 CDJ86570.1 - 0.24 11.9 0.4 0.24 11.9 0.4 2.3 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP C1_1 PF00130.22 CDJ86572.1 - 2.9e-14 52.7 8.4 4.7e-14 52.0 8.4 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C6_DPF PF10170.9 CDJ86574.1 - 1.2e-20 73.6 3.8 1.9e-20 73.0 3.8 1.3 1 0 0 1 1 1 1 Cysteine-rich domain RVT_1 PF00078.27 CDJ86575.1 - 8.2e-19 68.0 0.0 1.3e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PAN_1 PF00024.26 CDJ86576.1 - 4.6e-14 52.1 8.1 2e-06 27.6 0.0 2.9 3 0 0 3 3 3 2 PAN domain CppA_N PF14506.6 CDJ86576.1 - 0.14 12.2 0.2 0.43 10.7 0.2 1.8 1 0 0 1 1 1 0 CppA N-terminal MANEC PF07502.14 CDJ86576.1 - 0.25 11.6 5.6 0.81 10.0 1.7 2.7 2 0 0 2 2 2 0 MANEC domain PAN_4 PF14295.6 CDJ86576.1 - 1.6 8.7 4.9 0.49 10.3 0.7 2.3 2 0 0 2 2 2 0 PAN domain Med22 PF06179.12 CDJ86577.1 - 2.6e-23 82.3 4.1 3.5e-23 81.8 4.1 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF4862 PF16154.5 CDJ86577.1 - 0.04 13.3 0.2 0.055 12.8 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4862) DUF601 PF04642.12 CDJ86577.1 - 0.1 12.1 1.6 0.13 11.7 1.6 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF601 COX6A PF02046.15 CDJ86578.1 - 3.3e-20 72.6 1.2 4.1e-20 72.3 1.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa STAG PF08514.11 CDJ86579.1 - 1.2e-28 99.3 4.8 2.3e-28 98.4 0.2 3.3 3 0 0 3 3 3 1 STAG domain YyzF PF14116.6 CDJ86579.1 - 0.019 15.0 0.1 0.21 11.6 0.0 2.6 2 0 0 2 2 2 0 YyzF-like protein COX6A PF02046.15 CDJ86580.1 - 3.2e-20 72.7 0.2 4e-20 72.4 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Carb_anhydrase PF00194.21 CDJ86582.1 - 4.8e-61 206.5 0.0 5.7e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF3750 PF12570.8 CDJ86582.1 - 0.046 14.4 1.3 4.1 8.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3750) Pkinase PF00069.25 CDJ86584.1 - 1e-17 64.4 0.0 1.3e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ86584.1 - 3.3e-12 46.2 0.0 3.8e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ86584.1 - 0.00014 21.9 0.0 0.15 12.0 0.0 2.2 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CDJ86584.1 - 0.0021 17.4 1.1 0.0037 16.6 0.2 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family D_CNTX PF17492.2 CDJ86586.1 - 0.063 13.5 1.4 0.17 12.1 1.4 1.7 1 0 0 1 1 1 0 Delta Ctenitoxins CAP PF00188.26 CDJ86586.1 - 0.1 13.5 3.9 0.12 13.2 0.3 2.3 2 1 0 2 2 2 0 Cysteine-rich secretory protein family RPE65 PF03055.15 CDJ86587.1 - 7.6e-35 121.0 0.3 1.5e-34 120.0 0.3 1.4 1 1 0 1 1 1 1 Retinal pigment epithelial membrane protein Forkhead PF00250.18 CDJ86588.1 - 3.5e-30 104.1 0.6 6.2e-30 103.3 0.3 1.6 2 0 0 2 2 2 1 Forkhead domain Linker_histone PF00538.19 CDJ86588.1 - 0.077 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 linker histone H1 and H5 family CRAL_TRIO PF00650.20 CDJ86589.1 - 1.5e-23 83.3 0.0 2.3e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CDJ86589.1 - 0.053 13.7 0.0 0.12 12.5 0.0 1.6 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain DUF4512 PF14975.6 CDJ86590.1 - 5.2e-05 24.0 12.2 0.00019 22.1 12.2 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4512) Globin PF00042.22 CDJ86591.1 - 0.0013 19.3 0.0 0.0019 18.8 0.0 1.3 1 0 0 1 1 1 1 Globin zf-MIZ PF02891.20 CDJ86592.1 - 6.4e-13 48.2 2.3 6.4e-13 48.2 2.3 1.8 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CDJ86592.1 - 0.24 11.3 3.2 0.2 11.5 0.5 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Aldo_ket_red PF00248.21 CDJ86594.1 - 8.9e-07 28.4 0.0 1.1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DUF61 PF01886.16 CDJ86595.1 - 0.082 12.9 0.1 2.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF61 BolA PF01722.18 CDJ86596.1 - 5.7e-05 23.3 0.0 9e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 BolA-like protein RICTOR_V PF14668.6 CDJ86596.1 - 0.033 14.4 0.1 0.092 13.0 0.1 1.7 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 DUF608 PF04685.13 CDJ86597.1 - 1.4e-153 511.4 3.0 1.4e-153 511.4 3.0 1.4 2 0 0 2 2 2 1 Glycosyl-hydrolase family 116, catalytic region Glyco_hydr_116N PF12215.8 CDJ86597.1 - 1.5e-56 192.2 0.1 3.8e-56 190.8 0.1 1.6 2 0 0 2 2 2 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Bac_rhamnosid6H PF17389.2 CDJ86597.1 - 0.0044 16.3 0.5 0.0076 15.5 0.5 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF5127 PF17168.4 CDJ86597.1 - 0.02 14.7 0.1 0.045 13.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5127) FrhB_FdhB_N PF04422.13 CDJ86597.1 - 0.077 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term TFIID-18kDa PF02269.16 CDJ86598.1 - 2.1e-05 24.5 1.0 7.4e-05 22.7 0.2 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Herpes_UL17 PF04559.12 CDJ86598.1 - 0.029 13.2 0.0 0.08 11.7 0.0 1.7 1 1 0 1 1 1 0 Herpesvirus UL17 protein Glyco_hydr_116N PF12215.8 CDJ86599.1 - 2.8e-21 76.3 0.0 3.6e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Methyltransf_21 PF05050.12 CDJ86600.1 - 1.2e-17 64.4 0.0 1.8e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain F-box PF00646.33 CDJ86601.1 - 2.2e-06 27.4 0.9 3.6e-06 26.7 0.9 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDJ86601.1 - 0.0009 19.1 0.5 0.0015 18.3 0.5 1.4 1 0 0 1 1 1 1 F-box-like PRANC PF09372.10 CDJ86601.1 - 0.061 13.6 0.0 0.091 13.1 0.0 1.3 1 0 0 1 1 1 0 PRANC domain Homeobox_KN PF05920.11 CDJ86603.1 - 8.1e-16 57.6 0.1 1.6e-15 56.7 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CDJ86603.1 - 2.2e-07 30.6 0.8 4.3e-07 29.7 0.8 1.5 1 0 0 1 1 1 1 Homeodomain PGA2 PF07543.12 CDJ86603.1 - 0.024 14.6 0.1 0.024 14.6 0.1 1.7 2 0 0 2 2 2 0 Protein trafficking PGA2 BTB PF00651.31 CDJ86605.1 - 1.4e-21 76.8 0.3 2.8e-21 75.8 0.1 1.6 2 0 0 2 2 2 1 BTB/POZ domain MATH PF00917.26 CDJ86605.1 - 7.6e-18 64.7 0.1 1.3e-17 64.0 0.1 1.3 1 0 0 1 1 1 1 MATH domain RVT_1 PF00078.27 CDJ86606.1 - 1.3e-27 96.8 0.0 2.5e-27 95.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Gp45_2 PF17470.2 CDJ86606.1 - 0.0052 16.7 0.0 0.05 13.6 0.0 2.5 2 0 0 2 2 2 1 Phage gene product 45.2 DUF5505 PF17610.2 CDJ86606.1 - 0.041 13.9 0.3 0.12 12.3 0.0 1.9 3 0 0 3 3 3 0 Family of unknown function (DUF5505) N_formyltrans_C PF18216.1 CDJ86606.1 - 0.11 12.2 0.0 0.33 10.6 0.0 1.8 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain zf-H2C2_2 PF13465.6 CDJ86607.1 - 7.4e-31 105.2 29.9 6.5e-08 32.7 0.7 5.5 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2 PF00096.26 CDJ86607.1 - 3.8e-21 74.3 35.3 4.1e-05 23.8 3.5 5.5 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ86607.1 - 1.3e-15 56.7 32.0 0.0017 19.0 1.9 5.6 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDJ86607.1 - 5.1e-11 42.3 31.1 0.00027 20.8 1.0 5.2 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ86607.1 - 1e-07 32.0 15.8 0.0032 17.7 0.1 5.0 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDJ86607.1 - 1.5e-05 25.2 22.0 0.0015 18.9 0.4 5.5 5 0 0 5 5 5 2 Zinc-finger of C2H2 type BolA PF01722.18 CDJ86607.1 - 0.011 16.0 1.5 0.28 11.5 0.2 3.1 2 1 1 3 3 3 0 BolA-like protein SET PF00856.28 CDJ86607.1 - 0.012 16.0 0.0 0.04 14.3 0.0 1.9 1 0 0 1 1 1 0 SET domain Zn-ribbon_8 PF09723.10 CDJ86607.1 - 0.013 15.6 12.4 3.7 7.7 2.1 4.3 2 1 2 4 4 4 0 Zinc ribbon domain DZR PF12773.7 CDJ86607.1 - 0.014 15.4 11.2 0.12 12.4 0.3 3.1 2 1 0 2 2 2 0 Double zinc ribbon zf-C2HE PF16278.5 CDJ86607.1 - 0.019 15.4 25.1 0.18 12.3 1.5 5.0 1 1 4 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 CDJ86607.1 - 0.095 12.5 14.6 6 6.7 0.7 4.4 4 0 0 4 4 4 0 zinc-finger C2H2-type C1_4 PF07975.12 CDJ86607.1 - 0.41 10.9 15.7 2.1 8.7 0.1 3.8 2 1 1 3 3 3 0 TFIIH C1-like domain zf-C2H2_2 PF12756.7 CDJ86607.1 - 2.2 8.7 20.1 7.5 7.0 0.5 4.3 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) DUF4428 PF14471.6 CDJ86607.1 - 2.6 8.0 9.5 2.2 8.3 0.3 3.6 4 0 0 4 4 3 0 Domain of unknown function (DUF4428) zf-H2C2_5 PF13909.6 CDJ86607.1 - 2.6 7.9 16.8 1.3 8.9 2.4 3.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zinc_ribbon_10 PF10058.9 CDJ86607.1 - 2.7 7.8 8.8 2.5 7.9 1.4 2.7 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein PHF5 PF03660.14 CDJ86607.1 - 4.2 7.6 6.9 30 4.9 1.6 2.6 1 1 1 2 2 2 0 PHF5-like protein zf-trcl PF13451.6 CDJ86607.1 - 4.7 7.2 16.5 0.59 10.1 1.1 4.9 5 0 0 5 5 5 0 Probable zinc-ribbon domain FYVE PF01363.21 CDJ86607.1 - 5.1 7.3 20.2 1.8e+04 -5.4 20.2 3.6 1 1 0 1 1 0 0 FYVE zinc finger GAGA PF09237.11 CDJ86607.1 - 5.4 6.9 7.5 2.2 8.1 0.4 3.2 1 1 2 3 3 3 0 GAGA factor zf-BED PF02892.15 CDJ86607.1 - 7.9 6.6 23.2 5 7.2 7.3 4.3 2 1 1 3 3 3 0 BED zinc finger Granulin PF00396.18 CDJ86608.1 - 2.2e-39 133.5 90.4 7.1e-17 61.5 22.5 5.0 4 1 1 5 5 5 4 Granulin CC PF04942.14 CDJ86609.1 - 2.3e-12 46.9 118.6 3.8e-05 23.8 9.7 8.8 7 1 1 8 8 8 6 CC domain MFS_1 PF07690.16 CDJ86610.1 - 1.9e-28 99.4 30.5 1.9e-23 83.0 16.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 CDJ86611.1 - 4.4e-15 55.5 15.1 7.2e-12 44.9 12.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF19 PF01579.18 CDJ86612.1 - 2.1e-09 37.4 4.3 2.5e-09 37.1 4.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF19) CPG4 PF15481.6 CDJ86612.1 - 1e-07 32.5 3.4 2.4e-07 31.3 0.4 2.2 1 1 1 2 2 2 1 Chondroitin proteoglycan 4 DUF1397 PF07165.11 CDJ86612.1 - 0.034 13.6 7.6 18 4.7 7.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1397) TBCC PF07986.12 CDJ86612.1 - 0.037 13.8 0.2 2.2 8.1 0.1 2.2 1 1 0 2 2 2 0 Tubulin binding cofactor C Fer4_21 PF14697.6 CDJ86612.1 - 2.5 8.3 5.7 1.3 9.2 1.5 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Ets PF00178.22 CDJ86613.1 - 8.5e-35 119.1 0.7 1.5e-34 118.3 0.7 1.4 1 0 0 1 1 1 1 Ets-domain Ets PF00178.22 CDJ86614.1 - 3.2e-30 104.4 1.9 6.3e-30 103.5 1.9 1.5 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 CDJ86614.1 - 1.2e-14 54.0 0.2 4.8e-14 52.1 0.1 2.0 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 CDJ86614.1 - 0.013 15.2 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAP25 PF15476.6 CDJ86614.1 - 0.018 14.7 0.4 0.04 13.6 0.4 1.5 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP25 TTR-52 PF01060.23 CDJ86615.1 - 1.6e-55 185.7 0.0 2.1e-27 95.6 0.0 2.3 2 0 0 2 2 2 2 Transthyretin-like family CarboxypepD_reg PF13620.6 CDJ86615.1 - 0.0012 19.1 0.0 2.3 8.5 0.0 2.4 2 0 0 2 2 2 2 Carboxypeptidase regulatory-like domain Transthyretin PF00576.21 CDJ86615.1 - 0.013 16.2 0.0 4 8.2 0.0 2.6 3 1 0 3 3 3 0 HIUase/Transthyretin family CarbopepD_reg_2 PF13715.6 CDJ86615.1 - 0.15 12.1 0.0 3.1 7.9 0.0 2.3 2 0 0 2 2 2 0 CarboxypepD_reg-like domain Papilloma_E5A PF05776.12 CDJ86616.1 - 0.28 11.6 12.0 0.38 11.2 12.0 1.3 1 0 0 1 1 1 0 Papillomavirus E5A protein ubiquitin PF00240.23 CDJ86617.1 - 1.8e-34 117.3 0.4 2.6e-34 116.8 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CDJ86617.1 - 1.1e-30 105.3 11.0 1.6e-30 104.7 11.0 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CDJ86617.1 - 2.2e-16 59.4 1.8 2.6e-16 59.2 0.5 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDJ86617.1 - 1.5e-05 25.4 0.1 6.5e-05 23.3 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 CDJ86617.1 - 0.0029 17.9 0.1 0.0053 17.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDJ86617.1 - 0.0047 17.0 0.1 0.0091 16.1 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 CDJ86617.1 - 0.0056 16.6 0.0 0.0073 16.2 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 CDJ86617.1 - 0.015 15.3 1.2 4.2 7.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 CDJ86617.1 - 0.023 15.3 0.1 0.029 14.9 0.1 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain FRG1 PF06229.12 CDJ86618.1 - 9e-63 211.4 0.3 1.3e-62 210.9 0.3 1.2 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 CDJ86618.1 - 4e-07 30.2 0.0 2.5e-06 27.7 0.0 2.2 2 1 0 2 2 2 1 Fascin domain DUF1754 PF08555.10 CDJ86618.1 - 0.0012 19.6 4.0 0.0012 19.6 4.0 1.8 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) RE_ScaI PF09569.10 CDJ86618.1 - 0.051 13.3 0.2 0.099 12.4 0.2 1.4 1 0 0 1 1 1 0 ScaI restriction endonuclease Not1 PF04054.15 CDJ86619.1 - 4.6e-122 407.5 1.2 4.6e-122 407.5 1.2 1.7 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 CDJ86619.1 - 6.9e-79 264.4 4.7 7.2e-79 264.3 3.0 2.0 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 CDJ86619.1 - 4.5e-41 140.2 6.2 1.2e-40 138.9 6.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) BAR_3 PF16746.5 CDJ86619.1 - 0.046 13.4 0.3 3.4 7.3 0.0 2.5 2 0 0 2 2 2 0 BAR domain of APPL family Nse4_C PF08743.10 CDJ86620.1 - 6.6e-26 90.4 1.1 1.1e-25 89.7 0.1 1.9 2 0 0 2 2 2 1 Nse4 C-terminal UBA_e1_thiolCys PF10585.9 CDJ86620.1 - 0.052 13.5 0.6 0.12 12.3 0.1 1.7 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site Kelch_1 PF01344.25 CDJ86622.1 - 3.9e-28 96.8 2.4 4.1e-13 48.7 0.2 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 CDJ86622.1 - 2.1e-13 50.0 0.0 2e-05 24.7 0.0 2.4 1 1 1 2 2 2 2 Kelch motif Kelch_2 PF07646.15 CDJ86622.1 - 5.8e-11 41.9 1.1 0.00036 20.4 0.1 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 CDJ86622.1 - 9.5e-11 41.5 0.0 1.3e-05 25.1 0.1 2.2 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ86622.1 - 5.2e-06 26.6 3.3 0.029 14.7 0.1 2.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ86622.1 - 0.0077 16.2 0.4 0.14 12.2 0.1 2.2 2 0 0 2 2 2 1 Kelch motif RVT_1 PF00078.27 CDJ86623.1 - 3e-22 79.2 0.0 3.5e-12 46.3 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Zot PF05707.12 CDJ86623.1 - 0.0028 17.3 0.2 2.9 7.5 0.0 2.5 1 1 0 2 2 2 2 Zonular occludens toxin (Zot) Med29 PF11568.8 CDJ86623.1 - 0.012 15.8 0.0 8.6 6.6 0.0 2.6 2 0 0 2 2 2 0 Mediator complex subunit 29 DUF4574 PF15141.6 CDJ86623.1 - 0.028 14.3 0.0 12 5.9 0.0 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Kelch_1 PF01344.25 CDJ86624.1 - 1.2e-66 220.1 7.7 6.7e-13 48.0 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CDJ86624.1 - 3.2e-41 138.3 2.1 2.2e-09 37.3 0.0 6.5 1 1 5 6 6 6 6 Kelch motif BACK PF07707.15 CDJ86624.1 - 4.5e-35 119.9 1.1 4.5e-35 119.9 1.1 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 CDJ86624.1 - 1.6e-28 99.2 0.4 2.9e-28 98.3 0.4 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 CDJ86624.1 - 2.9e-27 93.6 2.6 3.1e-07 30.1 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 CDJ86624.1 - 1.5e-23 82.5 0.5 7.5e-05 22.7 0.0 6.1 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ86624.1 - 6.6e-17 61.4 4.1 0.00028 21.1 0.0 5.9 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ86624.1 - 5.9e-08 32.5 4.3 0.011 15.7 0.0 5.5 6 0 0 6 6 6 2 Kelch motif AhpC-TSA PF00578.21 CDJ86626.1 - 1.1e-36 125.5 0.0 2.8e-36 124.2 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA family DUF1604 PF07713.13 CDJ86626.1 - 1.6e-34 117.6 1.0 4.3e-34 116.2 1.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) Redoxin PF08534.10 CDJ86626.1 - 8.4e-14 51.5 0.0 1.8e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CDJ86626.1 - 7.9e-09 35.2 0.0 1.8e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin G-patch PF01585.23 CDJ86626.1 - 3e-07 30.2 0.1 7.8e-07 28.9 0.1 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CDJ86626.1 - 0.019 15.0 0.1 0.019 15.0 0.1 2.2 2 0 0 2 2 2 0 G-patch domain RRM_1 PF00076.22 CDJ86627.1 - 4.9e-20 71.1 0.2 8e-20 70.4 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ86627.1 - 6.2e-05 22.6 0.0 8.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ86627.1 - 0.00018 21.3 0.0 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 CDJ86627.1 - 0.0011 19.0 0.1 0.0022 18.0 0.1 1.5 1 0 0 1 1 1 1 RNA binding motif Limkain-b1 PF11608.8 CDJ86627.1 - 0.042 13.9 0.0 0.083 13.0 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 SNF5 PF04855.12 CDJ86628.1 - 8.7e-53 179.5 0.0 4.1e-29 102.0 0.0 2.1 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 Auto_anti-p27 PF06677.12 CDJ86629.1 - 3 8.1 6.9 0.43 10.8 1.8 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) RhoGAP PF00620.27 CDJ86630.1 - 3.4e-49 166.6 0.1 5.9e-49 165.8 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain HTH_48 PF17906.1 CDJ86632.1 - 1e-11 44.7 0.7 1.7e-11 44.1 0.0 1.7 2 0 0 2 2 2 1 HTH domain in Mos1 transposase HTH_28 PF13518.6 CDJ86632.1 - 0.00016 21.7 2.8 0.088 12.9 0.0 2.8 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_Tnp_IS630 PF01710.16 CDJ86632.1 - 0.0004 20.4 5.0 0.0015 18.6 4.6 1.9 1 1 0 1 1 1 1 Transposase HTH_11 PF08279.12 CDJ86632.1 - 0.00048 20.0 0.0 0.0013 18.6 0.0 1.8 1 0 0 1 1 1 1 HTH domain FeoC PF09012.10 CDJ86632.1 - 0.001 19.1 0.0 0.0019 18.2 0.0 1.5 1 0 0 1 1 1 1 FeoC like transcriptional regulator HTH_24 PF13412.6 CDJ86632.1 - 0.003 17.1 0.0 0.0057 16.2 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 CDJ86632.1 - 0.035 13.9 0.1 5.9 6.8 0.0 3.1 3 0 0 3 3 3 0 Homeodomain-like domain HTH_DeoR PF08220.12 CDJ86632.1 - 0.05 13.4 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_32 PF13565.6 CDJ86632.1 - 0.18 12.4 2.3 0.47 11.1 0.1 2.2 2 0 0 2 2 2 0 Homeodomain-like domain Galactosyl_T PF01762.21 CDJ86633.1 - 2.8e-36 125.2 0.1 3.7e-36 124.8 0.1 1.1 1 0 0 1 1 1 1 Galactosyltransferase Smg8_Smg9 PF10220.9 CDJ86634.1 - 6.5 4.9 14.6 11 4.2 14.6 1.2 1 0 0 1 1 1 0 Smg8_Smg9 Zip PF02535.22 CDJ86634.1 - 6.6 5.8 9.3 11 5.1 9.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Menin PF05053.13 CDJ86634.1 - 9.4 4.5 11.5 13 4.0 11.5 1.1 1 0 0 1 1 1 0 Menin Fungal_TACC PF12709.7 CDJ86635.1 - 0.43 11.1 15.9 0.15 12.5 2.6 3.6 3 2 1 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins YabA PF06156.13 CDJ86635.1 - 1.3 9.7 13.2 2 9.1 0.1 3.2 3 0 0 3 3 3 0 Initiation control protein YabA Lectin_N PF03954.14 CDJ86635.1 - 2.1 8.1 10.2 5.5 6.7 0.2 3.2 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain Vir_act_alpha_C PF10400.9 CDJ86635.1 - 2.8 8.7 9.0 16 6.3 0.2 3.5 3 1 0 3 3 3 0 Virulence activator alpha C-term DUF2205 PF10224.9 CDJ86635.1 - 6.4 6.8 18.8 0.74 9.8 0.2 4.0 3 1 0 3 3 3 0 Short coiled-coil protein Mon1 PF03164.14 CDJ86636.1 - 1.1e-95 321.1 0.6 1.4e-95 320.8 0.6 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 MADF_DNA_bdg PF10545.9 CDJ86637.1 - 0.00031 21.0 0.0 0.00047 20.4 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF229 PF02995.17 CDJ86638.1 - 2.7e-52 178.0 1.1 6.6e-52 176.7 1.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF229) PNMA PF14893.6 CDJ86639.1 - 0.047 13.1 0.1 0.065 12.6 0.1 1.2 1 0 0 1 1 1 0 PNMA DUF229 PF02995.17 CDJ86642.1 - 4.7e-13 48.6 0.0 4.7e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Pro_isomerase PF00160.21 CDJ86643.1 - 1.8e-54 184.3 0.0 2.2e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Autophagy_N PF03986.13 CDJ86644.1 - 5.8e-48 162.3 0.1 9.3e-48 161.6 0.1 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 CDJ86644.1 - 1.8e-17 63.6 1.4 4.8e-17 62.3 1.1 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 CDJ86644.1 - 3.8e-15 55.1 1.8 4e-15 55.0 0.6 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein C-terminal Innate_immun PF12782.7 CDJ86644.1 - 0.12 11.9 1.5 0.19 11.2 1.5 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family 5_nucleotid PF05761.14 CDJ86645.1 - 1.9e-138 462.2 0.1 2.3e-138 461.9 0.1 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.6 CDJ86645.1 - 0.0011 19.1 0.0 0.02 15.0 0.0 2.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CDJ86645.1 - 0.17 12.0 0.0 0.47 10.6 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase zf-C2H2_jaz PF12171.8 CDJ86646.1 - 8.4e-09 35.5 2.2 8.4e-09 35.5 2.2 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-RRPl_C4 PF17026.5 CDJ86646.1 - 0.052 13.7 0.5 0.082 13.0 0.5 1.4 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type CAF1 PF04857.20 CDJ86647.1 - 1.2e-21 77.3 0.3 1.3e-12 47.6 0.0 2.4 2 1 0 2 2 2 2 CAF1 family ribonuclease TRAP-delta PF05404.12 CDJ86648.1 - 3.6e-51 172.9 1.4 4.2e-51 172.7 1.4 1.0 1 0 0 1 1 1 1 Translocon-associated protein, delta subunit precursor (TRAP-delta) DUF1279 PF06916.13 CDJ86649.1 - 1.6e-19 70.2 1.5 2.6e-19 69.5 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) PIG-P PF08510.12 CDJ86649.1 - 0.05 13.5 4.1 0.044 13.7 2.3 1.9 1 1 1 2 2 2 0 PIG-P CN_hydrolase PF00795.22 CDJ86650.1 - 4.6e-68 229.4 0.0 5.8e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase HIT PF01230.23 CDJ86650.1 - 1.3e-21 77.1 0.6 2.5e-21 76.2 0.6 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CDJ86650.1 - 3.5e-07 30.7 0.1 7.7e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GalP_UDP_tr_C PF02744.17 CDJ86650.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain CN_hydrolase PF00795.22 CDJ86651.1 - 6.5e-61 205.9 0.0 8.4e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase HIT PF01230.23 CDJ86651.1 - 9.6e-22 77.6 0.3 2.4e-21 76.3 0.3 1.7 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CDJ86651.1 - 3.5e-07 30.7 0.1 1.1e-06 29.1 0.0 1.9 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding Ank_4 PF13637.6 CDJ86652.1 - 4.3e-08 33.6 0.1 0.00088 19.8 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CDJ86652.1 - 5.6e-06 26.6 0.3 0.012 16.1 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 CDJ86652.1 - 4.1e-05 23.6 0.3 0.0039 17.6 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 CDJ86652.1 - 8.5e-05 23.1 0.1 0.00031 21.3 0.0 1.8 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ86652.1 - 0.0085 16.4 0.3 0.052 13.9 0.2 2.3 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Innexin PF00876.18 CDJ86654.1 - 2.9e-40 138.7 7.8 3.3e-40 138.5 7.8 1.0 1 0 0 1 1 1 1 Innexin Ephrin_rec_like PF07699.13 CDJ86655.1 - 0.011 15.5 8.4 0.022 14.5 2.9 6.6 5 2 2 7 7 7 0 Putative ephrin-receptor like NCD3G PF07562.14 CDJ86655.1 - 1.8 8.6 34.8 0.14 12.1 3.7 5.8 6 1 0 6 6 6 0 Nine Cysteines Domain of family 3 GPCR Neur_chan_LBD PF02931.23 CDJ86656.1 - 1.3e-39 135.9 0.7 1.6e-39 135.6 0.7 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ86656.1 - 1.2e-20 74.6 6.0 7.6e-18 65.4 3.6 2.2 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DEAD PF00270.29 CDJ86657.1 - 1.3e-47 161.8 0.1 2.8e-47 160.7 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ86657.1 - 1.1e-10 41.7 0.7 3.2e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDJ86657.1 - 3e-08 34.0 0.2 3.8e-07 30.4 0.2 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain PIEZO PF15917.5 CDJ86657.1 - 0.041 13.4 3.4 0.069 12.6 3.4 1.3 1 0 0 1 1 1 0 Piezo AAA_22 PF13401.6 CDJ86657.1 - 0.051 13.9 0.4 0.2 12.0 0.4 2.0 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 CDJ86657.1 - 0.29 10.4 8.9 0.93 8.8 0.0 2.5 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF5301 PF17225.3 CDJ86657.1 - 0.79 10.2 4.7 1.5 9.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5300) Archease PF01951.16 CDJ86658.1 - 3.8e-36 124.4 0.2 4.6e-36 124.1 0.2 1.1 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) Transglut_core PF01841.19 CDJ86660.1 - 0.0063 17.0 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily CC2D2AN-C2 PF15625.6 CDJ86661.1 - 5.5e-17 62.0 0.2 2e-16 60.2 0.2 1.9 1 1 0 1 1 1 1 CC2D2A N-terminal C2 domain Scramblase PF03803.15 CDJ86662.1 - 9.6e-68 227.8 0.0 1.2e-67 227.5 0.0 1.0 1 0 0 1 1 1 1 Scramblase DUF2243 PF10002.9 CDJ86662.1 - 0.043 13.9 0.0 0.06 13.4 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2243) FA_hydroxylase PF04116.13 CDJ86663.1 - 2e-24 86.4 9.4 2e-24 86.4 9.4 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ion_trans_2 PF07885.16 CDJ86664.1 - 7.5e-30 102.7 16.3 9.9e-18 63.9 2.6 2.5 2 0 0 2 2 2 2 Ion channel IRK PF01007.20 CDJ86664.1 - 0.009 15.8 2.8 2.1 8.2 0.6 2.7 2 1 0 2 2 2 2 Inward rectifier potassium channel transmembrane domain Lig_chan PF00060.26 CDJ86664.1 - 0.18 11.6 0.3 0.61 9.9 0.3 1.8 1 1 0 1 1 1 0 Ligand-gated ion channel DUF1853 PF08907.11 CDJ86665.1 - 0.047 13.4 0.3 0.07 12.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1853) Barwin PF00967.17 CDJ86666.1 - 0.0069 16.2 0.2 0.017 15.0 0.0 1.7 2 0 0 2 2 2 1 Barwin family Rotamase_3 PF13616.6 CDJ86666.1 - 0.097 13.2 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 PPIC-type PPIASE domain RVT_1 PF00078.27 CDJ86668.1 - 7.5e-08 32.2 0.0 1.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Resolvase PF00239.21 CDJ86668.1 - 0.095 12.8 0.4 0.16 12.1 0.4 1.3 1 0 0 1 1 1 0 Resolvase, N terminal domain PDZ PF00595.24 CDJ86669.1 - 2.5e-06 27.7 0.0 5.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDJ86669.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 PDZ domain RVT_1 PF00078.27 CDJ86670.1 - 5.7e-39 133.9 0.1 1.1e-38 133.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GILT PF03227.16 CDJ86670.1 - 0.064 13.5 0.7 0.19 12.0 0.3 2.0 2 0 0 2 2 2 0 Gamma interferon inducible lysosomal thiol reductase (GILT) Hemolysin_N PF12563.8 CDJ86670.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Hemolytic toxin N terminal Ank_4 PF13637.6 CDJ86671.1 - 1e-28 99.3 4.7 9.6e-10 38.8 0.2 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ86671.1 - 1.1e-28 99.6 1.5 2.5e-16 60.0 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ86671.1 - 5.5e-21 74.4 1.6 2.2e-11 43.8 0.1 3.4 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CDJ86671.1 - 9.1e-20 70.2 0.3 1.6e-07 31.4 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 CDJ86671.1 - 3.1e-19 67.1 0.2 5.5e-06 26.3 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat MCC-bdg_PDZ PF10506.9 CDJ86671.1 - 0.048 13.7 0.1 0.21 11.6 0.0 2.0 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome ETF PF01012.21 CDJ86672.1 - 1.4e-37 129.4 4.4 2.1e-37 128.8 4.4 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 CDJ86672.1 - 4.2e-37 126.1 0.9 4.2e-37 126.1 0.9 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain Fasciclin PF02469.22 CDJ86674.1 - 4e-14 52.9 0.0 1.7e-08 34.7 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain LRR_8 PF13855.6 CDJ86676.1 - 1.6e-14 53.4 12.2 1.2e-06 28.2 5.2 3.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CDJ86676.1 - 2.8e-13 49.8 9.1 2.4e-05 24.6 0.5 3.6 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CDJ86676.1 - 6e-08 32.1 5.1 2.2 8.6 0.1 5.8 6 0 0 6 6 6 3 Leucine Rich repeat Ig_3 PF13927.6 CDJ86676.1 - 4.4e-07 30.4 0.0 8.1e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain LRR_1 PF00560.33 CDJ86676.1 - 8.9e-07 28.6 6.1 3.4 8.6 0.0 6.1 4 2 0 4 4 4 3 Leucine Rich Repeat I-set PF07679.16 CDJ86676.1 - 1.4e-05 25.1 0.0 3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_9 PF14580.6 CDJ86676.1 - 0.0027 17.2 0.2 0.0067 15.9 0.2 1.6 1 1 0 1 1 1 1 Leucine-rich repeat ig PF00047.25 CDJ86676.1 - 0.0042 17.2 0.0 0.0087 16.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CDJ86676.1 - 0.025 14.9 0.0 0.075 13.4 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin domain Mucin PF01456.17 CDJ86676.1 - 0.2 11.7 0.7 0.39 10.7 0.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein MH2 PF03166.14 CDJ86677.1 - 8.6e-60 202.1 0.0 1.6e-59 201.3 0.0 1.5 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 CDJ86677.1 - 2.2e-21 76.0 2.4 2.2e-21 76.0 2.4 2.8 3 0 0 3 3 3 1 MH1 domain ANAPC4_WD40 PF12894.7 CDJ86677.1 - 2.3e-08 34.2 1.3 0.14 12.5 0.0 5.0 5 0 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Bap31_Bap29_C PF18035.1 CDJ86678.1 - 0.0033 17.4 1.5 0.03 14.3 0.2 3.0 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain Cep57_MT_bd PF06657.13 CDJ86678.1 - 0.044 14.2 1.9 0.039 14.4 4.4 2.2 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF4407 PF14362.6 CDJ86678.1 - 0.051 12.9 5.9 0.087 12.2 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prefoldin PF02996.17 CDJ86678.1 - 0.071 13.0 6.6 0.1 12.5 2.7 2.3 1 1 1 2 2 2 0 Prefoldin subunit LXG PF04740.12 CDJ86678.1 - 0.11 12.1 4.5 0.22 11.2 4.5 1.4 1 0 0 1 1 1 0 LXG domain of WXG superfamily Spc7 PF08317.11 CDJ86678.1 - 0.13 11.2 7.5 0.22 10.4 7.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 CDJ86678.1 - 0.29 11.2 2.1 0.73 9.9 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 CDJ86678.1 - 0.63 10.2 7.0 0.23 11.7 3.4 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family UPF0449 PF15136.6 CDJ86678.1 - 0.72 10.4 5.6 0.94 10.0 0.4 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 ISG65-75 PF11727.8 CDJ86678.1 - 1.2 8.3 6.6 2.9 7.1 6.6 1.6 1 0 0 1 1 1 0 Invariant surface glycoprotein ApoL PF05461.11 CDJ86681.1 - 1.6e-13 50.7 7.1 2.2e-13 50.2 7.1 1.1 1 0 0 1 1 1 1 Apolipoprotein L HDV_ag PF01517.18 CDJ86681.1 - 0.047 13.5 0.0 0.88 9.3 0.0 2.1 2 0 0 2 2 2 0 Hepatitis delta virus delta antigen DivIVA PF05103.13 CDJ86681.1 - 0.11 12.6 1.0 0.19 11.8 0.4 1.7 2 0 0 2 2 2 0 DivIVA protein DUF4781 PF16013.5 CDJ86681.1 - 2.2 7.0 6.2 0.75 8.6 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) DUF1759 PF03564.15 CDJ86682.1 - 6.3e-23 81.4 0.9 1.8e-22 79.9 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 CDJ86682.1 - 1.6e-12 47.5 0.0 3.6e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) gag-asp_proteas PF13975.6 CDJ86682.1 - 6e-06 26.7 0.1 7.3e-05 23.3 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ86682.1 - 0.00069 20.2 0.0 0.0022 18.6 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 CDJ86682.1 - 0.00082 19.4 1.5 0.00082 19.4 1.5 2.6 2 0 0 2 2 2 1 Zinc knuckle RVP_2 PF08284.11 CDJ86682.1 - 0.0089 15.8 0.0 0.03 14.1 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease HrpJ PF07201.11 CDJ86682.1 - 0.89 9.8 4.9 0.2 12.0 0.3 2.1 2 0 0 2 2 2 0 HrpJ-like domain ArfGap PF01412.18 CDJ86684.1 - 6.6e-30 103.6 1.8 6.6e-30 103.6 1.8 2.1 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf Taxilin PF09728.9 CDJ86684.1 - 0.11 11.7 2.9 0.23 10.6 0.0 2.2 2 0 0 2 2 2 0 Myosin-like coiled-coil protein zf-dskA_traR PF01258.17 CDJ86684.1 - 1.5 8.8 5.0 6.9 6.7 0.3 3.0 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger zf-C4 PF00105.18 CDJ86685.1 - 9.1e-27 93.3 13.5 9.1e-27 93.3 13.5 2.2 2 0 0 2 2 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ86685.1 - 3.7e-18 65.9 1.8 4.7e-18 65.5 0.0 2.0 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor TFIIA PF03153.13 CDJ86685.1 - 0.0044 17.1 21.0 0.0067 16.5 21.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ86685.1 - 0.0056 16.3 22.8 0.011 15.4 22.8 1.4 1 0 0 1 1 1 1 Spt20 family CCDC53 PF10152.9 CDJ86685.1 - 0.02 15.3 3.5 0.078 13.4 3.4 2.0 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF4175 PF13779.6 CDJ86685.1 - 0.062 11.2 12.9 0.093 10.6 12.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PAT1 PF09770.9 CDJ86685.1 - 0.1 10.9 12.4 0.39 8.9 10.8 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Suf PF05843.14 CDJ86685.1 - 0.41 10.6 12.8 0.65 9.9 12.8 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Androgen_recep PF02166.16 CDJ86685.1 - 0.64 8.8 24.0 1.2 7.8 24.0 1.4 1 0 0 1 1 1 0 Androgen receptor Presenilin PF01080.17 CDJ86685.1 - 0.72 8.6 5.8 1.1 7.9 5.8 1.2 1 0 0 1 1 1 0 Presenilin DUF3464 PF11947.8 CDJ86685.1 - 1 9.1 5.1 2.3 8.0 5.1 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Neur_chan_memb PF02932.16 CDJ86685.1 - 1.1 9.2 4.2 2.2 8.3 4.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2722 PF10846.8 CDJ86685.1 - 1.9 7.3 24.8 3.5 6.5 24.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) NIDO PF06119.14 CDJ86686.1 - 1.5e-16 61.1 0.8 2.7e-16 60.3 0.8 1.4 1 0 0 1 1 1 1 Nidogen-like EGF_CA PF07645.15 CDJ86686.1 - 5.1e-08 33.0 5.2 5.1e-08 33.0 5.2 4.2 3 1 1 4 4 4 1 Calcium-binding EGF domain EGF_3 PF12947.7 CDJ86686.1 - 3e-06 27.3 5.0 3e-06 27.3 5.0 4.5 3 1 0 4 4 4 2 EGF domain EGF PF00008.27 CDJ86686.1 - 1.6e-05 25.1 9.6 1.6e-05 25.1 9.6 4.1 4 1 0 4 4 4 1 EGF-like domain cEGF PF12662.7 CDJ86686.1 - 0.0001 22.2 2.4 0.0001 22.2 2.4 3.3 3 0 0 3 3 3 2 Complement Clr-like EGF-like hEGF PF12661.7 CDJ86686.1 - 0.0032 18.0 4.0 0.0032 18.0 4.0 4.6 4 0 0 4 4 4 1 Human growth factor-like EGF CYTH PF01928.21 CDJ86687.1 - 1.6e-09 37.9 0.0 2.1e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 CYTH domain Cytochrom_B561 PF03188.16 CDJ86688.1 - 2.6e-08 34.1 5.3 2.6e-08 34.1 5.3 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.17 CDJ86688.1 - 0.014 15.6 0.0 0.03 14.6 0.0 1.5 1 1 0 1 1 1 0 DOMON domain DUF998 PF06197.13 CDJ86688.1 - 0.96 9.0 22.0 9.1 5.8 16.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF998) DUF4293 PF14126.6 CDJ86688.1 - 4.1 7.6 12.6 1.9 8.7 5.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) DUF3585 PF12130.8 CDJ86690.1 - 3.1e-07 30.6 13.4 4.6e-07 30.0 8.9 3.3 2 0 0 2 2 2 1 Bivalent Mical/EHBP Rab binding domain CH PF00307.31 CDJ86690.1 - 1.9e-06 28.0 0.0 5.7e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain Pyr_redox_2 PF07992.14 CDJ86690.1 - 1.8e-05 24.2 0.0 3.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CDJ86690.1 - 0.00012 21.3 0.0 0.00019 20.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 CDJ86690.1 - 0.00021 20.7 0.0 0.00053 19.3 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 CDJ86690.1 - 0.00083 18.2 0.0 0.0014 17.4 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 CDJ86690.1 - 0.0026 18.3 0.1 0.0089 16.6 0.0 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase LIM PF00412.22 CDJ86690.1 - 0.0046 17.2 7.2 0.012 15.9 7.2 1.7 1 0 0 1 1 1 1 LIM domain Lycopene_cycl PF05834.12 CDJ86690.1 - 0.0048 16.0 0.0 0.0076 15.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 CDJ86690.1 - 0.0056 16.0 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CDJ86690.1 - 0.0087 15.2 0.6 0.028 13.5 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 CDJ86690.1 - 0.0091 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase CAMSAP_CH PF11971.8 CDJ86690.1 - 0.025 14.4 0.0 0.092 12.6 0.0 2.0 1 0 0 1 1 1 0 CAMSAP CH domain NAD_binding_8 PF13450.6 CDJ86690.1 - 0.047 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CDJ86690.1 - 0.052 13.1 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Rad50_zn_hook PF04423.14 CDJ86691.1 - 0.075 12.9 0.9 0.19 11.6 0.9 1.6 1 0 0 1 1 1 0 Rad50 zinc hook motif PDZ PF00595.24 CDJ86692.1 - 1.9e-07 31.3 0.0 8.7e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 CDJ86692.1 - 9.2e-05 22.2 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ86692.1 - 0.011 16.1 0.0 0.019 15.3 0.0 1.5 2 0 0 2 2 2 0 PDZ domain DUF3394 PF11874.8 CDJ86692.1 - 0.13 11.9 0.0 0.65 9.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3394) ASD2 PF08687.11 CDJ86694.1 - 3e-06 27.0 3.8 3e-06 27.0 3.8 1.4 2 0 0 2 2 2 1 Apx/Shroom domain ASD2 KMP11 PF03037.16 CDJ86694.1 - 0.078 13.8 1.1 0.16 12.7 1.1 1.5 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 FtsJ PF01728.19 CDJ86695.1 - 7.3e-60 202.1 0.2 1.2e-59 201.4 0.2 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.12 CDJ86695.1 - 1.3e-58 198.1 37.4 1.3e-58 198.1 37.4 4.9 2 1 2 4 4 4 1 Spb1 C-terminal domain DUF3381 PF11861.8 CDJ86695.1 - 3.6e-35 121.2 16.4 3.6e-35 121.2 16.4 5.3 4 1 2 6 6 6 1 Domain of unknown function (DUF3381) Ribosomal_S27 PF01599.19 CDJ86696.1 - 1.7e-24 85.7 3.8 1.7e-24 85.7 3.8 1.7 2 0 0 2 2 2 1 Ribosomal protein S27a ubiquitin PF00240.23 CDJ86696.1 - 5.4e-13 48.5 0.1 1.6e-12 47.0 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CDJ86696.1 - 0.0074 16.1 0.5 0.014 15.2 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 CDJ86696.1 - 0.045 13.7 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 CDJ86696.1 - 0.051 14.1 0.1 0.071 13.7 0.1 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Nucleoplasmin PF03066.15 CDJ86696.1 - 0.1 13.1 0.1 0.18 12.3 0.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin/nucleophosmin domain Ank_4 PF13637.6 CDJ86697.1 - 7.9e-29 99.7 1.6 1.1e-07 32.2 0.0 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Asparaginase_C PF17763.1 CDJ86697.1 - 1e-27 96.6 0.0 1.4e-26 92.9 0.0 2.4 2 1 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 CDJ86697.1 - 2.1e-24 85.9 5.0 1.8e-08 34.8 0.3 2.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ86697.1 - 4.4e-18 65.1 1.0 9e-09 35.4 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ86697.1 - 1.7e-15 55.5 0.6 1.9e-05 24.6 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 CDJ86697.1 - 5.7e-12 45.5 0.7 0.00012 22.4 0.3 3.5 3 0 0 3 3 3 2 Ankyrin repeat Sushi PF00084.20 CDJ86698.1 - 1.2e-37 128.3 28.0 8.7e-06 26.2 0.4 11.0 11 0 0 11 11 11 10 Sushi repeat (SCR repeat) Ig_3 PF13927.6 CDJ86698.1 - 0.072 13.7 3.9 1.4 9.6 0.1 4.8 6 1 0 6 6 6 0 Immunoglobulin domain Pkinase_Tyr PF07714.17 CDJ86699.1 - 6.5e-53 179.6 0.0 1e-52 179.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 CDJ86699.1 - 2.2e-49 165.9 9.3 3.1e-13 50.1 0.0 6.8 2 1 3 6 6 6 6 Ankyrin repeats (3 copies) Pkinase PF00069.25 CDJ86699.1 - 2e-45 155.2 0.0 3.8e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ank PF00023.30 CDJ86699.1 - 5.1e-42 140.5 20.2 2.5e-07 30.8 0.5 10.7 10 0 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.6 CDJ86699.1 - 3e-39 132.9 8.0 2.8e-10 40.5 0.0 8.3 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ86699.1 - 3.2e-39 128.4 6.2 4.2e-05 23.6 0.0 10.8 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 CDJ86699.1 - 6.2e-31 106.1 12.5 6.2e-07 29.6 0.0 8.7 4 2 5 9 9 9 7 Ankyrin repeats (many copies) Kdo PF06293.14 CDJ86699.1 - 0.00044 19.7 0.0 0.00085 18.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ86699.1 - 0.0052 16.7 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CDJ86699.1 - 0.026 14.1 0.1 0.074 12.6 0.0 1.7 1 1 0 2 2 2 0 RIO1 family Kinase-like PF14531.6 CDJ86699.1 - 0.081 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Tim29 PF10171.9 CDJ86700.1 - 5.4e-31 107.4 0.1 6.3e-31 107.1 0.1 1.0 1 0 0 1 1 1 1 Translocase of the Inner Mitochondrial membrane 29 DUF148 PF02520.17 CDJ86701.1 - 0.0027 17.8 1.3 0.0027 17.8 1.3 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF148 BPS1 PF05633.11 CDJ86701.1 - 0.028 13.4 0.6 0.028 13.4 0.6 1.5 2 0 0 2 2 2 0 Protein BYPASS1-related Gp-FAR-1 PF05823.12 CDJ86701.1 - 0.045 14.1 2.2 0.97 9.8 0.9 2.5 2 2 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) GPAT_N PF14829.6 CDJ86701.1 - 0.061 13.3 0.4 0.89 9.6 0.0 2.7 3 0 0 3 3 3 0 Glycerol-3-phosphate acyltransferase N-terminal Mit_ribos_Mrp51 PF11709.8 CDJ86701.1 - 0.18 11.3 2.1 0.21 11.1 2.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit CREPT PF16566.5 CDJ86702.1 - 4.7e-33 114.4 4.4 3.4e-32 111.7 5.0 2.0 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour CTD_bind PF04818.13 CDJ86702.1 - 7e-16 58.8 1.4 8.4e-15 55.3 0.1 3.2 4 1 0 4 4 4 1 RNA polymerase II-binding domain. DUF445 PF04286.12 CDJ86702.1 - 0.025 14.4 2.7 0.04 13.7 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF445) CDH1_2_SANT_HL1 PF18375.1 CDJ86702.1 - 0.13 13.0 0.7 0.33 11.7 0.6 1.8 1 1 0 1 1 1 0 CDH1/2 SANT-Helical linker 1 TMF_DNA_bd PF12329.8 CDJ86702.1 - 0.19 11.8 2.1 0.39 10.7 0.3 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding MSA-2c PF12238.8 CDJ86702.1 - 0.29 11.1 0.1 0.29 11.1 0.1 1.9 2 1 0 2 2 2 0 Merozoite surface antigen 2c BUD22 PF09073.10 CDJ86702.1 - 0.32 10.3 1.3 0.52 9.6 0.9 1.4 1 1 0 1 1 1 0 BUD22 MMR_HSR1_Xtn PF16897.5 CDJ86703.1 - 2e-44 149.9 0.9 4.2e-44 148.9 0.9 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CDJ86703.1 - 1.3e-22 79.6 0.1 2.5e-22 78.7 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CDJ86703.1 - 1.3e-20 73.6 0.0 2.4e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ86703.1 - 1.7e-11 43.9 0.0 2.8e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CDJ86703.1 - 0.0031 17.6 0.3 0.3 11.1 0.0 2.3 1 1 0 2 2 2 1 Dynamin family SafA PF17073.5 CDJ86703.1 - 0.049 13.6 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Two-component-system connector protein MeaB PF03308.16 CDJ86703.1 - 0.057 12.4 1.5 0.18 10.7 0.1 2.3 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TM2 PF05154.16 CDJ86704.1 - 5.5e-11 42.6 8.8 9.3e-11 41.9 8.8 1.4 1 0 0 1 1 1 1 TM2 domain Adap_comp_sub PF00928.21 CDJ86705.1 - 1.6e-75 253.9 0.1 2.4e-75 253.3 0.1 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CDJ86705.1 - 3.6e-07 30.2 0.1 9.5e-07 28.8 0.0 1.7 2 0 0 2 2 2 1 Clathrin adaptor complex small chain FANCAA PF15146.6 CDJ86707.1 - 0.049 12.7 0.1 0.08 12.0 0.1 1.2 1 0 0 1 1 1 0 Fanconi anemia-associated zf-C2H2_assoc2 PF16624.5 CDJ86710.1 - 0.8 10.8 3.0 0.55 11.3 0.6 2.0 2 0 0 2 2 2 0 Unstructured region upstream of a zinc-finger CAP PF00188.26 CDJ86711.1 - 6.6e-12 46.4 0.8 6.6e-12 46.4 0.8 2.5 2 1 0 2 2 2 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ86711.1 - 0.048 13.9 0.0 0.048 13.9 0.0 2.6 2 2 0 2 2 2 0 Ancylostoma-associated secreted protein related Mitofilin PF09731.9 CDJ86711.1 - 1.1 8.0 14.0 1.4 7.7 14.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CAP PF00188.26 CDJ86712.1 - 5.2e-06 27.3 0.3 7.2e-06 26.9 0.3 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Equine_IAV_S2 PF06502.11 CDJ86712.1 - 0.14 12.2 1.1 1.4 9.1 0.4 2.4 1 1 1 2 2 2 0 Equine infectious anaemia virus S2 protein CAP PF00188.26 CDJ86713.1 - 3.3e-11 44.1 0.2 3.3e-11 44.1 0.2 1.9 2 1 0 2 2 2 1 Cysteine-rich secretory protein family DUF966 PF06136.13 CDJ86713.1 - 0.68 9.6 9.7 0.87 9.2 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Hid1 PF12722.7 CDJ86713.1 - 1.3 7.0 5.3 1.3 7.1 5.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.9 CDJ86713.1 - 7.1 5.0 8.8 7.9 4.9 8.8 1.1 1 0 0 1 1 1 0 Macoilin family Dynactin PF12455.8 CDJ86715.1 - 9.2e-18 64.5 5.8 4.7e-17 62.2 0.0 2.9 3 0 0 3 3 3 1 Dynein associated protein HMMR_N PF15905.5 CDJ86715.1 - 1.9e-05 24.3 10.2 1.9e-05 24.3 10.2 2.9 3 0 0 3 3 3 1 Hyaluronan mediated motility receptor N-terminal GIT_CC PF16559.5 CDJ86715.1 - 0.13 12.1 3.1 0.68 9.8 3.1 2.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor LETM1 PF07766.13 CDJ86715.1 - 0.15 11.4 5.0 0.043 13.2 1.4 2.0 2 0 0 2 2 2 0 LETM1-like protein Glyco_tran_28_C PF04101.16 CDJ86715.1 - 0.31 11.0 8.3 1.3 9.0 0.0 3.1 3 1 0 3 3 3 0 Glycosyltransferase family 28 C-terminal domain MbeD_MobD PF04899.12 CDJ86715.1 - 3.5 7.8 10.0 0.17 12.0 2.1 2.8 2 0 0 2 2 2 0 MbeD/MobD like DASH_Dad4 PF08650.10 CDJ86715.1 - 7.4 6.6 6.7 8.3 6.5 0.4 3.5 2 1 1 3 3 3 0 DASH complex subunit Dad4 CD20 PF04103.15 CDJ86716.1 - 9.4e-07 29.0 14.3 1.4e-06 28.5 13.7 1.7 1 1 0 1 1 1 1 CD20-like family Phosphodiest PF01663.22 CDJ86717.1 - 7.8e-56 190.2 2.1 1.6e-55 189.2 2.1 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CDJ86717.1 - 0.0017 17.8 2.3 0.012 15.0 2.4 2.0 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 CDJ86717.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Phosphoesterase PF04185.14 CDJ86717.1 - 0.028 13.6 0.4 0.051 12.8 0.4 1.3 1 0 0 1 1 1 0 Phosphoesterase family TRIQK PF15168.6 CDJ86717.1 - 0.069 13.0 1.0 0.15 11.9 1.0 1.5 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family DUF1289 PF06945.13 CDJ86717.1 - 0.28 11.0 1.7 6.1 6.7 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) RVT_1 PF00078.27 CDJ86718.1 - 5.6e-15 55.4 0.0 9.8e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TB2_DP1_HVA22 PF03134.19 CDJ86719.1 - 3e-28 97.6 6.9 5.4e-28 96.7 6.9 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family LSM PF01423.22 CDJ86720.1 - 8.6e-22 76.6 0.0 1.2e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain SNF2_N PF00176.23 CDJ86722.1 - 1.5e-50 171.9 0.1 2.9e-50 171.0 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ86722.1 - 1.1e-11 45.0 0.0 7.8e-11 42.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ86722.1 - 2.4e-09 37.4 0.3 1.3e-08 35.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CDJ86722.1 - 0.012 15.9 0.2 0.18 12.1 0.1 3.1 2 1 0 2 2 2 0 AAA domain zf-C2H2 PF00096.26 CDJ86723.1 - 1.4e-14 53.6 15.9 0.001 19.4 0.4 5.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ86723.1 - 1.5e-13 50.4 32.6 9.3e-08 32.2 0.7 5.4 6 0 0 6 6 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDJ86723.1 - 8.6e-11 41.7 19.7 0.023 15.5 0.5 6.4 7 0 0 7 7 5 4 C2H2-type zinc finger zf-Di19 PF05605.12 CDJ86723.1 - 0.00088 19.5 13.4 0.024 14.9 0.7 3.4 2 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 CDJ86723.1 - 0.006 16.8 16.4 0.21 11.9 0.0 5.9 6 1 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CDJ86723.1 - 0.035 14.5 15.5 0.23 11.8 4.5 3.8 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) BolA PF01722.18 CDJ86723.1 - 0.035 14.4 0.1 0.083 13.2 0.1 1.6 1 0 0 1 1 1 0 BolA-like protein zf-met PF12874.7 CDJ86723.1 - 0.1 13.1 15.7 0.48 10.9 0.0 5.4 6 0 0 6 6 5 0 Zinc-finger of C2H2 type zf-CHY PF05495.12 CDJ86723.1 - 0.3 11.6 11.3 0.87 10.1 0.4 2.7 2 0 0 2 2 2 0 CHY zinc finger Zn-ribbon_8 PF09723.10 CDJ86723.1 - 0.36 11.0 10.4 0.37 10.9 1.2 3.1 2 1 1 3 3 3 0 Zinc ribbon domain Rad50_zn_hook PF04423.14 CDJ86723.1 - 0.76 9.7 0.1 0.76 9.7 0.1 3.7 4 0 0 4 4 4 0 Rad50 zinc hook motif Evr1_Alr PF04777.13 CDJ86723.1 - 0.82 10.2 5.4 6.7 7.2 3.8 2.9 1 1 1 2 2 2 0 Erv1 / Alr family Sgf11 PF08209.11 CDJ86723.1 - 1.2 8.8 10.3 2.3 7.9 0.1 3.8 4 0 0 4 4 3 0 Sgf11 (transcriptional regulation protein) zf-RING_7 PF02591.15 CDJ86723.1 - 1.2 9.4 9.5 11 6.3 1.4 3.8 3 0 0 3 3 3 0 C4-type zinc ribbon domain Cript PF10235.9 CDJ86723.1 - 5.5 7.6 11.8 5.7 7.6 0.5 3.2 2 1 1 3 3 3 0 Microtubule-associated protein CRIPT zf-C2HE PF16278.5 CDJ86723.1 - 5.7 7.5 6.9 9.5 6.8 1.4 3.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_15 PF17032.5 CDJ86723.1 - 6.8 7.5 14.3 9.5 7.1 2.6 3.6 2 1 2 4 4 3 0 zinc-ribbon family zf-C2HC_2 PF13913.6 CDJ86723.1 - 9.1 6.3 13.3 7 6.7 0.2 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type YyzF PF14116.6 CDJ86723.1 - 9.3 6.4 9.1 10 6.2 0.5 3.9 4 0 0 4 4 4 0 YyzF-like protein zf-BED PF02892.15 CDJ86723.1 - 9.6 6.3 21.5 2.3 8.3 3.7 4.8 2 1 3 5 5 5 0 BED zinc finger Rad50_zn_hook PF04423.14 CDJ86724.1 - 0.71 9.7 6.4 16 5.4 0.0 3.8 4 0 0 4 4 4 0 Rad50 zinc hook motif zf-Di19 PF05605.12 CDJ86724.1 - 0.99 9.7 4.4 1 9.7 0.7 2.8 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding OrfB_Zn_ribbon PF07282.11 CDJ86724.1 - 1.1 9.2 5.6 6.7 6.7 0.1 3.6 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Arm PF00514.23 CDJ86725.1 - 1.2e-26 91.8 16.6 1.3e-05 25.0 0.0 9.8 11 0 0 11 11 11 6 Armadillo/beta-catenin-like repeat Neurochondrin PF05536.11 CDJ86725.1 - 7.8e-07 27.8 5.8 0.0009 17.7 0.1 3.1 3 0 0 3 3 3 2 Neurochondrin Adaptin_N PF01602.20 CDJ86725.1 - 0.00018 20.2 6.9 0.21 10.1 6.4 3.3 2 1 0 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.6 CDJ86725.1 - 0.0022 18.5 6.7 1.6 9.4 0.0 5.7 6 0 0 6 6 6 1 HEAT-like repeat Proteasom_PSMB PF10508.9 CDJ86725.1 - 0.0027 16.3 1.9 5.1 5.5 0.0 4.0 2 1 1 4 4 4 2 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.6 CDJ86725.1 - 0.005 17.2 9.2 0.18 12.2 1.2 5.4 3 2 3 6 6 6 2 HEAT repeats RTTN_N PF14726.6 CDJ86725.1 - 0.035 14.9 0.2 2.5 9.0 0.0 3.5 4 1 0 4 4 4 0 Rotatin, an armadillo repeat protein, centriole functioning HEAT PF02985.22 CDJ86725.1 - 0.18 12.2 3.6 68 4.1 0.0 5.2 5 0 0 5 5 5 0 HEAT repeat Atx10homo_assoc PF09759.9 CDJ86725.1 - 0.28 11.2 2.0 12 6.0 0.3 3.0 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain MFS_5 PF05631.14 CDJ86726.1 - 3.1e-152 506.6 15.6 4.1e-152 506.2 15.6 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 CDJ86726.1 - 1.3e-22 80.2 51.0 1.1e-20 73.9 24.1 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily 7tm_3 PF00003.22 CDJ86727.1 - 4.7e-33 114.9 28.3 7.6e-33 114.2 28.3 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 CDJ86727.1 - 8.3e-22 77.8 0.4 9.6e-13 47.9 0.7 2.3 2 0 0 2 2 2 2 Receptor family ligand binding region Ric8 PF10165.9 CDJ86728.1 - 4.9e-98 329.1 0.6 5.8e-98 328.9 0.6 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn NDUFV3 PF15880.5 CDJ86729.1 - 2.1e-12 46.8 1.2 2.8e-12 46.4 1.2 1.2 1 0 0 1 1 1 1 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial Ig_3 PF13927.6 CDJ86731.1 - 3.3e-33 114.1 4.3 4.4e-09 36.8 0.0 7.1 8 0 0 8 8 8 4 Immunoglobulin domain I-set PF07679.16 CDJ86731.1 - 4.2e-32 110.1 0.0 5.5e-09 36.0 0.0 5.6 5 0 0 5 5 5 3 Immunoglobulin I-set domain Ig_2 PF13895.6 CDJ86731.1 - 2e-26 92.1 0.5 1.8e-06 28.2 0.0 6.9 6 1 0 6 6 6 3 Immunoglobulin domain ig PF00047.25 CDJ86731.1 - 4.2e-21 74.9 0.2 1e-05 25.6 0.0 6.2 6 0 0 6 6 6 4 Immunoglobulin domain fn3 PF00041.21 CDJ86731.1 - 8.1e-19 67.8 5.0 4.1e-06 27.1 0.4 5.0 4 1 0 4 4 4 4 Fibronectin type III domain V-set PF07686.17 CDJ86731.1 - 3e-10 40.2 7.6 0.24 11.6 0.1 7.5 6 3 1 8 8 8 4 Immunoglobulin V-set domain fn3_4 PF16794.5 CDJ86731.1 - 1.8e-05 24.6 0.2 0.0087 16.0 0.0 4.1 5 1 0 5 5 5 1 Fibronectin-III type domain Pur_ac_phosph_N PF16656.5 CDJ86731.1 - 9.8e-05 22.9 5.1 0.00025 21.5 0.2 3.7 4 0 0 4 4 3 1 Purple acid Phosphatase, N-terminal domain Ig_C17orf99 PF17736.1 CDJ86731.1 - 0.00055 19.9 0.1 0.21 11.7 0.0 3.2 3 0 0 3 3 3 1 C17orf99 Ig domain Ig_6 PF18452.1 CDJ86731.1 - 0.0015 18.0 0.0 3.6 7.2 0.0 3.9 4 0 0 4 4 4 1 Immunoglobulin domain Glyco_hydro_36C PF16874.5 CDJ86731.1 - 0.016 15.7 0.0 0.41 11.2 0.0 2.9 3 0 0 3 3 3 0 Glycosyl hydrolase family 36 C-terminal domain RRM_1 PF00076.22 CDJ86732.1 - 6.1e-07 29.2 0.0 5.1e-05 23.0 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Chromo_shadow PF01393.19 CDJ86734.1 - 1.1e-21 76.6 0.1 8.4e-20 70.6 0.0 2.2 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.24 CDJ86734.1 - 1.3e-19 69.8 3.6 4.4e-17 61.7 0.6 2.5 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 CDJ86734.1 - 8.3e-05 22.7 0.0 0.0032 17.6 0.0 2.2 2 0 0 2 2 2 1 Polycomb-like MTF2 factor 2 MerR_1 PF13411.6 CDJ86734.1 - 0.031 14.3 0.1 2 8.5 0.1 2.5 2 1 0 2 2 2 0 MerR HTH family regulatory protein DUF1918 PF08940.11 CDJ86734.1 - 0.092 12.4 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) JmjC PF02373.22 CDJ86735.1 - 8.9e-07 29.3 0.5 6.1e-05 23.4 0.5 2.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CDJ86735.1 - 5.2e-05 23.1 0.1 5.2e-05 23.1 0.1 3.0 2 1 0 2 2 2 1 Cupin-like domain JHD PF17811.1 CDJ86735.1 - 0.00015 22.3 0.3 0.00062 20.3 0.1 2.3 2 0 0 2 2 2 1 Jumonji helical domain Ilar_coat PF01787.16 CDJ86735.1 - 0.13 12.1 1.4 0.21 11.4 0.3 1.9 2 0 0 2 2 2 0 Ilarvirus coat protein Glyco_trans_1_4 PF13692.6 CDJ86736.1 - 9.4e-07 29.3 0.0 1.6e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CDJ86736.1 - 9e-06 26.2 0.0 2.8e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 CDJ86736.1 - 5e-05 23.4 1.3 0.00043 20.3 1.3 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 CDJ86736.1 - 0.0014 18.2 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CDJ86736.1 - 0.13 12.7 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 FGGY_C PF02782.16 CDJ86737.1 - 3.3e-07 30.2 0.3 3.9e-07 30.0 0.3 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Kelch_4 PF13418.6 CDJ86737.1 - 0.025 14.6 0.1 0.086 12.9 0.1 1.8 1 1 0 1 1 1 0 Galactose oxidase, central domain MreB_Mbl PF06723.13 CDJ86737.1 - 0.057 12.2 0.0 0.068 12.0 0.0 1.0 1 0 0 1 1 1 0 MreB/Mbl protein Kelch_1 PF01344.25 CDJ86737.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Kelch motif Sulfotransfer_3 PF13469.6 CDJ86739.1 - 3.7e-21 76.5 1.4 8.2e-10 39.4 0.0 2.0 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 CDJ86739.1 - 0.00067 19.2 0.1 0.0047 16.5 0.1 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 CDJ86739.1 - 0.0044 16.9 0.1 0.018 14.9 0.0 1.8 2 0 0 2 2 2 1 Sulfotransferase domain SAM_3 PF18016.1 CDJ86740.1 - 9.7e-24 83.0 0.2 1.7e-23 82.2 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 CDJ86740.1 - 0.00088 19.2 0.1 0.0015 18.5 0.1 1.3 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain DUF1202 PF06717.11 CDJ86741.1 - 0.021 14.3 0.8 0.024 14.1 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) Collagen PF01391.18 CDJ86742.1 - 6.5e-26 89.9 104.0 3.7e-05 23.4 10.0 4.2 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Collagen PF01391.18 CDJ86743.1 - 1.9e-26 91.6 103.0 3.1e-10 39.7 36.0 4.2 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Pribosyltran PF00156.27 CDJ86744.1 - 4.6e-20 71.7 0.2 6.3e-20 71.3 0.2 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 CDJ86744.1 - 0.0079 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase UPRTase PF14681.6 CDJ86744.1 - 0.011 15.1 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Nuc_sug_transp PF04142.15 CDJ86745.1 - 2.6e-106 355.3 16.5 3.1e-106 355.1 16.5 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 CDJ86745.1 - 5.9e-07 29.0 2.7 5.9e-07 29.0 2.7 2.0 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 CDJ86745.1 - 6.9e-06 26.3 26.0 4.8e-05 23.5 1.0 2.7 3 0 0 3 3 3 2 EamA-like transporter family CRT-like PF08627.10 CDJ86745.1 - 0.00028 20.0 0.8 0.00028 20.0 0.8 2.1 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 CDJ86745.1 - 0.00039 19.7 14.6 0.00092 18.5 13.4 2.0 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.6 CDJ86745.1 - 0.00074 19.2 0.4 0.00074 19.2 0.4 2.6 3 0 0 3 3 3 1 Putative multidrug resistance efflux transporter DUF4131 PF13567.6 CDJ86745.1 - 9.1 5.9 7.4 0.34 10.6 0.3 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Glyco_trans_A_1 PF09318.10 CDJ86746.1 - 0.019 14.7 1.5 0.021 14.5 1.5 1.0 1 0 0 1 1 1 0 Glycosyl transferase 1 domain A SH2 PF00017.24 CDJ86747.1 - 0.19 11.8 0.4 17 5.6 0.0 2.3 2 0 0 2 2 2 0 SH2 domain gag-asp_proteas PF13975.6 CDJ86748.1 - 1.3e-06 28.8 0.0 4.6e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ86748.1 - 2.1e-06 28.3 0.0 5.8e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ86748.1 - 0.00055 20.2 0.0 0.0021 18.4 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease eIF3g PF12353.8 CDJ86748.1 - 0.0069 16.8 1.9 0.0069 16.8 1.9 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor 3 subunit G DUF1539 PF07560.11 CDJ86748.1 - 0.039 14.1 0.3 0.17 11.9 0.1 2.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) PA26 PF04636.13 CDJ86748.1 - 0.043 12.7 6.4 0.015 14.3 1.4 2.0 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Asp_protease PF09668.10 CDJ86748.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Renin_r PF07850.14 CDJ86749.1 - 0.015 15.9 0.0 0.018 15.6 0.0 1.3 1 0 0 1 1 1 0 Renin receptor-like protein RT_RNaseH_2 PF17919.1 CDJ86750.1 - 1.1e-25 89.5 0.1 4.4e-25 87.6 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ86750.1 - 2.3e-25 88.9 0.1 1.1e-24 86.8 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ86750.1 - 1e-18 67.2 0.0 1.9e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 CDJ86750.1 - 4.4e-16 59.1 0.0 9.3e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 CDJ86750.1 - 0.0028 17.8 0.0 0.0077 16.4 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger gag-asp_proteas PF13975.6 CDJ86750.1 - 0.0034 17.9 0.0 0.0086 16.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ86750.1 - 0.011 16.4 0.0 0.024 15.3 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 CDJ86750.1 - 0.019 15.3 1.5 0.46 10.8 0.2 2.8 2 1 1 3 3 3 0 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ86750.1 - 0.024 14.5 0.0 0.061 13.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease EGF_CA PF07645.15 CDJ86751.1 - 4.2e-26 90.9 72.1 8.3e-09 35.5 4.4 5.4 5 0 0 5 5 5 4 Calcium-binding EGF domain EGF_3 PF12947.7 CDJ86751.1 - 1.5e-17 63.4 66.1 1.1e-07 31.9 7.5 5.5 5 0 0 5 5 5 4 EGF domain cEGF PF12662.7 CDJ86751.1 - 9.1e-10 38.3 42.7 6.9e-05 22.7 4.6 5.6 5 0 0 5 5 5 4 Complement Clr-like EGF-like EGF PF00008.27 CDJ86751.1 - 3.2e-08 33.7 65.4 0.0023 18.2 6.0 5.6 5 0 0 5 5 5 4 EGF-like domain EGF_MSP1_1 PF12946.7 CDJ86751.1 - 0.0018 18.3 5.4 0.0018 18.3 5.4 5.0 5 0 0 5 5 5 2 MSP1 EGF domain 1 EGF_Tenascin PF18720.1 CDJ86751.1 - 3.3 7.9 17.5 1.1 9.3 8.0 3.2 2 0 0 2 2 2 0 Tenascin EGF domain FXa_inhibition PF14670.6 CDJ86751.1 - 5 7.5 69.8 0.64 10.4 5.0 5.4 4 1 1 5 5 5 0 Coagulation Factor Xa inhibitory site hEGF PF12661.7 CDJ86751.1 - 5.9 7.7 48.7 0.38 11.5 4.6 5.9 5 0 0 5 5 5 0 Human growth factor-like EGF Phospholip_B PF04916.13 CDJ86753.1 - 4.4e-58 197.2 0.9 4.9e-58 197.0 0.9 1.0 1 0 0 1 1 1 1 Phospholipase B Peptidase_M13_N PF05649.13 CDJ86754.1 - 5.9e-15 55.8 0.0 6.6e-15 55.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 7tm_1 PF00001.21 CDJ86755.1 - 3.4e-05 23.3 0.4 3.4e-05 23.3 0.4 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ86755.1 - 0.0096 15.3 0.4 0.018 14.4 0.1 1.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4134 PF13572.6 CDJ86755.1 - 0.014 15.6 0.1 0.019 15.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) Gram_pos_anchor PF00746.21 CDJ86755.1 - 0.078 12.9 0.4 0.52 10.3 0.0 2.1 2 0 0 2 2 2 0 LPXTG cell wall anchor motif OPA3 PF07047.12 CDJ86755.1 - 0.16 11.7 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) DUF5305 PF17231.2 CDJ86755.1 - 0.28 10.6 0.0 0.36 10.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF756 PF05506.12 CDJ86756.1 - 0.12 13.4 0.0 0.23 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF756) HTH_48 PF17906.1 CDJ86757.1 - 0.034 14.2 0.0 0.98 9.6 0.0 2.3 2 0 0 2 2 2 0 HTH domain in Mos1 transposase Mtp PF03821.16 CDJ86758.1 - 0.37 10.3 5.3 0.65 9.6 0.6 2.0 1 1 0 2 2 2 0 Golgi 4-transmembrane spanning transporter Iso_dh PF00180.20 CDJ86759.1 - 4e-73 246.5 0.1 5.1e-73 246.2 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MAGE PF01454.19 CDJ86760.1 - 1.7e-09 37.7 0.0 1e-06 28.6 0.0 2.2 1 1 1 2 2 2 2 MAGE family PPR_2 PF13041.6 CDJ86761.1 - 1e-07 32.0 0.0 0.1 12.8 0.0 3.9 3 0 0 3 3 3 3 PPR repeat family PPR_3 PF13812.6 CDJ86761.1 - 5.5e-06 26.4 0.1 0.014 15.5 0.0 3.2 3 0 0 3 3 3 2 Pentatricopeptide repeat domain TAFH PF07531.14 CDJ86761.1 - 0.062 13.4 0.0 0.5 10.5 0.0 2.5 2 0 0 2 2 2 0 NHR1 homology to TAF RPM2 PF08579.11 CDJ86761.1 - 0.13 12.6 0.2 0.43 11.0 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) PPR PF01535.20 CDJ86761.1 - 0.21 11.9 4.0 43 4.7 0.0 4.6 5 0 0 5 5 5 0 PPR repeat ATP-gua_Ptrans PF00217.19 CDJ86762.1 - 2.7e-85 285.2 0.0 3.8e-85 284.7 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CDJ86762.1 - 5.8e-28 97.1 0.3 1.1e-27 96.2 0.0 1.6 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, N-terminal domain CRAL_TRIO PF00650.20 CDJ86763.1 - 5.6e-25 87.9 0.0 9.4e-25 87.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 CDJ86763.1 - 7.2e-07 29.8 1.4 0.011 16.3 0.1 2.3 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking Antistasin PF02822.14 CDJ86763.1 - 0.41 11.3 0.2 0.41 11.3 0.2 1.9 2 0 0 2 2 2 0 Antistasin family zf-C2H2 PF00096.26 CDJ86765.1 - 1.5e-27 94.5 45.9 4.8e-06 26.7 0.4 8.5 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ86765.1 - 1.1e-23 81.8 46.7 0.00066 20.3 0.2 8.5 8 0 0 8 8 8 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDJ86765.1 - 2.7e-18 65.5 36.6 1.6e-07 31.4 0.2 10.0 11 1 0 11 11 11 4 Zinc-finger double domain zf-met PF12874.7 CDJ86765.1 - 5.9e-17 61.4 32.9 0.0009 19.6 0.6 7.4 8 0 0 8 8 7 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDJ86765.1 - 4.7e-12 45.9 26.9 0.08 13.3 0.1 6.8 7 0 0 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CDJ86765.1 - 0.00028 21.2 34.6 0.52 10.7 1.4 7.2 5 2 2 7 7 7 4 C2H2 type zinc-finger (2 copies) zf-C2H2_8 PF15909.5 CDJ86765.1 - 0.00073 19.8 18.1 0.06 13.6 0.1 4.4 5 0 0 5 5 4 2 C2H2-type zinc ribbon zf-Di19 PF05605.12 CDJ86765.1 - 0.015 15.6 28.1 0.49 10.7 0.1 5.5 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 CDJ86765.1 - 0.058 14.1 12.4 1.1 10.0 0.0 5.1 4 1 1 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 CDJ86765.1 - 0.11 12.3 20.0 4.9 7.0 0.3 6.6 6 0 0 6 6 6 0 C2H2-type zinc-finger domain HTH_5 PF01022.20 CDJ86765.1 - 0.19 11.7 0.7 19 5.2 0.1 2.6 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family zf-C2H2_11 PF16622.5 CDJ86765.1 - 0.2 11.4 0.0 0.2 11.4 0.0 6.5 7 0 0 7 7 7 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 CDJ86765.1 - 0.54 10.3 43.7 0.32 11.0 0.8 6.9 8 0 0 8 8 7 0 C2H2-type zinc finger zf-MYST PF17772.1 CDJ86765.1 - 1.4 8.6 8.1 3.9 7.2 0.6 3.5 4 0 0 4 4 4 0 MYST family zinc finger domain zf-C2HE PF16278.5 CDJ86765.1 - 6.9 7.2 25.3 16 6.0 1.7 5.7 5 1 0 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger ubiquitin PF00240.23 CDJ86766.1 - 5.4e-13 48.5 0.3 8.5e-13 47.9 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family STI1 PF17830.1 CDJ86766.1 - 3.2e-09 36.6 55.1 0.00011 22.1 7.1 5.5 3 2 2 5 5 5 4 STI1 domain UBA PF00627.31 CDJ86766.1 - 8.9e-08 31.9 5.8 1.1e-07 31.6 0.6 3.6 3 0 0 3 3 3 1 UBA/TS-N domain Rad60-SLD PF11976.8 CDJ86766.1 - 0.00023 20.9 0.2 0.00039 20.2 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CDJ86766.1 - 0.0021 18.6 0.1 0.008 16.7 0.1 2.0 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain XPC-binding PF09280.11 CDJ86766.1 - 0.0088 15.8 16.3 0.0088 15.8 16.3 6.1 3 2 2 5 5 5 1 XPC-binding domain Rad60-SLD_2 PF13881.6 CDJ86766.1 - 0.033 14.3 0.2 0.13 12.4 0.2 1.9 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like LPD22 PF18834.1 CDJ86766.1 - 0.21 11.8 2.5 6.6 7.0 0.1 3.6 2 2 0 2 2 2 0 Large polyvalent protein associated domain 22 DUF1858 PF08984.11 CDJ86766.1 - 0.99 9.6 3.0 2.6 8.3 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1858) Thioredoxin PF00085.20 CDJ86767.1 - 4.8e-63 209.6 1.1 4e-32 110.3 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 CDJ86767.1 - 4.5e-31 108.2 6.3 1.6e-24 86.8 5.5 3.8 2 1 2 4 4 4 4 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CDJ86767.1 - 4.7e-09 36.5 0.0 0.014 15.7 0.0 3.7 2 2 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 CDJ86767.1 - 1.9e-08 34.7 1.8 0.0011 19.4 0.1 3.4 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CDJ86767.1 - 6.4e-08 32.7 0.1 0.0029 17.7 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 CDJ86767.1 - 1e-07 31.9 0.2 0.018 15.0 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 CDJ86767.1 - 2e-06 27.6 2.8 0.034 13.8 0.0 3.9 4 0 0 4 4 4 2 Redoxin OST3_OST6 PF04756.13 CDJ86767.1 - 4.8e-06 26.1 0.0 0.0098 15.3 0.0 2.5 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family TraF PF13728.6 CDJ86767.1 - 1e-05 25.5 0.0 0.0088 15.9 0.0 2.5 2 1 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 CDJ86767.1 - 0.035 13.9 0.2 3.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin ExbD PF02472.16 CDJ86767.1 - 0.044 13.9 0.2 0.75 10.0 0.1 2.2 1 1 1 2 2 2 0 Biopolymer transport protein ExbD/TolR Thioredoxin_4 PF13462.6 CDJ86767.1 - 0.063 13.4 1.4 1.2 9.3 0.1 3.1 3 1 1 4 4 4 0 Thioredoxin zf-RING_2 PF13639.6 CDJ86768.1 - 1.2e-12 48.0 4.9 1.8e-12 47.3 4.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ86768.1 - 3.3e-10 39.6 3.6 5.3e-10 39.0 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDJ86768.1 - 1e-09 37.9 2.0 2.1e-09 37.0 2.0 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 CDJ86768.1 - 9.7e-09 35.4 2.8 2e-08 34.4 2.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDJ86768.1 - 3.9e-08 33.0 2.6 6.3e-08 32.4 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ86768.1 - 1.7e-05 24.7 2.6 3.2e-05 23.8 2.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDJ86768.1 - 0.00037 20.5 2.7 0.00081 19.4 2.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CDJ86768.1 - 0.0014 18.4 3.0 0.0027 17.5 3.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CDJ86768.1 - 0.0024 17.7 1.8 0.004 17.0 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ZNRF_3_ecto PF18212.1 CDJ86768.1 - 0.023 14.7 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 ZNRF-3 Ectodomain zf-ANAPC11 PF12861.7 CDJ86768.1 - 0.056 13.5 2.5 0.23 11.5 2.5 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 CDJ86768.1 - 0.11 12.4 2.5 0.2 11.6 2.5 1.5 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.6 CDJ86768.1 - 0.2 11.8 1.6 0.3 11.3 0.4 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.8 CDJ86768.1 - 0.25 11.6 3.1 0.73 10.1 3.1 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 CDJ86768.1 - 0.38 10.4 2.0 0.69 9.6 2.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-H2C2_2 PF13465.6 CDJ86769.1 - 0.16 12.4 71.9 0.06 13.8 0.9 11.6 14 0 0 14 14 14 0 Zinc-finger double domain zf-Di19 PF05605.12 CDJ86769.1 - 0.29 11.5 79.9 0.029 14.6 9.7 8.7 7 2 2 9 9 9 0 Drought induced 19 protein (Di19), zinc-binding PHZA_PHZB PF03284.13 CDJ86769.1 - 0.5 10.0 8.7 2.6 7.6 0.4 3.9 4 0 0 4 4 4 0 Phenazine biosynthesis protein A/B 7tm_1 PF00001.21 CDJ86770.1 - 6.5e-09 35.5 1.7 8.1e-09 35.2 1.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PRIMA1 PF16101.5 CDJ86770.1 - 1.7e-05 24.8 1.9 0.0001 22.3 0.0 2.8 2 1 1 3 3 3 1 Proline-rich membrane anchor 1 FtsX PF02687.21 CDJ86770.1 - 0.22 12.0 2.8 2.8 8.5 1.7 2.2 2 0 0 2 2 2 0 FtsX-like permease family Orf78 PF06024.12 CDJ86770.1 - 2.3 8.6 4.2 20 5.6 3.1 2.2 1 1 1 2 2 2 0 Orf78 (ac78) Tubulin-binding PF00418.19 CDJ86771.1 - 4.8e-48 160.8 21.8 1.8e-15 56.6 0.2 5.9 6 0 0 6 6 6 5 Tau and MAP protein, tubulin-binding repeat DUF5310 PF17237.2 CDJ86772.1 - 0.44 10.5 3.7 2 8.3 3.7 2.2 1 0 0 1 1 1 0 Family of unknown function (DUF5310) Flp1_like PF16982.5 CDJ86772.1 - 0.86 9.1 0.0 0.86 9.1 0.0 3.1 4 0 0 4 4 4 0 Putative Flagellin, Flp1-like, domain Kunitz_BPTI PF00014.23 CDJ86773.1 - 2.1e-79 261.6 81.9 2e-18 66.3 14.8 6.9 6 0 0 6 6 6 5 Kunitz/Bovine pancreatic trypsin inhibitor domain Lustrin_cystein PF14625.6 CDJ86773.1 - 3.3e-26 91.4 167.8 2.2e-08 34.3 8.5 12.3 12 1 0 12 12 12 8 Lustrin, cysteine-rich repeated domain EB PF01683.18 CDJ86773.1 - 8.8e-08 32.3 8.9 8.8e-08 32.3 8.9 11.2 10 4 1 11 11 11 2 EB module Pkinase_Tyr PF07714.17 CDJ86774.1 - 1.1e-23 83.8 0.1 1.8e-23 83.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ86774.1 - 1.5e-23 83.5 0.0 2.9e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain OSR1_C PF12202.8 CDJ86774.1 - 0.1 12.9 0.0 0.36 11.1 0.0 2.0 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C-terminal domain Ferrochelatase PF00762.19 CDJ86775.1 - 7.8e-14 51.5 0.0 1.2e-13 50.8 0.0 1.5 1 1 0 1 1 1 1 Ferrochelatase Carm_PH PF17888.1 CDJ86776.1 - 3.1e-17 62.7 0.1 6.5e-17 61.7 0.1 1.5 1 0 0 1 1 1 1 Carmil pleckstrin homology domain LRR_1 PF00560.33 CDJ86776.1 - 0.012 16.0 9.9 1.9 9.3 0.2 7.2 8 0 0 8 8 8 0 Leucine Rich Repeat LRR_4 PF12799.7 CDJ86776.1 - 0.028 14.8 17.7 3.3 8.2 0.2 5.5 3 2 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CDJ86776.1 - 6.2 7.1 32.4 11 6.3 0.1 8.5 10 0 0 10 10 10 0 Leucine Rich repeat DLIC PF05783.11 CDJ86777.1 - 1.4e-71 241.8 0.1 5.5e-71 239.8 0.1 1.8 1 1 0 1 1 1 1 Dynein light intermediate chain (DLIC) RsgA_GTPase PF03193.16 CDJ86777.1 - 7e-05 22.8 1.7 0.059 13.3 0.0 2.6 3 0 0 3 3 3 2 RsgA GTPase Ras PF00071.22 CDJ86777.1 - 0.00019 21.1 0.0 0.35 10.4 0.0 2.6 2 1 0 2 2 2 2 Ras family Roc PF08477.13 CDJ86777.1 - 0.0025 18.0 0.0 0.0078 16.4 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 CDJ86777.1 - 0.01 15.6 0.4 27 4.5 0.0 3.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 CDJ86777.1 - 0.065 12.7 0.1 2.4 7.6 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family ABC_tran PF00005.27 CDJ86777.1 - 0.07 13.6 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 CDJ86777.1 - 0.1 12.4 0.7 0.24 11.1 0.7 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CDJ86777.1 - 0.14 12.6 1.6 0.81 10.1 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain HSBP1 PF06825.12 CDJ86778.1 - 1.6e-23 82.3 7.5 2.1e-23 81.9 7.5 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 EspB PF05802.11 CDJ86778.1 - 0.0042 17.1 0.9 0.0052 16.8 0.9 1.1 1 0 0 1 1 1 1 Enterobacterial EspB protein Prefoldin_3 PF13758.6 CDJ86778.1 - 0.0043 17.1 0.1 0.0047 16.9 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit FliD_C PF07195.12 CDJ86778.1 - 0.0094 15.4 0.5 0.0098 15.3 0.5 1.2 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus Cullin_Nedd8 PF10557.9 CDJ86778.1 - 0.016 15.2 0.4 0.029 14.4 0.4 1.5 1 1 0 1 1 1 0 Cullin protein neddylation domain DUF3802 PF12290.8 CDJ86778.1 - 0.027 15.0 1.3 0.03 14.8 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) Matrilin_ccoil PF10393.9 CDJ86778.1 - 0.037 13.9 0.1 0.069 13.0 0.1 1.6 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin TssO PF17561.2 CDJ86778.1 - 0.039 14.1 1.8 0.045 13.8 1.8 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO BLOC1_2 PF10046.9 CDJ86778.1 - 0.041 14.2 0.3 0.061 13.6 0.3 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PhoU PF01895.19 CDJ86778.1 - 0.047 14.1 0.6 0.058 13.9 0.6 1.2 1 0 0 1 1 1 0 PhoU domain Allexi_40kDa PF05549.11 CDJ86778.1 - 0.057 12.9 0.3 0.056 12.9 0.3 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF2200 PF09966.9 CDJ86778.1 - 0.069 13.3 0.1 0.083 13.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) DUF948 PF06103.11 CDJ86778.1 - 0.12 12.6 0.3 0.21 11.8 0.3 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) BST2 PF16716.5 CDJ86778.1 - 0.13 12.8 1.0 0.37 11.4 1.0 1.7 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 7tm_1 PF00001.21 CDJ86779.1 - 3.7e-14 52.7 20.5 3.7e-14 52.7 20.5 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF148 PF02520.17 CDJ86780.1 - 0.21 11.7 0.0 0.25 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF148 DUF148 PF02520.17 CDJ86781.1 - 7.5e-18 64.6 6.7 1.2e-17 63.9 6.7 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF148 DUF4142 PF13628.6 CDJ86781.1 - 0.0053 17.0 3.3 0.0086 16.3 3.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4142) DUF241 PF03087.14 CDJ86781.1 - 0.0063 16.4 2.3 0.0083 16.0 2.3 1.2 1 0 0 1 1 1 1 Arabidopsis protein of unknown function NB-ARC PF00931.22 CDJ86781.1 - 0.0066 15.7 0.6 0.0099 15.1 0.6 1.3 1 0 0 1 1 1 1 NB-ARC domain T4_Rnl2_C PF18043.1 CDJ86781.1 - 0.012 15.8 10.2 0.27 11.4 0.4 2.7 3 0 0 3 3 3 0 T4 RNA ligase 2 C-terminal KapB PF08810.10 CDJ86781.1 - 0.053 13.7 2.0 0.093 12.9 2.0 1.5 1 0 0 1 1 1 0 Kinase associated protein B SUKH-3 PF14433.6 CDJ86781.1 - 0.14 12.6 0.1 1.1 9.7 0.0 2.0 1 1 1 2 2 2 0 SUKH-3 immunity protein OmpH PF03938.14 CDJ86781.1 - 1.5 9.2 10.7 2.8 8.3 10.7 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FapA PF03961.13 CDJ86781.1 - 1.9 7.0 6.5 1.1 7.8 0.1 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF148 PF02520.17 CDJ86782.1 - 5e-23 81.3 4.9 7.2e-23 80.8 4.9 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF148 DUF148 PF02520.17 CDJ86783.1 - 6e-20 71.4 0.3 7e-20 71.2 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 DUF148 PF02520.17 CDJ86785.1 - 6.1e-07 29.5 0.2 7.8e-07 29.2 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 DUF148 PF02520.17 CDJ86786.1 - 1e-84 279.8 27.5 2.8e-29 101.4 4.7 3.0 3 0 0 3 3 3 3 Domain of unknown function DUF148 T2SSF PF00482.23 CDJ86786.1 - 1.7e-05 24.8 3.6 3.2 7.7 0.0 3.8 4 0 0 4 4 3 0 Type II secretion system (T2SS), protein F HEAT PF02985.22 CDJ86786.1 - 5.2e-05 23.1 0.0 0.8 10.1 0.0 4.0 3 0 0 3 3 3 1 HEAT repeat DASH_Dam1 PF08653.10 CDJ86786.1 - 0.00034 20.3 8.4 1 9.2 0.2 3.5 3 0 0 3 3 3 2 DASH complex subunit Dam1 RuvX PF03652.15 CDJ86786.1 - 0.00044 20.6 9.5 0.62 10.5 0.2 3.1 3 0 0 3 3 3 1 Holliday junction resolvase Nmad5 PF18757.1 CDJ86786.1 - 0.00046 20.5 6.4 1.4 9.1 0.2 3.2 3 0 0 3 3 3 2 Nucleotide modification associated domain 5 SF-assemblin PF06705.11 CDJ86786.1 - 0.00073 18.9 24.4 0.11 11.8 3.0 3.1 3 0 0 3 3 3 3 SF-assemblin/beta giardin DUF4142 PF13628.6 CDJ86786.1 - 0.00091 19.5 1.1 2.9 8.1 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4142) DUF713 PF05218.14 CDJ86786.1 - 0.001 18.8 11.6 0.37 10.5 0.4 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF713) HisKA_3 PF07730.13 CDJ86786.1 - 0.0024 18.3 1.4 8 7.1 0.0 3.7 3 0 0 3 3 3 0 Histidine kinase DUF2130 PF09903.9 CDJ86786.1 - 0.0029 16.9 14.2 0.55 9.5 0.9 3.1 3 0 0 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2130) Pro-rich PF15240.6 CDJ86786.1 - 0.005 17.1 60.9 0.26 11.5 42.3 3.5 3 0 0 3 3 3 2 Proline-rich TetR_C_4 PF08359.11 CDJ86786.1 - 0.0085 16.2 7.9 5.4 7.2 0.2 3.2 3 0 0 3 3 3 0 YsiA-like protein, C-terminal region NIT PF08376.10 CDJ86786.1 - 0.01 16.3 15.7 0.95 9.9 1.0 3.1 3 0 0 3 3 3 0 Nitrate and nitrite sensing Na_Ca_ex_C PF16494.5 CDJ86786.1 - 0.012 16.0 9.3 3.6 8.1 0.4 3.3 3 0 0 3 3 3 0 C-terminal extension of sodium/calcium exchanger domain TEX12 PF15219.6 CDJ86786.1 - 0.02 15.2 6.1 5.6 7.4 0.1 3.4 3 0 0 3 3 3 0 Testis-expressed 12 COG2 PF06148.11 CDJ86786.1 - 0.021 14.9 10.7 2.3 8.3 0.6 3.3 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 CLZ PF16526.5 CDJ86786.1 - 0.021 15.2 7.9 3.5 8.0 0.3 3.5 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MAD PF05557.13 CDJ86786.1 - 0.026 12.9 18.1 0.6 8.4 1.2 3.1 3 0 0 3 3 3 0 Mitotic checkpoint protein SKA2 PF16740.5 CDJ86786.1 - 0.027 14.3 12.6 1.5 8.6 0.2 3.8 5 0 0 5 5 3 0 Spindle and kinetochore-associated protein 2 GLE1 PF07817.13 CDJ86786.1 - 0.032 13.4 1.4 11 5.1 0.1 3.1 3 0 0 3 3 3 0 GLE1-like protein Matrilin_ccoil PF10393.9 CDJ86786.1 - 0.039 13.8 0.8 73 3.3 0.0 3.8 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Pup PF05639.11 CDJ86786.1 - 0.043 14.7 16.0 2.8 8.9 0.5 3.6 3 0 0 3 3 3 0 Pup-like protein Apolipoprotein PF01442.18 CDJ86786.1 - 0.045 13.6 19.4 1.5 8.7 1.8 3.2 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain Pex24p PF06398.11 CDJ86786.1 - 0.056 12.4 3.0 0.65 8.9 0.1 2.8 3 0 0 3 3 3 0 Integral peroxisomal membrane peroxin Imm30 PF15565.6 CDJ86786.1 - 0.058 13.5 9.7 7.2 6.8 0.2 3.3 3 0 0 3 3 3 0 Immunity protein 30 MotCF PF09158.10 CDJ86786.1 - 0.061 13.4 1.1 46 4.2 0.0 3.2 3 0 0 3 3 3 0 Bacteriophage T4 MotA, C-terminal Xpo1 PF08389.12 CDJ86786.1 - 0.067 13.2 9.1 2.8 8.0 0.3 3.3 3 0 0 3 3 3 0 Exportin 1-like protein DegS PF05384.11 CDJ86786.1 - 0.09 12.3 28.4 0.53 9.8 2.4 4.5 3 3 2 5 5 5 0 Sensor protein DegS Prok-E2_B PF14461.6 CDJ86786.1 - 0.096 12.4 8.7 10 5.8 0.3 3.5 3 0 0 3 3 3 0 Prokaryotic E2 family B Syntaxin_2 PF14523.6 CDJ86786.1 - 0.11 12.9 16.3 2.7 8.4 1.2 3.3 3 0 0 3 3 3 0 Syntaxin-like protein PSII_Pbs27 PF13326.6 CDJ86786.1 - 0.13 12.6 10.7 10 6.4 0.1 4.8 3 3 3 6 6 6 0 Photosystem II Pbs27 sCache_2 PF17200.4 CDJ86786.1 - 0.13 12.1 3.1 35 4.2 0.1 3.3 3 0 0 3 3 3 0 Single Cache domain 2 MnmE_helical PF12631.7 CDJ86786.1 - 0.15 12.2 11.0 7.6 6.6 0.5 3.3 3 0 0 3 3 3 0 MnmE helical domain Prominin PF05478.11 CDJ86786.1 - 0.22 9.5 16.0 1.2 7.0 1.2 3.1 3 0 0 3 3 3 0 Prominin Metal_resist PF13801.6 CDJ86786.1 - 0.22 11.7 5.5 23 5.2 0.0 5.9 6 1 1 7 7 4 0 Heavy-metal resistance TcdB_N PF12918.7 CDJ86786.1 - 0.24 11.7 11.7 4.2 7.7 0.0 4.4 5 0 0 5 5 3 0 TcdB toxin N-terminal helical domain RsbRD_N PF14361.6 CDJ86786.1 - 0.29 11.8 15.8 1.5 9.5 0.3 3.3 3 0 0 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain ENTH PF01417.20 CDJ86786.1 - 0.33 11.0 7.0 17 5.5 0.2 3.2 3 0 0 3 3 3 0 ENTH domain PTPA PF03095.15 CDJ86786.1 - 0.41 10.0 6.8 13 5.1 0.2 3.0 3 0 0 3 3 3 0 Phosphotyrosyl phosphate activator (PTPA) protein RNase_J_C PF17770.1 CDJ86786.1 - 0.48 11.5 7.4 31 5.7 0.2 3.9 3 0 0 3 3 3 0 Ribonuclease J C-terminal domain DUF1664 PF07889.12 CDJ86786.1 - 0.48 10.5 13.2 7.9 6.5 0.8 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Med11 PF10280.9 CDJ86786.1 - 0.49 10.9 9.3 13 6.3 0.5 3.4 3 0 0 3 3 3 0 Mediator complex protein Baculo_PEP_C PF04513.12 CDJ86786.1 - 0.61 10.1 17.2 3.1 7.8 1.4 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TipAS PF07739.13 CDJ86786.1 - 0.79 10.3 10.4 9.9 6.7 0.2 3.2 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain Cbl_N PF02262.16 CDJ86786.1 - 1 9.4 4.7 25 4.9 0.2 3.9 3 3 0 3 3 3 0 CBL proto-oncogene N-terminal domain 1 Exonuc_VII_L PF02601.15 CDJ86786.1 - 1.1 8.7 12.8 5 6.6 0.4 3.0 3 0 0 3 3 3 0 Exonuclease VII, large subunit AvrM-A PF18241.1 CDJ86786.1 - 1.2 9.6 5.0 25 5.2 0.1 3.3 3 0 0 3 3 3 0 Flax-rust effector AvrM-A CREPT PF16566.5 CDJ86786.1 - 1.2 9.3 12.3 8.4 6.6 0.5 3.3 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour KapB PF08810.10 CDJ86786.1 - 1.2 9.3 7.8 34 4.7 0.2 3.2 3 0 0 3 3 3 0 Kinase associated protein B Laminin_II PF06009.12 CDJ86786.1 - 1.3 9.1 16.5 7.7 6.5 1.4 3.3 3 0 0 3 3 3 0 Laminin Domain II ING PF12998.7 CDJ86786.1 - 1.9 9.1 14.2 13 6.5 1.0 3.4 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Peptidase_S64 PF08192.11 CDJ86786.1 - 2.3 6.6 14.7 4.2 5.7 0.8 3.0 3 0 0 3 3 3 0 Peptidase family S64 Phasin PF05597.11 CDJ86786.1 - 3.6 7.6 8.9 12 5.9 0.4 3.1 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Nic96 PF04097.14 CDJ86786.1 - 3.8 5.8 8.7 14 4.0 0.3 3.0 3 0 0 3 3 3 0 Nup93/Nic96 YtxH PF12732.7 CDJ86786.1 - 4.4 7.9 9.9 55 4.4 0.6 3.6 3 0 0 3 3 3 0 YtxH-like protein DUF883 PF05957.13 CDJ86786.1 - 4.4 8.0 5.9 31 5.3 0.1 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) HU-CCDC81_bac_2 PF18175.1 CDJ86786.1 - 5.6 6.9 8.0 15 5.5 0.3 3.5 3 1 0 3 3 3 0 CCDC81-like prokaryotic HU domain 2 DUF5446 PF17522.2 CDJ86786.1 - 6 7.1 22.1 1.3 9.2 1.5 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5446) DUF4061 PF13270.6 CDJ86786.1 - 7.9 6.9 14.4 27 5.1 0.4 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4061) APP_E2 PF12925.7 CDJ86786.1 - 9.9 5.8 16.4 5.1 6.8 0.7 3.1 3 0 0 3 3 3 0 E2 domain of amyloid precursor protein DUF148 PF02520.17 CDJ86787.1 - 5.2e-15 55.5 7.1 6.4e-15 55.2 7.1 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 MukF_M PF17192.4 CDJ86787.1 - 0.00079 19.2 1.1 0.0011 18.7 1.1 1.2 1 0 0 1 1 1 1 MukF middle domain RRF PF01765.19 CDJ86787.1 - 0.24 11.3 1.5 0.35 10.8 1.5 1.2 1 0 0 1 1 1 0 Ribosome recycling factor DUF4148 PF13663.6 CDJ86788.1 - 0.026 14.7 0.0 0.034 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) DUF148 PF02520.17 CDJ86789.1 - 4.2e-07 30.0 1.5 5.6e-07 29.6 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF148 Metal_resist PF13801.6 CDJ86789.1 - 0.17 12.1 0.0 0.39 10.9 0.0 1.5 2 0 0 2 2 2 0 Heavy-metal resistance Asp PF00026.23 CDJ86791.1 - 2.2e-66 224.5 0.0 2.5e-66 224.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ86791.1 - 1.1e-08 35.6 0.4 3e-08 34.1 0.3 1.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ86791.1 - 0.0035 17.1 0.0 0.0065 16.3 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CDJ86791.1 - 0.19 12.4 0.0 29 5.4 0.0 3.1 3 0 0 3 3 3 0 Aspartyl protease UDPGT PF00201.18 CDJ86792.1 - 3.8e-45 154.6 0.0 4.9e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ86792.1 - 6.1e-07 29.6 0.0 1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Epimerase_2 PF02350.19 CDJ86792.1 - 0.18 10.7 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase UDPGT PF00201.18 CDJ86793.1 - 7.1e-53 180.1 0.0 8.3e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ86793.1 - 6.9e-15 55.4 0.0 1.1e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 CDJ86793.1 - 4.7e-05 22.8 0.0 0.0001 21.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 1 Glyco_trans_1_4 PF13692.6 CDJ86793.1 - 0.064 13.7 0.0 0.35 11.3 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferases group 1 PBS_linker_poly PF00427.21 CDJ86793.1 - 0.1 12.6 0.0 0.37 10.8 0.0 1.9 2 0 0 2 2 2 0 Phycobilisome Linker polypeptide zf-nanos PF05741.13 CDJ86794.1 - 0.00041 20.5 4.0 0.0031 17.7 4.0 2.2 1 1 0 1 1 1 1 Nanos RNA binding domain 7TM_GPCR_Srx PF10328.9 CDJ86796.1 - 2.2e-11 43.9 7.8 2.3e-11 43.8 7.8 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx PsbT PF01405.17 CDJ86796.1 - 0.1 12.4 0.6 0.24 11.2 0.6 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre T protein Kelch_4 PF13418.6 CDJ86797.1 - 5.5e-07 29.5 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_2 PF07646.15 CDJ86797.1 - 0.00093 19.1 2.1 0.044 13.8 0.5 3.2 3 1 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 CDJ86797.1 - 0.0011 19.2 0.0 0.0098 16.2 0.0 2.3 2 0 0 2 2 2 1 Galactose oxidase, central domain Myb_DNA-bind_5 PF13873.6 CDJ86797.1 - 0.012 15.7 0.1 0.03 14.4 0.1 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Kelch_1 PF01344.25 CDJ86797.1 - 0.035 13.7 0.2 0.11 12.1 0.1 2.0 2 0 0 2 2 2 0 Kelch motif Kelch_5 PF13854.6 CDJ86797.1 - 0.065 13.2 0.0 0.77 9.8 0.0 2.5 2 0 0 2 2 2 0 Kelch motif DDE_Tnp_4 PF13359.6 CDJ86798.1 - 2.1e-11 43.7 0.6 3.4e-11 43.1 0.6 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 CDJ86798.1 - 0.00023 20.9 0.1 0.00034 20.3 0.1 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 CDJ86798.1 - 0.0018 18.0 0.2 0.0031 17.2 0.2 1.3 1 0 0 1 1 1 1 Transposase DDE domain TPR_2 PF07719.17 CDJ86799.1 - 4.5e-14 51.3 0.0 0.00054 19.9 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ86799.1 - 1.6e-11 43.5 0.0 0.0015 18.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat LEM PF03020.15 CDJ86799.1 - 1.1e-10 40.9 0.0 2.6e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 LEM domain TPR_8 PF13181.6 CDJ86799.1 - 1.5e-09 37.3 0.0 0.056 13.7 0.0 4.2 4 0 0 4 4 3 3 Tetratricopeptide repeat Ank_5 PF13857.6 CDJ86799.1 - 1.7e-09 37.7 0.4 5.3e-09 36.2 0.4 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) TPR_14 PF13428.6 CDJ86799.1 - 2.2e-07 31.1 0.4 0.95 10.5 0.0 4.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ86799.1 - 1.5e-06 28.7 0.3 1.6e-05 25.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Ank_4 PF13637.6 CDJ86799.1 - 2.2e-06 28.1 0.4 0.0016 18.9 0.0 2.9 2 1 1 3 3 2 2 Ankyrin repeats (many copies) TPR_9 PF13371.6 CDJ86799.1 - 2.7e-06 27.4 0.3 0.00025 21.2 0.1 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat Ank PF00023.30 CDJ86799.1 - 2.9e-06 27.5 2.9 4.2e-05 23.8 0.6 3.5 4 0 0 4 4 3 1 Ankyrin repeat TPR_11 PF13414.6 CDJ86799.1 - 6.2e-06 25.8 0.0 0.00016 21.3 0.0 2.4 2 0 0 2 2 2 1 TPR repeat Ank_2 PF12796.7 CDJ86799.1 - 6.8e-06 26.6 1.0 5.1e-05 23.8 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDJ86799.1 - 5.7e-05 23.2 1.6 0.00077 19.7 0.2 3.2 3 0 0 3 3 3 1 Ankyrin repeat TPR_19 PF14559.6 CDJ86799.1 - 9.6e-05 22.8 1.8 0.25 11.9 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ86799.1 - 0.00022 21.4 0.3 0.49 10.7 0.1 2.8 1 1 0 2 2 2 2 Tetratricopeptide repeat Gag_p6 PF08705.11 CDJ86799.1 - 0.014 15.6 5.8 0.018 15.2 3.4 2.5 2 1 0 2 2 2 0 Gag protein p6 TPR_17 PF13431.6 CDJ86799.1 - 0.18 12.3 0.4 8 7.1 0.0 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat CDPS PF16715.5 CDJ86799.1 - 0.2 11.3 0.0 0.2 11.3 0.0 2.3 2 0 0 2 2 2 0 Cyclodipeptide synthase Glyco_transf_18 PF15024.6 CDJ86800.1 - 3.7e-179 596.9 0.0 4.2e-179 596.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 18 RhoGAP PF00620.27 CDJ86801.1 - 5e-25 88.1 0.1 1.4e-24 86.6 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain MyTH4 PF00784.17 CDJ86801.1 - 1.9e-17 63.7 0.3 4.6e-17 62.5 0.3 1.6 1 0 0 1 1 1 1 MyTH4 domain WW PF00397.26 CDJ86801.1 - 1e-07 31.9 4.0 5e-05 23.3 3.3 2.5 2 0 0 2 2 2 2 WW domain UPF0004 PF00919.20 CDJ86802.1 - 1.9e-18 66.3 0.0 5.2e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 CDJ86802.1 - 4.1e-16 59.8 0.0 7.9e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily ARL17 PF15840.5 CDJ86802.1 - 0.0078 16.6 0.0 0.021 15.2 0.0 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor-like protein 17 DUF4995 PF16386.5 CDJ86802.1 - 0.028 14.4 0.0 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function PLDc_N PF13396.6 CDJ86802.1 - 0.04 13.9 0.2 0.08 12.9 0.2 1.5 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal NUDIX PF00293.28 CDJ86803.1 - 5.4e-19 68.5 1.6 6.1e-19 68.4 1.6 1.1 1 0 0 1 1 1 1 NUDIX domain PEPCK_GTP PF00821.18 CDJ86804.1 - 4.8e-162 538.8 0.2 5.8e-162 538.5 0.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 CDJ86804.1 - 2e-95 318.5 0.0 6.7e-95 316.8 0.0 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate carboxykinase N-terminal domain BAH PF01426.18 CDJ86805.1 - 1.5e-20 73.2 0.0 4.1e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 CDJ86805.1 - 3.8e-08 33.1 9.3 3.8e-08 33.1 9.3 2.2 2 0 0 2 2 2 1 PHD-finger SET PF00856.28 CDJ86805.1 - 4.4e-06 27.2 0.0 4.4e-06 27.2 0.0 3.4 2 2 1 3 3 3 1 SET domain PHD_2 PF13831.6 CDJ86805.1 - 0.019 14.5 2.6 0.051 13.1 2.6 1.7 1 0 0 1 1 1 0 PHD-finger C1_2 PF03107.16 CDJ86805.1 - 0.48 10.8 5.5 1.1 9.6 1.9 2.9 2 0 0 2 2 2 0 C1 domain gag-asp_proteas PF13975.6 CDJ86806.1 - 9.3e-08 32.5 0.0 2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ86806.1 - 2.9e-06 27.8 0.0 5.9e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 CDJ86806.1 - 7.4e-05 22.4 0.0 0.00016 21.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PNMA PF14893.6 CDJ86806.1 - 0.00028 20.4 0.1 0.00057 19.4 0.1 1.6 1 1 0 1 1 1 1 PNMA RVP PF00077.20 CDJ86806.1 - 0.00096 19.4 0.0 0.0024 18.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ86806.1 - 0.049 13.4 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 CDJ86807.1 - 6.2e-34 116.0 0.0 1.1e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ86807.1 - 8.5e-32 109.6 0.0 1.6e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ86807.1 - 4.5e-15 55.5 0.0 9.4e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDJ86807.1 - 6.6e-05 23.1 0.0 0.00023 21.4 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 CDJ86807.1 - 0.00054 20.1 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger L51_S25_CI-B8 PF05047.16 CDJ86807.1 - 0.037 14.0 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain gag_pre-integrs PF13976.6 CDJ86807.1 - 0.076 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 GAG-pre-integrase domain RVT_1 PF00078.27 CDJ86808.1 - 4.2e-08 33.0 0.0 6.2e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pellino PF04710.14 CDJ86809.1 - 1.3e-177 590.6 0.0 1.6e-177 590.3 0.0 1.0 1 0 0 1 1 1 1 Pellino zf-Di19 PF05605.12 CDJ86809.1 - 0.0038 17.5 1.9 1.4 9.2 0.1 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-RING_UBOX PF13445.6 CDJ86809.1 - 0.06 13.4 1.6 1.6 8.8 0.1 2.9 1 1 1 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.6 CDJ86809.1 - 0.083 12.8 6.5 8.3 6.4 0.2 3.3 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CDJ86809.1 - 1.9 8.4 6.4 14 5.7 1.3 3.5 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ86809.1 - 3.1 7.8 6.5 0.57 10.2 0.4 2.7 3 0 0 3 3 3 0 zinc-RING finger domain DUF4930 PF16284.5 CDJ86810.1 - 0.11 12.4 0.3 0.23 11.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4930) SH3_4 PF06347.13 CDJ86813.1 - 0.0044 16.8 0.3 48 3.9 0.0 6.0 5 3 2 8 8 8 1 Bacterial SH3 domain Foie-gras_1 PF11817.8 CDJ86814.1 - 0.094 12.3 0.0 0.1 12.1 0.0 1.0 1 0 0 1 1 1 0 Foie gras liver health family 1 MIP-T3_C PF17749.1 CDJ86815.1 - 0.0078 16.2 2.3 0.0078 16.2 2.3 2.4 3 1 0 3 3 3 1 Microtubule-binding protein MIP-T3 C-terminal region HTH_43 PF09904.9 CDJ86815.1 - 0.09 12.7 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn helix Bax1-I PF01027.20 CDJ86817.1 - 2.9e-10 40.3 21.6 3.5e-10 40.1 21.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Rota_NSP4 PF01452.16 CDJ86817.1 - 0.0027 17.4 1.1 0.0044 16.7 1.1 1.3 1 0 0 1 1 1 1 Rotavirus non structural protein Cytochrom_B_C PF00032.17 CDJ86817.1 - 0.78 10.1 10.0 0.69 10.2 7.9 1.8 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD Jagunal PF07086.12 CDJ86817.1 - 0.97 9.5 9.5 1.3 9.1 9.5 1.1 1 0 0 1 1 1 0 Jagunal, ER re-organisation during oogenesis TssN PF17555.2 CDJ86817.1 - 1 8.7 13.3 1.4 8.3 13.3 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF2070 PF09843.9 CDJ86817.1 - 1.1 7.5 19.6 1.3 7.2 19.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) YfhO PF09586.10 CDJ86817.1 - 1.5 7.0 14.9 1.7 6.7 14.9 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4499 PF14934.6 CDJ86818.1 - 1.7e-09 37.9 3.1 2.4e-09 37.4 3.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) DUF1758 PF05585.12 CDJ86820.1 - 1.6e-06 28.0 0.1 4.1e-06 26.7 0.1 1.6 1 1 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 CDJ86820.1 - 0.015 15.9 0.3 0.064 13.9 0.1 2.0 1 1 1 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 CDJ86820.1 - 0.072 13.7 0.1 0.22 12.1 0.1 1.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF1509 PF07420.11 CDJ86822.1 - 0.043 12.8 0.0 0.08 11.9 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1509) Med12-LCEWAV PF12145.8 CDJ86824.1 - 1.1e-38 133.4 4.8 1.1e-29 103.7 0.4 2.6 1 1 1 2 2 2 2 Eukaryotic Mediator 12 subunit domain Med12 PF09497.10 CDJ86824.1 - 2.7e-10 40.4 0.1 7.8e-10 38.9 0.1 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 ADK PF00406.22 CDJ86826.1 - 1.4e-32 112.9 0.0 1.9e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CDJ86826.1 - 1.2e-14 54.9 0.3 3.3e-14 53.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 CDJ86826.1 - 4e-14 52.3 0.0 9.9e-14 51.0 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 CDJ86826.1 - 8.9e-08 32.7 0.0 3.1e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ86826.1 - 0.00051 20.5 0.0 0.0015 18.9 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 CDJ86826.1 - 0.0024 17.8 0.0 0.0056 16.6 0.0 1.6 2 0 0 2 2 1 1 Adenylylsulphate kinase Sigma54_activat PF00158.26 CDJ86826.1 - 0.0036 17.0 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Cytidylate_kin PF02224.18 CDJ86826.1 - 0.0085 15.8 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase Guanylate_kin PF00625.21 CDJ86826.1 - 0.013 15.1 0.0 0.024 14.3 0.0 1.5 2 0 0 2 2 2 0 Guanylate kinase T2SSE PF00437.20 CDJ86826.1 - 0.014 14.5 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 CDJ86826.1 - 0.016 15.4 0.0 0.038 14.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDJ86826.1 - 0.017 15.6 0.0 0.023 15.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA PF00004.29 CDJ86826.1 - 0.018 15.5 0.0 0.03 14.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CDJ86826.1 - 0.028 14.7 0.0 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CDJ86826.1 - 0.052 13.1 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 CDJ86826.1 - 0.059 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Thymidylate_kin PF02223.17 CDJ86826.1 - 0.066 12.9 0.0 0.17 11.5 0.0 1.8 2 1 0 2 2 2 0 Thymidylate kinase RuvB_N PF05496.12 CDJ86826.1 - 0.067 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 CDJ86826.1 - 0.088 12.7 0.0 0.18 11.7 0.0 1.7 1 1 0 1 1 1 0 NTPase Sigma54_activ_2 PF14532.6 CDJ86826.1 - 0.09 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.15 CDJ86826.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_5 PF07728.14 CDJ86826.1 - 0.12 12.4 0.1 0.2 11.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PI3_PI4_kinase PF00454.27 CDJ86827.1 - 4.4e-45 154.5 1.7 3.1e-44 151.7 1.7 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CDJ86827.1 - 1.2e-24 86.7 0.6 2.4e-24 85.8 0.1 1.7 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 CDJ86827.1 - 3.3e-18 65.9 0.0 6.5e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 CDJ86827.1 - 7.5e-16 58.2 0.1 7.9e-15 54.9 0.0 2.4 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain PI3K_p85B PF02192.16 CDJ86827.1 - 5.3e-13 48.5 0.1 1.3e-12 47.3 0.1 1.6 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain Med8 PF10232.9 CDJ86828.1 - 1.3e-29 103.4 4.3 1.7e-29 103.1 4.3 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 PPP1R35_C PF15503.6 CDJ86829.1 - 7.2e-07 29.1 1.1 1.1e-06 28.5 1.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 1 regulatory subunit 35 C-terminus EGF_2 PF07974.13 CDJ86830.1 - 5.6e-06 26.6 18.3 0.00041 20.6 7.2 11.8 11 2 0 11 11 11 5 EGF-like domain EGF_CA PF07645.15 CDJ86830.1 - 0.00042 20.5 5.8 0.00042 20.5 5.8 10.1 8 2 3 11 11 11 1 Calcium-binding EGF domain EGF PF00008.27 CDJ86830.1 - 0.0011 19.2 3.5 0.0011 19.2 3.5 12.6 11 4 0 11 11 11 6 EGF-like domain hEGF PF12661.7 CDJ86830.1 - 1.3 9.8 92.0 0.095 13.4 4.0 12.4 12 0 0 12 12 12 0 Human growth factor-like EGF Collagen PF01391.18 CDJ86831.1 - 1.8e-21 75.7 121.0 9.8e-09 34.9 47.3 4.0 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ86831.1 - 2.2e-20 72.5 0.2 2.7e-20 72.1 0.2 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain COX14 PF14880.6 CDJ86831.1 - 0.068 13.0 2.0 0.098 12.5 2.0 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Guanylate_cyc PF00211.20 CDJ86832.1 - 1e-33 116.5 0.0 1.1e-31 109.9 0.0 2.5 1 1 1 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 CDJ86832.1 - 1.3e-33 116.6 0.2 1.8e-33 116.1 0.2 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region HNOBA PF07701.14 CDJ86832.1 - 6.5e-06 25.7 0.5 1.2e-05 24.9 0.5 1.4 1 0 0 1 1 1 1 Heme NO binding associated HTH_26 PF13443.6 CDJ86833.1 - 0.00023 21.5 0.0 0.00038 20.8 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_IclR PF09339.10 CDJ86833.1 - 0.0022 17.8 0.1 0.0035 17.1 0.1 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 CDJ86833.1 - 0.0049 16.7 0.2 0.011 15.6 0.2 1.6 1 1 0 1 1 1 1 MarR family HTH_Tnp_ISL3 PF13542.6 CDJ86833.1 - 0.02 14.3 0.1 0.038 13.4 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.6 CDJ86833.1 - 0.027 14.0 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding LacI PF00356.21 CDJ86833.1 - 0.029 14.1 0.6 0.19 11.6 0.1 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family CENP-B_N PF04218.13 CDJ86833.1 - 0.031 13.9 0.0 0.05 13.2 0.0 1.5 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_3 PF01381.22 CDJ86833.1 - 0.031 14.3 0.0 0.09 12.8 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix DUF3602 PF12223.8 CDJ86833.1 - 0.04 14.5 0.4 0.065 13.8 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) HTH_10 PF04967.12 CDJ86833.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain RNA_pol_Rpc4 PF05132.14 CDJ86833.1 - 0.16 12.4 0.0 0.19 12.1 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 PKcGMP_CC PF16808.5 CDJ86833.1 - 0.17 11.8 1.3 0.29 11.0 1.3 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4572 PF15139.6 CDJ86833.1 - 0.18 11.7 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4572) RVT_1 PF00078.27 CDJ86834.1 - 2.3e-07 30.5 0.1 2.6e-07 30.4 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) V-SNARE PF05008.15 CDJ86835.1 - 0.002 18.5 0.3 0.0029 17.9 0.3 1.4 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus DUF4376 PF14301.6 CDJ86835.1 - 0.027 14.8 0.5 0.042 14.2 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4376) DUF724 PF05266.14 CDJ86835.1 - 0.032 14.1 0.9 0.041 13.7 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DDE_Tnp_1_7 PF13843.6 CDJ86837.1 - 1.1e-15 57.8 0.2 1.3e-15 57.5 0.2 1.1 1 0 0 1 1 1 1 Transposase IS4 DDE_3 PF13358.6 CDJ86838.1 - 3.2e-12 46.4 0.0 7.8e-12 45.2 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease zf-C4H2 PF10146.9 CDJ86838.1 - 0.0013 19.1 0.5 0.0013 19.1 0.5 1.7 2 1 0 2 2 2 1 Zinc finger-containing protein RhoGAP PF00620.27 CDJ86841.1 - 1.1e-13 51.2 0.1 1.8e-13 50.6 0.1 1.2 1 0 0 1 1 1 1 RhoGAP domain eIF-5_eIF-2B PF01873.17 CDJ86842.1 - 0.059 13.2 0.2 0.19 11.6 0.3 1.7 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Epiglycanin_C PF14654.6 CDJ86843.1 - 0.2 11.7 1.5 4.5 7.4 0.0 2.9 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Zip PF02535.22 CDJ86844.1 - 6.2 5.9 7.4 6.5 5.9 7.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PSRT PF07636.11 CDJ86845.1 - 0.4 10.4 5.1 0.26 11.0 0.5 2.5 2 0 0 2 2 2 0 PSRT CoA_binding PF02629.19 CDJ86846.1 - 2.9e-32 111.2 1.7 2.9e-32 111.2 1.7 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 CDJ86846.1 - 3.5e-23 82.1 0.1 7.2e-23 81.1 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 CDJ86846.1 - 3.9e-07 30.0 0.0 8e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CDJ86846.1 - 7.8e-06 26.4 0.0 3.2e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Mrr_cat PF04471.12 CDJ86846.1 - 0.13 12.3 0.1 0.57 10.2 0.0 2.0 2 0 0 2 2 2 0 Restriction endonuclease Thioredoxin PF00085.20 CDJ86847.1 - 2.1e-11 43.7 0.0 3.1e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 CDJ86847.1 - 0.0018 18.2 0.0 0.0025 17.7 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 CDJ86847.1 - 0.054 13.9 0.1 0.2 12.1 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain Glutaredoxin PF00462.24 CDJ86847.1 - 0.079 13.2 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin Pkinase PF00069.25 CDJ86848.1 - 2.9e-26 92.4 0.0 3.6e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ86848.1 - 2.1e-13 50.2 0.1 2.5e-13 49.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ86848.1 - 0.00012 22.1 0.1 0.00056 19.9 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 CDJ86848.1 - 0.0015 18.2 0.0 0.18 11.4 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CDJ86848.1 - 0.0024 17.3 0.1 0.0041 16.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 CDJ86848.1 - 0.037 13.7 0.1 0.071 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Polyketide_cyc PF03364.20 CDJ86849.1 - 0.07 13.3 0.0 0.092 13.0 0.0 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport EF-hand_11 PF08976.11 CDJ86849.1 - 0.11 13.3 0.1 1.3 9.9 0.2 2.1 2 0 0 2 2 2 0 EF-hand domain AAA PF00004.29 CDJ86851.1 - 3.4e-16 59.9 0.0 6.5e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ86851.1 - 1.1e-09 38.6 0.0 3.3e-09 37.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 CDJ86851.1 - 3.5e-09 37.3 0.0 7.5e-08 32.9 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 CDJ86851.1 - 1.8e-06 28.0 0.0 3.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 CDJ86851.1 - 8.2e-06 26.2 0.2 4.4e-05 23.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CDJ86851.1 - 1.8e-05 24.2 0.0 2.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_lid_10 PF17872.1 CDJ86851.1 - 4.9e-05 23.4 1.6 9.6e-05 22.4 0.3 2.1 2 0 0 2 2 1 1 AAA lid domain ATPase_2 PF01637.18 CDJ86851.1 - 0.00017 21.6 0.1 0.00049 20.1 0.1 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 CDJ86851.1 - 0.00097 18.5 0.4 0.22 10.7 0.0 2.4 1 1 1 2 2 2 2 KAP family P-loop domain AAA_11 PF13086.6 CDJ86851.1 - 0.0014 18.5 0.4 0.0045 16.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 CDJ86851.1 - 0.0041 17.1 0.1 0.027 14.5 0.1 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit TIP49 PF06068.13 CDJ86851.1 - 0.0077 15.5 0.3 0.12 11.6 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain NB-ARC PF00931.22 CDJ86851.1 - 0.02 14.1 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ORC4_C PF14629.6 CDJ86851.1 - 0.02 14.3 0.1 0.044 13.1 0.1 1.5 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus AAA_18 PF13238.6 CDJ86851.1 - 0.025 15.1 0.0 0.079 13.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 CDJ86851.1 - 0.048 13.4 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CDJ86851.1 - 0.052 12.6 0.0 0.13 11.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein MeaB PF03308.16 CDJ86851.1 - 0.079 11.9 0.1 0.16 11.0 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_32 PF13654.6 CDJ86851.1 - 0.086 11.6 0.2 0.22 10.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain Guanylate_cyc PF00211.20 CDJ86853.1 - 1.2e-37 129.4 0.0 8.7e-22 77.6 0.0 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain S_4TM PF18159.1 CDJ86853.1 - 0.034 13.4 0.1 0.095 12.0 0.1 1.7 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain Phosphodiest PF01663.22 CDJ86854.1 - 1e-48 166.8 1.4 1.2e-48 166.5 1.4 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CDJ86854.1 - 7.1e-06 25.6 0.1 0.0015 18.0 0.1 2.2 2 0 0 2 2 2 2 Sulfatase CAF1A PF12253.8 CDJ86854.1 - 0.027 14.7 0.4 2.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A Metalloenzyme PF01676.18 CDJ86854.1 - 0.077 12.3 0.2 0.12 11.7 0.2 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily RT_RNaseH PF17917.1 CDJ86855.1 - 5.2e-35 119.9 0.0 1.4e-34 118.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ86855.1 - 3.2e-24 84.9 0.0 7.7e-24 83.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Apolipoprotein PF01442.18 CDJ86855.1 - 0.014 15.2 8.0 1.1 9.1 0.1 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain LURAP PF14854.6 CDJ86855.1 - 0.022 14.7 0.9 0.55 10.2 0.9 2.2 1 1 0 1 1 1 0 Leucine rich adaptor protein Blo-t-5 PF11642.8 CDJ86855.1 - 0.026 14.5 1.0 0.054 13.5 1.0 1.5 1 0 0 1 1 1 0 Mite allergen Blo t 5 TINF2_N PF14973.6 CDJ86855.1 - 0.047 14.0 1.7 0.19 12.1 0.4 2.0 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus DUF4265 PF14085.6 CDJ86855.1 - 0.052 13.5 0.2 15 5.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) Sugar-bind PF04198.13 CDJ86855.1 - 0.088 11.9 0.2 0.19 10.8 0.1 1.6 2 0 0 2 2 2 0 Putative sugar-binding domain Mito_fiss_reg PF05308.11 CDJ86855.1 - 0.1 12.7 3.2 0.16 12.0 3.2 1.3 1 1 0 1 1 1 0 Mitochondrial fission regulator DUF1045 PF06299.12 CDJ86855.1 - 0.21 11.6 1.9 0.58 10.1 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) DUF3037 PF11236.8 CDJ86855.1 - 0.22 11.9 1.7 0.5 10.8 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) THOC7 PF05615.13 CDJ86855.1 - 0.27 11.5 7.5 5.3 7.3 3.7 2.2 2 0 0 2 2 2 0 Tho complex subunit 7 GAS PF13851.6 CDJ86855.1 - 0.35 10.2 7.2 0.74 9.1 2.8 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding UPF0184 PF03670.13 CDJ86855.1 - 0.6 10.5 3.4 2.9 8.4 0.1 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) DUF883 PF05957.13 CDJ86855.1 - 0.71 10.5 3.9 7.6 7.2 1.5 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) PRKG1_interact PF15898.5 CDJ86855.1 - 0.77 10.7 5.8 0.73 10.8 1.8 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain AAA_32 PF13654.6 CDJ86855.1 - 0.92 8.2 5.0 1.2 7.8 5.0 1.1 1 0 0 1 1 1 0 AAA domain Csm1_N PF18504.1 CDJ86855.1 - 1.6 9.1 8.4 0.4 11.1 4.4 1.9 2 0 0 2 2 2 0 Csm1 N-terminal domain ATP-synt_B PF00430.18 CDJ86855.1 - 2.6 8.1 10.1 1.8 8.7 0.5 2.2 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DUF5339 PF17274.2 CDJ86855.1 - 2.7 8.9 7.2 1.8 9.4 3.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5339) TRAP-delta PF05404.12 CDJ86856.1 - 0.089 12.3 0.0 0.2 11.2 0.0 1.5 1 1 0 1 1 1 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) PDZ_6 PF17820.1 CDJ86857.1 - 1.1e-23 82.8 0.2 1.9e-12 46.8 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 CDJ86857.1 - 1.5e-19 70.1 3.1 6e-09 36.1 0.0 3.3 4 0 0 4 4 4 2 PDZ domain PDZ_2 PF13180.6 CDJ86857.1 - 7.7e-08 32.6 0.0 0.00019 21.7 0.0 2.7 2 0 0 2 2 2 2 PDZ domain EBP50_C PF09007.11 CDJ86857.1 - 0.2 12.7 9.0 0.031 15.3 3.9 2.2 1 1 1 2 2 2 0 EBP50, C-terminal Exo_endo_phos_2 PF14529.6 CDJ86858.1 - 6.1e-05 22.8 0.0 0.00017 21.4 0.0 1.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ86858.1 - 0.0057 16.2 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YdaT_toxin PF06254.11 CDJ86858.1 - 0.1 13.2 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative bacterial toxin ydaT DNA_methylase PF00145.17 CDJ86861.1 - 4e-39 134.9 0.0 2.4e-38 132.3 0.0 1.8 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Ras PF00071.22 CDJ86862.1 - 1.5e-22 80.0 0.0 1.6e-22 79.8 0.0 1.0 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.18 CDJ86862.1 - 0.037 13.5 0.1 0.062 12.8 0.0 1.4 1 1 0 1 1 1 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CDJ86862.1 - 0.046 13.6 0.1 0.062 13.2 0.1 1.2 1 0 0 1 1 1 0 RsgA GTPase Claudin_2 PF13903.6 CDJ86866.1 - 0.00061 19.6 2.0 0.00061 19.6 2.0 1.9 1 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Sid-5 PF17204.3 CDJ86866.1 - 0.26 11.5 0.1 0.26 11.5 0.1 2.7 2 1 1 3 3 3 0 Sid-5 family GlpM PF06942.12 CDJ86866.1 - 0.5 10.8 12.7 0.66 10.4 12.7 1.2 1 0 0 1 1 1 0 GlpM protein Orf78 PF06024.12 CDJ86866.1 - 1.1 9.6 0.0 1.1 9.6 0.0 3.2 1 1 1 3 3 3 0 Orf78 (ac78) Peptidase_U4 PF03419.13 CDJ86866.1 - 5.2 6.3 15.1 7 5.9 15.1 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA CHCH PF06747.13 CDJ86867.1 - 2.1e-08 34.1 4.9 3.5e-08 33.4 4.9 1.4 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 CDJ86867.1 - 0.36 10.9 4.7 7.2 6.7 4.7 2.2 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like SDF PF00375.18 CDJ86868.1 - 5.8e-23 81.5 5.9 6.7e-23 81.3 5.9 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family SLATT_3 PF18184.1 CDJ86868.1 - 0.083 13.0 0.9 0.11 12.6 0.9 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 3 SDF PF00375.18 CDJ86869.1 - 2.1e-29 102.7 4.6 2.6e-29 102.5 4.6 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family HlyE PF06109.13 CDJ86869.1 - 0.018 14.4 0.1 0.022 14.1 0.1 1.1 1 0 0 1 1 1 0 Haemolysin E (HlyE) SLATT_3 PF18184.1 CDJ86869.1 - 0.044 13.9 1.2 0.081 13.1 1.2 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 3 DUF4064 PF13273.6 CDJ86869.1 - 0.11 12.8 5.0 0.19 12.0 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF4199 PF13858.6 CDJ86869.1 - 4 7.8 9.6 0.37 11.2 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) DUF1041 PF06292.17 CDJ86870.1 - 0.0081 16.5 0.0 0.01 16.2 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1041) FAD_binding_5 PF00941.21 CDJ86871.1 - 8.1e-42 142.8 0.0 1.4e-41 142.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 CDJ86871.1 - 2.4e-31 107.6 0.1 5.8e-31 106.4 0.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 CDJ86871.1 - 5.1e-09 36.2 0.0 1.5e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 CDJ86871.1 - 8.6e-08 32.0 0.3 8.6e-08 32.0 0.3 2.4 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Sulfotransfer_3 PF13469.6 CDJ86871.1 - 0.051 13.9 0.0 0.09 13.2 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase family SH2 PF00017.24 CDJ86872.1 - 3.6e-24 84.6 0.1 5e-24 84.2 0.1 1.2 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 CDJ86872.1 - 1.9e-15 56.2 0.0 8.1e-15 54.2 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CDJ86872.1 - 7.5e-14 51.3 0.0 1.5e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CDJ86872.1 - 4.8e-09 35.8 0.0 1.1e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 CDJ86872.1 - 0.017 15.4 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain hSH3 PF14603.6 CDJ86872.1 - 0.1 13.1 0.0 0.57 10.6 0.0 2.1 1 1 1 2 2 2 0 Helically-extended SH3 domain zf-BED PF02892.15 CDJ86873.1 - 1.3e-08 34.7 0.7 3e-08 33.6 0.7 1.7 1 0 0 1 1 1 1 BED zinc finger Utp12 PF04003.12 CDJ86874.1 - 7.3e-16 58.4 3.2 1e-15 58.0 3.2 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family UTP15_C PF09384.10 CDJ86874.1 - 0.11 12.2 0.4 0.19 11.4 0.4 1.4 1 0 0 1 1 1 0 UTP15 C terminal GTP_EFTU PF00009.27 CDJ86876.1 - 5.3e-21 75.0 0.0 8.9e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CDJ86876.1 - 7.1e-07 29.5 0.0 2.1e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 ATP_bind_1 PF03029.17 CDJ86876.1 - 0.0047 16.7 0.1 0.36 10.6 0.1 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 CDJ86876.1 - 0.012 15.5 0.0 0.09 12.7 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 CDJ86876.1 - 0.087 12.6 0.1 6.2 6.6 0.0 3.1 3 1 1 4 4 4 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 CDJ86876.1 - 0.16 12.1 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase 7tm_1 PF00001.21 CDJ86877.1 - 3.3e-58 197.1 0.3 4.6e-58 196.6 0.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDJ86877.1 - 0.024 13.9 5.7 0.14 11.4 0.0 2.5 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw FAM60A PF15396.6 CDJ86877.1 - 0.077 13.0 2.2 0.1 12.6 2.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF3693 PF12472.8 CDJ86877.1 - 0.2 11.3 1.5 0.43 10.3 1.5 1.5 1 0 0 1 1 1 0 Phage related protein FA_desaturase PF00487.24 CDJ86877.1 - 0.92 9.3 0.0 0.92 9.3 0.0 2.3 2 1 1 3 3 3 0 Fatty acid desaturase Guanylate_kin PF00625.21 CDJ86878.1 - 5.7e-36 123.9 0.0 9.3e-33 113.4 0.0 2.4 1 1 0 2 2 2 2 Guanylate kinase PDZ PF00595.24 CDJ86878.1 - 1.8e-11 44.2 0.1 4.1e-11 43.1 0.1 1.6 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDJ86878.1 - 1.1e-08 34.8 0.3 3.9e-08 33.0 0.2 2.0 2 0 0 2 2 2 1 PDZ domain SH3_1 PF00018.28 CDJ86878.1 - 1.7e-06 27.5 1.0 9.3e-06 25.2 0.7 2.4 2 1 0 2 2 2 1 SH3 domain AAA_5 PF07728.14 CDJ86878.1 - 0.0006 19.8 0.0 0.0027 17.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) SH3_9 PF14604.6 CDJ86878.1 - 0.0063 16.4 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PDZ_2 PF13180.6 CDJ86878.1 - 0.0087 16.4 0.1 0.021 15.1 0.1 1.6 1 0 0 1 1 1 1 PDZ domain ApoLp-III PF07464.11 CDJ86878.1 - 0.019 15.0 0.1 0.033 14.3 0.1 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) AAA_22 PF13401.6 CDJ86878.1 - 0.14 12.4 0.0 0.98 9.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain TFA2_Winged_2 PF18121.1 CDJ86878.1 - 0.17 11.6 0.3 8.7 6.1 0.1 2.9 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 NEMP PF10225.9 CDJ86879.1 - 5e-60 203.3 7.5 1e-59 202.2 7.5 1.5 1 0 0 1 1 1 1 NEMP family Syndecan PF01034.20 CDJ86879.1 - 0.34 10.9 1.5 1.1 9.2 1.1 2.2 1 1 0 1 1 1 0 Syndecan domain GDPD PF03009.17 CDJ86880.1 - 1.3e-42 146.3 0.0 1.9e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Gp-FAR-1 PF05823.12 CDJ86881.1 - 6.4e-40 136.9 7.3 7.3e-40 136.7 7.3 1.0 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ApoLp-III PF07464.11 CDJ86881.1 - 3.9e-05 23.8 2.3 0.00017 21.7 0.2 2.3 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) DUF3106 PF11304.8 CDJ86881.1 - 0.0003 21.2 3.4 0.065 13.7 0.3 2.4 1 1 2 3 3 3 3 Protein of unknown function (DUF3106) Syntaxin PF00804.25 CDJ86881.1 - 0.0015 18.2 3.0 0.0022 17.7 3.0 1.2 1 0 0 1 1 1 1 Syntaxin Mod_r PF07200.13 CDJ86881.1 - 0.002 18.3 2.8 0.0026 17.9 2.8 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Syntaxin_2 PF14523.6 CDJ86881.1 - 0.0061 16.9 0.5 0.013 15.8 0.5 1.6 1 1 0 1 1 1 1 Syntaxin-like protein SHE3 PF17078.5 CDJ86881.1 - 0.016 14.9 3.5 0.02 14.6 3.5 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 ZnuA PF01297.17 CDJ86881.1 - 0.053 12.9 2.7 0.07 12.5 2.7 1.2 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic F-actin_cap_A PF01267.17 CDJ86881.1 - 0.063 12.7 1.1 0.18 11.2 0.1 1.9 1 1 0 2 2 2 0 F-actin capping protein alpha subunit SurA_N PF09312.11 CDJ86881.1 - 0.098 12.7 0.7 0.54 10.4 0.1 2.1 2 0 0 2 2 2 0 SurA N-terminal domain DUF4085 PF13315.6 CDJ86881.1 - 0.11 12.1 1.7 2.6 7.6 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF4085) kleA_kleC PF17383.2 CDJ86881.1 - 0.13 12.6 2.0 0.95 9.8 0.7 2.3 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A OmpH PF03938.14 CDJ86881.1 - 0.14 12.5 6.5 0.27 11.5 6.5 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) TPR_MLP1_2 PF07926.12 CDJ86881.1 - 0.5 10.4 5.8 0.73 9.9 4.0 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Gp-FAR-1 PF05823.12 CDJ86882.1 - 6.1e-37 127.3 5.7 7.2e-37 127.0 5.7 1.0 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF3106 PF11304.8 CDJ86882.1 - 9.5e-06 26.0 0.2 0.00018 21.9 0.2 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF3106) ApoLp-III PF07464.11 CDJ86882.1 - 0.0015 18.6 2.0 0.13 12.4 0.6 2.5 2 1 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) TipAS PF07739.13 CDJ86882.1 - 0.0018 18.8 2.6 0.0042 17.6 2.6 1.7 1 1 0 1 1 1 1 TipAS antibiotic-recognition domain EF-G-binding_N PF07299.11 CDJ86882.1 - 0.006 17.1 0.8 0.55 10.8 0.0 2.8 3 0 0 3 3 3 1 Elongation factor G-binding protein, N-terminal DUF4297 PF14130.6 CDJ86882.1 - 0.0068 16.6 0.1 0.011 15.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4297) P63C PF10546.9 CDJ86882.1 - 0.014 16.0 0.2 0.046 14.3 0.1 1.9 2 1 0 2 2 2 0 P63C domain Ferritin-like PF12902.7 CDJ86882.1 - 0.024 14.5 0.2 0.032 14.1 0.2 1.1 1 0 0 1 1 1 0 Ferritin-like DUF4473 PF14747.6 CDJ86882.1 - 0.027 15.0 2.5 0.69 10.5 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) SieB PF14163.6 CDJ86882.1 - 0.031 13.8 0.0 4.2 6.9 0.0 2.4 2 0 0 2 2 2 0 Super-infection exclusion protein B DUF87 PF01935.17 CDJ86882.1 - 0.032 14.3 0.2 0.042 13.9 0.2 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain Mu-like_Pro PF10123.9 CDJ86882.1 - 0.073 12.6 2.2 0.11 12.0 2.2 1.3 1 1 0 1 1 1 0 Mu-like prophage I protein LTXXQ PF07813.12 CDJ86882.1 - 0.076 13.7 0.8 13 6.6 0.0 2.5 2 1 0 2 2 2 0 LTXXQ motif family protein DUF948 PF06103.11 CDJ86882.1 - 0.14 12.5 0.0 3.1 8.1 0.0 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Syntaxin_2 PF14523.6 CDJ86882.1 - 0.15 12.5 0.7 0.65 10.4 0.1 2.1 1 1 1 2 2 2 0 Syntaxin-like protein ZYG-11_interact PF05884.12 CDJ86882.1 - 0.15 11.4 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 NepR PF18557.1 CDJ86882.1 - 0.65 9.7 0.0 0.65 9.7 0.0 2.3 2 0 0 2 2 2 0 Anti-sigma factor NepR Gp-FAR-1 PF05823.12 CDJ86883.1 - 1.6e-36 125.9 2.2 1.9e-36 125.6 2.2 1.0 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ApoLp-III PF07464.11 CDJ86883.1 - 0.0016 18.5 0.0 0.0024 17.9 0.0 1.4 1 1 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) Dynamin_M PF01031.20 CDJ86883.1 - 0.0033 16.7 0.1 0.0054 16.0 0.1 1.4 1 1 0 1 1 1 1 Dynamin central region DUF3106 PF11304.8 CDJ86883.1 - 0.034 14.6 0.2 0.25 11.8 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) Myb_DNA-bind_4 PF13837.6 CDJ86883.1 - 0.036 14.4 0.2 0.2 12.1 0.0 1.9 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Gp-FAR-1 PF05823.12 CDJ86884.1 - 3.9e-36 124.6 1.9 4.6e-36 124.4 1.9 1.0 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ApoLp-III PF07464.11 CDJ86884.1 - 3.9e-05 23.8 0.1 0.00011 22.4 0.1 1.6 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) DUF3106 PF11304.8 CDJ86884.1 - 0.00012 22.5 0.4 0.00059 20.3 0.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3106) DUF1043 PF06295.12 CDJ86884.1 - 0.038 14.0 0.5 0.056 13.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Tox-ODYAM1 PF15642.6 CDJ86884.1 - 0.044 12.8 0.1 0.072 12.1 0.1 1.3 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Dynamin_M PF01031.20 CDJ86884.1 - 0.056 12.7 0.1 0.062 12.5 0.1 1.3 1 0 0 1 1 1 0 Dynamin central region Armet PF10208.9 CDJ86884.1 - 0.058 13.3 0.1 0.2 11.6 0.0 1.7 1 1 1 2 2 2 0 Degradation arginine-rich protein for mis-folding Myb_DNA-bind_4 PF13837.6 CDJ86884.1 - 0.097 13.1 0.0 0.27 11.6 0.0 1.6 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Gp-FAR-1 PF05823.12 CDJ86885.1 - 1.7e-49 168.0 12.0 2e-49 167.8 12.0 1.0 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ApoLp-III PF07464.11 CDJ86885.1 - 1.2e-05 25.4 6.1 0.01 15.9 0.5 2.3 1 1 1 2 2 2 2 Apolipophorin-III precursor (apoLp-III) Syntaxin PF00804.25 CDJ86885.1 - 0.00034 20.4 1.3 0.00045 19.9 1.3 1.1 1 0 0 1 1 1 1 Syntaxin Apolipoprotein PF01442.18 CDJ86885.1 - 0.00066 19.6 2.3 0.001 19.0 2.3 1.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain CdvA PF18822.1 CDJ86885.1 - 0.0069 16.2 5.7 0.29 10.9 0.7 3.0 2 1 1 3 3 3 1 CdvA-like coiled-coil domain DUF3106 PF11304.8 CDJ86885.1 - 0.023 15.1 1.1 1.5 9.4 0.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) TetR_C_3 PF08362.11 CDJ86885.1 - 0.024 14.6 0.6 0.043 13.7 0.5 1.6 1 1 0 1 1 1 0 YcdC-like protein, C-terminal region SieB PF14163.6 CDJ86885.1 - 0.04 13.4 0.5 2.2 7.8 0.0 2.3 1 1 1 2 2 2 0 Super-infection exclusion protein B GA PF01468.17 CDJ86885.1 - 0.085 13.2 4.6 0.36 11.1 1.4 2.9 3 0 0 3 3 3 0 GA module DUF2063 PF09836.9 CDJ86885.1 - 0.13 12.5 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 Putative DNA-binding domain Cytochrom_C_2 PF01322.20 CDJ86885.1 - 1.6 9.7 8.8 1.9 9.4 5.7 2.3 1 1 1 2 2 2 0 Cytochrome C' ZapB PF06005.12 CDJ86885.1 - 1.7 9.1 6.7 5.2 7.6 0.7 2.7 2 2 0 2 2 2 0 Cell division protein ZapB YtxH PF12732.7 CDJ86885.1 - 3.1 8.4 12.8 13 6.4 6.3 3.0 1 1 1 2 2 2 0 YtxH-like protein Pkinase PF00069.25 CDJ86886.1 - 1.8e-12 47.2 0.1 1.1e-10 41.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain ABC_tran PF00005.27 CDJ86887.1 - 8.6e-56 188.2 0.0 8.7e-18 65.2 0.0 3.5 3 1 0 3 3 3 3 ABC transporter AAA_21 PF13304.6 CDJ86887.1 - 1.1e-14 55.0 4.9 0.3 10.8 1.0 6.1 4 2 2 6 6 6 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDJ86887.1 - 2e-14 53.6 16.2 0.00048 19.6 0.6 5.8 4 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain RLI PF04068.15 CDJ86887.1 - 1.2e-10 41.1 5.2 2.8e-10 39.8 5.2 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_16 PF13191.6 CDJ86887.1 - 7.5e-10 39.4 0.0 0.024 15.0 0.0 3.5 3 0 0 3 3 3 3 AAA ATPase domain RsgA_GTPase PF03193.16 CDJ86887.1 - 4.2e-09 36.5 0.2 0.13 12.2 0.0 3.8 3 0 0 3 3 3 3 RsgA GTPase AAA PF00004.29 CDJ86887.1 - 1e-08 35.7 0.0 0.094 13.1 0.0 3.9 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 CDJ86887.1 - 3.5e-08 33.5 0.2 0.45 10.2 0.0 3.7 4 0 0 4 4 3 3 AAA ATPase domain AAA_22 PF13401.6 CDJ86887.1 - 2.5e-07 31.0 0.0 0.016 15.5 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 CDJ86887.1 - 2.7e-07 31.3 0.1 0.01 16.4 0.1 3.5 3 0 0 3 3 3 1 AAA domain Fer4 PF00037.27 CDJ86887.1 - 3.1e-07 29.9 3.9 3.1e-07 29.9 3.9 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Rad17 PF03215.15 CDJ86887.1 - 1e-06 28.8 0.0 0.6 10.0 0.0 3.5 3 0 0 3 3 3 2 Rad17 P-loop domain NB-ARC PF00931.22 CDJ86887.1 - 6.4e-06 25.5 0.0 0.25 10.5 0.0 3.3 3 0 0 3 3 3 2 NB-ARC domain RNA_helicase PF00910.22 CDJ86887.1 - 8.5e-06 26.1 0.1 1.6 9.2 0.0 3.7 3 0 0 3 3 3 1 RNA helicase MeaB PF03308.16 CDJ86887.1 - 8.8e-06 24.9 1.6 0.0059 15.6 0.0 2.8 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 CDJ86887.1 - 1.6e-05 24.5 4.2 0.9 9.3 0.0 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain Fer4_7 PF12838.7 CDJ86887.1 - 1.8e-05 25.2 6.2 0.00014 22.3 0.4 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain NACHT PF05729.12 CDJ86887.1 - 3.1e-05 23.9 2.4 0.59 10.0 0.0 3.7 3 0 0 3 3 3 1 NACHT domain AAA_33 PF13671.6 CDJ86887.1 - 3.3e-05 24.1 0.0 1.3 9.2 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 CDJ86887.1 - 3.5e-05 24.4 0.5 8.4 7.0 0.1 4.2 3 2 0 3 3 3 0 AAA domain SRP54 PF00448.22 CDJ86887.1 - 4.9e-05 23.0 6.0 0.15 11.7 0.0 3.3 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 CDJ86887.1 - 7.1e-05 23.0 0.2 12 6.3 0.0 4.0 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit TsaE PF02367.17 CDJ86887.1 - 7.1e-05 22.8 0.2 0.033 14.2 0.0 3.6 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_6 PF12837.7 CDJ86887.1 - 8.1e-05 22.5 2.8 8.1e-05 22.5 2.8 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_28 PF13521.6 CDJ86887.1 - 0.00013 22.3 0.2 2.8 8.2 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 CDJ86887.1 - 0.00014 21.4 0.1 0.027 14.0 0.0 3.2 3 0 0 3 3 3 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 CDJ86887.1 - 0.00042 20.4 2.9 0.61 10.2 0.0 3.5 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_14 PF13173.6 CDJ86887.1 - 0.00069 19.7 0.1 9.9 6.2 0.0 4.2 3 1 0 3 3 3 0 AAA domain Fer4_21 PF14697.6 CDJ86887.1 - 0.00082 19.5 13.1 0.0016 18.5 13.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_30 PF13604.6 CDJ86887.1 - 0.00088 19.0 2.1 1.5 8.5 0.0 3.6 3 0 0 3 3 3 1 AAA domain Fer4_16 PF13484.6 CDJ86887.1 - 0.0011 19.9 7.1 0.0046 17.9 0.3 2.6 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 CDJ86887.1 - 0.0012 19.0 11.8 0.0023 18.1 11.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_5 PF07728.14 CDJ86887.1 - 0.0013 18.7 0.9 0.88 9.6 0.0 3.9 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.17 CDJ86887.1 - 0.0016 18.1 0.0 21 4.7 0.0 3.5 3 0 0 3 3 3 0 Thymidylate kinase VirE PF05272.11 CDJ86887.1 - 0.0035 17.1 0.2 6.8 6.4 0.0 3.4 3 0 0 3 3 3 0 Virulence-associated protein E AAA_24 PF13479.6 CDJ86887.1 - 0.01 15.6 6.3 2.2 8.0 0.0 3.6 3 0 0 3 3 3 0 AAA domain OB_aCoA_assoc PF01796.17 CDJ86887.1 - 0.013 15.5 0.6 8.8 6.4 0.1 2.7 2 0 0 2 2 2 0 DUF35 OB-fold domain, acyl-CoA-associated Fer4_10 PF13237.6 CDJ86887.1 - 0.018 15.2 2.0 0.018 15.2 2.0 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 CDJ86887.1 - 0.023 14.8 1.8 0.023 14.8 1.8 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 CDJ86887.1 - 0.029 14.9 1.0 0.029 14.9 1.0 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain DUF815 PF05673.13 CDJ86887.1 - 0.033 13.3 0.4 21 4.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF815) TniB PF05621.11 CDJ86887.1 - 0.053 12.9 0.1 3.2 7.1 0.1 3.1 3 0 0 3 3 3 0 Bacterial TniB protein MukB PF04310.12 CDJ86887.1 - 0.057 13.2 2.3 48 3.6 0.0 3.6 3 0 0 3 3 3 0 MukB N-terminal Proho_convert PF12177.8 CDJ86887.1 - 0.093 12.7 0.0 24 5.0 0.0 2.4 2 0 0 2 2 2 0 Prohormone convertase enzyme AAA_13 PF13166.6 CDJ86887.1 - 0.1 11.2 0.0 0.51 8.9 0.0 2.2 1 0 0 1 1 1 0 AAA domain Fer4_4 PF12800.7 CDJ86887.1 - 0.1 13.1 12.9 0.39 11.4 2.9 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Zeta_toxin PF06414.12 CDJ86887.1 - 0.11 11.7 1.7 4.4 6.5 0.0 3.3 3 0 0 3 3 3 0 Zeta toxin KAP_NTPase PF07693.14 CDJ86887.1 - 0.15 11.3 0.0 27 3.9 0.0 3.0 3 0 0 3 3 3 0 KAP family P-loop domain PilN_bio_d PF18222.1 CDJ86887.1 - 0.16 12.3 0.1 36 4.8 0.0 2.5 2 0 0 2 2 2 0 PilN biogenesis protein dimerization domain Fer4_8 PF13183.6 CDJ86887.1 - 0.18 12.3 0.2 0.18 12.3 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_19 PF13245.6 CDJ86887.1 - 0.39 11.0 3.3 1.8 8.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain Fer4_3 PF12798.7 CDJ86887.1 - 0.49 11.5 16.0 0.11 13.5 4.5 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain HHH_5 PF14520.6 CDJ86887.1 - 0.72 10.5 3.7 29 5.3 0.3 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix domain Roc PF08477.13 CDJ86887.1 - 0.84 9.9 3.9 1.7 8.9 0.0 3.0 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase TrwB_AAD_bind PF10412.9 CDJ86887.1 - 2.1 7.1 4.3 18 4.1 0.0 3.0 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.15 CDJ86887.1 - 5.3 6.9 11.8 15 5.5 0.0 4.7 5 0 0 5 5 4 0 NTPase MobB PF03205.14 CDJ86887.1 - 8.6 6.3 5.9 18 5.2 0.0 3.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Glycos_transf_2 PF00535.26 CDJ86888.1 - 8.2e-38 129.9 0.0 1.6e-37 128.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CDJ86888.1 - 7.4e-08 32.6 0.0 1.2e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 CDJ86888.1 - 1.9e-05 24.2 0.3 5.9e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CDJ86888.1 - 0.059 12.8 0.0 0.17 11.3 0.0 1.9 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Ricin_B_lectin PF00652.22 CDJ86888.1 - 0.059 13.6 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain DUF1670 PF07900.11 CDJ86888.1 - 0.12 11.7 0.0 0.31 10.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1670) PP2C PF00481.21 CDJ86891.1 - 1e-67 228.5 1.5 8.7e-56 189.4 0.7 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 CDJ86891.1 - 4e-05 23.4 0.0 0.01 15.5 0.0 3.0 2 1 0 2 2 2 2 Protein phosphatase 2C GYF PF02213.16 CDJ86892.1 - 3.9e-08 32.8 0.0 9.5e-08 31.6 0.0 1.7 1 0 0 1 1 1 1 GYF domain FYVE PF01363.21 CDJ86893.1 - 3.5e-19 68.7 8.4 6.8e-19 67.8 8.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 CDJ86893.1 - 4.4e-09 36.8 0.0 7.2e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.16 CDJ86893.1 - 0.0041 17.3 4.8 0.0082 16.3 4.8 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger PH_13 PF16652.5 CDJ86893.1 - 0.0075 16.1 0.8 0.25 11.1 0.8 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_16 PF17838.1 CDJ86893.1 - 0.021 14.7 0.1 0.16 11.8 0.1 2.0 1 1 0 1 1 1 0 PH domain IQ_SEC7_PH PF16453.5 CDJ86893.1 - 0.034 14.1 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 PH domain Ephrin_rec_like PF07699.13 CDJ86893.1 - 0.085 12.6 4.5 0.6 9.9 0.7 2.5 1 1 1 2 2 2 0 Putative ephrin-receptor like DZR PF12773.7 CDJ86893.1 - 2.1 8.4 10.1 18 5.4 0.6 2.8 1 1 1 2 2 2 0 Double zinc ribbon zf-B_box PF00643.24 CDJ86893.1 - 4.7 7.4 9.2 1.6 9.0 5.4 2.0 2 1 0 2 2 2 0 B-box zinc finger HA2 PF04408.23 CDJ86894.1 - 2.3e-21 76.1 0.0 4.8e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CDJ86894.1 - 1.8e-15 57.3 0.0 4.2e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CDJ86894.1 - 1.7e-07 31.5 0.0 3.8e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CDJ86894.1 - 4.2e-05 23.4 0.0 8.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDJ86894.1 - 0.00065 20.0 0.1 0.004 17.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ86894.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDJ86894.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 CDJ86894.1 - 0.19 12.2 0.2 0.46 11.0 0.2 1.7 1 1 0 1 1 1 0 ABC transporter P34-Arc PF04045.14 CDJ86895.1 - 2.6e-102 341.6 0.1 3.1e-102 341.4 0.1 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 CDJ86895.1 - 0.017 14.7 0.2 0.078 12.6 0.1 2.0 2 1 0 2 2 2 0 ARP2/3 complex 20 kDa subunit (ARPC4) Sdh_cyt PF01127.22 CDJ86896.1 - 7.2e-22 77.7 3.0 1.8e-21 76.4 3.0 1.6 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Bcl-2 PF00452.19 CDJ86896.1 - 9.6e-13 48.7 0.1 2.2e-12 47.5 0.1 1.6 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family BH4 PF02180.17 CDJ86896.1 - 2.5e-06 27.2 0.0 6.6e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Bcl-2 homology region 4 DRY_EERY PF09750.9 CDJ86899.1 - 7.3e-42 142.8 0.9 7.3e-42 142.8 0.9 2.4 3 0 0 3 3 3 1 Alternative splicing regulator E2F_TDP PF02319.20 CDJ86901.1 - 1.7e-23 82.5 0.1 4.2e-23 81.2 0.1 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 CDJ86901.1 - 3.5e-19 69.0 0.0 6.9e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain IL11 PF07400.11 CDJ86901.1 - 0.03 14.0 0.1 0.053 13.2 0.1 1.3 1 0 0 1 1 1 0 Interleukin 11 HYLS1_C PF15311.6 CDJ86902.1 - 1.8e-11 44.6 0.3 4.7e-11 43.3 0.3 1.7 1 0 0 1 1 1 1 Hydrolethalus syndrome protein 1 C-terminus Rad60-SLD PF11976.8 CDJ86904.1 - 0.0045 16.8 0.0 0.007 16.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like BTB PF00651.31 CDJ86907.1 - 3.7e-26 91.5 0.1 6.8e-26 90.7 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 CDJ86907.1 - 7.9e-22 77.3 0.7 1.8e-21 76.1 0.7 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 CDJ86907.1 - 6.9e-16 57.6 1.2 1.7e-09 37.1 0.3 2.8 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 CDJ86907.1 - 4e-08 33.3 1.5 7.5e-05 22.9 0.1 2.8 1 1 2 3 3 3 2 Kelch motif Kelch_3 PF13415.6 CDJ86907.1 - 0.00011 22.4 0.2 0.0018 18.5 0.0 2.6 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.15 CDJ86907.1 - 0.00049 20.0 0.4 0.023 14.7 0.1 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.6 CDJ86907.1 - 0.014 15.4 0.1 0.1 12.6 0.0 2.4 2 1 1 3 3 3 0 Galactose oxidase, central domain PQQ_3 PF13570.6 CDJ86907.1 - 0.039 14.4 0.4 3.4 8.3 0.0 2.8 3 0 0 3 3 3 0 PQQ-like domain Kelch_5 PF13854.6 CDJ86907.1 - 0.14 12.2 0.1 14 5.8 0.0 2.5 2 0 0 2 2 2 0 Kelch motif BTB PF00651.31 CDJ86908.1 - 4.7e-26 91.2 0.2 7.7e-26 90.5 0.2 1.3 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.25 CDJ86908.1 - 6.1e-17 60.9 4.6 3.7e-08 32.8 0.4 3.4 3 0 0 3 3 3 3 Kelch motif BACK PF07707.15 CDJ86908.1 - 4.5e-15 55.6 0.0 9.1e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 CDJ86908.1 - 0.00012 22.1 0.1 0.00073 19.5 0.0 2.2 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.6 CDJ86908.1 - 0.00019 21.6 2.2 0.044 14.1 0.1 3.3 1 1 2 3 3 3 1 Kelch motif Kelch_3 PF13415.6 CDJ86908.1 - 0.0055 17.0 0.3 0.045 14.0 0.0 2.6 3 0 0 3 3 3 1 Galactose oxidase, central domain DEK_C PF08766.11 CDJ86908.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 DEK C terminal domain PQQ_3 PF13570.6 CDJ86908.1 - 0.24 11.9 2.2 9.5 6.9 0.2 3.1 3 0 0 3 3 3 0 PQQ-like domain VWA PF00092.28 CDJ86909.1 - 3.9e-56 190.0 0.1 3.6e-30 105.5 0.1 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 CDJ86909.1 - 5.8e-26 91.2 0.3 4.5e-12 46.6 0.0 2.6 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_CoxE PF05762.14 CDJ86909.1 - 2.2e-09 37.0 0.2 0.00041 19.8 0.0 2.4 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein DUF1194 PF06707.11 CDJ86909.1 - 2.1e-07 30.4 0.8 0.0041 16.4 0.8 3.0 2 2 0 2 2 2 2 Protein of unknown function (DUF1194) vWA-TerF-like PF10138.9 CDJ86909.1 - 3.1e-05 24.2 0.1 0.02 15.0 0.0 3.0 2 1 0 2 2 2 2 vWA found in TerF C terminus VWA_3 PF13768.6 CDJ86909.1 - 5.4e-05 23.2 0.0 0.054 13.4 0.0 3.3 3 1 1 4 4 4 1 von Willebrand factor type A domain Tir_receptor_C PF07489.11 CDJ86909.1 - 0.031 14.3 3.7 0.052 13.5 3.7 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus DUF501 PF04417.12 CDJ86909.1 - 0.093 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF501) Mucin PF01456.17 CDJ86909.1 - 0.82 9.7 18.6 1.6 8.7 18.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.12 CDJ86909.1 - 1.2 7.0 7.8 1.7 6.5 7.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Phostensin_N PF13916.6 CDJ86910.1 - 0.023 15.1 0.3 0.025 14.9 0.3 1.1 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal ShK PF01549.24 CDJ86911.1 - 7.3e-05 23.2 2.2 7.3e-05 23.2 2.2 3.1 2 1 0 2 2 2 1 ShK domain-like Astacin PF01400.24 CDJ86912.1 - 3.5e-28 98.5 0.5 4.1e-28 98.3 0.5 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Astacin PF01400.24 CDJ86914.1 - 1.7e-34 119.1 0.0 2.5e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Rap_GAP PF02145.15 CDJ86914.1 - 0.0019 17.8 0.1 0.0028 17.3 0.1 1.2 1 0 0 1 1 1 1 Rap/ran-GAP Astacin PF01400.24 CDJ86915.1 - 1.5e-33 116.0 0.0 2.4e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Gal_Lectin PF02140.18 CDJ86916.1 - 9.5e-23 80.4 2.4 2.2e-18 66.4 0.6 2.3 2 0 0 2 2 2 2 Galactose binding lectin domain Yeast-kill-tox PF09207.11 CDJ86916.1 - 0.011 16.3 0.3 0.047 14.3 0.0 2.1 2 0 0 2 2 2 0 Yeast killer toxin Disintegrin PF00200.23 CDJ86916.1 - 1.9 9.3 6.8 0.9 10.4 3.8 2.0 2 0 0 2 2 2 0 Disintegrin 7tm_1 PF00001.21 CDJ86917.1 - 9.2e-39 133.3 22.8 9.2e-39 133.3 22.8 2.8 4 0 0 4 4 4 1 7 transmembrane receptor (rhodopsin family) CDP-OH_P_transf PF01066.21 CDJ86917.1 - 6.3e-11 42.9 0.1 6.3e-11 42.9 0.1 5.2 4 3 0 4 4 4 1 CDP-alcohol phosphatidyltransferase Motile_Sperm PF00635.26 CDJ86918.1 - 4.1e-17 62.0 1.1 4.1e-17 62.0 1.1 2.5 2 1 0 2 2 1 1 MSP (Major sperm protein) domain Coilin_N PF15862.5 CDJ86918.1 - 0.0071 16.2 20.0 0.0097 15.7 20.0 1.4 1 1 0 1 1 1 1 Coilin N-terminus FixG_C PF11614.8 CDJ86918.1 - 0.0076 16.5 0.0 0.0076 16.5 0.0 1.7 2 1 0 2 2 1 1 IG-like fold at C-terminal of FixG, putative oxidoreductase RR_TM4-6 PF06459.12 CDJ86918.1 - 0.0096 15.8 19.3 0.0095 15.8 19.3 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 CobT PF06213.12 CDJ86918.1 - 0.013 14.9 18.7 0.017 14.5 18.5 1.3 1 1 0 1 1 1 0 Cobalamin biosynthesis protein CobT RNA_pol_Rpc4 PF05132.14 CDJ86918.1 - 0.026 15.0 12.6 0.029 14.8 12.6 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 CDC45 PF02724.14 CDJ86918.1 - 0.027 12.8 14.3 0.027 12.8 14.3 1.0 1 0 0 1 1 1 0 CDC45-like protein PapD_N PF00345.20 CDJ86918.1 - 0.028 14.3 0.0 0.028 14.3 0.0 2.0 2 1 0 2 2 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain SLC12 PF03522.15 CDJ86918.1 - 0.096 11.7 7.0 0.09 11.8 7.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DDHD PF02862.17 CDJ86918.1 - 0.1 12.8 5.1 0.1 12.7 5.1 1.2 1 0 0 1 1 1 0 DDHD domain AAA_11 PF13086.6 CDJ86918.1 - 0.11 12.2 9.8 0.13 12.1 9.8 1.1 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 CDJ86918.1 - 0.16 10.7 10.2 0.15 10.8 10.2 1.1 1 0 0 1 1 1 0 Presenilin U1snRNP70_N PF12220.8 CDJ86918.1 - 0.22 12.2 35.1 4e+02 1.7 35.1 3.0 1 1 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Vfa1 PF08432.10 CDJ86918.1 - 0.25 11.7 23.9 0.29 11.4 23.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DNA_pol_phi PF04931.13 CDJ86918.1 - 0.27 9.3 22.5 0.31 9.1 22.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi PBP_sp32 PF07222.12 CDJ86918.1 - 0.29 10.6 17.6 0.32 10.4 17.6 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF913 PF06025.12 CDJ86918.1 - 0.32 9.9 10.3 0.35 9.8 10.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SID-1_RNA_chan PF13965.6 CDJ86918.1 - 0.4 9.0 2.4 0.36 9.2 2.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF5308 PF17233.2 CDJ86918.1 - 0.6 10.3 2.9 0.59 10.3 2.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) EOS1 PF12326.8 CDJ86918.1 - 0.64 9.9 2.6 0.65 9.9 2.6 1.2 1 0 0 1 1 1 0 N-glycosylation protein Neur_chan_memb PF02932.16 CDJ86918.1 - 0.77 9.8 5.2 0.73 9.8 5.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CPSF100_C PF13299.6 CDJ86918.1 - 1.4 9.1 16.3 1.9 8.7 16.3 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PTPRCAP PF15713.5 CDJ86918.1 - 1.7 8.9 20.6 2 8.7 20.6 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Folate_carrier PF01770.18 CDJ86918.1 - 2.1 7.0 4.8 2 7.1 4.8 1.2 1 0 0 1 1 1 0 Reduced folate carrier Serinc PF03348.15 CDJ86918.1 - 2.9 6.7 6.0 2.8 6.8 6.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Roughex PF06020.11 CDJ86918.1 - 4.9 6.1 12.1 5.4 6.0 12.1 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Paf1 PF03985.13 CDJ86918.1 - 5.5 5.9 31.6 6.8 5.6 31.6 1.1 1 0 0 1 1 1 0 Paf1 DUF4820 PF16091.5 CDJ86918.1 - 7.1 5.9 12.3 8.5 5.7 12.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Peroxin-13_N PF04088.13 CDJ86918.1 - 7.6 6.8 5.8 9.9 6.4 5.8 1.4 1 0 0 1 1 1 0 Peroxin 13, N-terminal region RPN2_C PF18004.1 CDJ86918.1 - 8.2 6.3 31.6 15 5.5 31.6 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain NPR3 PF03666.13 CDJ86918.1 - 8.9 5.0 17.2 10 4.8 17.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pannexin_like PF12534.8 CDJ86918.1 - 9.2 5.2 7.2 10 5.1 7.2 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Pkinase PF00069.25 CDJ86920.1 - 1.6e-30 106.4 0.0 4.6e-30 104.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ86920.1 - 1.7e-18 66.9 0.0 4.1e-18 65.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase I-set PF07679.16 CDJ86920.1 - 9.6e-13 48.0 0.0 6e-10 39.1 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ86920.1 - 2e-09 37.9 0.0 8e-07 29.6 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 CDJ86920.1 - 0.00025 21.3 0.0 0.0052 17.1 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain APH PF01636.23 CDJ86920.1 - 0.0032 17.4 0.4 0.011 15.7 0.3 1.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family fn3 PF00041.21 CDJ86920.1 - 0.0033 17.7 0.0 0.017 15.5 0.0 2.0 2 0 0 2 2 2 1 Fibronectin type III domain ig PF00047.25 CDJ86920.1 - 0.082 13.1 0.0 2.1 8.6 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain RIO1 PF01163.22 CDJ86920.1 - 0.092 12.3 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 RIO1 family RhoGEF PF00621.20 CDJ86922.1 - 1.7e-29 103.4 1.9 1.7e-29 103.4 1.9 4.4 3 1 1 4 4 4 1 RhoGEF domain Spectrin PF00435.21 CDJ86922.1 - 8.6e-19 68.0 32.3 0.00023 21.6 0.3 9.2 7 2 1 8 8 8 5 Spectrin repeat CRAL_TRIO PF00650.20 CDJ86922.1 - 0.00029 20.6 0.0 0.023 14.4 0.0 2.6 2 0 0 2 2 2 1 CRAL/TRIO domain DUF496 PF04363.12 CDJ86922.1 - 0.012 15.6 4.2 0.03 14.3 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF496) IQ_SEC7_PH PF16453.5 CDJ86922.1 - 0.015 15.2 0.3 0.16 12.0 0.0 2.9 3 0 0 3 3 3 0 PH domain CRAL_TRIO_2 PF13716.6 CDJ86922.1 - 0.09 12.9 0.0 0.49 10.6 0.0 2.4 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain EcoEI_R_C PF08463.10 CDJ86922.1 - 0.13 12.4 1.6 0.61 10.2 0.1 3.0 3 0 0 3 3 3 0 EcoEI R protein C-terminal YkyA PF10368.9 CDJ86922.1 - 0.31 10.7 4.3 2.9 7.5 0.0 3.7 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein ubiquitin PF00240.23 CDJ86923.1 - 7e-28 96.2 0.1 7.7e-28 96.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CDJ86923.1 - 4.8e-15 55.1 0.2 5.2e-15 55.0 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDJ86923.1 - 4.2e-05 23.9 0.0 0.00013 22.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CDJ86923.1 - 0.00059 19.7 0.0 0.00068 19.5 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDJ86923.1 - 0.049 13.7 0.1 0.14 12.2 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like SRCR PF00530.18 CDJ86925.1 - 1.6e-17 63.8 0.9 3.8e-17 62.6 0.9 1.6 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Beta_helix PF13229.6 CDJ86925.1 - 1.7e-08 34.5 37.6 0.2 11.5 0.2 6.2 4 1 0 4 4 4 3 Right handed beta helix region MAP17 PF15807.5 CDJ86925.1 - 1.9e-05 24.9 0.0 3.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 SRCR_2 PF15494.6 CDJ86925.1 - 0.00055 20.4 0.4 0.00055 20.4 0.4 2.5 2 1 0 2 2 2 1 Scavenger receptor cysteine-rich domain Lectin_C PF00059.21 CDJ86925.1 - 0.0099 16.6 0.0 0.026 15.2 0.0 1.8 1 0 0 1 1 1 1 Lectin C-type domain Hepsin-SRCR PF09272.10 CDJ86925.1 - 0.01 16.4 0.1 0.028 14.9 0.1 1.7 1 0 0 1 1 1 0 Hepsin, SRCR domain TMEM51 PF15345.6 CDJ86925.1 - 0.011 15.6 0.5 0.026 14.4 0.2 1.7 1 1 0 1 1 1 0 Transmembrane protein 51 CYYR1 PF10873.8 CDJ86925.1 - 0.012 16.0 0.0 0.043 14.3 0.0 1.9 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 FixS PF03597.15 CDJ86925.1 - 0.72 9.6 4.9 1.4 8.7 4.9 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type HlyIII PF03006.20 CDJ86926.1 - 2.5e-70 236.7 21.6 3.1e-70 236.4 21.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related AARP2CN PF08142.12 CDJ86927.1 - 0.016 15.3 0.1 0.031 14.4 0.1 1.5 1 0 0 1 1 1 0 AARP2CN (NUC121) domain RVT_1 PF00078.27 CDJ86928.1 - 2.3e-12 46.9 0.0 2.7e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CAP_N PF01213.19 CDJ86929.1 - 0.13 11.8 3.8 2.2 7.7 2.6 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Peptidase_M13 PF01431.21 CDJ86930.1 - 1.9e-149 494.6 0.6 8.6e-74 247.6 0.0 2.9 3 0 0 3 3 3 2 Peptidase family M13 Peptidase_M13_N PF05649.13 CDJ86930.1 - 1.2e-105 354.4 12.2 5e-53 181.2 5.7 2.3 2 0 0 2 2 2 2 Peptidase family M13 Peptidase_M4 PF01447.18 CDJ86930.1 - 0.22 12.0 2.1 31 5.0 0.2 3.3 2 0 0 2 2 2 0 Thermolysin metallopeptidase, catalytic domain YvfG PF09628.10 CDJ86930.1 - 0.46 10.9 2.8 4.2 7.8 0.4 3.0 2 0 0 2 2 2 0 YvfG protein RVT_1 PF00078.27 CDJ86932.1 - 4e-19 69.0 0.0 7.5e-19 68.1 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDJ86932.1 - 1e-18 67.2 0.0 2.3e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ86932.1 - 2.7e-09 37.3 0.0 6e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 CDJ86932.1 - 1.5e-07 31.9 0.0 3.2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ86932.1 - 3.9e-07 30.6 0.0 8.4e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ86932.1 - 0.0016 18.8 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 CDJ86933.1 - 6.2e-21 74.8 0.0 9.6e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ86933.1 - 4.6e-12 45.9 0.2 1e-11 44.8 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CDJ86933.1 - 3e-05 23.7 0.0 5.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Ank_2 PF12796.7 CDJ86934.1 - 4.9e-17 62.3 0.4 3.9e-06 27.4 0.1 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ86934.1 - 2.4e-16 59.9 0.8 0.0021 18.6 0.1 4.3 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ86934.1 - 8.3e-15 54.7 2.5 6.8e-05 23.1 0.0 3.8 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CDJ86934.1 - 1.2e-14 54.0 0.7 0.1 13.1 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 CDJ86934.1 - 5.1e-12 44.9 1.1 0.03 14.8 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat DivIC PF04977.15 CDJ86935.1 - 0.0031 17.2 0.1 0.024 14.4 0.0 2.2 2 0 0 2 2 2 1 Septum formation initiator hEGF PF12661.7 CDJ86936.1 - 1.6e-06 28.5 17.0 6.3e-05 23.5 2.1 9.0 7 3 1 8 8 8 4 Human growth factor-like EGF Laminin_EGF PF00053.24 CDJ86936.1 - 2.3e-06 27.6 86.9 0.0069 16.5 16.9 6.0 1 1 4 5 5 5 2 Laminin EGF domain EGF_2 PF07974.13 CDJ86936.1 - 3.1e-06 27.4 96.8 0.0023 18.3 11.6 8.9 7 2 2 9 9 9 4 EGF-like domain EGF PF00008.27 CDJ86936.1 - 0.019 15.3 9.6 0.019 15.3 9.6 8.3 8 1 0 8 8 8 0 EGF-like domain DSL PF01414.19 CDJ86936.1 - 0.11 12.8 90.3 0.059 13.7 13.6 5.4 5 0 0 5 5 5 0 Delta serrate ligand zf-RRN7 PF11781.8 CDJ86937.1 - 0.00055 19.6 0.6 0.00055 19.6 0.6 2.1 2 0 0 2 2 2 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 OrfB_Zn_ribbon PF07282.11 CDJ86937.1 - 0.0027 17.6 1.0 0.0064 16.4 1.0 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain FlaF PF07309.11 CDJ86937.1 - 0.13 12.3 0.4 0.28 11.2 0.4 1.5 1 0 0 1 1 1 0 Flagellar protein FlaF Auto_anti-p27 PF06677.12 CDJ86937.1 - 0.19 11.9 1.6 2.8 8.2 1.5 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TF_Zn_Ribbon PF08271.12 CDJ86937.1 - 0.21 11.2 2.2 0.42 10.2 2.2 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding zf-RRPl_C4 PF17026.5 CDJ86937.1 - 2.2 8.4 5.5 0.66 10.1 0.1 2.8 4 0 0 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type Collagen PF01391.18 CDJ86938.1 - 1.1e-13 50.7 39.9 1.1e-07 31.5 39.9 2.5 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Collagen PF01391.18 CDJ86939.1 - 1.2e-24 85.8 73.2 1.6e-10 40.6 22.9 3.9 2 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ86939.1 - 0.0072 16.4 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Med16 PF11635.8 CDJ86939.1 - 0.046 11.6 0.1 0.061 11.2 0.1 1.0 1 0 0 1 1 1 0 Mediator complex subunit 16 Neur_chan_LBD PF02931.23 CDJ86940.1 - 4.7e-58 196.2 0.1 6.6e-58 195.7 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ86940.1 - 1.3e-54 185.8 0.5 1.7e-54 185.4 0.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Pkinase PF00069.25 CDJ86941.1 - 3.6e-11 42.9 0.0 4.3e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ86941.1 - 0.00042 19.7 0.0 0.00048 19.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ86941.1 - 0.023 14.6 0.2 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family EB PF01683.18 CDJ86942.1 - 6.1e-19 68.1 63.1 7.2e-09 35.8 8.2 4.9 3 1 3 6 6 6 4 EB module Lustrin_cystein PF14625.6 CDJ86942.1 - 0.0034 17.7 8.5 0.0034 17.7 8.5 5.2 5 1 0 5 5 5 1 Lustrin, cysteine-rich repeated domain DUF5346 PF17281.2 CDJ86942.1 - 0.025 14.6 1.7 0.025 14.6 1.7 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5346) AA_permease PF00324.21 CDJ86943.1 - 8.1e-52 176.4 33.2 5.1e-38 130.9 7.5 2.1 2 0 0 2 2 2 2 Amino acid permease SLC12 PF03522.15 CDJ86943.1 - 6.4e-38 130.9 8.1 2.8e-14 53.0 2.9 3.3 1 1 1 3 3 3 3 Solute carrier family 12 Rhodanese PF00581.20 CDJ86944.1 - 5.2e-25 88.0 0.0 2.8e-17 63.2 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain RhoGAP PF00620.27 CDJ86945.1 - 4.5e-23 81.8 0.0 6.5e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain HELP PF03451.14 CDJ86946.1 - 6.3e-18 64.4 0.1 1.2e-17 63.5 0.1 1.5 1 0 0 1 1 1 1 HELP motif WD40 PF00400.32 CDJ86946.1 - 1.6e-13 50.9 9.6 0.0015 19.3 0.2 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ86946.1 - 1.6e-05 25.1 0.1 0.016 15.5 0.0 4.3 2 2 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 CDJ86946.1 - 0.0012 18.9 0.0 0.016 15.2 0.0 2.7 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Mcl1_mid PF12341.8 CDJ86946.1 - 0.0026 17.2 0.2 0.11 11.8 0.0 2.9 3 1 0 3 3 3 1 Minichromosome loss protein, Mcl1, middle region Fib_alpha PF08702.10 CDJ86946.1 - 0.0086 16.3 0.3 0.02 15.1 0.3 1.5 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family WD40_like PF17005.5 CDJ86946.1 - 0.056 12.8 0.3 0.31 10.3 0.0 2.1 2 1 0 2 2 2 0 WD40-like domain KASH_CCD PF14662.6 CDJ86946.1 - 0.083 12.7 0.7 0.14 11.9 0.7 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH EGF_Tenascin PF18720.1 CDJ86946.1 - 4.7 7.4 5.9 0.72 10.0 0.8 2.4 2 0 0 2 2 2 0 Tenascin EGF domain FAD_binding_3 PF01494.19 CDJ86947.1 - 1.8e-18 66.9 0.0 3.4e-15 56.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 CDJ86947.1 - 4.9e-07 29.1 0.0 0.02 13.9 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase NAD_binding_8 PF13450.6 CDJ86947.1 - 0.0084 16.3 0.2 0.036 14.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CDJ86947.1 - 0.022 14.3 0.1 0.32 10.5 0.0 2.1 1 1 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 CDJ86947.1 - 0.044 13.7 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 CDJ86947.1 - 0.051 14.1 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CDJ86947.1 - 0.081 12.2 0.0 0.15 11.3 0.0 1.4 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 CDJ86947.1 - 0.084 12.5 0.0 0.22 11.2 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ApoO PF09769.9 CDJ86948.1 - 3.1e-17 62.8 0.0 4.2e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Apolipoprotein O DUF4618 PF15397.6 CDJ86948.1 - 0.06 12.8 0.1 0.084 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF883 PF05957.13 CDJ86948.1 - 0.13 12.9 0.0 0.26 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Iso_dh PF00180.20 CDJ86949.1 - 4.3e-74 249.7 0.0 5.5e-74 249.4 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4116 PF13475.6 CDJ86950.1 - 0.13 12.0 0.0 0.34 10.7 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4116) UNC80 PF15778.5 CDJ86951.1 - 2.1e-27 95.9 0.0 4e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 Cation channel complex component UNC80 SAM_1 PF00536.30 CDJ86952.1 - 2.3e-19 69.6 0.2 3.7e-19 68.9 0.2 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CDJ86952.1 - 7.7e-16 58.0 0.1 1.3e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 CDJ86952.1 - 0.0047 17.1 0.0 0.012 15.8 0.0 1.7 2 0 0 2 2 2 1 Ste50p, sterile alpha motif SAM_PNT PF02198.16 CDJ86952.1 - 0.0047 16.9 0.1 0.0089 16.0 0.1 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 CDJ86952.1 - 0.0051 16.6 0.0 0.0094 15.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) YjbE PF11106.8 CDJ86953.1 - 0.1 12.9 5.6 0.35 11.1 5.6 1.9 1 1 0 1 1 1 0 Exopolysaccharide production protein YjbE DUF5352 PF17303.2 CDJ86954.1 - 0.13 12.1 0.1 0.22 11.4 0.1 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5352) Myosin_head PF00063.21 CDJ86955.1 - 5e-09 35.0 2.1 6.6e-09 34.6 0.0 2.2 2 0 0 2 2 2 1 Myosin head (motor domain) Filament PF00038.21 CDJ86955.1 - 0.00074 19.2 114.3 0.019 14.5 7.0 6.4 2 1 4 6 6 6 4 Intermediate filament protein Myosin_tail_1 PF01576.19 CDJ86955.1 - 0.0012 16.7 129.2 0.0013 16.7 61.1 4.1 1 1 2 4 4 4 2 Myosin tail TPR_MLP1_2 PF07926.12 CDJ86955.1 - 0.013 15.5 31.1 0.013 15.5 31.1 7.7 1 1 4 7 7 7 0 TPR/MLP1/MLP2-like protein GST_C_2 PF13410.6 CDJ86955.1 - 0.29 11.2 1.7 12 6.0 0.1 3.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain FlaC_arch PF05377.11 CDJ86955.1 - 7.3 7.1 54.9 2.2 8.7 2.1 9.8 7 2 3 10 10 10 0 Flagella accessory protein C (FlaC) 3Beta_HSD PF01073.19 CDJ86956.1 - 0.0052 15.8 0.0 0.0064 15.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CDJ86956.1 - 0.0087 15.2 0.0 0.01 15.0 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain HEAT PF02985.22 CDJ86958.1 - 6.3e-40 131.8 38.5 0.00024 21.1 0.0 22.1 24 1 0 25 25 23 7 HEAT repeat HEAT_2 PF13646.6 CDJ86958.1 - 2.5e-26 91.9 49.9 2.2e-05 24.8 0.0 16.7 12 5 8 20 20 19 6 HEAT repeats CLASP_N PF12348.8 CDJ86958.1 - 1.7e-24 86.7 7.3 4e-05 23.3 0.0 8.2 7 1 2 9 9 9 6 CLASP N terminal Cnd1 PF12717.7 CDJ86958.1 - 1.9e-23 83.3 5.2 0.00014 21.9 0.0 10.6 9 2 2 11 11 10 4 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CDJ86958.1 - 2.1e-21 76.0 39.6 0.021 15.3 0.1 16.8 16 3 2 18 18 17 7 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CDJ86958.1 - 7.1e-18 65.0 0.0 0.051 14.2 0.0 8.9 6 3 1 8 8 7 4 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 CDJ86958.1 - 1.6e-15 56.7 16.3 0.0011 17.6 0.0 8.7 7 2 0 8 8 8 5 Adaptin N terminal region Ecm29 PF13001.7 CDJ86958.1 - 7.7e-15 54.5 1.9 4.3e-05 22.4 0.0 5.2 6 0 0 6 6 6 3 Proteasome stabiliser MMS19_C PF12460.8 CDJ86958.1 - 1.2e-06 28.0 23.2 0.011 14.8 0.1 7.6 7 1 1 8 8 8 4 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 CDJ86958.1 - 3e-06 27.3 0.0 4 7.3 0.0 6.7 7 0 0 7 7 6 1 Domain of unknown function (DUF3385) Tti2 PF10521.9 CDJ86958.1 - 1.2e-05 25.0 0.9 1.5 8.3 0.0 5.7 5 2 1 6 6 6 2 Tti2 family UME PF08064.13 CDJ86958.1 - 1.3e-05 25.0 0.3 2 8.4 0.0 6.8 7 1 0 7 7 7 1 UME (NUC010) domain RTP1_C1 PF10363.9 CDJ86958.1 - 5.1e-05 23.4 6.2 4.1 7.6 0.1 7.2 6 1 1 7 7 7 1 Required for nuclear transport of RNA pol II C-terminus 1 ParcG PF10274.9 CDJ86958.1 - 0.00072 19.7 4.7 0.2 11.7 0.0 5.9 7 0 0 7 7 7 1 Parkin co-regulated protein V-ATPase_H_N PF03224.14 CDJ86958.1 - 0.0012 18.2 2.3 2.2 7.5 0.0 5.5 5 0 0 5 5 5 1 V-ATPase subunit H MMS19_N PF14500.6 CDJ86958.1 - 0.0024 17.5 1.8 3.4 7.2 0.2 4.3 4 0 0 4 4 4 2 Dos2-interacting transcription regulator of RNA-Pol-II RIX1 PF08167.12 CDJ86958.1 - 0.0047 16.7 6.5 8 6.2 0.1 7.2 8 0 0 8 8 8 1 rRNA processing/ribosome biogenesis NUC173 PF08161.12 CDJ86958.1 - 0.01 15.5 3.4 0.61 9.7 0.1 4.6 3 1 1 4 4 4 0 NUC173 domain NopRA1 PF16201.5 CDJ86958.1 - 0.012 15.2 6.4 0.25 10.9 0.1 5.6 5 1 0 6 6 6 0 Nucleolar pre-ribosomal-associated protein 1 Dopey_N PF04118.14 CDJ86958.1 - 0.013 14.6 1.4 1.8 7.6 0.0 4.1 4 1 1 5 5 5 0 Dopey, N-terminal Arm PF00514.23 CDJ86958.1 - 0.036 14.1 6.9 98 3.2 0.0 7.6 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Condensin2nSMC PF12422.8 CDJ86958.1 - 0.92 9.7 4.5 69 3.6 0.0 5.5 6 1 0 6 6 4 0 Condensin II non structural maintenance of chromosomes subunit GatB_N PF02934.15 CDJ86959.1 - 4.8e-101 337.7 0.0 6.4e-101 337.3 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 CDJ86959.1 - 4.7e-12 46.0 0.6 7e-12 45.5 0.6 1.2 1 0 0 1 1 1 1 GatB domain ShK PF01549.24 CDJ86960.1 - 0.00052 20.5 5.5 0.00081 19.9 5.5 1.4 1 0 0 1 1 1 1 ShK domain-like ORC6 PF05460.13 CDJ86961.1 - 0.085 12.1 6.0 0.11 11.8 6.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) 7TM_GPCR_Srx PF10328.9 CDJ86962.1 - 7.4e-09 35.6 0.4 8.6e-09 35.4 0.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srt PF10321.9 CDJ86962.1 - 0.00098 18.2 0.0 0.0011 18.0 0.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt DUF4199 PF13858.6 CDJ86963.1 - 0.0064 16.9 0.2 1.6 9.1 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF4199) Copper-fist PF00649.18 CDJ86963.1 - 0.12 11.9 0.3 0.25 10.9 0.3 1.5 1 0 0 1 1 1 0 Copper fist DNA binding domain DnaJ PF00226.31 CDJ86964.1 - 2e-12 47.0 1.2 2e-12 47.0 1.2 1.8 2 0 0 2 2 2 1 DnaJ domain Yip1 PF04893.17 CDJ86965.1 - 0.0037 17.0 6.2 0.0081 15.9 6.2 1.5 1 0 0 1 1 1 1 Yip1 domain FA_desaturase PF00487.24 CDJ86965.1 - 0.052 13.4 2.4 0.068 13.0 2.4 1.1 1 0 0 1 1 1 0 Fatty acid desaturase LapA_dom PF06305.11 CDJ86965.1 - 1.8 8.4 10.2 0.62 9.9 0.3 2.7 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Pox_Ag35 PF03286.14 CDJ86966.1 - 0.022 14.6 0.3 0.028 14.2 0.3 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF818 PF05677.12 CDJ86966.1 - 0.097 11.6 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) CCD48 PF15799.5 CDJ86966.1 - 0.13 10.6 0.4 0.15 10.3 0.4 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 SNAD3 PF18749.1 CDJ86967.1 - 0.007 15.6 0.3 0.0095 15.1 0.3 1.1 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 3 Vip3A_N PF12495.8 CDJ86967.1 - 0.035 14.0 0.1 0.047 13.6 0.1 1.2 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal DUF948 PF06103.11 CDJ86967.1 - 0.04 14.2 0.1 0.067 13.5 0.1 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) RNase_P_Rpp14 PF01900.19 CDJ86967.1 - 0.079 13.2 0.1 0.18 12.1 0.0 1.5 1 1 0 1 1 1 0 Rpp14/Pop5 family COX14 PF14880.6 CDJ86967.1 - 0.42 10.5 2.6 7.1 6.6 0.3 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c assembly SBP PF03110.14 CDJ86968.1 - 0.016 15.5 0.7 0.016 15.5 0.7 2.1 2 0 0 2 2 2 0 SBP domain zf-UBR PF02207.20 CDJ86968.1 - 9.8 6.4 15.3 0.62 10.3 8.8 2.4 2 1 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Glyco_hydro_38C PF07748.13 CDJ86971.1 - 2.8e-18 66.8 0.0 4e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain HlyIII PF03006.20 CDJ86972.1 - 4.9e-60 203.0 17.2 5.6e-60 202.8 17.2 1.0 1 0 0 1 1 1 1 Haemolysin-III related AAA PF00004.29 CDJ86973.1 - 1.4e-38 132.3 0.0 3.5e-38 131.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDJ86973.1 - 1e-06 28.8 0.1 8.1e-06 25.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 CDJ86973.1 - 3.8e-06 26.6 0.2 3.8e-06 26.6 0.2 2.4 2 1 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 CDJ86973.1 - 1e-05 26.0 2.4 0.00068 20.1 0.1 2.8 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CDJ86973.1 - 1.5e-05 25.3 0.2 0.0021 18.4 0.0 2.7 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 CDJ86973.1 - 2.8e-05 23.9 0.0 4.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CDJ86973.1 - 7.1e-05 23.0 0.1 0.0018 18.5 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CDJ86973.1 - 0.00011 22.2 0.0 0.00025 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CDJ86973.1 - 0.00023 21.3 0.0 0.0005 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TniB PF05621.11 CDJ86973.1 - 0.00027 20.4 0.2 0.14 11.5 0.0 3.0 2 1 1 3 3 3 1 Bacterial TniB protein AAA_18 PF13238.6 CDJ86973.1 - 0.00056 20.5 0.0 0.0013 19.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CDJ86973.1 - 0.0012 19.2 0.0 0.0027 18.1 0.0 1.8 1 1 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 CDJ86973.1 - 0.0014 18.4 0.0 0.004 16.9 0.0 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 CDJ86973.1 - 0.0021 17.9 0.0 0.005 16.7 0.0 1.6 2 0 0 2 2 1 1 Bacterial dnaA protein AAA_25 PF13481.6 CDJ86973.1 - 0.0038 16.8 0.7 0.19 11.3 0.1 2.6 1 1 1 2 2 2 1 AAA domain NACHT PF05729.12 CDJ86973.1 - 0.0038 17.1 0.2 0.064 13.2 0.0 2.3 1 1 1 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 CDJ86973.1 - 0.0044 16.4 0.1 0.013 14.9 0.1 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 CDJ86973.1 - 0.0057 15.8 0.0 0.0093 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 CDJ86973.1 - 0.0057 16.4 0.1 0.016 15.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CDJ86973.1 - 0.0075 16.8 0.0 0.3 11.6 0.0 2.6 2 1 0 2 2 2 1 ABC transporter Rad17 PF03215.15 CDJ86973.1 - 0.018 15.0 0.0 0.049 13.5 0.0 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain TsaE PF02367.17 CDJ86973.1 - 0.027 14.4 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 CDJ86973.1 - 0.029 14.5 0.0 0.067 13.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 CDJ86973.1 - 0.03 14.2 0.0 0.051 13.4 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CDJ86973.1 - 0.03 14.6 0.0 0.08 13.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain TIP49 PF06068.13 CDJ86973.1 - 0.035 13.3 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain SKI PF01202.22 CDJ86973.1 - 0.052 13.7 0.1 0.23 11.6 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase AAA_21 PF13304.6 CDJ86973.1 - 0.054 13.3 0.1 9.9 5.9 0.0 2.4 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ATPase PF06745.13 CDJ86973.1 - 0.065 12.6 0.1 1.5 8.1 0.0 2.3 1 1 0 2 2 2 0 KaiC ATPase_2 PF01637.18 CDJ86973.1 - 0.071 13.0 0.1 0.36 10.7 0.0 2.0 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Glyco_hydro_3_C PF01915.22 CDJ86973.1 - 0.1 12.5 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain AAA_17 PF13207.6 CDJ86973.1 - 0.11 13.0 0.0 0.36 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain tRNA_lig_kinase PF08303.11 CDJ86973.1 - 0.13 12.3 0.0 0.62 10.1 0.0 2.0 2 0 0 2 2 2 0 tRNA ligase kinase domain Parvo_NS1 PF01057.17 CDJ86973.1 - 0.16 11.0 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 WD40 PF00400.32 CDJ86974.1 - 3.6e-32 109.9 15.6 2.2e-08 34.6 0.1 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ86974.1 - 1.1e-08 35.2 0.6 0.06 13.7 0.0 3.7 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDJ86974.1 - 0.00013 21.9 0.1 0.4 10.5 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CDJ86974.1 - 0.00086 18.7 0.0 0.035 13.4 0.0 2.1 2 0 0 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 CDJ86974.1 - 0.0011 18.1 0.1 5.6 5.8 0.0 3.1 3 0 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CDJ86974.1 - 0.015 15.2 0.0 9.2 6.3 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat cNMP_binding PF00027.29 CDJ86975.1 - 4.5e-08 33.0 0.0 0.008 16.2 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RasGEF_N PF00618.20 CDJ86975.1 - 6.4e-07 29.6 0.0 1.2e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 RasGEF N-terminal motif Cupin_2 PF07883.11 CDJ86975.1 - 0.055 13.2 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Cupin domain 7tm_1 PF00001.21 CDJ86976.1 - 1e-19 70.9 8.4 1.5e-19 70.4 8.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ86976.1 - 3.6e-06 26.6 7.7 5e-06 26.1 7.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Mit_KHE1 PF10173.9 CDJ86976.1 - 0.0034 17.5 0.5 0.0066 16.6 0.5 1.4 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Orthoreo_P10 PF07204.11 CDJ86976.1 - 0.096 12.6 0.1 0.34 10.9 0.1 1.9 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Ecotin PF03974.13 CDJ86976.1 - 0.15 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Ecotin SecY PF00344.20 CDJ86976.1 - 0.2 10.9 0.9 0.25 10.6 0.9 1.1 1 0 0 1 1 1 0 SecY translocase RVT_1 PF00078.27 CDJ86977.1 - 2.6e-08 33.7 0.0 2.7e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_1 PF00001.21 CDJ86978.1 - 6.9e-16 58.4 4.6 7.9e-16 58.2 4.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2834 PF11196.8 CDJ86978.1 - 0.0076 16.6 1.2 0.012 15.9 1.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2834) gag-asp_proteas PF13975.6 CDJ86979.1 - 0.00012 22.6 0.0 0.00028 21.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease LBP_BPI_CETP_C PF02886.17 CDJ86980.1 - 3.1e-05 23.5 0.0 4.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 CDJ86981.1 - 3.7e-06 26.6 0.0 5.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain C2 PF00168.30 CDJ86982.1 - 4.2e-15 55.9 0.1 5.6e-15 55.5 0.1 1.2 1 0 0 1 1 1 1 C2 domain C1_1 PF00130.22 CDJ86982.1 - 9.8e-06 25.4 4.1 1.4e-05 24.9 4.1 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 CDJ86982.1 - 0.15 11.9 2.5 0.24 11.3 2.5 1.4 1 0 0 1 1 1 0 PHD-finger DDE_Tnp_4 PF13359.6 CDJ86983.1 - 0.0055 16.4 0.0 0.0086 15.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 CDJ86983.1 - 0.033 13.8 0.0 0.04 13.5 0.0 1.1 1 0 0 1 1 1 0 Plant transposon protein Pkinase PF00069.25 CDJ86984.1 - 1.7e-33 116.1 0.0 3.7e-33 115.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ86984.1 - 5.1e-30 104.6 0.1 2.9e-28 98.8 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Activin_recp PF01064.23 CDJ86984.1 - 4.1e-09 37.4 13.4 1e-08 36.1 13.4 1.7 1 0 0 1 1 1 1 Activin types I and II receptor domain TGF_beta_GS PF08515.12 CDJ86984.1 - 1.3e-05 24.6 0.0 3.2e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Pkinase_fungal PF17667.1 CDJ86984.1 - 0.014 14.2 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Serglycin PF04360.12 CDJ86984.1 - 0.017 15.1 0.6 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Serglycin APH PF01636.23 CDJ86984.1 - 0.097 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4147 PF13660.6 CDJ86986.1 - 2.3e-38 132.0 0.2 3e-38 131.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 CDJ86986.1 - 2.9e-32 111.1 0.0 5.3e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 MOFRL family Adap_comp_sub PF00928.21 CDJ86987.1 - 1.4e-29 103.3 0.3 2e-29 102.8 0.3 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CDJ86987.1 - 5.6e-05 23.1 0.1 9.1e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF2207 PF09972.9 CDJ86987.1 - 0.024 13.4 0.0 0.046 12.5 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) bMG10 PF17973.1 CDJ86987.1 - 0.087 13.0 0.1 0.45 10.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial Alpha-2-macroglobulin MG10 domain Acetyltransf_1 PF00583.25 CDJ86988.1 - 1.6e-15 57.4 0.1 2e-15 57.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDJ86988.1 - 2.6e-08 33.9 0.0 3.4e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDJ86988.1 - 1.2e-07 32.0 0.0 1.8e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDJ86988.1 - 4.1e-05 23.5 0.0 7.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 CDJ86988.1 - 0.0063 17.2 0.0 0.0077 16.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CDJ86988.1 - 0.048 13.8 0.0 0.09 12.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 CDJ86988.1 - 0.12 12.4 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Orai-1 PF07856.12 CDJ86989.1 - 3.1e-48 163.8 6.8 4e-48 163.4 6.8 1.1 1 0 0 1 1 1 1 Mediator of CRAC channel activity DUF3007 PF11460.8 CDJ86989.1 - 0.037 14.3 0.4 0.08 13.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) Ctr PF04145.15 CDJ86992.1 - 3.1 8.4 4.1 1.7 9.2 1.0 2.1 2 0 0 2 2 2 0 Ctr copper transporter family Collagen PF01391.18 CDJ86993.1 - 5.9e-20 70.8 109.3 4.5e-06 26.3 41.6 4.3 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Lig_chan PF00060.26 CDJ86996.1 - 2.1e-54 183.4 0.3 3.3e-54 182.8 0.3 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 CDJ86996.1 - 2.8e-40 137.1 0.0 6e-40 136.0 0.0 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 CDJ86996.1 - 1.8e-19 70.1 0.0 4e-19 68.9 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 CDJ86996.1 - 2.3e-07 30.3 0.0 2.7e-05 23.5 0.0 2.4 1 1 1 2 2 2 2 Receptor family ligand binding region LapA_dom PF06305.11 CDJ86996.1 - 3.7 7.4 4.8 1.8 8.5 0.3 2.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain CLP1_P PF16575.5 CDJ86997.1 - 1.6e-69 233.4 0.0 2.5e-69 232.8 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 CDJ86997.1 - 2.3e-29 101.4 0.1 4.1e-29 100.6 0.1 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 CDJ86997.1 - 4e-24 85.3 0.1 6e-24 84.7 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 AAA_24 PF13479.6 CDJ86997.1 - 0.0012 18.7 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CDJ86997.1 - 0.0016 18.1 0.0 0.0096 15.6 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CbiA PF01656.23 CDJ86997.1 - 0.0088 16.1 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain PduV-EutP PF10662.9 CDJ86997.1 - 0.019 14.7 0.0 0.087 12.6 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 CDJ86997.1 - 0.027 14.9 0.0 0.047 14.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 CDJ86997.1 - 0.042 13.6 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 CDJ86997.1 - 0.089 12.9 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Roc PF08477.13 CDJ86997.1 - 0.093 13.0 0.0 0.29 11.3 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 CDJ86997.1 - 0.11 13.0 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.25 CDJ86998.1 - 1.2e-14 54.6 0.0 1.5e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDJ86998.1 - 1e-09 38.6 0.0 1.5e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDJ86998.1 - 1.1e-09 38.3 0.0 1.3e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDJ86998.1 - 9.5e-06 25.5 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 CDJ86998.1 - 0.0042 16.8 0.0 0.0048 16.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_4 PF13420.7 CDJ86998.1 - 0.0094 16.1 0.3 0.023 14.8 0.3 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CDJ86998.1 - 0.017 15.2 0.0 0.03 14.4 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CDJ86998.1 - 0.059 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acyl-CoA_dh_N PF02771.16 CDJ86999.1 - 2e-25 89.7 0.0 3e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CDJ86999.1 - 1.7e-22 79.4 0.0 3.1e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HpaB_N PF11794.8 CDJ86999.1 - 0.11 12.2 0.0 0.26 10.9 0.0 1.6 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF1657 PF07870.11 CDJ87001.1 - 0.058 13.3 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) DUF4668 PF15701.5 CDJ87001.1 - 0.11 12.3 3.6 0.39 10.5 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4668) DUF5400 PF17379.2 CDJ87003.1 - 0.7 10.4 5.5 0.086 13.3 1.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5400) PAN_1 PF00024.26 CDJ87004.1 - 2.5e-05 24.1 2.6 5.5e-05 23.1 0.5 2.3 2 0 0 2 2 2 1 PAN domain Eapp_C PF10238.9 CDJ87004.1 - 0.029 14.5 0.6 0.044 13.9 0.6 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein TSP_1 PF00090.19 CDJ87005.1 - 4.2e-13 49.3 7.9 1.2e-12 47.9 7.9 1.8 1 0 0 1 1 1 1 Thrombospondin type 1 domain DUF3976 PF13121.6 CDJ87005.1 - 6.7 6.9 6.4 2.1 8.5 3.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3976) ubiquitin PF00240.23 CDJ87006.1 - 2.1e-203 658.6 30.4 3.5e-33 113.2 0.4 6.0 6 0 0 6 6 6 6 Ubiquitin family Rad60-SLD PF11976.8 CDJ87006.1 - 5.2e-95 311.3 33.0 3.4e-15 55.6 0.5 6.0 6 0 0 6 6 6 6 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDJ87006.1 - 2.6e-34 117.5 15.7 0.0005 20.5 0.1 8.0 6 6 0 6 6 6 6 Ubiquitin-like domain Ubiquitin_5 PF18037.1 CDJ87006.1 - 5.3e-22 78.0 13.9 0.048 14.0 0.1 6.1 1 1 5 6 6 6 6 Ubiquitin-like domain TBK1_ULD PF18396.1 CDJ87006.1 - 1.2e-21 76.5 10.8 0.069 13.1 0.1 6.3 6 0 0 6 6 6 6 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDJ87006.1 - 2.7e-20 72.5 7.7 0.18 12.0 0.1 7.1 6 5 0 6 6 6 6 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CDJ87006.1 - 9e-19 68.0 3.7 0.44 11.1 0.1 6.2 1 1 2 6 6 6 6 DUF2407 ubiquitin-like domain Big_7 PF17957.1 CDJ87006.1 - 5.4e-15 55.9 0.1 5.5 7.8 0.0 6.2 6 0 0 6 6 6 6 Bacterial Ig domain DUF2870 PF11069.8 CDJ87006.1 - 8.3e-09 35.7 0.0 51 4.3 0.0 6.8 6 0 0 6 6 6 0 Protein of unknown function (DUF2870) UDP-g_GGTase PF06427.11 CDJ87006.1 - 4.8e-08 33.1 10.0 8.1 6.6 0.0 6.1 6 0 0 6 6 6 5 UDP-glucose:Glycoprotein Glucosyltransferase Big_3_3 PF13750.6 CDJ87006.1 - 1.8e-07 31.0 0.0 44 3.7 0.0 5.9 6 0 0 6 6 6 0 Bacterial Ig-like domain (group 3) Ubiquitin_4 PF18036.1 CDJ87006.1 - 2.2e-07 30.8 42.2 29 4.8 0.2 11.8 12 0 0 12 12 12 0 Ubiquitin-like domain DUF3861 PF12977.7 CDJ87006.1 - 5.9e-07 29.6 9.0 29 4.9 0.0 6.2 6 0 0 6 6 6 0 Domain of Unknown Function with PDB structure (DUF3861) DUF969 PF06149.12 CDJ87006.1 - 1.9e-06 27.5 0.3 39 3.6 0.0 5.8 6 0 0 6 6 6 0 Protein of unknown function (DUF969) ORF11CD3 PF10549.9 CDJ87006.1 - 5.6e-05 23.2 0.0 1.6e+02 2.5 0.0 6.5 6 0 0 6 6 6 0 ORF11CD3 domain PDGLE PF13190.6 CDJ87006.1 - 9e-05 22.3 14.1 28 4.7 0.1 6.8 1 1 2 6 6 6 0 PDGLE domain ACT_5 PF13710.6 CDJ87006.1 - 0.00046 20.0 9.0 65 3.5 0.1 6.2 6 0 0 6 6 6 0 ACT domain ACT_4 PF13291.6 CDJ87006.1 - 0.0011 19.5 4.2 2.3e+02 2.5 0.0 6.0 6 0 0 6 6 6 0 ACT domain Baculo_p48 PF04878.13 CDJ87006.1 - 0.033 13.1 0.0 1.7e+02 1.0 0.0 4.4 5 0 0 5 5 5 0 Baculovirus P48 protein ProRS-C_2 PF09181.10 CDJ87006.1 - 0.043 13.9 12.5 1.3e+02 2.8 0.1 6.0 6 0 0 6 6 6 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 CDJ87006.1 - 3.1 7.7 16.9 1.5e+02 2.3 0.1 6.1 6 0 0 6 6 6 0 FlgD Ig-like domain Nup96 PF12110.8 CDJ87007.1 - 8.5e-51 172.8 3.3 1.5e-50 172.0 3.3 1.4 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 CDJ87007.1 - 2.1e-42 144.7 0.0 3.6e-42 144.0 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 CDJ87007.1 - 2.5e-22 79.5 166.3 2.3e-05 25.2 24.4 7.0 2 2 4 6 6 6 5 Nucleoporin FG repeat region IATP PF04568.12 CDJ87008.1 - 2.7e-23 82.2 2.7 3.5e-23 81.9 2.7 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF5082 PF16888.5 CDJ87008.1 - 0.0069 16.7 2.2 0.0084 16.4 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) Fib_alpha PF08702.10 CDJ87008.1 - 0.013 15.6 3.8 0.016 15.4 3.8 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF5320 PF17253.2 CDJ87008.1 - 0.021 15.9 2.8 0.027 15.5 2.7 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5320) DUF4407 PF14362.6 CDJ87008.1 - 0.031 13.6 1.5 0.036 13.4 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SWI-SNF_Ssr4 PF08549.10 CDJ87008.1 - 0.047 12.3 4.1 0.055 12.1 4.1 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF1664 PF07889.12 CDJ87008.1 - 0.085 12.9 2.2 0.12 12.4 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) MbeB_N PF04837.12 CDJ87008.1 - 0.49 10.7 10.3 1.5 9.2 4.0 2.4 1 1 1 2 2 2 0 MbeB-like, N-term conserved region TMPIT PF07851.13 CDJ87008.1 - 0.51 9.5 5.4 0.6 9.3 5.4 1.0 1 0 0 1 1 1 0 TMPIT-like protein Spc24 PF08286.11 CDJ87008.1 - 1.7 8.9 6.6 2.3 8.5 6.6 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 XhlA PF10779.9 CDJ87008.1 - 3 8.1 5.6 3.7 7.8 4.3 1.8 1 1 0 1 1 1 0 Haemolysin XhlA ARS2 PF04959.13 CDJ87009.1 - 3.2e-48 164.7 0.1 6.8e-48 163.6 0.1 1.5 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DUF3546 PF12066.8 CDJ87009.1 - 1.2e-35 122.0 3.8 3.9e-35 120.4 3.8 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) Peptidase_C48 PF02902.19 CDJ87010.1 - 1.2e-44 152.7 1.3 3.3e-44 151.3 1.3 1.8 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Prp19 PF08606.11 CDJ87010.1 - 2.5e-32 110.7 1.4 5.3e-32 109.6 1.4 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 CDJ87010.1 - 2.9e-23 81.7 12.3 2e-06 28.4 0.0 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ87010.1 - 1.4e-10 41.3 4.5 0.0049 17.1 0.0 5.3 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain U-box PF04564.15 CDJ87010.1 - 1.3e-06 28.4 0.0 3.5e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 U-box domain HPS3_N PF14761.6 CDJ87010.1 - 0.00028 20.5 0.1 0.35 10.4 0.0 2.7 3 0 0 3 3 3 2 Hermansky-Pudlak syndrome 3 zf-NOSIP PF15906.5 CDJ87010.1 - 0.0037 17.4 0.0 0.008 16.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Ge1_WD40 PF16529.5 CDJ87010.1 - 0.0057 15.7 0.1 0.54 9.2 0.0 2.9 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-Nse PF11789.8 CDJ87010.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DivIC PF04977.15 CDJ87010.1 - 0.59 9.9 2.1 2.1 8.2 2.1 1.9 1 0 0 1 1 1 0 Septum formation initiator Prefoldin_2 PF01920.20 CDJ87010.1 - 0.63 10.0 3.6 0.31 11.0 0.9 1.9 2 0 0 2 2 2 0 Prefoldin subunit Mito_carr PF00153.27 CDJ87011.1 - 6.1e-59 196.0 1.9 1.6e-19 69.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HGTP_anticodon PF03129.20 CDJ87012.1 - 1.1e-19 70.4 0.0 5e-19 68.3 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain WHEP-TRS PF00458.20 CDJ87012.1 - 1e-10 41.6 4.2 2.3e-10 40.5 4.2 1.7 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_2b PF00587.25 CDJ87012.1 - 4e-10 39.9 0.0 1.7e-09 37.9 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) AAA_32 PF13654.6 CDJ87012.1 - 0.71 8.6 5.3 1.1 7.9 0.2 2.3 2 0 0 2 2 2 0 AAA domain AMOP PF03782.17 CDJ87014.1 - 7.4e-45 152.6 9.6 1.6e-44 151.5 9.6 1.6 1 0 0 1 1 1 1 AMOP domain VWD PF00094.25 CDJ87014.1 - 7.1e-31 107.6 0.1 1.9e-30 106.2 0.1 1.8 1 0 0 1 1 1 1 von Willebrand factor type D domain NIDO PF06119.14 CDJ87014.1 - 2.2e-20 73.4 0.5 2.2e-20 73.4 0.5 2.8 3 0 0 3 3 3 1 Nidogen-like Sushi PF00084.20 CDJ87014.1 - 3.4e-08 34.0 1.2 2.5e-07 31.2 0.3 2.9 3 0 0 3 3 3 1 Sushi repeat (SCR repeat) FtsK_4TM PF13491.6 CDJ87014.1 - 1.6 8.4 3.6 19 4.9 0.4 2.3 2 0 0 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE 7tm_1 PF00001.21 CDJ87015.1 - 1.3e-64 218.1 0.7 2.4e-64 217.2 0.7 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ87015.1 - 1e-06 28.4 11.6 0.0098 15.3 0.1 3.2 3 0 0 3 3 3 3 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 CDJ87015.1 - 0.00022 21.0 6.9 0.00025 20.9 1.8 2.4 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srbc PF10316.9 CDJ87015.1 - 0.013 15.1 11.9 0.043 13.3 11.9 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srbc Acid_phosphat_B PF03767.14 CDJ87015.1 - 0.036 13.6 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF202 PF02656.15 CDJ87015.1 - 0.19 12.2 0.7 2 8.9 0.2 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF202) DUF4519 PF15012.6 CDJ87015.1 - 7.5 6.8 5.6 3.7 7.8 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) fn3 PF00041.21 CDJ87016.1 - 0.001 19.4 0.7 0.18 12.1 0.0 3.0 2 1 0 2 2 2 2 Fibronectin type III domain PLL PF18587.1 CDJ87016.1 - 0.071 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 PTX/LNS-Like (PLL) domain UPF0172 PF03665.13 CDJ87017.1 - 3.4e-38 131.6 0.0 3.8e-38 131.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) NDK PF00334.19 CDJ87018.1 - 4e-55 185.5 0.0 4.5e-55 185.4 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF273 PF03314.14 CDJ87019.1 - 7.3e-62 208.8 2.5 1.2e-61 208.1 2.5 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF273 START PF01852.19 CDJ87019.1 - 5.3e-48 163.2 0.9 1.2e-47 162.0 0.2 1.9 2 0 0 2 2 2 1 START domain Glyco_transf_34 PF05637.12 CDJ87019.1 - 0.00029 20.7 4.2 0.085 12.6 1.8 2.4 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF4159 PF13709.6 CDJ87019.1 - 0.022 14.2 0.3 0.053 12.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4159) PH_8 PF15409.6 CDJ87019.1 - 0.054 13.8 0.0 0.33 11.3 0.0 2.4 1 0 0 1 1 1 0 Pleckstrin homology domain LisH_2 PF16045.5 CDJ87019.1 - 0.25 10.4 2.4 5.3 6.2 0.0 2.7 2 0 0 2 2 2 0 LisH Prok-RING_1 PF14446.6 CDJ87020.1 - 4.3e-05 23.4 8.1 0.00012 21.9 8.1 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PHD_2 PF13831.6 CDJ87020.1 - 0.0012 18.4 1.9 0.0012 18.4 1.9 2.2 2 0 0 2 2 2 1 PHD-finger SMC_Nse1 PF07574.13 CDJ87020.1 - 0.0018 18.2 0.0 0.28 11.0 0.0 2.2 1 1 1 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 CDJ87020.1 - 0.0044 17.3 8.9 0.0047 17.2 6.2 2.3 2 0 0 2 2 2 1 RING-like domain zf-RING_2 PF13639.6 CDJ87020.1 - 0.019 15.3 4.8 0.06 13.7 4.8 1.9 1 0 0 1 1 1 0 Ring finger domain C1_2 PF03107.16 CDJ87020.1 - 0.07 13.5 3.3 0.19 12.0 3.3 1.8 1 0 0 1 1 1 0 C1 domain PHD PF00628.29 CDJ87020.1 - 1.5 8.8 13.5 0.074 13.0 6.1 2.6 3 0 0 3 3 3 0 PHD-finger C1_1 PF00130.22 CDJ87020.1 - 3.3 7.7 10.3 0.16 11.9 4.6 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MoaE PF02391.17 CDJ87022.1 - 2.1e-14 53.8 0.0 4.2e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 MoaE protein AAA_18 PF13238.6 CDJ87022.1 - 1.2e-06 29.1 0.0 3.6e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CDJ87022.1 - 0.0014 18.7 0.0 0.0045 17.1 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.14 CDJ87022.1 - 0.0054 16.6 0.3 0.011 15.6 0.3 1.6 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B dNK PF01712.19 CDJ87022.1 - 0.0084 16.0 0.1 0.31 10.8 0.0 2.4 2 0 0 2 2 2 1 Deoxynucleoside kinase PRK PF00485.18 CDJ87022.1 - 0.0087 15.8 0.3 0.038 13.7 0.1 2.0 1 1 1 2 2 2 1 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.10 CDJ87022.1 - 0.023 14.2 0.0 0.057 12.8 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.27 CDJ87022.1 - 0.034 14.7 0.0 0.085 13.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 CDJ87022.1 - 0.058 12.7 0.0 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.6 CDJ87022.1 - 0.059 13.6 0.0 0.25 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 CDJ87022.1 - 0.061 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_14 PF13173.6 CDJ87022.1 - 0.072 13.1 0.1 0.3 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CDJ87022.1 - 0.13 12.6 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase MIEAP PF16026.5 CDJ87022.1 - 0.14 12.3 0.2 15 5.7 0.0 2.3 1 1 1 2 2 2 0 Mitochondria-eating protein Torsin PF06309.11 CDJ87022.1 - 0.17 12.0 0.1 0.56 10.3 0.0 1.9 2 0 0 2 2 2 0 Torsin T2SSE PF00437.20 CDJ87022.1 - 0.19 10.8 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Sema PF01403.19 CDJ87023.1 - 8.5e-52 176.4 0.1 1.4e-51 175.7 0.1 1.3 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 CDJ87023.1 - 0.00017 22.0 5.7 0.00037 21.0 5.4 1.8 1 1 0 1 1 1 1 Plexin repeat PSI_integrin PF17205.3 CDJ87023.1 - 0.051 13.3 2.5 0.17 11.7 2.5 1.9 1 0 0 1 1 1 0 Integrin plexin domain MutL_C PF08676.11 CDJ87024.1 - 1.4e-16 60.6 0.0 8.2e-08 32.1 0.0 2.9 2 1 1 3 3 3 2 MutL C terminal dimerisation domain bZIP_1 PF00170.21 CDJ87025.1 - 5.2e-05 23.3 5.8 8.8e-05 22.5 5.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor NRBF2 PF08961.10 CDJ87025.1 - 0.00021 20.9 1.7 0.00032 20.4 1.7 1.2 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator DivIC PF04977.15 CDJ87025.1 - 0.00094 18.9 4.6 0.0017 18.1 4.6 1.3 1 0 0 1 1 1 1 Septum formation initiator JIP_LZII PF16471.5 CDJ87025.1 - 0.0025 18.0 1.6 0.0044 17.2 1.1 1.6 2 0 0 2 2 2 1 JNK-interacting protein leucine zipper II bZIP_2 PF07716.15 CDJ87025.1 - 0.012 15.6 6.7 0.012 15.6 6.7 2.0 1 1 1 2 2 2 0 Basic region leucine zipper Uso1_p115_C PF04871.13 CDJ87025.1 - 0.015 15.7 1.5 0.022 15.1 1.5 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region YabA PF06156.13 CDJ87025.1 - 0.019 15.6 1.4 0.031 14.9 1.4 1.3 1 0 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 CDJ87025.1 - 0.025 15.0 3.1 0.046 14.2 3.1 1.5 1 0 0 1 1 1 0 Cell division protein ZapB LCD1 PF09798.9 CDJ87025.1 - 0.028 13.0 1.4 0.036 12.6 1.4 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Csm1_N PF18504.1 CDJ87025.1 - 0.029 14.7 2.3 0.047 14.0 2.3 1.3 1 0 0 1 1 1 0 Csm1 N-terminal domain DUF5017 PF16409.5 CDJ87025.1 - 0.031 13.8 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5017) HAUS-augmin3 PF14932.6 CDJ87025.1 - 0.036 13.6 1.2 0.047 13.3 1.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 GAS PF13851.6 CDJ87025.1 - 0.046 13.1 4.0 0.064 12.6 4.0 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ADIP PF11559.8 CDJ87025.1 - 0.12 12.5 5.3 0.16 12.0 5.3 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding bZIP_Maf PF03131.17 CDJ87025.1 - 0.47 11.0 6.2 0.78 10.3 6.2 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor APC_u14 PF16635.5 CDJ87025.1 - 1.8 9.1 7.6 1.1 9.9 4.6 2.0 1 1 1 2 2 2 0 Unstructured region on APC between SAMP and APC_crr FYVE_2 PF02318.16 CDJ87026.1 - 3.9e-14 52.9 11.2 3.6e-09 36.9 7.2 2.3 2 0 0 2 2 2 2 FYVE-type zinc finger NICE-1 PF15845.5 CDJ87026.1 - 4.2 8.2 13.3 8 7.3 13.3 1.5 1 0 0 1 1 1 0 Cysteine-rich C-terminal 1 family DZR PF12773.7 CDJ87026.1 - 4.2 7.5 12.7 56 3.9 2.0 2.3 1 1 1 2 2 2 0 Double zinc ribbon zf-piccolo PF05715.13 CDJ87026.1 - 7.6 6.8 16.8 61 3.9 16.6 2.3 1 1 1 2 2 2 0 Piccolo Zn-finger CNDH2_N PF06278.11 CDJ87027.1 - 3.3e-24 85.2 0.3 9.5e-24 83.8 0.1 1.8 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal CNDH2_M PF16869.5 CDJ87027.1 - 4.5e-05 24.2 0.0 0.00016 22.4 0.0 2.0 1 0 0 1 1 1 1 PF16858 Cnd2 PF05786.14 CDJ87027.1 - 0.0015 17.3 0.3 0.0015 17.3 0.3 1.8 2 0 0 2 2 2 1 Condensin complex subunit 2 PRP1_N PF06424.12 CDJ87027.1 - 2 8.8 11.7 0.13 12.7 3.4 2.6 2 1 0 2 2 2 0 PRP1 splicing factor, N-terminal Sec20 PF03908.13 CDJ87028.1 - 0.0043 16.9 0.5 0.66 9.9 0.0 2.2 1 1 1 2 2 2 2 Sec20 ApoL PF05461.11 CDJ87028.1 - 0.022 14.1 0.2 0.027 13.8 0.2 1.1 1 0 0 1 1 1 0 Apolipoprotein L Complex1_LYR_2 PF13233.6 CDJ87028.1 - 0.029 15.1 2.7 0.051 14.3 2.7 1.4 1 1 0 1 1 1 0 Complex1_LYR-like Fib_alpha PF08702.10 CDJ87028.1 - 0.21 11.8 1.0 0.25 11.5 1.0 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Cu-oxidase_3 PF07732.15 CDJ87029.1 - 5.1e-33 113.6 5.0 3.1e-30 104.6 0.2 3.9 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 CDJ87029.1 - 1.5e-27 96.0 10.7 4.2e-23 81.6 3.6 4.7 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 CDJ87029.1 - 1.2e-18 67.7 0.0 2.8e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 Multicopper oxidase AAA_12 PF13087.6 CDJ87031.1 - 4.4e-38 130.9 0.0 1e-37 129.7 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CDJ87031.1 - 2.6e-10 40.3 0.1 4.6e-06 26.5 0.3 2.3 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 CDJ87031.1 - 9.3e-09 35.5 0.0 1.7e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ87031.1 - 2e-07 31.4 0.2 4.1e-05 23.9 0.1 3.0 2 1 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 CDJ87031.1 - 7.7e-05 22.6 0.1 0.0027 17.6 0.0 2.5 2 0 0 2 2 2 1 Helicase DEAD PF00270.29 CDJ87031.1 - 0.0001 22.1 0.1 0.0074 16.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Viral_helicase1 PF01443.18 CDJ87031.1 - 0.00069 19.4 0.1 0.0065 16.2 0.1 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 CDJ87031.1 - 0.00081 19.0 4.0 0.095 12.2 1.3 2.5 2 1 0 2 2 2 2 UvrD/REP helicase N-terminal domain ResIII PF04851.15 CDJ87031.1 - 0.0043 17.1 0.0 0.013 15.5 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit P22_AR_C PF10548.9 CDJ87031.1 - 0.09 13.0 0.0 0.32 11.2 0.0 1.9 2 0 0 2 2 2 0 P22AR C-terminal domain UvrD_C_2 PF13538.6 CDJ87031.1 - 0.12 12.2 0.1 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Ribosomal_L7Ae PF01248.26 CDJ87032.1 - 5.1e-23 80.6 0.0 9.6e-23 79.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SRP40_C PF05022.12 CDJ87032.1 - 3e-20 72.9 3.4 7.7e-20 71.5 3.4 1.7 1 0 0 1 1 1 1 SRP40, C-terminal domain DTHCT PF08070.11 CDJ87032.1 - 3.2e-05 24.6 318.1 1.8 9.3 16.9 12.9 1 1 11 12 12 12 11 DTHCT (NUC029) region Putative_PNPOx PF01243.20 CDJ87033.1 - 4.5e-23 81.2 0.0 7.8e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 CDJ87033.1 - 6.2e-18 64.6 2.0 3.3e-17 62.3 1.6 2.2 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 CDJ87033.1 - 5.7e-08 33.3 0.0 1.2e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase TH1 PF04858.13 CDJ87033.1 - 0.024 13.3 0.0 0.032 12.9 0.0 1.1 1 0 0 1 1 1 0 TH1 protein TMEM144 PF07857.12 CDJ87034.1 - 2e-128 428.1 14.7 2.3e-128 427.9 14.7 1.0 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 CDJ87034.1 - 5.4e-10 39.1 20.1 2.1e-09 37.1 3.1 3.0 2 2 1 3 3 3 2 Sugar transport protein NDUF_C2 PF06374.11 CDJ87034.1 - 0.1 12.8 0.0 0.35 11.0 0.0 1.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) TssO PF17561.2 CDJ87034.1 - 0.18 11.9 0.1 0.47 10.6 0.1 1.6 1 0 0 1 1 1 0 Type VI secretion system, TssO DUF846 PF05832.12 CDJ87034.1 - 2.5 8.1 9.0 0.11 12.5 2.9 1.9 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF846) TssN PF17555.2 CDJ87034.1 - 3.6 6.9 8.0 0.22 10.9 1.2 2.3 2 1 1 3 3 3 0 Type VI secretion system, TssN L6_membrane PF05805.12 CDJ87036.1 - 0.022 14.4 0.2 0.034 13.7 0.2 1.2 1 0 0 1 1 1 0 L6 membrane protein SPP PF06550.11 CDJ87036.1 - 0.041 13.4 1.2 0.057 12.9 1.2 1.1 1 0 0 1 1 1 0 Signal-peptide peptidase, presenilin aspartyl protease Mito_carr PF00153.27 CDJ87037.1 - 2.6e-46 155.5 5.9 2.2e-19 69.1 0.3 4.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CDJ87037.1 - 0.0032 16.7 0.5 0.039 13.1 0.5 2.1 1 1 0 1 1 1 1 Gammaproteobacterial serine protease Sds3 PF08598.11 CDJ87038.1 - 3e-14 53.5 2.9 3.4e-14 53.4 2.9 1.1 1 0 0 1 1 1 1 Sds3-like DUF1344 PF07076.11 CDJ87038.1 - 0.17 11.8 0.9 0.98 9.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) CENP-O PF09496.10 CDJ87038.1 - 0.24 11.3 4.5 0.37 10.7 2.5 1.9 2 0 0 2 2 2 0 Cenp-O kinetochore centromere component PspB PF06667.12 CDJ87038.1 - 0.63 10.1 5.4 0.38 10.8 2.0 2.0 2 0 0 2 2 2 0 Phage shock protein B Mitofilin PF09731.9 CDJ87038.1 - 2.6 6.8 12.1 3.5 6.3 12.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein AAA_33 PF13671.6 CDJ87039.1 - 7.4e-10 39.2 0.0 2.3e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain Smr PF01713.21 CDJ87039.1 - 8.6e-07 29.2 0.1 2.6e-06 27.7 0.1 1.9 1 0 0 1 1 1 1 Smr domain Zeta_toxin PF06414.12 CDJ87039.1 - 0.00042 19.7 0.0 0.0071 15.6 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin KTI12 PF08433.10 CDJ87039.1 - 0.0014 18.1 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 DUF1771 PF08590.10 CDJ87039.1 - 0.0018 18.6 6.8 0.0018 18.6 6.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) AAA_18 PF13238.6 CDJ87039.1 - 0.002 18.7 0.2 0.051 14.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.6 CDJ87039.1 - 0.005 17.3 0.0 0.019 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ87039.1 - 0.0066 16.8 0.3 0.14 12.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.9 CDJ87039.1 - 0.038 13.2 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 CDJ87039.1 - 0.044 13.1 0.0 0.096 12.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI HemY_N PF07219.13 CDJ87039.1 - 1.5 9.0 3.3 3.2 8.0 3.3 1.4 1 0 0 1 1 1 0 HemY protein N-terminus Voltage_CLC PF00654.20 CDJ87040.1 - 1.2e-83 281.3 25.2 1.7e-83 280.8 25.2 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 CDJ87040.1 - 2.2e-06 28.0 0.3 0.021 15.2 0.1 2.7 2 0 0 2 2 2 2 CBS domain T3SS_HrpK1 PF16937.5 CDJ87040.1 - 0.025 14.3 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Type III secretion system translocator protein, HrpF Ion_trans_2 PF07885.16 CDJ87042.1 - 2.7e-35 120.2 18.2 2e-18 66.1 2.4 3.1 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CDJ87042.1 - 8.5e-09 35.0 6.7 5.4e-05 22.5 0.4 2.1 2 0 0 2 2 2 2 Ion transport protein IRK PF01007.20 CDJ87042.1 - 6.1e-05 22.9 1.0 0.0017 18.1 0.2 2.8 2 0 0 2 2 2 1 Inward rectifier potassium channel transmembrane domain DUF2254 PF10011.9 CDJ87042.1 - 0.00047 19.1 3.6 0.00057 18.8 0.7 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2254) DUF5083 PF16890.5 CDJ87042.1 - 0.04 13.6 0.7 0.2 11.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5083) Pox_A9 PF04835.12 CDJ87042.1 - 6 7.1 9.2 15 5.8 0.3 3.8 3 0 0 3 3 3 0 A9 protein conserved region RVT_1 PF00078.27 CDJ87044.1 - 4e-09 36.3 0.0 6.1e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7TM_GPCR_Srd PF10317.9 CDJ87045.1 - 1.6e-36 126.0 9.4 1.9e-36 125.8 9.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Str PF10326.9 CDJ87045.1 - 1.2e-08 34.6 7.2 1.6e-08 34.3 7.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str Trp_dioxygenase PF03301.13 CDJ87046.1 - 1.8e-153 511.0 3.6 2.1e-153 510.8 3.6 1.0 1 0 0 1 1 1 1 Tryptophan 2,3-dioxygenase Forkhead PF00250.18 CDJ87047.1 - 5.5e-29 100.3 0.1 1.4e-28 98.9 0.1 1.7 1 0 0 1 1 1 1 Forkhead domain FOXP-CC PF16159.5 CDJ87047.1 - 1.5e-24 86.4 7.1 3.8e-24 85.1 7.1 1.7 1 0 0 1 1 1 1 FOXP coiled-coil domain zf-C2H2_2 PF12756.7 CDJ87047.1 - 0.37 11.1 2.5 0.36 11.2 0.6 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) SYF2 PF08231.12 CDJ87048.1 - 2.1e-44 151.8 2.2 2.1e-44 151.8 2.2 1.9 2 0 0 2 2 2 1 SYF2 splicing factor DHHC PF01529.20 CDJ87049.1 - 1.8e-34 118.7 3.7 1.8e-34 118.7 3.7 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase IBR PF01485.21 CDJ87050.1 - 4.4e-18 65.3 24.8 4.9e-13 49.1 3.0 4.2 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain Nop PF01798.18 CDJ87051.1 - 7.6e-67 225.1 0.0 1.5e-66 224.2 0.0 1.5 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 CDJ87051.1 - 4.3e-42 143.8 5.5 7e-42 143.2 5.5 1.4 1 0 0 1 1 1 1 Prp31 C terminal domain Beach PF02138.18 CDJ87052.1 - 7.7e-120 399.4 0.1 1.1e-119 399.0 0.1 1.2 1 0 0 1 1 1 1 Beige/BEACH domain FYVE PF01363.21 CDJ87052.1 - 9e-17 61.0 17.5 2.3e-16 59.7 17.5 1.7 1 0 0 1 1 1 1 FYVE zinc finger WD40 PF00400.32 CDJ87052.1 - 1.2e-06 29.1 19.6 0.001 19.8 0.6 5.8 4 1 0 4 4 4 3 WD domain, G-beta repeat zinc_ribbon_4 PF13717.6 CDJ87052.1 - 3.7 7.6 9.5 17 5.4 9.5 2.2 1 1 0 1 1 1 0 zinc-ribbon domain PknG_rubred PF16919.5 CDJ87052.1 - 6.2 7.0 7.1 0.56 10.4 1.0 2.1 1 1 1 2 2 2 0 Protein kinase G rubredoxin domain Collagen PF01391.18 CDJ87053.1 - 5e-26 90.2 105.0 3.5e-05 23.5 10.5 4.2 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) SAM_3 PF18016.1 CDJ87055.1 - 2.9e-23 81.4 0.9 7.5e-23 80.1 0.2 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PTB PF08416.13 CDJ87055.1 - 2.8e-18 66.3 0.0 5.6e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH3_2 PF07653.17 CDJ87055.1 - 2.7e-10 39.7 0.0 6.8e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDJ87055.1 - 4.1e-08 32.7 0.0 7.9e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CDJ87055.1 - 1.5e-06 28.0 0.0 3.3e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 CDJ87055.1 - 0.0042 17.5 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 Helically-extended SH3 domain SAM_PNT PF02198.16 CDJ87055.1 - 0.0043 17.0 0.1 0.0088 16.0 0.1 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SH3_3 PF08239.11 CDJ87055.1 - 0.096 13.0 0.2 0.19 12.0 0.2 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain ATG7_N PF16420.5 CDJ87056.1 - 2.8e-60 204.5 0.1 4.7e-60 203.8 0.1 1.3 1 1 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 CDJ87057.1 - 8.5e-13 48.2 0.0 8.7e-13 48.2 0.0 1.0 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 CDJ87057.1 - 0.0005 20.1 0.0 0.0006 19.9 0.0 1.1 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 CDJ87057.1 - 0.0029 17.0 0.0 0.0031 16.9 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 CDJ87057.1 - 0.02 14.6 0.0 0.02 14.6 0.0 1.0 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase PglD_N PF17836.1 CDJ87057.1 - 0.029 15.0 0.0 0.036 14.7 0.0 1.1 1 0 0 1 1 1 0 PglD N-terminal domain EamA PF00892.20 CDJ87057.1 - 0.042 14.0 0.0 0.045 13.9 0.0 1.1 1 0 0 1 1 1 0 EamA-like transporter family TrkA_N PF02254.18 CDJ87057.1 - 0.087 13.1 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 CDJ87057.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 CDJ87057.1 - 0.22 10.7 0.0 0.35 10.1 0.0 1.3 1 1 0 1 1 1 0 FAD binding domain ThiF PF00899.21 CDJ87058.1 - 5.1e-15 55.5 0.0 7.9e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 ThiF family zf-C2H2 PF00096.26 CDJ87059.1 - 1.6e-12 47.1 16.5 3.6e-06 27.1 1.4 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ87059.1 - 1.9e-12 46.9 15.9 0.00074 20.1 1.0 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDJ87059.1 - 5.3e-10 39.3 16.9 0.00031 21.0 0.8 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-Di19 PF05605.12 CDJ87059.1 - 3.5e-05 24.0 10.2 0.0066 16.7 0.0 3.1 2 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CDJ87059.1 - 0.0027 18.0 8.2 0.12 12.8 0.2 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type BolA PF01722.18 CDJ87059.1 - 0.004 17.4 1.0 0.0054 17.0 0.1 1.7 2 0 0 2 2 1 1 BolA-like protein zf-C2HC_2 PF13913.6 CDJ87059.1 - 0.0096 15.8 9.5 1.8 8.5 0.3 3.5 3 0 0 3 3 3 2 zinc-finger of a C2HC-type DUF629 PF04780.12 CDJ87059.1 - 0.013 14.0 10.5 0.032 12.8 0.7 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_8 PF15909.5 CDJ87059.1 - 0.02 15.2 6.0 0.031 14.6 5.2 1.7 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 CDJ87059.1 - 0.021 14.8 0.4 0.021 14.8 0.4 3.7 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CDJ87059.1 - 0.038 14.7 7.2 3.5 8.3 1.7 2.5 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 CDJ87059.1 - 0.046 14.1 11.1 1.4 9.2 1.2 3.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-RING_11 PF17123.5 CDJ87059.1 - 0.098 12.4 2.2 5.1 6.9 0.1 2.6 2 0 0 2 2 2 0 RING-like zinc finger C1_4 PF07975.12 CDJ87059.1 - 0.12 12.6 6.9 2.1 8.7 0.7 2.4 2 0 0 2 2 2 0 TFIIH C1-like domain zf-C2H2_jaz PF12171.8 CDJ87059.1 - 0.16 12.3 5.6 1.3 9.4 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FYVE PF01363.21 CDJ87059.1 - 0.21 11.8 10.8 5.7 7.2 2.8 3.2 1 1 1 2 2 2 0 FYVE zinc finger Elf1 PF05129.13 CDJ87059.1 - 0.24 11.5 10.7 0.36 10.9 5.0 2.8 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like zf-C2H2_9 PF16293.5 CDJ87059.1 - 0.26 11.1 5.9 8.1 6.4 0.2 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) VATC PF18716.1 CDJ87059.1 - 0.26 11.1 5.8 20 5.1 0.1 3.4 3 0 0 3 3 3 0 Vms1-associating treble clef domain zf-Sec23_Sec24 PF04810.15 CDJ87059.1 - 0.4 10.8 6.5 1.2 9.3 0.2 3.2 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger PHD_4 PF16866.5 CDJ87059.1 - 0.48 10.6 11.3 3.2 7.9 4.7 2.8 1 1 1 2 2 2 0 PHD-finger DUF1178 PF06676.11 CDJ87059.1 - 0.58 10.5 6.1 1.1 9.7 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1178) zf-BED PF02892.15 CDJ87059.1 - 0.74 9.9 13.9 10 6.3 1.0 3.5 1 1 2 3 3 3 0 BED zinc finger NADH-G_4Fe-4S_3 PF10588.9 CDJ87059.1 - 0.79 9.3 6.0 18 4.9 0.1 3.3 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Zn-C2H2_12 PF18112.1 CDJ87059.1 - 1.9 9.0 8.2 10 6.7 0.4 3.7 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain UBZ_FAAP20 PF15750.5 CDJ87059.1 - 2 8.4 9.4 3.4 7.7 0.2 3.3 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger TRAF6_Z2 PF18048.1 CDJ87059.1 - 2.8 8.1 7.9 0.4 10.8 0.5 2.8 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 PHD PF00628.29 CDJ87059.1 - 3 7.8 10.7 2.6e+02 1.6 10.7 2.6 1 1 0 1 1 1 0 PHD-finger zf-C2HE PF16278.5 CDJ87059.1 - 9.1 6.8 11.9 9.5 6.8 7.8 2.8 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger SNF PF00209.18 CDJ87061.1 - 1.7e-12 46.8 1.8 2.2e-12 46.5 1.8 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family GEMIN8 PF15348.6 CDJ87061.1 - 0.0056 17.0 1.6 0.0074 16.6 1.6 1.2 1 0 0 1 1 1 1 Gemini of Cajal bodies-associated protein 8 Myc_N PF01056.18 CDJ87061.1 - 0.1 12.5 0.3 0.13 12.2 0.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region RecO_C PF02565.15 CDJ87061.1 - 0.21 11.4 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Recombination protein O C terminal Interfer-bind PF09294.10 CDJ87061.1 - 0.56 10.6 2.1 0.67 10.3 0.1 2.1 1 1 1 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III VWA PF00092.28 CDJ87062.1 - 3.3e-11 43.7 0.0 1e-10 42.2 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CDJ87062.1 - 1.4e-07 32.1 1.1 2.6e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain SPX PF03105.19 CDJ87062.1 - 4.2 7.2 10.0 6.7 6.5 10.0 1.2 1 0 0 1 1 1 0 SPX domain RVT_1 PF00078.27 CDJ87063.1 - 1.8e-22 79.9 0.0 2.5e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NBP1 PF08537.10 CDJ87064.1 - 0.0053 16.2 0.3 0.0068 15.9 0.3 1.1 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 Beta_propel PF09826.9 CDJ87064.1 - 0.025 13.4 0.3 0.031 13.1 0.3 1.0 1 0 0 1 1 1 0 Beta propeller domain DUF4570 PF15134.6 CDJ87064.1 - 0.039 14.0 2.1 0.06 13.4 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) DUF2760 PF10816.8 CDJ87066.1 - 0.06 13.2 0.1 0.097 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2760) MCU PF04678.13 CDJ87066.1 - 0.062 13.4 0.9 0.081 13.0 0.9 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter NUDIX PF00293.28 CDJ87067.1 - 7e-17 61.7 0.4 1.2e-16 61.0 0.1 1.5 2 0 0 2 2 2 1 NUDIX domain Nudix_hydro PF18290.1 CDJ87067.1 - 5.9e-16 58.2 0.1 1.1e-15 57.4 0.1 1.4 1 0 0 1 1 1 1 Nudix hydrolase domain TraB PF01963.17 CDJ87068.1 - 7.7e-52 176.8 0.0 9.7e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 TraB family SCIMP PF15050.6 CDJ87070.1 - 0.023 15.1 2.8 0.14 12.6 2.3 2.3 1 1 1 2 2 2 0 SCIMP protein COX14 PF14880.6 CDJ87070.1 - 0.061 13.2 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Cytochrome oxidase c assembly MarC PF01914.17 CDJ87070.1 - 0.085 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 MarC family integral membrane protein LapA_dom PF06305.11 CDJ87070.1 - 0.11 12.4 1.0 0.35 10.7 0.0 2.3 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Connexin PF00029.19 CDJ87070.1 - 0.96 9.2 4.2 0.59 9.9 0.1 2.1 2 0 0 2 2 2 0 Connexin AAA_23 PF13476.6 CDJ87070.1 - 1.7 9.1 10.7 1.9 8.9 1.4 2.2 2 0 0 2 2 2 0 AAA domain MSP1a PF11670.8 CDJ87070.1 - 2.4 7.4 3.6 1.9 7.7 0.9 2.1 2 1 1 3 3 3 0 Major surface protein 1a (MSP1a) DivIC PF04977.15 CDJ87070.1 - 2.5 8.0 8.2 9.5 6.1 0.2 3.2 3 0 0 3 3 3 0 Septum formation initiator Ribosomal_60s PF00428.19 CDJ87070.1 - 3.9 8.1 10.3 6.4 7.4 0.3 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4199 PF13858.6 CDJ87070.1 - 7.3 7.0 6.6 1.7 9.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF4337 PF14235.6 CDJ87070.1 - 8.2 6.5 7.9 1.3 9.1 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) MFS_1 PF07690.16 CDJ87073.1 - 3.3e-09 36.1 7.4 3.7e-09 36.0 7.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ87073.1 - 0.019 13.9 2.1 0.036 12.9 2.1 1.5 1 1 0 1 1 1 0 Sugar (and other) transporter Tetraspanin PF00335.20 CDJ87074.1 - 2.6e-55 187.6 10.1 3.1e-55 187.4 10.1 1.1 1 0 0 1 1 1 1 Tetraspanin family Kelch_1 PF01344.25 CDJ87075.1 - 4.5e-27 93.4 9.6 7e-07 28.7 0.1 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 CDJ87075.1 - 2.6e-23 81.8 7.2 1.5e-06 28.1 0.0 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ87075.1 - 4.7e-19 67.9 9.7 1.2e-06 28.3 0.1 6.5 6 0 0 6 6 6 4 Kelch motif CUB PF00431.20 CDJ87075.1 - 7.5e-15 55.2 0.0 2.2e-14 53.7 0.0 1.8 1 0 0 1 1 1 1 CUB domain Kelch_6 PF13964.6 CDJ87075.1 - 9.3e-14 51.1 9.6 0.01 16.1 0.0 6.5 6 0 0 6 6 6 3 Kelch motif PSI PF01437.25 CDJ87075.1 - 6.4e-13 49.0 47.3 1.1e-07 32.2 6.5 8.7 9 2 0 9 9 6 3 Plexin repeat Kelch_2 PF07646.15 CDJ87075.1 - 9.2e-13 47.6 10.4 0.15 12.1 0.0 7.1 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 CDJ87075.1 - 1.3e-11 44.4 7.4 0.13 12.6 0.0 6.8 6 0 0 6 6 6 4 Galactose oxidase, central domain Laminin_EGF PF00053.24 CDJ87075.1 - 5e-08 32.9 43.7 2.3e-06 27.6 18.3 8.2 8 2 1 9 9 6 3 Laminin EGF domain EGF_Tenascin PF18720.1 CDJ87075.1 - 0.0018 18.3 9.3 0.0018 18.3 9.3 6.7 6 0 0 6 6 5 2 Tenascin EGF domain EGF_2 PF07974.13 CDJ87075.1 - 0.0043 17.4 15.9 0.0043 17.4 15.9 8.6 8 1 0 8 8 6 3 EGF-like domain Saf_2TM PF18303.1 CDJ87075.1 - 0.0079 15.8 0.1 0.014 15.0 0.1 1.3 1 0 0 1 1 1 1 SAVED-fused 2TM effector domain POB3_N PF17292.2 CDJ87075.1 - 0.069 13.6 0.0 1.2 9.6 0.0 2.4 1 1 1 2 2 2 0 POB3-like N-terminal PH domain Aha1_N PF09229.11 CDJ87075.1 - 0.14 12.3 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Activator of Hsp90 ATPase, N-terminal SieB PF14163.6 CDJ87075.1 - 0.17 11.4 0.1 0.3 10.6 0.1 1.3 1 0 0 1 1 1 0 Super-infection exclusion protein B LLGL PF08366.13 CDJ87076.1 - 1.9e-21 76.4 0.0 6.2e-21 74.7 0.0 1.9 1 0 0 1 1 1 1 LLGL2 ANAPC4_WD40 PF12894.7 CDJ87076.1 - 0.006 16.8 0.0 7.8 6.9 0.0 4.3 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ87076.1 - 0.01 16.6 0.2 6.9 7.7 0.0 4.4 3 0 0 3 3 3 0 WD domain, G-beta repeat SNF PF00209.18 CDJ87077.1 - 9.7e-171 569.0 33.2 1.3e-170 568.6 33.2 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF4094 PF13334.6 CDJ87077.1 - 0.75 10.3 2.5 1.3 9.5 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) PGAP1 PF07819.13 CDJ87079.1 - 3.7e-05 23.6 0.0 7.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 CDJ87079.1 - 0.00021 22.0 0.0 0.0005 20.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDJ87079.1 - 0.029 13.6 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 CDJ87079.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase RepA_N PF06970.11 CDJ87080.1 - 0.17 11.8 0.0 95 3.0 0.0 3.8 4 0 0 4 4 4 0 Replication initiator protein A (RepA) N-terminus HTH_48 PF17906.1 CDJ87081.1 - 3e-19 68.9 0.8 6.1e-19 67.9 0.8 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_23 PF13384.6 CDJ87081.1 - 1.9e-06 27.5 0.1 0.011 15.5 0.0 2.4 2 0 0 2 2 2 2 Homeodomain-like domain HTH_38 PF13936.6 CDJ87081.1 - 2.5e-06 27.2 0.2 5.6e-06 26.0 0.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_IS630 PF01710.16 CDJ87081.1 - 3.4e-06 27.1 0.0 4.1e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 CDJ87081.1 - 6e-06 26.8 0.0 8.4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 CDJ87081.1 - 2e-05 24.7 0.5 8.9e-05 22.7 0.2 1.9 2 0 0 2 2 2 1 Transposase HTH_28 PF13518.6 CDJ87081.1 - 3.3e-05 23.9 0.1 0.46 10.7 0.0 2.6 3 0 0 3 3 2 2 Helix-turn-helix domain HTH_50 PF18024.1 CDJ87081.1 - 0.00022 20.8 0.5 0.00046 19.7 0.0 1.8 2 0 0 2 2 1 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 CDJ87081.1 - 0.0056 17.0 0.1 3.4 8.0 0.1 2.2 1 1 1 2 2 2 2 Transposase HTH_11 PF08279.12 CDJ87081.1 - 0.0065 16.4 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 HTH domain HTH_29 PF13551.6 CDJ87081.1 - 0.0067 16.4 0.1 0.28 11.2 0.0 2.2 1 1 1 2 2 2 1 Winged helix-turn helix Terminase_5 PF06056.12 CDJ87081.1 - 0.013 15.4 0.0 2.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) TnsD PF15978.5 CDJ87081.1 - 0.015 14.3 0.3 0.015 14.3 0.3 1.2 1 1 0 1 1 1 0 Tn7-like transposition protein D IF2_N PF04760.15 CDJ87081.1 - 0.027 14.3 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region HTH_36 PF13730.6 CDJ87081.1 - 0.037 14.0 0.0 0.26 11.3 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 CDJ87081.1 - 0.045 13.2 0.1 0.38 10.2 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_6 PF01418.17 CDJ87081.1 - 0.053 13.5 0.0 0.18 11.8 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family HTH_10 PF04967.12 CDJ87081.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain HTH_40 PF14493.6 CDJ87081.1 - 0.11 12.9 0.2 0.25 11.8 0.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_terminase PF10668.9 CDJ87081.1 - 0.13 12.3 0.2 0.68 10.0 0.0 2.2 2 1 1 3 3 3 0 Phage terminase small subunit HTH_5 PF01022.20 CDJ87081.1 - 0.13 12.1 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family DUF4817 PF16087.5 CDJ87081.1 - 0.3 10.9 2.4 0.25 11.2 0.4 1.9 2 1 0 2 2 2 0 Helix-turn-helix domain (DUF4817) rve PF00665.26 CDJ87082.1 - 1e-05 25.7 0.1 4.2e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 CDJ87082.1 - 0.00014 21.6 0.0 0.00036 20.2 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 CDJ87083.1 - 1.3e-32 111.8 0.0 7.1e-32 109.4 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ87083.1 - 2.5e-31 108.1 0.0 1.8e-30 105.3 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ87083.1 - 2e-21 76.6 0.0 3.8e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ87083.1 - 4.4e-14 52.3 0.8 1.1e-13 51.0 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain DUF5314 PF17241.2 CDJ87083.1 - 0.05 13.3 0.2 0.13 11.9 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5314) DUF5641 PF18701.1 CDJ87084.1 - 6.3e-17 61.5 0.0 1.2e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5641) rve PF00665.26 CDJ87084.1 - 1.3e-10 41.5 0.0 1.9e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDJ87084.1 - 0.0012 18.6 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain 7tm_1 PF00001.21 CDJ87085.1 - 6.7e-27 94.5 20.2 9.5e-27 94.0 20.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SARAF PF06682.12 CDJ87088.1 - 0.074 12.7 0.0 0.081 12.6 0.0 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF1515 PF07439.11 CDJ87089.1 - 0.098 12.7 0.8 0.2 11.7 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) HemY_N PF07219.13 CDJ87089.1 - 0.32 11.2 0.1 0.32 11.2 0.1 2.3 2 1 1 3 3 3 0 HemY protein N-terminus Myc_target_1 PF15179.6 CDJ87089.1 - 3.8 7.4 6.3 0.24 11.3 1.2 1.6 2 0 0 2 2 2 0 Myc target protein 1 Neur_chan_memb PF02932.16 CDJ87089.1 - 9.4 6.2 16.0 25 4.8 0.1 2.2 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region 7TM_GPCR_Srx PF10328.9 CDJ87092.1 - 2.4e-32 112.6 9.7 2.9e-32 112.4 9.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Phage_holin_3_6 PF07332.11 CDJ87092.1 - 0.00062 19.8 0.1 0.074 13.1 0.0 2.2 1 1 1 2 2 2 2 Putative Actinobacterial Holin-X, holin superfamily III Exo_endo_phos PF03372.23 CDJ87093.1 - 3.1e-09 36.7 0.0 1.8e-08 34.2 0.0 2.2 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF410 PF04190.13 CDJ87094.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF410) DUF148 PF02520.17 CDJ87095.1 - 9.4e-26 90.1 2.2 1.1e-25 89.8 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 Spy1 PF11357.8 CDJ87095.1 - 0.15 12.3 0.4 0.22 11.8 0.4 1.3 1 0 0 1 1 1 0 Cell cycle regulatory protein BRE1 PF08647.11 CDJ87095.1 - 5.1 7.2 6.4 5.1 7.2 0.7 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF148 PF02520.17 CDJ87096.1 - 8.1e-18 64.5 0.6 9.8e-18 64.3 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 Pre-PUA PF17832.1 CDJ87097.1 - 1.4e-23 83.4 0.1 2.1e-23 82.8 0.1 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 CDJ87097.1 - 2e-20 72.5 0.0 3.2e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 PUA domain RAP80_UIM PF18282.1 CDJ87097.1 - 0.018 14.8 0.2 0.031 14.0 0.2 1.3 1 0 0 1 1 1 0 RAP80 N-terminal ubiquitin interaction motif Q_salvage PF10343.9 CDJ87098.1 - 1.5e-99 333.2 0.0 1.8e-99 332.9 0.0 1.0 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family adh_short PF00106.25 CDJ87099.1 - 1.8e-14 53.7 0.0 4.9e-14 52.3 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.21 CDJ87099.1 - 4.7e-09 36.1 0.0 6.8e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 CDJ87099.1 - 2e-07 30.8 0.0 4.6e-07 29.6 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 CDJ87099.1 - 0.00016 21.6 0.0 0.00028 20.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 CDJ87099.1 - 0.0019 18.1 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 CDJ87099.1 - 0.004 16.6 0.0 0.0057 16.1 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 CDJ87099.1 - 0.013 14.7 0.0 0.28 10.3 0.0 2.3 1 1 0 1 1 1 0 Male sterility protein RmlD_sub_bind PF04321.17 CDJ87099.1 - 0.013 14.6 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 CDJ87099.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.19 CDJ87099.1 - 0.041 12.9 0.0 0.061 12.3 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 CDJ87099.1 - 0.097 12.8 0.0 0.19 11.9 0.0 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 CDJ87099.1 - 0.16 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CDC45 PF02724.14 CDJ87101.1 - 0.61 8.3 4.8 0.69 8.1 4.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 CDJ87101.1 - 1.9 8.3 13.4 2.4 7.9 13.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4551 PF15087.6 CDJ87101.1 - 2 7.1 8.1 2.1 7.0 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RAP1 PF07218.11 CDJ87101.1 - 6.9 4.8 11.6 9 4.4 11.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Hid1 PF12722.7 CDJ87101.1 - 7.2 4.6 7.8 8.2 4.4 7.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein An_peroxidase PF03098.15 CDJ87103.1 - 1.1e-153 512.6 0.0 1.3e-153 512.3 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Collagen PF01391.18 CDJ87104.1 - 2.2e-27 94.6 95.2 1.3e-10 40.8 31.9 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ87104.1 - 0.007 16.4 0.2 0.012 15.7 0.2 1.4 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Oxysterol_BP PF01237.18 CDJ87105.1 - 7.5e-70 235.6 2.8 4.7e-61 206.7 1.1 2.8 2 1 0 2 2 2 2 Oxysterol-binding protein SCVP PF17619.2 CDJ87106.1 - 0.00042 21.1 0.0 0.00058 20.7 0.0 1.2 1 0 0 1 1 1 1 Secreted clade V proteins Nanovirus_C8 PF05629.11 CDJ87106.1 - 0.059 13.5 0.2 0.079 13.1 0.2 1.2 1 0 0 1 1 1 0 Nanovirus component 8 (C8) protein Cnd1 PF12717.7 CDJ87108.1 - 1.7e-22 80.2 15.2 5e-19 68.9 1.8 4.5 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDJ87108.1 - 2.9e-07 30.8 0.7 0.0093 16.3 0.1 4.4 3 1 1 4 4 4 2 HEAT repeats Cnd3 PF12719.7 CDJ87108.1 - 7.2e-07 28.7 1.9 1.4e-06 27.8 0.2 2.4 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 CDJ87108.1 - 2.8e-06 27.1 10.3 1.6 9.2 0.0 6.5 6 0 0 6 6 6 3 HEAT repeat Adaptin_N PF01602.20 CDJ87108.1 - 0.00086 18.0 6.0 0.04 12.5 1.6 2.8 2 1 1 3 3 3 3 Adaptin N terminal region Cohesin_HEAT PF12765.7 CDJ87108.1 - 0.031 14.6 0.1 2.7 8.4 0.1 3.1 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 CDJ87108.1 - 0.38 11.3 5.0 1.5e+02 3.0 0.0 5.2 5 0 0 5 5 5 0 HEAT-like repeat RVT_1 PF00078.27 CDJ87109.1 - 0.017 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1758 PF05585.12 CDJ87109.1 - 0.025 14.4 0.0 0.067 13.0 0.0 1.7 2 0 0 2 2 2 0 Putative peptidase (DUF1758) Glyco_transf_24 PF18404.1 CDJ87110.1 - 7.9e-77 258.3 0.2 9.4e-77 258.0 0.2 1.0 1 0 0 1 1 1 1 Glucosyltransferase 24 Lectin_C PF00059.21 CDJ87111.1 - 6.5e-13 49.3 0.2 1.3e-12 48.4 0.2 1.5 1 0 0 1 1 1 1 Lectin C-type domain CUB PF00431.20 CDJ87111.1 - 1e-07 32.3 0.1 1.8e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 CUB domain UL45 PF05473.12 CDJ87111.1 - 0.00066 19.4 0.2 0.0022 17.7 0.2 1.8 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like TMIE PF16038.5 CDJ87111.1 - 0.071 13.0 3.0 0.18 11.6 3.0 1.6 1 0 0 1 1 1 0 TMIE protein Herpes_UL73 PF03554.13 CDJ87111.1 - 0.21 11.6 1.7 0.57 10.2 1.7 1.7 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein RVP PF00077.20 CDJ87112.1 - 0.00026 21.2 0.1 0.0013 19.0 0.1 2.0 1 1 1 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CDJ87112.1 - 0.028 15.0 0.1 0.068 13.7 0.1 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease COOH-NH2_lig PF14395.6 CDJ87112.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Phage phiEco32-like COOH.NH2 ligase-type 2 AAA_30 PF13604.6 CDJ87113.1 - 8.2e-06 25.7 0.3 4.6e-05 23.2 0.4 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CDJ87113.1 - 1.3e-05 25.1 0.0 5.9e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 CDJ87113.1 - 0.0019 18.1 0.2 0.0047 16.8 0.1 1.7 2 0 0 2 2 2 1 Helicase DEAD PF00270.29 CDJ87113.1 - 0.002 17.9 0.2 0.0042 16.9 0.1 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CDJ87113.1 - 0.0069 16.7 0.4 0.013 15.9 0.4 1.7 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 CDJ87113.1 - 0.017 14.6 0.3 0.05 13.1 0.4 1.8 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 CDJ87113.1 - 0.024 15.0 0.1 0.047 14.1 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 CDJ87113.1 - 0.025 14.6 0.0 0.04 13.9 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Glycos_transf_N PF04413.16 CDJ87113.1 - 0.066 12.8 0.1 0.19 11.4 0.1 1.8 2 0 0 2 2 2 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Recep_L_domain PF01030.24 CDJ87115.1 - 7.1e-19 68.0 1.5 6.2e-09 36.0 0.1 3.2 3 0 0 3 3 3 2 Receptor L domain An_peroxidase PF03098.15 CDJ87116.1 - 6.5e-121 404.5 0.0 3.8e-119 398.7 0.0 2.1 2 0 0 2 2 2 2 Animal haem peroxidase Collagen PF01391.18 CDJ87117.1 - 2.2e-27 94.6 95.2 1.3e-10 40.8 31.9 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ87117.1 - 0.007 16.4 0.2 0.012 15.7 0.2 1.4 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Oxysterol_BP PF01237.18 CDJ87118.1 - 7.5e-70 235.6 2.8 4.7e-61 206.7 1.1 2.8 2 1 0 2 2 2 2 Oxysterol-binding protein SCVP PF17619.2 CDJ87119.1 - 0.00042 21.1 0.0 0.00058 20.7 0.0 1.2 1 0 0 1 1 1 1 Secreted clade V proteins Nanovirus_C8 PF05629.11 CDJ87119.1 - 0.059 13.5 0.2 0.079 13.1 0.2 1.2 1 0 0 1 1 1 0 Nanovirus component 8 (C8) protein Cnd1 PF12717.7 CDJ87121.1 - 1.7e-22 80.2 15.2 5e-19 68.9 1.8 4.5 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDJ87121.1 - 2.9e-07 30.8 0.7 0.0093 16.3 0.1 4.4 3 1 1 4 4 4 2 HEAT repeats Cnd3 PF12719.7 CDJ87121.1 - 7.2e-07 28.7 1.9 1.4e-06 27.8 0.2 2.4 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 CDJ87121.1 - 2.8e-06 27.1 10.3 1.6 9.2 0.0 6.5 6 0 0 6 6 6 3 HEAT repeat Adaptin_N PF01602.20 CDJ87121.1 - 0.00086 18.0 6.0 0.04 12.5 1.6 2.8 2 1 1 3 3 3 3 Adaptin N terminal region Cohesin_HEAT PF12765.7 CDJ87121.1 - 0.031 14.6 0.1 2.7 8.4 0.1 3.1 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 CDJ87121.1 - 0.38 11.3 5.0 1.5e+02 3.0 0.0 5.2 5 0 0 5 5 5 0 HEAT-like repeat HTH_48 PF17906.1 CDJ87122.1 - 1e-17 63.9 0.9 2.2e-17 62.9 0.9 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_Tnp_IS630 PF01710.16 CDJ87122.1 - 4.2e-07 30.0 0.0 4.7e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 CDJ87122.1 - 2.3e-06 27.2 0.1 0.014 15.1 0.0 2.5 2 0 0 2 2 2 2 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 CDJ87122.1 - 9.6e-06 25.8 0.6 3.5e-05 24.0 0.3 1.9 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 CDJ87122.1 - 1.4e-05 25.6 0.0 2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 CDJ87122.1 - 2.1e-05 24.2 0.0 4.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 CDJ87122.1 - 4.6e-05 23.5 0.0 0.49 10.6 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_50 PF18024.1 CDJ87122.1 - 0.00023 20.7 0.0 0.00041 19.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 CDJ87122.1 - 0.0014 18.5 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 HTH domain HTH_29 PF13551.6 CDJ87122.1 - 0.0017 18.3 0.0 0.24 11.4 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_1 PF01527.20 CDJ87122.1 - 0.0072 16.6 0.1 4.5 7.7 0.0 2.2 1 1 1 2 2 2 2 Transposase IF2_N PF04760.15 CDJ87122.1 - 0.009 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region TubC_N PF18563.1 CDJ87122.1 - 0.02 14.8 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 TubC N-terminal docking domain HTH_40 PF14493.6 CDJ87122.1 - 0.021 15.3 0.2 0.039 14.4 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_6 PF01418.17 CDJ87122.1 - 0.021 14.8 0.0 0.051 13.6 0.0 1.6 2 0 0 2 2 1 0 Helix-turn-helix domain, rpiR family Terminase_5 PF06056.12 CDJ87122.1 - 0.027 14.3 0.0 4 7.4 0.0 2.3 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_ISL3 PF13542.6 CDJ87122.1 - 0.032 13.6 0.1 0.23 10.9 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_36 PF13730.6 CDJ87122.1 - 0.039 13.9 0.0 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_5 PF01022.20 CDJ87122.1 - 0.043 13.7 0.1 0.069 13.0 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_10 PF04967.12 CDJ87122.1 - 0.048 13.5 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 HTH DNA binding domain GerE PF00196.19 CDJ87122.1 - 0.099 12.2 0.3 0.26 10.9 0.3 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Phage_terminase PF10668.9 CDJ87122.1 - 0.17 11.9 0.2 0.59 10.2 0.0 1.9 2 0 0 2 2 2 0 Phage terminase small subunit Peptidase_C1 PF00112.23 CDJ87123.1 - 3.1e-67 226.9 5.9 4.1e-67 226.4 5.9 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ87123.1 - 0.067 11.9 1.8 0.24 10.1 0.1 2.0 2 0 0 2 2 2 0 Peptidase C1-like family HTH_Tnp_Tc3_2 PF01498.18 CDJ87124.1 - 0.00026 21.2 0.2 0.00037 20.7 0.2 1.2 1 0 0 1 1 1 1 Transposase HTH_IclR PF09339.10 CDJ87124.1 - 0.00087 19.0 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.6 CDJ87124.1 - 0.02 14.4 0.4 0.033 13.8 0.0 1.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Nterm_IS4 PF13006.7 CDJ87124.1 - 0.068 13.4 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 Insertion element 4 transposase N-terminal Peptidase_C1 PF00112.23 CDJ87125.1 - 4.6e-66 223.0 11.1 6.3e-66 222.6 11.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ87125.1 - 0.0035 16.2 2.2 0.034 12.9 0.4 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ87126.1 - 1.2e-68 231.5 5.2 1.4e-68 231.2 5.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ87126.1 - 0.015 14.1 1.2 0.047 12.5 0.2 2.0 2 0 0 2 2 2 0 Peptidase C1-like family ShK PF01549.24 CDJ87127.1 - 0.0014 19.1 5.1 0.0026 18.2 5.1 1.5 1 1 0 1 1 1 1 ShK domain-like PLAC PF08686.11 CDJ87127.1 - 0.033 15.0 1.0 0.07 13.9 1.0 1.6 1 1 0 1 1 1 0 PLAC (protease and lacunin) domain HMG_box_2 PF09011.10 CDJ87128.1 - 0.0014 19.2 0.0 0.0035 17.9 0.0 1.6 1 0 0 1 1 1 1 HMG-box domain WD-3 PF09765.9 CDJ87128.1 - 0.086 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 WD-repeat region Ig_3 PF13927.6 CDJ87130.1 - 2e-06 28.3 0.0 3.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CDJ87130.1 - 1.4e-05 25.3 0.0 2.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CDJ87130.1 - 0.0039 17.3 0.1 0.0078 16.4 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain EGF_2 PF07974.13 CDJ87130.1 - 0.0048 17.2 12.5 0.0083 16.5 12.5 1.4 1 0 0 1 1 1 1 EGF-like domain Ig_5 PF16681.5 CDJ87130.1 - 0.032 14.6 0.2 0.082 13.3 0.1 1.7 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 CDJ87130.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 C17orf99 Ig domain I-set PF07679.16 CDJ87130.1 - 0.16 12.1 0.1 0.79 9.8 0.1 2.0 1 1 0 1 1 1 0 Immunoglobulin I-set domain Plasmod_Pvs28 PF06247.11 CDJ87130.1 - 1.1 9.6 5.1 3.3 8.1 5.1 1.9 1 0 0 1 1 1 0 Pvs28 EGF domain Fibrinogen_C PF00147.18 CDJ87131.1 - 1.7e-43 149.0 6.8 3.1e-43 148.1 6.8 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Lectin_C PF00059.21 CDJ87131.1 - 2.1e-11 44.5 9.5 2.1e-11 44.5 9.5 2.9 3 1 1 4 4 4 1 Lectin C-type domain UL45 PF05473.12 CDJ87131.1 - 0.039 13.6 5.1 0.038 13.6 3.8 1.6 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like PDZ PF00595.24 CDJ87132.1 - 3.6e-05 24.0 0.0 6.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDJ87132.1 - 0.00072 19.4 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Mucin PF01456.17 CDJ87133.1 - 0.56 10.2 15.3 1.2 9.1 15.3 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Sema PF01403.19 CDJ87134.1 - 6.1e-27 94.5 0.2 1.2e-25 90.2 0.0 2.6 2 1 0 2 2 2 1 Sema domain TIG_2 PF18020.1 CDJ87134.1 - 1.2e-12 48.3 0.0 1.3e-10 41.7 0.0 2.5 2 0 0 2 2 2 1 TIG domain found in plexin PSI PF01437.25 CDJ87134.1 - 1.1e-10 41.9 40.3 1.4e-05 25.6 12.9 3.8 3 0 0 3 3 3 2 Plexin repeat TIG_plexin PF17960.1 CDJ87134.1 - 4.9e-09 36.1 0.1 2.3e-05 24.3 0.0 2.9 2 0 0 2 2 2 2 TIG domain Roc PF08477.13 CDJ87135.1 - 4.5e-05 23.7 0.0 7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDJ87135.1 - 0.0021 17.7 0.0 0.0024 17.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.21 CDJ87135.1 - 0.0028 17.2 0.1 0.0033 16.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Amidase PF01425.21 CDJ87136.1 - 4.8e-62 210.4 0.0 1.1e-61 209.2 0.0 1.6 1 1 0 1 1 1 1 Amidase Amidase PF01425.21 CDJ87137.1 - 7.5e-72 242.7 0.0 3.2e-71 240.6 0.0 1.8 1 1 0 1 1 1 1 Amidase His_Phos_1 PF00300.22 CDJ87138.1 - 1.6e-10 41.0 0.0 4.2e-10 39.6 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Collagen PF01391.18 CDJ87139.1 - 2.6e-26 91.1 85.5 3.4e-11 42.7 32.3 3.8 2 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ87139.1 - 4.5e-06 26.6 0.7 5.6e-06 26.3 0.7 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ87140.1 - 2.5e-25 88.0 82.3 0.00046 19.9 11.8 4.3 2 1 0 2 2 2 2 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ87140.1 - 8.9e-07 28.9 0.6 1.2e-06 28.4 0.6 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain NTP_transf_6 PF06042.11 CDJ87141.1 - 0.0019 18.1 0.4 0.0021 18.0 0.4 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase Inhibitor_I10 PF12559.8 CDJ87141.1 - 0.0059 16.8 0.1 0.0084 16.3 0.1 1.3 1 0 0 1 1 1 1 Serine endopeptidase inhibitors TIP41 PF04176.13 CDJ87142.1 - 2.6e-53 180.0 0.0 3.5e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 TIP41-like family HTH_26 PF13443.6 CDJ87143.1 - 0.0002 21.7 0.1 0.00041 20.7 0.1 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_IclR PF09339.10 CDJ87143.1 - 0.0027 17.5 0.0 0.0048 16.7 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 CDJ87143.1 - 0.0076 16.1 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_Tnp_ISL3 PF13542.6 CDJ87143.1 - 0.02 14.3 0.1 0.05 13.0 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.6 CDJ87143.1 - 0.02 14.4 0.0 0.05 13.2 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding CENP-B_N PF04218.13 CDJ87143.1 - 0.028 14.1 0.0 0.068 12.8 0.0 1.7 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain DUF3602 PF12223.8 CDJ87143.1 - 0.029 15.0 0.3 0.06 14.0 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) HTH_3 PF01381.22 CDJ87143.1 - 0.04 14.0 0.0 0.082 13.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix LacI PF00356.21 CDJ87143.1 - 0.049 13.4 0.1 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_10 PF04967.12 CDJ87143.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain Nitroreductase PF00881.24 CDJ87144.1 - 7.1e-22 78.3 0.0 1.2e-21 77.5 0.0 1.4 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 CDJ87144.1 - 3.5e-06 26.7 0.4 0.094 12.3 0.0 3.2 2 1 1 3 3 3 2 Putative TM nitroreductase DUF3255 PF11631.8 CDJ87144.1 - 0.14 12.1 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3255) HTH_50 PF18024.1 CDJ87146.1 - 0.0099 15.5 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain STAR_dimer PF16544.5 CDJ87147.1 - 2.8e-07 30.0 0.0 7.1e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Homodimerisation region of STAR domain protein KH_1 PF00013.29 CDJ87147.1 - 1e-06 28.4 0.0 2.5e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 KH domain MoaE PF02391.17 CDJ87147.1 - 0.062 13.6 0.4 3.5 7.9 0.2 2.3 2 0 0 2 2 2 0 MoaE protein DUF2034 PF10356.9 CDJ87147.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2034) BAR PF03114.18 CDJ87148.1 - 4.5e-38 131.2 10.6 6.7e-38 130.7 10.6 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 CDJ87148.1 - 1.2e-11 44.3 0.1 2.3e-11 43.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDJ87148.1 - 3.5e-09 36.1 0.0 6.9e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDJ87148.1 - 4e-08 32.8 0.0 6.8e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 CDJ87148.1 - 6e-05 22.9 4.9 6e-05 22.9 4.9 1.8 2 0 0 2 2 2 1 BAR domain of APPL family COG5 PF10392.9 CDJ87148.1 - 0.016 15.4 3.7 0.017 15.3 0.2 2.5 2 1 0 2 2 2 0 Golgi transport complex subunit 5 ApoL PF05461.11 CDJ87148.1 - 0.24 10.7 1.8 0.34 10.2 0.7 1.8 1 1 1 2 2 2 0 Apolipoprotein L Prominin PF05478.11 CDJ87148.1 - 0.29 9.0 2.1 0.57 8.1 1.3 1.6 1 1 1 2 2 2 0 Prominin Arfaptin PF06456.13 CDJ87148.1 - 0.43 10.1 7.0 2.1 7.9 7.0 2.1 1 1 0 1 1 1 0 Arfaptin-like domain DUF5633 PF18656.1 CDJ87148.1 - 0.59 10.1 0.0 0.59 10.1 0.0 2.6 4 0 0 4 4 4 0 Family of unknown function (DUF5633) ASC PF00858.24 CDJ87149.1 - 2.9e-17 62.8 0.1 3.9e-17 62.4 0.1 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel MadM PF03818.13 CDJ87149.1 - 0.041 13.7 0.3 0.066 13.1 0.3 1.3 1 0 0 1 1 1 0 Malonate/sodium symporter MadM subunit P4Ha_N PF08336.11 CDJ87150.1 - 1.7e-39 134.9 1.3 3.1e-39 134.1 0.4 1.9 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 CDJ87150.1 - 1.1e-13 51.9 0.1 1.9e-13 51.1 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ANAPC3 PF12895.7 CDJ87150.1 - 4.4e-05 23.6 1.6 0.015 15.5 0.2 2.9 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CDJ87150.1 - 8.8e-05 22.3 3.7 0.00021 21.2 1.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ87150.1 - 0.0044 17.5 0.4 0.012 16.2 0.4 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ87150.1 - 0.009 16.8 0.5 0.009 16.8 0.5 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ87150.1 - 0.012 16.2 4.2 0.017 15.8 0.8 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat YfiO PF13525.6 CDJ87150.1 - 0.017 14.9 1.4 0.036 13.8 0.4 2.0 2 0 0 2 2 2 0 Outer membrane lipoprotein TPR_6 PF13174.6 CDJ87150.1 - 0.067 13.9 0.4 0.33 11.7 0.4 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C2H2 PF00096.26 CDJ87152.1 - 0.0087 16.5 3.9 0.0087 16.5 3.9 3.0 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-C2HE PF16278.5 CDJ87152.1 - 0.45 11.0 4.1 10 6.7 0.2 2.9 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_2 PF13465.6 CDJ87152.1 - 8 7.1 11.7 0.89 10.1 2.8 3.0 3 0 0 3 3 3 0 Zinc-finger double domain I-set PF07679.16 CDJ87153.1 - 1.3e-12 47.6 0.0 1.7e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ87153.1 - 8.8e-07 29.4 0.0 1.4e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain TPR_12 PF13424.6 CDJ87154.1 - 3e-08 33.9 1.6 1.9e-07 31.3 0.4 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ87154.1 - 1.8e-05 24.3 3.4 1.3 9.0 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ87154.1 - 3e-05 23.6 0.6 0.37 10.5 0.1 3.5 3 0 0 3 3 3 3 TPR repeat TPR_8 PF13181.6 CDJ87154.1 - 9.9e-05 22.3 1.1 7.3 7.1 0.1 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ87154.1 - 0.0045 17.0 2.0 4.7 7.6 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ87154.1 - 0.067 13.3 0.2 53 4.2 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat adh_short PF00106.25 CDJ87155.1 - 5.4e-36 123.9 0.0 9.7e-36 123.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ87155.1 - 6.7e-21 74.9 0.0 1.1e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ87155.1 - 0.0073 16.2 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Serpin PF00079.20 CDJ87156.1 - 4e-50 171.2 0.1 5e-50 170.9 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) p450 PF00067.22 CDJ87159.1 - 7.5e-89 298.6 0.1 7.5e-89 298.6 0.1 2.0 3 0 0 3 3 3 1 Cytochrome P450 DUF4401 PF14351.6 CDJ87159.1 - 0.53 9.5 1.4 0.77 9.0 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) PI3_PI4_kinase PF00454.27 CDJ87160.1 - 9.1e-44 150.1 0.1 2.6e-41 142.1 0.1 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PA28_beta PF02252.18 CDJ87160.1 - 2.4e-31 108.3 0.1 5.8e-31 107.1 0.1 1.6 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PI3Ka PF00613.20 CDJ87160.1 - 6e-23 81.2 0.0 1.4e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) IZUMO PF15005.6 CDJ87160.1 - 0.012 16.1 0.5 12 6.4 0.0 3.4 2 1 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated DUF4135 PF13575.6 CDJ87160.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Guanylate_cyc PF00211.20 CDJ87161.1 - 1.6e-63 213.6 0.0 2.6e-63 212.9 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase PF00069.25 CDJ87161.1 - 1.7e-14 53.8 0.0 2.8e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ87161.1 - 1.8e-13 50.4 0.0 2.7e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ANF_receptor PF01094.28 CDJ87161.1 - 6.7e-07 28.7 0.0 1.1e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Receptor family ligand binding region HNOBA PF07701.14 CDJ87161.1 - 1.8e-06 27.6 0.9 3e-06 26.8 0.9 1.3 1 0 0 1 1 1 1 Heme NO binding associated RE_ApaLI PF09499.10 CDJ87161.1 - 0.14 11.9 0.2 0.24 11.1 0.2 1.3 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease CAP PF00188.26 CDJ87162.1 - 7.5e-17 62.3 2.2 9.9e-17 62.0 2.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF3630 PF12305.8 CDJ87162.1 - 0.2 11.8 1.0 15 5.7 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3630) CAP PF00188.26 CDJ87163.1 - 4.9e-14 53.2 1.3 6.7e-14 52.8 1.3 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF1451 PF07295.11 CDJ87164.1 - 2.6 8.1 5.6 6.5 6.8 3.3 2.6 2 1 0 2 2 2 0 Zinc-ribbon containing domain Peptidase_M13_N PF05649.13 CDJ87165.1 - 1.6e-31 110.4 0.5 3.7e-31 109.2 0.3 1.7 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.21 CDJ87165.1 - 0.011 15.4 0.1 0.049 13.2 0.0 2.0 1 1 1 2 2 2 0 Peptidase family M13 Pkinase PF00069.25 CDJ87166.1 - 4.8e-06 26.1 0.0 1.1e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain HTH_psq PF05225.16 CDJ87167.1 - 2.6e-25 87.9 0.8 1.6e-13 50.2 0.0 2.8 3 0 0 3 3 3 2 helix-turn-helix, Psq domain Enkurin PF13864.6 CDJ87168.1 - 0.0095 16.4 1.4 0.0095 16.4 1.4 3.5 4 0 0 4 4 4 1 Calmodulin-binding Phosphodiest PF01663.22 CDJ87169.1 - 1.5e-51 176.1 0.3 1.8e-51 175.8 0.3 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CDJ87169.1 - 0.0062 16.0 0.1 0.03 13.7 0.1 1.8 1 1 1 2 2 2 1 Sulfatase Acetyltransf_18 PF18014.1 CDJ87170.1 - 7.1e-05 22.6 0.0 0.00039 20.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Rad10 PF03834.14 CDJ87170.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) RNase_II_C_S1 PF18614.1 CDJ87170.1 - 0.11 12.4 0.0 0.55 10.2 0.0 2.1 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain YukC PF10140.9 CDJ87170.1 - 0.13 11.1 0.1 12 4.6 0.0 2.2 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC Ig_3 PF13927.6 CDJ87171.1 - 5.6e-64 212.7 11.2 1.4e-10 41.6 0.2 7.8 7 0 0 7 7 7 7 Immunoglobulin domain Ig_2 PF13895.6 CDJ87171.1 - 8.2e-50 167.1 12.4 1.1e-09 38.4 0.1 8.2 7 1 0 7 7 7 6 Immunoglobulin domain I-set PF07679.16 CDJ87171.1 - 3.6e-49 164.8 5.9 3.6e-09 36.6 0.0 9.5 7 3 0 7 7 7 6 Immunoglobulin I-set domain ig PF00047.25 CDJ87171.1 - 8.2e-42 141.3 3.3 6.2e-09 35.9 0.2 8.2 8 1 0 8 8 8 5 Immunoglobulin domain V-set PF07686.17 CDJ87171.1 - 2.7e-17 62.9 20.4 0.0016 18.6 0.3 9.6 8 4 1 9 9 9 6 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDJ87171.1 - 1.5e-15 57.0 6.0 3.2e-10 39.9 0.2 5.0 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.11 CDJ87171.1 - 9.8e-08 32.1 10.1 0.0058 16.6 0.0 6.4 7 1 1 8 8 8 2 CD47 immunoglobulin-like domain Ig_6 PF18452.1 CDJ87171.1 - 4.3e-07 29.4 0.0 0.99 9.0 0.0 6.2 6 0 0 6 6 6 2 Immunoglobulin domain Ig_5 PF16681.5 CDJ87171.1 - 5.1e-07 30.0 0.2 1.8 9.0 0.0 6.3 7 0 0 7 7 7 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain fn3 PF00041.21 CDJ87171.1 - 8.4e-07 29.2 1.8 6.9e-05 23.1 0.1 3.5 3 1 0 3 3 2 1 Fibronectin type III domain Izumo-Ig PF16706.5 CDJ87171.1 - 0.00046 20.2 1.7 1.1 9.3 0.0 5.2 6 0 0 6 6 6 1 Izumo-like Immunoglobulin domain TMEM154 PF15102.6 CDJ87171.1 - 0.00087 19.2 0.6 0.002 18.0 0.0 2.0 2 0 0 2 2 1 1 TMEM154 protein family Pur_ac_phosph_N PF16656.5 CDJ87171.1 - 0.0099 16.4 0.1 0.12 12.9 0.0 2.8 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain DUF2093 PF09866.9 CDJ87171.1 - 0.016 14.7 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) TMEM52 PF14979.6 CDJ87171.1 - 0.024 14.6 0.3 0.057 13.3 0.3 1.6 1 0 0 1 1 1 0 Transmembrane 52 Shisa PF13908.6 CDJ87171.1 - 0.041 14.1 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Sarcoglycan_2 PF05510.13 CDJ87171.1 - 0.047 12.5 0.0 0.46 9.2 0.0 2.0 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon L_HMGIC_fpl PF10242.9 CDJ87171.1 - 0.054 13.7 0.3 0.12 12.6 0.3 1.5 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein EphA2_TM PF14575.6 CDJ87171.1 - 0.13 13.2 0.0 0.42 11.5 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain IQ PF00612.27 CDJ87172.1 - 4.1e-22 75.9 1.1 4.4e-07 29.1 0.1 3.5 3 0 0 3 3 3 3 IQ calmodulin-binding motif RIIa PF02197.17 CDJ87172.1 - 4.7e-10 39.0 0.5 7.4e-10 38.3 0.5 1.3 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DUF1771 PF08590.10 CDJ87172.1 - 0.11 12.9 0.6 0.25 11.7 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) WD40 PF00400.32 CDJ87173.1 - 4.5e-08 33.6 0.3 0.0017 19.1 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat WD40_like PF17005.5 CDJ87173.1 - 0.00012 21.5 0.4 0.0094 15.3 0.3 2.5 1 1 0 1 1 1 1 WD40-like domain RAB3GAP2_N PF14655.6 CDJ87173.1 - 0.00023 20.6 2.3 0.023 14.0 0.1 3.0 2 1 0 3 3 3 2 Rab3 GTPase-activating protein regulatory subunit N-terminus Mcl1_mid PF12341.8 CDJ87173.1 - 0.002 17.5 1.9 0.031 13.6 0.0 2.8 2 1 0 3 3 3 1 Minichromosome loss protein, Mcl1, middle region Pkinase_Tyr PF07714.17 CDJ87174.1 - 9.2e-95 316.8 0.0 2e-94 315.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase I-set PF07679.16 CDJ87174.1 - 1.6e-40 137.1 0.0 3.8e-13 49.3 0.0 3.7 3 1 0 3 3 3 3 Immunoglobulin I-set domain Pkinase PF00069.25 CDJ87174.1 - 4.6e-40 137.6 0.0 1.6e-37 129.3 0.0 3.1 2 1 0 2 2 2 1 Protein kinase domain Ig_3 PF13927.6 CDJ87174.1 - 7.4e-36 122.6 0.0 1.2e-11 45.1 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 CDJ87174.1 - 5.1e-27 93.9 0.1 6.2e-08 32.7 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 CDJ87174.1 - 2e-25 88.9 0.1 1.1e-09 38.5 0.0 3.9 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 CDJ87174.1 - 6.3e-17 61.7 1.4 0.0001 22.4 0.1 5.3 3 2 0 3 3 3 3 Immunoglobulin V-set domain Ig_5 PF16681.5 CDJ87174.1 - 2.7e-07 30.9 0.0 0.21 12.0 0.0 3.9 3 0 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Receptor_2B4 PF11465.8 CDJ87174.1 - 1.2e-06 28.7 0.0 0.0036 17.5 0.0 3.2 2 0 0 2 2 2 2 Natural killer cell receptor 2B4 Ig_4 PF16680.5 CDJ87174.1 - 1.6e-06 28.2 0.0 0.41 11.0 0.0 3.9 3 2 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 CDJ87174.1 - 2.1e-05 24.5 0.1 0.0031 17.5 0.1 3.4 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 CDJ87174.1 - 2.9e-05 24.0 1.8 0.16 12.0 0.0 3.3 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 CDJ87174.1 - 0.00078 19.8 0.0 0.1 13.0 0.0 2.7 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Ig_6 PF18452.1 CDJ87174.1 - 0.00083 18.9 0.0 3.9 7.1 0.0 3.6 3 0 0 3 3 3 1 Immunoglobulin domain TMEM52 PF14979.6 CDJ87174.1 - 0.083 12.8 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Transmembrane 52 Adeno_E3_CR1 PF02440.15 CDJ87174.1 - 0.088 12.6 0.4 0.47 10.3 0.2 2.3 3 0 0 3 3 3 0 Adenovirus E3 region protein CR1 Haspin_kinase PF12330.8 CDJ87174.1 - 0.61 9.0 2.1 0.43 9.5 0.4 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Hint PF01079.20 CDJ87175.1 - 5.5e-49 166.6 0.0 8.9e-49 165.9 0.0 1.2 1 0 0 1 1 1 1 Hint module Hint_2 PF13403.6 CDJ87175.1 - 0.064 13.6 0.0 0.16 12.2 0.0 1.7 1 1 0 1 1 1 0 Hint domain Arabinose_Isome PF02610.15 CDJ87175.1 - 0.16 11.1 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 L-arabinose isomerase 2HCT PF03390.15 CDJ87176.1 - 0.021 13.4 0.0 0.024 13.2 0.0 1.0 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family DUF2046 PF09755.9 CDJ87177.1 - 1.1e-48 166.0 32.9 1.9e-48 165.3 31.7 1.7 1 1 1 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) Tho2 PF11262.8 CDJ87177.1 - 0.0031 16.7 0.1 0.0031 16.7 0.1 3.3 2 1 1 3 3 3 1 Transcription factor/nuclear export subunit protein 2 JIP_LZII PF16471.5 CDJ87177.1 - 0.032 14.4 1.8 0.032 14.4 1.8 5.1 3 2 1 4 4 4 0 JNK-interacting protein leucine zipper II PRTase_1 PF11202.8 CDJ87177.1 - 0.12 11.5 2.2 0.28 10.4 2.2 1.7 1 0 0 1 1 1 0 Phosphoribosyl transferase (PRTase) TMF_TATA_bd PF12325.8 CDJ87177.1 - 0.93 9.7 39.8 0.25 11.6 2.8 4.1 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding LPP PF04728.13 CDJ87177.1 - 6.6 7.2 11.0 14 6.2 0.2 4.5 4 0 0 4 4 4 0 Lipoprotein leucine-zipper GATase_2 PF00310.21 CDJ87178.1 - 6.8e-156 519.2 0.0 8.3e-156 518.9 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DUF1586 PF07625.11 CDJ87180.1 - 0.6 10.2 2.7 1.2 9.2 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1586) FARP PF01581.16 CDJ87181.1 - 0.09 13.3 3.4 11 7.1 0.1 2.7 2 1 0 2 2 2 0 FMRFamide related peptide family DUF2207 PF09972.9 CDJ87181.1 - 0.12 11.1 0.0 0.14 10.9 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Glu_synthase PF01645.17 CDJ87182.1 - 2.7e-159 530.2 0.6 3.9e-156 519.8 0.1 2.2 2 0 0 2 2 2 2 Conserved region in glutamate synthase Glu_syn_central PF04898.14 CDJ87182.1 - 2.4e-103 345.5 0.0 8.1e-102 340.4 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 CDJ87182.1 - 9.7e-75 250.3 1.2 2e-74 249.3 1.2 1.5 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 CDJ87182.1 - 3.9e-25 88.7 0.4 1.8e-24 86.5 0.4 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 CDJ87182.1 - 8.1e-21 73.9 0.7 2.3e-20 72.4 0.7 1.8 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 CDJ87182.1 - 1.6e-08 34.6 0.1 7.7e-08 32.5 0.1 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CDJ87182.1 - 4.5e-08 33.5 1.6 9e-05 23.0 0.6 3.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CDJ87182.1 - 6.2e-06 25.8 0.1 1.4e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CDJ87182.1 - 1.1e-05 24.3 1.9 0.00023 20.0 0.4 3.0 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 CDJ87182.1 - 5.1e-05 22.7 1.4 0.0037 16.6 0.1 3.3 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 CDJ87182.1 - 7.3e-05 22.2 0.1 0.00017 21.0 0.1 1.6 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase GATase_2 PF00310.21 CDJ87182.1 - 8.9e-05 21.4 0.0 0.00015 20.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DAO PF01266.24 CDJ87182.1 - 0.00036 20.2 4.2 0.043 13.4 0.8 3.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 CDJ87182.1 - 0.00056 19.3 0.6 0.87 8.8 0.4 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 CDJ87182.1 - 0.001 18.2 1.4 0.0024 17.0 1.4 1.6 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 CDJ87182.1 - 0.0011 18.3 0.0 0.0036 16.6 0.1 1.8 2 0 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.19 CDJ87182.1 - 0.0017 17.7 0.0 0.085 12.2 0.1 2.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 CDJ87182.1 - 0.0055 16.0 1.5 0.019 14.2 0.6 2.1 2 0 0 2 2 2 1 FAD binding domain FMN_dh PF01070.18 CDJ87182.1 - 0.015 14.4 0.4 0.028 13.4 0.4 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase NAD_binding_7 PF13241.6 CDJ87182.1 - 0.021 15.2 1.0 0.58 10.6 0.1 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.22 CDJ87182.1 - 0.021 13.9 0.0 0.046 12.8 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A FMO-like PF00743.19 CDJ87182.1 - 0.035 12.5 0.0 0.24 9.8 0.0 2.1 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like AdoHcyase_NAD PF00670.21 CDJ87182.1 - 0.058 13.5 0.9 67 3.5 0.0 3.7 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PG_binding_2 PF08823.11 CDJ87182.1 - 0.11 12.8 0.5 1.6 9.1 0.4 2.6 2 0 0 2 2 2 0 Putative peptidoglycan binding domain TFIIA PF03153.13 CDJ87182.1 - 1.3 9.0 12.0 2.3 8.1 12.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING_10 PF16685.5 CDJ87184.1 - 0.024 14.8 9.8 0.48 10.6 3.6 2.7 2 0 0 2 2 2 0 zinc RING finger of MSL2 PHD PF00628.29 CDJ87185.1 - 0.00069 19.5 6.9 0.0016 18.3 6.9 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CDJ87185.1 - 1.4 8.6 3.5 3.6 7.2 3.5 1.8 1 0 0 1 1 1 0 PHD-finger Ank_2 PF12796.7 CDJ87188.1 - 1.2e-14 54.7 0.1 3.3e-14 53.2 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ87188.1 - 1.3e-12 48.0 0.0 1.3e-09 38.4 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ87188.1 - 5.1e-11 41.8 0.0 0.0043 17.4 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat BRCT_2 PF16589.5 CDJ87188.1 - 2.4e-09 37.5 1.7 3.2e-05 24.2 0.0 3.8 4 0 0 4 4 3 2 BRCT domain, a BRCA1 C-terminus domain Ank_5 PF13857.6 CDJ87188.1 - 4.4e-09 36.4 0.1 0.006 16.9 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CDJ87188.1 - 1.6e-07 31.4 0.0 0.00084 19.7 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat BRCT PF00533.26 CDJ87188.1 - 0.00013 22.3 0.0 0.59 10.5 0.0 3.7 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain zf-C3HC4_2 PF13923.6 CDJ87188.1 - 0.0012 18.6 4.5 0.0041 16.9 4.5 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ87188.1 - 0.0014 18.6 2.3 0.0055 16.7 2.3 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDJ87188.1 - 0.006 16.7 3.1 0.018 15.2 3.1 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CDJ87188.1 - 0.023 14.6 12.5 0.12 12.3 12.5 2.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 CDJ87188.1 - 0.026 14.4 9.5 0.081 12.8 9.5 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) BRCT_3 PF18428.1 CDJ87188.1 - 0.072 13.2 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CDJ87188.1 - 0.16 12.3 0.9 22 5.5 0.0 3.4 4 0 0 4 4 3 0 DNA ligase 3 BRCT domain zf-rbx1 PF12678.7 CDJ87188.1 - 0.52 10.6 8.9 2.2 8.6 8.9 2.1 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CDJ87188.1 - 3.5 7.5 9.1 14 5.7 9.1 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 IBR PF01485.21 CDJ87188.1 - 4.1 7.7 11.8 31 4.9 11.9 2.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Patched PF02460.18 CDJ87189.1 - 6.1e-159 530.7 0.6 7.3e-159 530.4 0.6 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 CDJ87189.1 - 5.7e-37 126.9 3.4 1.1e-36 125.9 3.4 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 CDJ87189.1 - 0.00021 20.4 2.9 0.0004 19.4 2.9 1.4 1 0 0 1 1 1 1 MMPL family DUF3087 PF11286.8 CDJ87190.1 - 0.014 14.9 6.6 0.2 11.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3087) DUF816 PF05674.12 CDJ87190.1 - 0.015 15.2 0.5 0.015 15.2 0.5 2.0 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF816) Alpha_Helical PF18489.1 CDJ87190.1 - 0.031 14.4 1.5 0.12 12.5 1.5 2.0 1 0 0 1 1 1 0 Alpha helical domain PAS_7 PF12860.7 CDJ87190.1 - 0.26 11.5 3.8 22 5.3 0.6 3.3 2 1 0 2 2 2 0 PAS fold Z1 PF10593.9 CDJ87190.1 - 0.58 9.6 14.9 0.02 14.4 3.1 2.9 1 1 1 3 3 3 0 Z1 domain Swi5 PF07061.11 CDJ87190.1 - 0.58 10.3 8.1 2.7 8.1 0.2 4.3 4 0 0 4 4 4 0 Swi5 ERp29 PF07749.12 CDJ87190.1 - 1.1 10.2 7.6 1.6 9.7 3.9 3.2 2 1 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain KxDL PF10241.9 CDJ87190.1 - 1.3 9.4 19.5 10 6.5 0.5 6.0 4 2 1 6 6 6 0 Uncharacterized conserved protein DUF4472 PF14739.6 CDJ87190.1 - 1.5 9.6 16.5 2.5 8.9 1.2 3.2 3 0 0 3 3 2 0 Domain of unknown function (DUF4472) HR1 PF02185.16 CDJ87190.1 - 1.5 9.0 10.6 6.6 6.9 0.8 4.3 4 0 0 4 4 4 0 Hr1 repeat Syntaxin-6_N PF09177.11 CDJ87190.1 - 7.6 7.2 17.5 26 5.4 0.0 5.1 2 1 2 4 4 3 0 Syntaxin 6, N-terminal Patched PF02460.18 CDJ87191.1 - 2.3e-77 260.8 9.9 2.6e-77 260.7 9.9 1.0 1 0 0 1 1 1 1 Patched family SecD_SecF PF02355.16 CDJ87191.1 - 6e-06 25.8 6.8 8.3e-06 25.3 6.8 1.2 1 0 0 1 1 1 1 Protein export membrane protein SNAPc_SNAP43 PF09808.9 CDJ87192.1 - 7.8e-31 107.5 0.0 1.2e-30 106.9 0.0 1.3 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 MOLO1 PF17175.4 CDJ87193.1 - 1.7e-27 95.9 0.1 4.6e-27 94.5 0.0 1.7 2 0 0 2 2 2 1 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 CDJ87193.1 - 0.0095 16.1 0.0 0.08 13.1 0.0 2.0 2 0 0 2 2 2 1 TPM domain Shisa PF13908.6 CDJ87193.1 - 0.026 14.8 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Lipase_GDSL PF00657.22 CDJ87196.1 - 1.6e-14 54.4 0.0 2.4e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 CDJ87196.1 - 3.1e-05 24.4 0.0 8.8e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ANAPC4_WD40 PF12894.7 CDJ87197.1 - 4e-07 30.2 0.1 1 9.7 0.0 5.6 3 1 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 CDJ87197.1 - 0.00019 21.3 0.0 1.3 9.0 0.0 4.3 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat WD40 PF00400.32 CDJ87197.1 - 0.0084 16.9 0.0 41 5.3 0.0 5.0 5 0 0 5 5 5 0 WD domain, G-beta repeat CPSF_A PF03178.15 CDJ87197.1 - 0.02 14.2 0.0 0.071 12.4 0.0 1.8 2 0 0 2 2 2 0 CPSF A subunit region SdiA-regulated PF06977.11 CDJ87197.1 - 0.036 13.3 0.0 9.1 5.4 0.0 2.4 2 0 0 2 2 2 0 SdiA-regulated Gmad1 PF10647.9 CDJ87197.1 - 0.14 11.9 4.0 0.69 9.6 0.3 2.6 1 1 2 3 3 3 0 Lipoprotein LpqB beta-propeller domain dCMP_cyt_deam_1 PF00383.23 CDJ87198.1 - 2.1e-23 82.1 0.7 2.5e-23 81.8 0.7 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CDJ87198.1 - 1.6e-20 73.3 0.1 1.7e-20 73.1 0.1 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 CDJ87198.1 - 0.005 16.9 0.2 0.0078 16.3 0.2 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 CDJ87198.1 - 0.088 12.9 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 APOBEC2 NAD2 PF18782.1 CDJ87198.1 - 0.12 12.5 0.1 0.17 12.0 0.1 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 DUF4147 PF13660.6 CDJ87199.1 - 4.8e-51 173.5 0.1 1.1e-29 103.6 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4147) MOFRL PF05161.13 CDJ87199.1 - 1.7e-30 105.4 0.0 3.5e-30 104.4 0.0 1.6 1 0 0 1 1 1 1 MOFRL family Adap_comp_sub PF00928.21 CDJ87200.1 - 2.4e-29 102.5 0.2 3.3e-29 102.1 0.2 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CDJ87200.1 - 5.6e-05 23.1 0.1 9.1e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF2207 PF09972.9 CDJ87200.1 - 0.024 13.4 0.0 0.046 12.5 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) bMG10 PF17973.1 CDJ87200.1 - 0.067 13.4 0.1 0.45 10.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial Alpha-2-macroglobulin MG10 domain Acetyltransf_1 PF00583.25 CDJ87201.1 - 4.6e-15 55.9 0.1 6.1e-15 55.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDJ87201.1 - 1.3e-08 34.8 0.0 1.7e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDJ87201.1 - 2.3e-07 31.2 0.0 3.2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDJ87201.1 - 4.1e-05 23.5 0.0 7.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 CDJ87201.1 - 0.0049 17.5 0.0 0.0062 17.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CDJ87201.1 - 0.07 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Orai-1 PF07856.12 CDJ87202.1 - 1.5e-48 164.8 6.7 1.9e-48 164.4 6.7 1.1 1 0 0 1 1 1 1 Mediator of CRAC channel activity DUF3007 PF11460.8 CDJ87202.1 - 0.022 15.0 0.4 0.049 13.9 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) Sin_N PF04801.13 CDJ87203.1 - 8.6e-85 285.5 0.0 1.1e-84 285.2 0.0 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region zf-CDGSH PF09360.10 CDJ87204.1 - 1.9e-21 76.0 1.9 1.2e-09 38.2 0.2 2.3 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type GDNF PF02351.16 CDJ87204.1 - 0.0069 17.3 0.4 0.63 11.0 0.0 2.1 2 0 0 2 2 2 2 GDNF/GAS1 domain Sushi PF00084.20 CDJ87206.1 - 2.2e-46 156.2 55.0 7.2e-06 26.5 0.1 12.3 12 0 0 12 12 12 11 Sushi repeat (SCR repeat) TYA PF01021.19 CDJ87206.1 - 0.03 14.6 0.6 0.094 13.1 0.3 1.9 2 0 0 2 2 2 0 TYA transposon protein CBM_14 PF01607.24 CDJ87206.1 - 0.22 11.7 0.1 0.22 11.7 0.1 7.5 8 0 0 8 8 8 0 Chitin binding Peritrophin-A domain Sushi PF00084.20 CDJ87207.1 - 6.5e-13 49.1 2.8 0.0016 19.0 0.0 3.3 3 0 0 3 3 3 3 Sushi repeat (SCR repeat) SH3_19 PF18597.1 CDJ87207.1 - 0.013 15.3 0.4 0.04 13.7 0.1 2.0 2 0 0 2 2 2 0 Myosin X N-terminal SH3 domain JAB PF01398.21 CDJ87208.1 - 1.5e-32 112.0 0.1 1.5e-32 112.0 0.1 2.5 2 1 1 3 3 3 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CDJ87208.1 - 1.7e-31 109.0 0.6 3.6e-31 107.9 0.6 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Connexin PF00029.19 CDJ87208.1 - 0.028 14.2 6.4 0.05 13.3 6.4 1.4 1 1 0 1 1 1 0 Connexin TERB2 PF15101.6 CDJ87208.1 - 0.034 14.2 3.1 0.059 13.4 3.1 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 RNA_pol_Rpc4 PF05132.14 CDJ87208.1 - 0.12 12.8 5.3 0.18 12.2 5.3 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 CobT PF06213.12 CDJ87208.1 - 0.42 10.0 8.2 0.7 9.2 8.2 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 CDJ87208.1 - 0.75 8.0 8.5 1.1 7.5 8.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Ureide_permease PF07168.11 CDJ87208.1 - 1.3 7.7 6.6 1.9 7.1 6.6 1.2 1 0 0 1 1 1 0 Ureide permease FAM176 PF14851.6 CDJ87208.1 - 1.6 8.3 4.7 2.9 7.5 4.7 1.4 1 0 0 1 1 1 0 FAM176 family Eapp_C PF10238.9 CDJ87208.1 - 1.8 8.6 7.5 3.1 7.9 7.5 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein YqfQ PF14181.6 CDJ87208.1 - 2.3 8.4 8.5 3.8 7.7 8.5 1.3 1 0 0 1 1 1 0 YqfQ-like protein Presenilin PF01080.17 CDJ87208.1 - 5.4 5.7 4.9 6.9 5.3 4.9 1.1 1 0 0 1 1 1 0 Presenilin FKBP_C PF00254.28 CDJ87209.1 - 2.9e-08 33.9 0.0 6.4e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 CDJ87209.1 - 0.021 14.7 0.1 0.038 13.8 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ87209.1 - 0.13 12.5 0.2 0.3 11.3 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Kelch_1 PF01344.25 CDJ87210.1 - 2.6e-20 71.7 0.8 5.3e-12 45.1 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 CDJ87210.1 - 5.2e-14 52.0 0.0 2.9e-05 24.2 0.0 3.1 2 1 1 3 3 3 3 Kelch motif Kelch_2 PF07646.15 CDJ87210.1 - 3.7e-09 36.2 0.3 2.7e-05 23.9 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 CDJ87210.1 - 0.02 14.9 0.2 2.2 8.3 0.1 2.9 3 1 0 3 3 3 0 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ87210.1 - 0.062 13.6 0.5 5.9 7.3 0.0 2.7 2 1 1 3 3 3 0 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ87210.1 - 0.1 12.7 0.0 0.28 11.2 0.0 1.8 2 0 0 2 2 2 0 Kelch motif Peptidase_A17 PF05380.13 CDJ87211.1 - 5e-05 23.4 2.1 5.5e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Pao retrotransposon peptidase FUSC PF04632.12 CDJ87211.1 - 1.7 7.1 8.5 2.2 6.7 8.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Neur_chan_LBD PF02931.23 CDJ87213.1 - 2.9e-35 121.7 2.6 4.3e-35 121.1 2.6 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ87213.1 - 1.2e-26 94.3 0.4 2.7e-26 93.1 0.4 1.6 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Astacin PF01400.24 CDJ87214.1 - 2.3e-71 239.4 0.0 3.4e-71 238.8 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB PF00431.20 CDJ87214.1 - 3.2e-11 43.5 0.0 6.4e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 CUB domain TSP_1 PF00090.19 CDJ87214.1 - 5.4e-08 32.9 13.0 5.4e-08 32.9 13.0 3.1 2 0 0 2 2 2 1 Thrombospondin type 1 domain Peptidase_M10 PF00413.24 CDJ87214.1 - 0.002 18.0 0.0 0.68 9.8 0.0 2.4 2 0 0 2 2 2 2 Matrixin FAM101 PF15068.6 CDJ87214.1 - 0.027 14.4 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 FAM101 family Reprolysin_4 PF13583.6 CDJ87214.1 - 0.32 10.6 1.1 2.8 7.6 0.1 2.4 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF3810 PF12725.7 CDJ87214.1 - 0.36 10.1 1.2 0.92 8.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Ig_3 PF13927.6 CDJ87216.1 - 0.0002 21.9 0.2 0.69 10.6 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 CDJ87216.1 - 0.00027 21.2 0.8 0.93 9.9 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 CDJ87216.1 - 0.02 15.0 0.6 0.16 12.0 0.0 2.5 2 2 1 3 3 3 0 Immunoglobulin I-set domain V-set PF07686.17 CDJ87216.1 - 0.42 10.8 2.0 0.9 9.7 0.1 2.3 3 1 0 3 3 3 0 Immunoglobulin V-set domain DUF1456 PF07308.13 CDJ87217.1 - 0.037 14.4 2.0 0.22 11.9 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1456) LPP PF04728.13 CDJ87217.1 - 0.037 14.4 4.1 0.058 13.8 4.1 1.4 1 0 0 1 1 1 0 Lipoprotein leucine-zipper TIMELESS PF04821.14 CDJ87217.1 - 0.19 11.0 5.0 0.19 11.0 5.0 1.0 1 0 0 1 1 1 0 Timeless protein YabA PF06156.13 CDJ87217.1 - 0.96 10.1 5.4 0.98 10.1 5.4 1.0 1 0 0 1 1 1 0 Initiation control protein YabA AMPK1_CBM PF16561.5 CDJ87219.1 - 8.7e-28 96.4 0.6 1.4e-27 95.7 0.6 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 CDJ87219.1 - 1.6e-27 95.6 5.1 3.1e-27 94.6 5.1 1.5 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain Neur_chan_LBD PF02931.23 CDJ87221.1 - 1.1e-40 139.4 0.2 1.5e-40 139.0 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ87221.1 - 1.7e-16 61.0 5.3 3.5e-16 60.0 5.3 1.5 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CDJ87222.1 - 1.1e-40 139.4 0.2 1.5e-40 139.0 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ87222.1 - 1.7e-16 61.0 5.3 3.5e-16 60.0 5.3 1.5 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Sulfotransfer_1 PF00685.27 CDJ87223.1 - 8.9e-13 48.3 0.0 1.1e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CDJ87223.1 - 1.5e-10 41.8 0.0 2.6e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 CDJ87223.1 - 0.066 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase family Cadherin PF00028.17 CDJ87224.1 - 5e-07 30.1 0.0 0.00053 20.4 0.0 2.8 3 0 0 3 3 3 2 Cadherin domain CH PF00307.31 CDJ87225.1 - 3.3e-22 78.7 0.2 3.8e-22 78.5 0.2 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CDJ87225.1 - 0.093 12.6 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 CAMSAP CH domain PHD PF00628.29 CDJ87227.1 - 7.4e-05 22.6 7.8 0.00015 21.5 7.8 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CDJ87227.1 - 0.09 13.0 2.7 0.22 11.8 2.7 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD PF00628.29 CDJ87228.1 - 0.00014 21.6 8.5 0.00028 20.7 8.5 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CDJ87228.1 - 0.028 14.7 2.9 0.074 13.3 2.9 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain Peptidase_S9 PF00326.21 CDJ87230.1 - 5.3e-32 111.0 0.0 7.4e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CDJ87230.1 - 2.5e-08 33.9 0.7 3.3e-05 23.7 1.2 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ87230.1 - 4.2e-05 22.9 0.0 0.0028 17.0 0.0 2.2 1 1 1 2 2 2 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 CDJ87230.1 - 0.00035 20.6 0.0 0.00082 19.4 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 CDJ87230.1 - 0.00046 19.9 0.0 0.00074 19.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 CDJ87230.1 - 0.0023 18.6 7.6 0.042 14.4 6.2 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 CDJ87230.1 - 0.0043 16.6 0.0 0.016 14.8 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 CDJ87230.1 - 0.02 14.7 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold BTB PF00651.31 CDJ87231.1 - 4.7e-26 91.2 1.0 3.7e-25 88.3 0.4 2.6 1 1 1 2 2 2 1 BTB/POZ domain zf-C2H2 PF00096.26 CDJ87231.1 - 1.4e-15 56.7 62.7 0.0013 19.1 2.0 9.2 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ87231.1 - 2.9e-15 55.9 50.0 8e-06 26.1 0.5 10.4 10 0 0 10 10 10 5 Zinc-finger double domain zf-H2C2_5 PF13909.6 CDJ87231.1 - 9.2e-08 31.7 62.0 1.9e-06 27.5 1.5 8.3 8 0 0 8 8 8 3 C2H2-type zinc-finger domain BACK PF07707.15 CDJ87231.1 - 2.3e-07 30.9 0.1 9e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch zf-C2H2_4 PF13894.6 CDJ87231.1 - 4.6e-06 27.0 70.5 0.038 14.8 1.3 10.1 10 0 0 10 10 9 5 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CDJ87231.1 - 0.001 19.3 24.8 0.0042 17.3 3.2 4.8 1 1 4 5 5 5 2 C2H2-type zinc ribbon zf_C2H2_ZHX PF18387.1 CDJ87231.1 - 0.0022 17.6 37.2 0.21 11.2 0.1 7.5 5 3 3 8 8 8 3 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 CDJ87231.1 - 0.007 16.6 0.5 0.007 16.6 0.5 6.8 8 0 0 8 8 8 2 Zinc-finger double-stranded RNA-binding SAP130_C PF16014.5 CDJ87231.1 - 0.028 13.5 1.2 0.046 12.8 1.2 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus DUF3342 PF11822.8 CDJ87231.1 - 0.033 14.4 0.4 0.087 13.0 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) Exo70 PF03081.15 CDJ87231.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Exo70 exocyst complex subunit SpdB PF05122.13 CDJ87231.1 - 1.7 8.8 5.0 1.4 9.1 1.7 2.7 1 1 1 2 2 2 0 Mobile element transfer protein zinc_ribbon_15 PF17032.5 CDJ87231.1 - 2.5 8.9 27.4 0.8 10.5 2.2 5.1 3 1 2 5 5 5 0 zinc-ribbon family zf-C2HC_2 PF13913.6 CDJ87231.1 - 2.9 7.9 11.6 0.46 10.5 1.2 3.0 3 0 0 3 3 2 0 zinc-finger of a C2HC-type ADK_lid PF05191.14 CDJ87231.1 - 8.8 6.4 13.1 0.73 9.9 0.6 3.3 3 0 0 3 3 3 0 Adenylate kinase, active site lid MFS_1 PF07690.16 CDJ87232.1 - 0.088 11.7 9.3 0.014 14.3 5.4 1.5 2 0 0 2 2 2 0 Major Facilitator Superfamily TssN PF17555.2 CDJ87232.1 - 0.74 9.1 4.9 0.94 8.8 4.9 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN Hydrolase_4 PF12146.8 CDJ87235.1 - 6.8e-16 58.2 0.0 1.8e-12 47.0 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ87235.1 - 1.7e-14 54.1 0.0 3.9e-11 43.1 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ87235.1 - 1.4e-10 42.1 0.3 1.3e-09 39.0 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CDJ87235.1 - 8e-05 22.2 0.0 0.00016 21.2 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 CDJ87235.1 - 0.00013 21.9 0.0 0.0012 18.7 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.13 CDJ87235.1 - 0.00032 20.6 0.0 0.00052 19.9 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase DLH PF01738.18 CDJ87235.1 - 0.0017 17.9 0.0 0.0036 16.9 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family LIP PF03583.14 CDJ87235.1 - 0.0031 16.9 0.4 0.21 10.9 0.2 2.1 1 1 1 2 2 2 1 Secretory lipase Cutinase PF01083.22 CDJ87235.1 - 0.026 14.5 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 Cutinase DUF818 PF05677.12 CDJ87235.1 - 0.05 12.6 0.0 0.08 11.9 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) MOLO1 PF17175.4 CDJ87236.1 - 3.4e-22 78.8 0.0 6.6e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 CDJ87236.1 - 3.4e-07 30.5 0.0 3.2e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 TPM domain DUF2110 PF09883.9 CDJ87236.1 - 0.082 12.5 0.2 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2110) AphA_like PF14557.6 CDJ87236.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator STN1_2 PF09170.10 CDJ87237.1 - 0.0016 18.7 0.1 0.0022 18.3 0.1 1.2 1 0 0 1 1 1 1 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Orbi_VP6 PF01516.16 CDJ87237.1 - 0.0052 16.4 0.3 0.0061 16.1 0.3 1.1 1 0 0 1 1 1 1 Orbivirus helicase VP6 SLC12 PF03522.15 CDJ87239.1 - 4.4e-28 98.5 0.0 6.4e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Solute carrier family 12 AA_permease PF00324.21 CDJ87239.1 - 5.7e-24 84.6 47.0 7.4e-24 84.2 47.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CDJ87239.1 - 4e-08 32.5 52.3 5.8e-08 32.0 52.3 1.1 1 0 0 1 1 1 1 Amino acid permease TM2 PF05154.16 CDJ87240.1 - 1.3e-12 47.9 9.0 2.8e-12 46.8 9.0 1.5 1 0 0 1 1 1 1 TM2 domain zf-Tim10_DDP PF02953.15 CDJ87241.1 - 2.2e-20 72.0 3.5 2.2e-20 72.0 3.5 1.6 2 0 0 2 2 2 1 Tim10/DDP family zinc finger DUF5595 PF18077.1 CDJ87241.1 - 0.28 11.3 2.5 0.33 11.0 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Ig_3 PF13927.6 CDJ87242.1 - 1.4e-10 41.6 0.0 2.9e-08 34.2 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 CDJ87242.1 - 2.6e-10 40.3 0.0 2.8e-08 33.8 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 CDJ87242.1 - 4.7e-07 29.8 0.0 6.4e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.6 CDJ87242.1 - 4.5e-05 23.7 0.0 0.00022 21.5 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain fn3 PF00041.21 CDJ87242.1 - 0.00067 19.9 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Sushi PF00084.20 CDJ87242.1 - 0.0011 19.6 0.5 0.0047 17.5 0.1 2.3 3 0 0 3 3 3 1 Sushi repeat (SCR repeat) Pur_ac_phosph_N PF16656.5 CDJ87242.1 - 0.023 15.3 0.0 0.041 14.4 0.0 1.4 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain C2-set_2 PF08205.12 CDJ87242.1 - 0.041 13.9 0.0 1.3 9.1 0.0 2.7 2 1 0 2 2 2 0 CD80-like C2-set immunoglobulin domain V-set PF07686.17 CDJ87242.1 - 0.19 11.9 0.0 0.55 10.4 0.0 1.9 1 1 0 1 1 1 0 Immunoglobulin V-set domain RVT_1 PF00078.27 CDJ87243.1 - 4.7e-07 29.5 0.0 5e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PI3_PI4_kinase PF00454.27 CDJ87244.1 - 4.5e-29 102.0 0.0 5.9e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase HipA_C PF07804.12 CDJ87244.1 - 0.082 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 HipA-like C-terminal domain RVT_1 PF00078.27 CDJ87245.1 - 4.6e-32 111.3 0.0 9.3e-32 110.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDJ87245.1 - 3.2e-31 107.7 0.0 1.1e-30 106.0 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ87245.1 - 1.7e-28 98.6 0.0 5.1e-28 97.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ87245.1 - 1.7e-16 60.5 0.0 4.9e-16 59.0 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ87245.1 - 1.1e-14 54.3 0.7 2.7e-14 53.0 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain zf-CCHC PF00098.23 CDJ87245.1 - 0.00011 22.1 1.7 0.00011 22.1 1.7 2.3 2 0 0 2 2 2 1 Zinc knuckle gag-asp_proteas PF13975.6 CDJ87245.1 - 0.00036 21.0 0.0 0.0019 18.7 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease rve_3 PF13683.6 CDJ87245.1 - 0.0054 16.5 0.0 0.035 13.9 0.0 2.6 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_6 PF15288.6 CDJ87245.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ87245.1 - 0.15 12.1 6.3 0.23 11.4 1.5 3.0 3 0 0 3 3 3 0 Zinc knuckle UPF0242 PF06785.11 CDJ87246.1 - 0.0033 17.6 0.0 0.0045 17.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Pam17 PF08566.10 CDJ87246.1 - 0.015 15.2 0.1 0.02 14.8 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 HALZ PF02183.18 CDJ87246.1 - 0.061 13.5 1.0 0.1 12.9 1.0 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper NicO PF03824.16 CDJ87246.1 - 0.11 11.9 0.0 0.12 11.7 0.0 1.0 1 0 0 1 1 1 0 High-affinity nickel-transport protein Ntox8 PF15545.6 CDJ87246.1 - 0.15 12.2 2.5 0.8 9.8 0.1 2.5 1 1 2 3 3 3 0 Bacterial toxin 8 WD40 PF00400.32 CDJ87247.1 - 6.9e-05 23.5 0.8 0.86 10.6 0.4 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ87247.1 - 0.00021 21.5 0.0 0.082 13.2 0.0 3.0 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CDJ87247.1 - 0.11 13.0 0.0 2.5 8.7 0.0 2.8 2 0 0 2 2 2 0 PQQ-like domain Rrn6 PF10214.9 CDJ87247.1 - 0.97 7.8 8.1 2 6.8 8.1 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor ABC_tran_CTD PF16326.5 CDJ87248.1 - 0.019 15.2 2.0 0.019 15.2 2.0 2.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain zf-CCCH_7 PF18586.1 CDJ87248.1 - 0.27 11.6 2.8 8 6.9 0.3 3.1 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 LZ_Tnp_IS66 PF13007.7 CDJ87248.1 - 3.7 8.4 8.6 6.4 7.6 2.4 2.7 1 1 1 2 2 2 0 Transposase C of IS166 homeodomain Virulence_fact PF13769.6 CDJ87248.1 - 6.9 7.0 8.0 31 4.9 0.2 3.2 3 0 0 3 3 3 0 Virulence factor Ion_trans PF00520.31 CDJ87249.1 - 5e-253 834.8 87.2 2.3e-70 236.6 6.5 4.1 4 0 0 4 4 4 4 Ion transport protein Ca_chan_IQ PF08763.11 CDJ87249.1 - 9.7e-29 99.4 0.0 2e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain GPHH PF16905.5 CDJ87249.1 - 1.3e-28 98.5 0.1 8.5e-28 95.9 0.1 2.4 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 CDJ87249.1 - 2e-09 36.7 96.2 2.4e-06 26.5 9.1 10.3 7 4 3 10 10 10 8 Polycystin cation channel Waikav_capsid_1 PF12264.8 CDJ87249.1 - 0.08 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Waikavirus capsid protein 1 EF-hand_11 PF08976.11 CDJ87249.1 - 0.15 13.0 0.0 0.37 11.7 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain Pilin_N PF07790.11 CDJ87249.1 - 5.9 7.9 6.0 6.7 7.7 0.0 3.4 3 0 0 3 3 3 0 Archaeal Type IV pilin, N-terminal Pkinase PF00069.25 CDJ87250.1 - 1.7e-63 214.5 0.0 2.2e-63 214.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ87250.1 - 9.7e-38 129.9 0.0 1.2e-37 129.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CDJ87250.1 - 2.8e-09 37.5 2.1 7.4e-09 36.2 2.1 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CDJ87250.1 - 0.017 14.1 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 CDJ87250.1 - 0.023 14.0 0.0 0.034 13.5 0.0 1.5 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 CDJ87250.1 - 0.037 13.9 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 CDJ87250.1 - 0.066 12.8 0.0 13 5.3 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Exo_endo_phos_2 PF14529.6 CDJ87251.1 - 0.022 14.6 0.0 0.042 13.7 0.0 1.6 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Claudin_3 PF06653.11 CDJ87252.1 - 0.0015 18.5 9.6 0.004 17.1 9.6 1.7 1 1 0 1 1 1 1 Tight junction protein, Claudin-like DUF1218 PF06749.12 CDJ87252.1 - 0.047 14.2 3.9 0.43 11.1 2.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Claudin_2 PF13903.6 CDJ87252.1 - 0.35 10.6 5.9 0.48 10.2 5.9 1.3 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Orthoreo_P10 PF07204.11 CDJ87252.1 - 2 8.4 5.8 0.97 9.4 3.0 2.0 1 1 1 2 2 2 0 Orthoreovirus membrane fusion protein p10 DUF2207 PF09972.9 CDJ87252.1 - 2.2 7.0 6.0 0.23 10.2 1.2 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Exo_endo_phos PF03372.23 CDJ87253.1 - 5.7e-12 45.7 0.2 2.9e-11 43.3 0.2 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CDJ87253.1 - 0.0024 17.7 0.3 0.0077 16.1 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase TMEM71 PF15121.6 CDJ87254.1 - 0.16 11.6 0.0 0.17 11.5 0.0 1.0 1 0 0 1 1 1 0 TMEM71 protein family MRPL52 PF18699.1 CDJ87255.1 - 5.6e-28 97.0 0.2 6.2e-28 96.8 0.2 1.0 1 0 0 1 1 1 1 Mitoribosomal protein mL52 WD40 PF00400.32 CDJ87256.1 - 7.5e-37 124.7 12.1 7.3e-08 33.0 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ87256.1 - 2.8e-08 34.0 0.5 0.41 11.0 0.0 4.6 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L37ae PF01780.19 CDJ87257.1 - 2.5e-41 139.6 10.5 2.8e-41 139.5 10.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family DUF1451 PF07295.11 CDJ87257.1 - 0.006 16.6 1.0 0.0085 16.1 1.0 1.2 1 0 0 1 1 1 1 Zinc-ribbon containing domain Elf1 PF05129.13 CDJ87257.1 - 0.0065 16.5 0.2 0.0086 16.1 0.2 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Cytochrome_C7 PF14522.6 CDJ87257.1 - 0.0067 16.4 0.8 0.0087 16.0 0.8 1.2 1 0 0 1 1 1 1 Cytochrome c7 and related cytochrome c zf-H2C2_2 PF13465.6 CDJ87257.1 - 0.013 15.9 2.0 2.8 8.5 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.7 CDJ87257.1 - 0.014 15.4 2.3 0.021 14.8 2.3 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF1364 PF07102.12 CDJ87257.1 - 0.017 15.0 0.3 0.022 14.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) MRNIP PF15749.5 CDJ87257.1 - 0.027 15.2 2.4 2.5 8.8 0.5 2.4 1 1 2 3 3 3 0 MRN-interacting protein Rep_fac-A_C PF08646.10 CDJ87257.1 - 0.13 12.0 2.3 0.18 11.5 2.3 1.4 1 1 0 1 1 1 0 Replication factor-A C terminal domain zf-BED PF02892.15 CDJ87257.1 - 0.23 11.5 5.6 4.8 7.3 0.7 2.2 1 1 1 2 2 2 0 BED zinc finger CarbpepA_inh PF02977.15 CDJ87257.1 - 0.28 11.0 3.1 0.83 9.5 3.1 1.8 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor A2L_zn_ribbon PF08792.10 CDJ87257.1 - 0.43 10.4 3.2 3.9 7.3 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain GRASP55_65 PF04495.14 CDJ87258.1 - 8.3e-72 239.9 0.4 4.7e-52 176.0 0.1 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 CDJ87258.1 - 4.2e-08 33.4 0.1 0.00054 20.2 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CDJ87258.1 - 1.1e-06 28.4 0.0 0.05 13.5 0.0 2.6 2 0 0 2 2 2 2 PDZ domain SelP_N PF04592.14 CDJ87258.1 - 8.2 5.7 7.5 16 4.8 7.5 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region E1-E2_ATPase PF00122.20 CDJ87259.1 - 1.9e-51 174.1 0.1 1.9e-51 174.1 0.1 3.4 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CDJ87259.1 - 1.7e-37 128.9 8.9 2.6e-37 128.3 4.1 2.5 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CDJ87259.1 - 1.3e-20 74.6 2.2 4.8e-20 72.7 1.2 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDJ87259.1 - 1.1e-16 60.6 0.0 2.4e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CDJ87259.1 - 7.8e-16 57.5 0.0 2e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CDJ87259.1 - 0.0015 18.3 0.8 0.0075 16.0 0.6 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3784 PF12650.7 CDJ87259.1 - 0.66 10.2 3.2 2.5 8.3 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) FAM25 PF15825.5 CDJ87260.1 - 0.11 12.8 5.0 0.3 11.4 1.5 3.0 2 0 0 2 2 2 0 FAM25 family Phasin_2 PF09361.10 CDJ87260.1 - 0.6 10.4 4.0 1.4 9.2 4.0 1.6 1 0 0 1 1 1 0 Phasin protein 7TM_GPCR_Srw PF10324.9 CDJ87261.1 - 4.3e-35 121.5 11.8 5.8e-35 121.1 11.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 CDJ87261.1 - 4.7e-08 32.7 14.3 4.7e-08 32.7 14.3 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CDJ87261.1 - 0.0018 17.9 13.0 0.0018 17.9 13.0 2.3 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx GP41 PF00517.17 CDJ87261.1 - 0.85 9.5 3.0 0.9 9.4 0.2 2.2 2 0 0 2 2 2 0 Retroviral envelope protein DOMON PF03351.17 CDJ87262.1 - 2.2e-12 47.3 0.0 2.6e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 DOMON domain Adeno_E3_CR1 PF02440.15 CDJ87262.1 - 0.15 11.9 0.3 0.39 10.5 0.0 1.9 2 1 1 3 3 3 0 Adenovirus E3 region protein CR1 LRR_4 PF12799.7 CDJ87263.1 - 2e-05 24.8 0.6 2.2 8.8 0.0 3.9 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 CDJ87263.1 - 0.0034 17.2 1.5 0.0084 16.0 0.2 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CDJ87263.1 - 0.013 15.3 1.6 0.029 14.2 0.1 2.4 3 0 0 3 3 3 0 F-box domain LRR_8 PF13855.6 CDJ87263.1 - 0.019 14.7 3.0 3 7.7 0.7 3.1 2 0 0 2 2 2 0 Leucine rich repeat LRR_1 PF00560.33 CDJ87263.1 - 0.82 10.5 4.3 3.3 8.6 0.7 3.5 3 0 0 3 3 3 0 Leucine Rich Repeat GOLD_2 PF13897.6 CDJ87264.1 - 2.8e-70 235.2 0.4 2.8e-70 235.2 0.4 1.7 2 0 0 2 2 2 1 Golgi-dynamics membrane-trafficking DUF3245 PF11595.8 CDJ87264.1 - 0.018 15.6 1.6 0.018 15.6 1.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Ribosomal_60s PF00428.19 CDJ87264.1 - 2.1 9.0 7.2 1.8 9.2 2.1 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein PID PF00640.23 CDJ87265.1 - 1.7e-25 89.7 0.6 1.9e-25 89.5 0.6 1.0 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 CDJ87265.1 - 1.1e-10 41.8 0.4 1.6e-10 41.2 0.4 1.2 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.6 CDJ87265.1 - 0.00012 22.1 0.0 0.00012 22.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SIN1_PH PF16979.5 CDJ87265.1 - 0.055 13.7 1.0 0.12 12.7 1.0 1.6 1 1 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology Lin0512_fam PF09585.10 CDJ87265.1 - 0.078 13.0 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein (Lin0512_fam) Peptidase_M16 PF00675.20 CDJ87267.1 - 2e-44 151.1 4.2 4e-44 150.2 0.4 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CDJ87267.1 - 1.4e-24 87.2 0.0 3.8e-20 72.7 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain Pox_EPC_I2-L1 PF12575.8 CDJ87267.1 - 0.023 14.9 0.1 3.6 7.9 0.0 2.8 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 Dpoe2NT PF12213.8 CDJ87267.1 - 0.11 12.8 0.1 0.3 11.4 0.1 1.7 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal HA2 PF04408.23 CDJ87268.1 - 1.4e-24 86.5 0.2 1.4e-24 86.5 0.2 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDJ87268.1 - 2.5e-21 75.8 0.0 6.5e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDJ87268.1 - 2.9e-12 46.9 0.0 6.7e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ87268.1 - 1.2e-05 25.1 0.1 3.8e-05 23.5 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CDJ87268.1 - 2.6e-05 24.6 0.1 5.2e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDJ87268.1 - 0.00044 20.5 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ87268.1 - 0.005 16.6 0.0 0.0086 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CDJ87268.1 - 0.0074 15.9 0.1 0.014 15.0 0.1 1.5 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.15 CDJ87268.1 - 0.023 14.7 0.0 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 CDJ87268.1 - 0.04 13.4 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 CDJ87268.1 - 0.088 12.2 0.0 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 CDJ87268.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RSB_motif PF16294.5 CDJ87268.1 - 5.9 7.2 15.0 12 6.2 15.0 1.5 1 0 0 1 1 1 0 RNSP1-SAP18 binding (RSB) motif DUF1645 PF07816.11 CDJ87268.1 - 6.9 7.2 18.2 3.4 8.2 14.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) BTB_2 PF02214.22 CDJ87269.1 - 5e-20 71.7 0.0 1.3e-19 70.3 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 CDJ87269.1 - 0.0018 18.5 0.0 0.011 16.0 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 CDJ87269.1 - 0.02 15.0 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Mur_ligase_C PF02875.21 CDJ87269.1 - 0.08 13.2 0.0 23 5.3 0.0 2.8 3 0 0 3 3 3 0 Mur ligase family, glutamate ligase domain Brix PF04427.18 CDJ87270.1 - 9.1e-34 117.2 1.9 1.4e-33 116.6 1.9 1.3 1 0 0 1 1 1 1 Brix domain GCN5L1 PF06320.13 CDJ87270.1 - 0.027 14.6 0.9 0.087 13.0 0.9 1.8 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Snf7 PF03357.21 CDJ87270.1 - 0.075 12.6 7.9 1.3 8.5 1.2 3.3 2 1 1 3 3 3 0 Snf7 DnaJ PF00226.31 CDJ87271.1 - 1.9e-28 98.4 2.4 1.9e-28 98.4 2.4 2.4 2 1 0 2 2 2 1 DnaJ domain CdvA PF18822.1 CDJ87271.1 - 0.00086 19.1 4.9 0.0017 18.1 4.9 1.6 1 0 0 1 1 1 1 CdvA-like coiled-coil domain She9_MDM33 PF05546.11 CDJ87271.1 - 0.028 14.2 0.9 0.049 13.4 0.9 1.3 1 0 0 1 1 1 0 She9 / Mdm33 family eIF3_N PF09440.10 CDJ87271.1 - 0.042 14.3 1.8 0.08 13.4 1.8 1.4 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain COG2 PF06148.11 CDJ87271.1 - 0.058 13.5 1.6 0.11 12.6 1.6 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PP31 PF05311.11 CDJ87271.1 - 0.11 12.0 6.3 0.17 11.4 5.4 1.7 1 1 1 2 2 2 0 Baculovirus 33KDa late protein (PP31) IMS_HHH PF11798.8 CDJ87271.1 - 0.14 12.5 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif H-kinase_dim PF02895.14 CDJ87271.1 - 0.26 11.7 1.2 0.57 10.6 1.2 1.5 1 0 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain Filament PF00038.21 CDJ87271.1 - 0.42 10.2 10.4 0.16 11.5 4.4 2.1 2 0 0 2 2 2 0 Intermediate filament protein KELK PF15796.5 CDJ87271.1 - 0.74 10.3 12.9 0.098 13.1 8.4 1.9 2 0 0 2 2 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Atg14 PF10186.9 CDJ87271.1 - 2.2 7.3 5.6 4 6.4 5.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GrpE PF01025.19 CDJ87271.1 - 2.2 7.9 9.3 4.4 6.9 9.3 1.4 1 0 0 1 1 1 0 GrpE DUF2681 PF10883.8 CDJ87271.1 - 3.4 8.1 6.4 2.4 8.6 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF4337 PF14235.6 CDJ87271.1 - 3.5 7.7 13.5 0.6 10.2 8.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) ZapB PF06005.12 CDJ87271.1 - 9 6.8 9.9 42 4.7 0.0 2.5 2 0 0 2 2 2 0 Cell division protein ZapB eIF2A PF08662.11 CDJ87272.1 - 4e-71 238.9 0.0 1.1e-70 237.5 0.1 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Asp PF00026.23 CDJ87273.1 - 1.5e-15 57.4 0.0 2.4e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ87273.1 - 3.3e-07 30.7 0.1 4.7e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal DUF4252 PF14060.6 CDJ87273.1 - 0.14 12.0 0.4 0.29 11.0 0.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4252) MFS_1 PF07690.16 CDJ87275.1 - 2.5e-08 33.3 27.2 1.1e-07 31.1 18.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FTR PF01913.18 CDJ87277.1 - 0.033 14.1 0.1 0.073 13.0 0.1 1.5 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase Glyco_transf_41 PF13844.6 CDJ87278.1 - 7.7e-256 848.9 0.1 1.1e-255 848.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 41 TPR_1 PF00515.28 CDJ87278.1 - 2.1e-82 267.8 39.5 3.1e-08 33.1 0.0 13.7 14 0 0 14 14 14 11 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ87278.1 - 1.3e-77 255.2 43.3 1.1e-11 44.2 0.5 12.7 3 2 10 13 13 13 12 TPR repeat TPR_2 PF07719.17 CDJ87278.1 - 3.5e-63 204.7 34.0 1.8e-06 27.6 0.1 13.5 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ87278.1 - 5.4e-58 188.4 26.9 1e-05 25.3 0.0 13.0 13 0 0 13 13 12 12 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ87278.1 - 9.9e-53 172.8 42.4 2.4e-06 27.5 0.3 13.5 15 0 0 15 15 13 12 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ87278.1 - 3.6e-37 126.7 16.5 4.2e-08 33.7 0.2 8.0 6 1 2 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ87278.1 - 2.4e-36 123.9 38.2 8e-11 42.1 3.1 9.5 5 3 5 10 10 9 7 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ87278.1 - 4.5e-33 113.6 34.2 1.2e-06 28.9 0.1 8.2 4 2 3 8 8 8 8 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ87278.1 - 4.9e-31 104.8 19.1 0.03 15.1 0.1 12.3 5 3 7 12 12 12 6 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ87278.1 - 7.3e-29 97.7 17.7 0.0032 17.4 0.0 12.3 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ87278.1 - 1.6e-26 91.4 50.4 4.2e-06 26.4 0.4 12.3 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ87278.1 - 1e-12 48.0 10.3 0.0078 16.3 0.3 6.6 5 1 2 7 7 7 4 Tetratricopeptide repeat NARP1 PF12569.8 CDJ87278.1 - 3.6e-10 39.4 6.9 0.017 14.1 0.0 5.1 2 1 1 5 5 5 3 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 CDJ87278.1 - 2.6e-09 37.1 20.9 0.35 11.6 0.0 9.6 11 0 0 11 11 8 2 Tetratricopeptide repeat TPR_4 PF07721.14 CDJ87278.1 - 6.3e-09 35.6 7.6 0.3 11.8 1.0 8.5 9 0 0 9 9 8 1 Tetratricopeptide repeat FAT PF02259.23 CDJ87278.1 - 1.9e-06 27.4 2.7 0.19 10.9 0.4 5.9 2 2 3 5 5 5 2 FAT domain TPR_15 PF13429.6 CDJ87278.1 - 0.00012 21.4 10.9 0.35 10.0 0.9 3.8 1 1 0 3 3 3 3 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 CDJ87278.1 - 0.00017 21.2 11.6 0.015 14.8 0.1 3.7 4 0 0 4 4 4 2 Est1 DNA/RNA binding domain TPR_3 PF07720.12 CDJ87278.1 - 0.0024 17.8 11.2 0.91 9.6 0.0 6.2 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CDJ87278.1 - 0.0033 16.8 29.6 0.0067 15.8 0.3 5.3 2 1 4 6 6 6 3 MalT-like TPR region BTAD PF03704.17 CDJ87278.1 - 0.0087 16.5 7.1 0.62 10.5 0.2 4.2 3 1 0 3 3 3 1 Bacterial transcriptional activator domain Rab_eff_C PF04698.12 CDJ87278.1 - 0.074 11.3 0.0 0.14 10.4 0.0 1.3 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus SHNi-TPR PF10516.9 CDJ87278.1 - 0.093 12.2 4.5 35 3.9 0.0 5.6 6 1 1 7 7 7 0 SHNi-TPR TOM20_plant PF06552.12 CDJ87278.1 - 0.1 12.3 0.5 6.8 6.4 0.1 3.3 2 2 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 DUF357 PF04010.13 CDJ87278.1 - 0.13 12.3 3.1 2.8 8.1 0.1 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF357) TPR_20 PF14561.6 CDJ87278.1 - 0.21 11.9 15.3 16 5.9 0.0 6.3 5 1 2 7 7 7 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CDJ87278.1 - 0.27 11.2 13.2 60 3.6 0.2 6.4 5 1 1 6 6 6 0 Mad3/BUB1 homology region 1 TPR_21 PF09976.9 CDJ87278.1 - 0.59 9.8 22.5 2.2 8.0 1.8 5.4 3 2 2 5 5 5 0 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 CDJ87278.1 - 4.2 7.7 25.1 0.94 9.7 2.1 4.8 4 1 0 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Sec16_C PF12931.7 CDJ87278.1 - 5.7 6.5 7.7 2.6 7.6 0.0 3.6 3 1 1 4 4 4 0 Sec23-binding domain of Sec16 dNK PF01712.19 CDJ87279.1 - 2.1e-42 145.3 1.2 2.9e-42 144.8 1.2 1.1 1 0 0 1 1 1 1 Deoxynucleoside kinase Thymidylate_kin PF02223.17 CDJ87279.1 - 0.056 13.1 0.1 0.21 11.3 0.0 1.9 1 1 1 2 2 2 0 Thymidylate kinase Keratin_2_head PF16208.5 CDJ87280.1 - 0.012 15.7 16.6 0.014 15.6 16.6 1.1 1 0 0 1 1 1 0 Keratin type II head Lamprin PF06403.11 CDJ87280.1 - 0.059 13.3 10.3 0.059 13.3 9.3 1.4 1 1 1 2 2 2 0 Lamprin Ctr PF04145.15 CDJ87281.1 - 2.4e-39 135.3 0.6 3.5e-39 134.8 0.6 1.2 1 0 0 1 1 1 1 Ctr copper transporter family Pkinase PF00069.25 CDJ87282.1 - 4.3e-48 164.0 0.1 4.3e-48 164.0 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ87282.1 - 5.5e-20 71.7 0.0 9.9e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ87282.1 - 0.004 16.5 0.0 0.0097 15.3 0.0 1.6 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CDJ87282.1 - 0.0057 16.3 0.1 0.0057 16.3 0.1 3.6 4 1 0 4 4 4 1 RIO1 family Pox_ser-thr_kin PF05445.11 CDJ87282.1 - 0.044 12.8 0.0 0.084 11.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-CHCC PF10276.9 CDJ87283.1 - 3e-18 65.6 2.6 3e-18 65.6 2.6 1.6 2 0 0 2 2 2 1 Zinc-finger domain Asp PF00026.23 CDJ87285.1 - 3.5e-89 299.3 1.1 4.3e-89 299.1 1.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ87285.1 - 8.6e-11 42.4 10.7 1.1e-10 42.1 6.6 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ87285.1 - 8.6e-06 25.6 0.0 0.00014 21.7 0.0 2.7 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CDJ87285.1 - 0.0021 18.7 0.1 0.9 10.2 0.0 3.0 3 0 0 3 3 3 1 Aspartyl protease DENN PF02141.21 CDJ87286.1 - 2.9e-54 183.9 0.2 5.9e-54 182.8 0.2 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 CDJ87286.1 - 2.4e-09 37.0 5.1 2.4e-09 37.0 5.1 2.1 2 0 0 2 2 2 1 dDENN domain uDENN PF03456.18 CDJ87286.1 - 1.9e-05 25.3 0.8 0.00051 20.7 0.5 3.1 2 1 1 3 3 3 1 uDENN domain PPR_2 PF13041.6 CDJ87286.1 - 3.7e-05 23.8 0.0 0.00023 21.3 0.0 2.2 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.20 CDJ87286.1 - 0.032 14.5 0.0 0.087 13.1 0.0 1.8 1 0 0 1 1 1 0 PPR repeat PPR_3 PF13812.6 CDJ87286.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 1 0 1 1 1 0 Pentatricopeptide repeat domain MARVEL PF01284.23 CDJ87287.1 - 6.6e-11 42.4 28.0 8.4e-11 42.1 28.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain B3 PF02362.21 CDJ87287.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 B3 DNA binding domain DUF3724 PF12521.8 CDJ87287.1 - 0.15 12.0 2.2 10 6.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3724) MRP-S23 PF10484.9 CDJ87288.1 - 2e-38 131.5 0.3 3.1e-38 130.9 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S23 MRP-S25 PF13741.6 CDJ87288.1 - 0.0039 16.8 0.8 0.56 9.7 0.0 2.3 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 tRNA-synt_2c PF01411.19 CDJ87289.1 - 2.5e-221 736.0 0.0 1.1e-220 733.9 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class II (A) DHHA1 PF02272.19 CDJ87289.1 - 4.1e-18 66.1 5.8 4.1e-18 66.1 5.8 2.6 4 0 0 4 4 4 1 DHHA1 domain tRNA_SAD PF07973.14 CDJ87289.1 - 1.1e-15 57.4 0.7 2.3e-15 56.4 0.7 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain PTSIIA_gutA PF03829.13 CDJ87289.1 - 0.085 12.7 0.1 1.8 8.5 0.0 2.8 2 1 1 3 3 3 0 PTS system glucitol/sorbitol-specific IIA component PDZ_6 PF17820.1 CDJ87290.1 - 0.027 14.3 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 PDZ domain DUF4704 PF15787.5 CDJ87291.1 - 3.7e-76 256.0 7.0 4.7e-76 255.7 1.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 CDJ87291.1 - 1.5e-12 47.9 0.0 2.9e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily AbiJ_NTD5 PF18865.1 CDJ87291.1 - 0.049 13.4 0.1 0.95 9.3 0.0 2.4 2 0 0 2 2 2 0 AbiJ N-terminal domain 5 G-alpha PF00503.20 CDJ87292.1 - 3.5e-113 378.4 12.5 4.5e-113 378.0 12.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDJ87292.1 - 1.5e-15 57.1 4.6 5.6e-12 45.5 1.4 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 CDJ87292.1 - 3.4e-05 24.1 1.7 0.22 11.7 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 CDJ87292.1 - 0.0026 17.2 0.0 0.0051 16.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein Ras PF00071.22 CDJ87292.1 - 0.0035 17.0 1.4 1.6 8.3 0.0 2.7 2 1 0 2 2 2 2 Ras family Gtr1_RagA PF04670.12 CDJ87292.1 - 0.0076 15.6 9.7 0.02 14.3 3.7 3.0 2 2 0 2 2 2 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 CDJ87292.1 - 0.024 15.1 0.1 0.18 12.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Bac_DnaA PF00308.18 CDJ87292.1 - 0.028 14.2 0.5 0.045 13.6 0.1 1.6 2 0 0 2 2 2 0 Bacterial dnaA protein NADH5_C PF06455.11 CDJ87292.1 - 0.062 12.9 0.1 0.062 12.9 0.1 1.7 2 0 0 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus AAA_14 PF13173.6 CDJ87292.1 - 0.093 12.8 0.6 0.7 9.9 0.6 2.5 1 1 0 1 1 1 0 AAA domain Pkinase_Tyr PF07714.17 CDJ87293.1 - 2e-80 269.8 0.0 6.1e-80 268.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ87293.1 - 7.3e-32 110.8 0.0 1.5e-31 109.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 CDJ87293.1 - 4.6e-18 65.3 11.7 0.00091 19.5 0.1 7.5 6 1 0 6 6 6 4 Fibronectin type III domain Tissue_fac PF01108.17 CDJ87293.1 - 0.019 14.8 0.3 3.8 7.4 0.1 3.3 2 0 0 2 2 2 0 Tissue factor DNA_pol_E_B PF04042.16 CDJ87293.1 - 0.09 12.1 0.1 0.2 11.0 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B 7tm_1 PF00001.21 CDJ87295.1 - 7.2e-14 51.7 18.4 1e-13 51.2 18.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CopD PF05425.13 CDJ87295.1 - 0.65 10.4 7.1 0.18 12.2 0.9 2.9 3 0 0 3 3 3 0 Copper resistance protein D DUF1248 PF06852.12 CDJ87297.1 - 1.3e-11 44.3 2.6 1.7e-11 43.9 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1248) Acetyltransf_1 PF00583.25 CDJ87297.1 - 2.5e-08 34.1 0.0 2.5e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_18 PF18014.1 CDJ87297.1 - 5.1e-05 23.1 0.0 8.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDJ87297.1 - 0.00042 20.2 0.0 0.0048 16.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDJ87297.1 - 0.00054 20.3 0.0 0.01 16.2 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDJ87297.1 - 0.012 15.5 0.0 5.1 7.1 0.0 2.4 2 0 0 2 2 2 0 FR47-like protein COMMD1_N PF17221.3 CDJ87298.1 - 0.035 14.4 0.6 9.6 6.6 0.0 2.5 2 0 0 2 2 2 0 COMMD1 N-terminal domain RF-1 PF00472.20 CDJ87298.1 - 0.11 12.5 3.9 0.77 9.7 3.8 2.4 1 1 0 1 1 1 0 RF-1 domain Sds3 PF08598.11 CDJ87298.1 - 3.1 7.8 10.1 4.8 7.1 9.3 1.4 1 1 0 1 1 1 0 Sds3-like Mak10 PF04112.13 CDJ87299.1 - 2e-16 59.9 0.4 3e-14 52.9 0.4 2.6 1 1 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Ribosomal_S2 PF00318.20 CDJ87300.1 - 7.8e-41 139.7 1.6 1.8e-22 79.6 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 DUF3996 PF13161.6 CDJ87300.1 - 0.027 14.2 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3996) Acid_phosphat_B PF03767.14 CDJ87300.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) I-set PF07679.16 CDJ87301.1 - 1.2e-34 118.2 0.0 9.3e-12 44.9 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ87301.1 - 1.2e-22 80.3 0.0 7.6e-09 36.1 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 CDJ87301.1 - 4.6e-18 65.2 0.0 3.2e-05 24.0 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 CDJ87301.1 - 2.2e-12 47.1 0.0 0.00025 21.2 0.0 4.1 3 1 0 3 3 3 2 Immunoglobulin V-set domain Ig_2 PF13895.6 CDJ87301.1 - 4.9e-12 46.0 0.0 3.5e-05 24.1 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_6 PF18452.1 CDJ87301.1 - 1.9e-08 33.7 0.0 0.0091 15.5 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Izumo-Ig PF16706.5 CDJ87301.1 - 2.7e-05 24.1 0.0 0.14 12.2 0.0 3.4 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 CDJ87301.1 - 0.00031 21.0 0.1 1.5 9.2 0.0 4.1 3 2 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.8 CDJ87301.1 - 0.00046 20.4 0.0 0.082 13.1 0.0 2.7 3 0 0 3 3 3 1 Natural killer cell receptor 2B4 Ig_5 PF16681.5 CDJ87301.1 - 0.032 14.6 0.3 51 4.4 0.0 4.0 3 2 0 3 3 3 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pkinase PF00069.25 CDJ87302.1 - 3.1e-49 167.7 0.0 4.8e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ribosomal_L4 PF00573.22 CDJ87302.1 - 5.1e-39 133.9 0.0 8.8e-39 133.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Pkinase_Tyr PF07714.17 CDJ87302.1 - 3.7e-26 92.0 0.0 7e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PHD PF00628.29 CDJ87302.1 - 1.4e-08 34.4 8.0 3.4e-08 33.2 8.0 1.7 1 0 0 1 1 1 1 PHD-finger Kinase-like PF14531.6 CDJ87302.1 - 3.5e-07 29.8 0.0 0.00011 21.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CDJ87302.1 - 0.00028 20.3 0.0 0.00065 19.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family C1_1 PF00130.22 CDJ87302.1 - 0.0005 19.9 6.9 0.00061 19.6 4.7 2.2 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 CDJ87302.1 - 0.0014 18.3 4.5 0.0033 17.1 4.5 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 CDJ87302.1 - 0.0017 17.8 2.2 0.0049 16.4 2.2 1.8 1 0 0 1 1 1 1 PHD-finger RIO1 PF01163.22 CDJ87302.1 - 0.0066 16.1 0.1 0.014 15.0 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 CDJ87302.1 - 0.0086 14.9 0.0 0.022 13.5 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase C1_2 PF03107.16 CDJ87302.1 - 0.087 13.2 5.9 0.042 14.2 1.3 2.6 3 0 0 3 3 3 0 C1 domain APH PF01636.23 CDJ87302.1 - 0.12 12.3 0.0 0.71 9.7 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family FYVE_2 PF02318.16 CDJ87302.1 - 0.14 12.4 4.1 0.41 10.9 4.1 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RRPl_C4 PF17026.5 CDJ87302.1 - 0.26 11.4 3.8 0.6 10.2 3.8 1.6 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Prok-RING_1 PF14446.6 CDJ87302.1 - 8.9 6.3 13.9 0.24 11.4 6.1 2.4 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 FARP PF01581.16 CDJ87303.1 - 1.6e-06 27.6 24.6 3.1 8.7 0.7 5.6 5 0 0 5 5 5 5 FMRFamide related peptide family Prolactin_RP PF15172.6 CDJ87303.1 - 0.0006 19.4 0.9 14 5.4 0.0 4.1 3 1 1 4 4 4 3 Prolactin-releasing peptide hNIFK_binding PF12196.8 CDJ87303.1 - 0.059 12.9 10.3 16 5.1 0.0 5.0 3 1 2 5 5 5 0 FHA Ki67 binding domain of hNIFK PsbN PF02468.15 CDJ87303.1 - 0.07 13.0 0.5 30 4.6 0.0 3.7 4 0 0 4 4 4 0 Photosystem II reaction centre N protein (psbN) LZ_Tnp_IS66 PF13007.7 CDJ87303.1 - 0.9 10.4 7.4 8.6 7.2 4.5 3.2 1 1 1 2 2 2 0 Transposase C of IS166 homeodomain VWA PF00092.28 CDJ87304.1 - 0.0041 17.4 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain SK_channel PF03530.14 CDJ87305.1 - 8.4e-37 125.7 1.3 8.4e-37 125.7 1.3 2.5 3 1 0 3 3 3 1 Calcium-activated SK potassium channel CaMBD PF02888.16 CDJ87305.1 - 4.7e-30 103.6 4.9 9.4e-30 102.6 4.9 1.5 1 0 0 1 1 1 1 Calmodulin binding domain Ion_trans_2 PF07885.16 CDJ87305.1 - 1.1e-15 57.3 1.1 1.1e-15 57.3 1.1 2.4 3 0 0 3 3 3 1 Ion channel Prefoldin_2 PF01920.20 CDJ87305.1 - 0.016 15.1 0.1 0.039 13.9 0.1 1.7 1 1 0 1 1 1 0 Prefoldin subunit Ntox28 PF15605.6 CDJ87305.1 - 0.02 15.1 0.6 0.045 14.0 0.1 1.8 2 0 0 2 2 2 0 Bacterial toxin 28 Lig_chan PF00060.26 CDJ87305.1 - 0.099 12.5 0.7 0.22 11.3 0.1 2.0 2 0 0 2 2 2 0 Ligand-gated ion channel Osmo_CC PF08946.10 CDJ87305.1 - 0.14 12.4 0.1 0.52 10.6 0.1 1.9 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Homeodomain PF00046.29 CDJ87307.1 - 2.4e-22 78.5 6.2 2.4e-22 78.5 6.2 1.5 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CDJ87307.1 - 0.0093 15.9 0.7 0.02 14.8 0.2 1.9 2 0 0 2 2 2 1 Homeobox KN domain CENP-B_N PF04218.13 CDJ87307.1 - 0.047 13.3 0.2 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain YdaS_antitoxin PF15943.5 CDJ87307.1 - 0.075 12.9 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Homez PF11569.8 CDJ87307.1 - 0.11 12.0 0.2 0.22 11.0 0.2 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DFRP_C PF16543.5 CDJ87307.1 - 0.34 11.4 9.4 0.66 10.5 0.4 2.2 1 1 1 2 2 2 0 DRG Family Regulatory Proteins, Tma46 BTB PF00651.31 CDJ87308.1 - 0.034 14.4 0.1 0.16 12.2 0.1 2.0 2 0 0 2 2 2 0 BTB/POZ domain DUF3614 PF12267.8 CDJ87308.1 - 1.7 9.2 6.1 11 6.4 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3614) LRR_4 PF12799.7 CDJ87309.1 - 6.8e-10 39.0 10.4 0.024 15.1 1.1 4.5 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_2 PF07723.13 CDJ87309.1 - 4.1e-06 27.2 4.3 0.016 15.8 0.7 2.9 2 0 0 2 2 2 2 Leucine Rich Repeat LRR_6 PF13516.6 CDJ87309.1 - 7e-06 25.7 15.2 0.049 13.7 0.2 6.5 7 0 0 7 7 7 3 Leucine Rich repeat LRR_8 PF13855.6 CDJ87309.1 - 1.5e-05 24.7 10.2 0.16 11.7 1.3 4.6 4 2 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 CDJ87309.1 - 6.4e-05 23.0 6.5 1.5 9.7 0.9 5.0 4 1 0 4 4 4 2 Leucine Rich Repeat PDGF PF00341.17 CDJ87310.1 - 4.5e-08 33.3 9.6 4.5e-08 33.3 9.6 2.8 3 1 0 3 3 3 1 PDGF/VEGF domain CXCXC PF03128.14 CDJ87310.1 - 0.019 15.3 6.1 0.019 15.3 6.1 5.6 6 0 0 6 6 6 0 CXCXC repeat Clathrin PF00637.20 CDJ87311.1 - 2.8e-198 649.7 36.6 2.6e-32 111.7 4.6 7.9 8 1 1 9 9 9 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 CDJ87311.1 - 9.4e-38 126.7 1.4 3.8e-06 26.9 0.0 6.5 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 CDJ87311.1 - 2.9e-29 100.8 1.3 1.9e-28 98.2 0.1 3.2 3 0 0 3 3 3 1 Clathrin-H-link Clathrin-link PF09268.10 CDJ87311.1 - 1.7e-12 46.4 0.2 4.8e-12 45.0 0.2 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 CDJ87311.1 - 3.2e-07 29.8 5.3 0.03 13.4 0.2 4.1 4 0 0 4 4 4 2 Coatomer WD associated region TPR_14 PF13428.6 CDJ87311.1 - 0.00012 22.6 4.7 84 4.4 0.2 8.5 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ87311.1 - 0.00014 21.7 2.9 52 4.3 0.0 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ87311.1 - 0.002 17.8 0.0 53 3.9 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ87311.1 - 0.0068 16.4 10.3 0.34 11.0 0.1 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ87311.1 - 0.016 15.7 5.7 32 5.1 0.1 6.4 5 1 1 6 6 6 0 Tetratricopeptide repeat ABC_tran PF00005.27 CDJ87312.1 - 6.8e-52 175.6 0.0 8.3e-29 100.8 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CDJ87312.1 - 2.2e-51 175.0 35.6 1.8e-35 122.7 18.6 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 CDJ87312.1 - 1.9e-20 73.9 2.9 1.5e-06 28.3 0.0 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CDJ87312.1 - 9.3e-06 26.3 4.5 0.052 14.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.19 CDJ87312.1 - 2.1e-05 24.1 0.0 1.7 8.0 0.0 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CDJ87312.1 - 0.00045 19.9 2.9 0.2 11.4 0.1 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain DUF4162 PF13732.6 CDJ87312.1 - 0.00091 19.9 0.1 0.0049 17.5 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) MMR_HSR1 PF01926.23 CDJ87312.1 - 0.01 15.9 0.0 8.2 6.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 CDJ87312.1 - 0.023 14.0 0.1 7.4 5.8 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_13 PF13166.6 CDJ87312.1 - 0.035 12.8 0.3 0.57 8.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 CDJ87312.1 - 0.056 13.2 0.6 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal RsgA_GTPase PF03193.16 CDJ87312.1 - 0.063 13.2 3.5 0.53 10.2 0.1 3.2 4 0 0 4 4 4 0 RsgA GTPase SbcCD_C PF13558.6 CDJ87312.1 - 0.069 13.4 0.0 15 5.9 0.0 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 CDJ87312.1 - 0.092 12.4 0.1 13 5.3 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain CbiA PF01656.23 CDJ87312.1 - 0.13 12.4 0.0 0.38 10.8 0.0 1.9 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_27 PF13514.6 CDJ87312.1 - 0.17 11.4 0.2 8.8 5.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CDJ87312.1 - 0.18 11.5 0.9 6.8 6.4 0.4 2.8 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 CDJ87312.1 - 0.2 11.3 3.0 4.9 6.7 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SWIB PF02201.18 CDJ87314.1 - 1.7e-22 79.1 0.0 3.6e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 CDJ87314.1 - 0.0015 18.4 0.9 0.0034 17.3 0.9 1.7 1 0 0 1 1 1 1 DEK C terminal domain Ndc1_Nup PF09531.10 CDJ87314.1 - 0.24 10.0 1.4 0.31 9.7 1.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup V_ATPase_I PF01496.19 CDJ87314.1 - 4.5 5.1 4.6 6.4 4.5 4.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SRP-alpha_N PF04086.13 CDJ87314.1 - 6.6 6.6 26.6 0.27 11.1 19.8 1.8 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal RPAP2_Rtr1 PF04181.13 CDJ87315.1 - 1.1e-13 51.2 0.5 2.3e-13 50.3 0.5 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family Tubulin PF00091.25 CDJ87316.1 - 7.4e-69 231.9 0.0 1e-68 231.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDJ87316.1 - 3.7e-50 169.3 0.0 5.6e-50 168.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CDJ87316.1 - 0.0048 16.6 0.0 0.0088 15.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain MSP PF01716.18 CDJ87316.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide TUDOR PF00567.24 CDJ87317.1 - 1.8e-22 79.7 0.0 2.9e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Tudor domain KH_1 PF00013.29 CDJ87317.1 - 6.3e-11 41.9 0.3 1e-10 41.3 0.3 1.3 1 0 0 1 1 1 1 KH domain MFS_1 PF07690.16 CDJ87319.1 - 6.9e-31 107.4 34.5 6.9e-31 107.4 34.5 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ87319.1 - 4.4e-06 25.8 12.0 4.4e-06 25.8 12.0 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 CDJ87319.1 - 3.1e-05 22.7 8.4 3.1e-05 22.7 8.4 3.6 2 1 0 2 2 2 1 MFS/sugar transport protein OATP PF03137.20 CDJ87319.1 - 0.00069 18.0 24.9 0.076 11.3 0.7 4.3 1 1 3 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family EMP70 PF02990.16 CDJ87319.1 - 4.9 5.7 16.5 0.078 11.6 3.0 2.9 1 1 2 3 3 3 0 Endomembrane protein 70 Diphthamide_syn PF01866.17 CDJ87320.1 - 8.1e-121 403.1 0.1 9.7e-121 402.9 0.1 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DUF4899 PF16240.5 CDJ87320.1 - 0.1 11.7 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4899) CH PF00307.31 CDJ87321.1 - 1.7e-23 82.8 0.0 2e-23 82.7 0.0 1.0 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CDJ87321.1 - 2.6e-08 33.6 0.0 3.6e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 CAMSAP CH domain CH_2 PF06294.11 CDJ87321.1 - 0.004 17.3 0.0 0.0051 16.9 0.0 1.2 1 0 0 1 1 1 1 CH-like domain in sperm protein Filamin PF00630.19 CDJ87322.1 - 2e-11 44.6 0.1 6e-11 43.1 0.0 1.9 2 0 0 2 2 1 1 Filamin/ABP280 repeat zf-RING_5 PF14634.6 CDJ87322.1 - 8.3e-07 28.9 5.1 8.3e-07 28.9 5.1 2.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CDJ87322.1 - 2.2e-05 24.7 6.3 2.2e-05 24.7 6.3 3.0 3 0 0 3 3 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CDJ87322.1 - 3.2e-05 23.9 3.3 3.2e-05 23.9 3.3 2.9 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDJ87322.1 - 0.00086 19.1 6.8 0.00086 19.1 6.8 2.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ87322.1 - 0.0013 18.6 8.3 0.0013 18.6 8.3 3.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ87322.1 - 0.0018 18.4 6.9 0.0018 18.4 6.9 3.1 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING NHL PF01436.21 CDJ87322.1 - 0.0049 16.8 2.3 5.6 7.2 0.7 3.7 3 0 0 3 3 3 1 NHL repeat IL4 PF00727.18 CDJ87322.1 - 0.0051 17.0 0.9 0.019 15.2 0.9 2.0 1 0 0 1 1 1 1 Interleukin 4 Allexi_40kDa PF05549.11 CDJ87322.1 - 0.0061 16.1 1.1 0.01 15.4 1.1 1.2 1 0 0 1 1 1 1 Allexivirus 40kDa protein V_ATPase_I PF01496.19 CDJ87322.1 - 0.0093 14.0 2.8 0.013 13.5 2.8 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family LXG PF04740.12 CDJ87322.1 - 0.019 14.7 3.2 0.031 14.0 3.2 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily DUF948 PF06103.11 CDJ87322.1 - 0.021 15.1 3.5 0.52 10.6 0.3 2.8 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Apolipoprotein PF01442.18 CDJ87322.1 - 0.091 12.6 5.2 0.14 12.0 5.2 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 CDJ87322.1 - 0.11 12.6 4.7 0.26 11.3 4.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF349 PF03993.12 CDJ87322.1 - 0.12 12.7 1.4 0.26 11.6 1.4 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) Bet_v_1 PF00407.19 CDJ87322.1 - 0.24 11.3 1.0 0.62 9.9 1.0 1.7 1 0 0 1 1 1 0 Pathogenesis-related protein Bet v I family DUF4164 PF13747.6 CDJ87322.1 - 0.28 11.5 5.5 0.98 9.7 5.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) DLP_helical PF18709.1 CDJ87322.1 - 0.3 10.2 5.2 0.88 8.7 0.9 2.1 1 1 1 2 2 2 0 Dynamin-like helical domain FYVE PF01363.21 CDJ87322.1 - 0.34 11.1 15.5 3.1 8.0 3.6 2.8 2 0 0 2 2 2 0 FYVE zinc finger TPR_MLP1_2 PF07926.12 CDJ87322.1 - 0.41 10.7 4.0 0.2 11.7 1.6 1.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 CDJ87322.1 - 0.42 10.6 6.7 0.73 9.9 6.7 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KELK PF15796.5 CDJ87322.1 - 0.47 10.9 6.7 7.2 7.2 2.7 2.4 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase COG2 PF06148.11 CDJ87322.1 - 0.56 10.3 7.1 0.44 10.6 1.1 2.9 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 RRF PF01765.19 CDJ87322.1 - 0.64 10.0 5.3 1.3 9.0 5.3 1.4 1 0 0 1 1 1 0 Ribosome recycling factor zf-RING_4 PF14570.6 CDJ87322.1 - 1.3 8.8 19.0 0.021 14.6 4.6 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain APG6_N PF17675.1 CDJ87322.1 - 2.2 8.8 7.0 5 7.7 6.5 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region MFS_1 PF07690.16 CDJ87323.1 - 1.3e-07 30.9 6.6 6e-06 25.4 1.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF998 PF06197.13 CDJ87323.1 - 0.0021 17.7 3.0 0.0031 17.2 3.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF998) ACR_tran PF00873.19 CDJ87323.1 - 0.004 14.9 0.1 0.0053 14.5 0.1 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MerC PF03203.14 CDJ87323.1 - 0.04 14.4 0.3 0.068 13.6 0.3 1.5 1 1 0 1 1 1 0 MerC mercury resistance protein Kunitz_BPTI PF00014.23 CDJ87327.1 - 2e-16 59.9 2.8 2.3e-16 59.7 2.8 1.0 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Linker_histone PF00538.19 CDJ87329.1 - 2.6e-26 91.8 0.6 2.6e-26 91.8 0.6 2.3 2 1 0 2 2 2 1 linker histone H1 and H5 family RHH_1 PF01402.21 CDJ87329.1 - 0.13 12.2 0.1 1.9 8.6 0.1 2.3 1 1 1 2 2 2 0 Ribbon-helix-helix protein, copG family DUF1910 PF08928.10 CDJ87329.1 - 0.5 10.4 0.1 0.5 10.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) ABC2_membrane PF01061.24 CDJ87331.1 - 3.5e-38 131.1 26.3 8.2e-25 87.5 15.3 2.3 1 1 1 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 CDJ87331.1 - 0.00034 21.1 0.0 0.00064 20.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 CDJ87331.1 - 0.003 16.7 17.1 0.003 16.7 17.1 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein Gal-bind_lectin PF00337.22 CDJ87332.1 - 6e-94 310.7 0.0 3.8e-28 97.7 0.0 4.7 4 1 0 4 4 4 4 Galactoside-binding lectin Exo_endo_phos_2 PF14529.6 CDJ87333.1 - 9.6e-09 35.1 0.0 1.9e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 CDJ87333.1 - 1.1e-08 34.8 0.7 3.3e-07 30.0 0.1 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CDJ87333.1 - 0.00032 20.3 0.0 0.00065 19.3 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4351 PF14261.6 CDJ87333.1 - 0.019 15.0 0.0 5.6 7.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) PTCB-BRCT PF12738.7 CDJ87333.1 - 0.055 13.4 0.0 19 5.3 0.0 2.9 2 0 0 2 2 2 0 twin BRCT domain Ephrin PF00812.17 CDJ87334.1 - 1.2e-33 116.0 0.0 1.6e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 Ephrin PPR_2 PF13041.6 CDJ87337.1 - 4.1e-05 23.7 0.1 0.00027 21.1 0.0 2.5 2 1 1 3 3 3 1 PPR repeat family PPR_long PF17177.4 CDJ87337.1 - 0.021 14.2 0.1 0.069 12.5 0.1 1.9 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 CDJ87337.1 - 0.024 14.7 0.0 0.073 13.2 0.0 1.9 1 0 0 1 1 1 0 Pentatricopeptide repeat domain PPR PF01535.20 CDJ87337.1 - 0.25 11.7 2.7 17 5.9 0.1 3.6 3 0 0 3 3 3 0 PPR repeat Mad3_BUB1_I PF08311.12 CDJ87337.1 - 0.3 11.1 2.4 2.1 8.3 0.1 2.8 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 ACR_tran PF00873.19 CDJ87338.1 - 0.0054 14.5 0.0 0.0084 13.8 0.0 1.2 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family PPR_3 PF13812.6 CDJ87339.1 - 7.5e-05 22.7 0.0 0.0022 18.0 0.0 3.3 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR_long PF17177.4 CDJ87339.1 - 0.0003 20.2 1.4 0.0013 18.2 0.1 2.8 3 1 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP HHH_6 PF14579.6 CDJ87339.1 - 0.0019 18.4 1.0 1.9 8.8 0.0 4.3 4 0 0 4 4 4 1 Helix-hairpin-helix motif TPR_19 PF14559.6 CDJ87339.1 - 0.0029 18.1 9.0 0.95 10.0 2.6 5.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.9 CDJ87339.1 - 0.0058 16.4 4.4 0.04 13.6 1.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat-like domain MMR_HSR1_C PF08438.10 CDJ87339.1 - 0.014 16.0 0.1 0.086 13.4 0.1 2.5 1 0 0 1 1 1 0 GTPase of unknown function C-terminal PPR_1 PF12854.7 CDJ87339.1 - 0.057 13.1 0.7 1.4e+02 2.2 0.1 4.8 5 0 0 5 5 5 0 PPR repeat PPR PF01535.20 CDJ87339.1 - 0.062 13.6 3.3 76 3.9 0.1 5.7 5 0 0 5 5 5 0 PPR repeat PPR_2 PF13041.6 CDJ87339.1 - 0.43 10.8 1.9 70 3.7 0.1 4.7 4 1 0 4 4 4 0 PPR repeat family YtpI PF14007.6 CDJ87340.1 - 0.044 13.9 0.1 0.095 12.9 0.1 1.6 1 0 0 1 1 1 0 YtpI-like protein Metallophos PF00149.28 CDJ87341.1 - 8.8e-31 108.0 0.0 1.7e-30 107.1 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDJ87341.1 - 0.0022 18.4 0.5 0.0071 16.8 0.5 1.8 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 CDJ87341.1 - 0.041 14.1 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Astacin PF01400.24 CDJ87343.1 - 7.3e-27 94.2 4.8 2.8e-25 89.0 0.3 3.2 2 1 1 3 3 3 2 Astacin (Peptidase family M12A) Fibrinogen_C PF00147.18 CDJ87344.1 - 1.8e-41 142.4 4.9 3.2e-41 141.6 4.9 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Lectin_C PF00059.21 CDJ87344.1 - 1.1e-12 48.6 11.1 1.1e-12 48.6 11.1 2.9 2 1 1 3 3 3 1 Lectin C-type domain DUF1229 PF06797.11 CDJ87344.1 - 0.37 11.0 1.4 37 4.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1229) Fibrinogen_C PF00147.18 CDJ87345.1 - 0.00013 21.9 0.1 0.00014 21.8 0.1 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF2953 PF11167.8 CDJ87345.1 - 0.037 14.1 0.0 0.05 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) Fibrinogen_C PF00147.18 CDJ87346.1 - 1.7e-32 113.0 4.8 1.7e-32 113.0 4.8 1.6 2 0 0 2 2 2 1 Fibrinogen beta and gamma chains, C-terminal globular domain Lectin_C PF00059.21 CDJ87346.1 - 1.9e-12 47.9 11.6 1.9e-12 47.9 11.6 2.4 2 1 0 2 2 2 1 Lectin C-type domain DUF1229 PF06797.11 CDJ87346.1 - 0.44 10.8 1.9 28 4.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1229) TF_AP-2 PF03299.14 CDJ87347.1 - 2e-69 233.6 0.0 2.5e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 Transcription factor AP-2 TMEM208_SND2 PF05620.11 CDJ87348.1 - 5e-32 111.0 0.0 1e-31 110.0 0.0 1.5 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 XTBD PF11952.8 CDJ87348.1 - 3.6e-19 68.3 0.1 1.1e-18 66.8 0.1 1.8 1 0 0 1 1 1 1 XRN-Two Binding Domain, XTBD mit_SMPDase PF14724.6 CDJ87348.1 - 4.1e-10 38.3 0.6 2.6e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial-associated sphingomyelin phosphodiesterase AgrB PF04647.15 CDJ87348.1 - 0.013 14.8 2.3 0.053 12.8 0.0 2.5 2 0 0 2 2 2 0 Accessory gene regulator B NTF2 PF02136.20 CDJ87349.1 - 6.3e-33 113.9 0.0 7.2e-33 113.7 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.6 CDJ87349.1 - 0.079 12.1 0.0 0.43 9.7 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) DAP PF15228.6 CDJ87351.1 - 3.8e-16 60.1 4.2 5.2e-16 59.6 4.2 1.2 1 0 0 1 1 1 1 Death-associated protein BTB PF00651.31 CDJ87352.1 - 0.02 15.1 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain DUF1129 PF06570.11 CDJ87353.1 - 1.6 8.2 3.9 1.6 8.1 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) XPG_N PF00752.17 CDJ87355.1 - 7.8e-34 116.2 0.0 1.7e-33 115.1 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CDJ87355.1 - 4.8e-29 100.6 0.1 1.1e-28 99.4 0.1 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 CDJ87355.1 - 8.1e-08 32.8 0.0 3.3e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 CDJ87355.1 - 0.02 15.5 0.0 0.079 13.6 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain 5_3_exonuc_N PF02739.16 CDJ87355.1 - 0.026 14.4 0.1 0.092 12.6 0.1 1.8 1 1 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain HHH_2 PF12826.7 CDJ87355.1 - 0.076 13.1 0.0 0.25 11.4 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif RNA_pol_3_Rpc31 PF11705.8 CDJ87356.1 - 8.7e-21 75.2 2.1 1.2e-20 74.8 2.1 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Peptidase_M41 PF01434.18 CDJ87357.1 - 1.3e-18 67.5 0.0 2e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 CARD PF00619.21 CDJ87357.1 - 0.08 13.0 0.6 0.12 12.5 0.6 1.2 1 0 0 1 1 1 0 Caspase recruitment domain Leu_zip PF15294.6 CDJ87358.1 - 0.044 13.3 0.1 0.048 13.2 0.1 1.1 1 0 0 1 1 1 0 Leucine zipper CorA PF01544.18 CDJ87358.1 - 0.1 11.9 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DivIC PF04977.15 CDJ87358.1 - 0.22 11.3 0.1 0.35 10.7 0.1 1.2 1 0 0 1 1 1 0 Septum formation initiator Activin_recp PF01064.23 CDJ87360.1 - 0.011 16.9 4.3 0.011 16.9 4.3 1.9 2 0 0 2 2 2 0 Activin types I and II receptor domain UPAR_LY6_2 PF16975.5 CDJ87360.1 - 0.019 15.1 3.4 2 8.7 1.2 2.2 2 0 0 2 2 2 0 Ly6/PLAUR domain-containing protein 6, Lypd6 CDC50 PF03381.15 CDJ87361.1 - 4.1e-47 161.0 0.0 5.7e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF1198 PF06711.11 CDJ87362.1 - 0.086 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1198) Na_H_Exchanger PF00999.21 CDJ87363.1 - 7.4e-81 271.9 45.7 8.8e-81 271.6 45.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Glyco_transf_92 PF01697.27 CDJ87364.1 - 3.1e-27 95.9 0.0 4e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 92 PI31_Prot_N PF11566.8 CDJ87364.1 - 0.14 11.9 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 PI31 proteasome regulator N-terminal RTTN_N PF14726.6 CDJ87365.1 - 0.011 16.6 0.2 8.6 7.2 0.0 2.9 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning U3snoRNP10 PF12397.8 CDJ87365.1 - 0.096 13.0 1.6 0.29 11.5 1.6 1.8 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 LRR_6 PF13516.6 CDJ87365.1 - 6.1 7.2 8.9 30 5.0 0.3 5.3 5 0 0 5 5 5 0 Leucine Rich repeat KLRAQ PF10205.9 CDJ87366.1 - 0.0059 16.8 2.3 0.012 15.8 0.6 2.1 2 0 0 2 2 2 1 Predicted coiled-coil domain-containing protein HLH PF00010.26 CDJ87367.1 - 9.5e-13 47.9 0.1 1.7e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3262 PF11660.8 CDJ87368.1 - 0.024 15.0 0.1 0.056 13.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) Activin_recp PF01064.23 CDJ87369.1 - 2.9e-05 25.0 11.5 3.8e-05 24.7 11.5 1.1 1 0 0 1 1 1 1 Activin types I and II receptor domain Toxin_TOLIP PF00087.21 CDJ87369.1 - 3.8 7.8 17.1 20 5.5 16.9 2.0 1 1 0 1 1 1 0 Snake toxin and toxin-like protein BTB_2 PF02214.22 CDJ87371.1 - 1.2e-06 28.8 0.0 2.1e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 BTB/POZ domain EF-hand_7 PF13499.6 CDJ87372.1 - 3.5e-06 27.4 0.0 0.00034 21.0 0.0 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ87372.1 - 1.5e-05 24.7 0.0 0.00026 20.8 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ87372.1 - 2.5e-05 23.8 0.0 0.014 15.3 0.0 3.4 3 1 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 CDJ87372.1 - 3.8e-05 22.9 0.1 0.17 11.5 0.0 3.5 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 CDJ87372.1 - 0.08 13.3 0.0 20 5.6 0.0 2.4 2 1 0 2 2 2 0 EF-hand domain EF-hand_5 PF13202.6 CDJ87372.1 - 0.16 11.6 0.2 14 5.4 0.0 3.1 3 0 0 3 3 3 0 EF hand Yippee-Mis18 PF03226.14 CDJ87373.1 - 5.6e-14 52.2 1.4 7.4e-14 51.8 1.4 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly ATPgrasp_YheCD PF14398.6 CDJ87373.1 - 0.016 14.5 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 YheC/D like ATP-grasp Jas PF16135.5 CDJ87373.1 - 0.024 14.8 1.3 0.027 14.6 0.4 1.6 1 1 0 1 1 1 0 TPL-binding domain in jasmonate signalling SDF PF00375.18 CDJ87374.1 - 7.4e-121 403.8 30.3 8.8e-121 403.6 30.3 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF4199 PF13858.6 CDJ87374.1 - 0.46 10.9 10.3 2.2 8.6 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF4199) LBP_BPI_CETP_C PF02886.17 CDJ87375.1 - 5.4e-29 101.3 0.0 8.1e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain Na_sulph_symp PF00939.19 CDJ87376.1 - 1.7e-12 47.2 1.7 1.6e-08 34.0 0.4 2.3 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CDJ87376.1 - 0.00063 19.0 1.9 0.00065 19.0 0.2 1.7 2 1 0 2 2 2 1 Citrate transporter Na_sulph_symp PF00939.19 CDJ87377.1 - 1.7e-08 34.0 1.3 1.8e-08 33.9 1.3 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region FimH_man-bind PF09160.10 CDJ87378.1 - 0.032 13.9 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 FimH, mannose binding DUF4173 PF13777.6 CDJ87379.1 - 0.3 10.5 12.6 0.039 13.4 3.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) eRF1_1 PF03463.15 CDJ87380.1 - 1.2e-51 174.1 0.1 1.9e-51 173.4 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 CDJ87380.1 - 1.3e-31 109.6 0.1 2.5e-31 108.7 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CDJ87380.1 - 3.6e-23 82.2 0.0 7.7e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 DUF5492 PF17596.2 CDJ87380.1 - 0.02 15.2 0.0 0.058 13.7 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5492) CbiA PF01656.23 CDJ87380.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain bZIP_2 PF07716.15 CDJ87381.1 - 3.6e-09 36.5 15.0 3.6e-09 36.5 15.0 2.1 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CDJ87381.1 - 3.3e-08 33.5 17.2 2.2e-07 30.9 16.0 2.5 1 1 1 2 2 2 2 bZIP transcription factor bZIP_Maf PF03131.17 CDJ87381.1 - 5e-06 27.0 15.4 9.8e-06 26.0 15.4 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor CASP_C PF08172.12 CDJ87381.1 - 0.00018 21.0 4.1 0.00026 20.4 4.1 1.2 1 0 0 1 1 1 1 CASP C terminal ZapB PF06005.12 CDJ87381.1 - 0.0017 18.7 8.8 0.0017 18.7 8.8 2.4 2 0 0 2 2 2 1 Cell division protein ZapB V_ATPase_I PF01496.19 CDJ87381.1 - 0.0058 14.6 4.4 0.0074 14.3 4.4 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Fmp27_WPPW PF10359.9 CDJ87381.1 - 0.0099 14.8 1.2 0.012 14.5 1.2 1.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain GAS PF13851.6 CDJ87381.1 - 0.057 12.8 11.3 0.097 12.0 11.3 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding HALZ PF02183.18 CDJ87381.1 - 0.095 12.9 4.8 0.25 11.6 4.8 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper ADIP PF11559.8 CDJ87381.1 - 0.14 12.3 15.4 0.23 11.6 15.4 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Na_trans_assoc PF06512.13 CDJ87381.1 - 0.17 12.2 5.0 0.31 11.3 5.0 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated TSC22 PF01166.18 CDJ87381.1 - 0.27 11.6 4.8 0.95 9.8 4.8 2.0 1 0 0 1 1 1 0 TSC-22/dip/bun family UPF0242 PF06785.11 CDJ87381.1 - 0.71 9.9 11.6 1.2 9.2 10.8 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Rootletin PF15035.6 CDJ87381.1 - 1.8 8.6 16.6 0.79 9.7 13.1 1.9 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Motile_Sperm PF00635.26 CDJ87382.1 - 1.4e-14 53.8 0.0 2e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ABC_tran PF00005.27 CDJ87383.2 - 1.6e-47 161.5 0.1 6.9e-25 88.2 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CDJ87383.2 - 2.4e-30 105.8 10.8 3.2e-29 102.1 10.8 2.3 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 CDJ87383.2 - 9.3e-20 71.6 0.4 8.9e-07 29.0 0.0 4.4 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDJ87383.2 - 7.4e-05 22.3 0.0 0.5 9.8 0.0 3.8 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain DUF4162 PF13732.6 CDJ87383.2 - 0.00016 22.3 0.1 0.019 15.7 0.0 3.3 3 1 0 3 3 3 1 Domain of unknown function (DUF4162) AAA_23 PF13476.6 CDJ87383.2 - 0.0099 16.4 10.7 0.051 14.1 0.3 3.1 3 1 0 3 3 3 2 AAA domain SbcCD_C PF13558.6 CDJ87383.2 - 0.011 16.0 0.0 9.9 6.5 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 CDJ87383.2 - 0.015 15.0 2.0 1.8 8.4 0.1 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CDJ87383.2 - 0.026 14.6 0.1 11 6.1 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 CDJ87383.2 - 0.12 11.6 0.1 10 5.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin RCC1_2 PF13540.6 CDJ87383.2 - 0.14 12.0 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat SRP54 PF00448.22 CDJ87383.2 - 0.24 11.0 1.2 21 4.7 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_13 PF13166.6 CDJ87383.2 - 0.27 9.8 1.5 3 6.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain RVT_1 PF00078.27 CDJ87384.1 - 6e-24 84.8 0.0 7.9e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_hydro_31 PF01055.26 CDJ87385.1 - 8.3e-11 41.7 0.1 1.1e-10 41.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF5110 PF17137.4 CDJ87385.1 - 4.8e-06 26.8 0.1 9.3e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Phenol_Hydrox PF02332.18 CDJ87385.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 Methane/Phenol/Toluene Hydroxylase Collagen PF01391.18 CDJ87386.1 - 4.5e-38 128.8 105.5 3.3e-10 39.6 23.4 4.2 1 1 3 4 4 4 4 Collagen triple helix repeat (20 copies) DUF4349 PF14257.6 CDJ87386.1 - 0.21 11.0 0.2 0.28 10.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) AT_hook PF02178.19 CDJ87387.1 - 0.041 13.8 66.1 0.2 11.6 4.7 6.8 6 0 0 6 6 6 0 AT hook motif Slx4 PF09494.10 CDJ87388.1 - 0.012 15.5 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 Slx4 endonuclease SAP PF02037.27 CDJ87388.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 SAP domain LEM PF03020.15 CDJ87388.1 - 0.14 11.8 0.0 0.43 10.2 0.0 1.9 1 0 0 1 1 1 0 LEM domain zf-CCHC_4 PF14392.6 CDJ87390.1 - 0.078 12.7 1.5 0.17 11.6 1.5 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 CDJ87390.1 - 0.18 12.0 2.5 0.33 11.1 2.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Cyt-b5 PF00173.28 CDJ87391.1 - 4.1e-13 49.3 0.0 5.5e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain OATP PF03137.20 CDJ87393.1 - 1.1 7.5 5.2 1.2 7.3 5.2 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_M24 PF00557.24 CDJ87395.1 - 1e-53 182.2 0.0 1.1e-28 100.4 0.1 2.3 1 1 1 2 2 2 2 Metallopeptidase family M24 Zn_ribbon_17 PF17120.5 CDJ87396.1 - 0.022 14.4 2.4 0.18 11.4 0.6 2.4 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-HYPF PF07503.12 CDJ87397.1 - 0.17 11.7 3.3 1.4 8.8 0.1 3.0 1 1 2 3 3 3 0 HypF finger Alpha-amylase PF00128.24 CDJ87398.1 - 3.1e-15 56.6 0.0 5.1e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain SpoU_methylas_C PF12105.8 CDJ87398.1 - 0.055 13.2 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal NCE101 PF11654.8 CDJ87398.1 - 0.18 11.5 0.4 0.32 10.8 0.4 1.4 1 0 0 1 1 1 0 Non-classical export protein 1 OAD_gamma PF04277.13 CDJ87399.1 - 0.018 15.6 0.1 0.047 14.3 0.1 1.7 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Forkhead_N PF08430.12 CDJ87400.1 - 2 9.1 7.1 2.2 8.9 7.1 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region Apt1 PF10351.9 CDJ87403.1 - 6.5 5.5 11.8 8.5 5.1 11.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain HpcH_HpaI PF03328.14 CDJ87404.1 - 1.8e-66 223.5 0.0 2.6e-66 222.9 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 CDJ87404.1 - 9.7e-13 48.0 0.0 4.3e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold ATG13 PF10033.9 CDJ87405.1 - 0.00012 21.8 0.1 0.67 9.6 0.1 3.1 2 1 0 2 2 2 2 Autophagy-related protein 13 GalKase_gal_bdg PF10509.9 CDJ87406.1 - 1.6e-07 30.8 0.2 3.5e-07 29.7 0.2 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 CDJ87406.1 - 1.1e-06 28.8 0.3 2.9e-06 27.4 0.3 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain Aha1_N PF09229.11 CDJ87408.1 - 3.2e-36 124.6 0.3 6.6e-36 123.5 0.1 1.6 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 CDJ87408.1 - 2.5e-17 63.3 0.0 6.8e-17 61.9 0.0 1.8 1 1 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein RVT_1 PF00078.27 CDJ87410.1 - 1.2e-36 126.3 0.0 1.9e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CDJ87411.1 - 2.3e-09 37.1 0.0 2.5e-09 37.0 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Na_sulph_symp PF00939.19 CDJ87412.1 - 4.2e-30 105.2 6.7 4.3e-30 105.2 6.7 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CDJ87412.1 - 1.6e-12 47.2 1.6 1.6e-12 47.2 1.6 2.0 1 1 1 2 2 2 2 Citrate transporter MatC_N PF07158.11 CDJ87412.1 - 0.0068 16.4 0.5 0.0068 16.4 0.5 1.7 2 0 0 2 2 2 1 Dicarboxylate carrier protein MatC N-terminus GntP_permease PF02447.16 CDJ87412.1 - 0.12 11.0 8.9 0.3 9.7 8.9 1.6 1 1 0 1 1 1 0 GntP family permease LBP_BPI_CETP_C PF02886.17 CDJ87413.1 - 3.1e-21 75.9 0.0 4.9e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain SDF PF00375.18 CDJ87414.1 - 2.4e-88 296.8 18.5 2.9e-88 296.5 18.5 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family MyTH4 PF00784.17 CDJ87415.1 - 5.5e-23 81.5 0.1 1.9e-22 79.8 0.1 2.0 1 0 0 1 1 1 1 MyTH4 domain PH PF00169.29 CDJ87415.1 - 8.6e-20 71.2 2.1 6.1e-10 39.5 0.3 3.4 3 0 0 3 3 3 2 PH domain FERM_M PF00373.18 CDJ87415.1 - 2.1e-10 41.0 0.0 8.8e-10 39.0 0.0 2.1 1 0 0 1 1 1 1 FERM central domain PH_11 PF15413.6 CDJ87415.1 - 0.0015 19.0 6.9 0.0037 17.7 0.6 3.2 3 0 0 3 3 3 1 Pleckstrin homology domain RBD PF02196.15 CDJ87415.1 - 0.034 14.2 0.0 0.54 10.4 0.0 2.5 2 0 0 2 2 2 0 Raf-like Ras-binding domain PH_9 PF15410.6 CDJ87415.1 - 0.041 14.3 2.0 0.2 12.1 1.1 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain PH_2 PF08458.10 CDJ87415.1 - 0.047 14.1 0.3 0.21 11.9 0.1 2.2 2 0 0 2 2 2 0 Plant pleckstrin homology-like region GrpE PF01025.19 CDJ87415.1 - 0.27 10.9 1.9 0.5 10.0 1.9 1.3 1 0 0 1 1 1 0 GrpE RasGEF PF00617.19 CDJ87416.1 - 7.7e-53 179.3 0.1 1.6e-52 178.3 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain PDZ_6 PF17820.1 CDJ87416.1 - 1.6e-11 43.9 0.0 5.6e-11 42.1 0.0 1.9 2 0 0 2 2 2 1 PDZ domain RasGEF_N PF00618.20 CDJ87416.1 - 6.8e-11 42.3 0.6 3.2e-09 37.0 0.6 2.7 1 1 0 1 1 1 1 RasGEF N-terminal motif PDZ PF00595.24 CDJ87416.1 - 9.1e-11 42.0 0.0 2.1e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain RA PF00788.23 CDJ87416.1 - 1.1e-07 32.4 0.1 2.6e-07 31.2 0.1 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PDZ_2 PF13180.6 CDJ87416.1 - 6e-05 23.3 0.0 0.00016 22.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain cNMP_binding PF00027.29 CDJ87416.1 - 0.01 15.9 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 CDJ87416.1 - 0.17 11.6 0.1 0.35 10.6 0.1 1.5 1 0 0 1 1 1 0 Cupin domain Isochorismatase PF00857.20 CDJ87417.1 - 8.2e-18 65.2 0.4 2.9e-14 53.6 0.3 2.1 2 0 0 2 2 2 2 Isochorismatase family AceK PF06315.11 CDJ87417.1 - 0.04 12.4 0.1 0.067 11.7 0.1 1.3 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) Isochorismatase PF00857.20 CDJ87418.1 - 4.3e-06 27.0 0.0 4.6e-06 26.9 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.20 CDJ87419.1 - 4.7e-22 79.0 0.0 2.4e-21 76.7 0.0 1.8 1 1 0 1 1 1 1 Isochorismatase family OpuAC PF04069.12 CDJ87419.1 - 0.048 13.2 0.0 0.057 13.0 0.0 1.1 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system Evr1_Alr PF04777.13 CDJ87420.1 - 3.2e-21 75.7 1.8 1.2e-20 73.9 0.4 2.6 3 0 0 3 3 3 1 Erv1 / Alr family Thioredoxin PF00085.20 CDJ87420.1 - 6.7e-18 64.6 0.0 9.9e-17 60.8 0.1 2.5 2 0 0 2 2 2 1 Thioredoxin QSOX_Trx1 PF18108.1 CDJ87420.1 - 9.7e-05 22.5 0.0 0.00023 21.3 0.0 1.6 1 0 0 1 1 1 1 QSOX Trx-like domain Thioredoxin_8 PF13905.6 CDJ87420.1 - 0.00018 21.8 0.2 0.0015 18.8 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin-like FAD_SOX PF18371.1 CDJ87420.1 - 0.0012 19.2 0.2 0.016 15.5 0.0 2.8 3 1 1 4 4 4 1 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Thioredoxin_9 PF14595.6 CDJ87420.1 - 0.015 15.1 0.0 0.044 13.5 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.10 CDJ87420.1 - 0.023 14.4 0.1 0.049 13.3 0.1 1.5 1 0 0 1 1 1 0 Redoxin Thioredoxin_7 PF13899.6 CDJ87420.1 - 0.058 13.6 0.1 0.25 11.6 0.2 2.1 2 0 0 2 2 2 0 Thioredoxin-like Trypan_PARP PF05887.11 CDJ87421.1 - 0.048 13.6 21.0 0.085 12.8 21.0 1.4 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) 7tm_2 PF00002.24 CDJ87422.1 - 2.1e-58 197.5 11.2 2.8e-58 197.1 11.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 CDJ87422.1 - 6.1e-10 39.3 4.3 1.1e-09 38.4 4.3 1.5 1 0 0 1 1 1 1 Hormone receptor domain ELO PF01151.18 CDJ87423.1 - 6.8e-64 215.8 23.3 8.4e-64 215.5 23.3 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Methyltransf_23 PF13489.6 CDJ87424.1 - 6e-16 58.7 0.0 9.5e-16 58.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ87424.1 - 8.8e-15 55.3 0.0 7.7e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ87424.1 - 2.6e-14 53.7 0.0 4.1e-13 49.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ87424.1 - 7.8e-12 45.7 0.0 5.7e-09 36.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ87424.1 - 3.4e-10 39.9 0.0 6.3e-10 39.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.11 CDJ87424.1 - 0.00025 20.7 0.0 0.00045 19.9 0.0 1.4 1 1 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 CDJ87424.1 - 0.00031 20.3 0.0 0.00046 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 CDJ87424.1 - 0.00033 20.1 0.0 0.0017 17.8 0.0 2.1 2 0 0 2 2 2 1 Tellurite resistance protein TehB CheR PF01739.18 CDJ87424.1 - 0.00085 18.9 0.0 0.052 13.0 0.0 2.2 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain CMAS PF02353.20 CDJ87424.1 - 0.0043 16.4 0.0 0.0071 15.7 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.6 CDJ87424.1 - 0.015 16.3 0.0 0.052 14.6 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 CDJ87424.1 - 0.015 14.5 0.0 0.027 13.6 0.0 1.4 1 1 0 1 1 1 0 NNMT/PNMT/TEMT family DUF938 PF06080.12 CDJ87424.1 - 0.16 11.7 0.0 0.47 10.2 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Methyltr_RsmB-F PF01189.17 CDJ87425.1 - 1.3e-31 109.8 0.0 1.8e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 CDJ87425.1 - 0.00057 19.7 0.0 0.0013 18.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ87425.1 - 0.001 19.7 0.0 0.0026 18.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 CDJ87425.1 - 0.043 13.9 0.0 0.065 13.3 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Fibrillarin PF01269.17 CDJ87425.1 - 0.046 12.8 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Fibrillarin Trimer_CC PF08954.11 CDJ87425.1 - 0.79 9.3 3.2 0.98 9.0 0.3 2.5 3 0 0 3 3 3 0 Trimerisation motif PUF PF00806.19 CDJ87426.1 - 3.8e-66 215.2 7.4 3.6e-09 35.8 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 CDJ87426.1 - 0.00056 20.3 1.2 3.4 8.0 0.1 4.1 1 1 3 4 4 4 3 CPL (NUC119) domain ArAE_1_C PF11728.8 CDJ87426.1 - 0.0015 18.5 1.6 0.0015 18.5 0.2 1.7 2 0 0 2 2 2 1 Putative aromatic acid exporter C-terminal domain sCache_2 PF17200.4 CDJ87426.1 - 0.011 15.6 0.4 0.25 11.2 0.0 3.0 4 0 0 4 4 4 0 Single Cache domain 2 PLN_propep PF16485.5 CDJ87426.1 - 0.045 13.5 2.9 3.2 7.5 0.1 3.2 3 0 0 3 3 3 0 Protealysin propeptide dCache_2 PF08269.11 CDJ87426.1 - 0.11 11.7 0.1 0.43 9.7 0.0 1.9 2 0 0 2 2 2 0 Cache domain SapB_2 PF03489.17 CDJ87426.1 - 0.6 10.3 2.6 6.2 7.0 0.1 3.7 4 0 0 4 4 4 0 Saposin-like type B, region 2 ATP-synt_ab PF00006.25 CDJ87427.1 - 2.1e-63 213.8 0.1 5.4e-63 212.5 0.1 1.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CDJ87427.1 - 4.5e-11 43.1 1.4 8.8e-11 42.2 1.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF4258 PF14076.6 CDJ87427.1 - 0.13 12.7 0.3 0.33 11.4 0.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4258) WD40 PF00400.32 CDJ87429.1 - 1.1e-07 32.4 5.3 0.0085 16.9 0.1 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ87429.1 - 0.00061 20.0 0.0 1 9.7 0.0 3.5 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 CDJ87429.1 - 0.0078 15.6 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 CPSF A subunit region WD40_alt PF14077.6 CDJ87429.1 - 0.015 15.2 0.2 0.031 14.1 0.2 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif Serglycin PF04360.12 CDJ87429.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Serglycin Lep_receptor_Ig PF06328.11 CDJ87429.1 - 0.11 12.5 0.0 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 Ig-like C2-type domain FixS PF03597.15 CDJ87429.1 - 0.14 11.9 0.2 0.28 10.9 0.2 1.5 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Piwi PF02171.17 CDJ87430.1 - 7.1e-64 215.9 0.7 8.2e-64 215.7 0.7 1.0 1 0 0 1 1 1 1 Piwi domain HbrB PF08539.11 CDJ87431.1 - 0.0002 21.4 3.8 0.0049 16.9 0.1 2.4 1 1 1 2 2 2 2 HbrB-like wnt PF00110.19 CDJ87432.1 - 2e-113 379.0 19.7 2.3e-113 378.8 19.7 1.0 1 0 0 1 1 1 1 wnt family Chitin_synth_2 PF03142.15 CDJ87433.1 - 1.1e-28 100.2 3.7 1.2e-25 90.2 0.2 2.3 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CDJ87433.1 - 1.4e-13 51.2 4.6 5.9e-13 49.2 4.6 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CDJ87433.1 - 2.3e-06 27.7 0.0 4.8e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CDJ87433.1 - 0.039 13.8 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Asp PF00026.23 CDJ87434.1 - 1.5e-45 156.0 1.7 1.8e-45 155.8 1.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ87434.1 - 8e-14 52.3 2.0 2e-07 31.4 1.1 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal YgaB PF14182.6 CDJ87435.1 - 0.37 11.2 2.1 1.1 9.7 2.1 1.8 1 0 0 1 1 1 0 YgaB-like protein Recep_L_domain PF01030.24 CDJ87438.1 - 5.8e-13 48.9 0.5 5.7e-06 26.4 0.0 3.4 3 1 0 3 3 3 2 Receptor L domain RnlA_toxin PF15935.5 CDJ87438.1 - 0.05 13.4 0.3 0.082 12.7 0.3 1.3 1 0 0 1 1 1 0 RNase LS, bacterial toxin Utp21 PF04192.12 CDJ87438.1 - 0.12 11.9 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain V_ATPase_I PF01496.19 CDJ87440.1 - 0.08 10.9 0.5 0.1 10.5 0.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 CDJ87440.1 - 0.086 11.9 2.2 0.13 11.4 2.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TcpQ PF10671.9 CDJ87441.1 - 0.011 15.8 0.7 0.2 11.8 0.3 2.3 2 0 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q DUF629 PF04780.12 CDJ87441.1 - 0.013 14.1 0.2 0.017 13.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) DUF349 PF03993.12 CDJ87441.1 - 0.16 12.3 3.4 0.57 10.5 3.4 1.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) RT_RNaseH_2 PF17919.1 CDJ87442.1 - 1.8e-34 117.7 0.0 1.4e-33 114.9 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ87442.1 - 1.5e-32 112.0 0.1 1.1e-31 109.2 0.0 2.5 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ87442.1 - 3.4e-15 55.9 0.3 6.3e-15 55.0 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDJ87442.1 - 2.3e-08 34.2 0.0 1.3e-07 31.8 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain GCIP PF13324.6 CDJ87443.1 - 0.026 14.1 3.2 0.03 13.9 3.2 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF4440 PF14534.6 CDJ87444.1 - 1.4e-05 25.4 0.3 0.0021 18.5 0.3 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4440) NopRA1 PF16201.5 CDJ87444.1 - 0.044 13.4 0.0 0.053 13.1 0.0 1.1 1 0 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 DDE_3 PF13358.6 CDJ87445.1 - 4.8e-16 58.8 5.5 1.3e-07 31.5 0.7 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease DUF4498 PF14926.6 CDJ87445.1 - 0.00058 19.3 0.4 0.35 10.1 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4498) LSPR PF06049.12 CDJ87445.1 - 0.0044 16.6 2.7 2.4 8.3 0.2 2.5 2 0 0 2 2 2 2 Coagulation Factor V LSPD Repeat TerB PF05099.13 CDJ87445.1 - 0.1 12.5 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TerB Blt1_C PF17183.4 CDJ87445.1 - 1.1 8.9 3.8 0.98 9.1 0.2 2.5 3 0 0 3 3 3 0 Get5 carboxyl domain SCNM1_acidic PF15805.5 CDJ87445.1 - 2.5 7.9 5.3 23 4.8 0.1 2.8 3 0 0 3 3 3 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 Peptidase_M13 PF01431.21 CDJ87446.1 - 1.8e-83 279.2 0.1 3.9e-48 163.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M13 Peptidase_M13_N PF05649.13 CDJ87446.1 - 4.2e-16 59.6 0.0 6.3e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 YdjO PF14169.6 CDJ87446.1 - 0.068 12.9 4.8 4.3 7.1 0.2 2.6 3 0 0 3 3 3 0 Cold-inducible protein YdjO Metallophos PF00149.28 CDJ87447.1 - 1.3e-29 104.2 0.1 1.6e-29 103.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Shisa PF13908.6 CDJ87451.1 - 0.00056 20.2 0.1 0.00088 19.6 0.1 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator SF1-HH PF16275.5 CDJ87451.1 - 0.19 12.1 1.0 0.44 10.9 1.0 1.5 1 1 0 1 1 1 0 Splicing factor 1 helix-hairpin domain C2 PF00168.30 CDJ87452.1 - 4.7e-13 49.3 0.1 9e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 C2 domain Epiglycanin_C PF14654.6 CDJ87452.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region C2 PF00168.30 CDJ87453.1 - 3.1e-27 94.9 0.3 5.6e-21 74.8 0.1 2.1 2 0 0 2 2 2 2 C2 domain RrnaAD PF00398.20 CDJ87454.1 - 1.4e-62 211.2 0.1 1.9e-62 210.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CDJ87454.1 - 7.2e-08 33.0 0.0 1.3e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ87454.1 - 2.5e-05 24.8 0.0 5.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ87454.1 - 0.00016 21.5 0.0 0.00024 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CDJ87454.1 - 0.0002 20.9 0.0 0.00032 20.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 CDJ87454.1 - 0.00022 21.1 0.0 0.00036 20.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 CDJ87454.1 - 0.00024 20.9 0.0 0.0004 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ87454.1 - 0.00061 19.4 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 CDJ87454.1 - 0.0014 19.3 0.0 0.0027 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 CDJ87454.1 - 0.0069 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Ubie_methyltran PF01209.18 CDJ87454.1 - 0.0075 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 CDJ87454.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CDJ87454.1 - 0.019 14.2 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase LCM PF04072.14 CDJ87454.1 - 0.022 14.7 0.0 0.57 10.1 0.0 2.2 2 0 0 2 2 2 0 Leucine carboxyl methyltransferase Methyltransf_2 PF00891.18 CDJ87454.1 - 0.026 13.8 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Met_10 PF02475.16 CDJ87454.1 - 0.049 13.4 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_4 PF02390.17 CDJ87454.1 - 0.063 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.18 CDJ87454.1 - 0.067 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_28 PF02636.17 CDJ87454.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RVT_1 PF00078.27 CDJ87455.1 - 2e-16 60.2 0.0 2.7e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DeoC PF01791.9 CDJ87455.1 - 0.21 11.2 0.0 0.57 9.7 0.0 1.7 2 0 0 2 2 2 0 DeoC/LacD family aldolase An_peroxidase PF03098.15 CDJ87456.1 - 5.1e-42 144.1 0.0 1.7e-40 139.1 0.0 2.0 1 1 1 2 2 2 2 Animal haem peroxidase Apolipoprotein PF01442.18 CDJ87458.1 - 4e-25 88.8 101.9 6.6e-07 29.4 30.3 8.6 1 1 5 7 7 7 7 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 CDJ87458.1 - 3.9e-18 65.8 162.4 0.0015 19.1 3.6 17.3 1 1 16 18 18 18 12 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 CDJ87458.1 - 2.7e-09 37.3 112.9 0.00066 19.8 31.1 10.4 2 1 10 12 12 12 8 Apolipophorin-III precursor (apoLp-III) LEA_4 PF02987.16 CDJ87458.1 - 1.8e-05 24.7 19.7 0.00018 21.5 6.1 25.5 17 5 12 29 29 29 9 Late embryogenesis abundant protein YtxH PF12732.7 CDJ87458.1 - 0.00091 19.7 212.2 16 6.1 3.1 19.6 1 1 4 5 5 5 1 YtxH-like protein SOAR PF16533.5 CDJ87458.1 - 0.0047 16.9 6.3 0.0047 16.9 6.3 8.4 3 2 7 10 10 10 2 STIM1 Orai1-activating region Baculo_PEP_C PF04513.12 CDJ87458.1 - 0.39 10.8 4.3 12 5.9 0.5 4.8 5 1 1 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 CDJ87458.1 - 1.3 6.9 28.5 0.015 13.3 11.4 3.8 2 2 1 4 4 4 0 Prominin Exonuc_VII_L PF02601.15 CDJ87458.1 - 4 6.9 54.4 4.2e+03 -3.0 0.0 5.8 2 1 0 2 2 2 0 Exonuclease VII, large subunit FlaC_arch PF05377.11 CDJ87458.1 - 6.7 7.2 20.3 3.4 8.1 5.9 4.1 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Y_phosphatase PF00102.27 CDJ87459.1 - 2.4e-35 122.2 0.0 3.6e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Acetyltransf_1 PF00583.25 CDJ87460.1 - 0.0003 21.0 0.0 0.00089 19.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CDJ87460.1 - 0.014 15.3 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_7 PF13508.7 CDJ87460.1 - 0.032 14.7 0.0 0.063 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.10 CDJ87460.1 - 0.033 14.4 0.0 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region DUF1758 PF05585.12 CDJ87461.1 - 0.00016 21.5 0.3 0.00036 20.3 0.3 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Mo-nitro_C PF06967.11 CDJ87461.1 - 0.13 12.3 0.2 2.9 7.9 0.1 2.3 2 0 0 2 2 2 0 Mo-dependent nitrogenase C-terminus Ufm1 PF03671.14 CDJ87462.1 - 4.5e-31 106.8 0.2 7.5e-31 106.1 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin fold modifier 1 protein ANP PF00212.18 CDJ87462.1 - 0.11 12.8 0.5 0.16 12.2 0.5 1.2 1 0 0 1 1 1 0 Atrial natriuretic peptide QueC PF06508.13 CDJ87463.1 - 0.36 10.3 3.3 7.3 6.0 0.0 2.2 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Clat_adaptor_s PF01217.20 CDJ87465.1 - 0.0023 17.8 0.3 0.0023 17.8 0.3 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Piwi PF02171.17 CDJ87466.1 - 4.9e-81 272.3 0.5 9.6e-81 271.3 0.3 1.5 2 0 0 2 2 2 1 Piwi domain PAZ PF02170.22 CDJ87466.1 - 8e-25 87.2 0.1 2e-24 86.0 0.1 1.6 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 CDJ87466.1 - 0.016 14.9 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 Argonaute linker 1 domain AMNp_N PF10423.9 CDJ87466.1 - 0.082 12.5 0.1 8.3 6.0 0.0 2.8 3 0 0 3 3 3 0 Bacterial AMP nucleoside phosphorylase N-terminus Collagen PF01391.18 CDJ87467.1 - 7.6e-16 57.6 39.3 4.2e-08 32.8 17.1 2.2 2 0 0 2 2 2 2 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ87467.1 - 1.2e-08 34.8 0.1 1.7e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain DUF1940 PF09155.10 CDJ87467.1 - 0.12 12.4 0.1 0.23 11.6 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1940) Trypsin PF00089.26 CDJ87468.1 - 3.1e-21 76.2 2.2 1.3e-19 70.9 2.2 2.8 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CDJ87468.1 - 0.00029 21.8 0.0 0.0005 21.0 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 CDJ87468.1 - 0.00039 20.1 0.0 0.22 11.1 0.0 2.4 2 0 0 2 2 2 2 Chymotrypsin family Peptidase-S1 AMOP PF03782.17 CDJ87469.1 - 2.3e-45 154.2 6.9 3.7e-45 153.5 6.9 1.4 1 0 0 1 1 1 1 AMOP domain VWD PF00094.25 CDJ87469.1 - 2.4e-14 53.9 0.0 5.8e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type D domain Sushi PF00084.20 CDJ87469.1 - 0.00019 21.9 2.7 0.00019 21.9 2.7 2.6 2 0 0 2 2 2 1 Sushi repeat (SCR repeat) TMEMspv1-c74-12 PF11044.8 CDJ87469.1 - 0.0018 18.2 1.2 0.0034 17.3 1.2 1.4 1 0 0 1 1 1 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein EABR PF12180.8 CDJ87469.1 - 0.042 13.5 0.0 0.092 12.4 0.0 1.4 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 PALP PF00291.25 CDJ87471.1 - 2.1e-21 76.6 0.2 3.2e-18 66.2 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme TerB PF05099.13 CDJ87472.1 - 0.013 15.4 0.0 0.048 13.6 0.0 1.9 1 1 0 2 2 2 0 Tellurite resistance protein TerB Cullin PF00888.22 CDJ87473.1 - 5.2e-167 557.2 3.0 6.8e-167 556.8 3.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CDJ87473.1 - 7.9e-18 64.3 2.1 2.4e-17 62.7 2.1 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain IPPT PF01715.17 CDJ87473.1 - 0.1 12.4 9.7 2.7 7.7 0.1 3.5 4 1 0 4 4 4 0 IPP transferase adh_short PF00106.25 CDJ87474.1 - 2.4e-35 121.8 0.0 3.2e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ87474.1 - 9.8e-22 77.7 0.0 1.6e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ87474.1 - 0.0025 17.8 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Baculo_helicase PF04735.12 CDJ87474.1 - 0.0057 14.3 0.1 0.0079 13.8 0.1 1.1 1 0 0 1 1 1 1 Baculovirus DNA helicase LRR_8 PF13855.6 CDJ87477.1 - 3.3e-20 71.6 0.0 0.00025 20.8 0.0 5.1 2 2 4 6 6 6 5 Leucine rich repeat LRR_5 PF13306.6 CDJ87477.1 - 3.9e-19 68.9 0.1 5e-09 36.2 0.0 2.5 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 CDJ87477.1 - 3e-05 24.3 0.0 0.24 11.9 0.0 4.4 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRRNT PF01462.18 CDJ87477.1 - 0.0029 17.2 4.4 0.0081 15.8 4.4 1.8 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain TPKR_C2 PF16920.5 CDJ87477.1 - 0.013 15.6 0.1 0.058 13.5 0.2 2.1 2 0 0 2 2 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain Hormone_4 PF00220.17 CDJ87477.1 - 0.4 10.7 1.9 10 6.4 0.4 2.8 2 0 0 2 2 2 0 Neurohypophysial hormones, N-terminal Domain LRR_4 PF12799.7 CDJ87478.1 - 2e-09 37.5 11.7 0.00014 22.1 0.8 4.0 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) PP2C PF00481.21 CDJ87478.1 - 2.1e-09 37.4 0.0 3.9e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 CDJ87478.1 - 3.3e-08 33.2 8.3 1.1e-05 25.0 2.7 3.0 2 1 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 CDJ87478.1 - 0.00074 19.4 1.7 3.2 8.1 0.5 3.6 3 0 0 3 3 3 2 Leucine Rich repeat NumbF PF06311.12 CDJ87478.1 - 0.0061 17.1 2.8 1.1 9.9 0.4 3.3 2 0 0 2 2 2 2 NUMB domain ANAPC15 PF15243.6 CDJ87478.1 - 0.31 11.4 1.4 0.5 10.8 0.1 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 LRR_1 PF00560.33 CDJ87478.1 - 0.98 10.2 8.1 4 8.4 0.2 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat UQ_con PF00179.26 CDJ87479.1 - 7.9e-42 142.2 0.2 8.9e-42 142.1 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CDJ87479.1 - 1.5e-05 25.3 0.3 1.7e-05 25.1 0.3 1.3 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 CDJ87479.1 - 5.5e-05 22.9 0.0 6.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CDJ87479.1 - 0.0014 18.5 0.1 0.0024 17.7 0.1 1.5 1 0 0 1 1 1 1 UEV domain DUF1154 PF06631.11 CDJ87479.1 - 0.84 9.7 4.6 1.5 8.9 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) Epimerase PF01370.21 CDJ87480.1 - 4.1e-54 183.6 0.0 6e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CDJ87480.1 - 1.9e-13 50.5 0.4 5.7e-13 49.0 0.0 1.7 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CDJ87480.1 - 2.6e-06 26.8 0.0 5.8e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CDJ87480.1 - 0.0069 15.6 2.2 0.085 12.0 0.1 2.5 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 CDJ87480.1 - 0.29 10.2 1.9 0.92 8.6 0.0 2.2 1 1 1 2 2 2 0 Male sterility protein fn3 PF00041.21 CDJ87481.1 - 1.3e-56 188.8 31.2 2.2e-10 40.7 0.1 10.0 10 0 0 10 10 10 7 Fibronectin type III domain Ig_3 PF13927.6 CDJ87481.1 - 1.5e-18 67.1 3.9 5.1e-05 23.8 0.0 6.2 4 1 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 CDJ87481.1 - 2.1e-16 59.8 2.5 3.1e-05 23.9 0.0 6.1 5 1 0 5 5 5 3 Immunoglobulin I-set domain Pur_ac_phosph_N PF16656.5 CDJ87481.1 - 8.6e-12 45.5 24.0 0.043 14.4 0.6 8.1 10 0 0 10 10 8 5 Purple acid Phosphatase, N-terminal domain Ig_2 PF13895.6 CDJ87481.1 - 3.2e-10 40.2 0.1 0.68 10.3 0.0 5.1 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 CDJ87481.1 - 4.2e-10 39.7 4.9 0.0016 18.6 0.0 5.0 4 2 1 5 5 5 3 Immunoglobulin domain C2-set_2 PF08205.12 CDJ87481.1 - 6.7e-10 38.9 4.8 0.08 13.0 0.1 4.9 4 0 0 4 4 4 4 CD80-like C2-set immunoglobulin domain Interfer-bind PF09294.10 CDJ87481.1 - 2.1e-06 28.0 5.7 0.23 11.8 0.0 6.5 7 0 0 7 7 7 2 Interferon-alpha/beta receptor, fibronectin type III BiPBP_C PF06832.12 CDJ87481.1 - 0.00034 20.6 0.0 0.017 15.2 0.0 3.0 2 0 0 2 2 2 1 Penicillin-Binding Protein C-terminus Family C1-set PF07654.15 CDJ87481.1 - 0.012 16.0 0.2 3.5 8.1 0.0 3.4 3 0 0 3 3 3 0 Immunoglobulin C1-set domain Glyco_hydro_36C PF16874.5 CDJ87481.1 - 0.044 14.3 0.0 13 6.4 0.0 3.8 4 0 0 4 4 4 0 Glycosyl hydrolase family 36 C-terminal domain Big_5 PF13205.6 CDJ87481.1 - 2.7 8.7 17.5 2 9.1 1.7 6.5 6 1 2 8 8 8 0 Bacterial Ig-like domain FTHFS PF01268.19 CDJ87482.1 - 4e-130 434.6 0.2 5.5e-130 434.2 0.2 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase AAA_26 PF13500.6 CDJ87482.1 - 0.1 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Clathrin PF00637.20 CDJ87483.1 - 1.8e-09 37.6 31.3 0.0017 18.3 0.1 9.1 7 1 0 8 8 8 4 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 CDJ87483.1 - 2.3e-06 27.8 0.0 0.53 10.6 0.1 4.9 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 CDJ87483.1 - 0.00067 19.6 39.2 0.59 10.4 0.1 12.9 12 2 2 14 14 14 2 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 CDJ87483.1 - 0.0014 17.7 0.1 0.0014 17.7 0.1 5.4 7 0 0 7 7 7 1 Coatomer WD associated region TPR_1 PF00515.28 CDJ87483.1 - 0.0017 18.1 30.6 0.038 13.8 0.1 10.5 10 1 1 11 11 11 2 Tetratricopeptide repeat DUF3592 PF12158.8 CDJ87483.1 - 0.034 14.2 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) TPR_8 PF13181.6 CDJ87483.1 - 0.057 13.7 23.7 0.77 10.1 0.1 7.7 7 0 0 7 7 7 0 Tetratricopeptide repeat WD40 PF00400.32 CDJ87483.1 - 0.82 10.6 7.9 8.4 7.5 0.0 5.1 6 0 0 6 6 6 0 WD domain, G-beta repeat Mad3_BUB1_I PF08311.12 CDJ87483.1 - 0.96 9.4 14.3 5.2 7.1 0.3 6.0 6 1 0 6 6 6 0 Mad3/BUB1 homology region 1 CENP-T_C PF15511.6 CDJ87484.1 - 0.022 14.9 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Tis11B_N PF04553.12 CDJ87484.1 - 0.082 13.5 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Tis11B like protein, N terminus DUF2534 PF10749.9 CDJ87484.1 - 0.24 11.6 4.0 4.1 7.6 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2534) Col_cuticle_N PF01484.17 CDJ87484.1 - 1.1 9.3 5.3 1.2 9.3 0.0 3.1 2 1 1 3 3 3 0 Nematode cuticle collagen N-terminal domain SDF PF00375.18 CDJ87487.1 - 1.3e-118 396.4 28.7 1.5e-118 396.2 28.7 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF4212 PF13937.6 CDJ87487.1 - 5.2 7.5 6.6 24 5.4 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) DUF2318 PF10080.9 CDJ87488.1 - 0.036 14.2 0.0 0.045 13.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) RVT_1 PF00078.27 CDJ87489.1 - 1.1e-16 61.1 0.0 1.6e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Recep_L_domain PF01030.24 CDJ87490.1 - 1.2e-16 60.8 0.9 8.8e-09 35.5 0.2 3.7 3 0 0 3 3 3 3 Receptor L domain DUF4834 PF16118.5 CDJ87490.1 - 0.0069 17.3 0.5 0.0069 17.3 0.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) Rax2 PF12768.7 CDJ87490.1 - 0.015 14.8 0.0 0.03 13.8 0.0 1.6 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Myc_target_1 PF15179.6 CDJ87490.1 - 0.03 14.2 0.2 0.03 14.2 0.2 1.9 2 0 0 2 2 2 0 Myc target protein 1 EphA2_TM PF14575.6 CDJ87490.1 - 0.11 13.4 0.1 0.26 12.2 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF948 PF06103.11 CDJ87490.1 - 0.81 10.0 3.9 0.66 10.3 0.1 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) FAM176 PF14851.6 CDJ87490.1 - 0.92 9.2 3.9 1.3 8.7 0.1 2.2 2 0 0 2 2 2 0 FAM176 family Tmemb_9 PF05434.11 CDJ87490.1 - 4.6 7.1 7.1 0.45 10.4 0.6 2.4 3 0 0 3 3 3 0 TMEM9 TMEM154 PF15102.6 CDJ87490.1 - 7.4 6.5 11.2 18 5.2 10.3 2.1 1 1 1 2 2 2 0 TMEM154 protein family UDPGT PF00201.18 CDJ87492.1 - 2.7e-05 23.2 0.0 2.8e-05 23.1 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 CDJ87494.1 - 5.6e-25 88.1 0.0 6.3e-25 87.9 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ87494.1 - 2.4e-13 50.4 0.0 2.9e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 CDJ87494.1 - 0.0016 17.8 0.0 0.0019 17.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 UDPGT PF00201.18 CDJ87495.1 - 0.037 12.8 0.0 0.041 12.7 0.0 1.0 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase YmgD PF16456.5 CDJ87495.1 - 0.043 13.9 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 YmgD protein HCMV_UL139 PF12507.8 CDJ87496.1 - 0.0052 17.2 2.1 0.0079 16.6 2.1 1.4 1 0 0 1 1 1 1 Human Cytomegalovirus UL139 protein DUF932 PF06067.11 CDJ87496.1 - 0.086 12.6 3.3 0.12 12.2 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF932) THOC7 PF05615.13 CDJ87496.1 - 0.63 10.3 15.3 0.4 11.0 12.3 2.0 1 1 1 2 2 2 0 Tho complex subunit 7 DUF4407 PF14362.6 CDJ87496.1 - 6.4 6.0 12.4 8.9 5.6 12.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-H PF05837.12 CDJ87496.1 - 7.1 7.1 17.7 1 9.8 11.0 2.5 2 1 1 3 3 3 0 Centromere protein H (CENP-H) UDPGT PF00201.18 CDJ87497.1 - 5.1e-08 32.2 0.0 6e-08 31.9 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase SPASM PF13186.6 CDJ87497.1 - 0.1 13.2 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 Iron-sulfur cluster-binding domain RVT_1 PF00078.27 CDJ87499.1 - 3.8e-09 36.4 0.0 6.2e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-binding PF00249.31 CDJ87500.1 - 3.5e-30 103.9 2.7 1.8e-12 47.3 0.0 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ87500.1 - 2.7e-21 75.6 0.0 3.4e-10 40.0 0.0 3.0 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 CDJ87500.1 - 3.8e-06 26.9 0.1 0.081 13.0 0.0 2.1 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 CDJ87500.1 - 0.00098 19.3 2.6 0.035 14.3 1.1 2.1 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 CDJ87500.1 - 0.0099 16.0 0.7 0.21 11.8 0.3 2.5 1 1 1 2 2 2 1 Rap1 Myb domain Rap1_C PF11626.8 CDJ87500.1 - 0.017 15.2 0.2 0.6 10.2 0.2 2.1 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain fn1 PF00039.18 CDJ87500.1 - 0.23 11.7 1.9 0.26 11.5 0.3 1.9 2 0 0 2 2 2 0 Fibronectin type I domain Lge1 PF11488.8 CDJ87501.1 - 0.05 13.8 0.2 0.05 13.8 0.2 2.6 3 0 0 3 3 3 0 Transcriptional regulatory protein LGE1 AT_hook PF02178.19 CDJ87501.1 - 5.9 7.1 17.1 0.1 12.6 5.3 2.9 2 0 0 2 2 2 0 AT hook motif IMS PF00817.20 CDJ87502.1 - 2.6e-38 131.4 0.0 5.8e-38 130.2 0.0 1.6 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 CDJ87502.1 - 1e-13 52.0 0.3 2.1e-13 51.0 0.3 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 CDJ87502.1 - 5.3e-08 32.7 0.0 1.3e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Ets PF00178.22 CDJ87503.1 - 7.8e-05 23.1 0.2 0.00017 22.0 0.2 1.5 1 0 0 1 1 1 1 Ets-domain ExsD PF16806.5 CDJ87503.1 - 0.19 11.6 0.4 11 5.9 0.0 2.1 2 0 0 2 2 2 0 Antiactivator protein ExsD GYF PF02213.16 CDJ87504.1 - 0.0051 16.5 0.1 0.011 15.4 0.1 1.7 1 0 0 1 1 1 1 GYF domain zf-C2H2_2 PF12756.7 CDJ87504.1 - 0.0072 16.6 6.4 0.036 14.4 0.4 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.12 CDJ87504.1 - 0.36 11.0 4.4 3.3 7.9 0.5 2.5 2 1 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-met PF12874.7 CDJ87504.1 - 0.36 11.3 4.3 2.1 8.8 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Glyco_hydro_30 PF02055.16 CDJ87505.1 - 2.3e-88 296.5 0.6 2.7e-88 296.3 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 CDJ87505.1 - 0.00026 21.2 2.9 0.00049 20.2 2.9 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain HCV_NS5a_1b PF08301.13 CDJ87505.1 - 0.097 13.2 0.0 0.43 11.2 0.0 2.0 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a domain 1b ADH_N_assoc PF13823.6 CDJ87505.1 - 0.5 10.4 0.1 0.5 10.4 0.1 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated zf-C2H2_2 PF12756.7 CDJ87506.1 - 0.0048 17.2 6.5 0.027 14.8 0.4 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CDJ87506.1 - 0.2 12.1 4.3 1.7 9.2 0.4 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type AKAP95 PF04988.12 CDJ87506.1 - 0.29 11.4 4.9 2.6 8.3 0.5 2.6 2 1 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Glyco_hydro_30 PF02055.16 CDJ87507.1 - 2.3e-88 296.5 0.6 2.7e-88 296.3 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 CDJ87507.1 - 0.00026 21.2 2.9 0.00049 20.2 2.9 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain HCV_NS5a_1b PF08301.13 CDJ87507.1 - 0.097 13.2 0.0 0.43 11.2 0.0 2.0 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a domain 1b ADH_N_assoc PF13823.6 CDJ87507.1 - 0.5 10.4 0.1 0.5 10.4 0.1 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated DUF3130 PF11328.8 CDJ87510.1 - 0.044 14.0 0.1 0.13 12.6 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3130 Nup54 PF13874.6 CDJ87510.1 - 0.13 12.4 0.2 0.13 12.4 0.2 2.4 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 IZUMO PF15005.6 CDJ87510.1 - 0.47 11.0 5.1 0.48 10.9 0.7 2.2 2 1 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated bZIP_1 PF00170.21 CDJ87510.1 - 1.5 9.0 7.3 8.7 6.5 0.3 3.0 3 0 0 3 3 3 0 bZIP transcription factor HIP1_clath_bdg PF16515.5 CDJ87510.1 - 2.6 8.7 9.1 1.9 9.1 0.7 2.5 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Actin PF00022.19 CDJ87511.1 - 6.2e-121 403.8 0.0 2.4e-120 401.9 0.0 1.7 1 1 0 1 1 1 1 Actin adh_short_C2 PF13561.6 CDJ87512.1 - 5e-53 180.1 0.1 6.4e-53 179.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDJ87512.1 - 2.4e-45 154.4 0.2 3.1e-45 154.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase THF_DHG_CYH_C PF02882.19 CDJ87512.1 - 2e-05 23.9 0.4 5.6e-05 22.5 0.1 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain KR PF08659.10 CDJ87512.1 - 0.0046 16.9 0.0 0.0065 16.4 0.0 1.2 1 0 0 1 1 1 1 KR domain ApbA PF02558.16 CDJ87512.1 - 0.024 14.3 0.1 0.22 11.1 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Epimerase PF01370.21 CDJ87512.1 - 0.044 13.2 0.1 0.1 12.1 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family KNOX1 PF03790.13 CDJ87512.1 - 0.09 12.5 0.4 0.63 9.8 0.1 2.2 2 0 0 2 2 2 0 KNOX1 domain adh_short_C2 PF13561.6 CDJ87513.1 - 6.8e-53 179.6 0.1 8.9e-53 179.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDJ87513.1 - 1.8e-45 154.8 0.6 2.3e-45 154.4 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase THF_DHG_CYH_C PF02882.19 CDJ87513.1 - 2.5e-05 23.7 0.1 6.7e-05 22.3 0.1 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain KR PF08659.10 CDJ87513.1 - 0.0059 16.5 0.0 0.0084 16.0 0.0 1.2 1 0 0 1 1 1 1 KR domain KNOX1 PF03790.13 CDJ87513.1 - 0.18 11.5 0.7 2.4 8.0 0.1 2.4 2 0 0 2 2 2 0 KNOX1 domain adh_short_C2 PF13561.6 CDJ87514.1 - 1.2e-50 172.3 0.1 1.4e-50 172.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDJ87514.1 - 5.5e-44 150.0 0.4 7.1e-44 149.6 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDJ87514.1 - 0.0004 20.3 0.1 0.00062 19.7 0.1 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 CDJ87514.1 - 0.00057 19.2 0.3 0.0019 17.5 0.1 1.9 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 CDJ87514.1 - 0.023 14.2 0.3 0.15 11.5 0.3 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ApbA PF02558.16 CDJ87514.1 - 0.066 12.9 0.1 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA adh_short_C2 PF13561.6 CDJ87515.1 - 1.8e-52 178.2 0.0 2.3e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDJ87515.1 - 1.8e-47 161.3 0.2 2.4e-47 160.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDJ87515.1 - 0.00021 21.3 0.0 0.00027 20.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDJ87515.1 - 0.0005 19.6 0.0 0.001 18.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 CDJ87515.1 - 0.00092 18.6 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 CDJ87515.1 - 0.014 14.8 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase ApbA PF02558.16 CDJ87515.1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Patched PF02460.18 CDJ87516.1 - 1.2e-72 245.3 20.6 2.2e-72 244.4 20.6 1.3 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 CDJ87516.1 - 2.8e-14 53.2 5.8 2.8e-14 53.2 5.8 3.1 2 1 1 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation DUF4516 PF14990.6 CDJ87516.1 - 0.12 12.1 1.5 0.32 10.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) Nucleoside_tran PF01733.18 CDJ87518.1 - 5.4e-56 190.2 24.5 2e-55 188.4 19.0 2.5 2 1 0 2 2 2 1 Nucleoside transporter TCTP PF00838.17 CDJ87518.1 - 0.055 13.8 0.4 0.098 13.0 0.4 1.3 1 0 0 1 1 1 0 Translationally controlled tumour protein Tmemb_55A PF09788.9 CDJ87518.1 - 3.1 6.8 5.0 5 6.1 3.8 2.0 2 0 0 2 2 2 0 Transmembrane protein 55A KH_1 PF00013.29 CDJ87521.1 - 3.1e-66 219.1 15.5 6.1e-16 58.0 0.3 4.3 4 0 0 4 4 4 4 KH domain DUF1897 PF09005.10 CDJ87521.1 - 3.1e-20 71.4 2.9 7e-20 70.2 2.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1897) KH_2 PF07650.17 CDJ87521.1 - 5.3e-19 67.8 13.4 0.00026 20.7 1.0 4.4 2 1 1 4 4 4 4 KH domain KH_4 PF13083.6 CDJ87521.1 - 2.6e-14 52.9 3.7 0.0097 15.8 0.0 4.4 4 0 0 4 4 4 4 KH domain KH_5 PF13184.6 CDJ87521.1 - 0.0012 18.9 4.0 7.3 6.8 0.1 4.2 4 0 0 4 4 4 2 NusA-like KH domain Peptidase_S24 PF00717.23 CDJ87521.1 - 0.037 14.0 0.0 6.5 6.8 0.0 3.2 3 0 0 3 3 3 0 Peptidase S24-like DUF2014 PF09427.10 CDJ87522.1 - 0.17 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) Neur_chan_LBD PF02931.23 CDJ87523.1 - 2.4e-45 154.6 0.2 3.1e-45 154.3 0.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ87523.1 - 6.6e-14 52.5 7.8 1.8e-13 51.1 4.1 2.3 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Mo25 PF08569.11 CDJ87524.1 - 2e-140 467.8 8.7 2.2e-140 467.7 8.7 1.0 1 0 0 1 1 1 1 Mo25-like MOR2-PAG1_C PF14225.6 CDJ87524.1 - 0.12 12.3 1.5 1.5 8.6 0.9 2.7 2 1 0 2 2 2 0 Cell morphogenesis C-terminal OATP PF03137.20 CDJ87525.1 - 4.4e-142 474.2 13.2 5.2e-142 473.9 13.2 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 CDJ87525.1 - 1.2e-11 44.2 19.6 1.2e-11 44.2 19.6 3.4 3 1 1 4 4 4 2 Major Facilitator Superfamily Kazal_2 PF07648.15 CDJ87525.1 - 0.01 15.9 7.5 0.023 14.8 7.5 1.6 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Complex1_51K PF01512.17 CDJ87526.1 - 1.4e-48 164.6 0.0 2.3e-48 163.9 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 CDJ87526.1 - 1.6e-27 95.4 1.0 3.1e-27 94.5 0.2 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 CDJ87526.1 - 6.4e-08 32.4 0.0 1.3e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 SLBB domain tRNA-synt_1 PF00133.22 CDJ87527.1 - 5.9e-20 71.1 0.2 4.1e-19 68.3 0.0 1.8 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 CDJ87527.1 - 1.3e-07 31.3 0.0 1.6e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1 PF00133.22 CDJ87528.1 - 5.4e-88 295.8 0.1 6.7e-88 295.5 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDJ87528.1 - 8.3e-39 133.0 0.0 2e-38 131.7 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CDJ87528.1 - 6.9e-05 21.8 0.4 0.1 11.3 0.3 3.0 1 1 1 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CDJ87528.1 - 0.0026 17.2 0.0 0.0086 15.4 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain RRM_1 PF00076.22 CDJ87529.1 - 4.3e-15 55.3 0.0 7.4e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Collagen PF01391.18 CDJ87530.1 - 3.3e-25 87.6 119.7 1.4e-10 40.8 38.0 4.1 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ87530.1 - 9.2e-21 73.7 0.7 1.3e-20 73.2 0.7 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain PAX PF00292.18 CDJ87531.1 - 1.4e-16 60.6 0.1 2.2e-16 59.9 0.1 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 CDJ87531.1 - 1.2e-08 34.4 0.0 1.9e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 CDJ87531.1 - 1.9e-05 24.4 0.0 3.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 CDJ87531.1 - 0.00051 20.0 0.0 0.00086 19.3 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 CDJ87531.1 - 0.014 15.5 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Terminase_5 PF06056.12 CDJ87531.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Choline_transpo PF04515.12 CDJ87532.1 - 8.1e-100 334.2 27.9 8.1e-100 334.2 27.9 2.6 2 1 1 3 3 3 1 Plasma-membrane choline transporter SieB PF14163.6 CDJ87532.1 - 10 5.6 13.4 10 5.6 0.5 3.7 3 1 0 3 3 3 0 Super-infection exclusion protein B Melibiase_2 PF16499.5 CDJ87533.1 - 7.3e-69 232.1 7.0 1e-51 175.8 1.4 2.1 1 1 1 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 CDJ87533.1 - 1e-12 47.9 0.0 2.7e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase_2_C PF17450.2 CDJ87533.1 - 2.9e-07 30.6 0.0 6e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase PF02065.18 CDJ87533.1 - 0.0049 15.9 0.0 0.0076 15.2 0.0 1.2 1 0 0 1 1 1 1 Melibiase Toprim_3 PF13362.6 CDJ87533.1 - 0.0062 16.9 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Gelsolin PF00626.22 CDJ87535.1 - 2.6e-11 43.3 0.0 3.9e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Gelsolin repeat PA14 PF07691.12 CDJ87535.1 - 0.041 13.7 0.2 0.072 12.9 0.2 1.3 1 1 0 1 1 1 0 PA14 domain Syntaxin PF00804.25 CDJ87536.1 - 6.4e-25 88.0 4.6 1.4e-24 86.9 4.6 1.6 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 CDJ87536.1 - 1.3e-16 60.3 2.2 2.6e-16 59.3 2.2 1.5 1 0 0 1 1 1 1 SNARE domain Synaptobrevin PF00957.21 CDJ87536.1 - 0.00015 21.5 0.8 0.00015 21.5 0.8 2.6 3 0 0 3 3 3 1 Synaptobrevin DUF5345 PF17280.2 CDJ87536.1 - 0.0091 15.9 0.6 0.031 14.2 0.2 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5345) THP2 PF09432.10 CDJ87536.1 - 0.014 15.5 4.0 0.42 10.7 0.0 3.4 1 1 2 4 4 4 0 Tho complex subunit THP2 ETRAMP PF09716.10 CDJ87536.1 - 0.015 15.4 0.3 0.023 14.8 0.3 1.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) EVI2A PF05399.11 CDJ87536.1 - 0.047 13.3 0.3 0.1 12.2 0.3 1.5 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Orf78 PF06024.12 CDJ87536.1 - 0.17 12.2 1.5 0.21 11.9 0.2 1.8 2 0 0 2 2 2 0 Orf78 (ac78) Sigma_reg_N PF13800.6 CDJ87536.1 - 0.21 11.9 3.3 0.45 10.8 3.3 1.6 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF3347 PF11827.8 CDJ87536.1 - 1.8 8.7 7.3 0.25 11.5 0.9 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3347) DUF4635 PF15466.6 CDJ87536.1 - 2.4 7.7 8.0 1.8 8.1 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4635) Arm PF00514.23 CDJ87537.1 - 7.7e-80 260.8 19.2 6.1e-13 48.3 0.2 9.1 8 1 1 9 9 9 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 CDJ87537.1 - 4.9e-24 83.6 5.0 1.2e-20 72.8 3.7 2.6 3 0 0 3 3 3 2 Atypical Arm repeat HEAT_EZ PF13513.6 CDJ87537.1 - 1e-19 70.6 8.5 2.5e-06 27.8 0.2 6.8 5 2 3 8 8 8 4 HEAT-like repeat HEAT_2 PF13646.6 CDJ87537.1 - 8e-18 64.6 0.2 0.0064 16.9 0.0 6.0 2 2 4 6 6 6 6 HEAT repeats HEAT PF02985.22 CDJ87537.1 - 4.6e-16 57.6 1.3 0.0027 17.8 0.0 6.2 5 0 0 5 5 5 3 HEAT repeat IBB PF01749.20 CDJ87537.1 - 3.5e-15 56.2 0.1 1.9e-13 50.6 0.1 2.8 2 0 0 2 2 2 1 Importin beta binding domain V-ATPase_H_C PF11698.8 CDJ87537.1 - 4.3e-06 26.8 0.7 0.54 10.4 0.0 4.2 4 1 1 5 5 5 3 V-ATPase subunit H Cnd1 PF12717.7 CDJ87537.1 - 0.00018 21.6 0.6 2.5 8.1 0.0 3.9 2 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Arm_2 PF04826.13 CDJ87537.1 - 0.00051 19.6 1.9 0.56 9.6 0.2 4.4 3 1 0 3 3 3 1 Armadillo-like NopRA1 PF16201.5 CDJ87537.1 - 0.012 15.2 0.0 1.6 8.3 0.0 3.5 3 1 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 Capsid-VNN PF11729.8 CDJ87537.1 - 0.048 12.7 0.0 0.18 10.8 0.0 2.0 2 0 0 2 2 2 0 nodavirus capsid protein DUF3361 PF11841.8 CDJ87537.1 - 0.066 13.2 0.4 0.23 11.4 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3361) CD20 PF04103.15 CDJ87538.1 - 1.7e-24 86.6 9.4 2.5e-24 86.1 9.4 1.2 1 0 0 1 1 1 1 CD20-like family LexA_DNA_bind PF01726.16 CDJ87538.1 - 0.11 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 LexA DNA binding domain Tetraspanin PF00335.20 CDJ87538.1 - 2.7 7.6 10.5 5.4 6.7 9.1 2.0 1 1 1 2 2 2 0 Tetraspanin family XendoU PF09412.10 CDJ87539.1 - 3.4e-50 170.7 0.6 3.8e-50 170.6 0.6 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU TetR_C_13 PF16925.5 CDJ87539.1 - 0.016 15.1 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain EndoU_bacteria PF14436.6 CDJ87539.1 - 0.061 13.7 0.2 0.14 12.5 0.1 1.7 2 0 0 2 2 2 0 Bacterial EndoU nuclease Ion_trans PF00520.31 CDJ87540.1 - 0.043 13.0 1.0 0.05 12.8 1.0 1.1 1 0 0 1 1 1 0 Ion transport protein XendoU PF09412.10 CDJ87541.1 - 1.7e-63 214.3 1.9 1.9e-63 214.1 1.9 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU fn3 PF00041.21 CDJ87544.1 - 1.5e-23 82.9 0.1 3.2e-08 33.8 0.0 6.0 6 0 0 6 6 6 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CDJ87544.1 - 6.2e-08 33.1 0.1 0.098 13.2 0.0 4.6 5 1 0 5 5 5 3 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 CDJ87544.1 - 7.1e-06 26.3 0.0 0.0095 16.2 0.1 2.9 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III FAA_hydrolase PF01557.18 CDJ87545.1 - 2.1e-56 191.1 0.0 2.7e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 CDJ87545.1 - 5.5e-34 116.6 0.1 9.5e-34 115.8 0.1 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal DUF4145 PF13643.6 CDJ87545.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) CDC37_M PF08565.11 CDJ87546.1 - 1.8e-19 69.8 0.3 5.6e-19 68.2 0.3 1.8 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_N PF03234.14 CDJ87546.1 - 3e-14 54.1 15.9 3e-14 54.1 15.9 2.2 2 1 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_C PF08564.10 CDJ87546.1 - 1.4e-09 38.0 0.1 1.4e-09 38.0 0.1 3.3 2 2 1 3 3 3 1 Cdc37 C terminal domain DUF4065 PF13274.6 CDJ87546.1 - 1.2 10.1 9.7 19 6.2 6.9 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) HSP70 PF00012.20 CDJ87546.1 - 3.1 5.9 10.8 6.4 4.8 10.8 1.4 1 0 0 1 1 1 0 Hsp70 protein CemA PF03040.14 CDJ87546.1 - 7.4 6.4 9.7 13 5.6 0.3 2.4 2 0 0 2 2 2 0 CemA family ERG2_Sigma1R PF04622.12 CDJ87547.1 - 8.3e-23 80.8 0.0 9.8e-23 80.6 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Patatin PF01734.22 CDJ87548.1 - 3e-14 53.7 0.3 1e-13 52.0 0.3 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase DUF4551 PF15087.6 CDJ87548.1 - 3.4 6.4 11.4 5.4 5.7 11.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Collagen PF01391.18 CDJ87549.1 - 3.3e-26 90.8 92.6 7.9e-11 41.6 33.0 3.7 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ87549.1 - 3.5e-10 39.8 0.1 4.9e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Lectin_C PF00059.21 CDJ87550.1 - 3.4e-15 56.7 0.3 1.4e-07 32.2 0.1 3.3 2 1 0 2 2 2 2 Lectin C-type domain Piwi PF02171.17 CDJ87551.1 - 4.4e-117 390.6 0.0 7.1e-117 390.0 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 CDJ87551.1 - 1.2e-33 115.2 1.3 1.9e-33 114.6 0.3 2.0 2 0 0 2 2 2 1 Mid domain of argonaute ArgoN PF16486.5 CDJ87551.1 - 3e-28 99.1 0.0 7.2e-28 97.9 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 CDJ87551.1 - 1.1e-26 93.3 0.4 2.1e-26 92.4 0.4 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 CDJ87551.1 - 2.8e-22 78.1 0.0 5.9e-22 77.1 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 CDJ87551.1 - 1.8e-12 47.4 0.0 4e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain MFS_1 PF07690.16 CDJ87553.1 - 2.4e-35 122.1 16.8 2.4e-35 122.1 16.8 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 CDJ87553.1 - 0.012 14.2 18.9 0.0079 14.8 15.9 2.3 2 1 0 2 2 2 0 MFS/sugar transport protein PMT_4TMC PF16192.5 CDJ87553.1 - 1.3 8.6 10.9 0.048 13.2 4.0 2.0 2 1 0 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase TMEM144 PF07857.12 CDJ87554.1 - 1e-114 383.0 17.8 1.2e-114 382.8 17.8 1.0 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 CDJ87554.1 - 7e-08 32.1 17.7 4.5e-05 22.9 2.9 2.5 2 1 0 2 2 2 2 Sugar transport protein DUF3671 PF12420.8 CDJ87554.1 - 0.004 17.2 2.8 0.004 17.2 2.8 2.7 3 1 1 4 4 4 1 Protein of unknown function COX2_TM PF02790.15 CDJ87554.1 - 0.016 15.4 7.1 0.021 15.0 0.1 3.4 3 1 1 4 4 4 0 Cytochrome C oxidase subunit II, transmembrane domain CcmH PF03918.14 CDJ87554.1 - 0.11 11.8 0.0 0.45 9.8 0.0 2.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Gram_pos_anchor PF00746.21 CDJ87554.1 - 0.92 9.5 2.8 52 3.9 1.5 3.4 3 0 0 3 3 3 0 LPXTG cell wall anchor motif 1-cysPrx_C PF10417.9 CDJ87555.1 - 3.2 7.7 0.0 3.2 7.7 0.0 3.4 4 0 0 4 4 4 0 C-terminal domain of 1-Cys peroxiredoxin Zip PF02535.22 CDJ87556.1 - 1.1 8.4 3.3 1.3 8.2 3.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Innexin PF00876.18 CDJ87557.1 - 6.1e-87 292.2 5.5 7.3e-87 291.9 5.5 1.0 1 0 0 1 1 1 1 Innexin Ephrin PF00812.17 CDJ87558.1 - 1.7e-17 63.7 0.1 8.8e-17 61.4 0.1 2.0 1 1 0 1 1 1 1 Ephrin D5_N PF08706.11 CDJ87558.1 - 0.11 12.7 0.1 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 D5 N terminal like Glyoxalase_2 PF12681.7 CDJ87559.1 - 0.043 13.7 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain UDPGT PF00201.18 CDJ87561.1 - 1.9e-77 261.2 0.5 2.4e-77 260.9 0.5 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ87561.1 - 3.1e-09 37.0 0.0 5.5e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.6 CDJ87561.1 - 0.00013 22.0 0.0 0.00051 20.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase Family 4 DUF1980 PF09323.10 CDJ87561.1 - 0.02 14.8 0.5 0.15 11.9 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) Glyco_trans_4_4 PF13579.6 CDJ87561.1 - 0.033 14.6 0.0 0.059 13.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain CHCH PF06747.13 CDJ87562.1 - 0.00035 20.6 0.0 0.00091 19.3 0.0 1.8 1 1 0 1 1 1 1 CHCH domain CHCH PF06747.13 CDJ87563.1 - 0.0011 19.1 1.2 0.0027 17.8 1.2 1.7 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 CDJ87563.1 - 0.052 13.6 4.4 0.057 13.4 1.8 2.2 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Actin PF00022.19 CDJ87564.1 - 7.5e-129 429.9 0.0 8.4e-129 429.7 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CDJ87564.1 - 0.015 14.2 0.1 1.8 7.3 0.0 2.6 2 1 0 2 2 2 0 MreB/Mbl protein MFS_1 PF07690.16 CDJ87565.1 - 1.1e-29 103.5 32.1 3.8e-18 65.5 3.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CDJ87565.1 - 4.5e-12 45.3 24.6 1.3e-10 40.4 17.4 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein FA_desaturase PF00487.24 CDJ87565.1 - 0.36 10.6 4.3 0.71 9.7 4.3 1.7 1 0 0 1 1 1 0 Fatty acid desaturase MFS_1 PF07690.16 CDJ87566.1 - 1.2e-45 156.0 24.9 5e-36 124.4 3.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CDJ87566.1 - 1.3e-05 23.7 0.1 0.0002 19.8 0.0 2.4 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Sulfotransfer_2 PF03567.14 CDJ87567.1 - 5.8e-13 49.3 3.8 7.5e-13 49.0 3.8 1.1 1 0 0 1 1 1 1 Sulfotransferase family DUF3007 PF11460.8 CDJ87567.1 - 0.0027 17.9 0.0 1.2 9.5 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3007) CIDR1_gamma PF18562.1 CDJ87567.1 - 0.0033 17.5 0.2 0.014 15.5 0.0 2.1 2 0 0 2 2 2 1 Cysteine-Rich Interdomain Region 1 gamma Chordopox_G3 PF06129.12 CDJ87568.1 - 0.009 16.7 0.0 0.019 15.6 0.0 1.5 1 0 0 1 1 1 1 Chordopoxvirus G3 protein LRR_8 PF13855.6 CDJ87569.1 - 1.1e-23 82.7 10.9 5.3e-11 42.1 0.4 4.5 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CDJ87569.1 - 2.5e-12 46.8 12.8 0.00021 21.6 0.0 5.4 3 1 4 7 7 7 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CDJ87569.1 - 2.8e-09 37.0 0.0 3.3e-08 33.5 0.0 2.1 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 CDJ87569.1 - 2.4e-07 30.4 12.3 0.85 10.4 0.0 7.7 6 2 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 CDJ87569.1 - 3.5 7.9 0.0 3.5 7.9 0.0 6.3 8 0 0 8 8 8 0 Leucine Rich repeat NUC153 PF08159.12 CDJ87570.1 - 2.8e-05 23.9 1.9 6.8e-05 22.6 1.9 1.7 1 0 0 1 1 1 1 NUC153 domain ANAPC4_WD40 PF12894.7 CDJ87570.1 - 0.028 14.7 0.0 0.28 11.5 0.0 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ87570.1 - 0.16 12.9 0.2 3.3 8.7 0.0 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat zf-C4H2 PF10146.9 CDJ87571.1 - 1.8e-48 165.6 14.3 2.3e-48 165.3 14.3 1.1 1 0 0 1 1 1 1 Zinc finger-containing protein zf-C3HC4_3 PF13920.6 CDJ87571.1 - 0.0081 16.0 4.3 0.014 15.3 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 CDJ87571.1 - 0.028 14.4 1.6 0.051 13.6 1.6 1.4 1 0 0 1 1 1 0 Double zinc ribbon Prok-RING_4 PF14447.6 CDJ87571.1 - 0.052 13.4 4.0 0.097 12.5 4.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CDJ87571.1 - 0.072 12.9 3.1 0.14 12.0 3.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 CDJ87571.1 - 0.21 11.5 4.7 0.38 10.6 4.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FliD_C PF07195.12 CDJ87571.1 - 0.25 10.7 3.1 0.32 10.4 3.1 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus FapA PF03961.13 CDJ87571.1 - 1.1 7.7 5.3 1.5 7.4 5.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Baculo_IE-1 PF05290.11 CDJ87571.1 - 1.2 9.1 5.6 2.2 8.2 1.5 2.2 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) UPF0242 PF06785.11 CDJ87571.1 - 2 8.5 12.1 2.8 8.0 12.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus zf-C4H2 PF10146.9 CDJ87572.1 - 2e-37 129.6 22.8 4.6e-37 128.4 22.8 1.5 1 1 0 1 1 1 1 Zinc finger-containing protein DUF1635 PF07795.11 CDJ87572.1 - 1.5e-05 25.0 3.4 2e-05 24.6 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) LUC7 PF03194.15 CDJ87572.1 - 9.2e-05 22.2 1.5 0.00013 21.8 1.5 1.1 1 0 0 1 1 1 1 LUC7 N_terminus DHR10 PF18595.1 CDJ87572.1 - 0.0019 18.2 9.8 0.003 17.6 9.8 1.2 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain OmpH PF03938.14 CDJ87572.1 - 0.0031 17.8 3.0 0.0048 17.2 3.0 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DZR PF12773.7 CDJ87572.1 - 0.0038 17.2 1.4 0.0038 17.2 1.4 1.8 2 0 0 2 2 2 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 CDJ87572.1 - 0.0041 16.8 2.3 0.0083 15.8 2.3 1.5 1 0 0 1 1 1 1 zinc-ribbon domain TPR_MLP1_2 PF07926.12 CDJ87572.1 - 0.005 16.9 5.9 0.0076 16.3 5.9 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 CDJ87572.1 - 0.0053 16.3 5.1 0.0068 15.9 5.1 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 zf-C3HC4_3 PF13920.6 CDJ87572.1 - 0.0059 16.4 3.5 0.0059 16.4 3.5 1.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SCP-1 PF05483.12 CDJ87572.1 - 0.0065 14.5 4.1 0.0078 14.3 4.1 1.1 1 0 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) zf-ribbon_3 PF13248.6 CDJ87572.1 - 0.0077 15.6 2.8 0.016 14.6 2.8 1.5 1 0 0 1 1 1 1 zinc-ribbon domain FliT PF05400.13 CDJ87572.1 - 0.0082 16.9 11.1 0.018 15.8 11.1 1.6 1 0 0 1 1 1 1 Flagellar protein FliT Tup_N PF08581.10 CDJ87572.1 - 0.011 16.1 7.1 0.018 15.3 7.1 1.3 1 0 0 1 1 1 0 Tup N-terminal DUF3584 PF12128.8 CDJ87572.1 - 0.014 12.9 3.8 0.017 12.7 3.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF724 PF05266.14 CDJ87572.1 - 0.018 14.9 3.3 0.024 14.5 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Laminin_II PF06009.12 CDJ87572.1 - 0.018 15.0 2.4 0.028 14.4 2.4 1.3 1 0 0 1 1 1 0 Laminin Domain II zf_C2HC_14 PF18574.1 CDJ87572.1 - 0.019 14.7 1.1 0.019 14.7 1.1 2.4 3 0 0 3 3 2 0 C2HC Zing finger domain FapA PF03961.13 CDJ87572.1 - 0.034 12.8 1.8 0.042 12.5 1.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A EPSP_synthase PF00275.20 CDJ87572.1 - 0.068 11.8 0.6 0.092 11.4 0.6 1.1 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Syntaxin_2 PF14523.6 CDJ87572.1 - 0.084 13.2 5.3 0.13 12.7 3.0 2.0 1 1 1 2 2 2 0 Syntaxin-like protein HAUS-augmin3 PF14932.6 CDJ87572.1 - 0.086 12.4 4.7 0.11 12.0 4.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 PI3K_P85_iSH2 PF16454.5 CDJ87572.1 - 0.23 11.1 8.9 0.52 9.9 8.2 1.7 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain V_ATPase_I PF01496.19 CDJ87572.1 - 0.23 9.3 1.3 0.27 9.1 1.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 CDJ87572.1 - 0.23 10.7 2.0 0.3 10.3 2.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF1515 PF07439.11 CDJ87572.1 - 0.24 11.4 4.4 0.42 10.7 3.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) Rho_Binding PF08912.11 CDJ87572.1 - 0.27 12.1 7.9 2.5 9.0 7.4 2.6 1 1 2 3 3 3 0 Rho Binding GrpE PF01025.19 CDJ87572.1 - 0.39 10.3 5.0 0.58 9.8 5.0 1.3 1 0 0 1 1 1 0 GrpE Prefoldin PF02996.17 CDJ87572.1 - 0.58 10.1 5.1 0.79 9.7 3.3 1.9 1 1 0 1 1 1 0 Prefoldin subunit DUF1664 PF07889.12 CDJ87572.1 - 1.2 9.2 3.3 1.7 8.7 1.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CCDC-167 PF15188.6 CDJ87572.1 - 1.2 9.5 8.8 1.8 9.0 7.9 1.7 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 zf-RING_2 PF13639.6 CDJ87572.1 - 2.6 8.5 7.2 0.6 10.5 1.9 2.1 2 0 0 2 2 2 0 Ring finger domain Baculo_IE-1 PF05290.11 CDJ87572.1 - 3.6 7.5 6.7 0.37 10.7 0.9 2.1 2 1 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-Mss51 PF13824.6 CDJ87572.1 - 5.7 7.1 7.9 5.9 7.1 0.9 3.2 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 YhfH PF14149.6 CDJ87572.1 - 7.3 6.7 9.3 6 6.9 2.9 2.5 2 0 0 2 2 2 0 YhfH-like protein DUF4140 PF13600.6 CDJ87572.1 - 9.5 6.7 8.4 85 3.7 8.4 2.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Collagen PF01391.18 CDJ87573.1 - 2e-19 69.1 100.7 2.5e-07 30.3 37.7 4.2 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ87573.1 - 0.002 18.1 0.0 0.0026 17.8 0.0 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain CENP-Q PF13094.6 CDJ87573.1 - 0.07 13.3 0.0 0.096 12.9 0.0 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit 7tm_1 PF00001.21 CDJ87574.1 - 4.5e-22 78.6 7.6 6.1e-22 78.2 7.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 CDJ87574.1 - 2.2e-07 30.9 0.7 3.2e-07 30.4 0.7 1.2 1 0 0 1 1 1 1 Olfactory receptor Sigma_reg_N PF13800.6 CDJ87574.1 - 0.22 11.8 1.8 0.67 10.3 0.2 2.2 2 0 0 2 2 2 0 Sigma factor regulator N-terminal WH1 PF00568.23 CDJ87575.1 - 7.3e-23 80.6 0.2 1.3e-22 79.8 0.2 1.4 1 0 0 1 1 1 1 WH1 domain DCP1 PF06058.13 CDJ87575.1 - 0.018 14.9 0.1 0.034 14.1 0.1 1.4 1 0 0 1 1 1 0 Dcp1-like decapping family Ribonuclease_T2 PF00445.18 CDJ87576.1 - 8.1e-46 156.5 0.0 1.1e-45 156.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Carboxyl_trans PF01039.22 CDJ87577.1 - 1.5e-130 436.1 0.0 1.9e-130 435.8 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain DUF5418 PF17439.2 CDJ87579.1 - 0.19 11.8 0.1 0.21 11.7 0.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5418) SH2 PF00017.24 CDJ87580.1 - 4.7e-10 39.4 0.1 8.8e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 SH2 domain Apolipoprotein PF01442.18 CDJ87582.1 - 0.085 12.7 0.3 9.2 6.1 0.1 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain TAF6_C PF07571.13 CDJ87582.1 - 0.11 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain RVT_1 PF00078.27 CDJ87583.1 - 2.9e-20 72.7 0.0 3.9e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDJ87584.1 - 0.0036 17.1 0.0 0.014 15.2 0.0 2.1 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase VWA PF00092.28 CDJ87585.1 - 1e-10 42.2 0.0 2.3e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Macoilin PF09726.9 CDJ87585.1 - 0.78 8.2 11.3 1.1 7.7 11.3 1.1 1 0 0 1 1 1 0 Macoilin family PIN_4 PF13638.6 CDJ87586.1 - 5.1e-19 68.9 0.1 1.8e-18 67.0 0.0 1.8 2 0 0 2 2 2 1 PIN domain PIN_4 PF13638.6 CDJ87587.1 - 5.9e-19 68.6 2.3 6.2e-19 68.6 0.2 2.1 2 0 0 2 2 2 1 PIN domain PIN_9 PF18477.1 CDJ87587.1 - 0.051 13.9 1.5 0.27 11.6 0.0 2.7 3 0 0 3 3 3 0 PIN like domain LIM PF00412.22 CDJ87588.1 - 1.3e-32 111.8 42.7 8.5e-12 45.1 4.8 3.1 3 0 0 3 3 3 3 LIM domain Laminin_N PF00055.17 CDJ87589.1 - 1.7e-68 230.8 0.0 1.7e-68 230.8 0.0 2.5 2 1 1 3 3 3 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 CDJ87589.1 - 5.1e-23 81.0 63.3 5.9e-10 39.1 12.1 4.7 6 0 0 6 6 6 3 Laminin EGF domain NTR PF01759.21 CDJ87589.1 - 2.5e-06 27.3 0.5 4.7e-06 26.4 0.5 1.4 1 0 0 1 1 1 1 UNC-6/NTR/C345C module RVT_1 PF00078.27 CDJ87590.1 - 1.5e-31 109.6 0.0 2.4e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDJ87590.1 - 2.1e-31 108.3 0.0 8.4e-31 106.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ87590.1 - 6.1e-29 100.0 0.0 3e-28 97.8 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ87590.1 - 2.5e-06 27.5 0.9 7.9e-06 25.9 0.0 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 CDJ87590.1 - 4.5e-05 23.9 0.0 0.00012 22.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 CDJ87590.1 - 0.00013 21.9 1.8 0.00024 21.1 1.8 1.5 1 0 0 1 1 1 1 Zinc knuckle RVP PF00077.20 CDJ87590.1 - 0.12 12.7 0.2 0.38 11.1 0.0 1.9 2 0 0 2 2 2 0 Retroviral aspartyl protease ShK PF01549.24 CDJ87591.1 - 0.039 14.5 2.4 0.068 13.7 2.4 1.3 1 0 0 1 1 1 0 ShK domain-like E1_dh PF00676.20 CDJ87592.1 - 1.8e-97 326.0 5.3 5.4e-49 166.7 1.7 2.1 1 1 1 2 2 2 2 Dehydrogenase E1 component Ufd2P_core PF10408.9 CDJ87593.1 - 7e-110 368.5 1.4 8.2e-110 368.3 1.4 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 CDJ87593.1 - 1.6e-26 92.2 0.4 1.6e-26 92.2 0.4 1.8 2 0 0 2 2 2 1 U-box domain RVT_1 PF00078.27 CDJ87594.1 - 3.3e-31 108.6 0.0 2.2e-18 66.6 0.0 2.9 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_1 PF00001.21 CDJ87597.1 - 2.3e-46 158.3 16.0 3.2e-46 157.8 16.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ87597.1 - 2.9e-05 23.6 17.5 0.00011 21.7 17.5 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DIX PF00778.17 CDJ87599.1 - 3.2e-10 39.7 0.0 6.3e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 DIX domain RGS PF00615.19 CDJ87599.1 - 3.4e-08 33.8 0.0 6.6e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain GIY-YIG PF01541.24 CDJ87601.1 - 0.035 14.4 0.0 0.079 13.2 0.0 1.7 1 0 0 1 1 1 0 GIY-YIG catalytic domain BTB PF00651.31 CDJ87602.1 - 5.6e-07 29.8 0.4 1.4e-06 28.5 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain DUF1265 PF06887.14 CDJ87602.1 - 0.017 15.1 2.9 0.033 14.2 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1265) Innexin PF00876.18 CDJ87604.1 - 4.9e-74 249.7 2.6 5.8e-74 249.5 2.6 1.1 1 0 0 1 1 1 1 Innexin DUF5470 PF17564.2 CDJ87604.1 - 0.084 13.1 0.3 0.59 10.4 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5470) zf-CCCH PF00642.24 CDJ87605.1 - 9.9e-11 41.3 12.6 1.1e-05 25.2 2.7 2.7 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDJ87605.1 - 9e-06 25.4 10.1 0.0034 17.1 0.9 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 CDJ87605.1 - 0.00071 20.2 0.3 0.2 12.3 0.0 2.4 2 0 0 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 CDJ87605.1 - 0.0021 18.4 7.6 0.43 11.1 0.1 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 CDJ87605.1 - 0.85 9.8 12.6 0.88 9.7 0.2 2.7 3 0 0 3 3 3 0 Zinc finger domain rve PF00665.26 CDJ87606.1 - 2.2e-23 82.7 0.1 7.5e-23 81.0 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ87606.1 - 1.9e-06 27.9 0.1 4.5e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CDJ87606.1 - 1.1e-05 25.1 0.0 2.5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain BTB PF00651.31 CDJ87608.1 - 1.5e-30 105.6 1.9 3.1e-30 104.7 0.8 2.0 1 1 1 2 2 2 1 BTB/POZ domain MATH PF00917.26 CDJ87608.1 - 2.4e-06 27.6 0.1 4.6e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 MATH domain BACK PF07707.15 CDJ87608.1 - 0.0011 19.0 0.6 0.019 15.0 0.0 2.9 3 0 0 3 3 3 1 BTB And C-terminal Kelch SH2 PF00017.24 CDJ87609.1 - 4.7e-10 39.4 0.1 8.8e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 SH2 domain zf-C2HC_2 PF13913.6 CDJ87612.1 - 2.1e-10 40.2 5.0 4.3e-10 39.2 0.8 2.2 2 0 0 2 2 2 1 zinc-finger of a C2HC-type DUF2318 PF10080.9 CDJ87612.1 - 0.023 14.8 0.0 0.031 14.4 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zinc_ribbon_4 PF13717.6 CDJ87612.1 - 0.052 13.5 0.3 14 5.7 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_7 PF02591.15 CDJ87612.1 - 0.056 13.6 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 C4-type zinc ribbon domain Herpes_UL52 PF03121.15 CDJ87614.1 - 2.5e-09 36.9 0.8 5.3e-09 35.9 0.8 1.5 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase Tub PF01167.18 CDJ87616.1 - 0.13 12.0 0.8 0.17 11.6 0.8 1.1 1 0 0 1 1 1 0 Tub family DDE_Tnp_1_7 PF13843.6 CDJ87617.1 - 1.2e-38 133.3 0.1 1.5e-38 133.0 0.1 1.1 1 0 0 1 1 1 1 Transposase IS4 MOLO1 PF17175.4 CDJ87619.1 - 3.4e-20 72.3 0.0 1.2e-19 70.6 0.0 1.8 1 1 0 1 1 1 1 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 CDJ87619.1 - 5e-08 33.2 0.0 7.1e-07 29.4 0.0 2.0 1 1 0 1 1 1 1 TPM domain Collagen PF01391.18 CDJ87620.1 - 1.8e-21 75.7 121.0 9.8e-09 34.9 47.3 4.0 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ87620.1 - 2.2e-20 72.5 0.2 2.7e-20 72.1 0.2 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain COX14 PF14880.6 CDJ87620.1 - 0.068 13.0 2.0 0.098 12.5 2.0 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c assembly PHO4 PF01384.20 CDJ87621.1 - 3.8e-64 216.9 5.6 6.6e-64 216.1 5.6 1.4 1 0 0 1 1 1 1 Phosphate transporter family Mob1_phocein PF03637.17 CDJ87622.1 - 2.6e-73 245.6 0.1 3.3e-73 245.3 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family TFIID_NTD2 PF04494.15 CDJ87622.1 - 0.055 13.7 0.7 0.13 12.5 0.7 1.5 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain DUF5641 PF18701.1 CDJ87623.1 - 3.7e-14 52.6 0.0 6.3e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5641) rve PF00665.26 CDJ87623.1 - 5e-05 23.5 0.0 9.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDJ87623.1 - 0.058 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Flagellar_rod PF05149.12 CDJ87624.1 - 0.13 11.7 4.5 0.47 9.9 0.0 3.1 2 2 2 4 4 4 0 Paraflagellar rod protein HSP90 PF00183.18 CDJ87626.1 - 1.5e-91 307.9 10.4 1.8e-89 301.0 6.3 2.1 1 1 1 2 2 2 2 Hsp90 protein DER1 PF04511.15 CDJ87626.1 - 3.5e-74 248.9 17.3 7.4e-74 247.8 17.3 1.6 1 0 0 1 1 1 1 Der1-like family HATPase_c_3 PF13589.6 CDJ87626.1 - 3.6e-12 46.3 0.1 7.1e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDJ87626.1 - 1.1e-08 35.6 0.1 2e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Telomere_reg-2 PF10193.9 CDJ87626.1 - 0.15 12.5 0.1 2.7 8.5 0.0 2.7 2 0 0 2 2 2 0 Telomere length regulation protein HEPN_RiboL-PSP PF18735.1 CDJ87626.1 - 0.26 11.2 3.7 0.64 9.9 0.0 2.4 2 0 0 2 2 2 0 RiboL-PSP-HEPN RVT_1 PF00078.27 CDJ87628.1 - 5.5e-22 78.4 0.0 6.5e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7TM_GPCR_Srt PF10321.9 CDJ87630.1 - 1.8e-15 56.7 18.6 2.7e-15 56.2 18.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt 7TM_GPCR_Srx PF10328.9 CDJ87630.1 - 0.00056 19.6 17.3 0.00072 19.3 17.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx CBP4 PF07960.11 CDJ87630.1 - 0.27 11.1 0.3 0.97 9.3 0.0 1.9 2 0 0 2 2 2 0 CBP4 7TM_GPCR_Srv PF10323.9 CDJ87631.1 - 1.3e-22 80.6 22.0 1.4e-22 80.4 22.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Srg PF02118.21 CDJ87631.1 - 4.7e-14 52.7 25.1 6.4e-14 52.3 25.1 1.1 1 0 0 1 1 1 1 Srg family chemoreceptor 7TM_GPCR_Srx PF10328.9 CDJ87631.1 - 3.8e-11 43.1 26.5 4.8e-11 42.8 26.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Sru PF10322.9 CDJ87631.1 - 0.00016 21.1 17.7 0.0004 19.8 17.8 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sru 7tm_1 PF00001.21 CDJ87631.1 - 0.0046 16.3 19.7 0.0094 15.3 19.4 1.6 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) PSI_PSAK PF01241.18 CDJ87631.1 - 0.0073 16.3 2.1 0.088 12.8 2.1 2.4 1 1 0 1 1 1 1 Photosystem I psaG / psaK Rogdi_lz PF10259.9 CDJ87632.1 - 1.3e-13 51.0 2.9 1.1e-12 48.0 0.1 2.1 1 1 1 2 2 2 1 Rogdi leucine zipper containing protein SlyX PF04102.12 CDJ87632.1 - 0.0045 17.6 0.4 0.0045 17.6 0.4 2.1 2 0 0 2 2 2 1 SlyX DUF1324 PF07038.11 CDJ87632.1 - 0.11 12.7 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1324) DASH_Hsk3 PF08227.11 CDJ87632.1 - 0.55 10.6 7.9 8 6.9 3.6 2.5 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like Trypan_PARP PF05887.11 CDJ87632.1 - 0.88 9.6 11.7 1.4 8.8 11.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TRPM_tetra PF16519.5 CDJ87632.1 - 4.7 7.4 5.3 12 6.1 0.7 2.8 2 2 1 3 3 3 0 Tetramerisation domain of TRPM DUF1682 PF07946.14 CDJ87633.1 - 1.2e-79 267.9 4.4 1.2e-79 267.9 4.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1682) GalP_UDP_tr_C PF02744.17 CDJ87633.1 - 9.1e-47 158.9 0.0 1.9e-46 157.9 0.0 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.22 CDJ87633.1 - 4.7e-40 138.0 1.0 4.7e-40 138.0 1.0 2.3 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF4931 PF16285.5 CDJ87633.1 - 0.06 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4931) HIT PF01230.23 CDJ87633.1 - 0.15 12.8 0.1 5.1 7.9 0.0 2.8 2 0 0 2 2 2 0 HIT domain DUF3721 PF12518.8 CDJ87633.1 - 1.4 8.8 4.2 0.3 11.0 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function PhoLip_ATPase_C PF16212.5 CDJ87636.1 - 7.8e-72 242.0 22.0 7.8e-72 242.0 22.0 2.0 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CDJ87636.1 - 4.5e-26 90.3 0.3 1.2e-25 89.0 0.3 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CDJ87636.1 - 1.2e-11 44.5 0.0 2.5e-10 40.3 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CDJ87636.1 - 1e-09 39.0 9.5 1.9e-05 25.0 1.9 3.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CDJ87636.1 - 2.7e-05 23.8 0.3 8.3e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CDJ87636.1 - 0.0059 16.4 1.4 0.014 15.2 1.4 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PMP1_2 PF08114.11 CDJ87636.1 - 0.33 10.7 5.6 0.052 13.3 0.5 2.3 2 0 0 2 2 2 0 ATPase proteolipid family Ras PF00071.22 CDJ87637.1 - 8.3e-34 116.5 0.6 2e-33 115.3 0.2 1.7 1 1 1 2 2 2 1 Ras family Roc PF08477.13 CDJ87637.1 - 6.9e-22 77.9 0.2 3.2e-21 75.8 0.1 2.0 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ87637.1 - 4e-09 36.2 0.1 7.6e-09 35.3 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ87637.1 - 4.8e-05 22.8 0.1 0.0001 21.8 0.1 1.5 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDJ87637.1 - 0.0026 17.8 0.0 0.0056 16.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ87637.1 - 0.072 13.0 0.0 0.15 11.9 0.0 1.5 1 1 0 1 1 1 0 RsgA GTPase Ion_trans PF00520.31 CDJ87638.1 - 3.1e-107 357.4 91.5 9.1e-33 113.5 18.7 4.5 4 1 1 5 5 5 5 Ion transport protein DUF3742 PF12553.8 CDJ87638.1 - 0.08 13.1 2.1 2.1 8.5 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3742) PKD_channel PF08016.12 CDJ87638.1 - 0.085 11.5 63.1 0.032 12.9 13.7 5.7 5 0 0 5 5 5 0 Polycystin cation channel PsaF PF17550.2 CDJ87638.1 - 0.53 9.8 3.7 0.38 10.2 0.4 2.5 2 0 0 2 2 2 0 Family of unknown function IP_trans PF02121.18 CDJ87639.1 - 3.4e-27 95.6 0.0 3.7e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Metallophos PF00149.28 CDJ87640.1 - 2.8e-40 139.0 0.0 3.8e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDJ87640.1 - 0.0024 18.3 0.2 0.0049 17.3 0.2 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 CDJ87640.1 - 0.035 13.7 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Glutaredoxin PF00462.24 CDJ87641.1 - 2.9e-19 69.1 0.1 5.2e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 Glutaredoxin Ribosomal_L36 PF00444.18 CDJ87642.1 - 4e-14 52.5 3.9 5.6e-14 52.1 3.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 Ecm29 PF13001.7 CDJ87643.1 - 4.7e-72 243.3 20.1 1.6e-69 234.9 13.8 3.0 2 0 0 2 2 2 2 Proteasome stabiliser HEAT_2 PF13646.6 CDJ87643.1 - 2e-08 34.5 13.3 0.45 10.9 0.1 6.3 5 0 0 5 5 5 4 HEAT repeats HEAT PF02985.22 CDJ87643.1 - 9.3e-08 31.7 12.6 0.0011 19.0 0.0 9.0 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.6 CDJ87643.1 - 9.8e-08 32.4 11.4 0.0035 17.8 0.2 9.2 9 1 1 10 10 10 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CDJ87643.1 - 3.7e-06 27.5 0.1 1.6 9.4 0.0 5.9 3 1 2 5 5 5 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CDJ87643.1 - 0.00014 21.9 2.5 0.59 10.2 0.0 4.2 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DUF2267 PF10025.9 CDJ87643.1 - 0.0032 17.7 1.5 0.38 11.0 0.3 3.5 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2267) RICTOR_V PF14668.6 CDJ87643.1 - 0.044 14.0 0.3 7.4 6.9 0.0 3.8 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 RICTOR_M PF14666.6 CDJ87643.1 - 0.067 13.0 1.4 0.76 9.6 0.0 3.6 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, middle domain Biotin_carb_C PF02785.19 CDJ87643.1 - 0.076 13.1 0.7 1.2 9.2 0.1 2.8 2 0 0 2 2 2 0 Biotin carboxylase C-terminal domain TetR_C_8 PF14278.6 CDJ87643.1 - 0.15 12.2 0.0 12 6.1 0.0 3.4 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region SNF2_N PF00176.23 CDJ87644.1 - 2.5e-56 190.9 0.7 4.3e-56 190.1 0.7 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ87644.1 - 1.2e-20 73.9 0.3 9.2e-18 64.6 0.0 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ87644.1 - 4.2e-11 43.1 0.0 1.2e-10 41.7 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CDJ87644.1 - 5.6e-06 25.7 0.0 1.2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CENP-P PF13096.6 CDJ87644.1 - 0.0022 17.7 0.5 1 9.0 0.2 2.4 2 0 0 2 2 2 2 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P HHH_3 PF12836.7 CDJ87644.1 - 0.014 15.6 0.0 0.056 13.7 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif zf-C4 PF00105.18 CDJ87645.1 - 1.7e-20 73.2 16.7 2.8e-20 72.5 16.7 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Orthoreo_P10 PF07204.11 CDJ87646.1 - 0.12 12.3 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Transposase_1 PF01359.18 CDJ87649.1 - 2.9e-17 62.3 1.5 2.9e-17 62.2 0.1 1.8 2 0 0 2 2 2 1 Transposase (partial DDE domain) HTH_48 PF17906.1 CDJ87649.1 - 2.7e-11 43.4 0.0 4.5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 CDJ87649.1 - 4.1e-05 24.1 0.4 0.00014 22.4 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 CDJ87649.1 - 9.7e-05 22.5 0.1 0.00018 21.7 0.1 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 CDJ87649.1 - 0.0011 18.8 0.1 0.0023 17.7 0.1 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_24 PF13412.6 CDJ87649.1 - 0.0057 16.2 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 CDJ87649.1 - 0.013 15.5 0.1 0.025 14.5 0.1 1.4 1 0 0 1 1 1 0 HTH domain HTH_AsnC-type PF13404.6 CDJ87649.1 - 0.023 14.5 0.0 0.05 13.4 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain GerE PF00196.19 CDJ87649.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_Tnp_IS630 PF01710.16 CDJ87649.1 - 0.19 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Transposase Cation_ATPase_C PF00689.21 CDJ87650.1 - 1.8e-42 145.1 12.6 1.8e-42 145.1 3.4 2.4 2 0 0 2 2 2 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CDJ87650.1 - 5.1e-22 77.8 0.0 1.2e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CDJ87650.1 - 1.3e-14 55.0 0.1 1.5e-11 45.0 0.1 2.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase ATP_Ca_trans_C PF12424.8 CDJ87650.1 - 5.4e-12 46.0 0.1 1.5e-11 44.6 0.1 1.8 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal Hydrolase_3 PF08282.12 CDJ87650.1 - 1.1e-07 31.8 1.2 2.6e-05 24.1 0.7 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CDJ87650.1 - 8.4e-06 25.4 2.0 8.4e-06 25.4 2.0 2.2 3 0 0 3 3 3 1 E1-E2 ATPase DUF2976 PF11190.8 CDJ87650.1 - 0.14 11.9 1.5 0.58 10.0 1.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) FNIP_M PF14637.6 CDJ87652.1 - 4e-26 92.4 0.1 7e-26 91.6 0.1 1.4 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_N PF14636.6 CDJ87652.1 - 0.0037 18.3 7.7 0.0039 18.2 0.0 3.0 2 2 0 2 2 2 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.6 CDJ87653.1 - 8.9e-27 94.6 0.1 1e-26 94.3 0.1 1.0 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_C PF14638.6 CDJ87654.1 - 1.5e-40 138.9 0.0 2.1e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Folliculin-interacting protein C-terminus FNIP_M PF14637.6 CDJ87654.1 - 4.3e-06 26.9 0.2 9.5e-06 25.8 0.2 1.5 2 0 0 2 2 2 1 Folliculin-interacting protein middle domain PHD PF00628.29 CDJ87655.1 - 0.00089 19.1 6.2 0.00089 19.1 6.2 2.3 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 CDJ87655.1 - 3.3 7.3 12.3 21 4.7 12.3 2.3 1 1 0 1 1 1 0 PHD-finger Pkinase PF00069.25 CDJ87656.1 - 4.2e-61 206.6 0.0 5.8e-61 206.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ87656.1 - 7.4e-30 104.1 0.1 1.1e-29 103.5 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ87656.1 - 0.00013 21.4 0.3 0.00021 20.7 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ87656.1 - 0.0007 19.6 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CDJ87656.1 - 0.0018 17.6 0.3 0.0063 15.9 0.3 2.0 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CDJ87656.1 - 0.021 14.4 0.2 0.033 13.8 0.2 1.3 1 0 0 1 1 1 0 RIO1 family Collagen PF01391.18 CDJ87657.1 - 2.1e-22 78.6 98.8 2.5e-08 33.5 32.9 3.9 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ87657.1 - 0.00014 21.8 0.3 0.00019 21.4 0.3 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain DUF641 PF04859.12 CDJ87658.1 - 0.088 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Radial_spoke_3 PF06098.11 CDJ87659.1 - 0.00091 18.6 6.4 0.00091 18.6 6.4 1.8 2 1 0 2 2 2 1 Radial spoke protein 3 FlxA PF14282.6 CDJ87659.1 - 0.017 15.1 0.5 0.017 15.1 0.5 1.8 2 0 0 2 2 2 0 FlxA-like protein STI1 PF17830.1 CDJ87660.1 - 0.012 15.6 0.0 1.1 9.2 0.0 2.9 3 0 0 3 3 3 0 STI1 domain Mog1 PF04603.12 CDJ87660.1 - 0.44 10.9 2.1 1.7 9.0 0.2 2.1 2 0 0 2 2 2 0 Ran-interacting Mog1 protein Na_H_Exchanger PF00999.21 CDJ87661.1 - 7.7e-61 206.0 45.2 1e-60 205.6 45.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pex24p PF06398.11 CDJ87661.1 - 0.064 12.2 0.0 0.064 12.2 0.0 2.3 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin COX8 PF02285.15 CDJ87661.1 - 3.7 7.5 6.7 0.4 10.6 0.5 2.7 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII Collagen PF01391.18 CDJ87663.1 - 9.7e-26 89.3 83.3 2.1e-10 40.2 24.0 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Xol-1_GHMP-like PF09109.10 CDJ87664.1 - 0.079 12.8 0.2 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 Switch protein XOL-1, GHMP-like zf-C2H2_4 PF13894.6 CDJ87664.1 - 1.3 10.1 11.0 11 7.2 4.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Ras PF00071.22 CDJ87666.1 - 7e-18 64.7 0.2 1.3e-17 63.9 0.2 1.5 1 1 0 1 1 1 1 Ras family Arf PF00025.21 CDJ87666.1 - 0.081 12.4 0.1 0.15 11.5 0.1 1.6 1 1 0 1 1 1 0 ADP-ribosylation factor family MLANA PF14991.6 CDJ87667.1 - 0.093 13.0 1.5 0.14 12.4 1.5 1.2 1 0 0 1 1 1 0 Protein melan-A DUF4713 PF15831.5 CDJ87667.1 - 0.23 11.9 10.0 0.63 10.5 10.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) DUF4690 PF15756.5 CDJ87667.1 - 5.7 7.6 5.6 11 6.7 5.6 1.4 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DnaJ PF00226.31 CDJ87668.1 - 2.2e-11 43.7 0.4 2.2e-11 43.7 0.4 2.0 2 1 0 2 2 2 1 DnaJ domain DUF3391 PF11871.8 CDJ87668.1 - 0.18 12.3 8.1 1.6 9.3 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) Cyclin_N PF00134.23 CDJ87669.1 - 2.6e-10 40.1 1.5 3.7e-10 39.6 0.7 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain RRM_1 PF00076.22 CDJ87670.1 - 3.5e-13 49.2 0.0 5.9e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSRP PF17069.5 CDJ87670.1 - 0.00052 19.7 40.3 0.00052 19.7 40.3 2.3 2 0 0 2 2 2 1 Arginine/Serine-Rich protein 1 PRP38_assoc PF12871.7 CDJ87670.1 - 0.0019 18.8 43.4 0.0019 18.8 43.4 3.0 3 0 0 3 3 3 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term GRP PF07172.11 CDJ87670.1 - 0.0023 18.6 3.2 0.0023 18.6 3.2 2.1 2 0 0 2 2 2 1 Glycine rich protein family Apt1 PF10351.9 CDJ87670.1 - 4.7 6.0 30.4 0.015 14.2 14.8 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain CPSF100_C PF13299.6 CDJ87670.1 - 4.9 7.3 9.3 20 5.3 9.3 2.0 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PI-PLC-X PF00388.19 CDJ87672.1 - 7.2e-50 168.4 0.0 1.2e-49 167.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CDJ87672.1 - 6.9e-28 97.3 0.0 2.1e-27 95.8 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 CDJ87672.1 - 1.2e-19 70.5 0.0 2.4e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain EF-hand_10 PF14788.6 CDJ87672.1 - 3.2e-10 39.7 0.9 1.7e-09 37.4 0.5 2.3 1 1 1 2 2 2 1 EF hand EF-hand_like PF09279.11 CDJ87672.1 - 5.5e-10 39.6 0.7 1.9e-09 37.9 0.1 2.3 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_6 PF13405.6 CDJ87672.1 - 5.7e-06 25.8 0.1 0.0095 15.8 0.0 3.6 3 1 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 CDJ87672.1 - 1.3e-05 25.5 1.4 5.4e-05 23.6 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CDJ87672.1 - 3.7e-05 23.0 0.0 0.011 15.2 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 CDJ87672.1 - 6.1e-05 22.3 0.0 0.0037 16.7 0.0 2.7 2 0 0 2 2 2 1 EF hand PH PF00169.29 CDJ87672.1 - 0.00044 20.7 0.2 0.0037 17.8 0.0 2.3 2 0 0 2 2 2 1 PH domain EF-hand_8 PF13833.6 CDJ87672.1 - 0.00053 19.8 0.6 0.26 11.2 0.0 3.4 3 1 1 4 4 3 1 EF-hand domain pair GDPD PF03009.17 CDJ87672.1 - 0.013 15.2 0.1 0.05 13.3 0.0 2.0 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family PH_4 PF15404.6 CDJ87672.1 - 0.051 13.4 0.6 0.077 12.8 0.0 1.6 2 0 0 2 2 2 0 Pleckstrin homology domain PH_12 PF16457.5 CDJ87672.1 - 0.059 13.9 0.0 0.17 12.4 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain SPARC_Ca_bdg PF10591.9 CDJ87672.1 - 1.4 9.2 4.9 0.31 11.4 0.5 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Innexin PF00876.18 CDJ87673.1 - 1.4e-101 340.4 9.9 3.3e-101 339.1 9.9 1.5 1 1 0 1 1 1 1 Innexin Mem_trans PF03547.18 CDJ87673.1 - 0.19 10.1 0.0 0.19 10.1 0.0 1.7 2 0 0 2 2 2 0 Membrane transport protein Lactamase_B PF00753.27 CDJ87674.1 - 2.9e-22 79.6 0.1 4.8e-22 78.9 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 CDJ87674.1 - 1.7e-11 43.9 0.0 3.4e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 CDJ87674.1 - 2.1e-07 30.7 0.1 6.2e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CDJ87674.1 - 2.1e-06 27.7 0.0 3.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 CDJ87674.1 - 0.0048 16.3 0.0 0.0089 15.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RVT_1 PF00078.27 CDJ87675.1 - 3.9e-19 69.0 0.0 6e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TSC22 PF01166.18 CDJ87676.1 - 3.9e-25 87.9 1.6 5.7e-25 87.4 1.6 1.2 1 0 0 1 1 1 1 TSC-22/dip/bun family SOGA PF11365.8 CDJ87676.1 - 0.0014 19.7 0.2 0.0019 19.3 0.2 1.3 1 0 0 1 1 1 1 Protein SOGA Shugoshin_N PF07558.11 CDJ87676.1 - 0.002 18.0 1.7 0.0033 17.3 1.7 1.3 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region bZIP_2 PF07716.15 CDJ87676.1 - 0.0043 17.1 1.7 0.0043 17.1 1.7 1.9 2 0 0 2 2 2 1 Basic region leucine zipper CCDC85 PF10226.9 CDJ87676.1 - 0.013 15.2 0.2 0.016 14.9 0.2 1.2 1 0 0 1 1 1 0 CCDC85 family PilJ PF13675.6 CDJ87676.1 - 0.014 15.4 0.4 0.021 14.8 0.4 1.4 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term K-box PF01486.17 CDJ87676.1 - 0.016 15.4 0.1 0.023 14.8 0.1 1.2 1 0 0 1 1 1 0 K-box region bZIP_1 PF00170.21 CDJ87676.1 - 0.018 15.1 1.3 0.032 14.3 1.3 1.5 1 1 0 1 1 1 0 bZIP transcription factor DUF4599 PF15371.6 CDJ87676.1 - 0.022 15.3 0.1 0.036 14.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4599) BMFP PF04380.13 CDJ87676.1 - 0.024 15.1 1.0 0.048 14.1 1.0 1.5 1 0 0 1 1 1 0 Membrane fusogenic activity Lebercilin PF15619.6 CDJ87676.1 - 0.026 14.2 0.9 0.036 13.7 0.9 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF2730 PF10805.8 CDJ87676.1 - 0.032 14.3 0.1 0.044 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) ATG16 PF08614.11 CDJ87676.1 - 0.033 14.4 1.4 0.04 14.1 1.3 1.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) ABC_tran_CTD PF16326.5 CDJ87676.1 - 0.047 13.9 0.6 0.047 13.9 0.6 1.7 2 1 0 2 2 1 0 ABC transporter C-terminal domain DivIC PF04977.15 CDJ87676.1 - 0.052 13.3 2.2 0.074 12.8 1.8 1.5 1 1 0 1 1 1 0 Septum formation initiator YabA PF06156.13 CDJ87676.1 - 0.056 14.1 0.5 0.073 13.7 0.5 1.2 1 0 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 CDJ87676.1 - 0.076 13.5 4.1 0.12 12.8 4.1 1.4 1 1 0 1 1 1 0 Cell division protein ZapB Fzo_mitofusin PF04799.13 CDJ87676.1 - 0.11 12.0 0.4 0.14 11.7 0.4 1.1 1 0 0 1 1 1 0 fzo-like conserved region FlaC_arch PF05377.11 CDJ87676.1 - 0.13 12.7 1.3 0.25 11.7 1.3 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 CDJ87676.1 - 4 8.1 6.2 15 6.3 4.4 2.4 2 1 0 2 2 2 0 SlyX TPR_17 PF13431.6 CDJ87678.1 - 1.2e-05 25.4 2.5 0.0011 19.2 0.1 3.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ87678.1 - 0.0011 19.5 0.5 26 6.0 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat FliG_C PF01706.16 CDJ87678.1 - 0.06 13.5 0.0 0.25 11.5 0.0 2.0 2 0 0 2 2 2 0 FliG C-terminal domain ESCRT-II PF05871.12 CDJ87678.1 - 0.075 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 ESCRT-II complex subunit TPR_2 PF07719.17 CDJ87678.1 - 0.11 12.6 7.1 1.6 9.0 0.1 4.7 4 1 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ87678.1 - 0.12 12.3 10.0 1.7 8.6 0.2 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ87678.1 - 0.35 11.6 1.6 23 5.7 0.1 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ87678.1 - 0.68 10.5 5.5 8 7.1 0.0 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ87678.1 - 0.78 10.0 8.6 18 5.6 0.4 4.3 5 1 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 IRS PF02174.17 CDJ87679.1 - 0.0045 16.9 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 PTB domain (IRS-1 type) Coatomer_WDAD PF04053.14 CDJ87680.1 - 9.5e-07 28.2 2.8 0.035 13.2 0.0 3.2 3 0 0 3 3 3 3 Coatomer WD associated region TPR_7 PF13176.6 CDJ87680.1 - 0.00034 20.4 12.4 0.04 14.0 0.7 5.8 7 0 0 7 7 7 1 Tetratricopeptide repeat RPN1_RPN2_N PF17781.1 CDJ87680.1 - 0.007 15.8 0.2 0.007 15.8 0.2 2.0 3 0 0 3 3 3 1 RPN1/RPN2 N-terminal domain C1_2 PF03107.16 CDJ87680.1 - 0.019 15.2 0.7 0.081 13.3 0.7 2.1 1 0 0 1 1 1 0 C1 domain Clathrin PF00637.20 CDJ87680.1 - 0.054 13.4 3.6 0.44 10.4 0.3 3.2 2 1 1 3 3 3 0 Region in Clathrin and VPS zf_C2HC_14 PF18574.1 CDJ87680.1 - 0.071 12.9 2.7 9.6 6.1 0.1 2.7 2 0 0 2 2 2 0 C2HC Zing finger domain TPR_2 PF07719.17 CDJ87680.1 - 0.13 12.4 8.0 0.13 12.4 0.4 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ87680.1 - 0.3 11.0 2.8 0.42 10.6 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ87680.1 - 1.3 9.4 10.5 0.72 10.2 0.7 4.9 4 2 1 5 5 5 0 Tetratricopeptide repeat Ceramidase PF05875.12 CDJ87681.1 - 8.8e-39 133.5 7.0 9.7e-39 133.4 7.0 1.0 1 0 0 1 1 1 1 Ceramidase ArsA_ATPase PF02374.15 CDJ87682.1 - 3e-114 381.3 0.0 3.4e-114 381.1 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 CDJ87682.1 - 2e-12 47.4 0.0 4.8e-12 46.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 CDJ87682.1 - 9.6e-11 41.8 0.0 3.2e-10 40.2 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 CDJ87682.1 - 3.6e-06 26.6 0.1 0.00011 21.7 0.0 2.3 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 CDJ87682.1 - 4.7e-05 23.0 0.1 0.00011 21.8 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Zeta_toxin PF06414.12 CDJ87682.1 - 0.00076 18.8 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin SRP54 PF00448.22 CDJ87682.1 - 0.0009 18.9 0.0 0.011 15.4 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 CDJ87682.1 - 0.00094 18.7 0.0 0.002 17.6 0.0 1.5 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Elf1 PF05129.13 CDJ87682.1 - 0.0014 18.7 0.0 0.0036 17.3 0.0 1.6 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like NB-ARC PF00931.22 CDJ87682.1 - 0.008 15.4 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_25 PF13481.6 CDJ87682.1 - 0.05 13.2 0.3 0.13 11.8 0.3 1.8 1 1 0 1 1 1 0 AAA domain zinc_ribbon_4 PF13717.6 CDJ87682.1 - 0.057 13.3 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain MeaB PF03308.16 CDJ87682.1 - 0.059 12.3 0.0 6.5 5.7 0.0 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PhoH PF02562.16 CDJ87682.1 - 0.061 12.8 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein PIF1 PF05970.14 CDJ87682.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase VirC1 PF07015.11 CDJ87682.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein Pkinase PF00069.25 CDJ87683.1 - 6.8e-51 173.2 0.0 8.5e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ87683.1 - 1.2e-28 100.1 0.0 1.5e-28 99.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ87683.1 - 3.5e-07 29.8 0.0 4.4e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDJ87683.1 - 2.5e-06 27.0 0.1 3.6e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDJ87683.1 - 0.0025 16.8 0.2 0.0035 16.3 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CDJ87683.1 - 0.016 15.1 0.1 0.095 12.6 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ87683.1 - 0.017 13.9 0.0 0.019 13.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase YukC PF10140.9 CDJ87683.1 - 0.038 12.8 0.0 0.05 12.4 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Pkinase PF00069.25 CDJ87684.1 - 3.5e-69 233.1 0.0 5e-69 232.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ87684.1 - 5.8e-34 117.5 0.0 8.4e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CDJ87684.1 - 8e-08 32.9 5.2 1.9e-07 31.6 5.2 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 CDJ87684.1 - 8.9e-06 25.2 0.1 3.1e-05 23.5 0.0 1.9 2 1 0 2 2 2 1 Kinase-like FTA2 PF13095.6 CDJ87684.1 - 0.00023 20.8 0.1 0.61 9.7 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CDJ87684.1 - 0.00095 18.0 0.0 0.0015 17.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDJ87684.1 - 0.0037 16.6 0.2 0.016 14.6 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDJ87684.1 - 0.1 11.5 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 CDJ87684.1 - 0.14 11.2 0.0 0.29 10.2 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 APH PF01636.23 CDJ87684.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Y_phosphatase PF00102.27 CDJ87685.1 - 7.1e-63 212.3 0.0 8.9e-63 212.0 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CDJ87685.1 - 0.0022 18.0 0.2 0.005 16.8 0.1 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 CDJ87685.1 - 0.021 14.6 0.9 0.052 13.4 0.9 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain SOBP PF15279.6 CDJ87687.1 - 8.5 6.9 12.8 19 5.8 12.8 1.6 1 0 0 1 1 1 0 Sine oculis-binding protein WD40_4 PF16300.5 CDJ87688.1 - 2.4e-17 62.6 0.0 4.6e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Type of WD40 repeat DUF1899 PF08953.11 CDJ87688.1 - 4.2e-14 52.2 0.0 7.8e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 CDJ87688.1 - 1.6e-11 44.5 0.2 0.049 14.5 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ87688.1 - 4.5e-06 26.9 0.1 0.026 14.8 0.0 2.9 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CDJ87688.1 - 0.03 13.9 0.0 0.085 12.4 0.0 1.8 2 0 0 2 2 2 0 PQQ-like domain CAT_RBD PF03123.15 CDJ87688.1 - 0.16 12.0 0.1 0.69 9.9 0.0 2.0 2 0 0 2 2 2 0 CAT RNA binding domain TFIIA PF03153.13 CDJ87688.1 - 3.5 7.5 11.0 4.8 7.1 11.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MCM_OB PF17207.3 CDJ87689.1 - 1e-21 77.1 1.6 2.1e-21 76.0 1.4 1.6 2 0 0 2 2 2 1 MCM OB domain MCM_N PF14551.6 CDJ87689.1 - 1e-16 61.4 0.7 1.6e-16 60.8 0.7 1.3 1 0 0 1 1 1 1 MCM N-terminal domain YfkD PF14167.6 CDJ87689.1 - 0.0094 15.2 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 YfkD-like protein DUF4378 PF14309.6 CDJ87690.1 - 0.031 14.6 0.2 0.038 14.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) PARG_cat PF05028.14 CDJ87691.1 - 1.5e-110 369.7 0.0 2.5e-110 368.9 0.0 1.3 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) F-protein PF00469.20 CDJ87691.1 - 3.8 7.1 7.4 10 5.7 0.0 2.5 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef DUF932 PF06067.11 CDJ87692.1 - 0.018 14.8 0.0 0.025 14.4 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF932) Pkinase PF00069.25 CDJ87693.1 - 2.9e-39 135.0 0.0 3.7e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ87693.1 - 3e-36 125.0 0.0 3.9e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ87693.1 - 0.00014 21.3 0.0 0.0043 16.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like SOUL PF04832.12 CDJ87693.1 - 0.15 12.2 0.0 0.25 11.5 0.0 1.2 1 0 0 1 1 1 0 SOUL heme-binding protein CLP1_P PF16575.5 CDJ87695.1 - 9.6e-38 129.9 0.0 1.4e-37 129.3 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 CDJ87695.1 - 0.011 16.2 0.0 0.44 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 CDJ87695.1 - 0.026 14.5 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 CDJ87695.1 - 0.031 14.8 0.0 0.053 14.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 CDJ87695.1 - 0.033 14.3 0.0 0.061 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 CDJ87695.1 - 0.067 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 CDJ87695.1 - 0.084 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CDJ87695.1 - 0.088 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase APS_kinase PF01583.20 CDJ87695.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_10 PF12846.7 CDJ87695.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain RHD3 PF05879.12 CDJ87695.1 - 0.12 10.5 0.0 0.16 10.1 0.0 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) CbiA PF01656.23 CDJ87695.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 CDJ87695.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 CDJ87695.1 - 0.18 12.1 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 CDJ87695.1 - 0.2 11.9 0.0 0.39 10.9 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MipZ PF09140.11 CDJ87695.1 - 0.23 10.7 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ ATG101 PF07855.12 CDJ87696.1 - 2e-30 105.8 0.0 2.9e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 101 Otopetrin PF03189.13 CDJ87697.1 - 2.1e-23 82.9 7.5 2.1e-23 82.9 7.5 1.7 2 0 0 2 2 2 1 Otopetrin Neuraminidase PF18413.1 CDJ87698.1 - 0.06 13.0 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 Neuraminidase-like domain DUF1664 PF07889.12 CDJ87698.1 - 0.16 12.0 0.6 0.36 10.9 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FSAP_sig_propep PF03032.15 CDJ87698.1 - 5.7 7.0 9.8 38 4.4 9.8 2.4 1 1 0 1 1 1 0 Frog skin active peptide family signal and propeptide Hanta_G2 PF01561.16 CDJ87699.1 - 0.08 11.5 0.2 0.11 11.1 0.2 1.1 1 0 0 1 1 1 0 Hantavirus glycoprotein G2 Aminotran_1_2 PF00155.21 CDJ87703.1 - 2.1e-37 129.1 0.0 3.6e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Motile_Sperm PF00635.26 CDJ87703.1 - 4.4e-08 32.9 0.0 1.5e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Poxvirus_B22R PF04395.12 CDJ87703.1 - 4.5 6.7 9.0 18 4.8 0.3 4.0 3 0 0 3 3 3 0 Poxvirus B22R protein Orn_Arg_deC_N PF02784.16 CDJ87704.1 - 2.1e-47 161.6 0.0 3.5e-47 160.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 CDJ87704.1 - 6.9e-07 29.4 0.1 1.9e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DC_STAMP PF07782.13 CDJ87705.1 - 1.3e-06 28.4 1.3 1.4e-06 28.3 1.3 1.0 1 0 0 1 1 1 1 DC-STAMP-like protein Acetyltransf_1 PF00583.25 CDJ87707.1 - 9.6e-18 64.5 0.0 1.5e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDJ87707.1 - 9e-09 35.3 0.0 1.2e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDJ87707.1 - 1.3e-08 35.1 0.1 2.2e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDJ87707.1 - 1.7e-08 34.3 0.1 3e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 CDJ87707.1 - 0.00017 21.3 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CDJ87707.1 - 0.0038 17.9 0.0 0.0069 17.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 CDJ87707.1 - 0.012 15.8 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PaaX PF07848.12 CDJ87707.1 - 0.051 13.8 0.3 0.14 12.4 0.3 1.7 1 1 0 1 1 1 0 PaaX-like protein Acetyltransf_9 PF13527.7 CDJ87707.1 - 0.13 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Calx-beta PF03160.14 CDJ87708.1 - 7e-57 189.8 6.4 9.8e-30 102.7 0.7 2.9 3 0 0 3 3 3 2 Calx-beta domain Na_Ca_ex PF01699.24 CDJ87708.1 - 2.3e-53 180.2 30.6 3.9e-29 101.6 9.6 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Na_Ca_ex_C PF16494.5 CDJ87708.1 - 8.9e-30 103.8 1.3 2.4e-29 102.4 1.3 1.8 1 0 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain Proteasom_PSMB PF10508.9 CDJ87709.1 - 1.5e-64 218.3 0.3 1.9e-64 218.0 0.3 1.0 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit DUF577 PF04510.12 CDJ87709.1 - 0.068 13.1 0.3 0.93 9.4 0.1 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF577) Drf_FH3 PF06367.16 CDJ87709.1 - 0.073 12.7 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Diaphanous FH3 Domain XPC-binding PF09280.11 CDJ87709.1 - 0.11 12.2 2.3 0.46 10.2 0.4 3.1 4 0 0 4 4 4 0 XPC-binding domain FAD_binding_1 PF00667.20 CDJ87709.1 - 0.14 11.7 0.7 0.96 9.0 0.0 2.2 2 1 0 2 2 2 0 FAD binding domain Hormone_6 PF00236.18 CDJ87709.1 - 0.16 11.9 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Glycoprotein hormone V-ATPase_H_C PF11698.8 CDJ87709.1 - 0.17 12.0 0.2 9.8 6.3 0.0 3.3 4 0 0 4 4 4 0 V-ATPase subunit H Coat_F PF07875.12 CDJ87709.1 - 0.26 11.5 1.0 2.7 8.3 0.1 2.6 2 0 0 2 2 2 0 Coat F domain TetR_C_11 PF16859.5 CDJ87709.1 - 0.71 10.2 4.1 0.88 9.9 0.1 3.1 3 1 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DUF3337 PF11816.8 CDJ87710.1 - 1.6e-38 132.2 0.1 3.2e-38 131.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 CDJ87710.1 - 5e-28 96.8 6.3 1.1e-05 26.0 0.0 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ87710.1 - 1.2e-06 28.7 1.3 0.084 13.2 0.0 4.1 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ87710.1 - 0.00061 18.9 1.3 0.16 10.9 0.0 2.4 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CDJ87710.1 - 0.027 13.1 6.6 0.56 8.8 0.1 3.0 1 1 2 3 3 3 0 Nucleoporin Nup120/160 PROCN PF08083.11 CDJ87711.1 - 5.3e-233 773.0 7.8 5.3e-233 773.0 7.8 2.1 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 CDJ87711.1 - 1.1e-126 421.0 1.3 2.1e-126 420.2 1.3 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 CDJ87711.1 - 1.8e-89 297.8 2.0 5.2e-89 296.2 2.0 1.9 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 CDJ87711.1 - 9.4e-88 291.9 4.7 9.4e-88 291.9 4.7 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 CDJ87711.1 - 2.4e-73 244.5 0.1 5.2e-73 243.4 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 CDJ87711.1 - 3e-50 169.2 0.1 8.4e-50 167.8 0.1 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 CDJ87711.1 - 9.8e-47 157.2 1.2 1.7e-46 156.5 0.3 2.0 2 0 0 2 2 2 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 CDJ87711.1 - 5e-07 29.7 0.0 1.5e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Peptidase_M18 PF02127.15 CDJ87712.1 - 6.1e-173 575.6 0.0 8.1e-173 575.1 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) BTB PF00651.31 CDJ87712.1 - 3.4e-26 91.6 0.0 6.9e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Peptidase_M42 PF05343.14 CDJ87712.1 - 6.7e-09 35.2 2.3 9.3e-07 28.1 0.2 2.9 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase Prefoldin PF02996.17 CDJ87712.1 - 0.35 10.8 1.9 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Prefoldin subunit Mito_carr PF00153.27 CDJ87713.1 - 2.9e-57 190.6 2.4 1.8e-18 66.2 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein Utp11 PF03998.13 CDJ87713.1 - 1.5e-52 179.0 24.4 2.8e-52 178.1 24.4 1.4 1 0 0 1 1 1 1 Utp11 protein E2F_TDP PF02319.20 CDJ87713.1 - 1.1e-15 57.4 0.2 4.9e-15 55.3 0.2 2.2 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 CDJ87713.1 - 3.9e-07 30.4 0.7 3.9e-07 30.4 0.7 1.9 2 0 0 2 2 2 1 E2F transcription factor CC-MB domain DUF4407 PF14362.6 CDJ87713.1 - 2 7.7 6.0 0.12 11.7 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RhoGEF PF00621.20 CDJ87714.1 - 6.6e-11 42.8 0.3 1.2e-10 42.0 0.3 1.3 1 0 0 1 1 1 1 RhoGEF domain BRCT PF00533.26 CDJ87714.1 - 4.5e-06 26.9 0.0 0.051 14.0 0.0 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CDJ87714.1 - 0.0048 16.8 0.0 4.3 7.4 0.0 2.5 2 0 0 2 2 2 2 twin BRCT domain BRCT_2 PF16589.5 CDJ87714.1 - 0.097 13.1 0.0 1.1 9.8 0.0 2.4 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain Glyco_tran_WecB PF03808.13 CDJ87714.1 - 0.11 12.5 0.0 2.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family PAXNEB PF05625.11 CDJ87715.1 - 8.9e-47 160.0 0.0 1.6e-46 159.2 0.0 1.3 1 1 0 1 1 1 1 PAXNEB protein Ras PF00071.22 CDJ87716.1 - 7.1e-19 68.0 0.0 9.4e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ87716.1 - 1.8e-06 28.1 0.0 2.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ87716.1 - 4.9e-05 22.8 0.0 7.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ87716.1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.6 CDJ87716.1 - 0.0099 15.9 0.0 0.04 13.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ87716.1 - 0.022 15.1 0.0 0.043 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain DUF2677 PF10838.8 CDJ87716.1 - 0.04 13.9 0.0 0.081 12.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2677) CRM1_repeat_2 PF18784.1 CDJ87716.1 - 0.17 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 PDZ PF00595.24 CDJ87718.1 - 1.4e-36 124.7 4.3 4.8e-12 46.1 0.1 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 CDJ87718.1 - 2.7e-23 81.6 2.1 2.4e-09 36.9 0.1 3.6 3 0 0 3 3 3 3 PDZ domain FERM_M PF00373.18 CDJ87718.1 - 7.7e-21 74.7 0.1 2.1e-20 73.3 0.1 1.7 1 0 0 1 1 1 1 FERM central domain PDZ_2 PF13180.6 CDJ87718.1 - 1.1e-15 57.7 3.0 0.00035 20.8 0.1 3.7 3 0 0 3 3 3 3 PDZ domain FERM_N PF09379.10 CDJ87718.1 - 7.2e-15 54.7 0.1 1.5e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 FERM N-terminal domain FERM_C PF09380.10 CDJ87718.1 - 8.7e-13 48.5 1.3 1.4e-12 47.8 0.3 1.8 2 0 0 2 2 2 1 FERM C-terminal PH-like domain PDZ_4 PF17816.1 CDJ87718.1 - 0.005 17.2 0.0 9.8 6.6 0.0 3.7 3 1 1 4 4 4 2 PDZ domain Tricorn_PDZ PF14685.6 CDJ87718.1 - 0.0063 16.5 2.9 1 9.4 0.1 3.8 4 0 0 4 4 4 1 Tricorn protease PDZ domain 7TM_GPCR_Srbc PF10316.9 CDJ87719.1 - 6e-15 55.5 13.2 9e-15 54.9 13.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7tm_1 PF00001.21 CDJ87719.1 - 5.3e-10 39.1 0.0 7.3e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ87719.1 - 0.00043 19.7 10.6 0.0011 18.4 10.6 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx PDZ_6 PF17820.1 CDJ87719.1 - 0.0019 18.0 0.0 0.017 15.0 0.0 2.4 2 0 0 2 2 2 1 PDZ domain 7TM_GPCR_Srx PF10328.9 CDJ87719.1 - 0.1 12.2 8.6 0.19 11.3 8.6 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx PDZ PF00595.24 CDJ87719.1 - 0.14 12.5 0.0 5 7.5 0.0 2.6 2 0 0 2 2 2 0 PDZ domain HTH_48 PF17906.1 CDJ87720.1 - 7.6e-09 35.6 0.0 1.4e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase MTABC_N PF16185.5 CDJ87720.1 - 0.0013 18.3 0.3 0.002 17.7 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region HTH_5 PF01022.20 CDJ87720.1 - 0.023 14.5 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family 7TMR-DISM_7TM PF07695.11 CDJ87720.1 - 0.06 13.2 5.5 0.097 12.6 5.5 1.4 1 0 0 1 1 1 0 7TM diverse intracellular signalling HTH_Tnp_Tc3_2 PF01498.18 CDJ87720.1 - 0.11 12.7 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Transposase HTH_11 PF08279.12 CDJ87720.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 HTH domain HTH_50 PF18024.1 CDJ87720.1 - 0.15 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Ost5 PF05251.12 CDJ87720.1 - 0.87 9.9 6.2 0.77 10.1 0.4 2.4 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 RT_RNaseH PF17917.1 CDJ87721.1 - 2.7e-08 34.0 0.0 6.2e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ87721.1 - 4.8e-08 33.0 0.1 8.6e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain NTP_transferase PF00483.23 CDJ87722.1 - 2e-27 96.4 0.0 2.7e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CDJ87722.1 - 4.4e-09 35.7 8.9 6.6e-06 25.7 0.5 4.2 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CDJ87722.1 - 1.2e-07 32.2 0.0 1.9e-07 31.6 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 CDJ87722.1 - 0.035 13.9 0.8 0.43 10.4 0.2 2.8 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase DEAD PF00270.29 CDJ87723.1 - 2e-39 135.2 1.4 6.4e-39 133.5 0.3 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ87723.1 - 2e-09 37.8 0.7 1.5e-08 35.0 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ87723.1 - 1.4e-07 31.6 0.1 3.2e-07 30.5 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CDJ87723.1 - 0.0018 18.6 0.2 0.0031 17.9 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ87723.1 - 0.0023 17.7 0.1 0.0043 16.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 CDJ87723.1 - 0.013 15.0 0.1 0.025 14.1 0.1 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain PhoH PF02562.16 CDJ87723.1 - 0.076 12.5 0.3 0.17 11.3 0.1 1.6 2 0 0 2 2 2 0 PhoH-like protein Helicase_RecD PF05127.14 CDJ87723.1 - 0.078 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 CDJ87723.1 - 0.087 13.1 0.2 0.33 11.2 0.2 2.0 1 1 0 1 1 1 0 AAA domain Nup54 PF13874.6 CDJ87725.1 - 0.035 14.2 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 7tm_1 PF00001.21 CDJ87726.1 - 5.3e-15 55.5 4.7 9.2e-15 54.7 4.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) BIV_Env PF05858.12 CDJ87726.1 - 0.0085 14.3 1.2 0.012 13.9 1.2 1.1 1 0 0 1 1 1 1 Bovine immunodeficiency virus surface protein (SU) 7TM_GPCR_Srsx PF10320.9 CDJ87726.1 - 0.037 13.4 5.3 0.25 10.7 5.2 2.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx TMEM154 PF15102.6 CDJ87726.1 - 0.23 11.4 1.5 0.45 10.4 1.5 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF4642 PF15484.6 CDJ87727.1 - 5.9e-06 26.6 3.9 2.7 8.2 0.0 5.8 3 1 1 6 6 6 3 Domain of unknown function (DUF4642) Prefoldin_3 PF13758.6 CDJ87727.1 - 0.0012 18.8 0.1 72 3.5 0.0 5.2 4 2 2 6 6 6 0 Prefoldin subunit Bacteroid_pep PF14406.6 CDJ87727.1 - 0.23 11.8 10.4 31 5.0 0.0 7.2 10 1 1 11 11 11 0 Ribosomally synthesized peptide in Bacteroidetes PAN_1 PF00024.26 CDJ87728.1 - 1.1e-20 73.4 13.7 1.9e-07 31.0 1.1 3.6 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.6 CDJ87728.1 - 2.9e-05 23.9 11.1 0.0042 17.0 0.2 3.8 3 0 0 3 3 3 2 PAN domain Asp PF00026.23 CDJ87729.1 - 8.7e-116 386.7 0.0 1e-115 386.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ87729.1 - 3e-10 40.6 0.1 1e-08 35.6 0.1 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ87729.1 - 6.9e-06 25.9 0.0 1.8e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal ArfGap PF01412.18 CDJ87729.1 - 0.02 15.0 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf A1_Propeptide PF07966.12 CDJ87729.1 - 0.024 14.5 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 A1 Propeptide HEAT PF02985.22 CDJ87731.1 - 3.3e-12 45.6 0.0 0.03 14.6 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.6 CDJ87731.1 - 3.3e-06 27.5 2.4 0.018 15.5 0.2 4.4 5 1 1 6 6 6 2 HEAT-like repeat Pkinase PF00069.25 CDJ87731.1 - 5e-06 26.1 0.0 8.7e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT_2 PF13646.6 CDJ87731.1 - 6.8e-06 26.4 0.0 0.0074 16.7 0.0 3.1 1 1 2 3 3 3 2 HEAT repeats Pkinase_Tyr PF07714.17 CDJ87731.1 - 0.00025 20.4 0.0 0.091 12.0 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Cnd1 PF12717.7 CDJ87731.1 - 0.0013 18.8 0.0 0.74 9.8 0.0 2.6 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CDJ87731.1 - 0.043 12.4 0.0 0.47 9.0 0.0 2.0 1 1 0 1 1 1 0 Adaptin N terminal region Cohesin_HEAT PF12765.7 CDJ87731.1 - 0.15 12.4 0.1 0.58 10.5 0.0 2.0 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion RRM_1 PF00076.22 CDJ87732.1 - 2.6e-18 65.6 0.0 5e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ87732.1 - 1.4e-05 25.1 0.1 5.9e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 CDJ87732.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Orthopox_A36R PF05950.11 CDJ87732.1 - 0.03 14.5 0.1 0.057 13.6 0.1 1.4 1 0 0 1 1 1 0 Orthopoxvirus A36R protein CC190 PF15768.5 CDJ87732.1 - 0.11 12.6 6.5 0.18 11.9 6.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 MSP1a PF11670.8 CDJ87734.1 - 0.073 12.4 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) Consortin_C PF15281.6 CDJ87734.1 - 0.12 12.4 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Consortin C-terminus LRR19-TM PF15176.6 CDJ87734.1 - 0.4 10.7 2.1 1.2 9.2 2.1 1.8 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain SNARE PF05739.19 CDJ87734.1 - 0.48 10.5 2.0 0.75 9.8 0.7 1.9 2 0 0 2 2 2 0 SNARE domain DUF3827 PF12877.7 CDJ87735.1 - 0.037 12.4 1.0 0.043 12.2 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Dsh_C PF12316.8 CDJ87735.1 - 0.82 10.0 5.9 1 9.7 5.9 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Eapp_C PF10238.9 CDJ87735.1 - 2.1 8.4 6.3 3.3 7.8 6.3 1.4 1 1 0 1 1 1 0 E2F-associated phosphoprotein ATG22 PF11700.8 CDJ87736.1 - 0.028 13.1 0.0 0.03 13.0 0.0 1.2 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Mito_fiss_reg PF05308.11 CDJ87736.1 - 0.33 11.0 7.4 0.43 10.6 7.4 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Orf78 PF06024.12 CDJ87737.1 - 0.0074 16.6 0.5 0.02 15.2 0.5 1.6 1 1 0 1 1 1 1 Orf78 (ac78) OATP PF03137.20 CDJ87737.1 - 0.062 11.6 0.0 0.08 11.2 0.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family TMEM100 PF16311.5 CDJ87737.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 100 Gemini_mov PF01708.16 CDJ87737.1 - 0.45 10.3 1.7 0.73 9.6 1.7 1.4 1 1 0 1 1 1 0 Geminivirus putative movement protein SWIRM-assoc_2 PF16496.5 CDJ87737.1 - 2 7.2 6.7 2.5 6.9 6.7 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal CrgA PF06781.12 CDJ87737.1 - 8.9 6.5 5.8 31 4.7 5.8 1.8 1 1 0 1 1 1 0 Cell division protein CrgA Activin_recp PF01064.23 CDJ87738.1 - 0.2 12.8 7.7 0.29 12.2 7.7 1.3 1 0 0 1 1 1 0 Activin types I and II receptor domain Toxin_TOLIP PF00087.21 CDJ87738.1 - 1.7 9.0 11.1 2.5 8.4 11.1 1.3 1 0 0 1 1 1 0 Snake toxin and toxin-like protein Sec1 PF00995.23 CDJ87739.1 - 5.7e-121 405.5 0.1 6.5e-121 405.4 0.1 1.0 1 0 0 1 1 1 1 Sec1 family T3SchapCesA PF11439.8 CDJ87739.1 - 0.085 13.0 0.1 1.2 9.4 0.1 2.6 3 0 0 3 3 3 0 Type III secretion system filament chaperone CesA DUF2785 PF10978.8 CDJ87739.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) JmjC PF02373.22 CDJ87740.1 - 5.1e-17 62.4 0.2 9.3e-17 61.5 0.2 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CDJ87740.1 - 9.8e-14 51.7 0.3 9.8e-14 51.7 0.3 2.3 2 1 0 2 2 2 1 Cupin-like domain Mpp10 PF04006.12 CDJ87740.1 - 0.00083 17.9 10.8 0.0013 17.3 10.8 1.2 1 0 0 1 1 1 1 Mpp10 protein Nop14 PF04147.12 CDJ87740.1 - 0.2 9.8 19.4 0.31 9.2 19.4 1.2 1 0 0 1 1 1 0 Nop14-like family Na_trans_assoc PF06512.13 CDJ87740.1 - 0.63 10.3 13.4 1.2 9.3 13.4 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated PPP4R2 PF09184.11 CDJ87740.1 - 1.1 8.7 22.6 1.8 8.1 22.6 1.2 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 CDJ87740.1 - 1.5 8.1 25.6 2.1 7.6 25.6 1.1 1 0 0 1 1 1 0 BUD22 LAP1C PF05609.12 CDJ87740.1 - 5.2 6.1 11.6 7.2 5.6 11.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC45 PF02724.14 CDJ87740.1 - 6.9 4.8 17.2 66 1.6 19.0 1.6 2 0 0 2 2 2 0 CDC45-like protein JmjC PF02373.22 CDJ87741.1 - 6.3e-20 71.7 0.5 1.4e-19 70.6 0.3 1.7 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CDJ87741.1 - 1.1e-18 67.9 0.3 3.2e-17 63.1 0.3 2.2 1 1 0 1 1 1 1 Cupin-like domain SIR4_SID PF16991.5 CDJ87741.1 - 1.1 9.3 4.8 12 5.9 0.0 2.6 2 0 0 2 2 2 0 Sir4 SID domain 7TM_GPCR_Srw PF10324.9 CDJ87742.1 - 9.4e-12 44.8 16.1 1.2e-11 44.5 16.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 CDJ87742.1 - 2.6e-11 43.4 13.7 3.6e-11 42.9 13.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CDJ87742.1 - 0.0003 20.5 3.0 0.0003 20.5 3.0 2.5 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.15 CDJ87742.1 - 0.26 11.3 6.5 0.057 13.4 1.1 2.2 1 1 1 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa MCM PF00493.23 CDJ87744.1 - 2.7e-100 334.1 0.0 9.9e-100 332.2 0.0 1.9 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 CDJ87744.1 - 4.5e-34 117.0 0.3 8.6e-34 116.1 0.3 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CDJ87744.1 - 1.2e-28 99.4 1.2 2.9e-28 98.1 1.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM2_N PF12619.8 CDJ87744.1 - 9e-14 52.0 24.3 9e-14 52.0 24.3 2.4 3 1 0 3 3 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 CDJ87744.1 - 2.5e-13 50.5 0.9 7e-13 49.1 0.1 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 CDJ87744.1 - 2.1e-08 33.8 0.0 5.6e-07 29.1 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CDJ87744.1 - 3.1e-06 27.3 0.0 7.3e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CDJ87744.1 - 4.9e-05 23.2 0.0 0.00025 20.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cullin PF00888.22 CDJ87744.1 - 0.0027 16.4 0.6 0.0049 15.5 0.6 1.3 1 0 0 1 1 1 1 Cullin family AAA PF00004.29 CDJ87744.1 - 0.0035 17.8 0.1 0.024 15.0 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 CDJ87744.1 - 0.0036 17.1 0.2 0.024 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA lid domain Sigma54_activat PF00158.26 CDJ87744.1 - 0.01 15.5 0.0 0.37 10.5 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF648 PF04890.13 CDJ87744.1 - 0.036 13.8 0.6 0.061 13.1 0.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF648) Zn-ribbon_8 PF09723.10 CDJ87744.1 - 0.048 13.8 0.9 0.14 12.3 0.9 1.8 1 0 0 1 1 1 0 Zinc ribbon domain DUF3372 PF11852.8 CDJ87744.1 - 0.15 11.6 0.5 3.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3372) Mer2 PF09074.10 CDJ87744.1 - 1.8 8.3 6.3 0.68 9.7 2.2 2.3 2 0 0 2 2 2 0 Mer2 UDPGT PF00201.18 CDJ87745.1 - 1.3e-61 208.9 0.0 1.9e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ87745.1 - 5.9e-10 39.4 0.0 1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF1980 PF09323.10 CDJ87745.1 - 0.045 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Glyco_trans_1_3 PF13528.6 CDJ87745.1 - 0.061 12.6 0.1 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 1 F-box PF00646.33 CDJ87746.1 - 0.00011 22.0 0.6 0.00011 22.0 0.6 2.2 2 0 0 2 2 2 1 F-box domain Luteo_PO PF04662.13 CDJ87746.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Luteovirus P0 protein Patched PF02460.18 CDJ87747.1 - 1.2e-27 96.4 3.7 1.3e-27 96.3 3.7 1.0 1 0 0 1 1 1 1 Patched family NOB1_Zn_bind PF08772.11 CDJ87751.1 - 0.016 15.3 0.5 0.13 12.4 0.5 2.3 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.7 CDJ87751.1 - 0.024 14.6 0.1 0.089 12.8 0.1 2.0 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2_4 PF13894.6 CDJ87752.1 - 0.0016 19.1 24.7 0.039 14.8 2.1 4.9 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CDJ87752.1 - 0.17 12.5 7.5 0.5 11.0 2.4 2.6 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats FOXP-CC PF16159.5 CDJ87752.1 - 0.45 11.2 4.9 14 6.4 0.0 3.0 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 CDJ87752.1 - 0.78 10.3 0.1 0.78 10.3 0.1 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CDJ87752.1 - 1.1 9.6 4.2 3.5 8.0 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CDJ87753.1 - 0.001 19.3 16.0 0.17 12.2 1.0 4.6 4 0 0 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 CDJ87753.1 - 0.0035 17.1 0.5 0.0035 17.1 0.5 3.1 4 0 0 4 4 4 1 zinc-finger C2H2-type zf-C2H2 PF00096.26 CDJ87753.1 - 0.1 13.1 0.5 0.1 13.1 0.5 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 CDJ87753.1 - 0.13 12.9 9.1 0.074 13.7 2.6 2.9 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 CDJ87753.1 - 0.26 12.2 0.3 0.26 12.2 0.3 5.5 5 0 0 5 5 5 0 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 CDJ87753.1 - 5 7.7 6.5 1.6 9.2 0.1 3.1 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain RVT_1 PF00078.27 CDJ87754.1 - 1.9e-15 57.0 0.0 3.4e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ShK PF01549.24 CDJ87755.1 - 3.4e-05 24.3 21.4 0.00037 21.0 5.1 2.9 2 1 0 2 2 2 2 ShK domain-like ShK PF01549.24 CDJ87756.1 - 5.1e-05 23.7 24.2 0.0015 19.0 7.2 3.4 2 1 1 3 3 3 2 ShK domain-like DUF1241 PF06840.11 CDJ87757.1 - 7.4e-51 171.7 0.2 1.1e-50 171.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Metallophos_2 PF12850.7 CDJ87757.1 - 0.002 18.3 0.1 0.035 14.3 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain BLOC1_2 PF10046.9 CDJ87757.1 - 0.004 17.4 0.1 0.012 15.9 0.1 1.8 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Focal_AT PF03623.13 CDJ87757.1 - 0.0076 16.2 0.8 0.017 15.1 0.7 1.7 1 1 0 1 1 1 1 Focal adhesion targeting region Ion_trans_2 PF07885.16 CDJ87759.1 - 2.7e-09 36.9 2.9 9.8e-09 35.1 0.4 2.3 2 0 0 2 2 2 1 Ion channel DDE_3 PF13358.6 CDJ87761.1 - 0.0045 16.8 0.3 0.006 16.3 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease TTR-52 PF01060.23 CDJ87763.1 - 1.2e-14 54.7 0.0 1.6e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Transthyretin-like family DnaJ PF00226.31 CDJ87765.1 - 3.8e-25 87.8 2.1 5.8e-25 87.2 2.1 1.3 1 0 0 1 1 1 1 DnaJ domain Corona_S2 PF01601.16 CDJ87765.1 - 4.4e-05 22.2 3.0 5.2e-05 21.9 3.0 1.0 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein RD3 PF14473.6 CDJ87766.1 - 3.5e-24 85.1 1.5 4.6e-24 84.7 1.5 1.1 1 0 0 1 1 1 1 RD3 protein DUF4746 PF15928.5 CDJ87767.1 - 1.2 8.5 10.3 1.6 8.1 10.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop14 PF04147.12 CDJ87767.1 - 1.5 6.9 26.2 1.9 6.6 26.2 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CDJ87767.1 - 4.2 5.5 17.1 4.7 5.4 17.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 CDJ87767.1 - 5.1 6.4 22.1 6.9 6.0 22.1 1.2 1 0 0 1 1 1 0 SDA1 ENTH PF01417.20 CDJ87768.1 - 7.1e-29 100.4 0.0 8.3e-29 100.2 0.0 1.0 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 CDJ87768.1 - 0.00015 20.9 0.0 0.00017 20.7 0.0 1.0 1 0 0 1 1 1 1 ANTH domain Ig_3 PF13927.6 CDJ87769.1 - 6.1e-28 97.2 0.0 8.4e-13 48.7 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 CDJ87769.1 - 5.5e-27 93.7 0.0 7.3e-14 51.6 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 CDJ87769.1 - 1.4e-23 83.0 0.0 5.1e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 CDJ87769.1 - 1.8e-14 53.7 0.1 8.1e-07 29.1 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 CDJ87769.1 - 1.4e-12 47.7 0.2 0.01 16.0 0.0 4.1 3 1 0 3 3 3 3 Immunoglobulin V-set domain Ig_5 PF16681.5 CDJ87769.1 - 3.1e-06 27.5 0.0 0.62 10.5 0.0 3.3 3 1 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 CDJ87769.1 - 7.1e-06 25.5 0.0 0.12 11.9 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 CDJ87769.1 - 7.5e-06 25.9 0.0 0.057 13.5 0.0 2.4 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 CDJ87769.1 - 0.0019 18.4 0.1 0.66 10.3 0.1 3.1 2 2 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 CDJ87769.1 - 0.0082 16.2 0.0 1.5 8.9 0.0 2.6 2 1 0 2 2 2 1 C17orf99 Ig domain C1-set PF07654.15 CDJ87769.1 - 0.011 16.1 0.0 0.65 10.4 0.0 2.5 2 1 0 2 2 2 0 Immunoglobulin C1-set domain BiPBP_C PF06832.12 CDJ87769.1 - 0.15 12.2 0.0 3.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family THOC2_N PF16134.5 CDJ87770.1 - 6.6e-66 223.3 0.0 2e-38 132.5 0.3 2.8 1 1 1 2 2 2 2 THO complex subunit 2 N-terminus Thoc2 PF11732.8 CDJ87770.1 - 1.1e-29 102.3 0.1 2.6e-29 101.1 0.1 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit DUF229 PF02995.17 CDJ87771.1 - 5.8e-77 259.4 1.0 7.4e-77 259.0 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 CDJ87771.1 - 0.044 13.2 0.1 0.21 10.9 0.0 1.9 1 1 0 2 2 2 0 Sulfatase Pkinase PF00069.25 CDJ87772.1 - 5.5e-59 199.7 0.0 7.9e-59 199.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ87772.1 - 1.2e-24 87.0 0.0 2.8e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Shisa PF13908.6 CDJ87773.1 - 0.46 10.7 5.8 0.1 12.9 1.3 1.9 1 1 0 2 2 2 0 Wnt and FGF inhibitory regulator AA_permease_2 PF13520.6 CDJ87774.1 - 4.6e-56 190.5 41.3 5.8e-56 190.1 41.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CDJ87774.1 - 6.1e-28 97.6 38.0 1.4e-27 96.5 38.0 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CDJ87775.1 - 1.3e-62 212.1 38.1 1.5e-62 211.8 38.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CDJ87775.1 - 1.5e-31 109.5 35.2 2.4e-31 108.9 35.2 1.2 1 0 0 1 1 1 1 Amino acid permease DUF2207 PF09972.9 CDJ87775.1 - 9 4.9 0.0 9 4.9 0.0 3.0 3 1 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF410 PF04190.13 CDJ87776.1 - 5.9e-51 173.7 0.5 7.3e-51 173.4 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) PAH PF02671.21 CDJ87776.1 - 0.08 13.1 0.6 11 6.2 0.1 3.3 2 1 1 3 3 3 0 Paired amphipathic helix repeat TPR_2 PF07719.17 CDJ87776.1 - 0.21 11.8 4.0 22 5.5 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat FAD_binding_1 PF00667.20 CDJ87777.1 - 6e-28 97.9 0.0 1.1e-27 97.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CDJ87777.1 - 6.8e-28 97.7 0.0 1.3e-27 96.7 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CDJ87777.1 - 3.2e-09 37.4 0.0 6.3e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 CDJ87777.1 - 0.058 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain AA_permease_2 PF13520.6 CDJ87778.1 - 2.3e-24 86.0 15.5 4e-24 85.2 15.5 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CDJ87778.1 - 3.9e-15 55.4 12.4 5.1e-15 55.0 12.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2070 PF09843.9 CDJ87778.1 - 0.93 7.7 14.1 1.2 7.4 14.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TctB PF07331.11 CDJ87778.1 - 1.6 9.0 17.3 0.12 12.6 8.7 2.4 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family TPR_1 PF00515.28 CDJ87779.1 - 1.2e-07 31.3 0.2 0.0052 16.5 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ87779.1 - 0.0058 16.6 6.6 1.7 8.9 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF2267 PF10025.9 CDJ87779.1 - 0.025 14.9 1.7 0.028 14.7 0.2 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) TPR_17 PF13431.6 CDJ87779.1 - 0.14 12.6 0.3 7.2 7.2 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat ASC PF00858.24 CDJ87780.1 - 1.6e-19 70.2 2.3 1.8e-19 70.1 2.3 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Mucin PF01456.17 CDJ87781.1 - 0.0036 17.3 24.8 0.0036 17.3 24.8 2.3 2 0 0 2 2 2 1 Mucin-like glycoprotein AJAP1_PANP_C PF15298.6 CDJ87781.1 - 0.088 13.0 16.3 0.62 10.2 12.9 2.5 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Sporozoite_P67 PF05642.11 CDJ87781.1 - 0.27 9.3 10.5 0.79 7.7 10.4 1.6 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Dicty_REP PF05086.12 CDJ87781.1 - 4.1 5.3 12.0 5.9 4.7 12.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3270 PF11674.8 CDJ87782.1 - 0.0065 16.6 0.4 0.016 15.4 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3270) CDK2AP PF09806.9 CDJ87782.1 - 0.036 14.1 0.0 0.075 13.1 0.0 1.5 1 1 1 2 2 2 0 Cyclin-dependent kinase 2-associated protein Connexin PF00029.19 CDJ87782.1 - 0.18 11.5 0.2 0.25 11.1 0.2 1.2 1 0 0 1 1 1 0 Connexin DUF5427 PF10310.9 CDJ87782.1 - 0.33 9.9 8.2 0.4 9.6 8.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) FH2 PF02181.23 CDJ87784.1 - 1.3e-46 159.4 3.4 1.8e-46 158.9 3.4 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 CDJ87784.1 - 0.092 12.3 1.9 0.099 12.2 0.3 1.8 2 0 0 2 2 2 0 Diaphanous FH3 Domain Dimer_Tnp_hAT PF05699.14 CDJ87785.1 - 0.0034 17.2 0.0 0.0094 15.7 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF2201_N PF13203.6 CDJ87786.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF5481 PF17578.2 CDJ87787.1 - 0.52 10.7 3.5 3.7 8.0 0.6 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5481) Asp-B-Hydro_N PF05279.11 CDJ87787.1 - 2.1 8.4 18.5 2.8 7.9 18.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region BTG PF07742.12 CDJ87788.1 - 1.9e-25 88.9 0.0 3.4e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 BTG family DUF148 PF02520.17 CDJ87789.1 - 8.1e-14 51.7 3.2 1.1e-13 51.2 3.2 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF148 OmpH PF03938.14 CDJ87789.1 - 0.041 14.2 2.2 0.058 13.7 2.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4201 PF13870.6 CDJ87789.1 - 0.055 13.2 1.0 0.085 12.6 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) TipAS PF07739.13 CDJ87789.1 - 0.059 13.9 1.5 0.091 13.3 1.5 1.2 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain DUF938 PF06080.12 CDJ87789.1 - 0.071 12.9 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF938) HAUS5 PF14817.6 CDJ87789.1 - 0.13 11.0 0.1 0.16 10.7 0.1 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 DLP_helical PF18709.1 CDJ87789.1 - 0.23 10.6 2.6 0.32 10.2 2.6 1.1 1 0 0 1 1 1 0 Dynamin-like helical domain DUF1798 PF08807.10 CDJ87790.1 - 0.025 14.7 0.9 0.076 13.2 0.3 1.9 2 0 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) B2 PF11473.8 CDJ87790.1 - 0.07 12.9 0.6 0.58 10.0 0.0 2.6 2 1 0 2 2 2 0 RNA binding protein B2 DUF1878 PF08963.10 CDJ87790.1 - 0.19 12.2 0.5 0.43 11.1 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1878) DEAD PF00270.29 CDJ87791.1 - 1e-48 165.4 0.0 8e-48 162.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase SCVP PF17619.2 CDJ87791.1 - 2.7e-39 133.9 4.7 1.7e-19 70.5 1.1 3.0 2 0 0 2 2 2 2 Secreted clade V proteins Helicase_C PF00271.31 CDJ87791.1 - 3.4e-25 88.5 0.1 1.6e-24 86.4 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CDJ87791.1 - 0.00088 18.5 0.0 0.002 17.4 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF108 PF01958.18 CDJ87791.1 - 0.0047 17.3 0.5 0.33 11.4 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function DUF108 CLN3 PF02487.17 CDJ87791.1 - 0.032 13.3 0.3 0.063 12.3 0.2 1.6 1 1 0 1 1 1 0 CLN3 protein Sec7 PF01369.20 CDJ87792.1 - 5.1e-64 215.3 0.1 8.4e-64 214.6 0.1 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CDJ87792.1 - 8.3e-28 97.3 3.6 8.3e-28 97.3 3.6 2.4 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Peptidase_S24 PF00717.23 CDJ87792.1 - 2.9e-09 36.8 0.0 6.5e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like DCB PF16213.5 CDJ87792.1 - 9.5e-07 28.6 0.0 2.7e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Peptidase_S26 PF10502.9 CDJ87792.1 - 0.00068 19.4 0.0 0.0023 17.8 0.0 1.9 2 0 0 2 2 2 1 Signal peptidase, peptidase S26 DUF1981 PF09324.10 CDJ87792.1 - 0.078 12.8 0.0 6.5 6.7 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1981) EF-hand_7 PF13499.6 CDJ87793.1 - 5.9e-32 109.9 19.6 1.2e-08 35.3 0.3 4.6 1 1 5 6 6 6 6 EF-hand domain pair EF-hand_1 PF00036.32 CDJ87793.1 - 8.8e-32 106.3 2.6 0.0001 21.6 0.0 6.2 6 0 0 6 6 6 6 EF hand EF-hand_6 PF13405.6 CDJ87793.1 - 4.5e-28 94.8 4.8 0.00088 19.0 0.0 6.2 6 0 0 6 6 6 6 EF-hand domain EF-hand_5 PF13202.6 CDJ87793.1 - 4.9e-26 89.0 5.3 0.00018 20.8 0.0 6.5 6 0 0 6 6 6 5 EF hand EF-hand_8 PF13833.6 CDJ87793.1 - 2e-16 59.6 9.8 0.024 14.5 0.1 6.1 3 3 3 6 6 6 6 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ87793.1 - 3.8e-10 40.1 2.3 0.0068 16.7 0.8 3.9 1 1 3 4 4 4 4 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 CDJ87793.1 - 1.1e-05 25.2 1.5 7 6.6 0.0 4.8 5 1 0 5 5 5 2 EF hand EF-hand_4 PF12763.7 CDJ87793.1 - 2.5e-05 24.1 4.2 0.22 11.5 0.1 4.3 2 1 1 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 CDJ87793.1 - 0.005 17.0 11.3 0.27 11.4 2.2 4.2 3 2 1 4 4 4 2 Dockerin type I domain Cnl2_NKP2 PF09447.10 CDJ87793.1 - 0.011 15.9 0.1 0.053 13.7 0.0 2.2 2 0 0 2 2 2 0 Cnl2/NKP2 family protein FG-GAP PF01839.23 CDJ87793.1 - 0.018 15.2 6.4 0.12 12.5 0.9 3.0 3 0 0 3 3 3 0 FG-GAP repeat PMBR PF09373.10 CDJ87793.1 - 0.019 15.1 1.7 7.1 7.0 0.1 4.7 4 1 1 5 5 5 0 Pseudomurein-binding repeat VCBS PF13517.6 CDJ87793.1 - 0.076 13.6 4.1 2.8 8.6 0.2 3.2 3 1 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella WW PF00397.26 CDJ87794.1 - 1.2e-06 28.5 1.9 3e-06 27.2 1.9 1.8 1 0 0 1 1 1 1 WW domain Ion_trans_2 PF07885.16 CDJ87795.1 - 7e-30 102.8 16.3 9.9e-18 63.9 2.6 2.5 2 0 0 2 2 2 2 Ion channel IRK PF01007.20 CDJ87795.1 - 0.0092 15.8 2.8 1.8 8.3 0.2 2.8 2 1 0 2 2 2 2 Inward rectifier potassium channel transmembrane domain Lig_chan PF00060.26 CDJ87795.1 - 0.17 11.7 0.3 0.55 10.1 0.3 1.8 1 1 0 1 1 1 0 Ligand-gated ion channel DUF1853 PF08907.11 CDJ87796.1 - 0.039 13.7 0.4 0.058 13.1 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1853) Barwin PF00967.17 CDJ87797.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 Barwin family Rotamase_3 PF13616.6 CDJ87797.1 - 0.15 12.6 0.0 0.25 11.9 0.0 1.3 1 0 0 1 1 1 0 PPIC-type PPIASE domain BTB PF00651.31 CDJ87798.1 - 7.8e-18 64.7 0.4 1.5e-17 63.8 0.2 1.6 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 CDJ87798.1 - 7.5e-05 22.8 0.0 0.00051 20.1 0.0 2.3 1 1 0 1 1 1 1 BTB And C-terminal Kelch Filamin PF00630.19 CDJ87799.1 - 3.8e-17 63.0 1.0 1.7e-08 35.2 0.1 4.1 3 1 0 4 4 4 2 Filamin/ABP280 repeat PapC_N PF13954.6 CDJ87799.1 - 0.014 15.4 0.0 0.3 11.1 0.0 2.3 2 0 0 2 2 2 0 PapC N-terminal domain DUF5373 PF17343.2 CDJ87800.1 - 2 8.2 9.8 0.35 10.7 4.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5373) AI-2E_transport PF01594.16 CDJ87800.1 - 2.2 7.4 23.8 9.4 5.3 23.8 1.9 1 1 0 1 1 1 0 AI-2E family transporter DB PF01682.19 CDJ87803.1 - 1.9e-10 40.9 14.4 2.8e-10 40.4 14.4 1.2 1 0 0 1 1 1 1 DB module V-set PF07686.17 CDJ87803.1 - 0.0089 16.2 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 CDJ87803.1 - 0.099 13.3 0.0 0.23 12.1 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.6 CDJ87804.1 - 2.6e-25 88.8 0.0 5.5e-11 42.9 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 CDJ87804.1 - 8e-21 73.9 0.0 9.7e-07 28.8 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 CDJ87804.1 - 2.1e-18 66.4 0.0 3.1e-10 40.2 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 CDJ87804.1 - 3.9e-16 59.0 0.0 5.4e-05 23.3 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 CDJ87804.1 - 6.4e-10 39.2 0.0 0.036 14.2 0.0 4.3 3 2 2 5 5 5 3 Immunoglobulin V-set domain Ig_5 PF16681.5 CDJ87804.1 - 4.6e-05 23.7 0.0 0.017 15.5 0.0 3.0 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 CDJ87804.1 - 8.3e-05 22.1 0.0 0.67 9.6 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain Izumo-Ig PF16706.5 CDJ87804.1 - 0.0019 18.2 0.0 0.3 11.2 0.0 2.9 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain GST_N_4 PF17172.4 CDJ87805.1 - 1.6e-29 102.6 0.0 2.8e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 CDJ87805.1 - 1.5e-24 85.5 0.1 2.6e-24 84.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 CDJ87805.1 - 2e-10 41.0 0.0 3.4e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 CDJ87805.1 - 3.1e-06 27.1 0.0 5.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDJ87805.1 - 5.1e-05 23.6 0.0 0.00014 22.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CDJ87805.1 - 0.001 19.4 0.0 0.0019 18.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Lactamase_B_6 PF16661.5 CDJ87806.1 - 2.4e-54 183.7 0.3 9.9e-54 181.7 0.1 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 CDJ87806.1 - 3.1e-24 86.1 3.7 1.9e-22 80.3 0.0 3.3 2 1 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 CDJ87806.1 - 1.9e-20 73.2 0.0 4.8e-20 71.9 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 CDJ87806.1 - 2.6e-15 56.1 0.0 5.6e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 CDJ87806.1 - 2.4e-09 37.5 0.0 3.8e-08 33.6 0.0 2.3 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CDJ87806.1 - 1.8e-06 27.6 0.0 4.7e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 CDJ87806.1 - 0.00015 21.1 0.0 0.00037 19.8 0.0 1.6 1 1 0 1 1 1 1 Putative beta-lactamase-like family NHL PF01436.21 CDJ87806.1 - 0.061 13.4 0.0 12 6.2 0.0 3.4 3 0 0 3 3 3 0 NHL repeat AA_kinase PF00696.28 CDJ87806.1 - 0.12 12.0 0.0 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 Amino acid kinase family Sorting_nexin PF03700.13 CDJ87806.1 - 0.13 12.9 2.4 0.31 11.6 2.4 1.6 1 0 0 1 1 1 0 Sorting nexin, N-terminal domain CheW PF01584.19 CDJ87806.1 - 0.18 11.5 0.0 0.64 9.7 0.0 1.9 2 0 0 2 2 2 0 CheW-like domain FemAB PF02388.16 CDJ87806.1 - 1.1 8.0 4.3 9.5 5.0 1.7 2.1 2 0 0 2 2 2 0 FemAB family Peptidase_M20 PF01546.28 CDJ87807.1 - 1.9e-33 116.0 0.0 2.4e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CDJ87807.1 - 1.9e-13 50.3 0.0 3.1e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CDJ87807.1 - 0.0012 18.6 0.0 0.0032 17.2 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 STI1 PF17830.1 CDJ87808.1 - 2.8e-13 49.6 3.5 4.5e-13 48.9 3.5 1.3 1 0 0 1 1 1 1 STI1 domain Methyltransf_2 PF00891.18 CDJ87808.1 - 0.25 10.6 0.1 0.25 10.6 0.1 1.6 2 0 0 2 2 2 0 O-methyltransferase domain DUF4278 PF14105.6 CDJ87809.1 - 0.2 12.1 16.1 44 4.6 0.1 8.6 8 2 0 8 8 8 0 Domain of unknown function (DUF4278) DUF5593 PF18007.1 CDJ87809.1 - 0.25 12.0 1.7 1.1 9.9 1.7 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5593) HipN PF18253.1 CDJ87810.1 - 3.9e-18 64.9 0.1 2.3e-17 62.4 0.1 2.0 2 0 0 2 2 2 1 Hsp70-interacting protein N N-terminal domain TPR_1 PF00515.28 CDJ87810.1 - 1.2e-16 59.7 4.4 4.1e-06 26.4 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ87810.1 - 9.6e-14 50.3 6.0 4.6e-05 23.2 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ87810.1 - 3.3e-09 36.3 2.8 0.0021 17.7 0.1 3.2 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.6 CDJ87810.1 - 1.1e-08 35.6 2.8 5.2e-07 30.2 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ87810.1 - 8.8e-07 28.9 0.3 0.00042 20.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ87810.1 - 1e-06 28.4 6.3 0.0042 17.2 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ87810.1 - 1.4e-06 28.5 2.6 0.0055 17.0 0.5 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ87810.1 - 1.4e-05 25.1 0.5 0.039 14.1 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ87810.1 - 1.8e-05 25.2 1.1 0.32 11.9 0.0 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ87810.1 - 0.00026 21.4 0.7 0.00069 20.1 0.2 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ87810.1 - 0.0099 15.8 0.1 0.5 10.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ87810.1 - 0.046 14.4 0.5 1.2 9.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ87810.1 - 0.069 13.0 0.4 17 5.4 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HemY_N PF07219.13 CDJ87810.1 - 0.17 12.1 0.3 0.38 11.0 0.3 1.5 1 0 0 1 1 1 0 HemY protein N-terminus Myosin_tail_1 PF01576.19 CDJ87813.1 - 5.3e-111 372.3 229.7 6.6e-111 371.9 229.7 1.0 1 0 0 1 1 1 1 Myosin tail Filament PF00038.21 CDJ87813.1 - 0.001 18.7 11.8 0.001 18.7 11.8 9.2 1 1 5 8 8 8 2 Intermediate filament protein HALZ PF02183.18 CDJ87813.1 - 0.0029 17.8 0.8 0.0029 17.8 0.8 9.1 10 1 1 11 11 11 3 Homeobox associated leucine zipper ATG16 PF08614.11 CDJ87813.1 - 0.0074 16.5 20.2 0.0074 16.5 20.2 9.8 1 1 8 9 9 9 3 Autophagy protein 16 (ATG16) Myosin_N PF02736.19 CDJ87814.1 - 6.4e-13 48.3 2.5 9e-13 47.8 2.5 1.2 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_head PF00063.21 CDJ87814.1 - 2.2e-06 26.2 0.1 3.1e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Peptidase_M8 PF01457.16 CDJ87815.1 - 1e-67 229.0 3.7 3.4e-67 227.3 3.7 1.7 1 1 0 1 1 1 1 Leishmanolysin BLM10_mid PF16507.5 CDJ87816.1 - 1.1e-14 54.0 1.8 2e-14 53.2 1.8 1.4 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region RP853 PF17542.2 CDJ87816.1 - 0.012 14.8 0.4 0.023 13.8 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized RP853 TIMELESS PF04821.14 CDJ87816.1 - 0.052 12.8 2.5 0.21 10.8 0.3 2.3 2 0 0 2 2 2 0 Timeless protein Prok-E2_B PF14461.6 CDJ87816.1 - 0.056 13.1 0.0 8.5 6.1 0.0 2.6 2 0 0 2 2 2 0 Prokaryotic E2 family B DNase_II PF03265.15 CDJ87818.1 - 2.4e-30 106.0 2.1 3.9e-23 82.2 0.2 2.0 1 1 1 2 2 2 2 Deoxyribonuclease II Astacin PF01400.24 CDJ87819.1 - 2.4e-47 161.0 0.6 2.8e-47 160.8 0.6 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 CDJ87819.1 - 0.09 12.6 0.2 0.37 10.6 0.2 1.8 1 1 1 2 2 2 0 Matrixin Metallopep PF12044.8 CDJ87819.1 - 0.1 11.2 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Putative peptidase family Astacin PF01400.24 CDJ87820.1 - 1.3e-48 165.2 1.5 1.8e-48 164.7 1.5 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) DUF21 PF01595.20 CDJ87821.1 - 5e-35 120.8 1.8 1.1e-34 119.7 1.8 1.5 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CDJ87821.1 - 2.1e-05 24.9 1.1 0.0051 17.2 0.0 2.9 2 0 0 2 2 2 2 CBS domain RT_RNaseH_2 PF17919.1 CDJ87822.1 - 5.4e-35 119.4 0.0 4.6e-34 116.4 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ87822.1 - 3.7e-31 107.5 0.0 1.4e-30 105.7 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ87822.1 - 3.3e-15 55.9 0.0 1.1e-14 54.3 0.0 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 CDJ87822.1 - 1.1e-14 54.5 0.0 2.2e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 CDJ87822.1 - 0.00016 21.8 0.1 0.00074 19.7 0.1 2.3 1 0 0 1 1 1 1 H2C2 zinc finger BAR PF03114.18 CDJ87823.1 - 2.2e-70 237.0 11.2 3.7e-70 236.3 11.2 1.4 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 CDJ87823.1 - 4.3e-16 58.9 5.8 1.9e-13 50.3 2.5 2.2 2 0 0 2 2 2 2 Bin/amphiphysin/Rvs domain for vesicular trafficking SH3_9 PF14604.6 CDJ87823.1 - 1.8e-12 46.9 0.0 2.8e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDJ87823.1 - 2.7e-12 46.1 0.0 4.8e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDJ87823.1 - 1.7e-11 43.6 0.0 3e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain STELLO PF03385.17 CDJ87823.1 - 0.06 12.2 1.3 0.091 11.6 1.3 1.2 1 0 0 1 1 1 0 STELLO glycosyltransferases FTZ PF03867.14 CDJ87823.1 - 1 8.9 5.5 1.5 8.3 2.1 2.2 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region Proteasome PF00227.26 CDJ87824.1 - 2.3e-30 105.5 0.0 2.8e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF424 PF04242.13 CDJ87824.1 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF424) RRF PF01765.19 CDJ87825.1 - 6.8e-25 87.9 0.3 6.8e-25 87.9 0.3 1.4 2 0 0 2 2 2 1 Ribosome recycling factor FtsJ PF01728.19 CDJ87827.1 - 1.7e-20 73.9 0.0 3.1e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase zf-CCHC_2 PF13696.6 CDJ87827.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Zinc knuckle TTR-52 PF01060.23 CDJ87828.1 - 2.9e-24 85.6 0.0 3.8e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Transthyretin-like family bMG3 PF11974.8 CDJ87828.1 - 0.029 14.4 0.0 0.039 14.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain TTR-52 PF01060.23 CDJ87829.1 - 1.5e-26 92.9 0.0 1.9e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Transthyretin-like family bMG3 PF11974.8 CDJ87829.1 - 0.013 15.6 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain DUF4198 PF10670.9 CDJ87829.1 - 0.047 14.1 0.0 0.068 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) Neur_chan_LBD PF02931.23 CDJ87830.1 - 1.3e-26 93.3 4.6 1.9e-26 92.9 4.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ87830.1 - 0.013 15.6 7.7 0.019 15.0 7.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3377 PF11857.8 CDJ87830.1 - 0.15 12.0 1.9 0.67 9.9 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) BatA PF07584.11 CDJ87830.1 - 0.15 12.4 0.1 0.15 12.4 0.1 1.8 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal ERCC4 PF02732.15 CDJ87831.1 - 0.027 14.7 0.2 0.097 12.9 0.0 1.8 2 0 0 2 2 2 0 ERCC4 domain Ribosomal_S6e PF01092.19 CDJ87832.1 - 0.034 14.1 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S6e MerT PF02411.15 CDJ87832.1 - 0.19 11.8 0.1 0.28 11.2 0.1 1.2 1 0 0 1 1 1 0 MerT mercuric transport protein Oxidored_q5_N PF01059.17 CDJ87833.1 - 0.16 12.1 13.8 0.032 14.3 6.4 2.7 1 1 2 3 3 3 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus Collagen PF01391.18 CDJ87834.1 - 1.5e-23 82.3 64.8 9.2e-11 41.3 27.6 3.1 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Glyco_transf_43 PF03360.16 CDJ87835.1 - 7.8e-48 163.0 0.0 9.3e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 43 SpoIIM PF01944.17 CDJ87835.1 - 0.15 12.1 1.8 0.5 10.4 1.8 2.0 1 1 0 1 1 1 0 Stage II sporulation protein M UNC-93 PF05978.16 CDJ87836.1 - 6.5e-57 191.6 12.2 6.5e-57 191.6 12.2 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 CDJ87836.1 - 5.3e-13 48.6 22.0 8.8e-13 47.9 21.0 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF5336 PF17270.2 CDJ87836.1 - 0.0013 18.4 0.1 0.0045 16.6 0.1 1.9 1 0 0 1 1 1 1 Family of unknown function (DUF5336) Acyl_transf_3 PF01757.22 CDJ87836.1 - 0.26 10.3 24.7 0.71 8.9 8.0 2.5 1 1 0 2 2 2 0 Acyltransferase family DUF2427 PF10348.9 CDJ87836.1 - 1.2 8.9 12.2 0.24 11.2 1.2 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) AAA_5 PF07728.14 CDJ87837.1 - 3.6e-100 331.5 0.0 6.3e-25 87.8 0.0 7.8 7 1 0 7 7 7 7 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 CDJ87837.1 - 1.4e-27 95.9 8.4 5.3e-11 42.7 0.4 5.0 4 0 0 4 4 4 3 Midasin AAA lid domain AAA PF00004.29 CDJ87837.1 - 1.3e-26 93.6 0.0 7.5e-05 23.2 0.0 7.6 7 1 0 7 7 7 5 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 CDJ87837.1 - 2e-24 85.9 0.0 8.5e-07 28.9 0.0 7.6 7 1 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ87837.1 - 8.7e-21 75.0 5.4 0.0003 21.2 0.4 7.4 6 2 0 6 6 6 5 AAA ATPase domain AAA_7 PF12775.7 CDJ87837.1 - 6.5e-18 64.9 1.0 4.4e-05 23.1 0.0 5.7 5 0 0 5 5 5 4 P-loop containing dynein motor region AAA_lid_5 PF17865.1 CDJ87837.1 - 4.1e-17 62.2 2.9 6.9e-16 58.2 1.4 3.1 2 1 0 2 2 2 1 Midasin AAA lid domain AAA_18 PF13238.6 CDJ87837.1 - 4.6e-15 56.3 0.7 0.029 14.9 0.0 7.0 6 0 0 6 6 6 2 AAA domain Sigma54_activat PF00158.26 CDJ87837.1 - 3.5e-14 52.9 0.2 0.014 15.1 0.0 5.9 6 0 0 6 6 5 3 Sigma-54 interaction domain TsaE PF02367.17 CDJ87837.1 - 4.6e-13 49.2 3.6 0.019 15.0 0.0 5.4 5 0 0 5 5 5 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynein_heavy PF03028.15 CDJ87837.1 - 7.6e-13 48.6 0.0 0.0018 18.3 0.0 4.7 4 0 0 4 4 4 2 Dynein heavy chain region D6 P-loop domain Mg_chelatase PF01078.21 CDJ87837.1 - 1.3e-12 47.5 1.2 0.001 18.5 0.0 7.7 7 1 0 7 7 7 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CDJ87837.1 - 6.1e-12 45.7 0.0 0.13 12.2 0.0 7.0 7 0 0 7 7 7 2 AAA domain AAA_22 PF13401.6 CDJ87837.1 - 3.7e-11 43.4 0.3 0.14 12.4 0.0 6.4 6 0 0 6 6 5 1 AAA domain AAA_6 PF12774.7 CDJ87837.1 - 4.6e-11 42.3 0.2 1.3 7.9 0.0 7.2 7 0 0 7 7 7 3 Hydrolytic ATP binding site of dynein motor region Sigma54_activ_2 PF14532.6 CDJ87837.1 - 4.7e-11 43.0 0.7 0.0008 19.5 0.0 6.1 6 0 0 6 6 6 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 CDJ87837.1 - 3.4e-10 39.9 0.9 0.0054 16.5 0.0 5.4 5 0 0 5 5 5 2 IstB-like ATP binding protein RNA_helicase PF00910.22 CDJ87837.1 - 2.6e-09 37.4 0.1 0.77 10.2 0.0 6.2 6 0 0 6 6 6 1 RNA helicase NACHT PF05729.12 CDJ87837.1 - 1.3e-08 35.0 6.6 0.39 10.6 0.0 5.9 5 0 0 5 5 5 2 NACHT domain T2SSE PF00437.20 CDJ87837.1 - 1.3e-08 34.2 2.1 0.24 10.4 0.0 4.9 5 0 0 5 5 5 2 Type II/IV secretion system protein PhoH PF02562.16 CDJ87837.1 - 2e-08 33.9 0.1 0.021 14.3 0.0 3.7 3 0 0 3 3 3 2 PhoH-like protein ABC_tran PF00005.27 CDJ87837.1 - 2.1e-08 34.8 2.2 0.32 11.5 0.0 5.7 6 0 0 6 6 5 2 ABC transporter AAA_25 PF13481.6 CDJ87837.1 - 4.1e-08 33.0 3.6 0.95 9.0 0.0 5.5 5 0 0 5 5 5 2 AAA domain AAA_8 PF12780.7 CDJ87837.1 - 6.6e-08 32.2 0.2 0.26 10.6 0.0 5.5 6 0 0 6 6 5 1 P-loop containing dynein motor region D4 AAA_30 PF13604.6 CDJ87837.1 - 1.2e-07 31.7 4.1 0.65 9.7 0.1 6.7 6 3 0 6 6 5 2 AAA domain AAA_33 PF13671.6 CDJ87837.1 - 1.9e-07 31.3 0.1 0.38 10.9 0.0 4.8 5 0 0 5 5 4 2 AAA domain AAA_29 PF13555.6 CDJ87837.1 - 2.8e-07 30.2 1.9 5.8 6.7 0.0 6.6 7 0 0 7 7 7 0 P-loop containing region of AAA domain DUF815 PF05673.13 CDJ87837.1 - 4.7e-07 29.2 1.0 0.15 11.2 0.0 4.1 4 0 0 4 4 4 2 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 CDJ87837.1 - 2e-06 27.2 1.5 5.8 6.1 0.0 5.1 5 0 0 5 5 5 0 Zeta toxin TIP49 PF06068.13 CDJ87837.1 - 4e-06 26.3 3.8 1.5 8.0 0.1 5.1 5 0 0 5 5 5 1 TIP49 P-loop domain Rad17 PF03215.15 CDJ87837.1 - 5.9e-06 26.3 3.3 0.46 10.4 0.1 5.2 5 0 0 5 5 4 1 Rad17 P-loop domain RuvB_N PF05496.12 CDJ87837.1 - 6.1e-06 26.1 4.4 3.3 7.5 0.1 5.2 5 1 0 5 5 4 0 Holliday junction DNA helicase RuvB P-loop domain AAA_23 PF13476.6 CDJ87837.1 - 9.2e-06 26.3 1.2 0.33 11.4 0.1 4.8 5 0 0 5 5 4 1 AAA domain RsgA_GTPase PF03193.16 CDJ87837.1 - 1.4e-05 25.1 7.9 0.1 12.5 0.1 5.7 7 0 0 7 7 6 2 RsgA GTPase DEAD PF00270.29 CDJ87837.1 - 1.8e-05 24.6 0.2 7.4 6.3 0.0 4.7 5 0 0 5 5 4 0 DEAD/DEAH box helicase TniB PF05621.11 CDJ87837.1 - 5.3e-05 22.7 0.4 1.6 8.1 0.0 4.2 4 0 0 4 4 3 1 Bacterial TniB protein ResIII PF04851.15 CDJ87837.1 - 5.7e-05 23.2 0.3 7.7 6.5 0.0 4.8 5 0 0 5 5 5 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 CDJ87837.1 - 0.00033 20.9 5.1 1.2 9.4 0.1 5.3 5 0 0 5 5 5 1 AAA domain PduV-EutP PF10662.9 CDJ87837.1 - 0.00051 19.8 4.6 0.51 10.1 0.0 4.6 5 0 0 5 5 5 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 CDJ87837.1 - 0.001 19.3 5.0 0.93 9.7 0.0 4.4 5 0 0 5 5 3 1 Ras of Complex, Roc, domain of DAPkinase IPT PF01745.16 CDJ87837.1 - 0.0017 17.8 1.9 23 4.3 0.0 5.6 6 0 0 6 6 6 0 Isopentenyl transferase NB-ARC PF00931.22 CDJ87837.1 - 0.002 17.4 2.2 3.9 6.6 0.0 3.7 4 0 0 4 4 3 0 NB-ARC domain ATPase PF06745.13 CDJ87837.1 - 0.0023 17.3 0.5 13 5.0 0.0 4.4 4 0 0 4 4 4 0 KaiC CPT PF07931.12 CDJ87837.1 - 0.0026 17.6 8.9 4.5 7.1 0.0 6.2 5 2 0 5 5 5 0 Chloramphenicol phosphotransferase-like protein Viral_helicase1 PF01443.18 CDJ87837.1 - 0.0027 17.5 0.0 0.52 10.0 0.0 4.3 6 0 0 6 6 5 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 CDJ87837.1 - 0.0038 17.1 0.1 2.8 7.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain dNK PF01712.19 CDJ87837.1 - 0.0058 16.5 0.6 11 5.8 0.0 4.7 4 0 0 4 4 4 0 Deoxynucleoside kinase MMR_HSR1 PF01926.23 CDJ87837.1 - 0.0087 16.1 2.1 7.9 6.6 0.2 4.1 4 0 0 4 4 3 0 50S ribosome-binding GTPase AAA_24 PF13479.6 CDJ87837.1 - 0.011 15.4 3.9 12 5.6 0.0 4.4 5 0 0 5 5 4 0 AAA domain AAA_2 PF07724.14 CDJ87837.1 - 0.018 15.2 0.0 42 4.2 0.0 4.5 5 0 0 5 5 4 0 AAA domain (Cdc48 subfamily) AAA_19 PF13245.6 CDJ87837.1 - 0.019 15.3 9.7 11 6.3 0.1 5.3 6 0 0 6 6 4 0 AAA domain CbiA PF01656.23 CDJ87837.1 - 0.021 14.9 0.2 44 4.1 0.2 4.2 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain Bac_DnaA PF00308.18 CDJ87837.1 - 0.024 14.5 0.0 4.1 7.2 0.0 2.7 2 0 0 2 2 2 0 Bacterial dnaA protein FtsK_SpoIIIE PF01580.18 CDJ87837.1 - 0.038 13.3 1.1 52 3.1 0.0 3.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_15 PF13175.6 CDJ87837.1 - 0.041 13.6 0.0 73 2.9 0.0 4.0 4 0 0 4 4 4 0 AAA ATPase domain AAA_17 PF13207.6 CDJ87837.1 - 0.042 14.3 1.5 4.3 7.8 0.1 4.1 4 0 0 4 4 3 0 AAA domain SMC_N PF02463.19 CDJ87837.1 - 0.094 12.1 0.0 36 3.7 0.0 4.3 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain ATP_bind_1 PF03029.17 CDJ87837.1 - 0.095 12.5 0.1 0.095 12.5 0.1 3.2 4 0 0 4 4 2 0 Conserved hypothetical ATP binding protein DUF2075 PF09848.9 CDJ87837.1 - 0.098 11.9 1.2 1.4 8.0 0.0 3.1 4 0 0 4 4 3 0 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 CDJ87837.1 - 0.1 12.5 0.0 45 3.9 0.0 4.3 5 0 0 5 5 5 0 ATPase domain predominantly from Archaea SRP54 PF00448.22 CDJ87837.1 - 1.7 8.3 5.1 3.2 7.3 0.0 3.6 4 0 0 4 4 3 0 SRP54-type protein, GTPase domain RVT_1 PF00078.27 CDJ87838.1 - 2.7e-09 36.9 0.0 3.1e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CagE_TrbE_VirB PF03135.14 CDJ87838.1 - 0.045 13.8 0.0 0.057 13.5 0.0 1.2 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system MAD PF05557.13 CDJ87838.1 - 0.09 11.1 0.1 0.1 10.9 0.1 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Phosphodiest PF01663.22 CDJ87839.1 - 8.6e-66 222.9 0.0 1.2e-65 222.5 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CDJ87839.1 - 0.063 12.7 0.0 1.2 8.5 0.0 2.4 1 1 0 1 1 1 0 Sulfatase CheX PF13690.6 CDJ87842.1 - 0.011 15.9 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 Chemotaxis phosphatase CheX Rubis-subs-bind PF09273.11 CDJ87842.1 - 0.58 10.9 10.4 0.99 10.1 10.4 1.4 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding NPAT_C PF15712.5 CDJ87842.1 - 3.7 6.1 11.6 4.1 5.9 11.6 1.1 1 0 0 1 1 1 0 NPAT C terminus Pex14_N PF04695.13 CDJ87842.1 - 4.7 7.8 17.6 0.83 10.3 13.6 1.8 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region V_ATPase_I PF01496.19 CDJ87842.1 - 7.1 4.4 12.5 8.3 4.2 12.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cytochrom_NNT PF03264.14 CDJ87842.1 - 9.3 5.9 8.8 15 5.2 8.8 1.2 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region FAM195 PF14799.6 CDJ87843.1 - 8.5e-05 22.8 0.6 0.0009 19.6 0.0 2.6 1 1 1 2 2 2 1 FAM195 family DUF3467 PF11950.8 CDJ87844.1 - 0.0015 18.7 0.0 0.0016 18.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3467) RIB43A PF05914.12 CDJ87844.1 - 0.015 14.0 7.4 0.015 14.0 7.4 1.0 1 0 0 1 1 1 0 RIB43A Ish1 PF10281.9 CDJ87844.1 - 0.076 13.3 0.1 0.15 12.4 0.1 1.5 1 1 0 1 1 1 0 Putative stress-responsive nuclear envelope protein zf-C4H2 PF10146.9 CDJ87844.1 - 0.13 12.6 4.7 0.14 12.5 4.7 1.0 1 0 0 1 1 1 0 Zinc finger-containing protein OmpH PF03938.14 CDJ87844.1 - 0.82 10.0 8.2 0.87 9.9 8.2 1.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA_9 PF12781.7 CDJ87844.1 - 0.84 8.7 6.1 0.95 8.5 6.1 1.1 1 0 0 1 1 1 0 ATP-binding dynein motor region Hormone_recep PF00104.30 CDJ87845.1 - 1.2e-43 149.1 4.5 2.2e-43 148.3 4.5 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 CDJ87845.1 - 1e-17 64.3 16.7 1.8e-17 63.5 16.7 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) 7tm_1 PF00001.21 CDJ87846.1 - 0.00021 20.7 16.0 0.00032 20.1 13.9 2.3 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) Antimicrobial10 PF08105.11 CDJ87847.1 - 0.082 13.0 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Metchnikowin family CAP PF00188.26 CDJ87848.1 - 1.6e-17 64.5 4.6 2.2e-17 64.1 4.6 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ87848.1 - 0.0016 18.7 4.6 0.028 14.7 4.6 2.4 1 1 0 1 1 1 1 Ancylostoma-associated secreted protein related CAP PF00188.26 CDJ87849.1 - 1.6e-17 64.5 4.6 2.2e-17 64.1 4.6 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ87849.1 - 0.0016 18.7 4.6 0.028 14.7 4.6 2.4 1 1 0 1 1 1 1 Ancylostoma-associated secreted protein related MFS_1 PF07690.16 CDJ87851.1 - 9.3e-48 162.9 30.4 1.5e-47 162.3 24.4 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ87851.1 - 3.1e-08 32.9 21.6 3.1e-08 32.9 21.6 3.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.13 CDJ87851.1 - 1.2e-05 24.0 2.5 1.2e-05 24.0 2.5 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector CAP PF00188.26 CDJ87853.1 - 3.9e-10 40.7 4.7 8.1e-10 39.6 4.7 1.5 1 1 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CDJ87854.1 - 4.4e-15 56.6 0.0 8.2e-15 55.8 0.0 1.5 1 1 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ87854.1 - 0.0029 17.9 5.0 0.033 14.5 3.6 2.5 2 1 0 2 2 2 1 Ancylostoma-associated secreted protein related Ion_trans PF00520.31 CDJ87856.1 - 1.7e-33 115.9 15.4 1.6e-32 112.7 15.6 2.0 1 1 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 CDJ87856.1 - 1.8e-16 60.3 0.2 8.3e-16 58.1 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 CDJ87856.1 - 2e-12 46.9 5.3 2e-12 46.9 5.3 2.3 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.12 CDJ87856.1 - 0.00075 18.3 3.1 0.00075 18.3 3.1 2.2 1 1 1 2 2 2 1 Polycystin cation channel DUF4190 PF13828.6 CDJ87856.1 - 0.013 15.3 2.3 0.63 9.8 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) BTB_3 PF16017.5 CDJ87856.1 - 0.018 15.1 0.0 0.052 13.6 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain Peptidase_A24 PF01478.18 CDJ87856.1 - 0.19 12.1 3.1 0.26 11.7 1.5 2.0 2 0 0 2 2 2 0 Type IV leader peptidase family DUF2542 PF10808.8 CDJ87856.1 - 2 9.0 5.5 0.48 10.9 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2542) GCP_N_terminal PF17681.1 CDJ87857.1 - 1.4e-16 61.0 0.3 2.3e-16 60.3 0.3 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CDJ87857.1 - 0.029 13.8 1.0 0.17 11.3 0.1 2.5 1 1 1 2 2 2 0 Gamma tubulin complex component C-terminal Bcl-2 PF00452.19 CDJ87857.1 - 0.29 11.9 1.3 15 6.3 0.3 2.8 2 0 0 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family CAP PF00188.26 CDJ87858.1 - 1.5e-15 58.2 0.2 1.8e-15 57.8 0.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ87858.1 - 0.052 13.8 0.2 0.17 12.2 0.2 1.8 1 1 0 1 1 1 0 Ancylostoma-associated secreted protein related CAP PF00188.26 CDJ87859.1 - 2.1e-17 64.1 0.5 3e-17 63.6 0.5 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ87859.1 - 0.0075 16.6 0.0 0.014 15.7 0.0 1.6 1 1 0 1 1 1 1 Ancylostoma-associated secreted protein related CAP PF00188.26 CDJ87860.1 - 9.6e-07 29.7 0.1 9.6e-07 29.7 0.1 2.0 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Forkhead_N PF08430.12 CDJ87860.1 - 0.0017 18.9 21.8 0.0032 18.1 21.8 1.4 1 0 0 1 1 1 1 Forkhead N-terminal region RAP1 PF07218.11 CDJ87860.1 - 0.0043 15.4 10.9 0.0048 15.3 10.9 1.0 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) ASPRs PF17641.2 CDJ87860.1 - 0.0056 17.0 1.0 0.0077 16.5 0.1 1.7 2 0 0 2 2 2 1 Ancylostoma-associated secreted protein related Mucin PF01456.17 CDJ87860.1 - 0.0059 16.6 15.8 0.0059 16.6 15.8 1.6 2 0 0 2 2 2 1 Mucin-like glycoprotein Apt1 PF10351.9 CDJ87860.1 - 0.12 11.2 9.3 0.14 11.0 9.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ87860.1 - 0.29 9.6 11.2 0.33 9.5 11.2 1.1 1 0 0 1 1 1 0 Macoilin family Miga PF10265.9 CDJ87860.1 - 2.9 6.7 8.6 3.5 6.5 8.6 1.2 1 0 0 1 1 1 0 Mitoguardin PI3K_1B_p101 PF10486.9 CDJ87860.1 - 6.7 4.4 12.5 9.8 3.8 12.5 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit FSA_C PF10479.9 CDJ87860.1 - 8.1 4.4 15.1 4.3 5.3 13.2 1.4 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus FAM199X PF15814.5 CDJ87860.1 - 8.2 5.4 17.8 12 4.9 17.8 1.2 1 0 0 1 1 1 0 Protein family FAM199X CAP PF00188.26 CDJ87861.1 - 7e-18 65.7 3.8 1e-17 65.1 3.8 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ87861.1 - 0.0024 18.1 1.6 0.015 15.6 1.7 2.3 1 1 0 1 1 1 1 Ancylostoma-associated secreted protein related CAP PF00188.26 CDJ87862.1 - 1.5e-16 61.4 1.4 2.1e-16 60.9 1.4 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ87862.1 - 0.0074 16.6 1.0 0.0076 16.5 0.1 1.5 2 0 0 2 2 2 1 Ancylostoma-associated secreted protein related Ion_trans PF00520.31 CDJ87863.1 - 2.1e-38 131.9 6.7 2.1e-38 131.9 6.7 1.5 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.22 CDJ87863.1 - 7.5e-19 67.9 0.0 2.9e-18 66.0 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 CDJ87863.1 - 1.9e-14 53.4 4.7 1.9e-14 53.4 4.7 1.9 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 CDJ87863.1 - 0.069 13.3 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 BTB/POZ domain TRAM_LAG1_CLN8 PF03798.16 CDJ87863.1 - 0.082 12.6 3.1 0.23 11.2 3.1 1.7 1 1 0 1 1 1 0 TLC domain DUF423 PF04241.15 CDJ87863.1 - 0.11 12.7 1.3 0.18 12.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF423) PKD_channel PF08016.12 CDJ87863.1 - 0.29 9.7 4.1 0.15 10.8 1.6 1.6 1 1 1 2 2 2 0 Polycystin cation channel Neur_chan_LBD PF02931.23 CDJ87864.1 - 6.4e-42 143.4 3.1 1e-41 142.8 3.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ87864.1 - 8.4e-24 84.9 4.9 1.5e-22 80.8 4.9 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Macro PF01661.21 CDJ87865.1 - 4.9e-39 133.0 3.0 6.3e-39 132.7 3.0 1.1 1 0 0 1 1 1 1 Macro domain DnaJ PF00226.31 CDJ87866.1 - 2.1e-18 66.2 0.3 2.1e-18 66.2 0.3 2.2 2 0 0 2 2 2 1 DnaJ domain RRM_1 PF00076.22 CDJ87866.1 - 4.7e-07 29.5 0.0 1.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Patched PF02460.18 CDJ87867.1 - 6.7e-123 411.5 18.0 3.1e-71 240.6 4.4 3.5 1 1 2 3 3 3 3 Patched family Sterol-sensing PF12349.8 CDJ87867.1 - 1.5e-25 89.8 20.8 4.1e-25 88.4 10.7 3.7 2 2 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 CDJ87867.1 - 0.0065 15.5 3.4 0.0065 15.5 3.4 2.2 2 0 0 2 2 2 1 MMPL family ACR_tran PF00873.19 CDJ87867.1 - 8 4.0 19.0 0.17 9.5 11.5 1.8 2 1 1 3 3 3 0 AcrB/AcrD/AcrF family TMEM51 PF15345.6 CDJ87868.1 - 0.011 15.6 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 TMEM154 PF15102.6 CDJ87868.1 - 0.013 15.4 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Stevor PF17410.2 CDJ87868.1 - 0.11 12.0 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame LRR_8 PF13855.6 CDJ87869.1 - 8.5e-23 79.9 11.5 2.4e-09 36.8 1.6 3.9 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CDJ87869.1 - 5.8e-22 77.4 9.4 3.3e-06 27.3 0.3 4.8 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CDJ87869.1 - 1e-10 40.8 16.1 0.01 15.9 0.1 7.8 7 0 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.33 CDJ87869.1 - 2.8e-07 30.1 7.8 7 7.6 0.0 7.1 7 0 0 7 7 7 2 Leucine Rich Repeat B3_4 PF03483.17 CDJ87869.1 - 5.8e-06 26.1 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain RNA_pol_Rpc82 PF05645.13 CDJ87869.1 - 0.012 15.3 0.3 0.032 14.0 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 Ribosomal_L17 PF01196.19 CDJ87870.1 - 3.2e-06 27.9 0.0 4.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 Pkinase_Tyr PF07714.17 CDJ87871.1 - 1.6e-48 165.2 0.0 2.4e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ87871.1 - 6e-41 140.6 0.0 8.6e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain C1_1 PF00130.22 CDJ87871.1 - 0.0004 20.2 10.5 0.00069 19.4 10.5 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SAM_KSR1 PF13543.6 CDJ87871.1 - 0.0078 16.4 0.1 0.018 15.2 0.0 1.6 2 0 0 2 2 2 1 SAM like domain present in kinase suppressor RAS 1 Kinase-like PF14531.6 CDJ87871.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 CDJ87871.1 - 0.15 11.4 0.1 0.28 10.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1518 PF07469.12 CDJ87871.1 - 0.51 10.8 14.4 0.051 14.0 8.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1518) Zona_pellucida PF00100.23 CDJ87872.1 - 1.1e-11 45.0 0.1 1.4e-11 44.7 0.1 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain ChitinaseA_N PF08329.10 CDJ87872.1 - 0.18 11.4 0.1 0.32 10.6 0.1 1.3 1 0 0 1 1 1 0 Chitinase A, N-terminal domain Ank_2 PF12796.7 CDJ87873.1 - 3.9e-40 136.3 2.3 1e-12 48.5 0.0 5.0 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ87873.1 - 5e-34 116.2 5.8 6.6e-08 33.0 0.2 8.1 5 3 3 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 CDJ87873.1 - 1e-30 104.8 17.6 7.5e-05 23.0 0.0 9.8 10 0 0 10 10 10 6 Ankyrin repeat Ank_3 PF13606.6 CDJ87873.1 - 7.8e-30 99.6 12.2 3.3e-05 23.9 0.0 9.5 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 CDJ87873.1 - 6.5e-27 93.3 4.4 1.6e-05 25.1 0.0 6.9 4 3 2 6 6 6 6 Ankyrin repeats (many copies) SOCS_box PF07525.16 CDJ87873.1 - 1.5e-11 44.4 3.2 7.2e-09 35.9 1.2 2.7 2 0 0 2 2 2 2 SOCS box Malectin PF11721.8 CDJ87874.1 - 3.8e-34 118.2 0.3 5e-34 117.8 0.3 1.1 1 0 0 1 1 1 1 Malectin domain Telomere_reg-2 PF10193.9 CDJ87877.1 - 3e-23 82.3 0.1 1.6e-22 80.0 0.1 2.4 1 0 0 1 1 1 1 Telomere length regulation protein BAH PF01426.18 CDJ87877.1 - 0.12 12.3 0.3 0.25 11.2 0.3 1.5 1 0 0 1 1 1 0 BAH domain Trypsin PF00089.26 CDJ87878.1 - 8.7e-61 205.5 0.5 1.1e-60 205.2 0.5 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CDJ87878.1 - 1e-08 35.5 0.1 2.3e-08 34.4 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 CDJ87878.1 - 0.00094 20.1 0.0 0.0015 19.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Neur_chan_LBD PF02931.23 CDJ87880.1 - 6.5e-46 156.5 1.3 9.3e-46 156.0 1.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ87880.1 - 6.2e-33 114.8 1.5 7.9e-33 114.5 1.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF4199 PF13858.6 CDJ87880.1 - 0.049 14.0 1.3 0.11 12.9 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Dis3l2_C_term PF17877.1 CDJ87880.1 - 0.054 13.8 0.0 0.21 11.9 0.0 2.0 2 0 0 2 2 2 0 DIS3-like exonuclease 2 C terminal DUF2976 PF11190.8 CDJ87880.1 - 0.09 12.6 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) GYF PF02213.16 CDJ87882.1 - 1e-09 37.9 0.1 1.5e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 GYF domain ATC_hydrolase PF14196.6 CDJ87883.1 - 0.016 15.9 0.1 0.02 15.7 0.1 1.1 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase HTH_48 PF17906.1 CDJ87883.1 - 0.017 15.3 0.6 0.035 14.2 0.6 1.6 1 1 0 1 1 1 0 HTH domain in Mos1 transposase DUF3602 PF12223.8 CDJ87883.1 - 0.032 14.8 0.2 0.058 14.0 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) HTH_32 PF13565.6 CDJ87883.1 - 0.062 13.9 0.5 0.12 13.1 0.1 1.7 2 0 0 2 2 2 0 Homeodomain-like domain FYVE PF01363.21 CDJ87884.1 - 1.3e-14 54.0 8.6 1.8e-14 53.6 8.6 1.2 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CDJ87884.1 - 0.0078 16.4 3.6 0.0099 16.1 3.6 1.2 1 0 0 1 1 1 1 FYVE-type zinc finger zf-B_box PF00643.24 CDJ87884.1 - 0.092 12.9 5.3 0.3 11.3 5.3 1.8 1 1 0 1 1 1 0 B-box zinc finger Ephrin_rec_like PF07699.13 CDJ87884.1 - 0.31 10.8 6.1 0.19 11.5 0.7 2.5 1 1 1 2 2 2 0 Putative ephrin-receptor like DUF1647 PF07801.11 CDJ87885.1 - 9.9e-36 122.6 0.0 1.8e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) DUF1647 PF07801.11 CDJ87886.1 - 4e-36 123.9 0.0 5.7e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) EVI2A PF05399.11 CDJ87886.1 - 2 7.9 3.3 3.2 7.3 3.3 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) DnaJ PF00226.31 CDJ87887.1 - 8.5e-05 22.6 0.0 0.00014 22.0 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 CDJ87887.1 - 0.0012 18.9 0.0 0.0016 18.5 0.0 1.1 1 0 0 1 1 1 1 Pam16 TPR_1 PF00515.28 CDJ87888.1 - 0.002 17.9 1.0 0.0067 16.2 0.5 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ87888.1 - 0.0042 17.3 1.4 0.01 16.1 0.4 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CDJ87888.1 - 0.12 12.5 0.3 0.41 10.9 0.3 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 CDJ87889.1 - 6.5e-08 32.4 0.1 1.2e-07 31.5 0.1 1.4 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain Pkinase_Tyr PF07714.17 CDJ87890.1 - 8.9e-55 185.8 0.0 1.1e-54 185.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ87890.1 - 9.7e-53 179.2 0.0 1.5e-52 178.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RBD PF02196.15 CDJ87890.1 - 2.4e-17 62.8 0.1 4.8e-17 61.8 0.1 1.6 1 0 0 1 1 1 1 Raf-like Ras-binding domain C1_1 PF00130.22 CDJ87890.1 - 2.3e-11 43.4 2.3 4.5e-11 42.5 2.3 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 CDJ87890.1 - 5e-06 26.7 1.9 1.1e-05 25.7 1.9 1.5 1 0 0 1 1 1 1 C1 domain Kinase-like PF14531.6 CDJ87890.1 - 5.4e-06 25.9 0.0 8.4e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CDJ87890.1 - 3.6e-05 22.7 0.0 5.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase zf-RING-like PF08746.11 CDJ87890.1 - 4.2 7.8 9.5 0.14 12.5 2.7 2.0 2 0 0 2 2 2 0 RING-like domain ATPase_gene1 PF09527.10 CDJ87891.1 - 0.086 13.0 2.4 0.68 10.1 0.4 2.1 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter PA PF02225.22 CDJ87892.1 - 0.00043 20.2 0.0 0.0006 19.8 0.0 1.2 1 0 0 1 1 1 1 PA domain Gaa1 PF04114.14 CDJ87893.1 - 6.9e-83 279.3 10.2 4.8e-82 276.6 10.2 1.9 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component Glycos_transf_2 PF00535.26 CDJ87894.1 - 9.8e-25 87.3 0.0 1.5e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 CDJ87894.1 - 2.3e-05 24.0 0.1 5e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 CDJ87894.1 - 0.00092 19.2 0.1 0.0073 16.2 0.1 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CDJ87894.1 - 0.0017 17.9 0.0 0.0051 16.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DUF1335 PF07056.11 CDJ87894.1 - 0.092 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1335) Pkinase_Tyr PF07714.17 CDJ87896.1 - 2.7e-86 289.0 0.0 4.4e-86 288.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ87896.1 - 5.6e-42 143.9 0.0 1.4e-41 142.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Ephrin_lbd PF01404.19 CDJ87896.1 - 1.9e-31 109.5 1.3 3e-31 108.8 1.3 1.3 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain EphA2_TM PF14575.6 CDJ87896.1 - 5.5e-18 65.6 0.0 1.5e-17 64.2 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain fn3 PF00041.21 CDJ87896.1 - 1.3e-13 51.1 3.5 9.7e-07 29.0 0.0 3.4 4 0 0 4 4 3 2 Fibronectin type III domain Ephrin_rec_like PF07699.13 CDJ87896.1 - 1.5e-07 31.0 8.4 2e-07 30.7 7.3 1.8 1 1 1 2 2 2 1 Putative ephrin-receptor like SAM_2 PF07647.17 CDJ87896.1 - 1.5e-05 25.0 0.0 3.4e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) fn3_2 PF16893.5 CDJ87896.1 - 0.00028 21.0 0.1 0.0041 17.2 0.0 2.7 2 1 0 2 2 1 1 Fibronectin type III domain DUF4381 PF14316.6 CDJ87896.1 - 0.0019 18.5 0.1 0.0047 17.2 0.0 1.6 2 0 0 2 2 1 1 Domain of unknown function (DUF4381) RCR PF12273.8 CDJ87896.1 - 0.011 16.3 0.0 0.024 15.3 0.0 1.5 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Pur_ac_phosph_N PF16656.5 CDJ87896.1 - 0.021 15.4 0.3 0.75 10.4 0.0 3.2 3 1 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain Haspin_kinase PF12330.8 CDJ87896.1 - 0.054 12.4 0.0 0.083 11.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain cEGF PF12662.7 CDJ87896.1 - 1.6 8.8 11.2 11 6.1 0.6 2.8 2 0 0 2 2 2 0 Complement Clr-like EGF-like RNA_pol PF00940.19 CDJ87897.1 - 2.8e-132 441.5 0.0 4.9e-132 440.7 0.0 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 CDJ87897.1 - 1.5e-10 41.0 0.0 3.3e-10 39.9 0.0 1.6 1 1 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Cnd1_N PF12922.7 CDJ87897.1 - 0.086 12.7 1.0 3.6 7.4 0.0 2.8 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1, N-term TetR_C_6 PF13977.6 CDJ87897.1 - 0.16 12.2 0.0 8.3 6.7 0.0 2.7 3 0 0 3 3 3 0 BetI-type transcriptional repressor, C-terminal YvrJ PF12841.7 CDJ87897.1 - 0.17 11.4 0.3 0.35 10.4 0.3 1.5 1 0 0 1 1 1 0 YvrJ protein family Srg PF02118.21 CDJ87898.1 - 5e-26 92.0 44.5 7.5e-15 55.3 22.4 2.1 2 0 0 2 2 2 2 Srg family chemoreceptor 7TM_GPCR_Srv PF10323.9 CDJ87898.1 - 1.9e-14 53.7 41.6 1.7e-07 30.9 19.9 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv DUF4059 PF13268.6 CDJ87898.1 - 0.0031 17.9 5.5 0.35 11.3 1.0 3.4 2 1 0 2 2 2 2 Protein of unknown function (DUF4059) PufQ PF05398.11 CDJ87898.1 - 0.017 15.2 2.8 1.9 8.6 0.0 3.2 3 0 0 3 3 3 0 PufQ cytochrome subunit Sugar_transport PF06800.12 CDJ87898.1 - 0.94 8.7 8.7 0.21 10.9 0.3 2.4 3 0 0 3 3 3 0 Sugar transport protein DUF1772 PF08592.11 CDJ87898.1 - 1.4 9.2 6.4 15 5.9 0.7 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF1772) TMEM132D_C PF15706.5 CDJ87898.1 - 4 7.3 5.7 24 4.8 0.1 2.8 2 1 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term F-box PF00646.33 CDJ87899.1 - 0.00012 21.8 0.2 0.00034 20.4 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDJ87899.1 - 0.00025 20.8 0.6 0.00047 20.0 0.6 1.5 1 0 0 1 1 1 1 F-box-like DUF2293 PF10056.9 CDJ87900.1 - 0.096 12.9 0.1 0.096 12.9 0.1 2.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2293) MFS_1 PF07690.16 CDJ87902.1 - 1.3e-20 73.6 26.6 2.1e-20 73.0 26.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2070 PF09843.9 CDJ87902.1 - 9.2 4.4 30.1 0.27 9.5 9.9 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) BTB PF00651.31 CDJ87903.1 - 4.7e-26 91.2 1.0 3.7e-25 88.3 0.4 2.6 1 1 1 2 2 2 1 BTB/POZ domain zf-C2H2 PF00096.26 CDJ87903.1 - 1.4e-15 56.8 62.7 0.0013 19.1 2.0 9.2 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ87903.1 - 2.9e-15 55.9 50.0 8e-06 26.1 0.5 10.4 10 0 0 10 10 10 5 Zinc-finger double domain zf-H2C2_5 PF13909.6 CDJ87903.1 - 9.2e-08 31.7 62.0 1.9e-06 27.5 1.5 8.3 8 0 0 8 8 8 3 C2H2-type zinc-finger domain BACK PF07707.15 CDJ87903.1 - 2.3e-07 30.9 0.1 9e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch zf-C2H2_4 PF13894.6 CDJ87903.1 - 4.5e-06 27.0 70.5 0.038 14.8 1.3 10.1 10 0 0 10 10 9 5 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CDJ87903.1 - 0.001 19.3 24.8 0.0042 17.3 3.2 4.8 1 1 4 5 5 5 2 C2H2-type zinc ribbon zf_C2H2_ZHX PF18387.1 CDJ87903.1 - 0.0022 17.6 37.2 0.21 11.2 0.1 7.5 5 3 3 8 8 8 3 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 CDJ87903.1 - 0.007 16.6 0.5 0.007 16.6 0.5 6.9 8 0 0 8 8 8 2 Zinc-finger double-stranded RNA-binding SAP130_C PF16014.5 CDJ87903.1 - 0.028 13.5 1.5 0.045 12.8 1.5 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus DUF3342 PF11822.8 CDJ87903.1 - 0.033 14.4 0.4 0.087 13.0 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) Exo70 PF03081.15 CDJ87903.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Exo70 exocyst complex subunit SpdB PF05122.13 CDJ87903.1 - 1.7 8.9 5.0 1.4 9.1 1.7 2.7 1 1 1 2 2 2 0 Mobile element transfer protein zinc_ribbon_15 PF17032.5 CDJ87903.1 - 2.5 8.9 27.4 0.8 10.5 2.2 5.1 3 1 2 5 5 5 0 zinc-ribbon family zf-C2HC_2 PF13913.6 CDJ87903.1 - 2.9 7.9 11.6 0.46 10.5 1.2 3.0 3 0 0 3 3 2 0 zinc-finger of a C2HC-type ADK_lid PF05191.14 CDJ87903.1 - 8.8 6.4 13.1 0.73 9.9 0.6 3.3 3 0 0 3 3 3 0 Adenylate kinase, active site lid Peptidase_S9 PF00326.21 CDJ87904.1 - 2.8e-31 108.7 0.0 5.3e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CDJ87904.1 - 6e-08 32.7 0.4 8.1e-05 22.4 1.2 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold PD40 PF07676.12 CDJ87904.1 - 0.0002 21.2 0.2 0.0038 17.1 0.0 2.6 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Hydrolase_4 PF12146.8 CDJ87904.1 - 0.00042 19.7 0.0 0.012 14.9 0.0 2.2 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 CDJ87904.1 - 0.00086 19.0 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase BAAT_C PF08840.11 CDJ87904.1 - 0.0016 18.4 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 CDJ87904.1 - 0.0043 17.7 5.4 0.099 13.2 5.4 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 CDJ87904.1 - 0.037 13.6 0.0 0.12 12.0 0.0 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family DUF4598 PF15370.6 CDJ87904.1 - 8.3 6.9 8.9 1.6e+02 2.8 8.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4598) PUB PF09409.10 CDJ87905.1 - 2.1e-22 78.8 0.0 4.5e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 PUB domain UBX PF00789.20 CDJ87905.1 - 2.4e-06 27.6 0.0 5.5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 UBX domain MAS20 PF02064.15 CDJ87905.1 - 0.061 13.4 0.2 0.061 13.4 0.2 2.0 2 0 0 2 2 2 0 MAS20 protein import receptor Steroid_dh PF02544.16 CDJ87906.1 - 9.4e-57 191.2 0.3 9.4e-57 191.2 0.3 1.8 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 CDJ87906.1 - 5.4e-05 22.8 1.6 0.00015 21.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Sdh_cyt PF01127.22 CDJ87906.1 - 1.1 9.3 11.1 1.6 8.8 8.7 2.4 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4131 PF13567.6 CDJ87906.1 - 1.2 8.8 5.0 0.76 9.4 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) zf-CCCH_2 PF14608.6 CDJ87907.1 - 2.8e-05 24.4 5.8 2.8e-05 24.4 5.8 3.8 3 0 0 3 3 3 1 RNA-binding, Nab2-type zinc finger zf-C2H2_4 PF13894.6 CDJ87907.1 - 0.003 18.3 10.5 0.96 10.5 0.3 4.9 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CDJ87907.1 - 0.021 15.1 3.6 0.021 15.1 3.6 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Apt1 PF10351.9 CDJ87907.1 - 0.024 13.5 15.5 0.028 13.3 15.5 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ndc1_Nup PF09531.10 CDJ87907.1 - 0.026 13.2 6.0 0.029 13.1 6.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PI3K_1B_p101 PF10486.9 CDJ87907.1 - 0.19 9.4 12.4 0.26 9.0 12.4 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TFIIF_alpha PF05793.12 CDJ87907.1 - 0.2 10.2 36.5 0.32 9.5 36.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF936 PF06075.12 CDJ87907.1 - 0.22 10.4 22.7 0.32 9.8 22.7 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) zf_C2H2_ZHX PF18387.1 CDJ87907.1 - 0.52 10.0 6.1 8.6 6.1 1.7 2.7 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Macoilin PF09726.9 CDJ87907.1 - 0.6 8.6 17.5 0.8 8.2 17.5 1.1 1 0 0 1 1 1 0 Macoilin family zf-C2H2 PF00096.26 CDJ87907.1 - 1.1 9.8 16.7 0.27 11.8 0.4 4.4 4 0 0 4 4 3 0 Zinc finger, C2H2 type Exo_endo_phos_2 PF14529.6 CDJ87909.1 - 0.0046 16.8 0.0 0.0074 16.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF229 PF02995.17 CDJ87910.1 - 2.7e-60 204.4 0.4 3e-60 204.3 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 CDJ87910.1 - 0.032 13.6 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Sulfatase Leader_CPA1 PF08252.11 CDJ87910.1 - 0.84 9.1 4.5 10 5.6 0.0 3.0 3 0 0 3 3 3 0 arg-2/CPA1 leader peptide WAP PF00095.21 CDJ87911.1 - 8e-08 32.6 12.2 1.3e-07 31.9 12.2 1.3 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Conotoxin_I2 PF17557.2 CDJ87911.1 - 0.14 12.2 11.8 0.34 11.0 11.8 1.7 1 0 0 1 1 1 0 I2-superfamily conotoxins Thyroglobulin_1 PF00086.18 CDJ87912.1 - 4.7e-24 83.8 3.8 3e-11 42.8 0.0 3.2 2 0 0 2 2 2 2 Thyroglobulin type-1 repeat Lustrin_cystein PF14625.6 CDJ87912.1 - 6e-17 61.7 39.3 7.9e-09 35.7 6.4 12.4 10 3 3 13 13 13 5 Lustrin, cysteine-rich repeated domain WAP PF00095.21 CDJ87912.1 - 2.4e-10 40.7 30.8 8.5e-08 32.5 11.6 10.0 7 3 1 8 8 8 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' Antistasin PF02822.14 CDJ87912.1 - 2.3e-06 28.1 9.8 2.3e-06 28.1 9.8 10.3 12 1 0 12 12 12 2 Antistasin family PhyH PF05721.13 CDJ87913.1 - 6.4e-59 199.7 0.0 7.4e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RNase_E_G PF10150.9 CDJ87913.1 - 0.021 14.3 0.1 0.039 13.4 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease E/G family DUF2151 PF10221.9 CDJ87914.1 - 0.00038 19.2 0.0 0.00038 19.2 0.0 1.0 1 0 0 1 1 1 1 Cell cycle and development regulator DUF2151 PF10221.9 CDJ87915.1 - 1.5e-111 374.2 0.1 8.4e-73 246.1 0.0 2.0 1 1 1 2 2 2 2 Cell cycle and development regulator PPTA PF01239.22 CDJ87916.1 - 4.3e-44 147.0 11.5 6.3e-09 35.3 0.1 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_14 PF13428.6 CDJ87916.1 - 0.0013 19.3 0.0 34 5.6 0.0 4.7 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ87916.1 - 0.0015 18.8 1.0 1.6 9.3 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat DEK_C PF08766.11 CDJ87916.1 - 0.021 14.7 0.0 0.059 13.3 0.0 1.8 1 0 0 1 1 1 0 DEK C terminal domain F-box-like_2 PF13013.6 CDJ87916.1 - 0.065 13.2 0.8 4.8 7.2 0.1 2.9 3 0 0 3 3 3 0 F-box-like domain Dor1 PF04124.12 CDJ87917.1 - 1.7e-78 263.7 0.5 2.7e-78 263.0 0.5 1.3 1 0 0 1 1 1 1 Dor1-like family WD40 PF00400.32 CDJ87920.1 - 2.7e-13 50.2 15.6 0.0001 23.0 0.2 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ87920.1 - 0.00036 20.8 0.6 17 5.8 0.0 5.2 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.10 CDJ87920.1 - 0.035 13.2 0.0 0.088 11.8 0.0 1.6 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain TFIIIC_delta PF12657.7 CDJ87920.1 - 0.051 13.5 1.1 0.16 11.9 0.2 2.4 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Coatomer_WDAD PF04053.14 CDJ87920.1 - 0.057 12.5 2.7 0.2 10.7 1.2 2.3 3 0 0 3 3 3 0 Coatomer WD associated region Iso_dh PF00180.20 CDJ87921.1 - 2e-53 181.8 0.0 2.2e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HAD_2 PF13419.6 CDJ87923.1 - 0.00061 19.9 0.0 0.0045 17.1 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase UPF0449 PF15136.6 CDJ87924.1 - 0.021 15.3 0.1 0.61 10.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 GPS2_interact PF15784.5 CDJ87924.1 - 0.035 14.5 0.0 0.085 13.3 0.0 1.6 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain GyrB_insert PF18053.1 CDJ87924.1 - 0.12 12.3 0.1 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 DNA gyrase B subunit insert domain DASH_Dad3 PF08656.10 CDJ87924.1 - 0.14 12.3 1.9 0.64 10.2 0.3 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF4298 PF14131.6 CDJ87924.1 - 0.18 11.8 1.7 3.2 7.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) DUF3939 PF13075.6 CDJ87925.1 - 0.024 14.7 1.2 0.025 14.6 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3939) PP-binding PF00550.25 CDJ87925.1 - 0.039 14.3 0.2 0.12 12.8 0.0 1.9 2 1 1 3 3 3 0 Phosphopantetheine attachment site Col_cuticle_N PF01484.17 CDJ87927.1 - 2.1e-19 69.3 0.3 2.6e-19 69.0 0.3 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ87927.1 - 3.3e-19 68.4 135.4 1.1e-09 37.8 40.8 4.6 2 2 1 3 3 3 3 Collagen triple helix repeat (20 copies) COX14 PF14880.6 CDJ87927.1 - 0.023 14.5 2.3 0.033 14.0 2.3 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Collagen PF01391.18 CDJ87928.1 - 1.3e-18 66.5 140.2 1.6e-08 34.1 48.4 4.5 2 2 0 3 3 3 3 Collagen triple helix repeat (20 copies) Collagen PF01391.18 CDJ87929.1 - 6.1e-19 67.5 141.4 2e-09 37.1 41.6 5.0 2 2 0 3 3 3 2 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ87929.1 - 0.0015 18.6 0.1 0.0019 18.2 0.1 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Col_cuticle_N PF01484.17 CDJ87930.1 - 5e-20 71.3 0.1 6.3e-20 71.0 0.1 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ87930.1 - 1.9e-17 62.8 139.2 1.8e-08 34.0 47.4 4.3 2 2 1 3 3 3 3 Collagen triple helix repeat (20 copies) COX14 PF14880.6 CDJ87930.1 - 0.014 15.2 2.3 0.022 14.6 2.3 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Collagen PF01391.18 CDJ87931.1 - 2.8e-21 75.0 120.8 1e-08 34.8 47.2 4.0 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ87931.1 - 2.5e-20 72.3 0.2 3.2e-20 71.9 0.2 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain COX14 PF14880.6 CDJ87931.1 - 0.078 12.8 2.0 0.11 12.3 2.0 1.1 1 0 0 1 1 1 0 Cytochrome oxidase c assembly RRM_1 PF00076.22 CDJ87934.1 - 7.6e-20 70.5 0.0 1.8e-16 59.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 CDJ87934.1 - 2.1e-18 67.1 3.8 2.4e-18 67.0 0.7 2.6 2 1 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein PRP38_assoc PF12871.7 CDJ87934.1 - 0.00043 20.8 41.8 0.00043 20.8 41.8 1.6 2 0 0 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Apt1 PF10351.9 CDJ87934.1 - 0.0061 15.5 6.3 0.0072 15.2 6.3 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain RRM_occluded PF16842.5 CDJ87934.1 - 0.031 14.1 0.0 0.97 9.3 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_3 PF08777.11 CDJ87934.1 - 0.032 14.3 0.0 0.089 12.9 0.0 1.8 1 0 0 1 1 1 0 RNA binding motif RRM_5 PF13893.6 CDJ87934.1 - 0.042 13.4 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSRP PF17069.5 CDJ87934.1 - 0.25 10.9 31.9 0.39 10.2 31.9 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 CytochromB561_N PF09786.9 CDJ87934.1 - 0.86 8.5 4.5 1.2 8.1 4.5 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal CDC45 PF02724.14 CDJ87934.1 - 1.1 7.5 19.4 1.6 6.9 19.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CDJ87934.1 - 2.2 7.0 11.3 3.1 6.5 11.3 1.1 1 0 0 1 1 1 0 Presenilin Striatin PF08232.12 CDJ87934.1 - 6.1 7.4 16.1 11 6.6 16.1 1.3 1 0 0 1 1 1 0 Striatin family SLC12 PF03522.15 CDJ87934.1 - 8.1 5.4 8.2 12 4.8 8.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Peptidase_M1 PF01433.20 CDJ87935.1 - 5.9e-63 212.3 0.1 1.2e-62 211.4 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 CDJ87935.1 - 1.2e-38 133.5 0.0 1.7e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Helitron_like_N PF14214.6 CDJ87935.1 - 0.16 12.2 0.0 16 5.7 0.0 2.3 2 0 0 2 2 2 0 Helitron helicase-like domain at N-terminus P2_Phage_GpR PF06891.11 CDJ87936.1 - 0.016 15.3 0.5 0.037 14.1 0.5 1.7 1 0 0 1 1 1 0 P2 phage tail completion protein R (GpR) Cas_Cas4 PF01930.17 CDJ87936.1 - 2.7 8.1 10.7 0.21 11.7 0.4 2.5 1 1 1 2 2 2 0 Domain of unknown function DUF83 fn3 PF00041.21 CDJ87939.1 - 2.2e-266 861.2 129.7 2.6e-14 53.3 0.2 36.0 34 1 1 35 35 35 32 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CDJ87939.1 - 1.1e-44 150.9 69.7 0.0025 18.3 0.1 28.9 28 5 1 29 29 29 12 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 CDJ87939.1 - 3.7e-13 49.7 0.6 0.22 11.9 0.0 14.6 20 0 0 20 20 18 1 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 CDJ87939.1 - 5.1e-12 46.0 0.8 7.8 7.0 0.0 13.5 16 0 0 16 16 15 1 Uncharacterised conserved protein (DUF2369) fn3_4 PF16794.5 CDJ87939.1 - 2.4e-06 27.4 0.1 49 3.9 0.0 9.3 11 0 0 11 11 11 0 Fibronectin-III type domain Glyco_hydro_36C PF16874.5 CDJ87939.1 - 3.2e-06 27.5 0.1 81 3.8 0.0 10.4 13 0 0 13 13 11 0 Glycosyl hydrolase family 36 C-terminal domain PhoD_N PF16655.5 CDJ87939.1 - 3.7e-05 24.2 5.7 25 5.5 0.0 9.2 10 1 0 10 10 10 0 PhoD-like phosphatase, N-terminal domain Tissue_fac PF01108.17 CDJ87939.1 - 0.00013 21.7 33.6 0.9 9.4 0.1 11.9 13 1 1 14 14 13 3 Tissue factor fn3_2 PF16893.5 CDJ87939.1 - 0.012 15.7 0.0 1.3e+02 2.8 0.0 7.0 9 0 0 9 9 9 0 Fibronectin type III domain NAR2 PF16974.5 CDJ87939.1 - 0.014 14.8 0.1 0.92 8.9 0.0 4.0 4 0 0 4 4 4 0 High-affinity nitrate transporter accessory TMEM52 PF14979.6 CDJ87939.1 - 0.087 12.7 0.7 0.25 11.3 0.7 1.7 1 0 0 1 1 1 0 Transmembrane 52 DUF4381 PF14316.6 CDJ87939.1 - 0.12 12.7 1.8 0.25 11.6 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CAP PF00188.26 CDJ87940.1 - 1.2e-10 42.3 0.5 1.2e-10 42.3 0.5 2.4 2 1 1 3 3 3 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ87940.1 - 0.028 14.7 0.8 0.086 13.1 0.1 2.2 1 1 1 2 2 2 0 Ancylostoma-associated secreted protein related RVT_1 PF00078.27 CDJ87941.1 - 4.2e-14 52.6 0.0 5.9e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MerT PF02411.15 CDJ87941.1 - 0.094 12.8 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 MerT mercuric transport protein ShK PF01549.24 CDJ87942.1 - 0.0012 19.3 5.5 0.0012 19.3 5.5 2.4 2 0 0 2 2 2 2 ShK domain-like Cadherin_C_2 PF16492.5 CDJ87942.1 - 0.032 15.0 0.9 0.054 14.2 0.9 1.4 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal Spermine_synth PF01564.17 CDJ87943.1 - 2.2e-07 30.5 0.0 3.7e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_31 PF13847.6 CDJ87943.1 - 0.0034 17.2 0.1 0.008 16.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ87943.1 - 0.023 15.3 0.0 0.11 13.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.19 CDJ87943.1 - 0.032 14.0 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 CDJ87943.1 - 0.04 14.6 0.0 0.092 13.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CDJ87943.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain CHGN PF05679.16 CDJ87944.1 - 1.4e-113 380.5 0.0 1.6e-113 380.3 0.0 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 CDJ87944.1 - 0.00046 19.7 0.0 0.00091 18.7 0.0 1.6 1 0 0 1 1 1 1 Fringe-like Cullin PF00888.22 CDJ87945.1 - 2.2e-149 498.9 0.2 2.7e-149 498.7 0.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CDJ87945.1 - 2.1e-26 91.8 2.6 5.2e-26 90.5 2.6 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain HSP20 PF00011.21 CDJ87946.1 - 3e-22 78.7 0.1 3.9e-22 78.3 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ87946.1 - 0.00075 19.0 0.1 0.0015 18.1 0.0 1.6 2 0 0 2 2 2 1 HSP20-like domain found in ArsA HSP20 PF00011.21 CDJ87947.1 - 8.6e-21 74.0 0.0 1.1e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ87947.1 - 2.5e-05 23.7 0.0 4.7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF5640 PF18692.1 CDJ87947.1 - 0.032 14.3 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5640) YopE_N PF09020.10 CDJ87947.1 - 0.12 12.6 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 YopE, N terminal HSP20 PF00011.21 CDJ87948.1 - 6.5e-17 61.5 0.0 8.8e-17 61.1 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ87948.1 - 0.0066 16.0 0.0 0.013 15.1 0.0 1.5 1 1 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 CDJ87949.1 - 1.9e-21 76.1 0.0 2.4e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ87949.1 - 0.00039 19.9 0.0 0.00055 19.5 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF5640 PF18692.1 CDJ87949.1 - 0.077 13.0 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5640) HSP20 PF00011.21 CDJ87950.1 - 6.4e-21 74.4 0.1 9.6e-21 73.9 0.1 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ87950.1 - 0.0027 17.2 0.0 0.0056 16.2 0.0 1.6 1 0 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 CDJ87951.1 - 2.6e-21 75.7 0.1 3.5e-21 75.3 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ87951.1 - 0.0085 15.6 0.0 0.019 14.5 0.0 1.6 2 0 0 2 2 2 1 HSP20-like domain found in ArsA HSP20 PF00011.21 CDJ87952.1 - 1.7e-23 82.7 0.4 2.1e-23 82.4 0.4 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ87952.1 - 0.00054 19.5 0.0 0.00083 18.9 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 CDJ87953.1 - 2.6e-21 75.7 0.1 3.3e-21 75.4 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ87953.1 - 0.00016 21.1 0.0 0.00026 20.5 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF5640 PF18692.1 CDJ87953.1 - 0.082 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5640) HSP20 PF00011.21 CDJ87954.1 - 9.1e-23 80.4 0.3 1.1e-22 80.1 0.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ87954.1 - 0.00049 19.6 0.0 0.00075 19.0 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF4164 PF13747.6 CDJ87954.1 - 0.044 14.1 0.0 0.088 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) HSP20 PF00011.21 CDJ87955.1 - 7.7e-20 71.0 0.0 1e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ87955.1 - 0.00088 18.8 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF5640 PF18692.1 CDJ87955.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5640) HSP20 PF00011.21 CDJ87956.1 - 1.5e-18 66.8 0.0 2.7e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ87956.1 - 0.0014 18.1 0.0 0.0026 17.3 0.0 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Adhes-Ig_like PF09085.10 CDJ87956.1 - 0.093 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Adhesion molecule, immunoglobulin-like PSI_PsaH PF03244.14 CDJ87956.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VI HflK_N PF12221.8 CDJ87958.1 - 1.6 8.8 5.7 0.43 10.6 0.8 2.6 2 0 0 2 2 2 0 Bacterial membrane protein N terminal Rhomboid PF01694.22 CDJ87959.1 - 6.4e-37 126.9 12.0 6.4e-37 126.9 12.0 2.3 2 1 1 3 3 3 1 Rhomboid family EF-hand_7 PF13499.6 CDJ87959.1 - 2.9e-12 46.9 0.1 5e-12 46.1 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CDJ87959.1 - 2.2e-11 42.4 0.1 0.0001 21.6 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CDJ87959.1 - 1.5e-09 37.0 0.2 3.7e-05 23.3 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CDJ87959.1 - 2.3e-09 37.0 1.1 7.6e-06 25.7 0.1 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ87959.1 - 0.0005 19.5 0.3 0.026 14.0 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 CDJ87959.1 - 0.0017 18.7 0.0 0.0034 17.7 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain DUF3087 PF11286.8 CDJ87959.1 - 0.37 10.2 1.7 0.42 10.1 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Glycos_transf_2 PF00535.26 CDJ87960.1 - 5.6e-31 107.6 0.0 1.1e-30 106.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CDJ87960.1 - 2.6e-18 66.5 0.1 4.4e-18 65.8 0.1 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 CDJ87960.1 - 1.3e-06 28.0 0.1 3e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase TUDOR PF00567.24 CDJ87961.1 - 2.7e-24 85.5 0.0 3.7e-13 49.6 0.0 2.3 2 0 0 2 2 2 2 Tudor domain VHP PF02209.19 CDJ87962.1 - 9.5e-17 60.8 0.5 2.5e-16 59.4 0.5 1.8 1 0 0 1 1 1 1 Villin headpiece domain Gelsolin PF00626.22 CDJ87962.1 - 1.6e-08 34.3 0.1 0.037 13.9 0.0 4.4 4 0 0 4 4 4 3 Gelsolin repeat p47_phox_C PF08944.11 CDJ87962.1 - 1.8 8.0 7.1 2.2 7.8 0.0 2.9 2 1 1 3 3 3 0 NADPH oxidase subunit p47Phox, C terminal domain Sec8_exocyst PF04048.14 CDJ87963.1 - 3.8e-11 43.0 1.8 1.2e-10 41.5 0.8 2.3 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain EzrA PF06160.12 CDJ87963.1 - 0.0017 16.6 0.8 0.0043 15.3 0.8 1.6 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA Vps54_N PF10475.9 CDJ87963.1 - 0.0037 16.6 4.2 0.0086 15.4 4.2 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF1216 PF06746.11 CDJ87963.1 - 0.047 13.7 0.2 0.37 10.8 0.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1216) DUF2009 PF09418.10 CDJ87963.1 - 0.056 12.5 0.2 0.19 10.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2009) 4HB_MCP_1 PF12729.7 CDJ87963.1 - 0.066 12.7 0.3 0.81 9.2 0.0 2.7 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction HTH_30 PF13556.6 CDJ87963.1 - 0.11 12.3 1.2 5 7.0 0.1 3.2 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain Spc7 PF08317.11 CDJ87963.1 - 0.28 10.0 4.3 0.92 8.3 4.3 2.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Cyt-b5 PF00173.28 CDJ87964.1 - 1.2e-23 83.0 0.0 3e-23 81.7 0.1 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.24 CDJ87964.1 - 7.7e-14 51.8 0.0 1.4e-12 47.8 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CDJ87964.1 - 1.9e-13 51.0 0.0 3.3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CDJ87964.1 - 0.00066 19.8 0.0 0.068 13.3 0.0 2.5 1 1 0 2 2 2 1 Ferric reductase NAD binding domain EF-hand_1 PF00036.32 CDJ87965.1 - 1.4e-28 96.3 11.2 3.6e-06 26.1 0.0 5.8 5 1 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 CDJ87965.1 - 2.9e-26 91.7 3.9 3.7e-13 49.7 0.0 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CDJ87965.1 - 1.2e-24 84.1 4.1 1.3e-05 24.7 0.0 5.3 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.6 CDJ87965.1 - 2.4e-23 81.7 3.3 2e-11 43.6 0.0 4.0 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CDJ87965.1 - 2.6e-20 70.9 7.1 3e-05 23.3 0.0 4.9 5 0 0 5 5 5 4 EF hand EF-hand_9 PF14658.6 CDJ87965.1 - 0.0048 17.2 0.0 5.7 7.3 0.0 2.9 2 1 1 3 3 3 2 EF-hand domain GUN4 PF05419.12 CDJ87965.1 - 0.012 15.7 0.0 0.96 9.5 0.0 2.1 2 0 0 2 2 2 0 GUN4-like SPARC_Ca_bdg PF10591.9 CDJ87965.1 - 0.02 15.2 0.3 3.7 7.9 0.1 3.0 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 CDJ87965.1 - 0.023 14.9 1.1 0.47 10.7 0.3 2.8 2 1 0 2 2 2 0 Dockerin type I domain WWE PF02825.20 CDJ87965.1 - 0.069 13.7 0.0 4 8.1 0.0 2.3 2 0 0 2 2 2 0 WWE domain Guanylate_kin PF00625.21 CDJ87966.1 - 1.4e-38 132.4 0.0 2.2e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase SH3_1 PF00018.28 CDJ87966.1 - 0.005 16.4 0.0 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 SH3 domain PDZ PF00595.24 CDJ87966.1 - 0.0067 16.8 0.2 0.02 15.2 0.2 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ87966.1 - 0.0091 16.3 0.2 0.031 14.6 0.2 1.9 1 0 0 1 1 1 1 PDZ domain SH3_2 PF07653.17 CDJ87966.1 - 0.01 15.5 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Imm9 PF15587.6 CDJ87967.1 - 0.071 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 9 AMP-binding PF00501.28 CDJ87968.1 - 8.4e-86 288.2 0.0 2.5e-51 174.6 0.0 2.5 2 1 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 CDJ87968.1 - 1.3e-20 74.2 0.4 3e-20 73.1 0.4 1.6 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.12 CDJ87968.1 - 0.00052 20.0 1.5 0.001 19.0 0.1 2.0 2 0 0 2 2 2 1 Gas vesicle protein G C2 PF00168.30 CDJ87969.1 - 9.9e-11 41.9 0.3 8.5e-10 38.8 0.0 2.6 3 0 0 3 3 3 1 C2 domain YmgB PF10798.8 CDJ87969.1 - 0.031 14.1 0.3 0.1 12.4 0.3 1.8 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR DUF3376 PF11856.8 CDJ87969.1 - 0.21 10.6 0.1 0.38 9.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) GlutR_dimer PF00745.20 CDJ87969.1 - 0.24 11.8 3.7 11 6.6 0.2 3.2 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain Ig_3 PF13927.6 CDJ87971.1 - 4.6e-06 27.1 0.9 0.0039 17.8 0.4 2.8 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 CDJ87971.1 - 0.00033 20.7 0.1 0.75 9.9 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 CDJ87971.1 - 0.019 15.1 2.0 0.042 14.0 0.6 2.1 2 1 0 2 2 2 0 Immunoglobulin domain Ig_2 PF13895.6 CDJ87971.1 - 0.071 13.5 2.5 0.51 10.7 1.9 2.6 2 2 1 3 3 3 0 Immunoglobulin domain Ribosomal_S8e PF01201.22 CDJ87972.1 - 1.6e-51 174.0 0.6 1.9e-51 173.8 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e NMD3 PF04981.13 CDJ87973.1 - 2.9e-75 252.9 6.5 4e-75 252.4 6.5 1.2 1 0 0 1 1 1 1 NMD3 family DUF3825 PF12873.7 CDJ87973.1 - 0.038 13.4 0.1 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3825) Nif11 PF07862.11 CDJ87973.1 - 0.072 13.4 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 Nif11 domain DZR PF12773.7 CDJ87973.1 - 1.2 9.3 8.2 3.1 7.9 3.1 2.7 2 0 0 2 2 2 0 Double zinc ribbon SdiA-regulated PF06977.11 CDJ87974.1 - 0.071 12.3 0.0 1.2 8.3 0.0 2.5 2 0 0 2 2 2 0 SdiA-regulated VWA_2 PF13519.6 CDJ87975.1 - 0.061 14.0 0.3 0.23 12.1 0.3 2.1 1 0 0 1 1 1 0 von Willebrand factor type A domain TssR PF17643.1 CDJ87975.1 - 0.087 10.8 0.5 0.14 10.1 0.5 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssR Peptidase_M1 PF01433.20 CDJ87975.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M1 domain EGF_2 PF07974.13 CDJ87975.1 - 0.2 12.1 34.8 0.048 14.0 0.8 4.4 4 0 0 4 4 4 0 EGF-like domain Laminin_EGF PF00053.24 CDJ87976.1 - 0.27 11.4 10.5 0.87 9.8 2.9 2.4 1 1 1 2 2 2 0 Laminin EGF domain EGF_2 PF07974.13 CDJ87976.1 - 1.9 9.0 14.2 0.12 12.7 4.0 2.5 2 0 0 2 2 2 0 EGF-like domain Ground-like PF04155.18 CDJ87977.1 - 5.4e-19 68.6 1.9 1e-18 67.7 1.9 1.5 1 0 0 1 1 1 1 Ground-like domain PolyA_pol_RNAbd PF12627.7 CDJ87977.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A zf-C4 PF00105.18 CDJ87979.1 - 4.8e-29 100.6 14.1 4.8e-29 100.6 14.1 2.2 3 0 0 3 3 3 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ87979.1 - 7.1e-18 64.9 0.1 1.5e-17 63.9 0.1 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor CKS PF01111.19 CDJ87982.1 - 1.4e-36 124.5 1.6 1.7e-36 124.3 1.6 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit MAGI_u1 PF16663.5 CDJ87983.1 - 0.021 14.9 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 Unstructured region on MAGI TetR_C_5 PF08360.11 CDJ87983.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 QacR-like protein, C-terminal region DUF4345 PF14248.6 CDJ87983.1 - 0.16 11.9 7.7 0.024 14.5 2.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4345) Wzy_C PF04932.15 CDJ87983.1 - 3.2 7.4 8.2 9.1 5.9 8.2 1.8 1 1 0 1 1 1 0 O-Antigen ligase UCH PF00443.29 CDJ87985.1 - 2.5e-45 155.0 0.1 5.7e-45 153.8 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ87985.1 - 2e-09 37.5 0.5 8.3e-09 35.5 0.5 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Syntaxin_2 PF14523.6 CDJ87985.1 - 0.087 13.2 0.3 2.6 8.5 0.1 3.0 3 0 0 3 3 3 0 Syntaxin-like protein Bin3 PF06859.12 CDJ87986.1 - 4.1e-41 140.0 0.0 7.8e-41 139.1 0.0 1.5 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.6 CDJ87986.1 - 1e-09 38.5 0.0 1.6e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ87986.1 - 1.4e-09 37.9 0.0 1.4e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ87986.1 - 2.9e-09 37.5 0.0 4.3e-06 27.3 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ87986.1 - 2.2e-08 34.8 0.0 1.1e-07 32.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ87986.1 - 8.9e-08 32.7 0.0 6.6e-06 26.7 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CDJ87986.1 - 1e-05 25.1 0.0 2.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CDJ87986.1 - 8.3e-05 22.2 0.0 0.0017 17.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.19 CDJ87986.1 - 0.00043 20.1 0.0 0.011 15.5 0.0 2.4 3 0 0 3 3 3 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 CDJ87986.1 - 0.0028 17.6 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CDJ87986.1 - 0.0048 16.4 0.0 0.022 14.2 0.0 1.9 1 1 0 2 2 2 1 Putative methyltransferase Methyltransf_32 PF13679.6 CDJ87986.1 - 0.0066 16.4 0.4 0.033 14.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 CDJ87986.1 - 0.015 14.6 0.0 3.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 CDJ87986.1 - 0.16 11.3 0.0 0.44 9.8 0.0 1.7 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family zf-C2H2_4 PF13894.6 CDJ87987.1 - 3.5e-08 33.6 21.2 0.091 13.6 0.2 6.8 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CDJ87987.1 - 5.5e-08 32.8 21.9 0.0026 18.1 0.2 6.6 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_3 PF13878.6 CDJ87987.1 - 0.022 14.6 5.1 0.61 10.0 0.1 3.9 4 0 0 4 4 4 0 zinc-finger of acetyl-transferase ESCO zf-H2C2_5 PF13909.6 CDJ87987.1 - 0.23 11.3 0.1 0.23 11.3 0.1 3.5 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 CDJ87987.1 - 0.26 11.6 3.1 10 6.5 0.0 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding CpXC PF14353.6 CDJ87987.1 - 0.27 11.3 6.0 14 5.7 0.0 4.2 2 1 3 5 5 5 0 CpXC protein zf-met PF12874.7 CDJ87987.1 - 0.42 11.1 0.1 0.42 11.1 0.1 4.6 4 1 0 4 4 4 0 Zinc-finger of C2H2 type Nudix_N_2 PF14803.6 CDJ87987.1 - 0.43 10.5 9.8 12 5.9 1.7 4.2 4 0 0 4 4 4 0 Nudix N-terminal zf_C2H2_ZHX PF18387.1 CDJ87987.1 - 0.48 10.1 12.9 0.78 9.4 0.4 3.8 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain FYVE PF01363.21 CDJ87987.1 - 2.1 8.5 7.9 4.3 7.5 4.7 2.9 2 1 0 2 2 2 0 FYVE zinc finger zf-Di19 PF05605.12 CDJ87987.1 - 7.9 6.9 20.7 0.5 10.7 0.3 5.0 5 1 1 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding Arrestin_N PF00339.29 CDJ87988.1 - 1.6e-21 76.9 0.0 6.4e-21 74.9 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CDJ87988.1 - 7.7e-14 52.3 0.6 2.6e-13 50.6 0.3 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 CDJ87988.1 - 0.0099 15.1 0.1 0.39 9.8 0.0 2.3 2 0 0 2 2 2 2 Rgp1 DUF4133 PF13571.6 CDJ87990.1 - 0.34 11.3 5.4 0.2 12.0 3.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4133) Ig_3 PF13927.6 CDJ87991.1 - 1.9e-14 54.0 0.0 3.7e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 CDJ87991.1 - 1.9e-13 50.3 0.0 2.9e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 CDJ87991.1 - 6.6e-11 42.4 0.0 1.4e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CDJ87991.1 - 6.9e-09 35.8 0.0 1.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 CDJ87991.1 - 0.00051 20.2 0.1 0.0016 18.6 0.1 1.8 1 1 0 1 1 1 1 Immunoglobulin V-set domain C1-set PF07654.15 CDJ87991.1 - 0.03 14.7 0.1 0.051 14.0 0.1 1.4 1 0 0 1 1 1 0 Immunoglobulin C1-set domain C2-set_2 PF08205.12 CDJ87991.1 - 0.064 13.3 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Astacin PF01400.24 CDJ87993.1 - 1e-59 201.4 0.6 1.6e-59 200.7 0.6 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) AMP-binding PF00501.28 CDJ87993.1 - 3e-31 108.5 0.0 5.4e-31 107.6 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ87993.1 - 1.5e-14 54.7 0.0 3.2e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LRR_8 PF13855.6 CDJ87994.1 - 2.9e-08 33.3 16.9 0.015 15.0 0.1 4.1 2 1 2 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 CDJ87994.1 - 4.6e-08 32.8 9.1 3.9e-07 29.7 0.4 3.1 1 1 1 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 CDJ87994.1 - 1.3e-06 27.9 14.4 0.08 13.0 0.0 6.5 6 1 1 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 CDJ87994.1 - 1.4e-06 28.5 24.9 0.17 12.4 0.0 5.1 4 1 0 5 5 5 3 Leucine Rich repeats (2 copies) Ubiquitin_2 PF14560.6 CDJ87994.1 - 0.014 15.9 0.0 0.054 13.9 0.0 2.1 1 0 0 1 1 1 0 Ubiquitin-like domain ubiquitin PF00240.23 CDJ87994.1 - 0.05 13.3 0.3 0.84 9.4 0.0 2.9 3 0 0 3 3 3 0 Ubiquitin family DUF1207 PF06727.11 CDJ87994.1 - 0.17 10.8 0.1 2.2 7.1 0.0 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1207) LRR_1 PF00560.33 CDJ87994.1 - 1.1 10.1 16.6 0.43 11.3 0.2 5.2 6 1 0 6 6 6 0 Leucine Rich Repeat Lung_7-TM_R PF06814.13 CDJ87995.1 - 6.4e-07 28.9 3.0 7.6e-07 28.7 3.0 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor 7tm_3 PF00003.22 CDJ87996.1 - 1.6e-45 155.7 27.6 2.7e-45 155.0 27.6 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 CDJ87996.1 - 5.1e-30 104.8 0.0 7.3e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.14 CDJ87996.1 - 1.8e-10 40.6 14.0 4e-10 39.5 14.0 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR VIT1 PF01988.19 CDJ87996.1 - 0.31 10.9 8.9 0.25 11.2 0.3 2.9 2 1 1 3 3 3 0 VIT family Ribosomal_S3Ae PF01015.18 CDJ87997.1 - 4.2e-87 291.0 1.6 4.9e-87 290.7 1.6 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family AroM PF07302.11 CDJ87997.1 - 0.16 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 AroM protein Thioredoxin_6 PF13848.6 CDJ87999.1 - 6e-05 23.0 0.2 0.00048 20.1 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin PF00085.20 CDJ87999.1 - 0.022 14.8 0.0 0.06 13.3 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin CAP PF00188.26 CDJ88000.1 - 1.2e-19 71.4 1.6 1.5e-19 71.0 1.6 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ88000.1 - 0.11 12.8 2.3 0.45 10.8 2.3 2.2 1 1 0 1 1 1 0 Ancylostoma-associated secreted protein related Thioredoxin_6 PF13848.6 CDJ88001.1 - 0.0054 16.7 0.0 0.0071 16.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain DUF2847 PF11009.8 CDJ88001.1 - 0.0076 16.1 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) zf-C3HC4_3 PF13920.6 CDJ88002.1 - 0.00017 21.4 2.9 0.00031 20.5 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ88002.1 - 0.00071 19.5 3.8 0.0017 18.3 3.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CDJ88002.1 - 0.0024 17.7 4.2 0.0053 16.6 4.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ88002.1 - 0.0028 17.5 4.3 0.0062 16.4 4.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDJ88002.1 - 0.0034 17.2 4.6 0.0068 16.2 4.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CDJ88002.1 - 0.021 14.9 5.2 0.047 13.7 5.2 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 CDJ88002.1 - 0.085 13.2 0.9 0.24 11.7 0.9 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CDJ88002.1 - 0.3 11.5 4.8 0.7 10.3 4.8 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 CDJ88002.1 - 0.49 10.6 3.7 1.3 9.3 3.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Vip3A_N PF12495.8 CDJ88002.1 - 9.2 6.1 9.7 6.2 6.7 0.2 3.0 2 0 0 2 2 2 0 Vegetative insecticide protein 3A N terminal RRM_1 PF00076.22 CDJ88003.1 - 7.4e-28 96.2 0.0 2e-14 53.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ88003.1 - 1.5e-07 31.5 0.1 0.0012 18.9 0.0 3.3 3 1 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.11 CDJ88003.1 - 0.002 18.2 0.0 0.98 9.5 0.0 2.7 1 1 1 2 2 2 2 RNA binding motif RRM_5 PF13893.6 CDJ88003.1 - 0.0043 16.6 0.0 0.012 15.2 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1415 PF07209.12 CDJ88003.1 - 0.017 14.9 0.6 0.038 13.7 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1415) DUF4283 PF14111.6 CDJ88003.1 - 0.017 14.6 0.0 0.1 12.1 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4283) UTP15_C PF09384.10 CDJ88003.1 - 0.055 13.2 2.1 0.06 13.0 0.8 1.8 2 0 0 2 2 2 0 UTP15 C terminal DUF1497 PF07384.11 CDJ88003.1 - 0.47 10.9 4.1 0.23 11.9 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1497) NAPRTase PF04095.16 CDJ88004.1 - 4.7e-65 219.6 0.0 8.7e-65 218.7 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF5598 PF18127.1 CDJ88004.1 - 5.9e-39 132.5 0.1 1.7e-38 131.0 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5598) AdoMet_MTase PF07757.13 CDJ88004.1 - 5.1e-35 120.2 0.0 1.2e-34 119.0 0.0 1.6 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MetW PF07021.12 CDJ88004.1 - 0.0098 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 CDJ88004.1 - 0.094 12.7 0.0 0.87 9.6 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ88004.1 - 0.1 12.4 0.0 0.35 10.7 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain RF-1 PF00472.20 CDJ88005.1 - 1.7e-18 66.6 0.8 2.3e-18 66.2 0.8 1.2 1 0 0 1 1 1 1 RF-1 domain Kinesin PF00225.23 CDJ88006.1 - 5e-110 367.5 1.3 1.7e-109 365.8 1.3 1.9 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ88006.1 - 1.6e-27 96.3 0.1 1.6e-27 96.3 0.1 2.8 3 1 0 3 3 3 1 Microtubule binding TMF_DNA_bd PF12329.8 CDJ88006.1 - 0.01 15.8 15.6 0.01 15.8 15.6 5.6 4 3 2 6 6 6 0 TATA element modulatory factor 1 DNA binding HALZ PF02183.18 CDJ88006.1 - 3.8 7.8 13.2 6.1 7.2 0.6 4.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper LIM PF00412.22 CDJ88008.1 - 7.5e-29 99.7 17.5 2.4e-16 59.7 1.0 2.4 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 CDJ88008.1 - 1.8e-19 69.3 0.7 1.8e-19 69.3 0.7 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CDJ88008.1 - 0.00045 20.1 0.1 0.00094 19.0 0.1 1.6 1 1 0 1 1 1 1 Homeobox KN domain TNFR_c6 PF00020.18 CDJ88008.1 - 9.9 6.7 23.2 5.8 7.4 0.3 4.5 4 0 0 4 4 4 0 TNFR/NGFR cysteine-rich region EB PF01683.18 CDJ88009.1 - 7.3e-81 266.3 229.8 2.9e-14 53.1 12.8 12.6 9 2 2 11 11 11 8 EB module Lustrin_cystein PF14625.6 CDJ88009.1 - 0.00025 21.3 8.9 0.00025 21.3 8.9 14.5 7 4 6 13 13 13 4 Lustrin, cysteine-rich repeated domain EGF_3 PF12947.7 CDJ88009.1 - 0.012 15.8 8.6 0.012 15.8 8.6 13.2 12 2 1 13 13 13 0 EGF domain Rcd1 PF04078.13 CDJ88010.1 - 0.19 11.0 0.1 0.25 10.6 0.1 1.1 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like RhoGAP PF00620.27 CDJ88011.1 - 5.2e-48 162.7 0.2 1.5e-47 161.2 0.2 1.8 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 CDJ88011.1 - 4.4e-08 33.6 0.2 1.2e-07 32.2 0.2 1.8 1 0 0 1 1 1 1 PH domain WW PF00397.26 CDJ88011.1 - 3.3e-06 27.1 0.5 3.3e-06 27.1 0.5 1.8 2 0 0 2 2 2 1 WW domain PH_9 PF15410.6 CDJ88011.1 - 6.4e-06 26.5 0.1 1.5e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain DUF1708 PF08101.11 CDJ88011.1 - 0.0076 15.5 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) Pox_vIL-18BP PF05566.12 CDJ88011.1 - 0.018 15.2 0.0 0.056 13.7 0.0 1.8 1 0 0 1 1 1 0 Orthopoxvirus interleukin 18 binding protein Fra10Ac1 PF09725.9 CDJ88011.1 - 0.052 13.6 0.3 0.88 9.7 0.3 2.3 1 1 0 1 1 1 0 Folate-sensitive fragile site protein Fra10Ac1 Metallophos PF00149.28 CDJ88012.1 - 9e-33 114.5 0.0 1.4e-32 113.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ndc1_Nup PF09531.10 CDJ88012.1 - 0.23 10.1 0.4 0.29 9.8 0.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4680 PF15730.5 CDJ88012.1 - 4 7.8 8.1 0.21 11.9 1.5 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4680) TTR-52 PF01060.23 CDJ88013.1 - 5.5e-05 23.8 0.0 7.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Transthyretin-like family DUF1372 PF07116.11 CDJ88013.1 - 0.021 15.0 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1372) FERM_C PF09380.10 CDJ88014.1 - 1.6e-20 73.3 0.2 3.2e-20 72.3 0.2 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 CDJ88014.1 - 3.6e-20 72.5 0.3 7.9e-20 71.4 0.3 1.6 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 CDJ88014.1 - 2e-15 56.4 0.5 7.4e-14 51.4 0.0 2.8 3 0 0 3 3 3 1 FERM N-terminal domain FA PF08736.11 CDJ88014.1 - 3.9e-11 42.8 5.9 3.9e-11 42.8 5.9 2.1 2 0 0 2 2 2 1 FERM adjacent (FA) 7TM_GPCR_Sra PF02117.16 CDJ88017.1 - 3.6e-20 72.1 26.4 4.6e-20 71.7 26.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sra 7TM_GPCR_Srab PF10292.9 CDJ88017.1 - 4.4e-16 58.7 25.4 5.1e-16 58.5 25.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor DUF1129 PF06570.11 CDJ88017.1 - 5.5 6.4 18.5 1.8 8.0 1.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) Rav1p_C PF12234.8 CDJ88019.1 - 2.6e-69 234.3 9.0 1e-65 222.4 9.2 3.4 2 1 0 2 2 2 2 RAVE protein 1 C terminal QueH PF02677.14 CDJ88019.1 - 0.019 15.1 0.5 0.035 14.2 0.5 1.4 1 0 0 1 1 1 0 Epoxyqueuosine reductase QueH Aldedh PF00171.22 CDJ88021.1 - 1.8e-89 300.4 0.0 2.1e-89 300.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 CDJ88021.1 - 1.4e-05 24.4 0.0 3.3e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) NOG1_N PF17835.1 CDJ88021.1 - 0.021 14.8 0.0 0.91 9.5 0.1 2.9 3 0 0 3 3 3 0 NOG1 N-terminal helical domain DUF917 PF06032.12 CDJ88021.1 - 0.062 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF917) Aldedh PF00171.22 CDJ88022.1 - 4.4e-81 272.7 0.0 5.3e-81 272.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF917 PF06032.12 CDJ88022.1 - 0.01 14.7 0.1 0.019 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF917) Ion_trans_2 PF07885.16 CDJ88024.1 - 5.2e-28 96.8 17.1 6.5e-16 58.1 2.8 3.2 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CDJ88024.1 - 5.3e-10 38.9 3.0 3.3e-05 23.2 2.0 2.2 1 1 1 2 2 2 2 Ion transport protein Sigma_reg_N PF13800.6 CDJ88024.1 - 1.6 9.0 5.7 21 5.5 0.2 3.3 3 0 0 3 3 3 0 Sigma factor regulator N-terminal PCI PF01399.27 CDJ88025.1 - 5.8e-18 65.3 0.0 2.6e-17 63.3 0.0 2.2 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 CDJ88025.1 - 7.1e-10 38.8 1.6 1.7e-09 37.6 1.6 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain DUF1922 PF09082.10 CDJ88025.1 - 0.067 13.5 1.5 5.3 7.4 0.1 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1922) Uroplakin_II PF07353.12 CDJ88026.1 - 0.16 11.5 0.1 0.21 11.1 0.1 1.1 1 0 0 1 1 1 0 Uroplakin II FSA_C PF10479.9 CDJ88027.1 - 0.039 12.1 4.8 0.05 11.8 4.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Yip1 PF04893.17 CDJ88028.1 - 7.1e-12 45.4 20.7 8.8e-12 45.1 20.0 1.5 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 CDJ88028.1 - 0.019 14.8 11.5 0.027 14.3 11.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) EMP24_GP25L PF01105.24 CDJ88029.1 - 7.8e-15 55.3 0.3 1e-14 54.9 0.3 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RT_RNaseH_2 PF17919.1 CDJ88030.1 - 2.6e-35 120.5 0.1 4.2e-35 119.8 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ88030.1 - 5.3e-27 94.2 0.1 8.3e-27 93.5 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ88030.1 - 7.2e-17 61.7 0.0 1.4e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CDJ88030.1 - 0.049 13.6 0.0 0.075 13.0 0.0 1.2 1 0 0 1 1 1 0 Pao retrotransposon peptidase Peptidase_M3_N PF08439.10 CDJ88030.1 - 0.16 12.2 0.2 0.78 10.1 0.1 2.1 2 0 0 2 2 2 0 Oligopeptidase F Med2 PF11214.8 CDJ88030.1 - 0.18 12.0 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit 2 DUF3245 PF11595.8 CDJ88030.1 - 0.22 12.0 0.0 0.35 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Astacin PF01400.24 CDJ88031.1 - 8e-57 191.9 0.0 1.3e-56 191.3 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 CDJ88031.1 - 0.0026 17.4 0.1 0.0056 16.3 0.1 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CDJ88031.1 - 0.011 15.6 0.3 0.67 9.8 0.2 2.5 1 1 1 2 2 2 0 Matrixin Reprolysin_5 PF13688.6 CDJ88031.1 - 0.017 15.3 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 Metallo-peptidase family M12 CUB PF00431.20 CDJ88031.1 - 0.092 13.1 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 CUB domain DUF4953 PF16313.5 CDJ88031.1 - 0.13 11.4 0.1 0.22 10.7 0.1 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M57 PF12388.8 CDJ88031.1 - 0.15 11.7 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase TDP43_N PF18694.1 CDJ88032.1 - 3.1e-25 87.8 0.0 5.4e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain RRM_1 PF00076.22 CDJ88032.1 - 1.1e-13 50.8 1.7 2.1e-10 40.3 0.3 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acyl-CoA_dh_2 PF08028.11 CDJ88034.1 - 0.0018 18.6 0.7 0.0018 18.6 0.7 3.9 1 1 3 4 4 4 1 Acyl-CoA dehydrogenase, C-terminal domain RPAP1_C PF08620.10 CDJ88034.1 - 5.6 7.1 6.9 0.65 10.1 1.8 2.1 2 0 0 2 2 2 0 RPAP1-like, C-terminal TB2_DP1_HVA22 PF03134.19 CDJ88035.1 - 1.2e-23 82.9 5.8 1.2e-23 82.9 5.8 1.7 2 0 0 2 2 2 1 TB2/DP1, HVA22 family PI-PLC-X PF00388.19 CDJ88036.1 - 9.8e-33 112.8 0.0 1.8e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CDJ88036.1 - 1e-27 96.7 0.0 2.1e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 CDJ88036.1 - 6e-16 58.7 0.0 1.7e-15 57.2 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 CDJ88036.1 - 2.4e-15 56.7 0.0 6.9e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 C2 domain PH_12 PF16457.5 CDJ88036.1 - 1.1e-14 55.1 0.0 2.4e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_14 PF17787.1 CDJ88036.1 - 0.00031 20.6 0.0 0.00072 19.4 0.0 1.6 1 0 0 1 1 1 1 PH domain EF-hand_7 PF13499.6 CDJ88036.1 - 0.08 13.4 0.1 1.1 9.8 0.0 2.9 2 1 0 2 2 2 0 EF-hand domain pair DUF572 PF04502.13 CDJ88037.1 - 3.1e-78 263.7 7.4 3.8e-78 263.4 7.4 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) RRN3 PF05327.11 CDJ88038.1 - 3 6.3 4.6 4.5 5.7 4.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Exo_endo_phos_2 PF14529.6 CDJ88039.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase TTR-52 PF01060.23 CDJ88040.1 - 2.8e-23 82.4 0.0 3.3e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Transthyretin-like family DUF4198 PF10670.9 CDJ88040.1 - 6.2e-06 26.7 0.1 7.9e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4198) bMG3 PF11974.8 CDJ88040.1 - 0.0023 17.9 0.0 0.0027 17.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial alpha-2-macroglobulin MG3 domain CarboxypepD_reg PF13620.6 CDJ88040.1 - 0.0038 17.5 0.0 0.0049 17.1 0.0 1.2 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Transthyretin PF00576.21 CDJ88040.1 - 0.014 16.1 0.0 0.017 15.8 0.0 1.2 1 0 0 1 1 1 0 HIUase/Transthyretin family PdxJ PF03740.13 CDJ88040.1 - 0.24 10.5 0.0 0.28 10.3 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ fn3 PF00041.21 CDJ88041.1 - 4.3e-05 23.8 0.3 0.0046 17.3 0.0 2.8 2 0 0 2 2 2 2 Fibronectin type III domain Glyco_hydro_15 PF00723.21 CDJ88042.1 - 5.6e-16 58.4 0.0 6.8e-16 58.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 BET PF17035.5 CDJ88042.1 - 0.023 14.9 0.7 0.063 13.5 0.1 2.0 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation Glyco_hydro_15 PF00723.21 CDJ88043.1 - 3e-75 253.7 0.0 4e-75 253.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Prp18 PF02840.15 CDJ88044.1 - 7.6e-52 175.2 1.8 1.5e-51 174.2 0.1 2.1 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 CDJ88044.1 - 1.4e-11 43.7 1.6 3e-11 42.7 1.6 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like DUF29 PF01724.16 CDJ88044.1 - 0.042 14.1 2.5 5.6 7.2 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF29 EZH2_WD-Binding PF11616.8 CDJ88044.1 - 0.082 13.0 0.0 0.83 9.8 0.0 2.4 2 0 0 2 2 2 0 WD repeat binding protein EZH2 Kri1 PF05178.12 CDJ88044.1 - 0.29 11.7 12.2 0.069 13.7 7.1 2.4 2 1 0 2 2 2 0 KRI1-like family polyprenyl_synt PF00348.17 CDJ88045.1 - 3.4e-62 209.8 0.0 6.4e-62 208.9 0.0 1.5 1 0 0 1 1 1 1 Polyprenyl synthetase RRM_1 PF00076.22 CDJ88045.1 - 4.5e-27 93.7 0.7 4.1e-18 65.0 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_14 PF13428.6 CDJ88045.1 - 2.1e-05 25.0 1.6 2.8 9.0 0.0 5.3 4 0 0 4 4 4 2 Tetratricopeptide repeat NRDE-2 PF08424.10 CDJ88045.1 - 0.00035 19.8 9.0 0.61 9.2 0.3 4.8 2 2 3 5 5 5 2 NRDE-2, necessary for RNA interference Nup35_RRM_2 PF14605.6 CDJ88045.1 - 0.018 15.0 0.1 0.21 11.6 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Suf PF05843.14 CDJ88045.1 - 8.3 6.3 15.8 18 5.2 1.1 3.0 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) DUF155 PF02582.14 CDJ88046.1 - 1.4e-32 113.2 0.1 3e-32 112.1 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 E1_dh PF00676.20 CDJ88047.1 - 7.3e-89 297.7 0.2 2.2e-86 289.5 0.2 2.1 1 1 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.21 CDJ88047.1 - 3.5e-06 26.2 0.3 6.4e-06 25.3 0.2 1.5 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.6 CDJ88047.1 - 0.00028 20.2 0.0 0.00092 18.5 0.0 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 CDJ88047.1 - 0.004 17.0 0.2 0.014 15.2 0.2 1.8 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CBFD_NFYB_HMF PF00808.23 CDJ88048.1 - 2.5e-16 59.7 0.0 4.4e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDJ88048.1 - 0.002 18.5 0.1 0.0047 17.3 0.0 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-W PF15510.6 CDJ88048.1 - 0.049 13.8 0.2 0.23 11.7 0.1 1.9 2 0 0 2 2 2 0 CENP-W protein Dzip-like_N PF13815.6 CDJ88048.1 - 0.12 12.3 1.0 0.32 11.0 0.7 1.7 1 1 1 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal GDA1_CD39 PF01150.17 CDJ88049.1 - 9.8e-133 442.9 0.0 1.6e-132 442.2 0.0 1.2 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Pkinase PF00069.25 CDJ88049.1 - 1.4e-61 208.2 0.0 3.3e-61 207.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain CNH PF00780.22 CDJ88049.1 - 9.2e-57 192.7 0.0 1.3e-56 192.2 0.0 1.2 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.17 CDJ88049.1 - 1.4e-43 149.1 0.0 2.5e-43 148.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ88049.1 - 6.1e-05 22.0 0.0 0.00019 20.4 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CDJ88049.1 - 0.0072 15.7 0.0 0.015 14.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 CDJ88049.1 - 0.08 12.6 0.2 0.32 10.6 0.1 2.0 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CDJ88049.1 - 0.092 11.7 0.9 0.15 11.0 0.1 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Shugoshin_C PF07557.11 CDJ88051.1 - 2.1e-07 30.6 3.2 4e-07 29.7 3.2 1.5 1 0 0 1 1 1 1 Shugoshin C terminus Tex_N PF09371.10 CDJ88052.1 - 0.0016 18.1 1.7 0.026 14.2 0.5 2.6 2 0 0 2 2 2 1 Tex-like protein N-terminal domain MCD_N PF17408.2 CDJ88052.1 - 0.056 13.6 1.1 12 6.1 0.0 3.4 3 0 0 3 3 3 0 Malonyl-CoA decarboxylase N-terminal domain VAPB_antitox PF02697.14 CDJ88052.1 - 0.058 14.2 0.8 2 9.3 0.0 3.3 3 0 0 3 3 3 0 Putative antitoxin DUF4815 PF16075.5 CDJ88052.1 - 0.068 11.5 0.0 0.098 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4815) TSC22 PF01166.18 CDJ88052.1 - 0.11 12.8 0.6 0.46 10.8 0.6 2.1 1 0 0 1 1 1 0 TSC-22/dip/bun family Pro_dh PF01619.18 CDJ88052.1 - 0.11 12.0 0.6 0.33 10.4 0.0 1.8 2 0 0 2 2 2 0 Proline dehydrogenase Pkinase PF00069.25 CDJ88053.1 - 3e-37 128.4 0.0 7.1e-37 127.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ88053.1 - 1e-14 54.5 0.0 3.2e-14 52.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ88053.1 - 9.1e-05 21.9 0.8 0.00016 21.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CDJ88053.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family EF-hand_4 PF12763.7 CDJ88055.1 - 1.7e-43 146.8 0.0 2.7e-19 69.0 0.0 3.6 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CDJ88055.1 - 2.5e-10 39.2 0.2 0.0091 15.5 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CDJ88055.1 - 9.8e-08 31.3 0.3 0.59 10.2 0.0 4.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 CDJ88055.1 - 7.6e-07 29.5 0.0 0.0074 16.7 0.0 3.6 3 1 1 4 4 4 3 EF-hand domain pair DUF2968 PF11180.8 CDJ88055.1 - 0.0029 17.3 11.7 0.0029 17.3 11.7 3.1 1 1 2 3 3 3 1 Protein of unknown function (DUF2968) ADIP PF11559.8 CDJ88055.1 - 0.053 13.6 31.0 1 9.4 10.2 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding MA-Mit PF09245.10 CDJ88055.1 - 0.093 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Mycoplasma arthritidis-derived mitogen ATG16 PF08614.11 CDJ88055.1 - 0.098 12.9 41.7 0.13 12.4 11.2 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 CDJ88055.1 - 0.13 12.8 36.0 0.053 14.0 10.1 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region FPP PF05911.11 CDJ88055.1 - 0.24 9.5 22.7 0.35 9.0 22.7 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil EF-hand_5 PF13202.6 CDJ88055.1 - 0.3 10.7 1.9 5.9 6.6 0.1 2.6 2 0 0 2 2 2 0 EF hand DUF3450 PF11932.8 CDJ88055.1 - 0.33 10.2 31.3 0.91 8.8 13.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Rab5-bind PF09311.11 CDJ88055.1 - 0.37 10.1 30.2 3.4 7.0 17.3 2.3 1 1 1 2 2 2 0 Rabaptin-like protein GAS PF13851.6 CDJ88055.1 - 1.6 8.0 32.3 0.5 9.7 9.1 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding APH PF01636.23 CDJ88055.1 - 1.6 8.6 6.9 3.7 7.4 6.9 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family LMBR1 PF04791.16 CDJ88055.1 - 2.5 6.9 11.2 3.7 6.3 11.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Atg14 PF10186.9 CDJ88055.1 - 2.8 6.9 18.7 4.7 6.2 18.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 T3SSipB PF16535.5 CDJ88055.1 - 3.4 8.1 24.6 2.6 8.5 18.4 2.5 1 1 1 2 2 2 0 Type III cell invasion protein SipB CENP-F_leu_zip PF10473.9 CDJ88055.1 - 7.5 6.6 31.9 52 3.9 17.2 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 XhlA PF10779.9 CDJ88055.1 - 8 6.8 16.2 7.1 6.9 0.9 3.6 2 1 1 3 3 3 0 Haemolysin XhlA Peptidase_S10 PF00450.22 CDJ88056.1 - 1.2e-129 433.5 0.4 1.6e-129 433.0 0.4 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase RRM_7 PF16367.5 CDJ88056.1 - 1.1e-37 128.0 0.0 2.8e-35 120.3 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif CEBP_ZZ PF16366.5 CDJ88056.1 - 1.1e-20 73.5 8.9 3e-20 72.2 8.9 1.8 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 CDJ88056.1 - 2.6e-12 46.4 0.0 0.0007 19.4 0.0 4.2 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HAGH_C PF16123.5 CDJ88057.1 - 2.7e-28 98.3 0.1 6.4e-28 97.1 0.1 1.7 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus SPRY PF00622.28 CDJ88057.1 - 5.8e-11 42.6 0.2 2.1e-06 27.9 0.0 2.5 2 0 0 2 2 2 2 SPRY domain Lactamase_B PF00753.27 CDJ88057.1 - 2e-10 41.0 4.7 8.4e-10 39.0 4.7 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CDJ88057.1 - 3.3e-05 23.5 0.2 9.5e-05 22.0 0.2 1.9 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PHD PF00628.29 CDJ88057.1 - 0.001 18.9 7.5 0.003 17.4 7.5 1.9 1 0 0 1 1 1 1 PHD-finger RINGv PF12906.7 CDJ88057.1 - 5.8 7.1 6.4 8.7 6.6 1.9 2.6 2 0 0 2 2 2 0 RING-variant domain DS PF01916.17 CDJ88058.1 - 3.9e-125 416.9 0.0 4.4e-125 416.7 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Carbam_trans_N PF02543.15 CDJ88058.1 - 0.18 11.4 0.1 0.27 10.8 0.1 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus Ly-6_related PF06579.12 CDJ88059.1 - 7.8e-05 22.9 0.1 7.8e-05 22.9 0.1 3.0 2 1 0 2 2 2 1 Caenorhabditis elegans ly-6-related protein QVR PF17064.5 CDJ88059.1 - 2.6 8.4 16.8 0.85 9.9 0.4 3.6 4 0 0 4 4 4 0 Sleepless protein Globin PF00042.22 CDJ88060.1 - 0.11 13.1 0.0 0.21 12.1 0.0 1.5 1 1 0 1 1 1 0 Globin RNase_T PF00929.24 CDJ88061.1 - 3.6e-15 56.9 0.0 1.3e-14 55.1 0.0 1.8 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.20 CDJ88061.1 - 0.00016 21.5 0.0 0.00047 19.9 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease Redoxin PF08534.10 CDJ88061.1 - 0.018 14.8 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Redoxin sCache_like PF16736.5 CDJ88061.1 - 0.1 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Single Cache-like Ribosomal_L10 PF00466.20 CDJ88062.1 - 7.9e-06 25.9 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Peptidase_S10 PF00450.22 CDJ88063.1 - 2e-129 432.7 0.4 2.3e-129 432.5 0.4 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S9 PF00326.21 CDJ88063.1 - 0.0069 15.9 0.1 1 8.8 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Carboxyl_trans PF01039.22 CDJ88063.1 - 0.098 11.3 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Carboxyl transferase domain Peptidase_S10 PF00450.22 CDJ88064.1 - 1.7e-44 152.9 0.0 8.5e-23 81.4 0.0 2.0 1 1 1 2 2 2 2 Serine carboxypeptidase Peptidase_S9 PF00326.21 CDJ88064.1 - 0.14 11.6 0.1 0.7 9.3 0.0 2.1 2 1 0 2 2 2 0 Prolyl oligopeptidase family Peripla_BP_6 PF13458.6 CDJ88064.1 - 0.16 11.6 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein Hydrolase_4 PF12146.8 CDJ88064.1 - 0.17 11.1 0.0 0.36 10.0 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S10 PF00450.22 CDJ88065.1 - 2e-20 73.6 0.0 2.4e-20 73.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peripla_BP_6 PF13458.6 CDJ88065.1 - 0.047 13.3 0.0 0.061 13.0 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein SNF2_N PF00176.23 CDJ88067.1 - 1.4e-08 33.9 2.2 7.5e-08 31.5 0.1 2.1 1 1 1 2 2 2 2 SNF2 family N-terminal domain RE_TdeIII PF09520.10 CDJ88069.1 - 0.18 11.4 5.6 0.2 11.3 5.6 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII Hyd_WA PF06462.12 CDJ88070.1 - 2.8e-27 94.4 29.7 3.5e-12 46.1 0.6 8.3 8 0 0 8 8 8 6 Propeller Pex24p PF06398.11 CDJ88070.1 - 7.8e-11 41.6 14.1 5.7e-06 25.6 0.9 2.2 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin GRAM PF02893.20 CDJ88070.1 - 0.066 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 GRAM domain ATP-synt_C PF00137.21 CDJ88071.1 - 2.9e-21 75.6 26.6 1.1e-13 51.3 8.7 2.9 3 0 0 3 3 3 2 ATP synthase subunit C DUF2530 PF10745.9 CDJ88071.1 - 4.8 7.5 10.7 0.86 9.9 0.7 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2530) Voltage_CLC PF00654.20 CDJ88072.1 - 7e-98 328.1 28.9 8.2e-98 327.9 24.7 2.0 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 CDJ88072.1 - 5.3e-18 65.2 0.2 6.6e-09 36.1 0.1 2.5 2 0 0 2 2 2 2 CBS domain SNAPc_SNAP43 PF09808.9 CDJ88073.1 - 1.6e-30 106.4 0.1 3.2e-30 105.5 0.0 1.5 2 0 0 2 2 2 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Ank_4 PF13637.6 CDJ88075.1 - 4.6e-18 65.3 3.9 6e-10 39.5 1.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ88075.1 - 3.1e-17 62.4 4.9 1.2e-09 38.2 1.6 2.5 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ88075.1 - 2.4e-16 60.1 0.7 4.1e-16 59.3 0.7 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ88075.1 - 3.3e-14 52.6 2.2 2e-05 24.8 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CDJ88075.1 - 6.9e-14 50.6 2.0 0.00025 21.2 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat B2-adapt-app_C PF09066.10 CDJ88075.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain Metallophos PF00149.28 CDJ88076.1 - 1.7e-19 71.1 0.0 1.9e-19 70.9 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDJ88076.1 - 6.8e-09 36.0 0.1 1.2e-08 35.2 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain PHD_4 PF16866.5 CDJ88077.1 - 0.037 14.1 1.3 0.037 14.1 1.3 2.0 2 0 0 2 2 2 0 PHD-finger DUF753 PF05444.12 CDJ88077.1 - 1.1 9.3 8.9 0.82 9.7 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF753) QVR PF17064.5 CDJ88077.1 - 5.4 7.3 7.9 12 6.2 7.9 1.7 1 1 0 1 1 1 0 Sleepless protein Serpin PF00079.20 CDJ88080.1 - 2.7e-87 293.5 2.1 3e-87 293.4 2.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 CDJ88082.1 - 5.2e-76 256.4 2.6 6.1e-76 256.1 2.6 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DNA_pol3_a_NII PF11490.8 CDJ88082.1 - 0.25 11.2 3.9 4.4 7.2 1.3 2.3 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II Serpin PF00079.20 CDJ88083.1 - 9.7e-45 153.5 6.8 1.8e-29 103.2 0.4 2.0 1 1 1 2 2 2 2 Serpin (serine protease inhibitor) WD40 PF00400.32 CDJ88084.1 - 1.6e-22 79.4 0.6 0.0032 18.3 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.8 CDJ88084.1 - 2.1e-06 26.7 1.5 0.053 12.2 0.0 3.3 2 1 1 3 3 3 3 Nucleoporin Nup120/160 WD40_like PF17005.5 CDJ88084.1 - 0.14 11.4 0.0 9 5.5 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain EGF_2 PF07974.13 CDJ88085.1 - 4.6e-06 26.9 48.1 0.16 12.4 4.9 5.4 5 0 0 5 5 5 5 EGF-like domain Laminin_EGF PF00053.24 CDJ88085.1 - 6.9e-06 26.1 42.4 0.18 12.0 4.7 5.2 1 1 4 5 5 5 3 Laminin EGF domain MAP17 PF15807.5 CDJ88085.1 - 0.0051 17.1 0.1 0.0084 16.3 0.1 1.3 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Protocadherin PF08374.11 CDJ88085.1 - 0.023 14.7 0.1 0.034 14.1 0.1 1.2 1 0 0 1 1 1 0 Protocadherin PAP_PilO PF06864.12 CDJ88085.1 - 0.03 13.1 0.2 0.043 12.6 0.2 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) DUF2771 PF10969.8 CDJ88085.1 - 0.062 13.3 0.2 0.18 11.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2771) Peptidase_S49_N PF08496.10 CDJ88085.1 - 0.21 11.7 0.1 0.32 11.0 0.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal THF_DHG_CYH PF00763.23 CDJ88086.1 - 0.03 14.6 0.1 0.058 13.7 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain fn3_PAP PF17808.1 CDJ88086.1 - 0.22 11.6 2.6 3.3 7.8 0.1 2.2 2 0 0 2 2 2 0 Fn3-like domain from Purple Acid Phosphatase CDC27 PF09507.10 CDJ88086.1 - 4.4 6.6 12.5 5.9 6.2 12.5 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MSP1_C PF07462.11 CDJ88086.1 - 5.6 5.5 10.1 5.1 5.7 9.2 1.4 1 1 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Hamartin PF04388.12 CDJ88086.1 - 6.2 5.3 12.9 6.4 5.3 12.9 1.0 1 0 0 1 1 1 0 Hamartin protein Tmemb_161AB PF10268.9 CDJ88087.1 - 2.2e-98 330.0 21.3 6.1e-98 328.5 21.3 1.8 1 1 0 1 1 1 1 Predicted transmembrane protein 161AB Sec7 PF01369.20 CDJ88087.1 - 1.4e-69 233.4 0.3 6.1e-69 231.4 0.0 2.3 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.7 CDJ88087.1 - 3.5e-39 134.2 7.3 3.5e-39 134.2 7.3 4.1 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 CDJ88087.1 - 1e-29 103.5 0.7 1e-29 103.5 0.7 2.0 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 CDJ88087.1 - 1e-28 99.0 2.4 2e-26 91.7 0.0 4.5 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) WD40 PF00400.32 CDJ88088.1 - 2.8e-07 31.1 3.4 0.00057 20.6 0.1 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat VPS28 PF03997.12 CDJ88089.1 - 9.8e-59 198.2 0.3 1.1e-58 198.0 0.3 1.0 1 0 0 1 1 1 1 VPS28 protein Nrap_D6 PF17407.2 CDJ88089.1 - 0.12 12.6 0.1 4.9 7.4 0.1 2.3 1 1 0 1 1 1 0 Nrap protein domain 6 CBFD_NFYB_HMF PF00808.23 CDJ88090.1 - 2.4e-19 69.4 0.5 4.5e-19 68.5 0.5 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDJ88090.1 - 9.4e-15 55.1 0.3 1.3e-14 54.7 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 CDJ88090.1 - 0.00065 19.7 0.3 0.0013 18.8 0.3 1.5 1 0 0 1 1 1 1 hTAFII28-like protein conserved region TAF PF02969.17 CDJ88090.1 - 0.0099 16.0 0.1 0.021 15.0 0.1 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-X PF09415.10 CDJ88090.1 - 0.076 13.3 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X RNA_pol_I_A49 PF06870.12 CDJ88091.1 - 1.1e-39 136.5 0.0 1.5e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Treslin_N PF15292.6 CDJ88092.1 - 9.9e-18 63.9 0.1 1.7e-17 63.1 0.1 1.3 1 0 0 1 1 1 1 Treslin N-terminus WDCP PF15390.6 CDJ88092.1 - 3.1 6.1 11.2 0.28 9.5 1.7 2.2 1 1 1 2 2 2 0 WD repeat and coiled-coil-containing protein family Phosphodiest PF01663.22 CDJ88094.1 - 1.7e-12 47.6 1.7 2.5e-11 43.8 0.2 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CDJ88094.1 - 0.00022 20.7 0.7 0.00035 20.0 0.7 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Amino_oxidase PF01593.24 CDJ88095.1 - 4.3e-42 145.0 0.1 3.3e-41 142.1 0.1 2.2 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ88095.1 - 2.5e-11 43.7 0.1 6.8e-11 42.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CDJ88095.1 - 2.4e-07 30.2 0.1 4.9e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 CDJ88095.1 - 3.7e-07 30.1 4.0 3e-06 27.1 3.5 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CDJ88095.1 - 6.9e-06 25.5 0.6 0.0028 16.9 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CDJ88095.1 - 2.9e-05 23.6 0.0 5.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CDJ88095.1 - 3.6e-05 23.1 0.1 0.0039 16.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ88095.1 - 0.00018 20.3 2.0 0.0088 14.8 0.3 2.4 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.12 CDJ88095.1 - 0.00025 20.2 0.7 0.0012 17.9 0.2 2.2 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 CDJ88095.1 - 0.0003 20.8 0.2 0.14 12.1 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 CDJ88095.1 - 0.00035 19.8 1.5 0.00071 18.8 1.5 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 CDJ88095.1 - 0.00062 19.1 1.3 0.0011 18.3 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 CDJ88095.1 - 0.01 16.4 1.7 0.091 13.3 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CDJ88095.1 - 0.01 14.9 0.9 0.17 10.9 0.2 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 CDJ88095.1 - 0.05 12.9 0.0 0.12 11.6 0.0 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SapB_2 PF03489.17 CDJ88096.1 - 0.055 13.6 0.5 0.055 13.6 0.5 2.0 2 0 0 2 2 2 0 Saposin-like type B, region 2 Virul_fac_BrkB PF03631.15 CDJ88096.1 - 0.1 12.2 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Virulence factor BrkB Nterm_IS4 PF13006.7 CDJ88097.1 - 0.12 12.5 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Insertion element 4 transposase N-terminal TGF_beta_GS PF08515.12 CDJ88097.1 - 0.23 11.0 0.2 0.23 11.0 0.2 3.0 3 0 0 3 3 3 0 Transforming growth factor beta type I GS-motif NB-ARC PF00931.22 CDJ88098.1 - 1.6e-06 27.5 0.1 2.7e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain IPP-2 PF04979.14 CDJ88098.1 - 2.3e-05 25.1 1.7 6e-05 23.8 0.3 2.1 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) DUF1758 PF05585.12 CDJ88098.1 - 0.013 15.3 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) YabA PF06156.13 CDJ88098.1 - 0.072 13.7 0.7 4.6 7.9 0.2 2.5 2 0 0 2 2 2 0 Initiation control protein YabA TRPM_tetra PF16519.5 CDJ88098.1 - 0.077 13.1 0.9 0.18 11.9 0.9 1.6 1 0 0 1 1 1 0 Tetramerisation domain of TRPM BLOC1_2 PF10046.9 CDJ88098.1 - 0.092 13.1 0.7 2 8.8 0.3 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 XhlA PF10779.9 CDJ88098.1 - 0.17 12.1 2.3 0.42 10.8 1.0 2.3 2 0 0 2 2 2 0 Haemolysin XhlA HLH PF00010.26 CDJ88099.1 - 4.6e-20 71.3 2.0 4.6e-20 71.3 2.0 1.5 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PilO PF04350.13 CDJ88099.1 - 0.014 15.5 0.3 1.8 8.7 0.1 2.0 1 1 1 2 2 2 0 Pilus assembly protein, PilO DUF3314 PF11771.8 CDJ88099.1 - 0.094 12.8 0.2 0.12 12.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3314) Aldo_ket_red PF00248.21 CDJ88100.1 - 1.2e-46 159.2 0.0 1.5e-45 155.7 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family ssDBP_DBD PF18361.1 CDJ88100.1 - 0.0092 16.1 0.0 0.07 13.2 0.0 2.2 2 1 1 3 3 3 1 Single stranded DNA-binding protein ss DNA binding domain Thioredoxin PF00085.20 CDJ88101.1 - 2.2e-11 43.7 0.0 5.9e-11 42.3 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin DUF953 PF06110.11 CDJ88101.1 - 0.021 14.5 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) AhpC-TSA PF00578.21 CDJ88101.1 - 0.043 13.7 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family CCDC50_N PF15295.6 CDJ88101.1 - 0.052 13.7 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus Thioredoxin_8 PF13905.6 CDJ88101.1 - 0.14 12.5 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like DNA_pol_phi PF04931.13 CDJ88102.1 - 5.5e-36 124.0 27.9 6.6e-24 84.1 15.1 3.5 2 1 1 4 4 4 3 DNA polymerase phi Peptidase_C65 PF10275.9 CDJ88102.1 - 0.097 12.1 0.1 0.6 9.5 0.0 2.2 1 1 1 2 2 2 0 Peptidase C65 Otubain SDA1 PF05285.12 CDJ88102.1 - 0.32 10.4 8.8 0.52 9.7 8.8 1.2 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 CDJ88102.1 - 3.4 6.1 16.2 5.6 5.4 16.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DOMON PF03351.17 CDJ88103.1 - 1.1e-10 41.8 0.0 2.3e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 CDJ88103.1 - 4e-08 33.5 5.6 9.6e-08 32.3 5.6 1.7 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Mem_trans PF03547.18 CDJ88103.1 - 0.00019 19.9 0.2 0.00073 18.0 0.2 1.9 2 0 0 2 2 2 1 Membrane transport protein DUF998 PF06197.13 CDJ88103.1 - 0.64 9.6 13.1 0.66 9.5 5.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF998) Trypan_PARP PF05887.11 CDJ88104.1 - 0.00068 19.6 37.3 0.032 14.2 19.0 2.1 1 1 1 2 2 2 2 Procyclic acidic repetitive protein (PARP) Trypan_PARP PF05887.11 CDJ88105.1 - 1.2e-05 25.2 107.7 1 9.3 14.0 5.0 1 1 2 3 3 3 1 Procyclic acidic repetitive protein (PARP) CEP63 PF17045.5 CDJ88106.1 - 0.033 14.1 0.1 0.041 13.8 0.1 1.1 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Rad1 PF02144.16 CDJ88107.1 - 1e-58 198.6 1.0 1.7e-58 197.8 1.0 1.4 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 PCNA_C PF02747.15 CDJ88107.1 - 1.5e-06 28.4 0.4 3.2e-06 27.3 0.2 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 CDJ88107.1 - 0.00024 20.6 0.2 0.031 13.7 0.2 2.4 1 1 0 1 1 1 1 Rad9 Chrome_Resist PF09828.9 CDJ88107.1 - 0.09 13.2 0.1 3.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Chromate resistance exported protein PH PF00169.29 CDJ88108.1 - 2.5e-10 40.8 0.3 5.2e-10 39.8 0.3 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CDJ88108.1 - 0.037 14.5 0.4 0.079 13.4 0.4 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain CAP PF00188.26 CDJ88109.1 - 2.6e-12 47.7 0.3 3.6e-12 47.2 0.3 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SPATA3 PF15662.5 CDJ88109.1 - 0.12 13.0 1.0 0.24 12.0 1.0 1.5 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family SAPS PF04499.15 CDJ88110.1 - 0.015 14.1 0.0 0.017 13.9 0.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4037 PF13228.6 CDJ88110.1 - 0.065 14.0 0.1 0.1 13.4 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4037) BACK PF07707.15 CDJ88110.1 - 0.086 13.0 0.0 0.61 10.2 0.0 1.9 1 1 1 2 2 2 0 BTB And C-terminal Kelch Mtp PF03821.16 CDJ88111.1 - 0.016 14.8 4.5 0.043 13.4 1.0 2.3 1 1 1 2 2 2 0 Golgi 4-transmembrane spanning transporter Acyl_transf_3 PF01757.22 CDJ88111.1 - 0.021 13.9 7.1 0.027 13.5 7.1 1.1 1 0 0 1 1 1 0 Acyltransferase family SLAC1 PF03595.17 CDJ88111.1 - 0.039 13.2 8.6 0.57 9.4 2.5 2.0 1 1 1 2 2 2 0 Voltage-dependent anion channel PHO4 PF01384.20 CDJ88111.1 - 0.19 10.7 3.8 0.26 10.3 3.8 1.3 1 0 0 1 1 1 0 Phosphate transporter family COX7a PF02238.15 CDJ88111.1 - 0.32 11.4 2.9 9.2 6.8 0.4 3.0 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VII TcpE PF12648.7 CDJ88111.1 - 5.2 7.7 9.4 0.99 10.0 2.9 2.4 1 1 1 2 2 2 0 TcpE family Cpn60_TCP1 PF00118.24 CDJ88112.1 - 9.6e-158 525.8 2.2 1.3e-157 525.4 2.2 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RVT_1 PF00078.27 CDJ88113.1 - 5.3e-07 29.4 0.0 7.8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Helitron_like_N PF14214.6 CDJ88114.1 - 4.8e-61 206.3 0.0 1.1e-60 205.2 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 CDJ88114.1 - 9.7e-32 110.5 0.0 1.4e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CDJ88114.1 - 6.5e-07 29.2 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ88114.1 - 0.0015 18.9 0.0 0.004 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CDJ88114.1 - 0.016 15.2 0.0 0.055 13.5 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NB-ARC PF00931.22 CDJ88114.1 - 0.022 14.0 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 CDJ88114.1 - 0.031 14.7 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 CDJ88114.1 - 0.039 13.0 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AFG1_ATPase PF03969.16 CDJ88114.1 - 0.042 12.7 0.0 0.54 9.1 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase AAA_22 PF13401.6 CDJ88114.1 - 0.074 13.3 0.0 0.23 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain CAP PF00188.26 CDJ88115.1 - 1.2e-08 35.8 0.2 1.8e-08 35.3 0.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ88115.1 - 0.00028 21.1 1.0 0.00061 20.1 1.0 1.6 1 1 0 1 1 1 1 Ancylostoma-associated secreted protein related DUF2846 PF11008.8 CDJ88115.1 - 0.043 13.8 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) CAP PF00188.26 CDJ88116.1 - 6e-08 33.6 0.1 1e-07 32.8 0.1 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ88116.1 - 0.00067 19.9 1.1 0.0013 19.0 1.1 1.6 1 1 0 1 1 1 1 Ancylostoma-associated secreted protein related CAP PF00188.26 CDJ88117.1 - 8.6e-10 39.5 0.1 1.2e-09 39.1 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ88117.1 - 0.0015 18.8 0.2 0.0049 17.1 0.2 1.8 1 1 0 1 1 1 1 Ancylostoma-associated secreted protein related Vfa1 PF08432.10 CDJ88118.1 - 4.9 7.5 19.7 6 7.2 19.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NPR3 PF03666.13 CDJ88118.1 - 5.2 5.8 14.1 5.2 5.7 14.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Methyltransf_3 PF01596.17 CDJ88119.1 - 1.6e-39 135.3 0.0 1.8e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 CDJ88119.1 - 1.5e-07 32.4 0.0 2.4e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ88119.1 - 0.0034 17.2 0.0 0.0071 16.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Thioredoxin PF00085.20 CDJ88120.1 - 9.2e-63 208.7 0.1 1.2e-21 76.7 0.0 5.6 6 0 0 6 6 6 4 Thioredoxin DnaJ PF00226.31 CDJ88120.1 - 3.8e-23 81.4 5.4 7.3e-23 80.5 5.4 1.5 1 0 0 1 1 1 1 DnaJ domain OST3_OST6 PF04756.13 CDJ88120.1 - 6.2e-08 32.3 0.1 0.033 13.5 0.0 4.2 4 1 0 4 4 4 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CDJ88120.1 - 1.2e-07 32.0 1.5 0.81 10.1 0.0 5.7 5 2 1 6 6 6 3 Thioredoxin-like Thioredoxin_2 PF13098.6 CDJ88120.1 - 3.5e-06 27.4 5.3 1.5 9.3 0.1 5.2 4 3 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CDJ88120.1 - 0.0053 16.9 0.5 2.3 8.5 0.0 3.3 3 0 0 3 3 3 1 Thioredoxin-like TraF PF13728.6 CDJ88120.1 - 0.013 15.3 0.1 0.37 10.6 0.0 2.6 3 0 0 3 3 3 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 CDJ88120.1 - 0.032 14.0 2.5 0.13 12.1 0.1 2.9 3 0 0 3 3 3 0 Thioredoxin HlyC PF02794.16 CDJ88120.1 - 0.083 12.8 0.3 2.4 8.1 0.0 3.0 3 0 0 3 3 3 0 RTX toxin acyltransferase family DUF2499 PF10693.9 CDJ88120.1 - 0.09 13.1 0.0 16 5.8 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2499) Keratin_2_head PF16208.5 CDJ88121.1 - 5.7 7.1 18.4 6.8 6.8 18.4 1.1 1 0 0 1 1 1 0 Keratin type II head tRNA-synt_2b PF00587.25 CDJ88122.1 - 2.7e-25 89.4 0.0 5.8e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CDJ88122.1 - 0.0016 18.6 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain LSM PF01423.22 CDJ88123.1 - 1.1e-06 28.2 0.0 1.2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain Cyclin_N PF00134.23 CDJ88124.1 - 1.5e-38 131.4 3.4 9.7e-37 125.6 0.3 2.3 1 1 1 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 CDJ88124.1 - 4.1e-17 62.4 1.1 4.1e-17 62.4 1.1 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain Rpn9_C PF18261.1 CDJ88124.1 - 0.7 9.5 0.0 0.7 9.5 0.0 2.4 3 0 0 3 3 3 0 Rpn9 C-terminal helix AMP-binding PF00501.28 CDJ88125.1 - 3.5e-59 200.5 0.0 4.7e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ88125.1 - 4.4e-06 27.6 0.0 9.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 CDJ88126.1 - 1.3e-52 178.7 0.0 2.6e-35 122.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain PH_3 PF14593.6 CDJ88126.1 - 9.3e-41 138.2 0.0 2.3e-40 136.9 0.0 1.7 1 0 0 1 1 1 1 PH domain Pkinase_Tyr PF07714.17 CDJ88126.1 - 2.4e-21 76.2 0.0 2.2e-16 59.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDJ88126.1 - 2.8e-05 23.6 0.1 0.026 13.8 0.0 2.7 3 0 0 3 3 3 2 Kinase-like PH_8 PF15409.6 CDJ88126.1 - 0.0028 17.9 0.0 0.0056 16.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 CDJ88126.1 - 0.0032 18.0 0.0 0.0085 16.6 0.0 1.7 1 0 0 1 1 1 1 PH domain Haspin_kinase PF12330.8 CDJ88126.1 - 0.024 13.6 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 CDJ88126.1 - 0.027 13.3 0.0 0.049 12.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CDJ88126.1 - 0.028 13.8 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDJ88126.1 - 0.19 11.3 0.2 0.46 10.0 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Myotub-related PF06602.14 CDJ88127.1 - 4.4e-50 170.6 0.3 5e-41 140.8 0.1 2.2 1 1 1 2 2 2 2 Myotubularin-like phosphatase domain 3-PAP PF12578.8 CDJ88127.1 - 5e-08 32.8 0.0 1.3e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Myotubularin-associated protein Pkinase_Tyr PF07714.17 CDJ88128.1 - 2.1e-85 286.1 0.0 2.6e-85 285.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ88128.1 - 4e-46 157.5 0.0 5.4e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDJ88128.1 - 9e-22 77.0 0.2 1.9e-21 75.9 0.2 1.6 1 0 0 1 1 1 1 SH2 domain Kinase-like PF14531.6 CDJ88128.1 - 0.00013 21.4 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CDJ88128.1 - 0.0027 17.7 0.0 0.0054 16.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ88128.1 - 0.046 12.5 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PA26 PF04636.13 CDJ88129.1 - 8.7e-88 295.2 1.2 5.3e-87 292.6 1.2 1.8 1 1 0 1 1 1 1 PA26 p53-induced protein (sestrin) CMD PF02627.20 CDJ88129.1 - 0.017 15.2 0.0 0.17 12.0 0.0 2.2 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family Exo_endo_phos PF03372.23 CDJ88130.1 - 7.3e-12 45.3 0.5 1.2e-11 44.6 0.5 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CDJ88130.1 - 0.0084 16.0 1.2 0.046 13.6 1.2 2.3 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Sel_put PF04328.13 CDJ88130.1 - 0.075 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Selenoprotein, putative RAC_head PF16717.5 CDJ88131.1 - 0.0068 17.4 0.3 0.017 16.1 0.1 1.7 2 0 0 2 2 2 1 Ribosome-associated complex head domain Plug_translocon PF10559.9 CDJ88131.1 - 0.01 15.7 0.1 0.028 14.3 0.1 1.8 1 0 0 1 1 1 0 Plug domain of Sec61p 7TM_GPCR_Srsx PF10320.9 CDJ88132.1 - 1.3e-09 37.9 8.3 1.7e-09 37.5 8.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx YpmT PF17431.2 CDJ88132.1 - 0.014 15.4 2.9 0.014 15.4 0.8 2.1 1 1 1 2 2 2 0 Uncharacterized YmpT-like 7TM_GPCR_Srsx PF10320.9 CDJ88133.1 - 3.5e-14 52.8 4.6 4.4e-14 52.5 4.6 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 CDJ88133.1 - 1.8e-11 43.9 4.4 2.1e-11 43.6 4.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CDJ88133.1 - 0.0025 17.5 7.0 0.0027 17.4 7.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx LON_substr_bdg PF02190.16 CDJ88134.1 - 9.9e-11 41.9 0.0 1.7e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Yippee-Mis18 PF03226.14 CDJ88134.1 - 2.4e-05 24.5 0.1 4.9e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2379 PF09543.10 CDJ88134.1 - 0.068 13.4 0.2 0.13 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) RRM_1 PF00076.22 CDJ88135.1 - 6e-25 86.9 0.4 9e-13 47.9 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ88135.1 - 9.7e-11 41.4 0.0 1.7e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 CDJ88135.1 - 2.9e-06 26.9 0.0 0.0052 16.4 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 CDJ88135.1 - 0.00076 19.3 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) DUF1027 PF06265.11 CDJ88135.1 - 0.014 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) DUF3887 PF13026.6 CDJ88135.1 - 0.087 13.7 0.0 0.2 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3887) PHM7_cyt PF14703.6 CDJ88135.1 - 0.13 12.4 0.5 5.6 7.2 0.0 2.7 2 2 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter HSCB_C PF07743.13 CDJ88136.1 - 3.7e-15 56.2 1.3 2.1e-13 50.6 0.2 2.3 2 0 0 2 2 2 2 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 CDJ88136.1 - 1.6e-07 31.3 0.4 2.8e-07 30.5 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain HscB_4_cys PF18256.1 CDJ88136.1 - 0.028 14.2 6.0 0.074 12.9 6.0 1.7 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif Transketolase_N PF00456.21 CDJ88137.1 - 6.9e-48 163.3 0.1 1.2e-47 162.5 0.1 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CDJ88137.1 - 1.3e-37 129.1 0.0 2.5e-37 128.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CDJ88137.1 - 7.4e-33 113.1 0.1 1.4e-32 112.2 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 CDJ88137.1 - 2e-12 46.7 0.2 3.2e-12 46.0 0.2 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CDJ88137.1 - 7.1e-06 25.4 0.1 0.013 14.7 0.1 2.6 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.10 CDJ88137.1 - 0.00093 18.1 0.1 0.0015 17.4 0.1 1.3 1 0 0 1 1 1 1 XFP N-terminal domain CHASE2 PF05226.11 CDJ88137.1 - 0.0012 18.6 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 CHASE2 domain TPP_enzyme_C PF02775.21 CDJ88137.1 - 0.0021 17.8 0.3 0.015 15.1 0.3 2.4 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DHDPS PF00701.22 CDJ88137.1 - 0.0067 15.2 0.0 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Aldedh PF00171.22 CDJ88138.1 - 3.5e-171 569.8 0.0 4.8e-171 569.3 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Formyl_trans_N PF00551.19 CDJ88138.1 - 6.4e-41 140.1 0.0 1.2e-40 139.2 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 CDJ88138.1 - 6.8e-11 42.3 0.0 1.8e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain PP-binding PF00550.25 CDJ88138.1 - 7e-05 23.1 0.0 0.00017 21.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF1487 PF07368.11 CDJ88138.1 - 0.046 13.2 0.0 0.17 11.3 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Hydrolase_4 PF12146.8 CDJ88139.1 - 9.3e-10 38.2 0.0 0.00066 19.0 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ88139.1 - 5.8e-06 26.1 0.0 0.03 13.9 0.0 2.9 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 CDJ88139.1 - 0.0053 16.6 0.0 2.9 7.6 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.13 CDJ88139.1 - 0.0072 16.2 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase LIP PF03583.14 CDJ88139.1 - 0.0083 15.5 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 CDJ88139.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family FSH1 PF03959.13 CDJ88139.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.18 CDJ88139.1 - 0.19 11.3 0.0 0.46 10.0 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family MFS_1 PF07690.16 CDJ88140.1 - 7.5e-39 133.6 44.4 3.4e-36 124.9 30.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CDJ88140.1 - 0.043 12.1 0.0 0.043 12.1 0.0 2.8 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family EphA2_TM PF14575.6 CDJ88141.1 - 0.059 14.2 0.3 1.3 9.9 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain MSC PF09402.10 CDJ88141.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Shisa PF13908.6 CDJ88141.1 - 0.68 10.2 2.2 2.8 8.2 0.6 1.9 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Orf78 PF06024.12 CDJ88141.1 - 1.6 9.0 4.2 1.2 9.4 2.8 1.6 1 1 0 1 1 1 0 Orf78 (ac78) FH2 PF02181.23 CDJ88142.1 - 1.1e-22 80.6 2.1 1.1e-22 80.6 2.1 1.4 2 0 0 2 2 2 1 Formin Homology 2 Domain zf-H2C2_5 PF13909.6 CDJ88142.1 - 0.018 14.8 0.5 0.043 13.6 0.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain DUF3795 PF12675.7 CDJ88142.1 - 1.4 9.4 7.4 3.1 8.3 7.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) SNF PF00209.18 CDJ88144.1 - 1.4e-27 96.6 40.4 1.5e-25 90.0 40.4 2.2 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF148 PF02520.17 CDJ88146.1 - 5.5e-27 94.0 5.8 6.5e-27 93.8 5.8 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 Metal_resist PF13801.6 CDJ88146.1 - 0.00062 19.9 1.2 0.0076 16.4 0.1 2.9 1 1 2 4 4 4 1 Heavy-metal resistance Baculo_PEP_C PF04513.12 CDJ88146.1 - 0.0019 18.2 1.3 0.0026 17.8 1.3 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Mer2 PF09074.10 CDJ88146.1 - 0.0023 17.8 0.9 0.0029 17.5 0.9 1.1 1 0 0 1 1 1 1 Mer2 DUF1798 PF08807.10 CDJ88146.1 - 0.0065 16.6 1.5 0.01 15.9 1.2 1.5 1 1 0 1 1 1 1 Bacterial domain of unknown function (DUF1798) DUF3585 PF12130.8 CDJ88146.1 - 0.013 15.7 1.2 0.017 15.2 1.2 1.1 1 0 0 1 1 1 0 Bivalent Mical/EHBP Rab binding domain Fib_alpha PF08702.10 CDJ88146.1 - 0.027 14.6 2.4 0.037 14.2 2.4 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF241 PF03087.14 CDJ88146.1 - 0.039 13.8 0.1 0.047 13.5 0.1 1.1 1 0 0 1 1 1 0 Arabidopsis protein of unknown function DUF5304 PF17230.2 CDJ88146.1 - 0.042 14.1 0.5 0.065 13.5 0.4 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5304) DUF1664 PF07889.12 CDJ88146.1 - 0.048 13.7 1.1 0.074 13.1 0.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) ERM PF00769.19 CDJ88146.1 - 0.072 12.9 0.6 0.091 12.6 0.6 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family NB-ARC PF00931.22 CDJ88146.1 - 0.078 12.1 0.1 0.1 11.8 0.1 1.1 1 0 0 1 1 1 0 NB-ARC domain HEPN_AbiA_CTD PF18732.1 CDJ88146.1 - 0.08 12.9 0.2 0.11 12.5 0.2 1.2 1 0 0 1 1 1 0 HEPN like, Abia C-terminal domain DUF16 PF01519.16 CDJ88146.1 - 0.096 13.2 2.2 0.35 11.4 2.2 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF16 FAD-SLDH PF12318.8 CDJ88146.1 - 0.11 12.6 2.1 0.27 11.3 0.3 1.9 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Phage_GP20 PF06810.11 CDJ88146.1 - 0.12 12.2 3.2 0.16 11.7 3.2 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 Phage_GPO PF05929.11 CDJ88146.1 - 0.13 11.8 2.6 0.17 11.5 2.6 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase HrpB2 PF09487.10 CDJ88146.1 - 0.25 11.8 3.2 1.3 9.4 1.5 2.1 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB2) DUF1722 PF08349.11 CDJ88146.1 - 0.25 11.6 1.0 0.81 10.0 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1722) BST2 PF16716.5 CDJ88146.1 - 0.33 11.6 2.9 12 6.6 0.3 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 F_actin_bind PF08919.10 CDJ88146.1 - 0.4 10.8 1.9 8.7 6.5 0.4 2.1 1 1 1 2 2 2 0 F-actin binding Prominin PF05478.11 CDJ88146.1 - 0.46 8.4 2.4 0.83 7.5 1.7 1.4 1 1 1 2 2 2 0 Prominin LPP PF04728.13 CDJ88146.1 - 0.57 10.6 2.8 13 6.2 0.1 2.4 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Mito_fiss_reg PF05308.11 CDJ88146.1 - 1.8 8.6 6.3 0.82 9.7 2.4 1.9 1 1 1 2 2 2 0 Mitochondrial fission regulator TMF_DNA_bd PF12329.8 CDJ88146.1 - 2 8.5 5.3 4 7.5 2.4 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.12 CDJ88146.1 - 2.2 8.8 4.9 2.6 8.6 2.5 2.1 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein PRIMA1 PF16101.5 CDJ88146.1 - 7.4 6.6 6.3 12 6.0 6.3 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF148 PF02520.17 CDJ88147.1 - 5.8e-26 90.7 6.6 8.1e-26 90.3 6.6 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 PIN_8 PF18476.1 CDJ88147.1 - 0.034 14.0 3.5 0.043 13.7 3.5 1.1 1 0 0 1 1 1 0 PIN like domain Resolvase PF00239.21 CDJ88147.1 - 0.035 14.2 0.3 0.069 13.3 0.2 1.5 1 1 0 1 1 1 0 Resolvase, N terminal domain RsbRD_N PF14361.6 CDJ88147.1 - 0.037 14.7 0.8 0.075 13.7 0.8 1.5 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain DUF4268 PF14088.6 CDJ88147.1 - 0.055 13.3 3.7 0.087 12.7 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) KapB PF08810.10 CDJ88147.1 - 0.067 13.4 1.0 0.11 12.6 1.0 1.4 1 0 0 1 1 1 0 Kinase associated protein B THP2 PF09432.10 CDJ88147.1 - 0.075 13.1 4.9 0.19 11.8 1.4 2.3 1 1 1 2 2 2 0 Tho complex subunit THP2 HSCB_C PF07743.13 CDJ88147.1 - 0.1 13.1 1.9 0.24 11.9 1.8 1.7 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain EcoEI_R_C PF08463.10 CDJ88147.1 - 0.11 12.7 3.9 0.98 9.5 0.4 2.1 1 1 1 2 2 2 0 EcoEI R protein C-terminal RuvX PF03652.15 CDJ88147.1 - 0.25 11.7 1.4 0.36 11.2 1.4 1.2 1 0 0 1 1 1 0 Holliday junction resolvase Sigma70_ner PF04546.13 CDJ88147.1 - 0.53 10.1 10.4 0.19 11.6 3.3 2.3 2 1 0 2 2 2 0 Sigma-70, non-essential region DUF148 PF02520.17 CDJ88148.1 - 4.2e-24 84.8 5.9 5.2e-24 84.5 5.9 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 BAG PF02179.16 CDJ88148.1 - 0.12 12.8 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 BAG domain DUF148 PF02520.17 CDJ88149.1 - 1.2e-23 83.3 9.5 1.5e-23 83.0 9.5 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 KapB PF08810.10 CDJ88149.1 - 0.0029 17.7 0.6 0.0045 17.1 0.6 1.3 1 0 0 1 1 1 1 Kinase associated protein B DUF4407 PF14362.6 CDJ88149.1 - 0.0082 15.5 1.6 0.011 15.1 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) SHE3 PF17078.5 CDJ88149.1 - 0.017 14.9 2.8 0.026 14.3 2.8 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF2508 PF10704.9 CDJ88149.1 - 0.018 15.2 2.1 0.033 14.4 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) DUF1664 PF07889.12 CDJ88149.1 - 0.034 14.2 1.0 0.056 13.5 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4404 PF14357.6 CDJ88149.1 - 0.062 13.9 3.9 4.1 8.1 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF2130 PF09903.9 CDJ88149.1 - 0.082 12.2 5.3 0.12 11.6 5.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) Helo_like_N PF17111.5 CDJ88149.1 - 0.09 12.1 3.0 0.13 11.6 3.0 1.1 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Maf1 PF09174.10 CDJ88149.1 - 0.17 12.0 2.4 0.21 11.7 1.7 1.5 2 0 0 2 2 2 0 Maf1 regulator HsdM_N PF12161.8 CDJ88149.1 - 0.33 11.6 3.8 0.45 11.1 2.6 1.7 1 1 1 2 2 2 0 HsdM N-terminal domain OmpH PF03938.14 CDJ88149.1 - 0.36 11.2 6.7 0.63 10.4 6.7 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Metal_resist PF13801.6 CDJ88149.1 - 0.64 10.2 0.1 0.64 10.2 0.1 3.5 2 1 2 4 4 4 0 Heavy-metal resistance TolA_bind_tri PF16331.5 CDJ88149.1 - 1.5 9.0 3.3 1.7 8.8 0.3 2.2 1 1 1 2 2 2 0 TolA binding protein trimerisation BRE1 PF08647.11 CDJ88149.1 - 6.2 7.0 10.0 13 6.0 3.8 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4817 PF16087.5 CDJ88150.1 - 0.25 11.2 0.0 0.4 10.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) PKD PF00801.20 CDJ88151.1 - 6.2e-08 32.4 3.3 0.018 14.9 0.2 4.9 4 0 0 4 4 4 2 PKD domain DUF4625 PF15418.6 CDJ88151.1 - 7.7e-07 29.4 0.0 0.52 10.6 0.0 3.5 3 0 0 3 3 3 3 Domain of unknown function (DUF4625) Big_9 PF17963.1 CDJ88151.1 - 8.4e-05 23.2 13.4 0.29 11.9 0.6 4.9 5 0 0 5 5 5 3 Bacterial Ig domain EGF_2 PF07974.13 CDJ88151.1 - 0.00091 19.5 6.7 0.00091 19.5 6.7 2.5 2 0 0 2 2 2 1 EGF-like domain Y_Y_Y PF07495.13 CDJ88151.1 - 0.011 15.6 0.0 3.4 7.7 0.0 3.5 4 0 0 4 4 4 0 Y_Y_Y domain He_PIG PF05345.12 CDJ88151.1 - 0.014 15.6 2.5 12 6.2 0.0 4.6 4 0 0 4 4 4 0 Putative Ig domain Cadherin PF00028.17 CDJ88151.1 - 0.04 14.4 0.5 25 5.4 0.0 3.5 4 0 0 4 4 4 0 Cadherin domain EGF_Tenascin PF18720.1 CDJ88151.1 - 0.041 13.9 1.0 0.12 12.4 1.0 1.8 1 0 0 1 1 1 0 Tenascin EGF domain DUF5013 PF16405.5 CDJ88151.1 - 0.1 12.8 1.3 61 3.9 0.0 4.5 4 1 2 6 6 6 0 Domain of unknown function (DUF5013) bZIP_1 PF00170.21 CDJ88151.1 - 2.4 8.3 6.6 6.8 6.9 6.6 1.7 1 0 0 1 1 1 0 bZIP transcription factor ASXH PF13919.6 CDJ88152.1 - 0.0013 18.7 0.0 0.0037 17.3 0.0 1.7 1 0 0 1 1 1 1 Asx homology domain TTR-52 PF01060.23 CDJ88153.1 - 5e-30 104.0 0.0 7e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 Transthyretin-like family Transthyretin PF00576.21 CDJ88153.1 - 0.063 14.0 0.0 0.085 13.5 0.0 1.2 1 0 0 1 1 1 0 HIUase/Transthyretin family DUF4198 PF10670.9 CDJ88153.1 - 0.07 13.5 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) Phage_BR0599 PF09356.10 CDJ88153.1 - 0.12 12.8 0.0 0.16 12.3 0.0 1.4 1 1 0 1 1 1 0 Phage conserved hypothetical protein BR0599 TTR-52 PF01060.23 CDJ88154.1 - 8.8e-28 96.8 0.0 1.6e-27 96.0 0.0 1.4 2 0 0 2 2 2 1 Transthyretin-like family DUF4198 PF10670.9 CDJ88154.1 - 0.0015 18.9 0.0 0.0027 18.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4198) bMG3 PF11974.8 CDJ88154.1 - 0.0017 18.4 0.0 0.022 14.8 0.0 2.1 1 1 0 1 1 1 1 Bacterial alpha-2-macroglobulin MG3 domain CarboxypepD_reg PF13620.6 CDJ88154.1 - 0.0069 16.6 0.1 0.012 15.9 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain MetallophosN PF16371.5 CDJ88154.1 - 0.0091 16.2 0.8 0.58 10.5 0.1 2.7 2 1 1 3 3 3 1 N terminal of Calcineurin-like phosphoesterase Transthyretin PF00576.21 CDJ88154.1 - 0.024 15.3 0.0 0.037 14.7 0.0 1.3 1 0 0 1 1 1 0 HIUase/Transthyretin family SpaA PF17802.1 CDJ88154.1 - 0.082 13.2 0.0 0.12 12.7 0.0 1.5 1 1 0 1 1 1 0 Prealbumin-like fold domain BRICHOS PF04089.14 CDJ88155.1 - 0.00012 22.2 0.3 0.00062 20.0 0.0 2.4 3 0 0 3 3 3 1 BRICHOS domain COesterase PF00135.28 CDJ88156.1 - 7.5e-31 107.6 0.0 8e-31 107.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family HTH_48 PF17906.1 CDJ88157.1 - 2.1e-19 69.4 0.9 3.6e-19 68.6 0.9 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_Tnp_IS630 PF01710.16 CDJ88157.1 - 1.5e-06 28.2 0.0 1.8e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 CDJ88157.1 - 2.9e-05 23.7 0.0 0.16 11.8 0.0 2.4 2 0 0 2 2 2 2 Homeodomain-like domain HTH_38 PF13936.6 CDJ88157.1 - 3.1e-05 23.7 0.0 6.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 CDJ88157.1 - 0.00011 22.3 0.1 0.00067 19.9 0.1 1.9 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 CDJ88157.1 - 0.00059 20.4 0.0 0.00086 19.9 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 CDJ88157.1 - 0.0023 18.0 0.0 1.5 9.0 0.0 2.6 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_11 PF08279.12 CDJ88157.1 - 0.0053 16.7 0.0 0.009 15.9 0.0 1.4 1 0 0 1 1 1 1 HTH domain HTH_50 PF18024.1 CDJ88157.1 - 0.021 14.4 0.5 0.038 13.6 0.0 1.6 2 0 0 2 2 1 0 Helix-turn-helix domain Terminase_5 PF06056.12 CDJ88157.1 - 0.039 13.8 0.0 6.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) IF2_N PF04760.15 CDJ88157.1 - 0.04 13.7 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region TnsD PF15978.5 CDJ88157.1 - 0.05 12.6 0.0 0.05 12.6 0.0 1.2 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_5 PF01022.20 CDJ88157.1 - 0.054 13.4 0.1 0.09 12.7 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_29 PF13551.6 CDJ88157.1 - 0.088 12.8 0.0 1.9 8.5 0.0 2.2 1 1 1 2 2 2 0 Winged helix-turn helix HTH_36 PF13730.6 CDJ88157.1 - 0.09 12.7 0.0 0.62 10.1 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_6 PF01418.17 CDJ88157.1 - 0.17 11.9 0.0 0.61 10.1 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family DUF4817 PF16087.5 CDJ88157.1 - 0.28 11.0 2.1 0.25 11.2 0.3 1.9 2 1 0 2 2 2 0 Helix-turn-helix domain (DUF4817) COesterase PF00135.28 CDJ88158.1 - 3.4e-136 455.1 0.0 4.1e-136 454.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDJ88158.1 - 4.7e-07 29.9 0.8 1.4e-06 28.3 0.8 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CDJ88158.1 - 0.016 14.1 0.1 2.5 6.9 0.0 2.1 2 0 0 2 2 2 0 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 CDJ88158.1 - 0.075 13.6 0.3 0.16 12.6 0.3 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family HTH_48 PF17906.1 CDJ88159.1 - 1.7e-18 66.5 0.8 2.7e-18 65.8 0.8 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_Tnp_IS630 PF01710.16 CDJ88159.1 - 1.8e-05 24.7 0.0 2.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 CDJ88159.1 - 0.00046 19.9 0.1 1.4 8.9 0.0 2.5 2 0 0 2 2 2 2 Homeodomain-like domain HTH_32 PF13565.6 CDJ88159.1 - 0.00053 20.5 0.1 0.0022 18.6 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.6 CDJ88159.1 - 0.001 18.8 0.2 0.0066 16.2 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_6 PF01418.17 CDJ88159.1 - 0.012 15.6 0.2 0.034 14.1 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family Transposase_1 PF01359.18 CDJ88159.1 - 0.015 15.1 0.9 0.027 14.3 0.1 1.8 2 0 0 2 2 2 0 Transposase (partial DDE domain) HTH_28 PF13518.6 CDJ88159.1 - 0.032 14.4 0.0 8.3 6.6 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 CDJ88159.1 - 0.038 14.2 0.2 0.16 12.2 0.1 2.0 2 0 0 2 2 2 0 Transposase HTH_11 PF08279.12 CDJ88159.1 - 0.061 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 HTH domain Rhomboid PF01694.22 CDJ88162.1 - 4.7e-31 107.8 12.2 4.7e-31 107.8 12.2 2.0 1 1 1 2 2 2 1 Rhomboid family AA_permease_2 PF13520.6 CDJ88162.1 - 0.0099 14.8 8.4 0.012 14.5 8.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3087 PF11286.8 CDJ88162.1 - 0.34 10.4 3.9 0.16 11.4 0.2 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3087) DUF1275 PF06912.11 CDJ88162.1 - 0.48 10.3 13.8 0.64 9.9 5.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1275) DUF1129 PF06570.11 CDJ88162.1 - 0.98 8.9 4.1 1.6 8.2 3.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) DUF5083 PF16890.5 CDJ88162.1 - 1.2 8.8 5.8 1.5 8.6 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5083) DUF2304 PF10066.9 CDJ88162.1 - 1.6 9.0 11.4 0.27 11.5 6.0 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2304) MNHE PF01899.16 CDJ88162.1 - 2.5 7.8 11.2 0.054 13.2 1.9 2.3 2 1 0 2 2 2 0 Na+/H+ ion antiporter subunit MtrE PF04206.12 CDJ88162.1 - 4.2 6.6 9.8 0.55 9.5 3.3 2.2 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit E DUF4203 PF13886.6 CDJ88162.1 - 5.4 6.6 19.9 0.67 9.6 5.2 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4203) PHO4 PF01384.20 CDJ88162.1 - 7.7 5.5 7.0 9.6 5.1 7.0 1.2 1 0 0 1 1 1 0 Phosphate transporter family TUDOR PF00567.24 CDJ88163.1 - 1.8e-09 37.7 0.0 3.3e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Tudor domain G-gamma PF00631.22 CDJ88164.1 - 3e-12 46.4 0.0 3.3e-12 46.2 0.0 1.0 1 0 0 1 1 1 1 GGL domain AAA PF00004.29 CDJ88165.1 - 1.4e-17 64.3 0.0 2.4e-17 63.6 0.0 1.4 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CDJ88165.1 - 1.6e-12 47.5 0.0 3.4e-09 36.7 0.0 2.1 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA_24 PF13479.6 CDJ88165.1 - 2.6e-06 27.3 0.0 3.7e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ88165.1 - 6e-06 26.8 0.0 2.7e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 CDJ88165.1 - 1e-05 25.6 0.0 6.5e-05 22.9 0.0 1.8 1 1 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 CDJ88165.1 - 3.7e-05 24.0 0.0 0.023 14.9 0.0 2.2 1 1 1 2 2 2 2 AAA domain TniB PF05621.11 CDJ88165.1 - 0.00015 21.3 0.0 0.0035 16.8 0.0 2.1 1 1 1 2 2 2 1 Bacterial TniB protein AAA_11 PF13086.6 CDJ88165.1 - 0.00021 21.2 0.0 0.00071 19.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CDJ88165.1 - 0.00029 20.6 0.0 0.00051 19.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 CDJ88165.1 - 0.00033 19.9 0.0 0.00044 19.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 CDJ88165.1 - 0.00043 20.3 0.0 0.001 19.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DEAD PF00270.29 CDJ88165.1 - 0.00054 19.8 0.0 0.38 10.5 0.0 2.1 1 1 1 2 2 2 2 DEAD/DEAH box helicase IstB_IS21 PF01695.17 CDJ88165.1 - 0.00098 18.9 0.0 0.0021 17.8 0.0 1.5 1 1 0 1 1 1 1 IstB-like ATP binding protein ResIII PF04851.15 CDJ88165.1 - 0.0021 18.1 0.0 0.026 14.5 0.0 2.0 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 CDJ88165.1 - 0.0029 17.0 0.0 0.015 14.6 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CDJ88165.1 - 0.0035 17.2 0.0 0.0057 16.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CDJ88165.1 - 0.005 16.4 0.0 0.014 15.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CDJ88165.1 - 0.0055 16.7 0.0 0.0083 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CDJ88165.1 - 0.011 15.8 0.0 0.07 13.2 0.0 1.9 1 1 1 2 2 2 0 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 CDJ88165.1 - 0.012 14.9 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 CDJ88165.1 - 0.014 15.7 0.0 0.051 14.0 0.0 1.8 2 0 0 2 2 2 0 RNA helicase PhoH PF02562.16 CDJ88165.1 - 0.029 13.8 0.0 0.62 9.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.9 CDJ88165.1 - 0.03 13.6 0.0 0.75 9.0 0.0 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Kinesin PF00225.23 CDJ88165.1 - 0.033 13.1 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain AAA_30 PF13604.6 CDJ88165.1 - 0.034 13.9 0.1 0.082 12.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CDJ88165.1 - 0.047 14.3 0.0 0.065 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CDJ88165.1 - 0.047 14.0 0.0 0.12 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 CDJ88165.1 - 0.06 13.5 0.0 0.09 12.9 0.0 1.4 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.6 CDJ88165.1 - 0.07 13.3 0.0 0.13 12.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 CDJ88165.1 - 0.074 12.1 0.0 0.18 10.8 0.0 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 CDJ88165.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 CDJ88165.1 - 0.14 11.9 0.0 1.2 8.8 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain Zip PF02535.22 CDJ88166.1 - 3.8e-29 102.0 6.9 4.2e-29 101.8 6.9 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter ubiquitin PF00240.23 CDJ88167.1 - 6.3e-270 871.7 43.2 5.1e-33 112.6 0.4 8.0 8 0 0 8 8 8 8 Ubiquitin family Rad60-SLD PF11976.8 CDJ88167.1 - 2.1e-125 408.7 46.7 5e-15 55.1 0.5 8.0 8 0 0 8 8 8 8 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDJ88167.1 - 1.2e-44 150.7 21.8 0.00093 19.6 0.1 10.3 8 8 0 8 8 8 8 Ubiquitin-like domain TBK1_ULD PF18396.1 CDJ88167.1 - 4.7e-28 96.9 16.0 0.1 12.5 0.0 8.2 8 0 0 8 8 8 8 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CDJ88167.1 - 1.6e-26 92.5 26.1 0.08 13.3 0.1 8.1 8 0 0 8 8 8 8 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDJ88167.1 - 3.2e-25 88.4 14.2 0.31 11.2 0.0 9.1 8 0 0 8 8 8 8 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CDJ88167.1 - 7.1e-24 84.4 7.6 0.98 10.0 0.0 8.2 1 1 0 8 8 8 8 DUF2407 ubiquitin-like domain Big_7 PF17957.1 CDJ88167.1 - 1.2e-19 70.8 0.6 7.7 7.4 0.0 8.2 8 0 0 8 8 8 8 Bacterial Ig domain DUF2870 PF11069.8 CDJ88167.1 - 1.9e-11 44.2 0.0 70 3.9 0.0 8.8 8 0 0 8 8 8 0 Protein of unknown function (DUF2870) UDP-g_GGTase PF06427.11 CDJ88167.1 - 1e-09 38.5 16.5 11 6.1 0.0 7.8 8 0 0 8 8 8 0 UDP-glucose:Glycoprotein Glucosyltransferase Big_3_3 PF13750.6 CDJ88167.1 - 1.1e-09 38.1 0.1 60 3.2 0.0 7.7 8 0 0 8 8 8 0 Bacterial Ig-like domain (group 3) DUF3861 PF12977.7 CDJ88167.1 - 3.1e-08 33.7 14.3 41 4.4 0.0 8.1 8 0 0 8 8 8 0 Domain of Unknown Function with PDB structure (DUF3861) DUF969 PF06149.12 CDJ88167.1 - 3.5e-08 33.1 1.2 55 3.1 0.0 7.6 8 0 0 8 8 8 0 Protein of unknown function (DUF969) Ubiquitin_4 PF18036.1 CDJ88167.1 - 9.5e-08 32.0 58.9 40 4.4 0.2 15.7 16 0 0 16 16 16 0 Ubiquitin-like domain ORF11CD3 PF10549.9 CDJ88167.1 - 1.1e-06 28.7 0.0 2.2e+02 2.1 0.0 8.2 8 0 0 8 8 8 0 ORF11CD3 domain PDGLE PF13190.6 CDJ88167.1 - 3e-05 23.8 21.0 40 4.2 0.1 8.8 1 1 4 8 8 8 0 PDGLE domain ACT_5 PF13710.6 CDJ88167.1 - 0.00023 20.9 14.1 1e+02 2.8 0.0 8.0 8 0 0 8 8 8 0 ACT domain ProRS-C_2 PF09181.10 CDJ88167.1 - 0.079 13.1 19.3 1.8e+02 2.4 0.1 7.8 8 0 0 8 8 8 0 Prolyl-tRNA synthetase, C-terminal Grg1 PF11034.8 CDJ88168.1 - 0.27 11.5 1.5 8 6.8 0.1 2.7 3 0 0 3 3 3 0 Glucose-repressible protein Grg1 MM_CoA_mutase PF01642.22 CDJ88169.1 - 2.7e-141 471.6 10.2 1.8e-113 379.8 6.9 2.1 1 1 1 2 2 2 2 Methylmalonyl-CoA mutase B12-binding PF02310.19 CDJ88169.1 - 2.3e-14 53.5 0.3 7.3e-14 51.9 0.3 1.9 1 0 0 1 1 1 1 B12 binding domain SLT_L PF14718.6 CDJ88169.1 - 0.95 9.6 5.3 0.66 10.1 0.2 2.8 3 0 0 3 3 3 0 Soluble lytic murein transglycosylase L domain MM_CoA_mutase PF01642.22 CDJ88170.1 - 2.8e-243 808.1 0.3 3.4e-243 807.8 0.3 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 CDJ88170.1 - 2.3e-14 53.4 0.4 5.3e-14 52.3 0.4 1.6 1 0 0 1 1 1 1 B12 binding domain Thiolase_N PF00108.23 CDJ88171.1 - 8.6e-88 294.0 1.5 2.9e-87 292.3 1.9 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CDJ88171.1 - 9.2e-46 154.5 0.0 4.9e-45 152.2 0.0 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CDJ88171.1 - 0.00011 21.9 3.5 0.00018 21.2 1.4 2.3 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 CDJ88171.1 - 0.006 15.3 0.1 0.0095 14.7 0.1 1.4 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) Attractin PF08037.11 CDJ88171.1 - 0.096 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Attractin family zf-C2HC_2 PF13913.6 CDJ88174.1 - 2.2e-18 65.7 5.6 6.5e-10 38.7 0.6 2.2 2 0 0 2 2 2 2 zinc-finger of a C2HC-type DUF2318 PF10080.9 CDJ88174.1 - 0.00089 19.3 0.6 0.023 14.8 0.1 2.2 2 0 0 2 2 2 1 Predicted membrane protein (DUF2318) zf-RING_7 PF02591.15 CDJ88174.1 - 0.015 15.5 1.6 0.033 14.4 0.1 2.1 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf-C2H2_11 PF16622.5 CDJ88174.1 - 0.031 14.0 2.2 1.1 9.1 0.1 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type Sgf11 PF08209.11 CDJ88174.1 - 0.031 13.8 4.1 0.23 11.0 0.1 2.7 2 1 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DUF1178 PF06676.11 CDJ88174.1 - 0.048 14.0 0.6 0.077 13.4 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) zf-C2H2 PF00096.26 CDJ88174.1 - 0.062 13.8 1.7 0.65 10.6 0.1 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-HC5HC2H PF13771.6 CDJ88174.1 - 0.084 13.1 1.0 1.9 8.8 0.1 2.2 2 0 0 2 2 2 0 PHD-like zinc-binding domain zinc_ribbon_4 PF13717.6 CDJ88174.1 - 0.12 12.3 4.7 1.9 8.5 0.1 2.6 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_4 PF13894.6 CDJ88174.1 - 0.21 12.5 6.3 1.2 10.2 0.5 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger RNHCP PF12647.7 CDJ88174.1 - 0.29 11.1 3.4 2.7 8.0 2.4 2.2 1 1 1 2 2 2 0 RNHCP domain BACK PF07707.15 CDJ88175.1 - 1e-05 25.6 0.0 2.9e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch Rgp1 PF08737.10 CDJ88175.1 - 2.6 7.1 14.6 0.8 8.8 9.6 2.0 2 0 0 2 2 2 0 Rgp1 Dsh_C PF12316.8 CDJ88176.1 - 0.48 10.8 16.2 0.72 10.2 16.2 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Macoilin PF09726.9 CDJ88176.1 - 2.6 6.5 7.9 3.5 6.1 7.9 1.2 1 0 0 1 1 1 0 Macoilin family Bud13 PF09736.9 CDJ88176.1 - 5.8 7.3 14.8 0.84 10.0 9.7 1.9 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex DUF4551 PF15087.6 CDJ88176.1 - 8.1 5.1 10.8 9.7 4.9 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) MULE PF10551.9 CDJ88177.1 - 1.4e-10 41.4 0.0 3.7e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain DDOST_48kD PF03345.14 CDJ88180.1 - 5.2e-06 25.6 0.0 0.00028 19.8 0.0 2.1 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta ABC_transp_aux PF09822.9 CDJ88180.1 - 5.7e-06 26.0 0.0 1.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 ABC-type uncharacterized transport system zf-C3HC4 PF00097.25 CDJ88181.1 - 1.4e-06 28.0 24.1 0.0018 18.1 7.9 2.5 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ88181.1 - 0.00046 20.5 25.5 0.0022 18.3 7.8 2.8 2 1 0 2 2 2 2 Ring finger domain zf-RING_UBOX PF13445.6 CDJ88181.1 - 0.00068 19.6 16.2 1e+02 3.0 16.2 2.5 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDJ88181.1 - 0.0017 18.2 24.0 0.15 11.9 8.9 2.8 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ88181.1 - 0.0094 15.9 28.1 0.048 13.6 11.0 2.6 1 1 1 2 2 2 2 zinc-RING finger domain hSac2 PF12456.8 CDJ88181.1 - 0.035 13.8 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Inositol phosphatase AstB PF04996.12 CDJ88181.1 - 0.042 12.5 0.0 0.054 12.2 0.0 1.1 1 0 0 1 1 1 0 Succinylarginine dihydrolase zf-C3HC4_4 PF15227.6 CDJ88181.1 - 0.29 11.3 24.0 1.4 9.2 8.0 3.4 2 2 1 3 3 3 0 zinc finger of C3HC4-type, RING Retrotrans_gag PF03732.17 CDJ88182.1 - 0.05 13.9 0.0 0.057 13.7 0.0 1.1 1 0 0 1 1 1 0 Retrotransposon gag protein Neur_chan_LBD PF02931.23 CDJ88183.1 - 0.036 13.5 0.3 0.15 11.5 0.3 1.9 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel ligand binding domain Wzy_C PF04932.15 CDJ88183.1 - 1.1 8.9 3.6 0.53 9.9 0.2 2.1 3 0 0 3 3 3 0 O-Antigen ligase DUF3043 PF11241.8 CDJ88183.1 - 5.8 6.9 5.4 14 5.7 5.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) PIN_4 PF13638.6 CDJ88184.1 - 1.1e-16 61.3 0.5 4.3e-16 59.4 0.1 2.2 2 0 0 2 2 2 1 PIN domain PIN_9 PF18477.1 CDJ88184.1 - 0.018 15.4 1.0 0.27 11.6 0.0 3.0 3 0 0 3 3 3 0 PIN like domain EF1_GNE PF00736.19 CDJ88185.1 - 1.2e-33 115.1 0.9 1.2e-33 115.1 0.9 1.9 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 CDJ88185.1 - 1e-11 45.1 6.9 1e-11 45.1 6.9 2.8 3 0 0 3 3 2 1 Eukaryotic elongation factor 1 beta central acidic region HALZ PF02183.18 CDJ88185.1 - 0.00064 19.9 0.6 0.0014 18.8 0.6 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper bZIP_1 PF00170.21 CDJ88185.1 - 0.0011 19.1 1.3 0.0024 17.9 1.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor Spc7 PF08317.11 CDJ88185.1 - 0.0039 16.1 4.7 0.0052 15.7 4.7 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein FlaC_arch PF05377.11 CDJ88185.1 - 0.011 16.1 0.2 0.03 14.7 0.2 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 CDJ88185.1 - 0.056 13.2 1.2 0.14 12.0 1.2 1.6 1 0 0 1 1 1 0 Septum formation initiator YabA PF06156.13 CDJ88185.1 - 0.12 13.0 1.5 0.2 12.3 1.3 1.5 1 1 0 1 1 1 0 Initiation control protein YabA DUF3138 PF11336.8 CDJ88185.1 - 0.14 10.7 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Stm1_N PF09598.10 CDJ88185.1 - 0.22 12.4 0.5 0.22 12.4 0.5 1.9 2 0 0 2 2 2 0 Stm1 ZapB PF06005.12 CDJ88185.1 - 7.6 7.0 9.6 24 5.5 9.6 1.9 1 1 0 1 1 1 0 Cell division protein ZapB PIN_4 PF13638.6 CDJ88186.1 - 4.4e-18 65.8 0.1 1.1e-17 64.5 0.0 1.7 2 0 0 2 2 2 1 PIN domain WW PF00397.26 CDJ88186.1 - 3.7e-06 26.9 0.0 1.5e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 WW domain NBD94 PF16830.5 CDJ88186.1 - 0.21 12.0 4.5 0.65 10.4 0.1 2.8 3 0 0 3 3 3 0 Nucleotide-Binding Domain 94 of RH ICAT PF06384.11 CDJ88187.1 - 2.7e-10 40.3 0.7 2.7e-10 40.3 0.7 2.1 2 0 0 2 2 2 1 Beta-catenin-interacting protein ICAT DMAP_binding PF06464.11 CDJ88187.1 - 0.00019 22.2 6.2 0.0012 19.6 0.5 2.3 2 0 0 2 2 2 1 DMAP1-binding Domain GvpG PF05120.12 CDJ88187.1 - 0.00059 19.8 10.6 0.00085 19.3 0.9 2.2 2 0 0 2 2 2 1 Gas vesicle protein G DUF1104 PF06518.11 CDJ88187.1 - 0.0007 19.9 5.5 0.15 12.5 0.4 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1104) FANCI_S4 PF14678.6 CDJ88187.1 - 0.0039 16.3 0.4 0.0069 15.5 0.4 1.3 1 0 0 1 1 1 1 FANCI solenoid 4 FlxA PF14282.6 CDJ88187.1 - 0.012 15.6 1.9 0.012 15.6 1.9 2.2 2 1 0 2 2 2 0 FlxA-like protein CAMP_factor PF07373.11 CDJ88187.1 - 0.023 14.3 0.5 0.023 14.3 0.5 1.5 1 1 1 2 2 2 0 CAMP factor (Cfa) DUF2664 PF10867.8 CDJ88187.1 - 0.028 14.8 1.0 0.09 13.2 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2664) TraF_2 PF13729.6 CDJ88187.1 - 0.089 12.2 0.4 0.093 12.1 0.4 1.2 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein Occludin_ELL PF07303.13 CDJ88187.1 - 0.32 11.7 5.4 2.4 9.0 0.4 2.2 2 0 0 2 2 2 0 Occludin homology domain DUF883 PF05957.13 CDJ88187.1 - 1 10.0 8.6 0.3 11.7 3.2 2.3 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) PRP1_N PF06424.12 CDJ88187.1 - 1.2 9.5 5.7 0.56 10.6 0.6 2.1 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DASH_Hsk3 PF08227.11 CDJ88187.1 - 2.7 8.4 6.4 6.4 7.2 1.9 3.0 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like FtsJ PF01728.19 CDJ88188.1 - 6.4e-35 120.8 0.0 1.2e-34 120.0 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase G-patch PF01585.23 CDJ88188.1 - 8.3e-12 44.8 1.4 1.6e-11 43.9 1.4 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CDJ88188.1 - 0.0025 17.9 0.5 0.005 16.9 0.5 1.5 1 0 0 1 1 1 1 G-patch domain PH_4 PF15404.6 CDJ88190.1 - 0.048 13.5 0.3 0.064 13.0 0.2 1.3 1 1 0 1 1 1 0 Pleckstrin homology domain Kunitz_BPTI PF00014.23 CDJ88191.1 - 8.5e-22 77.2 15.5 1.1e-12 48.0 3.3 2.7 3 0 0 3 3 3 2 Kunitz/Bovine pancreatic trypsin inhibitor domain SPAN-X PF07458.12 CDJ88191.1 - 0.07 13.6 0.2 0.12 12.8 0.2 1.3 1 0 0 1 1 1 0 Sperm protein associated with nucleus, mapped to X chromosome Granulin PF00396.18 CDJ88191.1 - 1.1 9.7 13.4 17 5.9 9.5 3.5 2 1 1 3 3 3 0 Granulin ABC_tran PF00005.27 CDJ88192.2 - 9.6e-50 168.7 1.6 1.4e-25 90.4 0.0 3.2 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 CDJ88192.2 - 1.4e-14 54.6 9.2 0.0017 18.2 0.0 4.3 2 2 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDJ88192.2 - 2.8e-11 43.3 1.3 0.0062 16.0 0.0 4.1 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CDJ88192.2 - 9.2e-08 32.2 0.2 0.0015 18.3 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.6 CDJ88192.2 - 2.6e-06 27.5 0.0 0.017 15.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CDJ88192.2 - 4.5e-06 27.1 0.1 0.12 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 CDJ88192.2 - 4.9e-06 26.6 2.2 0.019 14.9 0.0 3.0 3 0 0 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 CDJ88192.2 - 5.4e-06 26.1 1.1 0.01 15.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 CDJ88192.2 - 1.6e-05 25.2 0.2 0.088 13.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CDJ88192.2 - 2.2e-05 24.8 0.6 0.39 11.0 0.0 2.9 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 CDJ88192.2 - 3.6e-05 23.8 1.7 0.0029 17.7 0.5 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase NB-ARC PF00931.22 CDJ88192.2 - 5.3e-05 22.5 0.0 0.25 10.5 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_24 PF13479.6 CDJ88192.2 - 5.7e-05 22.9 1.6 0.23 11.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 CDJ88192.2 - 0.00011 22.8 3.8 0.17 12.4 0.1 3.8 4 1 0 4 4 3 2 AAA domain NACHT PF05729.12 CDJ88192.2 - 0.00015 21.7 3.4 0.16 11.9 0.1 2.8 2 1 1 3 3 3 2 NACHT domain AAA_33 PF13671.6 CDJ88192.2 - 0.00017 21.7 0.5 0.38 10.9 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA PF00004.29 CDJ88192.2 - 0.00024 21.6 0.1 0.064 13.7 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CDJ88192.2 - 0.00052 19.8 2.8 0.1 12.3 0.1 3.1 2 2 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 CDJ88192.2 - 0.00071 19.9 0.5 1.1 9.7 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_25 PF13481.6 CDJ88192.2 - 0.0012 18.5 0.2 2.3 7.8 0.0 3.2 3 1 0 3 3 3 2 AAA domain cobW PF02492.19 CDJ88192.2 - 0.0046 16.6 0.3 0.27 10.8 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 CDJ88192.2 - 0.0048 16.8 2.8 2.9 7.8 0.1 3.3 2 1 0 2 2 2 1 NTPase ATPase_2 PF01637.18 CDJ88192.2 - 0.012 15.6 0.0 0.53 10.2 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 CDJ88192.2 - 0.016 14.8 0.2 8.3 5.9 0.0 2.9 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_5 PF07728.14 CDJ88192.2 - 0.018 15.0 0.5 5.3 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Roc PF08477.13 CDJ88192.2 - 0.023 14.9 5.5 2.2 8.5 0.0 3.5 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase OMP_b-brl PF13505.6 CDJ88192.2 - 0.039 14.1 0.7 2 8.5 0.5 2.4 2 0 0 2 2 2 0 Outer membrane protein beta-barrel domain SRP54 PF00448.22 CDJ88192.2 - 0.043 13.5 1.8 4.7 6.8 0.1 2.9 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 CDJ88192.2 - 0.052 13.9 0.2 5.4 7.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 CDJ88192.2 - 0.061 13.0 0.0 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.9 CDJ88192.2 - 0.065 13.0 0.1 15 5.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 CDJ88192.2 - 0.086 13.3 21.5 0.12 12.9 0.1 4.2 3 2 0 3 3 2 0 AAA domain SbcCD_C PF13558.6 CDJ88192.2 - 0.098 12.9 0.6 4.4 7.6 0.2 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit FeoB_N PF02421.18 CDJ88192.2 - 0.12 11.9 0.2 1.9 8.0 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B MobB PF03205.14 CDJ88192.2 - 0.13 12.1 0.9 23 4.9 0.0 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF3987 PF13148.6 CDJ88192.2 - 0.3 10.0 2.1 7.7 5.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) Dynamin_N PF00350.23 CDJ88192.2 - 0.51 10.4 2.8 4 7.5 0.0 3.1 2 1 0 3 3 3 0 Dynamin family DUF87 PF01935.17 CDJ88192.2 - 0.69 10.0 0.0 0.69 10.0 0.0 3.0 4 0 0 4 4 3 0 Helicase HerA, central domain WD40 PF00400.32 CDJ88194.1 - 0.0031 18.3 4.1 0.47 11.4 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat SART-1 PF03343.13 CDJ88195.1 - 1.1e-106 357.8 69.2 1.1e-106 357.8 69.2 2.2 2 0 0 2 2 2 1 SART-1 family HA PF03457.14 CDJ88195.1 - 0.092 13.1 1.6 0.64 10.4 0.1 3.1 2 0 0 2 2 2 0 Helicase associated domain FbpA PF05833.11 CDJ88196.1 - 0.12 11.2 0.0 0.64 8.7 0.0 1.9 2 0 0 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) LMF1 PF06762.14 CDJ88198.1 - 2.4e-58 198.3 5.2 2.7e-58 198.1 5.2 1.1 1 0 0 1 1 1 1 Lipase maturation factor MMR_HSR1 PF01926.23 CDJ88199.1 - 6.5e-17 61.7 0.1 4.4e-16 59.0 0.1 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ88199.1 - 1.5e-08 34.4 0.1 2.4e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CDJ88199.1 - 5e-07 29.5 0.0 0.00022 20.8 0.0 3.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDJ88199.1 - 3e-05 24.0 0.2 0.086 12.7 0.1 2.9 3 0 0 3 3 3 2 RsgA GTPase Ras PF00071.22 CDJ88199.1 - 0.00013 21.6 0.2 0.0087 15.7 0.0 2.9 1 1 1 2 2 2 1 Ras family Roc PF08477.13 CDJ88199.1 - 0.0061 16.8 0.1 0.045 14.0 0.0 2.3 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CDJ88199.1 - 0.0075 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 CDJ88199.1 - 0.011 15.8 2.3 1.2 9.2 0.6 2.5 1 1 1 2 2 2 0 Dynamin family KH_2 PF07650.17 CDJ88199.1 - 0.011 15.5 0.4 0.026 14.3 0.4 1.6 1 0 0 1 1 1 0 KH domain ATP_bind_1 PF03029.17 CDJ88199.1 - 0.027 14.3 0.1 0.16 11.7 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 CDJ88199.1 - 0.052 13.9 0.3 0.24 11.7 0.3 2.3 1 1 0 1 1 1 0 AAA ATPase domain MnmE_helical PF12631.7 CDJ88199.1 - 0.057 13.6 0.0 0.1 12.8 0.0 1.6 1 1 0 1 1 1 0 MnmE helical domain RS4NT PF08071.12 CDJ88199.1 - 0.094 12.8 0.3 0.2 11.8 0.3 1.5 1 0 0 1 1 1 0 RS4NT (NUC023) domain SLIDE PF09111.10 CDJ88199.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 SLIDE His_Phos_2 PF00328.22 CDJ88200.1 - 1e-13 51.4 0.4 3.5e-10 39.8 0.4 3.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) FtsL PF04999.13 CDJ88200.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Cell division protein FtsL RPAP1_N PF08621.10 CDJ88200.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 RPAP1-like, N-terminal DCX PF03607.17 CDJ88202.1 - 0.0046 17.0 0.0 0.0071 16.4 0.0 1.4 1 0 0 1 1 1 1 Doublecortin PUF PF00806.19 CDJ88203.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat MARVEL PF01284.23 CDJ88204.1 - 0.00012 22.1 17.9 0.0002 21.4 17.9 1.3 1 1 0 1 1 1 1 Membrane-associating domain DUF2070 PF09843.9 CDJ88204.1 - 0.044 12.1 5.2 0.052 11.8 5.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Moulting_cycle PF04870.16 CDJ88205.1 - 1.8e-13 50.5 1.5 1.8e-13 50.5 1.5 3.1 2 2 1 3 3 3 1 Moulting cycle Arrestin_N PF00339.29 CDJ88207.1 - 8.1e-34 116.8 0.0 1.9e-30 105.8 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CDJ88207.1 - 1.6e-27 96.5 0.0 2.8e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain GST_N_3 PF13417.6 CDJ88209.1 - 7.4e-20 71.1 0.1 2.1e-19 69.7 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CDJ88209.1 - 1.2e-15 57.6 0.0 3.8e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDJ88209.1 - 2e-15 56.8 0.0 3.6e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CDJ88209.1 - 1.6e-05 25.0 0.0 3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDJ88209.1 - 0.00012 22.2 0.0 0.00024 21.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 CDJ88209.1 - 0.028 14.7 0.0 0.051 13.9 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein PAP2_C PF14360.6 CDJ88210.1 - 6.2e-22 77.9 6.7 6.2e-22 77.9 6.7 2.8 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 CDJ88210.1 - 7.1e-05 22.6 2.3 7.1e-05 22.6 2.3 2.7 3 1 0 3 3 3 1 PAP2 superfamily DUF3796 PF12676.7 CDJ88210.1 - 0.32 11.4 3.2 0.54 10.7 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3796) PAP2_3 PF14378.6 CDJ88210.1 - 0.68 9.6 17.9 0.077 12.7 13.0 1.9 2 0 0 2 2 2 0 PAP2 superfamily Baculo_VP91_N PF08475.10 CDJ88212.1 - 0.0028 17.4 0.4 0.0044 16.7 0.4 1.3 1 0 0 1 1 1 1 Viral capsid protein 91 N-terminal Tubulin PF00091.25 CDJ88214.1 - 9e-72 241.4 0.0 1.4e-71 240.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDJ88214.1 - 3.6e-44 150.0 0.1 5.7e-44 149.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CDJ88214.1 - 7.6e-07 29.5 0.0 1.8e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CDJ88214.1 - 0.012 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 CDJ88214.1 - 0.019 14.2 0.0 0.047 12.9 0.0 1.6 2 0 0 2 2 2 0 Tubulin like Acyl_transf_1 PF00698.21 CDJ88215.1 - 0.046 13.2 0.4 0.089 12.3 0.3 1.5 1 1 1 2 2 2 0 Acyl transferase domain XPC-binding PF09280.11 CDJ88215.1 - 0.075 12.8 0.0 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 XPC-binding domain Pkinase_Tyr PF07714.17 CDJ88216.1 - 2.4e-21 76.2 0.0 3.9e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ88216.1 - 1.4e-17 63.9 0.0 3.6e-17 62.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Peptidase_M85 PF13678.6 CDJ88216.1 - 0.025 14.2 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 NFkB-p65-degrading zinc protease TMEM154 PF15102.6 CDJ88217.1 - 0.0094 15.9 0.1 0.0094 15.9 0.1 2.8 3 0 0 3 3 3 1 TMEM154 protein family TFIIIC_delta PF12657.7 CDJ88217.1 - 0.057 13.4 1.3 0.21 11.5 0.0 2.5 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term RPE65 PF03055.15 CDJ88218.1 - 2.1e-55 188.7 0.0 3.2e-55 188.2 0.0 1.2 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein RabGAP-TBC PF00566.18 CDJ88219.1 - 1.1e-40 139.6 1.6 1.6e-40 139.1 1.6 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 CDJ88219.1 - 5.5e-07 29.2 0.2 0.01 15.3 0.0 2.6 2 0 0 2 2 2 2 Rab-binding domain (RBD) 7tm_1 PF00001.21 CDJ88220.1 - 2.6e-13 49.9 17.8 3.5e-13 49.5 17.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDJ88220.1 - 1.4e-09 37.7 12.0 2.3e-09 37.0 12.0 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 CDJ88220.1 - 0.0019 17.6 15.8 0.01 15.2 15.8 2.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 CDJ88220.1 - 0.004 16.9 8.3 0.006 16.4 8.1 1.6 1 1 0 1 1 1 1 Olfactory receptor Pkinase PF00069.25 CDJ88222.1 - 1e-74 251.2 0.0 1.5e-74 250.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ88222.1 - 1.1e-43 149.5 0.0 1.9e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 CDJ88222.1 - 2.2e-12 47.4 0.1 2.8e-11 43.9 0.0 2.8 2 1 0 2 2 2 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 CDJ88222.1 - 8.8e-08 31.8 0.0 1.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CDJ88222.1 - 0.00076 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CDJ88222.1 - 0.017 15.1 0.3 0.036 14.0 0.3 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDJ88222.1 - 0.029 13.3 1.4 0.073 12.0 0.1 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 CDJ88222.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NUDE_C PF04880.13 CDJ88222.1 - 0.17 12.3 2.8 0.68 10.4 0.0 2.2 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region ATP_bind_3 PF01171.20 CDJ88223.1 - 0.056 13.2 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 PP-loop family DUF2540 PF10802.8 CDJ88224.1 - 0.074 13.1 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) DivIC PF04977.15 CDJ88225.1 - 0.00029 20.6 0.1 0.072 12.9 0.0 2.4 2 0 0 2 2 2 2 Septum formation initiator Exo_endo_phos_2 PF14529.6 CDJ88225.1 - 0.14 12.0 0.0 0.63 9.9 0.0 2.1 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase zf-H2C2_2 PF13465.6 CDJ88226.1 - 5.1e-48 159.4 87.3 1.3e-08 34.9 0.4 11.6 12 0 0 12 12 12 8 Zinc-finger double domain zf-C2H2 PF00096.26 CDJ88226.1 - 3.4e-41 137.4 80.1 4e-06 27.0 0.6 11.3 10 1 1 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ88226.1 - 1.8e-28 96.7 82.7 0.00057 20.5 0.5 11.3 10 1 1 11 11 11 9 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDJ88226.1 - 2.3e-05 24.3 9.5 0.00035 20.5 2.3 10.8 10 1 1 11 11 11 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ88226.1 - 2.4e-05 24.5 65.2 0.0077 16.5 0.1 10.8 11 0 0 11 11 11 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDJ88226.1 - 0.00014 22.1 65.8 0.79 10.2 0.5 10.7 10 1 1 11 11 11 6 Zinc-finger of C2H2 type zf-Di19 PF05605.12 CDJ88226.1 - 0.0019 18.5 4.6 0.0019 18.5 4.6 6.9 4 2 2 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 CDJ88226.1 - 0.048 14.3 33.3 1.1 10.0 1.3 7.6 2 2 6 8 8 8 0 Zinc finger C2H2-type, 3 repeats FYVE PF01363.21 CDJ88226.1 - 0.45 10.7 52.3 1.1e+02 3.1 21.7 5.6 2 2 2 4 4 4 0 FYVE zinc finger Acetone_carb_G PF08882.11 CDJ88226.1 - 0.49 10.6 4.3 6.4 7.0 0.6 3.0 2 1 0 2 2 2 0 Acetone carboxylase gamma subunit PyrI_C PF02748.15 CDJ88226.1 - 1.3 8.9 47.7 0.22 11.5 0.7 8.1 8 0 0 8 8 8 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain HalOD2 PF18547.1 CDJ88226.1 - 2.1 8.3 9.6 12 5.9 0.2 4.1 3 1 0 3 3 3 0 Halobacterial output domain 2 PAN_1 PF00024.26 CDJ88227.1 - 1.5e-17 63.3 6.2 2.4e-08 33.8 0.2 2.1 1 1 1 2 2 2 2 PAN domain PAN_1 PF00024.26 CDJ88228.1 - 1.8e-07 31.0 4.0 0.00026 20.9 0.3 2.3 1 1 1 2 2 2 2 PAN domain Mucin PF01456.17 CDJ88229.1 - 0.45 10.5 17.4 0.58 10.1 17.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Tir_receptor_C PF07489.11 CDJ88229.1 - 1.1 9.2 7.3 1.6 8.6 7.3 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus CC PF04942.14 CDJ88230.1 - 0.0034 17.5 13.7 0.0068 16.6 13.7 1.4 1 0 0 1 1 1 1 CC domain Ground-like PF04155.18 CDJ88231.1 - 9.4e-17 61.4 0.3 1.4e-16 60.9 0.3 1.3 1 0 0 1 1 1 1 Ground-like domain MFS_1 PF07690.16 CDJ88232.1 - 2.9e-32 112.0 34.5 1.6e-29 102.9 24.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SapB_2 PF03489.17 CDJ88233.1 - 1.8e-18 66.4 11.0 2.9e-08 33.7 0.9 6.0 6 0 0 6 6 6 4 Saposin-like type B, region 2 SapB_1 PF05184.15 CDJ88233.1 - 3.9e-06 26.8 13.7 8.5e-05 22.5 1.5 5.2 5 0 0 5 5 5 2 Saposin-like type B, region 1 PA28_alpha PF02251.18 CDJ88233.1 - 0.00079 19.4 0.0 0.013 15.5 0.0 2.5 2 0 0 2 2 2 1 Proteasome activator pa28 alpha subunit DUF445 PF04286.12 CDJ88233.1 - 0.25 11.1 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Pkinase PF00069.25 CDJ88234.1 - 3.3e-71 239.8 0.1 3.7e-71 239.6 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ88234.1 - 2.3e-38 132.0 0.2 5.7e-38 130.7 0.2 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ88234.1 - 5.4e-05 22.3 0.4 0.00033 19.7 0.4 1.9 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CDJ88234.1 - 0.0017 18.3 0.0 0.0039 17.1 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ88234.1 - 0.0034 16.8 0.1 0.0062 15.9 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDJ88234.1 - 0.0046 16.3 0.1 0.056 12.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 CDJ88234.1 - 0.034 13.2 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RhoGEF PF00621.20 CDJ88235.1 - 2.2e-26 93.2 0.0 3.3e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 CDJ88235.1 - 7e-23 81.2 0.0 1.9e-22 79.7 0.0 1.6 2 0 0 2 2 2 1 Pleckstrin homology domain FA_desaturase PF00487.24 CDJ88236.1 - 1.6e-24 87.2 17.4 1.6e-24 87.2 17.4 1.5 1 1 1 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.8 CDJ88236.1 - 2.1e-05 24.7 0.0 3.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) CrgA PF06781.12 CDJ88236.1 - 0.096 12.8 0.1 1.3 9.2 0.1 2.3 2 0 0 2 2 2 0 Cell division protein CrgA DUF3399 PF11879.8 CDJ88236.1 - 0.32 11.4 1.4 0.61 10.4 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) Fungus-induced PF10917.8 CDJ88237.1 - 0.19 12.1 0.3 0.19 12.1 0.3 2.3 2 1 1 3 3 3 0 Fungus-induced protein TTR-52 PF01060.23 CDJ88238.1 - 1e-23 83.8 0.0 1.3e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Transthyretin-like family DUF1416 PF07210.12 CDJ88238.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) Pkinase_Tyr PF07714.17 CDJ88239.1 - 5.2e-22 78.4 0.0 7.1e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ88239.1 - 4.5e-19 68.8 0.0 6.3e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EST1_DNA_bind PF10373.9 CDJ88239.1 - 1.8e-07 31.0 0.0 2.6e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain TPR_17 PF13431.6 CDJ88239.1 - 0.11 13.0 0.1 4.5 7.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Kinase-like PF14531.6 CDJ88239.1 - 0.16 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like SET PF00856.28 CDJ88240.1 - 1.4e-10 41.8 1.3 1.4e-10 41.8 1.3 2.6 2 1 0 2 2 2 1 SET domain preSET_CXC PF18264.1 CDJ88240.1 - 1.9e-09 37.8 21.5 1.9e-09 37.8 21.5 2.9 2 0 0 2 2 2 1 CXC domain RabGAP-TBC PF00566.18 CDJ88241.1 - 3e-16 59.7 1.1 4.2e-16 59.3 1.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain NIF PF03031.18 CDJ88242.1 - 2.6e-56 189.7 0.4 3.2e-56 189.4 0.4 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 CDJ88242.1 - 0.18 12.2 0.2 2 8.8 0.0 2.2 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase AAA PF00004.29 CDJ88243.1 - 8.2e-13 48.9 0.0 1.7e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ88243.1 - 1.5e-11 44.7 0.0 3e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ88243.1 - 1.5e-10 41.7 0.2 2.3e-08 34.6 0.2 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CDJ88243.1 - 1.3e-06 28.5 0.0 5.2e-06 26.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 CDJ88243.1 - 1.2e-05 25.7 0.0 0.00012 22.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 CDJ88243.1 - 0.00028 20.8 0.0 0.00044 20.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 CDJ88243.1 - 0.00032 20.5 0.0 0.00058 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 CDJ88243.1 - 0.00054 19.7 0.0 0.0013 18.5 0.0 1.5 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_7 PF12775.7 CDJ88243.1 - 0.0013 18.3 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region ATPase_2 PF01637.18 CDJ88243.1 - 0.0043 17.0 0.0 0.82 9.5 0.0 2.2 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_lid_10 PF17872.1 CDJ88243.1 - 0.0049 17.0 0.3 0.06 13.5 0.0 2.6 1 1 1 2 2 2 1 AAA lid domain RuvB_N PF05496.12 CDJ88243.1 - 0.0053 16.5 0.1 0.49 10.1 0.0 2.5 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 CDJ88243.1 - 0.0057 16.1 0.0 0.02 14.3 0.0 1.7 1 1 0 1 1 1 1 Bacterial TniB protein Zeta_toxin PF06414.12 CDJ88243.1 - 0.0061 15.9 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin NTPase_1 PF03266.15 CDJ88243.1 - 0.047 13.6 0.0 0.7 9.8 0.0 2.3 1 1 1 2 2 2 0 NTPase SR-25 PF10500.9 CDJ88243.1 - 0.068 12.8 6.1 0.11 12.1 6.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ResIII PF04851.15 CDJ88243.1 - 0.11 12.5 0.0 0.5 10.3 0.0 1.9 1 1 2 3 3 3 0 Type III restriction enzyme, res subunit TIP49 PF06068.13 CDJ88243.1 - 0.11 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain UPF0113_N PF17833.1 CDJ88244.1 - 5.8e-32 110.1 0.0 8.5e-32 109.6 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 CDJ88244.1 - 1.7e-23 82.7 0.0 2.7e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 CDJ88244.1 - 0.007 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 PUA domain ERCC4 PF02732.15 CDJ88245.1 - 2.5e-19 70.0 0.0 6.1e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain PAH PF02671.21 CDJ88245.1 - 0.1 12.7 0.8 17 5.7 0.1 3.0 3 0 0 3 3 3 0 Paired amphipathic helix repeat WW PF00397.26 CDJ88246.1 - 6.5e-10 38.9 0.9 2.3e-09 37.2 0.9 2.0 1 0 0 1 1 1 1 WW domain DUF5344 PF17279.2 CDJ88247.1 - 0.07 13.7 0.8 0.48 11.0 0.1 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5344) YicC_N PF03755.13 CDJ88247.1 - 0.48 10.9 8.0 0.26 11.8 1.3 3.3 2 1 2 4 4 4 0 YicC-like family, N-terminal region DUF2703 PF10865.8 CDJ88247.1 - 0.49 10.6 2.6 1.9 8.7 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2703) DUF725 PF05267.12 CDJ88247.1 - 1 9.4 5.5 9.9 6.2 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF725) Baculo_PEP_C PF04513.12 CDJ88247.1 - 1.2 9.1 18.2 0.99 9.4 0.9 4.6 3 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Baculo_p24 PF05073.12 CDJ88247.1 - 3.4 7.4 7.2 2.6 7.8 0.2 3.0 3 0 0 3 3 3 0 Baculovirus P24 capsid protein COG5 PF10392.9 CDJ88247.1 - 5.3 7.2 15.6 0.059 13.5 1.4 4.0 4 1 1 5 5 5 0 Golgi transport complex subunit 5 GTP_EFTU PF00009.27 CDJ88248.1 - 6.2e-51 172.7 0.1 9.1e-51 172.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CDJ88248.1 - 7.2e-16 58.4 2.2 1.6e-15 57.2 2.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 CDJ88248.1 - 2.2e-08 34.4 0.0 1.2e-07 32.0 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 CDJ88248.1 - 3.3e-05 23.9 0.1 6.2e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ88248.1 - 0.034 14.0 0.5 0.1 12.5 0.2 1.9 1 1 1 2 2 2 0 RsgA GTPase cobW PF02492.19 CDJ88248.1 - 0.052 13.1 0.6 0.14 11.7 0.1 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain S36_mt PF10937.8 CDJ88249.1 - 1e-08 36.7 1.6 7.6e-06 27.5 0.2 2.1 1 1 1 2 2 2 2 Ribosomal protein S36, mitochondrial DUF2600 PF10776.9 CDJ88250.1 - 0.11 11.4 0.1 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) Sterol-sensing PF12349.8 CDJ88251.1 - 3.7e-14 52.8 36.8 4e-11 43.0 15.8 2.8 2 1 1 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 CDJ88251.1 - 9.7e-08 31.3 9.2 9.7e-08 31.3 9.2 2.5 2 0 0 2 2 2 1 MMPL family Patched PF02460.18 CDJ88251.1 - 2.6e-06 25.9 41.1 0.00089 17.5 15.9 2.3 2 0 0 2 2 2 2 Patched family Tom37 PF10568.9 CDJ88252.1 - 4.3e-29 101.4 0.1 7.6e-29 100.6 0.1 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 CDJ88252.1 - 1.8e-22 78.9 0.1 4.3e-22 77.7 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 CDJ88252.1 - 3.4e-12 47.0 0.0 7.3e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 CDJ88252.1 - 0.00034 20.6 0.0 0.00064 19.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDJ88252.1 - 0.0021 18.2 0.0 0.015 15.4 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDJ88252.1 - 0.014 15.6 0.0 0.046 14.0 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain zf-HC2 PF13490.6 CDJ88252.1 - 0.025 14.8 0.9 6.5 7.1 0.0 2.7 3 0 0 3 3 3 0 Putative zinc-finger Amidinotransf PF02274.17 CDJ88252.1 - 0.14 11.2 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Amidinotransferase zf-LITAF-like PF10601.9 CDJ88253.1 - 2.9e-20 72.3 14.3 4e-20 71.9 14.3 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-LITAF-like PF10601.9 CDJ88254.1 - 3.3e-22 78.5 0.6 4.1e-22 78.2 0.6 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Zn_Tnp_IS1 PF03811.13 CDJ88254.1 - 0.00098 18.8 1.7 0.22 11.3 0.1 2.3 2 0 0 2 2 2 2 InsA N-terminal domain Inhibitor_I67 PF11405.8 CDJ88254.1 - 0.028 14.7 0.9 0.069 13.4 0.1 1.9 2 0 0 2 2 2 0 Bromelain inhibitor VI DUF983 PF06170.12 CDJ88254.1 - 0.056 13.9 4.8 0.17 12.3 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF983) zf-ribbon_3 PF13248.6 CDJ88254.1 - 0.068 12.6 1.9 2.3 7.7 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 CDJ88254.1 - 0.082 13.0 1.4 5.5 7.2 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Anti-TRAP PF15777.5 CDJ88254.1 - 0.11 12.5 0.2 5.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zinc_ribbon_10 PF10058.9 CDJ88254.1 - 0.22 11.3 1.9 1.4 8.7 0.6 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Rubredoxin_2 PF18073.1 CDJ88254.1 - 0.48 10.2 6.6 0.42 10.4 0.6 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain DHHC PF01529.20 CDJ88254.1 - 1.6 8.9 8.3 0.9 9.7 1.1 2.1 1 1 1 2 2 2 0 DHHC palmitoyltransferase Ribosomal_S26e PF01283.19 CDJ88255.1 - 7.9e-51 171.0 9.5 9.2e-51 170.8 9.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DsbC PF11412.8 CDJ88255.1 - 0.052 13.6 0.1 0.068 13.2 0.1 1.2 1 0 0 1 1 1 0 Disulphide bond corrector protein DsbC DnaJ_C PF01556.18 CDJ88256.1 - 9.6e-42 142.6 0.4 1.3e-41 142.1 0.4 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CDJ88256.1 - 1.1e-14 54.5 14.4 2.3e-14 53.5 14.4 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CDJ88256.1 - 0.0023 17.9 10.8 0.26 11.3 1.4 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein DnaJ PF00226.31 CDJ88256.1 - 0.011 15.9 0.1 0.025 14.7 0.1 1.6 1 0 0 1 1 1 0 DnaJ domain HypA PF01155.19 CDJ88256.1 - 9.7 6.3 9.9 20 5.2 0.6 2.4 1 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CAP PF00188.26 CDJ88257.1 - 2.9e-14 54.0 5.4 4.7e-14 53.3 5.4 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ88257.1 - 0.0026 18.0 2.2 0.017 15.4 2.2 2.1 1 1 0 1 1 1 1 Ancylostoma-associated secreted protein related Ldl_recept_a PF00057.18 CDJ88258.1 - 4.2e-08 33.3 7.5 4.2e-08 33.3 7.5 2.3 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 CDJ88259.1 - 8.3e-15 54.7 13.7 1.3e-07 31.7 3.4 2.1 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A HTH_Tnp_IS630 PF01710.16 CDJ88260.1 - 3.3e-07 30.4 0.1 5e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 CDJ88260.1 - 3.2e-06 27.3 0.3 5.5e-06 26.5 0.3 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 CDJ88260.1 - 0.00022 21.7 0.0 0.00052 20.6 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_48 PF17906.1 CDJ88260.1 - 0.00064 19.8 0.5 0.00064 19.8 0.5 2.1 2 0 0 2 2 2 1 HTH domain in Mos1 transposase HTH_23 PF13384.6 CDJ88260.1 - 0.00068 19.4 0.0 0.49 10.3 0.0 2.4 2 0 0 2 2 2 2 Homeodomain-like domain HTH_38 PF13936.6 CDJ88260.1 - 0.0024 17.6 0.0 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 CDJ88260.1 - 0.0036 17.4 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_50 PF18024.1 CDJ88260.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 CDJ88260.1 - 0.028 13.8 0.3 0.47 9.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 CDJ88260.1 - 0.035 14.0 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 HTH domain HTH_40 PF14493.6 CDJ88260.1 - 0.069 13.6 0.1 0.12 12.9 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF488 PF04343.13 CDJ88260.1 - 0.13 12.9 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF488 DUF4429 PF14472.6 CDJ88263.1 - 0.9 10.2 4.6 1.4 9.5 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4429) DUF1866 PF08952.11 CDJ88264.1 - 5.2e-16 58.8 0.0 8e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1866) Exo_endo_phos PF03372.23 CDJ88264.1 - 1.6e-13 50.7 0.8 3.5e-13 49.6 0.2 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family UPF0449 PF15136.6 CDJ88265.1 - 0.0038 17.7 0.0 0.77 10.3 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family UPF0449 GPS2_interact PF15784.5 CDJ88265.1 - 0.045 14.2 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain GyrB_insert PF18053.1 CDJ88265.1 - 0.15 11.9 0.1 0.46 10.4 0.0 1.7 2 0 0 2 2 2 0 DNA gyrase B subunit insert domain DASH_Dad3 PF08656.10 CDJ88265.1 - 0.16 12.1 1.7 0.72 10.0 0.2 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad3 HAD_2 PF13419.6 CDJ88266.1 - 0.0016 18.5 0.0 0.0099 16.0 0.0 1.9 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Iso_dh PF00180.20 CDJ88267.1 - 4.6e-74 249.6 0.0 5.8e-74 249.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ABC2_membrane_3 PF12698.7 CDJ88268.1 - 4.1e-14 52.4 11.0 1.1e-13 51.0 11.0 1.8 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 CDJ88268.1 - 0.32 10.4 14.9 1.7 8.0 9.6 2.4 2 1 0 2 2 2 0 ABC-2 type transporter ABC_tran PF00005.27 CDJ88269.1 - 9.2e-52 175.2 0.0 1.6e-28 99.9 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CDJ88269.1 - 1.3e-30 106.7 15.8 2.1e-30 106.0 15.8 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 CDJ88269.1 - 1.4e-20 74.4 0.7 7.1e-06 26.1 0.0 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDJ88269.1 - 4e-06 26.4 0.0 2.7 7.4 0.0 3.8 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CDJ88269.1 - 3.6e-05 23.4 1.0 0.15 11.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 CDJ88269.1 - 0.00024 21.7 11.1 0.077 13.5 0.9 3.3 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 CDJ88269.1 - 0.0034 17.4 0.0 2.7 8.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 CDJ88269.1 - 0.0041 16.9 0.1 7.9 6.1 0.1 3.2 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 CDJ88269.1 - 0.011 15.6 0.4 0.75 9.7 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase SbcCD_C PF13558.6 CDJ88269.1 - 0.024 14.9 0.0 8.7 6.7 0.0 3.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 CDJ88269.1 - 0.026 14.2 2.4 1.2 8.7 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 CDJ88269.1 - 0.031 13.5 0.1 5.4 6.2 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_27 PF13514.6 CDJ88269.1 - 0.14 11.7 0.1 8.2 6.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 CDJ88269.1 - 0.19 11.5 2.4 2 8.2 0.2 2.3 2 0 0 2 2 2 0 MukB N-terminal AAA_13 PF13166.6 CDJ88269.1 - 0.2 10.3 0.6 3.5 6.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CDJ88269.1 - 1.4 8.6 3.5 8.8 6.0 0.2 2.7 2 1 1 3 3 3 0 AAA domain AlbA_2 PF04326.14 CDJ88271.1 - 0.00014 22.2 0.0 0.0002 21.6 0.0 1.3 1 0 0 1 1 1 1 Putative DNA-binding domain DUF3269 PF11673.8 CDJ88271.1 - 0.012 15.9 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3269) Clathrin_bdg PF15045.6 CDJ88271.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking WW PF00397.26 CDJ88271.1 - 1.7 8.8 4.6 6.8 6.9 0.2 2.4 2 0 0 2 2 2 0 WW domain BicD PF09730.9 CDJ88272.1 - 1.1e-101 341.5 69.1 1e-58 199.4 23.4 2.8 1 1 2 3 3 3 2 Microtubule-associated protein Bicaudal-D APG6_N PF17675.1 CDJ88272.1 - 0.012 16.1 13.8 0.012 16.1 13.8 7.2 3 2 3 6 6 6 0 Apg6 coiled-coil region BcrAD_BadFG PF01869.20 CDJ88272.1 - 0.69 9.4 3.4 8.5 5.8 0.1 3.3 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family DUF812 PF05667.11 CDJ88272.1 - 2.6 6.8 63.8 0.02 13.8 21.8 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF812) FtsJ PF01728.19 CDJ88273.1 - 8.5e-35 120.4 0.0 1.5e-34 119.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase G-patch PF01585.23 CDJ88273.1 - 1.9e-11 43.7 1.4 1.9e-11 43.7 1.4 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 CDJ88273.1 - 0.0025 17.8 0.5 0.0059 16.7 0.5 1.6 1 0 0 1 1 1 1 G-patch domain ICAT PF06384.11 CDJ88274.1 - 8.2e-10 38.8 0.5 8.2e-10 38.8 0.5 2.1 2 0 0 2 2 2 1 Beta-catenin-interacting protein ICAT DUF1104 PF06518.11 CDJ88274.1 - 0.00032 21.0 6.0 0.054 13.9 0.6 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1104) DMAP_binding PF06464.11 CDJ88274.1 - 0.00097 19.9 5.2 0.011 16.6 0.3 2.3 2 0 0 2 2 2 1 DMAP1-binding Domain FANCI_S4 PF14678.6 CDJ88274.1 - 0.004 16.3 0.4 0.0069 15.5 0.4 1.3 1 0 0 1 1 1 1 FANCI solenoid 4 GvpG PF05120.12 CDJ88274.1 - 0.0046 16.9 9.2 0.013 15.5 0.4 2.2 2 0 0 2 2 2 1 Gas vesicle protein G FlxA PF14282.6 CDJ88274.1 - 0.012 15.6 1.9 0.012 15.6 1.9 2.1 2 1 0 2 2 2 0 FlxA-like protein CAMP_factor PF07373.11 CDJ88274.1 - 0.018 14.7 1.8 0.022 14.4 1.1 1.4 1 1 0 1 1 1 0 CAMP factor (Cfa) DUF2664 PF10867.8 CDJ88274.1 - 0.025 15.0 1.4 0.11 12.9 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2664) TraF_2 PF13729.6 CDJ88274.1 - 0.09 12.1 0.4 0.094 12.1 0.4 1.2 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein Occludin_ELL PF07303.13 CDJ88274.1 - 0.38 11.5 5.2 2.4 9.0 0.4 2.2 2 0 0 2 2 2 0 Occludin homology domain PRP1_N PF06424.12 CDJ88274.1 - 0.98 9.8 5.5 0.56 10.6 0.6 2.1 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DUF883 PF05957.13 CDJ88274.1 - 1.2 9.8 8.6 0.3 11.7 3.3 2.3 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DASH_Hsk3 PF08227.11 CDJ88274.1 - 1.9 8.9 6.0 6.4 7.2 1.9 3.0 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like PGM_PMM_IV PF00408.20 CDJ88275.1 - 3.8e-09 36.6 0.1 7.5e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 CDJ88275.1 - 0.0053 16.9 0.0 0.0092 16.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Metal_hydrol PF10118.9 CDJ88276.1 - 0.041 13.6 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Predicted metal-dependent hydrolase eIF3g PF12353.8 CDJ88276.1 - 0.72 10.3 3.9 0.37 11.2 1.6 1.7 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G RT_RNaseH_2 PF17919.1 CDJ88277.1 - 3.5e-32 110.4 0.0 5.1e-32 109.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ88277.1 - 6e-25 87.6 0.0 8.9e-25 87.0 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ88278.1 - 1e-43 148.3 0.0 4.4e-22 78.5 0.0 2.4 1 1 1 2 2 2 2 Integrase core domain Integrase_H2C2 PF17921.1 CDJ88278.1 - 3.9e-12 46.1 0.1 6.9e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CDJ88278.1 - 3.9e-09 36.2 0.8 0.00092 18.9 0.0 3.4 3 0 0 3 3 3 2 Integrase core domain zf-H2C2 PF09337.10 CDJ88278.1 - 0.0001 22.4 0.0 0.00018 21.7 0.0 1.4 1 0 0 1 1 1 1 H2C2 zinc finger PIG-H PF10181.9 CDJ88278.1 - 0.045 13.6 0.2 0.21 11.4 0.0 2.2 3 0 0 3 3 3 0 GPI-GlcNAc transferase complex, PIG-H component Nepo_coat_N PF03689.15 CDJ88278.1 - 0.047 13.6 0.2 11 6.0 0.0 2.4 2 0 0 2 2 2 0 Nepovirus coat protein, N-terminal domain Peptidase_M50 PF02163.22 CDJ88278.1 - 0.057 12.7 0.0 0.066 12.5 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M50 Phenol_hyd_sub PF06099.11 CDJ88278.1 - 0.1 12.6 1.2 19 5.4 0.1 2.7 2 0 0 2 2 2 0 Phenol hydroxylase subunit gag_pre-integrs PF13976.6 CDJ88278.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 GAG-pre-integrase domain EC042_2821 PF18740.1 CDJ88278.1 - 0.22 11.4 0.0 25 4.7 0.0 2.2 2 0 0 2 2 2 0 EC042_2821-lke REase LIP1 PF15904.5 CDJ88278.1 - 0.36 11.2 1.2 29 5.1 0.1 2.4 2 0 0 2 2 2 0 LKB1 serine/threonine kinase interacting protein 1 PGM_PMM_I PF02878.16 CDJ88279.1 - 7.4e-18 64.6 0.1 7.7e-10 38.6 0.0 2.2 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 CDJ88279.1 - 0.029 15.0 0.4 0.52 11.0 0.2 2.9 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Motile_Sperm PF00635.26 CDJ88280.1 - 0.00018 21.3 0.0 0.00023 21.0 0.0 1.1 1 0 0 1 1 1 1 MSP (Major sperm protein) domain RCR PF12273.8 CDJ88281.1 - 0.0015 19.1 0.1 0.0023 18.6 0.1 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Adeno_E3_CR2 PF02439.15 CDJ88281.1 - 0.033 13.9 0.7 0.048 13.4 0.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 CDJ88281.1 - 0.038 14.9 0.0 0.056 14.3 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.11 CDJ88281.1 - 0.042 13.4 0.5 0.066 12.8 0.5 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF948 PF06103.11 CDJ88281.1 - 0.083 13.2 0.1 0.12 12.7 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF4446 PF14584.6 CDJ88281.1 - 0.11 12.5 0.2 0.14 12.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) WBP-1 PF11669.8 CDJ88281.1 - 0.33 11.6 1.2 1.2 9.8 1.2 1.9 1 1 0 1 1 1 0 WW domain-binding protein 1 adh_short PF00106.25 CDJ88282.1 - 5.1e-20 71.7 0.0 7.1e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ88282.1 - 5.4e-18 65.4 0.0 7e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CAP PF00188.26 CDJ88283.1 - 1.1e-21 77.9 0.0 1.9e-12 48.1 0.0 2.6 2 1 0 2 2 2 2 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ88283.1 - 0.00023 21.5 0.3 0.46 10.8 0.1 2.8 2 1 0 2 2 2 2 Ancylostoma-associated secreted protein related DX PF01666.17 CDJ88283.1 - 0.4 11.2 5.2 0.58 10.7 3.5 2.3 3 0 0 3 3 3 0 DX module Collagen PF01391.18 CDJ88284.1 - 5.6e-24 83.7 83.1 5.4e-10 38.9 31.7 3.5 3 0 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ88284.1 - 3.9e-12 46.0 0.0 6e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain CD20 PF04103.15 CDJ88284.1 - 0.15 12.1 0.1 0.21 11.7 0.1 1.1 1 0 0 1 1 1 0 CD20-like family RVT_1 PF00078.27 CDJ88286.1 - 7.2e-21 74.7 0.0 8.7e-21 74.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Collagen PF01391.18 CDJ88287.1 - 2.8e-24 84.6 90.3 2.8e-10 39.8 34.2 3.7 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ88287.1 - 0.011 15.8 0.2 0.015 15.3 0.2 1.3 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ88288.1 - 1.8e-26 91.6 104.4 3.4e-11 42.7 36.3 3.6 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ88288.1 - 0.05 13.7 0.0 0.063 13.4 0.0 1.1 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ88289.1 - 1.3e-23 82.5 104.1 1.1e-10 41.1 35.4 4.1 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ88289.1 - 6.8e-20 70.9 0.1 9.2e-20 70.5 0.1 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Oleosin PF01277.17 CDJ88289.1 - 0.16 11.7 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Oleosin Pkinase_Tyr PF07714.17 CDJ88290.1 - 4.6e-81 271.9 0.0 5.8e-81 271.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ88290.1 - 8.7e-48 163.0 0.0 1.2e-47 162.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDJ88290.1 - 3.8e-12 46.1 0.0 8.4e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Kdo PF06293.14 CDJ88290.1 - 0.005 16.2 0.1 0.008 15.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDJ88290.1 - 0.035 13.7 0.3 0.083 12.5 0.3 1.6 1 1 0 1 1 1 0 RIO1 family Gal4_dimer PF03902.13 CDJ88290.1 - 0.066 13.4 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Gal4-like dimerisation domain Skp1_POZ PF03931.15 CDJ88290.1 - 0.071 13.3 0.1 0.26 11.5 0.0 1.9 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain Pkinase_fungal PF17667.1 CDJ88290.1 - 0.12 11.1 0.0 0.22 10.3 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase HECW1_helix PF18436.1 CDJ88290.1 - 0.18 12.0 0.3 0.38 10.9 0.3 1.5 1 0 0 1 1 1 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 HCMV_UL139 PF12507.8 CDJ88294.1 - 0.083 13.3 1.8 0.16 12.3 1.7 1.6 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein CorA PF01544.18 CDJ88294.1 - 0.14 11.4 6.9 0.26 10.6 6.3 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF919 PF06034.11 CDJ88294.1 - 4.7 7.1 8.8 1.1 9.1 4.5 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Costars PF14705.6 CDJ88296.1 - 2.8e-26 91.5 0.1 3.7e-26 91.1 0.1 1.2 1 0 0 1 1 1 1 Costars RRM_1 PF00076.22 CDJ88297.1 - 4.7e-18 64.8 0.0 8.5e-18 63.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) STD1 PF17235.2 CDJ88297.1 - 0.024 14.3 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 STD1/MTH1 DUF383 PF04063.14 CDJ88298.1 - 2.3e-19 69.8 0.8 5.8e-19 68.5 0.4 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 CDJ88298.1 - 4.2e-19 68.1 0.1 8.2e-19 67.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) DUF2277 PF10041.9 CDJ88298.1 - 0.0028 17.9 0.0 0.047 14.0 0.0 2.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2277) TAF6_C PF07571.13 CDJ88298.1 - 0.09 13.1 0.8 3 8.2 0.0 3.1 2 1 1 3 3 3 0 TAF6 C-terminal HEAT repeat domain T-box PF00907.22 CDJ88299.1 - 3e-84 281.9 0.2 3.7e-84 281.6 0.2 1.1 1 0 0 1 1 1 1 T-box Sugar_tr PF00083.24 CDJ88300.1 - 6.6e-56 190.1 22.5 8.1e-56 189.8 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ88300.1 - 4.1e-17 62.1 37.9 4.8e-10 38.9 13.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DnaJ PF00226.31 CDJ88302.1 - 7.6e-23 80.4 0.6 7.6e-23 80.4 0.6 2.2 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 CDJ88302.1 - 4.5e-10 39.5 3.4 4.5e-10 39.5 3.4 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CDJ88302.1 - 7e-05 23.1 14.5 0.16 12.3 0.0 3.5 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CDJ88302.1 - 9.8e-05 22.6 2.2 0.0003 21.1 2.2 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CDJ88302.1 - 0.063 13.8 14.0 0.38 11.3 1.5 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ88302.1 - 0.29 12.1 14.5 0.6 11.1 0.9 4.1 5 0 0 5 5 5 0 C2H2-type zinc finger THAP PF05485.12 CDJ88302.1 - 1.2 10.2 5.2 6.9 7.7 5.2 2.5 1 1 0 1 1 1 0 THAP domain DUF1981 PF09324.10 CDJ88303.1 - 0.054 13.4 0.8 0.32 10.9 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) RVT_1 PF00078.27 CDJ88304.1 - 7.7e-13 48.5 0.0 1.4e-12 47.6 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MAD PF05557.13 CDJ88305.1 - 0.012 14.0 0.1 0.021 13.2 0.1 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein ATP-synt_E_2 PF08112.11 CDJ88305.1 - 0.042 14.1 1.0 0.45 10.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase epsilon subunit APG17 PF04108.12 CDJ88305.1 - 0.26 10.3 1.4 0.29 10.2 0.3 1.7 2 1 0 2 2 2 0 Autophagy protein Apg17 Itfg2 PF15907.5 CDJ88307.1 - 0.19 10.7 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Integrin-alpha FG-GAP repeat-containing protein 2 PTEN_C2 PF10409.9 CDJ88308.1 - 5e-07 29.5 0.0 7.7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DnaJ PF00226.31 CDJ88309.1 - 1.4e-06 28.3 0.0 2.9e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Neur_chan_LBD PF02931.23 CDJ88310.1 - 3e-13 49.7 0.2 3.5e-13 49.5 0.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Fn3-like PF14310.6 CDJ88310.1 - 0.0085 16.2 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF1842 PF08896.10 CDJ88310.1 - 0.1 12.9 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1842) Bestrophin PF01062.21 CDJ88311.1 - 5.6e-89 298.4 5.1 6.8e-89 298.1 5.1 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Ribosomal_L18 PF17135.4 CDJ88312.1 - 6.6e-91 302.8 2.1 7.4e-91 302.6 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CDJ88312.1 - 0.046 14.4 0.2 0.15 12.7 0.2 1.9 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A PEHE PF15275.6 CDJ88313.1 - 0.0004 21.0 2.4 0.0004 21.0 2.4 1.8 2 0 0 2 2 2 1 PEHE domain EcsB PF05975.12 CDJ88314.1 - 0.28 10.0 15.9 0.3 9.9 15.9 1.0 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB DUF3792 PF12670.7 CDJ88314.1 - 0.3 11.2 24.3 0.51 10.5 24.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3792) DUF4231 PF14015.6 CDJ88314.1 - 1.3 9.5 15.6 3.8 8.0 3.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) EXS PF03124.14 CDJ88314.1 - 1.9 7.7 10.1 2.4 7.4 10.1 1.0 1 0 0 1 1 1 0 EXS family CPP1-like PF11833.8 CDJ88314.1 - 2.9 7.5 11.5 3.7 7.1 11.5 1.2 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF4637 PF15470.6 CDJ88315.1 - 4.1 7.1 11.9 18 5.0 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) FOXP-CC PF16159.5 CDJ88315.1 - 8 7.2 7.5 14 6.4 0.1 3.2 3 0 0 3 3 3 0 FOXP coiled-coil domain ThiF PF00899.21 CDJ88316.1 - 1.9e-68 230.4 0.0 2.5e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 CDJ88316.1 - 1.5e-09 37.9 0.3 2.5e-09 37.2 0.3 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 CDJ88316.1 - 0.018 15.1 0.0 0.043 13.9 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UBA_e1_thiolCys PF10585.9 CDJ88316.1 - 0.2 11.5 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-activating enzyme active site DUF35_N PF12172.8 CDJ88316.1 - 0.49 10.3 2.3 5.8 6.9 0.8 2.5 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Rep_fac-A_C PF08646.10 CDJ88317.1 - 1e-44 151.8 2.5 2.8e-44 150.4 1.2 2.1 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 CDJ88317.1 - 7.4e-24 83.5 0.2 2e-20 72.5 0.0 2.7 3 0 0 3 3 3 2 Replication protein A OB domain tRNA_anti-codon PF01336.25 CDJ88317.1 - 2.9e-11 43.2 0.0 3.2e-05 23.8 0.0 3.4 3 0 0 3 3 3 3 OB-fold nucleic acid binding domain GDNF PF02351.16 CDJ88318.1 - 0.0039 18.1 14.9 0.0039 18.1 14.9 2.6 2 0 0 2 2 2 2 GDNF/GAS1 domain EamA PF00892.20 CDJ88319.1 - 3.3e-06 27.3 14.1 3.3e-06 27.3 14.1 2.4 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 CDJ88319.1 - 4.5e-05 22.8 8.9 4.5e-05 22.8 8.9 1.8 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport TPT PF03151.16 CDJ88319.1 - 0.00089 18.7 12.0 0.00089 18.7 12.0 1.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family Peptidase_M14 PF00246.24 CDJ88320.1 - 3.8e-72 243.5 0.0 4.9e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 CDJ88320.1 - 4.8e-13 49.2 0.5 1.3e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 CDJ88320.1 - 9e-06 25.6 0.0 2.6e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 CarboxypepD_reg-like domain PEGA PF08308.11 CDJ88320.1 - 0.0016 18.3 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 PEGA domain AstE_AspA PF04952.14 CDJ88320.1 - 0.016 14.3 0.0 0.043 12.9 0.0 1.7 1 1 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Vitellogenin_N PF01347.22 CDJ88321.1 - 5.4e-81 272.8 16.5 6.5e-55 186.7 0.9 2.8 2 1 1 3 3 3 2 Lipoprotein amino terminal region DUF1943 PF09172.11 CDJ88321.1 - 2.1e-35 122.5 0.1 5.2e-35 121.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) VWD PF00094.25 CDJ88321.1 - 2.6e-18 66.8 0.1 7.1e-18 65.4 0.1 1.8 1 0 0 1 1 1 1 von Willebrand factor type D domain Pox_A22 PF04848.13 CDJ88321.1 - 0.0042 17.2 0.7 0.027 14.6 0.0 2.6 2 0 0 2 2 2 1 Poxvirus A22 protein UBA_6 PF18039.1 CDJ88321.1 - 0.027 14.4 0.2 0.079 12.9 0.2 1.7 1 0 0 1 1 1 0 UBA-like domain Spo0A_C PF08769.11 CDJ88321.1 - 0.8 9.8 6.4 0.22 11.6 0.2 2.8 3 0 0 3 3 3 0 Sporulation initiation factor Spo0A C terminal FAM176 PF14851.6 CDJ88322.1 - 0.0048 16.6 2.4 0.01 15.5 2.4 1.6 1 1 0 1 1 1 1 FAM176 family GTSE1_N PF15259.6 CDJ88322.1 - 0.12 12.5 5.5 0.17 12.1 5.5 1.1 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 Ndc1_Nup PF09531.10 CDJ88322.1 - 0.23 10.1 1.9 0.25 10.0 1.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DOCK_N PF16172.5 CDJ88323.1 - 2.3e-31 109.1 0.5 3.3e-31 108.5 0.5 1.1 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 CDJ88323.1 - 2.5e-15 56.8 0.1 7.6e-15 55.2 0.0 1.8 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins SH3_2 PF07653.17 CDJ88323.1 - 0.033 13.9 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain Collagen PF01391.18 CDJ88324.1 - 9.3e-25 86.2 112.5 2.8e-10 39.8 41.1 3.8 2 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ88324.1 - 1.8e-14 53.5 0.2 2.3e-14 53.2 0.2 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain SCVP PF17619.2 CDJ88325.1 - 5.4e-41 139.4 1.5 1.5e-23 83.5 1.0 2.2 2 0 0 2 2 2 2 Secreted clade V proteins CAF1A PF12253.8 CDJ88325.1 - 0.026 14.7 0.1 0.068 13.3 0.0 1.7 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A SCVP PF17619.2 CDJ88326.1 - 1.5e-62 208.5 7.9 1.7e-24 86.5 0.3 3.1 3 0 0 3 3 3 3 Secreted clade V proteins DUF866 PF05907.13 CDJ88326.1 - 0.034 14.1 0.8 0.61 10.0 0.1 2.7 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF866) SCVP PF17619.2 CDJ88327.1 - 4.5e-11 43.5 0.0 6.4e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Secreted clade V proteins SCVP PF17619.2 CDJ88328.1 - 2.8e-16 60.1 0.0 3.8e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Secreted clade V proteins SCVP PF17619.2 CDJ88329.1 - 2.2e-07 31.6 0.1 2.7e-07 31.3 0.1 1.3 1 1 0 1 1 1 1 Secreted clade V proteins RVT_1 PF00078.27 CDJ88329.1 - 0.091 12.3 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ion_trans_2 PF07885.16 CDJ88330.1 - 1.6e-34 117.7 10.1 7.7e-18 64.2 0.9 2.2 2 0 0 2 2 2 2 Ion channel HTH_Tnp_Tc3_2 PF01498.18 CDJ88331.1 - 1.8e-22 79.3 0.7 1.8e-22 79.3 0.7 1.9 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 CDJ88331.1 - 1.4e-08 35.2 6.0 4.7e-08 33.5 0.8 2.4 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 CDJ88331.1 - 6.5e-05 22.6 2.1 0.0043 16.8 0.1 2.7 2 1 0 2 2 2 1 Homeodomain-like domain PAX PF00292.18 CDJ88331.1 - 0.0002 21.3 0.2 0.00029 20.7 0.2 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_24 PF13412.6 CDJ88331.1 - 0.00075 19.0 3.2 0.71 9.5 0.8 3.3 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 CDJ88331.1 - 0.0047 16.8 3.3 0.41 10.6 0.5 2.5 2 1 0 2 2 2 2 MarR family HTH_28 PF13518.6 CDJ88331.1 - 0.0062 16.6 0.4 0.59 10.3 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 CDJ88331.1 - 0.0082 15.8 4.5 0.81 9.4 0.1 3.5 3 1 0 3 3 3 1 Sigma-70, region 4 HTH_29 PF13551.6 CDJ88331.1 - 0.0097 15.9 1.3 0.22 11.6 0.4 2.5 2 0 0 2 2 2 1 Winged helix-turn helix Sigma70_r4 PF04545.16 CDJ88331.1 - 0.011 15.3 0.5 1.4 8.5 0.2 2.8 2 1 0 2 2 2 0 Sigma-70, region 4 HTH_12 PF08461.10 CDJ88331.1 - 0.014 15.4 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain CENP-B_N PF04218.13 CDJ88331.1 - 0.028 14.0 0.2 9.3 6.0 0.1 2.3 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain TrmB PF01978.19 CDJ88331.1 - 0.067 13.1 0.0 0.86 9.5 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB GerE PF00196.19 CDJ88331.1 - 0.25 10.9 0.7 5.5 6.6 0.0 2.8 3 1 0 3 3 3 0 Bacterial regulatory proteins, luxR family HTH_Crp_2 PF13545.6 CDJ88331.1 - 0.5 10.4 3.0 0.88 9.6 0.2 2.4 2 1 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_AsnC-type PF13404.6 CDJ88331.1 - 1.9 8.4 5.2 4 7.4 2.1 2.7 2 1 0 2 2 2 0 AsnC-type helix-turn-helix domain PWI PF01480.17 CDJ88332.1 - 5.2e-14 52.3 0.2 1.3e-13 51.1 0.2 1.7 1 0 0 1 1 1 1 PWI domain ACPS PF01648.20 CDJ88333.1 - 1.3e-18 67.2 0.0 2.8e-17 62.9 0.0 2.2 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Pro_isomerase PF00160.21 CDJ88334.1 - 1.2e-10 41.8 0.0 1.5e-10 41.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DSL PF01414.19 CDJ88335.1 - 7.2e-11 42.2 2.0 1.4e-10 41.3 2.0 1.4 1 0 0 1 1 1 1 Delta serrate ligand DUF2177 PF09945.9 CDJ88335.1 - 0.0076 16.3 0.1 0.014 15.5 0.1 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2177) Bax1-I PF01027.20 CDJ88336.1 - 7e-21 75.0 45.3 8.1e-21 74.8 45.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 ART PF01129.18 CDJ88336.1 - 0.098 11.9 0.2 13 5.0 0.1 2.1 2 0 0 2 2 2 0 NAD:arginine ADP-ribosyltransferase Homeodomain PF00046.29 CDJ88337.1 - 2.5e-20 72.1 4.8 3.5e-20 71.6 4.8 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ88337.1 - 0.0082 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2 PF00096.26 CDJ88338.1 - 3.3e-14 52.5 30.2 0.00021 21.5 0.6 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ88338.1 - 7e-14 51.5 25.9 8.9e-07 29.1 8.7 4.4 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDJ88338.1 - 1.2e-08 35.1 28.3 0.00028 21.5 1.0 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-TRAF PF02176.18 CDJ88338.1 - 0.0041 17.8 3.1 0.0041 17.8 3.1 2.9 1 1 2 3 3 3 1 TRAF-type zinc finger zf-C2H2_8 PF15909.5 CDJ88338.1 - 0.036 14.4 11.5 0.17 12.2 0.9 2.5 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2HE PF16278.5 CDJ88338.1 - 0.063 13.7 0.3 0.063 13.7 0.3 2.9 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 CDJ88338.1 - 0.086 12.6 0.7 0.086 12.6 0.7 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 CDJ88338.1 - 0.1 12.4 0.3 0.1 12.4 0.3 4.5 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zinc_ribbon_15 PF17032.5 CDJ88338.1 - 0.47 11.3 6.3 2.7 8.8 1.0 2.4 1 1 0 2 2 2 0 zinc-ribbon family Rpr2 PF04032.16 CDJ88338.1 - 0.92 9.8 5.8 1.1 9.5 0.4 2.5 1 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain WD40 PF00400.32 CDJ88339.1 - 7.7e-44 146.8 34.9 2.5e-07 31.3 0.2 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ88339.1 - 4.9e-13 49.2 3.4 0.12 12.7 0.1 5.7 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 CDJ88339.1 - 1.2e-10 41.1 0.5 2.8e-10 39.9 0.5 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 CDJ88339.1 - 1.8e-09 36.8 12.5 0.091 11.4 0.2 6.6 3 2 4 7 7 7 4 Nucleoporin Nup120/160 F-box PF00646.33 CDJ88339.1 - 2.3e-09 36.9 0.4 2.3e-09 36.9 0.4 2.0 2 0 0 2 2 2 1 F-box domain WD40_like PF17005.5 CDJ88339.1 - 0.018 14.4 0.9 3.7 6.8 0.0 3.4 2 1 3 5 5 5 0 WD40-like domain PALB2_WD40 PF16756.5 CDJ88339.1 - 0.039 12.9 6.9 19 4.0 0.2 4.7 1 1 3 5 5 5 0 Partner and localizer of BRCA2 WD40 domain F-box_4 PF15966.5 CDJ88339.1 - 0.077 12.9 0.0 0.28 11.1 0.0 2.0 1 0 0 1 1 1 0 F-box Nucleoporin_N PF08801.11 CDJ88339.1 - 0.21 10.3 3.7 3.3 6.4 0.1 3.5 2 1 1 4 4 4 0 Nup133 N terminal like tRNA_U5-meth_tr PF05958.11 CDJ88339.1 - 0.23 10.4 0.0 0.35 9.8 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase PolyA_pol PF01743.20 CDJ88340.1 - 1.8e-35 122.2 0.8 2.8e-35 121.5 0.8 1.3 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 CDJ88340.1 - 1.4e-07 31.1 0.0 4.6e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A Mtf2_C PF14061.6 CDJ88340.1 - 0.095 12.9 0.0 9.4 6.5 0.0 2.6 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 MFS_1 PF07690.16 CDJ88341.1 - 3e-10 39.6 8.4 2.3e-08 33.4 3.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_cobalt PF09819.9 CDJ88341.1 - 0.024 14.8 0.2 0.024 14.8 0.2 2.3 2 2 0 2 2 2 0 ABC-type cobalt transport system, permease component MerC PF03203.14 CDJ88341.1 - 0.044 14.2 0.3 0.044 14.2 0.3 2.2 1 1 1 2 2 2 0 MerC mercury resistance protein DUF2119 PF09892.9 CDJ88343.1 - 0.049 13.0 0.1 0.052 12.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) Latrotoxin_C PF15658.6 CDJ88344.1 - 1.3 8.8 4.9 32 4.3 0.1 3.4 2 2 2 4 4 4 0 Latrotoxin C-terminal domain Astacin PF01400.24 CDJ88345.1 - 1.6e-69 233.4 0.0 2.6e-69 232.7 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB PF00431.20 CDJ88345.1 - 4.8e-05 23.7 0.3 8.1e-05 22.9 0.3 1.3 1 0 0 1 1 1 1 CUB domain Reprolysin_4 PF13583.6 CDJ88345.1 - 0.018 14.7 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CDJ88345.1 - 0.072 12.9 0.9 0.9 9.4 0.4 2.1 1 1 0 2 2 2 0 Matrixin Reprolysin_3 PF13582.6 CDJ88345.1 - 0.16 12.5 0.3 0.36 11.4 0.3 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 CDJ88345.1 - 0.18 10.4 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Asp PF00026.23 CDJ88347.1 - 1.6e-20 73.8 0.0 2.3e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ88347.1 - 5.8e-09 36.4 0.2 8.1e-09 36.0 0.2 1.2 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal DNA_Packaging PF11053.8 CDJ88348.1 - 0.076 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Terminase DNA packaging enzyme rve PF00665.26 CDJ88349.1 - 6e-08 32.9 0.0 7.4e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain Pkinase_Tyr PF07714.17 CDJ88351.1 - 6.9e-77 258.2 0.0 9.6e-77 257.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ88351.1 - 3.1e-43 148.1 0.0 4.8e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDJ88351.1 - 1.1e-08 35.1 0.0 2.2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 SH2 domain Kinase-like PF14531.6 CDJ88351.1 - 0.0072 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDJ88351.1 - 0.03 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Linker_histone PF00538.19 CDJ88354.1 - 2.1e-27 95.3 0.6 2.1e-27 95.3 0.6 2.0 2 0 0 2 2 2 1 linker histone H1 and H5 family Sulfolobus_pRN PF05584.11 CDJ88354.1 - 0.084 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Sulfolobus plasmid regulatory protein C6 PF01681.17 CDJ88355.1 - 9.1e-07 29.3 0.5 1.2e-06 28.9 0.5 1.2 1 0 0 1 1 1 1 C6 domain C6 PF01681.17 CDJ88356.1 - 0.005 17.3 0.5 0.008 16.7 0.4 1.4 1 1 0 1 1 1 1 C6 domain HTH_48 PF17906.1 CDJ88357.1 - 0.00013 22.0 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 HTH domain in Mos1 transposase Ras PF00071.22 CDJ88358.1 - 1.3e-50 171.2 1.5 1.3e-50 171.2 0.2 1.6 2 0 0 2 2 2 1 Ras family Roc PF08477.13 CDJ88358.1 - 2e-32 111.9 0.1 5.5e-32 110.5 0.1 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ88358.1 - 2.7e-16 59.5 0.0 5e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ88358.1 - 4.9e-07 29.3 0.4 8.4e-07 28.6 0.0 1.6 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDJ88358.1 - 2.6e-06 27.5 0.2 6.8e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ88358.1 - 5.2e-06 26.1 0.1 3.3e-05 23.5 0.0 2.2 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain EF-hand_7 PF13499.6 CDJ88358.1 - 0.0013 19.1 1.0 0.0041 17.5 1.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ88358.1 - 0.0025 17.6 3.4 0.012 15.5 0.3 3.0 3 0 0 3 3 3 1 EF-hand domain RST PF12174.8 CDJ88358.1 - 0.0064 16.4 0.3 0.016 15.1 0.3 1.7 1 0 0 1 1 1 1 RCD1-SRO-TAF4 (RST) plant domain EF-hand_1 PF00036.32 CDJ88358.1 - 0.01 15.3 1.8 0.046 13.3 0.4 2.6 2 0 0 2 2 2 0 EF hand SRPRB PF09439.10 CDJ88358.1 - 0.036 13.5 0.0 0.085 12.3 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MCPVI PF02993.14 CDJ88358.1 - 0.56 10.0 5.0 4.8 7.0 0.4 2.3 1 1 1 2 2 2 0 Minor capsid protein VI Comm PF15957.5 CDJ88359.1 - 0.026 14.8 0.3 0.052 13.9 0.0 1.6 1 1 1 2 2 2 0 Commissureless HSP70 PF00012.20 CDJ88360.1 - 6.4e-266 883.3 7.6 7.3e-266 883.1 7.6 1.0 1 0 0 1 1 1 1 Hsp70 protein L_HMGIC_fpl PF10242.9 CDJ88360.1 - 3.1e-27 95.9 4.2 4.9e-27 95.3 4.2 1.2 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein MreB_Mbl PF06723.13 CDJ88360.1 - 1e-16 60.7 0.1 4.7e-15 55.2 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CDJ88360.1 - 0.00093 19.0 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 CDJ88360.1 - 0.0051 17.2 0.6 10 6.6 0.0 3.4 3 0 0 3 3 3 1 Cell division protein FtsA BcrAD_BadFG PF01869.20 CDJ88360.1 - 0.017 14.6 0.1 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DUF1464 PF07318.12 CDJ88360.1 - 0.085 12.0 0.1 0.2 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1464) Hydantoinase_A PF01968.18 CDJ88360.1 - 0.1 11.8 1.0 0.21 10.8 0.2 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase HORMA PF02301.18 CDJ88360.1 - 0.25 10.9 1.5 0.62 9.6 1.5 1.7 1 0 0 1 1 1 0 HORMA domain RD3 PF14473.6 CDJ88360.1 - 1.2 9.0 7.9 3.1 7.6 3.3 2.6 1 1 1 2 2 2 0 RD3 protein Methyltransf_21 PF05050.12 CDJ88361.1 - 2e-13 50.7 0.1 2.2e-13 50.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain LSM PF01423.22 CDJ88362.1 - 3.5e-13 49.0 0.3 5e-13 48.5 0.3 1.2 1 0 0 1 1 1 1 LSM domain ADH_N PF08240.12 CDJ88362.1 - 0.059 13.3 0.1 0.076 12.9 0.1 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DNA_pol3_tau_5 PF12170.8 CDJ88362.1 - 0.19 11.8 0.0 0.25 11.4 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase III tau subunit V interacting with alpha PXA PF02194.15 CDJ88363.1 - 3e-47 160.9 1.6 4.3e-46 157.2 0.5 2.3 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 CDJ88363.1 - 2.3e-25 89.3 0.5 1.8e-24 86.5 0.1 2.5 2 0 0 2 2 2 1 Sorting nexin C terminal RGS PF00615.19 CDJ88363.1 - 3.2e-16 59.7 1.9 7.2e-16 58.5 0.0 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain PX PF00787.24 CDJ88363.1 - 2.1e-14 53.4 0.0 4.6e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 PX domain Fructosamin_kin PF03881.14 CDJ88364.1 - 6.9e-70 235.5 0.0 1.5e-69 234.4 0.0 1.5 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.23 CDJ88364.1 - 7.5e-07 29.3 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CDJ88364.1 - 0.00067 19.3 0.0 0.0061 16.2 0.0 2.0 2 0 0 2 2 2 1 RIO1 family MFS_5 PF05631.14 CDJ88365.1 - 1.6e-19 70.1 3.6 2e-19 69.8 3.6 1.0 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 CDJ88365.1 - 7e-09 35.1 10.3 2.8e-08 33.1 8.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ88365.1 - 0.0026 16.7 5.2 0.0064 15.4 2.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 CDJ88365.1 - 0.026 13.1 6.3 0.035 12.7 6.2 1.3 1 1 0 1 1 1 0 MFS/sugar transport protein DUF4133 PF13571.6 CDJ88365.1 - 0.029 14.7 1.0 0.029 14.7 1.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4133) Itfg2 PF15907.5 CDJ88366.1 - 2.4e-16 59.7 0.1 5.8e-16 58.4 0.0 1.7 2 1 0 2 2 2 1 Integrin-alpha FG-GAP repeat-containing protein 2 VCBS PF13517.6 CDJ88366.1 - 0.042 14.4 0.0 0.26 11.9 0.0 2.3 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 CDJ88366.1 - 0.093 12.9 0.1 0.39 10.9 0.1 2.1 1 0 0 1 1 1 0 FG-GAP repeat BBS2_Mid PF14783.6 CDJ88366.1 - 0.1 12.7 0.0 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Fcf1 PF04900.12 CDJ88367.1 - 1.5e-24 86.3 0.0 4.2e-24 84.8 0.0 1.7 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 CDJ88367.1 - 0.00023 21.4 0.0 0.00086 19.6 0.0 2.1 1 1 0 1 1 1 1 PIN like domain Peroxin-3 PF04882.12 CDJ88368.1 - 4.2e-15 55.7 4.9 9.5e-07 28.2 0.3 3.2 2 2 1 3 3 3 3 Peroxin-3 zf-PHD-like PF15446.6 CDJ88368.1 - 0.16 11.6 0.2 0.44 10.1 0.0 1.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain RRM_5 PF13893.6 CDJ88369.1 - 2e-39 134.0 0.0 5.1e-34 116.6 0.0 3.2 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CDJ88369.1 - 4.2e-24 84.2 0.1 3.4e-07 30.0 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 CDJ88369.1 - 9.7e-12 44.9 0.1 2.1e-11 43.9 0.1 1.5 1 0 0 1 1 1 1 RRM-like domain RRM_3 PF08777.11 CDJ88369.1 - 0.00042 20.3 0.0 0.5 10.4 0.0 3.6 4 0 0 4 4 4 1 RNA binding motif RRM_occluded PF16842.5 CDJ88369.1 - 0.0045 16.8 1.4 0.89 9.5 0.1 3.4 4 0 0 4 4 4 1 Occluded RNA-recognition motif DUF4523 PF15023.6 CDJ88369.1 - 0.0084 15.9 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) RL PF17797.1 CDJ88369.1 - 0.084 12.8 0.0 15 5.6 0.0 3.3 3 0 0 3 3 3 0 RL domain Mito_carr PF00153.27 CDJ88370.1 - 6.2e-65 215.2 1.1 2.2e-23 82.0 0.1 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein Nas2_N PF18265.1 CDJ88370.1 - 1.1e-27 95.7 0.5 1.9e-27 95.0 0.5 1.4 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 CDJ88370.1 - 2.2e-06 27.4 0.0 6e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 CDJ88370.1 - 2.4e-05 24.6 0.0 4.4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CDJ88370.1 - 0.00071 19.9 0.0 0.0012 19.2 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Serine_protease PF18405.1 CDJ88370.1 - 0.024 13.8 0.0 0.57 9.3 0.0 2.7 2 1 0 2 2 2 0 Gammaproteobacterial serine protease Transthyretin PF00576.21 CDJ88371.1 - 6.8e-35 120.1 0.1 7.8e-35 119.9 0.1 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family Comm PF15957.5 CDJ88372.1 - 0.013 15.9 0.0 7.2 7.0 0.0 2.5 2 0 0 2 2 2 0 Commissureless ABC2_membrane_3 PF12698.7 CDJ88372.1 - 0.014 14.5 8.6 0.02 14.0 8.6 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DHHC PF01529.20 CDJ88372.1 - 0.53 10.4 7.0 6.8 6.8 2.8 2.2 1 1 1 2 2 2 0 DHHC palmitoyltransferase PLAC8 PF04749.17 CDJ88372.1 - 0.58 11.2 2.2 0.57 11.2 0.4 1.8 1 1 1 2 2 2 0 PLAC8 family DUF2070 PF09843.9 CDJ88372.1 - 2.3 6.4 5.2 2.6 6.2 5.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TPR_1 PF00515.28 CDJ88374.1 - 8e-20 69.8 13.9 0.00033 20.3 0.0 8.0 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ88374.1 - 4.9e-16 57.5 21.2 0.0039 17.2 1.0 9.3 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ88374.1 - 8.4e-15 54.8 10.9 0.00026 21.2 0.3 5.6 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ88374.1 - 2.5e-13 49.5 0.0 0.034 13.8 0.0 5.7 7 0 0 7 7 7 4 TPR repeat TPR_19 PF14559.6 CDJ88374.1 - 2.6e-12 47.0 15.2 0.00021 21.7 0.3 6.5 4 2 2 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ88374.1 - 2.3e-11 43.0 17.0 0.0026 17.8 0.4 7.6 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ88374.1 - 2.6e-11 43.1 8.3 0.71 10.4 0.0 9.4 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ88374.1 - 4.8e-10 39.9 0.9 1.6e-05 25.4 0.0 4.3 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ88374.1 - 2.8e-09 37.0 11.3 0.16 12.8 0.0 7.0 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ88374.1 - 3.3e-06 26.8 14.0 0.073 13.1 0.2 6.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ88374.1 - 1.3e-05 24.9 8.1 0.12 12.3 1.3 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ88374.1 - 8.9e-05 22.9 13.6 0.34 11.6 0.1 6.9 8 0 0 8 8 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ88374.1 - 0.00019 21.6 6.0 0.0011 19.2 0.4 3.8 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 CDJ88374.1 - 0.00024 21.1 1.0 0.19 11.9 0.0 3.8 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat ANAPC5 PF12862.7 CDJ88374.1 - 0.00057 19.9 1.2 0.28 11.3 0.1 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 5 SRP_TPR_like PF17004.5 CDJ88374.1 - 0.72 9.9 6.2 0.3 11.1 0.7 3.0 3 1 0 3 3 3 0 Putative TPR-like repeat Sod_Cu PF00080.20 CDJ88375.1 - 1.8e-44 151.4 3.9 1.8e-44 151.4 3.9 1.6 1 1 1 2 2 2 1 Copper/zinc superoxide dismutase (SODC) CutC PF03932.14 CDJ88376.1 - 4.1e-60 202.7 0.0 5.2e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 CutC family TBP-binding PF09247.11 CDJ88376.1 - 0.008 16.4 0.0 0.021 15.0 0.0 1.8 1 0 0 1 1 1 1 TATA box-binding protein binding CRAL_TRIO PF00650.20 CDJ88378.1 - 2.1e-20 73.1 0.0 2.8e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CDJ88378.1 - 0.019 15.2 0.0 0.039 14.1 0.0 1.6 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain GnsAB_toxin PF08178.11 CDJ88378.1 - 0.13 12.2 0.2 0.58 10.1 0.1 2.1 2 0 0 2 2 2 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system MIOX PF05153.15 CDJ88379.1 - 2.6e-110 367.9 4.8 2.9e-110 367.7 4.8 1.0 1 0 0 1 1 1 1 Myo-inositol oxygenase PP1_inhibitor PF05361.12 CDJ88380.1 - 1.5e-10 41.3 0.2 1.7e-10 41.1 0.2 1.1 1 0 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor PA28_beta PF02252.18 CDJ88380.1 - 0.0039 16.9 0.0 0.0048 16.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit LRR_4 PF12799.7 CDJ88382.1 - 3e-06 27.5 18.0 1 9.9 2.0 7.2 4 3 1 7 7 7 4 Leucine Rich repeats (2 copies) F-box PF00646.33 CDJ88382.1 - 0.0063 16.4 2.2 0.068 13.1 0.1 3.3 3 0 0 3 3 3 1 F-box domain LRR_8 PF13855.6 CDJ88382.1 - 0.018 14.8 15.8 0.21 11.3 2.2 4.9 5 0 0 5 5 5 0 Leucine rich repeat F-box-like PF12937.7 CDJ88382.1 - 0.019 14.8 0.2 0.019 14.8 0.2 2.7 3 0 0 3 3 3 0 F-box-like LRR_5 PF13306.6 CDJ88382.1 - 0.052 13.5 3.3 0.092 12.7 0.6 2.6 2 1 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 CDJ88382.1 - 1.3 9.9 17.9 7.4 7.5 0.7 6.6 8 1 0 8 8 8 0 Leucine Rich Repeat ACBP PF00887.19 CDJ88384.1 - 0.0012 19.1 0.0 0.0017 18.5 0.0 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein Cys_rich_CPCC PF14206.6 CDJ88384.1 - 0.092 12.6 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Cysteine-rich CPCC DUF1759 PF03564.15 CDJ88385.1 - 4.9e-16 59.0 0.7 7.5e-16 58.4 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) Sigma70_r3 PF04539.16 CDJ88385.1 - 0.041 14.0 0.1 0.13 12.4 0.1 1.8 1 0 0 1 1 1 0 Sigma-70 region 3 Tubulin_C PF03953.17 CDJ88386.1 - 2.1e-50 170.1 0.0 3.7e-50 169.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 CDJ88386.1 - 1e-48 166.1 0.0 1.5e-48 165.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 CDJ88386.1 - 0.00086 19.0 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain DUF4201 PF13870.6 CDJ88387.1 - 0.088 12.5 5.4 1.9 8.2 1.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Wbp11 PF09429.10 CDJ88387.1 - 0.13 12.7 2.3 0.19 12.1 2.3 1.3 1 0 0 1 1 1 0 WW domain binding protein 11 AhpC-TSA_2 PF13911.6 CDJ88388.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.6 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme ArfGap PF01412.18 CDJ88390.1 - 9.2e-43 145.0 0.6 1.4e-42 144.4 0.6 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf NDC10_II PF16787.5 CDJ88390.1 - 0.014 14.4 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 MOZ_SAS PF01853.18 CDJ88391.1 - 9.3e-66 220.9 0.0 1.7e-65 220.0 0.0 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CDJ88391.1 - 6.6e-21 73.7 2.6 1.5e-20 72.6 2.6 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 CDJ88391.1 - 0.00038 20.3 0.6 0.0016 18.3 0.1 2.3 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain SR-25 PF10500.9 CDJ88391.1 - 0.00067 19.3 20.6 0.00067 19.3 20.6 2.6 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein IF2_N PF04760.15 CDJ88391.1 - 0.0035 17.1 0.0 0.0098 15.7 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Dehydrin PF00257.19 CDJ88391.1 - 0.0072 16.9 5.7 0.0072 16.9 5.7 2.1 2 0 0 2 2 2 1 Dehydrin Acetyltransf_7 PF13508.7 CDJ88391.1 - 0.026 15.0 0.0 0.057 13.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDJ88391.1 - 0.081 13.2 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family CDC45 PF02724.14 CDJ88391.1 - 0.085 11.1 15.8 0.18 10.0 15.8 1.6 1 0 0 1 1 1 0 CDC45-like protein UBA_2 PF08587.11 CDJ88391.1 - 0.14 12.3 0.2 20 5.4 0.0 3.2 4 0 0 4 4 4 0 Ubiquitin associated domain (UBA) FR47 PF08445.10 CDJ88391.1 - 0.17 11.9 0.0 0.44 10.5 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Glyco_hydro_15 PF00723.21 CDJ88392.1 - 3.2e-125 418.4 0.0 4.4e-125 418.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 bZIP_2 PF07716.15 CDJ88393.1 - 1.9e-07 31.0 12.8 3.4e-07 30.2 12.8 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CDJ88393.1 - 0.00089 19.7 7.6 0.0016 19.0 7.6 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 CDJ88393.1 - 0.0032 17.5 11.9 0.0052 16.9 11.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor Rft-1 PF04506.13 CDJ88394.1 - 3.9e-99 332.7 37.6 4.7e-99 332.5 37.6 1.0 1 0 0 1 1 1 1 Rft protein CytochromB561_N PF09786.9 CDJ88394.1 - 7 5.5 8.3 0.11 11.5 0.5 1.9 2 0 0 2 2 2 0 Cytochrome B561, N terminal Arf PF00025.21 CDJ88395.1 - 9.9e-63 210.7 0.0 1.1e-62 210.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CDJ88395.1 - 1.6e-10 40.7 0.0 1e-07 31.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CDJ88395.1 - 7e-08 32.1 0.0 9.5e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 CDJ88395.1 - 1.6e-07 31.6 0.0 3.8e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CDJ88395.1 - 4e-07 30.1 0.0 5.5e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 CDJ88395.1 - 6.2e-05 22.7 0.0 6.9e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CDJ88395.1 - 6.4e-05 22.4 0.0 7.2e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.19 CDJ88395.1 - 0.0013 18.4 0.0 0.063 12.9 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AhpC-TSA PF00578.21 CDJ88396.1 - 5.5e-24 84.5 0.0 8e-24 83.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDJ88396.1 - 1.8e-12 47.2 0.0 2.2e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CDJ88396.1 - 0.00078 19.2 0.1 0.0019 18.0 0.1 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.6 CDJ88396.1 - 0.0023 18.0 0.0 0.0064 16.6 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Thioredoxin_8 PF13905.6 CDJ88396.1 - 0.14 12.5 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Metal_resist PF13801.6 CDJ88397.1 - 8e-06 26.1 1.3 0.022 15.0 0.0 3.7 4 0 0 4 4 4 1 Heavy-metal resistance DUF148 PF02520.17 CDJ88397.1 - 2.6e-05 24.3 7.8 3.4e-05 23.9 6.9 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF148 KMP11 PF03037.16 CDJ88397.1 - 0.023 15.5 1.8 0.023 15.5 1.8 2.3 1 1 1 2 2 2 0 Kinetoplastid membrane protein 11 Mer2 PF09074.10 CDJ88397.1 - 0.12 12.2 3.9 0.31 10.8 3.9 1.6 1 1 0 1 1 1 0 Mer2 HEPN-like_int PF18867.1 CDJ88397.1 - 0.19 11.6 1.9 0.37 10.7 1.5 1.7 1 1 0 1 1 1 0 HEPN-like integron domain ING PF12998.7 CDJ88397.1 - 0.2 12.3 4.4 13 6.5 4.3 2.4 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding APG6_N PF17675.1 CDJ88397.1 - 0.5 10.9 7.1 1 9.9 6.8 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region LMBR1 PF04791.16 CDJ88397.1 - 0.71 8.7 2.8 1.1 8.1 2.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein HMG_box_2 PF09011.10 CDJ88397.1 - 1.2 9.8 4.6 0.51 11.0 0.8 2.3 2 1 0 2 2 2 0 HMG-box domain 7TM_GPCR_Srv PF10323.9 CDJ88399.1 - 5.5e-23 81.7 23.0 6.3e-23 81.5 23.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Srg PF02118.21 CDJ88399.1 - 6.1e-15 55.6 26.5 8.3e-15 55.2 26.5 1.1 1 0 0 1 1 1 1 Srg family chemoreceptor 7TM_GPCR_Srx PF10328.9 CDJ88399.1 - 3e-11 43.4 25.3 3.9e-11 43.1 25.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Sru PF10322.9 CDJ88399.1 - 3.1e-05 23.5 12.4 3.1e-05 23.5 12.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sru 7tm_1 PF00001.21 CDJ88399.1 - 0.0052 16.1 19.3 0.0083 15.5 19.2 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PSI_PSAK PF01241.18 CDJ88399.1 - 0.044 13.8 2.6 0.39 10.8 2.6 2.3 1 1 0 1 1 1 0 Photosystem I psaG / psaK DUF998 PF06197.13 CDJ88399.1 - 4.8 6.7 9.4 0.72 9.4 4.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF998) 7TM_GPCR_Srv PF10323.9 CDJ88400.1 - 0.0019 17.6 0.6 0.0021 17.5 0.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv RVT_1 PF00078.27 CDJ88401.1 - 7.6e-27 94.3 0.0 1.6e-26 93.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7TM_GPCR_Srv PF10323.9 CDJ88403.1 - 2.3e-16 60.0 9.7 3.5e-16 59.4 9.7 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 CDJ88403.1 - 7.9e-11 42.1 13.5 1e-10 41.7 13.5 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Srg PF02118.21 CDJ88403.1 - 4.8e-08 33.0 15.2 1.3e-07 31.5 15.2 1.6 1 1 0 1 1 1 1 Srg family chemoreceptor 7tm_1 PF00001.21 CDJ88403.1 - 0.0011 18.4 8.9 0.0014 18.0 8.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srt PF10321.9 CDJ88403.1 - 0.0086 15.1 11.7 0.014 14.4 11.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt Serpentine_r_xa PF03383.15 CDJ88403.1 - 0.0095 15.9 6.1 0.034 14.1 3.1 2.3 2 1 0 2 2 2 1 Caenorhabditis serpentine receptor-like protein, class xa PK PF00224.21 CDJ88406.1 - 5e-154 512.3 1.5 6.5e-154 512.0 1.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CDJ88406.1 - 2.1e-30 105.4 0.0 8.4e-30 103.4 0.0 2.1 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CDJ88406.1 - 0.00038 19.7 0.9 0.0011 18.2 0.9 1.7 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF3479 PF11965.8 CDJ88406.1 - 0.17 12.0 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) Kinesin PF00225.23 CDJ88407.1 - 2.4e-119 398.1 0.0 2.4e-119 398.1 0.0 2.1 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ88407.1 - 1e-26 93.7 0.8 3.4e-26 92.0 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding Macoilin PF09726.9 CDJ88407.1 - 0.0027 16.3 16.7 0.0033 16.1 16.7 1.2 1 0 0 1 1 1 1 Macoilin family Nbs1_C PF08599.10 CDJ88407.1 - 0.007 16.5 2.0 0.007 16.5 2.0 2.7 1 1 1 2 2 2 1 DNA damage repair protein Nbs1 Kinesin_assoc PF16183.5 CDJ88407.1 - 0.028 14.6 7.9 0.12 12.5 7.5 2.2 1 1 0 1 1 1 0 Kinesin-associated AAA_16 PF13191.6 CDJ88407.1 - 0.038 14.4 0.0 0.038 14.4 0.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain PIF1 PF05970.14 CDJ88407.1 - 0.07 12.3 0.1 0.07 12.3 0.1 1.7 2 0 0 2 2 2 0 PIF1-like helicase eIF3_N PF09440.10 CDJ88407.1 - 0.14 12.6 17.8 0.027 14.9 12.6 2.6 2 1 1 3 3 3 0 eIF3 subunit 6 N terminal domain ADP_PFK_GK PF04587.15 CDJ88408.1 - 0.32 9.5 3.0 4.9 5.6 0.3 2.1 1 1 1 2 2 2 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Recep_L_domain PF01030.24 CDJ88409.1 - 5.7e-12 45.7 1.2 7e-09 35.8 0.0 2.3 2 0 0 2 2 2 2 Receptor L domain PseudoU_synth_1 PF01416.20 CDJ88410.1 - 0.17 12.4 0.0 0.2 12.1 0.0 1.1 1 0 0 1 1 1 0 tRNA pseudouridine synthase DHHC PF01529.20 CDJ88411.1 - 1.8e-35 122.0 13.0 1.8e-35 122.0 13.0 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase PalH PF08733.10 CDJ88411.1 - 0.076 12.0 1.2 0.15 11.0 1.2 1.4 1 0 0 1 1 1 0 PalH/RIM21 DSPc PF00782.20 CDJ88412.1 - 6.1e-15 55.2 0.0 1.3e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Cnd1_N PF12922.7 CDJ88412.1 - 0.016 15.1 0.6 0.04 13.8 0.6 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Y_phosphatase PF00102.27 CDJ88412.1 - 0.075 12.6 1.0 0.087 12.4 0.0 1.6 2 0 0 2 2 2 0 Protein-tyrosine phosphatase RHH_5 PF07878.11 CDJ88412.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 Spt5_N PF11942.8 CDJ88412.1 - 4.2 8.4 16.4 1.4 10.0 6.4 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal ANAPC4_WD40 PF12894.7 CDJ88413.1 - 1.4e-09 38.1 0.3 3.5e-09 36.8 0.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain ANAPC4 PF12896.7 CDJ88413.1 - 2.5e-05 23.9 0.4 2.5e-05 23.9 0.4 2.5 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 WD40 PF00400.32 CDJ88413.1 - 0.049 14.5 0.0 0.15 13.0 0.0 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat Clc-like PF07062.12 CDJ88414.1 - 1.1e-29 103.4 8.7 1.1e-28 100.2 8.7 2.0 1 1 0 1 1 1 1 Clc-like Claudin_2 PF13903.6 CDJ88414.1 - 1.7e-06 28.0 6.6 1.1e-05 25.3 6.6 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4199 PF13858.6 CDJ88414.1 - 5.9 7.3 9.2 1.3 9.4 0.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) Clc-like PF07062.12 CDJ88415.1 - 2.1e-80 269.2 5.2 2.5e-80 269.0 5.2 1.1 1 0 0 1 1 1 1 Clc-like Claudin_2 PF13903.6 CDJ88415.1 - 5.3e-09 36.1 2.1 8.4e-09 35.5 2.1 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF975 PF06161.11 CDJ88415.1 - 0.0043 16.9 1.7 0.0056 16.5 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF975) PMP22_Claudin PF00822.20 CDJ88415.1 - 0.011 15.6 9.7 1 9.2 0.0 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family DuoxA PF10204.9 CDJ88415.1 - 0.055 12.5 5.4 0.079 12.0 5.4 1.1 1 0 0 1 1 1 0 Dual oxidase maturation factor SUR7 PF06687.12 CDJ88415.1 - 0.15 11.7 15.9 0.65 9.6 15.7 1.9 1 1 1 2 2 2 0 SUR7/PalI family Y_phosphatase PF00102.27 CDJ88416.1 - 1e-54 185.6 0.0 1.5e-54 185.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF2442 PF10387.9 CDJ88416.1 - 0.064 13.6 0.4 5.5 7.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2442) Y_phosphatase3 PF13350.6 CDJ88416.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family TRAM_LAG1_CLN8 PF03798.16 CDJ88417.1 - 1e-18 67.8 35.6 1e-18 67.8 35.6 1.5 2 0 0 2 2 2 1 TLC domain Pkinase PF00069.25 CDJ88418.1 - 2.2e-18 66.6 0.0 2.8e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ88418.1 - 4.1e-12 45.9 0.0 4.9e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ88418.1 - 9.9e-05 22.4 0.0 0.092 12.6 0.0 2.2 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CDJ88418.1 - 0.0004 19.8 1.1 0.00067 19.1 0.2 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_S80 PF07230.11 CDJ88418.1 - 0.051 11.9 0.0 0.078 11.3 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) GARS_A PF01071.19 CDJ88419.1 - 1.9e-69 233.4 0.0 3e-69 232.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 CDJ88419.1 - 1.1e-30 106.2 0.0 3.8e-30 104.5 0.0 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 CDJ88419.1 - 1.2e-23 83.2 0.0 3.4e-23 81.7 0.0 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 CDJ88419.1 - 1.9e-07 31.7 0.4 3.9e-07 30.6 0.4 1.5 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp PF02222.22 CDJ88419.1 - 0.00014 21.5 0.0 0.00034 20.2 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain DUF3110 PF11360.8 CDJ88419.1 - 0.13 12.5 0.1 0.33 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) ATPgrasp_ST PF14397.6 CDJ88419.1 - 0.17 11.1 0.0 0.41 9.8 0.0 1.6 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Laminin_EGF PF00053.24 CDJ88420.1 - 5.2e-06 26.5 35.1 0.14 12.3 1.7 4.5 1 1 3 4 4 4 4 Laminin EGF domain RCR PF12273.8 CDJ88420.1 - 0.014 16.0 0.3 0.014 16.0 0.3 2.0 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red EGF_2 PF07974.13 CDJ88420.1 - 0.015 15.6 35.2 0.54 10.7 2.2 4.8 5 0 0 5 5 5 0 EGF-like domain EGF_Tenascin PF18720.1 CDJ88420.1 - 0.63 10.2 29.3 0.06 13.4 4.5 4.8 3 1 1 4 4 4 0 Tenascin EGF domain Ig_3 PF13927.6 CDJ88421.1 - 1.2e-12 48.3 0.0 2.7e-09 37.5 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 CDJ88421.1 - 1.2e-12 47.7 0.0 1.5e-08 34.6 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 CDJ88421.1 - 3.4e-09 36.9 0.0 2.9e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 CDJ88421.1 - 9.5e-05 22.5 0.0 0.5 10.6 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 CDJ88421.1 - 0.00082 18.9 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_5 PF16681.5 CDJ88421.1 - 0.0082 16.5 0.0 0.13 12.7 0.0 2.1 2 0 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set PF07686.17 CDJ88421.1 - 0.015 15.4 0.0 5.7 7.2 0.0 2.9 2 1 1 3 3 3 0 Immunoglobulin V-set domain Amelogenin PF02948.15 CDJ88424.1 - 0.0083 16.8 5.2 0.011 16.4 5.2 1.2 1 0 0 1 1 1 1 Amelogenin DUF5600 PF18150.1 CDJ88426.1 - 7.3e-46 155.2 2.2 7.3e-46 155.2 2.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5600) EHD_N PF16880.5 CDJ88426.1 - 2.3e-16 59.4 4.3 4.5e-16 58.4 4.3 1.5 1 0 0 1 1 1 1 N-terminal EH-domain containing protein EF-hand_4 PF12763.7 CDJ88426.1 - 8.3e-16 57.8 0.0 4.1e-15 55.6 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Dynamin_N PF00350.23 CDJ88426.1 - 2e-14 54.0 0.1 2.8e-13 50.2 0.0 3.0 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 CDJ88426.1 - 1.8e-08 34.5 0.0 4.4e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 CDJ88426.1 - 0.00012 21.3 0.0 0.00063 19.1 0.0 2.3 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CDJ88426.1 - 0.01 15.7 0.1 0.043 13.8 0.1 2.1 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 CDJ88426.1 - 0.019 14.4 0.1 0.062 12.8 0.1 1.9 1 0 0 1 1 1 0 EF hand Roc PF08477.13 CDJ88426.1 - 0.036 14.3 0.0 3.8 7.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase EF-hand_8 PF13833.6 CDJ88426.1 - 0.046 13.6 0.3 5.6 6.9 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain pair RsgA_GTPase PF03193.16 CDJ88426.1 - 0.063 13.2 0.0 4.8 7.0 0.0 2.9 2 1 0 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 CDJ88426.1 - 0.071 13.3 0.1 0.25 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain EF-hand_7 PF13499.6 CDJ88426.1 - 0.13 12.7 0.0 0.64 10.5 0.0 2.2 2 0 0 2 2 1 0 EF-hand domain pair AAA_16 PF13191.6 CDJ88426.1 - 0.18 12.2 0.0 2.1 8.7 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain TPR_2 PF07719.17 CDJ88427.1 - 9.4e-14 50.3 12.2 3.4e-05 23.6 0.9 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ88427.1 - 3.8e-10 39.1 10.4 3.5e-05 23.4 0.3 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ88427.1 - 5.9e-09 36.1 8.4 7.7e-07 29.3 2.8 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ88427.1 - 8.8e-07 29.5 10.9 1.5e-05 25.5 5.1 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ88427.1 - 1e-06 28.8 6.5 5.4e-05 23.3 3.3 3.2 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ88427.1 - 9.9e-06 25.4 7.8 0.15 12.4 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CDJ88427.1 - 0.00011 21.7 3.1 0.0002 20.8 3.1 1.5 1 1 0 1 1 1 1 MalT-like TPR region TPR_14 PF13428.6 CDJ88427.1 - 0.00066 20.3 10.2 0.0091 16.7 1.0 3.6 4 0 0 4 4 3 2 Tetratricopeptide repeat UreF PF01730.16 CDJ88427.1 - 0.019 15.5 0.2 0.046 14.3 0.0 1.8 2 0 0 2 2 2 0 UreF TPR_17 PF13431.6 CDJ88427.1 - 0.027 14.9 2.8 1.2 9.7 0.1 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat Adenine_glyco PF03352.13 CDJ88427.1 - 0.083 12.7 0.3 0.13 12.0 0.3 1.3 1 0 0 1 1 1 0 Methyladenine glycosylase AAA_lid_3 PF17862.1 CDJ88427.1 - 0.15 11.9 1.6 1.2 9.0 0.2 2.7 3 0 0 3 3 3 0 AAA+ lid domain TPR_6 PF13174.6 CDJ88427.1 - 0.19 12.4 9.6 0.63 10.8 0.4 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ88427.1 - 0.32 10.9 8.6 10 6.2 0.2 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ88427.1 - 0.32 11.1 7.2 1.2 9.4 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ88427.1 - 0.33 11.5 8.4 2.2 8.9 3.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ88427.1 - 0.34 11.0 3.9 7.6 6.7 0.5 3.1 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 CDJ88427.1 - 0.88 9.3 7.8 13 5.6 1.0 3.4 2 1 1 3 3 3 0 TPR repeat HemY_N PF07219.13 CDJ88427.1 - 1.1 9.5 3.7 4.7 7.5 0.8 2.8 1 1 2 3 3 3 0 HemY protein N-terminus ParD_antitoxin PF03693.14 CDJ88427.1 - 2.4 8.6 4.9 16 6.0 0.2 2.8 2 1 0 2 2 2 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH VWA PF00092.28 CDJ88428.1 - 6.8e-32 111.1 1.1 6.1e-22 78.7 0.2 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 CDJ88428.1 - 4.5e-15 56.2 0.1 1.5e-11 44.8 0.0 2.6 2 0 0 2 2 2 2 von Willebrand factor type A domain PIEZO PF15917.5 CDJ88428.1 - 0.069 12.6 1.9 0.16 11.4 1.9 1.6 1 0 0 1 1 1 0 Piezo FixQ PF05545.11 CDJ88428.1 - 0.074 13.0 0.5 0.24 11.4 0.5 1.9 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Amidase02_C PF12123.8 CDJ88428.1 - 0.087 12.5 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase Ly49 PF08391.10 CDJ88428.1 - 0.14 12.5 1.4 0.35 11.2 1.4 1.6 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region OmpH PF03938.14 CDJ88428.1 - 0.42 11.0 6.4 0.97 9.8 6.4 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Gelsolin PF00626.22 CDJ88428.1 - 0.45 10.5 3.2 11 6.0 2.2 2.6 2 0 0 2 2 2 0 Gelsolin repeat DUF851 PF05867.11 CDJ88429.1 - 4.6e-12 45.9 0.1 4.6e-12 45.9 0.1 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF851) UCH_C PF18031.1 CDJ88430.1 - 0.011 15.6 0.5 0.027 14.4 0.5 1.7 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolases GldM_N PF12081.8 CDJ88430.1 - 0.35 10.9 4.0 0.83 9.7 4.0 1.5 1 1 0 1 1 1 0 GldM N-terminal domain DUF851 PF05867.11 CDJ88431.1 - 4.2e-12 46.1 0.0 4.2e-12 46.1 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF851) Apt1 PF10351.9 CDJ88431.1 - 0.59 8.9 13.9 0.78 8.5 13.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ88431.1 - 1 7.8 15.3 1.3 7.5 15.3 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 CDJ88431.1 - 1.3 7.7 10.0 1.6 7.4 10.0 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CDJ88431.1 - 5.5 5.5 6.9 6.9 5.2 6.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.16 CDJ88431.1 - 8.3 6.4 8.9 15 5.6 8.9 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RVT_1 PF00078.27 CDJ88432.1 - 9.8e-39 133.1 0.0 1.6e-38 132.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CAP PF00188.26 CDJ88433.1 - 2e-17 64.2 0.7 2e-17 64.2 0.7 2.6 2 1 0 2 2 2 1 Cysteine-rich secretory protein family CAP PF00188.26 CDJ88434.1 - 9e-18 65.3 0.8 9e-18 65.3 0.8 2.7 2 1 0 2 2 2 1 Cysteine-rich secretory protein family ATP-synt_F6 PF05511.11 CDJ88434.1 - 0.16 12.4 0.4 0.63 10.5 0.1 2.0 1 1 1 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 UNC-93 PF05978.16 CDJ88435.1 - 2.3e-54 183.3 12.9 2.3e-54 183.3 12.9 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 CDJ88435.1 - 7.6e-12 44.8 23.8 7.6e-12 44.8 23.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily PDR_assoc PF08370.11 CDJ88435.1 - 0.078 12.7 0.5 0.078 12.7 0.5 2.6 2 1 1 3 3 3 0 Plant PDR ABC transporter associated DcpS PF05652.12 CDJ88437.1 - 4.2e-13 50.0 0.0 7.7e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal CAP PF00188.26 CDJ88440.1 - 2.9e-08 34.6 0.1 3.6e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family HTH_Bact PF18768.1 CDJ88440.1 - 0.052 13.1 0.1 0.075 12.6 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix bacterial domain LBP_BPI_CETP_C PF02886.17 CDJ88441.1 - 3.8e-62 209.8 0.0 5.4e-62 209.4 0.0 1.2 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain MtN3_slv PF03083.16 CDJ88444.1 - 5.9e-54 180.1 6.1 4.8e-26 90.6 0.1 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 CDJ88444.1 - 0.0054 16.5 3.2 0.0086 15.8 0.1 2.8 3 1 0 3 3 3 1 PQ loop repeat LAB_N PF07578.11 CDJ88444.1 - 0.031 14.3 2.8 0.22 11.6 0.1 2.9 2 1 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain 6PGD PF00393.19 CDJ88445.1 - 1e-124 415.7 0.0 1.2e-124 415.5 0.0 1.0 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CDJ88445.1 - 0.00019 21.7 0.0 0.00037 20.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CDJ88445.1 - 0.0051 17.1 0.6 0.029 14.6 0.1 2.3 3 0 0 3 3 3 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase zf-C2H2 PF00096.26 CDJ88446.1 - 0.00012 22.3 3.1 0.00012 22.3 3.1 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ88446.1 - 5 7.7 9.2 1.6 9.3 0.6 3.1 3 0 0 3 3 3 0 Zinc-finger double domain PI3_PI4_kinase PF00454.27 CDJ88447.1 - 3.3e-40 138.5 0.0 5.9e-40 137.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CDJ88447.1 - 3.1e-12 46.1 0.2 2.8e-11 43.0 0.0 2.6 3 0 0 3 3 3 1 FATC domain DUF4042 PF13251.6 CDJ88447.1 - 0.083 12.6 2.4 0.7 9.6 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) DUF5471 PF17565.2 CDJ88447.1 - 0.13 12.6 0.0 0.47 10.8 0.0 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5471) ANAPC3 PF12895.7 CDJ88447.1 - 0.4 10.9 2.9 39 4.6 0.0 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Phage_int_SAM_6 PF18644.1 CDJ88448.1 - 0.041 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Phage integrase SAM-like domain Ank_2 PF12796.7 CDJ88449.1 - 9.8e-31 106.2 6.9 4.3e-10 40.1 0.2 5.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDJ88449.1 - 7.7e-26 87.3 5.7 0.0099 16.3 0.1 8.7 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 CDJ88449.1 - 1.9e-24 85.4 3.6 7.6e-05 22.9 0.1 6.6 2 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDJ88449.1 - 4.1e-21 75.1 3.9 5e-05 23.8 0.0 7.3 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 CDJ88449.1 - 2.3e-13 49.9 5.0 0.37 11.3 0.2 7.0 6 0 0 6 6 6 4 Ankyrin repeat BTB PF00651.31 CDJ88449.1 - 1.7e-11 44.3 0.0 3.5e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 CDJ88449.1 - 0.016 15.3 0.1 0.14 12.3 0.0 2.3 2 1 0 2 2 2 0 BTB And C-terminal Kelch Aldolase PF01081.19 CDJ88449.1 - 0.071 12.5 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 KDPG and KHG aldolase IMPDH PF00478.25 CDJ88450.1 - 1.8e-126 421.8 2.4 2.1e-126 421.6 2.4 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CDJ88450.1 - 8.2e-13 48.6 0.1 0.00014 22.2 0.0 3.4 3 0 0 3 3 3 2 CBS domain NMO PF03060.15 CDJ88450.1 - 2e-09 37.3 3.0 2e-06 27.5 3.4 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 CDJ88450.1 - 3.8e-08 32.8 2.5 8.2e-08 31.6 2.5 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 CDJ88450.1 - 3.2e-05 23.5 2.8 0.0001 21.9 2.8 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein B12-binding PF02310.19 CDJ88450.1 - 0.0062 16.6 0.0 0.018 15.0 0.0 1.8 1 0 0 1 1 1 1 B12 binding domain Aldolase PF01081.19 CDJ88450.1 - 0.12 11.8 1.5 0.14 11.6 0.2 1.8 2 0 0 2 2 2 0 KDPG and KHG aldolase ThiG PF05690.14 CDJ88450.1 - 0.69 9.2 5.1 0.87 8.8 3.5 1.9 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG PcrB PF01884.17 CDJ88450.1 - 1.1 8.6 4.5 7.6 5.9 0.0 3.3 3 1 1 4 4 4 0 PcrB family RVT_1 PF00078.27 CDJ88451.1 - 1.9e-08 34.1 0.0 1.9e-08 34.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7TM_GPCR_Srv PF10323.9 CDJ88453.1 - 1.3e-53 182.2 26.3 1.5e-53 182.0 26.3 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Srg PF02118.21 CDJ88453.1 - 2.4e-07 30.7 28.1 3.2e-07 30.3 28.1 1.1 1 0 0 1 1 1 1 Srg family chemoreceptor 7tm_1 PF00001.21 CDJ88453.1 - 1.6e-05 24.4 16.2 2.5e-05 23.8 16.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Phage_holin_3_6 PF07332.11 CDJ88453.1 - 0.27 11.3 1.6 2.6 8.1 0.1 2.7 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III HemY_N PF07219.13 CDJ88454.1 - 0.17 12.1 0.9 0.34 11.1 0.9 1.5 1 1 0 1 1 1 0 HemY protein N-terminus Neur_chan_LBD PF02931.23 CDJ88455.1 - 2.3e-29 102.4 0.9 4.1e-29 101.6 0.2 1.7 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain COG5 PF10392.9 CDJ88456.1 - 0.015 15.5 0.7 0.021 15.0 0.7 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 SKA1 PF07160.12 CDJ88456.1 - 0.027 14.3 0.1 0.034 14.0 0.1 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Laminin_II PF06009.12 CDJ88456.1 - 0.11 12.5 1.1 0.18 11.8 1.1 1.3 1 1 0 1 1 1 0 Laminin Domain II Pkinase_Tyr PF07714.17 CDJ88457.1 - 7e-56 189.4 0.0 9e-56 189.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ88457.1 - 1e-35 123.4 0.0 1.5e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDJ88457.1 - 0.00014 21.9 0.0 0.00034 20.6 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Kinase-like PF14531.6 CDJ88457.1 - 0.002 17.5 0.0 0.0042 16.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Cse1 PF08506.10 CDJ88459.1 - 1.3e-122 409.2 1.0 1.8e-122 408.8 1.0 1.2 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 CDJ88459.1 - 1.4e-59 201.7 0.6 3.5e-59 200.4 0.1 1.8 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 CDJ88459.1 - 3.7e-13 49.2 0.0 1.3e-12 47.4 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 CDJ88459.1 - 0.0037 15.9 0.9 2.2 6.7 0.0 3.3 2 1 0 2 2 2 2 Adaptin N terminal region Xpo1 PF08389.12 CDJ88459.1 - 0.0058 16.7 0.5 0.074 13.1 0.1 3.0 3 0 0 3 3 3 1 Exportin 1-like protein Adeno_E1B_19K PF01691.16 CDJ88459.1 - 0.02 14.4 0.3 7.6 6.1 0.0 3.5 3 0 0 3 3 3 0 Adenovirus E1B 19K protein / small t-antigen Ints3 PF10189.9 CDJ88459.1 - 0.089 12.0 0.9 0.37 10.0 0.6 2.2 2 0 0 2 2 2 0 Integrator complex subunit 3 bZIP_Maf PF03131.17 CDJ88460.1 - 2.1e-10 41.0 4.9 4.7e-10 39.9 4.9 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF5364 PF17322.2 CDJ88460.1 - 0.016 15.5 1.9 0.021 15.1 1.3 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5364) MdcE PF06833.11 CDJ88460.1 - 0.098 12.1 0.2 0.13 11.8 0.2 1.1 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) bZIP_1 PF00170.21 CDJ88460.1 - 0.23 11.6 13.2 0.09 12.9 10.1 1.9 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.15 CDJ88460.1 - 0.34 11.0 8.9 0.59 10.3 8.0 1.9 1 1 0 1 1 1 0 Basic region leucine zipper Fucokinase PF07959.12 CDJ88464.1 - 1.6e-10 40.5 0.1 1e-08 34.6 0.0 2.7 2 1 0 2 2 2 1 L-fucokinase GHMP_kinases_N PF00288.26 CDJ88464.1 - 3e-06 27.4 0.3 3e-06 27.4 0.3 2.6 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CDJ88464.1 - 0.00021 21.6 0.0 0.00075 19.8 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal 7TM_GPCR_Srt PF10321.9 CDJ88465.1 - 1.4e-76 257.4 28.1 1.6e-76 257.2 28.1 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt 7TM_GPCR_Srx PF10328.9 CDJ88465.1 - 2.3e-10 40.6 25.6 2.8e-10 40.3 25.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4735 PF15882.5 CDJ88465.1 - 0.11 12.0 0.6 0.16 11.4 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) Ndc1_Nup PF09531.10 CDJ88465.1 - 6.9 5.2 10.8 13 4.4 10.6 1.4 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Glyco_hydro_31 PF01055.26 CDJ88466.1 - 1.6e-131 439.5 12.4 2.4e-131 439.0 12.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 CDJ88466.1 - 1.2e-18 67.3 0.0 2.3e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 CDJ88466.1 - 8.5e-08 32.0 4.5 8.5e-08 32.0 4.5 1.7 2 0 0 2 2 2 1 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.6 CDJ88466.1 - 1.1e-05 25.7 0.3 1.1e-05 25.7 0.3 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like Peptidase_S31 PF05578.12 CDJ88466.1 - 0.087 12.3 0.0 0.97 8.9 0.0 2.2 2 0 0 2 2 2 0 Pestivirus NS3 polyprotein peptidase S31 DUF1759 PF03564.15 CDJ88467.1 - 4.8e-06 26.6 0.5 0.00019 21.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1759) WXG100 PF06013.12 CDJ88467.1 - 0.035 14.3 1.4 0.054 13.7 0.3 1.9 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Skp1 PF01466.19 CDJ88469.1 - 1.9e-30 104.7 1.0 3e-30 104.1 1.0 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 CDJ88469.1 - 4.7e-20 71.5 0.1 1.2e-19 70.2 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Myb_DNA-binding PF00249.31 CDJ88469.1 - 0.15 12.3 0.7 19 5.5 0.3 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain Sec3_C PF09763.9 CDJ88470.1 - 1.7e-98 330.8 6.6 2.5e-98 330.3 6.6 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 CDJ88470.1 - 4e-16 58.9 0.0 1.2e-15 57.4 0.0 1.8 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH PH PF00169.29 CDJ88470.1 - 0.025 15.1 0.0 0.1 13.1 0.0 2.1 1 0 0 1 1 1 0 PH domain Baculo_PEP_C PF04513.12 CDJ88470.1 - 0.097 12.7 2.0 59 3.7 3.5 3.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LcrG PF07216.12 CDJ88470.1 - 1.2 9.1 3.4 9.4 6.2 0.1 3.7 4 0 0 4 4 4 0 LcrG protein CCDC-167 PF15188.6 CDJ88470.1 - 7.2 7.0 11.2 3 8.2 2.4 4.2 5 0 0 5 5 5 0 Coiled-coil domain-containing protein 167 ER_lumen_recept PF00810.18 CDJ88471.1 - 1.4e-42 145.9 6.1 2.3e-42 145.3 6.1 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF3810 PF12725.7 CDJ88471.1 - 0.47 9.7 5.9 0.55 9.5 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF3155 PF11352.8 CDJ88472.1 - 2 8.9 9.0 19 5.8 0.1 4.6 2 1 4 6 6 6 0 Protein of unknown function (DUF3155) Prominin PF05478.11 CDJ88473.1 - 1.6e-83 281.1 14.9 2e-83 280.8 14.9 1.0 1 0 0 1 1 1 1 Prominin DUF5600 PF18150.1 CDJ88473.1 - 0.0076 16.8 0.0 0.0076 16.8 0.0 3.6 4 1 1 5 5 5 1 Domain of unknown function (DUF5600) Claudin_3 PF06653.11 CDJ88473.1 - 0.009 16.0 3.6 0.009 16.0 3.6 3.1 3 0 0 3 3 3 1 Tight junction protein, Claudin-like Apolipoprotein PF01442.18 CDJ88473.1 - 0.026 14.4 0.6 0.026 14.4 0.6 2.9 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain Shikimate_DH PF01488.20 CDJ88473.1 - 0.068 13.2 0.2 0.28 11.2 0.2 2.1 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FtsX PF02687.21 CDJ88473.1 - 0.095 13.2 3.8 9.2 6.8 1.7 3.0 2 0 0 2 2 2 0 FtsX-like permease family Rnk_N PF14760.6 CDJ88473.1 - 0.11 13.0 0.1 0.5 10.9 0.1 2.2 1 0 0 1 1 1 0 Rnk N-terminus DUF885 PF05960.11 CDJ88473.1 - 0.31 10.6 5.1 0.074 12.7 1.6 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) Muted PF14942.6 CDJ88473.1 - 0.48 10.8 17.0 0.09 13.1 4.2 3.4 2 2 1 3 3 3 0 Organelle biogenesis, Muted-like protein FliT PF05400.13 CDJ88473.1 - 1.4 9.8 5.5 1.4 9.8 1.2 3.1 1 1 1 2 2 2 0 Flagellar protein FliT ApoLp-III PF07464.11 CDJ88473.1 - 2.6 8.1 15.4 5.8 7.0 4.2 3.8 2 2 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 CDJ88473.1 - 3.9 7.5 21.0 0.13 12.3 1.1 4.6 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DB PF01682.19 CDJ88474.1 - 5.6e-17 61.9 10.9 5.6e-17 61.9 10.9 1.4 2 0 0 2 2 2 1 DB module KicB PF03882.14 CDJ88475.1 - 0.047 13.9 0.1 0.073 13.3 0.1 1.2 1 0 0 1 1 1 0 MukF winged-helix domain Ribosomal_L18_c PF14204.6 CDJ88475.1 - 0.35 11.8 3.3 0.23 12.4 0.5 1.9 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region LRRNT PF01462.18 CDJ88475.1 - 1.6 8.5 5.6 4.9 6.9 0.4 2.7 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain eIF3g PF12353.8 CDJ88475.1 - 4 7.8 16.9 0.2 12.1 0.9 3.5 1 1 3 4 4 4 0 Eukaryotic translation initiation factor 3 subunit G UQ_con PF00179.26 CDJ88477.1 - 2.4e-39 134.2 0.0 2.9e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ88477.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UQ_con PF00179.26 CDJ88478.1 - 4e-42 143.2 0.0 4.6e-42 143.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ88478.1 - 0.0017 18.0 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B YEATS PF03366.16 CDJ88480.1 - 1.1e-29 102.2 0.3 1.6e-29 101.7 0.3 1.3 1 0 0 1 1 1 1 YEATS family DUF4849 PF16141.5 CDJ88480.1 - 0.055 12.7 0.1 0.11 11.7 0.0 1.5 2 0 0 2 2 2 0 Putative glycoside hydrolase Family 18, chitinase_18 FlbD PF06289.11 CDJ88480.1 - 0.12 12.0 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 Flagellar and Swarming motility proteins EF-hand_6 PF13405.6 CDJ88481.1 - 1.2e-08 34.2 1.1 0.00016 21.3 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CDJ88481.1 - 1.2e-08 35.3 1.2 1.2e-08 35.3 1.2 3.6 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 CDJ88481.1 - 0.017 14.6 10.7 0.13 11.9 0.1 3.8 4 1 0 4 4 4 0 EF hand EF-hand_5 PF13202.6 CDJ88481.1 - 0.041 13.4 8.8 0.4 10.3 0.1 3.6 4 0 0 4 4 4 0 EF hand Ribosomal_S13 PF00416.22 CDJ88481.1 - 1.3 9.4 9.0 1.3 9.5 3.0 3.0 2 1 1 3 3 3 0 Ribosomal protein S13/S18 Rx_N PF18052.1 CDJ88481.1 - 1.9 8.8 13.1 1.1 9.5 0.1 3.0 3 0 0 3 3 3 0 Rx N-terminal domain Amidinotransf PF02274.17 CDJ88483.1 - 2.6e-18 66.2 0.0 9e-18 64.5 0.0 1.7 1 1 0 1 1 1 1 Amidinotransferase Msg2_C PF12373.8 CDJ88483.1 - 0.04 13.3 0.0 0.09 12.2 0.0 1.6 1 0 0 1 1 1 0 Major surface glycoprotein 2 C terminal LRR_4 PF12799.7 CDJ88484.1 - 5.8e-45 150.5 60.1 3.8e-09 36.7 0.9 6.6 1 1 10 11 11 11 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ88484.1 - 8.2e-23 79.9 30.9 1.5e-06 27.8 1.7 6.1 1 1 3 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 CDJ88484.1 - 2.8e-21 75.8 18.2 1.7e-09 37.4 0.3 4.2 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 CDJ88484.1 - 0.018 15.5 26.5 38 5.4 0.1 9.5 9 2 0 9 9 9 0 Leucine Rich Repeat LRR_6 PF13516.6 CDJ88484.1 - 0.36 11.0 23.6 13 6.1 0.4 7.4 8 0 0 8 8 8 0 Leucine Rich repeat DDOST_48kD PF03345.14 CDJ88485.1 - 2.2e-140 468.2 0.0 2.6e-140 467.9 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta HTH_48 PF17906.1 CDJ88485.1 - 5.8e-13 48.7 0.0 1.3e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase Metallopep PF12044.8 CDJ88486.1 - 2.3e-06 26.5 0.8 3.6e-06 25.9 0.8 1.2 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_3 PF13582.6 CDJ88486.1 - 0.13 12.8 0.3 0.24 11.9 0.3 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Tubulin PF00091.25 CDJ88487.1 - 5.8e-64 215.9 0.0 8.7e-64 215.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDJ88487.1 - 9.8e-43 145.3 0.0 1.7e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CDJ88487.1 - 0.0038 16.9 0.0 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 Tubulin domain Tubulin_2 PF13809.6 CDJ88487.1 - 0.039 13.1 0.0 0.063 12.4 0.0 1.2 1 0 0 1 1 1 0 Tubulin like CAP_GLY PF01302.25 CDJ88488.1 - 1e-18 67.1 1.1 1.8e-18 66.3 1.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain 6PGD PF00393.19 CDJ88489.1 - 1.9e-93 313.0 0.0 2.1e-93 312.9 0.0 1.0 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CDJ88489.1 - 0.00014 22.1 0.0 0.00028 21.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CDJ88489.1 - 0.0071 16.6 0.3 0.019 15.2 0.0 1.8 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Exo_endo_phos PF03372.23 CDJ88490.1 - 2.3e-05 24.0 0.0 3.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NAD_binding_2 PF03446.15 CDJ88491.1 - 2.5e-40 138.2 0.1 3e-40 138.0 0.1 1.0 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DNA_pol3_beta PF00712.19 CDJ88491.1 - 0.02 15.0 0.0 0.029 14.5 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain F420_oxidored PF03807.17 CDJ88491.1 - 0.049 14.2 0.1 0.08 13.5 0.1 1.5 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 CDJ88491.1 - 0.063 12.9 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DRTGG PF07085.12 CDJ88491.1 - 0.13 12.1 0.1 22 4.9 0.0 2.3 1 1 0 2 2 2 0 DRTGG domain SCAB_CC PF16712.5 CDJ88491.1 - 0.14 12.0 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein 3HCDH_N PF02737.18 CDJ88491.1 - 0.18 11.6 0.1 0.37 10.7 0.1 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RVT_1 PF00078.27 CDJ88492.1 - 3.5e-39 134.6 0.0 7e-39 133.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GIY-YIG PF01541.24 CDJ88493.1 - 0.00015 21.9 0.0 0.00029 21.0 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain Thioredoxin_15 PF18403.1 CDJ88494.1 - 9.4e-24 84.5 0.0 1.1e-23 84.4 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin-like domain DUF2117 PF09890.9 CDJ88494.1 - 0.0041 16.6 0.0 0.0041 16.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2117) Chi-conotoxin PF16981.5 CDJ88495.1 - 0.13 12.5 0.1 0.46 10.7 0.1 2.0 1 0 0 1 1 1 0 chi-Conotoxin or t superfamily Chi-conotoxin PF16981.5 CDJ88496.1 - 0.14 12.4 0.6 0.42 10.9 0.6 2.0 1 1 0 1 1 1 0 chi-Conotoxin or t superfamily EVI2A PF05399.11 CDJ88496.1 - 0.6 9.7 4.9 0.79 9.3 4.9 1.3 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) PA26 PF04636.13 CDJ88496.1 - 6 5.7 5.2 6.7 5.5 5.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Presenilin PF01080.17 CDJ88496.1 - 7.3 5.2 16.2 10 4.8 16.2 1.3 1 0 0 1 1 1 0 Presenilin SPARC_Ca_bdg PF10591.9 CDJ88497.1 - 3.1e-16 59.7 3.5 3.1e-16 59.7 3.5 3.2 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Thyroglobulin_1 PF00086.18 CDJ88497.1 - 2.7e-14 52.6 3.5 2.7e-14 52.6 3.5 2.3 3 0 0 3 3 3 1 Thyroglobulin type-1 repeat EF-hand_1 PF00036.32 CDJ88497.1 - 1.9e-06 27.0 0.2 0.0034 16.8 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CDJ88497.1 - 9.2e-05 21.8 0.1 0.024 14.2 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CDJ88497.1 - 0.00046 19.9 0.0 0.11 12.5 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 CDJ88497.1 - 0.0022 18.4 1.4 0.0047 17.3 0.6 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CDJ88497.1 - 0.0078 16.0 2.4 0.17 11.7 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair Zip PF02535.22 CDJ88497.1 - 8.1 5.6 8.1 11 5.1 8.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TRAM_LAG1_CLN8 PF03798.16 CDJ88498.1 - 1e-18 67.8 35.6 1e-18 67.8 35.6 1.6 2 0 0 2 2 2 1 TLC domain polyprenyl_synt PF00348.17 CDJ88499.1 - 9.8e-71 237.8 0.3 1.2e-70 237.5 0.3 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase BacteriocIIc_cy PF12173.8 CDJ88499.1 - 0.038 14.2 0.1 0.12 12.7 0.1 1.8 2 0 0 2 2 2 0 Bacteriocin class IIc cyclic gassericin A-like DUF3251 PF11622.8 CDJ88499.1 - 0.07 12.8 0.1 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3251) Thioredoxin_6 PF13848.6 CDJ88500.1 - 3.1e-49 167.4 0.2 4.9e-42 143.9 0.0 3.0 1 1 2 3 3 3 3 Thioredoxin-like domain Thioredoxin PF00085.20 CDJ88500.1 - 9.4e-23 80.2 0.2 2.8e-22 78.7 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.13 CDJ88500.1 - 0.00018 21.0 0.8 0.00053 19.4 0.2 2.0 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CDJ88500.1 - 0.0034 17.5 0.1 0.051 13.8 0.2 2.3 2 0 0 2 2 2 1 Thioredoxin-like HyaE PF07449.11 CDJ88500.1 - 0.0059 16.6 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 CDJ88500.1 - 0.012 16.0 0.0 0.042 14.3 0.0 2.0 1 0 0 1 1 1 0 Thioredoxin-like domain ERp29_N PF07912.13 CDJ88500.1 - 0.017 15.2 0.1 0.099 12.8 0.1 2.2 2 1 0 2 2 2 0 ERp29, N-terminal domain Thioredoxin_8 PF13905.6 CDJ88500.1 - 0.019 15.3 0.2 0.59 10.5 0.1 2.8 2 1 1 3 3 3 0 Thioredoxin-like PAP2 PF01569.21 CDJ88501.1 - 3.2e-24 85.3 0.2 5.2e-24 84.6 0.2 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 CDJ88501.1 - 1.1e-10 41.5 1.1 1.4e-10 41.2 1.1 1.3 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 CDJ88501.1 - 0.21 12.2 1.0 0.54 10.8 0.0 2.0 2 1 1 3 3 3 0 PAP2 superfamily C-terminal Polysacc_synt_C PF14667.6 CDJ88501.1 - 0.25 11.4 4.7 2 8.5 0.1 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Arfaptin PF06456.13 CDJ88502.1 - 3e-43 148.0 2.1 4.5e-43 147.5 0.9 1.8 1 1 1 2 2 2 1 Arfaptin-like domain Ets PF00178.22 CDJ88503.1 - 2.1e-29 101.8 0.0 3.3e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Ets-domain RVT_1 PF00078.27 CDJ88504.1 - 4.1e-38 131.1 0.0 7e-38 130.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_8 PF13855.6 CDJ88505.1 - 1.2e-18 66.6 22.4 1.4e-09 37.5 4.0 4.4 4 1 1 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 CDJ88505.1 - 2e-13 50.3 20.0 1.9e-05 24.9 0.6 5.8 3 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDJ88505.1 - 4.8e-07 29.4 18.2 2 9.3 0.1 7.4 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_9 PF14580.6 CDJ88505.1 - 4e-05 23.2 3.3 0.00033 20.2 1.9 2.2 1 1 1 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.6 CDJ88505.1 - 0.18 11.9 16.8 2.7 8.3 0.1 5.9 6 0 0 6 6 6 0 Leucine Rich repeat Aldedh PF00171.22 CDJ88507.1 - 1.2e-149 498.8 0.0 1.5e-149 498.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PGK PF00162.19 CDJ88509.1 - 1.7e-151 504.5 0.8 1.9e-151 504.3 0.8 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PGK PF00162.19 CDJ88510.1 - 6.5e-154 512.4 1.8 7.4e-154 512.3 1.8 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 CDJ88510.1 - 0.032 14.2 0.8 0.26 11.3 0.0 2.8 3 0 0 3 3 3 0 PA domain MRP-S35 PF10246.9 CDJ88511.1 - 8.3e-45 151.1 0.0 1.3e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein MRP-S35 Voltage_CLC PF00654.20 CDJ88512.1 - 6.6e-95 318.3 19.0 6.6e-95 318.3 19.0 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CDJ88512.1 - 8e-14 51.8 0.3 1.1e-05 25.7 0.0 2.5 2 0 0 2 2 2 2 CBS domain Phage_holin_3_3 PF16083.5 CDJ88512.1 - 0.019 15.1 0.6 0.019 15.1 0.6 5.5 4 2 1 5 5 5 0 LydA holin phage, holin superfamily III GtrA PF04138.14 CDJ88512.1 - 1.1 9.5 8.3 1.3 9.2 1.5 3.5 1 1 0 2 2 2 0 GtrA-like protein GerE PF00196.19 CDJ88513.1 - 0.025 14.1 0.0 0.41 10.2 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, luxR family Homeodomain PF00046.29 CDJ88513.1 - 0.086 12.7 0.1 0.32 10.9 0.1 2.0 1 0 0 1 1 1 0 Homeodomain KORA PF16509.5 CDJ88513.1 - 0.11 12.8 0.0 0.35 11.2 0.0 1.8 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor Ribosomal_L5e PF17144.4 CDJ88514.1 - 4.9e-81 270.5 1.1 8.1e-81 269.8 1.1 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CDJ88514.1 - 5.4e-36 123.4 6.1 5.4e-36 123.4 6.1 2.1 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF1476 PF07345.11 CDJ88514.1 - 0.0027 18.0 0.4 0.0075 16.6 0.4 1.7 1 0 0 1 1 1 1 ATPase inhibitor subunit zeta Thg1C PF14413.6 CDJ88514.1 - 0.27 11.4 4.6 0.21 11.8 0.7 2.3 2 1 1 3 3 3 0 Thg1 C terminal domain HMGL-like PF00682.19 CDJ88515.1 - 2.5e-52 178.0 0.0 3e-52 177.8 0.0 1.0 1 0 0 1 1 1 1 HMGL-like Ribosomal_L5 PF00281.19 CDJ88516.1 - 1.1e-21 76.9 0.1 8.4e-21 74.1 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 CDJ88516.1 - 3.7e-20 71.9 0.0 7.1e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Sarcoglycan_1 PF04790.13 CDJ88517.1 - 1.6e-64 217.7 0.0 1.9e-64 217.6 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.9 CDJ88517.1 - 0.0036 17.2 0.0 0.016 15.1 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2345) fn3 PF00041.21 CDJ88518.1 - 6.1e-23 81.0 5.2 2.5e-05 24.5 0.0 7.5 7 0 0 7 7 7 4 Fibronectin type III domain MFS_1 PF07690.16 CDJ88519.1 - 1e-47 162.8 38.1 3.5e-42 144.6 33.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ88519.1 - 0.17 10.7 36.7 0.011 14.6 9.4 3.8 2 2 1 3 3 3 0 Sugar (and other) transporter Voltage_CLC PF00654.20 CDJ88520.1 - 4e-74 250.0 31.0 5e-74 249.7 31.0 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 CDJ88520.1 - 1.6e-06 28.5 0.2 0.054 14.0 0.1 2.5 2 0 0 2 2 2 2 CBS domain Phospholip_B PF04916.13 CDJ88522.1 - 4.6e-171 570.0 1.5 5.7e-171 569.7 1.5 1.0 1 0 0 1 1 1 1 Phospholipase B Pkinase PF00069.25 CDJ88524.1 - 2.8e-67 226.9 0.0 4e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ88524.1 - 3.9e-28 98.5 0.0 6.8e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ88524.1 - 2.3e-06 26.7 0.0 4.9e-06 25.6 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CDJ88524.1 - 9.3e-05 21.9 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDJ88524.1 - 0.001 18.4 0.0 0.0048 16.2 0.0 2.1 2 1 0 2 2 2 1 Kinase-like NMD3 PF04981.13 CDJ88524.1 - 0.06 12.8 0.1 0.18 11.3 0.1 1.8 2 0 0 2 2 2 0 NMD3 family Neur_chan_LBD PF02931.23 CDJ88525.1 - 4.9e-17 62.1 3.1 6.9e-17 61.6 3.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF2070 PF09843.9 CDJ88525.1 - 0.44 8.8 9.2 0.54 8.5 9.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) FtsX PF02687.21 CDJ88525.1 - 1.5 9.4 7.5 0.3 11.6 3.3 2.0 2 0 0 2 2 2 0 FtsX-like permease family TrbC PF04956.13 CDJ88525.1 - 3.7 7.8 10.4 11 6.3 0.4 2.5 2 1 0 2 2 2 0 TrbC/VIRB2 family Pyridoxal_deC PF00282.19 CDJ88526.1 - 0.017 13.9 0.1 0.026 13.2 0.1 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain zf-C2H2 PF00096.26 CDJ88528.1 - 5.9e-17 61.1 21.9 4.3e-06 26.9 1.7 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ88528.1 - 7.2e-14 51.5 22.4 8e-07 29.2 0.9 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDJ88528.1 - 6.3e-12 45.3 18.5 0.00095 19.8 0.8 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDJ88528.1 - 8.6e-10 38.4 15.5 4.7e-05 23.3 0.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ88528.1 - 4.6e-09 36.3 8.1 0.00073 19.8 1.0 3.5 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding XPA_N PF01286.18 CDJ88528.1 - 0.077 13.1 3.7 21 5.3 0.2 3.6 3 0 0 3 3 3 0 XPA protein N-terminal GAGA PF09237.11 CDJ88528.1 - 0.099 12.5 1.3 0.22 11.3 0.3 2.1 1 1 1 2 2 2 0 GAGA factor DZR PF12773.7 CDJ88528.1 - 0.15 12.1 5.5 1.5 8.9 5.5 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_11 PF16622.5 CDJ88528.1 - 0.17 11.6 0.3 0.17 11.6 0.3 3.3 3 1 0 3 3 3 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 CDJ88528.1 - 0.42 10.8 3.7 8.3 6.6 0.9 2.7 2 1 0 2 2 2 0 Zinc ribbon domain zf-LYAR PF08790.11 CDJ88528.1 - 0.46 10.4 0.2 0.46 10.4 0.2 3.0 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 CDJ88528.1 - 0.52 10.7 10.1 0.53 10.6 1.9 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 CDJ88528.1 - 0.59 10.2 14.0 4.7 7.3 2.0 3.5 1 1 2 3 3 3 0 BED zinc finger zf-met PF12874.7 CDJ88528.1 - 0.64 10.5 14.9 0.83 10.1 0.9 3.7 4 0 0 4 4 3 0 Zinc-finger of C2H2 type zf-MYST PF17772.1 CDJ88528.1 - 1 9.0 4.3 47 3.7 0.1 3.4 1 1 2 3 3 3 0 MYST family zinc finger domain MtrG PF04210.13 CDJ88529.1 - 0.33 10.8 0.9 2.2 8.2 0.4 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF1451 PF07295.11 CDJ88529.1 - 0.9 9.6 5.7 0.14 12.2 1.1 2.1 2 1 0 2 2 2 0 Zinc-ribbon containing domain DUF5593 PF18007.1 CDJ88529.1 - 1.9 9.2 7.4 21 5.9 0.1 3.8 2 1 2 4 4 4 0 Domain of unknown function (DUF5593) HHH_2 PF12826.7 CDJ88529.1 - 3.2 7.9 5.7 5.2 7.2 0.1 2.8 3 0 0 3 3 3 0 Helix-hairpin-helix motif RVT_1 PF00078.27 CDJ88530.1 - 8.4e-18 64.7 0.0 8.9e-18 64.6 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Aldedh PF00171.22 CDJ88531.1 - 4e-121 404.7 0.4 5.5e-121 404.3 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family YCII PF03795.14 CDJ88531.1 - 0.064 13.7 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 YCII-related domain Aldedh PF00171.22 CDJ88532.1 - 1.5e-130 435.8 0.6 1.9e-130 435.5 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRF PF01765.19 CDJ88532.1 - 0.0087 16.0 0.9 0.016 15.2 0.9 1.3 1 0 0 1 1 1 1 Ribosome recycling factor Aldedh PF00171.22 CDJ88533.1 - 1e-130 436.4 0.7 1.2e-130 436.1 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRF PF01765.19 CDJ88533.1 - 0.0084 16.1 0.9 0.015 15.2 0.9 1.3 1 0 0 1 1 1 1 Ribosome recycling factor Pkinase PF00069.25 CDJ88534.1 - 1.2e-20 74.0 1.0 1.3e-20 73.9 0.1 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ88534.1 - 9.6e-15 54.6 0.0 1.2e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ88534.1 - 2.2e-05 23.4 0.0 3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDJ88534.1 - 0.00097 19.1 0.0 0.015 15.2 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Glyco_transf_29 PF00777.18 CDJ88534.1 - 0.027 13.9 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 29 (sialyltransferase) Med31 PF05669.12 CDJ88535.1 - 2.1e-35 120.6 5.7 2.7e-35 120.2 5.7 1.1 1 0 0 1 1 1 1 SOH1 PGA2 PF07543.12 CDJ88535.1 - 0.048 13.6 0.3 0.069 13.1 0.3 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 Aldedh PF00171.22 CDJ88536.1 - 3.5e-134 447.8 0.6 4.3e-134 447.5 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Lectin_leg-like PF03388.13 CDJ88537.1 - 4.9e-41 140.6 0.0 6.8e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 CDJ88537.1 - 1.1e-11 45.1 0.0 1.7e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial lectin CUT PF02376.15 CDJ88538.1 - 2.9e-31 107.5 0.0 5.7e-31 106.5 0.0 1.5 1 0 0 1 1 1 1 CUT domain Homeodomain PF00046.29 CDJ88538.1 - 6.1e-11 42.0 2.3 1.7e-10 40.6 2.3 1.9 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ88538.1 - 0.00076 19.3 0.1 0.0028 17.5 0.1 2.0 2 0 0 2 2 2 1 Homeobox KN domain Ndc1_Nup PF09531.10 CDJ88538.1 - 4.6 5.8 10.0 0.6 8.7 1.5 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Peptidase_C14 PF00656.22 CDJ88539.1 - 1.3e-14 54.7 0.0 3.4e-14 53.4 0.0 1.7 1 1 0 1 1 1 1 Caspase domain Ig_3 PF13927.6 CDJ88539.1 - 1e-05 26.0 0.1 3.1e-05 24.5 0.1 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CDJ88539.1 - 0.00024 21.4 0.2 0.00063 20.0 0.1 1.7 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 CDJ88539.1 - 0.014 15.4 0.0 0.036 14.1 0.0 1.7 1 1 0 1 1 1 0 Immunoglobulin I-set domain zf-Di19 PF05605.12 CDJ88540.1 - 2.7e-05 24.3 6.6 4.4e-05 23.7 3.2 2.3 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.7 CDJ88540.1 - 0.012 15.6 4.8 0.12 12.4 2.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 CDJ88540.1 - 0.031 13.7 7.9 0.63 9.5 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain PRP21_like_P PF12230.8 CDJ88540.1 - 0.076 12.9 0.2 5.1 6.9 0.0 2.5 2 1 1 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein Prok-RING_4 PF14447.6 CDJ88540.1 - 0.14 12.1 10.0 1 9.3 0.3 3.5 4 0 0 4 4 4 0 Prokaryotic RING finger family 4 zf_UBZ PF18439.1 CDJ88540.1 - 0.18 11.4 0.2 0.18 11.4 0.2 2.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger YhfH PF14149.6 CDJ88540.1 - 0.29 11.2 4.4 2.9 8.0 0.2 3.2 1 1 1 2 2 2 0 YhfH-like protein zf-ACC PF17848.1 CDJ88540.1 - 0.38 10.9 6.3 0.76 9.9 0.0 3.0 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain CTU2 PF10288.9 CDJ88540.1 - 0.44 10.8 3.3 1.9 8.8 3.0 2.1 2 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 PknG_rubred PF16919.5 CDJ88540.1 - 0.59 10.3 3.6 2.4 8.3 3.6 2.0 1 1 0 1 1 1 0 Protein kinase G rubredoxin domain YacG PF03884.14 CDJ88540.1 - 0.66 9.8 6.6 9.3 6.1 0.3 3.2 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG UPF0547 PF10571.9 CDJ88540.1 - 2.8 8.1 9.9 17 5.6 0.4 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Zn-ribbon_8 PF09723.10 CDJ88540.1 - 3.5 7.8 10.7 24 5.2 0.1 3.4 2 1 0 2 2 2 0 Zinc ribbon domain Mtp PF03821.16 CDJ88541.1 - 0.022 14.4 0.0 0.023 14.3 0.0 1.1 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter PAN_1 PF00024.26 CDJ88542.1 - 1e-06 28.6 20.1 0.016 15.2 7.1 3.9 3 1 0 3 3 3 3 PAN domain PAN_4 PF14295.6 CDJ88542.1 - 0.008 16.1 7.7 0.3 11.0 0.1 3.5 3 0 0 3 3 3 2 PAN domain PAN_3 PF08277.12 CDJ88542.1 - 0.01 15.6 4.0 1 9.2 0.0 3.5 3 0 0 3 3 3 0 PAN-like domain Neur_chan_LBD PF02931.23 CDJ88544.2 - 3.4e-18 65.9 0.1 4.7e-18 65.4 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ88544.2 - 0.0025 17.9 1.5 0.0039 17.3 1.5 1.7 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Pkinase PF00069.25 CDJ88549.1 - 7.3e-69 232.1 0.0 1e-68 231.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ88549.1 - 4.3e-46 157.3 0.0 8.6e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CDJ88549.1 - 1.5e-13 50.9 0.0 3.1e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 CDJ88549.1 - 1.5e-07 30.6 0.0 2.9e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDJ88549.1 - 3e-05 23.5 0.1 0.00023 20.6 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CDJ88549.1 - 0.0011 17.9 0.1 0.0018 17.3 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain DSHCT PF08148.12 CDJ88549.1 - 0.0054 16.4 0.4 0.017 14.8 0.4 1.8 1 1 0 1 1 1 1 DSHCT (NUC185) domain APH PF01636.23 CDJ88549.1 - 0.012 15.6 0.1 0.17 11.8 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Sec63 PF02889.16 CDJ88550.1 - 2.2e-159 528.4 3.6 2.2e-86 289.2 0.2 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CDJ88550.1 - 2.3e-49 167.5 0.0 5.4e-25 88.2 0.0 2.9 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 CDJ88550.1 - 2.1e-37 127.7 1.5 2.1e-37 127.7 1.5 2.4 3 0 0 3 3 2 1 N-terminal helicase PWI domain ResIII PF04851.15 CDJ88550.1 - 6e-24 84.9 0.2 1.4e-13 51.2 0.0 3.3 3 1 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CDJ88550.1 - 4.4e-08 33.5 0.0 0.012 15.9 0.0 3.1 2 0 0 2 2 2 2 AAA domain Helicase_C PF00271.31 CDJ88550.1 - 9.6e-07 29.1 0.0 2e-05 24.9 0.0 3.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 CDJ88550.1 - 6e-05 23.4 1.7 0.22 11.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 CDJ88550.1 - 0.0036 16.9 0.4 1.5 8.4 0.0 3.3 3 1 0 3 3 3 1 AAA domain PhoH PF02562.16 CDJ88550.1 - 0.0066 15.9 0.0 1.2 8.6 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein DUF603 PF04645.12 CDJ88550.1 - 0.01 15.5 0.1 0.023 14.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF603 T2SSE PF00437.20 CDJ88550.1 - 0.013 14.6 0.0 2.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_7 PF12775.7 CDJ88550.1 - 0.016 14.7 0.0 5.5 6.5 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region CDP-OH_P_transf PF01066.21 CDJ88551.1 - 3.3e-13 50.2 1.1 3.3e-13 50.2 1.1 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Branch PF02485.21 CDJ88553.1 - 5.9e-08 32.5 0.0 8.4e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme DUF3203 PF11462.8 CDJ88553.1 - 0.098 12.9 0.1 5.5 7.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3203) APH PF01636.23 CDJ88554.1 - 1.4e-17 64.4 0.0 1.9e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ88554.1 - 2.9e-06 26.3 0.1 3.8e-06 25.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 CDJ88554.1 - 0.038 13.6 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Tropomyosin_1 PF12718.7 CDJ88555.1 - 0.0032 17.6 22.6 0.06 13.5 13.0 2.3 1 1 1 2 2 2 2 Tropomyosin like HCMV_UL139 PF12507.8 CDJ88555.1 - 0.046 14.1 2.6 0.071 13.5 2.6 1.3 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein CorA PF01544.18 CDJ88555.1 - 0.047 13.0 8.8 0.18 11.1 8.8 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Exonuc_VII_L PF02601.15 CDJ88555.1 - 0.11 12.1 5.5 0.11 12.0 5.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 CDJ88555.1 - 0.14 10.1 7.3 0.14 10.1 7.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PIN_8 PF18476.1 CDJ88555.1 - 0.29 11.0 10.4 0.47 10.3 10.4 1.3 1 0 0 1 1 1 0 PIN like domain Herpes_UL6 PF01763.16 CDJ88555.1 - 0.29 9.6 6.4 0.4 9.1 6.4 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like YjbH PF06082.11 CDJ88555.1 - 0.95 8.2 3.5 1.1 8.0 3.5 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH DUF4407 PF14362.6 CDJ88555.1 - 1.3 8.4 7.5 1.5 8.1 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 CDJ88555.1 - 2.3 7.2 11.1 3.2 6.8 11.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ICA69 PF04629.14 CDJ88555.1 - 3.3 7.9 11.4 4.4 7.6 11.4 1.2 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain HalX PF08663.10 CDJ88555.1 - 3.4 8.0 14.6 2.6 8.4 0.1 3.2 2 1 1 3 3 3 0 HalX domain TBCA PF02970.16 CDJ88555.1 - 3.5 8.0 16.9 0.26 11.6 9.0 2.8 1 1 1 2 2 2 0 Tubulin binding cofactor A FAM76 PF16046.5 CDJ88555.1 - 3.8 6.8 16.0 1.4 8.2 2.6 2.1 1 1 1 2 2 2 0 FAM76 protein Phage_GP20 PF06810.11 CDJ88555.1 - 3.9 7.3 14.7 0.23 11.2 5.8 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 Spc7 PF08317.11 CDJ88555.1 - 4.5 6.1 19.5 9.5 5.0 19.5 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.10 CDJ88555.1 - 5 7.3 14.4 4.7 7.4 5.2 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.20 CDJ88555.1 - 6.7 6.7 18.7 0.92 9.5 8.4 3.0 3 1 0 3 3 3 0 Prefoldin subunit DUF4094 PF13334.6 CDJ88555.1 - 7.9 7.0 11.5 11 6.5 5.3 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4094) DUF3450 PF11932.8 CDJ88555.1 - 9.3 5.5 17.4 12 5.2 15.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) WD40 PF00400.32 CDJ88556.1 - 1.1e-49 165.4 26.2 1.4e-07 32.0 0.1 10.5 10 0 0 10 10 10 9 WD domain, G-beta repeat Utp12 PF04003.12 CDJ88556.1 - 6.2e-18 65.1 0.2 1.1e-17 64.3 0.2 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 CDJ88556.1 - 9.4e-14 51.5 2.5 0.012 15.9 0.0 8.3 2 2 6 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ88556.1 - 8.8e-05 21.6 0.7 3.1 6.7 0.1 5.3 2 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CDJ88556.1 - 0.0012 18.2 0.0 6.9 5.9 0.0 4.4 3 1 0 3 3 3 1 WD40-like domain Cytochrom_D1 PF02239.16 CDJ88556.1 - 0.012 14.2 0.1 0.4 9.1 0.1 3.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain RVT_1 PF00078.27 CDJ88559.1 - 1.1e-18 67.5 0.0 1.2e-18 67.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C1 PF00112.23 CDJ88560.1 - 1.9e-66 224.3 6.1 2.3e-66 224.0 6.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C39_2 PF13529.6 CDJ88560.1 - 0.042 14.4 0.0 0.082 13.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase_C39 like family Peptidase_C1_2 PF03051.15 CDJ88560.1 - 0.34 9.6 4.6 0.13 11.0 0.6 1.9 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ88561.1 - 4.9e-67 226.2 6.6 6.1e-67 225.9 6.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ88561.1 - 0.029 13.2 0.3 0.029 13.2 0.3 1.8 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ88562.1 - 2.1e-64 217.6 9.1 2.6e-64 217.3 9.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Asparaginase_C PF17763.1 CDJ88562.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain Peptidase_C1_2 PF03051.15 CDJ88562.1 - 0.5 9.1 3.6 0.31 9.8 0.7 1.8 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ88563.1 - 9e-66 222.1 6.0 1.1e-65 221.8 6.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ88563.1 - 0.54 9.0 5.5 0.095 11.5 1.0 1.8 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ88564.1 - 1.3e-61 208.5 6.1 2.8e-34 119.1 0.1 2.3 2 0 0 2 2 2 2 Papain family cysteine protease RVT_1 PF00078.27 CDJ88564.1 - 8e-10 38.6 0.0 2e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C1_2 PF03051.15 CDJ88564.1 - 0.86 8.3 3.9 0.55 9.0 0.7 1.9 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ88565.1 - 2.1e-37 129.3 14.9 1.2e-20 74.6 4.2 2.1 1 1 1 2 2 2 2 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ88565.1 - 0.19 10.5 2.4 0.31 9.8 0.2 1.9 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ88566.1 - 7.7e-28 98.1 6.6 9.5e-28 97.8 6.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease DPBB_1 PF03330.18 CDJ88566.1 - 2.4 8.5 5.2 0.65 10.3 1.7 1.8 2 0 0 2 2 2 0 Lytic transglycolase Peptidase_C1 PF00112.23 CDJ88568.1 - 9e-67 225.3 2.6 1.1e-66 225.0 2.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ88568.1 - 0.17 10.6 1.4 0.45 9.2 0.3 1.8 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ88569.1 - 6.3e-59 199.7 4.2 8.3e-59 199.3 4.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ88569.1 - 0.014 14.2 1.6 0.026 13.3 0.3 1.9 2 0 0 2 2 2 0 Peptidase C1-like family Collagen PF01391.18 CDJ88570.1 - 1.3e-25 88.9 103.8 7.4e-10 38.4 39.6 3.8 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ88570.1 - 9.8e-10 38.3 0.1 1.2e-09 38.0 0.1 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain 7tm_1 PF00001.21 CDJ88571.1 - 3.7e-38 131.4 17.2 4.9e-38 131.0 17.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 CDJ88571.1 - 0.00089 19.1 5.4 0.00089 19.1 5.4 1.5 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 CDJ88571.1 - 0.0031 17.2 13.5 0.0056 16.4 10.5 2.5 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx zf-C2H2 PF00096.26 CDJ88572.1 - 3e-21 74.6 30.0 1.5e-05 25.1 0.7 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ88572.1 - 2.2e-19 69.0 31.7 3.9e-08 33.4 0.4 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDJ88572.1 - 3e-14 52.5 24.9 0.00065 20.3 0.6 5.6 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ88572.1 - 6.1e-05 23.2 17.0 0.011 16.0 0.2 4.8 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 CDJ88572.1 - 0.00048 19.8 19.8 0.052 13.3 1.4 5.1 4 1 0 4 4 4 3 C2H2-type zinc-finger domain zf_ZIC PF18366.1 CDJ88572.1 - 0.0057 16.7 0.2 0.0057 16.7 0.2 4.6 4 1 1 5 5 5 1 Zic proteins zinc finger domain zf-C2H2_8 PF15909.5 CDJ88572.1 - 0.013 15.8 12.1 0.2 11.9 2.4 2.9 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-met PF12874.7 CDJ88572.1 - 0.015 15.7 13.1 7.2 7.1 0.3 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DivIC PF04977.15 CDJ88572.1 - 0.14 12.0 0.5 0.23 11.3 0.5 1.4 1 0 0 1 1 1 0 Septum formation initiator zf-C2H2_aberr PF17017.5 CDJ88572.1 - 0.16 12.1 11.9 2.2 8.4 1.7 3.3 2 1 1 3 3 3 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 CDJ88572.1 - 0.35 10.7 4.4 17 5.3 0.6 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type CHORD PF04968.12 CDJ88572.1 - 3.6 8.4 17.3 3 8.6 0.9 4.1 2 1 2 4 4 4 0 CHORD PAM2 PF07145.15 CDJ88574.1 - 0.0058 16.2 0.6 0.02 14.6 0.6 1.9 1 0 0 1 1 1 1 Ataxin-2 C-terminal region F-box PF00646.33 CDJ88575.1 - 3.9e-07 29.8 0.3 1.1e-06 28.4 0.3 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDJ88575.1 - 1.6e-05 24.7 2.0 4.4e-05 23.3 0.5 2.5 2 0 0 2 2 2 1 F-box-like Tubulin PF00091.25 CDJ88576.1 - 1.2e-66 224.7 0.0 1.6e-66 224.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDJ88576.1 - 9.6e-49 164.7 0.0 1.5e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CDJ88576.1 - 0.0015 18.2 0.0 0.0042 16.8 0.0 1.8 1 0 0 1 1 1 1 Tubulin domain Na_H_Exchanger PF00999.21 CDJ88577.1 - 3.6e-81 272.9 45.7 4.3e-81 272.6 45.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Str_synth PF03088.16 CDJ88578.1 - 9.9e-17 60.9 0.0 1.2e-15 57.4 0.0 2.9 4 0 0 4 4 4 1 Strictosidine synthase DUF3330 PF11809.8 CDJ88579.1 - 0.03 14.4 0.1 0.058 13.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) Peptidase_M1_N PF17900.1 CDJ88582.1 - 4.1e-09 36.9 0.0 6.2e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain SR-25 PF10500.9 CDJ88582.1 - 8.9 5.9 12.5 12 5.4 12.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ABC_membrane PF00664.23 CDJ88583.1 - 4.1e-61 207.0 8.1 4.1e-61 207.0 8.1 2.1 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ88583.1 - 5.3e-34 117.7 0.0 1.1e-33 116.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CDJ88583.1 - 6.4e-09 35.6 0.0 5.3e-08 32.6 0.0 2.0 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDJ88583.1 - 0.001 19.5 0.0 0.015 15.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CDJ88583.1 - 0.0017 18.3 0.0 0.0039 17.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 CDJ88583.1 - 0.022 15.1 0.2 0.16 12.2 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CDJ88583.1 - 0.028 14.1 0.1 0.11 12.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CDJ88583.1 - 0.067 12.9 0.1 0.41 10.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 CDJ88583.1 - 0.1 11.8 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AA_permease_N PF08403.10 CDJ88583.1 - 0.15 11.6 0.0 0.41 10.2 0.0 1.6 1 0 0 1 1 1 0 Amino acid permease N-terminal TraL PF07178.11 CDJ88583.1 - 4.9 7.7 5.7 4 8.0 0.1 3.2 3 0 0 3 3 3 0 TraL protein DUF4191 PF13829.6 CDJ88583.1 - 5.4 6.3 5.6 0.89 8.8 1.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Globin PF00042.22 CDJ88584.1 - 1.1e-09 38.8 0.0 1.7e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Globin Ku_PK_bind PF08785.11 CDJ88584.1 - 0.055 13.6 0.1 0.11 12.7 0.1 1.5 1 1 0 1 1 1 0 Ku C terminal domain like ABC_membrane PF00664.23 CDJ88585.1 - 7e-39 134.1 7.4 1e-38 133.6 7.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ88585.1 - 1.2e-30 106.9 0.0 1.2e-30 106.9 0.0 2.8 3 1 0 3 3 3 1 ABC transporter SMC_N PF02463.19 CDJ88585.1 - 4.9e-08 32.7 0.0 7.4e-06 25.6 0.0 2.6 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CDJ88585.1 - 0.0026 17.6 1.0 0.87 9.3 0.2 3.0 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 CDJ88585.1 - 0.0095 16.0 0.1 0.04 14.0 0.1 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CDJ88585.1 - 0.078 13.2 0.9 1.7 8.9 0.9 2.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CDJ88585.1 - 0.14 12.5 1.2 0.54 10.6 1.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain ACT_7 PF13840.6 CDJ88586.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 ACT domain Na_H_Exchanger PF00999.21 CDJ88588.1 - 1.7e-76 257.5 39.3 2.2e-76 257.1 39.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Peptidase_M1_N PF17900.1 CDJ88589.1 - 1.1e-16 61.6 0.6 1.4e-16 61.3 0.6 1.1 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Amnionless PF14828.6 CDJ88590.1 - 0.014 14.2 1.7 0.021 13.7 1.7 1.2 1 0 0 1 1 1 0 Amnionless CD34_antigen PF06365.12 CDJ88590.1 - 0.033 13.8 0.9 0.056 13.0 0.9 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family SIT PF15330.6 CDJ88590.1 - 0.087 13.3 0.6 0.18 12.3 0.6 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT RIFIN PF02009.16 CDJ88590.1 - 0.11 12.4 0.3 0.18 11.7 0.3 1.2 1 0 0 1 1 1 0 Rifin PSD4 PF07631.11 CDJ88591.1 - 0.11 13.0 0.1 0.7 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) Innexin PF00876.18 CDJ88592.1 - 8.1e-106 354.3 18.4 1.7e-102 343.4 14.5 2.0 2 0 0 2 2 2 2 Innexin DUF2664 PF10867.8 CDJ88592.1 - 0.014 15.8 0.1 1.1 9.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2664) Lactonase PF10282.9 CDJ88592.1 - 0.023 13.9 0.0 4.3 6.5 0.0 2.1 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Alg14 PF08660.11 CDJ88592.1 - 0.042 13.8 1.1 1.4 8.8 0.2 2.5 2 0 0 2 2 2 0 Oligosaccharide biosynthesis protein Alg14 like Radial_spoke_3 PF06098.11 CDJ88592.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 Ribosomal_L44 PF00935.19 CDJ88592.1 - 0.27 11.8 0.3 45 4.6 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L44 Innexin PF00876.18 CDJ88593.1 - 1.1e-121 406.4 8.9 1.3e-121 406.2 8.9 1.0 1 0 0 1 1 1 1 Innexin EstA_Ig_like PF18435.1 CDJ88594.1 - 0.06 13.5 0.3 0.1 12.8 0.3 1.3 1 0 0 1 1 1 0 Esterase Ig-like N-terminal domain Hamartin PF04388.12 CDJ88594.1 - 0.099 11.3 8.1 0.12 11.0 8.1 1.1 1 0 0 1 1 1 0 Hamartin protein zf-CCCH PF00642.24 CDJ88595.1 - 5.3e-18 64.5 5.3 5e-10 39.0 0.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ88595.1 - 2.2e-11 43.4 7.0 8.9e-06 25.6 1.0 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 CDJ88595.1 - 3.9e-11 42.5 4.4 9.5e-05 22.1 0.2 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CDJ88595.1 - 6.9e-06 26.3 5.4 0.021 15.3 0.6 2.6 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CDJ88595.1 - 0.019 15.7 5.7 1.9 9.2 0.6 2.4 2 0 0 2 2 2 0 Torus domain Protocadherin PF08374.11 CDJ88596.1 - 0.003 17.6 3.2 0.14 12.1 0.0 2.2 2 0 0 2 2 2 1 Protocadherin SID-1_RNA_chan PF13965.6 CDJ88596.1 - 0.019 13.4 0.2 0.024 13.1 0.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TNFR_16_TM PF18422.1 CDJ88596.1 - 0.027 14.4 1.0 0.063 13.2 1.0 1.5 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF2207 PF09972.9 CDJ88596.1 - 0.029 13.1 0.0 0.053 12.3 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EphA2_TM PF14575.6 CDJ88596.1 - 0.039 14.8 0.4 0.25 12.2 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Glycophorin_A PF01102.18 CDJ88596.1 - 0.057 13.7 5.4 0.72 10.1 0.0 2.7 2 1 1 3 3 3 0 Glycophorin A MIG-14_Wnt-bd PF06664.12 CDJ88596.1 - 0.063 12.5 0.0 0.091 12.0 0.0 1.1 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion 7TM_GPCR_Srw PF10324.9 CDJ88596.1 - 0.092 12.0 0.0 0.092 12.0 0.0 1.4 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw Orf78 PF06024.12 CDJ88596.1 - 0.12 12.7 1.4 0.22 11.8 0.1 1.9 2 0 0 2 2 2 0 Orf78 (ac78) TMEM154 PF15102.6 CDJ88596.1 - 0.12 12.3 0.1 0.12 12.3 0.1 2.5 2 1 0 2 2 1 0 TMEM154 protein family OAD_gamma PF04277.13 CDJ88596.1 - 0.25 12.0 1.7 7.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Kelch_1 PF01344.25 CDJ88597.1 - 2e-59 196.9 9.4 8.8e-12 44.4 0.1 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CDJ88597.1 - 2.2e-35 119.8 0.8 7.7e-07 29.2 0.0 7.0 3 2 3 6 6 6 6 Kelch motif Kelch_4 PF13418.6 CDJ88597.1 - 3.6e-18 65.3 3.5 0.00012 22.0 0.1 6.7 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 CDJ88597.1 - 7.3e-17 60.6 13.0 0.00038 20.3 0.1 6.8 7 1 0 7 7 7 4 Kelch motif Kelch_3 PF13415.6 CDJ88597.1 - 5.3e-13 48.9 4.9 0.11 12.8 0.0 6.7 7 0 0 7 7 7 4 Galactose oxidase, central domain BACK PF07707.15 CDJ88597.1 - 9.6e-10 38.5 0.1 1.7e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 CDJ88597.1 - 1.9e-06 27.7 4.2 0.58 10.2 0.1 6.0 6 0 0 6 6 6 2 Kelch motif PQQ_3 PF13570.6 CDJ88597.1 - 0.029 14.9 7.3 0.94 10.1 0.1 4.9 6 0 0 6 6 6 0 PQQ-like domain Kelch_1 PF01344.25 CDJ88598.1 - 6.8e-41 137.6 14.9 4.3e-11 42.2 0.0 7.9 7 1 0 7 7 7 7 Kelch motif Kelch_6 PF13964.6 CDJ88598.1 - 1.5e-24 85.4 3.3 0.00013 22.1 0.0 6.2 2 2 3 5 5 5 5 Kelch motif BACK PF07707.15 CDJ88598.1 - 6.8e-18 64.7 2.6 1.2e-17 63.9 0.4 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 CDJ88598.1 - 5.2e-12 45.2 5.0 0.045 13.7 0.0 5.9 5 1 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 CDJ88598.1 - 1.2e-10 41.2 5.2 0.087 12.8 0.0 5.7 5 2 0 5 5 5 4 Galactose oxidase, central domain BTB PF00651.31 CDJ88598.1 - 1.8e-09 37.8 0.3 6.9e-09 35.9 0.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.6 CDJ88598.1 - 2.3e-06 27.7 12.9 0.25 11.7 0.2 6.7 6 1 0 6 6 6 1 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ88598.1 - 0.00014 21.8 0.3 5.6 7.1 0.1 5.1 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.25 CDJ88599.1 - 2.8e-64 212.5 13.8 8.5e-13 47.7 0.6 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CDJ88599.1 - 6.9e-41 137.2 7.5 1.2e-07 31.7 0.1 6.3 2 2 4 6 6 6 6 Kelch motif Kelch_2 PF07646.15 CDJ88599.1 - 9.7e-22 76.1 8.9 1.1e-05 25.2 0.3 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 CDJ88599.1 - 8e-18 64.2 1.5 0.037 14.0 0.1 6.0 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ88599.1 - 3.9e-16 58.9 4.0 0.041 14.2 0.0 5.5 5 0 0 5 5 5 5 Galactose oxidase, central domain BACK PF07707.15 CDJ88599.1 - 1e-08 35.2 0.0 1.7e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 CDJ88599.1 - 0.0028 17.6 4.1 30 4.7 0.0 4.8 5 0 0 5 5 5 0 Kelch motif DUF2963 PF11178.8 CDJ88599.1 - 0.13 11.9 0.0 29 4.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2963) VWA PF00092.28 CDJ88600.1 - 9.9e-16 58.5 2.4 4.3e-12 46.6 0.1 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain Lectin_C PF00059.21 CDJ88600.1 - 2.7e-13 50.6 2.2 2.9e-13 50.5 0.6 1.9 2 0 0 2 2 2 1 Lectin C-type domain VWA_2 PF13519.6 CDJ88600.1 - 9.9e-08 32.6 0.5 0.001 19.7 0.1 2.6 2 0 0 2 2 2 2 von Willebrand factor type A domain HhH-GPD PF00730.25 CDJ88601.1 - 1.1e-19 70.8 0.0 4.7e-19 68.8 0.0 2.0 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CDJ88601.1 - 1.3e-09 37.4 0.0 3.5e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_8 PF14716.6 CDJ88601.1 - 0.084 13.3 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain N36 PF11438.8 CDJ88601.1 - 0.12 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 36-mer N-terminal peptide of the N protein (N36) FPP PF05911.11 CDJ88602.1 - 0.0016 16.8 57.6 0.0016 16.8 57.6 3.4 1 1 2 3 3 3 1 Filament-like plant protein, long coiled-coil Ldl_recept_a PF00057.18 CDJ88603.1 - 3.7e-52 174.2 136.0 2.4e-09 37.3 7.2 9.7 9 1 0 9 9 9 8 Low-density lipoprotein receptor domain class A Mt_ATP-synt_B PF05405.14 CDJ88604.1 - 2.6e-33 115.0 2.6 3.2e-33 114.7 2.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) YabA PF06156.13 CDJ88604.1 - 0.43 11.2 2.6 0.81 10.4 2.6 1.5 1 0 0 1 1 1 0 Initiation control protein YabA 7tm_1 PF00001.21 CDJ88605.1 - 2.2e-18 66.6 13.7 2.9e-09 36.7 8.5 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) DUF420 PF04238.12 CDJ88605.1 - 0.055 13.8 0.6 0.055 13.8 0.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF420) 7TM_GPCR_Srw PF10324.9 CDJ88605.1 - 0.39 9.9 11.4 0.045 13.0 2.6 2.4 2 1 1 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srw DUF1768 PF08719.11 CDJ88606.1 - 6.8e-21 75.2 1.9 1.1e-20 74.5 1.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Glyco_hydro_47 PF01532.20 CDJ88607.1 - 1.8e-154 515.1 0.6 2.1e-154 514.8 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Svs_4_5_6 PF17381.2 CDJ88607.1 - 0.17 12.9 0.3 0.36 11.8 0.3 1.5 1 0 0 1 1 1 0 Seminal vesicle secretory proteins 4/5/6 ASD1 PF08688.10 CDJ88607.1 - 0.51 10.7 2.3 28 5.0 0.0 2.3 2 0 0 2 2 2 0 Apx/Shroom domain ASD1 DUF4807 PF16065.5 CDJ88608.1 - 1.3e-33 115.4 1.1 1.4e-33 115.2 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4807) PseudoU_synth_2 PF00849.22 CDJ88609.1 - 3.9e-12 46.5 0.5 7.6e-12 45.6 0.0 1.7 2 0 0 2 2 2 1 RNA pseudouridylate synthase CBS PF00571.28 CDJ88613.1 - 1.2e-32 112.2 5.4 7.9e-09 35.8 0.5 4.4 4 0 0 4 4 4 4 CBS domain Meis_PKNOX_N PF16493.5 CDJ88615.1 - 5.2e-17 62.0 0.2 8e-17 61.4 0.2 1.3 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 Glyco_hydro_56 PF01630.18 CDJ88616.1 - 1e-17 64.2 0.6 1.1e-17 64.1 0.6 1.0 1 0 0 1 1 1 1 Hyaluronidase Glyco_hydro_56 PF01630.18 CDJ88617.1 - 3.5e-23 82.2 0.0 4.1e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 Hyaluronidase Glyco_hydro_56 PF01630.18 CDJ88618.1 - 7.4e-30 104.1 0.5 1.8e-14 53.5 0.0 2.1 1 1 1 2 2 2 2 Hyaluronidase ATP-grasp_2 PF08442.10 CDJ88619.1 - 4.4e-39 134.1 0.3 4.6e-38 130.8 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 CDJ88619.1 - 3.9e-27 95.0 2.3 6e-27 94.4 2.3 1.3 1 0 0 1 1 1 1 CoA-ligase Anoctamin PF04547.12 CDJ88620.1 - 1.3e-138 462.6 17.7 1.7e-138 462.2 17.7 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 CDJ88620.1 - 1.4e-54 185.3 0.0 2.1e-54 184.6 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Claudin_2 PF13903.6 CDJ88620.1 - 0.054 13.3 3.3 0.056 13.2 0.7 2.3 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Renin_r PF07850.14 CDJ88620.1 - 0.62 10.7 1.9 6.8 7.4 0.0 3.2 3 0 0 3 3 3 0 Renin receptor-like protein DUF1282 PF06930.12 CDJ88620.1 - 1.2 8.9 9.4 0.041 13.7 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) DUF5453 PF17534.2 CDJ88620.1 - 8.3 6.3 9.3 0.42 10.5 2.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5453) Solute_trans_a PF03619.16 CDJ88621.1 - 1.4e-10 41.2 13.7 4.2e-06 26.5 0.7 2.0 1 1 1 2 2 2 2 Organic solute transporter Ostalpha 7tm_1 PF00001.21 CDJ88622.1 - 2.2e-45 155.1 21.2 8.3e-45 153.2 21.2 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 CDJ88622.1 - 2.8e-07 30.6 16.2 5.5e-07 29.6 16.2 1.4 1 1 0 1 1 1 1 Olfactory receptor DUF898 PF05987.13 CDJ88622.1 - 0.0001 21.5 1.6 0.0001 21.5 1.6 1.6 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF898) EF-hand_7 PF13499.6 CDJ88623.1 - 0.00023 21.5 0.5 0.0069 16.8 0.4 2.7 2 1 0 2 2 2 1 EF-hand domain pair EF_assoc_2 PF08356.12 CDJ88623.1 - 0.00037 20.4 0.0 0.00076 19.4 0.0 1.4 1 0 0 1 1 1 1 EF hand associated EF-hand_1 PF00036.32 CDJ88623.1 - 0.00075 18.9 2.4 0.19 11.4 0.3 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CDJ88623.1 - 0.0019 18.0 1.3 0.12 12.4 0.3 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 CDJ88623.1 - 0.15 12.0 1.7 0.84 9.5 0.4 2.7 3 0 0 3 3 3 0 EF-hand domain pair TFIID-31kDa PF02291.15 CDJ88627.1 - 2.9e-29 101.6 0.0 3.9e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 CDJ88627.1 - 0.16 12.4 0.1 0.27 11.7 0.1 1.2 1 0 0 1 1 1 0 CENP-S protein EF-hand_1 PF00036.32 CDJ88628.1 - 1.7e-10 39.7 0.6 0.00024 20.4 0.0 3.8 4 1 1 5 5 5 2 EF hand EF-hand_6 PF13405.6 CDJ88628.1 - 4.7e-10 38.6 0.2 0.0014 18.4 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CDJ88628.1 - 4.9e-10 39.7 0.2 0.0015 18.9 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ88628.1 - 3.4e-06 26.8 0.9 0.088 12.7 0.0 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 CDJ88628.1 - 0.00045 20.5 0.0 0.32 11.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.13 CDJ88628.1 - 0.024 14.6 0.0 3.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF3349 PF11829.8 CDJ88628.1 - 0.11 13.3 0.0 12 6.8 0.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3349) EF-hand_14 PF17959.1 CDJ88628.1 - 0.15 12.4 0.0 13 6.2 0.0 2.5 1 1 1 2 2 2 0 EF-hand domain DUF2267 PF10025.9 CDJ88628.1 - 0.2 12.0 0.8 1.3 9.4 0.3 2.2 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) GPHH PF16905.5 CDJ88628.1 - 0.22 11.3 0.0 3.4 7.5 0.0 2.2 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated Hus1 PF04005.12 CDJ88629.1 - 1.2e-28 100.1 0.2 1.8e-28 99.5 0.2 1.3 1 0 0 1 1 1 1 Hus1-like protein COG7 PF10191.9 CDJ88629.1 - 0.046 12.0 0.1 0.062 11.5 0.1 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) Rad51 PF08423.11 CDJ88630.1 - 1.3e-17 64.0 0.0 1.5e-17 63.7 0.0 1.0 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 CDJ88630.1 - 7.4e-05 22.4 1.2 0.0001 21.9 1.2 1.2 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CDJ88630.1 - 0.0081 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain LRR_8 PF13855.6 CDJ88631.1 - 6.7e-32 109.0 47.2 2.2e-09 37.0 5.9 3.7 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 CDJ88631.1 - 9e-18 64.1 20.4 1.1e-06 28.8 3.5 4.5 2 2 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDJ88631.1 - 1.2e-10 40.4 15.6 1.4 9.8 0.0 7.9 8 0 0 8 8 8 5 Leucine Rich Repeat LRR_6 PF13516.6 CDJ88631.1 - 0.00012 21.8 20.0 3.5 7.9 0.2 6.5 6 0 0 6 6 6 3 Leucine Rich repeat RsmF_methylt_CI PF17126.5 CDJ88631.1 - 0.017 15.1 0.1 80 3.4 0.0 4.1 2 2 2 4 4 4 0 RsmF rRNA methyltransferase first C-terminal domain TPR_1 PF00515.28 CDJ88632.1 - 0.0012 18.6 1.2 0.0052 16.5 0.2 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ88632.1 - 0.018 15.1 0.2 0.11 12.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ88632.1 - 0.03 14.5 0.9 0.07 13.4 0.4 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 ANAPC8 PF04049.13 CDJ88632.1 - 0.13 12.3 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Anaphase promoting complex subunit 8 / Cdc23 RT_RNaseH_2 PF17919.1 CDJ88633.1 - 2.8e-34 117.2 0.0 6.7e-34 115.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ88633.1 - 1.8e-32 111.7 0.0 3.7e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ88633.1 - 6.3e-21 74.9 0.0 1.3e-20 73.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ88633.1 - 5.8e-14 51.9 0.1 1.3e-13 50.8 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP PF00077.20 CDJ88633.1 - 6.6e-05 23.2 0.0 0.00017 21.8 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ88633.1 - 7.6e-05 23.3 0.0 0.00017 22.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ88633.1 - 0.00038 21.0 0.0 0.00084 19.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 CDJ88633.1 - 0.02 15.1 0.1 0.055 13.7 0.0 1.8 2 0 0 2 2 2 0 H2C2 zinc finger Pkinase_Tyr PF07714.17 CDJ88634.1 - 3.9e-79 265.6 0.0 6.7e-79 264.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ88634.1 - 1.1e-36 126.5 0.0 1.7e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Gly_rich PF12810.7 CDJ88634.1 - 1.6e-16 61.0 11.5 2.6e-16 60.3 11.5 1.2 1 0 0 1 1 1 1 Glycine rich protein MAM PF00629.23 CDJ88634.1 - 7.8e-10 38.9 0.0 1.9e-06 27.9 0.0 2.4 2 0 0 2 2 2 2 MAM domain, meprin/A5/mu Kinase-like PF14531.6 CDJ88634.1 - 0.21 10.8 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Ldl_recept_a PF00057.18 CDJ88634.1 - 0.66 10.2 8.8 2.5 8.4 8.8 2.1 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A PA_decarbox PF05870.11 CDJ88635.1 - 0.0014 18.2 0.0 0.0056 16.3 0.0 1.8 2 0 0 2 2 2 1 Phenolic acid decarboxylase (PAD) Pkinase PF00069.25 CDJ88636.1 - 4.6e-15 55.7 0.0 5.5e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ88636.1 - 1.4e-09 37.6 0.0 2.8e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ88636.1 - 0.004 17.1 0.0 3.6 7.5 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ88636.1 - 0.012 14.4 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase MMS1_N PF10433.9 CDJ88637.1 - 1.1e-38 133.1 3.1 3.9e-20 71.9 0.0 3.6 3 1 1 4 4 4 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CDJ88637.1 - 0.00011 21.7 0.3 0.00049 19.5 0.0 2.3 4 0 0 4 4 4 1 CPSF A subunit region Raf1_HTH PF18579.1 CDJ88638.1 - 0.038 13.7 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain Beta-lactamase PF00144.24 CDJ88639.1 - 8.9e-65 219.1 0.0 1.1e-64 218.8 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase YoaP PF14268.6 CDJ88639.1 - 0.11 12.0 0.0 0.98 9.0 0.0 2.4 2 0 0 2 2 2 0 YoaP-like Beta-lactamase PF00144.24 CDJ88640.1 - 1.3e-63 215.3 0.0 1.6e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase YoaP PF14268.6 CDJ88640.1 - 0.12 11.9 0.0 0.93 9.1 0.0 2.4 2 0 0 2 2 2 0 YoaP-like zf-C2H2 PF00096.26 CDJ88641.1 - 0.0019 18.6 4.7 0.0019 18.6 4.7 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ88641.1 - 0.038 14.8 10.7 0.067 14.1 4.8 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger BolA PF01722.18 CDJ88641.1 - 0.046 14.0 0.0 0.064 13.5 0.0 1.3 1 0 0 1 1 1 0 BolA-like protein zf-H2C2_2 PF13465.6 CDJ88641.1 - 0.31 11.5 7.6 2.1 8.9 0.9 2.5 2 0 0 2 2 2 0 Zinc-finger double domain EGF_CA PF07645.15 CDJ88641.1 - 0.55 10.5 7.2 4 7.7 0.3 3.1 3 0 0 3 3 3 0 Calcium-binding EGF domain DUF629 PF04780.12 CDJ88641.1 - 2.8 6.3 5.8 4.1 5.8 3.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-AN1 PF01428.16 CDJ88641.1 - 4.3 7.6 9.3 1.3 9.2 3.0 2.3 1 1 1 2 2 2 0 AN1-like Zinc finger zf-met PF12874.7 CDJ88641.1 - 7.5 7.1 12.5 0.88 10.0 2.7 2.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Apo-CII PF05355.11 CDJ88644.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.8 1 1 0 1 1 1 0 Apolipoprotein C-II ShK PF01549.24 CDJ88646.1 - 2.7e-07 31.0 6.6 5.1e-07 30.1 5.8 1.8 2 0 0 2 2 2 1 ShK domain-like TB2_DP1_HVA22 PF03134.19 CDJ88647.1 - 8e-05 22.5 0.1 0.00012 21.9 0.1 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family HSP20 PF00011.21 CDJ88648.1 - 1.1e-16 60.8 0.0 1.7e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ88648.1 - 0.068 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 HSP20-like domain found in ArsA RNA_pol_Rpb1_1 PF04997.12 CDJ88649.1 - 5.8e-84 282.1 0.1 1.1e-83 281.1 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 CDJ88649.1 - 1.6e-82 276.9 1.3 2.5e-82 276.3 1.3 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CDJ88649.1 - 2e-74 249.3 0.1 4.1e-74 248.3 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CDJ88649.1 - 1.5e-39 135.5 0.0 1.9e-38 131.9 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CDJ88649.1 - 6.3e-30 103.3 0.0 1.6e-29 102.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Ets PF00178.22 CDJ88650.1 - 3.7e-24 85.0 0.6 6.8e-24 84.1 0.6 1.5 1 0 0 1 1 1 1 Ets-domain SAP25 PF15476.6 CDJ88650.1 - 0.018 14.7 0.4 0.044 13.4 0.4 1.6 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP25 ubiquitin PF00240.23 CDJ88651.1 - 1.8e-34 117.3 0.4 2.6e-34 116.8 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CDJ88651.1 - 1.1e-30 105.3 11.0 1.6e-30 104.7 11.0 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CDJ88651.1 - 2.2e-16 59.4 1.8 2.6e-16 59.2 0.5 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDJ88651.1 - 1.5e-05 25.4 0.1 6.5e-05 23.3 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 CDJ88651.1 - 0.0029 17.9 0.1 0.0053 17.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDJ88651.1 - 0.0047 17.0 0.1 0.0091 16.1 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 CDJ88651.1 - 0.0056 16.6 0.0 0.0073 16.2 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 CDJ88651.1 - 0.015 15.3 1.2 4.2 7.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 CDJ88651.1 - 0.023 15.3 0.1 0.029 14.9 0.1 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain FRG1 PF06229.12 CDJ88652.1 - 7.8e-63 211.6 0.6 1.1e-62 211.2 0.6 1.2 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 CDJ88652.1 - 3.5e-07 30.4 0.0 2.5e-06 27.7 0.0 2.3 2 1 0 2 2 2 1 Fascin domain DUF1754 PF08555.10 CDJ88652.1 - 0.0026 18.5 4.9 0.0026 18.5 4.9 2.2 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Not1 PF04054.15 CDJ88653.1 - 3.4e-122 407.9 1.2 3.4e-122 407.9 1.2 1.8 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 DUF3819 PF12842.7 CDJ88653.1 - 3.5e-41 140.5 6.2 9.2e-41 139.2 6.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_CAF1_bind PF16415.5 CDJ88653.1 - 3.5e-30 105.1 1.5 7.5e-30 104.0 0.6 2.1 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain BAR_3 PF16746.5 CDJ88653.1 - 0.031 14.0 0.4 2.8 7.6 0.0 2.5 2 0 0 2 2 2 0 BAR domain of APPL family CNOT1_TTP_bind PF16417.5 CDJ88654.1 - 8.6e-53 178.3 0.1 2.3e-52 177.0 0.1 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_CAF1_bind PF16415.5 CDJ88654.1 - 8e-42 143.1 0.2 1.5e-41 142.2 0.2 1.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_HEAT PF16418.5 CDJ88654.1 - 9.9e-23 80.9 0.5 4.5e-22 78.8 0.1 2.3 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Sec10 PF07393.11 CDJ88654.1 - 0.087 11.2 0.0 0.19 10.1 0.0 1.5 1 0 0 1 1 1 0 Exocyst complex component Sec10 RPN6_N PF18055.1 CDJ88656.1 - 8.5e-28 97.1 0.4 2.3e-27 95.7 0.4 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 CDJ88656.1 - 2.2e-16 60.3 0.1 7.1e-16 58.6 0.0 2.0 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 CDJ88656.1 - 6.9e-13 48.1 0.1 1.5e-12 47.0 0.1 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain DUF5397 PF17375.2 CDJ88656.1 - 0.032 13.9 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5397) Vps53_N PF04100.12 CDJ88656.1 - 0.037 13.0 0.2 0.11 11.5 0.1 1.9 2 0 0 2 2 2 0 Vps53-like, N-terminal RIO1 PF01163.22 CDJ88657.1 - 6.7e-61 205.2 0.0 1.8e-60 203.8 0.0 1.7 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 CDJ88657.1 - 9.7e-06 25.1 0.0 2.3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 CDJ88657.1 - 0.00059 19.8 0.2 0.013 15.5 0.0 3.0 2 2 1 4 4 4 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ88657.1 - 0.013 14.3 0.1 0.013 14.3 0.1 2.1 2 1 0 2 2 2 0 Fungal protein kinase Choline_kinase PF01633.20 CDJ88657.1 - 0.21 11.1 3.3 1.3 8.6 0.8 3.1 2 1 1 3 3 3 0 Choline/ethanolamine kinase PAN_1 PF00024.26 CDJ88658.1 - 5.9e-06 26.2 0.7 8.1e-06 25.7 0.7 1.2 1 0 0 1 1 1 1 PAN domain Neur_chan_LBD PF02931.23 CDJ88660.1 - 6.1e-36 123.9 0.1 8.7e-36 123.4 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ88660.1 - 2.6e-29 103.0 1.3 1.6e-24 87.3 0.1 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF1088 PF06469.11 CDJ88661.1 - 1.2e-50 171.5 4.6 2.4e-50 170.5 4.6 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) DUF4800 PF16057.5 CDJ88661.1 - 9.4e-05 21.8 0.3 0.00019 20.8 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) IGF2_C PF08365.11 CDJ88661.1 - 0.026 14.5 0.2 0.076 13.0 0.2 1.9 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide Mab-21 PF03281.14 CDJ88662.1 - 6.9e-85 284.9 0.0 8.8e-85 284.6 0.0 1.1 1 0 0 1 1 1 1 Mab-21 protein Frankia_peptide PF14407.6 CDJ88662.1 - 0.044 13.8 0.1 0.51 10.4 0.0 2.2 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Beach PF02138.18 CDJ88663.1 - 1.8e-100 335.9 0.1 2.6e-100 335.4 0.1 1.1 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 CDJ88663.1 - 1.2e-15 57.5 0.1 2.8e-15 56.2 0.1 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 CDJ88663.1 - 1.5e-13 50.9 4.4 0.014 16.3 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ88663.1 - 0.012 15.9 0.1 2.2 8.6 0.0 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 CDJ88663.1 - 0.029 14.4 0.0 0.16 12.0 0.0 2.2 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Thioredoxin PF00085.20 CDJ88665.1 - 1.5e-87 288.3 0.1 2.5e-30 104.5 0.0 3.6 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 CDJ88665.1 - 6.2e-33 114.2 10.8 8.4e-20 71.5 5.3 4.1 2 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CDJ88665.1 - 8.3e-17 61.6 5.4 0.00018 21.9 0.2 5.8 4 2 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CDJ88665.1 - 7.4e-13 48.7 6.1 0.0024 18.2 0.0 6.7 6 3 2 8 8 7 3 Thioredoxin-like OST3_OST6 PF04756.13 CDJ88665.1 - 5.8e-11 42.3 0.9 0.0091 15.4 0.0 4.6 4 1 1 5 5 5 3 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CDJ88665.1 - 5.9e-10 39.2 0.0 0.00012 22.1 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin-like Calsequestrin PF01216.17 CDJ88665.1 - 1.5e-09 37.4 1.7 2.5e-09 36.7 1.3 1.6 1 1 0 1 1 1 1 Calsequestrin AhpC-TSA PF00578.21 CDJ88665.1 - 1.3e-07 31.5 1.7 0.0066 16.4 0.0 3.9 4 1 1 5 5 5 2 AhpC/TSA family Thioredoxin_3 PF13192.6 CDJ88665.1 - 2.9e-07 30.4 0.0 0.11 12.5 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin domain TraF PF13728.6 CDJ88665.1 - 3.8e-07 30.2 0.0 0.65 9.8 0.0 3.5 3 0 0 3 3 3 3 F plasmid transfer operon protein HyaE PF07449.11 CDJ88665.1 - 7.4e-07 29.1 0.1 0.86 9.6 0.0 4.2 4 0 0 4 4 4 2 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.6 CDJ88665.1 - 0.00032 20.9 8.8 0.18 11.9 0.1 5.6 4 2 2 6 6 6 1 Thioredoxin Redoxin PF08534.10 CDJ88665.1 - 0.00033 20.4 2.5 1.1 9.0 0.0 3.6 4 0 0 4 4 4 2 Redoxin DSBA PF01323.20 CDJ88665.1 - 0.0039 17.0 0.7 16 5.2 0.1 4.7 4 2 2 6 6 6 0 DSBA-like thioredoxin domain DUF836 PF05768.14 CDJ88665.1 - 0.0075 16.7 0.0 8.2 6.9 0.0 3.2 3 0 0 3 3 3 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 CDJ88665.1 - 0.018 15.3 9.4 1.8 8.9 0.2 5.4 4 2 0 4 4 4 0 Glutaredoxin OTU PF02338.19 CDJ88666.1 - 2.9e-19 69.8 0.0 6.2e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CDJ88666.1 - 1.6e-05 24.5 2.1 0.016 14.7 0.0 2.5 3 0 0 3 3 3 2 Peptidase C65 Otubain Yippee-Mis18 PF03226.14 CDJ88667.1 - 4.5e-14 52.5 0.6 5.4e-14 52.3 0.6 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HSP20 PF00011.21 CDJ88668.1 - 1.7e-14 53.8 0.0 2.1e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ88668.1 - 4.7e-05 22.9 0.0 6.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA NAD_binding_6 PF08030.12 CDJ88669.1 - 3.9e-22 79.0 0.0 5.5e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CDJ88669.1 - 4.9e-18 65.2 0.0 1.2e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Tho2 PF11262.8 CDJ88670.1 - 4e-77 259.4 1.6 4e-77 259.4 1.6 2.3 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 CDJ88670.1 - 8.3e-63 213.0 9.4 3.7e-38 131.6 0.3 3.5 2 1 1 3 3 3 2 THO complex subunit 2 N-terminus Thoc2 PF11732.8 CDJ88670.1 - 1.9e-29 101.5 0.1 5.3e-29 100.1 0.1 1.8 1 0 0 1 1 1 1 Transcription- and export-related complex subunit PIG-S PF10510.9 CDJ88672.1 - 2.6e-40 138.8 0.3 3.5e-40 138.3 0.3 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Tetraspanin PF00335.20 CDJ88673.1 - 4.6e-58 196.6 8.3 5.9e-58 196.3 8.3 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF308 PF03729.13 CDJ88673.1 - 0.018 15.3 14.1 3.4 8.1 0.6 3.2 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) DUF1129 PF06570.11 CDJ88673.1 - 0.079 12.4 5.0 0.29 10.6 0.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) DUF1218 PF06749.12 CDJ88673.1 - 4.3 7.9 8.6 2.3 8.8 0.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) YiaAB PF05360.14 CDJ88673.1 - 4.6 7.6 11.1 0.71 10.2 0.4 3.2 3 0 0 3 3 3 0 yiaA/B two helix domain DUF872 PF05915.12 CDJ88673.1 - 5.1 7.3 6.6 5.4 7.2 2.9 2.4 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF3040 PF11239.8 CDJ88673.1 - 9.9 6.5 9.4 9.7 6.5 3.7 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) Fer2 PF00111.27 CDJ88674.1 - 1.3e-08 34.6 0.2 1.9e-08 34.2 0.2 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Pkinase PF00069.25 CDJ88676.1 - 2.6e-12 46.7 0.0 3.5e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ88676.1 - 2.2e-06 27.2 0.0 3.3e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 CDJ88676.1 - 0.03 13.3 0.0 0.042 12.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Prenyltransf PF01255.19 CDJ88677.1 - 0.0014 18.2 0.0 0.061 12.8 0.0 2.1 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase V-ATPase_H_N PF03224.14 CDJ88678.1 - 3.5e-96 322.2 8.0 4.2e-96 322.0 8.0 1.1 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 CDJ88678.1 - 6.4e-12 45.6 11.5 2e-11 44.1 2.1 4.3 4 1 0 4 4 4 1 V-ATPase subunit H DUF2326 PF10088.9 CDJ88678.1 - 0.028 14.1 3.2 0.081 12.7 0.1 3.0 3 1 1 4 4 4 0 Uncharacterised protein conserved in bacteria (DUF2326) LuxS PF02664.15 CDJ88678.1 - 0.087 12.5 0.3 0.22 11.2 0.2 1.7 2 0 0 2 2 2 0 S-Ribosylhomocysteinase (LuxS) TMF_TATA_bd PF12325.8 CDJ88678.1 - 0.4 10.9 6.8 9 6.6 4.5 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding IMS PF00817.20 CDJ88679.1 - 1.2e-22 80.5 0.0 1.4e-15 57.6 0.0 2.4 1 1 1 2 2 2 2 impB/mucB/samB family DUF1805 PF08827.11 CDJ88679.1 - 0.00029 21.1 0.0 0.00079 19.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1805) RhoGAP PF00620.27 CDJ88680.1 - 1.9e-39 135.0 0.0 3.9e-39 133.9 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain zf-C2H2_4 PF13894.6 CDJ88681.1 - 4.1e-17 61.4 51.3 0.0014 19.3 0.8 7.4 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2 PF00096.26 CDJ88681.1 - 7.2e-15 54.5 50.8 2.8e-05 24.3 0.6 7.3 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 CDJ88681.1 - 7.9e-14 51.3 34.1 2.6e-05 24.1 1.2 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ88681.1 - 7.2e-08 32.5 29.3 0.016 15.5 0.5 6.8 6 1 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CDJ88681.1 - 3.7e-05 23.9 32.3 0.047 14.0 3.9 4.6 3 1 1 4 4 4 4 Drought induced 19 protein (Di19), zinc-binding Mut7-C PF01927.16 CDJ88681.1 - 0.001 19.2 8.2 0.001 19.2 8.2 2.9 2 1 1 3 3 3 1 Mut7-C RNAse domain zf-met PF12874.7 CDJ88681.1 - 0.0047 17.3 38.2 0.014 15.8 1.7 6.8 7 0 0 7 7 6 3 Zinc-finger of C2H2 type Pox_A_type_inc PF04508.12 CDJ88681.1 - 0.0092 15.8 1.0 0.0092 15.8 1.0 2.4 2 0 0 2 2 1 1 Viral A-type inclusion protein repeat zf-C2HC_2 PF13913.6 CDJ88681.1 - 0.016 15.1 29.2 0.023 14.6 0.1 5.7 6 0 0 6 6 5 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 CDJ88681.1 - 0.021 15.3 49.4 0.18 12.3 0.4 8.2 9 1 0 9 9 8 0 Zinc-finger double domain zf-C2H2_2 PF12756.7 CDJ88681.1 - 0.043 14.1 43.5 1.3 9.4 0.3 7.5 3 2 5 8 8 8 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 CDJ88681.1 - 0.048 13.4 31.3 0.086 12.6 0.0 5.5 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-C2H2_12 PF18658.1 CDJ88681.1 - 0.092 12.3 20.0 1.5 8.5 0.1 5.3 4 1 1 5 5 5 0 Zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 CDJ88681.1 - 0.1 13.3 27.6 0.82 10.4 2.7 4.3 2 1 2 5 5 5 0 Zinc finger C2H2-type, 3 repeats VATC PF18716.1 CDJ88681.1 - 0.56 10.1 8.0 11 5.9 0.0 4.4 4 0 0 4 4 4 0 Vms1-associating treble clef domain Spt46 PF17734.1 CDJ88681.1 - 1.2 8.9 14.1 3 7.6 3.7 3.7 2 2 1 3 3 3 0 Spermatogenesis-associated protein 46 TMPIT PF07851.13 CDJ88681.1 - 3.2 6.9 9.8 5.7 6.1 9.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein zf_C2H2_ZHX PF18387.1 CDJ88681.1 - 5.9 6.6 18.0 15 5.3 2.7 4.6 3 2 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain Ge1_WD40 PF16529.5 CDJ88682.1 - 5.5e-49 166.9 0.0 7.5e-49 166.5 0.0 1.2 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Pkinase PF00069.25 CDJ88683.1 - 7.4e-49 166.5 0.0 2.6e-48 164.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ88683.1 - 1.9e-27 96.2 0.0 2.5e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ88683.1 - 8.7e-05 22.0 0.0 0.00016 21.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CDJ88683.1 - 0.00017 20.7 0.0 0.00019 20.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CDJ88683.1 - 0.00033 19.6 0.0 0.00045 19.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDJ88683.1 - 0.00033 20.1 0.3 0.00094 18.6 0.3 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ88683.1 - 0.00072 19.5 0.1 0.013 15.5 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 CDJ88683.1 - 0.013 15.2 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 CDJ88683.1 - 0.085 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PIP49_C PF12260.8 CDJ88683.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Astacin PF01400.24 CDJ88684.1 - 1.7e-27 96.3 0.4 2e-27 96.1 0.4 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 CDJ88684.1 - 0.017 15.0 0.0 4.6 7.1 0.0 2.1 2 0 0 2 2 2 0 Matrixin DUF2268 PF10026.9 CDJ88684.1 - 0.071 12.7 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) BTB PF00651.31 CDJ88685.1 - 8.2e-18 64.7 0.2 6.8e-16 58.5 0.0 2.5 1 1 1 2 2 2 2 BTB/POZ domain tRNA-synt_1 PF00133.22 CDJ88686.1 - 8.5e-39 133.3 0.2 7e-15 54.3 0.4 4.3 2 2 1 4 4 4 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CDJ88686.1 - 2.7e-25 88.9 0.0 5.1e-18 65.0 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CDJ88686.1 - 4.5e-06 26.2 0.0 0.053 12.9 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 CDJ88686.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA DUF2070 PF09843.9 CDJ88688.1 - 0.014 13.8 4.8 0.018 13.4 4.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DDDD PF10161.9 CDJ88688.1 - 0.093 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Putative mitochondrial precursor protein GTP_EFTU PF00009.27 CDJ88689.1 - 0.00072 19.1 0.0 0.00096 18.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBD PF18534.1 CDJ88689.1 - 0.12 12.5 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 Helical bundle domain MMR_HSR1 PF01926.23 CDJ88689.1 - 0.14 12.3 0.1 1.5 9.0 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase MADF_DNA_bdg PF10545.9 CDJ88690.1 - 1.1e-10 41.6 3.3 1.1e-10 41.6 3.3 3.0 4 0 0 4 4 4 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_3 PF12776.7 CDJ88690.1 - 0.0014 19.5 0.3 0.0014 19.5 0.3 2.8 2 1 1 3 3 3 1 Myb/SANT-like DNA-binding domain Swi6_N PF18530.1 CDJ88690.1 - 0.011 15.9 0.5 0.038 14.1 0.5 1.9 1 0 0 1 1 1 0 Swi6 N-terminal domain Myb_DNA-bind_5 PF13873.6 CDJ88690.1 - 0.031 14.3 5.4 0.06 13.4 3.3 2.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF5388 PF17363.2 CDJ88690.1 - 0.07 13.3 0.0 28 5.0 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5388) Dict-STAT-coil PF09267.10 CDJ88690.1 - 0.12 12.7 0.9 0.31 11.4 0.1 2.1 2 0 0 2 2 2 0 Dictyostelium STAT, coiled coil Snapin_Pallidin PF14712.6 CDJ88690.1 - 0.27 11.7 5.2 3.3 8.2 0.3 3.0 2 0 0 2 2 2 0 Snapin/Pallidin FUSC PF04632.12 CDJ88690.1 - 0.38 9.2 1.0 0.61 8.5 1.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family ADIP PF11559.8 CDJ88690.1 - 2.4 8.2 14.8 0.16 12.0 5.0 3.1 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding PQ-loop PF04193.14 CDJ88691.1 - 5.4e-18 64.5 0.1 1e-17 63.6 0.1 1.5 1 0 0 1 1 1 1 PQ loop repeat Pkinase PF00069.25 CDJ88692.1 - 3.2e-73 246.4 0.0 3.6e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ88692.1 - 8.1e-31 107.2 0.0 1.5e-30 106.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ88692.1 - 1.2e-05 24.5 0.0 3.7e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CDJ88692.1 - 0.00012 21.5 0.1 0.13 11.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CDJ88692.1 - 0.04 13.8 0.2 0.061 13.2 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family 7TM_GPCR_Srt PF10321.9 CDJ88693.1 - 1.5e-10 40.5 6.5 1.8e-10 40.3 6.5 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt DUF3021 PF11457.8 CDJ88693.1 - 3 8.2 12.4 11 6.3 12.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) Peptidase_C1 PF00112.23 CDJ88694.1 - 2.6e-37 129.1 14.3 2.6e-37 129.1 7.5 2.0 2 0 0 2 2 2 2 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ88694.1 - 0.00012 21.0 0.8 0.00018 20.4 0.8 1.2 1 0 0 1 1 1 1 Peptidase C1-like family RVT_1 PF00078.27 CDJ88695.1 - 5.6e-36 124.1 0.0 6.8e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C1 PF00112.23 CDJ88696.1 - 5.5e-41 141.0 5.7 6.7e-41 140.8 5.7 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ88696.1 - 0.00018 20.4 0.7 0.00025 19.9 0.7 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ88697.1 - 2.2e-64 217.6 9.7 2.7e-64 217.3 9.7 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ88697.1 - 9.9e-05 21.3 1.7 0.002 16.9 0.4 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ88698.1 - 3.2e-61 207.2 13.3 4.1e-61 206.8 13.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ88698.1 - 0.00024 20.0 1.6 0.00024 20.0 1.6 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ88699.1 - 5.6e-63 212.9 9.5 7.2e-63 212.6 9.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ88699.1 - 0.0021 16.9 4.6 0.022 13.5 1.2 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Exo_endo_phos PF03372.23 CDJ88700.1 - 0.0064 16.0 0.2 0.01 15.3 0.2 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-C3HC4_4 PF15227.6 CDJ88702.1 - 2.7e-08 33.8 3.0 2.7e-08 33.8 3.0 3.0 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 CDJ88702.1 - 2e-07 30.8 1.9 2e-07 30.8 1.9 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ88702.1 - 4.8e-07 29.7 3.1 4.8e-07 29.7 3.1 2.8 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDJ88702.1 - 1.7e-06 27.8 3.7 1.7e-06 27.8 3.7 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ88702.1 - 4.1e-06 26.7 2.8 4.1e-06 26.7 2.8 3.4 4 0 0 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.6 CDJ88702.1 - 2.5e-05 24.5 4.4 2.5e-05 24.5 4.4 3.0 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDJ88702.1 - 0.00022 21.0 3.1 0.00022 21.0 3.1 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 CDJ88702.1 - 0.013 15.3 1.9 0.017 15.0 0.2 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Fzo_mitofusin PF04799.13 CDJ88703.1 - 0.03 13.9 0.1 0.053 13.1 0.1 1.3 1 0 0 1 1 1 0 fzo-like conserved region TMEM70 PF06979.12 CDJ88704.1 - 8.8e-18 65.0 4.8 1.4e-17 64.4 4.6 1.4 1 1 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex TEBP_beta PF07404.11 CDJ88704.1 - 0.15 11.4 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) Ntox30 PF15532.6 CDJ88705.1 - 0.035 14.5 0.0 0.073 13.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial toxin 30 hEGF PF12661.7 CDJ88706.1 - 0.012 16.3 9.8 0.056 14.1 1.4 3.3 2 0 0 2 2 2 0 Human growth factor-like EGF EGF PF00008.27 CDJ88706.1 - 0.069 13.5 7.4 0.069 13.5 1.2 3.1 2 0 0 2 2 2 0 EGF-like domain EGF_3 PF12947.7 CDJ88706.1 - 5.6 7.2 7.2 1.2 9.4 1.2 2.9 2 0 0 2 2 2 0 EGF domain ShK PF01549.24 CDJ88707.1 - 4.1e-06 27.2 20.9 0.0002 21.9 5.3 2.9 2 1 0 2 2 2 2 ShK domain-like ShK PF01549.24 CDJ88708.1 - 1.1e-05 25.8 23.1 0.0017 18.9 7.5 3.5 2 1 0 2 2 2 2 ShK domain-like ABC2_membrane_3 PF12698.7 CDJ88709.1 - 1.6e-18 66.9 11.1 2.9e-18 66.1 11.1 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 CDJ88709.1 - 1.6e-08 34.2 16.0 9.5e-05 21.9 11.5 2.3 2 0 0 2 2 2 2 ABC-2 type transporter Yip1 PF04893.17 CDJ88709.1 - 0.13 12.0 10.0 0.15 11.7 8.2 1.9 2 0 0 2 2 2 0 Yip1 domain WD40 PF00400.32 CDJ88710.1 - 1.4e-40 136.5 30.4 4e-07 30.6 0.7 12.6 12 1 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ88710.1 - 9.6e-25 86.7 7.8 0.00027 21.2 0.0 9.8 4 2 5 9 9 9 8 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 CDJ88710.1 - 1.4e-06 27.5 6.9 0.01 14.8 0.1 4.1 3 1 0 3 3 3 3 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 CDJ88710.1 - 9.4e-06 25.2 9.1 0.24 10.7 0.4 5.0 3 2 0 4 4 4 3 WD40-like domain Mcl1_mid PF12341.8 CDJ88710.1 - 0.00033 20.1 4.6 0.097 12.0 0.0 3.2 3 0 0 3 3 3 1 Minichromosome loss protein, Mcl1, middle region Ge1_WD40 PF16529.5 CDJ88710.1 - 0.0055 15.7 10.0 0.43 9.5 0.3 4.8 4 1 0 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein R3H-assoc PF13902.6 CDJ88710.1 - 0.17 12.3 0.5 1.1 9.6 0.0 2.4 3 0 0 3 3 3 0 R3H-associated N-terminal domain EGF_2 PF07974.13 CDJ88711.1 - 5.1 7.6 31.1 3.1 8.2 1.0 4.5 4 0 0 4 4 4 0 EGF-like domain Carla_C4 PF01623.17 CDJ88711.1 - 8.9 6.3 9.5 7.1 6.7 1.2 2.6 1 1 1 2 2 2 0 Carlavirus putative nucleic acid binding protein LIM PF00412.22 CDJ88712.1 - 9.1e-11 41.8 0.3 9.9e-11 41.7 0.3 1.1 1 0 0 1 1 1 1 LIM domain DUF2685 PF10886.8 CDJ88712.1 - 0.0072 16.5 0.1 0.01 16.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2685) Fer4_4 PF12800.7 CDJ88712.1 - 0.8 10.4 5.6 15 6.4 1.4 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain DUF273 PF03314.14 CDJ88713.1 - 4.2e-57 193.2 2.4 6.2e-57 192.7 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Glyco_transf_34 PF05637.12 CDJ88713.1 - 0.0085 15.8 0.5 0.049 13.4 0.1 1.9 1 1 1 2 2 2 1 galactosyl transferase GMA12/MNN10 family Glyco_tranf_2_4 PF13704.6 CDJ88713.1 - 0.03 14.8 0.0 0.09 13.3 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 2 MFS_1 PF07690.16 CDJ88714.1 - 6.9e-28 97.6 37.7 6.9e-28 97.6 37.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Collagen PF01391.18 CDJ88715.1 - 5.4e-22 77.3 106.4 3.6e-05 23.4 6.9 4.1 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ88715.1 - 1.4e-17 63.5 0.9 1.7e-17 63.2 0.9 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ88716.1 - 4.5e-22 77.6 107.7 1.3e-05 24.9 44.4 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ88716.1 - 1.6e-17 63.3 0.8 2e-17 63.0 0.8 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain RVT_1 PF00078.27 CDJ88717.1 - 3.2e-09 36.6 0.0 6.8e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mur_ligase_C PF02875.21 CDJ88718.1 - 3.1e-05 24.2 0.0 5.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.12 CDJ88718.1 - 0.02 14.9 0.0 0.052 13.5 0.0 1.7 1 1 0 1 1 1 0 Mur ligase middle domain SNF PF00209.18 CDJ88719.1 - 1.7e-20 73.2 36.2 2e-13 49.9 6.4 2.1 2 0 0 2 2 2 2 Sodium:neurotransmitter symporter family HemY_N PF07219.13 CDJ88719.1 - 4.8 7.4 9.0 13 6.0 0.1 4.4 4 0 0 4 4 4 0 HemY protein N-terminus Pkinase PF00069.25 CDJ88720.1 - 3.2e-134 446.3 0.0 6.9e-67 225.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ88720.1 - 4.1e-65 219.6 0.0 5.8e-32 111.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CDJ88720.1 - 1.5e-13 51.2 3.0 7.5e-05 22.8 0.0 4.2 2 2 2 4 4 4 3 Phosphotransferase enzyme family Kinase-like PF14531.6 CDJ88720.1 - 2.8e-11 43.3 0.0 0.00018 20.9 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CDJ88720.1 - 5.3e-11 42.3 1.6 9.3e-06 25.1 0.1 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.24 CDJ88720.1 - 1.4e-07 32.1 0.2 4.3e-07 30.5 0.2 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CDJ88720.1 - 5.9e-06 25.5 0.8 0.0036 16.3 0.1 2.3 2 0 0 2 2 2 2 Haspin like kinase domain RIO1 PF01163.22 CDJ88720.1 - 1.5e-05 24.7 0.5 0.00063 19.4 0.0 2.5 2 0 0 2 2 2 1 RIO1 family YrbL-PhoP_reg PF10707.9 CDJ88720.1 - 8.5e-05 22.2 0.2 0.031 13.8 0.1 2.3 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 CDJ88720.1 - 0.00011 21.1 0.0 0.57 8.9 0.0 2.7 3 0 0 3 3 3 2 Fungal protein kinase FTA2 PF13095.6 CDJ88720.1 - 0.0012 18.5 0.5 3.9 7.0 0.0 3.3 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 CDJ88720.1 - 0.009 15.6 0.0 0.17 11.4 0.0 2.3 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF1679 PF07914.11 CDJ88720.1 - 0.089 11.6 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Rotamase PF00639.21 CDJ88720.1 - 0.12 13.3 0.2 1.8 9.6 0.0 2.6 2 0 0 2 2 2 0 PPIC-type PPIASE domain Maf PF02545.14 CDJ88721.1 - 1.8e-23 83.2 0.0 1.9e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein DUF2048 PF09752.9 CDJ88722.1 - 8.3e-105 350.7 0.0 9.4e-105 350.6 0.0 1.0 1 0 0 1 1 1 1 Abhydrolase domain containing 18 Abhydrolase_6 PF12697.7 CDJ88722.1 - 4.1e-06 27.6 1.1 5.6e-06 27.1 1.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 CDJ88722.1 - 0.059 13.0 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Plug PF07715.15 CDJ88722.1 - 0.13 12.8 0.0 1.9 9.1 0.0 2.6 2 1 0 2 2 2 0 TonB-dependent Receptor Plug Domain Hydrolase_4 PF12146.8 CDJ88722.1 - 0.15 11.3 0.1 0.45 9.7 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 LRR_8 PF13855.6 CDJ88723.1 - 8.4e-58 192.0 56.3 4.3e-13 48.8 6.1 7.6 2 2 5 7 7 7 7 Leucine rich repeat eIF-5_eIF-2B PF01873.17 CDJ88723.1 - 2.1e-39 134.0 0.9 2.1e-39 134.0 0.9 1.9 2 0 0 2 2 2 1 Domain found in IF2B/IF5 LRR_4 PF12799.7 CDJ88723.1 - 3.1e-28 97.3 59.9 4e-05 23.9 5.2 9.2 5 3 3 9 9 9 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CDJ88723.1 - 1.3e-19 70.4 7.9 7.4e-08 32.4 0.5 4.3 2 2 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 CDJ88723.1 - 3.1e-13 49.6 29.0 2.3e-05 24.0 5.1 4.9 2 1 4 6 6 6 3 Leucine-rich repeat LRR_1 PF00560.33 CDJ88723.1 - 0.0097 16.3 44.4 23 6.0 0.5 13.4 14 0 0 14 14 14 1 Leucine Rich Repeat DUF3144 PF11342.8 CDJ88724.1 - 0.04 14.2 1.1 7.7 6.9 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3144) Cytochrom_C1 PF02167.15 CDJ88725.1 - 5.8e-88 294.3 0.0 6.9e-88 294.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrom_C PF00034.21 CDJ88725.1 - 0.00046 21.3 0.8 0.0033 18.5 0.3 2.2 2 1 0 2 2 2 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CDJ88725.1 - 0.0012 19.1 0.1 0.0032 17.7 0.1 1.8 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III MMS1_N PF10433.9 CDJ88726.1 - 3.3e-163 543.8 0.0 7.5e-163 542.7 0.0 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CDJ88726.1 - 6.5e-90 301.7 0.0 6.4e-89 298.4 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region 7tm_1 PF00001.21 CDJ88727.1 - 2.9e-11 43.2 0.0 3.1e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) AdoHcyase PF05221.17 CDJ88728.1 - 2.3e-137 457.1 0.0 1.8e-74 250.6 0.1 2.2 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase Adap_comp_sub PF00928.21 CDJ88728.1 - 8.2e-89 297.5 0.0 3.5e-88 295.4 0.0 1.9 2 0 0 2 2 2 1 Adaptor complexes medium subunit family AdoHcyase_NAD PF00670.21 CDJ88728.1 - 2.6e-82 274.7 0.7 5.2e-82 273.7 0.7 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 CDJ88728.1 - 4.1e-07 29.5 0.0 9.2e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CDJ88728.1 - 8.7e-06 25.4 0.1 1.7e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Clat_adaptor_s PF01217.20 CDJ88728.1 - 1.4e-05 25.1 1.7 2.4e-05 24.3 1.7 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TrkA_N PF02254.18 CDJ88728.1 - 0.00053 20.2 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain MIF PF01187.18 CDJ88729.1 - 2.4e-36 124.5 0.0 2.7e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 CDJ88729.1 - 0.012 15.5 0.0 0.074 13.0 0.0 2.0 2 0 0 2 2 2 0 Tautomerase enzyme COMPASS-Shg1 PF05205.12 CDJ88730.1 - 1.2e-07 32.4 0.9 1.8e-07 31.8 0.9 1.3 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 DUF1816 PF08846.10 CDJ88730.1 - 0.15 12.1 0.0 8.3 6.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1816) zf-C2H2 PF00096.26 CDJ88731.1 - 5.8e-13 48.5 27.8 0.00017 21.9 3.5 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ88731.1 - 5.1e-10 39.3 8.5 5.2e-07 29.8 1.3 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDJ88731.1 - 1.2e-06 28.8 25.8 0.0063 17.3 3.4 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 CDJ88731.1 - 0.0027 18.3 7.7 0.029 15.0 1.3 3.0 1 1 1 2 2 2 1 FOXP coiled-coil domain IBR PF01485.21 CDJ88731.1 - 0.058 13.6 4.1 2.5 8.4 4.1 2.5 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain DUF212 PF02681.14 CDJ88731.1 - 0.081 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Divergent PAP2 family HTH_18 PF12833.7 CDJ88731.1 - 0.097 13.0 1.6 57 4.1 0.0 3.8 3 0 0 3 3 3 0 Helix-turn-helix domain zf-C2H2_jaz PF12171.8 CDJ88731.1 - 0.11 12.9 2.9 6.6 7.2 0.3 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding HMGL-like PF00682.19 CDJ88731.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 HMGL-like zf-C2HE PF16278.5 CDJ88731.1 - 0.97 9.9 5.6 1.2 9.7 0.6 2.8 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 CDJ88731.1 - 1.6 8.5 15.5 1.1 9.1 0.1 4.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Pkinase PF00069.25 CDJ88732.1 - 0.00079 18.9 0.0 0.00089 18.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Neur_chan_LBD PF02931.23 CDJ88733.1 - 4.7e-58 196.2 0.1 6.6e-58 195.7 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ88733.1 - 1.3e-54 185.8 0.5 1.7e-54 185.4 0.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Collagen PF01391.18 CDJ88734.1 - 7e-22 77.0 62.1 1.7e-10 40.5 28.9 3.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ88734.1 - 0.22 11.6 0.3 0.37 10.9 0.3 1.3 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Tubulin PF00091.25 CDJ88735.1 - 9.9e-69 231.5 0.0 1.4e-68 231.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDJ88735.1 - 3.2e-50 169.5 0.0 5.1e-50 168.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CDJ88735.1 - 0.00095 18.9 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain MSP PF01716.18 CDJ88735.1 - 0.18 11.0 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide RVT_1 PF00078.27 CDJ88736.1 - 0.00057 19.5 0.0 0.00077 19.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DHHC PF01529.20 CDJ88737.1 - 0.073 13.2 10.1 1.4 9.1 10.1 2.5 1 1 0 1 1 1 0 DHHC palmitoyltransferase Peptidase_U4 PF03419.13 CDJ88737.1 - 2 7.6 12.0 0.16 11.2 5.5 2.0 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Cation_ATPase_C PF00689.21 CDJ88738.1 - 2.9e-40 137.9 7.5 2.9e-40 137.9 7.5 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CDJ88738.1 - 1.8e-29 102.6 11.1 2.5e-22 79.3 0.1 3.2 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase PF13246.6 CDJ88738.1 - 1.3e-19 70.1 0.0 2.9e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CDJ88738.1 - 7.9e-13 49.2 0.2 1.2e-11 45.3 0.2 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CDJ88738.1 - 1.3e-12 47.2 0.0 2.7e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CDJ88738.1 - 5.7e-05 23.0 0.2 5.7e-05 23.0 0.2 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase RRM_DME PF15628.6 CDJ88738.1 - 0.11 12.7 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 RRM in Demeter Elongin_A PF06881.11 CDJ88738.1 - 0.12 12.9 3.4 0.29 11.7 3.4 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Pinin_SDK_memA PF04696.13 CDJ88738.1 - 0.56 10.3 11.5 1 9.4 11.5 1.3 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Homeodomain PF00046.29 CDJ88739.1 - 0.0058 16.4 4.3 0.0058 16.4 4.3 1.7 2 0 0 2 2 2 1 Homeodomain RVT_1 PF00078.27 CDJ88742.1 - 2.1e-23 83.0 0.0 2.7e-23 82.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CDJ88743.1 - 6.1e-25 88.0 0.0 9.4e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 CDJ88744.1 - 9.8e-08 32.6 2.1 0.0087 16.9 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ88744.1 - 0.00029 21.1 0.1 0.13 12.6 0.0 3.6 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CDJ88744.1 - 0.2 12.2 0.2 2.8 8.6 0.0 2.9 5 0 0 5 5 5 0 PQQ-like domain DUF848 PF05852.11 CDJ88745.1 - 0.0028 17.8 0.9 0.0028 17.8 0.9 5.0 3 1 1 4 4 4 1 Gammaherpesvirus protein of unknown function (DUF848) BST2 PF16716.5 CDJ88745.1 - 0.0053 17.3 1.1 0.0053 17.3 1.1 8.3 5 2 4 9 9 9 1 Bone marrow stromal antigen 2 TPR_MLP1_2 PF07926.12 CDJ88745.1 - 0.0063 16.6 2.3 0.0063 16.6 2.3 6.0 4 1 1 5 5 5 2 TPR/MLP1/MLP2-like protein Mon1 PF03164.14 CDJ88746.1 - 2e-81 274.2 0.2 2.4e-81 273.9 0.2 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Mpp10 PF04006.12 CDJ88747.1 - 1.4e-105 354.1 55.8 2.5e-105 353.2 55.8 1.4 1 1 0 1 1 1 1 Mpp10 protein PilJ PF13675.6 CDJ88747.1 - 0.023 14.7 1.5 0.085 12.9 0.5 2.3 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Aminopep PF10023.9 CDJ88748.1 - 1.8 7.8 11.4 3.1 7.1 11.4 1.3 1 0 0 1 1 1 0 Putative aminopeptidase Ribosomal_L22 PF00237.19 CDJ88749.1 - 4.5e-17 62.2 0.1 1.1e-16 60.9 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e RVT_1 PF00078.27 CDJ88750.1 - 1.6e-14 54.0 0.0 1.6e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CAP PF00188.26 CDJ88751.1 - 2.1e-17 64.1 0.4 3.1e-17 63.6 0.4 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family C2 PF00168.30 CDJ88752.1 - 6.3e-54 180.6 0.4 1.4e-27 96.0 0.0 2.4 3 0 0 3 3 3 2 C2 domain CEP76-C2 PF15627.6 CDJ88752.1 - 0.00011 21.8 0.0 0.23 11.0 0.0 2.3 2 0 0 2 2 2 2 CEP76 C2 domain Transglut_C PF00927.22 CDJ88752.1 - 0.00052 20.1 0.4 0.22 11.7 0.0 2.4 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain DOCK-C2 PF14429.6 CDJ88752.1 - 0.009 15.8 0.0 0.47 10.2 0.0 2.2 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF5049 PF16468.5 CDJ88754.1 - 0.065 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5049) SpoIIIAH PF12685.7 CDJ88755.1 - 0.006 16.4 11.5 0.017 15.0 11.5 1.7 1 1 0 1 1 1 1 SpoIIIAH-like protein Mem_trans PF03547.18 CDJ88755.1 - 0.0065 14.9 3.9 0.0073 14.7 3.9 1.1 1 0 0 1 1 1 1 Membrane transport protein DUF4834 PF16118.5 CDJ88755.1 - 0.01 16.8 0.7 0.01 16.8 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) V_ATPase_I PF01496.19 CDJ88755.1 - 0.016 13.2 8.7 0.017 13.1 8.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Inhibitor_I53 PF11714.8 CDJ88755.1 - 0.017 15.3 0.0 0.017 15.3 0.0 2.3 1 1 1 2 2 2 0 Thrombin inhibitor Madanin Draxin PF15550.6 CDJ88755.1 - 0.035 14.0 14.0 0.044 13.6 14.0 1.0 1 0 0 1 1 1 0 Draxin FAM209 PF15206.6 CDJ88755.1 - 0.053 13.3 0.1 0.053 13.3 0.1 2.0 1 1 1 2 2 2 0 FAM209 family Conotoxin PF02950.17 CDJ88755.1 - 0.078 14.0 10.2 9.9 7.3 10.2 2.7 1 1 0 1 1 1 0 Conotoxin FAM76 PF16046.5 CDJ88755.1 - 0.083 12.2 21.2 0.1 11.9 21.2 1.1 1 0 0 1 1 1 0 FAM76 protein Presenilin PF01080.17 CDJ88755.1 - 0.11 11.3 13.3 0.14 10.9 13.3 1.2 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 CDJ88755.1 - 0.12 12.4 14.6 0.14 12.2 14.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A SLC12 PF03522.15 CDJ88755.1 - 0.17 10.9 12.5 0.19 10.7 12.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 O-antigen_lig PF13425.6 CDJ88755.1 - 0.34 9.7 0.2 0.36 9.5 0.2 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SID-1_RNA_chan PF13965.6 CDJ88755.1 - 0.43 8.9 3.0 0.6 8.5 3.0 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ASD2 PF08687.11 CDJ88755.1 - 0.59 9.6 13.7 0.74 9.3 13.7 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Neur_chan_memb PF02932.16 CDJ88755.1 - 0.63 10.1 8.6 0.81 9.7 8.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Apt1 PF10351.9 CDJ88755.1 - 0.68 8.7 23.5 0.81 8.5 23.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain PI3K_1B_p101 PF10486.9 CDJ88755.1 - 0.72 7.6 15.3 0.81 7.4 15.3 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Menin PF05053.13 CDJ88755.1 - 0.77 8.0 9.1 0.9 7.8 9.1 1.0 1 0 0 1 1 1 0 Menin OATP PF03137.20 CDJ88755.1 - 0.95 7.7 9.0 2.2 6.4 8.9 1.7 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family NicO PF03824.16 CDJ88755.1 - 1.1 8.5 11.0 1.3 8.3 11.0 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein Peptidase_S49_N PF08496.10 CDJ88755.1 - 1.6 8.7 9.7 2.1 8.4 9.4 1.5 1 1 0 1 1 1 0 Peptidase family S49 N-terminal MMM1 PF10296.9 CDJ88755.1 - 1.8 7.5 10.2 7.8 5.4 10.2 1.8 1 1 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Macoilin PF09726.9 CDJ88755.1 - 1.8 7.0 27.0 2.1 6.8 27.0 1.0 1 0 0 1 1 1 0 Macoilin family ALMT PF11744.8 CDJ88755.1 - 1.9 7.2 12.5 2.1 7.1 12.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter FAM176 PF14851.6 CDJ88755.1 - 1.9 8.1 15.9 0.63 9.7 8.7 2.1 1 1 1 2 2 2 0 FAM176 family MCM_bind PF09739.9 CDJ88755.1 - 2 6.8 13.0 2.3 6.6 13.0 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor EphA2_TM PF14575.6 CDJ88755.1 - 6.1 7.8 9.3 90 4.1 9.3 2.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CRA PF06589.11 CDJ88755.1 - 8.1 6.6 13.6 35 4.5 13.6 1.9 1 1 0 1 1 1 0 Circumsporozoite-related antigen (CRA) PNISR PF15996.5 CDJ88755.1 - 8.8 6.5 18.8 11 6.2 18.8 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR NST1 PF13945.6 CDJ88755.1 - 9 6.4 20.9 11 6.0 20.9 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Apis_Csd PF11671.8 CDJ88755.1 - 9.4 6.2 7.1 13 5.8 7.1 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein FERM_M PF00373.18 CDJ88756.1 - 6.7e-41 139.4 0.5 1.2e-40 138.6 0.5 1.4 1 0 0 1 1 1 1 FERM central domain Kindlin_2_N PF18124.1 CDJ88756.1 - 1.3e-35 121.4 0.5 3.1e-35 120.2 0.5 1.7 1 0 0 1 1 1 1 Kindlin-2 N-terminal domain PH PF00169.29 CDJ88756.1 - 1.1e-08 35.5 0.0 2.4e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 PH domain FERM_N PF09379.10 CDJ88756.1 - 0.012 15.5 0.2 0.24 11.3 0.0 2.7 2 1 0 2 2 2 0 FERM N-terminal domain PH_11 PF15413.6 CDJ88756.1 - 0.041 14.3 0.4 0.25 11.8 0.0 2.6 2 2 0 2 2 2 0 Pleckstrin homology domain PH_8 PF15409.6 CDJ88756.1 - 0.062 13.6 0.0 0.21 11.9 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain Histone PF00125.24 CDJ88757.1 - 3e-15 56.8 0.2 5.7e-15 55.8 0.2 1.6 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 HOIP-UBA PF16678.5 CDJ88757.1 - 0.1 12.6 0.4 3.5 7.6 0.0 2.1 2 0 0 2 2 2 0 HOIP UBA domain pair NTP_transf_2 PF01909.23 CDJ88758.1 - 0.0074 16.6 0.0 0.021 15.1 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Ly-6_related PF06579.12 CDJ88759.1 - 0.18 12.0 5.2 2.1 8.6 5.2 2.1 1 1 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein NmrA PF05368.13 CDJ88759.1 - 0.21 11.1 0.0 0.29 10.7 0.0 1.1 1 0 0 1 1 1 0 NmrA-like family QVR PF17064.5 CDJ88759.1 - 6.1 7.2 9.5 79 3.6 9.5 2.5 1 1 0 1 1 1 0 Sleepless protein C2 PF00168.30 CDJ88760.1 - 1.2e-05 25.6 0.0 1.5e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 C2 domain PIEZO PF15917.5 CDJ88761.1 - 2.1e-45 155.0 3.0 2.5e-38 131.8 2.4 2.2 1 1 1 2 2 2 2 Piezo Amidase PF01425.21 CDJ88761.1 - 0.016 14.2 0.1 0.025 13.6 0.1 1.1 1 0 0 1 1 1 0 Amidase HTH_48 PF17906.1 CDJ88762.1 - 4.4e-09 36.3 0.3 6.4e-09 35.8 0.3 1.2 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 CDJ88762.1 - 0.0016 19.0 0.1 0.0024 18.4 0.1 1.4 1 1 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 CDJ88762.1 - 0.0055 16.5 0.2 0.04 13.7 0.1 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 CDJ88762.1 - 0.0097 16.0 0.2 0.099 12.8 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 CDJ88762.1 - 0.012 16.1 2.0 2.2 8.8 0.1 2.1 1 1 1 2 2 2 0 leucine-zipper of insertion element IS481 HTH_29 PF13551.6 CDJ88762.1 - 0.015 15.3 0.1 0.21 11.7 0.1 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_IS630 PF01710.16 CDJ88762.1 - 0.049 13.7 0.0 0.056 13.5 0.0 1.0 1 0 0 1 1 1 0 Transposase HTH_50 PF18024.1 CDJ88762.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain SEP PF08059.13 CDJ88763.1 - 2.7e-23 82.3 0.0 5.1e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 CDJ88763.1 - 6e-16 58.4 0.0 9.6e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 UBX domain Vpu PF00558.19 CDJ88763.1 - 0.74 9.6 4.4 4.5 7.1 0.3 2.2 2 0 0 2 2 2 0 Vpu protein NDUFA12 PF05071.16 CDJ88764.1 - 2.1e-30 105.4 7.3 2.6e-30 105.1 7.3 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Lectin_C PF00059.21 CDJ88765.1 - 1.7e-37 128.5 1.1 2.4e-18 66.8 0.6 2.1 2 0 0 2 2 2 2 Lectin C-type domain Lectin_C PF00059.21 CDJ88766.1 - 2.8e-38 130.9 2.9 5.9e-20 72.0 1.8 2.1 2 0 0 2 2 2 2 Lectin C-type domain DUF4846 PF16138.5 CDJ88766.1 - 0.14 11.6 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (4846) UL45 PF05473.12 CDJ88766.1 - 0.16 11.6 2.8 0.84 9.2 0.1 2.5 2 1 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like CPG4 PF15481.6 CDJ88767.1 - 8.8e-36 122.4 30.8 4.1e-19 69.0 8.2 3.1 4 0 0 4 4 4 2 Chondroitin proteoglycan 4 UPAR_LY6_2 PF16975.5 CDJ88767.1 - 0.66 10.2 10.0 0.074 13.3 1.3 2.6 2 0 0 2 2 2 0 Ly6/PLAUR domain-containing protein 6, Lypd6 Collagen PF01391.18 CDJ88768.1 - 1.2e-24 85.8 103.2 5.5e-10 38.8 38.1 3.4 3 0 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ88768.1 - 7.3e-19 67.6 0.1 9.3e-19 67.2 0.1 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain COX14 PF14880.6 CDJ88768.1 - 0.043 13.7 2.2 0.074 12.9 2.2 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c assembly ShK PF01549.24 CDJ88769.1 - 4.2e-05 24.0 4.4 0.00011 22.7 4.4 1.9 1 1 0 1 1 1 1 ShK domain-like ShK PF01549.24 CDJ88770.1 - 4.3e-05 24.0 1.1 4.3e-05 24.0 1.1 1.9 2 1 0 2 2 2 1 ShK domain-like Collagen PF01391.18 CDJ88771.1 - 6.8e-24 83.4 86.1 2.5e-05 23.9 6.6 4.2 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ88771.1 - 1.2e-19 70.1 0.3 1.8e-19 69.5 0.3 1.3 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain COX14 PF14880.6 CDJ88771.1 - 0.52 10.2 2.2 0.77 9.6 2.2 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c assembly DDE_Tnp_1_7 PF13843.6 CDJ88772.1 - 1.4e-48 166.0 0.1 1.7e-48 165.7 0.1 1.1 1 0 0 1 1 1 1 Transposase IS4 Kelch_1 PF01344.25 CDJ88773.1 - 1.8e-62 206.7 22.0 5.5e-11 41.9 0.0 6.7 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 CDJ88773.1 - 4.7e-46 153.7 1.1 8.3e-08 32.3 0.0 6.3 1 1 5 6 6 6 6 Kelch motif BACK PF07707.15 CDJ88773.1 - 5.6e-31 106.7 2.9 3.9e-30 104.0 0.8 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 CDJ88773.1 - 1.6e-28 99.1 0.1 3e-28 98.3 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 CDJ88773.1 - 3.4e-27 93.4 4.0 0.0015 18.4 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 CDJ88773.1 - 5.7e-24 83.9 9.0 0.0037 17.5 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.6 CDJ88773.1 - 1.4e-16 60.2 6.8 0.0086 16.1 0.0 6.6 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ88773.1 - 3.5e-12 46.0 7.3 0.12 12.4 0.2 6.7 7 0 0 7 7 7 4 Kelch motif PQQ_3 PF13570.6 CDJ88773.1 - 0.069 13.7 7.0 38 4.9 0.2 5.0 5 0 0 5 5 5 0 PQQ-like domain Kelch_1 PF01344.25 CDJ88774.1 - 2e-10 40.1 0.3 0.0039 16.8 0.0 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 CDJ88774.1 - 0.0069 16.6 0.9 23 5.5 0.0 3.4 2 1 1 3 3 3 1 Kelch motif Kelch_4 PF13418.6 CDJ88774.1 - 0.0071 16.3 0.7 5.8 7.0 0.0 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ88774.1 - 0.05 13.9 0.1 5.9 7.3 0.1 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain ATP-grasp PF02222.22 CDJ88774.1 - 0.058 13.0 0.0 0.076 12.6 0.0 1.1 1 0 0 1 1 1 0 ATP-grasp domain HLH PF00010.26 CDJ88776.1 - 4.2e-22 77.8 1.9 2.4e-15 56.2 1.5 2.8 2 0 0 2 2 2 2 Helix-loop-helix DNA-binding domain CLAMP PF14769.6 CDJ88776.1 - 0.007 16.8 0.0 7.9 7.0 0.0 2.5 2 0 0 2 2 2 2 Flagellar C1a complex subunit C1a-32 PKcGMP_CC PF16808.5 CDJ88776.1 - 0.015 15.1 4.6 6.7 6.7 0.2 3.6 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HNOBA PF07701.14 CDJ88776.1 - 0.022 14.2 11.9 0.5 9.8 2.0 2.3 2 0 0 2 2 2 0 Heme NO binding associated Peptidase_S21 PF00716.17 CDJ88776.1 - 0.03 14.0 4.9 1.7 8.3 1.2 2.4 1 1 1 2 2 2 0 Assemblin (Peptidase family S21) RNA_pol_Rpb5_N PF03871.14 CDJ88776.1 - 0.042 14.4 0.7 20 5.8 0.0 2.9 3 0 0 3 3 3 0 RNA polymerase Rpb5, N-terminal domain IL11 PF07400.11 CDJ88776.1 - 0.11 12.1 1.6 11 5.7 0.1 2.3 2 0 0 2 2 2 0 Interleukin 11 Histone_HNS PF00816.21 CDJ88776.1 - 0.12 13.2 1.3 28 5.6 0.1 2.6 2 0 0 2 2 2 0 H-NS histone family Casc1_N PF15927.5 CDJ88776.1 - 0.33 10.6 10.7 1.7 8.3 0.9 2.4 2 1 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus U1snRNP70_N PF12220.8 CDJ88776.1 - 0.41 11.3 10.0 0.84 10.3 0.1 3.1 3 0 0 3 3 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal CHASE3 PF05227.13 CDJ88776.1 - 0.44 10.4 7.4 6 6.8 0.8 2.4 2 0 0 2 2 2 0 CHASE3 domain DUF16 PF01519.16 CDJ88776.1 - 0.52 10.8 3.0 23 5.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 PspB PF06667.12 CDJ88776.1 - 0.66 10.1 15.5 1.4 9.0 2.2 2.7 3 0 0 3 3 2 0 Phage shock protein B DUF2383 PF09537.10 CDJ88776.1 - 0.72 10.2 4.5 21 5.5 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) PRIMA1 PF16101.5 CDJ88776.1 - 1.3 9.1 7.4 10 6.2 0.8 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF2570 PF10828.8 CDJ88776.1 - 2.1 8.2 6.5 13 5.7 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) DDE_Tnp_1_6 PF13751.6 CDJ88776.1 - 3.3 8.0 6.7 20 5.4 0.7 2.3 2 0 0 2 2 2 0 Transposase DDE domain PLC-beta_C PF08703.10 CDJ88776.1 - 5.4 7.0 16.4 1.1 9.3 0.4 2.7 2 1 0 2 2 2 0 PLC-beta C terminal SlyX PF04102.12 CDJ88776.1 - 9.7 6.9 15.9 19 6.0 4.0 2.7 2 0 0 2 2 2 0 SlyX Frizzled PF01534.17 CDJ88777.1 - 1.7e-29 102.9 7.2 3e-29 102.1 7.2 1.3 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 CDJ88777.1 - 2.2e-29 102.3 2.2 4.8e-29 101.2 2.2 1.5 1 0 0 1 1 1 1 Fz domain DUF3488 PF11992.8 CDJ88777.1 - 0.12 11.3 6.4 0.15 11.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) MFP2b PF12150.8 CDJ88778.1 - 9.6e-88 294.7 1.3 2.1e-65 221.3 0.0 2.0 1 1 1 2 2 2 2 Cytosolic motility protein NUDIX PF00293.28 CDJ88779.1 - 3.4e-19 69.2 0.1 6.4e-19 68.3 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 CDJ88779.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Nucleotide hydrolase adh_short PF00106.25 CDJ88780.1 - 3.3e-30 105.0 0.0 4e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ88780.1 - 2.1e-17 63.5 0.0 2.5e-17 63.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ88780.1 - 0.0089 16.0 0.0 0.014 15.3 0.0 1.3 1 1 0 1 1 1 1 KR domain DENN PF02141.21 CDJ88780.1 - 0.069 13.1 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 DENN (AEX-3) domain Gcd10p PF04189.13 CDJ88781.1 - 9.8e-54 182.5 0.0 1.2e-53 182.2 0.0 1.0 1 0 0 1 1 1 1 Gcd10p family EMP70 PF02990.16 CDJ88782.1 - 1e-200 667.9 6.1 1e-200 667.9 6.1 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 TM2 PF05154.16 CDJ88783.1 - 0.00012 22.3 0.7 0.00012 22.3 0.7 2.9 3 0 0 3 3 3 1 TM2 domain DUF2530 PF10745.9 CDJ88783.1 - 0.095 13.0 4.4 1.7 9.0 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Homeobox_KN PF05920.11 CDJ88784.1 - 8.9e-10 38.3 0.1 2.7e-09 36.8 0.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CDJ88784.1 - 2.3e-07 30.5 0.7 2.3e-07 30.5 0.7 2.1 2 0 0 2 2 2 1 Homeodomain Homez PF11569.8 CDJ88784.1 - 4.6e-05 22.8 0.7 0.00044 19.7 0.0 2.8 3 0 0 3 3 3 1 Homeodomain leucine-zipper encoding, Homez PCEMA1 PF07418.11 CDJ88784.1 - 0.0081 15.7 0.4 0.014 14.9 0.4 1.3 1 0 0 1 1 1 1 Acidic phosphoprotein precursor PCEMA1 Dna2 PF08696.11 CDJ88784.1 - 0.096 12.5 0.0 0.096 12.5 0.0 2.1 3 0 0 3 3 3 0 DNA replication factor Dna2 MRP-S32 PF10210.9 CDJ88784.1 - 0.25 11.9 0.1 0.25 11.9 0.1 2.6 3 0 0 3 3 3 0 Mitochondrial 28S ribosomal protein S32 BLOC1S3 PF15753.5 CDJ88785.1 - 7.2e-05 23.0 1.9 0.07 13.3 0.6 2.1 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex 1 subunit 3 Pkinase_Tyr PF07714.17 CDJ88786.1 - 5.2e-29 101.3 0.1 7.3e-29 100.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ88786.1 - 3.7e-18 65.9 0.0 5.4e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HlyD_3 PF13437.6 CDJ88786.1 - 0.036 14.8 0.0 0.067 13.9 0.0 1.4 1 0 0 1 1 1 0 HlyD family secretion protein RVT_1 PF00078.27 CDJ88788.1 - 1.2e-15 57.6 0.0 1.6e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Methyltr_RsmF_N PF17125.5 CDJ88788.1 - 0.11 13.0 0.1 0.4 11.2 0.0 1.9 1 1 1 2 2 2 0 N-terminal domain of 16S rRNA methyltransferase RsmF CX PF01705.19 CDJ88789.1 - 8.7e-19 67.8 5.6 1.6e-18 66.9 5.6 1.5 1 0 0 1 1 1 1 CX module WBP-1 PF11669.8 CDJ88789.1 - 2.6 8.7 9.7 9.1 7.0 9.6 1.9 2 0 0 2 2 2 0 WW domain-binding protein 1 GST_C_6 PF17171.4 CDJ88790.1 - 1e-16 60.5 0.1 1.7e-16 59.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDJ88790.1 - 2.7e-10 40.1 0.0 3.9e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDJ88790.1 - 9.4e-07 29.0 0.0 1.5e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDJ88790.1 - 2.1e-05 24.6 0.0 3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.16 CDJ88791.1 - 8.7e-59 199.2 28.1 1.6e-56 191.8 22.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CDJ88791.1 - 1.3e-06 28.0 3.4 1.3e-06 28.0 3.4 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 CDJ88791.1 - 0.003 16.2 26.0 0.011 14.3 10.5 2.8 2 2 0 2 2 2 2 MFS/sugar transport protein DUF3624 PF12292.8 CDJ88791.1 - 0.81 10.1 0.0 0.81 10.1 0.0 4.4 7 0 0 7 7 7 0 Protein of unknown function (DUF3624) UBX PF00789.20 CDJ88793.1 - 2.6e-14 53.1 0.0 5.6e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain DUF966 PF06136.13 CDJ88793.1 - 0.094 12.4 6.9 0.14 11.8 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Hid1 PF12722.7 CDJ88793.1 - 1.4 7.0 5.9 1.8 6.6 5.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Endostatin PF06482.11 CDJ88793.1 - 1.5 8.2 5.8 2.3 7.6 5.8 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Macoilin PF09726.9 CDJ88793.1 - 7.2 5.0 14.7 9.7 4.6 14.7 1.1 1 0 0 1 1 1 0 Macoilin family FAM76 PF16046.5 CDJ88794.1 - 0.0033 16.8 5.1 0.0046 16.4 5.1 1.1 1 0 0 1 1 1 1 FAM76 protein zf-C2H2_2 PF12756.7 CDJ88794.1 - 0.056 13.8 1.3 0.095 13.0 0.3 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CDJ88794.1 - 0.074 13.4 3.0 0.44 10.9 3.0 2.2 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Imm5 PF14423.6 CDJ88794.1 - 0.53 10.5 6.8 1.1 9.4 6.8 1.4 1 0 0 1 1 1 0 Immunity protein Imm5 DUF1043 PF06295.12 CDJ88794.1 - 3.4 7.7 5.6 24 4.9 2.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) DUF1768 PF08719.11 CDJ88795.1 - 1.2e-28 100.3 0.0 1.8e-09 38.0 0.0 3.5 3 1 0 3 3 3 3 Domain of unknown function (DUF1768) Rota_NS53 PF00981.17 CDJ88795.1 - 0.058 12.3 0.3 8.8 5.1 0.0 2.2 2 0 0 2 2 2 0 Rotavirus RNA-binding Protein 53 (NS53) KH_2 PF07650.17 CDJ88796.1 - 7.6e-12 44.9 0.0 9.6e-12 44.6 0.0 1.1 1 0 0 1 1 1 1 KH domain Laminin_EGF PF00053.24 CDJ88798.1 - 7e-108 352.6 307.2 1.9e-12 47.1 13.9 16.2 15 1 1 16 16 16 15 Laminin EGF domain Laminin_N PF00055.17 CDJ88798.1 - 4.5e-70 235.9 0.0 4.5e-70 235.9 0.0 3.6 3 0 0 3 3 3 1 Laminin N-terminal (Domain VI) Laminin_B PF00052.18 CDJ88798.1 - 5.2e-33 113.8 0.1 5.5e-28 97.5 0.0 2.3 2 0 0 2 2 2 2 Laminin B (Domain IV) Helicase_C PF00271.31 CDJ88800.1 - 9.2e-30 103.3 2.8 2.2e-29 102.1 0.6 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ88800.1 - 4e-21 75.6 0.2 2e-20 73.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDJ88800.1 - 0.0071 16.6 0.1 0.035 14.4 0.1 2.2 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 CDJ88800.1 - 0.3 10.8 2.2 0.98 9.1 0.0 2.7 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family MFS_1 PF07690.16 CDJ88801.1 - 6e-17 61.6 21.5 4.5e-10 39.0 17.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_4_2 PF04020.13 CDJ88801.1 - 7.7 7.2 12.9 0.31 11.7 5.1 2.7 3 0 0 3 3 3 0 Mycobacterial 4 TMS phage holin, superfamily IV DEAD PF00270.29 CDJ88802.1 - 6.4e-24 84.7 0.7 4.7e-22 78.6 0.1 2.1 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 CDJ88802.1 - 7.4e-06 26.1 0.2 2.5e-05 24.4 0.0 1.9 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 CDJ88802.1 - 0.2 11.2 5.3 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain FOXP-CC PF16159.5 CDJ88803.1 - 0.00012 22.7 1.0 0.00028 21.5 1.0 1.6 1 0 0 1 1 1 1 FOXP coiled-coil domain DUF641 PF04859.12 CDJ88803.1 - 0.052 13.9 1.6 0.086 13.2 1.6 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) CREPT PF16566.5 CDJ88803.1 - 0.13 12.5 1.9 0.29 11.3 1.9 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Syntaxin-6_N PF09177.11 CDJ88803.1 - 0.19 12.3 1.4 0.37 11.4 1.4 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal CENP-H PF05837.12 CDJ88803.1 - 0.19 12.1 1.7 0.33 11.4 1.7 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) TMF_DNA_bd PF12329.8 CDJ88803.1 - 0.23 11.5 7.3 0.14 12.2 4.3 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HIP1_clath_bdg PF16515.5 CDJ88803.1 - 0.33 11.6 2.9 0.68 10.6 2.9 1.4 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Hydrolase_4 PF12146.8 CDJ88804.1 - 2.3e-13 50.0 0.0 1.8e-07 30.7 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ88804.1 - 3.4e-09 36.7 0.1 0.0019 17.9 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ88804.1 - 7.9e-08 33.2 1.6 1.1e-05 26.2 0.1 2.6 2 1 1 3 3 3 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CDJ88804.1 - 0.00013 21.6 0.0 0.015 14.8 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF818 PF05677.12 CDJ88804.1 - 0.00046 19.3 0.0 0.0031 16.5 0.0 1.9 2 0 0 2 2 2 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.16 CDJ88804.1 - 0.002 18.0 0.0 0.0055 16.5 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 CDJ88804.1 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 CDJ88804.1 - 0.004 16.8 0.0 0.0062 16.2 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Asp2 PF16929.5 CDJ88804.1 - 0.11 11.4 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter UPF0227 PF05728.12 CDJ88804.1 - 0.23 11.4 0.0 0.86 9.5 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) AAA PF00004.29 CDJ88805.1 - 5.9e-28 97.9 0.3 7.9e-21 74.9 0.0 2.8 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ88805.1 - 4.6e-16 58.3 0.1 8.1e-16 57.6 0.1 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CDJ88805.1 - 0.00077 19.9 0.1 0.0017 18.8 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CDJ88805.1 - 0.0012 18.9 0.4 0.16 12.0 0.0 2.8 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CDJ88805.1 - 0.0013 18.9 0.0 0.88 9.7 0.1 3.0 2 1 1 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDJ88805.1 - 0.05 13.9 0.0 0.089 13.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CDJ88805.1 - 0.07 12.5 0.0 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 CDJ88805.1 - 0.092 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain RuvB_N PF05496.12 CDJ88805.1 - 0.097 12.4 0.0 0.66 9.7 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Frizzled PF01534.17 CDJ88808.1 - 2.4e-97 325.9 20.0 3.3e-97 325.4 20.0 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 CDJ88808.1 - 6.4e-27 94.4 7.9 6.4e-27 94.4 7.9 1.9 2 0 0 2 2 2 1 Fz domain DUF1600 PF07667.11 CDJ88808.1 - 0.46 10.7 8.2 1.9 8.8 6.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1600) NatB_MDM20 PF09797.9 CDJ88810.1 - 6.3e-61 206.4 0.0 8.4e-61 206.0 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit EAP30 PF04157.16 CDJ88810.1 - 0.0022 17.3 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 EAP30/Vps36 family TPR_14 PF13428.6 CDJ88812.1 - 0.0052 17.5 0.0 6.7 7.8 0.0 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat Mcl1_mid PF12341.8 CDJ88812.1 - 0.041 13.2 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region TPR_16 PF13432.6 CDJ88812.1 - 0.1 13.3 0.0 0.21 12.3 0.0 1.5 2 0 0 2 2 2 0 Tetratricopeptide repeat LUC7 PF03194.15 CDJ88813.1 - 7e-70 235.6 13.6 8.9e-70 235.2 13.6 1.1 1 0 0 1 1 1 1 LUC7 N_terminus fn3 PF00041.21 CDJ88814.1 - 6.4e-12 45.6 0.0 1.3e-05 25.5 0.0 3.6 3 1 0 3 3 3 3 Fibronectin type III domain DHR10 PF18595.1 CDJ88814.1 - 0.35 10.9 7.0 0.72 9.9 7.0 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain TB2_DP1_HVA22 PF03134.19 CDJ88815.1 - 1.2e-23 82.9 5.8 1.2e-23 82.9 5.8 1.7 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Transcrip_act PF04949.13 CDJ88815.1 - 0.064 13.1 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Transcriptional activator Macoilin PF09726.9 CDJ88815.1 - 1.4 7.4 5.4 1.6 7.2 5.4 1.2 1 0 0 1 1 1 0 Macoilin family Zwilch PF09817.9 CDJ88816.1 - 1.3e-07 30.5 0.0 1.6e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 RZZ complex, subunit zwilch GDNF PF02351.16 CDJ88817.1 - 0.0042 18.0 14.9 0.0042 18.0 14.9 2.5 2 0 0 2 2 2 2 GDNF/GAS1 domain Asp PF00026.23 CDJ88818.1 - 1.4e-89 300.7 3.6 1.7e-89 300.4 3.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ88818.1 - 4.4e-11 43.3 5.5 4.4e-11 43.3 5.5 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ88818.1 - 4.6e-05 23.3 0.0 0.00015 21.6 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CDJ88818.1 - 0.0017 19.0 0.1 1.7 9.3 0.0 3.1 3 0 0 3 3 3 2 Aspartyl protease YqfD PF06898.11 CDJ88818.1 - 0.17 10.7 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD GDNF PF02351.16 CDJ88819.1 - 1.9e-07 32.0 25.5 1.7e-06 28.9 5.6 2.6 2 0 0 2 2 2 2 GDNF/GAS1 domain YdaT_toxin PF06254.11 CDJ88820.1 - 0.042 14.4 0.1 0.2 12.2 0.0 2.0 2 0 0 2 2 2 0 Putative bacterial toxin ydaT Pox_A14 PF05767.12 CDJ88820.1 - 0.084 13.0 0.9 0.24 11.6 0.6 2.0 1 1 0 1 1 1 0 Poxvirus virion envelope protein A14 CBM9_2 PF16011.5 CDJ88821.1 - 0.098 12.3 0.7 6.2 6.5 0.7 2.2 1 1 0 1 1 1 0 Carbohydrate-binding family 9 7TM_GPCR_Srv PF10323.9 CDJ88823.1 - 9e-07 28.5 0.3 1.2e-06 28.1 0.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv CFC PF09443.10 CDJ88823.1 - 0.069 13.0 1.9 0.13 12.1 1.9 1.4 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) HTH_Tnp_Tc3_2 PF01498.18 CDJ88825.1 - 2.1e-23 82.4 0.8 3.8e-23 81.5 0.8 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 CDJ88825.1 - 4.2e-08 33.1 0.1 8.8e-08 32.0 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 CDJ88825.1 - 1.1e-05 26.0 0.7 1.1e-05 26.0 0.7 2.7 3 0 0 3 3 3 1 Homeodomain-like domain PAX PF00292.18 CDJ88825.1 - 0.00022 21.2 0.2 0.00035 20.5 0.2 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_24 PF13412.6 CDJ88825.1 - 0.0024 17.4 1.9 0.064 12.8 1.9 2.3 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 CDJ88825.1 - 0.2 11.4 0.3 11 5.8 0.0 2.7 3 0 0 3 3 3 0 Sigma-70, region 4 Lamp PF01299.17 CDJ88826.1 - 5.6e-07 29.5 1.0 5e-06 26.4 1.0 2.3 1 1 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) ATP-synt_S1 PF05827.12 CDJ88826.1 - 0.053 13.4 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) Syndecan PF01034.20 CDJ88826.1 - 0.24 11.3 0.9 0.43 10.5 0.9 1.3 1 0 0 1 1 1 0 Syndecan domain Peptidase_C1 PF00112.23 CDJ88828.1 - 1.1e-61 208.7 11.3 1.5e-61 208.3 11.3 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ88828.1 - 0.15 10.8 5.3 0.13 11.0 0.9 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ88829.1 - 8.8e-63 212.3 10.0 1.2e-62 211.9 10.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ88829.1 - 0.021 13.6 4.0 0.041 12.7 0.8 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ88830.1 - 5e-60 203.3 13.1 7.4e-60 202.7 13.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ88830.1 - 0.064 12.0 3.0 0.55 8.9 0.9 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Conotoxin_I2 PF17557.2 CDJ88830.1 - 1.7 8.9 8.4 16 5.7 0.2 3.2 3 0 0 3 3 3 0 I2-superfamily conotoxins HTH_29 PF13551.6 CDJ88831.1 - 8.6e-08 32.1 0.9 1.8e-06 27.9 0.1 2.5 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 CDJ88831.1 - 5.4e-07 29.2 0.3 0.00098 18.9 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 CDJ88831.1 - 6.6e-07 29.4 0.5 0.0089 16.1 0.1 3.3 3 0 0 3 3 3 2 Helix-turn-helix domain DUF4423 PF14394.6 CDJ88831.1 - 0.00019 21.2 2.0 0.00032 20.5 0.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4423) MarR_2 PF12802.7 CDJ88831.1 - 0.00035 20.4 0.4 0.068 13.1 0.1 2.4 2 0 0 2 2 2 1 MarR family HTH_psq PF05225.16 CDJ88831.1 - 0.0007 19.3 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_38 PF13936.6 CDJ88831.1 - 0.0014 18.3 0.6 1.6 8.6 0.1 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_32 PF13565.6 CDJ88831.1 - 0.0015 19.1 3.8 0.0021 18.7 1.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 CDJ88831.1 - 0.0027 17.9 2.5 0.017 15.4 1.0 2.5 2 0 0 2 2 2 1 Transposase HTH_Crp_2 PF13545.6 CDJ88831.1 - 0.004 17.1 1.7 0.028 14.4 0.1 2.6 3 0 0 3 3 3 1 Crp-like helix-turn-helix domain MarR PF01047.22 CDJ88831.1 - 0.0065 16.4 0.2 1.3 9.0 0.0 2.5 2 0 0 2 2 2 1 MarR family HTH_11 PF08279.12 CDJ88831.1 - 0.016 15.2 0.4 3 7.9 0.0 2.6 2 0 0 2 2 2 0 HTH domain CENP-B_N PF04218.13 CDJ88831.1 - 0.016 14.9 0.6 3 7.6 0.1 2.7 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_24 PF13412.6 CDJ88831.1 - 0.021 14.4 0.8 6.2 6.5 0.1 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 CDJ88831.1 - 0.037 13.9 0.9 0.51 10.3 0.1 2.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_35 PF13693.6 CDJ88831.1 - 0.037 14.1 0.2 3.5 7.7 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 CDJ88831.1 - 0.039 13.5 3.3 0.87 9.2 0.1 3.2 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_AsnC-type PF13404.6 CDJ88831.1 - 0.063 13.1 0.1 0.73 9.7 0.0 2.5 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain DDE_3 PF13358.6 CDJ88831.1 - 0.087 12.6 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_Tnp_IS630 PF01710.16 CDJ88831.1 - 0.4 10.8 8.4 0.26 11.3 5.9 2.1 2 1 0 2 2 2 0 Transposase Peptidase_C1 PF00112.23 CDJ88832.1 - 1.9e-60 204.7 10.5 2.9e-60 204.1 10.5 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ88832.1 - 0.0035 16.2 2.0 0.034 12.9 0.6 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ88833.1 - 3e-62 210.6 9.9 3.9e-62 210.2 9.9 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ88833.1 - 0.0033 16.2 3.3 0.032 13.0 0.9 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ88834.1 - 3.8e-65 220.0 13.8 5.1e-65 219.6 13.8 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ88834.1 - 0.0022 16.9 2.3 0.055 12.2 1.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ88835.1 - 2.7e-58 197.6 9.6 4.1e-58 197.1 9.6 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ88835.1 - 0.26 10.0 5.0 0.28 9.9 1.2 2.0 2 0 0 2 2 2 0 Peptidase C1-like family Conotoxin_I2 PF17557.2 CDJ88835.1 - 1.1 9.5 7.1 16 5.7 0.2 2.7 2 0 0 2 2 2 0 I2-superfamily conotoxins Peptidase_C1 PF00112.23 CDJ88836.1 - 5.1e-62 209.8 11.8 6.9e-62 209.4 11.8 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ88836.1 - 0.0067 15.3 1.8 0.23 10.2 0.4 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Conotoxin_I2 PF17557.2 CDJ88836.1 - 6.3 7.0 11.1 6.6 6.9 1.8 3.1 3 0 0 3 3 3 0 I2-superfamily conotoxins Peptidase_C1 PF00112.23 CDJ88837.1 - 2.8e-47 161.6 6.5 3.8e-47 161.2 6.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ88837.1 - 0.0082 15.0 0.6 0.011 14.5 0.6 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Conotoxin_I2 PF17557.2 CDJ88837.1 - 0.03 14.4 5.8 1.5 9.0 0.1 2.6 2 0 0 2 2 2 0 I2-superfamily conotoxins Peptidase_C1 PF00112.23 CDJ88838.1 - 2.4e-58 197.8 9.2 3.1e-58 197.4 9.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ88838.1 - 1 8.1 3.1 4 6.1 1.0 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ88839.1 - 9.1e-59 199.2 11.6 1.2e-58 198.8 11.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ88839.1 - 0.32 9.7 4.1 0.77 8.5 0.9 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ88840.1 - 5.8e-64 216.2 9.2 7.4e-64 215.8 9.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ88840.1 - 0.011 14.6 2.9 0.056 12.2 0.6 2.0 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ88841.1 - 3.1e-30 105.9 11.6 4.5e-17 62.9 3.9 2.3 1 1 1 2 2 2 2 Papain family cysteine protease ABC_tran_Xtn PF12848.7 CDJ88841.1 - 0.048 13.7 1.7 1.5 8.9 0.8 2.2 2 0 0 2 2 2 0 ABC transporter Peptidase_C1_2 PF03051.15 CDJ88841.1 - 0.33 9.7 5.2 3.2 6.4 1.9 2.1 1 1 1 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ88842.1 - 0.058 13.5 0.2 0.11 12.6 0.0 1.5 2 0 0 2 2 2 0 Papain family cysteine protease Peptidase_C1 PF00112.23 CDJ88843.1 - 1.2e-61 208.6 7.9 1.8e-61 208.0 7.9 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ88843.1 - 0.00068 18.5 4.1 0.022 13.5 0.6 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ88844.1 - 1.6e-62 211.5 12.6 2.4e-62 210.9 12.6 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ88844.1 - 0.0012 17.7 4.3 0.01 14.6 0.9 2.3 2 0 0 2 2 2 2 Peptidase C1-like family DUF4437 PF14499.6 CDJ88844.1 - 0.031 13.4 0.1 0.075 12.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4437) Peptidase_C1 PF00112.23 CDJ88845.1 - 6.1e-48 163.8 4.7 7.1e-48 163.6 4.7 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ88845.1 - 0.0072 15.1 1.1 0.011 14.6 1.1 1.2 1 0 0 1 1 1 1 Peptidase C1-like family Pkinase PF00069.25 CDJ88846.1 - 0.0075 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Lipase_3 PF01764.25 CDJ88847.1 - 1.3e-35 122.3 0.0 1.9e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CDJ88847.1 - 0.0035 18.0 0.0 0.0075 16.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 CDJ88847.1 - 0.028 14.0 0.1 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF2048 PF09752.9 CDJ88847.1 - 0.031 13.4 0.0 0.064 12.3 0.0 1.5 2 0 0 2 2 2 0 Abhydrolase domain containing 18 Abhydrolase_1 PF00561.20 CDJ88847.1 - 0.065 12.9 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 CDJ88847.1 - 0.066 13.0 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 CDJ88847.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 CDJ88847.1 - 0.084 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 CDJ88847.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.5 1 1 0 1 1 1 0 PGAP1-like protein DUF4231 PF14015.6 CDJ88848.1 - 0.00034 21.0 0.0 0.00061 20.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4231) Sarcoglycan_2 PF05510.13 CDJ88848.1 - 0.00097 18.0 0.1 0.0014 17.5 0.1 1.2 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon DUF3377 PF11857.8 CDJ88848.1 - 0.013 15.4 0.2 0.038 13.9 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF3974 PF13120.6 CDJ88848.1 - 0.026 14.6 0.1 0.043 13.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) DUF4381 PF14316.6 CDJ88848.1 - 0.039 14.2 0.8 0.074 13.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Protocadherin PF08374.11 CDJ88848.1 - 0.04 13.9 0.0 0.072 13.1 0.0 1.4 1 1 0 1 1 1 0 Protocadherin TMEM154 PF15102.6 CDJ88849.1 - 9.8e-06 25.5 2.6 9.8e-06 25.5 2.6 1.8 1 1 1 2 2 2 1 TMEM154 protein family Glycophorin_A PF01102.18 CDJ88849.1 - 8.9e-05 22.7 0.1 0.00018 21.8 0.1 1.5 1 0 0 1 1 1 1 Glycophorin A DUF5305 PF17231.2 CDJ88849.1 - 0.00045 19.7 2.8 0.00065 19.2 2.8 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5305) DUF2207 PF09972.9 CDJ88849.1 - 0.0049 15.7 0.2 0.0071 15.2 0.2 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) EVI2A PF05399.11 CDJ88849.1 - 0.0082 15.8 0.5 0.0082 15.8 0.5 1.5 1 1 0 1 1 1 1 Ectropic viral integration site 2A protein (EVI2A) Dicty_REP PF05086.12 CDJ88849.1 - 0.026 12.5 1.8 0.028 12.4 1.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4834 PF16118.5 CDJ88849.1 - 0.045 14.7 1.8 1.1 10.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) V_ATPase_I PF01496.19 CDJ88849.1 - 0.063 11.2 0.1 0.074 11.0 0.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Stevor PF17410.2 CDJ88849.1 - 0.076 12.5 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Peptidase_M56 PF05569.11 CDJ88849.1 - 0.1 11.8 0.2 0.13 11.4 0.2 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 TMEM132D_C PF15706.5 CDJ88849.1 - 0.12 12.1 0.2 0.31 10.9 0.2 1.6 1 1 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term LST1 PF05083.13 CDJ88849.1 - 0.13 12.5 2.1 0.37 11.1 2.1 1.9 1 1 0 1 1 1 0 LST-1 protein Orf78 PF06024.12 CDJ88849.1 - 0.15 12.3 0.3 0.37 11.1 0.0 1.8 2 0 0 2 2 2 0 Orf78 (ac78) AJAP1_PANP_C PF15298.6 CDJ88849.1 - 0.17 12.1 8.4 0.28 11.4 8.4 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus MGC-24 PF05283.11 CDJ88849.1 - 0.2 12.1 6.2 0.053 14.0 2.9 1.7 2 0 0 2 2 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3439 PF11921.8 CDJ88849.1 - 0.7 9.9 17.4 0.031 14.2 11.9 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 CDJ88849.1 - 1.1 7.4 17.2 0.013 13.7 10.1 1.4 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 LapA_dom PF06305.11 CDJ88849.1 - 1.5 8.6 3.2 4.2 7.3 3.2 1.7 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain TMEM100 PF16311.5 CDJ88849.1 - 2.1 7.9 6.7 0.51 9.9 1.0 2.3 1 1 1 2 2 2 0 Transmembrane protein 100 TMEM132D_C PF15706.5 CDJ88850.1 - 0.019 14.8 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term V_ATPase_I PF01496.19 CDJ88850.1 - 0.027 12.4 0.0 0.035 12.1 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMEM100 PF16311.5 CDJ88850.1 - 0.085 12.4 0.1 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 Transmembrane protein 100 Amnionless PF14828.6 CDJ88850.1 - 0.13 11.0 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Amnionless Hid1 PF12722.7 CDJ88850.1 - 0.19 9.8 0.0 0.26 9.4 0.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LapA_dom PF06305.11 CDJ88850.1 - 0.36 10.7 4.2 1.1 9.2 4.2 1.8 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Prenyltrans PF00432.21 CDJ88851.1 - 2.1e-26 91.3 6.5 5.1e-09 35.7 0.0 6.3 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat WASH_WAHD PF11945.8 CDJ88851.1 - 3e-22 79.5 0.0 4.8e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 WAHD domain of WASH complex WH2 PF02205.20 CDJ88851.1 - 0.00088 19.0 8.4 0.0038 17.0 0.3 3.7 3 0 0 3 3 3 1 WH2 motif CAP_N PF01213.19 CDJ88851.1 - 0.0028 17.2 9.1 0.0028 17.2 9.1 1.6 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal FeS PF04060.13 CDJ88851.1 - 0.38 10.4 1.1 0.85 9.3 1.1 1.6 1 0 0 1 1 1 0 Putative Fe-S cluster Mito_fiss_reg PF05308.11 CDJ88851.1 - 0.42 10.7 8.1 1.6 8.8 7.4 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator PIG-P PF08510.12 CDJ88852.1 - 3.2e-21 75.5 2.6 3.5e-21 75.4 2.6 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 CDJ88852.1 - 0.0034 17.6 10.0 0.0049 17.1 10.0 1.2 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Claudin_3 PF06653.11 CDJ88852.1 - 0.0076 16.2 1.2 0.0093 15.9 1.2 1.0 1 0 0 1 1 1 1 Tight junction protein, Claudin-like DUF5084 PF16894.5 CDJ88852.1 - 0.01 16.2 5.2 0.017 15.6 5.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5084) DPM3 PF08285.11 CDJ88852.1 - 0.28 11.4 4.8 0.39 10.9 4.8 1.2 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) MMR_HSR1 PF01926.23 CDJ88853.1 - 1.2e-08 35.0 0.0 9.7e-08 32.1 0.0 2.5 3 1 0 3 3 3 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CDJ88853.1 - 0.0035 17.4 0.0 0.011 15.8 0.0 2.0 2 1 0 2 2 2 1 Dynamin family FeoB_N PF02421.18 CDJ88853.1 - 0.019 14.5 0.0 0.13 11.8 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CDJ88853.1 - 0.042 13.7 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase PXA PF02194.15 CDJ88854.1 - 6.3e-27 94.7 0.7 2.3e-26 92.9 0.7 2.0 1 0 0 1 1 1 1 PXA domain PX PF00787.24 CDJ88854.1 - 8e-14 51.6 0.8 8e-14 51.6 0.8 2.1 2 0 0 2 2 2 1 PX domain RGS PF00615.19 CDJ88854.1 - 2e-08 34.5 6.0 2.8e-08 34.1 0.9 3.0 3 0 0 3 3 3 1 Regulator of G protein signaling domain Nexin_C PF08628.12 CDJ88854.1 - 0.025 15.1 0.1 0.11 13.1 0.0 2.2 2 0 0 2 2 2 0 Sorting nexin C terminal Transglut_i_TM PF14400.6 CDJ88854.1 - 0.087 12.9 0.7 0.32 11.1 0.0 2.2 3 0 0 3 3 3 0 Inactive transglutaminase fused to 7 transmembrane helices DDE_3 PF13358.6 CDJ88856.1 - 3.7e-11 43.0 0.0 4.9e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease TerB PF05099.13 CDJ88856.1 - 0.079 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TerB Lustrin_cystein PF14625.6 CDJ88857.1 - 1.7e-57 191.5 163.0 1.7e-08 34.7 5.6 14.2 14 1 0 14 14 14 11 Lustrin, cysteine-rich repeated domain Kunitz_BPTI PF00014.23 CDJ88857.1 - 2.4e-22 78.9 20.4 5.9e-16 58.5 7.4 3.6 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain EB PF01683.18 CDJ88857.1 - 3.9e-10 39.8 13.3 3.9e-10 39.8 13.3 9.9 8 4 0 8 8 8 3 EB module Pep3_Vps18 PF05131.14 CDJ88859.1 - 5.3e-27 94.5 0.0 1.4e-26 93.1 0.0 1.8 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 CDJ88859.1 - 1.8e-14 53.8 1.8 1.1e-11 44.7 0.0 3.5 4 0 0 4 4 4 2 Region in Clathrin and VPS Vps39_2 PF10367.9 CDJ88859.1 - 0.00014 22.3 0.8 0.00032 21.1 0.8 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 TPR_19 PF14559.6 CDJ88859.1 - 0.0003 21.2 1.6 0.00056 20.4 0.6 2.1 2 0 0 2 2 1 1 Tetratricopeptide repeat zf-C3H2C3 PF17122.5 CDJ88859.1 - 0.01 15.8 2.4 0.01 15.8 2.4 2.8 3 0 0 3 3 3 0 Zinc-finger Zn_ribbon_17 PF17120.5 CDJ88859.1 - 0.016 14.8 1.6 0.059 13.0 1.6 1.9 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DNA_ligase_OB PF03120.16 CDJ88859.1 - 0.16 11.9 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent DNA ligase OB-fold domain zf-RING_UBOX PF13445.6 CDJ88859.1 - 0.25 11.4 1.6 0.97 9.5 1.6 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 CDJ88859.1 - 0.81 10.1 9.0 0.38 11.1 3.9 2.8 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 CDJ88859.1 - 1 9.4 9.2 0.071 13.1 2.5 2.4 2 0 0 2 2 2 0 zinc-RING finger domain DUF2570 PF10828.8 CDJ88859.1 - 1.8 8.5 4.7 5 7.0 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) TPR_14 PF13428.6 CDJ88859.1 - 6.9 7.8 6.7 3.6 8.7 0.1 3.8 4 1 1 5 5 3 0 Tetratricopeptide repeat AAA_18 PF13238.6 CDJ88860.1 - 2.7e-30 105.6 0.0 4.6e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CDJ88860.1 - 5.9e-07 30.0 0.0 1.4e-06 28.7 0.0 1.7 2 1 0 2 2 1 1 AAA domain MRP_L53 PF10780.9 CDJ88860.1 - 1.1e-05 25.5 0.0 1.9e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 AAA_16 PF13191.6 CDJ88860.1 - 4.8e-05 23.8 0.1 0.00012 22.6 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 CDJ88860.1 - 9.6e-05 22.7 0.0 0.00024 21.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDJ88860.1 - 0.00011 22.4 0.1 0.0064 16.7 0.0 2.6 2 1 1 3 3 2 1 AAA domain AAA_22 PF13401.6 CDJ88860.1 - 0.00017 21.8 0.0 0.00058 20.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 CDJ88860.1 - 0.00021 21.2 0.0 0.00061 19.7 0.0 1.9 2 0 0 2 2 1 1 NTPase AAA PF00004.29 CDJ88860.1 - 0.00024 21.6 0.0 0.0005 20.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 CDJ88860.1 - 0.00096 18.9 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase MCM PF00493.23 CDJ88860.1 - 0.0012 17.9 0.0 0.0082 15.3 0.0 2.0 2 0 0 2 2 2 1 MCM P-loop domain AAA_5 PF07728.14 CDJ88860.1 - 0.0018 18.2 0.0 0.005 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) KTI12 PF08433.10 CDJ88860.1 - 0.0042 16.6 0.0 0.0085 15.6 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 SKI PF01202.22 CDJ88860.1 - 0.0044 17.1 0.0 0.048 13.8 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase ATPase PF06745.13 CDJ88860.1 - 0.01 15.2 0.0 0.032 13.6 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_29 PF13555.6 CDJ88860.1 - 0.011 15.5 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 CDJ88860.1 - 0.011 15.4 0.0 0.03 14.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain DUF2075 PF09848.9 CDJ88860.1 - 0.014 14.7 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CDJ88860.1 - 0.015 15.3 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 CDJ88860.1 - 0.016 15.6 0.0 0.048 14.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.18 CDJ88860.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Cytidylate_kin2 PF13189.6 CDJ88860.1 - 0.02 15.0 0.2 0.092 12.9 0.1 2.2 2 1 0 2 2 1 0 Cytidylate kinase-like family MeaB PF03308.16 CDJ88860.1 - 0.024 13.6 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 CDJ88860.1 - 0.024 14.4 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SSE PF00437.20 CDJ88860.1 - 0.027 13.5 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ADK PF00406.22 CDJ88860.1 - 0.031 14.4 0.0 0.45 10.6 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase Zeta_toxin PF06414.12 CDJ88860.1 - 0.045 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.21 CDJ88860.1 - 0.051 12.9 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 CDJ88860.1 - 0.053 12.7 0.0 0.099 11.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 CDJ88860.1 - 0.054 13.0 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 CDJ88860.1 - 0.058 12.7 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.6 CDJ88860.1 - 0.062 13.6 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 CDJ88860.1 - 0.066 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase RuvB_N PF05496.12 CDJ88860.1 - 0.073 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 CDJ88860.1 - 0.1 12.0 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein Sigma54_activat PF00158.26 CDJ88860.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 CDJ88860.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Baculo_gp41 PF04700.12 CDJ88860.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region dNK PF01712.19 CDJ88860.1 - 0.15 11.9 0.2 14 5.5 0.0 2.2 1 1 0 2 2 2 0 Deoxynucleoside kinase AAA_30 PF13604.6 CDJ88860.1 - 0.17 11.6 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain RLL PF10036.9 CDJ88861.1 - 6.4e-38 131.1 5.0 7.7e-38 130.8 5.0 1.0 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein PseudoU_synth_1 PF01416.20 CDJ88862.1 - 1.3e-28 99.6 0.0 2.2e-27 95.6 0.0 2.3 2 0 0 2 2 2 1 tRNA pseudouridine synthase RVT_1 PF00078.27 CDJ88863.1 - 0.00094 18.8 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TetR_C_11 PF16859.5 CDJ88863.1 - 0.13 12.6 4.5 0.061 13.6 1.1 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain RVT_1 PF00078.27 CDJ88864.1 - 5.6e-24 84.9 0.0 9.4e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7TM_GPCR_Srab PF10292.9 CDJ88865.1 - 0.005 15.8 0.1 0.0066 15.4 0.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor DUF5641 PF18701.1 CDJ88867.1 - 4e-19 68.6 0.8 1e-18 67.3 0.8 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5641) Phlebovirus_G2 PF07245.11 CDJ88867.1 - 3.7e-09 35.6 5.2 5.4e-09 35.1 5.2 1.2 1 0 0 1 1 1 1 Phlebovirus glycoprotein G2 rve_3 PF13683.6 CDJ88867.1 - 5.5e-05 22.9 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RepB_primase PF16793.5 CDJ88867.1 - 0.03 14.4 0.1 0.048 13.8 0.1 1.3 1 0 0 1 1 1 0 RepB DNA-primase from phage plasmid Voltage_CLC PF00654.20 CDJ88868.1 - 1.1e-78 265.0 23.4 1.4e-78 264.6 23.4 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 CDJ88868.1 - 2.8e-10 40.5 0.1 0.0002 21.7 0.0 3.6 3 0 0 3 3 3 2 CBS domain Atthog PF18800.1 CDJ88868.1 - 0.0075 16.2 1.0 0.0075 16.2 1.0 2.3 2 0 0 2 2 2 1 Attenuator of Hedgehog Globin PF00042.22 CDJ88869.1 - 4.1e-07 30.5 0.0 9.2e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Globin BCDHK_Adom3 PF10436.9 CDJ88869.1 - 0.072 12.9 0.0 0.086 12.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Angiomotin_C PF12240.8 CDJ88870.1 - 0.0048 16.5 2.7 0.0059 16.2 2.7 1.2 1 0 0 1 1 1 1 Angiomotin C terminal CCDC53 PF10152.9 CDJ88872.1 - 0.11 12.9 1.3 0.14 12.5 1.3 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Lactamase_B PF00753.27 CDJ88872.1 - 0.32 11.0 3.8 0.45 10.5 3.8 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Tat PF00539.18 CDJ88875.1 - 8 6.7 11.5 2.3 8.5 7.5 2.3 1 1 1 2 2 2 0 Transactivating regulatory protein (Tat) DUF4605 PF15378.6 CDJ88876.1 - 8.1e-06 25.6 0.2 1.9e-05 24.4 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4605) 60KD_IMP PF02096.20 CDJ88876.1 - 0.00029 20.8 0.5 0.00055 19.9 0.5 1.5 1 0 0 1 1 1 1 60Kd inner membrane protein Cation_ATPase_N PF00690.26 CDJ88876.1 - 0.037 13.7 0.7 2.5 7.9 0.7 2.9 2 1 0 2 2 2 0 Cation transporter/ATPase, N-terminus Ldl_recept_a PF00057.18 CDJ88877.1 - 3e-08 33.7 13.2 3e-08 33.7 13.2 2.2 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A PAN_1 PF00024.26 CDJ88877.1 - 5.9e-07 29.4 0.3 1.9e-06 27.7 0.3 2.0 1 0 0 1 1 1 1 PAN domain SRCR_2 PF15494.6 CDJ88877.1 - 2.7e-06 27.8 0.5 0.00011 22.7 0.1 2.3 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain SRCR PF00530.18 CDJ88877.1 - 0.0065 16.9 0.1 0.0065 16.9 0.1 2.6 3 1 0 3 3 3 1 Scavenger receptor cysteine-rich domain Trypsin PF00089.26 CDJ88879.1 - 1.1e-56 192.1 0.0 1.1e-56 192.1 0.0 1.4 2 0 0 2 2 2 1 Trypsin Ldl_recept_a PF00057.18 CDJ88879.1 - 5.3e-08 32.9 8.3 5.3e-08 32.9 8.3 2.6 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A SRCR PF00530.18 CDJ88879.1 - 7.9e-06 26.3 0.9 1.6e-05 25.4 0.1 1.9 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain DUF1986 PF09342.11 CDJ88879.1 - 0.0009 19.6 0.0 0.0015 18.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) SRCR_2 PF15494.6 CDJ88879.1 - 0.016 15.8 0.4 0.04 14.4 0.0 1.9 1 1 1 2 2 2 0 Scavenger receptor cysteine-rich domain Trypsin_2 PF13365.6 CDJ88879.1 - 0.045 14.7 0.0 0.091 13.7 0.0 1.5 1 1 0 1 1 1 0 Trypsin-like peptidase domain zf-C2H2_12 PF18658.1 CDJ88880.1 - 0.78 9.4 2.6 2.2 7.9 2.6 1.7 1 0 0 1 1 1 0 Zinc-finger C2H2-type IQ PF00612.27 CDJ88881.1 - 1.1e-15 55.8 52.8 0.0034 17.0 0.3 8.7 9 0 0 9 9 9 7 IQ calmodulin-binding motif CH PF00307.31 CDJ88881.1 - 1.1e-05 25.5 0.0 4.8e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Calponin homology (CH) domain DUF1759 PF03564.15 CDJ88882.1 - 2.9e-22 79.2 2.1 3e-21 75.9 0.1 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF1759) PI_PP_C PF18365.1 CDJ88882.1 - 0.031 14.2 2.5 0.088 12.8 0.1 2.4 2 0 0 2 2 2 0 Phosphoinositide phosphatase C-terminal domain DUF2009 PF09418.10 CDJ88882.1 - 0.09 11.8 4.9 2 7.4 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2009) PepX_N PF09168.10 CDJ88882.1 - 0.21 12.0 3.0 1.6 9.1 1.0 2.3 2 0 0 2 2 2 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal SOGA PF11365.8 CDJ88882.1 - 0.33 12.1 4.5 0.72 11.0 3.9 1.9 1 1 0 1 1 1 0 Protein SOGA DUF4541 PF15074.6 CDJ88882.1 - 0.34 11.5 3.0 0.19 12.3 0.4 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4541) Pro_CA PF00484.19 CDJ88882.1 - 0.36 11.1 1.1 0.77 10.0 0.3 1.9 2 0 0 2 2 2 0 Carbonic anhydrase Fib_alpha PF08702.10 CDJ88882.1 - 0.78 9.9 9.9 0.38 10.9 3.2 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Occludin_ELL PF07303.13 CDJ88882.1 - 4.3 8.1 9.1 1.4 9.7 1.4 3.4 3 2 1 4 4 4 0 Occludin homology domain Peptidase_A17 PF05380.13 CDJ88883.1 - 4.9e-39 133.9 0.2 8.5e-39 133.2 0.2 1.4 1 0 0 1 1 1 1 Pao retrotransposon peptidase RVT_1 PF00078.27 CDJ88883.1 - 1e-09 38.2 0.0 2.4e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDJ88883.1 - 0.0089 16.0 0.0 0.026 14.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ88883.1 - 0.009 16.3 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RL11D PF11088.8 CDJ88883.1 - 0.013 15.7 0.0 0.18 12.1 0.0 2.4 2 0 0 2 2 2 0 Glycoprotein encoding membrane proteins RL5A and RL6 RNase_H PF00075.24 CDJ88883.1 - 0.037 14.2 0.0 0.32 11.1 0.0 2.2 1 1 1 2 2 2 0 RNase H RuvA_C PF07499.13 CDJ88884.1 - 0.2 12.1 0.0 0.24 11.9 0.0 1.1 1 0 0 1 1 1 0 RuvA, C-terminal domain MFS_1_like PF12832.7 CDJ88885.1 - 7.6e-63 212.7 11.1 9.7e-63 212.3 11.1 1.0 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 CDJ88885.1 - 5.1e-17 61.8 19.1 2.1e-12 46.6 19.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 CDJ88885.1 - 1.4e-12 47.3 15.2 8e-10 38.3 7.2 2.4 3 0 0 3 3 3 2 Nucleoside H+ symporter LacY_symp PF01306.19 CDJ88885.1 - 0.0011 17.9 8.0 0.0054 15.6 0.0 2.2 2 0 0 2 2 2 1 LacY proton/sugar symporter MFS_2 PF13347.6 CDJ88885.1 - 0.0033 16.0 18.5 0.0035 16.0 5.9 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.13 CDJ88885.1 - 0.059 11.8 9.0 0.092 11.1 9.0 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector CPP1-like PF11833.8 CDJ88885.1 - 0.34 10.5 3.0 0.66 9.6 0.0 2.5 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like MarR_2 PF12802.7 CDJ88886.1 - 0.028 14.3 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.10 CDJ88886.1 - 0.047 13.5 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_23 PF13384.6 CDJ88886.1 - 0.083 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Peptidase_C1 PF00112.23 CDJ88889.1 - 2.6e-75 253.2 4.4 3.3e-75 252.9 0.5 2.1 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CDJ88889.1 - 1.6e-14 54.1 0.2 4.6e-14 52.6 0.2 1.8 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Cystatin PF00031.21 CDJ88889.1 - 1.7e-09 37.8 0.1 3e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 Cystatin domain Peptidase_C1_2 PF03051.15 CDJ88889.1 - 5.2e-05 22.2 1.2 0.0066 15.3 0.1 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Cathelicidins PF00666.17 CDJ88889.1 - 0.013 15.8 0.5 0.031 14.6 0.5 1.6 1 0 0 1 1 1 0 Cathelicidin NARG2_C PF10505.9 CDJ88890.1 - 9.2e-06 25.3 0.0 2.5e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus Ribosomal_L7Ae PF01248.26 CDJ88891.1 - 2.3e-20 72.1 0.1 4.3e-20 71.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family AMPK1_CBM PF16561.5 CDJ88891.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase Malate_DH PF12434.8 CDJ88891.1 - 7 6.8 6.6 1.9 8.6 1.7 2.5 2 0 0 2 2 2 0 Malate dehydrogenase enzyme PTEN_C2 PF10409.9 CDJ88892.1 - 3.8e-12 46.1 0.0 5.6e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein HIG_1_N PF04588.13 CDJ88894.1 - 2.6e-13 50.0 3.6 3.6e-13 49.5 3.6 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF1075 PF06388.11 CDJ88895.1 - 7.5e-06 26.0 0.0 1e-05 25.5 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1075) DUF1644 PF07800.12 CDJ88895.1 - 0.013 15.5 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) SecY PF00344.20 CDJ88895.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 SecY translocase Beta-lactamase PF00144.24 CDJ88896.1 - 5.1e-64 216.6 0.0 6e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 CDJ88896.1 - 0.043 13.4 0.1 0.96 9.0 0.0 2.4 3 0 0 3 3 3 0 Beta-lactamase enzyme family Beta-lactamase PF00144.24 CDJ88897.1 - 2.6e-51 174.8 0.0 3.3e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase F-box PF00646.33 CDJ88898.1 - 0.0081 16.0 0.3 0.0081 16.0 0.3 2.5 3 0 0 3 3 3 1 F-box domain Ig_3 PF13927.6 CDJ88899.1 - 7.8e-42 141.8 0.2 5.7e-15 55.7 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 CDJ88899.1 - 7.1e-36 122.1 0.0 2.5e-12 46.7 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 CDJ88899.1 - 1.8e-29 101.9 0.1 4.5e-10 39.7 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 CDJ88899.1 - 1.6e-28 98.7 0.6 1.5e-09 37.9 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 CDJ88899.1 - 1.9e-16 60.2 3.8 0.00071 19.7 0.0 5.2 3 3 1 4 4 4 3 Immunoglobulin V-set domain Ig_5 PF16681.5 CDJ88899.1 - 5.9e-07 29.8 1.8 0.061 13.7 0.0 4.0 3 1 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 CDJ88899.1 - 7.5e-07 29.1 0.5 0.048 13.7 0.1 3.0 2 1 0 2 2 2 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 CDJ88899.1 - 0.0053 17.1 2.9 0.19 12.1 0.0 3.6 4 1 0 4 4 4 1 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 CDJ88899.1 - 0.0075 16.3 0.1 2.8 8.1 0.0 3.0 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 CDJ88899.1 - 0.0092 15.5 0.0 5.5 6.6 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin domain Peptidase_S55 PF05580.12 CDJ88899.1 - 0.094 12.7 0.0 6.4 6.7 0.0 2.2 2 0 0 2 2 2 0 SpoIVB peptidase S55 Macoilin PF09726.9 CDJ88900.1 - 0.5 8.8 7.1 0.69 8.4 7.1 1.2 1 0 0 1 1 1 0 Macoilin family Pkinase_Tyr PF07714.17 CDJ88901.1 - 4.1e-64 216.3 0.1 7e-64 215.6 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ88901.1 - 2.5e-63 213.9 0.5 8e-63 212.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Haspin_kinase PF12330.8 CDJ88901.1 - 0.0021 17.1 0.0 0.013 14.5 0.0 2.0 1 1 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 CDJ88901.1 - 0.0081 15.5 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CDJ88901.1 - 0.0081 15.8 0.3 0.031 13.9 0.0 2.0 2 1 0 2 2 2 1 RIO1 family APH PF01636.23 CDJ88901.1 - 0.031 14.2 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Myc-LZ PF02344.15 CDJ88901.1 - 0.44 10.7 4.7 0.78 9.9 3.1 2.3 2 0 0 2 2 2 0 Myc leucine zipper domain OTU PF02338.19 CDJ88902.1 - 2.6e-29 102.3 0.1 1.1e-28 100.3 0.0 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease TAP_C PF03943.13 CDJ88902.1 - 0.0037 16.9 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 TAP C-terminal domain DUF4781 PF16013.5 CDJ88903.1 - 0.42 9.4 4.0 0.85 8.4 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Spem1 PF15670.5 CDJ88903.1 - 2.5 7.6 18.1 0.29 10.7 12.2 2.3 2 1 1 3 3 3 0 Spermatid maturation protein 1 eIF-3_zeta PF05091.12 CDJ88903.1 - 3.2 6.6 11.2 4.9 6.0 11.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4834 PF16118.5 CDJ88908.1 - 0.0075 17.2 0.9 0.021 15.8 0.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) V_ATPase_I PF01496.19 CDJ88908.1 - 0.013 13.5 0.6 0.029 12.3 0.5 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 CDJ88908.1 - 0.016 15.0 1.0 0.027 14.2 0.2 1.7 2 0 0 2 2 2 0 Connexin Zip PF02535.22 CDJ88908.1 - 0.19 10.9 0.8 0.31 10.2 0.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 CDJ88908.1 - 1 8.0 3.0 1.4 7.6 3.0 1.2 1 0 0 1 1 1 0 Presenilin RT_RNaseH_2 PF17919.1 CDJ88909.1 - 3.6e-30 104.0 0.0 7e-30 103.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ88909.1 - 4.1e-27 94.5 0.0 7e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ88909.1 - 2.4e-12 46.9 0.0 3.5e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PhoU PF01895.19 CDJ88910.1 - 0.024 15.1 1.7 0.024 15.1 1.7 3.4 1 1 1 2 2 2 0 PhoU domain FAD-SLDH PF12318.8 CDJ88910.1 - 0.098 12.7 0.6 0.25 11.4 0.2 1.9 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase DUF4407 PF14362.6 CDJ88910.1 - 0.16 11.3 9.7 0.23 10.8 9.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Herpes_UL25 PF01499.16 CDJ88910.1 - 0.43 9.0 9.1 0.077 11.5 5.1 1.6 2 0 0 2 2 2 0 Herpesvirus UL25 family PKcGMP_CC PF16808.5 CDJ88910.1 - 0.51 10.2 15.2 2.5 8.0 2.0 4.3 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase AAA_13 PF13166.6 CDJ88910.1 - 0.91 8.1 16.0 2.1 6.9 16.0 1.5 1 1 0 1 1 1 0 AAA domain CARM1 PF11531.8 CDJ88910.1 - 1.1 9.5 3.6 12 6.1 0.3 2.6 1 1 1 2 2 2 0 Coactivator-associated arginine methyltransferase 1 N terminal DivIC PF04977.15 CDJ88910.1 - 2.5 7.9 15.8 1 9.2 0.2 3.7 3 1 0 3 3 3 0 Septum formation initiator PNRC PF15365.6 CDJ88911.1 - 1e-06 28.3 0.8 1e-06 28.3 0.8 2.5 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif MCM_OB PF17207.3 CDJ88912.1 - 0.13 12.2 2.1 5.6 6.8 0.0 2.2 1 1 1 2 2 2 0 MCM OB domain ABC_membrane PF00664.23 CDJ88913.2 - 7.4e-42 143.9 12.6 1e-41 143.4 12.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ88913.2 - 8.7e-22 78.1 0.0 3.6e-21 76.1 0.0 2.0 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CDJ88913.2 - 2e-07 30.7 0.0 2.5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain TrkA_N PF02254.18 CDJ88913.2 - 0.055 13.7 0.0 0.28 11.4 0.0 2.2 1 1 1 2 2 2 0 TrkA-N domain SbcCD_C PF13558.6 CDJ88913.2 - 0.26 11.6 4.2 6.3 7.1 0.6 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit His_Phos_2 PF00328.22 CDJ88915.1 - 2.6e-09 36.9 0.0 3.6e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1647 PF07801.11 CDJ88916.1 - 2.7e-24 85.5 0.0 3.8e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) AGP PF06376.12 CDJ88916.1 - 0.36 10.7 0.3 0.36 10.7 0.3 1.8 2 0 0 2 2 2 0 Arabinogalactan peptide Pkinase PF00069.25 CDJ88917.1 - 3.4e-69 233.1 0.0 4.1e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ88917.1 - 8.6e-36 123.5 0.0 1.2e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ88917.1 - 0.0007 18.6 0.7 0.0011 18.0 0.7 1.3 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CDJ88917.1 - 0.0027 17.7 0.0 0.007 16.3 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CDJ88917.1 - 0.0053 16.1 0.0 0.054 12.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like YukC PF10140.9 CDJ88917.1 - 0.011 14.6 0.1 0.016 14.1 0.1 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC RIO1 PF01163.22 CDJ88917.1 - 0.027 14.1 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 CDJ88917.1 - 0.033 13.5 0.4 0.053 12.9 0.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CDJ88917.1 - 0.057 13.0 0.5 0.13 11.9 0.1 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 CDJ88917.1 - 0.24 10.1 1.2 1.4 7.6 0.2 1.9 1 1 1 2 2 2 0 Fungal protein kinase Pkinase PF00069.25 CDJ88918.1 - 3.4e-69 233.1 0.0 4.1e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ88918.1 - 8.6e-36 123.5 0.0 1.2e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ88918.1 - 0.0007 18.6 0.7 0.0011 18.0 0.7 1.3 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CDJ88918.1 - 0.0027 17.7 0.0 0.007 16.3 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CDJ88918.1 - 0.0053 16.1 0.0 0.054 12.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like YukC PF10140.9 CDJ88918.1 - 0.011 14.6 0.1 0.016 14.1 0.1 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC RIO1 PF01163.22 CDJ88918.1 - 0.027 14.1 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 CDJ88918.1 - 0.033 13.5 0.4 0.053 12.9 0.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CDJ88918.1 - 0.057 13.0 0.5 0.13 11.9 0.1 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 CDJ88918.1 - 0.24 10.1 1.2 1.4 7.6 0.2 1.9 1 1 1 2 2 2 0 Fungal protein kinase DUF148 PF02520.17 CDJ88919.1 - 0.001 19.2 1.1 0.001 19.2 1.1 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF148 BPS1 PF05633.11 CDJ88919.1 - 0.016 14.2 1.3 0.018 14.0 0.4 1.5 2 0 0 2 2 2 0 Protein BYPASS1-related Gp-FAR-1 PF05823.12 CDJ88919.1 - 0.037 14.4 2.4 0.74 10.2 1.0 2.5 2 2 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) GPAT_N PF14829.6 CDJ88919.1 - 0.099 12.6 0.3 0.89 9.6 0.0 2.4 3 0 0 3 3 3 0 Glycerol-3-phosphate acyltransferase N-terminal Mit_ribos_Mrp51 PF11709.8 CDJ88919.1 - 0.21 11.2 2.0 0.24 10.9 2.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit E1_dh PF00676.20 CDJ88921.1 - 7e-72 241.9 0.0 9.9e-72 241.4 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 CDJ88921.1 - 1.4e-66 223.5 0.0 2.1e-66 223.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 CDJ88921.1 - 4.4e-53 179.1 0.0 8.2e-53 178.2 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 CDJ88921.1 - 1.6e-18 66.0 7.9 3.9e-18 64.8 0.7 3.3 3 0 0 3 3 3 1 2-oxoglutarate dehydrogenase N-terminus R2K_2 PF18299.1 CDJ88921.1 - 0.017 15.0 0.0 0.05 13.5 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain, R2K clade family 2 RepB PF07506.11 CDJ88921.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 RepB plasmid partitioning protein E1_dh PF00676.20 CDJ88922.1 - 1.6e-71 240.8 0.0 2.3e-71 240.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 CDJ88922.1 - 6.4e-68 227.9 0.0 1e-67 227.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 CDJ88922.1 - 1.6e-52 177.2 0.0 3e-52 176.4 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 CDJ88922.1 - 8.5e-18 63.7 0.8 8.5e-18 63.7 0.8 3.2 3 0 0 3 3 3 1 2-oxoglutarate dehydrogenase N-terminus R2K_2 PF18299.1 CDJ88922.1 - 0.031 14.1 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain, R2K clade family 2 RepB PF07506.11 CDJ88922.1 - 0.16 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 RepB plasmid partitioning protein Frag1 PF10277.9 CDJ88923.1 - 1.8e-30 106.1 15.5 2.1e-30 105.9 15.5 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family SLATT_1 PF18181.1 CDJ88923.1 - 0.065 13.2 0.3 0.2 11.6 0.1 1.9 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 DUF4418 PF14387.6 CDJ88923.1 - 2.1 8.6 7.2 0.15 12.2 2.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) RNA_pol_Rpc34 PF05158.12 CDJ88924.1 - 1.7e-49 169.0 6.5 4.1e-48 164.5 6.5 2.3 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 CDJ88924.1 - 0.0025 17.9 0.1 0.0042 17.2 0.1 1.4 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC GntR PF00392.21 CDJ88924.1 - 0.093 12.4 0.0 0.26 10.9 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family TrmB PF01978.19 CDJ88924.1 - 0.096 12.6 0.2 0.38 10.7 0.1 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Collagen PF01391.18 CDJ88925.1 - 5.3e-21 74.2 64.5 1e-10 41.2 31.1 2.9 2 1 0 2 2 2 2 Collagen triple helix repeat (20 copies) SL4P PF17618.2 CDJ88926.1 - 7e-30 102.9 0.2 9.1e-30 102.6 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized Strongylid L4 protein Tom37 PF10568.9 CDJ88927.1 - 0.094 13.0 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein TLE_N PF03920.15 CDJ88928.1 - 0.01 15.9 0.6 0.021 14.9 0.1 1.8 2 0 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain BCAS3 PF12490.8 CDJ88928.1 - 0.24 10.9 0.7 0.36 10.3 0.7 1.3 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 Lipoprotein_20 PF13942.6 CDJ88929.1 - 0.0028 17.6 0.2 0.0062 16.5 0.0 1.6 2 0 0 2 2 2 1 YfhG lipoprotein acVLRF1 PF18859.1 CDJ88929.1 - 0.025 14.9 0.5 0.036 14.4 0.5 1.2 1 0 0 1 1 1 0 Actinobacteria/chloroflexi VLRF1 release factor DUF2461 PF09365.10 CDJ88929.1 - 0.039 13.9 0.6 0.077 12.9 0.3 1.6 1 1 0 1 1 1 0 Conserved hypothetical protein (DUF2461) Lipoprotein_20 PF13942.6 CDJ88930.1 - 0.0028 17.6 0.2 0.0062 16.5 0.0 1.6 2 0 0 2 2 2 1 YfhG lipoprotein acVLRF1 PF18859.1 CDJ88930.1 - 0.025 14.9 0.5 0.036 14.4 0.5 1.2 1 0 0 1 1 1 0 Actinobacteria/chloroflexi VLRF1 release factor DUF2461 PF09365.10 CDJ88930.1 - 0.039 13.9 0.6 0.077 12.9 0.3 1.6 1 1 0 1 1 1 0 Conserved hypothetical protein (DUF2461) DUF4440 PF14534.6 CDJ88931.1 - 0.013 15.9 0.0 0.02 15.3 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) C2 PF00168.30 CDJ88932.1 - 9.3e-58 192.9 2.1 1.6e-30 105.5 0.0 3.3 4 0 0 4 4 4 2 C2 domain CEP76-C2 PF15627.6 CDJ88932.1 - 0.0018 17.9 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 2 CEP76 C2 domain DUF4834 PF16118.5 CDJ88932.1 - 0.0019 19.1 1.2 0.0025 18.7 0.1 1.7 2 0 0 2 2 1 1 Domain of unknown function (DUF4834) RIC3 PF15361.6 CDJ88932.1 - 0.0043 17.4 1.1 0.0081 16.6 1.1 1.4 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 PMT_2 PF13231.6 CDJ88932.1 - 0.0072 16.6 0.2 0.012 15.9 0.2 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MAP17 PF15807.5 CDJ88932.1 - 0.031 14.5 0.2 0.061 13.5 0.2 1.5 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF1673 PF07895.11 CDJ88932.1 - 0.042 13.6 0.2 0.091 12.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF997 PF06196.12 CDJ88932.1 - 0.062 13.3 0.3 0.12 12.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF997) S-antigen PF05756.11 CDJ88932.1 - 0.064 13.6 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 S-antigen protein TMEM154 PF15102.6 CDJ88932.1 - 0.088 12.7 2.8 0.26 11.2 2.8 1.8 1 1 0 1 1 1 0 TMEM154 protein family PTEN_C2 PF10409.9 CDJ88932.1 - 0.11 12.3 2.2 12 5.7 0.1 3.1 2 1 1 3 3 3 0 C2 domain of PTEN tumour-suppressor protein DoxX_2 PF13564.6 CDJ88932.1 - 0.19 11.9 0.6 0.43 10.7 0.6 1.5 1 0 0 1 1 1 0 DoxX-like family FeoB_associated PF12669.7 CDJ88932.1 - 2.8 8.4 8.8 0.11 13.0 2.6 1.8 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein BAH PF01426.18 CDJ88933.1 - 1.6e-12 47.4 0.0 3.7e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 BAH domain GATA PF00320.27 CDJ88933.1 - 2.3e-08 33.5 1.4 5.4e-08 32.3 1.4 1.7 1 0 0 1 1 1 1 GATA zinc finger ELM2 PF01448.24 CDJ88933.1 - 7.3e-06 26.6 0.0 2.5e-05 24.9 0.0 2.0 1 0 0 1 1 1 1 ELM2 domain RabGAP-TBC PF00566.18 CDJ88934.1 - 7.9e-47 159.7 0.0 1.1e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF726 PF05277.12 CDJ88935.1 - 1.1e-130 435.6 5.1 1.6e-130 435.0 5.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) LCAT PF02450.15 CDJ88935.1 - 0.043 13.0 0.0 0.095 11.8 0.0 1.5 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 CDJ88935.1 - 0.14 12.7 1.6 2 8.9 0.2 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF4746 PF15928.5 CDJ88936.1 - 6 6.2 17.2 7.2 5.9 17.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RVT_1 PF00078.27 CDJ88937.1 - 8.1e-09 35.3 0.1 1.7e-08 34.2 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SAPIS-gp6 PF16722.5 CDJ88938.1 - 0.15 12.5 3.1 11 6.5 0.1 2.3 1 1 1 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus PhyH PF05721.13 CDJ88940.1 - 6.2e-37 127.9 0.2 8.1e-37 127.5 0.2 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Neur_chan_LBD PF02931.23 CDJ88941.1 - 3.9e-55 186.6 5.4 4.6e-55 186.4 5.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ88941.1 - 1.8e-07 31.4 2.0 2.6e-07 30.9 2.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region RT_RNaseH PF17917.1 CDJ88942.1 - 1.5e-32 112.0 0.0 2.6e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ88942.1 - 2.8e-24 85.0 0.0 6.2e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ88942.1 - 2.4e-16 59.6 0.0 4.1e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDJ88942.1 - 4.8e-07 30.0 0.2 0.00087 19.5 0.0 3.5 3 1 1 4 4 4 2 Integrase core domain rve_3 PF13683.6 CDJ88942.1 - 0.0051 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain MDH PF02315.16 CDJ88942.1 - 0.16 12.1 1.0 0.28 11.3 0.2 1.8 2 0 0 2 2 2 0 Methanol dehydrogenase beta subunit Phosphodiest PF01663.22 CDJ88943.1 - 4.6e-42 144.9 3.1 5.7e-42 144.6 3.1 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CDJ88943.1 - 0.15 11.5 2.2 0.92 8.8 2.2 2.3 1 1 0 1 1 1 0 Sulfatase Pkinase_Tyr PF07714.17 CDJ88944.1 - 9.7e-77 257.7 0.0 1.3e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ88944.1 - 4.1e-47 160.8 0.0 5.8e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain F5_F8_type_C PF00754.25 CDJ88944.1 - 2.5e-20 72.9 0.0 2.9e-18 66.2 0.0 2.2 2 0 0 2 2 2 1 F5/8 type C domain Haspin_kinase PF12330.8 CDJ88944.1 - 0.00031 19.8 0.0 0.00059 18.9 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Reo_sigmaC_M PF17750.1 CDJ88944.1 - 0.016 15.0 0.3 0.043 13.7 0.3 1.7 1 0 0 1 1 1 0 Reovirus sigma C capsid protein triple beta spiral Kinase-like PF14531.6 CDJ88944.1 - 0.016 14.5 0.0 0.055 12.8 0.0 1.7 1 1 0 1 1 1 0 Kinase-like ELF PF03317.13 CDJ88944.1 - 0.059 13.4 0.0 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 ELF protein RIO1 PF01163.22 CDJ88944.1 - 0.079 12.6 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family SH3_19 PF18597.1 CDJ88944.1 - 0.1 12.4 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 Myosin X N-terminal SH3 domain LBP_BPI_CETP_C PF02886.17 CDJ88945.1 - 5.9e-38 130.7 1.2 9e-38 130.0 1.2 1.2 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 CDJ88945.1 - 3.9e-08 33.1 1.9 2.9e-07 30.3 0.1 2.4 2 1 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain JHBP PF06585.11 CDJ88945.1 - 0.11 11.7 0.0 6.6 5.8 0.0 2.2 2 0 0 2 2 2 0 Haemolymph juvenile hormone binding protein (JHBP) Neur_chan_memb PF02932.16 CDJ88946.1 - 2.5e-07 31.0 0.5 2.9e-07 30.8 0.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region HlyE PF06109.13 CDJ88946.1 - 0.04 13.2 0.0 0.043 13.1 0.0 1.1 1 0 0 1 1 1 0 Haemolysin E (HlyE) Exo_endo_phos PF03372.23 CDJ88947.1 - 1.7e-11 44.1 0.0 3e-11 43.3 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Biotin_lipoyl PF00364.22 CDJ88947.1 - 0.0013 18.5 0.8 0.11 12.3 0.7 2.9 3 0 0 3 3 3 1 Biotin-requiring enzyme Exo_endo_phos_2 PF14529.6 CDJ88947.1 - 0.02 14.8 0.3 3.4 7.5 0.0 2.7 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase SHIPPO-rpt PF07004.12 CDJ88948.1 - 0.54 11.3 4.8 17 6.5 1.2 2.6 2 0 0 2 2 2 0 Sperm-tail PG-rich repeat Septin PF00735.18 CDJ88949.1 - 5.2e-97 324.5 0.1 8.5e-97 323.8 0.1 1.3 1 0 0 1 1 1 1 Septin AAA_22 PF13401.6 CDJ88949.1 - 0.00081 19.7 0.0 0.0036 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CDJ88949.1 - 0.0015 18.6 0.0 0.0033 17.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ88949.1 - 0.0023 17.5 0.1 1.5 8.3 0.1 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CDJ88949.1 - 0.0027 18.1 1.7 0.005 17.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 CDJ88949.1 - 0.0034 16.9 0.0 0.0076 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 CDJ88949.1 - 0.012 15.5 0.1 0.22 11.4 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase Roc PF08477.13 CDJ88949.1 - 0.017 15.3 0.0 0.04 14.1 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Microtub_bd PF16796.5 CDJ88949.1 - 0.041 13.8 0.0 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 Microtubule binding PduV-EutP PF10662.9 CDJ88949.1 - 0.15 11.8 0.1 0.6 9.9 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 CDJ88949.1 - 0.17 12.4 0.8 0.47 11.0 0.1 2.2 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 CDJ88949.1 - 2.9 8.4 13.2 2.2 8.8 0.1 2.6 2 1 0 2 2 2 0 AAA domain MARVEL PF01284.23 CDJ88950.1 - 5.1e-13 49.3 13.1 6.4e-13 49.0 13.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain TTR-52 PF01060.23 CDJ88951.1 - 5.1e-14 52.7 0.1 8.6e-14 52.0 0.1 1.3 1 0 0 1 1 1 1 Transthyretin-like family CAP PF00188.26 CDJ88952.1 - 1.6e-37 129.2 9.0 1.3e-20 74.5 1.6 2.2 2 0 0 2 2 2 2 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ88952.1 - 1.6e-07 31.6 1.9 0.021 15.1 0.4 3.2 2 1 0 2 2 2 2 Ancylostoma-associated secreted protein related EB PF01683.18 CDJ88952.1 - 0.016 15.5 17.6 0.46 10.8 3.8 2.8 2 0 0 2 2 2 0 EB module WAP PF00095.21 CDJ88952.1 - 8 6.9 10.8 0.72 10.3 3.2 2.8 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' CAP PF00188.26 CDJ88954.1 - 3.6e-40 137.7 10.9 1.5e-20 74.3 1.5 2.5 3 0 0 3 3 3 2 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ88954.1 - 0.0015 18.8 8.3 0.071 13.4 1.4 3.4 3 2 0 3 3 3 2 Ancylostoma-associated secreted protein related WAP PF00095.21 CDJ88954.1 - 1.4 9.4 8.0 0.5 10.8 1.5 3.1 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' ASC PF00858.24 CDJ88955.1 - 0.027 13.5 1.3 0.045 12.7 1.3 1.3 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel Claudin_3 PF06653.11 CDJ88956.1 - 4.6e-17 62.4 13.6 5.9e-17 62.1 13.6 1.0 1 0 0 1 1 1 1 Tight junction protein, Claudin-like DUF1230 PF06799.11 CDJ88956.1 - 7.7 6.6 6.4 11 6.1 0.3 2.8 3 0 0 3 3 3 0 Conserved in the green lineage and diatoms 27 DUF4190 PF13828.6 CDJ88956.1 - 8.2 6.3 9.8 2.3 8.1 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) Claudin_3 PF06653.11 CDJ88957.1 - 3.5e-10 40.1 4.8 6.8e-10 39.1 4.8 1.4 1 1 0 1 1 1 1 Tight junction protein, Claudin-like Clc-like PF07062.12 CDJ88957.1 - 0.014 14.9 3.9 0.019 14.4 3.9 1.1 1 0 0 1 1 1 0 Clc-like Prenyltrans PF00432.21 CDJ88957.1 - 0.041 13.6 0.1 0.098 12.4 0.1 1.5 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat DUF2231 PF09990.9 CDJ88957.1 - 0.1 13.0 3.0 5.8 7.4 0.2 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) SdpI PF13630.6 CDJ88957.1 - 0.43 10.7 4.5 0.58 10.3 0.3 2.2 2 0 0 2 2 2 0 SdpI/YhfL protein family ShK PF01549.24 CDJ88958.1 - 2e-20 73.0 48.2 4.2e-07 30.4 6.7 5.4 6 0 0 6 6 6 4 ShK domain-like Zn_ribbon_17 PF17120.5 CDJ88958.1 - 8.6 6.1 17.1 2.9 7.6 10.5 3.2 2 1 1 3 3 3 0 Zinc-ribbon, C4HC2 type ShK PF01549.24 CDJ88961.1 - 1.4e-24 86.4 55.8 3.1e-09 37.2 10.1 4.9 6 0 0 6 6 6 4 ShK domain-like ShK PF01549.24 CDJ88964.1 - 7e-28 96.9 58.5 3.4e-12 46.7 11.1 5.0 5 1 0 5 5 5 4 ShK domain-like TTR-52 PF01060.23 CDJ88965.1 - 3.3e-06 27.7 0.0 5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Transthyretin-like family TTR-52 PF01060.23 CDJ88966.1 - 0.00017 22.2 0.0 0.00022 21.9 0.0 1.2 1 0 0 1 1 1 1 Transthyretin-like family ABC_membrane_2 PF06472.15 CDJ88967.1 - 2e-52 178.3 7.2 2.8e-52 177.8 7.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CDJ88967.1 - 2.5e-18 66.9 0.0 4.1e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 CDJ88967.1 - 0.00065 20.1 0.0 0.0013 19.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.26 CDJ88967.1 - 0.002 17.9 0.0 0.7 9.6 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain RsgA_GTPase PF03193.16 CDJ88967.1 - 0.0022 17.9 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 CDJ88967.1 - 0.0025 17.5 0.0 0.0087 15.8 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 CDJ88967.1 - 0.022 14.5 0.0 0.059 13.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CDJ88967.1 - 0.029 14.6 0.0 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CDJ88967.1 - 0.12 12.2 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 CDJ88967.1 - 0.19 12.3 0.0 0.35 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RVT_1 PF00078.27 CDJ88969.1 - 1.5e-07 31.1 0.0 2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Reprolysin_2 PF13574.6 CDJ88971.1 - 1.5e-32 113.1 0.0 2.3e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CDJ88971.1 - 2e-27 96.7 0.0 2e-27 96.7 0.0 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12 Disintegrin PF00200.23 CDJ88971.1 - 2.1e-12 47.6 21.8 2.1e-12 47.6 21.8 3.3 2 1 0 2 2 2 1 Disintegrin Reprolysin_3 PF13582.6 CDJ88971.1 - 3.5e-11 43.7 0.0 7.6e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM17_MPD PF16698.5 CDJ88971.1 - 2.9e-10 40.4 13.9 2.9e-10 40.4 13.9 3.7 2 1 0 2 2 2 1 Membrane-proximal domain, switch, for ADAM17 Reprolysin PF01421.19 CDJ88971.1 - 3.7e-06 27.0 0.1 0.055 13.4 0.0 2.4 2 0 0 2 2 2 2 Reprolysin (M12B) family zinc metalloprotease Reprolysin_4 PF13583.6 CDJ88971.1 - 0.00016 21.4 2.9 0.0016 18.2 0.1 2.5 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 CDJ88971.1 - 0.00049 20.3 0.0 0.0012 19.1 0.0 1.6 2 0 0 2 2 2 1 Reprolysin family propeptide MOSC PF03473.17 CDJ88973.1 - 1.1e-21 77.3 0.0 2e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.19 CDJ88973.1 - 3.4e-20 72.3 0.0 5.5e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 CDJ88973.1 - 2.9e-17 62.7 0.0 7.2e-17 61.4 0.0 1.7 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain RT_RNaseH PF17917.1 CDJ88975.1 - 0.03 14.6 1.3 0.08 13.2 0.3 2.0 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Astacin PF01400.24 CDJ88977.1 - 2.1e-34 118.8 0.0 3.2e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 CDJ88977.1 - 0.0019 18.1 0.4 0.013 15.3 0.1 1.9 1 1 0 2 2 2 1 Matrixin RasGEF PF00617.19 CDJ88978.1 - 1.1e-42 146.2 1.6 3.1e-42 144.8 0.0 2.2 2 1 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 CDJ88978.1 - 7.8e-11 42.2 0.1 2.5e-10 40.5 0.1 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif Glycos_transf_2 PF00535.26 CDJ88979.1 - 2e-25 89.6 0.0 3.3e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CDJ88979.1 - 4.4e-17 62.5 1.9 7.2e-17 61.8 1.9 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 CDJ88979.1 - 4.4e-07 30.5 0.1 2e-05 25.2 0.0 2.4 1 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Glyco_transf_7C PF02709.14 CDJ88979.1 - 8.9e-06 25.3 0.2 2.1e-05 24.1 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CDJ88979.1 - 4e-05 23.2 0.0 7.9e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 ATP_synth_reg PF14960.6 CDJ88979.1 - 0.18 11.3 0.1 0.38 10.3 0.1 1.6 1 0 0 1 1 1 0 ATP synthase regulation HTH_38 PF13936.6 CDJ88980.1 - 0.046 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Claudin_3 PF06653.11 CDJ88981.1 - 7e-10 39.1 2.4 7.8e-10 38.9 2.4 1.0 1 0 0 1 1 1 1 Tight junction protein, Claudin-like Claudin_2 PF13903.6 CDJ88981.1 - 0.0068 16.2 2.8 0.0079 16.0 2.8 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 CDJ88981.1 - 0.0075 16.2 1.0 0.0089 15.9 1.0 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Amastin PF07344.11 CDJ88981.1 - 0.011 15.6 6.4 0.013 15.4 6.4 1.1 1 0 0 1 1 1 0 Amastin surface glycoprotein DuoxA PF10204.9 CDJ88981.1 - 0.045 12.8 3.2 0.045 12.8 3.2 1.0 1 0 0 1 1 1 0 Dual oxidase maturation factor Phage_holin_3_6 PF07332.11 CDJ88981.1 - 0.045 13.8 8.3 0.054 13.5 8.3 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III PsiE PF06146.12 CDJ88981.1 - 0.058 13.8 3.7 0.15 12.5 0.2 2.1 2 0 0 2 2 2 0 Phosphate-starvation-inducible E SUR7 PF06687.12 CDJ88981.1 - 0.12 12.0 3.7 0.15 11.7 3.7 1.2 1 0 0 1 1 1 0 SUR7/PalI family MHYT PF03707.16 CDJ88981.1 - 0.35 11.1 6.1 0.54 10.5 0.6 2.1 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat COesterase PF00135.28 CDJ88982.1 - 7.7e-143 477.1 0.0 9.3e-143 476.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDJ88982.1 - 7.3e-13 48.9 0.1 2.5e-12 47.1 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CDJ88982.1 - 0.0016 18.0 0.0 0.0033 16.9 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CDJ88982.1 - 0.028 15.0 0.6 0.048 14.3 0.6 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 CDJ88982.1 - 0.11 12.2 0.0 3.1 7.4 0.0 2.1 2 0 0 2 2 2 0 Putative esterase Amidohydro_1 PF01979.20 CDJ88983.1 - 3.5e-46 158.1 0.0 3.9e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family AP_endonuc_2 PF01261.24 CDJ88983.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Amidohydro_3 PF07969.11 CDJ88983.1 - 0.034 13.6 0.0 0.32 10.4 0.0 2.0 2 1 0 2 2 2 0 Amidohydrolase family DUF2935 PF11155.8 CDJ88983.1 - 0.065 13.6 0.4 0.11 12.8 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) DUF2478 PF10649.9 CDJ88983.1 - 0.16 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) EGF_2 PF07974.13 CDJ88986.1 - 0.074 13.4 12.0 1.4 9.4 5.1 2.7 1 1 1 2 2 2 0 EGF-like domain EGF_Tenascin PF18720.1 CDJ88986.1 - 0.16 12.0 0.6 0.16 12.0 0.6 2.4 2 1 0 2 2 2 0 Tenascin EGF domain Laminin_EGF PF00053.24 CDJ88986.1 - 0.26 11.5 12.0 1.6 8.9 9.9 2.3 1 1 1 2 2 2 0 Laminin EGF domain HTH_26 PF13443.6 CDJ88987.1 - 0.00029 21.2 0.1 0.00071 20.0 0.1 1.6 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain Ribosomal_L19e PF01280.20 CDJ88987.1 - 0.0076 16.3 2.2 1.4 8.9 0.3 2.4 2 0 0 2 2 2 2 Ribosomal protein L19e HTH_IclR PF09339.10 CDJ88987.1 - 0.0085 15.9 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 CDJ88987.1 - 0.016 15.1 0.1 0.034 14.0 0.1 1.5 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 CDJ88987.1 - 0.04 13.5 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_ISL3 PF13542.6 CDJ88987.1 - 0.068 12.6 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 CENP-B_N PF04218.13 CDJ88987.1 - 0.073 12.7 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_3 PF01381.22 CDJ88987.1 - 0.096 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix DUF2095 PF09868.9 CDJ88987.1 - 0.2 11.6 1.6 16 5.5 0.1 2.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2095) RVT_1 PF00078.27 CDJ88988.1 - 5.6e-06 26.0 0.0 8.7e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) XhlA PF10779.9 CDJ88989.1 - 0.029 14.6 0.0 0.091 13.0 0.0 1.8 1 0 0 1 1 1 0 Haemolysin XhlA Peptidase_S10 PF00450.22 CDJ88990.1 - 1.4e-23 84.0 0.0 1.6e-23 83.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 CDJ88992.1 - 3.3e-118 395.7 5.9 3.8e-118 395.5 5.9 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase FXR_C1 PF16096.5 CDJ88992.1 - 0.088 13.0 0.2 0.22 11.7 0.2 1.6 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 Branch PF02485.21 CDJ88993.1 - 1.2e-12 47.9 0.0 1.7e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme HLH PF00010.26 CDJ88995.1 - 1.5e-12 47.2 0.2 3.6e-12 46.1 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HrpJ PF07201.11 CDJ88995.1 - 0.039 14.3 2.3 0.052 13.9 0.5 1.9 2 0 0 2 2 2 0 HrpJ-like domain TRAP-gamma PF07074.12 CDJ88996.1 - 6.2e-70 234.2 7.1 7.2e-70 234.0 7.1 1.0 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF3270 PF11674.8 CDJ88996.1 - 0.0014 18.8 1.6 0.0014 18.8 1.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3270) Phage_holin_7_1 PF16081.5 CDJ88996.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF2207 PF09972.9 CDJ88996.1 - 2.4 6.8 7.2 0.36 9.6 2.3 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Sec61_beta PF03911.16 CDJ88997.1 - 6.1e-20 71.0 0.0 7.2e-20 70.7 0.0 1.1 1 0 0 1 1 1 1 Sec61beta family RVT_1 PF00078.27 CDJ88998.1 - 3.5e-26 92.1 0.0 5.7e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FlgM PF04316.13 CDJ88999.1 - 0.49 10.8 0.1 0.49 10.8 0.1 2.4 3 0 0 3 3 3 0 Anti-sigma-28 factor, FlgM GTP_EFTU PF00009.27 CDJ89000.1 - 4.2e-54 183.0 0.0 7.5e-54 182.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 CDJ89000.1 - 2.8e-30 104.6 1.3 5.4e-30 103.7 1.3 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 CDJ89000.1 - 2.9e-18 65.7 0.0 6.6e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CDJ89000.1 - 3.9e-11 43.2 0.1 8.1e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDJ89000.1 - 1.4e-06 28.3 0.0 2.9e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 CDJ89000.1 - 4.9e-05 23.0 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 Ras family RF3_C PF16658.5 CDJ89000.1 - 0.00039 20.2 0.0 0.0009 19.1 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain RsgA_GTPase PF03193.16 CDJ89000.1 - 0.00083 19.3 0.1 0.011 15.6 0.1 2.3 1 1 1 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 CDJ89000.1 - 0.0096 15.9 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 CDJ89000.1 - 0.015 14.8 0.1 0.071 12.6 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B EFG_II PF14492.6 CDJ89000.1 - 0.15 12.1 0.0 1.3 9.2 0.0 2.4 1 1 0 1 1 1 0 Elongation Factor G, domain II SET PF00856.28 CDJ89001.1 - 3.1e-19 70.0 1.5 1.3e-18 67.9 0.1 2.9 3 0 0 3 3 3 1 SET domain RRM_1 PF00076.22 CDJ89001.1 - 1.7e-05 24.5 0.0 3.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ89001.1 - 0.022 14.6 0.0 0.085 12.7 0.0 1.9 2 0 0 2 2 2 0 Occluded RNA-recognition motif FeoB_Cyto PF17910.1 CDJ89001.1 - 2.1 8.9 5.7 0.46 11.1 0.1 2.6 2 1 1 3 3 3 0 FeoB cytosolic helical domain Cob_adeno_trans PF01923.18 CDJ89002.1 - 3.7e-49 167.0 0.0 4.5e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Cobalamin adenosyltransferase ThiF PF00899.21 CDJ89003.1 - 4.8e-22 78.5 0.0 1e-21 77.4 0.0 1.5 1 1 0 1 1 1 1 ThiF family GST_C_4 PF14834.6 CDJ89003.1 - 0.11 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Cas_VVA1548 PF09652.10 CDJ89003.1 - 0.12 12.6 0.0 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 Putative CRISPR-associated protein (Cas_VVA1548) PIF1 PF05970.14 CDJ89004.1 - 6.7e-07 28.8 0.0 8.5e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase T2SSE PF00437.20 CDJ89004.1 - 0.044 12.8 0.0 0.05 12.7 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.22 CDJ89004.1 - 0.048 12.8 0.0 0.084 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 CDJ89004.1 - 0.049 14.0 0.0 0.093 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DNA_pol_E_B PF04042.16 CDJ89005.1 - 3.5e-31 108.2 0.8 3.5e-31 108.2 0.8 1.7 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B RRM_1 PF00076.22 CDJ89006.1 - 1.5e-06 27.9 0.0 2.6e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RVT_1 PF00078.27 CDJ89008.1 - 0.00016 21.2 0.1 0.00034 20.2 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PD-C2-AF1 PF09310.10 CDJ89008.1 - 0.069 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 ERp29 PF07749.12 CDJ89008.1 - 0.076 13.9 2.1 2.1 9.3 0.7 2.5 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain Troponin PF00992.20 CDJ89010.1 - 3.8e-44 150.2 13.7 3.8e-44 150.2 13.7 2.1 2 0 0 2 2 2 1 Troponin Glyco_hydro_31 PF01055.26 CDJ89010.1 - 0.23 10.6 0.5 0.32 10.1 0.5 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 RTC4 PF14474.6 CDJ89010.1 - 0.91 9.7 4.3 0.22 11.7 0.8 1.7 2 0 0 2 2 2 0 RTC4-like domain Homeodomain PF00046.29 CDJ89011.1 - 3.1e-20 71.8 5.6 5.2e-20 71.0 5.6 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ89011.1 - 0.058 13.3 0.3 0.058 13.3 0.3 2.2 2 0 0 2 2 2 0 Homeobox KN domain DUF148 PF02520.17 CDJ89012.1 - 1.9e-23 82.6 5.0 2.2e-23 82.4 5.0 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF148 MAP65_ASE1 PF03999.12 CDJ89012.1 - 0.0033 16.2 1.2 0.0043 15.8 1.2 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) RmuC PF02646.16 CDJ89012.1 - 0.01 15.0 2.1 0.013 14.6 2.1 1.1 1 0 0 1 1 1 0 RmuC family SHE3 PF17078.5 CDJ89012.1 - 0.011 15.4 1.4 0.015 15.0 1.4 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 ArsA_ATPase PF02374.15 CDJ89012.1 - 0.018 14.3 2.1 0.023 13.9 2.1 1.1 1 0 0 1 1 1 0 Anion-transporting ATPase DUF241 PF03087.14 CDJ89012.1 - 0.028 14.3 0.4 0.035 14.0 0.4 1.1 1 0 0 1 1 1 0 Arabidopsis protein of unknown function DUF4107 PF13389.6 CDJ89012.1 - 0.036 14.2 0.6 0.053 13.7 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) YkyA PF10368.9 CDJ89012.1 - 0.036 13.7 4.2 0.059 13.0 4.2 1.3 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein Alpha-E PF04168.12 CDJ89012.1 - 0.04 13.7 0.0 0.049 13.4 0.0 1.1 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. Dor1 PF04124.12 CDJ89012.1 - 0.051 12.2 0.5 0.064 11.9 0.5 1.1 1 0 0 1 1 1 0 Dor1-like family Baculo_PEP_C PF04513.12 CDJ89012.1 - 0.061 13.4 0.0 0.08 13.0 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus MIS13 PF08202.11 CDJ89012.1 - 0.067 12.5 1.4 0.081 12.2 1.4 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family DUF1664 PF07889.12 CDJ89012.1 - 0.12 12.4 1.8 0.16 12.0 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) BshC PF10079.9 CDJ89012.1 - 0.12 11.1 3.3 0.14 10.9 3.3 1.0 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC DUF948 PF06103.11 CDJ89012.1 - 0.12 12.6 1.3 0.18 12.0 1.0 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Rav1p_C PF12234.8 CDJ89012.1 - 0.13 10.6 3.0 0.16 10.3 3.0 1.0 1 0 0 1 1 1 0 RAVE protein 1 C terminal TolA_bind_tri PF16331.5 CDJ89012.1 - 0.24 11.5 4.7 0.18 11.9 2.6 1.8 1 1 1 2 2 2 0 TolA binding protein trimerisation Fib_alpha PF08702.10 CDJ89012.1 - 0.27 11.4 1.9 0.37 11.0 1.9 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1043 PF06295.12 CDJ89012.1 - 1.1 9.3 7.7 11 6.0 7.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) DUF148 PF02520.17 CDJ89013.1 - 1e-23 83.5 5.1 1.4e-23 83.1 5.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF148 MAP65_ASE1 PF03999.12 CDJ89013.1 - 0.011 14.5 0.4 0.013 14.2 0.4 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) RmuC PF02646.16 CDJ89013.1 - 0.012 14.7 0.8 0.019 14.1 0.8 1.3 1 0 0 1 1 1 0 RmuC family Dor1 PF04124.12 CDJ89013.1 - 0.057 12.1 0.8 0.075 11.7 0.8 1.1 1 0 0 1 1 1 0 Dor1-like family Invas_SpaK PF03519.14 CDJ89013.1 - 0.059 13.4 0.1 0.13 12.4 0.1 1.6 1 1 0 1 1 1 0 Invasion protein B family Alpha-E PF04168.12 CDJ89013.1 - 0.077 12.8 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. FliJ PF02050.16 CDJ89013.1 - 0.25 11.6 5.3 1.2 9.4 0.6 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein YkyA PF10368.9 CDJ89013.1 - 0.28 10.8 4.3 0.95 9.1 4.5 1.6 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF1043 PF06295.12 CDJ89013.1 - 4.7 7.2 8.7 6.1 6.9 5.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) DUF2369 PF10179.9 CDJ89015.1 - 3e-14 53.2 0.2 4.2e-12 46.3 0.1 2.4 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2369) fn3 PF00041.21 CDJ89015.1 - 0.0069 16.7 0.0 23 5.4 0.0 3.9 3 1 0 3 3 3 2 Fibronectin type III domain HLH PF00010.26 CDJ89016.1 - 1.5e-17 63.2 1.1 2.9e-17 62.4 1.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pex14_N PF04695.13 CDJ89016.1 - 0.82 10.3 6.8 1.2 9.8 6.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C4H2 PF10146.9 CDJ89017.1 - 1.8e-48 165.6 14.3 2.3e-48 165.3 14.3 1.1 1 0 0 1 1 1 1 Zinc finger-containing protein zf-C3HC4_3 PF13920.6 CDJ89017.1 - 0.0081 16.0 4.3 0.014 15.3 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 CDJ89017.1 - 0.028 14.4 1.6 0.051 13.6 1.6 1.4 1 0 0 1 1 1 0 Double zinc ribbon Prok-RING_4 PF14447.6 CDJ89017.1 - 0.052 13.4 4.0 0.097 12.5 4.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CDJ89017.1 - 0.072 12.9 3.1 0.14 12.0 3.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 CDJ89017.1 - 0.21 11.5 4.7 0.38 10.6 4.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FliD_C PF07195.12 CDJ89017.1 - 0.25 10.7 3.1 0.32 10.4 3.1 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus FapA PF03961.13 CDJ89017.1 - 1.1 7.7 5.3 1.5 7.4 5.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Baculo_IE-1 PF05290.11 CDJ89017.1 - 1.2 9.1 5.6 2.2 8.2 1.5 2.2 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) UPF0242 PF06785.11 CDJ89017.1 - 2 8.5 12.1 2.8 8.0 12.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus zf-C4H2 PF10146.9 CDJ89018.1 - 2e-37 129.6 22.8 4.6e-37 128.4 22.8 1.5 1 1 0 1 1 1 1 Zinc finger-containing protein DUF1635 PF07795.11 CDJ89018.1 - 1.5e-05 25.0 3.4 2e-05 24.6 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) LUC7 PF03194.15 CDJ89018.1 - 9.2e-05 22.2 1.5 0.00013 21.8 1.5 1.1 1 0 0 1 1 1 1 LUC7 N_terminus DHR10 PF18595.1 CDJ89018.1 - 0.0019 18.2 9.8 0.003 17.6 9.8 1.2 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain OmpH PF03938.14 CDJ89018.1 - 0.0031 17.8 3.0 0.0048 17.2 3.0 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DZR PF12773.7 CDJ89018.1 - 0.0038 17.2 1.4 0.0038 17.2 1.4 1.8 2 0 0 2 2 2 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 CDJ89018.1 - 0.0041 16.8 2.3 0.0083 15.8 2.3 1.5 1 0 0 1 1 1 1 zinc-ribbon domain TPR_MLP1_2 PF07926.12 CDJ89018.1 - 0.005 16.9 5.9 0.0076 16.3 5.9 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 CDJ89018.1 - 0.0053 16.3 5.1 0.0068 15.9 5.1 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 zf-C3HC4_3 PF13920.6 CDJ89018.1 - 0.0059 16.4 3.5 0.0059 16.4 3.5 1.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SCP-1 PF05483.12 CDJ89018.1 - 0.0065 14.5 4.1 0.0078 14.3 4.1 1.1 1 0 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) zf-ribbon_3 PF13248.6 CDJ89018.1 - 0.0077 15.6 2.8 0.016 14.6 2.8 1.5 1 0 0 1 1 1 1 zinc-ribbon domain FliT PF05400.13 CDJ89018.1 - 0.0082 16.9 11.1 0.018 15.8 11.1 1.6 1 0 0 1 1 1 1 Flagellar protein FliT Tup_N PF08581.10 CDJ89018.1 - 0.011 16.1 7.1 0.018 15.3 7.1 1.3 1 0 0 1 1 1 0 Tup N-terminal DUF3584 PF12128.8 CDJ89018.1 - 0.014 12.9 3.8 0.017 12.7 3.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF724 PF05266.14 CDJ89018.1 - 0.018 14.9 3.3 0.024 14.5 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Laminin_II PF06009.12 CDJ89018.1 - 0.018 15.0 2.4 0.028 14.4 2.4 1.3 1 0 0 1 1 1 0 Laminin Domain II zf_C2HC_14 PF18574.1 CDJ89018.1 - 0.019 14.7 1.1 0.019 14.7 1.1 2.4 3 0 0 3 3 2 0 C2HC Zing finger domain FapA PF03961.13 CDJ89018.1 - 0.034 12.8 1.8 0.042 12.5 1.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A EPSP_synthase PF00275.20 CDJ89018.1 - 0.068 11.8 0.6 0.092 11.4 0.6 1.1 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Syntaxin_2 PF14523.6 CDJ89018.1 - 0.084 13.2 5.3 0.13 12.7 3.0 2.0 1 1 1 2 2 2 0 Syntaxin-like protein HAUS-augmin3 PF14932.6 CDJ89018.1 - 0.086 12.4 4.7 0.11 12.0 4.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 PI3K_P85_iSH2 PF16454.5 CDJ89018.1 - 0.23 11.1 8.9 0.52 9.9 8.2 1.7 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain V_ATPase_I PF01496.19 CDJ89018.1 - 0.23 9.3 1.3 0.27 9.1 1.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 CDJ89018.1 - 0.23 10.7 2.0 0.3 10.3 2.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF1515 PF07439.11 CDJ89018.1 - 0.24 11.4 4.4 0.42 10.7 3.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) Rho_Binding PF08912.11 CDJ89018.1 - 0.27 12.1 7.9 2.5 9.0 7.4 2.6 1 1 2 3 3 3 0 Rho Binding GrpE PF01025.19 CDJ89018.1 - 0.39 10.3 5.0 0.58 9.8 5.0 1.3 1 0 0 1 1 1 0 GrpE Prefoldin PF02996.17 CDJ89018.1 - 0.58 10.1 5.1 0.79 9.7 3.3 1.9 1 1 0 1 1 1 0 Prefoldin subunit DUF1664 PF07889.12 CDJ89018.1 - 1.2 9.2 3.3 1.7 8.7 1.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CCDC-167 PF15188.6 CDJ89018.1 - 1.2 9.5 8.8 1.8 9.0 7.9 1.7 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 zf-RING_2 PF13639.6 CDJ89018.1 - 2.6 8.5 7.2 0.6 10.5 1.9 2.1 2 0 0 2 2 2 0 Ring finger domain Baculo_IE-1 PF05290.11 CDJ89018.1 - 3.6 7.5 6.7 0.37 10.7 0.9 2.1 2 1 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-Mss51 PF13824.6 CDJ89018.1 - 5.7 7.1 7.9 5.9 7.1 0.9 3.2 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 YhfH PF14149.6 CDJ89018.1 - 7.3 6.7 9.3 6 6.9 2.9 2.5 2 0 0 2 2 2 0 YhfH-like protein DUF4140 PF13600.6 CDJ89018.1 - 9.5 6.7 8.4 85 3.7 8.4 2.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Collagen PF01391.18 CDJ89019.1 - 2.4e-19 68.8 100.2 3.4e-07 29.9 38.6 4.2 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ89019.1 - 0.002 18.1 0.0 0.0026 17.8 0.0 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain CENP-Q PF13094.6 CDJ89019.1 - 0.071 13.3 0.0 0.096 12.9 0.0 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Pkinase PF00069.25 CDJ89020.1 - 6e-19 68.4 0.0 7.3e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ89020.1 - 0.0054 16.0 0.0 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RVT_1 PF00078.27 CDJ89021.1 - 0.0011 18.5 0.6 0.22 11.0 0.8 2.9 2 1 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Na_H_Exchanger PF00999.21 CDJ89025.1 - 1.2e-25 90.2 38.0 1.9e-25 89.5 38.0 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF5446 PF17522.2 CDJ89029.1 - 6 7.1 12.4 0.76 10.0 1.9 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5446) ABC_tran_CTD PF16326.5 CDJ89029.1 - 6.6 7.1 13.4 0.24 11.6 2.4 2.6 2 1 0 2 2 2 0 ABC transporter C-terminal domain YojJ PF10372.9 CDJ89029.1 - 9.1 6.5 8.9 26 5.0 0.6 3.2 2 1 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus DmpG_comm PF07836.11 CDJ89030.1 - 1.3 8.6 7.4 3 7.4 0.2 3.2 3 1 0 3 3 3 0 DmpG-like communication domain Motile_Sperm PF00635.26 CDJ89031.1 - 6.5e-17 61.4 0.4 7.6e-17 61.1 0.4 1.1 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF5001 PF16392.5 CDJ89031.1 - 0.0054 16.6 0.0 0.0077 16.1 0.0 1.3 1 0 0 1 1 1 1 Ig-like domain Cytadhesin_P30 PF07271.11 CDJ89031.1 - 0.0094 15.6 1.0 0.0095 15.5 1.0 1.0 1 0 0 1 1 1 1 Cytadhesin P30/P32 HlyIII PF03006.20 CDJ89033.1 - 1e-40 139.9 23.7 1.2e-40 139.6 23.7 1.0 1 0 0 1 1 1 1 Haemolysin-III related Arm_2 PF04826.13 CDJ89034.1 - 8.1e-12 45.1 0.0 1.2e-11 44.6 0.0 1.4 1 1 0 1 1 1 1 Armadillo-like RabGAP-TBC PF00566.18 CDJ89035.1 - 1.2e-33 116.6 7.4 1.4e-33 116.3 2.9 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 CDJ89035.1 - 1.1e-32 112.9 0.0 1.7e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Rab-binding domain (RBD) RUN PF02759.19 CDJ89035.1 - 2.5e-18 66.3 0.2 4.8e-18 65.4 0.2 1.5 1 0 0 1 1 1 1 RUN domain Transcrip_reg PF01709.20 CDJ89036.1 - 1.6e-50 171.8 0.1 1.8e-50 171.6 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator Helicase_C_2 PF13307.6 CDJ89037.1 - 5.5e-11 42.9 0.2 9.2e-11 42.2 0.2 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain DUF908 PF06012.12 CDJ89037.1 - 0.15 11.4 0.0 0.16 11.4 0.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) 7TM_GPCR_Srt PF10321.9 CDJ89039.1 - 3.4e-91 305.5 21.8 3.6e-89 298.8 19.8 2.0 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srt 7TM_GPCR_Srx PF10328.9 CDJ89039.1 - 5.3e-10 39.4 21.5 7.2e-10 38.9 21.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DNA_pol3_delt_C PF14840.6 CDJ89039.1 - 0.062 13.6 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term 7TM_GPCR_Srt PF10321.9 CDJ89040.1 - 3.4e-33 115.0 1.6 4.2e-33 114.6 1.6 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt PALP PF00291.25 CDJ89042.1 - 7.8e-73 245.4 0.1 8.7e-73 245.3 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SNF2_N PF00176.23 CDJ89043.1 - 7.9e-25 87.3 0.5 7.6e-24 84.1 0.1 2.0 1 1 1 2 2 2 2 SNF2 family N-terminal domain Pkinase PF00069.25 CDJ89044.1 - 1.7e-71 240.7 0.0 2.4e-71 240.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ89044.1 - 4.1e-35 121.3 0.0 5e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ89044.1 - 7.8e-07 28.7 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDJ89044.1 - 1.1e-05 24.9 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDJ89044.1 - 0.00013 20.9 0.0 0.00052 18.9 0.0 1.7 1 1 1 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 CDJ89044.1 - 0.0052 16.4 0.5 0.022 14.3 0.5 1.9 1 1 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.11 CDJ89044.1 - 0.02 13.8 0.1 0.036 13.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.20 CDJ89044.1 - 0.032 13.8 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ABC1 PF03109.16 CDJ89044.1 - 0.037 14.2 0.0 0.099 12.8 0.0 1.6 1 1 0 1 1 1 0 ABC1 family APH PF01636.23 CDJ89044.1 - 0.058 13.3 0.0 0.17 11.8 0.0 1.6 1 1 0 2 2 2 0 Phosphotransferase enzyme family Ion_trans PF00520.31 CDJ89045.1 - 8e-11 41.6 8.8 8e-11 41.6 8.8 1.6 2 1 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 CDJ89045.1 - 0.0081 14.9 0.6 0.0081 14.9 0.6 2.2 2 0 0 2 2 2 1 Polycystin cation channel SET_assoc PF11767.8 CDJ89045.1 - 0.081 12.6 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Destabilase PF05497.12 CDJ89047.1 - 2.1e-20 73.2 9.3 2.7e-20 72.8 9.3 1.1 1 0 0 1 1 1 1 Destabilase RRN3 PF05327.11 CDJ89048.1 - 2e-79 267.7 0.1 1.6e-78 264.7 0.1 1.9 1 1 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 AAA PF00004.29 CDJ89049.1 - 3.7e-17 63.0 0.0 8.3e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CDJ89049.1 - 6.8e-15 55.2 0.1 1.8e-14 53.9 0.1 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CDJ89049.1 - 7.3e-12 45.4 0.0 9.5e-09 35.2 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA_24 PF13479.6 CDJ89049.1 - 5.1e-06 26.3 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ89049.1 - 8.4e-06 26.3 0.0 4.1e-05 24.0 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 CDJ89049.1 - 3.5e-05 23.8 0.0 0.00016 21.7 0.0 1.8 1 1 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 CDJ89049.1 - 8.5e-05 22.8 0.3 0.055 13.7 0.0 2.8 2 2 1 3 3 3 2 AAA domain AAA_assoc_2 PF16193.5 CDJ89049.1 - 0.00045 20.5 0.1 0.0012 19.1 0.1 1.9 1 1 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 CDJ89049.1 - 0.00047 20.0 0.0 0.0012 18.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 CDJ89049.1 - 0.00054 19.4 0.0 0.0077 15.7 0.0 2.1 1 1 0 2 2 2 1 Bacterial TniB protein RuvB_N PF05496.12 CDJ89049.1 - 0.00068 19.4 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 CDJ89049.1 - 0.00069 18.9 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 CDJ89049.1 - 0.00087 19.3 0.0 0.0029 17.6 0.0 1.9 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) DEAD PF00270.29 CDJ89049.1 - 0.0014 18.5 0.1 0.8 9.5 0.0 2.6 2 1 1 3 3 3 1 DEAD/DEAH box helicase IstB_IS21 PF01695.17 CDJ89049.1 - 0.0024 17.6 0.0 0.0067 16.2 0.0 1.6 1 1 0 1 1 1 1 IstB-like ATP binding protein ResIII PF04851.15 CDJ89049.1 - 0.0069 16.4 0.0 0.056 13.4 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 CDJ89049.1 - 0.0097 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CDJ89049.1 - 0.0098 15.9 0.0 0.027 14.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 CDJ89049.1 - 0.011 15.1 0.0 0.038 13.4 0.0 1.9 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 CDJ89049.1 - 0.014 15.0 0.0 0.04 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 CDJ89049.1 - 0.015 14.5 0.0 0.032 13.4 0.0 1.6 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_2 PF07724.14 CDJ89049.1 - 0.027 14.6 0.0 0.2 11.8 0.0 2.3 2 1 1 3 3 2 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 CDJ89049.1 - 0.029 14.7 0.0 0.11 12.9 0.0 2.0 2 0 0 2 2 1 0 RNA helicase DNA_pol3_gamma3 PF12169.8 CDJ89049.1 - 0.034 14.1 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III DNA_pol3_delta PF06144.13 CDJ89049.1 - 0.044 13.6 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DUF2075 PF09848.9 CDJ89049.1 - 0.056 12.7 0.0 1.9 7.6 0.0 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Kinesin PF00225.23 CDJ89049.1 - 0.062 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinesin motor domain AAA_19 PF13245.6 CDJ89049.1 - 0.076 13.4 0.0 0.15 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CDJ89049.1 - 0.076 13.6 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CDJ89049.1 - 0.083 12.6 0.1 0.25 11.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 CDJ89049.1 - 0.099 12.1 0.0 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.6 CDJ89049.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 CDJ89049.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SSE PF00437.20 CDJ89049.1 - 0.15 11.1 0.0 0.44 9.5 0.0 1.8 1 1 0 1 1 1 0 Type II/IV secretion system protein Zip PF02535.22 CDJ89050.1 - 1.6e-76 257.7 9.0 1.6e-76 257.7 9.0 2.2 2 0 0 2 2 2 1 ZIP Zinc transporter GRP PF07172.11 CDJ89050.1 - 0.0027 18.4 5.9 0.0027 18.4 5.9 3.1 3 1 0 3 3 3 1 Glycine rich protein family DUF4834 PF16118.5 CDJ89050.1 - 0.014 16.3 1.8 1.8 9.6 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) DUF913 PF06025.12 CDJ89050.1 - 0.096 11.7 0.5 0.45 9.5 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) RNA_polI_A34 PF08208.11 CDJ89050.1 - 1.2 9.2 12.1 0.052 13.6 2.3 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF202 PF02656.15 CDJ89050.1 - 1.4 9.4 0.0 1.4 9.4 0.0 4.0 5 1 0 5 5 5 0 Domain of unknown function (DUF202) DUF1180 PF06679.12 CDJ89050.1 - 2.3 8.6 3.4 14 6.0 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1180) ubiquitin PF00240.23 CDJ89051.1 - 6.3e-270 871.7 43.2 5.1e-33 112.6 0.4 8.0 8 0 0 8 8 8 8 Ubiquitin family Rad60-SLD PF11976.8 CDJ89051.1 - 2.1e-125 408.7 46.7 5e-15 55.1 0.5 8.0 8 0 0 8 8 8 8 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDJ89051.1 - 1.2e-44 150.7 21.8 0.00093 19.6 0.1 10.3 8 8 0 8 8 8 8 Ubiquitin-like domain TBK1_ULD PF18396.1 CDJ89051.1 - 4.7e-28 96.9 16.0 0.1 12.5 0.0 8.2 8 0 0 8 8 8 8 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CDJ89051.1 - 1.6e-26 92.5 26.1 0.08 13.3 0.1 8.1 8 0 0 8 8 8 8 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDJ89051.1 - 3.2e-25 88.4 14.2 0.31 11.2 0.0 9.1 8 0 0 8 8 8 8 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CDJ89051.1 - 7.1e-24 84.4 7.6 0.98 10.0 0.0 8.2 1 1 0 8 8 8 8 DUF2407 ubiquitin-like domain Big_7 PF17957.1 CDJ89051.1 - 1.2e-19 70.8 0.6 7.7 7.4 0.0 8.2 8 0 0 8 8 8 8 Bacterial Ig domain DUF2870 PF11069.8 CDJ89051.1 - 1.9e-11 44.2 0.0 70 3.9 0.0 8.8 8 0 0 8 8 8 0 Protein of unknown function (DUF2870) UDP-g_GGTase PF06427.11 CDJ89051.1 - 1e-09 38.5 16.5 11 6.1 0.0 7.8 8 0 0 8 8 8 0 UDP-glucose:Glycoprotein Glucosyltransferase Big_3_3 PF13750.6 CDJ89051.1 - 1.1e-09 38.1 0.1 60 3.2 0.0 7.7 8 0 0 8 8 8 0 Bacterial Ig-like domain (group 3) DUF3861 PF12977.7 CDJ89051.1 - 3.1e-08 33.7 14.3 41 4.4 0.0 8.1 8 0 0 8 8 8 0 Domain of Unknown Function with PDB structure (DUF3861) DUF969 PF06149.12 CDJ89051.1 - 3.5e-08 33.1 1.2 55 3.1 0.0 7.6 8 0 0 8 8 8 0 Protein of unknown function (DUF969) Ubiquitin_4 PF18036.1 CDJ89051.1 - 9.5e-08 32.0 58.9 40 4.4 0.2 15.7 16 0 0 16 16 16 0 Ubiquitin-like domain ORF11CD3 PF10549.9 CDJ89051.1 - 1.1e-06 28.7 0.0 2.2e+02 2.1 0.0 8.2 8 0 0 8 8 8 0 ORF11CD3 domain PDGLE PF13190.6 CDJ89051.1 - 3e-05 23.8 21.0 40 4.2 0.1 8.8 1 1 4 8 8 8 0 PDGLE domain ACT_5 PF13710.6 CDJ89051.1 - 0.00023 20.9 14.1 1e+02 2.8 0.0 8.0 8 0 0 8 8 8 0 ACT domain ProRS-C_2 PF09181.10 CDJ89051.1 - 0.079 13.1 19.3 1.8e+02 2.4 0.1 7.8 8 0 0 8 8 8 0 Prolyl-tRNA synthetase, C-terminal DUF4704 PF15787.5 CDJ89052.1 - 2.2e-85 286.3 0.7 2.2e-85 286.3 0.7 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4704) DUF1088 PF06469.11 CDJ89052.1 - 1.1e-50 171.6 4.4 2.5e-50 170.4 4.4 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) Laminin_G_3 PF13385.6 CDJ89052.1 - 3.7e-12 46.6 0.0 6.9e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4800 PF16057.5 CDJ89052.1 - 0.00019 20.8 0.3 0.00053 19.3 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) UNC45-central PF11701.8 CDJ89052.1 - 0.056 13.4 0.1 4.4 7.2 0.0 2.7 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central IGF2_C PF08365.11 CDJ89052.1 - 0.062 13.3 0.2 0.17 12.0 0.2 1.8 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide ANF_receptor PF01094.28 CDJ89053.1 - 9.7e-13 47.9 0.0 1.4e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region RVT_1 PF00078.27 CDJ89054.1 - 5.7e-19 68.5 0.0 7.5e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SRP54 PF00448.22 CDJ89055.1 - 7.8e-78 260.6 0.1 1.3e-77 259.8 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 CDJ89055.1 - 4.1e-30 104.3 1.1 4.1e-30 104.3 1.1 4.0 2 1 1 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 CDJ89055.1 - 3.8e-20 71.9 2.0 1.4e-19 70.0 2.0 2.1 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 CDJ89055.1 - 6.9e-07 29.0 0.6 1.1e-05 25.1 0.6 2.5 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CDJ89055.1 - 3.4e-05 24.0 0.0 6.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 CDJ89055.1 - 6.7e-05 22.9 0.0 0.00019 21.5 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 CDJ89055.1 - 0.00066 19.7 0.1 0.0029 17.6 0.1 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2209 PF09974.9 CDJ89055.1 - 0.0008 19.7 0.3 0.0022 18.3 0.3 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2209) AAA_17 PF13207.6 CDJ89055.1 - 0.0019 18.7 0.1 0.0076 16.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ89055.1 - 0.0019 18.6 0.0 0.0038 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain CLP1_P PF16575.5 CDJ89055.1 - 0.0021 17.9 0.3 0.57 9.9 0.1 2.7 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop SRPRB PF09439.10 CDJ89055.1 - 0.0034 16.9 1.9 0.73 9.2 0.0 2.7 2 1 0 3 3 3 2 Signal recognition particle receptor beta subunit Zeta_toxin PF06414.12 CDJ89055.1 - 0.0044 16.3 0.0 0.011 15.0 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin APS_kinase PF01583.20 CDJ89055.1 - 0.0053 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase MeaB PF03308.16 CDJ89055.1 - 0.0079 15.2 0.2 0.15 11.0 0.0 2.8 3 1 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_31 PF13614.6 CDJ89055.1 - 0.017 15.1 0.0 0.05 13.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 CDJ89055.1 - 0.017 14.9 0.5 0.21 11.4 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 CDJ89055.1 - 0.022 14.8 2.9 0.087 12.9 0.3 3.2 3 1 0 3 3 3 0 50S ribosome-binding GTPase MobB PF03205.14 CDJ89055.1 - 0.028 14.3 0.1 0.17 11.8 0.0 2.3 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 CDJ89055.1 - 0.03 14.6 0.1 0.16 12.3 0.1 2.3 2 1 0 2 2 1 0 AAA domain AAA_30 PF13604.6 CDJ89055.1 - 0.037 13.8 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CDJ89055.1 - 0.043 14.2 2.0 0.52 10.7 0.1 3.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 CDJ89055.1 - 0.044 14.1 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 CDJ89055.1 - 0.053 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 6-phosphofructo-2-kinase PduV-EutP PF10662.9 CDJ89055.1 - 0.057 13.2 0.3 2.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNase_H2-Ydr279 PF09468.10 CDJ89056.1 - 8.1e-06 26.1 4.2 7.6e-05 23.0 4.2 2.5 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 CDJ89056.1 - 0.0088 16.3 0.0 0.027 14.7 0.0 1.9 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain MRP-S33 PF08293.11 CDJ89057.1 - 2.5e-18 66.1 0.1 3e-18 65.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 PNK3P PF08645.11 CDJ89058.1 - 4.9e-56 188.9 0.2 2.2e-55 186.8 0.1 1.9 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 CDJ89058.1 - 4.9e-18 65.7 0.2 1.4e-09 38.2 0.1 2.4 1 1 1 2 2 2 2 AAA domain KTI12 PF08433.10 CDJ89058.1 - 1e-06 28.4 1.4 0.018 14.5 0.0 2.3 1 1 0 2 2 2 2 Chromatin associated protein KTI12 AAA_25 PF13481.6 CDJ89058.1 - 0.00013 21.6 0.0 0.00033 20.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CDJ89058.1 - 0.00066 20.0 0.1 0.0077 16.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CDJ89058.1 - 0.001 18.4 0.1 0.032 13.5 0.0 2.3 1 1 1 2 2 2 1 Zeta toxin AAA_18 PF13238.6 CDJ89058.1 - 0.0014 19.2 0.1 0.018 15.5 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.6 CDJ89058.1 - 0.0016 18.9 0.0 0.0047 17.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CDJ89058.1 - 0.0074 16.6 0.0 0.023 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CDJ89058.1 - 0.017 14.9 0.0 0.049 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDJ89058.1 - 0.02 15.4 0.0 0.11 13.0 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 CDJ89058.1 - 0.039 13.7 0.0 1.5 8.7 0.0 2.9 3 0 0 3 3 3 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 CDJ89058.1 - 0.049 13.4 0.2 0.17 11.6 0.2 2.0 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 CDJ89058.1 - 0.056 13.5 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase 6PF2K PF01591.18 CDJ89058.1 - 0.056 12.7 0.1 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 6-phosphofructo-2-kinase NACHT PF05729.12 CDJ89058.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain HAD_2 PF13419.6 CDJ89058.1 - 0.064 13.3 1.0 7 6.7 0.3 2.9 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase AAA_16 PF13191.6 CDJ89058.1 - 0.091 13.1 0.1 0.23 11.8 0.0 1.6 1 1 1 2 2 2 0 AAA ATPase domain CobU PF02283.16 CDJ89058.1 - 0.093 12.3 0.0 6.8 6.2 0.0 2.4 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase cobW PF02492.19 CDJ89058.1 - 0.12 11.9 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Hydrolase_6 PF13344.6 CDJ89058.1 - 0.14 12.3 0.1 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDJ89058.1 - 0.21 11.8 1.7 2.4 8.4 0.3 2.4 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Tetraspanin PF00335.20 CDJ89059.1 - 0.00017 21.4 20.6 0.032 13.9 20.6 2.0 1 1 0 1 1 1 1 Tetraspanin family MAP17 PF15807.5 CDJ89059.1 - 0.081 13.2 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 GWT1 PF06423.12 CDJ89059.1 - 0.12 12.5 9.2 0.16 12.1 0.5 2.1 1 1 1 2 2 2 0 GWT1 TctB PF07331.11 CDJ89059.1 - 0.21 11.9 6.7 1.1 9.5 6.5 1.9 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family EphA2_TM PF14575.6 CDJ89059.1 - 2.6 9.0 4.5 19 6.2 0.0 3.4 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain DUF805 PF05656.14 CDJ89059.1 - 4.9 7.6 5.9 27 5.2 5.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF805) ETRAMP PF09716.10 CDJ89059.1 - 5.8 7.0 7.6 13 5.9 2.8 2.8 2 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Lustrin_cystein PF14625.6 CDJ89061.1 - 4.7 7.7 17.1 42 4.6 15.0 2.9 2 1 0 2 2 2 0 Lustrin, cysteine-rich repeated domain MIP PF00230.20 CDJ89062.1 - 7.9e-45 153.3 8.9 9.6e-45 153.0 8.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein ThrE PF06738.12 CDJ89062.1 - 0.43 9.9 10.1 0.36 10.2 0.1 2.7 1 1 1 2 2 2 0 Putative threonine/serine exporter Transgly_assoc PF04226.13 CDJ89062.1 - 3.7 7.9 13.0 1.8 8.9 0.3 4.1 4 0 0 4 4 4 0 Transglycosylase associated protein PAS_11 PF14598.6 CDJ89063.1 - 1.3e-16 60.7 0.1 2.6e-12 46.9 0.1 2.2 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 CDJ89063.1 - 5.6e-13 48.9 0.0 5.7e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 CDJ89063.1 - 4.5e-09 36.5 0.0 2.2e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 CDJ89063.1 - 1.7e-05 25.0 0.0 0.3 11.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 CDJ89063.1 - 6.6e-05 23.1 0.0 0.0072 16.6 0.0 2.5 2 0 0 2 2 2 1 PAS domain SAM_2 PF07647.17 CDJ89065.1 - 6.9e-26 90.2 0.2 3.9e-15 55.7 0.1 2.8 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CDJ89065.1 - 1.1e-18 67.4 0.6 1.1e-15 57.8 0.2 2.6 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) TIR_2 PF13676.6 CDJ89065.1 - 7.9e-11 42.6 0.1 7.8e-10 39.4 0.0 2.3 2 0 0 2 2 2 1 TIR domain RUN PF02759.19 CDJ89065.1 - 0.037 14.0 0.6 0.13 12.2 0.1 2.2 3 0 0 3 3 3 0 RUN domain DUF3361 PF11841.8 CDJ89065.1 - 0.055 13.4 2.2 0.18 11.7 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) CLPTM1 PF05602.12 CDJ89066.1 - 8.5e-15 54.7 0.2 9.1e-15 54.6 0.2 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF3978 PF13123.6 CDJ89067.1 - 0.1 12.3 0.2 0.19 11.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3978) Pom PF17251.2 CDJ89067.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Protochlamydia outer membrane protein dCache_2 PF08269.11 CDJ89067.1 - 3 6.9 7.3 4.8 6.3 7.3 1.3 1 0 0 1 1 1 0 Cache domain DUF4094 PF13334.6 CDJ89067.1 - 3.7 8.0 12.1 5.8 7.4 1.5 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4094) CorA PF01544.18 CDJ89067.1 - 4.5 6.5 12.5 11 5.2 11.2 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Retrotrans_gag PF03732.17 CDJ89068.1 - 0.016 15.5 0.8 0.075 13.3 0.0 2.3 1 1 1 2 2 2 0 Retrotransposon gag protein Gag_p17 PF00540.18 CDJ89068.1 - 0.058 13.4 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) Ion_trans_2 PF07885.16 CDJ89070.1 - 2.8e-30 104.1 21.1 7.8e-19 67.4 4.9 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 CDJ89070.1 - 0.0017 17.7 12.8 0.013 14.7 1.3 2.2 2 0 0 2 2 2 2 Ion transport protein IRK PF01007.20 CDJ89070.1 - 0.13 12.1 2.7 0.63 9.8 0.2 2.5 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain Transket_pyr PF02779.24 CDJ89071.1 - 2e-40 138.4 0.0 2.9e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CDJ89071.1 - 5.7e-35 119.9 0.0 1.1e-34 119.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DFRP_C PF16543.5 CDJ89071.1 - 1.4e-21 76.8 7.3 1.4e-21 76.8 7.3 3.2 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 CDJ89071.1 - 7e-07 29.9 21.5 6e-05 23.7 8.6 4.0 2 1 1 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 CDJ89071.1 - 6.9e-05 22.8 7.8 6.9e-05 22.8 7.8 3.3 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 CDJ89071.1 - 0.00011 21.9 11.2 0.00031 20.5 2.2 3.4 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH PF00642.24 CDJ89071.1 - 0.00033 20.5 1.7 0.00033 20.5 1.7 3.2 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CVNH PF08881.10 CDJ89071.1 - 0.38 11.5 2.9 4.2 8.1 0.9 2.4 2 0 0 2 2 2 0 CVNH domain zf-CCCH_3 PF15663.5 CDJ89071.1 - 0.69 10.2 8.7 1.9 8.7 1.7 2.9 1 1 1 2 2 2 0 Zinc-finger containing family Phage_B PF02304.15 CDJ89071.1 - 0.73 10.2 5.4 9.5 6.6 1.0 2.5 2 0 0 2 2 2 0 Scaffold protein B Got1 PF04178.12 CDJ89072.1 - 4.6e-15 56.0 7.9 8.5e-15 55.2 7.9 1.4 1 0 0 1 1 1 1 Got1/Sft2-like family FERM_C PF09380.10 CDJ89073.1 - 2e-19 69.7 0.2 8.6e-19 67.7 0.2 1.9 1 1 0 1 1 1 1 FERM C-terminal PH-like domain DUF3338 PF11819.8 CDJ89073.1 - 3.4e-18 65.9 2.3 3.9e-18 65.7 1.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3338) FERM_N PF09379.10 CDJ89073.1 - 1.5e-10 40.8 0.0 9.4e-10 38.3 0.0 2.2 2 0 0 2 2 2 1 FERM N-terminal domain FERM_M PF00373.18 CDJ89073.1 - 5e-10 39.8 0.0 1.6e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 FERM central domain HTH_48 PF17906.1 CDJ89074.1 - 1.1e-11 44.7 3.4 6.1e-11 42.3 3.4 2.1 1 1 0 1 1 1 1 HTH domain in Mos1 transposase HTH_38 PF13936.6 CDJ89074.1 - 2.1e-06 27.4 0.0 4.5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 CDJ89074.1 - 6.5e-05 23.5 0.0 0.0001 22.9 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 CDJ89074.1 - 0.00012 22.3 0.1 0.00022 21.4 0.1 1.4 1 0 0 1 1 1 1 Transposase HTH_50 PF18024.1 CDJ89074.1 - 0.00018 21.0 0.0 0.00042 19.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_IS630 PF01710.16 CDJ89074.1 - 0.0004 20.4 0.0 0.00044 20.3 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 CDJ89074.1 - 0.00093 18.9 0.2 0.01 15.6 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 CDJ89074.1 - 0.0011 19.0 0.5 0.27 11.4 0.0 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_11 PF08279.12 CDJ89074.1 - 0.0034 17.3 0.1 0.0063 16.4 0.1 1.5 1 0 0 1 1 1 1 HTH domain TnsD PF15978.5 CDJ89074.1 - 0.022 13.7 0.1 0.028 13.4 0.1 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D CENP-B_N PF04218.13 CDJ89074.1 - 0.029 14.0 0.1 0.052 13.2 0.1 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_29 PF13551.6 CDJ89074.1 - 0.038 14.0 0.0 0.22 11.6 0.0 2.0 1 1 1 2 2 2 0 Winged helix-turn helix IF2_N PF04760.15 CDJ89074.1 - 0.07 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region HTH_24 PF13412.6 CDJ89074.1 - 0.09 12.4 0.0 0.21 11.2 0.0 1.6 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 CDJ89074.1 - 0.099 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain HTH_17 PF12728.7 CDJ89074.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_5 PF01022.20 CDJ89074.1 - 0.12 12.3 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_36 PF13730.6 CDJ89074.1 - 0.13 12.3 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain NUMOD1 PF07453.13 CDJ89074.1 - 0.15 12.4 0.5 0.25 11.6 0.1 1.6 2 0 0 2 2 1 0 NUMOD1 domain GPAT_N PF14829.6 CDJ89075.1 - 0.0031 17.5 0.0 0.0058 16.6 0.0 1.4 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase N-terminal Pmp3 PF01679.17 CDJ89077.1 - 1.6e-18 66.6 14.7 2.8e-18 65.8 14.7 1.4 1 0 0 1 1 1 1 Proteolipid membrane potential modulator phiKZ_IP PF12699.7 CDJ89077.1 - 0.0037 16.5 0.1 0.007 15.6 0.1 1.4 1 0 0 1 1 1 1 phiKZ-like phage internal head proteins ODR4-like PF14778.6 CDJ89078.1 - 6.7e-16 58.2 0.0 7.9e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Olfactory receptor 4-like KH_1 PF00013.29 CDJ89079.1 - 9.6e-47 156.7 19.3 6.8e-14 51.4 0.1 5.6 5 1 0 5 5 5 5 KH domain KH_2 PF07650.17 CDJ89079.1 - 1.4e-10 40.9 18.3 0.0015 18.3 1.8 4.4 3 1 1 4 4 4 4 KH domain KH_4 PF13083.6 CDJ89079.1 - 1.1e-06 28.4 7.3 0.0012 18.6 0.2 4.2 4 0 0 4 4 4 3 KH domain KH_5 PF13184.6 CDJ89079.1 - 6.3e-05 23.0 11.7 0.45 10.6 0.2 4.0 4 0 0 4 4 4 3 NusA-like KH domain CobT PF06213.12 CDJ89079.1 - 0.25 10.7 5.2 2.3 7.6 0.0 2.5 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT HTH_48 PF17906.1 CDJ89080.1 - 3.8e-06 26.9 0.0 4.6e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 HTH domain in Mos1 transposase HTH_5 PF01022.20 CDJ89080.1 - 1.1e-05 25.2 0.1 1.9e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_28 PF13518.6 CDJ89080.1 - 0.00013 22.0 0.2 0.62 10.2 0.1 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_50 PF18024.1 CDJ89080.1 - 0.00013 21.5 0.9 0.0003 20.3 0.3 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 CDJ89080.1 - 0.00023 20.7 0.1 0.00043 19.8 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_32 PF13565.6 CDJ89080.1 - 0.00045 20.8 0.1 0.00097 19.7 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 CDJ89080.1 - 0.00095 19.4 2.1 0.0017 18.5 2.1 1.5 1 0 0 1 1 1 1 Transposase MarR PF01047.22 CDJ89080.1 - 0.0031 17.4 0.1 0.0055 16.6 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.12 CDJ89080.1 - 0.0059 16.5 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 HTH domain MarR_2 PF12802.7 CDJ89080.1 - 0.0067 16.3 0.1 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 CDJ89080.1 - 0.0069 16.3 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_Tnp_IS630 PF01710.16 CDJ89080.1 - 0.01 15.9 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 Transposase NUMOD1 PF07453.13 CDJ89080.1 - 0.011 16.0 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 0 NUMOD1 domain HTH_6 PF01418.17 CDJ89080.1 - 0.016 15.2 0.0 0.27 11.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family HTH_1 PF00126.27 CDJ89080.1 - 0.016 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_36 PF13730.6 CDJ89080.1 - 0.037 14.0 0.1 0.074 13.0 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 CDJ89080.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_DeoR PF08220.12 CDJ89080.1 - 0.083 12.7 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_20 PF12840.7 CDJ89080.1 - 0.093 12.8 0.0 0.26 11.4 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain Fe_dep_repress PF01325.19 CDJ89080.1 - 0.16 12.2 0.1 0.31 11.2 0.1 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Sigma70_r4_2 PF08281.12 CDJ89080.1 - 0.27 10.9 0.9 1.2 8.8 0.1 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 LRR_8 PF13855.6 CDJ89081.1 - 1.9e-57 190.9 65.4 2.9e-17 62.2 3.5 7.1 2 1 6 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 CDJ89081.1 - 1.9e-30 104.4 42.0 2.9e-09 37.0 1.8 7.9 5 1 5 10 10 10 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CDJ89081.1 - 1.7e-17 63.6 3.1 2e-11 44.0 0.5 3.7 2 1 3 5 5 5 4 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 CDJ89081.1 - 5.6e-12 45.5 17.1 5.3e-07 29.3 1.5 4.3 1 1 4 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.33 CDJ89081.1 - 6.8e-09 35.1 33.5 1.2 10.0 0.0 11.5 11 2 1 12 12 12 3 Leucine Rich Repeat LRR_6 PF13516.6 CDJ89081.1 - 9e-08 31.6 25.4 0.089 12.9 0.1 9.2 10 0 0 10 10 10 4 Leucine Rich repeat POB3_N PF17292.2 CDJ89081.1 - 0.1 13.1 0.1 0.41 11.1 0.0 2.1 2 0 0 2 2 2 0 POB3-like N-terminal PH domain PRCC PF10253.9 CDJ89082.1 - 2.7e-21 77.4 5.5 4.3e-20 73.4 5.5 2.5 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting zf-CCCH PF00642.24 CDJ89083.1 - 5.1e-12 45.4 29.5 2.7e-06 27.1 0.4 4.7 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ89083.1 - 8.8e-09 35.1 10.7 1.1e-06 28.5 2.6 6.0 6 0 0 6 6 6 2 Zinc finger domain Torus PF16131.5 CDJ89083.1 - 8.3e-08 32.9 33.5 0.00068 20.3 0.5 5.7 1 1 4 6 6 6 3 Torus domain zf-CCCH_4 PF18044.1 CDJ89083.1 - 4.8e-06 26.2 0.3 4.8e-06 26.2 0.3 4.9 6 0 0 6 6 5 2 CCCH-type zinc finger zf-CCHC PF00098.23 CDJ89083.1 - 0.00013 21.8 5.7 0.00013 21.8 5.7 4.1 4 0 0 4 4 4 2 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ89083.1 - 0.0054 16.7 8.5 0.099 12.6 1.0 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCCH_3 PF15663.5 CDJ89083.1 - 0.15 12.2 31.7 0.091 13.0 9.6 4.5 1 1 2 3 3 3 0 Zinc-finger containing family zf-C3H1 PF10650.9 CDJ89083.1 - 0.23 11.2 13.4 3.6 7.4 0.6 4.1 3 0 0 3 3 3 0 Putative zinc-finger domain zf-CCCH_2 PF14608.6 CDJ89083.1 - 0.53 10.8 42.9 0.63 10.6 1.0 5.8 6 1 0 6 6 5 0 RNA-binding, Nab2-type zinc finger zf-CCHC_4 PF14392.6 CDJ89083.1 - 2.8 7.8 15.4 1.6 8.5 1.2 2.7 2 0 0 2 2 2 0 Zinc knuckle Opy2 PF09463.10 CDJ89083.1 - 5.3 7.4 17.3 4.5 7.7 0.2 5.3 4 1 2 6 6 5 0 Opy2 protein zf-C3HC4_2 PF13923.6 CDJ89084.1 - 4.9e-08 32.7 11.4 9.3e-08 31.8 11.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ89084.1 - 8.8e-08 31.9 11.5 1.7e-07 31.0 11.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ89084.1 - 0.00014 21.6 9.1 0.00026 20.8 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ89084.1 - 0.0003 20.8 4.3 0.0003 20.8 4.3 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CDJ89084.1 - 0.00069 19.9 10.3 0.0014 19.0 10.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CDJ89084.1 - 0.00072 19.5 11.0 0.00072 19.5 11.0 2.0 2 0 0 2 2 2 1 zinc-RING finger domain RAWUL PF16207.5 CDJ89084.1 - 0.0029 18.2 0.1 0.0067 17.1 0.1 1.6 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_4 PF15227.6 CDJ89084.1 - 0.015 15.4 12.4 0.034 14.3 12.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 CDJ89084.1 - 0.57 10.0 8.9 1.6 8.6 8.9 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 CDJ89084.1 - 0.59 10.5 7.2 1.6 9.1 7.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_5 PF17121.5 CDJ89084.1 - 1.6 8.7 8.9 0.9 9.5 6.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHC2_SAM_assoc PF16616.5 CDJ89084.1 - 2.7 8.8 7.8 0.91 10.4 4.6 1.8 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Prok-RING_4 PF14447.6 CDJ89084.1 - 4.2 7.3 14.0 15 5.6 13.4 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF1751 PF08551.10 CDJ89085.1 - 4.4e-05 24.0 4.3 0.00011 22.7 4.3 1.7 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Claudin_3 PF06653.11 CDJ89085.1 - 0.12 12.3 8.3 0.023 14.7 4.5 1.7 2 0 0 2 2 2 0 Tight junction protein, Claudin-like RasGEF PF00617.19 CDJ89086.1 - 1.5e-39 136.1 0.0 4.5e-39 134.5 0.0 1.9 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CDJ89086.1 - 8e-31 106.4 2.5 1.6e-30 105.4 0.1 2.8 3 0 0 3 3 3 1 RasGEF N-terminal motif PH PF00169.29 CDJ89086.1 - 8.4e-09 35.9 0.1 2.6e-08 34.3 0.1 1.8 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.20 CDJ89086.1 - 0.00074 19.8 1.4 0.00074 19.8 1.4 3.3 3 0 0 3 3 3 1 RhoGEF domain PH_10 PF15411.6 CDJ89086.1 - 0.042 14.1 5.7 1.5 9.1 0.1 3.4 2 1 1 3 3 3 0 Pleckstrin homology domain Mad3_BUB1_I PF08311.12 CDJ89086.1 - 1.1 9.3 5.3 2.7 8.0 0.8 3.7 4 0 0 4 4 4 0 Mad3/BUB1 homology region 1 CMAS PF02353.20 CDJ89089.1 - 4e-10 39.5 0.4 4.4e-10 39.3 0.4 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Glyco_hydro_2_N PF02837.18 CDJ89090.1 - 0.053 13.4 0.0 0.068 13.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain PI-PLC-X PF00388.19 CDJ89091.1 - 3.7e-50 169.3 0.0 5.2e-50 168.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CDJ89091.1 - 6.2e-28 97.5 0.0 9.4e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 CDJ89091.1 - 1.1e-19 70.7 0.0 1.8e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 C2 domain GDPD PF03009.17 CDJ89091.1 - 0.016 15.0 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family VWA PF00092.28 CDJ89092.1 - 4.1e-46 157.4 7.4 8.1e-19 68.5 0.1 5.1 5 0 0 5 5 5 4 von Willebrand factor type A domain VWA_2 PF13519.6 CDJ89092.1 - 6.1e-22 78.3 2.4 2.4e-05 24.9 0.0 5.2 5 0 0 5 5 5 3 von Willebrand factor type A domain FXa_inhibition PF14670.6 CDJ89092.1 - 1.3e-06 28.5 10.2 3.8e-06 27.1 10.2 1.9 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site fn3 PF00041.21 CDJ89092.1 - 0.00014 22.1 1.2 0.00023 21.4 0.1 1.9 2 0 0 2 2 2 1 Fibronectin type III domain EGF_CA PF07645.15 CDJ89092.1 - 0.00073 19.7 5.7 0.0017 18.5 5.7 1.7 1 0 0 1 1 1 1 Calcium-binding EGF domain DUF3437 PF11919.8 CDJ89093.1 - 5e-16 58.4 0.0 3.1e-15 55.8 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) Pkinase PF00069.25 CDJ89096.1 - 7.5e-49 166.5 0.0 9.2e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ89096.1 - 4.6e-23 81.8 0.1 1.8e-22 79.9 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ89096.1 - 0.0015 17.4 0.0 0.0022 16.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CDJ89096.1 - 0.0064 15.5 0.0 0.0087 15.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CDJ89096.1 - 0.017 14.5 0.0 0.031 13.6 0.0 1.4 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 CDJ89096.1 - 0.03 14.2 0.3 0.11 12.4 0.1 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 CDJ89096.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 CDJ89096.1 - 0.17 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RhoGEF PF00621.20 CDJ89098.1 - 2.2e-39 135.6 0.3 5.4e-39 134.3 0.3 1.7 1 0 0 1 1 1 1 RhoGEF domain DUF272 PF03312.15 CDJ89099.1 - 1e-11 45.2 0.0 1.3e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF272) Mac-1 PF09028.10 CDJ89099.1 - 0.028 13.5 0.0 0.036 13.1 0.0 1.1 1 0 0 1 1 1 0 Mac 1 TROVE PF05731.11 CDJ89100.1 - 4.7e-81 273.1 0.1 1.4e-78 265.0 0.1 2.2 1 1 0 1 1 1 1 TROVE domain SH2 PF00017.24 CDJ89100.1 - 0.048 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 SH2 domain ResIII PF04851.15 CDJ89101.1 - 0.0065 16.5 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Retrotrans_gag PF03732.17 CDJ89101.1 - 0.033 14.5 0.1 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein Helicase_RecD PF05127.14 CDJ89101.1 - 0.077 12.8 1.4 0.15 11.9 0.1 2.2 3 0 0 3 3 3 0 Helicase AAA_19 PF13245.6 CDJ89101.1 - 0.13 12.6 0.4 0.39 11.1 0.1 2.0 2 0 0 2 2 2 0 AAA domain GST_C_3 PF14497.6 CDJ89103.1 - 3.1e-16 59.4 0.1 3.7e-16 59.1 0.1 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDJ89103.1 - 3.6e-09 36.7 0.1 4.6e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ABC_membrane PF00664.23 CDJ89104.1 - 5.8e-67 226.2 40.2 7.7e-35 120.9 11.9 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ89104.1 - 4.2e-37 127.7 0.2 1.4e-20 74.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 CDJ89104.1 - 1.6e-06 28.2 0.6 0.027 14.5 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ89104.1 - 2.9e-05 24.1 0.9 0.0022 17.9 0.2 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 CDJ89104.1 - 0.00032 20.4 2.0 0.2 11.5 0.3 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 CDJ89104.1 - 0.0013 18.2 3.8 1.7 8.0 0.4 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDJ89104.1 - 0.0019 18.6 0.3 0.84 10.0 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain Dynamin_N PF00350.23 CDJ89104.1 - 0.002 18.2 4.8 0.033 14.2 0.8 2.5 2 0 0 2 2 2 1 Dynamin family Zeta_toxin PF06414.12 CDJ89104.1 - 0.0047 16.2 1.1 0.12 11.6 0.2 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_21 PF13304.6 CDJ89104.1 - 0.0078 16.1 1.5 0.84 9.4 0.1 2.7 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CDJ89104.1 - 0.014 15.7 0.9 0.87 9.9 0.3 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CDJ89104.1 - 0.028 14.0 0.7 3.1 7.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 CDJ89104.1 - 0.029 14.4 4.3 0.11 12.5 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 CDJ89104.1 - 0.081 11.8 0.1 5.5 5.8 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 CDJ89104.1 - 0.11 12.5 1.6 0.89 9.6 0.4 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 CDJ89104.1 - 0.12 11.5 1.5 3 6.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_15 PF13175.6 CDJ89104.1 - 0.4 10.3 1.9 18 4.9 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 CDJ89104.1 - 0.43 10.8 1.6 19 5.5 0.2 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 CDJ89104.1 - 0.5 9.3 1.6 9.6 5.1 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 CDJ89104.1 - 2 8.9 8.7 3.8 8.0 0.4 2.8 3 0 0 3 3 2 0 AAA domain ABC_membrane PF00664.23 CDJ89105.1 - 1.6e-69 234.6 31.6 6.4e-35 121.1 11.9 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ89105.1 - 6.7e-21 75.3 0.0 1.2e-20 74.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 CDJ89105.1 - 0.00087 19.2 0.2 0.0019 18.1 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 CDJ89105.1 - 0.0063 16.0 0.8 1.5 8.2 0.4 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CDJ89105.1 - 0.009 16.1 0.1 0.024 14.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CDJ89105.1 - 0.015 15.4 0.8 0.03 14.4 0.8 1.5 1 0 0 1 1 1 0 Dynamin family Zeta_toxin PF06414.12 CDJ89105.1 - 0.062 12.6 0.2 0.11 11.8 0.2 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 CDJ89105.1 - 0.071 12.9 0.3 0.17 11.6 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CDJ89105.1 - 0.17 12.2 0.1 0.73 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Ras PF00071.22 CDJ89106.1 - 2.5e-41 141.0 0.1 3.1e-41 140.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ89106.1 - 4.6e-19 68.8 0.1 9.2e-19 67.8 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ89106.1 - 2.9e-08 33.3 0.1 3.7e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDJ89106.1 - 8.3e-05 22.2 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF4623 PF15416.6 CDJ89106.1 - 0.1 11.2 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4623) bact-PGI_C PF10432.9 CDJ89106.1 - 0.12 12.4 0.1 0.19 11.7 0.1 1.4 1 1 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal SIS domain Exo_endo_phos_2 PF14529.6 CDJ89107.1 - 1.6e-06 28.0 0.0 4e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ89107.1 - 0.0033 17.0 1.2 0.0059 16.1 0.1 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Ras PF00071.22 CDJ89108.1 - 2e-12 47.0 0.1 2.3e-12 46.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ89108.1 - 9.3e-12 45.2 0.0 1.1e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 CDJ89108.1 - 0.00013 21.9 0.0 0.00015 21.8 0.0 1.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 CDJ89108.1 - 0.0039 17.1 0.0 0.0041 17.0 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_7 PF12775.7 CDJ89108.1 - 0.0046 16.5 0.1 0.0053 16.3 0.1 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 CDJ89108.1 - 0.0084 15.8 0.0 0.0094 15.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain MCM PF00493.23 CDJ89108.1 - 0.011 14.9 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 0 MCM P-loop domain AAA_22 PF13401.6 CDJ89108.1 - 0.019 15.3 0.0 0.019 15.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 CDJ89108.1 - 0.021 14.2 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 CDJ89108.1 - 0.021 15.2 0.0 0.022 15.1 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 CDJ89108.1 - 0.021 14.7 0.0 0.039 13.9 0.0 1.5 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 CDJ89108.1 - 0.022 15.3 0.1 0.023 15.2 0.1 1.1 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 CDJ89108.1 - 0.024 14.7 0.1 0.027 14.6 0.1 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 CDJ89108.1 - 0.028 14.8 0.0 0.035 14.5 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 CDJ89108.1 - 0.045 14.3 0.1 0.048 14.2 0.1 1.1 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 CDJ89108.1 - 0.046 13.5 0.1 0.054 13.2 0.1 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 CDJ89108.1 - 0.064 13.0 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arf PF00025.21 CDJ89108.1 - 0.12 11.9 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_28 PF13521.6 CDJ89108.1 - 0.13 12.5 0.1 0.13 12.5 0.1 1.1 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CDJ89108.1 - 0.15 11.8 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_21 PF13304.6 CDJ89108.1 - 0.16 11.7 0.2 0.17 11.6 0.2 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Ras PF00071.22 CDJ89109.1 - 6.4e-59 198.2 0.1 8.4e-59 197.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ89109.1 - 1.5e-33 115.6 0.0 2.6e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ89109.1 - 2.1e-13 50.1 0.0 2.9e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ89109.1 - 1.3e-06 28.5 0.0 2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDJ89109.1 - 9e-05 21.9 0.1 0.00016 21.1 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CDJ89109.1 - 9.1e-05 22.1 0.0 0.00031 20.4 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDJ89109.1 - 0.00048 20.1 0.1 0.027 14.4 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CDJ89109.1 - 0.00082 19.7 0.0 0.009 16.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 CDJ89109.1 - 0.0061 16.3 0.0 0.018 14.7 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MCM PF00493.23 CDJ89109.1 - 0.012 14.8 0.0 0.033 13.3 0.0 1.7 3 0 0 3 3 3 0 MCM P-loop domain AAA_16 PF13191.6 CDJ89109.1 - 0.028 14.8 0.1 0.054 13.9 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 CDJ89109.1 - 0.031 14.0 0.1 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CDJ89109.1 - 0.036 14.1 0.0 0.079 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 CDJ89109.1 - 0.051 14.1 0.1 0.084 13.4 0.1 1.5 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 CDJ89109.1 - 0.056 12.8 0.0 0.32 10.4 0.0 2.0 2 1 0 2 2 2 0 Bacterial TniB protein AAA_21 PF13304.6 CDJ89109.1 - 0.058 13.2 0.7 0.071 12.9 0.6 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 CDJ89109.1 - 0.095 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region HTH_48 PF17906.1 CDJ89110.1 - 0.00074 19.6 0.0 0.00099 19.2 0.0 1.2 1 0 0 1 1 1 1 HTH domain in Mos1 transposase zf-C2H2_assoc3 PF16637.5 CDJ89110.1 - 0.13 12.5 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative zinc-finger between two C2H2 zinc-fingers on Patz Ephrin_rec_like PF07699.13 CDJ89111.1 - 0.46 10.3 33.1 0.86 9.4 1.4 6.6 5 2 2 7 7 7 0 Putative ephrin-receptor like Neur_chan_LBD PF02931.23 CDJ89112.1 - 1.3e-39 135.9 0.6 1.7e-39 135.5 0.6 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ89112.1 - 1.2e-20 74.6 6.0 7.7e-18 65.4 3.6 2.2 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Dynactin_p62 PF05502.13 CDJ89113.1 - 6.2e-11 41.7 23.8 3.2e-10 39.4 23.8 1.8 1 1 0 1 1 1 1 Dynactin p62 family DUF4748 PF15932.5 CDJ89114.1 - 6.2e-07 29.1 0.1 1.3e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) Death PF00531.22 CDJ89115.1 - 2.4e-05 24.4 0.0 2.8e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Death domain ApoLp-III PF07464.11 CDJ89117.1 - 0.00026 21.1 2.3 0.0031 17.6 0.5 2.2 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) ISG65-75 PF11727.8 CDJ89117.1 - 0.043 13.0 13.2 0.12 11.5 5.5 2.1 1 1 1 2 2 2 0 Invariant surface glycoprotein LEA_4 PF02987.16 CDJ89117.1 - 0.082 13.0 32.3 0.3 11.2 8.1 4.5 3 1 1 4 4 4 0 Late embryogenesis abundant protein Tape_meas_lam_C PF09718.10 CDJ89117.1 - 0.11 12.7 4.4 3.9 7.7 0.1 2.8 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Mucin PF01456.17 CDJ89117.1 - 0.14 12.1 5.4 0.2 11.7 5.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF883 PF05957.13 CDJ89117.1 - 0.19 12.3 10.6 6.6 7.4 2.5 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Chlorosome_CsmC PF11098.8 CDJ89117.1 - 0.8 9.7 15.8 0.67 9.9 6.9 2.7 1 1 2 3 3 3 0 Chlorosome envelope protein C YtxH PF12732.7 CDJ89117.1 - 1 10.0 18.4 3.1e+03 -1.2 15.6 3.5 2 1 0 2 2 2 0 YtxH-like protein Perilipin PF03036.16 CDJ89117.1 - 2.5 7.1 9.0 4.3 6.2 2.0 2.3 1 1 1 2 2 2 0 Perilipin family Aminotran_5 PF00266.19 CDJ89118.1 - 3.9e-47 161.0 0.0 4.5e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Toxin_TOLIP PF00087.21 CDJ89119.1 - 0.014 15.6 11.2 0.024 14.9 11.2 1.4 1 0 0 1 1 1 0 Snake toxin and toxin-like protein Activin_recp PF01064.23 CDJ89119.1 - 0.024 15.7 7.4 0.045 14.8 7.4 1.5 1 0 0 1 1 1 0 Activin types I and II receptor domain Nop PF01798.18 CDJ89120.1 - 2.2e-83 279.3 0.8 5.3e-83 278.0 0.2 1.9 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CDJ89120.1 - 1.9e-19 69.8 3.7 1.9e-19 69.8 3.7 2.5 3 0 0 3 3 3 1 NOP5NT (NUC127) domain Baculo_PEP_C PF04513.12 CDJ89120.1 - 0.089 12.8 3.6 9 6.3 0.0 2.9 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prot_ATP_ID_OB PF16450.5 CDJ89121.1 - 0.026 14.5 0.0 0.042 13.8 0.0 1.5 1 1 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain Rx_N PF18052.1 CDJ89123.1 - 6.4 7.1 7.2 9.6 6.6 1.0 2.6 2 1 1 3 3 3 0 Rx N-terminal domain DUF3489 PF11994.8 CDJ89125.1 - 0.046 13.8 0.5 0.11 12.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3489) preATP-grasp_3 PF18301.1 CDJ89125.1 - 0.16 12.3 0.1 0.32 11.3 0.1 1.5 1 0 0 1 1 1 0 pre ATP-grasp 3 domain MutS_V PF00488.21 CDJ89126.1 - 3.1e-53 180.6 0.0 5.3e-53 179.9 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CDJ89126.1 - 2.6e-25 89.8 1.1 2.6e-25 89.8 1.1 2.1 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 CDJ89126.1 - 1.3e-12 48.2 0.1 5.8e-12 46.1 0.1 2.1 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 CDJ89126.1 - 0.00026 21.3 0.3 0.0014 18.9 0.0 2.4 2 0 0 2 2 2 1 MutS family domain IV AAA_14 PF13173.6 CDJ89126.1 - 0.0011 19.0 0.1 0.012 15.6 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CDJ89126.1 - 0.027 14.2 0.0 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CDJ89126.1 - 0.046 13.6 0.0 0.18 11.7 0.0 2.1 1 0 0 1 1 1 0 NACHT domain Pox_A22 PF04848.13 CDJ89126.1 - 0.047 13.8 0.2 0.23 11.6 0.2 2.2 1 1 1 2 2 2 0 Poxvirus A22 protein DUF2459 PF09601.10 CDJ89126.1 - 0.12 12.2 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) CDK5_activator PF03261.15 CDJ89127.1 - 1.2e-06 28.4 0.7 0.00026 20.6 0.1 2.0 1 1 1 2 2 2 2 Cyclin-dependent kinase 5 activator protein HMG_box_2 PF09011.10 CDJ89128.1 - 3.3e-18 66.0 3.8 3.9e-18 65.8 3.8 1.0 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 CDJ89128.1 - 6.5e-13 48.9 3.1 7.8e-13 48.6 3.1 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box COX4 PF02936.14 CDJ89128.1 - 0.011 15.7 0.8 0.024 14.7 0.7 1.5 1 1 1 2 2 2 0 Cytochrome c oxidase subunit IV GPCR_chapero_1 PF11904.8 CDJ89129.1 - 8.4e-85 284.9 0.1 1.4e-84 284.2 0.1 1.3 1 0 0 1 1 1 1 GPCR-chaperone Ank PF00023.30 CDJ89129.1 - 8.3e-07 29.2 0.0 3e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 CDJ89129.1 - 3.1e-06 27.7 0.0 2.5e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ89129.1 - 0.00054 20.5 0.0 0.021 15.4 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ89129.1 - 0.00086 19.6 0.1 0.09 13.4 0.0 3.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 CDJ89129.1 - 0.05 13.9 0.0 0.57 10.6 0.0 2.6 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Lipase_3 PF01764.25 CDJ89130.1 - 5.4e-33 113.8 0.0 8.2e-33 113.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CDJ89130.1 - 0.0022 18.7 0.0 0.0034 18.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2048 PF09752.9 CDJ89130.1 - 0.041 13.0 0.0 0.088 11.9 0.0 1.5 2 0 0 2 2 2 0 Abhydrolase domain containing 18 Abhydrolase_5 PF12695.7 CDJ89130.1 - 0.07 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDJ89130.1 - 0.093 12.4 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.14 CDJ89130.1 - 0.1 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 CDJ89130.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 CDJ89130.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF842 PF05811.13 CDJ89131.1 - 2.8e-44 150.0 10.7 4.4e-44 149.3 10.7 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) VCBS PF13517.6 CDJ89131.1 - 1.8e-14 54.0 17.1 4e-05 24.1 4.5 5.5 4 1 1 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 CDJ89131.1 - 1.1e-13 51.1 12.3 0.0033 17.5 0.0 6.7 7 0 0 7 7 7 4 FG-GAP repeat DUF2627 PF11118.8 CDJ89131.1 - 0.082 13.5 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) DUF3149 PF11346.8 CDJ89131.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) ArsA_ATPase PF02374.15 CDJ89132.1 - 4.3e-135 449.8 0.2 5.1e-100 334.6 0.0 2.1 2 0 0 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.6 CDJ89132.1 - 4.7e-15 56.0 0.0 1.8e-08 34.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain CbiA PF01656.23 CDJ89132.1 - 2.3e-12 47.1 0.0 1.2e-08 35.1 0.0 2.9 2 1 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 CDJ89132.1 - 9.6e-06 25.2 0.1 0.0002 20.9 0.0 2.4 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 CDJ89132.1 - 2e-05 24.2 0.9 0.00022 20.8 0.0 2.4 3 0 0 3 3 3 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 CDJ89132.1 - 0.00015 21.3 0.0 0.0037 16.8 0.0 2.3 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ Zeta_toxin PF06414.12 CDJ89132.1 - 0.0011 18.3 0.0 0.0029 16.9 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin SRP54 PF00448.22 CDJ89132.1 - 0.0018 18.0 0.0 0.019 14.6 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Elf1 PF05129.13 CDJ89132.1 - 0.0019 18.2 1.4 0.0041 17.1 0.0 2.1 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like NB-ARC PF00931.22 CDJ89132.1 - 0.0073 15.5 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_25 PF13481.6 CDJ89132.1 - 0.086 12.4 0.1 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CDJ89132.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Thioredoxin_7 PF13899.6 CDJ89135.1 - 1.9e-14 53.6 0.1 4.5e-14 52.4 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin-like Thioredox_DsbH PF03190.15 CDJ89135.1 - 3.4e-09 36.9 0.2 6.7e-09 35.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 AhpC-TSA PF00578.21 CDJ89135.1 - 0.00014 21.7 0.1 0.00027 20.9 0.1 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 CDJ89135.1 - 0.0013 19.2 0.2 0.0013 19.2 0.2 2.3 1 1 0 2 2 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CDJ89135.1 - 0.0021 18.3 0.2 0.77 10.1 0.1 2.9 1 1 1 2 2 2 2 Thioredoxin-like Paf1 PF03985.13 CDJ89135.1 - 0.024 13.7 30.6 0.036 13.1 30.6 1.3 1 0 0 1 1 1 0 Paf1 SAPS PF04499.15 CDJ89135.1 - 0.35 9.6 12.9 0.34 9.6 12.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 CDJ89135.1 - 0.39 10.5 31.1 0.53 10.1 31.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.12 CDJ89135.1 - 0.57 10.4 17.9 0.67 10.2 17.9 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Hid1 PF12722.7 CDJ89135.1 - 0.68 8.0 11.0 0.66 8.0 11.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDHD PF02862.17 CDJ89135.1 - 1.1 9.3 11.0 2 8.5 11.0 1.5 1 0 0 1 1 1 0 DDHD domain SID-1_RNA_chan PF13965.6 CDJ89135.1 - 4 5.7 6.8 5 5.4 6.8 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SAE2 PF08573.10 CDJ89136.1 - 2.1e-05 25.6 1.0 0.012 16.7 0.0 3.0 2 1 1 3 3 3 2 DNA repair protein endonuclease SAE2/CtIP C-terminus FAM176 PF14851.6 CDJ89136.1 - 0.13 11.9 0.6 0.78 9.4 0.0 2.2 2 0 0 2 2 2 0 FAM176 family S1-like PF14444.6 CDJ89137.1 - 9.3e-32 108.8 0.8 9.3e-32 108.8 0.8 2.5 4 0 0 4 4 4 1 S1-like Sporozoite_P67 PF05642.11 CDJ89137.1 - 0.15 10.2 9.0 0.18 9.9 9.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2457 PF10446.9 CDJ89137.1 - 0.77 8.8 6.7 1 8.4 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FERM_C PF09380.10 CDJ89138.1 - 3.2e-15 56.3 0.0 7.1e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 CDJ89138.1 - 5.7e-15 55.7 0.0 1.5e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 CDJ89138.1 - 8.2e-06 25.7 0.0 4.7e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 FERM N-terminal domain XRCC4 PF06632.12 CDJ89138.1 - 0.023 13.6 2.3 0.036 12.9 2.3 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 I-set PF07679.16 CDJ89139.1 - 2.2e-107 351.3 7.8 2.5e-20 72.3 0.1 7.4 7 0 0 7 7 7 6 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ89139.1 - 4.9e-71 235.3 0.0 1.4e-13 51.2 0.0 7.3 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.25 CDJ89139.1 - 2.3e-31 107.8 8.2 4.5e-06 26.7 0.1 7.4 7 0 0 7 7 6 6 Immunoglobulin domain Ig_2 PF13895.6 CDJ89139.1 - 2.5e-27 95.0 0.0 4.4e-05 23.7 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin domain V-set PF07686.17 CDJ89139.1 - 6.2e-15 55.3 2.8 0.015 15.4 0.1 8.5 6 2 0 6 6 6 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDJ89139.1 - 1.1e-08 35.1 6.1 0.51 10.4 0.0 7.3 8 0 0 8 8 8 3 CD80-like C2-set immunoglobulin domain Spectrin PF00435.21 CDJ89139.1 - 7.1e-05 23.3 1.4 0.00027 21.4 0.3 8.2 8 2 1 9 9 9 3 Spectrin repeat Ig_6 PF18452.1 CDJ89139.1 - 0.00026 20.5 0.0 1.5 8.4 0.0 4.4 5 0 0 5 5 5 1 Immunoglobulin domain Ig_C17orf99 PF17736.1 CDJ89139.1 - 0.035 14.2 0.0 8.4 6.5 0.1 3.5 3 0 0 3 3 3 0 C17orf99 Ig domain Fe_hyd_SSU PF02256.17 CDJ89139.1 - 0.056 13.5 0.3 0.15 12.2 0.3 1.7 1 0 0 1 1 1 0 Iron hydrogenase small subunit Izumo-Ig PF16706.5 CDJ89139.1 - 0.11 12.6 0.2 4 7.6 0.0 3.3 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain RT_RNaseH PF17917.1 CDJ89140.1 - 8.5e-33 112.8 0.0 1.4e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ89140.1 - 1.2e-29 102.3 0.0 2.6e-29 101.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ89140.1 - 2.1e-23 83.0 0.0 3.1e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GEP5 PF17053.5 CDJ89140.1 - 0.029 14.2 0.0 0.25 11.2 0.0 2.0 2 0 0 2 2 2 0 Genetic interactor of prohibitin 5 CAP PF00188.26 CDJ89142.1 - 2.1e-06 28.6 5.9 4.1e-06 27.7 1.8 2.1 1 1 1 2 2 2 2 Cysteine-rich secretory protein family DUF1289 PF06945.13 CDJ89142.1 - 0.029 14.2 2.3 0.057 13.2 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) CAP PF00188.26 CDJ89143.1 - 2.8e-13 50.8 0.1 1e-12 49.0 0.1 1.8 1 1 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ89143.1 - 0.00076 19.7 1.6 0.0017 18.6 1.6 1.6 1 1 0 1 1 1 1 Ancylostoma-associated secreted protein related Nodulin_late PF07127.11 CDJ89143.1 - 2.3 8.6 7.8 0.78 10.1 1.5 2.4 2 0 0 2 2 2 0 Late nodulin protein CAP PF00188.26 CDJ89144.1 - 1e-09 39.3 3.6 1.3e-09 38.9 3.6 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ89144.1 - 0.0086 16.3 0.1 0.012 15.9 0.1 1.2 1 0 0 1 1 1 1 Ancylostoma-associated secreted protein related PDR_CDR PF06422.12 CDJ89148.1 - 0.044 13.7 3.1 2.1 8.3 0.1 3.1 2 1 0 2 2 2 0 CDR ABC transporter Zwilch PF09817.9 CDJ89149.1 - 2.7e-43 148.3 0.0 4.9e-43 147.5 0.0 1.4 1 0 0 1 1 1 1 RZZ complex, subunit zwilch Mis12 PF05859.12 CDJ89149.1 - 0.00023 21.2 0.4 0.0046 17.0 0.4 2.6 1 1 0 1 1 1 1 Mis12 protein V-SNARE PF05008.15 CDJ89149.1 - 0.0039 17.5 2.0 0.067 13.6 0.7 2.8 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus COG5 PF10392.9 CDJ89149.1 - 0.26 11.5 4.6 1.5 9.0 0.6 3.1 3 0 0 3 3 3 0 Golgi transport complex subunit 5 Sec8_exocyst PF04048.14 CDJ89149.1 - 0.45 10.4 3.4 1.2 9.0 1.5 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Myosin_tail_1 PF01576.19 CDJ89150.1 - 1.5e-152 509.9 269.7 1.7e-152 509.6 269.7 1.0 1 0 0 1 1 1 1 Myosin tail Myosin_head PF00063.21 CDJ89150.1 - 2.5e-81 273.9 0.0 3.7e-60 203.9 0.0 4.4 4 1 1 5 5 5 2 Myosin head (motor domain) DUF1664 PF07889.12 CDJ89150.1 - 0.28 11.2 140.7 0.45 10.6 4.2 13.5 3 3 7 13 13 13 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 CDJ89150.1 - 0.71 10.1 259.1 0.024 14.9 33.8 11.4 1 1 7 9 9 9 0 Autophagy protein 16 (ATG16) Glyco_hydro_31 PF01055.26 CDJ89151.1 - 5.5e-73 246.6 3.0 5.5e-73 246.6 3.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Glyco_hydro_31 PF01055.26 CDJ89152.1 - 3.1e-128 428.7 9.2 4.1e-128 428.3 9.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 CDJ89152.1 - 3e-20 72.5 0.0 5.6e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 CDJ89152.1 - 1.4e-09 37.6 2.0 1.4e-09 37.6 2.0 1.8 2 0 0 2 2 2 1 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.6 CDJ89152.1 - 1.7e-06 28.3 0.2 5.9e-06 26.5 0.2 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like HMG_box_2 PF09011.10 CDJ89153.1 - 3.3e-18 66.0 3.8 3.9e-18 65.8 3.8 1.0 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 CDJ89153.1 - 6.5e-13 48.9 3.1 7.8e-13 48.6 3.1 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box COX4 PF02936.14 CDJ89153.1 - 0.011 15.7 0.8 0.024 14.7 0.7 1.5 1 1 1 2 2 2 0 Cytochrome c oxidase subunit IV GPCR_chapero_1 PF11904.8 CDJ89154.1 - 8.4e-85 284.9 0.1 1.4e-84 284.2 0.1 1.3 1 0 0 1 1 1 1 GPCR-chaperone Ank PF00023.30 CDJ89154.1 - 8.3e-07 29.2 0.0 3e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 CDJ89154.1 - 3.1e-06 27.7 0.0 2.5e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ89154.1 - 0.00054 20.5 0.0 0.021 15.4 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ89154.1 - 0.00086 19.6 0.1 0.09 13.4 0.0 3.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 CDJ89154.1 - 0.05 13.9 0.0 0.57 10.6 0.0 2.6 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Lipase_3 PF01764.25 CDJ89155.1 - 5.4e-33 113.8 0.0 8.2e-33 113.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CDJ89155.1 - 0.0022 18.7 0.0 0.0034 18.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2048 PF09752.9 CDJ89155.1 - 0.041 13.0 0.0 0.088 11.9 0.0 1.5 2 0 0 2 2 2 0 Abhydrolase domain containing 18 Abhydrolase_5 PF12695.7 CDJ89155.1 - 0.07 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDJ89155.1 - 0.093 12.4 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.14 CDJ89155.1 - 0.1 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 CDJ89155.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 CDJ89155.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_S10 PF00450.22 CDJ89156.1 - 3.7e-118 395.6 5.7 4.3e-118 395.4 5.7 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 CDJ89159.1 - 2.1e-123 412.9 6.5 2.4e-123 412.7 6.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Arm PF00514.23 CDJ89160.1 - 4.4e-57 188.5 19.5 3.9e-10 39.4 0.1 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 CDJ89160.1 - 3e-14 52.3 0.9 2.8e-13 49.2 0.5 2.4 2 0 0 2 2 2 1 Atypical Arm repeat IBB PF01749.20 CDJ89160.1 - 4.4e-14 52.7 2.4 1.6e-13 50.9 1.8 2.3 2 0 0 2 2 2 1 Importin beta binding domain HEAT_EZ PF13513.6 CDJ89160.1 - 3.7e-13 49.7 12.0 0.00036 20.9 0.6 6.2 4 2 2 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 CDJ89160.1 - 2.6e-12 47.0 5.0 0.018 15.4 1.6 5.8 2 1 5 7 7 7 4 HEAT repeats HEAT PF02985.22 CDJ89160.1 - 1e-08 34.7 8.0 0.04 14.2 0.1 7.8 9 0 0 9 9 8 1 HEAT repeat RICTOR_V PF14668.6 CDJ89160.1 - 0.00019 21.6 2.3 1.1 9.6 0.0 4.6 4 1 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Vac14_Fab1_bd PF12755.7 CDJ89160.1 - 0.0017 18.9 0.0 2.3 8.9 0.0 4.1 3 3 2 5 5 5 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 CDJ89160.1 - 0.0092 15.6 1.3 0.38 10.3 0.0 3.5 2 1 1 4 4 4 1 CLASP N terminal Cnd1 PF12717.7 CDJ89160.1 - 0.011 15.8 4.9 0.29 11.2 0.0 3.7 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 CDJ89160.1 - 0.017 15.2 0.2 5.3 7.2 0.0 3.8 3 1 0 4 4 4 0 V-ATPase subunit H FANCI_S3 PF14677.6 CDJ89160.1 - 0.05 13.3 0.2 0.16 11.7 0.2 1.8 1 0 0 1 1 1 0 FANCI solenoid 3 ParcG PF10274.9 CDJ89160.1 - 0.079 13.1 0.0 0.46 10.6 0.0 2.1 2 0 0 2 2 2 0 Parkin co-regulated protein HEAT_PBS PF03130.16 CDJ89160.1 - 0.14 12.9 4.3 30 5.7 0.2 4.8 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Patched PF02460.18 CDJ89161.1 - 8.6e-27 93.6 12.1 9.7e-27 93.4 12.1 1.0 1 0 0 1 1 1 1 Patched family SecD_SecF PF02355.16 CDJ89161.1 - 0.36 10.2 8.1 0.45 9.9 7.0 1.7 1 1 0 1 1 1 0 Protein export membrane protein DUF1075 PF06388.11 CDJ89162.1 - 3.2e-07 30.4 0.2 4.3e-07 30.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1075) C2 PF00168.30 CDJ89165.1 - 1.7e-17 63.6 0.0 4.5e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 C2 domain PDZ_6 PF17820.1 CDJ89165.1 - 0.00089 19.1 0.1 0.0021 17.9 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CDJ89165.1 - 0.0047 17.2 0.3 0.0098 16.2 0.3 1.5 1 0 0 1 1 1 1 PDZ domain SHE3 PF17078.5 CDJ89165.1 - 0.022 14.5 4.0 0.054 13.2 4.0 1.6 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Metal_resist PF13801.6 CDJ89165.1 - 1.5 9.0 11.5 21 5.3 0.5 4.3 3 1 1 4 4 4 0 Heavy-metal resistance Lip_prot_lig_C PF10437.9 CDJ89166.1 - 0.15 12.1 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus PA28_beta PF02252.18 CDJ89168.1 - 2.7e-54 182.8 0.3 3e-54 182.6 0.3 1.0 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit Choline_kinase PF01633.20 CDJ89169.1 - 9.9e-40 136.4 0.0 2.4e-24 86.1 0.0 2.2 1 1 1 2 2 2 2 Choline/ethanolamine kinase APH PF01636.23 CDJ89169.1 - 1.3e-06 28.5 0.0 0.0074 16.2 0.0 3.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.20 CDJ89169.1 - 0.059 12.7 0.0 0.9 8.8 0.0 2.2 1 1 0 1 1 1 0 Ecdysteroid kinase Optomotor-blind PF11078.8 CDJ89169.1 - 0.21 12.1 0.0 0.43 11.2 0.0 1.4 1 0 0 1 1 1 0 Optomotor-blind protein N-terminal region UDPGT PF00201.18 CDJ89170.1 - 1.6e-43 149.3 0.0 2.9e-43 148.4 0.0 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ89170.1 - 1.9e-10 41.0 0.0 3.7e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain VirB8 PF04335.13 CDJ89172.1 - 0.064 13.1 0.0 0.085 12.7 0.0 1.1 1 0 0 1 1 1 0 VirB8 protein Gram_pos_anchor PF00746.21 CDJ89172.1 - 0.24 11.4 0.2 0.49 10.4 0.1 1.5 2 0 0 2 2 2 0 LPXTG cell wall anchor motif TMEM52 PF14979.6 CDJ89172.1 - 1.3 8.9 5.1 7.3 6.5 0.1 2.3 1 1 1 2 2 2 0 Transmembrane 52 Collagen PF01391.18 CDJ89173.1 - 2.8e-21 75.0 113.8 5.8e-09 35.6 42.2 3.7 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ89173.1 - 3.3e-19 68.7 0.4 4.1e-19 68.4 0.4 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain IBV_3B PF03622.13 CDJ89173.1 - 0.11 12.7 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 IBV 3B protein FeoB_associated PF12669.7 CDJ89173.1 - 8.8 6.8 9.2 6.1 7.3 2.3 2.5 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Collagen PF01391.18 CDJ89174.1 - 5.4e-20 70.9 120.1 2.4e-09 36.8 41.8 3.7 2 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ89174.1 - 4.7e-09 36.2 1.6 5.8e-09 35.9 1.6 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain IBV_3B PF03622.13 CDJ89174.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 IBV 3B protein FeoB_associated PF12669.7 CDJ89174.1 - 7.1 7.1 9.4 3.9 7.9 2.8 2.3 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Collagen PF01391.18 CDJ89175.1 - 2.5e-14 52.8 64.8 2.3e-05 24.1 9.0 3.3 3 0 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ89175.1 - 4.7e-09 36.2 1.6 5.8e-09 35.9 1.6 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain IBV_3B PF03622.13 CDJ89175.1 - 0.11 12.6 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 IBV 3B protein Collagen PF01391.18 CDJ89176.1 - 2.5e-30 104.0 147.8 2.9e-10 39.7 38.2 4.6 4 1 0 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ89176.1 - 2e-19 69.3 0.3 2.5e-19 69.1 0.3 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Lectin_C PF00059.21 CDJ89177.1 - 1.5e-16 61.0 0.8 2e-16 60.7 0.8 1.1 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 CDJ89177.1 - 0.0062 16.2 0.0 0.0079 15.9 0.0 1.2 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like 7tm_1 PF00001.21 CDJ89178.1 - 0.004 16.5 12.9 0.18 11.1 6.1 3.1 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) Mitoc_L55 PF09776.9 CDJ89178.1 - 0.019 14.7 1.8 0.026 14.3 0.5 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L55 Motile_Sperm PF00635.26 CDJ89179.1 - 2.1e-18 66.2 0.0 2.7e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain zf-A20 PF01754.16 CDJ89180.1 - 7e-12 45.1 8.2 7e-12 45.1 8.2 2.3 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.16 CDJ89180.1 - 3.5e-10 39.9 7.9 3.5e-10 39.9 7.9 2.1 2 0 0 2 2 2 1 AN1-like Zinc finger zf-C5HC2 PF02928.16 CDJ89180.1 - 0.039 14.3 3.7 0.039 14.3 3.7 2.1 2 0 0 2 2 2 0 C5HC2 zinc finger Metalloenzyme PF01676.18 CDJ89181.1 - 1.4e-81 273.6 0.0 1.6e-81 273.4 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 CDJ89181.1 - 9.4e-75 250.8 0.0 1.7e-74 249.9 0.0 1.4 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.22 CDJ89181.1 - 2.1e-06 27.6 0.0 3.4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Alk_phosphatase PF00245.20 CDJ89181.1 - 0.0073 15.3 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Alkaline phosphatase PglZ PF08665.12 CDJ89181.1 - 0.14 12.3 0.0 0.61 10.2 0.0 1.9 2 0 0 2 2 2 0 PglZ domain Rad60-SLD PF11976.8 CDJ89182.1 - 0.0002 21.1 0.0 0.0032 17.3 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CDJ89182.1 - 0.0014 18.3 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Radial_spoke_3 PF06098.11 CDJ89182.1 - 0.036 13.4 0.1 0.052 12.8 0.1 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 Homeodomain PF00046.29 CDJ89182.1 - 0.25 11.2 1.8 3.8 7.4 0.8 2.3 2 0 0 2 2 2 0 Homeodomain bZIP_1 PF00170.21 CDJ89183.1 - 1.6e-14 53.8 12.2 3e-14 52.9 12.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CDJ89183.1 - 1.1e-08 35.0 12.5 2.3e-08 34.0 12.5 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CDJ89183.1 - 7.2e-08 32.8 10.0 7.2e-08 32.8 10.0 2.1 2 0 0 2 2 2 1 bZIP Maf transcription factor Spc7 PF08317.11 CDJ89183.1 - 0.018 14.0 6.7 0.031 13.2 6.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein RmuC PF02646.16 CDJ89183.1 - 0.018 14.2 2.2 0.03 13.4 2.2 1.3 1 0 0 1 1 1 0 RmuC family DivIC PF04977.15 CDJ89183.1 - 0.053 13.3 6.3 0.13 12.0 6.3 1.7 1 0 0 1 1 1 0 Septum formation initiator TolA_bind_tri PF16331.5 CDJ89183.1 - 0.083 13.0 8.5 0.29 11.2 8.5 2.0 1 0 0 1 1 1 0 TolA binding protein trimerisation Macoilin PF09726.9 CDJ89183.1 - 0.14 10.7 4.7 0.21 10.1 4.7 1.2 1 0 0 1 1 1 0 Macoilin family ParE_toxin PF05016.15 CDJ89183.1 - 0.31 11.7 2.0 0.72 10.5 2.0 1.7 1 1 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE UPF0242 PF06785.11 CDJ89183.1 - 0.34 11.0 6.6 0.64 10.1 6.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 CDJ89183.1 - 1.2 8.9 6.6 6.6 6.5 4.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) ZapB PF06005.12 CDJ89183.1 - 1.7 9.1 9.2 0.45 11.0 5.1 2.0 1 1 1 2 2 2 0 Cell division protein ZapB DUF2650 PF10853.8 CDJ89184.1 - 8.1e-16 57.4 5.8 1.3e-15 56.8 5.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2650) DUF2798 PF11391.8 CDJ89184.1 - 0.13 12.3 3.2 0.49 10.5 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) PCI PF01399.27 CDJ89185.1 - 2.3e-20 73.1 0.5 9.7e-20 71.1 0.5 2.1 1 0 0 1 1 1 1 PCI domain RPN6_N PF18055.1 CDJ89185.1 - 1.1e-18 67.7 1.7 3.5e-18 66.1 0.2 2.5 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain RPN6_C_helix PF18503.1 CDJ89185.1 - 4.8e-09 35.8 0.3 9.6e-09 34.8 0.3 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain PLD_C PF12357.8 CDJ89185.1 - 0.0079 16.1 0.0 0.024 14.5 0.0 1.9 1 1 1 2 2 2 1 Phospholipase D C terminal TPALS PF18178.1 CDJ89186.1 - 0.039 13.4 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family Ribosomal_S19 PF00203.21 CDJ89187.1 - 9.3e-33 112.0 0.1 1.3e-32 111.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 B12D PF06522.11 CDJ89188.1 - 0.00063 19.5 0.1 0.001 18.8 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit PIG-Y PF15159.6 CDJ89188.1 - 0.022 15.7 1.0 0.038 14.9 1.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Holin_BhlA PF10960.8 CDJ89188.1 - 0.17 11.9 0.1 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 BhlA holin family Muted PF14942.6 CDJ89189.1 - 0.82 10.0 6.0 0.49 10.7 3.8 1.7 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Syja_N PF02383.18 CDJ89190.1 - 1e-75 255.0 0.2 2.1e-74 250.7 0.0 2.2 2 0 0 2 2 2 1 SacI homology domain DUF5492 PF17596.2 CDJ89190.1 - 0.027 14.8 0.0 0.057 13.7 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5492) WYL PF13280.6 CDJ89190.1 - 0.067 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 WYL domain GTP_cyclohydro2 PF00925.20 CDJ89191.1 - 0.022 14.4 0.3 0.046 13.3 0.3 1.5 1 0 0 1 1 1 0 GTP cyclohydrolase II DHR10 PF18595.1 CDJ89191.1 - 1.1 9.3 8.5 1.8 8.6 0.0 2.5 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain LIM PF00412.22 CDJ89192.1 - 2e-23 82.4 21.2 2e-12 47.1 5.5 2.5 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 CDJ89192.1 - 1.1e-13 50.8 0.5 1.8e-13 50.1 0.5 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ89192.1 - 0.016 15.1 0.1 0.044 13.7 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain IFT57 PF10498.9 CDJ89193.1 - 3.9e-118 394.6 7.0 4.9e-118 394.2 7.0 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DASH_Spc19 PF08287.11 CDJ89193.1 - 1.2e-05 25.3 5.4 1.2e-05 25.3 5.4 2.6 3 1 1 4 4 4 1 Spc19 Taxilin PF09728.9 CDJ89193.1 - 0.016 14.4 7.7 0.031 13.5 7.7 1.4 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Sigma70_r3 PF04539.16 CDJ89193.1 - 0.026 14.6 1.5 0.026 14.6 1.5 2.5 3 0 0 3 3 2 0 Sigma-70 region 3 Spc7 PF08317.11 CDJ89193.1 - 0.037 12.9 9.7 0.063 12.1 9.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein KxDL PF10241.9 CDJ89193.1 - 0.042 14.1 1.9 1.1 9.6 0.7 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein Chibby PF14645.6 CDJ89193.1 - 0.15 12.5 2.4 1.5 9.3 2.4 2.3 1 1 0 1 1 1 0 Chibby family DUF1664 PF07889.12 CDJ89193.1 - 0.22 11.6 9.6 1.6 8.8 3.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) HAUS6_N PF14661.6 CDJ89193.1 - 0.23 11.0 6.4 1 8.9 6.3 2.1 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF5082 PF16888.5 CDJ89193.1 - 0.24 11.7 11.7 2.2 8.6 0.6 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) Holin_BhlA PF10960.8 CDJ89193.1 - 0.27 11.2 3.9 2.7 8.0 0.0 3.6 4 0 0 4 4 4 0 BhlA holin family Phage_Mu_Gam PF07352.12 CDJ89193.1 - 0.4 10.6 7.3 0.29 11.0 2.9 2.3 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein Fib_alpha PF08702.10 CDJ89193.1 - 0.46 10.7 5.5 1.3 9.2 5.2 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 CDJ89193.1 - 0.86 9.6 4.2 1.2 9.1 0.1 2.3 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GCIP PF13324.6 CDJ89193.1 - 0.95 9.0 8.9 0.29 10.7 5.7 1.8 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting DUF4164 PF13747.6 CDJ89193.1 - 0.96 9.8 8.5 0.53 10.6 1.6 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Laminin_II PF06009.12 CDJ89193.1 - 1.4 9.0 7.5 2.8 7.9 2.8 2.7 1 1 2 3 3 3 0 Laminin Domain II CorA PF01544.18 CDJ89193.1 - 1.4 8.2 6.9 1.3 8.3 5.3 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF948 PF06103.11 CDJ89193.1 - 2.5 8.4 6.2 12 6.2 0.2 3.0 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF16 PF01519.16 CDJ89193.1 - 4.1 8.0 11.7 18 5.9 3.4 3.0 1 1 2 3 3 3 0 Protein of unknown function DUF16 DUF724 PF05266.14 CDJ89193.1 - 4.9 6.9 10.6 0.67 9.8 3.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DNA_repr_REX1B PF14966.6 CDJ89193.1 - 6.2 7.6 7.0 4 8.2 0.3 3.2 1 1 1 3 3 3 0 DNA repair REX1-B DSPc PF00782.20 CDJ89194.1 - 6e-36 123.2 0.0 7.6e-36 122.9 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDJ89194.1 - 0.012 15.2 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase cPLA2_C2 PF18695.1 CDJ89195.1 - 0.017 15.1 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Cytosolic phospholipases A2 C2-domain DB PF01682.19 CDJ89196.1 - 7e-17 61.6 12.5 8.5e-17 61.3 12.5 1.1 1 0 0 1 1 1 1 DB module Neur_chan_memb PF02932.16 CDJ89199.1 - 4.8e-14 53.0 0.0 5.4e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region LapA_dom PF06305.11 CDJ89199.1 - 0.31 10.9 1.3 0.42 10.4 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Neur_chan_LBD PF02931.23 CDJ89200.1 - 3.6e-37 127.9 6.7 8.8e-20 71.1 3.8 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ89200.1 - 7.9e-36 124.3 10.4 1.1e-35 123.9 10.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.10 CDJ89200.1 - 0.88 8.2 6.0 1.1 7.8 6.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Tetraspanin PF00335.20 CDJ89200.1 - 0.99 9.1 4.9 3.2 7.4 0.9 2.1 2 0 0 2 2 2 0 Tetraspanin family DUF3043 PF11241.8 CDJ89200.1 - 8.4 6.4 7.4 2.5 8.1 4.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) Orf78 PF06024.12 CDJ89201.1 - 0.017 15.5 0.9 0.023 15.0 0.2 1.6 1 1 1 2 2 2 0 Orf78 (ac78) DUF3139 PF11337.8 CDJ89201.1 - 0.028 15.0 0.3 0.035 14.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) DUF2681 PF10883.8 CDJ89201.1 - 0.039 14.3 3.0 0.051 14.0 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Sigma_reg_N PF13800.6 CDJ89201.1 - 0.066 13.5 0.1 0.092 13.0 0.1 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal ATG101 PF07855.12 CDJ89201.1 - 0.12 12.3 2.1 0.14 12.2 2.1 1.2 1 1 0 1 1 1 0 Autophagy-related protein 101 SieB PF14163.6 CDJ89201.1 - 0.32 10.5 3.2 0.54 9.7 3.2 1.5 1 1 0 1 1 1 0 Super-infection exclusion protein B UPF0542 PF15086.6 CDJ89201.1 - 0.39 10.7 7.9 1.8 8.6 0.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0542 LIM PF00412.22 CDJ89202.1 - 2.2e-35 120.7 36.6 2.9e-14 53.0 6.5 3.3 3 0 0 3 3 3 3 LIM domain zf-RRN7 PF11781.8 CDJ89202.1 - 0.0026 17.4 2.1 0.0026 17.4 2.1 3.2 3 0 0 3 3 3 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 LptE PF04390.12 CDJ89202.1 - 0.09 13.5 0.1 0.21 12.3 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide-assembly RGM_C PF06534.13 CDJ89203.1 - 2.1e-39 134.8 0.3 4e-39 133.9 0.1 1.6 2 0 0 2 2 2 1 Repulsive guidance molecule (RGM) C-terminus RGM_N PF06535.12 CDJ89203.1 - 7.8e-32 110.7 2.6 1.5e-31 109.9 2.6 1.5 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) N-terminus Totivirus_coat PF05518.11 CDJ89204.1 - 9.6 4.1 10.4 12 3.8 10.4 1.0 1 0 0 1 1 1 0 Totivirus coat protein Ldl_recept_a PF00057.18 CDJ89206.1 - 4e-173 561.3 383.5 9.3e-12 45.0 16.3 22.9 21 1 0 22 22 22 21 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 CDJ89206.1 - 1.5e-33 115.0 2.6 4e-08 33.6 0.0 7.8 7 0 0 7 7 7 7 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 CDJ89206.1 - 7e-16 58.2 57.4 8.4e-10 38.8 10.3 13.4 12 1 0 12 12 12 6 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 CDJ89206.1 - 4.7e-09 36.3 24.9 3.6e-07 30.3 6.0 24.0 17 7 8 26 26 26 3 Calcium-binding EGF domain cEGF PF12662.7 CDJ89206.1 - 2.4e-05 24.1 5.1 2.4e-05 24.1 5.1 10.7 11 0 0 11 11 11 4 Complement Clr-like EGF-like MH2 PF03166.14 CDJ89207.1 - 5.7e-16 59.3 0.0 4.7e-15 56.3 0.0 2.0 1 1 0 1 1 1 1 MH2 domain MH1 PF03165.16 CDJ89207.1 - 1e-09 38.5 0.2 2.4e-09 37.3 0.1 1.7 1 1 0 1 1 1 1 MH1 domain dsrm PF00035.26 CDJ89208.1 - 1.9e-06 28.5 0.1 0.00011 22.8 0.0 3.3 3 1 0 3 3 3 1 Double-stranded RNA binding motif Par3_HAL_N_term PF12053.8 CDJ89208.1 - 0.035 14.3 6.2 0.32 11.3 0.1 3.3 2 0 0 2 2 2 0 N-terminal of Par3 and HAL proteins COS PF18568.1 CDJ89208.1 - 0.098 12.6 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 TRIM C-terminal subgroup One Signature domain TF_AP-2 PF03299.14 CDJ89209.1 - 4.8e-44 150.7 0.1 6.9e-44 150.2 0.1 1.2 1 0 0 1 1 1 1 Transcription factor AP-2 Y_phosphatase PF00102.27 CDJ89210.1 - 2.6e-68 230.1 0.1 4.8e-68 229.2 0.0 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ89210.1 - 9.5e-06 25.5 0.0 2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDJ89210.1 - 6.1e-05 23.1 0.0 0.00019 21.5 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CDJ89210.1 - 0.00015 21.9 0.3 0.00055 20.1 0.0 2.1 2 0 0 2 2 2 1 Inositol hexakisphosphate Myotub-related PF06602.14 CDJ89210.1 - 0.015 14.2 0.3 0.075 11.9 0.0 2.0 2 0 0 2 2 2 0 Myotubularin-like phosphatase domain ALMS_motif PF15309.6 CDJ89210.1 - 0.064 13.7 0.2 0.064 13.7 0.2 2.4 1 1 1 2 2 2 0 ALMS motif Mitofilin PF09731.9 CDJ89210.1 - 8.5 5.1 12.8 11 4.7 12.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TF_AP-2 PF03299.14 CDJ89212.1 - 2.5e-46 158.1 0.3 5e-46 157.2 0.3 1.5 1 1 0 1 1 1 1 Transcription factor AP-2 Med13_C PF06333.12 CDJ89212.1 - 0.044 13.0 0.6 0.067 12.5 0.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain 7TM_GPCR_Srab PF10292.9 CDJ89213.1 - 2.8e-16 59.4 3.9 3.2e-16 59.1 3.9 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Sra PF02117.16 CDJ89213.1 - 1.1e-06 27.8 1.0 1.2e-06 27.6 1.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sra 7TM_GPCR_Srb PF02175.16 CDJ89213.1 - 0.0018 18.1 0.5 0.0026 17.6 0.2 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srb DUF4064 PF13273.6 CDJ89213.1 - 0.002 18.4 0.9 0.0028 17.9 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) DUF1240 PF06836.12 CDJ89213.1 - 0.0091 16.5 3.2 1.4 9.5 0.6 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF1240) DUF898 PF05987.13 CDJ89213.1 - 0.053 12.6 1.0 0.057 12.5 1.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Stevor PF17410.2 CDJ89213.1 - 0.29 10.6 3.0 0.12 11.9 0.7 1.5 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Neur_chan_LBD PF02931.23 CDJ89214.1 - 2.3e-21 76.2 0.1 3.9e-21 75.5 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Zona_pellucida PF00100.23 CDJ89214.1 - 9.2e-16 58.4 0.5 1.4e-15 57.8 0.5 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain eIF3_N PF09440.10 CDJ89215.1 - 2.1e-34 118.8 2.7 2.1e-34 118.8 2.7 2.5 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 CDJ89215.1 - 1.8e-19 70.2 0.2 8.5e-19 68.0 0.2 2.3 1 0 0 1 1 1 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 CDJ89215.1 - 0.054 13.5 0.1 0.27 11.2 0.1 2.2 1 1 1 2 2 2 0 CSN8/PSMD8/EIF3K family Metallophos PF00149.28 CDJ89217.1 - 0.025 15.1 0.0 0.037 14.5 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase CAS_C PF12026.8 CDJ89218.1 - 2.4e-38 132.4 0.1 6.7e-38 130.9 0.0 1.8 2 0 0 2 2 2 1 Crk-Associated Substrate C-terminal domain Serine_rich PF08824.10 CDJ89218.1 - 5.4e-13 49.2 1.1 1.4e-12 47.9 0.3 2.0 2 0 0 2 2 2 1 Serine rich protein interaction domain 7TM_GPCR_Srt PF10321.9 CDJ89219.1 - 6.9e-23 81.1 9.9 8.6e-23 80.8 6.0 1.9 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srt Zona_pellucida PF00100.23 CDJ89220.1 - 6.9e-13 49.0 7.7 8.3e-13 48.7 7.7 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain HEAT_2 PF13646.6 CDJ89221.1 - 6.2e-06 26.5 0.6 0.0022 18.4 0.1 3.4 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 CDJ89221.1 - 1.2e-05 25.2 2.7 0.044 14.0 0.0 4.2 4 1 1 5 5 5 2 HEAT repeat Cnd1 PF12717.7 CDJ89221.1 - 0.0081 16.2 0.1 19 5.2 0.0 3.5 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CDJ89221.1 - 0.065 13.8 2.0 1.1 9.9 0.2 3.9 4 1 0 4 4 4 0 HEAT-like repeat GSHPx PF00255.19 CDJ89222.1 - 8.9e-38 128.2 2.1 1.2e-37 127.7 2.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CDJ89222.1 - 8.2e-11 41.9 0.4 1.8e-07 31.1 0.1 2.1 1 1 1 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 CDJ89222.1 - 3.9e-07 29.9 0.5 2.1e-06 27.5 0.5 1.9 1 1 0 1 1 1 1 Redoxin Nucleotid_trans PF03407.16 CDJ89224.1 - 4.3e-25 88.9 0.1 5.9e-25 88.5 0.1 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase SH3_15 PF18346.1 CDJ89225.1 - 0.072 13.4 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Mind bomb SH3 repeat domain HCO3_cotransp PF00955.21 CDJ89226.1 - 7.5e-152 506.7 17.0 1.6e-149 499.0 17.0 2.1 1 1 0 1 1 1 1 HCO3- transporter family PTS_EIIA_2 PF00359.22 CDJ89226.1 - 0.00032 20.6 0.0 0.00074 19.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Band_3_cyto PF07565.13 CDJ89226.1 - 0.0005 20.0 2.1 0.28 11.0 0.1 2.3 2 0 0 2 2 2 2 Band 3 cytoplasmic domain Ion_trans_2 PF07885.16 CDJ89228.1 - 4.4e-25 87.5 30.4 7.2e-14 51.5 10.7 2.8 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CDJ89228.1 - 0.00033 20.0 10.8 0.0058 15.9 4.3 2.6 2 0 0 2 2 2 2 Ion transport protein Lig_chan PF00060.26 CDJ89228.1 - 2.8 7.8 8.7 0.45 10.3 1.8 2.8 2 2 0 2 2 2 0 Ligand-gated ion channel CENP-B_dimeris PF09026.10 CDJ89228.1 - 3 8.3 9.1 3 8.3 7.8 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Importin_rep_4 PF18808.1 CDJ89228.1 - 4.9 7.5 7.2 13 6.2 7.2 1.6 1 0 0 1 1 1 0 Importin repeat UPF0139 PF03669.13 CDJ89228.1 - 8.3 6.4 6.4 5.3 7.0 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0139) CBFD_NFYB_HMF PF00808.23 CDJ89229.1 - 3.7e-16 59.2 2.0 5.5e-16 58.6 2.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDJ89229.1 - 1.2e-05 25.7 0.5 1.2e-05 25.7 0.5 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Exo_endo_phos_2 PF14529.6 CDJ89230.1 - 0.0042 16.9 0.0 0.0078 16.1 0.0 1.5 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ89230.1 - 0.056 12.9 0.0 0.14 11.7 0.0 1.6 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Peptidase_A17 PF05380.13 CDJ89232.1 - 1.5e-37 129.1 0.7 2.7e-37 128.3 0.7 1.5 1 0 0 1 1 1 1 Pao retrotransposon peptidase Integrase_H2C2 PF17921.1 CDJ89232.1 - 3.5e-28 97.5 16.9 2.1e-14 53.3 1.1 4.3 4 0 0 4 4 4 2 Integrase zinc binding domain rve PF00665.26 CDJ89232.1 - 4e-19 69.0 0.0 4.8e-10 39.7 0.0 2.5 2 0 0 2 2 2 2 Integrase core domain RVT_1 PF00078.27 CDJ89232.1 - 4.1e-08 33.0 0.0 9.8e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 CDJ89232.1 - 0.00024 20.8 0.1 0.0038 17.0 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 CDJ89232.1 - 0.00039 20.6 16.3 0.083 13.1 4.2 2.8 2 0 0 2 2 2 2 H2C2 zinc finger DUF2583 PF10762.9 CDJ89232.1 - 0.011 16.2 0.2 11 6.5 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) RecR PF02132.15 CDJ89232.1 - 2.3 7.9 10.1 5.6 6.6 0.7 3.1 3 0 0 3 3 3 0 RecR protein DUF2451 PF10474.9 CDJ89233.1 - 2.1e-81 273.2 0.8 3.5e-81 272.4 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 CDJ89233.1 - 5.9e-74 249.0 11.1 1.1e-73 248.1 11.1 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Dor1 PF04124.12 CDJ89233.1 - 0.0043 15.8 2.5 0.023 13.4 1.6 2.3 2 0 0 2 2 2 1 Dor1-like family MMS22L_C PF14911.6 CDJ89233.1 - 0.0063 15.6 0.4 0.012 14.8 0.4 1.4 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, C-terminal Imm6 PF14434.6 CDJ89233.1 - 0.0086 16.0 0.3 0.076 13.0 0.1 2.6 2 0 0 2 2 2 1 Immunity protein Imm6 DUF2408 PF10303.9 CDJ89233.1 - 0.026 15.1 5.3 0.93 10.1 2.7 3.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) GMP_PDE_delta PF05351.11 CDJ89234.1 - 8.1e-73 243.7 2.6 1e-72 243.4 2.6 1.1 1 0 0 1 1 1 1 GMP-PDE, delta subunit PHD PF00628.29 CDJ89235.1 - 1.7e-17 63.0 22.2 6.7e-11 41.9 7.3 2.5 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.6 CDJ89235.1 - 5e-05 23.5 11.5 0.023 14.9 0.1 3.1 2 1 1 3 3 3 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CDJ89235.1 - 0.00033 20.8 6.3 0.24 11.6 0.8 2.6 2 0 0 2 2 2 2 PHD-zinc-finger like domain Zf_RING PF16744.5 CDJ89235.1 - 0.0021 18.1 2.2 0.0021 18.1 2.2 3.0 3 0 0 3 3 3 1 KIAA1045 RING finger C1_1 PF00130.22 CDJ89235.1 - 0.0025 17.7 0.8 0.0025 17.7 0.8 3.2 4 0 0 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 CDJ89235.1 - 0.32 10.6 15.9 2.2 7.9 5.6 3.0 2 1 0 2 2 2 0 PHD-finger Anti-TRAP PF15777.5 CDJ89235.1 - 0.87 9.6 4.3 13 5.8 1.0 2.7 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein C1_2 PF03107.16 CDJ89235.1 - 2 8.8 14.9 0.52 10.7 0.7 3.6 3 0 0 3 3 3 0 C1 domain Peptidase_M8 PF01457.16 CDJ89236.1 - 1e-67 229.0 3.7 3.4e-67 227.3 3.7 1.7 1 1 0 1 1 1 1 Leishmanolysin Myosin_head PF00063.21 CDJ89237.1 - 4e-22 78.2 0.1 5.3e-22 77.8 0.1 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 CDJ89237.1 - 6.2e-13 48.3 2.5 8.7e-13 47.9 2.5 1.2 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain zf-NOSIP PF15906.5 CDJ89238.1 - 2.7e-36 123.6 0.2 4.8e-36 122.8 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 CDJ89238.1 - 2.6e-08 33.6 7.9 0.00075 18.9 0.1 3.1 2 2 1 3 3 3 2 Rtf2 RING-finger U-box PF04564.15 CDJ89238.1 - 8.7e-06 25.8 0.0 0.0008 19.5 0.0 2.5 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.8 CDJ89238.1 - 0.00054 19.7 0.3 0.0052 16.6 0.0 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit HECW_N PF16562.5 CDJ89238.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 MRP-S24 PF14955.6 CDJ89238.1 - 0.13 12.2 0.5 0.36 10.8 0.1 1.8 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S24 ARS2 PF04959.13 CDJ89238.1 - 0.15 12.4 6.0 3.2 8.1 0.1 2.5 2 1 0 2 2 2 0 Arsenite-resistance protein 2 HECT PF00632.25 CDJ89240.1 - 3.3e-90 302.7 0.0 4.3e-90 302.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECW1_helix PF18436.1 CDJ89240.1 - 3e-24 84.9 0.1 6.1e-24 83.9 0.1 1.5 1 0 0 1 1 1 1 Helical box domain of E3 ubiquitin-protein ligase HECW1 WW PF00397.26 CDJ89240.1 - 8.1e-13 48.2 0.0 3.2e-12 46.3 0.3 1.9 2 0 0 2 2 2 1 WW domain ART PF01129.18 CDJ89240.1 - 0.026 13.8 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase SR-25 PF10500.9 CDJ89240.1 - 0.62 9.6 5.5 0.94 9.0 5.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HECT PF00632.25 CDJ89241.1 - 0.0063 16.0 0.0 0.0085 15.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PA26 PF04636.13 CDJ89242.1 - 0.057 12.3 2.0 0.072 12.0 2.0 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Pkinase_Tyr PF07714.17 CDJ89243.1 - 2.2e-85 286.1 0.0 3.2e-85 285.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.24 CDJ89243.1 - 4.5e-47 158.8 1.7 6.5e-25 87.4 0.6 2.5 2 0 0 2 2 2 2 Receptor L domain Pkinase PF00069.25 CDJ89243.1 - 6.3e-44 150.3 0.0 9.7e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.20 CDJ89243.1 - 2.1e-23 82.8 34.3 6.1e-23 81.4 34.3 1.8 1 0 0 1 1 1 1 Furin-like cysteine rich region fn3 PF00041.21 CDJ89243.1 - 5.1e-22 78.0 11.4 1.9e-05 24.9 0.0 6.7 5 1 1 6 6 6 5 Fibronectin type III domain APH PF01636.23 CDJ89243.1 - 0.0093 15.9 0.2 0.021 14.8 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDJ89243.1 - 0.058 13.0 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Sigma_reg_N PF13800.6 CDJ89243.1 - 0.063 13.6 0.0 0.45 10.8 0.1 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Hydantoinase_A PF01968.18 CDJ89244.1 - 3.5e-82 276.0 0.1 1.8e-81 273.6 0.0 2.0 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 CDJ89244.1 - 5.6e-63 211.9 0.6 1.1e-60 204.4 0.0 2.2 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region RRM_1 PF00076.22 CDJ89245.1 - 1.1e-06 28.4 0.0 0.0047 16.7 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Apt1 PF10351.9 CDJ89245.1 - 3.1 6.6 7.7 4.9 5.9 7.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 CDJ89245.1 - 3.6 5.7 10.3 5.6 5.1 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Sugar_tr PF00083.24 CDJ89246.1 - 6.7e-121 404.3 30.3 8.3e-121 404.0 30.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ89246.1 - 1.1e-17 64.0 36.8 1.1e-17 64.0 36.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily SBF2 PF12335.8 CDJ89247.1 - 6.1e-32 111.1 0.4 7.8e-32 110.7 0.4 1.0 1 0 0 1 1 1 1 Myotubularin protein 7tm_7 PF08395.12 CDJ89249.1 - 0.0095 15.2 0.7 0.013 14.7 0.7 1.1 1 0 0 1 1 1 1 7tm Chemosensory receptor Comm PF15957.5 CDJ89249.1 - 0.064 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Commissureless Neur_chan_memb PF02932.16 CDJ89249.1 - 0.065 13.3 3.4 0.24 11.4 3.4 2.0 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region WBP-1 PF11669.8 CDJ89249.1 - 0.073 13.7 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 WW domain-binding protein 1 Tetraspanin PF00335.20 CDJ89249.1 - 0.089 12.5 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Tetraspanin family LapA_dom PF06305.11 CDJ89249.1 - 0.18 11.7 1.4 0.27 11.1 0.2 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Comm PF15957.5 CDJ89250.1 - 0.037 14.4 0.3 0.07 13.5 0.3 1.4 1 0 0 1 1 1 0 Commissureless WBP-1 PF11669.8 CDJ89250.1 - 0.042 14.5 0.9 0.042 14.5 0.9 1.9 2 0 0 2 2 2 0 WW domain-binding protein 1 Foamy_virus_ENV PF03408.14 CDJ89250.1 - 1.7 6.4 3.3 2.3 5.9 3.3 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein Topoisom_bac PF01131.20 CDJ89252.1 - 1.5e-116 389.8 0.0 1.8e-116 389.6 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CDJ89252.1 - 8.8e-16 58.0 0.0 1.6e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Toprim domain HypA PF01155.19 CDJ89252.1 - 0.3 11.1 4.0 3.6 7.6 0.1 3.0 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PAS_11 PF14598.6 CDJ89253.1 - 3.7e-10 39.9 0.0 7.2e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 PAS domain RabGAP-TBC PF00566.18 CDJ89254.1 - 9.3e-34 117.0 6.9 1.2e-33 116.6 2.5 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 CDJ89254.1 - 1.3e-32 112.6 0.0 2.1e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Rab-binding domain (RBD) RUN PF02759.19 CDJ89254.1 - 2.4e-18 66.4 0.2 4.7e-18 65.5 0.2 1.5 1 0 0 1 1 1 1 RUN domain Transcrip_reg PF01709.20 CDJ89255.1 - 1.6e-50 171.8 0.1 1.8e-50 171.6 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator DEAD_2 PF06733.15 CDJ89256.1 - 1e-45 155.5 1.5 1.8e-45 154.7 1.5 1.4 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 CDJ89256.1 - 2.1e-39 135.2 1.9 1.4e-34 119.4 0.4 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 CDJ89256.1 - 7.2e-39 133.7 4.1 2.5e-32 112.4 0.1 3.0 2 1 1 3 3 3 2 Helicase C-terminal domain ResIII PF04851.15 CDJ89256.1 - 7.1e-06 26.1 0.0 0.024 14.6 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ89256.1 - 0.00085 19.1 0.0 1.7 8.4 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase SNF2_N PF00176.23 CDJ89256.1 - 0.0083 14.9 0.0 0.043 12.5 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Cast PF10174.9 CDJ89256.1 - 0.012 13.9 0.6 0.017 13.4 0.6 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone AAA_22 PF13401.6 CDJ89256.1 - 0.15 12.4 0.7 57 4.0 0.0 3.5 3 1 0 3 3 3 0 AAA domain BTB PF00651.31 CDJ89257.1 - 1.3e-21 76.9 0.3 2.7e-21 75.9 0.1 1.6 2 0 0 2 2 2 1 BTB/POZ domain MATH PF00917.26 CDJ89257.1 - 7.3e-18 64.8 0.1 1.2e-17 64.1 0.1 1.3 1 0 0 1 1 1 1 MATH domain HD_4 PF13328.6 CDJ89258.1 - 1.7e-24 86.3 0.1 2.2e-24 86.0 0.1 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.22 CDJ89258.1 - 6.5e-05 23.1 1.5 0.00023 21.4 1.5 2.0 1 1 0 1 1 1 1 HD domain FAM184 PF15665.5 CDJ89258.1 - 0.0047 16.7 0.4 0.0061 16.4 0.4 1.3 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B UPF0147 PF03685.13 CDJ89258.1 - 0.059 13.4 0.1 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) Integrase_H2C2 PF17921.1 CDJ89259.1 - 0.029 14.5 0.1 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 Integrase zinc binding domain DUF148 PF02520.17 CDJ89260.1 - 9.5e-19 67.5 7.3 1.2e-18 67.2 7.3 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 RTX_C PF08339.10 CDJ89260.1 - 0.0024 18.0 0.7 0.0031 17.6 0.7 1.2 1 0 0 1 1 1 1 RTX C-terminal domain Baculo_PEP_C PF04513.12 CDJ89260.1 - 0.012 15.6 0.6 0.015 15.4 0.6 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peripla_BP_2 PF01497.18 CDJ89260.1 - 0.06 12.9 0.5 0.072 12.6 0.5 1.2 1 0 0 1 1 1 0 Periplasmic binding protein SH3_1 PF00018.28 CDJ89261.1 - 1.2e-44 149.7 0.2 9.4e-11 41.2 0.0 4.3 4 0 0 4 4 4 4 SH3 domain SH3_9 PF14604.6 CDJ89261.1 - 4.7e-37 125.6 0.9 9.5e-10 38.2 0.0 4.2 4 0 0 4 4 4 4 Variant SH3 domain SH3_2 PF07653.17 CDJ89261.1 - 4.5e-26 90.3 0.0 1.9e-06 27.5 0.0 4.3 4 0 0 4 4 4 4 Variant SH3 domain DUF5348 PF17295.2 CDJ89261.1 - 0.047 13.6 0.1 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5348) MazE_antitoxin PF04014.18 CDJ89261.1 - 0.1 12.6 0.3 71 3.5 0.0 3.3 3 0 0 3 3 3 0 Antidote-toxin recognition MazE, bacterial antitoxin NTP_transf_2 PF01909.23 CDJ89262.1 - 5.9e-07 29.7 0.0 2.1e-06 27.9 0.0 2.0 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CDJ89262.1 - 0.00057 19.9 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase RRM_1 PF00076.22 CDJ89262.1 - 0.0071 16.1 0.7 0.023 14.5 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA_NucTransf2 PF09249.11 CDJ89262.1 - 0.073 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain PhnA_Zn_Ribbon PF08274.12 CDJ89262.1 - 0.18 11.8 1.1 0.35 10.8 0.3 1.9 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-met PF12874.7 CDJ89264.1 - 0.024 15.0 0.2 0.024 15.0 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CDJ89264.1 - 0.056 13.9 13.2 1 10.0 0.5 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ89264.1 - 0.12 13.3 13.5 5.7 8.1 0.5 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CDJ89264.1 - 0.27 11.6 6.7 3.5 8.0 0.3 2.9 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) AAA_11 PF13086.6 CDJ89264.1 - 5.8 6.6 7.5 8.4 6.1 7.5 1.2 1 0 0 1 1 1 0 AAA domain Hormone_recep PF00104.30 CDJ89266.1 - 0.00088 18.9 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor FYVE PF01363.21 CDJ89267.1 - 2.7e-17 62.7 6.1 7.2e-17 61.3 6.1 1.8 1 1 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.8 CDJ89267.1 - 6.4e-14 51.4 0.7 6.4e-14 51.4 0.7 3.2 3 0 0 3 3 3 1 Rabenosyn Rab binding domain ApoLp-III PF07464.11 CDJ89267.1 - 0.0045 17.1 2.3 0.081 13.0 0.0 2.7 2 1 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) Zf_RING PF16744.5 CDJ89267.1 - 0.011 15.8 1.0 0.23 11.6 2.7 2.3 2 0 0 2 2 2 0 KIAA1045 RING finger zf-Di19 PF05605.12 CDJ89267.1 - 0.019 15.3 0.0 0.019 15.3 0.0 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CLP_protease PF00574.23 CDJ89267.1 - 0.11 12.4 0.2 0.11 12.4 0.2 2.7 3 1 0 3 3 3 0 Clp protease Spidroin_N PF16763.5 CDJ89267.1 - 0.64 10.0 4.6 0.57 10.2 0.3 2.5 2 0 0 2 2 2 0 Major ampullate spidroin 1, spider silk protein 1, N-term Nnf1 PF03980.14 CDJ89267.1 - 0.87 10.0 4.2 0.56 10.6 1.2 2.2 2 0 0 2 2 2 0 Nnf1 FYVE_2 PF02318.16 CDJ89267.1 - 5.5 7.2 15.6 0.082 13.1 4.7 3.1 3 0 0 3 3 3 0 FYVE-type zinc finger HSP20 PF00011.21 CDJ89268.1 - 6.5e-15 55.1 0.0 9.1e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Methuselah_N PF06652.12 CDJ89268.1 - 0.094 12.6 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Methuselah N-terminus Lectin_C PF00059.21 CDJ89269.1 - 2.2e-16 60.5 0.3 4.4e-16 59.5 0.3 1.5 1 0 0 1 1 1 1 Lectin C-type domain VWA PF00092.28 CDJ89269.1 - 7.5e-14 52.3 0.0 1e-13 51.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CDJ89269.1 - 7.9e-07 29.7 0.1 1.4e-06 28.9 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Lectin_C PF00059.21 CDJ89270.1 - 7.9e-13 49.1 1.5 1e-12 48.8 0.4 1.7 1 1 0 1 1 1 1 Lectin C-type domain VWA PF00092.28 CDJ89270.1 - 1.4e-12 48.2 0.0 2e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CDJ89270.1 - 6.4e-06 26.8 0.1 1.5e-05 25.6 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 CDJ89270.1 - 0.2 11.6 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain UMP1 PF05348.11 CDJ89271.1 - 0.079 13.2 0.0 0.093 13.0 0.0 1.3 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 RVT_1 PF00078.27 CDJ89272.1 - 4.6e-22 78.6 0.0 1e-21 77.5 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Motile_Sperm PF00635.26 CDJ89274.1 - 1.5e-09 37.7 0.0 2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain TTR-52 PF01060.23 CDJ89275.1 - 3.9e-07 30.7 0.0 5.3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Transthyretin-like family RVT_1 PF00078.27 CDJ89276.1 - 2.4e-09 37.0 0.0 3.6e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TEX29 PF15839.5 CDJ89277.1 - 0.72 10.5 0.0 0.72 10.5 0.0 2.4 3 0 0 3 3 3 0 Testis-expressed sequence 29 protein 3HCDH_N PF02737.18 CDJ89278.1 - 1.2e-53 181.7 0.0 1.6e-53 181.2 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 CDJ89278.1 - 7.6e-22 77.7 0.0 2e-16 60.4 0.0 2.5 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ApbA PF02558.16 CDJ89278.1 - 0.18 11.5 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Terminase_6C PF17289.2 CDJ89278.1 - 0.19 11.8 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Terminase RNaseH-like domain CUB PF00431.20 CDJ89280.1 - 7.2e-14 52.1 0.0 6.1e-13 49.1 0.0 2.1 2 0 0 2 2 2 1 CUB domain Podoplanin PF05808.11 CDJ89280.1 - 0.062 13.4 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Podoplanin CUB PF00431.20 CDJ89281.1 - 3.9e-20 72.2 0.3 7.1e-13 48.9 0.0 3.5 3 0 0 3 3 3 2 CUB domain Kelch_1 PF01344.25 CDJ89285.1 - 9.2e-62 204.4 10.3 2e-14 52.9 0.1 5.2 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 CDJ89285.1 - 3.3e-37 125.6 1.9 4.1e-08 33.2 0.0 5.2 2 1 3 5 5 5 5 Kelch motif Kelch_2 PF07646.15 CDJ89285.1 - 5.2e-24 83.3 6.4 1e-05 25.3 0.2 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 CDJ89285.1 - 8e-15 54.7 2.0 0.0012 19.1 0.1 5.3 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_4 PF13418.6 CDJ89285.1 - 2.4e-14 53.1 4.9 0.0041 17.1 0.0 5.5 4 2 1 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ89285.1 - 3e-08 33.4 1.6 0.18 11.8 0.1 4.3 4 0 0 4 4 4 2 Kelch motif PQQ_3 PF13570.6 CDJ89285.1 - 0.00014 22.2 2.3 30 5.2 0.1 5.2 5 0 0 5 5 5 0 PQQ-like domain Glu_cyclase_2 PF05096.12 CDJ89285.1 - 0.0012 18.4 0.0 0.01 15.3 0.0 2.1 2 1 0 2 2 2 1 Glutamine cyclotransferase Mto2_bdg PF12808.7 CDJ89285.1 - 0.19 12.0 1.2 15 6.0 0.1 2.5 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region 7tm_1 PF00001.21 CDJ89286.1 - 2e-09 37.2 15.3 2.1e-09 37.1 14.4 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDJ89286.1 - 1.3e-06 28.0 15.5 0.00038 19.8 7.3 2.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 CDJ89286.1 - 3.2e-06 27.0 10.5 3.2e-06 27.0 10.5 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Prefoldin PF02996.17 CDJ89287.1 - 1.3e-12 47.6 2.3 2.5e-12 46.8 2.3 1.4 1 0 0 1 1 1 1 Prefoldin subunit CENP-X PF09415.10 CDJ89287.1 - 2.7e-07 30.8 0.0 7.4e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 CENP-S associating Centromere protein X DUF1878 PF08963.10 CDJ89287.1 - 2.5 8.6 5.8 2.3 8.7 0.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1878) EMC3_TMCO1 PF01956.16 CDJ89288.1 - 7.2e-56 188.6 0.2 7.2e-56 188.6 0.2 1.6 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like 3HCDH PF00725.22 CDJ89288.1 - 0.12 13.0 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Ras PF00071.22 CDJ89289.1 - 2.5e-55 186.5 0.6 3e-55 186.3 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ89289.1 - 3.1e-33 114.5 0.3 5e-33 113.9 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ89289.1 - 1.1e-15 57.5 0.3 1.7e-15 56.9 0.3 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ89289.1 - 1.3e-05 24.7 0.2 1.5e-05 24.5 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CDJ89289.1 - 0.0014 18.1 0.1 0.0023 17.4 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CDJ89289.1 - 0.0018 18.3 0.2 0.0049 16.9 0.2 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ89289.1 - 0.012 15.1 0.4 0.11 12.0 0.4 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 CDJ89289.1 - 0.014 15.1 0.8 0.092 12.5 0.8 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 CDJ89289.1 - 0.022 14.7 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 CDJ89289.1 - 0.033 14.2 0.1 0.06 13.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDJ89289.1 - 0.089 13.1 0.1 0.15 12.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDJ89289.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Ribosomal_60s PF00428.19 CDJ89291.1 - 3.8e-26 91.5 10.3 4.9e-26 91.1 10.3 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3391 PF11871.8 CDJ89291.1 - 0.033 14.7 0.3 0.046 14.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DNA_binding_1 PF01035.20 CDJ89292.1 - 3.2e-28 97.7 0.0 5.3e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain USP8_interact PF08941.10 CDJ89294.1 - 0.011 15.6 4.5 0.011 15.6 4.5 5.1 2 2 2 6 6 6 0 USP8 interacting Bap31_Bap29_C PF18035.1 CDJ89294.1 - 0.017 15.1 5.8 0.017 15.1 5.8 6.9 7 0 0 7 7 7 0 Bap31/Bap29 cytoplasmic coiled-coil domain Uso1_p115_C PF04871.13 CDJ89294.1 - 0.13 12.6 0.2 0.13 12.6 0.2 7.4 3 2 4 7 7 7 0 Uso1 / p115 like vesicle tethering protein, C terminal region KIF1B PF12423.8 CDJ89294.1 - 0.35 11.3 4.0 0.36 11.3 0.1 3.1 3 0 0 3 3 3 0 Kinesin protein 1B Rab5-bind PF09311.11 CDJ89295.1 - 2.6e-79 266.8 44.4 3.1e-79 266.6 44.4 1.0 1 0 0 1 1 1 1 Rabaptin-like protein FYVE PF01363.21 CDJ89295.1 - 2.3e-05 24.5 10.3 2.3e-05 24.5 10.3 2.5 2 1 0 2 2 2 1 FYVE zinc finger Filament PF00038.21 CDJ89295.1 - 0.00078 19.1 42.0 0.006 16.2 14.3 3.5 1 1 1 3 3 3 2 Intermediate filament protein Golgin_A5 PF09787.9 CDJ89295.1 - 0.031 13.8 47.8 0.4 10.1 32.5 2.9 1 1 1 2 2 2 0 Golgin subfamily A member 5 UPF0184 PF03670.13 CDJ89295.1 - 0.043 14.2 0.4 0.043 14.2 0.4 3.8 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0184) Mce4_CUP1 PF11887.8 CDJ89295.1 - 0.059 12.8 6.9 0.23 10.9 0.6 2.6 2 1 1 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF4686 PF15742.5 CDJ89295.1 - 0.51 9.4 48.7 0.56 9.3 16.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) DUF3540 PF12059.8 CDJ89295.1 - 0.71 9.7 12.8 0.85 9.4 6.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3540) Borrelia_REV PF03978.13 CDJ89295.1 - 4.2 7.3 16.2 0.56 10.2 6.2 3.1 2 1 1 3 3 3 0 Borrelia burgdorferi REV protein DZR PF12773.7 CDJ89295.1 - 5 7.2 13.5 6.7 6.8 2.1 3.3 2 1 1 3 3 3 0 Double zinc ribbon DUF948 PF06103.11 CDJ89295.1 - 7.7 6.8 10.2 4.9 7.5 0.2 3.2 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Glyco_hydro_85 PF03644.13 CDJ89296.1 - 2.4e-66 224.2 0.2 3.3e-66 223.8 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Peptidase_A6 PF01829.16 CDJ89296.1 - 0.21 10.9 0.1 0.31 10.3 0.1 1.2 1 0 0 1 1 1 0 Peptidase A6 family C4 PF01413.19 CDJ89297.1 - 5.8e-47 158.7 1.6 6.8e-43 145.6 0.2 2.0 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen EF-hand_13 PF17958.1 CDJ89300.1 - 1.9e-17 62.8 0.0 5.6e-17 61.3 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain Ig_3 PF13927.6 CDJ89302.1 - 1.2e-33 115.6 3.2 4.4e-09 36.8 0.0 7.0 8 0 0 8 8 7 4 Immunoglobulin domain I-set PF07679.16 CDJ89302.1 - 3.6e-32 110.3 0.0 5.6e-09 36.0 0.0 5.6 5 0 0 5 5 5 3 Immunoglobulin I-set domain Ig_2 PF13895.6 CDJ89302.1 - 1.9e-26 92.2 0.6 1.8e-06 28.2 0.0 6.8 6 1 0 6 6 6 3 Immunoglobulin domain ig PF00047.25 CDJ89302.1 - 2.5e-21 75.6 0.2 1e-05 25.6 0.0 6.3 6 0 0 6 6 6 4 Immunoglobulin domain fn3 PF00041.21 CDJ89302.1 - 9.5e-19 67.5 4.6 4.2e-06 27.0 0.4 5.0 4 1 0 4 4 4 4 Fibronectin type III domain V-set PF07686.17 CDJ89302.1 - 1e-10 41.7 6.6 0.24 11.6 0.1 7.5 6 3 1 8 8 8 4 Immunoglobulin V-set domain fn3_4 PF16794.5 CDJ89302.1 - 3.2e-05 23.8 0.2 0.0088 16.0 0.0 4.1 5 1 0 5 5 5 1 Fibronectin-III type domain Pur_ac_phosph_N PF16656.5 CDJ89302.1 - 0.0002 21.8 5.3 0.00026 21.5 0.2 3.4 4 0 0 4 4 3 1 Purple acid Phosphatase, N-terminal domain Ig_C17orf99 PF17736.1 CDJ89302.1 - 0.00057 19.9 0.1 0.21 11.7 0.0 3.2 3 0 0 3 3 3 1 C17orf99 Ig domain Ig_6 PF18452.1 CDJ89302.1 - 0.0016 17.9 0.0 3.6 7.2 0.0 3.8 4 0 0 4 4 4 1 Immunoglobulin domain Glyco_hydro_36C PF16874.5 CDJ89302.1 - 0.017 15.6 0.0 0.41 11.2 0.0 2.9 3 0 0 3 3 3 0 Glycosyl hydrolase family 36 C-terminal domain Interfer-bind PF09294.10 CDJ89302.1 - 0.024 14.9 0.0 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III IgGFc_binding PF17517.2 CDJ89303.1 - 1.8e-34 119.3 8.7 1.8e-34 119.3 8.7 2.1 2 0 0 2 2 2 2 IgGFc binding protein MFS_1 PF07690.16 CDJ89304.1 - 4.2e-46 157.5 23.7 4.2e-46 157.5 23.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Med20 PF08612.11 CDJ89306.1 - 1.5e-29 103.0 0.0 1.7e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex T6SS_TssF PF05947.12 CDJ89306.1 - 0.072 11.6 0.1 0.11 11.0 0.1 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssF Pyridoxal_deC PF00282.19 CDJ89307.1 - 7.8e-21 74.2 0.0 1.2e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CDJ89307.1 - 5.2e-07 29.0 0.0 8.2e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CDJ89307.1 - 7.3e-07 28.7 0.0 1.2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CDJ89307.1 - 6.2e-05 22.5 0.1 0.0001 21.7 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 CDJ89307.1 - 0.066 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase DUF3377 PF11857.8 CDJ89308.1 - 0.035 14.0 0.1 0.056 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Sre PF03125.18 CDJ89308.1 - 0.077 12.1 0.0 0.096 11.8 0.0 1.1 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor DUF3328 PF11807.8 CDJ89308.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) TUSC2 PF15000.6 CDJ89309.1 - 3.9e-27 94.8 0.1 4.5e-27 94.6 0.1 1.1 1 0 0 1 1 1 1 Tumour suppressor candidate 2 HGTP_anticodon PF03129.20 CDJ89310.1 - 4.3e-11 42.8 0.0 9.1e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CDJ89310.1 - 4.4e-08 33.3 0.0 8.7e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Promethin PF16015.5 CDJ89311.1 - 0.00015 21.6 22.2 0.0002 21.2 22.2 1.2 1 0 0 1 1 1 1 Promethin Mtc PF03820.17 CDJ89311.1 - 0.011 14.9 1.8 0.011 14.9 1.8 1.4 1 1 0 1 1 1 0 Tricarboxylate carrier EGF_2 PF07974.13 CDJ89312.1 - 0.00011 22.5 25.8 0.027 14.9 2.7 3.6 3 0 0 3 3 3 3 EGF-like domain Laminin_EGF PF00053.24 CDJ89312.1 - 0.026 14.7 22.6 5.2 7.3 5.6 3.5 1 1 2 3 3 3 0 Laminin EGF domain EGF PF00008.27 CDJ89312.1 - 0.46 10.8 0.3 0.46 10.8 0.3 4.1 3 2 0 3 3 3 0 EGF-like domain PCSK9_C3 PF18463.1 CDJ89312.1 - 1.1 9.5 10.8 1.4 9.2 3.7 2.5 1 1 1 2 2 2 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain PBP PF01161.20 CDJ89313.1 - 1.8e-20 73.6 0.1 2.6e-20 73.1 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein CDC73_N PF16050.5 CDJ89314.1 - 0.88 8.8 7.3 5.2 6.3 0.4 2.6 2 1 1 3 3 3 0 Paf1 complex subunit CDC73 N-terminal AT_hook PF02178.19 CDJ89314.1 - 0.95 9.6 11.6 0.041 13.7 5.2 2.4 2 0 0 2 2 2 0 AT hook motif TBPIP PF07106.13 CDJ89315.1 - 4.5e-18 64.9 0.3 1.2e-17 63.6 0.3 1.7 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain FlxA PF14282.6 CDJ89315.1 - 6e-06 26.2 2.7 9.8e-06 25.5 2.7 1.3 1 0 0 1 1 1 1 FlxA-like protein LZ3wCH PF18517.1 CDJ89315.1 - 0.00018 21.5 0.7 0.1 12.7 0.0 3.0 3 1 0 3 3 2 1 Leucine zipper with capping helix domain DUF4407 PF14362.6 CDJ89315.1 - 0.00083 18.8 5.5 0.00097 18.6 5.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Syntaxin PF00804.25 CDJ89315.1 - 0.0024 17.6 7.3 0.0035 17.0 7.3 1.2 1 0 0 1 1 1 1 Syntaxin Tropomyosin_1 PF12718.7 CDJ89315.1 - 0.0056 16.8 5.6 0.0056 16.8 5.6 1.5 1 1 0 1 1 1 1 Tropomyosin like NPV_P10 PF05531.12 CDJ89315.1 - 0.0081 16.6 3.1 0.04 14.4 3.1 2.2 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 CDJ89315.1 - 0.011 16.0 4.8 0.73 10.2 0.1 2.9 1 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Syntaxin_2 PF14523.6 CDJ89315.1 - 0.023 15.1 3.8 0.049 14.0 3.8 1.6 1 0 0 1 1 1 0 Syntaxin-like protein Utp11 PF03998.13 CDJ89315.1 - 0.023 14.6 4.4 0.028 14.4 4.4 1.1 1 0 0 1 1 1 0 Utp11 protein Atg14 PF10186.9 CDJ89315.1 - 0.044 12.9 7.0 0.058 12.5 7.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2730 PF10805.8 CDJ89315.1 - 0.046 13.8 0.7 0.12 12.5 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) V_ATPase_I PF01496.19 CDJ89315.1 - 0.046 11.6 3.3 0.053 11.4 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.20 CDJ89315.1 - 0.048 13.6 6.2 0.23 11.4 0.5 3.0 1 1 2 3 3 3 0 Prefoldin subunit COG5 PF10392.9 CDJ89315.1 - 0.072 13.3 5.1 0.14 12.3 5.1 1.5 1 1 0 1 1 1 0 Golgi transport complex subunit 5 DUF5595 PF18077.1 CDJ89315.1 - 0.072 13.2 5.3 0.29 11.3 0.6 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF5595) Allexi_40kDa PF05549.11 CDJ89315.1 - 0.077 12.5 2.1 0.1 12.1 2.1 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Baculo_PEP_C PF04513.12 CDJ89315.1 - 0.085 12.9 4.6 0.13 12.3 2.8 1.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.11 CDJ89315.1 - 0.1 13.2 5.0 0.16 12.5 4.2 1.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Fez1 PF06818.15 CDJ89315.1 - 0.1 13.0 5.1 0.16 12.4 5.1 1.2 1 0 0 1 1 1 0 Fez1 Lectin_N PF03954.14 CDJ89315.1 - 0.12 12.2 4.4 4.5 7.0 1.1 2.2 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain TMPIT PF07851.13 CDJ89315.1 - 0.15 11.2 3.3 0.2 10.9 3.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF5082 PF16888.5 CDJ89315.1 - 0.16 12.3 8.2 1.2 9.4 5.5 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Phage_GP20 PF06810.11 CDJ89315.1 - 0.16 11.8 11.2 0.7 9.7 11.2 1.9 1 1 0 1 1 1 0 Phage minor structural protein GP20 DUF4988 PF16378.5 CDJ89315.1 - 0.16 11.6 2.7 1.3 8.7 1.0 2.2 1 1 1 2 2 2 0 Domain of unknown function TPR_MLP1_2 PF07926.12 CDJ89315.1 - 0.18 11.9 8.2 0.58 10.2 8.1 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spectrin PF00435.21 CDJ89315.1 - 0.29 11.7 3.3 12 6.5 0.6 2.3 1 1 1 2 2 2 0 Spectrin repeat Cnn_1N PF07989.11 CDJ89315.1 - 0.29 11.3 4.1 4.7 7.4 0.6 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Spc7 PF08317.11 CDJ89315.1 - 0.31 9.9 9.7 0.55 9.1 9.7 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein FlaC_arch PF05377.11 CDJ89315.1 - 0.31 11.5 2.9 2.1 8.8 0.6 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) SKA2 PF16740.5 CDJ89315.1 - 0.39 10.5 5.3 0.38 10.6 2.7 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DivIC PF04977.15 CDJ89315.1 - 0.41 10.4 4.2 5.4 6.9 0.3 2.5 1 1 1 2 2 2 0 Septum formation initiator DUF2937 PF11157.8 CDJ89315.1 - 0.42 10.3 2.0 4.2 7.1 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) ZapB PF06005.12 CDJ89315.1 - 0.51 10.8 4.9 8.3 6.9 5.4 2.7 2 1 0 2 2 2 0 Cell division protein ZapB Matrilin_ccoil PF10393.9 CDJ89315.1 - 0.52 10.2 4.6 3.2 7.7 0.9 2.5 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin LPP PF04728.13 CDJ89315.1 - 1.2 9.5 7.0 0.93 9.9 0.3 2.7 1 1 1 2 2 2 0 Lipoprotein leucine-zipper DUF2203 PF09969.9 CDJ89315.1 - 1.4 9.7 6.2 4.1 8.2 0.2 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Swi5 PF07061.11 CDJ89315.1 - 2 8.6 6.1 16 5.7 0.5 2.9 1 1 0 2 2 2 0 Swi5 XhlA PF10779.9 CDJ89315.1 - 2 8.7 6.3 11 6.3 0.6 2.6 1 1 1 2 2 2 0 Haemolysin XhlA Spc24 PF08286.11 CDJ89315.1 - 2.1 8.7 6.9 4 7.7 0.5 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DASH_Dad3 PF08656.10 CDJ89315.1 - 2.1 8.5 7.2 42 4.3 4.7 3.3 2 1 0 2 2 2 0 DASH complex subunit Dad3 LMBR1 PF04791.16 CDJ89315.1 - 3.2 6.6 4.9 8.4 5.2 4.9 1.6 1 1 0 1 1 1 0 LMBR1-like membrane protein ABC_tran_CTD PF16326.5 CDJ89315.1 - 4.8 7.5 10.3 10 6.5 0.7 2.8 2 1 1 3 3 2 0 ABC transporter C-terminal domain Methyltransf_25 PF13649.6 CDJ89316.1 - 6.8e-12 45.9 0.0 1.2e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ89316.1 - 7.2e-12 45.9 0.2 4.4e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ89316.1 - 4.3e-11 42.8 0.0 7e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ89316.1 - 2.1e-10 40.7 0.0 5.3e-10 39.4 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ89316.1 - 7.3e-08 33.0 0.0 1.2e-07 32.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ89316.1 - 1.1e-05 25.0 0.0 1.4e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 CDJ89316.1 - 0.00011 21.7 0.0 0.00014 21.3 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB Rsm22 PF09243.10 CDJ89316.1 - 0.0079 15.5 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 MTS PF05175.14 CDJ89316.1 - 0.014 15.0 0.0 0.03 13.9 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain DOT1 PF08123.13 CDJ89316.1 - 0.037 13.6 0.0 0.14 11.7 0.0 1.7 1 1 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 CDJ89316.1 - 0.051 13.0 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 CDJ89316.1 - 0.15 11.4 0.0 0.26 10.5 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase domain RVT_1 PF00078.27 CDJ89319.1 - 4.8e-24 85.1 0.0 8e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SUKH-4 PF14435.6 CDJ89320.1 - 0.067 13.3 0.0 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 SUKH-4 immunity protein Col_cuticle_N PF01484.17 CDJ89322.1 - 4e-16 58.8 2.1 5.3e-16 58.4 2.1 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ89322.1 - 0.00015 21.4 96.2 1.8e+04 -25.8 96.2 3.0 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) zf-H2C2_2 PF13465.6 CDJ89323.1 - 0.037 14.5 1.9 0.037 14.5 1.9 2.8 3 0 0 3 3 3 0 Zinc-finger double domain RVT_1 PF00078.27 CDJ89324.1 - 6.8e-23 81.3 0.0 9e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MT-A70 PF05063.14 CDJ89325.1 - 9.6e-16 58.2 0.0 1.1e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 MT-A70 Collagen PF01391.18 CDJ89326.1 - 9e-18 63.8 131.0 7.4e-09 35.2 42.4 3.8 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ89326.1 - 8.1e-13 48.2 0.4 1.1e-12 47.8 0.4 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain His_Phos_2 PF00328.22 CDJ89327.1 - 7.1e-32 111.2 0.0 2.3e-29 103.0 0.0 3.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Peptidase_M8 PF01457.16 CDJ89327.1 - 7.3e-12 44.7 0.0 1.1e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Leishmanolysin ShK PF01549.24 CDJ89328.1 - 8.2e-09 35.9 4.4 1.1e-08 35.5 4.4 1.2 1 0 0 1 1 1 1 ShK domain-like PLAC PF08686.11 CDJ89328.1 - 0.0056 17.4 0.7 0.018 15.8 0.7 1.9 1 1 0 1 1 1 1 PLAC (protease and lacunin) domain PAP_RNA-bind PF04926.15 CDJ89328.1 - 0.13 11.9 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain Brix PF04427.18 CDJ89331.1 - 1.7e-27 96.8 0.3 2.6e-27 96.2 0.3 1.2 1 0 0 1 1 1 1 Brix domain NADH_B2 PF14813.6 CDJ89332.1 - 1.2e-14 53.8 2.1 1.2e-14 53.8 2.1 1.6 2 0 0 2 2 2 1 NADH dehydrogenase 1 beta subcomplex subunit 2 RVT_1 PF00078.27 CDJ89333.1 - 3.6e-22 79.0 0.0 4.6e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Methyltr_RsmF_N PF17125.5 CDJ89333.1 - 0.13 12.8 0.1 0.7 10.4 0.1 2.0 1 1 1 2 2 2 0 N-terminal domain of 16S rRNA methyltransferase RsmF Voltage_CLC PF00654.20 CDJ89334.1 - 6.5e-78 262.4 28.1 6.5e-78 262.4 28.1 1.6 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CDJ89334.1 - 8.2e-07 29.4 0.5 0.0015 18.9 0.1 2.7 2 0 0 2 2 2 2 CBS domain Phage_holin_4_1 PF05105.12 CDJ89334.1 - 3.6 7.8 7.9 0.37 10.9 1.5 2.7 2 1 0 2 2 2 0 Bacteriophage holin family Nup35_RRM_2 PF14605.6 CDJ89335.1 - 3.5e-09 36.5 0.1 0.0027 17.7 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 CDJ89335.1 - 1e-07 31.6 0.0 0.0039 17.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 CDJ89335.1 - 0.0031 17.4 4.2 0.0052 16.7 4.2 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ89335.1 - 0.028 14.5 2.8 0.047 13.8 2.8 1.4 1 0 0 1 1 1 0 Zinc finger domain Nup35_RRM PF05172.13 CDJ89335.1 - 0.078 13.0 0.2 4.8 7.2 0.0 2.8 2 2 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF4140 PF13600.6 CDJ89335.1 - 0.11 12.9 2.2 2.7 8.5 0.6 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Prominin PF05478.11 CDJ89335.1 - 2 6.3 5.0 2.7 5.8 5.0 1.1 1 0 0 1 1 1 0 Prominin DUF3496 PF12001.8 CDJ89335.1 - 2.8 8.4 6.6 0.87 10.0 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) Spc7 PF08317.11 CDJ89335.1 - 4.2 6.2 12.2 6.7 5.5 12.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Snapin_Pallidin PF14712.6 CDJ89335.1 - 4.7 7.7 7.4 0.59 10.6 2.5 1.9 2 0 0 2 2 2 0 Snapin/Pallidin PHM7_cyt PF14703.6 CDJ89335.1 - 7.8 6.7 13.6 5.4 7.2 4.3 3.4 2 2 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Peptidase_S28 PF05577.12 CDJ89336.1 - 5.7e-128 427.4 5.3 7.4e-128 427.0 5.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 CDJ89336.1 - 0.00017 21.3 0.4 0.00029 20.6 0.4 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold RRM_1 PF00076.22 CDJ89336.1 - 0.0015 18.3 0.0 0.0038 17.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDJ89336.1 - 0.0033 17.4 0.0 0.0069 16.4 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Peptidase_S28 PF05577.12 CDJ89337.1 - 9.5e-75 252.0 8.2 1.4e-49 169.1 0.3 4.0 1 1 3 4 4 4 4 Serine carboxypeptidase S28 Peptidase_S28 PF05577.12 CDJ89338.1 - 5e-61 206.8 0.1 6.8e-61 206.4 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 CDJ89338.1 - 0.0023 17.6 0.1 0.0039 16.9 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold RRM_1 PF00076.22 CDJ89338.1 - 0.0055 16.5 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDJ89338.1 - 0.008 16.2 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif TauE PF01925.19 CDJ89339.1 - 3.8e-16 59.4 25.9 3.8e-16 59.4 25.9 1.5 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE TauE PF01925.19 CDJ89341.1 - 2.3e-16 60.1 21.1 2.3e-16 60.1 21.1 2.1 1 1 1 2 2 2 1 Sulfite exporter TauE/SafE RseC_MucC PF04246.12 CDJ89341.1 - 4.8 7.1 6.7 0.98 9.4 0.3 2.9 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Neur_chan_memb PF02932.16 CDJ89343.1 - 2.7e-65 220.8 15.3 1.3e-36 126.9 4.1 4.1 2 2 0 3 3 3 3 Neurotransmitter-gated ion-channel transmembrane region YebO PF13974.6 CDJ89343.1 - 0.47 10.6 2.9 5.6 7.1 0.2 2.7 2 0 0 2 2 2 0 YebO-like protein Neur_chan_memb PF02932.16 CDJ89344.1 - 1.3e-08 35.2 0.0 0.00014 22.1 0.0 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region PLAT PF01477.23 CDJ89345.1 - 2.3e-05 24.9 0.0 2.8e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 PLAT/LH2 domain ATS3 PF06232.11 CDJ89345.1 - 0.00027 20.9 0.0 0.00032 20.6 0.0 1.2 1 0 0 1 1 1 1 Embryo-specific protein 3, (ATS3) YqgF PF14639.6 CDJ89345.1 - 0.14 11.9 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 La PF05383.17 CDJ89346.1 - 2.9e-20 72.1 0.3 7.7e-20 70.7 0.0 1.9 2 0 0 2 2 2 1 La domain Pkinase PF00069.25 CDJ89347.1 - 2.7e-56 190.8 0.0 5.2e-56 189.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ89347.1 - 1.5e-41 142.4 0.0 2.6e-41 141.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ89347.1 - 2.2e-06 27.2 0.0 4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CDJ89347.1 - 5.8e-06 26.4 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ89347.1 - 2.4e-05 23.3 0.3 5.4e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 CDJ89347.1 - 0.0013 18.4 0.2 0.0013 18.4 0.2 1.8 2 0 0 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 CDJ89347.1 - 0.0038 16.2 0.4 0.0038 16.2 0.4 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Arm PF00514.23 CDJ89347.1 - 0.007 16.4 0.1 0.2 11.7 0.1 3.0 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat Pox_ser-thr_kin PF05445.11 CDJ89347.1 - 0.018 14.0 0.8 0.035 13.1 0.3 1.5 1 1 1 2 2 2 0 Poxvirus serine/threonine protein kinase HEAT_2 PF13646.6 CDJ89347.1 - 0.042 14.2 0.4 1.5 9.3 0.1 2.8 3 0 0 3 3 3 0 HEAT repeats Rcd1 PF04078.13 CDJ89347.1 - 0.043 13.1 0.7 0.096 12.0 0.7 1.5 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like Neisseria_TspB PF05616.13 CDJ89349.1 - 0.098 11.1 9.2 0.12 10.9 9.2 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein LIM PF00412.22 CDJ89350.1 - 7.3e-36 122.2 34.7 7.1e-13 48.6 7.1 3.1 3 0 0 3 3 3 3 LIM domain Mut7-C PF01927.16 CDJ89350.1 - 0.027 14.6 4.1 0.027 14.6 4.1 3.5 3 1 2 5 5 5 0 Mut7-C RNAse domain zf-met PF12874.7 CDJ89350.1 - 8.5 6.9 18.5 59 4.2 0.8 5.5 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDJ89353.1 - 0.00013 22.2 4.9 0.082 13.2 0.0 3.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDJ89353.1 - 0.00086 19.6 2.8 0.028 14.8 0.2 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 CDJ89353.1 - 0.043 13.7 2.0 6.1 6.8 0.2 2.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2 PF00096.26 CDJ89353.1 - 0.094 13.2 5.5 1.5 9.4 0.0 3.5 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ89353.1 - 0.16 12.9 9.6 2.8 9.0 0.3 3.8 4 1 0 4 4 4 0 C2H2-type zinc finger WH1 PF00568.23 CDJ89354.1 - 1e-15 57.6 0.0 1.5e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 CDJ89354.1 - 3.1e-15 55.4 0.3 1.9e-06 27.5 0.0 2.5 2 0 0 2 2 2 2 WH2 motif PBD PF00786.28 CDJ89354.1 - 6.3e-12 45.7 0.2 1.3e-11 44.6 0.2 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain VHS PF00790.19 CDJ89355.1 - 8.2e-45 152.1 0.1 8.2e-45 152.1 0.1 2.5 3 0 0 3 3 3 1 VHS domain FYVE PF01363.21 CDJ89355.1 - 3.5e-19 68.7 9.1 7.4e-19 67.7 9.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CDJ89355.1 - 0.0013 19.0 5.7 0.0013 19.0 5.7 1.9 2 0 0 2 2 2 1 FYVE-type zinc finger UIM PF02809.20 CDJ89355.1 - 0.022 14.7 3.6 0.051 13.5 3.6 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif DZR PF12773.7 CDJ89355.1 - 0.16 12.0 9.8 9.7 6.3 7.5 3.1 2 1 1 3 3 3 0 Double zinc ribbon DUF4428 PF14471.6 CDJ89355.1 - 0.7 9.9 5.1 0.22 11.5 1.3 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4428) zf-RING_5 PF14634.6 CDJ89355.1 - 4.5 7.3 16.7 6.4 6.8 12.1 2.7 2 1 1 3 3 3 0 zinc-RING finger domain TTR-52 PF01060.23 CDJ89357.1 - 2.2e-13 50.7 0.0 2.6e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Transthyretin-like family TTR-52 PF01060.23 CDJ89358.1 - 0.00059 20.5 0.0 0.00082 20.0 0.0 1.2 1 0 0 1 1 1 1 Transthyretin-like family Adaptin_N PF01602.20 CDJ89359.1 - 6.3e-15 54.7 0.1 8.6e-15 54.3 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 CDJ89359.1 - 0.00064 19.9 0.0 0.0016 18.6 0.0 1.6 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain TTR-52 PF01060.23 CDJ89359.1 - 0.1 13.3 0.0 0.2 12.4 0.0 1.4 1 0 0 1 1 1 0 Transthyretin-like family MRP-S32 PF10210.9 CDJ89360.1 - 4.3e-16 59.2 0.2 5.6e-16 58.9 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S32 BPL_LplA_LipB PF03099.19 CDJ89361.1 - 2.2e-07 30.8 0.0 3.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF3624 PF12292.8 CDJ89362.1 - 0.076 13.4 0.0 0.09 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3624) Baculo_p24 PF05073.12 CDJ89363.1 - 0.0012 18.7 1.5 0.0018 18.1 1.5 1.3 1 0 0 1 1 1 1 Baculovirus P24 capsid protein PhaP_Bmeg PF09602.10 CDJ89363.1 - 0.01 15.8 2.8 0.012 15.6 2.8 1.1 1 0 0 1 1 1 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Apolipoprotein PF01442.18 CDJ89363.1 - 0.014 15.2 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Phage_int_SAM_6 PF18644.1 CDJ89363.1 - 0.015 15.3 0.6 0.02 14.9 0.6 1.3 1 0 0 1 1 1 0 Phage integrase SAM-like domain DUF1664 PF07889.12 CDJ89363.1 - 0.028 14.4 1.3 0.049 13.7 1.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Gp-FAR-1 PF05823.12 CDJ89363.1 - 0.035 14.5 3.3 4.6 7.6 3.3 2.2 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Rab5-bind PF09311.11 CDJ89363.1 - 0.042 13.2 3.4 0.05 13.0 3.4 1.1 1 0 0 1 1 1 0 Rabaptin-like protein DUF948 PF06103.11 CDJ89363.1 - 0.053 13.8 2.6 0.21 11.9 2.6 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) LPD11 PF18824.1 CDJ89363.1 - 0.064 13.4 0.0 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 Large polyvalent protein-associated domain 11 DUF2203 PF09969.9 CDJ89363.1 - 0.089 13.5 0.7 0.14 12.9 0.7 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF2524 PF10732.9 CDJ89363.1 - 0.1 12.9 1.6 0.27 11.5 1.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2524) DUF4201 PF13870.6 CDJ89363.1 - 0.11 12.2 6.2 0.53 10.0 1.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF4148 PF13663.6 CDJ89363.1 - 0.13 12.5 0.0 1.5 9.1 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4148) PAX PF00292.18 CDJ89365.1 - 6e-70 233.0 0.6 8.2e-70 232.5 0.6 1.2 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 CDJ89365.1 - 0.0004 20.1 0.0 0.00085 19.1 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 CDJ89365.1 - 0.0048 17.5 0.0 0.29 11.8 0.0 2.3 1 1 1 2 2 2 2 Homeodomain-like domain HTH_Tnp_IS1 PF12759.7 CDJ89365.1 - 0.021 14.5 0.0 0.061 12.9 0.0 1.8 1 0 0 1 1 1 0 InsA C-terminal domain RNB PF00773.19 CDJ89366.1 - 3.2e-96 322.5 0.0 7e-96 321.4 0.0 1.6 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 CDJ89366.1 - 4.8e-19 68.2 0.0 1e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 CDJ89366.1 - 1.5e-09 37.8 0.1 3e-07 30.5 0.0 3.1 3 0 0 3 3 3 1 Cold shock domain Rrp44_S1 PF17215.3 CDJ89366.1 - 2.6e-07 30.5 2.6 1.3e-06 28.2 2.6 2.2 1 1 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 CDJ89366.1 - 4.5e-07 29.7 0.0 1.9e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 Rrp44-like cold shock domain OB_RNB PF08206.11 CDJ89366.1 - 0.0025 17.5 0.0 0.011 15.4 0.0 2.1 2 0 0 2 2 2 1 Ribonuclease B OB domain MRP-L47 PF06984.13 CDJ89369.1 - 1.1e-29 102.3 0.4 1.1e-29 102.3 0.4 1.8 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Rpp20 PF12328.8 CDJ89371.1 - 8.4e-12 45.2 0.0 8.2e-09 35.5 0.0 2.2 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 CDJ89371.1 - 2e-10 40.3 0.4 3e-10 39.7 0.4 1.3 1 0 0 1 1 1 1 Alba Phosducin PF02114.16 CDJ89372.1 - 6.2e-22 77.8 0.4 1.5e-21 76.6 0.4 1.6 1 0 0 1 1 1 1 Phosducin Pyr_redox_2 PF07992.14 CDJ89372.1 - 5.3e-13 48.9 0.0 4.9e-09 35.8 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDJ89372.1 - 0.017 15.3 0.0 0.098 12.9 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CDJ89372.1 - 0.021 15.4 0.1 1.1 9.9 0.0 3.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDJ89372.1 - 0.059 12.6 0.1 5.8 6.1 0.0 2.5 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 CDJ89372.1 - 0.14 12.1 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding NPR3 PF03666.13 CDJ89373.1 - 3e-20 72.5 2.4 8e-15 54.6 1.5 3.0 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 DUF659 PF04937.15 CDJ89373.1 - 0.093 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) HTH_47 PF16221.5 CDJ89373.1 - 0.19 11.3 0.0 7.4 6.2 0.0 2.4 2 0 0 2 2 2 0 winged helix-turn-helix Prefoldin PF02996.17 CDJ89374.1 - 3.6e-13 49.5 1.7 4.9e-13 49.0 1.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit CENP-X PF09415.10 CDJ89375.1 - 2e-07 31.2 0.0 2.9e-07 30.7 0.0 1.4 1 1 0 1 1 1 1 CENP-S associating Centromere protein X EMC3_TMCO1 PF01956.16 CDJ89376.1 - 7.2e-56 188.6 0.2 7.2e-56 188.6 0.2 1.6 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like 3HCDH PF00725.22 CDJ89376.1 - 0.12 13.0 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Ras PF00071.22 CDJ89377.1 - 2.5e-55 186.5 0.6 3e-55 186.3 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ89377.1 - 3.1e-33 114.5 0.3 5e-33 113.9 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ89377.1 - 1.1e-15 57.5 0.3 1.7e-15 56.9 0.3 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ89377.1 - 1.3e-05 24.7 0.2 1.5e-05 24.5 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CDJ89377.1 - 0.0014 18.1 0.1 0.0023 17.4 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CDJ89377.1 - 0.0018 18.3 0.2 0.0049 16.9 0.2 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ89377.1 - 0.012 15.1 0.4 0.11 12.0 0.4 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 CDJ89377.1 - 0.014 15.1 0.8 0.092 12.5 0.8 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 CDJ89377.1 - 0.022 14.7 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 CDJ89377.1 - 0.033 14.2 0.1 0.06 13.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDJ89377.1 - 0.089 13.1 0.1 0.15 12.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDJ89377.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Ribosomal_60s PF00428.19 CDJ89379.1 - 3.4e-09 37.2 0.1 4.2e-09 36.9 0.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Exo_endo_phos_2 PF14529.6 CDJ89380.1 - 4.6e-05 23.3 0.2 0.00015 21.6 0.0 2.0 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ89380.1 - 7.8e-05 22.3 0.1 0.00022 20.8 0.0 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF5106 PF17127.4 CDJ89380.1 - 0.066 13.5 0.2 0.34 11.2 0.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5106) RVT_1 PF00078.27 CDJ89381.1 - 3.3e-24 85.6 0.0 6e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Choline_kinase PF01633.20 CDJ89382.1 - 7.1e-42 143.4 0.0 1e-41 142.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CDJ89382.1 - 4.7e-11 43.1 0.0 6.8e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CDJ89382.1 - 0.00053 19.4 0.1 0.0012 18.2 0.1 1.5 2 0 0 2 2 2 1 Ecdysteroid kinase FAM193_C PF15914.5 CDJ89382.1 - 0.2 11.5 0.9 0.63 9.8 0.3 2.1 2 0 0 2 2 2 0 FAM193 family C-terminal COesterase PF00135.28 CDJ89383.1 - 1.3e-96 324.5 0.0 1.4e-96 324.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDJ89383.1 - 3.3e-08 33.7 0.4 1.5e-07 31.5 0.4 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CDJ89383.1 - 0.0042 16.0 0.1 0.27 10.1 0.0 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 CDJ89383.1 - 0.071 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CDJ89383.1 - 0.085 13.4 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family UQ_con PF00179.26 CDJ89385.1 - 1.7e-33 115.2 1.0 7e-17 61.4 0.1 2.0 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme DUF4727 PF15856.5 CDJ89385.1 - 0.19 11.3 0.0 0.25 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4727) zf-C2HC_2 PF13913.6 CDJ89387.1 - 4.9e-09 35.9 2.5 7.7e-09 35.2 2.5 1.3 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 CDJ89387.1 - 0.032 14.7 0.1 0.066 13.7 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ89387.1 - 0.074 13.9 0.6 0.17 12.8 0.6 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger I-set PF07679.16 CDJ89388.1 - 1.6e-39 133.8 0.0 2.7e-13 49.8 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ89388.1 - 2.1e-25 89.1 0.0 1.3e-09 38.5 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 CDJ89388.1 - 2.7e-22 78.7 0.0 1e-07 32.0 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 CDJ89388.1 - 8e-14 51.7 0.0 0.00082 19.7 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 CDJ89388.1 - 1.2e-11 44.8 0.1 0.00075 19.6 0.0 3.8 3 1 0 3 3 3 2 Immunoglobulin V-set domain Ig_6 PF18452.1 CDJ89388.1 - 1.9e-06 27.3 0.0 0.11 12.1 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain Ig_4 PF16680.5 CDJ89388.1 - 2.6e-05 24.4 0.2 1.2 9.4 0.0 4.2 3 2 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 CDJ89388.1 - 2.9e-05 24.4 0.9 1.4 9.4 0.0 4.2 3 2 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 CDJ89388.1 - 0.00024 21.1 0.1 1.9 8.6 0.0 3.4 3 1 0 3 3 3 2 Izumo-like Immunoglobulin domain C1-set PF07654.15 CDJ89388.1 - 0.004 17.5 0.0 2 8.9 0.0 2.6 3 0 0 3 3 3 1 Immunoglobulin C1-set domain Receptor_2B4 PF11465.8 CDJ89388.1 - 0.0051 17.0 0.1 9.5 6.5 0.0 3.3 3 0 0 3 3 3 1 Natural killer cell receptor 2B4 V-set_CD47 PF08204.11 CDJ89388.1 - 0.0068 16.4 0.3 0.9 9.5 0.0 3.0 3 1 0 3 3 3 1 CD47 immunoglobulin-like domain NGP1NT PF08153.12 CDJ89388.1 - 0.041 14.0 0.0 0.082 13.1 0.0 1.4 1 0 0 1 1 1 0 NGP1NT (NUC091) domain C2-set_2 PF08205.12 CDJ89388.1 - 0.067 13.3 0.0 3.3 7.9 0.0 2.7 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain NTP_transf_9 PF04248.12 CDJ89388.1 - 0.089 12.7 0.2 6.5 6.7 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF427) HTH_IclR PF09339.10 CDJ89389.1 - 0.031 14.1 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain DDE_3 PF13358.6 CDJ89389.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease MarR_2 PF12802.7 CDJ89389.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 MarR family IN_DBD_C PF00552.21 CDJ89390.1 - 0.57 9.5 6.8 18 4.7 0.1 4.0 4 0 0 4 4 4 0 Integrase DNA binding domain 7TM_GPCR_Srv PF10323.9 CDJ89391.1 - 9.5e-36 123.6 25.9 9.5e-36 123.6 25.9 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_1 PF00001.21 CDJ89391.1 - 1.1e-07 31.5 21.8 1.1e-07 31.5 21.8 2.1 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Motile_Sperm PF00635.26 CDJ89392.1 - 4.8e-09 36.0 0.0 7e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain SRA1 PF07304.11 CDJ89392.1 - 0.094 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) DNA_pol3_gamma3 PF12169.8 CDJ89392.1 - 0.16 11.9 0.0 5 7.0 0.0 2.1 1 1 1 2 2 2 0 DNA polymerase III subunits gamma and tau domain III Patched PF02460.18 CDJ89395.1 - 1.4e-22 79.7 6.2 1.5e-22 79.5 6.2 1.0 1 0 0 1 1 1 1 Patched family SecD_SecF PF02355.16 CDJ89395.1 - 0.0023 17.3 0.5 0.0026 17.1 0.5 1.1 1 0 0 1 1 1 1 Protein export membrane protein BTB PF00651.31 CDJ89396.1 - 8.1e-16 58.2 2.4 7.9e-07 29.3 0.0 2.5 3 0 0 3 3 3 2 BTB/POZ domain HTH_28 PF13518.6 CDJ89396.1 - 0.11 12.6 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DNA_pol_phi PF04931.13 CDJ89397.1 - 1.2 7.2 3.1 1.7 6.7 3.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Csm1_N PF18504.1 CDJ89398.1 - 0.00014 22.1 4.1 0.0012 19.2 3.6 2.1 1 1 1 2 2 2 1 Csm1 N-terminal domain CCDC158 PF15921.5 CDJ89398.1 - 0.0018 16.2 0.3 0.0019 16.1 0.3 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 158 THOC7 PF05615.13 CDJ89398.1 - 0.007 16.6 1.3 0.0096 16.2 1.3 1.2 1 0 0 1 1 1 1 Tho complex subunit 7 Bap31_Bap29_C PF18035.1 CDJ89398.1 - 0.26 11.3 3.2 3.3 7.8 0.5 2.2 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Pkinase_Tyr PF07714.17 CDJ89399.1 - 3.9e-55 186.9 0.1 6.3e-55 186.2 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ89399.1 - 7.7e-34 117.2 0.0 1.2e-33 116.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDJ89399.1 - 6.9e-06 26.1 0.4 5.4e-05 23.2 0.4 2.4 1 1 0 1 1 1 1 SH2 domain Kinase-like PF14531.6 CDJ89399.1 - 0.0012 18.3 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ89400.1 - 3.8e-53 180.4 0.0 5.5e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ89400.1 - 1.4e-33 116.4 0.0 1.9e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDJ89400.1 - 8.7e-08 32.2 0.0 1.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 SH2 domain Kinase-like PF14531.6 CDJ89400.1 - 0.013 14.9 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like FancD2 PF14631.6 CDJ89402.1 - 2.2e-14 52.0 12.0 2e-05 22.3 0.1 3.6 4 0 0 4 4 4 3 Fanconi anaemia protein FancD2 nuclease FANCI_S2 PF14676.6 CDJ89402.1 - 0.00011 22.5 0.5 0.00097 19.5 0.2 2.5 1 1 1 2 2 2 1 FANCI solenoid 2 CAP_GLY PF01302.25 CDJ89403.1 - 8.9e-15 54.5 0.5 1e-11 44.7 0.3 3.2 3 0 0 3 3 3 2 CAP-Gly domain Ribosomal_S8 PF00410.19 CDJ89404.1 - 3.8e-23 81.8 0.0 5.6e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S8 IMS_C PF11799.8 CDJ89405.1 - 4.3e-10 40.3 0.0 7.4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS PF00817.20 CDJ89405.1 - 0.0017 18.4 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family DUF202 PF02656.15 CDJ89406.1 - 1.8 9.1 9.4 0.74 10.3 2.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF2157 PF09925.9 CDJ89406.1 - 3.4 7.4 9.3 31 4.3 9.3 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF2142 PF09913.9 CDJ89406.1 - 6.9 5.4 10.3 0.34 9.7 3.8 1.9 1 1 2 3 3 3 0 Predicted membrane protein (DUF2142) TFIID-18kDa PF02269.16 CDJ89407.1 - 0.0052 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit gpD PF02925.16 CDJ89407.1 - 0.08 12.9 0.1 0.18 11.8 0.1 1.5 1 1 0 1 1 1 0 Bacteriophage scaffolding protein D NAD_Gly3P_dh_N PF01210.23 CDJ89408.1 - 3.2e-53 179.9 0.1 4.7e-53 179.4 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 CDJ89408.1 - 2.8e-45 154.1 0.0 8.1e-45 152.6 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 CDJ89408.1 - 0.026 15.1 0.1 5.1 7.8 0.0 3.0 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent VPS9 PF02204.18 CDJ89409.1 - 6.2e-27 93.8 0.1 1.8e-26 92.4 0.0 1.8 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 CDJ89409.1 - 4.5e-19 68.5 1.4 1.3e-18 67.0 1.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) zf-A20 PF01754.16 CDJ89409.1 - 8.1e-11 41.7 5.4 8.1e-11 41.7 5.4 2.0 2 0 0 2 2 2 1 A20-like zinc finger HTH_11 PF08279.12 CDJ89409.1 - 0.011 15.6 0.0 0.039 13.9 0.0 1.9 1 0 0 1 1 1 0 HTH domain CCAP PF11105.8 CDJ89409.1 - 0.021 14.8 0.0 0.056 13.4 0.0 1.7 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a GatB_Yqey PF02637.18 CDJ89409.1 - 0.055 13.3 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 GatB domain Snapin_Pallidin PF14712.6 CDJ89409.1 - 0.072 13.5 2.3 0.72 10.3 0.2 2.6 2 0 0 2 2 2 0 Snapin/Pallidin zinc_ribbon_11 PF11682.8 CDJ89409.1 - 0.073 13.1 2.4 0.43 10.6 0.1 2.5 2 0 0 2 2 2 0 Probable zinc-ribbon DUF4709 PF15821.5 CDJ89409.1 - 3.6 7.9 5.6 7.9 6.8 0.8 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4709) DUF5641 PF18701.1 CDJ89410.1 - 1.1e-13 51.2 0.1 3.5e-13 49.5 0.0 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF5641) RAI1 PF08652.11 CDJ89410.1 - 0.0052 17.0 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease rve PF00665.26 CDJ89410.1 - 0.082 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain CAF20 PF17052.5 CDJ89411.1 - 0.21 11.7 5.7 0.25 11.5 5.7 1.1 1 0 0 1 1 1 0 Cap associated factor DUF2722 PF10846.8 CDJ89411.1 - 0.58 9.0 6.5 0.65 8.9 6.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Bestrophin PF01062.21 CDJ89412.1 - 4.3e-22 78.9 0.4 4.7e-22 78.7 0.4 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Pkinase PF00069.25 CDJ89413.1 - 5.6e-57 193.1 0.0 1.2e-56 192.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ89413.1 - 1.3e-44 152.5 0.0 2.5e-44 151.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 CDJ89413.1 - 7.3e-16 58.2 3.8 7.3e-16 58.2 3.8 3.2 3 0 0 3 3 3 2 Oxidative-stress-responsive kinase 1 C-terminal domain FLYWCH_u PF16662.5 CDJ89413.1 - 0.081 13.0 0.2 0.26 11.4 0.2 1.9 1 0 0 1 1 1 0 FLYWCH-type zinc finger-containing protein 1 DUF1676 PF07898.13 CDJ89413.1 - 9.6 6.2 8.7 25 4.9 8.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) WD40 PF00400.32 CDJ89414.1 - 3.5e-10 40.3 14.9 0.37 11.7 0.4 7.6 7 0 0 7 7 7 4 WD domain, G-beta repeat zinc_ribbon_16 PF17034.5 CDJ89414.1 - 1.4e-06 28.5 9.8 1.4e-06 28.5 9.8 2.0 1 1 0 1 1 1 1 Zinc-ribbon like family ANAPC4_WD40 PF12894.7 CDJ89414.1 - 0.00053 20.2 0.3 0.087 13.1 0.3 3.8 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 CDJ89414.1 - 0.077 11.9 0.1 0.15 10.9 0.1 1.4 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain Zn_ribbon_17 PF17120.5 CDJ89414.1 - 1.7 8.3 26.3 1.4 8.6 23.0 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CDJ89414.1 - 2.9 8.0 12.3 7.2 6.7 12.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger ABC2_membrane_3 PF12698.7 CDJ89415.1 - 1.3e-11 44.3 19.8 2.4e-11 43.4 19.8 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein Cadherin PF00028.17 CDJ89416.1 - 2.9e-197 639.9 11.4 9.3e-17 61.3 0.0 18.6 18 0 0 18 18 18 18 Cadherin domain Cadherin_2 PF08266.12 CDJ89416.1 - 5.6e-08 32.5 0.0 26 4.7 0.0 8.9 10 0 0 10 10 10 1 Cadherin-like Cadherin_3 PF16184.5 CDJ89416.1 - 1.7e-07 31.3 8.8 7.5 6.6 0.0 8.7 7 1 1 8 8 8 3 Cadherin-like RET_CLD1 PF17756.1 CDJ89416.1 - 0.0078 16.5 0.0 58 4.0 0.0 5.4 4 0 0 4 4 4 0 RET Cadherin like domain 1 Y_Y_Y PF07495.13 CDJ89416.1 - 0.076 13.0 0.0 7.6 6.6 0.0 4.0 4 0 0 4 4 4 0 Y_Y_Y domain Cadherin_4 PF17803.1 CDJ89416.1 - 1.6 9.4 44.4 0.16 12.6 0.9 10.7 12 0 0 12 12 12 0 Bacterial cadherin-like domain LRR_4 PF12799.7 CDJ89417.1 - 0.00018 21.8 18.3 1.1 9.8 0.4 6.6 4 2 2 6 6 6 2 Leucine Rich repeats (2 copies) F-box PF00646.33 CDJ89417.1 - 0.00027 20.7 3.1 0.0015 18.4 1.1 3.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CDJ89417.1 - 0.0032 17.3 0.6 0.0032 17.3 0.6 2.9 3 0 0 3 3 3 1 F-box-like DUF4717 PF15838.5 CDJ89417.1 - 0.13 12.3 0.6 0.24 11.4 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4717) LRR_8 PF13855.6 CDJ89417.1 - 0.61 9.9 15.4 6.2 6.7 0.1 5.4 6 1 0 6 6 6 0 Leucine rich repeat TPR_1 PF00515.28 CDJ89418.1 - 8.3e-18 63.4 6.6 0.0013 18.4 0.0 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ89418.1 - 3.4e-17 61.1 12.0 0.0017 18.4 0.0 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ89418.1 - 8.2e-15 53.7 15.6 0.0091 16.0 0.0 7.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ89418.1 - 9.8e-12 45.3 4.6 4.5e-05 24.0 0.2 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ89418.1 - 1.1e-09 38.4 4.8 0.0002 21.5 0.7 6.2 5 1 2 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ89418.1 - 1.6e-09 37.7 9.7 0.098 13.5 0.0 6.9 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ89418.1 - 1.8e-09 37.1 0.1 8.4e-05 22.2 0.0 3.6 3 0 0 3 3 3 2 TPR repeat TPR_7 PF13176.6 CDJ89418.1 - 3.1e-09 36.2 6.0 0.18 11.9 0.7 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ89418.1 - 1.2e-07 32.1 8.2 2.9 8.5 0.0 6.8 5 1 3 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ89418.1 - 3.1e-06 27.2 0.7 0.2 12.1 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ89418.1 - 0.00017 21.7 2.7 0.21 11.7 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ89418.1 - 0.001 19.5 15.3 0.028 15.1 1.9 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 CDJ89418.1 - 0.003 16.8 2.5 0.047 12.9 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC8 PF04049.13 CDJ89418.1 - 0.0056 16.7 1.6 0.046 13.8 0.0 2.7 3 0 0 3 3 3 1 Anaphase promoting complex subunit 8 / Cdc23 NARP1 PF12569.8 CDJ89418.1 - 0.0076 15.2 0.2 0.047 12.6 0.3 2.2 3 0 0 3 3 3 1 NMDA receptor-regulated protein 1 RPN7 PF10602.9 CDJ89418.1 - 0.13 11.9 2.0 11 5.7 0.8 2.5 1 1 1 2 2 2 0 26S proteasome subunit RPN7 ANAPC3 PF12895.7 CDJ89418.1 - 0.35 11.1 7.8 6.8 7.0 0.0 4.5 3 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CDJ89418.1 - 1 9.3 10.1 7.3 6.6 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Thioredoxin_8 PF13905.6 CDJ89419.1 - 1.7e-22 79.5 0.0 4.4e-21 75.0 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 CDJ89419.1 - 2.4e-05 24.1 0.0 5.9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CDJ89419.1 - 3e-05 23.9 0.0 6.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 CDJ89419.1 - 0.00047 20.1 0.1 0.16 12.0 0.2 2.7 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 CDJ89419.1 - 0.0015 18.9 0.0 0.017 15.5 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CDJ89419.1 - 0.021 14.6 0.0 0.16 11.7 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin ORF_12_N PF18042.1 CDJ89419.1 - 0.098 13.1 0.0 0.29 11.6 0.0 1.8 2 0 0 2 2 2 0 ORF 12 gene product N-terminal zf-CXXC PF02008.20 CDJ89420.1 - 1.3e-16 60.4 41.9 5.4e-12 45.5 21.0 2.4 2 0 0 2 2 2 2 CXXC zinc finger domain DUF3040 PF11239.8 CDJ89420.1 - 0.2 12.0 0.0 0.37 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Folate_carrier PF01770.18 CDJ89421.1 - 2e-127 425.4 25.3 2.5e-127 425.0 25.3 1.1 1 0 0 1 1 1 1 Reduced folate carrier MFS_1 PF07690.16 CDJ89421.1 - 7.4e-15 54.7 20.4 1.3e-13 50.6 20.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Folate_carrier PF01770.18 CDJ89422.1 - 8e-125 416.8 16.3 9.4e-125 416.6 16.3 1.0 1 0 0 1 1 1 1 Reduced folate carrier Pkinase_Tyr PF07714.17 CDJ89423.1 - 1.3e-35 122.9 0.0 1.3e-34 119.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ89423.1 - 3.5e-21 75.7 0.0 1.1e-20 74.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain F5_F8_type_C PF00754.25 CDJ89423.1 - 2.1e-16 60.2 0.1 1.7e-11 44.4 0.0 2.6 2 0 0 2 2 2 2 F5/8 type C domain Pentapeptide_3 PF13576.6 CDJ89423.1 - 0.056 13.6 0.4 0.49 10.6 0.0 2.6 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) MFS_1 PF07690.16 CDJ89424.1 - 3.1e-39 134.9 34.1 3.1e-39 134.9 34.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 CDJ89425.1 - 9.5e-38 130.0 15.3 9.5e-38 130.0 15.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CDJ89425.1 - 0.017 14.0 8.7 0.67 8.7 0.0 2.6 1 1 2 3 3 3 0 MFS_1 like family Collagen PF01391.18 CDJ89426.1 - 5.1e-14 51.8 127.1 9.7e-07 28.5 38.9 4.1 2 1 2 4 4 4 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ89426.1 - 9.9e-09 35.1 0.2 1.3e-08 34.8 0.2 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ89427.1 - 4.8e-21 74.3 125.9 2.5e-08 33.5 45.2 4.8 3 1 2 5 5 5 5 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ89427.1 - 1.4e-10 41.0 0.5 2e-10 40.6 0.5 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ89428.1 - 3.3e-22 78.0 90.3 4.7e-08 32.7 33.1 4.0 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ89428.1 - 4.4e-07 29.9 0.0 6.3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ89429.1 - 2.3e-13 49.7 135.4 3.3e-07 30.0 42.7 5.2 3 2 2 5 5 5 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ89429.1 - 7.1e-10 38.8 0.4 1.1e-09 38.2 0.4 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Col_cuticle_N PF01484.17 CDJ89430.1 - 1.7e-09 37.6 0.3 2.4e-09 37.1 0.3 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ89430.1 - 0.00077 19.2 155.7 2e+03 -1.4 65.2 5.5 2 1 1 3 3 3 0 Collagen triple helix repeat (20 copies) Neuralized PF07177.12 CDJ89431.1 - 3.8e-62 208.7 0.3 3.9e-49 166.5 0.1 2.4 2 0 0 2 2 2 2 Neuralized Chlorovi_GP_rpt PF06598.11 CDJ89431.1 - 0.4 10.8 2.5 0.29 11.2 0.2 2.0 2 0 0 2 2 2 0 Chlorovirus glycoprotein repeat RVT_1 PF00078.27 CDJ89432.1 - 1.6e-18 67.0 0.0 2.6e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CDJ89433.1 - 3.3e-08 33.3 0.0 5.9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Collagen PF01391.18 CDJ89434.1 - 1.7e-08 34.1 22.2 9.2e-08 31.7 22.2 2.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) DnaJ PF00226.31 CDJ89436.1 - 2.5e-16 59.5 2.3 2.5e-16 59.5 2.3 2.0 2 0 0 2 2 2 1 DnaJ domain ADIP PF11559.8 CDJ89437.1 - 0.058 13.5 11.2 0.083 13.0 11.2 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding LicD PF04991.13 CDJ89438.1 - 1.9 8.6 5.5 12 5.9 5.5 1.9 1 1 0 1 1 1 0 LicD family Ribophorin_II PF05817.14 CDJ89439.1 - 0.044 12.3 0.3 0.073 11.6 0.1 1.3 1 1 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II Asp-B-Hydro_N PF05279.11 CDJ89439.1 - 5.9 6.9 10.0 6.7 6.7 10.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region HTH_Tnp_Tc3_2 PF01498.18 CDJ89440.1 - 1.8e-23 82.6 4.2 2.3e-23 82.2 1.1 2.6 2 1 0 2 2 2 1 Transposase DDE_3 PF13358.6 CDJ89440.1 - 7e-18 64.8 0.0 1.5e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 CDJ89440.1 - 1.8e-08 34.9 8.4 1.3e-07 32.2 0.4 3.1 2 1 1 3 3 2 2 Homeodomain-like domain PAX PF00292.18 CDJ89440.1 - 2e-08 34.2 0.2 3.7e-08 33.4 0.2 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 CDJ89440.1 - 7.8e-07 28.7 0.8 0.00013 21.7 0.1 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 CDJ89440.1 - 1.1e-05 25.3 1.7 0.00022 21.2 0.2 2.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 CDJ89440.1 - 0.00024 21.2 0.4 0.022 14.9 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 CDJ89440.1 - 0.0011 18.8 2.8 0.35 10.8 0.2 2.5 2 0 0 2 2 2 2 MarR family CENP-B_N PF04218.13 CDJ89440.1 - 0.003 17.2 0.1 0.78 9.4 0.0 2.5 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_24 PF13412.6 CDJ89440.1 - 0.0034 16.9 2.9 1.7 8.3 1.0 3.3 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 CDJ89440.1 - 0.0049 16.5 1.1 0.33 10.6 0.1 2.9 3 1 0 3 3 2 1 Sigma-70, region 4 HTH_12 PF08461.10 CDJ89440.1 - 0.025 14.5 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain TrmB PF01978.19 CDJ89440.1 - 0.038 13.9 0.0 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_21 PF13276.6 CDJ89440.1 - 0.042 14.0 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 HTH-like domain Sigma70_r4 PF04545.16 CDJ89440.1 - 0.051 13.1 0.2 3.4 7.3 0.1 2.8 2 1 0 2 2 2 0 Sigma-70, region 4 GerE PF00196.19 CDJ89440.1 - 0.052 13.1 0.1 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_38 PF13936.6 CDJ89440.1 - 0.19 11.5 3.8 0.22 11.3 0.5 2.6 2 1 1 3 3 3 0 Helix-turn-helix domain HTH_11 PF08279.12 CDJ89440.1 - 1.9 8.5 3.8 12 5.9 0.6 3.2 2 2 1 3 3 3 0 HTH domain HTH_AsnC-type PF13404.6 CDJ89440.1 - 3.3 7.6 4.6 8 6.4 2.2 2.7 2 1 0 2 2 2 0 AsnC-type helix-turn-helix domain DNA_pol_phi PF04931.13 CDJ89441.1 - 0.0037 15.5 9.5 0.0038 15.4 9.5 1.1 1 0 0 1 1 1 1 DNA polymerase phi DUF262 PF03235.14 CDJ89441.1 - 0.19 11.9 4.7 0.25 11.5 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF2115 PF09888.9 CDJ89441.1 - 0.52 10.8 4.3 0.78 10.2 4.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) DUF2052 PF09747.9 CDJ89441.1 - 0.66 10.1 18.5 0.83 9.8 18.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CDC45 PF02724.14 CDJ89441.1 - 0.95 7.7 21.2 1 7.6 21.2 1.0 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 CDJ89441.1 - 1.4 8.1 8.2 1.9 7.6 8.2 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop53 PF07767.11 CDJ89441.1 - 1.7 7.9 32.1 2.3 7.5 32.1 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Pes-10 PF07149.11 CDJ89441.1 - 1.8 7.5 15.5 2.2 7.2 15.5 1.1 1 0 0 1 1 1 0 Pes-10 CDC27 PF09507.10 CDJ89441.1 - 2.6 7.4 17.1 3.1 7.1 17.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Vfa1 PF08432.10 CDJ89441.1 - 3.3 8.0 11.8 4.6 7.5 11.8 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Paf1 PF03985.13 CDJ89441.1 - 7.6 5.4 19.1 11 4.9 19.1 1.2 1 0 0 1 1 1 0 Paf1 DUF3854 PF12965.7 CDJ89442.1 - 0.028 14.4 0.2 0.052 13.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) DUF2207 PF09972.9 CDJ89442.1 - 0.59 8.8 6.4 0.97 8.1 6.0 1.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Rrn6 PF10214.9 CDJ89442.1 - 2.2 6.7 7.7 2.4 6.5 7.7 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CDC45 PF02724.14 CDJ89442.1 - 3.2 5.9 15.1 3.6 5.8 15.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 CDJ89442.1 - 5.1 6.4 24.8 7.4 5.9 24.8 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) EF-G-binding_N PF07299.11 CDJ89443.1 - 0.15 12.6 0.9 0.23 12.0 0.9 1.4 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal VSG_B PF13206.6 CDJ89443.1 - 1.8 7.7 7.8 2.3 7.4 7.8 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain CDC45 PF02724.14 CDJ89443.1 - 7.5 4.7 10.5 8.5 4.5 10.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RVT_1 PF00078.27 CDJ89444.1 - 1.2e-25 90.4 0.0 1.9e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Vault PF01505.18 CDJ89445.1 - 0.18 12.0 1.1 0.33 11.2 0.1 1.9 2 1 1 3 3 3 0 Major Vault Protein repeat domain TILa PF12714.7 CDJ89445.1 - 1.8 8.6 12.5 1.6 8.7 0.3 4.0 5 1 0 5 5 5 0 TILa domain zf-DBF PF07535.12 CDJ89447.1 - 2.9e-05 24.1 0.1 5.9e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 DBF zinc finger Cytochrom_B561 PF03188.16 CDJ89448.1 - 2.5e-42 144.3 7.9 3.9e-42 143.7 7.9 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Ion_trans_2 PF07885.16 CDJ89449.1 - 2e-31 107.8 19.0 3.1e-17 62.3 2.0 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 CDJ89449.1 - 1.7e-07 30.7 6.6 0.00016 21.0 0.0 2.5 2 1 1 3 3 3 2 Ion transport protein Lig_chan PF00060.26 CDJ89449.1 - 0.00015 21.6 0.0 0.01 15.7 0.0 2.2 2 0 0 2 2 2 2 Ligand-gated ion channel Peptidase_U4 PF03419.13 CDJ89449.1 - 0.81 8.9 7.2 0.14 11.4 3.4 1.5 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Kelch_1 PF01344.25 CDJ89452.1 - 8e-70 230.2 12.5 6.8e-15 54.4 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CDJ89452.1 - 3.7e-42 141.3 0.1 1.1e-06 28.6 0.0 6.4 2 2 4 6 6 6 6 Kelch motif BACK PF07707.15 CDJ89452.1 - 1.6e-31 108.4 0.6 1.6e-31 108.4 0.6 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 CDJ89452.1 - 4.5e-28 97.7 0.1 1e-27 96.6 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 CDJ89452.1 - 1e-26 91.9 2.5 4.1e-05 23.4 0.0 6.4 7 0 0 7 7 7 4 Kelch motif Kelch_4 PF13418.6 CDJ89452.1 - 2.4e-24 85.1 1.1 6.4e-05 22.9 0.0 6.4 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ89452.1 - 5.4e-15 55.3 4.2 0.19 12.0 0.1 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ89452.1 - 1.1e-10 41.2 3.7 0.00035 20.5 0.1 5.9 6 0 0 6 6 6 1 Kelch motif Kelch_1 PF01344.25 CDJ89453.1 - 6.6e-22 76.8 3.3 2.3e-12 46.3 0.0 3.9 3 1 1 4 4 4 3 Kelch motif Kelch_6 PF13964.6 CDJ89453.1 - 1.6e-11 44.0 0.8 8.8e-06 25.8 0.0 3.2 2 1 1 3 3 3 3 Kelch motif Kelch_2 PF07646.15 CDJ89453.1 - 5e-08 32.6 0.3 0.019 14.9 0.0 2.8 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CDJ89453.1 - 2.7e-05 24.1 0.1 0.00071 19.5 0.0 2.7 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ89453.1 - 0.00048 20.3 0.1 0.25 11.7 0.0 2.7 3 0 0 3 3 3 2 Galactose oxidase, central domain PQQ_3 PF13570.6 CDJ89453.1 - 0.064 13.8 1.1 4.6 7.8 0.1 2.7 3 0 0 3 3 3 0 PQQ-like domain Kelch_1 PF01344.25 CDJ89454.1 - 6.4e-18 64.1 0.0 4.9e-11 42.0 0.0 2.7 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 CDJ89454.1 - 5.9e-12 45.4 0.0 1.9e-08 34.3 0.0 2.3 1 1 1 2 2 2 2 Kelch motif Kelch_2 PF07646.15 CDJ89454.1 - 2.3e-05 24.2 0.1 0.0021 18.0 0.0 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.6 CDJ89454.1 - 0.00015 21.9 0.0 0.043 14.1 0.0 2.3 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_4 PF13418.6 CDJ89454.1 - 0.00019 21.3 0.0 0.9 9.6 0.0 2.7 2 1 0 2 2 2 2 Galactose oxidase, central domain DUF2370 PF10176.9 CDJ89454.1 - 0.024 14.3 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) rve PF00665.26 CDJ89456.1 - 6.3e-23 81.2 0.0 1.2e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CDJ89456.1 - 2.7e-13 49.9 0.0 4.5e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 CDJ89456.1 - 1.3e-06 28.0 0.0 2.8e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 CDJ89457.1 - 4.2e-10 40.0 0.0 3.9e-09 36.9 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ89457.1 - 1.3e-08 35.4 0.0 4.5e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 CDJ89457.1 - 0.0016 18.7 0.0 0.0035 17.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Ima1_N PF09779.9 CDJ89457.1 - 0.0051 17.7 6.4 0.013 16.3 6.4 1.7 1 0 0 1 1 1 1 Ima1 N-terminal domain Asp_protease PF09668.10 CDJ89457.1 - 0.024 14.4 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease HscB_4_cys PF18256.1 CDJ89457.1 - 0.13 12.1 9.6 0.3 11.0 9.6 1.6 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif zf-CCHC PF00098.23 CDJ89457.1 - 0.65 10.2 13.0 4.8 7.4 4.3 3.0 2 1 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 CDJ89458.1 - 1.1e-17 64.3 0.0 1.4e-17 64.0 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5126 PF17166.4 CDJ89458.1 - 0.089 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5126) Cadherin PF00028.17 CDJ89459.1 - 1.6e-44 150.2 0.3 1.6e-12 47.7 0.0 5.6 7 0 0 7 7 7 4 Cadherin domain Glyco_hydro2_C5 PF18565.1 CDJ89459.1 - 0.12 12.2 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 Glycoside hydrolase family 2 C-terminal domain 5 Oscp1 PF10188.9 CDJ89460.1 - 3e-57 193.6 9.7 4.7e-57 192.9 9.7 1.3 1 0 0 1 1 1 1 Organic solute transport protein 1 UPA_2 PF17809.1 CDJ89460.1 - 0.047 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 UPA domain TPR_22 PF18833.1 CDJ89460.1 - 0.76 10.0 3.9 0.37 11.0 0.7 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF5383 PF17355.2 CDJ89460.1 - 2 8.8 6.6 1.3 9.4 2.9 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5383) Cadherin PF00028.17 CDJ89461.1 - 8.1e-190 616.0 30.5 1.1e-20 73.9 0.4 19.3 20 0 0 20 20 20 17 Cadherin domain Cadherin_3 PF16184.5 CDJ89461.1 - 5.5e-15 55.3 20.3 0.041 13.9 0.0 10.5 9 1 1 10 10 10 5 Cadherin-like Cadherin_pro PF08758.11 CDJ89461.1 - 7e-14 51.8 0.0 0.015 15.4 0.0 10.0 11 0 0 11 11 11 3 Cadherin prodomain like Cadherin_2 PF08266.12 CDJ89461.1 - 8.6e-10 38.3 0.1 17 5.3 0.0 10.8 13 1 1 14 14 14 2 Cadherin-like Y_Y_Y PF07495.13 CDJ89461.1 - 0.032 14.2 1.1 4.9 7.2 0.0 5.0 5 0 0 5 5 5 0 Y_Y_Y domain Cadherin_4 PF17803.1 CDJ89461.1 - 0.033 14.8 0.0 0.033 14.8 0.0 10.4 9 1 0 9 9 9 0 Bacterial cadherin-like domain Astacin PF01400.24 CDJ89462.1 - 1e-53 181.8 0.0 1.9e-53 180.9 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Wzt_C PF14524.6 CDJ89462.1 - 6.8e-05 22.9 0.6 0.41 10.7 0.1 2.4 2 0 0 2 2 2 2 Wzt C-terminal domain Peptidase_M10 PF00413.24 CDJ89462.1 - 0.00096 19.0 0.1 0.059 13.2 0.1 2.3 1 1 1 2 2 2 1 Matrixin Reprolysin_4 PF13583.6 CDJ89462.1 - 0.0044 16.7 0.0 0.008 15.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DP-EP PF08985.11 CDJ89462.1 - 0.017 15.3 0.1 8 6.7 0.0 2.3 2 0 0 2 2 2 0 DP-EP family DUF5123 PF17161.4 CDJ89462.1 - 8.3 7.5 8.1 35 5.5 1.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5123) Astacin PF01400.24 CDJ89463.1 - 4.7e-33 114.4 0.0 8.7e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 CDJ89463.1 - 0.00043 20.2 0.1 0.041 13.7 0.1 2.2 1 1 1 2 2 2 1 Matrixin Reprolysin_4 PF13583.6 CDJ89463.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CDJ89463.1 - 0.11 12.7 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF4953 PF16313.5 CDJ89463.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Met-zincin ShK PF01549.24 CDJ89463.1 - 0.15 12.6 6.5 0.34 11.5 6.5 1.6 1 0 0 1 1 1 0 ShK domain-like Astacin PF01400.24 CDJ89464.1 - 0.00036 20.2 0.0 0.0005 19.7 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Pyr_redox_2 PF07992.14 CDJ89465.1 - 3.3e-18 66.0 0.0 2.3e-11 43.5 0.0 2.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ89465.1 - 2.1e-05 23.4 0.0 0.0034 16.1 0.0 2.8 2 1 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 CDJ89465.1 - 0.0006 19.0 0.0 0.0053 15.9 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 CDJ89465.1 - 0.0011 18.3 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 CDJ89465.1 - 0.0018 18.3 0.0 2.3 8.2 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 CDJ89465.1 - 0.0088 15.7 0.0 0.31 10.6 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CDJ89465.1 - 0.0092 15.1 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 CDJ89465.1 - 0.014 14.5 0.1 1.8 7.6 0.0 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 CDJ89465.1 - 0.015 15.5 0.0 0.037 14.2 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CDJ89465.1 - 0.023 14.0 0.0 4.3 6.5 0.0 2.8 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L37e PF01907.19 CDJ89466.1 - 0.69 10.1 2.9 1.2 9.4 2.9 1.3 1 0 0 1 1 1 0 Ribosomal protein L37e PE-PPE PF08237.11 CDJ89468.1 - 0.18 11.3 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 PE-PPE domain MFS_1 PF07690.16 CDJ89470.1 - 3.9e-12 45.8 27.0 3.9e-12 45.8 27.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_2_3 PF16080.5 CDJ89470.1 - 0.13 12.0 1.2 0.59 9.9 0.0 2.8 3 0 0 3 3 3 0 Bacteriophage holin family HP1 Ank PF00023.30 CDJ89471.1 - 0.00017 21.9 0.5 0.13 12.8 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 CDJ89471.1 - 0.0079 16.8 0.0 0.023 15.3 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ89471.1 - 0.15 12.6 0.0 0.3 11.7 0.0 1.7 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ89472.1 - 0.00017 21.9 0.5 0.13 12.8 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 CDJ89472.1 - 0.0079 16.8 0.0 0.023 15.3 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ89472.1 - 0.15 12.6 0.0 0.3 11.7 0.0 1.7 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ89473.1 - 0.00017 21.9 0.5 0.13 12.8 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 CDJ89473.1 - 0.0079 16.8 0.0 0.023 15.3 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ89473.1 - 0.15 12.6 0.0 0.3 11.7 0.0 1.7 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) WW PF00397.26 CDJ89474.1 - 1.6e-08 34.5 8.9 4.7e-08 33.0 0.4 2.7 2 0 0 2 2 2 1 WW domain PDZ_6 PF17820.1 CDJ89474.1 - 3.8e-08 33.0 0.2 1.1e-07 31.6 0.2 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CDJ89474.1 - 4e-08 33.5 0.0 9.8e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain FERM_M PF00373.18 CDJ89474.1 - 1.4e-06 28.7 0.4 8.1e-06 26.2 0.1 2.3 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.10 CDJ89474.1 - 4.3e-06 26.6 0.0 4.6e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 FERM N-terminal domain FERM_f0 PF16511.5 CDJ89474.1 - 0.0008 19.7 0.0 0.013 15.8 0.0 2.4 2 0 0 2 2 2 1 N-terminal or F0 domain of Talin-head FERM RA PF00788.23 CDJ89474.1 - 0.0021 18.7 0.0 0.0048 17.5 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain FERM_N_2 PF18038.1 CDJ89474.1 - 0.0029 18.4 0.1 0.059 14.2 0.0 3.0 3 0 0 3 3 3 1 FERM N-terminal domain PDZ_2 PF13180.6 CDJ89474.1 - 0.026 14.8 0.1 0.09 13.1 0.1 1.9 1 0 0 1 1 1 0 PDZ domain RBD PF02196.15 CDJ89474.1 - 0.064 13.3 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 Raf-like Ras-binding domain MCM PF00493.23 CDJ89475.1 - 1.8e-99 331.4 0.0 2.7e-99 330.8 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CDJ89475.1 - 1e-30 106.2 0.0 1.9e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CDJ89475.1 - 3e-23 82.1 0.8 6.6e-23 80.9 0.8 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 CDJ89475.1 - 2.3e-07 30.4 0.0 1e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 CDJ89475.1 - 1.6e-05 25.4 0.0 4.4e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 CDJ89475.1 - 0.0017 18.4 0.0 0.0044 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CDJ89475.1 - 0.0021 17.9 0.0 0.0071 16.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CDJ89475.1 - 0.02 14.6 0.0 0.076 12.7 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain RcpC PF16976.5 CDJ89475.1 - 0.023 14.8 0.0 0.071 13.2 0.0 1.9 1 0 0 1 1 1 0 Flp pilus assembly protein RcpC/CpaB MCM_bind PF09739.9 CDJ89475.1 - 0.6 8.5 3.3 1.1 7.6 0.2 2.3 3 0 0 3 3 3 0 Mini-chromosome maintenance replisome factor Y_phosphatase PF00102.27 CDJ89476.1 - 7.6e-63 212.2 0.0 9.5e-63 211.9 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CDJ89476.1 - 0.0021 18.0 0.2 0.005 16.8 0.1 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 CDJ89476.1 - 0.02 14.7 0.9 0.052 13.4 0.9 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Ank PF00023.30 CDJ89477.1 - 0.00017 21.9 0.5 0.13 12.8 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 CDJ89477.1 - 0.0079 16.8 0.0 0.023 15.3 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ89477.1 - 0.15 12.6 0.0 0.3 11.7 0.0 1.7 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) DUF851 PF05867.11 CDJ89478.1 - 3.2e-05 23.5 0.0 3.2e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF851) Exo_endo_phos PF03372.23 CDJ89479.1 - 1.3e-21 77.2 0.1 1.8e-21 76.7 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1385 PF07136.11 CDJ89479.1 - 0.21 10.8 1.0 0.32 10.3 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) PrgI PF12666.7 CDJ89479.1 - 0.33 11.7 4.6 0.66 10.7 4.6 1.4 1 0 0 1 1 1 0 PrgI family protein DUF1275 PF06912.11 CDJ89480.1 - 0.0013 18.7 5.1 0.0013 18.7 5.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1275) T_hemolysin PF12261.8 CDJ89480.1 - 0.035 13.8 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Thermostable hemolysin MTABC_N PF16185.5 CDJ89480.1 - 0.12 11.8 4.9 0.21 11.1 4.9 1.2 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region TMEM52 PF14979.6 CDJ89480.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Transmembrane 52 DUF3021 PF11457.8 CDJ89480.1 - 2.4 8.5 14.7 0.88 9.9 11.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3021) MPP6 PF10175.9 CDJ89481.1 - 1.2e-07 32.2 6.5 2e-07 31.5 6.4 1.4 1 1 0 1 1 1 1 M-phase phosphoprotein 6 NUC173 PF08161.12 CDJ89482.1 - 2.5e-50 171.0 0.3 2e-49 168.0 0.0 2.7 2 0 0 2 2 2 1 NUC173 domain CAS_CSE1 PF03378.15 CDJ89482.1 - 0.2 10.1 1.1 1.1 7.7 0.0 2.7 3 0 0 3 3 3 0 CAS/CSE protein, C-terminus Ipi1_N PF12333.8 CDJ89482.1 - 0.23 12.1 3.0 32 5.2 0.0 4.1 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation Adaptin_N PF01602.20 CDJ89482.1 - 1.1 7.8 7.8 19 3.6 0.1 3.9 3 1 0 4 4 4 0 Adaptin N terminal region bZIP_1 PF00170.21 CDJ89483.1 - 2.6e-09 37.0 11.2 4.5e-09 36.3 11.2 1.4 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 CDJ89483.1 - 3e-06 27.7 6.5 3.4e-06 27.5 6.5 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 CDJ89483.1 - 6.6e-05 22.9 15.8 0.00085 19.4 5.8 2.3 1 1 1 2 2 2 2 Basic region leucine zipper Rx_N PF18052.1 CDJ89483.1 - 0.0024 18.1 0.7 0.0024 18.1 0.7 1.5 2 0 0 2 2 2 1 Rx N-terminal domain Fib_alpha PF08702.10 CDJ89483.1 - 0.0077 16.4 1.9 0.0084 16.3 1.9 1.0 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Mto2_bdg PF12808.7 CDJ89483.1 - 0.12 12.7 8.0 3.3 8.1 0.4 2.7 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF829 PF05705.14 CDJ89484.1 - 1.5e-29 103.6 0.4 1.7e-29 103.4 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) MOZ_SAS PF01853.18 CDJ89485.1 - 2.8e-12 46.7 0.3 6e-12 45.6 0.0 1.7 2 0 0 2 2 2 1 MOZ/SAS family zf-MYST PF17772.1 CDJ89485.1 - 2.3e-08 33.5 0.6 2.3e-08 33.5 0.6 3.3 3 1 0 3 3 3 2 MYST family zinc finger domain PHD PF00628.29 CDJ89485.1 - 0.00029 20.7 10.1 0.00029 20.7 10.1 3.5 2 2 1 3 3 3 2 PHD-finger zf-C2H2 PF00096.26 CDJ89485.1 - 0.07 13.6 0.4 0.07 13.6 0.4 4.2 4 1 0 4 4 4 0 Zinc finger, C2H2 type MOZ_SAS PF01853.18 CDJ89486.1 - 7.4e-38 130.0 0.1 9.3e-38 129.7 0.1 1.1 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_16 PF05301.11 CDJ89486.1 - 0.066 13.0 0.0 0.093 12.5 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 WD40 PF00400.32 CDJ89487.1 - 1.9e-08 34.8 12.5 0.0032 18.3 0.7 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat F-box-like PF12937.7 CDJ89487.1 - 2e-07 30.8 1.8 4.3e-07 29.7 1.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDJ89487.1 - 0.0013 18.6 1.8 0.0031 17.4 1.0 2.1 2 0 0 2 2 2 1 F-box domain PQQ_3 PF13570.6 CDJ89487.1 - 0.036 14.6 0.1 14 6.3 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain PI-PLC-X PF00388.19 CDJ89489.1 - 1.2e-55 187.1 0.1 2.5e-55 186.1 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CDJ89489.1 - 6.1e-40 136.1 0.4 1.9e-39 134.6 0.1 2.1 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain SH2 PF00017.24 CDJ89489.1 - 5.4e-34 116.1 1.5 1.2e-17 63.8 0.5 2.8 2 0 0 2 2 2 2 SH2 domain C2 PF00168.30 CDJ89489.1 - 1.7e-18 66.8 0.0 5.9e-18 65.1 0.0 2.0 1 0 0 1 1 1 1 C2 domain SH3_9 PF14604.6 CDJ89489.1 - 1.8e-07 30.9 0.0 3.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDJ89489.1 - 1.1e-06 28.1 0.0 2.9e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 CDJ89489.1 - 5.6e-06 26.8 1.5 0.043 14.3 0.1 3.6 3 0 0 3 3 3 1 PH domain SH3_2 PF07653.17 CDJ89489.1 - 1.3e-05 24.8 0.0 3.1e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Cpn60_TCP1 PF00118.24 CDJ89490.1 - 4.3e-140 467.6 12.9 5e-140 467.4 12.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Apolipoprotein PF01442.18 CDJ89492.1 - 1.9e-06 27.9 2.7 5.1e-05 23.2 2.8 2.1 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 CDJ89492.1 - 8.1e-05 23.2 16.6 0.19 12.4 1.4 4.1 1 1 3 4 4 4 3 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 CDJ89492.1 - 0.00022 21.3 2.3 0.0037 17.4 2.1 2.6 1 1 2 3 3 3 2 Apolipophorin-III precursor (apoLp-III) MT0933_antitox PF14013.6 CDJ89492.1 - 0.0037 17.5 1.5 0.0037 17.5 1.5 5.2 3 1 2 5 5 5 2 MT0933-like antitoxin protein Perilipin PF03036.16 CDJ89492.1 - 0.017 14.2 6.9 0.15 11.0 0.1 2.4 1 1 0 2 2 2 0 Perilipin family ApoO PF09769.9 CDJ89492.1 - 0.034 14.1 0.5 2.4 8.1 0.1 3.2 2 1 1 3 3 3 0 Apolipoprotein O DUF2884 PF11101.8 CDJ89492.1 - 0.087 12.3 2.9 0.16 11.4 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) Phasin PF05597.11 CDJ89492.1 - 0.12 12.3 9.2 8.4 6.4 1.5 3.7 1 1 2 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF2203 PF09969.9 CDJ89492.1 - 0.21 12.3 2.4 8.2 7.2 0.3 3.2 1 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) TPR_MLP1_2 PF07926.12 CDJ89492.1 - 0.29 11.2 1.4 0.44 10.6 0.1 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1451 PF07295.11 CDJ89492.1 - 0.51 10.4 2.5 11 6.0 0.8 2.7 1 1 0 2 2 2 0 Zinc-ribbon containing domain Chlorosome_CsmC PF11098.8 CDJ89492.1 - 0.71 9.9 29.3 0.94 9.5 9.3 3.9 1 1 3 4 4 4 0 Chlorosome envelope protein C DAGK_prokar PF01219.19 CDJ89492.1 - 2.6 7.9 5.9 1.7 8.5 0.1 3.3 2 1 1 3 3 3 0 Prokaryotic diacylglycerol kinase HSP9_HSP12 PF04119.12 CDJ89492.1 - 3.6 8.1 6.3 71 3.9 0.0 4.3 4 3 3 7 7 7 0 Heat shock protein 9/12 ISG65-75 PF11727.8 CDJ89492.1 - 6.2 6.0 21.9 0.097 11.9 4.6 2.7 1 1 2 3 3 3 0 Invariant surface glycoprotein REF PF05755.12 CDJ89492.1 - 6.7 6.5 9.1 1.5 8.6 2.8 2.4 1 1 1 2 2 2 0 Rubber elongation factor protein (REF) I-set PF07679.16 CDJ89493.1 - 4.2e-05 23.5 0.1 0.00011 22.2 0.1 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ89493.1 - 6e-05 23.6 0.0 9.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CDJ89493.1 - 0.0053 16.9 0.0 0.0073 16.5 0.0 1.3 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CDJ89493.1 - 0.011 16.1 0.0 0.018 15.4 0.0 1.4 1 1 0 1 1 1 0 Immunoglobulin domain Peptidase_C13 PF01650.18 CDJ89494.1 - 1.1e-24 87.4 0.2 1.4e-24 87.0 0.2 1.0 1 0 0 1 1 1 1 Peptidase C13 family LSM PF01423.22 CDJ89496.1 - 3.1e-16 58.8 0.5 4.1e-16 58.4 0.5 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CDJ89496.1 - 0.0076 15.9 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Hfq protein RVT_1 PF00078.27 CDJ89499.1 - 3.1e-07 30.2 0.0 5.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GIY-YIG PF01541.24 CDJ89499.1 - 0.02 15.2 0.0 0.2 12.0 0.0 2.4 2 0 0 2 2 2 0 GIY-YIG catalytic domain MCD_N PF17408.2 CDJ89500.1 - 5.6e-16 58.4 0.0 1.7e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase N-terminal domain Glyco_hydro_63 PF03200.16 CDJ89501.1 - 5e-192 639.0 2.7 5.6e-155 516.8 1.0 2.4 2 1 1 3 3 3 2 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 CDJ89501.1 - 4.6e-24 85.8 1.2 8.7e-24 84.9 1.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain UDPGT PF00201.18 CDJ89503.1 - 1.4e-130 436.5 0.0 3.4e-69 234.0 0.0 2.0 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ89503.1 - 9.1e-32 110.3 0.0 1.8e-14 54.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 CDJ89503.1 - 1e-09 38.1 0.0 0.00012 21.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 1 Glyco_trans_1_4 PF13692.6 CDJ89503.1 - 0.0029 18.0 0.0 3.7 8.0 0.0 2.8 2 0 0 2 2 2 2 Glycosyl transferases group 1 Tombus_P33 PF08500.10 CDJ89503.1 - 0.0054 16.7 2.3 0.14 12.1 0.3 2.3 2 0 0 2 2 2 1 Tombusvirus p33 Glyco_transf_4 PF13439.6 CDJ89503.1 - 0.06 13.3 0.1 15 5.6 0.0 2.9 3 0 0 3 3 3 0 Glycosyltransferase Family 4 MazG_C PF18722.1 CDJ89503.1 - 0.11 12.0 0.2 13 5.3 0.0 2.7 3 0 0 3 3 3 0 MazG C-terminal domain Glyco_trans_4_2 PF13477.6 CDJ89503.1 - 0.14 12.2 0.2 20 5.2 0.0 3.2 3 0 0 3 3 3 0 Glycosyl transferase 4-like Tmpp129 PF10272.9 CDJ89503.1 - 0.73 9.1 3.0 15 4.8 0.8 2.3 2 0 0 2 2 2 0 Putative transmembrane protein precursor UDPGT PF00201.18 CDJ89504.1 - 5.5e-63 213.5 0.0 6.9e-63 213.2 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ89504.1 - 4.4e-13 49.5 0.0 7.5e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 CDJ89504.1 - 4.7e-05 22.8 0.0 8.8e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 1 Acyl-CoA_dh_2 PF08028.11 CDJ89505.1 - 0.0017 18.6 0.8 0.0017 18.6 0.8 3.9 1 1 3 4 4 4 1 Acyl-CoA dehydrogenase, C-terminal domain RPAP1_C PF08620.10 CDJ89505.1 - 3.4 7.9 6.1 0.72 10.0 1.8 2.1 2 0 0 2 2 2 0 RPAP1-like, C-terminal TDP43_N PF18694.1 CDJ89507.1 - 1.9e-25 88.5 0.0 3.2e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain RRM_1 PF00076.22 CDJ89507.1 - 1.7e-20 72.6 3.0 2.5e-09 36.8 0.2 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L_HMGIC_fpl PF10242.9 CDJ89508.1 - 0.0011 19.3 5.7 0.0014 18.8 5.7 1.1 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Phage_holin_3_6 PF07332.11 CDJ89508.1 - 0.0012 18.8 6.5 0.0016 18.4 6.5 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF3185 PF11381.8 CDJ89508.1 - 0.018 15.0 3.6 0.19 11.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF2206 PF09971.9 CDJ89508.1 - 0.029 13.2 0.1 0.033 12.9 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Transglut_prok PF09017.10 CDJ89508.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Microbial transglutaminase DUF2207 PF09972.9 CDJ89508.1 - 1.8 7.2 5.7 2.2 6.9 5.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF423 PF04241.15 CDJ89508.1 - 2.2 8.6 6.1 5 7.4 4.9 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF423) DUF973 PF06157.11 CDJ89508.1 - 3.1 6.8 8.2 4.2 6.3 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF3742 PF12553.8 CDJ89508.1 - 3.8 7.6 4.4 1.2 9.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3742) DUF2721 PF11026.8 CDJ89508.1 - 6.2 6.7 9.0 9.1 6.2 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Tetraspanin PF00335.20 CDJ89508.1 - 9.7 5.8 10.3 50 3.5 10.3 1.8 1 1 0 1 1 1 0 Tetraspanin family DUF5386 PF17360.2 CDJ89509.1 - 2.6e-13 50.2 1.2 3.4e-08 33.6 0.1 2.2 1 1 1 2 2 2 2 Family of unknown function (DUF5386) HTH_50 PF18024.1 CDJ89510.1 - 0.04 13.5 0.1 0.065 12.9 0.1 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 CDJ89510.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF190 PF02641.15 CDJ89510.1 - 0.11 12.9 0.0 0.13 12.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized ACR, COG1993 Guanylate_cyc PF00211.20 CDJ89511.1 - 2.9e-62 209.6 0.0 4.1e-62 209.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 CDJ89511.1 - 1e-05 25.1 0.7 1.9e-05 24.2 0.7 1.4 1 0 0 1 1 1 1 Heme NO binding associated dsDNA_bind PF01984.20 CDJ89511.1 - 0.0086 16.3 0.1 0.019 15.3 0.0 1.5 2 0 0 2 2 2 1 Double-stranded DNA-binding domain 7TM_GPCR_Srab PF10292.9 CDJ89512.1 - 3e-11 42.8 7.6 3e-11 42.8 7.6 2.3 1 1 1 2 2 2 2 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Srb PF02175.16 CDJ89512.1 - 1.9e-10 40.9 1.6 1.9e-10 40.9 1.6 2.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srb 7TM_GPCR_Sra PF02117.16 CDJ89512.1 - 1.9e-07 30.2 10.8 1.9e-07 30.2 10.8 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Sra DUF1761 PF08570.10 CDJ89512.1 - 0.1 12.9 8.8 0.33 11.2 0.5 2.9 2 2 1 3 3 3 0 Protein of unknown function (DUF1761) DUF983 PF06170.12 CDJ89512.1 - 0.65 10.4 5.1 9.1 6.8 0.7 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF983) DUF4305 PF14146.6 CDJ89512.1 - 2.6 8.3 7.9 7.9 6.8 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4305) 7TM_GPCR_Srb PF02175.16 CDJ89513.1 - 8.4e-11 42.1 2.2 9.7e-11 41.9 2.2 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srb 7TM_GPCR_Srab PF10292.9 CDJ89513.1 - 2.4e-08 33.3 1.5 2.7e-08 33.1 1.5 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor Sre PF03125.18 CDJ89513.1 - 3.3e-05 23.2 2.1 3.3e-05 23.2 2.1 1.7 1 1 1 2 2 2 1 C. elegans Sre G protein-coupled chemoreceptor 7TM_GPCR_Sra PF02117.16 CDJ89513.1 - 0.014 14.3 1.0 0.016 14.1 1.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sra 7tm_1 PF00001.21 CDJ89513.1 - 0.39 10.0 3.7 0.67 9.2 3.7 1.4 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srab PF10292.9 CDJ89514.1 - 2.4e-11 43.1 2.1 1.4e-09 37.3 0.3 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Srb PF02175.16 CDJ89514.1 - 4.7e-07 29.8 3.5 9.6e-06 25.5 0.2 2.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srb zf-C2H2_2 PF12756.7 CDJ89516.1 - 0.0042 17.4 0.1 0.0058 16.9 0.1 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 CDJ89516.1 - 0.011 16.1 0.5 0.032 14.7 0.5 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 CDJ89516.1 - 0.065 13.5 0.6 0.1 12.9 0.6 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding CX PF01705.19 CDJ89517.1 - 1e-05 25.9 1.4 1e-05 25.9 1.4 3.2 3 0 0 3 3 3 2 CX module 7TM_GPCR_Srv PF10323.9 CDJ89518.1 - 1.9e-14 53.7 2.0 2.1e-14 53.6 2.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 CDJ89518.1 - 5.4e-07 29.5 5.1 6.5e-07 29.2 5.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 CDJ89518.1 - 4.6e-06 26.1 2.8 5.1e-06 26.0 2.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Srg PF02118.21 CDJ89518.1 - 9.4e-06 25.5 6.3 2e-05 24.4 6.3 1.5 1 1 0 1 1 1 1 Srg family chemoreceptor MgtE PF01769.16 CDJ89518.1 - 0.54 10.6 4.5 0.71 10.3 4.0 1.5 1 1 0 1 1 1 0 Divalent cation transporter ANF_receptor PF01094.28 CDJ89519.1 - 2.2e-07 30.3 0.0 2.6e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peptidase_C1 PF00112.23 CDJ89520.1 - 9e-39 133.8 3.2 1.3e-38 133.3 3.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Paramyxo_P_V_N PF13825.6 CDJ89520.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus Med11 PF10280.9 CDJ89521.1 - 0.00027 21.4 0.2 0.00029 21.3 0.2 1.2 1 0 0 1 1 1 1 Mediator complex protein Neur_chan_LBD PF02931.23 CDJ89523.1 - 3e-43 147.8 1.3 3e-43 147.8 1.3 1.5 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ89523.1 - 2.2e-10 41.0 6.2 1.3e-07 31.9 4.3 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Phage_Gp23 PF10669.9 CDJ89523.1 - 0.25 11.7 0.1 0.25 11.7 0.1 2.1 2 1 0 2 2 2 0 Protein gp23 (Bacteriophage A118) WD40 PF00400.32 CDJ89524.1 - 4.5e-18 65.3 4.7 1.3e-06 29.0 0.0 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ89524.1 - 2.1e-05 24.8 0.0 2.6 8.4 0.0 5.4 1 1 5 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CDJ89524.1 - 0.1 13.1 1.1 2.6 8.6 0.1 3.5 3 1 0 3 3 3 0 PQQ-like domain Cnd3 PF12719.7 CDJ89525.1 - 6.8e-26 91.1 2.1 6.8e-26 91.1 2.1 2.0 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 CDJ89525.1 - 3.7e-06 27.2 0.2 0.26 11.7 0.0 4.0 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.22 CDJ89525.1 - 0.021 15.0 1.9 0.43 11.0 0.1 4.0 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 CDJ89525.1 - 0.04 14.4 0.2 0.49 11.0 0.1 2.9 2 0 0 2 2 2 0 HEAT-like repeat Ribosom_S12_S23 PF00164.25 CDJ89526.1 - 2.7e-21 75.3 0.2 3.2e-21 75.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 NTP_transf_2 PF01909.23 CDJ89528.1 - 0.00085 19.6 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 CDJ89528.1 - 0.082 13.1 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CDJ89529.1 - 6.7e-05 23.1 0.0 0.00017 21.8 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CDJ89529.1 - 0.002 18.2 0.1 0.011 15.8 0.0 2.2 1 1 1 2 2 2 1 Polymerase beta, Nucleotidyltransferase DUF4269 PF14091.6 CDJ89529.1 - 0.0025 18.1 0.0 0.005 17.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4269) Med24_N PF11277.8 CDJ89530.1 - 7.4e-36 123.6 15.7 1e-35 123.2 15.7 1.1 1 0 0 1 1 1 1 Mediator complex subunit 24 N-terminal Linker_histone PF00538.19 CDJ89531.1 - 0.007 16.7 0.1 0.007 16.7 0.1 1.7 2 0 0 2 2 2 1 linker histone H1 and H5 family Ground-like PF04155.18 CDJ89532.1 - 1.7e-10 41.4 1.0 2.3e-10 41.0 1.0 1.2 1 0 0 1 1 1 1 Ground-like domain PqqD PF05402.12 CDJ89533.1 - 0.14 12.5 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) Pkinase PF00069.25 CDJ89534.1 - 3.3e-40 138.1 0.1 4e-40 137.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ89534.1 - 2.4e-27 95.8 0.0 3.3e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ89534.1 - 0.0056 16.0 0.0 0.0069 15.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CDJ89534.1 - 0.065 12.8 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 RIO1 family G6PD_C PF02781.16 CDJ89535.1 - 5.2e-113 377.1 0.0 6.6e-113 376.7 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CDJ89535.1 - 8.9e-63 212.1 0.1 1.9e-62 211.1 0.0 1.6 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain SRP_TPR_like PF17004.5 CDJ89535.1 - 0.053 13.5 0.5 0.13 12.3 0.5 1.6 1 0 0 1 1 1 0 Putative TPR-like repeat DUF150 PF02576.17 CDJ89535.1 - 0.14 12.5 0.0 3.3 8.2 0.0 2.4 2 0 0 2 2 2 0 RimP N-terminal domain Prefoldin_2 PF01920.20 CDJ89536.1 - 1.2e-24 86.3 9.3 1.3e-24 86.1 9.3 1.0 1 0 0 1 1 1 1 Prefoldin subunit LXG PF04740.12 CDJ89536.1 - 0.00013 21.7 8.9 0.0067 16.2 1.3 2.1 2 0 0 2 2 2 2 LXG domain of WXG superfamily Cnn_1N PF07989.11 CDJ89536.1 - 0.00056 20.0 5.6 0.0036 17.4 0.7 2.2 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 Syntaxin PF00804.25 CDJ89536.1 - 0.0021 17.8 3.0 0.0028 17.4 3.0 1.2 1 0 0 1 1 1 1 Syntaxin HMMR_N PF15905.5 CDJ89536.1 - 0.0063 16.0 8.5 0.0079 15.7 8.5 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal DUF5595 PF18077.1 CDJ89536.1 - 0.013 15.6 6.7 0.023 14.8 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) DASH_Dad3 PF08656.10 CDJ89536.1 - 0.018 15.1 1.3 0.018 15.1 1.3 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad3 Snapin_Pallidin PF14712.6 CDJ89536.1 - 0.019 15.4 4.9 0.66 10.4 0.8 2.2 2 0 0 2 2 2 0 Snapin/Pallidin Fungal_TACC PF12709.7 CDJ89536.1 - 0.021 15.3 8.0 0.12 12.8 0.6 2.3 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins MHC_I PF00129.18 CDJ89536.1 - 0.033 13.7 0.1 0.052 13.1 0.1 1.2 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 DivIC PF04977.15 CDJ89536.1 - 0.034 13.9 11.5 0.15 11.8 2.7 2.3 2 0 0 2 2 2 0 Septum formation initiator Rx_N PF18052.1 CDJ89536.1 - 0.037 14.3 2.8 0.25 11.6 0.4 2.2 2 0 0 2 2 2 0 Rx N-terminal domain FliD_N PF02465.18 CDJ89536.1 - 0.049 14.3 4.2 4.7 8.0 0.8 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF2935 PF11155.8 CDJ89536.1 - 0.05 13.9 2.0 0.064 13.6 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) DUF724 PF05266.14 CDJ89536.1 - 0.062 13.1 6.3 0.086 12.7 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) KxDL PF10241.9 CDJ89536.1 - 0.082 13.2 4.6 3.6 7.9 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein RPW8 PF05659.11 CDJ89536.1 - 0.14 11.9 3.4 0.61 9.8 0.3 2.1 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Occludin_ELL PF07303.13 CDJ89536.1 - 0.15 12.8 5.5 0.81 10.4 0.2 2.1 1 1 1 2 2 2 0 Occludin homology domain WXG100 PF06013.12 CDJ89536.1 - 0.16 12.2 4.1 1.2 9.4 0.4 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF465 PF04325.13 CDJ89536.1 - 0.18 11.8 6.2 0.21 11.7 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF465) DUF4446 PF14584.6 CDJ89536.1 - 0.19 11.7 3.3 2 8.4 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) FlaC_arch PF05377.11 CDJ89536.1 - 0.28 11.6 10.6 1.7 9.1 1.7 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3854 PF12965.7 CDJ89536.1 - 0.28 11.2 1.8 2.3 8.2 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3854) SlyX PF04102.12 CDJ89536.1 - 0.29 11.8 5.3 1.1 9.9 0.3 2.3 2 0 0 2 2 2 0 SlyX NPV_P10 PF05531.12 CDJ89536.1 - 0.36 11.3 4.2 1.4 9.4 1.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Rho_Binding PF08912.11 CDJ89536.1 - 0.42 11.4 9.6 1.1 10.1 1.9 2.3 2 0 0 2 2 2 0 Rho Binding GrpE PF01025.19 CDJ89536.1 - 0.44 10.2 12.8 3.1e+02 0.9 12.8 2.1 1 1 0 1 1 1 0 GrpE DUF1664 PF07889.12 CDJ89536.1 - 0.59 10.2 5.8 3.2 7.8 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Tup_N PF08581.10 CDJ89536.1 - 1.1 9.6 9.3 3.4 8.0 0.7 2.7 2 1 0 2 2 2 0 Tup N-terminal Swi5 PF07061.11 CDJ89536.1 - 1.1 9.4 7.5 4.6 7.4 1.0 2.3 2 0 0 2 2 2 0 Swi5 Baculo_PEP_C PF04513.12 CDJ89536.1 - 1.2 9.1 8.0 6.4 6.8 8.0 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TolA_bind_tri PF16331.5 CDJ89536.1 - 1.3 9.2 7.8 2.1 8.5 1.4 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation YabA PF06156.13 CDJ89536.1 - 1.3 9.7 11.9 14 6.4 2.5 2.1 1 1 1 2 2 2 0 Initiation control protein YabA OmpH PF03938.14 CDJ89536.1 - 1.3 9.4 11.1 14 6.0 11.1 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) zf-C4H2 PF10146.9 CDJ89536.1 - 1.3 9.3 6.8 1.8 8.9 6.8 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein DCB PF16213.5 CDJ89536.1 - 1.4 8.5 5.7 1 9.0 1.6 2.0 1 1 1 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 Fib_alpha PF08702.10 CDJ89536.1 - 1.5 9.0 8.2 2.4 8.3 8.3 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family ACCA PF03255.14 CDJ89536.1 - 1.5 8.6 5.5 1.2 8.9 0.9 2.0 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit FlxA PF14282.6 CDJ89536.1 - 1.7 8.7 11.0 1.8 8.6 0.9 2.1 2 0 0 2 2 2 0 FlxA-like protein bZIP_1 PF00170.21 CDJ89536.1 - 1.8 8.7 11.5 5.9 7.1 0.8 2.5 2 1 0 2 2 2 0 bZIP transcription factor Prefoldin PF02996.17 CDJ89536.1 - 2 8.4 11.3 1.5 8.7 1.1 2.2 1 1 0 2 2 2 0 Prefoldin subunit CENP-H PF05837.12 CDJ89536.1 - 2.1 8.8 9.9 15 6.0 9.9 1.9 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Ribosomal_L29 PF00831.23 CDJ89536.1 - 2.3 8.2 8.3 7.1 6.7 0.3 2.6 2 1 1 3 3 3 0 Ribosomal L29 protein DASH_Dad4 PF08650.10 CDJ89536.1 - 3.4 7.7 7.9 0.55 10.2 1.4 2.2 2 1 0 2 2 2 0 DASH complex subunit Dad4 SseC PF04888.12 CDJ89536.1 - 4.4 6.8 8.7 1.8 8.1 2.1 2.0 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family Spc24 PF08286.11 CDJ89536.1 - 4.6 7.5 13.1 7.7 6.8 2.7 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Csm1_N PF18504.1 CDJ89536.1 - 5 7.5 12.4 9.9 6.6 1.9 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain FapA PF03961.13 CDJ89536.1 - 5.9 5.4 9.5 12 4.3 9.5 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A APG6_N PF17675.1 CDJ89536.1 - 8.5 6.9 14.9 11 6.5 2.5 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region TauE PF01925.19 CDJ89539.1 - 1.4e-16 60.8 20.3 1.4e-16 60.8 20.3 2.1 1 1 1 2 2 2 1 Sulfite exporter TauE/SafE RseC_MucC PF04246.12 CDJ89539.1 - 4.9 7.1 6.7 0.98 9.4 0.3 2.9 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC CAP PF00188.26 CDJ89540.1 - 8.8e-22 78.3 1.5 5e-13 50.0 0.1 2.5 2 0 0 2 2 2 2 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ89540.1 - 0.00052 20.3 0.5 1 9.6 0.2 2.8 2 1 0 2 2 2 2 Ancylostoma-associated secreted protein related DX PF01666.17 CDJ89540.1 - 0.42 11.1 5.0 0.62 10.6 3.3 2.3 3 0 0 3 3 3 0 DX module TRAM_LAG1_CLN8 PF03798.16 CDJ89541.1 - 3.1e-18 66.2 24.1 3.1e-18 66.2 24.1 2.0 2 0 0 2 2 2 1 TLC domain Acyl_transf_3 PF01757.22 CDJ89542.1 - 5.7e-23 81.5 40.7 5.7e-23 81.5 40.7 2.0 2 0 0 2 2 2 2 Acyltransferase family Sec20 PF03908.13 CDJ89543.1 - 0.00055 19.8 0.1 0.00066 19.5 0.1 1.2 1 0 0 1 1 1 1 Sec20 Use1 PF09753.9 CDJ89543.1 - 0.018 14.8 0.0 0.022 14.5 0.0 1.0 1 0 0 1 1 1 0 Membrane fusion protein Use1 APG17 PF04108.12 CDJ89543.1 - 0.024 13.8 0.0 0.029 13.5 0.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg17 SNARE PF05739.19 CDJ89543.1 - 0.12 12.4 0.3 0.28 11.2 0.3 1.7 1 1 0 1 1 1 0 SNARE domain Peptidase_C78 PF07910.13 CDJ89544.1 - 1.6e-47 161.7 0.0 2.3e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 CDJ89544.1 - 0.0076 15.7 1.3 0.37 10.2 0.4 2.9 1 1 2 3 3 3 1 Peptidase family C54 TraB PF01963.17 CDJ89545.1 - 1.2e-28 100.7 0.1 1.8e-28 100.2 0.1 1.1 1 0 0 1 1 1 1 TraB family JAMP PF05571.12 CDJ89546.1 - 1.8e-42 146.0 19.0 3.5e-42 145.0 19.0 1.5 1 0 0 1 1 1 1 JNK1/MAPK8-associated membrane protein Per1 PF04080.13 CDJ89546.1 - 5.1e-16 59.2 12.0 5.1e-16 59.2 12.0 3.0 2 1 0 2 2 2 1 Per1-like family DUF2207 PF09972.9 CDJ89546.1 - 4.7 5.9 9.1 0.1 11.4 2.1 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) PARP PF00644.20 CDJ89547.1 - 6.6e-59 198.8 0.0 1.2e-58 197.9 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 CDJ89547.1 - 1.3e-42 145.1 1.9 2.9e-42 144.0 1.9 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain zf-PARP PF00645.18 CDJ89547.1 - 4e-29 101.3 6.5 5.6e-17 62.4 0.5 3.6 3 0 0 3 3 3 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region WGR PF05406.15 CDJ89547.1 - 2.8e-22 78.6 0.3 7.6e-22 77.2 0.3 1.8 1 0 0 1 1 1 1 WGR domain PADR1 PF08063.12 CDJ89547.1 - 4.9e-15 55.1 4.9 1.4e-14 53.6 4.9 1.8 1 0 0 1 1 1 1 PADR1 (NUC008) domain DUF1758 PF05585.12 CDJ89548.1 - 8.5e-13 48.4 0.0 7.9e-06 25.7 0.0 2.5 2 1 0 2 2 2 2 Putative peptidase (DUF1758) gag-asp_proteas PF13975.6 CDJ89548.1 - 2e-11 44.3 0.0 0.00031 21.2 0.0 2.5 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ89548.1 - 5e-11 43.1 0.0 0.00054 20.6 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.11 CDJ89548.1 - 0.00036 20.3 0.0 0.39 10.5 0.0 2.3 2 0 0 2 2 2 2 Retroviral aspartyl protease RVP PF00077.20 CDJ89548.1 - 0.00047 20.4 0.0 0.84 10.0 0.0 2.7 2 0 0 2 2 2 2 Retroviral aspartyl protease Peptidase_A2B PF12384.8 CDJ89548.1 - 0.0046 16.5 0.0 3.3 7.2 0.0 2.2 2 0 0 2 2 2 2 Ty3 transposon peptidase POM121 PF15229.6 CDJ89548.1 - 0.15 11.7 11.4 1.9 8.1 1.0 3.2 4 0 0 4 4 4 0 POM121 family G6PD_C PF02781.16 CDJ89548.1 - 0.16 11.1 0.3 11 5.1 0.0 2.2 2 0 0 2 2 2 0 Glucose-6-phosphate dehydrogenase, C-terminal domain Coatamer_beta_C PF07718.12 CDJ89548.1 - 0.39 10.6 1.5 66 3.4 0.0 3.8 4 0 0 4 4 4 0 Coatomer beta C-terminal region Ion_trans_2 PF07885.16 CDJ89549.1 - 7.8e-26 89.8 19.1 6.8e-14 51.6 10.6 2.4 2 0 0 2 2 2 2 Ion channel fn3 PF00041.21 CDJ89549.1 - 7.1e-21 74.4 1.1 3.6e-10 40.0 0.0 2.4 2 0 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CDJ89549.1 - 0.00013 22.5 4.4 0.0041 17.7 0.0 3.5 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain Lig_chan PF00060.26 CDJ89549.1 - 0.038 13.8 1.3 0.097 12.5 0.0 2.1 2 0 0 2 2 2 0 Ligand-gated ion channel PTH2 PF01981.16 CDJ89550.1 - 3.3e-32 111.2 0.0 5.9e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 COX16 PF14138.6 CDJ89550.1 - 4.5e-19 68.7 0.0 8.6e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 UBA PF00627.31 CDJ89550.1 - 4.5e-08 32.8 0.1 1.1e-07 31.7 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain LBP_BPI_CETP_C PF02886.17 CDJ89551.1 - 1.1e-22 80.7 0.0 1.6e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 CDJ89551.1 - 5.3e-05 22.9 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain 7tm_1 PF00001.21 CDJ89552.1 - 7.8e-46 156.5 13.3 1e-45 156.1 13.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ89552.1 - 6.7e-07 28.9 9.1 9.7e-07 28.4 8.4 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 CDJ89552.1 - 1.9e-05 24.5 2.2 1.9e-05 24.5 2.2 1.5 1 1 0 1 1 1 1 Olfactory receptor Selenoprotein_S PF06936.11 CDJ89552.1 - 0.11 12.3 0.2 2.4 7.9 0.0 2.1 2 0 0 2 2 2 0 Selenoprotein S (SelS) 7TM_GPCR_Srt PF10321.9 CDJ89553.1 - 2.3e-25 89.2 13.2 4.4e-17 62.0 0.8 2.3 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srt SelP_N PF04592.14 CDJ89554.1 - 1.2e-06 28.1 0.6 1.2e-06 28.1 0.6 3.0 1 1 1 2 2 2 1 Selenoprotein P, N terminal region TFIIA PF03153.13 CDJ89554.1 - 0.0009 19.4 25.6 0.0012 18.9 25.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit AhpC-TSA PF00578.21 CDJ89554.1 - 0.012 15.6 0.8 0.04 13.8 0.0 2.1 2 0 0 2 2 2 0 AhpC/TSA family Redoxin PF08534.10 CDJ89554.1 - 0.07 12.8 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 Redoxin Sarcoglycan_2 PF05510.13 CDJ89554.1 - 0.1 11.3 3.3 0.16 10.7 3.3 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon AF-4 PF05110.13 CDJ89554.1 - 0.11 10.6 14.8 0.13 10.3 14.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Suf PF05843.14 CDJ89554.1 - 0.7 9.8 11.4 1 9.3 11.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 CDJ89554.1 - 1.1 9.2 3.8 1.7 8.6 3.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF853 PF05872.12 CDJ89554.1 - 3.5 6.1 5.7 4.8 5.7 5.7 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Hydin_ADK PF17213.3 CDJ89554.1 - 4.1 7.6 7.3 7.1 6.9 7.3 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain PP2C_2 PF13672.6 CDJ89555.1 - 5.4e-12 45.8 0.1 1.3e-11 44.6 0.1 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CDJ89555.1 - 1.7e-05 24.8 0.0 5e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Ig_3 PF13927.6 CDJ89558.1 - 1.2e-16 61.0 0.8 2.6e-15 56.8 0.0 2.6 3 0 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 CDJ89558.1 - 2.2e-13 50.3 0.0 1.5e-12 47.6 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 CDJ89558.1 - 3.1e-13 49.6 0.0 7.7e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 CDJ89558.1 - 1.2e-10 41.4 0.0 3e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain TSP_1 PF00090.19 CDJ89558.1 - 3.1e-08 33.7 24.9 1.9e-07 31.2 6.9 3.5 3 0 0 3 3 3 2 Thrombospondin type 1 domain V-set PF07686.17 CDJ89558.1 - 6.9e-07 29.4 0.1 0.0084 16.3 0.0 2.6 1 1 1 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDJ89558.1 - 3.3e-05 23.9 0.0 7.3e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 CDJ89558.1 - 0.019 15.4 0.0 0.09 13.2 0.0 2.1 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 CDJ89558.1 - 0.02 14.4 0.0 0.048 13.2 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Receptor_2B4 PF11465.8 CDJ89558.1 - 0.024 14.8 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 Ig_4 PF16680.5 CDJ89558.1 - 0.068 13.4 0.0 0.23 11.8 0.0 2.0 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain SNF PF00209.18 CDJ89559.1 - 3.2e-54 184.5 29.2 3.6e-54 184.3 29.2 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Laps PF10169.9 CDJ89560.1 - 0.00046 20.8 10.4 0.0021 18.6 10.4 1.8 1 1 0 1 1 1 1 Learning-associated protein Ribosomal_L37 PF08561.10 CDJ89560.1 - 5.3 7.6 12.3 1.6 9.3 1.5 2.1 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L37 Xpo1 PF08389.12 CDJ89561.1 - 2.3e-26 92.6 0.1 4.2e-26 91.8 0.1 1.4 1 0 0 1 1 1 1 Exportin 1-like protein Kunitz_BPTI PF00014.23 CDJ89562.1 - 2.6e-16 59.6 3.0 4.4e-16 58.9 3.0 1.4 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain LSM PF01423.22 CDJ89564.1 - 8.8e-08 31.7 0.0 2.3e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 LSM domain Exonuc_VII_L PF02601.15 CDJ89564.1 - 0.16 11.5 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_C24 PF03510.14 CDJ89565.1 - 0.25 11.9 0.9 0.7 10.4 0.9 1.7 1 0 0 1 1 1 0 2C endopeptidase (C24) cysteine protease family Arg_decarbox_C PF17944.1 CDJ89565.1 - 5.1 7.7 7.3 28 5.3 0.7 3.4 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension Nop14 PF04147.12 CDJ89567.1 - 2.1e-188 628.5 33.5 2.5e-188 628.2 33.5 1.0 1 0 0 1 1 1 1 Nop14-like family SMAP PF15477.6 CDJ89567.1 - 0.045 14.7 1.2 1.9 9.5 0.0 3.2 2 0 0 2 2 2 0 Small acidic protein family SIKE PF05769.11 CDJ89568.1 - 3.9e-17 62.8 9.5 5.4e-17 62.3 9.5 1.2 1 0 0 1 1 1 1 SIKE family NEMO PF11577.8 CDJ89568.1 - 0.035 14.1 4.8 2.1 8.5 0.3 3.0 2 1 0 2 2 2 0 NF-kappa-B essential modulator NEMO CheZ PF04344.13 CDJ89568.1 - 0.038 13.9 3.0 3.5 7.5 0.2 2.4 1 1 1 2 2 2 0 Chemotaxis phosphatase, CheZ Cauli_AT PF03233.13 CDJ89568.1 - 0.039 13.9 1.2 0.13 12.2 0.7 2.0 1 1 1 2 2 2 0 Aphid transmission protein DUF5094 PF17015.5 CDJ89568.1 - 0.095 12.8 6.7 1 9.4 1.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5094) USP8_interact PF08941.10 CDJ89568.1 - 0.12 12.1 0.2 0.12 12.1 0.2 2.8 2 1 0 2 2 2 0 USP8 interacting PABP PF00658.18 CDJ89568.1 - 1.3 9.2 4.0 2.9 8.1 0.5 2.6 2 0 0 2 2 2 0 Poly-adenylate binding protein, unique domain Med7 PF05983.11 CDJ89569.1 - 1.7e-44 152.2 7.2 5.2e-43 147.4 7.2 2.4 1 1 0 1 1 1 1 MED7 protein UQ_con PF00179.26 CDJ89569.1 - 6.2e-17 61.6 0.2 3.1e-16 59.3 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Seryl_tRNA_N PF02403.22 CDJ89569.1 - 0.13 12.5 0.8 4.5 7.5 0.0 2.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain CTD_bind PF04818.13 CDJ89570.1 - 8.6e-10 39.3 0.3 2.9e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Bax1-I PF01027.20 CDJ89572.1 - 1.7e-33 116.2 11.9 2e-33 116.0 11.9 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF3487 PF11990.8 CDJ89572.1 - 0.041 13.8 1.6 0.094 12.6 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3487) AzlD PF05437.12 CDJ89572.1 - 0.2 11.9 10.8 0.05 13.8 2.0 2.8 3 0 0 3 3 3 0 Branched-chain amino acid transport protein (AzlD) CHORD PF04968.12 CDJ89573.1 - 2.5e-48 162.6 24.5 2.4e-24 85.8 8.6 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 CDJ89573.1 - 0.00058 20.8 0.0 0.0015 19.5 0.0 1.7 1 0 0 1 1 1 1 CS domain RRN3 PF05327.11 CDJ89575.1 - 0.41 9.1 1.9 0.47 8.9 1.9 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 YqfQ PF14181.6 CDJ89575.1 - 2 8.6 5.9 2.3 8.4 5.9 1.1 1 0 0 1 1 1 0 YqfQ-like protein EVE PF01878.18 CDJ89576.1 - 0.098 12.7 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 EVE domain Pns11_12 PF17464.2 CDJ89576.1 - 0.82 9.3 8.3 1.3 8.7 8.3 1.2 1 0 0 1 1 1 0 Non-structural protein 11 and 12 NPR3 PF03666.13 CDJ89576.1 - 1.7 7.4 4.6 2.1 7.0 4.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Peroxin-22 PF12827.7 CDJ89577.1 - 0.0083 16.0 1.2 1.1 9.2 0.1 3.0 3 1 1 4 4 4 2 Peroxisomal biogenesis protein family Ku PF02735.16 CDJ89578.1 - 1.3e-45 155.7 0.0 2.6e-45 154.6 0.0 1.5 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 CDJ89578.1 - 2.8e-08 33.8 0.0 4.4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 CDJ89578.1 - 9.7e-08 32.6 0.1 3.1e-07 31.0 0.1 1.9 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm HeH PF12949.7 CDJ89578.1 - 0.00075 19.2 0.2 0.0066 16.1 0.2 2.3 1 1 0 1 1 1 1 HeH/LEM domain DNA_pol_B PF00136.21 CDJ89579.1 - 8.2e-111 370.9 3.3 2.1e-110 369.6 3.3 1.6 1 1 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 CDJ89579.1 - 7.7e-30 104.0 2.2 8.8e-30 103.8 0.6 2.0 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 CDJ89579.1 - 6.5e-24 84.7 0.0 1.2e-23 83.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 CDJ89579.1 - 8.6e-20 70.6 6.3 3.8e-19 68.5 6.3 2.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 CDJ89579.1 - 0.00076 18.5 0.1 0.0023 16.9 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral EntA_Immun PF08951.10 CDJ89579.1 - 0.0072 16.7 0.2 10 6.5 0.0 3.3 2 0 0 2 2 2 2 Enterocin A Immunity DUF1744 PF08490.12 CDJ89579.1 - 0.0081 14.8 0.2 0.015 13.8 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) CLN3 PF02487.17 CDJ89580.1 - 1.1e-139 466.0 5.0 1.2e-139 465.8 5.0 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 CDJ89580.1 - 0.00014 21.0 14.3 0.0028 16.7 13.7 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Motile_Sperm PF00635.26 CDJ89581.1 - 1.3e-21 76.5 0.0 1.6e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ABC_tran PF00005.27 CDJ89582.1 - 1e-19 71.4 0.0 1.8e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CDJ89582.1 - 3.3e-12 46.8 0.3 4.9e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CDJ89582.1 - 0.018 15.6 0.3 0.032 14.7 0.3 1.4 1 0 0 1 1 1 0 AAA domain Patched PF02460.18 CDJ89583.1 - 2.9e-62 210.9 12.6 5.8e-52 176.8 14.8 2.5 1 1 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 CDJ89583.1 - 5.4e-29 101.0 4.0 5.4e-29 101.0 4.0 1.8 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation SH3_1 PF00018.28 CDJ89584.1 - 3.2e-08 33.1 0.0 4.3e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CDJ89584.1 - 5.8e-07 29.3 0.0 6.9e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 CDJ89584.1 - 0.00044 20.5 0.0 0.00058 20.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_2 PF07653.17 CDJ89584.1 - 0.00096 18.8 0.0 0.0011 18.6 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain DUF3629 PF12302.8 CDJ89585.1 - 0.016 14.7 6.2 0.032 13.7 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3629) DUF3489 PF11994.8 CDJ89586.1 - 0.058 13.5 0.1 0.18 11.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3489) Meis_PKNOX_N PF16493.5 CDJ89588.1 - 2e-38 130.6 1.0 3.5e-38 129.8 1.0 1.4 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 VWA PF00092.28 CDJ89590.1 - 4.2e-56 190.0 0.1 3.8e-30 105.4 0.1 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 CDJ89590.1 - 5.1e-26 91.4 0.4 4.5e-12 46.6 0.0 2.6 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_CoxE PF05762.14 CDJ89590.1 - 1.9e-09 37.3 0.2 0.00041 19.8 0.0 2.4 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein DUF1194 PF06707.11 CDJ89590.1 - 2e-07 30.5 0.9 0.004 16.4 0.9 3.0 2 2 0 2 2 2 2 Protein of unknown function (DUF1194) VWA_3 PF13768.6 CDJ89590.1 - 4.7e-05 23.4 0.1 0.053 13.5 0.0 3.3 2 1 2 4 4 4 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 CDJ89590.1 - 0.00012 22.2 0.2 0.02 15.0 0.0 3.0 2 1 0 2 2 2 1 vWA found in TerF C terminus Tir_receptor_C PF07489.11 CDJ89590.1 - 0.037 14.0 4.1 0.061 13.3 4.1 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus DUF501 PF04417.12 CDJ89590.1 - 0.091 12.6 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF501) Dicty_REP PF05086.12 CDJ89590.1 - 0.39 8.6 6.3 0.53 8.2 6.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 CDJ89590.1 - 0.78 9.7 18.6 1.5 8.8 18.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein rve PF00665.26 CDJ89591.1 - 1.1e-24 86.9 0.0 1.8e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ89591.1 - 5.7e-07 29.5 0.2 1.1e-06 28.6 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CDJ89591.1 - 4.9e-05 23.0 0.3 0.00077 19.2 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 CDJ89591.1 - 0.039 14.2 0.1 0.063 13.5 0.1 1.4 1 0 0 1 1 1 0 H2C2 zinc finger Exo_endo_phos_2 PF14529.6 CDJ89591.1 - 0.048 13.5 0.0 0.9 9.4 0.0 2.9 2 2 1 3 3 3 0 Endonuclease-reverse transcriptase DUF818 PF05677.12 CDJ89592.1 - 0.2 10.6 0.7 0.27 10.2 0.7 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) TNFR_16_TM PF18422.1 CDJ89592.1 - 4.9 7.2 7.1 30 4.7 7.1 2.1 1 1 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain BCSC_C PF05420.11 CDJ89593.1 - 0.073 12.2 0.1 0.081 12.1 0.1 1.0 1 0 0 1 1 1 0 Cellulose synthase operon protein C C-terminus (BCSC_C) zf-C2H2_4 PF13894.6 CDJ89594.1 - 0.023 15.5 19.5 1.5 9.9 3.3 5.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDJ89594.1 - 0.028 14.9 6.9 2.6 8.6 0.4 3.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.26 CDJ89594.1 - 0.44 11.1 22.3 0.27 11.8 3.3 4.7 5 0 0 5 5 5 0 Zinc finger, C2H2 type Actin_micro PF17003.5 CDJ89594.1 - 5.9 6.0 8.1 0.33 10.1 1.6 2.1 2 0 0 2 2 2 0 Putative actin-like family adh_short_C2 PF13561.6 CDJ89595.1 - 1.5e-64 217.8 0.4 1.7e-64 217.6 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDJ89595.1 - 4.7e-48 163.2 1.4 6.1e-48 162.9 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDJ89595.1 - 1.6e-18 67.2 0.3 2.5e-18 66.6 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDJ89595.1 - 1.5e-06 27.8 0.1 2.1e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CDJ89595.1 - 4.7e-05 22.5 0.5 6.3e-05 22.1 0.5 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 CDJ89595.1 - 7.1e-05 23.1 0.1 0.00016 22.0 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 CDJ89595.1 - 0.0046 16.1 0.1 0.0066 15.6 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3HCDH_N PF02737.18 CDJ89595.1 - 0.018 14.9 0.1 0.041 13.8 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 CDJ89595.1 - 0.059 13.6 0.7 0.36 11.1 0.0 2.3 2 1 1 3 3 3 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 CDJ89595.1 - 0.16 11.3 0.6 1.8 7.9 0.0 2.6 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Antimicrobial_2 PF08023.12 CDJ89595.1 - 1 9.9 3.7 7.3 7.2 0.4 3.4 3 0 0 3 3 3 0 Frog antimicrobial peptide RVT_1 PF00078.27 CDJ89596.1 - 2.8e-26 92.4 0.0 4e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_M14 PF00246.24 CDJ89597.1 - 3.3e-74 250.3 0.1 4.4e-74 249.9 0.1 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase CarbopepD_reg_2 PF13715.6 CDJ89597.1 - 1.2e-06 28.4 0.0 2.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 CarboxypepD_reg-like domain AstE_AspA PF04952.14 CDJ89597.1 - 0.0074 15.4 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family MetallophosN PF16371.5 CDJ89597.1 - 0.029 14.6 0.1 2.9 8.2 0.1 2.4 2 0 0 2 2 2 0 N terminal of Calcineurin-like phosphoesterase Sugar_tr PF00083.24 CDJ89598.1 - 1.3e-53 182.4 19.4 1.5e-53 182.3 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ89598.1 - 9.4e-20 70.8 25.5 9.4e-20 70.8 25.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Keratin_2_head PF16208.5 CDJ89600.1 - 0.011 15.8 13.1 0.013 15.7 13.1 1.0 1 0 0 1 1 1 0 Keratin type II head Pkinase_Tyr PF07714.17 CDJ89601.1 - 8e-76 254.7 0.0 1.1e-75 254.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ89601.1 - 1.3e-45 155.8 0.0 1.9e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDJ89601.1 - 5.3e-08 32.9 0.0 1.2e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Kinase-like PF14531.6 CDJ89601.1 - 0.058 12.7 0.0 0.094 12.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 CDJ89601.1 - 0.061 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TFIID-31kDa PF02291.15 CDJ89603.1 - 2.9e-29 101.6 0.0 3.9e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 CDJ89603.1 - 0.16 12.3 0.1 0.27 11.7 0.1 1.2 1 0 0 1 1 1 0 CENP-S protein EF-hand_1 PF00036.32 CDJ89604.1 - 1.7e-10 39.7 0.6 0.00024 20.4 0.0 3.8 4 1 1 5 5 5 2 EF hand EF-hand_6 PF13405.6 CDJ89604.1 - 4.7e-10 38.6 0.2 0.0014 18.4 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CDJ89604.1 - 4.9e-10 39.7 0.2 0.0015 18.9 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ89604.1 - 3.4e-06 26.8 0.9 0.088 12.7 0.0 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 CDJ89604.1 - 0.00045 20.5 0.0 0.32 11.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.13 CDJ89604.1 - 0.024 14.6 0.0 3.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF3349 PF11829.8 CDJ89604.1 - 0.11 13.3 0.0 12 6.8 0.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3349) EF-hand_14 PF17959.1 CDJ89604.1 - 0.15 12.4 0.0 13 6.2 0.0 2.5 1 1 1 2 2 2 0 EF-hand domain DUF2267 PF10025.9 CDJ89604.1 - 0.2 12.0 0.8 1.3 9.4 0.3 2.2 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) GPHH PF16905.5 CDJ89604.1 - 0.22 11.3 0.0 3.4 7.5 0.0 2.2 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated Hus1 PF04005.12 CDJ89605.1 - 1.2e-28 100.1 0.2 1.8e-28 99.5 0.2 1.3 1 0 0 1 1 1 1 Hus1-like protein COG7 PF10191.9 CDJ89605.1 - 0.046 12.0 0.1 0.062 11.5 0.1 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) Lig_chan PF00060.26 CDJ89606.1 - 4.4e-24 85.0 0.0 6.9e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 CDJ89606.1 - 1.7e-19 70.2 0.0 3.8e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 CDJ89606.1 - 7.1e-10 39.1 0.0 2.3e-09 37.5 0.0 1.8 1 1 1 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site Ion_trans_2 PF07885.16 CDJ89606.1 - 0.022 14.7 0.1 0.065 13.2 0.1 1.7 1 0 0 1 1 1 0 Ion channel RVT_1 PF00078.27 CDJ89608.1 - 2e-13 50.4 0.0 2.4e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Gly-zipper_Omp PF13488.6 CDJ89609.1 - 0.00083 19.3 6.2 0.0016 18.4 6.2 1.4 1 0 0 1 1 1 1 Glycine zipper Bacteriocin_IIc PF10439.9 CDJ89609.1 - 0.036 14.2 12.3 0.064 13.4 12.3 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide ThrE PF06738.12 CDJ89609.1 - 0.055 12.8 0.4 0.09 12.1 0.2 1.5 1 1 1 2 2 2 0 Putative threonine/serine exporter Gly-zipper_YMGG PF13441.6 CDJ89609.1 - 0.061 13.1 11.4 0.1 12.4 11.4 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper MccV PF17508.2 CDJ89609.1 - 0.072 13.7 0.2 0.1 13.2 0.2 1.3 1 0 0 1 1 1 0 Microcin V bacteriocin DUF3482 PF11981.8 CDJ89609.1 - 1.3 8.4 7.1 1.9 7.8 6.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3482) Rick_17kDa_Anti PF05433.15 CDJ89609.1 - 3.5 7.6 15.0 14 5.7 14.7 1.9 1 1 1 2 2 2 0 Glycine zipper 2TM domain GSH_synth_ATP PF03917.17 CDJ89610.1 - 9.1e-101 337.3 0.0 3.5e-72 243.3 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 CDJ89610.1 - 6.3e-29 100.5 0.0 2.2e-28 98.7 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic glutathione synthase MAGE PF01454.19 CDJ89610.1 - 0.025 14.3 0.1 0.077 12.7 0.0 2.0 2 1 0 2 2 2 0 MAGE family AbiEi_3_N PF17194.4 CDJ89610.1 - 0.1 12.7 0.0 6.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain BORCS7 PF16088.5 CDJ89612.1 - 8e-09 35.7 0.2 9.8e-09 35.4 0.2 1.1 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 7 DUF818 PF05677.12 CDJ89613.1 - 0.2 10.6 0.7 0.27 10.2 0.7 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) TNFR_16_TM PF18422.1 CDJ89613.1 - 4.9 7.2 7.1 30 4.7 7.1 2.1 1 1 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain BCSC_C PF05420.11 CDJ89614.1 - 0.073 12.2 0.1 0.081 12.1 0.1 1.0 1 0 0 1 1 1 0 Cellulose synthase operon protein C C-terminus (BCSC_C) zf-C2H2_4 PF13894.6 CDJ89615.1 - 0.12 13.3 28.8 1.5 9.9 3.3 6.0 5 0 0 5 5 5 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDJ89615.1 - 0.8 10.3 12.8 2.7 8.6 0.4 4.4 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2 PF00096.26 CDJ89615.1 - 5.2 7.7 31.6 0.28 11.7 3.3 5.7 6 0 0 6 6 6 0 Zinc finger, C2H2 type Actin_micro PF17003.5 CDJ89615.1 - 5.7 6.0 8.2 0.34 10.1 1.6 2.2 2 0 0 2 2 2 0 Putative actin-like family c-SKI_SMAD_bind PF08782.10 CDJ89615.1 - 8.1 6.8 9.7 1.2 9.4 1.5 2.6 2 0 0 2 2 2 0 c-SKI Smad4 binding domain adh_short_C2 PF13561.6 CDJ89616.1 - 1.5e-64 217.8 0.4 1.7e-64 217.6 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDJ89616.1 - 4.7e-48 163.2 1.4 6.1e-48 162.9 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDJ89616.1 - 1.6e-18 67.2 0.3 2.5e-18 66.6 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDJ89616.1 - 1.5e-06 27.8 0.1 2.1e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CDJ89616.1 - 4.7e-05 22.5 0.5 6.3e-05 22.1 0.5 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 CDJ89616.1 - 7.1e-05 23.1 0.1 0.00016 22.0 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 CDJ89616.1 - 0.0046 16.1 0.1 0.0066 15.6 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3HCDH_N PF02737.18 CDJ89616.1 - 0.018 14.9 0.1 0.041 13.8 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 CDJ89616.1 - 0.059 13.6 0.7 0.36 11.1 0.0 2.3 2 1 1 3 3 3 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 CDJ89616.1 - 0.16 11.3 0.6 1.8 7.9 0.0 2.6 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Antimicrobial_2 PF08023.12 CDJ89616.1 - 1 9.9 3.7 7.3 7.2 0.4 3.4 3 0 0 3 3 3 0 Frog antimicrobial peptide RVT_1 PF00078.27 CDJ89617.1 - 2.8e-26 92.4 0.0 4e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_M14 PF00246.24 CDJ89618.1 - 3.3e-74 250.3 0.1 4.4e-74 249.9 0.1 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase CarbopepD_reg_2 PF13715.6 CDJ89618.1 - 1.2e-06 28.4 0.0 2.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 CarboxypepD_reg-like domain AstE_AspA PF04952.14 CDJ89618.1 - 0.0074 15.4 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family MetallophosN PF16371.5 CDJ89618.1 - 0.029 14.6 0.1 2.9 8.2 0.1 2.4 2 0 0 2 2 2 0 N terminal of Calcineurin-like phosphoesterase Sugar_tr PF00083.24 CDJ89619.1 - 1.3e-53 182.4 19.4 1.5e-53 182.3 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ89619.1 - 9.4e-20 70.8 25.5 9.4e-20 70.8 25.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 CDJ89621.1 - 2.3e-05 23.9 0.0 2.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Col_cuticle_N PF01484.17 CDJ89622.1 - 1.9e-12 47.0 3.2 2.4e-12 46.7 3.2 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ89622.1 - 0.00012 21.8 49.1 0.00012 21.8 49.1 5.2 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) DUF3887 PF13026.6 CDJ89622.1 - 0.11 13.3 0.0 0.16 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) SIR2 PF02146.17 CDJ89623.1 - 2.2e-60 203.6 0.0 3.5e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 CDJ89623.1 - 0.0014 18.4 0.0 0.28 10.9 0.0 2.6 2 1 1 3 3 3 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 CDJ89623.1 - 0.0067 16.2 0.1 0.02 14.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF592) zf-4CXXC_R1 PF10497.9 CDJ89623.1 - 0.052 13.8 0.1 0.14 12.4 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 7TM_GPCR_Str PF10326.9 CDJ89624.1 - 2.6e-14 53.3 3.1 3.3e-14 53.0 3.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srj PF10319.9 CDJ89624.1 - 4.2e-09 36.2 3.0 4.8e-09 36.0 3.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Srd PF10317.9 CDJ89624.1 - 1.9e-07 30.6 2.1 2.3e-07 30.3 2.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Srh PF10318.9 CDJ89624.1 - 1.7e-06 27.3 0.8 1.8e-06 27.2 0.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Sri PF10327.9 CDJ89624.1 - 0.0005 19.4 0.4 0.00062 19.0 0.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri Neur_chan_LBD PF02931.23 CDJ89625.1 - 3.4e-21 75.7 0.4 1.2e-10 41.2 0.1 3.0 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ89625.1 - 2.8e-13 50.5 3.3 1.6e-11 44.7 1.6 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region TLD PF07534.16 CDJ89625.1 - 0.13 12.4 0.0 0.31 11.3 0.0 1.6 1 1 0 1 1 1 0 TLD Neur_chan_LBD PF02931.23 CDJ89626.1 - 1.9e-31 109.2 4.0 3.6e-31 108.3 4.0 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ89626.1 - 1.1e-06 28.9 8.4 0.00016 21.8 5.4 2.4 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Arf PF00025.21 CDJ89627.1 - 7.9e-79 263.1 0.1 9.6e-79 262.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CDJ89627.1 - 4.2e-14 52.8 0.0 5.9e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CDJ89627.1 - 5.5e-14 52.0 0.0 6.7e-14 51.7 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CDJ89627.1 - 1.8e-12 47.2 0.0 1.9e-12 47.1 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CDJ89627.1 - 2e-11 43.7 1.1 1.4e-07 31.0 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CDJ89627.1 - 1.8e-10 40.6 0.0 2.2e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDJ89627.1 - 2.4e-05 24.4 0.0 3.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CDJ89627.1 - 0.0038 16.5 0.3 0.024 14.0 0.1 1.9 2 0 0 2 2 2 1 6-phosphofructo-2-kinase DDRGK PF09756.9 CDJ89628.1 - 1e-58 198.1 30.0 1.6e-58 197.4 30.0 1.3 1 0 0 1 1 1 1 DDRGK domain FeoC PF09012.10 CDJ89628.1 - 0.0011 19.0 0.4 0.57 10.3 0.0 2.9 3 0 0 3 3 3 2 FeoC like transcriptional regulator DUF3347 PF11827.8 CDJ89628.1 - 0.27 11.4 6.4 0.41 10.8 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) DDE_Tnp_ISL3 PF01610.17 CDJ89628.1 - 0.37 10.5 10.2 0.66 9.7 10.2 1.4 1 0 0 1 1 1 0 Transposase DAPDH_C PF16654.5 CDJ89628.1 - 1.4 8.8 4.0 0.86 9.4 1.9 1.7 1 1 1 2 2 2 0 Diaminopimelic acid dehydrogenase C-terminal domain Atg14 PF10186.9 CDJ89628.1 - 2.5 7.1 8.4 3.5 6.6 8.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PA26 PF04636.13 CDJ89628.1 - 2.6 6.9 8.7 3.4 6.5 8.7 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) AAA_11 PF13086.6 CDJ89628.1 - 3.3 7.4 10.9 4.8 6.9 10.9 1.4 1 0 0 1 1 1 0 AAA domain Mt_ATP-synt_D PF05873.12 CDJ89629.1 - 3e-36 124.6 1.1 3.9e-36 124.2 1.1 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) adh_short PF00106.25 CDJ89630.1 - 5.3e-27 94.5 0.0 3e-26 92.1 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ89630.1 - 3.3e-14 53.0 0.1 8.3e-14 51.7 0.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ89630.1 - 2.2e-11 44.0 0.0 3.6e-11 43.3 0.0 1.4 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 CDJ89630.1 - 0.00038 20.7 0.3 0.0035 17.6 0.1 2.4 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 CDJ89630.1 - 0.013 15.0 0.1 0.065 12.7 0.1 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CDJ89630.1 - 0.021 14.0 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF825 PF05695.12 CDJ89630.1 - 0.061 10.5 0.1 0.079 10.1 0.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) adh_short PF00106.25 CDJ89631.1 - 3.4e-06 26.6 0.0 6.6e-05 22.4 0.0 2.4 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ89631.1 - 0.0065 16.0 0.0 0.054 13.1 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1075 PF06388.11 CDJ89632.1 - 3.4 7.8 6.8 2.3 8.3 1.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1075) Spt5_N PF11942.8 CDJ89632.1 - 6.9 7.7 8.8 32 5.6 8.8 1.9 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DZF PF07528.14 CDJ89633.1 - 4.1e-76 255.9 0.3 8.7e-76 254.8 0.0 1.6 2 0 0 2 2 2 1 DZF domain ARD PF03079.14 CDJ89634.1 - 6.9e-53 179.0 0.1 7.7e-53 178.9 0.1 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 CDJ89634.1 - 0.0069 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain EutQ PF06249.12 CDJ89634.1 - 0.095 12.5 0.0 0.13 12.0 0.0 1.3 1 1 0 1 1 1 0 Ethanolamine utilisation protein EutQ Myosin_head PF00063.21 CDJ89635.1 - 6.9e-238 791.3 0.0 8.2e-238 791.0 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 CDJ89635.1 - 7.2e-18 62.6 43.5 1.2e-06 27.8 0.1 6.8 6 0 0 6 6 6 6 IQ calmodulin-binding motif AAA_22 PF13401.6 CDJ89635.1 - 0.0026 18.0 0.0 0.0077 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ89635.1 - 0.0096 16.3 0.0 0.25 11.7 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain Myosin_N PF02736.19 CDJ89635.1 - 0.016 15.0 0.3 0.076 12.9 0.5 2.1 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain IQCJ-SCHIP1 PF15157.6 CDJ89635.1 - 0.15 11.9 0.4 2 8.3 0.2 2.4 2 0 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif UCH PF00443.29 CDJ89636.1 - 9.1e-53 179.4 0.0 1.1e-52 179.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ89636.1 - 5.1e-26 92.0 1.0 1.8e-25 90.2 1.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 CDJ89636.1 - 3.1e-05 23.6 10.0 0.022 14.3 0.1 3.3 4 0 0 4 4 4 3 Ubiquitin-specific peptidase-like, SUMO isopeptidase GRP PF07172.11 CDJ89637.1 - 0.019 15.6 3.6 0.029 15.0 3.6 1.3 1 0 0 1 1 1 0 Glycine rich protein family DUF4799 PF16056.5 CDJ89637.1 - 1.1 8.4 8.5 0.055 12.6 2.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4799) Folliculin_C PF16692.5 CDJ89638.1 - 2.3e-34 119.1 0.0 3.4e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Folliculin C-terminal domain COX8 PF02285.15 CDJ89639.1 - 0.024 14.5 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII DUF818 PF05677.12 CDJ89641.1 - 0.2 10.6 0.7 0.27 10.2 0.7 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) TNFR_16_TM PF18422.1 CDJ89641.1 - 4.9 7.2 7.1 30 4.7 7.1 2.1 1 1 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain BCSC_C PF05420.11 CDJ89642.1 - 0.073 12.2 0.1 0.081 12.1 0.1 1.0 1 0 0 1 1 1 0 Cellulose synthase operon protein C C-terminus (BCSC_C) zf-C2H2_4 PF13894.6 CDJ89643.1 - 0.023 15.5 19.5 1.5 9.9 3.3 5.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDJ89643.1 - 0.028 14.9 6.9 2.6 8.6 0.4 3.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.26 CDJ89643.1 - 0.44 11.1 22.3 0.27 11.8 3.3 4.7 5 0 0 5 5 5 0 Zinc finger, C2H2 type Actin_micro PF17003.5 CDJ89643.1 - 5.9 6.0 8.1 0.33 10.1 1.6 2.1 2 0 0 2 2 2 0 Putative actin-like family adh_short_C2 PF13561.6 CDJ89644.1 - 1.5e-64 217.8 0.4 1.7e-64 217.6 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDJ89644.1 - 4.7e-48 163.2 1.4 6.1e-48 162.9 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDJ89644.1 - 1.6e-18 67.2 0.3 2.5e-18 66.6 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDJ89644.1 - 1.5e-06 27.8 0.1 2.1e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CDJ89644.1 - 4.7e-05 22.5 0.5 6.3e-05 22.1 0.5 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 CDJ89644.1 - 7.1e-05 23.1 0.1 0.00016 22.0 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 CDJ89644.1 - 0.0046 16.1 0.1 0.0066 15.6 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3HCDH_N PF02737.18 CDJ89644.1 - 0.018 14.9 0.1 0.041 13.8 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 CDJ89644.1 - 0.059 13.6 0.7 0.36 11.1 0.0 2.3 2 1 1 3 3 3 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 CDJ89644.1 - 0.16 11.3 0.6 1.8 7.9 0.0 2.6 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Antimicrobial_2 PF08023.12 CDJ89644.1 - 1 9.9 3.7 7.3 7.2 0.4 3.4 3 0 0 3 3 3 0 Frog antimicrobial peptide RVT_1 PF00078.27 CDJ89645.1 - 4.2e-26 91.8 0.0 6e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_M14 PF00246.24 CDJ89646.1 - 3.3e-74 250.3 0.1 4.4e-74 249.9 0.1 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase CarbopepD_reg_2 PF13715.6 CDJ89646.1 - 1.2e-06 28.4 0.0 2.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 CarboxypepD_reg-like domain AstE_AspA PF04952.14 CDJ89646.1 - 0.0074 15.4 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family MetallophosN PF16371.5 CDJ89646.1 - 0.029 14.6 0.1 2.9 8.2 0.1 2.4 2 0 0 2 2 2 0 N terminal of Calcineurin-like phosphoesterase Sugar_tr PF00083.24 CDJ89647.1 - 1.3e-53 182.4 19.4 1.5e-53 182.3 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ89647.1 - 9.4e-20 70.8 25.5 9.4e-20 70.8 25.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Chromo PF00385.24 CDJ89649.1 - 0.00018 21.4 0.2 0.00034 20.5 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Laminin_G_2 PF02210.24 CDJ89651.1 - 1.3e-22 80.7 0.0 1.2e-19 71.1 0.0 2.5 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 CDJ89651.1 - 2e-19 70.1 0.0 8.7e-17 61.6 0.0 2.7 2 1 0 2 2 2 2 Laminin G domain Cadherin_C PF01049.17 CDJ89651.1 - 3.6e-12 46.8 0.0 6.3e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin PF00028.17 CDJ89651.1 - 2e-09 37.8 0.0 2.5e-07 31.0 0.0 3.3 3 0 0 3 3 3 1 Cadherin domain DUF4625 PF15418.6 CDJ89651.1 - 0.06 13.6 0.2 0.62 10.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4625) EGF PF00008.27 CDJ89651.1 - 0.15 12.4 30.1 0.16 12.3 1.5 4.3 4 0 0 4 4 4 0 EGF-like domain hEGF PF12661.7 CDJ89651.1 - 1.1 10.0 38.0 0.028 15.0 2.9 4.9 5 0 0 5 5 5 0 Human growth factor-like EGF Peptidase_C1 PF00112.23 CDJ89652.1 - 1.9e-47 162.2 10.1 2.5e-47 161.8 10.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ89652.1 - 0.5 9.1 3.6 0.63 8.8 1.4 1.9 2 0 0 2 2 2 0 Peptidase C1-like family Tam41_Mmp37 PF09139.11 CDJ89653.1 - 8.4e-79 265.3 0.3 5.5e-47 160.8 0.1 2.0 1 1 1 2 2 2 2 Phosphatidate cytidylyltransferase, mitochondrial E3_UFM1_ligase PF09743.9 CDJ89653.1 - 0.024 14.3 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 E3 UFM1-protein ligase 1 TP53IP5 PF15331.6 CDJ89654.1 - 0.0056 16.8 1.9 0.0079 16.4 1.9 1.2 1 0 0 1 1 1 1 Cellular tumour antigen p53-inducible 5 Phage_cap_E PF03864.15 CDJ89654.1 - 0.12 11.5 3.2 4.3 6.4 0.0 2.0 2 0 0 2 2 2 0 Phage major capsid protein E UPF0149 PF03695.13 CDJ89654.1 - 0.13 12.5 1.5 0.22 11.8 1.3 1.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0149) ApoO PF09769.9 CDJ89654.1 - 0.16 11.9 0.2 0.31 11.0 0.2 1.4 1 0 0 1 1 1 0 Apolipoprotein O KIP1 PF07765.12 CDJ89654.1 - 0.17 12.0 2.5 0.36 11.0 2.5 1.6 1 0 0 1 1 1 0 KIP1-like protein PDEase_I PF00233.19 CDJ89655.1 - 1.4e-70 237.7 6.0 1.4e-70 237.7 6.0 1.9 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 CDJ89655.1 - 1.1e-16 61.6 0.0 2.1e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 CDJ89655.1 - 6.4e-08 33.0 0.0 1.3e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 CDJ89655.1 - 5.4e-05 23.5 0.0 0.00014 22.2 0.0 1.8 1 1 0 1 1 1 1 GAF domain SpoVT_C PF15714.5 CDJ89655.1 - 0.00087 19.3 0.0 0.0062 16.6 0.0 2.3 2 0 0 2 2 2 1 Stage V sporulation protein T C-terminal, transcription factor FA_FANCE PF11510.8 CDJ89655.1 - 0.083 12.2 0.2 0.14 11.5 0.2 1.3 1 0 0 1 1 1 0 Fanconi Anaemia group E protein FANCE PDZ_5 PF17817.1 CDJ89656.1 - 9.9e-15 54.6 1.0 3.2e-14 53.0 1.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CDJ89656.1 - 8e-12 45.3 0.2 2e-11 44.1 0.2 1.7 1 0 0 1 1 1 1 PDZ domain SAM_2 PF07647.17 CDJ89656.1 - 2.5e-10 40.3 0.1 5e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CDJ89656.1 - 8.8e-08 32.5 0.2 1.8e-07 31.5 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CREPT PF16566.5 CDJ89656.1 - 0.027 14.7 16.0 0.042 14.0 14.9 1.8 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour PDZ_6 PF17820.1 CDJ89656.1 - 0.029 14.2 2.2 0.13 12.2 0.3 2.9 2 1 1 3 3 3 0 PDZ domain Spc7 PF08317.11 CDJ89656.1 - 0.15 11.0 21.1 0.37 9.6 21.1 1.7 1 0 0 1 1 1 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 CDJ89656.1 - 0.16 12.3 13.3 0.19 12.1 11.4 2.2 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3584 PF12128.8 CDJ89656.1 - 0.17 9.3 18.6 0.27 8.7 18.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.15 CDJ89656.1 - 0.32 10.5 13.0 0.04 13.5 8.5 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit BshC PF10079.9 CDJ89656.1 - 0.53 9.0 10.5 0.89 8.2 10.5 1.4 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC DUF4407 PF14362.6 CDJ89656.1 - 0.56 9.5 9.2 1.5 8.1 9.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATG16 PF08614.11 CDJ89656.1 - 0.66 10.2 30.0 0.26 11.5 22.2 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) VSG_B PF13206.6 CDJ89656.1 - 3.2 6.9 7.3 6.4 5.9 7.3 1.5 1 0 0 1 1 1 0 Trypanosomal VSG domain GTP-bdg_M PF16360.5 CDJ89656.1 - 4.4 8.0 14.7 12 6.5 1.3 4.2 3 1 0 3 3 3 0 GTP-binding GTPase Middle Region DUF2802 PF10975.8 CDJ89656.1 - 4.7 7.4 11.9 4.5 7.5 2.7 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2802) PDEase_I PF00233.19 CDJ89657.1 - 8.4e-71 238.5 6.0 8.4e-71 238.5 6.0 1.9 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 CDJ89657.1 - 7.8e-13 49.2 0.0 1.6e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 CDJ89657.1 - 3.8e-06 27.2 0.0 8e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 GAF domain SpoVT_C PF15714.5 CDJ89657.1 - 0.00072 19.6 0.0 0.0061 16.6 0.0 2.3 2 0 0 2 2 2 1 Stage V sporulation protein T C-terminal, transcription factor GAF_3 PF13492.6 CDJ89657.1 - 0.05 14.0 0.0 0.098 13.0 0.0 1.5 1 0 0 1 1 1 0 GAF domain FA_FANCE PF11510.8 CDJ89657.1 - 0.063 12.6 0.2 0.1 12.0 0.2 1.3 1 0 0 1 1 1 0 Fanconi Anaemia group E protein FANCE PDZ_5 PF17817.1 CDJ89658.1 - 1.2e-21 76.7 0.1 3.7e-21 75.2 0.1 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CDJ89658.1 - 8.2e-12 45.3 0.2 2e-11 44.1 0.2 1.7 1 0 0 1 1 1 1 PDZ domain SAM_2 PF07647.17 CDJ89658.1 - 2.5e-10 40.3 0.1 5.1e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CDJ89658.1 - 8.9e-08 32.5 0.2 1.9e-07 31.4 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CREPT PF16566.5 CDJ89658.1 - 0.027 14.6 16.0 0.043 14.0 14.9 1.8 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour PDZ_6 PF17820.1 CDJ89658.1 - 0.03 14.2 2.2 0.13 12.2 0.3 2.8 2 1 1 3 3 3 0 PDZ domain Spc7 PF08317.11 CDJ89658.1 - 0.15 10.9 21.1 0.38 9.6 21.1 1.7 1 0 0 1 1 1 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 CDJ89658.1 - 0.17 12.2 13.3 0.19 12.0 11.4 2.2 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3584 PF12128.8 CDJ89658.1 - 0.18 9.3 18.6 0.28 8.7 18.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.15 CDJ89658.1 - 0.3 10.6 12.9 0.037 13.6 8.3 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit BshC PF10079.9 CDJ89658.1 - 0.54 8.9 10.5 0.91 8.2 10.5 1.4 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC DUF4407 PF14362.6 CDJ89658.1 - 0.58 9.5 9.2 1.5 8.1 9.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATG16 PF08614.11 CDJ89658.1 - 0.69 10.1 30.0 0.11 12.8 20.4 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Uds1 PF15456.6 CDJ89658.1 - 1.2 9.4 23.9 2 8.6 12.1 3.7 2 1 1 3 3 3 0 Up-regulated During Septation VSG_B PF13206.6 CDJ89658.1 - 3.3 6.9 7.3 6.5 5.9 7.3 1.5 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF2802 PF10975.8 CDJ89658.1 - 4.9 7.4 11.9 4.6 7.4 2.7 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2802) GTP-bdg_M PF16360.5 CDJ89658.1 - 4.9 7.8 14.7 13 6.5 1.3 4.2 3 1 0 3 3 3 0 GTP-binding GTPase Middle Region DUF3450 PF11932.8 CDJ89658.1 - 9.9 5.4 16.2 16 4.7 14.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FARP PF01581.16 CDJ89659.1 - 0.026 14.9 6.4 3.3 8.6 0.5 2.9 2 0 0 2 2 2 0 FMRFamide related peptide family Med13_N PF11597.8 CDJ89659.1 - 0.22 10.9 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal SCVP PF17619.2 CDJ89660.1 - 2.4e-11 44.4 0.0 2.6e-11 44.2 0.0 1.0 1 0 0 1 1 1 1 Secreted clade V proteins zf-C2H2_4 PF13894.6 CDJ89662.1 - 8.7e-07 29.3 26.6 0.032 15.0 0.5 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-Di19 PF05605.12 CDJ89662.1 - 3.8e-06 27.1 12.7 3.4e-05 24.0 4.5 3.2 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 CDJ89662.1 - 7.4e-05 22.4 1.3 7.4e-05 22.4 1.3 4.3 5 0 0 5 5 5 1 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 CDJ89662.1 - 0.00017 21.8 19.2 0.028 14.9 0.1 4.8 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 CDJ89662.1 - 0.00019 21.7 25.8 0.036 14.5 0.8 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-met PF12874.7 CDJ89662.1 - 0.0012 19.2 11.0 0.0047 17.3 0.8 3.6 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDJ89662.1 - 0.012 15.9 10.0 0.94 9.8 0.1 3.7 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF629 PF04780.12 CDJ89662.1 - 0.044 12.3 4.5 0.24 9.9 0.5 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.7 CDJ89662.1 - 0.19 12.1 0.1 0.19 12.1 0.1 3.6 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 CDJ89662.1 - 1.9 8.2 9.8 0.34 10.6 0.4 2.8 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_11 PF16622.5 CDJ89662.1 - 2.1 8.2 6.1 2.4 8.0 0.7 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type DUF4379 PF14311.6 CDJ89662.1 - 2.2 8.7 7.7 12 6.4 0.9 2.7 2 1 0 2 2 2 0 Probable Zinc-ribbon domain Zn_ribbon_SprT PF17283.2 CDJ89662.1 - 4 7.4 9.7 15 5.6 3.8 2.6 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Pkinase PF00069.25 CDJ89663.1 - 2.3e-59 200.9 0.2 2.8e-59 200.6 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ89663.1 - 6.6e-37 127.2 0.1 9.4e-37 126.7 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ89663.1 - 5.4e-08 32.5 0.0 9.4e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CDJ89663.1 - 9.8e-05 21.3 0.0 0.0002 20.3 0.0 1.6 1 1 0 1 1 1 1 Fungal protein kinase Peptidase_S32 PF05579.13 CDJ89663.1 - 0.03 13.5 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 EB1 PF03271.17 CDJ89664.1 - 9e-12 45.0 0.2 1.8e-11 44.1 0.2 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 CDJ89664.1 - 1.5e-07 31.5 0.4 2.7e-07 30.7 0.4 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Cep57_CLD_2 PF14197.6 CDJ89664.1 - 6.5e-05 22.9 0.6 0.00011 22.2 0.6 1.3 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 DUF5102 PF17104.5 CDJ89664.1 - 0.014 15.4 0.5 0.02 14.9 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) FAM76 PF16046.5 CDJ89664.1 - 0.015 14.7 0.1 0.021 14.2 0.1 1.1 1 0 0 1 1 1 0 FAM76 protein End3 PF12761.7 CDJ89664.1 - 0.027 14.7 0.1 0.039 14.1 0.1 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 ATG16 PF08614.11 CDJ89664.1 - 0.14 12.3 1.7 0.2 11.8 1.7 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) zf-C4H2 PF10146.9 CDJ89664.1 - 5.9 7.1 7.1 0.69 10.2 0.3 2.0 1 1 0 2 2 2 0 Zinc finger-containing protein LSM PF01423.22 CDJ89665.1 - 1e-21 76.3 0.3 1.2e-21 76.2 0.3 1.0 1 0 0 1 1 1 1 LSM domain ASPRs PF17641.2 CDJ89667.1 - 0.048 13.9 0.1 0.059 13.7 0.1 1.1 1 0 0 1 1 1 0 Ancylostoma-associated secreted protein related AMP-binding PF00501.28 CDJ89668.1 - 2.7e-102 342.5 0.0 3.5e-102 342.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ89668.1 - 8.1e-15 55.6 0.0 2.4e-14 54.0 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CC PF04942.14 CDJ89669.1 - 0.0043 17.2 10.4 0.0043 17.2 10.4 3.2 3 0 0 3 3 3 2 CC domain CC PF04942.14 CDJ89670.1 - 0.0084 16.3 9.5 0.0084 16.3 9.5 5.0 4 0 0 4 4 4 2 CC domain Myotub-related PF06602.14 CDJ89672.1 - 7.6e-134 446.1 0.2 1.1e-133 445.6 0.2 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain 6PF2K PF01591.18 CDJ89672.1 - 9.2e-86 286.7 0.4 1.5e-85 286.1 0.4 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CDJ89672.1 - 4.1e-42 144.1 0.0 7.5e-42 143.2 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) GRAM PF02893.20 CDJ89672.1 - 1.9e-07 31.0 0.0 4.3e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 GRAM domain DSPc PF00782.20 CDJ89672.1 - 1.3e-06 28.2 0.1 4.1e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain AAA_33 PF13671.6 CDJ89672.1 - 0.00011 22.4 0.0 0.0003 21.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Y_phosphatase PF00102.27 CDJ89672.1 - 0.0012 18.5 0.0 0.0039 16.8 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CDJ89672.1 - 0.0052 16.8 0.0 0.0089 16.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family 7TM_GPCR_Srx PF10328.9 CDJ89673.1 - 2e-14 53.9 23.5 2.4e-14 53.6 23.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF621 PF04789.15 CDJ89673.1 - 5.4e-07 29.1 18.9 7.5e-07 28.6 18.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF621) PDEase_I PF00233.19 CDJ89674.1 - 1.4e-70 237.7 6.0 1.4e-70 237.7 6.0 1.9 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 CDJ89674.1 - 1.1e-16 61.6 0.0 2.1e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 CDJ89674.1 - 6.4e-08 33.0 0.0 1.3e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 CDJ89674.1 - 5.4e-05 23.5 0.0 0.00014 22.2 0.0 1.8 1 1 0 1 1 1 1 GAF domain SpoVT_C PF15714.5 CDJ89674.1 - 0.00087 19.3 0.0 0.0062 16.6 0.0 2.3 2 0 0 2 2 2 1 Stage V sporulation protein T C-terminal, transcription factor FA_FANCE PF11510.8 CDJ89674.1 - 0.083 12.2 0.2 0.14 11.5 0.2 1.3 1 0 0 1 1 1 0 Fanconi Anaemia group E protein FANCE PDZ_5 PF17817.1 CDJ89675.1 - 1.2e-21 76.7 0.1 3.7e-21 75.2 0.1 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CDJ89675.1 - 8.2e-12 45.3 0.2 2e-11 44.1 0.2 1.7 1 0 0 1 1 1 1 PDZ domain SAM_2 PF07647.17 CDJ89675.1 - 2.5e-10 40.3 0.1 5.1e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CDJ89675.1 - 8.9e-08 32.5 0.2 1.9e-07 31.4 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CREPT PF16566.5 CDJ89675.1 - 0.027 14.6 16.0 0.043 14.0 14.9 1.8 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour PDZ_6 PF17820.1 CDJ89675.1 - 0.03 14.2 2.2 0.13 12.2 0.3 2.8 2 1 1 3 3 3 0 PDZ domain Spc7 PF08317.11 CDJ89675.1 - 0.15 10.9 21.1 0.38 9.6 21.1 1.7 1 0 0 1 1 1 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 CDJ89675.1 - 0.17 12.2 13.3 0.19 12.0 11.4 2.2 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3584 PF12128.8 CDJ89675.1 - 0.18 9.3 18.6 0.28 8.7 18.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.15 CDJ89675.1 - 0.3 10.6 12.9 0.037 13.6 8.3 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit BshC PF10079.9 CDJ89675.1 - 0.54 8.9 10.5 0.91 8.2 10.5 1.4 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC DUF4407 PF14362.6 CDJ89675.1 - 0.58 9.5 9.2 1.5 8.1 9.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATG16 PF08614.11 CDJ89675.1 - 0.69 10.1 30.0 0.11 12.8 20.4 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Uds1 PF15456.6 CDJ89675.1 - 1.2 9.4 23.9 2 8.6 12.1 3.7 2 1 1 3 3 3 0 Up-regulated During Septation VSG_B PF13206.6 CDJ89675.1 - 3.3 6.9 7.3 6.5 5.9 7.3 1.5 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF2802 PF10975.8 CDJ89675.1 - 4.9 7.4 11.9 4.6 7.4 2.7 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2802) GTP-bdg_M PF16360.5 CDJ89675.1 - 4.9 7.8 14.7 13 6.5 1.3 4.2 3 1 0 3 3 3 0 GTP-binding GTPase Middle Region DUF3450 PF11932.8 CDJ89675.1 - 9.9 5.4 16.2 16 4.7 14.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) KH_1 PF00013.29 CDJ89676.1 - 5.8e-108 352.8 27.0 3.6e-16 58.7 1.6 9.3 9 0 0 9 9 9 9 KH domain SLS PF14611.6 CDJ89676.1 - 1.9e-16 60.6 13.6 3.6e-05 23.7 1.0 6.0 1 1 2 5 5 5 4 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 CDJ89676.1 - 3.5e-08 33.1 23.9 0.02 14.7 4.4 7.1 6 2 0 6 6 6 3 KH domain YbbR PF07949.12 CDJ89676.1 - 2.5e-05 24.5 15.8 0.95 9.9 0.1 6.1 6 0 0 6 6 6 3 YbbR-like protein DUF4974 PF16344.5 CDJ89676.1 - 0.0035 17.3 5.9 0.047 13.7 0.0 4.9 6 0 0 6 6 6 1 Domain of unknown function (DUF4974) KH_5 PF13184.6 CDJ89676.1 - 0.013 15.6 13.9 2.7 8.1 0.4 6.0 6 0 0 6 6 6 0 NusA-like KH domain KAsynt_C_assoc PF16197.5 CDJ89676.1 - 0.037 14.5 0.0 48 4.5 0.0 3.8 3 1 1 4 4 4 0 Ketoacyl-synthetase C-terminal extension DUF2856 PF11043.8 CDJ89676.1 - 0.069 13.3 1.8 3.2 7.9 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2856) KH_4 PF13083.6 CDJ89676.1 - 0.098 12.5 0.0 0.098 12.5 0.0 5.8 7 1 0 7 7 7 0 KH domain QIL1 PF15884.5 CDJ89676.1 - 0.54 10.9 1.7 56 4.4 0.1 3.9 4 0 0 4 4 4 0 MICOS complex subunit MIC13, QIL1 ZapA PF05164.13 CDJ89676.1 - 0.66 10.5 5.2 6.8 7.2 0.1 4.1 4 0 0 4 4 4 0 Cell division protein ZapA DUF4041 PF13250.6 CDJ89676.1 - 1.9 8.4 4.9 4.2 7.3 0.1 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4041) DUF2229 PF09989.9 CDJ89676.1 - 2.2 7.9 4.1 4.8 6.8 0.1 2.6 3 0 0 3 3 3 0 CoA enzyme activase uncharacterised domain (DUF2229) YqgF PF14639.6 CDJ89676.1 - 3.7 7.3 12.8 1.9 8.3 0.1 5.2 7 0 0 7 7 7 0 Holliday-junction resolvase-like of SPT6 Pepsin-I3 PF06394.13 CDJ89677.1 - 1.6e-56 188.4 7.0 9.5e-32 109.0 1.5 2.1 2 0 0 2 2 2 2 Pepsin inhibitor-3-like repeated domain DUF3987 PF13148.6 CDJ89677.1 - 5.4e-06 25.7 4.0 0.0017 17.5 4.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) KapB PF08810.10 CDJ89677.1 - 0.00011 22.4 2.3 0.002 18.3 0.5 2.1 2 0 0 2 2 2 1 Kinase associated protein B YbjQ_1 PF01906.17 CDJ89677.1 - 0.058 14.0 0.3 7.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Putative heavy-metal-binding Bacillus_HBL PF05791.11 CDJ89677.1 - 0.069 13.0 2.8 1.1 9.1 0.2 2.1 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) UBN_AB PF14075.6 CDJ89677.1 - 4.2 7.0 8.1 12 5.5 8.1 1.7 1 1 0 1 1 1 0 Ubinuclein conserved middle domain SieB PF14163.6 CDJ89678.1 - 0.02 14.4 0.3 0.033 13.7 0.3 1.3 1 0 0 1 1 1 0 Super-infection exclusion protein B LapA_dom PF06305.11 CDJ89678.1 - 0.076 12.8 0.2 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Lzipper-MIP1 PF14389.6 CDJ89678.1 - 0.11 12.8 0.9 1.2 9.5 0.1 2.3 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Gemini_mov PF01708.16 CDJ89678.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Geminivirus putative movement protein DUF948 PF06103.11 CDJ89678.1 - 3 8.2 5.0 15 5.9 5.0 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Ground-like PF04155.18 CDJ89679.1 - 5.9e-14 52.5 0.1 8.1e-14 52.0 0.1 1.2 1 0 0 1 1 1 1 Ground-like domain Toxin_YhaV PF11663.8 CDJ89679.1 - 0.079 13.0 0.0 0.097 12.7 0.0 1.1 1 0 0 1 1 1 0 Toxin with endonuclease activity, of toxin-antitoxin system Peptidase_C69 PF03577.15 CDJ89679.1 - 0.18 10.7 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C69 7TM_GPCR_Srab PF10292.9 CDJ89680.1 - 5.1e-11 42.1 19.3 6.4e-11 41.7 19.3 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor Sre PF03125.18 CDJ89680.1 - 1.7e-06 27.5 26.1 9.2e-05 21.7 26.0 2.9 1 1 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor 7tm_1 PF00001.21 CDJ89680.1 - 0.21 10.9 16.3 0.28 10.4 16.3 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) F-box-like PF12937.7 CDJ89681.1 - 1.4e-07 31.3 0.4 3.9e-07 29.8 0.4 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 CDJ89681.1 - 6.2e-05 23.3 10.0 0.0015 18.9 2.7 5.2 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) F-box PF00646.33 CDJ89681.1 - 8.7e-05 22.3 0.2 0.00045 20.0 0.2 2.2 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.6 CDJ89681.1 - 0.00018 21.3 9.3 0.32 11.1 0.0 6.4 7 0 0 7 7 7 1 Leucine Rich repeat LRR_8 PF13855.6 CDJ89681.1 - 0.0019 17.9 7.8 0.0021 17.8 0.4 3.7 4 1 1 5 5 5 1 Leucine rich repeat LRR_1 PF00560.33 CDJ89681.1 - 0.01 16.2 14.5 2.1 9.2 0.4 5.8 5 2 0 5 5 5 0 Leucine Rich Repeat Ribosomal_L29 PF00831.23 CDJ89682.1 - 1.8e-15 56.6 0.5 1.8e-15 56.6 0.5 2.5 2 1 1 3 3 3 1 Ribosomal L29 protein Snapin_Pallidin PF14712.6 CDJ89682.1 - 0.062 13.7 8.9 0.14 12.6 2.1 2.1 1 1 1 2 2 2 0 Snapin/Pallidin HTH_ABP1_N PF18107.1 CDJ89682.1 - 0.67 9.7 5.4 0.17 11.6 0.9 2.1 1 1 1 2 2 2 0 Fission yeast centromere protein N-terminal domain Claudin_2 PF13903.6 CDJ89683.1 - 0.0017 18.2 2.0 0.002 17.9 2.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4870 PF09685.10 CDJ89683.1 - 0.012 15.7 3.5 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) PMP22_Claudin PF00822.20 CDJ89683.1 - 0.013 15.3 1.2 0.026 14.4 0.9 1.6 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family SUR7 PF06687.12 CDJ89683.1 - 0.091 12.4 2.9 0.045 13.4 1.1 1.4 1 1 0 1 1 1 0 SUR7/PalI family FARP PF01581.16 CDJ89684.1 - 0.0033 17.6 5.9 17 6.5 0.2 3.7 3 0 0 3 3 3 3 FMRFamide related peptide family RFamide_26RFa PF11109.8 CDJ89684.1 - 0.046 14.2 0.1 0.051 14.1 0.1 1.0 1 0 0 1 1 1 0 Orexigenic neuropeptide Qrfp/P518 PDZ_6 PF17820.1 CDJ89685.1 - 6.2e-06 26.0 0.8 1.1e-05 25.2 0.8 1.4 1 0 0 1 1 1 1 PDZ domain DUF4749 PF15936.5 CDJ89685.1 - 2.2e-05 25.5 0.2 3.6e-05 24.8 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4749) PDZ PF00595.24 CDJ89685.1 - 0.0018 18.6 0.1 0.0029 17.9 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ89685.1 - 0.016 15.6 0.7 0.038 14.3 0.6 1.8 1 1 0 1 1 1 0 PDZ domain Ripply PF14998.6 CDJ89685.1 - 0.031 14.9 0.0 0.046 14.4 0.0 1.2 1 0 0 1 1 1 0 Transcription Regulator DUF874 PF05917.11 CDJ89687.1 - 0.056 12.5 4.9 0.097 11.7 4.9 1.3 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) DUF4370 PF14290.6 CDJ89688.1 - 0.05 13.5 0.1 0.065 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4370) ASPRs PF17641.2 CDJ89689.1 - 0.019 15.2 0.1 0.023 15.0 0.1 1.1 1 0 0 1 1 1 0 Ancylostoma-associated secreted protein related Rhomboid PF01694.22 CDJ89690.1 - 1.4e-36 125.8 8.2 1.4e-36 125.8 8.2 1.8 3 0 0 3 3 3 1 Rhomboid family EF-hand_7 PF13499.6 CDJ89690.1 - 6.2e-06 26.6 0.1 9.6e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair DUF998 PF06197.13 CDJ89690.1 - 3.6e-05 23.4 5.7 3.6e-05 23.4 5.7 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF998) EF-hand_1 PF00036.32 CDJ89690.1 - 0.00011 21.5 0.0 0.00022 20.5 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 CDJ89690.1 - 0.00057 19.7 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 CDJ89690.1 - 0.0025 17.2 0.1 0.0045 16.4 0.1 1.4 1 0 0 1 1 1 1 EF hand MtrE PF04206.12 CDJ89690.1 - 0.02 14.2 0.5 0.047 13.0 0.5 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit E EF-hand_6 PF13405.6 CDJ89690.1 - 0.19 11.7 0.0 0.52 10.4 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain Recep_L_domain PF01030.24 CDJ89691.1 - 3.6e-24 85.0 4.3 2.3e-08 34.1 0.0 3.7 3 0 0 3 3 3 3 Receptor L domain Amelogenin PF02948.15 CDJ89693.1 - 0.00028 21.6 8.6 0.00047 20.9 8.6 1.3 1 0 0 1 1 1 1 Amelogenin PGM1_C PF18105.1 CDJ89693.1 - 0.13 11.8 2.4 0.22 11.1 2.4 1.4 1 0 0 1 1 1 0 PGM1 C-terminal domain Recep_L_domain PF01030.24 CDJ89694.1 - 6.1e-12 45.6 0.1 9.3e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 Receptor L domain TMEM154 PF15102.6 CDJ89694.1 - 0.0075 16.2 1.2 0.017 15.0 0.7 1.8 2 0 0 2 2 2 1 TMEM154 protein family Syndecan PF01034.20 CDJ89694.1 - 0.026 14.4 0.7 0.026 14.4 0.7 1.7 2 0 0 2 2 2 0 Syndecan domain CD34_antigen PF06365.12 CDJ89694.1 - 0.068 12.7 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family LAX PF15681.5 CDJ89694.1 - 0.084 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Lymphocyte activation family X EphA2_TM PF14575.6 CDJ89694.1 - 0.11 13.4 0.0 0.37 11.7 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Tmemb_9 PF05434.11 CDJ89694.1 - 0.14 12.1 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 TMEM9 Recep_L_domain PF01030.24 CDJ89695.1 - 7.4e-10 38.9 0.3 1.1e-09 38.4 0.3 1.2 1 0 0 1 1 1 1 Receptor L domain EphA2_TM PF14575.6 CDJ89695.1 - 0.0029 18.5 0.1 0.0068 17.3 0.1 1.7 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 CDJ89695.1 - 0.0096 15.8 0.5 0.019 14.8 0.1 1.8 2 0 0 2 2 2 1 TMEM154 protein family Orf78 PF06024.12 CDJ89695.1 - 0.016 15.5 0.0 0.016 15.5 0.0 2.1 2 0 0 2 2 2 0 Orf78 (ac78) Glycophorin_A PF01102.18 CDJ89695.1 - 0.042 14.1 1.8 0.066 13.4 0.9 1.8 1 1 1 2 2 2 0 Glycophorin A CD34_antigen PF06365.12 CDJ89695.1 - 0.059 12.9 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family V_ATPase_I PF01496.19 CDJ89695.1 - 0.11 10.3 0.1 0.15 9.9 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PRIMA1 PF16101.5 CDJ89695.1 - 0.12 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 OSTbeta PF15048.6 CDJ89695.1 - 0.15 12.2 1.3 0.56 10.4 1.3 2.0 1 1 0 1 1 1 0 Organic solute transporter subunit beta protein DUF4834 PF16118.5 CDJ89695.1 - 0.17 12.8 1.0 0.49 11.4 1.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Herpes_gE PF02480.16 CDJ89695.1 - 0.19 10.5 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4736 PF15883.5 CDJ89695.1 - 0.22 11.2 0.0 0.35 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) DUF5305 PF17231.2 CDJ89695.1 - 0.32 10.4 0.1 0.32 10.4 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5305) FAM176 PF14851.6 CDJ89695.1 - 0.36 10.5 3.1 0.56 9.9 0.0 2.2 1 1 1 2 2 2 0 FAM176 family Baculo_11_kDa PF06143.11 CDJ89695.1 - 0.74 9.4 2.8 1.3 8.6 2.8 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Pre-SET PF05033.16 CDJ89697.1 - 9.3e-08 32.7 0.6 1.1e-07 32.4 0.6 1.1 1 0 0 1 1 1 1 Pre-SET motif RVT_1 PF00078.27 CDJ89698.1 - 0.0038 16.8 0.0 0.012 15.1 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1677 PF07911.13 CDJ89698.1 - 0.056 13.8 0.2 0.13 12.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) DUF4423 PF14394.6 CDJ89698.1 - 0.069 12.9 1.2 0.13 12.0 1.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4423) FHIPEP PF00771.20 CDJ89698.1 - 0.17 10.3 0.1 0.21 10.0 0.1 1.1 1 0 0 1 1 1 0 FHIPEP family DUF4615 PF15393.6 CDJ89698.1 - 0.22 12.1 1.6 0.44 11.1 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) eIF-1a PF01176.19 CDJ89699.1 - 1.3e-33 114.6 8.5 8.5e-19 67.1 0.8 3.5 3 0 0 3 3 3 3 Translation initiation factor 1A / IF-1 Rhabdo_M2 PF04785.12 CDJ89699.1 - 0.0068 15.7 0.1 1.3 8.3 0.0 2.8 3 0 0 3 3 3 2 Rhabdovirus matrix protein M2 CDC48_N PF02359.18 CDJ89699.1 - 0.023 14.9 0.1 0.078 13.2 0.1 1.9 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain Laterosporulin PF17861.1 CDJ89699.1 - 0.26 11.7 1.7 17 5.9 0.1 3.0 3 0 0 3 3 3 0 Laterosporulin defensin-like peptide RsgA_N PF16745.5 CDJ89699.1 - 0.57 10.0 5.9 0.15 11.8 1.2 2.3 2 0 0 2 2 2 0 RsgA N-terminal domain DnaJ PF00226.31 CDJ89700.1 - 7.3e-06 26.0 0.0 1.8e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain TUDOR PF00567.24 CDJ89701.1 - 0.0086 16.1 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Tudor domain HSP20 PF00011.21 CDJ89703.1 - 7e-13 48.6 0.0 1.1e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Hjc PF01870.18 CDJ89703.1 - 0.04 13.9 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) PapA_C PF16911.5 CDJ89703.1 - 0.17 12.0 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus Ion_trans PF00520.31 CDJ89704.1 - 1.1e-71 241.0 6.4 1.3e-71 240.7 6.4 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 CDJ89704.1 - 4.6e-05 22.3 16.8 0.0059 15.3 2.5 3.1 2 1 1 3 3 3 3 Polycystin cation channel SieB PF14163.6 CDJ89704.1 - 0.026 14.0 0.3 0.46 10.0 0.0 2.5 2 0 0 2 2 2 0 Super-infection exclusion protein B Chordopox_A13L PF05961.11 CDJ89704.1 - 5.3 7.3 5.3 1.3 9.3 0.1 2.7 3 0 0 3 3 3 0 Chordopoxvirus A13L protein HTH_48 PF17906.1 CDJ89706.1 - 6.5e-11 42.2 0.2 1e-10 41.6 0.2 1.3 1 0 0 1 1 1 1 HTH domain in Mos1 transposase Transposase_1 PF01359.18 CDJ89706.1 - 5.2e-06 26.2 2.5 8.7e-06 25.5 0.0 2.4 3 0 0 3 3 3 1 Transposase (partial DDE domain) HTH_Tnp_Tc3_2 PF01498.18 CDJ89706.1 - 0.00056 20.1 0.0 0.001 19.3 0.0 1.4 1 0 0 1 1 1 1 Transposase HTH_11 PF08279.12 CDJ89706.1 - 0.0027 17.6 0.0 0.0062 16.4 0.0 1.6 1 0 0 1 1 1 1 HTH domain GerE PF00196.19 CDJ89706.1 - 0.0032 17.0 0.0 0.0065 16.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_24 PF13412.6 CDJ89706.1 - 0.0033 17.0 0.0 0.0066 16.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 CDJ89706.1 - 0.049 13.3 0.0 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_AsnC-type PF13404.6 CDJ89706.1 - 0.061 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_Tnp_IS630 PF01710.16 CDJ89706.1 - 0.078 13.0 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Transposase Sarcoglycan_1 PF04790.13 CDJ89707.1 - 1.8e-64 217.6 0.0 2.1e-64 217.4 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.9 CDJ89707.1 - 0.0042 17.0 0.0 0.019 14.8 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2345) RT_RNaseH PF17917.1 CDJ89709.1 - 0.0032 17.7 0.0 0.005 17.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase MIP PF00230.20 CDJ89711.1 - 2.8e-18 66.5 0.7 3.3e-18 66.2 0.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein Histone PF00125.24 CDJ89712.1 - 2.3e-24 86.3 0.3 2.8e-24 85.9 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Alk_phosphatase PF00245.20 CDJ89712.1 - 0.17 10.8 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Alkaline phosphatase DUF1011 PF06237.12 CDJ89713.1 - 2.1e-24 85.7 12.0 2.1e-24 85.7 12.0 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF1011) PAP_assoc PF03828.19 CDJ89714.1 - 1.8e-13 50.4 0.2 6.1e-13 48.8 0.2 2.0 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CDJ89714.1 - 0.013 15.7 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain Astacin PF01400.24 CDJ89715.1 - 0.0056 16.3 0.0 0.0088 15.7 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Astacin PF01400.24 CDJ89716.1 - 6.6e-18 65.0 3.5 1.5e-10 41.0 0.2 2.2 1 1 1 2 2 2 2 Astacin (Peptidase family M12A) DUF5478 PF17572.2 CDJ89716.1 - 0.088 12.9 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5478) Reprolysin_3 PF13582.6 CDJ89716.1 - 0.19 12.3 1.3 1 9.9 1.2 2.0 1 1 1 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DDE_3 PF13358.6 CDJ89717.1 - 8.1e-07 28.9 0.1 1.4e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease CUT PF02376.15 CDJ89718.1 - 3.1e-32 110.5 0.1 5e-32 109.9 0.1 1.3 1 0 0 1 1 1 1 CUT domain Homeodomain PF00046.29 CDJ89718.1 - 5.4e-11 42.2 0.4 1.2e-10 41.0 0.4 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ89718.1 - 0.0012 18.7 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain Patatin PF01734.22 CDJ89720.1 - 1.9e-15 57.6 0.2 6.2e-15 55.9 0.2 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase RAI16-like PF10257.9 CDJ89721.1 - 2.1e-51 174.9 8.0 3.9e-51 174.0 8.0 1.5 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Sigma54_CBD PF04963.13 CDJ89721.1 - 0.13 12.1 1.1 11 5.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 factor, core binding domain DUF1459 PF07312.11 CDJ89723.1 - 3.5e-08 33.6 4.6 4.1e-08 33.3 4.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1459) Rep_fac_C PF08542.11 CDJ89724.1 - 3.6e-19 68.9 0.0 2e-17 63.3 0.0 2.7 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 CDJ89724.1 - 1.3e-17 64.4 0.1 3.9e-17 62.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CDJ89724.1 - 3.1e-16 59.6 0.0 2.1e-14 53.7 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 CDJ89724.1 - 1.2e-08 35.1 0.1 1.4e-07 31.6 0.1 2.2 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 CDJ89724.1 - 4.7e-06 26.8 0.2 2.5e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 AAA C-terminal domain RuvB_N PF05496.12 CDJ89724.1 - 1.6e-05 24.7 0.0 4.5e-05 23.3 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 CDJ89724.1 - 2.8e-05 23.9 0.0 4.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CDJ89724.1 - 0.00011 22.0 0.6 0.027 14.2 0.1 2.5 1 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_11 PF13086.6 CDJ89724.1 - 0.00013 21.8 0.1 0.00042 20.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDJ89724.1 - 0.00013 22.2 0.2 0.0096 16.2 0.2 2.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 CDJ89724.1 - 0.00014 21.1 0.0 0.00024 20.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 CDJ89724.1 - 0.00016 21.5 0.0 0.00041 20.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 CDJ89724.1 - 0.00029 20.7 0.1 0.00044 20.1 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 CDJ89724.1 - 0.0004 20.4 0.0 0.00076 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ89724.1 - 0.00078 19.9 0.0 0.0019 18.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 CDJ89724.1 - 0.0015 18.9 0.8 0.027 14.8 0.3 2.6 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.14 CDJ89724.1 - 0.0032 17.5 0.8 0.044 13.8 0.3 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TniB PF05621.11 CDJ89724.1 - 0.0052 16.2 0.0 0.16 11.3 0.0 2.7 3 0 0 3 3 3 1 Bacterial TniB protein DUF2075 PF09848.9 CDJ89724.1 - 0.0059 15.9 0.7 0.23 10.7 0.7 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 CDJ89724.1 - 0.0072 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region ATPase_2 PF01637.18 CDJ89724.1 - 0.0082 16.1 0.1 0.018 14.9 0.0 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea PhoH PF02562.16 CDJ89724.1 - 0.01 15.3 0.3 2.2 7.7 0.0 2.3 1 1 1 2 2 2 0 PhoH-like protein ResIII PF04851.15 CDJ89724.1 - 0.012 15.7 0.1 0.55 10.2 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit PIF1 PF05970.14 CDJ89724.1 - 0.021 14.0 0.3 0.41 9.8 0.3 2.2 1 1 0 1 1 1 0 PIF1-like helicase ABC_tran PF00005.27 CDJ89724.1 - 0.024 15.2 0.0 0.066 13.7 0.0 1.8 1 1 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.21 CDJ89724.1 - 0.026 13.9 0.0 0.45 9.9 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CDJ89724.1 - 0.04 13.8 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RPAP3_C PF13877.6 CDJ89724.1 - 0.065 13.8 0.0 8.8 6.9 0.0 3.2 3 1 1 4 4 2 0 Potential Monad-binding region of RPAP3 Viral_helicase1 PF01443.18 CDJ89724.1 - 0.08 12.7 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF3802 PF12290.8 CDJ89724.1 - 0.09 13.3 0.2 0.19 12.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) AAA_25 PF13481.6 CDJ89724.1 - 0.13 11.9 0.4 2.8 7.5 0.0 2.3 1 1 1 2 2 2 0 AAA domain KBP_C PF12309.8 CDJ89724.1 - 0.13 11.8 0.2 0.25 10.8 0.0 1.5 2 0 0 2 2 2 0 KIF-1 binding protein C terminal RNA_helicase PF00910.22 CDJ89724.1 - 0.13 12.7 0.0 0.27 11.6 0.0 1.7 1 1 0 1 1 1 0 RNA helicase Rad9 PF04139.13 CDJ89725.1 - 5.9e-45 153.7 10.4 7.3e-45 153.4 9.8 1.5 2 0 0 2 2 2 1 Rad9 Tim54 PF11711.8 CDJ89725.1 - 0.12 11.1 0.6 0.19 10.5 0.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 EMG1 PF03587.14 CDJ89726.1 - 3.8e-71 238.8 0.0 4.6e-71 238.5 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Zw10 PF06248.13 CDJ89726.1 - 0.11 11.0 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 DHHC PF01529.20 CDJ89727.1 - 4.3e-38 130.5 16.8 4.3e-38 130.5 16.8 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Asp PF00026.23 CDJ89728.1 - 1.2e-49 169.4 0.0 2.1e-49 168.6 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Tetraspanin PF00335.20 CDJ89728.1 - 2.9e-09 37.0 8.2 5.8e-09 36.0 8.2 1.5 1 0 0 1 1 1 1 Tetraspanin family CitMHS PF03600.16 CDJ89728.1 - 5.7e-05 22.5 0.6 6.9e-05 22.2 0.6 1.1 1 0 0 1 1 1 1 Citrate transporter GWT1 PF06423.12 CDJ89728.1 - 0.27 11.4 0.1 0.27 11.4 0.1 2.4 2 0 0 2 2 2 0 GWT1 DAN PF03045.15 CDJ89730.1 - 1.6e-10 41.0 5.1 2e-10 40.7 5.1 1.1 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.22 CDJ89730.1 - 1.3e-06 28.6 8.3 1.6e-06 28.4 8.3 1.1 1 0 0 1 1 1 1 Cystine-knot domain Collagen PF01391.18 CDJ89732.1 - 5.8e-27 93.2 96.1 2.7e-09 36.6 35.6 4.1 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) DUF1679 PF07914.11 CDJ89733.1 - 1e-43 149.8 0.0 1.3e-43 149.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.23 CDJ89733.1 - 5.8e-13 49.3 0.1 2.7e-12 47.1 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CDJ89733.1 - 2e-11 43.8 0.0 3e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 CDJ89733.1 - 0.0069 16.0 0.3 0.018 14.6 0.3 1.8 1 1 0 1 1 1 1 RIO1 family Sec2p PF06428.11 CDJ89734.1 - 1.7e-05 24.7 2.1 1.7e-05 24.7 2.1 2.1 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p TBK1_CCD1 PF18394.1 CDJ89734.1 - 0.0069 16.0 1.4 0.011 15.3 1.4 1.2 1 0 0 1 1 1 1 TANK-binding kinase 1 coiled-coil domain 1 CorA PF01544.18 CDJ89734.1 - 0.04 13.2 1.1 0.067 12.5 1.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Lipoprotein_20 PF13942.6 CDJ89734.1 - 0.058 13.3 3.2 0.1 12.5 3.2 1.3 1 0 0 1 1 1 0 YfhG lipoprotein Fez1 PF06818.15 CDJ89734.1 - 0.09 13.2 8.2 0.18 12.3 8.2 1.4 1 0 0 1 1 1 0 Fez1 7TMR-HDED PF07697.11 CDJ89734.1 - 2.6 8.1 10.7 2.5 8.2 0.5 2.1 1 1 1 2 2 2 0 7TM-HD extracellular Integrase_H2C2 PF17921.1 CDJ89735.1 - 1.4e-11 44.3 0.7 2.8e-11 43.3 0.7 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Kazal_1 PF00050.21 CDJ89735.1 - 0.015 15.3 0.1 0.029 14.4 0.1 1.4 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain U1snRNP70_N PF12220.8 CDJ89736.1 - 4.8e-24 84.8 1.2 4.8e-24 84.8 1.2 1.7 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 CDJ89736.1 - 2.4e-12 46.5 0.0 4.2e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) dNK PF01712.19 CDJ89737.1 - 1.4e-14 54.4 0.0 1.8e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Deoxynucleoside kinase Zeta_toxin PF06414.12 CDJ89737.1 - 0.00038 19.8 0.0 0.00051 19.4 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin TsaE PF02367.17 CDJ89737.1 - 0.0011 18.9 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 CDJ89737.1 - 0.0035 17.9 0.0 0.0044 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ89737.1 - 0.03 14.7 0.0 0.044 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CDJ89737.1 - 0.032 14.5 0.0 0.044 14.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.6 CDJ89737.1 - 0.033 14.3 0.0 0.039 14.1 0.0 1.1 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA_33 PF13671.6 CDJ89737.1 - 0.033 14.3 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain fragilysinNterm PF16376.5 CDJ89737.1 - 0.057 13.2 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain of fragilysin Ploopntkinase3 PF18751.1 CDJ89737.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 CDJ89737.1 - 0.14 12.4 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CDJ89737.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 CDJ89737.1 - 0.15 12.5 0.0 0.23 11.9 0.0 1.4 1 1 0 1 1 1 0 RNA helicase Pkinase_Tyr PF07714.17 CDJ89740.1 - 7.7e-17 61.4 0.0 1.6e-16 60.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ89740.1 - 1.1e-12 47.9 0.0 1.6e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 CDJ89741.1 - 8.3e-15 55.2 0.0 1.3e-14 54.5 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ89741.1 - 3e-14 53.2 0.1 4.9e-14 52.5 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CDJ89741.1 - 4.5e-14 52.2 0.0 1.1e-09 38.3 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 CDJ89741.1 - 1.2e-12 46.8 0.0 3.1e-08 33.2 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CDJ89741.1 - 4.4e-11 42.8 0.2 8.9e-06 25.9 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) GCP_N_terminal PF17681.1 CDJ89742.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.0 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal FH2 PF02181.23 CDJ89743.1 - 2.6e-94 316.4 4.0 2.6e-94 316.4 4.0 2.6 2 1 1 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.13 CDJ89743.1 - 3.4e-23 82.2 9.2 3.4e-23 82.2 9.2 2.7 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 CDJ89743.1 - 7e-20 71.5 9.7 2.5e-19 69.7 9.7 2.0 1 0 0 1 1 1 1 Diaphanous FH3 Domain DUF1366 PF07104.11 CDJ89743.1 - 3.1 7.5 6.8 3.1 7.5 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1366) DUF3584 PF12128.8 CDJ89743.1 - 5.8 4.3 22.5 0.038 11.5 13.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Y_phosphatase PF00102.27 CDJ89744.1 - 7.2e-75 251.6 4.9 6.5e-71 238.6 0.2 2.6 3 0 0 3 3 3 2 Protein-tyrosine phosphatase fn3 PF00041.21 CDJ89744.1 - 7.3e-36 122.4 0.3 1.5e-13 50.9 0.5 4.5 4 0 0 4 4 4 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CDJ89744.1 - 7.6e-10 39.2 1.8 0.00073 20.1 0.4 3.6 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain DSPc PF00782.20 CDJ89744.1 - 0.00066 19.5 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PhoD_N PF16655.5 CDJ89744.1 - 0.0054 17.2 0.1 0.21 12.2 0.1 2.6 2 0 0 2 2 2 1 PhoD-like phosphatase, N-terminal domain I-set PF07679.16 CDJ89744.1 - 0.011 15.8 0.0 1.7 8.8 0.0 3.3 3 0 0 3 3 3 0 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ89744.1 - 0.014 16.0 0.0 3.1 8.5 0.0 3.2 2 0 0 2 2 2 0 Immunoglobulin domain Ig_6 PF18452.1 CDJ89744.1 - 0.049 13.2 0.0 0.55 9.8 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain Aminotran_3 PF00202.21 CDJ89745.1 - 1.4e-101 340.1 0.0 1.7e-101 339.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III NfI_DNAbd_pre-N PF10524.9 CDJ89746.1 - 1.1e-22 79.6 1.4 1.8e-22 78.9 1.4 1.3 1 0 0 1 1 1 1 Nuclear factor I protein pre-N-terminus MH1 PF03165.16 CDJ89746.1 - 1.3e-12 47.9 0.2 3.6e-12 46.4 0.1 1.8 2 0 0 2 2 2 1 MH1 domain CH PF00307.31 CDJ89747.1 - 1.9e-19 69.9 0.0 2.4e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 CDJ89747.1 - 7.1e-14 51.1 0.2 1.6e-13 50.0 0.1 1.7 2 0 0 2 2 2 1 Calponin family repeat DrsE_2 PF13686.6 CDJ89747.1 - 0.052 13.5 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family HTH_48 PF17906.1 CDJ89748.1 - 4.1e-18 65.2 1.5 7.3e-18 64.4 1.5 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_Tnp_IS630 PF01710.16 CDJ89748.1 - 6.7e-06 26.1 0.1 1.1e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 CDJ89748.1 - 7.3e-06 25.6 0.1 0.029 14.2 0.0 2.5 2 0 0 2 2 2 2 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 CDJ89748.1 - 1.1e-05 25.6 2.2 2.7e-05 24.3 1.3 2.0 2 0 0 2 2 2 1 Transposase HTH_38 PF13936.6 CDJ89748.1 - 1.3e-05 24.9 0.6 7e-05 22.5 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_50 PF18024.1 CDJ89748.1 - 0.00027 20.5 0.0 0.00057 19.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 CDJ89748.1 - 0.00034 20.7 0.0 1.1 9.4 0.0 2.8 3 0 0 3 3 2 2 Helix-turn-helix domain HTH_32 PF13565.6 CDJ89748.1 - 0.0012 19.5 0.0 0.0012 19.5 0.0 2.1 2 1 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_1 PF01527.20 CDJ89748.1 - 0.0014 18.9 0.2 0.51 10.7 0.0 2.3 1 1 1 2 2 2 1 Transposase HTH_11 PF08279.12 CDJ89748.1 - 0.0045 16.9 0.0 0.0082 16.1 0.0 1.4 1 0 0 1 1 1 1 HTH domain HTH_29 PF13551.6 CDJ89748.1 - 0.0057 16.6 0.0 0.43 10.6 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn helix TnsD PF15978.5 CDJ89748.1 - 0.0088 15.1 0.9 0.01 14.9 0.9 1.2 1 0 0 1 1 1 1 Tn7-like transposition protein D HTH_40 PF14493.6 CDJ89748.1 - 0.019 15.4 0.2 0.034 14.6 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain IF2_N PF04760.15 CDJ89748.1 - 0.02 14.7 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Terminase_5 PF06056.12 CDJ89748.1 - 0.033 14.1 0.0 5.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) Transposase_1 PF01359.18 CDJ89748.1 - 0.035 13.9 0.5 0.095 12.5 0.5 1.8 1 0 0 1 1 1 0 Transposase (partial DDE domain) HTH_Tnp_ISL3 PF13542.6 CDJ89748.1 - 0.046 13.1 0.1 0.37 10.3 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_10 PF04967.12 CDJ89748.1 - 0.058 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain HTH_36 PF13730.6 CDJ89748.1 - 0.067 13.2 0.0 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_5 PF01022.20 CDJ89748.1 - 0.077 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_30 PF13556.6 CDJ89748.1 - 0.078 12.8 0.2 0.18 11.6 0.2 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_6 PF01418.17 CDJ89748.1 - 0.099 12.6 0.0 0.33 11.0 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family GerE PF00196.19 CDJ89748.1 - 0.13 11.8 0.3 0.3 10.7 0.3 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Nipped-B_C PF12830.7 CDJ89749.1 - 1.8e-53 181.4 0.0 1.8e-53 181.4 0.0 5.1 5 0 0 5 5 5 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 CDJ89749.1 - 1.9e-10 40.8 1.7 4e-09 36.6 0.2 3.5 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 CDJ89749.1 - 0.002 18.2 0.2 21 5.7 0.0 5.7 6 0 0 6 6 6 1 HEAT repeat Peptidase_S28 PF05577.12 CDJ89750.1 - 1.6e-130 435.8 5.1 1.8e-130 435.6 5.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 CDJ89750.1 - 5.2e-07 28.7 1.2 9e-06 24.6 0.8 2.2 2 0 0 2 2 2 2 PS-10 peptidase S37 Peptidase_S28 PF05577.12 CDJ89751.1 - 1.7e-126 422.6 3.9 1.9e-126 422.4 3.9 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 CDJ89751.1 - 0.0047 15.7 0.4 0.067 11.9 0.1 2.1 2 0 0 2 2 2 1 PS-10 peptidase S37 Hydrolase_4 PF12146.8 CDJ89751.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Runt PF00853.19 CDJ89751.1 - 0.13 11.9 0.6 0.27 10.8 0.2 1.6 2 0 0 2 2 2 0 Runt domain C2-C2_1 PF11618.8 CDJ89753.1 - 1.7e-24 86.5 3.1 4.1e-24 85.3 0.3 3.0 4 0 0 4 4 4 1 First C2 domain of RPGR-interacting protein 1 Spc42p PF11544.8 CDJ89753.1 - 0.0002 21.3 0.7 0.0002 21.3 0.7 4.2 5 1 1 6 6 6 1 Spindle pole body component Spc42p GYD PF08734.11 CDJ89753.1 - 0.26 11.3 1.2 0.55 10.2 0.0 2.2 2 0 0 2 2 2 0 GYD domain Ribosomal_L7Ae PF01248.26 CDJ89756.1 - 1.7e-25 88.6 0.1 2e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.6 CDJ89756.1 - 0.02 15.0 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase RRM_1 PF00076.22 CDJ89757.1 - 4.5e-33 112.9 0.0 1.5e-16 60.0 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 CDJ89757.1 - 0.00019 21.4 0.1 0.45 10.6 0.0 2.9 2 2 0 2 2 2 2 RNA binding domain RRM_7 PF16367.5 CDJ89757.1 - 0.0048 17.0 0.0 4.6 7.4 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif PHM7_cyt PF14703.6 CDJ89757.1 - 0.025 14.8 0.2 8.4 6.6 0.0 3.3 1 1 2 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 CDJ89757.1 - 0.038 14.0 0.1 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Collagen PF01391.18 CDJ89758.1 - 3.9e-27 93.8 105.4 6.5e-11 41.8 40.5 3.4 3 0 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ89758.1 - 4.1e-17 62.0 0.1 5.5e-17 61.6 0.1 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ89759.1 - 1.4e-21 76.0 119.5 0.00018 21.2 11.8 4.1 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ89759.1 - 3.4e-06 27.0 0.8 4.3e-06 26.7 0.8 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain FeoB_associated PF12669.7 CDJ89759.1 - 4.8 7.7 7.7 4.1 7.9 2.5 2.2 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Collagen PF01391.18 CDJ89760.1 - 1.2e-23 82.6 119.5 1.3e-09 37.6 40.5 4.1 2 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ89760.1 - 0.00018 21.5 0.2 0.00023 21.1 0.2 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain FeoB_associated PF12669.7 CDJ89760.1 - 2.2 8.8 8.7 1.2 9.6 2.2 2.3 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Collagen PF01391.18 CDJ89761.1 - 4.8e-23 80.7 117.4 1.6e-09 37.4 41.2 4.0 2 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ89761.1 - 1e-19 70.3 0.6 1.3e-19 70.0 0.6 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Oleosin PF01277.17 CDJ89761.1 - 0.19 11.5 0.1 0.25 11.1 0.1 1.1 1 0 0 1 1 1 0 Oleosin Collagen PF01391.18 CDJ89762.1 - 2.6e-25 88.0 111.3 3.8e-05 23.4 14.9 4.0 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ89762.1 - 0.00011 22.2 0.3 0.00014 21.9 0.3 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain FeoB_associated PF12669.7 CDJ89762.1 - 3.4 8.1 7.7 4 7.9 2.5 2.3 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein MFS_1 PF07690.16 CDJ89763.1 - 5.2e-17 61.8 10.5 8.5e-17 61.1 10.5 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Methyltr_RsmB-F PF01189.17 CDJ89764.1 - 1e-65 221.1 0.0 1.8e-65 220.3 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 CDJ89764.1 - 6.7e-09 36.1 0.0 3.4e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 CDJ89764.1 - 0.00051 20.2 0.1 0.0011 19.1 0.1 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase zf-H2C2_2 PF13465.6 CDJ89765.1 - 6.3e-25 86.4 44.0 6.5e-07 29.5 0.3 8.3 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2 PF00096.26 CDJ89765.1 - 6.9e-23 79.8 51.7 1.3e-05 25.4 0.3 7.6 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ89765.1 - 7.4e-20 69.9 52.5 0.00079 20.1 0.5 7.5 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ89765.1 - 1.2e-13 50.9 18.4 9e-05 22.7 0.2 7.4 7 0 0 7 7 7 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CDJ89765.1 - 1.3e-07 31.4 40.3 0.0019 18.2 0.2 7.4 7 0 0 7 7 7 4 C2H2-type zinc finger zf-met PF12874.7 CDJ89765.1 - 0.00064 20.0 37.4 0.47 10.9 0.0 7.5 7 1 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 CDJ89765.1 - 0.001 18.8 0.4 0.001 18.8 0.4 6.1 7 1 0 7 7 5 2 zinc-finger C2H2-type zf-Di19 PF05605.12 CDJ89765.1 - 0.0037 17.5 28.3 0.0075 16.5 0.5 4.3 4 0 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding PyrI_C PF02748.15 CDJ89765.1 - 0.21 11.5 13.9 0.5 10.3 0.1 4.9 6 0 0 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain GAGA PF09237.11 CDJ89765.1 - 0.37 10.6 5.2 0.15 11.9 0.4 2.6 2 1 1 3 3 3 0 GAGA factor zf-Sec23_Sec24 PF04810.15 CDJ89765.1 - 0.7 10.0 24.8 5.6 7.1 2.6 5.6 5 1 1 6 6 6 0 Sec23/Sec24 zinc finger zf-C2H2_2 PF12756.7 CDJ89765.1 - 5 7.5 32.4 72 3.8 6.3 6.8 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 CDJ89765.1 - 5.6 7.8 23.1 24 5.8 5.7 4.2 1 1 2 3 3 3 0 zinc-ribbon family VGCC_alpha2 PF08473.11 CDJ89767.1 - 0.026 13.3 0.0 0.034 12.9 0.0 1.1 1 0 0 1 1 1 0 Neuronal voltage-dependent calcium channel alpha 2acd PepSY_TM_like_2 PF16357.5 CDJ89767.1 - 0.23 11.4 3.5 4 7.4 0.0 2.4 2 1 1 3 3 3 0 Putative PepSY_TM-like Prenyltrans PF00432.21 CDJ89768.1 - 4.6e-26 90.3 6.5 5.8e-09 35.5 0.0 6.2 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat WASH_WAHD PF11945.8 CDJ89768.1 - 1.4e-23 83.9 0.0 2.2e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 WAHD domain of WASH complex RCC1_2 PF13540.6 CDJ89768.1 - 3e-07 30.1 2.6 7e-05 22.5 0.1 2.9 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 CDJ89768.1 - 0.00048 20.7 0.1 0.0076 16.9 0.0 2.5 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat CAP_N PF01213.19 CDJ89768.1 - 0.0025 17.4 9.6 0.0054 16.3 9.6 1.6 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal WH2 PF02205.20 CDJ89768.1 - 0.0043 16.8 0.3 0.0043 16.8 0.3 2.6 2 0 0 2 2 2 1 WH2 motif Mito_fiss_reg PF05308.11 CDJ89768.1 - 0.42 10.7 8.2 4 7.5 8.9 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator PIG-P PF08510.12 CDJ89769.1 - 4e-13 49.3 1.7 9.5e-13 48.1 1.7 1.6 1 0 0 1 1 1 1 PIG-P MMR_HSR1 PF01926.23 CDJ89769.1 - 1.3e-08 34.9 0.0 1e-07 32.0 0.0 2.5 3 1 0 3 3 3 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CDJ89769.1 - 0.0028 17.7 0.0 0.011 15.8 0.0 2.1 2 1 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 CDJ89769.1 - 0.0035 16.9 0.0 0.1 12.1 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CDJ89769.1 - 0.0052 16.3 0.0 0.15 11.6 0.0 2.8 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CDJ89769.1 - 0.019 14.9 0.0 0.065 13.1 0.0 1.9 1 1 0 1 1 1 0 RsgA GTPase PXA PF02194.15 CDJ89770.1 - 6.1e-27 94.8 0.4 2.1e-26 93.0 0.4 2.0 1 0 0 1 1 1 1 PXA domain PX PF00787.24 CDJ89770.1 - 8.8e-14 51.5 0.8 8.8e-14 51.5 0.8 2.0 2 0 0 2 2 2 1 PX domain RGS PF00615.19 CDJ89770.1 - 3.1e-08 33.9 0.9 3.1e-08 33.9 0.9 2.9 3 0 0 3 3 3 1 Regulator of G protein signaling domain Nexin_C PF08628.12 CDJ89770.1 - 0.019 15.6 0.1 0.1 13.2 0.0 2.4 2 0 0 2 2 2 0 Sorting nexin C terminal Transglut_i_TM PF14400.6 CDJ89770.1 - 0.068 13.2 0.4 0.38 10.8 0.0 2.3 3 0 0 3 3 3 0 Inactive transglutaminase fused to 7 transmembrane helices Glutaminase PF04960.15 CDJ89773.1 - 3.3e-116 387.5 0.0 4.9e-116 386.9 0.0 1.3 1 0 0 1 1 1 1 Glutaminase EF-hand_14 PF17959.1 CDJ89773.1 - 2.3e-26 91.9 0.4 5.7e-26 90.7 0.4 1.7 1 0 0 1 1 1 1 EF-hand domain Ank_4 PF13637.6 CDJ89773.1 - 2.2e-10 40.9 0.0 9.8e-06 26.0 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ89773.1 - 5.1e-09 36.6 0.0 1.7e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ89773.1 - 6.2e-08 32.8 0.1 1.9e-07 31.2 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ89773.1 - 6.7e-05 23.0 0.0 0.00071 19.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 CDJ89773.1 - 0.00025 21.4 0.0 0.00073 19.9 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat RVT_1 PF00078.27 CDJ89774.1 - 7.3e-11 42.0 0.0 7.5e-11 42.0 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sigma70_r4_2 PF08281.12 CDJ89774.1 - 0.07 12.8 0.2 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 Ammonium_transp PF00909.21 CDJ89775.1 - 1.2e-119 399.6 21.8 1.5e-119 399.3 21.8 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family DUF2457 PF10446.9 CDJ89775.1 - 0.99 8.5 6.7 1.9 7.6 6.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PLAT PF01477.23 CDJ89776.1 - 0.05 14.2 0.2 0.054 14.1 0.2 1.1 1 0 0 1 1 1 0 PLAT/LH2 domain TFIIE_beta PF02186.15 CDJ89776.1 - 0.061 13.6 0.2 0.079 13.3 0.2 1.2 1 0 0 1 1 1 0 TFIIE beta subunit core domain Voltage_CLC PF00654.20 CDJ89777.1 - 2.5e-73 247.4 30.3 2.5e-73 247.4 30.3 1.8 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 CDJ89777.1 - 1.7e-06 28.3 0.2 0.054 14.0 0.1 2.6 2 0 0 2 2 2 2 CBS domain ICMT PF04140.14 CDJ89777.1 - 3 8.3 6.0 12 6.4 0.0 2.9 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family CENP-B_dimeris PF09026.10 CDJ89777.1 - 7.8 7.0 9.0 6 7.3 6.6 2.2 2 1 0 2 2 2 0 Centromere protein B dimerisation domain DNase_II PF03265.15 CDJ89778.1 - 3.1e-13 49.7 0.0 3.5e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II Spore_GerQ PF09671.10 CDJ89778.1 - 0.065 13.2 0.0 0.077 13.0 0.0 1.1 1 0 0 1 1 1 0 Spore coat protein (Spore_GerQ) BLM10_mid PF16507.5 CDJ89780.1 - 4e-07 29.1 0.2 4.4e-07 28.9 0.2 1.0 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region Methuselah_N PF06652.12 CDJ89780.1 - 0.15 11.9 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Methuselah N-terminus Glycos_transf_2 PF00535.26 CDJ89781.1 - 2.6e-33 115.2 0.0 4.3e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CDJ89781.1 - 2.8e-16 59.9 0.0 5.4e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 CDJ89781.1 - 8.9e-08 32.3 0.0 1.3e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 CDJ89781.1 - 4.8e-06 26.1 0.1 1.1e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CDJ89781.1 - 0.00026 20.6 0.0 0.19 11.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 SUI1 PF01253.22 CDJ89782.1 - 1.5e-17 63.9 1.0 4.5e-17 62.3 0.1 1.9 1 1 1 2 2 2 1 Translation initiation factor SUI1 Ricin_B_lectin PF00652.22 CDJ89783.1 - 8.1e-20 71.4 0.5 3.8e-19 69.2 0.7 1.9 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Glycos_transf_2 PF00535.26 CDJ89783.1 - 1e-19 71.0 0.2 2.2e-19 69.9 0.1 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 RicinB_lectin_2 PF14200.6 CDJ89783.1 - 0.056 14.2 0.1 0.13 13.0 0.1 1.6 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like Cation_ATPase_C PF00689.21 CDJ89784.1 - 1.8e-36 125.6 10.1 3e-35 121.6 10.1 2.2 1 1 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CDJ89784.1 - 1.5e-15 58.1 0.0 4.8e-15 56.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CDJ89784.1 - 7.2e-06 26.5 0.0 7.4e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDJ89784.1 - 9e-06 25.6 1.2 9e-06 25.6 1.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2205 PF10224.9 CDJ89785.1 - 0.0083 16.1 1.2 0.037 14.0 1.2 2.1 1 0 0 1 1 1 1 Short coiled-coil protein AKNA PF12443.8 CDJ89785.1 - 0.036 14.7 6.2 29 5.4 0.1 3.4 3 0 0 3 3 3 0 AT-hook-containing transcription factor FlaC_arch PF05377.11 CDJ89785.1 - 0.22 11.9 2.8 0.39 11.1 0.5 2.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Allexi_40kDa PF05549.11 CDJ89785.1 - 0.25 10.8 4.7 0.71 9.3 1.9 2.6 2 1 1 3 3 3 0 Allexivirus 40kDa protein DUF16 PF01519.16 CDJ89785.1 - 0.44 11.1 7.8 1.1 9.7 2.0 3.1 3 0 0 3 3 3 0 Protein of unknown function DUF16 DUF1623 PF07785.11 CDJ89785.1 - 0.59 10.3 8.3 17 5.7 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1623) DUF1978 PF09321.10 CDJ89785.1 - 0.68 9.2 7.4 43 3.3 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1978) DUF3782 PF12644.7 CDJ89785.1 - 3.6 7.8 6.2 62 3.8 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3782) DUF2203 PF09969.9 CDJ89785.1 - 5.1 7.8 6.3 5.4 7.8 0.5 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) XhlA PF10779.9 CDJ89785.1 - 5.9 7.2 5.9 6.6 7.0 0.2 3.3 3 0 0 3 3 3 0 Haemolysin XhlA CLZ PF16526.5 CDJ89785.1 - 7.3 7.0 12.8 11 6.4 0.4 3.5 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3459 PF11941.8 CDJ89786.1 - 0.94 9.8 3.5 5.2 7.5 2.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3459) Amidinotransf PF02274.17 CDJ89787.1 - 6.1e-27 94.6 0.0 1.8e-25 89.7 0.0 2.0 1 1 0 1 1 1 1 Amidinotransferase Oxidored_molyb PF00174.19 CDJ89788.1 - 2.4e-61 206.3 0.0 3.5e-61 205.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 CDJ89788.1 - 8.9e-42 142.4 1.0 1.5e-41 141.6 0.3 1.7 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 CDJ89788.1 - 6e-14 52.0 0.1 1.2e-13 51.0 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PUA PF01472.20 CDJ89789.1 - 3e-19 68.7 2.4 3e-19 68.7 1.1 1.7 2 0 0 2 2 2 1 PUA domain TruB_C_2 PF16198.5 CDJ89789.1 - 1e-18 67.2 1.6 1.8e-18 66.4 1.6 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain UPF0113 PF03657.13 CDJ89789.1 - 0.00052 20.2 0.1 0.0015 18.8 0.0 1.9 2 0 0 2 2 2 1 UPF0113 PUA domain LRIF1 PF15741.5 CDJ89790.1 - 0.066 11.8 0.1 0.066 11.7 0.1 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Tetraspanin PF00335.20 CDJ89791.1 - 5e-07 29.7 4.7 7.8e-07 29.0 4.7 1.3 1 0 0 1 1 1 1 Tetraspanin family DHHC PF01529.20 CDJ89792.1 - 2.7e-38 131.1 16.8 2.7e-38 131.1 16.8 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Tmemb_9 PF05434.11 CDJ89792.1 - 0.17 11.8 1.7 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 TMEM9 EMG1 PF03587.14 CDJ89793.1 - 6e-71 238.1 0.0 7.2e-71 237.9 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Zw10 PF06248.13 CDJ89793.1 - 0.17 10.4 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Rad9 PF04139.13 CDJ89794.1 - 4.4e-45 154.1 9.8 5.2e-45 153.9 9.8 1.0 1 0 0 1 1 1 1 Rad9 Ground-like PF04155.18 CDJ89795.1 - 1.4e-17 64.1 0.3 1.8e-17 63.7 0.3 1.2 1 0 0 1 1 1 1 Ground-like domain CLU_N PF15044.6 CDJ89795.1 - 0.085 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial function, CLU-N-term PRA1 PF03208.19 CDJ89796.1 - 5.2e-28 97.5 6.2 6.1e-28 97.3 6.2 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF3784 PF12650.7 CDJ89796.1 - 0.27 11.5 4.1 1 9.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) MNHE PF01899.16 CDJ89796.1 - 0.66 9.7 4.2 0.92 9.3 4.2 1.2 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit DUF4229 PF14012.6 CDJ89796.1 - 5.8 7.1 10.1 0.49 10.5 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Y_phosphatase PF00102.27 CDJ89797.1 - 1.7e-36 126.0 0.0 2.4e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CDJ89797.1 - 0.00096 19.2 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CDJ89797.1 - 0.002 18.0 0.0 0.004 17.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CDJ89797.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate EMP24_GP25L PF01105.24 CDJ89798.1 - 1.3e-47 162.2 0.2 1.6e-47 161.8 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD FCD PF07729.12 CDJ89798.1 - 0.015 15.7 0.1 0.023 15.1 0.1 1.2 1 0 0 1 1 1 0 FCD domain Innexin PF00876.18 CDJ89798.1 - 0.02 14.2 0.2 0.027 13.8 0.2 1.3 1 0 0 1 1 1 0 Innexin SdrD_B PF17210.3 CDJ89798.1 - 0.078 13.2 0.4 0.18 12.0 0.4 1.7 1 1 0 1 1 1 0 SdrD B-like domain LBP_BPI_CETP_C PF02886.17 CDJ89800.1 - 2.6e-22 79.4 0.2 3.9e-22 78.9 0.2 1.2 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 CDJ89800.1 - 2.4e-15 56.5 0.0 4.2e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain zf-RING_9 PF13901.6 CDJ89802.1 - 8.6e-60 202.2 32.3 8.3e-59 199.0 16.2 2.5 2 1 0 2 2 2 2 Putative zinc-RING and/or ribbon C1_1 PF00130.22 CDJ89802.1 - 3.7e-06 26.7 6.3 3.7e-06 26.7 6.3 4.2 3 2 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 CDJ89802.1 - 0.024 14.6 9.8 0.024 14.6 9.8 4.5 4 2 0 4 4 4 0 Prokaryotic RING finger family 1 Comm PF15957.5 CDJ89803.1 - 0.023 15.0 0.1 0.023 15.0 0.1 1.1 1 0 0 1 1 1 0 Commissureless HMG_box PF00505.19 CDJ89804.1 - 9.1e-36 122.1 13.3 6.7e-22 77.7 3.0 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ89804.1 - 6.9e-33 113.1 14.5 1.4e-17 64.1 3.1 2.2 2 0 0 2 2 2 2 HMG-box domain DUF4776 PF16003.5 CDJ89804.1 - 0.014 14.5 6.0 0.02 13.9 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) HMG_box_5 PF14887.6 CDJ89804.1 - 0.026 14.5 1.4 0.026 14.5 1.4 2.5 2 1 0 2 2 2 0 HMG (high mobility group) box 5 Ccdc124 PF06244.12 CDJ89804.1 - 0.17 12.5 8.5 0.05 14.2 5.6 1.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 124 /Oxs1 FTCD_C PF04961.12 CDJ89804.1 - 0.65 9.7 5.9 0.96 9.2 2.7 2.1 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase COX4 PF02936.14 CDJ89804.1 - 0.69 9.9 6.3 0.34 10.9 1.0 2.7 2 1 0 2 2 2 0 Cytochrome c oxidase subunit IV GPCR_chapero_1 PF11904.8 CDJ89805.1 - 1.6e-84 284.0 0.1 3e-84 283.1 0.1 1.4 1 0 0 1 1 1 1 GPCR-chaperone Lipase_3 PF01764.25 CDJ89805.1 - 1e-32 112.9 0.0 2.4e-32 111.8 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Ank PF00023.30 CDJ89805.1 - 1.3e-06 28.6 0.0 4.5e-06 26.9 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 CDJ89805.1 - 3.9e-06 27.3 0.0 2.8e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ89805.1 - 0.00027 21.4 0.0 0.12 13.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ89805.1 - 0.0022 18.3 0.0 0.13 12.8 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Abhydrolase_6 PF12697.7 CDJ89805.1 - 0.02 15.5 0.0 0.042 14.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ank_5 PF13857.6 CDJ89805.1 - 0.048 14.0 0.0 0.42 11.0 0.0 2.4 1 1 1 2 2 2 0 Ankyrin repeats (many copies) DUF2048 PF09752.9 CDJ89805.1 - 0.11 11.6 0.0 0.31 10.1 0.0 1.7 2 0 0 2 2 2 0 Abhydrolase domain containing 18 Lipase_3 PF01764.25 CDJ89806.1 - 8.2e-36 123.0 0.0 1.1e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CDJ89806.1 - 0.0025 18.4 0.0 0.0045 17.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 CDJ89806.1 - 0.02 14.5 0.1 0.099 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF2048 PF09752.9 CDJ89806.1 - 0.022 13.9 0.0 0.043 12.9 0.0 1.5 2 0 0 2 2 2 0 Abhydrolase domain containing 18 DUF676 PF05057.14 CDJ89806.1 - 0.051 13.1 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 CDJ89806.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 CDJ89806.1 - 0.057 13.1 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 CDJ89806.1 - 0.057 13.2 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDJ89806.1 - 0.08 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Pkinase PF00069.25 CDJ89807.1 - 1.4e-67 227.8 0.0 2e-67 227.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ89807.1 - 2e-34 119.0 0.0 3e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ89807.1 - 4.7e-07 29.4 0.0 1.3e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CDJ89807.1 - 7.9e-06 25.4 0.2 1.3e-05 24.6 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDJ89807.1 - 0.0021 17.0 0.2 0.0045 16.0 0.2 1.5 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CDJ89807.1 - 0.036 14.0 0.1 0.27 11.1 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ89807.1 - 0.046 12.5 0.6 0.09 11.5 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase FTA2 PF13095.6 CDJ89807.1 - 0.15 11.7 0.6 13 5.3 0.0 2.7 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RAP1 PF07218.11 CDJ89808.1 - 3.1 6.0 14.3 4.2 5.5 14.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CDC45 PF02724.14 CDJ89808.1 - 5.9 5.0 12.0 10 4.2 12.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Menin PF05053.13 CDJ89808.1 - 8.5 4.6 9.5 12 4.1 9.5 1.2 1 0 0 1 1 1 0 Menin Galactosyl_T PF01762.21 CDJ89809.1 - 2.8e-36 125.2 0.1 3.7e-36 124.8 0.1 1.1 1 0 0 1 1 1 1 Galactosyltransferase Focal_AT PF03623.13 CDJ89811.1 - 0.021 14.8 0.8 0.12 12.4 0.2 1.9 1 1 1 2 2 2 0 Focal adhesion targeting region Sec20 PF03908.13 CDJ89812.1 - 0.00062 19.6 0.2 0.00074 19.4 0.2 1.2 1 0 0 1 1 1 1 Sec20 Use1 PF09753.9 CDJ89812.1 - 0.0059 16.4 0.0 0.0073 16.1 0.0 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 APG17 PF04108.12 CDJ89812.1 - 0.023 13.8 0.0 0.027 13.6 0.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg17 Tropomyosin PF00261.20 CDJ89812.1 - 0.15 11.4 0.1 0.5 9.7 0.1 1.6 1 1 0 1 1 1 0 Tropomyosin SNARE PF05739.19 CDJ89812.1 - 0.17 11.9 0.3 0.39 10.7 0.3 1.7 1 1 0 1 1 1 0 SNARE domain SelK_SelG PF10961.8 CDJ89813.1 - 4.2e-11 43.3 17.7 2.7e-10 40.7 17.7 1.8 1 1 0 1 1 1 1 Selenoprotein SelK_SelG UCH PF00443.29 CDJ89817.1 - 1.1e-67 228.2 0.1 1.7e-67 227.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ89817.1 - 9.7e-14 51.7 0.1 4.7e-08 33.0 0.0 3.4 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zf-MYND PF01753.18 CDJ89817.1 - 3.5e-07 30.2 12.2 3.5e-07 30.2 12.2 2.7 3 0 0 3 3 3 1 MYND finger USP7_C2 PF14533.6 CDJ89817.1 - 0.0001 22.1 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal DUF1258 PF06869.12 CDJ89817.1 - 0.25 10.8 1.3 0.66 9.4 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1258) zf-C6H2 PF15801.5 CDJ89817.1 - 0.45 10.9 8.9 11 6.4 0.1 2.6 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zinc-ribbons_6 PF07191.12 CDJ89817.1 - 9.2 6.3 11.6 2.7 8.1 4.5 2.9 3 0 0 3 3 3 0 zinc-ribbons PfkB PF00294.24 CDJ89818.1 - 1.3e-16 60.8 0.1 1.6e-16 60.5 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase T-box PF00907.22 CDJ89820.1 - 3.1e-77 259.0 0.1 3.9e-77 258.7 0.1 1.1 1 0 0 1 1 1 1 T-box Copine PF07002.16 CDJ89821.1 - 1.5e-42 145.5 0.0 2.9e-42 144.6 0.0 1.4 1 0 0 1 1 1 1 Copine VWA PF00092.28 CDJ89821.1 - 0.00015 22.1 0.0 0.00028 21.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 CDJ89821.1 - 0.055 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus DUF4065 PF13274.6 CDJ89821.1 - 0.062 14.2 0.0 0.13 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) CBM_14 PF01607.24 CDJ89823.1 - 6e-05 23.1 1.1 6e-05 23.1 1.1 5.6 6 0 0 6 6 6 2 Chitin binding Peritrophin-A domain DUF5401 PF17380.2 CDJ89823.1 - 4.1 5.3 5.7 1.2 7.1 2.6 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5401) fn3 PF00041.21 CDJ89824.1 - 3.7e-22 78.5 0.0 2.3e-11 43.9 0.0 2.5 2 0 0 2 2 2 2 Fibronectin type III domain 7TM_GPCR_Srd PF10317.9 CDJ89824.1 - 0.03 13.5 0.1 0.047 12.9 0.1 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd Orf78 PF06024.12 CDJ89824.1 - 0.051 13.9 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) DUF2207 PF09972.9 CDJ89824.1 - 0.092 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) BatD PF13584.6 CDJ89824.1 - 0.098 11.5 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 Oxygen tolerance DUF3149 PF11346.8 CDJ89824.1 - 0.11 12.1 0.6 0.22 11.2 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) TssO PF17561.2 CDJ89824.1 - 0.12 12.5 0.2 0.21 11.7 0.2 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssO Phage_holin_2_4 PF16082.5 CDJ89824.1 - 0.18 11.6 0.0 0.42 10.4 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like ASC PF00858.24 CDJ89826.1 - 3.8e-109 365.6 41.9 6e-108 361.6 41.9 3.5 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel Gtr1_RagA PF04670.12 CDJ89827.1 - 2.9e-63 213.3 0.9 3.8e-63 212.9 0.9 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CDJ89827.1 - 0.0015 18.0 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CDJ89827.1 - 0.014 15.8 0.0 0.024 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain SH3_1 PF00018.28 CDJ89828.1 - 2.8e-60 199.7 9.7 2.9e-15 55.6 0.0 5.4 5 0 0 5 5 5 5 SH3 domain SH3_9 PF14604.6 CDJ89828.1 - 4.5e-57 189.7 3.4 4.8e-15 55.2 0.0 5.4 5 0 0 5 5 5 5 Variant SH3 domain SH3_2 PF07653.17 CDJ89828.1 - 4.7e-53 176.7 0.7 2.7e-13 49.4 0.0 5.4 5 0 0 5 5 5 5 Variant SH3 domain EF-hand_4 PF12763.7 CDJ89828.1 - 4.3e-26 90.9 0.0 2.9e-12 46.5 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CDJ89828.1 - 7.3e-09 34.6 0.0 0.0024 17.3 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDJ89828.1 - 4.1e-06 27.2 0.0 0.095 13.2 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ89828.1 - 8.5e-06 25.3 0.0 0.11 12.5 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDJ89828.1 - 7.6e-05 22.0 0.1 0.27 10.8 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDJ89828.1 - 0.029 14.2 0.0 4.4 7.2 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair Mito_carr PF00153.27 CDJ89831.1 - 5.9e-56 186.4 4.8 3e-18 65.5 0.0 4.0 4 0 0 4 4 4 3 Mitochondrial carrier protein Utp11 PF03998.13 CDJ89831.1 - 1.2e-52 179.3 28.3 3e-52 178.0 28.3 1.7 1 0 0 1 1 1 1 Utp11 protein tRNA-synt_1 PF00133.22 CDJ89831.1 - 3.5e-36 124.6 0.0 2.1e-22 79.1 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDJ89831.1 - 4.2e-16 59.3 0.2 1.4e-15 57.5 0.2 2.0 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA E2F_TDP PF02319.20 CDJ89831.1 - 2.8e-15 56.1 0.4 2.7e-14 53.0 0.0 2.8 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain tRNA-synt_1g PF09334.11 CDJ89831.1 - 5e-15 55.1 0.0 6.9e-07 28.3 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CDJ89831.1 - 5.1e-05 22.8 0.0 0.00017 21.0 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Spermine_synth PF01564.17 CDJ89832.1 - 0.0065 15.9 0.2 0.0077 15.7 0.2 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synth PF01564.17 CDJ89833.1 - 3.4e-05 23.3 0.2 5.8e-05 22.6 0.2 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain DUF2615 PF11027.8 CDJ89833.1 - 0.014 15.6 0.1 0.044 13.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) TMEM132D_C PF15706.5 CDJ89833.1 - 0.16 11.7 0.1 0.3 10.9 0.1 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Methyltransf_4 PF02390.17 CDJ89833.1 - 0.19 11.2 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Spermine_synth PF01564.17 CDJ89834.1 - 2.1e-06 27.3 0.1 3.1e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain MTS PF05175.14 CDJ89834.1 - 0.084 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Spermine_synth PF01564.17 CDJ89836.1 - 8.9e-08 31.8 0.1 1.3e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_31 PF13847.6 CDJ89836.1 - 3.3e-07 30.2 0.0 4.7e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ89836.1 - 0.00023 21.0 0.0 0.00034 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ89836.1 - 0.00061 20.5 0.0 0.0023 18.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 CDJ89836.1 - 0.023 14.2 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 CDJ89836.1 - 0.051 13.1 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain ParB_C PF18064.1 CDJ89836.1 - 0.2 11.8 0.0 0.37 11.0 0.0 1.4 1 0 0 1 1 1 0 Centromere-binding protein ParB C-terminal Methyltransf_4 PF02390.17 CDJ89837.1 - 0.025 14.1 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 CDJ89837.1 - 0.13 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CAP PF00188.26 CDJ89838.1 - 1.6e-06 28.9 0.0 2e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Homeodomain PF00046.29 CDJ89839.1 - 2.3e-21 75.4 3.5 3.5e-21 74.8 3.5 1.3 1 0 0 1 1 1 1 Homeodomain RVT_1 PF00078.27 CDJ89840.1 - 1.1e-10 41.4 0.0 1.8e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Promethin PF16015.5 CDJ89841.1 - 0.06 13.3 3.3 0.09 12.7 3.3 1.3 1 0 0 1 1 1 0 Promethin LLGL PF08366.13 CDJ89842.1 - 1e-21 77.2 0.0 2.2e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 LLGL2 ANAPC4_WD40 PF12894.7 CDJ89842.1 - 3.1e-09 37.0 0.1 0.091 13.1 0.1 5.8 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ89842.1 - 1.3e-08 35.3 9.2 1.1 10.3 0.1 7.5 7 1 0 7 7 7 3 WD domain, G-beta repeat Lgl_C PF08596.10 CDJ89842.1 - 3e-06 26.2 0.0 0.00011 21.1 0.0 3.1 5 0 0 5 5 5 1 Lethal giant larvae(Lgl) like, C-terminal Synaptobrevin PF00957.21 CDJ89842.1 - 0.00022 21.0 1.2 0.00044 20.0 1.2 1.4 1 0 0 1 1 1 1 Synaptobrevin WD40_like PF17005.5 CDJ89842.1 - 0.0071 15.7 0.2 0.026 13.9 0.1 1.9 2 0 0 2 2 2 1 WD40-like domain P4Ha_N PF08336.11 CDJ89844.1 - 1.3e-39 135.3 1.2 2.5e-39 134.4 0.3 1.9 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 CDJ89844.1 - 1.1e-13 51.9 0.1 1.9e-13 51.1 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ANAPC3 PF12895.7 CDJ89844.1 - 0.00013 22.1 1.7 0.032 14.5 0.2 2.9 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CDJ89844.1 - 0.00026 20.9 4.2 0.00052 19.9 1.5 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ89844.1 - 0.0081 16.7 0.8 0.02 15.4 0.8 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ89844.1 - 0.0097 16.7 0.7 0.0097 16.7 0.7 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat YfiO PF13525.6 CDJ89844.1 - 0.027 14.2 1.4 0.057 13.1 0.4 2.0 2 0 0 2 2 2 0 Outer membrane lipoprotein TPR_16 PF13432.6 CDJ89844.1 - 0.029 15.0 2.1 0.029 15.0 2.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ89844.1 - 0.15 12.8 0.6 0.87 10.4 0.6 2.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Plasmod_dom_1 PF09715.10 CDJ89845.1 - 0.1 12.6 0.1 7.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) RVT_1 PF00078.27 CDJ89846.1 - 2e-24 86.3 0.0 3.1e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Methyltr_RsmF_N PF17125.5 CDJ89846.1 - 0.091 13.3 0.1 1.1 9.8 0.0 2.6 2 1 1 3 3 3 0 N-terminal domain of 16S rRNA methyltransferase RsmF MgtE PF01769.16 CDJ89848.1 - 1.2e-36 125.9 21.8 3.8e-19 69.3 7.9 3.2 3 0 0 3 3 3 2 Divalent cation transporter Cation_efflux PF01545.21 CDJ89849.1 - 7.5e-26 91.1 16.6 9e-26 90.8 16.6 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 CDJ89849.1 - 5.8e-10 39.2 1.4 1.1e-09 38.3 1.4 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Cation_efflux PF01545.21 CDJ89850.1 - 1e-27 97.2 15.0 1.3e-27 96.8 15.0 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 CDJ89850.1 - 0.0082 16.2 1.6 0.014 15.5 1.6 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF1129 PF06570.11 CDJ89850.1 - 0.13 11.7 4.7 0.39 10.2 3.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Vps52 PF04129.12 CDJ89851.1 - 2e-140 469.0 9.3 3.2e-140 468.3 9.3 1.3 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 CDJ89851.1 - 0.00031 19.3 7.9 0.00031 19.3 7.9 2.7 3 1 0 3 3 3 1 Exocyst complex component Sec3 ApoLp-III PF07464.11 CDJ89851.1 - 0.013 15.6 2.0 0.5 10.5 0.9 3.0 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Spc7 PF08317.11 CDJ89851.1 - 0.079 11.8 4.2 0.17 10.7 4.2 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein E2F_TDP PF02319.20 CDJ89851.1 - 0.085 12.9 0.3 0.81 9.8 0.2 2.8 3 1 0 3 3 3 0 E2F/DP family winged-helix DNA-binding domain Rpn3_C PF08375.11 CDJ89851.1 - 0.11 13.0 0.4 0.71 10.3 0.0 2.5 2 0 0 2 2 2 0 Proteasome regulatory subunit C-terminal nsp7 PF08716.10 CDJ89851.1 - 0.15 12.7 2.6 0.5 11.0 0.1 3.1 3 0 0 3 3 3 0 nsp7 replicase Death PF00531.22 CDJ89852.1 - 0.00028 21.0 0.0 0.00063 19.9 0.0 1.6 1 0 0 1 1 1 1 Death domain RICH PF05062.12 CDJ89852.1 - 0.019 15.3 0.2 0.042 14.2 0.2 1.5 1 0 0 1 1 1 0 RICH domain Cation_efflux PF01545.21 CDJ89853.1 - 1.7e-48 165.0 1.5 2.1e-48 164.7 1.5 1.1 1 0 0 1 1 1 1 Cation efflux family PTPS_related PF10131.9 CDJ89853.1 - 6.7 4.9 6.6 12 4.0 6.6 1.3 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein FHA PF00498.26 CDJ89854.1 - 1.5e-15 57.2 0.0 5.4e-15 55.5 0.0 2.0 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 CDJ89854.1 - 0.00019 21.7 0.0 0.0012 19.1 0.0 2.3 3 0 0 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain Pox_A_type_inc PF04508.12 CDJ89854.1 - 0.00036 20.2 0.7 0.039 13.8 0.0 3.2 2 0 0 2 2 2 1 Viral A-type inclusion protein repeat DUF1826 PF08856.11 CDJ89854.1 - 6 6.7 7.6 2.9 7.7 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1826) XhlA PF10779.9 CDJ89854.1 - 8.1 6.7 6.6 3.6 7.9 0.8 2.8 2 0 0 2 2 2 0 Haemolysin XhlA Sulfotransfer_2 PF03567.14 CDJ89856.1 - 2.5e-13 50.5 0.1 3e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family Mei4 PF13971.6 CDJ89857.1 - 0.0096 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 Meiosis-specific protein Mei4 O-antigen_lig PF13425.6 CDJ89857.1 - 0.05 12.4 0.2 0.061 12.1 0.2 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Baculo_11_kDa PF06143.11 CDJ89857.1 - 0.16 11.5 1.4 0.22 11.1 0.4 1.7 2 0 0 2 2 2 0 Baculovirus 11 kDa family WAPL PF07814.13 CDJ89858.1 - 3.6e-79 266.2 14.9 5e-79 265.7 14.9 1.2 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Histone PF00125.24 CDJ89859.1 - 5.2e-18 65.7 0.0 7.3e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CDJ89859.1 - 4e-12 45.6 0.0 8.3e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CDJ89859.1 - 0.002 18.4 0.0 0.0033 17.7 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CDC50 PF03381.15 CDJ89860.1 - 5.3e-87 291.9 0.0 6.6e-87 291.6 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Glypican PF01153.19 CDJ89861.1 - 6.3e-34 117.7 4.6 7.7e-34 117.5 4.6 1.0 1 0 0 1 1 1 1 Glypican SNF PF00209.18 CDJ89862.1 - 0.017 13.8 0.9 0.023 13.4 0.9 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family HLH PF00010.26 CDJ89863.1 - 8.5e-16 57.7 1.4 8.5e-16 57.7 1.4 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain COE1_HLH PF16423.5 CDJ89863.1 - 8.2e-05 22.2 0.0 0.00016 21.3 0.0 1.5 1 0 0 1 1 1 1 Transcription factor COE1 helix-loop-helix domain KIF1B PF12423.8 CDJ89863.1 - 0.002 18.5 0.0 0.0057 17.1 0.0 1.8 1 0 0 1 1 1 1 Kinesin protein 1B Cep57_CLD PF14073.6 CDJ89863.1 - 0.14 12.2 6.3 0.18 11.8 5.5 1.5 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 Lzipper-MIP1 PF14389.6 CDJ89863.1 - 0.43 10.9 6.3 0.17 12.2 2.2 2.5 3 1 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 TFIIA PF03153.13 CDJ89863.1 - 1.9 8.4 9.5 2.6 8.0 9.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4746 PF15928.5 CDJ89864.1 - 0.0067 15.9 1.3 0.0095 15.4 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) SCVP PF17619.2 CDJ89865.1 - 1.7e-11 44.8 0.0 1.8e-11 44.7 0.0 1.0 1 0 0 1 1 1 1 Secreted clade V proteins SCVP PF17619.2 CDJ89866.1 - 1.1e-11 45.4 0.0 1.2e-11 45.2 0.0 1.0 1 0 0 1 1 1 1 Secreted clade V proteins SCVP PF17619.2 CDJ89867.1 - 3e-13 50.4 0.1 3.4e-13 50.3 0.1 1.0 1 0 0 1 1 1 1 Secreted clade V proteins PY_rept_46 PF09689.10 CDJ89868.1 - 0.23 12.0 0.7 1.6 9.4 1.0 2.1 2 0 0 2 2 2 0 Plasmodium yoelii repeat (PY_rept_46) COMP PF11598.8 CDJ89869.1 - 0.0018 18.7 1.1 0.0039 17.6 0.3 2.0 2 0 0 2 2 2 1 Cartilage oligomeric matrix protein LMBR1 PF04791.16 CDJ89869.1 - 0.03 13.2 2.0 0.033 13.1 2.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Tweety PF04906.13 CDJ89869.1 - 0.031 13.0 0.8 0.04 12.6 0.8 1.1 1 0 0 1 1 1 0 Tweety DUF4200 PF13863.6 CDJ89869.1 - 0.036 14.5 2.0 0.051 14.0 0.2 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Golgin_A5 PF09787.9 CDJ89869.1 - 0.069 12.6 7.0 0.095 12.2 6.8 1.3 1 1 0 1 1 1 0 Golgin subfamily A member 5 DUF948 PF06103.11 CDJ89869.1 - 0.1 12.9 2.3 2.3 8.5 0.1 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2508 PF10704.9 CDJ89869.1 - 0.12 12.5 2.4 8.3 6.7 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2508) Filament PF00038.21 CDJ89869.1 - 0.2 11.2 8.5 2.3 7.7 3.2 2.5 1 1 1 2 2 2 0 Intermediate filament protein ZapB PF06005.12 CDJ89869.1 - 0.26 11.7 0.1 0.26 11.7 0.1 2.5 2 1 0 2 2 2 0 Cell division protein ZapB DUF641 PF04859.12 CDJ89869.1 - 0.51 10.7 5.5 1.4 9.3 1.2 2.6 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) MIP-T3_C PF17749.1 CDJ89869.1 - 0.72 9.8 7.2 1.2 9.0 2.3 2.3 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region CENP-H PF05837.12 CDJ89869.1 - 1.1 9.7 6.5 0.51 10.8 1.7 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DnaJ_C PF01556.18 CDJ89871.1 - 2e-41 141.5 0.1 3.4e-41 140.8 0.1 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CDJ89871.1 - 5.7e-14 52.0 0.8 5.7e-14 52.0 0.8 1.9 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CDJ89871.1 - 1e-13 51.4 18.8 1.7e-13 50.7 18.8 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CDJ89871.1 - 0.15 12.0 14.3 0.22 11.5 3.0 2.4 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CDJ89871.1 - 0.18 11.9 9.8 1.8 8.6 2.9 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 CDJ89871.1 - 5 7.2 10.4 6.8 6.8 3.0 2.5 2 0 0 2 2 2 0 Double zinc ribbon Ribosomal_L14 PF00238.19 CDJ89872.1 - 6.4e-36 123.1 0.1 7.6e-36 122.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PAS PF00989.25 CDJ89872.1 - 0.13 12.3 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 PAS fold Claudin_3 PF06653.11 CDJ89873.1 - 1.9e-17 63.7 12.5 2.5e-17 63.3 12.5 1.2 1 0 0 1 1 1 1 Tight junction protein, Claudin-like PMP22_Claudin PF00822.20 CDJ89873.1 - 4.4e-08 33.2 7.3 7.4e-08 32.4 7.3 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family SUR7 PF06687.12 CDJ89873.1 - 3.8e-07 30.0 8.3 3.8e-07 30.0 8.3 1.6 2 0 0 2 2 2 1 SUR7/PalI family Amastin PF07344.11 CDJ89873.1 - 6.7e-07 29.3 9.7 6.7e-07 29.3 9.7 1.7 1 1 1 2 2 2 1 Amastin surface glycoprotein Chordopox_A13L PF05961.11 CDJ89873.1 - 0.092 13.0 0.0 0.092 13.0 0.0 2.2 2 0 0 2 2 2 0 Chordopoxvirus A13L protein PRA1 PF03208.19 CDJ89873.1 - 0.33 10.6 12.0 0.041 13.5 4.6 2.3 1 1 1 2 2 2 0 PRA1 family protein DUF4293 PF14126.6 CDJ89873.1 - 0.43 10.8 6.5 2.3 8.5 6.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) Syndecan PF01034.20 CDJ89873.1 - 2 8.4 0.0 2 8.4 0.0 2.8 4 0 0 4 4 4 0 Syndecan domain AD PF09793.9 CDJ89874.1 - 5.9e-17 61.6 0.3 1.1e-16 60.7 0.0 1.5 2 0 0 2 2 2 1 Anticodon-binding domain N6-adenineMlase PF10237.9 CDJ89875.1 - 2e-51 174.0 0.1 2.5e-51 173.7 0.1 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase DUF43 PF01861.16 CDJ89875.1 - 0.081 12.1 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain ROQ_II PF18386.1 CDJ89876.1 - 3.5e-34 116.4 0.3 6.9e-34 115.5 0.3 1.5 1 0 0 1 1 1 1 Roquin II domain Torus PF16131.5 CDJ89876.1 - 0.00039 21.1 0.6 0.00079 20.1 0.6 1.4 1 0 0 1 1 1 1 Torus domain zf-CCCH PF00642.24 CDJ89876.1 - 0.00046 20.0 0.5 0.00046 20.0 0.5 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_UBOX PF13445.6 CDJ89876.1 - 0.00052 20.0 7.1 0.0011 18.9 7.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDJ89876.1 - 0.0013 18.8 7.4 0.0042 17.2 7.4 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 CDJ89876.1 - 0.0034 17.5 6.8 0.0034 17.5 6.8 2.7 3 0 0 3 3 3 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 CDJ89876.1 - 0.0092 15.8 4.8 0.025 14.5 4.8 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 CDJ89876.1 - 0.011 15.6 12.1 0.028 14.4 12.1 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf_CCCH_4 PF18345.1 CDJ89876.1 - 0.02 14.9 1.4 0.064 13.3 0.5 2.4 2 0 0 2 2 2 0 Zinc finger domain zf-C3HC4 PF00097.25 CDJ89876.1 - 0.029 14.2 8.4 0.071 13.0 8.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-CCCH_4 PF18044.1 CDJ89876.1 - 0.11 12.3 0.6 0.27 11.1 0.6 1.7 1 0 0 1 1 1 0 CCCH-type zinc finger Prok-RING_4 PF14447.6 CDJ89876.1 - 0.13 12.2 8.6 0.33 10.9 8.6 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF743 PF05332.11 CDJ89876.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF743) zf-RING_2 PF13639.6 CDJ89876.1 - 0.15 12.4 11.4 0.4 11.1 11.4 1.8 1 0 0 1 1 1 0 Ring finger domain F_actin_bind PF08919.10 CDJ89876.1 - 0.16 12.1 0.8 0.84 9.8 0.2 2.3 2 0 0 2 2 2 0 F-actin binding Rtf2 PF04641.12 CDJ89876.1 - 0.19 11.1 1.1 0.45 9.8 1.1 1.6 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C3HC4_2 PF13923.6 CDJ89876.1 - 5.5 6.9 11.5 14 5.6 11.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) GyrI-like PF06445.15 CDJ89877.1 - 0.0044 17.3 0.2 0.028 14.7 0.2 2.1 1 1 0 1 1 1 1 GyrI-like small molecule binding domain GRP PF07172.11 CDJ89878.1 - 6.3e-05 23.6 0.0 7.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Glycine rich protein family TTD PF12148.8 CDJ89879.1 - 0.041 13.8 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Tandem tudor domain within UHRF1 Thioredoxin_7 PF13899.6 CDJ89880.1 - 7.9e-13 48.4 0.0 1.5e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredox_DsbH PF03190.15 CDJ89880.1 - 3.3e-07 30.4 0.1 6.7e-07 29.4 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF255 Dapper PF15268.6 CDJ89880.1 - 0.0054 15.7 25.5 0.006 15.5 25.5 1.0 1 0 0 1 1 1 1 Dapper ShK PF01549.24 CDJ89882.1 - 7.6e-23 80.8 52.9 1.7e-08 34.9 6.3 4.6 5 0 0 5 5 5 4 ShK domain-like PBP PF01161.20 CDJ89883.1 - 0.0041 17.4 0.1 0.075 13.3 0.0 2.3 2 0 0 2 2 2 1 Phosphatidylethanolamine-binding protein G-gamma PF00631.22 CDJ89886.1 - 2.3e-14 53.2 0.2 4.1e-14 52.3 0.2 1.4 1 0 0 1 1 1 1 GGL domain DUF963 PF06131.11 CDJ89886.1 - 0.016 14.6 9.1 0.016 14.6 9.1 2.7 2 1 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) TMEM132D_C PF15706.5 CDJ89886.1 - 0.028 14.2 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term 7TM_GPCR_Srx PF10328.9 CDJ89887.1 - 8.9e-61 205.8 24.5 1.2e-60 205.4 24.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 CDJ89887.1 - 4.6e-09 36.0 15.9 7.5e-09 35.3 15.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_1 PF00001.21 CDJ89887.1 - 2e-06 27.4 14.1 3e-06 26.8 14.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srt PF10321.9 CDJ89887.1 - 0.00017 20.7 16.1 0.00024 20.2 16.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt Serpentine_r_xa PF03383.15 CDJ89887.1 - 0.0044 17.0 0.6 0.0044 17.0 0.6 2.1 1 1 0 2 2 2 1 Caenorhabditis serpentine receptor-like protein, class xa PEPcase_2 PF14010.6 CDJ89887.1 - 0.14 10.7 0.3 0.2 10.2 0.3 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase DUF1786 PF08735.10 CDJ89889.1 - 0.067 12.5 0.0 0.08 12.2 0.0 1.1 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) Cwf_Cwc_15 PF04889.12 CDJ89890.1 - 0.097 12.4 2.3 0.11 12.3 2.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Rootletin PF15035.6 CDJ89891.1 - 0.11 12.5 18.6 0.026 14.6 4.1 2.3 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion SHE3 PF17078.5 CDJ89891.1 - 0.15 11.8 15.1 0.03 14.1 5.8 2.4 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 DUF2681 PF10883.8 CDJ89891.1 - 0.17 12.3 5.1 0.48 10.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF2570 PF10828.8 CDJ89891.1 - 0.37 10.6 5.9 0.7 9.7 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) FapA PF03961.13 CDJ89891.1 - 0.53 8.8 10.2 0.39 9.3 1.5 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A TMPIT PF07851.13 CDJ89891.1 - 3.3 6.9 9.7 0.16 11.2 2.4 1.9 2 0 0 2 2 2 0 TMPIT-like protein DUF948 PF06103.11 CDJ89891.1 - 9.4 6.6 8.2 0.97 9.7 0.6 2.8 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Peptidase_S10 PF00450.22 CDJ89892.1 - 1.9e-81 274.6 5.2 2.3e-81 274.4 5.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase RVT_1 PF00078.27 CDJ89893.1 - 7.6e-06 25.6 0.0 0.00012 21.6 0.0 2.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) KAP PF05804.12 CDJ89894.1 - 7.9e-210 698.6 22.9 4.2e-147 491.3 8.8 2.3 1 1 1 2 2 2 2 Kinesin-associated protein (KAP) DUF2591 PF10765.9 CDJ89894.1 - 9.5e-06 25.9 0.6 0.21 11.8 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2591) Peptidase_S28 PF05577.12 CDJ89894.1 - 0.0064 15.3 0.5 2.7 6.7 0.1 2.2 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Spore_III_AE PF09546.10 CDJ89894.1 - 0.0082 15.4 4.2 1.1 8.3 0.3 2.3 2 0 0 2 2 2 2 Stage III sporulation protein AE (spore_III_AE) putAbiC PF16872.5 CDJ89894.1 - 0.021 15.5 0.2 18 6.1 0.0 2.8 2 0 0 2 2 2 0 Putative phage abortive infection protein Ctf8 PF09696.10 CDJ89894.1 - 0.03 14.7 0.0 8.5 6.7 0.0 2.6 2 0 0 2 2 2 0 Ctf8 CusF_Ec PF11604.8 CDJ89894.1 - 0.12 12.4 0.0 31 4.6 0.0 2.7 2 0 0 2 2 2 0 Copper binding periplasmic protein CusF PROCN PF08083.11 CDJ89894.1 - 0.14 10.9 1.6 3.3 6.3 0.2 2.3 2 0 0 2 2 2 0 PROCN (NUC071) domain Annexin_like PF18411.1 CDJ89894.1 - 0.17 12.2 0.7 14 6.0 0.1 2.5 2 0 0 2 2 2 0 Annexin-like domain ParB_C PF18064.1 CDJ89894.1 - 0.73 10.0 2.5 32 4.8 0.2 2.4 2 0 0 2 2 2 0 Centromere-binding protein ParB C-terminal Arm_2 PF04826.13 CDJ89894.1 - 2.5 7.5 10.8 0.95 8.9 0.3 3.2 3 1 1 4 4 4 0 Armadillo-like Cation_efflux PF01545.21 CDJ89895.1 - 2.1e-13 50.4 10.8 4.8e-13 49.3 10.8 1.6 1 1 0 1 1 1 1 Cation efflux family LRR19-TM PF15176.6 CDJ89895.1 - 0.34 10.9 2.4 0.67 10.0 0.0 2.6 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF1422 PF07226.11 CDJ89895.1 - 0.85 9.7 5.9 4.6 7.3 3.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) DAO PF01266.24 CDJ89897.1 - 9.8e-52 176.7 0.0 1.4e-51 176.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDJ89897.1 - 9.3e-06 25.8 0.0 0.00015 21.9 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CDJ89897.1 - 8.2e-05 22.0 0.0 0.011 14.9 0.0 1.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 CDJ89897.1 - 0.019 15.2 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_2 PF00890.24 CDJ89897.1 - 0.025 13.7 0.0 0.083 12.0 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 CDJ89897.1 - 0.027 13.3 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 CDJ89897.1 - 0.077 13.6 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CDJ89897.1 - 0.12 11.6 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 CDJ89897.1 - 0.18 11.0 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Cadherin PF00028.17 CDJ89898.1 - 3.1e-47 159.0 6.8 3.2e-11 43.5 0.0 10.8 10 1 1 11 11 11 6 Cadherin domain Cadherin_2 PF08266.12 CDJ89898.1 - 3.2e-06 26.9 0.0 22 5.0 0.0 5.9 6 0 0 6 6 6 1 Cadherin-like Cadherin_3 PF16184.5 CDJ89898.1 - 1.8e-05 24.7 1.8 0.18 11.8 0.0 4.5 4 0 0 4 4 4 2 Cadherin-like RET_CLD1 PF17756.1 CDJ89898.1 - 0.0025 18.1 0.0 5.4 7.3 0.0 3.2 2 1 1 3 3 3 2 RET Cadherin like domain 1 MukF_C PF17193.4 CDJ89898.1 - 0.015 15.4 0.3 5.5 7.1 0.0 2.9 2 1 1 3 3 3 0 MukF C-terminal domain Y_Y_Y PF07495.13 CDJ89898.1 - 0.12 12.4 0.0 4.5 7.3 0.0 3.0 2 0 0 2 2 2 0 Y_Y_Y domain Nop14 PF04147.12 CDJ89898.1 - 2.1 6.5 14.1 4.1 5.5 14.1 1.4 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 CDJ89898.1 - 2.3 6.9 8.0 4.9 5.8 8.0 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein WD40 PF00400.32 CDJ89900.1 - 1.1e-22 79.9 14.9 6.2e-05 23.7 0.1 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ89900.1 - 0.0011 19.2 0.0 1.8 8.9 0.0 2.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 CDJ89900.1 - 0.0066 16.5 0.0 0.075 13.1 0.0 2.7 2 2 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 CDJ89900.1 - 0.12 11.7 0.1 0.46 9.8 0.1 1.9 2 0 0 2 2 2 0 WD40-like domain fn1 PF00039.18 CDJ89901.1 - 6.3 7.1 14.2 6.5 7.0 2.4 3.7 3 0 0 3 3 3 0 Fibronectin type I domain Pkinase PF00069.25 CDJ89904.1 - 5.1e-69 232.6 0.0 7.2e-69 232.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ89904.1 - 8.1e-34 117.1 0.0 1.2e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CDJ89904.1 - 7.2e-08 33.0 5.2 2.3e-07 31.4 5.2 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 CDJ89904.1 - 1.3e-05 24.7 0.1 4e-05 23.1 0.0 1.8 2 1 0 2 2 2 1 Kinase-like FTA2 PF13095.6 CDJ89904.1 - 0.00032 20.4 0.1 0.73 9.4 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CDJ89904.1 - 0.0012 17.8 0.0 0.0018 17.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDJ89904.1 - 0.005 16.2 0.3 0.019 14.3 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDJ89904.1 - 0.13 11.2 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 CDJ89904.1 - 0.16 11.0 0.0 0.34 9.9 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 RT_RNaseH PF17917.1 CDJ89905.1 - 2.1e-32 111.5 0.0 2.4e-31 108.1 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ89905.1 - 1.1e-26 92.8 0.0 4.3e-26 90.9 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ89905.1 - 5.2e-25 88.0 0.0 1.3e-24 86.6 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ89905.1 - 3.7e-17 62.2 0.2 8.3e-17 61.1 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CDJ89905.1 - 5.2e-06 26.1 0.0 5.6e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain DDE_3 PF13358.6 CDJ89905.1 - 0.00095 18.9 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Sigma70_ner PF04546.13 CDJ89905.1 - 0.013 15.3 6.3 0.78 9.6 5.2 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region zf-H2C2 PF09337.10 CDJ89905.1 - 0.024 14.9 0.0 0.054 13.7 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger DMAP_binding PF06464.11 CDJ89905.1 - 0.025 15.4 0.1 0.025 15.4 0.1 2.0 2 0 0 2 2 2 0 DMAP1-binding Domain Mid2 PF04478.12 CDJ89905.1 - 0.21 11.4 0.0 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor 7tm_1 PF00001.21 CDJ89906.1 - 1.4e-13 50.8 23.3 2.4e-13 50.0 23.3 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDJ89906.1 - 6.6e-10 38.8 26.9 9.5e-10 38.3 26.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Amino_oxidase PF01593.24 CDJ89907.1 - 3.5e-12 46.4 0.0 4.9e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ89907.1 - 1.2e-05 25.4 0.0 3.1e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GLF PF03275.13 CDJ89907.1 - 0.0048 16.6 0.3 1.3 8.7 0.1 2.3 2 0 0 2 2 2 2 UDP-galactopyranose mutase NAGidase PF07555.13 CDJ89908.1 - 1.2e-28 100.3 0.0 1.8e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 beta-N-acetylglucosaminidase zf-CCHC PF00098.23 CDJ89909.1 - 0.0001 22.2 2.0 0.0001 22.2 2.0 2.1 2 0 0 2 2 2 1 Zinc knuckle gag-asp_proteas PF13975.6 CDJ89909.1 - 0.00025 21.5 0.0 0.0011 19.5 0.0 2.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease NAGidase PF07555.13 CDJ89910.1 - 9.4e-44 149.9 0.0 1.1e-43 149.6 0.0 1.0 1 0 0 1 1 1 1 beta-N-acetylglucosaminidase zf-C4 PF00105.18 CDJ89911.1 - 1.2e-29 102.5 15.1 2.1e-29 101.7 15.1 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ89911.1 - 1.5e-20 73.6 0.0 2.5e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor KN_motif PF12075.8 CDJ89912.1 - 7e-09 35.3 1.6 1e-08 34.8 0.0 2.1 2 0 0 2 2 2 1 KN motif Filo_glycop PF01611.16 CDJ89912.1 - 0.12 11.3 0.1 0.16 10.8 0.1 1.1 1 0 0 1 1 1 0 Filovirus glycoprotein Nuc_rec_co-act PF08815.10 CDJ89912.1 - 0.17 11.7 0.9 0.25 11.2 0.1 1.7 2 0 0 2 2 2 0 Nuclear receptor coactivator zf-CCHC PF00098.23 CDJ89913.1 - 1.3e-10 40.8 36.1 0.00026 20.9 1.4 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ89913.1 - 0.31 10.8 29.9 0.62 9.9 0.6 4.3 4 0 0 4 4 4 0 Zinc knuckle Histone PF00125.24 CDJ89914.1 - 1.7e-28 99.6 0.0 1.7e-28 99.6 0.0 2.4 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Sec2p PF06428.11 CDJ89914.1 - 0.021 14.8 0.7 0.17 11.9 0.0 2.4 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p CBFD_NFYB_HMF PF00808.23 CDJ89914.1 - 0.045 14.0 0.3 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 CDJ89914.1 - 0.046 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold LRIF1 PF15741.5 CDJ89914.1 - 1.5 7.2 3.7 2 6.9 3.7 1.1 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 SCVP PF17619.2 CDJ89915.1 - 2.7e-23 82.6 2.6 1.2e-18 67.8 0.7 2.2 2 0 0 2 2 2 2 Secreted clade V proteins SM-ATX PF14438.6 CDJ89916.1 - 1.5e-16 60.2 0.1 3e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain LsmAD PF06741.13 CDJ89916.1 - 2.6e-06 27.9 6.0 2.6e-06 27.9 6.0 2.2 2 0 0 2 2 2 1 LsmAD domain PAM2 PF07145.15 CDJ89916.1 - 0.011 15.3 0.9 0.044 13.5 0.9 2.1 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Prion_bPrPp PF11587.8 CDJ89918.1 - 0.032 14.1 0.1 0.052 13.4 0.1 1.4 1 0 0 1 1 1 0 Major prion protein bPrPp - N terminal Pex14_N PF04695.13 CDJ89918.1 - 0.082 13.6 3.8 0.093 13.4 3.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MSA-2c PF12238.8 CDJ89918.1 - 0.14 12.1 0.4 0.16 11.9 0.4 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c Cullin PF00888.22 CDJ89919.1 - 4e-179 597.2 10.7 5.3e-179 596.8 10.7 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CDJ89919.1 - 8.1e-21 73.8 0.8 8.1e-21 73.8 0.8 2.4 3 0 0 3 3 3 1 Cullin protein neddylation domain Ribosomal_L6e PF01159.19 CDJ89919.1 - 2.5 8.7 8.6 0.88 10.1 4.6 2.3 2 0 0 2 2 2 0 Ribosomal protein L6e TIMP PF00965.17 CDJ89921.1 - 1.9e-17 63.7 0.0 2.3e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.21 CDJ89921.1 - 2e-08 34.0 0.0 2.5e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 UNC-6/NTR/C345C module BTB PF00651.31 CDJ89922.1 - 1.1e-30 106.1 1.9 2.5e-30 105.0 0.8 2.1 1 1 1 2 2 2 1 BTB/POZ domain MATH PF00917.26 CDJ89922.1 - 1.9e-06 28.0 0.1 3.8e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 MATH domain BACK PF07707.15 CDJ89922.1 - 0.00075 19.6 0.6 0.016 15.3 0.0 3.0 3 0 0 3 3 3 1 BTB And C-terminal Kelch bZIP_2 PF07716.15 CDJ89923.1 - 0.12 12.5 3.2 0.31 11.2 3.2 1.7 1 0 0 1 1 1 0 Basic region leucine zipper MIF4G PF02854.19 CDJ89924.1 - 0.00077 19.1 0.2 0.0016 18.1 0.2 1.6 1 0 0 1 1 1 1 MIF4G domain PAM2 PF07145.15 CDJ89924.1 - 0.1 12.4 4.6 0.18 11.6 3.6 1.9 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Ig_3 PF13927.6 CDJ89925.1 - 6.1e-129 420.9 17.9 5.7e-11 42.9 0.1 14.5 14 0 0 14 14 14 14 Immunoglobulin domain Ig_2 PF13895.6 CDJ89925.1 - 5.8e-113 369.4 0.1 6.6e-11 42.4 0.0 14.4 13 1 1 14 14 14 14 Immunoglobulin domain I-set PF07679.16 CDJ89925.1 - 4.4e-109 356.8 0.0 5.9e-10 39.1 0.0 14.9 14 0 0 14 14 14 14 Immunoglobulin I-set domain ig PF00047.25 CDJ89925.1 - 3.1e-84 277.2 0.1 5.4e-09 36.1 0.0 15.3 14 2 0 14 14 14 12 Immunoglobulin domain Laminin_G_2 PF02210.24 CDJ89925.1 - 1.7e-52 177.3 0.2 2.9e-26 92.5 0.4 3.8 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.23 CDJ89925.1 - 1.8e-47 160.8 0.0 1.7e-27 96.2 0.1 3.6 3 0 0 3 3 3 3 Laminin G domain Laminin_B PF00052.18 CDJ89925.1 - 4.9e-38 130.1 0.0 9.6e-38 129.1 0.0 1.5 1 0 0 1 1 1 1 Laminin B (Domain IV) Laminin_EGF PF00053.24 CDJ89925.1 - 8e-25 86.7 105.7 1.8e-08 34.3 17.6 7.5 6 1 1 7 7 7 7 Laminin EGF domain Ig_6 PF18452.1 CDJ89925.1 - 3.4e-21 74.5 0.0 0.55 9.8 0.0 13.1 14 0 0 14 14 14 4 Immunoglobulin domain V-set PF07686.17 CDJ89925.1 - 9e-19 67.7 34.6 3.7 7.8 0.0 20.2 16 9 8 25 25 25 5 Immunoglobulin V-set domain Izumo-Ig PF16706.5 CDJ89925.1 - 4.4e-06 26.7 3.5 17 5.5 0.0 9.2 11 0 0 11 11 10 0 Izumo-like Immunoglobulin domain Plasmod_Pvs28 PF06247.11 CDJ89925.1 - 0.00057 20.1 0.9 0.00057 20.1 0.9 5.6 5 0 0 5 5 4 1 Pvs28 EGF domain V-set_CD47 PF08204.11 CDJ89925.1 - 0.028 14.4 5.4 34 4.4 0.0 6.7 8 0 0 8 8 8 0 CD47 immunoglobulin-like domain Peptidase_M13 PF01431.21 CDJ89926.1 - 4.1e-76 255.2 0.1 9.1e-76 254.0 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 CDJ89926.1 - 6e-70 236.8 7.0 6e-70 236.8 7.0 1.9 2 0 0 2 2 2 1 Peptidase family M13 DUF2340 PF10209.9 CDJ89926.1 - 0.91 10.0 5.5 1.2 9.6 2.2 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2340) GMP_PDE_delta PF05351.11 CDJ89927.1 - 2e-45 154.6 0.1 2.6e-45 154.3 0.1 1.1 1 0 0 1 1 1 1 GMP-PDE, delta subunit RNA_pol_Rpb4 PF03874.16 CDJ89928.1 - 2.3e-05 24.7 1.0 3.4e-05 24.1 1.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 MAD PF05557.13 CDJ89929.1 - 3.5e-13 48.8 23.1 8.1e-10 37.7 1.1 2.1 1 1 1 2 2 2 2 Mitotic checkpoint protein CENP-F_leu_zip PF10473.9 CDJ89929.1 - 2.5e-06 27.5 25.7 0.0032 17.5 4.4 3.5 2 1 1 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 CDJ89929.1 - 8e-05 23.2 25.0 0.0027 18.2 24.4 2.3 1 1 1 2 2 2 1 Fez1 ATG16 PF08614.11 CDJ89929.1 - 0.00013 22.3 28.6 0.00085 19.6 15.8 2.9 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) CCDC144C PF14915.6 CDJ89929.1 - 0.00033 19.9 13.8 0.00033 19.9 13.8 2.3 2 0 0 2 2 2 1 CCDC144C protein coiled-coil region GAS PF13851.6 CDJ89929.1 - 0.0011 18.4 27.7 0.0062 15.9 6.4 3.4 1 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 CDJ89929.1 - 0.0014 18.0 20.8 0.0026 17.1 2.3 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF3450) APG6_N PF17675.1 CDJ89929.1 - 0.0015 19.1 35.3 0.034 14.7 7.2 3.6 1 1 2 3 3 3 2 Apg6 coiled-coil region KLRAQ PF10205.9 CDJ89929.1 - 0.0034 17.6 2.2 0.0034 17.6 2.2 3.9 1 1 2 3 3 3 1 Predicted coiled-coil domain-containing protein HAP1_N PF04849.13 CDJ89929.1 - 0.004 16.4 11.7 0.004 16.4 11.7 3.0 1 1 2 3 3 2 1 HAP1 N-terminal conserved region HOOK PF05622.12 CDJ89929.1 - 0.011 14.0 25.7 0.017 13.3 25.7 1.2 1 0 0 1 1 1 0 HOOK protein DUF2203 PF09969.9 CDJ89929.1 - 0.02 15.6 13.2 0.88 10.3 0.4 3.3 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) DivIC PF04977.15 CDJ89929.1 - 0.037 13.8 18.6 0.16 11.8 1.0 4.1 3 1 1 4 4 4 0 Septum formation initiator ERM PF00769.19 CDJ89929.1 - 0.039 13.8 31.8 0.3 10.9 31.1 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family NPV_P10 PF05531.12 CDJ89929.1 - 0.09 13.2 5.3 1.2 9.7 0.2 3.3 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein WEMBL PF05701.11 CDJ89929.1 - 0.11 11.2 25.3 0.87 8.2 25.5 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Fungal_TACC PF12709.7 CDJ89929.1 - 0.16 12.4 15.6 0.28 11.6 0.9 3.7 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins FUSC PF04632.12 CDJ89929.1 - 0.19 10.2 7.5 0.044 12.3 3.9 1.6 1 1 0 1 1 1 0 Fusaric acid resistance protein family BrnA_antitoxin PF14384.6 CDJ89929.1 - 0.22 12.0 1.7 0.38 11.3 0.4 2.2 2 0 0 2 2 1 0 BrnA antitoxin of type II toxin-antitoxin system UPF0242 PF06785.11 CDJ89929.1 - 0.43 10.7 27.9 0.59 10.2 9.4 3.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Sec34 PF04136.15 CDJ89929.1 - 0.55 10.1 17.9 0.94 9.3 1.1 3.3 2 1 1 3 3 3 0 Sec34-like family NBP1 PF08537.10 CDJ89929.1 - 0.65 9.3 18.2 1.8 7.9 8.7 2.2 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 KASH_CCD PF14662.6 CDJ89929.1 - 0.68 9.7 25.0 0.092 12.6 12.7 3.2 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH Snapin_Pallidin PF14712.6 CDJ89929.1 - 0.76 10.2 16.6 0.11 12.9 5.4 3.6 2 1 3 5 5 5 0 Snapin/Pallidin COG2 PF06148.11 CDJ89929.1 - 0.79 9.8 12.3 2.7 8.1 0.7 3.3 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Filament PF00038.21 CDJ89929.1 - 0.83 9.2 27.9 0.24 10.9 6.6 3.2 1 1 1 3 3 3 0 Intermediate filament protein DUF641 PF04859.12 CDJ89929.1 - 1.2 9.5 18.7 1.4 9.2 2.9 3.6 2 1 0 3 3 3 0 Plant protein of unknown function (DUF641) Occludin_ELL PF07303.13 CDJ89929.1 - 1.4 9.7 13.7 8.3 7.2 1.1 3.7 2 1 1 3 3 3 0 Occludin homology domain ADIP PF11559.8 CDJ89929.1 - 1.4 9.0 29.5 1.2 9.2 3.2 3.4 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding AATF-Che1 PF13339.6 CDJ89929.1 - 1.5 9.5 18.8 4.9 7.8 9.9 3.0 1 1 2 3 3 3 0 Apoptosis antagonizing transcription factor TSNAXIP1_N PF15739.5 CDJ89929.1 - 1.7 9.0 14.3 0.16 12.4 0.7 3.6 3 0 0 3 3 3 0 Translin-associated factor X-interacting N-terminus Sec8_exocyst PF04048.14 CDJ89929.1 - 2.8 7.8 7.6 1.4 8.8 0.7 3.0 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain THOC7 PF05615.13 CDJ89929.1 - 3 8.1 28.6 0.092 13.0 3.2 3.7 3 1 1 4 4 3 0 Tho complex subunit 7 TMF_TATA_bd PF12325.8 CDJ89929.1 - 3.3 8.0 28.7 0.058 13.6 8.5 3.5 1 1 1 2 2 1 0 TATA element modulatory factor 1 TATA binding BST2 PF16716.5 CDJ89929.1 - 4.4 8.0 25.5 0.97 10.1 0.2 4.6 2 1 2 4 4 3 0 Bone marrow stromal antigen 2 Cnn_1N PF07989.11 CDJ89929.1 - 4.6 7.5 20.7 7.1 6.9 0.3 3.9 2 1 0 3 3 3 0 Centrosomin N-terminal motif 1 FlxA PF14282.6 CDJ89929.1 - 4.7 7.3 17.0 13 5.8 2.9 3.6 2 1 1 3 3 3 0 FlxA-like protein Spc7 PF08317.11 CDJ89929.1 - 6.1 5.6 30.2 0.058 12.3 14.7 2.6 1 1 0 2 2 2 0 Spc7 kinetochore protein Tropomyosin PF00261.20 CDJ89929.1 - 6.1 6.1 31.6 4.6e+03 -3.3 31.8 3.1 1 1 0 1 1 0 0 Tropomyosin Laminin_II PF06009.12 CDJ89929.1 - 6.6 6.8 13.7 3 7.9 4.3 3.0 2 1 1 3 3 3 0 Laminin Domain II LRRFIP PF09738.9 CDJ89929.1 - 6.6 6.1 27.2 19 4.6 3.3 3.4 1 1 1 2 2 2 0 LRRFIP family Fmp27_WPPW PF10359.9 CDJ89929.1 - 6.9 5.4 24.1 3.4 6.4 14.5 2.9 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Cep57_CLD_2 PF14197.6 CDJ89929.1 - 9.6 6.4 28.8 0.088 12.9 9.7 4.2 3 2 0 3 3 3 0 Centrosome localisation domain of PPC89 zf-C2HC5 PF06221.13 CDJ89930.1 - 4.6e-12 45.7 10.6 1.1e-11 44.5 10.6 1.7 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DUF1542 PF07564.11 CDJ89930.1 - 0.1 12.7 0.1 0.3 11.2 0.1 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Mito_carr PF00153.27 CDJ89931.1 - 1.1e-08 34.8 0.7 4.8e-05 23.2 0.1 2.5 3 0 0 3 3 3 2 Mitochondrial carrier protein RRM_1 PF00076.22 CDJ89932.1 - 2.3e-60 200.3 0.0 7.1e-19 67.4 0.0 3.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ89932.1 - 2.8e-09 36.6 0.0 4e-05 23.2 0.0 3.2 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ89932.1 - 2.2e-05 24.2 0.0 0.24 11.3 0.0 2.7 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_2 PF04059.12 CDJ89932.1 - 0.068 13.4 0.1 12 6.2 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif 2 RRM_9 PF18444.1 CDJ89932.1 - 0.086 12.7 0.1 3.9 7.4 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif RNase_T PF00929.24 CDJ89933.1 - 1.9e-33 116.3 0.0 2.2e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 CDJ89933.1 - 8.7e-05 22.6 0.0 0.00013 22.0 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like Plk4_PB1 PF18190.1 CDJ89933.1 - 0.028 14.6 0.4 0.64 10.2 0.1 2.3 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 1 Hpt PF01627.23 CDJ89934.1 - 0.0033 17.7 0.6 0.0041 17.3 0.6 1.1 1 0 0 1 1 1 1 Hpt domain Trimer_CC PF08954.11 CDJ89934.1 - 0.0087 15.6 5.4 0.22 11.1 0.5 2.2 2 0 0 2 2 2 2 Trimerisation motif Fib_alpha PF08702.10 CDJ89934.1 - 0.012 15.8 2.2 0.015 15.5 2.2 1.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc29 PF17082.5 CDJ89934.1 - 0.02 14.8 0.3 0.021 14.7 0.3 1.0 1 0 0 1 1 1 0 Spindle Pole Component 29 BLOC1_2 PF10046.9 CDJ89934.1 - 0.023 15.0 1.3 0.054 13.8 1.4 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4164 PF13747.6 CDJ89934.1 - 0.024 14.9 1.4 0.029 14.7 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) TMF_DNA_bd PF12329.8 CDJ89934.1 - 0.027 14.4 1.6 0.035 14.1 1.6 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF1840 PF08895.11 CDJ89934.1 - 0.038 14.3 0.4 0.046 14.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) WD40_alt PF14077.6 CDJ89934.1 - 0.049 13.5 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif ABC_tran_CTD PF16326.5 CDJ89934.1 - 0.062 13.6 7.1 0.16 12.3 7.1 1.6 1 1 0 1 1 1 0 ABC transporter C-terminal domain DivIC PF04977.15 CDJ89934.1 - 0.063 13.1 4.9 0.041 13.6 2.6 1.7 1 1 1 2 2 2 0 Septum formation initiator Swi5 PF07061.11 CDJ89934.1 - 0.067 13.3 2.0 0.094 12.8 2.0 1.3 1 0 0 1 1 1 0 Swi5 DUF1192 PF06698.11 CDJ89934.1 - 0.2 11.8 4.9 2 8.5 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) CCM2_C PF16545.5 CDJ89935.1 - 7e-08 32.9 0.0 8.9e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Cerebral cavernous malformation protein, harmonin-homology PrmC_N PF17827.1 CDJ89935.1 - 0.063 13.9 1.8 0.34 11.5 0.1 2.2 1 1 1 2 2 2 0 PrmC N-terminal domain Lectin_C PF00059.21 CDJ89936.1 - 2.7e-16 60.3 1.3 5.1e-16 59.3 1.3 1.4 1 0 0 1 1 1 1 Lectin C-type domain CYLD_phos_site PF16607.5 CDJ89936.1 - 0.093 12.6 0.0 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 Phosphorylation region of CYLD, unstructured VWA PF00092.28 CDJ89937.1 - 7.1e-14 52.4 0.6 2.7e-10 40.8 0.1 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 CDJ89937.1 - 5.7e-08 33.4 0.3 6.7e-05 23.5 0.1 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain Orthopox_A5L PF06193.11 CDJ89937.1 - 5.3 6.4 14.3 9.9 5.5 14.3 1.4 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like LBP_BPI_CETP_C PF02886.17 CDJ89938.1 - 5.4e-31 107.9 0.0 8.7e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 CDJ89938.1 - 0.015 14.9 0.0 0.034 13.7 0.0 1.6 1 0 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain SNF PF00209.18 CDJ89939.1 - 1.4e-81 274.8 16.3 1.5e-81 274.7 16.3 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family PIG-P PF08510.12 CDJ89939.1 - 7 6.6 15.1 0.19 11.7 7.4 2.4 3 0 0 3 3 3 0 PIG-P Copine PF07002.16 CDJ89940.1 - 4.7e-43 147.2 0.0 6.5e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Copine Ribosomal_S8e PF01201.22 CDJ89940.1 - 0.062 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S8e MBOAT PF03062.19 CDJ89941.1 - 2.6e-59 201.3 16.0 7.1e-59 199.9 16.0 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Phlebovirus_G2 PF07245.11 CDJ89942.1 - 2.6e-17 62.5 25.8 3.6e-17 62.1 22.6 2.4 2 1 0 2 2 2 1 Phlebovirus glycoprotein G2 rve PF00665.26 CDJ89942.1 - 5.7e-14 52.3 0.0 1.4e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF5641 PF18701.1 CDJ89942.1 - 8e-09 35.6 0.2 1.9e-08 34.4 0.2 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5641) rve_3 PF13683.6 CDJ89942.1 - 0.003 17.3 0.0 0.0086 15.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Consortin_C PF15281.6 CDJ89942.1 - 0.012 15.6 0.3 3.4 7.7 0.1 2.8 3 0 0 3 3 3 0 Consortin C-terminus Peptidase_A17 PF05380.13 CDJ89943.1 - 1.7e-14 54.2 0.1 4.4e-14 52.8 0.0 1.7 2 0 0 2 2 2 1 Pao retrotransposon peptidase RVT_1 PF00078.27 CDJ89943.1 - 3.3e-10 39.9 0.1 8e-10 38.6 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1758 PF05585.12 CDJ89943.1 - 0.046 13.5 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) CAP PF00188.26 CDJ89944.1 - 1.6e-08 35.5 0.1 2.3e-08 34.9 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ89944.1 - 0.054 13.8 0.3 0.1 12.9 0.3 1.7 1 1 0 1 1 1 0 Ancylostoma-associated secreted protein related MOR2-PAG1_C PF14225.6 CDJ89945.1 - 1.8e-46 159.1 2.1 4.1e-46 157.9 2.1 1.7 1 0 0 1 1 1 1 Cell morphogenesis C-terminal T-box PF00907.22 CDJ89946.1 - 7.5e-20 72.0 0.7 9.6e-20 71.6 0.7 1.2 1 0 0 1 1 1 1 T-box Astacin PF01400.24 CDJ89948.1 - 1.8e-38 132.1 0.7 2.4e-38 131.7 0.7 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Astacin PF01400.24 CDJ89949.1 - 3.9e-48 163.6 0.1 4.9e-48 163.3 0.1 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Cas9-BH PF16593.5 CDJ89949.1 - 0.42 10.4 2.2 0.7 9.7 2.2 1.3 1 0 0 1 1 1 0 Bridge helix of CRISPR-associated endonuclease Cas9 Astacin PF01400.24 CDJ89950.1 - 2.8e-12 46.7 0.1 4.8e-12 45.9 0.1 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) ABC_membrane PF00664.23 CDJ89952.1 - 5.2e-36 124.7 14.0 5.2e-36 124.7 14.0 2.0 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ89952.1 - 2.9e-32 112.1 0.0 5.2e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CDJ89952.1 - 3.9e-05 23.2 0.0 0.00041 19.8 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CDJ89952.1 - 0.002 18.0 0.1 0.0063 16.4 0.1 1.7 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CDJ89952.1 - 0.0029 17.6 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 CDJ89952.1 - 0.0032 17.9 0.1 0.01 16.2 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CDJ89952.1 - 0.007 16.6 0.0 0.059 13.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CDJ89952.1 - 0.023 14.4 0.0 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 CDJ89952.1 - 0.024 14.8 0.4 0.42 10.9 0.4 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit End_beta_barrel PF12195.8 CDJ89952.1 - 0.08 12.9 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Beta barrel domain of bacteriophage endosialidase SAP PF02037.27 CDJ89953.1 - 1.9e-10 40.3 1.7 6.2e-10 38.6 1.7 2.0 1 0 0 1 1 1 1 SAP domain HEAT_EZ PF13513.6 CDJ89953.1 - 0.0082 16.6 0.5 0.87 10.2 0.1 3.2 3 0 0 3 3 3 1 HEAT-like repeat Ipi1_N PF12333.8 CDJ89953.1 - 0.0095 16.5 0.1 0.0095 16.5 0.1 3.7 4 0 0 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation VWA_2 PF13519.6 CDJ89954.1 - 0.033 14.8 1.1 0.33 11.6 0.1 2.9 3 0 0 3 3 3 0 von Willebrand factor type A domain EGF_2 PF07974.13 CDJ89954.1 - 0.083 13.3 83.0 0.098 13.0 5.1 8.5 7 1 1 8 8 8 0 EGF-like domain Metallophos PF00149.28 CDJ89955.1 - 1.2e-28 101.0 0.0 1.5e-28 100.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_C13 PF01650.18 CDJ89956.1 - 2.5e-49 168.1 0.3 3.5e-42 144.7 0.2 2.2 1 1 1 2 2 2 2 Peptidase C13 family DUF384 PF04064.13 CDJ89956.1 - 0.1 12.5 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF384) DinB_2 PF12867.7 CDJ89957.1 - 0.051 14.1 0.4 0.15 12.6 0.0 1.9 1 1 1 2 2 2 0 DinB superfamily Peptidase_C13 PF01650.18 CDJ89958.1 - 4.6e-34 118.1 0.0 6.7e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family TMF_TATA_bd PF12325.8 CDJ89958.1 - 0.12 12.6 1.4 12 6.2 0.4 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Peptidase_C13 PF01650.18 CDJ89961.1 - 6.5e-97 324.0 0.2 9.2e-97 323.5 0.2 1.2 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C13 PF01650.18 CDJ89962.1 - 1.9e-104 348.7 0.1 2.6e-104 348.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family DUF1488 PF07369.11 CDJ89962.1 - 0.18 11.8 0.4 5.7 7.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) 7TM_GPCR_Sri PF10327.9 CDJ89963.1 - 0.023 13.9 0.1 0.03 13.5 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri Peptidase_C13 PF01650.18 CDJ89964.1 - 9.2e-108 359.6 0.1 1.3e-107 359.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase C13 family ABC_membrane PF00664.23 CDJ89965.1 - 9.3e-53 179.6 3.2 1.3e-52 179.2 3.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ89965.1 - 3.9e-37 127.8 0.0 7.8e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CDJ89965.1 - 2.3e-08 33.7 1.9 5.1e-05 22.8 0.1 2.6 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDJ89965.1 - 2.2e-06 28.1 0.0 5.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDJ89965.1 - 4.6e-06 26.9 0.1 2.8e-05 24.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CDJ89965.1 - 0.00087 19.0 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 CDJ89965.1 - 0.0023 17.5 0.1 0.062 12.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CDJ89965.1 - 0.0069 16.3 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 CDJ89965.1 - 0.008 15.5 0.0 0.022 14.1 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.29 CDJ89965.1 - 0.013 15.9 0.6 0.55 10.7 0.3 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 CDJ89965.1 - 0.013 14.3 0.4 0.44 9.3 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_21 PF13304.6 CDJ89965.1 - 0.014 15.2 0.1 0.12 12.1 0.0 2.2 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CDJ89965.1 - 0.015 15.8 0.0 0.042 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CDJ89965.1 - 0.045 14.3 0.0 0.17 12.5 0.0 2.0 2 1 0 2 2 1 0 AAA domain DUF87 PF01935.17 CDJ89965.1 - 0.047 13.8 0.1 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_5 PF07728.14 CDJ89965.1 - 0.059 13.4 0.0 0.47 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF3987 PF13148.6 CDJ89965.1 - 0.06 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DEAD PF00270.29 CDJ89965.1 - 0.064 13.0 0.0 0.84 9.4 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_33 PF13671.6 CDJ89965.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 CDJ89965.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.9 CDJ89965.1 - 0.15 11.3 0.1 0.38 9.9 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) 2-oxoacid_dh PF00198.23 CDJ89966.1 - 1.5e-79 266.7 0.6 1.9e-79 266.4 0.6 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CDJ89966.1 - 2.2e-18 65.8 0.6 4.1e-18 65.0 0.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CDJ89966.1 - 4.8e-05 23.1 0.1 0.00042 20.1 0.0 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like GCV_H PF01597.19 CDJ89966.1 - 0.00055 19.8 0.2 0.0011 18.8 0.2 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_D23 PF16576.5 CDJ89966.1 - 0.0057 15.9 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion RnfC_N PF13375.6 CDJ89966.1 - 0.062 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain RNase_T PF00929.24 CDJ89967.1 - 0.0094 16.5 0.0 0.66 10.5 0.0 2.4 2 0 0 2 2 2 2 Exonuclease VRR_NUC PF08774.11 CDJ89969.1 - 3.8e-25 88.0 0.0 8.7e-25 86.9 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain TLD PF07534.16 CDJ89970.1 - 9.8e-30 103.6 0.0 1.7e-29 102.9 0.0 1.4 1 0 0 1 1 1 1 TLD DivIC PF04977.15 CDJ89971.1 - 0.0023 17.7 0.7 0.044 13.5 0.0 2.4 2 0 0 2 2 2 1 Septum formation initiator RT_RNaseH PF17917.1 CDJ89971.1 - 0.057 13.7 1.8 0.32 11.3 0.9 2.6 2 1 1 3 3 3 0 RNase H-like domain found in reverse transcriptase LysM PF01476.20 CDJ89972.1 - 4.7e-09 36.2 0.0 8.4e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 LysM domain GRAM PF02893.20 CDJ89972.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 GRAM domain RVT_1 PF00078.27 CDJ89973.1 - 2.2e-14 53.5 0.0 6.3e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cullin PF00888.22 CDJ89973.1 - 0.062 11.9 0.0 0.078 11.6 0.0 1.2 1 0 0 1 1 1 0 Cullin family WD40 PF00400.32 CDJ89974.1 - 4.3e-19 68.5 17.7 0.025 15.5 0.2 10.2 11 0 0 11 11 11 5 WD domain, G-beta repeat WD40_like PF17005.5 CDJ89974.1 - 1.6e-05 24.4 0.0 0.021 14.1 0.0 2.7 3 0 0 3 3 3 2 WD40-like domain ANAPC4_WD40 PF12894.7 CDJ89974.1 - 1.9e-05 24.8 0.0 0.0076 16.5 0.0 4.0 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 CDJ89974.1 - 0.078 12.3 0.1 3.8 6.7 0.0 3.4 4 0 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal GMP_synt_C PF00958.22 CDJ89974.1 - 0.11 12.5 0.7 2.4 8.3 0.2 2.4 2 0 0 2 2 2 0 GMP synthase C terminal domain ARGLU PF15346.6 CDJ89976.1 - 6.6e-20 71.5 28.6 6.6e-20 71.5 28.6 2.1 2 0 0 2 2 2 1 Arginine and glutamate-rich 1 LIM PF00412.22 CDJ89977.1 - 3.3e-15 56.1 23.3 2.5e-09 37.2 8.4 2.3 2 0 0 2 2 2 2 LIM domain SHNi-TPR PF10516.9 CDJ89979.1 - 0.089 12.3 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 SHNi-TPR UAA PF08449.11 CDJ89980.1 - 8.1e-86 287.9 20.5 9.3e-86 287.7 20.5 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CDJ89980.1 - 0.00029 21.0 11.2 0.00029 21.0 11.2 2.2 2 0 0 2 2 2 2 EamA-like transporter family TraX PF05857.11 CDJ89980.1 - 0.0043 17.2 3.6 0.0043 17.2 3.6 2.2 2 1 0 2 2 2 1 TraX protein DUF3671 PF12420.8 CDJ89980.1 - 0.14 12.3 0.3 0.14 12.3 0.3 2.9 2 1 0 2 2 2 0 Protein of unknown function Stevor PF17410.2 CDJ89980.1 - 0.29 10.7 1.1 0.43 10.1 1.1 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Renin_r PF07850.14 CDJ89980.1 - 0.48 11.0 1.9 0.77 10.4 0.2 2.2 2 0 0 2 2 2 0 Renin receptor-like protein DUF2663 PF10864.8 CDJ89980.1 - 3.6 8.0 9.5 16 5.9 0.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2663) Calcipressin PF04847.12 CDJ89981.1 - 2.9e-37 128.2 0.2 3.8e-37 127.8 0.2 1.2 1 0 0 1 1 1 1 Calcipressin Gemin7 PF11095.8 CDJ89982.1 - 1.5e-20 72.8 0.1 1.9e-20 72.6 0.1 1.1 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) DUF150_C PF17384.2 CDJ89982.1 - 0.18 12.0 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain Glycolytic PF00274.19 CDJ89983.1 - 9.5e-178 590.2 0.1 1.1e-177 590.0 0.1 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Sybindin PF04099.12 CDJ89984.1 - 6.5e-30 103.9 0.0 7.2e-30 103.8 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 CDJ89984.1 - 2e-08 34.4 0.0 2.3e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Band_7 PF01145.25 CDJ89985.1 - 3.1e-31 108.8 2.0 4.8e-31 108.1 2.0 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CDJ89985.1 - 0.00086 19.1 0.2 0.0013 18.5 0.2 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family GP68 PF17469.2 CDJ89985.1 - 0.066 13.6 0.5 0.18 12.2 0.2 1.9 2 0 0 2 2 2 0 Phage protein Gp68 Clathrin_H_link PF13838.6 CDJ89985.1 - 0.12 12.3 0.9 1.2 9.1 0.2 2.3 2 0 0 2 2 2 0 Clathrin-H-link Pal1 PF08316.11 CDJ89988.1 - 1.9 9.2 5.5 2.9 8.6 5.5 1.5 1 1 0 1 1 1 0 Pal1 cell morphology protein Ribosomal_L28e PF01778.17 CDJ89989.1 - 1.2e-24 87.3 0.1 1.5e-24 86.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family MFS_1 PF07690.16 CDJ89990.1 - 7.2e-44 150.1 73.6 1.7e-35 122.6 40.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CDJ89990.1 - 2.8e-07 29.7 30.1 9.8e-06 24.7 3.2 3.6 2 1 0 3 3 3 2 MFS_1 like family UPF0060 PF02694.15 CDJ89990.1 - 0.29 11.4 9.8 0.23 11.7 1.6 3.4 2 1 1 3 3 3 0 Uncharacterised BCR, YnfA/UPF0060 family NNMT_PNMT_TEMT PF01234.17 CDJ89991.1 - 2.8e-76 256.1 0.0 3.2e-76 255.9 0.0 1.0 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_11 PF08241.12 CDJ89991.1 - 0.00012 22.6 0.0 0.0041 17.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ89991.1 - 0.016 15.9 0.0 6.6 7.5 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ89991.1 - 0.15 12.8 0.0 0.55 11.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain RGS PF00615.19 CDJ89993.1 - 4.8e-36 123.6 6.8 1.4e-18 67.3 0.7 3.0 3 0 0 3 3 3 2 Regulator of G protein signaling domain DUF4597 PF15366.6 CDJ89993.1 - 0.076 12.8 0.2 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) TFIIA_gamma_C PF02751.14 CDJ89994.1 - 9.6e-19 67.3 2.5 1.5e-18 66.7 2.5 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 CDJ89994.1 - 1.3e-18 66.7 0.1 2e-18 66.1 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain MarR_2 PF12802.7 CDJ89994.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 MarR family Serpin PF00079.20 CDJ89995.1 - 3.5e-08 33.2 0.0 1.1e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) GSK-3_bind PF05350.12 CDJ89995.1 - 0.037 13.3 0.4 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 Glycogen synthase kinase-3 binding PHD PF00628.29 CDJ89996.1 - 1e-09 38.1 20.1 1.9e-05 24.4 4.1 2.5 2 0 0 2 2 2 2 PHD-finger zf-AD PF07776.15 CDJ89996.1 - 0.67 10.2 0.1 0.67 10.2 0.1 3.7 3 1 1 4 4 4 0 Zinc-finger associated domain (zf-AD) Acetyltransf_1 PF00583.25 CDJ89997.1 - 1.3e-05 25.4 0.0 2.2e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDJ89997.1 - 0.001 19.5 0.0 0.0017 18.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CDJ89997.1 - 0.013 15.5 0.0 0.033 14.2 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDJ89997.1 - 0.044 13.7 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CDJ89997.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Dimer_Tnp_hAT PF05699.14 CDJ89997.1 - 0.14 12.0 0.3 0.55 10.1 0.3 2.0 1 1 1 2 2 2 0 hAT family C-terminal dimerisation region Toxin_TOLIP PF00087.21 CDJ89999.1 - 0.0079 16.4 7.6 0.0098 16.1 7.6 1.2 1 0 0 1 1 1 1 Snake toxin and toxin-like protein Bac_rhamnosid_C PF17390.2 CDJ89999.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase C-terminal domain RE_AlwI PF09491.10 CDJ90000.1 - 0.11 11.3 6.1 0.14 10.9 6.1 1.1 1 0 0 1 1 1 0 AlwI restriction endonuclease DUF1722 PF08349.11 CDJ90000.1 - 0.53 10.6 5.3 0.6 10.4 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1722) DUF4820 PF16091.5 CDJ90000.1 - 5.7 6.2 12.7 2.6 7.4 10.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4820) Peptidase_M2 PF01401.18 CDJ90000.1 - 9.8 4.7 8.4 0.71 8.4 2.9 1.7 1 1 1 2 2 2 0 Angiotensin-converting enzyme Tropomyosin_1 PF12718.7 CDJ90002.1 - 0.025 14.7 2.8 0.025 14.7 2.8 2.8 3 0 0 3 3 3 0 Tropomyosin like zf-RING_2 PF13639.6 CDJ90002.1 - 0.047 14.0 9.3 0.17 12.2 9.3 1.9 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 CDJ90002.1 - 0.14 12.0 3.1 0.47 10.4 3.3 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ90002.1 - 0.22 11.4 8.4 1.2 9.0 8.4 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.9 CDJ90002.1 - 0.22 11.6 0.1 0.22 11.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-RING_5 PF14634.6 CDJ90002.1 - 0.83 9.7 4.2 1.8 8.6 4.2 1.6 1 1 0 1 1 1 0 zinc-RING finger domain ZapB PF06005.12 CDJ90002.1 - 2.1 8.8 10.2 2.1 8.9 5.0 2.6 2 0 0 2 2 2 0 Cell division protein ZapB Peptidase_M10 PF00413.24 CDJ90006.1 - 5.5e-46 156.3 0.0 7.6e-46 155.8 0.0 1.2 1 0 0 1 1 1 1 Matrixin Astacin PF01400.24 CDJ90006.1 - 0.0072 16.0 0.0 0.71 9.5 0.0 2.2 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 CDJ90006.1 - 0.01 16.3 0.2 0.014 15.9 0.2 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 CDJ90006.1 - 0.017 15.1 0.0 0.042 13.8 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M54 Reprolysin_4 PF13583.6 CDJ90006.1 - 0.021 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 CDJ90006.1 - 0.058 12.0 0.0 0.086 11.4 0.0 1.1 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_5 PF13688.6 CDJ90006.1 - 0.073 13.2 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF4953 PF16313.5 CDJ90006.1 - 0.13 11.4 0.3 0.23 10.6 0.3 1.3 1 0 0 1 1 1 0 Met-zincin PEPCK_GTP PF00821.18 CDJ90007.1 - 5.3e-164 545.2 0.1 6.7e-164 544.9 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 CDJ90007.1 - 4.2e-93 311.0 0.0 5.5e-93 310.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain MRP-L28 PF09812.9 CDJ90008.1 - 1.9e-49 167.9 8.6 2.2e-49 167.7 8.6 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 GCN5L1 PF06320.13 CDJ90008.1 - 0.82 9.8 7.6 7.4 6.8 1.0 2.5 1 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) DUF1644 PF07800.12 CDJ90009.1 - 0.0057 16.7 0.4 1.4 9.0 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1644) Thyroglobulin_1 PF00086.18 CDJ90009.1 - 0.0091 15.6 1.5 0.038 13.7 1.5 2.1 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat zf-C2H2 PF00096.26 CDJ90009.1 - 0.1 13.1 28.4 0.8 10.3 0.5 5.6 5 0 0 5 5 5 0 Zinc finger, C2H2 type Spt4 PF06093.13 CDJ90010.1 - 5.5e-31 106.5 2.2 6.7e-31 106.2 2.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Pkinase_Tyr PF07714.17 CDJ90011.1 - 3.4e-34 118.3 0.0 4.9e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 CDJ90011.1 - 1.2e-27 96.3 4.4 4.3e-15 56.1 0.3 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ90011.1 - 1.4e-21 76.3 6.9 5.8e-09 36.1 1.2 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Pkinase PF00069.25 CDJ90011.1 - 1.7e-20 73.5 0.0 3.7e-20 72.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.6 CDJ90011.1 - 2e-20 72.9 1.1 2.3e-09 37.6 0.2 3.9 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 CDJ90011.1 - 1.2e-16 60.3 1.4 1.1e-05 25.6 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 CDJ90011.1 - 9.4e-14 50.2 0.6 0.0067 16.8 0.0 4.2 3 0 0 3 3 3 3 Ankyrin repeat IP_trans PF02121.18 CDJ90012.1 - 4.8e-112 373.5 0.0 5.4e-112 373.3 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Pkinase PF00069.25 CDJ90013.1 - 4.1e-36 124.7 4.3 2.4e-23 82.9 2.4 3.2 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ90013.1 - 4.1e-13 49.2 2.2 1.6e-11 44.0 0.0 2.9 2 1 0 3 3 3 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 CDJ90013.1 - 0.0087 15.1 0.1 0.013 14.5 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 CDJ90013.1 - 0.011 15.6 0.0 4.2 7.2 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ90013.1 - 0.03 13.1 2.3 0.022 13.6 0.4 1.7 1 1 0 1 1 1 0 Fungal protein kinase DDE_Tnp_1_6 PF13751.6 CDJ90013.1 - 0.047 13.9 0.1 3.5 7.9 0.0 2.6 2 0 0 2 2 2 0 Transposase DDE domain IL22 PF14565.6 CDJ90013.1 - 0.21 11.9 1.8 0.43 10.8 1.8 1.4 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor SR-25 PF10500.9 CDJ90013.1 - 0.89 9.1 15.3 0.12 12.0 3.2 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ribosomal_L6e PF01159.19 CDJ90013.1 - 2.5 8.7 8.6 0.09 13.3 1.7 2.0 2 0 0 2 2 2 0 Ribosomal protein L6e Haspin_kinase PF12330.8 CDJ90014.1 - 1.2e-58 198.8 0.0 2e-58 198.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CDJ90014.1 - 0.032 14.1 0.0 0.7 9.8 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.25 CDJ90014.1 - 0.096 12.0 0.0 8.7 5.6 0.0 2.4 2 0 0 2 2 2 0 Protein kinase domain DUF1639 PF07797.14 CDJ90014.1 - 0.19 11.8 0.6 20 5.3 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) An_peroxidase PF03098.15 CDJ90015.1 - 6.2e-144 480.5 0.0 8.3e-144 480.0 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase NAD_binding_6 PF08030.12 CDJ90015.1 - 2.1e-26 92.9 0.0 3.5e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CDJ90015.1 - 1.9e-16 60.1 0.0 5.2e-16 58.7 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 CDJ90015.1 - 1.1e-15 57.9 12.2 1.1e-15 57.9 12.2 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component EF-hand_7 PF13499.6 CDJ90015.1 - 2e-06 28.2 0.4 8.5e-05 22.9 0.1 2.9 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 CDJ90015.1 - 4.4e-05 23.1 0.1 2.6 8.2 0.0 4.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CDJ90015.1 - 0.017 14.6 0.0 6.3 6.6 0.0 3.4 3 0 0 3 3 3 0 EF hand DUF2600 PF10776.9 CDJ90015.1 - 0.084 11.7 0.0 0.29 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2600) An_peroxidase PF03098.15 CDJ90016.1 - 1.1e-48 166.2 0.0 3.2e-47 161.3 0.0 2.0 1 1 1 2 2 2 2 Animal haem peroxidase NAD_binding_6 PF08030.12 CDJ90017.1 - 2.1e-28 99.4 0.0 3.8e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CDJ90017.1 - 1.1e-17 64.1 0.0 2.6e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 CDJ90017.1 - 6.6e-14 52.1 6.6 1.3e-13 51.2 6.6 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component EF-hand_6 PF13405.6 CDJ90017.1 - 8.1e-06 25.4 3.5 0.0013 18.5 0.1 4.1 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 CDJ90017.1 - 2.3e-05 23.6 0.1 0.0084 15.6 0.0 3.5 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 CDJ90017.1 - 4.5e-05 23.2 0.2 0.0021 17.9 0.0 3.0 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 CDJ90017.1 - 0.0098 16.3 5.7 0.082 13.4 0.0 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ90017.1 - 0.056 13.0 0.7 0.17 11.4 0.0 2.3 2 0 0 2 2 2 0 EF hand Peptidase_M57 PF12388.8 CDJ90017.1 - 0.13 11.8 0.2 0.42 10.2 0.0 1.9 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase DUF4199 PF13858.6 CDJ90017.1 - 8 6.8 9.4 16 5.9 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Enkurin PF13864.6 CDJ90018.1 - 0.18 12.2 7.9 0.053 14.0 3.7 2.0 1 1 1 2 2 2 0 Calmodulin-binding DUF816 PF05674.12 CDJ90019.1 - 0.0043 17.0 0.3 0.0047 16.9 0.3 1.1 1 0 0 1 1 1 1 Baculovirus protein of unknown function (DUF816) Ldl_recept_a PF00057.18 CDJ90020.1 - 1.3e-11 44.5 6.4 1.1e-10 41.5 6.4 2.8 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Pkinase PF00069.25 CDJ90021.1 - 3.2e-65 220.1 0.0 5.5e-65 219.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ90021.1 - 7.7e-34 117.1 0.5 5.6e-33 114.3 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ90021.1 - 7.6e-05 21.8 0.2 0.00011 21.3 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CDJ90021.1 - 0.0013 17.6 0.1 0.0023 16.8 0.1 1.5 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDJ90021.1 - 0.012 15.0 0.0 0.041 13.2 0.0 1.9 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 CDJ90021.1 - 0.014 15.3 0.2 0.24 11.3 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family FTA2 PF13095.6 CDJ90021.1 - 0.09 12.4 0.1 0.5 10.0 0.0 2.0 1 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 K-cyclin_vir_C PF09080.10 CDJ90021.1 - 0.26 11.7 3.0 0.37 11.2 1.8 1.9 2 0 0 2 2 2 0 K cyclin, C terminal SKA2 PF16740.5 CDJ90021.1 - 2.8 7.7 7.9 0.14 12.0 1.7 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Coatomer_WDAD PF04053.14 CDJ90023.1 - 4.3e-162 540.2 0.1 4e-160 533.7 0.0 2.1 2 0 0 2 2 2 2 Coatomer WD associated region WD40 PF00400.32 CDJ90023.1 - 1.3e-41 139.8 8.5 2.2e-08 34.6 0.1 8.4 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ90023.1 - 1e-07 32.1 1.3 1.4 9.3 0.0 6.0 2 2 6 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDJ90023.1 - 0.0015 17.3 5.3 6.1 5.4 0.0 4.2 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Pkinase PF00069.25 CDJ90024.1 - 1.6e-43 149.0 0.0 2.2e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ90024.1 - 6.7e-20 71.5 0.0 1e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ90024.1 - 0.0024 17.2 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CDJ90024.1 - 0.011 14.6 1.5 1.5 7.5 0.0 2.4 3 0 0 3 3 3 0 Fungal protein kinase Atg14 PF10186.9 CDJ90027.1 - 0.077 12.1 2.4 0.1 11.7 2.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sulfate_transp PF00916.20 CDJ90028.1 - 4e-104 348.4 21.3 6e-104 347.8 21.3 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CDJ90028.1 - 2.9e-15 55.9 0.0 5.2e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain Corona_NS3b PF03053.14 CDJ90028.1 - 0.15 11.8 4.7 1.2 8.9 0.8 2.4 2 0 0 2 2 2 0 ORF3b coronavirus protein Calcyon PF06387.11 CDJ90028.1 - 0.72 9.8 0.0 0.72 9.8 0.0 2.7 3 0 0 3 3 3 0 D1 dopamine receptor-interacting protein (calcyon) zf-C4 PF00105.18 CDJ90029.1 - 1.7e-24 86.0 16.7 4.1e-24 84.8 16.7 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ90029.1 - 1.5e-12 47.5 1.5 6.3e-12 45.5 0.9 2.1 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor RasGEF PF00617.19 CDJ90030.1 - 1.2e-51 175.4 0.1 2.2e-51 174.6 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CDJ90030.1 - 6.8e-18 64.8 0.0 2.5e-17 63.0 0.0 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif RA PF00788.23 CDJ90030.1 - 1.3e-15 57.8 0.0 5.7e-15 55.7 0.0 2.1 1 1 1 2 2 2 1 Ras association (RalGDS/AF-6) domain Flp_C PF05202.12 CDJ90030.1 - 0.086 12.4 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Recombinase Flp protein ATP-gua_Ptrans PF00217.19 CDJ90032.1 - 3.2e-82 275.1 0.0 4.3e-82 274.7 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CDJ90032.1 - 3.1e-29 101.2 0.0 5.8e-29 100.3 0.0 1.5 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain DUF658 PF04936.12 CDJ90032.1 - 0.045 13.5 0.1 0.085 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF658) PhaP_Bmeg PF09602.10 CDJ90032.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Astacin PF01400.24 CDJ90033.1 - 5.3e-27 94.7 3.0 1.5e-19 70.4 0.2 2.3 1 1 1 2 2 2 2 Astacin (Peptidase family M12A) RVT_1 PF00078.27 CDJ90035.1 - 0.00016 21.3 0.0 0.00026 20.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) P_proprotein PF01483.20 CDJ90036.1 - 2.7e-28 97.8 0.2 4.9e-28 97.0 0.2 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain Choline_kinase PF01633.20 CDJ90039.1 - 4.3e-50 170.3 0.0 8.3e-50 169.3 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase UDPGT PF00201.18 CDJ90039.1 - 3.9e-40 138.1 0.0 4.1e-37 128.1 0.0 2.1 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ90039.1 - 6.7e-11 42.5 0.0 1.4e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain APH PF01636.23 CDJ90039.1 - 1.8e-08 34.6 0.0 5.7e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 CDJ90040.1 - 7.2e-21 74.7 0.0 1.1e-20 74.1 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ90040.1 - 1.6e-10 40.7 0.0 2.5e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ90040.1 - 0.00034 20.6 0.0 0.00085 19.3 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ90040.1 - 0.0036 16.7 0.1 0.0053 16.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDJ90040.1 - 0.045 12.5 0.0 0.045 12.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Perilipin PF03036.16 CDJ90041.1 - 0.00016 20.8 2.8 0.013 14.6 1.0 2.1 2 0 0 2 2 2 2 Perilipin family RasGAP_C PF03836.15 CDJ90041.1 - 0.00039 20.6 2.6 0.00039 20.6 2.6 1.5 2 0 0 2 2 1 1 RasGAP C-terminus Spc7 PF08317.11 CDJ90041.1 - 0.00047 19.1 8.9 0.00055 18.9 8.9 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF848 PF05852.11 CDJ90041.1 - 0.00052 20.2 4.1 0.00071 19.7 4.1 1.3 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) GAS PF13851.6 CDJ90041.1 - 0.0035 16.7 5.9 0.0035 16.7 5.9 1.7 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Filament PF00038.21 CDJ90041.1 - 0.0039 16.8 8.2 0.0039 16.8 7.1 1.3 1 1 0 1 1 1 1 Intermediate filament protein TelA PF05816.11 CDJ90041.1 - 0.0046 16.1 2.3 0.0055 15.8 2.3 1.1 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) DUF1664 PF07889.12 CDJ90041.1 - 0.0073 16.3 2.4 0.013 15.5 1.9 1.7 2 0 0 2 2 1 1 Protein of unknown function (DUF1664) DUF5082 PF16888.5 CDJ90041.1 - 0.0073 16.6 4.1 0.081 13.2 0.4 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF5082) YabA PF06156.13 CDJ90041.1 - 0.0074 16.9 3.5 0.012 16.3 2.8 1.8 1 1 0 1 1 1 1 Initiation control protein YabA Cnn_1N PF07989.11 CDJ90041.1 - 0.022 14.9 1.8 0.022 14.9 1.8 1.9 2 0 0 2 2 1 0 Centrosomin N-terminal motif 1 Rootletin PF15035.6 CDJ90041.1 - 0.03 14.3 6.6 0.041 13.9 6.6 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion RT_RNaseH PF17917.1 CDJ90041.1 - 0.03 14.6 0.1 0.044 14.1 0.1 1.5 1 1 0 1 1 1 0 RNase H-like domain found in reverse transcriptase BRE1 PF08647.11 CDJ90041.1 - 0.031 14.3 6.6 0.087 12.9 6.2 2.0 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase ApoLp-III PF07464.11 CDJ90041.1 - 0.033 14.3 4.4 0.098 12.7 4.4 1.8 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) TP_methylase PF00590.20 CDJ90041.1 - 0.037 14.0 0.3 0.063 13.2 0.3 1.3 1 1 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases AAA_13 PF13166.6 CDJ90041.1 - 0.039 12.6 5.5 0.047 12.3 5.5 1.1 1 0 0 1 1 1 0 AAA domain Dor1 PF04124.12 CDJ90041.1 - 0.047 12.4 4.2 0.057 12.1 4.2 1.1 1 0 0 1 1 1 0 Dor1-like family CdvA PF18822.1 CDJ90041.1 - 0.075 12.9 6.0 0.1 12.4 6.0 1.3 1 0 0 1 1 1 0 CdvA-like coiled-coil domain Exonuc_VII_L PF02601.15 CDJ90041.1 - 0.085 12.4 4.3 0.097 12.2 4.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prominin PF05478.11 CDJ90041.1 - 0.086 10.8 2.2 0.1 10.6 2.2 1.1 1 0 0 1 1 1 0 Prominin Syntaxin-6_N PF09177.11 CDJ90041.1 - 0.086 13.4 6.1 0.09 13.3 4.3 1.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal ERM PF00769.19 CDJ90041.1 - 0.091 12.6 9.4 0.11 12.3 9.4 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family COG5 PF10392.9 CDJ90041.1 - 0.099 12.8 3.1 0.17 12.0 3.1 1.6 1 1 0 1 1 1 0 Golgi transport complex subunit 5 JIP_LZII PF16471.5 CDJ90041.1 - 0.14 12.4 3.6 0.17 12.1 1.9 2.0 2 0 0 2 2 1 0 JNK-interacting protein leucine zipper II TMPIT PF07851.13 CDJ90041.1 - 0.18 11.0 4.4 0.18 11.0 3.6 1.4 1 1 0 1 1 1 0 TMPIT-like protein Cluap1 PF10234.9 CDJ90041.1 - 0.19 11.1 8.4 0.4 10.0 8.4 1.7 1 1 0 1 1 1 0 Clusterin-associated protein-1 Jnk-SapK_ap_N PF09744.9 CDJ90041.1 - 0.27 11.4 8.7 1.3 9.2 8.7 1.9 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Fib_alpha PF08702.10 CDJ90041.1 - 0.31 11.2 7.1 0.48 10.6 6.0 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF745 PF05335.13 CDJ90041.1 - 0.34 10.6 7.4 3.4 7.4 3.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) BLOC1_2 PF10046.9 CDJ90041.1 - 0.46 10.8 5.2 0.88 9.9 1.2 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.15 CDJ90041.1 - 0.59 9.9 6.5 0.47 10.3 3.1 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF4446 PF14584.6 CDJ90041.1 - 0.62 10.0 3.9 0.67 9.9 1.8 2.0 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) FUSC PF04632.12 CDJ90041.1 - 0.98 7.9 3.1 1.1 7.6 3.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-H PF05837.12 CDJ90041.1 - 1.1 9.7 9.1 1 9.8 7.7 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Csm1_N PF18504.1 CDJ90041.1 - 1.1 9.6 7.1 2.9 8.3 5.7 2.3 1 1 1 2 2 2 0 Csm1 N-terminal domain COG2 PF06148.11 CDJ90041.1 - 1.3 9.1 5.2 2 8.5 1.6 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cauli_AT PF03233.13 CDJ90041.1 - 1.3 8.9 4.9 5.5 6.9 3.5 2.0 1 1 1 2 2 2 0 Aphid transmission protein Snapin_Pallidin PF14712.6 CDJ90041.1 - 1.4 9.4 7.9 2.4 8.6 2.7 2.9 1 1 1 2 2 2 0 Snapin/Pallidin DivIVA PF05103.13 CDJ90041.1 - 1.6 8.8 9.5 1.1 9.3 3.9 2.4 1 1 1 2 2 2 0 DivIVA protein ZapB PF06005.12 CDJ90041.1 - 1.8 9.1 10.3 7.3 7.1 9.1 2.3 1 1 1 2 2 2 0 Cell division protein ZapB TMF_DNA_bd PF12329.8 CDJ90041.1 - 2.4 8.2 7.3 0.44 10.6 3.9 1.5 2 0 0 2 2 1 0 TATA element modulatory factor 1 DNA binding DUF16 PF01519.16 CDJ90041.1 - 2.5 8.6 6.1 15 6.1 6.1 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 SlyX PF04102.12 CDJ90041.1 - 2.8 8.6 6.1 64 4.3 0.2 2.9 1 1 2 3 3 3 0 SlyX UPF0242 PF06785.11 CDJ90041.1 - 3.6 7.7 7.8 11 6.1 7.3 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ras PF00071.22 CDJ90042.1 - 6.1e-58 195.0 0.0 7.1e-58 194.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ90042.1 - 3.8e-36 123.9 0.0 5.1e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ90042.1 - 3.3e-16 59.2 0.0 4.3e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ90042.1 - 3.1e-06 26.7 0.0 3.7e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDJ90042.1 - 4.6e-06 26.7 0.0 9.6e-06 25.7 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ90042.1 - 4.1e-05 23.2 0.2 0.00049 19.7 0.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 CDJ90042.1 - 0.00066 19.5 0.0 0.00088 19.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CDJ90042.1 - 0.00083 19.3 0.1 0.029 14.3 0.0 2.3 2 1 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CDJ90042.1 - 0.0045 17.4 0.0 0.0082 16.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain CENP-M PF11111.8 CDJ90042.1 - 0.0092 15.2 0.0 0.035 13.3 0.0 1.7 2 0 0 2 2 2 1 Centromere protein M (CENP-M) AAA_22 PF13401.6 CDJ90042.1 - 0.011 16.0 0.0 0.017 15.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 CDJ90042.1 - 0.012 15.4 0.1 0.16 11.7 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein SRPRB PF09439.10 CDJ90042.1 - 0.014 14.9 0.2 0.022 14.2 0.0 1.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Hpr_kinase_C PF07475.12 CDJ90042.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_29 PF13555.6 CDJ90042.1 - 0.016 14.9 0.2 0.039 13.7 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 CDJ90042.1 - 0.065 12.8 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 CDJ90042.1 - 0.089 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Septin NACHT PF05729.12 CDJ90042.1 - 0.095 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 CDJ90042.1 - 0.13 12.8 0.0 0.28 11.7 0.0 1.6 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 CDJ90042.1 - 0.19 11.5 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain IIGP PF05049.13 CDJ90042.1 - 0.2 10.7 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) RRM_1 PF00076.22 CDJ90043.1 - 5.6e-31 106.2 0.1 2.6e-14 52.8 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ90043.1 - 0.00017 21.4 0.0 3.5 7.5 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 CDJ90043.1 - 0.0003 20.9 0.0 0.019 15.1 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif Transformer PF06495.11 CDJ90043.1 - 0.07 13.2 28.2 0.11 12.6 28.2 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein RRM_9 PF18444.1 CDJ90043.1 - 0.14 12.0 0.1 0.63 9.9 0.0 2.1 3 0 0 3 3 3 0 RNA recognition motif CDC45 PF02724.14 CDJ90043.1 - 3.7 5.7 29.5 5.4 5.2 29.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 CDJ90043.1 - 5 5.9 11.6 6.9 5.4 11.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Cupin_8 PF13621.6 CDJ90045.1 - 2.2e-43 148.8 0.0 3.3e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CDJ90045.1 - 2.3e-07 30.6 0.0 3.8e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 CDJ90045.1 - 0.001 19.4 0.0 0.004 17.6 0.0 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 CDJ90045.1 - 0.11 12.3 0.0 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Cupin domain Cupin_1 PF00190.22 CDJ90045.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Cupin ANAPC_CDC26 PF10471.9 CDJ90046.1 - 0.67 10.8 13.7 10 7.0 12.2 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 SAPS PF04499.15 CDJ90046.1 - 4.8 5.9 13.6 5.6 5.6 13.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Rpr2 PF04032.16 CDJ90049.1 - 1e-08 35.4 3.5 2.4e-08 34.2 3.5 1.6 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Ribosomal_L24e PF01246.20 CDJ90049.1 - 0.16 12.2 2.7 0.45 10.8 2.7 1.9 1 1 0 1 1 1 0 Ribosomal protein L24e Dus PF01207.17 CDJ90050.1 - 5.7e-45 153.7 0.0 8.3e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 CDJ90050.1 - 8e-07 28.7 5.5 1.1e-05 25.1 0.0 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH PF00642.24 CDJ90050.1 - 0.012 15.5 5.7 1.1 9.3 2.0 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RE_NgoFVII PF09565.10 CDJ90050.1 - 0.21 10.8 0.1 0.31 10.3 0.1 1.2 1 0 0 1 1 1 0 NgoFVII restriction endonuclease Torus PF16131.5 CDJ90050.1 - 1.3 9.8 4.5 1.4 9.7 0.2 2.3 1 1 1 2 2 2 0 Torus domain BORCS6 PF10157.9 CDJ90051.1 - 1.8e-30 106.2 0.3 3.6e-30 105.2 0.3 1.5 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 Peptidase_M1 PF01433.20 CDJ90051.1 - 6.7e-07 29.1 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain HEAT_2 PF13646.6 CDJ90051.1 - 9e-06 26.0 0.0 0.041 14.3 0.0 2.6 2 0 0 2 2 2 2 HEAT repeats Peptidase_M1_N PF17900.1 CDJ90051.1 - 0.0011 19.1 0.0 0.0023 18.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain zf-H2C2_2 PF13465.6 CDJ90052.1 - 5.3e-15 55.1 28.5 9.1e-05 22.7 0.4 4.8 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 CDJ90052.1 - 1.5e-14 53.5 30.1 1.3e-06 28.5 2.0 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ90052.1 - 2e-14 53.1 26.5 0.001 19.7 1.2 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ90052.1 - 9e-09 35.4 10.2 0.018 15.3 0.4 3.5 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDJ90052.1 - 8.7e-06 26.0 20.8 0.0059 17.0 3.1 4.3 5 0 0 5 5 4 2 Zinc-finger of C2H2 type zf_UBZ PF18439.1 CDJ90052.1 - 0.00014 21.4 8.4 0.91 9.2 0.0 4.5 4 0 0 4 4 4 1 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 CDJ90052.1 - 0.00042 20.0 22.4 0.083 12.7 2.1 4.1 4 0 0 4 4 4 3 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 CDJ90052.1 - 0.00069 20.3 5.2 0.37 11.6 0.2 2.2 1 1 1 2 2 2 2 zinc-ribbon family zf-C2H2_6 PF13912.6 CDJ90052.1 - 0.00074 19.5 30.9 0.0087 16.0 0.1 5.3 5 1 0 5 5 5 2 C2H2-type zinc finger Elf1 PF05129.13 CDJ90052.1 - 0.0014 18.7 5.1 0.017 15.1 0.5 2.4 1 1 1 2 2 2 1 Transcription elongation factor Elf1 like zf-LYAR PF08790.11 CDJ90052.1 - 0.003 17.4 6.3 4.3 7.3 0.1 3.4 3 0 0 3 3 3 1 LYAR-type C2HC zinc finger zf-C2H2_8 PF15909.5 CDJ90052.1 - 0.0043 17.3 4.2 0.0043 17.3 4.2 2.2 1 1 0 2 2 2 1 C2H2-type zinc ribbon zf-ribbon_3 PF13248.6 CDJ90052.1 - 0.0066 15.8 5.8 3.2 7.3 0.7 3.4 3 0 0 3 3 3 1 zinc-ribbon domain ADK_lid PF05191.14 CDJ90052.1 - 0.0068 16.4 4.5 0.079 13.0 0.5 3.1 2 2 1 3 3 3 1 Adenylate kinase, active site lid zinc_ribbon_4 PF13717.6 CDJ90052.1 - 0.0079 16.1 7.3 2.3 8.2 0.0 3.8 4 0 0 4 4 4 1 zinc-ribbon domain FOXP-CC PF16159.5 CDJ90052.1 - 0.0085 16.7 3.2 0.016 15.9 1.2 2.1 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-C2H2_3rep PF18868.1 CDJ90052.1 - 0.011 16.4 7.6 0.35 11.5 2.6 2.8 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats CpXC PF14353.6 CDJ90052.1 - 0.012 15.7 8.4 0.17 12.0 0.1 3.4 1 1 3 4 4 4 0 CpXC protein zf-C2H2_2 PF12756.7 CDJ90052.1 - 0.016 15.5 14.0 0.37 11.2 6.0 3.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 CDJ90052.1 - 0.035 14.2 9.7 0.059 13.5 1.0 3.2 2 2 1 3 3 3 0 Zinc ribbon domain LIM PF00412.22 CDJ90052.1 - 0.037 14.2 10.4 1.1 9.6 0.8 3.1 1 1 2 3 3 3 0 LIM domain IBR PF01485.21 CDJ90052.1 - 0.037 14.2 13.3 1.5e+02 2.7 13.3 2.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zinc-ribbons_6 PF07191.12 CDJ90052.1 - 0.05 13.6 8.6 0.23 11.4 1.8 2.9 1 1 1 2 2 2 0 zinc-ribbons zf-DNA_Pol PF08996.10 CDJ90052.1 - 0.058 13.1 7.7 0.21 11.3 2.4 2.2 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger ARS2 PF04959.13 CDJ90052.1 - 0.14 12.5 1.5 4.1 7.7 0.1 2.1 2 0 0 2 2 2 0 Arsenite-resistance protein 2 FdhE PF04216.12 CDJ90052.1 - 0.24 11.3 5.3 0.15 11.9 0.6 2.0 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation zf-HIT PF04438.16 CDJ90052.1 - 0.38 10.7 9.5 17 5.4 0.1 3.5 3 0 0 3 3 3 0 HIT zinc finger PyrI_C PF02748.15 CDJ90052.1 - 0.47 10.4 5.1 2.3 8.2 0.5 2.7 2 1 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc_ribbon_9 PF14369.6 CDJ90052.1 - 1.5 9.2 8.5 10 6.4 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon Nudix_N_2 PF14803.6 CDJ90052.1 - 1.5 8.8 11.4 18 5.4 0.2 3.8 3 1 0 3 3 3 0 Nudix N-terminal zf-AN1 PF01428.16 CDJ90052.1 - 2 8.6 19.9 1.8 8.8 3.0 4.4 3 2 0 3 3 3 0 AN1-like Zinc finger DUF629 PF04780.12 CDJ90052.1 - 2.6 6.5 11.5 6 5.3 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF629) Rubredoxin_2 PF18073.1 CDJ90052.1 - 2.7 7.8 10.5 14 5.5 0.4 3.4 3 0 0 3 3 3 0 Rubredoxin metal binding domain FYDLN_acid PF09538.10 CDJ90052.1 - 4.2 8.1 6.8 25 5.6 0.9 3.4 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-H2C2_5 PF13909.6 CDJ90052.1 - 4.2 7.2 30.8 0.17 11.7 8.3 4.3 4 1 0 4 4 4 0 C2H2-type zinc-finger domain Peptidase_M24 PF00557.24 CDJ90053.1 - 5.6e-51 173.2 0.2 9e-51 172.5 0.2 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 CDJ90053.1 - 1.1e-18 67.2 8.3 2.5e-18 66.1 8.3 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 CDJ90053.1 - 5.6e-05 23.1 4.6 0.00016 21.7 4.6 1.8 1 0 0 1 1 1 1 MYND finger 3HCDH PF00725.22 CDJ90053.1 - 0.023 15.3 0.0 7.1 7.3 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ATP-cone PF03477.16 CDJ90053.1 - 0.046 14.3 0.0 17 6.1 0.0 2.3 2 0 0 2 2 2 0 ATP cone domain 7TM_GPCR_Sra PF02117.16 CDJ90054.1 - 8.2e-19 67.6 15.3 9.9e-19 67.3 15.3 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sra 7TM_GPCR_Srab PF10292.9 CDJ90054.1 - 4.9e-18 65.1 13.5 6.7e-18 64.7 13.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Srb PF02175.16 CDJ90054.1 - 2.1e-07 31.0 15.4 2.1e-07 31.0 15.4 1.4 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srb Sre PF03125.18 CDJ90054.1 - 2.6e-05 23.5 17.4 0.007 15.6 0.8 2.3 2 0 0 2 2 2 2 C. elegans Sre G protein-coupled chemoreceptor SH PF01445.17 CDJ90054.1 - 0.33 10.9 0.2 0.33 10.9 0.2 2.5 3 0 0 3 3 3 0 Viral small hydrophobic protein UL45 PF05473.12 CDJ90055.1 - 0.7 9.5 6.4 1.2 8.8 6.4 1.3 1 1 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like 6PF2K PF01591.18 CDJ90056.1 - 1e-92 309.5 0.6 1.4e-92 309.0 0.6 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CDJ90056.1 - 3.5e-43 147.6 0.0 5.5e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CDJ90056.1 - 1.3e-08 35.1 0.0 2.9e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CDJ90056.1 - 0.019 14.5 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 CDJ90056.1 - 0.033 13.5 0.0 1.2 8.4 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin AAA_17 PF13207.6 CDJ90056.1 - 0.033 14.6 0.0 0.076 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.7 CDJ90057.1 - 1.1e-43 147.8 9.1 8.6e-17 61.5 0.9 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ90057.1 - 8.3e-39 130.4 12.0 4.4e-09 36.4 0.1 7.0 6 1 1 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 CDJ90057.1 - 5.8e-35 119.2 9.7 5.7e-10 39.5 0.2 6.2 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ90057.1 - 2.4e-33 110.4 2.4 1e-05 25.5 0.0 7.2 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.6 CDJ90057.1 - 3.2e-31 107.0 10.9 4.8e-09 36.3 0.1 6.3 3 3 3 6 6 6 6 Ankyrin repeats (many copies) PK_C PF02887.16 CDJ90057.1 - 0.015 15.5 0.0 0.054 13.7 0.0 1.9 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain Imm_superinfect PF14373.6 CDJ90057.1 - 0.056 13.4 0.0 7 6.7 0.0 3.3 3 0 0 3 3 3 0 Superinfection immunity protein MFS_1 PF07690.16 CDJ90058.1 - 8.5e-07 28.2 12.4 2.6e-06 26.6 12.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily COesterase PF00135.28 CDJ90059.1 - 1.3e-19 70.5 0.0 1.4e-19 70.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family SNF2_N PF00176.23 CDJ90060.1 - 6.4e-79 265.2 1.2 1.2e-78 264.3 1.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HAND PF09110.11 CDJ90060.1 - 3e-27 95.6 10.1 4.7e-27 94.9 5.0 3.7 4 0 0 4 4 4 2 HAND Helicase_C PF00271.31 CDJ90060.1 - 1.7e-20 73.4 0.0 1.1e-19 70.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ90060.1 - 6.6e-12 45.8 1.3 1.9e-11 44.3 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ90060.1 - 1.9e-08 34.3 0.0 4.3e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 CDJ90060.1 - 1.1e-07 31.3 0.7 8.1e-07 28.5 0.0 2.6 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 CDJ90060.1 - 9.4e-05 22.2 0.1 0.00029 20.6 0.1 1.8 1 1 0 1 1 1 1 SWI2/SNF2 ATPase DUF896 PF05979.12 CDJ90060.1 - 0.085 12.7 1.3 14 5.7 0.1 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Pcc1 PF09341.10 CDJ90061.1 - 1.2e-12 47.8 1.0 1.5e-12 47.5 1.0 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 KAsynt_C_assoc PF16197.5 CDJ90061.1 - 0.11 12.9 0.0 0.16 12.4 0.0 1.3 1 1 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension Lsr2 PF11774.8 CDJ90061.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Lsr2 LppA PF16708.5 CDJ90062.1 - 0.04 13.9 2.1 0.12 12.2 1.3 2.3 2 0 0 2 2 2 0 Lipoprotein confined to pathogenic Mycobacterium Cytochrome-c551 PF10643.9 CDJ90062.1 - 0.39 10.3 1.0 8.5 5.9 0.1 2.2 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 CorA PF01544.18 CDJ90062.1 - 9 5.5 21.5 0.42 9.9 0.2 3.4 2 1 0 3 3 3 0 CorA-like Mg2+ transporter protein CHDCT2 PF08074.11 CDJ90063.1 - 0.14 12.4 0.1 0.16 12.1 0.1 1.1 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Cyt-b5 PF00173.28 CDJ90064.1 - 1.7e-11 44.1 0.2 3e-11 43.3 0.2 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CBFD_NFYB_HMF PF00808.23 CDJ90065.1 - 7.1e-13 48.6 0.0 1.5e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDJ90065.1 - 1.6e-06 28.5 1.0 5.3e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 CDJ90065.1 - 0.017 15.3 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) UPF0542 PF15086.6 CDJ90065.1 - 0.18 11.8 0.7 0.32 10.9 0.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 AAA_12 PF13087.6 CDJ90066.1 - 2.4e-36 125.2 0.0 3.7e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ90066.1 - 9e-07 28.9 0.0 0.00022 21.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CDJ90066.1 - 6.7e-06 25.9 0.0 0.088 12.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 CDJ90066.1 - 0.00042 20.1 0.1 0.17 11.6 0.1 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 CDJ90066.1 - 0.0019 18.5 0.1 0.044 14.1 0.1 2.6 2 1 0 2 2 2 1 AAA domain US2 PF02476.15 CDJ90066.1 - 0.0098 16.6 0.0 0.023 15.4 0.0 1.6 1 0 0 1 1 1 1 US2 family PhoH PF02562.16 CDJ90066.1 - 0.32 10.4 1.2 4.5 6.7 0.2 2.6 2 1 1 3 3 3 0 PhoH-like protein AAA_12 PF13087.6 CDJ90067.1 - 1.3e-36 126.1 0.0 1.9e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ90067.1 - 2.4e-06 27.5 0.0 0.00096 19.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CDJ90067.1 - 2.6e-05 24.0 0.0 0.25 11.0 0.0 2.9 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 CDJ90067.1 - 6.6e-05 22.7 0.0 0.021 14.6 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 CDJ90067.1 - 0.0014 19.0 0.1 0.026 14.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 CDJ90067.1 - 0.03 14.1 0.0 0.069 13.0 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.14 CDJ90067.1 - 0.072 12.9 0.1 3.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Helicase DUF2075 PF09848.9 CDJ90067.1 - 0.15 11.3 0.0 2.4 7.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TsaE PF02367.17 CDJ90067.1 - 0.18 11.8 0.0 0.56 10.2 0.0 1.9 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Kinesin PF00225.23 CDJ90068.1 - 5.2e-107 357.6 0.0 5.2e-107 357.6 0.0 2.4 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ90068.1 - 9.3e-22 77.6 1.4 2.5e-21 76.2 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding TPR_MLP1_2 PF07926.12 CDJ90068.1 - 0.011 15.8 1.5 0.011 15.8 1.5 6.9 5 1 3 8 8 8 0 TPR/MLP1/MLP2-like protein DivIC PF04977.15 CDJ90068.1 - 0.072 12.9 0.3 0.072 12.9 0.3 9.1 7 2 3 10 10 10 0 Septum formation initiator Lectin_C_term PF18022.1 CDJ90068.1 - 0.11 13.0 0.8 0.33 11.4 0.1 2.2 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin C-terminal domain His_Phos_1 PF00300.22 CDJ90069.1 - 0.0092 15.7 0.0 0.012 15.3 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HC2 PF07382.11 CDJ90072.1 - 0.00096 19.3 0.2 0.014 15.5 0.0 1.9 1 1 1 2 2 2 1 Histone H1-like nucleoprotein HC2 CX9C PF16860.5 CDJ90072.1 - 0.067 13.2 26.6 0.44 10.6 3.4 5.6 5 1 2 7 7 7 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, TRF PF08558.10 CDJ90072.1 - 1.1 8.8 3.4 2.7 7.5 0.3 2.3 2 1 0 2 2 2 0 Telomere repeat binding factor (TRF) GCK PF07802.11 CDJ90072.1 - 1.7 9.1 44.2 2.2 8.7 1.7 6.6 1 1 5 6 6 6 0 GCK domain V-ATPase_H_C PF11698.8 CDJ90072.1 - 5.2 7.2 8.9 43 4.3 4.5 3.0 1 1 1 2 2 2 0 V-ATPase subunit H HEPN_RiboL-PSP PF18735.1 CDJ90074.1 - 0.66 9.9 4.7 0.76 9.7 2.6 2.2 2 1 0 2 2 2 0 RiboL-PSP-HEPN PHD PF00628.29 CDJ90075.1 - 0.00016 21.5 5.6 0.00016 21.5 5.6 2.4 1 1 1 2 2 2 1 PHD-finger zf-RING_9 PF13901.6 CDJ90075.1 - 0.073 13.0 5.1 0.1 12.5 5.1 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon LMBR1 PF04791.16 CDJ90077.1 - 1.9e-144 482.4 17.7 1.9e-144 482.4 17.7 1.4 2 0 0 2 2 2 1 LMBR1-like membrane protein Tim17 PF02466.19 CDJ90077.1 - 9e-25 87.2 4.5 1.7e-24 86.3 4.5 1.5 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Oleosin PF01277.17 CDJ90077.1 - 0.045 13.5 1.6 0.14 11.9 1.6 1.9 1 0 0 1 1 1 0 Oleosin ATP-synt_F6 PF05511.11 CDJ90078.1 - 3.5e-08 33.7 0.0 6.3e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 ATP_sub_h PF10775.9 CDJ90078.1 - 0.00022 21.1 0.3 0.00078 19.4 0.1 2.1 2 0 0 2 2 2 1 ATP synthase complex subunit h RT_RNaseH_2 PF17919.1 CDJ90079.1 - 1.2e-35 121.5 0.2 8.6e-35 118.8 0.1 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ90079.1 - 3.6e-33 114.0 0.0 5.3e-32 110.2 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ90079.1 - 5.2e-22 78.4 0.0 1.2e-21 77.2 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ90079.1 - 9.1e-19 67.3 0.1 3.1e-18 65.6 0.1 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CDJ90079.1 - 0.00013 22.1 0.1 0.00034 20.8 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 CDJ90079.1 - 0.00018 22.0 0.0 0.00068 20.2 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ90079.1 - 0.0052 17.3 0.0 0.022 15.3 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ90079.1 - 0.051 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Mcp5_PH PF12814.7 CDJ90079.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Zona_pellucida PF00100.23 CDJ90080.1 - 1.5e-14 54.4 7.7 1.8e-14 54.2 7.7 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.23 CDJ90081.1 - 1e-10 41.9 2.3 1.3e-10 41.5 2.3 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Forkhead PF00250.18 CDJ90082.1 - 9.7e-37 125.1 0.0 1.6e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain Lin-8 PF03353.15 CDJ90082.1 - 0.81 9.2 4.0 15 5.0 3.1 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Ground-like PF04155.18 CDJ90083.1 - 8e-14 52.1 0.1 1.1e-13 51.6 0.1 1.2 1 0 0 1 1 1 1 Ground-like domain Toxin_YhaV PF11663.8 CDJ90083.1 - 0.1 12.7 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Toxin with endonuclease activity, of toxin-antitoxin system 7TM_GPCR_Srab PF10292.9 CDJ90084.1 - 5.1e-11 42.1 19.3 6.4e-11 41.7 19.3 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor Sre PF03125.18 CDJ90084.1 - 1.7e-06 27.5 26.1 9.2e-05 21.7 26.0 2.9 1 1 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor 7tm_1 PF00001.21 CDJ90084.1 - 0.21 10.9 16.3 0.28 10.4 16.3 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Pkinase PF00069.25 CDJ90086.1 - 1.2e-12 47.8 0.0 2.1e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain PQQ_2 PF13360.6 CDJ90086.1 - 1.8e-10 40.8 0.0 3.6e-06 26.7 0.1 3.1 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.21 CDJ90086.1 - 3.8e-09 36.0 0.2 0.01 15.8 0.1 3.8 4 0 0 4 4 4 3 PQQ enzyme repeat Pkinase_Tyr PF07714.17 CDJ90086.1 - 2.9e-06 26.8 0.0 6.6e-06 25.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PQQ_3 PF13570.6 CDJ90086.1 - 0.0007 20.0 0.1 0.036 14.6 0.0 3.7 4 1 0 4 4 4 1 PQQ-like domain 7tm_1 PF00001.21 CDJ90087.1 - 6e-09 35.6 21.4 6.8e-09 35.4 17.4 2.4 1 1 2 3 3 3 2 7 transmembrane receptor (rhodopsin family) AC_N PF16214.5 CDJ90087.1 - 0.099 11.8 7.2 0.16 11.1 7.2 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Pkinase PF00069.25 CDJ90088.1 - 1.9e-75 253.7 0.0 2.1e-75 253.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ90088.1 - 2.1e-35 122.2 0.0 2.7e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ90088.1 - 8.8e-05 21.6 0.0 0.00045 19.3 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CDJ90088.1 - 0.00023 21.2 0.0 0.00031 20.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CDJ90088.1 - 0.00071 19.0 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDJ90088.1 - 0.055 12.8 0.1 0.13 11.6 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CDJ90088.1 - 0.2 10.7 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 2-oxoacid_dh PF00198.23 CDJ90089.1 - 2e-48 164.9 0.1 2.6e-48 164.5 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Thioredoxin_8 PF13905.6 CDJ90089.1 - 9.4e-23 80.4 0.0 1.9e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like E3_binding PF02817.17 CDJ90089.1 - 3.8e-07 30.3 0.0 1.4e-06 28.5 0.0 2.1 2 0 0 2 2 2 1 e3 binding domain AhpC-TSA PF00578.21 CDJ90089.1 - 3.9e-07 30.0 0.0 1.1e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin PF00085.20 CDJ90089.1 - 9.8e-07 28.7 0.0 0.00011 22.1 0.0 2.6 1 1 1 2 2 2 1 Thioredoxin Redoxin PF08534.10 CDJ90089.1 - 4.8e-05 23.1 0.0 0.00015 21.5 0.0 1.8 2 0 0 2 2 2 1 Redoxin Thioredoxin_2 PF13098.6 CDJ90089.1 - 0.0037 17.7 0.0 0.015 15.7 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain TraF PF13728.6 CDJ90089.1 - 0.094 12.5 0.3 0.98 9.2 0.0 2.6 2 1 0 2 2 2 0 F plasmid transfer operon protein RP-C_C PF11800.8 CDJ90090.1 - 0.054 13.6 4.6 0.08 13.0 4.6 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Presenilin PF01080.17 CDJ90090.1 - 0.12 11.1 0.9 0.15 10.8 0.9 1.2 1 0 0 1 1 1 0 Presenilin SRP-alpha_N PF04086.13 CDJ90090.1 - 0.38 10.6 12.0 0.54 10.1 12.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DDHD PF02862.17 CDJ90090.1 - 0.53 10.4 5.2 0.66 10.1 5.2 1.3 1 1 0 1 1 1 0 DDHD domain MAJIN PF15077.6 CDJ90090.1 - 2 8.1 5.1 3.1 7.5 5.1 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein IHABP4_N PF16174.5 CDJ90090.1 - 5.4 7.6 12.8 8.8 6.9 12.8 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Vfa1 PF08432.10 CDJ90090.1 - 5.4 7.3 12.0 8.2 6.7 12.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 L51_S25_CI-B8 PF05047.16 CDJ90091.1 - 2.8e-10 40.0 0.0 6e-10 38.9 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Zot PF05707.12 CDJ90091.1 - 0.023 14.3 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) Trypan_PARP PF05887.11 CDJ90092.1 - 0.003 17.5 16.2 0.003 17.5 16.2 2.0 1 1 1 2 2 2 1 Procyclic acidic repetitive protein (PARP) Apt1 PF10351.9 CDJ90092.1 - 0.0088 15.0 1.7 0.0096 14.8 1.7 1.0 1 0 0 1 1 1 1 Golgi-body localisation protein domain Zip PF02535.22 CDJ90092.1 - 0.19 10.9 0.2 0.19 10.9 0.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter GAGA_bind PF06217.12 CDJ90092.1 - 0.42 10.9 9.1 0.57 10.4 9.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DEC-1_N PF04625.13 CDJ90092.1 - 1.6 7.7 21.4 1.2 8.0 18.4 2.0 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Neur_chan_memb PF02932.16 CDJ90092.1 - 2.1 8.3 3.9 2.4 8.2 3.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3807 PF12720.7 CDJ90092.1 - 3.5 7.9 12.0 4.7 7.5 12.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) SRP-alpha_N PF04086.13 CDJ90092.1 - 4.8 7.0 13.9 6.2 6.6 13.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SelP_N PF04592.14 CDJ90092.1 - 7.1 5.9 10.3 9.6 5.5 10.3 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RR_TM4-6 PF06459.12 CDJ90092.1 - 7.7 6.2 11.5 10 5.9 11.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpb1_1 PF04997.12 CDJ90094.1 - 1.4e-85 287.4 0.1 2e-85 286.9 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 CDJ90094.1 - 8.7e-75 250.5 0.1 1.6e-74 249.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CDJ90094.1 - 1.3e-18 67.4 0.0 2.9e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 BUD22 PF09073.10 CDJ90095.1 - 1.1e-09 38.1 51.9 1.7e-06 27.7 10.7 3.6 2 1 1 3 3 3 2 BUD22 IZUMO PF15005.6 CDJ90095.1 - 0.4 11.2 3.1 14 6.2 0.2 2.5 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Pterin_4a PF01329.19 CDJ90096.1 - 5.6e-32 109.8 0.1 6.6e-32 109.5 0.1 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase DUF1018 PF06252.12 CDJ90096.1 - 0.14 13.2 0.0 0.17 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) RNase_Zc3h12a PF11977.8 CDJ90097.1 - 5.5e-57 191.9 0.0 7.6e-57 191.5 0.0 1.2 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain UBA_6 PF18039.1 CDJ90097.1 - 2.1e-11 43.5 0.0 4.3e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain zf-CCCH_4 PF18044.1 CDJ90097.1 - 1.8e-05 24.4 3.6 4.3e-05 23.2 3.6 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 CDJ90097.1 - 0.0043 16.9 2.7 0.0099 15.8 2.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Regnase_1_C PF18561.1 CDJ90097.1 - 0.0053 16.5 0.1 0.015 15.1 0.0 1.7 2 0 0 2 2 2 1 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain PRORP PF16953.5 CDJ90097.1 - 0.035 13.6 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein-only RNase P zf-CCCH_2 PF14608.6 CDJ90097.1 - 0.37 11.3 3.8 1 9.9 3.8 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 CDJ90097.1 - 1.5 9.0 4.8 3.5 7.8 4.8 1.7 1 0 0 1 1 1 0 Zinc finger domain AFG1_ATPase PF03969.16 CDJ90098.1 - 1.5e-104 349.8 0.3 1.5e-101 339.9 0.1 2.0 1 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 CDJ90098.1 - 9.4e-05 22.9 0.3 0.042 14.2 0.0 3.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 CDJ90098.1 - 0.0016 18.2 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.6 CDJ90098.1 - 0.0039 17.2 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 CDJ90098.1 - 0.023 14.5 0.3 2.4 7.9 0.1 3.1 2 1 0 2 2 2 0 Bacterial dnaA protein AAA PF00004.29 CDJ90098.1 - 0.035 14.5 0.4 0.81 10.1 0.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RINGv PF12906.7 CDJ90099.1 - 3.7e-12 46.2 7.5 7.2e-12 45.2 7.5 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 CDJ90099.1 - 0.25 11.7 7.8 0.57 10.6 7.8 1.6 1 0 0 1 1 1 0 Ring finger domain Zf_RING PF16744.5 CDJ90099.1 - 0.59 10.3 5.8 1.4 9.1 5.8 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger zf-rbx1 PF12678.7 CDJ90099.1 - 5.3 7.4 7.4 45 4.4 7.4 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger domain XRN_M PF17846.1 CDJ90100.1 - 8.5e-154 512.7 0.0 1.5e-153 511.9 0.0 1.4 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 CDJ90100.1 - 1.1e-100 336.0 0.2 2.9e-100 334.7 0.0 1.7 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus CLIP1_ZNF PF16641.5 CDJ90100.1 - 0.063 13.2 0.6 0.11 12.4 0.6 1.4 1 0 0 1 1 1 0 CLIP1 zinc knuckle PTR2 PF00854.21 CDJ90101.1 - 8.4e-110 367.3 8.6 1.2e-97 327.2 5.2 2.2 2 0 0 2 2 2 2 POT family Lysis_col PF02402.16 CDJ90101.1 - 0.09 12.5 0.3 0.24 11.1 0.3 1.7 1 0 0 1 1 1 0 Lysis protein fn3 PF00041.21 CDJ90102.1 - 1.4e-23 83.1 5.4 9.7e-13 48.3 0.1 2.5 2 0 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CDJ90102.1 - 2.1e-11 44.2 3.9 3.1e-05 24.5 2.0 2.8 2 1 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 CDJ90102.1 - 0.00017 21.9 0.1 0.51 10.7 0.0 2.4 2 0 0 2 2 2 2 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 CDJ90102.1 - 0.0013 19.0 0.0 0.49 10.8 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2369) DUF4998 PF16389.5 CDJ90102.1 - 0.027 14.0 0.0 3.8 7.0 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function Arylsulfotran_N PF17425.2 CDJ90102.1 - 0.095 12.7 0.0 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 Arylsulfotransferase Ig-like domain Phosphorylase PF00343.20 CDJ90103.1 - 0 1146.7 0.0 0 1146.4 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase DPCD PF14913.6 CDJ90103.1 - 0.039 13.3 0.1 0.09 12.1 0.1 1.5 1 0 0 1 1 1 0 DPCD protein family MAF_flag10 PF01973.18 CDJ90103.1 - 0.17 11.6 0.1 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF115 TRAPPC9-Trs120 PF08626.11 CDJ90104.1 - 3.1e-20 71.3 0.0 4.9e-09 34.2 0.0 4.0 3 1 0 3 3 3 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit A2M_BRD PF07703.14 CDJ90107.1 - 1.8e-26 93.1 0.8 1.8e-26 93.1 0.8 3.4 3 1 0 3 3 3 1 Alpha-2-macroglobulin bait region domain MG3 PF17791.1 CDJ90107.1 - 6.4e-23 80.8 0.1 2e-22 79.2 0.1 1.9 1 0 0 1 1 1 1 Macroglobulin domain MG3 MG2 PF01835.19 CDJ90107.1 - 4.5e-20 71.9 0.3 3.9e-18 65.7 0.1 3.2 3 0 0 3 3 3 1 MG2 domain MG4 PF17789.1 CDJ90107.1 - 5.3e-07 29.7 8.9 0.00069 19.7 0.1 4.3 3 1 0 3 3 3 2 Macroglobulin domain MG4 DUF3859 PF12975.7 CDJ90107.1 - 0.0036 17.3 0.2 0.14 12.1 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3859) FlgD_ig PF13860.6 CDJ90107.1 - 0.015 15.2 0.3 1.9 8.4 0.0 3.0 2 0 0 2 2 2 0 FlgD Ig-like domain DUF559 PF04480.12 CDJ90107.1 - 0.047 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF559) UNC-93 PF05978.16 CDJ90108.1 - 4e-07 29.9 7.2 4e-07 29.9 7.2 2.8 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 CDJ90108.1 - 1.2e-06 27.7 38.5 2.3e-06 26.8 18.8 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily STN1_2 PF09170.10 CDJ90108.1 - 0.015 15.5 0.2 0.029 14.6 0.2 1.3 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Orbi_VP6 PF01516.16 CDJ90108.1 - 0.039 13.5 0.2 0.062 12.8 0.2 1.2 1 0 0 1 1 1 0 Orbivirus helicase VP6 DLH PF01738.18 CDJ90109.1 - 1.6e-44 152.1 0.1 1.8e-44 151.9 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.12 CDJ90109.1 - 2.7e-08 32.9 0.0 4.7e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 CDJ90109.1 - 3.3e-08 33.7 0.2 6.1e-05 23.0 0.0 2.6 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 CDJ90109.1 - 5.6e-05 22.7 0.4 0.00055 19.5 0.0 2.0 1 1 0 2 2 2 1 Prolyl oligopeptidase family DUF1100 PF06500.11 CDJ90109.1 - 0.0026 16.6 0.0 0.0037 16.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Chlorophyllase2 PF12740.7 CDJ90109.1 - 0.15 10.9 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme Pkinase PF00069.25 CDJ90110.1 - 3e-46 157.9 0.0 3.4e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ90110.1 - 1.7e-17 63.6 0.0 2.3e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ90110.1 - 0.00075 18.9 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Zona_pellucida PF00100.23 CDJ90112.1 - 2.4e-12 47.2 5.1 3.6e-12 46.6 5.1 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Pkinase PF00069.25 CDJ90113.1 - 6e-21 75.0 0.7 6.6e-21 74.9 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ90113.1 - 5.9e-13 48.7 0.0 8.3e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ90113.1 - 0.00062 19.8 0.0 0.0019 18.2 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ90113.1 - 0.019 13.7 0.5 0.029 13.1 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Kinase-like PF14531.6 CDJ90113.1 - 0.024 14.0 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like VASP_tetra PF08776.11 CDJ90113.1 - 0.12 11.9 1.3 2.4 7.8 0.1 2.8 2 0 0 2 2 2 0 VASP tetramerisation domain Calreticulin PF00262.18 CDJ90114.1 - 9.1e-86 288.0 23.6 4.4e-65 219.9 10.6 3.0 2 1 1 3 3 3 2 Calreticulin family TAF4 PF05236.14 CDJ90114.1 - 0.2 11.4 11.8 0.28 10.9 11.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family AAA_23 PF13476.6 CDJ90114.1 - 1.3 9.5 14.7 0.26 11.8 10.7 1.8 2 1 0 2 2 2 0 AAA domain MDM10 PF12519.8 CDJ90114.1 - 6.9 5.4 9.0 9.3 5.0 9.0 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF802 PF05650.11 CDJ90115.1 - 0.031 14.8 0.7 0.18 12.3 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF802) DUF4358 PF14270.6 CDJ90115.1 - 0.038 14.3 0.8 0.038 14.3 0.8 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4358) Actin PF00022.19 CDJ90116.1 - 9.7e-95 317.6 0.1 4.2e-94 315.4 0.1 1.7 1 1 0 1 1 1 1 Actin CAP_N PF01213.19 CDJ90118.1 - 9.2e-92 307.9 0.1 1.2e-91 307.5 0.1 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 CDJ90118.1 - 1.6e-58 196.8 3.6 2.3e-58 196.3 3.6 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 CDJ90118.1 - 0.00017 21.3 3.8 0.037 13.8 2.0 2.3 1 1 1 2 2 2 2 Tubulin binding cofactor C WH2 PF02205.20 CDJ90118.1 - 0.0053 16.5 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 WH2 motif LBP_C PF17386.2 CDJ90118.1 - 0.14 12.1 0.5 0.3 11.0 0.5 1.6 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase C-terminal domain LURAP PF14854.6 CDJ90118.1 - 0.16 12.0 0.0 0.41 10.6 0.0 1.6 1 0 0 1 1 1 0 Leucine rich adaptor protein KNOX2 PF03791.13 CDJ90119.1 - 0.088 12.3 0.2 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 KNOX2 domain EGF PF00008.27 CDJ90120.1 - 2.7e-08 34.0 20.4 2.8e-05 24.3 6.0 2.3 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 CDJ90120.1 - 1.8e-05 25.2 16.4 0.0046 17.5 5.7 2.7 2 0 0 2 2 2 2 Human growth factor-like EGF EGF_2 PF07974.13 CDJ90120.1 - 3.5e-05 24.1 26.6 0.0074 16.6 10.0 2.2 2 0 0 2 2 2 2 EGF-like domain Laminin_EGF PF00053.24 CDJ90120.1 - 0.026 14.7 19.0 0.66 10.2 5.8 2.3 1 1 1 2 2 2 0 Laminin EGF domain EGF_CA PF07645.15 CDJ90120.1 - 0.54 10.5 21.2 2.2 8.6 7.0 2.4 1 1 1 2 2 2 0 Calcium-binding EGF domain FXa_inhibition PF14670.6 CDJ90120.1 - 1.3 9.4 17.8 4.7 7.6 8.1 2.4 1 1 1 2 2 2 0 Coagulation Factor Xa inhibitory site COX15-CtaA PF02628.15 CDJ90121.1 - 0.0031 16.6 1.4 0.11 11.6 0.1 2.2 2 0 0 2 2 2 1 Cytochrome oxidase assembly protein Sulf_transp PF04143.14 CDJ90121.1 - 0.03 13.9 3.5 0.15 11.6 0.9 2.2 2 0 0 2 2 2 0 Sulphur transport DUF2207 PF09972.9 CDJ90121.1 - 0.058 12.2 7.8 0.05 12.4 0.2 3.1 3 1 1 4 4 4 0 Predicted membrane protein (DUF2207) 7TM_GPCR_Sru PF10322.9 CDJ90121.1 - 0.26 10.6 4.3 2.3 7.5 2.1 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sru DUF898 PF05987.13 CDJ90121.1 - 1.8 7.5 5.9 0.87 8.6 1.8 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) FtsX PF02687.21 CDJ90121.1 - 4.6 7.8 18.7 15 6.2 2.7 4.0 3 1 2 5 5 5 0 FtsX-like permease family Abhydrolase_9_N PF15420.6 CDJ90121.1 - 5.2 7.0 6.9 22 5.0 1.3 2.9 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus DUF3810 PF12725.7 CDJ90121.1 - 6.6 6.0 8.9 28 3.9 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3810) RT_RNaseH_2 PF17919.1 CDJ90122.1 - 8e-35 118.9 0.1 2.9e-34 117.1 0.1 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ90122.1 - 3.5e-33 114.0 0.0 1.7e-32 111.8 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ90122.1 - 5.9e-18 64.7 0.1 1.3e-17 63.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDJ90122.1 - 1.8e-10 41.0 0.0 4.4e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CDJ90122.1 - 5e-06 26.6 0.0 9.5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Neur_chan_LBD PF02931.23 CDJ90124.1 - 1.5e-57 194.5 4.4 2e-57 194.1 4.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ90124.1 - 7.9e-16 58.8 16.0 1.4e-14 54.7 16.0 2.2 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Exo_endo_phos_2 PF14529.6 CDJ90125.1 - 1.1e-06 28.5 0.0 1.9e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ90125.1 - 0.023 14.2 0.0 0.048 13.2 0.0 1.5 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 CDJ90126.1 - 2e-40 138.6 0.1 9.4e-40 136.5 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3629 PF12302.8 CDJ90126.1 - 0.024 14.1 2.9 0.039 13.4 2.1 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3629) RT_RNaseH_2 PF17919.1 CDJ90128.1 - 2.8e-34 117.1 0.1 9.4e-34 115.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ90128.1 - 9.6e-30 103.0 0.0 2.2e-29 101.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ90128.1 - 2.3e-13 50.2 0.0 6.3e-13 48.8 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Bcl-2 PF00452.19 CDJ90129.1 - 0.056 14.1 0.1 0.08 13.6 0.1 1.2 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family ALMT PF11744.8 CDJ90129.1 - 0.056 12.3 1.3 0.066 12.0 1.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter D5_N PF08706.11 CDJ90129.1 - 0.071 13.4 0.5 0.079 13.2 0.5 1.1 1 0 0 1 1 1 0 D5 N terminal like ORF11CD3 PF10549.9 CDJ90129.1 - 0.59 10.3 5.1 0.84 9.8 0.3 2.2 2 0 0 2 2 2 0 ORF11CD3 domain YtxH PF12732.7 CDJ90129.1 - 1 9.9 7.6 1.7 9.2 7.6 1.4 1 0 0 1 1 1 0 YtxH-like protein AP_endonuc_2 PF01261.24 CDJ90130.1 - 3.7e-36 124.6 0.0 4.6e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel rve PF00665.26 CDJ90130.1 - 0.022 14.9 0.2 1.3 9.3 0.0 2.5 3 0 0 3 3 3 0 Integrase core domain Cys_Met_Meta_PP PF01053.20 CDJ90131.1 - 3.2e-153 509.8 0.0 3.7e-153 509.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 CDJ90131.1 - 5.2e-08 31.8 0.0 6.5e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.21 CDJ90131.1 - 3.6e-05 23.1 0.0 5.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CDJ90131.1 - 0.0073 15.3 0.5 0.04 12.9 0.1 1.9 2 0 0 2 2 2 1 Aminotransferase class-V BCIP PF13862.6 CDJ90132.1 - 3.5e-30 105.3 0.3 3.5e-30 105.3 0.3 2.0 2 0 0 2 2 2 1 p21-C-terminal region-binding protein Astacin PF01400.24 CDJ90134.1 - 1.1e-52 178.4 0.1 2.2e-52 177.5 0.1 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB PF00431.20 CDJ90134.1 - 0.00038 20.8 0.2 0.00073 19.8 0.2 1.5 1 0 0 1 1 1 1 CUB domain Peptidase_M10 PF00413.24 CDJ90134.1 - 0.00054 19.8 1.9 0.0062 16.4 1.9 2.2 1 1 0 1 1 1 1 Matrixin ShK PF01549.24 CDJ90134.1 - 0.00059 20.3 4.8 0.0017 18.9 4.8 1.9 1 0 0 1 1 1 1 ShK domain-like Reprolysin_4 PF13583.6 CDJ90134.1 - 0.00059 19.5 0.1 0.001 18.8 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 CDJ90134.1 - 0.012 16.1 0.1 0.034 14.7 0.1 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 CDJ90134.1 - 0.019 14.2 0.3 0.036 13.3 0.3 1.3 1 0 0 1 1 1 0 Met-zincin CAGE1 PF15066.6 CDJ90134.1 - 0.035 12.8 1.9 0.058 12.1 1.9 1.2 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family Reprolysin_5 PF13688.6 CDJ90134.1 - 0.036 14.2 0.1 0.076 13.2 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Misat_Tub_SegII PF10644.9 CDJ90134.1 - 0.047 14.0 0.1 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 Misato Segment II tubulin-like domain BLM10_mid PF16507.5 CDJ90135.1 - 1.4e-46 159.3 17.3 5.7e-24 84.6 0.5 3.7 2 1 0 2 2 2 2 Proteasome-substrate-size regulator, mid region CFIA_Pcf11 PF11526.8 CDJ90135.1 - 0.019 15.4 0.2 1.3 9.6 0.1 2.6 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 TRAPP PF04051.16 CDJ90135.1 - 0.061 13.0 2.4 2.2 8.0 0.2 2.9 3 0 0 3 3 3 0 Transport protein particle (TRAPP) component EF-hand_2 PF09068.11 CDJ90135.1 - 0.11 12.6 3.0 2.5 8.3 1.3 3.6 4 1 0 4 4 4 0 EF hand I-set PF07679.16 CDJ90136.1 - 0 2393.7 125.1 1.1e-24 86.2 0.2 42.1 42 0 0 42 42 42 42 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ90136.1 - 0 1603.5 55.9 1.4e-15 57.6 0.0 42.2 42 0 0 42 42 42 42 Immunoglobulin domain Ig_2 PF13895.6 CDJ90136.1 - 8.5e-266 859.2 49.0 2.7e-09 37.2 0.0 42.2 41 1 1 42 42 42 39 Immunoglobulin domain ig PF00047.25 CDJ90136.1 - 7.5e-259 836.9 81.4 7.8e-13 48.4 0.2 41.7 42 0 0 42 42 42 33 Immunoglobulin domain V-set PF07686.17 CDJ90136.1 - 5.1e-124 406.3 108.4 2e-06 27.9 0.2 57.6 41 26 0 41 41 41 21 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDJ90136.1 - 9e-77 253.2 57.1 0.024 14.7 0.1 38.1 41 0 0 41 41 39 14 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.12 CDJ90136.1 - 8e-53 176.5 7.8 0.13 12.3 0.0 31.6 34 2 1 35 35 34 9 Penicillin-Binding Protein C-terminus Family Receptor_2B4 PF11465.8 CDJ90136.1 - 2.4e-52 175.7 14.3 0.28 11.4 0.0 29.6 32 0 0 32 32 29 4 Natural killer cell receptor 2B4 C1-set PF07654.15 CDJ90136.1 - 8.7e-29 99.8 79.8 0.11 12.9 0.1 33.7 38 0 0 38 38 34 4 Immunoglobulin C1-set domain Ig_6 PF18452.1 CDJ90136.1 - 2e-22 78.5 2.8 2.5 7.7 0.0 15.9 17 0 0 17 17 16 3 Immunoglobulin domain Ig_C17orf99 PF17736.1 CDJ90136.1 - 1.3e-20 73.3 6.4 0.087 12.9 0.0 19.6 25 0 0 25 25 20 2 C17orf99 Ig domain Izumo-Ig PF16706.5 CDJ90136.1 - 1.8e-20 72.8 42.6 0.16 12.0 0.0 23.8 27 0 0 27 27 21 2 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 CDJ90136.1 - 1.2e-15 57.6 50.9 0.037 14.3 0.1 26.9 34 0 0 34 34 29 2 T-cell surface glycoprotein CD3 delta chain V-set_CD47 PF08204.11 CDJ90136.1 - 5.6e-13 49.0 27.3 0.027 14.5 0.1 17.9 21 0 0 21 21 19 1 CD47 immunoglobulin-like domain SusF_SusE PF16411.5 CDJ90136.1 - 6.4e-10 39.7 0.0 7 7.2 0.0 10.5 8 3 2 10 10 8 0 Outer membrane protein SusF_SusE Alpha-amyl_C PF09071.10 CDJ90136.1 - 9.9e-07 28.5 0.0 2.4 8.1 0.0 4.5 4 0 0 4 4 4 2 Alpha-amylase, C terminal CD4-extracel PF09191.10 CDJ90136.1 - 4.9e-06 26.9 0.0 20 5.7 0.0 6.6 6 0 0 6 6 5 0 CD4, extracellular Big_3_5 PF16640.5 CDJ90136.1 - 1.3e-05 25.3 55.3 1.2 9.4 0.4 13.8 14 0 0 14 14 11 1 Bacterial Ig-like domain (group 3) Egh16-like PF11327.8 CDJ90136.1 - 9.8e-05 22.8 13.1 0.21 12.0 0.0 7.7 7 2 0 8 8 5 2 Egh16-like virulence factor P_proprotein PF01483.20 CDJ90136.1 - 0.0019 18.2 2.7 1.3e+02 2.7 0.0 8.8 12 0 0 12 12 7 0 Proprotein convertase P-domain MG2 PF01835.19 CDJ90136.1 - 0.0019 18.6 24.8 37 4.9 0.0 15.8 19 0 0 19 19 15 0 MG2 domain BsuPI PF12690.7 CDJ90136.1 - 0.0024 17.9 7.0 40 4.3 0.0 9.2 9 1 1 10 10 7 0 Intracellular proteinase inhibitor DUF1857 PF08982.11 CDJ90136.1 - 0.0053 16.6 12.7 0.12 12.2 0.1 6.3 7 0 0 7 7 4 1 Domain of unknown function (DUF1857) NGP1NT PF08153.12 CDJ90136.1 - 0.006 16.7 0.1 2.3 8.4 0.0 3.7 2 0 0 2 2 2 1 NGP1NT (NUC091) domain DUF4871 PF16167.5 CDJ90136.1 - 0.01 15.8 0.3 3 7.9 0.1 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4871) FGGY_N PF00370.21 CDJ90136.1 - 0.02 14.4 0.3 6 6.4 0.0 4.4 5 0 0 5 5 4 0 FGGY family of carbohydrate kinases, N-terminal domain DUF3821 PF12863.7 CDJ90136.1 - 0.025 14.5 11.8 12 5.7 0.1 7.1 3 1 3 6 6 5 0 Domain of unknown function (DUF3821) CBM_48 PF02922.18 CDJ90136.1 - 0.039 14.3 1.4 1.6e+02 2.7 0.0 7.3 9 0 0 9 9 4 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 53-BP1_Tudor PF09038.10 CDJ90136.1 - 0.062 13.3 1.1 19 5.2 0.0 4.7 2 1 3 5 5 5 0 Tumour suppressor p53-binding protein-1 Tudor pPIWI_RE_REase PF18154.1 CDJ90136.1 - 0.099 12.6 3.1 39 4.2 0.0 5.0 5 1 1 6 6 5 0 REase associating with pPIWI_RE DUF1533 PF07550.11 CDJ90136.1 - 0.15 12.0 4.1 15 5.6 0.1 5.4 4 0 0 4 4 3 0 Protein of unknown function (DUF1533) Glyco_hydro_30C PF17189.4 CDJ90136.1 - 0.16 12.2 1.0 26 5.1 0.1 5.3 3 0 0 3 3 2 0 Glycosyl hydrolase family 30 beta sandwich domain A2M PF00207.22 CDJ90136.1 - 0.24 11.3 11.0 3.2 7.7 0.9 6.6 6 0 0 6 6 5 0 Alpha-2-macroglobulin family Mfa2 PF08842.10 CDJ90136.1 - 1.7 8.1 8.1 6.9 6.2 0.1 5.6 6 1 1 7 7 5 0 Fimbrillin-A associated anchor proteins Mfa1 and Mfa2 C2-set PF05790.15 CDJ90136.1 - 2.2 8.5 36.3 20 5.4 0.0 14.1 18 0 0 18 18 12 0 Immunoglobulin C2-set domain fn3 PF00041.21 CDJ90137.1 - 5.6e-222 718.8 7.6 5e-17 62.0 0.0 15.4 15 0 0 15 15 14 14 Fibronectin type III domain I-set PF07679.16 CDJ90137.1 - 7.3e-211 683.0 35.6 1.9e-19 69.5 0.1 20.0 21 0 0 21 21 21 15 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ90137.1 - 2.1e-125 409.6 14.7 2.2e-12 47.4 0.1 16.8 15 0 0 15 15 15 14 Immunoglobulin domain ig PF00047.25 CDJ90137.1 - 5.7e-59 196.3 18.5 1.6e-06 28.2 0.0 14.7 14 0 0 14 14 14 10 Immunoglobulin domain Ig_2 PF13895.6 CDJ90137.1 - 1.7e-53 178.9 13.9 1.1e-05 25.6 0.0 14.3 13 1 1 14 14 14 11 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 CDJ90137.1 - 4.3e-33 113.8 2.2 0.41 11.2 0.1 15.9 15 2 0 15 15 15 6 Purple acid Phosphatase, N-terminal domain V-set PF07686.17 CDJ90137.1 - 1.2e-32 112.3 13.4 0.019 15.1 0.3 16.0 14 3 1 15 15 14 7 Immunoglobulin V-set domain Y_Y_Y PF07495.13 CDJ90137.1 - 2.9e-17 62.4 6.0 0.61 10.1 0.0 12.3 13 0 0 13 13 12 4 Y_Y_Y domain fn3_4 PF16794.5 CDJ90137.1 - 1.3e-12 47.5 0.0 0.021 14.7 0.0 10.8 11 0 0 11 11 11 1 Fibronectin-III type domain DUF2369 PF10179.9 CDJ90137.1 - 7.7e-11 42.2 0.0 4.9 7.6 0.0 10.6 13 0 0 13 13 12 1 Uncharacterised conserved protein (DUF2369) Receptor_2B4 PF11465.8 CDJ90137.1 - 1.3e-10 41.5 1.6 11 6.3 0.0 10.6 12 0 0 12 12 11 0 Natural killer cell receptor 2B4 C2-set_2 PF08205.12 CDJ90137.1 - 6.8e-10 38.9 10.8 0.58 10.3 0.0 9.6 10 0 0 10 10 10 1 CD80-like C2-set immunoglobulin domain Tissue_fac PF01108.17 CDJ90137.1 - 6.9e-08 32.3 0.0 1.1 9.1 0.0 9.0 11 0 0 11 11 10 1 Tissue factor Interfer-bind PF09294.10 CDJ90137.1 - 1.2e-06 28.8 0.0 4.7 7.6 0.0 8.2 9 0 0 9 9 8 1 Interferon-alpha/beta receptor, fibronectin type III PhoD_N PF16655.5 CDJ90137.1 - 1.4e-06 28.7 0.1 11 6.7 0.0 7.8 9 0 0 9 9 7 0 PhoD-like phosphatase, N-terminal domain DUF4959 PF16323.5 CDJ90137.1 - 1.9e-06 28.1 0.1 3.1 8.2 0.0 7.7 7 0 0 7 7 7 1 Domain of unknown function (DUF4959) CRISPR_assoc PF08798.11 CDJ90137.1 - 1.2e-05 25.5 0.1 51 3.9 0.0 7.9 9 0 0 9 9 9 0 CRISPR associated protein DUF11 PF01345.18 CDJ90137.1 - 1.4e-05 25.3 6.6 3.7 7.9 0.0 8.8 9 2 0 9 9 8 1 Domain of unknown function DUF11 DUF756 PF05506.12 CDJ90137.1 - 9.3e-05 23.3 5.6 34 5.5 0.0 9.8 11 1 0 11 11 8 0 Domain of unknown function (DUF756) Ig_6 PF18452.1 CDJ90137.1 - 0.00011 21.7 0.0 24 4.6 0.0 5.0 4 0 0 4 4 4 0 Immunoglobulin domain Izumo-Ig PF16706.5 CDJ90137.1 - 0.00014 21.8 6.9 1.6 8.9 0.0 6.7 8 1 0 8 8 5 2 Izumo-like Immunoglobulin domain DUF4198 PF10670.9 CDJ90137.1 - 0.0004 20.8 19.3 4.2 7.7 0.1 8.1 6 1 1 7 7 7 2 Domain of unknown function (DUF4198) Ig_4 PF16680.5 CDJ90137.1 - 0.0065 16.7 12.8 0.37 11.1 0.1 6.7 7 0 0 7 7 7 1 T-cell surface glycoprotein CD3 delta chain AMP-binding_C_2 PF14535.6 CDJ90137.1 - 0.0085 16.4 0.0 28 5.1 0.0 5.1 5 0 0 5 5 5 0 AMP-binding enzyme C-terminal domain Big_2 PF02368.18 CDJ90137.1 - 0.5 10.3 3.8 1.1 9.2 0.1 3.9 3 0 0 3 3 2 0 Bacterial Ig-like domain (group 2) Big_1 PF02369.16 CDJ90137.1 - 1.7 8.7 9.5 20 5.2 0.0 5.6 5 1 1 6 6 6 0 Bacterial Ig-like domain (group 1) Dynein_light PF01221.18 CDJ90138.1 - 3.4e-44 149.1 1.5 4e-44 148.9 1.5 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Nop PF01798.18 CDJ90138.1 - 0.046 13.2 0.0 0.051 13.0 0.0 1.0 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin NOPS PF08075.11 CDJ90139.1 - 2.6e-11 43.5 0.4 5.1e-11 42.6 0.4 1.5 1 0 0 1 1 1 1 NOPS (NUC059) domain HIP1_clath_bdg PF16515.5 CDJ90139.1 - 0.13 12.9 8.8 0.22 12.2 8.8 1.2 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1679 PF07914.11 CDJ90142.1 - 1e-43 149.8 0.0 1.3e-43 149.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.23 CDJ90142.1 - 5.8e-13 49.3 0.1 2.7e-12 47.1 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CDJ90142.1 - 2e-11 43.8 0.0 3e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 CDJ90142.1 - 0.0069 16.0 0.3 0.018 14.6 0.3 1.8 1 1 0 1 1 1 1 RIO1 family Sec2p PF06428.11 CDJ90143.1 - 1.7e-05 24.7 2.1 1.7e-05 24.7 2.1 2.1 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p TBK1_CCD1 PF18394.1 CDJ90143.1 - 0.0069 16.0 1.4 0.011 15.3 1.4 1.2 1 0 0 1 1 1 1 TANK-binding kinase 1 coiled-coil domain 1 CorA PF01544.18 CDJ90143.1 - 0.04 13.2 1.1 0.067 12.5 1.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Lipoprotein_20 PF13942.6 CDJ90143.1 - 0.058 13.3 3.2 0.1 12.5 3.2 1.3 1 0 0 1 1 1 0 YfhG lipoprotein Fez1 PF06818.15 CDJ90143.1 - 0.09 13.2 8.2 0.18 12.3 8.2 1.4 1 0 0 1 1 1 0 Fez1 7TMR-HDED PF07697.11 CDJ90143.1 - 2.6 8.1 10.7 2.5 8.2 0.5 2.1 1 1 1 2 2 2 0 7TM-HD extracellular HTH_26 PF13443.6 CDJ90144.1 - 0.001 19.5 0.1 0.0019 18.6 0.1 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain MarR_2 PF12802.7 CDJ90144.1 - 0.0081 16.0 0.1 0.019 14.8 0.1 1.6 1 0 0 1 1 1 1 MarR family LacI PF00356.21 CDJ90144.1 - 0.0092 15.8 0.1 0.0092 15.8 0.1 2.1 3 0 0 3 3 3 1 Bacterial regulatory proteins, lacI family HTH_24 PF13412.6 CDJ90144.1 - 0.017 14.6 0.1 0.034 13.7 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 CDJ90144.1 - 0.018 14.9 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain CENP-B_N PF04218.13 CDJ90144.1 - 0.079 12.6 0.0 0.17 11.5 0.0 1.6 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_10 PF04967.12 CDJ90144.1 - 0.12 12.2 0.1 0.43 10.4 0.1 2.0 2 0 0 2 2 2 0 HTH DNA binding domain E3_UFM1_ligase PF09743.9 CDJ90144.1 - 0.13 11.9 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 E3 UFM1-protein ligase 1 eIF3_N PF09440.10 CDJ90145.1 - 0.0015 19.0 2.4 0.0032 17.9 1.1 2.1 2 1 1 3 3 3 1 eIF3 subunit 6 N terminal domain Myb_DNA-bind_5 PF13873.6 CDJ90145.1 - 0.013 15.6 0.1 0.037 14.1 0.1 1.9 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CDJ90145.1 - 0.049 14.0 0.5 0.049 14.0 0.5 2.4 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Laminin_G_2 PF02210.24 CDJ90147.1 - 6.5e-103 340.2 5.2 7.5e-24 84.7 0.0 6.2 6 0 0 6 6 6 6 Laminin G domain Laminin_G_1 PF00054.23 CDJ90147.1 - 8.5e-75 249.2 0.1 6.5e-21 74.9 0.0 6.3 6 0 0 6 6 6 6 Laminin G domain EGF PF00008.27 CDJ90147.1 - 1.8e-08 34.5 37.0 0.00035 20.8 8.7 4.0 4 0 0 4 4 4 3 EGF-like domain Laminin_G_3 PF13385.6 CDJ90147.1 - 6.9e-05 23.0 5.3 1.5 9.0 0.0 5.3 6 0 0 6 6 6 2 Concanavalin A-like lectin/glucanases superfamily Cadherin_C_2 PF16492.5 CDJ90147.1 - 0.0019 18.9 0.0 0.006 17.3 0.0 1.8 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal hEGF PF12661.7 CDJ90147.1 - 0.002 18.7 30.5 0.59 10.9 4.0 4.0 3 0 0 3 3 3 3 Human growth factor-like EGF EGF_2 PF07974.13 CDJ90147.1 - 0.083 13.3 44.2 0.12 12.7 6.9 4.2 4 0 0 4 4 4 0 EGF-like domain MBOAT PF03062.19 CDJ90149.1 - 7.3e-31 107.8 26.4 2.4e-30 106.1 26.4 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 CDJ90149.1 - 0.00011 22.4 8.1 0.00017 21.8 5.9 2.5 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Mt_ATP-synt_D PF05873.12 CDJ90150.1 - 3e-36 124.6 1.1 3.9e-36 124.2 1.1 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) adh_short PF00106.25 CDJ90151.1 - 5.7e-27 94.4 0.0 3.1e-26 92.0 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ90151.1 - 3.5e-14 52.9 0.1 8.8e-14 51.6 0.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ90151.1 - 2.3e-11 43.9 0.0 3.7e-11 43.2 0.0 1.4 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 CDJ90151.1 - 0.0004 20.6 0.2 0.0036 17.6 0.1 2.4 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 CDJ90151.1 - 0.014 14.8 0.2 0.07 12.6 0.2 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CDJ90151.1 - 0.021 14.0 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF825 PF05695.12 CDJ90151.1 - 0.063 10.4 0.1 0.081 10.1 0.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) adh_short PF00106.25 CDJ90152.1 - 3.4e-06 26.6 0.0 6.6e-05 22.4 0.0 2.4 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ90152.1 - 0.0065 16.0 0.0 0.054 13.1 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1075 PF06388.11 CDJ90153.1 - 5 7.2 7.3 2.2 8.4 2.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1075) DZF PF07528.14 CDJ90154.1 - 4.1e-76 255.9 0.3 8.7e-76 254.8 0.0 1.6 2 0 0 2 2 2 1 DZF domain Na_K-ATPase PF00287.18 CDJ90155.1 - 8.6e-13 48.1 0.0 2.5e-12 46.6 0.0 1.7 1 1 0 1 1 1 1 Sodium / potassium ATPase beta chain DUF2484 PF10658.9 CDJ90156.1 - 0.18 12.1 0.1 0.28 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) ShK PF01549.24 CDJ90157.1 - 2.3e-13 50.4 53.1 0.00033 21.1 2.6 5.2 5 1 0 5 5 5 4 ShK domain-like BLM10_mid PF16507.5 CDJ90158.1 - 3.1e-55 187.8 7.6 4.7e-30 104.7 0.0 3.3 3 0 0 3 3 3 3 Proteasome-substrate-size regulator, mid region Topoisom_bac PF01131.20 CDJ90159.1 - 1.5e-45 156.0 0.2 1.8e-45 155.7 0.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CDJ90159.1 - 4.5e-19 68.6 0.0 1e-18 67.5 0.0 1.6 1 0 0 1 1 1 1 Toprim domain zf-H2C2_2 PF13465.6 CDJ90160.1 - 1.7e-13 50.3 29.6 5e-06 26.7 1.4 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 CDJ90160.1 - 2e-12 46.8 27.3 5e-06 26.7 1.2 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ90160.1 - 3.3e-10 39.9 26.8 7.1e-05 23.3 1.2 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CDJ90160.1 - 9.7e-07 28.4 9.9 2.2e-05 24.1 0.3 3.4 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 CDJ90160.1 - 4.7e-06 26.7 7.5 0.0022 18.3 0.1 3.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CDJ90160.1 - 0.00039 20.6 1.6 0.00039 20.6 1.6 3.1 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 CDJ90160.1 - 0.0035 17.1 0.7 0.016 15.0 0.4 2.2 1 1 1 2 2 2 1 GAGA factor zf-C2HE PF16278.5 CDJ90160.1 - 0.017 15.6 7.4 0.24 11.9 0.1 3.5 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Cys_rich_CPCC PF14206.6 CDJ90160.1 - 0.017 14.9 3.0 3.4 7.6 0.1 3.5 3 0 0 3 3 3 0 Cysteine-rich CPCC DUF3268 PF11672.8 CDJ90160.1 - 0.026 14.8 0.3 0.026 14.8 0.3 2.1 3 0 0 3 3 2 0 zinc-finger-containing domain zf-C2H2_8 PF15909.5 CDJ90160.1 - 0.061 13.6 8.1 1 9.7 1.0 2.9 2 1 1 3 3 3 0 C2H2-type zinc ribbon Rpr2 PF04032.16 CDJ90160.1 - 0.12 12.7 1.6 0.29 11.5 0.3 2.2 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn-ribbon_8 PF09723.10 CDJ90160.1 - 0.14 12.3 12.1 0.18 11.9 0.8 3.4 3 0 0 3 3 3 0 Zinc ribbon domain DZR PF12773.7 CDJ90160.1 - 0.19 11.8 8.6 0.2 11.7 2.1 3.0 2 1 1 3 3 3 0 Double zinc ribbon zf-Mss51 PF13824.6 CDJ90160.1 - 0.21 11.7 7.1 3.3 7.9 0.2 3.1 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-TRAF PF02176.18 CDJ90160.1 - 0.37 11.5 12.1 1.3 9.8 0.7 3.2 3 0 0 3 3 3 0 TRAF-type zinc finger HypA PF01155.19 CDJ90160.1 - 0.66 10.0 9.4 3.9 7.5 2.3 3.1 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.5 CDJ90160.1 - 0.84 10.4 8.3 0.33 11.7 2.0 2.9 2 1 1 3 3 3 0 zinc-ribbon family zf_C2H2_ZHX PF18387.1 CDJ90160.1 - 1.1 8.9 15.5 1.2 8.8 0.1 3.7 2 1 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain YHS PF04945.13 CDJ90160.1 - 1.2 9.3 6.8 0.56 10.4 1.1 2.7 3 0 0 3 3 2 0 YHS domain DUF629 PF04780.12 CDJ90160.1 - 1.9 6.9 5.8 26 3.2 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF629) zf-AN1 PF01428.16 CDJ90160.1 - 8 6.7 12.0 6.5 7.0 0.2 4.0 4 0 0 4 4 4 0 AN1-like Zinc finger zf-C2H2_6 PF13912.6 CDJ90160.1 - 9.6 6.3 22.1 0.49 10.5 0.7 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger UDG PF03167.19 CDJ90161.1 - 1.3e-23 83.7 0.0 1.9e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily CCDC106 PF15794.5 CDJ90162.1 - 1.4 8.5 11.8 0.097 12.4 5.1 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Homeodomain PF00046.29 CDJ90163.1 - 5.9e-22 77.3 2.5 8.9e-22 76.7 2.5 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ90163.1 - 0.004 17.0 0.0 0.01 15.7 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain STIL_N PF15253.6 CDJ90163.1 - 0.071 12.1 1.6 0.044 12.7 0.4 1.2 1 1 0 1 1 1 0 SCL-interrupting locus protein N-terminus PA26 PF04636.13 CDJ90164.1 - 0.54 9.1 2.8 0.88 8.4 2.8 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Peptidase_M24 PF00557.24 CDJ90165.1 - 3.2e-28 98.9 0.3 6.9e-28 97.8 0.3 1.7 1 1 0 1 1 1 1 Metallopeptidase family M24 zf-H2C2_2 PF13465.6 CDJ90166.1 - 0.002 18.5 8.9 0.077 13.5 0.3 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-RanBP PF00641.18 CDJ90166.1 - 0.0046 16.2 4.7 0.37 10.2 0.9 2.8 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others Endonuclease_7 PF02945.15 CDJ90166.1 - 0.0067 16.3 3.1 0.0067 16.3 3.1 2.1 2 0 0 2 2 2 1 Recombination endonuclease VII DUF2063 PF09836.9 CDJ90166.1 - 0.044 14.0 0.1 2.7 8.3 0.1 2.4 2 0 0 2 2 2 0 Putative DNA-binding domain DUF2752 PF10825.8 CDJ90166.1 - 0.1 12.7 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) Zn_ribbon_SprT PF17283.2 CDJ90166.1 - 0.23 11.4 4.1 0.47 10.4 0.2 2.7 3 0 0 3 3 3 0 SprT-like zinc ribbon domain HypA PF01155.19 CDJ90166.1 - 0.96 9.5 5.5 0.36 10.9 1.9 2.1 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-TRAF PF02176.18 CDJ90166.1 - 1.2 9.8 8.3 0.77 10.5 4.5 2.4 2 0 0 2 2 2 0 TRAF-type zinc finger Spermine_synth PF01564.17 CDJ90167.1 - 1.1e-05 25.0 0.1 2.2e-05 24.0 0.1 1.4 1 1 0 1 1 1 1 Spermine/spermidine synthase domain MTS PF05175.14 CDJ90167.1 - 0.00046 19.8 0.0 0.00071 19.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CDJ90167.1 - 0.0056 17.4 0.0 0.014 16.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Viral_helicase1 PF01443.18 CDJ90167.1 - 0.094 12.4 0.0 3.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase CAP PF00188.26 CDJ90168.1 - 2.4e-09 38.1 3.9 3.3e-09 37.7 3.9 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ATP-synt_F6 PF05511.11 CDJ90169.1 - 0.07 13.5 0.0 0.1 13.0 0.0 1.5 1 1 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 HD_3 PF13023.6 CDJ90170.1 - 1.6e-25 89.9 0.0 1.9e-25 89.7 0.0 1.0 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 CDJ90170.1 - 3.8e-08 33.3 0.0 4.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 CDJ90170.1 - 0.0072 16.5 0.1 0.0088 16.3 0.1 1.2 1 0 0 1 1 1 1 HD domain ANAPC4_WD40 PF12894.7 CDJ90171.1 - 0.00068 19.9 0.0 0.017 15.4 0.0 3.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain zf-C3H2C3 PF17122.5 CDJ90171.1 - 0.27 11.3 5.3 1.5 8.9 5.3 2.5 1 1 0 1 1 1 0 Zinc-finger zf-rbx1 PF12678.7 CDJ90171.1 - 0.46 10.8 6.0 0.5 10.7 2.0 3.0 2 1 0 2 2 2 0 RING-H2 zinc finger domain Yos1 PF08571.10 CDJ90172.1 - 4.1e-27 94.3 0.5 4.6e-27 94.1 0.5 1.0 1 0 0 1 1 1 1 Yos1-like CLTH PF10607.9 CDJ90173.1 - 2.4e-26 92.4 0.7 4.1e-26 91.6 0.1 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Musclin PF11037.8 CDJ90173.1 - 0.01 15.8 0.2 0.022 14.7 0.2 1.5 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle FemAB_like PF04339.12 CDJ90173.1 - 0.04 13.0 0.8 0.064 12.4 0.8 1.3 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition FAA_hydrolase_N PF09298.11 CDJ90173.1 - 0.087 13.0 4.2 0.098 12.8 2.1 2.1 1 1 1 2 2 2 0 Fumarylacetoacetase N-terminal ECH_1 PF00378.20 CDJ90174.1 - 5.7e-36 124.1 0.0 8e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CDJ90174.1 - 7.8e-24 84.8 0.0 9.3e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ANTH PF07651.16 CDJ90175.1 - 1.7e-70 237.2 0.3 3.9e-70 236.0 0.1 1.6 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.20 CDJ90175.1 - 7.3e-14 51.9 0.1 1.4e-13 51.0 0.1 1.4 1 0 0 1 1 1 1 ENTH domain PhoLip_ATPase_C PF16212.5 CDJ90176.1 - 7e-48 163.6 23.1 7e-48 163.6 23.1 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CDJ90176.1 - 3.4e-19 68.3 0.7 8.1e-19 67.1 0.7 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CDJ90176.1 - 7.5e-16 58.2 0.2 7.5e-16 58.2 0.2 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CDJ90176.1 - 1.4e-14 54.9 0.2 4.3e-12 46.8 0.2 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDJ90176.1 - 5.5e-10 39.2 0.0 1.6e-08 34.5 0.0 2.9 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CDJ90176.1 - 0.0018 18.1 0.0 0.0048 16.7 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Aph-1 PF06105.12 CDJ90177.1 - 3.2e-56 190.3 14.9 4e-56 190.0 14.9 1.0 1 0 0 1 1 1 1 Aph-1 protein Collagen PF01391.18 CDJ90178.1 - 4.7e-14 51.9 162.4 1.9e-10 40.4 35.8 5.4 2 2 2 4 4 4 3 Collagen triple helix repeat (20 copies) EF-hand_1 PF00036.32 CDJ90179.1 - 2e-13 48.8 5.1 4e-06 26.0 0.9 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDJ90179.1 - 7.3e-11 42.4 4.3 8.7e-11 42.1 4.3 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ90179.1 - 1e-10 40.6 2.7 1.9e-05 24.2 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDJ90179.1 - 8.9e-07 28.1 3.3 0.014 14.9 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDJ90179.1 - 1.2e-06 28.2 1.9 0.0051 16.6 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair DUF5446 PF17522.2 CDJ90179.1 - 0.0018 18.4 0.1 0.0029 17.7 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5446) zf-HC5HC2H_2 PF13832.6 CDJ90180.1 - 2.2e-32 111.5 7.5 2.2e-32 111.5 7.5 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CDJ90180.1 - 8.7e-23 80.4 5.1 8.7e-23 80.4 5.1 3.3 2 1 1 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 CDJ90180.1 - 2e-11 43.3 4.7 2e-11 43.3 4.7 3.4 3 0 0 3 3 3 1 PHD-finger PHD PF00628.29 CDJ90180.1 - 4.9e-09 35.9 31.1 7.5e-09 35.4 12.0 3.6 3 0 0 3 3 3 2 PHD-finger RNF111_N PF15303.6 CDJ90180.1 - 0.018 14.9 0.3 0.039 13.7 0.1 1.7 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase Arkadia N-terminus AT_hook PF02178.19 CDJ90180.1 - 0.018 14.8 5.2 0.056 13.3 5.2 1.9 1 0 0 1 1 1 0 AT hook motif EPL1 PF10513.9 CDJ90180.1 - 0.062 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Enhancer of polycomb-like zf-CCCH_4 PF18044.1 CDJ90181.1 - 6.9e-11 41.7 17.1 7.9e-05 22.4 3.3 3.7 3 0 0 3 3 3 3 CCCH-type zinc finger zf-CCCH PF00642.24 CDJ90181.1 - 1.1e-06 28.4 19.9 2e-06 27.5 0.9 3.8 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CDJ90181.1 - 6.3e-06 26.8 11.8 0.0099 16.6 0.6 3.3 1 1 2 3 3 3 2 Torus domain zf-CCCH_3 PF15663.5 CDJ90181.1 - 3.7e-05 23.9 9.3 0.0091 16.2 3.6 2.3 2 0 0 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 CDJ90181.1 - 0.00032 21.1 21.5 0.017 15.6 4.6 3.5 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 CDJ90181.1 - 0.005 16.9 4.8 0.005 16.9 4.8 4.7 4 1 0 4 4 4 2 Zinc finger domain Cnn_1N PF07989.11 CDJ90181.1 - 0.0073 16.4 4.2 0.015 15.4 4.2 1.4 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 bZIP_2 PF07716.15 CDJ90181.1 - 0.038 14.1 3.5 0.038 14.1 3.5 1.9 2 0 0 2 2 2 0 Basic region leucine zipper FlaC_arch PF05377.11 CDJ90181.1 - 0.39 11.2 2.3 0.62 10.5 2.3 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) CENP-Q PF13094.6 CDJ90181.1 - 3.7 7.7 8.1 7.7 6.7 8.1 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Ras PF00071.22 CDJ90182.1 - 9.2e-55 184.7 0.0 1.1e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ90182.1 - 4.9e-21 75.2 0.0 7.2e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ90182.1 - 5.5e-09 35.7 0.0 6.3e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CDJ90182.1 - 7.6e-07 29.2 0.0 0.0022 17.9 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CDJ90182.1 - 0.00023 20.8 0.0 0.00066 19.3 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CDJ90182.1 - 0.0073 15.8 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 CDJ90182.1 - 0.011 15.3 0.0 0.035 13.6 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1 PF01926.23 CDJ90182.1 - 0.014 15.5 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CDJ90182.1 - 0.034 13.9 0.4 0.13 12.0 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ATPgrasp_Ter PF15632.6 CDJ90182.1 - 0.048 13.4 0.0 0.31 10.8 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon AAA_25 PF13481.6 CDJ90182.1 - 0.05 13.2 0.2 0.15 11.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 CDJ90182.1 - 0.091 12.0 0.0 3 7.0 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_22 PF13401.6 CDJ90182.1 - 0.14 12.4 0.1 2.9 8.2 0.1 2.3 2 1 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 CDJ90182.1 - 0.15 11.4 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ACT_7 PF13840.6 CDJ90184.1 - 0.024 14.4 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 ACT domain MPTase-PolyVal PF18818.1 CDJ90184.1 - 0.19 11.8 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Metallopeptidase superfamily domain Ras PF00071.22 CDJ90186.1 - 1.2e-49 168.0 0.0 1.4e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ90186.1 - 1.7e-18 67.0 0.1 3.3e-18 66.0 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ90186.1 - 1.8e-08 34.1 0.0 2.1e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDJ90186.1 - 2.1e-05 24.2 0.1 4.6e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CDJ90186.1 - 0.00025 21.3 1.3 0.27 11.5 0.1 2.6 2 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 CDJ90186.1 - 0.00087 19.2 0.4 0.74 9.7 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CDJ90186.1 - 0.001 19.2 0.0 0.0023 18.0 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 CDJ90186.1 - 0.022 14.5 0.0 0.037 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain ParA PF10609.9 CDJ90186.1 - 0.043 13.3 0.1 0.07 12.6 0.1 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase BLOC1_2 PF10046.9 CDJ90187.1 - 0.034 14.4 0.1 0.099 13.0 0.1 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UPA_2 PF17809.1 CDJ90188.1 - 4.6e-45 152.7 0.0 8.7e-45 151.8 0.0 1.5 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 CDJ90188.1 - 3.8e-34 117.0 0.9 2.7e-27 95.0 0.0 2.7 2 0 0 2 2 2 2 ZU5 domain Death PF00531.22 CDJ90188.1 - 9e-15 54.6 0.0 2.1e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Death domain BLOC1_2 PF10046.9 CDJ90189.1 - 0.022 15.0 0.3 0.057 13.7 0.3 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 G_glu_transpept PF01019.21 CDJ90190.1 - 2.3e-95 320.3 0.0 2.8e-95 320.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Neur_chan_LBD PF02931.23 CDJ90192.1 - 1.2e-42 145.8 0.3 1.7e-42 145.3 0.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ90192.1 - 6e-25 88.7 0.7 2.9e-23 83.2 0.7 2.3 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region cEGF PF12662.7 CDJ90192.1 - 0.12 12.3 1.1 0.27 11.2 1.1 1.6 1 0 0 1 1 1 0 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 CDJ90192.1 - 0.7 10.0 6.9 2 8.5 6.9 1.9 1 0 0 1 1 1 0 MSP1 EGF domain 1 DUF1467 PF07330.12 CDJ90195.1 - 1.2 9.2 0.0 1.2 9.2 0.0 3.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1467) Nop14 PF04147.12 CDJ90195.1 - 1.3 7.1 22.1 1.4 7.1 22.1 1.1 1 0 0 1 1 1 0 Nop14-like family PLDc_3 PF13918.6 CDJ90196.1 - 4.1e-24 85.2 0.0 1.9e-23 83.0 0.0 1.9 2 0 0 2 2 2 1 PLD-like domain PLDc_2 PF13091.6 CDJ90196.1 - 5.7e-24 84.5 0.0 5.4e-12 45.8 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CDJ90196.1 - 6.3e-10 38.8 3.9 3.4e-06 27.0 0.4 3.0 3 0 0 3 3 3 2 Phospholipase D Active site motif MRP-S28 PF10213.9 CDJ90197.1 - 6e-20 71.9 0.4 1.2e-19 71.0 0.4 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF1325 PF07039.11 CDJ90197.1 - 0.083 13.0 0.1 0.25 11.4 0.1 1.8 2 0 0 2 2 2 0 SGF29 tudor-like domain EF-hand_4 PF12763.7 CDJ90200.1 - 1.3e-11 44.3 0.0 3.4e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand APG6_N PF17675.1 CDJ90200.1 - 0.06 13.9 3.2 2.6 8.6 1.8 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region EF-hand_7 PF13499.6 CDJ90200.1 - 0.093 13.2 0.1 0.65 10.5 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair QVR PF17064.5 CDJ90201.1 - 0.15 12.3 3.0 0.3 11.4 2.5 1.8 1 1 0 1 1 1 0 Sleepless protein Kunitz_BPTI PF00014.23 CDJ90202.1 - 1.6e-30 105.1 4.1 1.6e-15 57.1 1.1 2.6 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Shisa PF13908.6 CDJ90202.1 - 0.017 15.4 1.8 0.017 15.3 0.0 1.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator QVR PF17064.5 CDJ90202.1 - 0.032 14.4 1.9 0.11 12.7 0.4 2.5 2 0 0 2 2 2 0 Sleepless protein Fig1 PF12351.8 CDJ90202.1 - 0.083 12.8 0.5 0.27 11.1 0.1 2.0 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Baculo_11_kDa PF06143.11 CDJ90202.1 - 4.1 7.1 5.8 9.1 5.9 5.8 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family Kunitz_BPTI PF00014.23 CDJ90203.1 - 1.5e-30 105.2 4.2 1.5e-15 57.2 2.0 2.6 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain QVR PF17064.5 CDJ90203.1 - 1 9.6 6.8 0.2 11.9 2.0 2.3 3 0 0 3 3 3 0 Sleepless protein Metallophos PF00149.28 CDJ90204.1 - 5e-41 141.4 0.0 6.6e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDJ90204.1 - 3.1e-16 59.5 0.5 5.5e-16 58.7 0.5 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 CDJ90205.1 - 2.5e-40 139.2 0.1 3.1e-40 138.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDJ90205.1 - 3.5e-22 78.6 0.4 9e-22 77.3 0.3 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Homeodomain PF00046.29 CDJ90206.1 - 6.3e-20 70.8 6.9 9.5e-20 70.2 6.9 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ90206.1 - 0.0073 16.2 0.1 0.015 15.2 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain TRAPP PF04051.16 CDJ90207.1 - 1.9e-40 138.0 0.1 2.2e-40 137.8 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Piwi PF02171.17 CDJ90208.1 - 6.6e-75 252.1 0.3 9.8e-75 251.6 0.3 1.2 1 0 0 1 1 1 1 Piwi domain LAP1C PF05609.12 CDJ90208.1 - 0.0059 15.8 0.0 0.0072 15.5 0.0 1.3 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Beta-Casp PF10996.8 CDJ90208.1 - 0.13 12.6 0.1 2.4 8.5 0.0 2.9 4 0 0 4 4 4 0 Beta-Casp domain TIL PF01826.17 CDJ90209.1 - 2e-33 114.4 126.4 1.7e-10 41.0 16.5 9.9 10 1 1 11 11 11 6 Trypsin Inhibitor like cysteine rich domain Sod_Cu PF00080.20 CDJ90209.1 - 1.7e-10 41.2 0.0 3.2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) WAP PF00095.21 CDJ90209.1 - 9.3e-07 29.1 21.9 2.4e-05 24.6 10.6 12.8 13 4 0 13 13 13 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' Ly-6_related PF06579.12 CDJ90210.1 - 2.2e-43 147.5 0.6 2.7e-43 147.2 0.6 1.1 1 0 0 1 1 1 1 Caenorhabditis elegans ly-6-related protein QVR PF17064.5 CDJ90210.1 - 1.6 9.0 8.9 4.7e+02 1.1 8.9 3.1 1 1 0 1 1 1 0 Sleepless protein CPG4 PF15481.6 CDJ90211.1 - 0.0062 17.1 4.9 0.0062 17.1 4.9 2.1 1 1 0 1 1 1 1 Chondroitin proteoglycan 4 Wap1 PF16997.5 CDJ90211.1 - 0.01 15.0 0.3 0.015 14.4 0.3 1.1 1 0 0 1 1 1 0 Wap1 domain IF-2B PF01008.17 CDJ90212.1 - 1.7e-18 66.8 2.5 2.2e-17 63.2 0.0 2.5 2 1 1 3 3 3 2 Initiation factor 2 subunit family Ndc1_Nup PF09531.10 CDJ90212.1 - 5.1 5.7 7.5 6.5 5.3 7.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOBP PF15279.6 CDJ90212.1 - 7.5 7.1 15.7 12 6.4 15.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Plus-3 PF03126.18 CDJ90213.1 - 7.8e-29 100.4 0.1 2e-28 99.1 0.1 1.7 1 0 0 1 1 1 1 Plus-3 domain MARVEL PF01284.23 CDJ90214.1 - 5.8e-08 32.9 13.4 8.3e-08 32.4 13.4 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.12 CDJ90214.1 - 0.043 13.6 2.7 0.1 12.4 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF588) DUF1308 PF07000.11 CDJ90214.1 - 0.088 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) DUF4231 PF14015.6 CDJ90214.1 - 0.61 10.6 8.0 1.7 9.2 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF4118 PF13493.6 CDJ90214.1 - 3.4 7.5 10.1 0.19 11.5 0.9 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4118) SYF2 PF08231.12 CDJ90215.1 - 0.00094 19.6 0.2 0.0015 19.0 0.2 1.2 1 0 0 1 1 1 1 SYF2 splicing factor Auts2 PF15336.6 CDJ90215.1 - 0.0051 17.0 0.1 0.0051 17.0 0.1 1.8 1 1 0 1 1 1 1 Autism susceptibility gene 2 protein Rx_N PF18052.1 CDJ90215.1 - 0.015 15.5 1.0 0.028 14.7 1.0 1.4 1 0 0 1 1 1 0 Rx N-terminal domain HTH_26 PF13443.6 CDJ90217.1 - 0.0002 21.7 0.1 0.00039 20.8 0.1 1.5 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain MarR_2 PF12802.7 CDJ90217.1 - 0.0017 18.2 0.1 0.0036 17.2 0.1 1.6 1 0 0 1 1 1 1 MarR family HTH_Tnp_ISL3 PF13542.6 CDJ90217.1 - 0.0085 15.5 0.1 0.018 14.4 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_IclR PF09339.10 CDJ90217.1 - 0.016 15.0 0.1 0.028 14.2 0.1 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_24 PF13412.6 CDJ90217.1 - 0.018 14.6 0.1 0.032 13.8 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 CDJ90217.1 - 0.021 14.6 0.3 0.045 13.6 0.0 1.7 2 0 0 2 2 2 0 HTH DNA binding domain HTH_AsnC-type PF13404.6 CDJ90217.1 - 0.026 14.4 0.3 0.23 11.3 0.1 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain LacI PF00356.21 CDJ90217.1 - 0.032 14.0 2.4 0.068 13.0 0.4 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_32 PF13565.6 CDJ90217.1 - 0.036 14.7 0.5 0.036 14.7 0.5 2.0 2 0 0 2 2 2 0 Homeodomain-like domain DUF3602 PF12223.8 CDJ90217.1 - 0.037 14.6 1.7 0.056 14.0 1.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3602) HTH_3 PF01381.22 CDJ90217.1 - 0.047 13.8 0.0 0.081 13.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix HTH_6 PF01418.17 CDJ90217.1 - 0.048 13.6 1.5 0.24 11.4 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family DUF4572 PF15139.6 CDJ90217.1 - 0.07 13.0 0.1 0.12 12.2 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4572) RabGAP-TBC PF00566.18 CDJ90219.1 - 2.5e-27 96.0 3.7 3.7e-27 95.4 3.7 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PQQ_3 PF13570.6 CDJ90219.1 - 0.0019 18.6 0.0 0.013 15.9 0.0 2.1 2 0 0 2 2 2 1 PQQ-like domain Helitron_like_N PF14214.6 CDJ90221.1 - 4.8e-62 209.6 0.0 5.6e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus SseB_C PF14581.6 CDJ90221.1 - 0.15 12.2 0.0 2.1 8.5 0.0 2.1 2 0 0 2 2 2 0 SseB protein C-terminal domain PIF1 PF05970.14 CDJ90222.1 - 1.9e-28 99.7 0.0 2.4e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.15 CDJ90222.1 - 2.1e-05 24.6 0.0 3.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CDJ90222.1 - 3.3e-05 23.7 0.0 4.2e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ90222.1 - 0.0038 17.1 0.1 0.15 11.8 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 CDJ90222.1 - 0.038 14.3 0.0 0.055 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2791 PF10923.8 CDJ90222.1 - 0.041 12.7 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) AAA_16 PF13191.6 CDJ90222.1 - 0.053 13.9 0.0 0.079 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 CDJ90222.1 - 0.065 12.7 0.0 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.22 CDJ90222.1 - 0.085 12.0 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain T2SSE PF00437.20 CDJ90222.1 - 0.088 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 CDJ90222.1 - 0.11 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 CDJ90222.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 CDJ90222.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 CDJ90222.1 - 0.13 12.6 0.0 0.34 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CDJ90222.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Integrase_H2C2 PF17921.1 CDJ90223.1 - 3.9e-15 55.7 0.5 7.7e-15 54.7 0.2 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain MtN3_slv PF03083.16 CDJ90225.1 - 6e-50 167.2 16.9 2.5e-25 88.3 5.5 2.7 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 CDJ90225.1 - 0.017 14.9 0.3 0.017 14.9 0.3 4.2 3 1 1 4 4 4 0 PQ loop repeat LAB_N PF07578.11 CDJ90225.1 - 0.095 12.8 4.9 0.19 11.9 0.2 3.0 2 1 1 3 3 3 0 Lipid A Biosynthesis N-terminal domain TRIQK PF15168.6 CDJ90225.1 - 0.13 12.1 0.9 0.32 10.9 0.9 1.6 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family Capsule_synth PF05159.14 CDJ90228.1 - 0.024 14.1 1.5 0.028 13.9 1.5 1.2 1 0 0 1 1 1 0 Capsule polysaccharide biosynthesis protein eIF-4B PF06273.11 CDJ90228.1 - 0.53 9.3 8.9 0.59 9.1 8.9 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Endonuc_Holl PF10107.9 CDJ90228.1 - 0.71 9.7 7.0 0.91 9.4 7.0 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase YjbH PF06082.11 CDJ90228.1 - 1.7 7.4 3.8 1.7 7.4 3.8 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Activator_LAG-3 PF11498.8 CDJ90228.1 - 1.7 7.5 8.9 1.9 7.4 8.9 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DDRGK PF09756.9 CDJ90228.1 - 1.8 8.1 18.9 2.1 7.9 18.9 1.1 1 0 0 1 1 1 0 DDRGK domain EssA PF10661.9 CDJ90228.1 - 4.7 7.0 10.0 6.2 6.7 10.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA Radial_spoke_3 PF06098.11 CDJ90228.1 - 6.1 6.0 20.5 1.8 7.7 17.9 1.4 1 1 0 1 1 1 0 Radial spoke protein 3 DUF5401 PF17380.2 CDJ90228.1 - 7 4.6 22.5 8 4.4 22.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Patatin PF01734.22 CDJ90229.1 - 8.7e-12 45.6 1.2 3.2e-11 43.8 1.2 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase FIST PF08495.10 CDJ90229.1 - 0.11 12.5 0.0 1.3 9.0 0.0 2.2 1 1 0 1 1 1 0 FIST N domain FapA PF03961.13 CDJ90230.1 - 0.0056 15.3 2.2 0.047 12.3 0.4 2.0 2 0 0 2 2 2 1 Flagellar Assembly Protein A Metal_resist PF13801.6 CDJ90230.1 - 0.0073 16.5 1.8 0.37 11.0 0.0 2.5 2 0 0 2 2 2 1 Heavy-metal resistance Tmemb_cc2 PF10267.9 CDJ90230.1 - 0.022 14.0 9.6 0.009 15.2 3.5 2.3 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Rootletin PF15035.6 CDJ90230.1 - 0.031 14.3 12.4 0.058 13.4 4.5 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Fez1 PF06818.15 CDJ90230.1 - 0.039 14.4 10.6 0.075 13.5 10.6 1.4 1 1 0 1 1 1 0 Fez1 DUF2681 PF10883.8 CDJ90230.1 - 0.082 13.3 5.3 0.38 11.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF2570 PF10828.8 CDJ90230.1 - 0.11 12.4 5.8 0.49 10.2 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) SHE3 PF17078.5 CDJ90230.1 - 0.11 12.2 14.4 0.029 14.1 6.2 2.2 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 TMPIT PF07851.13 CDJ90230.1 - 0.28 10.4 7.0 0.13 11.5 2.6 2.0 2 0 0 2 2 2 0 TMPIT-like protein GAS PF13851.6 CDJ90230.1 - 0.74 9.1 17.3 0.061 12.7 9.9 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 CDJ90230.1 - 0.8 8.7 8.5 2 7.5 8.5 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Wtap PF17098.5 CDJ90230.1 - 1.3 9.0 13.7 1.6 8.7 6.5 2.6 2 0 0 2 2 2 0 WTAP/Mum2p family PCRF PF03462.18 CDJ90230.1 - 3.1 7.6 11.8 0.73 9.7 6.0 2.1 2 0 0 2 2 2 0 PCRF domain Prefoldin_2 PF01920.20 CDJ90230.1 - 5.1 7.1 16.1 0.16 11.9 7.5 2.5 2 1 0 2 2 2 0 Prefoldin subunit DUF948 PF06103.11 CDJ90230.1 - 7.8 6.8 8.1 1 9.6 0.6 2.8 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.15 CDJ90230.1 - 8.3 6.3 12.9 0.25 11.1 2.8 3.1 3 2 0 3 3 3 0 Septum formation initiator EzrA PF06160.12 CDJ90231.1 - 0.0028 15.9 7.1 0.0028 15.9 7.1 2.2 1 1 0 2 2 2 2 Septation ring formation regulator, EzrA She9_MDM33 PF05546.11 CDJ90231.1 - 0.011 15.5 4.8 0.011 15.5 4.8 3.8 1 1 3 4 4 3 0 She9 / Mdm33 family Sec8_exocyst PF04048.14 CDJ90231.1 - 0.02 14.8 23.0 0.4 10.6 0.5 4.0 1 1 3 4 4 4 0 Sec8 exocyst complex component specific domain HrpB7 PF09486.10 CDJ90231.1 - 0.048 14.0 0.9 0.048 14.0 0.9 3.7 1 1 3 4 4 4 0 Bacterial type III secretion protein (HrpB7) Spc7 PF08317.11 CDJ90231.1 - 0.093 11.6 46.4 0.031 13.2 15.9 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein TolA_bind_tri PF16331.5 CDJ90231.1 - 0.8 9.8 26.7 0.66 10.1 3.5 3.6 2 1 2 4 4 4 0 TolA binding protein trimerisation DUF1515 PF07439.11 CDJ90231.1 - 0.85 9.7 20.4 0.07 13.2 2.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) DUF4172 PF13776.6 CDJ90231.1 - 1.4 9.3 7.2 0.22 11.9 0.5 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4172) DUF1664 PF07889.12 CDJ90231.1 - 2.5 8.1 24.7 1.4 9.0 3.0 3.5 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Lebercilin PF15619.6 CDJ90231.1 - 2.8 7.5 46.6 0.12 12.0 16.8 3.1 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease ADIP PF11559.8 CDJ90231.1 - 4.2 7.4 40.9 0.036 14.2 14.3 3.8 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding COG5 PF10392.9 CDJ90231.1 - 4.8 7.4 14.5 0.49 10.6 7.6 2.4 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Laminin_II PF06009.12 CDJ90231.1 - 7.3 6.6 29.2 2.4 8.2 2.5 3.2 1 1 2 3 3 3 0 Laminin Domain II Prominin PF05478.11 CDJ90231.1 - 8.3 4.2 20.8 14 3.5 20.8 1.3 1 1 0 1 1 1 0 Prominin DUF3584 PF12128.8 CDJ90231.1 - 8.7 3.7 39.1 1 6.8 27.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 CDJ90231.1 - 8.8 6.4 8.9 8.9 6.4 1.5 3.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF745 PF05335.13 CDJ90231.1 - 9.7 5.9 32.7 0.65 9.7 6.6 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF745) KASH_CCD PF14662.6 CDJ90232.1 - 0.0028 17.5 48.2 0.29 10.9 12.0 4.1 1 1 3 4 4 4 3 Coiled-coil region of CCDC155 or KASH CCDC92 PF14916.6 CDJ90232.1 - 0.0087 15.8 0.7 0.0087 15.8 0.7 5.1 6 0 0 6 6 6 1 Coiled-coil domain of unknown function ApoO PF09769.9 CDJ90232.1 - 0.02 14.8 0.4 0.02 14.8 0.4 3.7 1 1 3 4 4 4 0 Apolipoprotein O Cnn_1N PF07989.11 CDJ90232.1 - 0.021 14.9 40.8 0.04 14.1 4.1 5.7 4 1 1 5 5 5 0 Centrosomin N-terminal motif 1 bZIP_1 PF00170.21 CDJ90232.1 - 0.029 14.5 1.2 0.029 14.5 1.2 7.1 5 2 1 7 7 6 0 bZIP transcription factor GAS PF13851.6 CDJ90232.1 - 0.09 12.1 48.6 0.013 14.8 13.1 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3502 PF12010.8 CDJ90232.1 - 0.18 12.5 0.2 0.18 12.5 0.2 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF3502) Fez1 PF06818.15 CDJ90232.1 - 0.22 11.9 45.3 1.7 9.1 5.8 3.3 1 1 2 3 3 3 0 Fez1 TolA_bind_tri PF16331.5 CDJ90232.1 - 0.23 11.5 21.6 0.39 10.8 0.1 6.0 2 1 5 7 7 7 0 TolA binding protein trimerisation AIP3 PF03915.13 CDJ90232.1 - 0.32 10.0 29.4 0.95 8.5 21.9 2.3 1 1 1 2 2 2 0 Actin interacting protein 3 FliJ PF02050.16 CDJ90232.1 - 0.48 10.7 32.9 0.12 12.6 8.5 4.5 1 1 4 5 5 5 0 Flagellar FliJ protein Baculo_PEP_C PF04513.12 CDJ90232.1 - 0.49 10.4 11.7 1.7 8.7 0.4 3.5 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus ZapB PF06005.12 CDJ90232.1 - 0.78 10.2 50.4 0.065 13.7 1.7 6.0 2 2 2 4 4 4 0 Cell division protein ZapB APG6_N PF17675.1 CDJ90232.1 - 3.2 8.3 53.6 7 7.2 21.2 3.8 1 1 1 3 3 3 0 Apg6 coiled-coil region Filament PF00038.21 CDJ90232.1 - 3.6 7.1 44.1 1.5 8.3 3.0 4.1 1 1 2 3 3 3 0 Intermediate filament protein Spc7 PF08317.11 CDJ90232.1 - 4.5 6.1 47.2 0.069 12.0 22.8 3.6 1 1 1 2 2 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 CDJ90232.1 - 7.1 6.7 51.7 6 7.0 1.4 5.4 1 1 2 4 4 3 0 TPR/MLP1/MLP2-like protein LPP PF04728.13 CDJ90232.1 - 8.4 6.9 16.7 20 5.7 1.6 5.5 4 2 1 5 5 5 0 Lipoprotein leucine-zipper UPF0242 PF06785.11 CDJ90232.1 - 9.4 6.3 46.6 0.13 12.4 12.6 4.2 1 1 2 3 3 2 0 Uncharacterised protein family (UPF0242) N-terminus Kinesin PF00225.23 CDJ90233.1 - 6.5e-90 301.4 1.1 1e-89 300.7 1.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ90233.1 - 4.4e-18 65.6 0.1 8.8e-18 64.7 0.1 1.5 1 0 0 1 1 1 1 Microtubule binding Neur_chan_memb PF02932.16 CDJ90234.1 - 1.4e-25 90.8 0.4 1.9e-25 90.3 0.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CDJ90234.1 - 7.2e-21 74.6 0.2 9.8e-21 74.2 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain RT_RNaseH_2 PF17919.1 CDJ90237.1 - 6e-32 109.7 0.0 2.8e-31 107.5 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ90237.1 - 1.3e-31 109.0 0.0 3.8e-31 107.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ90237.1 - 1.1e-20 74.2 0.0 2.3e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ90237.1 - 2.3e-17 62.8 0.1 6.7e-17 61.3 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 CDJ90237.1 - 6.5e-09 36.2 0.0 1.4e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ90237.1 - 2.5e-08 34.4 0.0 5.1e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ90237.1 - 0.0012 19.2 0.0 0.0029 17.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease eIF3g PF12353.8 CDJ90237.1 - 0.021 15.2 0.3 0.021 15.2 0.3 3.1 4 0 0 4 4 4 0 Eukaryotic translation initiation factor 3 subunit G Asp_protease PF09668.10 CDJ90237.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Mid2 PF04478.12 CDJ90237.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Peptidase_A17 PF05380.13 CDJ90238.1 - 1.1e-21 77.5 0.0 1.3e-21 77.3 0.0 1.0 1 0 0 1 1 1 1 Pao retrotransposon peptidase RNase_H PF00075.24 CDJ90238.1 - 0.098 12.8 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 RNase H FimH_man-bind PF09160.10 CDJ90239.1 - 0.076 12.7 0.0 0.093 12.4 0.0 1.2 1 0 0 1 1 1 0 FimH, mannose binding E2R135 PF11570.8 CDJ90239.1 - 0.18 12.1 0.0 0.25 11.6 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 Exo_endo_phos_2 PF14529.6 CDJ90240.1 - 8.7e-11 41.7 0.0 1.5e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ90240.1 - 1.6e-06 27.9 0.0 2.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MVP_shoulder PF11978.8 CDJ90240.1 - 0.15 12.1 0.3 6.5 6.8 0.1 2.4 2 0 0 2 2 2 0 Shoulder domain Pyrophosphatase PF00719.19 CDJ90242.1 - 3.8e-50 169.8 0.2 4.8e-50 169.5 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase V_ATPase_I PF01496.19 CDJ90243.1 - 3.4 5.4 6.5 16 3.3 6.5 2.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_L22e PF01776.17 CDJ90244.1 - 9.5e-45 151.5 1.8 1.3e-44 151.1 1.8 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family Diphthamide_syn PF01866.17 CDJ90245.1 - 9.3e-33 113.9 0.0 1.3e-32 113.5 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Collagen PF01391.18 CDJ90246.1 - 4.4e-21 74.4 69.1 1.9e+02 1.9 69.1 3.1 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Collagen PF01391.18 CDJ90247.1 - 1.1e-24 85.9 76.6 1.8e+04 -8.2 73.5 4.2 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ90247.1 - 5.4e-08 32.8 0.7 7e-08 32.4 0.7 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Diphthamide_syn PF01866.17 CDJ90248.1 - 3.4e-23 82.6 0.2 3.9e-23 82.3 0.2 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Diphthamide_syn PF01866.17 CDJ90249.1 - 0.06 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative diphthamide synthesis protein Asp PF00026.23 CDJ90252.1 - 3.6e-46 158.0 0.7 4.2e-46 157.8 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ90252.1 - 4.4e-14 53.1 0.6 2.3e-07 31.2 1.0 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp PF00026.23 CDJ90253.1 - 7.2e-36 124.2 0.7 8.9e-36 123.9 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ90253.1 - 6.7e-14 52.5 0.2 2.6e-08 34.3 0.6 2.2 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal DUF5641 PF18701.1 CDJ90254.1 - 1.2e-07 31.8 0.0 1.7e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5641) CAP PF00188.26 CDJ90256.1 - 6.2e-29 101.4 14.1 4.3e-16 59.9 3.5 2.3 2 0 0 2 2 2 2 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ90256.1 - 1e-05 25.8 0.7 0.015 15.6 0.2 2.8 2 1 0 2 2 2 2 Ancylostoma-associated secreted protein related Peptidase_C74 PF12387.8 CDJ90256.1 - 0.071 12.6 0.3 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 Pestivirus NS2 peptidase Toxin_12 PF07740.12 CDJ90256.1 - 0.27 11.9 18.2 3.1 8.6 5.4 2.6 2 0 0 2 2 2 0 Ion channel inhibitory toxin TPR_12 PF13424.6 CDJ90257.1 - 2.8e-25 88.4 3.5 5.1e-14 52.3 0.2 1.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ90257.1 - 1.7e-16 59.5 0.2 3e-09 36.4 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ90257.1 - 3.5e-08 32.9 0.2 0.0014 18.5 0.2 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ90257.1 - 1.2e-07 31.2 6.8 8.5e-05 22.2 1.0 2.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ90257.1 - 0.0034 17.5 0.5 3.5 8.1 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ90257.1 - 0.034 14.5 1.6 9.8 6.8 0.0 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ90257.1 - 0.053 13.7 2.4 1 9.7 0.3 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat CCDC50_N PF15295.6 CDJ90257.1 - 0.1 12.7 1.1 0.2 11.8 0.4 1.7 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus EF-hand_1 PF00036.32 CDJ90258.1 - 3.5e-27 91.9 12.1 2e-06 27.0 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ90258.1 - 1.2e-23 83.4 6.0 7e-13 48.8 1.3 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ90258.1 - 2.4e-22 76.9 8.0 3.6e-05 23.4 0.5 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CDJ90258.1 - 1.3e-18 65.6 10.0 9.2e-05 21.8 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CDJ90258.1 - 1e-13 50.9 10.9 6e-05 22.8 1.4 4.2 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ90258.1 - 3.3e-06 27.4 0.1 0.073 13.4 0.0 2.5 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CDJ90258.1 - 5.8e-06 26.2 4.7 0.06 13.3 0.3 3.8 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 CDJ90258.1 - 0.0089 16.0 6.1 9.4 6.1 0.2 3.8 1 1 2 4 4 4 2 Caleosin related protein EF-hand_9 PF14658.6 CDJ90258.1 - 0.012 15.9 0.2 0.18 12.1 0.1 2.6 3 0 0 3 3 3 0 EF-hand domain Toprim_2 PF13155.6 CDJ90258.1 - 0.15 12.5 0.1 3 8.3 0.0 2.2 1 1 0 2 2 2 0 Toprim-like Dockerin_1 PF00404.18 CDJ90258.1 - 0.18 12.1 1.9 3.8 7.8 0.6 3.1 2 1 2 4 4 4 0 Dockerin type I domain F-box PF00646.33 CDJ90259.1 - 7.2e-09 35.3 0.4 2.7e-08 33.5 0.6 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CDJ90259.1 - 7e-06 25.8 0.6 2e-05 24.4 0.6 1.8 1 0 0 1 1 1 1 F-box-like Nop PF01798.18 CDJ90260.1 - 3.1e-83 278.7 0.0 3.1e-83 278.7 0.0 1.5 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CDJ90260.1 - 1.3e-20 73.6 0.4 1.3e-20 73.6 0.4 2.6 2 0 0 2 2 2 1 NOP5NT (NUC127) domain GAGA_bind PF06217.12 CDJ90260.1 - 0.91 9.7 6.9 1.7 8.9 6.9 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family TMCO5 PF14992.6 CDJ90261.1 - 0.01 15.5 2.1 0.02 14.5 2.1 1.6 1 0 0 1 1 1 1 TMCO5 family Ferritin PF00210.24 CDJ90263.1 - 5.7e-38 130.0 1.8 6.6e-38 129.8 1.8 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 CDJ90263.1 - 0.0031 17.9 0.2 0.0042 17.5 0.2 1.3 1 1 0 1 1 1 1 Rubrerythrin DUF2004 PF09406.10 CDJ90263.1 - 0.018 15.4 0.3 0.2 12.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2004) BCS1_N PF08740.11 CDJ90263.1 - 0.034 14.1 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 BCS1 N terminal Laminin_EGF PF00053.24 CDJ90264.1 - 1.8e-109 357.7 258.5 1.4e-10 41.1 12.0 13.8 12 1 1 13 13 13 13 Laminin EGF domain Laminin_N PF00055.17 CDJ90264.1 - 5.8e-78 261.7 0.0 2.6e-77 259.6 0.0 2.3 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) PCRF PF03462.18 CDJ90264.1 - 1.3e-40 139.4 0.5 1.3e-40 139.4 0.5 6.4 3 2 3 6 6 6 1 PCRF domain RF-1 PF00472.20 CDJ90264.1 - 2.6e-23 82.2 0.1 2.6e-23 82.2 0.1 4.0 4 2 1 5 5 5 1 RF-1 domain Laminin_I PF06008.14 CDJ90264.1 - 0.00014 21.6 20.7 0.00014 21.6 20.7 3.9 2 1 2 4 4 4 1 Laminin Domain I F5_F8_type_C PF00754.25 CDJ90264.1 - 0.00082 19.5 0.0 0.0023 18.1 0.0 1.7 1 0 0 1 1 1 1 F5/8 type C domain ABC_membrane_2 PF06472.15 CDJ90265.1 - 1.4e-91 306.7 3.5 1.8e-91 306.3 3.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CDJ90265.1 - 1.4e-16 61.3 0.0 3.7e-16 59.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 CDJ90265.1 - 0.00015 21.3 0.0 0.66 9.4 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CDJ90265.1 - 0.0088 15.9 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CDJ90265.1 - 0.01 16.3 0.0 0.02 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CDJ90265.1 - 0.065 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 CDJ90265.1 - 0.073 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 CDJ90265.1 - 0.081 13.3 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_27 PF13514.6 CDJ90265.1 - 0.099 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cyto_heme_lyase PF01265.17 CDJ90265.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase ABC_membrane PF00664.23 CDJ90265.1 - 0.12 12.0 3.1 0.19 11.4 3.1 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region Methyltransf_21 PF05050.12 CDJ90266.1 - 2.2e-16 60.3 0.0 2.9e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase FkbM domain Thermopsin PF05317.11 CDJ90266.1 - 0.12 11.8 0.2 0.16 11.4 0.2 1.2 1 0 0 1 1 1 0 Thermopsin His_Phos_2 PF00328.22 CDJ90267.1 - 2.4e-09 37.0 0.0 1.2e-07 31.5 0.1 2.6 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.22 CDJ90267.1 - 0.0011 18.7 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ABC_membrane PF00664.23 CDJ90268.1 - 1.4e-37 129.9 8.6 1.6e-37 129.7 8.6 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_membrane PF00664.23 CDJ90269.1 - 1.3e-37 129.9 8.6 1.6e-37 129.7 8.6 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region HHH_3 PF12836.7 CDJ90270.1 - 1.3e-19 70.2 0.0 2.4e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif Tex_YqgF PF16921.5 CDJ90270.1 - 3.2e-11 43.8 0.0 5.4e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_7 PF14635.6 CDJ90270.1 - 7e-08 32.8 0.0 1.3e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_9 PF17674.1 CDJ90270.1 - 8.6e-06 26.6 0.2 2.5e-05 25.1 0.1 1.8 2 0 0 2 2 2 1 HHH domain S1 PF00575.23 CDJ90270.1 - 1.3e-05 25.4 0.2 4.4e-05 23.7 0.2 1.9 1 1 0 1 1 1 1 S1 RNA binding domain YqgF PF14639.6 CDJ90270.1 - 7.3e-05 22.6 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 Transposase_20 PF02371.16 CDJ90270.1 - 0.091 13.1 0.0 18 5.7 0.0 2.3 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family DUF4543 PF15076.6 CDJ90271.1 - 0.016 15.4 0.2 0.075 13.2 0.2 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) CD20 PF04103.15 CDJ90272.1 - 1.8e-07 31.4 13.5 1.8e-07 31.4 13.5 2.0 1 1 1 2 2 2 1 CD20-like family DUF1700 PF08006.11 CDJ90272.1 - 6.7 6.2 7.2 0.77 9.3 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Glyco_transf_92 PF01697.27 CDJ90274.1 - 2.7e-34 119.0 0.0 3.5e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 CDJ90274.1 - 0.041 14.4 0.0 0.092 13.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 BP28CT PF08146.12 CDJ90275.1 - 2.3e-18 66.5 0.0 9.7e-18 64.5 0.0 2.1 1 0 0 1 1 1 1 BP28CT (NUC211) domain Vac14_Fab1_bd PF12755.7 CDJ90275.1 - 0.005 17.4 0.0 2.1 9.0 0.0 3.0 1 1 1 2 2 2 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CDJ90275.1 - 0.037 14.5 0.3 0.77 10.3 0.0 3.4 2 1 1 3 3 3 0 HEAT-like repeat CDT1_C PF16679.5 CDJ90275.1 - 0.17 12.3 1.8 0.95 9.9 0.0 3.1 4 0 0 4 4 4 0 DNA replication factor Cdt1 C-terminal domain MIP PF00230.20 CDJ90278.1 - 6.9e-45 153.5 6.3 8.5e-45 153.2 6.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein Phage_holin_5_2 PF16079.5 CDJ90278.1 - 0.11 12.8 0.1 0.11 12.8 0.1 3.1 4 0 0 4 4 4 0 Phage holin family Hol44, in holin superfamily V 2TM PF13239.6 CDJ90278.1 - 0.12 12.7 3.2 3.5 8.0 0.1 2.5 2 0 0 2 2 2 0 2TM domain Polysacc_synt_C PF14667.6 CDJ90278.1 - 3.3 7.8 11.2 4.9 7.2 3.1 3.2 2 2 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Bax1-I PF01027.20 CDJ90278.1 - 8.3 6.2 18.3 0.52 10.1 6.7 2.6 2 1 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Sushi PF00084.20 CDJ90280.1 - 3.4e-79 261.3 53.0 6.8e-11 42.6 0.4 14.7 14 1 0 14 14 14 12 Sushi repeat (SCR repeat) HRM PF02793.22 CDJ90280.1 - 0.00047 20.4 41.2 0.11 12.8 1.3 8.3 9 1 0 9 9 9 4 Hormone receptor domain Sushi PF00084.20 CDJ90281.1 - 2.8e-25 88.7 6.3 9.5e-08 32.5 0.1 3.0 3 0 0 3 3 3 3 Sushi repeat (SCR repeat) HRM PF02793.22 CDJ90281.1 - 0.0086 16.3 4.7 6.4 7.2 0.1 3.2 3 0 0 3 3 3 3 Hormone receptor domain Neur_chan_LBD PF02931.23 CDJ90282.1 - 8.5e-11 41.7 1.8 1.3e-10 41.1 1.8 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain ShK PF01549.24 CDJ90282.1 - 9.4e-09 35.7 9.7 1.8e-08 34.7 9.7 1.5 1 0 0 1 1 1 1 ShK domain-like ResIII PF04851.15 CDJ90283.1 - 9.5e-19 68.0 0.6 2.3e-17 63.5 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit RIG-I_C-RD PF11648.8 CDJ90283.1 - 5.4e-18 65.3 1.7 1.3e-17 64.1 1.7 1.6 1 0 0 1 1 1 1 C-terminal domain of RIG-I Helicase_C PF00271.31 CDJ90283.1 - 7.2e-18 65.0 1.6 8.1e-17 61.6 0.2 3.3 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ90283.1 - 3.8e-16 59.4 0.2 3e-15 56.4 0.0 2.5 2 1 1 3 3 3 1 DEAD/DEAH box helicase RIG-I_C PF18119.1 CDJ90283.1 - 0.0045 17.0 0.2 0.0045 17.0 0.2 2.4 2 1 0 2 2 2 1 RIG-I receptor C-terminal domain AAA_22 PF13401.6 CDJ90283.1 - 0.025 14.8 0.0 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CDJ90283.1 - 0.064 13.6 0.4 0.48 10.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain UvrD-helicase PF00580.21 CDJ90283.1 - 0.1 12.1 0.4 3.5 7.1 0.0 2.7 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_11 PF13086.6 CDJ90283.1 - 0.13 12.0 4.5 0.25 11.1 0.1 2.7 2 1 1 3 3 3 0 AAA domain TPP_enzyme_N PF02776.18 CDJ90284.1 - 1e-47 162.0 0.3 2.1e-47 161.0 0.3 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CDJ90284.1 - 8.2e-27 93.9 0.0 7.6e-26 90.7 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CDJ90284.1 - 9.1e-20 70.8 0.1 3.1e-19 69.1 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 CDJ90284.1 - 0.083 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Cu-oxidase_4 PF02578.15 CDJ90284.1 - 0.12 11.9 0.5 11 5.5 0.0 2.5 3 0 0 3 3 3 0 Multi-copper polyphenol oxidoreductase laccase DUF3456 PF11938.8 CDJ90285.1 - 2.5e-12 47.6 6.0 5.2e-07 30.3 2.8 2.3 1 1 1 2 2 2 2 TLR4 regulator and MIR-interacting MSAP EGF_CA PF07645.15 CDJ90285.1 - 3.4e-09 36.8 12.4 3.4e-09 36.8 12.4 4.1 3 1 1 4 4 4 1 Calcium-binding EGF domain cEGF PF12662.7 CDJ90285.1 - 0.0012 18.7 18.5 0.026 14.5 0.3 4.0 3 0 0 3 3 3 2 Complement Clr-like EGF-like EGF PF00008.27 CDJ90285.1 - 0.0012 19.1 5.6 0.0012 19.1 5.6 4.1 3 2 0 3 3 3 2 EGF-like domain Plasmod_Pvs28 PF06247.11 CDJ90285.1 - 0.0013 19.0 11.0 0.0013 19.0 11.0 3.3 3 1 0 3 3 3 1 Pvs28 EGF domain hEGF PF12661.7 CDJ90285.1 - 0.0018 18.8 0.7 0.0018 18.8 0.7 4.6 5 1 0 5 5 5 2 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CDJ90285.1 - 0.0031 17.5 9.9 0.0031 17.5 9.9 4.0 4 0 0 4 4 4 1 MSP1 EGF domain 1 FXa_inhibition PF14670.6 CDJ90285.1 - 0.0036 17.5 8.4 0.0036 17.5 8.4 4.6 3 1 1 4 4 4 1 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 CDJ90285.1 - 0.0082 16.3 10.3 0.0082 16.3 10.3 3.9 3 1 0 3 3 3 1 EGF domain Laminin_EGF PF00053.24 CDJ90285.1 - 0.018 15.2 15.4 0.018 15.2 15.4 4.7 3 1 1 4 4 4 0 Laminin EGF domain Gpi16 PF04113.14 CDJ90286.1 - 1.1e-48 166.1 0.0 1.3e-48 165.9 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Peptidase_C2 PF00648.21 CDJ90287.1 - 2.5e-47 161.3 0.0 4.1e-47 160.6 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease MIT PF04212.18 CDJ90287.1 - 5.2e-21 74.5 13.0 1.5e-11 44.2 3.8 2.3 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain Calpain_III PF01067.22 CDJ90287.1 - 3.9e-13 49.8 0.5 2.7e-08 34.2 0.0 3.1 3 1 0 3 3 3 2 Calpain large subunit, domain III TPR_12 PF13424.6 CDJ90287.1 - 0.46 10.8 4.8 18 5.7 1.3 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ90287.1 - 0.6 9.8 4.4 3.7 7.3 1.0 3.2 3 0 0 3 3 3 0 TPR repeat TPR_1 PF00515.28 CDJ90287.1 - 1.2 9.1 9.3 0.26 11.2 1.9 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat CAF1A PF12253.8 CDJ90288.1 - 1.8e-23 82.5 8.0 1.8e-23 82.5 8.0 6.0 3 2 2 5 5 5 1 Chromatin assembly factor 1 subunit A Hamartin PF04388.12 CDJ90288.1 - 0.27 9.9 18.5 0.37 9.4 18.5 1.3 1 0 0 1 1 1 0 Hamartin protein DJ-1_PfpI PF01965.24 CDJ90290.1 - 6.2e-47 159.5 0.1 7.1e-47 159.3 0.1 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 CDJ90290.1 - 0.00096 18.8 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain MRP-L27 PF09809.9 CDJ90291.1 - 3.8e-11 42.8 0.3 4e-09 36.3 0.1 2.2 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L27 PorA PF11271.8 CDJ90291.1 - 0.13 11.6 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Porin PorA Mito_carr PF00153.27 CDJ90292.1 - 8e-63 208.4 3.8 2.1e-20 72.4 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Evr1_Alr PF04777.13 CDJ90293.1 - 2.7e-30 104.8 0.8 4.1e-30 104.2 0.8 1.2 1 0 0 1 1 1 1 Erv1 / Alr family LisH_2 PF16045.5 CDJ90293.1 - 0.054 12.5 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 LisH Brix PF04427.18 CDJ90295.1 - 2.5e-35 122.3 0.7 2.5e-35 122.3 0.7 1.7 2 0 0 2 2 2 1 Brix domain DUF1126 PF06565.12 CDJ90295.1 - 0.048 13.5 0.0 0.15 11.9 0.0 1.9 1 0 0 1 1 1 0 DUF1126 PH-like domain G-patch PF01585.23 CDJ90296.1 - 1.6e-17 63.1 3.9 4.2e-17 61.8 2.3 2.3 2 0 0 2 2 2 1 G-patch domain OCRE PF17780.1 CDJ90296.1 - 5.4e-16 58.3 10.9 5.4e-16 58.3 10.9 1.8 2 0 0 2 2 2 1 OCRE domain G-patch_2 PF12656.7 CDJ90296.1 - 1.2e-10 41.3 1.3 4.6e-10 39.4 1.3 2.1 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 CDJ90296.1 - 1.6e-08 34.3 0.0 0.0016 18.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 CDJ90296.1 - 4.3e-05 22.7 4.5 7.9e-05 21.9 4.5 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RSRP PF17069.5 CDJ90296.1 - 0.00073 19.2 19.6 0.00073 19.2 19.6 2.1 2 0 0 2 2 2 1 Arginine/Serine-Rich protein 1 LCD1 PF09798.9 CDJ90296.1 - 0.015 13.9 0.7 0.022 13.3 0.7 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein zf-C2H2_2 PF12756.7 CDJ90296.1 - 0.053 13.8 0.2 0.053 13.8 0.2 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF3597 PF12200.8 CDJ90296.1 - 1.4 9.5 11.0 0.81 10.2 8.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3597) Tim44 PF04280.15 CDJ90297.1 - 8.5e-42 142.7 2.7 1.2e-41 142.3 0.2 2.5 3 0 0 3 3 3 1 Tim44-like domain MIF4G PF02854.19 CDJ90297.1 - 0.032 13.9 2.0 0.079 12.6 2.0 1.6 1 0 0 1 1 1 0 MIF4G domain CHAD PF05235.14 CDJ90297.1 - 0.12 12.3 3.9 0.23 11.4 3.9 1.4 1 0 0 1 1 1 0 CHAD domain DUF1870 PF08965.10 CDJ90297.1 - 0.81 9.7 5.5 6.8 6.7 2.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1870) OmpH PF03938.14 CDJ90297.1 - 1.1 9.7 16.3 3 8.2 16.3 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MapZ_EC1 PF18041.1 CDJ90297.1 - 1.4 9.2 15.0 10 6.4 0.1 3.3 1 1 1 3 3 3 0 MapZ extracellular domain 1 Allexi_40kDa PF05549.11 CDJ90297.1 - 1.7 8.1 6.9 2.7 7.4 6.4 1.5 1 1 0 1 1 1 0 Allexivirus 40kDa protein Neur_chan_memb PF02932.16 CDJ90297.1 - 2 8.4 7.4 3.3 7.7 7.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3347 PF11827.8 CDJ90297.1 - 2.8 8.1 14.7 0.58 10.3 6.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) Med9 PF07544.13 CDJ90297.1 - 3.3 7.9 12.2 1.7 8.8 3.4 2.7 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DMPK_coil PF08826.10 CDJ90297.1 - 6.8 6.9 17.8 0.49 10.6 7.9 2.8 1 1 1 2 2 2 0 DMPK coiled coil domain like MnmE_helical PF12631.7 CDJ90297.1 - 9 6.4 9.9 6.1 7.0 7.6 1.8 2 0 0 2 2 2 0 MnmE helical domain Mad3_BUB1_I PF08311.12 CDJ90298.1 - 6.5e-20 71.4 0.3 1.2e-19 70.5 0.3 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 CorA PF01544.18 CDJ90298.1 - 0.19 11.0 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein RCC1 PF00415.18 CDJ90300.1 - 7.4e-13 48.9 2.2 1.1e-05 26.0 0.0 3.7 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ90300.1 - 1.1e-07 31.4 7.8 0.0028 17.4 3.5 2.7 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat zf-H2C2_2 PF13465.6 CDJ90300.1 - 0.0032 17.8 0.5 0.0032 17.8 0.5 4.3 6 0 0 6 6 6 1 Zinc-finger double domain Sgf11 PF08209.11 CDJ90300.1 - 0.048 13.2 0.1 0.048 13.2 0.1 3.1 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) DUF3046 PF11248.8 CDJ90300.1 - 0.06 13.7 0.1 0.71 10.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3046) zf-C2H2_2 PF12756.7 CDJ90300.1 - 0.45 10.9 15.2 0.55 10.6 3.1 3.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) LIM PF00412.22 CDJ90300.1 - 4 7.7 7.8 0.39 11.0 0.8 2.7 2 0 0 2 2 2 0 LIM domain DDE_Tnp_4 PF13359.6 CDJ90301.1 - 1.6e-16 60.3 0.0 3.9e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-C2H2_4 PF13894.6 CDJ90301.1 - 0.00099 19.8 16.0 0.022 15.6 1.5 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ90301.1 - 0.026 14.8 0.5 0.026 14.8 0.5 2.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CDJ90301.1 - 0.37 11.1 7.3 0.45 10.9 0.2 3.3 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-WRNIP1_ubi PF18279.1 CDJ90301.1 - 1.1 10.1 2.9 1.1 10.1 0.2 2.5 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-C2H2_2 PF12756.7 CDJ90301.1 - 1.1 9.6 4.9 12 6.3 0.5 3.0 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 CDJ90301.1 - 4.9 7.8 14.3 3.2 8.4 0.0 4.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type DDE_Tnp_4 PF13359.6 CDJ90302.1 - 5.1e-12 45.7 0.2 2e-11 43.8 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Transposase_1 PF01359.18 CDJ90302.1 - 0.00023 20.9 0.5 0.0013 18.5 0.0 2.2 2 0 0 2 2 2 1 Transposase (partial DDE domain) RecO_C PF02565.15 CDJ90302.1 - 0.049 13.4 0.0 7.6 6.3 0.0 2.6 2 0 0 2 2 2 0 Recombination protein O C terminal THAP PF05485.12 CDJ90302.1 - 0.38 11.7 3.2 18 6.3 0.1 3.6 4 0 0 4 4 4 0 THAP domain CAP PF00188.26 CDJ90303.1 - 1.1e-09 39.1 2.1 1.1e-09 39.1 2.1 1.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ90303.1 - 7.6e-05 23.0 1.1 0.00013 22.2 1.1 1.4 1 1 0 1 1 1 1 Ancylostoma-associated secreted protein related DDE_3 PF13358.6 CDJ90304.1 - 1.1e-06 28.5 0.0 1.6e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Exo_endo_phos PF03372.23 CDJ90304.1 - 0.025 14.1 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family CAP PF00188.26 CDJ90305.1 - 4.6e-09 37.2 0.1 7.6e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ90305.1 - 5.7e-07 29.8 1.8 1.4e-06 28.6 1.8 1.6 1 1 0 1 1 1 1 Ancylostoma-associated secreted protein related MFS_1_like PF12832.7 CDJ90306.1 - 7.3e-07 28.4 0.1 7.3e-07 28.4 0.1 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 CDJ90306.1 - 0.00077 18.5 2.7 0.0009 18.3 2.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PTS_EIIC_2 PF13303.6 CDJ90306.1 - 0.0086 15.1 0.4 0.0099 14.9 0.4 1.1 1 0 0 1 1 1 1 Phosphotransferase system, EIIC Shisa PF13908.6 CDJ90307.1 - 3.5e-05 24.1 0.9 5.5e-05 23.5 0.9 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator SUR7 PF06687.12 CDJ90307.1 - 7.8e-05 22.4 3.0 9.8e-05 22.1 3.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family EphA2_TM PF14575.6 CDJ90307.1 - 0.00069 20.4 0.2 0.0014 19.4 0.2 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain ETRAMP PF09716.10 CDJ90307.1 - 0.016 15.3 2.0 0.029 14.4 0.4 2.2 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) FAM163 PF15069.6 CDJ90307.1 - 0.019 15.4 2.3 0.032 14.7 2.3 1.4 1 0 0 1 1 1 0 FAM163 family TMEM154 PF15102.6 CDJ90307.1 - 0.021 14.7 0.1 0.034 14.0 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family TMEM52 PF14979.6 CDJ90307.1 - 0.022 14.7 4.6 0.043 13.7 4.6 1.5 1 0 0 1 1 1 0 Transmembrane 52 Cadherin_C_2 PF16492.5 CDJ90307.1 - 0.031 15.0 0.2 0.083 13.6 0.2 1.7 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Claudin_2 PF13903.6 CDJ90307.1 - 0.032 14.0 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction TRP PF06011.12 CDJ90307.1 - 0.034 12.9 0.0 0.041 12.6 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DAG1 PF05454.11 CDJ90307.1 - 0.035 13.5 0.3 0.049 13.0 0.3 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF4446 PF14584.6 CDJ90307.1 - 0.055 13.5 0.1 0.12 12.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF4834 PF16118.5 CDJ90307.1 - 0.17 12.9 0.0 0.36 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Sigma_reg_N PF13800.6 CDJ90307.1 - 0.26 11.6 0.3 0.57 10.5 0.3 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal EVC2_like PF12297.8 CDJ90307.1 - 0.27 9.9 0.0 0.37 9.4 0.0 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Prominin PF05478.11 CDJ90307.1 - 0.65 7.9 6.9 0.88 7.4 6.9 1.1 1 0 0 1 1 1 0 Prominin LRRC37AB_C PF14914.6 CDJ90307.1 - 5 7.0 7.3 9.3 6.1 7.3 1.5 1 1 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain AnfG_VnfG PF03139.15 CDJ90310.1 - 0.038 14.1 0.6 0.092 12.8 0.4 1.7 1 1 1 2 2 2 0 Vanadium/alternative nitrogenase delta subunit RNA_pol_Rpb1_5 PF04998.17 CDJ90310.1 - 0.18 11.2 0.5 0.23 10.9 0.5 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Thioredoxin PF00085.20 CDJ90311.1 - 2.2e-11 43.7 0.0 6e-11 42.3 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin DUF953 PF06110.11 CDJ90311.1 - 0.021 14.4 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) AhpC-TSA PF00578.21 CDJ90311.1 - 0.045 13.7 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_8 PF13905.6 CDJ90311.1 - 0.14 12.5 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Aldo_ket_red PF00248.21 CDJ90312.1 - 2.1e-46 158.5 0.0 2.6e-45 154.9 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family ssDBP_DBD PF18361.1 CDJ90312.1 - 0.0084 16.2 0.0 0.065 13.4 0.0 2.2 2 1 0 2 2 2 1 Single stranded DNA-binding protein ss DNA binding domain HLH PF00010.26 CDJ90313.1 - 1.9e-12 46.9 0.0 2.9e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain IPT PF01745.16 CDJ90313.1 - 0.13 11.6 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Isopentenyl transferase IPP-2 PF04979.14 CDJ90314.1 - 1.8e-06 28.7 0.4 2.5e-06 28.3 0.4 1.2 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) TFIIF_beta_N PF17683.1 CDJ90314.1 - 0.063 14.0 0.2 0.089 13.5 0.2 1.3 1 0 0 1 1 1 0 TFIIF, beta subunit N-terminus NB-ARC PF00931.22 CDJ90315.1 - 2.2e-29 102.4 0.0 3.2e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 CDJ90315.1 - 0.00029 20.8 0.2 0.0021 18.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain CARD PF00619.21 CDJ90315.1 - 0.0003 20.7 0.1 0.0018 18.2 0.0 2.4 2 0 0 2 2 2 1 Caspase recruitment domain AAA_16 PF13191.6 CDJ90315.1 - 0.00042 20.7 0.1 0.0031 17.9 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CDJ90315.1 - 0.034 14.6 0.0 0.11 12.9 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CDJ90315.1 - 0.04 14.5 0.0 0.86 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 CDJ90315.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MukB PF04310.12 CDJ90315.1 - 0.06 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 MukB N-terminal DUF815 PF05673.13 CDJ90315.1 - 0.069 12.3 0.0 0.2 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 CDJ90315.1 - 0.094 13.0 0.1 0.43 10.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain Myb_DNA-bind_4 PF13837.6 CDJ90316.1 - 0.035 14.5 0.0 0.072 13.5 0.0 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF836 PF05768.14 CDJ90317.1 - 0.018 15.4 0.4 0.044 14.2 0.4 1.7 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) CUB PF00431.20 CDJ90318.1 - 7e-15 55.3 0.3 5.4e-11 42.8 0.0 4.1 5 1 0 5 5 5 2 CUB domain ECR1_N PF14382.6 CDJ90318.1 - 0.03 14.1 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region CBM_20 PF00686.19 CDJ90318.1 - 0.05 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Starch binding domain 7tm_1 PF00001.21 CDJ90319.1 - 8.1e-44 149.9 7.3 8.1e-44 149.9 7.3 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CDJ90319.1 - 2.9e-09 37.0 6.5 4.5e-09 36.3 6.2 1.5 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 CDJ90319.1 - 5.7e-08 32.4 5.1 8.6e-08 31.9 5.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 CDJ90319.1 - 0.0073 16.1 2.3 0.0073 16.1 2.3 1.4 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srbc PF10316.9 CDJ90319.1 - 0.011 15.3 8.0 0.015 14.8 8.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srbc RVT_1 PF00078.27 CDJ90320.1 - 5.7e-44 150.3 0.0 1.1e-43 149.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_1 PF07690.16 CDJ90320.1 - 4.3e-14 52.2 3.3 6.4e-14 51.6 3.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 CDJ90320.1 - 2.2e-07 30.5 6.7 3e-07 30.1 6.7 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Hydrolase_2 PF07486.12 CDJ90320.1 - 0.0032 18.3 2.3 2.4 9.1 0.2 2.8 2 0 0 2 2 2 2 Cell Wall Hydrolase UPF0242 PF06785.11 CDJ90320.1 - 0.013 15.6 0.2 0.043 13.9 0.2 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Sugar_tr PF00083.24 CDJ90320.1 - 0.015 14.2 3.0 0.035 13.0 3.0 1.5 1 1 0 1 1 1 0 Sugar (and other) transporter ATG22 PF11700.8 CDJ90320.1 - 0.13 10.9 4.5 0.21 10.2 4.5 1.2 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like VEG PF06257.11 CDJ90320.1 - 0.18 11.8 0.1 3.6 7.7 0.0 2.6 2 0 0 2 2 2 0 Biofilm formation stimulator VEG Snapin_Pallidin PF14712.6 CDJ90320.1 - 8.8 6.8 7.8 1.7 9.1 2.8 2.5 3 0 0 3 3 3 0 Snapin/Pallidin MFS_1 PF07690.16 CDJ90321.1 - 8.4e-26 90.7 17.4 1.1e-25 90.3 17.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ90321.1 - 0.0027 16.6 18.0 0.0044 16.0 18.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter DUF4131 PF13567.6 CDJ90321.1 - 0.017 14.8 1.8 0.017 14.8 1.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Yippee-Mis18 PF03226.14 CDJ90321.1 - 0.11 12.8 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TRIQK PF15168.6 CDJ90321.1 - 0.14 12.1 0.2 0.32 10.9 0.2 1.6 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family LacY_symp PF01306.19 CDJ90321.1 - 0.43 9.3 12.1 0.66 8.7 12.1 1.2 1 0 0 1 1 1 0 LacY proton/sugar symporter UCR_Fe-S_N PF10399.9 CDJ90321.1 - 7.5 6.0 10.0 0.71 9.3 2.2 2.4 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Pkinase PF00069.25 CDJ90322.1 - 1.7e-39 135.8 0.0 2.2e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ90322.1 - 3.1e-20 72.5 0.1 4.3e-20 72.1 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ90322.1 - 7.4e-07 28.8 0.0 1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDJ90322.1 - 0.0035 16.7 0.4 0.005 16.2 0.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ90322.1 - 0.092 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ90322.1 - 0.1 11.4 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Plasmod_dom_1 PF09715.10 CDJ90323.1 - 0.13 12.3 0.1 7.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) Spo12 PF05032.12 CDJ90324.1 - 0.0014 18.5 1.6 0.0025 17.7 0.3 2.1 3 0 0 3 3 3 1 Spo12 family tRNA_Me_trans PF03054.16 CDJ90325.1 - 2.9e-115 384.9 0.0 3.3e-115 384.7 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 CDJ90325.1 - 8.2e-06 25.5 0.0 9.8e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.17 CDJ90325.1 - 1.5e-05 24.3 0.0 0.00065 18.9 0.0 2.2 2 0 0 2 2 2 2 NAD synthase ATP_bind_3 PF01171.20 CDJ90325.1 - 0.0019 18.0 0.0 0.008 16.0 0.0 1.9 1 1 0 1 1 1 1 PP-loop family F-box PF00646.33 CDJ90326.1 - 1.9e-08 34.0 0.2 6.8e-08 32.2 0.2 2.0 1 0 0 1 1 1 1 F-box domain STI1 PF17830.1 CDJ90327.1 - 7.8e-14 51.4 4.2 1.3e-13 50.6 4.2 1.3 1 0 0 1 1 1 1 STI1 domain eIF3_subunit PF08597.10 CDJ90327.1 - 0.042 13.7 1.5 0.047 13.6 1.5 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit RVT_1 PF00078.27 CDJ90329.1 - 8.4e-18 64.7 0.0 9e-18 64.6 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPPK_C PF12555.8 CDJ90330.1 - 0.046 13.8 0.3 0.075 13.1 0.3 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Ion_trans_2 PF07885.16 CDJ90331.1 - 1.6e-20 72.8 22.1 5.7e-11 42.2 2.4 3.2 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CDJ90331.1 - 0.0045 16.2 15.5 0.044 13.0 1.8 2.3 2 0 0 2 2 2 2 Ion transport protein SCVP PF17619.2 CDJ90332.1 - 6.9e-14 52.5 0.2 8.8e-14 52.1 0.2 1.1 1 0 0 1 1 1 1 Secreted clade V proteins SapB_1 PF05184.15 CDJ90332.1 - 0.077 13.0 0.2 7.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Saposin-like type B, region 1 SCVP PF17619.2 CDJ90333.1 - 3.1e-12 47.2 0.4 4.4e-12 46.7 0.4 1.2 1 0 0 1 1 1 1 Secreted clade V proteins DUF236 PF03057.14 CDJ90335.1 - 3.3e-45 151.7 30.4 6.4e-16 58.0 0.5 4.3 4 1 0 4 4 4 3 DUF236 repeat DUF3857 PF12969.7 CDJ90335.1 - 0.0037 17.4 0.0 7.8 6.5 0.0 3.0 3 0 0 3 3 3 2 Domain of Unknown Function with PDB structure (DUF3857) CAP_N PF01213.19 CDJ90335.1 - 8.3 5.8 14.7 11 5.4 10.3 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF236 PF03057.14 CDJ90336.1 - 3.2e-123 401.2 73.3 5.9e-17 61.3 1.5 8.3 8 0 0 8 8 8 8 DUF236 repeat MAP17 PF15807.5 CDJ90336.1 - 0.011 16.0 0.1 0.017 15.4 0.1 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 eIF3g PF12353.8 CDJ90339.1 - 9.3e-32 110.1 3.3 9.3e-32 110.1 3.3 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 CDJ90339.1 - 8.5e-20 70.4 0.0 1.8e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 CDJ90339.1 - 0.0026 18.0 3.2 3.2 8.0 0.0 3.5 3 1 1 4 4 4 2 Cytosolic domain of 10TM putative phosphate transporter CDV3 PF15359.6 CDJ90339.1 - 0.035 14.6 1.0 0.071 13.6 1.0 1.6 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 Nup35_RRM_2 PF14605.6 CDJ90339.1 - 0.11 12.5 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCHC PF00098.23 CDJ90339.1 - 0.22 11.7 6.1 0.39 10.9 6.1 1.4 1 0 0 1 1 1 0 Zinc knuckle hDGE_amylase PF14701.6 CDJ90340.1 - 1.7e-148 495.4 0.3 2.5e-148 494.9 0.3 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 CDJ90340.1 - 3.3e-128 427.9 0.0 4.5e-128 427.4 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 CDJ90340.1 - 5.3e-69 232.7 0.0 7.9e-69 232.1 0.0 1.3 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 CDJ90340.1 - 8.4e-07 29.0 0.0 1.7e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 CDJ90340.1 - 0.0068 16.0 0.2 0.0068 16.0 0.2 2.3 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Y_phosphatase PF00102.27 CDJ90341.1 - 4.6e-71 239.1 0.0 5.6e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ90341.1 - 5.7e-05 22.9 0.1 0.00065 19.5 0.1 2.3 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDJ90341.1 - 0.011 15.8 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Exo_endo_phos PF03372.23 CDJ90341.1 - 0.032 13.8 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF3502 PF12010.8 CDJ90341.1 - 0.075 13.7 0.2 0.36 11.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3502) Y_phosphatase2 PF03162.13 CDJ90341.1 - 0.12 12.0 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Elf1 PF05129.13 CDJ90342.1 - 7.1e-32 109.3 1.9 7.9e-32 109.1 1.9 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.6 CDJ90342.1 - 0.062 13.7 2.3 0.077 13.4 2.3 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar DpnI PF06044.12 CDJ90342.1 - 0.073 12.7 1.3 0.09 12.4 1.3 1.1 1 0 0 1 1 1 0 Dam-replacing family Cys_rich_CPXG PF14255.6 CDJ90342.1 - 1.7 8.6 7.0 4.1 7.4 4.5 2.1 1 1 1 2 2 2 0 Cysteine-rich CPXCG Ribosomal_L27 PF01016.19 CDJ90343.1 - 2.5e-06 27.4 0.0 3.7e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein PDZ PF00595.24 CDJ90344.1 - 2.8e-20 72.5 0.1 4.1e-20 71.9 0.1 1.3 1 0 0 1 1 1 1 PDZ domain L27 PF02828.16 CDJ90344.1 - 5.6e-19 67.6 0.0 1.8e-18 66.0 0.0 1.8 2 0 0 2 2 2 1 L27 domain PDZ_6 PF17820.1 CDJ90344.1 - 1.7e-12 47.0 0.3 3.7e-12 45.9 0.3 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ90344.1 - 0.0096 16.2 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain DUF2057 PF09829.9 CDJ90344.1 - 0.21 11.8 0.0 3.2 7.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) TPR_12 PF13424.6 CDJ90345.1 - 7.5e-20 71.0 6.2 1.3e-06 28.6 0.1 4.9 4 1 0 4 4 4 3 Tetratricopeptide repeat Fe-S_biosyn PF01521.20 CDJ90345.1 - 2.6e-14 53.3 0.0 8.2e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis TPR_2 PF07719.17 CDJ90345.1 - 7.7e-14 50.6 7.2 0.0004 20.3 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ90345.1 - 3.3e-12 45.9 10.9 0.0014 18.5 0.0 6.2 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ90345.1 - 1.2e-10 40.7 8.0 0.033 14.4 0.1 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ90345.1 - 3.3e-09 36.2 6.7 0.0004 20.1 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ90345.1 - 2.9e-08 33.9 1.4 0.45 11.5 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ90345.1 - 2.4e-07 31.1 1.9 0.0077 16.7 0.0 4.5 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ90345.1 - 2.8e-07 31.1 0.1 0.91 10.2 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ90345.1 - 5.8e-06 26.6 0.8 0.13 12.9 0.0 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CDJ90345.1 - 1.2e-05 24.8 0.4 0.00076 18.9 0.1 2.5 2 1 0 2 2 2 1 MalT-like TPR region TPR_7 PF13176.6 CDJ90345.1 - 2.8e-05 23.8 9.4 0.068 13.2 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat RPN7 PF10602.9 CDJ90345.1 - 0.00013 21.7 1.0 0.00046 20.0 0.2 2.3 2 1 0 2 2 2 1 26S proteasome subunit RPN7 TPR_4 PF07721.14 CDJ90345.1 - 0.00023 21.5 0.0 0.22 12.2 0.0 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ90345.1 - 0.00025 21.2 1.0 7.2 7.2 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ90345.1 - 0.0012 18.5 0.2 0.48 10.2 0.0 3.8 3 0 0 3 3 3 1 TPR repeat ANAPC3 PF12895.7 CDJ90345.1 - 0.0068 16.6 0.7 6.8 7.0 0.1 3.2 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Mad3_BUB1_I PF08311.12 CDJ90345.1 - 0.044 13.8 1.4 8.7 6.4 0.0 3.8 2 2 1 3 3 3 0 Mad3/BUB1 homology region 1 TPR_3 PF07720.12 CDJ90345.1 - 0.11 12.5 1.7 24 5.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat CRAL_TRIO PF00650.20 CDJ90346.1 - 1.2e-20 73.8 0.0 1.7e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain DUF772 PF05598.11 CDJ90346.1 - 0.028 14.4 0.1 0.065 13.3 0.1 1.6 1 0 0 1 1 1 0 Transposase domain (DUF772) GOLD_2 PF13897.6 CDJ90346.1 - 0.043 14.3 0.6 0.47 10.9 0.1 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking DMAP1 PF05499.12 CDJ90347.1 - 0.25 11.2 0.1 0.25 11.2 0.1 2.1 2 0 0 2 2 2 0 DNA methyltransferase 1-associated protein 1 (DMAP1) FHA PF00498.26 CDJ90348.1 - 2.2e-07 31.1 0.8 4.8e-07 30.0 0.1 2.0 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 CDJ90348.1 - 3.3e-05 24.1 0.1 0.00019 21.7 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Ribosomal_L44 PF00935.19 CDJ90349.1 - 5.6e-36 122.9 15.6 7.4e-36 122.5 15.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Cathelicidins PF00666.17 CDJ90349.1 - 0.55 10.6 5.1 0.088 13.1 1.6 1.5 2 0 0 2 2 2 0 Cathelicidin PIF1 PF05970.14 CDJ90350.1 - 1.2e-95 320.8 0.0 1.5e-95 320.5 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CDJ90350.1 - 1.1e-09 38.3 0.0 2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CDJ90350.1 - 1.3e-05 25.1 0.1 0.09 12.5 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 CDJ90350.1 - 4.8e-05 23.7 0.0 0.00078 19.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 CDJ90350.1 - 0.00039 20.5 0.0 0.00076 19.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Herpes_Helicase PF02689.14 CDJ90350.1 - 0.0004 18.5 0.0 0.00073 17.6 0.0 1.3 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 CDJ90350.1 - 0.0015 18.3 0.0 0.0039 17.0 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_14 PF13173.6 CDJ90350.1 - 0.014 15.4 0.0 0.083 12.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 CDJ90350.1 - 0.016 14.5 0.1 2.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 CDJ90350.1 - 0.079 13.3 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain 4HPAD_g_N PF18671.1 CDJ90350.1 - 0.081 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal IstB_IS21 PF01695.17 CDJ90350.1 - 0.12 12.1 0.2 0.31 10.7 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Helitron_like_N PF14214.6 CDJ90351.1 - 5.3e-60 202.9 0.0 5.3e-60 202.9 0.0 1.9 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Asp PF00026.23 CDJ90352.1 - 4.7e-77 259.5 0.8 5.4e-77 259.3 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ90352.1 - 3.8e-17 63.1 1.6 2.6e-14 53.8 1.6 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 CDJ90353.1 - 1e-76 258.4 3.2 1.2e-76 258.1 3.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ90353.1 - 1.5e-16 61.2 2.3 4.1e-08 33.7 1.5 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Helicase_C_2 PF13307.6 CDJ90357.1 - 1.3e-50 171.9 0.1 2.8e-50 170.8 0.1 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 CDJ90357.1 - 5.3e-06 26.2 0.0 1.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 Rad60-SLD_2 PF13881.6 CDJ90358.1 - 6.8e-29 100.2 0.1 7.7e-29 100.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CDJ90358.1 - 4.7e-05 23.1 0.0 0.00012 21.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin family GbpA_2 PF18416.1 CDJ90358.1 - 0.044 14.1 0.0 0.092 13.0 0.0 1.5 2 0 0 2 2 2 0 N-acetylglucosamine binding protein domain 2 DUF2407 PF10302.9 CDJ90358.1 - 0.063 13.8 0.0 0.15 12.7 0.0 1.6 1 1 0 2 2 2 0 DUF2407 ubiquitin-like domain PH_TFIIH PF08567.11 CDJ90358.1 - 0.14 12.5 0.1 0.79 10.1 0.1 1.9 2 0 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain WD40 PF00400.32 CDJ90359.1 - 8.2e-34 115.1 16.3 2e-06 28.4 0.2 7.4 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ90359.1 - 3e-09 37.1 0.1 0.028 14.7 0.0 5.0 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ90359.1 - 4.4e-08 32.5 0.3 0.0034 16.4 0.0 3.4 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CDJ90359.1 - 0.001 18.5 0.1 0.0023 17.3 0.0 1.5 1 1 1 2 2 2 2 WD40-like domain Nbas_N PF15492.6 CDJ90359.1 - 0.015 14.6 0.1 1.1 8.5 0.0 2.9 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 CDJ90359.1 - 0.017 13.8 0.0 0.037 12.7 0.0 1.6 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CDJ90359.1 - 0.11 11.3 0.1 1.5 7.4 0.0 2.2 1 1 2 3 3 3 0 Nup133 N terminal like BPL_LplA_LipB PF03099.19 CDJ90360.1 - 0.00017 21.5 0.0 0.00056 19.8 0.0 1.9 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HTH_26 PF13443.6 CDJ90361.1 - 0.00018 21.9 0.1 0.0005 20.4 0.1 1.8 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_IclR PF09339.10 CDJ90361.1 - 0.0032 17.2 0.1 0.0059 16.4 0.1 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 CDJ90361.1 - 0.0093 15.8 0.1 0.02 14.8 0.1 1.5 1 0 0 1 1 1 1 MarR family TraI PF07057.11 CDJ90361.1 - 0.011 15.9 0.2 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 DNA helicase TraI HTH_Tnp_ISL3 PF13542.6 CDJ90361.1 - 0.028 13.8 0.1 0.07 12.6 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.6 CDJ90361.1 - 0.033 13.7 0.2 0.073 12.6 0.0 1.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF3602 PF12223.8 CDJ90361.1 - 0.034 14.8 0.2 0.087 13.4 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) CENP-B_N PF04218.13 CDJ90361.1 - 0.037 13.7 0.0 0.091 12.4 0.0 1.8 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain DUF771 PF05595.11 CDJ90361.1 - 0.038 13.9 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF771) LacI PF00356.21 CDJ90361.1 - 0.046 13.5 0.3 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_3 PF01381.22 CDJ90361.1 - 0.072 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix Asp PF00026.23 CDJ90362.1 - 5.8e-38 131.1 1.0 7.2e-38 130.8 1.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ90362.1 - 1.3e-12 48.3 6.1 6.8e-12 46.0 6.1 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal DUF3657 PF12394.8 CDJ90362.1 - 0.094 13.3 0.5 0.28 11.8 0.1 1.9 2 0 0 2 2 2 0 Protein FAM135 Nuc_sug_transp PF04142.15 CDJ90364.1 - 6.7e-112 373.7 21.4 7.6e-112 373.5 21.4 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CDJ90364.1 - 6.1e-07 29.7 32.5 2.6e-06 27.7 5.7 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CDJ90364.1 - 3.1e-05 23.3 16.8 5.7e-05 22.5 16.8 1.4 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 CDJ90364.1 - 0.0034 16.6 4.1 0.0034 16.6 4.1 2.7 1 1 0 2 2 2 1 Purine nucleobase transmembrane transport COX14 PF14880.6 CDJ90364.1 - 0.11 12.4 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 Cytochrome oxidase c assembly FUSC-like PF12805.7 CDJ90364.1 - 0.73 8.9 7.2 0.7 8.9 3.9 2.3 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS HOOK PF05622.12 CDJ90365.1 - 2.8e-23 82.0 54.1 2.8e-23 82.0 54.1 3.9 1 1 3 4 4 4 2 HOOK protein GAS PF13851.6 CDJ90365.1 - 3.2e-05 23.4 16.4 3.2e-05 23.4 16.4 8.5 3 3 4 8 8 8 6 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 CDJ90365.1 - 0.0076 16.5 18.8 0.0076 16.5 18.8 8.4 1 1 6 7 7 7 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 CDJ90365.1 - 0.014 14.3 154.1 0.66 8.8 23.3 8.1 3 2 5 8 8 8 0 Spc7 kinetochore protein Cep57_CLD_2 PF14197.6 CDJ90365.1 - 0.02 15.0 1.4 0.02 15.0 1.4 14.3 4 4 7 12 12 12 0 Centrosome localisation domain of PPC89 DUF5403 PF17395.2 CDJ90365.1 - 0.22 11.8 0.8 2.5 8.5 0.1 3.3 2 0 0 2 2 2 0 Family of unknown function (DUF5403) DUF2362 PF10154.9 CDJ90366.1 - 1.4e-104 350.8 2.0 5.4e-104 348.9 2.0 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) TTL PF03133.15 CDJ90366.1 - 1e-82 277.6 0.0 3.2e-82 276.0 0.0 1.8 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CDJ90366.1 - 6.3e-06 25.6 0.0 0.0014 18.0 0.0 2.4 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CDJ90366.1 - 0.00028 20.3 0.0 0.17 11.1 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp Filament PF00038.21 CDJ90366.1 - 0.019 14.5 0.7 0.019 14.5 0.7 1.8 2 0 0 2 2 2 0 Intermediate filament protein DUF4055 PF13264.6 CDJ90367.1 - 0.22 11.7 1.5 2.9 8.0 1.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4055) Metal_CEHH PF14455.6 CDJ90367.1 - 3.1 7.4 8.2 39 3.8 0.1 4.0 1 1 3 4 4 4 0 Predicted metal binding domain Pox_F15 PF04596.12 CDJ90368.1 - 0.062 13.1 0.0 13 5.5 0.0 2.8 1 1 3 4 4 4 0 Poxvirus protein F15 Toxin_21 PF08091.11 CDJ90368.1 - 0.53 10.3 1.7 20 5.2 0.1 3.4 3 1 1 4 4 4 0 Spider insecticidal peptide DUF5635 PF18685.1 CDJ90368.1 - 0.68 9.9 1.9 17 5.5 0.0 2.8 2 2 1 3 3 3 0 Family of unknown function (DUF5635) DUF865 PF05906.11 CDJ90368.1 - 1 9.2 6.1 1.2e+02 2.6 0.2 4.1 4 0 0 4 4 4 0 Herpesvirus-7 repeat of unknown function (DUF865) Phlebovirus_G2 PF07245.11 CDJ90368.1 - 2 6.8 5.3 6.6 5.1 0.6 2.8 1 1 3 4 4 4 0 Phlebovirus glycoprotein G2 SPRY PF00622.28 CDJ90369.1 - 6.1e-15 55.4 0.1 1.4e-14 54.3 0.1 1.6 1 0 0 1 1 1 1 SPRY domain zf-B_box PF00643.24 CDJ90369.1 - 2.9e-09 36.9 29.6 8.7e-06 25.8 10.2 3.9 3 0 0 3 3 3 2 B-box zinc finger zf-C3HC4_4 PF15227.6 CDJ90369.1 - 7.5e-07 29.2 2.2 7.5e-07 29.2 2.2 4.1 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING fn3 PF00041.21 CDJ90369.1 - 1.2e-06 28.8 0.0 2.7e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain zf-RING_UBOX PF13445.6 CDJ90369.1 - 2.1e-05 24.5 2.7 2.1e-05 24.5 2.7 3.4 5 0 0 5 5 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDJ90369.1 - 7.7e-05 22.4 1.9 7.7e-05 22.4 1.9 4.1 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ90369.1 - 0.00019 21.3 1.2 0.00019 21.3 1.2 4.3 4 1 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ90369.1 - 0.00099 18.9 1.4 0.00099 18.9 1.4 4.2 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) CEBP_ZZ PF16366.5 CDJ90369.1 - 0.0014 18.9 2.6 0.0014 18.9 2.6 3.6 3 0 0 3 3 3 1 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-RING_5 PF14634.6 CDJ90369.1 - 0.0016 18.4 1.8 0.0016 18.4 1.8 4.0 4 0 0 4 4 2 1 zinc-RING finger domain DUF1106 PF06523.11 CDJ90369.1 - 0.051 13.6 0.2 4.3 7.5 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1106) Abhydrolase_8 PF06259.12 CDJ90369.1 - 0.067 12.8 0.4 0.42 10.2 0.2 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase DUF2397 PF09660.10 CDJ90369.1 - 0.095 11.6 1.3 0.13 11.1 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) DUF3584 PF12128.8 CDJ90369.1 - 0.22 9.0 9.6 0.3 8.6 9.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.15 CDJ90369.1 - 0.23 11.0 5.7 0.35 10.4 5.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Apolipoprotein PF01442.18 CDJ90369.1 - 0.25 11.2 4.8 0.45 10.4 4.8 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 CDJ90369.1 - 0.37 10.8 3.1 0.64 10.1 3.1 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF406 PF04175.12 CDJ90369.1 - 0.38 11.3 5.2 0.86 10.1 5.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF406) CortBP2 PF09727.9 CDJ90369.1 - 0.44 10.4 9.3 0.76 9.7 9.3 1.2 1 0 0 1 1 1 0 Cortactin-binding protein-2 ZapB PF06005.12 CDJ90369.1 - 0.51 10.8 6.4 8.2 6.9 0.6 2.5 2 0 0 2 2 2 0 Cell division protein ZapB Phage_Mu_Gam PF07352.12 CDJ90369.1 - 0.86 9.5 3.6 0.77 9.7 1.9 1.8 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein GAT PF03127.14 CDJ90369.1 - 1.8 8.9 6.1 0.25 11.7 0.9 2.2 2 0 0 2 2 2 0 GAT domain Uso1_p115_C PF04871.13 CDJ90369.1 - 2.2 8.7 5.7 4.3 7.7 5.7 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1664 PF07889.12 CDJ90369.1 - 2.8 8.0 6.9 2.2 8.4 3.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) IBR PF01485.21 CDJ90369.1 - 6.3 7.1 28.8 1.4 9.2 3.8 4.1 3 1 0 3 3 3 0 IBR domain, a half RING-finger domain Cep57_CLD_2 PF14197.6 CDJ90369.1 - 9.7 6.4 7.4 26 5.0 0.7 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 YkuD PF03734.14 CDJ90371.1 - 1.3e-07 32.2 0.2 8.4 6.8 0.0 5.2 4 1 1 5 5 5 3 L,D-transpeptidase catalytic domain DUF5399 PF17377.2 CDJ90371.1 - 8.9 6.1 13.4 17 5.2 0.0 4.9 5 0 0 5 5 5 0 Family of unknown function (DUF5399) PB1 PF00564.24 CDJ90372.1 - 0.0025 17.7 0.0 0.0035 17.2 0.0 1.2 1 0 0 1 1 1 1 PB1 domain SL4P PF17618.2 CDJ90372.1 - 0.0027 17.7 0.1 0.0037 17.3 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized Strongylid L4 protein DUF2457 PF10446.9 CDJ90372.1 - 0.53 9.4 5.2 0.66 9.0 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) 3-dmu-9_3-mt PF06983.13 CDJ90374.1 - 0.035 14.6 0.0 0.064 13.8 0.0 1.4 1 0 0 1 1 1 0 3-demethylubiquinone-9 3-methyltransferase gag-asp_proteas PF13975.6 CDJ90375.1 - 5.2e-08 33.4 0.7 1.3e-07 32.1 0.3 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 CDJ90375.1 - 2.8e-05 24.0 2.4 5.1e-05 23.2 2.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 CDJ90375.1 - 0.00075 19.2 1.3 0.002 17.8 1.3 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Asp_protease_2 PF13650.6 CDJ90375.1 - 0.0025 18.4 0.5 0.0066 17.1 0.5 1.8 1 1 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ90375.1 - 0.07 13.5 0.1 0.29 11.5 0.1 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease zf-CCHC_4 PF14392.6 CDJ90375.1 - 0.19 11.5 1.6 0.33 10.7 0.7 1.9 2 0 0 2 2 2 0 Zinc knuckle VESA1_N PF12785.7 CDJ90375.1 - 0.35 9.8 5.1 0.42 9.5 5.1 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 LRR_8 PF13855.6 CDJ90376.1 - 2e-56 187.6 48.1 3.2e-09 36.4 5.0 9.2 3 1 6 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 CDJ90376.1 - 6.3e-39 131.3 67.1 3.5e-07 30.4 2.1 11.4 3 3 9 14 14 14 14 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDJ90376.1 - 2.1e-11 43.7 32.4 0.00031 20.3 0.7 6.2 1 1 4 6 6 6 6 Leucine-rich repeat LRR_1 PF00560.33 CDJ90376.1 - 1.9e-09 36.7 56.1 4.4 8.2 0.0 17.7 19 1 0 19 19 19 4 Leucine Rich Repeat LRR_5 PF13306.6 CDJ90376.1 - 5.3e-07 29.7 3.2 1.2 9.1 0.0 4.8 3 2 1 4 4 4 3 BspA type Leucine rich repeat region (6 copies) DUF2322 PF10084.9 CDJ90376.1 - 0.034 14.2 1.5 1 9.4 0.0 3.3 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2322) YdiH PF15930.5 CDJ90376.1 - 0.087 13.0 0.4 2.9 8.1 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function LRR_6 PF13516.6 CDJ90376.1 - 2.3 8.5 59.6 2.7 8.3 0.4 13.2 13 0 0 13 13 13 0 Leucine Rich repeat DUF273 PF03314.14 CDJ90377.1 - 1.6e-90 302.4 3.8 2.2e-90 302.0 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Glyco_transf_34 PF05637.12 CDJ90377.1 - 2.8e-06 27.3 0.0 0.0037 17.0 0.0 2.2 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family PIF1 PF05970.14 CDJ90378.1 - 2.5e-70 237.5 0.1 3.1e-70 237.2 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CDJ90378.1 - 0.007 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Helitron_like_N PF14214.6 CDJ90379.1 - 2.9e-61 207.0 0.8 1e-60 205.2 0.0 2.2 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Ribosomal_L1 PF00687.21 CDJ90384.1 - 1.6e-10 41.0 0.0 2.6e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family WD40 PF00400.32 CDJ90385.1 - 0.017 16.0 5.6 0.46 11.5 0.0 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat WD40 PF00400.32 CDJ90386.1 - 9e-07 29.5 4.8 0.0056 17.5 0.4 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat LRR_6 PF13516.6 CDJ90387.1 - 7.1e-10 38.1 17.4 0.24 11.5 0.1 7.5 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.7 CDJ90387.1 - 2.1e-05 24.8 11.6 0.024 15.1 0.0 4.7 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ90387.1 - 0.053 13.3 14.9 1.9 8.3 2.0 4.5 3 3 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 CDJ90387.1 - 0.11 13.1 5.8 21 6.2 0.1 5.8 6 0 0 6 6 6 0 Leucine Rich Repeat Pkinase PF00069.25 CDJ90388.1 - 6e-64 216.0 0.0 8.7e-64 215.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CNH PF00780.22 CDJ90388.1 - 5.4e-52 177.1 0.1 8.1e-52 176.5 0.1 1.3 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.17 CDJ90388.1 - 3.5e-43 147.8 0.0 5e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ90388.1 - 0.00021 20.2 0.0 0.00033 19.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDJ90388.1 - 0.0099 15.2 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF2052 PF09747.9 CDJ90388.1 - 0.062 13.4 0.0 0.098 12.8 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) PCNA_N PF00705.18 CDJ90388.1 - 0.12 12.0 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain Peptidase_M20 PF01546.28 CDJ90389.1 - 1.2e-20 74.1 0.0 1.3e-19 70.7 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CDJ90389.1 - 7.8e-18 64.4 0.0 1.7e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CDJ90389.1 - 6.8e-06 25.9 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Folate_carrier PF01770.18 CDJ90390.1 - 5.2e-97 325.2 19.6 1.4e-96 323.8 19.6 1.6 1 1 0 1 1 1 1 Reduced folate carrier MFS_1 PF07690.16 CDJ90390.1 - 0.008 15.1 13.7 0.0097 14.9 13.7 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Adeno_E3_14_5 PF04834.12 CDJ90390.1 - 0.22 12.1 4.0 1.8 9.2 1.8 2.9 2 0 0 2 2 2 0 Early E3 14.5 kDa protein Lipase_3 PF01764.25 CDJ90391.1 - 2.1e-37 128.1 0.0 2.9e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 CDJ90391.1 - 0.022 14.3 0.5 0.08 12.5 0.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 CDJ90391.1 - 0.032 14.8 0.0 0.042 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDJ90391.1 - 0.033 13.5 0.0 0.064 12.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2048 PF09752.9 CDJ90391.1 - 0.034 13.3 0.3 0.084 12.0 0.2 1.6 1 1 1 2 2 2 0 Abhydrolase domain containing 18 Abhydrolase_8 PF06259.12 CDJ90391.1 - 0.049 13.3 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF676 PF05057.14 CDJ90391.1 - 0.11 12.0 0.1 0.41 10.1 0.1 1.8 1 1 0 1 1 1 0 Putative serine esterase (DUF676) PDZ PF00595.24 CDJ90392.1 - 4.1e-10 39.9 0.0 8.4e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PB1 PF00564.24 CDJ90392.1 - 7.8e-10 38.6 0.0 1.8e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 PB1 domain PDZ_6 PF17820.1 CDJ90392.1 - 2e-05 24.3 0.3 9.2e-05 22.2 0.0 2.2 3 0 0 3 3 3 1 PDZ domain RPN7 PF10602.9 CDJ90393.1 - 9e-45 152.5 0.3 9e-45 152.5 0.3 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 CDJ90393.1 - 8e-11 42.4 0.1 3.2e-10 40.5 0.0 2.1 2 0 0 2 2 2 1 PCI domain DUF2791 PF10923.8 CDJ90393.1 - 0.016 14.1 1.2 1.1 8.0 0.3 2.1 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) GAGBD PF16828.5 CDJ90393.1 - 0.072 13.2 0.5 0.2 11.8 0.5 1.7 1 0 0 1 1 1 0 GAG-binding domain on surface antigen COesterase PF00135.28 CDJ90393.1 - 0.11 11.3 0.2 0.17 10.7 0.2 1.2 1 0 0 1 1 1 0 Carboxylesterase family dsDNA_bind PF01984.20 CDJ90393.1 - 0.14 12.5 0.1 0.14 12.5 0.1 2.1 2 0 0 2 2 2 0 Double-stranded DNA-binding domain CLASP_N PF12348.8 CDJ90394.1 - 1.1e-26 93.9 18.2 1.8e-16 60.4 1.7 5.1 4 1 1 5 5 5 4 CLASP N terminal HEAT PF02985.22 CDJ90394.1 - 1.2e-09 37.6 5.5 4.5 7.8 0.0 8.6 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 CDJ90394.1 - 6.5e-08 32.9 3.6 0.082 13.3 0.0 7.3 6 3 1 8 8 8 2 HEAT repeats HEAT_EZ PF13513.6 CDJ90394.1 - 5.2e-05 23.7 2.4 2.7 8.6 0.0 5.7 4 1 0 4 4 4 1 HEAT-like repeat UME PF08064.13 CDJ90394.1 - 0.005 16.7 7.6 4.4 7.3 0.1 5.1 5 0 0 5 5 5 1 UME (NUC010) domain DUF1512 PF07431.12 CDJ90394.1 - 0.019 14.0 0.7 0.048 12.6 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) NOC3p PF07540.11 CDJ90394.1 - 0.14 12.6 0.1 1.7 9.2 0.1 2.6 2 0 0 2 2 2 0 Nucleolar complex-associated protein BAR_3 PF16746.5 CDJ90394.1 - 0.27 10.9 1.4 29 4.2 0.0 3.1 3 0 0 3 3 3 0 BAR domain of APPL family UNC45-central PF11701.8 CDJ90394.1 - 1.2 9.1 6.8 9.3 6.2 0.1 4.0 5 0 0 5 5 5 0 Myosin-binding striated muscle assembly central MOR2-PAG1_C PF14225.6 CDJ90394.1 - 1.6 8.6 8.5 0.17 11.8 2.3 2.4 3 0 0 3 3 3 0 Cell morphogenesis C-terminal MMS19_N PF14500.6 CDJ90394.1 - 2.2 7.8 7.7 14 5.2 0.1 4.7 4 2 1 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II NUC173 PF08161.12 CDJ90394.1 - 3.2 7.4 7.0 21 4.7 0.0 4.1 4 1 0 4 4 4 0 NUC173 domain MAGE_N PF12440.8 CDJ90395.1 - 9 7.1 8.4 2.5 8.9 1.1 2.4 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Pkinase PF00069.25 CDJ90396.1 - 8.4e-76 254.8 0.0 1.5e-75 254.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ90396.1 - 6.9e-48 163.2 0.0 1.2e-47 162.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 CDJ90396.1 - 2.1e-19 69.1 0.0 3.5e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 CDJ90396.1 - 1.5e-08 34.4 0.0 1e-07 31.6 0.0 2.2 2 1 0 3 3 3 1 Kinase-like Kdo PF06293.14 CDJ90396.1 - 0.00051 19.4 0.1 0.001 18.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDJ90396.1 - 0.00078 18.5 0.1 0.0015 17.5 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CDJ90396.1 - 0.1 12.2 0.3 0.2 11.2 0.3 1.4 1 0 0 1 1 1 0 RIO1 family Comm PF15957.5 CDJ90397.1 - 0.52 10.7 1.3 2.3 8.6 1.3 2.0 1 1 0 1 1 1 0 Commissureless Trypan_PARP PF05887.11 CDJ90398.1 - 0.00073 19.5 55.2 1.8e+04 -15.3 55.2 3.0 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SAP18 PF06487.12 CDJ90399.1 - 8.3e-39 133.0 0.0 1.1e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Fe_hyd_lg_C PF02906.14 CDJ90400.1 - 7.6e-33 114.2 0.0 2e-32 112.8 0.0 1.7 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Pup PF05639.11 CDJ90400.1 - 0.088 13.7 0.5 0.21 12.5 0.0 1.9 2 0 0 2 2 2 0 Pup-like protein Ca_bind_SSO6904 PF18249.1 CDJ90400.1 - 0.37 11.2 2.7 0.28 11.6 0.6 1.8 2 0 0 2 2 2 0 Calcium binding protein SSO6904 Sedlin_N PF04628.13 CDJ90401.1 - 1.1e-22 80.6 0.3 1.5e-22 80.1 0.3 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 CDJ90401.1 - 0.00035 20.5 0.1 0.00049 20.0 0.1 1.3 1 0 0 1 1 1 1 Sybindin-like family TAP42 PF04177.12 CDJ90402.1 - 1.3e-77 261.1 1.5 1.5e-77 260.8 1.5 1.1 1 0 0 1 1 1 1 TAP42-like family RNA_GG_bind PF10258.9 CDJ90403.1 - 2.3e-25 88.5 0.1 4.3e-25 87.6 0.1 1.5 1 0 0 1 1 1 1 PHAX RNA-binding domain Nipped-B_C PF12830.7 CDJ90403.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus ACBP PF00887.19 CDJ90404.1 - 2.4e-09 37.3 0.3 2.4e-09 37.3 0.3 2.4 2 0 0 2 2 2 1 Acyl CoA binding protein FERM_M PF00373.18 CDJ90404.1 - 0.32 11.4 1.9 8 6.9 0.0 2.8 2 1 1 3 3 3 0 FERM central domain UTRA PF07702.13 CDJ90405.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 UTRA domain Cas9-BH PF16593.5 CDJ90405.1 - 2.4 7.9 6.4 2.4 8.0 5.0 1.7 2 0 0 2 2 2 0 Bridge helix of CRISPR-associated endonuclease Cas9 FAM76 PF16046.5 CDJ90406.1 - 0.0038 16.6 5.7 0.0053 16.2 5.7 1.1 1 0 0 1 1 1 1 FAM76 protein zf-C2H2_2 PF12756.7 CDJ90406.1 - 0.072 13.4 1.6 0.1 12.9 0.4 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CDJ90406.1 - 0.074 13.4 3.0 0.44 10.9 3.0 2.2 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding OrsD PF12013.8 CDJ90406.1 - 0.58 10.6 3.1 0.36 11.3 0.2 2.0 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF1043 PF06295.12 CDJ90406.1 - 2.7 8.0 5.9 25 4.9 2.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) UBX PF00789.20 CDJ90407.1 - 2.7e-14 53.1 0.0 5.6e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain DUF966 PF06136.13 CDJ90407.1 - 0.066 12.9 7.7 0.11 12.2 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Endostatin PF06482.11 CDJ90407.1 - 1.6 8.2 6.1 2.3 7.6 6.1 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Hid1 PF12722.7 CDJ90407.1 - 3.2 5.8 7.4 4.3 5.4 7.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.9 CDJ90407.1 - 9.1 4.7 15.9 12 4.3 15.9 1.1 1 0 0 1 1 1 0 Macoilin family Pkinase PF00069.25 CDJ90408.1 - 4.3e-67 226.3 0.0 6.4e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ90408.1 - 5.8e-28 97.9 0.0 1e-27 97.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ90408.1 - 2.8e-06 26.4 0.0 6.6e-06 25.2 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CDJ90408.1 - 0.00012 21.5 0.0 0.00022 20.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDJ90408.1 - 0.0017 17.8 0.0 0.0068 15.8 0.0 2.1 2 1 0 2 2 2 1 Kinase-like NMD3 PF04981.13 CDJ90408.1 - 0.086 12.3 0.1 0.23 10.9 0.1 1.7 1 0 0 1 1 1 0 NMD3 family Peptidase_M16 PF00675.20 CDJ90409.1 - 1.3e-51 174.5 0.1 1.9e-51 174.0 0.1 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CDJ90409.1 - 5.4e-35 121.1 0.0 2.9e-32 112.2 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain DUF725 PF05267.12 CDJ90409.1 - 0.0057 16.6 0.2 0.013 15.5 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF725) DUF240 PF03086.14 CDJ90409.1 - 0.18 11.8 0.3 0.39 10.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF240) Copine PF07002.16 CDJ90410.1 - 2.7e-57 193.7 0.0 4.2e-57 193.1 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.30 CDJ90410.1 - 6.5e-06 26.4 0.0 0.00069 19.9 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 CDJ90410.1 - 0.1 12.7 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 vWA found in TerF C terminus Bestrophin PF01062.21 CDJ90411.1 - 1.2e-08 34.7 0.1 1.5e-08 34.4 0.1 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel tRNA-synt_His PF13393.6 CDJ90412.1 - 0.16 11.2 1.0 0.38 10.0 0.1 1.8 2 0 0 2 2 2 0 Histidyl-tRNA synthetase HD_2 PF12917.7 CDJ90412.1 - 0.54 10.0 4.2 5.7 6.6 0.7 2.8 2 1 1 3 3 3 0 HD containing hydrolase-like enzyme Sec7 PF01369.20 CDJ90413.1 - 4e-60 202.6 0.1 1.4e-59 200.9 0.0 1.9 2 0 0 2 2 2 1 Sec7 domain bVLRF1 PF18826.1 CDJ90413.1 - 2e-49 167.3 0.1 1.3e-48 164.6 0.0 2.4 3 0 0 3 3 3 1 bacteroidetes VLRF1 release factor PH PF00169.29 CDJ90413.1 - 2.3e-22 79.5 0.9 6.5e-22 78.0 0.1 2.2 2 0 0 2 2 2 1 PH domain VATC PF18716.1 CDJ90413.1 - 1.5e-08 34.4 2.5 3.9e-07 29.8 0.3 2.8 3 0 0 3 3 3 1 Vms1-associating treble clef domain Ank_2 PF12796.7 CDJ90413.1 - 9.5e-06 26.1 0.1 8.9e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) PH_11 PF15413.6 CDJ90413.1 - 0.00053 20.4 2.5 0.00075 19.9 0.0 2.5 3 0 0 3 3 3 1 Pleckstrin homology domain Ank_3 PF13606.6 CDJ90413.1 - 0.0022 18.3 0.0 0.009 16.5 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 CDJ90413.1 - 0.0043 17.3 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CDJ90413.1 - 0.0061 17.0 0.0 0.03 14.8 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 CDJ90413.1 - 0.019 15.6 0.0 0.077 13.6 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeats (many copies) acVLRF1 PF18859.1 CDJ90413.1 - 0.061 13.6 0.1 0.19 12.0 0.1 1.8 1 0 0 1 1 1 0 Actinobacteria/chloroflexi VLRF1 release factor NUDIX PF00293.28 CDJ90414.1 - 1.4e-13 51.0 0.0 2e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain SPC22 PF04573.12 CDJ90415.1 - 2.2e-51 173.7 0.8 2.5e-51 173.6 0.8 1.0 1 0 0 1 1 1 1 Signal peptidase subunit DUF3767 PF12597.8 CDJ90415.1 - 0.005 16.6 0.0 0.0082 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Ion_trans PF00520.31 CDJ90416.1 - 2.9e-47 161.0 33.7 3.6e-29 101.7 13.8 2.0 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 CDJ90416.1 - 0.99 8.0 32.2 0.5 9.0 4.8 4.5 4 1 0 4 4 4 0 Polycystin cation channel Ras PF00071.22 CDJ90417.1 - 1.4e-29 102.7 0.0 1.9e-29 102.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ90417.1 - 4.7e-17 62.3 0.0 6.8e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ90417.1 - 2.3e-06 27.2 0.0 2.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ90417.1 - 0.00046 19.6 0.0 0.0006 19.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CDJ90417.1 - 0.0043 16.6 0.0 0.011 15.3 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDJ90417.1 - 0.04 13.8 0.0 0.05 13.5 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase FeoB_N PF02421.18 CDJ90417.1 - 0.2 11.1 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B PhoLip_ATPase_C PF16212.5 CDJ90418.1 - 5.7e-72 242.5 22.2 5.7e-72 242.5 22.2 2.0 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CDJ90418.1 - 4.7e-26 90.3 0.3 1.2e-25 89.0 0.3 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CDJ90418.1 - 1.2e-11 44.5 0.0 2.5e-10 40.3 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CDJ90418.1 - 9e-10 39.2 9.1 2.8e-05 24.5 1.7 3.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CDJ90418.1 - 2.3e-05 24.0 0.2 8.4e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CDJ90418.1 - 0.006 16.4 1.4 0.014 15.2 1.4 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PMP1_2 PF08114.11 CDJ90418.1 - 0.34 10.7 5.6 0.055 13.2 0.5 2.3 2 0 0 2 2 2 0 ATPase proteolipid family SAM_1 PF00536.30 CDJ90419.1 - 5.6e-18 65.1 1.1 3.3e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CDJ90419.1 - 2.7e-13 49.8 0.6 1.1e-06 28.6 0.1 2.6 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) Tektin PF03148.14 CDJ90419.1 - 0.006 15.4 4.1 0.006 15.4 4.1 2.2 2 0 0 2 2 2 2 Tektin family DUF2312 PF10073.9 CDJ90419.1 - 0.031 13.9 0.2 0.085 12.5 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) LMBR1 PF04791.16 CDJ90419.1 - 0.74 8.6 4.1 1.1 8.1 4.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein RasGAP_C PF03836.15 CDJ90419.1 - 0.75 9.9 8.4 0.74 10.0 3.5 2.6 2 0 0 2 2 2 0 RasGAP C-terminus DUF4600 PF15372.6 CDJ90419.1 - 4.5 7.7 10.4 1.2 9.6 1.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) DUF4381 PF14316.6 CDJ90420.1 - 0.0071 16.6 0.2 0.012 15.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) DUF2207 PF09972.9 CDJ90420.1 - 0.0095 14.7 0.3 0.014 14.2 0.3 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) BatD PF13584.6 CDJ90420.1 - 0.13 11.1 0.1 0.18 10.6 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF4131 PF13567.6 CDJ90420.1 - 8.5 6.0 7.5 14 5.3 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Mucin15 PF15672.5 CDJ90421.1 - 0.39 10.2 16.0 0.49 9.8 16.0 1.2 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 DEAD PF00270.29 CDJ90422.1 - 1.3e-52 178.1 0.7 3.1e-51 173.6 0.0 2.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ90422.1 - 7.8e-23 80.9 0.0 2e-21 76.4 0.1 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 CDJ90422.1 - 3.1e-16 59.4 6.2 3.1e-16 59.4 6.2 3.4 3 0 0 3 3 3 1 DBP10CT (NUC160) domain zf-C2H2_jaz PF12171.8 CDJ90423.1 - 0.056 13.7 50.6 0.85 10.0 3.0 11.6 10 0 0 10 10 10 0 Zinc-finger double-stranded RNA-binding RNA_pol_Rpc4 PF05132.14 CDJ90423.1 - 7.3 7.0 11.5 0.73 10.3 0.1 3.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 Crystall PF00030.19 CDJ90424.1 - 0.0086 16.3 0.0 3.8 7.8 0.0 2.4 2 0 0 2 2 2 2 Beta/Gamma crystallin NAF PF03822.14 CDJ90424.1 - 0.27 11.5 2.3 0.67 10.2 0.0 2.5 3 0 0 3 3 3 0 NAF domain ECH_1 PF00378.20 CDJ90424.1 - 0.55 9.5 1.8 20 4.4 0.1 2.3 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase Ndc80_HEC PF03801.13 CDJ90424.1 - 3.9 7.1 5.7 18 4.9 0.5 2.7 1 1 2 3 3 3 0 HEC/Ndc80p family ACP_PD PF04336.12 CDJ90425.1 - 0.053 13.9 1.0 0.12 12.8 1.0 1.6 1 1 0 1 1 1 0 Acyl carrier protein phosphodiesterase CTP_transf_like PF01467.26 CDJ90426.1 - 5e-08 33.3 0.0 6.6e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 CDJ90426.1 - 0.0025 17.7 0.0 0.0033 17.3 0.0 1.2 1 0 0 1 1 1 1 FAD synthetase SH2 PF00017.24 CDJ90427.1 - 1.7e-08 34.5 0.0 4.9e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 SH2 domain LysR_substrate PF03466.20 CDJ90428.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 LysR substrate binding domain Neur_chan_LBD PF02931.23 CDJ90429.1 - 3.1e-38 131.4 0.0 3.4e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ90430.1 - 1.6e-38 133.1 0.0 2e-38 132.8 0.0 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Acyltransferase PF01553.21 CDJ90431.1 - 7.4e-16 58.0 0.0 1.5e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase DUF2675 PF11247.8 CDJ90431.1 - 0.057 13.6 0.0 0.19 11.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2675) HTH_Crp_2 PF13545.6 CDJ90431.1 - 0.08 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain GntR PF00392.21 CDJ90431.1 - 0.091 12.4 0.1 1.8 8.3 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Lipase_2 PF01674.18 CDJ90432.1 - 7.1e-72 241.5 0.1 8.3e-72 241.3 0.1 1.0 1 0 0 1 1 1 1 Lipase (class 2) Palm_thioest PF02089.15 CDJ90432.1 - 9.7e-05 22.3 0.1 0.00013 21.9 0.1 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 CDJ90432.1 - 0.032 13.7 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) UDPGT PF00201.18 CDJ90432.1 - 0.05 12.4 0.0 0.072 11.9 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Tctex-1 PF03645.13 CDJ90435.1 - 1.1e-14 54.5 0.0 1.5e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF3808 PF10300.9 CDJ90436.1 - 5.3e-125 417.9 2.7 6.6e-125 417.5 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 CDJ90436.1 - 0.00015 21.6 12.0 0.56 10.4 0.2 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ90436.1 - 0.001 19.5 4.0 2.5 8.7 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ90436.1 - 0.0014 18.4 1.0 2.3 8.2 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CDJ90436.1 - 0.069 12.5 1.8 1.5 8.1 0.0 2.9 3 0 0 3 3 3 0 MalT-like TPR region TPR_7 PF13176.6 CDJ90436.1 - 2.2 8.5 5.3 7.7 6.8 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat FAT PF02259.23 CDJ90437.1 - 8.1e-16 58.2 0.5 8.1e-16 58.2 0.5 2.0 2 0 0 2 2 2 1 FAT domain FATC PF02260.20 CDJ90437.1 - 0.0016 18.2 0.1 0.0053 16.5 0.1 1.9 1 0 0 1 1 1 1 FATC domain TetR_C_15 PF17918.1 CDJ90437.1 - 0.0058 17.4 3.2 2.5 8.9 0.1 4.8 3 0 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain PI3_PI4_kinase PF00454.27 CDJ90437.1 - 0.011 15.6 0.0 0.44 10.3 0.0 3.2 2 1 0 2 2 2 0 Phosphatidylinositol 3- and 4-kinase Dymeclin PF09742.9 CDJ90438.1 - 6.6e-146 487.3 10.6 7.4e-146 487.1 10.6 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 CDJ90438.1 - 1.1e-12 47.0 11.0 2.6e-07 29.2 4.1 3.3 3 0 0 3 3 3 3 High-temperature-induced dauer-formation protein Pho88 PF10032.9 CDJ90438.1 - 0.019 14.3 1.0 1.2 8.4 0.1 3.1 3 0 0 3 3 3 0 Phosphate transport (Pho88) adh_short PF00106.25 CDJ90439.1 - 3.7e-25 88.5 0.0 5.2e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ90439.1 - 1.6e-09 37.6 0.0 2.5e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ90439.1 - 3.5e-07 30.3 0.0 6e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CDJ90439.1 - 0.038 13.1 0.0 0.074 12.2 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MPC PF03650.13 CDJ90439.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial pyruvate carriers NAD_binding_10 PF13460.6 CDJ90439.1 - 0.2 11.6 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding zf-C3HC4_3 PF13920.6 CDJ90440.1 - 2.7e-05 23.9 11.8 2.7e-05 23.9 11.8 3.5 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ90440.1 - 0.00085 19.2 11.2 0.00085 19.2 11.2 3.6 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 CDJ90440.1 - 0.0036 17.6 12.5 0.0036 17.6 12.5 3.4 3 0 0 3 3 3 1 Ring finger domain DUF4187 PF13821.6 CDJ90440.1 - 0.3 10.9 5.0 0.22 11.3 1.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4187) Spec3 PF15795.5 CDJ90442.1 - 3.3e-24 85.2 8.6 4.2e-24 84.9 8.6 1.1 1 0 0 1 1 1 1 Ectodermal ciliogenesis protein DUF4728 PF15860.5 CDJ90443.1 - 0.0043 17.7 3.8 0.0043 17.7 3.8 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4728) DUF2085 PF09858.9 CDJ90443.1 - 0.32 11.5 5.1 2.5 8.6 5.1 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2085) MerC PF03203.14 CDJ90443.1 - 1.3 9.4 11.0 2.6 8.5 11.0 1.6 1 1 0 1 1 1 0 MerC mercury resistance protein Tetraspanin PF00335.20 CDJ90443.1 - 1.5 8.5 11.9 0.47 10.1 9.6 1.3 1 1 0 1 1 1 0 Tetraspanin family DHHC PF01529.20 CDJ90443.1 - 3.7 7.6 11.8 0.46 10.6 6.1 1.9 1 1 1 2 2 2 0 DHHC palmitoyltransferase DUF3093 PF11292.8 CDJ90443.1 - 5.2 7.3 6.2 0.37 11.0 0.6 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3093) DUF485 PF04341.12 CDJ90444.1 - 3.2 7.8 7.1 9.2 6.3 7.1 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF485 7TMR-DISM_7TM PF07695.11 CDJ90445.1 - 0.006 16.5 11.1 0.0069 16.3 11.1 1.0 1 0 0 1 1 1 1 7TM diverse intracellular signalling DUF1282 PF06930.12 CDJ90445.1 - 0.049 13.4 6.2 0.064 13.0 6.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) DUF2207 PF09972.9 CDJ90445.1 - 0.4 9.4 3.5 0.44 9.3 3.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF5090 PF17009.5 CDJ90445.1 - 4.1 7.3 7.9 4.4 7.2 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) Wzy_C PF04932.15 CDJ90445.1 - 5.3 6.6 8.7 11 5.6 7.9 2.0 1 1 0 1 1 1 0 O-Antigen ligase DDT PF02791.17 CDJ90446.1 - 7.7e-14 51.8 1.4 1.4e-13 50.9 1.4 1.4 1 0 0 1 1 1 1 DDT domain PHD PF00628.29 CDJ90446.1 - 5.5e-07 29.4 8.5 5.5e-07 29.4 8.5 2.3 2 0 0 2 2 2 1 PHD-finger WSD PF15613.6 CDJ90446.1 - 0.00028 21.3 1.5 0.0017 18.8 0.4 3.0 2 1 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD_2 PF13831.6 CDJ90446.1 - 0.0023 17.4 4.0 0.0073 15.8 4.0 1.9 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 CDJ90446.1 - 0.09 12.7 1.1 0.26 11.2 1.1 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 CDJ90446.1 - 1.4 8.9 7.5 3.5 7.6 7.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Zf_RING PF16744.5 CDJ90446.1 - 4 7.6 8.2 12 6.1 8.2 1.8 1 1 0 1 1 1 0 KIAA1045 RING finger Bromodomain PF00439.25 CDJ90447.1 - 4.9e-23 81.0 0.0 1.1e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 CDJ90447.1 - 2.2e-19 69.1 24.9 6e-10 38.9 7.7 2.5 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 CDJ90447.1 - 0.016 14.7 13.6 0.052 13.1 2.4 2.7 2 0 0 2 2 2 0 PHD-finger DUF4482 PF14818.6 CDJ90447.1 - 0.28 12.1 7.5 0.086 13.7 3.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4482) PHD_4 PF16866.5 CDJ90447.1 - 0.38 10.9 23.3 0.47 10.6 6.9 3.1 2 1 0 2 2 2 0 PHD-finger GST_C_2 PF13410.6 CDJ90448.1 - 1.1e-06 28.6 0.0 1.8e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 CDJ90448.1 - 0.013 15.2 0.0 0.023 14.5 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Thioredoxin_3 PF13192.6 CDJ90448.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain GST_C_3 PF14497.6 CDJ90448.1 - 0.18 12.0 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Astacin PF01400.24 CDJ90449.1 - 1.9e-25 89.6 0.0 2.4e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 CDJ90449.1 - 0.00023 21.0 0.4 0.00038 20.3 0.3 1.3 1 1 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.6 CDJ90449.1 - 0.00047 19.9 0.1 0.00061 19.5 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 CDJ90449.1 - 0.0018 18.8 0.1 0.0026 18.3 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CDJ90449.1 - 0.0029 17.8 0.1 0.0034 17.6 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Metallopep PF12044.8 CDJ90449.1 - 0.0042 15.7 0.1 0.0046 15.6 0.1 1.1 1 0 0 1 1 1 1 Putative peptidase family Peptidase_M66 PF10462.9 CDJ90449.1 - 0.0044 16.0 0.0 0.0045 16.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase M66 DUF4953 PF16313.5 CDJ90449.1 - 0.03 13.5 0.5 0.053 12.7 0.5 1.3 1 0 0 1 1 1 0 Met-zincin HTH_48 PF17906.1 CDJ90450.1 - 1.5e-15 57.1 0.2 3e-15 56.1 0.2 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_23 PF13384.6 CDJ90450.1 - 1.6e-06 27.8 0.1 0.011 15.5 0.0 2.4 2 0 0 2 2 2 2 Homeodomain-like domain HTH_Tnp_IS630 PF01710.16 CDJ90450.1 - 2.6e-06 27.5 0.0 3.1e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_38 PF13936.6 CDJ90450.1 - 2.9e-06 27.0 0.1 5.6e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 CDJ90450.1 - 6.1e-06 26.8 0.0 8.4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 CDJ90450.1 - 4e-05 23.6 0.0 0.47 10.6 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 CDJ90450.1 - 4.2e-05 23.7 0.4 8.9e-05 22.7 0.2 1.5 2 0 0 2 2 2 1 Transposase HTH_50 PF18024.1 CDJ90450.1 - 0.00027 20.5 0.5 0.00046 19.7 0.0 1.6 2 0 0 2 2 1 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 CDJ90450.1 - 0.0047 17.2 0.0 3 8.2 0.0 2.2 1 1 1 2 2 2 2 Transposase HTH_11 PF08279.12 CDJ90450.1 - 0.0063 16.4 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 HTH domain HTH_29 PF13551.6 CDJ90450.1 - 0.0066 16.4 0.1 0.28 11.2 0.0 2.3 1 1 1 2 2 2 1 Winged helix-turn helix Terminase_5 PF06056.12 CDJ90450.1 - 0.013 15.3 0.0 2.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) TnsD PF15978.5 CDJ90450.1 - 0.016 14.2 0.2 0.017 14.1 0.2 1.2 1 1 0 1 1 1 0 Tn7-like transposition protein D IF2_N PF04760.15 CDJ90450.1 - 0.027 14.3 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region HTH_Tnp_ISL3 PF13542.6 CDJ90450.1 - 0.039 13.4 0.1 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_36 PF13730.6 CDJ90450.1 - 0.04 13.9 0.0 0.26 11.3 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_6 PF01418.17 CDJ90450.1 - 0.065 13.2 0.0 0.18 11.8 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family HTH_10 PF04967.12 CDJ90450.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain HTH_5 PF01022.20 CDJ90450.1 - 0.13 12.1 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Phage_terminase PF10668.9 CDJ90450.1 - 0.14 12.2 0.1 0.68 10.0 0.0 2.1 2 1 1 3 3 3 0 Phage terminase small subunit NUMOD1 PF07453.13 CDJ90450.1 - 0.16 12.2 0.1 0.29 11.4 0.1 1.4 1 0 0 1 1 1 0 NUMOD1 domain Str_synth PF03088.16 CDJ90451.1 - 2.3e-17 62.9 0.0 3.2e-16 59.2 0.0 3.0 4 1 0 4 4 4 1 Strictosidine synthase SGL PF08450.12 CDJ90451.1 - 7.5e-06 25.7 0.0 0.00012 21.8 0.0 2.3 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Helicase_C PF00271.31 CDJ90452.1 - 2.9e-08 34.0 0.1 4.5e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain 7TM_GPCR_Srt PF10321.9 CDJ90453.1 - 9.5e-22 77.4 8.4 1.1e-21 77.1 8.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt 7TM_GPCR_Srt PF10321.9 CDJ90454.1 - 2e-30 105.9 4.4 2.4e-30 105.6 4.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt 7TM_GPCR_Srx PF10328.9 CDJ90454.1 - 0.00017 21.3 3.0 0.00022 20.9 3.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF5584 PF17822.1 CDJ90454.1 - 0.088 12.3 2.6 0.11 11.9 0.6 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5584) DUF3021 PF11457.8 CDJ90454.1 - 0.19 12.1 4.9 0.29 11.5 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) 7TM_GPCR_Srt PF10321.9 CDJ90455.1 - 3.1e-65 220.2 34.4 1.7e-53 181.6 22.1 2.0 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srt Spc42p PF11544.8 CDJ90455.1 - 0.43 10.6 1.0 48 4.0 0.1 2.8 2 0 0 2 2 2 0 Spindle pole body component Spc42p OppC_N PF12911.7 CDJ90455.1 - 8.4 6.5 9.8 0.52 10.3 0.1 3.1 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C WD40 PF00400.32 CDJ90456.1 - 3e-17 62.7 5.6 8.9e-06 26.4 0.0 5.6 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ90456.1 - 3.4e-11 43.3 0.0 0.62 10.4 0.0 5.2 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Arylsulfotran_2 PF14269.6 CDJ90456.1 - 0.0038 16.6 0.4 0.0057 16.1 0.4 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) eIF2A PF08662.11 CDJ90456.1 - 0.0053 16.7 0.1 0.069 13.0 0.0 2.6 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CDJ90456.1 - 0.018 13.7 0.1 2.5 6.7 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Kelch_5 PF13854.6 CDJ90457.1 - 6.5e-30 102.6 1.8 3.5e-05 23.7 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 CDJ90457.1 - 4.4e-28 97.0 3.1 1.8e-06 28.1 0.0 6.9 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 CDJ90457.1 - 9.1e-27 92.4 3.3 0.00042 20.5 0.0 6.7 4 1 2 6 6 6 6 Kelch motif Kelch_4 PF13418.6 CDJ90457.1 - 6.1e-23 80.6 5.8 0.00015 21.7 0.2 6.7 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 CDJ90457.1 - 8e-23 79.8 7.5 0.00015 21.3 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 CDJ90457.1 - 2.6e-17 62.0 7.0 0.021 14.8 0.0 7.2 6 1 0 6 6 6 6 Kelch motif fn3 PF00041.21 CDJ90457.1 - 1.8e-07 31.4 0.2 0.07 13.5 0.1 4.0 3 1 0 3 3 3 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CDJ90457.1 - 0.048 14.2 0.0 0.15 12.6 0.0 2.0 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Fz PF01392.22 CDJ90458.1 - 3.8e-29 101.6 3.9 3.8e-29 101.6 3.9 1.8 2 0 0 2 2 2 1 Fz domain Metallophos PF00149.28 CDJ90459.1 - 6.6e-34 118.2 0.0 8.5e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Exo70 PF03081.15 CDJ90459.1 - 0.11 11.5 0.1 0.19 10.7 0.1 1.3 1 0 0 1 1 1 0 Exo70 exocyst complex subunit Aldo_ket_red PF00248.21 CDJ90462.1 - 4.7e-46 157.3 0.5 2.1e-44 151.9 0.5 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family RE_SinI PF09570.10 CDJ90462.1 - 0.14 11.3 0.2 0.3 10.3 0.2 1.5 1 1 0 1 1 1 0 SinI restriction endonuclease Aldo_ket_red PF00248.21 CDJ90463.1 - 3.7e-43 147.8 0.1 1.6e-41 142.4 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 CDJ90464.1 - 2.6e-45 154.9 0.1 3.6e-43 147.9 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DCP2 PF05026.13 CDJ90465.1 - 1.5e-27 95.7 3.5 3e-27 94.8 3.5 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 CDJ90465.1 - 0.00075 19.5 0.1 0.16 12.0 0.0 2.6 1 1 1 2 2 2 2 NUDIX domain tRNA_m1G_MT PF01746.21 CDJ90466.1 - 5.5e-27 94.7 0.0 1.3e-26 93.5 0.0 1.7 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase RNA_Me_trans PF04252.13 CDJ90466.1 - 0.033 13.8 0.0 0.09 12.3 0.0 1.7 2 0 0 2 2 2 0 Predicted SAM-dependent RNA methyltransferase RNase_P_p30 PF01876.16 CDJ90467.1 - 4.7e-34 117.7 0.0 9.6e-31 106.9 0.0 2.3 1 1 1 2 2 2 2 RNase P subunit p30 RabGAP-TBC PF00566.18 CDJ90468.1 - 1.5e-41 142.4 0.3 1.8e-41 142.2 0.3 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PDZ_6 PF17820.1 CDJ90469.1 - 4e-23 81.0 4.6 6.3e-09 35.5 0.3 4.5 4 0 0 4 4 4 4 PDZ domain PDZ PF00595.24 CDJ90469.1 - 1.2e-22 80.0 4.4 5.9e-05 23.3 0.3 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 CDJ90469.1 - 1.6e-09 38.0 2.3 0.036 14.4 0.0 4.9 4 1 0 4 4 4 2 PDZ domain Guanylate_kin PF00625.21 CDJ90469.1 - 1.8e-08 34.3 0.1 8e-08 32.2 0.1 2.0 1 1 0 1 1 1 1 Guanylate kinase Tricorn_PDZ PF14685.6 CDJ90469.1 - 0.0034 17.3 1.3 3.4 7.7 0.0 3.6 3 0 0 3 3 3 2 Tricorn protease PDZ domain SH3_2 PF07653.17 CDJ90469.1 - 0.039 13.6 0.1 0.11 12.2 0.1 1.8 1 0 0 1 1 1 0 Variant SH3 domain Imm3 PF14425.6 CDJ90469.1 - 3.3 7.8 4.7 3.4 7.7 0.0 3.0 3 0 0 3 3 3 0 Immunity protein Imm3 AA_permease_2 PF13520.6 CDJ90470.1 - 8.6e-33 113.8 46.1 1.9e-18 66.5 21.7 2.0 1 1 1 2 2 2 2 Amino acid permease Membralin PF09746.9 CDJ90471.1 - 1.7e-134 448.6 3.8 2.4e-134 448.2 3.8 1.1 1 0 0 1 1 1 1 Tumour-associated protein Collagen PF01391.18 CDJ90472.1 - 5.8e-25 86.8 100.9 2.5e-09 36.8 34.0 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ90472.1 - 5e-07 29.7 0.2 6.9e-07 29.2 0.2 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ90473.1 - 1.6e-26 91.8 103.0 2e-10 40.3 37.7 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Integrase_H2C2 PF17921.1 CDJ90474.1 - 2e-15 56.7 0.7 5.6e-15 55.2 0.7 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 CDJ90474.1 - 3.3e-06 27.6 0.4 9.7e-06 26.1 0.4 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 CDJ90474.1 - 0.00024 21.0 2.4 0.00057 19.8 2.4 1.7 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 CDJ90474.1 - 0.078 13.6 0.3 0.22 12.2 0.3 1.9 1 0 0 1 1 1 0 Aspartyl protease OmdA PF13376.6 CDJ90474.1 - 0.12 12.4 0.1 0.37 10.8 0.1 1.8 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Methyltransf_11 PF08241.12 CDJ90475.1 - 3e-17 63.0 0.2 8e-17 61.7 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ90475.1 - 4.5e-15 56.1 0.9 1.2e-14 54.7 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain CMAS PF02353.20 CDJ90475.1 - 4.4e-13 49.2 0.0 5.8e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 CDJ90475.1 - 1.9e-12 47.3 0.1 2.8e-12 46.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ90475.1 - 8.8e-11 41.6 0.0 1.4e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 CDJ90475.1 - 6.2e-10 39.2 0.0 1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ90475.1 - 5.9e-09 36.6 0.0 1.1e-08 35.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CDJ90475.1 - 0.0016 18.4 0.0 0.005 16.7 0.0 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_4 PF02390.17 CDJ90475.1 - 0.013 15.0 0.3 0.037 13.5 0.2 1.9 2 0 0 2 2 2 0 Putative methyltransferase Sterol_MT_C PF08498.10 CDJ90475.1 - 0.026 14.8 0.0 0.065 13.6 0.0 1.6 1 0 0 1 1 1 0 Sterol methyltransferase C-terminal Methyltransf_2 PF00891.18 CDJ90475.1 - 0.03 13.6 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain PCMT PF01135.19 CDJ90475.1 - 0.032 14.0 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 CDJ90475.1 - 0.11 12.1 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase RT_RNaseH PF17917.1 CDJ90477.1 - 3.6e-30 104.3 0.0 8.5e-30 103.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ90477.1 - 2.5e-28 98.0 0.1 8.6e-28 96.3 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ90477.1 - 2.2e-14 53.3 0.2 4.4e-14 52.3 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDJ90477.1 - 1e-11 45.1 0.0 2e-10 40.9 0.0 2.7 3 0 0 3 3 3 1 Integrase core domain RVT_1 PF00078.27 CDJ90477.1 - 5.4e-11 42.4 0.1 9.2e-11 41.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CDJ90478.1 - 0.00056 20.4 0.0 0.0013 19.3 0.0 1.6 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease NHL PF01436.21 CDJ90479.1 - 2.1e-26 90.5 0.5 3.4e-06 26.8 0.1 5.4 5 0 0 5 5 5 3 NHL repeat SGL PF08450.12 CDJ90479.1 - 3.8e-06 26.7 0.1 0.0079 15.8 0.0 3.6 3 2 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Phytase-like PF13449.6 CDJ90479.1 - 0.0051 16.8 0.0 0.88 9.5 0.0 2.9 2 1 0 2 2 2 1 Esterase-like activity of phytase DUF5128 PF17170.4 CDJ90479.1 - 0.0056 15.9 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 6-bladed beta-propeller DUF3244 PF11589.8 CDJ90479.1 - 0.1 12.7 0.1 6.1 7.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3244) ClpS PF02617.17 CDJ90480.1 - 8.6e-22 76.7 0.2 9.8e-21 73.3 0.0 2.7 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS zf-UBR PF02207.20 CDJ90480.1 - 6.6e-19 67.8 17.1 1.7e-18 66.5 17.1 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) RVT_1 PF00078.27 CDJ90481.1 - 2.9e-51 174.1 0.6 1.4e-24 86.9 0.1 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3931 PF13082.6 CDJ90481.1 - 0.0089 16.2 0.5 6.9 6.9 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3931) Pox_D5 PF03288.16 CDJ90481.1 - 0.018 15.5 0.0 54 4.4 0.0 3.5 3 0 0 3 3 3 0 Poxvirus D5 protein-like CSN7a_helixI PF18392.1 CDJ90481.1 - 0.027 14.4 4.5 3.5 7.6 0.4 2.6 2 0 0 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain Rotavirus_VP1 PF12289.8 CDJ90481.1 - 0.31 10.0 2.8 5.3 6.0 0.0 2.4 2 1 1 3 3 3 0 Rotavirus VP1 C-terminal domain WD40 PF00400.32 CDJ90482.1 - 9.3e-14 51.6 2.3 0.0011 19.7 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ90482.1 - 1.3e-05 25.4 0.0 0.33 11.3 0.0 3.7 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Exo_endo_phos_2 PF14529.6 CDJ90484.1 - 0.0082 16.0 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase OATP PF03137.20 CDJ90485.1 - 0.14 10.4 0.1 0.16 10.2 0.1 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Presenilin PF01080.17 CDJ90486.1 - 0.0064 15.3 8.1 0.0081 15.0 8.1 1.1 1 0 0 1 1 1 1 Presenilin Neur_chan_memb PF02932.16 CDJ90486.1 - 0.018 15.1 3.1 0.022 14.9 3.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.6 CDJ90486.1 - 0.018 13.5 0.9 0.024 13.0 0.9 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MRP-S26 PF14943.6 CDJ90486.1 - 0.11 12.4 14.0 0.14 12.0 14.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Hid1 PF12722.7 CDJ90486.1 - 0.23 9.5 5.7 0.25 9.5 5.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2397 PF09660.10 CDJ90486.1 - 0.3 9.9 7.8 0.37 9.6 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) Zip PF02535.22 CDJ90486.1 - 0.33 10.1 0.4 0.38 9.9 0.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Activator_LAG-3 PF11498.8 CDJ90486.1 - 0.39 9.6 18.3 0.47 9.4 18.3 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 EOS1 PF12326.8 CDJ90486.1 - 0.46 10.4 2.0 0.63 9.9 2.0 1.3 1 0 0 1 1 1 0 N-glycosylation protein DDHD PF02862.17 CDJ90486.1 - 0.48 10.5 5.1 0.58 10.3 5.1 1.2 1 0 0 1 1 1 0 DDHD domain Ndc1_Nup PF09531.10 CDJ90486.1 - 1 8.0 4.8 1.1 7.9 4.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOBP PF15279.6 CDJ90486.1 - 1.3 9.6 11.4 1.6 9.3 11.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4834 PF16118.5 CDJ90486.1 - 2 9.4 18.0 1.1e+02 3.8 18.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ90486.1 - 2.4 7.7 17.6 3 7.4 17.6 1.1 1 0 0 1 1 1 0 Spt20 family DUF4407 PF14362.6 CDJ90486.1 - 3.2 7.0 8.3 3.9 6.8 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NPR3 PF03666.13 CDJ90486.1 - 4.9 5.8 16.4 6.2 5.5 16.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TERB2 PF15101.6 CDJ90486.1 - 8.4 6.4 11.1 12 5.9 11.1 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PDZ PF00595.24 CDJ90487.1 - 4.1e-59 196.9 2.1 2.5e-18 66.2 0.0 3.4 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.21 CDJ90487.1 - 2.5e-44 151.1 0.0 5.3e-44 150.1 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase L27_1 PF09058.10 CDJ90487.1 - 2.3e-21 75.5 4.0 2.3e-21 75.5 4.0 1.8 2 0 0 2 2 2 1 L27_1 PDZ_6 PF17820.1 CDJ90487.1 - 6.9e-19 67.4 1.3 3.5e-08 33.2 0.0 3.7 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 CDJ90487.1 - 1.6e-15 57.2 3.8 1.3e-05 25.5 0.2 3.5 3 0 0 3 3 3 3 PDZ domain SH3_1 PF00018.28 CDJ90487.1 - 1.3e-07 31.1 0.0 2.8e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDJ90487.1 - 7.4e-06 25.6 0.0 2e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Tricorn_PDZ PF14685.6 CDJ90487.1 - 0.0049 16.8 4.0 0.3 11.1 0.0 3.8 4 0 0 4 4 4 1 Tricorn protease PDZ domain SH3_9 PF14604.6 CDJ90487.1 - 0.0056 16.5 0.1 0.019 14.8 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain API5 PF05918.11 CDJ90488.1 - 5.5e-46 157.5 11.5 6.1e-46 157.3 11.5 1.0 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) Fucosidase_C PF16757.5 CDJ90488.1 - 0.013 16.0 0.1 0.09 13.4 0.0 2.2 2 0 0 2 2 2 0 Alpha-L-fucosidase C-terminal domain RasGEF_N_2 PF14663.6 CDJ90488.1 - 0.055 13.9 1.4 0.33 11.4 0.7 2.6 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT_2 PF13646.6 CDJ90488.1 - 0.065 13.6 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 HEAT repeats SecE PF00584.20 CDJ90489.1 - 0.0033 17.3 0.1 0.0057 16.6 0.1 1.3 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DUF148 PF02520.17 CDJ90490.1 - 3.5e-31 107.5 9.1 4.2e-31 107.3 9.1 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 DegS PF05384.11 CDJ90490.1 - 0.00017 21.1 4.8 0.00024 20.7 4.8 1.2 1 0 0 1 1 1 1 Sensor protein DegS Lin-8 PF03353.15 CDJ90490.1 - 0.0013 18.4 2.1 0.0015 18.1 2.1 1.0 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist Metal_resist PF13801.6 CDJ90490.1 - 0.0048 17.1 3.2 0.0048 17.1 3.2 3.0 2 1 1 3 3 3 1 Heavy-metal resistance GEMIN8 PF15348.6 CDJ90490.1 - 0.02 15.2 9.0 0.032 14.5 9.0 1.3 1 1 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 ApoA-II PF04711.13 CDJ90490.1 - 0.022 14.9 0.2 0.041 14.0 0.2 1.4 1 0 0 1 1 1 0 Apolipoprotein A-II (ApoA-II) Resolvase PF00239.21 CDJ90490.1 - 0.063 13.4 1.1 0.086 12.9 0.7 1.4 1 1 0 1 1 1 0 Resolvase, N terminal domain KLRAQ PF10205.9 CDJ90490.1 - 0.081 13.2 6.3 0.13 12.5 6.3 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein 4HB_MCP_1 PF12729.7 CDJ90490.1 - 0.18 11.4 5.9 0.24 10.9 4.8 1.8 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction Prominin PF05478.11 CDJ90490.1 - 0.19 9.7 2.6 0.23 9.4 2.6 1.1 1 0 0 1 1 1 0 Prominin Cauli_AT PF03233.13 CDJ90490.1 - 0.27 11.2 8.1 2.7 7.9 3.0 2.1 1 1 1 2 2 2 0 Aphid transmission protein PMC2NT PF08066.12 CDJ90490.1 - 0.31 11.8 2.2 0.4 11.4 0.9 1.7 1 1 1 2 2 2 0 PMC2NT (NUC016) domain GLE1 PF07817.13 CDJ90490.1 - 0.37 9.9 5.5 0.28 10.4 1.5 2.3 2 1 1 3 3 3 0 GLE1-like protein HSP70 PF00012.20 CDJ90490.1 - 0.38 8.9 6.2 0.48 8.6 6.2 1.0 1 0 0 1 1 1 0 Hsp70 protein CAMSAP_CC1 PF17095.5 CDJ90490.1 - 6.3 6.7 9.0 0.31 10.9 1.4 2.4 2 1 1 3 3 3 0 Spectrin-binding region of Ca2+-Calmodulin DUF148 PF02520.17 CDJ90491.1 - 1.5e-17 63.7 10.9 2.1e-17 63.2 10.9 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF148 ECM11 PF15463.6 CDJ90491.1 - 0.033 14.8 4.7 0.064 13.8 4.7 1.4 1 0 0 1 1 1 0 Extracellular mutant protein 11 Prominin PF05478.11 CDJ90491.1 - 0.049 11.6 4.6 0.064 11.2 4.6 1.1 1 0 0 1 1 1 0 Prominin FAA_hydrolase_N PF09298.11 CDJ90491.1 - 0.073 13.3 0.4 0.16 12.1 0.4 1.6 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal NFRKB_winged PF14465.6 CDJ90491.1 - 0.28 11.4 3.2 0.83 9.9 2.2 2.0 1 1 1 2 2 2 0 NFRKB Winged Helix-like DUF4298 PF14131.6 CDJ90491.1 - 0.42 10.6 6.9 0.68 9.9 3.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4298) ColG_sub PF18496.1 CDJ90491.1 - 0.68 10.1 6.4 0.3 11.2 2.7 2.0 1 1 1 2 2 2 0 Collagenase G catalytic helper subdomain Seryl_tRNA_N PF02403.22 CDJ90491.1 - 0.97 9.7 11.8 0.23 11.7 8.0 1.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF16 PF01519.16 CDJ90491.1 - 2.1 8.8 9.2 1.2 9.7 5.9 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 LRR_8 PF13855.6 CDJ90492.1 - 2.3e-63 209.8 36.3 3.1e-13 49.3 0.9 7.3 1 1 8 9 9 9 9 Leucine rich repeat LRR_5 PF13306.6 CDJ90492.1 - 2.3e-28 98.7 0.0 1.7e-09 37.7 0.0 3.5 2 1 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 CDJ90492.1 - 1.1e-24 86.0 31.6 1e-06 28.9 0.1 8.1 5 3 3 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDJ90492.1 - 7.8e-12 44.0 20.1 0.35 11.6 0.0 10.5 11 1 0 11 11 11 4 Leucine Rich Repeat LRR_9 PF14580.6 CDJ90492.1 - 6.1e-10 38.9 6.6 0.0047 16.5 2.0 3.6 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 CDJ90492.1 - 0.00047 20.0 31.0 0.24 11.5 0.2 8.6 9 0 0 9 9 9 3 Leucine Rich repeat LYRIC PF15686.5 CDJ90492.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family TMEM154 PF15102.6 CDJ90492.1 - 0.2 11.5 0.1 0.36 10.7 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family Taxilin PF09728.9 CDJ90493.1 - 3.4e-54 184.1 48.7 5.3e-54 183.5 48.7 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Rab5-bind PF09311.11 CDJ90493.1 - 0.0055 16.1 11.0 0.0055 16.1 11.0 3.0 1 1 1 3 3 3 1 Rabaptin-like protein DUF3008 PF11450.8 CDJ90493.1 - 0.051 13.7 1.7 3.2 8.0 0.3 3.1 2 1 0 2 2 2 0 Protein of unknwon function (DUF3008) DUF3788 PF12663.7 CDJ90493.1 - 0.18 11.8 8.4 0.27 11.2 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3788) DUF948 PF06103.11 CDJ90493.1 - 0.43 10.9 7.3 5 7.5 0.0 3.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.6 CDJ90493.1 - 1.5 8.1 28.0 0.023 14.0 6.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) YvbH_ext PF11724.8 CDJ90493.1 - 2 8.8 8.1 1.3 9.4 1.4 3.3 3 0 0 3 3 3 0 YvbH-like oligomerisation region ALIX_LYPXL_bnd PF13949.6 CDJ90493.1 - 2.7 7.2 33.8 1.8 7.8 12.8 2.4 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV Rootletin PF15035.6 CDJ90493.1 - 9.1 6.3 31.6 32 4.5 8.8 3.2 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion DUF4748 PF15932.5 CDJ90495.1 - 1.2e-06 28.1 0.1 3.7e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) Dynactin_p62 PF05502.13 CDJ90496.1 - 7e-20 71.3 25.6 1.1e-09 37.7 22.5 2.6 2 1 0 2 2 2 2 Dynactin p62 family DNA_RNApol_7kD PF03604.13 CDJ90496.1 - 0.23 11.2 0.2 0.23 11.2 0.2 4.1 4 1 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit SecG PF03840.14 CDJ90500.1 - 1.2 9.3 0.0 1.2 9.3 0.0 2.3 2 1 0 2 2 2 0 Preprotein translocase SecG subunit Peptidase_A17 PF05380.13 CDJ90501.1 - 1.5e-49 168.1 0.1 2.1e-49 167.7 0.1 1.1 1 0 0 1 1 1 1 Pao retrotransposon peptidase DWNN PF08783.11 CDJ90501.1 - 0.026 14.8 0.0 0.054 13.8 0.0 1.5 1 0 0 1 1 1 0 DWNN domain DUF1759 PF03564.15 CDJ90502.1 - 1.3e-21 77.1 1.8 5.1e-21 75.2 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 CDJ90502.1 - 2.1e-09 37.3 0.0 3.8e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 CDJ90502.1 - 0.0041 17.7 0.0 0.0088 16.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ90502.1 - 0.0045 17.5 0.0 0.01 16.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotran_gag_2 PF14223.6 CDJ90502.1 - 0.087 12.5 0.2 0.24 11.1 0.1 1.8 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DDE_3 PF13358.6 CDJ90503.1 - 5.9e-10 39.1 0.2 9.1e-10 38.5 0.2 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Transposase_1 PF01359.18 CDJ90503.1 - 1.5e-08 34.3 0.2 3e-08 33.3 0.2 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_26 PF13443.6 CDJ90503.1 - 0.0039 17.6 0.0 0.0088 16.5 0.0 1.5 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_10 PF04967.12 CDJ90503.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain RVT_1 PF00078.27 CDJ90506.1 - 9.2e-09 35.1 0.0 2.6e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sugar_tr PF00083.24 CDJ90507.1 - 1.3e-31 110.0 12.2 1.8e-31 109.5 12.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ90507.1 - 2.7e-15 56.1 5.0 1.3e-14 54.0 4.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CDJ90507.1 - 0.0019 17.6 0.3 0.0049 16.2 0.3 1.7 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB CNRIP1 PF15043.6 CDJ90509.1 - 1.6e-22 79.8 0.0 1.7e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 CB1 cannabinoid receptor-interacting protein 1 Ank_2 PF12796.7 CDJ90510.1 - 3.8e-82 270.9 12.5 2.9e-10 40.6 0.2 8.6 3 2 6 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ90510.1 - 4e-65 213.6 15.9 6e-05 23.3 0.0 17.1 17 0 0 17 17 17 12 Ankyrin repeat Ank_4 PF13637.6 CDJ90510.1 - 1.3e-62 207.3 22.9 6e-08 33.1 0.0 13.4 6 3 10 16 16 16 14 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ90510.1 - 6.4e-61 201.6 22.4 3.4e-09 36.8 0.1 13.2 10 3 4 14 14 14 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ90510.1 - 1.5e-53 172.4 20.5 0.0015 18.8 0.0 17.7 18 0 0 18 18 18 12 Ankyrin repeat TrkA_TMD PF18613.1 CDJ90511.1 - 1.4 8.4 6.6 1.9 8.0 6.6 1.1 1 0 0 1 1 1 0 Tyrosine kinase receptor A trans-membrane domain UFD1 PF03152.14 CDJ90512.1 - 1.2e-64 216.9 0.0 1.5e-64 216.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 UPRTase PF14681.6 CDJ90513.1 - 3.5e-70 235.7 0.0 5.4e-70 235.0 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 CDJ90513.1 - 1e-61 208.1 0.0 1.7e-61 207.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 CDJ90513.1 - 7.6e-09 36.2 0.0 2e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CDJ90513.1 - 8.4e-06 26.2 1.0 0.00029 21.2 0.3 3.0 2 1 0 2 2 2 1 AAA domain CPT PF07931.12 CDJ90513.1 - 6.9e-05 22.8 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 CDJ90513.1 - 0.0002 21.5 0.0 0.00079 19.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 CDJ90513.1 - 0.0051 16.6 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 2 Cytidylate kinase CoaE PF01121.20 CDJ90513.1 - 0.0061 16.2 0.0 0.068 12.8 0.0 2.1 2 0 0 2 2 2 1 Dephospho-CoA kinase Zeta_toxin PF06414.12 CDJ90513.1 - 0.0087 15.4 0.0 0.024 13.9 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin MobB PF03205.14 CDJ90513.1 - 0.042 13.8 0.1 0.095 12.6 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.23 CDJ90514.1 - 5.1e-21 74.9 0.0 8.7e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.22 CDJ90514.1 - 1.4e-17 63.7 2.8 1e-16 60.9 2.8 2.3 1 1 0 1 1 1 1 GTP1/OBG FeoB_N PF02421.18 CDJ90514.1 - 0.001 18.6 0.0 0.0023 17.5 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CDJ90514.1 - 0.027 14.5 0.0 5.2 7.1 0.0 2.2 1 1 1 2 2 2 0 Dynamin family ABC_tran PF00005.27 CDJ90514.1 - 0.039 14.5 0.1 0.12 12.9 0.0 1.8 2 0 0 2 2 2 0 ABC transporter cobW PF02492.19 CDJ90514.1 - 0.054 13.1 0.0 6.2 6.4 0.0 2.5 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 CDJ90514.1 - 0.18 11.2 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Pkinase PF00069.25 CDJ90515.1 - 0.00013 21.4 0.0 0.014 14.8 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ90515.1 - 0.032 13.5 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase A1_Propeptide PF07966.12 CDJ90515.1 - 0.04 13.8 2.2 1.5 8.7 0.0 2.7 3 0 0 3 3 3 0 A1 Propeptide Kdo PF06293.14 CDJ90515.1 - 0.077 12.3 0.0 0.14 11.5 0.0 1.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MOSC PF03473.17 CDJ90516.1 - 4.5e-28 97.9 0.0 1.1e-27 96.6 0.0 1.7 2 0 0 2 2 2 1 MOSC domain MOSC_N PF03476.16 CDJ90516.1 - 6.2e-24 84.2 0.0 9.5e-24 83.6 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain HPS3_N PF14761.6 CDJ90516.1 - 0.062 12.8 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 Baculo_p24 PF05073.12 CDJ90517.1 - 0.02 14.7 0.2 0.031 14.1 0.2 1.3 1 0 0 1 1 1 0 Baculovirus P24 capsid protein HAUS6_N PF14661.6 CDJ90517.1 - 0.062 12.9 0.3 0.071 12.7 0.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus ABC_tran_CTD PF16326.5 CDJ90517.1 - 0.088 13.1 0.1 0.35 11.2 0.1 1.9 1 1 1 2 2 2 0 ABC transporter C-terminal domain Exonuc_VII_L PF02601.15 CDJ90517.1 - 0.097 12.2 0.7 0.11 12.0 0.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2508 PF10704.9 CDJ90517.1 - 0.16 12.1 2.6 0.26 11.5 2.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2508) SapB_1 PF05184.15 CDJ90518.1 - 0.0013 18.7 0.9 0.0013 18.7 0.9 1.8 3 0 0 3 3 3 1 Saposin-like type B, region 1 SapB_2 PF03489.17 CDJ90518.1 - 0.0099 16.0 0.1 0.0099 16.0 0.1 2.2 3 0 0 3 3 3 1 Saposin-like type B, region 2 IU_nuc_hydro PF01156.19 CDJ90520.1 - 1.4e-64 218.6 0.1 1.8e-64 218.3 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase ZapB PF06005.12 CDJ90523.1 - 0.004 17.6 1.8 0.004 17.6 1.8 5.9 4 2 1 5 5 5 1 Cell division protein ZapB TPR_MLP1_2 PF07926.12 CDJ90523.1 - 0.026 14.6 4.7 0.026 14.6 4.7 5.6 2 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein Pox_A_type_inc PF04508.12 CDJ90523.1 - 0.037 13.9 7.2 2.9 7.9 0.5 4.6 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat ATP-synt_Eps PF04627.13 CDJ90523.1 - 0.071 13.1 0.0 2.6 8.1 0.0 3.0 2 0 0 2 2 2 0 Mitochondrial ATP synthase epsilon chain bZIP_1 PF00170.21 CDJ90523.1 - 1.5 9.0 43.2 3.2 7.9 3.2 6.6 5 1 2 7 7 7 0 bZIP transcription factor Lectin_N PF03954.14 CDJ90523.1 - 1.9 8.2 32.0 0.59 9.9 6.5 5.2 3 3 2 5 5 5 0 Hepatic lectin, N-terminal domain DUF4407 PF14362.6 CDJ90523.1 - 4 6.7 42.7 1.3 8.3 17.4 3.4 1 1 1 3 3 3 0 Domain of unknown function (DUF4407) DUF2935 PF11155.8 CDJ90523.1 - 5.4 7.4 16.8 45 4.4 0.1 4.3 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) ATG16 PF08614.11 CDJ90523.1 - 6.5 6.9 61.6 0.22 11.8 2.2 4.2 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 CDJ90523.1 - 9.5 5.6 54.2 0.13 11.7 20.4 3.3 2 1 1 3 3 3 0 Golgin subfamily A member 5 Pro_isomerase PF00160.21 CDJ90524.1 - 3e-49 167.3 0.1 3.4e-49 167.1 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TRM13 PF05206.14 CDJ90525.1 - 5e-56 190.1 0.1 1.4e-55 188.7 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 CDJ90525.1 - 2e-07 30.6 0.3 2e-07 30.6 0.3 2.9 3 0 0 3 3 3 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.12 CDJ90525.1 - 0.00031 20.6 4.2 0.00031 20.6 4.2 2.1 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.6 CDJ90525.1 - 0.00076 19.5 3.1 0.009 16.0 3.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain CDP-OH_P_transf PF01066.21 CDJ90526.1 - 2.5e-16 60.2 0.1 2.5e-16 60.2 0.1 3.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ESF1 PF18209.1 CDJ90526.1 - 0.42 10.6 3.6 1 9.3 3.6 1.6 1 0 0 1 1 1 0 Embryo surrounding factor 1 7TM_GPCR_Srv PF10323.9 CDJ90529.1 - 4e-16 59.2 16.7 5.1e-16 58.9 16.7 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 CDJ90529.1 - 1.3e-13 51.2 18.2 1.9e-13 50.7 17.9 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Srg PF02118.21 CDJ90529.1 - 2.1e-11 44.0 16.2 3.5e-11 43.3 16.2 1.3 1 1 0 1 1 1 1 Srg family chemoreceptor 7tm_1 PF00001.21 CDJ90529.1 - 0.2 10.9 12.7 0.43 9.8 12.0 1.9 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) CAP PF00188.26 CDJ90530.1 - 1.6e-20 74.2 7.2 2.5e-20 73.6 7.2 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TT_ORF2 PF02957.15 CDJ90530.1 - 0.073 14.0 3.4 0.13 13.1 3.4 1.5 1 0 0 1 1 1 0 TT viral ORF2 Sulfate_transp PF00916.20 CDJ90531.1 - 2.3e-32 112.2 22.9 3.3e-32 111.7 22.9 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CDJ90531.1 - 1.5e-18 66.5 0.0 3.2e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 CDJ90531.1 - 9.5e-05 22.7 0.0 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 STAS domain IFT81_CH PF18383.1 CDJ90532.1 - 1.2e-42 145.1 0.1 1.2e-42 145.1 0.1 3.0 3 1 1 4 4 4 1 Intraflagellar transport 81 calponin homology domain Spc7 PF08317.11 CDJ90532.1 - 0.00027 19.9 63.7 0.0072 15.2 17.4 4.2 2 1 3 5 5 5 4 Spc7 kinetochore protein MbeD_MobD PF04899.12 CDJ90532.1 - 0.0079 16.3 8.3 0.0079 16.3 8.3 5.2 5 2 0 6 6 6 1 MbeD/MobD like DUF1843 PF08898.10 CDJ90532.1 - 0.66 10.5 6.5 14 6.3 0.1 5.2 4 1 1 5 5 5 0 Domain of unknown function (DUF1843) LAGLIDADG_WhiA PF14527.6 CDJ90532.1 - 1.1 9.4 5.4 1.2 9.2 1.0 3.1 2 1 0 2 2 2 0 WhiA LAGLIDADG-like domain DUF5564 PF17719.1 CDJ90532.1 - 1.2 9.3 7.1 3.3 7.9 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5564) Sulfotransfer_2 PF03567.14 CDJ90532.1 - 1.9 8.3 6.1 0.33 10.8 1.7 2.0 2 0 0 2 2 2 0 Sulfotransferase family DUF812 PF05667.11 CDJ90532.1 - 8.1 5.2 62.1 0.11 11.4 15.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF812) GIT_CC PF16559.5 CDJ90533.1 - 0.073 12.9 0.2 0.073 12.9 0.2 2.4 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Baculo_p24 PF05073.12 CDJ90533.1 - 4.6 7.0 10.4 4.7 7.0 6.4 2.6 2 1 0 2 2 2 0 Baculovirus P24 capsid protein Ras PF00071.22 CDJ90534.1 - 2.3e-53 180.1 0.0 2.8e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ90534.1 - 5.7e-37 126.6 0.0 8.7e-37 126.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ90534.1 - 1.6e-14 53.8 0.0 1.9e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ90534.1 - 9.8e-07 28.4 0.0 1.7e-06 27.6 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDJ90534.1 - 2.5e-06 27.5 0.0 4.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ90534.1 - 4.4e-05 23.1 0.1 0.00017 21.2 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CDJ90534.1 - 7.5e-05 22.2 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 CDJ90534.1 - 0.00075 19.3 0.9 0.099 12.4 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 CDJ90534.1 - 0.0029 18.0 0.0 0.0052 17.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CDJ90534.1 - 0.0077 16.7 0.0 0.027 14.9 0.0 2.0 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 CDJ90534.1 - 0.0081 16.1 0.0 0.43 10.5 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase NACHT PF05729.12 CDJ90534.1 - 0.012 15.6 0.1 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.9 CDJ90534.1 - 0.015 15.1 0.1 0.069 12.9 0.1 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 CDJ90534.1 - 0.02 14.9 0.1 0.089 12.8 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CDJ90534.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 CDJ90534.1 - 0.034 14.4 0.4 0.15 12.3 0.2 2.2 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CDJ90534.1 - 0.047 13.7 0.0 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FeoB_N PF02421.18 CDJ90534.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B Ras PF00071.22 CDJ90535.1 - 2.7e-32 111.6 0.0 3.5e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ90535.1 - 3.3e-26 91.9 0.0 4.5e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ90535.1 - 6.6e-12 45.2 0.1 8.8e-12 44.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ90535.1 - 0.0014 18.0 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CDJ90535.1 - 0.0081 15.6 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Acyl-CoA_dh_1 PF00441.24 CDJ90536.1 - 4.3e-26 91.9 1.1 6e-26 91.4 0.2 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 CDJ90536.1 - 1.8e-22 79.9 0.0 3.2e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 CDJ90536.1 - 8.4e-14 51.6 0.0 1.6e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CDJ90536.1 - 2.7e-06 27.7 0.1 7.5e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Synaptobrevin PF00957.21 CDJ90538.1 - 7.2e-23 80.2 0.5 8.8e-23 79.9 0.5 1.0 1 0 0 1 1 1 1 Synaptobrevin PMP1_2 PF08114.11 CDJ90538.1 - 0.0037 17.0 0.7 0.018 14.8 1.3 1.7 2 0 0 2 2 2 1 ATPase proteolipid family COG2 PF06148.11 CDJ90538.1 - 0.0081 16.2 0.7 0.01 15.9 0.7 1.1 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 CDH1_2_SANT_HL1 PF18375.1 CDJ90538.1 - 0.011 16.4 0.3 0.014 16.0 0.3 1.3 1 0 0 1 1 1 0 CDH1/2 SANT-Helical linker 1 PDE4_UCR PF18100.1 CDJ90538.1 - 0.015 16.0 0.3 0.019 15.6 0.3 1.1 1 0 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) kleA_kleC PF17383.2 CDJ90538.1 - 0.024 15.0 3.4 0.029 14.7 3.4 1.1 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A Spc7 PF08317.11 CDJ90538.1 - 0.033 13.1 0.4 0.038 12.9 0.4 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein MCU PF04678.13 CDJ90538.1 - 0.11 12.6 0.7 0.14 12.3 0.7 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Fzo_mitofusin PF04799.13 CDJ90538.1 - 0.16 11.5 1.4 0.17 11.4 0.7 1.3 1 1 0 1 1 1 0 fzo-like conserved region DUF1664 PF07889.12 CDJ90538.1 - 1.9 8.5 5.2 0.63 10.1 1.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) NOT2_3_5 PF04153.18 CDJ90539.1 - 8.5e-32 110.0 0.5 1.5e-31 109.2 0.5 1.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family zf-C2H2 PF00096.26 CDJ90541.1 - 9.9e-19 66.7 25.1 5.9e-05 23.3 0.2 6.2 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ90541.1 - 9.7e-14 51.1 15.0 1.3e-07 31.8 0.4 4.7 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDJ90541.1 - 1.1e-09 38.3 21.4 0.0051 17.5 0.2 6.2 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDJ90541.1 - 3.1e-05 23.8 4.3 0.024 14.6 0.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 CDJ90541.1 - 6.9e-05 23.4 18.6 0.86 10.3 1.4 5.5 1 1 4 5 5 5 3 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 CDJ90541.1 - 0.008 16.4 7.8 15 6.0 0.5 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 CDJ90541.1 - 0.0094 16.1 10.7 0.31 11.2 0.7 4.2 1 1 2 4 4 4 1 Aberrant zinc-finger zf-H2C2_5 PF13909.6 CDJ90541.1 - 0.017 14.9 8.7 2.4 8.0 0.0 3.9 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 CDJ90541.1 - 0.031 14.0 0.1 0.19 11.5 0.2 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 CDJ90541.1 - 0.075 13.5 2.1 32 5.1 0.3 3.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type PcF PF09461.10 CDJ90541.1 - 1.6 9.1 4.1 31 5.0 1.1 2.9 2 0 0 2 2 2 0 Phytotoxin PcF protein DUF629 PF04780.12 CDJ90541.1 - 4.2 5.8 8.3 0.094 11.2 1.3 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF629) VWA PF00092.28 CDJ90542.1 - 1.8e-14 54.4 0.0 2.2e-12 47.6 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain Lectin_C PF00059.21 CDJ90542.1 - 1.7e-10 41.6 0.4 4e-10 40.4 0.4 1.7 1 0 0 1 1 1 1 Lectin C-type domain VWA_2 PF13519.6 CDJ90542.1 - 0.00037 21.1 0.0 0.00097 19.8 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Gemini_coat PF00844.18 CDJ90543.1 - 0.56 9.6 6.3 0.067 12.6 1.8 1.6 1 1 1 2 2 2 0 Geminivirus coat protein/nuclear export factor BR1 family RhoGEF PF00621.20 CDJ90544.1 - 5.2e-17 62.7 0.3 1e-16 61.7 0.0 1.6 2 0 0 2 2 2 1 RhoGEF domain 4HB_MCP_1 PF12729.7 CDJ90545.1 - 0.011 15.2 0.1 0.12 11.9 0.1 2.0 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction DUF4358 PF14270.6 CDJ90545.1 - 0.16 12.2 0.2 0.73 10.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) PSK_trans_fac PF07704.11 CDJ90545.1 - 0.25 12.1 1.9 0.28 11.9 0.2 2.0 2 1 0 2 2 2 0 Rv0623-like transcription factor Peptidase_A17 PF05380.13 CDJ90549.1 - 7.5e-35 120.3 0.1 7.5e-35 120.3 0.1 1.4 2 0 0 2 2 2 1 Pao retrotransposon peptidase PX PF00787.24 CDJ90550.1 - 3.8e-26 91.3 0.1 5e-26 90.9 0.1 1.2 1 0 0 1 1 1 1 PX domain RdRP_1 PF00680.20 CDJ90550.1 - 0.075 11.5 0.0 0.099 11.1 0.0 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase SNF2_N PF00176.23 CDJ90551.1 - 1.2e-55 188.6 0.1 2e-55 187.9 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ90551.1 - 8.6e-17 61.5 0.0 2.5e-16 60.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 CDJ90551.1 - 1.1e-07 31.3 0.2 3.5e-07 29.7 0.2 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 CDJ90551.1 - 2.7e-06 27.5 0.0 1.3e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ90551.1 - 2.8e-05 23.9 0.0 7.6e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Tex_N PF09371.10 CDJ90552.1 - 1.6e-12 47.5 5.4 1.7e-12 47.4 5.4 1.0 1 0 0 1 1 1 1 Tex-like protein N-terminal domain Ubiquitin_5 PF18037.1 CDJ90552.1 - 0.0018 18.6 0.6 0.0025 18.1 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain Peptidase_A17 PF05380.13 CDJ90553.1 - 1.4e-28 99.9 0.0 2.4e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Pao retrotransposon peptidase DUF5641 PF18701.1 CDJ90553.1 - 1.6e-19 69.8 4.6 1.1e-14 54.3 0.1 2.4 2 0 0 2 2 2 2 Family of unknown function (DUF5641) rve PF00665.26 CDJ90553.1 - 6.4e-11 42.5 0.0 1.3e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ90553.1 - 2.7e-09 37.0 1.2 6.5e-09 35.8 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CDJ90553.1 - 0.0011 19.1 1.5 0.0011 19.1 1.5 2.5 2 1 0 2 2 2 1 H2C2 zinc finger rve_3 PF13683.6 CDJ90553.1 - 0.015 15.0 0.0 0.043 13.6 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain RVT_3 PF13456.6 CDJ90553.1 - 0.13 12.1 0.1 0.37 10.6 0.1 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like DUF1759 PF03564.15 CDJ90554.1 - 7.4e-10 38.9 0.2 2.6e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 CDJ90554.1 - 3.9e-09 36.5 0.1 1.5e-08 34.6 0.1 2.0 1 1 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 CDJ90554.1 - 7.4e-05 23.3 0.2 0.00033 21.3 0.1 2.0 1 1 1 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 CDJ90554.1 - 0.00019 21.2 0.1 0.00035 20.3 0.1 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CDJ90554.1 - 0.00046 20.7 0.1 0.0014 19.1 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.8 CDJ90554.1 - 0.0038 16.8 0.2 0.0083 15.7 0.2 1.6 1 0 0 1 1 1 1 Ty3 transposon peptidase Y_phosphatase PF00102.27 CDJ90555.1 - 1.6e-74 250.5 0.2 2e-74 250.1 0.2 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CDJ90555.1 - 0.0017 18.3 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CDJ90555.1 - 0.0078 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CDJ90555.1 - 0.01 16.0 0.1 0.049 13.8 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 CDJ90555.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family RAB3GAP2_N PF14655.6 CDJ90556.1 - 1.8e-19 70.3 0.1 2.5e-19 69.8 0.1 1.2 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus RAB3GAP2_C PF14656.6 CDJ90556.1 - 1.1e-07 30.5 0.7 4.3e-07 28.6 0.7 1.8 1 1 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit C-terminus UDPG_MGDP_dh_N PF03721.14 CDJ90557.1 - 1.9e-63 213.4 0.0 3e-63 212.8 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 CDJ90557.1 - 1.1e-37 128.7 0.4 6.6e-35 119.7 0.2 3.0 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 CDJ90557.1 - 2.2e-31 107.9 0.0 4.3e-31 107.0 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain 3HCDH_N PF02737.18 CDJ90557.1 - 0.0049 16.8 0.0 0.52 10.2 0.0 2.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 CDJ90557.1 - 0.02 15.1 0.0 1.4 9.0 0.0 3.2 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase OLF PF02191.16 CDJ90558.1 - 6.4e-59 199.5 1.4 8e-59 199.2 1.4 1.1 1 0 0 1 1 1 1 Olfactomedin-like domain Collagen PF01391.18 CDJ90558.1 - 1.8e-07 30.8 15.2 3.4e-07 29.9 15.2 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF3143 PF11341.8 CDJ90558.1 - 0.15 12.4 0.1 2.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3143) Tropomodulin PF03250.14 CDJ90559.1 - 3.5e-50 169.7 2.0 3.5e-50 169.7 2.0 2.2 2 0 0 2 2 2 1 Tropomodulin Mucin PF01456.17 CDJ90560.1 - 0.0012 18.8 4.6 0.002 18.1 4.6 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein CD225 PF04505.12 CDJ90560.1 - 0.029 14.5 2.4 0.046 13.8 1.2 2.0 1 1 1 2 2 2 0 Interferon-induced transmembrane protein SpoIIIAH PF12685.7 CDJ90560.1 - 0.032 14.1 2.3 0.047 13.5 2.3 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF2946 PF11162.8 CDJ90560.1 - 0.062 14.0 1.2 0.12 13.0 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) CLN3 PF02487.17 CDJ90560.1 - 0.1 11.6 0.7 0.15 11.1 0.7 1.2 1 0 0 1 1 1 0 CLN3 protein FAM176 PF14851.6 CDJ90560.1 - 0.1 12.2 0.2 0.17 11.6 0.2 1.2 1 0 0 1 1 1 0 FAM176 family DUF4381 PF14316.6 CDJ90560.1 - 0.11 12.8 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PDZ_5 PF17817.1 CDJ90562.1 - 9.2e-22 77.1 0.1 2.7e-21 75.6 0.1 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CDJ90562.1 - 5.4e-12 45.9 0.2 1.5e-11 44.5 0.2 1.8 1 0 0 1 1 1 1 PDZ domain SAM_2 PF07647.17 CDJ90562.1 - 1.8e-10 40.7 0.1 3.8e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CDJ90562.1 - 6.3e-08 32.9 0.2 1.4e-07 31.9 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CREPT PF16566.5 CDJ90562.1 - 0.015 15.4 15.8 0.026 14.7 14.7 1.8 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour PDZ_6 PF17820.1 CDJ90562.1 - 0.017 15.0 2.3 0.096 12.5 0.3 3.0 2 1 1 3 3 3 0 PDZ domain ATG16 PF08614.11 CDJ90562.1 - 0.085 13.1 27.2 0.18 12.0 22.2 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 CDJ90562.1 - 0.12 12.7 13.2 0.13 12.5 11.4 2.1 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3584 PF12128.8 CDJ90562.1 - 0.13 9.8 18.6 0.19 9.2 18.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BshC PF10079.9 CDJ90562.1 - 0.47 9.1 10.8 0.78 8.4 10.8 1.4 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC DUF4407 PF14362.6 CDJ90562.1 - 0.57 9.5 9.6 1.3 8.3 9.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Uds1 PF15456.6 CDJ90562.1 - 0.62 10.2 23.8 1.4 9.1 12.2 3.5 2 1 1 3 3 3 0 Up-regulated During Septation VSG_B PF13206.6 CDJ90562.1 - 2.2 7.5 7.2 4.1 6.5 7.2 1.5 1 0 0 1 1 1 0 Trypanosomal VSG domain T3SSipB PF16535.5 CDJ90562.1 - 3.8 8.0 11.7 0.95 9.9 4.3 2.2 1 1 1 2 2 2 0 Type III cell invasion protein SipB DUF2802 PF10975.8 CDJ90562.1 - 4.8 7.4 12.3 3.4 7.8 2.7 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2802) DUF3450 PF11932.8 CDJ90562.1 - 5.8 6.1 16.1 11 5.3 14.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 CDJ90562.1 - 6.4 6.8 15.0 0.85 9.7 6.6 2.9 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 CDJ90562.1 - 6.9 5.4 27.1 0.27 10.1 21.1 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 CDJ90562.1 - 7.5 4.3 9.2 16 3.2 9.2 1.6 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2621 PF11084.8 CDJ90563.1 - 0.017 15.1 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) DUF563 PF04577.14 CDJ90564.1 - 3.2e-07 30.7 0.0 5.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Tropomyosin_1 PF12718.7 CDJ90565.1 - 0.0004 20.5 27.7 0.00043 20.5 11.4 2.4 2 0 0 2 2 2 1 Tropomyosin like IES5 PF17335.2 CDJ90565.1 - 0.024 14.9 2.5 0.024 14.9 2.5 2.5 2 0 0 2 2 2 0 Ino80 complex subunit 5 ATG16 PF08614.11 CDJ90565.1 - 0.068 13.4 31.3 0.25 11.5 31.1 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) MscS_porin PF12795.7 CDJ90565.1 - 0.2 11.2 25.4 0.29 10.6 25.4 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain ADIP PF11559.8 CDJ90565.1 - 0.77 9.8 29.5 1.5 8.9 15.6 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 CDJ90565.1 - 0.99 9.4 29.8 2 8.4 29.8 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.8 CDJ90565.1 - 1.2 9.2 20.2 0.035 14.1 11.1 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Golgin_A5 PF09787.9 CDJ90565.1 - 2.8 7.3 28.2 4.4 6.7 28.2 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 APG6_N PF17675.1 CDJ90565.1 - 3.6 8.1 35.7 14 6.2 34.2 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region UPF0242 PF06785.11 CDJ90565.1 - 3.8 7.6 30.1 0.71 9.9 19.6 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 CDJ90565.1 - 3.9 6.9 13.0 7.4 6.0 13.0 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_13 PF13166.6 CDJ90565.1 - 5.1 5.6 18.2 6.6 5.2 18.2 1.1 1 0 0 1 1 1 0 AAA domain DUF3450 PF11932.8 CDJ90565.1 - 6.5 6.0 23.3 1.5 8.1 15.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Jnk-SapK_ap_N PF09744.9 CDJ90565.1 - 6.7 6.9 34.9 5.1 7.3 27.2 2.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Laminin_II PF06009.12 CDJ90565.1 - 7.5 6.6 16.3 0.93 9.5 8.2 2.9 2 1 2 4 4 4 0 Laminin Domain II SAC3_GANP PF03399.16 CDJ90566.1 - 3.4e-67 226.9 21.5 1.1e-45 156.3 7.2 2.8 2 1 1 3 3 3 2 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 CDJ90566.1 - 0.022 14.8 0.1 0.05 13.6 0.1 1.6 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family AAA_23 PF13476.6 CDJ90566.1 - 3.1 8.2 6.0 2.9 8.3 3.4 2.2 2 0 0 2 2 2 0 AAA domain Globin PF00042.22 CDJ90567.1 - 2.7e-10 40.8 0.0 1.4e-09 38.5 0.0 2.0 2 0 0 2 2 2 1 Globin Protoglobin PF11563.8 CDJ90567.1 - 0.033 14.1 0.7 0.13 12.1 0.5 2.0 1 1 0 1 1 1 0 Protoglobin Peptidase_C65 PF10275.9 CDJ90567.1 - 0.066 12.6 0.2 0.3 10.5 0.0 1.9 2 0 0 2 2 2 0 Peptidase C65 Otubain BORCS7 PF16088.5 CDJ90567.1 - 0.096 12.9 0.1 0.35 11.2 0.0 1.8 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 Globin PF00042.22 CDJ90568.1 - 1.2e-17 64.4 0.0 1.9e-08 34.8 0.0 2.4 2 0 0 2 2 2 2 Globin Carbpep_Y_N PF05388.11 CDJ90568.1 - 1.2e-05 25.8 0.8 0.22 12.1 0.1 2.5 2 0 0 2 2 2 2 Carboxypeptidase Y pro-peptide Peptidase_C65 PF10275.9 CDJ90568.1 - 5.3e-05 22.8 1.4 0.15 11.5 0.1 2.4 2 0 0 2 2 2 2 Peptidase C65 Otubain DUF2508 PF10704.9 CDJ90568.1 - 0.0064 16.6 7.4 1.4 9.1 0.1 4.2 4 0 0 4 4 4 2 Protein of unknown function (DUF2508) DUF2524 PF10732.9 CDJ90568.1 - 0.0071 16.6 0.4 8.2 6.8 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2524) KaiA PF07688.12 CDJ90568.1 - 0.0078 16.4 0.2 0.9 9.7 0.0 2.7 2 0 0 2 2 2 1 KaiA C-terminal domain CEP1-DNA_bind PF09287.10 CDJ90568.1 - 0.02 14.6 1.0 4.3 6.9 0.1 2.3 2 0 0 2 2 2 0 CEP-1, DNA binding Ebp2 PF05890.12 CDJ90568.1 - 0.027 14.0 1.4 2.7 7.5 0.1 2.2 2 0 0 2 2 2 0 Eukaryotic rRNA processing protein EBP2 Dpoe2NT PF12213.8 CDJ90568.1 - 0.036 14.4 0.1 11 6.4 0.0 2.6 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal DUF1474 PF07342.11 CDJ90568.1 - 0.061 13.9 0.6 17 6.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) DUF600 PF04634.12 CDJ90568.1 - 0.063 13.3 1.4 3.2 7.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF600 BLYB PF05289.11 CDJ90568.1 - 0.091 13.0 0.4 17 5.7 0.0 2.6 2 0 0 2 2 2 0 Borrelia hemolysin accessory protein TcdB_N PF12918.7 CDJ90568.1 - 0.096 13.0 0.3 7.9 6.8 0.0 2.6 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain DUF1160 PF06648.11 CDJ90568.1 - 0.1 12.6 0.9 14 5.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1160) DUF3510 PF12022.8 CDJ90568.1 - 0.24 11.8 1.9 2.2 8.7 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) MRF_C1 PF13887.6 CDJ90568.1 - 0.29 10.3 2.1 0.56 9.4 0.1 2.2 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 KIP1 PF07765.12 CDJ90568.1 - 0.66 10.1 4.0 16 5.7 0.3 2.6 2 0 0 2 2 2 0 KIP1-like protein Globin PF00042.22 CDJ90569.1 - 4e-09 37.0 0.1 6.2e-09 36.4 0.1 1.3 1 0 0 1 1 1 1 Globin PhzC-PhzF PF02567.16 CDJ90571.1 - 9.7e-55 186.0 0.2 4e-54 184.0 0.2 1.8 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Helo_like_N PF17111.5 CDJ90572.1 - 0.032 13.6 0.1 0.039 13.3 0.1 1.2 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Sun2_CC2 PF18580.1 CDJ90573.1 - 0.034 14.4 0.1 0.1 12.9 0.0 1.8 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 zf-ZPR1 PF03367.13 CDJ90573.1 - 0.084 12.7 0.4 1.2 9.0 0.1 2.3 2 0 0 2 2 2 0 ZPR1 zinc-finger domain DZR PF12773.7 CDJ90573.1 - 0.83 9.7 4.2 1.6 8.8 0.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon Chromo PF00385.24 CDJ90574.1 - 8.9e-09 35.1 0.3 2.4e-08 33.7 0.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 CDJ90574.1 - 0.006 16.7 0.0 0.02 15.0 0.0 2.0 2 0 0 2 2 2 1 Chromo shadow domain Dehydrin PF00257.19 CDJ90574.1 - 0.03 14.9 1.4 0.03 14.9 1.4 2.2 2 0 0 2 2 2 0 Dehydrin Crinivirus_P26 PF07416.11 CDJ90574.1 - 0.09 12.5 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Crinivirus P26 protein Slu7 PF11708.8 CDJ90574.1 - 9.7 5.9 16.7 1.1e+02 2.4 16.7 2.1 1 1 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Hormone_recep PF00104.30 CDJ90576.1 - 6.6e-08 32.4 0.6 8e-08 32.1 0.6 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Dynactin PF12455.8 CDJ90577.1 - 8.2e-47 159.8 0.5 8.2e-47 159.8 0.5 3.5 2 1 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.25 CDJ90577.1 - 2.2e-23 82.1 0.6 3.7e-23 81.3 0.6 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF747 PF05346.11 CDJ90580.1 - 6.1e-106 354.5 18.3 7.8e-106 354.1 18.3 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family RhoGAP PF00620.27 CDJ90581.1 - 2e-35 121.9 0.0 3.1e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain 7TM_GPCR_Srt PF10321.9 CDJ90583.1 - 2.5e-53 181.1 17.3 2.8e-53 180.9 17.3 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt 7TM_GPCR_Srx PF10328.9 CDJ90583.1 - 1.1e-05 25.2 18.1 1.4e-05 24.9 18.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx StbA PF06406.11 CDJ90583.1 - 0.046 13.0 0.0 0.06 12.6 0.0 1.1 1 0 0 1 1 1 0 StbA protein Glyco_transf_92 PF01697.27 CDJ90584.1 - 1.5e-43 149.3 1.5 2e-43 148.9 1.5 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 QVR PF17064.5 CDJ90585.1 - 0.047 13.9 13.2 0.065 13.5 13.2 1.2 1 0 0 1 1 1 0 Sleepless protein 7TM_GPCR_Srab PF10292.9 CDJ90586.1 - 3.5e-08 32.7 3.3 3.9e-08 32.6 3.3 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Sra PF02117.16 CDJ90586.1 - 4.3e-05 22.5 5.8 5.2e-05 22.2 5.8 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sra DUF5391 PF17369.2 CDJ90586.1 - 0.0066 16.5 2.0 0.009 16.1 2.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5391) SLATT_4 PF18186.1 CDJ90586.1 - 0.047 13.3 1.8 2.3 7.8 0.3 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 Ycf70 PF17382.2 CDJ90586.1 - 0.047 14.1 0.0 0.065 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized Ycf70-like PRTase_1 PF11202.8 CDJ90586.1 - 0.077 12.2 0.3 0.16 11.2 0.1 1.5 1 1 0 1 1 1 0 Phosphoribosyl transferase (PRTase) 7TM_GPCR_Srab PF10292.9 CDJ90587.1 - 2.5e-30 105.5 4.5 2.8e-30 105.4 4.5 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Sra PF02117.16 CDJ90587.1 - 1.3e-11 43.9 8.6 1.6e-11 43.6 8.6 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sra 7TM_GPCR_Srb PF02175.16 CDJ90587.1 - 0.00029 20.7 2.3 0.00046 20.0 2.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srb P5-ATPase PF12409.8 CDJ90587.1 - 0.18 11.9 1.1 0.38 10.9 0.6 1.8 1 1 0 1 1 1 0 P5-type ATPase cation transporter BofA PF07441.11 CDJ90587.1 - 4.1 7.7 8.9 2.6 8.3 3.6 2.8 2 1 0 2 2 2 0 SigmaK-factor processing regulatory protein BofA Globin PF00042.22 CDJ90588.1 - 0.0074 16.8 0.0 0.011 16.3 0.0 1.3 1 0 0 1 1 1 1 Globin Gam PF06064.11 CDJ90588.1 - 0.054 13.7 1.3 0.4 11.0 0.1 2.5 2 1 1 3 3 3 0 Host-nuclease inhibitor protein Gam Ctr PF04145.15 CDJ90589.1 - 1.6e-24 87.2 9.3 1e-21 78.1 9.3 2.1 1 1 0 1 1 1 1 Ctr copper transporter family HTH_48 PF17906.1 CDJ90590.1 - 2.3e-15 56.4 1.0 5e-15 55.4 0.7 1.8 2 0 0 2 2 1 1 HTH domain in Mos1 transposase HTH_Tnp_IS630 PF01710.16 CDJ90590.1 - 1.6e-07 31.4 0.1 2.4e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 CDJ90590.1 - 4.9e-06 26.7 2.1 6.4e-06 26.3 0.6 1.9 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.6 CDJ90590.1 - 1.2e-05 25.0 0.9 0.053 13.3 0.0 2.8 3 0 0 3 3 2 2 Homeodomain-like domain HTH_38 PF13936.6 CDJ90590.1 - 3.1e-05 23.6 0.5 0.0001 22.0 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.6 CDJ90590.1 - 9.7e-05 22.9 1.9 0.00022 21.8 0.0 2.4 2 1 1 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 CDJ90590.1 - 0.0001 22.4 0.0 1 9.6 0.0 2.8 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_50 PF18024.1 CDJ90590.1 - 0.0007 19.2 0.0 0.0017 17.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 CDJ90590.1 - 0.0046 16.9 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_29 PF13551.6 CDJ90590.1 - 0.02 14.9 0.0 0.93 9.6 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn helix HTH_40 PF14493.6 CDJ90590.1 - 0.024 15.1 0.1 0.045 14.2 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain IF2_N PF04760.15 CDJ90590.1 - 0.03 14.1 0.0 0.084 12.7 0.0 1.8 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region HTH_36 PF13730.6 CDJ90590.1 - 0.067 13.2 0.0 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 CDJ90590.1 - 0.079 12.4 0.1 0.58 9.6 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 DUF1935 PF09149.10 CDJ90590.1 - 0.084 13.3 0.1 4.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1935) HTH_6 PF01418.17 CDJ90590.1 - 0.094 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Terminase_5 PF06056.12 CDJ90590.1 - 0.11 12.5 0.0 7.3 6.6 0.0 2.5 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) TubC_N PF18563.1 CDJ90590.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 TubC N-terminal docking domain HTH_5 PF01022.20 CDJ90590.1 - 0.12 12.3 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_10 PF04967.12 CDJ90590.1 - 0.12 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain NUMOD1 PF07453.13 CDJ90590.1 - 0.16 12.3 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 NUMOD1 domain V-ATPase_C PF03223.15 CDJ90591.1 - 1.5e-88 297.7 0.2 1.7e-88 297.5 0.2 1.0 1 0 0 1 1 1 1 V-ATPase subunit C MP PF01107.18 CDJ90591.1 - 0.064 12.8 0.1 0.087 12.4 0.1 1.3 1 0 0 1 1 1 0 Viral movement protein (MP) B9-C2 PF07162.11 CDJ90592.1 - 1.9e-36 125.8 0.5 2.7e-34 118.8 0.1 2.0 1 1 1 2 2 2 2 Ciliary basal body-associated, B9 protein Ets PF00178.22 CDJ90593.1 - 4.8e-35 119.9 0.7 7.2e-35 119.3 0.7 1.3 1 0 0 1 1 1 1 Ets-domain CAP_N PF01213.19 CDJ90593.1 - 6.3 6.2 12.3 0.14 11.6 3.3 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal LSDAT_euk PF18139.1 CDJ90594.1 - 3.2e-108 361.2 0.0 4.4e-108 360.7 0.0 1.2 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 CDJ90594.1 - 2.3e-18 66.2 0.0 4.1e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 CDJ90594.1 - 3.7e-16 59.1 19.0 5.3e-16 58.6 19.0 1.2 1 0 0 1 1 1 1 Ion transport protein TRPM_tetra PF16519.5 CDJ90594.1 - 0.00014 21.9 4.4 0.0003 20.8 4.4 1.6 1 0 0 1 1 1 1 Tetramerisation domain of TRPM Ctr PF04145.15 CDJ90594.1 - 0.029 15.0 0.1 0.029 15.0 0.1 3.2 3 1 0 3 3 3 0 Ctr copper transporter family RAP1 PF07218.11 CDJ90594.1 - 0.49 8.6 3.2 0.8 7.9 3.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) UL45 PF05473.12 CDJ90595.1 - 0.00014 21.5 0.0 0.00026 20.7 0.0 1.4 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Glyco_hydro_56 PF01630.18 CDJ90596.1 - 7.8e-15 54.7 0.0 1e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Hyaluronidase PP_kinase_C PF13090.6 CDJ90596.1 - 0.098 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 2 Glyco_hydro_56 PF01630.18 CDJ90597.1 - 3.5e-23 82.2 0.0 4.1e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 Hyaluronidase Glyco_hydro_56 PF01630.18 CDJ90598.1 - 2.4e-22 79.4 6.2 2.4e-20 72.8 1.8 2.0 1 1 1 2 2 2 2 Hyaluronidase Asp PF00026.23 CDJ90599.1 - 6.3e-50 170.4 1.2 4.4e-38 131.5 0.3 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ90599.1 - 1.9e-12 47.8 4.5 3.2e-11 43.8 4.4 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal UreD PF01774.17 CDJ90599.1 - 0.22 11.4 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 UreD urease accessory protein Asp PF00026.23 CDJ90600.1 - 1.9e-55 188.5 2.2 2.3e-55 188.3 2.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 CDJ90600.1 - 0.0017 18.2 0.0 0.013 15.3 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CDJ90600.1 - 0.1 13.2 0.1 0.86 10.3 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease Lig_chan-Glu_bd PF10613.9 CDJ90602.1 - 8.6e-42 142.0 0.0 1.7e-41 141.0 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 CDJ90602.1 - 4.1e-38 130.5 2.0 4.1e-38 130.5 2.0 1.6 2 0 0 2 2 2 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 CDJ90602.1 - 4.9e-11 42.5 0.0 1.6e-10 40.8 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 CDJ90602.1 - 1.5e-06 27.6 0.2 2.4e-06 26.9 0.2 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region CAP PF00188.26 CDJ90604.1 - 2.1e-11 44.7 1.5 3.2e-11 44.2 0.3 1.9 2 0 0 2 2 2 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ90604.1 - 0.022 15.0 0.1 0.071 13.4 0.1 1.9 1 1 0 1 1 1 0 Ancylostoma-associated secreted protein related Macoilin PF09726.9 CDJ90604.1 - 2.6 6.5 5.2 3.1 6.3 5.2 1.0 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 CDJ90604.1 - 9.1 4.4 7.5 12 4.0 7.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Guanylate_cyc PF00211.20 CDJ90605.1 - 6.5e-05 22.6 0.0 7.1e-05 22.5 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain STAT_bind PF02864.15 CDJ90607.1 - 9.9e-37 126.5 0.3 9.9e-37 126.5 0.3 1.7 2 0 0 2 2 2 1 STAT protein, DNA binding domain STAT_alpha PF01017.20 CDJ90607.1 - 2.4e-20 73.1 12.1 4.1e-20 72.4 12.1 1.3 1 0 0 1 1 1 1 STAT protein, all-alpha domain SH2 PF00017.24 CDJ90607.1 - 8.5e-06 25.8 0.0 2.3e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Tup_N PF08581.10 CDJ90607.1 - 0.00055 20.2 1.9 0.00055 20.2 1.9 2.5 2 1 0 2 2 2 1 Tup N-terminal FlxA PF14282.6 CDJ90607.1 - 0.063 13.3 2.6 0.22 11.5 2.6 1.9 1 0 0 1 1 1 0 FlxA-like protein Endonuclea_NS_2 PF13930.6 CDJ90607.1 - 0.14 12.2 2.9 3.4 7.8 0.1 2.4 2 0 0 2 2 2 0 DNA/RNA non-specific endonuclease AAA PF00004.29 CDJ90608.1 - 8.4e-43 146.0 0.0 1.4e-42 145.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ90608.1 - 4e-10 39.3 0.2 7.8e-10 38.4 0.2 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CDJ90608.1 - 6.9e-06 26.5 0.3 0.001 19.5 0.2 2.6 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CDJ90608.1 - 8e-06 26.2 0.9 0.0078 16.5 0.1 3.5 3 1 1 4 4 4 1 AAA domain AAA_2 PF07724.14 CDJ90608.1 - 0.00029 21.0 0.0 0.0011 19.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) NACHT PF05729.12 CDJ90608.1 - 0.00045 20.2 0.1 0.14 12.0 0.1 2.7 2 1 1 3 3 3 1 NACHT domain NB-ARC PF00931.22 CDJ90608.1 - 0.0028 16.9 0.0 0.039 13.1 0.1 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.6 CDJ90608.1 - 0.0034 17.6 0.0 0.0066 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CDJ90608.1 - 0.0036 17.8 0.0 0.01 16.4 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.6 CDJ90608.1 - 0.005 16.4 0.1 2 7.9 0.1 2.3 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 CDJ90608.1 - 0.017 14.8 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 CDJ90608.1 - 0.018 15.4 0.0 0.04 14.3 0.0 1.8 1 1 0 1 1 1 0 RNA helicase TIP49 PF06068.13 CDJ90608.1 - 0.02 14.1 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 CDJ90608.1 - 0.022 14.8 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CDJ90608.1 - 0.026 14.5 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 CDJ90608.1 - 0.028 14.3 0.7 0.7 9.8 0.2 2.4 2 1 0 2 2 2 0 Rad17 P-loop domain ATPase PF06745.13 CDJ90608.1 - 0.034 13.5 0.0 0.082 12.2 0.0 1.6 2 0 0 2 2 2 0 KaiC AAA_5 PF07728.14 CDJ90608.1 - 0.047 13.7 0.1 0.16 12.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CDJ90608.1 - 0.049 13.0 0.1 0.082 12.3 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CDJ90608.1 - 0.053 13.2 0.1 0.094 12.4 0.1 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.6 CDJ90608.1 - 0.097 13.2 0.1 0.29 11.7 0.1 1.9 1 1 1 2 2 2 0 AAA domain HTH_15 PF12324.8 CDJ90608.1 - 0.098 12.6 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase ATPase_2 PF01637.18 CDJ90608.1 - 0.12 12.3 0.0 0.7 9.8 0.0 2.0 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea DEAD PF00270.29 CDJ90608.1 - 0.14 12.0 0.0 15 5.3 0.1 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_7 PF12775.7 CDJ90608.1 - 0.22 11.0 0.1 0.41 10.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RabGAP-TBC PF00566.18 CDJ90609.1 - 5.2e-50 170.1 0.0 7.6e-50 169.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain BCL_N PF04714.13 CDJ90609.1 - 0.026 14.6 0.9 0.062 13.4 0.9 1.6 1 0 0 1 1 1 0 BCL7, N-terminal conserver region NARP1 PF12569.8 CDJ90610.1 - 5e-156 520.6 17.4 6.2e-139 464.2 0.4 3.3 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 Pkinase PF00069.25 CDJ90610.1 - 9e-57 192.4 0.2 8.1e-50 169.6 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ90610.1 - 4.5e-23 81.9 0.0 9.8e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_8 PF13181.6 CDJ90610.1 - 1e-14 53.4 16.1 0.0015 18.6 0.0 7.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ90610.1 - 1.4e-14 52.9 23.2 0.00027 20.8 0.1 8.4 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ90610.1 - 1.5e-12 46.8 17.4 0.0002 21.0 0.3 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ90610.1 - 8.6e-12 44.8 14.1 0.021 15.6 0.0 8.1 7 2 2 9 9 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ90610.1 - 1.1e-10 41.9 18.4 0.0037 17.7 0.8 6.2 5 1 2 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ90610.1 - 3.6e-10 39.4 8.9 2e-05 24.2 0.1 5.0 5 0 0 5 5 5 2 TPR repeat TPR_12 PF13424.6 CDJ90610.1 - 3.3e-09 36.9 13.9 0.98 9.8 0.1 7.8 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_15 PF13429.6 CDJ90610.1 - 7.4e-08 31.9 8.5 2.8e-05 23.5 1.5 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ90610.1 - 9.2e-08 32.6 9.3 0.052 14.2 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ90610.1 - 1.5e-05 25.0 5.1 0.0024 18.0 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ90610.1 - 3.6e-05 23.5 14.8 0.33 11.1 0.0 6.8 8 0 0 8 8 5 2 Tetratricopeptide repeat TPR_3 PF07720.12 CDJ90610.1 - 5.5e-05 23.1 3.1 0.52 10.4 0.3 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ90610.1 - 0.00044 20.7 14.7 1.6 9.5 0.0 6.0 6 0 0 6 6 4 2 Tetratricopeptide repeat Kdo PF06293.14 CDJ90610.1 - 0.0015 17.9 0.1 0.012 15.0 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family ANAPC3 PF12895.7 CDJ90610.1 - 0.0048 17.1 24.7 0.43 10.8 1.5 6.1 3 2 4 8 8 7 3 Anaphase-promoting complex, cyclosome, subunit 3 PRP3 PF08572.10 CDJ90610.1 - 0.0049 16.6 0.3 0.015 15.0 0.3 1.8 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) TPR_21 PF09976.9 CDJ90610.1 - 0.0087 15.8 0.0 0.0087 15.8 0.0 4.0 4 1 0 4 4 3 1 Tetratricopeptide repeat-like domain APH PF01636.23 CDJ90610.1 - 0.009 16.0 0.2 0.09 12.7 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family SPOR PF05036.13 CDJ90610.1 - 0.017 15.5 0.7 3.8 8.0 0.0 3.8 3 0 0 3 3 3 0 Sporulation related domain DUF3102 PF11300.8 CDJ90610.1 - 0.018 15.3 0.1 4.2 7.6 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3102) Kinase-like PF14531.6 CDJ90610.1 - 0.022 14.1 0.5 1.6 8.0 0.0 3.2 2 1 1 3 3 3 0 Kinase-like Pkinase_fungal PF17667.1 CDJ90610.1 - 0.024 13.4 0.3 0.057 12.2 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase PPR PF01535.20 CDJ90610.1 - 0.027 14.7 3.2 20 5.7 0.0 5.1 5 0 0 5 5 3 0 PPR repeat RIO1 PF01163.22 CDJ90610.1 - 0.029 14.0 0.2 0.13 11.9 0.0 2.2 2 0 0 2 2 1 0 RIO1 family TPR_17 PF13431.6 CDJ90610.1 - 0.034 14.5 10.7 71 4.1 0.0 7.6 8 0 0 8 8 7 0 Tetratricopeptide repeat UTRA PF07702.13 CDJ90610.1 - 0.1 12.5 0.0 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 UTRA domain PPR_1 PF12854.7 CDJ90610.1 - 0.22 11.3 1.5 35 4.2 0.1 3.4 3 0 0 3 3 3 0 PPR repeat TPR_10 PF13374.6 CDJ90610.1 - 0.23 11.4 12.6 11 6.1 0.1 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat DEAD_2 PF06733.15 CDJ90611.1 - 5.9e-46 156.3 1.5 1.2e-45 155.3 1.5 1.5 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 CDJ90611.1 - 1e-39 136.2 1.9 9.7e-35 120.0 0.4 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 CDJ90611.1 - 7.3e-07 29.5 1.1 1.9e-06 28.2 0.1 2.2 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 CDJ90611.1 - 1.3e-06 28.5 0.0 0.0059 16.6 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ90611.1 - 0.00037 20.3 0.1 1 9.1 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase SNF2_N PF00176.23 CDJ90611.1 - 0.0047 15.7 0.1 0.024 13.4 0.1 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Cast PF10174.9 CDJ90611.1 - 0.0078 14.5 0.5 0.011 14.1 0.5 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DUF2075 PF09848.9 CDJ90611.1 - 0.078 12.2 0.0 7.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 CDJ90611.1 - 0.082 12.7 0.4 0.28 10.9 0.4 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CDJ90611.1 - 0.18 12.1 0.3 39 4.5 0.1 2.9 2 1 1 3 3 3 0 AAA domain Collagen PF01391.18 CDJ90612.1 - 8.6e-20 70.3 86.5 3.2e-11 42.8 31.4 5.2 4 1 0 4 4 4 3 Collagen triple helix repeat (20 copies) G-alpha PF00503.20 CDJ90613.1 - 7.2e-121 403.7 7.0 8.4e-121 403.4 7.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDJ90613.1 - 8e-15 54.7 1.8 5.3e-11 42.3 0.1 3.0 3 1 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ90613.1 - 2.2e-05 23.9 0.9 0.0036 16.7 0.1 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region TniB PF05621.11 CDJ90613.1 - 0.004 16.6 0.0 0.0067 15.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein Roc PF08477.13 CDJ90613.1 - 0.0091 16.2 0.6 1.2 9.4 0.1 3.2 3 1 1 4 4 4 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 CDJ90613.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF503 PF04456.12 CDJ90613.1 - 0.076 12.9 0.4 1.2 9.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF503) HSP70 PF00012.20 CDJ90614.1 - 5.6e-262 870.3 15.7 6.4e-262 870.1 15.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CDJ90614.1 - 1.3e-21 76.7 1.7 1.9e-19 69.7 0.3 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CDJ90614.1 - 0.0012 19.2 6.7 0.92 10.0 0.1 3.7 3 2 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 CDJ90614.1 - 0.0037 16.6 0.5 0.08 12.2 0.1 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase DDR PF08841.10 CDJ90614.1 - 0.058 12.4 2.6 0.83 8.6 2.6 2.6 1 1 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 CDJ90614.1 - 0.15 11.7 0.0 0.38 10.4 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Goodbye PF17109.5 CDJ90614.1 - 8.1 6.9 10.0 5.9 7.4 0.3 3.3 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain Trehalase PF01204.18 CDJ90615.1 - 1.1e-40 140.0 0.3 1.2e-40 139.8 0.3 1.0 1 0 0 1 1 1 1 Trehalase TTR-52 PF01060.23 CDJ90617.1 - 1.7e-16 60.7 0.0 2.4e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Transthyretin-like family DUF3402 PF11882.8 CDJ90619.1 - 4.8e-79 266.6 12.5 2.9e-44 151.9 7.3 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.13 CDJ90619.1 - 5.4e-28 98.0 0.0 3.8e-27 95.2 0.0 2.4 2 1 0 2 2 2 1 N1221-like protein MeaB PF03308.16 CDJ90620.1 - 1.2e-86 290.1 0.1 1.4e-86 289.8 0.1 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 CDJ90620.1 - 0.00014 21.5 0.3 0.003 17.2 0.3 2.5 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 CDJ90620.1 - 0.00018 21.6 0.0 0.00098 19.2 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 CDJ90620.1 - 0.0004 20.9 0.3 0.0032 18.0 0.1 2.4 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 CDJ90620.1 - 0.0012 18.6 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 CDJ90620.1 - 0.0027 17.5 0.0 0.0049 16.7 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Thymidylate_kin PF02223.17 CDJ90620.1 - 0.025 14.2 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase RNA_helicase PF00910.22 CDJ90620.1 - 0.035 14.5 0.0 0.085 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF87 PF01935.17 CDJ90620.1 - 0.037 14.1 0.3 0.086 12.9 0.1 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain ABC_tran PF00005.27 CDJ90620.1 - 0.039 14.5 0.1 0.073 13.6 0.1 1.4 1 0 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.14 CDJ90620.1 - 0.043 13.0 0.0 0.077 12.2 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain CbiA PF01656.23 CDJ90620.1 - 0.044 13.9 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 CDJ90620.1 - 0.048 12.8 0.2 0.15 11.2 0.2 1.7 2 0 0 2 2 2 0 Anion-transporting ATPase AAA_30 PF13604.6 CDJ90620.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CDJ90620.1 - 0.078 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 CDJ90620.1 - 0.082 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 NTPase AAA PF00004.29 CDJ90620.1 - 0.094 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CDJ90620.1 - 0.11 12.7 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CDJ90620.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CDJ90620.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DNA_ligase_A_M PF01068.21 CDJ90621.1 - 7.2e-53 179.3 0.0 1.2e-52 178.6 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CDJ90621.1 - 3.8e-32 112.0 0.3 8.3e-32 110.9 0.3 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 CDJ90621.1 - 1.8e-17 63.7 0.0 7e-17 61.9 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region zf-PARP PF00645.18 CDJ90621.1 - 1.7e-14 54.4 0.0 9.2e-14 52.1 0.0 2.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-CCHH PF10283.9 CDJ90621.1 - 2.5e-10 40.2 6.0 6.3e-10 38.8 6.0 1.7 1 0 0 1 1 1 1 PBZ domain RNA_ligase PF09414.10 CDJ90621.1 - 1.1e-05 25.8 0.0 2.5e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 RNA ligase DNA_meth_N PF18284.1 CDJ90621.1 - 0.0073 16.2 0.7 0.09 12.7 0.7 2.5 1 1 0 1 1 1 1 DNA methylase N-terminal domain USP8_dimer PF08969.11 CDJ90621.1 - 1.4 9.2 5.2 0.39 10.9 0.5 2.6 3 0 0 3 3 3 0 USP8 dimerisation domain DDHD PF02862.17 CDJ90621.1 - 2 8.5 8.8 1 9.5 1.0 2.6 2 0 0 2 2 2 0 DDHD domain Neur_chan_memb PF02932.16 CDJ90621.1 - 9.5 6.2 13.3 1.9 8.5 3.9 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Aldedh PF00171.22 CDJ90623.1 - 1.1e-95 320.9 0.0 1.4e-95 320.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MDH PF02315.16 CDJ90623.1 - 0.15 12.1 0.1 0.69 10.0 0.1 2.0 2 0 0 2 2 2 0 Methanol dehydrogenase beta subunit Aldedh PF00171.22 CDJ90624.1 - 2.2e-96 323.2 0.0 2.7e-96 322.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TPR_14 PF13428.6 CDJ90625.1 - 3.3e-13 49.2 10.3 0.0024 18.6 0.1 5.2 2 1 4 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ90625.1 - 3.2e-11 43.6 5.4 5e-05 23.7 0.5 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ90625.1 - 2.2e-09 36.7 10.0 0.017 15.2 0.1 4.1 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ90625.1 - 2.5e-09 36.6 2.0 0.0025 17.9 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ90625.1 - 4.7e-08 33.5 7.8 0.013 16.1 0.3 3.4 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ90625.1 - 2.1e-07 30.5 2.2 0.0041 16.9 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ90625.1 - 1.8e-05 25.0 2.2 0.15 12.8 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ90625.1 - 0.00028 20.7 5.3 1.7 8.9 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TOM20_plant PF06552.12 CDJ90625.1 - 0.00033 20.5 0.2 0.071 12.9 0.1 3.0 1 1 1 3 3 3 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_11 PF13414.6 CDJ90625.1 - 0.00076 19.1 0.8 0.17 11.6 0.3 2.5 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.6 CDJ90625.1 - 0.0027 18.0 4.2 18 6.0 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 CDJ90625.1 - 0.0052 16.0 2.9 0.0096 15.2 2.6 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CDJ90625.1 - 0.014 15.9 1.5 0.96 9.9 0.1 2.3 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation ChAPs PF09295.10 CDJ90625.1 - 0.11 11.5 0.3 0.45 9.5 0.2 1.9 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.6 CDJ90625.1 - 0.13 12.4 5.8 5.4 7.2 0.6 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ90625.1 - 1.4 9.2 12.1 3.2 8.1 1.7 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ90625.1 - 3 7.8 6.8 2.2 8.3 0.3 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Glyco_transf_10 PF00852.19 CDJ90626.1 - 3.5e-44 150.6 0.2 5.7e-44 149.9 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CDJ90626.1 - 6.2e-17 62.1 0.2 2.4e-15 56.9 0.0 2.6 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Gp-FAR-1 PF05823.12 CDJ90628.1 - 1e-16 61.6 2.2 1.4e-16 61.2 2.2 1.1 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) p450 PF00067.22 CDJ90628.1 - 0.0078 15.0 0.1 0.015 14.1 0.1 1.3 1 1 0 1 1 1 1 Cytochrome P450 RdRP PF05183.12 CDJ90628.1 - 0.026 13.2 0.1 0.026 13.2 0.1 1.0 1 0 0 1 1 1 0 RNA dependent RNA polymerase Sigma70_r4 PF04545.16 CDJ90628.1 - 0.028 14.0 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 DUF520 PF04461.13 CDJ90628.1 - 0.031 14.4 0.1 0.057 13.5 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF520) DUF4404 PF14357.6 CDJ90628.1 - 0.033 14.8 1.0 0.32 11.7 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) Gal-bind_lectin PF00337.22 CDJ90629.1 - 6.8e-55 184.3 1.6 2.6e-28 98.2 0.1 2.1 2 0 0 2 2 2 2 Galactoside-binding lectin Alginate_lyase2 PF08787.11 CDJ90629.1 - 0.00052 19.9 0.2 0.12 12.2 0.0 2.2 2 0 0 2 2 2 2 Alginate lyase OLF PF02191.16 CDJ90629.1 - 0.15 11.6 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Olfactomedin-like domain Trypan_PARP PF05887.11 CDJ90630.1 - 0.048 13.6 12.2 0.093 12.7 12.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PPP4R2 PF09184.11 CDJ90630.1 - 2.2 7.8 19.3 3 7.4 19.3 1.2 1 0 0 1 1 1 0 PPP4R2 SAPS PF04499.15 CDJ90630.1 - 4 6.1 7.9 4.7 5.9 7.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.22 CDJ90630.1 - 7.2 5.7 7.4 11 5.1 7.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BUD22 PF09073.10 CDJ90630.1 - 8.7 5.6 25.7 11 5.2 25.7 1.1 1 0 0 1 1 1 0 BUD22 AMP-binding PF00501.28 CDJ90631.1 - 8.6e-99 331.0 0.0 1.1e-98 330.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ90631.1 - 5.7e-20 72.1 0.1 2e-19 70.4 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PH PF00169.29 CDJ90632.1 - 4.6e-10 40.0 1.2 7.1e-10 39.3 0.3 1.8 2 0 0 2 2 2 1 PH domain PH_17 PF18012.1 CDJ90632.1 - 0.003 17.3 0.0 0.0081 15.9 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 CDJ90632.1 - 0.013 15.9 0.3 0.031 14.7 0.3 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 CDJ90632.1 - 0.067 13.6 2.7 0.13 12.7 0.6 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain SH3_13 PF18335.1 CDJ90632.1 - 0.13 12.1 0.2 0.39 10.6 0.2 1.8 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain zf-Sec23_Sec24 PF04810.15 CDJ90632.1 - 0.17 11.9 1.4 2 8.6 0.0 2.5 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger TTR-52 PF01060.23 CDJ90634.1 - 1.7e-16 60.7 0.0 2.4e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Transthyretin-like family adh_short PF00106.25 CDJ90635.1 - 1.4e-08 34.5 1.5 1.7e-08 34.2 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase CLP1_P PF16575.5 CDJ90635.1 - 0.05 13.4 0.0 0.053 13.3 0.0 1.0 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop adh_short PF00106.25 CDJ90636.1 - 0.00099 18.6 0.0 0.0071 15.8 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ90636.1 - 0.003 17.1 0.0 0.0038 16.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CwfJ_C_1 PF04677.15 CDJ90637.1 - 0.022 14.6 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 DUF4690 PF15756.5 CDJ90638.1 - 0.17 12.5 0.2 0.29 11.8 0.2 1.4 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Iron_permease PF04120.12 CDJ90638.1 - 1.1 9.0 4.3 2.3 8.0 4.3 1.4 1 0 0 1 1 1 0 Low affinity iron permease Bromodomain PF00439.25 CDJ90639.1 - 9.8e-108 352.4 14.3 3.4e-20 71.9 0.0 6.6 6 0 0 6 6 6 6 Bromodomain BAH PF01426.18 CDJ90639.1 - 6.2e-29 100.3 0.1 1e-13 51.2 0.0 2.9 2 0 0 2 2 2 2 BAH domain HMG_box PF00505.19 CDJ90639.1 - 3.5e-11 43.4 0.3 3.5e-11 43.4 0.3 3.0 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ90639.1 - 1.3e-07 32.1 0.3 1.3e-07 32.1 0.3 2.3 2 0 0 2 2 2 1 HMG-box domain zf-C2H2_aberr PF17017.5 CDJ90639.1 - 0.00013 22.1 0.6 0.00013 22.1 0.6 2.0 2 0 0 2 2 2 1 Aberrant zinc-finger FOXP-CC PF16159.5 CDJ90639.1 - 0.016 15.9 2.9 0.17 12.5 0.5 3.0 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 CDJ90639.1 - 0.03 15.1 4.2 1.8 9.6 0.4 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger Ras PF00071.22 CDJ90640.1 - 2.6e-38 131.2 0.2 3.3e-38 130.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ90640.1 - 2.6e-28 98.7 0.0 4.7e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ90640.1 - 3e-10 39.8 0.1 3.7e-10 39.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ90640.1 - 0.00012 21.5 0.1 0.00015 21.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 CDJ90640.1 - 0.00087 19.1 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 CDJ90640.1 - 0.003 17.0 0.0 0.0044 16.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CDJ90640.1 - 0.048 13.2 0.1 7.3 6.1 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain XFP_N PF09364.10 CDJ90640.1 - 0.16 10.7 0.0 0.51 9.1 0.0 1.6 1 1 1 2 2 2 0 XFP N-terminal domain Y_phosphatase PF00102.27 CDJ90641.1 - 4.5e-63 213.0 0.7 7e-63 212.3 0.7 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ90641.1 - 0.0053 16.6 0.2 0.019 14.8 0.4 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CDJ90641.1 - 0.079 13.1 0.1 0.079 13.1 0.1 2.3 3 0 0 3 3 3 0 Inositol hexakisphosphate DUF4819 PF16090.5 CDJ90642.1 - 2.5e-07 30.7 0.1 1.5e-06 28.1 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4819) Helitron_like_N PF14214.6 CDJ90645.1 - 1.1e-58 198.7 0.0 1.3e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.13 CDJ90645.1 - 0.072 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) Laminin_EGF PF00053.24 CDJ90646.1 - 5.2e-06 26.5 35.1 0.14 12.3 1.7 4.5 1 1 3 4 4 4 4 Laminin EGF domain RCR PF12273.8 CDJ90646.1 - 0.014 16.0 0.3 0.014 16.0 0.3 2.0 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red EGF_2 PF07974.13 CDJ90646.1 - 0.015 15.6 35.2 0.54 10.7 2.2 4.8 5 0 0 5 5 5 0 EGF-like domain EGF_Tenascin PF18720.1 CDJ90646.1 - 0.63 10.2 29.3 0.06 13.4 4.5 4.8 3 1 1 4 4 4 0 Tenascin EGF domain GARS_A PF01071.19 CDJ90647.1 - 8.9e-69 231.2 0.0 1.8e-68 230.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Formyl_trans_N PF00551.19 CDJ90647.1 - 2.8e-48 164.1 0.1 4.8e-48 163.3 0.1 1.4 1 0 0 1 1 1 1 Formyl transferase GARS_N PF02844.15 CDJ90647.1 - 1.3e-29 102.8 0.0 4.5e-29 101.1 0.0 2.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 CDJ90647.1 - 1.5e-25 90.1 0.0 3.4e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 CDJ90647.1 - 2.2e-23 82.3 0.0 5.3e-23 81.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 CDJ90647.1 - 6.5e-11 42.7 1.3 1.7e-10 41.4 0.5 2.0 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp PF02222.22 CDJ90647.1 - 0.0004 20.0 0.0 0.00096 18.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.10 CDJ90647.1 - 0.095 12.2 0.1 0.32 10.5 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain ATPgrasp_ST PF14397.6 CDJ90647.1 - 0.12 11.6 0.0 0.28 10.4 0.0 1.6 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Usp PF00582.26 CDJ90647.1 - 0.14 12.7 0.4 26 5.3 0.0 3.5 3 0 0 3 3 3 0 Universal stress protein family Exo_endo_phos PF03372.23 CDJ90649.1 - 0.0014 18.2 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CDJ90649.1 - 0.0039 17.0 0.0 0.0083 16.0 0.0 1.6 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Recep_L_domain PF01030.24 CDJ90650.1 - 4.5e-08 33.2 0.1 1.6e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 Receptor L domain Recep_L_domain PF01030.24 CDJ90652.1 - 6e-05 23.1 0.0 7.8e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Receptor L domain PBP5_C PF07943.13 CDJ90653.1 - 1.2 9.4 7.0 14 6.0 0.1 3.5 3 0 0 3 3 3 0 Penicillin-binding protein 5, C-terminal domain Ribosomal_L22e PF01776.17 CDJ90654.1 - 9.5e-45 151.5 1.8 1.3e-44 151.1 1.8 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family Y_phosphatase PF00102.27 CDJ90655.1 - 2.4e-11 43.6 0.0 4.9e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDC27 PF09507.10 CDJ90655.1 - 6 6.1 34.4 8.2 5.7 34.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Paramyxo_ncap PF00973.19 CDJ90655.1 - 7.8 5.3 9.5 10 4.9 9.5 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Hormone_recep PF00104.30 CDJ90656.1 - 9.6e-25 87.4 0.0 1.5e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DUF2164 PF09932.9 CDJ90659.1 - 0.29 11.2 3.2 7.2 6.7 0.2 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2164) DUF148 PF02520.17 CDJ90660.1 - 1e-25 89.9 1.8 1.4e-25 89.5 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 DUF2833 PF11090.8 CDJ90660.1 - 0.21 12.0 0.3 1.5 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2833) BRE1 PF08647.11 CDJ90660.1 - 1.5 8.9 5.0 4.6 7.4 0.3 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF148 PF02520.17 CDJ90661.1 - 5.9e-18 65.0 1.1 7.6e-18 64.6 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF148 Njmu-R1 PF15053.6 CDJ90661.1 - 0.12 11.5 0.4 0.16 11.0 0.4 1.2 1 0 0 1 1 1 0 Mjmu-R1-like protein family Baculo_PEP_C PF04513.12 CDJ90661.1 - 0.18 11.8 0.0 0.36 10.9 0.0 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pre-PUA PF17832.1 CDJ90662.1 - 1.4e-23 83.4 0.1 2e-23 82.8 0.1 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 CDJ90662.1 - 2.5e-20 72.2 0.0 3.9e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 PUA domain RAP80_UIM PF18282.1 CDJ90662.1 - 0.016 15.0 0.3 0.026 14.3 0.3 1.3 1 0 0 1 1 1 0 RAP80 N-terminal ubiquitin interaction motif Q_salvage PF10343.9 CDJ90663.1 - 2.4e-99 332.5 0.0 2.9e-99 332.2 0.0 1.0 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family adh_short PF00106.25 CDJ90664.1 - 1.7e-14 53.7 0.0 3.3e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 CDJ90664.1 - 3.7e-08 33.1 0.0 4.9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 CDJ90664.1 - 5e-07 29.5 0.0 8.4e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 CDJ90664.1 - 0.00014 21.8 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CDJ90664.1 - 0.0019 17.7 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 CDJ90664.1 - 0.0024 17.1 0.0 0.059 12.5 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 CDJ90664.1 - 0.0039 17.1 0.0 0.0061 16.5 0.0 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 CDJ90664.1 - 0.012 14.7 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 CDJ90664.1 - 0.015 14.8 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.19 CDJ90664.1 - 0.024 13.7 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 CDJ90664.1 - 0.089 12.9 0.0 0.17 12.0 0.0 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 CDJ90664.1 - 0.16 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Prominin PF05478.11 CDJ90665.1 - 0.097 10.6 0.2 0.11 10.5 0.2 1.0 1 0 0 1 1 1 0 Prominin GAGA_bind PF06217.12 CDJ90666.1 - 0.22 11.7 7.2 0.26 11.5 7.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family CDC45 PF02724.14 CDJ90666.1 - 0.64 8.2 4.7 0.73 8.1 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4551 PF15087.6 CDJ90666.1 - 2 7.2 7.7 2.1 7.1 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RR_TM4-6 PF06459.12 CDJ90666.1 - 2.6 7.8 13.6 3.4 7.4 13.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 CDJ90666.1 - 7.4 4.6 7.8 8.4 4.4 7.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RAP1 PF07218.11 CDJ90666.1 - 8.3 4.6 11.0 11 4.2 11.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Cyclin_N PF00134.23 CDJ90667.1 - 2.2e-11 43.6 0.2 5.3e-11 42.4 0.2 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Afi1 PF07792.12 CDJ90667.1 - 0.96 9.9 3.4 2 8.9 3.4 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2828 PF11443.8 CDJ90667.1 - 1.4 6.9 6.1 1.9 6.5 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Macoilin PF09726.9 CDJ90667.1 - 1.6 7.2 7.0 2.2 6.7 7.0 1.1 1 0 0 1 1 1 0 Macoilin family E1-E2_ATPase PF00122.20 CDJ90668.1 - 9.2e-45 152.4 1.0 2.4e-44 151.0 1.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CDJ90668.1 - 2.2e-40 138.3 0.2 2.2e-40 138.3 0.2 3.0 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CDJ90668.1 - 2e-22 79.1 0.0 4e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CDJ90668.1 - 1.6e-21 77.6 0.1 4.8e-11 43.4 0.0 3.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CDJ90668.1 - 2.4e-16 59.2 0.0 4.3e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CDJ90668.1 - 8.3e-07 29.0 1.3 0.00069 19.4 0.7 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CDJ90668.1 - 0.00065 20.1 0.1 0.0053 17.2 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase MgtE PF01769.16 CDJ90668.1 - 0.48 10.8 8.6 9 6.7 6.8 2.7 2 0 0 2 2 2 0 Divalent cation transporter zf-RING_5 PF14634.6 CDJ90670.1 - 4.2 7.4 7.3 19 5.3 7.3 2.1 1 1 0 1 1 1 0 zinc-RING finger domain CPG4 PF15481.6 CDJ90672.1 - 2.1e-18 66.7 9.5 2.1e-18 66.7 9.5 2.4 2 1 0 2 2 2 1 Chondroitin proteoglycan 4 Pkinase PF00069.25 CDJ90673.1 - 8.5e-77 258.1 0.0 1e-76 257.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ90673.1 - 4.7e-36 124.4 0.0 6.5e-36 123.9 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ90673.1 - 5.2e-07 28.9 0.0 9.5e-06 24.8 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CDJ90673.1 - 0.00014 21.9 0.3 0.00032 20.7 0.3 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CDJ90673.1 - 0.0018 17.7 0.2 0.0035 16.7 0.2 1.6 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 CDJ90673.1 - 0.021 13.9 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Lectin_C PF00059.21 CDJ90674.1 - 4e-29 101.5 2.7 1.9e-14 54.3 0.5 2.4 2 0 0 2 2 2 2 Lectin C-type domain CUB PF00431.20 CDJ90674.1 - 5.1e-27 94.4 0.3 2.7e-17 63.1 0.1 2.4 2 0 0 2 2 2 2 CUB domain UL45 PF05473.12 CDJ90674.1 - 0.00049 19.8 2.2 0.0078 15.9 0.1 2.4 2 0 0 2 2 2 1 UL45 protein, carbohydrate-binding C-type lectin-like COE1_DBD PF16422.5 CDJ90674.1 - 0.07 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Transcription factor COE1 DNA-binding domain MCM_bind PF09739.9 CDJ90675.1 - 3.5e-68 230.5 0.0 1e-60 205.8 0.0 2.4 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor Ly-6_related PF06579.12 CDJ90676.1 - 5.5e-08 33.1 5.9 6.5e-08 32.9 5.4 1.4 1 1 0 1 1 1 1 Caenorhabditis elegans ly-6-related protein QVR PF17064.5 CDJ90676.1 - 0.069 13.4 13.8 21 5.4 13.8 3.0 1 1 0 1 1 1 0 Sleepless protein DUF4746 PF15928.5 CDJ90677.1 - 0.004 16.6 1.0 0.0055 16.2 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) DDE_3 PF13358.6 CDJ90678.1 - 1.4e-06 28.2 0.2 1.8e-06 27.8 0.2 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease RNase_PH PF01138.21 CDJ90679.1 - 1.9e-14 54.3 0.1 7.3e-14 52.4 0.1 1.8 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Ala_racemase_N PF01168.20 CDJ90680.1 - 9.2e-09 35.3 0.0 1e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF775 PF05603.12 CDJ90680.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF775) RT_RNaseH PF17917.1 CDJ90681.1 - 1.2e-30 105.9 0.0 3.7e-30 104.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ90681.1 - 4.3e-28 97.3 0.0 5e-27 93.9 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ90681.1 - 1.3e-14 54.0 0.4 3.6e-14 52.6 0.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDJ90681.1 - 1.4e-10 41.4 0.0 8.4e-10 38.9 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 CDJ90681.1 - 1.9e-10 40.6 0.0 3.2e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Laminin_EGF PF00053.24 CDJ90682.1 - 1.5e-110 361.2 258.5 1.2e-10 41.4 12.0 13.9 12 1 1 13 13 13 13 Laminin EGF domain Laminin_N PF00055.17 CDJ90682.1 - 1.5e-74 250.6 0.0 8e-74 248.2 0.0 2.4 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) Laminin_I PF06008.14 CDJ90682.1 - 0.00047 19.9 19.7 0.00047 19.9 19.7 3.8 2 1 1 4 4 4 1 Laminin Domain I F5_F8_type_C PF00754.25 CDJ90682.1 - 0.00067 19.8 0.0 0.0019 18.3 0.0 1.7 1 0 0 1 1 1 1 F5/8 type C domain T3SSipB PF16535.5 CDJ90682.1 - 0.0071 16.8 19.1 0.0071 16.8 19.1 4.9 2 2 1 4 4 4 1 Type III cell invasion protein SipB SNARE PF05739.19 CDJ90682.1 - 0.29 11.1 2.5 0.72 9.9 0.3 2.9 2 0 0 2 2 2 0 SNARE domain ZZ PF00569.17 CDJ90683.1 - 1.1e-11 44.3 6.3 1.1e-11 44.3 6.3 2.4 4 0 0 4 4 4 1 Zinc finger, ZZ type zf-Di19 PF05605.12 CDJ90683.1 - 1.5e-08 34.8 0.9 4.1e-08 33.4 0.9 1.8 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding EGF_2 PF07974.13 CDJ90684.1 - 0.00016 21.9 4.4 0.00016 21.9 4.4 5.0 4 1 1 5 5 5 1 EGF-like domain EGF PF00008.27 CDJ90684.1 - 0.00019 21.7 3.5 0.00019 21.7 3.5 4.6 3 2 0 3 3 3 2 EGF-like domain hEGF PF12661.7 CDJ90684.1 - 0.0022 18.5 15.2 0.12 13.0 0.9 5.2 4 1 0 4 4 4 2 Human growth factor-like EGF fn3 PF00041.21 CDJ90685.1 - 9.8e-07 29.0 0.4 4e-06 27.1 0.4 2.1 1 1 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CDJ90685.1 - 0.0029 18.2 0.0 0.0059 17.2 0.0 1.5 1 1 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 CDJ90685.1 - 0.067 13.5 0.0 0.092 13.1 0.0 1.2 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III Arylsulfotran_N PF17425.2 CDJ90685.1 - 0.14 12.2 0.0 0.38 10.8 0.0 1.8 1 1 0 1 1 1 0 Arylsulfotransferase Ig-like domain Glyco_hydro_36C PF16874.5 CDJ90685.1 - 0.14 12.6 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 36 C-terminal domain DUF5641 PF18701.1 CDJ90686.1 - 1.4e-13 50.8 0.1 4.5e-13 49.2 0.1 1.9 1 0 0 1 1 1 1 Family of unknown function (DUF5641) rve PF00665.26 CDJ90686.1 - 1.9e-12 47.4 0.0 4.4e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ90686.1 - 8.2e-10 38.6 0.4 2.8e-09 36.9 0.4 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CDJ90686.1 - 0.00077 19.6 0.4 0.00077 19.6 0.4 2.8 4 0 0 4 4 4 1 H2C2 zinc finger DUF1759 PF03564.15 CDJ90687.1 - 6.9e-21 74.7 1.8 2.2e-20 73.1 1.8 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 CDJ90687.1 - 2.4e-12 46.9 0.1 1.2e-11 44.7 0.0 2.2 2 0 0 2 2 2 1 Putative peptidase (DUF1758) RVT_1 PF00078.27 CDJ90687.1 - 6.8e-08 32.3 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CDJ90687.1 - 8.9e-06 26.3 0.3 3.3e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ90687.1 - 3.1e-05 24.4 0.0 0.00014 22.3 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ90687.1 - 0.01 15.6 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-C2H2_10 PF16588.5 CDJ90687.1 - 2.2 8.1 11.5 0.086 12.6 0.8 2.5 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 CDJ90687.1 - 3.8 7.4 12.6 2.8 7.8 1.8 2.6 2 0 0 2 2 2 0 Zinc knuckle Metallophos PF00149.28 CDJ90689.1 - 4.9e-06 27.2 1.5 6.8e-06 26.7 1.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1460 PF07313.12 CDJ90689.1 - 0.085 12.2 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) SOCS PF12610.8 CDJ90690.1 - 0.022 15.1 0.4 0.04 14.3 0.4 1.4 1 0 0 1 1 1 0 Suppressor of cytokine signalling Innexin PF00876.18 CDJ90691.1 - 1.2e-114 383.3 10.3 1.4e-114 383.1 10.3 1.0 1 0 0 1 1 1 1 Innexin Mem_trans PF03547.18 CDJ90691.1 - 0.2 10.0 0.0 0.2 10.0 0.0 1.7 2 0 0 2 2 2 0 Membrane transport protein EF-hand_10 PF14788.6 CDJ90692.1 - 5.7e-11 42.1 2.3 4.2e-10 39.3 0.6 2.7 2 1 1 3 3 3 1 EF hand EF-hand_6 PF13405.6 CDJ90692.1 - 1.7e-06 27.5 0.0 0.0022 17.8 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CDJ90692.1 - 3.5e-06 26.2 0.4 0.0027 17.1 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 CDJ90692.1 - 7.8e-06 25.2 0.0 0.00094 18.6 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 CDJ90692.1 - 8e-06 26.2 0.2 1.7e-05 25.2 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair PH PF00169.29 CDJ90692.1 - 3.1e-05 24.4 0.1 0.00065 20.2 0.0 2.2 2 0 0 2 2 2 1 PH domain EF-hand_8 PF13833.6 CDJ90692.1 - 4.8e-05 23.1 0.2 0.069 13.0 0.0 2.5 1 1 1 2 2 2 2 EF-hand domain pair PH_4 PF15404.6 CDJ90692.1 - 0.0036 17.1 0.4 0.012 15.4 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_12 PF16457.5 CDJ90692.1 - 0.0089 16.6 0.1 0.024 15.2 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain SPARC_Ca_bdg PF10591.9 CDJ90692.1 - 0.2 12.0 5.3 0.061 13.7 0.8 2.2 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region LRR_4 PF12799.7 CDJ90693.1 - 1.4e-06 28.6 9.2 0.02 15.3 2.5 5.4 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ90693.1 - 0.00032 20.4 8.6 1.2 8.9 2.0 5.1 5 0 0 5 5 5 3 Leucine rich repeat LRR_9 PF14580.6 CDJ90693.1 - 0.18 11.3 0.6 0.74 9.3 0.6 2.1 1 1 0 1 1 1 0 Leucine-rich repeat F-box PF00646.33 CDJ90694.1 - 0.062 13.2 1.4 0.2 11.6 0.2 2.4 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 CDJ90694.1 - 0.066 13.1 1.1 0.17 11.8 0.3 2.2 2 0 0 2 2 2 0 F-box-like HTH_Tnp_Tc3_2 PF01498.18 CDJ90696.1 - 2.2e-23 82.3 2.8 2.4e-23 82.1 1.1 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 CDJ90696.1 - 1.6e-14 53.9 0.0 3.4e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 CDJ90696.1 - 1.8e-09 38.0 6.9 3.4e-08 34.0 0.7 3.0 2 1 1 3 3 2 2 Homeodomain-like domain PAX PF00292.18 CDJ90696.1 - 1.6e-08 34.5 0.3 2.9e-08 33.7 0.3 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 CDJ90696.1 - 2.5e-07 30.3 1.1 3e-05 23.7 0.1 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 CDJ90696.1 - 1.7e-05 24.8 2.3 0.00024 21.1 0.4 2.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 CDJ90696.1 - 0.00013 22.0 0.6 0.011 15.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 CDJ90696.1 - 0.001 18.7 1.5 0.076 12.7 0.2 3.1 3 1 0 3 3 3 1 Sigma-70, region 4 MarR_2 PF12802.7 CDJ90696.1 - 0.0015 18.3 2.9 0.43 10.5 0.3 2.5 2 0 0 2 2 2 2 MarR family HTH_24 PF13412.6 CDJ90696.1 - 0.0021 17.6 3.2 1.8 8.2 1.0 3.3 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding CENP-B_N PF04218.13 CDJ90696.1 - 0.0042 16.7 0.1 1.1 8.9 0.0 2.5 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain Sigma70_r4 PF04545.16 CDJ90696.1 - 0.026 14.0 0.5 1.5 8.4 0.3 2.8 2 1 0 2 2 2 0 Sigma-70, region 4 HTH_12 PF08461.10 CDJ90696.1 - 0.026 14.5 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain GerE PF00196.19 CDJ90696.1 - 0.027 14.0 0.2 0.74 9.4 0.1 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_21 PF13276.6 CDJ90696.1 - 0.035 14.2 0.2 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 HTH-like domain TrmB PF01978.19 CDJ90696.1 - 0.048 13.5 0.0 0.44 10.5 0.0 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_38 PF13936.6 CDJ90696.1 - 0.21 11.4 3.9 0.23 11.3 0.5 2.6 2 1 1 3 3 3 0 Helix-turn-helix domain HTH_7 PF02796.15 CDJ90696.1 - 1.8 8.7 4.1 19 5.4 0.1 3.1 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase CLP_protease PF00574.23 CDJ90697.1 - 9e-61 204.9 0.2 1e-60 204.8 0.2 1.0 1 0 0 1 1 1 1 Clp protease ATP-synt_F PF01990.17 CDJ90698.1 - 5.2e-32 110.0 0.1 6.5e-32 109.7 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit HTH_48 PF17906.1 CDJ90700.1 - 2.1e-19 69.4 0.9 3.6e-19 68.6 0.9 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_Tnp_IS630 PF01710.16 CDJ90700.1 - 1.7e-05 24.8 0.0 2e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 CDJ90700.1 - 2.9e-05 23.7 0.0 0.16 11.8 0.0 2.4 2 0 0 2 2 2 2 Homeodomain-like domain HTH_38 PF13936.6 CDJ90700.1 - 3.1e-05 23.6 0.0 6.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 CDJ90700.1 - 0.00013 22.1 0.2 0.00067 19.9 0.1 1.9 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 CDJ90700.1 - 0.00026 21.5 0.0 0.00037 21.1 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 CDJ90700.1 - 0.00092 19.3 0.0 1.6 8.9 0.0 2.6 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_11 PF08279.12 CDJ90700.1 - 0.0053 16.7 0.0 0.009 15.9 0.0 1.4 1 0 0 1 1 1 1 HTH domain HTH_50 PF18024.1 CDJ90700.1 - 0.021 14.4 0.5 0.038 13.6 0.0 1.6 2 0 0 2 2 1 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 CDJ90700.1 - 0.025 14.9 0.1 6.1 7.2 0.0 2.2 1 1 1 2 2 2 0 Transposase IF2_N PF04760.15 CDJ90700.1 - 0.038 13.8 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Terminase_5 PF06056.12 CDJ90700.1 - 0.044 13.7 0.0 6.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_5 PF01022.20 CDJ90700.1 - 0.055 13.3 0.1 0.09 12.7 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family TnsD PF15978.5 CDJ90700.1 - 0.056 12.4 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_36 PF13730.6 CDJ90700.1 - 0.089 12.8 0.0 0.6 10.1 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_29 PF13551.6 CDJ90700.1 - 0.098 12.7 0.0 1.9 8.5 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn helix DUF4817 PF16087.5 CDJ90700.1 - 0.28 11.0 2.1 0.25 11.2 0.3 1.9 2 1 0 2 2 2 0 Helix-turn-helix domain (DUF4817) Sre PF03125.18 CDJ90701.1 - 2.3e-05 23.7 0.4 2.6e-05 23.5 0.4 1.0 1 0 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor 7TM_GPCR_Srab PF10292.9 CDJ90701.1 - 0.022 13.7 0.2 0.02 13.8 0.2 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor Hist_deacetyl PF00850.19 CDJ90702.1 - 3.4e-81 273.1 0.0 4.3e-81 272.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain ARID PF01388.21 CDJ90703.1 - 2e-17 63.6 0.1 6.5e-17 62.0 0.1 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain FOXP-CC PF16159.5 CDJ90703.1 - 8.1e-06 26.4 3.7 0.00034 21.2 1.2 4.0 3 1 1 4 4 4 2 FOXP coiled-coil domain RFX_DNA_binding PF02257.15 CDJ90703.1 - 9.1e-06 26.2 0.0 2.3e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain zf-C2H2_4 PF13894.6 CDJ90703.1 - 2.1 9.4 6.7 7.5 7.7 0.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Zip PF02535.22 CDJ90704.1 - 0.2 10.8 0.1 0.21 10.8 0.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Acyl_transf_3 PF01757.22 CDJ90705.1 - 3.3e-13 49.4 38.0 3.3e-13 49.4 38.0 1.8 2 0 0 2 2 2 1 Acyltransferase family DUF3054 PF11255.8 CDJ90705.1 - 0.091 13.3 1.3 0.27 11.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3054) RRM_1 PF00076.22 CDJ90706.1 - 4.4e-39 132.1 0.1 3.3e-19 68.5 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ90706.1 - 9.2e-06 25.3 0.1 0.036 13.7 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ90706.1 - 1.1e-05 25.5 0.1 0.0079 16.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif OB_RNB PF08206.11 CDJ90706.1 - 0.016 14.8 0.4 0.36 10.5 0.1 2.2 2 0 0 2 2 2 0 Ribonuclease B OB domain Cas_Cas2CT1978 PF09707.10 CDJ90706.1 - 0.085 12.9 0.0 9.6 6.4 0.0 2.2 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) Actin PF00022.19 CDJ90707.1 - 1.3e-70 238.0 0.0 2.7e-69 233.8 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CDJ90707.1 - 0.089 11.6 0.0 0.31 9.8 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein DUF2452 PF10504.9 CDJ90708.1 - 2.5e-55 186.2 0.1 3e-55 186.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) Tmemb_cc2 PF10267.9 CDJ90708.1 - 0.011 14.9 0.5 0.014 14.5 0.5 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Adaptin_binding PF10199.9 CDJ90708.1 - 0.54 10.9 2.8 1.1 9.8 2.8 1.6 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Tubulin PF00091.25 CDJ90709.1 - 2.1e-68 230.4 0.0 2.9e-68 230.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDJ90709.1 - 3.5e-50 169.4 0.0 6.8e-50 168.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CDJ90709.1 - 0.002 17.9 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain MSP PF01716.18 CDJ90709.1 - 0.087 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide LapA_dom PF06305.11 CDJ90710.1 - 0.6 10.0 4.4 0.9 9.4 4.5 1.3 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DZR PF12773.7 CDJ90711.1 - 0.004 17.1 0.3 0.0087 16.1 0.3 1.5 1 0 0 1 1 1 1 Double zinc ribbon Ribosomal_S27e PF01667.17 CDJ90711.1 - 0.0068 16.1 1.6 0.015 15.0 0.1 2.1 1 1 1 2 2 2 1 Ribosomal protein S27 zf-H2C2_2 PF13465.6 CDJ90711.1 - 0.062 13.7 0.3 0.062 13.7 0.3 2.6 3 0 0 3 3 3 0 Zinc-finger double domain C1_2 PF03107.16 CDJ90711.1 - 0.13 12.6 2.2 4.9 7.5 0.3 2.5 2 0 0 2 2 2 0 C1 domain zf-C2H2_4 PF13894.6 CDJ90711.1 - 3.8 8.6 7.1 30 5.8 2.3 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDJ90712.1 - 0.004 17.5 3.5 0.014 15.8 0.0 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 CDJ90712.1 - 2.9 8.5 4.9 61 4.4 1.2 3.3 2 1 0 2 2 2 0 Zinc finger, C2H2 type CCDC50_N PF15295.6 CDJ90713.1 - 9.8e-20 71.0 20.9 1.5e-19 70.4 20.9 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 50 N-terminus DUF5401 PF17380.2 CDJ90713.1 - 0.18 9.8 19.9 0.22 9.6 19.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF4407 PF14362.6 CDJ90713.1 - 0.45 9.8 5.2 0.57 9.5 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Methyltransf_32 PF13679.6 CDJ90713.1 - 1.2 9.1 3.5 1.6 8.7 2.9 1.5 1 1 0 1 1 1 0 Methyltransferase domain SUIM_assoc PF16619.5 CDJ90713.1 - 6.3 6.9 11.0 0.5 10.5 4.6 2.3 1 1 1 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Pkinase PF00069.25 CDJ90714.1 - 1.4e-43 149.1 0.0 2.5e-43 148.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 CDJ90714.1 - 9.2e-41 139.0 0.1 1.6e-40 138.2 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 CDJ90714.1 - 3e-27 95.5 0.0 6.5e-27 94.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ90714.1 - 1e-06 27.8 0.0 0.0018 17.1 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Kdo PF06293.14 CDJ90714.1 - 0.0013 18.2 0.1 0.0024 17.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ90714.1 - 0.0043 17.0 0.2 0.013 15.4 0.2 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family ASC PF00858.24 CDJ90715.1 - 2.1e-113 379.7 12.0 3e-113 379.1 12.0 1.3 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel TFIID-18kDa PF02269.16 CDJ90716.1 - 3.2e-15 55.9 0.3 6.4e-15 55.0 0.3 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit gpD PF02925.16 CDJ90716.1 - 0.16 12.0 0.1 0.42 10.6 0.1 1.7 2 1 0 2 2 2 0 Bacteriophage scaffolding protein D DUF202 PF02656.15 CDJ90717.1 - 1.8 9.1 9.4 0.74 10.3 2.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF2157 PF09925.9 CDJ90717.1 - 3.4 7.4 9.3 31 4.3 9.3 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF2142 PF09913.9 CDJ90717.1 - 6.9 5.4 10.3 0.34 9.7 3.8 1.9 1 1 2 3 3 3 0 Predicted membrane protein (DUF2142) IMS PF00817.20 CDJ90718.1 - 7e-45 152.7 0.1 1.1e-44 152.0 0.1 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 CDJ90718.1 - 1.3e-05 25.8 0.0 4.5e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 impB/mucB/samB family C-terminal domain Ribosomal_S8 PF00410.19 CDJ90719.1 - 7.8e-24 84.0 0.0 1e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 PRP38 PF03371.15 CDJ90721.1 - 1.2e-52 178.3 0.0 1.8e-52 177.7 0.0 1.3 1 0 0 1 1 1 1 PRP38 family CAP_GLY PF01302.25 CDJ90722.1 - 4.4e-14 52.2 1.9 9.5e-12 44.8 0.3 2.9 3 0 0 3 3 3 2 CAP-Gly domain ANAPC4_WD40 PF12894.7 CDJ90723.1 - 0.0059 16.9 0.0 2.7 8.3 0.0 3.2 2 2 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ90723.1 - 0.011 16.5 3.2 14 6.8 0.1 4.4 2 1 0 2 2 2 0 WD domain, G-beta repeat SNF2_N PF00176.23 CDJ90724.1 - 4e-79 265.9 1.2 7.3e-79 265.0 1.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ90724.1 - 8.7e-21 74.3 0.0 7.2e-20 71.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ90724.1 - 2.6e-12 47.1 0.1 1.3e-11 44.8 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ90724.1 - 1.2e-08 34.9 0.0 2.9e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 CDJ90724.1 - 4.1e-08 32.7 0.1 3.8e-07 29.6 0.0 2.3 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 CDJ90724.1 - 6.9e-05 22.6 0.1 0.00021 21.1 0.1 1.8 1 1 0 1 1 1 1 SWI2/SNF2 ATPase Pcc1 PF09341.10 CDJ90725.1 - 1.9e-11 43.9 0.5 2.6e-11 43.5 0.5 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 Lsr2 PF11774.8 CDJ90725.1 - 0.052 13.7 0.0 0.071 13.3 0.0 1.3 1 0 0 1 1 1 0 Lsr2 AAA_lid_10 PF17872.1 CDJ90725.1 - 0.06 13.5 0.2 6.4 7.0 0.0 2.1 1 1 1 2 2 2 0 AAA lid domain KASH_CCD PF14662.6 CDJ90726.1 - 0.00028 20.8 0.9 0.00028 20.8 0.9 8.0 4 1 4 8 8 8 1 Coiled-coil region of CCDC155 or KASH FadA PF09403.10 CDJ90726.1 - 0.025 15.1 2.8 0.025 15.1 2.8 9.3 4 1 6 10 10 10 0 Adhesion protein FadA LppA PF16708.5 CDJ90726.1 - 0.11 12.5 3.3 0.21 11.5 1.2 2.7 2 0 0 2 2 2 0 Lipoprotein confined to pathogenic Mycobacterium Cytochrome-c551 PF10643.9 CDJ90726.1 - 2.2 7.8 4.5 11 5.5 0.2 3.2 4 0 0 4 4 4 0 Photosystem P840 reaction-centre cytochrome c-551 MCU PF04678.13 CDJ90727.1 - 8.1e-61 205.2 1.2 1.1e-60 204.8 1.2 1.2 1 0 0 1 1 1 1 Mitochondrial calcium uniporter FARP PF01581.16 CDJ90728.1 - 0.0035 17.6 5.9 17 6.5 0.2 3.7 3 0 0 3 3 3 3 FMRFamide related peptide family RFamide_26RFa PF11109.8 CDJ90728.1 - 0.053 14.0 0.1 0.06 13.9 0.1 1.1 1 0 0 1 1 1 0 Orexigenic neuropeptide Qrfp/P518 MAM33 PF02330.16 CDJ90729.1 - 1.2e-09 38.4 0.0 1.6e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF3872 PF12988.7 CDJ90729.1 - 0.047 13.5 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3872) DEAD PF00270.29 CDJ90730.1 - 5.5e-16 58.8 0.0 1.1e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ90730.1 - 3.5e-11 43.4 0.0 1e-10 41.9 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDJ90730.1 - 1.9e-07 31.4 0.1 1.7e-06 28.3 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HBD PF18534.1 CDJ90730.1 - 0.13 12.4 0.0 0.45 10.7 0.0 1.9 1 0 0 1 1 1 0 Helical bundle domain SH3_2 PF07653.17 CDJ90731.1 - 4.8e-07 29.4 0.0 9e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDJ90731.1 - 3.1e-06 26.7 0.0 5.9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Guanylate_kin PF00625.21 CDJ90731.1 - 0.029 14.0 0.2 2.2 8.0 0.0 2.6 3 0 0 3 3 3 0 Guanylate kinase SH3_9 PF14604.6 CDJ90731.1 - 0.16 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain 7TM_GPCR_Srab PF10292.9 CDJ90732.1 - 1.7e-07 30.5 6.0 1.7e-07 30.5 6.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor SUR7 PF06687.12 CDJ90732.1 - 0.63 9.6 7.1 0.64 9.6 7.1 1.0 1 0 0 1 1 1 0 SUR7/PalI family 7TM_GPCR_Srab PF10292.9 CDJ90733.1 - 1.6e-32 112.7 9.7 2e-32 112.4 9.7 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Sra PF02117.16 CDJ90733.1 - 1.6e-12 46.9 12.7 1.8e-12 46.7 12.7 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sra TMEM138 PF14935.6 CDJ90733.1 - 4.1 8.1 10.7 2 9.1 1.8 2.4 2 0 0 2 2 2 0 Transmembrane protein 138 Lustrin_cystein PF14625.6 CDJ90734.1 - 0.00034 20.9 0.9 0.00061 20.1 0.9 1.5 1 0 0 1 1 1 1 Lustrin, cysteine-rich repeated domain Thioredoxin PF00085.20 CDJ90735.1 - 1.9e-16 59.9 0.1 2.9e-16 59.3 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 CDJ90735.1 - 6.4e-09 36.0 0.1 1.4e-06 28.4 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CDJ90735.1 - 0.00014 22.2 0.0 0.00025 21.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CDJ90735.1 - 0.0022 17.4 0.2 0.0036 16.7 0.2 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 CDJ90735.1 - 0.14 12.4 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin GpcrRhopsn4 PF10192.9 CDJ90736.1 - 5.2e-54 183.4 18.2 6.9e-54 183.0 18.2 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain cEGF PF12662.7 CDJ90737.1 - 5.6 7.0 9.5 64 3.6 9.5 2.7 1 1 0 1 1 1 0 Complement Clr-like EGF-like Thioredoxin_6 PF13848.6 CDJ90738.1 - 5.3e-42 143.8 4.1 1.3e-41 142.6 0.4 2.2 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin PF00085.20 CDJ90738.1 - 2.4e-16 59.6 0.2 1.1e-15 57.5 0.1 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 CDJ90738.1 - 2e-05 25.0 0.8 5.3e-05 23.6 0.1 2.1 1 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CDJ90738.1 - 0.0059 16.8 0.1 0.061 13.5 0.2 2.4 2 0 0 2 2 2 1 Thioredoxin-like UPF0164 PF03687.13 CDJ90738.1 - 0.2 10.5 0.0 0.3 9.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0164) FAM76 PF16046.5 CDJ90740.1 - 0.063 12.6 5.2 0.086 12.2 5.2 1.2 1 0 0 1 1 1 0 FAM76 protein GRP PF07172.11 CDJ90740.1 - 6.2 7.6 11.6 0.85 10.3 0.4 3.2 1 1 2 3 3 3 0 Glycine rich protein family LAT PF15234.6 CDJ90742.1 - 0.038 13.7 0.4 0.066 12.9 0.4 1.4 1 0 0 1 1 1 0 Linker for activation of T-cells DUF4131 PF13567.6 CDJ90742.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) EphA2_TM PF14575.6 CDJ90742.1 - 0.14 13.0 0.0 0.26 12.2 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Ly49 PF08391.10 CDJ90742.1 - 0.35 11.2 0.1 0.35 11.2 0.1 1.7 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Activin_recp PF01064.23 CDJ90743.1 - 0.0082 17.2 10.9 0.011 16.9 10.9 1.2 1 0 0 1 1 1 1 Activin types I and II receptor domain NUDIX PF00293.28 CDJ90744.1 - 7.2e-23 81.1 0.4 8e-23 80.9 0.4 1.0 1 0 0 1 1 1 1 NUDIX domain Lentiviral_Tat PF02998.14 CDJ90744.1 - 0.014 15.4 0.3 0.027 14.5 0.3 1.5 1 1 0 1 1 1 0 Lentiviral Tat protein RCC1 PF00415.18 CDJ90745.1 - 3.5e-35 120.4 1.6 1.8e-07 31.7 0.0 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ90745.1 - 2.9e-24 84.3 13.4 4.9e-05 23.0 0.0 7.8 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat AcetylCoA_hydro PF02550.15 CDJ90745.1 - 0.16 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase N-terminal domain vATP-synt_E PF01991.18 CDJ90746.1 - 2.4e-23 82.6 0.1 2.7e-23 82.4 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Salt_tol_Pase PF09506.10 CDJ90746.1 - 0.086 11.6 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) Sulfotransfer_2 PF03567.14 CDJ90747.1 - 7.5e-06 26.0 3.3 2.2e-05 24.5 0.3 2.0 1 1 1 2 2 2 1 Sulfotransferase family Ring_hydroxyl_A PF00848.19 CDJ90747.1 - 0.0015 18.5 0.2 0.0021 18.0 0.0 1.4 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Carbam_trans_N PF02543.15 CDJ90747.1 - 0.098 12.3 0.1 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus ARF7EP_C PF14949.6 CDJ90748.1 - 4.6e-26 91.5 6.3 4.6e-26 91.5 6.3 1.5 2 0 0 2 2 2 1 ARF7 effector protein C-terminus DUF4085 PF13315.6 CDJ90749.1 - 0.003 17.2 4.7 0.003 17.2 4.7 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF4085) PRESAN PF09687.10 CDJ90749.1 - 0.039 14.5 7.1 0.13 12.9 7.0 1.9 1 1 0 1 1 1 0 Plasmodium RESA N-terminal Prominin PF05478.11 CDJ90749.1 - 0.078 10.9 5.1 0.097 10.6 5.1 1.1 1 0 0 1 1 1 0 Prominin Fib_alpha PF08702.10 CDJ90749.1 - 0.15 12.3 13.4 0.57 10.4 13.4 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 CDJ90749.1 - 0.15 12.1 7.6 2 8.4 4.0 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3072 PF11272.8 CDJ90749.1 - 0.17 11.8 1.7 0.22 11.4 0.4 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF3072) Muted PF14942.6 CDJ90749.1 - 0.21 11.9 15.9 0.029 14.7 10.4 1.9 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein FapA PF03961.13 CDJ90749.1 - 0.25 9.9 10.8 0.33 9.5 10.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Fzo_mitofusin PF04799.13 CDJ90749.1 - 0.43 10.1 14.2 1.1 8.8 6.0 2.1 1 1 1 2 2 2 0 fzo-like conserved region DUF4735 PF15882.5 CDJ90749.1 - 0.46 9.9 4.6 0.37 10.2 1.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4735) tRNA-synt_His PF13393.6 CDJ90749.1 - 0.5 9.6 3.8 0.34 10.1 0.7 1.8 1 1 1 2 2 2 0 Histidyl-tRNA synthetase RmuC PF02646.16 CDJ90749.1 - 0.51 9.4 13.5 1.3 8.1 2.4 2.1 1 1 1 2 2 2 0 RmuC family PCRF PF03462.18 CDJ90749.1 - 0.52 10.2 12.7 1.1 9.1 12.7 1.5 1 1 0 1 1 1 0 PCRF domain Clusterin PF01093.17 CDJ90749.1 - 0.62 9.1 12.2 0.13 11.3 7.7 1.8 1 1 1 2 2 2 0 Clusterin Spore_III_AB PF09548.10 CDJ90749.1 - 0.64 10.1 8.8 0.058 13.5 2.9 1.8 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF1664 PF07889.12 CDJ90749.1 - 0.68 10.0 11.5 0.97 9.5 7.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1451 PF07295.11 CDJ90749.1 - 0.72 9.9 9.1 0.32 11.0 6.5 1.6 1 1 1 2 2 2 0 Zinc-ribbon containing domain ACP_PD PF04336.12 CDJ90749.1 - 0.74 10.3 5.0 2.6 8.5 0.7 2.2 1 1 1 2 2 2 0 Acyl carrier protein phosphodiesterase NPV_P10 PF05531.12 CDJ90749.1 - 0.86 10.1 9.7 1.2 9.6 5.1 2.7 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein NYD-SP28 PF14772.6 CDJ90749.1 - 1 9.5 17.1 3.1 7.9 2.8 2.1 1 1 1 2 2 2 0 Sperm tail DUF3347 PF11827.8 CDJ90749.1 - 1 9.5 8.9 0.18 12.0 2.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) CRR7 PF12095.8 CDJ90749.1 - 1.1 9.8 13.6 1.3 9.6 1.8 3.0 1 1 2 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 Exonuc_VII_L PF02601.15 CDJ90749.1 - 1.4 8.4 10.6 1.8 8.1 10.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DASH_Dam1 PF08653.10 CDJ90749.1 - 2 8.3 8.4 2 8.3 0.7 3.4 3 1 1 4 4 4 0 DASH complex subunit Dam1 OmpH PF03938.14 CDJ90749.1 - 2.5 8.4 17.8 1.2 9.5 9.2 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF1845 PF08900.11 CDJ90749.1 - 2.6 7.7 7.2 8.7 6.0 0.6 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF1845) LMBR1 PF04791.16 CDJ90749.1 - 2.9 6.7 6.9 3.5 6.4 6.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2203 PF09969.9 CDJ90749.1 - 5.5 7.7 9.9 3.5 8.4 4.1 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) TMPIT PF07851.13 CDJ90749.1 - 6.5 5.9 12.5 21 4.2 12.5 1.7 1 1 0 1 1 1 0 TMPIT-like protein EcsC PF12787.7 CDJ90749.1 - 8.6 6.0 9.5 25 4.4 9.4 1.7 1 1 0 1 1 1 0 EcsC protein family SLED PF12140.8 CDJ90750.1 - 7.6e-24 84.4 0.0 1.3e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 SLED domain SAM_1 PF00536.30 CDJ90750.1 - 0.00037 20.9 0.1 0.0023 18.3 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) MENTAL PF10457.9 CDJ90751.1 - 6.9e-48 162.8 4.5 1.1e-47 162.1 4.5 1.3 1 0 0 1 1 1 1 Cholesterol-capturing domain START PF01852.19 CDJ90751.1 - 2.1e-22 79.6 0.6 5.6e-22 78.2 0.0 1.9 2 0 0 2 2 2 1 START domain zf-Di19 PF05605.12 CDJ90751.1 - 0.0034 17.6 4.5 0.019 15.3 4.5 2.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C3Hc3H PF13891.6 CDJ90751.1 - 0.082 13.3 1.5 6.9 7.1 0.1 3.2 2 0 0 2 2 2 0 Potential DNA-binding domain zf-C2H2_4 PF13894.6 CDJ90751.1 - 6.2 7.9 11.1 26 6.0 0.6 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger Actin PF00022.19 CDJ90752.1 - 6.7e-42 143.5 0.0 3.1e-40 138.0 0.0 2.7 1 1 0 1 1 1 1 Actin Acyltransferase PF01553.21 CDJ90753.1 - 9.7e-13 47.9 0.0 4.5e-12 45.7 0.0 2.0 2 0 0 2 2 2 1 Acyltransferase Glyco_hydro_18 PF00704.28 CDJ90754.1 - 3.3e-59 201.2 0.0 3.2e-26 92.8 0.0 3.7 3 1 0 3 3 3 3 Glycosyl hydrolases family 18 Peptidase_S7 PF00949.21 CDJ90754.1 - 0.088 12.6 0.0 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease XisI PF08869.11 CDJ90754.1 - 0.13 12.6 0.0 30 5.0 0.0 2.4 2 0 0 2 2 2 0 XisI protein PIF1 PF05970.14 CDJ90756.1 - 2.5e-98 329.6 0.0 3.4e-98 329.2 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 CDJ90756.1 - 6.2e-37 127.7 0.0 1.6e-36 126.3 0.0 1.8 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 CDJ90756.1 - 3.9e-12 46.3 0.0 6.8e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 CDJ90756.1 - 3.4e-06 25.3 0.0 6.6e-06 24.3 0.0 1.4 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 CDJ90756.1 - 6.1e-06 26.0 0.0 1.6e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 CDJ90756.1 - 7e-06 26.4 0.0 1.9e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CDJ90756.1 - 0.0005 19.9 0.0 0.11 12.2 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 CDJ90756.1 - 0.00097 18.9 0.1 0.015 15.1 0.1 2.3 1 1 0 1 1 1 1 IstB-like ATP binding protein ResIII PF04851.15 CDJ90756.1 - 0.0099 15.9 0.0 0.047 13.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NB-ARC PF00931.22 CDJ90756.1 - 0.013 14.7 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 CDJ90756.1 - 0.041 14.3 0.1 0.6 10.5 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 CDJ90756.1 - 0.05 13.9 0.0 0.23 11.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 CDJ90756.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Laminin_EGF PF00053.24 CDJ90757.1 - 0.0034 17.5 6.8 0.11 12.7 6.8 2.3 1 1 0 1 1 1 1 Laminin EGF domain zf-C2H2 PF00096.26 CDJ90759.1 - 6.8e-13 48.3 28.4 6.8e-06 26.3 1.6 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ90759.1 - 2.1e-10 40.5 31.5 0.0073 17.1 2.1 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ90759.1 - 3.8e-07 30.2 13.1 0.0002 21.5 1.7 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 CDJ90759.1 - 2.4e-05 24.1 14.2 0.28 11.1 0.3 4.5 4 0 0 4 4 4 4 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 CDJ90759.1 - 0.00046 20.1 31.4 0.041 13.9 2.1 4.5 4 1 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 CDJ90759.1 - 0.00052 20.3 17.9 0.0021 18.4 1.6 4.8 5 0 0 5 5 5 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 CDJ90759.1 - 0.0029 17.9 27.6 2.4 8.7 3.2 5.1 4 1 0 4 4 4 3 Zinc-finger double domain ADK_lid PF05191.14 CDJ90759.1 - 0.048 13.6 7.0 2.5 8.1 0.3 3.1 2 1 0 2 2 2 0 Adenylate kinase, active site lid XPA_N PF01286.18 CDJ90759.1 - 0.38 10.9 0.3 0.38 10.9 0.3 3.2 4 0 0 4 4 4 0 XPA protein N-terminal zf-C2H2_11 PF16622.5 CDJ90759.1 - 2 8.3 24.8 1.7 8.5 0.6 4.4 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 CDJ90759.1 - 7.3 7.0 17.6 1.9 8.9 0.1 3.7 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-AN1 PF01428.16 CDJ90759.1 - 7.6 6.8 18.7 12 6.2 1.2 4.2 4 0 0 4 4 4 0 AN1-like Zinc finger zf_UBZ PF18439.1 CDJ90759.1 - 9.3 5.9 15.3 2.2 7.9 0.4 4.2 4 1 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Macoilin PF09726.9 CDJ90760.1 - 5.1 5.5 39.5 6.3 5.2 39.5 1.2 1 0 0 1 1 1 0 Macoilin family RVT_1 PF00078.27 CDJ90762.1 - 7e-15 55.1 0.0 7.6e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APO_RNA-bind PF05634.11 CDJ90762.1 - 0.13 11.6 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 APO RNA-binding Y_phosphatase PF00102.27 CDJ90763.1 - 3.2e-69 233.1 0.2 4.3e-69 232.7 0.2 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ90763.1 - 5.4e-07 29.5 0.0 1.8e-06 27.8 0.1 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDJ90763.1 - 0.00021 21.3 0.3 0.0021 18.1 0.0 2.3 2 1 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CDJ90763.1 - 0.04 14.0 1.4 0.16 12.1 0.1 2.5 3 0 0 3 3 3 0 Inositol hexakisphosphate RRM_1 PF00076.22 CDJ90764.1 - 0.01 15.6 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PET PF06297.14 CDJ90765.1 - 1.3e-33 115.1 0.1 2.4e-33 114.3 0.1 1.4 1 0 0 1 1 1 1 PET Domain LIM PF00412.22 CDJ90765.1 - 2.2e-11 43.8 5.1 2.2e-11 43.8 5.1 2.4 2 0 0 2 2 2 1 LIM domain Prok-RING_1 PF14446.6 CDJ90765.1 - 0.004 17.1 3.2 0.004 17.1 3.2 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHF5 PF03660.14 CDJ90765.1 - 0.15 12.3 7.4 5.5 7.2 3.1 2.3 2 0 0 2 2 2 0 PHF5-like protein Prot_inhib_II PF02428.15 CDJ90765.1 - 1.1 9.7 11.3 0.93 10.0 1.9 2.8 1 1 1 2 2 2 0 Potato type II proteinase inhibitor family Integrase_H2C2 PF17921.1 CDJ90767.1 - 0.0031 17.6 0.1 0.093 12.9 0.0 2.7 2 0 0 2 2 2 1 Integrase zinc binding domain DUF5641 PF18701.1 CDJ90768.1 - 2.7e-16 59.5 0.5 4.7e-16 58.7 0.5 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5641) rve PF00665.26 CDJ90768.1 - 1.6e-11 44.5 0.0 3.1e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDJ90768.1 - 0.0023 17.6 0.1 0.015 15.1 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Peptidase_A17 PF05380.13 CDJ90769.1 - 3.2e-30 105.3 0.2 4.9e-22 78.6 0.0 2.9 2 1 1 3 3 3 2 Pao retrotransposon peptidase DUF1758 PF05585.12 CDJ90769.1 - 5.8e-09 35.9 0.1 2e-08 34.2 0.1 1.8 1 1 0 1 1 1 1 Putative peptidase (DUF1758) RVT_1 PF00078.27 CDJ90769.1 - 3.3e-06 26.8 0.0 7.2e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CDJ90769.1 - 0.00093 19.8 0.2 0.0033 18.0 0.2 1.9 1 1 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.8 CDJ90769.1 - 0.0011 18.5 0.3 0.0026 17.3 0.3 1.5 1 0 0 1 1 1 1 Ty3 transposon peptidase gag-asp_proteas PF13975.6 CDJ90769.1 - 0.0017 18.9 0.1 0.0047 17.5 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ90769.1 - 0.0028 17.4 0.1 0.0066 16.2 0.1 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF4835 PF16119.5 CDJ90769.1 - 0.041 13.0 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4835) RVT_3 PF13456.6 CDJ90769.1 - 0.12 12.2 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like Pkinase PF00069.25 CDJ90770.1 - 2.4e-37 128.8 0.0 5.8e-37 127.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ90770.1 - 3.5e-37 128.1 0.0 5.2e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.12 CDJ90770.1 - 9.4e-08 31.4 0.5 2e-07 30.4 0.5 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif EMP24_GP25L PF01105.24 CDJ90771.1 - 1e-31 110.3 0.0 1.3e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ComJ PF11033.8 CDJ90771.1 - 0.089 12.5 0.0 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 Competence protein J (ComJ) EMP24_GP25L PF01105.24 CDJ90772.1 - 6.5e-06 26.2 0.0 7.8e-06 26.0 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EMP24_GP25L PF01105.24 CDJ90773.1 - 3.2e-13 50.0 0.0 3.8e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD V-ATPase_H_N PF03224.14 CDJ90774.1 - 1.6e-95 320.1 8.5 2.6e-95 319.4 7.9 1.7 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 CDJ90774.1 - 4.7e-46 155.7 0.6 1.9e-44 150.5 0.0 3.3 3 0 0 3 3 3 1 V-ATPase subunit H PseudoU_synth_1 PF01416.20 CDJ90774.1 - 4e-12 46.5 0.1 1.1e-09 38.7 0.0 2.9 2 0 0 2 2 2 1 tRNA pseudouridine synthase Arm PF00514.23 CDJ90774.1 - 0.00014 21.7 0.3 7.6 6.7 0.1 4.7 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 CDJ90774.1 - 0.00065 19.2 1.9 0.025 14.1 0.0 2.5 2 0 0 2 2 2 1 Armadillo-like HEAT_2 PF13646.6 CDJ90774.1 - 0.00065 20.0 0.5 0.023 15.1 0.0 3.7 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.22 CDJ90774.1 - 0.067 13.5 0.4 0.51 10.7 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat DUF2326 PF10088.9 CDJ90774.1 - 0.12 12.1 4.0 0.25 11.1 0.1 3.4 3 1 1 4 4 4 0 Uncharacterised protein conserved in bacteria (DUF2326) Cyt-b5 PF00173.28 CDJ90774.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain DUF913 PF06025.12 CDJ90774.1 - 3.3 6.6 6.1 0.48 9.3 0.0 2.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) Prenyltransf PF01255.19 CDJ90775.1 - 0.0051 16.4 0.0 0.23 11.0 0.0 2.1 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase RVT_1 PF00078.27 CDJ90776.1 - 4.1e-10 39.5 0.1 2e-09 37.3 0.1 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GSCFA PF08885.11 CDJ90776.1 - 0.03 14.0 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 GSCFA family Neur_chan_memb PF02932.16 CDJ90777.1 - 0.00013 22.1 0.0 0.019 15.0 0.0 2.0 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S10 PF00450.22 CDJ90778.1 - 5.8e-75 253.3 2.7 1.7e-49 169.3 1.8 2.0 1 1 1 2 2 2 2 Serine carboxypeptidase Peptidase_S10 PF00450.22 CDJ90779.1 - 1.5e-75 255.2 3.0 1.6e-49 169.4 2.4 2.2 1 1 1 2 2 2 2 Serine carboxypeptidase RVT_1 PF00078.27 CDJ90780.1 - 2.5e-38 131.8 0.0 3.4e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_S10 PF00450.22 CDJ90781.1 - 5.3e-76 256.7 7.8 4e-35 122.0 0.0 3.0 1 1 2 3 3 3 3 Serine carboxypeptidase TTR-52 PF01060.23 CDJ90782.1 - 3.9e-22 78.7 0.1 7.4e-22 77.8 0.0 1.4 2 0 0 2 2 2 1 Transthyretin-like family SRP72 PF08492.12 CDJ90782.1 - 0.2 12.1 0.0 0.24 11.8 0.0 1.3 1 1 0 1 1 1 0 SRP72 RNA-binding domain TTR-52 PF01060.23 CDJ90783.1 - 1e-26 93.4 0.0 1.9e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 Transthyretin-like family TTR-52 PF01060.23 CDJ90784.1 - 5.8e-27 94.2 0.0 8.6e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Transthyretin-like family SRP72 PF08492.12 CDJ90784.1 - 0.17 12.3 0.1 0.23 11.9 0.1 1.3 1 1 0 1 1 1 0 SRP72 RNA-binding domain zf-UBR PF02207.20 CDJ90785.1 - 9.3e-18 64.2 9.7 9.3e-18 64.2 9.7 2.6 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Orf78 PF06024.12 CDJ90786.1 - 0.31 11.4 1.0 3.9 7.8 1.0 2.3 2 0 0 2 2 2 0 Orf78 (ac78) ABC2_membrane_3 PF12698.7 CDJ90786.1 - 1.3 8.1 10.3 2.7 7.0 0.6 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein MFS_1 PF07690.16 CDJ90787.1 - 2.7e-18 66.0 45.6 2.4e-17 62.9 35.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PIRT PF15099.6 CDJ90787.1 - 0.079 12.5 3.5 0.22 11.1 0.1 2.6 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family DUF5353 PF17304.2 CDJ90787.1 - 0.44 10.3 4.3 0.71 9.7 0.1 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5353) APG6_N PF17675.1 CDJ90788.1 - 0.0011 19.5 0.7 0.0011 19.5 0.7 3.6 3 1 0 3 3 3 1 Apg6 coiled-coil region zf-C3H1 PF10650.9 CDJ90788.1 - 0.0049 16.6 0.3 0.01 15.5 0.3 1.6 1 0 0 1 1 1 1 Putative zinc-finger domain DUF16 PF01519.16 CDJ90788.1 - 0.55 10.8 3.4 2 8.9 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 3Beta_HSD PF01073.19 CDJ90789.1 - 6.1e-14 51.7 0.0 8.1e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CDJ90789.1 - 2.6e-10 40.2 0.0 4.2e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CDJ90789.1 - 3.7e-06 27.0 0.0 5.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 CDJ90789.1 - 0.19 10.8 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 CDJ90790.1 - 6.7e-40 136.6 3.2 6.7e-40 136.6 3.2 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ90790.1 - 5e-31 108.1 2.1 1e-30 107.0 2.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.17 CDJ90790.1 - 1.5e-20 73.6 0.3 3.3e-20 72.5 0.3 1.6 1 0 0 1 1 1 1 SCP-2 sterol transfer family KR PF08659.10 CDJ90790.1 - 1e-16 61.4 1.6 2.3e-16 60.2 1.6 1.5 1 0 0 1 1 1 1 KR domain Alkyl_sulf_C PF14864.6 CDJ90790.1 - 8.7e-07 29.3 0.1 2.1e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Exo_endo_phos PF03372.23 CDJ90790.1 - 0.011 15.3 0.0 0.023 14.2 0.0 1.6 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family TTR-52 PF01060.23 CDJ90791.1 - 1.1e-24 86.9 0.1 1.4e-24 86.6 0.1 1.1 1 0 0 1 1 1 1 Transthyretin-like family TUDOR PF00567.24 CDJ90792.1 - 2.8e-09 37.0 0.0 4.4e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Tudor domain TAF1D PF15333.6 CDJ90792.1 - 0.081 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D ThrE PF06738.12 CDJ90792.1 - 0.19 11.1 0.0 0.37 10.1 0.0 1.5 1 1 0 1 1 1 0 Putative threonine/serine exporter TTR-52 PF01060.23 CDJ90793.1 - 7.7e-24 84.2 0.1 1.1e-23 83.8 0.1 1.2 1 0 0 1 1 1 1 Transthyretin-like family bMG3 PF11974.8 CDJ90793.1 - 0.035 14.1 0.0 0.048 13.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain Transthyretin PF00576.21 CDJ90793.1 - 0.1 13.3 0.0 0.21 12.3 0.0 1.4 1 1 0 1 1 1 0 HIUase/Transthyretin family Ribosomal_L11_N PF03946.14 CDJ90795.1 - 3e-24 84.6 0.1 6.3e-24 83.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CDJ90795.1 - 2e-21 76.3 0.1 4.4e-21 75.1 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Glycos_transf_2 PF00535.26 CDJ90796.1 - 5.8e-31 107.6 0.0 9.2e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CDJ90796.1 - 2e-15 57.1 3.7 4.7e-15 56.0 3.3 1.8 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 CDJ90796.1 - 2e-07 30.5 0.0 6e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CDJ90796.1 - 5.2e-05 22.9 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 AMP-binding PF00501.28 CDJ90797.1 - 5.7e-27 94.4 0.0 6.8e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ90797.1 - 7.8e-18 65.2 0.1 1.7e-17 64.2 0.1 1.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Herpes_DNAp_acc PF04929.12 CDJ90798.1 - 0.87 8.5 8.1 1.1 8.1 8.1 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Pet191_N PF10203.9 CDJ90799.1 - 2.4e-23 82.2 5.5 2.9e-23 81.9 5.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 CDJ90799.1 - 0.00025 21.0 3.0 0.25 11.4 0.4 2.4 1 1 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 CDJ90799.1 - 0.0021 18.1 1.0 0.14 12.4 0.3 2.3 2 0 0 2 2 2 1 CHCH domain DUF692 PF05114.13 CDJ90799.1 - 0.15 11.3 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF692) Cmc1 PF08583.10 CDJ90799.1 - 0.39 10.8 5.6 4.2 7.5 2.1 2.5 1 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Mic1 PF07035.12 CDJ90800.1 - 6.5e-39 133.2 2.1 1.9e-38 131.6 2.1 1.8 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like IKI3 PF04762.12 CDJ90800.1 - 0.0081 14.2 0.0 0.016 13.2 0.0 1.4 1 1 0 1 1 1 1 IKI3 family DUF5071 PF16804.5 CDJ90800.1 - 0.061 13.6 0.7 0.16 12.3 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5071) zf-ANAPC11 PF12861.7 CDJ90801.1 - 6.8e-32 109.4 12.2 9.2e-32 109.0 12.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CDJ90801.1 - 7.6e-19 67.8 18.1 1.2e-18 67.2 18.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CDJ90801.1 - 0.00014 22.2 23.8 0.0029 17.9 23.8 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CDJ90801.1 - 0.14 12.0 16.7 0.38 10.7 16.7 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ90801.1 - 0.8 9.7 18.4 6.1 6.9 19.0 2.0 1 1 1 2 2 2 0 zinc-RING finger domain WGG PF10273.9 CDJ90802.1 - 2.1e-14 53.9 0.1 4.1e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 STAT_bind PF02864.15 CDJ90803.1 - 9.9e-37 126.5 0.3 9.9e-37 126.5 0.3 1.7 2 0 0 2 2 2 1 STAT protein, DNA binding domain STAT_alpha PF01017.20 CDJ90803.1 - 2.4e-20 73.1 12.1 4.1e-20 72.4 12.1 1.3 1 0 0 1 1 1 1 STAT protein, all-alpha domain SH2 PF00017.24 CDJ90803.1 - 8.5e-06 25.8 0.0 2.3e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Tup_N PF08581.10 CDJ90803.1 - 0.00055 20.2 1.9 0.00055 20.2 1.9 2.5 2 1 0 2 2 2 1 Tup N-terminal FlxA PF14282.6 CDJ90803.1 - 0.063 13.3 2.6 0.22 11.5 2.6 1.9 1 0 0 1 1 1 0 FlxA-like protein Endonuclea_NS_2 PF13930.6 CDJ90803.1 - 0.14 12.2 2.9 3.4 7.8 0.1 2.4 2 0 0 2 2 2 0 DNA/RNA non-specific endonuclease TAF6_C PF07571.13 CDJ90804.1 - 7.5e-13 48.6 0.0 2.7e-12 46.9 0.0 2.0 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 CDJ90804.1 - 7.9e-09 35.6 0.2 3.4e-08 33.6 0.0 2.2 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CDJ90804.1 - 0.1 12.9 0.6 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-18kDa PF02269.16 CDJ90804.1 - 0.11 12.6 0.5 0.32 11.1 0.0 2.0 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 CDJ90804.1 - 0.12 12.3 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 Bromodomain associated Eaf7 PF07904.13 CDJ90805.1 - 2.1e-11 44.1 0.0 3.7e-11 43.3 0.0 1.6 1 1 0 1 1 1 1 Chromatin modification-related protein EAF7 zf-U1 PF06220.12 CDJ90806.1 - 8.3e-08 31.9 0.0 1.4e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 U1 zinc finger Cortex-I_coil PF09304.10 CDJ90806.1 - 0.0082 16.3 0.7 0.01 16.1 0.7 1.1 1 0 0 1 1 1 1 Cortexillin I, coiled coil DUF1612 PF07756.12 CDJ90806.1 - 0.01 16.1 0.4 0.011 16.0 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1612) DUF1221 PF06760.11 CDJ90806.1 - 0.022 14.3 0.1 0.024 14.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) zf-C2H2_jaz PF12171.8 CDJ90806.1 - 0.023 15.0 3.5 0.19 12.1 3.5 2.3 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding PH_4 PF15404.6 CDJ90806.1 - 0.031 14.1 0.2 0.033 14.0 0.2 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain T3SS_needle_F PF09392.10 CDJ90806.1 - 0.036 14.3 0.1 0.048 13.8 0.1 1.2 1 0 0 1 1 1 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF zf-DBF PF07535.12 CDJ90806.1 - 0.063 13.4 0.6 0.12 12.6 0.6 1.5 1 1 0 1 1 1 0 DBF zinc finger zf-met PF12874.7 CDJ90806.1 - 0.11 12.9 4.4 3.9 8.0 4.4 2.6 1 1 0 1 1 1 0 Zinc-finger of C2H2 type TMF_TATA_bd PF12325.8 CDJ90807.1 - 0.0033 17.6 0.2 0.0038 17.4 0.2 1.1 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding ABC_tran_CTD PF16326.5 CDJ90807.1 - 0.0096 16.2 2.7 0.015 15.5 2.7 1.4 1 0 0 1 1 1 1 ABC transporter C-terminal domain OmpH PF03938.14 CDJ90807.1 - 0.03 14.7 2.0 0.031 14.6 2.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF5446 PF17522.2 CDJ90807.1 - 0.04 14.1 0.5 0.051 13.8 0.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5446) SKA1 PF07160.12 CDJ90807.1 - 0.056 13.3 0.8 0.064 13.1 0.8 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 CENP-O PF09496.10 CDJ90807.1 - 0.088 12.8 0.1 0.092 12.7 0.1 1.0 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component RabGAP-TBC PF00566.18 CDJ90808.1 - 2.3e-35 122.2 3.2 4.6e-35 121.2 3.2 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 CDJ90808.1 - 3.4e-15 56.1 0.0 5.3e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ90808.1 - 6.9e-10 38.6 0.0 2.3e-09 37.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Rhodanese PF00581.20 CDJ90808.1 - 4.6e-06 27.1 0.1 0.00011 22.7 0.0 2.4 2 0 0 2 2 2 1 Rhodanese-like domain betaPIX_CC PF16523.5 CDJ90809.1 - 4.3e-30 103.4 0.3 1.2e-29 101.9 0.3 1.7 1 0 0 1 1 1 1 betaPIX coiled coil SH3_9 PF14604.6 CDJ90809.1 - 1.8e-15 56.5 0.0 4e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain RhoGEF PF00621.20 CDJ90809.1 - 6.7e-15 55.8 0.0 1.1e-14 55.0 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.28 CDJ90809.1 - 5.7e-14 51.4 0.3 1.5e-13 50.1 0.3 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDJ90809.1 - 4.8e-12 45.4 0.0 1.1e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain RhoGEF67_u2 PF16614.5 CDJ90809.1 - 0.00033 20.7 0.0 0.001 19.1 0.0 1.9 1 0 0 1 1 1 1 Unstructured region two on RhoGEF 6 and 7 CENP-Q PF13094.6 CDJ90809.1 - 0.0056 16.9 0.7 0.021 15.0 0.7 1.9 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit CCDC144C PF14915.6 CDJ90809.1 - 0.031 13.4 0.1 0.074 12.2 0.1 1.6 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Peptidase_S9_N PF02897.15 CDJ90810.1 - 2.4e-83 280.2 0.2 3e-83 279.9 0.2 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Syntaxin PF00804.25 CDJ90811.1 - 6.4e-29 101.1 12.5 9.4e-29 100.5 12.5 1.2 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 CDJ90811.1 - 4.6e-12 45.7 3.2 4.6e-12 45.7 3.2 2.1 1 1 1 2 2 2 1 SNARE domain TBD PF12845.7 CDJ90811.1 - 0.0042 17.0 1.2 0.035 14.0 0.1 2.6 3 0 0 3 3 3 1 TBD domain PCRF PF03462.18 CDJ90811.1 - 0.088 12.7 3.4 1.1 9.0 0.2 2.3 2 0 0 2 2 2 0 PCRF domain BLOC1_2 PF10046.9 CDJ90811.1 - 0.27 11.5 7.3 6.7 7.1 0.3 3.7 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Vps51 PF08700.11 CDJ90811.1 - 0.31 11.2 3.7 32 4.7 0.0 3.3 3 0 0 3 3 3 0 Vps51/Vps67 DUF1664 PF07889.12 CDJ90811.1 - 0.39 10.8 11.6 0.23 11.5 0.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4988 PF16378.5 CDJ90811.1 - 0.41 10.3 9.4 1.2 8.8 1.3 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF2203 PF09969.9 CDJ90811.1 - 0.44 11.3 6.0 7.7 7.3 0.4 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) CENP-F_leu_zip PF10473.9 CDJ90811.1 - 0.57 10.2 11.9 1.3 9.0 2.0 2.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MMPL PF03176.15 CDJ90811.1 - 0.65 8.9 6.3 0.82 8.5 6.3 1.4 1 1 0 1 1 1 0 MMPL family DASH_Dam1 PF08653.10 CDJ90811.1 - 0.82 9.5 5.6 30 4.5 0.2 3.9 3 1 1 4 4 4 0 DASH complex subunit Dam1 Sec34 PF04136.15 CDJ90811.1 - 0.83 9.5 4.6 3.9 7.4 0.2 3.1 2 1 1 3 3 3 0 Sec34-like family DUF4709 PF15821.5 CDJ90811.1 - 0.97 9.7 5.9 1.7 8.9 0.7 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4709) GAS PF13851.6 CDJ90811.1 - 1.1 8.6 8.1 7.2 5.9 2.1 2.6 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 CDJ90811.1 - 1.3 8.1 6.2 6.5 5.7 3.0 2.2 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tup_N PF08581.10 CDJ90811.1 - 1.4 9.3 9.9 13 6.1 0.4 3.5 2 1 1 3 3 3 0 Tup N-terminal SOAR PF16533.5 CDJ90811.1 - 1.5 8.9 10.5 0.16 12.0 1.0 3.2 2 2 1 3 3 3 0 STIM1 Orai1-activating region DUF4515 PF14988.6 CDJ90811.1 - 1.8 8.3 9.2 0.21 11.4 0.6 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4515) Fez1 PF06818.15 CDJ90811.1 - 2.3 8.6 11.3 3.3 8.1 4.3 2.5 1 1 1 2 2 2 0 Fez1 CK2S PF15011.6 CDJ90811.1 - 3.1 7.7 6.1 23 4.8 0.2 3.2 2 1 1 3 3 3 0 Casein Kinase 2 substrate Na_K-ATPase PF00287.18 CDJ90812.1 - 6.5e-73 245.4 0.1 7.4e-73 245.2 0.1 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain DUF2417 PF10329.9 CDJ90812.1 - 0.033 13.6 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Region of unknown function (DUF2417) TFA2_Winged_2 PF18121.1 CDJ90813.1 - 0.00056 19.5 9.1 1.7 8.4 0.9 5.0 4 0 0 4 4 4 3 TFA2 Winged helix domain 2 CENP-F_leu_zip PF10473.9 CDJ90813.1 - 0.007 16.4 12.6 0.007 16.4 12.6 5.5 1 1 4 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 CDJ90813.1 - 0.15 11.4 84.7 0.11 11.8 25.6 5.8 2 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding Golgin_A5 PF09787.9 CDJ90813.1 - 3.8 6.9 77.4 0.45 9.9 10.2 3.7 1 1 2 3 3 3 0 Golgin subfamily A member 5 Hist_deacetyl PF00850.19 CDJ90815.1 - 3.7e-84 282.8 0.3 9.3e-83 278.2 0.0 2.2 2 0 0 2 2 2 2 Histone deacetylase domain Pol_alpha_B_N PF08418.10 CDJ90815.1 - 1.6 8.6 14.2 0.42 10.5 10.7 1.7 1 1 1 2 2 2 0 DNA polymerase alpha subunit B N-terminal UDPGT PF00201.18 CDJ90818.1 - 3.9e-52 177.7 0.0 4.4e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ90818.1 - 2e-07 31.1 0.0 3.8e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.6 CDJ90818.1 - 0.083 12.9 0.1 4.8 7.1 0.1 2.8 2 1 0 2 2 2 0 Glycosyltransferase Family 4 ABC1 PF03109.16 CDJ90819.1 - 1.3e-17 64.1 0.0 4e-17 62.5 0.0 1.9 1 0 0 1 1 1 1 ABC1 family Flavodoxin_1 PF00258.25 CDJ90819.1 - 0.00047 20.4 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin APH PF01636.23 CDJ90819.1 - 0.0027 17.7 0.0 0.0066 16.4 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family GNAT_C PF18164.1 CDJ90819.1 - 0.028 14.1 0.3 0.13 12.0 0.0 2.1 1 1 1 2 2 2 0 GNAT-like C-terminal domain RIO1 PF01163.22 CDJ90819.1 - 0.082 12.5 0.3 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 RIO1 family EMC3_TMCO1 PF01956.16 CDJ90820.1 - 0.52 10.0 1.4 0.91 9.2 1.4 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like LisH PF08513.11 CDJ90821.1 - 7.9e-06 25.6 0.4 2.1e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 LisH WD40_like PF17005.5 CDJ90821.1 - 0.0028 17.0 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 WD40-like domain PQQ PF01011.21 CDJ90821.1 - 0.0052 16.7 0.0 1.6 8.8 0.0 3.0 3 0 0 3 3 3 1 PQQ enzyme repeat WD40 PF00400.32 CDJ90821.1 - 0.091 13.7 0.4 1.3 10.0 0.2 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ90821.1 - 0.14 12.5 0.0 0.9 9.9 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Nop14 PF04147.12 CDJ90821.1 - 5.5 5.1 21.3 7.9 4.5 21.3 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 CDJ90821.1 - 7.2 5.8 23.3 11 5.3 23.3 1.2 1 0 0 1 1 1 0 BUD22 Bestrophin PF01062.21 CDJ90822.1 - 2.1e-66 224.3 1.4 2.7e-66 223.9 1.4 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Trypsin PF00089.26 CDJ90823.1 - 4.8e-44 150.8 0.0 5.6e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CDJ90823.1 - 1.8e-06 28.9 0.0 3.4e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain CoA_binding_3 PF13727.6 CDJ90824.1 - 0.12 12.3 0.1 0.14 12.2 0.1 1.1 1 0 0 1 1 1 0 CoA-binding domain Thioredoxin_6 PF13848.6 CDJ90825.1 - 1.7e-10 41.1 2.6 3.3e-06 27.1 0.2 2.5 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 CDJ90825.1 - 0.00028 20.8 0.1 0.014 15.4 0.1 3.0 3 0 0 3 3 3 1 Thioredoxin NIR_SIR_ferr PF03460.17 CDJ90825.1 - 0.049 13.5 0.0 0.18 11.7 0.0 1.9 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain Pro_CA PF00484.19 CDJ90826.1 - 1.4e-36 126.1 0.0 2e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase HlyIII PF03006.20 CDJ90827.1 - 0.026 14.2 0.2 0.029 14.1 0.2 1.1 1 0 0 1 1 1 0 Haemolysin-III related Oxysterol_BP PF01237.18 CDJ90828.1 - 1.5e-85 287.3 0.0 2.4e-85 286.6 0.0 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 CDJ90828.1 - 2.9e-12 47.0 0.2 6.3e-12 45.9 0.2 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CDJ90828.1 - 1.7e-11 44.2 0.3 3.1e-11 43.4 0.3 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 CDJ90828.1 - 4.2e-05 23.9 1.6 0.0014 19.1 1.6 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain DUF5519 PF17648.1 CDJ90828.1 - 0.053 13.4 0.2 0.13 12.1 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5519) PH_6 PF15406.6 CDJ90828.1 - 0.067 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain TB2_DP1_HVA22 PF03134.19 CDJ90829.1 - 3e-28 97.6 6.9 5.4e-28 96.7 6.9 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family CH PF00307.31 CDJ90830.1 - 5.3e-15 55.5 0.9 2.9e-12 46.7 0.2 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CDJ90830.1 - 0.0062 16.3 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 CAMSAP CH domain HAUS5 PF14817.6 CDJ90830.1 - 0.073 11.8 0.1 0.073 11.8 0.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Spectrin PF00435.21 CDJ90831.1 - 4.6e-15 56.0 121.4 1.2e-08 35.4 4.1 17.4 14 6 3 18 18 18 8 Spectrin repeat DZR PF12773.7 CDJ90832.1 - 3.2e-08 33.5 36.9 1.3e-05 25.1 15.2 1.7 1 1 2 3 3 3 3 Double zinc ribbon zf-ribbon_3 PF13248.6 CDJ90832.1 - 2.3e-06 26.8 13.6 0.0011 18.3 4.3 2.5 2 1 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_2 PF13240.6 CDJ90832.1 - 4.7e-05 23.0 11.8 0.0024 17.5 0.6 2.4 2 1 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_15 PF17032.5 CDJ90832.1 - 0.00015 22.4 5.6 0.014 16.1 1.0 2.1 2 0 0 2 2 2 2 zinc-ribbon family Rhodanese_C PF12368.8 CDJ90832.1 - 0.079 13.3 8.3 0.13 12.6 8.3 1.3 1 0 0 1 1 1 0 Rhodanase C-terminal DUF2321 PF10083.9 CDJ90832.1 - 0.36 10.4 7.1 0.27 10.8 2.4 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-C3HC4_3 PF13920.6 CDJ90832.1 - 0.54 10.2 14.7 0.82 9.6 14.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cript PF10235.9 CDJ90832.1 - 0.58 10.8 9.4 2.1 8.9 0.7 2.1 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT NOB1_Zn_bind PF08772.11 CDJ90832.1 - 0.97 9.6 12.3 6.6 7.0 4.2 2.1 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like FdhE PF04216.12 CDJ90832.1 - 1.4 8.7 6.6 1.7 8.4 6.6 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf-RING_10 PF16685.5 CDJ90832.1 - 7.9 6.7 14.1 13 6.0 14.1 1.4 1 1 0 1 1 1 0 zinc RING finger of MSL2 HAP1_N PF04849.13 CDJ90833.1 - 5e-33 114.6 31.8 1.3e-31 110.0 31.8 2.2 1 1 0 1 1 1 1 HAP1 N-terminal conserved region Milton PF12448.8 CDJ90833.1 - 0.0018 18.4 0.1 0.0018 18.4 0.1 2.6 2 1 0 2 2 2 1 Kinesin associated protein CxxCxxCC PF03692.15 CDJ90833.1 - 0.12 13.1 0.8 0.44 11.3 0.8 1.9 1 0 0 1 1 1 0 Putative zinc- or iron-chelating domain CCDC144C PF14915.6 CDJ90833.1 - 0.18 10.9 24.7 0.02 14.0 16.5 2.2 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region BPL_N PF09825.9 CDJ90833.1 - 0.43 9.6 6.7 0.71 8.9 6.7 1.4 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF3824 PF12868.7 CDJ90834.1 - 0.12 13.1 3.3 0.23 12.1 3.3 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Astacin PF01400.24 CDJ90836.1 - 7.7e-26 90.9 8.7 1.7e-13 50.6 2.4 2.6 2 1 1 3 3 3 2 Astacin (Peptidase family M12A) RVT_1 PF00078.27 CDJ90838.1 - 1.8e-25 89.8 0.0 3e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ShK PF01549.24 CDJ90839.1 - 0.00011 22.6 2.8 0.00016 22.1 2.8 1.3 1 0 0 1 1 1 1 ShK domain-like Collagen PF01391.18 CDJ90840.1 - 5.7e-26 90.1 106.1 1.8e-10 40.4 33.1 4.2 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ90840.1 - 1.5e-17 63.4 0.2 1.9e-17 63.1 0.2 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain COX14 PF14880.6 CDJ90840.1 - 0.013 15.3 0.8 0.02 14.7 0.8 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c assembly SCVP PF17619.2 CDJ90841.1 - 3.1e-46 156.2 4.7 3.1e-24 85.7 1.5 2.3 2 0 0 2 2 2 2 Secreted clade V proteins DUF866 PF05907.13 CDJ90841.1 - 0.056 13.4 0.2 0.6 10.0 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF866) SCVP PF17619.2 CDJ90842.1 - 7.4e-26 90.9 0.4 9.9e-26 90.4 0.4 1.2 1 0 0 1 1 1 1 Secreted clade V proteins SCVP PF17619.2 CDJ90843.1 - 4.2e-11 43.5 0.0 6.4e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Secreted clade V proteins SCVP PF17619.2 CDJ90844.1 - 2e-16 60.6 0.0 2.8e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Secreted clade V proteins ING PF12998.7 CDJ90846.1 - 2.8e-15 56.8 6.7 4.6e-15 56.0 6.7 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CDJ90846.1 - 1.3e-06 28.2 9.4 2.7e-06 27.2 9.4 1.5 1 0 0 1 1 1 1 PHD-finger SPX PF03105.19 CDJ90846.1 - 0.002 18.2 0.7 0.0025 17.8 0.7 1.1 1 0 0 1 1 1 1 SPX domain PHD_2 PF13831.6 CDJ90846.1 - 0.008 15.7 2.8 0.018 14.6 2.8 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CDJ90846.1 - 0.021 15.1 1.7 0.067 13.5 1.7 2.0 1 0 0 1 1 1 0 PHD-like zinc-binding domain Osmo_CC PF08946.10 CDJ90846.1 - 1.8 8.9 8.6 0.32 11.3 2.9 2.5 2 1 1 3 3 3 0 Osmosensory transporter coiled coil Ribosomal_S30AE PF02482.19 CDJ90846.1 - 7.7 7.4 9.9 5.4 7.9 7.9 1.8 2 1 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein Methyltransf_16 PF10294.9 CDJ90847.1 - 6e-37 127.0 0.1 7.1e-37 126.8 0.1 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 CDJ90847.1 - 0.002 18.0 0.0 0.0041 17.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ90847.1 - 0.015 14.8 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 CDJ90847.1 - 0.027 15.2 0.0 0.046 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 CDJ90847.1 - 0.054 12.8 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G PrmA PF06325.13 CDJ90847.1 - 0.075 12.4 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) SAM_MT PF04445.13 CDJ90847.1 - 0.21 11.0 0.0 0.29 10.5 0.0 1.1 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Peptidase_M1 PF01433.20 CDJ90848.1 - 1.3e-47 162.2 0.0 1.8e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 CDJ90848.1 - 1.9e-28 98.8 0.0 3.7e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 CDJ90848.1 - 4.6e-26 92.2 0.0 7.1e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 CDJ90848.1 - 0.12 12.1 0.0 0.53 9.9 0.0 1.9 2 0 0 2 2 2 0 Peptidase MA superfamily Peptidase_M48 PF01435.18 CDJ90848.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M48 Peptidase_M1 PF01433.20 CDJ90849.1 - 1.4e-46 158.8 0.1 1.9e-46 158.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CDJ90849.1 - 1e-23 84.5 0.0 1.6e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Ribonuclease_T2 PF00445.18 CDJ90849.1 - 0.027 14.7 0.2 0.077 13.2 0.2 1.9 1 1 0 1 1 1 0 Ribonuclease T2 family Peptidase_M48 PF01435.18 CDJ90849.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M48 Peptidase_MA_2 PF13485.6 CDJ90849.1 - 0.097 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase MA superfamily PALP PF00291.25 CDJ90850.1 - 0.00013 21.5 0.1 0.00022 20.7 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.25 CDJ90850.1 - 0.00088 19.0 0.1 0.0018 18.0 0.1 1.6 1 0 0 1 1 1 1 ACT domain PALP PF00291.25 CDJ90851.1 - 9.3e-25 87.6 0.0 1.1e-24 87.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GRDA PF04723.14 CDJ90851.1 - 0.11 12.2 0.0 0.66 9.7 0.0 1.9 2 0 0 2 2 2 0 Glycine reductase complex selenoprotein A DUF4337 PF14235.6 CDJ90852.1 - 0.32 11.1 2.0 0.56 10.3 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) MscS_TM PF12794.7 CDJ90852.1 - 0.71 8.7 5.0 1 8.1 5.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DivIC PF04977.15 CDJ90852.1 - 1.9 8.3 7.9 5.1 6.9 7.9 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF4140 PF13600.6 CDJ90852.1 - 4 7.9 5.8 1.7 9.2 2.2 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Kinesin PF00225.23 CDJ90854.1 - 1.1e-19 70.6 0.0 3.7e-19 68.8 0.0 1.7 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ90854.1 - 9.4e-06 25.6 0.0 1.7e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding OxoGdeHyase_C PF16870.5 CDJ90855.1 - 1.1e-44 151.9 0.0 1.2e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal PFOR_II PF17147.4 CDJ90855.1 - 0.054 13.8 0.0 0.089 13.1 0.0 1.4 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II E1_dh PF00676.20 CDJ90856.1 - 4.5e-46 157.2 0.0 6e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 CDJ90856.1 - 7.7e-06 25.7 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain RRM_1 PF00076.22 CDJ90857.1 - 1.8e-10 40.5 0.2 2.9e-10 39.8 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 CDJ90857.1 - 0.0016 18.4 0.1 0.0036 17.3 0.1 1.6 1 0 0 1 1 1 1 DbpA RNA binding domain DcrB PF08786.11 CDJ90857.1 - 0.09 12.9 12.8 0.18 11.9 12.3 1.8 1 1 0 1 1 1 0 DcrB Dpy-30 PF05186.13 CDJ90858.1 - 3.5e-18 65.0 0.1 5e-18 64.5 0.1 1.2 1 0 0 1 1 1 1 Dpy-30 motif Zona_pellucida PF00100.23 CDJ90859.1 - 1.2e-11 44.9 0.1 1.5e-11 44.6 0.1 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain ChitinaseA_N PF08329.10 CDJ90859.1 - 0.25 11.0 0.1 0.25 11.0 0.1 1.5 2 0 0 2 2 2 0 Chitinase A, N-terminal domain Ank_2 PF12796.7 CDJ90860.1 - 4.5e-40 136.1 2.8 8.3e-13 48.7 0.0 5.0 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ90860.1 - 2.4e-34 117.3 6.1 6.6e-08 33.0 0.2 8.1 5 3 3 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 CDJ90860.1 - 2.9e-31 106.5 18.5 7.5e-05 23.0 0.0 9.8 10 0 0 10 10 10 6 Ankyrin repeat Ank_3 PF13606.6 CDJ90860.1 - 5.1e-30 100.2 12.3 3.3e-05 23.9 0.0 9.5 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 CDJ90860.1 - 2.4e-27 94.6 4.9 1.6e-05 25.1 0.0 6.9 4 3 2 6 6 6 6 Ankyrin repeats (many copies) SOCS_box PF07525.16 CDJ90860.1 - 1.5e-11 44.4 3.2 7.2e-09 35.9 1.2 2.7 2 0 0 2 2 2 2 SOCS box Malectin PF11721.8 CDJ90861.1 - 4.2e-34 118.0 0.3 5.5e-34 117.6 0.3 1.1 1 0 0 1 1 1 1 Malectin domain DUF2890 PF11081.8 CDJ90861.1 - 0.37 10.9 1.9 0.59 10.2 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) zf-C4 PF00105.18 CDJ90862.1 - 1.8e-06 28.3 6.6 3.3e-06 27.4 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) MFS_2 PF13347.6 CDJ90863.1 - 3e-25 88.6 26.9 3.9e-25 88.3 26.9 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 CDJ90863.1 - 2.1e-12 46.7 31.6 1.6e-11 43.7 31.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4350 PF14258.6 CDJ90863.1 - 0.066 13.7 0.1 11 6.6 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4350) PI_PP_I PF18363.1 CDJ90863.1 - 0.13 12.5 0.2 3.4 7.9 0.0 3.2 3 1 0 3 3 3 0 Phosphoinositide phosphatase insertion domain MOSC PF03473.17 CDJ90864.1 - 3.9e-28 98.1 0.0 7.2e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 CDJ90864.1 - 1.4e-27 96.0 0.0 2e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain F-box PF00646.33 CDJ90865.1 - 1.9e-05 24.4 0.2 1.9e-05 24.4 0.2 2.8 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 CDJ90865.1 - 0.00056 19.8 0.8 0.0029 17.5 0.1 2.3 2 0 0 2 2 2 1 F-box-like MOSC PF03473.17 CDJ90866.1 - 2.2e-51 173.3 0.0 2e-25 89.3 0.0 2.4 2 0 0 2 2 2 2 MOSC domain MOSC_N PF03476.16 CDJ90866.1 - 4.2e-23 81.5 0.0 8.1e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain DEAD PF00270.29 CDJ90866.1 - 0.0064 16.3 0.0 3.1 7.5 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Phage_portal PF04860.12 CDJ90866.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein Glyco_transf_10 PF00852.19 CDJ90867.1 - 2.2e-47 161.1 1.5 2.8e-47 160.7 1.5 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CDJ90867.1 - 3.8e-11 43.4 1.8 7.5e-11 42.5 0.2 2.2 3 0 0 3 3 3 1 Fucosyltransferase, N-terminal 7TM_GPCR_Srt PF10321.9 CDJ90868.1 - 1.8e-06 27.2 15.4 2.2e-06 26.9 15.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt 7TM_GPCR_Srx PF10328.9 CDJ90868.1 - 1.8e-05 24.5 19.9 2.6e-05 24.0 19.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Tn7_TnsC_Int PF11426.8 CDJ90869.1 - 0.03 14.5 0.1 0.12 12.6 0.1 2.0 1 0 0 1 1 1 0 Tn7 transposition regulator TnsC DUF4472 PF14739.6 CDJ90869.1 - 0.66 10.7 19.0 2.2 9.1 8.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) DUF724 PF05266.14 CDJ90869.1 - 1.3 8.8 18.9 1 9.2 9.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) FliD_N PF02465.18 CDJ90869.1 - 4.9 7.9 10.9 0.24 12.1 0.7 2.9 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Laminin_II PF06009.12 CDJ90869.1 - 8.2 6.4 12.3 8.8 6.3 6.5 2.5 1 1 0 2 2 2 0 Laminin Domain II YabA PF06156.13 CDJ90869.1 - 9.2 7.0 20.9 0.15 12.7 6.9 2.7 1 1 2 3 3 3 0 Initiation control protein YabA TTR-52 PF01060.23 CDJ90870.1 - 7e-38 129.2 0.0 6.5e-27 94.0 0.0 2.3 2 0 0 2 2 2 2 Transthyretin-like family DUF4198 PF10670.9 CDJ90870.1 - 0.095 13.1 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) CarboxypepD_reg PF13620.6 CDJ90870.1 - 0.13 12.6 0.0 0.92 9.8 0.0 2.1 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain G-alpha PF00503.20 CDJ90871.1 - 9.2e-117 390.1 2.7 1.1e-116 389.9 2.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDJ90871.1 - 6.5e-16 58.3 3.4 1.1e-11 44.5 1.3 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 CDJ90871.1 - 7e-05 23.0 0.2 0.072 13.3 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CDJ90871.1 - 0.0018 17.7 4.9 0.01 15.2 2.4 2.6 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 CDJ90871.1 - 0.0054 16.8 0.0 0.019 15.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain Ras PF00071.22 CDJ90871.1 - 0.0092 15.6 2.0 2 8.0 1.0 2.5 2 1 0 2 2 2 2 Ras family AAA_24 PF13479.6 CDJ90871.1 - 0.047 13.4 0.0 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CDJ90871.1 - 0.058 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain TniB PF05621.11 CDJ90871.1 - 0.079 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Calx-beta PF03160.14 CDJ90872.1 - 8.3e-58 192.8 5.9 4e-30 103.9 0.7 2.8 3 0 0 3 3 3 2 Calx-beta domain Na_Ca_ex_C PF16494.5 CDJ90872.1 - 9.2e-30 103.7 1.3 9.2e-30 103.7 1.3 1.7 2 0 0 2 2 2 1 C-terminal extension of sodium/calcium exchanger domain Na_Ca_ex PF01699.24 CDJ90872.1 - 5.3e-24 84.9 7.7 8.8e-24 84.2 7.7 1.3 1 0 0 1 1 1 1 Sodium/calcium exchanger protein PAW PF04721.17 CDJ90873.1 - 5.3e-48 163.4 0.1 7.2e-48 163.0 0.1 1.2 1 0 0 1 1 1 1 PNGase C-terminal domain, mannose-binding module PAW Thioredoxin PF00085.20 CDJ90873.1 - 5.2e-25 87.4 0.0 9.9e-25 86.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Transglut_core PF01841.19 CDJ90873.1 - 1.2e-09 38.7 0.0 2.5e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 CDJ90873.1 - 1.6e-09 37.6 0.2 2.9e-09 36.7 0.2 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Thioredoxin_8 PF13905.6 CDJ90873.1 - 9.2e-05 22.7 0.0 0.0049 17.2 0.0 2.5 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 CDJ90873.1 - 0.00011 22.0 0.0 0.00049 19.9 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 CDJ90873.1 - 0.00014 22.3 0.1 0.00067 20.1 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 CDJ90873.1 - 0.00089 19.1 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 CDJ90873.1 - 0.02 14.6 0.0 3.4 7.4 0.0 2.4 1 1 1 2 2 2 0 Redoxin TrbC_Ftype PF09673.10 CDJ90873.1 - 0.033 14.2 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein OST3_OST6 PF04756.13 CDJ90873.1 - 0.045 13.1 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF974 PF06159.13 CDJ90874.1 - 7.9e-68 228.9 0.0 1e-67 228.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) NAC PF01849.18 CDJ90875.1 - 4.6e-23 80.9 0.5 9.6e-23 79.9 0.5 1.6 1 0 0 1 1 1 1 NAC domain IMS_HHH PF11798.8 CDJ90875.1 - 0.093 13.1 0.2 0.51 10.8 0.0 2.4 3 0 0 3 3 3 0 IMS family HHH motif Snf7 PF03357.21 CDJ90876.1 - 9.6e-49 165.3 13.1 1.2e-48 165.0 13.1 1.1 1 0 0 1 1 1 1 Snf7 Ribosomal_L22 PF00237.19 CDJ90876.1 - 0.45 10.8 3.2 3.1 8.1 0.1 2.9 1 1 0 2 2 2 0 Ribosomal protein L22p/L17e EF-hand_7 PF13499.6 CDJ90877.1 - 2.7e-25 88.6 9.0 9.4e-10 38.8 0.2 3.9 3 2 1 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 CDJ90877.1 - 3.4e-25 85.6 13.0 0.0016 17.9 0.1 6.7 6 0 0 6 6 6 6 EF hand EF-hand_6 PF13405.6 CDJ90877.1 - 1.1e-21 74.8 4.5 0.0063 16.4 0.0 6.5 6 0 0 6 6 6 6 EF-hand domain EF-hand_5 PF13202.6 CDJ90877.1 - 3.1e-21 73.8 17.1 0.00013 21.3 0.0 6.8 7 0 0 7 7 7 5 EF hand EF-hand_8 PF13833.6 CDJ90877.1 - 5.7e-12 45.3 6.6 0.048 13.5 0.0 5.7 6 0 0 6 6 6 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ90877.1 - 6.6e-11 42.5 3.8 7.5e-05 23.0 0.1 3.6 3 1 1 4 4 4 3 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 CDJ90877.1 - 0.018 15.2 10.9 2.1 8.6 0.0 5.1 4 2 2 6 6 6 0 Dockerin type I domain EF-hand_10 PF14788.6 CDJ90877.1 - 0.076 12.9 0.2 11 5.9 0.1 3.1 3 0 0 3 3 3 0 EF hand EF-hand_4 PF12763.7 CDJ90877.1 - 1.9 8.5 6.5 36 4.4 0.0 4.1 4 1 0 4 4 4 0 Cytoskeletal-regulatory complex EF hand FG-GAP PF01839.23 CDJ90877.1 - 5.7 7.2 12.4 26 5.0 0.4 4.1 4 0 0 4 4 4 0 FG-GAP repeat TPR_2 PF07719.17 CDJ90878.1 - 2.6e-10 39.6 6.0 0.0013 18.7 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ90878.1 - 6.3e-07 28.9 4.5 0.0092 15.8 0.1 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ90878.1 - 6.9e-07 29.7 6.2 4.8e-05 23.8 0.6 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ90878.1 - 4.7e-06 26.2 3.1 0.0083 15.8 0.3 3.5 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.6 CDJ90878.1 - 1.8e-05 25.1 0.2 0.046 14.6 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ90878.1 - 4.2e-05 23.4 2.5 0.017 15.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 CDJ90878.1 - 0.00076 19.9 2.6 0.0013 19.2 2.6 1.5 1 0 0 1 1 1 1 Bacterial transcriptional activator domain TPR_12 PF13424.6 CDJ90878.1 - 0.0011 19.2 2.1 0.99 9.7 0.1 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ90878.1 - 0.0012 19.0 1.3 0.082 13.1 0.6 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CDJ90878.1 - 0.0052 17.4 0.9 4.9 7.9 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ90878.1 - 0.0069 16.7 1.0 4.5 7.9 0.2 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 CDJ90878.1 - 0.027 14.5 0.8 0.068 13.2 0.1 2.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 CDJ90878.1 - 0.038 14.6 1.1 6 7.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat CDV3 PF15359.6 CDJ90878.1 - 0.057 13.9 0.3 0.09 13.3 0.3 1.3 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 TPR_7 PF13176.6 CDJ90878.1 - 0.062 13.3 0.1 20 5.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat 7tm_1 PF00001.21 CDJ90879.1 - 2e-52 178.1 2.0 2.4e-52 177.8 2.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ90879.1 - 7.2e-11 41.9 4.9 9.8e-11 41.5 4.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 CDJ90879.1 - 2.9e-06 27.1 10.2 1.2e-05 25.1 10.2 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 CDJ90879.1 - 7.9e-05 22.2 6.0 0.00014 21.3 6.0 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.9 CDJ90879.1 - 0.00075 18.9 11.6 0.023 14.0 4.4 2.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 CDJ90879.1 - 0.00087 19.1 11.3 0.0013 18.6 4.9 2.0 1 1 1 2 2 2 1 Olfactory receptor CcmH PF03918.14 CDJ90879.1 - 0.014 14.7 0.4 2.4 7.4 0.2 2.4 2 0 0 2 2 2 0 Cytochrome C biogenesis protein DUF3377 PF11857.8 CDJ90879.1 - 0.04 13.9 0.1 0.04 13.9 0.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF3377) TMEM154 PF15102.6 CDJ90879.1 - 0.24 11.3 0.7 9 6.2 0.0 2.5 2 0 0 2 2 2 0 TMEM154 protein family DUF4491 PF14898.6 CDJ90879.1 - 4.2 7.9 7.6 1.1 9.8 0.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4491) Phage_Gp23 PF10669.9 CDJ90880.1 - 0.0043 17.4 0.0 0.006 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein gp23 (Bacteriophage A118) PigN PF04987.14 CDJ90880.1 - 0.022 13.7 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) AgrB PF04647.15 CDJ90880.1 - 0.041 13.2 0.2 0.057 12.7 0.2 1.1 1 0 0 1 1 1 0 Accessory gene regulator B Conotoxin PF02950.17 CDJ90880.1 - 0.061 14.3 0.0 0.1 13.6 0.0 1.3 1 0 0 1 1 1 0 Conotoxin DUF4834 PF16118.5 CDJ90880.1 - 0.063 14.3 0.0 0.11 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Ac76 PF05814.11 CDJ90880.1 - 0.14 12.2 0.6 0.25 11.4 0.6 1.4 1 0 0 1 1 1 0 Orf76 (Ac76) EphA2_TM PF14575.6 CDJ90880.1 - 0.19 12.7 0.0 0.38 11.7 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2663 PF10864.8 CDJ90880.1 - 0.36 11.2 0.0 0.36 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) PIRT PF15099.6 CDJ90880.1 - 0.73 9.4 4.2 2.2 7.9 4.2 1.8 1 1 0 1 1 1 0 Phosphoinositide-interacting protein family OAD_gamma PF04277.13 CDJ90880.1 - 2.5 8.8 7.5 9.6 6.9 7.5 1.8 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Motile_Sperm PF00635.26 CDJ90881.1 - 6.7e-20 71.0 0.0 8.5e-20 70.6 0.0 1.1 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Clathrin PF00637.20 CDJ90883.1 - 2.2e-24 86.0 4.1 1.6e-22 79.9 0.9 2.5 3 0 0 3 3 3 2 Region in Clathrin and VPS Vps39_1 PF10366.9 CDJ90883.1 - 2.9e-05 24.3 5.4 0.00033 20.9 0.5 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 CDJ90883.1 - 0.0005 20.5 0.1 0.0005 20.5 0.1 2.6 3 1 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 PGBA_N PF15436.6 CDJ90883.1 - 0.025 14.2 0.1 0.036 13.7 0.1 1.2 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA N-terminal Nucleolin_bd PF16725.5 CDJ90883.1 - 0.027 14.1 0.4 0.86 9.3 0.2 2.5 2 0 0 2 2 2 0 Nucleolin binding domain TPR_8 PF13181.6 CDJ90883.1 - 0.035 14.3 1.1 0.21 11.9 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ90883.1 - 0.037 14.1 5.0 0.068 13.2 0.1 3.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ90883.1 - 0.061 13.2 2.8 14 5.7 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ90883.1 - 0.087 13.7 1.5 5.6 8.1 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat YkuI_C PF10388.9 CDJ90883.1 - 0.088 12.6 1.0 4.2 7.1 0.1 2.2 1 1 1 2 2 2 0 EAL-domain associated signalling protein domain Exo_endo_phos_2 PF14529.6 CDJ90884.1 - 2.3e-08 33.9 0.0 4.6e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase APP_E2 PF12925.7 CDJ90884.1 - 0.14 11.8 0.2 0.21 11.3 0.2 1.2 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein RVT_1 PF00078.27 CDJ90886.1 - 3.7e-15 56.1 0.1 1.2e-14 54.4 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CDJ90886.1 - 0.006 16.1 0.0 0.0098 15.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 CDJ90887.1 - 3.7e-52 177.0 0.0 5.7e-39 133.9 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) CagE_TrbE_VirB PF03135.14 CDJ90887.1 - 0.0026 17.9 0.7 2.2 8.3 0.0 2.6 2 1 0 2 2 2 2 CagE, TrbE, VirB family, component of type IV transporter system DUF5499 PF17603.2 CDJ90887.1 - 0.008 16.8 1.2 4 8.1 0.0 3.0 3 0 0 3 3 3 2 Family of unknown function (DUF5499) Peptidase_S66 PF02016.15 CDJ90887.1 - 0.017 15.3 0.1 6.4 6.9 0.0 2.5 2 0 0 2 2 2 0 LD-carboxypeptidase N-terminal domain Phage_sheath_1 PF04984.14 CDJ90887.1 - 0.06 13.2 0.2 17 5.2 0.0 3.1 4 0 0 4 4 4 0 Phage tail sheath protein subtilisin-like domain DUF2703 PF10865.8 CDJ90887.1 - 0.088 13.0 0.8 20 5.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) OmpH PF03938.14 CDJ90887.1 - 0.25 11.6 3.6 10 6.5 0.5 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FtsX_ECD PF18075.1 CDJ90887.1 - 0.27 11.9 1.4 24 5.6 0.1 2.8 2 0 0 2 2 2 0 FtsX extracellular domain MAD PF05557.13 CDJ90887.1 - 0.28 9.5 2.6 7.1 4.9 0.2 2.1 2 0 0 2 2 2 0 Mitotic checkpoint protein YkyA PF10368.9 CDJ90887.1 - 3.5 7.3 7.6 13 5.4 0.6 2.3 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein RVT_1 PF00078.27 CDJ90891.1 - 3.1e-24 85.7 0.0 4e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CLP1_N PF16573.5 CDJ90891.1 - 0.17 12.1 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 N-terminal beta-sandwich domain of polyadenylation factor RVT_1 PF00078.27 CDJ90892.1 - 1.4e-09 37.8 0.0 1.9e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) C2 PF00168.30 CDJ90893.1 - 1.2e-11 44.8 0.1 3.5e-07 30.4 0.1 2.4 2 0 0 2 2 2 2 C2 domain DUF2258 PF10015.9 CDJ90893.1 - 0.13 12.4 0.0 0.83 9.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) Prominin PF05478.11 CDJ90894.1 - 0.047 11.7 0.0 0.047 11.7 0.0 1.0 1 0 0 1 1 1 0 Prominin Baculo_11_kDa PF06143.11 CDJ90894.1 - 0.054 13.1 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family TMEM154 PF15102.6 CDJ90894.1 - 0.06 13.2 0.0 0.065 13.1 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family DUF2116 PF09889.9 CDJ90894.1 - 0.068 13.2 0.9 0.095 12.7 0.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF5305 PF17231.2 CDJ90894.1 - 0.1 12.0 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) GAPT PF11770.8 CDJ90894.1 - 1.3 8.8 2.9 0.94 9.3 1.5 1.5 1 1 1 2 2 2 0 GRB2-binding adapter (GAPT) Med14 PF08638.11 CDJ90895.1 - 3.5e-50 170.1 0.3 7.4e-50 169.0 0.3 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 DDT PF02791.17 CDJ90895.1 - 0.1 12.9 0.0 0.52 10.7 0.0 2.1 2 0 0 2 2 2 0 DDT domain TFIIE_beta PF02186.15 CDJ90897.1 - 2.4e-18 66.1 0.0 4.7e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 TFIIE beta subunit core domain MecA_N PF05223.11 CDJ90897.1 - 0.0034 17.6 0.2 0.0069 16.6 0.0 1.6 2 0 0 2 2 2 1 NTF2-like N-terminal transpeptidase domain TFA2_Winged_2 PF18121.1 CDJ90897.1 - 0.0079 15.9 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 PAXIP1_C PF15364.6 CDJ90897.1 - 0.016 15.5 0.5 0.024 14.9 0.5 1.3 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Cation_efflux PF01545.21 CDJ90898.1 - 1.8e-26 93.1 12.4 2.7e-26 92.5 12.4 1.3 1 0 0 1 1 1 1 Cation efflux family HIG_1_N PF04588.13 CDJ90901.1 - 2.3e-14 53.3 1.7 3.6e-14 52.7 1.7 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF883 PF05957.13 CDJ90901.1 - 0.0096 16.5 0.0 0.016 15.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) RNA_pol_Rpb5_C PF01191.19 CDJ90902.1 - 1.1e-34 118.1 0.2 1.8e-34 117.4 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 CDJ90902.1 - 3.4e-19 69.2 2.8 6.1e-10 39.5 0.1 2.4 1 1 1 2 2 2 2 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 CDJ90902.1 - 0.033 14.2 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease Microcin PF03526.13 CDJ90902.1 - 0.095 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Colicin E1 (microcin) immunity protein BTB_2 PF02214.22 CDJ90903.1 - 5.4e-22 77.9 0.0 1.8e-21 76.3 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 CDJ90903.1 - 0.07 13.2 0.0 0.47 10.6 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain SCP2 PF02036.17 CDJ90904.1 - 5e-22 78.3 0.4 6.2e-22 78.0 0.4 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 CDJ90904.1 - 3.2e-06 27.4 0.2 4e-06 27.1 0.2 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 CDJ90904.1 - 0.0072 16.7 0.0 0.0086 16.5 0.0 1.2 1 0 0 1 1 1 1 Sterol carrier protein domain Lipoprotein_1 PF00820.19 CDJ90904.1 - 0.017 14.2 0.9 0.019 14.0 0.9 1.1 1 0 0 1 1 1 0 Borrelia lipoprotein An_peroxidase PF03098.15 CDJ90905.1 - 4.8e-217 721.7 0.0 6.3e-155 516.7 0.0 2.6 2 1 0 2 2 2 2 Animal haem peroxidase DUF2576 PF10845.8 CDJ90905.1 - 0.18 11.4 0.4 0.52 10.0 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) His_Phos_2 PF00328.22 CDJ90906.1 - 3.3e-23 82.7 1.0 6.7e-10 38.9 0.1 3.1 2 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.22 CDJ90906.1 - 0.0079 15.9 0.0 0.035 13.8 0.0 2.0 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) UQ_con PF00179.26 CDJ90907.1 - 6.2e-20 71.3 0.0 7.5e-20 71.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ90907.1 - 0.0011 18.7 0.0 0.0012 18.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B HTH_50 PF18024.1 CDJ90908.1 - 0.0014 18.2 0.0 0.0049 16.4 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain Malic_M PF03949.15 CDJ90909.1 - 3.1e-94 315.1 0.2 4.1e-94 314.6 0.2 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CDJ90909.1 - 1.4e-75 253.1 0.0 2.5e-75 252.3 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 CDJ90910.1 - 4.6e-95 317.8 0.0 5.7e-95 317.4 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CDJ90910.1 - 6.4e-75 250.9 0.0 1.1e-74 250.2 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain ATP-synt_F6 PF05511.11 CDJ90910.1 - 0.15 12.5 0.1 2.6 8.5 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 7TM_GPCR_Sra PF02117.16 CDJ90911.1 - 0.041 12.7 0.2 0.043 12.6 0.2 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sra ShK PF01549.24 CDJ90912.1 - 4.2e-06 27.2 6.4 3.1e-05 24.4 6.4 2.3 1 1 0 1 1 1 1 ShK domain-like Collagen PF01391.18 CDJ90913.1 - 4.1e-24 84.1 85.9 2.3e-05 24.1 6.6 4.3 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Collagen PF01391.18 CDJ90914.1 - 7.9e-62 204.9 250.3 8.7e-10 38.2 23.8 9.3 6 2 3 9 9 9 9 Collagen triple helix repeat (20 copies) Blt1 PF12754.7 CDJ90916.1 - 4.3e-06 27.1 4.0 0.029 14.7 0.3 2.1 1 1 0 2 2 2 2 Blt1 N-terminal domain GHMP_kinases_N PF00288.26 CDJ90916.1 - 0.0022 18.2 2.7 1.1 9.5 0.2 2.3 2 0 0 2 2 2 2 GHMP kinases N terminal domain Neocarzinostat PF00960.18 CDJ90916.1 - 0.039 13.9 1.5 3.1 7.8 0.1 2.1 2 0 0 2 2 2 0 Neocarzinostatin family vWF_A PF12450.8 CDJ90916.1 - 0.047 13.7 3.0 2.9 7.9 0.2 2.3 2 0 0 2 2 2 0 von Willebrand factor Ribosomal_L34 PF00468.17 CDJ90916.1 - 0.2 11.7 1.2 16 5.5 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein L34 PAC4 PF16093.5 CDJ90916.1 - 0.28 11.4 9.8 1 9.6 1.5 2.6 2 2 0 2 2 2 0 Proteasome assembly chaperone 4 VWA_N PF08399.11 CDJ90917.1 - 1.2e-10 42.0 3.1 6.5e-10 39.6 0.5 2.3 1 1 0 2 2 2 2 VWA N-terminal GATA PF00320.27 CDJ90918.1 - 1.2e-13 50.4 8.2 2.7e-13 49.3 8.2 1.7 1 0 0 1 1 1 1 GATA zinc finger Elf1 PF05129.13 CDJ90918.1 - 0.061 13.4 4.4 0.12 12.4 4.4 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like ArfGap PF01412.18 CDJ90918.1 - 0.092 12.8 5.1 0.12 12.5 4.9 1.3 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf eIF-5_eIF-2B PF01873.17 CDJ90918.1 - 0.19 11.6 5.2 0.34 10.8 5.2 1.3 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Na_H_Exchanger PF00999.21 CDJ90919.1 - 5.7e-74 249.2 38.5 2.9e-73 246.9 38.5 1.8 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Jagunal PF07086.12 CDJ90919.1 - 0.095 12.8 3.3 0.14 12.2 1.3 2.4 1 1 0 1 1 1 0 Jagunal, ER re-organisation during oogenesis GPR_Gpa2_C PF11970.8 CDJ90919.1 - 0.35 11.0 4.5 2.4 8.3 0.2 3.0 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term XhlA PF10779.9 CDJ90919.1 - 1.8 8.8 3.0 1.4 9.2 0.1 2.4 2 0 0 2 2 2 0 Haemolysin XhlA Bromodomain PF00439.25 CDJ90920.1 - 2.6e-42 142.8 6.2 3.5e-20 71.9 0.0 3.7 3 0 0 3 3 3 2 Bromodomain BET PF17035.5 CDJ90920.1 - 1.1e-20 73.6 0.3 1.1e-20 73.6 0.3 1.9 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation BRD4_CDT PF17105.5 CDJ90920.1 - 0.0021 17.6 5.4 0.0021 17.6 5.4 3.9 4 0 0 4 4 4 1 C-terminal domain of bromodomain protein 4 BRCT PF00533.26 CDJ90920.1 - 0.018 15.4 0.0 0.099 13.0 0.1 2.2 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain RecG_N PF17190.4 CDJ90920.1 - 0.037 14.7 0.2 0.18 12.5 0.2 2.2 1 0 0 1 1 1 0 RecG N-terminal helical domain T2SSM PF04612.12 CDJ90920.1 - 0.044 13.8 0.4 0.22 11.6 0.4 2.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Cg6151-P PF10233.9 CDJ90921.1 - 1.6e-29 102.5 9.9 1.9e-29 102.2 9.9 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF2781 PF10914.8 CDJ90921.1 - 0.028 14.8 0.7 0.038 14.4 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) 7TM_GPCR_Srz PF10325.9 CDJ90921.1 - 0.21 10.9 3.2 0.25 10.6 3.2 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz DUF5326 PF17260.2 CDJ90921.1 - 4 7.7 8.2 13 6.0 8.2 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5326) Deltameth_res PF16020.5 CDJ90921.1 - 7 6.6 6.8 3.3 7.6 0.2 2.7 2 1 0 2 2 2 0 Deltamethrin resistance Carb_anhydrase PF00194.21 CDJ90924.1 - 1.1e-77 261.1 0.0 1.2e-77 260.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase LIM PF00412.22 CDJ90925.1 - 1.1e-23 83.2 29.9 5.5e-12 45.7 8.4 2.9 3 0 0 3 3 3 2 LIM domain Homeodomain PF00046.29 CDJ90925.1 - 1.9e-17 62.9 4.8 3.4e-17 62.0 4.8 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ90925.1 - 1.5e-05 24.8 0.1 2.9e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Tox-REase-3 PF15647.6 CDJ90925.1 - 0.13 12.5 0.6 0.27 11.5 0.6 1.5 1 1 0 1 1 1 0 Restriction endonuclease fold toxin 3 HTH_32 PF13565.6 CDJ90925.1 - 0.15 12.7 0.3 0.27 11.9 0.3 1.4 1 0 0 1 1 1 0 Homeodomain-like domain FNIP_N PF14636.6 CDJ90925.1 - 0.34 11.9 5.7 0.082 13.9 2.7 1.4 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus Fanconi_A PF03511.14 CDJ90926.1 - 0.18 11.7 0.1 0.24 11.3 0.1 1.2 1 0 0 1 1 1 0 Fanconi anaemia group A protein Ras PF00071.22 CDJ90927.1 - 5.3e-34 117.1 0.0 7.1e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ90927.1 - 8e-11 42.2 0.0 1.5e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CDJ90927.1 - 0.0028 16.9 0.2 0.027 13.7 0.0 2.1 2 0 0 2 2 2 1 G-protein alpha subunit Arf PF00025.21 CDJ90927.1 - 0.0039 16.7 0.0 0.029 13.8 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.6 CDJ90927.1 - 0.095 13.0 0.0 1.4 9.2 0.0 2.7 2 1 0 2 2 2 0 AAA domain Glyco_tran_WbsX PF14307.6 CDJ90927.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase WbsX DAO PF01266.24 CDJ90928.1 - 2.6e-37 129.3 0.0 3.1e-37 129.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDJ90928.1 - 5.3e-05 23.4 0.2 0.00013 22.2 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 CDJ90928.1 - 0.00022 20.7 0.0 0.00031 20.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 CDJ90928.1 - 0.0005 19.3 0.0 0.0044 16.2 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 CDJ90928.1 - 0.00064 18.9 0.0 0.0013 17.9 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 CDJ90928.1 - 0.009 14.7 0.0 0.46 9.1 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 CDJ90928.1 - 0.012 14.9 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 CDJ90928.1 - 0.028 13.6 0.4 0.048 12.9 0.1 1.5 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 CDJ90928.1 - 0.06 12.6 0.2 0.85 8.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CDJ90928.1 - 0.062 12.5 0.0 0.15 11.3 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Neur_chan_memb PF02932.16 CDJ90930.1 - 1.5e-11 44.8 0.0 1.6e-11 44.7 0.0 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region MAM PF00629.23 CDJ90931.1 - 2.2e-06 27.7 0.0 0.058 13.3 0.0 2.7 2 1 0 2 2 2 2 MAM domain, meprin/A5/mu PHD PF00628.29 CDJ90932.1 - 0.00023 21.0 5.8 0.00049 19.9 5.8 1.6 1 0 0 1 1 1 1 PHD-finger TFIIA PF03153.13 CDJ90932.1 - 0.17 11.8 8.2 0.33 10.9 8.3 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING_2 PF13639.6 CDJ90932.1 - 0.58 10.5 6.9 0.97 9.8 6.9 1.4 1 0 0 1 1 1 0 Ring finger domain bZIP_2 PF07716.15 CDJ90933.1 - 1.8e-16 59.9 14.5 2.7e-16 59.4 14.5 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CDJ90933.1 - 6.5e-06 26.2 10.2 1.3e-05 25.2 10.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor PARM PF17061.5 CDJ90933.1 - 0.00029 21.1 0.0 0.00034 20.9 0.0 1.0 1 0 0 1 1 1 1 PARM bZIP_Maf PF03131.17 CDJ90933.1 - 0.012 16.1 6.5 0.021 15.3 6.5 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor HALZ PF02183.18 CDJ90933.1 - 0.013 15.7 0.7 0.022 15.0 0.7 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper TPD52 PF04201.15 CDJ90933.1 - 0.037 13.6 0.9 0.056 13.1 0.2 1.5 1 1 1 2 2 2 0 Tumour protein D52 family DUF1515 PF07439.11 CDJ90933.1 - 0.041 13.9 1.2 0.06 13.4 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Phlebovirus_NSM PF07246.11 CDJ90933.1 - 0.17 11.2 5.5 0.26 10.6 5.5 1.3 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M MAP17 PF15807.5 CDJ90933.1 - 2.2 8.5 5.5 3.3 8.0 4.5 1.8 1 1 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Arf PF00025.21 CDJ90934.1 - 8e-66 220.8 0.0 1e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CDJ90934.1 - 3.7e-11 43.3 0.0 5.8e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDJ90934.1 - 3.3e-10 39.8 0.0 5.1e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CDJ90934.1 - 5.7e-10 38.9 0.0 8e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CDJ90934.1 - 1.8e-08 34.0 0.3 5.5e-08 32.4 0.3 1.8 1 1 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.12 CDJ90934.1 - 5e-07 29.3 0.0 7e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDJ90934.1 - 0.00025 21.1 0.0 0.00045 20.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ArAE_2_N PF10337.9 CDJ90934.1 - 0.12 11.4 0.0 0.14 11.2 0.0 1.0 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DZR PF12773.7 CDJ90935.1 - 0.0025 17.8 8.4 0.0073 16.3 0.6 2.6 3 0 0 3 3 3 2 Double zinc ribbon zf-ribbon_3 PF13248.6 CDJ90935.1 - 0.036 13.5 0.7 2.1 7.9 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-dskA_traR PF01258.17 CDJ90935.1 - 0.058 13.3 0.5 7.5 6.6 0.2 2.7 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger RNA_POL_M_15KD PF02150.16 CDJ90935.1 - 0.15 12.0 2.7 0.16 11.8 0.2 2.2 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Nudix_N_2 PF14803.6 CDJ90935.1 - 0.17 11.8 0.2 0.17 11.8 0.2 2.5 3 0 0 3 3 3 0 Nudix N-terminal PknG_rubred PF16919.5 CDJ90935.1 - 0.23 11.6 2.1 2.5 8.3 0.2 2.3 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain NABP PF07990.12 CDJ90936.1 - 0.13 11.7 0.0 0.15 11.6 0.0 1.0 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Nodulin_late PF07127.11 CDJ90938.1 - 0.63 10.4 7.5 1.1 9.7 0.2 2.4 2 0 0 2 2 2 0 Late nodulin protein AAA_33 PF13671.6 CDJ90939.1 - 1.3e-09 38.3 0.0 3.9e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Smr PF01713.21 CDJ90939.1 - 2.6e-07 30.9 0.0 8.3e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.10 CDJ90939.1 - 0.00061 20.1 6.8 0.002 18.5 6.8 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Zeta_toxin PF06414.12 CDJ90939.1 - 0.0014 18.0 0.0 0.0081 15.5 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 CDJ90939.1 - 0.0016 19.0 0.3 0.041 14.4 0.0 3.0 4 0 0 4 4 4 1 AAA domain AAA_17 PF13207.6 CDJ90939.1 - 0.006 17.0 0.0 0.033 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 CDJ90939.1 - 0.0072 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 CDJ90939.1 - 0.0079 16.6 0.1 0.18 12.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.9 CDJ90939.1 - 0.036 13.3 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 CDJ90939.1 - 0.048 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI HemY_N PF07219.13 CDJ90939.1 - 1.3 9.3 3.1 2.6 8.3 3.1 1.4 1 0 0 1 1 1 0 HemY protein N-terminus Sds3 PF08598.11 CDJ90940.1 - 3e-14 53.5 2.9 3.4e-14 53.4 2.9 1.1 1 0 0 1 1 1 1 Sds3-like DUF1344 PF07076.11 CDJ90940.1 - 0.17 11.8 0.9 0.98 9.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) CENP-O PF09496.10 CDJ90940.1 - 0.24 11.3 4.5 0.37 10.7 2.5 1.9 2 0 0 2 2 2 0 Cenp-O kinetochore centromere component PspB PF06667.12 CDJ90940.1 - 0.63 10.1 5.4 0.38 10.8 2.0 2.0 2 0 0 2 2 2 0 Phage shock protein B Mitofilin PF09731.9 CDJ90940.1 - 2.6 6.8 12.1 3.5 6.3 12.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Mito_carr PF00153.27 CDJ90941.1 - 4.5e-46 154.7 5.4 7.4e-19 67.5 0.2 4.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CDJ90941.1 - 0.0084 15.3 0.8 0.15 11.2 0.8 2.2 1 1 0 1 1 1 1 Gammaproteobacterial serine protease SPP PF06550.11 CDJ90942.1 - 0.012 15.1 1.0 0.017 14.6 1.0 1.1 1 0 0 1 1 1 0 Signal-peptide peptidase, presenilin aspartyl protease L6_membrane PF05805.12 CDJ90942.1 - 0.072 12.7 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 L6 membrane protein PsbT PF01405.17 CDJ90942.1 - 0.19 11.6 0.6 0.35 10.7 0.6 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TMEM144 PF07857.12 CDJ90944.1 - 1.4e-128 428.6 15.9 1.6e-128 428.4 15.9 1.0 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 CDJ90944.1 - 1.5e-09 37.6 20.2 3.8e-09 36.3 4.0 3.0 2 2 1 3 3 3 2 Sugar transport protein NDUF_C2 PF06374.11 CDJ90944.1 - 0.041 14.0 0.1 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) DUF2499 PF10693.9 CDJ90944.1 - 0.14 12.4 3.3 1.3 9.4 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2499) Hat1_N PF10394.9 CDJ90945.1 - 7.7e-36 123.7 0.8 1.6e-34 119.4 0.9 2.1 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 CDJ90945.1 - 6.2e-05 23.2 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDJ90945.1 - 0.037 14.5 0.0 0.068 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 CDJ90945.1 - 0.061 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_10 PF13673.7 CDJ90945.1 - 0.1 12.5 0.0 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain fn3 PF00041.21 CDJ90947.1 - 1.3e-28 99.2 0.2 1.3e-09 38.2 0.1 3.3 3 0 0 3 3 3 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CDJ90947.1 - 2.3e-05 24.9 0.5 0.49 11.0 0.1 3.5 3 2 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 CDJ90947.1 - 0.03 14.6 0.0 7.8 6.9 0.0 3.1 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III Abhydro_lipase PF04083.16 CDJ90948.1 - 9e-22 76.4 0.1 1.7e-21 75.6 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 CDJ90948.1 - 6e-16 58.9 0.1 6e-15 55.6 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ90948.1 - 2.4e-06 28.3 0.0 3.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDJ90948.1 - 2.5e-05 23.7 0.0 0.00033 20.0 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF900 PF05990.12 CDJ90948.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) BTB_2 PF02214.22 CDJ90950.1 - 1.7e-18 66.8 0.1 2.5e-18 66.2 0.1 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 CDJ90950.1 - 0.00048 20.2 0.0 0.00089 19.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain WD40_3 PF15911.5 CDJ90950.1 - 0.033 14.2 0.1 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 WD domain, G-beta repeat BTB_2 PF02214.22 CDJ90951.1 - 3.5e-14 52.9 0.0 6.9e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 CDJ90951.1 - 0.028 14.6 0.0 0.077 13.2 0.0 1.6 2 0 0 2 2 2 0 BTB/POZ domain DUF2417 PF10329.9 CDJ90952.1 - 0.051 13.0 0.0 0.063 12.7 0.0 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Glypican PF01153.19 CDJ90952.1 - 0.095 11.5 0.0 0.12 11.2 0.0 1.0 1 0 0 1 1 1 0 Glypican RcnB PF11776.8 CDJ90954.1 - 0.027 14.5 0.0 0.037 14.1 0.0 1.2 1 0 0 1 1 1 0 Nickel/cobalt transporter regulator CDP-OH_P_tran_2 PF08009.11 CDJ90954.1 - 0.046 13.6 0.1 0.067 13.1 0.1 1.2 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase 2 CAP PF00188.26 CDJ90957.1 - 1.1e-12 48.9 2.2 1.7e-12 48.2 2.2 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ90957.1 - 0.071 13.4 1.8 0.31 11.3 1.8 2.0 1 1 0 1 1 1 0 Ancylostoma-associated secreted protein related CAP PF00188.26 CDJ90958.1 - 5.4e-19 69.3 5.7 9.5e-19 68.5 5.7 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ90958.1 - 0.0033 17.7 0.1 0.0053 17.0 0.1 1.5 1 0 0 1 1 1 1 Ancylostoma-associated secreted protein related Metallothio PF00131.20 CDJ90958.1 - 2.1 8.5 25.2 0.95 9.7 6.2 3.1 3 0 0 3 3 3 0 Metallothionein Metallothio_Euk PF12749.7 CDJ90958.1 - 7.3 6.8 27.2 4.3 7.6 6.3 2.9 3 1 0 3 3 3 0 Eukaryotic metallothionein Kinesin PF00225.23 CDJ90959.1 - 5e-110 367.5 1.3 1.7e-109 365.8 1.3 1.9 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ90959.1 - 1.6e-27 96.3 0.1 1.6e-27 96.3 0.1 2.8 3 1 0 3 3 3 1 Microtubule binding TMF_DNA_bd PF12329.8 CDJ90959.1 - 0.01 15.8 15.6 0.01 15.8 15.6 5.6 4 3 2 6 6 6 0 TATA element modulatory factor 1 DNA binding HALZ PF02183.18 CDJ90959.1 - 3.8 7.8 13.2 6.1 7.2 0.6 4.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper PT-VENN PF04829.13 CDJ90960.1 - 0.08 13.0 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif zf-C3HC4_3 PF13920.6 CDJ90961.1 - 9.2e-05 22.2 2.9 0.00017 21.4 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ90961.1 - 0.0003 20.7 3.5 0.00071 19.5 3.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CDJ90961.1 - 0.0013 18.5 4.2 0.0029 17.4 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ90961.1 - 0.0016 18.3 4.3 0.0034 17.2 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDJ90961.1 - 0.0019 18.0 4.6 0.0037 17.1 4.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CDJ90961.1 - 0.011 15.7 5.2 0.025 14.6 5.2 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 CDJ90961.1 - 0.044 14.1 0.9 0.12 12.7 0.9 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 CDJ90961.1 - 0.13 12.4 2.7 0.34 11.1 2.7 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 CDJ90961.1 - 0.13 12.3 0.9 0.27 11.3 0.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CDJ90961.1 - 0.14 12.5 4.6 0.33 11.3 4.6 1.7 1 0 0 1 1 1 0 Ring finger domain VBS PF08913.10 CDJ90961.1 - 0.47 10.9 4.7 6.9 7.1 0.2 3.1 2 1 0 3 3 3 0 Vinculin Binding Site LPP PF04728.13 CDJ90961.1 - 0.94 9.9 13.5 3.6 8.1 0.2 5.6 5 1 0 5 5 5 0 Lipoprotein leucine-zipper DUF501 PF04417.12 CDJ90961.1 - 5.1 6.9 9.4 14 5.4 1.5 3.5 2 1 0 3 3 3 0 Protein of unknown function (DUF501) DUF2911 PF11138.8 CDJ90961.1 - 5.4 6.9 6.5 2.9 7.7 0.1 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2911) Thioredoxin_6 PF13848.6 CDJ90962.1 - 1.9e-11 44.2 0.2 5.7e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin PF00085.20 CDJ90962.1 - 0.0052 16.8 0.0 0.038 14.0 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin DUF2847 PF11009.8 CDJ90962.1 - 0.022 14.6 0.2 0.092 12.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2847) Ribosomal_S3Ae PF01015.18 CDJ90964.1 - 4.2e-87 291.0 1.6 4.9e-87 290.7 1.6 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family AroM PF07302.11 CDJ90964.1 - 0.16 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 AroM protein EIF4E-T PF10477.9 CDJ90965.1 - 3.1e-17 62.7 9.8 4.7e-14 52.2 4.7 3.1 1 1 1 2 2 2 2 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF1907 PF08925.11 CDJ90966.1 - 5.9e-101 337.6 0.1 6.8e-101 337.4 0.1 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) DUF1758 PF05585.12 CDJ90967.1 - 4.9e-11 42.7 0.0 1.1e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) RVT_1 PF00078.27 CDJ90967.1 - 1.9e-07 30.9 0.0 4.4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CDJ90967.1 - 2e-05 25.1 0.0 5.5e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ90967.1 - 0.00086 19.9 0.0 0.0017 18.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CDJ90967.1 - 0.033 14.0 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP PF00077.20 CDJ90967.1 - 0.063 13.6 0.0 0.16 12.3 0.0 1.7 2 0 0 2 2 2 0 Retroviral aspartyl protease NHL PF01436.21 CDJ90968.1 - 3.8e-38 127.6 12.8 3.6e-11 42.5 0.2 5.6 5 0 0 5 5 5 5 NHL repeat SGL PF08450.12 CDJ90968.1 - 8.6e-09 35.3 0.3 0.018 14.6 0.0 3.2 1 1 2 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region zf-B_box PF00643.24 CDJ90968.1 - 4e-08 33.3 28.2 6.9e-07 29.3 7.2 4.4 3 1 0 3 3 2 2 B-box zinc finger zf-RING_UBOX PF13445.6 CDJ90968.1 - 2.1e-07 30.8 7.1 2.1e-07 30.8 7.1 3.5 3 0 0 3 3 1 1 RING-type zinc-finger DUF5128 PF17170.4 CDJ90968.1 - 9e-07 28.3 2.1 0.00021 20.5 0.1 2.9 2 1 1 3 3 3 2 6-bladed beta-propeller zf-C3HC4 PF00097.25 CDJ90968.1 - 1.9e-06 27.7 9.1 1.9e-06 27.7 9.1 3.7 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ90968.1 - 7.2e-06 25.9 9.9 7.2e-06 25.9 9.9 3.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CDJ90968.1 - 1.1e-05 25.1 10.0 1.1e-05 25.1 10.0 3.5 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ90968.1 - 0.00012 22.2 10.2 0.00012 22.2 10.2 4.0 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 CDJ90968.1 - 0.0064 16.3 8.2 0.017 14.9 8.2 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF4934 PF16288.5 CDJ90968.1 - 0.016 15.1 0.7 2 8.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4934) KIP1 PF07765.12 CDJ90968.1 - 0.05 13.7 0.9 0.1 12.7 0.3 1.8 1 1 0 1 1 1 0 KIP1-like protein PhaP_Bmeg PF09602.10 CDJ90968.1 - 0.17 11.8 2.8 0.29 11.1 2.8 1.3 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Cytokin-bind PF09265.10 CDJ90968.1 - 0.25 10.7 1.0 0.43 9.9 1.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Sigma70_ner PF04546.13 CDJ90968.1 - 0.27 11.1 2.9 0.44 10.4 2.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF3450 PF11932.8 CDJ90968.1 - 0.45 9.8 5.8 0.7 9.2 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Baculo_PEP_C PF04513.12 CDJ90968.1 - 0.98 9.5 3.6 2.2 8.3 3.6 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PY_rept_46 PF09689.10 CDJ90969.1 - 0.17 12.5 0.7 1.3 9.6 1.0 2.2 2 0 0 2 2 2 0 Plasmodium yoelii repeat (PY_rept_46) rve PF00665.26 CDJ90971.1 - 0.019 15.2 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain DUF643 PF04867.12 CDJ90971.1 - 0.053 14.1 0.1 3 8.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF643) zf-H2C2_2 PF13465.6 CDJ90972.1 - 4.5e-14 52.1 21.4 2.7e-07 30.7 0.2 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 CDJ90972.1 - 1.1e-11 44.5 20.2 0.001 19.4 1.9 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ90972.1 - 1.8e-10 40.8 15.7 0.00081 20.0 0.9 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ90972.1 - 2.9e-07 30.6 2.7 0.0066 16.7 0.2 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDJ90972.1 - 1.8e-05 25.0 3.1 0.019 15.3 0.0 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 CDJ90972.1 - 4.9e-05 22.9 2.4 0.11 12.2 0.1 2.9 1 1 2 3 3 3 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-Di19 PF05605.12 CDJ90972.1 - 0.00048 20.4 2.2 0.076 13.3 1.3 2.5 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 CDJ90972.1 - 0.00081 19.3 13.5 0.017 15.1 0.8 3.9 3 1 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CDJ90972.1 - 0.0023 17.7 1.9 0.0023 17.7 1.9 3.1 3 0 0 3 3 3 1 C2H2-type zinc-finger domain Cwf_Cwc_15 PF04889.12 CDJ90972.1 - 0.064 13.0 4.1 0.15 11.8 4.1 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-C2H2_2 PF12756.7 CDJ90972.1 - 0.3 11.4 5.5 7.1 7.0 0.5 2.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF2225 PF09986.9 CDJ90972.1 - 0.41 10.3 4.3 1.4 8.6 4.2 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-BED PF02892.15 CDJ90972.1 - 0.81 9.8 10.8 0.87 9.7 0.1 3.3 2 1 1 3 3 3 0 BED zinc finger PHD PF00628.29 CDJ90972.1 - 1.2 9.1 4.7 9.3 6.2 0.8 2.4 2 0 0 2 2 2 0 PHD-finger Zn-ribbon_8 PF09723.10 CDJ90972.1 - 1.2 9.3 6.3 1.5 9.0 1.0 2.6 1 1 1 2 2 2 0 Zinc ribbon domain C1_2 PF03107.16 CDJ90972.1 - 2.5 8.5 8.8 14 6.1 2.8 3.1 2 1 0 2 2 2 0 C1 domain zf-FCS PF06467.14 CDJ90972.1 - 7.7 6.5 6.3 3 7.8 1.9 2.5 2 1 1 3 3 3 0 MYM-type Zinc finger with FCS sequence motif Sre PF03125.18 CDJ90973.1 - 2.4e-06 27.0 0.4 2.7e-06 26.8 0.4 1.2 1 0 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor 7TM_GPCR_Srab PF10292.9 CDJ90973.1 - 0.00033 19.7 0.8 0.00037 19.5 0.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor Syndecan PF01034.20 CDJ90973.1 - 0.71 9.8 2.5 11 6.1 0.6 2.6 2 1 0 2 2 2 0 Syndecan domain Transposase_1 PF01359.18 CDJ90974.1 - 0.0018 18.1 0.1 0.0059 16.4 0.1 1.9 2 0 0 2 2 2 1 Transposase (partial DDE domain) DDE_3 PF13358.6 CDJ90974.1 - 0.0023 17.7 0.1 0.0032 17.2 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RITA PF17066.5 CDJ90974.1 - 0.12 11.9 0.8 0.18 11.4 0.8 1.2 1 0 0 1 1 1 0 RBPJ-interacting and tubulin associated protein Adeno_E3_CR2 PF02439.15 CDJ90975.1 - 0.025 14.3 0.6 0.036 13.8 0.6 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Elf1 PF05129.13 CDJ90976.1 - 4.5 7.4 9.6 3.3 7.8 0.3 3.0 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Acyl_transf_3 PF01757.22 CDJ90978.1 - 1.2e-26 93.6 27.8 1.2e-26 93.6 27.8 1.5 2 0 0 2 2 2 1 Acyltransferase family SAM_2 PF07647.17 CDJ90979.1 - 2.4e-05 24.4 0.0 5.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CDJ90979.1 - 0.00014 22.2 0.0 0.00027 21.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Glyoxalase PF00903.25 CDJ90981.1 - 7.1e-13 48.9 0.0 7.6e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CDJ90981.1 - 4e-06 27.1 0.0 5.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 CDJ90981.1 - 0.0046 17.7 0.0 0.0049 17.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 CDJ90981.1 - 0.049 13.6 0.0 0.087 12.8 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain TxDE PF18711.1 CDJ90981.1 - 0.053 13.7 0.0 0.25 11.5 0.0 1.9 2 0 0 2 2 2 0 Toxoflavin-degrading enzyme Glyoxalase_3 PF13468.6 CDJ90981.1 - 0.055 13.6 0.0 0.095 12.8 0.0 1.4 2 0 0 2 2 2 0 Glyoxalase-like domain UDPGT PF00201.18 CDJ90982.1 - 1.7e-39 136.0 0.0 2.1e-39 135.7 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ90982.1 - 2.8e-11 43.7 0.0 3.9e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 CDJ90982.1 - 0.017 14.4 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 HemY_N PF07219.13 CDJ90982.1 - 0.36 11.1 1.1 0.65 10.2 1.1 1.3 1 0 0 1 1 1 0 HemY protein N-terminus UDPGT PF00201.18 CDJ90983.1 - 1.2e-37 129.9 0.0 1.3e-37 129.8 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ90983.1 - 3e-09 37.1 0.0 6.4e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 CDJ90983.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 Stn1_C PF12659.7 CDJ90983.1 - 0.17 11.9 0.3 0.36 10.8 0.0 1.6 2 0 0 2 2 2 0 Telomere capping C-terminal wHTH Glyco_transf_4 PF13439.6 CDJ90983.1 - 0.18 11.8 0.0 0.7 9.9 0.0 1.9 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Recep_L_domain PF01030.24 CDJ90984.1 - 0.0021 18.2 0.0 0.0049 17.0 0.0 1.6 1 0 0 1 1 1 1 Receptor L domain RIFIN PF02009.16 CDJ90984.1 - 1.9 8.3 7.6 1.2 9.0 6.2 1.4 1 1 0 1 1 1 0 Rifin Sugar_tr PF00083.24 CDJ90985.1 - 9.5e-106 354.4 33.9 8.4e-83 278.7 17.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CDJ90985.1 - 9.9e-28 97.1 24.4 9.1e-26 90.6 18.2 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Y_phosphatase PF00102.27 CDJ90985.1 - 9.6e-17 61.3 0.0 1.7e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase TRI12 PF06609.13 CDJ90985.1 - 0.00096 17.7 4.7 0.00096 17.7 4.7 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) COX7B PF05392.11 CDJ90985.1 - 8.2 6.2 6.5 19 5.0 0.4 2.8 2 0 0 2 2 2 0 Cytochrome C oxidase chain VIIB SLC12 PF03522.15 CDJ90986.1 - 1.8e-87 294.2 0.0 4.5e-60 203.9 0.0 2.1 1 1 0 2 2 2 2 Solute carrier family 12 AA_permease PF00324.21 CDJ90986.1 - 1.5e-69 234.9 18.6 1.8e-69 234.6 18.6 1.1 1 0 0 1 1 1 1 Amino acid permease Glyco_trans_1_4 PF13692.6 CDJ90986.1 - 0.16 12.4 0.0 0.85 10.1 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferases group 1 DUF5409 PF17421.2 CDJ90986.1 - 0.24 12.1 1.9 0.58 10.9 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5409) HAUS5 PF14817.6 CDJ90988.1 - 0.0057 15.5 1.1 0.0072 15.1 1.1 1.3 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 5 RXLR PF16810.5 CDJ90988.1 - 0.02 15.3 0.4 0.02 15.3 0.4 1.4 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity DUF3499 PF12005.8 CDJ90988.1 - 0.17 12.5 3.4 1.3 9.7 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3499) HBS1_N PF08938.10 CDJ90988.1 - 1.4 9.3 7.1 2.3 8.6 1.8 2.5 2 1 0 2 2 2 0 HBS1 N-terminus Sulfate_transp PF00916.20 CDJ90989.1 - 2.7e-106 355.5 22.7 3.8e-106 355.1 22.7 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CDJ90989.1 - 2.8e-26 91.5 0.0 5e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 STAS domain TMEMspv1-c74-12 PF11044.8 CDJ90989.1 - 0.06 13.3 1.4 0.21 11.6 1.4 1.9 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein MFS_MOT1 PF16983.5 CDJ90989.1 - 0.48 10.8 8.4 0.22 12.0 3.4 2.7 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily PAP2 PF01569.21 CDJ90989.1 - 3 7.6 17.2 1.1 9.1 3.9 3.7 2 1 1 3 3 3 0 PAP2 superfamily Collagen PF01391.18 CDJ90990.1 - 6.7e-27 93.0 90.1 1.5e-09 37.5 32.7 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ90990.1 - 1.4e-13 50.7 0.9 1.8e-13 50.3 0.9 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain eIF-3c_N PF05470.12 CDJ90991.1 - 2.9e-208 693.0 38.1 9.2e-207 688.0 38.1 2.2 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 CDJ90991.1 - 2.6e-16 60.1 0.5 2.6e-16 60.1 0.5 2.7 2 1 1 3 3 3 1 PCI domain Nucleolin_bd PF16725.5 CDJ90991.1 - 0.23 11.2 2.5 6.8 6.4 0.1 3.1 3 0 0 3 3 3 0 Nucleolin binding domain Asp PF00026.23 CDJ90992.1 - 3.9e-88 295.9 2.7 4.7e-88 295.6 2.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ90992.1 - 1.6e-11 44.7 6.2 1.6e-11 44.7 6.2 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ90992.1 - 0.00015 21.6 0.0 0.0016 18.3 0.0 2.3 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CDJ90992.1 - 0.0012 19.4 0.1 1.5 9.5 0.0 3.1 3 0 0 3 3 3 2 Aspartyl protease BRCT PF00533.26 CDJ90994.1 - 3.4e-45 152.3 0.0 8e-10 39.0 0.0 6.5 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CDJ90994.1 - 2.6e-41 139.4 5.7 8.1e-17 60.9 0.1 6.0 5 0 0 5 5 5 5 twin BRCT domain BRCT_2 PF16589.5 CDJ90994.1 - 8.9e-35 119.0 0.0 1e-06 29.0 0.0 6.9 6 0 0 6 6 6 6 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 CDJ90994.1 - 1.4e-13 50.8 0.1 0.0015 18.6 0.0 5.3 5 0 0 5 5 5 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CDJ90994.1 - 9e-11 41.9 0.7 0.033 14.5 0.1 5.9 6 0 0 6 6 6 3 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 CDJ90994.1 - 6e-06 26.1 0.0 0.0086 15.9 0.0 4.6 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain DUF4505 PF14956.6 CDJ90995.1 - 3.1e-60 203.0 3.2 3.7e-60 202.7 3.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4505) NDUFB10 PF10249.9 CDJ90996.1 - 9.9e-49 165.0 0.5 1.6e-48 164.4 0.5 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 KH_6 PF15985.5 CDJ90997.1 - 5.2e-16 58.7 0.1 8.5e-16 58.0 0.1 1.4 1 0 0 1 1 1 1 KH domain DUF3987 PF13148.6 CDJ90998.1 - 0.037 13.0 0.1 0.048 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Hormone_recep PF00104.30 CDJ90998.1 - 0.1 12.2 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor UPF0172 PF03665.13 CDJ91000.1 - 9.8e-25 87.7 0.0 2.2e-24 86.6 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) PX PF00787.24 CDJ91000.1 - 7.6e-19 67.8 0.1 1.8e-18 66.5 0.1 1.7 1 0 0 1 1 1 1 PX domain PDZ PF00595.24 CDJ91000.1 - 3.2e-14 53.0 0.4 6.6e-14 52.0 0.4 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDJ91000.1 - 1.3e-12 47.4 0.4 3.4e-12 46.0 0.4 1.8 1 0 0 1 1 1 1 PDZ domain RA PF00788.23 CDJ91000.1 - 5.9e-06 26.8 0.1 1.8e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PDZ_2 PF13180.6 CDJ91000.1 - 0.0013 19.0 0.0 0.0039 17.5 0.0 1.8 1 0 0 1 1 1 1 PDZ domain CAP PF00188.26 CDJ91001.1 - 1e-20 74.9 7.2 1.6e-20 74.2 7.2 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TT_ORF2 PF02957.15 CDJ91001.1 - 0.041 14.8 2.9 0.074 14.0 2.9 1.5 1 0 0 1 1 1 0 TT viral ORF2 Comm PF15957.5 CDJ91002.1 - 0.012 15.9 0.1 0.014 15.8 0.1 1.1 1 0 0 1 1 1 0 Commissureless rve PF00665.26 CDJ91003.1 - 6e-16 58.7 0.1 1.8e-15 57.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 CDJ91003.1 - 3.6e-05 23.5 0.8 6.3e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 CDJ91004.1 - 1.6e-19 70.3 0.0 2.8e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDJ91004.1 - 1.8e-16 60.0 0.0 5.3e-16 58.5 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 CDJ91004.1 - 1.4e-08 35.2 0.0 3.1e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ91004.1 - 5.8e-08 33.3 0.0 1.4e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 CDJ91004.1 - 4e-06 27.1 0.0 8.8e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP PF00077.20 CDJ91004.1 - 1.1e-05 25.7 0.0 3e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Myb_CC_LHEQLE PF14379.6 CDJ91005.1 - 0.0036 17.0 2.2 0.0072 16.0 2.2 1.5 1 0 0 1 1 1 1 MYB-CC type transfactor, LHEQLE motif RIH_assoc PF08454.11 CDJ91005.1 - 0.005 16.7 0.0 0.0054 16.6 0.0 1.3 1 0 0 1 1 1 1 RyR and IP3R Homology associated TolA_bind_tri PF16331.5 CDJ91005.1 - 0.015 15.4 1.2 0.025 14.6 1.2 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation Spore_III_AB PF09548.10 CDJ91005.1 - 0.022 14.8 0.8 0.052 13.6 0.8 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Apo-CIII PF05778.12 CDJ91005.1 - 0.058 13.0 0.3 0.092 12.4 0.3 1.4 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) DUF1940 PF09155.10 CDJ91006.1 - 0.018 15.1 1.4 0.027 14.6 0.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1940) HalX PF08663.10 CDJ91006.1 - 0.061 13.7 1.8 0.061 13.7 1.8 2.4 2 1 0 2 2 2 0 HalX domain TPR_MLP1_2 PF07926.12 CDJ91006.1 - 0.062 13.4 27.1 0.049 13.7 7.1 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein THOC7 PF05615.13 CDJ91006.1 - 0.33 11.2 21.0 0.12 12.6 8.5 2.6 1 1 1 2 2 2 0 Tho complex subunit 7 DUF812 PF05667.11 CDJ91006.1 - 0.38 9.6 20.4 0.49 9.2 20.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) bVLRF1 PF18826.1 CDJ91006.1 - 0.49 10.3 4.9 0.14 12.0 0.7 2.1 2 1 1 3 3 3 0 bacteroidetes VLRF1 release factor Vir_act_alpha_C PF10400.9 CDJ91006.1 - 3.1 8.5 11.3 17 6.2 0.0 3.0 3 1 0 3 3 3 0 Virulence activator alpha C-term SlyX PF04102.12 CDJ91006.1 - 4.3 8.0 12.9 1.4 9.6 3.8 3.5 3 2 1 4 4 4 0 SlyX DUF4407 PF14362.6 CDJ91006.1 - 4.5 6.5 13.0 31 3.8 13.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 CDJ91006.1 - 6.3 6.9 24.8 1.3 9.1 12.1 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Rootletin PF15035.6 CDJ91006.1 - 9 6.3 25.7 0.31 11.0 12.8 2.6 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion COesterase PF00135.28 CDJ91007.1 - 2e-72 244.7 0.0 2.5e-72 244.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 CDJ91007.1 - 2.6e-06 28.2 0.1 4.2e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CDJ91007.1 - 1.5e-05 25.0 0.0 4.2e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 CDJ91007.1 - 0.0021 17.8 0.1 0.0088 15.7 0.1 1.9 1 1 0 1 1 1 1 Putative esterase Lipase_3 PF01764.25 CDJ91007.1 - 0.024 14.5 0.0 0.052 13.4 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.12 CDJ91007.1 - 0.14 10.8 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Exo_endo_phos_2 PF14529.6 CDJ91008.1 - 0.0017 18.2 0.0 0.0024 17.7 0.0 1.3 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ91008.1 - 0.022 14.3 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Exo70 PF03081.15 CDJ91008.1 - 0.093 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Exo70 exocyst complex subunit adh_short_C2 PF13561.6 CDJ91009.1 - 9e-59 198.9 0.3 1.1e-58 198.6 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDJ91009.1 - 1.1e-46 158.8 0.2 1.6e-46 158.3 0.2 1.2 1 1 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.10 CDJ91009.1 - 0.019 14.4 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) F420_oxidored PF03807.17 CDJ91009.1 - 0.028 15.0 0.1 0.071 13.7 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glyco_hydro_10 PF00331.20 CDJ91009.1 - 0.15 11.2 0.0 0.29 10.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 Metallophos PF00149.28 CDJ91010.1 - 5.3e-34 118.5 0.2 8.5e-34 117.8 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDJ91010.1 - 0.0024 18.3 0.0 0.005 17.3 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 CDJ91010.1 - 0.045 13.9 0.0 0.068 13.4 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain BLM10_mid PF16507.5 CDJ91012.1 - 2.7e-33 115.4 13.7 1.1e-16 60.6 1.2 3.9 4 0 0 4 4 4 3 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 CDJ91012.1 - 3.1e-19 68.7 0.0 2.2e-18 66.0 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT_2 PF13646.6 CDJ91012.1 - 0.00021 21.6 2.3 3 8.3 0.0 4.6 3 1 0 4 4 4 1 HEAT repeats Cnd1 PF12717.7 CDJ91012.1 - 0.006 16.6 11.0 0.0062 16.6 0.5 4.8 6 0 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CDJ91012.1 - 6 7.4 7.5 6.8 7.2 0.2 4.6 6 0 0 6 6 6 0 HEAT repeat BLM10_mid PF16507.5 CDJ91013.1 - 2.2e-39 135.5 14.9 9.5e-24 83.9 0.4 3.9 2 1 0 2 2 2 2 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 CDJ91013.1 - 6.4e-19 67.7 0.0 3.4e-18 65.3 0.0 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) TRAPP PF04051.16 CDJ91013.1 - 0.044 13.5 1.3 2.3 7.9 0.2 3.0 3 0 0 3 3 3 0 Transport protein particle (TRAPP) component CFIA_Pcf11 PF11526.8 CDJ91013.1 - 0.082 13.4 0.1 3.8 8.1 0.0 2.6 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 RT_RNaseH_2 PF17919.1 CDJ91014.1 - 5.6e-26 90.5 0.0 1.1e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ91014.1 - 2.1e-25 89.0 0.1 4.1e-25 88.1 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ91014.1 - 5.7e-16 58.7 0.0 1.9e-15 57.0 0.0 1.9 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ91014.1 - 6.1e-14 51.9 0.0 1.2e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain DNA_pol_viral_C PF00336.18 CDJ91014.1 - 0.02 14.3 0.0 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain AAA_12 PF13087.6 CDJ91015.1 - 1.9e-33 115.8 0.0 2.8e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ91015.1 - 1.4e-07 31.4 0.3 0.011 15.4 0.2 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CDJ91015.1 - 4.7e-07 30.2 0.0 1.6e-06 28.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ91015.1 - 9.3e-06 25.6 0.6 0.0025 17.6 0.2 3.1 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CDJ91015.1 - 0.0046 16.7 0.1 0.062 13.0 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 CDJ91015.1 - 0.011 15.2 0.0 0.098 12.1 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein Helicase_RecD PF05127.14 CDJ91015.1 - 0.88 9.4 2.4 13 5.6 0.2 2.8 3 0 0 3 3 3 0 Helicase DUF3437 PF11919.8 CDJ91016.1 - 1.1e-15 57.3 0.0 3.1e-15 55.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) Adaptin_N PF01602.20 CDJ91016.1 - 0.011 14.3 0.1 0.027 13.1 0.0 1.6 2 0 0 2 2 2 0 Adaptin N terminal region A_deaminase PF00962.22 CDJ91017.1 - 4.9e-13 49.1 0.0 6.7e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase eIF_4EBP PF05456.11 CDJ91017.1 - 0.044 13.7 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Pyr_redox_2 PF07992.14 CDJ91018.1 - 2.5e-51 174.7 0.0 3.2e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CDJ91018.1 - 9.3e-28 96.7 0.0 1.8e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CDJ91018.1 - 9e-15 55.0 1.8 1.4e-11 44.8 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CDJ91018.1 - 7.2e-08 32.0 0.1 3.1e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CDJ91018.1 - 5e-06 25.8 4.1 2.2e-05 23.8 2.8 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 CDJ91018.1 - 5.3e-05 22.6 0.1 0.0001 21.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 CDJ91018.1 - 0.00018 21.0 1.1 0.00033 20.1 1.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 CDJ91018.1 - 0.00019 20.8 0.0 0.012 15.0 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 CDJ91018.1 - 0.0023 17.6 0.9 0.02 14.5 0.4 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CDJ91018.1 - 0.0027 16.5 0.7 0.0054 15.5 0.4 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 CDJ91018.1 - 0.0067 16.6 4.2 0.013 15.8 0.5 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CDJ91018.1 - 0.0092 15.1 0.9 0.016 14.3 0.9 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A K_oxygenase PF13434.6 CDJ91018.1 - 0.014 14.5 0.1 0.71 8.9 0.0 2.6 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) PS_pyruv_trans PF04230.13 CDJ91018.1 - 0.016 15.2 0.0 0.092 12.7 0.0 2.0 1 1 1 2 2 2 0 Polysaccharide pyruvyl transferase Glyco_transf_4 PF13439.6 CDJ91018.1 - 0.07 13.1 0.0 0.83 9.6 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase Family 4 XdhC_C PF13478.6 CDJ91018.1 - 0.21 12.1 0.4 23 5.5 0.0 2.6 2 1 0 2 2 2 0 XdhC Rossmann domain DDRGK PF09756.9 CDJ91019.1 - 9.9e-59 198.1 30.0 1.6e-58 197.4 30.0 1.3 1 0 0 1 1 1 1 DDRGK domain FeoC PF09012.10 CDJ91019.1 - 0.0011 19.0 0.4 0.57 10.3 0.0 2.9 3 0 0 3 3 3 2 FeoC like transcriptional regulator DUF3347 PF11827.8 CDJ91019.1 - 0.27 11.4 6.5 0.43 10.8 6.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Rrn6 PF10214.9 CDJ91019.1 - 0.29 9.6 2.2 0.32 9.5 2.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DDE_Tnp_ISL3 PF01610.17 CDJ91019.1 - 0.31 10.7 10.0 0.55 9.9 10.0 1.3 1 0 0 1 1 1 0 Transposase DAPDH_C PF16654.5 CDJ91019.1 - 1.2 9.0 3.7 0.85 9.5 1.8 1.7 1 1 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain Atg14 PF10186.9 CDJ91019.1 - 2.5 7.1 8.4 3.6 6.6 8.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_11 PF13086.6 CDJ91019.1 - 2.6 7.7 10.7 3.9 7.2 10.7 1.4 1 0 0 1 1 1 0 AAA domain PA26 PF04636.13 CDJ91019.1 - 2.7 6.8 9.0 3.5 6.4 9.0 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Peptidase_S28 PF05577.12 CDJ91020.1 - 4.4e-142 473.9 3.0 4.4e-142 473.9 3.0 1.4 2 0 0 2 2 2 1 Serine carboxypeptidase S28 MADF_DNA_bdg PF10545.9 CDJ91020.1 - 7.4e-08 32.6 1.0 3.9e-07 30.3 1.0 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Peptidase_S28 PF05577.12 CDJ91021.1 - 1.7e-20 73.3 0.1 2.2e-20 72.9 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 RRM_1 PF00076.22 CDJ91021.1 - 0.0027 17.5 0.0 0.0064 16.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDJ91021.1 - 0.0068 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 CDJ91021.1 - 0.14 12.1 0.0 0.44 10.5 0.0 2.0 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-C2H2 PF00096.26 CDJ91022.1 - 5.2e-09 36.1 57.3 0.017 15.5 2.4 8.4 8 0 0 8 8 8 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ91022.1 - 2e-07 31.3 56.1 0.15 13.0 2.4 8.4 8 0 0 8 8 8 4 C2H2-type zinc finger ACBP PF00887.19 CDJ91022.1 - 9.1e-07 29.0 0.0 2.5e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Acyl CoA binding protein zf-C2H2_2 PF12756.7 CDJ91022.1 - 2.6e-05 24.5 34.7 0.0013 19.0 3.5 5.3 4 1 1 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CDJ91022.1 - 0.0067 16.8 37.7 0.025 15.0 0.1 7.8 8 0 0 8 8 8 3 Zinc-finger of C2H2 type zf-WRNIP1_ubi PF18279.1 CDJ91022.1 - 0.034 14.8 1.2 0.13 12.9 0.0 2.8 2 0 0 2 2 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-Di19 PF05605.12 CDJ91022.1 - 0.05 13.9 0.0 0.05 13.9 0.0 6.9 7 0 0 7 7 7 0 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_ZHX PF18387.1 CDJ91022.1 - 0.075 12.7 22.2 0.12 12.0 0.6 5.5 5 0 0 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 CDJ91022.1 - 0.13 12.7 0.0 0.13 12.7 0.0 7.8 7 2 2 9 9 9 0 Zinc-finger double domain Lyase_8_N PF08124.11 CDJ91022.1 - 0.14 11.0 2.1 0.18 10.7 1.0 1.6 2 0 0 2 2 2 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Actin_micro PF17003.5 CDJ91022.1 - 1.8 7.7 20.8 0.48 9.5 0.1 4.9 1 1 1 2 2 1 0 Putative actin-like family HypA PF01155.19 CDJ91022.1 - 9.2 6.3 10.8 7.4 6.6 1.6 3.9 3 2 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_jaz PF12171.8 CDJ91022.1 - 9.4 6.7 45.3 0.19 12.1 1.7 7.3 7 1 0 7 7 7 0 Zinc-finger double-stranded RNA-binding SH3_9 PF14604.6 CDJ91024.1 - 0.14 12.1 0.0 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 Variant SH3 domain DNA_pol_E_B PF04042.16 CDJ91025.1 - 5.1e-33 114.2 3.0 2.6e-22 79.2 0.2 2.5 1 1 1 2 2 2 2 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.8 CDJ91025.1 - 4.5e-17 62.1 2.0 8.9e-17 61.2 2.0 1.5 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal Lipase_GDSL_3 PF14606.6 CDJ91025.1 - 0.15 12.2 0.7 3.1 7.9 0.3 2.6 3 0 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase family HSNSD PF12062.8 CDJ91026.1 - 2.4e-152 508.1 0.4 3.4e-152 507.7 0.4 1.2 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.27 CDJ91026.1 - 1.4e-27 96.9 0.0 2.7e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase domain zf-U1 PF06220.12 CDJ91026.1 - 1.8e-22 78.8 4.0 4.8e-22 77.4 4.0 1.8 1 0 0 1 1 1 1 U1 zinc finger Sulfotransfer_3 PF13469.6 CDJ91026.1 - 3.4e-12 47.2 0.4 4.5e-06 27.2 0.0 2.9 1 1 1 2 2 2 2 Sulfotransferase family MFP2b PF12150.8 CDJ91027.1 - 1.1e-134 449.1 0.0 1.2e-134 448.9 0.0 1.0 1 0 0 1 1 1 1 Cytosolic motility protein DUF3421 PF11901.8 CDJ91027.1 - 0.068 13.2 0.7 10 6.2 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3421) DEAD PF00270.29 CDJ91029.1 - 2.4e-48 164.2 0.2 8.9e-48 162.4 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ91029.1 - 1.2e-30 106.1 0.0 3.2e-30 104.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ91029.1 - 0.00028 20.9 0.0 0.00093 19.2 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DTHCT PF08070.11 CDJ91029.1 - 6.4 7.6 11.4 13 6.5 3.1 2.5 2 0 0 2 2 2 0 DTHCT (NUC029) region DUF1759 PF03564.15 CDJ91030.1 - 1.5e-20 73.6 0.2 3.3e-20 72.5 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Asp_protease_2 PF13650.6 CDJ91030.1 - 0.00013 22.5 0.3 0.00085 19.9 0.2 2.3 1 1 1 2 2 2 1 Aspartyl protease Peptidase_A2B PF12384.8 CDJ91030.1 - 0.00082 19.0 0.2 0.0017 18.0 0.2 1.5 1 0 0 1 1 1 1 Ty3 transposon peptidase gag-asp_proteas PF13975.6 CDJ91030.1 - 0.00085 19.8 0.1 0.0024 18.4 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ91030.1 - 0.0012 18.6 0.1 0.0024 17.6 0.1 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.12 CDJ91030.1 - 0.0036 17.1 1.0 0.0071 16.1 0.0 1.9 2 0 0 2 2 2 1 Putative peptidase (DUF1758) eIF3g PF12353.8 CDJ91031.1 - 1.2 9.5 8.6 0.85 10.0 0.3 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Pkinase_Tyr PF07714.17 CDJ91032.1 - 4.1e-08 32.8 0.2 2e-07 30.6 0.2 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ91032.1 - 4.5e-06 26.2 0.1 0.0022 17.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain SH2 PF00017.24 CDJ91032.1 - 0.00015 21.8 0.0 0.00028 20.9 0.0 1.5 1 0 0 1 1 1 1 SH2 domain Transposase_1 PF01359.18 CDJ91034.1 - 6.1e-24 83.6 0.1 2.2e-23 81.9 0.1 1.9 2 0 0 2 2 2 1 Transposase (partial DDE domain) HTH_48 PF17906.1 CDJ91034.1 - 4e-14 52.4 0.0 1.8e-13 50.4 0.0 2.0 2 0 0 2 2 2 1 HTH domain in Mos1 transposase DDE_3 PF13358.6 CDJ91034.1 - 0.00013 21.8 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_AsnC-type PF13404.6 CDJ91034.1 - 0.00025 20.8 0.0 0.00051 19.8 0.0 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_32 PF13565.6 CDJ91034.1 - 0.00091 19.8 1.7 0.0023 18.5 0.1 2.6 2 1 1 3 3 3 1 Homeodomain-like domain HTH_24 PF13412.6 CDJ91034.1 - 0.0026 17.3 0.0 0.0047 16.5 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 CDJ91034.1 - 0.0062 16.3 0.6 0.13 12.1 0.1 2.9 3 0 0 3 3 3 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 CDJ91034.1 - 0.0067 16.6 0.1 0.046 14.0 0.0 2.2 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.6 CDJ91034.1 - 0.0076 16.3 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_11 PF08279.12 CDJ91034.1 - 0.011 15.7 0.0 0.037 14.0 0.0 1.9 2 0 0 2 2 2 0 HTH domain HTH_28 PF13518.6 CDJ91034.1 - 0.037 14.2 0.2 0.14 12.3 0.2 2.0 1 1 0 1 1 1 0 Helix-turn-helix domain PheRS_DBD1 PF18552.1 CDJ91034.1 - 0.096 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 PheRS DNA binding domain 1 HTH_Crp_2 PF13545.6 CDJ91034.1 - 0.16 12.0 0.1 0.5 10.4 0.1 1.9 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain DUF4484 PF14831.6 CDJ91035.1 - 0.012 15.6 0.5 0.012 15.6 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) HEAT_2 PF13646.6 CDJ91036.1 - 7e-10 39.2 14.3 0.0042 17.5 0.2 6.1 5 1 1 6 6 6 4 HEAT repeats HEAT_EZ PF13513.6 CDJ91036.1 - 3e-09 37.2 15.3 0.0063 17.0 0.0 8.9 9 2 2 11 11 9 2 HEAT-like repeat DUF3385 PF11865.8 CDJ91036.1 - 1.2e-06 28.5 5.4 5.5e-06 26.4 0.1 3.7 4 1 0 4 4 4 1 Domain of unknown function (DUF3385) UME PF08064.13 CDJ91036.1 - 3.8e-05 23.5 0.8 6.6 6.7 0.0 5.5 5 1 0 5 5 5 1 UME (NUC010) domain HEAT PF02985.22 CDJ91036.1 - 7.2e-05 22.7 8.2 0.34 11.3 0.0 6.9 7 0 0 7 7 6 2 HEAT repeat Adaptin_N PF01602.20 CDJ91036.1 - 0.00015 20.4 6.7 0.0099 14.5 1.6 3.6 2 1 2 4 4 4 4 Adaptin N terminal region Cnd1 PF12717.7 CDJ91036.1 - 0.0045 17.0 4.8 0.025 14.6 0.4 3.9 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 CDJ91036.1 - 0.0088 16.2 0.0 9.1 6.5 0.0 4.4 3 2 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 BLM10_mid PF16507.5 CDJ91036.1 - 0.026 13.2 0.5 0.12 11.0 0.0 2.2 3 0 0 3 3 3 0 Proteasome-substrate-size regulator, mid region Vac14_Fab1_bd PF12755.7 CDJ91036.1 - 0.048 14.3 0.6 41 4.8 0.0 4.6 4 1 1 5 5 5 0 Vacuolar 14 Fab1-binding region DUF5578 PF17741.1 CDJ91036.1 - 0.09 12.2 4.8 0.096 12.1 0.2 2.9 4 0 0 4 4 4 0 Family of unknown function (DUF5578) DUF4487 PF14868.6 CDJ91036.1 - 0.37 9.6 2.7 0.56 9.0 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4487) CTP_synth_N PF06418.14 CDJ91037.1 - 2.2e-115 384.5 0.0 3.1e-115 384.1 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 CDJ91037.1 - 2.7e-44 151.2 0.1 1e-35 123.2 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CDJ91037.1 - 5.1e-05 23.1 0.7 0.027 14.2 0.2 3.0 2 1 0 3 3 3 2 Peptidase C26 CbiA PF01656.23 CDJ91037.1 - 0.00067 19.7 0.0 0.0011 19.0 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 CDJ91037.1 - 0.018 14.2 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase MeaB PF03308.16 CDJ91037.1 - 0.076 12.0 0.1 0.15 11.0 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DJ-1_PfpI PF01965.24 CDJ91037.1 - 0.098 12.4 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family CGI-121 PF08617.10 CDJ91040.1 - 6.8e-35 120.6 0.2 8.8e-35 120.2 0.2 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Kelch_1 PF01344.25 CDJ91041.1 - 1.6e-59 197.3 15.3 1.9e-12 46.5 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CDJ91041.1 - 1.4e-44 149.0 4.8 1.9e-07 31.1 0.0 6.3 3 2 3 6 6 6 6 Kelch motif BACK PF07707.15 CDJ91041.1 - 9.1e-33 112.4 0.6 9.1e-33 112.4 0.6 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 CDJ91041.1 - 5.4e-28 97.4 0.0 8.8e-28 96.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 CDJ91041.1 - 5.5e-25 86.4 6.5 0.00034 20.5 0.3 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 CDJ91041.1 - 8e-20 70.6 0.9 8.8e-05 22.4 0.1 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ91041.1 - 1e-18 67.1 8.3 0.015 15.6 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ91041.1 - 4.4e-11 42.5 5.8 0.076 13.0 0.1 5.4 5 0 0 5 5 5 4 Kelch motif DUF2963 PF11178.8 CDJ91041.1 - 0.26 11.0 0.9 7.5 6.4 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2963) Methyltransf_11 PF08241.12 CDJ91042.1 - 1e-07 32.5 0.0 1.6e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ91042.1 - 1.1e-07 32.4 0.0 1.5e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 CDJ91042.1 - 1.2e-07 31.6 0.0 1.5e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 CDJ91042.1 - 9.7e-06 25.5 0.0 1.3e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ91042.1 - 2.1e-05 24.1 0.0 2.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 CDJ91042.1 - 0.0012 18.4 0.0 0.0014 18.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 CDJ91042.1 - 0.0022 18.7 0.0 0.0029 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ91042.1 - 0.0051 16.7 0.0 0.0074 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain WD40 PF00400.32 CDJ91043.1 - 7.9e-09 36.0 0.2 0.0022 18.8 0.0 4.0 3 1 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ91043.1 - 9.1e-05 22.7 0.0 0.17 12.2 0.0 2.8 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ91043.1 - 0.068 12.1 0.1 2.3 7.1 0.0 2.2 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 CDJ91043.1 - 0.14 10.9 0.2 0.34 9.6 0.2 1.6 1 1 1 2 2 2 0 Nup133 N terminal like Auto_anti-p27 PF06677.12 CDJ91044.1 - 6.5e-14 51.8 2.2 6.5e-14 51.8 2.2 2.0 2 0 0 2 2 2 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) BaffR-Tall_bind PF09256.10 CDJ91044.1 - 0.014 15.2 0.4 0.034 13.9 0.4 1.6 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding bZIP_1 PF00170.21 CDJ91046.1 - 2.2e-17 62.9 15.3 2.2e-17 62.9 15.3 1.9 2 1 0 2 2 2 1 bZIP transcription factor pKID PF02173.17 CDJ91046.1 - 4.3e-16 58.1 1.8 4.3e-16 58.1 1.8 1.7 2 0 0 2 2 2 1 pKID domain bZIP_2 PF07716.15 CDJ91046.1 - 1.2e-07 31.6 12.1 1.2e-07 31.6 12.1 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 CDJ91046.1 - 0.00065 20.2 4.8 0.00065 20.2 4.8 1.6 2 0 0 2 2 2 1 bZIP Maf transcription factor Adaptin_N PF01602.20 CDJ91047.1 - 2.1e-154 515.0 14.4 2.6e-154 514.6 14.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CDJ91047.1 - 7.5e-65 217.9 12.8 3e-63 212.7 2.1 4.0 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDJ91047.1 - 8.3e-21 74.2 4.0 2.3e-07 31.1 0.1 6.3 2 2 3 6 6 6 4 HEAT repeats HEAT PF02985.22 CDJ91047.1 - 9e-11 41.1 6.6 0.015 15.5 0.0 6.6 7 0 0 7 7 6 3 HEAT repeat Cnd3 PF12719.7 CDJ91047.1 - 1.1e-06 28.1 1.9 0.00042 19.6 0.0 3.5 2 2 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 CDJ91047.1 - 6.8e-06 25.8 3.7 0.079 12.5 0.1 4.3 2 2 1 3 3 3 2 CLASP N terminal Arm PF00514.23 CDJ91047.1 - 1.7e-05 24.7 0.9 0.44 10.7 0.0 4.6 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 CDJ91047.1 - 0.00024 21.2 4.6 1.4 9.2 0.0 4.9 1 1 2 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 TIP120 PF08623.10 CDJ91047.1 - 0.00069 19.4 8.1 3.9 7.2 0.0 4.7 3 1 0 4 4 4 3 TATA-binding protein interacting (TIP20) HEAT_EZ PF13513.6 CDJ91047.1 - 0.001 19.5 0.1 23 5.6 0.0 5.0 4 0 0 4 4 4 0 HEAT-like repeat Sec7_N PF12783.7 CDJ91047.1 - 0.0071 16.3 0.3 0.0071 16.3 0.3 3.2 2 1 2 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Phage_TAC_12 PF12363.8 CDJ91047.1 - 0.032 14.6 0.8 3.8 8.0 0.4 2.8 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC UNC45-central PF11701.8 CDJ91047.1 - 0.06 13.3 0.2 6 6.8 0.0 3.4 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central RasGEF_N_2 PF14663.6 CDJ91047.1 - 0.79 10.1 5.3 3.1 8.2 0.2 4.0 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain ShK PF01549.24 CDJ91050.1 - 0.015 15.8 3.0 0.024 15.2 3.0 1.4 1 0 0 1 1 1 0 ShK domain-like Csm1_N PF18504.1 CDJ91051.1 - 0.015 15.6 2.2 0.015 15.6 2.2 3.0 2 1 1 3 3 3 0 Csm1 N-terminal domain Ig_3 PF13927.6 CDJ91052.1 - 2e-06 28.3 0.0 3.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CDJ91052.1 - 1.4e-05 25.3 0.0 2.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CDJ91052.1 - 0.0039 17.3 0.1 0.0078 16.4 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain EGF_2 PF07974.13 CDJ91052.1 - 0.0048 17.2 12.5 0.0083 16.5 12.5 1.4 1 0 0 1 1 1 1 EGF-like domain Ig_5 PF16681.5 CDJ91052.1 - 0.032 14.6 0.2 0.082 13.3 0.1 1.7 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 CDJ91052.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 C17orf99 Ig domain I-set PF07679.16 CDJ91052.1 - 0.16 12.1 0.1 0.79 9.8 0.1 2.0 1 1 0 1 1 1 0 Immunoglobulin I-set domain Antig_Caf1 PF09255.10 CDJ91052.1 - 0.17 12.0 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Caf1 Capsule antigen V-set PF07686.17 CDJ91052.1 - 0.19 11.9 0.3 9.2 6.5 0.1 2.4 1 1 1 2 2 2 0 Immunoglobulin V-set domain Plasmod_Pvs28 PF06247.11 CDJ91052.1 - 1.1 9.6 5.1 3.3 8.1 5.1 1.9 1 0 0 1 1 1 0 Pvs28 EGF domain ABC_tran PF00005.27 CDJ91054.1 - 1.7e-24 86.9 0.0 3.1e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CDJ91054.1 - 3.3e-05 23.9 0.0 0.0033 17.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CDJ91054.1 - 0.016 15.1 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_19 PF13245.6 CDJ91054.1 - 0.018 15.3 0.1 0.15 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 CDJ91054.1 - 0.026 13.7 1.4 1.1 8.4 0.1 2.2 1 1 1 2 2 2 0 G-protein alpha subunit SMC_N PF02463.19 CDJ91054.1 - 0.045 13.2 0.2 0.38 10.2 0.2 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Na_Pi_cotrans PF02690.15 CDJ91054.1 - 0.071 13.2 6.5 0.18 11.9 6.5 1.7 1 0 0 1 1 1 0 Na+/Pi-cotransporter DUF4121 PF13497.6 CDJ91054.1 - 0.092 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) AAA_16 PF13191.6 CDJ91054.1 - 0.1 13.0 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 CDJ91054.1 - 0.17 12.4 0.1 0.58 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CDJ91054.1 - 0.19 11.4 0.0 0.4 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Glyco_transf_8 PF01501.20 CDJ91055.1 - 4.2e-12 46.2 1.5 5e-05 23.0 0.1 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 8 KN_motif PF12075.8 CDJ91055.1 - 1.6 8.6 5.1 9.3 6.1 0.3 3.3 2 1 0 2 2 2 0 KN motif Pkinase PF00069.25 CDJ91056.1 - 1.3e-10 41.1 0.0 2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ91056.1 - 0.00021 20.6 0.0 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ91056.1 - 0.00037 19.4 0.1 0.00043 19.2 0.1 1.3 1 1 0 1 1 1 1 Fungal protein kinase VWA_N PF08399.11 CDJ91057.1 - 2.4e-29 102.3 1.8 1.5e-28 99.8 0.3 2.6 2 0 0 2 2 2 1 VWA N-terminal VWA PF00092.28 CDJ91057.1 - 1.4e-14 54.7 0.0 3e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 CDJ91057.1 - 5e-11 42.8 0.0 1.2e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain dCache_1 PF02743.18 CDJ91057.1 - 5.2e-11 42.8 0.8 1.8e-10 41.0 0.0 2.2 2 1 0 2 2 2 1 Cache domain VWA_2 PF13519.6 CDJ91057.1 - 1.3e-10 41.9 0.0 4.5e-10 40.1 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain CobT_C PF11775.8 CDJ91057.1 - 0.089 12.4 0.0 0.72 9.5 0.0 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT VWA domain zf-C2H2_2 PF12756.7 CDJ91058.1 - 0.0012 19.1 1.5 0.0025 18.1 1.5 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CDJ91058.1 - 0.0076 16.6 3.9 0.0088 16.4 2.1 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type SF3a60_bindingd PF12108.8 CDJ91058.1 - 0.081 12.8 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain DUF4119 PF13494.6 CDJ91058.1 - 0.18 11.9 1.0 9.7 6.4 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) Collagen PF01391.18 CDJ91059.1 - 1.9e-11 43.5 140.3 4.8e-07 29.4 42.9 5.7 2 1 3 5 5 5 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ91059.1 - 2.1e-10 40.5 0.3 3e-10 40.0 0.3 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain GRP PF07172.11 CDJ91059.1 - 2.9e-05 24.7 11.9 2.9e-05 24.7 11.9 4.7 2 1 1 4 4 4 1 Glycine rich protein family Collagen PF01391.18 CDJ91060.1 - 2.2e-14 52.9 130.4 4e-08 32.9 42.7 5.1 2 1 2 4 4 4 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ91060.1 - 7.1e-11 42.0 0.2 1e-10 41.5 0.2 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Piwi PF02171.17 CDJ91061.1 - 1.3e-51 175.7 0.0 2.4e-51 174.8 0.0 1.5 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 CDJ91061.1 - 3.8e-15 55.9 0.1 8e-15 54.9 0.1 1.5 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 CDJ91061.1 - 0.00039 20.6 0.0 0.0015 18.7 0.0 2.1 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 CDJ91061.1 - 0.0039 17.5 0.0 0.0096 16.2 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoN PF16486.5 CDJ91061.1 - 0.031 14.9 0.0 0.072 13.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of argonaute A_deaminase PF00962.22 CDJ91062.1 - 2.7e-66 224.2 0.0 3.2e-66 223.9 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 CDJ91062.1 - 0.038 13.3 0.9 0.083 12.2 0.8 1.8 1 1 1 2 2 2 0 Amidohydrolase family eIF_4EBP PF05456.11 CDJ91062.1 - 0.1 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) MA3 PF02847.17 CDJ91063.1 - 1.2e-17 64.0 0.4 1.2e-17 64.0 0.4 2.9 3 1 0 3 3 3 1 MA3 domain MIF4G PF02854.19 CDJ91063.1 - 2.2e-12 47.1 2.3 4.6e-12 46.0 2.3 1.6 1 0 0 1 1 1 1 MIF4G domain BUD22 PF09073.10 CDJ91063.1 - 0.53 9.6 29.6 0.92 8.8 29.6 1.3 1 0 0 1 1 1 0 BUD22 TERF2_RBM PF16772.5 CDJ91063.1 - 8.1 6.0 7.4 16 5.0 0.0 3.2 3 0 0 3 3 3 0 Telomeric repeat-binding factor 2 Rap1-binding motif V-ATPase_G PF03179.15 CDJ91064.1 - 5.3e-11 43.0 9.8 5.3e-11 43.0 9.8 1.5 2 0 0 2 2 2 1 Vacuolar (H+)-ATPase G subunit TP53IP5 PF15331.6 CDJ91064.1 - 0.009 16.2 3.4 0.014 15.5 3.4 1.3 1 0 0 1 1 1 1 Cellular tumour antigen p53-inducible 5 Phage_cap_E PF03864.15 CDJ91064.1 - 0.048 12.8 4.8 2.8 7.0 3.1 2.0 2 0 0 2 2 2 0 Phage major capsid protein E MutS_III PF05192.18 CDJ91064.1 - 0.18 12.0 0.8 0.27 11.5 0.8 1.4 1 0 0 1 1 1 0 MutS domain III UPF0149 PF03695.13 CDJ91064.1 - 0.19 12.0 1.8 0.35 11.1 1.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) Tam41_Mmp37 PF09139.11 CDJ91065.1 - 3.6e-79 266.5 0.5 1.6e-47 162.6 0.1 2.0 1 1 1 2 2 2 2 Phosphatidate cytidylyltransferase, mitochondrial E3_UFM1_ligase PF09743.9 CDJ91065.1 - 0.023 14.3 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 E3 UFM1-protein ligase 1 Peptidase_C1 PF00112.23 CDJ91066.1 - 1.9e-47 162.2 10.1 2.5e-47 161.8 10.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ91066.1 - 0.5 9.1 3.6 0.63 8.8 1.4 1.9 2 0 0 2 2 2 0 Peptidase C1-like family Cadherin PF00028.17 CDJ91067.1 - 4.3e-136 443.8 18.3 6.6e-16 58.5 0.0 16.1 17 0 0 17 17 17 12 Cadherin domain Laminin_G_2 PF02210.24 CDJ91067.1 - 7.1e-22 78.3 0.0 3.8e-19 69.5 0.0 2.9 2 0 0 2 2 2 1 Laminin G domain Laminin_G_1 PF00054.23 CDJ91067.1 - 1.2e-18 67.6 0.0 2.8e-16 59.9 0.0 3.1 2 0 0 2 2 2 1 Laminin G domain Cadherin_C PF01049.17 CDJ91067.1 - 8.5e-12 45.6 0.0 1.9e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_3 PF16184.5 CDJ91067.1 - 3.5e-05 23.7 12.3 0.23 11.5 0.2 7.7 7 0 0 7 7 7 1 Cadherin-like Cadherin_2 PF08266.12 CDJ91067.1 - 4.7e-05 23.1 0.0 1.7 8.5 0.1 5.8 6 0 0 6 6 6 1 Cadherin-like PKD PF00801.20 CDJ91067.1 - 0.0053 16.6 2.2 24 4.9 0.3 5.1 4 0 0 4 4 4 0 PKD domain EGF PF00008.27 CDJ91067.1 - 0.016 15.5 23.8 0.42 10.9 1.5 3.8 3 0 0 3 3 3 0 EGF-like domain hEGF PF12661.7 CDJ91067.1 - 6.8 7.5 34.6 0.074 13.7 2.9 4.2 4 0 0 4 4 4 0 Human growth factor-like EGF CH PF00307.31 CDJ91068.1 - 1.1e-14 54.5 0.1 1.5e-14 54.1 0.1 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CDJ91068.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 CAMSAP CH domain DDE_3 PF13358.6 CDJ91071.1 - 3.2e-05 23.7 0.0 3.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DNA_pol_B_exo1 PF03104.19 CDJ91072.1 - 0.084 12.0 0.0 2.1 7.4 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase family B, exonuclease domain DUF3900 PF13039.6 CDJ91072.1 - 0.15 11.9 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3900) Collagen PF01391.18 CDJ91074.1 - 1.2e-24 85.8 103.2 5.5e-10 38.8 38.1 3.4 3 0 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ91074.1 - 7.3e-19 67.6 0.1 9.3e-19 67.2 0.1 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain COX14 PF14880.6 CDJ91074.1 - 0.043 13.7 2.2 0.074 12.9 2.2 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Asp PF00026.23 CDJ91075.1 - 3e-27 95.9 0.0 8.8e-16 58.2 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ91075.1 - 5e-05 23.6 0.0 0.00022 21.5 0.0 1.9 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal PP2C_2 PF13672.6 CDJ91076.1 - 1.2e-09 38.1 0.4 2.2e-09 37.3 0.4 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CDJ91076.1 - 0.012 15.5 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) SelP_N PF04592.14 CDJ91077.1 - 1.8e-07 30.8 1.2 1.8e-07 30.8 1.2 2.9 1 1 1 2 2 2 1 Selenoprotein P, N terminal region AhpC-TSA PF00578.21 CDJ91077.1 - 0.0088 16.0 0.2 0.025 14.5 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA family TFIIA PF03153.13 CDJ91077.1 - 0.022 14.8 22.1 0.027 14.5 22.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Redoxin PF08534.10 CDJ91077.1 - 0.037 13.7 0.1 0.09 12.5 0.1 1.7 1 1 0 1 1 1 0 Redoxin DUF853 PF05872.12 CDJ91077.1 - 1.7 7.1 4.2 2.4 6.6 4.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Hydin_ADK PF17213.3 CDJ91077.1 - 1.8 8.8 6.3 3.1 8.0 6.3 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF148 PF02520.17 CDJ91080.1 - 6.8e-07 29.4 0.2 9.3e-07 28.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF148 TRAP_alpha PF03896.16 CDJ91081.1 - 6e-46 156.9 0.1 6.5e-46 156.8 0.1 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF4064 PF13273.6 CDJ91081.1 - 0.013 15.7 0.0 0.019 15.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) S1FA PF04689.13 CDJ91081.1 - 0.031 14.4 0.0 0.06 13.5 0.0 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA RIFIN PF02009.16 CDJ91081.1 - 0.052 13.4 0.0 0.066 13.1 0.0 1.1 1 0 0 1 1 1 0 Rifin TMEM154 PF15102.6 CDJ91081.1 - 0.066 13.1 0.0 0.083 12.8 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family OAD_gamma PF04277.13 CDJ91081.1 - 1.9 9.2 4.1 16 6.2 4.1 2.1 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain NTF2 PF02136.20 CDJ91082.1 - 2.3e-17 63.6 0.0 2.7e-17 63.5 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 CDJ91082.1 - 0.016 15.2 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 Sec34 PF04136.15 CDJ91083.1 - 1.3e-37 129.0 1.9 1.6e-37 128.6 0.4 2.0 2 0 0 2 2 2 1 Sec34-like family FAM92 PF06730.11 CDJ91083.1 - 0.022 14.2 0.3 0.051 13.0 0.3 1.6 1 0 0 1 1 1 0 FAM92 protein DUF4461 PF14688.6 CDJ91083.1 - 0.046 13.5 0.0 1.2 8.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4461) Neur_chan_memb PF02932.16 CDJ91084.1 - 1.4e-09 38.4 0.0 1.5e-09 38.3 0.0 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region SCVP PF17619.2 CDJ91085.1 - 1e-22 80.8 0.2 1.3e-22 80.4 0.2 1.2 1 0 0 1 1 1 1 Secreted clade V proteins SCVP PF17619.2 CDJ91086.1 - 1.8e-43 147.3 2.2 2.1e-21 76.6 0.4 2.1 2 0 0 2 2 2 2 Secreted clade V proteins Guanylate_kin PF00625.21 CDJ91089.1 - 4.1e-27 95.0 0.0 4.8e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase SH3_1 PF00018.28 CDJ91090.1 - 1.2e-06 28.0 0.6 8.9e-06 25.2 0.9 2.3 2 1 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 CDJ91090.1 - 1.3e-06 28.0 0.0 3.1e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Variant SH3 domain Polysacc_deac_3 PF15421.6 CDJ91090.1 - 0.039 12.5 0.1 0.055 12.0 0.1 1.1 1 0 0 1 1 1 0 Putative polysaccharide deacetylase SH3_9 PF14604.6 CDJ91090.1 - 0.12 12.3 0.2 0.27 11.1 0.2 1.6 1 1 0 1 1 1 0 Variant SH3 domain L27 PF02828.16 CDJ91091.1 - 6.6e-06 25.8 0.9 1.2e-05 25.0 0.3 1.7 2 0 0 2 2 2 1 L27 domain Exo_endo_phos_2 PF14529.6 CDJ91092.1 - 0.039 13.8 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase RVT_1 PF00078.27 CDJ91093.1 - 5.7e-08 32.5 0.0 9.4e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Zot PF05707.12 CDJ91093.1 - 0.077 12.6 0.1 0.43 10.2 0.0 2.0 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Astacin PF01400.24 CDJ91096.1 - 5.9e-52 176.1 1.8 8.9e-52 175.5 1.8 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Astacin PF01400.24 CDJ91097.1 - 2.7e-45 154.4 0.1 3.5e-45 154.0 0.1 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) TcA_TcB_BD PF18276.1 CDJ91097.1 - 0.047 12.8 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 Tc toxin complex TcA C-terminal TcB-binding domain Peptidase_M10 PF00413.24 CDJ91097.1 - 0.076 12.9 1.7 9.4 6.1 0.6 2.3 1 1 0 2 2 2 0 Matrixin EGF PF00008.27 CDJ91098.1 - 1.9e-08 34.4 11.7 0.00044 20.5 1.1 2.7 2 1 0 2 2 2 2 EGF-like domain EGF_2 PF07974.13 CDJ91098.1 - 4.5e-07 30.1 16.1 6.3e-05 23.3 1.0 2.4 2 1 0 2 2 2 2 EGF-like domain hEGF PF12661.7 CDJ91098.1 - 6.4e-07 29.8 17.2 8e-05 23.1 2.4 3.5 4 0 0 4 4 4 2 Human growth factor-like EGF EGF_3 PF12947.7 CDJ91098.1 - 0.0018 18.5 12.2 0.011 15.9 4.0 2.7 2 1 0 2 2 2 2 EGF domain Laminin_EGF PF00053.24 CDJ91098.1 - 0.13 12.4 15.2 1.1 9.4 6.1 2.7 2 1 1 3 3 3 0 Laminin EGF domain EGF_CA PF07645.15 CDJ91098.1 - 0.17 12.1 16.6 0.25 11.6 6.9 2.4 2 0 0 2 2 2 0 Calcium-binding EGF domain Plasmod_Pvs28 PF06247.11 CDJ91098.1 - 0.69 10.3 16.4 2 8.8 2.3 2.3 2 0 0 2 2 2 0 Pvs28 EGF domain SLR1-BP PF07333.12 CDJ91098.1 - 7.6 7.1 15.5 8.7 6.9 3.4 2.5 2 0 0 2 2 2 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) Gal-bind_lectin PF00337.22 CDJ91099.1 - 4.4e-19 68.3 0.0 1.6e-13 50.4 0.0 2.1 1 1 1 2 2 2 2 Galactoside-binding lectin ABC_tran PF00005.27 CDJ91100.1 - 4.8e-09 36.8 0.0 6.3e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 CDJ91100.1 - 5.5e-05 23.1 0.0 7.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 CDJ91100.1 - 0.0011 18.6 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CDJ91100.1 - 0.0055 16.8 0.0 0.0083 16.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CDJ91100.1 - 0.0068 16.8 0.0 0.009 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDJ91100.1 - 0.0071 16.6 0.1 0.014 15.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 CDJ91100.1 - 0.0097 15.8 0.1 0.027 14.4 0.1 1.6 1 1 1 2 2 2 1 NTPase cobW PF02492.19 CDJ91100.1 - 0.013 15.0 0.1 0.021 14.4 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 CDJ91100.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CDJ91100.1 - 0.015 15.0 0.1 0.028 14.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 CDJ91100.1 - 0.021 14.1 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 CDJ91100.1 - 0.024 14.8 0.0 0.033 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 CDJ91100.1 - 0.025 14.7 0.4 0.043 13.9 0.4 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_28 PF13521.6 CDJ91100.1 - 0.027 14.7 0.0 0.035 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CDJ91100.1 - 0.034 14.7 0.0 0.052 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CDJ91100.1 - 0.068 13.7 0.0 0.095 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CDJ91100.1 - 0.087 12.5 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CDJ91100.1 - 0.098 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 CDJ91100.1 - 0.11 12.4 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.12 CDJ91100.1 - 0.14 12.1 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.15 CDJ91100.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Septin PF00735.18 CDJ91100.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.9 CDJ91100.1 - 0.21 11.3 0.1 0.39 10.4 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Adap_comp_sub PF00928.21 CDJ91101.1 - 6.2e-22 78.2 0.1 6.9e-22 78.1 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Cadherin PF00028.17 CDJ91102.1 - 3.1e-62 207.0 1.0 1.1e-11 45.0 0.0 8.8 9 0 0 9 9 9 7 Cadherin domain Cadherin_3 PF16184.5 CDJ91102.1 - 1.4e-11 44.3 6.9 0.027 14.5 0.0 6.2 6 2 0 6 6 6 4 Cadherin-like Cadherin_pro PF08758.11 CDJ91102.1 - 3.5e-05 23.9 0.0 0.0007 19.7 0.0 3.1 2 0 0 2 2 2 1 Cadherin prodomain like Cadherin_4 PF17803.1 CDJ91102.1 - 0.058 14.0 21.0 1.6 9.4 0.4 5.9 6 0 0 6 6 6 0 Bacterial cadherin-like domain Recep_L_domain PF01030.24 CDJ91103.1 - 2.5e-15 56.6 7.9 0.0012 19.0 0.0 5.9 6 0 0 6 6 6 4 Receptor L domain Radical_SAM PF04055.21 CDJ91103.1 - 0.09 13.1 0.6 0.38 11.1 0.6 2.1 1 0 0 1 1 1 0 Radical SAM superfamily Pkinase PF00069.25 CDJ91104.1 - 1.2e-64 218.2 0.0 1.4e-64 218.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ91104.1 - 6.5e-30 104.3 0.0 9.2e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ91104.1 - 0.00024 20.5 0.3 0.00038 19.9 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDJ91104.1 - 0.0092 15.3 0.3 0.049 12.9 0.1 1.9 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CDJ91104.1 - 0.012 14.6 0.2 0.044 12.7 0.2 1.7 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 CDJ91104.1 - 0.02 14.5 0.2 0.03 13.9 0.2 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 CDJ91104.1 - 0.062 13.2 0.1 0.17 11.8 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family HA2 PF04408.23 CDJ91105.1 - 8.9e-17 61.3 0.0 8.9e-17 61.3 0.0 2.7 3 1 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDJ91105.1 - 3.1e-08 33.9 0.0 8e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDJ91105.1 - 0.00016 21.9 0.4 0.00093 19.5 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain R3H PF01424.22 CDJ91106.1 - 7.9e-13 48.2 0.0 2.2e-12 46.8 0.0 1.9 1 0 0 1 1 1 1 R3H domain DEAD PF00270.29 CDJ91106.1 - 1.5e-09 37.8 0.1 5.1e-09 36.1 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CDJ91106.1 - 8.1e-05 23.0 0.3 0.00027 21.3 0.1 2.0 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 CDJ91106.1 - 0.00018 21.0 0.0 0.0004 19.8 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.6 CDJ91106.1 - 0.00036 20.8 0.1 0.0011 19.2 0.1 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CDJ91106.1 - 0.00038 19.6 0.0 0.0008 18.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.6 CDJ91106.1 - 0.0011 19.0 0.0 0.0066 16.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 CDJ91106.1 - 0.0084 16.1 1.0 1.7 8.6 0.3 3.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_7 PF12775.7 CDJ91106.1 - 0.01 15.4 0.0 0.033 13.7 0.0 1.9 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 CDJ91106.1 - 0.033 13.9 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CDJ91106.1 - 0.061 13.2 0.2 0.17 11.8 0.2 1.7 1 1 0 1 1 1 0 Rad17 P-loop domain NTPase_1 PF03266.15 CDJ91106.1 - 0.064 13.2 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 NTPase AAA_16 PF13191.6 CDJ91106.1 - 0.077 13.4 0.0 0.24 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 CDJ91106.1 - 0.1 13.1 0.0 0.45 11.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CDJ91106.1 - 0.15 11.3 0.7 0.28 10.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 CDJ91106.1 - 0.15 11.5 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein PhrC_PhrF PF11131.8 CDJ91107.1 - 1.4 8.6 5.5 4.5 6.9 5.5 1.9 1 0 0 1 1 1 0 Rap-phr extracellular signalling Cation_efflux PF01545.21 CDJ91108.1 - 4.9e-25 88.4 8.6 6.5e-25 88.0 8.6 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 CDJ91108.1 - 6.7e-11 42.2 0.9 1.8e-10 40.8 0.9 1.7 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF4837 PF16125.5 CDJ91108.1 - 0.33 9.9 1.1 2 7.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4837) EFF-AFF PF14884.6 CDJ91109.1 - 3.9e-225 748.5 10.1 4.3e-223 741.8 10.1 2.1 1 1 0 1 1 1 1 Type I membrane glycoproteins cell-cell fusogen Thiolase_N PF00108.23 CDJ91109.1 - 2e-22 79.8 0.0 1.5e-21 77.0 0.0 2.1 1 1 0 1 1 1 1 Thiolase, N-terminal domain SCP2 PF02036.17 CDJ91109.1 - 1.7e-15 57.4 0.2 3.2e-15 56.4 0.2 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family Thiolase_C PF02803.18 CDJ91109.1 - 4.9e-11 42.3 0.1 1.4e-10 40.9 0.1 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CDJ91109.1 - 7.6e-05 22.4 0.2 0.00015 21.4 0.2 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 CDJ91109.1 - 0.00038 19.3 0.0 0.00073 18.3 0.0 1.4 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) ACP_syn_III PF08545.10 CDJ91109.1 - 0.0013 18.6 0.2 0.0058 16.5 0.2 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Alkyl_sulf_C PF14864.6 CDJ91109.1 - 0.0043 17.3 0.2 0.029 14.6 0.1 2.2 2 0 0 2 2 2 1 Alkyl sulfatase C-terminal SCP2 PF02036.17 CDJ91110.1 - 1.2e-14 54.6 0.0 1.5e-14 54.3 0.0 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 CDJ91110.1 - 0.0027 18.0 0.0 0.046 14.0 0.0 1.9 1 1 1 2 2 2 1 Alkyl sulfatase C-terminal RabGAP-TBC PF00566.18 CDJ91111.1 - 1.9e-25 89.8 0.0 3.1e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Utp21 PF04192.12 CDJ91112.1 - 8.6e-52 175.9 2.8 1.4e-51 175.3 2.8 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 CDJ91112.1 - 1.7e-20 72.9 0.7 2.8e-06 27.9 0.1 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ91112.1 - 6.4e-16 58.4 1.3 0.025 14.9 0.0 7.1 4 3 4 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 CDJ91112.1 - 0.0018 17.3 0.4 0.028 13.4 0.1 2.7 2 1 1 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Utp12 PF04003.12 CDJ91112.1 - 0.0027 18.0 0.0 0.0073 16.6 0.0 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 CDJ91112.1 - 0.0044 16.0 0.1 0.086 11.8 0.0 2.6 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CDJ91112.1 - 0.0096 14.6 1.4 0.048 12.3 0.1 2.5 2 1 0 3 3 3 1 Nucleoporin Nup120/160 VID27 PF08553.10 CDJ91112.1 - 0.12 11.4 0.0 0.42 9.6 0.0 1.8 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain RabGAP-TBC PF00566.18 CDJ91114.1 - 1.9e-25 89.8 0.0 3.1e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Utp21 PF04192.12 CDJ91115.1 - 8.6e-52 175.9 2.8 1.4e-51 175.3 2.8 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 CDJ91115.1 - 1.7e-20 72.9 0.7 2.8e-06 27.9 0.1 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ91115.1 - 6.4e-16 58.4 1.3 0.025 14.9 0.0 7.1 4 3 4 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 CDJ91115.1 - 0.0018 17.3 0.4 0.028 13.4 0.1 2.7 2 1 1 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Utp12 PF04003.12 CDJ91115.1 - 0.0027 18.0 0.0 0.0073 16.6 0.0 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 CDJ91115.1 - 0.0044 16.0 0.1 0.086 11.8 0.0 2.6 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CDJ91115.1 - 0.0096 14.6 1.4 0.048 12.3 0.1 2.5 2 1 0 3 3 3 1 Nucleoporin Nup120/160 VID27 PF08553.10 CDJ91115.1 - 0.12 11.4 0.0 0.42 9.6 0.0 1.8 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain ABC_membrane PF00664.23 CDJ91117.1 - 2.8e-49 168.2 24.8 4.5e-31 108.5 13.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ91117.1 - 5.1e-39 133.9 0.1 1.9e-18 67.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CDJ91117.1 - 3.4e-08 33.6 0.5 0.018 14.9 0.0 3.3 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDJ91117.1 - 4.8e-08 32.7 1.0 0.00057 19.4 0.1 3.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CDJ91117.1 - 1.9e-06 27.9 0.2 0.0096 16.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 CDJ91117.1 - 6.1e-06 25.9 1.3 0.13 12.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 CDJ91117.1 - 7.8e-05 23.3 0.9 0.075 13.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 CDJ91117.1 - 0.0001 21.5 0.1 0.18 10.8 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Roc PF08477.13 CDJ91117.1 - 0.00085 19.5 0.4 18 5.6 0.0 5.0 5 0 0 5 5 5 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CDJ91117.1 - 0.0022 17.9 0.2 2.2 8.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CDJ91117.1 - 0.0038 17.6 0.9 2 8.8 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 CDJ91117.1 - 0.0042 16.4 0.4 0.92 8.8 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 CDJ91117.1 - 0.0059 16.9 2.1 1.5 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CDJ91117.1 - 0.0072 15.8 0.7 0.092 12.3 0.0 2.5 3 0 0 3 3 2 1 P-loop containing dynein motor region DUF87 PF01935.17 CDJ91117.1 - 0.011 15.9 3.5 0.011 15.8 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_33 PF13671.6 CDJ91117.1 - 0.028 14.6 0.1 1.4 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 CDJ91117.1 - 0.032 13.1 1.2 1.2 8.0 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 CDJ91117.1 - 0.069 12.9 0.6 1 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CDJ91117.1 - 0.08 12.9 2.2 7.6 6.6 0.2 3.1 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsK_SpoIIIE PF01580.18 CDJ91117.1 - 0.093 12.1 2.9 0.1 12.0 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 CDJ91117.1 - 0.2 11.2 1.5 0.62 9.6 0.4 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 CDJ91117.1 - 0.34 10.8 2.0 26 4.7 0.1 2.8 2 0 0 2 2 2 0 NTPase Dynamin_N PF00350.23 CDJ91117.1 - 0.4 10.7 5.0 6.4 6.8 0.3 2.4 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 CDJ91117.1 - 0.7 10.5 3.5 12 6.5 0.2 2.8 3 0 0 3 3 2 0 AAA domain SH2_2 PF14633.6 CDJ91118.1 - 2.4e-69 233.0 0.3 6.2e-69 231.7 0.1 1.8 2 0 0 2 2 2 1 SH2 domain HHH_7 PF14635.6 CDJ91118.1 - 3.4e-40 136.6 0.0 7.4e-40 135.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 CDJ91118.1 - 1e-22 80.5 0.0 1.9e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 S1 PF00575.23 CDJ91118.1 - 1.9e-07 31.3 0.0 5.7e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 S1 RNA binding domain HHH_9 PF17674.1 CDJ91118.1 - 6.2e-07 30.2 0.2 2.2e-06 28.4 0.2 2.1 1 0 0 1 1 1 1 HHH domain HHH_3 PF12836.7 CDJ91118.1 - 3.9e-06 27.0 0.0 9.4e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif SH2 PF00017.24 CDJ91118.1 - 4.8e-06 26.6 0.0 0.00014 21.9 0.0 2.7 2 0 0 2 2 2 1 SH2 domain Tex_YqgF PF16921.5 CDJ91118.1 - 0.11 13.0 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Tex protein YqgF-like domain ABC2_membrane PF01061.24 CDJ91119.1 - 2.8e-33 115.1 23.7 2.8e-33 115.1 23.7 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 CDJ91119.1 - 9.3e-25 87.7 0.0 2.9e-24 86.1 0.0 1.8 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 CDJ91119.1 - 0.00038 20.4 0.2 0.00089 19.2 0.1 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 CDJ91119.1 - 0.0046 16.6 0.0 0.0082 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 CDJ91119.1 - 0.012 14.9 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 CDJ91119.1 - 0.013 15.9 0.0 0.023 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ABC_ATPase PF09818.9 CDJ91119.1 - 0.014 14.2 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_28 PF13521.6 CDJ91119.1 - 0.025 14.8 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 CDJ91119.1 - 0.027 14.3 0.1 6.4 6.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CDJ91119.1 - 0.028 14.2 0.0 0.078 12.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CDJ91119.1 - 0.03 14.6 0.0 0.062 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CDJ91119.1 - 0.045 13.8 0.0 0.098 12.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase PDR_CDR PF06422.12 CDJ91119.1 - 0.083 12.8 1.8 1.9 8.5 0.0 3.0 2 0 0 2 2 2 0 CDR ABC transporter cobW PF02492.19 CDJ91119.1 - 0.086 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 CDJ91119.1 - 0.11 12.9 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF87 PF01935.17 CDJ91119.1 - 0.19 11.8 0.2 0.33 11.0 0.2 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain ABC2_membrane_3 PF12698.7 CDJ91119.1 - 1.9 7.5 21.7 3.7 6.6 21.7 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein SapB_2 PF03489.17 CDJ91120.1 - 0.0023 18.0 0.6 0.0052 16.9 0.1 1.8 2 0 0 2 2 2 1 Saposin-like type B, region 2 G-alpha PF00503.20 CDJ91121.1 - 1.9e-82 277.3 8.3 3e-82 276.6 8.3 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDJ91121.1 - 4.5e-14 52.3 1.0 4.3e-05 23.1 0.1 3.4 3 0 0 3 3 3 3 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ91121.1 - 0.00017 21.0 0.6 0.047 13.0 0.5 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CDJ91121.1 - 0.0015 18.1 0.3 4.4 6.8 0.0 3.2 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain Roc PF08477.13 CDJ91121.1 - 0.0098 16.1 0.3 1.1 9.5 0.0 2.6 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 CDJ91121.1 - 0.024 14.0 0.1 0.054 12.9 0.1 1.6 1 1 0 1 1 1 0 Bacterial TniB protein MMR_HSR1 PF01926.23 CDJ91121.1 - 0.027 14.6 0.0 6.3 6.9 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 CDJ91121.1 - 0.032 14.0 0.0 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 CDJ91121.1 - 0.06 12.7 0.3 0.89 8.8 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.6 CDJ91121.1 - 0.11 12.9 0.1 1.4 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Lactamase_B PF00753.27 CDJ91122.1 - 4.8e-14 52.8 6.6 1.3e-13 51.4 6.6 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CDJ91122.1 - 1e-06 28.4 1.1 1.7e-06 27.7 1.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CDJ91122.1 - 0.0013 18.7 0.2 0.0023 17.9 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain ECM11 PF15463.6 CDJ91122.1 - 0.016 15.8 5.2 1.5 9.4 0.3 2.4 1 1 1 2 2 2 0 Extracellular mutant protein 11 GDP_Man_Dehyd PF16363.5 CDJ91123.1 - 8.9e-71 239.0 0.0 1e-70 238.8 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CDJ91123.1 - 5.3e-56 189.8 0.0 6.7e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CDJ91123.1 - 2e-24 86.2 0.0 2e-23 83.0 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CDJ91123.1 - 3.1e-19 69.2 0.0 4.2e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 CDJ91123.1 - 3.5e-18 65.6 0.0 4.4e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CDJ91123.1 - 2.2e-14 53.3 0.3 1.1e-12 47.7 0.3 2.2 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 CDJ91123.1 - 0.0048 16.4 0.2 0.082 12.4 0.2 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDJ91123.1 - 0.13 12.2 0.0 0.39 10.6 0.0 1.7 1 1 0 1 1 1 0 KR domain PAP2_C PF14360.6 CDJ91124.1 - 2.5e-25 88.8 10.7 2.5e-25 88.8 10.7 2.4 3 0 0 3 3 3 1 PAP2 superfamily C-terminal SAM_1 PF00536.30 CDJ91124.1 - 3.6e-14 53.0 0.0 6.7e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CDJ91124.1 - 4.8e-06 26.6 0.0 9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 CDJ91124.1 - 0.0062 16.5 0.3 0.061 13.3 0.0 2.2 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 CDJ91124.1 - 0.037 13.9 0.1 0.069 13.0 0.1 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Collagen PF01391.18 CDJ91125.1 - 3e-12 46.1 69.8 3.2e-09 36.4 32.8 7.3 2 1 1 4 4 4 2 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ91125.1 - 3.9e-08 33.2 0.5 5.3e-08 32.8 0.5 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain 7tm_1 PF00001.21 CDJ91126.1 - 7.1e-15 55.0 19.0 7.1e-15 55.0 19.0 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) FNIP_C PF14638.6 CDJ91126.1 - 0.043 13.5 0.4 0.1 12.2 0.1 1.7 2 0 0 2 2 2 0 Folliculin-interacting protein C-terminus DUF4728 PF15860.5 CDJ91127.1 - 0.00062 20.4 5.1 0.0009 19.9 5.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4728) 7TM-7TMR_HD PF07698.11 CDJ91127.1 - 0.017 14.9 2.3 0.017 14.9 2.3 2.0 1 1 1 2 2 2 0 7TM receptor with intracellular HD hydrolase EVC2_like PF12297.8 CDJ91127.1 - 0.061 12.0 0.7 0.077 11.7 0.5 1.3 1 1 0 1 1 1 0 Ellis van Creveld protein 2 like protein DUF3810 PF12725.7 CDJ91127.1 - 0.81 9.0 6.0 0.82 9.0 5.6 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) DUF3290 PF11694.8 CDJ91127.1 - 2.2 8.2 9.1 1.4 8.9 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Med27 PF11571.8 CDJ91128.1 - 6e-17 61.8 1.0 1e-16 61.0 1.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 27 Med27 PF11571.8 CDJ91129.1 - 1e-16 61.1 1.0 2.7e-16 59.7 1.0 1.7 1 0 0 1 1 1 1 Mediator complex subunit 27 DUF2428 PF10350.9 CDJ91129.1 - 0.046 13.0 0.0 0.078 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) Hist_deacetyl PF00850.19 CDJ91130.1 - 3.8e-82 276.2 0.0 4.9e-82 275.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Prothymosin PF03247.14 CDJ91130.1 - 0.038 14.5 2.6 0.057 13.9 2.6 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family PPP4R2 PF09184.11 CDJ91132.1 - 7e-12 45.5 1.0 2.2e-11 43.9 0.9 1.7 1 1 0 1 1 1 1 PPP4R2 HEAT_EZ PF13513.6 CDJ91133.1 - 2.9e-20 72.3 2.9 6.4e-11 42.5 0.0 8.1 7 2 2 9 9 7 3 HEAT-like repeat Importin_rep_4 PF18808.1 CDJ91133.1 - 2.2e-18 66.3 1.5 1.6e-16 60.4 0.2 4.3 3 1 1 4 4 3 1 Importin repeat HEAT PF02985.22 CDJ91133.1 - 4.3e-18 63.9 3.7 0.00013 21.9 0.0 8.3 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 CDJ91133.1 - 7.5e-16 58.3 4.1 1.8e-06 28.3 0.0 7.7 8 1 1 9 9 9 2 HEAT repeats Vac14_Fab1_bd PF12755.7 CDJ91133.1 - 3e-10 40.6 6.4 0.0038 17.8 0.0 7.6 6 3 2 8 8 7 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 CDJ91133.1 - 4e-08 33.3 0.2 2 8.3 0.1 6.9 4 3 2 7 7 7 2 Domain of unknown function (DUF3385) Cnd1 PF12717.7 CDJ91133.1 - 5.6e-08 33.0 4.4 0.00048 20.2 0.0 4.3 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CDJ91133.1 - 1.1e-05 25.2 0.5 0.5 9.9 0.0 4.1 4 1 0 4 4 4 2 CLASP N terminal Arm PF00514.23 CDJ91133.1 - 3.3e-05 23.8 1.3 1.8 8.7 0.0 6.1 7 0 0 7 7 6 1 Armadillo/beta-catenin-like repeat Importin_rep_5 PF18816.1 CDJ91133.1 - 0.0003 21.0 0.8 0.0062 16.8 0.0 3.2 3 0 0 3 3 2 1 Importin repeat Adaptin_N PF01602.20 CDJ91133.1 - 0.0062 15.1 9.2 0.0098 14.5 0.0 3.4 5 0 0 5 5 5 2 Adaptin N terminal region Importin_rep_6 PF18829.1 CDJ91133.1 - 0.0091 16.1 0.6 0.05 13.7 0.4 2.5 2 0 0 2 2 1 1 Importin repeat 6 MMS19_C PF12460.8 CDJ91133.1 - 0.013 14.6 5.4 0.075 12.1 0.4 3.7 3 1 1 4 4 4 0 RNAPII transcription regulator C-terminal DUF4042 PF13251.6 CDJ91133.1 - 0.014 15.1 0.1 40 3.8 0.2 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) HEAT_PBS PF03130.16 CDJ91133.1 - 0.016 15.8 2.6 56 4.8 0.0 5.9 6 0 0 6 6 4 0 PBS lyase HEAT-like repeat RasGEF_N_2 PF14663.6 CDJ91133.1 - 0.026 14.9 0.3 1 9.8 0.1 3.7 3 1 1 4 4 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain NifQ PF04891.12 CDJ91133.1 - 0.059 13.7 5.9 3.2 8.1 0.6 2.8 2 0 0 2 2 2 0 NifQ DUF2063 PF09836.9 CDJ91133.1 - 0.079 13.2 0.0 8.3 6.7 0.0 3.2 2 0 0 2 2 2 0 Putative DNA-binding domain DUF1682 PF07946.14 CDJ91133.1 - 0.65 9.1 5.9 2.8 7.0 3.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1682) Troponin PF00992.20 CDJ91133.1 - 1 9.7 6.6 2.2 8.6 6.6 1.4 1 0 0 1 1 1 0 Troponin Kelch_1 PF01344.25 CDJ91134.1 - 2.1e-51 171.3 25.7 2.5e-11 43.0 0.0 7.8 7 1 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 CDJ91134.1 - 6.8e-38 127.7 4.1 8.9e-08 32.2 0.1 7.2 3 2 4 7 7 7 6 Kelch motif BACK PF07707.15 CDJ91134.1 - 4.3e-28 97.4 0.6 4.3e-28 97.4 0.6 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 CDJ91134.1 - 2e-23 82.7 2.4 1.2e-22 80.3 2.4 2.1 1 1 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 CDJ91134.1 - 9.8e-19 66.5 7.6 0.016 15.2 0.3 6.7 5 2 1 6 6 6 5 Kelch motif Kelch_4 PF13418.6 CDJ91134.1 - 1.9e-10 40.6 9.2 1.2 9.2 0.0 6.9 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ91134.1 - 6.2e-10 38.9 0.2 0.11 12.5 0.0 5.9 6 0 0 6 6 6 2 Kelch motif Kelch_3 PF13415.6 CDJ91134.1 - 1.2e-07 31.9 0.3 0.29 11.5 0.0 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain EF-hand_7 PF13499.6 CDJ91135.1 - 3.6e-23 81.8 5.3 3.1e-17 62.8 0.8 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CDJ91135.1 - 7.3e-22 75.2 7.8 5.8e-07 28.6 0.2 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CDJ91135.1 - 7.4e-19 66.0 7.6 2e-05 24.1 0.2 4.6 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 CDJ91135.1 - 1.5e-14 52.7 5.1 0.00034 20.0 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 CDJ91135.1 - 7.3e-14 51.4 3.0 0.00011 22.0 0.0 3.3 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ91135.1 - 0.00011 22.5 3.3 0.025 14.9 0.6 3.3 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CDJ91135.1 - 0.00046 20.1 4.4 0.81 9.7 0.1 3.4 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CDJ91135.1 - 0.0026 18.0 0.1 0.83 10.0 0.0 2.9 2 2 1 3 3 3 1 EF-hand domain Caleosin PF05042.13 CDJ91135.1 - 0.011 15.6 2.5 1.2 9.0 2.5 3.2 1 1 0 1 1 1 0 Caleosin related protein S10_plectin PF03501.15 CDJ91135.1 - 0.11 12.6 0.1 0.29 11.2 0.0 1.8 2 1 0 2 2 2 0 Plectin/S10 domain Glyco_hydro_18 PF00704.28 CDJ91136.1 - 6e-09 36.1 0.0 7.3e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Adap_comp_sub PF00928.21 CDJ91138.1 - 2e-73 247.0 0.0 2.4e-73 246.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CDJ91138.1 - 1.1e-06 28.7 0.4 2.3e-06 27.6 0.4 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Longin PF13774.6 CDJ91138.1 - 0.13 12.4 0.3 0.27 11.3 0.3 1.5 1 0 0 1 1 1 0 Regulated-SNARE-like domain BAF PF02961.14 CDJ91139.1 - 2.8e-36 123.8 0.0 4.7e-36 123.1 0.0 1.3 1 0 0 1 1 1 1 Barrier to autointegration factor L51_S25_CI-B8 PF05047.16 CDJ91139.1 - 2.6e-14 52.9 0.0 4.8e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RSD-2 PF07547.13 CDJ91140.1 - 4.6e-07 30.2 0.0 0.0067 16.9 0.0 3.0 2 0 0 2 2 2 2 RSD-2 N-terminal domain Peptidase_C92 PF05708.12 CDJ91140.1 - 0.071 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family CtaG_Cox11 PF04442.14 CDJ91140.1 - 0.12 12.4 1.1 3.7 7.6 0.1 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein CtaG/Cox11 ERG4_ERG24 PF01222.17 CDJ91141.1 - 9e-34 117.0 11.0 1.1e-33 116.7 11.0 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 CDJ91141.1 - 7.8e-06 25.6 0.3 1.1e-05 25.1 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Peptidase_M50B PF13398.6 CDJ91141.1 - 0.016 14.8 2.1 0.78 9.3 0.5 2.3 2 0 0 2 2 2 0 Peptidase M50B-like ICMT PF04140.14 CDJ91141.1 - 0.1 13.1 0.0 0.1 13.1 0.0 2.5 3 1 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Peptidase_S49_N PF08496.10 CDJ91142.1 - 0.036 14.1 0.7 0.036 14.1 0.7 1.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF1077 PF06417.12 CDJ91142.1 - 0.13 12.3 0.8 0.17 11.9 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1077) IHO1 PF15771.5 CDJ91142.1 - 0.7 8.6 7.3 0.82 8.4 7.3 1.0 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 CYYR1 PF10873.8 CDJ91142.1 - 0.86 10.0 4.7 3.7 8.0 4.7 1.8 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 LapA_dom PF06305.11 CDJ91142.1 - 8.5 6.3 8.3 1.4 8.8 0.9 2.4 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain Ribosomal_L2_C PF03947.18 CDJ91143.1 - 7.6e-45 152.2 5.5 1.3e-44 151.4 5.5 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CDJ91143.1 - 1.8e-15 56.6 0.3 7.5e-15 54.7 0.1 2.1 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain DUF3093 PF11292.8 CDJ91143.1 - 0.14 12.4 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) zf-C2H2_4 PF13894.6 CDJ91145.1 - 8.7e-07 29.3 26.6 0.032 15.0 0.5 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-Di19 PF05605.12 CDJ91145.1 - 3.8e-06 27.1 12.7 3.4e-05 24.0 4.5 3.2 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 CDJ91145.1 - 7.4e-05 22.4 1.3 7.4e-05 22.4 1.3 4.3 5 0 0 5 5 5 1 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 CDJ91145.1 - 0.00017 21.8 19.2 0.028 14.9 0.1 4.8 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 CDJ91145.1 - 0.00019 21.7 25.8 0.036 14.5 0.8 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-met PF12874.7 CDJ91145.1 - 0.0012 19.2 11.0 0.0047 17.3 0.8 3.6 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDJ91145.1 - 0.012 15.9 10.0 0.94 9.8 0.1 3.7 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF629 PF04780.12 CDJ91145.1 - 0.044 12.3 4.5 0.24 9.9 0.5 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.7 CDJ91145.1 - 0.19 12.1 0.1 0.19 12.1 0.1 3.6 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 CDJ91145.1 - 1.9 8.2 9.8 0.34 10.6 0.4 2.8 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_11 PF16622.5 CDJ91145.1 - 2.1 8.2 6.1 2.4 8.0 0.7 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type DUF4379 PF14311.6 CDJ91145.1 - 2.2 8.7 7.7 12 6.4 0.9 2.7 2 1 0 2 2 2 0 Probable Zinc-ribbon domain Zn_ribbon_SprT PF17283.2 CDJ91145.1 - 4 7.4 9.7 15 5.6 3.8 2.6 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Pkinase PF00069.25 CDJ91146.1 - 2.3e-59 200.9 0.2 2.8e-59 200.6 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ91146.1 - 6.6e-37 127.2 0.1 9.4e-37 126.7 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ91146.1 - 5.4e-08 32.5 0.0 9.4e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CDJ91146.1 - 9.8e-05 21.3 0.0 0.0002 20.3 0.0 1.6 1 1 0 1 1 1 1 Fungal protein kinase Peptidase_S32 PF05579.13 CDJ91146.1 - 0.03 13.5 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 DUF1279 PF06916.13 CDJ91147.1 - 0.043 14.4 0.0 0.064 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) HEAT PF02985.22 CDJ91148.1 - 5.1e-10 38.7 2.2 0.0033 17.5 0.0 4.0 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 CDJ91148.1 - 8.7e-06 26.1 0.4 0.037 14.5 0.1 3.3 2 1 1 3 3 3 2 HEAT-like repeat Cnd1 PF12717.7 CDJ91148.1 - 5e-05 23.4 0.9 0.03 14.4 0.2 2.7 1 1 1 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDJ91148.1 - 0.00011 22.5 0.4 0.41 11.1 0.0 3.1 1 1 1 3 3 3 3 HEAT repeats ERAP1_C PF11838.8 CDJ91148.1 - 0.032 13.8 0.0 0.04 13.5 0.0 1.1 1 0 0 1 1 1 0 ERAP1-like C-terminal domain UME PF08064.13 CDJ91148.1 - 0.14 12.1 0.1 1.3 9.0 0.1 2.4 1 1 0 1 1 1 0 UME (NUC010) domain HEAT PF02985.22 CDJ91151.1 - 8.8e-09 34.9 15.2 0.034 14.4 0.0 8.7 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.6 CDJ91151.1 - 5.1e-06 26.8 4.8 12 6.4 0.1 6.8 8 0 0 8 8 8 2 HEAT repeats Cnd1 PF12717.7 CDJ91151.1 - 0.00017 21.7 9.5 2.1 8.4 0.2 6.1 5 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CDJ91151.1 - 0.04 14.4 15.2 1.4 9.5 0.1 7.6 8 1 0 8 8 8 0 HEAT-like repeat DUF1722 PF08349.11 CDJ91151.1 - 0.13 12.5 0.1 4.4 7.6 0.0 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF2441 PF10386.9 CDJ91151.1 - 0.19 11.7 0.0 0.59 10.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2441) DUF3385 PF11865.8 CDJ91151.1 - 0.31 10.9 3.6 1.9 8.4 0.1 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF3385) CAP PF00188.26 CDJ91152.1 - 6.7e-30 104.5 2.7 3.9e-19 69.7 0.6 2.5 2 0 0 2 2 2 2 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ91152.1 - 6.9e-06 26.3 0.1 0.0072 16.6 0.0 3.7 4 0 0 4 4 4 2 Ancylostoma-associated secreted protein related BCA_ABC_TP_C PF12399.8 CDJ91152.1 - 6.9e-05 22.7 33.9 32 4.6 0.1 9.3 9 0 0 9 9 9 9 Branched-chain amino acid ATP-binding cassette transporter NinE PF05322.11 CDJ91152.1 - 0.032 14.1 0.0 14 5.6 0.0 2.7 2 0 0 2 2 2 0 NINE Protein Amb_V_allergen PF03913.13 CDJ91152.1 - 2.2 8.3 5.2 6.3 6.8 4.3 2.2 1 1 1 2 2 2 0 Amb V Allergen Methyltransf_11 PF08241.12 CDJ91153.1 - 1.5e-08 35.2 0.0 2.6e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ91153.1 - 4.1e-06 26.7 0.0 6.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ91153.1 - 1.2e-05 25.9 0.0 4.9e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ91153.1 - 0.0038 17.9 0.0 0.0071 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RRM_1 PF00076.22 CDJ91154.1 - 2.8e-16 59.1 0.0 4.7e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3987 PF13148.6 CDJ91154.1 - 0.091 11.8 0.1 0.12 11.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) NUP50 PF08911.11 CDJ91154.1 - 0.13 13.0 0.7 1.4 9.6 0.1 2.3 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) YL1 PF05764.13 CDJ91155.1 - 2.6e-22 80.1 36.9 8e-16 58.9 7.6 3.0 2 1 1 3 3 3 2 YL1 nuclear protein YL1_C PF08265.11 CDJ91155.1 - 5.1e-13 48.5 0.3 8.7e-13 47.8 0.3 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF1899 PF08953.11 CDJ91156.1 - 4.5e-11 42.5 0.2 1.9e-10 40.4 0.2 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 CDJ91156.1 - 8.4e-05 23.3 2.2 8.4e-05 23.3 2.2 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ91156.1 - 0.028 14.7 0.1 0.044 14.1 0.1 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ91156.1 - 0.054 12.4 0.0 0.06 12.3 0.0 1.0 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RRM_1 PF00076.22 CDJ91157.1 - 1.7e-25 88.7 0.0 6e-12 45.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 CDJ91157.1 - 0.0088 16.3 0.1 1.3 9.3 0.0 3.0 2 1 1 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter RRM_occluded PF16842.5 CDJ91157.1 - 0.012 15.4 0.0 0.038 13.9 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_7 PF16367.5 CDJ91157.1 - 0.052 13.7 0.0 4.5 7.5 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif Mur_ligase_M PF08245.12 CDJ91158.1 - 0.073 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Mur ligase middle domain Mur_ligase_C PF02875.21 CDJ91159.1 - 0.00089 19.5 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain TBP-binding PF09247.11 CDJ91160.1 - 0.062 13.6 0.1 0.087 13.1 0.1 1.2 1 0 0 1 1 1 0 TATA box-binding protein binding Peptidase_A17 PF05380.13 CDJ91164.1 - 3e-42 144.4 1.3 4.7e-42 143.8 1.3 1.3 1 0 0 1 1 1 1 Pao retrotransposon peptidase RVT_1 PF00078.27 CDJ91164.1 - 6.2e-08 32.4 0.1 1.8e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Kinesin_assoc PF16183.5 CDJ91164.1 - 0.037 14.2 0.1 0.11 12.7 0.1 1.7 1 0 0 1 1 1 0 Kinesin-associated RT_RNaseH_2 PF17919.1 CDJ91164.1 - 0.038 14.0 0.2 0.099 12.7 0.2 1.7 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ91164.1 - 0.37 11.1 1.8 0.36 11.1 0.3 1.8 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Peptidase_A17 PF05380.13 CDJ91165.1 - 1.6e-09 37.9 0.6 3e-09 37.1 0.6 1.4 1 0 0 1 1 1 1 Pao retrotransposon peptidase SOG2 PF10428.9 CDJ91165.1 - 0.076 12.2 1.5 0.077 12.2 0.2 1.7 2 0 0 2 2 2 0 RAM signalling pathway protein DUF1758 PF05585.12 CDJ91166.1 - 4.7e-13 49.2 0.3 2.3e-12 47.0 0.0 2.2 2 0 0 2 2 2 1 Putative peptidase (DUF1758) RVT_1 PF00078.27 CDJ91166.1 - 4.3e-07 29.7 0.0 9.8e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CDJ91166.1 - 3.6e-05 24.3 0.0 8.4e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ91166.1 - 0.00021 21.8 0.0 0.00056 20.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 CDJ91166.1 - 0.0029 17.6 20.7 0.018 15.1 0.6 3.5 3 0 0 3 3 3 2 Zinc knuckle RVP_2 PF08284.11 CDJ91166.1 - 0.01 15.6 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Kinesin_assoc PF16183.5 CDJ91166.1 - 0.047 13.8 0.4 0.78 9.9 0.1 2.8 2 1 0 2 2 2 0 Kinesin-associated zf-CCHC_2 PF13696.6 CDJ91166.1 - 0.13 12.1 14.1 0.07 13.0 5.4 2.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ91166.1 - 4.2 7.4 9.3 4.7 7.3 5.3 2.7 1 1 1 2 2 2 0 Zinc knuckle Shugoshin_C PF07557.11 CDJ91167.1 - 2.2e-05 24.2 0.4 3.8e-05 23.4 0.4 1.4 1 0 0 1 1 1 1 Shugoshin C terminus DUF4191 PF13829.6 CDJ91167.1 - 0.32 10.3 1.9 0.53 9.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) MH1 PF03165.16 CDJ91168.1 - 8.5e-14 51.6 9.1 1.1e-08 35.1 1.3 2.4 1 1 1 2 2 2 2 MH1 domain RhoGAP PF00620.27 CDJ91168.1 - 0.069 13.0 0.1 0.097 12.5 0.1 1.2 1 0 0 1 1 1 0 RhoGAP domain Lactamase_B_6 PF16661.5 CDJ91172.1 - 3.5e-11 42.9 0.0 4.5e-09 36.0 0.0 2.6 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 CDJ91172.1 - 1.6e-07 31.6 0.0 4.2e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Beta_lactamase3 PF17030.5 CDJ91172.1 - 0.0083 15.4 0.1 0.029 13.6 0.1 2.0 2 1 0 2 2 2 1 Putative beta-lactamase-like family V-set PF07686.17 CDJ91174.1 - 0.025 14.7 1.6 0.22 11.7 0.1 2.9 2 2 0 2 2 2 0 Immunoglobulin V-set domain C2-set PF05790.15 CDJ91174.1 - 0.063 13.5 0.0 0.22 11.7 0.0 1.9 1 0 0 1 1 1 0 Immunoglobulin C2-set domain WD40 PF00400.32 CDJ91176.1 - 8.8e-07 29.5 2.1 0.78 10.7 0.0 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat LAMTOR5 PF16672.5 CDJ91177.1 - 1.4e-16 60.2 0.1 2.1e-16 59.6 0.1 1.2 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 DUF2173 PF09941.9 CDJ91177.1 - 0.011 16.1 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2173) PCAF_N PF06466.11 CDJ91178.1 - 0.00047 19.8 0.1 0.00058 19.5 0.1 1.1 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain SR1P PF13790.6 CDJ91178.1 - 0.012 15.8 0.5 4.4 7.5 0.1 2.3 2 0 0 2 2 2 0 SR1 protein Bromodomain PF00439.25 CDJ91179.1 - 3.2e-17 62.4 0.0 9.4e-17 60.9 0.0 1.8 1 0 0 1 1 1 1 Bromodomain PCAF_N PF06466.11 CDJ91179.1 - 1.2e-13 51.2 0.6 2e-13 50.5 0.6 1.3 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain Acetyltransf_1 PF00583.25 CDJ91179.1 - 1.1e-06 28.8 0.0 2.1e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDJ91179.1 - 0.00034 20.5 0.0 0.00067 19.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDJ91179.1 - 0.0007 20.0 0.2 0.0017 18.8 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HLH PF00010.26 CDJ91180.1 - 3.9e-09 36.3 0.2 1.4e-06 28.1 0.0 2.5 2 0 0 2 2 2 2 Helix-loop-helix DNA-binding domain DivIC PF04977.15 CDJ91180.1 - 0.13 12.0 0.1 0.5 10.2 0.1 1.9 2 0 0 2 2 2 0 Septum formation initiator DUF2673 PF10880.8 CDJ91180.1 - 0.66 10.1 3.4 7.7 6.7 3.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) MerR-DNA-bind PF09278.11 CDJ91180.1 - 0.89 10.1 2.8 2.6 8.6 0.5 2.6 2 0 0 2 2 2 0 MerR, DNA binding CIAPIN1 PF05093.13 CDJ91181.1 - 2.8e-22 79.1 16.8 1.9e-16 60.4 2.7 2.6 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF1115 PF06544.12 CDJ91181.1 - 3e-11 43.6 0.0 7.1e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RWD PF05773.22 CDJ91181.1 - 1.7e-06 28.3 0.0 4.2e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 RWD domain DUF2190 PF09956.9 CDJ91181.1 - 0.015 15.8 0.7 0.026 15.0 0.7 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2190) Nup54_C PF18437.1 CDJ91181.1 - 0.15 12.0 0.4 0.75 9.7 0.0 2.0 2 0 0 2 2 2 0 Nup54 C-terminal interacting domain CD36 PF01130.21 CDJ91182.1 - 3.7e-107 358.8 0.1 4.3e-107 358.5 0.1 1.0 1 0 0 1 1 1 1 CD36 family POB3_N PF17292.2 CDJ91183.1 - 1.5e-26 92.6 1.0 6.1e-23 81.1 0.3 2.5 2 0 0 2 2 2 2 POB3-like N-terminal PH domain Rtt106 PF08512.12 CDJ91183.1 - 3.8e-25 88.1 0.1 5.1e-24 84.5 0.0 2.7 2 1 0 2 2 2 1 Histone chaperone Rttp106-like SSrecog PF03531.14 CDJ91183.1 - 3.5e-22 78.1 0.0 1.6e-21 75.9 0.0 2.3 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) HMG_box PF00505.19 CDJ91183.1 - 7.6e-17 61.5 7.4 7.6e-17 61.5 7.4 2.5 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ91183.1 - 4e-11 43.3 8.3 4e-11 43.3 8.3 2.4 2 0 0 2 2 2 1 HMG-box domain HMG_box_5 PF14887.6 CDJ91183.1 - 4.2e-05 23.4 7.8 0.00013 21.8 7.8 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box 5 WD40 PF00400.32 CDJ91184.1 - 2.1e-21 75.8 39.1 0.0023 18.7 0.4 10.7 13 0 0 13 13 13 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ91184.1 - 5.7e-12 45.8 7.0 0.37 11.1 0.0 7.6 6 1 1 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 CDJ91184.1 - 0.065 11.2 0.2 0.18 9.8 0.2 1.7 1 0 0 1 1 1 0 IKI3 family Ribosomal_S28e PF01200.18 CDJ91185.1 - 3.2e-34 116.7 1.0 3.5e-34 116.6 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e DUF19 PF01579.18 CDJ91186.1 - 2.4e-05 24.2 1.5 4.5e-05 23.3 1.5 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF19) DUF1397 PF07165.11 CDJ91186.1 - 9.9e-05 21.8 4.4 0.065 12.6 0.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1397) CPG4 PF15481.6 CDJ91186.1 - 0.00067 20.2 6.7 0.0022 18.6 1.8 2.8 2 1 1 3 3 3 1 Chondroitin proteoglycan 4 RGM_N PF06535.12 CDJ91186.1 - 0.13 12.5 2.4 2.7 8.2 0.2 2.3 2 0 0 2 2 2 0 Repulsive guidance molecule (RGM) N-terminus BolA PF01722.18 CDJ91187.1 - 2.2e-13 50.3 0.0 6.1e-13 48.8 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein RRM_1 PF00076.22 CDJ91188.1 - 2.5e-10 40.0 0.1 7.3e-10 38.5 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_9 PF18444.1 CDJ91188.1 - 5.3e-05 23.0 0.0 8.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif Tmemb_40 PF10160.9 CDJ91189.1 - 1.6e-69 234.2 16.1 2e-69 233.9 16.1 1.0 1 0 0 1 1 1 1 Predicted membrane protein DUF3740 PF12548.8 CDJ91190.1 - 0.043 14.3 0.1 0.069 13.6 0.1 1.4 1 0 0 1 1 1 0 Sulfatase protein MULE PF10551.9 CDJ91191.1 - 0.06 13.8 0.0 0.12 12.8 0.0 1.6 1 1 0 1 1 1 0 MULE transposase domain PBP PF01161.20 CDJ91193.1 - 0.0052 17.1 0.0 0.0077 16.5 0.0 1.3 1 1 0 1 1 1 1 Phosphatidylethanolamine-binding protein Apyrase PF06079.11 CDJ91194.1 - 4e-61 206.8 0.6 4.1e-34 118.1 0.1 2.0 1 1 1 2 2 2 2 Apyrase Trehalose_PPase PF02358.16 CDJ91194.1 - 0.03 13.4 0.0 0.039 13.1 0.0 1.1 1 0 0 1 1 1 0 Trehalose-phosphatase GIY-YIG PF01541.24 CDJ91194.1 - 0.067 13.5 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 GIY-YIG catalytic domain Apyrase PF06079.11 CDJ91195.1 - 1.3e-48 165.7 0.0 1.4e-48 165.6 0.0 1.0 1 0 0 1 1 1 1 Apyrase HTH_26 PF13443.6 CDJ91197.1 - 0.0004 20.8 0.1 0.0013 19.1 0.1 1.8 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain HTH_IclR PF09339.10 CDJ91197.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain MarR_2 PF12802.7 CDJ91197.1 - 0.035 14.0 0.1 0.082 12.8 0.1 1.6 1 0 0 1 1 1 0 MarR family CENP-B_N PF04218.13 CDJ91197.1 - 0.042 13.5 0.1 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain LacI PF00356.21 CDJ91197.1 - 0.055 13.3 0.3 0.57 10.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_Tnp_ISL3 PF13542.6 CDJ91197.1 - 0.057 12.8 0.1 0.16 11.4 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.6 CDJ91197.1 - 0.08 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 CDJ91197.1 - 0.33 10.8 2.9 8.4 6.3 0.1 3.2 3 0 0 3 3 3 0 Homeodomain-like domain HTH_32 PF13565.6 CDJ91197.1 - 1.7 9.3 7.3 2.5 8.8 0.3 2.8 3 0 0 3 3 3 0 Homeodomain-like domain EamA PF00892.20 CDJ91199.1 - 3.5e-06 27.2 14.1 3.5e-06 27.2 14.1 2.5 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 CDJ91199.1 - 4e-05 23.0 8.7 4e-05 23.0 8.7 1.7 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport TPT PF03151.16 CDJ91199.1 - 0.0012 18.3 12.6 0.0012 18.3 12.6 1.8 1 1 0 1 1 1 1 Triose-phosphate Transporter family CAP_N PF01213.19 CDJ91200.1 - 0.0012 18.4 4.7 0.0019 17.8 4.7 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Trypan_PARP PF05887.11 CDJ91201.1 - 4.2e-07 30.0 123.1 0.022 14.8 10.1 5.9 2 1 1 3 3 3 2 Procyclic acidic repetitive protein (PARP) Beta_helix PF13229.6 CDJ91202.1 - 3.6e-09 36.7 5.1 3.7e-08 33.4 0.6 2.3 1 1 1 2 2 2 2 Right handed beta helix region EGF_2 PF07974.13 CDJ91202.1 - 0.014 15.8 11.6 0.19 12.2 6.8 2.3 2 0 0 2 2 2 0 EGF-like domain DUF4957 PF16318.5 CDJ91202.1 - 0.04 13.9 0.0 1.3 9.0 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4957) PRP4 PF08799.11 CDJ91202.1 - 0.16 11.5 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like rve PF00665.26 CDJ91203.1 - 5e-18 65.4 0.0 1.1e-17 64.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDJ91203.1 - 2.8e-05 23.8 0.1 7.1e-05 22.5 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain Guanylate_cyc PF00211.20 CDJ91204.1 - 5.1e-59 199.0 0.0 6.3e-59 198.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 CDJ91204.1 - 0.0041 16.6 0.1 0.0062 16.0 0.1 1.3 1 0 0 1 1 1 1 Heme NO binding associated RVT_1 PF00078.27 CDJ91205.1 - 8.8e-25 87.5 0.0 1.2e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CH PF00307.31 CDJ91205.1 - 0.13 12.4 0.2 7.2 6.8 0.0 2.8 2 1 1 3 3 3 0 Calponin homology (CH) domain DUF1233 PF06806.12 CDJ91205.1 - 0.17 11.5 0.0 0.41 10.3 0.0 1.6 1 0 0 1 1 1 0 Putative excisionase (DUF1233) WD40 PF00400.32 CDJ91206.1 - 4.2e-05 24.2 1.6 0.1 13.5 0.1 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat WD40 PF00400.32 CDJ91207.1 - 8.4e-06 26.4 0.1 0.0053 17.6 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat TAS2R PF05296.13 CDJ91208.1 - 0.0016 17.6 0.1 0.0022 17.2 0.1 1.2 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) AAA_19 PF13245.6 CDJ91209.1 - 0.0034 17.7 0.0 0.0069 16.7 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 CDJ91209.1 - 0.0042 16.7 0.0 0.0057 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ91209.1 - 0.013 15.3 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CDJ91209.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 CDJ91209.1 - 0.23 11.3 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 Helicase Peptidase_C54 PF03416.19 CDJ91210.1 - 2.2e-77 260.2 0.0 2.9e-77 259.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 His_Phos_2 PF00328.22 CDJ91211.1 - 1.6e-16 60.7 0.2 1.7e-13 50.7 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF2316 PF10078.9 CDJ91212.1 - 0.002 18.3 0.8 0.019 15.2 0.2 2.3 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2316) CENP-F_leu_zip PF10473.9 CDJ91212.1 - 0.0043 17.1 10.2 0.019 15.0 1.4 3.1 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin PF02996.17 CDJ91212.1 - 0.0062 16.4 3.8 2.4 8.1 0.6 3.3 2 1 0 3 3 3 1 Prefoldin subunit FlaC_arch PF05377.11 CDJ91212.1 - 0.0068 16.8 3.2 0.12 12.8 0.0 3.3 2 1 1 3 3 3 1 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.12 CDJ91212.1 - 0.013 15.5 5.8 0.072 13.2 2.6 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4618 PF15397.6 CDJ91212.1 - 0.015 14.8 7.1 0.21 11.0 1.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) LPP PF04728.13 CDJ91212.1 - 0.025 15.0 3.4 4.3 7.8 0.0 3.8 4 0 0 4 4 4 0 Lipoprotein leucine-zipper DUF5082 PF16888.5 CDJ91212.1 - 0.051 13.8 2.9 6.9 7.0 0.5 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF677 PF05055.12 CDJ91212.1 - 0.088 11.7 3.6 0.19 10.6 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF677) bZIP_1 PF00170.21 CDJ91212.1 - 0.11 12.7 10.5 0.19 11.9 0.5 3.7 3 0 0 3 3 3 0 bZIP transcription factor AAA_13 PF13166.6 CDJ91212.1 - 0.15 10.6 5.7 0.23 10.0 5.7 1.4 1 1 0 1 1 1 0 AAA domain Atg14 PF10186.9 CDJ91212.1 - 0.16 11.1 6.1 0.3 10.1 6.1 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GrpE PF01025.19 CDJ91212.1 - 0.24 11.0 5.2 0.51 10.0 1.1 2.9 2 1 1 3 3 3 0 GrpE YabA PF06156.13 CDJ91212.1 - 0.32 11.7 5.9 3.7 8.2 1.2 3.4 1 1 2 3 3 3 0 Initiation control protein YabA CLZ PF16526.5 CDJ91212.1 - 0.32 11.4 4.7 2.7 8.4 0.2 3.3 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GAS PF13851.6 CDJ91212.1 - 0.62 9.4 10.6 0.21 10.9 6.2 2.4 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 CDJ91212.1 - 0.65 10.4 12.1 0.03 14.8 5.2 2.3 3 1 1 4 4 3 0 Fez1 DUF5094 PF17015.5 CDJ91212.1 - 0.71 10.0 3.9 2.1 8.5 3.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) TMF_DNA_bd PF12329.8 CDJ91212.1 - 0.74 9.9 9.0 3.6 7.7 0.6 3.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding HAUS-augmin3 PF14932.6 CDJ91212.1 - 0.75 9.3 5.9 0.48 10.0 2.9 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DivIC PF04977.15 CDJ91212.1 - 0.77 9.6 12.1 0.73 9.6 0.8 3.4 3 1 1 4 4 3 0 Septum formation initiator SlyX PF04102.12 CDJ91212.1 - 0.79 10.4 3.2 25 5.6 0.1 3.5 2 1 1 3 3 3 0 SlyX Spc7 PF08317.11 CDJ91212.1 - 0.97 8.3 7.8 8.1 5.2 8.0 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein ZapB PF06005.12 CDJ91212.1 - 1.3 9.6 9.6 0.69 10.4 2.5 3.5 3 1 0 3 3 2 0 Cell division protein ZapB DUF4988 PF16378.5 CDJ91212.1 - 1.4 8.5 4.9 14 5.3 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function CREPT PF16566.5 CDJ91212.1 - 1.4 9.1 6.8 1.9 8.6 2.9 2.9 1 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour LMBR1 PF04791.16 CDJ91212.1 - 1.5 7.7 2.8 2 7.2 2.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CCDC106 PF15794.5 CDJ91212.1 - 2.2 7.9 14.1 0.036 13.8 2.8 3.0 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 106 DUF724 PF05266.14 CDJ91212.1 - 4 7.2 7.0 2.7 7.8 3.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) T4SS PF07996.11 CDJ91212.1 - 4.3 7.7 6.9 2.6 8.4 1.0 2.9 3 1 1 4 4 3 0 Type IV secretion system proteins Spc24 PF08286.11 CDJ91212.1 - 7.2 6.9 8.7 12 6.2 1.7 3.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Pkinase PF00069.25 CDJ91213.1 - 2.7e-37 128.6 6.2 1.1e-32 113.5 0.2 3.6 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ91213.1 - 8.9e-23 80.9 0.1 8.9e-23 80.9 0.1 3.3 4 0 0 4 4 4 1 Protein tyrosine kinase DUF1475 PF07343.11 CDJ91213.1 - 0.17 11.6 0.0 0.27 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1475) 2OG-FeII_Oxy_2 PF13532.6 CDJ91214.1 - 1.2e-09 38.6 0.0 4.9e-09 36.7 0.1 2.0 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 CDJ91214.1 - 0.15 12.6 0.0 0.27 11.7 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Astacin PF01400.24 CDJ91215.1 - 1e-67 227.5 7.9 4.8e-50 169.8 1.3 3.1 2 1 1 3 3 3 3 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 CDJ91215.1 - 0.051 13.4 0.1 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Matrixin EGF_2 PF07974.13 CDJ91215.1 - 4 7.9 12.2 8.2 6.9 12.2 1.6 1 0 0 1 1 1 0 EGF-like domain Astacin PF01400.24 CDJ91216.1 - 3.2e-56 190.0 1.5 4.6e-56 189.5 1.5 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) DUF4367 PF14285.6 CDJ91216.1 - 0.084 13.3 1.0 0.4 11.1 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) EGF_2 PF07974.13 CDJ91216.1 - 1.4 9.3 13.0 3.6 8.0 13.0 1.7 1 0 0 1 1 1 0 EGF-like domain Astacin PF01400.24 CDJ91217.1 - 7.3e-24 84.4 0.1 1.1e-23 83.8 0.1 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 CDJ91217.1 - 0.17 11.7 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Matrixin zf-H2C2_2 PF13465.6 CDJ91219.1 - 0.051 14.0 2.6 0.051 14.0 2.6 4.0 4 0 0 4 4 4 0 Zinc-finger double domain zf-H2C2_5 PF13909.6 CDJ91219.1 - 0.075 12.8 0.3 0.075 12.8 0.3 4.0 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 CDJ91219.1 - 0.47 11.4 34.6 0.13 13.1 2.9 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-Di19 PF05605.12 CDJ91219.1 - 1.7 9.0 22.8 0.63 10.4 1.6 4.0 3 1 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding GCP_C_terminal PF04130.13 CDJ91220.1 - 1.3e-07 31.4 0.5 2.6e-07 30.4 0.5 1.4 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal MKRN1_C PF15815.5 CDJ91220.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase makorin-1, C-terminal ERM PF00769.19 CDJ91221.1 - 5.5e-23 82.1 21.0 5.5e-23 82.1 21.0 2.9 1 1 0 2 2 2 1 Ezrin/radixin/moesin family FERM_C PF09380.10 CDJ91221.1 - 7.9e-23 80.7 0.1 2.7e-22 78.9 0.1 2.0 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 CDJ91221.1 - 6.3e-20 71.7 0.0 6.3e-20 71.7 0.0 2.5 2 1 1 3 3 3 1 FERM central domain FERM_N PF09379.10 CDJ91221.1 - 5e-12 45.6 0.0 1.2e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain ACBP PF00887.19 CDJ91221.1 - 0.026 14.7 0.0 0.084 13.1 0.0 1.8 1 0 0 1 1 1 0 Acyl CoA binding protein Glyoxalase PF00903.25 CDJ91221.1 - 0.32 11.2 1.2 1.2 9.4 1.1 2.0 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PTH2 PF01981.16 CDJ91221.1 - 3.2 8.1 5.0 13 6.1 5.1 1.9 1 1 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 DUF1664 PF07889.12 CDJ91221.1 - 4.4 7.4 8.5 1.3 9.1 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) FmiP_Thoc5 PF09766.9 CDJ91221.1 - 6.8 5.9 19.0 4.2 6.6 12.4 2.2 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 FmiP_Thoc5 PF09766.9 CDJ91222.1 - 2.1e-84 283.9 0.3 2.9e-84 283.5 0.3 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 RWD PF05773.22 CDJ91222.1 - 0.058 13.7 0.1 0.33 11.3 0.0 2.2 2 0 0 2 2 2 0 RWD domain HTH_Tnp_Tc3_2 PF01498.18 CDJ91223.1 - 2.4e-21 75.7 0.3 4.3e-21 74.9 0.3 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 CDJ91223.1 - 6.5e-11 42.2 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 CDJ91223.1 - 1.1e-05 26.0 0.2 1.1e-05 26.0 0.2 2.7 3 0 0 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.6 CDJ91223.1 - 0.0023 17.7 0.1 0.0023 17.7 0.1 2.4 3 0 0 3 3 3 1 Homeodomain-like domain PAX PF00292.18 CDJ91223.1 - 0.0024 17.8 0.6 0.0042 17.0 0.6 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_28 PF13518.6 CDJ91223.1 - 0.016 15.3 0.2 0.065 13.4 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 CDJ91223.1 - 0.069 12.8 0.1 3.7 7.3 0.0 3.0 3 0 0 3 3 3 0 Sigma-70, region 4 LZ_Tnp_IS481 PF13011.6 CDJ91223.1 - 0.1 13.1 0.5 0.24 11.9 0.5 1.7 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 zf-C2H2_4 PF13894.6 CDJ91225.1 - 1.1e-09 38.3 28.0 0.037 14.9 0.4 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.26 CDJ91225.1 - 4.1e-08 33.3 29.4 0.029 14.8 3.8 5.5 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ91225.1 - 6.2e-08 32.7 20.5 1.3e-05 25.4 0.6 4.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_3rep PF18868.1 CDJ91225.1 - 0.00049 20.8 5.5 0.28 11.8 5.7 3.2 2 1 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 CDJ91225.1 - 0.021 15.1 7.9 0.58 10.5 0.2 4.3 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 CDJ91225.1 - 0.088 12.9 5.4 0.52 10.5 1.9 2.7 2 0 0 2 2 2 0 Zinc ribbon domain RIG-I_C-RD PF11648.8 CDJ91225.1 - 0.28 11.4 4.4 0.1 12.9 1.2 1.8 2 0 0 2 2 2 0 C-terminal domain of RIG-I DUF2197 PF09963.9 CDJ91225.1 - 0.6 10.4 6.8 2.7 8.3 1.3 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) DUF629 PF04780.12 CDJ91225.1 - 0.83 8.1 8.0 3.8 5.9 2.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF629) ADK_lid PF05191.14 CDJ91225.1 - 1.1 9.3 5.2 9.4 6.3 0.4 3.0 2 1 2 4 4 4 0 Adenylate kinase, active site lid zf_C2H2_ZHX PF18387.1 CDJ91225.1 - 1.2 8.9 9.0 0.78 9.4 0.7 3.4 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain FOXP-CC PF16159.5 CDJ91225.1 - 1.4 9.6 12.9 0.86 10.3 0.4 3.2 1 1 1 3 3 3 0 FOXP coiled-coil domain Actin_micro PF17003.5 CDJ91225.1 - 1.5 7.9 7.6 1.5 7.9 2.3 2.2 1 1 1 2 2 2 0 Putative actin-like family zf-C2H2_8 PF15909.5 CDJ91225.1 - 1.9 8.9 9.0 71 3.8 8.8 2.4 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 CDJ91225.1 - 3.5 7.5 19.4 0.064 13.0 1.7 4.1 3 1 0 3 3 3 0 zinc-finger C2H2-type Ank_2 PF12796.7 CDJ91226.1 - 3.3e-60 200.7 18.8 8e-12 45.6 0.1 10.7 7 2 7 14 14 14 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ91226.1 - 2e-37 127.1 15.9 5.4e-07 30.0 0.1 13.3 7 3 9 16 16 16 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ91226.1 - 2.9e-35 119.9 12.2 7.9e-05 22.9 0.0 13.2 11 3 3 14 14 14 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ91226.1 - 2.8e-33 110.2 22.5 0.01 16.3 0.1 15.5 17 0 0 17 17 17 9 Ankyrin repeat Ank PF00023.30 CDJ91226.1 - 2.5e-29 100.4 17.3 0.00016 22.0 0.1 13.8 14 0 0 14 14 14 9 Ankyrin repeat Collagen PF01391.18 CDJ91227.1 - 5.2e-23 80.6 84.9 1.7e-09 37.3 28.1 4.2 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ91227.1 - 1.4e-06 28.2 1.9 2e-06 27.8 1.9 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Spec3 PF15795.5 CDJ91228.1 - 2.2e-31 108.3 6.2 3.3e-31 107.7 6.2 1.3 1 0 0 1 1 1 1 Ectodermal ciliogenesis protein zf-H2C2_2 PF13465.6 CDJ91230.1 - 0.00021 21.6 5.7 0.0062 16.9 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDJ91230.1 - 0.00039 21.0 18.1 0.004 17.9 1.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CDJ91230.1 - 0.0016 18.8 0.8 0.0016 18.8 0.8 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.7 CDJ91230.1 - 0.22 12.0 0.2 0.22 12.0 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf_UBZ PF18439.1 CDJ91230.1 - 0.31 10.7 4.6 0.25 11.0 1.3 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 CDJ91230.1 - 0.75 9.9 4.5 0.82 9.7 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ91230.1 - 2.4 8.5 11.4 2.6 8.4 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CDJ91230.1 - 9.7 6.6 12.9 17 5.8 0.5 3.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF866 PF05907.13 CDJ91231.1 - 2e-23 83.0 0.2 4.6e-23 81.8 0.2 1.6 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) RVT_1 PF00078.27 CDJ91231.1 - 2.1e-19 69.9 0.0 5.7e-19 68.5 0.0 1.7 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RPAP3_C PF13877.6 CDJ91231.1 - 0.039 14.5 1.1 17 6.0 0.1 2.9 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 MtrA PF04208.14 CDJ91231.1 - 0.04 13.6 0.5 12 5.5 0.1 2.6 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit A Retrotran_gag_2 PF14223.6 CDJ91231.1 - 0.08 12.6 2.0 14 5.3 0.1 3.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type KapB PF08810.10 CDJ91231.1 - 0.082 13.1 0.1 0.082 13.1 0.1 3.0 3 0 0 3 3 3 0 Kinase associated protein B zf-C2H2_10 PF16588.5 CDJ91231.1 - 0.089 12.5 0.5 0.2 11.4 0.5 1.6 1 0 0 1 1 1 0 C2H2 zinc-finger XhlA PF10779.9 CDJ91231.1 - 2.5 8.4 9.0 22 5.3 0.4 3.8 3 0 0 3 3 3 0 Haemolysin XhlA CNOT11 PF10155.9 CDJ91232.1 - 2.7e-21 76.0 0.6 7.1e-21 74.7 0.2 1.9 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 11 Tfb2 PF03849.14 CDJ91233.1 - 3.5e-43 148.0 0.1 3.9e-43 147.8 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Exog_C PF18026.1 CDJ91234.1 - 0.081 13.0 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Endo/exonuclease (EXOG) C-terminal domain Tfb2_C PF18307.1 CDJ91235.1 - 4.9e-22 78.1 0.3 7.2e-22 77.6 0.3 1.3 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Tfb2 PF03849.14 CDJ91235.1 - 3e-12 46.2 0.0 3.7e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.6 CDJ91235.1 - 0.00017 21.7 0.0 0.00023 21.3 0.0 1.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Alg14 PF08660.11 CDJ91235.1 - 0.17 11.8 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like PUB_1 PF18486.1 CDJ91236.1 - 0.041 13.7 0.2 0.093 12.6 0.2 1.6 1 0 0 1 1 1 0 PNGase/UBA- or UBX-containing domain 7tm_1 PF00001.21 CDJ91236.1 - 0.049 13.0 10.9 0.083 12.2 10.9 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) zf-3CxxC_2 PF17180.4 CDJ91237.1 - 1.3e-15 57.9 2.0 1.3e-15 57.9 2.0 2.0 3 0 0 3 3 3 1 Zinc-binding domain zf-CCHC_2 PF13696.6 CDJ91237.1 - 1.2e-08 34.6 6.6 1.2e-08 34.6 6.6 2.6 3 0 0 3 3 3 1 Zinc knuckle UPF0515 PF15135.6 CDJ91237.1 - 2.1e-06 27.3 5.8 3.2e-06 26.7 5.8 1.2 1 0 0 1 1 1 1 Uncharacterised protein UPF0515 zf-C2H2_11 PF16622.5 CDJ91237.1 - 0.0078 15.9 0.2 0.0078 15.9 0.2 2.4 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-3CxxC PF13695.6 CDJ91237.1 - 0.02 15.3 7.1 0.02 15.3 7.1 2.2 2 1 0 2 2 2 0 Zinc-binding domain zf-CCHC PF00098.23 CDJ91237.1 - 0.055 13.6 2.8 0.055 13.6 2.8 2.6 3 0 0 3 3 3 0 Zinc knuckle zf-C2H2_4 PF13894.6 CDJ91237.1 - 3.5 8.7 7.8 4.7 8.3 0.3 3.4 2 1 1 3 3 3 0 C2H2-type zinc finger BAR PF03114.18 CDJ91238.1 - 0.0011 18.7 6.6 0.0012 18.5 6.6 1.1 1 0 0 1 1 1 1 BAR domain SIP1 PF04938.12 CDJ91239.1 - 8.1e-46 156.5 0.1 9.6e-46 156.2 0.1 1.0 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) FAD_binding_2 PF00890.24 CDJ91240.1 - 1.4e-89 301.1 0.5 1.6e-89 300.9 0.5 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CDJ91240.1 - 1.3e-09 38.1 4.1 6.8e-09 35.8 2.9 2.4 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CDJ91240.1 - 4.2e-09 36.3 2.8 2.6e-08 33.7 2.8 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CDJ91240.1 - 5.8e-07 29.0 1.4 1.8e-06 27.4 1.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDJ91240.1 - 1.7e-06 28.2 0.3 9.9e-06 25.7 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CDJ91240.1 - 3.7e-06 26.3 3.0 0.00028 20.1 0.2 2.8 3 0 0 3 3 3 2 Glucose inhibited division protein A HI0933_like PF03486.14 CDJ91240.1 - 4.5e-06 25.6 5.3 0.00017 20.4 0.9 2.9 3 0 0 3 3 3 2 HI0933-like protein AlaDh_PNT_C PF01262.21 CDJ91240.1 - 0.00089 18.6 0.4 0.0061 15.9 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 CDJ91240.1 - 0.0028 17.0 0.2 0.018 14.3 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CDJ91240.1 - 0.0062 16.5 0.2 1.7 8.6 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 CDJ91240.1 - 0.03 13.6 4.9 0.046 13.0 1.3 2.6 2 1 1 3 3 3 0 Thi4 family Pyr_redox PF00070.27 CDJ91240.1 - 0.031 14.8 1.1 0.1 13.2 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CDJ91240.1 - 0.035 13.4 0.7 0.076 12.3 0.6 1.5 1 1 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 CDJ91240.1 - 0.04 14.4 0.1 0.56 10.7 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 CDJ91240.1 - 0.054 12.5 1.3 0.2 10.7 0.6 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.24 CDJ91240.1 - 0.073 12.3 1.6 2.9 7.1 0.2 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase TPR_1 PF00515.28 CDJ91242.1 - 2.7e-22 77.6 9.8 2.3e-05 24.0 0.0 5.7 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ91242.1 - 5.7e-22 76.0 18.0 7.3e-05 22.6 0.0 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ91242.1 - 3.2e-21 73.7 11.3 1.4e-06 28.0 0.0 6.0 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ91242.1 - 4.9e-20 70.9 8.8 0.00014 21.5 0.1 5.9 5 1 1 6 6 6 4 TPR repeat TPR_12 PF13424.6 CDJ91242.1 - 7.4e-19 67.8 13.3 5.2e-08 33.1 0.1 5.5 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ91242.1 - 3.1e-13 50.0 8.2 0.00084 19.8 0.1 5.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ91242.1 - 2e-12 46.8 7.2 0.00098 19.8 0.1 5.4 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ91242.1 - 9.2e-10 37.9 6.9 0.001 18.9 0.0 5.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ91242.1 - 1.3e-09 38.5 11.7 0.0016 19.0 0.0 5.1 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ91242.1 - 7.3e-08 32.6 10.8 0.038 14.6 0.0 6.2 6 1 1 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ91242.1 - 8.4e-08 32.3 6.9 0.00011 22.4 0.5 4.2 1 1 4 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CDJ91242.1 - 2.3e-07 30.4 5.9 0.043 13.7 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ91242.1 - 1.5e-05 25.1 13.2 0.013 15.8 0.3 6.0 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ91242.1 - 9.5e-05 22.5 2.7 1.4 9.1 0.3 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat NARP1 PF12569.8 CDJ91242.1 - 0.00042 19.4 0.5 0.71 8.7 0.1 2.4 2 1 0 2 2 2 2 NMDA receptor-regulated protein 1 RPN7 PF10602.9 CDJ91242.1 - 0.009 15.7 1.1 2.8 7.6 0.1 2.6 1 1 1 2 2 2 2 26S proteasome subunit RPN7 BTAD PF03704.17 CDJ91242.1 - 0.0098 16.3 1.2 4 7.9 0.1 3.0 2 1 0 2 2 2 1 Bacterial transcriptional activator domain PPR PF01535.20 CDJ91242.1 - 0.014 15.6 2.4 3.4 8.1 0.1 3.7 3 0 0 3 3 3 0 PPR repeat TPR_20 PF14561.6 CDJ91242.1 - 0.018 15.4 1.4 0.47 10.8 0.0 3.0 3 1 0 4 4 2 0 Tetratricopeptide repeat DUF3808 PF10300.9 CDJ91242.1 - 0.019 13.7 0.3 0.052 12.3 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3808) TPR_4 PF07721.14 CDJ91242.1 - 0.062 14.0 3.7 44 5.1 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat Sel1 PF08238.12 CDJ91242.1 - 8.1 7.3 13.3 26 5.7 0.2 4.6 3 1 1 4 4 4 0 Sel1 repeat DAGK_acc PF00609.19 CDJ91243.1 - 3.8e-52 176.8 0.0 6.6e-52 176.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain C1_1 PF00130.22 CDJ91243.1 - 2.5e-22 78.5 27.4 1.8e-12 46.9 9.5 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DAGK_cat PF00781.24 CDJ91243.1 - 1.4e-15 57.0 0.0 3.4e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain EF-hand_1 PF00036.32 CDJ91243.1 - 2.8e-08 32.7 0.6 0.001 18.4 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDJ91243.1 - 3.1e-07 30.8 0.2 7.4e-07 29.5 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ91243.1 - 3.3e-06 26.6 0.3 0.0044 16.9 0.1 3.2 1 1 1 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDJ91243.1 - 1.2e-05 24.6 0.3 0.0027 17.1 0.1 2.8 2 0 0 2 2 2 1 EF hand C1_2 PF03107.16 CDJ91243.1 - 0.023 15.0 16.0 0.07 13.4 4.7 2.6 2 0 0 2 2 2 0 C1 domain SPARC_Ca_bdg PF10591.9 CDJ91243.1 - 0.029 14.7 0.5 0.35 11.2 0.1 2.9 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Zf_RING PF16744.5 CDJ91243.1 - 8.1 6.6 18.1 12 6.1 7.8 3.0 1 1 1 2 2 2 0 KIAA1045 RING finger DUF953 PF06110.11 CDJ91244.1 - 8e-38 128.7 0.1 9e-38 128.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 CDJ91244.1 - 0.0067 16.2 0.0 0.055 13.3 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Frizzled PF01534.17 CDJ91245.1 - 0.0051 15.9 0.0 0.0059 15.7 0.0 1.0 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region STE3 PF02076.15 CDJ91245.1 - 0.011 14.9 0.5 0.014 14.6 0.5 1.1 1 0 0 1 1 1 0 Pheromone A receptor Peptidase_M22 PF00814.25 CDJ91246.1 - 5e-90 301.9 0.0 6.1e-90 301.6 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Complex1_LYR PF05347.15 CDJ91246.1 - 3.6e-07 30.1 0.9 7.7e-07 29.1 0.9 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CDJ91246.1 - 0.0085 16.8 0.1 0.015 16.0 0.1 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 CDJ91246.1 - 0.034 14.7 0.1 0.077 13.6 0.1 1.6 1 1 0 1 1 1 0 Complex1_LYR-like Carbam_trans_N PF02543.15 CDJ91246.1 - 0.046 13.4 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus Tmemb_55A PF09788.9 CDJ91247.1 - 1.9e-68 230.2 10.1 2.1e-68 230.1 10.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 55A ANTH PF07651.16 CDJ91248.1 - 5.4e-69 232.3 1.2 7.6e-69 231.8 0.0 1.9 2 0 0 2 2 2 1 ANTH domain I_LWEQ PF01608.17 CDJ91248.1 - 7e-52 175.7 14.5 7e-52 175.7 14.5 4.9 3 2 1 4 4 4 1 I/LWEQ domain Baculo_gp64 PF03273.13 CDJ91248.1 - 0.59 8.9 2.6 0.33 9.7 0.4 1.6 2 0 0 2 2 2 0 Baculovirus gp64 envelope glycoprotein family MscS_porin PF12795.7 CDJ91248.1 - 1.6 8.2 45.0 0.19 11.2 12.6 3.9 3 1 1 4 4 4 0 Mechanosensitive ion channel porin domain zf-RING_UBOX PF13445.6 CDJ91249.1 - 1e-08 35.0 0.4 2e-08 34.1 0.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDJ91249.1 - 1.6e-08 34.2 1.6 3.3e-08 33.2 1.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ91249.1 - 3.5e-08 33.2 0.9 7.9e-08 32.1 0.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ91249.1 - 8.9e-08 32.2 1.7 2e-07 31.1 1.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CDJ91249.1 - 4.6e-06 26.9 2.1 8.9e-06 25.9 2.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDJ91249.1 - 1.1e-05 25.2 1.9 2.4e-05 24.1 1.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ91249.1 - 0.0002 21.2 3.0 0.00056 19.8 3.1 1.8 1 1 0 1 1 1 1 zinc-RING finger domain DUF2645 PF10840.8 CDJ91249.1 - 0.0018 18.8 0.2 0.0039 17.8 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2645) zf-RING_11 PF17123.5 CDJ91249.1 - 0.068 12.9 4.3 0.75 9.6 4.9 2.3 1 1 1 2 2 2 0 RING-like zinc finger Prok-RING_4 PF14447.6 CDJ91249.1 - 0.082 12.8 5.9 0.32 10.9 5.8 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Cpn60_TCP1 PF00118.24 CDJ91250.1 - 1.7e-86 290.8 16.6 3.6e-86 289.8 16.6 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Gag_p15 PF08723.10 CDJ91250.1 - 0.033 14.4 0.4 0.68 10.2 0.0 2.8 2 1 1 3 3 3 0 Gag protein p15 tRNA_int_endo PF01974.17 CDJ91250.1 - 0.16 12.0 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 tRNA intron endonuclease, catalytic C-terminal domain Cpn10 PF00166.21 CDJ91251.1 - 1.3e-33 114.9 0.0 1.5e-33 114.7 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Polyketide_cyc PF03364.20 CDJ91252.1 - 1.2e-17 64.3 0.0 1.5e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 CDJ91252.1 - 0.0066 16.7 0.0 0.0088 16.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport zf-C2H2_6 PF13912.6 CDJ91253.1 - 5.8e-05 23.0 0.4 0.00018 21.4 0.4 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_9 PF16293.5 CDJ91253.1 - 0.57 10.1 2.5 15 5.5 0.0 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 CDJ91253.1 - 2.8 8.3 8.7 3.5 8.0 0.4 2.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 CDJ91253.1 - 3.4 8.3 6.4 0.33 11.5 1.4 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type SAP PF02037.27 CDJ91254.1 - 1.9e-09 37.1 0.2 3.2e-09 36.3 0.2 1.4 1 0 0 1 1 1 1 SAP domain RPN2_C PF18004.1 CDJ91256.1 - 4.5e-43 146.9 6.9 1.6e-42 145.1 6.9 1.9 1 1 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 CDJ91256.1 - 3.7e-16 58.7 5.6 4.4e-08 33.2 0.2 4.8 4 0 0 4 4 4 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CDJ91256.1 - 9e-11 42.0 0.0 2.2e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.6 CDJ91256.1 - 0.00019 21.8 0.0 0.0031 18.0 0.0 2.6 2 0 0 2 2 2 1 HEAT-like repeat Cnd1 PF12717.7 CDJ91256.1 - 0.0011 19.1 0.0 1.4 8.9 0.0 2.4 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CDJ91256.1 - 0.0015 18.6 0.0 17 6.0 0.0 3.6 3 0 0 3 3 3 2 HEAT repeat PDZ PF00595.24 CDJ91257.1 - 1.9e-05 24.9 0.0 4.3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDJ91257.1 - 0.00048 19.9 0.0 0.0014 18.5 0.0 1.8 1 0 0 1 1 1 1 PDZ domain DUF1296 PF06972.11 CDJ91257.1 - 0.089 12.9 0.1 0.25 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Secretin_N PF03958.17 CDJ91257.1 - 0.16 12.4 0.4 9.2 6.7 0.1 2.6 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain HTH_26 PF13443.6 CDJ91258.1 - 0.0036 17.7 0.0 0.0063 16.9 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain DUF3602 PF12223.8 CDJ91258.1 - 0.02 15.5 0.1 0.025 15.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) HTH_IclR PF09339.10 CDJ91258.1 - 0.042 13.6 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_32 PF13565.6 CDJ91258.1 - 0.093 13.4 0.4 0.14 12.8 0.4 1.5 1 1 0 1 1 1 0 Homeodomain-like domain LacI PF00356.21 CDJ91258.1 - 0.11 12.3 0.3 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Aldedh PF00171.22 CDJ91259.1 - 4e-101 338.8 0.0 5.5e-101 338.3 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DSHCT PF08148.12 CDJ91260.1 - 5.8e-45 152.9 0.1 5.8e-45 152.9 0.1 1.5 2 0 0 2 2 2 1 DSHCT (NUC185) domain WRW PF10206.9 CDJ91260.1 - 0.099 13.0 0.2 0.25 11.7 0.2 1.7 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f C2 PF00168.30 CDJ91262.1 - 5.9e-18 65.1 0.0 1.2e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain PDZ_6 PF17820.1 CDJ91262.1 - 0.00029 20.6 0.1 0.00064 19.5 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CDJ91262.1 - 0.0017 18.7 0.3 0.0028 17.9 0.3 1.3 1 0 0 1 1 1 1 PDZ domain PI3K_C2 PF00792.24 CDJ91262.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 Vhr1 PF04001.13 CDJ91262.1 - 0.021 15.1 0.6 1 9.7 0.0 2.4 2 0 0 2 2 2 0 Transcription factor Vhr1 PIG-U PF06728.13 CDJ91263.1 - 1.5e-65 221.7 32.7 2.1e-65 221.3 32.7 1.2 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Ctf8 PF09696.10 CDJ91264.1 - 3e-10 40.6 1.1 3.6e-07 30.6 0.2 2.8 1 1 1 2 2 2 2 Ctf8 CHCH PF06747.13 CDJ91266.1 - 0.00011 22.2 8.6 0.00014 21.8 8.6 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 CDJ91266.1 - 0.00012 22.3 4.1 0.00017 21.8 4.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Ski_Sno PF02437.17 CDJ91267.1 - 1.9e-32 111.2 0.0 3.9e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 SKI/SNO/DAC family Cofilin_ADF PF00241.20 CDJ91268.1 - 1.5e-29 102.3 0.1 1.7e-29 102.1 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein RNase_H2-Ydr279 PF09468.10 CDJ91268.1 - 0.049 13.8 0.6 0.067 13.4 0.6 1.5 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain Kelch_4 PF13418.6 CDJ91269.1 - 1.6e-09 37.6 0.3 0.00084 19.3 0.0 4.8 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ91269.1 - 5.7e-09 36.0 1.1 0.0025 18.0 0.0 3.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CDJ91269.1 - 1.2e-08 34.4 7.5 0.058 13.0 0.1 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 CDJ91269.1 - 3.1e-07 30.2 3.6 0.55 10.3 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 CDJ91269.1 - 3.3e-05 24.0 4.5 0.21 12.0 0.2 4.1 3 1 1 4 4 4 2 Kelch motif Kelch_2 PF07646.15 CDJ91269.1 - 0.013 15.5 6.3 1.9 8.6 0.1 3.9 4 0 0 4 4 4 0 Kelch motif FAD-oxidase_C PF02913.19 CDJ91270.1 - 1.5e-56 191.8 0.0 2.1e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CDJ91270.1 - 6.8e-35 119.8 0.0 1.2e-34 119.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CDJ91270.1 - 0.054 13.6 0.3 0.17 12.1 0.0 2.0 2 0 0 2 2 2 0 Berberine and berberine like Astacin PF01400.24 CDJ91271.1 - 2.4e-71 239.3 0.1 3.7e-71 238.7 0.1 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) ShK PF01549.24 CDJ91271.1 - 1.4e-17 63.9 21.8 1.2e-08 35.4 6.4 2.5 2 0 0 2 2 2 2 ShK domain-like Mucin PF01456.17 CDJ91271.1 - 0.019 14.9 31.9 0.038 14.0 31.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Peptidase_M10 PF00413.24 CDJ91271.1 - 0.11 12.3 1.0 4.3 7.2 0.1 2.8 3 0 0 3 3 3 0 Matrixin 7TM_GPCR_Srz PF10325.9 CDJ91272.1 - 1.8e-05 24.2 27.7 2.5e-05 23.7 27.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srz 7TM_GPCR_Srx PF10328.9 CDJ91272.1 - 0.00013 21.8 22.5 0.00031 20.5 22.5 1.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx HTH_Tnp_Tc3_2 PF01498.18 CDJ91274.1 - 1.5e-15 57.1 1.4 3.9e-15 55.8 0.2 2.1 2 1 0 2 2 2 1 Transposase PAX PF00292.18 CDJ91274.1 - 1.3e-06 28.4 0.3 1.7e-06 28.0 0.3 1.2 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 CDJ91274.1 - 3.4e-06 26.7 1.7 0.00012 21.7 0.0 2.8 3 1 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 CDJ91274.1 - 2.1e-05 25.1 1.4 4.7e-05 23.9 0.2 2.1 2 1 1 3 3 3 1 Homeodomain-like domain GerE PF00196.19 CDJ91274.1 - 0.00036 20.0 0.2 0.015 14.8 0.0 2.5 2 1 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_29 PF13551.6 CDJ91274.1 - 0.00046 20.2 3.0 0.0025 17.8 0.4 2.7 2 1 0 2 2 2 1 Winged helix-turn helix Sigma70_r4_2 PF08281.12 CDJ91274.1 - 0.00053 19.6 0.4 0.009 15.7 0.0 2.5 2 1 0 2 2 2 1 Sigma-70, region 4 HTH_28 PF13518.6 CDJ91274.1 - 0.0017 18.4 0.0 0.1 12.7 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 CDJ91274.1 - 0.0034 17.2 3.0 8 6.4 0.0 3.6 3 1 0 3 3 3 2 MarR family HTH_7 PF02796.15 CDJ91274.1 - 0.074 13.1 4.1 1.8 8.7 0.1 3.9 4 0 0 4 4 4 0 Helix-turn-helix domain of resolvase HTH_38 PF13936.6 CDJ91274.1 - 0.28 11.0 0.2 0.28 11.0 0.2 2.5 3 1 1 4 4 4 0 Helix-turn-helix domain ubiquitin PF00240.23 CDJ91276.1 - 3.7e-09 36.2 0.0 7.6e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family zf-AN1 PF01428.16 CDJ91276.1 - 5.7e-06 26.4 9.5 1.1e-05 25.5 9.5 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Ubiquitin_4 PF18036.1 CDJ91276.1 - 0.0057 16.7 0.1 3.6 7.7 0.0 3.0 2 1 1 3 3 3 2 Ubiquitin-like domain TBK1_ULD PF18396.1 CDJ91276.1 - 0.023 14.6 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD PF11976.8 CDJ91276.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UDPGP PF01704.18 CDJ91277.1 - 3e-147 490.6 0.0 3.5e-147 490.4 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase WD-3 PF09765.9 CDJ91277.1 - 0.045 13.1 0.2 0.096 12.0 0.2 1.5 1 0 0 1 1 1 0 WD-repeat region Complex1_LYR PF05347.15 CDJ91277.1 - 0.11 12.6 0.5 3.8 7.7 0.0 2.5 1 1 1 2 2 2 0 Complex 1 protein (LYR family) Homeodomain PF00046.29 CDJ91278.1 - 1.6e-21 75.9 6.5 2.6e-21 75.2 6.5 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ91278.1 - 0.007 16.3 0.3 0.016 15.1 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain Rap_GAP PF02145.15 CDJ91278.1 - 0.031 13.8 0.1 0.049 13.2 0.1 1.2 1 0 0 1 1 1 0 Rap/ran-GAP Homez PF11569.8 CDJ91278.1 - 0.062 12.8 0.3 0.15 11.5 0.3 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DUF5356 PF17309.2 CDJ91278.1 - 0.067 13.2 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5356) MRP-63 PF14978.6 CDJ91278.1 - 0.5 11.0 2.6 0.81 10.3 2.6 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome protein 63 Cyt-b5 PF00173.28 CDJ91280.1 - 1.2e-13 51.0 0.1 1.6e-13 50.6 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ThiS PF02597.20 CDJ91280.1 - 0.13 12.9 0.0 0.35 11.5 0.0 1.7 2 0 0 2 2 2 0 ThiS family PAP_assoc PF03828.19 CDJ91282.1 - 2.1e-09 37.5 1.4 0.0023 18.1 0.0 3.0 2 0 0 2 2 2 2 Cid1 family poly A polymerase Polbeta PF18765.1 CDJ91282.1 - 7.1e-05 22.8 0.1 0.078 13.1 0.0 3.0 2 0 0 2 2 2 2 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 CDJ91282.1 - 0.011 16.0 0.1 0.19 12.1 0.0 2.8 2 0 0 2 2 2 0 Nucleotidyltransferase domain zf-met PF12874.7 CDJ91282.1 - 6.6 7.3 8.6 3.3 8.2 5.0 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDJ91282.1 - 9.8 6.6 8.2 3 8.2 4.6 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding ShK PF01549.24 CDJ91283.1 - 0.0013 19.2 0.4 0.002 18.6 0.4 1.3 1 0 0 1 1 1 1 ShK domain-like Paf67 PF10255.9 CDJ91285.1 - 0.041 12.9 0.1 0.052 12.5 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 Yip1 PF04893.17 CDJ91286.1 - 2e-08 34.1 18.8 4.5e-08 33.0 16.2 2.0 1 1 1 2 2 2 2 Yip1 domain zf-RanBP PF00641.18 CDJ91287.1 - 1.5e-07 30.6 19.1 3.9e-06 26.1 8.4 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 CDJ91287.1 - 0.012 15.7 10.0 0.066 13.3 10.1 2.1 1 1 1 2 2 2 0 Double zinc ribbon Neuromodulin PF06614.11 CDJ91289.1 - 0.033 14.3 1.4 0.051 13.7 1.4 1.3 1 0 0 1 1 1 0 Neuromodulin SUI1 PF01253.22 CDJ91291.1 - 2.1e-21 76.2 0.9 3.5e-21 75.5 0.9 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 Ribosomal_S17e PF00833.18 CDJ91292.1 - 5.9e-61 203.8 2.4 6.8e-61 203.6 2.4 1.0 1 0 0 1 1 1 1 Ribosomal S17 Cadherin_3 PF16184.5 CDJ91293.1 - 8.4e-162 528.0 13.1 1.5e-21 76.5 0.1 14.2 13 1 1 14 14 14 14 Cadherin-like Big_9 PF17963.1 CDJ91293.1 - 5.6e-06 27.0 19.5 1.3 9.8 0.1 9.5 10 1 0 10 10 10 2 Bacterial Ig domain Adeno_E3_CR2 PF02439.15 CDJ91293.1 - 0.012 15.4 0.3 0.027 14.2 0.3 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4576 PF15144.6 CDJ91293.1 - 0.13 12.2 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) Cadherin_4 PF17803.1 CDJ91293.1 - 1.6 9.4 19.9 1.8 9.2 0.3 7.7 8 1 0 8 8 8 0 Bacterial cadherin-like domain TSP_1 PF00090.19 CDJ91294.1 - 5.3e-06 26.6 18.8 5.5e-05 23.3 2.3 2.5 2 0 0 2 2 2 2 Thrombospondin type 1 domain SKA2 PF16740.5 CDJ91294.1 - 0.062 13.1 0.7 1.6 8.6 0.0 2.6 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Sec1 PF00995.23 CDJ91295.1 - 1.3e-117 394.5 2.6 1.5e-117 394.3 2.6 1.0 1 0 0 1 1 1 1 Sec1 family COG6 PF06419.11 CDJ91296.1 - 1.2e-144 482.9 15.3 1.2e-144 482.9 15.3 1.3 2 0 0 2 2 2 1 Conserved oligomeric complex COG6 Sec34 PF04136.15 CDJ91296.1 - 4.6e-05 23.3 3.6 4.6e-05 23.3 3.6 2.7 3 1 0 3 3 3 1 Sec34-like family Jnk-SapK_ap_N PF09744.9 CDJ91296.1 - 0.0017 18.6 9.3 0.0017 18.6 9.3 2.9 3 0 0 3 3 3 1 JNK_SAPK-associated protein-1 Fmp27_WPPW PF10359.9 CDJ91296.1 - 0.0054 15.6 8.5 0.0098 14.8 8.5 1.3 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain COG2 PF06148.11 CDJ91296.1 - 0.017 15.2 2.9 0.017 15.2 2.9 2.9 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4752 PF15944.5 CDJ91296.1 - 0.14 12.3 0.1 15 5.7 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4752) DUF1043 PF06295.12 CDJ91296.1 - 0.43 10.6 9.2 0.5 10.4 6.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) ATG16 PF08614.11 CDJ91296.1 - 0.84 9.8 17.0 21 5.3 14.9 3.2 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 CDJ91296.1 - 1.2 9.1 4.4 5.3 7.1 1.1 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Sec8_exocyst PF04048.14 CDJ91296.1 - 1.6 8.7 8.3 0.24 11.3 3.2 2.3 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain Occludin_ELL PF07303.13 CDJ91296.1 - 1.7 9.4 7.4 5.6 7.8 5.8 2.6 3 0 0 3 3 3 0 Occludin homology domain DUF4795 PF16043.5 CDJ91296.1 - 1.8 8.1 10.9 7.2 6.2 10.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) GAT PF03127.14 CDJ91296.1 - 8.3 6.8 12.4 2.3 8.6 3.2 3.8 3 0 0 3 3 3 0 GAT domain BLOC1_2 PF10046.9 CDJ91296.1 - 9 6.7 12.6 2.8 8.3 0.4 3.4 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1744 PF08490.12 CDJ91297.1 - 3.6e-100 335.3 0.0 5.2e-100 334.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 CDJ91297.1 - 2.9e-75 253.5 1.5 6.4e-75 252.4 1.5 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 CDJ91297.1 - 7.4e-13 48.0 0.2 1.2e-11 44.1 0.1 2.9 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 CDJ91297.1 - 5.4e-08 32.8 1.3 9.2e-08 32.0 0.1 2.0 2 0 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 CDJ91297.1 - 2.7e-07 30.7 0.3 1.2e-06 28.6 0.1 2.2 2 0 0 2 2 2 1 RNase_H superfamily DUF4604 PF15377.6 CDJ91297.1 - 0.055 13.9 0.6 0.11 13.0 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) PHD PF00628.29 CDJ91299.1 - 2.5e-08 33.7 12.9 5.1e-08 32.7 12.9 1.6 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 CDJ91299.1 - 0.00022 21.7 0.1 0.00022 21.7 0.1 5.6 4 2 0 4 4 4 1 SET domain PHD_3 PF13922.6 CDJ91299.1 - 0.13 12.6 0.2 0.58 10.6 0.2 2.1 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx PHD_2 PF13831.6 CDJ91299.1 - 0.13 11.8 4.9 0.26 10.9 4.9 1.4 1 0 0 1 1 1 0 PHD-finger NUC153 PF08159.12 CDJ91300.1 - 3e-05 23.8 1.9 6.5e-05 22.7 1.9 1.6 1 0 0 1 1 1 1 NUC153 domain ANAPC4_WD40 PF12894.7 CDJ91300.1 - 0.018 15.3 0.0 0.19 12.1 0.0 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ91300.1 - 0.15 13.0 0.7 3.1 8.8 0.0 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat Radical_SAM PF04055.21 CDJ91301.1 - 4.7e-31 108.4 1.1 2e-30 106.4 0.0 2.5 3 0 0 3 3 3 1 Radical SAM superfamily UPF0004 PF00919.20 CDJ91301.1 - 5e-27 93.8 0.6 1.3e-26 92.4 0.5 1.8 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 CDJ91301.1 - 3.5e-12 46.1 0.0 6.6e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 TRAM domain RRM_1 PF00076.22 CDJ91302.1 - 3.2e-29 100.6 0.0 3.4e-15 55.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.11 CDJ91302.1 - 3.3e-06 27.2 0.0 7.6e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 NOPS (NUC059) domain RRM_7 PF16367.5 CDJ91302.1 - 0.016 15.3 0.0 0.083 13.0 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif B9-C2 PF07162.11 CDJ91304.1 - 3.3e-25 89.2 0.0 5.7e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein SIR2 PF02146.17 CDJ91305.1 - 1.7e-37 129.0 0.0 3.4e-20 72.7 0.0 2.3 1 1 1 2 2 2 2 Sir2 family HTH_24 PF13412.6 CDJ91305.1 - 0.17 11.5 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF4199 PF13858.6 CDJ91306.1 - 0.055 13.9 0.1 0.055 13.9 0.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF4199) DUF2157 PF09925.9 CDJ91306.1 - 0.059 13.2 0.1 0.25 11.1 0.0 2.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) PBECR4 PF18813.1 CDJ91306.1 - 0.14 12.3 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease4 Na_H_Exchanger PF00999.21 CDJ91306.1 - 0.32 9.7 5.8 0.27 10.0 0.3 2.4 3 0 0 3 3 3 0 Sodium/hydrogen exchanger family DUF3043 PF11241.8 CDJ91307.1 - 1.7 8.6 4.1 1.3 9.0 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) RNase_PH PF01138.21 CDJ91308.1 - 3.1e-12 47.1 0.0 7e-12 46.0 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CDJ91308.1 - 0.014 15.4 0.0 0.05 13.6 0.0 1.9 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 GBP_PSP PF02425.15 CDJ91308.1 - 1 9.1 2.9 11 5.8 0.2 2.5 2 0 0 2 2 2 0 Paralytic/GBP/PSP peptide DNA_pol_A_exo1 PF01612.20 CDJ91309.1 - 1.1e-41 142.5 0.1 2.4e-41 141.4 0.1 1.6 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 CDJ91309.1 - 3e-13 49.5 0.0 9.8e-13 47.9 0.0 2.0 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.12 CDJ91309.1 - 9e-09 35.9 0.1 4.5e-08 33.7 0.0 2.3 2 0 0 2 2 2 1 PMC2NT (NUC016) domain Glyco_transf_22 PF03901.17 CDJ91310.1 - 4.3e-96 322.7 34.0 5.5e-96 322.3 34.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF648 PF04890.13 CDJ91310.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) MRP-S22 PF10245.9 CDJ91311.1 - 1.6e-88 296.5 0.1 2.7e-88 295.8 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S22 HALZ PF02183.18 CDJ91311.1 - 0.18 12.1 3.7 0.56 10.5 1.8 2.9 2 1 0 2 2 2 0 Homeobox associated leucine zipper Shisa PF13908.6 CDJ91312.1 - 0.0045 17.3 1.9 0.0045 17.3 1.9 2.4 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator Amnionless PF14828.6 CDJ91312.1 - 0.0098 14.8 0.2 0.011 14.7 0.2 1.2 1 0 0 1 1 1 1 Amnionless Neur_chan_memb PF02932.16 CDJ91312.1 - 0.014 15.4 3.7 0.59 10.1 0.1 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 CDJ91312.1 - 0.03 13.5 0.2 0.05 12.8 0.2 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter TRP PF06011.12 CDJ91312.1 - 0.032 13.0 1.6 0.04 12.6 1.6 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel TarH PF02203.15 CDJ91312.1 - 0.047 13.6 0.5 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Tar ligand binding domain homologue TMEM132D_C PF15706.5 CDJ91312.1 - 0.064 13.0 0.0 0.2 11.5 0.0 1.9 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Orf78 PF06024.12 CDJ91312.1 - 0.071 13.4 0.2 0.41 11.0 0.0 2.2 1 1 1 2 2 2 0 Orf78 (ac78) SID-1_RNA_chan PF13965.6 CDJ91312.1 - 0.36 9.2 4.4 0.25 9.7 0.1 1.9 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 Comm PF15957.5 CDJ91312.1 - 0.45 10.9 2.8 0.67 10.3 0.0 2.4 2 1 0 2 2 2 0 Commissureless RIFIN PF02009.16 CDJ91312.1 - 0.8 9.5 12.7 3.9 7.3 12.8 1.8 1 1 0 1 1 1 0 Rifin Hid1 PF12722.7 CDJ91312.1 - 1.3 7.0 11.6 2.2 6.3 11.6 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SabA_adhesion PF18304.1 CDJ91312.1 - 4.5 6.4 12.7 6.5 5.9 12.7 1.2 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain DUF4834 PF16118.5 CDJ91312.1 - 5.1 8.1 16.5 2.3 9.3 0.1 3.3 2 1 0 2 2 1 0 Domain of unknown function (DUF4834) MMM1 PF10296.9 CDJ91312.1 - 9.5 5.2 7.2 2 7.4 0.0 2.4 2 1 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 DUF1907 PF08925.11 CDJ91313.1 - 0.0013 18.2 0.9 0.0021 17.5 0.9 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) DUF3837 PF12939.7 CDJ91313.1 - 0.055 13.9 0.7 0.31 11.4 0.0 2.6 3 1 1 4 4 4 0 Domain of unknown function (DUF3837) AAA PF00004.29 CDJ91314.1 - 1.2e-38 132.5 0.0 2.2e-37 128.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ91314.1 - 9e-07 29.4 1.3 3.3e-06 27.6 0.3 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CDJ91314.1 - 1.5e-06 28.1 0.0 4.3e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 CDJ91314.1 - 1.9e-06 27.9 0.3 0.015 15.3 0.0 2.7 1 1 1 2 2 2 2 NACHT domain AAA_25 PF13481.6 CDJ91314.1 - 8.5e-06 25.5 0.4 0.0006 19.4 0.0 2.3 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 CDJ91314.1 - 1.3e-05 24.6 0.0 2.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 CDJ91314.1 - 2.4e-05 24.4 0.2 0.00022 21.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDJ91314.1 - 2.6e-05 24.5 2.5 0.043 14.1 0.0 2.8 2 1 1 3 3 2 2 AAA domain DUF815 PF05673.13 CDJ91314.1 - 0.00017 20.9 0.0 0.00027 20.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 CDJ91314.1 - 0.00024 20.6 0.0 0.00071 19.1 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 CDJ91314.1 - 0.00029 21.2 0.0 0.00089 19.6 0.0 1.9 1 1 0 1 1 1 1 RNA helicase AAA_lid_3 PF17862.1 CDJ91314.1 - 0.00081 19.2 0.0 0.0022 17.7 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_18 PF13238.6 CDJ91314.1 - 0.0011 19.5 0.0 0.0089 16.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CDJ91314.1 - 0.0013 18.8 0.0 0.0031 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CDJ91314.1 - 0.0017 18.5 0.0 0.0035 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 CDJ91314.1 - 0.0019 17.9 0.0 0.0067 16.2 0.0 1.8 1 1 0 1 1 1 1 IstB-like ATP binding protein ATPase_2 PF01637.18 CDJ91314.1 - 0.0031 17.5 0.3 0.033 14.1 0.0 2.7 2 2 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 CDJ91314.1 - 0.0036 17.5 0.0 0.0094 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 CDJ91314.1 - 0.0043 16.2 0.0 0.0095 15.1 0.0 1.5 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 CDJ91314.1 - 0.0051 17.3 0.0 0.015 15.9 0.0 1.8 2 0 0 2 2 1 1 ABC transporter KAP_NTPase PF07693.14 CDJ91314.1 - 0.0056 15.9 0.3 0.67 9.1 0.0 2.5 1 1 1 2 2 2 1 KAP family P-loop domain Mg_chelatase PF01078.21 CDJ91314.1 - 0.0062 15.9 0.1 0.041 13.3 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI KTI12 PF08433.10 CDJ91314.1 - 0.016 14.6 0.0 0.062 12.7 0.0 1.9 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_19 PF13245.6 CDJ91314.1 - 0.019 15.3 0.0 0.062 13.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 CDJ91314.1 - 0.019 14.1 0.0 0.033 13.3 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_24 PF13479.6 CDJ91314.1 - 0.023 14.4 0.0 0.069 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CDJ91314.1 - 0.026 15.0 0.0 0.076 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 CDJ91314.1 - 0.027 14.3 0.0 0.19 11.6 0.0 2.2 1 1 0 1 1 1 0 Bacterial dnaA protein TsaE PF02367.17 CDJ91314.1 - 0.027 14.5 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 CDJ91314.1 - 0.029 14.1 0.0 0.12 12.1 0.0 2.0 2 1 1 3 3 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 CDJ91314.1 - 0.036 13.9 0.1 0.15 11.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CDJ91314.1 - 0.051 12.8 0.0 0.15 11.2 0.0 1.9 1 1 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 CDJ91314.1 - 0.067 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.15 CDJ91314.1 - 0.079 12.9 0.0 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.9 CDJ91314.1 - 0.085 12.1 0.0 0.23 10.7 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RsgA_GTPase PF03193.16 CDJ91314.1 - 0.098 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 CDJ91314.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain Ish1 PF10281.9 CDJ91314.1 - 0.13 12.6 0.4 0.42 10.9 0.4 2.0 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein DUF3452 PF11934.8 CDJ91315.1 - 0.0074 15.8 0.1 0.17 11.4 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3452) CRIM PF16978.5 CDJ91316.1 - 1.3e-17 64.3 0.0 4.5e-17 62.5 0.0 2.0 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain cwf21 PF08312.12 CDJ91316.1 - 4.8e-11 42.6 1.6 4.8e-11 42.6 1.6 2.9 2 0 0 2 2 2 1 cwf21 domain MIP PF00230.20 CDJ91317.1 - 1.3e-14 54.4 7.9 2.7e-14 53.4 7.9 1.5 1 1 0 1 1 1 1 Major intrinsic protein CclA_1 PF16942.5 CDJ91317.1 - 0.46 10.8 7.0 0.71 10.2 2.2 2.4 2 0 0 2 2 2 0 Putative cyclic bacteriocin UBA_4 PF14555.6 CDJ91318.1 - 1.9e-10 40.4 0.1 5.2e-10 39.0 0.1 1.8 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 CDJ91318.1 - 1.2e-05 25.4 0.1 3.3e-05 24.0 0.1 1.8 1 0 0 1 1 1 1 UBX domain ING PF12998.7 CDJ91319.1 - 6.5e-10 39.5 1.6 6.5e-10 39.5 1.6 2.0 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CDJ91319.1 - 1.3e-05 25.0 12.5 2.8e-05 23.9 12.5 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CDJ91319.1 - 0.1 12.8 3.4 0.39 11.0 3.4 2.0 1 0 0 1 1 1 0 PHD-like zinc-binding domain YafO_toxin PF13957.6 CDJ91319.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Toxin YafO, type II toxin-antitoxin system DUF4509 PF14970.6 CDJ91320.1 - 0.014 15.4 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) Ldl_recept_b PF00058.17 CDJ91321.1 - 1.6e-24 86.1 7.6 5.7e-07 29.9 0.0 5.9 6 0 0 6 6 6 5 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 CDJ91321.1 - 8.8e-12 45.1 35.6 1.8e-07 31.3 10.2 3.8 3 0 0 3 3 3 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 CDJ91321.1 - 7.6e-08 32.4 9.3 7.6e-08 32.4 9.3 4.1 4 0 0 4 4 4 1 Calcium-binding EGF domain cEGF PF12662.7 CDJ91321.1 - 4.1e-07 29.8 21.3 0.0027 17.6 2.3 3.9 3 0 0 3 3 3 3 Complement Clr-like EGF-like hEGF PF12661.7 CDJ91321.1 - 0.0011 19.5 3.3 0.0011 19.5 3.3 3.7 3 0 0 3 3 3 1 Human growth factor-like EGF DUF5050 PF16472.5 CDJ91321.1 - 0.0032 16.7 0.0 0.023 14.0 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF5050) CAP PF00188.26 CDJ91322.1 - 5.1e-17 62.9 5.4 7.2e-17 62.4 5.4 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family RVT_1 PF00078.27 CDJ91323.1 - 1.5e-14 54.1 0.0 3e-14 53.1 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) ANTH PF07651.16 CDJ91325.1 - 6.1e-69 232.1 1.3 9.4e-69 231.5 0.0 2.0 2 0 0 2 2 2 1 ANTH domain I_LWEQ PF01608.17 CDJ91325.1 - 6.6e-52 175.8 14.1 6.6e-52 175.8 14.1 5.3 3 2 2 6 6 6 1 I/LWEQ domain Baculo_gp64 PF03273.13 CDJ91325.1 - 0.62 8.8 3.0 0.3 9.9 0.4 1.6 2 0 0 2 2 2 0 Baculovirus gp64 envelope glycoprotein family DUF2999 PF11212.8 CDJ91325.1 - 2.1 8.7 9.6 0.26 11.6 2.4 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2999) RVT_1 PF00078.27 CDJ91326.1 - 9.1e-32 110.4 0.0 1e-31 110.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 2-oxogl_dehyd_N PF16078.5 CDJ91327.1 - 0.13 11.9 0.0 25 4.5 0.0 2.6 2 0 0 2 2 2 0 2-oxoglutarate dehydrogenase N-terminus Phage_XkdX PF09693.10 CDJ91327.1 - 0.22 11.6 2.1 19 5.4 0.1 3.5 3 0 0 3 3 3 0 Phage uncharacterised protein (Phage_XkdX) Metal_resist PF13801.6 CDJ91329.1 - 0.019 15.2 1.8 3.1 8.0 0.3 3.1 2 0 0 2 2 2 0 Heavy-metal resistance Ribosomal_L38e PF01781.18 CDJ91331.1 - 1.1e-34 118.3 3.9 1.2e-34 118.2 3.9 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Neur_chan_LBD PF02931.23 CDJ91333.1 - 1.1e-21 77.3 0.2 2.1e-21 76.4 0.1 1.5 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain DUF1794 PF08768.11 CDJ91334.1 - 2.6e-08 34.0 0.0 3.9e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) ShK PF01549.24 CDJ91334.1 - 1.1e-07 32.3 6.6 1.7e-07 31.7 6.6 1.3 1 0 0 1 1 1 1 ShK domain-like HTH_Tnp_Tc5 PF03221.16 CDJ91334.1 - 0.037 14.0 0.1 0.078 13.0 0.1 1.5 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain bZIP_Maf PF03131.17 CDJ91336.1 - 3.9e-18 65.7 8.0 5.9e-18 65.2 8.0 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor Luteo_PO PF04662.13 CDJ91336.1 - 0.0022 17.7 0.5 0.0032 17.2 0.5 1.3 1 0 0 1 1 1 1 Luteovirus P0 protein bZIP_1 PF00170.21 CDJ91336.1 - 0.013 15.5 4.3 0.024 14.7 4.3 1.3 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 CDJ91336.1 - 0.03 14.4 3.5 0.03 14.4 3.5 1.9 1 1 1 2 2 2 0 Basic region leucine zipper C_Hendra PF16821.5 CDJ91336.1 - 0.055 13.4 0.7 0.055 13.4 0.7 2.0 1 1 1 2 2 2 0 C protein from hendra and measles viruses CAMP_factor PF07373.11 CDJ91336.1 - 0.084 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 CAMP factor (Cfa) Prominin PF05478.11 CDJ91336.1 - 0.4 8.6 4.1 0.54 8.2 1.8 1.7 1 1 1 2 2 2 0 Prominin Coat_F PF07875.12 CDJ91336.1 - 3.8 7.8 8.6 3.3 8.0 0.2 2.8 3 0 0 3 3 3 0 Coat F domain Aldedh PF00171.22 CDJ91337.1 - 3.1e-67 227.1 0.0 3.4e-67 226.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RhoGAP PF00620.27 CDJ91338.1 - 3.1e-46 156.9 1.4 4.3e-46 156.5 0.7 1.6 1 1 1 2 2 2 1 RhoGAP domain C1_1 PF00130.22 CDJ91338.1 - 7.2e-14 51.4 7.0 1.6e-13 50.3 7.0 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH2 PF00017.24 CDJ91338.1 - 1.8e-12 47.1 0.0 3.7e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 SH2 domain zf-RING-like PF08746.11 CDJ91338.1 - 0.037 14.3 5.4 0.088 13.1 5.4 1.6 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 CDJ91338.1 - 0.074 12.9 4.0 0.16 11.9 4.0 1.6 1 0 0 1 1 1 0 PHD-finger Acetyltransf_11 PF13720.6 CDJ91338.1 - 0.081 13.4 0.0 0.19 12.2 0.0 1.7 1 1 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 CarboxypepD_reg PF13620.6 CDJ91339.1 - 7.7e-41 138.3 26.0 4e-06 27.0 0.8 11.7 10 2 1 11 11 11 8 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 CDJ91339.1 - 2.1e-20 73.0 4.3 0.0025 18.0 0.4 8.0 8 0 0 8 8 8 5 SdrD B-like domain CarbopepD_reg_2 PF13715.6 CDJ91339.1 - 3.6e-11 42.9 10.8 0.00016 21.6 0.2 8.0 8 2 1 9 9 9 2 CarboxypepD_reg-like domain SpaA PF17802.1 CDJ91339.1 - 4.5e-07 30.1 9.8 1 9.7 0.1 6.9 5 3 2 7 7 7 2 Prealbumin-like fold domain DUF2012 PF09430.10 CDJ91339.1 - 2.7e-06 27.5 0.4 3.3 7.8 0.0 7.0 4 3 1 7 7 7 1 Protein of unknown function (DUF2012) fn3_3 PF14686.6 CDJ91339.1 - 8.6e-05 22.2 3.3 8 6.3 0.0 7.8 9 0 0 9 9 9 1 Polysaccharide lyase family 4, domain II DUF4198 PF10670.9 CDJ91339.1 - 0.00011 22.6 0.7 0.022 15.1 0.0 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF4198) fn3 PF00041.21 CDJ91339.1 - 0.00072 19.9 0.4 1.8 8.9 0.0 3.3 2 0 0 2 2 2 2 Fibronectin type III domain DUF2846 PF11008.8 CDJ91339.1 - 0.0012 18.8 0.0 17 5.5 0.0 5.4 5 0 0 5 5 5 0 Protein of unknown function (DUF2846) MetallophosN PF16371.5 CDJ91339.1 - 0.0032 17.7 5.2 0.022 15.0 0.4 4.7 5 1 1 6 6 6 1 N terminal of Calcineurin-like phosphoesterase phage_tail_N PF08400.10 CDJ91339.1 - 0.01 15.8 1.2 0.24 11.4 0.5 3.5 3 0 0 3 3 3 0 Prophage tail fibre N-terminal Y_Y_Y PF07495.13 CDJ91339.1 - 0.012 15.5 0.5 19 5.3 0.0 4.5 4 0 0 4 4 4 0 Y_Y_Y domain SCP2 PF02036.17 CDJ91341.1 - 3e-21 75.8 1.0 3.4e-21 75.6 1.0 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 CDJ91341.1 - 4.5e-05 23.7 0.4 5.4e-05 23.5 0.4 1.3 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal DAGK_cat PF00781.24 CDJ91341.1 - 0.041 13.5 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain SCP2 PF02036.17 CDJ91342.1 - 1.2e-14 54.6 0.0 1.5e-14 54.3 0.0 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 CDJ91342.1 - 0.0027 18.0 0.0 0.046 14.0 0.0 1.9 1 1 1 2 2 2 1 Alkyl sulfatase C-terminal ShK PF01549.24 CDJ91343.1 - 1.4e-19 70.3 53.4 3.5e-06 27.4 10.3 5.1 5 0 0 5 5 5 4 ShK domain-like Collagen PF01391.18 CDJ91343.1 - 4.4e-05 23.1 15.6 7.3e-05 22.4 15.6 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) ShK PF01549.24 CDJ91344.1 - 1.3e-19 70.4 54.9 4.2e-07 30.4 5.7 5.2 5 1 0 5 5 5 4 ShK domain-like ShK PF01549.24 CDJ91345.1 - 5.8e-13 49.1 37.9 3e-06 27.7 10.5 4.2 4 1 0 4 4 4 3 ShK domain-like CAP PF00188.26 CDJ91346.1 - 4e-15 56.8 1.3 4e-15 56.8 1.3 2.3 2 0 0 2 2 2 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ91346.1 - 5.5 7.3 11.6 0.054 13.8 1.5 2.8 2 1 1 3 3 3 0 Ancylostoma-associated secreted protein related DUF5354 PF17305.2 CDJ91347.1 - 2.1e-07 31.2 0.1 2.7e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5354) DUF5354 PF17305.2 CDJ91349.1 - 4.8e-15 55.9 0.2 6.2e-15 55.5 0.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5354) RVT_1 PF00078.27 CDJ91351.1 - 4.8e-09 36.0 0.0 7.3e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MoeA_N PF03453.17 CDJ91353.1 - 9.1e-39 132.7 1.4 1.7e-38 131.8 1.4 1.5 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) Pinin_SDK_memA PF04696.13 CDJ91353.1 - 2.9e-26 92.0 21.8 2.9e-26 92.0 21.8 2.7 1 1 2 3 3 3 1 pinin/SDK/memA/ protein conserved region MoCF_biosynth PF00994.24 CDJ91353.1 - 4.9e-23 81.4 0.0 1.2e-22 80.1 0.0 1.7 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 CDJ91353.1 - 2.8e-10 40.2 0.0 1.4e-09 38.0 0.0 2.3 3 0 0 3 3 3 1 MoeA C-terminal region (domain IV) Pinin_SDK_N PF04697.13 CDJ91353.1 - 0.0044 17.7 1.6 0.0044 17.7 1.6 2.7 2 0 0 2 2 2 1 pinin/SDK conserved region Ion_trans PF00520.31 CDJ91354.1 - 2.3e-43 148.2 9.3 3e-43 147.8 9.3 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 CDJ91354.1 - 1.9e-28 98.7 0.0 3.7e-28 97.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 CDJ91354.1 - 1.8e-13 50.2 3.5 1.8e-13 50.2 3.5 2.2 2 0 0 2 2 2 1 Ion channel AmpE PF17113.5 CDJ91354.1 - 0.047 13.0 0.4 0.081 12.2 0.4 1.3 1 0 0 1 1 1 0 Regulatory signalling modulator protein AmpE BTB_3 PF16017.5 CDJ91354.1 - 0.094 12.8 0.0 0.54 10.4 0.0 2.3 2 1 0 2 2 2 0 BTB/POZ domain DUF202 PF02656.15 CDJ91354.1 - 0.82 10.2 4.7 33 5.0 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF202) TSP_1 PF00090.19 CDJ91355.1 - 9.9e-06 25.7 4.2 1.7e-05 24.9 4.2 1.4 1 0 0 1 1 1 1 Thrombospondin type 1 domain ETRAMP PF09716.10 CDJ91357.1 - 0.19 11.8 6.3 0.28 11.3 6.2 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) TAP35_44 PF07265.11 CDJ91357.1 - 0.21 11.6 1.4 0.29 11.2 1.4 1.2 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 Pkinase_Tyr PF07714.17 CDJ91358.1 - 1.1e-87 293.6 0.0 1.7e-87 293.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ91358.1 - 8.2e-38 130.3 0.0 3.1e-36 125.1 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Na_Ca_ex PF01699.24 CDJ91358.1 - 0.027 14.4 0.1 0.048 13.6 0.1 1.3 1 0 0 1 1 1 0 Sodium/calcium exchanger protein ETRAMP PF09716.10 CDJ91358.1 - 0.059 13.4 0.0 0.099 12.7 0.0 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF842 PF05811.13 CDJ91358.1 - 0.072 12.8 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) LapA_dom PF06305.11 CDJ91358.1 - 0.13 12.1 0.4 0.26 11.1 0.4 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Adeno_E3_CR2 PF02439.15 CDJ91358.1 - 0.14 12.0 3.4 0.26 11.1 3.4 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TMEM154 PF15102.6 CDJ91358.1 - 0.15 12.0 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family Collagen PF01391.18 CDJ91359.1 - 1.2e-27 95.4 83.2 1.4e-09 37.5 22.6 4.1 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ91359.1 - 2.2e-13 50.0 0.5 2.8e-13 49.7 0.5 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain DUF4834 PF16118.5 CDJ91361.1 - 0.00037 21.4 0.1 0.0015 19.5 0.0 2.1 2 0 0 2 2 1 1 Domain of unknown function (DUF4834) MAP17 PF15807.5 CDJ91361.1 - 0.0018 18.5 0.0 0.0044 17.2 0.0 1.5 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Podoplanin PF05808.11 CDJ91361.1 - 0.0019 18.3 0.7 0.0019 18.3 0.7 1.8 2 0 0 2 2 2 1 Podoplanin SpoIIIAH PF12685.7 CDJ91361.1 - 0.0033 17.3 0.2 0.0033 17.3 0.2 1.7 2 0 0 2 2 2 1 SpoIIIAH-like protein Myc_target_1 PF15179.6 CDJ91361.1 - 0.0053 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Myc target protein 1 EphA2_TM PF14575.6 CDJ91361.1 - 0.0062 17.4 0.5 0.022 15.7 0.5 2.0 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain FAM176 PF14851.6 CDJ91361.1 - 0.0064 16.2 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 FAM176 family SIT PF15330.6 CDJ91361.1 - 0.014 15.9 0.0 0.051 14.0 0.0 2.0 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT LapA_dom PF06305.11 CDJ91361.1 - 0.017 14.9 0.9 0.044 13.6 0.9 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Zip PF02535.22 CDJ91361.1 - 0.019 14.2 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter UPF0239 PF06783.11 CDJ91361.1 - 0.029 14.6 2.6 0.088 13.0 2.4 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0239) Herpes_gE PF02480.16 CDJ91361.1 - 0.042 12.6 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Neur_chan_memb PF02932.16 CDJ91361.1 - 0.088 12.9 0.2 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Serinc PF03348.15 CDJ91361.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) V_ATPase_I PF01496.19 CDJ91361.1 - 0.13 10.2 0.2 0.2 9.6 0.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMEM154 PF15102.6 CDJ91361.1 - 0.2 11.6 1.1 0.53 10.2 1.1 1.9 1 1 0 1 1 1 0 TMEM154 protein family Connexin PF00029.19 CDJ91361.1 - 0.33 10.7 1.6 0.6 9.8 1.6 1.3 1 0 0 1 1 1 0 Connexin DUF2615 PF11027.8 CDJ91361.1 - 0.54 10.4 0.0 0.54 10.4 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2615) Stevor PF17410.2 CDJ91361.1 - 4.4 6.8 6.5 0.97 8.9 2.6 1.9 2 1 0 2 2 2 0 Subtelomeric Variable Open Reading frame NPR3 PF03666.13 CDJ91361.1 - 6.9 5.3 11.0 10 4.8 11.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ank_2 PF12796.7 CDJ91362.1 - 2.8e-11 43.9 0.0 0.00014 22.4 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDJ91362.1 - 4e-08 32.9 0.6 0.54 11.0 0.0 6.2 6 0 0 6 6 6 1 Ankyrin repeat RsdA_SigD_bd PF16751.5 CDJ91362.1 - 0.0057 16.9 1.2 0.014 15.6 0.1 2.2 2 0 0 2 2 2 1 Anti-sigma-D factor RsdA to sigma factor binding region Ank_5 PF13857.6 CDJ91362.1 - 0.013 15.8 0.0 0.42 11.0 0.0 3.1 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.30 CDJ91362.1 - 0.043 14.3 0.2 72 4.1 0.1 3.9 3 0 0 3 3 3 0 Ankyrin repeat AT_hook PF02178.19 CDJ91362.1 - 0.18 11.8 3.3 1 9.4 3.3 2.4 1 0 0 1 1 1 0 AT hook motif DUF3993 PF13158.6 CDJ91363.1 - 0.082 13.1 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) ASPRs PF17641.2 CDJ91363.1 - 0.088 13.1 0.1 0.12 12.7 0.1 1.1 1 0 0 1 1 1 0 Ancylostoma-associated secreted protein related 60KD_IMP PF02096.20 CDJ91363.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein RPN2_C PF18004.1 CDJ91364.1 - 6.7 6.6 24.8 8.5 6.3 24.8 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Pkinase PF00069.25 CDJ91367.1 - 7.9e-68 228.7 0.0 9.8e-68 228.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ91367.1 - 3.1e-51 174.2 0.0 4.3e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CDJ91367.1 - 1.5e-12 47.6 0.0 3.7e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 CDJ91367.1 - 0.00049 19.5 0.1 0.00081 18.8 0.1 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CDJ91367.1 - 0.015 15.3 0.1 0.68 9.8 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF5473 PF17567.2 CDJ91367.1 - 0.02 15.2 1.0 0.11 12.8 0.6 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5473) Kdo PF06293.14 CDJ91367.1 - 0.07 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAN_3 PF08277.12 CDJ91368.1 - 0.11 12.3 0.9 0.18 11.6 0.9 1.4 1 0 0 1 1 1 0 PAN-like domain WD40 PF00400.32 CDJ91370.1 - 4.3e-21 74.8 13.4 0.0011 19.7 0.1 8.2 10 0 0 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ91370.1 - 2.1e-08 34.4 0.0 1.1 9.6 0.0 5.4 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDJ91370.1 - 2.1e-05 24.5 0.0 0.0033 17.3 0.0 3.3 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A MRI PF15325.6 CDJ91370.1 - 0.033 15.3 1.3 0.085 13.9 1.3 1.7 1 0 0 1 1 1 0 Modulator of retrovirus infection DTHCT PF08070.11 CDJ91370.1 - 0.32 11.7 3.1 0.94 10.2 3.1 1.8 1 1 0 1 1 1 0 DTHCT (NUC029) region PX PF00787.24 CDJ91371.1 - 2.7e-18 66.0 0.4 6.4e-18 64.8 0.4 1.6 1 0 0 1 1 1 1 PX domain Zn_ribbon_recom PF13408.6 CDJ91371.1 - 0.067 13.7 3.6 0.14 12.7 3.6 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain DUF3268 PF11672.8 CDJ91371.1 - 0.08 13.3 0.8 0.21 11.9 0.8 1.7 1 0 0 1 1 1 0 zinc-finger-containing domain Zn_ribbon_SprT PF17283.2 CDJ91371.1 - 1.5 8.8 6.8 2.1 8.4 0.9 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Transposase_1 PF01359.18 CDJ91373.1 - 3.8e-30 103.5 0.4 3.8e-30 103.5 0.4 1.8 2 0 0 2 2 2 1 Transposase (partial DDE domain) DDE_3 PF13358.6 CDJ91373.1 - 5.2e-05 23.0 0.0 7.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease ASPRs PF17641.2 CDJ91374.1 - 0.067 13.5 0.1 0.088 13.1 0.1 1.2 1 0 0 1 1 1 0 Ancylostoma-associated secreted protein related DUF3270 PF11674.8 CDJ91375.1 - 0.1 12.8 0.5 0.11 12.6 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) BatA PF07584.11 CDJ91375.1 - 0.11 12.8 0.0 0.12 12.8 0.0 1.1 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Orf78 PF06024.12 CDJ91375.1 - 0.11 12.7 2.0 0.11 12.8 2.0 1.1 1 0 0 1 1 1 0 Orf78 (ac78) PsbN PF02468.15 CDJ91375.1 - 0.13 12.1 0.4 0.15 11.9 0.4 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) Chordopox_A13L PF05961.11 CDJ91375.1 - 0.16 12.2 2.5 0.17 12.1 2.5 1.1 1 0 0 1 1 1 0 Chordopoxvirus A13L protein FixQ PF05545.11 CDJ91375.1 - 0.49 10.4 2.9 1 9.4 2.9 1.7 1 1 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Coat_F PF07875.12 CDJ91376.1 - 0.56 10.5 7.9 2.5 8.4 0.6 3.9 3 0 0 3 3 3 0 Coat F domain Coa1 PF08695.10 CDJ91378.1 - 8.3e-08 32.0 0.0 9.8e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Spore_YtrH PF14034.6 CDJ91378.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.7 1 1 1 2 2 2 0 Sporulation protein YtrH PCI PF01399.27 CDJ91379.1 - 1.2e-07 32.2 0.2 3.2e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 PCI domain DUF4061 PF13270.6 CDJ91380.1 - 2.8e-07 30.7 4.1 2.8e-07 30.7 4.1 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4061) GCIP PF13324.6 CDJ91380.1 - 0.53 9.8 6.5 0.029 14.0 0.9 1.6 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting BSD PF03909.17 CDJ91381.1 - 9.6e-37 124.8 1.2 1.6e-17 63.2 0.1 3.7 3 0 0 3 3 3 3 BSD domain PH_TFIIH PF08567.11 CDJ91381.1 - 4.5e-16 58.9 0.2 2.6e-15 56.5 0.0 2.3 3 0 0 3 3 3 1 TFIIH p62 subunit, N-terminal domain CPT_N PF16484.5 CDJ91381.1 - 0.0018 18.2 0.0 4 7.5 0.0 2.7 2 0 0 2 2 2 2 Carnitine O-palmitoyltransferase N-terminus RNA_pol_Rpb1_5 PF04998.17 CDJ91381.1 - 0.0086 15.5 2.7 1.3 8.4 1.1 2.3 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 5 SLT_2 PF13406.6 CDJ91381.1 - 0.02 14.2 1.1 2.4 7.3 0.2 2.5 2 0 0 2 2 2 0 Transglycosylase SLT domain PAPS_reduct PF01507.19 CDJ91381.1 - 0.07 13.2 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Vir_act_alpha_C PF10400.9 CDJ91381.1 - 0.41 11.3 3.9 0.56 10.9 1.2 2.6 3 0 0 3 3 3 0 Virulence activator alpha C-term HLH PF00010.26 CDJ91382.1 - 1.6e-17 63.2 2.5 2.9e-17 62.4 2.5 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Cnn_1N PF07989.11 CDJ91382.1 - 0.025 14.7 0.1 0.053 13.7 0.1 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 HALZ PF02183.18 CDJ91382.1 - 0.15 12.3 0.3 0.28 11.5 0.3 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper DNA_pol_phi PF04931.13 CDJ91383.1 - 1.2e-26 93.1 22.8 4.9e-24 84.5 15.5 2.6 2 1 0 3 3 3 2 DNA polymerase phi SDA1 PF05285.12 CDJ91383.1 - 0.2 11.1 8.8 0.32 10.4 8.8 1.2 1 0 0 1 1 1 0 SDA1 ParcG PF10274.9 CDJ91383.1 - 0.26 11.4 1.7 7.8 6.6 0.1 2.7 2 0 0 2 2 2 0 Parkin co-regulated protein TFIIF_alpha PF05793.12 CDJ91383.1 - 2.1 6.8 16.2 3.5 6.1 16.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RVT_1 PF00078.27 CDJ91384.1 - 4.5e-12 46.0 0.0 6.2e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MCPVI PF02993.14 CDJ91385.1 - 0.095 12.5 1.3 0.16 11.7 1.3 1.4 1 0 0 1 1 1 0 Minor capsid protein VI SHOCT PF09851.9 CDJ91385.1 - 0.33 10.8 3.2 0.38 10.6 1.0 2.3 2 0 0 2 2 2 0 Short C-terminal domain FAD_binding_1 PF00667.20 CDJ91386.1 - 2.2e-67 226.9 0.0 2.9e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CDJ91386.1 - 2.6e-34 118.5 0.2 4.4e-34 117.7 0.2 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CDJ91386.1 - 5.5e-11 43.1 0.0 2.2e-10 41.1 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Nup188 PF10487.9 CDJ91386.1 - 0.26 9.2 0.0 0.34 8.8 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 EMP24_GP25L PF01105.24 CDJ91387.1 - 7.2e-20 71.7 2.0 7.8e-20 71.6 2.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Lipase_chap PF03280.14 CDJ91388.1 - 0.011 15.7 18.6 0.44 10.5 8.1 2.1 1 1 1 2 2 2 0 Proteobacterial lipase chaperone protein FA_FANCE PF11510.8 CDJ91388.1 - 0.076 12.4 0.0 0.099 12.0 0.0 1.1 1 0 0 1 1 1 0 Fanconi Anaemia group E protein FANCE DUF148 PF02520.17 CDJ91388.1 - 0.13 12.4 4.8 0.18 11.9 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF148 DUF2070 PF09843.9 CDJ91389.1 - 0.051 11.9 8.2 0.078 11.3 8.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HemY_N PF07219.13 CDJ91389.1 - 1.4 9.1 5.5 0.63 10.3 0.4 2.7 2 1 1 3 3 3 0 HemY protein N-terminus TMEM144 PF07857.12 CDJ91390.1 - 6.8e-121 403.3 8.2 8e-121 403.1 8.2 1.0 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 CDJ91390.1 - 6.9e-10 38.7 2.9 6.9e-10 38.7 2.9 2.6 2 1 0 2 2 2 2 Sugar transport protein DUF5367 PF17329.2 CDJ91390.1 - 1.8 8.8 7.4 0.8 9.9 1.3 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5367) Vma12 PF11712.8 CDJ91390.1 - 1.9 8.6 4.8 0.78 9.8 0.1 2.5 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DotA PF11388.8 CDJ91391.1 - 0.064 13.5 0.6 8.9 6.6 0.1 2.2 2 0 0 2 2 2 0 Phagosome trafficking protein DotA zf-B_box PF00643.24 CDJ91392.1 - 8.5e-10 38.6 13.4 6.6e-08 32.6 6.1 3.6 3 0 0 3 3 3 2 B-box zinc finger AIP3 PF03915.13 CDJ91392.1 - 5.2e-09 35.7 3.3 5.2e-09 35.7 3.3 2.6 2 1 0 2 2 2 1 Actin interacting protein 3 Y_phosphatase PF00102.27 CDJ91394.1 - 6.3e-34 117.6 0.0 1e-33 116.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Apolipoprotein PF01442.18 CDJ91394.1 - 2.7e-13 50.2 99.6 0.0092 15.9 19.4 9.1 2 2 6 8 8 8 7 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 CDJ91394.1 - 1.4e-09 38.4 159.5 0.0058 17.2 0.8 18.5 1 1 13 17 17 17 9 Bacterial protein of unknown function (DUF883) LEA_4 PF02987.16 CDJ91394.1 - 1.4e-05 25.1 17.4 0.00029 20.9 4.5 25.1 17 5 9 26 26 26 8 Late embryogenesis abundant protein ApoLp-III PF07464.11 CDJ91394.1 - 0.00053 20.1 93.9 0.44 10.6 6.8 12.0 1 1 11 14 14 14 7 Apolipophorin-III precursor (apoLp-III) ATP-synt_B PF00430.18 CDJ91394.1 - 0.006 16.7 1.1 0.006 16.7 1.1 12.6 3 1 8 11 11 11 2 ATP synthase B/B' CF(0) Globin PF00042.22 CDJ91395.1 - 1.2e-06 29.1 0.0 2.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Globin Med2 PF11214.8 CDJ91395.1 - 0.087 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit 2 adh_short PF00106.25 CDJ91396.1 - 8.1e-30 103.7 0.0 1e-28 100.2 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ91396.1 - 1.1e-19 71.0 0.0 1.5e-18 67.2 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ91396.1 - 1.2e-05 25.3 0.0 2.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDJ91396.1 - 0.00056 19.4 0.0 0.00078 19.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Gp-FAR-1 PF05823.12 CDJ91397.1 - 1.2e-19 71.2 0.2 1.5e-19 70.8 0.2 1.1 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) PIN_8 PF18476.1 CDJ91397.1 - 0.021 14.7 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 PIN like domain DUF1351 PF07083.11 CDJ91397.1 - 0.031 14.1 2.0 0.069 12.9 2.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1351) Uteroglobin PF01099.17 CDJ91397.1 - 0.033 14.5 0.7 0.76 10.1 0.0 2.8 2 1 0 2 2 2 0 Uteroglobin family Baculo_PEP_C PF04513.12 CDJ91397.1 - 0.043 13.9 0.0 2.5 8.1 0.0 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus EDR1 PF14381.6 CDJ91397.1 - 0.063 13.0 0.0 0.17 11.6 0.0 1.7 1 1 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 DUF2748 PF10871.8 CDJ91397.1 - 0.1 11.2 0.1 0.12 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) adh_short_C2 PF13561.6 CDJ91400.1 - 9.6e-50 169.3 0.1 1.2e-49 169.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDJ91400.1 - 3.8e-44 150.5 0.3 5.1e-44 150.1 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase THF_DHG_CYH_C PF02882.19 CDJ91400.1 - 0.0013 18.1 0.2 0.003 16.9 0.1 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain KR PF08659.10 CDJ91400.1 - 0.0023 17.8 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 KR domain ApbA PF02558.16 CDJ91400.1 - 0.11 12.1 0.1 0.61 9.7 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA bZIP_2 PF07716.15 CDJ91401.1 - 0.048 13.7 3.2 0.15 12.2 3.2 1.9 1 0 0 1 1 1 0 Basic region leucine zipper CaMBD PF02888.16 CDJ91402.1 - 0.38 11.0 3.4 1.1 9.5 3.4 1.8 1 0 0 1 1 1 0 Calmodulin binding domain GOLD_2 PF13897.6 CDJ91403.1 - 2.6 8.5 4.8 6.6 7.2 1.1 2.4 2 1 0 2 2 2 0 Golgi-dynamics membrane-trafficking PAN_1 PF00024.26 CDJ91404.1 - 8.7e-11 41.6 1.4 1.2e-10 41.2 1.4 1.2 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 CDJ91404.1 - 4.8e-06 26.4 0.3 8.2e-06 25.6 0.3 1.4 1 0 0 1 1 1 1 PAN domain Arm PF00514.23 CDJ91405.1 - 2.5e-05 24.1 0.3 1.7 8.8 0.0 5.4 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CDJ91405.1 - 0.0034 17.7 0.1 0.41 11.1 0.0 3.5 3 1 1 4 4 4 1 HEAT repeats CDC14 PF08045.11 CDJ91405.1 - 0.019 14.1 1.9 0.89 8.6 0.1 2.6 2 0 0 2 2 2 0 Cell division control protein 14, SIN component HEAT PF02985.22 CDJ91405.1 - 0.1 12.9 0.0 1.1 9.7 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat COX7C PF02935.16 CDJ91406.1 - 1.2e-14 54.3 1.1 2e-14 53.6 1.1 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Fasciclin PF02469.22 CDJ91407.1 - 6.7e-24 84.5 0.4 1.1e-11 45.1 0.0 4.1 3 1 0 3 3 3 3 Fasciclin domain DUF5604 PF18300.1 CDJ91407.1 - 0.15 12.0 0.1 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5604) 2OG-FeII_Oxy_3 PF13640.6 CDJ91408.1 - 1.6e-11 44.9 0.0 3.7e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 CDJ91409.1 - 2.3e-11 44.4 0.0 3.7e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UreE_N PF02814.15 CDJ91409.1 - 0.027 14.0 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain Apyrase PF06079.11 CDJ91410.1 - 2.5e-106 355.2 0.5 3.1e-106 354.8 0.5 1.0 1 0 0 1 1 1 1 Apyrase PG_isomerase_N PF18353.1 CDJ91411.1 - 0.086 13.2 0.0 24 5.4 0.0 2.4 2 0 0 2 2 2 0 Phosphoglucose isomerase N-terminal domain DUF35_N PF12172.8 CDJ91411.1 - 0.4 10.6 3.5 17 5.4 0.3 2.6 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Glucosamine_iso PF01182.20 CDJ91414.1 - 8.5e-39 133.7 0.0 9.8e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase HAUS6_N PF14661.6 CDJ91416.1 - 5e-05 23.0 0.9 8.9e-05 22.2 0.9 1.4 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Jnk-SapK_ap_N PF09744.9 CDJ91416.1 - 9.2e-05 22.7 1.9 0.00018 21.8 1.9 1.5 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 ING PF12998.7 CDJ91416.1 - 0.0054 17.3 0.6 0.011 16.3 0.6 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding TMF_TATA_bd PF12325.8 CDJ91416.1 - 0.0058 16.8 3.8 0.012 15.9 3.8 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Atg14 PF10186.9 CDJ91416.1 - 0.011 14.8 3.4 0.014 14.5 3.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 CDJ91416.1 - 0.017 15.2 2.7 0.03 14.4 2.7 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Cnn_1N PF07989.11 CDJ91416.1 - 0.036 14.2 1.5 0.077 13.2 1.5 1.6 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 DUF1192 PF06698.11 CDJ91416.1 - 0.041 13.9 1.9 0.058 13.5 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) SPOUT_MTase_2 PF14419.6 CDJ91416.1 - 0.046 13.1 0.4 0.071 12.5 0.4 1.4 1 1 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP TMPIT PF07851.13 CDJ91416.1 - 0.05 12.8 3.2 0.071 12.3 3.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein Tho2 PF11262.8 CDJ91416.1 - 0.13 11.5 4.5 0.21 10.8 3.9 1.6 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DivIC PF04977.15 CDJ91416.1 - 0.15 11.8 1.3 0.33 10.8 1.0 1.7 1 1 0 1 1 1 0 Septum formation initiator EMP24_GP25L PF01105.24 CDJ91416.1 - 0.17 11.8 6.3 1.5 8.8 6.3 2.0 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF2203 PF09969.9 CDJ91416.1 - 0.32 11.7 2.6 0.26 12.0 0.9 1.7 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2203) DUF1515 PF07439.11 CDJ91416.1 - 0.45 10.6 3.2 0.76 9.8 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) IF-2B PF01008.17 CDJ91417.1 - 3.6e-68 229.8 0.2 5.1e-68 229.3 0.2 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family PS_pyruv_trans PF04230.13 CDJ91417.1 - 0.056 13.4 0.0 0.087 12.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase SMN PF06003.12 CDJ91417.1 - 0.37 10.0 2.7 0.71 9.1 2.7 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) KH_1 PF00013.29 CDJ91418.1 - 2.1e-06 27.4 0.7 4.3e-06 26.4 0.7 1.6 1 0 0 1 1 1 1 KH domain LtrA PF06772.11 CDJ91420.1 - 0.1 11.8 0.1 0.12 11.6 0.1 1.0 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) Neur_chan_LBD PF02931.23 CDJ91422.1 - 1.7e-34 119.2 1.5 2.1e-34 118.9 1.5 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.23 CDJ91423.1 - 6.2e-38 130.4 0.0 8e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ91423.1 - 3.7e-13 50.1 3.3 1.9e-11 44.5 1.6 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region HSP20 PF00011.21 CDJ91424.1 - 7.3e-20 71.0 0.2 1.2e-19 70.3 0.2 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Cupredoxin_1 PF13473.6 CDJ91424.1 - 0.041 14.0 0.1 0.058 13.5 0.1 1.2 1 0 0 1 1 1 0 Cupredoxin-like domain ArsA_HSP20 PF17886.1 CDJ91424.1 - 0.073 12.6 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 HSP20-like domain found in ArsA TUDOR PF00567.24 CDJ91425.1 - 3.1e-11 43.4 0.0 6.1e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Tudor domain RRM_1 PF00076.22 CDJ91425.1 - 1.6e-06 27.9 0.0 3.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ91425.1 - 0.034 13.7 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) STAR_dimer PF16544.5 CDJ91426.1 - 3e-17 61.9 0.8 6.3e-17 60.9 0.3 1.7 2 0 0 2 2 2 1 Homodimerisation region of STAR domain protein KH_1 PF00013.29 CDJ91426.1 - 5.2e-07 29.4 0.1 9.9e-07 28.5 0.1 1.4 1 0 0 1 1 1 1 KH domain Il13Ra_Ig PF18001.1 CDJ91426.1 - 0.097 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Interleukin-13 receptor subunit alpha Ig-like domain Vta1 PF04652.16 CDJ91427.1 - 0.00032 20.7 0.9 0.00038 20.4 0.9 1.1 1 0 0 1 1 1 1 Vta1 like Jnk-SapK_ap_N PF09744.9 CDJ91427.1 - 0.0041 17.4 3.2 0.0048 17.1 3.2 1.1 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 DUF4164 PF13747.6 CDJ91427.1 - 0.058 13.7 2.8 0.08 13.2 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) APG6_N PF17675.1 CDJ91427.1 - 0.062 13.8 4.8 0.076 13.5 4.8 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF1664 PF07889.12 CDJ91427.1 - 0.064 13.3 0.5 0.12 12.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Spc24 PF08286.11 CDJ91427.1 - 0.11 12.8 0.2 0.11 12.8 0.2 1.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Atg14 PF10186.9 CDJ91427.1 - 0.16 11.0 0.5 0.19 10.8 0.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SNAP PF14938.6 CDJ91428.1 - 4.7e-103 344.5 8.9 5.3e-103 344.3 8.9 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 CDJ91428.1 - 7.6e-06 26.1 9.0 0.022 15.0 1.6 3.4 2 1 0 3 3 3 2 Tetratricopeptide repeat NSF PF02071.20 CDJ91428.1 - 0.00025 21.2 21.5 2.5 9.2 0.8 8.2 8 1 1 9 9 8 1 Aromatic-di-Alanine (AdAR) repeat TPR_7 PF13176.6 CDJ91428.1 - 0.00037 20.3 4.4 8.1 6.7 0.1 5.3 4 1 2 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ91428.1 - 0.011 15.9 2.5 0.011 15.9 2.5 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF2076 PF09849.9 CDJ91428.1 - 0.038 14.0 0.1 0.065 13.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Glyco_hydro_9 PF00759.19 CDJ91428.1 - 0.098 12.1 2.8 0.11 11.9 2.8 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 RPN7 PF10602.9 CDJ91428.1 - 0.11 12.2 3.5 0.48 10.1 1.3 2.4 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_8 PF13181.6 CDJ91428.1 - 0.12 12.7 10.5 1.6 9.1 0.3 5.6 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ91428.1 - 0.15 11.9 17.6 18 5.4 0.4 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Spatacsin_C PF14649.6 CDJ91428.1 - 0.22 10.6 5.4 0.51 9.4 5.2 1.9 1 1 0 1 1 1 0 Spatacsin C-terminus TPR_2 PF07719.17 CDJ91428.1 - 0.77 10.0 25.7 0.38 11.0 0.3 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ91428.1 - 0.98 10.4 6.7 9.1 7.4 0.1 4.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ91428.1 - 4.1 8.0 10.0 1.5 9.4 0.9 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ91428.1 - 7.5 7.3 12.6 12 6.6 0.4 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat Myco_haema PF05692.12 CDJ91429.1 - 0.14 11.1 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Mycoplasma haemagglutinin Na_Ca_ex PF01699.24 CDJ91430.1 - 1.7e-52 177.4 49.6 5.6e-27 94.6 24.9 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein OATP PF03137.20 CDJ91432.1 - 1.9e-107 359.8 5.9 2.4e-107 359.5 5.9 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 CDJ91432.1 - 8.8e-13 47.9 18.9 9e-12 44.6 6.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.15 CDJ91432.1 - 0.0014 18.7 7.5 0.0014 18.7 7.5 2.0 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Cytochrome_B PF00033.19 CDJ91433.1 - 0.014 15.2 0.1 0.017 14.9 0.1 1.0 1 0 0 1 1 1 0 Cytochrome b/b6/petB SecG PF03840.14 CDJ91433.1 - 0.074 13.1 1.5 0.11 12.6 1.5 1.5 1 1 0 1 1 1 0 Preprotein translocase SecG subunit Cytochrom_B_N_2 PF13631.6 CDJ91433.1 - 0.12 12.3 0.7 0.14 12.2 0.7 1.0 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Chorion_3 PF05387.11 CDJ91433.1 - 0.53 9.9 4.8 0.56 9.8 4.8 1.0 1 0 0 1 1 1 0 Chorion family 3 I-set PF07679.16 CDJ91435.1 - 0 1086.3 2.8 6e-19 67.9 0.0 22.4 22 0 0 22 22 22 21 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ91435.1 - 2.4e-236 765.1 9.1 3.3e-13 50.0 0.0 21.5 21 0 0 21 21 21 21 Immunoglobulin domain Ig_2 PF13895.6 CDJ91435.1 - 1e-125 410.3 16.8 1.6e-08 34.7 0.0 21.5 21 1 0 21 21 21 18 Immunoglobulin domain ig PF00047.25 CDJ91435.1 - 1.2e-118 387.5 21.7 2.7e-11 43.5 0.0 21.2 21 0 0 21 21 21 20 Immunoglobulin domain Pkinase PF00069.25 CDJ91435.1 - 4e-72 242.7 0.0 6.5e-72 242.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain V-set PF07686.17 CDJ91435.1 - 7.4e-43 145.2 45.3 0.0015 18.6 0.1 27.1 21 11 0 21 21 21 11 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDJ91435.1 - 1.6e-39 133.8 8.0 0.0007 19.6 0.0 16.1 19 0 0 19 19 18 10 CD80-like C2-set immunoglobulin domain fn3 PF00041.21 CDJ91435.1 - 3.2e-38 130.0 5.5 9.2e-13 48.4 0.0 5.3 5 0 0 5 5 4 3 Fibronectin type III domain Pkinase_Tyr PF07714.17 CDJ91435.1 - 4.2e-36 124.6 0.1 1.2e-35 123.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Receptor_2B4 PF11465.8 CDJ91435.1 - 1.2e-25 89.8 2.2 1.3 9.3 0.0 14.1 14 0 0 14 14 13 5 Natural killer cell receptor 2B4 C1-set PF07654.15 CDJ91435.1 - 1.9e-17 63.4 7.1 1.1 9.7 0.0 13.1 15 0 0 15 15 14 4 Immunoglobulin C1-set domain Ig_6 PF18452.1 CDJ91435.1 - 8.5e-16 57.3 10.6 0.71 9.5 0.0 11.3 12 0 0 12 12 11 5 Immunoglobulin domain BiPBP_C PF06832.12 CDJ91435.1 - 3.8e-14 52.5 0.0 0.26 11.3 0.0 12.3 15 0 0 15 15 15 2 Penicillin-Binding Protein C-terminus Family Ig_5 PF16681.5 CDJ91435.1 - 3e-12 46.8 17.3 11 6.5 0.3 16.0 19 0 0 19 19 16 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 CDJ91435.1 - 1.9e-08 34.5 26.7 0.8 10.0 0.0 13.7 15 0 0 15 15 15 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 CDJ91435.1 - 1e-07 31.9 28.6 1.6 8.8 0.1 14.0 18 0 0 18 18 14 1 Izumo-like Immunoglobulin domain Kinase-like PF14531.6 CDJ91435.1 - 5.5e-06 25.9 0.0 9.7e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Tissue_fac PF01108.17 CDJ91435.1 - 1.4e-05 24.9 0.2 0.15 11.9 0.0 3.1 2 0 0 2 2 2 2 Tissue factor Kdo PF06293.14 CDJ91435.1 - 0.00071 19.0 0.9 0.0013 18.1 0.9 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDJ91435.1 - 0.0055 16.3 0.6 0.011 15.3 0.6 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CDJ91435.1 - 0.12 12.2 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family ELO PF01151.18 CDJ91436.1 - 8.1e-43 146.7 15.1 9.3e-43 146.5 15.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family RNase_Zc3h12a_2 PF14626.6 CDJ91436.1 - 0.085 13.1 0.6 0.17 12.1 0.1 1.7 1 1 1 2 2 2 0 Zc3h12a-like Ribonuclease NYN domain Rib_5-P_isom_A PF06026.14 CDJ91437.1 - 8.7e-59 198.0 0.0 1.2e-58 197.6 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 CDJ91437.1 - 0.072 13.0 0.1 1.7 8.5 0.0 2.1 2 0 0 2 2 2 0 DeoR C terminal sensor domain Sugar-bind PF04198.13 CDJ91437.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain Integrin_beta PF00362.18 CDJ91438.1 - 3.8e-104 347.7 0.0 5.3e-104 347.3 0.0 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.11 CDJ91438.1 - 2.8e-21 74.9 1.0 6e-21 73.9 1.0 1.6 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.12 CDJ91438.1 - 6.5e-18 65.0 2.7 6.5e-18 65.0 2.7 3.8 4 1 2 6 6 6 1 Integrin beta tail domain EGF_2 PF07974.13 CDJ91438.1 - 7.4e-07 29.4 87.8 8.1e-05 22.9 13.1 6.1 5 1 0 5 5 5 3 EGF-like domain CusF_Ec PF11604.8 CDJ91438.1 - 0.15 12.0 0.0 3.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Copper binding periplasmic protein CusF Collectrin PF16959.5 CDJ91438.1 - 0.31 10.8 1.7 0.68 9.7 1.7 1.5 1 0 0 1 1 1 0 Renal amino acid transporter I-EGF_1 PF18372.1 CDJ91438.1 - 0.51 10.5 82.2 0.079 13.1 7.2 5.6 6 0 0 6 6 6 0 Integrin beta epidermal growth factor like domain 1 Lipase_3 PF01764.25 CDJ91439.1 - 6.2e-35 120.1 0.0 8.6e-35 119.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CDJ91439.1 - 0.036 14.7 0.4 0.066 13.8 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2974 PF11187.8 CDJ91439.1 - 0.06 12.9 0.0 6.5 6.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) 7TM_GPCR_Srab PF10292.9 CDJ91440.1 - 2.2e-31 109.0 28.0 2.7e-31 108.7 28.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Srb PF02175.16 CDJ91440.1 - 1.5e-17 64.2 26.2 2.4e-17 63.5 26.2 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srb 7TM_GPCR_Sra PF02117.16 CDJ91440.1 - 1.1e-14 54.0 27.7 1.3e-14 53.8 27.7 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sra DUF202 PF02656.15 CDJ91440.1 - 4.3 7.8 6.2 4.1 7.9 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF202) UDPGT PF00201.18 CDJ91441.1 - 4.3e-63 213.8 0.3 5.6e-63 213.4 0.3 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ91441.1 - 8.4e-09 35.6 0.0 1.5e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_5 PF08323.11 CDJ91441.1 - 0.14 11.8 0.0 0.58 9.8 0.0 1.9 2 0 0 2 2 2 0 Starch synthase catalytic domain ShK PF01549.24 CDJ91442.1 - 9.7e-06 26.0 5.9 4.4e-05 23.9 5.9 2.1 1 1 0 1 1 1 1 ShK domain-like UDPGT PF00201.18 CDJ91443.1 - 3.4e-61 207.6 0.1 3.9e-61 207.4 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ91443.1 - 2.5e-09 37.4 0.0 5e-09 36.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 CDJ91444.1 - 1.7e-63 215.2 0.0 2e-63 214.9 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ91444.1 - 6.7e-09 35.9 0.0 1.1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_5 PF08323.11 CDJ91444.1 - 0.099 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain UDPGT PF00201.18 CDJ91445.1 - 8.7e-66 222.7 0.1 1e-65 222.5 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ91445.1 - 4.1e-10 39.9 0.0 6.4e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain FANCI_HD1 PF14679.6 CDJ91445.1 - 0.29 11.1 1.4 0.59 10.1 0.1 2.2 2 0 0 2 2 2 0 FANCI helical domain 1 UDPGT PF00201.18 CDJ91446.1 - 7.1e-61 206.5 0.1 8.8e-61 206.2 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ91446.1 - 1.1e-09 38.5 0.0 2.2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 CDJ91448.1 - 9.8e-63 212.6 0.0 1.1e-62 212.4 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ91448.1 - 5.1e-13 49.3 0.0 1.8e-12 47.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 CDJ91448.1 - 0.0061 15.8 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 1 MOSC_N PF03476.16 CDJ91449.1 - 2.3e-28 98.5 0.0 4.1e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 CDJ91449.1 - 1.3e-27 96.4 0.0 2.3e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 MOSC domain Phg_2220_C PF09524.10 CDJ91449.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Conserved phage C-terminus (Phg_2220_C) UDPGT PF00201.18 CDJ91450.1 - 1.7e-61 208.5 0.3 2e-61 208.3 0.3 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ91450.1 - 7.9e-11 42.2 0.0 1.4e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF4724 PF15852.5 CDJ91450.1 - 0.041 14.4 0.0 0.14 12.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4724) DUF4083 PF13314.6 CDJ91450.1 - 3 7.9 7.8 0.21 11.6 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) HAD PF12710.7 CDJ91451.1 - 5.5e-16 59.5 0.0 7.7e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDJ91451.1 - 3.2e-15 57.0 0.2 5.4e-15 56.2 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CDJ91451.1 - 0.00017 21.7 0.0 0.026 14.6 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 CDJ91451.1 - 0.0012 18.5 0.1 0.014 15.0 0.1 2.4 1 1 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Put_Phosphatase PF06888.12 CDJ91451.1 - 0.0039 16.6 0.0 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 Putative Phosphatase ShK PF01549.24 CDJ91452.1 - 0.00089 19.7 9.4 0.0054 17.2 9.4 2.3 1 1 0 1 1 1 1 ShK domain-like PIEZO PF15917.5 CDJ91453.1 - 0.028 13.9 15.4 0.029 13.9 15.4 1.2 1 0 0 1 1 1 0 Piezo Paf1 PF03985.13 CDJ91453.1 - 0.39 9.7 19.2 0.4 9.6 19.2 1.2 1 0 0 1 1 1 0 Paf1 DDHD PF02862.17 CDJ91453.1 - 0.68 10.0 7.1 0.73 9.9 7.1 1.2 1 0 0 1 1 1 0 DDHD domain G6B PF15096.6 CDJ91453.1 - 0.76 9.5 3.9 1.5 8.5 3.9 1.5 1 0 0 1 1 1 0 G6B family Asp-B-Hydro_N PF05279.11 CDJ91453.1 - 0.95 9.5 19.0 0.96 9.5 19.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DDRGK PF09756.9 CDJ91453.1 - 1 8.9 29.8 1.3 8.5 29.8 1.2 1 0 0 1 1 1 0 DDRGK domain Lin-8 PF03353.15 CDJ91453.1 - 1 8.8 17.2 1.3 8.5 17.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF775 PF05603.12 CDJ91453.1 - 1.2 8.6 6.9 1.5 8.3 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Ndc1_Nup PF09531.10 CDJ91453.1 - 1.6 7.4 7.7 1.5 7.4 7.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zip PF02535.22 CDJ91453.1 - 2.1 7.5 8.2 2 7.6 8.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter eIF3_subunit PF08597.10 CDJ91453.1 - 2.9 7.7 25.4 2.9 7.8 25.1 1.2 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit Presenilin PF01080.17 CDJ91453.1 - 3.5 6.3 14.3 3.3 6.4 14.3 1.1 1 0 0 1 1 1 0 Presenilin Roughex PF06020.11 CDJ91453.1 - 3.9 6.5 13.3 5.2 6.1 13.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF2151 PF10221.9 CDJ91453.1 - 4.3 5.8 12.9 4 5.9 12.9 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Peptidase_S64 PF08192.11 CDJ91453.1 - 4.5 5.6 11.4 4.4 5.7 11.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 TRAP_alpha PF03896.16 CDJ91453.1 - 4.6 6.4 10.4 5.7 6.1 10.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit EIIBC-GUT_N PF03612.14 CDJ91453.1 - 6.6 6.4 15.6 12 5.6 15.6 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RNA_pol_Rbc25 PF08292.12 CDJ91453.1 - 6.7 7.0 13.6 12 6.1 13.6 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 SLC12 PF03522.15 CDJ91453.1 - 7.1 5.5 13.7 7.1 5.5 13.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Borrelia_P83 PF05262.11 CDJ91453.1 - 7.4 4.9 17.8 6.6 5.1 17.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Sec62 PF03839.16 CDJ91453.1 - 7.6 6.0 15.2 9.9 5.6 15.2 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 GCD14 PF08704.10 CDJ91453.1 - 8.4 6.0 8.6 12 5.5 8.6 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Transposase_1 PF01359.18 CDJ91455.1 - 3.9e-09 36.2 0.7 3.9e-09 36.2 0.7 1.5 2 0 0 2 2 2 1 Transposase (partial DDE domain) DDE_3 PF13358.6 CDJ91455.1 - 7.2e-06 25.8 0.1 9.4e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_26 PF13443.6 CDJ91455.1 - 0.0011 19.3 0.0 0.0021 18.5 0.0 1.5 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_IclR PF09339.10 CDJ91455.1 - 0.0031 17.3 0.6 0.0057 16.4 0.0 1.7 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.7 CDJ91455.1 - 0.014 15.3 0.1 0.028 14.3 0.1 1.5 1 0 0 1 1 1 0 MarR family HTH_Tnp_ISL3 PF13542.6 CDJ91455.1 - 0.024 14.1 0.1 0.062 12.7 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.6 CDJ91455.1 - 0.03 13.9 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding CENP-B_N PF04218.13 CDJ91455.1 - 0.037 13.7 0.0 0.074 12.7 0.0 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain LacI PF00356.21 CDJ91455.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Sigma70_r3 PF04539.16 CDJ91455.1 - 0.096 12.8 0.1 11 6.2 0.0 2.8 1 1 1 3 3 3 0 Sigma-70 region 3 HTH_3 PF01381.22 CDJ91455.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix HTH_10 PF04967.12 CDJ91455.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain MFS_1_like PF12832.7 CDJ91456.1 - 0.033 13.1 2.0 0.037 12.9 2.0 1.0 1 0 0 1 1 1 0 MFS_1 like family RVT_1 PF00078.27 CDJ91457.1 - 6.3e-33 114.2 0.0 8.1e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Bestrophin PF01062.21 CDJ91458.1 - 1.4e-77 261.0 9.6 2e-77 260.5 9.6 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel B12D PF06522.11 CDJ91459.1 - 0.078 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Lectin_C PF00059.21 CDJ91460.1 - 5.1e-17 62.6 0.0 3e-07 31.1 0.1 2.3 2 1 0 2 2 2 2 Lectin C-type domain Intimin_C PF07979.11 CDJ91460.1 - 0.071 13.5 0.6 7.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Intimin C-type lectin domain RNA_pol_Rpb1_1 PF04997.12 CDJ91461.1 - 9e-111 370.1 0.3 1.8e-110 369.2 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 CDJ91461.1 - 3e-103 344.9 0.2 5.3e-103 344.1 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CDJ91461.1 - 4.5e-75 251.4 0.0 1.6e-74 249.6 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 CDJ91461.1 - 2.9e-66 223.0 1.6 5.8e-66 222.0 1.6 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 CDJ91461.1 - 6.3e-52 175.1 2.5 6.3e-52 175.1 2.5 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 CDJ91461.1 - 2e-45 154.6 0.0 6e-45 153.0 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CDJ91461.1 - 1.5e-38 131.0 0.1 4.1e-38 129.6 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Tyrosinase PF00264.20 CDJ91462.1 - 7.4e-15 55.8 0.0 7.7e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Laminin_G_2 PF02210.24 CDJ91463.1 - 8.2e-16 58.7 0.2 1.4e-06 28.9 0.0 3.4 3 0 0 3 3 3 2 Laminin G domain Laminin_G_1 PF00054.23 CDJ91463.1 - 6.4e-07 29.6 0.0 0.072 13.3 0.0 4.0 3 1 0 3 3 3 2 Laminin G domain DUF3188 PF11384.8 CDJ91463.1 - 0.007 16.0 0.2 0.15 11.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3188) PAG PF15347.6 CDJ91463.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched Zip PF02535.22 CDJ91464.1 - 2e-55 188.4 15.3 7.5e-55 186.5 15.3 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter DUF1129 PF06570.11 CDJ91464.1 - 0.038 13.5 6.9 0.75 9.2 1.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) DUF4271 PF14093.6 CDJ91464.1 - 2.2 8.1 10.4 1.9 8.4 0.5 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4271) Ank_4 PF13637.6 CDJ91465.1 - 1.9e-17 63.4 0.1 2.3e-06 28.0 0.4 4.8 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ91465.1 - 4.1e-17 62.5 0.2 6.6e-05 23.4 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ91465.1 - 8.8e-12 44.9 2.0 0.006 17.0 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 CDJ91465.1 - 1.1e-09 37.7 0.9 0.0028 18.0 0.0 5.9 5 1 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 CDJ91465.1 - 4.6e-07 30.0 1.4 0.021 15.2 0.3 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Complex1_LYR PF05347.15 CDJ91466.1 - 2.5e-11 43.4 0.2 2.5e-11 43.4 0.2 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) DNA_alkylation PF08713.11 CDJ91466.1 - 0.032 14.0 1.5 0.51 10.0 0.1 2.2 2 0 0 2 2 2 0 DNA alkylation repair enzyme Kelch_1 PF01344.25 CDJ91467.1 - 2.5e-83 273.4 17.3 1.2e-16 60.0 0.3 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CDJ91467.1 - 3.3e-40 135.1 1.3 9.7e-07 28.9 0.0 6.3 3 1 3 6 6 6 5 Kelch motif BACK PF07707.15 CDJ91467.1 - 5.9e-35 119.5 1.0 1.4e-34 118.3 0.3 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 CDJ91467.1 - 3e-31 107.9 1.8 5.1e-31 107.2 1.3 1.7 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 CDJ91467.1 - 6.8e-26 89.2 5.5 8.4e-06 25.6 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 CDJ91467.1 - 2.5e-25 88.2 2.2 6.1e-05 23.0 0.1 5.4 3 1 2 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ91467.1 - 1.7e-16 60.0 9.0 0.011 16.0 0.1 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ91467.1 - 2.6e-07 30.5 0.8 3 7.9 0.0 5.3 5 0 0 5 5 5 3 Kelch motif PQQ_3 PF13570.6 CDJ91467.1 - 0.0097 16.4 14.9 2.5 8.7 0.4 5.2 5 0 0 5 5 5 2 PQQ-like domain DUF3342 PF11822.8 CDJ91467.1 - 0.054 13.7 0.6 0.51 10.6 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) DUF4851 PF16143.5 CDJ91467.1 - 0.12 11.8 0.0 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4851) UPF0220 PF05255.11 CDJ91468.1 - 4.2e-42 143.5 6.4 4.8e-42 143.3 6.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF2721 PF11026.8 CDJ91468.1 - 1.9 8.4 8.2 5.1 7.0 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) ABC_tran PF00005.27 CDJ91469.1 - 3e-32 112.0 0.0 5.2e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 CDJ91469.1 - 3.2e-32 112.3 7.6 4.1e-32 111.9 7.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 CDJ91469.1 - 1.5e-05 24.5 1.3 0.0014 18.1 0.0 2.2 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 CDJ91469.1 - 0.00017 21.8 0.1 0.00066 19.8 0.1 1.9 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_29 PF13555.6 CDJ91469.1 - 0.0014 18.3 0.1 0.0035 17.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 CDJ91469.1 - 0.015 15.7 0.0 0.043 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.13 CDJ91469.1 - 0.031 13.4 0.0 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 CDJ91469.1 - 0.042 13.6 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CDJ91469.1 - 0.051 13.9 0.1 0.21 11.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CDJ91469.1 - 0.054 13.7 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 CDJ91469.1 - 0.065 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 CDJ91469.1 - 0.083 11.7 0.3 6.2 5.5 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class G-alpha PF00503.20 CDJ91469.1 - 0.095 11.8 0.0 0.25 10.5 0.0 1.7 2 0 0 2 2 2 0 G-protein alpha subunit RsgA_GTPase PF03193.16 CDJ91469.1 - 0.1 12.5 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 CDJ91469.1 - 0.12 12.4 0.0 0.33 11.1 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase E1-E2_ATPase PF00122.20 CDJ91470.1 - 0.0025 17.4 0.5 0.0025 17.4 0.5 2.9 2 1 0 2 2 2 1 E1-E2 ATPase DUF3278 PF11683.8 CDJ91470.1 - 0.011 15.9 0.8 0.067 13.3 0.6 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) Erg28 PF03694.13 CDJ91470.1 - 0.014 15.8 0.2 0.05 14.0 0.2 1.9 1 0 0 1 1 1 0 Erg28 like protein PI-PLC-X PF00388.19 CDJ91470.1 - 0.096 12.3 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain EVC2_like PF12297.8 CDJ91470.1 - 1.1 7.9 3.4 1.6 7.4 0.6 2.3 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein Ig_3 PF13927.6 CDJ91471.1 - 2.6e-21 76.0 5.2 1.8e-05 25.2 0.1 5.2 7 0 0 7 7 7 3 Immunoglobulin domain ig PF00047.25 CDJ91471.1 - 1.9e-18 66.4 1.1 2.2e-05 24.5 0.0 4.5 4 0 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 CDJ91471.1 - 7.6e-16 58.0 1.8 0.0012 18.9 0.0 4.9 4 1 0 4 4 4 3 Immunoglobulin I-set domain V-set PF07686.17 CDJ91471.1 - 8.7e-13 48.4 5.8 0.067 13.4 0.3 6.4 3 3 1 5 5 5 4 Immunoglobulin V-set domain Ig_2 PF13895.6 CDJ91471.1 - 1.5e-09 38.0 5.4 0.00012 22.4 0.3 5.0 6 0 0 6 6 6 2 Immunoglobulin domain fn3 PF00041.21 CDJ91471.1 - 8.9e-05 22.8 0.0 0.11 12.9 0.0 2.8 2 0 0 2 2 2 2 Fibronectin type III domain Ig_6 PF18452.1 CDJ91471.1 - 0.0013 18.3 0.1 0.66 9.6 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin domain Ig_4 PF16680.5 CDJ91471.1 - 0.0019 18.4 1.1 0.086 13.1 0.0 4.0 4 1 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Pur_ac_phosph_N PF16656.5 CDJ91471.1 - 0.054 14.1 0.1 1.1 9.8 0.0 2.7 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Noc2 PF03715.13 CDJ91474.1 - 0.0027 17.0 1.0 0.0084 15.4 0.0 2.1 2 0 0 2 2 2 1 Noc2p family FAM76 PF16046.5 CDJ91474.1 - 1.2 8.4 10.4 2 7.7 10.4 1.3 1 0 0 1 1 1 0 FAM76 protein GCFC PF07842.12 CDJ91475.1 - 1.1e-71 241.7 14.4 1.6e-71 241.2 14.4 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 CDJ91475.1 - 9.5e-11 41.4 1.1 1.7e-10 40.6 1.1 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CDJ91475.1 - 0.054 13.6 0.4 0.11 12.6 0.4 1.6 1 0 0 1 1 1 0 G-patch domain HTH_48 PF17906.1 CDJ91475.1 - 0.51 10.5 1.7 1.8 8.8 0.1 2.6 3 0 0 3 3 3 0 HTH domain in Mos1 transposase DUF1759 PF03564.15 CDJ91476.1 - 5.3e-21 75.1 0.1 1.2e-20 74.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 CDJ91476.1 - 4.7e-08 33.0 0.1 4.7e-08 33.0 0.1 2.0 2 1 0 2 2 2 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 CDJ91476.1 - 0.00029 21.4 0.3 0.0012 19.4 0.2 2.0 1 1 1 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 CDJ91476.1 - 0.00083 19.1 0.2 0.002 17.9 0.2 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.8 CDJ91476.1 - 0.00091 18.8 0.4 0.0017 17.9 0.4 1.4 1 0 0 1 1 1 1 Ty3 transposon peptidase gag-asp_proteas PF13975.6 CDJ91476.1 - 0.0022 18.5 0.1 0.006 17.1 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF5641 PF18701.1 CDJ91477.1 - 9.2e-16 57.8 0.3 1.3e-15 57.3 0.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5641) 7tm_1 PF00001.21 CDJ91479.1 - 1.5e-36 126.1 10.1 1.5e-36 126.1 10.1 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CDJ91479.1 - 1.2e-09 38.1 12.8 1.7e-09 37.7 12.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 CDJ91479.1 - 4.4e-07 29.5 12.5 4.4e-07 29.5 12.5 1.7 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF1772 PF08592.11 CDJ91479.1 - 0.003 17.9 0.6 0.007 16.7 0.2 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) DUF2116 PF09889.9 CDJ91479.1 - 0.017 15.1 3.0 0.45 10.5 0.0 3.3 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) UDPG_MGDP_dh_N PF03721.14 CDJ91480.1 - 3.9e-64 215.7 0.0 6e-64 215.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 CDJ91480.1 - 1.5e-37 128.2 0.3 6.3e-35 119.8 0.1 3.0 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 CDJ91480.1 - 2.2e-31 107.9 0.0 4.3e-31 107.0 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain 3HCDH_N PF02737.18 CDJ91480.1 - 0.0055 16.6 0.0 0.54 10.1 0.0 2.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 CDJ91480.1 - 0.016 15.4 0.0 0.86 9.8 0.0 3.1 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Activin_recp PF01064.23 CDJ91483.1 - 0.31 12.1 16.7 0.59 11.3 16.7 1.5 1 1 0 1 1 1 0 Activin types I and II receptor domain Activin_recp PF01064.23 CDJ91484.1 - 0.001 20.1 14.3 0.0017 19.4 14.2 1.5 1 1 1 2 2 2 2 Activin types I and II receptor domain Toxin_TOLIP PF00087.21 CDJ91484.1 - 2.8 8.2 16.9 7.6 6.9 16.9 1.8 1 1 0 1 1 1 0 Snake toxin and toxin-like protein IF4E PF01652.18 CDJ91485.1 - 2.9e-48 163.7 0.1 5.9e-48 162.7 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Patched PF02460.18 CDJ91486.1 - 2.5e-268 892.5 3.5 2.9e-268 892.3 3.5 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 CDJ91486.1 - 9.2e-45 152.2 7.7 9.2e-45 152.2 7.7 3.3 3 1 1 4 4 4 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 CDJ91486.1 - 0.00013 21.0 10.9 0.00013 21.0 10.9 2.3 2 0 0 2 2 2 1 MMPL family Gsf2 PF11055.8 CDJ91486.1 - 0.19 10.5 0.5 0.35 9.6 0.5 1.3 1 0 0 1 1 1 0 Glucose signalling factor 2 LRR_8 PF13855.6 CDJ91487.1 - 6.9e-27 93.0 5.1 6.4e-11 41.8 2.6 4.2 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 CDJ91487.1 - 1.3e-14 54.1 9.7 3.7e-05 24.0 0.9 5.8 3 2 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDJ91487.1 - 3.5e-09 35.9 8.5 1.7 9.5 1.2 7.5 6 1 2 8 8 8 4 Leucine Rich Repeat LRR_6 PF13516.6 CDJ91487.1 - 1.2e-06 28.1 13.2 1.3 9.3 0.1 7.5 8 0 0 8 8 8 2 Leucine Rich repeat LRR_9 PF14580.6 CDJ91487.1 - 1.6e-05 24.5 0.0 0.41 10.1 0.0 3.0 1 1 1 3 3 3 2 Leucine-rich repeat DUF1068 PF06364.12 CDJ91487.1 - 0.062 13.2 0.8 1.7 8.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1068) DHHC PF01529.20 CDJ91488.1 - 3.9e-29 101.4 9.2 5.3e-29 101.0 9.2 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF5074 PF16819.5 CDJ91488.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5074) C1_1 PF00130.22 CDJ91488.1 - 1.3 9.0 13.5 2.2 8.2 13.5 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) EGF_CA PF07645.15 CDJ91489.1 - 0.0035 17.5 6.2 0.0035 17.5 6.2 2.8 3 1 1 4 4 4 1 Calcium-binding EGF domain EGF_3 PF12947.7 CDJ91489.1 - 0.026 14.7 0.6 0.026 14.7 0.6 2.9 2 2 0 2 2 2 0 EGF domain UPF0242 PF06785.11 CDJ91490.1 - 0.32 11.1 2.4 0.58 10.2 2.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ABC_tran PF00005.27 CDJ91491.1 - 5.3e-29 101.5 0.0 7.2e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CDJ91491.1 - 9.3e-07 28.5 1.0 0.00059 19.3 0.1 2.3 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 CDJ91491.1 - 0.01 15.5 0.6 0.03 14.0 0.6 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CDJ91491.1 - 0.016 15.6 0.6 0.045 14.1 0.6 1.7 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 CDJ91491.1 - 0.038 14.1 0.1 0.1 12.7 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 CDJ91491.1 - 0.047 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 CDJ91491.1 - 0.057 13.2 0.0 1.6 8.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 CDJ91491.1 - 0.077 12.7 0.3 5.1 6.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 CDJ91491.1 - 0.079 12.7 0.3 0.14 11.9 0.0 1.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.6 CDJ91491.1 - 0.37 11.1 1.6 3.3 8.0 1.2 2.3 1 1 0 1 1 1 0 AAA domain gag-asp_proteas PF13975.6 CDJ91492.1 - 0.00031 21.2 0.0 0.0011 19.4 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Trehalase PF01204.18 CDJ91493.1 - 5.1e-74 249.9 0.0 6.3e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 CDJ91493.1 - 0.0034 16.4 0.0 0.0051 15.8 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase SPT2 PF08243.11 CDJ91494.1 - 1e-10 42.1 11.6 1e-10 42.1 11.6 5.4 3 2 2 5 5 5 1 SPT2 chromatin protein WSK PF03832.13 CDJ91494.1 - 0.0028 17.3 1.3 0.013 15.2 1.3 2.2 1 0 0 1 1 1 1 WSK motif Cadherin_pro PF08758.11 CDJ91495.1 - 0.00013 22.0 0.0 0.00043 20.4 0.0 1.8 1 0 0 1 1 1 1 Cadherin prodomain like fn3 PF00041.21 CDJ91495.1 - 0.00025 21.3 0.0 0.00063 20.0 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain Cadherin PF00028.17 CDJ91495.1 - 0.0049 17.3 0.0 0.031 14.7 0.0 2.1 2 0 0 2 2 2 1 Cadherin domain Y_Y_Y PF07495.13 CDJ91495.1 - 0.18 11.8 0.2 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Y_Y_Y domain C2 PF00168.30 CDJ91496.1 - 3.2e-10 40.2 0.0 1.4e-09 38.1 0.0 2.2 2 0 0 2 2 2 1 C2 domain C1_1 PF00130.22 CDJ91496.1 - 6.4e-09 35.6 11.3 1.1e-08 34.8 11.3 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 CDJ91496.1 - 0.0015 18.8 6.2 0.0015 18.8 6.2 2.2 2 0 0 2 2 2 1 C1 domain DUF2142 PF09913.9 CDJ91496.1 - 0.015 14.2 1.5 0.023 13.6 1.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) zf-RING_9 PF13901.6 CDJ91496.1 - 0.044 13.8 9.0 0.1 12.6 9.0 1.5 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Zf_RING PF16744.5 CDJ91496.1 - 0.05 13.7 7.4 0.067 13.3 5.8 2.1 2 0 0 2 2 2 0 KIAA1045 RING finger Slp PF03843.13 CDJ91496.1 - 0.069 12.5 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family Prok-RING_1 PF14446.6 CDJ91496.1 - 0.24 11.4 7.7 0.48 10.4 7.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.29 CDJ91496.1 - 1.8 8.5 10.9 4.3 7.3 10.9 1.7 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 CDJ91496.1 - 1.9 8.1 8.2 5.9 6.6 8.2 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Mucin PF01456.17 CDJ91496.1 - 5.8 6.9 17.7 0.34 10.9 11.6 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein RGS-like PF09128.11 CDJ91497.1 - 7.3e-56 188.9 0.1 4.5e-55 186.3 0.0 2.4 2 0 0 2 2 2 1 Regulator of G protein signalling-like domain PH_16 PF17838.1 CDJ91497.1 - 7.2e-39 132.5 0.0 1.6e-38 131.3 0.0 1.6 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.20 CDJ91497.1 - 9.8e-34 117.2 1.6 3e-33 115.6 1.6 1.9 1 0 0 1 1 1 1 RhoGEF domain PDZ PF00595.24 CDJ91497.1 - 1.3e-12 47.9 0.0 2.9e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDJ91497.1 - 3.4e-11 42.8 0.0 8.7e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ91497.1 - 8.2e-06 26.1 0.0 2.5e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 PDZ domain C1_1 PF00130.22 CDJ91497.1 - 1.9e-05 24.5 8.0 4.1e-05 23.4 8.0 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RGS PF00615.19 CDJ91497.1 - 0.003 17.8 0.1 0.017 15.4 0.0 2.4 2 0 0 2 2 2 1 Regulator of G protein signaling domain PH PF00169.29 CDJ91497.1 - 0.051 14.1 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 PH domain Tricorn_PDZ PF14685.6 CDJ91497.1 - 0.055 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain C1_2 PF03107.16 CDJ91497.1 - 0.087 13.2 4.9 0.2 12.0 4.9 1.6 1 0 0 1 1 1 0 C1 domain SpecificRecomb PF10136.9 CDJ91497.1 - 0.14 10.5 1.2 0.26 9.6 1.2 1.4 1 0 0 1 1 1 0 Site-specific recombinase SUa-2TM PF18179.1 CDJ91498.1 - 0.071 12.4 0.1 0.093 12.0 0.1 1.1 1 0 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain OATP PF03137.20 CDJ91499.1 - 0.00067 18.1 0.5 0.00084 17.8 0.5 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family CAP PF00188.26 CDJ91501.1 - 1.4e-12 48.6 0.6 1.4e-12 48.6 0.6 2.7 2 1 0 2 2 2 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ91501.1 - 0.052 13.8 0.1 0.052 13.8 0.1 2.5 2 2 0 2 2 2 0 Ancylostoma-associated secreted protein related Mitofilin PF09731.9 CDJ91501.1 - 3.6 6.3 14.6 4.3 6.0 14.6 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CAP PF00188.26 CDJ91502.1 - 4.4e-14 53.4 0.2 4.4e-14 53.4 0.2 2.2 2 1 0 2 2 2 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ91502.1 - 0.018 15.3 0.0 0.045 14.0 0.0 1.8 1 1 0 1 1 1 0 Ancylostoma-associated secreted protein related bZIP_2 PF07716.15 CDJ91504.1 - 1e-08 35.1 15.2 1.7e-08 34.4 15.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper EURL PF06937.11 CDJ91504.1 - 0.1 12.0 1.3 0.11 11.9 1.3 1.2 1 0 0 1 1 1 0 EURL protein BAR_2 PF10455.9 CDJ91505.1 - 0.0033 16.6 0.1 0.0035 16.5 0.1 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking REV1_C PF16727.5 CDJ91505.1 - 0.016 15.6 0.1 0.25 11.7 0.1 2.0 1 1 0 1 1 1 0 DNA repair protein REV1 C-terminal domain phiKZ_IP PF12699.7 CDJ91505.1 - 0.032 13.4 0.2 0.04 13.1 0.2 1.2 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins DUF234 PF03008.14 CDJ91505.1 - 0.094 13.2 0.1 0.13 12.7 0.1 1.3 1 0 0 1 1 1 0 Archaea bacterial proteins of unknown function DUF3091 PF11291.8 CDJ91505.1 - 0.12 12.6 1.0 0.2 11.8 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3091) HlyIII PF03006.20 CDJ91506.1 - 1.3e-68 231.0 21.5 1.7e-68 230.7 21.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related AAA PF00004.29 CDJ91507.1 - 1.4e-38 132.3 0.0 3.5e-38 131.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDJ91507.1 - 1e-06 28.8 0.1 8.1e-06 25.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 CDJ91507.1 - 3.8e-06 26.6 0.2 3.8e-06 26.6 0.2 2.4 2 1 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 CDJ91507.1 - 1.1e-05 25.9 2.4 0.00068 20.1 0.1 2.8 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CDJ91507.1 - 1.5e-05 25.3 0.2 0.0021 18.4 0.0 2.7 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 CDJ91507.1 - 2.8e-05 23.9 0.0 4.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CDJ91507.1 - 6.5e-05 23.1 0.2 0.002 18.3 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.6 CDJ91507.1 - 0.00011 22.3 0.0 0.00025 21.1 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.14 CDJ91507.1 - 0.00023 21.3 0.0 0.0005 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TniB PF05621.11 CDJ91507.1 - 0.00027 20.4 0.2 0.14 11.5 0.0 3.0 2 1 1 3 3 3 1 Bacterial TniB protein AAA_18 PF13238.6 CDJ91507.1 - 0.00056 20.5 0.0 0.0013 19.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CDJ91507.1 - 0.0012 19.3 0.0 0.0027 18.1 0.0 1.8 1 1 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 CDJ91507.1 - 0.0014 18.4 0.0 0.004 16.9 0.0 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 CDJ91507.1 - 0.0019 18.1 0.0 0.0044 16.9 0.0 1.6 2 0 0 2 2 1 1 Bacterial dnaA protein NACHT PF05729.12 CDJ91507.1 - 0.0037 17.2 0.2 0.068 13.1 0.0 2.4 1 1 1 2 2 2 1 NACHT domain AAA_25 PF13481.6 CDJ91507.1 - 0.004 16.8 0.8 0.21 11.2 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 CDJ91507.1 - 0.0055 16.4 0.0 0.015 15.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CDJ91507.1 - 0.0056 16.1 0.8 0.013 14.9 0.1 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 CDJ91507.1 - 0.0057 15.9 0.0 0.0093 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 CDJ91507.1 - 0.0081 16.7 0.0 0.32 11.5 0.0 2.6 2 1 0 2 2 2 1 ABC transporter Rad17 PF03215.15 CDJ91507.1 - 0.018 15.0 0.0 0.049 13.5 0.0 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain TsaE PF02367.17 CDJ91507.1 - 0.027 14.5 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 CDJ91507.1 - 0.028 14.5 0.0 0.067 13.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.6 CDJ91507.1 - 0.03 14.6 0.0 0.08 13.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 CDJ91507.1 - 0.03 14.2 0.0 0.051 13.4 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 CDJ91507.1 - 0.034 13.3 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain SKI PF01202.22 CDJ91507.1 - 0.049 13.8 0.1 0.23 11.6 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase AAA_21 PF13304.6 CDJ91507.1 - 0.054 13.3 0.1 9.9 5.9 0.0 2.4 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ATPase PF06745.13 CDJ91507.1 - 0.065 12.6 0.1 1.5 8.1 0.0 2.3 1 1 0 2 2 2 0 KaiC ATPase_2 PF01637.18 CDJ91507.1 - 0.07 13.0 0.1 0.36 10.7 0.0 2.0 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Glyco_hydro_3_C PF01915.22 CDJ91507.1 - 0.11 12.5 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain AAA_17 PF13207.6 CDJ91507.1 - 0.11 12.9 0.0 0.36 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain tRNA_lig_kinase PF08303.11 CDJ91507.1 - 0.15 12.2 0.0 0.62 10.1 0.0 1.9 2 0 0 2 2 2 0 tRNA ligase kinase domain Parvo_NS1 PF01057.17 CDJ91507.1 - 0.16 11.0 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Pkinase_Tyr PF07714.17 CDJ91508.1 - 8.8e-57 192.3 0.0 1.3e-56 191.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ91508.1 - 1.6e-38 132.6 0.0 2.7e-37 128.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 CDJ91508.1 - 0.00043 20.3 0.0 0.0032 17.4 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ91508.1 - 0.009 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDJ91508.1 - 0.0097 14.9 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain TIL PF01826.17 CDJ91508.1 - 2.2 8.6 6.2 29 5.0 0.1 2.4 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain LRR_8 PF13855.6 CDJ91509.1 - 6.4e-16 57.9 11.9 4.2e-08 32.8 0.3 4.7 1 1 5 6 6 6 6 Leucine rich repeat 7tm_1 PF00001.21 CDJ91509.1 - 2.6e-11 43.4 3.7 4.8e-11 42.5 3.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_5 PF13306.6 CDJ91509.1 - 4.7e-09 36.3 0.2 0.0031 17.5 0.1 2.5 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 CDJ91509.1 - 4.8e-08 33.2 12.8 0.00061 20.1 1.2 6.1 3 3 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDJ91509.1 - 0.027 14.0 2.1 0.093 12.2 0.3 2.4 1 1 2 3 3 3 0 Leucine-rich repeat LRR_1 PF00560.33 CDJ91509.1 - 0.68 10.7 4.0 64 4.7 0.2 5.0 5 1 0 5 5 5 0 Leucine Rich Repeat Lipase_3 PF01764.25 CDJ91510.1 - 9.6e-29 100.1 0.0 1.4e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.13 CDJ91510.1 - 0.029 14.2 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ephrin_rec_like PF07699.13 CDJ91512.1 - 3.8e-38 129.0 36.7 1.4e-13 50.3 3.4 4.8 4 0 0 4 4 4 4 Putative ephrin-receptor like EGF_3 PF12947.7 CDJ91512.1 - 5.2e-06 26.5 6.5 5.2e-06 26.5 6.5 3.2 2 0 0 2 2 2 1 EGF domain EGF PF00008.27 CDJ91512.1 - 0.0003 21.0 22.9 0.0019 18.5 8.4 5.3 7 0 0 7 7 7 2 EGF-like domain cEGF PF12662.7 CDJ91512.1 - 0.00088 19.2 3.4 0.00088 19.2 3.4 7.3 8 1 0 8 8 8 2 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 CDJ91512.1 - 0.029 14.4 0.4 0.029 14.4 0.4 4.9 5 0 0 5 5 5 0 MSP1 EGF domain 1 DDE_Tnp_1_7 PF13843.6 CDJ91513.1 - 4.3e-86 289.4 0.0 5e-86 289.2 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.21 CDJ91513.1 - 0.00053 19.7 0.0 0.00085 19.0 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain C2 PF00168.30 CDJ91514.1 - 1.2e-05 25.6 0.0 1.5e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 C2 domain Lipase_3 PF01764.25 CDJ91516.1 - 1e-36 125.9 0.0 1.9e-36 125.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 CDJ91516.1 - 0.022 14.3 0.3 0.25 10.8 0.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 CDJ91516.1 - 0.095 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FBD PF08387.10 CDJ91516.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 FBD Abhydrolase_5 PF12695.7 CDJ91516.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 CDJ91516.1 - 0.19 11.8 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Mito_carr PF00153.27 CDJ91517.1 - 2.3e-26 91.5 0.1 1.3e-19 69.8 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein tRNA-synt_1e PF01406.19 CDJ91519.1 - 1.3e-123 412.1 2.2 4.7e-123 410.4 2.2 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 CDJ91519.1 - 1.1e-07 31.0 2.1 0.00052 18.9 0.1 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1c PF00749.21 CDJ91519.1 - 0.00058 18.8 3.0 0.00064 18.7 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.18 CDJ91519.1 - 0.0033 16.4 3.5 0.031 13.2 0.0 3.2 3 1 1 4 4 4 1 tRNA synthetases class I (K) tRNA-synt_1 PF00133.22 CDJ91519.1 - 0.0067 14.7 0.1 0.13 10.5 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) NDUFB10 PF10249.9 CDJ91519.1 - 0.028 14.9 0.3 0.11 13.0 0.3 2.0 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 Terminase_4 PF05119.12 CDJ91519.1 - 2.8 8.4 6.0 7.8 7.0 0.0 3.9 4 1 0 4 4 4 0 Phage terminase, small subunit IPP-2 PF04979.14 CDJ91521.1 - 1.9e-34 119.2 1.5 2.5e-34 118.9 1.5 1.1 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) Nucleoside_tran PF01733.18 CDJ91522.1 - 1.5e-65 221.6 27.6 4.6e-64 216.7 23.4 2.9 1 1 2 3 3 3 1 Nucleoside transporter I-set PF07679.16 CDJ91523.1 - 2.1e-109 357.8 19.5 1.1e-15 57.4 0.0 15.0 14 0 0 14 14 14 12 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ91523.1 - 1.5e-88 291.4 10.2 6.9e-16 58.6 0.1 14.2 14 0 0 14 14 13 11 Immunoglobulin domain fn3 PF00041.21 CDJ91523.1 - 4.3e-80 264.1 10.7 3.1e-14 53.1 0.0 8.3 9 0 0 9 9 9 6 Fibronectin type III domain Ig_2 PF13895.6 CDJ91523.1 - 4.1e-40 136.0 8.9 9.3e-12 45.1 0.2 11.6 12 0 0 12 12 12 6 Immunoglobulin domain ig PF00047.25 CDJ91523.1 - 3.8e-38 129.5 17.9 3.2e-08 33.6 0.0 12.0 12 0 0 12 12 11 8 Immunoglobulin domain V-set PF07686.17 CDJ91523.1 - 3.2e-15 56.2 19.6 0.022 14.9 0.2 13.5 11 5 0 11 11 10 3 Immunoglobulin V-set domain Izumo-Ig PF16706.5 CDJ91523.1 - 1e-12 47.9 0.9 0.2 11.7 0.1 7.5 8 0 0 8 8 8 2 Izumo-like Immunoglobulin domain Tissue_fac PF01108.17 CDJ91523.1 - 5.3e-07 29.5 2.7 0.33 10.8 0.6 4.5 4 0 0 4 4 4 3 Tissue factor Pur_ac_phosph_N PF16656.5 CDJ91523.1 - 9.7e-07 29.3 3.4 2.9 8.5 0.1 6.6 5 0 0 5 5 5 2 Purple acid Phosphatase, N-terminal domain Ig_6 PF18452.1 CDJ91523.1 - 3.2e-06 26.6 0.0 0.57 9.8 0.0 4.6 4 0 0 4 4 4 2 Immunoglobulin domain C2-set_2 PF08205.12 CDJ91523.1 - 7.4e-06 25.9 1.0 1.1 9.4 0.0 7.0 8 0 0 8 8 8 1 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 CDJ91523.1 - 0.00013 22.1 12.5 0.22 11.8 0.3 8.9 8 0 0 8 8 8 1 T-cell surface glycoprotein CD3 delta chain BiPBP_C PF06832.12 CDJ91523.1 - 0.026 14.6 0.0 4.7 7.3 0.0 4.4 5 0 0 5 5 4 0 Penicillin-Binding Protein C-terminus Family Receptor_2B4 PF11465.8 CDJ91523.1 - 0.12 12.6 12.7 5 7.4 0.0 7.2 8 1 1 9 9 8 0 Natural killer cell receptor 2B4 Adeno_E3_CR1 PF02440.15 CDJ91523.1 - 0.12 12.1 10.2 1.6 8.5 0.1 5.1 6 0 0 6 6 6 0 Adenovirus E3 region protein CR1 FERM_C PF09380.10 CDJ91525.1 - 9.1e-21 74.1 0.0 1.9e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 CDJ91525.1 - 8.3e-20 70.5 0.2 7.7e-18 64.2 0.1 2.5 2 0 0 2 2 2 1 FERM N-terminal domain FERM_M PF00373.18 CDJ91525.1 - 1.2e-19 70.8 0.0 2e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 FERM central domain FA PF08736.11 CDJ91525.1 - 3.7e-16 58.9 3.0 7.3e-16 58.0 3.0 1.5 1 0 0 1 1 1 1 FERM adjacent (FA) SCVP PF17619.2 CDJ91526.1 - 4.4e-99 325.6 21.9 3.9e-25 88.5 0.1 6.1 5 1 1 6 6 6 6 Secreted clade V proteins DsrD PF08679.11 CDJ91526.1 - 0.0081 16.4 3.3 9 6.6 0.1 4.1 4 0 0 4 4 4 1 Dissimilatory sulfite reductase D (DsrD) RII_binding_1 PF10522.9 CDJ91526.1 - 0.011 15.8 4.8 74 4.0 0.0 6.1 8 0 0 8 8 8 0 RII binding domain DUF3439 PF11921.8 CDJ91526.1 - 0.012 15.5 32.3 0.25 11.3 3.0 5.3 5 0 0 5 5 5 0 Domain of unknown function (DUF3439) RFX5_N PF18326.1 CDJ91526.1 - 0.014 15.1 0.7 3.6 7.4 0.1 3.5 3 0 0 3 3 3 0 RFX5 N-terminal domain DUF866 PF05907.13 CDJ91526.1 - 0.028 14.3 1.0 21 5.0 0.1 3.2 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF866) DUF4227 PF14004.6 CDJ91526.1 - 0.094 12.7 0.1 22 5.1 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) DUF3600 PF12207.8 CDJ91526.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) Fes1 PF08609.10 CDJ91526.1 - 0.14 13.0 0.1 82 4.2 0.1 4.0 5 0 0 5 5 5 0 Nucleotide exchange factor Fes1 DUF3094 PF11293.8 CDJ91526.1 - 0.25 11.1 3.0 9.4 6.0 0.4 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) SCVP PF17619.2 CDJ91527.1 - 1.7e-112 368.6 9.7 2.2e-23 82.9 0.0 5.1 5 0 0 5 5 5 5 Secreted clade V proteins Anophelin PF10731.9 CDJ91527.1 - 0.0046 16.8 0.7 9 6.2 0.0 3.6 4 0 0 4 4 4 2 Thrombin inhibitor from mosquito DnaT PF17948.1 CDJ91527.1 - 0.022 14.4 0.7 8.8 6.1 0.0 3.0 3 0 0 3 3 3 0 DnaT DNA-binding domain DUF4227 PF14004.6 CDJ91527.1 - 0.025 14.6 0.2 5.6 7.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4227) DUF1242 PF06842.12 CDJ91527.1 - 0.028 14.2 0.1 2 8.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1242) DUF866 PF05907.13 CDJ91527.1 - 0.077 12.9 0.2 38 4.2 0.0 3.5 5 0 0 5 5 5 0 Eukaryotic protein of unknown function (DUF866) KCNQ2_u3 PF16642.5 CDJ91527.1 - 0.43 11.6 5.6 3.8 8.5 0.7 3.4 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 DUF3439 PF11921.8 CDJ91527.1 - 0.58 10.1 13.0 0.21 11.6 4.6 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3439) VraX PF17412.2 CDJ91528.1 - 0.048 13.3 0.1 0.14 11.9 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function DUF1298 PF06974.13 CDJ91528.1 - 0.076 13.0 0.0 0.53 10.2 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1298) ASC PF00858.24 CDJ91529.1 - 9.7e-54 183.0 1.5 1.3e-53 182.6 1.5 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.24 CDJ91530.1 - 1.4e-24 86.9 11.9 1.5e-24 86.8 11.9 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF5583 PF17821.1 CDJ91530.1 - 0.061 13.3 0.4 0.17 11.8 0.4 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5583) DUF2973 PF11189.8 CDJ91531.1 - 1.6 8.9 3.8 2.2 8.4 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) MCM PF00493.23 CDJ91532.1 - 1.8e-119 396.8 0.2 3.2e-94 314.2 0.0 2.2 1 1 1 2 2 2 2 MCM P-loop domain MCM_OB PF17207.3 CDJ91532.1 - 7.2e-31 106.7 0.0 1.3e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CDJ91532.1 - 1.6e-22 79.7 0.7 3.8e-22 78.5 0.7 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 CDJ91532.1 - 2.4e-07 30.3 0.0 1.5e-06 27.8 0.0 2.2 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 CDJ91532.1 - 1.1e-06 29.1 0.0 3.3e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 CDJ91532.1 - 0.00098 19.1 0.0 0.011 15.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CDJ91532.1 - 0.0018 18.1 0.0 0.0069 16.2 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RcpC PF16976.5 CDJ91532.1 - 0.022 14.8 0.0 0.067 13.2 0.0 1.9 1 0 0 1 1 1 0 Flp pilus assembly protein RcpC/CpaB Sigma54_activat PF00158.26 CDJ91532.1 - 0.023 14.4 0.0 0.092 12.5 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.6 CDJ91532.1 - 0.12 12.7 0.3 1.1 9.6 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain MCM_bind PF09739.9 CDJ91532.1 - 0.41 9.0 3.6 1.7 7.0 0.2 2.4 3 0 0 3 3 3 0 Mini-chromosome maintenance replisome factor 7tm_1 PF00001.21 CDJ91533.1 - 0.00027 20.3 9.8 0.0011 18.3 9.8 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Sre PF03125.18 CDJ91533.1 - 0.0015 17.7 2.1 0.0015 17.7 2.1 2.0 2 0 0 2 2 2 2 C. elegans Sre G protein-coupled chemoreceptor DUF5373 PF17343.2 CDJ91533.1 - 0.06 13.2 6.3 0.057 13.3 5.6 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5373) AA_permease PF00324.21 CDJ91533.1 - 0.16 10.5 7.6 0.18 10.3 7.6 1.1 1 0 0 1 1 1 0 Amino acid permease UPF0182 PF03699.13 CDJ91533.1 - 0.3 9.2 1.8 0.39 8.8 1.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Serinc PF03348.15 CDJ91533.1 - 0.62 8.9 6.2 0.56 9.1 5.1 1.4 1 1 0 1 1 1 0 Serine incorporator (Serinc) FixS PF03597.15 CDJ91533.1 - 4.6 7.0 10.6 0.12 12.1 1.8 2.5 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type PGK PF00162.19 CDJ91534.1 - 0.049 12.6 0.1 0.052 12.5 0.1 1.1 1 0 0 1 1 1 0 Phosphoglycerate kinase Ion_trans_2 PF07885.16 CDJ91535.1 - 5e-31 106.5 25.5 2.4e-17 62.7 3.0 2.7 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CDJ91535.1 - 2.3e-05 23.8 16.8 0.0026 17.0 0.6 2.3 2 0 0 2 2 2 2 Ion transport protein Catalase-rel PF06628.12 CDJ91535.1 - 0.062 13.5 3.4 30 4.9 0.1 4.0 4 0 0 4 4 4 0 Catalase-related immune-responsive NADH_Oxid_Nqo15 PF11497.8 CDJ91535.1 - 0.16 12.0 0.0 0.59 10.2 0.0 1.9 1 1 1 2 2 2 0 NADH-quinone oxidoreductase chain 15 Cytochrome-c551 PF10643.9 CDJ91535.1 - 0.17 11.4 5.8 2.2 7.8 0.3 2.4 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 zf-RING_2 PF13639.6 CDJ91536.1 - 2.8e-12 46.8 9.5 5.7e-12 45.8 9.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CDJ91536.1 - 1.3e-10 40.8 5.0 2.6e-10 39.8 5.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 CDJ91536.1 - 3.3e-07 30.1 8.5 7.1e-07 29.0 8.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ91536.1 - 6.4e-07 29.1 9.2 1.4e-06 28.0 9.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDJ91536.1 - 8.6e-06 25.9 12.3 5.5e-05 23.4 12.3 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CDJ91536.1 - 2.9e-05 23.8 6.7 6.4e-05 22.7 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ91536.1 - 6.5e-05 22.8 7.3 0.00012 21.9 7.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain PA PF02225.22 CDJ91536.1 - 7.4e-05 22.7 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-ANAPC11 PF12861.7 CDJ91536.1 - 0.00051 20.0 1.6 0.001 19.1 1.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CDJ91536.1 - 0.002 18.1 7.9 0.0053 16.7 7.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CDJ91536.1 - 0.0027 17.5 6.6 0.0065 16.3 6.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF4432 PF14486.6 CDJ91536.1 - 0.0038 16.1 0.0 0.0058 15.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4432) Zn_ribbon_17 PF17120.5 CDJ91536.1 - 0.039 13.6 4.3 0.084 12.5 4.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type UvrD_C PF13361.6 CDJ91536.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PHD PF00628.29 CDJ91536.1 - 0.85 9.6 7.0 1.7 8.6 7.0 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3H2C3 PF17122.5 CDJ91536.1 - 1.1 9.4 6.1 4.2 7.5 6.1 2.1 1 0 0 1 1 1 0 Zinc-finger zf-RING_4 PF14570.6 CDJ91536.1 - 1.7 8.5 8.2 3.8 7.4 8.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 CDJ91536.1 - 2.6 8.4 6.7 6 7.3 6.7 1.7 1 0 0 1 1 1 0 RING-like domain DUF1985 PF09331.11 CDJ91538.1 - 0.088 12.8 0.0 0.21 11.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1985) BRICHOS PF04089.14 CDJ91538.1 - 0.11 12.7 0.1 3.9 7.8 0.1 2.2 1 1 0 1 1 1 0 BRICHOS domain Mtp PF03821.16 CDJ91539.1 - 0.016 14.8 4.1 0.042 13.4 4.2 1.7 1 1 0 1 1 1 0 Golgi 4-transmembrane spanning transporter UCH PF00443.29 CDJ91541.1 - 2.1e-32 112.7 0.3 4e-32 111.7 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Iso_dh PF00180.20 CDJ91542.1 - 5.3e-77 259.3 0.0 6.9e-77 258.9 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phe_ZIP PF08916.11 CDJ91542.1 - 0.073 13.8 0.2 6.7 7.5 0.0 2.5 2 0 0 2 2 2 0 Phenylalanine zipper NTP_transf_6 PF06042.11 CDJ91542.1 - 0.091 12.6 0.0 0.24 11.2 0.0 1.6 2 0 0 2 2 2 0 Nucleotidyltransferase Sulfotransfer_2 PF03567.14 CDJ91543.1 - 1.4e-25 90.7 0.6 2e-25 90.2 0.6 1.1 1 0 0 1 1 1 1 Sulfotransferase family OEP PF02321.18 CDJ91543.1 - 0.058 13.2 0.3 0.1 12.4 0.3 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein Kunitz_BPTI PF00014.23 CDJ91544.1 - 8.2e-127 413.4 82.6 4.3e-17 62.1 1.4 9.6 10 0 0 10 10 10 8 Kunitz/Bovine pancreatic trypsin inhibitor domain Lustrin_cystein PF14625.6 CDJ91544.1 - 5.2e-63 209.2 119.7 3.2e-09 37.0 4.7 9.8 8 1 0 8 8 8 8 Lustrin, cysteine-rich repeated domain SWIRM PF04433.17 CDJ91544.1 - 0.6 10.5 3.0 26 5.2 0.0 4.1 5 0 0 5 5 5 0 SWIRM domain CAMSAP_CKK PF08683.11 CDJ91545.1 - 3.4e-43 146.6 0.0 5.8e-43 145.8 0.0 1.4 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated CAMSAP_CH PF11971.8 CDJ91545.1 - 4e-25 87.5 0.2 9.7e-25 86.2 0.2 1.6 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.31 CDJ91545.1 - 0.038 14.2 0.1 0.35 11.1 0.1 2.5 3 0 0 3 3 3 0 Calponin homology (CH) domain Thioredoxin_4 PF13462.6 CDJ91545.1 - 1.4 9.1 6.3 15 5.7 4.4 2.6 2 0 0 2 2 2 0 Thioredoxin HMMR_N PF15905.5 CDJ91546.1 - 0.0019 17.8 13.3 0.0019 17.8 13.3 8.8 6 3 2 8 8 8 4 Hyaluronan mediated motility receptor N-terminal GRIP PF01465.20 CDJ91546.1 - 0.0079 16.1 0.0 0.03 14.2 0.0 2.1 1 0 0 1 1 1 1 GRIP domain ZapB PF06005.12 CDJ91546.1 - 0.012 16.1 5.3 0.012 16.1 5.3 13.3 10 3 3 13 13 13 0 Cell division protein ZapB bZIP_1 PF00170.21 CDJ91546.1 - 0.063 13.4 0.1 0.063 13.4 0.1 11.4 11 1 1 12 12 12 0 bZIP transcription factor Tubulin PF00091.25 CDJ91547.1 - 1.3e-69 234.4 0.0 2.1e-69 233.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDJ91547.1 - 4.4e-43 146.4 0.1 6.9e-43 145.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CDJ91547.1 - 0.00013 22.3 0.0 0.00037 20.8 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CDJ91547.1 - 0.007 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CDJ91547.1 - 0.02 14.1 0.1 0.043 13.0 0.0 1.5 2 0 0 2 2 2 0 Tubulin like Glycos_transf_1 PF00534.20 CDJ91548.1 - 2.3e-22 79.3 0.0 3.7e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CDJ91548.1 - 6e-14 52.4 0.1 1e-13 51.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 CDJ91548.1 - 1.6e-09 38.3 0.0 2.8e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CDJ91548.1 - 1.2e-05 25.9 0.0 1.8e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Guanylate_cyc PF00211.20 CDJ91549.1 - 3e-52 176.9 0.0 1.1e-49 168.6 0.0 2.7 3 0 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain Pkinase PF00069.25 CDJ91549.1 - 2.2e-22 79.7 0.0 3.9e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ91549.1 - 1.2e-20 73.9 0.0 2.1e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ANF_receptor PF01094.28 CDJ91549.1 - 2.7e-05 23.5 0.2 0.00015 21.0 0.2 2.0 1 1 0 1 1 1 1 Receptor family ligand binding region HNOBA PF07701.14 CDJ91549.1 - 0.011 15.1 1.1 0.018 14.5 1.1 1.2 1 0 0 1 1 1 0 Heme NO binding associated Peripla_BP_6 PF13458.6 CDJ91549.1 - 0.024 14.3 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein DUF573 PF04504.14 CDJ91549.1 - 0.2 12.3 0.5 2.4 8.9 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF573 PTP_tm PF18861.1 CDJ91549.1 - 0.4 10.6 1.6 0.74 9.8 1.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J 7tm_1 PF00001.21 CDJ91551.1 - 4.2e-06 26.3 25.0 2.7e-05 23.6 6.6 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) NIF PF03031.18 CDJ91551.1 - 0.027 14.3 0.1 0.052 13.3 0.1 1.5 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase PHO4 PF01384.20 CDJ91551.1 - 0.26 10.3 1.0 0.41 9.7 1.0 1.4 1 0 0 1 1 1 0 Phosphate transporter family MOLO1 PF17175.4 CDJ91552.1 - 1.2e-27 96.4 0.3 2.1e-27 95.6 0.3 1.4 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 LRR19-TM PF15176.6 CDJ91552.1 - 1.8 8.6 4.0 69 3.5 0.0 2.7 2 1 0 2 2 2 0 Leucine-rich repeat family 19 TM domain Lipase_3 PF01764.25 CDJ91553.1 - 3.9e-24 85.1 0.0 7.3e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 CDJ91553.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) ECH_1 PF00378.20 CDJ91554.1 - 1.8e-36 125.7 0.0 2.1e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CDJ91554.1 - 3.2e-20 72.9 0.0 3.8e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Kinesin PF00225.23 CDJ91555.1 - 3.2e-93 312.3 2.0 3.2e-93 312.3 2.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ91555.1 - 9.4e-20 71.1 0.1 9.4e-20 71.1 0.1 3.0 4 0 0 4 4 4 1 Microtubule binding Lzipper-MIP1 PF14389.6 CDJ91555.1 - 0.0039 17.5 1.9 0.0039 17.5 1.9 2.4 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 PBP-Tp47_a PF14889.6 CDJ91555.1 - 0.038 13.6 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a LPP PF04728.13 CDJ91555.1 - 0.039 14.4 6.6 3.1 8.3 0.9 3.2 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DUF4093 PF13331.6 CDJ91555.1 - 0.26 11.7 4.9 8.8 6.8 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4093) ATPase PF06745.13 CDJ91555.1 - 0.68 9.2 4.3 0.32 10.3 1.3 2.0 2 0 0 2 2 2 0 KaiC Peptidase_S49_N PF08496.10 CDJ91555.1 - 2.2 8.4 0.0 2.2 8.4 0.0 3.2 2 1 1 3 3 3 0 Peptidase family S49 N-terminal XhlA PF10779.9 CDJ91555.1 - 3 8.1 8.1 0.57 10.4 2.5 2.8 2 0 0 2 2 2 0 Haemolysin XhlA DUF1664 PF07889.12 CDJ91555.1 - 5.8 7.0 8.9 1.8 8.6 2.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) RA PF00788.23 CDJ91556.1 - 0.00012 22.6 0.4 0.00049 20.7 0.4 2.1 1 1 0 1 1 1 1 Ras association (RalGDS/AF-6) domain BEN PF10523.9 CDJ91556.1 - 0.097 12.9 0.1 0.28 11.4 0.1 1.8 1 0 0 1 1 1 0 BEN domain DUF4579 PF15158.6 CDJ91556.1 - 0.12 12.1 0.3 0.25 11.1 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4579) FARP PF01581.16 CDJ91558.1 - 0.092 13.3 6.3 1.4e+02 3.7 0.1 4.4 4 0 0 4 4 4 0 FMRFamide related peptide family DUF1930 PF09122.10 CDJ91558.1 - 0.16 11.9 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1930) Prolactin_RP PF15172.6 CDJ91558.1 - 5.8 6.6 12.2 22 4.7 0.1 3.9 1 1 3 4 4 4 0 Prolactin-releasing peptide DUF21 PF01595.20 CDJ91559.1 - 4.7e-27 94.8 0.1 8e-27 94.1 0.1 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CDJ91559.1 - 1.4e-07 31.8 2.0 0.00039 20.8 0.1 2.8 2 0 0 2 2 2 2 CBS domain Cupin_2 PF07883.11 CDJ91559.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Ras PF00071.22 CDJ91561.1 - 1.2e-50 171.3 2.6 2.1e-50 170.5 0.0 2.6 3 1 0 3 3 3 1 Ras family Roc PF08477.13 CDJ91561.1 - 4.5e-31 107.6 0.0 6.3e-30 103.9 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ91561.1 - 1.9e-16 60.0 1.9 2.7e-16 59.5 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family EF-hand_1 PF00036.32 CDJ91561.1 - 1.1e-12 46.5 0.5 4e-07 29.1 0.8 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CDJ91561.1 - 2.5e-12 47.1 2.6 1.2e-08 35.3 0.2 3.2 2 1 1 3 3 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ91561.1 - 9.5e-11 40.7 0.1 5.1e-05 22.9 0.2 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CDJ91561.1 - 3.3e-09 36.4 0.4 1.3e-07 31.4 0.4 2.8 1 1 1 2 2 2 1 EF-hand domain pair MMR_HSR1 PF01926.23 CDJ91561.1 - 1.3e-07 31.7 0.0 5.1e-07 29.8 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_5 PF13202.6 CDJ91561.1 - 6.7e-06 25.4 1.6 1.7e-05 24.1 0.3 2.4 2 0 0 2 2 2 1 EF hand GTP_EFTU PF00009.27 CDJ91561.1 - 3.6e-05 23.4 0.0 3.6e-05 23.4 0.0 2.9 2 2 1 3 3 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CDJ91561.1 - 0.00017 21.0 0.7 0.0014 18.1 0.0 2.6 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region PAXIP1_C PF15364.6 CDJ91561.1 - 0.0046 17.3 8.9 0.011 16.1 8.9 1.6 1 0 0 1 1 1 1 PAXIP1-associated-protein-1 C term PTIP binding protein DUF4090 PF13319.6 CDJ91561.1 - 0.16 12.2 5.0 0.4 10.9 0.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4090) DASH_Dam1 PF08653.10 CDJ91561.1 - 0.2 11.5 5.1 0.76 9.6 0.5 2.8 2 0 0 2 2 2 0 DASH complex subunit Dam1 AAA_33 PF13671.6 CDJ91561.1 - 0.75 10.0 0.0 0.75 10.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 CDJ91561.1 - 0.83 9.5 5.4 0.94 9.4 0.0 3.2 4 0 0 4 4 4 0 RsgA GTPase DUF5082 PF16888.5 CDJ91561.1 - 1.6 9.0 18.8 0.78 10.0 8.3 2.9 2 1 1 3 3 2 0 Domain of unknown function (DUF5082) KASH_CCD PF14662.6 CDJ91561.1 - 2.5 7.9 41.6 6.7 6.5 1.1 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DASH_Duo1 PF08651.10 CDJ91561.1 - 2.8 7.8 8.3 12 5.8 2.6 3.0 3 0 0 3 3 3 0 DASH complex subunit Duo1 Homeodomain PF00046.29 CDJ91562.1 - 4.2e-22 77.8 5.3 6.1e-22 77.2 5.3 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ91562.1 - 0.026 14.4 0.1 0.062 13.2 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain SCHIP-1 PF10148.9 CDJ91562.1 - 0.026 14.1 2.3 0.033 13.8 2.3 1.2 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 EzrA PF06160.12 CDJ91562.1 - 0.055 11.6 0.3 0.068 11.3 0.3 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA GAIN_A PF18619.1 CDJ91562.1 - 0.074 13.3 0.2 0.26 11.5 0.1 1.9 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Homez PF11569.8 CDJ91562.1 - 0.1 12.1 1.4 0.27 10.7 1.4 1.7 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez MTP18 PF10558.9 CDJ91563.1 - 1.2e-19 70.9 2.7 3e-17 63.1 2.7 2.0 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) MFS_1 PF07690.16 CDJ91564.1 - 1.3e-44 152.6 51.3 5.4e-44 150.5 28.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ91564.1 - 1.8e-10 40.3 20.5 6.3e-10 38.5 20.5 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 CDJ91564.1 - 0.0051 15.4 1.2 0.0051 15.4 1.2 3.7 2 1 0 2 2 2 1 MFS/sugar transport protein DUF2976 PF11190.8 CDJ91564.1 - 0.47 10.3 6.6 0.6 10.0 1.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) DUF2953 PF11167.8 CDJ91564.1 - 0.66 10.1 2.8 5.8 7.1 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2953) Ni_hydr_CYTB PF01292.20 CDJ91564.1 - 4.5 6.8 8.1 0.23 11.1 0.6 2.4 3 0 0 3 3 3 0 Prokaryotic cytochrome b561 Elongin_A PF06881.11 CDJ91566.1 - 2.6e-18 66.5 0.9 2.6e-18 66.5 0.9 2.4 2 1 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Med26 PF08711.11 CDJ91566.1 - 3.3e-09 36.6 0.0 8.6e-09 35.3 0.0 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TAFII55_N PF04658.13 CDJ91567.1 - 1.5e-50 171.1 0.7 1.9e-50 170.7 0.7 1.2 1 0 0 1 1 1 1 TAFII55 protein conserved region 7tm_1 PF00001.21 CDJ91568.1 - 1.8e-38 132.4 9.3 2.1e-38 132.1 9.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 CDJ91568.1 - 1.8e-05 24.2 7.1 8e-05 22.1 7.1 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 CDJ91568.1 - 0.055 13.2 1.1 0.096 12.4 1.1 1.5 1 0 0 1 1 1 0 Olfactory receptor 7TM_GPCR_Srx PF10328.9 CDJ91568.1 - 0.66 9.6 9.9 0.095 12.3 5.4 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx RVT_1 PF00078.27 CDJ91569.1 - 5.8e-37 127.4 0.0 1.7e-36 125.9 0.0 1.6 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RBD-FIP PF09457.10 CDJ91569.1 - 0.29 11.1 3.8 1.7 8.6 0.1 2.9 3 0 0 3 3 3 0 FIP domain Sulfatase PF00884.23 CDJ91570.1 - 3.9e-51 174.3 0.0 5.2e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 CDJ91570.1 - 1.1e-23 84.3 0.0 2.1e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.17 CDJ91570.1 - 0.00081 18.1 0.0 0.001 17.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 CDJ91570.1 - 0.007 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PAN_1 PF00024.26 CDJ91571.1 - 0.07 13.1 0.2 0.099 12.6 0.2 1.3 1 0 0 1 1 1 0 PAN domain ANF_receptor PF01094.28 CDJ91572.1 - 5.7e-24 84.9 0.0 6.5e-23 81.4 0.0 1.9 1 1 0 1 1 1 1 Receptor family ligand binding region DUF148 PF02520.17 CDJ91573.1 - 5.3e-16 58.7 9.0 5.9e-16 58.5 9.0 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF148 Apolipoprotein PF01442.18 CDJ91573.1 - 0.00032 20.6 7.9 0.015 15.2 3.1 2.0 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain FAM184 PF15665.5 CDJ91573.1 - 0.00038 20.3 2.8 0.00047 20.0 2.8 1.0 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B Lipase_chap PF03280.14 CDJ91573.1 - 0.00039 20.4 12.5 0.039 13.9 2.3 2.1 1 1 1 2 2 2 2 Proteobacterial lipase chaperone protein ApoLp-III PF07464.11 CDJ91573.1 - 0.0022 18.1 7.7 0.0029 17.7 7.7 1.2 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) Remorin_C PF03763.13 CDJ91573.1 - 0.0024 17.7 3.8 0.0031 17.4 3.8 1.2 1 0 0 1 1 1 1 Remorin, C-terminal region DUF3987 PF13148.6 CDJ91573.1 - 0.059 12.4 5.6 0.072 12.1 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ECH_2 PF16113.5 CDJ91573.1 - 0.068 12.7 3.1 0.077 12.5 3.1 1.0 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase TssO PF17561.2 CDJ91573.1 - 0.14 12.3 0.3 0.19 11.8 0.2 1.3 1 1 0 1 1 1 0 Type VI secretion system, TssO FUSC PF04632.12 CDJ91573.1 - 0.2 10.1 3.8 0.23 9.9 3.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Lant_dehydr_C PF14028.6 CDJ91573.1 - 0.29 10.6 2.3 0.36 10.3 2.3 1.1 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term OmpH PF03938.14 CDJ91573.1 - 1.6 9.1 13.1 4 7.8 13.1 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Lig_chan PF00060.26 CDJ91574.1 - 3.8e-44 150.1 0.5 5.5e-44 149.6 0.5 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 CDJ91574.1 - 3.8e-34 117.3 0.0 6.1e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 CDJ91574.1 - 2.2e-23 82.9 0.0 3.5e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Ion_trans_2 PF07885.16 CDJ91574.1 - 0.012 15.6 0.3 0.012 15.6 0.3 2.2 2 0 0 2 2 2 0 Ion channel LEA_4 PF02987.16 CDJ91575.1 - 3.5e-05 23.8 16.5 0.00038 20.5 6.1 2.3 2 0 0 2 2 2 2 Late embryogenesis abundant protein Apolipoprotein PF01442.18 CDJ91575.1 - 0.0004 20.3 0.5 0.00059 19.8 0.5 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 CDJ91575.1 - 0.0047 17.4 9.0 0.076 13.6 1.2 2.1 1 1 1 2 2 2 2 YtxH-like protein DUF883 PF05957.13 CDJ91575.1 - 0.011 16.3 5.1 0.047 14.3 0.7 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) KMP11 PF03037.16 CDJ91575.1 - 0.033 15.0 0.6 0.2 12.5 0.4 1.9 1 1 1 2 2 2 0 Kinetoplastid membrane protein 11 Sec16_N PF12935.7 CDJ91575.1 - 0.04 14.1 0.5 0.047 13.9 0.5 1.0 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 N-terminus Phasin PF05597.11 CDJ91575.1 - 0.048 13.7 4.5 0.23 11.5 4.5 1.9 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Perilipin PF03036.16 CDJ91575.1 - 0.068 12.2 1.2 0.11 11.6 1.1 1.4 1 1 0 1 1 1 0 Perilipin family ApoO PF09769.9 CDJ91575.1 - 0.15 12.0 0.5 1.7 8.6 0.1 2.0 1 1 1 2 2 2 0 Apolipoprotein O Ribosomal_60s PF00428.19 CDJ91575.1 - 0.4 11.3 6.9 0.56 10.8 6.9 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein HSP9_HSP12 PF04119.12 CDJ91575.1 - 0.57 10.6 5.1 13 6.2 4.5 3.0 1 1 1 2 2 2 0 Heat shock protein 9/12 CBFD_NFYB_HMF PF00808.23 CDJ91575.1 - 0.66 10.3 3.3 3.5 8.0 0.1 2.8 1 1 1 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-NOSIP PF15906.5 CDJ91575.1 - 1.2 9.3 5.2 1.4 9.1 0.4 2.7 2 1 1 3 3 3 0 Zinc-finger of nitric oxide synthase-interacting protein Apolipoprotein PF01442.18 CDJ91576.1 - 0.0001 22.3 0.9 0.00015 21.7 0.9 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 CDJ91576.1 - 0.0014 19.2 4.7 0.015 15.9 0.4 2.0 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 CDJ91576.1 - 0.0017 18.8 6.8 1 10.0 6.8 2.2 1 1 0 1 1 1 1 YtxH-like protein LEA_4 PF02987.16 CDJ91576.1 - 0.0044 17.1 5.0 0.0044 17.1 5.0 2.6 1 1 1 2 2 2 1 Late embryogenesis abundant protein Perilipin PF03036.16 CDJ91576.1 - 0.032 13.2 1.6 0.059 12.4 1.4 1.5 1 1 1 2 2 2 0 Perilipin family PE PF00934.20 CDJ91576.1 - 0.036 14.4 1.3 0.045 14.1 1.3 1.2 1 0 0 1 1 1 0 PE family DUF3972 PF13118.6 CDJ91576.1 - 0.037 14.5 0.1 0.041 14.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) Phasin PF05597.11 CDJ91576.1 - 0.064 13.3 3.5 0.12 12.4 2.7 1.6 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Synuclein PF01387.17 CDJ91576.1 - 0.12 12.6 6.3 0.58 10.4 4.7 2.1 1 1 1 2 2 2 0 Synuclein DAGK_prokar PF01219.19 CDJ91576.1 - 0.22 11.3 0.5 2.5 8.0 0.1 2.3 1 1 2 3 3 3 0 Prokaryotic diacylglycerol kinase DUF4407 PF14362.6 CDJ91576.1 - 1.2 8.5 4.8 1.3 8.3 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LEA_4 PF02987.16 CDJ91577.1 - 5.5e-06 26.4 5.1 0.00022 21.2 0.7 2.4 1 1 2 3 3 3 3 Late embryogenesis abundant protein YtxH PF12732.7 CDJ91577.1 - 0.00021 21.8 6.0 0.0047 17.4 6.0 2.1 1 1 0 1 1 1 1 YtxH-like protein Apolipoprotein PF01442.18 CDJ91577.1 - 0.00058 19.8 6.1 0.00076 19.4 6.1 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 CDJ91577.1 - 0.0038 17.8 8.2 0.019 15.5 8.2 1.9 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF883) Oleosin PF01277.17 CDJ91577.1 - 0.14 12.0 5.3 0.87 9.4 0.3 2.1 1 1 1 2 2 2 0 Oleosin PHA_gran_rgn PF09650.10 CDJ91577.1 - 0.45 10.8 4.5 0.69 10.2 0.6 2.4 1 1 2 3 3 3 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) MT0933_antitox PF14013.6 CDJ91577.1 - 1.9 8.8 10.8 53 4.2 10.8 2.3 1 1 0 1 1 1 0 MT0933-like antitoxin protein Fasciclin PF02469.22 CDJ91578.1 - 2.2e-13 50.6 0.0 2.6e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain AhpC-TSA_2 PF13911.6 CDJ91579.1 - 6.4e-12 45.6 0.0 1.2e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 CDJ91579.1 - 0.00031 20.6 0.0 0.00048 20.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDJ91579.1 - 0.0048 16.6 0.0 0.012 15.3 0.0 1.6 2 0 0 2 2 2 1 Redoxin Thiolase_N PF00108.23 CDJ91580.1 - 2.3e-77 259.9 1.3 3.9e-77 259.1 1.3 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CDJ91580.1 - 2.9e-39 133.5 0.3 2.4e-38 130.6 0.1 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CDJ91580.1 - 0.0002 21.0 1.3 0.24 10.9 0.2 2.9 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CDJ91580.1 - 0.00022 21.0 1.6 0.004 17.0 0.1 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 CDJ91580.1 - 0.0024 16.6 0.5 0.0041 15.9 0.5 1.2 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) Thiolase_N PF00108.23 CDJ91581.1 - 3.8e-89 298.5 4.3 5e-89 298.1 4.3 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CDJ91581.1 - 3e-41 139.9 1.9 2.1e-40 137.2 0.1 2.7 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CDJ91581.1 - 1.6e-05 24.6 1.1 1.6e-05 24.6 1.1 2.2 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CDJ91581.1 - 0.0052 16.6 2.9 0.15 11.9 0.2 3.0 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ArfGap PF01412.18 CDJ91582.1 - 4.8e-38 129.8 0.0 1.1e-37 128.7 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 CDJ91582.1 - 5.8e-38 130.9 1.6 8.8e-38 130.4 1.6 1.2 1 0 0 1 1 1 1 BAR domain of APPL family Ank_2 PF12796.7 CDJ91582.1 - 7.3e-23 81.0 5.7 1.6e-12 47.8 0.5 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) PH PF00169.29 CDJ91582.1 - 1.5e-16 60.8 0.0 3.1e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 PH domain Ank_5 PF13857.6 CDJ91582.1 - 1.2e-12 47.8 1.3 1.5e-06 28.3 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDJ91582.1 - 4.4e-12 46.3 0.1 2.8e-05 24.6 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CDJ91582.1 - 5.5e-12 45.6 6.0 0.0014 19.0 0.2 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 CDJ91582.1 - 4.4e-09 35.8 0.1 0.018 15.5 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat PH_11 PF15413.6 CDJ91582.1 - 0.011 16.1 0.2 0.29 11.6 0.1 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain Arfaptin PF06456.13 CDJ91582.1 - 0.1 12.1 0.3 0.7 9.4 0.3 2.1 1 1 0 1 1 1 0 Arfaptin-like domain zf-dskA_traR PF01258.17 CDJ91582.1 - 1.7 8.7 4.8 41 4.2 0.0 3.2 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger Ins_P5_2-kin PF06090.12 CDJ91583.1 - 6.6e-50 170.4 0.0 8.3e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase NAD_kinase PF01513.21 CDJ91584.1 - 3.3e-12 46.2 0.0 5.6e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase T3SS_ExsE PF18286.1 CDJ91584.1 - 0.15 12.0 0.2 0.55 10.2 0.0 2.0 2 0 0 2 2 2 0 Type III secretion system ExsE COesterase PF00135.28 CDJ91585.1 - 2.3e-28 99.4 0.2 2.8e-23 82.6 0.0 2.7 1 1 1 2 2 2 2 Carboxylesterase family ACBP PF00887.19 CDJ91586.1 - 1.5e-12 47.6 1.9 2.5e-12 46.8 0.6 1.8 1 1 0 2 2 2 1 Acyl CoA binding protein 2-Hacid_dh_C PF02826.19 CDJ91587.1 - 1.4e-62 210.2 0.1 3.1e-62 209.1 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CDJ91587.1 - 4.4e-34 117.0 0.8 6.8e-34 116.4 0.8 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CDJ91587.1 - 3.9e-06 27.1 1.8 1.3e-05 25.4 0.0 2.4 2 2 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 CDJ91587.1 - 0.00014 21.5 0.1 0.00044 19.8 0.0 1.9 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 CDJ91587.1 - 0.00016 21.8 2.4 0.0036 17.4 0.0 2.6 1 1 1 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox PF00070.27 CDJ91587.1 - 0.0024 18.4 0.9 0.94 10.1 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_C PF03720.15 CDJ91587.1 - 0.0027 18.1 0.5 0.014 15.8 0.0 2.3 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain TrkA_N PF02254.18 CDJ91587.1 - 0.013 15.7 0.4 0.051 13.8 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain F420_oxidored PF03807.17 CDJ91587.1 - 0.014 16.0 1.7 0.028 15.0 0.1 2.4 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent RVT_1 PF00078.27 CDJ91588.1 - 1.4e-16 60.7 0.0 2.2e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zinc_ribbon_4 PF13717.6 CDJ91588.1 - 0.075 13.0 0.1 0.18 11.7 0.1 1.7 1 0 0 1 1 1 0 zinc-ribbon domain AAA_12 PF13087.6 CDJ91589.1 - 1.7e-38 132.2 0.0 4e-38 131.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ91589.1 - 2.2e-26 93.2 0.0 7.9e-24 84.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ91589.1 - 4.6e-10 39.5 0.0 1.7e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CDJ91589.1 - 1.6e-08 35.0 0.0 3.1e-06 27.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Motile_Sperm PF00635.26 CDJ91589.1 - 1.5e-05 24.8 0.0 3.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF2075 PF09848.9 CDJ91589.1 - 8.5e-05 21.9 0.4 0.3 10.3 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 CDJ91589.1 - 0.0038 16.7 0.0 0.0076 15.7 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein UvrD-helicase PF00580.21 CDJ91589.1 - 0.0067 16.0 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_25 PF13481.6 CDJ91589.1 - 0.0073 15.9 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ91589.1 - 0.037 14.4 0.0 0.17 12.3 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain UvrD_C_2 PF13538.6 CDJ91589.1 - 0.04 13.7 0.1 0.1 12.5 0.1 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_5 PF07728.14 CDJ91589.1 - 0.14 12.1 0.0 0.54 10.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 CDJ91589.1 - 0.18 12.2 0.1 0.91 10.0 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPR_21 PF09976.9 CDJ91590.1 - 0.21 11.3 0.1 0.29 10.8 0.1 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain Dickkopf_N PF04706.12 CDJ91591.1 - 0.0083 16.6 37.6 0.23 12.0 0.6 5.2 5 0 0 5 5 5 3 Dickkopf N-terminal cysteine-rich region EB PF01683.18 CDJ91591.1 - 0.49 10.7 41.8 0.51 10.7 4.5 4.9 2 1 3 5 5 5 0 EB module Dickkopf_N PF04706.12 CDJ91592.1 - 0.0084 16.6 1.0 0.0084 16.6 1.0 4.4 4 0 0 4 4 4 3 Dickkopf N-terminal cysteine-rich region TIL PF01826.17 CDJ91592.1 - 0.04 14.2 4.4 0.04 14.2 4.4 4.7 3 1 1 4 4 4 0 Trypsin Inhibitor like cysteine rich domain TIL PF01826.17 CDJ91593.1 - 8.1e-08 32.4 17.2 8.1e-08 32.4 17.2 3.7 4 0 0 4 4 4 3 Trypsin Inhibitor like cysteine rich domain EFF-AFF PF14884.6 CDJ91594.1 - 6.3e-74 249.2 3.5 1.1e-73 248.3 3.5 1.3 1 1 0 1 1 1 1 Type I membrane glycoproteins cell-cell fusogen Ig_mannosidase PF17753.1 CDJ91594.1 - 0.22 11.3 0.4 0.64 9.8 0.0 1.9 2 0 0 2 2 2 0 Ig-fold domain DNTTIP1_dimer PF18192.1 CDJ91595.1 - 3.4e-24 85.0 0.2 6.4e-24 84.1 0.2 1.5 1 0 0 1 1 1 1 DNTTIP1 dimerisation domain AT_hook PF02178.19 CDJ91595.1 - 0.013 15.3 2.2 0.038 13.9 2.2 1.8 1 0 0 1 1 1 0 AT hook motif SNF PF00209.18 CDJ91596.1 - 4.2e-219 728.6 36.4 4.8e-219 728.4 36.4 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family VWA PF00092.28 CDJ91597.1 - 1.4e-38 132.9 0.3 2.3e-38 132.2 0.3 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CDJ91597.1 - 5.4e-16 59.2 0.0 1e-15 58.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-ANAPC11 PF12861.7 CDJ91597.1 - 0.0058 16.6 7.1 0.96 9.5 1.1 2.9 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger Ldl_recept_a PF00057.18 CDJ91597.1 - 0.012 15.8 2.4 5.5 7.3 0.2 2.8 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A PDH PF02153.17 CDJ91597.1 - 0.12 11.4 0.0 1.9 7.4 0.0 2.1 2 0 0 2 2 2 0 Prephenate dehydrogenase Fer4_8 PF13183.6 CDJ91597.1 - 0.13 12.7 1.3 13 6.3 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Homeodomain PF00046.29 CDJ91598.1 - 9.2e-22 76.7 2.3 9.2e-22 76.7 2.3 1.6 2 0 0 2 2 2 1 Homeodomain Seryl_tRNA_N PF02403.22 CDJ91599.1 - 0.012 15.8 0.9 0.018 15.3 0.9 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Uds1 PF15456.6 CDJ91599.1 - 0.06 13.5 2.4 0.1 12.8 2.4 1.4 1 0 0 1 1 1 0 Up-regulated During Septation Chromo PF00385.24 CDJ91600.1 - 0.00019 21.3 0.2 0.00034 20.5 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain NAPRTase_C PF17956.1 CDJ91600.1 - 0.056 13.9 0.0 0.061 13.8 0.0 1.4 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase C-terminal domain Glycos_transf_2 PF00535.26 CDJ91601.1 - 4.3e-28 98.2 0.1 3.8e-27 95.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CDJ91601.1 - 1.4e-16 60.9 0.2 2.3e-16 60.2 0.2 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 CDJ91601.1 - 1.2e-06 28.0 0.0 2.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CDJ91601.1 - 0.0089 15.5 0.0 0.028 13.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CDJ91601.1 - 0.073 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Glycosyl transferase family group 2 GARS_C PF02843.16 CDJ91601.1 - 0.083 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, C domain EMP24_GP25L PF01105.24 CDJ91602.1 - 7.7e-55 185.7 0.1 8.9e-55 185.5 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD adh_short PF00106.25 CDJ91603.1 - 8.6e-32 110.2 0.7 9.7e-24 83.9 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ91603.1 - 3.6e-20 72.5 0.1 9.2e-19 67.9 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ91603.1 - 3.2e-11 43.4 0.1 5.7e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDJ91603.1 - 1.1e-07 31.5 0.0 1.8e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 CDJ91603.1 - 0.00011 22.5 0.1 0.00078 19.7 0.1 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 CDJ91603.1 - 0.00085 18.8 0.0 0.0015 18.0 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 CDJ91603.1 - 0.0047 16.8 0.1 0.041 13.8 0.0 2.4 2 1 1 3 3 3 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CDJ91603.1 - 0.019 14.2 0.5 0.29 10.3 0.5 2.6 1 1 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.15 CDJ91603.1 - 0.034 13.3 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF4061 PF13270.6 CDJ91603.1 - 0.085 13.2 0.1 0.26 11.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) Pro_dh PF01619.18 CDJ91604.1 - 0.074 12.6 0.0 0.075 12.6 0.0 1.1 1 0 0 1 1 1 0 Proline dehydrogenase EGF_CA PF07645.15 CDJ91605.1 - 5.1e-29 100.2 122.1 2.1e-09 37.4 4.1 9.2 8 2 1 9 9 9 5 Calcium-binding EGF domain EGF_3 PF12947.7 CDJ91605.1 - 2.6e-21 75.5 110.3 2.7e-08 33.9 7.5 9.0 9 0 0 9 9 9 6 EGF domain cEGF PF12662.7 CDJ91605.1 - 6.4e-17 61.2 60.0 1.7e-05 24.6 4.6 8.7 8 0 0 8 8 8 7 Complement Clr-like EGF-like EGF PF00008.27 CDJ91605.1 - 1.8e-06 28.1 105.5 0.00054 20.2 6.0 9.8 9 1 0 9 9 9 5 EGF-like domain EGF_MSP1_1 PF12946.7 CDJ91605.1 - 4.6e-06 26.6 28.3 0.00041 20.3 5.4 8.1 8 0 0 8 8 8 4 MSP1 EGF domain 1 tRNA-synt_2 PF00152.20 CDJ91607.1 - 4.1e-76 256.0 0.0 5.3e-76 255.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CDJ91607.1 - 7.6e-09 35.4 1.2 1.6e-08 34.4 1.2 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CDJ91607.1 - 0.0014 18.2 0.1 0.58 9.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Collagen PF01391.18 CDJ91608.1 - 1.6e-19 69.4 121.0 3.2e-08 33.2 38.8 4.1 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ91608.1 - 6.1e-17 61.4 0.5 7.7e-17 61.1 0.5 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain COX14 PF14880.6 CDJ91608.1 - 0.012 15.5 1.9 0.018 14.8 1.9 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Collagen PF01391.18 CDJ91609.1 - 1.6e-26 91.9 85.9 1e-10 41.2 26.5 4.0 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Peptidase_M13_N PF05649.13 CDJ91611.1 - 1.3e-86 291.8 5.2 1.7e-86 291.3 5.2 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 CDJ91611.1 - 4.8e-72 241.9 1.2 5.2e-72 241.8 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M13 DUF4646 PF15496.6 CDJ91611.1 - 0.058 14.0 0.1 21 5.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4646) Peptidase_M13 PF01431.21 CDJ91612.1 - 7.6e-51 172.6 0.0 9e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 CDJ91613.1 - 1.7e-19 70.2 1.2 2e-19 70.0 1.2 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 CDJ91614.1 - 1.2e-50 172.0 0.0 1.5e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 Eapp_C PF10238.9 CDJ91615.1 - 8.7 6.4 8.7 5 7.2 2.9 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF4440 PF14534.6 CDJ91617.1 - 0.00097 19.5 0.0 0.0012 19.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF4440 PF14534.6 CDJ91618.1 - 4.4e-07 30.2 0.0 5.3e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 CDJ91618.1 - 0.00076 20.1 0.0 0.00092 19.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 CDJ91618.1 - 0.002 18.3 0.0 0.0025 18.1 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain Pro_isomerase PF00160.21 CDJ91619.1 - 3e-17 63.3 0.0 8e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 CDJ91619.1 - 3.2e-15 55.7 0.1 9.6e-15 54.2 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ91619.1 - 0.02 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) bZIP_2 PF07716.15 CDJ91621.1 - 0.00092 19.3 1.5 0.0018 18.3 1.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper CH PF00307.31 CDJ91622.1 - 5.5e-12 45.8 1.3 2.3e-11 43.9 0.0 2.6 3 1 1 4 4 4 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CDJ91622.1 - 1.2e-06 28.3 0.0 2.9e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain DMPK_coil PF08826.10 CDJ91622.1 - 0.00021 21.3 23.4 0.002 18.2 5.4 4.1 4 0 0 4 4 4 2 DMPK coiled coil domain like IFT57 PF10498.9 CDJ91622.1 - 0.0005 19.1 18.0 0.013 14.5 4.3 2.9 2 1 1 3 3 3 3 Intra-flagellar transport protein 57 DUF3037 PF11236.8 CDJ91622.1 - 0.015 15.8 1.1 0.015 15.8 1.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3037) Spc7 PF08317.11 CDJ91622.1 - 0.046 12.6 23.5 0.31 9.9 5.0 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4168 PF13767.6 CDJ91622.1 - 0.048 14.8 0.2 0.048 14.8 0.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) APG12 PF04110.13 CDJ91622.1 - 0.093 13.1 0.3 3.1 8.3 0.1 2.8 2 1 1 3 3 3 0 Ubiquitin-like autophagy protein Apg12 Fez1 PF06818.15 CDJ91622.1 - 0.46 10.9 21.1 3.7 7.9 19.2 2.5 1 1 1 2 2 2 0 Fez1 Prominin PF05478.11 CDJ91622.1 - 1.2 7.1 11.2 1.6 6.6 11.2 1.3 1 0 0 1 1 1 0 Prominin Tup_N PF08581.10 CDJ91622.1 - 1.4 9.3 18.9 0.18 12.1 5.2 3.6 2 1 1 3 3 3 0 Tup N-terminal Golgin_A5 PF09787.9 CDJ91622.1 - 1.4 8.3 27.2 0.96 8.9 12.4 2.2 1 1 0 2 2 2 0 Golgin subfamily A member 5 Plk4_PB2 PF18409.1 CDJ91622.1 - 2.7 8.7 6.5 2 9.1 0.8 2.7 2 2 1 3 3 3 0 Polo-like Kinase 4 Polo Box 2 FAM76 PF16046.5 CDJ91622.1 - 3 7.1 17.4 11 5.2 17.5 1.9 1 1 0 1 1 1 0 FAM76 protein PRKCSH-like PF12999.7 CDJ91622.1 - 5.7 6.7 11.5 0.72 9.6 0.7 2.8 2 1 1 3 3 3 0 Glucosidase II beta subunit-like Alpha-amylase PF00128.24 CDJ91623.1 - 6e-36 124.7 0.0 1.6e-35 123.3 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain SLC3A2_N PF16028.5 CDJ91623.1 - 6.8e-24 83.2 0.8 1.2e-23 82.4 0.8 1.4 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus Photo_RC PF00124.19 CDJ91623.1 - 0.011 14.9 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre protein Glyco_hydro_42C PF08533.10 CDJ91623.1 - 0.013 15.2 0.0 1.9 8.3 0.0 2.5 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain DnaT PF17948.1 CDJ91623.1 - 0.069 12.8 1.9 0.58 9.9 0.0 2.8 3 0 0 3 3 3 0 DnaT DNA-binding domain DUF2388 PF09498.10 CDJ91624.1 - 0.011 15.7 0.2 0.011 15.7 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) Nramp PF01566.18 CDJ91625.1 - 4.9e-118 394.2 11.0 4.9e-118 394.2 11.0 1.6 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein TPR_14 PF13428.6 CDJ91626.1 - 2.7e-14 52.6 18.0 1.4 9.9 0.0 11.6 9 4 4 13 13 12 3 Tetratricopeptide repeat TPR_15 PF13429.6 CDJ91626.1 - 1.1e-09 37.9 6.0 0.0093 15.2 0.0 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ91626.1 - 2.1e-08 34.3 6.3 0.16 12.2 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ91626.1 - 5.2e-07 30.1 0.1 3.8 8.1 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat Suf PF05843.14 CDJ91626.1 - 2.1e-06 28.0 16.8 0.15 12.0 1.1 6.3 3 2 2 6 6 6 2 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 CDJ91626.1 - 1.2e-05 25.3 17.5 1 9.3 0.0 7.3 6 2 1 7 7 7 3 Mad3/BUB1 homology region 1 TPR_8 PF13181.6 CDJ91626.1 - 2.4e-05 24.2 11.6 3.5 8.1 0.2 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ91626.1 - 3e-05 23.8 17.0 0.58 10.4 0.2 8.3 9 0 0 9 9 9 2 Tetratricopeptide repeat NRDE-2 PF08424.10 CDJ91626.1 - 0.00015 21.0 14.4 0.021 14.0 0.8 6.1 2 2 1 3 3 3 2 NRDE-2, necessary for RNA interference TPR_10 PF13374.6 CDJ91626.1 - 0.035 14.0 9.3 2.4 8.1 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ91626.1 - 0.078 13.0 2.4 8.4 6.7 0.1 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ91626.1 - 0.13 12.9 8.3 25 5.6 0.0 5.9 8 0 0 8 8 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ91626.1 - 0.42 11.1 9.0 31 5.3 0.0 6.4 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ91626.1 - 2.7 8.8 14.2 50 4.9 0.3 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat DEAD PF00270.29 CDJ91627.1 - 1.4e-31 109.6 0.0 6.1e-31 107.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ91627.1 - 2.8e-27 95.2 0.4 8.4e-27 93.7 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ91627.1 - 0.01 15.9 0.1 0.043 13.8 0.0 2.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit RVT_1 PF00078.27 CDJ91628.1 - 1.3e-24 87.0 0.0 1.6e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Comm PF15957.5 CDJ91631.1 - 0.0005 20.4 0.4 0.0005 20.4 0.4 1.8 2 0 0 2 2 2 1 Commissureless 7tm_1 PF00001.21 CDJ91631.1 - 0.0019 17.6 1.1 0.0022 17.4 0.2 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) FAM163 PF15069.6 CDJ91631.1 - 0.0028 18.1 0.6 0.0028 18.1 0.6 1.6 2 0 0 2 2 2 1 FAM163 family EphA2_TM PF14575.6 CDJ91631.1 - 0.0058 17.5 0.1 0.0058 17.5 0.1 1.6 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Adeno_E3 PF06040.11 CDJ91631.1 - 0.013 15.7 1.1 0.025 14.7 1.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 protein Synaptobrevin PF00957.21 CDJ91631.1 - 0.023 14.5 2.6 0.053 13.3 2.6 1.5 1 0 0 1 1 1 0 Synaptobrevin Protocadherin PF08374.11 CDJ91631.1 - 0.044 13.7 0.0 0.058 13.4 0.0 1.1 1 0 0 1 1 1 0 Protocadherin Prominin PF05478.11 CDJ91631.1 - 0.071 11.1 3.8 0.094 10.7 3.8 1.2 1 0 0 1 1 1 0 Prominin Myc_target_1 PF15179.6 CDJ91631.1 - 0.2 11.6 0.0 0.27 11.1 0.0 1.1 1 0 0 1 1 1 0 Myc target protein 1 Adeno_E3_CR2 PF02439.15 CDJ91631.1 - 2.1 8.1 14.9 0.81 9.5 10.8 2.1 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 LapA_dom PF06305.11 CDJ91631.1 - 7.1 6.5 6.4 0.93 9.4 1.3 2.1 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain FXa_inhibition PF14670.6 CDJ91632.1 - 0.0014 18.9 3.6 0.0014 18.9 3.6 4.5 4 1 0 4 4 4 2 Coagulation Factor Xa inhibitory site EGF_2 PF07974.13 CDJ91632.1 - 7.4 7.0 50.3 0.052 13.9 6.7 5.6 5 0 0 5 5 5 0 EGF-like domain TTR-52 PF01060.23 CDJ91633.1 - 6.9e-16 58.7 0.3 2.3e-15 57.1 0.0 1.8 2 0 0 2 2 2 1 Transthyretin-like family TTR-52 PF01060.23 CDJ91634.1 - 7.2e-29 100.3 1.1 9.1e-29 100.0 0.1 1.6 2 0 0 2 2 2 1 Transthyretin-like family bMG3 PF11974.8 CDJ91634.1 - 0.0078 16.2 0.0 0.0096 15.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-2-macroglobulin MG3 domain Rhabdo_ncap_2 PF03216.13 CDJ91635.1 - 1.1e-26 94.0 0.0 1.2e-26 93.9 0.0 1.0 1 0 0 1 1 1 1 Rhabdovirus nucleoprotein Rsc14 PF08586.10 CDJ91636.1 - 0.26 12.1 2.5 0.33 11.8 0.3 2.2 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit RNase_HII PF01351.18 CDJ91636.1 - 1.5 8.6 5.1 0.64 9.8 2.6 1.6 2 0 0 2 2 2 0 Ribonuclease HII Snapin_Pallidin PF14712.6 CDJ91636.1 - 1.6 9.2 10.0 1.2 9.6 3.3 2.6 1 1 1 2 2 2 0 Snapin/Pallidin 7TM_GPCR_Srv PF10323.9 CDJ91637.1 - 1.3e-18 67.4 13.1 1.4e-18 67.2 13.1 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Srg PF02118.21 CDJ91637.1 - 4.9e-12 46.1 17.0 5.6e-12 45.9 17.0 1.0 1 0 0 1 1 1 1 Srg family chemoreceptor 7tm_1 PF00001.21 CDJ91637.1 - 3.4e-06 26.6 11.9 5.5e-06 25.9 11.9 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CDJ91637.1 - 5.8e-06 26.1 14.7 7.7e-06 25.7 14.7 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srbc PF10316.9 CDJ91637.1 - 0.0016 18.0 3.1 0.0016 18.0 3.1 2.1 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc Adeno_E1B_55K PF01696.17 CDJ91637.1 - 0.16 10.6 0.4 0.22 10.2 0.4 1.1 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen DUF1129 PF06570.11 CDJ91637.1 - 4.7 6.6 9.2 0.071 12.6 1.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) ACBP PF00887.19 CDJ91638.1 - 9.9e-21 73.8 0.2 2.2e-20 72.6 0.2 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_4 PF13637.6 CDJ91638.1 - 2.3e-15 56.7 0.0 1.3e-14 54.4 0.0 2.3 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ91638.1 - 7.5e-14 51.6 0.1 2.1e-10 40.6 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CDJ91638.1 - 2e-13 50.1 0.0 6.2e-07 29.6 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 CDJ91638.1 - 2.5e-12 47.2 0.0 8.2e-12 45.5 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDJ91638.1 - 4.5e-12 45.0 0.0 3.1e-06 27.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Glutaredoxin PF00462.24 CDJ91639.1 - 9.7e-14 51.3 0.5 2e-13 50.3 0.5 1.5 1 1 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 CDJ91639.1 - 1.3e-05 25.5 0.8 2.1e-05 24.8 0.2 1.7 2 0 0 2 2 2 1 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 CDJ91639.1 - 0.012 16.0 0.0 0.016 15.6 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain MRP-63 PF14978.6 CDJ91642.1 - 1.2e-06 29.0 0.7 9.4e-05 23.0 0.7 2.2 1 1 0 1 1 1 1 Mitochondrial ribosome protein 63 Prp18 PF02840.15 CDJ91643.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Prp18 domain TFIIA PF03153.13 CDJ91644.1 - 4.7 7.1 11.5 5.3 6.9 11.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_LBD PF02931.23 CDJ91645.1 - 1e-20 74.1 1.9 1.4e-20 73.6 1.9 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain CIA30 PF08547.12 CDJ91645.1 - 0.079 13.0 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) DUF2070 PF09843.9 CDJ91645.1 - 0.6 8.3 9.2 0.76 8.0 9.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) FtsX PF02687.21 CDJ91645.1 - 3.2 8.3 8.1 0.59 10.6 3.8 1.9 2 0 0 2 2 2 0 FtsX-like permease family TrbC PF04956.13 CDJ91645.1 - 3.7 7.8 9.8 13 6.1 0.4 2.5 2 1 0 2 2 2 0 TrbC/VIRB2 family Glyco_hydro_20 PF00728.22 CDJ91646.1 - 1.5e-09 37.7 0.1 2.5e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain DUF4838 PF16126.5 CDJ91646.1 - 0.0068 15.8 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4838) TMIE PF16038.5 CDJ91647.1 - 4.7e-22 77.6 0.4 5.8e-22 77.3 0.4 1.2 1 0 0 1 1 1 1 TMIE protein Shisa PF13908.6 CDJ91647.1 - 0.0055 17.0 0.1 0.006 16.8 0.1 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Hum_adeno_E3A PF05393.11 CDJ91647.1 - 0.095 12.7 0.3 0.12 12.4 0.3 1.3 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein LapA_dom PF06305.11 CDJ91647.1 - 0.52 10.2 4.8 0.99 9.3 4.8 1.5 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain HECT PF00632.25 CDJ91648.1 - 1.6e-69 234.8 0.0 5e-69 233.1 0.0 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 CDJ91648.1 - 7.9e-05 22.1 0.5 0.0017 18.0 0.5 2.7 2 0 0 2 2 2 1 IQ calmodulin-binding motif CutC PF03932.14 CDJ91649.1 - 6e-21 74.8 0.2 2.5e-12 46.7 0.1 2.2 1 1 1 2 2 2 2 CutC family CUB PF00431.20 CDJ91649.1 - 6.3e-18 65.1 0.2 2e-12 47.4 0.0 3.0 3 0 0 3 3 3 2 CUB domain Laminin_EGF PF00053.24 CDJ91650.1 - 0.0034 17.5 6.8 0.11 12.7 6.8 2.3 1 1 0 1 1 1 1 Laminin EGF domain Fibrinogen_C PF00147.18 CDJ91651.1 - 1.9e-41 142.3 4.2 3.5e-41 141.4 4.2 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Lectin_C PF00059.21 CDJ91651.1 - 1e-11 45.5 7.7 1e-11 45.5 7.7 2.0 2 1 1 3 3 3 1 Lectin C-type domain UL45 PF05473.12 CDJ91651.1 - 0.14 11.8 3.0 0.22 11.2 3.0 1.2 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like PhnJ PF06007.11 CDJ91652.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ MRP_L53 PF10780.9 CDJ91653.1 - 4.2 7.6 5.8 9.1 6.5 1.4 2.3 2 0 0 2 2 2 0 39S ribosomal protein L53/MRP-L53 Reticulon PF02453.17 CDJ91655.1 - 2.7e-38 131.4 1.9 3.2e-38 131.2 1.9 1.1 1 0 0 1 1 1 1 Reticulon Polysacc_synt PF01943.17 CDJ91655.1 - 0.025 14.0 3.1 0.77 9.1 0.6 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF639 PF04842.12 CDJ91655.1 - 0.029 13.8 0.3 0.059 12.8 0.0 1.4 1 1 0 1 1 1 0 Plant protein of unknown function (DUF639) PRT_C PF08372.10 CDJ91655.1 - 0.08 12.7 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal BTB PF00651.31 CDJ91656.1 - 5.4e-26 91.0 0.6 3e-25 88.6 0.2 2.1 1 1 1 2 2 2 1 BTB/POZ domain Kelch_1 PF01344.25 CDJ91656.1 - 2.7e-25 87.7 3.4 5.5e-05 22.7 0.0 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 CDJ91656.1 - 7.6e-12 45.1 3.4 0.011 15.9 0.0 5.9 3 2 2 5 5 5 2 Kelch motif Kelch_3 PF13415.6 CDJ91656.1 - 5.9e-07 29.6 1.7 0.27 11.5 0.0 4.2 4 0 0 4 4 4 2 Galactose oxidase, central domain BACK PF07707.15 CDJ91656.1 - 0.00016 21.7 0.1 0.00031 20.8 0.1 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 CDJ91656.1 - 0.0063 16.5 4.9 14 5.8 0.0 5.3 5 1 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.25 CDJ91657.1 - 2.2e-28 97.5 7.6 1.3e-11 43.9 0.0 4.0 4 1 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 CDJ91657.1 - 2e-18 66.0 0.1 2e-07 31.1 0.0 3.1 1 1 2 3 3 3 3 Kelch motif Kelch_3 PF13415.6 CDJ91657.1 - 1.5e-10 41.1 1.1 0.011 16.0 0.1 3.2 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_2 PF07646.15 CDJ91657.1 - 4.8e-10 39.0 0.1 8.7e-05 22.3 0.0 2.8 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CDJ91657.1 - 1e-05 25.4 0.2 0.16 12.0 0.0 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 CDJ91657.1 - 3.8e-05 23.6 2.0 0.01 15.8 0.0 3.6 2 2 1 3 3 3 1 Galactose oxidase, central domain DUF547 PF04784.14 CDJ91658.1 - 1.5e-27 96.1 0.0 2.1e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Complex1_LYR PF05347.15 CDJ91658.1 - 0.062 13.4 0.2 0.16 12.0 0.1 1.8 2 0 0 2 2 2 0 Complex 1 protein (LYR family) GRAM PF02893.20 CDJ91659.1 - 3.1e-19 69.0 0.8 5.5e-19 68.1 0.8 1.4 1 0 0 1 1 1 1 GRAM domain CCDC53 PF10152.9 CDJ91660.1 - 0.012 16.1 2.4 0.012 16.1 2.4 3.5 2 1 0 2 2 1 0 Subunit CCDC53 of WASH complex NeA_P2 PF12312.8 CDJ91660.1 - 0.018 14.5 0.7 0.053 13.0 0.7 1.8 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein Peptidase_M32 PF02074.15 CDJ91660.1 - 0.045 12.5 3.5 0.078 11.7 3.5 1.2 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase SesA PF17107.5 CDJ91660.1 - 0.084 13.1 5.7 0.051 13.8 2.8 2.1 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Apolipoprotein PF01442.18 CDJ91660.1 - 0.25 11.2 8.3 1 9.2 8.2 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain FH2 PF02181.23 CDJ91660.1 - 0.56 9.3 10.0 2 7.4 1.4 2.4 1 1 1 2 2 2 0 Formin Homology 2 Domain DUF1759 PF03564.15 CDJ91660.1 - 0.59 10.1 2.9 1.2 9.1 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) Cbl_N PF02262.16 CDJ91660.1 - 0.63 10.1 6.4 6.8 6.7 1.2 2.3 1 1 1 2 2 2 0 CBL proto-oncogene N-terminal domain 1 NPV_P10 PF05531.12 CDJ91660.1 - 1.6 9.3 7.2 3.4 8.2 1.2 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 CDJ91660.1 - 2.6 7.3 8.4 4.3 6.6 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.11 CDJ91660.1 - 3.5 8.2 7.1 27 5.4 7.0 2.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Exonuc_VII_L PF02601.15 CDJ91660.1 - 3.6 7.1 9.0 8.7 5.8 9.0 1.7 1 0 0 1 1 1 0 Exonuclease VII, large subunit Baculo_PEP_C PF04513.12 CDJ91660.1 - 3.7 7.6 12.3 8.7 6.4 4.3 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LMBR1 PF04791.16 CDJ91660.1 - 4.3 6.1 6.7 6.1 5.6 6.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TPR_MLP1_2 PF07926.12 CDJ91660.1 - 5.4 7.1 15.2 0.97 9.5 3.1 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CLZ PF16526.5 CDJ91660.1 - 5.5 7.4 10.9 2.3 8.6 1.5 3.5 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ShK PF01549.24 CDJ91661.1 - 1.9e-08 34.7 9.2 3.4e-08 33.9 9.2 1.4 1 0 0 1 1 1 1 ShK domain-like FSA_C PF10479.9 CDJ91661.1 - 3.5 5.7 9.0 3.9 5.5 9.0 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Sporozoite_P67 PF05642.11 CDJ91661.1 - 6.2 4.8 8.6 7.4 4.5 8.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1664 PF07889.12 CDJ91662.1 - 0.11 12.5 0.0 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-CCHC PF00098.23 CDJ91662.1 - 0.42 10.8 5.6 1.6 9.0 5.6 2.0 1 0 0 1 1 1 0 Zinc knuckle CENP-H PF05837.12 CDJ91662.1 - 1.9 8.9 15.9 17 5.8 0.0 4.3 3 1 0 3 3 3 0 Centromere protein H (CENP-H) FapA PF03961.13 CDJ91662.1 - 3.9 6.0 7.1 2.1 6.9 0.2 2.3 2 0 0 2 2 2 0 Flagellar Assembly Protein A Peptidase_M13_N PF05649.13 CDJ91663.1 - 1.6e-13 51.1 0.4 2.3e-13 50.6 0.4 1.1 1 0 0 1 1 1 1 Peptidase family M13 GRAS PF03514.14 CDJ91663.1 - 0.068 12.1 0.0 0.096 11.6 0.0 1.1 1 0 0 1 1 1 0 GRAS domain family GIY-YIG PF01541.24 CDJ91664.1 - 0.081 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 GIY-YIG catalytic domain Myticin-prepro PF10690.9 CDJ91664.1 - 0.13 12.5 0.5 0.23 11.8 0.5 1.4 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel DDE_Tnp_1_7 PF13843.6 CDJ91665.1 - 2.1e-05 24.0 0.0 2.6e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 NKAIN PF05640.14 CDJ91666.1 - 1e-07 31.4 1.2 1.8e-07 30.6 1.2 1.3 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein Oxidored-like PF09791.9 CDJ91667.1 - 1.9e-08 33.8 3.2 2.9e-08 33.2 3.2 1.2 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF5522 PF17653.1 CDJ91667.1 - 0.01 15.8 1.6 0.017 15.1 1.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5522) RhoGAP PF00620.27 CDJ91668.1 - 1.3e-41 142.0 0.0 4.7e-41 140.1 0.0 2.0 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 CDJ91668.1 - 1.3e-14 54.2 3.2 1.3e-14 54.2 3.2 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain IL11 PF07400.11 CDJ91668.1 - 0.021 14.5 0.2 0.1 12.2 0.0 2.2 2 0 0 2 2 2 0 Interleukin 11 Vps55 PF04133.14 CDJ91669.1 - 2.5e-35 121.0 8.7 2.9e-35 120.7 8.7 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Bax1-I PF01027.20 CDJ91669.1 - 0.054 13.3 12.9 0.07 13.0 12.9 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF2070 PF09843.9 CDJ91669.1 - 4.2 5.6 8.5 4.8 5.4 8.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Met_synt_B12 PF02965.17 CDJ91671.1 - 5.3e-115 383.6 0.0 1e-114 382.6 0.0 1.5 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 CDJ91671.1 - 3.1e-76 256.7 0.0 6.2e-76 255.7 0.0 1.5 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 CDJ91671.1 - 4.2e-58 196.9 0.0 1.2e-57 195.4 0.0 1.8 2 0 0 2 2 2 1 Pterin binding enzyme B12-binding_2 PF02607.17 CDJ91671.1 - 1.2e-22 80.1 0.1 3.3e-22 78.7 0.1 1.8 1 0 0 1 1 1 1 B12 binding domain B12-binding PF02310.19 CDJ91671.1 - 2e-19 69.8 0.0 4e-18 65.6 0.2 2.7 2 0 0 2 2 2 1 B12 binding domain DUF5600 PF18150.1 CDJ91671.1 - 0.17 12.5 0.0 0.48 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5600) Plasmodium_Vir PF05795.11 CDJ91672.1 - 0.089 12.2 0.5 0.11 11.9 0.5 1.3 1 1 0 1 1 1 0 Plasmodium vivax Vir protein CSRNP_N PF16019.5 CDJ91672.1 - 0.15 12.0 5.5 1.5 8.7 0.8 2.1 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus DUF1129 PF06570.11 CDJ91672.1 - 0.21 11.1 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) PRELI PF04707.14 CDJ91673.1 - 1.4e-40 138.7 0.8 1.7e-40 138.4 0.8 1.1 1 0 0 1 1 1 1 PRELI-like family SQS_PSY PF00494.19 CDJ91674.1 - 8.9e-36 123.7 0.2 2e-35 122.5 0.2 1.6 1 0 0 1 1 1 1 Squalene/phytoene synthase MMgT PF10270.9 CDJ91674.1 - 6.1e-14 52.2 0.0 2e-13 50.5 0.0 1.9 1 0 0 1 1 1 1 Membrane magnesium transporter EB PF01683.18 CDJ91675.1 - 1.3e-19 70.2 94.4 8.4e-08 32.4 5.1 7.0 3 2 4 7 7 7 5 EB module EGF_MSP1_1 PF12946.7 CDJ91675.1 - 0.00055 19.9 11.2 0.00055 19.9 11.2 6.6 5 3 0 5 5 5 2 MSP1 EGF domain 1 Peptidase_M10 PF00413.24 CDJ91676.1 - 1.2e-42 145.5 3.3 1.5e-42 145.1 3.3 1.2 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.18 CDJ91676.1 - 4.8e-06 26.7 0.0 1.1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain DUF4953 PF16313.5 CDJ91676.1 - 0.00059 19.2 0.3 0.013 14.7 0.0 2.2 2 0 0 2 2 2 1 Met-zincin Reprolysin_4 PF13583.6 CDJ91676.1 - 0.0029 17.3 0.0 0.0051 16.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 CDJ91676.1 - 0.0058 17.2 0.1 0.012 16.1 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 CDJ91676.1 - 0.017 15.1 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 Peptidase_M66 PF10462.9 CDJ91676.1 - 0.028 13.4 0.1 0.043 12.8 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_5 PF13688.6 CDJ91676.1 - 0.035 14.2 0.1 0.065 13.4 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Metallopep PF12044.8 CDJ91676.1 - 0.072 11.7 0.5 0.13 10.9 0.1 1.5 2 0 0 2 2 2 0 Putative peptidase family Peptidase_M64 PF09471.10 CDJ91676.1 - 0.11 12.0 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 IgA Peptidase M64 Peptidase_M57 PF12388.8 CDJ91676.1 - 0.12 12.0 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase DUF45 PF01863.17 CDJ91676.1 - 0.12 12.3 1.2 1 9.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF45 UPF0054 PF02130.17 CDJ91676.1 - 0.13 12.1 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein family UPF0054 Astacin PF01400.24 CDJ91676.1 - 0.16 11.6 1.0 0.29 10.7 0.2 1.8 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) DEAD PF00270.29 CDJ91678.1 - 7.1e-21 74.7 0.0 9.9e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDJ91678.1 - 0.036 14.3 0.0 0.055 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Repressor_Mnt PF11423.8 CDJ91678.1 - 1.8 8.4 4.5 1.1 9.1 1.7 2.1 2 0 0 2 2 2 0 Regulatory protein Mnt Phage_holin_3_7 PF05449.11 CDJ91679.1 - 0.047 13.7 2.1 0.066 13.2 2.1 1.2 1 0 0 1 1 1 0 Putative 3TM holin, Phage_holin_3 DUF4459 PF14673.6 CDJ91682.1 - 0.037 14.0 0.1 0.039 13.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4459) Acyl_transf_3 PF01757.22 CDJ91683.1 - 1e-20 74.1 41.6 1e-20 74.1 41.6 2.0 2 0 0 2 2 2 1 Acyltransferase family DUF2085 PF09858.9 CDJ91683.1 - 0.036 14.6 0.1 0.036 14.6 0.1 3.9 3 1 2 5 5 5 0 Predicted membrane protein (DUF2085) Ferlin_C PF16165.5 CDJ91683.1 - 0.042 13.8 0.5 0.094 12.7 0.5 1.6 1 0 0 1 1 1 0 Ferlin C-terminus V-ATPase_C PF03223.15 CDJ91684.1 - 2.8e-55 188.2 1.6 3.1e-55 188.1 1.6 1.0 1 0 0 1 1 1 1 V-ATPase subunit C GAT PF03127.14 CDJ91684.1 - 0.013 15.8 1.4 0.13 12.6 0.1 2.4 2 1 0 2 2 2 0 GAT domain ATP-synt_C PF00137.21 CDJ91685.1 - 3e-35 120.3 35.3 2.7e-22 78.9 13.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CrgA PF06781.12 CDJ91685.1 - 0.25 11.4 3.0 0.59 10.2 0.5 2.2 2 0 0 2 2 2 0 Cell division protein CrgA DUF2970 PF11174.8 CDJ91685.1 - 2.6 7.9 7.9 0.66 9.9 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) PMM PF03332.13 CDJ91686.1 - 3.5e-100 334.3 0.6 4e-100 334.1 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 CDJ91686.1 - 4.8e-05 23.2 0.0 0.00022 21.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CDJ91686.1 - 0.0014 18.2 0.0 0.038 13.5 0.0 2.0 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase DUF5128 PF17170.4 CDJ91686.1 - 0.026 13.7 0.1 0.045 12.9 0.1 1.3 1 0 0 1 1 1 0 6-bladed beta-propeller Hydrolase PF00702.26 CDJ91686.1 - 0.095 13.0 0.0 0.15 12.3 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase GGDEF_2 PF17853.1 CDJ91686.1 - 0.15 12.3 0.0 7.7 6.8 0.0 2.4 2 0 0 2 2 2 0 GGDEF-like domain zf-CpG_bind_C PF12269.8 CDJ91687.1 - 5.3e-53 180.2 3.7 7.1e-53 179.8 3.7 1.2 1 0 0 1 1 1 1 CpG binding protein zinc finger C terminal domain zf-CXXC PF02008.20 CDJ91687.1 - 0.41 10.7 25.9 0.067 13.2 19.0 3.0 2 1 0 2 2 2 0 CXXC zinc finger domain SAP PF02037.27 CDJ91688.1 - 2.5e-10 39.9 1.1 2.5e-10 39.9 1.1 3.1 3 0 0 3 3 3 1 SAP domain EF-hand_7 PF13499.6 CDJ91688.1 - 0.0086 16.5 2.5 0.011 16.2 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair CBP_BcsG PF11658.8 CDJ91688.1 - 1.6 7.0 3.5 1 7.7 1.8 1.4 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsG Lectin_N PF03954.14 CDJ91688.1 - 1.6 8.5 7.7 4.1 7.2 2.1 3.0 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain HSP90 PF00183.18 CDJ91688.1 - 2.4 7.0 39.1 0.014 14.3 9.4 3.3 3 0 0 3 3 3 0 Hsp90 protein SpoIIP PF07454.11 CDJ91688.1 - 2.5 7.5 25.7 0.37 10.2 2.1 3.1 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) zinc_ribbon_16 PF17034.5 CDJ91690.1 - 5.1e-15 55.8 9.1 2.2e-14 53.7 9.1 2.0 1 1 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 CDJ91690.1 - 6.7e-06 25.6 5.9 2.3e-05 23.9 5.9 2.0 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Solute_trans_a PF03619.16 CDJ91691.1 - 6e-19 68.6 19.8 7.2e-19 68.3 19.8 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Collagen PF01391.18 CDJ91692.1 - 1.8e-24 85.2 76.4 2.6e-09 36.7 25.7 4.2 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Ig_3 PF13927.6 CDJ91693.1 - 3.8e-09 37.0 0.2 0.004 17.7 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 CDJ91693.1 - 1.1e-05 25.6 0.2 0.093 13.1 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 CDJ91693.1 - 1.1e-05 25.3 0.1 0.034 14.2 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 CDJ91693.1 - 0.002 18.3 0.1 3.1 8.1 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain TNFR_c6 PF00020.18 CDJ91694.1 - 1.3e-07 31.9 13.4 2.7e-07 30.9 13.4 1.6 1 0 0 1 1 1 1 TNFR/NGFR cysteine-rich region BCMA-Tall_bind PF09257.10 CDJ91694.1 - 0.0043 17.1 3.6 0.0093 16.0 3.6 1.6 1 0 0 1 1 1 1 BCMA, TALL-1 binding ASC PF00858.24 CDJ91695.1 - 6.7e-50 170.3 0.3 6.7e-50 170.3 0.3 4.0 2 1 1 3 3 3 1 Amiloride-sensitive sodium channel DAGK_acc PF00609.19 CDJ91695.1 - 4.5e-39 134.3 0.0 7.7e-39 133.6 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 CDJ91695.1 - 1.7e-20 72.9 0.0 2.8e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain EGF PF00008.27 CDJ91695.1 - 2.5e-18 66.0 132.0 1.7e-05 25.0 8.3 11.6 12 0 0 12 12 12 8 EGF-like domain C1_1 PF00130.22 CDJ91695.1 - 3.5e-09 36.4 20.0 1.6e-05 24.7 8.8 3.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) hEGF PF12661.7 CDJ91695.1 - 8.1e-07 29.4 107.7 0.044 14.4 2.8 12.1 11 0 0 11 11 11 8 Human growth factor-like EGF NAD_kinase PF01513.21 CDJ91695.1 - 0.19 10.9 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 ATP-NAD kinase Mob1_phocein PF03637.17 CDJ91696.1 - 4.8e-37 127.6 0.0 6e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family Asp PF00026.23 CDJ91697.1 - 1.3e-88 297.5 1.9 1.6e-88 297.2 1.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ91697.1 - 1.2e-10 41.9 10.3 1.3e-10 41.8 6.7 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ91697.1 - 1.4e-05 24.9 0.0 0.00016 21.5 0.0 2.6 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CDJ91697.1 - 0.00082 20.0 0.0 0.9 10.2 0.0 3.0 3 0 0 3 3 3 2 Aspartyl protease Peptidase_C1 PF00112.23 CDJ91698.1 - 3.7e-61 207.0 0.1 7.5e-61 206.0 0.1 1.5 1 0 0 1 1 1 1 Papain family cysteine protease VWC PF00093.18 CDJ91698.1 - 0.01 16.2 4.7 0.01 16.2 4.7 2.7 2 1 0 2 2 2 0 von Willebrand factor type C domain Somatomedin_B PF01033.17 CDJ91698.1 - 0.033 14.6 15.9 0.033 14.6 15.9 2.9 2 1 1 3 3 3 0 Somatomedin B domain Pkinase PF00069.25 CDJ91699.1 - 1.7e-22 80.0 0.0 6.4e-22 78.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ91699.1 - 2.7e-10 40.0 0.1 1e-09 38.1 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ91699.1 - 0.00021 20.2 0.0 0.00056 18.8 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDJ91699.1 - 0.00078 19.4 0.0 0.0017 18.3 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ91699.1 - 0.086 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 CDJ91700.1 - 2.3e-55 183.3 16.3 4.2e-09 36.9 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ91700.1 - 9e-24 83.6 0.1 0.00047 20.4 0.0 5.5 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDJ91700.1 - 2.7e-15 56.0 7.4 0.061 12.0 0.2 6.0 1 1 5 6 6 6 6 Nucleoporin Nup120/160 eIF2A PF08662.11 CDJ91700.1 - 3.6e-10 40.0 0.2 0.00011 22.2 0.0 3.8 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CDJ91700.1 - 2.3e-06 26.8 7.8 0.38 9.7 1.1 4.7 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CDJ91700.1 - 4.3e-05 23.0 0.0 0.025 13.9 0.0 3.0 1 1 3 4 4 4 3 WD40-like domain PALB2_WD40 PF16756.5 CDJ91700.1 - 7.4e-05 21.8 3.5 1.5 7.7 0.1 4.3 1 1 2 4 4 4 3 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 CDJ91700.1 - 0.021 13.1 0.0 0.054 11.8 0.0 1.6 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz VID27 PF08553.10 CDJ91700.1 - 0.072 12.1 0.0 0.33 10.0 0.0 1.9 1 1 1 2 2 2 0 VID27 C-terminal WD40-like domain RicinB_lectin_2 PF14200.6 CDJ91700.1 - 1 10.2 3.5 1.3 9.8 0.0 2.9 3 1 0 3 3 3 0 Ricin-type beta-trefoil lectin domain-like VWA PF00092.28 CDJ91702.1 - 2.1e-06 28.1 0.3 0.0049 17.1 0.0 2.5 2 1 0 2 2 2 2 von Willebrand factor type A domain SPX PF03105.19 CDJ91702.1 - 0.26 11.1 5.7 0.36 10.7 5.7 1.3 1 0 0 1 1 1 0 SPX domain Vps53_N PF04100.12 CDJ91703.1 - 2.7e-143 477.5 8.5 1.9e-125 418.8 4.2 2.2 2 0 0 2 2 2 2 Vps53-like, N-terminal HTH_48 PF17906.1 CDJ91703.1 - 1.3e-22 79.7 0.2 2e-11 43.8 0.1 2.7 2 0 0 2 2 2 2 HTH domain in Mos1 transposase VPS53_C PF16854.5 CDJ91703.1 - 0.00019 21.4 0.0 0.00071 19.5 0.0 1.9 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 53 C-terminus DUF2451 PF10474.9 CDJ91703.1 - 0.0059 16.4 0.1 0.019 14.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Spc7 PF08317.11 CDJ91703.1 - 0.0099 14.8 2.9 0.026 13.4 2.9 1.6 1 0 0 1 1 1 1 Spc7 kinetochore protein PX PF00787.24 CDJ91703.1 - 0.04 13.9 0.3 15 5.6 0.0 2.6 2 0 0 2 2 2 0 PX domain Filament PF00038.21 CDJ91703.1 - 0.044 13.4 4.1 0.11 12.1 4.1 1.6 1 0 0 1 1 1 0 Intermediate filament protein DUF2730 PF10805.8 CDJ91703.1 - 0.26 11.4 5.1 0.74 9.9 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2730) Baculo_PEP_C PF04513.12 CDJ91703.1 - 0.39 10.8 15.6 0.21 11.6 3.8 3.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vps54_N PF10475.9 CDJ91703.1 - 0.56 9.4 2.6 1.2 8.4 2.6 1.5 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex TMF_TATA_bd PF12325.8 CDJ91703.1 - 2.2 8.5 7.3 1.4 9.1 3.7 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ABC_tran_CTD PF16326.5 CDJ91703.1 - 2.5 8.4 13.1 0.67 10.2 2.8 3.4 3 1 1 4 4 3 0 ABC transporter C-terminal domain Striatin PF08232.12 CDJ91703.1 - 5.6 7.6 7.6 2.1 9.0 0.3 2.6 2 0 0 2 2 2 0 Striatin family Kin17_mid PF10357.9 CDJ91704.1 - 1.9e-47 160.3 3.8 1.9e-47 160.3 3.8 2.8 2 1 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 CDJ91704.1 - 5.4e-20 71.2 3.6 5.4e-20 71.2 3.6 2.0 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain zf-met PF12874.7 CDJ91704.1 - 0.013 15.9 6.5 0.025 15.0 6.5 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDJ91704.1 - 0.015 15.5 6.0 0.045 14.0 6.0 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding TFIID_NTD2 PF04494.15 CDJ91704.1 - 0.033 14.4 0.1 0.075 13.3 0.1 1.6 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain zf-C2H2_2 PF12756.7 CDJ91704.1 - 0.17 12.3 8.0 0.37 11.2 3.9 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) CarbpepA_inh PF02977.15 CDJ91704.1 - 0.58 10.0 3.5 3.6 7.4 3.1 2.3 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor Phage_GP20 PF06810.11 CDJ91704.1 - 9.3 6.0 14.2 0.085 12.7 2.6 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF1754 PF08555.10 CDJ91705.1 - 0.0052 17.6 18.6 0.36 11.6 10.6 2.7 1 1 1 2 2 2 2 Eukaryotic family of unknown function (DUF1754) Aa_trans PF01490.18 CDJ91706.1 - 8.7e-90 301.4 23.3 1e-89 301.1 23.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ceramidase PF05875.12 CDJ91706.1 - 1.9 7.9 11.7 0.21 11.0 0.4 2.7 3 0 0 3 3 3 0 Ceramidase 7tm_1 PF00001.21 CDJ91707.1 - 1.6e-11 44.0 24.8 2.2e-11 43.6 24.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) HMG_box PF00505.19 CDJ91708.1 - 2.3e-09 37.5 0.2 3.7e-09 36.9 0.2 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ91708.1 - 3.7e-05 24.2 0.1 6.3e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 HMG-box domain Myotub-related PF06602.14 CDJ91709.1 - 2.8e-108 362.0 0.2 4.3e-108 361.4 0.2 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FYVE PF01363.21 CDJ91709.1 - 1.1e-08 35.1 9.1 1.1e-08 35.1 9.1 2.4 2 0 0 2 2 2 1 FYVE zinc finger Y_phosphatase3 PF13350.6 CDJ91709.1 - 0.0099 15.9 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CDJ91709.1 - 0.14 11.7 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ91709.1 - 0.16 11.8 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF4083 PF13314.6 CDJ91710.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) ABC_tran_2 PF16949.5 CDJ91711.1 - 0.034 13.0 0.1 0.041 12.7 0.1 1.0 1 0 0 1 1 1 0 Putative ATP-binding cassette DUF4179 PF13786.6 CDJ91711.1 - 0.093 13.2 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) VirB8 PF04335.13 CDJ91711.1 - 0.11 12.4 0.1 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 VirB8 protein DUF872 PF05915.12 CDJ91711.1 - 0.12 12.5 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) FoP_duplication PF13865.6 CDJ91712.1 - 6.8e-09 36.2 13.2 5.6e-08 33.2 4.7 2.4 2 0 0 2 2 2 2 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.22 CDJ91712.1 - 0.098 12.5 0.1 0.49 10.3 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DHHC PF01529.20 CDJ91713.1 - 2.6e-33 115.0 5.4 2.6e-33 115.0 5.4 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Oxidored_q5_N PF01059.17 CDJ91713.1 - 0.012 15.7 0.0 0.012 15.7 0.0 2.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus SH3_9 PF14604.6 CDJ91713.1 - 0.041 13.7 0.2 0.099 12.5 0.2 1.6 1 0 0 1 1 1 0 Variant SH3 domain SH3_2 PF07653.17 CDJ91713.1 - 0.046 13.4 0.2 0.14 11.8 0.2 1.8 1 0 0 1 1 1 0 Variant SH3 domain MSSP PF03940.13 CDJ91713.1 - 0.11 12.2 2.8 0.19 11.3 2.8 1.4 1 0 0 1 1 1 0 Male specific sperm protein TatC PF00902.18 CDJ91713.1 - 2.6 7.8 10.5 44 3.8 10.5 2.1 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) CC PF04942.14 CDJ91714.1 - 0.0035 17.5 13.7 0.0068 16.6 13.7 1.4 1 0 0 1 1 1 1 CC domain STN1_2 PF09170.10 CDJ91716.1 - 0.0016 18.7 0.1 0.0022 18.3 0.1 1.2 1 0 0 1 1 1 1 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Orbi_VP6 PF01516.16 CDJ91716.1 - 0.0052 16.4 0.3 0.0061 16.1 0.3 1.1 1 0 0 1 1 1 1 Orbivirus helicase VP6 Peptidase_M13_N PF05649.13 CDJ91717.1 - 3e-56 191.8 0.5 3.6e-56 191.5 0.5 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 CDJ91718.1 - 1.3e-68 230.7 0.0 1.8e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Biotin_carb_C PF02785.19 CDJ91719.1 - 3.1e-30 104.4 0.0 2.4e-29 101.6 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain CPSase_L_D2 PF02786.17 CDJ91719.1 - 8.7e-25 87.5 0.0 1.7e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_lipoyl PF00364.22 CDJ91719.1 - 6.9e-14 51.4 2.2 1.2e-13 50.7 0.7 2.3 3 0 0 3 3 3 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CDJ91719.1 - 8.8e-06 25.5 5.0 0.00019 21.2 0.2 3.4 3 1 1 4 4 4 1 Biotin-lipoyl like HlyD_3 PF13437.6 CDJ91719.1 - 0.0045 17.7 0.1 7.7 7.3 0.0 3.3 3 1 0 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 CDJ91719.1 - 0.011 14.9 0.0 0.25 10.5 0.0 2.2 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion ArsA_HSP20 PF17886.1 CDJ91719.1 - 0.015 14.9 0.0 0.038 13.6 0.0 1.7 1 0 0 1 1 1 0 HSP20-like domain found in ArsA Dala_Dala_lig_C PF07478.13 CDJ91719.1 - 0.017 14.6 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus NQRA PF05896.11 CDJ91719.1 - 0.021 14.3 0.1 0.034 13.6 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DUF2118 PF09891.9 CDJ91719.1 - 0.12 12.3 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) LAL_C2 PF18603.1 CDJ91719.1 - 0.38 10.9 2.1 3.2 8.0 0.3 3.3 3 1 0 3 3 3 0 L-amino acid ligase C-terminal domain 2 SPARC_Ca_bdg PF10591.9 CDJ91720.1 - 8.1e-36 122.8 2.3 8.1e-36 122.8 2.3 2.0 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_2 PF07648.15 CDJ91720.1 - 3.1e-12 46.4 11.3 3.1e-12 46.4 11.3 2.3 3 1 0 3 3 3 1 Kazal-type serine protease inhibitor domain FOLN PF09289.10 CDJ91720.1 - 4.8e-06 26.6 9.5 4.8e-06 26.6 9.5 2.9 3 0 0 3 3 2 1 Follistatin/Osteonectin-like EGF domain EF-hand_5 PF13202.6 CDJ91720.1 - 0.0017 17.8 0.6 0.012 15.1 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 CDJ91720.1 - 0.0048 16.3 2.3 0.012 15.1 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CDJ91720.1 - 0.0068 16.2 1.7 0.035 14.0 0.1 2.9 3 0 0 3 3 3 1 EF-hand domain SH2_2 PF14633.6 CDJ91720.1 - 0.032 13.7 0.3 0.061 12.7 0.3 1.5 1 0 0 1 1 1 0 SH2 domain Pdase_C33_assoc PF14756.6 CDJ91720.1 - 0.071 13.0 1.5 0.14 12.1 1.5 1.4 1 0 0 1 1 1 0 Peptidase_C33-associated domain EF-hand_7 PF13499.6 CDJ91720.1 - 0.096 13.1 1.6 19 5.8 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain pair UDPG_MGDP_dh_N PF03721.14 CDJ91720.1 - 0.17 11.4 0.1 0.29 10.7 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sds3 PF08598.11 CDJ91720.1 - 0.95 9.4 7.3 0.42 10.6 2.9 1.9 2 0 0 2 2 2 0 Sds3-like Kazal_1 PF00050.21 CDJ91720.1 - 2.6 8.1 19.3 0.14 12.1 10.9 3.2 3 1 0 3 3 3 0 Kazal-type serine protease inhibitor domain ISP1_C PF18161.1 CDJ91721.1 - 0.14 12.1 0.1 0.68 10.0 0.1 1.9 2 0 0 2 2 2 0 ISP1 C-terminal REV1_C PF16727.5 CDJ91722.1 - 0.078 13.4 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain F-box_5 PF18511.1 CDJ91722.1 - 0.14 11.7 0.0 0.39 10.3 0.0 1.7 2 0 0 2 2 2 0 F-box zf-C4 PF00105.18 CDJ91723.1 - 4.8e-27 94.2 16.2 7.9e-27 93.5 16.2 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ91723.1 - 1.2e-07 31.6 0.1 4.1e-07 29.8 0.1 1.8 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor PH_3 PF14593.6 CDJ91723.1 - 0.048 13.8 0.0 3.2 7.9 0.0 2.9 2 1 0 2 2 2 0 PH domain Aldedh PF00171.22 CDJ91724.1 - 8.5e-81 271.8 0.1 1e-80 271.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 CDJ91725.1 - 9.3e-135 449.7 0.1 1.2e-134 449.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRF PF01765.19 CDJ91725.1 - 0.088 12.8 1.5 0.16 11.9 1.5 1.3 1 0 0 1 1 1 0 Ribosome recycling factor LuxC PF05893.14 CDJ91725.1 - 0.12 11.4 0.0 0.92 8.5 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Aldedh PF00171.22 CDJ91726.1 - 6.8e-133 443.5 0.2 8e-133 443.3 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Macoilin PF09726.9 CDJ91727.1 - 1.3 7.4 6.6 1.7 7.1 6.6 1.0 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 CDJ91727.1 - 8.7 4.9 7.6 11 4.5 7.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SH2 PF00017.24 CDJ91729.1 - 9e-27 93.0 0.7 5.6e-18 64.8 0.0 3.3 3 0 0 3 3 3 3 SH2 domain SH2_2 PF14633.6 CDJ91729.1 - 0.00015 21.3 3.2 0.00021 20.8 0.1 2.8 3 1 1 4 4 4 1 SH2 domain Cyclin_N PF00134.23 CDJ91730.1 - 2.7e-28 98.3 0.3 4.1e-28 97.7 0.3 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain HA70_C PF17993.1 CDJ91730.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Haemagglutinin 70 C-terminal domain Il13Ra_Ig PF18001.1 CDJ91731.1 - 0.048 13.8 0.3 0.096 12.8 0.3 1.5 1 0 0 1 1 1 0 Interleukin-13 receptor subunit alpha Ig-like domain Imm57 PF15596.6 CDJ91731.1 - 0.13 12.6 0.2 0.22 11.9 0.2 1.5 1 0 0 1 1 1 0 Immunity protein 57 Tetraspanin PF00335.20 CDJ91732.1 - 0.0041 16.9 11.1 0.016 14.9 11.1 2.1 1 1 0 1 1 1 1 Tetraspanin family LHC PF00556.20 CDJ91732.1 - 0.14 12.4 1.2 0.81 9.9 0.0 2.4 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit TED_complement PF07678.14 CDJ91733.1 - 1.7e-89 299.9 0.1 1.2e-88 297.1 0.0 2.3 3 0 0 3 3 3 1 A-macroglobulin TED domain A2M PF00207.22 CDJ91733.1 - 2.3e-24 85.1 0.0 6.6e-24 83.6 0.0 1.9 1 0 0 1 1 1 1 Alpha-2-macroglobulin family zinc-ribbons_6 PF07191.12 CDJ91734.1 - 0.046 13.7 0.2 2.1 8.4 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbons zinc_ribbon_2 PF13240.6 CDJ91734.1 - 0.052 13.3 0.3 0.17 11.7 0.3 1.9 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 CDJ91734.1 - 0.11 11.9 0.5 0.59 9.6 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 CDJ91734.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 Double zinc ribbon Nudix_N_2 PF14803.6 CDJ91734.1 - 0.17 11.8 1.1 0.39 10.7 0.1 2.1 2 0 0 2 2 2 0 Nudix N-terminal CUT PF02376.15 CDJ91736.1 - 1.2e-67 224.0 0.2 5.2e-23 81.0 0.1 3.6 3 0 0 3 3 3 3 CUT domain CASP_C PF08172.12 CDJ91736.1 - 3.8e-41 141.1 6.7 3.8e-41 141.1 6.7 4.9 2 2 1 3 3 3 1 CASP C terminal Homeodomain PF00046.29 CDJ91736.1 - 2.2e-13 49.8 3.8 8.9e-13 47.9 3.8 2.2 1 0 0 1 1 1 1 Homeodomain HNF-1_N PF04814.13 CDJ91736.1 - 1e-05 26.3 1.9 0.0028 18.3 0.9 3.9 3 0 0 3 3 3 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus HTH_34 PF13601.6 CDJ91736.1 - 0.0018 18.4 0.0 1 9.6 0.0 3.9 3 0 0 3 3 3 1 Winged helix DNA-binding domain Homeobox_KN PF05920.11 CDJ91736.1 - 0.011 15.6 0.1 0.035 14.0 0.1 1.9 1 0 0 1 1 1 0 Homeobox KN domain HTH_ABP1_N PF18107.1 CDJ91736.1 - 0.17 11.6 5.6 0.075 12.8 0.3 3.3 4 0 0 4 4 4 0 Fission yeast centromere protein N-terminal domain Nodulin_late PF07127.11 CDJ91736.1 - 0.27 11.6 0.3 0.47 10.8 0.3 1.3 1 0 0 1 1 1 0 Late nodulin protein Zona_pellucida PF00100.23 CDJ91737.1 - 1.7e-09 37.8 0.1 3.7e-09 36.8 0.0 1.6 2 0 0 2 2 2 1 Zona pellucida-like domain Herpes_UL42 PF02282.16 CDJ91737.1 - 0.026 14.4 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase processivity factor (UL42) VWA PF00092.28 CDJ91738.1 - 5.4e-13 49.6 0.1 7e-13 49.2 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CDJ91738.1 - 3.2e-09 37.4 0.1 4.2e-09 37.0 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain BAR PF03114.18 CDJ91742.1 - 1.3e-13 51.2 8.4 1.6e-13 50.9 8.4 1.1 1 0 0 1 1 1 1 BAR domain Cep57_CLD_2 PF14197.6 CDJ91742.1 - 0.14 12.2 1.6 1.6 8.8 0.0 2.6 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 S4 PF01479.25 CDJ91743.1 - 1.1e-09 37.9 0.2 1.9e-09 37.1 0.2 1.4 1 0 0 1 1 1 1 S4 domain HTH_34 PF13601.6 CDJ91743.1 - 0.16 12.2 0.1 11 6.3 0.0 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain Epimerase PF01370.21 CDJ91744.1 - 1.4e-51 175.3 0.0 2e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CDJ91744.1 - 1.9e-48 165.6 0.0 2.8e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CDJ91744.1 - 9.6e-14 51.0 0.0 1.6e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GTP_EFTU PF00009.27 CDJ91744.1 - 2.2e-12 47.0 0.1 3.4e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Polysacc_synt_2 PF02719.15 CDJ91744.1 - 2.2e-12 46.7 0.0 3e-11 43.0 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CDJ91744.1 - 1.4e-10 40.8 0.0 2.6e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain GTP_EFTU_D2 PF03144.25 CDJ91744.1 - 8e-08 32.6 0.7 2.4e-06 27.8 0.2 3.1 3 0 0 3 3 3 1 Elongation factor Tu domain 2 NAD_binding_4 PF07993.12 CDJ91744.1 - 2.8e-07 30.0 0.0 3.2e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein KR PF08659.10 CDJ91744.1 - 1.1e-05 25.4 0.0 2.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CDJ91744.1 - 0.0034 17.3 0.0 0.062 13.2 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 CDJ91744.1 - 0.0069 15.9 0.1 0.02 14.4 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase RsgA_GTPase PF03193.16 CDJ91744.1 - 0.0083 16.0 0.3 0.021 14.8 0.2 1.7 2 0 0 2 2 2 1 RsgA GTPase adh_short_C2 PF13561.6 CDJ91744.1 - 0.087 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 CDJ91744.1 - 0.11 12.0 0.4 5.1 6.6 0.2 3.0 2 1 0 2 2 2 0 NmrA-like family BAR PF03114.18 CDJ91745.1 - 3.6e-10 39.9 13.4 1.3e-08 34.8 9.4 2.0 1 1 1 2 2 2 2 BAR domain Glutaredoxin2_C PF04399.13 CDJ91745.1 - 0.2 11.5 6.4 6.2 6.7 0.1 3.3 1 1 2 3 3 3 0 Glutaredoxin 2, C terminal domain MerR-DNA-bind PF09278.11 CDJ91745.1 - 0.34 11.5 3.0 39 4.9 0.1 3.2 3 0 0 3 3 3 0 MerR, DNA binding Nup54 PF13874.6 CDJ91745.1 - 0.98 9.5 11.4 0.14 12.2 2.9 2.8 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 DUF1284 PF06935.11 CDJ91745.1 - 1.2 9.7 6.5 3.7 8.1 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1284) XhlA PF10779.9 CDJ91745.1 - 2.7 8.2 15.9 0.74 10.1 0.3 3.3 3 1 1 4 4 4 0 Haemolysin XhlA PIN_2 PF10130.9 CDJ91745.1 - 2.8 8.2 6.8 3.5 7.9 1.9 2.6 1 1 1 3 3 3 0 PIN domain Snapin_Pallidin PF14712.6 CDJ91745.1 - 5.5 7.5 13.9 0.99 9.9 3.1 3.4 2 2 1 3 3 3 0 Snapin/Pallidin DUF2797 PF10977.8 CDJ91745.1 - 7.2 6.4 11.6 0.51 10.2 1.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2797) CorA PF01544.18 CDJ91745.1 - 7.3 5.8 7.1 4.3 6.6 0.6 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein PEX11 PF05648.14 CDJ91746.1 - 1e-21 77.4 5.5 9.3e-21 74.3 0.7 2.0 1 1 1 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) eIF-6 PF01912.18 CDJ91747.1 - 4.1e-72 241.7 0.3 5.5e-72 241.3 0.3 1.2 1 0 0 1 1 1 1 eIF-6 family TRAUB PF08164.12 CDJ91748.1 - 2.4e-23 82.5 1.2 2.4e-23 82.5 1.2 2.6 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 CDJ91748.1 - 1.3e-21 77.7 3.3 1.3e-21 77.7 3.3 2.7 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor BC10 PF06726.12 CDJ91749.1 - 3.9e-13 49.4 6.6 4.9e-13 49.1 6.6 1.1 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 DUF4131 PF13567.6 CDJ91749.1 - 3.5 7.2 4.7 4.2 7.0 4.3 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) RVT_1 PF00078.27 CDJ91750.1 - 6e-34 117.5 0.0 9.9e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.22 CDJ91752.1 - 1.1e-09 37.9 0.0 2.7e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CDJ91752.1 - 0.0064 16.5 2.8 0.0065 16.5 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif Lge1 PF11488.8 CDJ91752.1 - 0.031 14.5 0.2 0.095 12.9 0.2 1.9 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 NCBP3 PF10309.9 CDJ91752.1 - 0.074 12.9 0.0 0.81 9.6 0.0 2.4 1 1 0 1 1 1 0 Nuclear cap-binding protein subunit 3 Nup35_RRM_2 PF14605.6 CDJ91752.1 - 0.086 12.9 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif BRAP2 PF07576.12 CDJ91752.1 - 0.17 12.1 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 BRCA1-associated protein 2 DUF5045 PF16464.5 CDJ91753.1 - 0.044 14.1 0.1 0.083 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5045) HSP20 PF00011.21 CDJ91754.1 - 4.5e-20 71.7 0.0 6e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ91754.1 - 0.017 14.7 0.1 0.037 13.6 0.1 1.6 1 1 0 1 1 1 0 HSP20-like domain found in ArsA Actin PF00022.19 CDJ91755.1 - 1.8e-41 142.2 0.0 2.4e-39 135.1 0.0 2.9 1 1 0 1 1 1 1 Actin UNC-93 PF05978.16 CDJ91756.1 - 4.4e-38 130.5 9.8 5.2e-38 130.2 9.8 1.0 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 3HCDH_RFF PF18321.1 CDJ91757.1 - 0.016 15.6 0.4 0.09 13.2 0.4 1.9 1 1 1 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain CCDC-167 PF15188.6 CDJ91757.1 - 0.032 14.6 0.2 0.054 13.8 0.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF1679 PF07914.11 CDJ91758.1 - 5.2e-40 137.6 0.0 5.8e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 CDJ91758.1 - 1.9e-15 57.0 0.0 2.6e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 CDJ91758.1 - 1.6e-05 25.0 0.0 1.9e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDJ91758.1 - 0.066 12.8 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 CDJ91759.1 - 1.3e-23 83.5 3.2 1.9e-18 66.5 0.6 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1679) DUF3379 PF11859.8 CDJ91760.1 - 0.098 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) BRCT PF00533.26 CDJ91761.1 - 4.6e-06 26.9 0.0 0.019 15.3 0.0 2.5 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CDJ91761.1 - 0.0016 18.3 0.0 2.7 8.0 0.0 2.5 2 0 0 2 2 2 2 twin BRCT domain Glyco_tran_WecB PF03808.13 CDJ91761.1 - 0.048 13.6 0.0 2 8.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Ras PF00071.22 CDJ91762.1 - 2.4e-10 40.2 0.0 3e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Ras family DUF2677 PF10838.8 CDJ91762.1 - 0.12 12.3 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2677) 7tm_1 PF00001.21 CDJ91764.1 - 0.0074 15.6 2.3 0.0074 15.6 2.3 3.0 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) MASE2 PF05230.11 CDJ91764.1 - 0.018 15.1 3.1 0.018 15.1 3.1 2.7 3 1 1 4 4 4 0 MASE2 domain DUF3810 PF12725.7 CDJ91764.1 - 1.1 8.6 7.1 0.49 9.7 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DEAD_2 PF06733.15 CDJ91766.1 - 1.3e-51 174.7 4.8 2.1e-51 174.1 4.8 1.3 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 CDJ91766.1 - 2.7e-49 167.6 0.0 6.5e-49 166.4 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 CDJ91766.1 - 0.00054 20.0 0.0 0.47 10.4 0.0 3.1 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ91766.1 - 0.0032 17.3 0.1 0.093 12.5 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase HBB PF06777.11 CDJ91766.1 - 0.1 12.3 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Helical and beta-bridge domain ARID PF01388.21 CDJ91767.1 - 1.4e-15 57.8 0.0 2.9e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Methyltransf_32 PF13679.6 CDJ91768.1 - 4.4e-20 72.3 0.0 9.6e-20 71.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.14 CDJ91768.1 - 0.001 18.7 0.0 0.7 9.4 0.0 2.6 2 1 0 2 2 2 2 Methyltransferase TRM13 RrnaAD PF00398.20 CDJ91768.1 - 0.0018 17.4 0.0 0.0029 16.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.6 CDJ91768.1 - 0.0092 15.8 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CDJ91768.1 - 0.021 14.3 0.0 0.048 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 CDJ91768.1 - 0.049 13.2 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 CDJ91768.1 - 0.094 12.5 0.0 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) COesterase PF00135.28 CDJ91769.1 - 2.4e-136 455.6 0.0 3.1e-136 455.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Ribosomal_L23eN PF03939.13 CDJ91769.1 - 2.3e-18 66.1 13.9 4.3e-18 65.3 13.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 CDJ91769.1 - 4.1e-15 55.9 1.6 4.1e-15 55.9 1.6 2.0 2 0 0 2 2 2 1 Ribosomal protein L23 Abhydrolase_3 PF07859.13 CDJ91769.1 - 4.9e-06 26.6 0.8 1.7e-05 24.8 0.8 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CDJ91769.1 - 0.0017 17.9 0.4 0.0032 17.0 0.4 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 CDJ91769.1 - 0.076 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 CDJ91769.1 - 0.7 10.5 9.2 0.041 14.5 3.0 2.1 2 1 0 2 2 2 0 Alpha/beta hydrolase family RGS PF00615.19 CDJ91770.1 - 4.5e-35 120.5 2.2 6.6e-35 119.9 2.2 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain APC_u15 PF16636.5 CDJ91770.1 - 0.064 13.7 2.9 0.44 11.0 0.4 2.4 2 0 0 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 PPP4R2 PF09184.11 CDJ91771.1 - 3.4e-25 89.2 1.2 8.8e-25 87.9 0.0 1.9 2 0 0 2 2 2 1 PPP4R2 Peptidase_M16 PF00675.20 CDJ91771.1 - 1.2e-15 57.8 0.0 2.5e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CDJ91771.1 - 0.00034 20.7 0.0 0.0018 18.3 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain DUF2358 PF10184.9 CDJ91772.1 - 4.4e-13 49.5 0.2 5.9e-13 49.1 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) PDZ PF00595.24 CDJ91774.1 - 8.2e-09 35.7 1.5 4e-08 33.5 0.0 2.6 3 0 0 3 3 3 1 PDZ domain PDZ_6 PF17820.1 CDJ91774.1 - 8.9e-09 35.1 0.1 1.9e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 PDZ domain EBP50_C PF09007.11 CDJ91774.1 - 0.023 15.7 4.9 0.023 15.7 4.9 2.2 1 1 1 2 2 2 0 EBP50, C-terminal DUF3301 PF11743.8 CDJ91775.1 - 0.04 13.6 0.5 11 5.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) PABP PF00658.18 CDJ91775.1 - 0.094 12.9 0.1 23 5.2 0.0 2.4 2 0 0 2 2 2 0 Poly-adenylate binding protein, unique domain Mononeg_mRNAcap PF14318.6 CDJ91775.1 - 0.12 11.6 1.8 9.1 5.4 0.1 2.1 2 0 0 2 2 2 0 Mononegavirales mRNA-capping region V DinB_2 PF12867.7 CDJ91775.1 - 0.27 11.8 8.6 3 8.3 0.2 2.9 3 0 0 3 3 3 0 DinB superfamily PmrD PF11183.8 CDJ91775.1 - 4.4 7.5 6.5 64 3.8 0.4 4.2 4 2 0 4 4 4 0 Polymyxin resistance protein PmrD Laminin_EGF PF00053.24 CDJ91776.1 - 1.8e-77 255.3 196.1 5.3e-11 42.5 13.7 10.5 10 0 0 10 10 10 10 Laminin EGF domain Laminin_B PF00052.18 CDJ91776.1 - 7.2e-26 90.7 0.0 9.6e-26 90.3 0.0 1.2 1 0 0 1 1 1 1 Laminin B (Domain IV) SCVP PF17619.2 CDJ91777.1 - 3.4e-26 91.9 0.2 5.3e-26 91.3 0.2 1.3 1 0 0 1 1 1 1 Secreted clade V proteins DUF3439 PF11921.8 CDJ91777.1 - 0.0075 16.2 4.3 0.0075 16.2 4.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) DUF1759 PF03564.15 CDJ91778.1 - 3e-10 40.2 1.4 1.4e-09 38.1 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) Transposase_1 PF01359.18 CDJ91780.1 - 8.1e-26 89.7 0.0 1.6e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 CDJ91780.1 - 3.2e-07 30.2 0.0 5.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Sigma70_r4 PF04545.16 CDJ91780.1 - 0.084 12.4 0.1 0.21 11.1 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 Asp_protease_2 PF13650.6 CDJ91782.1 - 1.1e-09 38.7 0.0 2.3e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ91782.1 - 2.1e-09 37.8 0.0 4.7e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ91782.1 - 0.00019 21.7 0.0 0.00033 20.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease eIF3g PF12353.8 CDJ91782.1 - 0.0033 17.8 0.7 0.0033 17.8 0.7 1.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G Asp_protease PF09668.10 CDJ91782.1 - 0.091 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease zf-C2H2 PF00096.26 CDJ91784.1 - 5.4e-19 67.5 26.5 8.3e-05 22.8 2.5 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ91784.1 - 4.9e-12 45.6 25.4 0.0034 18.1 2.1 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDJ91784.1 - 8.2e-09 35.5 22.9 0.00084 19.7 0.5 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CDJ91784.1 - 3.9e-06 27.0 10.7 0.061 13.6 0.0 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CDJ91784.1 - 6.2e-06 26.4 14.0 0.0045 17.3 1.8 3.3 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 CDJ91784.1 - 0.0012 19.5 11.5 0.39 11.4 0.4 3.7 2 1 0 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 CDJ91784.1 - 0.0025 18.1 13.6 0.55 10.6 0.2 4.1 2 1 2 4 4 4 2 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 CDJ91784.1 - 0.0047 16.5 9.7 3.2 7.4 0.0 4.4 4 0 0 4 4 4 2 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 CDJ91784.1 - 0.0053 16.9 6.7 1.7 8.9 0.3 3.7 3 1 0 3 3 3 1 Zinc ribbon domain DZR PF12773.7 CDJ91784.1 - 0.014 15.4 9.6 0.19 11.8 3.2 3.0 2 1 1 3 3 3 0 Double zinc ribbon BolA PF01722.18 CDJ91784.1 - 0.079 13.3 2.2 0.091 13.1 0.2 2.2 2 1 1 3 3 2 0 BolA-like protein zf-trcl PF13451.6 CDJ91784.1 - 0.083 12.8 9.7 1.7 8.6 0.1 4.2 4 0 0 4 4 4 0 Probable zinc-ribbon domain LIM PF00412.22 CDJ91784.1 - 0.086 13.1 7.9 0.43 10.8 3.2 2.6 2 1 0 2 2 2 0 LIM domain Actin_micro PF17003.5 CDJ91784.1 - 0.14 11.3 12.7 7.7 5.6 0.2 3.0 2 1 0 2 2 2 0 Putative actin-like family Vps39_2 PF10367.9 CDJ91784.1 - 0.57 10.6 7.5 10 6.6 0.0 4.0 2 1 2 4 4 4 0 Vacuolar sorting protein 39 domain 2 zf_C2H2_ZHX PF18387.1 CDJ91784.1 - 0.66 9.7 7.8 3.4 7.4 0.0 3.7 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain HNH PF01844.23 CDJ91784.1 - 0.69 10.1 16.1 0.83 9.9 0.5 3.8 4 0 0 4 4 4 0 HNH endonuclease CpXC PF14353.6 CDJ91784.1 - 0.74 9.9 11.0 9.2 6.3 0.3 4.0 2 1 0 2 2 2 0 CpXC protein C1_1 PF00130.22 CDJ91784.1 - 0.77 9.7 13.5 5.1 7.1 1.1 4.0 3 2 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-met PF12874.7 CDJ91784.1 - 0.79 10.2 0.1 0.79 10.2 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Rpr2 PF04032.16 CDJ91784.1 - 0.9 9.9 8.5 18 5.7 3.1 3.1 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Ribosomal_L28 PF00830.19 CDJ91784.1 - 1.1 9.5 3.7 12 6.2 0.0 2.6 2 0 0 2 2 2 0 Ribosomal L28 family zf-MYST PF17772.1 CDJ91784.1 - 1.7 8.3 7.5 8.6 6.0 0.1 3.8 4 1 0 4 4 4 0 MYST family zinc finger domain zf-BED PF02892.15 CDJ91784.1 - 3.2 7.9 20.3 5.6 7.1 5.5 3.5 2 1 1 3 3 3 0 BED zinc finger zinc_ribbon_5 PF13719.6 CDJ91784.1 - 4.9 7.0 7.0 19 5.1 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 CDJ91784.1 - 5 7.9 9.0 41 5.0 0.9 3.3 2 1 0 3 3 3 0 zinc-ribbon family DUF2256 PF10013.9 CDJ91784.1 - 5.7 7.1 8.2 15 5.8 0.0 3.9 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) PA PF02225.22 CDJ91785.1 - 6.4e-13 48.5 0.0 1.1e-12 47.8 0.0 1.4 1 1 0 1 1 1 1 PA domain C2 PF00168.30 CDJ91786.1 - 4e-26 91.3 0.1 6e-16 58.6 0.0 3.0 3 0 0 3 3 3 2 C2 domain PDZ_6 PF17820.1 CDJ91786.1 - 2.2e-11 43.4 0.0 5.7e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 PDZ domain FYVE_2 PF02318.16 CDJ91786.1 - 7e-11 42.4 10.0 1.3e-10 41.5 10.0 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger PDZ PF00595.24 CDJ91786.1 - 5.1e-10 39.6 0.1 1.5e-09 38.1 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ91786.1 - 0.0034 17.7 0.1 0.009 16.3 0.1 1.7 1 0 0 1 1 1 1 PDZ domain Pico_P1A PF02226.16 CDJ91786.1 - 0.05 13.7 0.1 0.16 12.0 0.1 1.8 1 0 0 1 1 1 0 Picornavirus coat protein (VP4) zf-piccolo PF05715.13 CDJ91786.1 - 0.6 10.3 8.9 1.3 9.2 8.9 1.6 1 0 0 1 1 1 0 Piccolo Zn-finger DHR-2 PF06920.13 CDJ91787.1 - 2.7e-117 392.6 0.0 4.7e-117 391.8 0.0 1.3 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 CDJ91787.1 - 2.4e-36 125.4 0.0 5.6e-36 124.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 CDJ91787.1 - 7.4e-21 74.7 0.5 2.2e-20 73.1 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3398) PH PF00169.29 CDJ91787.1 - 0.011 16.2 0.0 0.027 15.0 0.0 1.7 1 0 0 1 1 1 0 PH domain ArfGap PF01412.18 CDJ91788.1 - 2e-23 82.7 0.0 3.5e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Fis1_TPR_C PF14853.6 CDJ91789.1 - 5.6e-21 74.4 3.1 1.9e-20 72.7 1.4 2.1 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 CDJ91789.1 - 8.2e-06 25.4 0.0 1.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_16 PF13432.6 CDJ91789.1 - 0.0031 18.1 2.0 0.038 14.6 1.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ91789.1 - 0.11 13.4 3.0 0.96 10.4 0.9 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3349 PF11829.8 CDJ91789.1 - 0.12 13.1 0.2 0.24 12.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) Methyltransf_34 PF11312.8 CDJ91789.1 - 0.15 11.3 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase TPR_2 PF07719.17 CDJ91789.1 - 1.1 9.5 5.3 0.71 10.1 0.8 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Syndecan PF01034.20 CDJ91790.1 - 0.18 11.8 0.3 0.36 10.8 0.3 1.4 1 0 0 1 1 1 0 Syndecan domain RNase_PH PF01138.21 CDJ91791.1 - 2.2e-31 109.1 0.0 4.8e-21 75.7 0.0 2.4 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CDJ91791.1 - 1e-17 63.9 0.2 6e-11 42.2 0.1 2.5 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 PNPase PF03726.14 CDJ91791.1 - 3.2e-11 43.5 0.0 6.7e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain S1 PF00575.23 CDJ91791.1 - 2.2e-05 24.7 0.0 7.6e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 S1 RNA binding domain TRAM_LAG1_CLN8 PF03798.16 CDJ91792.1 - 9.5e-38 129.9 28.4 9.5e-38 129.9 28.4 1.4 2 0 0 2 2 2 1 TLC domain IRK_C PF17655.1 CDJ91794.1 - 6.2e-45 152.9 0.0 8.3e-45 152.5 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 CDJ91794.1 - 1.2e-33 115.9 2.5 2.1e-33 115.1 2.5 1.4 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 CDJ91794.1 - 0.049 13.6 12.9 0.56 10.2 11.0 2.3 1 1 1 2 2 2 0 Ion channel Astacin PF01400.24 CDJ91795.1 - 8.1e-69 231.1 0.5 1.2e-68 230.5 0.5 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 CDJ91795.1 - 0.00013 21.8 0.3 0.066 13.1 0.0 2.5 2 0 0 2 2 2 2 Matrixin Reprolysin_4 PF13583.6 CDJ91795.1 - 0.00067 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 CDJ91795.1 - 0.028 13.4 0.1 0.05 12.6 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_5 PF13688.6 CDJ91795.1 - 0.045 13.9 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 CDJ91795.1 - 0.077 12.9 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 CDJ91795.1 - 0.083 13.4 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 CDJ91795.1 - 0.24 10.6 0.1 0.39 9.9 0.1 1.3 1 0 0 1 1 1 0 Met-zincin Metallophos PF00149.28 CDJ91797.1 - 1.4e-34 120.4 0.1 1.9e-34 119.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDJ91797.1 - 1.5e-05 25.3 0.0 2.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Globin PF00042.22 CDJ91798.1 - 3e-06 27.8 0.0 7.4e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Globin HHV-1_VABD PF16852.5 CDJ91799.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Herpes viral adaptor-to-host cellular mRNA binding domain Invasin_D3 PF09134.10 CDJ91800.1 - 0.024 15.0 2.4 7.5 6.9 1.7 3.3 3 0 0 3 3 3 0 Invasin, domain 3 EGF PF00008.27 CDJ91800.1 - 0.12 12.7 10.3 0.81 10.0 1.2 2.7 2 1 0 2 2 2 0 EGF-like domain EGF_2 PF07974.13 CDJ91800.1 - 0.49 10.8 16.5 2.4 8.6 5.8 2.6 2 0 0 2 2 2 0 EGF-like domain 7tm_1 PF00001.21 CDJ91802.1 - 8.5e-05 22.0 12.5 8.5e-05 22.0 12.5 2.1 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF5423 PF17461.2 CDJ91802.1 - 0.31 9.8 0.5 0.43 9.4 0.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) SSB PF00436.25 CDJ91803.1 - 1.9e-19 69.6 0.1 2.5e-19 69.2 0.1 1.2 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 CDJ91803.1 - 0.0026 17.7 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain NIPSNAP PF07978.13 CDJ91804.1 - 2.5e-38 130.4 0.4 3.3e-30 104.3 0.2 2.2 2 0 0 2 2 2 2 NIPSNAP V-SNARE_C PF12352.8 CDJ91805.1 - 2.3e-05 24.6 6.0 2.3e-05 24.6 6.0 2.5 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF3450 PF11932.8 CDJ91805.1 - 0.0045 16.3 14.4 0.19 11.0 5.9 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3450) DUF1664 PF07889.12 CDJ91805.1 - 0.035 14.1 8.0 0.18 11.9 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF745 PF05335.13 CDJ91805.1 - 0.055 13.2 12.4 0.39 10.4 3.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF745) SCP2 PF02036.17 CDJ91805.1 - 0.081 13.4 0.4 0.16 12.5 0.4 1.5 1 0 0 1 1 1 0 SCP-2 sterol transfer family Snapin_Pallidin PF14712.6 CDJ91805.1 - 0.089 13.2 17.4 0.55 10.7 3.3 2.4 2 0 0 2 2 2 0 Snapin/Pallidin 5_3_exonuc PF01367.20 CDJ91805.1 - 0.16 12.6 2.2 0.27 11.9 0.1 2.3 2 2 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Spc7 PF08317.11 CDJ91805.1 - 0.21 10.5 12.0 0.032 13.1 3.1 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein FAM176 PF14851.6 CDJ91805.1 - 0.24 11.0 6.6 0.72 9.5 6.6 1.7 1 0 0 1 1 1 0 FAM176 family MCPsignal PF00015.21 CDJ91805.1 - 0.25 11.1 4.8 0.26 11.1 0.5 2.4 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Gly_radical PF01228.21 CDJ91805.1 - 0.37 11.3 3.5 9 6.9 0.0 3.1 3 1 1 4 4 4 0 Glycine radical DUF4110 PF13422.6 CDJ91805.1 - 2.8 8.1 8.1 0.51 10.4 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) DASH_Dad1 PF08649.10 CDJ91805.1 - 3.1 8.0 5.7 5.5 7.3 0.1 3.1 3 0 0 3 3 3 0 DASH complex subunit Dad1 DUF2935 PF11155.8 CDJ91807.1 - 0.0047 17.3 6.8 0.099 13.0 0.1 5.4 5 3 0 5 5 5 1 Domain of unknown function (DUF2935) KASH_CCD PF14662.6 CDJ91807.1 - 0.0081 16.0 0.0 0.0081 16.0 0.0 7.8 3 2 5 8 8 8 1 Coiled-coil region of CCDC155 or KASH Herpes_BLRF2 PF05812.12 CDJ91807.1 - 0.021 15.0 1.9 0.021 15.0 1.9 6.0 5 1 1 6 6 6 0 Herpesvirus BLRF2 protein DUF4951 PF16309.5 CDJ91807.1 - 0.093 12.8 0.0 0.4 10.8 0.0 2.1 1 0 0 1 1 1 0 Domian of unknown function (DUF4951) DUF3130 PF11328.8 CDJ91807.1 - 0.14 12.5 7.9 1.2 9.4 0.1 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3130 YtxH PF12732.7 CDJ91807.1 - 5 7.7 16.2 26 5.4 1.3 5.7 3 2 0 3 3 3 0 YtxH-like protein DUF4363 PF14276.6 CDJ91808.1 - 0.14 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) CD36 PF01130.21 CDJ91810.1 - 6.8e-10 38.1 0.0 7.4e-10 37.9 0.0 1.0 1 0 0 1 1 1 1 CD36 family PEX-1N PF09262.11 CDJ91813.1 - 3.7e-12 46.5 0.0 7.6e-12 45.5 0.0 1.5 2 0 0 2 2 2 1 Peroxisome biogenesis factor 1, N-terminal CAP PF00188.26 CDJ91814.1 - 0.012 16.4 0.0 0.018 15.8 0.0 1.3 1 1 0 1 1 1 0 Cysteine-rich secretory protein family HTH_Tnp_Tc3_2 PF01498.18 CDJ91815.1 - 0.0011 19.2 0.4 0.0015 18.8 0.4 1.2 1 0 0 1 1 1 1 Transposase HTH_Tnp_IS630 PF01710.16 CDJ91815.1 - 0.0078 16.3 0.0 0.0098 15.9 0.0 1.2 1 0 0 1 1 1 1 Transposase HTH_50 PF18024.1 CDJ91815.1 - 0.016 14.8 0.1 0.032 13.8 0.0 1.5 2 0 0 2 2 2 0 Helix-turn-helix domain DUF488 PF04343.13 CDJ91815.1 - 0.078 13.6 0.0 0.091 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF488 AbiEi_4 PF13338.6 CDJ91815.1 - 0.086 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin HTH_38 PF13936.6 CDJ91815.1 - 0.087 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Flavi_NS4A PF01350.17 CDJ91816.1 - 0.09 12.7 0.6 0.14 12.0 0.6 1.3 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A TTC5_OB PF16669.5 CDJ91817.1 - 4.3e-27 94.1 0.1 6.7e-27 93.5 0.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat protein 5 OB fold domain TPR_11 PF13414.6 CDJ91817.1 - 8.6e-08 31.7 1.6 0.043 13.5 0.3 4.0 3 1 1 4 4 4 2 TPR repeat TPR_1 PF00515.28 CDJ91817.1 - 2.4e-06 27.1 4.9 0.045 13.6 0.7 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ91817.1 - 6.9e-05 22.7 6.0 0.0084 16.2 1.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ91817.1 - 0.0063 17.1 0.2 2.2 9.0 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ91817.1 - 0.086 13.7 0.8 8 7.6 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ91817.1 - 0.22 12.0 1.0 11 6.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ91817.1 - 0.38 11.1 4.2 2.5 8.5 0.2 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.25 CDJ91819.1 - 5.5e-62 209.5 0.0 6.6e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ91819.1 - 1.5e-41 142.4 0.0 1.8e-41 142.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ91819.1 - 3.5e-06 26.1 0.0 9.7e-05 21.3 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CDJ91819.1 - 6.6e-06 25.7 0.1 8.2e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CDJ91819.1 - 0.056 12.4 0.1 0.075 12.0 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 CDJ91819.1 - 0.067 12.8 0.4 0.17 11.5 0.2 1.8 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 CDJ91819.1 - 0.077 12.6 0.3 0.11 12.0 0.3 1.2 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 CDJ91819.1 - 0.15 11.4 0.2 0.22 10.8 0.2 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ91819.1 - 0.19 11.6 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Methyltransf_31 PF13847.6 CDJ91820.1 - 5e-19 68.6 0.3 2.6e-18 66.3 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ91820.1 - 1e-15 58.2 0.1 1.8e-15 57.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ91820.1 - 1.8e-15 57.3 0.1 3e-15 56.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ91820.1 - 2.4e-13 50.7 0.1 3.8e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ91820.1 - 2.7e-12 46.8 0.0 4.3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ91820.1 - 2.1e-05 24.0 0.7 0.00044 19.6 0.2 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 CDJ91820.1 - 3e-05 23.6 0.0 4.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 CDJ91820.1 - 9e-05 22.0 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_2 PF00891.18 CDJ91820.1 - 0.00012 21.4 0.4 0.00021 20.7 0.1 1.5 2 0 0 2 2 2 1 O-methyltransferase domain CMAS PF02353.20 CDJ91820.1 - 0.00018 20.9 0.4 0.00039 19.8 0.0 1.8 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase DREV PF05219.12 CDJ91820.1 - 0.00021 20.5 0.0 0.00033 19.9 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase NodS PF05401.11 CDJ91820.1 - 0.00055 19.6 0.0 0.00074 19.2 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) PCMT PF01135.19 CDJ91820.1 - 0.00083 19.2 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 CDJ91820.1 - 0.00092 18.7 0.1 0.0013 18.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 CDJ91820.1 - 0.001 19.1 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CDJ91820.1 - 0.0024 16.9 0.0 0.003 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.15 CDJ91820.1 - 0.0031 17.2 0.1 0.015 15.0 0.0 1.9 1 1 1 2 2 2 1 Conserved hypothetical protein 95 Pox_MCEL PF03291.16 CDJ91820.1 - 0.015 14.5 0.5 0.15 11.1 0.5 2.1 1 1 0 1 1 1 0 mRNA capping enzyme MetW PF07021.12 CDJ91820.1 - 0.021 14.4 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 CDJ91820.1 - 0.032 14.2 0.0 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DUF3052 PF11253.8 CDJ91820.1 - 0.05 13.5 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) Methyltransf_19 PF04672.12 CDJ91820.1 - 0.095 12.2 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl methyltransferase zf-C3HC4_3 PF13920.6 CDJ91821.1 - 2e-07 30.8 18.5 3.4e-07 30.0 18.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDJ91821.1 - 4.4e-05 23.3 14.4 7.6e-05 22.5 14.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 ATG16 PF08614.11 CDJ91821.1 - 0.00043 20.6 41.9 0.00078 19.7 18.0 2.5 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) APG6_N PF17675.1 CDJ91821.1 - 0.019 15.5 48.3 8 7.0 22.0 2.9 1 1 1 2 2 2 0 Apg6 coiled-coil region GAS PF13851.6 CDJ91821.1 - 0.029 13.7 43.1 0.42 9.9 25.8 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.9 CDJ91821.1 - 0.037 14.3 1.3 0.037 14.3 1.3 4.0 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.9 CDJ91821.1 - 0.043 13.8 46.5 0.061 13.3 21.1 3.7 2 1 2 4 4 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.11 CDJ91821.1 - 0.18 12.1 11.3 0.13 12.6 0.6 3.2 4 0 0 4 4 3 0 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 CDJ91821.1 - 0.41 11.1 39.8 0.12 12.8 11.5 2.3 1 1 1 2 2 2 0 Fez1 YcgR PF07317.12 CDJ91821.1 - 0.48 10.3 3.6 0.36 10.7 1.0 2.0 2 0 0 2 2 2 0 Flagellar regulator YcgR Laminin_II PF06009.12 CDJ91821.1 - 0.51 10.4 21.3 0.027 14.5 9.0 2.5 1 1 1 2 2 2 0 Laminin Domain II Troponin PF00992.20 CDJ91821.1 - 0.69 10.2 42.6 3.2 8.1 14.9 2.5 1 1 1 2 2 2 0 Troponin Taxilin PF09728.9 CDJ91821.1 - 1.3 8.1 41.4 0.73 8.9 14.5 2.4 1 1 1 2 2 2 0 Myosin-like coiled-coil protein BRE1 PF08647.11 CDJ91821.1 - 1.5 8.9 34.1 0.071 13.2 5.8 4.2 1 1 2 4 4 4 0 BRE1 E3 ubiquitin ligase Seryl_tRNA_N PF02403.22 CDJ91821.1 - 1.6 9.0 34.0 9.4 6.5 8.4 4.0 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF812 PF05667.11 CDJ91821.1 - 1.9 7.3 38.0 4.4 6.1 38.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) SYCE1 PF15233.6 CDJ91821.1 - 2.2 8.3 37.6 0.64 10.1 34.0 1.8 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 Spc7 PF08317.11 CDJ91821.1 - 2.4 7.0 41.3 18 4.1 38.2 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 CDJ91821.1 - 2.4 8.2 20.0 1.5 8.9 4.9 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 CDJ91821.1 - 3.6 6.1 33.0 18 3.8 33.0 1.9 1 1 0 1 1 1 0 AAA domain Tho2 PF11262.8 CDJ91821.1 - 4.4 6.4 27.3 0.81 8.8 10.3 2.3 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 MAD PF05557.13 CDJ91821.1 - 4.7 5.5 41.9 6.4 5.0 39.9 1.9 1 1 0 1 1 1 0 Mitotic checkpoint protein Med21 PF11221.8 CDJ91821.1 - 5.6 7.2 36.2 1.2 9.4 17.8 3.3 2 1 1 3 3 3 0 Subunit 21 of Mediator complex DUF4472 PF14739.6 CDJ91821.1 - 6.6 7.5 32.1 2.9 8.7 13.1 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4472) ADIP PF11559.8 CDJ91821.1 - 7.7 6.6 47.9 3.4 7.7 16.5 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding SHE3 PF17078.5 CDJ91821.1 - 8.2 6.1 35.9 0.27 10.9 7.5 2.8 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 DUF4795 PF16043.5 CDJ91821.1 - 8.8 5.9 31.2 55 3.3 5.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Molybdopterin PF00384.22 CDJ91822.1 - 0.043 12.8 0.0 0.057 12.4 0.0 1.1 1 0 0 1 1 1 0 Molybdopterin oxidoreductase DnaJ PF00226.31 CDJ91823.1 - 9.7e-24 83.3 0.9 2.9e-23 81.7 0.9 1.9 1 0 0 1 1 1 1 DnaJ domain LMBR1 PF04791.16 CDJ91823.1 - 0.00052 19.1 0.1 0.00056 18.9 0.1 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein HSP70 PF00012.20 CDJ91823.1 - 0.1 10.8 0.0 0.17 10.0 0.0 1.3 1 0 0 1 1 1 0 Hsp70 protein DUF4500 PF14937.6 CDJ91824.1 - 0.0024 17.8 0.1 0.0032 17.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4500) DUF4051 PF13260.6 CDJ91824.1 - 0.25 11.1 0.3 0.25 11.1 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) Nitroreductase PF00881.24 CDJ91826.1 - 0.089 12.8 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Nitroreductase family Ldl_recept_a PF00057.18 CDJ91827.1 - 1.3e-44 150.1 77.8 7.6e-12 45.2 16.9 5.3 4 1 0 4 4 4 4 Low-density lipoprotein receptor domain class A DDE_3 PF13358.6 CDJ91828.1 - 0.0057 16.4 0.1 0.0086 15.8 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF2760 PF10816.8 CDJ91828.1 - 0.095 12.5 0.0 0.18 11.7 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2760) TRAP-gamma PF07074.12 CDJ91829.1 - 1.2e-51 174.7 4.7 1.3e-51 174.5 4.7 1.0 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF3270 PF11674.8 CDJ91829.1 - 0.00022 21.3 1.6 0.00039 20.5 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3270) NMN_transporter PF04973.12 CDJ91829.1 - 0.029 14.3 2.5 0.7 9.8 0.2 2.1 2 0 0 2 2 2 0 Nicotinamide mononucleotide transporter DUF2207 PF09972.9 CDJ91829.1 - 0.052 12.3 2.0 0.054 12.3 2.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pardaxin PF07425.11 CDJ91829.1 - 0.061 12.9 0.5 0.18 11.5 0.1 1.9 2 0 0 2 2 2 0 Pardaxin TUDOR PF00567.24 CDJ91830.1 - 0.00012 22.0 0.1 0.00018 21.5 0.1 1.3 1 0 0 1 1 1 1 Tudor domain UCH PF00443.29 CDJ91831.1 - 4.5e-49 167.3 0.1 6.8e-49 166.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ91831.1 - 6.2e-34 118.0 0.0 1.7e-33 116.6 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UPF0183 PF03676.14 CDJ91831.1 - 0.016 14.5 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0183) zf_UBZ PF18439.1 CDJ91831.1 - 0.62 9.7 2.5 4.1 7.1 0.4 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Exo_endo_phos PF03372.23 CDJ91832.1 - 4.1e-10 39.6 0.1 8.3e-10 38.6 0.1 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CDJ91832.1 - 7.1e-09 35.5 0.1 1.6e-08 34.4 0.1 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF3847 PF12958.7 CDJ91832.1 - 0.016 15.3 1.4 0.034 14.3 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) TFIIS_M PF07500.14 CDJ91833.1 - 3.3e-30 104.8 0.4 3.3e-30 104.8 0.4 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 CDJ91833.1 - 1.3e-18 66.5 5.8 2.1e-18 65.8 5.8 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 CDJ91833.1 - 3.9e-14 52.4 5.0 9.1e-14 51.2 5.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Ku_C PF03730.14 CDJ91833.1 - 0.0011 19.6 2.1 0.0029 18.3 2.1 1.7 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm DUF3585 PF12130.8 CDJ91833.1 - 0.042 14.0 2.3 4 7.6 0.0 2.3 2 0 0 2 2 2 0 Bivalent Mical/EHBP Rab binding domain Rotamase PF00639.21 CDJ91833.1 - 1.2 10.1 3.6 1 10.3 1.4 2.0 2 0 0 2 2 2 0 PPIC-type PPIASE domain PAX PF00292.18 CDJ91834.1 - 9.9e-47 158.0 0.6 1.4e-46 157.5 0.6 1.2 1 0 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 CDJ91834.1 - 5.1e-22 77.5 5.6 8.3e-22 76.8 2.9 2.3 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CDJ91834.1 - 9.1e-09 35.1 0.4 2.9e-08 33.5 0.1 2.1 2 1 0 2 2 2 1 Homeobox KN domain HTH_29 PF13551.6 CDJ91834.1 - 1.3e-07 31.5 0.1 5.8e-05 23.0 0.0 2.9 3 0 0 3 3 3 1 Winged helix-turn helix HTH_23 PF13384.6 CDJ91834.1 - 3.6e-07 29.8 0.1 1.2e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 CDJ91834.1 - 0.0025 18.4 0.2 2.4 8.8 0.0 3.2 2 1 1 3 3 3 2 Homeodomain-like domain HTH_28 PF13518.6 CDJ91834.1 - 0.011 15.8 0.1 0.1 12.7 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 CDJ91834.1 - 0.023 14.1 0.1 2.4 7.6 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 MarR_2 PF12802.7 CDJ91834.1 - 0.047 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_Tnp_IS1 PF12759.7 CDJ91834.1 - 0.2 11.3 0.2 0.57 9.8 0.0 1.8 2 0 0 2 2 2 0 InsA C-terminal domain DUF1323 PF07037.11 CDJ91834.1 - 0.46 10.9 3.5 0.4 11.1 0.2 2.4 2 1 0 3 3 3 0 Putative transcription regulator (DUF1323) UPF0114 PF03350.16 CDJ91835.1 - 0.17 12.1 2.0 0.37 11.0 1.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 DUF2834 PF11196.8 CDJ91835.1 - 0.19 12.1 0.3 0.19 12.1 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2834) Syntaxin_2 PF14523.6 CDJ91836.1 - 0.0017 18.7 0.8 0.0021 18.4 0.8 1.1 1 0 0 1 1 1 1 Syntaxin-like protein DUF3124 PF11322.8 CDJ91836.1 - 0.11 12.7 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3124) Cyclin_N PF00134.23 CDJ91837.1 - 8.5e-06 25.5 3.3 0.00053 19.7 3.3 2.5 1 1 0 1 1 1 1 Cyclin, N-terminal domain HMG_box PF00505.19 CDJ91838.1 - 1.7e-10 41.1 0.1 5.1e-10 39.6 0.1 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ91838.1 - 3.8e-05 24.2 1.9 4.6e-05 23.9 0.2 2.1 2 0 0 2 2 2 1 HMG-box domain DUF812 PF05667.11 CDJ91838.1 - 0.0093 14.9 7.1 0.012 14.6 7.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Prp19 PF08606.11 CDJ91838.1 - 0.087 12.8 0.7 0.24 11.4 0.7 1.7 1 0 0 1 1 1 0 Prp19/Pso4-like CorA PF01544.18 CDJ91838.1 - 0.36 10.1 4.1 6.7 5.9 0.4 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein TMF_TATA_bd PF12325.8 CDJ91838.1 - 1 9.6 9.0 0.11 12.7 1.0 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.8 CDJ91838.1 - 1.1 8.5 8.5 0.16 11.3 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 CDJ91838.1 - 4.6 7.8 16.4 41 4.7 2.9 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF3987 PF13148.6 CDJ91838.1 - 6 5.8 9.6 0.78 8.7 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) ETF PF01012.21 CDJ91839.1 - 7.6e-46 156.3 2.1 9.7e-46 155.9 2.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Snf7 PF03357.21 CDJ91840.1 - 2.2e-18 66.4 10.9 3.1e-18 65.9 10.9 1.2 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 CDJ91840.1 - 0.0005 20.0 8.2 0.00067 19.6 8.2 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway ArAE_1_C PF11728.8 CDJ91840.1 - 0.32 11.0 6.5 0.84 9.6 5.2 2.1 1 1 1 2 2 2 0 Putative aromatic acid exporter C-terminal domain DUF4795 PF16043.5 CDJ91840.1 - 0.46 10.1 12.2 0.057 13.0 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF4813 PF16072.5 CDJ91840.1 - 0.5 10.0 4.1 0.089 12.4 0.6 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) Ribosomal_L13e PF01294.18 CDJ91841.1 - 1.9e-76 255.9 4.8 2.8e-76 255.4 4.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e p25-alpha PF05517.12 CDJ91842.1 - 1.4e-45 155.2 8.3 1.7e-45 155.0 8.3 1.0 1 0 0 1 1 1 1 p25-alpha Bax1-I PF01027.20 CDJ91844.1 - 5e-25 88.5 41.3 5.8e-25 88.3 41.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Glycophorin_A PF01102.18 CDJ91844.1 - 1.1 9.5 5.5 3.1 8.0 0.1 2.6 2 0 0 2 2 2 0 Glycophorin A PIRT PF15099.6 CDJ91844.1 - 2.2 7.8 5.0 3.7 7.2 0.5 2.4 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Transposase_1 PF01359.18 CDJ91845.1 - 0.097 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Transposase (partial DDE domain) ABC2_membrane_3 PF12698.7 CDJ91847.1 - 1.2e-23 83.8 31.8 1.9e-23 83.1 31.8 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 CDJ91847.1 - 7e-21 75.2 0.0 1.1e-20 74.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CDJ91847.1 - 1.7e-11 44.5 0.0 3e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CDJ91847.1 - 0.025 15.1 0.2 0.045 14.2 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CDJ91847.1 - 0.17 11.7 0.1 0.45 10.3 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 CDJ91847.1 - 0.19 11.1 0.0 7.7 5.9 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CDJ91847.1 - 0.27 10.9 0.0 4.5 6.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Spo12 PF05032.12 CDJ91848.1 - 0.00033 20.5 1.8 0.00053 19.8 0.4 2.1 3 0 0 3 3 3 1 Spo12 family BRO1 PF03097.18 CDJ91849.1 - 1e-81 274.8 5.4 1.8e-81 273.9 5.4 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CDJ91849.1 - 1.7e-43 149.0 15.1 1.7e-43 149.0 15.1 3.0 4 0 0 4 4 4 1 ALIX V-shaped domain binding to HIV Unstab_antitox PF09720.10 CDJ91849.1 - 0.11 12.5 1.2 8.6 6.5 0.0 2.9 2 0 0 2 2 2 0 Putative addiction module component CAAD PF14159.6 CDJ91850.1 - 0.013 15.3 0.3 0.031 14.1 0.3 1.6 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF3754 PF12576.8 CDJ91850.1 - 0.055 13.4 1.0 1.1 9.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3754) ABC_membrane_3 PF13748.6 CDJ91850.1 - 1.7 7.8 6.3 1.7 7.8 1.1 2.4 3 0 0 3 3 3 0 ABC transporter transmembrane region SET PF00856.28 CDJ91851.1 - 1.2e-22 81.1 0.1 5.4e-22 79.0 0.0 2.2 2 0 0 2 2 2 1 SET domain Pre-SET PF05033.16 CDJ91851.1 - 1.8e-16 60.8 8.6 1.8e-16 60.8 8.6 2.7 3 0 0 3 3 3 1 Pre-SET motif MBD PF01429.19 CDJ91851.1 - 4.5e-08 32.7 0.0 1.2e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Methyl-CpG binding domain TUDOR_5 PF18359.1 CDJ91851.1 - 2.1e-07 30.5 0.0 4.9e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 Hydantoinase_B PF02538.14 CDJ91851.1 - 0.094 11.1 1.0 0.14 10.5 0.3 1.5 2 0 0 2 2 2 0 Hydantoinase B/oxoprolinase SBF PF01758.16 CDJ91852.1 - 1.6e-32 112.8 16.7 3e-32 111.9 16.7 1.5 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 CDJ91852.1 - 6.3e-11 42.2 15.0 9.7e-11 41.5 15.0 1.3 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) LMBR1 PF04791.16 CDJ91853.1 - 8.3e-85 285.6 34.3 1.5e-84 284.8 34.3 1.4 1 1 0 1 1 1 1 LMBR1-like membrane protein DUF3774 PF12609.8 CDJ91854.1 - 2.9 9.0 7.1 0.6 11.2 2.8 1.9 2 0 0 2 2 2 0 Wound-induced protein Collagen PF01391.18 CDJ91855.1 - 5.7e-26 90.1 85.6 1.8e-09 37.2 27.0 4.2 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ91855.1 - 4.2e-11 42.7 0.1 5.7e-11 42.3 0.1 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Peptidase_M1_N PF17900.1 CDJ91856.1 - 1.7e-08 34.9 0.0 4.1e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 CDJ91856.1 - 3.9e-06 26.6 0.5 1.2e-05 25.1 0.5 1.8 1 1 0 1 1 1 1 Peptidase family M1 domain SOG2 PF10428.9 CDJ91856.1 - 0.062 12.5 8.9 0.088 12.0 8.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein EB PF01683.18 CDJ91857.1 - 1.4e-16 60.5 19.3 8.1e-10 38.8 1.3 3.1 3 0 0 3 3 3 3 EB module Dickkopf_N PF04706.12 CDJ91857.1 - 0.11 12.9 0.4 0.11 12.9 0.4 3.4 3 0 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region CRAL_TRIO PF00650.20 CDJ91858.1 - 3.6e-16 59.3 0.0 5.7e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain DUF1409 PF07197.12 CDJ91858.1 - 0.026 14.4 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) MRP-S34 PF16053.5 CDJ91859.1 - 3.7e-38 130.1 0.0 5e-38 129.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 CCSAP PF15748.5 CDJ91860.1 - 0.0087 16.3 6.6 0.016 15.4 6.6 1.3 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated gag-asp_proteas PF13975.6 CDJ91861.1 - 3.6e-08 33.9 0.0 7.8e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ91861.1 - 5.4e-08 33.4 0.0 2.1e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease rve PF00665.26 CDJ91861.1 - 6.3e-07 29.6 0.0 1.9e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVP PF00077.20 CDJ91861.1 - 0.003 17.8 0.0 0.007 16.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1539 PF07560.11 CDJ91861.1 - 0.0077 16.3 0.1 3.8 7.6 0.0 2.9 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1539) rve_3 PF13683.6 CDJ91861.1 - 0.0096 15.7 0.0 0.044 13.6 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain DUF2845 PF11006.8 CDJ91861.1 - 0.019 15.0 0.1 0.046 13.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2845) eIF3g PF12353.8 CDJ91861.1 - 0.025 14.9 1.8 0.077 13.4 0.4 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G DUF3398 PF11878.8 CDJ91861.1 - 0.11 12.9 1.7 11 6.5 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3398) Asp_protease PF09668.10 CDJ91861.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Ank_2 PF12796.7 CDJ91862.1 - 3.5e-51 171.7 15.0 2.9e-10 40.6 0.1 6.2 4 2 3 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ91862.1 - 4.7e-39 132.3 10.7 1.1e-06 29.1 0.0 9.5 4 4 6 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ91862.1 - 1.3e-32 111.4 10.7 2.7e-07 30.7 0.2 10.1 4 4 5 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ91862.1 - 5.6e-31 103.1 2.7 0.026 15.0 0.0 11.0 10 0 0 10 10 10 6 Ankyrin repeat Ank PF00023.30 CDJ91862.1 - 1e-22 79.5 12.5 0.071 13.6 0.3 9.5 10 0 0 10 10 8 7 Ankyrin repeat Dpy-30 PF05186.13 CDJ91862.1 - 2.3e-10 40.0 0.0 6.8e-10 38.5 0.0 1.9 1 0 0 1 1 1 1 Dpy-30 motif GATase_7 PF13537.6 CDJ91862.1 - 4e-08 33.2 0.2 1.1 9.2 0.0 5.7 3 1 2 5 5 5 2 Glutamine amidotransferase domain Cytochrom_B562 PF07361.11 CDJ91862.1 - 7.7e-08 32.9 0.7 0.021 15.5 0.0 3.6 3 0 0 3 3 3 2 Cytochrome b562 DUF1843 PF08898.10 CDJ91862.1 - 9.4e-08 32.4 2.9 0.09 13.3 0.1 5.5 5 1 0 5 5 5 2 Domain of unknown function (DUF1843) DNA_pol3_a_NI PF14480.6 CDJ91862.1 - 0.13 12.2 0.1 23 5.0 0.0 3.1 3 0 0 3 3 3 0 DNA polymerase III polC-type N-terminus I DUF2520 PF10728.9 CDJ91862.1 - 0.54 10.0 2.3 18 5.1 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF2520) JmjN PF02375.17 CDJ91863.1 - 0.16 11.9 0.0 14 5.7 0.0 2.4 2 0 0 2 2 2 0 jmjN domain RabGAP-TBC PF00566.18 CDJ91864.1 - 3.2e-26 92.3 3.5 7.9e-25 87.8 3.5 2.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Abhydrolase_1 PF00561.20 CDJ91864.1 - 0.084 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3715 PF12509.8 CDJ91865.1 - 5.1e-10 39.5 0.0 1.1e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3715) PPI_Ypi1 PF07491.11 CDJ91865.1 - 0.0039 17.0 0.1 0.01 15.6 0.1 1.7 1 0 0 1 1 1 1 Protein phosphatase inhibitor Ldh_1_N PF00056.23 CDJ91867.1 - 6e-30 104.2 0.0 9.5e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CDJ91867.1 - 3e-24 85.8 0.0 4.3e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4C PF11975.8 CDJ91867.1 - 0.13 12.3 0.0 0.52 10.4 0.0 1.8 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase C-terminal domain Ldh_1_N PF00056.23 CDJ91868.1 - 9.5e-46 155.4 0.2 1.2e-45 155.0 0.2 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CDJ91868.1 - 2.7e-06 27.4 0.1 3.1e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 CDJ91868.1 - 0.023 14.3 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase SCVP PF17619.2 CDJ91869.1 - 4e-24 85.3 0.5 4.7e-24 85.1 0.5 1.1 1 0 0 1 1 1 1 Secreted clade V proteins Pkinase PF00069.25 CDJ91872.1 - 6.6e-56 189.6 0.0 8.5e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ91872.1 - 2.9e-21 75.9 0.0 3.7e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ91872.1 - 3.3e-07 29.9 0.0 4.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDJ91872.1 - 9.2e-05 21.9 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDJ91872.1 - 0.0029 16.5 0.1 0.005 15.7 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase MbeD_MobD PF04899.12 CDJ91873.1 - 0.013 15.6 13.3 0.022 14.8 1.8 2.9 3 0 0 3 3 3 0 MbeD/MobD like TetR_C_4 PF08359.11 CDJ91873.1 - 0.16 12.1 5.2 0.047 13.9 2.1 1.7 2 0 0 2 2 2 0 YsiA-like protein, C-terminal region NYD-SP28_assoc PF14775.6 CDJ91873.1 - 0.59 10.3 17.7 1.2 9.3 1.7 4.1 3 1 0 3 3 3 0 Sperm tail C-terminal domain Prominin PF05478.11 CDJ91873.1 - 1.2 7.0 10.1 1.7 6.5 10.1 1.3 1 0 0 1 1 1 0 Prominin Phage_GP20 PF06810.11 CDJ91873.1 - 1.4 8.7 13.2 1.5 8.6 1.0 3.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 Fib_alpha PF08702.10 CDJ91873.1 - 1.7 8.8 16.1 0.23 11.7 9.6 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 CDJ91873.1 - 1.8 9.1 52.8 1 9.9 15.9 3.4 1 1 2 3 3 3 0 Apg6 coiled-coil region ApoLp-III PF07464.11 CDJ91873.1 - 1.9 8.6 10.5 3.4 7.7 1.6 2.6 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) PRKG1_interact PF15898.5 CDJ91873.1 - 2.2 9.2 43.7 0.18 12.7 15.3 3.6 1 1 3 4 4 4 0 cGMP-dependent protein kinase interacting domain LCIB_C_CA PF18599.1 CDJ91873.1 - 2.5 7.4 4.7 1.6 8.0 2.4 1.7 1 1 1 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Baculo_PEP_C PF04513.12 CDJ91873.1 - 3.4 7.7 11.9 3.5 7.7 3.1 2.5 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus WD40_alt PF14077.6 CDJ91873.1 - 4.3 7.3 6.3 18 5.3 0.0 3.4 3 0 0 3 3 3 0 Alternative WD40 repeat motif Lectin_N PF03954.14 CDJ91873.1 - 4.5 7.0 9.6 0.28 10.9 1.1 2.6 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain DUF2353 PF09789.9 CDJ91873.1 - 5.3 6.3 38.5 0.32 10.3 25.5 2.1 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DUF4407 PF14362.6 CDJ91873.1 - 5.8 6.2 29.1 3.8e+02 0.2 29.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 CDJ91873.1 - 5.8 7.2 10.7 13 6.1 1.4 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4201 PF13870.6 CDJ91873.1 - 8.2 6.1 36.5 24 4.6 9.8 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) Tweety PF04906.13 CDJ91873.1 - 8.7 4.9 8.8 6.6 5.3 0.9 2.2 1 1 1 2 2 2 0 Tweety Cation_efflux PF01545.21 CDJ91874.1 - 1.7e-21 76.9 8.0 2e-21 76.6 8.0 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 CDJ91874.1 - 6.8e-11 42.1 1.2 1.3e-10 41.3 1.2 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Voltage_CLC PF00654.20 CDJ91874.1 - 0.026 13.8 1.1 0.059 12.6 1.1 1.6 1 1 0 1 1 1 0 Voltage gated chloride channel Kazal_2 PF07648.15 CDJ91875.1 - 2.1e-12 46.9 11.2 2.1e-12 46.9 11.2 2.1 2 1 0 2 2 2 1 Kazal-type serine protease inhibitor domain FOLN PF09289.10 CDJ91875.1 - 3.8e-06 27.0 9.5 3.8e-06 27.0 9.5 2.3 3 0 0 3 3 3 1 Follistatin/Osteonectin-like EGF domain SPARC_Ca_bdg PF10591.9 CDJ91875.1 - 0.0075 16.6 0.1 0.0075 16.6 0.1 2.2 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_1 PF00050.21 CDJ91875.1 - 0.029 14.4 10.7 0.093 12.8 10.7 1.9 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain UDPG_MGDP_dh_N PF03721.14 CDJ91875.1 - 0.069 12.7 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Tyrosinase PF00264.20 CDJ91876.1 - 6.4e-07 29.9 0.5 1.4e-06 28.8 0.5 1.6 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF1057 PF06342.12 CDJ91877.1 - 4.3e-81 272.2 0.0 5e-81 272.0 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_6 PF12697.7 CDJ91877.1 - 7.5e-10 39.8 0.0 1e-09 39.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDJ91877.1 - 3.3e-09 36.8 0.1 1.1e-08 35.1 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ91877.1 - 5e-09 35.8 0.0 1.2e-08 34.5 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 CDJ91877.1 - 0.0026 16.7 0.0 0.0041 16.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Thioesterase PF00975.20 CDJ91877.1 - 0.0038 17.4 0.0 0.099 12.7 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_5 PF12695.7 CDJ91877.1 - 0.027 14.3 0.0 0.59 9.9 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Chlorophyllase PF07224.11 CDJ91877.1 - 0.067 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase DUF1749 PF08538.10 CDJ91877.1 - 0.15 11.2 0.0 0.49 9.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) DUF1057 PF06342.12 CDJ91878.1 - 8.7e-78 261.4 0.0 9.8e-78 261.2 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Hydrolase_4 PF12146.8 CDJ91878.1 - 9.2e-11 41.5 0.0 2.6e-10 40.0 0.0 1.8 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ91878.1 - 6.2e-10 39.2 0.0 1.2e-09 38.2 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ91878.1 - 3.6e-06 27.7 0.0 4.9e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 CDJ91878.1 - 0.0026 16.7 0.0 0.0056 15.6 0.0 1.5 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 CDJ91878.1 - 0.012 14.6 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase ACDC PF14733.6 CDJ91878.1 - 0.15 12.4 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 AP2-coincident C-terminal Abhydrolase_5 PF12695.7 CDJ91878.1 - 0.16 11.7 0.1 1 9.1 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family BAR_3_WASP_bdg PF10456.9 CDJ91879.1 - 2e-19 70.0 4.1 2.2e-19 69.9 4.1 1.0 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein Vps5 PF09325.10 CDJ91879.1 - 0.0024 17.4 1.3 0.0036 16.9 1.3 1.4 1 1 0 1 1 1 1 Vps5 C terminal like DUF3896 PF13035.6 CDJ91879.1 - 0.007 16.5 1.2 0.03 14.5 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3896) Nudc_N PF14050.6 CDJ91879.1 - 0.0094 15.9 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. PurS PF02700.14 CDJ91879.1 - 0.011 15.9 0.1 0.018 15.2 0.1 1.4 1 1 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase TolA_bind_tri PF16331.5 CDJ91879.1 - 0.012 15.7 0.2 0.016 15.2 0.2 1.4 1 1 0 1 1 1 0 TolA binding protein trimerisation BAR PF03114.18 CDJ91879.1 - 0.013 15.1 2.3 0.015 14.9 2.3 1.1 1 0 0 1 1 1 0 BAR domain GP52 PF17468.2 CDJ91880.1 - 0.056 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Phage gene product 52 G_glu_transpept PF01019.21 CDJ91881.1 - 1.6e-11 43.7 0.0 1.8e-11 43.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Tat PF00539.18 CDJ91882.1 - 0.088 13.0 0.3 0.14 12.3 0.0 1.6 2 0 0 2 2 2 0 Transactivating regulatory protein (Tat) PrmA PF06325.13 CDJ91885.1 - 9.2e-10 38.4 0.0 1.6e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CDJ91885.1 - 1e-08 35.8 0.0 2e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ91885.1 - 1.9e-07 31.6 0.0 4.3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ91885.1 - 2.8e-05 23.7 0.1 4.6e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 CDJ91885.1 - 7e-05 22.7 0.0 9.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CDJ91885.1 - 0.00026 21.0 0.0 0.00042 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ91885.1 - 0.00062 20.5 0.0 0.0011 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 CDJ91885.1 - 0.00093 19.0 0.1 0.0015 18.3 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 CDJ91885.1 - 0.00093 19.1 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 CDJ91885.1 - 0.0028 17.4 0.3 0.028 14.2 0.0 2.1 2 0 0 2 2 2 1 Lysine methyltransferase DOT1 PF08123.13 CDJ91885.1 - 0.01 15.4 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_24 PF13578.6 CDJ91885.1 - 0.011 16.7 0.0 0.021 15.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 CDJ91885.1 - 0.016 15.1 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Cons_hypoth95 PF03602.15 CDJ91885.1 - 0.017 14.8 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_9 PF08003.11 CDJ91885.1 - 0.026 13.5 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) CARDB PF07705.11 CDJ91885.1 - 0.031 14.5 0.0 0.081 13.2 0.0 1.7 1 0 0 1 1 1 0 CARDB HTH_26 PF13443.6 CDJ91886.1 - 0.00024 21.5 0.1 0.00043 20.7 0.1 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_IclR PF09339.10 CDJ91886.1 - 0.0028 17.4 0.1 0.0045 16.7 0.1 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 CDJ91886.1 - 0.006 16.5 0.1 0.013 15.4 0.1 1.6 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 CDJ91886.1 - 0.0076 15.8 0.0 0.054 13.1 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding CENP-B_N PF04218.13 CDJ91886.1 - 0.014 15.0 0.0 0.026 14.2 0.0 1.5 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_Tnp_ISL3 PF13542.6 CDJ91886.1 - 0.022 14.2 0.1 0.055 12.9 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_32 PF13565.6 CDJ91886.1 - 0.027 15.1 1.8 0.18 12.4 0.3 2.2 2 0 0 2 2 2 0 Homeodomain-like domain HTH_3 PF01381.22 CDJ91886.1 - 0.033 14.2 0.0 0.056 13.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix DUF3602 PF12223.8 CDJ91886.1 - 0.035 14.7 0.2 0.054 14.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) LacI PF00356.21 CDJ91886.1 - 0.036 13.9 0.9 0.15 11.9 0.1 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family DUF4572 PF15139.6 CDJ91886.1 - 0.13 12.1 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4572) HTH_10 PF04967.12 CDJ91886.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain FH2 PF02181.23 CDJ91887.1 - 9.8e-43 146.7 2.5 1.8e-42 145.8 2.5 1.4 1 0 0 1 1 1 1 Formin Homology 2 Domain DUF4129 PF13559.6 CDJ91887.1 - 0.0066 16.7 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) Ig_2 PF13895.6 CDJ91888.1 - 0.11 12.8 0.2 7 7.1 0.3 3.0 1 1 1 2 2 2 0 Immunoglobulin domain SKG6 PF08693.10 CDJ91888.1 - 4.9 6.6 9.6 12 5.4 9.6 1.7 1 1 0 1 1 1 0 Transmembrane alpha-helix domain DHHC PF01529.20 CDJ91890.1 - 1.3e-37 128.9 11.4 1.3e-37 128.9 11.4 2.3 2 0 0 2 2 2 2 DHHC palmitoyltransferase Ion_trans_2 PF07885.16 CDJ91891.1 - 2.4e-26 91.5 17.9 1.9e-13 50.2 0.1 3.0 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CDJ91891.1 - 2.5e-05 23.7 8.6 0.0029 16.9 0.0 2.5 2 1 0 2 2 2 2 Ion transport protein Spt20 PF12090.8 CDJ91891.1 - 0.018 14.7 0.1 0.023 14.3 0.1 1.1 1 0 0 1 1 1 0 Spt20 family DUF2254 PF10011.9 CDJ91891.1 - 0.096 11.5 4.2 1.3 7.8 0.1 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2254) DUF4592 PF15262.6 CDJ91891.1 - 0.46 11.2 6.4 0.76 10.5 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) DUF1857 PF08982.11 CDJ91892.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) Vps5 PF09325.10 CDJ91895.1 - 1.3e-12 47.8 1.1 1.4e-12 47.6 1.1 1.0 1 0 0 1 1 1 1 Vps5 C terminal like Phage_Mu_Gam PF07352.12 CDJ91895.1 - 0.0055 16.6 0.0 0.0063 16.4 0.0 1.0 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein DUF1351 PF07083.11 CDJ91895.1 - 0.0056 16.5 0.1 0.0057 16.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1351) SPOB_a PF14689.6 CDJ91895.1 - 0.05 13.3 1.3 0.18 11.5 0.3 2.1 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain Qua1 PF16274.5 CDJ91895.1 - 0.092 12.6 0.1 0.15 12.0 0.1 1.4 1 1 0 1 1 1 0 Qua1 domain Sushi PF00084.20 CDJ91899.1 - 2.7e-06 27.9 0.0 4.3e-06 27.2 0.0 1.4 1 1 0 1 1 1 1 Sushi repeat (SCR repeat) Phosphodiest PF01663.22 CDJ91900.1 - 5.3e-14 52.6 0.1 6.9e-14 52.2 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1569 PF07606.11 CDJ91900.1 - 0.17 11.9 0.0 0.4 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1569) CN_hydrolase PF00795.22 CDJ91901.1 - 1.6e-26 93.2 0.0 2.2e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CAAP1 PF15335.6 CDJ91901.1 - 2.4e-08 34.4 0.0 4.2e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Caspase activity and apoptosis inhibitor 1 PseudoU_synth_1 PF01416.20 CDJ91902.1 - 0.0037 17.7 0.1 0.86 10.1 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase Cullin_Nedd8 PF10557.9 CDJ91903.1 - 2.9e-22 78.5 0.8 2.9e-22 78.5 0.8 1.7 2 0 0 2 2 2 1 Cullin protein neddylation domain Cullin PF00888.22 CDJ91903.1 - 0.00024 19.9 0.7 0.00048 18.9 0.1 1.7 2 0 0 2 2 2 1 Cullin family Ribosomal_L6e PF01159.19 CDJ91903.1 - 0.0096 16.5 1.4 0.013 16.0 1.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e SARAF PF06682.12 CDJ91904.1 - 0.014 15.1 0.1 0.019 14.7 0.1 1.3 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Pex14_N PF04695.13 CDJ91904.1 - 0.035 14.8 2.1 0.04 14.6 2.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Prion_bPrPp PF11587.8 CDJ91904.1 - 0.066 13.1 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Major prion protein bPrPp - N terminal DUF1179 PF06678.11 CDJ91904.1 - 0.072 13.1 1.1 0.14 12.2 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1179) DUF4834 PF16118.5 CDJ91904.1 - 0.13 13.2 0.0 0.17 12.9 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Ion_trans PF00520.31 CDJ91906.1 - 0.13 11.5 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Ion transport protein CHAD PF05235.14 CDJ91907.1 - 0.00083 19.4 0.9 0.00088 19.3 0.9 1.1 1 0 0 1 1 1 1 CHAD domain Laminin_II PF06009.12 CDJ91907.1 - 0.0035 17.4 6.2 0.0049 16.9 6.2 1.3 1 0 0 1 1 1 1 Laminin Domain II T3SSipB PF16535.5 CDJ91907.1 - 0.0072 16.8 5.5 0.0095 16.4 5.5 1.3 1 0 0 1 1 1 1 Type III cell invasion protein SipB Macoilin PF09726.9 CDJ91907.1 - 0.084 11.4 9.1 0.091 11.3 9.1 1.0 1 0 0 1 1 1 0 Macoilin family Prominin PF05478.11 CDJ91907.1 - 0.12 10.3 2.5 0.14 10.1 2.5 1.1 1 0 0 1 1 1 0 Prominin FAM76 PF16046.5 CDJ91907.1 - 0.14 11.4 7.8 0.17 11.2 7.8 1.0 1 0 0 1 1 1 0 FAM76 protein TPR_MLP1_2 PF07926.12 CDJ91907.1 - 0.16 12.0 14.3 0.21 11.7 14.3 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 CDJ91907.1 - 0.28 10.0 9.9 0.33 9.8 9.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Uso1_p115_C PF04871.13 CDJ91907.1 - 0.63 10.4 13.8 3.2 8.1 10.4 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region FlaC_arch PF05377.11 CDJ91907.1 - 1.2 9.6 3.9 0.51 10.8 1.2 1.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Tho2 PF11262.8 CDJ91907.1 - 1.8 7.7 6.6 2.3 7.4 6.6 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 YabA PF06156.13 CDJ91907.1 - 2 9.1 5.8 3.5 8.3 5.8 1.5 1 0 0 1 1 1 0 Initiation control protein YabA TMPIT PF07851.13 CDJ91907.1 - 2.9 7.1 5.8 3.8 6.7 5.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF16 PF01519.16 CDJ91907.1 - 3.8 8.1 8.7 17 6.0 8.8 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 zf-CCHC PF00098.23 CDJ91908.1 - 1.2e-06 28.3 2.4 1.2e-06 28.3 2.4 1.8 2 0 0 2 2 2 1 Zinc knuckle gag-asp_proteas PF13975.6 CDJ91908.1 - 7.3e-05 23.3 0.0 0.0002 21.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ91908.1 - 0.031 14.9 0.0 0.091 13.4 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_2 PF13696.6 CDJ91908.1 - 0.044 13.6 1.1 0.044 13.6 1.1 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ91908.1 - 0.14 12.0 0.8 0.31 10.8 0.2 1.9 2 0 0 2 2 2 0 Zinc knuckle DUF4440 PF14534.6 CDJ91909.1 - 0.00012 22.5 0.1 0.00013 22.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF4440 PF14534.6 CDJ91910.1 - 0.00045 20.6 0.5 0.0011 19.4 0.4 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) CAP PF00188.26 CDJ91911.1 - 3.6e-09 37.5 0.2 5.3e-09 37.0 0.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Pkinase_Tyr PF07714.17 CDJ91912.1 - 9.4e-77 257.8 0.0 1.2e-76 257.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ91912.1 - 5.9e-47 160.3 0.0 8.3e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain F5_F8_type_C PF00754.25 CDJ91912.1 - 1.4e-20 73.7 0.0 2.8e-18 66.2 0.0 2.2 2 0 0 2 2 2 1 F5/8 type C domain Haspin_kinase PF12330.8 CDJ91912.1 - 0.00031 19.8 0.0 0.00058 18.9 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CDJ91912.1 - 0.017 14.4 0.0 0.07 12.4 0.0 1.8 1 1 0 1 1 1 0 Kinase-like ELF PF03317.13 CDJ91912.1 - 0.062 13.3 0.0 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 ELF protein RIO1 PF01163.22 CDJ91912.1 - 0.078 12.6 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Reo_sigmaC_M PF17750.1 CDJ91912.1 - 0.085 12.7 0.5 0.21 11.5 0.5 1.7 1 0 0 1 1 1 0 Reovirus sigma C capsid protein triple beta spiral SH3_19 PF18597.1 CDJ91912.1 - 0.1 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Myosin X N-terminal SH3 domain LBP_BPI_CETP_C PF02886.17 CDJ91913.1 - 9.4e-51 172.6 0.1 1.3e-50 172.0 0.1 1.2 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 CDJ91913.1 - 1.5e-11 44.2 0.6 1.5e-10 40.9 0.0 2.2 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain JHBP PF06585.11 CDJ91913.1 - 0.16 11.1 0.0 8 5.5 0.0 2.2 2 0 0 2 2 2 0 Haemolymph juvenile hormone binding protein (JHBP) LBP_BPI_CETP PF01273.25 CDJ91914.1 - 0.0022 17.6 0.0 0.014 15.1 0.0 2.4 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain DUF4711 PF15829.5 CDJ91915.1 - 0.0015 18.5 0.3 0.0019 18.2 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4711) UbiA PF01040.18 CDJ91915.1 - 0.0032 16.8 0.2 0.0038 16.6 0.2 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family Orf78 PF06024.12 CDJ91915.1 - 0.0055 17.0 0.0 0.0079 16.5 0.0 1.3 1 0 0 1 1 1 1 Orf78 (ac78) DUF1180 PF06679.12 CDJ91915.1 - 0.0061 17.0 0.9 0.0084 16.5 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) DUF1700 PF08006.11 CDJ91915.1 - 0.0075 15.8 3.1 0.0088 15.6 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1700) TMEM154 PF15102.6 CDJ91915.1 - 0.012 15.5 0.1 0.015 15.2 0.1 1.1 1 0 0 1 1 1 0 TMEM154 protein family TRIQK PF15168.6 CDJ91915.1 - 0.017 15.0 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family UL45 PF05473.12 CDJ91915.1 - 0.025 14.2 0.1 0.029 14.0 0.1 1.1 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like DUF5305 PF17231.2 CDJ91915.1 - 0.041 13.3 0.8 0.052 12.9 0.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF5383 PF17355.2 CDJ91915.1 - 0.11 12.9 0.4 0.15 12.4 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5383) DUF4448 PF14610.6 CDJ91915.1 - 0.11 12.3 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF2207 PF09972.9 CDJ91915.1 - 0.12 11.2 0.4 0.14 10.9 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4191 PF13829.6 CDJ91915.1 - 0.16 11.3 1.9 0.18 11.1 1.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Plasmodium_Vir PF05795.11 CDJ91915.1 - 0.16 11.3 0.0 0.18 11.2 0.0 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CrgA PF06781.12 CDJ91915.1 - 0.2 11.7 2.0 2 8.5 0.0 2.1 1 1 1 2 2 2 0 Cell division protein CrgA Pex24p PF06398.11 CDJ91915.1 - 0.2 10.6 2.1 0.25 10.3 2.1 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Insulin_TMD PF17870.1 CDJ91915.1 - 0.24 11.5 3.8 0.47 10.6 3.8 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment SNARE PF05739.19 CDJ91915.1 - 0.62 10.1 6.7 2.5 8.2 6.7 1.9 1 1 0 1 1 1 0 SNARE domain zf-C2HC_2 PF13913.6 CDJ91916.1 - 0.00065 19.5 0.8 0.00065 19.5 0.8 1.8 2 0 0 2 2 2 1 zinc-finger of a C2HC-type Tmemb_55A PF09788.9 CDJ91916.1 - 0.0071 15.5 0.3 0.01 14.9 0.3 1.2 1 0 0 1 1 1 1 Transmembrane protein 55A zf-CpG_bind_C PF12269.8 CDJ91916.1 - 0.12 12.1 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Ion_trans PF00520.31 CDJ91917.1 - 3.3e-10 39.6 8.2 3.3e-10 39.6 8.2 2.4 1 1 0 2 2 2 1 Ion transport protein Ank_4 PF13637.6 CDJ91917.1 - 6.6e-07 29.8 2.5 0.00039 20.9 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ91917.1 - 6.7e-07 29.8 0.4 2.6e-06 27.9 0.3 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ91917.1 - 0.0014 18.8 1.2 0.0049 17.2 0.3 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CDJ91917.1 - 0.0026 18.1 5.4 3.6 8.2 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 CDJ91917.1 - 0.065 13.8 3.7 7.6 7.5 0.1 4.4 4 0 0 4 4 4 0 Ankyrin repeat PKD_channel PF08016.12 CDJ91917.1 - 0.33 9.6 13.4 0.024 13.3 0.6 2.4 2 0 0 2 2 2 0 Polycystin cation channel Destabilase PF05497.12 CDJ91919.1 - 2.3e-18 66.7 10.6 2.6e-18 66.5 10.6 1.0 1 0 0 1 1 1 1 Destabilase zf-RING_2 PF13639.6 CDJ91920.1 - 1.1e-09 38.5 15.7 1.4e-09 38.1 14.0 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ91920.1 - 1.6e-08 34.2 13.1 2.9e-08 33.4 13.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ91920.1 - 3.4e-08 33.2 12.6 3.8e-08 33.1 11.2 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ91920.1 - 1e-06 28.7 10.7 1.9e-06 27.8 10.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 CDJ91920.1 - 4e-06 27.0 11.7 7.9e-06 26.1 11.7 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDJ91920.1 - 6.8e-06 25.9 14.4 6.8e-06 25.9 14.4 1.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ91920.1 - 1.2e-05 25.1 12.4 2e-05 24.4 12.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CDJ91920.1 - 7e-05 22.9 10.7 0.00023 21.3 11.0 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CDJ91920.1 - 0.00057 19.7 11.0 0.001 18.9 11.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CDJ91920.1 - 0.0054 16.7 6.9 0.011 15.8 6.9 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 CDJ91920.1 - 0.018 14.9 6.4 0.026 14.4 6.4 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 CDJ91920.1 - 0.035 13.9 6.5 0.035 13.9 6.5 2.2 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 CDJ91920.1 - 0.11 12.7 8.0 0.18 11.9 8.0 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 DZR PF12773.7 CDJ91920.1 - 0.13 12.4 10.9 1.6 8.8 9.7 2.3 1 1 1 2 2 2 0 Double zinc ribbon DUF1272 PF06906.11 CDJ91920.1 - 0.18 12.0 12.7 1 9.5 10.8 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1272) Zn_ribbon_17 PF17120.5 CDJ91920.1 - 0.82 9.3 11.7 1.9 8.2 11.7 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Pkinase PF00069.25 CDJ91921.1 - 1e-61 208.6 0.0 1.2e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ91921.1 - 4.5e-49 167.1 0.0 6.6e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ91921.1 - 3.9e-05 22.6 0.0 5.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDJ91921.1 - 0.00013 21.4 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDJ91921.1 - 0.051 12.9 0.0 0.091 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDJ91921.1 - 0.16 10.9 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Aldose_epim PF01263.20 CDJ91922.1 - 1.5e-58 198.5 0.0 1.8e-58 198.2 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Branch PF02485.21 CDJ91923.1 - 3.3e-05 23.5 0.0 3.9e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme ABC_membrane PF00664.23 CDJ91924.1 - 8.6e-66 222.4 28.9 8.5e-38 130.6 8.7 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ91924.1 - 7.7e-50 169.0 0.0 3.3e-28 98.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CDJ91924.1 - 3.3e-07 30.0 4.7 0.0097 15.4 0.1 4.1 2 2 1 4 4 4 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CDJ91924.1 - 5.9e-06 26.3 0.6 0.14 12.2 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ91924.1 - 3.3e-05 23.8 0.2 0.0072 16.3 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CDJ91924.1 - 3.6e-05 24.2 0.8 0.16 12.3 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 CDJ91924.1 - 0.00041 20.4 2.7 0.051 13.6 0.4 3.0 3 0 0 3 3 3 1 Dynamin family AAA_25 PF13481.6 CDJ91924.1 - 0.001 18.7 0.0 0.46 10.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CDJ91924.1 - 0.0012 18.5 0.9 2.1 8.1 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 CDJ91924.1 - 0.0021 17.0 0.6 0.01 14.7 0.0 2.0 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 CDJ91924.1 - 0.0055 17.0 0.9 5.4 7.3 0.2 3.5 3 0 0 3 3 3 1 AAA domain MeaB PF03308.16 CDJ91924.1 - 0.015 14.3 0.3 0.5 9.3 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 CDJ91924.1 - 0.04 14.0 2.3 1.1 9.3 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain IstB_IS21 PF01695.17 CDJ91924.1 - 0.081 12.7 0.6 6.3 6.5 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 CDJ91924.1 - 0.09 12.0 0.7 3.2 7.0 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 CDJ91924.1 - 0.15 12.6 0.0 8.5 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 CDJ91924.1 - 0.18 11.6 7.4 11 5.7 0.4 4.3 3 2 0 5 5 5 0 AAA domain, putative AbiEii toxin, Type IV TA system MPS-4 PF17523.2 CDJ91924.1 - 1.5 9.0 5.5 13 5.9 3.4 3.3 2 0 0 2 2 2 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 AAA_5 PF07728.14 CDJ91924.1 - 1.6 8.7 5.2 16 5.5 0.0 4.0 3 1 1 4 4 4 0 AAA domain (dynein-related subfamily) 7tm_1 PF00001.21 CDJ91924.1 - 3.1 7.1 12.9 0.8 9.0 2.1 3.2 3 0 0 3 3 3 0 7 transmembrane receptor (rhodopsin family) RIFIN PF02009.16 CDJ91924.1 - 4.1 7.2 5.3 9 6.1 5.3 1.5 1 0 0 1 1 1 0 Rifin Scs3p PF10261.9 CDJ91925.1 - 7.6e-15 55.1 7.5 4e-14 52.7 7.5 1.8 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.21 CDJ91925.1 - 2.8e-05 23.9 0.9 3.5e-05 23.6 0.9 1.1 1 0 0 1 1 1 1 PAP2 superfamily DUF2116 PF09889.9 CDJ91925.1 - 1 9.4 3.8 1.1 9.2 1.6 2.3 2 1 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Scs3p PF10261.9 CDJ91926.1 - 5.1e-09 36.0 1.0 7.1e-09 35.5 1.0 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM DUF2628 PF10947.8 CDJ91926.1 - 0.67 10.3 5.3 2.3 8.6 5.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2628) Carb_anhydrase PF00194.21 CDJ91927.1 - 2e-64 217.6 0.1 2.5e-64 217.3 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Mtp PF03821.16 CDJ91928.1 - 0.013 15.1 3.5 0.013 15.1 3.5 1.6 1 1 1 2 2 2 0 Golgi 4-transmembrane spanning transporter DUF4728 PF15860.5 CDJ91928.1 - 0.94 10.2 10.8 4.3 8.1 10.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4728) MHYT PF03707.16 CDJ91928.1 - 7.4 6.8 9.8 9 6.5 0.9 3.0 2 1 1 3 3 3 0 Bacterial signalling protein N terminal repeat ApoL PF05461.11 CDJ91929.1 - 6.8e-14 51.9 7.7 9e-14 51.5 7.7 1.1 1 0 0 1 1 1 1 Apolipoprotein L HDV_ag PF01517.18 CDJ91929.1 - 0.033 14.0 0.0 0.72 9.6 0.0 2.1 2 0 0 2 2 2 0 Hepatitis delta virus delta antigen DivIVA PF05103.13 CDJ91929.1 - 0.33 11.1 3.0 0.15 12.1 0.3 1.8 3 0 0 3 3 3 0 DivIVA protein DUF4781 PF16013.5 CDJ91929.1 - 1.4 7.6 6.6 0.54 9.0 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) DNA_pol_A_exo1 PF01612.20 CDJ91930.1 - 4.9e-18 65.5 0.0 9.2e-11 41.8 0.0 2.3 2 0 0 2 2 2 2 3'-5' exonuclease Col_cuticle_N PF01484.17 CDJ91931.1 - 1.1e-18 67.0 0.9 1.6e-18 66.5 0.1 1.7 2 0 0 2 2 2 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ91931.1 - 0.0018 18.0 8.8 0.0024 17.6 8.8 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Glyco_hydro_88 PF07470.13 CDJ91931.1 - 0.018 14.1 0.2 0.024 13.7 0.2 1.0 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 Pkinase PF00069.25 CDJ91932.1 - 1.4e-46 159.0 0.0 1.8e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ91932.1 - 7.1e-20 71.4 0.0 8e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ91932.1 - 0.0012 17.8 0.1 0.0018 17.3 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CDJ91932.1 - 0.0015 18.5 0.0 0.0049 16.8 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDJ91932.1 - 0.026 14.1 0.0 0.099 12.2 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 CDJ91932.1 - 0.09 12.1 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lactamase_B PF00753.27 CDJ91933.1 - 3.4e-15 56.6 9.7 1.3e-13 51.4 9.7 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CDJ91933.1 - 0.24 10.9 3.2 0.41 10.1 3.2 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain AMP-binding PF00501.28 CDJ91934.1 - 6.5e-74 249.0 0.0 8e-74 248.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ91934.1 - 2.1e-10 41.4 0.0 4.1e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_S9 PF00326.21 CDJ91935.1 - 2.9e-52 177.2 0.0 4.2e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 CDJ91935.1 - 1.6e-11 44.2 0.0 3.5e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 CDJ91935.1 - 5.5e-08 32.7 0.7 0.00091 18.9 0.0 2.6 2 1 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 CDJ91935.1 - 1.9e-06 27.3 0.5 0.0009 18.6 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 CDJ91935.1 - 2.9e-05 24.1 0.2 0.0034 17.3 0.2 2.3 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal COesterase PF00135.28 CDJ91935.1 - 0.00013 21.0 0.0 0.00018 20.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDJ91935.1 - 0.00016 21.6 0.2 0.00082 19.3 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2920 PF11144.8 CDJ91935.1 - 0.0011 18.2 0.2 0.83 8.8 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2920) AXE1 PF05448.12 CDJ91935.1 - 0.0045 15.7 0.1 0.021 13.5 0.1 2.0 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 CDJ91935.1 - 0.033 13.9 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Esterase_phd PF10503.9 CDJ91935.1 - 0.034 13.6 1.4 0.068 12.7 1.3 1.6 1 1 0 1 1 1 0 Esterase PHB depolymerase Str_synth PF03088.16 CDJ91935.1 - 0.053 13.6 0.0 0.2 11.8 0.0 2.0 1 0 0 1 1 1 0 Strictosidine synthase DUF829 PF05705.14 CDJ91935.1 - 0.096 12.6 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Aldedh PF00171.22 CDJ91936.1 - 7.6e-135 450.0 0.2 9.2e-135 449.7 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyoxalase_4 PF13669.6 CDJ91937.1 - 1.7e-19 70.1 0.0 2.2e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 CDJ91937.1 - 1.1e-11 45.0 0.0 1.3e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 CDJ91937.1 - 2.1e-09 37.7 0.0 2.6e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain BRX PF08381.11 CDJ91937.1 - 0.031 13.7 0.0 0.074 12.4 0.0 1.6 2 0 0 2 2 2 0 Transcription factor regulating root and shoot growth via Pin3 DUF1338 PF07063.13 CDJ91937.1 - 0.069 12.3 0.0 0.094 11.9 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1338) NolX PF05819.11 CDJ91937.1 - 0.13 11.6 0.2 4 6.7 0.0 2.0 2 0 0 2 2 2 0 NolX protein Nup35_RRM_2 PF14605.6 CDJ91938.1 - 5.5e-09 35.9 0.1 0.0034 17.3 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 CDJ91938.1 - 2.8e-07 30.3 0.0 0.0086 15.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 CDJ91938.1 - 8.6e-07 29.2 0.0 1.7e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.24 CDJ91938.1 - 0.0038 17.1 4.2 0.0065 16.4 4.2 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ91938.1 - 0.034 14.2 2.8 0.058 13.5 2.8 1.4 1 0 0 1 1 1 0 Zinc finger domain Nup35_RRM PF05172.13 CDJ91938.1 - 0.093 12.7 0.2 4.4 7.3 0.0 2.8 2 2 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 CDJ91938.1 - 0.78 10.0 11.5 1.5e+02 2.5 0.0 3.7 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Prominin PF05478.11 CDJ91938.1 - 2.6 5.9 5.1 3.7 5.4 5.1 1.1 1 0 0 1 1 1 0 Prominin DUF4140 PF13600.6 CDJ91938.1 - 2.7 8.5 6.4 3.8 8.0 0.5 2.8 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.11 CDJ91938.1 - 3.9 6.3 12.2 7 5.4 12.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Peptidase_S28 PF05577.12 CDJ91939.1 - 3.5e-94 316.1 0.5 4.3e-94 315.8 0.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 CDJ91939.1 - 0.00045 19.9 0.1 0.00061 19.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S37 PF05576.11 CDJ91939.1 - 0.07 11.8 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 PS-10 peptidase S37 Gp-FAR-1 PF05823.12 CDJ91940.1 - 2.7e-36 125.2 3.3 3.2e-36 124.9 3.3 1.0 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ApoLp-III PF07464.11 CDJ91940.1 - 2.3e-05 24.5 0.2 0.00011 22.3 0.0 1.7 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) DUF3106 PF11304.8 CDJ91940.1 - 2.5e-05 24.7 0.3 0.00023 21.6 0.3 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3106) Tox-ODYAM1 PF15642.6 CDJ91940.1 - 0.03 13.3 0.2 0.049 12.6 0.1 1.3 1 1 0 1 1 1 0 Toxin in Odyssella and Amoebophilus DUF4473 PF14747.6 CDJ91940.1 - 0.034 14.7 0.3 18 6.0 0.0 3.4 1 1 1 3 3 3 0 Domain of unknown function (DUF4473) DUF1043 PF06295.12 CDJ91940.1 - 0.052 13.5 0.8 0.078 13.0 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) eIF3_N PF09440.10 CDJ91940.1 - 0.085 13.3 0.9 7.6 7.0 0.0 2.2 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain Dynamin_M PF01031.20 CDJ91940.1 - 0.09 12.0 0.2 0.17 11.1 0.2 1.5 1 1 0 1 1 1 0 Dynamin central region Metal_resist PF13801.6 CDJ91940.1 - 0.13 12.4 0.0 0.5 10.6 0.0 1.9 1 1 1 2 2 2 0 Heavy-metal resistance Gp-FAR-1 PF05823.12 CDJ91941.1 - 2.4e-35 122.1 1.4 2.9e-35 121.8 1.4 1.0 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ApoLp-III PF07464.11 CDJ91941.1 - 0.0045 17.1 0.0 0.01 15.9 0.0 1.5 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) Dynamin_M PF01031.20 CDJ91941.1 - 0.0066 15.7 0.1 0.01 15.1 0.1 1.4 1 1 0 1 1 1 1 Dynamin central region DUF4473 PF14747.6 CDJ91941.1 - 0.0066 17.0 0.2 0.54 10.8 0.0 3.1 1 1 3 4 4 4 1 Domain of unknown function (DUF4473) Myb_DNA-bind_4 PF13837.6 CDJ91941.1 - 0.009 16.4 0.1 0.019 15.3 0.1 1.7 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Mer2 PF09074.10 CDJ91941.1 - 0.04 13.7 0.1 0.1 12.4 0.1 1.6 1 1 0 1 1 1 0 Mer2 eIF3_N PF09440.10 CDJ91941.1 - 0.11 13.0 0.6 6.1 7.3 0.0 2.2 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain HEAT PF02985.22 CDJ91942.1 - 0.0018 18.4 8.2 1.7 9.1 0.0 4.4 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 CDJ91942.1 - 0.0043 17.4 0.6 0.027 14.8 0.1 2.5 2 0 0 2 2 2 1 HEAT repeats Cnd1 PF12717.7 CDJ91942.1 - 0.0062 16.6 1.6 0.16 12.0 0.3 3.3 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 DUF913 PF06025.12 CDJ91942.1 - 0.19 10.7 0.8 0.36 9.8 0.0 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) FAM176 PF14851.6 CDJ91942.1 - 0.57 9.8 8.2 8.1 6.1 0.1 2.6 2 0 0 2 2 2 0 FAM176 family RPN2_C PF18004.1 CDJ91942.1 - 2.5 8.0 11.9 1.3 8.9 0.4 2.3 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain EMG1 PF03587.14 CDJ91943.1 - 0.029 14.0 0.4 0.08 12.6 0.1 1.8 2 0 0 2 2 2 0 EMG1/NEP1 methyltransferase BRF1 PF07741.13 CDJ91944.1 - 1.6 9.1 12.1 2.1 8.7 12.1 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Neur_chan_memb PF02932.16 CDJ91944.1 - 2.3 8.2 4.4 2.4 8.2 4.4 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Laminin_EGF PF00053.24 CDJ91945.1 - 0.00037 20.6 36.0 1 9.6 15.2 4.4 1 1 3 4 4 4 4 Laminin EGF domain hEGF PF12661.7 CDJ91945.1 - 0.1 13.3 1.9 0.1 13.3 1.9 5.1 5 0 0 5 5 5 0 Human growth factor-like EGF EGF PF00008.27 CDJ91945.1 - 0.18 12.1 0.2 0.18 12.1 0.2 5.3 5 3 0 5 5 5 0 EGF-like domain RT_RNaseH_2 PF17919.1 CDJ91946.1 - 1.2e-35 121.5 0.1 3.5e-35 120.0 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ91946.1 - 7.7e-33 112.9 0.0 2.1e-32 111.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ91946.1 - 5.6e-23 81.4 0.0 1.9e-22 79.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ91946.1 - 3.8e-19 68.5 0.2 1.4e-18 66.7 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 CDJ91946.1 - 6e-10 39.0 0.0 1.2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 CDJ91946.1 - 6.1e-05 22.7 0.0 0.00017 21.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CDJ91946.1 - 6.5e-05 23.1 0.1 0.00016 21.8 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF2018 PF09442.10 CDJ91946.1 - 0.086 13.8 0.0 4.2 8.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) Astacin PF01400.24 CDJ91947.1 - 0.00098 18.8 2.0 0.0011 18.7 0.7 1.6 1 1 1 2 2 2 1 Astacin (Peptidase family M12A) CUB PF00431.20 CDJ91947.1 - 0.016 15.5 0.0 0.035 14.4 0.0 1.6 1 0 0 1 1 1 0 CUB domain BRCT_2 PF16589.5 CDJ91948.1 - 3.8e-10 40.0 0.0 7.6e-08 32.7 0.0 2.6 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain zf-RING_UBOX PF13445.6 CDJ91948.1 - 6.2e-09 35.7 8.6 2.1e-08 34.0 8.6 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDJ91948.1 - 8.2e-09 35.2 9.5 2.8e-08 33.5 9.5 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ91948.1 - 1.5e-08 34.3 10.0 6.5e-08 32.3 10.0 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ91948.1 - 5e-08 33.2 10.9 2.2e-07 31.1 10.9 2.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ91948.1 - 1.6e-07 31.0 10.4 1.6e-07 31.0 10.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 CDJ91948.1 - 4.6e-06 26.3 5.3 1e-05 25.2 5.3 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 CDJ91948.1 - 6e-06 26.3 11.1 6e-06 26.3 11.1 2.5 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CDJ91948.1 - 2.5e-05 24.0 13.5 0.00011 22.0 13.5 2.1 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CDJ91948.1 - 4.5e-05 23.3 11.4 4.5e-05 23.3 11.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain BRCT PF00533.26 CDJ91948.1 - 0.0006 20.1 0.0 0.24 11.8 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain zf-rbx1 PF12678.7 CDJ91948.1 - 0.031 14.6 7.7 0.17 12.2 7.7 2.3 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 CDJ91948.1 - 0.045 13.6 7.0 0.13 12.2 7.0 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 CDJ91948.1 - 9.7 6.4 14.5 1.6 8.9 9.5 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 Exo_endo_phos_2 PF14529.6 CDJ91950.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Pkinase PF00069.25 CDJ91951.1 - 3.9e-24 85.4 0.3 4.5e-24 85.2 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ91951.1 - 4.1e-14 52.5 0.0 4.7e-14 52.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ91951.1 - 7e-06 26.1 0.0 0.0012 18.8 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ91951.1 - 3.3e-05 22.8 0.0 4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 CDJ91951.1 - 0.081 12.5 0.1 6.5 6.3 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Dicer_dimer PF03368.14 CDJ91951.1 - 0.16 12.1 0.1 0.28 11.4 0.1 1.7 1 1 0 1 1 1 0 Dicer dimerisation domain HA2 PF04408.23 CDJ91952.1 - 1.9e-16 60.2 0.1 4.6e-16 59.0 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CDJ91952.1 - 1.3e-12 48.1 0.0 5.2e-12 46.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CDJ91952.1 - 3.5e-12 46.5 0.0 8.1e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CDJ91952.1 - 1.1e-05 25.2 0.0 2.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CDJ91952.1 - 0.006 16.9 0.0 0.017 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CDJ91952.1 - 0.007 16.9 0.1 0.034 14.6 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 CDJ91952.1 - 0.0073 16.6 1.6 0.022 15.0 0.6 2.3 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CDJ91952.1 - 0.01 15.4 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 CDJ91952.1 - 0.032 13.8 0.0 0.53 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CDJ91952.1 - 0.063 13.2 0.1 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase Helicase_RecD PF05127.14 CDJ91952.1 - 0.074 12.9 0.0 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 Helicase NACHT PF05729.12 CDJ91952.1 - 0.085 12.8 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 NACHT domain I-set PF07679.16 CDJ91954.1 - 4.5e-63 209.3 0.0 3.7e-15 55.7 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ91954.1 - 1.9e-39 134.1 0.0 4.6e-08 33.5 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 CDJ91954.1 - 2e-22 79.3 0.0 4.8e-05 23.6 0.0 4.7 4 1 1 5 5 5 4 Immunoglobulin domain ig PF00047.25 CDJ91954.1 - 6.9e-21 74.2 0.0 4.4e-06 26.8 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin domain fn3 PF00041.21 CDJ91954.1 - 4.3e-09 36.6 0.0 1.1e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain C2-set_2 PF08205.12 CDJ91954.1 - 3e-06 27.2 0.1 1.3 9.2 0.0 4.3 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 CDJ91954.1 - 1.4e-05 25.2 0.0 0.041 14.0 0.0 4.3 4 1 0 4 4 4 1 Immunoglobulin V-set domain Ig_6 PF18452.1 CDJ91954.1 - 0.00093 18.7 0.0 0.48 10.0 0.1 3.5 3 0 0 3 3 3 1 Immunoglobulin domain C1-set PF07654.15 CDJ91954.1 - 0.0036 17.7 0.0 0.7 10.3 0.0 3.2 3 0 0 3 3 3 1 Immunoglobulin C1-set domain Ig_4 PF16680.5 CDJ91954.1 - 0.042 14.1 0.1 1.5 9.1 0.0 3.0 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 CDJ91954.1 - 0.1 13.0 0.0 4.6 7.7 0.0 3.4 4 0 0 4 4 4 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain PhoLip_ATPase_C PF16212.5 CDJ91955.1 - 8.9e-71 238.6 27.7 8.9e-71 238.6 27.7 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CDJ91955.1 - 9.9e-21 73.2 0.4 9.9e-21 73.2 0.4 3.7 4 0 0 4 4 4 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CDJ91955.1 - 1.4e-11 45.1 0.0 1.8e-05 25.2 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDJ91955.1 - 1.4e-09 37.9 0.0 6.7e-09 35.7 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CDJ91955.1 - 1.1e-06 28.3 1.5 2.4e-06 27.2 0.0 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CDJ91955.1 - 0.0024 17.7 0.1 0.0064 16.3 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase OFeT_1 PF16955.5 CDJ91955.1 - 0.039 13.7 0.8 0.08 12.6 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron uptake permease, iron-lead transporter Astacin PF01400.24 CDJ91956.1 - 6.5e-22 78.1 0.1 9.7e-22 77.5 0.1 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB PF00431.20 CDJ91956.1 - 0.011 16.0 0.1 0.018 15.4 0.1 1.4 1 0 0 1 1 1 0 CUB domain NPP1 PF05630.11 CDJ91956.1 - 0.034 14.3 0.1 0.068 13.3 0.1 1.5 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) EGF_2 PF07974.13 CDJ91956.1 - 0.78 10.2 11.7 2.1 8.8 11.7 1.8 1 1 0 1 1 1 0 EGF-like domain Cytokin-bind PF09265.10 CDJ91958.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 1 1 1 2 2 2 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding TPP_enzyme_M_2 PF16582.5 CDJ91958.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Middle domain of thiamine pyrophosphate BK_channel_a PF03493.18 CDJ91959.1 - 1.2e-26 92.7 0.2 2.1e-25 88.7 0.1 2.6 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 CDJ91959.1 - 9.5e-14 51.1 3.4 2.6e-13 49.7 3.4 1.7 1 0 0 1 1 1 1 Ion channel TrkA_C PF02080.21 CDJ91959.1 - 4e-05 23.4 0.0 0.057 13.3 0.0 3.3 3 0 0 3 3 3 1 TrkA-C domain TrkA_N PF02254.18 CDJ91959.1 - 0.012 15.9 0.1 2.5 8.4 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain Lig_chan PF00060.26 CDJ91959.1 - 0.012 15.4 1.9 0.031 14.1 1.9 1.7 1 1 0 1 1 1 0 Ligand-gated ion channel DUF3437 PF11919.8 CDJ91960.1 - 8.3e-20 70.5 0.0 2e-19 69.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) Cnd1 PF12717.7 CDJ91960.1 - 0.00045 20.3 1.4 0.0011 19.0 0.3 2.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDJ91960.1 - 0.00047 20.5 0.0 0.37 11.2 0.0 2.4 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 CDJ91960.1 - 0.027 14.7 3.1 0.94 9.9 0.2 3.6 3 0 0 3 3 3 0 HEAT repeat Collagen PF01391.18 CDJ91961.1 - 6e-08 32.3 15.2 1.1e-07 31.5 15.2 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Tropomodulin PF03250.14 CDJ91962.1 - 2e-50 170.5 2.0 2e-50 170.5 2.0 2.2 2 0 0 2 2 2 1 Tropomodulin HSP90 PF00183.18 CDJ91963.1 - 3.1e-218 725.9 22.4 4.7e-218 725.3 22.4 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CDJ91963.1 - 1.6e-11 44.7 0.1 3e-11 43.8 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CDJ91963.1 - 1.9e-09 37.5 0.1 1.9e-09 37.5 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EFhand_Ca_insen PF08726.10 CDJ91963.1 - 0.066 13.3 0.0 1.8 8.7 0.0 2.9 2 0 0 2 2 2 0 Ca2+ insensitive EF hand PAS_12 PF18095.1 CDJ91963.1 - 0.07 12.8 1.6 0.12 12.0 0.5 2.0 2 0 0 2 2 2 0 UPF0242 C-terminal PAS-like domain Flt3_lig PF02947.14 CDJ91963.1 - 0.16 12.1 0.2 0.5 10.5 0.2 1.8 1 1 0 1 1 1 0 flt3 ligand STPPase_N PF16891.5 CDJ91966.1 - 3.5e-24 85.0 1.0 5.8e-24 84.3 1.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 CDJ91966.1 - 1.8e-10 41.7 0.0 2.4e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase P22_AR_C PF10548.9 CDJ91966.1 - 0.16 12.1 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 P22AR C-terminal domain BCAS3 PF12490.8 CDJ91967.1 - 4.6e-10 39.4 2.1 6.7e-05 22.5 0.0 2.6 2 1 1 3 3 3 2 Breast carcinoma amplified sequence 3 WD40 PF00400.32 CDJ91967.1 - 0.072 14.0 0.7 3.2 8.8 0.0 3.0 2 0 0 2 2 2 0 WD domain, G-beta repeat ShK PF01549.24 CDJ91968.1 - 2.4e-05 24.8 3.5 3.3e-05 24.3 3.5 1.2 1 0 0 1 1 1 1 ShK domain-like PTN_MK_N PF05196.13 CDJ91968.1 - 0.047 13.9 3.5 0.075 13.3 3.5 1.3 1 0 0 1 1 1 0 PTN/MK heparin-binding protein family, N-terminal domain BTB PF00651.31 CDJ91969.1 - 9.7e-09 35.4 0.0 1.7e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BAR PF03114.18 CDJ91969.1 - 0.11 12.1 0.1 0.15 11.6 0.1 1.1 1 0 0 1 1 1 0 BAR domain Tim44 PF04280.15 CDJ91970.1 - 1.9e-20 73.5 0.0 3.5e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.11 CDJ91970.1 - 0.0024 17.0 0.0 0.004 16.2 0.0 1.4 1 0 0 1 1 1 1 MBA1-like protein DSS1_SEM1 PF05160.13 CDJ91971.1 - 1.3e-17 63.6 19.4 1.6e-17 63.3 19.4 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family MFS_1 PF07690.16 CDJ91972.1 - 5.3e-48 163.7 47.7 1.3e-43 149.3 34.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HMG_box PF00505.19 CDJ91973.1 - 0.024 15.0 0.7 0.06 13.8 0.7 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ91973.1 - 0.028 15.0 1.8 0.081 13.5 1.8 1.8 1 0 0 1 1 1 0 HMG-box domain DUF747 PF05346.11 CDJ91974.1 - 8.6e-106 354.0 18.3 1.1e-105 353.6 18.3 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family RhoGAP PF00620.27 CDJ91975.1 - 3.7e-35 121.0 0.0 6.2e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Ribosomal_S9 PF00380.19 CDJ91976.1 - 3.9e-26 92.0 0.1 7.2e-26 91.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 MEIOC PF15189.6 CDJ91977.1 - 8e-63 211.0 2.3 1.3e-62 210.3 2.3 1.3 1 0 0 1 1 1 1 Meiosis-specific coiled-coil domain-containing protein MEIOC ALIX_LYPXL_bnd PF13949.6 CDJ91977.1 - 0.0058 16.0 4.6 0.054 12.8 1.5 2.1 2 0 0 2 2 2 2 ALIX V-shaped domain binding to HIV DnaG_DnaB_bind PF08278.11 CDJ91977.1 - 0.042 14.4 1.4 0.042 14.4 1.4 2.3 2 1 0 2 2 2 0 DNA primase DnaG DnaB-binding DivIVA PF05103.13 CDJ91977.1 - 1.8 8.7 4.6 0.74 9.9 0.9 2.0 2 0 0 2 2 2 0 DivIVA protein MtN3_slv PF03083.16 CDJ91978.1 - 3e-48 161.8 10.2 9.1e-25 86.5 3.3 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Oxidored_q2 PF00420.24 CDJ91978.1 - 0.055 13.1 4.0 0.091 12.4 1.5 2.6 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L LAB_N PF07578.11 CDJ91978.1 - 0.1 12.7 2.6 3 8.0 0.4 2.7 2 0 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain HSP9_HSP12 PF04119.12 CDJ91980.1 - 0.45 10.9 2.9 5.7 7.4 0.1 2.5 2 0 0 2 2 2 0 Heat shock protein 9/12 DUF3993 PF13158.6 CDJ91981.1 - 0.02 15.1 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) HHH_5 PF14520.6 CDJ91981.1 - 0.046 14.3 0.3 0.088 13.4 0.1 1.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain HSP9_HSP12 PF04119.12 CDJ91981.1 - 0.23 11.9 3.7 4.3 7.8 0.2 2.6 2 1 0 2 2 2 0 Heat shock protein 9/12 HSP9_HSP12 PF04119.12 CDJ91982.1 - 0.21 12.0 1.8 3.8 8.0 0.1 2.5 2 1 0 2 2 2 0 Heat shock protein 9/12 HofP PF10748.9 CDJ91983.1 - 0.083 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 DNA utilization proteins HofP Ank_2 PF12796.7 CDJ91984.1 - 7.8e-37 125.7 14.7 8.1e-12 45.6 0.2 6.0 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ91984.1 - 1e-29 102.5 10.4 3.2e-07 30.8 0.7 8.7 4 3 3 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ91984.1 - 2.1e-17 62.9 8.6 1.6e-08 34.6 0.2 7.7 3 3 6 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ91984.1 - 4.7e-15 54.2 15.9 0.022 15.3 0.1 10.9 12 0 0 12 12 11 3 Ankyrin repeat Ank PF00023.30 CDJ91984.1 - 4.8e-10 39.4 14.2 0.0088 16.5 0.1 9.3 10 0 0 10 10 10 2 Ankyrin repeat TPR_2 PF07719.17 CDJ91984.1 - 0.00019 21.3 1.1 0.032 14.3 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ91984.1 - 0.00075 19.7 1.7 0.0056 16.9 0.4 2.9 3 0 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CDJ91984.1 - 0.004 17.9 0.1 3.1 8.8 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ91984.1 - 0.0052 16.6 0.1 0.18 11.7 0.0 3.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ91984.1 - 0.0058 16.9 0.4 5.3 7.4 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat NACHT PF05729.12 CDJ91984.1 - 0.0064 16.4 0.1 0.2 11.5 0.1 2.9 3 0 0 3 3 3 1 NACHT domain TPR_8 PF13181.6 CDJ91984.1 - 0.012 15.7 0.0 0.21 11.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ91984.1 - 0.024 15.3 0.1 1.5 9.5 0.0 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat AAA_16 PF13191.6 CDJ91984.1 - 0.046 14.1 0.0 0.5 10.7 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 CDJ91984.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TPR_7 PF13176.6 CDJ91984.1 - 0.065 13.3 0.1 4.6 7.5 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ91984.1 - 0.075 13.7 0.0 46 4.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat CAP_GLY PF01302.25 CDJ91985.1 - 2.7e-49 165.0 2.0 1.7e-24 85.6 0.5 2.4 2 0 0 2 2 2 2 CAP-Gly domain CLIP1_ZNF PF16641.5 CDJ91985.1 - 9.8e-13 47.6 20.7 7.9e-08 32.0 5.7 2.4 2 0 0 2 2 2 2 CLIP1 zinc knuckle DDE_Tnp_IS1595 PF12762.7 CDJ91986.1 - 2.7e-06 27.4 0.0 4.8e-06 26.7 0.0 1.3 1 1 0 1 1 1 1 ISXO2-like transposase domain YdaS_antitoxin PF15943.5 CDJ91986.1 - 0.032 14.1 0.1 0.26 11.2 0.1 2.1 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DnaA_N PF11638.8 CDJ91986.1 - 0.063 13.0 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 DnaA N-terminal domain DUF4286 PF14114.6 CDJ91986.1 - 0.084 13.4 0.1 0.14 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) DUF746 PF05344.11 CDJ91986.1 - 0.087 12.7 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) Myosin_tail_1 PF01576.19 CDJ91988.1 - 1.2e-05 23.4 78.7 2.5e-05 22.3 78.6 1.3 1 1 0 1 1 1 1 Myosin tail AAA_13 PF13166.6 CDJ91988.1 - 0.0066 15.2 55.8 0.017 13.8 39.4 3.7 1 1 3 4 4 4 2 AAA domain TMF_DNA_bd PF12329.8 CDJ91988.1 - 0.022 14.8 14.8 0.022 14.8 14.8 7.7 3 2 3 8 8 8 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.12 CDJ91988.1 - 0.5 10.4 78.6 0.51 10.4 12.9 5.3 2 2 2 4 4 4 0 TPR/MLP1/MLP2-like protein Bacillus_HBL PF05791.11 CDJ91988.1 - 0.94 9.3 32.6 1.6 8.6 3.3 4.9 1 1 3 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) DUF2353 PF09789.9 CDJ91988.1 - 1.6 8.0 61.6 0.5 9.7 31.7 2.8 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Golgin_A5 PF09787.9 CDJ91988.1 - 2.8 7.3 74.3 0.16 11.4 20.2 3.9 1 1 3 4 4 4 0 Golgin subfamily A member 5 DUF5082 PF16888.5 CDJ91988.1 - 3.7 7.8 40.9 11 6.3 0.0 5.0 2 1 3 5 5 5 0 Domain of unknown function (DUF5082) Spc7 PF08317.11 CDJ91988.1 - 5.2 5.9 75.2 1.8 7.3 23.5 4.1 1 1 3 4 4 4 0 Spc7 kinetochore protein DUF948 PF06103.11 CDJ91988.1 - 8.9 6.6 25.3 0.63 10.3 1.5 5.3 1 1 4 6 6 6 0 Bacterial protein of unknown function (DUF948) DDE_3 PF13358.6 CDJ91989.1 - 0.0028 17.4 0.0 0.0042 16.9 0.0 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.27 CDJ91990.1 - 2.9e-05 23.7 0.0 6.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Gal-bind_lectin PF00337.22 CDJ91991.1 - 2e-24 85.7 0.9 2.6e-24 85.3 0.9 1.1 1 0 0 1 1 1 1 Galactoside-binding lectin Gal-bind_lectin PF00337.22 CDJ91992.1 - 5e-23 81.1 0.6 6e-23 80.9 0.6 1.1 1 0 0 1 1 1 1 Galactoside-binding lectin DpaA_N PF16924.5 CDJ91992.1 - 0.17 12.0 0.0 0.54 10.4 0.0 1.7 1 1 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain Bromo_TP PF07524.13 CDJ91993.1 - 4.4e-09 36.2 0.0 7.2e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated PHD PF00628.29 CDJ91993.1 - 1.8e-07 30.9 15.0 6.1e-07 29.2 14.6 2.1 1 1 1 2 2 2 1 PHD-finger TFIID-31kDa PF02291.15 CDJ91993.1 - 0.00021 21.3 0.0 0.00076 19.6 0.0 1.9 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 CDJ91993.1 - 0.007 16.7 0.0 0.007 16.7 0.0 6.9 5 1 0 5 5 5 1 Core histone H2A/H2B/H3/H4 Bromo_TP_like PF17027.5 CDJ91993.1 - 0.0098 16.0 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 1 Histone-fold protein PHD_2 PF13831.6 CDJ91993.1 - 0.051 13.1 11.4 0.02 14.5 6.7 2.2 2 0 0 2 2 2 0 PHD-finger CENP-S PF15630.6 CDJ91993.1 - 0.056 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 CENP-S protein Forkhead PF00250.18 CDJ91994.1 - 1.2e-28 99.2 0.3 2.2e-28 98.3 0.3 1.4 1 0 0 1 1 1 1 Forkhead domain zf-TAZ PF02135.16 CDJ91995.1 - 3.1e-05 24.3 6.4 7.6e-05 23.1 6.4 1.7 1 0 0 1 1 1 1 TAZ zinc finger Glyco_hydro_25 PF01183.20 CDJ91997.1 - 1.1e-12 48.5 5.1 1.4e-12 48.2 5.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 DUF1906 PF08924.11 CDJ91997.1 - 0.055 13.6 6.3 0.09 12.9 6.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1906) TSC22 PF01166.18 CDJ91999.1 - 1.8e-22 79.4 0.4 3.4e-22 78.5 0.4 1.5 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF5415 PF17436.2 CDJ91999.1 - 0.01 15.9 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5415) SOGA PF11365.8 CDJ91999.1 - 0.019 16.1 0.1 0.043 14.9 0.1 1.6 1 0 0 1 1 1 0 Protein SOGA TSP_1 PF00090.19 CDJ92000.1 - 3e-33 113.8 68.5 5.5e-10 39.3 7.3 6.1 6 0 0 6 6 6 6 Thrombospondin type 1 domain DUF547 PF04784.14 CDJ92001.1 - 3.4e-27 94.9 0.0 4.3e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF547 GRAM PF02893.20 CDJ92002.1 - 4.5e-19 68.4 0.7 8.2e-19 67.6 0.7 1.4 1 0 0 1 1 1 1 GRAM domain Apolipoprotein PF01442.18 CDJ92003.1 - 0.0026 17.7 7.1 0.0056 16.6 7.1 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain CCDC53 PF10152.9 CDJ92003.1 - 0.011 16.1 2.3 0.011 16.1 2.3 3.4 2 1 0 2 2 1 0 Subunit CCDC53 of WASH complex SesA PF17107.5 CDJ92003.1 - 0.025 14.8 3.8 0.057 13.6 3.4 1.8 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Cob_adeno_trans PF01923.18 CDJ92003.1 - 0.22 11.7 2.6 0.36 11.0 0.7 2.1 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Peptidase_M16_C PF05193.21 CDJ92003.1 - 0.36 10.8 1.3 0.67 9.9 0.2 2.1 2 0 0 2 2 2 0 Peptidase M16 inactive domain FH2 PF02181.23 CDJ92003.1 - 0.37 9.9 9.7 2.5 7.1 2.3 2.4 1 1 1 2 2 2 0 Formin Homology 2 Domain Exonuc_VII_L PF02601.15 CDJ92003.1 - 0.46 10.0 6.9 1.1 8.8 6.9 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_M32 PF02074.15 CDJ92003.1 - 0.5 9.1 3.3 0.84 8.3 3.3 1.2 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase DUF1759 PF03564.15 CDJ92003.1 - 0.61 10.0 2.2 1.7 8.6 0.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1759) Fez1 PF06818.15 CDJ92003.1 - 0.95 9.9 12.3 0.2 12.1 6.3 2.4 1 1 1 2 2 2 0 Fez1 Uso1_p115_C PF04871.13 CDJ92003.1 - 1 9.7 11.9 0.38 11.1 3.0 2.8 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region NPV_P10 PF05531.12 CDJ92003.1 - 1.3 9.5 4.9 7.2 7.1 0.5 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.11 CDJ92003.1 - 1.5 9.4 6.2 9.3 6.9 5.8 2.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal FUSC PF04632.12 CDJ92003.1 - 2 6.9 2.7 3 6.3 2.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Prefoldin_2 PF01920.20 CDJ92003.1 - 2 8.4 10.1 0.36 10.8 0.2 2.9 3 0 0 3 3 3 0 Prefoldin subunit Cbl_N PF02262.16 CDJ92003.1 - 2.3 8.2 4.8 28 4.7 1.1 2.3 1 1 1 2 2 2 0 CBL proto-oncogene N-terminal domain 1 LMBR1 PF04791.16 CDJ92003.1 - 2.7 6.8 5.7 3.9 6.3 5.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1664 PF07889.12 CDJ92003.1 - 2.7 8.0 7.5 35 4.5 7.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 CDJ92003.1 - 2.8 7.2 7.8 5.1 6.4 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2868 PF11067.8 CDJ92003.1 - 3.8 6.9 5.7 0.99 8.9 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) Spc7 PF08317.11 CDJ92003.1 - 4.4 6.1 12.4 10 4.9 12.4 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein PIN_8 PF18476.1 CDJ92003.1 - 5.7 6.7 7.2 0.76 9.6 1.7 2.1 1 1 1 2 2 2 0 PIN like domain Baculo_PEP_C PF04513.12 CDJ92003.1 - 5.9 6.9 9.6 42 4.2 7.9 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NeA_P2 PF12312.8 CDJ92003.1 - 7.7 5.9 10.4 0.071 12.6 0.7 2.4 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein RVT_1 PF00078.27 CDJ92004.1 - 6.2e-15 55.3 0.0 1.1e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_4 PF12799.7 CDJ92005.1 - 3.6e-19 68.5 4.5 4.1e-07 30.2 0.5 5.4 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ92005.1 - 1.3e-15 56.9 8.9 2.3e-07 30.4 0.2 3.4 3 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 CDJ92005.1 - 6.6e-13 47.6 5.8 0.022 14.8 0.5 6.8 6 0 0 6 6 6 5 Leucine Rich repeat LRR_9 PF14580.6 CDJ92005.1 - 4.3e-10 39.4 1.8 5e-07 29.4 0.1 2.8 1 1 2 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 CDJ92005.1 - 0.031 14.8 13.3 38 5.4 0.0 6.7 7 0 0 7 7 7 0 Leucine Rich Repeat RecQ_Zn_bind PF16124.5 CDJ92005.1 - 1 10.2 2.8 5.3 7.9 1.2 2.8 3 0 0 3 3 3 0 RecQ zinc-binding G3P_acyltransf PF02660.15 CDJ92006.1 - 0.083 13.0 7.8 0.12 12.4 7.8 1.3 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase CARM1 PF11531.8 CDJ92006.1 - 0.1 12.8 1.7 0.14 12.3 0.7 1.8 1 1 1 2 2 2 0 Coactivator-associated arginine methyltransferase 1 N terminal zf-AN1 PF01428.16 CDJ92007.1 - 1.6e-22 79.3 29.9 9.3e-12 44.9 12.9 2.9 3 0 0 3 3 3 2 AN1-like Zinc finger UIM PF02809.20 CDJ92007.1 - 0.0059 16.5 4.2 0.015 15.2 4.2 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif Transp_Tc5_C PF04236.15 CDJ92007.1 - 0.1 12.9 19.7 0.7 10.3 8.0 2.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zf-C3HC PF07967.13 CDJ92007.1 - 2.7 8.0 8.4 3.2 7.8 3.0 2.3 2 0 0 2 2 2 0 C3HC zinc finger-like IBR PF01485.21 CDJ92007.1 - 4.7 7.5 25.6 9.8 6.5 16.4 3.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain DEAD PF00270.29 CDJ92008.1 - 1.6e-48 164.7 0.0 3.1e-48 163.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ92008.1 - 5.9e-29 100.6 0.0 2.9e-28 98.4 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ92008.1 - 0.00048 20.2 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Keratin_2_head PF16208.5 CDJ92008.1 - 0.0026 17.9 22.3 0.0026 17.9 22.3 2.3 2 0 0 2 2 2 1 Keratin type II head UTP25 PF06862.12 CDJ92008.1 - 0.18 10.5 0.0 5.7 5.6 0.0 2.3 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 RAD51_interact PF15696.5 CDJ92008.1 - 0.19 11.9 0.6 0.44 10.7 0.6 1.6 1 0 0 1 1 1 0 RAD51 interacting motif Lipid_DES PF08557.10 CDJ92009.1 - 2.3e-19 68.6 0.1 4.1e-19 67.8 0.1 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) FA_desaturase PF00487.24 CDJ92009.1 - 3.7e-18 66.3 12.8 5.9e-18 65.6 12.8 1.3 1 0 0 1 1 1 1 Fatty acid desaturase AA_permease_C PF13906.6 CDJ92009.1 - 0.83 9.8 4.0 0.51 10.5 0.6 2.3 2 0 0 2 2 2 0 C-terminus of AA_permease CAP_N PF01213.19 CDJ92010.1 - 0.26 10.8 1.5 0.34 10.3 1.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal LRR_8 PF13855.6 CDJ92011.1 - 1.6e-20 72.6 12.2 4.7e-06 26.3 0.0 4.4 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CDJ92011.1 - 3.5e-15 55.9 13.3 3.6e-05 24.0 1.9 4.1 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CDJ92011.1 - 1.6e-06 27.7 10.9 9 6.6 0.0 6.5 6 0 0 6 6 6 4 Leucine Rich repeat LRR_5 PF13306.6 CDJ92011.1 - 0.00048 20.1 0.0 0.12 12.4 0.0 2.2 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 CDJ92011.1 - 0.0012 19.1 9.1 13 6.8 0.4 6.0 3 3 0 3 3 3 1 Leucine Rich Repeat SNF PF00209.18 CDJ92012.1 - 4e-67 227.1 19.2 5.4e-67 226.7 19.2 1.2 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Tetraspanin PF00335.20 CDJ92013.1 - 9.2e-17 61.5 12.4 1.2e-16 61.2 12.4 1.1 1 0 0 1 1 1 1 Tetraspanin family Cmc1 PF08583.10 CDJ92013.1 - 9.1e-07 28.8 0.3 1.8e-06 27.9 0.3 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF2250 PF10007.9 CDJ92013.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) YfhO PF09586.10 CDJ92013.1 - 0.27 9.4 2.6 0.36 9.0 2.6 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO L6_membrane PF05805.12 CDJ92013.1 - 0.34 10.5 8.7 0.097 12.2 5.6 1.6 2 0 0 2 2 2 0 L6 membrane protein DUF3810 PF12725.7 CDJ92013.1 - 0.4 10.0 1.7 0.49 9.7 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) ABC1 PF03109.16 CDJ92014.1 - 4.3e-34 117.2 0.0 7.4e-34 116.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family PAN_1 PF00024.26 CDJ92015.1 - 2.8e-07 30.4 0.6 3.8e-07 30.0 0.6 1.2 1 0 0 1 1 1 1 PAN domain Y_phosphatase PF00102.27 CDJ92016.1 - 6.3e-06 25.9 0.0 2.1e-05 24.2 0.0 1.6 1 1 1 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ92016.1 - 2.8e-05 24.0 0.0 4.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDJ92016.1 - 0.12 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family zf-C4 PF00105.18 CDJ92017.1 - 6.5e-24 84.2 14.6 1.2e-23 83.3 14.6 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ92017.1 - 2.6e-17 63.1 0.1 6.4e-17 61.8 0.1 1.6 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor EspF PF04806.12 CDJ92017.1 - 0.028 14.8 1.3 0.056 13.9 1.3 1.4 1 0 0 1 1 1 0 EspF protein repeat zf-C4 PF00105.18 CDJ92018.1 - 1.1e-22 80.3 15.4 2e-22 79.4 15.4 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) zf-RRPl_C4 PF17026.5 CDJ92018.1 - 0.00073 19.6 7.6 0.0039 17.3 8.1 1.8 2 0 0 2 2 2 1 Putative ribonucleoprotein zinc-finger pf C4 type DUF2318 PF10080.9 CDJ92018.1 - 0.0012 18.9 0.9 0.0028 17.8 0.9 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) Hormone_recep PF00104.30 CDJ92018.1 - 0.086 12.4 0.7 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 Ligand-binding domain of nuclear hormone receptor MCM_bind PF09739.9 CDJ92018.1 - 0.38 9.2 4.7 0.55 8.6 4.7 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor BRO1 PF03097.18 CDJ92019.1 - 1.4e-28 99.8 0.0 1.9e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain DUF3844 PF12955.7 CDJ92020.1 - 0.15 12.2 2.6 0.34 11.0 2.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3844) DUF4649 PF15507.6 CDJ92021.1 - 0.11 12.5 0.0 0.42 10.6 0.0 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4649) Clathrin_lg_ch PF01086.17 CDJ92022.1 - 0.0046 17.0 0.0 0.0046 17.0 0.0 1.0 1 0 0 1 1 1 1 Clathrin light chain Pkinase PF00069.25 CDJ92024.1 - 5.8e-17 61.9 0.0 1.6e-16 60.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ92024.1 - 2.7e-06 26.9 0.0 7.7e-06 25.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase tRNA-synt_2b PF00587.25 CDJ92025.1 - 2.1e-30 106.0 0.0 3.9e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Acetyltransf_1 PF00583.25 CDJ92026.1 - 1.9e-05 24.8 0.0 3.5e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDJ92026.1 - 0.045 13.7 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CDJ92026.1 - 0.048 13.7 0.0 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 CDJ92026.1 - 0.055 13.6 0.0 2.7 8.1 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDJ92026.1 - 0.16 12.4 0.0 0.34 11.4 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Lustrin_cystein PF14625.6 CDJ92027.1 - 4.7 7.7 17.1 42 4.6 15.0 2.9 2 1 0 2 2 2 0 Lustrin, cysteine-rich repeated domain Bestrophin PF01062.21 CDJ92028.1 - 1.5e-90 303.5 7.6 1.9e-90 303.2 7.6 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PDZ PF00595.24 CDJ92029.1 - 8.4e-68 224.7 12.0 1.8e-17 63.4 0.0 5.3 5 0 0 5 5 5 5 PDZ domain PDZ_6 PF17820.1 CDJ92029.1 - 2.2e-47 158.7 22.6 5.8e-11 42.1 1.4 5.3 5 0 0 5 5 5 5 PDZ domain PDZ_2 PF13180.6 CDJ92029.1 - 1.7e-27 95.6 0.3 1.4e-05 25.3 0.1 5.5 5 0 0 5 5 5 5 PDZ domain Tricorn_PDZ PF14685.6 CDJ92029.1 - 6.6e-08 32.4 4.2 0.12 12.3 0.1 5.4 5 0 0 5 5 5 3 Tricorn protease PDZ domain PDZ_4 PF17816.1 CDJ92029.1 - 8e-05 23.0 0.2 4 7.9 0.0 4.2 4 0 0 4 4 4 1 PDZ domain FYRC PF05965.14 CDJ92029.1 - 0.2 11.9 0.1 6.7 7.0 0.0 3.2 4 0 0 4 4 4 0 F/Y rich C-terminus OB_RNB PF08206.11 CDJ92029.1 - 0.22 11.2 2.0 3.1 7.6 0.0 3.3 4 0 0 4 4 4 0 Ribonuclease B OB domain RabGAP-TBC PF00566.18 CDJ92030.1 - 2.6e-28 99.1 0.5 4.4e-28 98.4 0.5 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain zf-Nse PF11789.8 CDJ92031.1 - 7.9e-11 41.6 0.0 1.9e-10 40.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 CDJ92031.1 - 0.0062 16.5 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CDJ92031.1 - 0.051 13.9 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Ring finger domain zf-MIZ PF02891.20 CDJ92031.1 - 0.17 11.6 0.5 0.58 9.9 0.0 2.1 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger mRNA_cap_enzyme PF01331.19 CDJ92033.1 - 2.1e-64 216.9 0.1 3.3e-64 216.3 0.1 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 CDJ92033.1 - 1.1e-20 74.2 0.0 2.1e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DSPc PF00782.20 CDJ92033.1 - 1.9e-10 40.7 0.0 6.5e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DNA_ligase_A_M PF01068.21 CDJ92033.1 - 6.2e-07 29.3 0.0 0.00015 21.5 0.0 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Y_phosphatase PF00102.27 CDJ92033.1 - 0.011 15.3 0.2 0.04 13.5 0.0 1.9 2 0 0 2 2 2 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CDJ92033.1 - 0.08 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 CDJ92033.1 - 0.097 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PDZ PF00595.24 CDJ92035.1 - 9.5e-60 198.9 2.7 3.1e-19 69.1 0.0 3.5 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.21 CDJ92035.1 - 5.9e-50 169.5 0.1 1.1e-49 168.6 0.1 1.5 1 0 0 1 1 1 1 Guanylate kinase L27_1 PF09058.10 CDJ92035.1 - 1.2e-23 82.8 1.2 1.2e-23 82.8 1.2 1.9 2 0 0 2 2 2 1 L27_1 PDZ_6 PF17820.1 CDJ92035.1 - 3.7e-20 71.5 1.6 1.2e-09 37.8 0.0 3.7 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 CDJ92035.1 - 7.7e-16 58.2 4.7 1.4e-05 25.3 0.2 3.5 3 0 0 3 3 3 3 PDZ domain SH3_1 PF00018.28 CDJ92035.1 - 1.4e-07 31.0 0.0 3.1e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDJ92035.1 - 6.8e-06 25.7 0.0 2.2e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain Tricorn_PDZ PF14685.6 CDJ92035.1 - 0.0013 18.7 3.9 0.069 13.1 0.0 3.7 4 0 0 4 4 4 1 Tricorn protease PDZ domain SH3_9 PF14604.6 CDJ92035.1 - 0.0075 16.1 0.0 0.02 14.7 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain API5 PF05918.11 CDJ92036.1 - 8.1e-48 163.5 11.6 9e-48 163.4 11.6 1.0 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) Fucosidase_C PF16757.5 CDJ92036.1 - 0.013 16.0 0.1 0.088 13.4 0.1 2.2 2 0 0 2 2 2 0 Alpha-L-fucosidase C-terminal domain HEAT_2 PF13646.6 CDJ92036.1 - 0.073 13.5 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 HEAT repeats RasGEF_N_2 PF14663.6 CDJ92036.1 - 0.14 12.6 3.1 0.33 11.4 0.7 2.7 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Cnd1 PF12717.7 CDJ92036.1 - 0.25 11.4 4.3 0.4 10.7 2.1 2.5 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Condensin2nSMC PF12422.8 CDJ92037.1 - 5.7e-22 78.5 0.1 2.1e-21 76.7 0.1 2.1 1 0 0 1 1 1 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.22 CDJ92037.1 - 0.00029 20.8 0.1 7.7 7.1 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat Sec62 PF03839.16 CDJ92038.1 - 0.16 11.5 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 GCS PF03074.16 CDJ92039.1 - 1.4e-170 567.6 0.0 1.7e-170 567.3 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase 2-oxoacid_dh PF00198.23 CDJ92040.1 - 5.6e-81 271.4 0.0 7.4e-81 271.0 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CDJ92040.1 - 1.2e-17 63.5 0.0 2.6e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CDJ92040.1 - 2.5e-11 43.7 2.2 2.7e-11 43.6 0.6 2.0 2 0 0 2 2 2 1 e3 binding domain SEFIR PF08357.11 CDJ92042.1 - 8.9e-12 45.5 0.0 1.4e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 SEFIR domain DEAD PF00270.29 CDJ92044.1 - 5.4e-53 179.4 0.1 1.3e-51 174.9 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ92044.1 - 8.4e-23 80.8 1.0 1.2e-21 77.1 0.1 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain VIT PF08487.10 CDJ92044.1 - 0.14 12.4 1.2 0.32 11.2 1.2 1.6 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain DUF4578 PF15147.6 CDJ92044.1 - 0.73 10.7 4.0 0.91 10.4 1.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4578) Mucin15 PF15672.5 CDJ92045.1 - 0.24 10.8 12.2 0.34 10.4 12.2 1.2 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 Alpha_GJ PF03229.13 CDJ92045.1 - 0.72 10.4 15.0 24 5.5 12.5 2.3 2 0 0 2 2 2 0 Alphavirus glycoprotein J Neur_chan_LBD PF02931.23 CDJ92046.1 - 8.6e-50 169.2 0.1 1e-49 168.9 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ92046.1 - 5.7e-07 29.8 0.1 8.5e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Tetraspanin PF00335.20 CDJ92047.1 - 0.0016 18.2 2.0 0.0025 17.6 2.0 1.3 1 0 0 1 1 1 1 Tetraspanin family Cation_efflux PF01545.21 CDJ92047.1 - 0.017 14.9 4.9 0.015 15.0 3.8 1.4 1 1 0 1 1 1 0 Cation efflux family DUF2207 PF09972.9 CDJ92047.1 - 0.13 11.0 0.8 0.18 10.5 0.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SUR7 PF06687.12 CDJ92047.1 - 0.15 11.7 7.3 0.26 10.9 7.1 1.4 1 1 0 1 1 1 0 SUR7/PalI family GWT1 PF06423.12 CDJ92047.1 - 1.1 9.4 6.0 3 8.0 6.1 1.7 1 1 1 2 2 2 0 GWT1 HRG PF16954.5 CDJ92047.1 - 9.4 6.7 8.8 2.3 8.7 0.6 2.6 2 0 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene LIM PF00412.22 CDJ92048.1 - 9.9e-24 83.3 51.6 3.3e-10 40.1 8.9 4.4 4 1 0 4 4 4 3 LIM domain PET PF06297.14 CDJ92048.1 - 1e-22 80.2 0.0 1.8e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 PET Domain Ground-like PF04155.18 CDJ92050.1 - 2.3e-13 50.6 0.0 2.9e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Ground-like domain Na_Ca_ex PF01699.24 CDJ92051.1 - 1.9e-49 167.5 34.6 5.4e-25 88.1 12.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Calx-beta PF03160.14 CDJ92051.1 - 4.8e-28 97.3 0.3 2.3e-17 63.0 0.1 2.5 2 0 0 2 2 2 2 Calx-beta domain Na_Ca_ex_C PF16494.5 CDJ92051.1 - 3.5e-05 24.2 0.0 0.0001 22.8 0.0 1.7 1 0 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain G8 PF10162.9 CDJ92051.1 - 0.049 13.7 0.1 0.15 12.1 0.1 1.8 1 0 0 1 1 1 0 G8 domain DUF4843 PF16132.5 CDJ92051.1 - 0.12 11.9 0.4 9.4 5.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4843) Ground-like PF04155.18 CDJ92052.1 - 5.2e-15 55.9 1.6 6.8e-15 55.5 1.6 1.1 1 0 0 1 1 1 1 Ground-like domain DUF3498 PF12004.8 CDJ92053.1 - 0.008 15.4 3.9 0.01 15.0 3.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3498) E2_bind PF08825.10 CDJ92053.1 - 0.0089 16.2 1.1 0.076 13.2 0.0 2.3 2 0 0 2 2 2 1 E2 binding domain SHE3 PF17078.5 CDJ92053.1 - 0.091 12.5 4.1 0.048 13.4 2.1 1.5 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 LIAS_N PF16881.5 CDJ92054.1 - 1.3e-22 80.3 0.8 2e-22 79.6 0.2 1.6 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 CDJ92054.1 - 1.6e-08 35.1 0.1 3e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily ORC5_C PF14630.6 CDJ92055.1 - 6e-33 114.6 0.1 1.6e-32 113.2 0.1 1.7 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus DUF496 PF04363.12 CDJ92055.1 - 0.075 13.1 0.1 0.19 11.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF496) Exo_endo_phos_2 PF14529.6 CDJ92056.1 - 0.0011 18.8 0.0 0.0027 17.5 0.0 1.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Methyltransf_PK PF05891.12 CDJ92057.1 - 4.6e-74 248.6 0.0 5.5e-74 248.4 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 CDJ92057.1 - 2.7e-06 28.0 0.0 5.2e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ92057.1 - 5.7e-05 23.7 0.0 9.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ92057.1 - 0.027 15.2 0.0 0.058 14.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 CDJ92057.1 - 0.049 12.7 0.0 0.072 12.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 CDJ92057.1 - 0.053 12.8 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Pkinase_Tyr PF07714.17 CDJ92059.1 - 4.1e-72 242.6 0.0 5.3e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ92059.1 - 8.7e-45 153.1 0.0 1.2e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDJ92059.1 - 4.7e-10 39.4 0.0 2.1e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 SH2 domain Motile_Sperm PF00635.26 CDJ92060.1 - 3.3e-05 23.7 0.1 5.9e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain zf-RING_5 PF14634.6 CDJ92061.1 - 4.2 7.4 7.3 19 5.3 7.3 2.1 1 1 0 1 1 1 0 zinc-RING finger domain DUF1907 PF08925.11 CDJ92062.1 - 0.066 12.6 0.0 0.12 11.8 0.0 1.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1907) WD40 PF00400.32 CDJ92063.1 - 4.5e-09 36.8 0.3 8e-05 23.3 0.2 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat NIPSNAP PF07978.13 CDJ92063.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 NIPSNAP HSP70 PF00012.20 CDJ92064.1 - 2.2e-108 363.0 0.0 2.7e-108 362.8 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CDJ92064.1 - 1e-15 57.4 0.2 3.5e-15 55.7 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein StbA PF06406.11 CDJ92064.1 - 0.0033 16.7 0.0 0.0092 15.2 0.0 1.9 2 0 0 2 2 2 1 StbA protein Raco_middle PF17651.1 CDJ92064.1 - 0.022 14.4 0.0 0.38 10.4 0.0 2.4 2 0 0 2 2 2 0 RACo middle region FtsA PF14450.6 CDJ92064.1 - 0.061 13.7 0.2 4.1 7.9 0.0 3.0 2 1 0 2 2 2 0 Cell division protein FtsA DDR PF08841.10 CDJ92064.1 - 0.068 12.1 0.4 0.47 9.4 0.1 2.3 3 0 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain Actin PF00022.19 CDJ92064.1 - 0.092 11.3 0.1 3.7 6.0 0.0 2.1 1 1 1 2 2 2 0 Actin BcrAD_BadFG PF01869.20 CDJ92064.1 - 0.11 11.9 0.0 1 8.8 0.0 2.3 2 1 1 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 CDJ92064.1 - 0.13 11.5 0.1 0.25 10.5 0.1 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase DUF1759 PF03564.15 CDJ92065.1 - 2.9e-29 101.9 3.5 5.4e-29 101.0 3.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) CREPT PF16566.5 CDJ92065.1 - 0.36 11.0 4.8 1.1 9.4 0.6 2.6 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Pkinase_Tyr PF07714.17 CDJ92066.1 - 2.2e-50 171.4 0.0 2.5e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ92066.1 - 8.4e-25 87.6 0.0 1e-24 87.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Glutaredoxin PF00462.24 CDJ92069.1 - 4.5e-17 62.0 0.1 7.8e-17 61.3 0.1 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 CDJ92069.1 - 0.00057 20.3 0.2 0.0012 19.3 0.2 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 CDJ92069.1 - 0.00082 19.7 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 CDJ92069.1 - 0.0012 18.8 0.0 0.0027 17.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.6 CDJ92069.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin GST_N_3 PF13417.6 CDJ92069.1 - 0.15 12.5 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Apyrase PF06079.11 CDJ92070.1 - 4.6e-101 337.9 0.4 5.5e-101 337.6 0.4 1.0 1 0 0 1 1 1 1 Apyrase Trehalose_PPase PF02358.16 CDJ92070.1 - 0.039 13.1 0.1 0.06 12.5 0.1 1.2 1 0 0 1 1 1 0 Trehalose-phosphatase Glutaredoxin PF00462.24 CDJ92071.1 - 2.8e-18 65.9 0.0 4.2e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 CDJ92071.1 - 0.00062 20.1 0.0 0.00071 19.9 0.0 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 CDJ92071.1 - 0.0018 18.7 0.2 0.0032 17.9 0.2 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 CDJ92071.1 - 0.0026 17.8 0.0 0.0076 16.3 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin domain DSBA PF01323.20 CDJ92071.1 - 0.033 14.0 0.1 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 DSBA-like thioredoxin domain GST_N_2 PF13409.6 CDJ92071.1 - 0.035 14.4 0.0 0.042 14.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CDJ92071.1 - 0.054 13.9 0.0 0.089 13.2 0.0 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Hormone_2 PF00123.20 CDJ92071.1 - 0.15 12.0 0.0 7.1 6.6 0.0 2.5 2 0 0 2 2 2 0 Peptide hormone Glutaredoxin PF00462.24 CDJ92072.1 - 3.7e-15 55.9 0.0 5.9e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 CDJ92072.1 - 0.0037 17.7 0.1 0.0064 16.9 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 CDJ92072.1 - 0.011 15.5 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF3291 PF11695.8 CDJ92072.1 - 0.02 14.6 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3291) DUF836 PF05768.14 CDJ92072.1 - 0.079 13.4 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Ldl_recept_a PF00057.18 CDJ92073.1 - 2.2e-08 34.2 10.0 3.8e-08 33.4 10.0 1.4 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A YwiC PF14256.6 CDJ92073.1 - 0.037 14.3 0.3 0.098 13.0 0.2 1.6 2 0 0 2 2 2 0 YwiC-like protein N_methyl PF07963.12 CDJ92073.1 - 0.55 9.9 5.1 1.4 8.6 5.1 1.7 1 0 0 1 1 1 0 Prokaryotic N-terminal methylation motif AAA PF00004.29 CDJ92074.1 - 8.9e-40 136.2 0.0 1.5e-39 135.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CDJ92074.1 - 2.6e-25 88.2 0.3 1.1e-24 86.2 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 CDJ92074.1 - 1.5e-21 76.2 4.2 1.5e-21 76.2 4.2 2.0 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 CDJ92074.1 - 3.3e-07 30.0 0.0 1.2e-06 28.2 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CDJ92074.1 - 2.1e-05 25.0 0.1 0.014 15.8 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 CDJ92074.1 - 3.4e-05 23.6 0.0 8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 CDJ92074.1 - 4.4e-05 23.7 0.1 0.00076 19.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 CDJ92074.1 - 6.7e-05 22.3 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 CDJ92074.1 - 0.00012 22.3 0.2 0.017 15.4 0.0 2.7 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 CDJ92074.1 - 0.00018 21.3 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 CDJ92074.1 - 0.00029 20.9 0.0 0.00073 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CDJ92074.1 - 0.00041 20.4 0.0 0.0011 19.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 CDJ92074.1 - 0.00045 19.5 0.0 0.00076 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 CDJ92074.1 - 0.0017 18.9 0.0 0.0057 17.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDJ92074.1 - 0.007 16.5 0.0 0.025 14.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CDJ92074.1 - 0.009 15.5 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_17 PF13207.6 CDJ92074.1 - 0.017 15.6 0.2 0.2 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CDJ92074.1 - 0.017 15.5 0.2 0.069 13.6 0.0 2.2 3 0 0 3 3 1 0 RNA helicase TniB PF05621.11 CDJ92074.1 - 0.018 14.4 0.0 5.1 6.4 0.0 2.3 1 1 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 CDJ92074.1 - 0.027 14.2 0.0 0.067 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CDJ92074.1 - 0.038 13.3 0.2 5.5 6.3 0.0 2.4 1 1 1 2 2 2 0 KaiC Mg_chelatase PF01078.21 CDJ92074.1 - 0.045 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 CDJ92074.1 - 0.046 13.2 0.1 0.11 12.0 0.1 1.7 1 1 0 1 1 1 0 PhoH-like protein HEPN PF05168.14 CDJ92074.1 - 0.046 13.8 0.5 0.12 12.5 0.5 1.7 1 0 0 1 1 1 0 HEPN domain AAA_25 PF13481.6 CDJ92074.1 - 0.055 13.1 0.1 2.8 7.4 0.1 2.4 1 1 1 2 2 2 0 AAA domain ResIII PF04851.15 CDJ92074.1 - 0.057 13.4 0.5 0.36 10.8 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 CDJ92074.1 - 0.064 13.0 0.0 0.24 11.1 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 CDJ92074.1 - 0.15 12.2 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TPR_1 PF00515.28 CDJ92074.1 - 0.15 11.9 0.8 0.54 10.2 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_30 PF13604.6 CDJ92074.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Lipoprotein_10 PF03202.13 CDJ92074.1 - 0.6 10.6 4.3 1.3 9.5 4.3 1.5 1 0 0 1 1 1 0 Putative mycoplasma lipoprotein, C-terminal region G-alpha PF00503.20 CDJ92075.1 - 5.8e-103 344.8 0.8 7.2e-103 344.4 0.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDJ92075.1 - 2.1e-15 56.6 2.5 2.8e-12 46.4 0.8 2.4 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ92075.1 - 8.6e-06 25.3 0.5 0.0009 18.7 0.1 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 CDJ92075.1 - 4.5e-05 23.6 0.4 0.034 14.4 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 CDJ92075.1 - 0.038 13.4 0.2 0.064 12.7 0.2 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 CDJ92075.1 - 0.038 13.7 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CDJ92075.1 - 0.1 12.5 0.3 15 5.5 0.0 2.6 2 1 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 CDJ92075.1 - 0.13 11.8 0.0 1.9 8.0 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 CDJ92075.1 - 0.14 11.5 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Polysacc_synt_4 PF04669.13 CDJ92076.1 - 4.9e-16 58.8 0.2 5.1e-09 36.0 0.0 2.1 1 1 1 2 2 2 2 Polysaccharide biosynthesis Nucleoporin_FG PF13634.6 CDJ92077.1 - 6.7e-56 187.1 346.2 4.1e-09 37.2 30.6 9.9 2 2 9 11 11 11 11 Nucleoporin FG repeat region Nucleoporin_FG2 PF15967.5 CDJ92077.1 - 4.8e-13 48.5 44.2 4.8e-13 48.5 44.2 4.9 2 1 3 5 5 5 1 Nucleoporin FG repeated region RRF_GI PF12614.8 CDJ92077.1 - 0.0014 18.7 0.5 0.0028 17.8 0.4 1.5 1 1 0 1 1 1 1 Ribosome recycling factor SLAM PF06214.11 CDJ92077.1 - 0.019 15.0 0.1 0.035 14.1 0.1 1.3 1 0 0 1 1 1 0 Signaling lymphocytic activation molecule (SLAM) protein IKBKB_SDD PF18397.1 CDJ92077.1 - 0.07 12.4 3.0 0.11 11.8 2.5 1.5 1 1 1 2 2 2 0 IQBAL scaffold dimerization domain Mod_r PF07200.13 CDJ92077.1 - 0.15 12.2 0.7 0.26 11.4 0.7 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein NPV_P10 PF05531.12 CDJ92077.1 - 0.2 12.2 0.2 0.7 10.4 0.0 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Plug_translocon PF10559.9 CDJ92077.1 - 1.2 9.1 13.3 15 5.6 0.0 7.6 7 0 0 7 7 7 0 Plug domain of Sec61p Pkinase PF00069.25 CDJ92078.1 - 7.4e-65 218.9 0.0 9e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ92078.1 - 5.5e-32 111.1 0.1 7.6e-32 110.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ92078.1 - 0.00052 19.4 0.1 0.064 12.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 CDJ92078.1 - 0.0022 17.0 0.3 0.0034 16.4 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain TPR_19 PF14559.6 CDJ92081.1 - 1.6e-08 34.9 0.6 0.054 14.0 0.1 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ92081.1 - 2.3e-05 24.8 2.8 1.1 10.3 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ92081.1 - 2.5e-05 24.1 0.0 0.9 9.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ92081.1 - 6.5e-05 23.3 2.7 2.6 8.9 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ92081.1 - 0.00014 21.8 0.0 0.06 13.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ92081.1 - 0.00029 20.5 0.1 3.6 7.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.9 CDJ92081.1 - 0.0024 17.6 0.6 0.036 13.8 0.1 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 CDJ92081.1 - 0.0046 16.4 0.2 0.011 15.2 0.2 1.6 2 0 0 2 2 2 1 MalT-like TPR region TPR_16 PF13432.6 CDJ92081.1 - 0.018 15.7 3.6 4.9 7.9 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ92081.1 - 0.02 15.1 1.1 0.074 13.3 0.1 2.5 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 JAB PF01398.21 CDJ92083.1 - 2.6e-32 111.3 0.0 5.5e-32 110.2 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CDJ92083.1 - 4.5e-15 56.0 0.5 9.1e-15 55.1 0.5 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 CDJ92083.1 - 4.8e-06 26.3 0.0 7.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Neur_chan_memb PF02932.16 CDJ92084.1 - 3.7e-22 79.6 1.7 6.9e-18 65.6 0.5 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF1759 PF03564.15 CDJ92085.1 - 1.7e-23 83.2 0.4 1.7e-23 83.2 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 CDJ92085.1 - 9.6e-11 41.7 3.2 0.00026 20.8 0.0 3.4 3 2 1 4 4 4 2 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 CDJ92085.1 - 5.9e-08 33.2 0.1 0.026 15.1 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 CDJ92085.1 - 7e-08 32.9 0.1 0.013 16.0 0.1 2.9 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ92085.1 - 5.8e-05 22.9 0.1 0.39 10.5 0.0 2.4 2 0 0 2 2 2 2 Retroviral aspartyl protease zf-CCHC PF00098.23 CDJ92085.1 - 0.00063 19.7 21.6 0.016 15.3 2.7 3.5 3 0 0 3 3 3 2 Zinc knuckle RVP PF00077.20 CDJ92085.1 - 0.002 18.4 0.0 3.6 8.0 0.0 2.6 2 0 0 2 2 2 2 Retroviral aspartyl protease zf-CCHC_5 PF14787.6 CDJ92085.1 - 0.034 13.9 10.0 0.75 9.6 1.6 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger GrpE PF01025.19 CDJ92085.1 - 0.61 9.7 3.7 0.42 10.2 0.3 2.2 2 0 0 2 2 2 0 GrpE RVT_1 PF00078.27 CDJ92086.1 - 1.8e-05 24.4 0.1 3.4e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CAP PF00188.26 CDJ92088.1 - 1.2e-07 32.7 0.9 1.9e-07 32.0 0.9 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CDJ92089.1 - 2.5e-17 63.9 4.8 3.6e-17 63.4 4.8 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family WD40 PF00400.32 CDJ92090.1 - 1.6e-12 47.7 4.7 0.0012 19.6 0.3 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ92090.1 - 0.0043 17.3 0.0 4.3 7.7 0.0 3.3 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CDJ92090.1 - 0.011 16.2 0.8 18 6.0 0.0 4.5 4 0 0 4 4 4 0 PQQ-like domain Cytochrom_D1 PF02239.16 CDJ92090.1 - 0.022 13.3 0.0 0.83 8.1 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Gly_rich PF12810.7 CDJ92090.1 - 0.42 10.5 2.6 5.4 6.9 0.1 2.5 2 1 0 2 2 2 0 Glycine rich protein Tropomyosin PF00261.20 CDJ92091.1 - 6.3e-106 353.1 79.2 1.1e-85 286.8 50.4 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 CDJ92091.1 - 1.1e-26 93.7 76.6 3.6e-13 49.9 14.8 3.9 1 1 1 3 3 3 3 Tropomyosin like Laminin_II PF06009.12 CDJ92091.1 - 3e-05 24.1 39.8 0.028 14.4 2.1 4.4 1 1 4 5 5 5 4 Laminin Domain II DUF745 PF05335.13 CDJ92091.1 - 4.9e-05 23.1 54.2 0.023 14.4 17.1 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF745) Uds1 PF15456.6 CDJ92091.1 - 0.0015 18.7 51.3 0.019 15.1 18.1 3.4 1 1 2 3 3 3 3 Up-regulated During Septation MscS_porin PF12795.7 CDJ92091.1 - 0.076 12.5 53.9 0.044 13.3 29.4 3.5 1 1 3 4 4 4 0 Mechanosensitive ion channel porin domain Fez1 PF06818.15 CDJ92091.1 - 0.11 13.0 57.1 0.05 14.1 23.8 2.2 1 1 1 2 2 2 0 Fez1 DUF1794 PF08768.11 CDJ92091.1 - 0.27 11.2 10.1 7.4 6.5 0.2 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF1794) Golgin_A5 PF09787.9 CDJ92091.1 - 0.33 10.4 60.4 0.1 12.1 12.9 3.3 1 1 2 3 3 3 0 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 CDJ92091.1 - 0.33 11.0 72.2 0.089 12.9 19.3 4.1 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein BST2 PF16716.5 CDJ92091.1 - 0.5 11.0 39.5 0.3 11.7 3.4 4.9 1 1 5 6 6 6 0 Bone marrow stromal antigen 2 Spc7 PF08317.11 CDJ92091.1 - 0.7 8.7 65.6 0.78 8.6 6.7 3.5 1 1 3 4 4 4 0 Spc7 kinetochore protein FPP PF05911.11 CDJ92091.1 - 0.74 7.9 53.1 0.027 12.7 25.3 2.2 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil SlyX PF04102.12 CDJ92091.1 - 1.5 9.5 47.2 0.26 11.9 1.7 6.2 2 1 4 6 6 6 0 SlyX DUF1664 PF07889.12 CDJ92091.1 - 1.6 8.7 32.8 2.2 8.3 5.1 4.2 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 CDJ92091.1 - 2 6.9 50.0 0.74 8.4 13.9 2.5 1 1 2 3 3 3 0 AAA domain Fib_alpha PF08702.10 CDJ92091.1 - 3 8.0 31.5 1.9 8.6 6.0 3.9 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 CDJ92091.1 - 4.2 6.8 41.7 21 4.6 16.9 3.0 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF16 PF01519.16 CDJ92091.1 - 4.4 7.8 38.9 0.19 12.2 3.0 4.6 1 1 2 3 3 2 0 Protein of unknown function DUF16 CENP-F_leu_zip PF10473.9 CDJ92091.1 - 5.9 6.9 67.7 0.093 12.8 28.7 3.5 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 CDJ92091.1 - 5.9 6.5 64.7 0.072 12.8 15.8 3.6 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF4472 PF14739.6 CDJ92091.1 - 9.7 7.0 52.8 0.32 11.7 13.1 4.7 1 1 2 4 4 4 0 Domain of unknown function (DUF4472) zf-C2H2_3rep PF18868.1 CDJ92092.1 - 0.071 13.8 0.9 0.25 12.0 0.9 1.9 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf_C2H2_ZHX PF18387.1 CDJ92092.1 - 8.1 6.2 6.2 1.6 8.4 1.1 2.4 2 1 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-Di19 PF05605.12 CDJ92093.1 - 1.7e-05 25.0 2.7 0.0016 18.7 0.3 3.0 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 CDJ92093.1 - 0.002 18.8 7.4 0.057 14.3 1.2 4.0 3 0 0 3 3 3 1 C2H2-type zinc finger Actin_micro PF17003.5 CDJ92093.1 - 0.0049 16.1 1.2 0.73 9.0 0.0 2.2 1 1 1 2 2 2 2 Putative actin-like family DUF2226 PF09987.9 CDJ92093.1 - 0.058 12.7 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) zf-ribbon_3 PF13248.6 CDJ92093.1 - 0.077 12.4 1.2 0.63 9.5 0.3 2.8 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_2 PF12756.7 CDJ92093.1 - 0.24 11.7 6.4 0.29 11.5 3.8 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Rad50_zn_hook PF04423.14 CDJ92093.1 - 0.3 10.9 0.1 0.3 10.9 0.1 2.3 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C2H2 PF00096.26 CDJ92093.1 - 0.33 11.5 9.8 0.11 13.0 1.2 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CDJ92093.1 - 0.94 9.9 5.9 0.2 12.0 0.5 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Innexin PF00876.18 CDJ92094.1 - 4.1e-69 233.5 10.2 4.7e-69 233.3 10.2 1.0 1 0 0 1 1 1 1 Innexin Sulfotransfer_2 PF03567.14 CDJ92095.1 - 1.2e-07 31.9 2.1 2.4e-07 30.9 0.3 1.9 1 1 1 2 2 2 1 Sulfotransferase family MFS_1 PF07690.16 CDJ92096.1 - 3.3e-07 29.6 36.6 0.00041 19.4 6.4 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ92096.1 - 1.6e-05 24.0 0.1 1.6e-05 24.0 0.1 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter zf-C3HC4_3 PF13920.6 CDJ92097.1 - 1.4e-13 50.4 33.1 3.8e-07 29.9 11.2 2.8 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Ank_4 PF13637.6 CDJ92097.1 - 2.3e-08 34.4 0.2 0.0032 18.0 0.0 3.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ92097.1 - 4.1e-08 33.3 0.5 0.0027 18.0 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ92097.1 - 6.1e-07 29.9 0.2 3.1e-05 24.5 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ92097.1 - 1.7e-06 28.2 1.7 0.0096 16.3 0.1 4.0 3 1 0 3 3 3 2 Ankyrin repeat Prok-RING_4 PF14447.6 CDJ92097.1 - 8.3e-06 25.6 32.6 1.2e-05 25.0 10.1 3.3 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CDJ92097.1 - 0.002 18.1 4.2 0.002 18.1 4.2 4.0 3 1 1 4 4 4 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDJ92097.1 - 0.0043 17.0 29.8 0.039 13.9 10.5 2.9 2 1 0 2 2 2 2 zinc-RING finger domain Ank_3 PF13606.6 CDJ92097.1 - 0.0074 16.7 8.6 0.073 13.7 0.0 5.0 6 1 0 6 6 5 1 Ankyrin repeat zf-C3HC4_2 PF13923.6 CDJ92097.1 - 0.03 14.2 30.7 0.051 13.4 10.8 3.6 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ92097.1 - 0.071 13.0 29.5 0.18 11.7 4.3 3.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Ank_4 PF13637.6 CDJ92098.1 - 5.5e-16 58.7 5.5 8.8e-06 26.2 0.1 5.2 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ92098.1 - 3.6e-15 55.8 8.3 3.4e-06 27.2 0.3 3.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ92098.1 - 1.1e-13 51.6 6.9 7.2e-07 29.7 0.3 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDJ92098.1 - 5.6e-11 41.7 4.8 0.011 16.2 0.1 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 CDJ92098.1 - 2.4e-08 34.1 10.6 0.041 14.3 0.1 5.1 5 0 0 5 5 5 3 Ankyrin repeat Dimerisation PF08100.11 CDJ92098.1 - 0.044 13.8 0.1 0.63 10.1 0.0 2.3 2 0 0 2 2 2 0 Dimerisation domain SNF2_N PF00176.23 CDJ92101.1 - 3.9e-37 127.8 0.1 5.7e-37 127.2 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ92101.1 - 8.7e-13 48.6 0.0 2.7e-12 47.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain IFN-gamma PF00714.17 CDJ92101.1 - 0.02 14.7 0.9 0.073 12.9 0.1 2.2 2 0 0 2 2 2 0 Interferon gamma VWA PF00092.28 CDJ92104.1 - 2.3e-05 24.7 1.2 0.00042 20.6 0.1 3.0 3 1 0 3 3 3 1 von Willebrand factor type A domain Mito_carr PF00153.27 CDJ92105.1 - 1.1e-49 166.3 1.0 3.1e-18 65.5 0.0 3.7 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.16 CDJ92105.1 - 3.7e-24 85.3 27.1 7.3e-24 84.3 27.1 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Serine_protease PF18405.1 CDJ92105.1 - 0.034 13.3 0.0 1.5 7.9 0.0 2.8 3 0 0 3 3 3 0 Gammaproteobacterial serine protease SLATT_3 PF18184.1 CDJ92105.1 - 0.55 10.4 1.9 1.4 9.0 0.0 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 NARG2_C PF10505.9 CDJ92106.1 - 0.21 11.1 1.1 0.37 10.3 0.5 1.7 1 1 1 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus CBS PF00571.28 CDJ92107.1 - 0.096 13.1 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 CBS domain Collagen PF01391.18 CDJ92108.1 - 3.7e-221 715.2 747.4 4.4e-09 36.0 28.1 30.3 2 2 25 28 28 28 28 Collagen triple helix repeat (20 copies) C4 PF01413.19 CDJ92108.1 - 2e-80 266.4 3.9 9e-41 138.7 0.2 2.1 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Glyco_hydro_85 PF03644.13 CDJ92109.1 - 1.7e-73 247.7 0.0 2.3e-73 247.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Peptidase_A6 PF01829.16 CDJ92109.1 - 0.23 10.7 0.0 0.34 10.2 0.0 1.1 1 0 0 1 1 1 0 Peptidase A6 family Rab5-bind PF09311.11 CDJ92110.1 - 6.8e-78 262.2 44.1 8.6e-78 261.8 44.1 1.1 1 0 0 1 1 1 1 Rabaptin-like protein FYVE PF01363.21 CDJ92110.1 - 2.4e-05 24.4 10.3 2.4e-05 24.4 10.3 1.9 2 0 0 2 2 2 1 FYVE zinc finger Filament PF00038.21 CDJ92110.1 - 0.00046 19.9 43.6 0.0017 18.0 15.7 3.4 2 1 1 3 3 3 2 Intermediate filament protein UPF0184 PF03670.13 CDJ92110.1 - 0.029 14.8 0.3 0.029 14.8 0.3 3.7 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0184) Mce4_CUP1 PF11887.8 CDJ92110.1 - 0.081 12.4 7.1 0.26 10.7 0.5 2.6 2 1 1 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative Golgin_A5 PF09787.9 CDJ92110.1 - 0.099 12.1 51.2 0.1 12.1 30.2 2.9 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF3540 PF12059.8 CDJ92110.1 - 1.1 9.1 13.3 0.93 9.3 6.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3540) zf-RING_2 PF13639.6 CDJ92110.1 - 2.1 8.7 14.3 4.6 7.6 14.3 1.6 1 0 0 1 1 1 0 Ring finger domain DZR PF12773.7 CDJ92110.1 - 2.1 8.4 10.6 5.4e+02 0.7 11.2 2.7 1 1 1 2 2 2 0 Double zinc ribbon Borrelia_REV PF03978.13 CDJ92110.1 - 4.1 7.3 16.0 0.61 10.0 6.1 3.1 2 1 1 3 3 3 0 Borrelia burgdorferi REV protein DUF4686 PF15742.5 CDJ92110.1 - 7 5.7 51.9 0.43 9.7 15.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) DUF948 PF06103.11 CDJ92110.1 - 7.7 6.8 10.1 5.7 7.3 0.2 3.3 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) PRKG1_interact PF15898.5 CDJ92111.1 - 0.011 16.6 5.6 0.011 16.6 5.6 7.4 2 2 4 7 7 7 0 cGMP-dependent protein kinase interacting domain USP8_interact PF08941.10 CDJ92111.1 - 0.013 15.3 5.0 0.013 15.3 5.0 5.7 2 2 3 6 6 6 0 USP8 interacting KIF1B PF12423.8 CDJ92111.1 - 0.34 11.4 4.1 0.35 11.3 0.1 3.2 3 0 0 3 3 3 0 Kinesin protein 1B UPF0167 PF03691.14 CDJ92111.1 - 0.68 9.7 3.5 3.8 7.3 0.1 3.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0167) Bap31_Bap29_C PF18035.1 CDJ92111.1 - 1.3 9.1 48.7 0.062 13.3 7.6 7.4 7 1 0 7 7 7 0 Bap31/Bap29 cytoplasmic coiled-coil domain HALZ PF02183.18 CDJ92113.1 - 0.027 14.7 3.5 0.027 14.7 3.5 3.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF4407 PF14362.6 CDJ92113.1 - 0.052 12.9 2.5 0.076 12.3 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sec2p PF06428.11 CDJ92113.1 - 0.072 13.1 3.3 0.1 12.6 1.6 2.0 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Csm1_N PF18504.1 CDJ92113.1 - 0.77 10.1 6.0 0.64 10.4 0.5 2.9 2 1 1 3 3 3 0 Csm1 N-terminal domain ATG16 PF08614.11 CDJ92113.1 - 0.88 9.8 15.1 0.23 11.6 2.3 2.7 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 CDJ92113.1 - 1.8 8.4 8.0 4 7.3 0.8 3.2 2 1 1 3 3 3 0 Septum formation initiator DUF4140 PF13600.6 CDJ92113.1 - 3.2 8.3 6.7 29 5.2 2.8 2.8 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) TTR-52 PF01060.23 CDJ92114.1 - 7.2e-27 93.9 0.0 9.5e-27 93.5 0.0 1.2 1 0 0 1 1 1 1 Transthyretin-like family Transthyretin PF00576.21 CDJ92114.1 - 0.14 12.9 0.0 0.2 12.3 0.0 1.3 1 0 0 1 1 1 0 HIUase/Transthyretin family TTR-52 PF01060.23 CDJ92115.1 - 5.6e-26 91.0 0.0 7.1e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Transthyretin-like family CarboxypepD_reg PF13620.6 CDJ92115.1 - 0.012 15.8 0.2 0.21 11.9 0.1 2.1 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain C6 PF01681.17 CDJ92116.1 - 0.00016 22.1 0.1 0.00016 22.1 0.1 1.1 1 0 0 1 1 1 1 C6 domain DUF281 PF03436.13 CDJ92116.1 - 0.00032 21.0 3.2 0.0016 18.8 3.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF281) Sin3_corepress PF08295.12 CDJ92118.1 - 4.5e-37 126.0 0.2 1e-36 124.9 0.2 1.6 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 CDJ92118.1 - 6.4e-36 122.2 1.0 5.4e-15 55.3 0.0 3.9 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3a_C PF16879.5 CDJ92118.1 - 0.00051 19.8 3.7 0.0056 16.4 0.0 3.7 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein DUF871 PF05913.11 CDJ92118.1 - 0.038 13.2 0.9 0.064 12.4 0.0 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF871) Vps5 PF09325.10 CDJ92119.1 - 2.8e-67 226.7 13.5 3.8e-67 226.3 13.5 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 CDJ92119.1 - 4.2e-20 71.8 0.0 1e-19 70.6 0.0 1.7 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.9 CDJ92119.1 - 0.00011 21.7 1.5 0.0039 16.7 1.2 2.6 1 1 1 2 2 2 1 WASP-binding domain of Sorting nexin protein Pou PF00157.17 CDJ92119.1 - 0.028 14.4 0.5 5.7 7.0 0.2 2.6 2 0 0 2 2 2 0 Pou domain - N-terminal to homeobox domain Mustang PF15682.5 CDJ92119.1 - 0.094 12.8 0.1 0.32 11.1 0.1 1.9 1 0 0 1 1 1 0 Musculoskeletal, temporally activated-embryonic nuclear protein 1 eIF3_N PF09440.10 CDJ92119.1 - 0.12 12.8 2.3 0.23 11.9 0.3 2.3 1 1 0 2 2 2 0 eIF3 subunit 6 N terminal domain FlaC_arch PF05377.11 CDJ92119.1 - 0.14 12.6 0.1 4.6 7.7 0.0 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FAM92 PF06730.11 CDJ92119.1 - 0.16 11.4 5.0 0.046 13.1 1.7 1.7 2 0 0 2 2 2 0 FAM92 protein DUF2203 PF09969.9 CDJ92119.1 - 0.24 12.1 6.8 0.51 11.1 1.2 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Seryl_tRNA_N PF02403.22 CDJ92119.1 - 0.45 10.8 7.6 2.1 8.6 2.2 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Ras PF00071.22 CDJ92120.1 - 1.1e-35 122.6 0.1 1.3e-35 122.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ92120.1 - 2.5e-15 56.7 0.0 4.8e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ92120.1 - 1e-10 41.4 0.0 1.6e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDJ92120.1 - 6.3e-07 29.1 0.1 3.1e-06 26.9 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDJ92120.1 - 1e-05 25.6 0.0 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ92120.1 - 1.2e-05 25.3 0.0 0.0028 17.6 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase G-alpha PF00503.20 CDJ92120.1 - 0.014 14.6 0.1 0.36 9.9 0.0 2.1 1 1 0 2 2 2 0 G-protein alpha subunit Dynamin_N PF00350.23 CDJ92120.1 - 0.014 15.5 0.1 2.8 8.0 0.0 2.6 2 1 1 3 3 3 0 Dynamin family ImcF-related_N PF14331.6 CDJ92120.1 - 0.019 14.3 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 ImcF-related N-terminal domain AAA_14 PF13173.6 CDJ92120.1 - 0.023 14.8 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 CDJ92120.1 - 0.028 13.8 0.0 7.6 5.9 0.1 2.4 2 1 0 2 2 2 0 Bacterial TniB protein Thioredoxin_6 PF13848.6 CDJ92120.1 - 0.036 14.0 0.1 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like domain AAA_25 PF13481.6 CDJ92120.1 - 0.051 13.2 0.0 0.17 11.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain NOG1 PF06858.14 CDJ92120.1 - 0.086 12.6 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) FtsK_SpoIIIE PF01580.18 CDJ92120.1 - 0.12 11.7 0.3 3.4 7.0 0.0 2.4 2 1 1 3 3 3 0 FtsK/SpoIIIE family PH PF00169.29 CDJ92121.1 - 8.4e-13 48.8 0.2 1.8e-12 47.6 0.2 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CDJ92121.1 - 5.3e-12 45.8 0.3 9.4e-12 45.1 0.3 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 CDJ92121.1 - 8e-06 26.2 2.1 0.00055 20.3 2.0 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain Cas9_PI PF16595.5 CDJ92121.1 - 0.012 15.5 0.1 0.015 15.2 0.1 1.2 1 0 0 1 1 1 0 PAM-interacting domain of CRISPR-associated endonuclease Cas9 PH_6 PF15406.6 CDJ92121.1 - 0.023 15.0 0.0 0.06 13.6 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain DUF5519 PF17648.1 CDJ92121.1 - 0.025 14.4 0.1 0.047 13.5 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5519) Mce4_CUP1 PF11887.8 CDJ92121.1 - 0.077 12.4 0.1 0.38 10.2 0.1 1.9 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative SlyX PF04102.12 CDJ92121.1 - 0.3 11.7 3.7 3.7 8.2 0.2 3.1 3 0 0 3 3 3 0 SlyX MbeD_MobD PF04899.12 CDJ92121.1 - 2.7 8.2 7.4 1.2 9.3 0.4 3.2 3 0 0 3 3 3 0 MbeD/MobD like Cyclin_N PF00134.23 CDJ92122.1 - 7.6e-13 48.3 0.2 1.4e-12 47.4 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CDJ92122.1 - 2.2e-08 34.6 0.0 3.1e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin PITH PF06201.13 CDJ92123.1 - 9.4e-38 129.8 0.0 1.1e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain zf-C3HC4_2 PF13923.6 CDJ92124.1 - 9.7e-10 38.1 3.4 2.5e-09 36.8 3.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ92124.1 - 0.00026 21.2 4.8 0.00051 20.3 4.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CDJ92124.1 - 0.00033 20.5 5.4 0.00069 19.4 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RAWUL PF16207.5 CDJ92124.1 - 0.00086 19.9 0.0 0.0015 19.2 0.0 1.4 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_3 PF13920.6 CDJ92124.1 - 0.0012 18.6 4.5 0.0019 18.0 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ92124.1 - 0.0015 18.5 3.6 0.0015 18.5 3.6 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.6 CDJ92124.1 - 0.0016 18.3 2.9 0.0033 17.3 2.9 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 CDJ92124.1 - 0.018 15.2 3.8 0.032 14.3 3.8 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_5 PF14634.6 CDJ92124.1 - 0.032 14.2 6.3 0.06 13.3 6.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 CDJ92124.1 - 0.17 12.2 0.8 0.41 11.0 0.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-Nse PF11789.8 CDJ92124.1 - 0.18 11.7 2.0 0.37 10.6 2.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 CDJ92124.1 - 0.49 10.3 4.5 1 9.3 4.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CDJ92124.1 - 0.57 10.4 8.3 0.25 11.6 5.1 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING MTHFR_C PF12225.8 CDJ92124.1 - 0.59 9.8 4.2 1.2 8.9 4.2 1.4 1 0 0 1 1 1 0 Methylene-tetrahydrofolate reductase C terminal Chromo PF00385.24 CDJ92125.1 - 1e-15 57.3 1.1 2e-15 56.4 1.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CBX7_C PF17218.3 CDJ92125.1 - 0.00034 20.2 0.0 0.00088 18.9 0.0 1.7 1 0 0 1 1 1 1 CBX family C-terminal motif Mtf2_C PF14061.6 CDJ92125.1 - 0.034 14.3 0.5 0.069 13.3 0.5 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 PDCD2_C PF04194.13 CDJ92125.1 - 0.048 13.7 0.3 0.048 13.7 0.3 2.2 1 1 1 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain Titin_Ig-rpts PF06582.12 CDJ92125.1 - 0.12 12.3 0.9 0.26 11.3 0.9 1.4 1 0 0 1 1 1 0 Titin repeat Band_3_cyto PF07565.13 CDJ92127.1 - 3.4e-10 40.2 0.1 8.6e-10 38.9 0.0 1.6 2 0 0 2 2 2 1 Band 3 cytoplasmic domain Nuc_sug_transp PF04142.15 CDJ92129.1 - 3.9e-38 131.4 10.7 4.3e-38 131.2 10.7 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter THOC7 PF05615.13 CDJ92130.1 - 5.9e-16 58.9 9.5 5.9e-16 58.9 9.5 2.3 1 1 1 2 2 2 1 Tho complex subunit 7 FliJ PF02050.16 CDJ92130.1 - 0.016 15.4 17.1 0.41 10.9 5.9 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein TMPIT PF07851.13 CDJ92130.1 - 0.15 11.2 7.4 0.2 10.9 7.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein FapA PF03961.13 CDJ92130.1 - 0.79 8.3 7.7 1 7.9 7.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1664 PF07889.12 CDJ92130.1 - 0.88 9.6 7.0 1.9 8.5 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ssDNA_DBD PF18333.1 CDJ92130.1 - 1.4 9.1 8.0 0.086 12.9 0.5 2.3 2 1 0 2 2 2 0 Non-canonical single-stranded DNA-binding domain V_ATPase_I PF01496.19 CDJ92130.1 - 5.5 4.8 15.1 9.4 4.0 14.9 1.5 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF4200 PF13863.6 CDJ92130.1 - 6.1 7.3 23.5 1.4 9.3 8.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) FUSC PF04632.12 CDJ92130.1 - 8.8 4.7 8.4 11 4.4 8.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ribo_biogen_C PF04034.13 CDJ92131.1 - 2.7e-38 130.5 0.0 4.7e-38 129.8 0.0 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal Kdo PF06293.14 CDJ92131.1 - 4.2e-09 36.1 0.0 7.1e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ92131.1 - 5.5e-09 36.3 0.2 0.00012 22.1 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 CDJ92131.1 - 3.3e-08 33.4 0.0 5.4e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 CDJ92131.1 - 4.2e-06 26.3 0.0 5.7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EcKinase PF02958.20 CDJ92131.1 - 0.0016 17.8 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase_Tyr PF07714.17 CDJ92131.1 - 0.0029 16.9 0.0 0.0045 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Tyr-DNA_phospho PF06087.12 CDJ92132.1 - 1.2e-39 136.4 0.0 3.6e-26 92.0 0.0 2.0 1 1 1 2 2 2 2 Tyrosyl-DNA phosphodiesterase PLDc PF00614.22 CDJ92132.1 - 0.0083 16.3 0.2 0.039 14.1 0.0 2.2 2 0 0 2 2 2 1 Phospholipase D Active site motif Peptidase_C48 PF02902.19 CDJ92133.1 - 6.8e-16 58.8 0.1 1.9e-15 57.3 0.1 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Acetyltransf_14 PF03421.16 CDJ92133.1 - 0.07 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase DUF4489 PF14879.6 CDJ92133.1 - 0.12 12.5 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4489) SHQ1 PF04925.15 CDJ92134.1 - 5.7e-53 179.1 0.1 8.3e-53 178.5 0.1 1.2 1 0 0 1 1 1 1 SHQ1 protein MIase PF02426.16 CDJ92135.1 - 0.12 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Muconolactone delta-isomerase SCVP PF17619.2 CDJ92136.1 - 2.5e-16 60.3 0.1 3.2e-16 60.0 0.1 1.1 1 0 0 1 1 1 1 Secreted clade V proteins CwfJ_C_2 PF04676.14 CDJ92137.1 - 1.7e-14 54.5 0.0 9.9e-14 52.0 0.0 1.9 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 CDJ92137.1 - 7.1e-14 51.7 0.0 9.4e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 I-set PF07679.16 CDJ92138.1 - 0.046 13.8 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain CAP PF00188.26 CDJ92140.1 - 2.5e-34 118.8 18.8 3.1e-18 66.8 6.0 2.2 2 0 0 2 2 2 2 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ92140.1 - 0.00071 19.8 5.0 0.21 11.9 0.2 3.1 2 1 0 2 2 2 2 Ancylostoma-associated secreted protein related Toxin_12 PF07740.12 CDJ92140.1 - 0.22 12.3 20.3 2 9.2 5.7 2.9 2 0 0 2 2 2 0 Ion channel inhibitory toxin Metallothio_Euk PF12749.7 CDJ92140.1 - 1.1 9.5 18.2 1.6 9.0 5.4 2.7 2 0 0 2 2 2 0 Eukaryotic metallothionein Baculo_PEP_C PF04513.12 CDJ92141.1 - 0.0022 18.0 0.4 0.0044 17.1 0.4 1.5 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 CDJ92141.1 - 0.019 15.2 0.1 0.019 15.2 0.1 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ANAPC4 PF12896.7 CDJ92141.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 VirB3 PF05101.13 CDJ92141.1 - 0.1 12.8 0.6 0.15 12.3 0.6 1.2 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Anophelin PF10731.9 CDJ92141.1 - 0.27 11.1 1.7 0.5 10.3 0.3 2.2 2 1 0 2 2 2 0 Thrombin inhibitor from mosquito GP41 PF00517.17 CDJ92141.1 - 0.8 9.6 4.0 1.6 8.6 4.0 1.4 1 1 0 1 1 1 0 Retroviral envelope protein DUF4349 PF14257.6 CDJ92142.1 - 0.016 14.7 0.3 0.022 14.2 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Metallophos PF00149.28 CDJ92143.1 - 9.8e-30 104.6 0.1 1.8e-29 103.7 0.0 1.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase LNS2 PF08235.13 CDJ92144.1 - 6.4e-87 290.7 0.0 2.6e-86 288.8 0.0 1.9 1 1 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 CDJ92144.1 - 1.7e-41 140.3 0.0 2.9e-41 139.6 0.0 1.4 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 CDJ92144.1 - 0.1 12.1 0.5 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF1930 PF09122.10 CDJ92144.1 - 0.17 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1930) Rhomboid PF01694.22 CDJ92145.1 - 9.1e-31 106.9 10.5 1.6e-30 106.1 10.5 1.4 1 0 0 1 1 1 1 Rhomboid family Polysacc_synt_C PF14667.6 CDJ92145.1 - 2.6 8.1 8.7 2.6 8.1 5.5 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain DUF2614 PF11023.8 CDJ92145.1 - 7 6.8 6.8 0.7 10.0 0.3 2.3 2 0 0 2 2 2 0 Zinc-ribbon containing domain BRICHOS PF04089.14 CDJ92146.1 - 0.00019 21.6 0.2 0.0008 19.6 0.0 2.2 2 0 0 2 2 2 1 BRICHOS domain Glyco_hydro_59M PF17387.2 CDJ92146.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 central domain APS_kinase PF01583.20 CDJ92147.1 - 2.7e-71 238.6 0.0 4e-71 238.0 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 CDJ92147.1 - 6.5e-39 133.2 0.0 1.2e-38 132.3 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.6 CDJ92147.1 - 3.9e-06 27.1 0.0 8.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CDJ92147.1 - 0.0026 18.3 0.1 0.0058 17.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 CDJ92147.1 - 0.0056 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 NTPase PRK PF00485.18 CDJ92147.1 - 0.052 13.3 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family TIP49 PF06068.13 CDJ92147.1 - 0.089 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain CbiA PF01656.23 CDJ92147.1 - 0.14 12.3 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.6 CDJ92147.1 - 0.21 11.4 0.1 0.4 10.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ank_2 PF12796.7 CDJ92148.1 - 3e-96 316.1 21.2 8.3e-17 61.6 0.5 9.2 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ92148.1 - 1.3e-92 300.5 37.7 3.3e-06 27.3 0.4 17.2 16 1 0 16 16 16 15 Ankyrin repeat Ank_4 PF13637.6 CDJ92148.1 - 2.9e-88 289.2 20.1 2.7e-13 50.1 0.3 11.8 3 2 10 13 13 13 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ92148.1 - 5e-87 284.8 26.9 4.4e-12 46.0 0.1 12.1 4 4 8 12 12 12 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ92148.1 - 1e-80 255.9 21.1 6e-06 26.2 0.0 16.7 16 1 1 17 17 17 13 Ankyrin repeat UPA_2 PF17809.1 CDJ92148.1 - 4.7e-45 152.6 0.0 9.8e-45 151.6 0.0 1.6 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 CDJ92148.1 - 4.5e-34 116.7 0.9 3.1e-27 94.8 0.0 2.8 2 0 0 2 2 2 2 ZU5 domain Death PF00531.22 CDJ92148.1 - 9.1e-15 54.6 0.0 2.3e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Death domain Metallophos PF00149.28 CDJ92149.1 - 1.5e-28 100.7 0.1 1.9e-28 100.4 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDJ92149.1 - 0.0045 17.4 0.4 0.015 15.7 0.4 1.9 1 1 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 CDJ92149.1 - 0.053 13.2 0.0 0.078 12.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain 23S_rRNA_IVP PF05635.11 CDJ92149.1 - 0.14 12.5 1.1 0.23 11.8 1.1 1.4 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein Sema PF01403.19 CDJ92150.1 - 3.1e-45 154.7 0.1 4.8e-45 154.2 0.1 1.3 1 0 0 1 1 1 1 Sema domain TIG PF01833.24 CDJ92150.1 - 2.3e-30 104.5 0.1 4.5e-08 33.1 0.0 5.5 5 0 0 5 5 5 4 IPT/TIG domain TIG_plexin PF17960.1 CDJ92150.1 - 3.9e-24 84.5 0.1 5.8e-20 71.1 0.0 3.3 2 0 0 2 2 2 2 TIG domain TIG_2 PF18020.1 CDJ92150.1 - 5.5e-21 75.0 0.0 4.2e-20 72.2 0.0 2.5 2 0 0 2 2 2 1 TIG domain found in plexin PSI PF01437.25 CDJ92150.1 - 1.5e-17 63.8 49.5 3.9e-07 30.5 10.3 3.7 3 0 0 3 3 3 3 Plexin repeat Plexin_cytopl PF08337.12 CDJ92150.1 - 2.3e-08 33.2 0.0 3.1e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TMEM51 PF15345.6 CDJ92150.1 - 0.0042 17.0 0.1 0.0084 16.0 0.1 1.4 1 0 0 1 1 1 1 Transmembrane protein 51 AJAP1_PANP_C PF15298.6 CDJ92150.1 - 0.059 13.6 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Qn_am_d_aIII PF09099.10 CDJ92150.1 - 0.092 13.1 0.1 27 5.3 0.0 3.2 3 0 0 3 3 3 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III DUF1180 PF06679.12 CDJ92150.1 - 0.15 12.5 0.2 0.29 11.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) LapA_dom PF06305.11 CDJ92150.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain G-alpha PF00503.20 CDJ92151.1 - 1.6e-125 419.0 1.8 1.9e-125 418.8 1.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDJ92151.1 - 5.4e-18 65.0 0.1 3.4e-13 49.4 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ92151.1 - 3.3e-05 23.3 1.9 0.0062 15.9 0.5 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 CDJ92151.1 - 0.00041 20.6 0.4 1.1 9.5 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 CDJ92151.1 - 0.0068 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein Fam20C PF06702.12 CDJ92151.1 - 0.04 13.8 0.1 0.068 13.0 0.1 1.3 1 0 0 1 1 1 0 Golgi casein kinase, C-terminal, Fam20 FtsK_SpoIIIE PF01580.18 CDJ92151.1 - 0.088 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Ras PF00071.22 CDJ92151.1 - 0.11 12.1 0.5 9.4 5.8 0.2 2.4 2 0 0 2 2 2 0 Ras family MMR_HSR1 PF01926.23 CDJ92151.1 - 0.12 12.5 0.0 4.2 7.5 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 CDJ92151.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pox_A12 PF04651.13 CDJ92152.1 - 0.11 12.6 0.1 0.14 12.2 0.1 1.1 1 0 0 1 1 1 0 Poxvirus A12 protein CTV_P6 PF06706.11 CDJ92152.1 - 0.14 11.9 0.1 0.21 11.3 0.1 1.2 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein ShK PF01549.24 CDJ92153.1 - 0.00049 20.6 19.7 0.00064 20.2 2.6 2.8 2 1 0 2 2 2 2 ShK domain-like U-box PF04564.15 CDJ92154.1 - 1.7e-26 92.2 0.0 3.1e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 U-box domain CHIP_TPR_N PF18391.1 CDJ92154.1 - 3.3e-25 88.7 9.3 5.9e-25 87.8 9.3 1.4 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_1 PF00515.28 CDJ92154.1 - 6.5e-16 57.4 4.5 1e-05 25.2 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ92154.1 - 7.2e-15 53.8 3.4 0.00012 21.9 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ92154.1 - 2.7e-10 40.3 1.8 8.7e-10 38.7 1.9 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CDJ92154.1 - 2.2e-08 34.6 0.1 0.00021 21.9 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ92154.1 - 1.3e-07 31.2 7.7 9.4e-06 25.2 0.2 3.3 2 1 1 3 3 3 1 TPR repeat TPR_8 PF13181.6 CDJ92154.1 - 7e-07 29.0 2.6 0.011 15.9 0.3 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ92154.1 - 2.3e-06 28.0 0.3 0.01 16.3 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ92154.1 - 7e-05 23.1 2.9 0.83 10.0 0.0 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ92154.1 - 0.00011 22.0 0.6 0.79 9.9 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ92154.1 - 0.0018 19.0 0.0 1.1 10.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-NOSIP PF15906.5 CDJ92154.1 - 0.0026 17.8 0.0 0.0053 16.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein TPR_9 PF13371.6 CDJ92154.1 - 0.0034 17.5 0.3 0.15 12.2 0.0 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_3 PF07720.12 CDJ92154.1 - 0.0042 17.1 1.0 0.027 14.5 0.5 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ92154.1 - 0.033 14.1 1.0 1.2 9.1 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 CDJ92154.1 - 0.033 14.3 0.5 2 8.6 0.1 2.8 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Pex26 PF07163.12 CDJ92154.1 - 0.054 12.8 0.4 0.078 12.3 0.4 1.2 1 0 0 1 1 1 0 Pex26 protein HrpB1_HrpK PF09613.10 CDJ92154.1 - 0.088 12.4 0.1 5.2 6.7 0.0 2.3 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) Laps PF10169.9 CDJ92154.1 - 0.17 12.5 2.4 0.3 11.7 2.4 1.3 1 0 0 1 1 1 0 Learning-associated protein TPR_6 PF13174.6 CDJ92154.1 - 0.5 11.1 6.8 3.5 8.5 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat zf-CCCH_2 PF14608.6 CDJ92155.1 - 9.1e-13 48.2 57.3 0.00012 22.4 4.2 5.6 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger PWI PF01480.17 CDJ92155.1 - 1.5e-05 25.2 0.9 3e-05 24.3 0.9 1.5 1 0 0 1 1 1 1 PWI domain His_Phos_1 PF00300.22 CDJ92156.1 - 6.8e-10 38.9 0.0 1.7e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3774 PF12609.8 CDJ92156.1 - 2.9 8.9 0.0 2.9 8.9 0.0 4.3 3 2 0 3 3 3 0 Wound-induced protein Vps39_2 PF10367.9 CDJ92157.1 - 0.00084 19.8 0.4 0.00084 19.8 0.4 1.6 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.6 CDJ92157.1 - 0.0039 17.1 5.6 0.0076 16.2 5.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CDJ92157.1 - 0.026 14.9 6.6 0.055 13.8 6.6 1.6 1 0 0 1 1 1 0 Ring finger domain Zn_ribbon_17 PF17120.5 CDJ92157.1 - 0.038 13.6 3.4 0.077 12.6 3.4 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CDJ92157.1 - 0.051 13.4 6.8 0.13 12.1 6.3 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 CDJ92157.1 - 0.083 12.6 3.2 0.27 11.0 3.2 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4 PF00097.25 CDJ92157.1 - 0.25 11.2 6.9 0.84 9.6 6.6 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ92157.1 - 1.8 8.5 8.8 8.3 6.4 9.1 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3716 PF12511.8 CDJ92157.1 - 3.4 7.8 7.3 11 6.2 5.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3716) Cytochrom_C_2 PF01322.20 CDJ92158.1 - 0.018 16.0 0.4 0.06 14.2 0.2 1.8 1 1 0 2 2 2 0 Cytochrome C' CNOT1_TTP_bind PF16417.5 CDJ92158.1 - 0.062 12.5 0.1 0.09 11.9 0.1 1.4 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain Exo_endo_phos_2 PF14529.6 CDJ92159.1 - 1.4e-07 31.3 0.0 2.7e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 CDJ92160.1 - 2.8e-33 115.3 0.0 2.1e-16 60.1 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Apc15p PF05841.11 CDJ92161.1 - 0.035 14.9 3.4 0.052 14.3 3.4 1.2 1 0 0 1 1 1 0 Apc15p protein Baculo_11_kDa PF06143.11 CDJ92161.1 - 0.048 13.2 1.5 0.064 12.8 0.4 1.7 2 0 0 2 2 2 0 Baculovirus 11 kDa family PepSY_TM PF03929.16 CDJ92161.1 - 0.067 12.8 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 PepSY-associated TM region Orf78 PF06024.12 CDJ92161.1 - 0.11 12.9 1.3 1.3 9.3 0.0 2.2 2 0 0 2 2 2 0 Orf78 (ac78) TraL PF07178.11 CDJ92161.1 - 0.11 13.0 0.5 0.21 12.1 0.5 1.4 1 0 0 1 1 1 0 TraL protein LD_cluster2 PF18163.1 CDJ92161.1 - 0.41 10.1 3.2 0.6 9.6 3.2 1.2 1 0 0 1 1 1 0 SLOG cluster2 S_4TM PF18159.1 CDJ92161.1 - 0.88 8.8 3.2 1.4 8.1 0.1 2.0 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain EphA2_TM PF14575.6 CDJ92161.1 - 3.3 8.7 5.8 0.91 10.4 0.5 2.3 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain CUB PF00431.20 CDJ92162.1 - 1.6e-06 28.5 0.1 6.2e-06 26.5 0.0 2.0 2 1 0 2 2 2 1 CUB domain DUF1459 PF07312.11 CDJ92163.1 - 0.22 11.8 9.7 0.28 11.4 9.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1459) PsbN PF02468.15 CDJ92163.1 - 0.5 10.2 2.7 0.84 9.5 0.3 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) Trnau1ap PF17654.1 CDJ92163.1 - 9.1 7.2 16.6 14 6.7 16.6 1.3 1 0 0 1 1 1 0 Selenocysteine tRNA 1 associated proteins CUB PF00431.20 CDJ92166.1 - 6.3e-162 528.6 6.3 4.6e-28 97.7 0.0 19.1 18 1 1 19 19 19 18 CUB domain EGF_CA PF07645.15 CDJ92166.1 - 1.2e-09 38.2 17.8 1.4e-06 28.4 3.8 8.0 4 1 3 7 7 7 3 Calcium-binding EGF domain EGF PF00008.27 CDJ92166.1 - 2.8e-09 37.1 97.5 0.0032 17.8 9.5 8.0 7 0 0 7 7 7 5 EGF-like domain CUB_2 PF02408.20 CDJ92166.1 - 1.6e-06 27.9 10.5 4.8 7.0 0.0 9.5 10 0 0 10 10 10 1 CUB-like domain cEGF PF12662.7 CDJ92166.1 - 0.00095 19.0 15.4 0.0019 18.1 2.4 8.9 9 0 0 9 9 9 3 Complement Clr-like EGF-like EGF_3 PF12947.7 CDJ92166.1 - 0.0015 18.7 3.4 0.0015 18.7 3.4 8.1 7 0 0 7 7 7 3 EGF domain hEGF PF12661.7 CDJ92166.1 - 0.033 14.8 72.9 0.083 13.6 5.4 8.5 7 0 0 7 7 7 0 Human growth factor-like EGF Cytochrom_C PF00034.21 CDJ92167.1 - 5.4e-10 40.3 0.0 8.7e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CDJ92167.1 - 3.3e-06 27.3 0.1 9.8e-06 25.8 0.1 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 CDJ92167.1 - 9.4e-06 25.4 0.2 5.2e-05 23.0 0.1 1.9 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrome-c551 PF10643.9 CDJ92167.1 - 0.03 13.9 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Cytochrom_C PF00034.21 CDJ92168.1 - 2.5e-10 41.4 0.0 3.6e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CDJ92168.1 - 2.2e-06 27.9 0.1 1.2e-05 25.5 0.1 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 CDJ92168.1 - 0.00039 20.1 0.1 0.0033 17.1 0.0 2.0 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrome-c551 PF10643.9 CDJ92168.1 - 0.0096 15.5 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Photosystem P840 reaction-centre cytochrome c-551 Y_phosphatase PF00102.27 CDJ92170.1 - 6.4e-57 192.8 0.1 9e-57 192.3 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ92170.1 - 0.00094 19.0 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Myb_DNA-binding PF00249.31 CDJ92171.1 - 2.2e-13 50.1 0.0 4.7e-06 26.7 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain ELM2 PF01448.24 CDJ92171.1 - 4.9e-07 30.4 0.4 4.9e-07 30.4 0.4 2.7 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-bind_7 PF15963.5 CDJ92171.1 - 1.4e-06 28.1 11.1 0.0017 18.2 0.1 3.6 3 0 0 3 3 3 2 Myb DNA-binding like RasGAP_C PF03836.15 CDJ92171.1 - 0.011 15.8 13.8 0.019 15.1 12.4 2.2 1 1 0 1 1 1 0 RasGAP C-terminus Myb_DNA-bind_6 PF13921.6 CDJ92171.1 - 0.014 15.6 0.1 2.2 8.6 0.0 2.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF4279 PF14106.6 CDJ92171.1 - 0.48 10.7 6.8 1.3 9.3 0.5 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4279) Exo_endo_phos PF03372.23 CDJ92172.1 - 0.00045 19.8 0.0 0.0011 18.6 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CDJ92172.1 - 0.027 14.3 0.0 0.07 13.0 0.0 1.7 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Kinesin PF00225.23 CDJ92173.1 - 1.5e-41 142.4 0.1 1.5e-30 106.3 0.0 2.2 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CDJ92173.1 - 3.6e-40 137.3 0.0 6.5e-40 136.5 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Phage_GPL PF05926.11 CDJ92173.1 - 0.39 10.7 1.6 0.52 10.3 0.2 1.8 2 0 0 2 2 2 0 Phage head completion protein (GPL) Spectrin PF00435.21 CDJ92175.1 - 0 1295.6 328.2 3.6e-20 72.4 0.3 30.9 31 0 0 31 31 31 30 Spectrin repeat CH PF00307.31 CDJ92175.1 - 4e-45 152.5 7.2 6.1e-24 84.3 0.1 4.8 4 0 0 4 4 4 2 Calponin homology (CH) domain PH_9 PF15410.6 CDJ92175.1 - 2e-13 50.7 0.0 1.3e-12 48.1 0.0 2.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 CDJ92175.1 - 1.1e-06 29.1 0.6 3.4e-06 27.5 0.0 2.2 2 0 0 2 2 1 1 PH domain SH3_9 PF14604.6 CDJ92175.1 - 1.1e-05 25.2 0.1 3.3e-05 23.7 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain CAMSAP_CH PF11971.8 CDJ92175.1 - 1.7e-05 24.6 0.0 0.00042 20.1 0.0 2.9 2 0 0 2 2 2 1 CAMSAP CH domain SH3_1 PF00018.28 CDJ92175.1 - 4.5e-05 23.0 0.0 0.00021 20.8 0.0 2.2 1 0 0 1 1 1 1 SH3 domain SH3_10 PF17902.1 CDJ92175.1 - 0.00031 20.8 0.0 0.00094 19.2 0.0 1.8 1 0 0 1 1 1 1 SH3 domain CH_2 PF06294.11 CDJ92175.1 - 0.0016 18.5 0.1 2.4 8.4 0.0 4.0 2 0 0 2 2 2 1 CH-like domain in sperm protein SH3_3 PF08239.11 CDJ92175.1 - 0.017 15.4 0.0 0.047 14.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain ABC_trans_N PF14510.6 CDJ92175.1 - 1.9 9.1 4.1 72 4.1 0.2 4.8 3 0 0 3 3 2 0 ABC-transporter N-terminal Lentiviral_Tat PF02998.14 CDJ92175.1 - 3.6 7.7 7.8 2.6 8.2 0.0 4.8 3 0 0 3 3 3 0 Lentiviral Tat protein Kunitz_BPTI PF00014.23 CDJ92176.1 - 5.4e-14 52.2 7.3 1e-13 51.3 7.3 1.4 1 1 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Ost5 PF05251.12 CDJ92177.1 - 1.2e-28 99.2 2.1 1.3e-28 99.0 2.1 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 DHHC PF01529.20 CDJ92177.1 - 0.18 11.9 1.1 0.2 11.7 1.1 1.0 1 0 0 1 1 1 0 DHHC palmitoyltransferase Serinc PF03348.15 CDJ92178.1 - 1.1e-164 548.5 19.1 1.2e-164 548.3 19.1 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Frag1 PF10277.9 CDJ92179.1 - 0.00088 18.9 7.8 0.0012 18.5 7.8 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Glyco_hydro_8 PF01270.17 CDJ92179.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 8 ABC2_membrane_5 PF13346.6 CDJ92179.1 - 0.15 11.6 6.7 0.19 11.3 6.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Nuc_sug_transp PF04142.15 CDJ92181.1 - 2e-106 355.7 16.4 2.3e-106 355.5 16.4 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 CDJ92181.1 - 4.4e-07 29.4 2.7 4.4e-07 29.4 2.7 2.0 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 CDJ92181.1 - 1.5e-05 25.2 28.0 0.0014 18.8 6.7 2.8 2 1 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 CDJ92181.1 - 0.00027 20.0 1.1 0.00027 20.0 1.1 2.1 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 CDJ92181.1 - 0.00042 19.6 15.2 0.00086 18.6 13.8 2.1 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.6 CDJ92181.1 - 0.00058 19.5 0.4 0.00058 19.5 0.4 2.6 3 0 0 3 3 3 1 Putative multidrug resistance efflux transporter DUF4131 PF13567.6 CDJ92181.1 - 7.6 6.2 7.3 0.44 10.2 0.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) MH2 PF03166.14 CDJ92182.1 - 2e-61 207.5 0.3 3.1e-61 206.8 0.3 1.3 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 CDJ92182.1 - 1.8e-39 134.1 4.2 3.5e-39 133.2 1.9 2.2 2 0 0 2 2 2 1 MH1 domain CLASP_N PF12348.8 CDJ92183.1 - 3.9e-32 111.7 1.1 3.9e-32 111.7 1.1 3.2 3 0 0 3 3 3 1 CLASP N terminal DUF5071 PF16804.5 CDJ92183.1 - 0.0005 20.3 0.4 0.16 12.2 0.0 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF5071) TAN PF11640.8 CDJ92183.1 - 0.0018 18.4 0.9 0.01 16.0 0.1 2.8 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair Tti2 PF10521.9 CDJ92183.1 - 0.0065 16.1 1.3 0.59 9.6 0.4 3.0 3 0 0 3 3 3 1 Tti2 family HEAT PF02985.22 CDJ92183.1 - 0.01 16.0 7.8 0.99 9.8 0.0 5.5 6 0 0 6 6 5 0 HEAT repeat MMS19_N PF14500.6 CDJ92183.1 - 0.016 14.8 6.1 0.9 9.1 0.2 4.5 4 2 0 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II RTP1_C1 PF10363.9 CDJ92183.1 - 0.02 15.1 1.6 9.1 6.5 0.0 4.6 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 GEP5 PF17053.5 CDJ92183.1 - 0.048 13.5 1.7 0.22 11.4 0.1 2.7 3 1 0 3 3 3 0 Genetic interactor of prohibitin 5 V-ATPase_H_N PF03224.14 CDJ92183.1 - 0.099 11.9 3.4 0.18 11.1 1.1 2.4 2 0 0 2 2 2 0 V-ATPase subunit H DUF2785 PF10978.8 CDJ92183.1 - 0.23 11.2 1.5 11 5.7 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2785) Cnd1 PF12717.7 CDJ92183.1 - 2.5 8.1 6.1 1.1e+02 2.7 0.0 4.5 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CDJ92184.1 - 2.1e-10 39.9 0.5 1.1e-05 25.2 0.1 3.6 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 CDJ92184.1 - 3.3e-06 27.5 0.5 0.0046 17.4 0.0 2.7 2 0 0 2 2 2 2 HEAT-like repeat CLASP_N PF12348.8 CDJ92184.1 - 4.9e-06 26.3 0.0 7.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 CLASP N terminal Arm PF00514.23 CDJ92184.1 - 1.7e-05 24.7 0.0 0.0056 16.7 0.0 2.8 1 1 1 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CDJ92184.1 - 3.7e-05 24.0 0.2 0.0098 16.3 0.0 2.7 2 1 0 2 2 2 1 HEAT repeats Cnd1 PF12717.7 CDJ92184.1 - 0.00086 19.4 0.0 0.41 10.7 0.0 2.2 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CDJ92184.1 - 0.0031 18.1 0.0 0.36 11.5 0.0 2.5 1 1 1 2 2 2 1 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.7 CDJ92184.1 - 0.0037 17.5 0.0 0.31 11.4 0.0 2.6 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.20 CDJ92184.1 - 0.026 13.1 0.2 0.034 12.7 0.2 1.2 1 0 0 1 1 1 0 Adaptin N terminal region Tti2 PF10521.9 CDJ92184.1 - 0.061 12.8 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 Tti2 family IFRD PF05004.13 CDJ92184.1 - 0.085 11.9 0.1 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) MBT PF02820.18 CDJ92186.1 - 5.2e-25 87.6 0.0 3.9e-15 56.0 0.0 2.4 2 0 0 2 2 2 2 mbt repeat ProQ_C PF17516.2 CDJ92186.1 - 0.2 11.1 0.0 0.49 9.9 0.0 1.6 1 0 0 1 1 1 0 ProQ C-terminal domain HOCHOB PF17943.1 CDJ92187.1 - 0.008 16.9 0.3 0.085 13.6 0.0 2.3 2 1 1 3 3 3 1 Homeobox-cysteine loop-homeobox Peptidase_S64 PF08192.11 CDJ92187.1 - 0.58 8.6 10.1 0.75 8.2 10.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF681 PF05080.12 CDJ92189.1 - 0.0094 16.6 0.1 0.028 15.1 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF681) PROCN PF08083.11 CDJ92189.1 - 0.12 11.1 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 PROCN (NUC071) domain Peptidase_M1 PF01433.20 CDJ92190.1 - 1.5e-63 214.3 0.4 1.7e-63 214.1 0.4 1.0 1 0 0 1 1 1 1 Peptidase family M1 domain DUF1570 PF07607.11 CDJ92190.1 - 0.041 14.2 0.2 0.084 13.2 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1570) Peptidase_M61 PF05299.12 CDJ92190.1 - 0.041 14.3 1.6 4 7.8 1.6 2.5 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Peptidase_M1 PF01433.20 CDJ92191.1 - 1.5e-63 214.3 0.4 1.7e-63 214.1 0.4 1.0 1 0 0 1 1 1 1 Peptidase family M1 domain DUF1570 PF07607.11 CDJ92191.1 - 0.041 14.2 0.2 0.084 13.2 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1570) Peptidase_M61 PF05299.12 CDJ92191.1 - 0.041 14.3 1.6 4 7.8 1.6 2.5 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Cadherin PF00028.17 CDJ92192.1 - 7.1e-12 45.6 0.6 1.1e-06 29.0 0.0 3.8 3 2 1 4 4 4 2 Cadherin domain Cadherin_pro PF08758.11 CDJ92192.1 - 0.012 15.8 0.0 1.4 9.1 0.0 2.8 2 0 0 2 2 2 0 Cadherin prodomain like DUF1218 PF06749.12 CDJ92193.1 - 0.014 15.9 0.1 0.032 14.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1218) Astacin PF01400.24 CDJ92195.1 - 5.8e-53 179.4 0.2 1.2e-52 178.3 0.2 1.5 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 CDJ92195.1 - 0.00021 21.0 0.1 0.00027 20.7 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CDJ92195.1 - 0.00035 20.5 0.8 0.0017 18.2 0.7 1.9 1 1 1 2 2 2 1 Matrixin Reprolysin_3 PF13582.6 CDJ92195.1 - 0.0073 16.8 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 CDJ92195.1 - 0.0091 15.2 0.3 0.015 14.5 0.3 1.3 1 0 0 1 1 1 1 Met-zincin Reprolysin_5 PF13688.6 CDJ92195.1 - 0.017 15.3 0.1 0.027 14.6 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 CDJ92195.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.13 CDJ92195.1 - 0.78 10.2 8.7 2.4 8.6 8.7 1.9 1 1 0 1 1 1 0 EGF-like domain CAP PF00188.26 CDJ92196.1 - 2.1e-34 119.1 16.0 3.7e-19 69.8 4.7 2.4 2 0 0 2 2 2 2 Cysteine-rich secretory protein family SH2 PF00017.24 CDJ92197.1 - 2e-11 43.8 0.2 4.1e-11 42.8 0.2 1.6 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.16 CDJ92197.1 - 1.8e-08 34.6 0.0 3.7e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 SOCS box Nop16 PF09420.10 CDJ92198.1 - 8.3e-20 71.7 12.7 3.8e-15 56.5 2.1 2.0 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 G-alpha PF00503.20 CDJ92199.1 - 8.9e-106 354.0 6.7 1.2e-105 353.6 6.7 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDJ92199.1 - 3.4e-11 42.9 1.4 1.2e-10 41.1 0.7 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family ALS2CR8 PF15299.6 CDJ92199.1 - 0.016 15.1 0.0 0.044 13.7 0.0 1.6 1 1 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Inhibitor_I53 PF11714.8 CDJ92199.1 - 0.17 12.1 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 Thrombin inhibitor Madanin Galactosyl_T PF01762.21 CDJ92200.1 - 2e-41 142.0 0.0 2.6e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase CAP PF00188.26 CDJ92201.1 - 3.1e-36 125.0 10.6 1.5e-18 67.9 4.5 2.3 2 0 0 2 2 2 2 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ92201.1 - 0.00026 21.3 3.7 0.15 12.3 0.1 3.3 2 1 0 2 2 2 2 Ancylostoma-associated secreted protein related RPN5_C PF18098.1 CDJ92201.1 - 0.0069 16.5 0.1 0.015 15.4 0.1 1.6 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain ATP-synt_F6 PF05511.11 CDJ92201.1 - 0.036 14.5 0.0 3.4 8.1 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 Metallothio_PEC PF02068.16 CDJ92201.1 - 0.76 10.2 27.3 3.3 8.1 10.3 2.6 2 0 0 2 2 2 0 Plant PEC family metallothionein Metallothio_Euk PF12749.7 CDJ92201.1 - 2.4 8.4 25.4 1.9 8.7 6.8 3.1 2 1 0 2 2 2 0 Eukaryotic metallothionein ASPRs PF17641.2 CDJ92202.1 - 0.0013 19.0 0.1 0.0043 17.3 0.1 1.8 1 1 0 1 1 1 1 Ancylostoma-associated secreted protein related RVT_1 PF00078.27 CDJ92203.1 - 9.9e-14 51.4 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Metallophos PF00149.28 CDJ92204.1 - 1.9e-17 64.4 5.8 3.3e-17 63.7 5.8 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 CDJ92204.1 - 4.4e-17 62.7 2.6 9.1e-17 61.7 0.0 2.6 2 1 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 CDJ92204.1 - 2.6e-10 40.7 1.1 5.3e-10 39.7 1.1 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 CDJ92204.1 - 0.028 15.0 0.2 0.088 13.4 0.1 1.9 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain DUF4489 PF14879.6 CDJ92205.1 - 0.79 9.8 7.1 1.3 9.1 7.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4489) PLAT PF01477.23 CDJ92206.1 - 1.9e-16 60.6 0.1 2.5e-16 60.3 0.1 1.1 1 0 0 1 1 1 1 PLAT/LH2 domain Moulting_cycle PF04870.16 CDJ92207.1 - 2.7e-62 211.1 7.5 3.9e-62 210.6 7.5 1.1 1 0 0 1 1 1 1 Moulting cycle TFR_dimer PF04253.15 CDJ92207.1 - 0.021 15.0 1.3 0.037 14.1 1.3 1.5 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain TMPIT PF07851.13 CDJ92207.1 - 7 5.8 6.4 9.5 5.4 6.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein Vinculin PF01044.19 CDJ92208.1 - 3.7e-55 187.7 1.0 4.4e-55 187.4 1.0 1.1 1 0 0 1 1 1 1 Vinculin family Dymeclin PF09742.9 CDJ92208.1 - 0.056 11.9 0.3 0.12 10.8 0.1 1.6 2 0 0 2 2 2 0 Dyggve-Melchior-Clausen syndrome protein DUF4335 PF14233.6 CDJ92208.1 - 0.061 13.2 0.0 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4335) Rab5ip PF07019.12 CDJ92209.1 - 5e-16 59.0 8.0 6.5e-16 58.7 8.0 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Ldl_recept_a PF00057.18 CDJ92211.1 - 8.1e-15 54.8 14.0 1.1e-07 31.9 3.7 2.2 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A Guanylate_cyc PF00211.20 CDJ92212.1 - 1.2e-55 188.0 0.1 1.8e-55 187.4 0.1 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF1053 PF06327.14 CDJ92212.1 - 0.0079 16.7 0.0 0.021 15.4 0.0 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) AC_N PF16214.5 CDJ92212.1 - 3.2 6.8 12.3 1 8.4 0.0 3.4 3 1 0 3 3 3 0 Adenylyl cyclase N-terminal extracellular and transmembrane region TSP_1 PF00090.19 CDJ92213.1 - 1.3e-64 214.2 155.7 6.4e-10 39.1 10.4 10.3 10 0 0 10 10 10 10 Thrombospondin type 1 domain Clc-like PF07062.12 CDJ92214.1 - 1e-91 306.2 6.7 1.2e-91 305.9 6.7 1.0 1 0 0 1 1 1 1 Clc-like Claudin_3 PF06653.11 CDJ92214.1 - 0.00056 19.9 8.9 0.19 11.7 0.1 2.3 2 0 0 2 2 2 2 Tight junction protein, Claudin-like SUR7 PF06687.12 CDJ92214.1 - 0.82 9.3 13.9 19 4.8 0.3 2.3 1 1 1 2 2 2 0 SUR7/PalI family DUF2721 PF11026.8 CDJ92214.1 - 1.1 9.1 10.1 0.079 12.9 1.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) 7tm_1 PF00001.21 CDJ92216.1 - 2.3e-23 82.9 21.3 2.9e-23 82.5 21.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDJ92216.1 - 8.9e-18 64.6 27.8 3.1e-17 62.8 27.8 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 CDJ92216.1 - 4.4e-09 36.1 25.4 6e-09 35.7 25.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 CDJ92216.1 - 0.00032 20.4 22.6 0.00038 20.2 21.7 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF962 PF06127.11 CDJ92216.1 - 0.0086 16.1 0.2 0.046 13.8 0.2 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF2116 PF09889.9 CDJ92216.1 - 0.47 10.5 2.7 1.6 8.7 0.2 2.7 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) BTB PF00651.31 CDJ92218.1 - 4.5e-25 88.0 0.5 8.4e-25 87.2 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 CDJ92218.1 - 1.7e-19 69.8 2.2 4.9e-19 68.3 1.1 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 CDJ92218.1 - 1.8e-16 60.4 0.1 1.7e-08 34.6 0.0 2.2 2 0 0 2 2 2 2 F5/8 type C domain BTB PF00651.31 CDJ92219.1 - 2e-26 92.4 0.2 2.5e-24 85.7 0.0 2.6 2 1 1 3 3 3 2 BTB/POZ domain BACK PF07707.15 CDJ92219.1 - 8.5e-19 67.6 1.3 6.2e-18 64.8 0.6 2.3 3 0 0 3 3 3 1 BTB And C-terminal Kelch BTB PF00651.31 CDJ92221.1 - 9.4e-24 83.8 0.2 1.7e-23 83.0 0.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 CDJ92221.1 - 4.8e-11 42.7 1.7 4.7e-10 39.5 0.5 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch DUF2087 PF09860.9 CDJ92221.1 - 0.042 14.0 0.1 0.099 12.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) DUF3106 PF11304.8 CDJ92224.1 - 0.14 12.6 1.8 0.48 10.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) GCV_T PF01571.21 CDJ92225.1 - 2.4e-52 177.9 0.0 3.2e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 CDJ92225.1 - 1.7e-38 133.2 0.0 2.8e-38 132.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T_C PF08669.11 CDJ92225.1 - 1.1e-09 38.1 0.0 2.9e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 CDJ92225.1 - 1.3e-06 28.7 0.4 2.9e-06 27.5 0.4 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain SoxG PF04268.12 CDJ92225.1 - 0.062 13.5 0.0 0.24 11.6 0.0 1.9 2 0 0 2 2 2 0 Sarcosine oxidase, gamma subunit family Kelch_1 PF01344.25 CDJ92226.1 - 1.2e-65 216.8 13.1 1.4e-14 53.4 0.1 6.0 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 CDJ92226.1 - 2.1e-43 145.2 3.0 9.6e-08 32.1 0.0 5.9 1 1 5 6 6 6 5 Kelch motif Kelch_2 PF07646.15 CDJ92226.1 - 1.1e-31 107.6 12.6 3.8e-07 29.8 0.4 6.2 5 1 1 6 6 6 5 Kelch motif Kelch_4 PF13418.6 CDJ92226.1 - 7.2e-21 73.9 8.4 0.0004 20.3 0.1 5.7 5 2 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ92226.1 - 1.1e-16 60.6 8.9 0.00082 19.6 0.1 5.5 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ92226.1 - 3.9e-11 42.7 9.8 0.13 12.3 0.1 5.2 5 0 0 5 5 5 4 Kelch motif Glu_cyclase_2 PF05096.12 CDJ92226.1 - 0.00021 20.8 0.0 0.068 12.6 0.0 2.6 1 1 1 2 2 2 2 Glutamine cyclotransferase Glyoxal_oxid_N PF07250.11 CDJ92226.1 - 0.00029 20.1 0.6 1.5 7.9 0.1 3.5 1 1 3 4 4 4 2 Glyoxal oxidase N-terminus PQQ_3 PF13570.6 CDJ92226.1 - 0.018 15.5 10.2 22 5.7 0.1 5.2 5 0 0 5 5 5 0 PQQ-like domain AFP_2 PF18815.1 CDJ92226.1 - 0.022 15.0 0.0 9.4 6.6 0.0 3.4 4 0 0 4 4 4 0 Bacterial antifreeze protein repeat BACK PF07707.15 CDJ92227.1 - 5.5e-34 116.4 2.3 1.1e-33 115.4 0.3 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 CDJ92227.1 - 8.4e-29 100.0 0.8 1.3e-28 99.4 0.3 1.7 2 0 0 2 2 2 1 BTB/POZ domain FANC_SAP PF18081.1 CDJ92227.1 - 0.18 12.0 0.7 0.38 11.0 0.1 1.9 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain TGF_beta PF00019.20 CDJ92228.1 - 0.0017 19.3 0.3 0.0034 18.3 0.1 1.6 2 0 0 2 2 2 1 Transforming growth factor beta like domain SSrecog PF03531.14 CDJ92231.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Structure-specific recognition protein (SSRP1) Sulfotransfer_1 PF00685.27 CDJ92234.1 - 2.8e-33 115.5 0.0 3.5e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CDJ92234.1 - 1.4e-14 55.1 0.1 1.1e-09 39.0 0.1 3.0 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 CDJ92234.1 - 0.019 14.9 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 Sulfotransferase family efThoc1 PF11957.8 CDJ92234.1 - 0.092 11.4 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor Ion_trans PF00520.31 CDJ92236.1 - 5.2e-41 140.5 13.5 7.2e-41 140.0 13.5 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 CDJ92236.1 - 4e-28 97.6 0.5 1.2e-27 96.1 0.1 2.1 2 0 0 2 2 2 1 BTB/POZ domain Shal-type PF11601.8 CDJ92236.1 - 3.5e-15 55.2 11.6 6e-15 54.5 11.6 1.4 1 0 0 1 1 1 1 Shal-type voltage-gated potassium channels, N-terminal DUF3399 PF11879.8 CDJ92236.1 - 2.5e-13 50.3 1.2 2.5e-13 50.3 1.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3399) Ion_trans_2 PF07885.16 CDJ92236.1 - 7.6e-13 48.2 5.3 7.6e-13 48.2 5.3 2.3 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 CDJ92236.1 - 0.0011 19.1 0.0 0.003 17.6 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Cytochrom_B_C PF00032.17 CDJ92236.1 - 0.036 14.4 1.9 0.086 13.1 1.2 2.0 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD COX2-transmemb PF09125.10 CDJ92236.1 - 0.32 10.8 4.4 1 9.2 2.4 2.7 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane PKD_channel PF08016.12 CDJ92236.1 - 0.48 9.0 8.2 0.83 8.3 8.2 1.4 1 1 0 1 1 1 0 Polycystin cation channel DB PF01682.19 CDJ92237.1 - 2.2e-15 56.8 8.3 3.2e-15 56.2 8.3 1.2 1 0 0 1 1 1 1 DB module Mucin PF01456.17 CDJ92238.1 - 0.13 12.3 14.1 0.27 11.2 14.1 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein RT_RNaseH_2 PF17919.1 CDJ92239.1 - 1.7e-27 95.3 0.0 9.7e-27 92.9 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ92239.1 - 7.3e-27 93.9 0.0 9.7e-25 87.1 0.0 3.3 3 0 0 3 3 3 1 Integrase core domain RVT_1 PF00078.27 CDJ92239.1 - 1.6e-21 76.9 0.0 3.2e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ92239.1 - 2e-17 63.1 0.0 4.8e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 CDJ92239.1 - 1.7e-14 54.0 0.0 6.8e-14 52.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 CDJ92239.1 - 3.3e-07 30.8 0.0 7.4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ92239.1 - 3.3e-06 27.6 0.0 1.2e-05 25.8 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease rve_3 PF13683.6 CDJ92239.1 - 8e-06 25.5 0.1 0.00015 21.5 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 CDJ92239.1 - 0.0005 20.2 0.0 0.0015 18.7 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger RTBV_P12 PF06361.11 CDJ92239.1 - 0.0052 17.2 0.3 6.1 7.3 0.1 2.5 2 0 0 2 2 2 2 Rice tungro bacilliform virus P12 protein RVP PF00077.20 CDJ92239.1 - 0.0056 17.0 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF3567 PF12091.8 CDJ92239.1 - 0.022 14.9 0.0 16 5.7 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3567) DUF2293 PF10056.9 CDJ92239.1 - 0.051 13.8 0.1 0.18 12.1 0.1 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2293) MVL PF12151.8 CDJ92240.1 - 0.028 14.3 1.1 0.058 13.3 1.1 1.5 1 0 0 1 1 1 0 Mannan-binding protein Sporozoite_P67 PF05642.11 CDJ92240.1 - 0.32 9.0 33.0 0.009 14.2 18.0 2.0 1 1 1 2 2 2 0 Sporozoite P67 surface antigen Solute_trans_a PF03619.16 CDJ92241.1 - 1.2e-23 84.0 19.0 1.5e-23 83.6 19.0 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha SAC3_GANP PF03399.16 CDJ92242.1 - 3.3e-30 105.5 3.8 8.7e-29 100.8 3.8 2.3 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 CDJ92242.1 - 4.5e-08 33.2 0.0 1.2e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SR-25 PF10500.9 CDJ92242.1 - 0.12 12.0 26.0 0.21 11.2 26.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HTH_36 PF13730.6 CDJ92242.1 - 0.13 12.2 0.0 16 5.5 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Nop53 PF07767.11 CDJ92242.1 - 0.14 11.5 19.8 0.26 10.6 19.8 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TAF1D PF15333.6 CDJ92242.1 - 0.22 11.2 14.3 0.41 10.4 14.3 1.4 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D BTB_2 PF02214.22 CDJ92243.1 - 7.9e-18 64.6 0.0 1.3e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF5096 PF17019.5 CDJ92245.1 - 0.04 13.7 0.1 0.04 13.7 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5096) DUF898 PF05987.13 CDJ92246.1 - 0.16 11.0 8.2 0.011 14.8 3.1 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) Sprouty PF05210.13 CDJ92246.1 - 0.49 10.8 0.1 0.49 10.8 0.1 2.1 3 0 0 3 3 3 0 Sprouty protein (Spry) DUF2721 PF11026.8 CDJ92246.1 - 4.2 7.3 13.0 2.1 8.2 7.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Peptidase_M2 PF01401.18 CDJ92248.1 - 1.2e-89 301.5 0.1 1.3e-89 301.4 0.1 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme EB PF01683.18 CDJ92248.1 - 0.00017 21.8 0.8 0.00025 21.3 0.1 1.6 2 0 0 2 2 2 1 EB module Ub-RnfH PF03658.14 CDJ92249.1 - 0.16 12.4 0.6 5 7.6 0.1 2.1 1 1 1 2 2 2 0 RnfH family Ubiquitin DDDD PF10161.9 CDJ92250.1 - 5.6e-12 45.3 0.0 7.4e-12 44.9 0.0 1.3 1 1 0 1 1 1 1 Putative mitochondrial precursor protein HU-CCDC81_bac_1 PF18174.1 CDJ92250.1 - 0.076 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 1 FBPase PF00316.20 CDJ92251.1 - 5.5e-77 257.5 0.1 7.3e-77 257.1 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 CDJ92251.1 - 0.006 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family Glu_dehyd_C PF16912.5 CDJ92251.1 - 0.16 11.4 0.1 0.28 10.6 0.1 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus FBPase PF00316.20 CDJ92252.1 - 4e-75 251.4 0.1 5.2e-75 251.1 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 CDJ92252.1 - 0.0014 18.2 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Inositol monophosphatase family SIKE PF05769.11 CDJ92253.1 - 1.3e-13 51.2 13.5 3.7e-13 49.8 13.5 1.6 1 1 0 1 1 1 1 SIKE family PIN_8 PF18476.1 CDJ92253.1 - 0.06 13.2 5.9 0.083 12.7 5.9 1.2 1 0 0 1 1 1 0 PIN like domain BAT PF15915.5 CDJ92253.1 - 0.063 13.2 0.2 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 GAF and HTH_10 associated domain bZIP_2 PF07716.15 CDJ92253.1 - 0.21 11.7 0.2 0.21 11.7 0.2 2.9 3 0 0 3 3 3 0 Basic region leucine zipper V_ATPase_I PF01496.19 CDJ92253.1 - 0.49 8.2 3.7 0.6 8.0 3.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1319 PF07028.11 CDJ92253.1 - 0.59 10.4 5.1 8.6 6.6 5.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) DUF5094 PF17015.5 CDJ92253.1 - 0.83 9.7 14.2 2.8 8.0 5.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5094) UPF0242 PF06785.11 CDJ92253.1 - 0.85 9.7 9.3 1.4 9.0 9.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HSCB_C PF07743.13 CDJ92253.1 - 1.6 9.3 14.1 1.9 9.0 7.8 3.2 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain TSC22 PF01166.18 CDJ92253.1 - 4.5 7.7 9.4 2.1 8.7 0.1 2.8 3 0 0 3 3 3 0 TSC-22/dip/bun family DENN PF02141.21 CDJ92254.1 - 2.3e-43 148.3 0.4 4.6e-43 147.3 0.4 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 CDJ92254.1 - 4.7e-11 43.3 0.3 1e-10 42.2 0.3 1.5 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 CDJ92254.1 - 2.4e-09 37.0 0.1 5e-09 36.0 0.1 1.6 1 0 0 1 1 1 1 dDENN domain SPA PF08616.10 CDJ92254.1 - 0.009 16.0 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis MFS_1 PF07690.16 CDJ92255.1 - 2.2e-05 23.5 0.9 2.3e-05 23.5 0.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Exo_endo_phos_2 PF14529.6 CDJ92256.1 - 5.3e-05 23.0 0.0 0.00017 21.4 0.0 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ92256.1 - 0.0041 16.7 0.1 0.0099 15.4 0.1 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Palm_thioest PF02089.15 CDJ92257.1 - 3.6e-85 285.7 0.0 4.2e-85 285.4 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 CDJ92257.1 - 0.00038 20.2 0.0 0.025 14.2 0.0 2.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_C1 PF00112.23 CDJ92258.1 - 2.9e-47 161.6 13.1 3.9e-47 161.1 13.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ92258.1 - 0.00049 19.0 1.6 0.00049 19.0 1.6 1.8 2 0 0 2 2 2 1 Peptidase C1-like family DUF3724 PF12521.8 CDJ92258.1 - 0.086 12.8 0.7 0.22 11.5 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) Cadherin PF00028.17 CDJ92260.1 - 4.2e-108 354.1 11.6 1.1e-16 61.0 0.0 14.2 15 0 0 15 15 15 11 Cadherin domain Cadherin_3 PF16184.5 CDJ92260.1 - 6e-08 32.7 6.5 0.059 13.4 0.1 7.2 7 0 0 7 7 7 2 Cadherin-like CHASE4 PF05228.13 CDJ92260.1 - 0.089 13.0 0.1 0.76 10.0 0.0 2.7 4 0 0 4 4 4 0 CHASE4 domain DUF5527 PF17665.1 CDJ92260.1 - 0.13 11.7 1.9 0.3 10.6 1.9 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5527) He_PIG PF05345.12 CDJ92260.1 - 0.22 11.8 19.8 0.42 10.8 0.0 8.4 10 0 0 10 10 10 0 Putative Ig domain Pyr_redox_2 PF07992.14 CDJ92263.1 - 4.6e-15 55.6 0.2 6.5e-15 55.1 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CDJ92263.1 - 2.4e-06 27.1 0.0 3.2e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDJ92263.1 - 0.00051 20.6 0.0 0.0015 19.0 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CDJ92263.1 - 0.2 10.8 0.0 0.92 8.6 0.0 1.8 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) malic PF00390.19 CDJ92264.1 - 1.8e-75 252.7 0.0 2.6e-75 252.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 CDJ92264.1 - 1.1e-32 113.3 0.3 1.5e-32 112.9 0.3 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain JmjC PF02373.22 CDJ92265.1 - 1.3e-38 131.9 0.1 3.2e-38 130.7 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 CDJ92265.1 - 8.2e-12 44.9 0.5 1.9e-11 43.7 0.5 1.6 1 0 0 1 1 1 1 jmjN domain Tudor_2 PF18104.1 CDJ92265.1 - 9.1e-10 38.0 0.4 9.1e-08 31.7 0.7 2.6 2 0 0 2 2 2 1 Jumonji domain-containing protein 2A Tudor domain PHD_2 PF13831.6 CDJ92265.1 - 4.2e-08 32.6 4.6 4.2e-08 32.6 4.6 2.9 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H_2 PF13832.6 CDJ92265.1 - 4.5e-05 23.6 16.4 0.00019 21.6 6.8 3.9 3 1 0 3 3 3 1 PHD-zinc-finger like domain PHD PF00628.29 CDJ92265.1 - 4.7e-05 23.2 1.6 4.7e-05 23.2 1.6 4.5 5 0 0 5 5 5 1 PHD-finger zf-HC5HC2H PF13771.6 CDJ92265.1 - 0.0051 17.0 1.1 0.0051 17.0 1.1 3.8 2 1 1 3 3 3 2 PHD-like zinc-binding domain PHD_4 PF16866.5 CDJ92265.1 - 7.5 6.7 14.3 0.038 14.1 1.4 3.4 3 0 0 3 3 3 0 PHD-finger HMG_box PF00505.19 CDJ92266.1 - 1.5e-16 60.6 4.0 2.7e-16 59.7 4.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ92266.1 - 6.8e-12 45.8 5.3 1.3e-11 44.9 5.3 1.5 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 CDJ92266.1 - 0.00067 19.6 6.5 0.00067 19.6 6.5 1.7 1 1 0 1 1 1 1 HMG (high mobility group) box 5 Acyl_transf_3 PF01757.22 CDJ92267.1 - 3.7e-18 65.7 45.2 3.7e-18 65.7 45.2 1.4 2 0 0 2 2 2 1 Acyltransferase family WASH-7_mid PF14744.6 CDJ92268.1 - 1e-101 340.5 3.4 1.7e-101 339.8 3.4 1.3 1 0 0 1 1 1 1 WASH complex subunit 7 WASH-7_N PF14745.6 CDJ92268.1 - 2.1e-68 231.3 0.0 3.2e-68 230.6 0.0 1.2 1 0 0 1 1 1 1 WASH complex subunit 7, N-terminal WASH-7_C PF14746.6 CDJ92268.1 - 4e-43 147.1 2.7 9.2e-43 146.0 2.7 1.6 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal Pkinase PF00069.25 CDJ92269.1 - 5.9e-58 196.3 0.0 7.4e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ92269.1 - 5.5e-38 130.7 0.0 7.3e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ92269.1 - 1.1e-05 25.0 0.0 1.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CDJ92269.1 - 0.0014 17.7 0.2 0.0035 16.3 0.2 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CDJ92269.1 - 0.014 14.8 0.7 0.023 14.1 0.2 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDJ92269.1 - 0.015 14.9 0.2 0.026 14.1 0.2 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 CDJ92269.1 - 0.07 11.9 0.5 0.11 11.2 0.5 1.4 1 1 0 1 1 1 0 Fungal protein kinase zf-UBP PF02148.19 CDJ92269.1 - 0.63 10.4 4.0 1.1 9.6 0.0 3.0 2 1 1 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein RIBIOP_C PF04950.12 CDJ92271.1 - 2.5e-120 401.3 0.0 3.8e-120 400.7 0.0 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CDJ92271.1 - 1.3e-14 54.1 0.0 3.1e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Mpp10 PF04006.12 CDJ92271.1 - 0.027 12.9 16.1 0.041 12.3 16.1 1.1 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 CDJ92271.1 - 1.5 7.0 12.9 2.4 6.4 12.9 1.2 1 0 0 1 1 1 0 CDC45-like protein SNase PF00565.17 CDJ92272.1 - 1.7e-62 208.6 7.6 6.8e-19 68.3 0.0 6.8 6 1 1 7 7 7 6 Staphylococcal nuclease homologue TUDOR PF00567.24 CDJ92272.1 - 4.4e-27 94.5 0.0 9.6e-27 93.4 0.0 1.6 1 0 0 1 1 1 1 Tudor domain DUF3297 PF11730.8 CDJ92272.1 - 0.043 13.7 0.1 0.29 11.0 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3297) Agenet PF05641.12 CDJ92272.1 - 0.049 14.1 0.0 0.21 12.1 0.0 2.2 1 0 0 1 1 1 0 Agenet domain SMN PF06003.12 CDJ92272.1 - 0.069 12.4 0.0 0.069 12.4 0.0 2.1 2 1 0 2 2 2 0 Survival motor neuron protein (SMN) 7tm_1 PF00001.21 CDJ92273.1 - 4.2e-05 23.0 1.4 4.8e-05 22.8 1.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Peptidase_M1 PF01433.20 CDJ92275.1 - 6.8e-76 254.6 0.5 9.2e-76 254.2 0.5 1.1 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CDJ92277.1 - 1.7e-30 106.6 0.1 1.7e-30 106.6 0.1 1.4 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Astacin PF01400.24 CDJ92279.1 - 1.5e-49 168.2 0.1 2.1e-49 167.7 0.1 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 CDJ92279.1 - 0.00048 19.8 0.3 0.0017 18.1 0.3 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CDJ92279.1 - 0.0029 17.5 0.0 0.0046 16.8 0.0 1.4 1 0 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.6 CDJ92279.1 - 0.01 16.3 0.1 0.021 15.3 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CDJ92279.1 - 0.024 14.8 0.1 0.038 14.1 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 CDJ92279.1 - 0.036 13.0 0.1 0.058 12.3 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Metallopep PF12044.8 CDJ92279.1 - 0.048 12.3 0.0 0.074 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Ntox44 PF15607.6 CDJ92279.1 - 0.072 13.4 0.5 0.2 12.0 0.2 1.9 2 0 0 2 2 2 0 Bacterial toxin 44 CUB PF00431.20 CDJ92279.1 - 0.086 13.2 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 CUB domain DUF4953 PF16313.5 CDJ92279.1 - 0.26 10.5 0.8 0.43 9.7 0.8 1.3 1 0 0 1 1 1 0 Met-zincin CUB PF00431.20 CDJ92280.1 - 0.016 15.5 0.0 0.017 15.5 0.0 1.2 1 0 0 1 1 1 0 CUB domain adh_short PF00106.25 CDJ92281.1 - 8.6e-26 90.6 0.1 1.2e-21 77.1 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ92281.1 - 2.3e-14 53.5 0.0 6e-13 48.9 0.0 2.1 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ92281.1 - 1.3e-09 38.2 0.1 3.1e-09 37.0 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CDJ92281.1 - 0.00077 19.0 0.2 0.0029 17.1 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Phage_Coat_Gp8 PF05371.12 CDJ92281.1 - 0.021 14.6 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 Phage major coat protein, Gp8 SAM_MT PF04445.13 CDJ92281.1 - 0.04 13.4 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase 2-Hacid_dh_C PF02826.19 CDJ92281.1 - 0.05 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CDJ92281.1 - 0.1 12.7 0.1 0.23 11.5 0.2 1.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase UPF0139 PF03669.13 CDJ92282.1 - 2.4e-47 158.7 1.7 2.8e-47 158.5 1.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) zf-C4H2 PF10146.9 CDJ92283.1 - 0.27 11.5 2.6 0.21 11.8 1.2 1.5 2 0 0 2 2 2 0 Zinc finger-containing protein Glyco_hydro_38N PF01074.22 CDJ92285.1 - 7.1e-60 202.8 0.3 1e-59 202.3 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 CDJ92285.1 - 1.2e-23 83.0 0.1 2.6e-23 82.0 0.1 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain PS-DH PF14765.6 CDJ92286.1 - 0.0026 17.0 0.0 0.0028 16.9 0.0 1.0 1 0 0 1 1 1 1 Polyketide synthase dehydratase Spore_III_AE PF09546.10 CDJ92287.1 - 0.019 14.2 3.9 0.033 13.4 3.9 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AE (spore_III_AE) Neur_chan_LBD PF02931.23 CDJ92288.1 - 2.5e-40 138.2 0.2 3.4e-40 137.8 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ92288.1 - 7.5e-11 42.5 5.3 1.3e-09 38.4 1.6 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Vps55 PF04133.14 CDJ92288.1 - 0.042 13.8 1.6 0.12 12.4 1.6 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting 55 Tetraspanin PF00335.20 CDJ92288.1 - 0.067 12.9 1.7 0.24 11.1 1.9 1.9 1 1 0 1 1 1 0 Tetraspanin family PrgI PF12666.7 CDJ92288.1 - 0.33 11.7 3.4 0.42 11.3 0.7 2.5 1 1 1 2 2 2 0 PrgI family protein HisKA_7TM PF16927.5 CDJ92288.1 - 1.4 8.9 8.8 0.36 10.8 3.8 2.4 2 1 1 3 3 3 0 N-terminal 7TM region of histidine kinase Neurochondrin PF05536.11 CDJ92289.1 - 2.2e-10 39.6 0.8 4.1e-10 38.7 0.3 1.5 1 1 0 2 2 2 1 Neurochondrin Hormone_recep PF00104.30 CDJ92290.1 - 6.4e-13 48.8 0.1 8.6e-13 48.3 0.1 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor SF3A3 PF16837.5 CDJ92290.1 - 0.056 14.0 0.1 0.11 13.0 0.1 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Sec15 PF04091.12 CDJ92290.1 - 0.093 12.1 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like Ion_trans_2 PF07885.16 CDJ92291.1 - 2.8e-33 113.7 20.5 2.7e-18 65.7 2.9 2.9 3 0 0 3 3 3 2 Ion channel AIRS_C PF02769.22 CDJ92292.1 - 3.7e-20 72.6 0.7 5.6e-20 72.0 0.7 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain Tegument_dsDNA PF12818.7 CDJ92292.1 - 0.026 13.7 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 dsDNA viral tegument protein Peptidase_S8 PF00082.22 CDJ92294.1 - 1e-70 238.4 0.0 1.6e-70 237.8 0.0 1.2 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.8 CDJ92294.1 - 9.7e-46 155.6 0.0 1.7e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 Tripeptidyl peptidase II TPPII_N PF12583.8 CDJ92294.1 - 0.0074 16.9 0.8 0.022 15.3 0.0 2.0 2 0 0 2 2 2 1 Tripeptidyl peptidase II N terminal RVT_1 PF00078.27 CDJ92295.1 - 4.2e-08 33.0 0.0 7.4e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C4 PF00105.18 CDJ92296.1 - 1.1e-26 93.1 14.5 1.1e-26 93.1 14.5 1.8 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ92296.1 - 1.2e-25 90.4 1.5 2.6e-25 89.2 1.5 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Tfb2_C PF18307.1 CDJ92296.1 - 0.17 12.3 0.5 0.63 10.5 0.5 2.0 1 0 0 1 1 1 0 Transcription factor Tfb2 (p52) C-terminal domain Arginase PF00491.21 CDJ92298.1 - 1.7e-51 175.4 0.0 2e-51 175.2 0.0 1.0 1 0 0 1 1 1 1 Arginase family DUF1647 PF07801.11 CDJ92299.1 - 1.5e-28 99.3 0.1 2.6e-28 98.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) Peptidase_M13_N PF05649.13 CDJ92300.1 - 4.5e-63 214.2 1.5 7e-63 213.6 1.5 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 CDJ92300.1 - 1.2e-60 204.6 0.2 1.9e-60 204.0 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M13 SCVP PF17619.2 CDJ92301.1 - 1.1e-12 48.6 0.0 1.2e-12 48.5 0.0 1.0 1 0 0 1 1 1 1 Secreted clade V proteins LON_substr_bdg PF02190.16 CDJ92302.1 - 3.2e-14 53.3 0.4 4.1e-14 52.9 0.4 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain DB PF01682.19 CDJ92303.1 - 6.4e-16 58.5 17.1 9e-16 58.0 17.1 1.2 1 0 0 1 1 1 1 DB module LepB_GAP_N PF18172.1 CDJ92305.1 - 0.13 12.1 0.0 0.34 10.8 0.0 1.6 2 0 0 2 2 2 0 LepB GAP domain N-terminal subdomain LMBR1 PF04791.16 CDJ92305.1 - 0.16 10.8 0.1 0.19 10.6 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CENP-H PF05837.12 CDJ92305.1 - 0.36 11.3 1.8 0.66 10.4 0.1 2.2 2 1 0 2 2 2 0 Centromere protein H (CENP-H) Globin PF00042.22 CDJ92306.1 - 1.6e-17 64.1 0.0 2.3e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Globin Adaptin_N PF01602.20 CDJ92306.1 - 0.14 10.6 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Adaptin N terminal region ZYG-11_interact PF05884.12 CDJ92307.1 - 3.9e-30 105.3 5.1 4.3e-30 105.2 5.1 1.0 1 0 0 1 1 1 1 Interactor of ZYG-11 DUF148 PF02520.17 CDJ92308.1 - 1.9e-13 50.5 4.1 2.8e-13 49.9 4.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF148 Lipase_chap PF03280.14 CDJ92308.1 - 0.00062 19.8 9.9 0.17 11.8 5.0 2.2 1 1 1 2 2 2 2 Proteobacterial lipase chaperone protein HMG_box PF00505.19 CDJ92308.1 - 0.017 15.5 1.8 4 7.9 0.0 2.7 1 1 0 2 2 2 0 HMG (high mobility group) box OSCP PF00213.18 CDJ92308.1 - 0.052 13.7 1.0 4.9 7.3 0.0 2.1 1 1 1 2 2 2 0 ATP synthase delta (OSCP) subunit Lebercilin PF15619.6 CDJ92308.1 - 0.059 13.0 3.3 0.087 12.5 3.3 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF3106 PF11304.8 CDJ92308.1 - 0.1 13.1 4.4 0.2 12.2 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) Uso1_p115_head PF04869.14 CDJ92309.1 - 6.7e-38 130.6 0.7 1.3e-37 129.6 0.7 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Arm_vescicular PF18770.1 CDJ92309.1 - 3.5e-16 58.9 0.1 1.4e-15 56.9 0.1 2.2 1 0 0 1 1 1 1 Armadillo tether-repeat of vescicular transport factor Tti2 PF10521.9 CDJ92309.1 - 0.00031 20.4 0.3 0.0039 16.8 0.0 2.8 3 0 0 3 3 3 1 Tti2 family Cnd1 PF12717.7 CDJ92309.1 - 0.0015 18.6 0.9 0.011 15.8 0.2 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDJ92309.1 - 0.011 16.1 2.0 0.16 12.4 0.2 3.1 1 1 1 2 2 2 0 HEAT repeats Atx10homo_assoc PF09759.9 CDJ92309.1 - 0.02 14.9 5.7 0.031 14.3 2.4 2.9 3 1 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 CDJ92309.1 - 1.2 9.2 3.3 38 4.5 0.0 4.3 4 1 1 5 5 5 0 Armadillo/beta-catenin-like repeat Rhodanese PF00581.20 CDJ92310.1 - 6.6e-23 81.3 0.0 1.7e-14 54.3 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain SymE_toxin PF08845.10 CDJ92310.1 - 0.05 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Toxin SymE, type I toxin-antitoxin system AIRS_C PF02769.22 CDJ92311.1 - 2.6e-19 69.9 0.7 4.3e-19 69.2 0.7 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain FGAR-AT_linker PF18072.1 CDJ92311.1 - 1.2e-10 41.8 0.0 2.4e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain FGAR-AT_N PF18076.1 CDJ92311.1 - 4.8e-07 29.8 0.0 1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal ABC_tran PF00005.27 CDJ92312.2 - 6.2e-28 98.0 0.1 9.2e-28 97.5 0.1 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 CDJ92312.2 - 3.4e-15 56.0 16.8 5.1e-15 55.4 16.8 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 CDJ92312.2 - 6.6e-09 36.0 0.1 0.00023 21.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDJ92312.2 - 0.00019 20.9 0.2 0.16 11.4 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CDJ92312.2 - 0.0028 18.2 2.7 0.023 15.2 2.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CDJ92312.2 - 0.023 14.5 0.1 0.064 13.0 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4162 PF13732.6 CDJ92312.2 - 0.12 13.1 0.0 0.27 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) RsgA_GTPase PF03193.16 CDJ92312.2 - 0.13 12.2 0.1 0.32 10.9 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase Collagen PF01391.18 CDJ92313.1 - 3.7e-25 87.4 116.1 3.6e-10 39.5 37.8 3.9 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ92313.1 - 5e-20 71.3 0.3 6.4e-20 71.0 0.3 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain DUF3741 PF12552.8 CDJ92314.1 - 0.05 13.5 0.0 0.62 10.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3741) Aa_trans PF01490.18 CDJ92315.1 - 3.8e-27 95.1 38.5 3.8e-26 91.8 38.5 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CDJ92315.1 - 9.3e-07 28.2 4.6 9.3e-07 28.2 4.6 2.9 2 1 1 3 3 3 1 Tryptophan/tyrosine permease family DUF4267 PF14087.6 CDJ92315.1 - 2.1 8.4 5.5 1.9 8.6 0.1 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4267) Phage_holin_3_6 PF07332.11 CDJ92316.1 - 0.0066 16.5 0.2 0.0066 16.5 0.2 4.0 4 0 0 4 4 4 2 Putative Actinobacterial Holin-X, holin superfamily III Coilin_N PF15862.5 CDJ92316.1 - 0.016 15.0 0.0 0.026 14.3 0.0 1.5 1 1 0 1 1 1 0 Coilin N-terminus DUF4298 PF14131.6 CDJ92316.1 - 0.11 12.5 0.0 7.8 6.5 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) DUF3566 PF12089.8 CDJ92316.1 - 0.9 9.9 4.7 0.62 10.4 0.2 3.0 3 0 0 3 3 3 0 Transmembrane domain of unknown function (DUF3566) DUF996 PF06195.13 CDJ92316.1 - 3.9 7.8 12.0 0.23 11.7 1.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF996) DUF1218 PF06749.12 CDJ92316.1 - 6.3 7.4 9.3 0.38 11.3 1.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) DUF1287 PF06940.11 CDJ92318.1 - 0.033 13.8 0.0 0.043 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) Gp-FAR-1 PF05823.12 CDJ92318.1 - 0.065 13.6 1.3 0.23 11.8 0.3 1.8 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Proteasom_PSMB PF10508.9 CDJ92319.1 - 2.2e-40 138.6 0.0 2.6e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit FAD_binding_1 PF00667.20 CDJ92319.1 - 0.19 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain zf-U11-48K PF05253.12 CDJ92320.1 - 0.08 12.9 0.5 9 6.3 0.1 2.5 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger Aldedh PF00171.22 CDJ92321.1 - 2.4e-163 543.9 0.0 3.8e-162 540.0 0.0 1.9 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 CDJ92322.1 - 2.1e-05 23.2 0.3 2.7e-05 22.9 0.3 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 CDJ92323.1 - 8.6e-22 77.3 0.0 1e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family zf-C2H2_4 PF13894.6 CDJ92324.1 - 0.0064 17.2 1.1 0.0064 17.2 1.1 17.0 18 1 0 18 18 18 6 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CDJ92324.1 - 0.0089 15.8 0.6 0.0089 15.8 0.6 7.7 10 0 0 10 10 9 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 CDJ92324.1 - 0.0099 16.3 1.5 0.0099 16.3 1.5 13.4 14 1 0 14 14 12 4 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 CDJ92324.1 - 0.032 14.9 26.6 0.26 12.0 0.2 7.1 7 0 0 7 7 7 0 Zinc finger C2H2-type, 3 repeats DUF1677 PF07911.13 CDJ92324.1 - 0.15 12.5 2.4 2.1 8.8 0.2 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1677) zf-C2H2_jaz PF12171.8 CDJ92324.1 - 0.49 10.7 0.0 0.49 10.7 0.0 6.0 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding OrsD PF12013.8 CDJ92324.1 - 0.54 10.7 0.0 0.54 10.7 0.0 7.7 10 0 0 10 10 9 0 Orsellinic acid/F9775 biosynthesis cluster protein D PhnA_Zn_Ribbon PF08274.12 CDJ92324.1 - 1.5 8.9 5.9 1 9.4 0.0 3.9 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-C2H2_aberr PF17017.5 CDJ92324.1 - 2.1 8.4 23.8 7.3 6.7 1.5 5.3 5 0 0 5 5 5 0 Aberrant zinc-finger zf_C2H2_ZHX PF18387.1 CDJ92324.1 - 2.7 7.7 21.7 5.3 6.8 0.2 6.2 6 0 0 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain AKAP95 PF04988.12 CDJ92324.1 - 6.4 7.0 10.9 2.1 8.5 0.5 3.8 4 0 0 4 4 4 0 A-kinase anchoring protein 95 (AKAP95) GILT PF03227.16 CDJ92325.1 - 3.4e-25 88.3 1.3 4.2e-25 88.0 0.7 1.4 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Thioredoxin_4 PF13462.6 CDJ92325.1 - 0.0088 16.2 0.0 4.5 7.4 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin Glutaredoxin PF00462.24 CDJ92325.1 - 0.027 14.7 0.2 0.21 11.8 0.1 2.2 2 0 0 2 2 2 0 Glutaredoxin Thioredoxin_2 PF13098.6 CDJ92325.1 - 0.11 12.9 0.6 0.24 11.9 0.1 1.7 1 1 1 2 2 2 0 Thioredoxin-like domain MFS_1 PF07690.16 CDJ92326.1 - 6.4e-10 38.5 3.4 7.3e-10 38.3 3.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TMEM144 PF07857.12 CDJ92327.1 - 7.3e-109 363.8 11.6 9.2e-109 363.5 11.6 1.1 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 CDJ92327.1 - 1.5e-07 31.1 13.0 9.7e-06 25.1 1.2 2.2 2 0 0 2 2 2 2 Sugar transport protein Multi_Drug_Res PF00893.19 CDJ92327.1 - 0.0026 18.4 5.3 0.0083 16.8 0.1 3.0 2 1 0 2 2 2 1 Small Multidrug Resistance protein Ureide_permease PF07168.11 CDJ92327.1 - 0.031 13.0 10.1 0.093 11.5 0.4 2.6 2 1 0 2 2 2 0 Ureide permease HOK_GEF PF01848.16 CDJ92327.1 - 1.6 8.2 6.0 15 5.1 0.3 2.7 2 0 0 2 2 2 0 Hok/gef family TMEM144 PF07857.12 CDJ92328.1 - 2.9e-107 358.5 16.4 3.7e-107 358.2 16.4 1.1 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 CDJ92328.1 - 1.1e-09 38.0 15.1 5.2e-07 29.3 2.9 2.2 2 0 0 2 2 2 2 Sugar transport protein Multi_Drug_Res PF00893.19 CDJ92328.1 - 0.0063 17.2 0.9 0.0063 17.2 0.9 2.8 2 2 0 2 2 2 1 Small Multidrug Resistance protein DUF1129 PF06570.11 CDJ92328.1 - 0.01 15.3 1.6 0.029 13.9 0.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) UPF0182 PF03699.13 CDJ92328.1 - 0.2 9.8 2.1 0.2 9.8 2.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Thioredoxin_8 PF13905.6 CDJ92329.1 - 8.2e-28 96.6 0.0 1.2e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CDJ92329.1 - 1.3e-09 38.0 0.0 1.7e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 CDJ92329.1 - 2.7e-08 33.7 0.0 2.7e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_9 PF14595.6 CDJ92329.1 - 6e-06 26.1 0.0 2.4e-05 24.1 0.0 1.8 1 1 1 2 2 2 1 Thioredoxin Redoxin PF08534.10 CDJ92329.1 - 1.4e-05 24.8 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 CDJ92329.1 - 0.00033 20.6 0.0 0.00046 20.1 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_2 PF13098.6 CDJ92329.1 - 0.00069 20.0 0.0 0.001 19.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Glutaredoxin PF00462.24 CDJ92329.1 - 0.032 14.4 1.0 4.5 7.6 0.4 2.7 2 1 0 2 2 2 0 Glutaredoxin Ish1 PF10281.9 CDJ92329.1 - 0.091 13.1 0.3 4.3 7.7 0.3 2.4 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein AAA_12 PF13087.6 CDJ92330.1 - 5.6e-05 22.9 0.0 7e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain DUF1759 PF03564.15 CDJ92331.1 - 1.5e-21 76.9 0.3 2.5e-21 76.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) rve PF00665.26 CDJ92331.1 - 7.5e-16 58.4 0.3 2.3e-14 53.6 0.0 2.6 3 0 0 3 3 3 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ92331.1 - 1.7e-11 44.1 0.3 4.3e-11 42.7 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CDJ92331.1 - 4.3e-07 30.0 0.2 1e-06 28.9 0.2 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 CDJ92331.1 - 0.00028 20.6 0.0 0.001 18.8 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain TTR-52 PF01060.23 CDJ92332.1 - 0.00023 21.8 0.0 0.00038 21.1 0.0 1.3 1 0 0 1 1 1 1 Transthyretin-like family Leu_leader PF08054.11 CDJ92332.1 - 0.069 12.7 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Leucine operon leader peptide AMP-binding PF00501.28 CDJ92333.1 - 8.4e-109 364.0 0.0 1.1e-108 363.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ92333.1 - 9.3e-06 26.5 0.2 5.6e-05 24.1 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain HAD_2 PF13419.6 CDJ92334.1 - 1.1e-19 71.2 0.0 1.9e-19 70.4 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDJ92334.1 - 2.5e-18 67.2 0.0 1.2e-17 64.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CDJ92334.1 - 2.7e-10 40.2 0.0 5.7e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 CDJ92334.1 - 1.5e-06 28.8 0.0 2.3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDJ92334.1 - 0.004 16.9 0.0 0.12 12.1 0.0 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CDJ92334.1 - 0.033 14.3 0.0 5 7.3 0.0 2.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF4245 PF14030.6 CDJ92336.1 - 0.16 11.9 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) ABC2_membrane_3 PF12698.7 CDJ92337.1 - 7.7e-09 35.1 11.0 8.4e-09 35.0 11.0 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein Adap_comp_sub PF00928.21 CDJ92339.1 - 1.5e-18 67.1 0.0 1.7e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Ribosomal_L1 PF00687.21 CDJ92340.1 - 3e-45 154.5 3.1 3.5e-45 154.2 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Calici_MSP PF05752.11 CDJ92341.1 - 0.014 15.2 1.2 0.062 13.1 0.3 2.2 2 0 0 2 2 2 0 Calicivirus minor structural protein FAM199X PF15814.5 CDJ92341.1 - 0.032 13.3 3.0 0.038 13.1 0.3 2.0 2 0 0 2 2 2 0 Protein family FAM199X DUF1387 PF07139.11 CDJ92341.1 - 8.3 6.0 9.4 11 5.6 0.0 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF1387) Myb_DNA-bind_2 PF08914.11 CDJ92342.1 - 0.022 14.9 0.1 0.029 14.5 0.1 1.2 1 0 0 1 1 1 0 Rap1 Myb domain DUF1759 PF03564.15 CDJ92343.1 - 8.2e-15 55.0 0.0 1.2e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) DUF3387 PF11867.8 CDJ92343.1 - 0.049 13.0 0.1 0.079 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) Sigma70_r3 PF04539.16 CDJ92343.1 - 0.091 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 region 3 F-box PF00646.33 CDJ92344.1 - 0.022 14.7 0.1 0.13 12.2 0.1 2.3 2 0 0 2 2 2 0 F-box domain Patched PF02460.18 CDJ92345.1 - 2.9e-179 597.9 0.0 3.3e-179 597.7 0.0 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 CDJ92345.1 - 8.7e-41 139.3 9.2 8.7e-41 139.3 9.2 1.8 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 CDJ92345.1 - 3.4e-05 22.9 12.7 6.3e-05 22.1 12.7 1.5 1 1 0 1 1 1 1 MMPL family TAN PF11640.8 CDJ92346.1 - 0.068 13.3 0.2 0.22 11.7 0.2 1.8 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair REF PF05755.12 CDJ92346.1 - 0.069 12.9 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) 7TMR-HDED PF07697.11 CDJ92346.1 - 0.089 12.9 1.4 2.2 8.4 0.7 2.2 2 0 0 2 2 2 0 7TM-HD extracellular Exo_endo_phos PF03372.23 CDJ92346.1 - 0.13 11.7 0.0 2.1 7.8 0.0 2.7 2 1 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family DUF3877 PF12993.7 CDJ92347.1 - 0.044 13.7 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) RhoGEF PF00621.20 CDJ92348.1 - 1.4e-22 80.8 1.8 2.5e-22 80.0 1.8 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_16 PF17838.1 CDJ92348.1 - 1.5e-07 31.3 0.1 6.1e-07 29.3 0.0 2.0 2 1 0 2 2 2 1 PH domain PH_5 PF15405.6 CDJ92348.1 - 0.0077 16.3 0.2 0.033 14.3 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_10 PF15411.6 CDJ92348.1 - 0.082 13.2 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain RBD PF02196.15 CDJ92349.1 - 0.0021 18.1 0.0 0.0028 17.7 0.0 1.2 1 0 0 1 1 1 1 Raf-like Ras-binding domain Stn1 PF10451.9 CDJ92351.1 - 0.14 11.0 0.1 0.32 9.9 0.1 1.5 1 0 0 1 1 1 0 Telomere regulation protein Stn1 EF-hand_1 PF00036.32 CDJ92352.1 - 3.1e-40 132.7 15.8 3.6e-10 38.6 0.1 4.5 4 1 1 5 5 5 4 EF hand EF-hand_7 PF13499.6 CDJ92352.1 - 7.4e-35 119.2 4.6 7.8e-18 64.7 2.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ92352.1 - 2.1e-31 107.5 13.4 3.8e-13 49.1 0.1 4.2 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CDJ92352.1 - 2.1e-30 102.0 7.3 5e-09 35.4 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CDJ92352.1 - 2.6e-23 80.4 8.3 4.8e-06 25.8 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CDJ92352.1 - 2.3e-12 47.0 0.2 7.3e-06 26.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CDJ92352.1 - 8.3e-10 38.6 2.3 0.001 19.0 0.6 2.8 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.10 CDJ92352.1 - 0.00011 22.2 1.8 0.00016 21.7 0.4 2.0 2 1 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.13 CDJ92352.1 - 0.00017 21.6 0.0 1.2 9.2 0.0 3.3 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.9 CDJ92352.1 - 0.00061 20.1 0.0 0.87 9.9 0.1 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CDJ92352.1 - 0.0012 19.7 0.1 0.013 16.4 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 CDJ92352.1 - 0.0079 16.4 0.9 3 8.1 0.2 3.0 1 1 3 4 4 4 1 Dockerin type I domain Caleosin PF05042.13 CDJ92352.1 - 0.015 15.3 0.5 14 5.6 0.0 3.4 1 1 3 4 4 4 0 Caleosin related protein PMBR PF09373.10 CDJ92352.1 - 0.032 14.4 0.1 31 4.9 0.0 4.1 5 0 0 5 5 5 0 Pseudomurein-binding repeat DUF4891 PF16232.5 CDJ92352.1 - 0.04 14.4 0.0 6.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4891) TerB PF05099.13 CDJ92352.1 - 0.096 12.6 0.3 2.6 8.0 0.1 2.2 1 1 1 2 2 2 0 Tellurite resistance protein TerB EF-hand_10 PF14788.6 CDJ92352.1 - 1.6 8.7 5.9 0.54 10.2 0.3 3.0 4 0 0 4 4 4 0 EF hand VCBS PF13517.6 CDJ92352.1 - 9.8 6.9 6.9 13 6.5 2.1 2.6 2 2 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Got1 PF04178.12 CDJ92353.1 - 1e-18 67.8 6.6 1e-18 67.8 6.6 1.5 1 1 0 1 1 1 1 Got1/Sft2-like family MFS_1 PF07690.16 CDJ92353.1 - 0.00031 19.8 1.5 0.00037 19.5 1.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily NDUF_B12 PF08122.12 CDJ92354.1 - 7.2e-08 32.4 0.7 1e-07 31.9 0.7 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Peptidase_M14 PF00246.24 CDJ92355.1 - 2.6e-81 273.6 0.0 1.1e-80 271.6 0.0 1.8 2 0 0 2 2 2 1 Zinc carboxypeptidase Propep_M14 PF02244.16 CDJ92355.1 - 6.6e-06 26.4 0.0 2.6e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Carboxypeptidase activation peptide DUF543 PF04418.12 CDJ92356.1 - 5e-19 68.1 0.3 6.2e-19 67.8 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) DUF2373 PF10180.9 CDJ92357.1 - 0.016 15.0 0.0 0.09 12.6 0.0 2.2 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2373) Cpn60_TCP1 PF00118.24 CDJ92358.1 - 1.7e-155 518.4 10.2 1.9e-155 518.2 10.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1894 PF08979.11 CDJ92358.1 - 0.02 15.3 0.3 10 6.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1894) CLASP_N PF12348.8 CDJ92359.1 - 1e-17 64.5 5.1 9e-10 38.5 0.8 2.2 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 CDJ92359.1 - 3.3e-13 48.7 5.4 5.2e-05 23.2 0.1 5.6 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 CDJ92359.1 - 1.3e-11 44.7 3.3 0.0073 16.7 0.0 5.3 2 2 3 5 5 5 4 HEAT repeats HEAT_EZ PF13513.6 CDJ92359.1 - 3.6e-09 36.9 0.3 0.0034 17.9 0.0 5.2 5 0 0 5 5 5 1 HEAT-like repeat Cnd1 PF12717.7 CDJ92359.1 - 7.2e-06 26.1 8.2 0.0088 16.1 0.0 3.6 3 2 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CDJ92359.1 - 2.4e-05 24.9 0.6 2.4 8.8 0.0 4.1 4 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region TAN PF11640.8 CDJ92359.1 - 0.0016 18.6 4.0 0.06 13.5 0.9 3.4 2 2 1 3 3 3 1 Telomere-length maintenance and DNA damage repair Cnd3 PF12719.7 CDJ92359.1 - 0.0025 17.1 0.9 0.15 11.2 0.1 2.4 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Cohesin_HEAT PF12765.7 CDJ92359.1 - 0.0039 17.5 6.0 0.07 13.4 0.3 3.3 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion DUF3385 PF11865.8 CDJ92359.1 - 0.045 13.7 0.7 4.8 7.1 0.1 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) Arm PF00514.23 CDJ92359.1 - 0.1 12.7 0.4 1.4 9.1 0.0 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat BAR PF03114.18 CDJ92360.1 - 0.00011 22.0 4.8 0.00014 21.6 4.8 1.1 1 0 0 1 1 1 1 BAR domain DUF4763 PF15960.5 CDJ92360.1 - 0.0019 17.6 1.0 0.0026 17.1 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) BAR_3 PF16746.5 CDJ92360.1 - 0.0081 15.9 10.8 0.022 14.4 3.0 2.0 1 1 1 2 2 2 2 BAR domain of APPL family UPF0231 PF06062.11 CDJ92360.1 - 0.12 12.6 0.8 2.4 8.4 0.5 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0231) TSNAXIP1_N PF15739.5 CDJ92360.1 - 0.13 12.6 3.7 0.12 12.8 1.7 1.8 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus PI3K_P85_iSH2 PF16454.5 CDJ92360.1 - 8 6.0 15.0 34 4.0 0.2 2.9 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF236 PF03057.14 CDJ92361.1 - 3.8e-18 65.1 2.3 2e-08 34.0 0.8 2.5 2 0 0 2 2 2 2 DUF236 repeat Eapp_C PF10238.9 CDJ92362.1 - 1.5e-42 145.2 3.8 1.5e-42 145.2 3.8 2.7 3 0 0 3 3 3 1 E2F-associated phosphoprotein Fer4_22 PF17179.4 CDJ92362.1 - 0.21 12.5 2.5 0.82 10.5 2.5 2.0 1 0 0 1 1 1 0 4Fe-4S dicluster domain Eaf7 PF07904.13 CDJ92362.1 - 4.1 7.8 6.4 23 5.4 6.2 2.3 1 1 0 1 1 1 0 Chromatin modification-related protein EAF7 PRKCSH PF07915.13 CDJ92363.1 - 1.3e-09 38.9 3.5 3.2e-09 37.7 3.5 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein RNA_pol_L_2 PF13656.6 CDJ92364.1 - 2.3e-29 101.0 0.1 2.9e-29 100.6 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CDJ92364.1 - 1.2e-11 43.8 0.0 1.8e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SHNi-TPR PF10516.9 CDJ92364.1 - 0.057 12.9 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 SHNi-TPR GATase_6 PF13522.6 CDJ92365.1 - 2.2e-14 53.8 0.0 4.2e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CDJ92365.1 - 6.5e-11 42.2 0.0 1.3e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 CDJ92365.1 - 8.7e-06 25.3 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MMADHC PF10229.9 CDJ92366.1 - 6.1e-82 275.4 0.1 7.2e-82 275.2 0.1 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein AAA_11 PF13086.6 CDJ92366.1 - 0.046 13.5 0.1 0.067 13.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain NAAA-beta PF15508.6 CDJ92367.1 - 3.2e-10 40.1 0.2 6.5e-10 39.2 0.2 1.5 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase CBAH PF02275.18 CDJ92367.1 - 3.2e-09 36.9 0.0 4.2e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family CD36 PF01130.21 CDJ92368.1 - 2.1e-112 376.0 0.0 2.7e-112 375.7 0.0 1.0 1 0 0 1 1 1 1 CD36 family RVT_1 PF00078.27 CDJ92368.1 - 5.2e-10 39.2 0.0 8.7e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CAF1C_H4-bd PF12265.8 CDJ92370.1 - 0.17 12.2 0.0 0.21 11.9 0.0 1.2 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex Glyco_hydro_56 PF01630.18 CDJ92372.1 - 7.9e-97 324.3 0.1 1e-96 323.9 0.1 1.1 1 0 0 1 1 1 1 Hyaluronidase EGF_2 PF07974.13 CDJ92372.1 - 0.011 16.1 3.2 0.037 14.4 3.2 1.9 1 1 0 1 1 1 0 EGF-like domain EGF PF00008.27 CDJ92372.1 - 0.51 10.7 6.4 1.5 9.1 5.6 2.1 1 1 0 1 1 1 0 EGF-like domain DUF3844 PF12955.7 CDJ92372.1 - 0.91 9.7 4.7 1.8 8.7 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) EGF_alliinase PF04863.13 CDJ92372.1 - 1.4 9.4 3.5 4.9 7.6 3.5 1.9 1 0 0 1 1 1 0 Alliinase EGF-like domain RVT_1 PF00078.27 CDJ92373.1 - 1.7e-05 24.4 0.0 2.4e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNF220 PF15926.5 CDJ92374.1 - 6.6e-06 25.9 0.0 1e-05 25.3 0.0 1.2 1 1 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 PRP21_like_P PF12230.8 CDJ92374.1 - 0.00096 19.1 0.0 0.00096 19.1 0.0 1.1 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein zf_UBZ PF18439.1 CDJ92374.1 - 0.066 12.8 0.4 0.066 12.8 0.4 1.9 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 CDJ92374.1 - 0.098 13.0 1.1 0.52 10.6 0.3 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_11 PF17123.5 CDJ92374.1 - 0.12 12.1 0.7 0.12 12.1 0.7 2.2 2 0 0 2 2 2 0 RING-like zinc finger C1_2 PF03107.16 CDJ92374.1 - 0.17 12.2 2.0 2.6 8.4 0.3 2.3 2 0 0 2 2 2 0 C1 domain zf-RING_2 PF13639.6 CDJ92374.1 - 0.26 11.6 4.1 5.4 7.4 0.2 2.3 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.6 CDJ92374.1 - 1.9 8.4 5.4 6.6 6.7 0.3 2.6 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF4709 PF15821.5 CDJ92375.1 - 0.017 15.4 0.2 0.033 14.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) PC-Esterase PF13839.6 CDJ92375.1 - 0.032 14.0 0.0 0.066 12.9 0.0 1.5 1 1 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p LRR_RI_capping PF18779.1 CDJ92375.1 - 0.04 13.6 0.0 0.093 12.4 0.0 1.6 1 0 0 1 1 1 0 Capping Ribonuclease inhibitor Leucine Rich Repeat Syntaxin-6_N PF09177.11 CDJ92375.1 - 0.053 14.1 2.9 0.18 12.4 2.4 2.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Pkinase PF00069.25 CDJ92377.1 - 4.5e-17 62.3 0.1 5.1e-17 62.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ92377.1 - 1.6e-09 37.5 0.0 1.8e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ92379.1 - 1.7e-55 188.3 0.0 9.5e-55 185.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ92379.1 - 1e-20 74.2 0.1 4.5e-19 68.7 0.0 2.7 3 0 0 3 3 3 1 Protein tyrosine kinase APH PF01636.23 CDJ92379.1 - 4.4e-07 30.1 0.4 0.00028 20.9 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 CDJ92379.1 - 0.058 13.0 0.3 0.17 11.5 0.3 1.7 1 1 0 1 1 1 0 RIO1 family MFS_1 PF07690.16 CDJ92380.1 - 8e-26 90.8 17.5 4e-25 88.5 18.1 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ92380.1 - 4.7e-23 81.8 11.1 6.7e-23 81.3 11.1 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter IgGFc_binding PF17517.2 CDJ92381.1 - 3.5e-32 111.8 9.7 4.6e-32 111.5 9.7 1.1 1 0 0 1 1 1 1 IgGFc binding protein Methyltrn_RNA_3 PF02598.17 CDJ92382.1 - 2.5e-83 279.9 0.0 3.4e-83 279.5 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.19 CDJ92382.1 - 0.079 13.1 0.1 5.4 7.2 0.0 2.6 3 0 0 3 3 3 0 SpoU rRNA Methylase family PS_Dcarbxylase PF02666.15 CDJ92383.1 - 8.1e-45 152.8 0.0 1.1e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Neur_chan_LBD PF02931.23 CDJ92384.1 - 3.3e-49 167.3 0.0 5.1e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ92384.1 - 1.8e-26 93.6 3.4 1.7e-24 87.2 0.1 2.2 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CDJ92385.1 - 4.2e-52 176.7 0.1 6e-52 176.2 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ92385.1 - 3.5e-39 135.3 4.2 1.1e-36 127.1 4.2 2.2 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region SecY PF00344.20 CDJ92385.1 - 0.024 13.9 0.8 0.045 13.0 0.8 1.4 1 1 0 1 1 1 0 SecY translocase Neur_chan_LBD PF02931.23 CDJ92386.1 - 6.4e-51 172.8 0.1 9.5e-51 172.3 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ92386.1 - 1e-38 133.8 6.6 5.1e-33 115.1 3.6 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region PLAT PF01477.23 CDJ92387.1 - 2.9e-05 24.6 0.0 3.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 PLAT/LH2 domain ATS3 PF06232.11 CDJ92387.1 - 0.00048 20.0 0.1 0.00065 19.6 0.1 1.2 1 0 0 1 1 1 1 Embryo-specific protein 3, (ATS3) Sec1 PF00995.23 CDJ92388.1 - 7.3e-122 408.5 0.9 8.3e-122 408.3 0.9 1.0 1 0 0 1 1 1 1 Sec1 family GTP_EFTU PF00009.27 CDJ92389.1 - 2.2e-49 167.7 0.0 3.6e-49 167.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 CDJ92389.1 - 9.4e-37 126.3 10.6 2e-36 125.2 10.6 1.6 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_C PF00679.24 CDJ92389.1 - 1.4e-22 79.6 0.0 3.1e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 CDJ92389.1 - 1.8e-20 72.9 0.0 4.5e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 CDJ92389.1 - 7.3e-10 39.1 0.0 1.5e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CDJ92389.1 - 2.6e-06 27.4 0.4 7.4e-06 26.0 0.1 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CDJ92389.1 - 8.1e-06 25.9 0.0 1.6e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CDJ92389.1 - 0.0016 18.5 0.1 0.11 12.5 0.0 2.6 2 1 1 3 3 3 1 Dynamin family Septin PF00735.18 CDJ92389.1 - 0.0021 17.4 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Septin Roc PF08477.13 CDJ92389.1 - 0.0065 16.7 0.0 0.042 14.1 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDJ92389.1 - 0.016 14.8 0.0 0.042 13.4 0.0 1.7 1 1 0 1 1 1 0 Ras family AAA_12 PF13087.6 CDJ92390.1 - 1.5e-12 47.6 0.1 6.5e-12 45.5 0.1 2.1 2 0 0 2 2 2 1 AAA domain Med29 PF11568.8 CDJ92390.1 - 2.9e-11 43.8 0.2 2.9e-11 43.8 0.2 3.4 3 2 1 4 4 4 1 Mediator complex subunit 29 TAF4 PF05236.14 CDJ92391.1 - 0.013 15.2 0.6 0.013 15.2 0.6 1.0 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Cation_ATPase_C PF00689.21 CDJ92393.1 - 6.9e-58 195.3 1.0 1.1e-40 139.3 0.2 2.2 2 0 0 2 2 2 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CDJ92393.1 - 3e-25 89.8 2.1 5e-14 53.1 0.6 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDJ92393.1 - 7.7e-12 45.5 8.3 0.00043 20.1 0.7 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.7 CDJ92393.1 - 6.7e-05 23.4 0.0 0.003 18.0 0.1 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CDJ92394.1 - 4.9e-11 43.0 0.0 3.2e-10 40.4 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDJ92394.1 - 8.6e-09 36.0 0.0 1.1e-08 35.7 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CDJ92394.1 - 0.0076 16.3 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Ribosomal_L32p PF01783.23 CDJ92395.1 - 6.4e-09 35.9 0.4 1.1e-08 35.1 0.4 1.4 1 0 0 1 1 1 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.6 CDJ92395.1 - 0.0016 17.8 1.6 0.003 16.9 1.6 1.3 1 0 0 1 1 1 1 zinc-ribbon domain Prok-RING_1 PF14446.6 CDJ92395.1 - 0.018 15.0 1.0 0.036 14.0 1.0 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 DZR PF12773.7 CDJ92395.1 - 0.039 14.0 1.1 0.099 12.7 1.3 1.5 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 CDJ92395.1 - 0.37 10.9 2.2 1.1 9.5 0.2 2.3 1 1 1 2 2 2 0 Zinc ribbon domain Rpn3_C PF08375.11 CDJ92396.1 - 2.6e-23 82.2 2.3 7.5e-23 80.7 2.3 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 CDJ92396.1 - 5.7e-21 75.0 0.6 1.2e-20 74.0 0.1 1.8 2 0 0 2 2 2 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 CDJ92396.1 - 0.021 14.8 0.1 0.062 13.3 0.1 1.8 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family Prok-TraM PF09228.10 CDJ92396.1 - 0.022 15.1 0.1 0.11 12.9 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM TPR_2 PF07719.17 CDJ92396.1 - 0.48 10.7 10.3 1.1 9.6 1.6 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ92396.1 - 5.9 7.6 7.8 9.2 7.0 1.6 3.6 3 2 0 3 3 3 0 Tetratricopeptide repeat HSP70 PF00012.20 CDJ92397.1 - 6.8e-184 612.4 0.2 1.4e-183 611.3 0.0 1.5 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 CDJ92397.1 - 2.1e-06 26.8 0.0 3.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Raco_middle PF17651.1 CDJ92397.1 - 0.017 14.8 0.1 0.092 12.4 0.0 2.2 3 0 0 3 3 3 0 RACo middle region Rac1 PF09632.10 CDJ92397.1 - 0.058 12.6 0.0 7.2 5.7 0.1 2.3 1 1 1 2 2 2 0 Rac1-binding domain Big_5 PF13205.6 CDJ92397.1 - 0.088 13.5 0.3 0.25 12.1 0.3 1.8 1 0 0 1 1 1 0 Bacterial Ig-like domain Skp1 PF01466.19 CDJ92398.1 - 0.00011 22.2 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Ufm1 PF03671.14 CDJ92399.1 - 4.1e-31 106.9 0.2 4.7e-31 106.7 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein ANP PF00212.18 CDJ92399.1 - 0.085 13.1 0.5 0.13 12.5 0.5 1.2 1 0 0 1 1 1 0 Atrial natriuretic peptide HTH_48 PF17906.1 CDJ92401.1 - 9.1e-05 22.5 0.0 0.00023 21.2 0.0 1.7 1 1 0 1 1 1 1 HTH domain in Mos1 transposase HTH_24 PF13412.6 CDJ92401.1 - 0.0086 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 CDJ92401.1 - 0.012 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 HTH DNA binding domain HTH_Tnp_IS630 PF01710.16 CDJ92401.1 - 0.032 14.3 0.0 0.033 14.2 0.0 1.1 1 0 0 1 1 1 0 Transposase Terminase_5 PF06056.12 CDJ92401.1 - 0.035 14.0 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_AsnC-type PF13404.6 CDJ92401.1 - 0.07 13.0 0.2 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_29 PF13551.6 CDJ92401.1 - 0.079 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_50 PF18024.1 CDJ92401.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain OATP PF03137.20 CDJ92402.1 - 1.6e-56 191.7 0.6 1.9e-56 191.5 0.6 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 CDJ92402.1 - 1.3e-09 37.5 12.0 4.6e-09 35.7 12.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily tRNA_SAD PF07973.14 CDJ92403.1 - 3.4e-10 39.9 0.0 1.4e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain CAP PF00188.26 CDJ92405.1 - 1.1e-15 58.5 2.6 2.3e-15 57.5 2.6 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ92405.1 - 0.012 15.9 0.9 0.18 12.1 0.9 2.2 1 1 0 1 1 1 0 Ancylostoma-associated secreted protein related Sof1 PF04158.14 CDJ92406.1 - 4.9e-26 90.8 5.8 1.1e-25 89.8 5.8 1.6 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 CDJ92406.1 - 3.1e-16 59.5 12.8 3.9e-05 24.3 0.0 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ92406.1 - 0.00023 21.4 0.1 0.023 15.0 0.0 2.9 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Inositol_P PF00459.25 CDJ92407.1 - 8e-43 146.9 1.3 2e-42 145.6 1.3 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family FrhB_FdhB_C PF04432.13 CDJ92407.1 - 0.014 15.2 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus DUF5081 PF16887.5 CDJ92407.1 - 0.059 12.4 0.0 0.098 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5081) CagE_TrbE_VirB PF03135.14 CDJ92407.1 - 0.17 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system BAR PF03114.18 CDJ92408.1 - 2.5e-15 56.8 2.7 2.9e-15 56.6 2.7 1.0 1 0 0 1 1 1 1 BAR domain UCH PF00443.29 CDJ92409.1 - 3.1e-46 158.0 0.0 6.1e-46 157.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ92409.1 - 1.7e-09 37.8 0.3 1.1e-06 28.5 0.0 3.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CDJ92409.1 - 1.4e-06 28.5 6.4 1.4e-06 28.5 6.4 2.8 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Homeodomain PF00046.29 CDJ92410.1 - 9.1e-22 76.7 3.0 2.4e-21 75.3 3.0 1.7 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 CDJ92410.1 - 0.0005 19.5 1.2 0.0011 18.4 0.5 1.9 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 CDJ92410.1 - 0.004 17.0 0.1 0.0085 16.0 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain DUF3824 PF12868.7 CDJ92410.1 - 0.21 12.3 2.5 0.5 11.0 2.5 1.6 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF1664 PF07889.12 CDJ92411.1 - 0.014 15.4 0.8 0.04 14.0 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) YojJ PF10372.9 CDJ92411.1 - 0.018 15.2 0.4 0.067 13.3 0.1 2.2 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus DUF812 PF05667.11 CDJ92411.1 - 0.075 11.9 10.9 0.025 13.5 5.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Baculo_PEP_C PF04513.12 CDJ92411.1 - 0.23 11.5 5.5 0.39 10.8 3.5 2.4 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAT PF03127.14 CDJ92411.1 - 2 8.8 5.8 9.3 6.6 1.7 3.8 3 1 0 3 3 3 0 GAT domain Hist_deacetyl PF00850.19 CDJ92412.1 - 1.2e-65 222.0 0.0 1.7e-65 221.5 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain PAC2 PF09754.9 CDJ92412.1 - 0.0045 17.0 0.0 0.0068 16.4 0.0 1.4 1 0 0 1 1 1 1 PAC2 family Glyco_hydro_39 PF01229.17 CDJ92412.1 - 0.057 12.0 0.5 0.48 8.9 0.3 2.2 2 0 0 2 2 2 0 Glycosyl hydrolases family 39 T6SS-SciN PF12790.7 CDJ92414.1 - 0.0017 18.1 0.0 0.0018 18.0 0.0 1.1 1 0 0 1 1 1 1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 ATP_synth_reg PF14960.6 CDJ92414.1 - 0.091 12.3 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 ATP synthase regulation eIF2A PF08662.11 CDJ92415.1 - 1.2e-10 41.6 0.3 7.8e-07 29.2 0.0 3.4 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 CDJ92415.1 - 4.2e-05 23.3 0.0 8.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 CDJ92415.1 - 0.015 16.2 2.6 0.61 11.1 0.1 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat An_peroxidase PF03098.15 CDJ92416.1 - 1.1e-54 185.9 0.0 1.5e-54 185.5 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase ShK PF01549.24 CDJ92416.1 - 9.7e-05 22.8 8.8 9.7e-05 22.8 8.8 2.4 2 1 0 2 2 2 1 ShK domain-like An_peroxidase PF03098.15 CDJ92417.1 - 1.8e-167 558.1 0.0 2.1e-167 557.9 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase ShK PF01549.24 CDJ92417.1 - 4.9e-06 27.0 10.0 4.9e-06 27.0 10.0 3.2 3 0 0 3 3 3 1 ShK domain-like ShK PF01549.24 CDJ92418.1 - 3.4e-18 65.9 25.5 2e-09 37.8 8.4 2.9 3 0 0 3 3 3 2 ShK domain-like CC PF04942.14 CDJ92418.1 - 8.3e-06 25.9 4.7 3.7e-05 23.8 4.7 2.2 1 0 0 1 1 1 1 CC domain zf-CHCC PF10276.9 CDJ92418.1 - 2.4 8.3 11.0 2.3 8.4 0.3 3.0 3 0 0 3 3 3 0 Zinc-finger domain Acetyltransf_10 PF13673.7 CDJ92419.1 - 2.7e-06 27.4 0.0 4.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDJ92419.1 - 1.6e-05 25.1 0.0 2.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDJ92419.1 - 2.3e-05 24.7 0.0 0.00011 22.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDJ92419.1 - 0.075 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein PanZ PF12568.8 CDJ92419.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ RT_RNaseH_2 PF17919.1 CDJ92421.1 - 2.8e-31 107.5 0.0 6.2e-31 106.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ92421.1 - 1e-28 100.4 0.1 2.7e-28 99.0 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDJ92421.1 - 1e-26 93.3 0.0 1.9e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase HOCHOB PF17943.1 CDJ92421.1 - 0.2 12.4 0.8 0.61 10.8 0.0 2.1 3 0 0 3 3 3 0 Homeobox-cysteine loop-homeobox Innexin PF00876.18 CDJ92422.1 - 2.9e-91 306.4 15.5 3.3e-91 306.2 15.5 1.0 1 0 0 1 1 1 1 Innexin SapB_2 PF03489.17 CDJ92424.1 - 1.4e-05 25.1 2.4 1.4e-05 25.1 2.4 2.0 2 0 0 2 2 2 1 Saposin-like type B, region 2 SapB_1 PF05184.15 CDJ92424.1 - 0.00084 19.3 0.7 0.00084 19.3 0.7 2.7 3 1 0 3 3 3 1 Saposin-like type B, region 1 Uteroglobin PF01099.17 CDJ92424.1 - 0.032 14.6 0.4 0.16 12.3 0.1 1.9 1 1 1 2 2 2 0 Uteroglobin family Exo_endo_phos_2 PF14529.6 CDJ92425.1 - 9.5e-06 25.5 0.0 2.3e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ92425.1 - 0.009 15.5 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CNOT1_TTP_bind PF16417.5 CDJ92426.1 - 0.0041 16.3 0.4 0.0058 15.8 0.4 1.3 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain AbiH PF14253.6 CDJ92426.1 - 0.34 10.7 1.7 0.66 9.8 1.7 1.5 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH GLYCAM-1 PF05242.11 CDJ92426.1 - 0.35 11.0 3.8 0.43 10.7 0.2 2.2 1 1 1 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) TMEM131_like PF12371.8 CDJ92428.1 - 1.2e-16 60.7 3.9 3.7e-14 52.7 0.1 4.2 4 0 0 4 4 4 2 Transmembrane protein 131-like ASH PF15780.5 CDJ92428.1 - 5.6e-11 42.5 0.8 3.3e-05 24.0 0.0 5.0 5 0 0 5 5 5 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin CBS PF00571.28 CDJ92430.1 - 0.00018 21.9 0.1 0.029 14.8 0.0 2.6 2 0 0 2 2 2 2 CBS domain Evr1_Alr PF04777.13 CDJ92431.1 - 1.1e-20 73.9 0.0 2.9e-20 72.6 0.0 1.8 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin PF00085.20 CDJ92431.1 - 9.3e-17 60.9 0.0 8.3e-16 57.9 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 CDJ92431.1 - 5.7e-06 26.6 0.1 1.9e-05 24.9 0.1 1.9 1 0 0 1 1 1 1 Thioredoxin-like QSOX_Trx1 PF18108.1 CDJ92431.1 - 4.7e-05 23.5 0.0 9.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 QSOX Trx-like domain FAD_SOX PF18371.1 CDJ92431.1 - 0.00022 21.5 0.0 0.0014 18.9 0.0 2.3 1 1 0 1 1 1 1 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Thioredoxin_2 PF13098.6 CDJ92431.1 - 0.11 12.9 0.0 0.62 10.5 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin-like domain PAN_1 PF00024.26 CDJ92432.1 - 0.00057 19.8 2.8 0.00057 19.8 2.8 1.7 2 0 0 2 2 2 1 PAN domain Aldedh PF00171.22 CDJ92433.1 - 2.7e-95 319.6 0.3 4.9e-95 318.7 0.3 1.4 2 0 0 2 2 2 1 Aldehyde dehydrogenase family Lipase_3 PF01764.25 CDJ92433.1 - 4.7e-15 55.7 0.0 1.2e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Peptidase_C92 PF05708.12 CDJ92433.1 - 7e-15 55.5 0.0 1.2e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Hydrolase_4 PF12146.8 CDJ92433.1 - 0.029 13.7 0.0 0.06 12.6 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Cucumo_coat PF00760.18 CDJ92433.1 - 0.15 11.7 0.1 0.37 10.4 0.1 1.6 1 0 0 1 1 1 0 Cucumovirus coat protein Solute_trans_a PF03619.16 CDJ92434.1 - 5.8e-57 193.2 13.7 9.1e-49 166.4 6.3 2.0 1 1 1 2 2 2 2 Organic solute transporter Ostalpha FAM110_C PF14160.6 CDJ92435.1 - 1.2e-06 29.5 0.6 3.2e-06 28.2 0.6 1.8 1 1 0 1 1 1 1 Centrosome-associated C terminus DSPc PF00782.20 CDJ92436.1 - 8.4e-12 45.1 0.1 2.5e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDJ92436.1 - 2e-08 34.1 0.1 3.4e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CDJ92436.1 - 0.00081 19.4 0.1 0.0017 18.4 0.1 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CDJ92436.1 - 0.0014 18.8 0.0 0.0031 17.6 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 CDJ92436.1 - 0.097 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) HA1 PF18239.1 CDJ92436.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Hemagglutinin I Retrotran_gag_2 PF14223.6 CDJ92437.1 - 0.006 16.3 0.6 3.7 7.2 0.0 2.5 3 0 0 3 3 3 2 gag-polypeptide of LTR copia-type Erf4 PF10256.9 CDJ92439.1 - 7.6e-28 96.9 0.1 8.9e-28 96.7 0.1 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family RuBisCO_small PF00101.20 CDJ92440.1 - 0.096 12.7 0.5 0.19 11.8 0.5 1.4 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain Glyco_transf_43 PF03360.16 CDJ92441.1 - 2.6e-44 151.5 0.0 3.1e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 7tm_1 PF00001.21 CDJ92443.1 - 2.6e-47 161.4 26.8 3.4e-47 161.0 26.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 CDJ92443.1 - 1e-10 41.8 14.7 1e-10 41.8 14.7 2.0 1 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 CDJ92443.1 - 7.6e-05 22.2 33.4 0.00013 21.4 12.1 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 CDJ92443.1 - 0.00013 21.7 24.9 0.00013 21.7 24.9 3.2 1 1 2 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2688 PF10892.8 CDJ92443.1 - 0.16 11.4 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) AA_permease_2 PF13520.6 CDJ92444.1 - 1.1e-44 153.0 49.7 1.6e-44 152.4 49.8 1.2 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CDJ92444.1 - 9.1e-17 60.8 41.1 9.1e-17 60.8 41.1 1.6 1 1 0 1 1 1 1 Amino acid permease GYF PF02213.16 CDJ92445.1 - 1.4e-12 47.1 0.3 2.8e-12 46.1 0.3 1.5 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 CDJ92445.1 - 0.19 11.5 0.0 0.19 11.5 0.0 2.4 3 0 0 3 3 3 0 GYF domain 2 VWA PF00092.28 CDJ92446.1 - 5.8e-05 23.4 4.8 0.046 14.0 0.2 3.4 4 1 0 4 4 4 2 von Willebrand factor type A domain DUF938 PF06080.12 CDJ92449.1 - 1.5e-65 220.8 0.0 1.8e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_4 PF02390.17 CDJ92449.1 - 0.00013 21.5 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.6 CDJ92449.1 - 0.033 14.0 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_M99_m PF17130.4 CDJ92449.1 - 0.076 13.0 0.0 0.43 10.5 0.0 2.2 2 1 0 2 2 2 0 beta-barrel domain of carboxypeptidase M99 Methyltransf_25 PF13649.6 CDJ92449.1 - 0.11 13.2 0.0 0.2 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Sulfotransfer_2 PF03567.14 CDJ92450.1 - 1.8e-50 172.2 1.8 2.4e-50 171.8 1.8 1.2 1 0 0 1 1 1 1 Sulfotransferase family DUF769 PF05590.11 CDJ92450.1 - 0.14 11.6 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Xylella fastidiosa protein of unknown function (DUF769) TbpB_A PF17484.2 CDJ92450.1 - 0.18 12.5 0.9 0.55 11.0 1.0 1.7 1 1 0 1 1 1 0 N-Lobe handle Tf-binding protein B MRG PF05712.13 CDJ92451.1 - 3.4e-34 117.9 0.0 4.2e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 MRG RVT_1 PF00078.27 CDJ92452.1 - 5.1e-54 183.1 0.6 9.3e-28 97.3 0.1 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDJ92452.1 - 1.3e-33 115.0 0.0 5.2e-33 113.1 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ92452.1 - 1.5e-33 115.2 0.0 6.4e-33 113.2 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 CDJ92452.1 - 0.00022 21.1 5.2 0.0015 18.5 1.4 2.5 2 0 0 2 2 2 1 Zinc knuckle gag-asp_proteas PF13975.6 CDJ92452.1 - 0.0012 19.4 0.0 0.0038 17.8 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RTP1_C1 PF10363.9 CDJ92452.1 - 0.0043 17.2 0.3 16 5.7 0.0 3.4 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 Asp_protease_2 PF13650.6 CDJ92452.1 - 0.054 14.1 0.0 0.26 12.0 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease DivIC PF04977.15 CDJ92452.1 - 0.19 11.5 1.9 0.98 9.2 0.6 2.8 2 0 0 2 2 2 0 Septum formation initiator Collagen PF01391.18 CDJ92454.1 - 1.1e-18 66.8 107.2 1.3e-07 31.3 42.2 4.1 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ92454.1 - 2.7e-15 56.2 0.1 3.9e-15 55.6 0.1 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain DUF5105 PF17118.5 CDJ92455.1 - 0.016 15.0 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5105) Guanylate_cyc PF00211.20 CDJ92456.1 - 9.8e-31 106.8 0.0 1.5e-19 70.3 0.0 2.1 1 1 1 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain CAF1 PF04857.20 CDJ92458.1 - 0.0057 15.9 0.1 0.007 15.6 0.1 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease UDPGP PF01704.18 CDJ92460.1 - 4.8e-192 638.1 0.0 5.6e-192 637.9 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase FG-GAP_2 PF14312.6 CDJ92460.1 - 0.18 12.1 0.1 0.35 11.1 0.1 1.4 1 0 0 1 1 1 0 FG-GAP repeat Fringe PF02434.16 CDJ92462.1 - 0.00042 19.8 0.0 0.00058 19.4 0.0 1.2 1 0 0 1 1 1 1 Fringe-like F-box PF00646.33 CDJ92463.1 - 0.014 15.3 0.0 0.045 13.7 0.0 1.8 1 0 0 1 1 1 0 F-box domain zf-CCHC PF00098.23 CDJ92465.1 - 0.15 12.2 10.7 0.28 11.3 1.2 2.9 2 1 0 2 2 2 0 Zinc knuckle RT_RNaseH_2 PF17919.1 CDJ92466.1 - 2.4e-35 120.6 0.0 1.4e-34 118.1 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ92466.1 - 1.7e-31 108.6 0.0 5.9e-31 106.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ92466.1 - 4.3e-19 68.9 0.0 1.1e-18 67.6 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ92466.1 - 2.7e-15 56.2 0.0 8.4e-15 54.6 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CDJ92466.1 - 0.00013 22.1 0.1 0.00059 20.0 0.1 2.3 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 CDJ92467.1 - 2.8e-05 23.8 0.4 0.00027 20.7 0.0 2.6 3 0 0 3 3 3 1 Integrase core domain rve PF00665.26 CDJ92467.1 - 0.0022 18.2 0.0 0.0067 16.6 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain 7TM_GPCR_Srw PF10324.9 CDJ92470.1 - 0.0016 17.8 0.9 0.0018 17.6 0.9 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw C2 PF00168.30 CDJ92471.1 - 6.2e-40 135.7 0.0 5.8e-27 94.0 0.0 2.3 2 0 0 2 2 2 2 C2 domain SMP_LBD PF17047.5 CDJ92471.1 - 1.4e-35 122.4 0.0 2.2e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain NT-C2 PF10358.9 CDJ92471.1 - 0.16 11.7 0.0 0.45 10.2 0.0 1.7 2 0 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins GST_N_4 PF17172.4 CDJ92472.1 - 3.7e-15 56.5 0.0 5e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N_3 PF13417.6 CDJ92472.1 - 7.7e-06 26.2 0.0 2.5e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 CDJ92472.1 - 0.018 15.2 0.1 0.073 13.3 0.1 2.1 1 1 0 1 1 1 0 Glutaredoxin DUF2650 PF10853.8 CDJ92473.1 - 3.5e-18 65.0 3.8 3.5e-18 65.0 3.8 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2650) Pkinase PF00069.25 CDJ92474.1 - 4.1e-59 200.1 0.0 5.5e-59 199.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ92474.1 - 1.3e-30 106.5 0.0 1.6e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ92474.1 - 1e-06 28.2 0.0 1.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDJ92474.1 - 0.00018 20.5 0.1 0.00063 18.8 0.1 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CDJ92474.1 - 0.00032 20.1 0.0 0.0015 17.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CDJ92474.1 - 0.00065 19.7 0.1 0.029 14.3 0.1 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 CDJ92474.1 - 0.031 13.9 0.1 2 8.0 0.1 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 CDJ92474.1 - 0.067 12.8 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 RIO1 family GCV_T PF01571.21 CDJ92475.1 - 1.9e-09 37.3 0.0 2.7e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DUF3626 PF12294.8 CDJ92475.1 - 0.067 12.2 0.0 0.091 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) Dsh_C PF12316.8 CDJ92476.1 - 0.081 13.3 3.9 0.11 12.9 3.9 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Nop53 PF07767.11 CDJ92476.1 - 0.12 11.8 23.2 0.15 11.4 23.2 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Raftlin PF15250.6 CDJ92476.1 - 0.14 10.9 7.2 0.14 10.8 7.2 1.1 1 0 0 1 1 1 0 Raftlin RNA_polI_A34 PF08208.11 CDJ92476.1 - 0.38 10.8 21.1 0.49 10.5 21.1 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3591 PF12157.8 CDJ92476.1 - 0.66 8.6 10.0 0.85 8.2 10.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3591) TFIIF_alpha PF05793.12 CDJ92476.1 - 1.4 7.5 23.0 2 6.9 23.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ALMT PF11744.8 CDJ92476.1 - 3.7 6.3 9.8 3.9 6.2 9.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter NARP1 PF12569.8 CDJ92476.1 - 3.9 6.3 14.6 4.9 6.0 14.6 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Presenilin PF01080.17 CDJ92476.1 - 5.9 5.5 12.4 7 5.3 12.4 1.2 1 0 0 1 1 1 0 Presenilin RVT_1 PF00078.27 CDJ92477.1 - 5e-36 124.3 0.0 8.3e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ephrin PF00812.17 CDJ92477.1 - 1.3e-28 99.7 0.0 1.9e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Ephrin TcpQ PF10671.9 CDJ92477.1 - 0.076 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q Collagen PF01391.18 CDJ92478.1 - 9e-17 60.6 56.6 0.00056 19.6 56.6 2.9 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Flavi_NS2B PF01002.19 CDJ92479.1 - 2.1 8.2 5.5 13 5.6 0.8 2.3 2 0 0 2 2 2 0 Flavivirus non-structural protein NS2B DM PF00751.18 CDJ92480.1 - 5.7e-22 77.4 13.2 9e-22 76.7 13.2 1.3 1 0 0 1 1 1 1 DM DNA binding domain DMA PF03474.14 CDJ92480.1 - 1.5e-10 40.5 0.1 3.4e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 DMRTA motif DUF16 PF01519.16 CDJ92481.1 - 0.28 11.7 4.2 0.58 10.7 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 OSTMP1 PF09777.9 CDJ92482.1 - 8.5e-61 205.3 12.1 1.1e-60 205.0 12.1 1.0 1 0 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor zf-AD PF07776.15 CDJ92482.1 - 0.1 12.9 4.1 7 7.0 0.2 2.7 2 1 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Fer2_3 PF13085.6 CDJ92483.1 - 6.9e-33 112.9 0.0 1.2e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 CDJ92483.1 - 1.4e-09 38.3 6.0 1.4e-09 38.3 6.0 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CDJ92483.1 - 1.2e-07 32.1 6.1 1.2e-07 32.1 6.1 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 CDJ92483.1 - 5.9e-07 29.5 3.5 5.9e-07 29.5 3.5 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 CDJ92483.1 - 0.0005 20.0 0.3 0.0005 20.0 0.3 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 CDJ92483.1 - 0.0068 17.0 13.7 0.011 16.3 7.2 2.8 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 CDJ92483.1 - 0.012 15.7 7.2 0.012 15.7 7.2 2.6 2 2 0 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 CDJ92483.1 - 0.027 14.6 0.7 1.3 9.3 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain fn1 PF00039.18 CDJ92484.1 - 6.3 7.1 14.2 6.5 7.0 2.4 3.7 3 0 0 3 3 3 0 Fibronectin type I domain PAPS_reduct PF01507.19 CDJ92485.1 - 1.6e-18 67.3 0.0 2.9e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family WD40 PF00400.32 CDJ92485.1 - 3.7e-16 59.2 9.7 0.00033 21.4 0.3 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat KOG2701 PF09762.9 CDJ92486.1 - 9.2e-52 175.8 0.0 9.2e-52 175.8 0.0 3.5 3 1 0 3 3 3 1 Coiled-coil domain-containing protein (DUF2037) MscS_porin PF12795.7 CDJ92486.1 - 0.0046 16.5 39.3 0.0096 15.5 15.7 3.2 2 1 1 3 3 3 2 Mechanosensitive ion channel porin domain DUF1664 PF07889.12 CDJ92486.1 - 0.031 14.3 21.5 0.5 10.4 1.8 4.8 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 CDJ92486.1 - 2.6 8.6 11.8 22 5.6 0.6 4.4 4 2 0 4 4 4 0 Nucleopolyhedrovirus P10 protein T3SchapCesA PF11439.8 CDJ92486.1 - 8.7 6.6 23.8 0.054 13.6 5.2 4.5 3 1 1 4 4 4 0 Type III secretion system filament chaperone CesA G-alpha PF00503.20 CDJ92487.1 - 5.4e-92 308.7 8.8 6.6e-92 308.4 8.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDJ92487.1 - 5.2e-13 48.8 0.6 2.3e-08 33.7 0.1 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ92487.1 - 0.002 17.5 1.9 0.073 12.4 0.3 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 CDJ92487.1 - 0.0044 16.6 0.2 0.023 14.2 0.1 2.1 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 CDJ92487.1 - 0.0089 15.8 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CDJ92487.1 - 0.011 15.4 0.1 0.032 14.0 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 CDJ92487.1 - 0.02 15.1 0.1 2.9 8.2 0.0 2.7 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FlhC PF05280.11 CDJ92487.1 - 0.021 14.5 0.1 0.046 13.4 0.1 1.5 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) ATP_bind_1 PF03029.17 CDJ92487.1 - 0.026 14.3 0.9 2.1 8.1 0.1 2.5 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 CDJ92487.1 - 0.031 14.7 0.3 0.5 10.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 CDJ92487.1 - 0.036 14.3 0.0 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CDJ92487.1 - 0.045 14.3 0.0 0.15 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CDJ92487.1 - 0.048 13.8 0.1 4.5 7.4 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.29 CDJ92487.1 - 0.052 14.0 0.1 7.3 7.0 0.0 3.0 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) Ras PF00071.22 CDJ92487.1 - 0.057 13.0 0.9 1.5 8.4 0.2 2.9 2 1 0 2 2 2 0 Ras family AAA_16 PF13191.6 CDJ92487.1 - 0.058 13.8 0.0 0.15 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Sigma54_activ_2 PF14532.6 CDJ92487.1 - 0.073 13.2 0.0 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 CDJ92487.1 - 0.077 13.3 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 CDJ92487.1 - 0.087 12.0 0.4 0.23 10.6 0.2 1.7 1 1 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 FtsK_SpoIIIE PF01580.18 CDJ92487.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 CDJ92487.1 - 0.14 12.7 0.8 0.29 11.6 0.4 1.9 1 1 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.21 CDJ92487.1 - 0.17 11.2 0.0 0.64 9.4 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI GTP_EFTU PF00009.27 CDJ92487.1 - 0.31 10.6 1.4 1 8.8 0.2 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain p450 PF00067.22 CDJ92488.1 - 2.3e-27 95.9 0.0 2.6e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 CDJ92489.1 - 3.4e-73 247.0 0.0 4e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Retrotrans_gag PF03732.17 CDJ92491.1 - 1.6e-05 25.1 0.1 0.00032 20.9 0.0 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 CDJ92491.1 - 0.00011 22.1 1.3 0.00019 21.4 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 CDJ92491.1 - 0.0018 18.1 2.2 0.003 17.4 2.2 1.3 1 0 0 1 1 1 1 Zinc knuckle Not1 PF04054.15 CDJ92491.1 - 0.064 12.2 0.1 0.096 11.6 0.1 1.2 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 rve PF00665.26 CDJ92492.1 - 1.2e-15 57.7 0.0 4.9e-15 55.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 CDJ92492.1 - 0.0047 16.7 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain MDH PF02315.16 CDJ92492.1 - 0.17 12.0 0.3 0.45 10.6 0.3 1.7 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit SCVP PF17619.2 CDJ92493.1 - 4.8e-42 142.7 5.3 2.1e-23 83.0 1.4 2.2 2 0 0 2 2 2 2 Secreted clade V proteins SCVP PF17619.2 CDJ92494.1 - 1e-33 116.1 4.3 8e-23 81.1 1.9 2.1 2 0 0 2 2 2 2 Secreted clade V proteins CdiI_4 PF18624.1 CDJ92494.1 - 0.0087 16.5 0.8 0.019 15.4 0.2 1.9 1 1 1 2 2 2 1 CDI immunity protein DUF866 PF05907.13 CDJ92494.1 - 0.0093 15.9 0.2 0.39 10.6 0.1 2.1 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF866) ABC2_membrane_3 PF12698.7 CDJ92495.1 - 3.7e-30 105.2 5.5 5.5e-30 104.6 5.5 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 CDJ92496.1 - 1e-29 103.8 0.1 1.7e-29 103.1 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CDJ92496.1 - 1e-08 35.4 1.0 0.00031 20.7 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDJ92496.1 - 0.00036 20.0 0.5 0.38 10.1 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CDJ92496.1 - 0.0096 15.6 0.1 0.03 14.0 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 CDJ92496.1 - 0.048 14.1 5.7 0.069 13.6 3.8 2.3 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CDJ92496.1 - 0.071 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 CDJ92496.1 - 0.12 12.5 0.1 0.31 11.2 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase C1_1 PF00130.22 CDJ92497.1 - 9.7e-31 105.4 20.0 2.6e-15 56.0 9.2 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 CDJ92497.1 - 8.8e-07 29.2 18.7 1.7e-05 25.0 3.5 2.6 2 0 0 2 2 2 2 C1 domain PH PF00169.29 CDJ92497.1 - 3.4e-06 27.5 0.6 3.4e-06 27.5 0.6 2.0 2 0 0 2 2 2 1 PH domain PHD PF00628.29 CDJ92497.1 - 0.0061 16.4 18.7 0.28 11.1 3.1 2.6 2 0 0 2 2 2 2 PHD-finger zf-RING_9 PF13901.6 CDJ92497.1 - 0.008 16.2 18.5 0.027 14.5 1.6 2.6 3 0 0 3 3 3 2 Putative zinc-RING and/or ribbon FYVE_2 PF02318.16 CDJ92497.1 - 0.32 11.2 13.0 0.12 12.6 3.7 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger Zf_RING PF16744.5 CDJ92497.1 - 0.47 10.6 12.9 4.7 7.4 4.4 2.9 3 0 0 3 3 3 0 KIAA1045 RING finger Prok-RING_1 PF14446.6 CDJ92497.1 - 1.8 8.6 16.5 0.25 11.3 1.6 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 CH PF00307.31 CDJ92498.1 - 4.5e-38 129.8 1.7 1.2e-21 77.0 1.3 2.1 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CDJ92498.1 - 2.1e-06 27.5 0.0 0.0019 18.0 0.0 2.5 2 1 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 CDJ92498.1 - 5.6e-06 26.4 1.5 0.071 13.2 0.0 2.2 2 0 0 2 2 2 2 CH-like domain in sperm protein Insulin PF00049.18 CDJ92499.1 - 0.0036 18.3 3.9 0.036 15.1 3.9 2.0 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family E3_UbLigase_EDD PF11547.8 CDJ92499.1 - 0.05 13.3 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD Cohesin_load PF10345.9 CDJ92500.1 - 2.2e-10 39.6 5.7 3.6e-10 38.9 5.7 1.3 1 0 0 1 1 1 1 Cohesin loading factor TPR_14 PF13428.6 CDJ92500.1 - 0.0031 18.2 0.2 3 8.9 0.0 4.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ92500.1 - 0.01 16.1 12.2 0.56 10.5 0.3 5.7 6 1 1 7 7 7 2 Tetratricopeptide repeat DUF410 PF04190.13 CDJ92500.1 - 0.029 14.2 0.3 0.18 11.6 0.0 2.4 3 1 0 3 3 3 0 Protein of unknown function (DUF410) GNT-I PF03071.15 CDJ92500.1 - 0.1 11.3 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 GNT-I family PID PF00640.23 CDJ92501.1 - 1.5e-41 141.7 0.9 3.5e-41 140.5 0.9 1.6 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.24 CDJ92501.1 - 8.4e-27 93.4 3.2 1.1e-12 48.2 0.3 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CDJ92501.1 - 6.2e-10 38.8 1.4 1.4e-05 24.8 0.2 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CDJ92501.1 - 0.003 17.8 0.1 0.083 13.2 0.0 2.5 2 0 0 2 2 2 1 PDZ domain NRho PF16733.5 CDJ92501.1 - 0.024 14.7 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 Rhomboid N-terminal domain CH PF00307.31 CDJ92502.1 - 5.4e-23 81.2 0.2 6.9e-23 80.9 0.2 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CDJ92502.1 - 0.014 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain CDC24 PF06395.11 CDJ92502.1 - 0.016 15.5 0.1 0.025 14.8 0.1 1.3 1 0 0 1 1 1 0 CDC24 Calponin Phospho_p8 PF10195.9 CDJ92502.1 - 0.065 13.7 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 DNA-binding nuclear phosphoprotein p8 AAA_12 PF13087.6 CDJ92503.1 - 9.3e-35 120.1 0.0 1.7e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ92503.1 - 1e-09 38.4 0.1 7.2e-05 22.6 0.5 2.8 2 1 0 2 2 2 2 AAA domain AAA_11 PF13086.6 CDJ92503.1 - 1e-08 35.3 0.0 2.1e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ92503.1 - 6.6e-06 26.5 0.0 1.9e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CDJ92503.1 - 6.4e-05 22.8 0.0 0.00034 20.4 0.0 2.1 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 CDJ92503.1 - 0.00012 22.0 0.1 0.0057 16.5 0.1 2.3 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 CDJ92503.1 - 0.0012 18.6 0.0 0.0032 17.2 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ResIII PF04851.15 CDJ92503.1 - 0.003 17.6 0.0 0.0063 16.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF5051 PF16473.5 CDJ92503.1 - 0.18 11.8 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease, RNase T-like G-alpha PF00503.20 CDJ92504.1 - 2.6e-86 290.0 0.6 3.2e-86 289.7 0.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDJ92504.1 - 1.1e-10 41.2 1.0 9.1e-07 28.5 0.1 3.0 3 1 0 3 3 3 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ92504.1 - 0.027 14.6 0.0 4.1 7.5 0.0 2.5 1 1 0 2 2 2 0 50S ribosome-binding GTPase Roc PF08477.13 CDJ92504.1 - 0.04 14.1 0.3 1.8 8.8 0.1 2.6 1 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 CDJ92504.1 - 0.071 12.5 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 CDJ92504.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CDJ92504.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 CDJ92504.1 - 0.22 10.9 1.1 11 5.3 0.2 2.5 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region Ribosomal_L27e PF01777.18 CDJ92505.1 - 8.7e-32 109.3 8.9 8.7e-32 109.3 8.9 2.0 2 0 0 2 2 2 1 Ribosomal L27e protein family MMR_HSR1 PF01926.23 CDJ92505.1 - 2.1e-17 63.2 0.2 5.9e-15 55.3 0.0 3.0 3 1 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ92505.1 - 7.9e-09 35.2 0.1 3.1e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CDJ92505.1 - 1.7e-06 28.1 1.7 0.0007 19.5 0.2 3.1 2 1 0 2 2 2 1 RsgA GTPase KOW PF00467.29 CDJ92505.1 - 4.2e-05 23.3 2.7 5.1e-05 23.1 0.5 2.3 2 0 0 2 2 2 1 KOW motif cobW PF02492.19 CDJ92505.1 - 0.032 13.8 0.0 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.16 CDJ92505.1 - 0.045 13.1 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 AIG1 family W2 PF02020.18 CDJ92505.1 - 0.26 11.5 4.6 0.92 9.7 0.3 3.0 3 0 0 3 3 3 0 eIF4-gamma/eIF5/eIF2-epsilon WD40 PF00400.32 CDJ92506.1 - 3.1e-15 56.3 4.4 0.00083 20.1 0.0 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ92506.1 - 9.3e-14 51.5 0.0 3.9e-05 23.9 0.0 5.2 3 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 CDJ92506.1 - 6.3e-08 32.4 0.2 0.019 14.9 0.0 3.8 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 CDJ92506.1 - 8.6e-05 22.5 0.1 0.32 10.9 0.0 3.8 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CDJ92506.1 - 9.8e-05 21.5 0.0 0.49 9.3 0.0 3.0 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 CDJ92506.1 - 0.011 14.8 0.0 1.8 7.5 0.0 2.5 2 0 0 2 2 2 0 Coatomer WD associated region SGL PF08450.12 CDJ92506.1 - 0.064 12.8 0.1 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Cytochrom_D1 PF02239.16 CDJ92506.1 - 0.082 11.4 0.0 0.18 10.3 0.0 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain DPPIV_N PF00930.21 CDJ92506.1 - 0.15 10.8 0.2 4.8 5.8 0.0 2.7 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region LIM PF00412.22 CDJ92507.1 - 3e-22 78.6 29.8 2.1e-12 47.1 9.6 2.2 2 0 0 2 2 2 2 LIM domain zf-dskA_traR PF01258.17 CDJ92507.1 - 0.028 14.3 0.7 0.028 14.3 0.7 5.1 4 2 1 5 5 5 0 Prokaryotic dksA/traR C4-type zinc finger zf-met PF12874.7 CDJ92507.1 - 0.59 10.6 17.6 9.9 6.7 0.4 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Fibrinogen_BP PF08017.11 CDJ92508.1 - 2.4e-05 22.9 21.4 2.4e-05 22.9 21.4 2.1 1 1 1 2 2 2 1 Fibrinogen binding protein DUF1664 PF07889.12 CDJ92509.1 - 0.00098 19.2 2.0 0.0015 18.6 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) EGF PF00008.27 CDJ92509.1 - 0.013 15.8 5.7 0.013 15.8 5.7 1.9 1 1 0 1 1 1 0 EGF-like domain Exonuc_VII_L PF02601.15 CDJ92509.1 - 0.014 15.0 0.5 0.017 14.7 0.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DASH_Duo1 PF08651.10 CDJ92509.1 - 0.022 14.5 1.5 0.044 13.6 1.5 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 TMPIT PF07851.13 CDJ92509.1 - 0.074 12.3 2.7 0.1 11.9 2.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein UPF0242 PF06785.11 CDJ92509.1 - 0.077 13.1 4.5 0.11 12.5 4.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Dicty_REP PF05086.12 CDJ92509.1 - 0.083 10.9 9.6 0.11 10.4 9.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NPV_P10 PF05531.12 CDJ92509.1 - 0.13 12.8 2.4 0.26 11.8 2.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF5082 PF16888.5 CDJ92509.1 - 0.2 11.9 5.1 0.37 11.1 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) FOLN PF09289.10 CDJ92509.1 - 0.28 11.4 3.5 0.71 10.1 3.5 1.7 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain RAP1 PF07218.11 CDJ92509.1 - 0.29 9.4 2.2 0.4 8.9 2.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Sec2p PF06428.11 CDJ92509.1 - 0.49 10.4 8.7 0.58 10.2 7.7 1.5 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p FlaC_arch PF05377.11 CDJ92509.1 - 0.52 10.7 2.6 2 8.8 0.3 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 CDJ92510.1 - 0.00098 19.2 2.0 0.0015 18.6 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) EGF PF00008.27 CDJ92510.1 - 0.013 15.8 5.7 0.013 15.8 5.7 1.9 1 1 0 1 1 1 0 EGF-like domain Exonuc_VII_L PF02601.15 CDJ92510.1 - 0.014 15.0 0.5 0.017 14.7 0.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DASH_Duo1 PF08651.10 CDJ92510.1 - 0.022 14.5 1.5 0.044 13.6 1.5 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 TMPIT PF07851.13 CDJ92510.1 - 0.074 12.3 2.7 0.1 11.9 2.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein UPF0242 PF06785.11 CDJ92510.1 - 0.077 13.1 4.5 0.11 12.5 4.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Dicty_REP PF05086.12 CDJ92510.1 - 0.083 10.9 9.6 0.11 10.4 9.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NPV_P10 PF05531.12 CDJ92510.1 - 0.13 12.8 2.4 0.26 11.8 2.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF5082 PF16888.5 CDJ92510.1 - 0.2 11.9 5.1 0.37 11.1 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) FOLN PF09289.10 CDJ92510.1 - 0.28 11.4 3.5 0.71 10.1 3.5 1.7 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain RAP1 PF07218.11 CDJ92510.1 - 0.29 9.4 2.2 0.4 8.9 2.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Sec2p PF06428.11 CDJ92510.1 - 0.49 10.4 8.7 0.58 10.2 7.7 1.5 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p FlaC_arch PF05377.11 CDJ92510.1 - 0.52 10.7 2.6 2 8.8 0.3 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) gag-asp_proteas PF13975.6 CDJ92511.1 - 0.00012 22.6 0.1 0.0008 19.9 0.0 2.4 1 1 1 2 2 2 1 gag-polyprotein putative aspartyl protease DUF2452 PF10504.9 CDJ92511.1 - 0.0012 18.3 0.4 0.0035 16.8 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) zf-C2H2_10 PF16588.5 CDJ92511.1 - 0.0027 17.4 0.9 0.0062 16.2 0.9 1.6 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC PF00098.23 CDJ92511.1 - 0.013 15.6 1.2 0.033 14.3 1.2 1.7 1 0 0 1 1 1 0 Zinc knuckle PikAIV_N PF18605.1 CDJ92511.1 - 0.036 13.6 1.8 0.12 11.9 0.1 2.7 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain CCM2_C PF16545.5 CDJ92511.1 - 0.12 12.9 0.1 0.36 11.4 0.1 1.8 1 0 0 1 1 1 0 Cerebral cavernous malformation protein, harmonin-homology RVP PF00077.20 CDJ92511.1 - 0.18 12.2 0.0 0.72 10.2 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease Kringle PF00051.18 CDJ92513.1 - 0.00031 21.0 2.5 0.0023 18.2 0.7 2.7 2 1 0 2 2 2 1 Kringle domain Guanylate_kin PF00625.21 CDJ92514.1 - 2.1e-42 144.9 0.0 1e-41 142.6 0.0 2.1 2 0 0 2 2 2 1 Guanylate kinase PDZ PF00595.24 CDJ92514.1 - 1.6e-21 76.4 0.9 1.6e-11 44.4 0.2 2.9 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 CDJ92514.1 - 6.6e-21 73.9 0.4 3.5e-10 39.6 0.0 2.9 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CDJ92514.1 - 3.2e-11 43.4 0.3 0.00036 20.8 0.0 2.7 2 0 0 2 2 2 2 PDZ domain SH3_2 PF07653.17 CDJ92514.1 - 9.2e-11 41.3 0.0 3e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDJ92514.1 - 3.8e-06 26.4 1.0 1.7e-05 24.3 1.0 2.1 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CDJ92514.1 - 0.00072 19.4 0.1 0.002 18.0 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain MT PF12777.7 CDJ92514.1 - 0.052 12.6 0.2 0.091 11.8 0.2 1.3 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor PDZ_4 PF17816.1 CDJ92514.1 - 0.078 13.4 2.6 9.4 6.7 0.0 3.8 2 2 1 4 4 4 0 PDZ domain BPL_N PF09825.9 CDJ92514.1 - 0.11 11.6 1.4 0.22 10.6 1.4 1.4 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal MnmE_helical PF12631.7 CDJ92514.1 - 0.26 11.4 4.4 0.83 9.8 4.4 1.9 1 1 0 1 1 1 0 MnmE helical domain Slu7 PF11708.8 CDJ92515.1 - 6.6e-93 311.3 6.8 6.6e-93 311.3 6.8 4.3 3 2 1 4 4 4 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC PF00098.23 CDJ92515.1 - 3.2e-05 23.8 2.5 5.6e-05 23.0 2.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ92515.1 - 0.15 11.8 1.1 0.36 10.6 1.1 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF3446 PF11928.8 CDJ92515.1 - 1.3 9.4 11.6 1.6 9.1 4.6 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain Spem1 PF15670.5 CDJ92515.1 - 3.9 7.0 14.6 12 5.4 14.6 1.8 1 0 0 1 1 1 0 Spermatid maturation protein 1 Dsh_C PF12316.8 CDJ92515.1 - 5 7.5 17.7 13 6.1 17.7 1.8 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SR-25 PF10500.9 CDJ92515.1 - 9.2 5.8 60.8 0.58 9.7 36.9 3.0 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein AAA_12 PF13087.6 CDJ92516.1 - 2e-33 115.7 0.0 3.9e-33 114.7 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CDJ92516.1 - 1.4e-08 35.1 0.5 2.7e-07 31.0 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CDJ92516.1 - 1.8e-06 27.8 0.0 0.0088 15.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain Helicase_RecD PF05127.14 CDJ92516.1 - 6.2e-06 26.2 0.1 0.03 14.2 0.0 3.3 3 0 0 3 3 3 2 Helicase Viral_helicase1 PF01443.18 CDJ92516.1 - 0.00014 21.7 0.0 0.019 14.7 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 CDJ92516.1 - 0.00018 21.4 0.1 0.00048 20.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CDJ92516.1 - 0.004 16.9 0.0 0.012 15.4 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DEAD PF00270.29 CDJ92516.1 - 0.0065 16.3 0.6 0.36 10.6 0.6 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.16 CDJ92516.1 - 0.009 15.5 0.2 0.81 9.1 0.4 3.0 3 0 0 3 3 3 1 PhoH-like protein ResIII PF04851.15 CDJ92516.1 - 0.09 12.8 0.8 0.49 10.4 0.8 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Myosin_head PF00063.21 CDJ92517.1 - 3.1e-296 984.1 3.5 3.9e-296 983.8 3.5 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 CDJ92517.1 - 3e-16 59.0 2.8 6.1e-16 58.0 2.8 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_23 PF13476.6 CDJ92517.1 - 0.0058 17.2 5.2 2.6 8.5 5.9 2.9 2 0 0 2 2 2 1 AAA domain Leu_zip PF15294.6 CDJ92517.1 - 0.016 14.7 8.2 0.036 13.6 8.2 1.5 1 0 0 1 1 1 0 Leucine zipper AAA_22 PF13401.6 CDJ92517.1 - 0.041 14.2 0.3 0.25 11.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CDJ92517.1 - 0.13 12.6 0.3 0.34 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain UPF0242 PF06785.11 CDJ92517.1 - 0.2 11.7 6.2 0.4 10.8 6.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus KASH_CCD PF14662.6 CDJ92517.1 - 0.26 11.1 10.7 0.51 10.1 10.7 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH ADIP PF11559.8 CDJ92517.1 - 0.31 11.1 7.1 0.65 10.1 7.1 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding RNA_binding PF01877.17 CDJ92517.1 - 0.61 10.4 2.9 0.88 9.9 1.0 2.3 2 0 0 2 2 2 0 RNA binding ATPase PF06745.13 CDJ92517.1 - 0.91 8.8 3.7 9.9 5.4 0.0 2.4 2 0 0 2 2 2 0 KaiC YabA PF06156.13 CDJ92517.1 - 3.1 8.5 6.4 11 6.7 6.4 1.9 1 0 0 1 1 1 0 Initiation control protein YabA DUF755 PF05501.11 CDJ92518.1 - 2.1 8.6 12.9 5.5 7.3 12.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF755) GCFC PF07842.12 CDJ92519.1 - 3.8e-09 36.6 0.0 0.00013 21.7 0.0 2.2 1 1 1 2 2 2 2 GC-rich sequence DNA-binding factor-like protein Pro_isomerase PF00160.21 CDJ92520.1 - 1.9e-34 119.3 0.1 4.5e-34 118.0 0.1 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 CDJ92520.1 - 4.8e-15 55.1 0.1 2.3e-14 52.9 0.1 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNARE PF05739.19 CDJ92520.1 - 8.7e-07 28.9 4.0 1.5e-06 28.1 0.9 2.5 2 0 0 2 2 2 1 SNARE domain RRM_5 PF13893.6 CDJ92520.1 - 0.046 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF948 PF06103.11 CDJ92520.1 - 0.22 11.8 3.0 0.86 9.9 0.7 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Peptidase_M26_C PF07580.14 CDJ92520.1 - 0.41 9.1 3.2 4.8 5.5 0.3 2.1 2 0 0 2 2 2 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region Baculo_PEP_C PF04513.12 CDJ92520.1 - 0.46 10.5 7.2 6.3 6.8 0.4 2.6 3 0 0 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CK2S PF15011.6 CDJ92520.1 - 1 9.3 6.5 0.36 10.7 0.9 2.4 2 0 0 2 2 2 0 Casein Kinase 2 substrate FUSC PF04632.12 CDJ92520.1 - 1.9 6.9 5.3 2.9 6.3 5.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3482 PF11981.8 CDJ92520.1 - 2.1 7.6 8.0 0.081 12.3 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) ATPase PF06745.13 CDJ92520.1 - 2.6 7.3 7.2 0.82 9.0 1.7 2.3 2 0 0 2 2 2 0 KaiC Z1 PF10593.9 CDJ92520.1 - 9.1 5.7 8.0 2.1 7.8 1.2 2.8 3 0 0 3 3 3 0 Z1 domain DUF1664 PF07889.12 CDJ92520.1 - 9.9 6.2 10.0 11 6.1 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) VWA PF00092.28 CDJ92522.1 - 2.1e-20 73.7 0.0 2.9e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Lectin_C PF00059.21 CDJ92522.1 - 5.5e-15 56.0 2.7 5.8e-15 56.0 1.2 1.8 2 0 0 2 2 2 1 Lectin C-type domain VWA_2 PF13519.6 CDJ92522.1 - 3.1e-11 43.9 0.1 5.3e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Sec23_trunk PF04811.15 CDJ92522.1 - 0.043 13.4 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain PDZ_6 PF17820.1 CDJ92523.1 - 1.3e-06 28.2 0.0 2.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CDJ92523.1 - 6e-05 23.3 0.0 0.00011 22.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ92523.1 - 0.00085 19.6 0.0 0.0016 18.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain DUF1213 PF06740.12 CDJ92524.1 - 0.11 13.2 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1213) DUF5356 PF17309.2 CDJ92525.1 - 4.6e-39 133.5 10.6 7.1e-39 132.9 10.6 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5356) C1_1 PF00130.22 CDJ92526.1 - 0.0059 16.5 2.9 0.0059 16.5 2.9 4.0 3 1 1 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 CDJ92526.1 - 0.014 15.2 7.6 0.014 15.2 7.6 3.9 2 2 2 4 4 4 0 PHD-finger Herpes_glycoH_C PF17488.2 CDJ92526.1 - 0.62 9.9 4.8 6.9 6.5 0.1 2.3 2 0 0 2 2 2 0 Herpesvirus glycoprotein H C-terminal domain Uso1_p115_C PF04871.13 CDJ92526.1 - 1.1 9.6 6.9 2.2 8.7 6.9 1.5 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region zf-RING_9 PF13901.6 CDJ92526.1 - 4.3 7.2 14.4 0.12 12.3 2.3 3.1 3 1 0 3 3 3 0 Putative zinc-RING and/or ribbon DUF1610 PF07754.11 CDJ92526.1 - 7.3 6.7 12.1 2.6 8.1 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) PI3_PI4_kinase PF00454.27 CDJ92527.1 - 1.1e-34 120.4 0.1 2.4e-31 109.5 0.0 2.1 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 CDJ92527.1 - 0.011 15.1 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) PI3Ka PF00613.20 CDJ92528.1 - 4.1e-23 81.8 0.0 9.5e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) CAP PF00188.26 CDJ92529.1 - 1.2e-12 48.8 0.6 1.7e-12 48.2 0.6 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ92529.1 - 0.021 15.1 0.8 0.051 13.9 0.8 1.8 1 1 0 1 1 1 0 Ancylostoma-associated secreted protein related COesterase PF00135.28 CDJ92530.1 - 4.3e-84 283.2 0.1 4.9e-83 279.7 0.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDJ92530.1 - 0.00016 21.6 0.4 0.0048 16.8 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ92530.1 - 0.00071 20.2 0.5 0.0023 18.6 0.2 1.9 1 1 0 2 2 2 1 Alpha/beta hydrolase family DUF4448 PF14610.6 CDJ92530.1 - 0.00071 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3188 PF11384.8 CDJ92530.1 - 0.0099 15.6 0.6 0.019 14.6 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3188) TMEM154 PF15102.6 CDJ92530.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family DAGAT PF03982.13 CDJ92531.1 - 1.5e-113 378.6 0.0 1.7e-113 378.4 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DAGAT PF03982.13 CDJ92532.1 - 8.6e-126 418.8 0.0 1e-125 418.6 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DAGAT PF03982.13 CDJ92533.1 - 2.5e-123 410.7 0.0 2.9e-123 410.5 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase EI24 PF07264.11 CDJ92533.1 - 0.079 13.2 0.9 0.15 12.3 0.9 1.3 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DAGAT PF03982.13 CDJ92534.1 - 8e-92 307.3 3.1 7.6e-49 166.2 0.1 2.0 2 0 0 2 2 2 2 Diacylglycerol acyltransferase Ground-like PF04155.18 CDJ92535.1 - 0.0021 18.7 0.2 0.0026 18.4 0.2 1.1 1 0 0 1 1 1 1 Ground-like domain RWD PF05773.22 CDJ92536.1 - 5.8e-22 78.2 2.2 5.8e-22 78.2 2.2 1.7 2 0 0 2 2 2 1 RWD domain DFRP_C PF16543.5 CDJ92536.1 - 1.2e-07 32.1 8.6 1.2e-07 32.1 8.6 2.2 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 DUF445 PF04286.12 CDJ92536.1 - 0.0015 18.4 4.8 0.0018 18.1 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF349 PF03993.12 CDJ92536.1 - 0.11 12.8 1.1 0.11 12.8 1.1 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) PB1 PF00564.24 CDJ92537.1 - 5.7e-15 55.0 0.0 1e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 PB1 domain PDZ PF00595.24 CDJ92537.1 - 4.2e-09 36.6 0.1 6.5e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDJ92537.1 - 2.4e-06 27.3 0.1 6.1e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 PDZ domain Fibrinogen_C PF00147.18 CDJ92538.1 - 1.9e-48 165.2 8.9 2.7e-48 164.7 8.9 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Lectin_C PF00059.21 CDJ92538.1 - 4.6e-10 40.2 6.7 4.6e-10 40.2 6.7 2.8 3 0 0 3 3 3 1 Lectin C-type domain Fibrinogen_C PF00147.18 CDJ92539.1 - 1.5e-14 54.3 0.4 1.8e-14 54.1 0.4 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain zf-C4 PF00105.18 CDJ92540.1 - 0.00033 21.0 0.6 0.00082 19.8 0.6 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) MRP-L27 PF09809.9 CDJ92540.1 - 0.096 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L27 Neur_chan_LBD PF02931.23 CDJ92541.1 - 1.5e-78 263.1 0.7 2.1e-78 262.7 0.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ92541.1 - 1.4e-74 251.1 0.9 2e-74 250.7 0.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Claudin_2 PF13903.6 CDJ92541.1 - 0.12 12.1 3.2 0.21 11.3 2.2 1.8 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF21 PF01595.20 CDJ92541.1 - 3.4 7.4 9.3 57 3.4 8.8 2.4 1 1 1 2 2 2 0 Cyclin M transmembrane N-terminal domain Fibrinogen_C PF00147.18 CDJ92542.1 - 9e-44 149.9 8.8 1e-43 149.7 8.8 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fibrinogen_C PF00147.18 CDJ92543.1 - 6.4e-44 150.4 6.0 6.4e-44 150.4 6.0 1.7 2 0 0 2 2 2 1 Fibrinogen beta and gamma chains, C-terminal globular domain Lectin_C PF00059.21 CDJ92543.1 - 1.2e-14 54.9 6.4 1.2e-14 54.9 6.4 2.6 3 0 0 3 3 3 1 Lectin C-type domain Fibrinogen_C PF00147.18 CDJ92544.1 - 9.7e-42 143.2 7.3 2e-41 142.2 7.3 1.5 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Lectin_C PF00059.21 CDJ92544.1 - 3e-11 44.0 6.2 3e-11 44.0 6.2 2.7 3 0 0 3 3 3 1 Lectin C-type domain Fibrinogen_C PF00147.18 CDJ92545.1 - 2.4e-42 145.3 7.7 3.4e-42 144.8 7.7 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Lectin_C PF00059.21 CDJ92545.1 - 2.2e-12 47.7 3.9 2.2e-12 47.7 3.9 2.1 2 0 0 2 2 2 1 Lectin C-type domain PDEase_I PF00233.19 CDJ92546.1 - 2.3e-80 269.7 1.5 3.5e-80 269.2 1.5 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.12 CDJ92546.1 - 2.1e-26 91.5 0.1 4.7e-26 90.4 0.1 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal Exonuc_VII_S PF02609.16 CDJ92546.1 - 0.019 15.0 0.1 0.047 13.7 0.1 1.6 1 0 0 1 1 1 0 Exonuclease VII small subunit DOMON PF03351.17 CDJ92547.1 - 7e-13 48.9 0.0 1.1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 CDJ92547.1 - 6e-10 39.4 3.8 6e-10 39.4 3.8 2.6 4 0 0 4 4 4 1 Eukaryotic cytochrome b561 DUF3325 PF11804.8 CDJ92547.1 - 0.028 14.6 1.3 0.028 14.6 1.3 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF3325) OAD_gamma PF04277.13 CDJ92547.1 - 0.042 14.4 9.1 0.089 13.4 0.0 4.3 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain PI3_PI4_kinase PF00454.27 CDJ92548.1 - 2.5e-39 135.6 0.5 2.4e-38 132.4 0.5 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Med8 PF10232.9 CDJ92548.1 - 1.5e-26 93.5 2.3 2.4e-26 92.8 2.3 1.3 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 PI3Ka PF00613.20 CDJ92548.1 - 2e-24 86.0 1.1 2.8e-24 85.6 0.1 1.7 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 CDJ92548.1 - 3.6e-18 65.8 0.0 7.4e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 CDJ92548.1 - 8.8e-16 58.0 0.1 9e-15 54.8 0.0 2.4 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain PI3K_p85B PF02192.16 CDJ92548.1 - 5.7e-13 48.4 0.1 1.4e-12 47.1 0.1 1.7 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain PPP1R35_C PF15503.6 CDJ92549.1 - 5.8e-07 29.4 1.4 8.5e-07 28.9 1.4 1.3 1 0 0 1 1 1 1 Protein phosphatase 1 regulatory subunit 35 C-terminus Ldt_C PF17969.1 CDJ92550.1 - 0.16 12.7 0.8 4.3 8.2 0.0 3.0 3 0 0 3 3 3 0 L,D-transpeptidase C-terminal domain Enkurin PF13864.6 CDJ92550.1 - 1.4 9.4 7.5 1.1 9.7 0.7 3.0 3 1 1 4 4 4 0 Calmodulin-binding Cep57_CLD_2 PF14197.6 CDJ92550.1 - 4.7 7.4 9.6 10 6.3 0.7 3.7 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 zf-RVT PF13966.6 CDJ92551.1 - 0.053 14.2 2.4 0.19 12.5 0.3 2.7 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase DUF1194 PF06707.11 CDJ92551.1 - 0.1 11.8 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) Enkurin PF13864.6 CDJ92551.1 - 5.9 7.4 7.1 2 8.9 0.5 3.0 3 0 0 3 3 3 0 Calmodulin-binding DC_STAMP PF07782.13 CDJ92552.1 - 1e-33 116.8 1.7 2.2e-33 115.7 1.7 1.6 1 0 0 1 1 1 1 DC-STAMP-like protein DUF1418 PF07214.12 CDJ92552.1 - 0.0072 16.2 0.5 0.0072 16.2 0.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1418) CEBP_ZZ PF16366.5 CDJ92552.1 - 0.18 12.1 9.3 0.48 10.7 9.3 1.7 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain TMEMspv1-c74-12 PF11044.8 CDJ92554.1 - 2.8 8.0 5.0 4.6 7.3 2.0 2.1 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein MFS_1 PF07690.16 CDJ92555.1 - 4.1e-44 151.0 46.7 4e-41 141.1 25.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FixP_N PF14715.6 CDJ92555.1 - 0.0092 15.7 3.9 0.61 9.9 0.2 2.7 2 0 0 2 2 2 2 N-terminal domain of cytochrome oxidase-cbb3, FixP SHP PF03579.13 CDJ92555.1 - 0.17 11.8 0.2 0.17 11.8 0.2 2.2 2 0 0 2 2 2 0 Small hydrophobic protein RVT_1 PF00078.27 CDJ92556.1 - 3.1e-19 69.4 0.0 5.6e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cation_ATPase_C PF00689.21 CDJ92557.1 - 2.6e-42 144.6 3.4 2.6e-42 144.6 3.4 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CDJ92557.1 - 3.9e-22 78.7 0.3 3.9e-22 78.7 0.3 3.8 5 0 0 5 5 5 2 E1-E2 ATPase Cation_ATPase PF13246.6 CDJ92557.1 - 1e-20 73.6 0.1 2.3e-20 72.5 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CDJ92557.1 - 1.4e-18 66.3 0.0 1.5e-17 63.0 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus ATP_Ca_trans_C PF12424.8 CDJ92557.1 - 7.2e-12 45.6 0.1 1.9e-11 44.3 0.1 1.7 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal Hydrolase PF00702.26 CDJ92557.1 - 8.7e-12 45.8 0.1 1.8e-11 44.7 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDJ92557.1 - 1.9e-07 31.1 1.2 3.4e-05 23.7 0.7 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase ATG22 PF11700.8 CDJ92557.1 - 0.0018 17.0 0.1 0.0041 15.8 0.1 1.5 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Nucleos_tra2_C PF07662.13 CDJ92557.1 - 7.1 6.4 7.0 2.3 8.0 0.6 2.8 2 1 0 2 2 2 0 Na+ dependent nucleoside transporter C-terminus ANF_receptor PF01094.28 CDJ92558.1 - 1.3e-48 165.9 1.2 2.1e-48 165.2 1.2 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 CDJ92558.1 - 2e-23 83.0 0.0 1.6e-22 80.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ92558.1 - 8.8e-21 74.4 0.0 2.4e-20 73.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Guanylate_cyc PF00211.20 CDJ92558.1 - 2.6e-12 46.7 0.1 1.1e-10 41.4 0.0 2.8 3 0 0 3 3 3 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 CDJ92558.1 - 0.0021 17.5 0.7 0.0038 16.7 0.7 1.4 1 0 0 1 1 1 1 Heme NO binding associated Peripla_BP_6 PF13458.6 CDJ92558.1 - 0.018 14.7 0.6 0.068 12.8 0.6 1.8 1 1 0 1 1 1 0 Periplasmic binding protein DUF745 PF05335.13 CDJ92558.1 - 0.091 12.5 0.2 0.23 11.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF4282 PF14110.6 CDJ92559.1 - 1.7 9.4 5.0 8.4 7.2 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) Macoilin PF09726.9 CDJ92559.1 - 3.2 6.2 7.9 4.1 5.9 7.9 1.1 1 0 0 1 1 1 0 Macoilin family DUF2569 PF10754.9 CDJ92559.1 - 5.9 7.3 7.4 0.43 11.0 2.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) E1-E2_ATPase PF00122.20 CDJ92560.1 - 2e-36 125.2 2.1 2e-36 125.2 2.1 1.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 CDJ92560.1 - 1.5e-15 57.0 0.0 4.1e-15 55.6 0.0 1.8 1 1 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CDJ92560.1 - 3.5e-13 50.3 0.0 5.7e-12 46.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CDJ92560.1 - 2.7e-10 39.8 0.0 8.2e-10 38.2 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Rer1 PF03248.13 CDJ92560.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Rer1 family DUF4131 PF13567.6 CDJ92560.1 - 0.016 14.9 0.2 0.016 14.9 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Peptidase_C1 PF00112.23 CDJ92562.1 - 6.8e-75 251.9 0.3 6.8e-75 251.9 0.3 2.1 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CDJ92562.1 - 1.6e-14 54.1 0.2 4.6e-14 52.6 0.2 1.9 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Cystatin PF00031.21 CDJ92562.1 - 2.5e-09 37.2 0.2 4.4e-09 36.5 0.2 1.4 1 0 0 1 1 1 1 Cystatin domain Peptidase_C1_2 PF03051.15 CDJ92562.1 - 4.9e-05 22.3 1.2 0.0066 15.3 0.1 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Cathelicidins PF00666.17 CDJ92562.1 - 0.012 15.9 0.6 0.03 14.6 0.6 1.6 1 0 0 1 1 1 0 Cathelicidin RVT_1 PF00078.27 CDJ92563.1 - 5.9e-22 78.3 0.0 8.7e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cystatin PF00031.21 CDJ92565.1 - 2.4e-09 37.4 0.2 3.4e-09 36.9 0.2 1.4 1 1 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 CDJ92565.1 - 1.8e-05 25.0 0.2 0.0029 17.9 0.1 2.2 1 1 0 2 2 2 2 Aspartic acid proteinase inhibitor SCVP PF17619.2 CDJ92566.1 - 1.3e-13 51.6 0.0 1.6e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Secreted clade V proteins SapB_1 PF05184.15 CDJ92566.1 - 0.15 12.1 0.1 2.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Saposin-like type B, region 1 SCVP PF17619.2 CDJ92567.1 - 1.6e-12 48.1 0.1 2e-12 47.8 0.1 1.1 1 0 0 1 1 1 1 Secreted clade V proteins Cystatin PF00031.21 CDJ92568.1 - 4.6e-08 33.2 0.1 2e-07 31.2 0.1 1.8 1 1 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 CDJ92568.1 - 0.0039 17.5 0.3 0.96 9.8 0.2 2.3 1 1 0 1 1 1 1 Aspartic acid proteinase inhibitor Exo_endo_phos_2 PF14529.6 CDJ92569.1 - 6.4e-05 22.8 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF3629 PF12302.8 CDJ92569.1 - 0.0077 15.7 1.2 0.0088 15.5 0.5 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3629) DivIC PF04977.15 CDJ92569.1 - 0.013 15.3 1.8 1.4 8.7 0.0 2.5 2 0 0 2 2 2 0 Septum formation initiator Lys PF00062.20 CDJ92570.1 - 0.028 14.7 0.1 0.048 13.9 0.1 1.3 1 0 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family BTB PF00651.31 CDJ92571.1 - 0.0044 17.2 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain DUF273 PF03314.14 CDJ92572.1 - 2.4e-37 128.6 2.2 4.8e-37 127.7 2.2 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF273 DUF273 PF03314.14 CDJ92573.1 - 4.7e-61 206.1 4.2 1.5e-38 132.6 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function, DUF273 Glyco_transf_34 PF05637.12 CDJ92573.1 - 0.00055 19.7 0.6 0.00089 19.0 0.6 1.3 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family GspL_C PF12693.7 CDJ92573.1 - 0.18 11.6 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 GspL periplasmic domain Ion_trans_2 PF07885.16 CDJ92574.1 - 2.9e-28 97.7 14.6 4e-16 58.7 3.0 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 CDJ92574.1 - 5.5e-06 25.8 11.3 1.4e-05 24.4 1.8 2.2 1 1 1 2 2 2 2 Ion transport protein Aldedh PF00171.22 CDJ92576.1 - 2.1e-82 277.1 0.0 2.5e-82 276.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BTB_2 PF02214.22 CDJ92577.1 - 8.7e-18 64.5 0.1 1.4e-17 63.9 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain Corona_nucleoca PF00937.18 CDJ92578.1 - 0.18 10.8 1.5 0.22 10.5 1.5 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein 3-HAO PF06052.12 CDJ92581.1 - 4.7e-25 88.0 0.0 8.2e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase RNase_H PF00075.24 CDJ92582.1 - 2.5e-14 53.7 0.0 1.1e-13 51.5 0.0 2.1 2 1 0 2 2 2 1 RNase H Met_10 PF02475.16 CDJ92583.1 - 1e-22 80.9 0.0 1.8e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 CDJ92583.1 - 0.00012 22.7 0.0 0.0015 19.2 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain RrnaAD PF00398.20 CDJ92583.1 - 0.0047 16.0 0.0 0.0082 15.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Cons_hypoth95 PF03602.15 CDJ92583.1 - 0.0085 15.8 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 CDJ92583.1 - 0.024 14.2 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_32 PF13679.6 CDJ92583.1 - 0.033 14.2 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 CDJ92583.1 - 0.058 12.3 0.0 0.093 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_15 PF09445.10 CDJ92583.1 - 0.089 12.4 0.1 0.92 9.1 0.0 2.0 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase DSL PF01414.19 CDJ92584.1 - 8.8e-12 45.1 1.8 8.8e-12 45.1 1.8 1.7 2 0 0 2 2 2 1 Delta serrate ligand Glyco_hydro_31 PF01055.26 CDJ92585.1 - 1.6e-141 472.5 1.5 2.3e-141 472.0 1.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CDJ92585.1 - 5.2e-21 74.7 0.2 1.9e-20 73.0 0.1 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 CDJ92585.1 - 0.0074 16.5 0.0 0.021 15.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) DUF4968 PF16338.5 CDJ92585.1 - 0.02 15.2 0.1 0.06 13.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4968) MFS_1 PF07690.16 CDJ92586.1 - 4.2e-11 42.4 23.9 4.2e-11 42.4 23.9 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.7 CDJ92587.1 - 2.7e-26 92.0 10.1 2.4e-09 37.7 0.2 5.2 2 1 4 6 6 6 4 Ankyrin repeats (3 copies) Notch PF00066.17 CDJ92587.1 - 8.4e-25 87.0 48.5 1.6e-12 47.7 8.0 5.8 7 0 0 7 7 4 3 LNR domain Ank_3 PF13606.6 CDJ92587.1 - 1.8e-21 73.9 6.1 0.00053 20.2 0.0 7.7 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 CDJ92587.1 - 1.1e-20 73.7 5.2 3.2e-07 30.8 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ92587.1 - 3.3e-19 68.7 11.1 7.1e-08 32.6 0.2 6.5 4 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 CDJ92587.1 - 4.6e-18 64.8 7.0 0.011 16.2 0.0 6.9 6 0 0 6 6 6 4 Ankyrin repeat EGF PF00008.27 CDJ92587.1 - 2.1e-12 47.1 37.4 3.2e-08 33.7 7.0 7.0 6 1 1 7 7 5 4 EGF-like domain NOD PF06816.13 CDJ92587.1 - 1e-11 44.3 0.1 2.9e-11 42.8 0.0 1.8 2 0 0 2 2 2 1 NOTCH protein EGF_CA PF07645.15 CDJ92587.1 - 7.3e-08 32.5 9.8 7.3e-08 32.5 9.8 6.9 5 2 1 6 6 5 2 Calcium-binding EGF domain hEGF PF12661.7 CDJ92587.1 - 2.6e-07 31.0 7.1 2.6e-07 31.0 7.1 8.6 8 1 1 9 9 9 3 Human growth factor-like EGF NODP PF07684.12 CDJ92587.1 - 2.6e-07 30.7 0.0 1.6e-06 28.2 0.0 2.4 1 0 0 1 1 1 1 NOTCH protein EGF_2 PF07974.13 CDJ92587.1 - 0.017 15.5 9.1 0.017 15.5 9.1 7.9 7 1 0 7 7 5 0 EGF-like domain SfsA_N PF17746.1 CDJ92587.1 - 0.15 12.3 0.0 0.53 10.5 0.0 1.9 1 0 0 1 1 1 0 SfsA N-terminal OB domain Orf78 PF06024.12 CDJ92588.1 - 0.16 12.3 0.0 0.23 11.8 0.0 1.2 1 0 0 1 1 1 0 Orf78 (ac78) Neur_chan_LBD PF02931.23 CDJ92589.1 - 7.8e-34 117.0 0.1 1e-33 116.6 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ92589.1 - 0.015 15.4 5.1 0.027 14.5 5.1 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region 7TM_GPCR_Srw PF10324.9 CDJ92590.1 - 1.2e-57 195.7 22.7 2.2e-57 194.7 22.7 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 CDJ92590.1 - 7.7e-10 38.5 22.9 2e-09 37.1 22.9 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) NMN_transporter PF04973.12 CDJ92591.1 - 0.15 12.0 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter GATA PF00320.27 CDJ92592.1 - 3.9e-18 64.7 16.2 1.9e-14 52.9 3.8 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 CDJ92592.1 - 0.003 17.0 3.1 0.037 13.5 0.5 2.4 2 0 0 2 2 2 1 TFIIB zinc-binding ArfGap PF01412.18 CDJ92592.1 - 0.02 15.0 3.4 0.037 14.1 3.4 1.5 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf DUF2387 PF09526.10 CDJ92592.1 - 0.12 12.5 3.3 18 5.5 0.0 3.3 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) Zn_Tnp_IS1595 PF12760.7 CDJ92592.1 - 0.15 12.1 3.0 0.3 11.1 0.7 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Auto_anti-p27 PF06677.12 CDJ92592.1 - 0.27 11.4 4.2 1.7 8.9 0.6 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 CDJ92592.1 - 0.63 10.1 6.0 4.8 7.3 1.6 2.4 1 1 1 2 2 2 0 Double zinc ribbon Prim_Zn_Ribbon PF08273.12 CDJ92592.1 - 1.1 9.6 5.9 0.34 11.2 1.7 2.2 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase zf-ribbon_3 PF13248.6 CDJ92592.1 - 1.4 8.4 4.5 25 4.5 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Herpes_capsid PF06112.11 CDJ92592.1 - 2.1 8.4 10.3 3.5 7.7 10.3 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Rubredoxin_2 PF18073.1 CDJ92592.1 - 3.4 7.5 7.0 39 4.1 0.1 3.3 3 0 0 3 3 3 0 Rubredoxin metal binding domain Lectin_C PF00059.21 CDJ92594.1 - 1.3e-16 61.2 1.2 1.8e-16 60.8 1.2 1.1 1 0 0 1 1 1 1 Lectin C-type domain HECT PF00632.25 CDJ92595.1 - 1.1e-87 294.4 0.0 1.4e-87 294.1 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECW1_helix PF18436.1 CDJ92595.1 - 1.9e-24 85.6 0.1 3.9e-24 84.6 0.1 1.5 1 0 0 1 1 1 1 Helical box domain of E3 ubiquitin-protein ligase HECW1 ART PF01129.18 CDJ92595.1 - 0.018 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase Neur_chan_LBD PF02931.23 CDJ92596.1 - 2e-42 145.1 0.0 2.5e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ92596.1 - 1.3e-36 126.9 3.4 1.7e-36 126.5 3.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Rod_C PF10493.9 CDJ92598.1 - 9.8e-17 60.5 1.2 9.8e-17 60.5 1.2 1.7 2 0 0 2 2 2 1 Rough deal protein C-terminal region ANAPC4_WD40 PF12894.7 CDJ92598.1 - 0.034 14.5 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain MRC1 PF09444.10 CDJ92599.1 - 0.079 13.5 3.2 0.12 12.8 3.2 1.3 1 0 0 1 1 1 0 MRC1-like domain HSA PF07529.13 CDJ92599.1 - 0.44 10.9 6.0 2.4 8.5 2.3 2.7 2 1 0 2 2 2 0 HSA ApeC PF16977.5 CDJ92601.1 - 0.00014 21.9 0.0 0.00017 21.6 0.0 1.2 1 0 0 1 1 1 1 C-terminal domain of apextrin DUF3764 PF12594.8 CDJ92601.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3764) DTC PF18102.1 CDJ92602.1 - 3.4e-50 169.6 0.2 1.4e-49 167.6 0.1 1.9 2 0 0 2 2 2 1 Deltex C-terminal domain zf-RING_11 PF17123.5 CDJ92602.1 - 3.7e-06 26.6 4.2 1.1e-05 25.0 4.2 1.9 1 0 0 1 1 1 1 RING-like zinc finger Macro PF01661.21 CDJ92602.1 - 1.9e-05 24.7 0.0 3.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Macro domain zf-RING_2 PF13639.6 CDJ92602.1 - 2e-05 24.8 13.9 2e-05 24.8 13.9 2.0 2 0 0 2 2 2 1 Ring finger domain zf-ANAPC11 PF12861.7 CDJ92602.1 - 0.0025 17.8 2.3 0.0025 17.8 2.3 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CDJ92602.1 - 0.0068 16.2 10.8 0.015 15.2 10.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDJ92602.1 - 0.0069 16.7 9.2 0.017 15.4 9.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CDJ92602.1 - 0.049 13.6 13.6 0.1 12.6 13.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CDJ92602.1 - 0.12 12.3 10.7 0.26 11.2 10.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 CDJ92602.1 - 0.32 11.3 15.2 0.18 12.1 6.9 2.4 2 0 0 2 2 2 0 RING-like domain Rad50_zn_hook PF04423.14 CDJ92602.1 - 0.38 10.6 5.4 12 5.9 2.8 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif Astacin PF01400.24 CDJ92603.1 - 3.5e-49 167.0 0.0 6.7e-49 166.1 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 CDJ92603.1 - 0.0036 17.0 0.1 0.007 16.0 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CDJ92603.1 - 0.0043 16.9 0.0 0.0063 16.4 0.0 1.4 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 CDJ92603.1 - 0.026 13.5 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_5 PF13688.6 CDJ92603.1 - 0.055 13.6 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12 CUB PF00431.20 CDJ92603.1 - 0.082 13.2 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 CUB domain Flu_NS2 PF00601.19 CDJ92603.1 - 0.15 12.4 0.4 0.3 11.4 0.4 1.5 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) Reprolysin_3 PF13582.6 CDJ92603.1 - 0.15 12.6 2.9 0.14 12.7 1.0 2.1 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like RVT_1 PF00078.27 CDJ92605.1 - 7.4e-05 22.4 0.0 0.0001 21.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5037 PF16440.5 CDJ92605.1 - 0.076 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5037) Calponin PF00402.18 CDJ92608.1 - 1.4e-10 40.6 2.7 2.1e-10 40.0 2.7 1.3 1 0 0 1 1 1 1 Calponin family repeat CH PF00307.31 CDJ92608.1 - 3.3e-05 24.0 0.2 5.4e-05 23.3 0.1 1.4 2 0 0 2 2 2 1 Calponin homology (CH) domain Dec-1 PF04624.14 CDJ92608.1 - 0.078 12.8 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Dec-1 repeat zf-C2H2 PF00096.26 CDJ92609.1 - 3.2e-23 80.8 32.2 3.2e-05 24.1 0.6 5.6 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ92609.1 - 4.9e-19 67.4 34.0 0.001 19.7 0.3 6.2 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDJ92609.1 - 6.5e-16 57.9 31.1 6.5e-05 23.2 0.6 5.8 6 0 0 6 6 5 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 CDJ92609.1 - 7.2e-10 38.6 21.8 0.00022 21.1 0.9 5.6 4 1 1 5 5 5 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ92609.1 - 2.4e-07 30.9 14.9 0.025 14.9 0.1 5.0 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 CDJ92609.1 - 9.6e-07 28.5 31.4 0.066 13.0 0.2 5.4 4 1 1 5 5 5 4 zinc-finger C2H2-type zf-met PF12874.7 CDJ92609.1 - 0.00045 20.5 21.1 0.12 12.8 0.5 5.3 5 0 0 5 5 5 2 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 CDJ92609.1 - 0.00093 19.3 16.5 0.68 10.1 0.1 4.4 3 2 0 3 3 3 2 Zinc ribbon domain zf_UBZ PF18439.1 CDJ92609.1 - 0.0021 17.6 10.8 2.5 7.8 0.1 5.1 5 0 0 5 5 5 2 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 CDJ92609.1 - 0.0021 18.7 14.6 1.2 9.9 0.5 4.2 2 1 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats HypA PF01155.19 CDJ92609.1 - 0.018 15.0 12.5 0.9 9.6 2.4 3.3 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-NADH-PPase PF09297.11 CDJ92609.1 - 0.021 14.5 0.3 0.021 14.5 0.3 4.0 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_15 PF17032.5 CDJ92609.1 - 0.039 14.7 15.0 0.13 13.0 0.5 3.1 1 1 2 3 3 3 0 zinc-ribbon family Rpr2 PF04032.16 CDJ92609.1 - 0.043 14.1 13.6 2 8.8 0.3 3.0 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain ADK_lid PF05191.14 CDJ92609.1 - 0.049 13.6 16.7 0.53 10.3 1.1 4.0 3 1 1 4 4 4 0 Adenylate kinase, active site lid TerY_C PF15616.6 CDJ92609.1 - 0.052 13.7 6.6 1.4 9.0 0.1 2.5 1 1 1 2 2 2 0 TerY-C metal binding domain zf-C2HE PF16278.5 CDJ92609.1 - 0.071 13.6 21.5 2.2 8.8 0.1 5.3 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger DUF2256 PF10013.9 CDJ92609.1 - 0.088 12.9 14.0 10 6.3 0.1 5.0 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-BED PF02892.15 CDJ92609.1 - 0.11 12.6 0.3 0.11 12.6 0.3 5.4 3 2 2 5 5 4 0 BED zinc finger zf-AN1 PF01428.16 CDJ92609.1 - 0.13 12.4 17.1 7.6 6.8 0.1 5.3 5 0 0 5 5 5 0 AN1-like Zinc finger zf_C2H2_13 PF18508.1 CDJ92609.1 - 0.27 10.9 7.2 19 5.0 0.2 4.2 3 1 1 4 4 4 0 Zinc finger domain DUF3268 PF11672.8 CDJ92609.1 - 0.31 11.4 7.0 1.3 9.3 0.3 2.5 2 0 0 2 2 2 0 zinc-finger-containing domain zf-MYND PF01753.18 CDJ92609.1 - 0.61 10.2 16.7 1.3 9.1 1.4 3.6 2 1 1 3 3 3 0 MYND finger FYVE PF01363.21 CDJ92609.1 - 0.67 10.1 25.5 0.18 12.0 6.4 3.7 1 1 3 4 4 4 0 FYVE zinc finger HNH_5 PF14279.6 CDJ92609.1 - 1.2 9.1 9.8 0.5 10.3 0.4 3.6 3 1 0 3 3 3 0 HNH endonuclease zf_ZIC PF18366.1 CDJ92609.1 - 1.6 8.9 9.2 11 6.2 0.6 4.1 1 1 4 5 5 5 0 Zic proteins zinc finger domain zf-C2HC_2 PF13913.6 CDJ92609.1 - 2.2 8.3 29.0 0.16 11.9 1.7 6.0 6 0 0 6 6 6 0 zinc-finger of a C2HC-type Cript PF10235.9 CDJ92609.1 - 3.1 8.5 13.8 24 5.6 1.1 4.3 3 1 1 4 4 4 0 Microtubule-associated protein CRIPT zf-C2H2_9 PF16293.5 CDJ92609.1 - 5.5 6.9 8.4 6.9 6.6 0.8 3.3 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_4 PF13717.6 CDJ92609.1 - 9.4 6.3 20.1 35 4.4 0.4 5.2 4 1 1 5 5 5 0 zinc-ribbon domain Peptidase_S28 PF05577.12 CDJ92610.1 - 1.7e-52 178.7 4.1 4e-48 164.3 1.2 2.0 1 1 1 2 2 2 2 Serine carboxypeptidase S28 RRM_1 PF00076.22 CDJ92611.1 - 0.00013 21.8 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDJ92611.1 - 0.0003 20.7 0.0 0.00046 20.1 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 CDJ92611.1 - 0.14 12.1 0.0 0.78 9.7 0.0 2.3 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Pkinase PF00069.25 CDJ92612.1 - 3e-19 69.4 0.8 4.6e-19 68.8 0.8 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ92612.1 - 2.8e-08 33.4 0.4 4.2e-08 32.8 0.4 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ92612.1 - 0.0015 17.9 0.0 0.0044 16.4 0.0 1.7 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDJ92612.1 - 0.0078 15.0 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase DUF4551 PF15087.6 CDJ92613.1 - 9.9 4.9 12.7 11 4.8 12.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Laminin_G_2 PF02210.24 CDJ92617.1 - 7e-28 97.7 9.5 7.1e-11 42.8 0.0 5.5 5 1 0 5 5 5 4 Laminin G domain Laminin_G_1 PF00054.23 CDJ92617.1 - 2e-16 60.4 3.1 5.2e-09 36.4 0.1 6.0 6 1 0 6 6 6 3 Laminin G domain Laminin_G_3 PF13385.6 CDJ92617.1 - 0.017 15.3 0.3 0.099 12.8 0.0 2.4 3 0 0 3 3 3 0 Concanavalin A-like lectin/glucanases superfamily LRR19-TM PF15176.6 CDJ92617.1 - 0.04 13.9 0.0 0.096 12.7 0.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Collagen PF01391.18 CDJ92618.1 - 3.9e-22 77.8 110.6 1.8e+04 -36.1 110.6 4.1 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ92618.1 - 5.3e-11 42.4 0.2 7.5e-11 41.9 0.2 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ92619.1 - 2.9e-23 81.4 94.5 3.4e-10 39.5 29.0 3.9 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ92619.1 - 5.2e-08 32.8 0.3 7.5e-08 32.3 0.3 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ92620.1 - 2.3e-22 78.5 107.0 0.0075 16.0 57.0 4.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ92620.1 - 2.1e-10 40.5 0.1 2.9e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain PCI PF01399.27 CDJ92621.1 - 6.1e-22 78.1 2.0 6.1e-22 78.1 2.0 2.5 2 1 0 2 2 2 1 PCI domain TPR_2 PF07719.17 CDJ92621.1 - 0.025 14.7 5.0 1.6 9.0 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ92621.1 - 0.091 12.6 5.6 1.7 8.6 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ92621.1 - 0.092 13.0 14.2 1.8 9.0 0.1 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ92621.1 - 0.094 12.4 1.3 0.46 10.2 0.1 2.8 3 0 0 3 3 3 0 TPR repeat TPR_7 PF13176.6 CDJ92621.1 - 0.11 12.6 6.9 13 6.1 0.0 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat NuA4 PF09340.10 CDJ92622.1 - 3.3e-24 84.5 0.1 3.3e-24 84.5 0.1 1.4 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 PI3Ka PF00613.20 CDJ92623.1 - 1.1e-49 168.4 0.7 2.1e-49 167.5 0.7 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 CDJ92623.1 - 5.3e-45 154.2 0.6 6.5e-43 147.3 0.6 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 CDJ92623.1 - 5.9e-23 81.3 0.1 1.8e-22 79.8 0.0 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 CDJ92623.1 - 0.034 13.5 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) PDZ_6 PF17820.1 CDJ92624.1 - 1.4e-09 37.7 0.0 1.2e-06 28.2 0.1 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CDJ92624.1 - 3.3e-07 30.5 0.0 2.7e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 CDJ92624.1 - 4.1e-06 27.0 0.0 0.0014 18.9 0.1 2.4 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 CDJ92624.1 - 0.01 15.8 0.0 0.067 13.2 0.0 2.2 2 0 0 2 2 2 0 Tricorn protease PDZ domain PDZ_4 PF17816.1 CDJ92624.1 - 0.12 12.8 0.0 20 5.6 0.0 2.9 2 1 1 3 3 3 0 PDZ domain Collagen PF01391.18 CDJ92625.1 - 1.7e-23 82.1 91.4 3.4e-08 33.1 33.6 4.7 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ92625.1 - 2.2e-10 40.4 1.0 2.7e-10 40.1 1.0 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain RRM_1 PF00076.22 CDJ92626.1 - 1.5e-17 63.1 0.0 3.4e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ92626.1 - 2.7e-06 27.4 0.0 1.1e-05 25.4 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif DUF1314 PF07013.11 CDJ92626.1 - 0.015 15.2 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) Nup35_RRM PF05172.13 CDJ92626.1 - 0.098 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Noggin PF05806.12 CDJ92626.1 - 0.15 11.9 5.9 0.28 11.1 5.9 1.5 1 0 0 1 1 1 0 Noggin DUF4695 PF15766.5 CDJ92626.1 - 0.21 11.8 8.4 0.42 10.9 8.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) DUF3069 PF11269.8 CDJ92626.1 - 0.28 11.4 14.7 0.63 10.3 10.0 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF3069) GAGA_bind PF06217.12 CDJ92626.1 - 0.35 11.1 10.4 0.58 10.4 10.4 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family CDC45 PF02724.14 CDJ92626.1 - 0.39 9.0 12.4 0.5 8.6 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein NARP1 PF12569.8 CDJ92626.1 - 0.91 8.3 22.3 1.5 7.6 22.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AAA_11 PF13086.6 CDJ92626.1 - 1.8 8.3 10.4 2.9 7.6 10.4 1.3 1 0 0 1 1 1 0 AAA domain Cas_CT1975 PF09344.10 CDJ92626.1 - 2.6 7.4 10.3 3.9 6.8 10.3 1.2 1 0 0 1 1 1 0 CT1975-like protein DUF4407 PF14362.6 CDJ92626.1 - 5.1 6.4 7.5 7.2 5.9 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RRN3 PF05327.11 CDJ92626.1 - 7.4 5.0 10.6 9.1 4.7 10.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Paramyxo_ncap PF00973.19 CDJ92626.1 - 8.7 5.1 9.4 12 4.7 9.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PHD PF00628.29 CDJ92627.1 - 9.2e-23 79.9 70.9 3.8e-09 36.3 9.9 6.7 5 1 1 6 6 6 5 PHD-finger SET PF00856.28 CDJ92627.1 - 6.7e-18 65.6 0.0 3.9e-17 63.2 0.0 2.4 1 1 0 1 1 1 1 SET domain FYRC PF05965.14 CDJ92627.1 - 4.9e-17 61.9 0.0 1.2e-16 60.6 0.0 1.8 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 CDJ92627.1 - 1.9e-16 59.7 0.6 3.7e-16 58.7 0.1 1.9 2 0 0 2 2 2 1 F/Y-rich N-terminus zf-HC5HC2H PF13771.6 CDJ92627.1 - 2e-09 37.5 6.3 2e-09 37.5 6.3 6.2 3 1 3 6 6 6 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CDJ92627.1 - 9.1e-09 35.5 7.2 9.1e-09 35.5 7.2 5.7 3 2 3 6 6 6 1 PHD-zinc-finger like domain HMG_box_2 PF09011.10 CDJ92627.1 - 0.0051 17.4 0.5 0.014 16.0 0.5 1.7 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 CDJ92627.1 - 0.16 12.4 0.5 0.42 11.0 0.5 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box Pam16 PF03656.13 CDJ92628.1 - 3.7e-48 162.7 1.6 7e-48 161.8 1.6 1.4 1 0 0 1 1 1 1 Pam16 FtsJ PF01728.19 CDJ92628.1 - 6.2e-32 111.1 0.0 1e-31 110.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase COMM_domain PF07258.14 CDJ92628.1 - 1.2e-08 34.9 0.6 2.6e-08 33.9 0.6 1.6 1 0 0 1 1 1 1 COMM domain Methyltransf_23 PF13489.6 CDJ92628.1 - 0.035 13.9 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ92628.1 - 0.15 12.8 0.1 1.3 9.8 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain PSK_trans_fac PF07704.11 CDJ92628.1 - 1.2 9.9 10.7 4.8 8.0 0.3 3.0 3 0 0 3 3 3 0 Rv0623-like transcription factor FeS_assembly_P PF01883.19 CDJ92629.1 - 2.1e-13 50.2 0.0 4.3e-13 49.2 0.0 1.5 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein Pkinase PF00069.25 CDJ92635.1 - 2.9e-62 210.4 0.0 4.8e-62 209.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ92635.1 - 1.9e-34 119.1 0.0 2.6e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 CDJ92635.1 - 6.4e-11 42.6 0.4 2.2e-10 40.8 0.4 1.9 1 1 0 1 1 1 1 Regulator of G protein signaling domain Kinase-like PF14531.6 CDJ92635.1 - 1.3e-06 28.0 0.0 2.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CDJ92635.1 - 1.5e-05 23.9 0.0 2.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase LpqV PF17301.2 CDJ92635.1 - 0.17 12.1 0.6 0.38 11.0 0.6 1.5 1 1 0 1 1 1 0 Putative lipoprotein LpqV FTA2 PF13095.6 CDJ92635.1 - 0.18 11.4 2.4 8.1 6.0 0.0 2.9 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 RT_RNaseH_2 PF17919.1 CDJ92636.1 - 2.8e-30 104.3 0.0 5.1e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ92636.1 - 3.1e-30 104.6 0.0 5.1e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase fn3 PF00041.21 CDJ92639.1 - 4.2e-55 184.1 11.7 3.8e-14 52.8 0.3 4.9 4 1 0 4 4 4 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CDJ92639.1 - 4.1e-22 78.6 7.5 3.8e-07 30.6 0.4 4.5 4 0 0 4 4 4 4 Purple acid Phosphatase, N-terminal domain Ig_3 PF13927.6 CDJ92639.1 - 1.1e-07 32.4 1.0 8e-07 29.6 0.0 3.0 4 0 0 4 4 4 1 Immunoglobulin domain Interfer-bind PF09294.10 CDJ92639.1 - 2.2e-06 27.9 0.2 2.2 8.6 0.0 4.7 5 0 0 5 5 5 2 Interferon-alpha/beta receptor, fibronectin type III I-set PF07679.16 CDJ92639.1 - 2.6e-06 27.4 0.0 2.7e-05 24.1 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin I-set domain fn3_4 PF16794.5 CDJ92639.1 - 4.5e-05 23.3 0.2 2.4 8.1 0.0 4.0 3 0 0 3 3 3 2 Fibronectin-III type domain fn3_2 PF16893.5 CDJ92639.1 - 0.0001 22.4 0.1 0.16 12.1 0.0 3.4 3 0 0 3 3 3 1 Fibronectin type III domain ig PF00047.25 CDJ92639.1 - 0.0007 19.7 0.0 0.0027 17.8 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain DUF2369 PF10179.9 CDJ92639.1 - 0.0011 19.3 0.0 0.25 11.7 0.0 2.8 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2369) Ig_2 PF13895.6 CDJ92639.1 - 0.0014 18.9 0.0 0.0049 17.2 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin domain Arylsulfotran_N PF17425.2 CDJ92639.1 - 0.015 15.3 0.2 32 4.7 0.0 3.6 3 0 0 3 3 3 0 Arylsulfotransferase Ig-like domain DUF4945 PF16303.5 CDJ92639.1 - 0.039 13.9 0.1 0.46 10.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4945) 7tm_1 PF00001.21 CDJ92641.1 - 1.5e-16 60.5 20.2 1.7e-16 60.3 20.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Collagen PF01391.18 CDJ92642.1 - 1.9e-25 88.4 110.3 2.2e-09 36.9 36.4 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ92642.1 - 0.00056 19.9 0.0 0.00082 19.4 0.0 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Arm_2 PF04826.13 CDJ92643.1 - 7.6e-07 28.8 0.0 1.6e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 Armadillo-like HlyIII PF03006.20 CDJ92644.1 - 1e-40 139.9 23.7 1.2e-40 139.6 23.7 1.0 1 0 0 1 1 1 1 Haemolysin-III related TIMP PF00965.17 CDJ92645.1 - 2.1e-19 70.0 0.0 2.6e-19 69.8 0.0 1.0 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.21 CDJ92645.1 - 0.00026 20.7 0.0 0.00039 20.2 0.0 1.3 1 0 0 1 1 1 1 UNC-6/NTR/C345C module AMP-binding PF00501.28 CDJ92646.1 - 4.6e-59 200.1 0.0 5.2e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme 7TM_GPCR_Srd PF10317.9 CDJ92647.1 - 3.6e-51 174.1 20.3 4.5e-51 173.8 20.3 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Str PF10326.9 CDJ92647.1 - 1e-10 41.5 19.6 1.4e-10 41.1 19.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srh PF10318.9 CDJ92647.1 - 2.1e-10 40.1 20.0 2.9e-10 39.7 20.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Srj PF10319.9 CDJ92647.1 - 4.8e-07 29.4 19.4 2.2e-06 27.3 19.4 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Sri PF10327.9 CDJ92647.1 - 2.3e-06 27.0 20.0 1.4e-05 24.5 20.0 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri DUF3303 PF11746.8 CDJ92647.1 - 0.15 12.4 0.0 1 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3303) RVT_1 PF00078.27 CDJ92648.1 - 1.6e-46 158.6 0.0 2.5e-46 158.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7TM_GPCR_Srd PF10317.9 CDJ92649.1 - 3.3e-32 111.8 15.4 4e-32 111.6 15.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Str PF10326.9 CDJ92649.1 - 1.7e-07 30.9 14.3 2.3e-07 30.5 14.3 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srd PF10317.9 CDJ92650.1 - 2.7e-66 223.8 20.5 3.1e-66 223.6 20.5 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Str PF10326.9 CDJ92650.1 - 2.9e-16 59.7 19.3 4.9e-16 59.0 19.3 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srh PF10318.9 CDJ92650.1 - 6.6e-14 51.6 20.5 9.3e-14 51.1 20.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Srj PF10319.9 CDJ92650.1 - 6.9e-10 38.8 21.0 7.9e-09 35.3 21.0 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Sri PF10327.9 CDJ92650.1 - 3.9e-08 32.9 16.3 4.8e-08 32.5 16.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri C2 PF00168.30 CDJ92651.1 - 1.1e-43 147.7 0.0 4.5e-22 78.3 0.0 2.3 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 CDJ92651.1 - 0.019 14.9 0.0 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 CEP76-C2 PF15627.6 CDJ92651.1 - 0.16 11.5 0.0 1.9 8.1 0.0 2.2 2 0 0 2 2 2 0 CEP76 C2 domain DUF2285 PF10074.9 CDJ92652.1 - 0.0038 17.8 0.4 0.18 12.4 0.0 3.0 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2285) Lyase_1 PF00206.20 CDJ92654.1 - 2.6e-123 411.4 0.0 3.4e-123 411.0 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 CDJ92654.1 - 1.7e-26 92.4 0.1 4.2e-26 91.1 0.1 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_N PF08240.12 CDJ92654.1 - 0.07 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Ig_3 PF13927.6 CDJ92655.1 - 1.6e-05 25.4 0.0 3.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain UL45 PF05473.12 CDJ92655.1 - 0.00096 18.8 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like I-set PF07679.16 CDJ92655.1 - 0.0016 18.5 0.0 0.0029 17.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 CDJ92655.1 - 0.0096 16.2 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 CDJ92655.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain SBP56 PF05694.11 CDJ92656.1 - 1.4e-174 581.3 0.0 1.7e-174 580.9 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Transposase_1 PF01359.18 CDJ92656.1 - 5.4e-12 45.4 0.6 1.2e-11 44.3 0.6 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) Lactonase PF10282.9 CDJ92656.1 - 0.0023 17.2 0.0 0.011 15.0 0.0 2.1 3 0 0 3 3 3 1 Lactonase, 7-bladed beta-propeller GerE PF00196.19 CDJ92656.1 - 0.011 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 CDJ92656.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 DUF5090 PF17009.5 CDJ92657.1 - 0.031 14.3 1.6 0.069 13.1 1.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) Neur_chan_memb PF02932.16 CDJ92657.1 - 2.2 8.3 10.1 3 7.9 10.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NNMT_PNMT_TEMT PF01234.17 CDJ92658.1 - 1.3e-81 273.6 0.0 1.5e-81 273.4 0.0 1.0 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_23 PF13489.6 CDJ92658.1 - 6.7e-06 26.0 0.0 9.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.16 CDJ92658.1 - 1e-05 24.8 0.0 1.5e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme NodS PF05401.11 CDJ92658.1 - 0.0021 17.7 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_25 PF13649.6 CDJ92658.1 - 0.0099 16.6 0.0 0.24 12.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ92658.1 - 0.014 16.1 0.0 0.11 13.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.13 CDJ92658.1 - 0.22 10.9 0.0 12 5.1 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Pkinase PF00069.25 CDJ92659.1 - 4.6e-15 55.7 0.0 5.5e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ92659.1 - 1.4e-09 37.6 0.0 2.8e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ92659.1 - 0.004 17.1 0.0 3.6 7.5 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ92659.1 - 0.012 14.4 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Metal_resist PF13801.6 CDJ92660.1 - 1.9e-06 28.1 1.9 0.0062 16.7 0.0 3.7 4 0 0 4 4 4 1 Heavy-metal resistance DUF148 PF02520.17 CDJ92660.1 - 2.8e-05 24.2 7.0 2.8e-05 24.2 7.0 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF148 KMP11 PF03037.16 CDJ92660.1 - 0.018 15.8 6.6 0.019 15.7 1.4 2.3 1 1 1 2 2 2 0 Kinetoplastid membrane protein 11 Mer2 PF09074.10 CDJ92660.1 - 0.1 12.4 4.2 0.31 10.8 4.2 1.7 1 1 0 1 1 1 0 Mer2 HEPN-like_int PF18867.1 CDJ92660.1 - 0.16 11.8 1.9 0.31 10.9 1.5 1.7 1 1 0 1 1 1 0 HEPN-like integron domain ING PF12998.7 CDJ92660.1 - 0.18 12.4 4.2 11 6.7 4.2 2.4 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding APG6_N PF17675.1 CDJ92660.1 - 0.41 11.2 6.7 0.62 10.6 6.1 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region LMBR1 PF04791.16 CDJ92660.1 - 1 8.2 2.7 1.6 7.5 2.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein HMG_box_2 PF09011.10 CDJ92660.1 - 1.5 9.5 4.8 0.48 11.1 0.7 2.2 2 1 0 2 2 2 0 HMG-box domain Kelch_1 PF01344.25 CDJ92661.1 - 3.8e-67 221.7 19.8 2.4e-13 49.5 0.1 6.6 6 1 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CDJ92661.1 - 1e-40 136.7 3.2 4.2e-08 33.2 0.0 6.3 3 2 3 6 6 6 6 Kelch motif BACK PF07707.15 CDJ92661.1 - 1.4e-33 115.1 1.0 1.4e-33 115.1 1.0 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 CDJ92661.1 - 5.5e-29 100.6 0.1 8.8e-29 100.0 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 CDJ92661.1 - 7.7e-21 73.8 8.7 6.2e-05 22.9 0.0 6.5 4 3 2 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 CDJ92661.1 - 8.8e-21 73.0 14.3 7.5e-05 22.6 0.1 6.9 6 1 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 CDJ92661.1 - 1e-15 57.5 6.2 0.014 15.7 0.1 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ92661.1 - 1.6e-05 24.8 9.0 9.7 6.3 0.0 6.2 6 0 0 6 6 6 2 Kelch motif PQQ_3 PF13570.6 CDJ92661.1 - 4.2 8.0 13.8 5.1 7.7 0.0 5.3 6 0 0 6 6 6 0 PQQ-like domain Thyroglobulin_1 PF00086.18 CDJ92662.1 - 8.8e-17 60.5 15.8 4.4e-13 48.7 1.2 3.1 3 0 0 3 3 3 2 Thyroglobulin type-1 repeat Kunitz_BPTI PF00014.23 CDJ92662.1 - 1.1e-11 44.7 9.0 1.1e-11 44.7 9.0 2.3 2 0 0 2 2 2 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Lustrin_cystein PF14625.6 CDJ92662.1 - 0.029 14.7 5.6 0.029 14.7 5.6 5.2 6 0 0 6 6 6 0 Lustrin, cysteine-rich repeated domain Thyroglobulin_1 PF00086.18 CDJ92663.1 - 5.2e-16 58.1 17.6 1.8e-11 43.6 1.0 3.3 3 0 0 3 3 3 2 Thyroglobulin type-1 repeat Kunitz_BPTI PF00014.23 CDJ92663.1 - 1.7e-11 44.2 6.3 1.7e-11 44.2 6.3 2.2 2 0 0 2 2 2 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Lustrin_cystein PF14625.6 CDJ92663.1 - 0.032 14.6 4.1 0.032 14.6 4.1 4.5 5 2 0 5 5 5 0 Lustrin, cysteine-rich repeated domain Pyridoxal_deC PF00282.19 CDJ92664.1 - 1.5e-20 73.3 0.0 2.9e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 CDJ92664.1 - 0.0022 17.4 0.1 0.0034 16.7 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CDJ92664.1 - 0.0024 16.9 0.0 0.0043 16.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V 7TM_GPCR_Srd PF10317.9 CDJ92668.1 - 4.3e-55 187.0 31.9 5.3e-55 186.7 31.9 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Str PF10326.9 CDJ92668.1 - 5e-12 45.8 29.2 2.6e-10 40.1 29.2 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srj PF10319.9 CDJ92668.1 - 1.1e-06 28.2 22.2 2.2e-05 24.0 22.2 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj PP2C_C PF07830.13 CDJ92669.1 - 0.0033 17.9 0.2 0.0067 16.9 0.2 1.4 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain Kelch_1 PF01344.25 CDJ92670.1 - 5e-34 115.6 18.2 1.1e-09 37.7 0.1 5.9 6 1 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 CDJ92670.1 - 3.1e-26 90.7 6.0 1.8e-05 24.9 0.0 5.5 3 1 2 5 5 5 4 Kelch motif Kelch_2 PF07646.15 CDJ92670.1 - 2.5e-11 43.1 12.4 0.0061 16.5 0.0 5.2 4 2 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 CDJ92670.1 - 6e-11 42.2 4.9 0.025 14.6 0.0 4.6 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ92670.1 - 5e-08 33.0 9.6 0.023 15.0 0.0 5.3 4 3 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ92670.1 - 2.2e-06 27.5 7.5 0.46 10.5 0.2 4.4 4 0 0 4 4 4 3 Kelch motif PQQ_3 PF13570.6 CDJ92670.1 - 0.067 13.7 4.9 2.9 8.5 0.0 4.0 4 0 0 4 4 4 0 PQQ-like domain zf-RING_5 PF14634.6 CDJ92671.1 - 1e-10 41.4 9.8 2.3e-10 40.3 9.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDJ92671.1 - 2.7e-06 27.1 5.3 6.7e-06 25.9 5.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CDJ92671.1 - 5.7e-05 22.9 6.4 0.00013 21.8 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CDJ92671.1 - 0.027 14.6 6.7 0.027 14.6 6.7 1.8 2 0 0 2 2 1 0 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 CDJ92671.1 - 0.031 14.3 3.7 0.046 13.8 1.7 2.4 1 1 1 2 2 2 0 RING-type zinc-finger Exonuc_VII_L PF02601.15 CDJ92671.1 - 0.055 13.0 3.0 0.083 12.4 3.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-C3HC4 PF00097.25 CDJ92671.1 - 0.059 13.3 8.5 0.15 12.0 8.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RBP_receptor PF14752.6 CDJ92671.1 - 0.096 11.2 0.1 0.12 10.9 0.1 1.1 1 0 0 1 1 1 0 Retinol binding protein receptor zf-RING_2 PF13639.6 CDJ92671.1 - 0.21 11.9 7.4 0.43 11.0 7.4 1.5 1 0 0 1 1 1 0 Ring finger domain FapA PF03961.13 CDJ92671.1 - 1.1 7.8 5.3 1.5 7.4 5.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Uso1_p115_C PF04871.13 CDJ92671.1 - 1.5 9.2 9.1 2.8 8.3 9.1 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region zf-C3HC4_5 PF17121.5 CDJ92671.1 - 2.6 8.0 5.6 22 5.0 5.0 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ92671.1 - 3.8 7.4 11.0 24 4.9 10.3 2.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4407 PF14362.6 CDJ92671.1 - 8 5.7 7.4 11 5.2 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_C1 PF00112.23 CDJ92673.1 - 1.4e-66 224.7 3.8 1.8e-66 224.4 3.8 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ92673.1 - 0.016 14.0 2.2 0.022 13.5 0.2 1.9 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ92674.1 - 4.7e-66 223.0 6.9 5.7e-66 222.7 6.9 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ92674.1 - 0.11 11.3 4.5 0.076 11.8 0.8 2.0 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ92675.1 - 4.3e-60 203.5 7.8 5.4e-60 203.2 7.8 1.1 1 0 0 1 1 1 1 Papain family cysteine protease SPRR2 PF14820.6 CDJ92675.1 - 0.043 13.9 6.6 2.2 8.4 1.2 2.3 2 0 0 2 2 2 0 Small proline-rich 2 Peptidase_C1_2 PF03051.15 CDJ92675.1 - 0.076 11.8 0.9 0.12 11.1 0.6 1.4 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ92676.1 - 9.3e-64 215.5 6.3 1.2e-63 215.1 6.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ92676.1 - 0.00065 18.6 1.5 0.0027 16.5 0.6 2.0 2 0 0 2 2 2 1 Peptidase C1-like family RE_SinI PF09570.10 CDJ92677.1 - 0.062 12.5 0.0 0.064 12.5 0.0 1.1 1 0 0 1 1 1 0 SinI restriction endonuclease Cytochrome-c551 PF10643.9 CDJ92677.1 - 1.7 8.2 3.8 2.9 7.4 0.8 1.9 1 1 1 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 Cytochrome-c551 PF10643.9 CDJ92678.1 - 0.63 9.6 2.8 1.6 8.2 2.4 1.8 1 1 1 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 DUF4522 PF15022.6 CDJ92679.1 - 0.11 12.8 0.7 0.17 12.1 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) SNF PF00209.18 CDJ92681.1 - 1.9e-180 601.1 21.6 2.1e-180 600.9 21.6 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 CDJ92682.1 - 3.2e-10 39.3 7.8 3.8e-10 39.1 7.8 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Rft-1 PF04506.13 CDJ92682.1 - 0.0082 14.9 1.3 0.0097 14.7 1.3 1.0 1 0 0 1 1 1 1 Rft protein Arf PF00025.21 CDJ92683.1 - 5.7e-36 123.6 0.0 7.1e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CDJ92683.1 - 3e-14 52.9 0.0 3.9e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ92683.1 - 2.5e-13 50.3 0.1 3.3e-13 49.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CDJ92683.1 - 1e-10 41.4 0.0 1.2e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CDJ92683.1 - 2.3e-10 40.2 0.1 1.5e-07 30.9 0.0 2.6 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CDJ92683.1 - 8.2e-08 31.9 0.0 9.8e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDJ92683.1 - 1.9e-07 31.1 0.1 2.9e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ92683.1 - 0.002 17.7 0.1 0.013 15.1 0.0 2.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 CDJ92683.1 - 0.18 11.8 0.0 0.5 10.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain PDEase_I PF00233.19 CDJ92685.1 - 7.3e-28 97.9 0.1 8.9e-28 97.6 0.1 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Mtc PF03820.17 CDJ92686.1 - 1.6e-131 438.0 0.3 1.8e-131 437.8 0.3 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier CAP PF00188.26 CDJ92687.1 - 0.00069 20.5 0.0 0.0023 18.7 0.0 1.8 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Cation_efflux PF01545.21 CDJ92688.1 - 1.8e-24 86.6 9.1 2.2e-24 86.3 9.1 1.0 1 0 0 1 1 1 1 Cation efflux family RVT_1 PF00078.27 CDJ92689.1 - 9.9e-06 25.2 0.0 2.2e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YuiB PF14068.6 CDJ92691.1 - 0.058 14.0 0.1 0.079 13.6 0.1 1.1 1 0 0 1 1 1 0 Putative membrane protein Otopetrin PF03189.13 CDJ92692.1 - 3.7e-24 85.3 11.0 6.2e-22 78.0 11.0 2.3 1 1 0 1 1 1 1 Otopetrin Fasciclin PF02469.22 CDJ92694.1 - 4.9e-42 143.2 0.0 3.1e-20 72.7 0.0 5.1 4 1 0 4 4 4 4 Fasciclin domain COX7C PF02935.16 CDJ92695.1 - 1.1e-14 54.4 1.1 2e-14 53.6 1.1 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Innexin PF00876.18 CDJ92696.1 - 1.6e-64 218.4 7.1 1.9e-64 218.2 7.1 1.1 1 0 0 1 1 1 1 Innexin WAP PF00095.21 CDJ92697.1 - 1.2e-06 28.8 20.7 3.2e-05 24.2 10.0 2.1 2 0 0 2 2 2 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' Integrin_alpha2 PF08441.12 CDJ92698.1 - 2.1e-80 270.9 0.0 2.6e-80 270.6 0.0 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 CDJ92698.1 - 4.1e-19 68.4 24.2 4.1e-10 39.6 6.0 4.2 3 0 0 3 3 3 3 FG-GAP repeat VCBS PF13517.6 CDJ92698.1 - 7.3e-08 32.9 4.6 0.0067 17.0 0.2 3.2 1 1 2 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella LYRIC PF15686.5 CDJ92698.1 - 0.033 13.8 0.2 0.059 12.9 0.2 1.3 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Integrin_alpha PF00357.20 CDJ92698.1 - 0.57 10.3 3.6 1.8 8.8 3.6 1.9 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region FG-GAP_2 PF14312.6 CDJ92698.1 - 9.9 6.5 25.8 7.1 7.0 0.7 5.8 6 0 0 6 6 6 0 FG-GAP repeat BBL5 PF07289.11 CDJ92699.1 - 1.8e-15 56.8 0.0 2.5e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein RVT_1 PF00078.27 CDJ92701.1 - 1.4e-42 145.7 0.0 2.4e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDJ92701.1 - 3e-08 33.5 0.0 6.6e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase TAN PF11640.8 CDJ92701.1 - 0.051 13.7 0.3 0.15 12.2 0.3 1.7 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair REF PF05755.12 CDJ92701.1 - 0.052 13.4 0.2 0.092 12.6 0.2 1.3 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) CNOT1_TTP_bind PF16417.5 CDJ92701.1 - 0.13 11.4 0.1 0.35 10.0 0.1 1.7 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain YlmH_RBD PF17774.1 CDJ92701.1 - 0.14 12.5 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative RNA-binding domain in YlmH Claudin_2 PF13903.6 CDJ92704.1 - 0.0063 16.3 1.7 0.0063 16.3 1.7 1.9 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Sid-5 PF17204.3 CDJ92704.1 - 0.69 10.1 0.1 0.69 10.1 0.1 2.6 3 0 0 3 3 3 0 Sid-5 family Claudin_2 PF13903.6 CDJ92705.1 - 0.00078 19.2 2.1 0.00078 19.2 2.1 1.9 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Sid-5 PF17204.3 CDJ92705.1 - 0.25 11.5 9.8 0.34 11.1 0.1 2.7 2 1 1 3 3 3 0 Sid-5 family GlpM PF06942.12 CDJ92705.1 - 0.84 10.1 13.0 1.2 9.6 13.0 1.3 1 0 0 1 1 1 0 GlpM protein DHHC PF01529.20 CDJ92706.1 - 9.8 6.3 9.8 1.9 8.6 4.2 2.0 1 1 1 2 2 2 0 DHHC palmitoyltransferase WD40 PF00400.32 CDJ92707.1 - 4.1e-14 52.8 3.4 0.00074 20.3 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.8 CDJ92707.1 - 0.00014 20.6 4.5 0.0066 15.1 0.1 2.9 2 1 1 3 3 3 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CDJ92707.1 - 0.00017 21.8 0.3 1.7 9.0 0.0 3.7 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain FGGY_N PF00370.21 CDJ92708.1 - 5e-16 59.0 0.0 8.4e-09 35.3 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain RHD_dimer PF16179.5 CDJ92709.1 - 0.059 13.4 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Rel homology dimerisation domain Guanylate_kin PF00625.21 CDJ92711.1 - 6.8e-36 123.7 0.3 8.2e-36 123.4 0.3 1.1 1 0 0 1 1 1 1 Guanylate kinase ImpA_N PF06812.12 CDJ92711.1 - 0.053 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 ImpA, N-terminal, type VI secretion system Exo_endo_phos_2 PF14529.6 CDJ92712.1 - 0.0001 22.2 0.1 0.0003 20.6 0.1 1.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ92712.1 - 0.00028 20.5 0.1 0.00041 19.9 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 CDJ92713.1 - 3.9e-10 39.6 0.0 1.1e-09 38.1 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CDJ92714.1 - 8.7e-15 54.8 0.0 1.6e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Malic_M PF03949.15 CDJ92715.1 - 1.2e-82 277.1 0.3 2e-82 276.4 0.3 1.4 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CDJ92715.1 - 3.2e-71 238.9 0.0 5.3e-71 238.2 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 CDJ92716.1 - 7.3e-100 333.5 0.0 9.4e-100 333.1 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CDJ92716.1 - 1.8e-74 249.5 0.0 3.2e-74 248.6 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Patched PF02460.18 CDJ92717.1 - 1.4e-25 89.6 19.4 1.8e-25 89.3 19.4 1.0 1 0 0 1 1 1 1 Patched family TcdA_TcdB_pore PF12920.7 CDJ92717.1 - 5.5 5.1 4.7 8 4.6 4.7 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain Smg8_Smg9 PF10220.9 CDJ92718.1 - 1.9e-110 370.6 0.0 2.7e-110 370.2 0.0 1.0 1 0 0 1 1 1 1 Smg8_Smg9 Gp_dh_C PF02800.20 CDJ92718.1 - 5e-69 230.9 0.0 8.8e-69 230.1 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CDJ92718.1 - 7.8e-36 122.5 0.2 1.7e-35 121.4 0.2 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CDJ92718.1 - 0.051 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Oxidored_q5_N PF01059.17 CDJ92720.1 - 8.2e-06 25.9 6.7 8.2e-06 25.9 6.7 2.9 2 1 1 3 3 3 1 NADH-ubiquinone oxidoreductase chain 4, amino terminus MFS_1 PF07690.16 CDJ92721.1 - 2.9e-36 125.1 38.1 2.9e-36 125.1 38.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ92721.1 - 6.2e-13 48.4 11.6 6.2e-13 48.4 11.6 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.6 CDJ92721.1 - 0.00036 19.2 7.0 0.00036 19.2 7.0 2.9 2 1 1 3 3 3 2 MFS/sugar transport protein OATP PF03137.20 CDJ92721.1 - 0.009 14.3 24.6 0.065 11.5 0.7 4.0 3 1 1 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family EGF PF00008.27 CDJ92722.1 - 3.5e-14 52.8 50.4 5.3e-06 26.6 7.0 4.7 4 0 0 4 4 4 4 EGF-like domain Reeler PF02014.16 CDJ92722.1 - 3.3e-12 47.3 0.0 8.6e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Reeler domain hEGF PF12661.7 CDJ92722.1 - 9.1e-08 32.5 38.1 0.011 16.4 1.5 5.4 4 0 0 4 4 4 4 Human growth factor-like EGF ShK PF01549.24 CDJ92722.1 - 3.9e-07 30.5 4.5 3.9e-07 30.5 4.5 3.8 2 1 1 3 3 3 1 ShK domain-like DUF1794 PF08768.11 CDJ92722.1 - 7.7e-05 22.7 0.0 0.00018 21.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) EGF_2 PF07974.13 CDJ92722.1 - 0.0002 21.7 28.9 0.0024 18.2 10.6 5.0 5 0 0 5 5 5 3 EGF-like domain EGF_CA PF07645.15 CDJ92722.1 - 0.014 15.5 10.4 0.014 15.5 10.4 5.0 2 1 3 5 5 5 0 Calcium-binding EGF domain FXa_inhibition PF14670.6 CDJ92722.1 - 2 8.8 42.0 2.5 8.5 6.1 4.9 2 2 2 4 4 4 0 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 CDJ92722.1 - 2.8 8.2 62.5 0.15 12.3 5.0 4.8 4 0 0 4 4 4 0 EGF domain Beta-lactamase PF00144.24 CDJ92723.1 - 5.8e-40 137.5 0.0 7.3e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase PF00144.24 CDJ92724.1 - 2.3e-09 36.9 0.0 2.8e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase MFS_1 PF07690.16 CDJ92725.1 - 1.1e-34 119.9 29.6 1.5e-34 119.5 29.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ92725.1 - 3.5e-07 29.4 24.8 1.4e-05 24.2 4.9 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter Consortin_C PF15281.6 CDJ92725.1 - 0.042 13.9 0.1 0.084 12.9 0.1 1.4 1 0 0 1 1 1 0 Consortin C-terminus 7TM_GPCR_Srh PF10318.9 CDJ92726.1 - 1.3e-13 50.6 3.2 1.5e-13 50.5 3.2 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Sri PF10327.9 CDJ92726.1 - 2.3e-07 30.3 0.8 2.5e-07 30.2 0.8 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri 7TM_GPCR_Str PF10326.9 CDJ92726.1 - 0.0019 17.6 0.5 0.002 17.5 0.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str MFS_1 PF07690.16 CDJ92727.1 - 1.9e-07 30.3 3.3 2.7e-07 29.9 3.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 CDJ92728.1 - 3.4e-45 154.5 42.2 4.1e-37 127.9 29.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CDJ92728.1 - 1.8e-07 30.8 12.8 0.00074 18.9 0.1 3.3 2 1 1 3 3 3 3 Uncharacterised MFS-type transporter YbfB Ctr PF04145.15 CDJ92730.1 - 1.2e-27 97.4 1.9 1.4e-27 97.1 1.9 1.1 1 0 0 1 1 1 1 Ctr copper transporter family AzlD PF05437.12 CDJ92730.1 - 0.0095 16.1 1.9 0.0095 16.1 1.9 2.2 2 0 0 2 2 2 1 Branched-chain amino acid transport protein (AzlD) MTHFR PF02219.17 CDJ92731.1 - 8.5e-94 314.1 0.0 1.1e-93 313.8 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Asp PF00026.23 CDJ92732.1 - 7.6e-80 268.7 0.3 9.6e-80 268.3 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ92732.1 - 1.6e-09 38.3 9.4 2.8e-08 34.2 8.1 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ92732.1 - 8.8e-06 25.6 0.0 5.3e-05 23.0 0.0 2.3 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal MTHFR PF02219.17 CDJ92733.1 - 4.5e-05 22.9 0.0 0.00011 21.7 0.0 1.6 2 0 0 2 2 2 1 Methylenetetrahydrofolate reductase 7tm_2 PF00002.24 CDJ92734.1 - 3.5e-48 164.0 14.0 5.3e-48 163.5 14.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Gal_Lectin PF02140.18 CDJ92734.1 - 4.2e-21 75.2 0.3 1.4e-20 73.5 0.3 1.9 1 0 0 1 1 1 1 Galactose binding lectin domain GAIN PF16489.5 CDJ92734.1 - 9.1e-14 51.4 0.3 1.5e-13 50.7 0.3 1.3 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain GPS PF01825.21 CDJ92734.1 - 3.6e-12 46.6 9.9 3.6e-12 46.6 9.9 2.8 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif HRM PF02793.22 CDJ92734.1 - 3.7e-09 36.7 4.2 3.7e-09 36.7 4.2 2.2 2 0 0 2 2 2 1 Hormone receptor domain Dicty_CAR PF05462.11 CDJ92734.1 - 0.15 11.2 6.1 0.26 10.4 6.1 1.3 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor PRIMA1 PF16101.5 CDJ92734.1 - 2.9 8.0 6.8 68 3.5 4.7 2.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DEAD PF00270.29 CDJ92735.1 - 6.6e-28 97.7 0.1 1.1e-27 97.0 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ92735.1 - 2e-26 92.5 0.0 5.4e-26 91.1 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 CDJ92735.1 - 0.00017 22.0 0.0 0.092 13.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 CDJ92735.1 - 0.00081 19.4 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Hint PF01079.20 CDJ92737.1 - 2.5e-42 144.8 0.1 3.5e-42 144.3 0.1 1.2 1 0 0 1 1 1 1 Hint module Hint_2 PF13403.6 CDJ92737.1 - 0.081 13.2 0.1 0.31 11.3 0.0 1.9 2 0 0 2 2 2 0 Hint domain RNHCP PF12647.7 CDJ92737.1 - 1.4 8.9 3.8 2.6 8.1 3.8 1.4 1 0 0 1 1 1 0 RNHCP domain Rhabdo_M2 PF04785.12 CDJ92738.1 - 0.025 13.9 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus matrix protein M2 Asp PF00026.23 CDJ92739.1 - 5.6e-20 72.0 0.9 3.7e-10 39.7 0.1 3.0 1 1 2 3 3 3 3 Eukaryotic aspartyl protease HTH_24 PF13412.6 CDJ92741.1 - 0.0078 15.8 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding zf-C2H2 PF00096.26 CDJ92742.1 - 0.05 14.1 0.8 0.05 14.1 0.8 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 CDJ92742.1 - 0.14 12.8 7.5 0.2 12.3 0.0 3.4 2 1 1 3 3 3 0 FOXP coiled-coil domain ARD PF03079.14 CDJ92743.1 - 1.3e-50 171.6 0.1 1.5e-50 171.4 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 CDJ92743.1 - 7.8e-06 25.5 0.0 1.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 CDJ92743.1 - 9.2e-05 22.4 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_6 PF12852.7 CDJ92743.1 - 0.0027 17.4 0.0 0.0041 16.8 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 CDJ92743.1 - 0.0056 16.3 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.12 CDJ92743.1 - 0.011 15.5 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Cupin_1 PF00190.22 CDJ92743.1 - 0.023 14.3 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Cupin DUF3364 PF11844.8 CDJ92744.1 - 0.13 12.6 0.2 0.23 11.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3364) TTR-52 PF01060.23 CDJ92747.1 - 4e-26 91.5 0.4 5.4e-26 91.1 0.4 1.2 1 0 0 1 1 1 1 Transthyretin-like family bMG3 PF11974.8 CDJ92747.1 - 0.014 15.4 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain DUF4198 PF10670.9 CDJ92747.1 - 0.021 15.2 0.1 0.033 14.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) Transthyretin PF00576.21 CDJ92747.1 - 0.025 15.2 0.0 0.035 14.8 0.0 1.2 1 0 0 1 1 1 0 HIUase/Transthyretin family CarboxypepD_reg PF13620.6 CDJ92747.1 - 0.055 13.7 0.0 0.09 13.1 0.0 1.3 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain TTR-52 PF01060.23 CDJ92748.1 - 1.6e-25 89.6 0.3 2.1e-25 89.2 0.3 1.2 1 0 0 1 1 1 1 Transthyretin-like family Transthyretin PF00576.21 CDJ92748.1 - 0.014 16.1 0.0 0.017 15.8 0.0 1.2 1 0 0 1 1 1 0 HIUase/Transthyretin family bMG3 PF11974.8 CDJ92748.1 - 0.038 14.0 0.0 0.051 13.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain DUF4198 PF10670.9 CDJ92748.1 - 0.065 13.6 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) Peptidase_C53 PF05550.11 CDJ92748.1 - 0.079 12.6 0.0 0.092 12.4 0.0 1.1 1 0 0 1 1 1 0 Pestivirus Npro endopeptidase C53 CarboxypepD_reg PF13620.6 CDJ92748.1 - 0.092 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain TTR-52 PF01060.23 CDJ92749.1 - 1.4e-25 89.7 0.1 1.9e-25 89.4 0.1 1.1 1 0 0 1 1 1 1 Transthyretin-like family CarboxypepD_reg PF13620.6 CDJ92749.1 - 0.0049 17.1 0.0 0.0073 16.6 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain bMG3 PF11974.8 CDJ92749.1 - 0.0053 16.8 0.0 0.0073 16.3 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-2-macroglobulin MG3 domain Transthyretin PF00576.21 CDJ92749.1 - 0.0083 16.8 0.0 0.011 16.4 0.0 1.2 1 0 0 1 1 1 1 HIUase/Transthyretin family DUF1416 PF07210.12 CDJ92749.1 - 0.035 14.0 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) DUF4198 PF10670.9 CDJ92749.1 - 0.054 13.9 0.0 0.079 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) DUF916 PF06030.12 CDJ92749.1 - 0.11 12.6 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) TTR-52 PF01060.23 CDJ92750.1 - 4.8e-25 88.1 0.1 6.4e-25 87.7 0.1 1.2 1 0 0 1 1 1 1 Transthyretin-like family bMG3 PF11974.8 CDJ92750.1 - 0.099 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain TTR-52 PF01060.23 CDJ92751.1 - 7.7e-24 84.2 0.1 1.1e-23 83.8 0.1 1.2 1 0 0 1 1 1 1 Transthyretin-like family bMG3 PF11974.8 CDJ92751.1 - 0.035 14.1 0.0 0.048 13.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain Transthyretin PF00576.21 CDJ92751.1 - 0.1 13.3 0.0 0.21 12.3 0.0 1.4 1 1 0 1 1 1 0 HIUase/Transthyretin family Ras PF00071.22 CDJ92752.1 - 6.2e-18 64.9 0.3 7.9e-18 64.6 0.3 1.1 1 0 0 1 1 1 1 Ras family Synaptobrevin PF00957.21 CDJ92753.1 - 3e-26 91.0 5.7 3e-26 91.0 5.7 1.5 1 1 0 1 1 1 1 Synaptobrevin SGIII PF15467.6 CDJ92753.1 - 0.00044 19.6 0.2 0.00053 19.4 0.2 1.0 1 0 0 1 1 1 1 Secretogranin-3 EVI2A PF05399.11 CDJ92753.1 - 0.0063 16.1 0.1 0.0078 15.8 0.1 1.1 1 0 0 1 1 1 1 Ectropic viral integration site 2A protein (EVI2A) RIFIN PF02009.16 CDJ92753.1 - 0.0072 16.3 0.4 0.0086 16.0 0.4 1.0 1 0 0 1 1 1 1 Rifin Spc7 PF08317.11 CDJ92753.1 - 0.0084 15.0 1.3 0.01 14.8 1.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Sec5 PF15469.6 CDJ92753.1 - 0.01 15.7 0.8 0.015 15.1 0.8 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec5 KASH_CCD PF14662.6 CDJ92753.1 - 0.01 15.7 1.6 0.012 15.5 1.6 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF5345 PF17280.2 CDJ92753.1 - 0.077 13.0 0.1 0.077 13.0 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5345) m04gp34like PF12216.8 CDJ92753.1 - 0.11 12.1 0.6 0.15 11.6 0.4 1.3 1 1 0 1 1 1 0 Immune evasion protein HSBP1 PF06825.12 CDJ92753.1 - 1.3 9.0 6.1 8.1 6.4 0.2 2.6 1 1 1 2 2 2 0 Heat shock factor binding protein 1 TMEM156 PF15106.6 CDJ92753.1 - 1.9 7.8 6.7 2.5 7.5 6.5 1.4 1 1 0 1 1 1 0 TMEM156 protein family XhlA PF10779.9 CDJ92753.1 - 6.8 7.0 9.5 3.5 7.9 0.4 2.6 1 1 1 2 2 2 0 Haemolysin XhlA Lectin_C PF00059.21 CDJ92754.1 - 6.3e-12 46.2 0.1 6.3e-12 46.2 0.1 2.0 1 1 1 2 2 2 1 Lectin C-type domain Astacin PF01400.24 CDJ92755.1 - 0.00066 19.3 0.1 0.0013 18.4 0.1 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Cyclin PF08613.11 CDJ92756.1 - 1.3e-08 35.4 0.0 2e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CDJ92756.1 - 1.8e-05 24.5 0.0 3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Methyltransf_25 PF13649.6 CDJ92757.1 - 2.5e-05 24.9 0.0 4.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ92757.1 - 3.6e-05 23.6 0.0 7.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Spermine_synth PF01564.17 CDJ92757.1 - 0.00046 19.6 0.0 0.00086 18.8 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain RrnaAD PF00398.20 CDJ92757.1 - 0.0019 17.3 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_17 PF12692.7 CDJ92757.1 - 0.0025 17.8 0.0 0.005 16.8 0.0 1.5 1 1 0 1 1 1 1 S-adenosyl-L-methionine methyltransferase MTS PF05175.14 CDJ92757.1 - 0.005 16.4 0.0 0.0072 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 CDJ92757.1 - 0.0085 15.9 0.0 0.019 14.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MULE PF10551.9 CDJ92757.1 - 0.02 15.3 0.1 0.12 12.8 0.0 2.1 1 1 1 2 2 2 0 MULE transposase domain Cons_hypoth95 PF03602.15 CDJ92757.1 - 0.072 12.7 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 CDJ92757.1 - 0.13 13.0 0.0 0.22 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 CDJ92757.1 - 0.17 12.9 0.0 0.35 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain YcbB PF08664.10 CDJ92758.1 - 0.069 13.2 1.1 0.14 12.2 1.1 1.5 1 0 0 1 1 1 0 YcbB domain LTV PF04180.14 CDJ92759.1 - 4.2e-16 59.7 41.0 1.2e-09 38.4 22.5 3.6 1 1 2 3 3 3 2 Low temperature viability protein Peptidase_M14 PF00246.24 CDJ92760.1 - 1.2e-80 271.5 0.1 3.6e-80 269.9 0.1 1.9 3 0 0 3 3 3 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 CDJ92760.1 - 4.9e-10 39.5 0.0 2.6e-08 34.0 0.0 2.5 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF2012 PF09430.10 CDJ92760.1 - 0.00013 22.0 0.0 0.29 11.3 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF2012) AstE_AspA PF04952.14 CDJ92760.1 - 0.055 12.5 0.0 0.13 11.3 0.0 1.6 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Adeno_E3_CR2 PF02439.15 CDJ92760.1 - 1.2 8.9 3.2 2.7 7.8 3.2 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Spectrin PF00435.21 CDJ92761.1 - 0.0056 17.2 2.5 0.008 16.6 2.5 1.2 1 0 0 1 1 1 1 Spectrin repeat AAA_8 PF12780.7 CDJ92761.1 - 0.066 12.5 0.0 0.086 12.1 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Carb_anhydrase PF00194.21 CDJ92762.1 - 4.7e-48 164.0 0.0 6e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase C2 PF00168.30 CDJ92763.1 - 2.4e-38 130.5 0.1 8.4e-20 71.0 0.1 2.1 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 CDJ92763.1 - 0.014 15.0 0.0 0.52 9.9 0.0 2.3 2 0 0 2 2 2 0 CEP76 C2 domain RIG-I_C PF18119.1 CDJ92764.1 - 2.7e-20 72.8 2.2 2.7e-20 72.8 2.2 2.7 3 0 0 3 3 3 1 RIG-I receptor C-terminal domain RIG-I_C-RD PF11648.8 CDJ92764.1 - 5.1e-17 62.2 1.0 1.7e-16 60.5 1.0 1.9 1 0 0 1 1 1 1 C-terminal domain of RIG-I Helicase_C PF00271.31 CDJ92764.1 - 1.5e-16 60.7 0.3 5.2e-16 59.0 0.3 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2115 PF09888.9 CDJ92764.1 - 0.093 13.2 0.3 0.093 13.2 0.3 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) RrnaAD PF00398.20 CDJ92765.1 - 1.1e-36 126.3 0.0 1.3e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase tRNA-synt_2b PF00587.25 CDJ92766.1 - 4.5e-41 140.8 0.0 5.5e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF1966 PF09260.11 CDJ92766.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1966) DUF3719 PF12516.8 CDJ92767.1 - 9e-05 22.1 0.0 0.00017 21.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3719) DUF1325 PF07039.11 CDJ92771.1 - 1.7e-31 109.0 0.1 5.8e-31 107.3 0.0 1.8 2 0 0 2 2 2 1 SGF29 tudor-like domain TUDOR_5 PF18359.1 CDJ92771.1 - 0.04 13.6 0.0 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain 1 Tudor_3 PF18115.1 CDJ92771.1 - 0.083 12.7 0.6 0.23 11.3 0.1 2.0 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain ECSIT_C PF14784.6 CDJ92772.1 - 3.3e-26 92.2 0.1 3.9e-26 91.9 0.1 1.1 1 0 0 1 1 1 1 C-terminal domain of the ECSIT protein DUF3603 PF12227.8 CDJ92772.1 - 0.093 12.0 1.0 0.16 11.2 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3603) Hydrolase PF00702.26 CDJ92773.1 - 2.1e-11 44.5 0.0 1e-05 26.0 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDJ92773.1 - 0.00071 19.4 0.0 1.2 8.8 0.0 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase 2-Hacid_dh_C PF02826.19 CDJ92773.1 - 0.044 13.1 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DEAD PF00270.29 CDJ92774.1 - 1.8e-16 60.4 0.0 4.5e-16 59.1 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Ski2_N PF17911.1 CDJ92774.1 - 2.1e-15 56.7 0.1 4.1e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 Ski2 N-terminal region ResIII PF04851.15 CDJ92774.1 - 0.00034 20.7 0.0 0.00072 19.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DSHCT PF08148.12 CDJ92775.1 - 1.6e-38 132.0 0.0 4e-38 130.7 0.0 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 CDJ92775.1 - 2.1e-16 60.2 0.2 7.2e-16 58.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Ski2_N PF17911.1 CDJ92775.1 - 3.1e-15 56.2 0.1 6.5e-15 55.1 0.1 1.4 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 CDJ92775.1 - 3.6e-11 43.5 3.1 8.8e-11 42.2 3.1 1.7 1 0 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.31 CDJ92775.1 - 3.8e-08 33.7 0.0 2.6e-07 31.0 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain MAM PF00629.23 CDJ92776.1 - 0.037 13.9 0.0 0.044 13.7 0.0 1.1 1 0 0 1 1 1 0 MAM domain, meprin/A5/mu DUF4499 PF14934.6 CDJ92778.1 - 1.4e-17 63.8 5.4 1.7e-17 63.5 5.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) EGF_2 PF07974.13 CDJ92779.1 - 0.53 10.7 11.5 3.2 8.2 6.0 2.9 1 1 1 2 2 2 0 EGF-like domain Laminin_EGF PF00053.24 CDJ92779.1 - 1.5 9.0 11.5 6.8 6.9 11.5 2.1 1 1 0 1 1 1 0 Laminin EGF domain hEGF PF12661.7 CDJ92779.1 - 8.4 7.2 14.6 9.7 7.0 2.1 4.1 3 1 0 3 3 3 0 Human growth factor-like EGF Serpin PF00079.20 CDJ92780.1 - 6.1e-90 302.2 3.8 6.8e-90 302.1 3.8 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 CDJ92781.1 - 1.2e-25 90.6 0.0 1.3e-25 90.5 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) ERAP1_C PF11838.8 CDJ92782.1 - 4.1e-36 125.1 0.0 1.4e-24 87.3 0.0 2.0 1 1 1 2 2 2 2 ERAP1-like C-terminal domain CRM1_repeat_3 PF18787.1 CDJ92782.1 - 0.027 14.6 0.2 2.5 8.3 0.0 2.5 2 0 0 2 2 2 0 CRM1 / Exportin repeat 3 Gryzun-like PF12742.7 CDJ92782.1 - 0.085 12.9 0.2 8.1 6.5 0.0 2.8 2 1 1 3 3 3 0 Gryzun, putative Golgi trafficking TetR_C_27 PF17935.1 CDJ92782.1 - 0.097 12.7 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HCO3_cotransp PF00955.21 CDJ92784.1 - 6.4e-110 368.4 11.4 7.4e-99 331.9 2.0 2.1 1 1 1 2 2 2 2 HCO3- transporter family Band_3_cyto PF07565.13 CDJ92784.1 - 4.7e-40 138.1 0.1 9.3e-39 133.8 0.1 2.3 1 1 0 1 1 1 1 Band 3 cytoplasmic domain Hs1pro-1_N PF07231.12 CDJ92784.1 - 0.18 11.5 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Hs1pro-1 N-terminus Erf4 PF10256.9 CDJ92785.1 - 1.2e-27 96.4 0.3 2e-27 95.6 0.1 1.5 2 0 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family Anoctamin PF04547.12 CDJ92786.1 - 1.1e-138 462.8 7.8 1.4e-138 462.5 7.8 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel FtsH_ext PF06480.15 CDJ92786.1 - 0.097 13.0 0.8 20 5.6 0.2 3.0 3 0 0 3 3 3 0 FtsH Extracellular TatC PF00902.18 CDJ92786.1 - 0.58 9.9 7.9 0.36 10.6 4.5 2.2 2 0 0 2 2 2 0 Sec-independent protein translocase protein (TatC) SLC3A2_N PF16028.5 CDJ92786.1 - 1.4 8.5 4.2 4.5 6.9 0.3 2.8 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus Ctr PF04145.15 CDJ92787.1 - 1.6e-24 87.2 14.5 3e-14 53.9 3.8 2.0 1 1 1 2 2 2 2 Ctr copper transporter family Phtf-FEM1B_bdg PF12129.8 CDJ92787.1 - 4 7.3 8.5 8.9 6.1 0.8 2.2 1 1 1 2 2 2 0 Male germ-cell putative homeodomain transcription factor DUF4191 PF13829.6 CDJ92787.1 - 4.6 6.5 4.5 0.67 9.3 0.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Shisa PF13908.6 CDJ92789.1 - 0.0068 16.7 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Cadherin PF00028.17 CDJ92791.1 - 1.9e-60 201.3 0.1 6.4e-17 61.8 0.0 5.1 5 0 0 5 5 5 5 Cadherin domain Cadherin_3 PF16184.5 CDJ92791.1 - 0.00012 22.1 3.8 2.2 8.3 0.0 4.3 4 1 0 4 4 4 3 Cadherin-like Cadherin_2 PF08266.12 CDJ92791.1 - 0.0011 18.7 0.0 33 4.4 0.0 4.1 4 0 0 4 4 4 2 Cadherin-like PepSY PF03413.19 CDJ92791.1 - 0.066 13.8 0.0 0.61 10.7 0.0 2.6 2 1 0 2 2 2 0 Peptidase propeptide and YPEB domain DUF3364 PF11844.8 CDJ92791.1 - 0.12 12.6 0.2 18 5.7 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3364) Fringe PF02434.16 CDJ92792.1 - 8e-05 22.2 0.1 0.0009 18.7 0.1 2.4 2 1 0 2 2 2 1 Fringe-like Galactosyl_T PF01762.21 CDJ92792.1 - 0.00023 21.0 0.0 0.4 10.5 0.0 2.1 1 1 1 2 2 2 2 Galactosyltransferase zf-C4 PF00105.18 CDJ92793.1 - 1.9e-27 95.5 11.0 4.5e-27 94.3 11.0 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ92793.1 - 2.6e-20 72.9 0.0 4.2e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Macoilin PF09726.9 CDJ92794.1 - 0.079 11.5 24.4 0.082 11.5 24.4 1.0 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 CDJ92794.1 - 0.25 10.2 20.3 0.3 9.9 20.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM76 PF16046.5 CDJ92794.1 - 0.35 10.2 22.0 0.43 9.9 22.0 1.2 1 0 0 1 1 1 0 FAM76 protein TFIIF_alpha PF05793.12 CDJ92794.1 - 0.65 8.5 22.2 0.75 8.3 22.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ASD2 PF08687.11 CDJ92794.1 - 0.97 8.9 11.1 1.2 8.6 11.1 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 FAM60A PF15396.6 CDJ92794.1 - 1.1 9.2 17.1 1.3 9.0 17.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CDC45 PF02724.14 CDJ92794.1 - 2.2 6.5 16.9 2.5 6.3 16.9 1.0 1 0 0 1 1 1 0 CDC45-like protein ALMT PF11744.8 CDJ92794.1 - 2.5 6.9 12.0 2.8 6.7 12.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 CDJ92794.1 - 3.3 6.6 15.4 3.8 6.4 15.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 GREB1 PF15782.5 CDJ92794.1 - 3.4 4.7 13.9 3.3 4.7 13.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Mem_trans PF03547.18 CDJ92794.1 - 4.2 5.7 9.5 5.2 5.3 9.5 1.1 1 0 0 1 1 1 0 Membrane transport protein MCM_bind PF09739.9 CDJ92794.1 - 5.5 5.3 14.7 6.4 5.1 14.7 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Presenilin PF01080.17 CDJ92794.1 - 6.6 5.4 18.1 7.6 5.2 18.1 1.1 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 CDJ92794.1 - 6.7 5.4 14.7 7.3 5.3 14.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Kinesin PF00225.23 CDJ92795.1 - 3.1e-94 315.6 0.0 4.9e-94 315.0 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain MKLP1_Arf_bdg PF16540.5 CDJ92795.1 - 7.3e-32 109.6 0.0 1.7e-31 108.5 0.0 1.6 1 0 0 1 1 1 1 Arf6-interacting domain of mitotic kinesin-like protein 1 Microtub_bd PF16796.5 CDJ92795.1 - 5.3e-16 58.9 0.0 2.9e-14 53.3 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding Tnp_22_trimer PF17489.2 CDJ92795.1 - 0.11 12.4 1.9 0.3 11.1 1.9 1.8 1 0 0 1 1 1 0 L1 transposable element trimerization domain GAS PF13851.6 CDJ92795.1 - 0.11 11.8 9.4 0.014 14.7 4.4 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding RRP36 PF06102.12 CDJ92795.1 - 0.27 11.2 7.4 0.91 9.5 7.4 1.9 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 Spc7 PF08317.11 CDJ92795.1 - 0.37 9.6 7.2 0.7 8.7 7.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 CDJ92795.1 - 5.2 7.8 5.6 3.2 8.4 2.8 2.1 2 0 0 2 2 2 0 Initiation control protein YabA Atg14 PF10186.9 CDJ92795.1 - 6.7 5.7 9.3 6.6 5.7 7.0 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 tRNA-synt_2 PF00152.20 CDJ92796.1 - 3.3e-98 328.7 0.0 4.2e-98 328.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CDJ92796.1 - 6e-11 42.2 0.0 1.4e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Mito_fiss_reg PF05308.11 CDJ92796.1 - 0.08 13.0 0.3 0.48 10.5 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator THOC7 PF05615.13 CDJ92796.1 - 0.15 12.3 2.3 0.41 10.9 2.3 1.7 1 0 0 1 1 1 0 Tho complex subunit 7 Aa_trans PF01490.18 CDJ92797.1 - 1.2e-06 27.5 0.4 1.3e-06 27.4 0.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CDJ92797.1 - 0.0016 17.6 4.7 0.0018 17.4 4.7 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Lectin_C PF00059.21 CDJ92798.1 - 4.1e-09 37.1 0.1 4.1e-09 37.1 0.1 3.1 3 1 0 3 3 3 1 Lectin C-type domain Acyltransf_C PF16076.5 CDJ92799.1 - 0.029 14.4 0.1 0.052 13.6 0.1 1.4 1 0 0 1 1 1 0 Acyltransferase C-terminus Astacin PF01400.24 CDJ92801.1 - 3.8e-11 43.0 0.0 4.4e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Astacin PF01400.24 CDJ92802.1 - 3.9e-53 179.9 0.8 4.8e-53 179.6 0.8 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) ShK PF01549.24 CDJ92802.1 - 1.4e-08 35.1 6.6 2.5e-08 34.3 6.6 1.4 1 0 0 1 1 1 1 ShK domain-like CAP_N PF01213.19 CDJ92802.1 - 0.0054 16.3 2.7 0.0076 15.8 2.7 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 CDJ92802.1 - 1.8 8.6 6.2 2.5 8.1 6.2 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator RRM_1 PF00076.22 CDJ92803.1 - 5.5e-13 48.5 0.1 8.5e-06 25.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acetyltransf_1 PF00583.25 CDJ92804.1 - 9.6e-15 54.8 0.0 1.4e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDJ92804.1 - 5.5e-09 36.3 0.0 9.4e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDJ92804.1 - 5.9e-09 35.9 0.1 9.4e-09 35.3 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDJ92804.1 - 4.4e-06 26.6 0.1 9e-06 25.6 0.1 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 CDJ92804.1 - 0.0013 18.3 0.9 0.0024 17.4 0.1 1.8 1 1 0 2 2 2 1 Putative acetyl-transferase Acetyltransf_3 PF13302.7 CDJ92804.1 - 0.0031 18.2 0.0 0.0057 17.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 CDJ92804.1 - 0.02 14.9 0.1 0.036 14.0 0.1 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_9 PF13527.7 CDJ92804.1 - 0.023 14.8 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 CDJ92804.1 - 0.072 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ MgtE PF01769.16 CDJ92805.1 - 5e-47 159.3 21.4 6.8e-24 84.6 3.3 2.9 3 0 0 3 3 3 2 Divalent cation transporter CAP_GLY PF01302.25 CDJ92805.1 - 3.5e-17 62.2 2.6 6.6e-17 61.3 2.6 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 CDJ92805.1 - 1.8e-09 37.7 11.3 0.14 12.6 0.2 4.7 3 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDJ92805.1 - 3.9e-07 29.7 0.1 0.01 15.3 0.0 2.4 2 0 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 CDJ92805.1 - 1.4e-05 24.8 0.3 2.4 8.0 0.0 4.2 3 1 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 CDJ92805.1 - 6e-05 22.8 0.9 2.8 8.2 0.1 4.6 4 0 0 4 4 4 1 Leucine Rich repeat DUF717 PF05338.12 CDJ92805.1 - 0.15 12.2 0.2 0.42 10.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF717) LRR_1 PF00560.33 CDJ92805.1 - 1.4 9.7 8.3 25 6.0 0.0 5.8 6 1 0 6 6 6 0 Leucine Rich Repeat Cyclin_N PF00134.23 CDJ92806.1 - 3.6e-12 46.1 0.1 5.6e-09 35.8 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain WD40 PF00400.32 CDJ92807.1 - 5.9e-19 68.1 17.5 0.015 16.1 0.2 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ92807.1 - 0.0031 17.8 8.8 0.16 12.3 0.6 4.1 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain HRM PF02793.22 CDJ92807.1 - 0.017 15.4 2.3 0.038 14.3 0.0 2.7 3 0 0 3 3 3 0 Hormone receptor domain V_ATPase_I PF01496.19 CDJ92808.1 - 1.6e-295 982.3 1.6 1.8e-295 982.1 1.6 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DDE_3 PF13358.6 CDJ92809.1 - 4.7e-05 23.2 0.0 6.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Kinase-like PF14531.6 CDJ92810.1 - 0.13 11.5 0.0 0.14 11.4 0.0 1.0 1 0 0 1 1 1 0 Kinase-like CAP PF00188.26 CDJ92811.1 - 7.1e-10 39.8 0.3 7.1e-10 39.8 0.3 1.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ92811.1 - 0.038 14.3 0.3 0.093 13.0 0.0 1.9 1 1 1 2 2 2 0 Ancylostoma-associated secreted protein related SH3_9 PF14604.6 CDJ92812.1 - 6e-12 45.2 0.0 9.8e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDJ92812.1 - 2.2e-08 33.6 0.0 3.1e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDJ92812.1 - 6.6e-07 28.9 0.0 1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain XFP PF03894.15 CDJ92812.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Sre PF03125.18 CDJ92813.1 - 9.3e-22 77.7 8.9 1.2e-21 77.3 8.9 1.1 1 0 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor 7TM_GPCR_Srab PF10292.9 CDJ92813.1 - 0.0067 15.4 6.1 0.0089 15.0 6.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor tRNA_lig_kinase PF08303.11 CDJ92813.1 - 0.38 10.8 3.8 0.17 12.0 1.1 1.7 2 0 0 2 2 2 0 tRNA ligase kinase domain ShK PF01549.24 CDJ92814.1 - 0.017 15.7 3.1 0.029 14.9 3.1 1.3 1 0 0 1 1 1 0 ShK domain-like Neur_chan_LBD PF02931.23 CDJ92815.1 - 3.7e-13 49.4 0.6 5.6e-13 48.8 0.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain 7TM_GPCR_Srx PF10328.9 CDJ92817.1 - 1.1e-05 25.2 8.7 1.3e-05 25.0 8.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF621 PF04789.15 CDJ92817.1 - 3.9e-05 23.0 4.8 5e-05 22.6 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF621) Spo7 PF03907.13 CDJ92817.1 - 0.006 16.1 0.4 0.01 15.4 0.4 1.3 1 0 0 1 1 1 1 Spo7-like protein 7TM_GPCR_Srab PF10292.9 CDJ92818.1 - 1.8e-20 73.1 8.9 2e-20 73.0 8.9 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Sra PF02117.16 CDJ92818.1 - 1.8e-16 59.9 12.4 2e-16 59.8 12.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sra MHYT PF03707.16 CDJ92818.1 - 1 9.6 4.4 3.1 8.0 0.0 2.9 2 1 1 3 3 3 0 Bacterial signalling protein N terminal repeat DUF4064 PF13273.6 CDJ92818.1 - 1.9 8.8 10.6 9.1 6.6 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) HLH PF00010.26 CDJ92821.1 - 0.0034 17.3 0.0 0.0066 16.4 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Peptidase_A17 PF05380.13 CDJ92823.1 - 6.6e-27 94.5 1.2 1.3e-26 93.5 0.2 2.0 2 0 0 2 2 2 1 Pao retrotransposon peptidase DUF5641 PF18701.1 CDJ92823.1 - 8.3e-18 64.3 0.6 2.6e-17 62.8 0.6 1.9 1 0 0 1 1 1 1 Family of unknown function (DUF5641) DUF1759 PF03564.15 CDJ92823.1 - 1.2e-08 35.0 1.0 2.9e-08 33.8 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 CDJ92823.1 - 1.4e-07 31.5 0.0 2.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) RVT_1 PF00078.27 CDJ92823.1 - 9.8e-07 28.5 0.1 2e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CDJ92823.1 - 5.8e-05 23.6 0.0 0.00023 21.7 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease rve PF00665.26 CDJ92823.1 - 0.0011 19.1 0.0 0.0039 17.4 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 CDJ92823.1 - 0.0012 19.3 0.0 0.004 17.7 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease NPDC1 PF06809.11 CDJ92823.1 - 0.11 11.6 0.1 0.2 10.7 0.1 1.4 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) Svf1 PF08622.10 CDJ92823.1 - 0.14 12.2 0.1 0.4 10.7 0.0 1.8 2 0 0 2 2 2 0 Svf1-like N-terminal lipocalin domain HTH_Tnp_Tc3_2 PF01498.18 CDJ92824.1 - 3.9e-11 43.0 1.7 8.3e-11 42.0 1.7 1.5 1 0 0 1 1 1 1 Transposase PAX PF00292.18 CDJ92824.1 - 0.0002 21.3 0.5 0.00033 20.6 0.5 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 CDJ92824.1 - 0.029 14.2 1.0 0.093 12.6 0.1 2.2 2 0 0 2 2 2 0 Homeodomain-like domain COE1_DBD PF16422.5 CDJ92825.1 - 6.7e-122 405.3 0.5 9.1e-122 404.9 0.5 1.1 1 0 0 1 1 1 1 Transcription factor COE1 DNA-binding domain COE1_HLH PF16423.5 CDJ92825.1 - 9.1e-28 95.7 0.6 1.5e-27 95.0 0.6 1.4 1 0 0 1 1 1 1 Transcription factor COE1 helix-loop-helix domain TIG PF01833.24 CDJ92825.1 - 2.8e-10 40.1 0.1 5.3e-10 39.2 0.1 1.5 1 0 0 1 1 1 1 IPT/TIG domain RHD_dimer PF16179.5 CDJ92825.1 - 0.0085 16.1 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Rel homology dimerisation domain Collagen PF01391.18 CDJ92827.1 - 8.5e-221 714.0 811.1 1.7e-09 37.3 29.4 29.7 3 3 23 27 27 27 26 Collagen triple helix repeat (20 copies) C4 PF01413.19 CDJ92827.1 - 2.4e-84 279.0 3.6 1.2e-44 151.2 0.2 2.1 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen COesterase PF00135.28 CDJ92828.1 - 1.7e-39 136.1 1.6 2.2e-39 135.7 1.6 1.1 1 0 0 1 1 1 1 Carboxylesterase family AChE_tetra PF08674.10 CDJ92828.1 - 0.22 11.2 9.8 1.1 9.1 9.8 2.2 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain Motile_Sperm PF00635.26 CDJ92829.1 - 5.9e-15 55.0 0.5 7.2e-15 54.8 0.5 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Cytadhesin_P30 PF07271.11 CDJ92829.1 - 0.013 15.1 0.8 0.013 15.1 0.8 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 DUF5001 PF16392.5 CDJ92829.1 - 0.072 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Ig-like domain CAP PF00188.26 CDJ92831.1 - 2.5e-32 112.4 15.1 7.9e-17 62.3 1.3 2.4 2 0 0 2 2 2 2 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ92831.1 - 0.0004 20.7 4.5 0.19 12.0 0.1 3.0 2 1 0 2 2 2 2 Ancylostoma-associated secreted protein related Pilin_PilA PF14245.6 CDJ92831.1 - 0.11 12.5 2.1 0.12 12.3 0.2 2.2 2 0 0 2 2 2 0 Type IV pilin PilA Metallothio_Euk PF12749.7 CDJ92831.1 - 0.13 12.4 20.3 1.3 9.2 5.8 2.8 2 0 0 2 2 2 0 Eukaryotic metallothionein Metallothio_PEC PF02068.16 CDJ92831.1 - 2.1 8.7 23.6 1.8 8.9 9.6 2.8 2 0 0 2 2 2 0 Plant PEC family metallothionein Arf PF00025.21 CDJ92833.1 - 1.8e-80 268.5 0.1 2.1e-80 268.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CDJ92833.1 - 1.5e-14 54.0 1.8 1.2e-10 41.1 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 CDJ92833.1 - 1.8e-14 54.0 0.0 2.5e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CDJ92833.1 - 3.7e-14 52.6 0.0 4.6e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CDJ92833.1 - 1.1e-12 47.8 0.0 1.3e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CDJ92833.1 - 1.8e-11 43.8 0.0 2.3e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDJ92833.1 - 1.8e-07 31.3 0.1 1.9e-06 27.9 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CDJ92833.1 - 0.0034 16.7 0.2 0.013 14.8 0.1 1.8 2 0 0 2 2 2 1 6-phosphofructo-2-kinase cobW PF02492.19 CDJ92833.1 - 0.17 11.5 0.2 1.2 8.7 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Acetyltransf_16 PF05301.11 CDJ92834.1 - 3.4e-29 101.8 0.0 4.8e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_7 PF13508.7 CDJ92834.1 - 0.048 14.1 0.0 0.074 13.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 CDJ92835.1 - 3.6e-49 167.6 23.5 1.6e-48 165.4 19.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CDJ92835.1 - 0.016 13.5 8.4 0.034 12.4 8.1 1.7 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family IF4E PF01652.18 CDJ92836.1 - 1.4e-53 180.9 0.3 1.8e-53 180.6 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Kunitz_BPTI PF00014.23 CDJ92837.1 - 5.4e-145 471.6 90.3 1.5e-17 63.6 1.3 9.6 9 0 0 9 9 9 9 Kunitz/Bovine pancreatic trypsin inhibitor domain Lustrin_cystein PF14625.6 CDJ92837.1 - 5.8e-32 109.8 111.3 1.2e-10 41.5 6.1 10.4 9 1 0 9 9 9 6 Lustrin, cysteine-rich repeated domain MCR_alpha PF02249.17 CDJ92837.1 - 0.077 13.4 1.1 3.6 8.1 0.0 3.2 4 0 0 4 4 4 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain G-patch PF01585.23 CDJ92838.1 - 1.3e-13 50.6 4.2 2.5e-13 49.7 4.2 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CDJ92838.1 - 0.00055 20.0 0.1 0.0018 18.3 0.1 1.9 1 0 0 1 1 1 1 G-patch domain INCENP_ARK-bind PF03941.15 CDJ92838.1 - 0.081 12.9 1.8 12 5.9 1.6 3.0 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region Prok-E2_A PF14457.6 CDJ92839.1 - 0.0054 16.4 0.3 0.0074 15.9 0.3 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family A PRIMA1 PF16101.5 CDJ92839.1 - 0.13 12.3 2.2 0.21 11.7 2.2 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF2632 PF10943.8 CDJ92840.1 - 0.069 12.7 1.7 0.073 12.6 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2632) UDPGT PF00201.18 CDJ92841.1 - 1e-06 27.9 1.1 0.00085 18.2 0.1 3.2 2 2 1 3 3 3 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_4 PF13439.6 CDJ92841.1 - 0.13 12.2 0.0 0.35 10.9 0.0 1.8 1 1 0 1 1 1 0 Glycosyltransferase Family 4 UDPGT PF00201.18 CDJ92842.1 - 1.1e-33 116.9 0.1 2.1e-33 115.9 0.1 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ92842.1 - 6e-06 26.3 0.0 1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain BACK PF07707.15 CDJ92846.1 - 1.3e-07 31.7 3.5 1.8e-07 31.2 1.8 2.1 3 0 0 3 3 3 1 BTB And C-terminal Kelch Nup84_Nup100 PF04121.13 CDJ92846.1 - 0.00024 19.4 0.4 0.00029 19.1 0.4 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 NOG1 PF06858.14 CDJ92846.1 - 0.048 13.5 0.4 0.55 10.1 0.0 2.7 3 0 0 3 3 3 0 Nucleolar GTP-binding protein 1 (NOG1) zf-RING_2 PF13639.6 CDJ92848.1 - 5.2e-08 33.1 11.3 2.4e-07 31.0 11.3 2.3 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 CDJ92848.1 - 3.1e-06 27.1 4.7 7.4e-06 25.9 4.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 CDJ92848.1 - 3.9e-05 23.7 7.2 0.00014 22.0 7.2 2.0 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 CDJ92848.1 - 0.00054 20.2 11.5 0.0017 18.6 11.5 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain RINGv PF12906.7 CDJ92848.1 - 0.0015 18.6 11.5 0.0048 17.0 11.5 1.9 1 0 0 1 1 1 1 RING-variant domain Zf_RING PF16744.5 CDJ92848.1 - 0.036 14.2 4.9 0.13 12.3 4.9 2.1 1 0 0 1 1 1 0 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 CDJ92848.1 - 0.038 13.6 8.1 0.089 12.4 8.1 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 CDJ92848.1 - 0.054 13.4 13.5 0.16 11.8 13.5 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2318 PF10080.9 CDJ92848.1 - 0.058 13.5 0.8 0.14 12.3 0.8 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) YcbB PF08664.10 CDJ92848.1 - 0.067 13.2 0.0 0.24 11.5 0.0 1.9 1 0 0 1 1 1 0 YcbB domain zf-C3HC4_2 PF13923.6 CDJ92848.1 - 0.093 12.6 11.6 0.25 11.2 11.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 CDJ92848.1 - 0.49 10.7 10.8 1.9 8.8 10.8 2.2 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 CDJ92848.1 - 1.3 8.9 6.4 3.9 7.3 6.4 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DED PF01335.21 CDJ92848.1 - 1.4 9.3 3.9 2.9 8.2 1.2 2.8 2 0 0 2 2 2 0 Death effector domain C1_1 PF00130.22 CDJ92848.1 - 1.5 8.8 13.5 0.051 13.5 6.7 2.2 2 1 0 2 2 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Sec7_N PF12783.7 CDJ92848.1 - 1.6 8.6 8.0 3.2 7.6 0.4 3.9 3 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal PHD PF00628.29 CDJ92848.1 - 4.1 7.4 13.9 1.4 8.9 9.9 2.4 2 0 0 2 2 2 0 PHD-finger zf-RING_9 PF13901.6 CDJ92848.1 - 8.3 6.3 12.9 4.1 7.3 8.9 2.6 3 0 0 3 3 2 0 Putative zinc-RING and/or ribbon Big_2 PF02368.18 CDJ92849.1 - 1e-12 47.7 13.4 0.0001 22.1 0.3 7.1 6 1 1 7 7 7 3 Bacterial Ig-like domain (group 2) T2SS-T3SS_pil_N PF13629.6 CDJ92849.1 - 0.0016 18.1 6.1 1.4 8.7 0.1 4.8 5 0 0 5 5 5 2 Pilus formation protein N terminal region Pkinase PF00069.25 CDJ92851.1 - 2e-27 96.3 0.0 3.7e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ92851.1 - 4.4e-14 52.4 0.0 8.4e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ92851.1 - 0.0019 17.0 0.0 0.0019 17.0 0.0 3.4 2 1 0 2 2 2 1 Fungal protein kinase RRM_1 PF00076.22 CDJ92852.1 - 1.1e-17 63.6 0.4 4.4e-17 61.7 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ92852.1 - 0.00014 21.5 0.0 0.00016 21.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_6 PF13174.6 CDJ92852.1 - 0.00081 19.9 0.5 0.0017 18.9 0.5 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Brix PF04427.18 CDJ92853.1 - 5.6e-31 108.1 0.3 9.5e-31 107.4 0.3 1.4 1 0 0 1 1 1 1 Brix domain Hexapep PF00132.24 CDJ92854.1 - 3.8e-05 23.2 17.4 0.031 14.0 0.1 4.5 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CDJ92854.1 - 1.5 8.7 15.4 0.18 11.6 0.5 4.2 3 2 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase Synaphin PF05835.12 CDJ92855.1 - 1.1e-37 129.5 8.4 1.1e-37 129.5 8.4 2.1 2 0 0 2 2 2 1 Synaphin protein FHA PF00498.26 CDJ92855.1 - 1.8e-10 41.0 0.0 3.1e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 FHA domain TH1 PF04858.13 CDJ92856.1 - 7.4e-57 193.3 2.6 2.4e-56 191.6 2.6 1.8 1 1 0 1 1 1 1 TH1 protein Tim54 PF11711.8 CDJ92856.1 - 0.0068 15.2 0.4 0.0094 14.8 0.4 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 p450 PF00067.22 CDJ92856.1 - 0.016 13.9 0.5 0.023 13.4 0.0 1.4 2 0 0 2 2 2 0 Cytochrome P450 Methyltransf_7 PF03492.15 CDJ92856.1 - 0.16 11.1 0.3 1.2 8.2 0.1 2.0 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase RR_TM4-6 PF06459.12 CDJ92856.1 - 5.1 6.8 10.3 0.63 9.8 6.1 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 CDJ92856.1 - 5.3 7.5 8.3 10 6.6 8.3 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 BolA PF01722.18 CDJ92857.1 - 1.1e-13 51.3 0.0 3e-13 49.8 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein DUF3725 PF12523.8 CDJ92857.1 - 0.075 13.3 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) Pribosyltran_N PF13793.6 CDJ92858.1 - 1.6e-45 153.8 1.1 1.5e-44 150.7 0.2 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CDJ92858.1 - 4.5e-44 150.7 0.5 2.3e-37 128.8 0.1 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CDJ92858.1 - 3e-14 52.8 0.5 5.5e-14 52.0 0.1 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CDJ92858.1 - 0.00012 21.6 0.0 0.00028 20.4 0.0 1.5 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase FERM_C PF09380.10 CDJ92859.1 - 6.5e-23 80.9 0.1 1.3e-22 79.9 0.1 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 CDJ92859.1 - 3.3e-21 75.9 3.9 2.6e-20 73.0 0.1 2.2 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.10 CDJ92859.1 - 1.3e-11 44.2 0.0 3.1e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain ERM PF00769.19 CDJ92859.1 - 5.9e-06 26.3 19.0 5.9e-06 26.3 19.0 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family ACBP PF00887.19 CDJ92859.1 - 0.02 15.1 0.3 0.054 13.7 0.0 1.9 2 0 0 2 2 2 0 Acyl CoA binding protein DUF1664 PF07889.12 CDJ92859.1 - 1.9 8.5 5.3 3.2 7.8 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Asp-B-Hydro_N PF05279.11 CDJ92859.1 - 2.8 7.9 10.2 4 7.4 10.2 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Seryl_tRNA_N PF02403.22 CDJ92859.1 - 4 7.7 16.8 7.4 6.9 16.8 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain RVT_1 PF00078.27 CDJ92861.1 - 9e-11 41.7 0.0 1.3e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ADK_lid PF05191.14 CDJ92862.1 - 1.2e-15 57.1 0.0 2e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid ADK PF00406.22 CDJ92862.1 - 7.1e-09 35.9 0.0 8.9e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase Collagen PF01391.18 CDJ92863.1 - 1.1e-13 50.7 56.7 1e-07 31.6 56.7 2.6 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) RVT_1 PF00078.27 CDJ92864.1 - 2.7e-06 27.1 0.0 4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UDPGT PF00201.18 CDJ92865.1 - 1.5e-119 400.1 0.0 5.3e-69 233.3 0.0 2.0 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ92865.1 - 3.2e-31 108.5 0.0 3.4e-14 53.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 CDJ92865.1 - 8.5e-10 38.4 0.0 0.00036 19.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 1 MazG_C PF18722.1 CDJ92865.1 - 0.013 15.0 0.4 7.4 6.0 0.0 2.8 3 0 0 3 3 3 0 MazG C-terminal domain Tombus_P33 PF08500.10 CDJ92865.1 - 0.056 13.4 0.3 0.056 13.4 0.3 1.7 2 0 0 2 2 2 0 Tombusvirus p33 Glyco_transf_4 PF13439.6 CDJ92865.1 - 0.11 12.5 0.0 16 5.5 0.0 2.8 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Glyco_trans_4_2 PF13477.6 CDJ92865.1 - 0.14 12.2 0.2 24 4.9 0.0 3.3 3 0 0 3 3 3 0 Glycosyl transferase 4-like Vfa1 PF08432.10 CDJ92867.1 - 1.6 9.0 12.9 1.7 9.0 12.9 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PPL5 PF18168.1 CDJ92867.1 - 1.7 7.9 9.5 1.7 7.9 9.5 1.0 1 0 0 1 1 1 0 Prim-pol family 5 GP67 PF17634.2 CDJ92867.1 - 2.3 8.7 14.7 3 8.3 14.7 1.3 1 0 0 1 1 1 0 Gene product 67 DUF3464 PF11947.8 CDJ92867.1 - 3.3 7.4 7.3 3.4 7.4 7.3 1.0 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 FAM176 PF14851.6 CDJ92867.1 - 5.9 6.5 7.6 6.2 6.5 7.6 1.1 1 0 0 1 1 1 0 FAM176 family MAP17 PF15807.5 CDJ92867.1 - 6.6 7.0 8.0 6.9 6.9 8.0 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 TF_Otx PF03529.13 CDJ92868.1 - 0.046 14.1 2.9 7.3 7.1 0.2 2.5 1 1 1 2 2 2 0 Otx1 transcription factor Ribophorin_I PF04597.14 CDJ92869.1 - 1.7e-133 446.1 5.3 2.1e-133 445.8 5.3 1.1 1 0 0 1 1 1 1 Ribophorin I 7TM_GPCR_Srw PF10324.9 CDJ92871.1 - 7.8e-41 140.4 20.8 1.1e-40 139.9 20.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 CDJ92871.1 - 0.00015 21.2 17.2 0.00043 19.7 17.2 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Mx_ML PF17536.2 CDJ92871.1 - 0.015 15.0 0.1 0.03 14.0 0.1 1.6 1 0 0 1 1 1 0 Matrix and Matrix long proteins N-terminal DNA_primase_S PF01896.19 CDJ92872.1 - 9.9e-49 165.8 0.1 2.1e-48 164.7 0.1 1.6 1 0 0 1 1 1 1 DNA primase small subunit HEAT PF02985.22 CDJ92873.1 - 1.7e-06 27.8 6.6 0.33 11.3 0.0 6.8 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 CDJ92873.1 - 0.023 15.2 1.3 18 6.0 0.1 4.1 3 0 0 3 3 3 0 HEAT-like repeat Phage_BR0599 PF09356.10 CDJ92873.1 - 0.11 12.8 0.1 0.28 11.5 0.1 1.6 1 0 0 1 1 1 0 Phage conserved hypothetical protein BR0599 Aminotran_5 PF00266.19 CDJ92874.1 - 1e-49 169.5 0.0 1.2e-49 169.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CDJ92874.1 - 0.00043 19.6 0.0 0.36 10.0 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Lipase_GDSL PF00657.22 CDJ92875.1 - 1.7e-12 47.8 0.0 2.6e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 CDJ92875.1 - 1.6e-05 25.4 0.1 0.00026 21.4 0.1 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family RNA_pol_Rpb1_2 PF00623.20 CDJ92876.1 - 4.3e-59 199.4 0.1 1.1e-58 198.1 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CDJ92876.1 - 1.4e-30 106.3 0.0 4.6e-30 104.6 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 CDJ92876.1 - 7.6e-19 68.2 11.2 4.5e-18 65.7 0.3 3.3 3 1 0 3 3 3 2 RNA polymerase Rpb1, domain 1 CAP PF00188.26 CDJ92879.1 - 1.5e-17 64.6 4.5 2.2e-17 64.1 4.5 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ92879.1 - 0.001 19.3 6.0 0.028 14.7 6.0 2.4 1 1 0 1 1 1 1 Ancylostoma-associated secreted protein related Gemini_mov PF01708.16 CDJ92881.1 - 0.11 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Geminivirus putative movement protein m04gp34like PF12216.8 CDJ92881.1 - 0.15 11.6 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Immune evasion protein UL42 PF17638.2 CDJ92883.1 - 0.07 13.1 0.1 0.085 12.8 0.1 1.1 1 0 0 1 1 1 0 HCMV UL42 OSTbeta PF15048.6 CDJ92883.1 - 0.09 12.9 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF4083 PF13314.6 CDJ92883.1 - 0.11 12.5 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) ECSCR PF15820.5 CDJ92884.1 - 0.029 14.2 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator PolyA_pol_RNAbd PF12627.7 CDJ92885.1 - 4.8e-08 32.6 0.1 3.5e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A Atg14 PF10186.9 CDJ92886.1 - 0.33 10.0 3.8 0.4 9.7 3.8 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pox_VLTF3 PF04947.14 CDJ92887.1 - 0.098 12.4 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like PEPCK_N PF17297.2 CDJ92887.1 - 0.15 11.6 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase N-terminal domain Exo_endo_phos_2 PF14529.6 CDJ92888.1 - 0.036 13.9 0.3 0.24 11.3 0.3 2.0 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Rpn9_C PF18261.1 CDJ92888.1 - 0.057 13.0 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Rpn9 C-terminal helix zf-H2C2_2 PF13465.6 CDJ92893.1 - 7e-09 35.7 15.5 2.3e-06 27.8 1.9 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 CDJ92893.1 - 0.00061 19.5 1.9 0.00061 19.5 1.9 3.2 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 CDJ92893.1 - 0.0022 18.4 1.0 0.0022 18.4 1.0 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 CDJ92893.1 - 0.0098 15.5 0.2 0.024 14.3 0.0 1.7 2 0 0 2 2 2 1 Zinc-fingers and homeoboxes C2H2 finger domain GAGA PF09237.11 CDJ92893.1 - 0.016 15.0 1.3 0.016 15.0 1.3 1.9 2 0 0 2 2 2 0 GAGA factor Cwf_Cwc_15 PF04889.12 CDJ92893.1 - 0.039 13.7 2.1 0.049 13.4 2.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-Di19 PF05605.12 CDJ92893.1 - 0.066 13.5 0.5 0.14 12.4 0.5 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 CDJ92893.1 - 0.079 13.8 0.5 0.079 13.8 0.5 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger 7TM_GPCR_Srx PF10328.9 CDJ92894.1 - 2.9e-08 33.7 4.3 3.4e-08 33.4 4.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Srg PF02118.21 CDJ92894.1 - 7.5e-07 29.1 1.6 9.9e-07 28.7 1.6 1.1 1 0 0 1 1 1 1 Srg family chemoreceptor 7TM_GPCR_Srv PF10323.9 CDJ92894.1 - 7.7e-07 28.7 1.6 9.8e-07 28.4 1.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_1 PF00001.21 CDJ92894.1 - 5.2e-05 22.7 0.9 6e-05 22.5 0.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF621 PF04789.15 CDJ92894.1 - 0.0012 18.1 3.7 0.0015 17.8 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF621) 7TM_GPCR_Srbc PF10316.9 CDJ92894.1 - 0.0024 17.4 0.9 0.0031 17.1 0.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc Serpentine_r_xa PF03383.15 CDJ92894.1 - 0.023 14.7 1.4 0.031 14.2 1.4 1.2 1 0 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa RRM_1 PF00076.22 CDJ92895.1 - 4.5e-06 26.4 0.0 1.4e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 7tm_1 PF00001.21 CDJ92896.1 - 2e-13 50.3 26.2 5.2e-13 48.9 25.3 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDJ92896.1 - 1.3e-07 31.2 24.4 2.1e-07 30.5 24.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw VPS9 PF02204.18 CDJ92896.1 - 0.004 17.3 0.2 0.011 15.9 0.2 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF1616 PF07760.11 CDJ92896.1 - 0.042 13.2 0.9 0.07 12.5 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) 7TM_GPCR_Srsx PF10320.9 CDJ92896.1 - 0.18 11.1 28.8 0.35 10.2 28.8 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx gag-asp_proteas PF13975.6 CDJ92897.1 - 2.2e-09 37.7 0.0 7.1e-09 36.1 0.0 2.0 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ92897.1 - 2.7e-08 34.3 0.0 6.4e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ92897.1 - 0.0066 16.7 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease GCIP PF13324.6 CDJ92897.1 - 0.013 15.2 0.0 4.5 6.8 0.0 2.6 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Ima1_N PF09779.9 CDJ92897.1 - 0.018 15.9 6.6 0.023 15.6 4.7 2.2 2 0 0 2 2 2 0 Ima1 N-terminal domain DUF3369 PF11849.8 CDJ92897.1 - 0.021 15.1 0.6 8.3 6.6 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3369) Cas6b_N PF17955.1 CDJ92897.1 - 0.021 14.9 0.1 1.3 9.1 0.1 2.6 1 1 1 2 2 2 0 Cas6b N-terminal domain Pyrid_ox_like PF16242.5 CDJ92897.1 - 0.1 12.2 0.0 9.2 5.8 0.0 2.5 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase like Asp_protease PF09668.10 CDJ92897.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease HscB_4_cys PF18256.1 CDJ92897.1 - 0.25 11.2 9.6 0.53 10.1 9.6 1.6 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif zf-CCHC PF00098.23 CDJ92897.1 - 2.6 8.3 13.1 8.6 6.6 4.4 2.9 2 1 0 2 2 2 0 Zinc knuckle Phage_TTP_1 PF04630.12 CDJ92899.1 - 0.096 12.0 0.2 0.14 11.5 0.2 1.2 1 0 0 1 1 1 0 Phage tail tube protein Exo70 PF03081.15 CDJ92900.1 - 4.7e-47 160.9 1.4 4.7e-47 160.9 1.4 1.7 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Sec34 PF04136.15 CDJ92900.1 - 5.8e-06 26.2 1.9 2.5e-05 24.2 1.9 2.1 1 1 0 1 1 1 1 Sec34-like family Exonuc_VII_L PF02601.15 CDJ92900.1 - 0.3 10.6 5.9 0.19 11.3 2.8 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit NUDIX PF00293.28 CDJ92901.1 - 2.8e-12 46.8 0.1 1.9e-11 44.1 0.1 2.0 1 1 0 1 1 1 1 NUDIX domain KorB PF08535.10 CDJ92901.1 - 0.16 12.0 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 KorB domain 7TM_GPCR_Srw PF10324.9 CDJ92902.1 - 9e-05 21.9 0.3 9.7e-05 21.8 0.3 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 CDJ92902.1 - 0.034 13.5 0.6 0.032 13.6 0.6 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) SLC12 PF03522.15 CDJ92903.1 - 8.9e-06 25.0 0.0 1.1e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Solute carrier family 12 Abhydrolase_9_N PF15420.6 CDJ92905.1 - 8.7 6.3 6.6 4.6 7.2 0.2 2.8 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus CH PF00307.31 CDJ92907.1 - 6e-13 48.9 0.7 2.5e-12 46.9 0.0 2.5 3 1 0 3 3 3 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CDJ92907.1 - 5.9e-06 26.0 0.0 1.4e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain IFT57 PF10498.9 CDJ92907.1 - 0.00089 18.3 17.9 0.013 14.5 7.1 2.9 2 1 1 3 3 3 3 Intra-flagellar transport protein 57 DMPK_coil PF08826.10 CDJ92907.1 - 0.0018 18.3 24.2 0.0027 17.8 5.5 4.1 4 0 0 4 4 4 2 DMPK coiled coil domain like DUF3037 PF11236.8 CDJ92907.1 - 0.024 15.0 1.2 0.024 15.0 1.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3037) DUF4168 PF13767.6 CDJ92907.1 - 0.06 14.5 0.2 0.06 14.5 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) Spc7 PF08317.11 CDJ92907.1 - 0.068 12.0 23.5 0.4 9.5 5.0 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein APG12 PF04110.13 CDJ92907.1 - 0.12 12.7 0.3 3.5 8.1 0.1 2.8 2 1 1 3 3 3 0 Ubiquitin-like autophagy protein Apg12 Prominin PF05478.11 CDJ92907.1 - 0.65 7.9 9.9 0.92 7.4 9.9 1.3 1 0 0 1 1 1 0 Prominin Plk4_PB2 PF18409.1 CDJ92907.1 - 0.78 10.5 4.2 2.4 8.9 0.9 2.7 2 1 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 Fez1 PF06818.15 CDJ92907.1 - 1.2 9.6 21.0 4 7.8 18.6 2.5 1 1 1 2 2 2 0 Fez1 Golgin_A5 PF09787.9 CDJ92907.1 - 1.5 8.2 26.6 0.8 9.1 11.9 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 Tup_N PF08581.10 CDJ92907.1 - 2.6 8.4 18.9 0.19 12.0 5.0 3.5 2 1 1 3 3 3 0 Tup N-terminal FAM76 PF16046.5 CDJ92907.1 - 3.8 6.8 17.1 14 4.9 17.2 1.9 1 1 0 1 1 1 0 FAM76 protein PRKCSH-like PF12999.7 CDJ92907.1 - 8.9 6.1 11.4 0.92 9.3 0.7 2.8 2 1 1 3 3 3 0 Glucosidase II beta subunit-like UCH PF00443.29 CDJ92908.1 - 2e-39 135.7 0.0 3.4e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 CDJ92908.1 - 8.1e-22 76.8 3.3 5.8e-21 74.0 2.2 2.3 2 0 0 2 2 2 1 Variant UBP zinc finger zf-UBP PF02148.19 CDJ92908.1 - 9.5e-13 48.3 0.0 9.5e-13 48.3 0.0 3.2 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 CDJ92908.1 - 1.8e-10 40.5 0.6 0.00017 21.4 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 CDJ92908.1 - 5.6e-10 39.3 0.0 6.6e-08 32.5 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase HTH_26 PF13443.6 CDJ92909.1 - 0.013 15.9 0.0 0.027 14.9 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain DUF3602 PF12223.8 CDJ92909.1 - 0.033 14.8 2.2 0.035 14.7 0.7 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF3602) 7TM_GPCR_Srd PF10317.9 CDJ92910.1 - 9.7e-31 107.0 11.3 1.1e-30 106.9 11.3 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Str PF10326.9 CDJ92910.1 - 1.3e-08 34.6 7.5 1.5e-08 34.4 7.5 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srj PF10319.9 CDJ92910.1 - 0.00089 18.7 7.6 0.0012 18.2 7.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Srh PF10318.9 CDJ92910.1 - 0.058 12.4 11.6 0.072 12.1 11.6 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh S4 PF01479.25 CDJ92911.1 - 2.6e-09 36.6 3.1 3.9e-09 36.1 1.1 2.2 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 CDJ92911.1 - 2e-05 25.4 0.3 3.3e-05 24.7 0.2 1.5 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DUF4381 PF14316.6 CDJ92911.1 - 0.094 13.0 0.5 0.13 12.5 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) ADK PF00406.22 CDJ92912.1 - 7.6e-44 149.4 0.0 1.1e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CDJ92912.1 - 3.9e-34 118.0 0.0 6.6e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain LSM PF01423.22 CDJ92912.1 - 5e-15 54.9 0.2 9.7e-15 54.0 0.2 1.4 1 0 0 1 1 1 1 LSM domain AAA_18 PF13238.6 CDJ92912.1 - 6.1e-07 30.0 0.0 1.2e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDJ92912.1 - 0.00044 20.4 0.0 0.0009 19.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 CDJ92912.1 - 0.038 13.7 0.0 5 6.8 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase Cytidylate_kin PF02224.18 CDJ92912.1 - 0.066 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase PseudoU_synth_2 PF00849.22 CDJ92913.1 - 3.8e-22 79.1 0.0 5.6e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase Codanin-1_C PF15296.6 CDJ92914.1 - 0.014 15.5 1.0 0.021 14.9 1.0 1.4 1 0 0 1 1 1 0 Codanin-1 C-terminus RT_RNaseH_2 PF17919.1 CDJ92915.1 - 3.2e-14 52.8 0.0 6.5e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ92915.1 - 1.9e-07 30.8 0.0 3.4e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDJ92915.1 - 0.0009 19.5 0.0 0.0015 18.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 CDJ92916.1 - 1.3e-08 35.3 0.0 3e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ92916.1 - 1.8e-08 34.9 0.0 3.6e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ92916.1 - 0.00029 21.1 0.0 0.00061 20.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease eIF3g PF12353.8 CDJ92916.1 - 0.0028 18.0 1.7 0.0071 16.7 0.2 2.2 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G Asp_protease PF09668.10 CDJ92916.1 - 0.04 13.7 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 CDJ92917.1 - 2.2e-06 27.4 0.0 3.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hemolysin_N PF12563.8 CDJ92917.1 - 0.03 13.9 0.0 0.081 12.5 0.0 1.6 2 0 0 2 2 2 0 Hemolytic toxin N terminal Galactosyl_T PF01762.21 CDJ92918.1 - 2.2e-13 50.5 0.0 4e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Galactosyltransferase DDE_Tnp_1_7 PF13843.6 CDJ92921.1 - 0.024 14.0 0.1 0.029 13.7 0.1 1.1 1 0 0 1 1 1 0 Transposase IS4 SDF PF00375.18 CDJ92922.1 - 3e-100 336.0 22.8 3.7e-100 335.7 22.8 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF3861 PF12977.7 CDJ92923.1 - 0.04 14.1 0.2 0.53 10.5 0.1 2.1 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) Pkinase PF00069.25 CDJ92925.1 - 2.6e-40 138.5 0.0 3.8e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ92925.1 - 9.1e-28 97.2 0.0 3.5e-27 95.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ92925.1 - 0.00013 21.4 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CDJ92925.1 - 0.087 11.8 0.0 0.24 10.3 0.0 1.8 1 1 0 1 1 1 0 Haspin like kinase domain Neur_chan_memb PF02932.16 CDJ92927.1 - 2e-05 24.8 0.0 2.2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF1977 PF09320.11 CDJ92928.1 - 2.6e-29 101.6 0.9 8.1e-29 100.0 0.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 CDJ92928.1 - 1.2e-24 86.2 1.4 2.1e-24 85.4 1.4 1.5 1 0 0 1 1 1 1 DnaJ domain Tmemb_cc2 PF10267.9 CDJ92928.1 - 1 8.4 5.3 2.5 7.1 5.3 1.5 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein MBT PF02820.18 CDJ92929.1 - 6.1e-18 64.9 0.7 3.2e-07 30.6 0.0 4.6 4 0 0 4 4 4 4 mbt repeat SLED PF12140.8 CDJ92929.1 - 2e-12 47.6 0.0 5.4e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 SLED domain SAM_PNT PF02198.16 CDJ92929.1 - 1e-05 25.4 0.1 0.00022 21.1 0.0 2.8 3 0 0 3 3 3 1 Sterile alpha motif (SAM)/Pointed domain SAM_1 PF00536.30 CDJ92929.1 - 0.0011 19.3 0.1 0.0036 17.7 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TatD_DNase PF01026.21 CDJ92930.1 - 6.3e-47 160.1 0.0 8.6e-47 159.7 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Amidohydro_1 PF01979.20 CDJ92930.1 - 0.015 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase family wnt PF00110.19 CDJ92931.1 - 7.4e-91 305.0 16.1 8.6e-91 304.7 16.1 1.0 1 0 0 1 1 1 1 wnt family CPG4 PF15481.6 CDJ92932.1 - 1.2e-18 67.5 13.0 2.8e-18 66.3 7.0 2.2 2 0 0 2 2 2 2 Chondroitin proteoglycan 4 Ad_cyc_g-alpha PF08509.11 CDJ92932.1 - 0.031 14.0 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Adenylate cyclase G-alpha binding domain CPG4 PF15481.6 CDJ92933.1 - 6.9e-18 65.1 7.8 7e-18 65.0 5.5 2.0 2 0 0 2 2 2 1 Chondroitin proteoglycan 4 Cyclin_N PF00134.23 CDJ92934.1 - 5.4e-06 26.2 0.2 9.6e-06 25.4 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CDJ92934.1 - 0.0034 17.5 0.6 0.04 14.0 0.0 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain Homeodomain PF00046.29 CDJ92935.1 - 1.5e-22 79.2 6.0 2.3e-22 78.6 6.0 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ92935.1 - 0.00018 21.3 1.1 0.00034 20.4 0.6 1.8 1 1 0 1 1 1 1 Homeobox KN domain CBP_BcsR PF10945.8 CDJ92935.1 - 0.045 13.2 0.1 0.089 12.3 0.1 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsR WSD PF15613.6 CDJ92936.1 - 2e-08 34.6 0.2 2e-08 34.6 0.2 3.6 3 1 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD PF00628.29 CDJ92936.1 - 1.8e-07 30.9 5.1 5.8e-07 29.3 5.1 1.9 1 0 0 1 1 1 1 PHD-finger WAC_Acf1_DNA_bd PF10537.9 CDJ92936.1 - 1.8e-05 25.2 2.8 2.2e-05 24.9 0.1 2.6 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal DUF5097 PF17020.5 CDJ92936.1 - 0.00015 22.1 0.8 0.0077 16.6 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF5097) PHD_2 PF13831.6 CDJ92936.1 - 0.00083 18.9 3.4 0.0021 17.6 3.4 1.7 1 0 0 1 1 1 1 PHD-finger DUF2300 PF10062.9 CDJ92936.1 - 0.026 14.6 0.9 0.087 12.9 0.9 1.9 1 0 0 1 1 1 0 Predicted secreted protein (DUF2300) PHD_4 PF16866.5 CDJ92936.1 - 1.9 8.7 6.8 10 6.3 6.8 2.4 1 0 0 1 1 1 0 PHD-finger zf-H2C2_5 PF13909.6 CDJ92937.1 - 0.079 12.7 0.1 0.32 10.8 0.1 2.2 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-Di19 PF05605.12 CDJ92937.1 - 1.3 9.3 5.1 12 6.3 5.2 2.2 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding V_ATPase_I PF01496.19 CDJ92938.1 - 4e-283 941.3 7.9 1.1e-281 936.5 7.9 2.0 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF3480 PF11979.8 CDJ92938.1 - 0.042 12.8 0.0 2.1 7.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3480) Clc-like PF07062.12 CDJ92939.1 - 1.6e-83 279.4 5.9 1.8e-83 279.2 5.9 1.0 1 0 0 1 1 1 1 Clc-like Claudin_2 PF13903.6 CDJ92939.1 - 3.7e-05 23.6 8.0 0.00012 21.9 8.1 1.9 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 CDJ92939.1 - 0.012 15.5 0.1 0.012 15.5 0.1 2.8 2 1 1 3 3 3 0 Tight junction protein, Claudin-like Adeno_E3B PF03376.14 CDJ92939.1 - 0.22 11.8 0.1 0.22 11.8 0.1 2.8 3 0 0 3 3 3 0 Adenovirus E3B protein SUR7 PF06687.12 CDJ92939.1 - 1.3 8.6 16.3 13 5.3 16.1 2.4 1 1 1 2 2 2 0 SUR7/PalI family EF-hand_1 PF00036.32 CDJ92940.1 - 1.6e-20 71.0 0.5 1.7e-09 36.5 0.1 2.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDJ92940.1 - 1.9e-18 66.6 0.3 2.3e-18 66.4 0.3 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CDJ92940.1 - 4.5e-16 58.4 1.5 3.7e-13 49.1 0.2 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ92940.1 - 5.7e-16 57.0 0.3 1.1e-07 31.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDJ92940.1 - 1.8e-14 52.5 0.1 6.8e-08 31.7 0.0 2.2 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 CDJ92940.1 - 1.7e-05 25.1 0.0 2e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CDJ92940.1 - 0.00017 21.5 0.2 0.001 19.0 0.2 1.8 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 CDJ92940.1 - 0.0055 16.9 0.3 0.046 13.9 0.3 2.0 1 1 1 2 2 2 2 Dockerin type I domain EF-hand_9 PF14658.6 CDJ92940.1 - 0.0059 16.9 0.1 0.0075 16.6 0.1 1.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_11 PF08976.11 CDJ92940.1 - 0.0097 16.8 0.0 0.01 16.7 0.0 1.0 1 0 0 1 1 1 1 EF-hand domain UPF0154 PF03672.13 CDJ92940.1 - 0.033 14.2 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Caleosin PF05042.13 CDJ92940.1 - 0.065 13.2 0.2 6.9 6.6 0.0 2.0 1 1 1 2 2 2 0 Caleosin related protein zf-C2H2_4 PF13894.6 CDJ92942.1 - 1e-09 38.4 29.1 0.014 16.2 0.1 6.2 6 0 0 6 6 5 4 C2H2-type zinc finger zf-C2H2 PF00096.26 CDJ92942.1 - 2.9e-09 36.8 19.0 0.042 14.3 0.1 5.6 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 CDJ92942.1 - 0.0016 19.1 13.8 0.0043 17.7 0.2 3.7 1 1 1 3 3 3 1 Zinc finger C2H2-type, 3 repeats Elf1 PF05129.13 CDJ92942.1 - 0.01 15.9 6.2 0.18 11.8 0.2 2.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf_C2H2_ZHX PF18387.1 CDJ92942.1 - 0.16 11.6 7.9 7.2 6.3 0.1 4.0 2 2 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain SIR2 PF02146.17 CDJ92942.1 - 0.2 11.6 2.3 5 7.0 0.2 2.7 2 1 0 2 2 2 0 Sir2 family zf-C2HE PF16278.5 CDJ92942.1 - 0.38 11.2 14.4 3.6 8.1 0.6 4.1 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger DUF2256 PF10013.9 CDJ92942.1 - 0.4 10.8 12.5 0.2 11.8 5.0 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Nudix_N_2 PF14803.6 CDJ92942.1 - 0.48 10.4 6.7 6 6.9 0.1 3.7 3 0 0 3 3 3 0 Nudix N-terminal zf-C2H2_jaz PF12171.8 CDJ92942.1 - 0.55 10.6 10.3 3.4 8.1 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding YhfH PF14149.6 CDJ92942.1 - 0.82 9.7 4.3 33 4.6 0.1 3.6 3 0 0 3 3 3 0 YhfH-like protein OrfB_Zn_ribbon PF07282.11 CDJ92942.1 - 1.2 9.1 9.4 29 4.7 2.7 4.1 2 1 2 4 4 4 0 Putative transposase DNA-binding domain C1_1 PF00130.22 CDJ92942.1 - 1.3 8.9 16.2 0.72 9.8 1.3 3.5 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_11 PF16622.5 CDJ92942.1 - 1.6 8.6 22.2 3.6 7.4 0.1 5.6 5 1 1 6 6 6 0 zinc-finger C2H2-type ADK_lid PF05191.14 CDJ92942.1 - 2.7 8.1 7.0 0.5 10.4 0.2 3.2 3 2 0 3 3 2 0 Adenylate kinase, active site lid zf-C2H2_3 PF13878.6 CDJ92942.1 - 3.5 7.5 8.9 6.1 6.8 1.4 4.0 2 1 1 3 3 3 0 zinc-finger of acetyl-transferase ESCO DNA_RNApol_7kD PF03604.13 CDJ92942.1 - 5.9 6.7 6.8 7.1 6.4 0.2 3.6 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_5 PF13719.6 CDJ92942.1 - 8.6 6.2 11.0 1.2 9.0 3.4 2.9 2 1 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 CDJ92942.1 - 8.9 6.3 14.0 2 8.4 0.3 4.6 5 0 0 5 5 5 0 zinc-ribbon domain ubiquitin PF00240.23 CDJ92943.1 - 3.6e-09 36.2 0.0 4e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family DPPIV_N PF00930.21 CDJ92944.1 - 2.1e-49 168.2 5.8 2.6e-49 167.9 5.8 1.0 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region FBA PF04300.13 CDJ92944.1 - 0.016 14.9 0.0 0.032 13.9 0.0 1.6 1 1 0 1 1 1 0 F-box associated region FidL_like PF15941.5 CDJ92944.1 - 0.45 11.0 3.7 19 5.8 0.1 2.8 2 1 0 2 2 2 0 FidL-like putative membrane protein Collagen PF01391.18 CDJ92945.1 - 6.7e-25 86.6 88.7 0.00023 20.9 7.5 4.2 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ92945.1 - 4.4e-10 39.4 1.1 6e-10 39.0 1.1 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain TTR-52 PF01060.23 CDJ92946.1 - 2e-20 73.3 0.0 2.5e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Transthyretin-like family DUF870 PF05912.11 CDJ92946.1 - 0.0095 15.9 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Caenorhabditis elegans protein of unknown function (DUF870) Mito_carr PF00153.27 CDJ92947.1 - 1.1e-19 70.2 0.3 5.4e-09 35.9 0.1 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein gag-asp_proteas PF13975.6 CDJ92949.1 - 7.4e-05 23.2 0.0 0.00025 21.5 0.0 1.9 1 1 1 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ92949.1 - 8.1e-05 23.2 0.0 0.00039 21.0 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 CDJ92949.1 - 0.0047 17.2 0.0 0.021 15.1 0.0 2.0 1 1 1 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CDJ92950.1 - 0.00038 21.0 0.0 0.00087 19.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease CRS1_YhbY PF01985.21 CDJ92950.1 - 0.016 15.3 0.2 3.1 8.0 0.3 2.4 1 1 1 2 2 2 0 CRS1 / YhbY (CRM) domain DUF371 PF04027.13 CDJ92950.1 - 0.048 13.6 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF371) Asp_protease_2 PF13650.6 CDJ92950.1 - 0.12 13.1 0.0 0.29 11.8 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease VWA PF00092.28 CDJ92951.1 - 1.3e-12 48.3 0.1 1.8e-12 47.9 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CDJ92951.1 - 0.00014 22.5 0.2 0.00031 21.4 0.1 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain HTH_48 PF17906.1 CDJ92952.1 - 0.0034 17.5 0.0 0.012 15.8 0.0 1.8 2 0 0 2 2 2 1 HTH domain in Mos1 transposase UDPGT PF00201.18 CDJ92953.1 - 1.7e-06 27.2 0.0 1.8e-06 27.0 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ92953.1 - 7.3e-05 22.8 0.0 7.9e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Shisa PF13908.6 CDJ92955.1 - 8.6e-05 22.9 0.1 0.00012 22.3 0.1 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TMIE PF16038.5 CDJ92955.1 - 0.0019 18.0 1.1 0.0044 16.8 1.1 1.6 1 0 0 1 1 1 1 TMIE protein Herpes_gE PF02480.16 CDJ92955.1 - 0.0062 15.3 0.0 0.0078 15.0 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.6 CDJ92955.1 - 0.0095 15.9 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family DAG1 PF05454.11 CDJ92955.1 - 0.011 15.1 0.2 0.015 14.7 0.2 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) FtsX PF02687.21 CDJ92955.1 - 0.013 16.0 0.1 0.019 15.5 0.1 1.2 1 0 0 1 1 1 0 FtsX-like permease family MLANA PF14991.6 CDJ92955.1 - 0.018 15.3 0.5 0.028 14.7 0.5 1.3 1 0 0 1 1 1 0 Protein melan-A EphA2_TM PF14575.6 CDJ92955.1 - 0.034 15.0 0.1 0.063 14.2 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5385 PF17359.2 CDJ92955.1 - 0.06 12.9 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF4446 PF14584.6 CDJ92955.1 - 0.077 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) TMEM52 PF14979.6 CDJ92955.1 - 0.082 12.8 2.1 0.15 12.0 2.1 1.4 1 0 0 1 1 1 0 Transmembrane 52 Orthopox_A36R PF05950.11 CDJ92955.1 - 0.087 13.0 0.5 0.16 12.1 0.5 1.5 1 0 0 1 1 1 0 Orthopoxvirus A36R protein DUF4834 PF16118.5 CDJ92955.1 - 0.12 13.4 0.0 0.18 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF5401 PF17380.2 CDJ92957.1 - 2.1e-32 112.1 40.2 3.1e-32 111.5 40.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5401) CBM_14 PF01607.24 CDJ92957.1 - 0.02 15.1 0.1 0.039 14.1 0.1 1.4 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain Lipase_2 PF01674.18 CDJ92958.1 - 0.083 12.4 2.5 0.17 11.4 2.5 1.6 1 0 0 1 1 1 0 Lipase (class 2) bZIP_2 PF07716.15 CDJ92959.1 - 4.7e-11 42.6 8.4 6.9e-11 42.1 8.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CDJ92959.1 - 8e-08 32.3 9.8 1.1e-07 31.8 9.8 1.2 1 0 0 1 1 1 1 bZIP transcription factor HALZ PF02183.18 CDJ92959.1 - 0.0017 18.5 0.3 0.0017 18.5 0.3 1.8 2 0 0 2 2 2 1 Homeobox associated leucine zipper RasGAP_C PF03836.15 CDJ92959.1 - 0.0019 18.3 0.7 0.0031 17.6 0.7 1.4 1 0 0 1 1 1 1 RasGAP C-terminus bZIP_Maf PF03131.17 CDJ92959.1 - 0.0031 18.0 5.4 0.0047 17.4 5.4 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor Prp19 PF08606.11 CDJ92959.1 - 0.021 14.8 0.5 0.036 14.0 0.5 1.3 1 0 0 1 1 1 0 Prp19/Pso4-like DivIC PF04977.15 CDJ92959.1 - 0.049 13.4 2.2 0.098 12.4 2.1 1.6 1 1 0 1 1 1 0 Septum formation initiator DUF4407 PF14362.6 CDJ92959.1 - 0.1 11.9 0.2 0.13 11.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HisKA_3 PF07730.13 CDJ92959.1 - 0.14 12.7 1.6 0.2 12.2 1.6 1.3 1 0 0 1 1 1 0 Histidine kinase FAM76 PF16046.5 CDJ92959.1 - 0.16 11.3 4.5 0.21 10.9 4.5 1.1 1 0 0 1 1 1 0 FAM76 protein bZIP_2 PF07716.15 CDJ92960.1 - 3.6e-12 46.2 15.2 6.3e-12 45.4 15.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CDJ92960.1 - 1.1e-09 38.2 14.0 1.7e-09 37.6 14.0 1.2 1 0 0 1 1 1 1 bZIP transcription factor TolA_bind_tri PF16331.5 CDJ92960.1 - 0.004 17.2 3.9 0.0061 16.6 3.9 1.3 1 0 0 1 1 1 1 TolA binding protein trimerisation SR-25 PF10500.9 CDJ92960.1 - 0.011 15.4 9.2 0.014 15.1 9.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Fungal_TACC PF12709.7 CDJ92960.1 - 0.027 14.9 3.5 0.037 14.5 2.9 1.5 1 1 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins WDCP PF15390.6 CDJ92960.1 - 0.028 12.8 2.4 0.031 12.7 2.4 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family bZIP_Maf PF03131.17 CDJ92960.1 - 0.029 14.9 12.4 0.039 14.5 12.0 1.4 1 1 0 1 1 1 0 bZIP Maf transcription factor DivIC PF04977.15 CDJ92960.1 - 0.065 13.0 6.7 0.041 13.7 4.8 1.6 1 1 0 1 1 1 0 Septum formation initiator RNA_pol_Rpc4 PF05132.14 CDJ92960.1 - 0.068 13.6 0.4 0.075 13.5 0.4 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Dsh_C PF12316.8 CDJ92960.1 - 0.58 10.5 11.1 0.84 10.0 11.1 1.3 1 1 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF4407 PF14362.6 CDJ92960.1 - 1.8 7.8 4.8 2.2 7.5 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 CDJ92960.1 - 7 5.3 5.2 7.7 5.2 5.2 1.1 1 0 0 1 1 1 0 Presenilin Zona_pellucida PF00100.23 CDJ92963.1 - 6.2e-18 65.5 0.7 8.3e-12 45.4 0.1 2.2 2 0 0 2 2 2 2 Zona pellucida-like domain Methyltransf_21 PF05050.12 CDJ92964.1 - 5.9e-15 55.7 0.0 7.3e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase FkbM domain Ion_trans_2 PF07885.16 CDJ92965.1 - 7.1e-23 80.4 17.1 4.4e-13 49.0 0.4 3.2 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CDJ92965.1 - 0.00061 19.1 11.7 0.016 14.4 0.5 2.3 1 1 1 2 2 2 2 Ion transport protein TssO PF17561.2 CDJ92965.1 - 0.003 17.7 0.1 0.003 17.7 0.1 2.2 2 0 0 2 2 2 1 Type VI secretion system, TssO PP2C_C PF07830.13 CDJ92965.1 - 0.33 11.4 1.3 4.7 7.7 0.3 2.8 3 0 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain DUF3671 PF12420.8 CDJ92965.1 - 0.41 10.7 8.6 0.13 12.3 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function CX PF01705.19 CDJ92966.1 - 1.1e-16 61.1 6.8 1.6e-16 60.6 6.8 1.2 1 0 0 1 1 1 1 CX module DUF4688 PF15752.5 CDJ92966.1 - 0.22 10.7 0.4 0.31 10.2 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4688) DUF148 PF02520.17 CDJ92969.1 - 1.1e-13 51.2 1.6 1.6e-13 50.7 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF148 Keratin_2_head PF16208.5 CDJ92969.1 - 0.016 15.4 33.5 0.016 15.4 19.8 2.2 2 0 0 2 2 2 0 Keratin type II head Y_phosphatase PF00102.27 CDJ92970.1 - 1.6e-29 103.1 0.0 7.7e-29 100.9 0.0 1.8 1 1 1 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CDJ92970.1 - 0.00012 22.1 0.1 0.00017 21.6 0.1 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 CDJ92970.1 - 0.00013 21.6 0.1 0.00025 20.7 0.1 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CDJ92970.1 - 0.00027 20.7 0.6 0.00057 19.7 0.3 1.7 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CDJ92970.1 - 0.093 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate KH_1 PF00013.29 CDJ92971.1 - 5.8e-26 90.1 4.8 1.4e-14 53.7 0.4 2.4 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 CDJ92971.1 - 9.1e-11 41.4 2.8 0.00014 21.6 0.3 2.4 1 1 0 2 2 2 2 KH domain KH_4 PF13083.6 CDJ92971.1 - 6.5e-07 29.1 0.8 0.028 14.3 0.1 2.5 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 CDJ92971.1 - 0.00014 21.8 1.3 0.36 10.9 0.1 2.8 3 0 0 3 3 3 2 NusA-like KH domain Sybindin PF04099.12 CDJ92973.1 - 8.9e-51 171.6 0.1 1.2e-50 171.2 0.1 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 CDJ92973.1 - 3.4e-08 33.7 0.0 6.1e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF2096 PF09869.9 CDJ92973.1 - 0.15 12.1 0.6 0.25 11.4 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) Trp_dioxygenase PF03301.13 CDJ92974.1 - 1.8e-153 511.0 3.6 2.1e-153 510.8 3.6 1.0 1 0 0 1 1 1 1 Tryptophan 2,3-dioxygenase IPK PF03770.16 CDJ92976.1 - 1.8e-35 122.6 0.1 5e-35 121.2 0.1 1.7 1 1 0 1 1 1 1 Inositol polyphosphate kinase DENN PF02141.21 CDJ92977.1 - 1.4e-24 87.1 6.0 2.4e-24 86.3 6.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain PDZ PF00595.24 CDJ92979.1 - 8.8e-17 61.2 0.2 1.8e-16 60.2 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDJ92979.1 - 1.2e-07 31.4 0.1 2.3e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ92979.1 - 0.00048 20.4 0.0 0.0013 19.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain APG6_N PF17675.1 CDJ92979.1 - 0.014 16.0 7.4 0.014 16.0 7.4 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region ERM PF00769.19 CDJ92979.1 - 0.06 13.2 7.5 0.098 12.5 7.5 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TMF_TATA_bd PF12325.8 CDJ92979.1 - 0.066 13.4 6.8 0.029 14.6 3.0 2.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding UPF0242 PF06785.11 CDJ92979.1 - 0.07 13.2 4.0 0.16 12.1 4.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4140 PF13600.6 CDJ92979.1 - 0.096 13.1 0.9 0.25 11.8 0.3 2.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Mod_r PF07200.13 CDJ92979.1 - 0.15 12.1 7.6 0.21 11.7 6.8 1.6 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Ufd2P_core PF10408.9 CDJ92979.1 - 0.31 9.6 5.4 0.48 9.0 5.4 1.2 1 0 0 1 1 1 0 Ubiquitin elongating factor core CENP-H PF05837.12 CDJ92979.1 - 0.67 10.4 8.2 0.15 12.4 4.3 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF2730 PF10805.8 CDJ92979.1 - 0.76 9.9 3.3 2.2 8.4 1.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) SOGA PF11365.8 CDJ92979.1 - 0.79 10.9 6.9 0.36 12.0 3.4 2.2 2 0 0 2 2 2 0 Protein SOGA Cnn_1N PF07989.11 CDJ92979.1 - 0.87 9.8 4.1 6.8 6.9 1.3 3.1 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 DUF1664 PF07889.12 CDJ92979.1 - 0.88 9.6 5.0 0.81 9.7 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 CDJ92979.1 - 1.2 9.2 10.1 0.53 10.3 5.4 2.2 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YlqD PF11068.8 CDJ92979.1 - 8.8 6.7 8.7 4.1 7.8 5.7 1.9 1 1 2 3 3 3 0 YlqD protein PDZ PF00595.24 CDJ92980.1 - 7.5e-08 32.6 0.2 9.9e-07 29.0 0.1 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 CDJ92980.1 - 1.6e-06 27.9 0.1 4.5e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 CDJ92980.1 - 0.00011 22.4 0.0 0.00022 21.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 CDJ92980.1 - 0.083 12.9 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain PDZ_4 PF17816.1 CDJ92980.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 CDJ92981.1 - 3.2e-14 53.0 1.1 2.6e-06 27.7 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CDJ92981.1 - 2.7e-13 49.5 0.9 4.3e-06 26.5 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CDJ92981.1 - 6.7e-12 45.6 0.3 0.00018 21.8 0.1 2.5 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 CDJ92981.1 - 4.2e-06 26.6 0.1 0.083 12.9 0.0 2.4 2 0 0 2 2 2 2 Tricorn protease PDZ domain PDZ_4 PF17816.1 CDJ92981.1 - 6.8e-06 26.5 0.1 0.11 12.9 0.0 2.3 2 0 0 2 2 2 2 PDZ domain Leo1 PF04004.13 CDJ92981.1 - 0.047 13.5 0.0 5.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Leo1-like protein FAM91_N PF14647.6 CDJ92982.1 - 1.5e-129 431.8 1.2 2.1e-129 431.2 1.2 1.2 1 0 0 1 1 1 1 FAM91 N-terminus FAM91_C PF14648.6 CDJ92982.1 - 2.8e-116 388.9 0.0 4.1e-116 388.3 0.0 1.2 1 0 0 1 1 1 1 FAM91 C-terminus zf-H2C2_2 PF13465.6 CDJ92982.1 - 1.3e-15 57.0 21.6 5.8e-07 29.7 1.6 4.9 5 0 0 5 5 5 3 Zinc-finger double domain BTB PF00651.31 CDJ92982.1 - 2.8e-12 46.8 0.3 7.8e-08 32.5 0.1 2.5 2 0 0 2 2 2 2 BTB/POZ domain zf-H2C2_5 PF13909.6 CDJ92982.1 - 3.6e-12 45.8 14.0 6.7e-07 29.0 2.1 3.7 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 CDJ92982.1 - 5.3e-11 42.3 19.7 1.6e-06 28.2 1.5 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ92982.1 - 9.4e-08 32.3 15.8 0.00093 19.8 1.2 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-Di19 PF05605.12 CDJ92982.1 - 0.00049 20.3 5.3 0.00049 20.3 5.3 2.6 1 1 2 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.13 CDJ92982.1 - 2.2 8.4 10.7 0.2 11.7 3.3 2.7 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-C2H2_2 PF12756.7 CDJ92982.1 - 4.7 7.6 10.0 12 6.3 0.5 3.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 CDJ92982.1 - 5.5 7.2 6.3 2 8.6 1.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain PyrI_C PF02748.15 CDJ92982.1 - 7.6 6.5 8.9 3.7 7.5 2.2 2.7 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain EF-hand_1 PF00036.32 CDJ92983.1 - 8.7e-18 62.5 3.5 2.4e-07 29.8 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CDJ92983.1 - 3.4e-16 57.7 1.5 5.6e-05 22.8 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 CDJ92983.1 - 1.7e-14 54.0 4.8 1.2e-09 38.5 1.8 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ92983.1 - 6.3e-12 45.2 2.1 1.1e-07 31.6 0.3 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ92983.1 - 3e-09 35.9 2.1 0.00016 21.0 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 CDJ92983.1 - 7.2e-06 26.2 0.1 8.3e-05 22.8 0.0 2.3 2 1 1 3 3 3 1 EF-hand domain EF-hand_4 PF12763.7 CDJ92983.1 - 0.00016 21.6 0.2 0.00022 21.1 0.2 1.2 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand GatB_Yqey PF02637.18 CDJ92983.1 - 0.0066 16.3 0.1 0.011 15.7 0.1 1.3 1 0 0 1 1 1 1 GatB domain Endotoxin_C2 PF18449.1 CDJ92983.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Delta endotoxin DUF4417 PF14386.6 CDJ92984.1 - 0.086 12.4 0.3 0.14 11.8 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4417) TMEM214 PF10151.9 CDJ92984.1 - 7.4 4.9 9.6 10 4.4 9.6 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator ABC2_membrane PF01061.24 CDJ92985.1 - 4.6e-33 114.4 20.8 4.6e-33 114.4 20.8 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 CDJ92985.1 - 6.3e-20 72.1 0.0 9.5e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 CDJ92985.1 - 0.0013 19.1 0.1 0.0023 18.4 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 CDJ92985.1 - 0.002 18.0 0.4 0.73 9.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CDJ92985.1 - 0.0024 17.8 0.1 0.0048 16.8 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 CDJ92985.1 - 0.0037 16.9 0.1 0.0068 16.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDJ92985.1 - 0.0054 17.0 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 CDJ92985.1 - 0.029 13.9 0.2 0.061 12.9 0.2 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CDJ92985.1 - 0.063 13.4 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 CDJ92985.1 - 0.091 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_29 PF13555.6 CDJ92985.1 - 0.13 12.1 0.2 0.28 11.0 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CDJ92985.1 - 0.14 12.2 0.3 0.28 11.3 0.3 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 CDJ92985.1 - 0.15 12.3 0.1 0.39 10.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CDJ92985.1 - 0.18 11.0 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Roc PF08477.13 CDJ92985.1 - 0.2 11.9 0.0 0.39 11.0 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 CDJ92985.1 - 0.21 11.3 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DHHC PF01529.20 CDJ92986.1 - 3.1e-06 27.3 4.5 3.1e-06 27.3 4.5 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Cyclin_N PF00134.23 CDJ92988.1 - 2.2e-11 43.6 0.4 5.1e-11 42.4 0.2 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Afi1 PF07792.12 CDJ92988.1 - 0.76 10.3 2.7 1.7 9.2 2.7 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2828 PF11443.8 CDJ92988.1 - 1.4 6.9 5.4 1.9 6.5 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CDC45 PF02724.14 CDJ92988.1 - 6.2 5.0 13.2 9.2 4.4 13.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CDJ92988.1 - 6.8 5.3 8.6 11 4.6 8.6 1.3 1 0 0 1 1 1 0 Presenilin DUF4551 PF15087.6 CDJ92988.1 - 8.8 5.0 8.2 15 4.2 8.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) 7tm_1 PF00001.21 CDJ92989.1 - 9.4e-50 169.4 11.0 1.1e-49 169.1 11.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ92989.1 - 1.2e-06 28.1 4.1 1.2e-06 28.1 4.1 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 CDJ92989.1 - 1.3e-05 25.0 7.3 1.3e-05 25.0 7.3 2.7 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 CDJ92989.1 - 2e-05 24.0 12.8 4.4e-05 22.9 12.8 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw TAS2R PF05296.13 CDJ92989.1 - 0.00031 19.9 2.1 0.00031 19.9 2.1 2.0 2 0 0 2 2 2 1 Taste receptor protein (TAS2R) 7tm_4 PF13853.6 CDJ92989.1 - 0.0031 17.3 9.2 0.057 13.1 3.1 2.4 1 1 1 2 2 2 2 Olfactory receptor WTF PF03303.13 CDJ92990.1 - 0.003 17.3 0.6 0.0036 17.1 0.6 1.0 1 0 0 1 1 1 1 WTF protein DUF2575 PF10837.8 CDJ92990.1 - 0.091 13.1 1.2 0.11 12.8 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) Lactamase_B PF00753.27 CDJ92991.1 - 9e-20 71.5 0.4 4.8e-19 69.1 0.4 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 CDJ92991.1 - 1.9e-08 34.1 0.0 3.7e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 CDJ92991.1 - 0.00045 19.8 0.1 0.00081 19.0 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_transf_20 PF00982.21 CDJ92993.1 - 3.8e-75 253.4 0.0 2.3e-73 247.5 0.0 2.5 1 1 0 1 1 1 1 Glycosyltransferase family 20 T6PP_N PF18572.1 CDJ92993.1 - 3.4e-34 116.7 0.6 1.1e-33 115.1 0.6 1.9 1 0 0 1 1 1 1 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Hydrolase_3 PF08282.12 CDJ92993.1 - 0.042 13.6 0.3 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CDJ92993.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase MFS_1 PF07690.16 CDJ92994.1 - 4.2e-49 167.4 26.4 4.2e-49 167.4 26.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily EF-hand_6 PF13405.6 CDJ92995.1 - 4.9e-12 44.7 2.4 5.5e-06 25.9 0.3 3.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 CDJ92995.1 - 1.2e-10 41.6 0.1 0.0002 21.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CDJ92995.1 - 3.2e-08 32.5 10.4 3e-05 23.2 1.4 3.9 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 CDJ92995.1 - 9.7e-06 25.3 1.8 0.015 15.1 0.3 3.0 2 1 1 3 3 3 3 EF-hand domain pair UPF0154 PF03672.13 CDJ92995.1 - 3.9e-05 23.6 0.3 0.006 16.6 0.1 2.5 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0154) EF-hand_5 PF13202.6 CDJ92995.1 - 0.0014 18.0 3.0 0.0026 17.2 1.4 2.3 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 CDJ92995.1 - 0.0061 16.9 0.6 0.015 15.6 0.4 1.7 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CDJ92995.1 - 0.0078 16.5 0.0 1.2 9.5 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain DUF2666 PF10869.8 CDJ92995.1 - 0.012 15.9 1.7 2.6 8.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) SurA_N_2 PF13623.6 CDJ92995.1 - 0.023 14.6 0.2 0.27 11.1 0.1 2.2 2 1 0 2 2 2 0 SurA N-terminal domain EF-hand_7 PF13499.6 CDJ92996.1 - 1.3e-11 44.8 0.2 1.3e-05 25.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ92996.1 - 4.4e-11 41.8 2.1 4.5e-05 23.0 0.5 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CDJ92996.1 - 9.5e-07 27.9 7.8 0.00016 21.0 1.2 3.5 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 CDJ92996.1 - 1.4e-05 24.9 1.6 0.012 15.5 0.1 2.8 2 1 1 3 3 3 3 EF-hand domain pair UPF0154 PF03672.13 CDJ92996.1 - 0.00034 20.6 0.3 0.035 14.1 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) EF-hand_5 PF13202.6 CDJ92996.1 - 0.0021 17.5 5.5 0.0091 15.5 1.3 2.6 2 0 0 2 2 2 1 EF hand DUF2666 PF10869.8 CDJ92996.1 - 0.017 15.3 1.1 1.5 9.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) SPARC_Ca_bdg PF10591.9 CDJ92996.1 - 0.023 15.0 0.5 0.058 13.7 0.2 1.8 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CDJ92996.1 - 0.024 15.0 0.0 2.2 8.7 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain N_BRCA1_IG PF16158.5 CDJ92997.1 - 1e-29 103.3 0.1 1.7e-29 102.5 0.1 1.4 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene UBA_4 PF14555.6 CDJ92997.1 - 9.8e-13 47.7 0.0 1.6e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain CARDB PF07705.11 CDJ92997.1 - 0.2 11.9 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 CARDB Beta_elim_lyase PF01212.21 CDJ92999.1 - 3.8e-101 338.2 2.4 4.7e-101 337.9 2.4 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 CDJ92999.1 - 3.8e-13 49.3 0.0 4.7e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CDJ92999.1 - 7.1e-10 38.7 0.1 1.3e-08 34.6 0.0 2.1 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 CDJ92999.1 - 1.1e-06 27.5 0.0 1.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 CDJ92999.1 - 0.00016 20.6 0.0 0.00085 18.2 0.0 2.0 2 0 0 2 2 2 1 Orn/Lys/Arg decarboxylase, major domain PhoU PF01895.19 CDJ93000.1 - 0.0055 17.1 1.9 0.017 15.6 1.8 1.7 1 1 1 2 2 2 1 PhoU domain HTH_24 PF13412.6 CDJ93000.1 - 0.87 9.2 0.1 0.87 9.2 0.1 2.5 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding Srg PF02118.21 CDJ93001.1 - 1.1e-07 31.9 9.9 1.3e-07 31.6 9.9 1.0 1 0 0 1 1 1 1 Srg family chemoreceptor 7tm_1 PF00001.21 CDJ93001.1 - 7.6e-06 25.4 8.1 8.8e-06 25.2 8.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CDJ93001.1 - 6.7e-05 22.6 11.8 0.00012 21.8 11.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Collagen PF01391.18 CDJ93002.1 - 1.1e-22 79.5 68.6 1.1e-09 37.8 29.4 3.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ93002.1 - 0.00017 21.6 0.2 0.00025 21.1 0.2 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Fzo_mitofusin PF04799.13 CDJ93003.1 - 7.5e-48 162.1 1.2 7.5e-48 162.1 1.2 2.5 2 1 0 2 2 2 1 fzo-like conserved region Dynamin_N PF00350.23 CDJ93003.1 - 2.6e-18 66.6 0.1 3.1e-17 63.1 0.0 2.8 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 CDJ93003.1 - 7.2e-06 26.1 1.1 4.5e-05 23.5 0.0 2.9 3 1 0 3 3 3 1 50S ribosome-binding GTPase AIG1 PF04548.16 CDJ93003.1 - 0.0061 15.9 0.1 0.035 13.4 0.0 2.2 2 0 0 2 2 2 1 AIG1 family FtsK_SpoIIIE PF01580.18 CDJ93003.1 - 0.065 12.6 0.0 0.21 10.9 0.0 1.8 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 CDJ93003.1 - 0.26 10.8 1.7 0.34 10.4 0.1 2.0 3 0 0 3 3 3 0 P-loop containing dynein motor region Apolipoprotein PF01442.18 CDJ93003.1 - 3.3 7.6 10.2 0.89 9.4 2.7 2.6 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain MnmE_helical PF12631.7 CDJ93004.1 - 0.023 14.9 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 MnmE helical domain QRPTase_C PF01729.19 CDJ93004.1 - 0.067 13.0 0.6 0.13 12.1 0.6 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain RabGAP-TBC PF00566.18 CDJ93005.1 - 4.9e-42 144.0 0.3 8.4e-42 143.3 0.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH PF00169.29 CDJ93005.1 - 0.00083 19.8 0.0 0.0028 18.1 0.0 1.9 2 0 0 2 2 2 1 PH domain PEX11 PF05648.14 CDJ93005.1 - 0.0017 17.9 0.4 0.0033 16.9 0.4 1.4 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PH_8 PF15409.6 CDJ93005.1 - 0.066 13.5 0.0 0.22 11.8 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain TnpV PF14198.6 CDJ93005.1 - 0.17 11.9 1.7 26 4.8 0.2 3.2 3 0 0 3 3 3 0 Transposon-encoded protein TnpV Fez1 PF06818.15 CDJ93005.1 - 0.24 11.9 16.0 0.52 10.7 10.6 2.6 2 1 0 2 2 2 0 Fez1 RT_RNaseH_2 PF17919.1 CDJ93006.1 - 2.4e-31 107.7 0.1 8e-31 106.0 0.1 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ93006.1 - 2.2e-30 105.0 0.0 8.4e-30 103.2 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ93006.1 - 6.6e-23 81.2 0.0 2.4e-22 79.4 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CDJ93006.1 - 3.8e-19 69.1 0.0 7.2e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ93006.1 - 5.9e-18 64.7 0.0 1.2e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 CDJ93006.1 - 4.2e-09 36.8 0.0 1e-08 35.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ93006.1 - 1.2e-08 35.4 0.0 3.5e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ93006.1 - 1.2e-05 25.6 0.0 3.1e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease rve_3 PF13683.6 CDJ93006.1 - 0.00018 21.3 0.1 0.00053 19.7 0.1 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CDJ93006.1 - 0.025 14.8 0.1 0.072 13.3 0.0 1.9 2 0 0 2 2 1 0 H2C2 zinc finger Inhibitor_I29 PF08246.12 CDJ93006.1 - 1.7 9.2 4.8 30 5.1 0.2 3.4 3 0 0 3 3 3 0 Cathepsin propeptide inhibitor domain (I29) PLAT PF01477.23 CDJ93007.1 - 0.02 15.5 0.3 0.029 14.9 0.3 1.2 1 0 0 1 1 1 0 PLAT/LH2 domain TMEM52 PF14979.6 CDJ93007.1 - 0.028 14.3 3.7 0.074 13.0 0.1 2.2 2 0 0 2 2 2 0 Transmembrane 52 Kelch_1 PF01344.25 CDJ93008.1 - 9.6e-34 114.7 1.1 3.3e-14 52.2 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 CDJ93008.1 - 4.3e-24 84.0 0.0 1.3e-08 34.8 0.0 3.1 2 1 1 3 3 3 3 Kelch motif Kelch_2 PF07646.15 CDJ93008.1 - 6.9e-18 63.8 0.4 3.4e-07 30.0 0.0 3.5 3 1 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 CDJ93008.1 - 4.8e-08 32.9 0.2 0.037 14.0 0.1 3.4 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ93008.1 - 1.6e-07 31.5 0.9 0.0086 16.4 0.1 3.3 2 1 1 3 3 3 2 Galactose oxidase, central domain PQQ PF01011.21 CDJ93008.1 - 1.2e-05 25.0 0.6 0.002 18.0 0.2 2.4 2 0 0 2 2 2 1 PQQ enzyme repeat Kelch_5 PF13854.6 CDJ93008.1 - 3.4e-05 23.7 0.0 0.059 13.4 0.0 2.7 3 0 0 3 3 3 2 Kelch motif Glu_cyclase_2 PF05096.12 CDJ93008.1 - 0.064 12.7 0.0 0.12 11.8 0.0 1.4 1 1 0 1 1 1 0 Glutamine cyclotransferase Sina PF03145.16 CDJ93009.1 - 2.9e-29 102.5 1.8 4.2e-29 101.9 1.8 1.2 1 0 0 1 1 1 1 Seven in absentia protein family Sina PF03145.16 CDJ93011.1 - 1.2e-40 139.7 0.0 1.3e-40 139.5 0.0 1.0 1 0 0 1 1 1 1 Seven in absentia protein family DPM3 PF08285.11 CDJ93013.1 - 8.6e-22 77.2 0.0 1.1e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) CybS PF05328.12 CDJ93013.1 - 0.034 13.8 0.1 0.043 13.5 0.1 1.1 1 0 0 1 1 1 0 CybS, succinate dehydrogenase cytochrome B small subunit DUF5486 PF17588.2 CDJ93013.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5486) SNF2_N PF00176.23 CDJ93014.1 - 4.4e-67 226.3 1.7 7.9e-67 225.4 1.7 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ93014.1 - 6.1e-19 68.4 0.0 1.4e-18 67.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.13 CDJ93014.1 - 4.1e-12 46.3 6.3 4.1e-12 46.3 6.3 3.0 1 1 1 2 2 2 1 HSA ResIII PF04851.15 CDJ93014.1 - 0.00014 21.9 0.0 0.00014 21.9 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF2683 PF10884.8 CDJ93014.1 - 0.13 12.5 1.0 0.5 10.7 1.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) Cauli_AT PF03233.13 CDJ93014.1 - 0.41 10.6 3.0 0.43 10.5 0.0 2.5 2 0 0 2 2 2 0 Aphid transmission protein GTP_EFTU PF00009.27 CDJ93015.1 - 7.2e-55 185.5 0.0 9.3e-55 185.2 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CDJ93015.1 - 5.6e-06 26.7 0.7 1.2e-05 25.6 0.7 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDJ93015.1 - 0.00035 20.6 0.0 0.00057 19.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 CDJ93015.1 - 0.035 13.8 0.1 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain HECT_2 PF09814.9 CDJ93016.1 - 3.9e-22 78.6 1.8 4.3e-22 78.5 1.8 1.2 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding PQ-loop PF04193.14 CDJ93018.1 - 1.3e-39 133.7 11.3 9.3e-20 70.2 3.1 2.4 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 CDJ93018.1 - 0.00093 20.0 3.2 0.011 16.5 0.1 2.8 1 1 1 2 2 2 1 ER lumen protein retaining receptor MtN3_slv PF03083.16 CDJ93018.1 - 0.33 11.0 9.1 4.3 7.5 0.1 2.6 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Exo_endo_phos_2 PF14529.6 CDJ93019.1 - 1.9e-08 34.1 0.0 3.8e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RING_UBOX PF13445.6 CDJ93019.1 - 3.5e-07 30.1 4.4 7.4e-07 29.1 4.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDJ93019.1 - 6.9e-07 29.1 2.9 1.7e-06 27.9 2.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Exo_endo_phos PF03372.23 CDJ93019.1 - 2.4e-05 24.0 0.1 5.1e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-C3HC4_3 PF13920.6 CDJ93019.1 - 9.2e-05 22.2 1.6 0.00022 21.0 1.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ93019.1 - 9.3e-05 22.7 2.5 0.00023 21.4 2.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CDJ93019.1 - 0.00013 21.8 3.3 0.00024 20.9 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ93019.1 - 0.0086 15.9 1.8 0.022 14.6 1.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDJ93019.1 - 0.009 15.9 3.0 0.019 14.8 3.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 CDJ93019.1 - 0.049 13.6 0.3 0.11 12.5 0.3 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.6 CDJ93019.1 - 1.5 9.0 4.8 0.25 11.5 0.8 1.7 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING RVT_1 PF00078.27 CDJ93020.1 - 1.5e-38 132.5 0.1 2.7e-38 131.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hemolysin_N PF12563.8 CDJ93020.1 - 0.059 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Hemolytic toxin N terminal GILT PF03227.16 CDJ93020.1 - 0.079 13.2 0.8 0.24 11.6 0.4 2.0 2 0 0 2 2 2 0 Gamma interferon inducible lysosomal thiol reductase (GILT) zf-B_box PF00643.24 CDJ93021.1 - 1.3e-09 38.1 17.7 2.5e-06 27.5 8.2 3.3 2 1 0 2 2 2 2 B-box zinc finger Rhodanese_C PF12368.8 CDJ93021.1 - 0.2 12.0 14.1 0.23 11.9 4.0 2.8 3 0 0 3 3 3 0 Rhodanase C-terminal Spectrin PF00435.21 CDJ93022.1 - 3.8e-06 27.3 4.4 0.0033 17.9 0.5 2.0 2 0 0 2 2 2 2 Spectrin repeat GvpG PF05120.12 CDJ93022.1 - 0.053 13.5 1.0 0.082 12.9 0.1 1.8 2 1 0 2 2 2 0 Gas vesicle protein G Exo_endo_phos_2 PF14529.6 CDJ93023.1 - 1.1e-06 28.4 0.0 2.1e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ93023.1 - 0.026 14.1 0.0 0.055 13.0 0.0 1.6 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family HRG PF16954.5 CDJ93025.1 - 6.6e-12 45.6 5.6 6.6e-12 45.6 5.6 1.8 2 0 0 2 2 2 1 Haem-transporter, endosomal/lysosomal, haem-responsive gene MnhB PF04039.13 CDJ93025.1 - 0.0046 17.3 1.4 0.0072 16.6 1.1 1.5 1 1 0 1 1 1 1 Domain related to MnhB subunit of Na+/H+ antiporter DUF2207 PF09972.9 CDJ93025.1 - 0.24 10.1 2.7 0.27 10.0 2.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RELT PF12606.8 CDJ93025.1 - 5.8 6.0 6.4 1.6 7.8 2.8 1.9 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 Sec3_C PF09763.9 CDJ93026.1 - 0.14 10.5 0.0 0.17 10.2 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 zf-H2C2_2 PF13465.6 CDJ93027.1 - 8.1e-12 45.0 9.2 2.1e-05 24.7 0.3 4.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDJ93027.1 - 6e-06 26.7 19.4 0.024 15.4 0.8 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 CDJ93027.1 - 6.2e-06 26.4 18.1 0.004 17.5 0.3 4.7 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CDJ93027.1 - 0.00038 20.8 6.2 0.0019 18.6 0.9 4.1 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CDJ93027.1 - 0.026 14.8 12.2 2.7 8.4 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CDJ93027.1 - 0.08 13.0 0.2 0.08 13.0 0.2 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CDJ93027.1 - 0.39 11.0 7.4 0.18 12.1 2.1 2.5 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-Di19 PF05605.12 CDJ93027.1 - 2.2 8.6 10.8 1 9.7 4.2 3.0 2 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF1844 PF08899.11 CDJ93028.1 - 0.11 12.7 0.2 0.32 11.3 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1844) RVT_1 PF00078.27 CDJ93030.1 - 1.6e-20 73.6 0.0 1.4e-12 47.6 0.0 2.0 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) PAP2 PF01569.21 CDJ93031.1 - 5.7e-24 84.4 2.8 1.2e-23 83.4 2.8 1.5 1 0 0 1 1 1 1 PAP2 superfamily Phage_holin_3_3 PF16083.5 CDJ93031.1 - 0.011 15.9 0.5 0.027 14.6 0.5 1.6 1 0 0 1 1 1 0 LydA holin phage, holin superfamily III Colicin_V PF02674.16 CDJ93031.1 - 0.068 13.1 1.7 0.19 11.7 1.7 1.7 1 0 0 1 1 1 0 Colicin V production protein PAP2_C PF14360.6 CDJ93031.1 - 5.2 7.7 13.9 0.086 13.4 1.5 3.2 3 2 0 3 3 3 0 PAP2 superfamily C-terminal BRO1 PF03097.18 CDJ93032.1 - 2e-100 336.3 4.9 2e-100 336.3 4.9 2.1 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CDJ93032.1 - 8.3e-86 287.9 12.7 8.3e-86 287.9 12.7 1.6 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV CDPS PF16715.5 CDJ93032.1 - 0.013 15.1 1.0 0.029 14.0 1.0 1.6 1 0 0 1 1 1 0 Cyclodipeptide synthase Y2_Tnp PF04986.13 CDJ93032.1 - 0.14 12.2 0.0 0.52 10.3 0.0 2.0 1 0 0 1 1 1 0 Putative transposase FlgT_M PF16539.5 CDJ93032.1 - 0.15 12.2 3.2 0.099 12.8 0.7 2.0 2 0 0 2 2 2 0 Flagellar assembly protein T, middle domain HD PF01966.22 CDJ93033.1 - 8.1e-10 39.0 0.0 2e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 HD domain PDEase_I PF00233.19 CDJ93033.1 - 0.044 13.5 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 CDJ93034.1 - 3.4e-10 40.2 0.0 8.5e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 HD domain FliG_C PF01706.16 CDJ93034.1 - 0.0016 18.6 0.5 0.019 15.2 0.1 2.5 2 0 0 2 2 2 1 FliG C-terminal domain PDEase_I PF00233.19 CDJ93034.1 - 0.005 16.6 0.0 0.0077 16.0 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase MutS_V PF00488.21 CDJ93034.1 - 0.21 11.6 0.0 0.43 10.6 0.0 1.4 1 0 0 1 1 1 0 MutS domain V MutS_V PF00488.21 CDJ93035.1 - 2.8e-05 24.2 0.0 0.26 11.3 0.0 2.3 1 1 1 2 2 2 2 MutS domain V DUF1892 PF08987.10 CDJ93035.1 - 0.034 14.3 0.1 7.6 6.8 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1892) Patched PF02460.18 CDJ93036.1 - 2.4e-159 532.0 18.9 1.5e-137 459.9 10.8 2.0 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 CDJ93036.1 - 8.4e-35 119.9 7.7 8.4e-35 119.9 7.7 3.8 4 1 1 5 5 5 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 CDJ93036.1 - 3.1e-06 25.2 4.2 3.1e-06 25.2 4.2 2.0 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family DUF4406 PF14359.6 CDJ93036.1 - 0.12 12.9 0.2 0.79 10.3 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4406) LURAP PF14854.6 CDJ93038.1 - 0.0021 18.0 0.1 0.0041 17.1 0.1 1.4 1 0 0 1 1 1 1 Leucine rich adaptor protein MauJ PF17419.2 CDJ93038.1 - 0.1 12.0 0.1 0.23 10.9 0.0 1.5 2 0 0 2 2 2 0 Methylamine utilization protein MauJ BTB PF00651.31 CDJ93042.1 - 8.7e-26 90.3 0.4 1.5e-24 86.4 0.1 2.3 1 1 1 2 2 2 1 BTB/POZ domain MATH PF00917.26 CDJ93042.1 - 0.022 14.9 0.1 0.045 13.9 0.0 1.5 1 1 0 1 1 1 0 MATH domain NTP_transf_2 PF01909.23 CDJ93043.1 - 1.1e-10 41.7 0.1 2e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 CDJ93043.1 - 7.4e-10 38.9 0.1 2.7e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 Cid1 family poly A polymerase Polbeta PF18765.1 CDJ93043.1 - 0.019 15.0 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Oxidored_q6 PF01058.22 CDJ93044.1 - 6.8e-24 84.2 0.0 9.2e-24 83.8 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit zf-MIZ PF02891.20 CDJ93045.1 - 5.7e-20 70.8 6.8 5.7e-20 70.8 6.8 1.9 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger PINIT PF14324.6 CDJ93045.1 - 2e-18 67.1 0.0 4.4e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 PINIT domain zf-Nse PF11789.8 CDJ93045.1 - 6.5e-09 35.5 1.3 1.3e-08 34.5 1.3 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 CDJ93045.1 - 0.00014 21.5 0.1 0.00025 20.7 0.1 1.4 1 0 0 1 1 1 1 SAP domain PHD PF00628.29 CDJ93045.1 - 0.045 13.6 2.7 0.14 12.1 2.7 1.8 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 CDJ93045.1 - 0.75 10.2 4.9 1.8 9.0 4.9 1.6 1 0 0 1 1 1 0 Ring finger domain DUF5302 PF17227.2 CDJ93046.1 - 0.035 15.1 1.8 2.9 8.9 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5302) YABBY PF04690.13 CDJ93046.1 - 0.081 13.5 2.0 0.14 12.7 2.0 1.4 1 0 0 1 1 1 0 YABBY protein TFIIA PF03153.13 CDJ93046.1 - 0.36 10.8 19.8 0.45 10.4 19.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ric8 PF10165.9 CDJ93047.1 - 4.9e-98 329.1 0.6 5.8e-98 328.9 0.6 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn NDUFV3 PF15880.5 CDJ93048.1 - 6.4e-12 45.3 1.2 1e-11 44.6 1.2 1.4 1 0 0 1 1 1 1 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial Iwr1 PF08574.10 CDJ93049.1 - 8.4e-11 42.7 10.0 8.4e-11 42.7 10.0 2.7 1 1 2 3 3 3 1 Transcription factor Iwr1 TFIIA PF03153.13 CDJ93049.1 - 0.043 13.8 13.0 0.042 13.8 13.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 CDJ93049.1 - 9.2 5.6 11.9 11 5.3 11.9 1.3 1 0 0 1 1 1 0 SDA1 ABC_tran_CTD PF16326.5 CDJ93051.1 - 0.026 14.8 1.9 0.076 13.3 1.9 1.9 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF5446 PF17522.2 CDJ93051.1 - 0.94 9.7 5.8 0.74 10.0 2.5 2.4 2 1 1 3 3 3 0 Family of unknown function (DUF5446) YojJ PF10372.9 CDJ93051.1 - 1.1 9.4 8.0 26 5.0 0.1 3.2 2 1 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus CAP PF00188.26 CDJ93052.1 - 6.4e-09 36.7 1.2 9.7e-09 36.1 1.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ENTH PF01417.20 CDJ93054.1 - 6.8e-07 29.4 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 ENTH domain DHHC PF01529.20 CDJ93055.1 - 1.5e-36 125.4 11.7 1.5e-36 125.4 11.7 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Phage_holin_3_7 PF05449.11 CDJ93055.1 - 0.093 12.8 1.6 0.23 11.5 1.6 1.6 1 0 0 1 1 1 0 Putative 3TM holin, Phage_holin_3 Synapsin_C PF02750.14 CDJ93056.1 - 7.9e-35 120.2 0.1 1.2e-34 119.6 0.1 1.2 1 0 0 1 1 1 1 Synapsin, ATP binding domain ATP-grasp PF02222.22 CDJ93056.1 - 0.062 12.9 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp domain R3H PF01424.22 CDJ93056.1 - 0.15 12.0 0.1 0.45 10.6 0.0 1.8 2 0 0 2 2 2 0 R3H domain An_peroxidase PF03098.15 CDJ93058.1 - 3.3e-161 537.5 0.0 1.6e-159 531.9 0.0 2.0 1 1 0 1 1 1 1 Animal haem peroxidase COPI_C PF06957.11 CDJ93060.1 - 1.1e-158 528.2 0.0 1.4e-158 527.9 0.0 1.0 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus TPR_14 PF13428.6 CDJ93060.1 - 0.0033 18.1 0.1 31 5.7 0.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat GAS PF13851.6 CDJ93061.1 - 0.0091 15.4 7.6 0.014 14.8 7.6 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding 4HB_MCP_1 PF12729.7 CDJ93061.1 - 0.014 15.0 3.9 0.02 14.5 3.9 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction ApoLp-III PF07464.11 CDJ93061.1 - 0.034 14.2 0.6 0.051 13.7 0.6 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF4662 PF15578.6 CDJ93061.1 - 0.078 12.8 0.6 0.1 12.3 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) TMPIT PF07851.13 CDJ93061.1 - 0.11 11.8 2.8 0.19 11.0 2.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein Allexi_40kDa PF05549.11 CDJ93061.1 - 1.1 8.7 5.4 1.4 8.4 3.4 1.8 1 1 1 2 2 2 0 Allexivirus 40kDa protein Spc24 PF08286.11 CDJ93061.1 - 1.2 9.4 7.5 0.42 10.9 1.4 2.7 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 FlxA PF14282.6 CDJ93061.1 - 2.1 8.4 9.9 4.5 7.3 6.7 2.3 1 1 1 2 2 2 0 FlxA-like protein CLZ PF16526.5 CDJ93061.1 - 3.5 8.1 7.7 1.3 9.4 0.7 2.9 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BLOC1_2 PF10046.9 CDJ93061.1 - 3.7 7.9 8.2 0.94 9.8 3.0 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 CDJ93061.1 - 4.1 7.5 7.8 6.4 6.8 2.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Patatin PF01734.22 CDJ93062.1 - 2.5e-10 40.9 0.4 9.1e-10 39.1 0.4 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase RAI16-like PF10257.9 CDJ93063.1 - 2.6e-51 174.6 8.0 4.8e-51 173.7 8.0 1.5 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Sigma54_CBD PF04963.13 CDJ93063.1 - 0.14 12.0 1.2 11 5.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 factor, core binding domain POPLD PF08170.12 CDJ93064.1 - 2.9e-19 69.2 1.3 3.9e-19 68.8 0.0 1.9 2 0 0 2 2 2 1 POPLD (NUC188) domain DUF1459 PF07312.11 CDJ93065.1 - 2.9e-08 33.8 4.3 3.4e-08 33.6 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1459) Exonuc_VII_S PF02609.16 CDJ93067.1 - 0.014 15.4 2.1 0.082 13.0 0.2 2.7 3 0 0 3 3 3 0 Exonuclease VII small subunit BLOC1_2 PF10046.9 CDJ93067.1 - 0.037 14.3 0.1 0.44 10.9 0.0 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_DNA_bd PF12329.8 CDJ93067.1 - 0.13 12.3 1.1 1.1 9.3 0.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Ig_3 PF13927.6 CDJ93068.1 - 1.4e-24 86.5 0.2 5.1e-14 52.6 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 CDJ93068.1 - 1.7e-24 85.7 0.0 4.6e-15 55.5 0.0 3.4 4 0 0 4 4 4 2 Immunoglobulin I-set domain Ig_2 PF13895.6 CDJ93068.1 - 3.3e-17 62.6 0.1 2.3e-07 31.0 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 CDJ93068.1 - 5.9e-17 61.6 0.0 2.7e-10 40.3 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin domain fn3 PF00041.21 CDJ93068.1 - 3.6e-16 59.3 0.5 1.1e-06 28.9 0.1 2.9 3 0 0 3 3 2 2 Fibronectin type III domain V-set PF07686.17 CDJ93068.1 - 4.4e-07 30.0 0.6 0.11 12.7 0.2 4.3 2 2 0 2 2 2 2 Immunoglobulin V-set domain Ig_5 PF16681.5 CDJ93068.1 - 0.00031 21.1 0.0 0.53 10.7 0.0 3.2 2 1 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain BiPBP_C PF06832.12 CDJ93068.1 - 0.00094 19.2 0.0 1.5 8.9 0.0 2.6 2 0 0 2 2 2 2 Penicillin-Binding Protein C-terminus Family Izumo-Ig PF16706.5 CDJ93068.1 - 0.0039 17.2 0.0 2.7 8.1 0.0 2.4 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain C1-set PF07654.15 CDJ93068.1 - 0.0046 17.3 0.3 5.6 7.4 0.0 3.0 3 1 0 3 3 3 2 Immunoglobulin C1-set domain Ig_6 PF18452.1 CDJ93068.1 - 0.011 15.3 0.0 0.97 9.1 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 CDJ93068.1 - 0.014 16.0 0.2 25 5.5 0.0 3.4 3 1 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain ABC_membrane PF00664.23 CDJ93069.1 - 2.8e-57 194.5 15.2 5.5e-57 193.5 15.2 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ93069.1 - 2.9e-32 112.0 0.0 6.2e-32 111.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CDJ93069.1 - 1.7e-08 34.2 1.1 7.2e-07 28.9 1.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDJ93069.1 - 0.00029 21.3 0.2 0.0026 18.2 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CDJ93069.1 - 0.003 17.5 0.0 0.0072 16.3 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 CDJ93069.1 - 0.01 16.1 0.1 4.7 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF1360 PF07098.11 CDJ93069.1 - 0.012 15.6 0.2 8.2 6.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) AAA_30 PF13604.6 CDJ93069.1 - 0.016 15.0 0.0 0.07 12.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CDJ93069.1 - 0.019 14.7 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 CDJ93069.1 - 0.02 14.6 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain VGCC_alpha2 PF08473.11 CDJ93069.1 - 0.08 11.7 0.4 0.23 10.2 0.0 1.8 2 0 0 2 2 2 0 Neuronal voltage-dependent calcium channel alpha 2acd AAA PF00004.29 CDJ93069.1 - 0.088 13.2 0.2 1.5 9.2 0.2 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DNA_pol3_beta PF00712.19 CDJ93069.1 - 0.099 12.8 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain ACR_tran PF00873.19 CDJ93069.1 - 0.38 8.4 6.5 0.046 11.4 1.3 1.9 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family DUF3767 PF12597.8 CDJ93070.1 - 0.12 12.2 2.3 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3767) DUF2189 PF09955.9 CDJ93070.1 - 0.32 11.3 8.7 0.057 13.7 2.2 2.2 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2189) ATP_synt_H PF05493.13 CDJ93070.1 - 0.48 10.9 0.2 0.48 10.9 0.2 3.0 3 1 0 3 3 3 0 ATP synthase subunit H Pkinase PF00069.25 CDJ93071.1 - 5.1e-18 65.4 0.0 5.8e-18 65.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ93071.1 - 6.8e-09 35.4 0.0 1.1e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ93071.1 - 0.0022 18.0 0.0 1.1 9.1 0.0 2.6 3 0 0 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ93071.1 - 0.0055 15.5 0.0 0.0055 15.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 CDJ93071.1 - 0.18 11.4 0.0 20 4.7 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RVT_1 PF00078.27 CDJ93072.1 - 5.2e-18 65.4 0.0 8.2e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_1 PF07690.16 CDJ93073.1 - 5.9e-53 180.0 17.9 8.1e-51 173.0 14.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YtpI PF14007.6 CDJ93073.1 - 0.65 10.2 4.8 1.1 9.5 0.2 3.1 2 1 1 3 3 3 0 YtpI-like protein DUF3311 PF11755.8 CDJ93073.1 - 1.4 9.0 7.0 2 8.4 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3311) Bax1-I PF01027.20 CDJ93074.1 - 1.7e-43 148.9 17.2 1.7e-43 148.9 17.2 1.5 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 Fez1 PF06818.15 CDJ93075.1 - 0.00092 19.7 8.7 0.00092 19.7 8.7 3.0 1 1 2 3 3 3 1 Fez1 TSC22 PF01166.18 CDJ93075.1 - 0.0015 18.8 3.3 0.0015 18.8 3.3 3.6 4 0 0 4 4 3 1 TSC-22/dip/bun family BLOC1_2 PF10046.9 CDJ93075.1 - 0.015 15.6 3.1 0.015 15.6 3.1 4.7 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.11 CDJ93075.1 - 0.049 13.9 38.3 0.056 13.7 22.2 3.2 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF3141 PF11339.8 CDJ93075.1 - 0.15 10.4 2.0 0.21 10.0 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) DUF948 PF06103.11 CDJ93075.1 - 0.17 12.2 8.7 6.4 7.1 0.6 3.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) WD40_alt PF14077.6 CDJ93075.1 - 0.17 11.7 7.4 0.84 9.5 0.5 4.1 4 0 0 4 4 4 0 Alternative WD40 repeat motif DUF4988 PF16378.5 CDJ93075.1 - 0.28 10.8 5.3 1.5 8.5 1.7 2.7 2 0 0 2 2 2 0 Domain of unknown function FapA PF03961.13 CDJ93075.1 - 1.2 7.7 24.2 0.1 11.2 5.4 2.8 1 1 2 3 3 3 0 Flagellar Assembly Protein A YabA PF06156.13 CDJ93075.1 - 1.4 9.6 22.5 0.39 11.4 8.3 3.5 2 1 1 3 3 3 0 Initiation control protein YabA Spc7 PF08317.11 CDJ93075.1 - 1.4 7.7 36.6 2.6 6.8 21.7 2.7 1 1 1 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 CDJ93075.1 - 2.4 7.5 37.0 0.017 14.5 8.6 3.7 2 2 1 3 3 3 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 CDJ93075.1 - 3.1 7.9 32.6 5.1 7.2 5.9 2.6 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus PhoU PF01895.19 CDJ93075.1 - 4.4 7.8 17.9 0.33 11.4 1.1 3.7 3 2 1 4 4 4 0 PhoU domain Cnn_1N PF07989.11 CDJ93075.1 - 5.5 7.2 26.4 2.5 8.3 5.8 4.6 3 1 2 5 5 5 0 Centrosomin N-terminal motif 1 FUSC PF04632.12 CDJ93075.1 - 6.3 5.2 5.0 3.6 6.0 3.0 1.4 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF4407 PF14362.6 CDJ93075.1 - 6.4 6.0 21.9 1.4 8.2 14.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Occludin_ELL PF07303.13 CDJ93075.1 - 6.5 7.5 16.2 0.86 10.4 6.8 3.3 2 1 1 3 3 3 0 Occludin homology domain Fib_alpha PF08702.10 CDJ93075.1 - 6.9 6.8 21.3 12 6.0 12.4 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 CDJ93075.1 - 7.1 6.5 21.4 0.49 10.2 4.7 4.5 4 2 0 4 4 4 0 Septum formation initiator FlaC_arch PF05377.11 CDJ93075.1 - 7.6 7.0 20.9 0.18 12.3 3.8 4.7 3 3 2 5 5 5 0 Flagella accessory protein C (FlaC) ShK PF01549.24 CDJ93077.1 - 0.0087 16.6 4.2 0.0087 16.6 4.2 2.7 2 1 0 2 2 2 2 ShK domain-like zf-Di19 PF05605.12 CDJ93078.1 - 0.0023 18.2 2.8 1.2 9.5 0.3 2.4 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding Collagen PF01391.18 CDJ93079.1 - 5.1e-27 93.4 105.9 5.3e-11 42.1 34.5 4.1 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ93079.1 - 3.1e-21 75.2 0.8 4.6e-21 74.6 0.8 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain COX14 PF14880.6 CDJ93079.1 - 0.61 10.0 4.8 0.93 9.4 4.8 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Collagen PF01391.18 CDJ93080.1 - 2.3e-26 91.3 107.6 1.2e-10 40.9 36.8 3.9 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ93080.1 - 1.3e-16 60.4 0.2 1.6e-16 60.1 0.2 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain COX14 PF14880.6 CDJ93080.1 - 0.44 10.4 4.5 0.13 12.1 1.1 1.7 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Collagen PF01391.18 CDJ93081.1 - 3e-25 87.8 110.8 9e-10 38.2 37.1 4.0 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ93081.1 - 3.9e-20 71.7 0.9 4.9e-20 71.3 0.9 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain COX14 PF14880.6 CDJ93081.1 - 1.1 9.1 3.6 1.7 8.5 3.6 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Nucleoside_tran PF01733.18 CDJ93082.1 - 8.3e-21 74.7 6.1 8.3e-21 74.7 6.1 1.8 2 0 0 2 2 2 1 Nucleoside transporter DUF2079 PF09852.9 CDJ93082.1 - 0.051 12.4 9.2 0.066 12.1 9.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) UQ_con PF00179.26 CDJ93082.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme AMP-binding PF00501.28 CDJ93083.1 - 8.2e-106 354.1 0.0 2.8e-53 181.0 0.1 3.0 2 1 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 CDJ93083.1 - 4.4e-102 342.1 0.0 1.4e-39 136.0 0.0 5.1 4 1 0 4 4 4 4 Condensation domain PP-binding PF00550.25 CDJ93083.1 - 6.1e-32 109.8 0.4 1.1e-10 41.7 0.0 4.4 4 0 0 4 4 4 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 CDJ93083.1 - 1.2e-11 45.4 0.0 2.6e-08 34.7 0.1 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Transferase PF02458.15 CDJ93083.1 - 0.026 13.2 0.0 0.39 9.3 0.0 2.3 2 0 0 2 2 2 0 Transferase family Rep_fac_C PF08542.11 CDJ93083.1 - 0.07 13.5 0.0 0.27 11.7 0.0 2.0 1 0 0 1 1 1 0 Replication factor C C-terminal domain AMP-binding PF00501.28 CDJ93084.1 - 4.1e-50 170.6 0.0 6.8e-50 169.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 CDJ93084.1 - 5.9e-50 170.3 0.0 1.8e-49 168.7 0.0 1.7 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 CDJ93084.1 - 1.7e-07 31.4 0.0 0.0002 21.6 0.0 3.4 3 0 0 3 3 3 2 Phosphopantetheine attachment site S_100 PF01023.19 CDJ93084.1 - 0.22 11.2 0.8 1.2 8.9 0.0 2.6 3 0 0 3 3 3 0 S-100/ICaBP type calcium binding domain Kelch_1 PF01344.25 CDJ93085.1 - 3.6e-14 52.1 0.2 2.1e-06 27.2 0.0 3.5 3 0 0 3 3 3 3 Kelch motif BTB PF00651.31 CDJ93085.1 - 7.7e-07 29.3 0.0 1.1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.6 CDJ93085.1 - 4e-05 23.7 0.0 0.0081 16.4 0.0 3.1 2 1 1 3 3 3 1 Kelch motif Kelch_3 PF13415.6 CDJ93085.1 - 0.0039 17.5 0.4 0.28 11.5 0.2 3.3 3 1 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ93085.1 - 0.066 13.2 0.0 7.5 6.7 0.0 2.7 3 0 0 3 3 3 0 Kelch motif BTB PF00651.31 CDJ93086.1 - 8.2e-31 106.5 0.5 1.2e-28 99.5 0.3 2.3 2 0 0 2 2 2 2 BTB/POZ domain BACK PF07707.15 CDJ93086.1 - 7.8e-14 51.6 0.8 2.8e-07 30.6 0.0 3.2 2 1 1 3 3 3 2 BTB And C-terminal Kelch Kelch_1 PF01344.25 CDJ93086.1 - 2.1e-10 40.0 1.3 0.00027 20.4 0.1 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 CDJ93086.1 - 0.0057 16.9 0.1 0.15 12.4 0.0 2.7 2 1 1 3 3 3 1 Kelch motif CAP PF00188.26 CDJ93087.1 - 8.7e-19 68.6 4.4 1.3e-18 68.1 4.4 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ93087.1 - 0.048 13.9 2.3 0.35 11.2 2.2 2.4 1 1 0 1 1 1 0 Ancylostoma-associated secreted protein related Cyclin_N PF00134.23 CDJ93088.1 - 1.4e-08 34.6 0.0 1.5e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF229 PF02995.17 CDJ93089.1 - 2.7e-67 227.5 1.0 3.2e-67 227.2 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 CDJ93089.1 - 0.00024 20.6 0.0 0.00045 19.7 0.0 1.4 1 1 0 1 1 1 1 Sulfatase DDE_Tnp_ISAZ013 PF07592.11 CDJ93089.1 - 0.034 13.1 0.2 0.071 12.1 0.1 1.6 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain DUF229 PF02995.17 CDJ93091.1 - 1.7e-87 294.2 5.8 2.1e-87 293.8 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 CDJ93091.1 - 0.00057 19.4 0.0 0.00088 18.7 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Evr1_Alr PF04777.13 CDJ93093.1 - 0.076 13.5 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Erv1 / Alr family DUF1449 PF07290.11 CDJ93093.1 - 0.22 11.1 1.5 0.44 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1449) DUF1201 PF06716.11 CDJ93094.1 - 0.13 12.3 0.4 0.13 12.3 0.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1201) ABC_membrane PF00664.23 CDJ93095.1 - 4.9e-55 187.1 17.2 6.6e-55 186.7 17.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ93095.1 - 3.9e-34 118.1 0.0 7.1e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CDJ93095.1 - 2.3e-09 37.0 0.1 1e-06 28.3 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDJ93095.1 - 0.0019 18.6 0.1 0.0075 16.7 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDJ93095.1 - 0.0041 17.4 0.1 0.027 14.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ93095.1 - 0.0085 15.8 0.2 0.097 12.4 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CDJ93095.1 - 0.011 15.4 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 CDJ93095.1 - 0.014 15.8 0.6 1.1 9.7 0.1 2.6 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 CDJ93095.1 - 0.017 14.8 0.0 1.3 8.7 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 CDJ93095.1 - 0.028 14.3 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 CDJ93095.1 - 0.09 13.0 1.1 1.2 9.4 1.1 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 CDJ93095.1 - 0.18 11.5 0.1 11 5.7 0.1 2.5 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system MADF_DNA_bdg PF10545.9 CDJ93096.1 - 0.00031 21.0 0.0 0.00047 20.4 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Mon1 PF03164.14 CDJ93097.1 - 4.2e-65 220.4 4.7 2.9e-34 118.8 0.2 3.0 1 1 1 2 2 2 2 Trafficking protein Mon1 YabA PF06156.13 CDJ93098.1 - 1 10.0 12.8 1.7 9.3 0.1 3.1 3 0 0 3 3 3 0 Initiation control protein YabA Vir_act_alpha_C PF10400.9 CDJ93098.1 - 1.3 9.8 8.0 14 6.5 0.2 3.3 3 0 0 3 3 3 0 Virulence activator alpha C-term Lectin_N PF03954.14 CDJ93098.1 - 2.4 7.9 10.5 4.8 6.9 0.2 3.2 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain DUF2205 PF10224.9 CDJ93098.1 - 2.4 8.2 17.5 0.62 10.1 0.1 4.0 3 1 0 3 3 3 0 Short coiled-coil protein Keratin_2_head PF16208.5 CDJ93099.1 - 7.8 6.6 33.2 9.9 6.3 33.2 1.1 1 0 0 1 1 1 0 Keratin type II head Costars PF14705.6 CDJ93101.1 - 2.7e-30 104.3 0.3 3.2e-30 104.1 0.3 1.1 1 0 0 1 1 1 1 Costars Mab-21 PF03281.14 CDJ93103.1 - 6.9e-85 284.9 0.0 8.8e-85 284.6 0.0 1.1 1 0 0 1 1 1 1 Mab-21 protein Frankia_peptide PF14407.6 CDJ93103.1 - 0.045 13.7 0.1 0.51 10.4 0.0 2.2 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Beach PF02138.18 CDJ93104.1 - 2.1e-122 407.8 0.8 2.7e-122 407.5 0.8 1.1 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 CDJ93104.1 - 7e-16 58.2 0.1 1.5e-15 57.1 0.1 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Hrs_helical PF12210.8 CDJ93105.1 - 0.012 16.1 11.4 0.012 16.1 11.4 4.0 3 1 1 4 4 4 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF802 PF05650.11 CDJ93105.1 - 0.14 12.7 0.1 0.14 12.7 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF802) Actin PF00022.19 CDJ93106.1 - 4.2e-151 503.2 0.0 1.4e-150 501.5 0.0 1.7 1 1 0 1 1 1 1 Actin Actin PF00022.19 CDJ93107.1 - 8.3e-34 116.9 0.0 9.2e-34 116.7 0.0 1.0 1 0 0 1 1 1 1 Actin Rhodanese PF00581.20 CDJ93108.1 - 3.8e-26 91.7 0.0 1.1e-12 48.4 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain CSN8_PSD8_EIF3K PF10075.9 CDJ93109.1 - 3.2e-30 105.0 0.0 1.3e-14 54.4 0.0 3.1 2 1 0 2 2 2 2 CSN8/PSMD8/EIF3K family DUF5466 PF17554.2 CDJ93109.1 - 0.088 13.0 0.1 22 5.3 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5466) RhoGAP PF00620.27 CDJ93111.1 - 1.7e-42 144.8 0.0 4.6e-42 143.4 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 CDJ93111.1 - 3.5e-05 23.6 7.8 8.4e-05 22.4 7.8 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FCH PF00611.23 CDJ93111.1 - 0.00064 20.0 0.1 0.0027 18.0 0.1 2.2 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Prok-RING_1 PF14446.6 CDJ93111.1 - 0.061 13.3 7.7 0.2 11.6 7.7 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.11 CDJ93111.1 - 0.74 10.2 12.9 0.4 11.0 9.7 2.3 2 0 0 2 2 2 0 RING-like domain Aminotran_1_2 PF00155.21 CDJ93112.1 - 1.1e-36 126.8 0.0 1.3e-36 126.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CDJ93112.1 - 0.0023 17.2 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 CDJ93112.1 - 0.15 10.5 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CDJ93113.1 - 1.2e-34 120.0 0.0 1.6e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CDJ93113.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Ribosomal_L9_N PF01281.19 CDJ93114.1 - 0.075 12.6 0.4 0.77 9.4 0.1 2.2 2 0 0 2 2 2 0 Ribosomal protein L9, N-terminal domain Gly_kinase PF02595.15 CDJ93115.1 - 0.36 9.8 4.0 0.39 9.7 4.0 1.1 1 0 0 1 1 1 0 Glycerate kinase family PKcGMP_CC PF16808.5 CDJ93118.1 - 0.0069 16.2 3.1 0.014 15.3 3.1 1.5 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase TMF_DNA_bd PF12329.8 CDJ93118.1 - 0.032 14.2 0.2 0.072 13.1 0.2 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF3158 PF11358.8 CDJ93118.1 - 0.081 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3158) Ank_4 PF13637.6 CDJ93119.1 - 2.3e-28 98.2 3.8 9e-08 32.5 0.0 6.3 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ93119.1 - 3.4e-28 98.1 1.4 5.1e-09 36.6 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ93119.1 - 1.7e-25 88.3 2.5 5.1e-05 23.5 0.0 5.9 5 1 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 CDJ93119.1 - 1.3e-24 83.6 1.6 4.3e-05 23.6 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 CDJ93119.1 - 3.1e-24 84.7 1.8 3.6e-07 30.3 0.0 5.5 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Death PF00531.22 CDJ93119.1 - 8.8e-06 25.8 0.5 1.9e-05 24.7 0.5 1.5 1 0 0 1 1 1 1 Death domain Dynein_light PF01221.18 CDJ93120.1 - 7.5e-05 23.0 0.1 9.2e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 AA_permease PF00324.21 CDJ93121.1 - 3e-67 227.3 27.4 2.2e-48 165.0 5.0 2.1 2 0 0 2 2 2 2 Amino acid permease SLC12 PF03522.15 CDJ93121.1 - 7e-37 127.5 4.2 1.1e-26 93.9 4.9 3.2 1 1 1 2 2 2 2 Solute carrier family 12 AA_permease_2 PF13520.6 CDJ93121.1 - 4.6e-22 78.4 36.7 1.1e-20 73.8 13.7 2.1 2 0 0 2 2 2 2 Amino acid permease DUF5641 PF18701.1 CDJ93122.1 - 3.1e-15 56.1 0.0 6.5e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5641) rve_3 PF13683.6 CDJ93122.1 - 0.00035 20.3 0.6 0.00092 19.0 0.1 2.0 2 0 0 2 2 2 1 Integrase core domain C1_1 PF00130.22 CDJ93124.1 - 1.5e-17 63.2 13.3 2.1e-17 62.7 13.3 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 CDJ93124.1 - 0.059 13.7 5.8 0.17 12.2 6.0 1.7 2 0 0 2 2 2 0 C1 domain DUF4656 PF15551.6 CDJ93124.1 - 0.13 11.7 0.6 0.16 11.5 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4656) Kinesin PF00225.23 CDJ93125.1 - 3.4e-100 335.2 0.1 3.4e-100 335.2 0.1 3.0 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ93125.1 - 1.5e-26 93.1 2.8 6.1e-26 91.2 0.0 2.9 2 0 0 2 2 2 1 Microtubule binding DUF4164 PF13747.6 CDJ93125.1 - 0.0028 17.9 2.2 0.0028 17.9 2.2 8.5 3 3 7 10 10 10 1 Domain of unknown function (DUF4164) Ribonuc_red_lgN PF00317.21 CDJ93125.1 - 0.087 12.8 0.3 25 4.9 2.1 3.0 2 1 0 2 2 2 0 Ribonucleotide reductase, all-alpha domain TPR_MLP1_2 PF07926.12 CDJ93127.1 - 0.02 14.9 2.3 2 8.5 0.2 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein GM_CSF PF01109.17 CDJ93127.1 - 0.073 13.2 0.1 0.28 11.3 0.1 2.0 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor CdvA PF18822.1 CDJ93127.1 - 0.25 11.2 2.1 3.3 7.6 0.9 2.6 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Hexapep PF00132.24 CDJ93128.1 - 1.5e-08 34.0 4.8 0.0023 17.6 1.5 3.7 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CDJ93128.1 - 0.35 10.7 6.9 0.87 9.4 4.3 3.0 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase Neur_chan_LBD PF02931.23 CDJ93129.1 - 1.4e-27 96.5 0.0 2.2e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ93129.1 - 7.5e-15 55.6 2.1 7.5e-15 55.6 2.1 2.4 2 1 2 4 4 4 1 Neurotransmitter-gated ion-channel transmembrane region Kelch_1 PF01344.25 CDJ93131.1 - 5.2e-15 54.8 8.2 5.5e-05 22.7 0.3 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 CDJ93131.1 - 2.9e-09 36.8 1.1 0.0013 18.7 0.0 5.4 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ93131.1 - 3.6e-07 30.0 0.6 5.6e-05 23.0 0.5 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 CDJ93131.1 - 3.7e-06 27.0 0.5 0.00043 20.5 0.1 3.5 3 1 1 4 4 4 1 Kelch motif Kelch_3 PF13415.6 CDJ93131.1 - 7.9e-06 26.0 0.8 1.4 9.3 0.0 5.3 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CDJ93131.1 - 0.0038 17.2 1.9 0.17 11.9 0.1 4.2 6 0 0 6 6 6 1 Kelch motif Pkinase_Tyr PF07714.17 CDJ93132.1 - 1.5e-93 312.8 0.0 1.9e-93 312.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ93132.1 - 1.1e-49 169.2 0.0 1.5e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDJ93132.1 - 4.5e-24 84.4 0.1 8.6e-24 83.4 0.1 1.5 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 CDJ93132.1 - 5.4e-17 61.1 0.1 1.3e-16 59.9 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CDJ93132.1 - 8.6e-14 51.1 0.1 2.7e-13 49.5 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CDJ93132.1 - 2.5e-10 39.9 0.0 7.6e-10 38.3 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Haspin_kinase PF12330.8 CDJ93132.1 - 7e-06 25.2 0.1 1.6e-05 24.0 0.1 1.6 1 1 0 1 1 1 1 Haspin like kinase domain hSH3 PF14603.6 CDJ93132.1 - 0.03 14.8 0.0 0.066 13.6 0.0 1.5 1 0 0 1 1 1 0 Helically-extended SH3 domain Kdo PF06293.14 CDJ93132.1 - 0.049 13.0 0.6 0.094 12.1 0.6 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDJ93132.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like ERO1 PF04137.15 CDJ93133.1 - 3.8e-112 375.0 0.0 4.5e-112 374.8 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Tmemb_14 PF03647.13 CDJ93134.1 - 2.3e-22 79.5 9.9 2.9e-22 79.2 9.9 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C Patatin PF01734.22 CDJ93134.1 - 0.07 13.3 0.5 0.075 13.2 0.5 1.1 1 0 0 1 1 1 0 Patatin-like phospholipase MADF_DNA_bdg PF10545.9 CDJ93135.1 - 9.6e-05 22.6 1.2 0.00093 19.5 0.0 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like MADF_DNA_bdg PF10545.9 CDJ93136.1 - 7.4e-11 42.2 1.5 1.8e-10 41.0 1.5 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 CDJ93136.1 - 1.4e-07 31.8 1.0 3.1e-07 30.7 1.0 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 CDJ93137.1 - 7.7e-28 96.6 5.4 3.6e-14 52.8 0.4 2.7 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 CDJ93137.1 - 2.9e-15 56.4 6.9 9.3e-08 32.4 1.5 2.5 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 CDJ93137.1 - 0.00079 20.4 9.6 0.22 12.6 1.3 3.2 3 1 0 3 3 3 2 Myb/SANT-like DNA-binding domain YlbD_coat PF14071.6 CDJ93137.1 - 0.056 13.7 5.1 2.2 8.5 0.1 2.8 2 1 0 2 2 2 0 Putative coat protein PBECR1 PF18809.1 CDJ93137.1 - 0.14 12.9 0.8 0.86 10.3 0.0 2.5 3 0 0 3 3 3 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 Enkurin PF13864.6 CDJ93137.1 - 0.17 12.3 1.6 5.2 7.6 0.2 2.6 2 0 0 2 2 2 0 Calmodulin-binding UPF0160 PF03690.13 CDJ93137.1 - 0.26 10.9 2.0 7.8 6.0 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0160) MADF_DNA_bdg PF10545.9 CDJ93138.1 - 3.1e-14 53.1 0.7 9.2e-14 51.5 0.7 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 CDJ93138.1 - 5.5e-08 33.1 1.2 1.1e-07 32.1 1.2 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 CDJ93138.1 - 0.074 14.0 3.1 0.41 11.7 2.0 2.6 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain RNA_pol_Rpb2_3 PF04565.16 CDJ93138.1 - 0.077 13.2 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 3 UPF0160 PF03690.13 CDJ93138.1 - 0.41 10.2 1.9 1.3 8.6 0.2 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0160) Laminin_N PF00055.17 CDJ93139.1 - 1.1e-82 277.1 0.7 4.1e-82 275.3 0.0 1.8 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 CDJ93139.1 - 1.4e-07 31.5 12.5 1.4e-07 31.5 12.5 2.5 3 0 0 3 3 3 1 Laminin EGF domain Utp12 PF04003.12 CDJ93140.1 - 2e-15 57.0 2.9 2.8e-15 56.5 2.9 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family UTP15_C PF09384.10 CDJ93140.1 - 0.12 12.1 0.4 0.19 11.4 0.4 1.4 1 0 0 1 1 1 0 UTP15 C terminal DUF5604 PF18300.1 CDJ93141.1 - 0.025 14.5 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5604) EI24 PF07264.11 CDJ93143.1 - 7.5e-05 23.0 0.9 0.00066 20.0 0.0 2.0 1 1 1 2 2 2 1 Etoposide-induced protein 2.4 (EI24) DUF2070 PF09843.9 CDJ93143.1 - 0.013 13.8 8.7 0.017 13.5 8.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Choline_transpo PF04515.12 CDJ93143.1 - 0.03 13.5 9.4 0.19 10.9 9.4 1.9 1 1 0 1 1 1 0 Plasma-membrane choline transporter DUF4728 PF15860.5 CDJ93143.1 - 0.078 13.7 17.6 0.84 10.4 11.8 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4728) Shisa PF13908.6 CDJ93143.1 - 0.3 11.3 0.0 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Bac_export_2 PF01312.19 CDJ93143.1 - 0.4 9.8 7.8 0.66 9.1 7.8 1.4 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family MtN3_slv PF03083.16 CDJ93143.1 - 0.95 9.6 9.8 0.074 13.1 3.1 2.1 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF5113 PF17140.4 CDJ93143.1 - 2.6 7.9 5.4 0.34 10.7 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) DUF4834 PF16118.5 CDJ93143.1 - 2.6 9.1 0.0 2.6 9.1 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Chs7 PF12271.8 CDJ93143.1 - 4.6 6.5 13.6 0.058 12.7 1.8 2.0 1 1 1 2 2 2 0 Chitin synthase export chaperone tRNA_bind_2 PF13725.6 CDJ93144.1 - 1.4e-06 28.2 4.3 1.4e-06 28.2 4.3 1.4 2 0 0 2 2 2 1 Possible tRNA binding domain Myosin_head PF00063.21 CDJ93145.1 - 4.8e-190 633.2 0.4 1.5e-120 403.5 0.1 2.1 1 1 1 2 2 2 2 Myosin head (motor domain) Myosin_TH1 PF06017.13 CDJ93145.1 - 1.9e-49 167.9 0.2 5e-49 166.5 0.3 1.7 2 0 0 2 2 2 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 CDJ93145.1 - 1.8e-16 59.7 0.0 5.4e-16 58.2 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDJ93145.1 - 2.4e-15 55.8 0.1 4.9e-15 54.9 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDJ93145.1 - 2.2e-09 36.9 0.0 5.4e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain AAA_16 PF13191.6 CDJ93145.1 - 0.0061 17.0 0.0 0.022 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain IQ PF00612.27 CDJ93145.1 - 0.037 13.8 1.2 0.12 12.3 1.2 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif AAA_22 PF13401.6 CDJ93145.1 - 0.069 13.4 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDJ93145.1 - 0.07 13.6 0.9 0.71 10.4 0.0 2.9 3 0 0 3 3 3 0 ABC transporter RNA_helicase PF00910.22 CDJ93145.1 - 0.08 13.3 0.1 1.2 9.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 CDJ93145.1 - 0.1 11.8 0.6 1.2 8.3 0.0 2.5 3 0 0 3 3 3 0 NB-ARC domain Hpr_kinase_C PF07475.12 CDJ93145.1 - 0.1 12.1 0.1 8.6 5.9 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Sigma54_activat PF00158.26 CDJ93145.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PocR PF10114.9 CDJ93145.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Sensory domain found in PocR 7tm_1 PF00001.21 CDJ93146.1 - 2.4e-06 27.1 4.8 2.9e-06 26.8 4.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDJ93146.1 - 3.7e-06 26.4 1.9 4.8e-06 26.1 1.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 CDJ93146.1 - 8.5e-05 22.3 4.7 0.00011 22.0 4.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.15 CDJ93146.1 - 0.016 15.2 1.1 0.02 14.9 0.9 1.3 1 1 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa 7TM_GPCR_Srsx PF10320.9 CDJ93146.1 - 0.05 13.0 2.7 0.068 12.5 2.7 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Cupin_4 PF08007.12 CDJ93150.1 - 8.9e-51 173.2 0.0 1.2e-50 172.8 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 CDJ93150.1 - 2.4e-06 27.5 0.0 0.00027 20.7 0.0 2.8 2 1 0 2 2 2 1 Cupin-like domain Cupin_1 PF00190.22 CDJ93150.1 - 0.049 13.2 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Cupin AAA PF00004.29 CDJ93151.1 - 3e-41 140.9 0.0 6.8e-41 139.8 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CDJ93151.1 - 5.4e-09 35.9 0.0 1.1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CDJ93151.1 - 4.4e-06 26.9 0.0 1.1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDJ93151.1 - 7.5e-06 26.3 0.4 0.0029 17.9 0.1 2.4 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 CDJ93151.1 - 2.9e-05 23.4 0.0 5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 CDJ93151.1 - 0.00022 21.8 0.1 0.0014 19.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CDJ93151.1 - 0.00049 20.4 0.1 0.0069 16.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CDJ93151.1 - 0.0005 19.9 0.0 0.00091 19.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Prot_ATP_OB_N PF17758.1 CDJ93151.1 - 0.00065 19.3 0.0 0.002 17.7 0.0 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain AAA_5 PF07728.14 CDJ93151.1 - 0.002 18.1 0.2 0.011 15.7 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CDJ93151.1 - 0.0027 17.7 0.1 0.027 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ93151.1 - 0.0033 17.8 0.1 0.047 14.1 0.1 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 CDJ93151.1 - 0.0081 16.0 0.0 0.036 13.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF3363 PF11843.8 CDJ93151.1 - 0.012 14.5 0.1 0.018 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) AAA_33 PF13671.6 CDJ93151.1 - 0.015 15.5 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CDJ93151.1 - 0.023 15.1 0.0 0.17 12.3 0.0 2.2 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 CDJ93151.1 - 0.033 13.9 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 CDJ93151.1 - 0.038 13.3 0.4 0.57 9.5 0.0 2.4 2 1 1 3 3 3 0 KaiC NB-ARC PF00931.22 CDJ93151.1 - 0.048 12.8 0.1 0.74 8.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain TIP49 PF06068.13 CDJ93151.1 - 0.057 12.6 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_25 PF13481.6 CDJ93151.1 - 0.079 12.5 0.5 3.6 7.1 0.1 2.3 1 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CDJ93151.1 - 0.093 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CDJ93151.1 - 0.14 11.9 0.1 0.33 10.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDJ93151.1 - 0.48 9.9 1.7 0.55 9.7 0.1 2.0 2 1 0 2 2 2 0 P-loop containing dynein motor region HTH_38 PF13936.6 CDJ93152.1 - 0.057 13.2 1.4 12 5.7 0.1 4.7 5 0 0 5 5 5 0 Helix-turn-helix domain Metal_resist PF13801.6 CDJ93152.1 - 0.86 9.8 16.2 8.7 6.6 0.5 5.2 4 1 1 5 5 5 0 Heavy-metal resistance CtnDOT_TraJ PF07863.11 CDJ93152.1 - 1.7 9.3 3.4 14 6.4 0.2 2.9 1 1 1 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon PT-VENN PF04829.13 CDJ93152.1 - 3.2 7.9 8.6 12 6.1 0.1 5.0 6 0 0 6 6 6 0 Pre-toxin domain with VENN motif Myosin_head PF00063.21 CDJ93153.1 - 5.5e-105 352.1 0.1 7.1e-105 351.7 0.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 CDJ93153.1 - 2.5e-49 167.5 0.2 7e-49 166.0 0.3 1.7 2 0 0 2 2 2 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 CDJ93153.1 - 1.1e-16 60.4 0.0 3.9e-16 58.6 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDJ93153.1 - 1.9e-15 56.2 0.1 3.6e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDJ93153.1 - 1.6e-09 37.3 0.0 3.9e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.27 CDJ93153.1 - 0.031 14.1 1.2 0.087 12.7 1.2 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif GNAT_acetyltr_2 PF13718.6 CDJ93154.1 - 1.7e-90 302.4 0.1 6.6e-90 300.5 0.0 2.0 2 0 0 2 2 2 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 CDJ93154.1 - 2.2e-64 217.4 8.8 3.2e-64 216.9 8.8 1.3 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 CDJ93154.1 - 4.2e-53 179.8 0.0 9e-53 178.7 0.0 1.6 1 0 0 1 1 1 1 Helicase Acetyltransf_7 PF13508.7 CDJ93154.1 - 0.00067 20.0 0.0 0.0049 17.3 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDJ93154.1 - 0.0022 18.2 0.0 0.0056 16.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family AAA_30 PF13604.6 CDJ93154.1 - 0.0025 17.5 0.0 2.4 7.8 0.0 3.2 3 1 0 3 3 3 2 AAA domain GvpL_GvpF PF06386.11 CDJ93154.1 - 0.11 12.4 1.6 11 5.8 0.4 2.7 3 0 0 3 3 3 0 Gas vesicle synthesis protein GvpL/GvpF Ras PF00071.22 CDJ93155.1 - 8.3e-63 210.8 0.1 9.9e-63 210.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ93155.1 - 2.6e-33 114.8 0.1 4.9e-33 113.9 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ93155.1 - 6.3e-13 48.6 0.0 7.5e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ93155.1 - 3.9e-05 23.7 0.0 6.1e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDJ93155.1 - 0.00018 21.0 0.0 0.00026 20.4 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CDJ93155.1 - 0.00057 19.8 0.1 0.26 11.2 0.0 2.4 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CDJ93155.1 - 0.00065 19.3 0.0 0.0043 16.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 CDJ93155.1 - 0.0088 15.8 0.1 0.019 14.7 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDJ93155.1 - 0.03 14.6 0.1 0.24 11.7 0.1 2.3 1 1 2 3 3 3 0 AAA domain DAP3 PF10236.9 CDJ93155.1 - 0.065 12.4 0.0 0.15 11.2 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 zf-BED PF02892.15 CDJ93156.1 - 0.00018 21.5 0.5 0.00031 20.7 0.5 1.4 1 0 0 1 1 1 1 BED zinc finger TFIIA PF03153.13 CDJ93156.1 - 0.0035 17.4 41.6 0.019 15.0 36.3 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Peptidase_S49_N PF08496.10 CDJ93156.1 - 0.032 14.3 10.8 0.077 13.1 10.8 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CTU2 PF10288.9 CDJ93156.1 - 0.06 13.6 9.6 0.21 11.8 9.3 2.1 2 0 0 2 2 1 0 Cytoplasmic tRNA 2-thiolation protein 2 MecA PF05389.12 CDJ93156.1 - 0.087 12.4 11.2 0.059 13.0 9.1 1.8 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) MAJIN PF15077.6 CDJ93156.1 - 0.17 11.6 7.3 0.4 10.4 7.3 1.6 1 0 0 1 1 1 0 Membrane-anchored junction protein Pinin_SDK_memA PF04696.13 CDJ93156.1 - 0.31 11.1 24.1 0.7 10.0 24.1 1.6 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Peroxin-13_N PF04088.13 CDJ93156.1 - 0.41 10.9 6.6 1.1 9.5 6.6 1.7 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Tim54 PF11711.8 CDJ93156.1 - 0.52 9.0 7.4 0.97 8.2 7.4 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Dynactin_p62 PF05502.13 CDJ93156.1 - 0.66 8.7 15.8 1.2 7.8 15.8 1.4 1 0 0 1 1 1 0 Dynactin p62 family Muted PF14942.6 CDJ93156.1 - 0.71 10.2 16.0 1.9 8.8 16.0 1.8 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Endonuc_Holl PF10107.9 CDJ93156.1 - 0.84 9.5 7.2 1.7 8.5 7.2 1.5 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase RR_TM4-6 PF06459.12 CDJ93156.1 - 1 9.2 17.3 0.32 10.8 13.5 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 EIIBC-GUT_N PF03612.14 CDJ93156.1 - 1.1 8.9 9.5 2.2 8.0 9.5 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus FPN1 PF06963.12 CDJ93156.1 - 1.1 7.7 3.8 1.6 7.2 3.8 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) FTO_NTD PF12933.7 CDJ93156.1 - 1.4 8.1 11.2 2.9 7.0 11.2 1.4 1 0 0 1 1 1 0 FTO catalytic domain Rxt3 PF08642.10 CDJ93156.1 - 1.5 9.6 5.6 4.5 8.1 5.6 1.8 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 PepSY_TM PF03929.16 CDJ93156.1 - 1.7 8.2 7.9 3.8 7.1 7.9 1.5 1 0 0 1 1 1 0 PepSY-associated TM region UPF0560 PF10577.9 CDJ93156.1 - 2.5 6.5 25.7 4.5 5.6 25.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Baculo_PP31 PF05311.11 CDJ93156.1 - 2.6 7.5 10.4 5.5 6.4 10.4 1.5 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Connexin PF00029.19 CDJ93156.1 - 2.7 7.7 5.9 4.5 7.0 5.9 1.3 1 0 0 1 1 1 0 Connexin DUF4746 PF15928.5 CDJ93156.1 - 2.8 7.3 7.9 3.2 7.1 5.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) O-antigen_lig PF13425.6 CDJ93156.1 - 3 6.5 6.0 4 6.1 6.0 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein AIF_C PF14721.6 CDJ93156.1 - 3.3 8.1 8.7 40 4.6 9.6 2.3 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term GNAT_acetyltr_2 PF13718.6 CDJ93156.1 - 3.8 6.8 10.3 9.5 5.5 10.3 1.6 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Mcm10 PF09332.11 CDJ93156.1 - 3.8 6.8 17.2 9.6 5.5 17.2 1.7 1 0 0 1 1 1 0 Mcm10 replication factor DUF1644 PF07800.12 CDJ93156.1 - 4 7.5 9.6 1.2 9.1 5.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) Membralin PF09746.9 CDJ93156.1 - 4.2 6.3 7.7 6.8 5.6 7.7 1.3 1 0 0 1 1 1 0 Tumour-associated protein V_ATPase_I PF01496.19 CDJ93156.1 - 4.2 5.2 13.0 5.9 4.7 13.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Plasmodium_Vir PF05795.11 CDJ93156.1 - 5 6.4 5.6 9.3 5.5 5.6 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein eIF-3_zeta PF05091.12 CDJ93156.1 - 5.8 5.8 17.8 9.5 5.1 17.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 CDJ93156.1 - 6.1 5.5 15.5 11 4.6 15.5 1.4 1 0 0 1 1 1 0 Presenilin Folliculin PF11704.8 CDJ93156.1 - 7.4 6.4 15.3 9.4 6.1 14.1 1.7 2 0 0 2 2 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport ALMT PF11744.8 CDJ93156.1 - 7.4 5.3 14.4 13 4.5 14.4 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter TERB2 PF15101.6 CDJ93156.1 - 7.7 6.5 18.4 21 5.1 18.4 1.7 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Suf PF05843.14 CDJ93156.1 - 9.6 6.1 19.3 2 8.4 15.5 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.10 CDJ93156.1 - 9.7 4.7 14.8 0.57 8.8 9.7 1.5 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Adeno_E1B_55K PF01696.17 CDJ93157.1 - 0.12 11.0 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen UCH PF00443.29 CDJ93158.1 - 1.3e-40 139.6 0.0 2.5e-40 138.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ93158.1 - 9.8e-21 74.7 0.4 2.9e-20 73.1 0.0 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Snf7 PF03357.21 CDJ93159.1 - 1.3e-35 122.6 7.9 1.8e-35 122.0 7.9 1.2 1 0 0 1 1 1 1 Snf7 APG6_N PF17675.1 CDJ93159.1 - 4.3e-05 24.1 5.3 0.035 14.6 1.2 2.5 2 0 0 2 2 2 2 Apg6 coiled-coil region PspA_IM30 PF04012.12 CDJ93159.1 - 0.00024 20.8 12.5 0.00059 19.5 12.5 1.6 1 1 0 1 1 1 1 PspA/IM30 family Phasin PF05597.11 CDJ93159.1 - 0.002 18.2 2.2 0.027 14.5 0.3 2.5 2 0 0 2 2 2 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Filament PF00038.21 CDJ93159.1 - 0.0025 17.4 9.9 0.0037 16.9 9.9 1.2 1 0 0 1 1 1 1 Intermediate filament protein STAT_alpha PF01017.20 CDJ93159.1 - 0.012 15.5 2.8 0.025 14.5 2.8 1.5 1 0 0 1 1 1 0 STAT protein, all-alpha domain FapA PF03961.13 CDJ93159.1 - 0.033 12.8 5.1 0.042 12.4 4.4 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A DASH_Dad2 PF08654.10 CDJ93159.1 - 0.049 14.1 0.8 2.4 8.6 0.1 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad2 TMF_TATA_bd PF12325.8 CDJ93159.1 - 0.057 13.6 0.4 0.057 13.6 0.4 3.0 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF948 PF06103.11 CDJ93159.1 - 0.072 13.4 1.6 4.9 7.5 0.5 3.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.8 CDJ93159.1 - 0.08 12.9 7.4 0.47 10.5 0.4 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF2228 PF10228.9 CDJ93159.1 - 0.094 12.4 1.2 1.8 8.2 0.0 2.9 2 1 0 3 3 3 0 Uncharacterised conserved protein (DUF2228) Laminin_II PF06009.12 CDJ93159.1 - 0.098 12.7 7.4 1.4 9.0 0.3 3.0 1 1 2 3 3 3 0 Laminin Domain II Spectrin PF00435.21 CDJ93159.1 - 0.14 12.7 8.6 0.51 10.8 3.9 3.6 1 1 2 3 3 3 0 Spectrin repeat GAS PF13851.6 CDJ93159.1 - 0.18 11.1 11.5 0.6 9.4 11.6 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding YlqD PF11068.8 CDJ93159.1 - 0.27 11.6 4.4 0.67 10.3 4.4 1.6 1 0 0 1 1 1 0 YlqD protein Not3 PF04065.15 CDJ93159.1 - 0.33 10.4 10.3 0.24 10.8 5.2 2.1 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component DUF1664 PF07889.12 CDJ93159.1 - 0.42 10.7 5.8 1.4 8.9 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 CDJ93159.1 - 0.51 10.7 7.0 0.45 10.9 0.2 3.4 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TraC PF07820.12 CDJ93159.1 - 0.54 10.6 3.9 2.2 8.7 0.2 3.1 3 0 0 3 3 3 0 TraC-like protein OmpH PF03938.14 CDJ93159.1 - 0.69 10.2 12.4 0.78 10.1 6.8 2.5 2 1 1 3 3 2 0 Outer membrane protein (OmpH-like) TPR_MLP1_2 PF07926.12 CDJ93159.1 - 0.72 9.9 9.4 0.19 11.8 3.9 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Cluap1 PF10234.9 CDJ93159.1 - 0.74 9.2 13.3 0.63 9.4 4.7 2.2 1 1 1 2 2 2 0 Clusterin-associated protein-1 SlyX PF04102.12 CDJ93159.1 - 0.76 10.4 4.2 10 6.8 0.1 3.3 2 2 1 3 3 3 0 SlyX Ax_dynein_light PF10211.9 CDJ93159.1 - 0.9 9.5 8.4 0.49 10.3 4.8 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain UPF0242 PF06785.11 CDJ93159.1 - 0.91 9.6 10.3 0.23 11.6 0.2 2.4 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 CDJ93159.1 - 1.3 9.2 5.6 1.7 8.8 0.2 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family PCRF PF03462.18 CDJ93159.1 - 2 8.3 8.7 9.3 6.1 1.7 2.4 1 1 1 2 2 2 0 PCRF domain FUSC PF04632.12 CDJ93159.1 - 2.5 6.5 4.4 3.7 6.0 4.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2203 PF09969.9 CDJ93159.1 - 2.9 8.6 5.8 2.9 8.7 2.0 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) FlaC_arch PF05377.11 CDJ93159.1 - 3 8.3 5.5 1.2 9.6 0.1 3.1 4 0 0 4 4 2 0 Flagella accessory protein C (FlaC) Occludin_ELL PF07303.13 CDJ93159.1 - 3.3 8.5 6.6 5.1 7.9 2.2 2.9 1 1 1 2 2 2 0 Occludin homology domain DUF724 PF05266.14 CDJ93159.1 - 6.2 6.6 11.1 8.1 6.2 4.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 CDJ93159.1 - 6.4 6.0 10.5 14 4.9 10.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 CDJ93159.1 - 7.2 6.9 9.4 2.1 8.6 1.0 3.1 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 ABC_tran_CTD PF16326.5 CDJ93159.1 - 9.5 6.6 14.3 0.13 12.5 1.8 3.5 3 2 0 3 3 3 0 ABC transporter C-terminal domain LRR_4 PF12799.7 CDJ93160.1 - 3e-34 116.5 31.8 5.1e-09 36.3 1.5 6.4 3 1 0 6 6 6 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDJ93160.1 - 7.6e-25 87.4 18.4 7.1e-09 35.4 7.7 4.0 1 1 3 4 4 4 4 Leucine-rich repeat LRR_8 PF13855.6 CDJ93160.1 - 1.9e-20 72.4 31.6 1.3e-07 31.2 7.5 6.4 1 1 6 7 7 7 6 Leucine rich repeat LRR_1 PF00560.33 CDJ93160.1 - 3e-05 24.0 26.0 3.4 8.6 1.2 8.9 10 0 0 10 10 10 2 Leucine Rich Repeat LRR_6 PF13516.6 CDJ93160.1 - 0.00059 19.7 25.1 1.9 8.7 0.1 7.8 7 1 1 8 8 8 3 Leucine Rich repeat FNIP PF05725.12 CDJ93160.1 - 0.0025 18.0 0.0 8.5 6.6 0.0 3.8 2 2 0 2 2 2 1 FNIP Repeat LRR_2 PF07723.13 CDJ93160.1 - 0.067 13.9 7.2 0.68 10.7 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat UB2H PF14814.6 CDJ93160.1 - 1.3 9.1 4.5 30 4.7 0.1 4.2 3 1 3 6 6 6 0 Bifunctional transglycosylase second domain CDI PF02234.19 CDJ93161.1 - 2.3e-11 43.7 0.1 4.5e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor CDI PF02234.19 CDJ93162.1 - 1.6e-11 44.2 0.1 2.3e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor HxlR PF01638.17 CDJ93162.1 - 0.029 14.2 0.0 0.51 10.2 0.0 2.2 2 0 0 2 2 2 0 HxlR-like helix-turn-helix PD40 PF07676.12 CDJ93163.1 - 2e-33 113.6 3.5 4.5e-09 36.0 0.0 5.4 6 0 0 6 6 6 4 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 CDJ93163.1 - 0.017 14.9 0.1 0.9 9.2 0.0 2.2 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain OpuAC PF04069.12 CDJ93163.1 - 0.064 12.8 0.4 3.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Substrate binding domain of ABC-type glycine betaine transport system PD40 PF07676.12 CDJ93164.1 - 3.4e-48 160.7 4.9 3e-08 33.4 0.0 7.2 7 1 0 7 7 7 6 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 CDJ93164.1 - 2e-08 33.4 0.2 0.39 9.4 0.0 4.4 3 2 0 3 3 3 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region Pectate_lyase22 PF14583.6 CDJ93164.1 - 6.8e-06 25.0 1.8 0.041 12.5 0.1 3.9 3 1 1 4 4 4 2 Oligogalacturonate lyase OpuAC PF04069.12 CDJ93164.1 - 0.0059 16.2 0.6 0.13 11.8 0.0 2.6 3 0 0 3 3 3 1 Substrate binding domain of ABC-type glycine betaine transport system Speriolin_C PF15059.6 CDJ93164.1 - 0.12 12.5 0.0 0.65 10.1 0.0 2.0 2 0 0 2 2 2 0 Speriolin C-terminus Glyco_hydro_30C PF17189.4 CDJ93164.1 - 0.17 12.1 0.2 30 4.9 0.0 4.1 5 0 0 5 5 5 0 Glycosyl hydrolase family 30 beta sandwich domain Ovate PF04844.13 CDJ93165.1 - 0.082 12.9 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 Transcriptional repressor, ovate Col_cuticle_N PF01484.17 CDJ93166.1 - 1.3e-19 70.0 0.8 1.6e-19 69.7 0.8 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ93166.1 - 1.3e-18 66.5 129.2 1.1e-05 25.0 52.8 4.9 3 1 1 4 4 4 4 Collagen triple helix repeat (20 copies) Collagen PF01391.18 CDJ93167.1 - 1.5e-24 85.5 159.9 6.4e-07 29.0 43.8 4.2 3 1 1 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ93167.1 - 1.5e-19 69.8 0.9 1.9e-19 69.5 0.9 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ93168.1 - 7.2e-12 44.9 84.5 3.4e-06 26.7 46.5 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) MFS_1 PF07690.16 CDJ93169.1 - 2.7e-13 49.6 22.6 4.4e-08 32.5 7.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 CDJ93170.1 - 2.2e-27 95.9 28.4 1.3e-26 93.4 28.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ93170.1 - 2e-22 79.7 21.5 2.7e-22 79.2 21.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Metallophos PF00149.28 CDJ93171.1 - 7.2e-22 78.9 0.5 1.1e-21 78.3 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pre-SET PF05033.16 CDJ93172.1 - 6.8e-08 33.1 3.8 1.8e-07 31.8 3.8 1.7 1 0 0 1 1 1 1 Pre-SET motif Tyrosinase PF00264.20 CDJ93172.1 - 0.0046 17.3 0.2 0.016 15.5 0.0 1.9 2 0 0 2 2 2 1 Common central domain of tyrosinase UPF0058 PF01893.16 CDJ93172.1 - 0.052 13.8 0.0 0.41 11.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0058 Kinesin PF00225.23 CDJ93173.1 - 0.066 12.1 0.0 0.081 11.8 0.0 1.1 1 0 0 1 1 1 0 Kinesin motor domain DUF1435 PF07256.12 CDJ93174.1 - 0.17 12.0 0.0 0.5 10.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1435) CD20 PF04103.15 CDJ93175.1 - 0.00068 19.8 7.2 0.00068 19.8 7.2 1.9 1 1 1 2 2 2 1 CD20-like family DUF981 PF06168.11 CDJ93175.1 - 0.00076 19.4 3.3 0.0013 18.7 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF981) DUF4383 PF14325.6 CDJ93175.1 - 0.011 16.0 0.4 0.019 15.3 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4383) Trep_Strep PF09605.10 CDJ93175.1 - 0.017 15.1 7.6 0.029 14.4 7.6 1.4 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Phage_holin_3_6 PF07332.11 CDJ93175.1 - 0.23 11.5 6.7 0.87 9.6 0.4 2.3 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III TssN PF17555.2 CDJ93175.1 - 1.4 8.2 9.4 1.8 7.9 9.4 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF2207 PF09972.9 CDJ93175.1 - 1.5 7.5 5.8 0.2 10.4 1.8 1.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF2070 PF09843.9 CDJ93175.1 - 9.3 4.4 11.7 11 4.1 11.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Coiled-coil_56 PF09813.9 CDJ93177.1 - 2.6e-11 43.5 0.2 4.3e-11 42.8 0.1 1.3 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 56 COX6C PF02937.15 CDJ93177.1 - 0.00063 19.8 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIc AAA_assoc_C PF09821.9 CDJ93177.1 - 0.051 14.1 0.2 0.085 13.4 0.2 1.5 1 0 0 1 1 1 0 C-terminal AAA-associated domain FWWh PF14922.6 CDJ93177.1 - 0.075 13.0 0.1 0.095 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function Cyt_b-c1_8 PF10890.8 CDJ93177.1 - 0.1 13.0 0.2 0.2 12.1 0.2 1.6 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 Bim_N PF06773.11 CDJ93177.1 - 0.9 9.3 2.2 4.4 7.1 0.2 2.1 2 0 0 2 2 2 0 Bim protein N-terminus PMSR PF01625.21 CDJ93178.1 - 2.9e-36 124.9 4.7 4.9e-36 124.2 4.7 1.3 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase HHH_3 PF12836.7 CDJ93178.1 - 0.098 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF4298 PF14131.6 CDJ93178.1 - 0.13 12.3 3.5 0.26 11.3 3.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) Arm PF00514.23 CDJ93179.1 - 1 9.5 0.0 1 9.5 0.0 5.1 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat TTR-52 PF01060.23 CDJ93180.1 - 3.1e-11 43.8 0.2 5.5e-11 43.0 0.2 1.4 1 0 0 1 1 1 1 Transthyretin-like family DUF4198 PF10670.9 CDJ93180.1 - 0.0034 17.8 0.0 0.0045 17.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4198) DUF3823 PF12866.7 CDJ93180.1 - 0.012 15.9 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3823) N-terminal domain CarboxypepD_reg PF13620.6 CDJ93180.1 - 0.021 15.1 0.0 0.028 14.7 0.0 1.2 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain FixH PF05751.11 CDJ93180.1 - 0.13 12.3 0.1 0.16 12.0 0.1 1.1 1 0 0 1 1 1 0 FixH NDUF_B8 PF05821.11 CDJ93181.1 - 1.3e-82 275.9 3.7 1.5e-82 275.7 3.7 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Hist_deacetyl PF00850.19 CDJ93182.1 - 6.5e-76 255.7 0.0 9.9e-76 255.1 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain ING PF12998.7 CDJ93182.1 - 3.3e-17 62.9 2.8 3.3e-17 62.9 2.8 2.2 3 0 0 3 3 3 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CDJ93182.1 - 3.6e-05 23.6 10.0 7.1e-05 22.6 10.0 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CDJ93182.1 - 0.0028 17.9 1.0 0.0092 16.2 1.0 1.9 1 0 0 1 1 1 1 PHD-like zinc-binding domain bMG10 PF17973.1 CDJ93182.1 - 0.018 15.2 0.1 0.04 14.1 0.1 1.5 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG10 domain DUF3450 PF11932.8 CDJ93182.1 - 0.12 11.7 3.5 0.28 10.5 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CorA PF01544.18 CDJ93182.1 - 0.3 10.4 2.0 0.71 9.1 2.0 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Pkinase PF00069.25 CDJ93183.1 - 2.1e-40 138.8 0.0 3e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ93183.1 - 2.1e-37 128.8 0.0 2.9e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ93183.1 - 2.8e-05 23.1 0.0 5.6e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDJ93183.1 - 0.00071 19.0 0.2 0.0012 18.2 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TMPIT PF07851.13 CDJ93184.1 - 1.2e-88 297.5 6.0 1.4e-88 297.3 6.0 1.0 1 0 0 1 1 1 1 TMPIT-like protein PMP1_2 PF08114.11 CDJ93184.1 - 0.062 13.1 0.1 0.16 11.7 0.1 1.7 1 0 0 1 1 1 0 ATPase proteolipid family Methyltransf_23 PF13489.6 CDJ93185.1 - 8.9e-06 25.6 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 CDJ93185.1 - 4.2e-05 23.3 0.0 5.9e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 CDJ93185.1 - 0.0089 16.7 0.0 0.019 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ93185.1 - 0.013 15.3 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ93185.1 - 0.031 14.9 0.0 0.056 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AvrM_N PF18247.1 CDJ93185.1 - 0.092 12.7 0.0 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 Flax-rust effector AvrM N-terminal domain Rad21_Rec8_N PF04825.13 CDJ93186.1 - 1.9e-39 134.2 0.0 3.5e-39 133.4 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CDJ93186.1 - 1.7e-17 62.4 0.3 5.7e-17 60.7 0.1 2.0 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 CDJ93186.1 - 0.00016 21.7 0.0 0.00057 19.9 0.0 1.9 2 1 1 3 3 3 1 Segregation and condensation protein ScpA ALG11_N PF15924.5 CDJ93187.1 - 3.3e-87 291.9 0.0 4.5e-87 291.5 0.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 CDJ93187.1 - 3.3e-24 85.3 0.1 5.8e-24 84.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CDJ93187.1 - 1.3e-11 45.1 0.0 3.5e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Synaptobrevin PF00957.21 CDJ93188.1 - 2.4e-16 59.3 0.8 4.3e-16 58.5 0.8 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CDJ93188.1 - 5.9e-08 32.6 0.0 1.1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Nsp1_C PF05064.13 CDJ93188.1 - 0.027 14.3 0.1 0.064 13.1 0.1 1.6 1 0 0 1 1 1 0 Nsp1-like C-terminal region MIS13 PF08202.11 CDJ93188.1 - 0.23 10.7 2.9 2 7.6 0.0 2.0 1 1 1 2 2 2 0 Mis12-Mtw1 protein family His_Phos_2 PF00328.22 CDJ93189.1 - 7.3e-29 101.3 0.0 2.7e-25 89.6 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) LAMTOR5 PF16672.5 CDJ93190.1 - 1.9e-16 59.8 0.1 2.1e-16 59.6 0.1 1.0 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 DUF2173 PF09941.9 CDJ93190.1 - 0.018 15.3 0.0 0.025 14.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2173) Urm1 PF09138.11 CDJ93191.1 - 2.2e-30 104.9 0.0 2.5e-30 104.7 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) Patched PF02460.18 CDJ93192.1 - 2.7e-27 95.3 0.4 3.3e-27 95.0 0.4 1.0 1 0 0 1 1 1 1 Patched family Patched PF02460.18 CDJ93193.1 - 3.4e-113 379.4 0.4 1.6e-94 317.6 0.1 2.0 1 1 1 2 2 2 2 Patched family Sterol-sensing PF12349.8 CDJ93193.1 - 1.5e-26 93.1 3.8 1.6e-26 93.0 2.3 1.8 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 CDJ93193.1 - 5.3e-08 32.2 4.4 8.5e-08 31.5 4.4 1.2 1 0 0 1 1 1 1 MMPL family FTA4 PF13093.6 CDJ93195.1 - 0.083 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Ground-like PF04155.18 CDJ93198.1 - 0.00038 21.0 0.0 0.0014 19.2 0.0 2.0 1 0 0 1 1 1 1 Ground-like domain Tad_C PF09977.9 CDJ93198.1 - 0.015 16.5 1.0 0.028 15.7 1.0 1.4 1 0 0 1 1 1 0 Putative Tad-like Flp pilus-assembly SKA1 PF07160.12 CDJ93198.1 - 0.1 12.5 2.8 0.19 11.5 2.8 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF3337 PF11816.8 CDJ93198.1 - 0.11 12.4 1.1 0.18 11.7 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) DDE_Tnp_1_2 PF13586.6 CDJ93198.1 - 0.18 12.2 0.8 0.3 11.5 0.2 1.7 2 0 0 2 2 2 0 Transposase DDE domain cwf18 PF08315.12 CDJ93199.1 - 4.8e-31 108.2 13.1 6.2e-31 107.8 13.1 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor CdvA PF18822.1 CDJ93199.1 - 0.041 13.7 12.9 0.34 10.7 0.5 2.3 2 1 0 2 2 2 0 CdvA-like coiled-coil domain DUF1104 PF06518.11 CDJ93199.1 - 0.078 13.4 11.8 1.7 9.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) Vfa1 PF08432.10 CDJ93199.1 - 6.8 7.0 14.8 17 5.7 0.1 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 CAP PF00188.26 CDJ93200.1 - 8.5e-14 52.5 3.6 1.3e-13 51.9 3.6 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ93200.1 - 0.0058 16.9 2.6 0.0086 16.3 1.5 1.8 2 0 0 2 2 2 1 Ancylostoma-associated secreted protein related Vinculin PF01044.19 CDJ93201.1 - 0 1315.2 15.3 6.8e-294 977.9 8.5 2.0 1 1 1 2 2 2 2 Vinculin family I_LWEQ PF01608.17 CDJ93201.1 - 0.0018 18.5 19.7 0.046 14.0 0.8 4.6 4 2 1 5 5 5 2 I/LWEQ domain Abi_C PF14355.6 CDJ93201.1 - 0.064 13.4 0.0 1.9 8.6 0.0 3.5 3 1 1 4 4 4 0 Abortive infection C-terminus DNA_repr_REX1B PF14966.6 CDJ93201.1 - 0.091 13.4 1.2 0.76 10.5 0.0 3.1 3 0 0 3 3 3 0 DNA repair REX1-B F_actin_bind PF08919.10 CDJ93201.1 - 0.38 10.9 2.3 14 5.8 0.0 4.1 3 0 0 3 3 3 0 F-actin binding Dynactin_p22 PF07426.11 CDJ93201.1 - 5.3 6.9 7.8 1.3 8.9 0.4 3.6 3 2 0 3 3 3 0 Dynactin subunit p22 DUF883 PF05957.13 CDJ93201.1 - 6.2 7.5 14.8 11 6.8 1.0 4.9 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF883) MCPsignal PF00015.21 CDJ93203.1 - 0.023 14.5 1.3 0.032 14.1 0.6 1.5 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DHR10 PF18595.1 CDJ93203.1 - 0.063 13.3 2.5 0.37 10.8 0.1 2.6 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain RRM_1 PF00076.22 CDJ93204.1 - 1.1e-18 66.8 0.0 1.4e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ93204.1 - 2e-06 27.8 0.0 3.5e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 CDJ93204.1 - 0.00039 20.0 0.0 0.00047 19.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ93204.1 - 0.074 12.9 0.0 0.091 12.6 0.0 1.1 1 0 0 1 1 1 0 Occluded RNA-recognition motif KorB_C PF06613.11 CDJ93204.1 - 0.083 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 KorB C-terminal beta-barrel domain Laminin_G_1 PF00054.23 CDJ93204.1 - 0.17 12.1 0.0 0.28 11.4 0.0 1.2 1 0 0 1 1 1 0 Laminin G domain PHM7_cyt PF14703.6 CDJ93204.1 - 0.22 11.7 0.0 0.38 11.0 0.0 1.4 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter RNB PF00773.19 CDJ93205.1 - 2.3e-106 355.8 0.0 3.5e-106 355.2 0.0 1.3 1 0 0 1 1 1 1 RNB domain Dis3l2_C_term PF17877.1 CDJ93205.1 - 1.1e-24 86.5 0.3 4.1e-24 84.7 0.0 2.2 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 CDJ93205.1 - 2.3e-23 82.0 0.0 9.7e-23 80.0 0.0 2.2 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 CDJ93205.1 - 7.2e-06 25.8 0.0 4.5e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 Rrp44-like cold shock domain UPF0029 PF01205.19 CDJ93206.1 - 3.2e-35 120.6 0.0 5.8e-35 119.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 CDJ93206.1 - 4.3e-17 62.5 1.5 2.3e-16 60.1 1.5 2.1 1 1 0 1 1 1 1 RWD domain Polysacc_deac_1 PF01522.21 CDJ93206.1 - 0.036 14.0 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide deacetylase adh_short PF00106.25 CDJ93207.1 - 5.9e-29 100.9 0.7 3.9e-28 98.2 0.7 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ93207.1 - 1.2e-23 83.9 0.0 5.2e-23 81.8 0.1 1.9 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ93207.1 - 0.00031 20.7 0.1 0.0005 20.0 0.1 1.4 1 1 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 CDJ93207.1 - 0.016 15.3 0.1 0.023 14.8 0.1 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Epimerase PF01370.21 CDJ93207.1 - 0.023 14.2 0.1 0.12 11.8 0.1 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 CDJ93207.1 - 0.041 13.2 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ArdA PF07275.11 CDJ93207.1 - 0.13 12.8 0.0 0.33 11.5 0.0 1.6 2 0 0 2 2 2 0 Antirestriction protein (ArdA) Metallophos PF00149.28 CDJ93208.1 - 2.2e-37 129.6 0.0 2.8e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Moulting_cycle PF04870.16 CDJ93209.1 - 9e-11 41.6 7.8 2e-08 33.9 7.8 3.4 1 1 0 1 1 1 1 Moulting cycle 7TM_GPCR_Str PF10326.9 CDJ93209.1 - 0.00031 20.2 5.5 0.00049 19.5 5.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srd PF10317.9 CDJ93209.1 - 0.0046 16.2 2.9 0.0046 16.2 2.9 2.4 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srd Med12-PQL PF12144.8 CDJ93209.1 - 0.052 13.4 0.5 0.095 12.6 0.5 1.3 1 0 0 1 1 1 0 Eukaryotic Mediator 12 catenin-binding domain DUF1129 PF06570.11 CDJ93209.1 - 0.056 12.9 5.2 0.12 11.8 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) LtrA PF06772.11 CDJ93209.1 - 0.078 12.2 5.8 0.12 11.6 5.8 1.1 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) Methyltransf_21 PF05050.12 CDJ93210.1 - 5.1e-15 55.9 0.1 6.1e-15 55.7 0.1 1.0 1 0 0 1 1 1 1 Methyltransferase FkbM domain Thermopsin PF05317.11 CDJ93210.1 - 0.029 13.8 0.2 0.03 13.8 0.2 1.1 1 0 0 1 1 1 0 Thermopsin His_Phos_2 PF00328.22 CDJ93211.1 - 2.1e-09 37.2 0.0 2.1e-07 30.7 0.1 2.6 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.22 CDJ93211.1 - 0.0006 19.6 0.0 0.00096 18.9 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ABC_membrane PF00664.23 CDJ93212.1 - 6.2e-132 439.3 32.3 1.6e-67 228.1 15.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ93212.1 - 6e-75 250.3 0.0 6.2e-37 127.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CDJ93212.1 - 4.4e-17 62.3 5.8 1.2e-07 31.4 0.0 4.2 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 CDJ93212.1 - 2.7e-10 39.6 0.3 4.3e-05 22.5 0.0 2.9 2 1 0 2 2 2 2 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 CDJ93212.1 - 1.1e-09 37.9 0.2 0.0009 18.6 0.0 3.5 4 0 0 4 4 4 2 Zeta toxin AAA_16 PF13191.6 CDJ93212.1 - 2.4e-09 37.8 0.6 0.0016 18.8 0.0 3.4 3 2 0 3 3 2 2 AAA ATPase domain AAA PF00004.29 CDJ93212.1 - 3e-09 37.4 0.1 0.25 11.8 0.0 4.6 4 1 0 4 4 3 3 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 CDJ93212.1 - 1.1e-08 35.2 0.4 0.07 12.9 0.0 4.2 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CDJ93212.1 - 5.9e-07 29.1 0.3 0.053 13.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CDJ93212.1 - 5.9e-07 29.5 0.1 0.037 13.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 CDJ93212.1 - 6.4e-07 29.7 1.6 0.028 14.7 0.0 4.0 3 2 0 3 3 2 2 AAA domain Rad17 PF03215.15 CDJ93212.1 - 1e-06 28.8 0.0 0.023 14.7 0.0 2.7 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_5 PF07728.14 CDJ93212.1 - 9.2e-06 25.7 0.2 0.42 10.6 0.0 4.1 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 CDJ93212.1 - 1.7e-05 24.7 0.0 0.16 11.6 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 CDJ93212.1 - 0.00011 22.5 0.0 2.3 8.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.13 CDJ93212.1 - 0.00011 21.5 0.0 0.053 12.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 CDJ93212.1 - 0.00014 21.6 0.3 0.21 11.3 0.0 3.5 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CDJ93212.1 - 0.00017 22.2 0.0 0.46 11.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 CDJ93212.1 - 0.00019 21.6 4.4 0.57 10.4 0.3 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 CDJ93212.1 - 0.0004 19.9 0.0 0.56 9.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 CDJ93212.1 - 0.00045 20.3 0.0 0.53 10.3 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_25 PF13481.6 CDJ93212.1 - 0.00046 19.8 0.1 2.5 7.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain PRK PF00485.18 CDJ93212.1 - 0.00079 19.2 0.0 0.75 9.5 0.0 2.4 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 CDJ93212.1 - 0.00087 19.5 0.2 2.9 8.1 0.0 3.2 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CDJ93212.1 - 0.0009 19.6 0.0 2.3 8.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase G-alpha PF00503.20 CDJ93212.1 - 0.0016 17.7 0.0 0.59 9.2 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit ATP-synt_ab PF00006.25 CDJ93212.1 - 0.0021 17.8 0.0 0.12 12.1 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.23 CDJ93212.1 - 0.0024 17.9 0.0 1.1 9.4 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase NTPase_1 PF03266.15 CDJ93212.1 - 0.0027 17.6 0.4 23 4.9 0.0 3.8 4 0 0 4 4 3 0 NTPase AAA_24 PF13479.6 CDJ93212.1 - 0.0032 17.2 0.0 2.4 7.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CDJ93212.1 - 0.0033 17.2 0.9 21 4.8 0.0 4.2 4 0 0 4 4 4 0 IstB-like ATP binding protein NB-ARC PF00931.22 CDJ93212.1 - 0.0061 15.8 0.1 2.5 7.2 0.0 2.6 2 1 0 2 2 2 1 NB-ARC domain AAA_23 PF13476.6 CDJ93212.1 - 0.0088 16.6 4.2 3.5 8.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.20 CDJ93212.1 - 0.011 15.7 0.0 3.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase tRNA_lig_kinase PF08303.11 CDJ93212.1 - 0.012 15.7 0.0 9 6.4 0.0 3.5 3 0 0 3 3 3 0 tRNA ligase kinase domain Mg_chelatase PF01078.21 CDJ93212.1 - 0.014 14.8 0.0 2.6 7.3 0.0 2.9 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI KAP_NTPase PF07693.14 CDJ93212.1 - 0.033 13.4 0.0 2.1 7.5 0.0 2.5 2 0 0 2 2 2 0 KAP family P-loop domain DUF87 PF01935.17 CDJ93212.1 - 0.034 14.2 0.1 6 6.9 0.0 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain NACHT PF05729.12 CDJ93212.1 - 0.041 13.8 0.0 8.4 6.3 0.0 2.5 2 0 0 2 2 2 0 NACHT domain SRP54 PF00448.22 CDJ93212.1 - 0.046 13.3 0.0 6.6 6.3 0.0 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Guanylate_kin PF00625.21 CDJ93212.1 - 0.072 12.8 0.0 3.1 7.4 0.0 2.5 2 0 0 2 2 2 0 Guanylate kinase Septin PF00735.18 CDJ93212.1 - 0.084 12.1 0.0 4.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Septin Viral_helicase1 PF01443.18 CDJ93212.1 - 0.096 12.4 0.2 4.3 7.0 0.0 2.7 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 CDJ93212.1 - 0.097 13.0 0.0 17 5.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain Sterol-sensing PF12349.8 CDJ93212.1 - 9.7 6.0 9.9 0.29 11.0 0.2 3.2 3 0 0 3 3 3 0 Sterol-sensing domain of SREBP cleavage-activation HOOK PF05622.12 CDJ93216.1 - 5.3e-30 104.2 74.2 7.3e-30 103.8 74.2 1.0 1 0 0 1 1 1 1 HOOK protein Trypsin PF00089.26 CDJ93217.1 - 3.3e-58 197.1 0.1 3.9e-58 196.9 0.1 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CDJ93217.1 - 3.6e-05 24.7 0.0 6.7e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CDJ93217.1 - 5.8e-05 23.4 0.1 0.00012 22.5 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) HOOK PF05622.12 CDJ93218.1 - 1.2e-09 37.0 0.0 1.4e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 HOOK protein Pex14_N PF04695.13 CDJ93219.1 - 0.043 14.5 0.5 0.064 13.9 0.5 1.3 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RVT_1 PF00078.27 CDJ93220.1 - 2.9e-15 56.4 0.0 5.5e-15 55.5 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2_2 PF12756.7 CDJ93222.1 - 0.01 16.2 0.3 0.013 15.8 0.3 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 CDJ93224.1 - 3.3e-17 62.4 7.3 5.2e-17 61.7 7.3 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CDJ93224.1 - 0.0011 19.2 2.4 0.0017 18.6 2.4 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger Siva PF05458.12 CDJ93224.1 - 0.0099 15.6 3.2 0.014 15.1 3.2 1.2 1 0 0 1 1 1 1 Cd27 binding protein (Siva) zf-B_box PF00643.24 CDJ93224.1 - 0.35 11.1 5.7 1.1 9.5 5.7 1.8 1 1 0 1 1 1 0 B-box zinc finger Ephrin_rec_like PF07699.13 CDJ93224.1 - 0.36 10.6 6.1 0.26 11.1 1.4 2.5 2 1 1 3 3 3 0 Putative ephrin-receptor like UDPGT PF00201.18 CDJ93225.1 - 0.0059 15.4 0.0 0.0096 14.7 0.0 1.3 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase TBP PF00352.21 CDJ93226.1 - 3.6e-64 212.7 0.2 7.9e-31 105.9 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) UDPGT PF00201.18 CDJ93226.1 - 1.4e-52 179.2 0.0 1.8e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ93226.1 - 2.8e-12 46.9 0.0 1.1e-11 45.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain DUF3378 PF11858.8 CDJ93226.1 - 9.8e-05 22.4 0.0 0.27 11.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Neur_chan_memb PF02932.16 CDJ93227.1 - 0.0014 18.8 0.2 0.0014 18.7 0.2 1.4 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region CD52 PF15116.6 CDJ93227.1 - 0.37 10.8 2.2 1 9.4 1.4 2.1 1 1 1 2 2 2 0 CAMPATH-1 antigen Glyco_transf_7N PF13733.6 CDJ93228.1 - 6.2e-51 171.6 0.2 1.1e-50 170.7 0.2 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CDJ93228.1 - 5.3e-27 93.3 2.2 9.8e-27 92.4 2.2 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 CDJ93229.1 - 5.5e-51 171.7 0.2 1.1e-50 170.8 0.2 1.5 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CDJ93229.1 - 2.7e-27 94.2 2.5 5.9e-27 93.1 2.5 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7C PF02709.14 CDJ93230.1 - 7.2e-28 96.1 2.3 1.3e-27 95.3 2.3 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 CDJ93230.1 - 2.4e-08 33.7 1.8 4.2e-08 32.9 1.8 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 GMC_oxred_N PF00732.19 CDJ93230.1 - 0.008 15.6 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase CC PF04942.14 CDJ93231.1 - 1.7e-05 24.9 31.9 0.00066 19.8 9.6 4.7 5 0 0 5 5 5 3 CC domain Nudix_N_2 PF14803.6 CDJ93232.1 - 0.00014 21.7 2.0 0.00033 20.5 2.0 1.6 1 0 0 1 1 1 1 Nudix N-terminal DZR PF12773.7 CDJ93232.1 - 0.0095 15.9 1.2 0.023 14.7 1.2 1.6 1 0 0 1 1 1 1 Double zinc ribbon zinc-ribbons_6 PF07191.12 CDJ93232.1 - 0.067 13.2 1.4 0.19 11.8 1.4 1.7 1 0 0 1 1 1 0 zinc-ribbons zf-NADH-PPase PF09297.11 CDJ93232.1 - 0.46 10.2 3.8 0.58 9.9 0.7 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.6 CDJ93232.1 - 7.9 6.0 6.1 0.39 10.2 0.3 1.9 2 0 0 2 2 2 0 zinc-ribbon domain DUF2508 PF10704.9 CDJ93233.1 - 6.7 7.0 6.1 17 5.7 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) FERM_M PF00373.18 CDJ93234.1 - 6.7e-41 139.4 0.5 1.2e-40 138.6 0.5 1.4 1 0 0 1 1 1 1 FERM central domain Kindlin_2_N PF18124.1 CDJ93234.1 - 1.3e-35 121.4 0.5 3.1e-35 120.2 0.5 1.7 1 0 0 1 1 1 1 Kindlin-2 N-terminal domain PH PF00169.29 CDJ93234.1 - 1.1e-08 35.5 0.0 2.4e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 PH domain FERM_N PF09379.10 CDJ93234.1 - 0.012 15.5 0.2 0.24 11.3 0.0 2.7 2 1 0 2 2 2 0 FERM N-terminal domain PH_11 PF15413.6 CDJ93234.1 - 0.041 14.3 0.4 0.25 11.8 0.0 2.6 2 2 0 2 2 2 0 Pleckstrin homology domain PH_8 PF15409.6 CDJ93234.1 - 0.062 13.6 0.0 0.21 11.9 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain AAA_12 PF13087.6 CDJ93236.1 - 9.5e-39 133.1 0.0 2.6e-38 131.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CDJ93236.1 - 9.9e-16 58.3 0.2 2.4e-12 47.2 0.1 2.5 1 1 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.6 CDJ93236.1 - 0.031 14.1 0.1 0.07 13.0 0.1 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain NAD_binding_11 PF14833.6 CDJ93236.1 - 0.18 12.0 0.0 3.2 8.0 0.0 2.4 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase CbtA PF09490.10 CDJ93237.1 - 0.0061 16.4 0.0 0.018 14.9 0.0 1.7 2 0 0 2 2 2 1 Probable cobalt transporter subunit (CbtA) FAM163 PF15069.6 CDJ93237.1 - 0.017 15.6 0.5 0.017 15.6 0.5 3.8 4 1 1 5 5 5 0 FAM163 family EphA2_TM PF14575.6 CDJ93237.1 - 0.17 12.8 0.0 0.17 12.8 0.0 2.7 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain LAP1C PF05609.12 CDJ93237.1 - 0.21 10.7 18.1 0.33 10.0 18.1 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Macoilin PF09726.9 CDJ93237.1 - 2.8 6.4 11.5 4 5.9 11.5 1.2 1 0 0 1 1 1 0 Macoilin family HORMA PF02301.18 CDJ93238.1 - 5.6e-26 91.5 0.0 8.6e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 HORMA domain Cadherin PF00028.17 CDJ93239.1 - 3.6e-84 277.3 7.0 1.7e-12 47.6 0.0 12.6 11 3 0 11 11 11 10 Cadherin domain Cadherin_3 PF16184.5 CDJ93239.1 - 2.7e-08 33.8 3.5 0.39 10.7 0.1 6.6 7 0 0 7 7 7 2 Cadherin-like Cadherin_2 PF08266.12 CDJ93239.1 - 0.00017 21.4 0.6 0.08 12.8 0.0 4.3 6 0 0 6 6 6 1 Cadherin-like RET_CLD1 PF17756.1 CDJ93239.1 - 0.076 13.3 0.0 1.3 9.3 0.0 3.2 4 0 0 4 4 4 0 RET Cadherin like domain 1 Cadherin PF00028.17 CDJ93240.1 - 2.9e-168 546.9 9.8 2.3e-22 79.2 0.1 12.8 12 0 0 12 12 12 12 Cadherin domain Cadherin_2 PF08266.12 CDJ93240.1 - 3.1e-13 49.4 0.5 0.19 11.6 0.0 8.8 9 0 0 9 9 9 4 Cadherin-like Cadherin_pro PF08758.11 CDJ93240.1 - 9.3e-12 45.0 0.7 0.077 13.2 0.0 7.9 8 0 0 8 8 8 3 Cadherin prodomain like Laminin_G_2 PF02210.24 CDJ93240.1 - 0.00014 22.4 0.2 0.00069 20.2 0.1 2.3 2 0 0 2 2 2 1 Laminin G domain Cadherin_3 PF16184.5 CDJ93240.1 - 0.0063 16.5 18.3 3.8 7.5 0.0 7.5 7 0 0 7 7 7 2 Cadherin-like Laminin_G_1 PF00054.23 CDJ93240.1 - 0.056 13.7 0.0 0.2 11.8 0.0 2.0 1 0 0 1 1 1 0 Laminin G domain EGF_alliinase PF04863.13 CDJ93240.1 - 2.4 8.6 11.4 1.1 9.7 0.8 2.5 2 0 0 2 2 2 0 Alliinase EGF-like domain Rrp44_S1 PF17215.3 CDJ93240.1 - 3.3 7.7 8.2 24 5.0 0.0 4.9 6 0 0 6 6 6 0 S1 domain EGF PF00008.27 CDJ93240.1 - 5.7 7.3 12.6 2.9 8.3 5.9 2.4 2 0 0 2 2 2 0 EGF-like domain Not3 PF04065.15 CDJ93241.1 - 2.3e-71 239.9 27.7 3.1e-71 239.5 27.7 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 CDJ93241.1 - 4.3e-31 107.7 0.5 9.5e-31 106.6 0.5 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family PHM7_cyt PF14703.6 CDJ93241.1 - 0.00043 20.6 10.9 0.0055 17.0 11.1 2.5 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter Poty_PP PF08440.10 CDJ93241.1 - 0.095 11.8 2.9 0.2 10.7 2.9 1.5 1 0 0 1 1 1 0 Potyviridae polyprotein IFT20 PF14931.6 CDJ93241.1 - 3.1 8.0 17.6 0.34 11.1 5.1 2.9 1 1 2 3 3 3 0 Intraflagellar transport complex B, subunit 20 ZapB PF06005.12 CDJ93241.1 - 6.4 7.3 16.3 0.21 12.1 5.3 2.9 2 0 0 2 2 2 0 Cell division protein ZapB GreA_GreB_N PF03449.15 CDJ93242.1 - 0.029 14.5 6.1 0.036 14.2 4.3 2.2 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal DUF3251 PF11622.8 CDJ93242.1 - 0.14 11.8 1.2 4.2 7.0 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3251) Ferritin_2 PF13668.6 CDJ93242.1 - 0.2 11.8 0.2 0.42 10.8 0.1 1.6 2 0 0 2 2 2 0 Ferritin-like domain CheZ PF04344.13 CDJ93242.1 - 0.21 11.5 5.5 0.05 13.5 0.9 2.2 1 1 0 2 2 2 0 Chemotaxis phosphatase, CheZ DUF4407 PF14362.6 CDJ93242.1 - 0.57 9.5 12.0 5 6.4 11.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 CDJ93242.1 - 2.2 8.3 12.2 0.54 10.3 6.6 2.7 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 CDJ93242.1 - 2.5 8.8 7.2 1.8 9.3 2.3 2.8 2 1 0 3 3 3 0 Initiation control protein YabA Cation_ATPase_C PF00689.21 CDJ93243.1 - 7.8e-24 84.4 2.6 9e-24 84.2 2.6 1.0 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Ribosom_S12_S23 PF00164.25 CDJ93244.1 - 1e-41 141.1 0.3 1.1e-41 141.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Flavokinase PF01687.17 CDJ93245.1 - 1.1e-29 102.9 0.0 1.3e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase C1_1 PF00130.22 CDJ93246.1 - 2.5e-29 100.9 31.7 1.4e-14 53.7 12.6 2.2 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 CDJ93246.1 - 0.00017 21.8 20.4 0.0078 16.5 3.4 2.7 2 1 0 2 2 2 2 C1 domain zf-RING_9 PF13901.6 CDJ93246.1 - 0.014 15.4 23.6 0.078 13.0 7.9 2.2 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon FYVE_2 PF02318.16 CDJ93246.1 - 0.021 15.1 14.5 0.22 11.8 2.5 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING-like PF08746.11 CDJ93246.1 - 0.061 13.6 28.4 1 9.7 11.1 3.0 2 1 0 2 2 2 0 RING-like domain E6 PF00518.17 CDJ93246.1 - 0.2 12.1 11.7 0.06 13.8 2.2 2.1 2 0 0 2 2 2 0 Early Protein (E6) PHD PF00628.29 CDJ93246.1 - 0.52 10.2 26.2 0.98 9.4 8.6 3.0 2 1 0 2 2 2 0 PHD-finger JmjC PF02373.22 CDJ93247.1 - 2.6e-38 131.0 2.7 8.3e-38 129.3 2.7 2.0 1 0 0 1 1 1 1 JmjC domain, hydroxylase PLU-1 PF08429.11 CDJ93247.1 - 4.5e-32 111.6 5.2 4.5e-32 111.6 5.2 1.7 2 0 0 2 2 2 1 PLU-1-like protein zf-C5HC2 PF02928.16 CDJ93247.1 - 8e-16 58.2 8.3 8e-16 58.2 8.3 2.0 2 0 0 2 2 2 1 C5HC2 zinc finger JmjN PF02375.17 CDJ93247.1 - 3.6e-15 55.6 2.4 6.6e-15 54.8 1.0 2.3 2 0 0 2 2 2 1 jmjN domain ARID PF01388.21 CDJ93247.1 - 2.9e-14 53.5 0.4 6.3e-14 52.4 0.4 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 CDJ93247.1 - 1.8e-11 43.8 9.0 1.8e-11 43.8 9.0 2.1 2 0 0 2 2 2 1 PHD-finger Cript PF10235.9 CDJ93247.1 - 0.73 10.4 4.6 6.1 7.5 0.2 2.8 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT OrfB_Zn_ribbon PF07282.11 CDJ93247.1 - 5.3 7.0 6.2 4.4 7.3 1.4 2.7 1 1 1 2 2 2 0 Putative transposase DNA-binding domain FYVE_2 PF02318.16 CDJ93247.1 - 9.2 6.5 11.6 2 8.6 0.7 2.8 2 0 0 2 2 2 0 FYVE-type zinc finger Mob1_phocein PF03637.17 CDJ93249.1 - 0.033 14.2 0.0 0.041 13.9 0.0 1.1 1 0 0 1 1 1 0 Mob1/phocein family Pro_isomerase PF00160.21 CDJ93250.1 - 9.7e-51 172.2 0.0 1.2e-50 171.9 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3271 PF11675.8 CDJ93250.1 - 0.064 12.5 0.0 0.65 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3271) Exo_endo_phos_2 PF14529.6 CDJ93252.1 - 0.001 18.9 0.1 0.002 18.0 0.0 1.5 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Papo_T_antigen PF02380.15 CDJ93252.1 - 0.011 15.8 0.1 0.025 14.7 0.1 1.5 1 0 0 1 1 1 0 T-antigen specific domain Myco_arth_vir_N PF09610.10 CDJ93253.1 - 0.15 12.2 1.7 0.27 11.3 1.7 1.5 1 1 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) CHIP_TPR_N PF18391.1 CDJ93254.1 - 0.31 11.8 6.4 0.094 13.5 3.3 1.7 1 1 1 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain Pribosyltran PF00156.27 CDJ93256.1 - 2e-06 27.4 0.0 2.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 CDJ93256.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase MMADHC PF10229.9 CDJ93257.1 - 9.9e-82 274.7 0.1 1.2e-81 274.5 0.1 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein AAA_11 PF13086.6 CDJ93257.1 - 0.079 12.7 1.0 0.12 12.2 0.9 1.5 1 1 0 1 1 1 0 AAA domain Choline_kinase PF01633.20 CDJ93259.1 - 9.5e-14 51.5 0.0 1.2e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Optomotor-blind PF11078.8 CDJ93259.1 - 0.06 13.9 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 Optomotor-blind protein N-terminal region APH PF01636.23 CDJ93259.1 - 0.19 11.6 0.2 0.29 11.0 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Jnk-SapK_ap_N PF09744.9 CDJ93260.1 - 1.6e-30 106.4 12.3 1.6e-30 106.4 12.3 3.4 1 1 3 4 4 4 1 JNK_SAPK-associated protein-1 RILP PF11461.8 CDJ93260.1 - 7.9e-11 42.0 7.2 7.9e-11 42.0 7.2 3.0 3 1 1 4 4 1 1 Rab interacting lysosomal protein YabA PF06156.13 CDJ93260.1 - 0.03 15.0 7.5 0.03 15.0 7.5 4.1 1 1 3 4 4 4 0 Initiation control protein YabA DUF2935 PF11155.8 CDJ93260.1 - 0.035 14.4 1.1 0.035 14.4 1.1 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF2935) LMBR1 PF04791.16 CDJ93260.1 - 0.055 12.4 11.8 0.074 11.9 11.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Mod_r PF07200.13 CDJ93260.1 - 0.07 13.2 37.2 0.045 13.9 12.2 3.5 2 1 2 4 4 4 0 Modifier of rudimentary (Mod(r)) protein DUF1759 PF03564.15 CDJ93260.1 - 0.56 10.1 15.5 0.24 11.3 0.9 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1759) Baculo_PEP_C PF04513.12 CDJ93260.1 - 0.61 10.1 11.2 3.8 7.6 0.4 2.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.8 CDJ93260.1 - 0.93 9.6 34.6 2.4 8.3 14.5 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Prefoldin PF02996.17 CDJ93260.1 - 0.97 9.4 23.2 0.41 10.6 0.5 4.8 4 1 0 4 4 4 0 Prefoldin subunit PRKG1_interact PF15898.5 CDJ93260.1 - 1.1 10.2 35.6 0.7 10.8 6.0 3.4 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain GIT_CC PF16559.5 CDJ93260.1 - 1.3 8.9 33.2 0.2 11.6 1.2 5.2 3 2 3 6 6 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF948 PF06103.11 CDJ93260.1 - 1.5 9.2 12.4 3.8 7.8 1.7 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) WD40_alt PF14077.6 CDJ93260.1 - 1.6 8.7 6.5 0.32 10.9 1.5 2.5 2 1 0 2 2 2 0 Alternative WD40 repeat motif APG6_N PF17675.1 CDJ93260.1 - 1.7 9.2 47.1 7.2 7.1 15.3 3.5 1 1 2 3 3 3 0 Apg6 coiled-coil region HisKA_3 PF07730.13 CDJ93260.1 - 2.1 8.9 9.2 0.64 10.6 0.8 3.5 2 2 0 2 2 2 0 Histidine kinase FAM184 PF15665.5 CDJ93260.1 - 2.5 7.8 37.5 0.1 12.3 11.7 3.1 1 1 1 3 3 3 0 Family with sequence similarity 184, A and B FUSC PF04632.12 CDJ93260.1 - 2.8 6.4 9.2 2.8 6.4 4.0 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family TPR_MLP1_2 PF07926.12 CDJ93260.1 - 2.9 8.0 41.0 0.3 11.1 12.3 3.9 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein TACC_C PF05010.14 CDJ93260.1 - 3.4 7.4 36.4 8.6 6.1 5.5 3.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Sec20 PF03908.13 CDJ93260.1 - 4.8 7.2 13.8 0.57 10.1 1.0 3.3 2 1 1 3 3 3 0 Sec20 GAS PF13851.6 CDJ93260.1 - 6.7 6.0 42.2 0.24 10.7 14.8 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding MbeD_MobD PF04899.12 CDJ93260.1 - 6.9 6.9 13.4 3.6 7.8 0.4 4.3 3 2 1 4 4 4 0 MbeD/MobD like Lectin_N PF03954.14 CDJ93260.1 - 7.2 6.4 15.8 0.14 11.9 2.9 3.2 2 1 2 4 4 3 0 Hepatic lectin, N-terminal domain DUF1664 PF07889.12 CDJ93260.1 - 7.9 6.5 19.6 0.92 9.6 1.1 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF2115 PF09888.9 CDJ93260.1 - 8.3 6.9 11.6 14 6.2 0.4 3.2 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) HAUS-augmin3 PF14932.6 CDJ93260.1 - 8.6 5.8 38.0 0.15 11.6 12.2 3.1 1 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 KapB PF08810.10 CDJ93260.1 - 8.9 6.5 8.1 1.1 9.5 1.6 2.4 2 0 0 2 2 2 0 Kinase associated protein B Cmc1 PF08583.10 CDJ93261.1 - 4.8e-09 36.1 3.2 4.8e-09 36.1 3.2 1.6 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 CDJ93261.1 - 0.0031 17.6 0.4 0.0057 16.8 0.4 1.5 1 0 0 1 1 1 1 CHCH domain Ribosomal_L24e PF01246.20 CDJ93262.1 - 9.6e-32 109.0 2.9 9.6e-32 109.0 2.9 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e zf-C3HC4_5 PF17121.5 CDJ93262.1 - 0.079 12.9 1.0 0.14 12.0 1.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2175 PF09943.9 CDJ93262.1 - 1.3 9.4 6.1 0.33 11.3 0.3 2.3 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Glyco_hydro_38N PF01074.22 CDJ93263.1 - 2.8e-89 299.3 3.5 4.3e-89 298.7 3.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 CDJ93263.1 - 1.8e-30 106.6 0.2 5.9e-30 104.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 CDJ93263.1 - 1.4e-23 82.8 1.7 1.9e-23 82.4 0.3 2.0 2 0 0 2 2 2 1 Alpha mannosidase middle domain MbeD_MobD PF04899.12 CDJ93263.1 - 0.081 13.1 3.3 1.4 9.1 0.1 2.9 2 0 0 2 2 2 0 MbeD/MobD like Fib_alpha PF08702.10 CDJ93263.1 - 0.2 11.8 2.0 0.32 11.2 0.5 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family R3H PF01424.22 CDJ93265.1 - 7.6e-10 38.6 0.0 1.9e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 R3H domain UFC1 PF08694.11 CDJ93266.1 - 6.5e-76 253.2 0.1 7.6e-76 253.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 SLATT_5 PF18160.1 CDJ93266.1 - 0.0038 16.6 0.1 0.0057 16.0 0.1 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 5 RWD PF05773.22 CDJ93266.1 - 0.011 16.0 0.0 0.015 15.6 0.0 1.2 1 0 0 1 1 1 0 RWD domain UQ_con PF00179.26 CDJ93266.1 - 0.023 14.4 0.1 0.036 13.7 0.1 1.4 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme Mre11_DNA_bind PF04152.14 CDJ93267.1 - 1.4e-16 61.3 0.1 6.3e-16 59.2 0.0 2.1 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 CDJ93267.1 - 1.7e-09 38.5 0.3 2.8e-09 37.8 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDJ93267.1 - 1.4e-05 25.3 0.0 6.3e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Hormone_recep PF00104.30 CDJ93268.1 - 4.3e-05 23.2 0.0 0.0051 16.4 0.1 2.1 2 0 0 2 2 2 2 Ligand-binding domain of nuclear hormone receptor Rhomboid PF01694.22 CDJ93269.1 - 6.9e-26 91.0 12.1 1.1e-25 90.4 12.1 1.3 1 0 0 1 1 1 1 Rhomboid family Asp PF00026.23 CDJ93270.1 - 3.9e-55 187.5 0.0 4.7e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 CDJ93270.1 - 0.00069 19.4 0.0 0.0024 17.6 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal COPIIcoated_ERV PF07970.12 CDJ93274.1 - 4.7e-32 111.6 0.1 8.1e-32 110.8 0.1 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CDJ93274.1 - 4.9e-31 106.9 1.7 1.4e-30 105.4 0.1 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF3149 PF11346.8 CDJ93275.1 - 0.0073 15.9 0.4 0.011 15.3 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3149) DUF1218 PF06749.12 CDJ93275.1 - 0.011 16.2 0.9 0.017 15.6 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1218) WBP-1 PF11669.8 CDJ93275.1 - 0.022 15.4 1.1 0.033 14.8 1.1 1.3 1 0 0 1 1 1 0 WW domain-binding protein 1 EphA2_TM PF14575.6 CDJ93275.1 - 0.026 15.4 0.0 0.041 14.8 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SieB PF14163.6 CDJ93275.1 - 0.043 13.3 0.2 0.066 12.7 0.2 1.2 1 0 0 1 1 1 0 Super-infection exclusion protein B PRIMA1 PF16101.5 CDJ93275.1 - 0.067 13.2 0.6 0.1 12.6 0.6 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Wzy_C PF04932.15 CDJ93275.1 - 0.084 12.5 0.3 0.37 10.4 0.2 1.8 1 1 0 2 2 2 0 O-Antigen ligase OAD_gamma PF04277.13 CDJ93275.1 - 0.095 13.3 0.1 0.13 12.8 0.1 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain MAP17 PF15807.5 CDJ93275.1 - 0.11 12.7 0.5 0.15 12.3 0.5 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 PufQ PF05398.11 CDJ93275.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 PufQ cytochrome subunit SIT PF15330.6 CDJ93275.1 - 0.12 12.9 0.3 0.18 12.2 0.3 1.3 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT TMEM132D_C PF15706.5 CDJ93275.1 - 0.14 12.0 0.4 0.24 11.2 0.4 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term LapA_dom PF06305.11 CDJ93275.1 - 0.14 12.0 0.1 0.2 11.5 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain FixH PF05751.11 CDJ93275.1 - 0.22 11.6 1.7 0.34 10.9 1.7 1.3 1 0 0 1 1 1 0 FixH Vpu PF00558.19 CDJ93275.1 - 0.28 11.0 1.4 0.43 10.4 1.4 1.2 1 0 0 1 1 1 0 Vpu protein TarH PF02203.15 CDJ93276.1 - 0.025 14.5 0.1 0.05 13.5 0.1 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue Vma12 PF11712.8 CDJ93276.1 - 0.34 11.0 2.3 0.32 11.1 1.4 1.4 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ASC PF00858.24 CDJ93277.1 - 9.5e-15 54.5 0.5 8.6e-07 28.3 0.2 2.1 1 1 1 2 2 2 2 Amiloride-sensitive sodium channel zf-H2C2_2 PF13465.6 CDJ93278.1 - 1.4e-18 66.4 16.1 3.4e-08 33.5 0.2 4.7 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 CDJ93278.1 - 1e-16 60.4 18.5 6.9e-07 29.4 0.8 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ93278.1 - 2.6e-10 40.2 14.5 0.0036 18.0 2.0 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDJ93278.1 - 0.0034 17.3 6.0 0.38 10.8 0.6 3.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ93278.1 - 0.0061 16.8 1.0 14 6.1 0.0 3.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 CDJ93278.1 - 0.012 15.5 9.2 1.1 9.2 0.5 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zf_RING PF16744.5 CDJ93278.1 - 0.016 15.3 0.9 1 9.5 0.1 2.4 1 1 1 2 2 2 0 KIAA1045 RING finger zf-met PF12874.7 CDJ93278.1 - 0.061 13.7 4.2 9.7 6.7 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Ogr_Delta PF04606.12 CDJ93278.1 - 0.12 12.4 0.2 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-BED PF02892.15 CDJ93278.1 - 0.19 11.8 4.2 2 8.5 4.1 2.5 1 1 0 1 1 1 0 BED zinc finger C1_2 PF03107.16 CDJ93278.1 - 2.6 8.5 5.7 13 6.2 1.9 3.3 2 1 0 2 2 2 0 C1 domain zf-C2H2_11 PF16622.5 CDJ93278.1 - 3.8 7.4 7.6 36 4.2 0.1 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-UBR PF02207.20 CDJ93278.1 - 7.9 6.7 8.1 1.6 8.9 3.6 2.2 2 1 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) DPPIV_N PF00930.21 CDJ93279.1 - 1.1e-61 208.6 1.0 1.4e-61 208.2 1.0 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 CDJ93279.1 - 3.5e-44 150.8 0.2 8.1e-44 149.6 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 CDJ93279.1 - 1.6e-05 24.8 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 CDJ93279.1 - 6.1e-05 22.7 0.1 0.00035 20.3 0.0 1.9 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 CDJ93279.1 - 9.1e-05 21.8 0.1 0.061 12.6 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 CDJ93279.1 - 9.4e-05 22.1 0.1 0.00034 20.2 0.1 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 CDJ93279.1 - 0.00013 21.9 0.0 0.00046 20.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2920 PF11144.8 CDJ93279.1 - 0.00021 20.6 0.3 0.0013 18.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2920) Abhydrolase_6 PF12697.7 CDJ93279.1 - 0.0016 19.1 0.0 0.0098 16.5 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDJ93279.1 - 0.014 15.1 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S28 PF05577.12 CDJ93279.1 - 0.019 13.7 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 AXE1 PF05448.12 CDJ93279.1 - 0.05 12.3 0.1 0.11 11.2 0.0 1.5 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 CDJ93279.1 - 0.099 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PDZ PF00595.24 CDJ93282.1 - 3.6e-26 91.3 0.1 2.3e-09 37.5 0.0 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 CDJ93282.1 - 1.7e-15 56.6 0.3 3.8e-07 29.8 0.0 3.6 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 CDJ93282.1 - 2.2e-10 40.7 0.7 0.00038 20.7 0.0 3.5 3 0 0 3 3 3 3 PDZ domain U1snRNP70_N PF12220.8 CDJ93282.1 - 0.026 15.1 3.1 0.23 12.1 3.1 2.7 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Dus PF01207.17 CDJ93285.1 - 8.9e-66 222.1 0.6 8.9e-66 222.1 0.6 1.8 3 0 0 3 3 3 1 Dihydrouridine synthase (Dus) Proteasome PF00227.26 CDJ93285.1 - 6.9e-23 81.1 0.3 1.1e-22 80.4 0.3 1.3 1 0 0 1 1 1 1 Proteasome subunit BKACE PF05853.12 CDJ93285.1 - 0.01 15.2 0.5 0.026 13.8 0.1 1.9 2 0 0 2 2 2 0 beta-keto acid cleavage enzyme NMO PF03060.15 CDJ93285.1 - 0.031 13.7 0.1 0.056 12.8 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase ThiG PF05690.14 CDJ93285.1 - 0.037 13.3 0.4 0.074 12.3 0.1 1.6 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF2656 PF10847.8 CDJ93285.1 - 0.048 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2656) Toprim_C_rpt PF13368.6 CDJ93285.1 - 0.068 13.2 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat IMPDH PF00478.25 CDJ93285.1 - 0.14 11.1 0.4 0.24 10.4 0.4 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain TPR_1 PF00515.28 CDJ93286.1 - 1.3e-14 53.3 0.1 7.7e-07 28.7 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ93286.1 - 1.3e-12 46.8 0.3 2.5e-05 24.0 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ93286.1 - 9.7e-08 31.5 1.6 0.0008 19.3 0.1 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ93286.1 - 1.2e-06 28.6 0.5 1.2e-06 28.6 0.5 1.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ93286.1 - 1.4e-05 25.5 3.0 0.00041 20.9 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ93286.1 - 1.4e-05 25.3 3.5 1.6e-05 25.1 1.6 2.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ93286.1 - 2.8e-05 24.5 1.0 0.0028 18.1 0.2 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ93286.1 - 4.2e-05 23.6 0.6 0.15 12.5 0.1 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ93286.1 - 0.00011 22.1 0.1 0.0013 18.7 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ93286.1 - 0.00068 20.2 1.8 0.0049 17.5 0.2 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ93286.1 - 0.0018 18.8 0.7 0.088 13.5 0.1 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 CDJ93286.1 - 0.0023 17.2 0.1 0.0032 16.7 0.1 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF3856 PF12968.7 CDJ93286.1 - 0.0057 16.7 0.4 0.05 13.7 0.4 2.0 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_11 PF13414.6 CDJ93286.1 - 0.017 14.8 0.0 0.15 11.8 0.0 2.3 1 1 2 3 3 3 0 TPR repeat Clathrin PF00637.20 CDJ93286.1 - 0.02 14.8 0.1 0.44 10.4 0.0 2.1 1 1 1 2 2 2 0 Region in Clathrin and VPS ANAPC3 PF12895.7 CDJ93286.1 - 0.088 13.0 1.4 0.2 11.9 1.4 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 CDJ93286.1 - 0.22 11.9 0.4 24 5.5 0.0 2.7 3 0 0 3 3 2 0 PPR repeat Prominin PF05478.11 CDJ93288.1 - 0.026 12.5 0.1 0.042 11.8 0.1 1.3 1 0 0 1 1 1 0 Prominin DUF2561 PF10812.8 CDJ93288.1 - 0.045 13.8 0.0 0.045 13.8 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2561) RIFIN PF02009.16 CDJ93288.1 - 0.082 12.8 10.9 0.21 11.5 10.9 1.5 1 1 1 2 2 2 0 Rifin DUF4064 PF13273.6 CDJ93288.1 - 0.14 12.5 7.1 1.4 9.2 7.0 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Hamartin PF04388.12 CDJ93288.1 - 0.79 8.3 13.7 0.82 8.3 13.7 1.1 1 0 0 1 1 1 0 Hamartin protein DUF4834 PF16118.5 CDJ93288.1 - 0.98 10.4 0.0 0.98 10.4 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) TMEM154 PF15102.6 CDJ93289.1 - 0.0032 17.4 8.4 0.0032 17.4 8.4 5.3 1 1 3 4 4 4 1 TMEM154 protein family DUF4834 PF16118.5 CDJ93289.1 - 0.0033 18.4 0.3 0.0033 18.4 0.3 4.8 3 1 0 3 3 3 1 Domain of unknown function (DUF4834) SpoIIIAH PF12685.7 CDJ93289.1 - 0.0039 17.1 2.2 0.0039 17.1 2.2 3.4 2 1 1 3 3 3 1 SpoIIIAH-like protein MAP17 PF15807.5 CDJ93289.1 - 0.0098 16.1 0.1 0.0098 16.1 0.1 3.2 2 1 0 2 2 2 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 EphA2_TM PF14575.6 CDJ93289.1 - 0.026 15.4 0.0 0.11 13.4 0.0 2.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4176 PF13780.6 CDJ93289.1 - 0.043 13.9 0.2 0.11 12.5 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) Peptidase_S49_N PF08496.10 CDJ93289.1 - 0.053 13.6 0.2 0.13 12.3 0.2 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FixQ PF05545.11 CDJ93289.1 - 0.13 12.3 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Filo_VP35 PF02097.15 CDJ93290.1 - 0.19 10.7 0.0 0.23 10.5 0.0 1.0 1 0 0 1 1 1 0 Filoviridae VP35 EphA2_TM PF14575.6 CDJ93291.1 - 0.0015 19.3 1.4 0.0036 18.2 1.4 1.8 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain V_ATPase_I PF01496.19 CDJ93291.1 - 0.0031 15.5 0.1 0.0037 15.3 0.1 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Connexin PF00029.19 CDJ93291.1 - 0.0032 17.3 4.4 0.019 14.7 4.4 1.9 1 1 0 1 1 1 1 Connexin 7TM_GPCR_Srv PF10323.9 CDJ93291.1 - 0.0034 16.8 0.0 0.0043 16.5 0.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv TMEM51 PF15345.6 CDJ93291.1 - 0.0054 16.6 4.1 0.013 15.4 4.1 1.6 1 1 0 1 1 1 1 Transmembrane protein 51 Zip PF02535.22 CDJ93291.1 - 0.0056 15.9 0.1 0.0069 15.7 0.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Tmemb_9 PF05434.11 CDJ93291.1 - 0.0057 16.6 0.5 0.011 15.6 0.0 1.5 1 1 1 2 2 2 1 TMEM9 MFS_1 PF07690.16 CDJ93291.1 - 0.0064 15.5 0.0 0.0068 15.4 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily BatD PF13584.6 CDJ93291.1 - 0.009 14.9 0.3 0.011 14.6 0.1 1.3 1 1 0 1 1 1 1 Oxygen tolerance Insulin_TMD PF17870.1 CDJ93291.1 - 0.013 15.6 0.8 0.026 14.6 0.8 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4381 PF14316.6 CDJ93291.1 - 0.016 15.5 0.0 0.022 15.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Syndecan PF01034.20 CDJ93291.1 - 0.022 14.7 4.5 0.048 13.6 0.1 2.2 2 0 0 2 2 2 0 Syndecan domain SCIMP PF15050.6 CDJ93291.1 - 0.022 15.2 0.4 0.041 14.3 0.1 1.5 1 1 0 1 1 1 0 SCIMP protein UPF0242 PF06785.11 CDJ93291.1 - 0.022 14.9 0.5 0.026 14.6 0.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4064 PF13273.6 CDJ93291.1 - 0.028 14.7 0.0 0.046 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) FAM176 PF14851.6 CDJ93291.1 - 0.03 14.0 0.4 0.03 14.0 0.4 2.0 1 1 1 2 2 2 0 FAM176 family Conotoxin PF02950.17 CDJ93291.1 - 0.035 15.1 2.4 0.036 15.1 0.2 2.0 1 1 1 2 2 2 0 Conotoxin GAPT PF11770.8 CDJ93291.1 - 0.035 14.0 0.2 0.049 13.5 0.2 1.3 1 1 0 1 1 1 0 GRB2-binding adapter (GAPT) DUF4834 PF16118.5 CDJ93291.1 - 0.053 14.5 6.2 0.45 11.5 6.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) OAD_gamma PF04277.13 CDJ93291.1 - 0.064 13.8 3.3 0.22 12.1 3.3 1.9 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain SID-1_RNA_chan PF13965.6 CDJ93291.1 - 0.081 11.3 0.0 0.085 11.3 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TMEM154 PF15102.6 CDJ93291.1 - 0.083 12.8 1.6 0.11 12.4 0.2 1.8 1 1 1 2 2 2 0 TMEM154 protein family SIT PF15330.6 CDJ93291.1 - 0.086 13.3 1.5 0.16 12.4 1.5 1.6 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Nucleoside_tran PF01733.18 CDJ93291.1 - 0.095 12.1 0.6 0.14 11.5 0.6 1.5 1 1 0 1 1 1 0 Nucleoside transporter DUF2561 PF10812.8 CDJ93291.1 - 0.12 12.3 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Wzy_C PF04932.15 CDJ93291.1 - 0.17 11.5 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 O-Antigen ligase FeoB_associated PF12669.7 CDJ93291.1 - 0.2 12.1 1.4 0.77 10.2 1.4 2.0 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Ctr PF04145.15 CDJ93291.1 - 0.22 12.2 0.8 0.33 11.6 0.8 1.4 1 1 0 1 1 1 0 Ctr copper transporter family MTABC_N PF16185.5 CDJ93291.1 - 0.25 10.8 0.0 0.25 10.8 0.0 1.4 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region Herpes_LMP1 PF05297.11 CDJ93291.1 - 0.29 10.3 0.0 0.32 10.2 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) OATP PF03137.20 CDJ93291.1 - 0.3 9.3 0.0 0.33 9.2 0.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Orf78 PF06024.12 CDJ93291.1 - 0.82 10.0 6.7 0.12 12.7 0.9 2.3 1 1 1 2 2 2 0 Orf78 (ac78) XRN_M PF17846.1 CDJ93291.1 - 0.92 8.4 5.9 1 8.3 5.9 1.0 1 0 0 1 1 1 0 Xrn1 helical domain MAP17 PF15807.5 CDJ93291.1 - 2.9 8.1 8.5 13 6.0 8.5 1.9 1 1 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF2149 PF09919.9 CDJ93291.1 - 6.9 7.0 9.1 3.2e+02 1.7 9.1 2.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) adh_short_C2 PF13561.6 CDJ93292.1 - 8e-57 192.5 0.0 9.9e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDJ93292.1 - 7.5e-49 165.8 0.1 8.8e-49 165.6 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDJ93292.1 - 6.6e-11 42.4 0.0 9.5e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 KR domain AlaDh_PNT_C PF01262.21 CDJ93292.1 - 0.066 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short_C2 PF13561.6 CDJ93293.1 - 7.3e-63 212.2 0.3 9e-63 211.9 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDJ93293.1 - 4.2e-53 179.7 0.5 4.9e-53 179.5 0.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDJ93293.1 - 3.3e-12 46.7 0.1 4.4e-12 46.3 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDJ93293.1 - 3.8e-05 23.3 0.1 7.4e-05 22.3 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family LIM PF00412.22 CDJ93294.1 - 3.3e-22 78.5 19.7 8.5e-12 45.1 10.3 2.2 2 0 0 2 2 2 2 LIM domain zf-C3HC4_3 PF13920.6 CDJ93294.1 - 0.007 16.2 3.6 0.007 16.2 3.6 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf_UBZ PF18439.1 CDJ93294.1 - 2.3 7.9 17.3 0.51 10.0 0.7 4.3 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger UPF1_Zn_bind PF09416.10 CDJ93296.1 - 1.2e-65 220.2 8.8 5.5e-65 218.0 6.7 2.4 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 CDJ93296.1 - 1.5e-60 204.3 0.0 3.3e-60 203.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ93296.1 - 4.8e-44 151.1 7.2 1.1e-23 84.4 2.9 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 CDJ93296.1 - 3.8e-30 104.0 0.0 8.1e-30 102.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 CDJ93296.1 - 1e-14 54.7 0.3 6.9e-14 52.0 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ93296.1 - 6.2e-12 46.1 0.6 1.7e-11 44.7 0.6 1.7 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CDJ93296.1 - 8.6e-06 25.7 0.1 0.18 11.5 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 CDJ93296.1 - 3.3e-05 23.9 0.0 6.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CDJ93296.1 - 4.2e-05 22.9 0.3 0.00093 18.5 0.1 2.6 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 CDJ93296.1 - 8e-05 22.6 0.6 0.00032 20.6 0.6 2.0 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 CDJ93296.1 - 8.8e-05 22.2 0.1 0.015 14.9 0.1 2.3 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain Herpes_ori_bp PF02399.15 CDJ93296.1 - 0.00031 18.9 0.0 0.00048 18.3 0.0 1.2 1 0 0 1 1 1 1 Origin of replication binding protein AAA_16 PF13191.6 CDJ93296.1 - 0.0038 17.6 1.0 0.0093 16.4 0.2 2.0 2 0 0 2 2 2 1 AAA ATPase domain DEAD PF00270.29 CDJ93296.1 - 0.0074 16.1 0.8 0.015 15.0 0.8 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase ATPase PF06745.13 CDJ93296.1 - 0.0099 15.2 0.0 0.052 12.9 0.0 2.0 2 0 0 2 2 2 1 KaiC SRP54 PF00448.22 CDJ93296.1 - 0.019 14.6 0.1 0.039 13.6 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PhoH PF02562.16 CDJ93296.1 - 0.025 14.1 0.2 0.051 13.0 0.0 1.5 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 CDJ93296.1 - 0.035 14.4 0.1 0.23 11.7 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.7 CDJ93296.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Methyltr_RsmB-F PF01189.17 CDJ93297.1 - 2.7e-38 131.6 0.0 3.6e-37 128.0 0.0 2.3 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CDJ93297.1 - 0.0018 18.4 0.0 0.0039 17.3 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase RCC1 PF00415.18 CDJ93298.1 - 4.3e-68 225.7 18.3 8.2e-12 45.6 0.1 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ93298.1 - 3e-43 144.8 26.8 1.5e-09 37.4 0.0 8.0 8 1 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Kelch_2 PF07646.15 CDJ93298.1 - 0.019 15.0 3.0 35 4.6 0.2 4.1 4 0 0 4 4 4 0 Kelch motif zf-C2H2 PF00096.26 CDJ93299.1 - 1.3 9.6 15.8 0.79 10.3 0.4 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type PBP1_TM PF14812.6 CDJ93300.1 - 5.3 7.5 9.8 1 9.8 0.1 2.6 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FGGY_C PF02782.16 CDJ93301.1 - 9.1e-08 32.1 0.0 1.3e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Kelch_4 PF13418.6 CDJ93301.1 - 0.17 11.9 0.1 0.52 10.4 0.1 1.8 1 1 0 1 1 1 0 Galactose oxidase, central domain SCVP PF17619.2 CDJ93302.1 - 6.6e-16 58.9 0.0 8.8e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Secreted clade V proteins ANAPC5 PF12862.7 CDJ93303.1 - 3.9e-09 36.4 2.2 2.9e-08 33.6 0.4 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_14 PF13428.6 CDJ93303.1 - 0.1 13.5 11.3 1.8 9.6 0.1 5.7 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ93303.1 - 2 9.0 7.5 7.1 7.2 0.1 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 CDJ93304.1 - 0.006 16.3 0.1 0.0098 15.6 0.1 1.5 1 1 0 1 1 1 1 26S proteasome subunit RPN7 TPR_8 PF13181.6 CDJ93304.1 - 0.072 13.3 0.8 4.5 7.7 0.2 3.2 2 1 2 4 4 4 0 Tetratricopeptide repeat DUF2225 PF09986.9 CDJ93304.1 - 0.078 12.7 0.1 0.097 12.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Actin PF00022.19 CDJ93305.1 - 1.7e-80 270.7 0.0 8.1e-79 265.1 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CDJ93305.1 - 0.00036 19.5 0.0 0.29 9.9 0.0 2.6 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CDJ93305.1 - 0.019 15.4 0.0 0.044 14.2 0.0 1.7 2 1 0 2 2 2 0 Cell division protein FtsA Topoisom_I PF01028.20 CDJ93306.1 - 8.8e-100 332.7 6.3 8.8e-100 332.7 6.3 2.5 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 CDJ93306.1 - 2.2e-96 321.4 2.6 2.2e-96 321.4 2.6 4.0 3 1 1 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 CDJ93306.1 - 3.1e-32 110.3 0.9 3.1e-32 110.3 0.9 2.8 2 0 0 2 2 2 1 C-terminal topoisomerase domain WD40 PF00400.32 CDJ93308.1 - 5.1e-07 30.3 10.8 0.055 14.4 0.6 7.1 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ93308.1 - 9.2e-05 22.7 0.0 0.014 15.7 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Dynein_IC2 PF11540.8 CDJ93308.1 - 0.015 15.2 0.1 0.042 13.8 0.1 1.7 1 0 0 1 1 1 0 Cytoplasmic dynein 1 intermediate chain 2 PQQ_3 PF13570.6 CDJ93308.1 - 0.016 15.7 0.0 1.8 9.1 0.0 3.3 2 0 0 2 2 2 0 PQQ-like domain Frtz PF11768.8 CDJ93308.1 - 0.19 10.0 0.1 0.69 8.2 0.0 1.8 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF267 PF03268.14 CDJ93309.1 - 1.4e-64 218.3 2.0 1.6e-64 218.1 2.0 1.0 1 0 0 1 1 1 1 Caenorhabditis protein of unknown function, DUF267 7tm_7 PF08395.12 CDJ93309.1 - 6.7e-06 25.5 12.5 1.6e-05 24.3 12.3 1.6 1 1 0 1 1 1 1 7tm Chemosensory receptor DUF267 PF03268.14 CDJ93310.1 - 4.2e-63 213.4 9.0 4.8e-63 213.2 9.0 1.0 1 0 0 1 1 1 1 Caenorhabditis protein of unknown function, DUF267 CAP PF00188.26 CDJ93311.1 - 1.6e-39 135.6 26.5 7.1e-17 62.4 6.6 3.4 3 0 0 3 3 3 3 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ93311.1 - 0.12 12.7 18.0 0.28 11.5 2.3 3.9 5 1 0 5 5 5 0 Ancylostoma-associated secreted protein related Mucin PF01456.17 CDJ93311.1 - 0.31 11.0 33.3 0.58 10.1 22.6 2.7 2 0 0 2 2 2 0 Mucin-like glycoprotein Metallothio_Euk PF12749.7 CDJ93311.1 - 2 8.6 33.6 2 8.6 7.6 3.8 3 0 0 3 3 3 0 Eukaryotic metallothionein SLC12 PF03522.15 CDJ93313.1 - 2.1e-142 475.2 0.0 3.6e-142 474.4 0.0 1.4 1 0 0 1 1 1 1 Solute carrier family 12 AA_permease PF00324.21 CDJ93313.1 - 4.9e-109 365.1 32.2 6.1e-109 364.7 32.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_N PF08403.10 CDJ93313.1 - 0.00042 19.8 0.0 0.047 13.2 0.0 2.7 2 0 0 2 2 2 2 Amino acid permease N-terminal dCMP_cyt_deam_1 PF00383.23 CDJ93315.1 - 3.3e-20 71.8 0.0 5.1e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 CDJ93315.1 - 9.8e-11 42.0 0.3 3.1e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 CDJ93315.1 - 7.7e-05 22.4 2.4 0.0014 18.2 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases CNH PF00780.22 CDJ93316.1 - 1.6e-40 139.5 0.0 3.2e-40 138.5 0.0 1.5 1 1 0 1 1 1 1 CNH domain PH PF00169.29 CDJ93316.1 - 2e-09 37.9 0.1 6.5e-09 36.2 0.0 1.9 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 CDJ93316.1 - 0.057 13.8 0.1 0.14 12.6 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain ATP-sulfurylase PF01747.17 CDJ93317.1 - 2.8e-66 223.0 0.0 4e-66 222.5 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 CDJ93317.1 - 2e-55 187.0 0.0 3e-55 186.4 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 CDJ93317.1 - 2.5e-39 134.5 0.0 8.6e-39 132.8 0.0 1.8 2 0 0 2 2 2 1 PUA-like domain CTP_transf_like PF01467.26 CDJ93317.1 - 0.061 13.5 0.1 10 6.3 0.0 2.6 3 0 0 3 3 3 0 Cytidylyltransferase-like G-alpha PF00503.20 CDJ93318.1 - 5.3e-98 328.4 12.0 6.5e-98 328.1 12.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDJ93318.1 - 1.7e-14 53.6 2.2 6.2e-11 42.1 0.2 3.0 2 1 1 3 3 3 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ93318.1 - 0.0017 18.5 0.1 0.82 9.8 0.0 2.8 1 1 1 2 2 2 2 50S ribosome-binding GTPase Roc PF08477.13 CDJ93318.1 - 0.003 17.8 0.5 2.2 8.5 0.0 3.0 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CDJ93318.1 - 0.0082 15.5 4.9 0.066 12.6 0.4 2.6 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region Ras PF00071.22 CDJ93318.1 - 0.017 14.7 0.1 2.3 7.8 0.0 2.7 2 1 0 2 2 2 0 Ras family AAA_24 PF13479.6 CDJ93318.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 CDJ93318.1 - 0.1 12.1 0.0 2.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 CDJ93318.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CCDC66 PF15236.6 CDJ93319.1 - 1e-07 31.9 26.8 2.2e-07 30.8 26.8 1.5 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 66 LMBR1 PF04791.16 CDJ93319.1 - 1.6 7.6 2.6 1.8 7.4 2.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Peptidase_U57 PF05582.12 CDJ93319.1 - 7.9 5.6 5.8 15 4.7 5.8 1.4 1 0 0 1 1 1 0 YabG peptidase U57 zinc_ribbon_10 PF10058.9 CDJ93321.1 - 8.8e-18 63.8 0.5 1.4e-17 63.2 0.5 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein TMEM240 PF15207.6 CDJ93321.1 - 0.19 11.4 0.2 0.32 10.7 0.2 1.3 1 0 0 1 1 1 0 TMEM240 family Glyco_transf_10 PF00852.19 CDJ93323.1 - 4.2e-60 202.5 3.7 5.5e-60 202.1 3.7 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CDJ93323.1 - 3.4e-15 56.5 0.1 1.4e-14 54.4 0.0 1.9 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal WGR PF05406.15 CDJ93323.1 - 0.092 12.8 0.0 15 5.8 0.0 2.6 2 0 0 2 2 2 0 WGR domain SH2 PF00017.24 CDJ93324.1 - 9.2e-15 54.5 0.0 1.9e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 SH2 domain RasGEF PF00617.19 CDJ93324.1 - 6.1e-06 26.6 0.1 1.2e-05 25.6 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain FAD_binding_2 PF00890.24 CDJ93325.1 - 3e-124 415.3 4.2 4.1e-124 414.8 4.2 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 CDJ93325.1 - 8.5e-41 138.9 0.2 1.6e-40 138.0 0.2 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term DHHC PF01529.20 CDJ93325.1 - 1.3e-27 96.5 14.2 1.3e-27 96.5 14.2 2.4 2 0 0 2 2 1 1 DHHC palmitoyltransferase Ank_2 PF12796.7 CDJ93325.1 - 1.9e-26 92.5 0.6 3.2e-09 37.2 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDJ93325.1 - 8.8e-19 65.6 2.4 1.5e-05 25.0 0.2 6.8 6 0 0 6 6 5 3 Ankyrin repeat Ank_4 PF13637.6 CDJ93325.1 - 1.1e-18 67.3 3.4 4.2e-06 27.2 0.0 6.1 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 CDJ93325.1 - 2.8e-17 62.3 0.9 0.0033 17.8 0.1 6.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 CDJ93325.1 - 3.4e-17 62.3 10.3 9.4e-05 22.6 0.2 6.3 3 1 4 7 7 7 4 Ankyrin repeats (many copies) Thi4 PF01946.17 CDJ93325.1 - 9.6e-05 21.7 0.4 0.023 14.0 0.2 2.4 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 CDJ93325.1 - 0.00089 18.6 1.8 0.0054 16.0 0.7 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CDJ93325.1 - 0.0021 17.2 2.8 0.068 12.2 2.2 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 CDJ93325.1 - 0.011 15.0 1.1 0.022 14.0 1.1 1.5 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 CDJ93325.1 - 0.053 12.2 0.9 0.14 10.9 0.9 1.7 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.24 CDJ93325.1 - 0.071 12.7 2.0 0.15 11.6 2.0 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase MnmE_helical PF12631.7 CDJ93325.1 - 0.099 12.8 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 MnmE helical domain FARP PF01581.16 CDJ93326.1 - 0.003 17.7 10.1 2.6 8.9 0.6 3.5 3 0 0 3 3 3 3 FMRFamide related peptide family DUF229 PF02995.17 CDJ93328.1 - 5.6e-48 163.8 0.2 1.9e-47 162.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF229) MtmB PF05369.12 CDJ93328.1 - 0.053 12.3 0.0 0.078 11.8 0.0 1.2 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB Sulfatase PF00884.23 CDJ93328.1 - 0.054 12.9 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 Sulfatase Mob1_phocein PF03637.17 CDJ93329.1 - 2.1e-68 229.6 0.0 2.5e-68 229.4 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family Sec23_trunk PF04811.15 CDJ93330.1 - 1.1e-77 260.9 0.0 1.6e-77 260.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CDJ93330.1 - 7.9e-19 67.4 0.0 1.3e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CDJ93330.1 - 3e-15 56.0 3.2 5.4e-15 55.2 3.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 CDJ93330.1 - 1.1e-13 51.8 0.0 1.9e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 CDJ93330.1 - 2e-08 34.0 0.0 5.1e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat TED_complement PF07678.14 CDJ93331.1 - 1.6e-95 319.8 0.0 8.3e-95 317.4 0.0 1.9 2 0 0 2 2 2 1 A-macroglobulin TED domain A2M PF00207.22 CDJ93331.1 - 1.2e-24 85.9 0.0 4.2e-24 84.2 0.0 2.0 2 0 0 2 2 2 1 Alpha-2-macroglobulin family DUF5006 PF16397.5 CDJ93331.1 - 0.079 12.1 0.0 1.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5006) SWIB PF02201.18 CDJ93332.1 - 1.1e-21 76.5 0.2 2.7e-21 75.2 0.2 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain TTL PF03133.15 CDJ93333.1 - 7.4e-27 94.2 0.0 1.4e-26 93.3 0.0 1.4 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CDJ93333.1 - 0.00013 21.3 0.0 0.00018 20.8 0.0 1.2 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CDJ93333.1 - 0.00044 19.6 0.0 0.00067 19.0 0.0 1.2 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp TAF4 PF05236.14 CDJ93333.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Frag1 PF10277.9 CDJ93334.1 - 0.0011 18.6 12.4 0.0016 18.0 12.4 1.4 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family GWT1 PF06423.12 CDJ93334.1 - 0.0021 18.2 1.2 0.0036 17.4 1.2 1.4 1 0 0 1 1 1 1 GWT1 7tm_1 PF00001.21 CDJ93335.1 - 1.6e-07 30.9 18.0 6.1e-07 29.0 17.8 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1691 PF07950.11 CDJ93335.1 - 0.049 14.4 5.6 0.34 11.6 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1691) Pkinase_Tyr PF07714.17 CDJ93336.1 - 4.7e-73 245.7 0.0 6.2e-73 245.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ93336.1 - 3.5e-45 154.4 0.0 5.1e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ93336.1 - 2.6e-06 27.0 0.0 5.4e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like SH2 PF00017.24 CDJ93336.1 - 0.00011 22.2 0.0 0.00073 19.6 0.0 2.3 1 1 0 1 1 1 1 SH2 domain Kdo PF06293.14 CDJ93336.1 - 0.054 12.8 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Hs1pro-1_C PF07014.12 CDJ93336.1 - 0.074 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus RVT_1 PF00078.27 CDJ93338.1 - 2.4e-07 30.5 0.1 5.6e-07 29.3 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDJ93338.1 - 0.075 13.3 1.3 0.16 12.3 0.4 2.0 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Exo_endo_phos_2 PF14529.6 CDJ93339.1 - 1.6e-06 28.0 0.0 3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF5615 PF18480.1 CDJ93339.1 - 0.082 12.7 0.0 3.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) Ribosomal_S5 PF00333.20 CDJ93339.1 - 0.15 12.1 0.8 0.27 11.3 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein S5, N-terminal domain Sulfatase PF00884.23 CDJ93340.1 - 1.3e-38 133.2 0.0 1.7e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 CDJ93340.1 - 5.7e-24 85.2 0.1 1.2e-23 84.1 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.17 CDJ93340.1 - 0.00049 18.8 0.0 0.00058 18.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 CDJ93340.1 - 0.015 14.9 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase OATP PF03137.20 CDJ93341.1 - 0.22 9.8 4.2 0.23 9.7 4.2 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Sulfatase PF00884.23 CDJ93342.1 - 8.8e-57 192.8 0.0 1.1e-56 192.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 CDJ93342.1 - 2.4e-22 80.0 0.1 5.2e-22 78.9 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.17 CDJ93342.1 - 0.00044 19.0 0.0 0.00055 18.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 CDJ93342.1 - 0.0044 16.6 0.0 0.011 15.4 0.0 1.6 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CDJ93344.1 - 8.9e-75 251.9 0.0 1.2e-74 251.6 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 CDJ93344.1 - 7.7e-23 81.6 0.0 1.5e-22 80.6 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 CDJ93344.1 - 6e-05 22.8 0.1 0.00018 21.2 0.1 1.7 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 CDJ93344.1 - 0.0006 18.6 0.0 0.00083 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) RVT_1 PF00078.27 CDJ93345.1 - 2.2e-39 135.2 0.0 3.7e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DENN PF02141.21 CDJ93348.1 - 8.5e-44 149.7 5.6 1.5e-43 148.9 5.6 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain RUN PF02759.19 CDJ93348.1 - 2.4e-22 79.3 0.0 2.2e-19 69.7 0.0 3.7 3 1 0 3 3 3 2 RUN domain dDENN PF03455.19 CDJ93348.1 - 3.8e-16 58.8 1.1 1.1e-15 57.3 1.1 1.9 1 0 0 1 1 1 1 dDENN domain PLAT PF01477.23 CDJ93348.1 - 2.3e-14 54.0 0.0 4.5e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain uDENN PF03456.18 CDJ93348.1 - 1.1e-06 29.2 0.0 1.7e-05 25.5 0.0 2.9 2 0 0 2 2 2 1 uDENN domain QWRF PF04484.12 CDJ93348.1 - 0.55 9.9 6.9 4 7.1 0.5 3.3 3 0 0 3 3 3 0 QWRF family zf-C2H2 PF00096.26 CDJ93349.1 - 5.9e-14 51.6 56.0 0.0015 18.8 1.4 8.6 8 0 0 8 8 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ93349.1 - 9.5e-12 44.7 57.7 0.0093 16.7 1.1 8.3 8 0 0 8 8 7 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ93349.1 - 1.5e-09 37.9 24.5 0.04 14.2 0.2 6.4 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CDJ93349.1 - 4.4e-06 26.9 55.0 0.0063 16.9 0.1 9.1 8 0 0 8 8 7 5 Zinc-finger double domain zf-C2H2_11 PF16622.5 CDJ93349.1 - 6.4e-05 22.6 12.8 0.00039 20.1 0.1 5.2 4 0 0 4 4 4 1 zinc-finger C2H2-type zf_UBZ PF18439.1 CDJ93349.1 - 0.00043 19.8 19.2 0.36 10.5 0.3 5.7 5 0 0 5 5 5 3 Ubiquitin-Binding Zinc Finger zf_C2H2_ZHX PF18387.1 CDJ93349.1 - 0.0025 17.4 32.6 0.26 10.9 0.2 7.3 4 2 3 7 7 7 3 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 CDJ93349.1 - 0.0037 17.6 18.7 0.48 10.9 0.5 5.3 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CDJ93349.1 - 0.014 15.3 31.2 0.38 10.8 0.3 6.5 6 0 0 6 6 6 0 C2H2-type zinc finger Elf1 PF05129.13 CDJ93349.1 - 5.6 7.1 30.6 0.8 9.8 3.6 5.4 3 1 1 4 4 4 0 Transcription elongation factor Elf1 like ADK_lid PF05191.14 CDJ93349.1 - 7.4 6.7 21.0 0.87 9.6 0.8 5.8 6 0 0 6 6 6 0 Adenylate kinase, active site lid Pkinase PF00069.25 CDJ93350.1 - 1.1e-06 28.3 0.0 1.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ93350.1 - 0.00052 19.4 0.0 0.00067 19.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase tRNA-synt_1d PF00750.19 CDJ93351.1 - 3.9e-64 216.8 0.4 5.7e-64 216.3 0.4 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 CDJ93351.1 - 1.4e-16 60.7 0.1 5.2e-16 58.9 0.0 2.0 2 0 0 2 2 2 1 DALR anticodon binding domain DUF1367 PF07105.11 CDJ93351.1 - 0.017 14.8 0.3 0.071 12.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1367) PhoH PF02562.16 CDJ93351.1 - 0.14 11.6 0.0 0.65 9.4 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein EamA PF00892.20 CDJ93352.1 - 2.7e-15 56.7 14.5 1.7e-08 34.7 0.4 2.7 2 1 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 CDJ93352.1 - 1.8e-12 46.8 0.4 1.8e-12 46.8 0.4 1.9 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 CDJ93352.1 - 1.2e-10 41.4 9.7 4.2e-10 39.6 2.7 2.1 2 0 0 2 2 2 2 Solute carrier family 35 TPT PF03151.16 CDJ93352.1 - 3.4e-10 39.7 1.9 5.3e-10 39.1 1.9 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 CDJ93352.1 - 3.8e-07 29.6 4.7 1.2e-06 27.9 4.7 1.9 1 1 0 1 1 1 1 Nucleotide-sugar transporter Multi_Drug_Res PF00893.19 CDJ93352.1 - 0.92 10.2 7.7 7.6 7.3 0.8 2.8 2 0 0 2 2 2 0 Small Multidrug Resistance protein EamA PF00892.20 CDJ93353.1 - 2e-14 53.9 26.7 1.2e-07 32.0 11.7 3.2 3 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 CDJ93353.1 - 3.5e-10 39.7 7.4 4.8e-10 39.3 7.4 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family SLC35F PF06027.12 CDJ93353.1 - 8.6e-08 32.0 11.7 4.8e-06 26.3 4.7 2.2 2 0 0 2 2 2 2 Solute carrier family 35 CRT-like PF08627.10 CDJ93353.1 - 2.3e-07 30.1 9.0 2.3e-07 30.1 9.0 2.3 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 CDJ93353.1 - 0.00011 21.5 12.3 0.00023 20.5 12.3 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 CDJ93353.1 - 0.0014 17.9 8.9 0.0014 17.9 8.9 2.1 1 1 1 2 2 2 1 UAA transporter family Multi_Drug_Res PF00893.19 CDJ93353.1 - 1.4 9.7 8.8 3.9 8.2 1.5 3.0 2 0 0 2 2 2 0 Small Multidrug Resistance protein DUF2070 PF09843.9 CDJ93353.1 - 6.5 4.9 13.4 0.21 9.8 1.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) EF-hand_1 PF00036.32 CDJ93354.1 - 6.3e-14 50.4 0.9 8.8e-07 28.0 0.1 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CDJ93354.1 - 2e-12 46.0 3.1 5.6e-05 22.7 0.2 4.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 CDJ93354.1 - 4e-12 46.4 2.6 8.6e-06 26.1 0.1 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ93354.1 - 1.3e-09 37.7 1.0 0.002 17.9 0.3 4.4 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ93354.1 - 1.2e-05 24.5 1.1 0.005 16.3 0.2 2.7 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 CDJ93354.1 - 2.7e-05 24.4 0.1 0.0016 18.7 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_2 PF09068.11 CDJ93354.1 - 0.0099 16.0 0.0 8.1 6.6 0.0 2.7 2 1 0 2 2 2 2 EF hand EF-hand_14 PF17959.1 CDJ93354.1 - 0.048 14.0 0.6 13 6.2 0.0 3.2 3 1 0 3 3 3 0 EF-hand domain EF-hand_11 PF08976.11 CDJ93354.1 - 0.055 14.3 0.4 0.9 10.5 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Motile_Sperm PF00635.26 CDJ93356.1 - 2.6e-06 27.2 0.0 3.4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Big_2 PF02368.18 CDJ93356.1 - 0.028 14.3 0.0 2.6 8.0 0.0 2.2 1 1 1 2 2 2 0 Bacterial Ig-like domain (group 2) zf-C6H2 PF15801.5 CDJ93358.1 - 3.7 7.9 5.9 0.39 11.1 1.1 1.8 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Peptidase_M13_N PF05649.13 CDJ93359.1 - 2.9e-87 293.8 5.2 2.9e-87 293.8 5.2 2.0 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.21 CDJ93359.1 - 5.8e-63 212.2 0.0 1.6e-62 210.8 0.0 1.8 1 1 1 2 2 2 1 Peptidase family M13 RVT_1 PF00078.27 CDJ93360.1 - 2.2e-15 56.8 0.0 4.4e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) tRNA_anti-like PF12869.7 CDJ93361.1 - 0.01 15.5 0.2 0.024 14.2 0.2 1.6 1 0 0 1 1 1 0 tRNA_anti-like Protocadherin PF08374.11 CDJ93361.1 - 0.013 15.5 3.0 0.026 14.5 3.0 1.5 1 1 0 1 1 1 0 Protocadherin MAS20 PF02064.15 CDJ93361.1 - 0.031 14.4 2.0 0.031 14.4 2.0 1.8 2 0 0 2 2 2 0 MAS20 protein import receptor BT1 PF03092.16 CDJ93361.1 - 0.04 12.2 0.1 0.047 11.9 0.1 1.1 1 0 0 1 1 1 0 BT1 family DUF5305 PF17231.2 CDJ93361.1 - 0.079 12.3 0.2 0.16 11.4 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Connexin PF00029.19 CDJ93361.1 - 0.094 12.5 0.2 0.22 11.3 0.2 1.6 1 0 0 1 1 1 0 Connexin EMC3_TMCO1 PF01956.16 CDJ93361.1 - 0.26 11.0 1.2 0.68 9.6 1.2 1.6 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF842 PF05811.13 CDJ93362.1 - 0.044 13.5 0.4 0.097 12.4 0.3 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) An_peroxidase PF03098.15 CDJ93363.1 - 4.3e-194 646.0 0.0 5.4e-194 645.7 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase I-set PF07679.16 CDJ93363.1 - 9.3e-40 134.6 0.0 5.4e-19 68.1 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ93363.1 - 3.4e-36 123.7 0.3 7e-16 58.6 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain LRR_8 PF13855.6 CDJ93363.1 - 3e-19 68.5 9.5 8.4e-11 41.5 1.0 2.5 2 0 0 2 2 2 2 Leucine rich repeat ig PF00047.25 CDJ93363.1 - 8e-19 67.6 0.0 2.8e-10 40.2 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 CDJ93363.1 - 1.4e-18 67.0 0.0 5.5e-08 33.0 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain LRR_4 PF12799.7 CDJ93363.1 - 2.2e-10 40.6 13.1 0.0009 19.6 0.8 4.4 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRRNT PF01462.18 CDJ93363.1 - 7.1e-09 35.1 2.6 7.1e-09 35.1 2.6 3.1 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain V-set PF07686.17 CDJ93363.1 - 2.6e-08 34.0 0.3 0.00021 21.4 0.1 4.1 2 2 1 3 3 3 1 Immunoglobulin V-set domain LRR_6 PF13516.6 CDJ93363.1 - 4.2e-06 26.4 1.7 0.2 11.8 0.0 5.2 4 0 0 4 4 4 1 Leucine Rich repeat Ig_6 PF18452.1 CDJ93363.1 - 0.00045 19.7 0.0 1.3 8.7 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 CDJ93363.1 - 0.0016 18.5 0.0 0.29 11.2 0.0 3.0 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain LRR_9 PF14580.6 CDJ93363.1 - 0.0019 17.7 6.1 0.024 14.1 0.4 2.6 2 1 1 3 3 3 2 Leucine-rich repeat Adeno_E3_CR1 PF02440.15 CDJ93363.1 - 0.058 13.2 0.0 0.45 10.3 0.0 2.5 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 LRR_5 PF13306.6 CDJ93363.1 - 0.096 12.6 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 CDJ93363.1 - 0.34 11.6 5.5 1.1e+02 4.0 0.0 5.5 5 0 0 5 5 4 0 Leucine Rich Repeat Ground-like PF04155.18 CDJ93367.1 - 6.6e-18 65.1 0.0 8.1e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Ground-like domain FOLN PF09289.10 CDJ93367.1 - 0.85 9.9 4.8 0.58 10.4 1.5 2.1 2 0 0 2 2 2 0 Follistatin/Osteonectin-like EGF domain DUF5352 PF17303.2 CDJ93368.1 - 4.3e-55 186.1 0.3 4.9e-55 185.9 0.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5352) SMK-1 PF04802.15 CDJ93369.1 - 8.9e-64 214.9 1.7 1.8e-63 213.9 1.7 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 HEAT_2 PF13646.6 CDJ93369.1 - 0.096 13.1 0.7 0.43 11.0 0.0 2.4 3 0 0 3 3 3 0 HEAT repeats SAPS PF04499.15 CDJ93369.1 - 0.37 9.5 4.7 0.86 8.3 0.0 2.7 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Asp PF00026.23 CDJ93374.1 - 1.2e-69 235.2 0.0 1.4e-69 235.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ93374.1 - 6.9e-11 42.7 0.5 6.3e-09 36.3 0.5 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ93374.1 - 1.1e-05 25.3 0.0 4.1e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal PAM2 PF07145.15 CDJ93375.1 - 0.0046 16.6 0.6 0.0046 16.6 0.6 1.9 2 0 0 2 2 2 1 Ataxin-2 C-terminal region F-box PF00646.33 CDJ93376.1 - 5.3e-07 29.4 0.7 2.1e-06 27.4 0.2 2.2 1 1 1 2 2 2 1 F-box domain F-box-like PF12937.7 CDJ93376.1 - 1.3e-05 25.0 2.2 3e-05 23.8 0.5 2.4 2 0 0 2 2 2 1 F-box-like Kunitz_BPTI PF00014.23 CDJ93378.1 - 1.9e-13 50.4 5.0 1.9e-13 50.4 5.0 2.5 2 1 0 2 2 2 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Lustrin_cystein PF14625.6 CDJ93378.1 - 0.024 15.0 24.9 0.035 14.5 6.9 3.4 2 1 2 4 4 4 0 Lustrin, cysteine-rich repeated domain EB PF01683.18 CDJ93379.1 - 0.0045 17.3 9.7 0.0045 17.3 9.7 5.0 3 2 1 4 4 4 2 EB module Pkinase PF00069.25 CDJ93381.1 - 3.3e-18 66.0 0.0 4.4e-11 42.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain MIT PF04212.18 CDJ93381.1 - 9.9e-12 44.8 2.6 2.3e-11 43.6 2.6 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain PX PF00787.24 CDJ93381.1 - 9.7e-06 25.6 0.0 1.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 PX domain Pkinase_Tyr PF07714.17 CDJ93381.1 - 0.0029 16.9 0.0 0.016 14.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase SRP68 PF16969.5 CDJ93382.1 - 1.2e-90 305.2 17.5 2.1e-89 301.0 17.5 2.3 1 1 0 1 1 1 1 RNA-binding signal recognition particle 68 BRO1 PF03097.18 CDJ93382.1 - 5.7e-07 28.7 5.4 1.3e-06 27.5 3.9 2.1 1 1 1 2 2 2 1 BRO1-like domain TPR_10 PF13374.6 CDJ93382.1 - 1.2e-05 25.0 6.5 0.019 14.8 1.1 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ93382.1 - 9.9e-05 22.6 11.1 0.0088 16.3 1.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF848 PF05852.11 CDJ93382.1 - 0.00072 19.7 9.4 0.43 10.7 5.2 3.5 2 2 0 2 2 2 2 Gammaherpesvirus protein of unknown function (DUF848) TPR_2 PF07719.17 CDJ93382.1 - 0.0025 17.8 13.4 0.059 13.5 3.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ93382.1 - 0.0044 16.8 0.5 0.3 11.0 1.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ93382.1 - 0.023 14.7 6.7 0.087 12.9 0.2 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ93382.1 - 0.52 11.0 21.5 2.7 8.7 0.9 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat Flagellin_N PF00669.20 CDJ93382.1 - 0.53 10.4 4.2 0.45 10.6 0.4 2.5 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region SRP_TPR_like PF17004.5 CDJ93382.1 - 2.2 8.3 7.5 0.99 9.5 0.1 3.5 3 2 0 3 3 3 0 Putative TPR-like repeat PH_14 PF17787.1 CDJ93384.1 - 0.012 15.4 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 PH domain Transposase_1 PF01359.18 CDJ93386.1 - 2.1e-23 81.9 0.5 2.1e-23 81.9 0.5 1.8 2 0 0 2 2 2 1 Transposase (partial DDE domain) DDE_3 PF13358.6 CDJ93386.1 - 2.9e-06 27.1 0.0 5.5e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease Arrestin_C PF02752.22 CDJ93387.1 - 4.9e-08 33.5 0.4 7.8e-08 32.9 0.4 1.2 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Galactosyl_T PF01762.21 CDJ93388.1 - 6.2e-19 68.6 0.1 6.6e-19 68.5 0.1 1.0 1 0 0 1 1 1 1 Galactosyltransferase UMPH-1 PF05822.12 CDJ93388.1 - 0.024 14.1 0.1 0.028 13.9 0.1 1.0 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) ADIP PF11559.8 CDJ93389.1 - 0.036 14.2 0.1 0.053 13.6 0.1 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Hamartin PF04388.12 CDJ93389.1 - 4.6 5.8 10.8 0.077 11.7 1.7 1.9 1 1 0 2 2 2 0 Hamartin protein tRNA_anti-codon PF01336.25 CDJ93390.1 - 2.4e-07 30.7 0.0 3.9e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Adenylate_cycl PF01295.18 CDJ93391.1 - 0.072 11.7 0.2 0.12 10.9 0.1 1.4 1 1 0 1 1 1 0 Adenylate cyclase, class-I tRNA-synt_2 PF00152.20 CDJ93392.1 - 1.7e-81 273.8 0.0 2e-81 273.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 CDJ93392.1 - 0.022 14.7 0.0 0.081 12.9 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) RVT_1 PF00078.27 CDJ93393.1 - 6.8e-05 22.5 0.0 7.5e-05 22.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DAO PF01266.24 CDJ93394.1 - 9.5e-28 97.8 0.1 1.1e-27 97.5 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase I-set PF07679.16 CDJ93395.1 - 2e-26 91.9 0.0 7.2e-14 51.6 0.0 3.0 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ93395.1 - 1.4e-19 70.5 0.0 1.5e-10 41.5 0.0 3.8 4 0 0 4 4 4 2 Immunoglobulin domain Ig_2 PF13895.6 CDJ93395.1 - 3.6e-07 30.4 0.0 0.0019 18.5 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 CDJ93395.1 - 5.4e-06 26.5 3.8 0.0063 16.7 0.0 3.9 3 0 0 3 3 3 2 Immunoglobulin domain Tho2 PF11262.8 CDJ93395.1 - 7.5 5.7 9.4 4 6.6 7.2 1.6 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 LAP1C PF05609.12 CDJ93396.1 - 0.5 9.4 8.2 0.67 9.0 8.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) HGD-D PF06050.13 CDJ93396.1 - 2.5 7.8 7.5 3.7 7.2 7.4 1.3 1 1 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component ALMT PF11744.8 CDJ93396.1 - 3.4 6.4 7.3 4.1 6.1 7.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter UPF0449 PF15136.6 CDJ93396.1 - 6.9 7.2 11.4 3.1 8.3 4.7 3.1 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 SLC12 PF03522.15 CDJ93396.1 - 7.2 5.5 7.0 9.8 5.1 7.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Ground-like PF04155.18 CDJ93397.1 - 1.6e-15 57.5 0.1 3.8e-15 56.3 0.1 1.7 1 0 0 1 1 1 1 Ground-like domain DUF3364 PF11844.8 CDJ93397.1 - 0.065 13.5 2.7 13 6.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3364) MEKHLA PF08670.11 CDJ93397.1 - 0.14 12.0 0.2 0.25 11.2 0.2 1.4 1 0 0 1 1 1 0 MEKHLA domain MMS19_N PF14500.6 CDJ93398.1 - 5.4e-40 137.6 0.0 1.1e-35 123.4 0.0 2.4 2 0 0 2 2 2 2 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 CDJ93398.1 - 9.2e-06 25.0 0.1 2.3e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 RNAPII transcription regulator C-terminal Amino_oxidase PF01593.24 CDJ93399.1 - 2.9e-68 231.2 0.0 3.4e-68 231.0 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ93399.1 - 1.9e-09 37.6 0.1 4.1e-09 36.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CDJ93399.1 - 0.00077 19.5 0.8 0.092 12.7 0.2 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 CDJ93399.1 - 0.0065 16.1 0.4 0.068 12.7 0.5 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CDJ93399.1 - 0.055 12.7 0.1 0.13 11.5 0.1 1.6 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 CDJ93399.1 - 0.07 12.4 0.1 0.14 11.3 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 CDJ93399.1 - 0.087 13.4 0.3 0.73 10.4 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CDJ93399.1 - 0.16 11.2 0.1 0.29 10.3 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CDJ93399.1 - 0.38 10.0 1.2 3.2 6.9 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Hormone_recep PF00104.30 CDJ93400.1 - 1e-25 90.6 0.7 6.2e-16 58.6 0.0 2.8 3 0 0 3 3 3 2 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 CDJ93400.1 - 9e-25 86.9 12.9 1.7e-24 86.0 12.9 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) GAS PF13851.6 CDJ93401.1 - 0.0056 16.1 6.2 0.0057 16.0 5.0 1.4 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding 4HB_MCP_1 PF12729.7 CDJ93401.1 - 0.011 15.3 3.8 0.015 14.8 3.8 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction ApoLp-III PF07464.11 CDJ93401.1 - 0.03 14.4 0.9 0.044 13.9 0.9 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) TMPIT PF07851.13 CDJ93401.1 - 0.088 12.0 2.9 0.15 11.3 2.9 1.3 1 0 0 1 1 1 0 TMPIT-like protein BLOC1_2 PF10046.9 CDJ93401.1 - 0.82 10.0 7.5 0.51 10.7 2.5 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc24 PF08286.11 CDJ93401.1 - 1.8 8.8 8.0 0.59 10.4 1.6 2.7 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 CLZ PF16526.5 CDJ93401.1 - 2.3 8.6 7.3 0.97 9.8 1.0 2.8 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 CDJ93401.1 - 2.5 8.2 8.2 3.9 7.5 2.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) IPP-2 PF04979.14 CDJ93401.1 - 5.6 7.7 9.3 5.8 7.7 0.4 2.3 1 1 1 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) DEAD PF00270.29 CDJ93402.1 - 4.8e-31 107.9 0.0 1.7e-30 106.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ93402.1 - 2.9e-27 95.2 0.5 8e-27 93.8 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ93402.1 - 0.011 15.7 0.1 0.046 13.7 0.0 2.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit TPR_14 PF13428.6 CDJ93403.1 - 2.2e-11 43.6 3.5 0.8 10.7 0.0 7.3 6 2 2 8 8 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 CDJ93403.1 - 2.6e-08 33.4 0.0 0.0042 16.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ93403.1 - 4.1e-06 27.0 1.3 0.084 13.2 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ93403.1 - 8.8e-06 25.5 1.7 1.9 8.9 0.2 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CDJ93403.1 - 1.3e-05 25.1 11.6 0.51 10.3 0.0 6.0 5 1 1 6 6 6 2 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 CDJ93403.1 - 6.5e-05 22.7 7.0 0.32 11.2 0.2 5.9 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ93403.1 - 0.00066 19.9 1.5 17 6.1 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Suf PF05843.14 CDJ93403.1 - 0.00075 19.6 3.1 8.3 6.3 0.0 4.0 3 1 1 4 4 4 1 Suppressor of forked protein (Suf) TPR_19 PF14559.6 CDJ93403.1 - 0.00087 19.8 0.0 7.6 7.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat NRDE-2 PF08424.10 CDJ93403.1 - 0.0059 15.8 7.6 0.011 14.8 1.0 4.1 2 2 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_16 PF13432.6 CDJ93403.1 - 0.0066 17.1 3.5 14 6.5 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat RPN7 PF10602.9 CDJ93403.1 - 0.076 12.7 0.0 0.94 9.2 0.0 2.5 3 0 0 3 3 3 0 26S proteasome subunit RPN7 DUF3106 PF11304.8 CDJ93403.1 - 0.081 13.4 0.2 23 5.5 0.0 3.0 3 0 0 3 3 2 0 Protein of unknown function (DUF3106) TPR_10 PF13374.6 CDJ93403.1 - 0.1 12.5 3.4 1.3 8.9 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ93403.1 - 0.19 11.8 2.0 4.6 7.5 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ93403.1 - 0.46 11.2 5.0 28 5.6 0.3 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 CDJ93404.1 - 6e-10 38.9 0.0 8.6e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ93404.1 - 1.2e-05 24.7 0.0 1.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Fructosamin_kin PF03881.14 CDJ93404.1 - 0.089 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase CAP PF00188.26 CDJ93406.1 - 6.1e-17 62.6 4.5 9e-17 62.1 4.5 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ93406.1 - 0.0048 17.2 0.5 0.0085 16.4 0.3 1.5 1 1 0 1 1 1 1 Ancylostoma-associated secreted protein related RT_RNaseH_2 PF17919.1 CDJ93407.1 - 1.1e-09 38.2 0.0 1.5e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ93407.1 - 0.00061 20.0 0.0 0.00097 19.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 CDJ93408.1 - 0.00078 20.0 0.0 0.0012 19.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ93408.1 - 0.0021 18.6 0.0 0.0031 18.0 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Mannosyl_trans2 PF04188.13 CDJ93410.1 - 0.099 11.9 12.0 0.13 11.5 12.0 1.1 1 0 0 1 1 1 0 Mannosyltransferase (PIG-V) DUF4728 PF15860.5 CDJ93410.1 - 0.15 12.8 7.0 0.37 11.5 7.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4728) Exo_endo_phos_2 PF14529.6 CDJ93411.1 - 1.7e-05 24.6 0.0 4e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ93411.1 - 2e-05 24.2 0.0 2.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 CDJ93412.1 - 6.4e-08 32.4 0.0 2.4e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Jiraiya PF15038.6 CDJ93413.1 - 5e-14 52.1 14.7 6.8e-14 51.7 14.7 1.1 1 0 0 1 1 1 1 Jiraiya SUR7 PF06687.12 CDJ93413.1 - 0.71 9.5 13.1 0.044 13.4 8.0 1.6 2 0 0 2 2 2 0 SUR7/PalI family DUF3611 PF12263.8 CDJ93413.1 - 1.6 8.6 13.2 1.7 8.5 4.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) Folliculin PF11704.8 CDJ93415.1 - 0.0066 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Mfa1 PF17445.2 CDJ93416.1 - 2.4 8.2 4.2 4.5 7.4 0.7 2.9 2 0 0 2 2 2 0 Mating factor A1 Pkinase PF00069.25 CDJ93417.1 - 2.8e-10 40.0 0.0 8.7e-10 38.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ93417.1 - 9.9e-06 25.0 0.0 5.4e-05 22.6 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase SKA2 PF16740.5 CDJ93417.1 - 0.021 14.6 1.0 0.021 14.6 1.0 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 K-cyclin_vir_C PF09080.10 CDJ93417.1 - 0.6 10.6 5.8 0.075 13.5 1.8 1.6 2 0 0 2 2 2 0 K cyclin, C terminal TFIIA PF03153.13 CDJ93417.1 - 2.8 7.9 9.6 3.3 7.6 9.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C4 PF00105.18 CDJ93419.1 - 3.1e-29 101.2 12.4 5e-29 100.6 12.4 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Anti-TRAP PF15777.5 CDJ93419.1 - 5.9 6.9 10.7 0.37 10.8 0.8 2.4 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein RVT_1 PF00078.27 CDJ93420.1 - 6.6e-35 120.6 0.0 9.9e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Y_phosphatase PF00102.27 CDJ93421.1 - 7.5e-45 153.3 0.1 9.8e-45 152.9 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ93421.1 - 0.034 14.0 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain LRR_4 PF12799.7 CDJ93423.1 - 8.7e-19 67.3 5.6 1.5e-07 31.6 0.6 5.5 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ93423.1 - 7.8e-17 60.8 5.3 8.1e-08 31.9 0.9 3.0 2 1 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 CDJ93423.1 - 1.9e-12 46.1 6.6 0.027 14.5 0.5 6.9 6 0 0 6 6 6 5 Leucine Rich repeat LRR_9 PF14580.6 CDJ93423.1 - 5.4e-10 39.1 2.5 7.9e-07 28.7 0.1 2.9 1 1 2 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 CDJ93423.1 - 0.78 10.5 17.4 47 5.1 0.0 6.7 8 0 0 8 8 8 0 Leucine Rich Repeat Neur_chan_LBD PF02931.23 CDJ93424.1 - 5.1e-34 117.6 0.2 7.4e-34 117.1 0.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF2554 PF10829.8 CDJ93424.1 - 0.15 12.4 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2554) DFP PF04127.15 CDJ93426.1 - 1.7e-05 24.7 0.1 5e-05 23.2 0.0 1.7 1 1 1 2 2 2 1 DNA / pantothenate metabolism flavoprotein Alba PF01918.21 CDJ93427.1 - 4e-11 42.6 0.0 6.8e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Alba TraV PF09676.10 CDJ93427.1 - 0.38 11.7 4.3 2 9.4 2.6 2.1 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) MCM PF00493.23 CDJ93428.1 - 3.5e-100 333.7 0.0 5.4e-100 333.1 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CDJ93428.1 - 9.2e-34 116.0 2.6 9.2e-34 116.0 2.6 1.8 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 CDJ93428.1 - 1.4e-26 92.7 0.3 3.6e-26 91.4 0.3 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CDJ93428.1 - 7.2e-16 58.7 0.1 2.2e-15 57.1 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CDJ93428.1 - 1.3e-06 28.0 0.1 0.00049 19.6 0.0 2.7 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CDJ93428.1 - 8.1e-06 25.9 0.0 4e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CDJ93428.1 - 0.001 18.9 0.0 0.0033 17.3 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CDJ93428.1 - 0.012 15.3 0.0 0.27 10.9 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 CDJ93428.1 - 0.048 14.1 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 CDJ93428.1 - 0.2 12.3 0.9 0.62 10.7 0.1 2.3 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI C-terminal zf-U11-48K PF05253.12 CDJ93428.1 - 1.5 8.8 4.9 2.8 8.0 0.4 2.8 3 0 0 3 3 3 0 U11-48K-like CHHC zinc finger Ribosomal_S7 PF00177.21 CDJ93429.1 - 8.6e-37 126.1 0.5 1.1e-36 125.7 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e ANF_receptor PF01094.28 CDJ93430.1 - 9.9e-08 31.5 0.0 1.1e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region RHH_1 PF01402.21 CDJ93431.1 - 0.1 12.6 0.2 0.26 11.3 0.2 1.7 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family RVT_1 PF00078.27 CDJ93433.1 - 3.4e-15 56.1 0.0 6e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ZapB PF06005.12 CDJ93433.1 - 0.0041 17.5 6.0 0.015 15.7 6.0 2.0 1 0 0 1 1 1 1 Cell division protein ZapB YabA PF06156.13 CDJ93433.1 - 0.0059 17.2 3.8 0.019 15.6 3.8 1.8 1 0 0 1 1 1 1 Initiation control protein YabA DASH_Spc19 PF08287.11 CDJ93433.1 - 0.029 14.2 6.1 0.08 12.8 6.1 1.7 1 0 0 1 1 1 0 Spc19 Ax_dynein_light PF10211.9 CDJ93433.1 - 2 8.3 9.1 0.29 11.1 4.9 1.7 2 0 0 2 2 2 0 Axonemal dynein light chain Spc24 PF08286.11 CDJ93433.1 - 2.9 8.2 6.2 1.6 9.0 2.7 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DivIC PF04977.15 CDJ93433.1 - 6.9 6.5 6.4 18 5.2 6.4 1.7 1 0 0 1 1 1 0 Septum formation initiator ResIII PF04851.15 CDJ93434.1 - 7.3e-09 35.9 0.0 9.2e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ93434.1 - 9.1e-09 35.3 0.0 1.2e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase RSB_motif PF16294.5 CDJ93435.1 - 1.1e-16 60.9 20.2 1.1e-16 60.9 20.2 4.1 2 1 2 4 4 4 1 RNSP1-SAP18 binding (RSB) motif LRR_8 PF13855.6 CDJ93436.1 - 8.3e-41 137.6 38.6 1.1e-08 34.7 10.0 6.8 5 1 0 6 6 6 6 Leucine rich repeat Gelsolin PF00626.22 CDJ93436.1 - 2.6e-40 136.2 0.0 4.5e-13 48.9 0.0 3.7 3 0 0 3 3 3 3 Gelsolin repeat LRR_4 PF12799.7 CDJ93436.1 - 9.3e-31 105.4 40.8 3.9e-05 23.9 0.2 8.6 5 3 2 8 8 8 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDJ93436.1 - 1.6e-07 31.0 20.7 0.015 14.8 0.1 5.1 1 1 4 5 5 5 5 Leucine-rich repeat LRR_1 PF00560.33 CDJ93436.1 - 2e-06 27.5 39.0 7.1 7.6 0.0 12.6 13 0 0 13 13 13 2 Leucine Rich Repeat LRR_5 PF13306.6 CDJ93436.1 - 0.017 15.1 0.2 8.6 6.3 0.0 3.0 1 1 1 3 3 3 0 BspA type Leucine rich repeat region (6 copies) Pentapeptide_4 PF13599.6 CDJ93436.1 - 0.11 12.6 0.0 17 5.6 0.0 3.1 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) DTHCT PF08070.11 CDJ93436.1 - 1.4 9.6 5.7 3.1 8.6 5.7 1.5 1 0 0 1 1 1 0 DTHCT (NUC029) region LRR_6 PF13516.6 CDJ93436.1 - 5.4 7.3 47.6 2.5 8.4 0.0 11.5 12 1 1 13 13 13 0 Leucine Rich repeat Proteasome PF00227.26 CDJ93438.1 - 9e-59 198.2 0.0 1.2e-58 197.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ93438.1 - 1.5e-14 53.3 0.2 2.5e-14 52.6 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PAT1 PF09770.9 CDJ93438.1 - 0.051 11.8 0.0 0.053 11.8 0.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CBFD_NFYB_HMF PF00808.23 CDJ93439.1 - 1.2e-08 35.1 0.0 1.5e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 CDJ93439.1 - 1.2e-07 31.8 0.0 2e-07 31.1 0.0 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CDJ93439.1 - 2.1e-07 31.0 0.0 3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 CDJ93439.1 - 5e-06 26.9 0.0 7.7e-06 26.3 0.0 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CDJ93439.1 - 0.00022 21.3 0.0 0.00029 20.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CDJ93439.1 - 0.00022 21.1 0.0 0.0015 18.5 0.0 1.9 2 0 0 2 2 2 1 Bromodomain associated CENP-S PF15630.6 CDJ93439.1 - 0.00094 19.5 0.2 0.0018 18.6 0.2 1.5 1 1 0 1 1 1 1 CENP-S protein TFIID_20kDa PF03847.13 CDJ93439.1 - 0.0015 19.0 0.0 0.0019 18.6 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TAFII28 PF04719.14 CDJ93439.1 - 0.0017 18.4 0.0 0.0021 18.1 0.0 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region TFIID-18kDa PF02269.16 CDJ93439.1 - 0.089 12.8 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit RNA_pol_A_bac PF01000.26 CDJ93440.1 - 4.7e-39 133.2 0.1 8.2e-39 132.4 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CDJ93440.1 - 2.7e-16 58.7 0.0 3.8e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain WD40 PF00400.32 CDJ93441.1 - 2.3e-42 142.2 10.1 1.1e-08 35.6 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ93441.1 - 2.5e-12 46.9 0.0 0.00025 21.3 0.0 4.4 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 CDJ93441.1 - 4.2e-12 45.4 1.5 4.2e-12 45.4 1.5 2.8 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.11 CDJ93441.1 - 1.2e-08 35.1 0.2 0.0029 17.5 0.2 3.6 2 1 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CDJ93441.1 - 8.7e-06 24.9 0.6 0.035 13.1 0.0 4.6 1 1 3 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Lactonase PF10282.9 CDJ93441.1 - 0.012 14.9 0.1 2.1 7.5 0.0 3.2 2 2 1 3 3 3 0 Lactonase, 7-bladed beta-propeller Cript PF10235.9 CDJ93442.1 - 2.7e-24 85.5 7.7 2.7e-24 85.5 7.7 1.5 1 1 0 1 1 1 1 Microtubule-associated protein CRIPT DUF2039 PF10217.9 CDJ93442.1 - 0.028 14.8 10.0 0.028 14.8 10.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) PUF PF00806.19 CDJ93442.1 - 0.047 13.4 1.5 0.047 13.4 1.5 2.0 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat PLATZ PF04640.14 CDJ93442.1 - 0.19 12.4 9.7 0.1 13.2 4.1 2.6 1 1 2 3 3 3 0 PLATZ transcription factor Gin PF10764.9 CDJ93442.1 - 0.21 11.6 12.7 3.4 7.7 0.1 3.1 2 1 1 3 3 3 0 Inhibitor of sigma-G Gin DEAD PF00270.29 CDJ93443.1 - 5.3e-35 120.8 0.0 2.2e-34 118.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ93443.1 - 5.3e-28 97.6 0.0 1.7e-27 96.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ93443.1 - 1.3e-05 25.3 1.0 2.7e-05 24.2 0.0 2.1 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 CDJ93443.1 - 0.0044 16.4 0.0 0.012 15.0 0.0 1.7 2 0 0 2 2 2 1 SecA DEAD-like domain F-box_4 PF15966.5 CDJ93445.1 - 0.034 14.0 0.3 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 F-box F-box-like PF12937.7 CDJ93445.1 - 0.075 12.9 0.4 0.22 11.5 0.4 1.8 1 0 0 1 1 1 0 F-box-like Ion_trans_2 PF07885.16 CDJ93446.1 - 7.4e-29 99.5 19.7 4.2e-16 58.7 3.5 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 CDJ93446.1 - 0.00011 21.6 14.5 0.003 16.8 1.5 2.3 2 0 0 2 2 2 2 Ion transport protein IRK PF01007.20 CDJ93446.1 - 0.0021 17.9 1.8 0.27 11.1 0.4 2.5 2 0 0 2 2 2 2 Inward rectifier potassium channel transmembrane domain DUF2970 PF11174.8 CDJ93446.1 - 0.33 10.8 3.4 0.66 9.9 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) Lig_chan PF00060.26 CDJ93446.1 - 3.2 7.6 5.5 10 5.9 0.5 2.8 3 0 0 3 3 3 0 Ligand-gated ion channel ARID PF01388.21 CDJ93448.1 - 8.3e-17 61.6 0.1 1.7e-16 60.6 0.1 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Chromo PF00385.24 CDJ93449.1 - 7.2e-08 32.2 0.3 1.4e-07 31.3 0.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ank_2 PF12796.7 CDJ93449.1 - 6.6e-06 26.6 0.0 2.6e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDJ93449.1 - 0.00015 21.9 0.3 0.09 13.4 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 CDJ93449.1 - 0.00027 21.1 0.5 0.021 15.1 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CDJ93449.1 - 0.0051 17.2 0.1 0.29 11.7 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeat ETC_C1_NDUFA4 PF04800.12 CDJ93450.1 - 2e-35 120.9 1.4 2.5e-35 120.6 1.4 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region SSXT PF05030.12 CDJ93451.1 - 2.3e-20 72.0 0.3 3.8e-20 71.3 0.3 1.3 1 0 0 1 1 1 1 SSXT protein (N-terminal region) PP2C PF00481.21 CDJ93452.1 - 4.8e-36 124.7 0.0 6.8e-34 117.7 0.0 2.2 1 1 0 2 2 2 2 Protein phosphatase 2C Collagen PF01391.18 CDJ93453.1 - 4.1e-21 74.5 117.8 3.2e-09 36.4 41.0 4.0 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ93453.1 - 1.3e-20 73.2 0.3 1.6e-20 72.9 0.3 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain CcmD PF04995.14 CDJ93454.1 - 0.13 12.4 0.3 0.26 11.4 0.3 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) LapA_dom PF06305.11 CDJ93454.1 - 0.45 10.4 1.6 0.91 9.4 1.6 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain NOA36 PF06524.12 CDJ93454.1 - 1.8 7.8 15.3 3.6 6.8 3.1 2.3 2 0 0 2 2 2 0 NOA36 protein PA26 PF04636.13 CDJ93454.1 - 1.8 7.4 12.1 2.6 6.9 12.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) LAP1C PF05609.12 CDJ93454.1 - 3.7 6.5 15.1 5.7 5.9 15.1 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SID-1_RNA_chan PF13965.6 CDJ93454.1 - 3.8 5.8 6.0 66 1.7 6.9 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF4611 PF15387.6 CDJ93454.1 - 6.9 7.0 19.8 0.38 11.0 4.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) ResIII PF04851.15 CDJ93456.1 - 0.086 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TPR_1 PF00515.28 CDJ93457.1 - 2.6e-10 39.7 0.1 0.00013 21.6 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ93457.1 - 9.5e-10 37.8 0.1 0.00011 22.0 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ93457.1 - 5.1e-07 29.3 0.2 8.9e-07 28.5 0.2 1.4 1 0 0 1 1 1 1 TPR repeat TPR_19 PF14559.6 CDJ93457.1 - 1.1e-06 29.0 0.0 2.3e-06 28.0 0.1 1.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ93457.1 - 5.8e-06 26.9 0.2 8.8e-06 26.3 0.2 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ93457.1 - 6.6e-06 26.5 0.2 0.0051 17.5 0.3 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ93457.1 - 4.7e-05 23.3 0.0 0.011 15.9 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ93457.1 - 0.0006 20.0 0.6 0.002 18.3 0.1 2.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ93457.1 - 0.00064 20.0 0.1 0.0071 16.6 0.1 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_20 PF14561.6 CDJ93457.1 - 0.001 19.4 0.1 0.17 12.3 0.1 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ93457.1 - 0.0015 18.6 0.1 0.0024 18.0 0.0 1.4 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ93457.1 - 0.022 15.4 0.0 1.9 9.3 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Bep_C_terminal PF17841.1 CDJ93457.1 - 0.039 14.2 0.0 0.057 13.7 0.0 1.2 1 0 0 1 1 1 0 BID domain of Bartonella effector protein (Bep) TPR_7 PF13176.6 CDJ93457.1 - 0.057 13.5 0.0 1 9.6 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF915 PF06028.11 CDJ93457.1 - 0.092 12.1 0.0 0.18 11.1 0.0 1.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) BTAD PF03704.17 CDJ93457.1 - 0.098 13.1 0.0 0.12 12.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial transcriptional activator domain Pkinase PF00069.25 CDJ93459.1 - 6.9e-07 28.9 0.0 8.2e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain ABC1 PF03109.16 CDJ93459.1 - 0.061 13.5 0.0 0.071 13.3 0.0 1.2 1 0 0 1 1 1 0 ABC1 family Pkinase_Tyr PF07714.17 CDJ93459.1 - 0.16 11.2 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 CDJ93460.1 - 1.2e-58 198.6 0.0 1.9e-58 197.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ93460.1 - 3.1e-47 161.0 0.0 5.1e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ93460.1 - 2.7e-10 39.6 0.0 4e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDJ93460.1 - 0.042 13.2 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-CCHC_5 PF14787.6 CDJ93461.1 - 0.0085 15.8 2.7 0.023 14.4 2.7 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger gag-asp_proteas PF13975.6 CDJ93461.1 - 0.02 15.5 0.1 0.048 14.2 0.1 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC_3 PF13917.6 CDJ93461.1 - 0.028 14.4 1.6 0.076 13.0 1.6 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 CDJ93461.1 - 0.23 11.6 2.4 0.74 10.0 2.4 1.9 1 0 0 1 1 1 0 Zinc knuckle Exo70 PF03081.15 CDJ93462.1 - 5.1e-47 160.7 1.2 5.1e-47 160.7 1.2 1.7 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Sec34 PF04136.15 CDJ93462.1 - 6e-06 26.2 1.9 2.5e-05 24.2 1.9 2.1 1 1 0 1 1 1 1 Sec34-like family Exonuc_VII_L PF02601.15 CDJ93462.1 - 0.41 10.2 6.1 0.19 11.3 2.8 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit NUDIX PF00293.28 CDJ93463.1 - 4e-12 46.3 0.1 2.2e-11 43.9 0.1 2.0 1 1 0 1 1 1 1 NUDIX domain KorB PF08535.10 CDJ93463.1 - 0.085 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 KorB domain zf-HC5HC2H_2 PF13832.6 CDJ93464.1 - 5.9e-30 103.7 18.0 7.2e-29 100.2 7.3 2.4 2 1 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CDJ93464.1 - 1.7e-22 79.5 20.7 8.8e-22 77.2 5.9 2.9 2 1 1 3 3 3 2 PHD-like zinc-binding domain PHD_2 PF13831.6 CDJ93464.1 - 3.1e-13 49.0 3.3 3.1e-13 49.0 3.3 3.4 3 0 0 3 3 3 1 PHD-finger PHD PF00628.29 CDJ93464.1 - 1.2e-08 34.7 9.2 1.2e-08 34.7 9.2 3.5 4 1 0 4 4 4 1 PHD-finger Anti-TRAP PF15777.5 CDJ93464.1 - 0.3 11.1 7.0 0.37 10.8 3.8 2.6 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein FANCL_C PF11793.8 CDJ93464.1 - 1.1 9.5 18.8 2.4 8.4 6.9 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain FYVE_2 PF02318.16 CDJ93464.1 - 1.3 9.2 16.5 0.2 11.9 1.7 2.7 3 0 0 3 3 3 0 FYVE-type zinc finger zf-PHD-like PF15446.6 CDJ93464.1 - 2.9 7.5 17.9 0.21 11.2 2.6 2.8 2 2 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Homeodomain PF00046.29 CDJ93465.1 - 9.1e-21 73.5 3.9 1.4e-20 72.8 3.9 1.3 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 CDJ93465.1 - 0.0022 17.4 0.3 0.0055 16.2 0.3 1.7 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 CDJ93465.1 - 0.003 17.4 0.1 0.0066 16.3 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain DNApol_Exo PF18136.1 CDJ93465.1 - 0.07 12.2 0.5 0.099 11.8 0.5 1.2 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain YdaS_antitoxin PF15943.5 CDJ93465.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF4890 PF16231.5 CDJ93466.1 - 0.022 15.3 3.3 0.022 15.3 3.3 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4890) CCER1 PF15482.6 CDJ93466.1 - 0.17 11.7 0.1 0.3 11.0 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 Tombus_movement PF05318.12 CDJ93466.1 - 0.21 12.4 2.1 0.64 10.9 2.1 1.8 1 0 0 1 1 1 0 Tombusvirus movement protein HAD_2 PF13419.6 CDJ93467.1 - 1.1e-19 71.2 0.0 1.9e-19 70.4 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDJ93467.1 - 2.5e-18 67.2 0.0 1.2e-17 64.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CDJ93467.1 - 2.7e-10 40.2 0.0 5.7e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 CDJ93467.1 - 1.5e-06 28.8 0.0 2.3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDJ93467.1 - 0.004 16.9 0.0 0.12 12.1 0.0 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CDJ93467.1 - 0.033 14.3 0.0 5 7.3 0.0 2.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase BSP_II PF05432.11 CDJ93468.1 - 0.014 15.1 23.1 0.021 14.5 23.1 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF4746 PF15928.5 CDJ93468.1 - 0.049 13.0 14.7 0.091 12.2 14.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NPR3 PF03666.13 CDJ93468.1 - 0.62 8.8 6.8 1 8.1 6.8 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TFIIF_alpha PF05793.12 CDJ93468.1 - 0.76 8.3 29.1 1.1 7.8 29.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Zip PF02535.22 CDJ93468.1 - 1.3 8.2 3.9 2 7.6 3.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PPP4R2 PF09184.11 CDJ93468.1 - 2.1 7.9 19.9 3 7.4 19.9 1.2 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 CDJ93468.1 - 5.2 6.4 28.5 7.2 5.9 28.5 1.1 1 0 0 1 1 1 0 SDA1 EXOSC1 PF10447.9 CDJ93470.1 - 2.2e-08 34.7 0.8 0.00062 20.3 0.1 2.4 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 CDJ93470.1 - 2.6e-06 27.1 0.7 6.4e-06 25.9 0.2 1.9 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region INTS2 PF14750.6 CDJ93471.1 - 6.4e-109 365.1 16.7 1.4e-108 363.9 16.7 1.5 1 1 0 1 1 1 1 Integrator complex subunit 2 Importin_rep_3 PF18806.1 CDJ93471.1 - 0.028 14.4 0.0 0.2 11.7 0.0 2.6 1 0 0 1 1 1 0 Importin 13 repeat CSF-1 PF05337.11 CDJ93471.1 - 0.14 12.3 0.2 4.6 7.3 0.0 2.4 2 0 0 2 2 2 0 Macrophage colony stimulating factor-1 (CSF-1) Peptidase_C54 PF03416.19 CDJ93472.1 - 1.2e-93 313.5 0.0 1.9e-93 312.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C54 Pribosyltran PF00156.27 CDJ93472.1 - 1.2e-16 60.6 0.1 2.3e-16 59.7 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Ribosomal_S6 PF01250.17 CDJ93472.1 - 9.9e-07 29.0 0.0 2.2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S6 DUF2344 PF10105.9 CDJ93472.1 - 0.15 11.9 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) WD40 PF00400.32 CDJ93473.1 - 8.2e-21 73.9 4.2 0.00074 20.3 0.7 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ93473.1 - 6.7e-19 68.0 0.2 0.0025 18.0 0.0 6.4 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 CDJ93473.1 - 5.9e-07 28.3 0.0 2.6e-05 22.9 0.0 2.2 1 1 1 2 2 2 1 Cytochrome D1 heme domain eIF2A PF08662.11 CDJ93473.1 - 1.3e-05 25.2 0.0 0.0018 18.2 0.0 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CDJ93473.1 - 0.00097 18.5 0.0 7.8 5.7 0.0 4.2 2 1 2 4 4 4 1 WD40-like domain DPPIV_N PF00930.21 CDJ93473.1 - 0.028 13.2 0.0 0.28 9.9 0.0 2.4 3 0 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Lactonase PF10282.9 CDJ93473.1 - 0.051 12.8 0.0 0.53 9.5 0.0 2.2 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller Frtz PF11768.8 CDJ93473.1 - 0.052 11.9 0.0 14 3.8 0.0 3.0 1 1 3 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz Gmad1 PF10647.9 CDJ93473.1 - 0.077 12.7 2.3 5.7 6.6 0.1 3.1 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain Ge1_WD40 PF16529.5 CDJ93473.1 - 0.15 10.9 0.4 32 3.3 0.0 3.7 2 2 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CDO_I PF05995.12 CDJ93474.1 - 7e-40 136.1 0.0 8.3e-40 135.8 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 CDJ93474.1 - 0.02 14.3 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 PCO_ADO TPR_8 PF13181.6 CDJ93475.1 - 2.8e-06 27.1 2.7 0.00032 20.7 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ93475.1 - 0.00045 20.1 2.7 0.59 10.4 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ93475.1 - 0.002 18.3 0.1 1.4 9.2 0.0 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CDJ93475.1 - 0.014 16.0 0.0 0.35 11.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ93475.1 - 0.15 11.9 3.5 1.2 9.1 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Jagunal PF07086.12 CDJ93476.1 - 1.4e-71 240.5 4.3 1.6e-71 240.3 4.3 1.0 1 0 0 1 1 1 1 Jagunal, ER re-organisation during oogenesis Mcm10 PF09332.11 CDJ93477.1 - 1.3e-50 172.9 23.3 1.3e-50 172.9 23.3 2.6 2 1 0 2 2 2 1 Mcm10 replication factor Proteasome PF00227.26 CDJ93477.1 - 1.9e-40 138.4 0.7 3.2e-40 137.6 0.7 1.4 1 0 0 1 1 1 1 Proteasome subunit zf-primase PF09329.11 CDJ93477.1 - 1.6e-14 53.4 0.5 5.4e-14 51.7 0.5 2.0 1 0 0 1 1 1 1 Primase zinc finger Zn-ribbon_8 PF09723.10 CDJ93477.1 - 0.062 13.4 4.9 0.4 10.8 0.7 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Neuropep_like PF15161.6 CDJ93477.1 - 0.12 12.1 0.1 0.31 10.7 0.1 1.8 1 0 0 1 1 1 0 Neuropeptide-like Cytochrome_C7 PF14522.6 CDJ93477.1 - 0.14 12.2 9.6 0.45 10.5 9.6 1.9 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c OrfB_Zn_ribbon PF07282.11 CDJ93477.1 - 4.8 7.2 6.1 28 4.7 1.2 2.7 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Calpain_III PF01067.22 CDJ93478.1 - 3.6e-14 53.2 0.0 4.5e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Calpain large subunit, domain III RVT_1 PF00078.27 CDJ93479.1 - 2e-23 83.1 0.0 2.2e-23 83.0 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PP1_bind PF15276.6 CDJ93479.1 - 0.036 14.4 0.0 0.08 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein phosphatase 1 binding RVT_1 PF00078.27 CDJ93480.1 - 1.4e-09 37.8 0.0 2.1e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rgp1 PF08737.10 CDJ93481.1 - 0.6 9.2 5.6 0.69 9.0 5.6 1.0 1 0 0 1 1 1 0 Rgp1 MAP17 PF15807.5 CDJ93481.1 - 3.1 8.1 11.9 3.6 7.8 11.9 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 FAM176 PF14851.6 CDJ93481.1 - 5.1 6.8 11.7 7 6.3 11.7 1.2 1 0 0 1 1 1 0 FAM176 family Presenilin PF01080.17 CDJ93481.1 - 5.6 5.6 7.1 6.6 5.4 7.1 1.0 1 0 0 1 1 1 0 Presenilin Sec62 PF03839.16 CDJ93481.1 - 7.1 6.1 13.3 8.1 5.9 13.3 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 Forkhead PF00250.18 CDJ93482.1 - 8.7e-39 131.7 0.1 1.3e-38 131.1 0.1 1.3 1 0 0 1 1 1 1 Forkhead domain 7tm_1 PF00001.21 CDJ93483.1 - 9.5e-20 71.0 22.0 1.2e-19 70.7 22.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDJ93483.1 - 1.5e-15 57.4 24.2 2e-15 56.9 24.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw CBP4 PF07960.11 CDJ93484.1 - 0.94 9.3 3.2 0.34 10.8 0.4 1.6 2 0 0 2 2 2 0 CBP4 FANCF PF11107.8 CDJ93485.1 - 0.045 13.0 0.3 0.24 10.6 0.0 1.8 1 1 1 2 2 2 0 Fanconi anemia group F protein (FANCF) 4HB_MCP_1 PF12729.7 CDJ93487.1 - 0.0065 16.0 0.1 0.077 12.5 0.0 2.0 2 0 0 2 2 2 1 Four helix bundle sensory module for signal transduction DUF4358 PF14270.6 CDJ93487.1 - 0.17 12.2 0.4 0.65 10.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) PSK_trans_fac PF07704.11 CDJ93487.1 - 0.19 12.5 1.8 0.29 11.9 0.3 2.1 2 1 0 2 2 2 0 Rv0623-like transcription factor HSP20 PF00011.21 CDJ93488.1 - 8.8e-22 77.2 0.1 1.1e-21 76.8 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ93488.1 - 0.045 13.3 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 HSP20-like domain found in ArsA PAN_1 PF00024.26 CDJ93489.1 - 1.9e-06 27.7 10.7 0.00012 22.0 3.8 2.4 2 1 0 2 2 2 2 PAN domain PAN_4 PF14295.6 CDJ93489.1 - 3.1e-05 23.8 4.0 3.1e-05 23.8 4.0 2.4 2 1 0 2 2 2 1 PAN domain Ig_3 PF13927.6 CDJ93490.1 - 2.8e-06 27.8 0.3 6.5e-06 26.7 0.1 1.7 2 0 0 2 2 2 1 Immunoglobulin domain Ig_5 PF16681.5 CDJ93490.1 - 3.7e-05 24.1 0.0 7.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain EGF PF00008.27 CDJ93490.1 - 0.0021 18.3 3.1 0.0046 17.2 3.1 1.6 1 0 0 1 1 1 1 EGF-like domain Ig_2 PF13895.6 CDJ93490.1 - 0.0027 18.0 0.1 0.0084 16.4 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 CDJ93490.1 - 0.013 15.7 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain Ac76 PF05814.11 CDJ93490.1 - 0.096 12.7 0.5 3.6 7.7 0.1 2.2 2 0 0 2 2 2 0 Orf76 (Ac76) Ank_4 PF13637.6 CDJ93490.1 - 0.097 13.3 0.1 0.2 12.3 0.1 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) EGF_2 PF07974.13 CDJ93490.1 - 0.52 10.7 8.9 1 9.8 8.9 1.6 1 0 0 1 1 1 0 EGF-like domain Tmpp129 PF10272.9 CDJ93492.1 - 7.5e-72 242.6 4.1 1e-71 242.1 4.1 1.1 1 0 0 1 1 1 1 Putative transmembrane protein precursor Myosin_head PF00063.21 CDJ93493.1 - 8.3e-119 397.7 8.3 9.9e-119 397.5 7.8 1.3 1 1 1 2 2 2 1 Myosin head (motor domain) IQ PF00612.27 CDJ93493.1 - 4.1e-05 23.0 9.9 0.027 14.2 0.8 2.6 2 0 0 2 2 2 2 IQ calmodulin-binding motif DUF4479 PF14794.6 CDJ93493.1 - 1.9 8.4 4.3 0.76 9.7 0.4 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4479) DEAD PF00270.29 CDJ93494.1 - 1.3e-46 158.6 0.8 1.7e-46 158.2 0.8 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ93494.1 - 1.8e-08 34.6 0.0 2.4e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CDJ93494.1 - 4.1e-05 23.4 0.1 5.7e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ93494.1 - 0.00023 21.5 0.6 0.00038 20.8 0.6 1.4 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 CDJ93494.1 - 0.00081 19.3 0.1 0.0015 18.4 0.1 1.4 1 1 0 1 1 1 1 Helicase CMS1 PF14617.6 CDJ93494.1 - 0.0027 17.1 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 CDJ93494.1 - 0.011 16.0 0.6 0.071 13.4 0.3 2.3 2 1 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.14 CDJ93494.1 - 0.023 14.7 0.4 0.11 12.5 0.4 2.0 1 1 0 1 1 1 0 Flavivirus DEAD domain UvrD-helicase PF00580.21 CDJ93494.1 - 0.11 12.0 0.2 0.13 11.7 0.2 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain MCM_lid PF17855.1 CDJ93496.1 - 1.9e-27 95.5 0.5 3.7e-27 94.6 0.5 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase_C PF13335.6 CDJ93496.1 - 0.023 15.3 0.1 0.053 14.2 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal BTAD PF03704.17 CDJ93496.1 - 0.067 13.6 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial transcriptional activator domain Mito_fiss_reg PF05308.11 CDJ93497.1 - 6.8 6.7 8.7 5.1 7.1 7.4 1.4 1 1 1 2 2 2 0 Mitochondrial fission regulator F-box-like PF12937.7 CDJ93498.1 - 8.8e-05 22.3 0.1 0.00024 20.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDJ93498.1 - 0.00018 21.3 0.4 0.00038 20.2 0.4 1.6 1 0 0 1 1 1 1 F-box domain Ribosomal_L30 PF00327.20 CDJ93498.1 - 0.18 11.7 1.3 3.7 7.5 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein L30p/L7e PNTB PF02233.16 CDJ93500.1 - 1.9e-180 600.7 16.3 1.9e-180 600.7 16.3 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 CDJ93500.1 - 5.6e-76 254.6 0.2 1.2e-75 253.5 0.2 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 CDJ93500.1 - 3.1e-44 150.6 0.2 6.4e-44 149.6 0.2 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 CDJ93500.1 - 1e-30 106.0 2.1 1e-30 106.0 2.1 3.9 4 0 0 4 4 4 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 CDJ93500.1 - 0.017 14.5 0.2 7.4 5.9 0.2 2.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aminotran_5 PF00266.19 CDJ93501.1 - 2.3e-07 30.1 0.0 2.5e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Vitellogenin_N PF01347.22 CDJ93502.1 - 2.6e-112 376.3 6.6 2.6e-112 376.3 6.6 1.6 2 0 0 2 2 2 1 Lipoprotein amino terminal region DUF1943 PF09172.11 CDJ93502.1 - 1.2e-56 192.2 1.6 1.2e-56 192.2 1.6 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1943) VWD PF00094.25 CDJ93502.1 - 8.2e-21 74.9 2.6 1.2e-20 74.4 1.2 2.1 2 0 0 2 2 2 1 von Willebrand factor type D domain Aminotran_4 PF01063.19 CDJ93503.1 - 3.8e-31 108.7 0.0 4.9e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Ion_trans PF00520.31 CDJ93504.1 - 2.7e-36 125.0 12.6 4.8e-36 124.2 12.6 1.5 1 1 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 CDJ93504.1 - 1.4e-19 70.2 0.1 2.9e-19 69.2 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 CDJ93504.1 - 9.2e-13 48.0 7.3 9.2e-13 48.0 7.3 2.3 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 CDJ93504.1 - 0.028 14.5 0.1 0.065 13.3 0.1 1.6 1 0 0 1 1 1 0 BTB/POZ domain FERM_C PF09380.10 CDJ93505.1 - 4.8e-12 46.1 0.0 7.1e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 FERM C-terminal PH-like domain Helicase_C PF00271.31 CDJ93508.1 - 3.5e-21 75.6 0.0 1.9e-17 63.6 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ93508.1 - 9.3e-18 64.6 0.0 1.8e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RQC PF09382.10 CDJ93508.1 - 4.1e-14 52.3 0.0 1.2e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 CDJ93508.1 - 5.3e-12 45.5 0.0 1.1e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 HRDC domain RecQ_Zn_bind PF16124.5 CDJ93508.1 - 6.5e-07 30.0 1.9 8.8e-07 29.6 0.7 1.9 2 0 0 2 2 2 1 RecQ zinc-binding HTH_40 PF14493.6 CDJ93508.1 - 8.3e-06 26.2 0.0 2.2e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain ResIII PF04851.15 CDJ93508.1 - 0.013 15.5 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit LSDAT_prok PF18171.1 CDJ93508.1 - 0.16 11.2 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Carboxyl_trans PF01039.22 CDJ93509.1 - 1.7e-155 518.4 0.1 2.4e-155 517.9 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Ribonuclease_3 PF00636.26 CDJ93509.1 - 0.0051 17.4 0.1 0.03 14.9 0.1 2.2 1 1 0 1 1 1 1 Ribonuclease III domain MdcE PF06833.11 CDJ93509.1 - 0.0078 15.7 0.4 0.16 11.4 0.0 2.3 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) ApoLp-III PF07464.11 CDJ93509.1 - 0.048 13.7 0.2 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Cyclin_N PF00134.23 CDJ93510.1 - 7.4e-47 158.3 0.5 7.4e-47 158.3 0.5 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CDJ93510.1 - 3.8e-20 72.1 0.0 6e-19 68.3 0.0 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N2 PF16500.5 CDJ93510.1 - 0.014 16.2 0.9 0.027 15.2 0.9 1.5 1 0 0 1 1 1 0 N-terminal region of cyclin_N Thiolase_N PF00108.23 CDJ93511.1 - 5.4e-88 294.7 0.3 8.7e-88 294.0 0.3 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CDJ93511.1 - 1.5e-52 176.5 1.2 7.2e-52 174.2 0.3 2.5 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CDJ93511.1 - 2.3e-05 24.1 0.1 0.00013 21.6 0.1 2.3 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 CDJ93511.1 - 0.052 13.7 0.1 0.66 10.2 0.0 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 CDJ93511.1 - 0.08 12.8 1.2 3.4 7.6 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CS PF04969.16 CDJ93512.1 - 1.6e-17 64.2 1.7 2e-17 64.0 0.7 1.7 2 0 0 2 2 2 1 CS domain LON_substr_bdg PF02190.16 CDJ93513.1 - 1.2e-13 51.4 0.5 1.6e-13 51.0 0.5 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-Di19 PF05605.12 CDJ93514.1 - 0.002 18.4 5.5 0.002 18.4 5.5 4.9 4 1 1 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 CDJ93514.1 - 0.045 14.6 35.5 0.066 14.1 2.0 6.4 6 0 0 6 6 6 0 C2H2-type zinc finger zf-FCS PF06467.14 CDJ93514.1 - 0.061 13.3 10.8 0.089 12.7 0.1 4.0 5 0 0 5 5 5 0 MYM-type Zinc finger with FCS sequence motif HypA PF01155.19 CDJ93514.1 - 0.14 12.2 10.4 2 8.4 2.1 2.7 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DnaJ_CXXCXGXG PF00684.19 CDJ93514.1 - 0.21 12.0 0.1 0.21 12.0 0.1 2.9 3 1 0 3 3 3 0 DnaJ central domain zf-C2H2_2 PF12756.7 CDJ93514.1 - 1 9.8 22.9 0.059 13.7 3.0 3.5 1 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) DZR PF12773.7 CDJ93514.1 - 5 7.2 10.2 1.8e+02 2.2 3.3 2.9 1 1 1 2 2 2 0 Double zinc ribbon zf_ZIC PF18366.1 CDJ93514.1 - 7.3 6.8 9.8 0.12 12.5 0.8 2.5 3 0 0 3 3 3 0 Zic proteins zinc finger domain PTPLA PF04387.14 CDJ93515.1 - 1.4e-29 102.9 5.2 2.7e-29 102.0 5.2 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA EGF_3 PF12947.7 CDJ93517.1 - 6.8e-61 202.2 290.6 7.9e-10 38.8 6.9 19.5 19 0 0 19 19 19 14 EGF domain EGF_CA PF07645.15 CDJ93517.1 - 1e-36 124.9 113.5 9.7e-10 38.5 11.8 18.8 19 1 1 20 20 20 9 Calcium-binding EGF domain cEGF PF12662.7 CDJ93517.1 - 3.5e-15 55.6 196.1 0.00021 21.1 5.6 20.5 20 0 0 20 20 20 14 Complement Clr-like EGF-like EGF PF00008.27 CDJ93517.1 - 4.3e-14 52.5 239.9 4.6e-06 26.8 5.4 18.9 18 0 0 18 18 18 10 EGF-like domain fn3 PF00041.21 CDJ93518.1 - 2.2e-37 127.3 8.9 9.7e-12 45.1 0.3 5.7 5 1 1 6 6 6 3 Fibronectin type III domain Ig_3 PF13927.6 CDJ93518.1 - 2.8e-20 72.7 4.6 1.4e-07 32.0 0.1 4.1 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 CDJ93518.1 - 3.3e-18 65.6 0.2 2.2e-11 43.8 0.1 3.5 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 CDJ93518.1 - 1.7e-16 60.1 1.5 4.8e-07 29.8 0.0 5.0 4 2 0 4 4 4 3 Immunoglobulin I-set domain Pur_ac_phosph_N PF16656.5 CDJ93518.1 - 1.1e-10 41.9 0.0 0.0082 16.7 0.0 5.6 5 0 0 5 5 5 2 Purple acid Phosphatase, N-terminal domain Ig_2 PF13895.6 CDJ93518.1 - 1.8e-09 37.8 1.1 0.0014 18.9 0.1 3.9 3 0 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.12 CDJ93518.1 - 5.2e-06 26.4 0.9 0.074 13.1 0.0 3.6 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 CDJ93518.1 - 0.014 15.4 0.0 7.8 6.6 0.0 2.8 2 0 0 2 2 2 0 C17orf99 Ig domain cEGF PF12662.7 CDJ93518.1 - 0.028 14.4 1.7 0.07 13.1 1.7 1.7 1 0 0 1 1 1 0 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CDJ93518.1 - 0.086 13.1 7.4 0.21 11.9 7.4 1.7 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site DUF3659 PF12396.8 CDJ93518.1 - 0.39 10.7 7.9 4.1 7.4 0.4 5.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3659) PAX PF00292.18 CDJ93519.1 - 3.6e-09 36.6 0.1 6.3e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 CDJ93519.1 - 5.3e-07 29.3 0.1 9.5e-07 28.4 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 CDJ93519.1 - 1.3e-06 28.1 0.2 2.7e-06 27.0 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 CDJ93519.1 - 1e-05 25.5 0.1 1.8e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 CDJ93519.1 - 0.00023 21.2 0.1 0.00041 20.4 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 CDJ93519.1 - 0.0084 16.1 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix Terminase_5 PF06056.12 CDJ93519.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) CENP-B_N PF04218.13 CDJ93519.1 - 0.024 14.2 0.5 0.045 13.4 0.1 1.6 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_Crp_2 PF13545.6 CDJ93519.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_Tnp_1 PF01527.20 CDJ93519.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Transposase CD20 PF04103.15 CDJ93521.1 - 1e-23 84.2 9.2 1.2e-23 83.9 9.2 1.1 1 0 0 1 1 1 1 CD20-like family CBP PF12192.8 CDJ93521.1 - 0.89 9.8 3.4 3.9 7.7 0.3 2.2 2 0 0 2 2 2 0 Fungal calcium binding protein CRPA PF05745.11 CDJ93521.1 - 3.3 7.7 8.2 0.39 10.7 1.4 2.1 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Cullin_binding PF03556.15 CDJ93522.1 - 1.1e-34 119.5 0.2 1.1e-34 119.5 0.2 2.0 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.6 CDJ93522.1 - 8.2e-10 38.4 2.1 9.5e-10 38.1 0.0 2.2 3 0 0 3 3 3 1 UBA-like domain PHA_synth_III_E PF09712.10 CDJ93522.1 - 0.012 14.8 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) TAP_C PF03943.13 CDJ93522.1 - 0.024 14.3 1.9 0.037 13.7 0.9 1.9 2 0 0 2 2 2 0 TAP C-terminal domain Med21 PF11221.8 CDJ93523.1 - 1.1e-14 55.0 1.8 2e-12 47.6 1.8 2.0 1 1 0 1 1 1 1 Subunit 21 of Mediator complex DIM1 PF02966.16 CDJ93524.1 - 4.6e-66 220.6 0.0 5.1e-66 220.5 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 CDJ93524.1 - 3.4e-05 23.8 0.0 4.5e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CDJ93524.1 - 0.012 15.9 0.2 0.018 15.4 0.2 1.3 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_7 PF13899.6 CDJ93524.1 - 0.017 15.3 0.0 0.033 14.4 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin-like LRR_6 PF13516.6 CDJ93525.1 - 0.0029 17.5 0.4 2.1 8.6 0.0 3.6 4 0 0 4 4 4 1 Leucine Rich repeat RanGAP1_C PF07834.11 CDJ93525.1 - 0.005 16.5 0.1 0.008 15.8 0.1 1.3 1 0 0 1 1 1 1 RanGAP1 C-terminal domain TFIIF_alpha PF05793.12 CDJ93525.1 - 0.006 15.2 0.1 0.0097 14.5 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4326 PF14216.6 CDJ93525.1 - 0.095 13.4 0.1 0.24 12.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4326) Phage-tail_3 PF13550.6 CDJ93526.1 - 0.029 14.2 0.8 0.046 13.6 0.8 1.3 1 0 0 1 1 1 0 Putative phage tail protein Colicin_E5 PF12106.8 CDJ93526.1 - 0.11 12.8 0.7 0.21 11.9 0.6 1.5 1 1 0 1 1 1 0 Colicin E5 ribonuclease domain ATF7IP_BD PF16788.5 CDJ93526.1 - 0.24 11.5 2.4 0.33 11.0 2.4 1.2 1 0 0 1 1 1 0 ATF-interacting protein binding domain FlaC_arch PF05377.11 CDJ93527.1 - 0.0018 18.6 2.0 0.0018 18.6 2.0 11.5 11 3 2 13 13 13 1 Flagella accessory protein C (FlaC) OprB PF04966.12 CDJ93527.1 - 0.26 10.6 0.4 0.5 9.7 0.4 1.4 1 0 0 1 1 1 0 Carbohydrate-selective porin, OprB family GlcNAc-1_reg PF18440.1 CDJ93527.1 - 0.48 10.7 11.2 0.091 13.0 0.7 4.4 4 0 0 4 4 4 0 Putative GlcNAc-1 phosphotransferase regulatory domain Pkinase PF00069.25 CDJ93529.1 - 3e-23 82.6 0.0 4.1e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ93529.1 - 3.1e-20 72.6 0.0 5.7e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.23 CDJ93529.1 - 6.4e-09 36.8 12.1 1.2e-08 35.9 12.1 1.4 1 0 0 1 1 1 1 Activin types I and II receptor domain TGF_beta_GS PF08515.12 CDJ93529.1 - 9.4e-06 25.0 0.0 1.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif APH PF01636.23 CDJ93529.1 - 0.052 13.5 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 CDJ93529.1 - 0.078 12.6 0.0 0.17 11.5 0.0 1.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF3290 PF11694.8 CDJ93529.1 - 0.13 12.3 0.0 0.41 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) DUF3037 PF11236.8 CDJ93530.1 - 0.36 11.3 2.7 30 5.1 1.3 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) HSBP1 PF06825.12 CDJ93530.1 - 2.2 8.2 5.4 4.5 7.2 1.5 2.8 2 1 0 2 2 2 0 Heat shock factor binding protein 1 Kunitz_BPTI PF00014.23 CDJ93533.1 - 6.6e-25 87.1 10.9 4.8e-12 45.9 0.9 3.6 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain EB PF01683.18 CDJ93533.1 - 1.1e-13 51.2 15.5 7.1e-10 39.0 9.0 6.1 4 2 1 5 5 5 2 EB module SCVP PF17619.2 CDJ93535.1 - 2.4e-09 37.9 0.1 3.5e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Secreted clade V proteins B9-C2 PF07162.11 CDJ93536.1 - 1.7e-30 106.4 0.0 2.1e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein DUF2650 PF10853.8 CDJ93537.1 - 7.5e-10 38.4 2.6 1.5e-09 37.4 2.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2650) stn_TNFRSF12A PF12191.8 CDJ93537.1 - 0.12 12.5 0.7 0.42 10.8 0.7 1.7 1 1 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Homeodomain PF00046.29 CDJ93539.1 - 4.9e-23 80.7 4.9 8.2e-23 80.0 4.9 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ93539.1 - 0.0018 18.1 0.2 0.005 16.7 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 CDJ93539.1 - 0.057 12.9 0.1 0.098 12.1 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Prefoldin_2 PF01920.20 CDJ93540.1 - 5e-20 71.4 12.1 6.5e-20 71.1 12.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit Syntaxin_2 PF14523.6 CDJ93540.1 - 0.014 15.8 6.5 0.23 11.9 0.3 2.3 2 1 0 2 2 2 0 Syntaxin-like protein NYD-SP28_assoc PF14775.6 CDJ93540.1 - 0.024 14.7 2.2 0.024 14.7 2.2 1.8 2 0 0 2 2 2 0 Sperm tail C-terminal domain NPV_P10 PF05531.12 CDJ93540.1 - 0.064 13.7 0.6 0.064 13.7 0.6 1.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.11 CDJ93540.1 - 0.15 12.2 8.1 0.57 10.3 1.3 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Snf7 PF03357.21 CDJ93540.1 - 0.19 11.3 12.1 0.4 10.2 4.2 2.1 2 0 0 2 2 2 0 Snf7 tRNA_lig_CPD PF08302.11 CDJ93540.1 - 0.24 10.8 4.1 0.3 10.5 4.1 1.1 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain MIP-T3_C PF17749.1 CDJ93540.1 - 0.26 11.2 8.5 0.077 13.0 2.7 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region DUF1664 PF07889.12 CDJ93540.1 - 0.28 11.2 4.0 0.37 10.8 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Occludin_ELL PF07303.13 CDJ93540.1 - 0.54 11.0 11.1 12 6.7 11.1 2.1 1 1 0 1 1 1 0 Occludin homology domain DUF883 PF05957.13 CDJ93540.1 - 1.4 9.5 6.3 1.4 9.6 1.7 2.2 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) XhlA PF10779.9 CDJ93540.1 - 2.6 8.3 7.6 0.41 10.9 1.6 2.2 2 0 0 2 2 2 0 Haemolysin XhlA KapB PF08810.10 CDJ93541.1 - 1.2 9.3 4.4 0.6 10.3 0.2 2.6 3 0 0 3 3 3 0 Kinase associated protein B UCH PF00443.29 CDJ93542.1 - 2.5e-45 155.0 0.1 5.7e-45 153.8 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ93542.1 - 2e-09 37.5 0.5 8.3e-09 35.5 0.5 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Syntaxin_2 PF14523.6 CDJ93542.1 - 0.087 13.2 0.3 2.6 8.5 0.1 3.0 3 0 0 3 3 3 0 Syntaxin-like protein Bin3 PF06859.12 CDJ93543.1 - 4.1e-41 140.0 0.0 7.8e-41 139.1 0.0 1.5 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.6 CDJ93543.1 - 1e-09 38.5 0.0 1.6e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ93543.1 - 1.4e-09 37.9 0.0 1.4e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ93543.1 - 2.9e-09 37.5 0.0 4.3e-06 27.3 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ93543.1 - 2.2e-08 34.8 0.0 1.1e-07 32.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ93543.1 - 8.9e-08 32.7 0.0 6.6e-06 26.7 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CDJ93543.1 - 1e-05 25.1 0.0 2.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CDJ93543.1 - 8.3e-05 22.2 0.0 0.0017 17.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.19 CDJ93543.1 - 0.00043 20.1 0.0 0.011 15.5 0.0 2.4 3 0 0 3 3 3 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 CDJ93543.1 - 0.0028 17.6 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CDJ93543.1 - 0.0048 16.4 0.0 0.022 14.2 0.0 1.9 1 1 0 2 2 2 1 Putative methyltransferase Methyltransf_32 PF13679.6 CDJ93543.1 - 0.0066 16.4 0.4 0.033 14.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 CDJ93543.1 - 0.015 14.6 0.0 3.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 CDJ93543.1 - 0.16 11.3 0.0 0.44 9.8 0.0 1.7 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family zf-C2H2_4 PF13894.6 CDJ93544.1 - 3.5e-08 33.6 21.2 0.091 13.6 0.2 6.8 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CDJ93544.1 - 5.5e-08 32.8 21.9 0.0026 18.1 0.2 6.6 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_3 PF13878.6 CDJ93544.1 - 0.022 14.6 5.1 0.61 10.0 0.1 3.9 4 0 0 4 4 4 0 zinc-finger of acetyl-transferase ESCO zf-H2C2_5 PF13909.6 CDJ93544.1 - 0.23 11.3 0.1 0.23 11.3 0.1 3.5 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 CDJ93544.1 - 0.26 11.6 3.1 10 6.5 0.0 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding CpXC PF14353.6 CDJ93544.1 - 0.27 11.3 6.0 14 5.7 0.0 4.2 2 1 3 5 5 5 0 CpXC protein zf-met PF12874.7 CDJ93544.1 - 0.42 11.1 0.1 0.42 11.1 0.1 4.6 4 1 0 4 4 4 0 Zinc-finger of C2H2 type Nudix_N_2 PF14803.6 CDJ93544.1 - 0.43 10.5 9.8 12 5.9 1.7 4.2 4 0 0 4 4 4 0 Nudix N-terminal zf_C2H2_ZHX PF18387.1 CDJ93544.1 - 0.48 10.1 12.9 0.78 9.4 0.4 3.8 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain FYVE PF01363.21 CDJ93544.1 - 2.1 8.5 7.9 4.3 7.5 4.7 2.9 2 1 0 2 2 2 0 FYVE zinc finger zf-Di19 PF05605.12 CDJ93544.1 - 7.9 6.9 20.7 0.5 10.7 0.3 5.0 5 1 1 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding SH3_9 PF14604.6 CDJ93545.1 - 2.7e-22 78.3 0.7 2e-15 56.4 0.2 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 CDJ93545.1 - 1.8e-17 62.7 0.1 1.4e-13 50.2 0.0 2.2 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 CDJ93545.1 - 3.5e-11 42.6 0.1 1.4e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain RIX1 PF08167.12 CDJ93546.1 - 0.015 15.1 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis Dynein_attach_N PF15867.5 CDJ93546.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Dynein attachment factor N-terminus CreA PF05981.12 CDJ93546.1 - 0.12 12.4 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 CreA protein SSP160 PF06933.11 CDJ93547.1 - 0.036 12.3 18.4 0.035 12.3 18.4 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Transposase_22 PF02994.14 CDJ93549.1 - 0.044 14.0 0.2 0.12 12.5 0.2 1.8 1 0 0 1 1 1 0 L1 transposable element RBD-like domain DUF4342 PF14242.6 CDJ93549.1 - 9.5 6.3 6.9 27 4.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) TPR_1 PF00515.28 CDJ93550.1 - 4.1e-23 80.2 11.3 2.5e-10 39.7 0.5 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ93550.1 - 1.8e-18 65.1 9.7 9.2e-08 31.6 0.4 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ93550.1 - 3.8e-17 61.7 7.4 1.1e-06 28.2 0.6 3.6 2 1 1 3 3 3 3 TPR repeat SGTA_dimer PF16546.5 CDJ93550.1 - 1.7e-14 53.4 0.4 1.7e-14 53.4 0.4 2.2 2 0 0 2 2 2 1 Homodimerisation domain of SGTA TPR_8 PF13181.6 CDJ93550.1 - 6.9e-11 41.5 9.6 2.8e-06 27.1 0.3 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ93550.1 - 5.8e-10 38.5 3.0 5.9e-05 22.8 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ93550.1 - 2.6e-09 37.3 4.9 1.1e-08 35.2 2.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ93550.1 - 2e-08 34.4 1.7 0.015 16.0 0.1 4.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ93550.1 - 6.9e-08 33.0 7.1 9.2e-05 23.0 2.7 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ93550.1 - 4e-07 30.0 7.6 0.0077 16.5 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ93550.1 - 4.5e-06 27.1 10.0 6.5e-05 23.4 2.1 3.2 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_15 PF13429.6 CDJ93550.1 - 9.8e-06 25.0 1.0 0.003 16.8 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 CDJ93550.1 - 3.4e-05 23.2 4.0 0.14 11.7 0.2 3.3 3 0 0 3 3 3 1 SHNi-TPR TPR_10 PF13374.6 CDJ93550.1 - 0.00065 19.5 6.6 0.031 14.1 0.5 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ93550.1 - 0.017 15.2 5.9 0.29 11.2 0.6 2.8 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 CDJ93550.1 - 0.024 14.7 5.1 0.092 12.9 2.9 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat XPC-binding PF09280.11 CDJ93550.1 - 0.029 14.1 7.1 0.74 9.6 1.6 2.5 2 0 0 2 2 2 0 XPC-binding domain BTAD PF03704.17 CDJ93550.1 - 0.056 13.9 4.5 0.82 10.1 3.3 2.9 2 1 0 2 2 2 0 Bacterial transcriptional activator domain STI1 PF17830.1 CDJ93550.1 - 0.26 11.2 9.0 2.1 8.4 9.0 2.3 1 1 0 1 1 1 0 STI1 domain TPR_6 PF13174.6 CDJ93550.1 - 0.36 11.6 4.7 0.72 10.6 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat GerD PF17898.1 CDJ93550.1 - 0.4 10.6 3.0 0.88 9.5 1.2 2.5 2 1 0 2 2 2 0 Spore germination GerD central core domain MIT PF04212.18 CDJ93550.1 - 0.45 10.6 5.6 3 8.0 0.8 3.1 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain LRR_6 PF13516.6 CDJ93551.1 - 0.00011 21.9 1.0 0.085 13.0 0.0 4.4 5 0 0 5 5 5 1 Leucine Rich repeat Herpes_UL37_2 PF07413.11 CDJ93551.1 - 0.056 12.7 0.0 0.11 11.7 0.0 1.4 2 0 0 2 2 2 0 Betaherpesvirus immediate-early glycoprotein UL37 DUF4971 PF16341.5 CDJ93551.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4971) SH3_2 PF07653.17 CDJ93552.1 - 1.2e-10 40.9 0.0 2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain fn3 PF00041.21 CDJ93552.1 - 4.9e-06 26.8 4.0 0.017 15.4 0.8 3.5 2 1 0 2 2 2 2 Fibronectin type III domain SH3_9 PF14604.6 CDJ93552.1 - 3.4e-05 23.6 0.0 7.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDJ93552.1 - 0.01 15.4 0.0 0.024 14.2 0.0 1.7 1 1 0 1 1 1 0 SH3 domain Pur_ac_phosph_N PF16656.5 CDJ93552.1 - 0.04 14.5 0.4 0.15 12.6 0.0 2.1 2 1 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain DUF5447 PF17525.2 CDJ93552.1 - 0.13 12.8 0.4 1.7 9.2 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5447) ASC PF00858.24 CDJ93554.1 - 3.8e-27 95.3 3.1 7e-27 94.5 3.1 1.4 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel E1-E2_ATPase PF00122.20 CDJ93555.1 - 7.4e-38 129.9 0.0 1.9e-37 128.5 0.0 1.7 1 1 1 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.8 CDJ93555.1 - 2.4e-16 60.0 7.4 4.8e-16 59.0 4.1 2.9 2 1 0 2 2 2 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.26 CDJ93555.1 - 3.2e-06 26.7 0.0 6.4e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Mad3_BUB1_I_2 PF17014.5 CDJ93555.1 - 0.076 13.1 0.3 0.14 12.3 0.3 1.4 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein PI3_PI4_kinase PF00454.27 CDJ93559.1 - 2.7e-45 155.2 2.8 1e-44 153.3 0.6 2.7 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CDJ93559.1 - 6.7e-27 94.1 1.8 1.8e-26 92.7 1.8 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PX PF00787.24 CDJ93559.1 - 5.7e-10 39.2 1.8 1.6e-09 37.7 1.8 1.8 1 0 0 1 1 1 1 PX domain C2 PF00168.30 CDJ93559.1 - 4.3e-09 36.6 0.1 3.2e-08 33.8 0.0 2.4 2 0 0 2 2 2 1 C2 domain PI3K_rbd PF00794.18 CDJ93559.1 - 3.6e-08 33.5 0.0 9.6e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 CDJ93559.1 - 0.00013 21.9 0.1 0.00076 19.4 0.0 2.3 3 0 0 3 3 3 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 CDJ93559.1 - 0.0066 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) PRD PF00874.20 CDJ93559.1 - 0.11 12.8 3.4 0.55 10.6 0.2 2.7 2 0 0 2 2 2 0 PRD domain TAN PF11640.8 CDJ93559.1 - 0.35 11.0 2.2 0.63 10.2 1.1 1.9 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair TGF_beta PF00019.20 CDJ93560.1 - 4.6e-15 56.5 2.7 7.4e-15 55.8 0.9 1.8 1 1 1 2 2 2 1 Transforming growth factor beta like domain RB_B PF01857.20 CDJ93562.1 - 1.5e-23 83.3 0.7 1.5e-23 83.3 0.7 1.6 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain DUF1682 PF07946.14 CDJ93562.1 - 0.022 14.0 3.7 0.027 13.7 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) 7TM_GPCR_Srd PF10317.9 CDJ93564.1 - 4e-19 68.9 0.8 4.8e-19 68.7 0.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Str PF10326.9 CDJ93564.1 - 4.9e-06 26.1 0.4 5.8e-06 25.9 0.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srh PF10318.9 CDJ93564.1 - 1e-05 24.7 0.5 1.2e-05 24.5 0.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Srj PF10319.9 CDJ93564.1 - 0.0019 17.6 0.3 0.0021 17.4 0.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj RA PF00788.23 CDJ93566.1 - 2e-24 86.1 0.2 2.5e-16 60.1 0.1 2.1 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain Ras_bdg_2 PF14847.6 CDJ93566.1 - 0.08 13.3 0.1 0.43 11.0 0.1 2.2 1 1 1 2 2 2 0 Ras-binding domain of Byr2 HIT PF01230.23 CDJ93567.1 - 1.6e-32 112.1 0.0 2.2e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CDJ93567.1 - 1.4e-21 77.1 0.0 1.9e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Exo_endo_phos_2 PF14529.6 CDJ93569.1 - 0.024 14.5 0.0 0.047 13.5 0.0 1.5 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ93569.1 - 0.046 13.2 0.0 0.86 9.1 0.0 2.1 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Y_phosphatase PF00102.27 CDJ93570.1 - 2.1e-68 230.4 0.2 2.6e-68 230.1 0.2 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ93570.1 - 8.6e-05 22.4 0.1 0.00019 21.3 0.1 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 CDJ93570.1 - 0.025 14.2 0.1 0.081 12.5 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family Myotub-related PF06602.14 CDJ93570.1 - 0.067 12.1 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain PTPlike_phytase PF14566.6 CDJ93570.1 - 0.071 13.2 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 CDJ93570.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Pkinase PF00069.25 CDJ93571.1 - 1.2e-143 477.2 0.0 8.1e-71 238.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ93571.1 - 7.5e-78 261.4 0.0 2.6e-40 138.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDJ93571.1 - 5.1e-13 49.0 0.0 5.4e-07 29.2 0.0 3.0 3 1 0 3 3 3 2 Kinase-like Kdo PF06293.14 CDJ93571.1 - 1e-08 34.8 0.0 0.00039 19.9 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ93571.1 - 1.8e-07 31.3 0.0 0.065 13.1 0.0 3.4 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ93571.1 - 2.3e-07 29.9 0.1 0.0012 17.7 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase Pkinase_C PF00433.24 CDJ93571.1 - 3.2e-07 30.9 0.4 9.1e-07 29.5 0.4 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain YrbL-PhoP_reg PF10707.9 CDJ93571.1 - 8.6e-05 22.1 0.1 0.09 12.3 0.0 2.9 3 0 0 3 3 3 2 PhoP regulatory network protein YrbL FTA2 PF13095.6 CDJ93571.1 - 0.00016 21.3 0.1 0.73 9.4 0.0 3.3 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CDJ93571.1 - 0.00096 18.2 0.7 0.0083 15.1 0.2 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Choline_kinase PF01633.20 CDJ93571.1 - 0.0033 17.1 0.1 0.082 12.5 0.0 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase AAA_6 PF12774.7 CDJ93573.1 - 3.5e-103 345.0 1.7 3.9e-48 164.1 0.1 3.7 1 1 2 3 3 3 3 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDJ93573.1 - 1.3e-102 343.9 8.9 1.3e-102 343.9 8.9 3.9 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 CDJ93573.1 - 4.5e-38 131.2 8.3 4.5e-38 131.2 8.3 3.4 4 1 0 4 4 3 1 Dynein heavy chain, N-terminal region 1 AAA_5 PF07728.14 CDJ93573.1 - 1.6e-17 63.8 0.0 6.4e-13 48.9 0.0 3.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDJ93573.1 - 1.3e-05 25.6 1.7 0.42 11.0 0.0 4.6 3 1 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 CDJ93573.1 - 8.9e-05 22.9 0.1 0.079 13.4 0.0 4.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CDJ93573.1 - 0.0001 22.8 0.9 0.83 10.2 0.0 4.6 5 0 0 5 5 3 2 AAA domain AAA_30 PF13604.6 CDJ93573.1 - 0.00024 20.9 0.1 0.34 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 CDJ93573.1 - 0.00041 20.1 0.0 0.023 14.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CDJ93573.1 - 0.00049 20.4 4.5 2.6 8.3 0.0 5.1 6 0 0 6 6 5 2 AAA domain ABC_tran PF00005.27 CDJ93573.1 - 0.0021 18.6 0.2 0.07 13.6 0.0 3.7 3 0 0 3 3 2 1 ABC transporter AAA_7 PF12775.7 CDJ93573.1 - 0.0074 15.8 0.3 0.22 11.0 0.1 2.8 2 0 0 2 2 2 1 P-loop containing dynein motor region ATP_bind_1 PF03029.17 CDJ93573.1 - 0.0084 15.9 0.5 2.5 7.8 0.0 3.7 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 CDJ93573.1 - 0.01 16.1 0.0 5.5 7.2 0.0 3.5 3 0 0 3 3 2 1 AAA domain Adeno_IVa2 PF02456.15 CDJ93573.1 - 0.012 14.4 0.0 0.21 10.3 0.0 2.9 3 0 0 3 3 3 0 Adenovirus IVa2 protein RNA_helicase PF00910.22 CDJ93573.1 - 0.018 15.5 0.0 21 5.6 0.0 3.9 3 0 0 3 3 3 0 RNA helicase RsgA_GTPase PF03193.16 CDJ93573.1 - 0.018 14.9 3.1 0.026 14.4 0.0 2.7 3 0 0 3 3 3 0 RsgA GTPase AAA_29 PF13555.6 CDJ93573.1 - 0.13 12.0 0.0 0.85 9.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain HisKA PF00512.25 CDJ93573.1 - 0.43 10.7 2.2 3.8 7.6 0.3 3.5 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain AAA_33 PF13671.6 CDJ93573.1 - 1.3 9.2 4.6 3.6 7.8 0.0 3.9 4 1 0 4 4 3 0 AAA domain AAA_23 PF13476.6 CDJ93573.1 - 1.3 9.5 0.0 1.3 9.5 0.0 6.9 2 1 1 3 3 2 0 AAA domain AAA_9 PF12781.7 CDJ93574.1 - 2.3e-59 200.2 2.2 2.3e-59 200.2 2.2 4.4 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_8 PF12780.7 CDJ93574.1 - 1.2e-39 136.3 0.0 3.8e-39 134.6 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_heavy PF03028.15 CDJ93574.1 - 7.6e-36 122.8 0.1 2.4e-33 114.7 0.1 3.8 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 CDJ93574.1 - 2.5e-30 105.4 0.2 2.7e-29 102.1 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 CDJ93574.1 - 7.4e-29 100.8 17.1 2e-28 99.5 17.1 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 CDJ93574.1 - 1e-28 100.4 0.1 1e-28 100.4 0.1 2.4 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain FapA PF03961.13 CDJ93574.1 - 0.075 11.6 28.3 0.48 9.0 3.9 3.3 3 0 0 3 3 3 0 Flagellar Assembly Protein A ERM PF00769.19 CDJ93574.1 - 1.5 8.6 33.8 0.12 12.2 10.7 3.5 3 0 0 3 3 3 0 Ezrin/radixin/moesin family P3A PF08727.11 CDJ93574.1 - 2.2 7.7 3.8 6.9 6.1 0.0 3.3 4 0 0 4 4 4 0 Poliovirus 3A protein like Bac_DnaA PF00308.18 CDJ93574.1 - 2.3 8.0 9.8 1 9.1 0.1 3.9 5 0 0 5 5 5 0 Bacterial dnaA protein SNF2_N PF00176.23 CDJ93575.1 - 1.6e-62 211.3 0.0 3e-62 210.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ93575.1 - 5e-20 71.9 0.0 1.5e-19 70.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain VHS PF00790.19 CDJ93575.1 - 8.5e-17 61.3 0.4 2.4e-16 59.9 0.1 1.9 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.28 CDJ93575.1 - 2.6e-14 52.6 0.0 6.8e-14 51.2 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CDJ93575.1 - 9.3e-12 44.6 0.0 1.9e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CDJ93575.1 - 6e-09 35.5 0.0 1.3e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain ERCC3_RAD25_C PF16203.5 CDJ93575.1 - 8.4e-07 28.5 0.1 3e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase HDA2-3 PF11496.8 CDJ93575.1 - 0.00067 18.9 0.0 0.0027 16.9 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 UIM PF02809.20 CDJ93575.1 - 0.0014 18.4 4.0 0.0041 16.9 4.0 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif PRELI PF04707.14 CDJ93576.1 - 1.2e-51 174.7 0.0 1.6e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 PRELI-like family Rsm22 PF09243.10 CDJ93577.1 - 2e-43 148.6 0.0 3.3e-23 82.3 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 CDJ93577.1 - 1.7e-05 24.7 0.0 9.4e-05 22.3 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ93577.1 - 0.0099 15.7 0.0 0.03 14.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ93577.1 - 0.041 14.6 0.0 0.23 12.2 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ93577.1 - 0.11 13.2 0.0 0.59 10.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Pox_A_type_inc PF04508.12 CDJ93578.1 - 0.017 15.0 1.1 0.017 15.0 1.1 6.0 7 0 0 7 7 7 0 Viral A-type inclusion protein repeat Baculo_PEP_C PF04513.12 CDJ93578.1 - 5.4 7.1 24.5 0.69 9.9 1.2 5.2 3 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus SHE3 PF17078.5 CDJ93578.1 - 6.8 6.3 82.0 0.037 13.8 12.6 4.5 2 1 2 4 4 4 0 SWI5-dependent HO expression protein 3 DUF4988 PF16378.5 CDJ93578.1 - 7.7 6.1 6.5 12 5.5 0.1 3.7 2 1 1 3 3 3 0 Domain of unknown function ABC2_membrane_3 PF12698.7 CDJ93579.1 - 0.0095 15.1 0.9 0.015 14.5 0.9 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein Lectin_C PF00059.21 CDJ93582.1 - 3.2e-29 101.8 5.3 7.8e-19 68.4 0.7 2.2 2 0 0 2 2 2 2 Lectin C-type domain SAM_2 PF07647.17 CDJ93583.1 - 1.6e-20 73.0 0.5 1.9e-09 37.5 0.2 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CDJ93583.1 - 1.3e-13 51.2 0.7 3.6e-10 40.1 0.2 2.6 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) TIR_2 PF13676.6 CDJ93583.1 - 9.3e-11 42.4 0.0 1.7e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 CDJ93583.1 - 2.5e-05 24.2 0.0 4.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 TIR domain Malic_M PF03949.15 CDJ93584.1 - 6e-96 320.7 0.0 7.5e-96 320.3 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CDJ93584.1 - 1.1e-74 250.2 0.0 1.7e-74 249.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 CDJ93585.1 - 1.8e-95 319.1 0.0 2.4e-95 318.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CDJ93585.1 - 4.6e-76 254.7 0.0 7.1e-76 254.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Raffinose_syn PF05691.12 CDJ93585.1 - 0.16 9.7 0.0 0.24 9.1 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 NST1 PF13945.6 CDJ93586.1 - 0.24 11.5 6.1 0.29 11.2 6.1 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Peptidase_C1 PF00112.23 CDJ93587.1 - 2.7e-61 207.4 0.1 3.6e-61 207.0 0.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CDJ93587.1 - 5e-13 49.3 4.7 8.6e-13 48.5 4.7 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) DUF2206 PF09971.9 CDJ93587.1 - 0.022 13.5 0.1 0.032 13.0 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Peptidase_C1_2 PF03051.15 CDJ93587.1 - 0.26 10.0 6.9 0.73 8.5 0.5 2.7 3 0 0 3 3 3 0 Peptidase C1-like family Lectin_C PF00059.21 CDJ93588.1 - 2.4e-13 50.7 0.2 3.3e-13 50.3 0.2 1.2 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 CDJ93588.1 - 0.00021 21.0 0.0 0.00032 20.4 0.0 1.3 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like MIT_LIKE_ACTX PF17556.2 CDJ93588.1 - 0.12 13.0 0.2 0.32 11.6 0.2 1.8 1 0 0 1 1 1 0 MIT-like atracotoxin family NCD2 PF04905.13 CDJ93589.1 - 2.2e-50 169.8 0.1 3.7e-50 169.1 0.1 1.3 1 0 0 1 1 1 1 NAB conserved region 2 (NCD2) NCD1 PF04904.13 CDJ93589.1 - 1.9e-38 130.3 0.0 3.2e-38 129.6 0.0 1.4 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) DUF1505 PF07403.11 CDJ93590.1 - 0.066 13.4 0.1 0.077 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1505) Fungus-induced PF10917.8 CDJ93590.1 - 0.6 10.5 0.1 0.6 10.5 0.1 2.3 3 0 0 3 3 3 0 Fungus-induced protein AAA_30 PF13604.6 CDJ93591.1 - 1.1e-07 31.8 0.1 0.004 16.9 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 CDJ93591.1 - 1e-06 28.7 0.0 1.8e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ93591.1 - 1.1e-05 25.7 0.0 3.9e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 CDJ93591.1 - 0.016 15.1 0.1 2.5 7.9 0.1 2.4 2 0 0 2 2 2 0 Helicase ResIII PF04851.15 CDJ93591.1 - 0.17 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.16 CDJ93591.1 - 0.2 11.1 0.0 13 5.1 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein Mor PF08765.11 CDJ93593.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Mor transcription activator family FHA PF00498.26 CDJ93596.1 - 1.1e-10 41.7 0.1 1.8e-10 41.0 0.1 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CDJ93596.1 - 2.1e-06 28.0 0.0 5.8e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain APC_u13 PF16634.5 CDJ93596.1 - 0.042 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Unstructured region on APC between APC_crr and SAMP Y_phosphatase PF00102.27 CDJ93597.1 - 2.1e-79 266.4 0.0 3.5e-79 265.7 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase fn3 PF00041.21 CDJ93597.1 - 2.2e-31 108.0 2.8 3.8e-09 36.7 0.0 8.9 9 0 0 9 9 9 5 Fibronectin type III domain DSPc PF00782.20 CDJ93597.1 - 0.0038 17.0 0.0 0.015 15.1 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Pur_ac_phosph_N PF16656.5 CDJ93597.1 - 0.0063 17.1 0.0 16 6.2 0.0 4.0 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain DUF3010 PF11215.8 CDJ93598.1 - 2e-05 24.9 16.2 3.9 7.8 0.1 6.4 7 0 0 7 7 7 3 Protein of unknown function (DUF3010) Mak16 PF04874.14 CDJ93598.1 - 0.0046 17.5 38.3 0.12 13.0 1.1 7.8 8 0 0 8 8 8 4 Mak16 protein C-terminal region RXLR_WY PF18634.1 CDJ93598.1 - 0.0065 16.4 0.2 60 3.7 0.0 4.8 4 0 0 4 4 4 0 RXLR phytopathogen effector protein WY-domain DUF5638 PF18688.1 CDJ93598.1 - 0.02 15.2 0.2 4.5 7.6 0.0 4.4 5 0 0 5 5 5 0 Family of unknown function (DUF5638) PMBR PF09373.10 CDJ93598.1 - 0.07 13.3 0.0 0.41 10.9 0.0 2.3 2 0 0 2 2 2 0 Pseudomurein-binding repeat ATC_hydrolase PF14196.6 CDJ93598.1 - 0.24 12.2 16.5 5.3 7.8 0.1 6.1 7 0 0 7 7 7 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase DUF2788 PF10981.8 CDJ93598.1 - 1 9.4 4.8 1.3e+02 2.7 0.0 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF2788) His_Phos_2 PF00328.22 CDJ93599.1 - 1.1e-119 400.3 1.2 1.3e-119 399.9 1.2 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 CDJ93599.1 - 1.7e-26 92.1 0.6 5.1e-26 90.6 0.4 2.0 2 0 0 2 2 2 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 CDJ93599.1 - 0.0013 18.4 0.0 0.0045 16.6 0.0 1.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Capsule_synth PF05159.14 CDJ93600.1 - 0.044 13.2 2.4 0.054 12.9 2.4 1.2 1 0 0 1 1 1 0 Capsule polysaccharide biosynthesis protein eIF-4B PF06273.11 CDJ93600.1 - 0.34 9.9 11.7 0.42 9.6 11.7 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B CDC37_N PF03234.14 CDJ93600.1 - 0.7 10.8 11.7 1 10.3 11.7 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Mit_ribos_Mrp51 PF11709.8 CDJ93600.1 - 0.91 9.1 8.2 1 8.9 8.2 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit DUF5401 PF17380.2 CDJ93600.1 - 3.6 5.5 30.0 4.6 5.2 30.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Tox-ODYAM1 PF15642.6 CDJ93600.1 - 4.1 6.3 10.3 4.6 6.1 10.3 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus GDC-P PF02347.16 CDJ93601.1 - 2.7e-190 632.8 0.8 2e-180 600.2 0.1 2.6 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 CDJ93601.1 - 5.4e-05 22.3 0.1 0.051 12.5 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 CDJ93601.1 - 0.021 14.1 0.0 0.049 12.9 0.0 1.6 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 CDJ93601.1 - 0.049 12.1 0.0 0.19 10.2 0.0 1.9 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Ran_BP1 PF00638.18 CDJ93602.1 - 2e-13 50.6 0.1 4e-13 49.7 0.1 1.5 1 0 0 1 1 1 1 RanBP1 domain PP1c_bdg PF10488.9 CDJ93602.1 - 0.052 13.0 6.0 0.066 12.7 6.0 1.4 1 1 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region WH1 PF00568.23 CDJ93602.1 - 0.071 13.1 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 WH1 domain Spermine_synth PF01564.17 CDJ93603.1 - 0.00089 18.7 0.8 0.002 17.6 0.4 1.8 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Methyltransf_25 PF13649.6 CDJ93603.1 - 0.084 13.6 0.0 0.19 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Allexi_40kDa PF05549.11 CDJ93604.1 - 0.017 14.7 6.4 0.34 10.4 2.4 3.3 2 1 2 4 4 4 0 Allexivirus 40kDa protein DUF2205 PF10224.9 CDJ93604.1 - 0.034 14.1 1.4 0.034 14.1 1.4 2.2 2 0 0 2 2 2 0 Short coiled-coil protein ApoLp-III PF07464.11 CDJ93604.1 - 0.044 13.9 5.9 0.15 12.2 2.8 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) AATF-Che1 PF13339.6 CDJ93604.1 - 0.061 14.0 7.3 5.2 7.8 0.0 3.2 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor NPV_P10 PF05531.12 CDJ93604.1 - 0.075 13.5 4.1 15 6.2 0.1 3.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 CDJ93604.1 - 0.099 12.0 4.1 0.18 11.1 3.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF16 PF01519.16 CDJ93604.1 - 0.11 13.0 5.2 0.51 10.9 1.5 3.0 3 0 0 3 3 3 0 Protein of unknown function DUF16 PMT2_N PF17987.1 CDJ93604.1 - 0.11 12.7 0.1 1.7 8.9 0.0 2.2 2 0 0 2 2 2 0 Phosphoethanolamine N-methyltransferase 2 N-terminal DUF4611 PF15387.6 CDJ93604.1 - 0.16 12.2 6.0 1 9.6 4.8 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4611) Baculo_PEP_C PF04513.12 CDJ93604.1 - 0.26 11.3 5.5 6.3 6.8 2.2 2.9 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SKA2 PF16740.5 CDJ93604.1 - 0.34 10.7 6.2 0.62 9.9 2.5 3.1 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF1978 PF09321.10 CDJ93604.1 - 0.45 9.8 7.6 0.86 8.9 2.0 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF1978) DUF3763 PF12592.8 CDJ93604.1 - 0.71 10.0 4.9 3 8.0 4.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3763) Muted PF14942.6 CDJ93604.1 - 1.8 8.9 10.4 1.1 9.6 6.8 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DASH_Spc19 PF08287.11 CDJ93604.1 - 1.9 8.3 8.5 2 8.3 4.3 2.8 2 0 0 2 2 2 0 Spc19 CLZ PF16526.5 CDJ93604.1 - 2.1 8.8 8.4 3.8 7.9 0.5 4.1 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Apolipoprotein PF01442.18 CDJ93604.1 - 2.2 8.1 9.7 1.5 8.7 5.7 2.3 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain FlaC_arch PF05377.11 CDJ93604.1 - 2.6 8.5 6.9 2.8 8.4 0.4 3.5 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF2203 PF09969.9 CDJ93604.1 - 4 8.2 7.9 3.8 8.2 0.7 3.4 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2203) Syntaxin-6_N PF09177.11 CDJ93604.1 - 6.3 7.4 10.4 1.4 9.6 3.6 3.0 4 0 0 4 4 3 0 Syntaxin 6, N-terminal Ras PF00071.22 CDJ93605.1 - 4.7e-10 39.3 0.0 1e-08 35.0 0.0 2.1 1 1 0 1 1 1 1 Ras family FleQ PF06490.11 CDJ93605.1 - 0.0052 17.1 0.0 0.009 16.4 0.0 1.3 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ REF PF05755.12 CDJ93605.1 - 0.022 14.6 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) Collagen PF01391.18 CDJ93607.1 - 1.5e-23 82.3 73.9 1.3e-10 40.8 33.1 3.2 3 0 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ93607.1 - 1.8e-18 66.3 0.2 2.5e-18 65.8 0.2 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Oleosin PF01277.17 CDJ93607.1 - 0.095 12.5 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Oleosin Mitofilin PF09731.9 CDJ93608.1 - 0.0039 16.1 21.0 0.0051 15.7 21.0 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein MAP7 PF05672.11 CDJ93608.1 - 0.054 13.2 28.0 0.11 12.2 28.0 1.4 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Neur_chan_memb PF02932.16 CDJ93608.1 - 3.8 7.5 5.0 5.1 7.1 5.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region V_ATPase_I PF01496.19 CDJ93608.1 - 7.2 4.4 8.6 9.5 4.0 8.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LCD1 PF09798.9 CDJ93608.1 - 8 4.8 14.1 10 4.5 14.1 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein TPR_2 PF07719.17 CDJ93609.1 - 1.1e-34 115.7 5.7 0.00016 21.6 0.0 9.5 8 1 1 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ93609.1 - 2.1e-34 115.9 2.3 5.6e-07 29.1 0.0 9.7 10 0 0 10 10 10 4 Tetratricopeptide repeat DUF1736 PF08409.11 CDJ93609.1 - 6.6e-29 99.7 2.3 1.8e-28 98.3 2.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_11 PF13414.6 CDJ93609.1 - 2.8e-26 90.9 0.8 3e-07 30.0 1.1 7.0 5 2 2 7 7 7 5 TPR repeat TPR_8 PF13181.6 CDJ93609.1 - 5.3e-25 85.5 1.3 0.00018 21.5 0.0 8.8 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ93609.1 - 4e-24 84.7 13.4 3.9e-06 27.1 0.3 6.8 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ93609.1 - 1.9e-21 74.9 3.0 0.025 15.4 0.0 8.3 3 2 5 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ93609.1 - 6.2e-19 68.3 3.9 0.00043 20.7 0.1 5.7 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ93609.1 - 6.6e-18 63.7 11.2 0.018 15.4 0.2 9.5 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ93609.1 - 3.5e-17 62.8 4.2 0.00018 22.1 0.1 5.4 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ93609.1 - 2.1e-15 55.5 5.7 0.0013 18.6 0.0 8.6 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ93609.1 - 1.6e-13 50.0 17.1 0.012 15.5 1.5 8.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ93609.1 - 1.5e-09 37.8 2.6 0.93 10.3 0.0 7.8 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CDJ93609.1 - 7.5e-09 35.4 3.6 1.3e-06 28.0 2.9 3.3 2 1 1 3 3 3 1 MalT-like TPR region TPR_21 PF09976.9 CDJ93609.1 - 4.1e-08 33.2 4.9 0.017 14.8 0.0 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 CDJ93609.1 - 2.2e-05 24.5 1.1 0.041 14.0 0.0 3.9 3 1 2 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ93609.1 - 0.00091 19.4 8.4 0.44 10.8 0.6 4.8 2 1 3 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 Wzy_C_2 PF11846.8 CDJ93609.1 - 0.0026 17.7 2.3 8.4 6.3 0.0 4.3 2 1 1 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal TPR_15 PF13429.6 CDJ93609.1 - 0.004 16.4 4.9 2.3 7.3 0.1 3.9 2 1 1 4 4 4 2 Tetratricopeptide repeat PMT_2 PF13231.6 CDJ93609.1 - 0.0046 17.2 8.4 0.0046 17.2 8.4 2.4 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase EST1_DNA_bind PF10373.9 CDJ93609.1 - 0.012 15.1 3.4 0.072 12.6 0.5 2.5 2 0 0 2 2 2 0 Est1 DNA/RNA binding domain TPR_3 PF07720.12 CDJ93609.1 - 0.016 15.2 2.3 30 4.7 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Tcf25 PF04910.14 CDJ93609.1 - 0.019 14.1 0.1 0.045 12.8 0.1 1.6 1 1 0 1 1 1 0 Transcriptional repressor TCF25 Fis1_TPR_C PF14853.6 CDJ93609.1 - 0.12 12.4 0.4 18 5.5 0.1 3.1 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Defensin_1 PF00323.19 CDJ93609.1 - 0.16 12.5 4.0 0.47 11.1 4.0 1.8 1 0 0 1 1 1 0 Mammalian defensin HemY_N PF07219.13 CDJ93609.1 - 0.53 10.5 5.9 11 6.3 0.0 3.7 2 1 1 3 3 3 0 HemY protein N-terminus Laminin_G_2 PF02210.24 CDJ93610.1 - 2.8e-69 231.5 0.3 1.9e-24 86.6 0.0 4.3 4 0 0 4 4 4 4 Laminin G domain Laminin_G_1 PF00054.23 CDJ93610.1 - 2.1e-55 186.5 0.9 1.1e-22 80.7 0.0 5.1 4 1 0 4 4 4 4 Laminin G domain Laminin_G_3 PF13385.6 CDJ93610.1 - 3e-11 43.7 0.0 0.00016 21.8 0.0 3.7 4 0 0 4 4 4 2 Concanavalin A-like lectin/glucanases superfamily DUF1080 PF06439.11 CDJ93610.1 - 7.9e-05 22.8 0.0 0.00047 20.3 0.0 2.2 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1080) SAWADEE PF16719.5 CDJ93610.1 - 0.13 12.3 0.0 0.42 10.6 0.0 1.8 2 0 0 2 2 2 0 SAWADEE domain AAA PF00004.29 CDJ93611.1 - 3.3e-43 147.3 0.0 6.3e-43 146.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ93611.1 - 2.1e-11 43.4 0.3 5e-11 42.2 0.3 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CDJ93611.1 - 1.4e-08 34.5 0.4 3.3e-08 33.3 0.0 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 CDJ93611.1 - 4.9e-07 29.8 0.1 0.00014 21.8 0.0 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDJ93611.1 - 7.3e-07 29.7 0.2 0.00021 21.7 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CDJ93611.1 - 1.8e-06 28.3 1.4 0.0029 17.9 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 CDJ93611.1 - 1e-05 25.7 0.0 0.00012 22.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CDJ93611.1 - 2.9e-05 23.8 0.0 6.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CDJ93611.1 - 0.00029 21.4 0.0 0.0011 19.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain DUF815 PF05673.13 CDJ93611.1 - 0.00087 18.5 0.0 0.021 14.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 CDJ93611.1 - 0.0012 19.1 0.1 0.0064 16.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CDJ93611.1 - 0.0021 17.6 0.0 0.0044 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_11 PF13086.6 CDJ93611.1 - 0.0037 17.1 0.3 0.19 11.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain Prot_ATP_OB_N PF17758.1 CDJ93611.1 - 0.0068 16.0 0.2 0.024 14.3 0.0 1.9 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain Thymidylate_kin PF02223.17 CDJ93611.1 - 0.0072 16.0 0.1 1.7 8.3 0.0 2.5 2 0 0 2 2 2 1 Thymidylate kinase AAA_24 PF13479.6 CDJ93611.1 - 0.0072 16.1 0.0 0.023 14.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CDJ93611.1 - 0.0073 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 CDJ93611.1 - 0.0079 16.1 0.0 0.023 14.5 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CDJ93611.1 - 0.0087 16.4 0.0 0.022 15.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase TsaE PF02367.17 CDJ93611.1 - 0.0097 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 CDJ93611.1 - 0.012 15.0 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SMC_ScpA PF02616.14 CDJ93611.1 - 0.012 15.5 0.5 0.025 14.5 0.5 1.5 1 0 0 1 1 1 0 Segregation and condensation protein ScpA DivIC PF04977.15 CDJ93611.1 - 0.012 15.3 2.4 0.038 13.7 2.4 1.8 1 0 0 1 1 1 0 Septum formation initiator TIP49 PF06068.13 CDJ93611.1 - 0.018 14.3 0.0 0.037 13.2 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 CDJ93611.1 - 0.018 15.1 0.0 0.051 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 CDJ93611.1 - 0.034 14.3 0.7 1.4 9.0 0.0 2.8 2 1 1 3 3 3 0 Shikimate kinase ATPase_2 PF01637.18 CDJ93611.1 - 0.061 13.2 0.3 0.59 10.0 0.0 2.6 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea NACHT PF05729.12 CDJ93611.1 - 0.08 12.9 0.0 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 CDJ93611.1 - 0.1 12.8 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CDJ93611.1 - 0.12 11.9 0.1 0.42 10.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain DUF3225 PF11533.8 CDJ93612.1 - 0.11 12.2 0.0 6.2 6.5 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3225) SIR2 PF02146.17 CDJ93615.1 - 1.3e-53 181.5 0.0 1.7e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TIL PF01826.17 CDJ93616.1 - 7.6 6.9 58.6 1.2 9.5 14.5 3.4 3 0 0 3 3 3 0 Trypsin Inhibitor like cysteine rich domain Glyco_transf_25 PF01755.17 CDJ93617.1 - 0.04 13.8 0.0 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) ANAPC15 PF15243.6 CDJ93618.1 - 4.2 7.8 12.9 4.7 7.7 6.7 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 PALP PF00291.25 CDJ93619.1 - 3.8e-75 253.0 1.1 4.8e-75 252.7 1.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.25 CDJ93619.1 - 7.2e-05 22.5 0.2 0.00017 21.3 0.2 1.7 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 CDJ93619.1 - 0.00047 20.7 0.1 0.0013 19.2 0.1 1.8 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 CDJ93619.1 - 0.09 12.8 0.0 0.3 11.1 0.0 1.9 1 1 0 1 1 1 0 ACT domain BatD PF13584.6 CDJ93620.1 - 0.0062 15.4 0.0 0.0072 15.2 0.0 1.0 1 0 0 1 1 1 1 Oxygen tolerance MFS_1_like PF12832.7 CDJ93620.1 - 0.052 12.4 0.1 0.056 12.3 0.1 1.0 1 0 0 1 1 1 0 MFS_1 like family DUF4064 PF13273.6 CDJ93620.1 - 0.06 13.6 0.0 0.07 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Proteasome PF00227.26 CDJ93621.1 - 2.5e-27 95.6 0.0 3.3e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ93621.1 - 5.2e-14 51.6 0.1 8.3e-14 51.0 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RINGv PF12906.7 CDJ93622.1 - 3.9e-11 42.9 9.0 3.9e-11 42.9 9.0 1.7 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.6 CDJ93622.1 - 0.007 16.7 6.5 0.007 16.7 6.5 2.3 2 1 1 3 3 3 2 Ring finger domain zf-RING_4 PF14570.6 CDJ93622.1 - 1.3 8.8 5.7 4 7.3 5.7 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Methyltransf_31 PF13847.6 CDJ93623.1 - 1.1e-11 44.8 0.0 1.3e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ93623.1 - 6e-09 36.5 0.0 1e-08 35.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ93623.1 - 8.7e-08 32.2 0.0 1.1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ93623.1 - 1.7e-06 28.7 0.0 2.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ93623.1 - 2e-06 28.4 0.0 3.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ93623.1 - 0.00019 21.0 0.0 0.00028 20.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Pox_MCEL PF03291.16 CDJ93623.1 - 0.002 17.3 0.0 0.0031 16.7 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme MetW PF07021.12 CDJ93623.1 - 0.0023 17.5 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.14 CDJ93623.1 - 0.0088 15.5 0.1 0.017 14.5 0.1 1.6 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 CDJ93623.1 - 0.017 15.1 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain KH_6 PF15985.5 CDJ93624.1 - 3e-08 33.9 0.3 7.7e-08 32.6 0.1 1.8 2 0 0 2 2 2 1 KH domain ECR1_N PF14382.6 CDJ93624.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region DUF3886 PF13025.6 CDJ93624.1 - 0.027 14.7 0.9 0.045 13.9 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) S1 PF00575.23 CDJ93624.1 - 0.032 14.6 0.0 0.47 10.8 0.1 2.8 3 1 0 3 3 3 0 S1 RNA binding domain EXOSC1 PF10447.9 CDJ93624.1 - 0.06 14.0 2.0 0.31 11.7 0.1 2.8 2 2 1 3 3 3 0 Exosome component EXOSC1/CSL4 Pou PF00157.17 CDJ93625.1 - 2.9e-24 84.8 0.8 1.2e-23 82.9 0.4 2.0 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 CDJ93625.1 - 6.3e-15 54.8 3.7 1.8e-14 53.3 3.7 1.8 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 CDJ93625.1 - 0.01 16.2 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 CDJ93625.1 - 0.023 14.7 0.1 0.067 13.3 0.1 1.8 1 1 0 1 1 1 0 Helix-turn-helix HTH_19 PF12844.7 CDJ93625.1 - 0.075 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Pou PF00157.17 CDJ93626.1 - 4.4e-37 125.9 0.1 9.6e-37 124.8 0.1 1.5 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 CDJ93626.1 - 2.4e-18 65.7 3.3 6.2e-18 64.4 3.3 1.8 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 CDJ93626.1 - 0.0087 16.4 0.0 0.068 13.5 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain Myb_Cef PF11831.8 CDJ93627.1 - 3.5e-36 125.0 0.3 3.5e-36 125.0 0.3 3.7 3 1 1 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 CDJ93627.1 - 9.9e-20 70.5 6.2 8.5e-11 41.9 1.6 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ93627.1 - 1.5e-18 66.8 6.6 4.7e-12 46.0 3.1 3.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain GvpG PF05120.12 CDJ93627.1 - 0.05 13.6 4.8 1.7 8.7 2.0 4.0 2 1 1 3 3 3 0 Gas vesicle protein G DUF637 PF04830.13 CDJ93627.1 - 0.083 12.7 0.4 0.22 11.4 0.4 1.7 1 0 0 1 1 1 0 Possible hemagglutinin (DUF637) DUF3349 PF11829.8 CDJ93627.1 - 0.35 11.7 2.3 0.66 10.8 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) Fib_alpha PF08702.10 CDJ93627.1 - 0.59 10.3 5.2 2.3 8.4 5.2 2.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Rap1_C PF11626.8 CDJ93627.1 - 6.4 6.9 9.9 0.25 11.4 0.2 3.4 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Exo_endo_phos_2 PF14529.6 CDJ93628.1 - 0.01 15.7 0.0 0.026 14.3 0.0 1.7 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase MMR_HSR1_Xtn PF16897.5 CDJ93629.1 - 8.2e-44 148.0 1.2 1.4e-43 147.2 0.5 1.7 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CDJ93629.1 - 4.8e-21 74.6 0.1 9.8e-21 73.6 0.1 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CDJ93629.1 - 1.2e-05 25.3 0.0 5.5e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ93629.1 - 0.027 14.0 0.0 2.7 7.5 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain DDE_Tnp_1_7 PF13843.6 CDJ93632.1 - 7.6e-21 74.8 0.0 9.5e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 7tm_1 PF00001.21 CDJ93635.1 - 1.8e-48 165.2 24.5 2.6e-48 164.6 24.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ93635.1 - 1.3e-11 44.4 24.4 2e-11 43.8 24.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 CDJ93635.1 - 0.0052 16.5 21.6 0.0052 16.5 21.6 2.4 1 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 CDJ93635.1 - 0.065 13.0 17.1 0.081 12.6 13.0 2.5 2 1 0 2 2 2 0 Olfactory receptor Claudin_3 PF06653.11 CDJ93636.1 - 3.9e-05 23.7 6.3 4.3e-05 23.5 6.3 1.0 1 0 0 1 1 1 1 Tight junction protein, Claudin-like Claudin_2 PF13903.6 CDJ93636.1 - 0.024 14.4 6.2 0.025 14.4 6.2 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction CbtB PF09489.10 CDJ93636.1 - 1.5 9.0 6.3 11 6.2 1.2 2.2 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) SMP_2 PF10144.9 CDJ93636.1 - 2.1 8.0 4.6 1.1 8.9 0.2 1.9 2 0 0 2 2 2 0 Bacterial virulence factor haemolysin DUF4131 PF13567.6 CDJ93636.1 - 2.9 7.5 5.9 4.1 7.0 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Orf78 PF06024.12 CDJ93636.1 - 3.5 8.0 4.9 2.7 8.4 0.7 2.0 2 0 0 2 2 2 0 Orf78 (ac78) DUF2207 PF09972.9 CDJ93636.1 - 4.7 5.9 5.7 5.4 5.6 5.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MHC2-interact PF09307.10 CDJ93636.1 - 7.3 6.6 5.2 0.55 10.2 0.4 1.5 2 0 0 2 2 2 0 CLIP, MHC2 interacting Claudin_3 PF06653.11 CDJ93637.1 - 0.00079 19.4 0.8 0.00086 19.3 0.8 1.0 1 0 0 1 1 1 1 Tight junction protein, Claudin-like DUF2556 PF10831.8 CDJ93637.1 - 0.046 13.7 3.2 0.17 11.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2556) Ferric_reduct PF01794.19 CDJ93637.1 - 0.057 13.5 0.7 0.072 13.2 0.7 1.1 1 0 0 1 1 1 0 Ferric reductase like transmembrane component CcmD PF04995.14 CDJ93637.1 - 0.35 11.0 0.3 0.35 11.0 0.3 2.1 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF3951 PF13131.6 CDJ93637.1 - 0.42 10.8 5.0 4.8 7.5 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) SH3_9 PF14604.6 CDJ93638.1 - 2.8e-28 97.5 0.0 6.6e-13 48.3 0.0 4.3 4 0 0 4 4 4 4 Variant SH3 domain SH3_1 PF00018.28 CDJ93638.1 - 3.2e-24 84.3 0.0 1.1e-09 37.8 0.0 4.0 4 0 0 4 4 4 3 SH3 domain SH3_2 PF07653.17 CDJ93638.1 - 4.6e-13 48.6 0.1 1.4e-07 31.1 0.0 4.0 4 0 0 4 4 4 3 Variant SH3 domain RVT_1 PF00078.27 CDJ93639.1 - 2.5e-38 131.8 0.0 4.2e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDJ93639.1 - 0.00012 21.9 0.0 0.00034 20.4 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ93639.1 - 0.025 14.1 0.3 0.083 12.4 0.0 1.9 2 0 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family Neur_chan_LBD PF02931.23 CDJ93640.1 - 2.5e-42 144.8 3.3 3e-42 144.5 3.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ93640.1 - 1.7e-12 47.9 0.2 2.6e-12 47.3 0.2 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region RVT_1 PF00078.27 CDJ93641.1 - 1.1e-12 48.0 0.0 1.3e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3629 PF12302.8 CDJ93642.1 - 0.02 14.3 0.1 0.024 14.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) RVT_1 PF00078.27 CDJ93646.1 - 1.3e-09 37.9 0.0 2.1e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ELM2 PF01448.24 CDJ93647.1 - 0.01 16.6 0.2 0.016 15.9 0.2 1.3 1 0 0 1 1 1 0 ELM2 domain Acetyltransf_7 PF13508.7 CDJ93649.1 - 0.0026 18.2 0.0 0.0063 16.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDJ93649.1 - 0.0038 17.5 0.0 0.0074 16.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDJ93649.1 - 0.004 17.1 0.0 0.0097 15.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Astacin PF01400.24 CDJ93650.1 - 1.8e-05 24.4 0.4 0.01 15.5 0.0 2.3 1 1 1 2 2 2 2 Astacin (Peptidase family M12A) Cadherin PF00028.17 CDJ93651.1 - 1.2e-53 179.5 0.2 1.4e-11 44.6 0.0 5.5 5 0 0 5 5 5 5 Cadherin domain Cadherin_3 PF16184.5 CDJ93651.1 - 0.00062 19.7 0.0 0.034 14.2 0.0 3.1 2 0 0 2 2 2 1 Cadherin-like Cadherin_2 PF08266.12 CDJ93651.1 - 0.0025 17.6 0.0 4.9 7.1 0.0 4.1 5 0 0 5 5 5 1 Cadherin-like DZR PF12773.7 CDJ93653.1 - 0.0025 17.8 8.4 0.0073 16.3 0.6 2.6 3 0 0 3 3 3 2 Double zinc ribbon zf-ribbon_3 PF13248.6 CDJ93653.1 - 0.036 13.5 0.7 2.1 7.9 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-dskA_traR PF01258.17 CDJ93653.1 - 0.058 13.3 0.5 7.5 6.6 0.2 2.7 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger RNA_POL_M_15KD PF02150.16 CDJ93653.1 - 0.15 12.0 2.7 0.16 11.8 0.2 2.2 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Nudix_N_2 PF14803.6 CDJ93653.1 - 0.17 11.8 0.2 0.17 11.8 0.2 2.5 3 0 0 3 3 3 0 Nudix N-terminal PknG_rubred PF16919.5 CDJ93653.1 - 0.23 11.6 2.1 2.5 8.3 0.2 2.3 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain DZR PF12773.7 CDJ93654.1 - 0.0025 17.8 8.4 0.0073 16.3 0.6 2.6 3 0 0 3 3 3 2 Double zinc ribbon zf-ribbon_3 PF13248.6 CDJ93654.1 - 0.036 13.5 0.7 2.1 7.9 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-dskA_traR PF01258.17 CDJ93654.1 - 0.058 13.3 0.5 7.5 6.6 0.2 2.7 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger RNA_POL_M_15KD PF02150.16 CDJ93654.1 - 0.15 12.0 2.7 0.16 11.8 0.2 2.2 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Nudix_N_2 PF14803.6 CDJ93654.1 - 0.17 11.8 0.2 0.17 11.8 0.2 2.5 3 0 0 3 3 3 0 Nudix N-terminal PknG_rubred PF16919.5 CDJ93654.1 - 0.23 11.6 2.1 2.5 8.3 0.2 2.3 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain gag-asp_proteas PF13975.6 CDJ93655.1 - 0.037 14.6 0.1 0.29 11.7 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ93655.1 - 0.066 13.5 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ93655.1 - 0.084 13.5 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Rootletin PF15035.6 CDJ93656.1 - 8.9e-18 65.0 4.0 1.5e-17 64.3 4.0 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion MnmE_helical PF12631.7 CDJ93656.1 - 0.0054 16.9 0.5 0.0076 16.4 0.5 1.2 1 0 0 1 1 1 1 MnmE helical domain MukF_C PF17193.4 CDJ93656.1 - 0.014 15.6 0.7 1.1 9.4 0.3 2.1 2 0 0 2 2 2 0 MukF C-terminal domain UPF0449 PF15136.6 CDJ93656.1 - 1.4 9.4 5.2 0.63 10.5 1.2 2.3 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 FUSC PF04632.12 CDJ93656.1 - 1.7 7.1 6.5 7.7 4.9 1.8 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family DOMON PF03351.17 CDJ93657.1 - 1.1e-05 25.6 0.0 1.9e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 CDJ93657.1 - 1.8e-05 24.9 4.8 3.8e-05 23.8 4.8 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Silic_transp PF03842.13 CDJ93657.1 - 0.04 12.2 0.6 0.06 11.6 0.6 1.2 1 0 0 1 1 1 0 Silicon transporter Bac_A_amyl_C PF18612.1 CDJ93657.1 - 0.19 11.5 0.0 0.57 10.0 0.0 1.8 1 1 0 1 1 1 0 Bacterial Alpha amylase C-terminal domain DUF751 PF05421.11 CDJ93657.1 - 0.39 11.5 0.2 0.39 11.5 0.2 3.2 3 1 0 4 4 4 0 Protein of unknown function (DUF751) RT_RNaseH_2 PF17919.1 CDJ93658.1 - 3e-21 75.3 0.6 1e-10 41.5 0.1 3.2 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ93658.1 - 3.1e-21 75.9 0.0 5.1e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDJ93658.1 - 1.7e-16 60.4 0.1 3.8e-15 56.1 0.0 2.9 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 CDJ93658.1 - 7.3e-15 55.3 0.0 7.2e-06 26.5 0.0 2.5 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ93658.1 - 2.1e-11 44.3 0.0 0.0004 21.0 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease Integrase_H2C2 PF17921.1 CDJ93658.1 - 3.1e-07 30.4 0.0 7.8e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP PF00077.20 CDJ93658.1 - 0.00023 21.4 0.0 1.3 9.3 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease VWA_3 PF13768.6 CDJ93658.1 - 0.082 12.8 0.1 30 4.5 0.0 3.0 2 1 1 3 3 3 0 von Willebrand factor type A domain DNA_ligase_A_N PF04675.14 CDJ93658.1 - 0.11 12.8 0.4 4 7.7 0.1 3.3 4 0 0 4 4 4 0 DNA ligase N terminus Nup35_RRM PF05172.13 CDJ93659.1 - 1.4e-22 79.6 0.0 2.7e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 CDJ93659.1 - 3.9e-15 55.6 0.0 6.1e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif ASC PF00858.24 CDJ93660.1 - 3.1e-18 66.0 2.1 4e-18 65.6 2.1 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Aa_trans PF01490.18 CDJ93660.1 - 0.012 14.4 0.0 0.013 14.2 0.0 1.0 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein Folliculin_C PF16692.5 CDJ93661.1 - 1.4e-30 106.7 0.0 1.9e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Folliculin C-terminal domain Hydrolase_6 PF13344.6 CDJ93663.1 - 4.9e-24 84.4 0.0 1.2e-23 83.2 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CDJ93663.1 - 2.3e-19 69.2 0.0 3.9e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CDJ93663.1 - 3.1e-07 30.9 0.1 1e-05 25.9 0.1 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CDJ93663.1 - 6.6e-07 29.6 0.2 0.0011 19.1 0.0 3.0 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 CDJ93663.1 - 0.00032 20.3 0.0 0.0016 18.1 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase HAD PF12710.7 CDJ93663.1 - 0.0065 16.9 0.5 1 9.8 0.0 3.0 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDJ93663.1 - 0.086 12.6 0.0 4 7.1 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CDJ93664.1 - 5.5e-23 81.0 0.0 3.4e-22 78.4 0.0 2.1 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CDJ93664.1 - 9.8e-18 64.0 0.0 1.7e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CDJ93664.1 - 7.8e-09 36.1 0.0 2.9e-08 34.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 CDJ93664.1 - 1.7e-05 24.5 0.0 0.00049 19.7 0.0 2.3 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase HAD_2 PF13419.6 CDJ93664.1 - 2.4e-05 24.5 0.0 0.031 14.3 0.0 2.9 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Kelch_3 PF13415.6 CDJ93664.1 - 0.02 15.2 0.0 0.058 13.7 0.0 1.8 2 0 0 2 2 2 0 Galactose oxidase, central domain Hydrolase_3 PF08282.12 CDJ93664.1 - 0.058 13.1 0.0 9.5 5.9 0.0 2.3 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 CDJ93664.1 - 0.082 13.3 0.1 12 6.3 0.0 2.8 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CDJ93665.1 - 5.4e-26 90.7 0.0 2.3e-25 88.6 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CDJ93665.1 - 3.6e-17 62.2 0.0 7.2e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CDJ93665.1 - 1.7e-13 51.3 0.0 1.1e-12 48.6 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CDJ93665.1 - 2.6e-06 27.6 0.0 0.0071 16.4 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 CDJ93665.1 - 0.00024 20.8 0.0 0.0025 17.5 0.0 2.2 1 1 0 2 2 2 1 Mitochondrial PGP phosphatase HAD PF12710.7 CDJ93665.1 - 0.13 12.6 0.0 1.7 9.0 0.0 2.5 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase FAA_hydrolase PF01557.18 CDJ93666.1 - 1.2e-42 146.1 0.0 1.4e-42 145.9 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Arf PF00025.21 CDJ93667.1 - 2.3e-72 242.1 0.1 2.6e-72 241.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CDJ93667.1 - 1.8e-15 57.2 0.1 2.3e-15 56.8 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDJ93667.1 - 2.8e-14 53.0 0.0 3e-14 52.9 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CDJ93667.1 - 1.2e-12 47.7 0.0 1.4e-12 47.4 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CDJ93667.1 - 1.9e-11 43.8 0.0 2.4e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 CDJ93667.1 - 1.5e-10 40.8 1.9 1.7e-07 30.8 0.3 2.5 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 CDJ93667.1 - 0.00026 21.1 0.0 0.00039 20.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 CDJ93667.1 - 0.037 13.4 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 AIG1 family 6PF2K PF01591.18 CDJ93667.1 - 0.038 13.3 0.3 0.066 12.5 0.1 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase DUF2439 PF10382.9 CDJ93668.1 - 0.00021 21.6 0.0 0.00027 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) hSH3 PF14603.6 CDJ93668.1 - 0.11 12.9 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 Helically-extended SH3 domain DUF846 PF05832.12 CDJ93669.1 - 1.9e-47 160.8 10.9 2.6e-47 160.3 10.9 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) NRDE-2 PF08424.10 CDJ93670.1 - 3.7e-51 174.2 1.5 1.2e-50 172.5 0.5 2.1 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference FCH PF00611.23 CDJ93670.1 - 0.052 13.8 1.0 0.18 12.1 0.1 2.4 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain TonB_N PF16031.5 CDJ93670.1 - 0.092 13.3 6.8 0.19 12.2 6.8 1.4 1 0 0 1 1 1 0 TonB polyproline region NPR3 PF03666.13 CDJ93670.1 - 4.7 5.9 15.3 13 4.4 15.2 1.7 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Pkinase PF00069.25 CDJ93671.1 - 1.1e-45 156.1 0.0 1.3e-45 155.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ93671.1 - 1.2e-28 100.2 0.0 1.6e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ93671.1 - 0.00056 19.3 0.0 0.013 14.9 0.0 2.1 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 CDJ93671.1 - 0.1 12.2 0.1 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 RIO1 family G6PD_C PF02781.16 CDJ93672.1 - 2.8e-32 112.1 0.0 3e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain zf-C2H2_2 PF12756.7 CDJ93673.1 - 0.005 17.2 4.2 0.026 14.9 0.5 2.2 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) BIR PF00653.21 CDJ93673.1 - 0.013 16.1 2.7 0.12 13.0 2.5 2.1 1 1 1 2 2 2 0 Inhibitor of Apoptosis domain zf-BED PF02892.15 CDJ93673.1 - 0.021 14.9 4.0 0.22 11.6 0.3 2.6 1 1 1 2 2 2 0 BED zinc finger zf-TRAF PF02176.18 CDJ93673.1 - 0.031 15.0 1.9 0.059 14.1 1.9 1.5 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_9 PF16293.5 CDJ93673.1 - 0.048 13.5 0.3 2.4 8.0 0.2 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2HE PF16278.5 CDJ93673.1 - 0.12 12.9 3.6 1.3 9.5 0.2 2.8 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Yippee-Mis18 PF03226.14 CDJ93673.1 - 0.17 12.1 2.0 0.92 9.7 0.8 2.0 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2H2_12 PF18658.1 CDJ93673.1 - 0.44 10.2 2.7 1.7 8.3 2.6 2.0 1 1 1 2 2 2 0 Zinc-finger C2H2-type zf-C2H2 PF00096.26 CDJ93673.1 - 0.76 10.4 0.1 0.76 10.4 0.1 3.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ93673.1 - 0.85 10.2 0.1 0.85 10.2 0.1 2.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDJ93673.1 - 1.4 9.9 0.1 1.4 9.9 0.1 3.4 3 1 0 3 3 3 0 C2H2-type zinc finger MIP PF00230.20 CDJ93674.1 - 0.0019 17.9 9.2 0.023 14.4 3.8 2.2 1 1 0 2 2 2 2 Major intrinsic protein Neuralized PF07177.12 CDJ93675.1 - 1.6e-05 25.0 0.0 2.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Neuralized DUF4681 PF15732.5 CDJ93676.1 - 0.00087 19.6 0.6 0.0011 19.2 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4681) CT_C_D PF02682.16 CDJ93676.1 - 0.032 14.0 0.2 0.041 13.6 0.2 1.1 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D KIP1 PF07765.12 CDJ93676.1 - 0.097 12.8 1.0 0.15 12.2 1.0 1.4 1 0 0 1 1 1 0 KIP1-like protein DUF1741 PF08427.10 CDJ93676.1 - 0.099 12.3 2.7 0.12 12.0 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) zf-C3HC4_3 PF13920.6 CDJ93677.1 - 2.5e-12 46.5 9.3 2.5e-12 46.5 9.3 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ93677.1 - 2.1e-06 28.0 9.7 2.1e-06 28.0 9.7 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ93677.1 - 0.00012 21.8 11.4 0.00026 20.7 11.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDJ93677.1 - 0.00032 20.5 8.2 0.00068 19.5 8.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CDJ93677.1 - 0.31 11.0 10.2 0.74 9.8 10.2 1.7 1 0 0 1 1 1 0 zinc-RING finger domain HTH_32 PF13565.6 CDJ93678.1 - 0.0052 17.4 0.0 0.0089 16.6 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain RVT_1 PF00078.27 CDJ93679.1 - 1e-09 38.3 0.1 1.7e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_N PF13655.6 CDJ93679.1 - 0.075 13.3 0.3 0.32 11.3 0.1 2.0 2 0 0 2 2 2 0 N-terminal domain of reverse transcriptase PALP PF00291.25 CDJ93680.1 - 2e-52 178.4 0.7 2.4e-52 178.2 0.7 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT_4 PF13291.6 CDJ93681.1 - 6.8e-06 26.6 0.0 9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 CDJ93681.1 - 0.011 15.7 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 0 ACT domain ACT PF01842.25 CDJ93681.1 - 0.02 14.7 0.1 0.025 14.3 0.1 1.2 1 0 0 1 1 1 0 ACT domain DUF898 PF05987.13 CDJ93685.1 - 0.0011 18.1 1.6 0.0012 18.0 1.6 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) 7tm_1 PF00001.21 CDJ93685.1 - 0.021 14.1 9.8 0.033 13.5 9.8 1.3 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDJ93685.1 - 0.025 13.9 8.8 0.033 13.5 8.8 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw ACC_central PF08326.12 CDJ93686.1 - 1e-06 27.3 0.1 1e-06 27.3 0.1 1.6 2 0 0 2 2 2 1 Acetyl-CoA carboxylase, central region Pox_A3L PF05288.11 CDJ93686.1 - 0.1 12.6 0.1 2.2 8.3 0.0 2.7 3 0 0 3 3 3 0 Poxvirus A3L Protein AA_permease_2 PF13520.6 CDJ93687.1 - 4.8e-42 144.3 30.4 6.6e-42 143.8 30.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CDJ93687.1 - 4e-21 75.2 25.1 5.8e-21 74.6 25.1 1.2 1 0 0 1 1 1 1 Amino acid permease Myb_CC_LHEQLE PF14379.6 CDJ93688.1 - 0.0079 15.9 2.2 0.013 15.2 2.2 1.3 1 0 0 1 1 1 1 MYB-CC type transfactor, LHEQLE motif Spore_III_AB PF09548.10 CDJ93688.1 - 0.012 15.7 0.1 0.016 15.4 0.1 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) RIH_assoc PF08454.11 CDJ93688.1 - 0.014 15.2 0.3 0.021 14.6 0.3 1.3 1 0 0 1 1 1 0 RyR and IP3R Homology associated TolA_bind_tri PF16331.5 CDJ93688.1 - 0.03 14.4 1.3 0.048 13.7 1.3 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation Apo-CIII PF05778.12 CDJ93688.1 - 0.06 13.0 0.1 0.095 12.3 0.1 1.5 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) rve PF00665.26 CDJ93689.1 - 0.017 15.3 0.0 0.035 14.3 0.0 1.5 2 0 0 2 2 2 0 Integrase core domain PhoLip_ATPase_C PF16212.5 CDJ93691.1 - 5.1e-22 78.8 10.3 6.6e-22 78.5 10.3 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 CDJ93691.1 - 4.8e-12 46.6 0.1 2.3e-10 41.1 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDJ93691.1 - 3.6e-11 43.0 0.0 1.6e-08 34.5 0.0 2.8 2 1 1 3 3 3 2 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CDJ93691.1 - 0.00068 19.4 0.1 0.0031 17.3 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CDJ93691.1 - 0.084 13.3 0.0 2.6 8.4 0.0 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Na_sulph_symp PF00939.19 CDJ93692.1 - 5.6e-39 134.5 9.4 6.8e-39 134.2 9.4 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CDJ93692.1 - 1.3e-15 57.4 25.0 4.7e-14 52.3 1.7 2.1 1 1 1 2 2 2 2 Citrate transporter Pterin_4a PF01329.19 CDJ93692.1 - 0.045 13.9 0.0 0.12 12.6 0.0 1.7 1 1 1 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase EGF_CA PF07645.15 CDJ93693.1 - 2.9e-59 197.0 225.0 2.8e-06 27.4 3.3 19.6 19 0 0 19 19 19 15 Calcium-binding EGF domain EGF_3 PF12947.7 CDJ93693.1 - 1.7e-54 181.7 210.3 2.7e-07 30.6 2.8 19.7 18 2 1 19 19 19 15 EGF domain EGF PF00008.27 CDJ93693.1 - 2.2e-48 162.1 207.7 2.2e-06 27.8 1.1 20.3 19 1 0 19 19 19 17 EGF-like domain hEGF PF12661.7 CDJ93693.1 - 6.8e-46 153.4 183.0 2.7e-05 24.6 3.7 22.2 20 1 0 20 20 20 16 Human growth factor-like EGF VWA PF00092.28 CDJ93693.1 - 2e-42 145.4 0.0 3e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain FXa_inhibition PF14670.6 CDJ93693.1 - 1.2e-19 70.3 221.3 0.0016 18.7 4.7 19.7 18 1 1 19 19 19 14 Coagulation Factor Xa inhibitory site VWA_2 PF13519.6 CDJ93693.1 - 6e-16 59.0 0.0 1e-15 58.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Plasmod_Pvs28 PF06247.11 CDJ93693.1 - 4.9e-15 55.6 173.4 0.0018 18.5 2.1 19.4 18 1 1 19 19 19 11 Pvs28 EGF domain cEGF PF12662.7 CDJ93693.1 - 1.3e-12 47.4 151.8 0.0069 16.3 0.1 19.3 19 0 0 19 19 19 13 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 CDJ93693.1 - 1.7e-11 44.0 148.7 0.0035 17.4 2.8 17.3 17 0 0 17 17 17 11 MSP1 EGF domain 1 rve PF00665.26 CDJ93694.1 - 8.4e-25 87.3 0.0 2.5e-24 85.8 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ93694.1 - 4.1e-09 36.4 1.6 9.2e-09 35.3 1.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CDJ93694.1 - 5.9e-05 22.8 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS1595 PF12762.7 CDJ93694.1 - 0.028 14.4 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 ISXO2-like transposase domain RE_Bsp6I PF09504.10 CDJ93694.1 - 0.059 13.0 0.1 0.3 10.6 0.0 2.2 3 0 0 3 3 3 0 Bsp6I restriction endonuclease DSPc PF00782.20 CDJ93696.1 - 2.2e-27 95.5 0.0 2.6e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CDJ93696.1 - 3e-05 24.2 0.0 4.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 CDJ93696.1 - 0.00042 20.0 0.0 0.0005 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 CDJ93696.1 - 0.002 18.4 0.0 0.0039 17.5 0.0 1.5 2 0 0 2 2 2 1 Rit1 DUSP-like domain Y_phosphatase3 PF13350.6 CDJ93696.1 - 0.021 14.8 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 CDJ93696.1 - 0.021 14.4 0.1 0.04 13.5 0.0 1.6 1 1 1 2 2 2 0 Tyrosine phosphatase family DUF442 PF04273.13 CDJ93696.1 - 0.036 14.1 0.0 0.048 13.7 0.0 1.2 1 0 0 1 1 1 0 Putative phosphatase (DUF442) CDKN3 PF05706.12 CDJ93696.1 - 0.047 13.4 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF640 PF04852.12 CDJ93696.1 - 0.15 12.2 0.5 0.31 11.2 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF640) DSPn PF14671.6 CDJ93696.1 - 0.16 12.5 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half Vps16_C PF04840.12 CDJ93697.1 - 1.2e-07 31.1 0.7 0.00012 21.2 0.3 2.2 2 0 0 2 2 2 2 Vps16, C-terminal region Tim29 PF10171.9 CDJ93697.1 - 0.1 12.1 0.1 0.79 9.2 0.0 2.4 2 1 0 2 2 2 0 Translocase of the Inner Mitochondrial membrane 29 Helicase_C PF00271.31 CDJ93698.1 - 4.9e-10 39.7 0.1 9.1e-10 38.9 0.0 1.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain L_HMGIC_fpl PF10242.9 CDJ93700.1 - 0.0011 19.3 5.7 0.0014 18.8 5.7 1.1 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Phage_holin_3_6 PF07332.11 CDJ93700.1 - 0.0012 18.8 6.5 0.0016 18.4 6.5 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF3185 PF11381.8 CDJ93700.1 - 0.018 15.0 3.6 0.19 11.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF2206 PF09971.9 CDJ93700.1 - 0.029 13.2 0.1 0.033 12.9 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Transglut_prok PF09017.10 CDJ93700.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Microbial transglutaminase DUF2207 PF09972.9 CDJ93700.1 - 1.8 7.2 5.7 2.2 6.9 5.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF423 PF04241.15 CDJ93700.1 - 2.2 8.6 6.1 5 7.4 4.9 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF423) DUF973 PF06157.11 CDJ93700.1 - 3.1 6.8 8.2 4.2 6.3 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF3742 PF12553.8 CDJ93700.1 - 3.8 7.6 4.4 1.2 9.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3742) DUF2721 PF11026.8 CDJ93700.1 - 6.2 6.7 9.0 9.1 6.2 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Tetraspanin PF00335.20 CDJ93700.1 - 9.7 5.8 10.3 50 3.5 10.3 1.8 1 1 0 1 1 1 0 Tetraspanin family Motile_Sperm PF00635.26 CDJ93701.1 - 3.7e-16 58.9 0.0 6.9e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain RXLR PF16810.5 CDJ93701.1 - 0.069 13.6 0.4 0.13 12.7 0.4 1.4 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Shisa PF13908.6 CDJ93701.1 - 1 9.5 3.1 1.4 9.1 1.2 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator AdoMet_Synthase PF01941.19 CDJ93703.1 - 0.033 13.0 0.1 0.04 12.7 0.1 1.1 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) SRP14 PF02290.15 CDJ93703.1 - 0.046 14.1 0.3 0.052 13.9 0.3 1.1 1 0 0 1 1 1 0 Signal recognition particle 14kD protein Iso_dh PF00180.20 CDJ93704.1 - 0.00082 18.6 0.0 0.00084 18.6 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase BamHI PF02923.15 CDJ93704.1 - 0.12 12.1 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease BamHI DUF4816 PF16086.5 CDJ93705.1 - 0.8 9.7 0.0 0.8 9.7 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4816) SKA2 PF16740.5 CDJ93706.1 - 0.0049 16.6 0.4 0.007 16.1 0.4 1.3 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 EIAV_Rev PF11129.8 CDJ93706.1 - 0.026 14.7 0.1 0.034 14.3 0.1 1.2 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus FANCI_HD2 PF14680.6 CDJ93706.1 - 0.054 12.7 0.1 0.07 12.4 0.1 1.2 1 0 0 1 1 1 0 FANCI helical domain 2 Piwi PF02171.17 CDJ93707.1 - 0.038 13.2 0.2 0.045 13.0 0.2 1.1 1 0 0 1 1 1 0 Piwi domain RVT_1 PF00078.27 CDJ93709.1 - 1.3e-07 31.3 0.0 9.2e-07 28.6 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDJ93709.1 - 0.00017 21.7 0.0 0.00069 19.8 0.0 2.1 1 1 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ93709.1 - 0.00033 20.7 0.0 0.00098 19.2 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 CDJ93709.1 - 0.0057 16.9 0.0 0.025 14.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase POPLD PF08170.12 CDJ93709.1 - 3 8.3 4.8 67 3.9 3.7 2.9 2 0 0 2 2 2 0 POPLD (NUC188) domain eIF-3_zeta PF05091.12 CDJ93709.1 - 9.3 5.1 19.2 1.1 8.2 9.4 2.7 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF724 PF05266.14 CDJ93710.1 - 0.065 13.1 1.2 0.078 12.8 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 CDJ93710.1 - 0.1 11.9 4.3 0.13 11.6 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HalX PF08663.10 CDJ93710.1 - 1.4 9.3 9.3 1.3 9.4 4.0 2.1 2 0 0 2 2 2 0 HalX domain Gal-bind_lectin PF00337.22 CDJ93711.1 - 4.2e-54 181.7 0.0 1.6e-26 92.5 0.0 2.1 2 0 0 2 2 2 2 Galactoside-binding lectin MFS_1 PF07690.16 CDJ93712.1 - 2.9e-15 56.1 5.5 2.5e-10 39.8 1.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5090 PF17009.5 CDJ93712.1 - 0.1 12.5 0.1 0.1 12.5 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5090) TatC PF00902.18 CDJ93712.1 - 0.42 10.4 9.0 0.36 10.6 7.5 1.6 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) Peptidase_U4 PF03419.13 CDJ93712.1 - 1.2 8.4 7.5 1.7 7.8 7.5 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Metallophos PF00149.28 CDJ93714.1 - 3.7e-33 115.7 0.0 5.1e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LRR_8 PF13855.6 CDJ93715.1 - 1e-78 259.0 73.5 6.7e-14 51.4 4.3 12.0 7 2 2 11 11 11 11 Leucine rich repeat LRR_4 PF12799.7 CDJ93715.1 - 1.4e-42 143.0 83.0 1.6e-05 25.2 6.8 17.0 6 5 7 17 17 17 14 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDJ93715.1 - 3e-24 85.5 31.3 1.9e-08 34.0 0.1 7.6 2 2 5 8 8 8 6 Leucine-rich repeat LRR_5 PF13306.6 CDJ93715.1 - 4.4e-20 71.9 2.9 4.3e-08 33.2 0.1 5.8 4 1 1 6 6 6 4 BspA type Leucine rich repeat region (6 copies) TIR_2 PF13676.6 CDJ93715.1 - 8.1e-10 39.3 0.0 2.6e-09 37.7 0.0 1.9 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 CDJ93715.1 - 6.6e-05 22.8 0.1 0.00012 22.0 0.1 1.3 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.33 CDJ93715.1 - 0.0002 21.5 80.0 10 7.1 1.3 22.0 23 4 1 24 24 24 2 Leucine Rich Repeat DUF1863 PF08937.11 CDJ93715.1 - 0.022 15.1 0.1 0.15 12.4 0.1 2.3 2 1 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) DUF5527 PF17665.1 CDJ93715.1 - 0.058 12.9 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5527) LRR_6 PF13516.6 CDJ93715.1 - 0.064 13.3 62.9 2.5 8.4 1.1 16.9 20 0 0 20 20 20 0 Leucine Rich repeat Pkinase_Tyr PF07714.17 CDJ93716.1 - 1.1e-77 260.8 0.0 7.7e-75 251.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CDJ93716.1 - 3.6e-44 151.1 0.0 6.8e-44 150.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDJ93716.1 - 6.4e-14 51.8 0.9 1.5e-13 50.7 0.9 1.7 1 0 0 1 1 1 1 SH2 domain Kinase-like PF14531.6 CDJ93716.1 - 0.0028 17.0 0.0 0.0062 15.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like ATPgrasp_N PF18130.1 CDJ93716.1 - 0.056 14.0 0.0 2.8 8.6 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp N-terminal domain CUB PF00431.20 CDJ93717.1 - 1.9e-72 240.6 0.6 6.7e-19 68.3 0.0 5.6 6 0 0 6 6 6 5 CUB domain Ldl_recept_a PF00057.18 CDJ93717.1 - 0.0003 20.9 9.2 0.00082 19.5 9.2 1.8 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A LIM PF00412.22 CDJ93718.1 - 4e-08 33.3 9.4 8e-08 32.4 9.4 1.5 1 0 0 1 1 1 1 LIM domain Adaptin_N PF01602.20 CDJ93719.1 - 1.1e-133 446.6 5.5 1.3e-133 446.3 5.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 CDJ93719.1 - 1.2e-20 73.9 0.1 2.5e-20 72.8 0.1 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 CDJ93719.1 - 1.6e-11 44.6 4.6 1.8e-07 31.4 0.4 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDJ93719.1 - 0.0041 17.5 0.5 11 6.5 0.0 5.0 4 2 2 6 6 6 1 HEAT repeats DUF5578 PF17741.1 CDJ93719.1 - 0.76 9.1 4.3 1.3 8.4 0.2 2.9 3 1 0 3 3 3 0 Family of unknown function (DUF5578) Collagen PF01391.18 CDJ93720.1 - 1.3e-21 76.1 113.8 7.1e-05 22.5 10.9 4.3 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ93720.1 - 5.7e-19 67.9 1.0 7.1e-19 67.6 1.0 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Proteasome PF00227.26 CDJ93721.1 - 3.4e-47 160.4 0.0 4.2e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ93721.1 - 2.7e-12 46.1 0.1 6.1e-12 45.0 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Flg_hook PF02120.16 CDJ93721.1 - 0.21 11.5 1.7 19 5.2 0.1 3.0 2 1 1 3 3 3 0 Flagellar hook-length control protein FliK fn3 PF00041.21 CDJ93722.1 - 8.3e-30 103.0 6.7 8e-08 32.5 0.3 4.2 4 0 0 4 4 4 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CDJ93722.1 - 7e-07 29.7 4.7 0.06 13.9 0.4 3.5 3 0 0 3 3 3 3 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 CDJ93722.1 - 0.00011 22.5 0.4 0.12 12.7 0.0 3.5 3 1 1 4 4 4 2 Interferon-alpha/beta receptor, fibronectin type III CAP PF00188.26 CDJ93723.1 - 3e-14 53.9 13.0 4.7e-09 37.1 1.2 3.0 3 1 0 3 3 3 2 Cysteine-rich secretory protein family Prion PF00377.18 CDJ93723.1 - 1.3 8.8 5.2 16 5.4 0.7 2.4 2 0 0 2 2 2 0 Prion/Doppel alpha-helical domain TrkA_TMD PF18613.1 CDJ93723.1 - 1.4 8.4 4.1 20 4.7 0.3 2.3 2 0 0 2 2 2 0 Tyrosine kinase receptor A trans-membrane domain TFIIA PF03153.13 CDJ93723.1 - 2.4 8.1 12.3 3 7.7 12.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nucleoporin_N PF08801.11 CDJ93724.1 - 8.6e-54 182.9 0.2 1.3e-53 182.4 0.2 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Motile_Sperm PF00635.26 CDJ93725.1 - 1.4e-18 66.7 0.2 2e-18 66.2 0.2 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain PapD-like PF14874.6 CDJ93725.1 - 0.00021 21.4 0.0 0.00027 21.0 0.0 1.2 1 0 0 1 1 1 1 Flagellar-associated PapD-like DUF1573 PF07610.11 CDJ93725.1 - 0.007 16.4 0.3 0.017 15.1 0.2 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1573) PapD_N PF00345.20 CDJ93725.1 - 0.025 14.5 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain ASH PF15780.5 CDJ93725.1 - 0.089 13.0 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Peptidase_S8 PF00082.22 CDJ93726.1 - 2.9e-42 144.9 3.2 4e-42 144.5 3.2 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 CDJ93726.1 - 1.2e-23 83.0 0.0 2.2e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 CDJ93726.1 - 1.4e-19 70.7 3.0 2.5e-19 69.8 3.0 1.5 1 0 0 1 1 1 1 Peptidase S8 pro-domain Xan_ur_permease PF00860.20 CDJ93727.1 - 7.2e-50 169.8 18.1 8.5e-50 169.6 18.1 1.0 1 0 0 1 1 1 1 Permease family Sugar_tr PF00083.24 CDJ93728.1 - 3.3e-14 52.6 1.4 4.3e-14 52.2 1.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ93728.1 - 1.1e-05 24.5 13.3 0.00019 20.5 13.3 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 CDJ93728.1 - 0.82 8.2 11.2 0.23 10.0 6.0 2.1 2 0 0 2 2 2 0 MFS/sugar transport protein TPR_19 PF14559.6 CDJ93730.1 - 3.6e-19 69.0 5.0 0.00011 22.7 0.0 6.6 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ93730.1 - 1.7e-14 52.6 18.5 0.019 15.0 0.1 9.0 11 0 0 11 11 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ93730.1 - 3.3e-10 40.0 19.7 0.00032 20.9 0.8 6.4 4 2 2 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CDJ93730.1 - 1.1e-09 38.4 10.9 0.026 14.8 1.1 7.4 5 3 4 9 9 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ93730.1 - 1.3e-07 32.1 3.4 0.00026 21.6 0.0 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ93730.1 - 9.4e-07 28.4 13.5 0.55 10.1 0.1 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ93730.1 - 0.0001 22.2 4.0 5.3 7.5 0.0 6.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ93730.1 - 0.00016 22.2 4.9 4.8 8.3 0.0 6.9 6 3 2 8 8 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ93730.1 - 0.00035 21.0 13.8 0.46 11.2 0.1 6.4 7 0 0 7 7 5 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CDJ93730.1 - 0.00059 19.8 13.0 0.31 11.1 0.2 5.1 3 1 2 5 5 5 1 Putative TPR-like repeat HrpB1_HrpK PF09613.10 CDJ93730.1 - 0.0016 18.1 0.0 2.6 7.7 0.0 3.7 4 0 0 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_7 PF13176.6 CDJ93730.1 - 0.005 16.8 11.4 3.1 8.0 0.0 6.7 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ93730.1 - 0.0079 16.0 3.8 21 5.2 0.0 5.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TAP_C PF03943.13 CDJ93730.1 - 0.026 14.2 4.2 9.8 5.9 0.1 4.5 4 0 0 4 4 4 0 TAP C-terminal domain Fis1_TPR_C PF14853.6 CDJ93730.1 - 0.027 14.6 0.1 0.027 14.6 0.1 5.0 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 CDJ93730.1 - 0.037 14.4 4.0 0.41 11.0 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 CDJ93730.1 - 0.08 13.6 0.0 11 7.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat BEX PF04538.12 CDJ93730.1 - 0.11 13.1 0.5 0.86 10.2 0.0 2.2 2 0 0 2 2 2 0 Brain expressed X-linked like family TPR_11 PF13414.6 CDJ93730.1 - 0.4 10.4 12.0 0.24 11.1 0.7 4.3 4 1 1 5 5 5 0 TPR repeat MOSC PF03473.17 CDJ93731.1 - 4.5e-28 97.9 0.0 8.1e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 CDJ93731.1 - 2.1e-27 95.4 0.0 3.1e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Motile_Sperm PF00635.26 CDJ93732.1 - 1.9e-05 24.5 0.0 3.7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain TTR-52 PF01060.23 CDJ93733.1 - 1.5e-13 51.3 0.0 2e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Transthyretin-like family Dimer_Tnp_hAT PF05699.14 CDJ93735.1 - 0.00016 21.4 0.0 0.00044 20.0 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TAN PF11640.8 CDJ93735.1 - 0.062 13.4 0.1 0.41 10.8 0.0 2.5 3 0 0 3 3 3 0 Telomere-length maintenance and DNA damage repair zf-BED PF02892.15 CDJ93736.1 - 1.8e-12 47.1 1.3 3.7e-12 46.1 1.3 1.6 1 0 0 1 1 1 1 BED zinc finger NPF PF16601.5 CDJ93736.1 - 0.065 13.7 2.5 0.63 10.5 1.2 2.7 2 1 0 2 2 2 0 Rabosyn-5 repeating NPF sequence-motif RTTN_N PF14726.6 CDJ93737.1 - 0.0072 17.1 0.2 7.2 7.5 0.0 2.9 2 0 0 2 2 2 2 Rotatin, an armadillo repeat protein, centriole functioning U3snoRNP10 PF12397.8 CDJ93737.1 - 0.1 13.0 1.6 0.23 11.8 1.6 1.6 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 LRR_4 PF12799.7 CDJ93737.1 - 8.1 7.0 9.6 25 5.4 0.9 4.5 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) NHL PF01436.21 CDJ93738.1 - 5.9e-05 22.9 0.0 4.4 7.5 0.0 4.6 4 0 0 4 4 4 2 NHL repeat SGL PF08450.12 CDJ93738.1 - 0.00076 19.1 0.0 0.0032 17.1 0.0 2.0 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region CCDC73 PF15818.5 CDJ93738.1 - 0.056 11.3 0.0 0.074 10.9 0.0 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 73 family ILEI PF15711.5 CDJ93739.1 - 5.9e-15 55.5 0.0 8.1e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Interleukin-like EMT inducer Nramp PF01566.18 CDJ93740.1 - 5e-118 394.2 11.0 5e-118 394.2 11.0 1.7 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein RNase_Zc3h12a PF11977.8 CDJ93741.1 - 4.2e-16 59.1 0.0 5.1e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Guanylate_cyc PF00211.20 CDJ93742.1 - 8e-107 354.8 1.2 1.8e-52 177.6 0.1 2.9 2 1 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF1053 PF06327.14 CDJ93742.1 - 0.043 14.4 0.0 0.16 12.6 0.0 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) Wzy_C_2 PF11846.8 CDJ93743.1 - 0.073 13.0 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal DcpS_C PF11969.8 CDJ93744.1 - 0.017 15.6 0.1 0.041 14.4 0.1 1.7 1 1 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding PCMT PF01135.19 CDJ93745.1 - 5e-76 255.1 0.0 7e-76 254.6 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 CDJ93745.1 - 5.4e-10 39.3 0.0 8.3e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ93745.1 - 6e-08 33.3 0.0 1.2e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ93745.1 - 1.7e-06 28.6 0.0 3.4e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ93745.1 - 4.5e-05 23.1 0.0 7.8e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 CDJ93745.1 - 8.3e-05 22.1 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 CDJ93745.1 - 0.00024 21.1 0.1 0.00038 20.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ93745.1 - 0.00027 20.3 0.0 0.00035 20.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 CDJ93745.1 - 0.00053 19.9 0.1 0.0031 17.4 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.17 CDJ93745.1 - 0.00069 18.9 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_16 PF10294.9 CDJ93745.1 - 0.0014 18.4 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Met_10 PF02475.16 CDJ93745.1 - 0.012 15.4 0.0 0.017 14.9 0.0 1.4 1 1 0 1 1 1 0 Met-10+ like-protein DOT1 PF08123.13 CDJ93745.1 - 0.018 14.6 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 GCD14 PF08704.10 CDJ93745.1 - 0.022 14.5 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_24 PF13578.6 CDJ93745.1 - 0.022 15.8 0.0 0.14 13.2 0.0 2.3 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ93745.1 - 0.047 14.4 0.0 0.18 12.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.7 CDJ93745.1 - 0.11 12.4 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain CAP_GLY PF01302.25 CDJ93746.1 - 3e-23 81.6 3.0 3.6e-23 81.3 3.0 1.1 1 0 0 1 1 1 1 CAP-Gly domain SCP-1 PF05483.12 CDJ93747.1 - 0.0012 17.0 0.0 0.0018 16.4 0.0 1.1 1 0 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) SERTA PF06031.13 CDJ93747.1 - 0.014 15.1 1.8 0.024 14.3 1.8 1.4 1 0 0 1 1 1 0 SERTA motif DUF2631 PF10939.8 CDJ93747.1 - 0.078 12.8 0.3 0.17 11.8 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2631) Sacchrp_dh_NADP PF03435.18 CDJ93748.1 - 4.1e-10 40.0 0.1 6.6e-10 39.4 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF4440 PF14534.6 CDJ93749.1 - 8.1e-10 39.1 0.0 1e-09 38.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 CDJ93749.1 - 2.3e-07 31.1 0.0 2.9e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 CDJ93749.1 - 7.3e-05 23.4 0.0 8.9e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4783 PF16022.5 CDJ93749.1 - 0.0003 20.9 0.0 0.00039 20.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4783) SnoaL PF07366.12 CDJ93749.1 - 0.0023 17.7 0.0 0.003 17.4 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase NTF2 PF02136.20 CDJ93749.1 - 0.046 14.3 0.0 0.047 14.3 0.0 1.1 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Spectrin_like PF18373.1 CDJ93749.1 - 0.086 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Spectrin like domain FliG_N PF14842.6 CDJ93749.1 - 0.18 12.4 0.1 4 8.0 0.1 2.1 1 1 1 2 2 2 0 FliG N-terminal domain DUF4440 PF14534.6 CDJ93750.1 - 8.5e-10 39.0 0.0 9.8e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 CDJ93750.1 - 6.4e-07 29.7 0.0 7.6e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 CDJ93750.1 - 0.0011 19.5 0.0 0.0014 19.3 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4783 PF16022.5 CDJ93750.1 - 0.0017 18.5 0.1 0.0023 18.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4783) SnoaL PF07366.12 CDJ93750.1 - 0.011 15.6 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase SnoaL_4 PF13577.6 CDJ93750.1 - 0.023 14.8 0.2 0.033 14.3 0.2 1.3 1 1 0 1 1 1 0 SnoaL-like domain Toxin_20 PF08089.11 CDJ93750.1 - 0.038 14.1 0.3 0.074 13.2 0.3 1.4 1 0 0 1 1 1 0 Huwentoxin-II family SnoaL_2 PF12680.7 CDJ93751.1 - 0.0024 18.5 0.0 0.0027 18.3 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 CDJ93751.1 - 0.0036 17.7 0.0 0.0042 17.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.12 CDJ93751.1 - 0.0049 16.7 0.0 0.0054 16.5 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_3 PF13474.6 CDJ93751.1 - 0.014 15.7 0.0 0.017 15.4 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain SnoaL_4 PF13577.6 CDJ93751.1 - 0.063 13.4 0.0 0.063 13.4 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain NTF2 PF02136.20 CDJ93751.1 - 0.092 13.3 0.0 0.11 13.1 0.0 1.2 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Vpu PF00558.19 CDJ93752.1 - 2.2 8.1 6.2 14 5.5 6.2 2.1 1 1 0 1 1 1 0 Vpu protein SF3b1 PF08920.10 CDJ93753.1 - 8e-45 152.2 20.7 3.1e-41 140.6 1.1 4.7 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 CDJ93753.1 - 8.2e-10 38.9 4.8 0.94 9.9 0.0 7.3 4 2 4 8 8 8 2 HEAT repeats HEAT PF02985.22 CDJ93753.1 - 6.5e-09 35.3 11.0 0.12 12.7 0.0 8.7 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.6 CDJ93753.1 - 8.5e-08 32.5 10.0 0.97 10.0 0.0 8.0 9 1 1 10 10 9 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CDJ93753.1 - 1.4e-05 25.6 2.0 2.5 8.7 0.0 5.6 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CDJ93753.1 - 0.00021 21.4 5.8 0.84 9.7 0.0 5.5 5 1 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 CDJ93753.1 - 0.001 18.3 0.0 11 5.0 0.0 4.2 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 CDJ93753.1 - 0.0034 17.0 0.8 3.7 7.0 0.1 3.4 4 0 0 4 4 4 2 CLASP N terminal Adaptin_N PF01602.20 CDJ93753.1 - 0.0043 15.7 0.2 0.14 10.6 0.1 2.9 1 1 0 1 1 1 1 Adaptin N terminal region Dopey_N PF04118.14 CDJ93753.1 - 0.005 16.0 0.8 0.27 10.3 0.1 3.6 2 1 2 4 4 4 1 Dopey, N-terminal UNC45-central PF11701.8 CDJ93753.1 - 0.014 15.4 0.0 0.049 13.6 0.0 1.9 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central NUC173 PF08161.12 CDJ93753.1 - 0.014 15.1 0.2 1.1 8.9 0.0 3.8 5 0 0 5 5 5 0 NUC173 domain CDH PF02611.15 CDJ93753.1 - 0.16 11.5 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase DNA_pol_phi PF04931.13 CDJ93753.1 - 4.3 5.3 4.3 15 3.5 0.0 2.5 3 0 0 3 3 3 0 DNA polymerase phi IML1 PF12257.8 CDJ93754.1 - 3.3e-93 311.9 0.3 5e-93 311.3 0.3 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 CDJ93754.1 - 0.0047 16.9 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ATP_bind_1 PF03029.17 CDJ93755.1 - 4.2e-87 291.9 0.3 4.8e-87 291.7 0.3 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 CDJ93755.1 - 8.2e-06 25.7 0.0 0.00015 21.7 0.0 2.5 2 1 2 4 4 4 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_18 PF13238.6 CDJ93755.1 - 0.00012 22.7 0.5 0.014 16.0 0.0 2.8 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.6 CDJ93755.1 - 0.00016 22.1 1.1 1.3 9.5 0.1 3.1 2 1 1 3 3 3 2 AAA domain Gtr1_RagA PF04670.12 CDJ93755.1 - 0.0064 15.9 0.1 1.1 8.6 0.1 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_30 PF13604.6 CDJ93755.1 - 0.021 14.5 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 CDJ93755.1 - 0.044 13.3 0.4 0.18 11.3 0.4 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDJ93755.1 - 0.06 13.3 0.1 12 5.8 0.0 2.7 3 0 0 3 3 3 0 RsgA GTPase AAA_33 PF13671.6 CDJ93755.1 - 0.063 13.4 0.0 0.24 11.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CDJ93755.1 - 0.072 13.5 0.0 0.22 11.9 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 CDJ93755.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 CDJ93755.1 - 0.15 11.8 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain CbiA PF01656.23 CDJ93755.1 - 0.16 12.0 0.0 0.2 11.7 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain zf-C3Hc3H PF13891.6 CDJ93756.1 - 5.7e-20 71.5 16.8 3.2e-12 46.6 2.5 2.5 2 0 0 2 2 2 2 Potential DNA-binding domain Clc-like PF07062.12 CDJ93757.1 - 3.4e-75 252.2 21.2 3.5e-51 173.7 5.1 2.1 2 0 0 2 2 2 2 Clc-like Claudin_2 PF13903.6 CDJ93757.1 - 1.5e-06 28.1 18.9 0.00033 20.5 4.5 2.4 2 1 0 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 CDJ93757.1 - 1.6e-05 24.9 29.3 0.00036 20.5 8.3 3.4 3 1 0 3 3 3 2 Tight junction protein, Claudin-like 7TM-7TMR_HD PF07698.11 CDJ93757.1 - 0.011 15.5 9.4 0.011 15.5 9.4 2.7 2 1 0 2 2 2 0 7TM receptor with intracellular HD hydrolase UCH PF00443.29 CDJ93758.1 - 2.3e-59 201.0 2.0 4.8e-59 199.9 2.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ93758.1 - 2.8e-27 96.2 5.4 2.8e-27 96.2 5.4 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase FHA PF00498.26 CDJ93758.1 - 5e-17 62.0 0.0 1.7e-16 60.3 0.0 2.0 2 0 0 2 2 2 1 FHA domain dsrm PF00035.26 CDJ93758.1 - 3.3e-10 40.5 0.2 1.8e-08 35.0 0.1 2.7 2 0 0 2 2 2 1 Double-stranded RNA binding motif Yop-YscD_cpl PF16697.5 CDJ93758.1 - 2.2e-07 31.1 0.0 9.8e-07 29.0 0.0 2.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Dicer_dimer PF03368.14 CDJ93758.1 - 8.1e-05 22.7 0.1 0.00042 20.4 0.0 2.3 3 0 0 3 3 3 1 Dicer dimerisation domain Ndc1_Nup PF09531.10 CDJ93758.1 - 0.32 9.6 4.3 0.49 9.0 4.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Occludin_ELL PF07303.13 CDJ93758.1 - 0.95 10.2 6.3 0.47 11.2 2.2 2.7 2 0 0 2 2 2 0 Occludin homology domain Peptidase_C98 PF15499.6 CDJ93758.1 - 4.5 6.7 15.7 0.5 9.8 7.8 3.1 3 1 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase ECH_2 PF16113.5 CDJ93759.1 - 4.5e-134 447.2 0.0 5.1e-134 447.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CDJ93759.1 - 1.8e-29 102.8 0.2 5.5e-27 94.7 0.0 2.1 1 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Myosin_head PF00063.21 CDJ93760.1 - 5.7e-248 824.6 0.7 7e-248 824.3 0.7 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 CDJ93760.1 - 2e-34 118.9 0.0 4.5e-34 117.8 0.0 1.6 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding AAA_22 PF13401.6 CDJ93760.1 - 0.016 15.5 0.0 0.083 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CDJ93760.1 - 0.039 14.3 0.0 0.22 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain IQ PF00612.27 CDJ93760.1 - 0.9 9.5 6.6 0.23 11.4 1.3 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif ATP-synt_C PF00137.21 CDJ93761.1 - 3e-35 120.4 31.9 5.3e-22 77.9 13.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C SH PF01445.17 CDJ93761.1 - 0.19 11.7 1.0 0.53 10.3 0.2 1.9 2 0 0 2 2 2 0 Viral small hydrophobic protein DUF2970 PF11174.8 CDJ93761.1 - 6.1 6.8 8.9 1 9.3 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Cullin PF00888.22 CDJ93762.1 - 3.1e-193 643.8 16.5 3.8e-193 643.5 16.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CDJ93762.1 - 3.4e-28 97.5 2.2 1.1e-27 95.8 2.2 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF2063 PF09836.9 CDJ93762.1 - 0.063 13.5 0.1 2.1 8.6 0.0 2.9 2 0 0 2 2 2 0 Putative DNA-binding domain Tau95 PF09734.9 CDJ93762.1 - 0.23 12.2 4.7 8.9 7.1 0.0 3.2 3 1 0 3 3 3 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain RVT_1 PF00078.27 CDJ93763.1 - 0.0023 17.5 0.1 0.007 15.9 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_hydro_20 PF00728.22 CDJ93765.1 - 1.4e-66 225.3 0.0 2.1e-66 224.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 CDJ93765.1 - 3.5e-16 60.1 0.3 2.5e-15 57.4 0.1 2.4 2 1 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 CDJ93765.1 - 0.0027 18.5 0.0 0.0043 17.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Mito_carr PF00153.27 CDJ93766.1 - 1.1e-49 166.3 1.0 3.1e-18 65.5 0.0 3.7 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.16 CDJ93766.1 - 3.7e-24 85.3 27.1 7.3e-24 84.3 27.1 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Serine_protease PF18405.1 CDJ93766.1 - 0.034 13.3 0.0 1.5 7.9 0.0 2.8 3 0 0 3 3 3 0 Gammaproteobacterial serine protease SLATT_3 PF18184.1 CDJ93766.1 - 0.55 10.4 1.9 1.4 9.0 0.0 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 LIM PF00412.22 CDJ93771.1 - 1.6e-32 111.5 33.3 4.2e-14 52.5 7.2 3.4 3 0 0 3 3 3 3 LIM domain L27_1 PF09058.10 CDJ93771.1 - 0.029 14.3 0.8 0.1 12.6 0.8 1.9 1 0 0 1 1 1 0 L27_1 DUF2685 PF10886.8 CDJ93771.1 - 0.73 10.1 0.1 0.73 10.1 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2685) DUF812 PF05667.11 CDJ93771.1 - 0.99 8.2 13.9 1.4 7.7 13.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FUSC PF04632.12 CDJ93771.1 - 9.7 4.6 4.9 13 4.2 4.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Serpin PF00079.20 CDJ93772.1 - 8.1e-78 262.3 1.9 9.6e-78 262.1 1.9 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Iso_dh PF00180.20 CDJ93775.1 - 1.3e-92 310.6 0.0 1.8e-92 310.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Peptidase_S9 PF00326.21 CDJ93776.1 - 2.7e-15 56.4 0.2 2.9e-15 56.3 0.2 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 CDJ93776.1 - 0.005 16.4 0.0 0.0054 16.3 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 CDJ93777.1 - 2.5e-20 72.9 0.0 2.8e-20 72.7 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2920 PF11144.8 CDJ93777.1 - 0.00022 20.6 0.0 0.00024 20.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Abhydrolase_6 PF12697.7 CDJ93777.1 - 0.00052 20.7 0.1 0.00053 20.7 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDJ93777.1 - 0.0073 15.6 0.0 0.0076 15.5 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S28 PF05577.12 CDJ93777.1 - 0.015 14.1 0.0 0.017 13.9 0.0 1.0 1 0 0 1 1 1 0 Serine carboxypeptidase S28 AXE1 PF05448.12 CDJ93777.1 - 0.02 13.5 0.0 0.022 13.4 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF1100 PF06500.11 CDJ93777.1 - 0.03 13.1 0.0 0.033 13.0 0.0 1.0 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) TAL_effector PF03377.13 CDJ93777.1 - 0.034 14.5 0.1 0.061 13.6 0.1 1.4 1 0 0 1 1 1 0 TAL effector repeat Esterase PF00756.20 CDJ93777.1 - 0.054 13.1 0.0 0.066 12.9 0.0 1.1 1 0 0 1 1 1 0 Putative esterase Chlorophyllase2 PF12740.7 CDJ93777.1 - 0.087 11.7 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme MFMR PF07777.11 CDJ93777.1 - 0.16 12.5 0.0 0.18 12.3 0.0 1.1 1 0 0 1 1 1 0 G-box binding protein MFMR Ion_trans PF00520.31 CDJ93778.1 - 8.8e-35 120.1 6.8 1.2e-34 119.6 6.8 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 CDJ93778.1 - 7.5e-15 54.8 0.0 1.9e-14 53.5 0.0 1.7 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 CDJ93778.1 - 4.2e-10 39.4 3.0 4.2e-10 39.4 3.0 2.3 3 0 0 3 3 3 1 Ion channel Tropomyosin_1 PF12718.7 CDJ93778.1 - 0.026 14.7 0.1 0.043 14.0 0.1 1.2 1 0 0 1 1 1 0 Tropomyosin like IRK PF01007.20 CDJ93778.1 - 0.42 10.4 5.2 0.51 10.1 0.5 2.4 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain MPC PF03650.13 CDJ93779.1 - 5.7e-43 145.6 0.1 6.3e-43 145.4 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers KH_1 PF00013.29 CDJ93780.1 - 2.1e-23 81.9 2.8 1.9e-11 43.6 0.5 2.2 2 0 0 2 2 2 2 KH domain MOEP19 PF16005.5 CDJ93780.1 - 4.6e-06 26.5 0.1 0.047 13.7 0.0 2.2 2 0 0 2 2 2 2 KH-like RNA-binding domain KH_2 PF07650.17 CDJ93780.1 - 8.5e-05 22.3 2.2 0.12 12.2 0.1 2.4 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 CDJ93780.1 - 0.01 15.7 0.7 2.1 8.3 0.1 2.5 2 0 0 2 2 2 0 KH domain KH_5 PF13184.6 CDJ93780.1 - 0.02 15.0 1.6 7.4 6.7 0.6 3.0 2 1 0 2 2 2 0 NusA-like KH domain Complex1_30kDa PF00329.19 CDJ93781.1 - 2.1e-42 144.6 0.0 3.2e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit BTB PF00651.31 CDJ93782.1 - 5.4e-31 107.1 0.3 1.1e-30 106.2 0.1 1.6 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 CDJ93782.1 - 8.4e-31 106.1 1.1 1.9e-30 105.0 0.4 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 CDJ93782.1 - 8.5e-27 92.5 0.1 2.6e-14 52.5 0.0 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 CDJ93782.1 - 8.9e-11 41.7 0.1 0.00037 20.7 0.0 2.5 1 1 1 2 2 2 2 Kelch motif Kelch_2 PF07646.15 CDJ93782.1 - 6e-08 32.4 0.1 0.0019 18.1 0.0 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 CDJ93782.1 - 1.4e-07 31.4 0.0 0.021 14.8 0.0 2.5 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ93782.1 - 4.6e-06 26.8 0.0 0.16 12.3 0.0 2.4 2 0 0 2 2 2 2 Galactose oxidase, central domain DUF3342 PF11822.8 CDJ93782.1 - 0.0017 18.5 0.2 0.015 15.5 0.0 2.5 2 1 1 3 3 3 1 Domain of unknown function (DUF3342) Kelch_5 PF13854.6 CDJ93782.1 - 0.06 13.3 0.1 1.6 8.8 0.1 2.5 2 0 0 2 2 2 0 Kelch motif SNARE PF05739.19 CDJ93783.1 - 3.5e-15 55.7 3.1 9.1e-15 54.4 3.1 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 CDJ93783.1 - 2.1e-08 34.1 8.9 3.7e-08 33.3 8.9 1.4 1 0 0 1 1 1 1 Syntaxin DUF3675 PF12428.8 CDJ93783.1 - 0.069 13.7 0.4 0.069 13.7 0.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3675) MMPL PF03176.15 CDJ93783.1 - 0.22 10.4 0.9 0.26 10.2 0.1 1.5 2 0 0 2 2 2 0 MMPL family Rx_N PF18052.1 CDJ93783.1 - 0.33 11.3 2.9 11 6.3 0.1 2.6 2 1 0 2 2 2 0 Rx N-terminal domain FlaF PF07309.11 CDJ93783.1 - 1.1 9.3 5.3 0.37 10.8 0.3 2.4 3 0 0 3 3 3 0 Flagellar protein FlaF Med2 PF11214.8 CDJ93783.1 - 7.5 6.8 12.2 0.79 9.9 3.2 3.1 3 1 1 4 4 4 0 Mediator complex subunit 2 HATPase_c_3 PF13589.6 CDJ93784.1 - 1.1e-21 77.0 0.0 1.8e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDJ93784.1 - 0.00056 20.4 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase G0-G1_switch_2 PF15103.6 CDJ93785.1 - 0.022 15.2 0.1 0.022 15.2 0.1 3.1 2 1 0 2 2 2 0 G0/G1 switch protein 2 gag-asp_proteas PF13975.6 CDJ93786.1 - 9e-07 29.4 0.4 2.2e-06 28.1 0.4 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ93786.1 - 0.017 15.8 0.4 0.04 14.6 0.4 1.7 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 CDJ93786.1 - 0.11 12.8 0.1 0.83 10.0 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease MLVIN_C PF18697.1 CDJ93787.1 - 0.067 13.3 0.2 0.55 10.4 0.0 2.6 2 1 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain RVT_1 PF00078.27 CDJ93788.1 - 1.8e-33 115.9 0.0 2.3e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RabGAP-TBC PF00566.18 CDJ93790.1 - 7e-09 35.7 1.3 1e-08 35.1 1.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain HAGH_C PF16123.5 CDJ93791.1 - 0.0016 18.9 0.3 0.0027 18.2 0.3 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus DDE_Tnp_1_7 PF13843.6 CDJ93791.1 - 0.004 16.5 1.8 1.5 8.0 0.2 2.7 1 1 2 3 3 3 2 Transposase IS4 Spore_III_AB PF09548.10 CDJ93791.1 - 0.0045 17.1 0.7 0.006 16.7 0.2 1.5 2 0 0 2 2 2 1 Stage III sporulation protein AB (spore_III_AB) Apo-CIII PF05778.12 CDJ93791.1 - 0.064 12.9 0.5 0.11 12.1 0.5 1.4 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Piwi PF02171.17 CDJ93792.1 - 0.07 12.4 0.1 0.099 11.9 0.1 1.2 1 0 0 1 1 1 0 Piwi domain RVT_1 PF00078.27 CDJ93793.1 - 9.7e-13 48.1 0.0 1.4e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) His_Phos_1 PF00300.22 CDJ93796.1 - 1e-14 54.7 0.0 1.3e-13 51.1 0.0 2.2 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) PHBC_N PF12551.8 CDJ93796.1 - 0.01 15.6 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase N terminal ABC_membrane PF00664.23 CDJ93797.1 - 3.4e-56 190.9 6.0 5e-56 190.4 6.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ93797.1 - 1.5e-30 106.5 0.7 2.5e-15 57.2 0.0 3.4 3 1 0 3 3 3 2 ABC transporter SMC_N PF02463.19 CDJ93797.1 - 1.2e-07 31.4 1.5 1.5e-05 24.6 0.0 2.5 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDJ93797.1 - 0.0011 19.4 0.1 0.0083 16.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain ABC_ATPase PF09818.9 CDJ93797.1 - 0.0011 17.8 1.5 0.002 17.0 0.0 2.0 2 0 0 2 2 2 1 Predicted ATPase of the ABC class Rad17 PF03215.15 CDJ93797.1 - 0.0031 17.5 0.0 0.0082 16.1 0.0 1.7 2 0 0 2 2 1 1 Rad17 P-loop domain IstB_IS21 PF01695.17 CDJ93797.1 - 0.0043 16.8 0.1 0.07 12.9 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 CDJ93797.1 - 0.0046 16.3 0.1 0.028 13.7 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 CDJ93797.1 - 0.005 17.1 0.0 0.1 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CDJ93797.1 - 0.0052 16.7 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 CDJ93797.1 - 0.0052 16.6 0.0 0.77 9.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CDJ93797.1 - 0.0064 16.3 0.1 0.038 13.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CDJ93797.1 - 0.0066 16.5 1.6 0.15 12.1 0.0 3.4 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA PF00004.29 CDJ93797.1 - 0.012 16.0 0.0 1.9 8.9 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CDJ93797.1 - 0.021 14.6 1.2 0.37 10.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 CDJ93797.1 - 0.021 15.1 1.0 0.28 11.5 1.0 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 CDJ93797.1 - 0.041 13.6 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 CDJ93797.1 - 0.36 11.3 2.3 5.7 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain LapA_dom PF06305.11 CDJ93797.1 - 6 6.8 6.2 2.1 8.2 1.4 2.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain ABC_tran PF00005.27 CDJ93799.1 - 6.1e-48 162.8 0.0 2.4e-23 83.2 0.0 2.8 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 CDJ93799.1 - 5.1e-20 72.5 0.0 0.00013 21.9 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 CDJ93799.1 - 1.1e-19 70.3 4.0 1.4e-18 66.7 4.0 2.6 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 CDJ93799.1 - 8.5e-10 38.4 0.3 0.071 12.5 0.0 4.7 4 1 1 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CDJ93799.1 - 9.4e-09 34.9 0.0 0.0069 16.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 CDJ93799.1 - 9.2e-08 32.2 2.9 0.013 15.2 0.0 4.0 3 1 0 4 4 4 2 AAA ATPase domain AAA_23 PF13476.6 CDJ93799.1 - 3.3e-07 31.0 4.2 0.0055 17.2 0.0 3.3 4 0 0 4 4 4 2 AAA domain MMR_HSR1 PF01926.23 CDJ93799.1 - 8.7e-06 25.8 0.1 0.083 13.0 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.6 CDJ93799.1 - 1.3e-05 25.4 0.4 0.28 11.3 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.6 CDJ93799.1 - 2e-05 25.0 0.0 0.19 12.1 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 CDJ93799.1 - 9.5e-05 23.0 0.0 0.4 11.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 CDJ93799.1 - 0.00022 21.2 0.0 0.084 12.8 0.0 2.6 2 1 0 2 2 2 1 RsgA GTPase NB-ARC PF00931.22 CDJ93799.1 - 0.00058 19.1 0.0 0.27 10.4 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_30 PF13604.6 CDJ93799.1 - 0.0007 19.4 0.1 0.91 9.2 0.0 3.4 3 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 CDJ93799.1 - 0.00076 19.8 0.0 0.13 12.6 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 CDJ93799.1 - 0.00083 19.6 0.0 1 9.6 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 CDJ93799.1 - 0.00095 19.6 0.0 1 9.8 0.0 3.2 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CDJ93799.1 - 0.001 19.3 0.0 0.46 10.7 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_27 PF13514.6 CDJ93799.1 - 0.0016 18.1 0.1 2.7 7.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 CDJ93799.1 - 0.0019 18.2 0.0 3.1 7.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) DUF87 PF01935.17 CDJ93799.1 - 0.0026 17.9 0.3 2.4 8.2 0.0 2.8 3 0 0 3 3 2 1 Helicase HerA, central domain MukB PF04310.12 CDJ93799.1 - 0.003 17.4 2.6 1.3 8.8 0.0 3.2 3 1 1 4 4 4 2 MukB N-terminal NACHT PF05729.12 CDJ93799.1 - 0.0032 17.4 0.8 1.1 9.2 0.0 3.0 2 1 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 CDJ93799.1 - 0.0033 17.5 0.0 5.6 7.0 0.0 3.3 4 0 0 4 4 2 0 AAA domain AAA_25 PF13481.6 CDJ93799.1 - 0.0037 16.9 0.0 0.045 13.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 CDJ93799.1 - 0.0053 16.8 0.0 2.8 8.0 0.0 2.8 2 1 0 2 2 2 1 Dynamin family Arf PF00025.21 CDJ93799.1 - 0.01 15.3 0.0 4.7 6.6 0.0 2.7 2 0 0 2 2 2 0 ADP-ribosylation factor family Roc PF08477.13 CDJ93799.1 - 0.011 16.0 0.0 2.2 8.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 CDJ93799.1 - 0.013 15.2 0.0 0.84 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CDJ93799.1 - 0.017 14.7 0.0 5.1 6.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 CDJ93799.1 - 0.017 15.0 0.9 0.88 9.4 0.0 3.1 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 CDJ93799.1 - 0.021 15.3 0.0 9.2 6.7 0.0 3.0 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 CDJ93799.1 - 0.031 13.8 0.1 2.4 7.7 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 CDJ93799.1 - 0.058 12.4 1.8 2.2 7.2 0.0 2.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF815 PF05673.13 CDJ93799.1 - 0.067 12.3 0.4 13 4.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 CDJ93799.1 - 0.092 12.7 0.0 4.2 7.3 0.0 2.5 2 0 0 2 2 2 0 NTPase SbcCD_C PF13558.6 CDJ93799.1 - 0.13 12.5 0.0 2.8 8.2 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Neur_chan_LBD PF02931.23 CDJ93801.1 - 2.4e-18 66.4 0.2 2.8e-18 66.2 0.2 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Pkinase PF00069.25 CDJ93802.1 - 1.7e-60 204.6 0.0 2.1e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ93802.1 - 1.3e-40 139.4 0.0 1.6e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ93802.1 - 6.6e-10 38.8 0.0 9.7e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CDJ93802.1 - 4.4e-05 22.6 0.3 8.2e-05 21.7 0.3 1.6 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CDJ93802.1 - 0.00012 21.8 0.0 0.00026 20.7 0.0 1.4 1 1 0 1 1 1 1 RIO1 family FTA2 PF13095.6 CDJ93802.1 - 0.00083 19.0 0.6 0.43 10.2 0.1 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CDJ93802.1 - 0.0085 14.9 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDJ93802.1 - 0.016 15.1 0.0 0.22 11.4 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1759 PF03564.15 CDJ93803.1 - 7.7e-23 81.1 0.2 1.6e-22 80.1 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) ArsR PF09824.9 CDJ93803.1 - 0.0038 16.8 0.2 0.0076 15.9 0.0 1.5 2 0 0 2 2 2 1 ArsR transcriptional regulator T6PP_N PF18572.1 CDJ93804.1 - 0.72 9.7 12.7 0.29 11.0 1.8 3.3 2 1 0 3 3 3 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain RRN3 PF05327.11 CDJ93804.1 - 0.89 8.0 8.5 1.2 7.6 8.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CWC25 PF12542.8 CDJ93804.1 - 3.4 8.6 6.8 7.2 7.6 6.4 1.8 1 1 0 1 1 1 0 Pre-mRNA splicing factor XhlA PF10779.9 CDJ93804.1 - 3.9 7.8 12.5 13 6.1 2.0 3.5 2 1 0 3 3 3 0 Haemolysin XhlA Peptidase_C1 PF00112.23 CDJ93805.1 - 8.2e-63 212.4 3.7 9.9e-63 212.1 3.7 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ93805.1 - 0.59 8.8 5.0 0.16 10.7 1.1 1.8 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ93806.1 - 1.3e-60 205.2 2.9 1.5e-60 205.0 2.9 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ93806.1 - 0.12 11.1 3.6 0.08 11.7 0.5 1.9 2 0 0 2 2 2 0 Peptidase C1-like family rve_3 PF13683.6 CDJ93807.1 - 0.049 13.4 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain ArgoN PF16486.5 CDJ93808.1 - 5.2e-09 36.8 0.0 8.8e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 CDJ93808.1 - 1.6e-05 24.4 0.0 2.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Argonaute linker 1 domain DUF1759 PF03564.15 CDJ93809.1 - 1.7e-06 28.0 2.0 1.9e-05 24.7 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1759) TPR_MalT PF17874.1 CDJ93809.1 - 0.0031 17.0 0.1 0.004 16.6 0.1 1.1 1 0 0 1 1 1 1 MalT-like TPR region Laminin_II PF06009.12 CDJ93809.1 - 0.027 14.5 1.2 0.043 13.8 1.2 1.4 1 0 0 1 1 1 0 Laminin Domain II Phage_GPO PF05929.11 CDJ93809.1 - 0.029 14.0 0.9 0.037 13.6 0.9 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2119 PF09892.9 CDJ93809.1 - 0.095 12.1 0.2 0.15 11.5 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) Endotoxin_C2 PF18449.1 CDJ93809.1 - 0.64 10.4 5.5 1.6 9.1 0.4 3.2 2 1 0 3 3 3 0 Delta endotoxin Peptidase_C1 PF00112.23 CDJ93810.1 - 2.9e-61 207.3 1.9 2.9e-61 207.3 1.9 1.7 2 0 0 2 2 2 1 Papain family cysteine protease AAA_12 PF13087.6 CDJ93810.1 - 0.00038 20.1 0.0 0.00057 19.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Peptidase_C1_2 PF03051.15 CDJ93810.1 - 0.047 12.5 1.9 0.093 11.5 0.5 1.8 2 0 0 2 2 2 0 Peptidase C1-like family RVT_1 PF00078.27 CDJ93811.1 - 8.3e-06 25.5 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C1 PF00112.23 CDJ93812.1 - 3.8e-64 216.8 5.6 4.5e-64 216.5 5.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ93812.1 - 0.012 14.4 2.9 0.016 14.0 0.3 1.9 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ93813.1 - 6.7e-61 206.2 10.6 8e-61 205.9 10.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ93813.1 - 0.031 13.1 1.6 0.046 12.5 0.4 1.7 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 CDJ93814.1 - 4e-61 206.9 10.4 5e-61 206.6 10.4 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Conotoxin_I2 PF17557.2 CDJ93814.1 - 0.1 12.8 4.9 3.1 8.0 0.1 2.7 2 0 0 2 2 2 0 I2-superfamily conotoxins Peptidase_C1_2 PF03051.15 CDJ93814.1 - 0.29 9.9 3.9 0.93 8.2 1.0 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Gal-bind_lectin PF00337.22 CDJ93815.1 - 5.4e-67 223.4 0.2 8.5e-36 122.4 0.0 2.0 2 0 0 2 2 2 2 Galactoside-binding lectin Alginate_lyase2 PF08787.11 CDJ93815.1 - 0.062 13.1 0.1 0.14 12.0 0.0 1.7 1 1 1 2 2 2 0 Alginate lyase DUF273 PF03314.14 CDJ93817.1 - 2.4e-12 46.9 0.1 3.4e-12 46.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF273 DUF4348 PF14254.6 CDJ93818.1 - 0.095 12.1 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4348) BTB PF00651.31 CDJ93819.1 - 0.0045 17.2 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain TFIIS_M PF07500.14 CDJ93824.1 - 8.5e-10 39.1 0.2 8.5e-10 39.1 0.2 2.5 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 CDJ93824.1 - 1.4e-06 28.3 0.0 3.2e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 SPOC domain Fer4_22 PF17179.4 CDJ93824.1 - 3.8 8.4 8.8 0.51 11.2 2.8 2.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain Aa_trans PF01490.18 CDJ93825.1 - 1e-54 185.9 30.8 1.6e-54 185.2 30.8 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein AC_N PF16214.5 CDJ93825.1 - 1 8.4 3.4 2.2 7.3 3.4 1.4 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Brr6_like_C_C PF10104.9 CDJ93825.1 - 4.4 7.1 6.4 2.1 8.1 0.0 3.3 3 0 0 3 3 3 0 Di-sulfide bridge nucleocytoplasmic transport domain CSTF2_hinge PF14327.6 CDJ93827.1 - 4.5e-29 100.7 1.0 4.5e-29 100.7 1.0 2.0 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 CDJ93827.1 - 2.6e-23 81.6 0.0 4.2e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 CDJ93827.1 - 1.8e-15 56.2 2.9 8.7e-15 54.0 2.0 2.5 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_occluded PF16842.5 CDJ93827.1 - 8.8e-05 22.3 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 CDJ93827.1 - 0.045 13.4 0.0 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1667 PF07892.11 CDJ93827.1 - 0.072 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) RRM_Rrp7 PF17799.1 CDJ93827.1 - 0.089 12.6 0.0 8.9 6.1 0.0 2.2 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain ABC_trans_aux PF03886.13 CDJ93827.1 - 0.2 11.2 4.1 0.25 10.9 0.4 2.3 2 0 0 2 2 2 0 ABC-type transport auxiliary lipoprotein component SPATA3 PF15662.5 CDJ93827.1 - 6.3 7.4 7.6 0.6 10.7 2.8 1.6 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family AAA_lid_3 PF17862.1 CDJ93828.1 - 2.7e-12 46.3 0.0 4.4e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 CDJ93828.1 - 3.7e-05 24.2 0.1 0.00021 21.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Recep_L_domain PF01030.24 CDJ93829.1 - 1.3e-10 41.4 0.6 3e-05 24.1 0.1 2.3 2 0 0 2 2 2 2 Receptor L domain TAP35_44 PF07265.11 CDJ93829.1 - 0.16 12.0 0.4 2.3 8.3 0.0 2.1 1 1 1 2 2 2 0 Tapetum specific protein TAP35/TAP44 EF-hand_1 PF00036.32 CDJ93830.1 - 8.7e-32 106.3 2.6 0.0001 21.6 0.0 6.2 6 0 0 6 6 6 6 EF hand EF-hand_7 PF13499.6 CDJ93830.1 - 1.7e-31 108.4 20.1 1.4e-08 35.1 0.4 4.5 1 1 5 6 6 6 6 EF-hand domain pair EF-hand_6 PF13405.6 CDJ93830.1 - 4.4e-28 94.8 4.8 0.00088 19.0 0.0 6.3 6 0 0 6 6 6 6 EF-hand domain EF-hand_5 PF13202.6 CDJ93830.1 - 4.9e-26 89.0 5.3 0.00018 20.8 0.0 6.6 6 0 0 6 6 6 5 EF hand EF-hand_8 PF13833.6 CDJ93830.1 - 1.9e-16 59.6 9.8 0.024 14.5 0.1 6.1 3 3 3 6 6 6 6 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ93830.1 - 3.6e-10 40.1 2.2 0.0096 16.2 0.7 4.0 1 1 3 4 4 4 4 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 CDJ93830.1 - 1.1e-05 25.2 1.5 7 6.6 0.0 4.8 5 1 0 5 5 5 2 EF hand EF-hand_4 PF12763.7 CDJ93830.1 - 4.5e-05 23.3 4.5 0.22 11.5 0.1 4.3 2 1 3 5 5 5 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 CDJ93830.1 - 0.0097 16.1 12.2 0.27 11.4 2.2 4.2 3 2 1 4 4 4 1 Dockerin type I domain Cnl2_NKP2 PF09447.10 CDJ93830.1 - 0.011 15.8 0.1 0.053 13.7 0.0 2.1 2 0 0 2 2 2 0 Cnl2/NKP2 family protein FG-GAP PF01839.23 CDJ93830.1 - 0.018 15.2 6.4 0.12 12.5 0.9 2.9 3 0 0 3 3 3 0 FG-GAP repeat PMBR PF09373.10 CDJ93830.1 - 0.021 15.0 1.7 7.1 7.0 0.1 4.6 4 1 1 5 5 5 0 Pseudomurein-binding repeat VCBS PF13517.6 CDJ93830.1 - 0.078 13.6 4.1 2.8 8.6 0.2 3.2 3 1 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella LnmK_N_HDF PF18238.1 CDJ93830.1 - 0.16 11.7 0.1 1.8 8.3 0.1 2.3 2 1 0 2 2 2 0 LnmK N-terminal Hot Dog Fold domain TTR-52 PF01060.23 CDJ93831.1 - 2.1e-16 60.4 0.0 3.1e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Transthyretin-like family EF-hand_1 PF00036.32 CDJ93832.1 - 5.4e-35 116.3 21.9 0.00023 20.5 0.2 11.3 11 0 0 11 11 11 8 EF hand EF-hand_7 PF13499.6 CDJ93832.1 - 1.2e-30 105.8 18.6 4.9e-05 23.7 0.1 8.1 5 3 3 9 9 9 8 EF-hand domain pair EF-hand_5 PF13202.6 CDJ93832.1 - 3.5e-29 99.0 25.4 0.0036 16.7 0.1 10.3 10 0 0 10 10 10 9 EF hand EF-hand_6 PF13405.6 CDJ93832.1 - 5.1e-25 85.2 24.5 0.01 15.7 0.0 11.2 11 0 0 11 11 11 8 EF-hand domain EF-hand_8 PF13833.6 CDJ93832.1 - 6.7e-17 61.1 22.9 0.0018 18.1 0.1 8.9 7 2 2 9 9 9 6 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ93832.1 - 1.2e-15 57.8 8.3 2.1e-06 28.0 0.1 6.2 2 2 4 6 6 6 5 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 CDJ93832.1 - 3.2e-08 33.3 0.7 0.29 11.0 0.0 6.3 6 0 0 6 6 6 1 EF hand Dockerin_1 PF00404.18 CDJ93832.1 - 0.059 13.6 11.7 15 5.9 0.0 6.1 6 0 0 6 6 6 0 Dockerin type I domain Mucin PF01456.17 CDJ93832.1 - 0.68 9.9 38.3 0.1 12.6 29.2 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein RVT_1 PF00078.27 CDJ93833.1 - 1.6e-37 129.2 0.0 3.2e-37 128.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3629 PF12302.8 CDJ93833.1 - 0.022 14.2 0.4 0.04 13.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) GLEYA PF10528.9 CDJ93834.1 - 0.015 15.7 0.0 0.027 14.9 0.0 1.4 1 0 0 1 1 1 0 GLEYA domain RVT_1 PF00078.27 CDJ93835.1 - 1.9e-44 151.9 0.0 2.8e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CDJ93837.1 - 3.7e-08 33.1 0.0 5.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SURF6 PF04935.12 CDJ93838.1 - 3.1e-29 102.2 91.6 3.6e-28 98.7 79.5 2.6 1 1 1 2 2 2 1 Surfeit locus protein 6 Imm74 PF15603.6 CDJ93838.1 - 0.059 13.6 0.4 0.44 10.8 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 74 Apolipoprotein PF01442.18 CDJ93839.1 - 8.8e-06 25.7 1.9 1.6e-05 24.9 1.9 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 CDJ93839.1 - 0.0056 16.7 3.9 0.22 11.6 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) DUF4456 PF14644.6 CDJ93839.1 - 0.0062 16.3 3.6 0.012 15.3 3.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4456) Seryl_tRNA_N PF02403.22 CDJ93839.1 - 0.013 15.8 0.9 0.013 15.8 0.9 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF356 PF04009.12 CDJ93839.1 - 0.015 15.5 0.5 0.039 14.2 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF356) Prominin PF05478.11 CDJ93839.1 - 0.093 10.7 2.4 0.13 10.2 2.4 1.2 1 0 0 1 1 1 0 Prominin Baculo_PEP_C PF04513.12 CDJ93839.1 - 0.096 12.7 1.0 0.53 10.3 1.0 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tfb5 PF06331.12 CDJ93839.1 - 0.11 12.5 2.9 0.15 12.0 0.3 2.5 2 1 1 3 3 3 0 Transcription factor TFIIH complex subunit Tfb5 SPX PF03105.19 CDJ93839.1 - 0.3 11.0 12.2 4.4 7.1 12.2 1.9 1 1 0 1 1 1 0 SPX domain Phasin PF05597.11 CDJ93839.1 - 2.2 8.3 8.7 0.071 13.1 2.4 1.7 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) BRCT_2 PF16589.5 CDJ93840.1 - 4.5e-11 43.0 0.0 5.7e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CDJ93840.1 - 0.00072 19.9 0.0 0.0014 19.0 0.0 1.4 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 CDJ93840.1 - 0.0033 17.3 0.0 0.0045 16.8 0.0 1.2 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 CDJ93841.1 - 4.9e-06 26.8 0.0 8.9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CDJ93841.1 - 0.00046 20.1 0.0 0.00095 19.1 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain RTT107_BRCT_5 PF16770.5 CDJ93841.1 - 0.013 15.3 0.0 0.11 12.5 0.0 2.3 2 1 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 CDJ93841.1 - 0.029 14.8 0.0 0.056 13.9 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain FoP_duplication PF13865.6 CDJ93842.1 - 0.11 13.1 19.6 0.075 13.6 14.5 2.4 2 1 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 SET PF00856.28 CDJ93843.1 - 8.9e-19 68.5 0.0 1.5e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 SET domain RasGAP PF00616.19 CDJ93843.1 - 0.031 14.0 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase Rubis-subs-bind PF09273.11 CDJ93843.1 - 0.052 14.2 0.3 0.12 13.1 0.3 1.5 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding fn3 PF00041.21 CDJ93844.1 - 0.0039 17.5 0.1 0.0082 16.5 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain CSRNP_N PF16019.5 CDJ93845.1 - 8.7e-36 123.9 23.5 4.5e-27 95.4 8.8 3.2 4 0 0 4 4 4 2 Cysteine/serine-rich nuclear protein N-terminus RVT_1 PF00078.27 CDJ93847.1 - 2.9e-11 43.3 0.0 7.1e-11 42.0 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) ATP-synt_B PF00430.18 CDJ93847.1 - 0.049 13.7 1.3 0.11 12.6 1.3 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Sortase PF04203.13 CDJ93848.1 - 0.046 13.5 0.1 0.056 13.3 0.1 1.1 1 0 0 1 1 1 0 Sortase domain ShK PF01549.24 CDJ93850.1 - 8e-05 23.1 5.9 0.00011 22.6 5.9 1.2 1 0 0 1 1 1 1 ShK domain-like Cnd3 PF12719.7 CDJ93850.1 - 0.14 11.3 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain Pannexin_like PF12534.8 CDJ93850.1 - 0.19 10.8 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DNA_pol_phi PF04931.13 CDJ93850.1 - 2.3 6.2 5.1 2.4 6.1 5.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi ABC_tran PF00005.27 CDJ93851.1 - 1.5e-55 187.5 0.0 1.2e-29 103.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CDJ93851.1 - 1e-53 182.7 50.2 6.7e-33 114.2 23.3 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 CDJ93851.1 - 3.4e-21 76.3 1.2 1.3e-07 31.7 0.0 4.5 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CDJ93851.1 - 0.00018 22.1 1.4 0.05 14.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC2_membrane PF01061.24 CDJ93851.1 - 0.00021 20.8 66.0 0.00084 18.8 20.4 4.8 5 0 0 5 5 5 3 ABC-2 type transporter RsgA_GTPase PF03193.16 CDJ93851.1 - 0.00094 19.1 0.2 0.15 12.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 CDJ93851.1 - 0.0015 18.1 0.8 2.9 7.2 0.0 3.3 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CDJ93851.1 - 0.008 15.9 2.5 0.12 12.1 0.3 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CDJ93851.1 - 0.014 15.5 0.3 3.2 7.8 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 CDJ93851.1 - 0.029 14.6 0.0 1.3 9.3 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ARPC4 PF05856.12 CDJ93852.1 - 2.3e-80 268.1 4.8 2.6e-80 267.9 4.8 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Sm_like PF16243.5 CDJ93852.1 - 0.068 13.3 0.1 0.13 12.4 0.0 1.6 2 0 0 2 2 2 0 Sm_like domain DUF2012 PF09430.10 CDJ93853.1 - 5.9e-32 110.4 0.0 8.9e-32 109.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 CDJ93853.1 - 0.017 15.4 0.1 0.031 14.5 0.1 1.6 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Arf PF00025.21 CDJ93854.1 - 3.2e-48 163.5 0.0 3.6e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CDJ93854.1 - 9.8e-14 51.3 0.0 1.2e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CDJ93854.1 - 2.9e-13 49.7 0.0 3.4e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 CDJ93854.1 - 9.4e-13 48.4 0.0 1.4e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CDJ93854.1 - 6.2e-10 38.8 0.3 2.4e-06 27.0 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 CDJ93854.1 - 2.9e-07 30.5 0.0 4.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDJ93854.1 - 3.1e-06 26.7 0.0 3.7e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CDJ93854.1 - 5.9e-06 26.0 0.1 0.00076 19.1 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CDJ93854.1 - 0.0037 17.5 0.1 0.02 15.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.18 CDJ93854.1 - 0.015 14.9 0.6 0.05 13.1 0.6 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_18 PF13238.6 CDJ93854.1 - 0.016 15.7 0.0 0.023 15.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Homeodomain PF00046.29 CDJ93855.1 - 5.2e-17 61.4 2.3 8.3e-17 60.8 2.3 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ93855.1 - 0.0097 15.8 0.9 0.0097 15.8 0.9 2.9 3 0 0 3 3 3 1 Homeobox KN domain UCH PF00443.29 CDJ93856.1 - 1.5e-52 178.7 0.0 2e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ93856.1 - 1e-13 51.6 1.9 7e-07 29.1 1.0 2.6 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase EF-hand_6 PF13405.6 CDJ93856.1 - 6e-07 28.9 0.2 0.0022 17.8 0.0 3.8 3 0 0 3 3 3 2 EF-hand domain DUSP PF06337.12 CDJ93856.1 - 8.3e-07 29.6 0.1 2.9e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DUSP domain EF-hand_1 PF00036.32 CDJ93856.1 - 3.1e-06 26.3 4.9 0.0014 18.0 0.1 4.7 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.6 CDJ93856.1 - 0.00049 20.5 2.4 0.0039 17.6 0.3 3.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 CDJ93856.1 - 0.015 14.8 3.7 0.021 14.3 0.4 2.9 3 0 0 3 3 3 0 EF hand UN_NPL4 PF11543.8 CDJ93856.1 - 0.027 15.0 0.0 32 5.1 0.0 3.3 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 Peptidase_C98 PF15499.6 CDJ93856.1 - 0.035 13.6 1.2 2.5 7.5 0.0 2.8 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase EF-hand_8 PF13833.6 CDJ93856.1 - 0.048 13.5 4.0 2.4 8.1 0.1 3.6 3 0 0 3 3 3 0 EF-hand domain pair DUF2053 PF09767.9 CDJ93857.1 - 9.3e-58 194.9 5.0 9.3e-58 194.9 5.0 1.5 2 0 0 2 2 2 1 Predicted membrane protein (DUF2053) LIN37 PF15306.6 CDJ93858.1 - 1e-05 25.8 0.0 1.9e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 LIN37 AP_endonuc_2 PF01261.24 CDJ93859.1 - 3.2e-27 95.3 0.0 4e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Glyco_transf_49 PF13896.6 CDJ93860.1 - 8.4e-21 74.7 2.8 1e-20 74.4 2.8 1.0 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Nic96 PF04097.14 CDJ93861.1 - 7.9e-103 345.0 0.0 9.6e-103 344.7 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 TPR_7 PF13176.6 CDJ93862.1 - 0.0045 16.9 0.1 0.018 15.0 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat SNAP PF14938.6 CDJ93862.1 - 0.0055 16.2 0.0 0.0078 15.7 0.0 1.3 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_8 PF13181.6 CDJ93862.1 - 0.019 15.2 0.1 0.057 13.7 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat PGBA_N PF15436.6 CDJ93862.1 - 0.057 13.0 0.0 0.058 13.0 0.0 1.1 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA N-terminal DUF1774 PF08611.10 CDJ93864.1 - 0.051 13.9 1.8 0.078 13.3 0.1 1.9 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1774) Gram_pos_anchor PF00746.21 CDJ93864.1 - 1 9.4 0.1 1 9.4 0.1 2.7 3 0 0 3 3 3 0 LPXTG cell wall anchor motif Orf78 PF06024.12 CDJ93864.1 - 2.7 8.4 5.7 10 6.5 0.5 2.2 2 0 0 2 2 2 0 Orf78 (ac78) zf-H2C2_5 PF13909.6 CDJ93865.1 - 3.7e-05 23.4 4.8 0.0061 16.3 0.8 2.4 2 0 0 2 2 2 2 C2H2-type zinc-finger domain Peptidase_C78 PF07910.13 CDJ93867.1 - 2.1e-47 161.4 0.0 2.9e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 CDJ93867.1 - 0.0072 15.8 1.3 0.35 10.2 0.4 2.9 1 1 2 3 3 3 1 Peptidase family C54 TraB PF01963.17 CDJ93868.1 - 1.2e-28 100.7 0.1 1.8e-28 100.2 0.1 1.1 1 0 0 1 1 1 1 TraB family Retrotrans_gag PF03732.17 CDJ93869.1 - 0.0022 18.2 0.1 0.0075 16.5 0.0 2.0 2 1 0 2 2 2 1 Retrotransposon gag protein SCAN PF02023.17 CDJ93869.1 - 0.0046 16.7 0.1 0.018 14.8 0.1 2.1 1 1 0 1 1 1 1 SCAN domain Syntaxin_2 PF14523.6 CDJ93869.1 - 0.11 12.8 1.3 12 6.3 0.0 2.6 2 1 0 2 2 2 0 Syntaxin-like protein Apolipoprotein PF01442.18 CDJ93869.1 - 0.18 11.7 5.7 3.2 7.6 0.1 2.5 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain DUF3439 PF11921.8 CDJ93870.1 - 0.065 13.2 0.2 0.084 12.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pkinase_Tyr PF07714.17 CDJ93871.1 - 3.5e-74 249.4 0.0 4.5e-74 249.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ93871.1 - 1.2e-41 142.9 0.0 1.9e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ93871.1 - 0.017 14.4 0.0 0.055 12.8 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 CDJ93871.1 - 0.19 11.1 0.7 0.5 9.7 0.7 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PhyH PF05721.13 CDJ93872.1 - 2.1e-57 194.8 0.0 2.5e-57 194.6 0.0 1.0 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RNase_E_G PF10150.9 CDJ93872.1 - 0.072 12.5 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease E/G family DUF2151 PF10221.9 CDJ93873.1 - 0.00013 20.7 0.0 0.00013 20.7 0.0 1.0 1 0 0 1 1 1 1 Cell cycle and development regulator Cas_Csm6 PF09659.10 CDJ93873.1 - 0.055 12.2 0.0 0.059 12.1 0.0 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csm6) DUF2151 PF10221.9 CDJ93874.1 - 1.5e-112 377.4 0.1 7e-73 246.4 0.0 2.0 1 1 1 2 2 2 2 Cell cycle and development regulator PPTA PF01239.22 CDJ93875.1 - 4.2e-44 147.1 11.5 6.3e-09 35.3 0.1 5.7 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_14 PF13428.6 CDJ93875.1 - 0.0013 19.3 0.1 34 5.6 0.0 4.7 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ93875.1 - 0.0014 18.9 1.0 1.6 9.3 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat DEK_C PF08766.11 CDJ93875.1 - 0.022 14.7 0.2 0.059 13.3 0.0 1.9 2 0 0 2 2 2 0 DEK C terminal domain F-box-like_2 PF13013.6 CDJ93875.1 - 0.074 13.0 0.7 4.8 7.2 0.1 2.9 3 0 0 3 3 3 0 F-box-like domain Dor1 PF04124.12 CDJ93876.1 - 8.7e-80 267.9 0.9 8.7e-80 267.9 0.9 1.4 2 0 0 2 2 2 1 Dor1-like family DUF3877 PF12993.7 CDJ93877.1 - 0.061 13.2 0.0 0.78 9.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) YhhN PF07947.14 CDJ93877.1 - 0.11 12.1 0.3 0.28 10.8 0.3 1.6 1 0 0 1 1 1 0 YhhN family DUF4162 PF13732.6 CDJ93878.1 - 0.044 14.5 0.3 2.4 8.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) BTB PF00651.31 CDJ93879.1 - 5.8e-28 97.3 0.1 7.5e-28 97.0 0.1 1.1 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 CDJ93880.1 - 7.4e-11 42.3 0.0 2.1e-10 40.8 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 CDJ93880.1 - 1.1e-09 38.3 0.0 1.1e-08 35.1 0.0 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch Astacin PF01400.24 CDJ93881.1 - 3.5e-60 202.9 0.1 5.2e-60 202.4 0.1 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 CDJ93881.1 - 1.8e-05 24.6 0.2 0.0073 16.2 0.1 2.3 2 0 0 2 2 2 2 Matrixin CUB PF00431.20 CDJ93881.1 - 9.2e-05 22.7 0.1 0.00074 19.8 0.0 2.3 2 0 0 2 2 2 1 CUB domain Reprolysin_3 PF13582.6 CDJ93881.1 - 0.0041 17.6 0.2 0.0097 16.4 0.2 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CDJ93881.1 - 0.012 15.2 0.1 0.02 14.5 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CDJ93881.1 - 0.12 12.5 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 EGF_2 PF07974.13 CDJ93881.1 - 0.69 10.3 10.9 2.1 8.8 10.9 1.9 1 0 0 1 1 1 0 EGF-like domain Med4 PF10018.9 CDJ93882.1 - 0.0018 18.0 3.6 0.0035 17.1 2.4 1.9 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 CEP19 PF14933.6 CDJ93882.1 - 0.16 12.2 4.5 0.28 11.5 4.5 1.3 1 0 0 1 1 1 0 CEP19-like protein DUF1272 PF06906.11 CDJ93882.1 - 5.1 7.3 7.5 14 5.9 3.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) RGCC PF15151.6 CDJ93883.1 - 0.02 15.1 0.1 0.033 14.4 0.1 1.3 1 0 0 1 1 1 0 Response gene to complement 32 protein family Ephrin PF00812.17 CDJ93884.1 - 3.4e-34 117.8 0.0 4.8e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Ephrin U3_assoc_6 PF08640.11 CDJ93885.1 - 0.0017 18.3 0.7 0.0017 18.3 0.7 3.4 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 CDJ93885.1 - 1.6 9.8 6.6 1.2e+02 3.9 0.3 5.1 6 1 2 8 8 8 0 Tetratricopeptide repeat Collagen PF01391.18 CDJ93887.1 - 6.5e-26 89.9 108.4 5.3e-10 38.9 36.3 4.0 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ93887.1 - 1.5e-16 60.1 0.7 2e-16 59.8 0.7 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain 7TM_GPCR_Srsx PF10320.9 CDJ93889.1 - 9.2e-18 64.5 10.4 1e-17 64.4 10.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 CDJ93889.1 - 8.8e-08 31.8 7.0 1e-07 31.6 7.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CDJ93889.1 - 0.015 15.0 13.1 0.018 14.7 13.1 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx PLA2G12 PF06951.11 CDJ93890.1 - 0.0074 16.2 0.3 0.0083 16.0 0.3 1.1 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) DUF1353 PF07087.11 CDJ93890.1 - 0.068 12.9 0.0 0.086 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) Phospholip_A2_2 PF05826.12 CDJ93890.1 - 0.075 13.3 1.8 0.47 10.7 0.2 2.0 1 1 1 2 2 2 0 Phospholipase A2 7TM_GPCR_Srsx PF10320.9 CDJ93891.1 - 0.00023 20.6 4.5 0.0003 20.3 4.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 CDJ93893.1 - 1.8e-13 50.7 0.3 2.4e-13 50.3 0.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx zf-PARP PF00645.18 CDJ93894.1 - 0.012 16.4 0.3 0.012 16.4 0.3 1.7 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region m_DGTX_Dc1a_b_c PF17491.2 CDJ93894.1 - 0.047 14.3 1.5 7.7 7.3 0.1 2.3 2 0 0 2 2 2 0 Spider Toxins mu-diguetoxin-1 a, b and c tRNA-synt_1b PF00579.25 CDJ93895.1 - 5.2e-54 183.6 0.0 8.5e-54 182.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PCI PF01399.27 CDJ93895.1 - 1.5e-13 51.1 0.1 5.2e-13 49.4 0.1 2.0 1 0 0 1 1 1 1 PCI domain eIF3m_C_helix PF18005.1 CDJ93895.1 - 0.0027 17.4 6.2 0.0027 17.4 6.2 1.8 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix DUF5563 PF17718.1 CDJ93899.1 - 0.14 11.7 1.5 0.19 11.3 1.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5563) HLH PF00010.26 CDJ93901.1 - 2.5e-15 56.1 1.1 4.3e-15 55.4 1.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SieB PF14163.6 CDJ93901.1 - 0.015 14.8 1.0 0.023 14.2 1.0 1.3 1 0 0 1 1 1 0 Super-infection exclusion protein B YjeF_N PF03853.15 CDJ93902.1 - 9.1e-39 133.1 0.0 1.1e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Pkinase PF00069.25 CDJ93903.1 - 1.8e-67 227.5 0.0 2.2e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ93903.1 - 2.5e-26 92.5 0.0 5e-26 91.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ93903.1 - 6.5e-07 28.9 0.0 0.00031 20.1 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CDJ93903.1 - 0.0088 16.0 0.0 0.032 14.1 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDJ93903.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 CDJ93903.1 - 0.037 13.4 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_lid_7 PF17867.1 CDJ93905.1 - 0.37 11.0 2.5 4.2 7.6 0.1 3.4 3 1 1 4 4 4 0 Midasin AAA lid domain NINJA_B PF16136.5 CDJ93905.1 - 3.5 8.0 6.0 13 6.2 0.0 3.1 3 0 0 3 3 3 0 Putative nuclear localisation signal Neuralized PF07177.12 CDJ93906.1 - 5.1e-30 104.5 0.0 6.4e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Neuralized DHFR_1 PF00186.19 CDJ93907.1 - 3.7e-36 124.3 0.0 4.4e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase CBM_10 PF02013.16 CDJ93908.1 - 0.43 11.1 3.1 16 6.0 0.2 2.5 2 0 0 2 2 2 0 Cellulose or protein binding domain zf-RING_UBOX PF13445.6 CDJ93909.1 - 1.3e-06 28.3 3.2 1.3e-06 28.3 3.2 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 CDJ93909.1 - 2.6e-06 27.7 7.5 2.6e-06 27.7 7.5 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 CDJ93909.1 - 9e-05 22.4 5.8 9e-05 22.4 5.8 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CDJ93909.1 - 0.00063 19.6 6.2 0.00063 19.6 6.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ93909.1 - 0.00095 19.3 7.7 0.00095 19.3 7.7 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 CDJ93909.1 - 0.0032 17.4 4.2 0.0063 16.5 3.5 1.8 1 1 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_2 PF13923.6 CDJ93909.1 - 0.011 15.6 4.3 0.011 15.6 4.3 2.1 2 1 1 3 3 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CDJ93909.1 - 0.37 11.0 4.3 0.97 9.6 4.3 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 CDJ93909.1 - 0.41 10.5 12.0 0.14 12.1 7.2 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CDJ93909.1 - 1.1 9.5 5.4 3.9 7.8 5.4 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain FANCL_C PF11793.8 CDJ93909.1 - 6.3 7.0 7.9 0.2 11.9 1.4 1.9 2 0 0 2 2 1 0 FANCL C-terminal domain zf-U1 PF06220.12 CDJ93909.1 - 8 6.3 8.3 0.71 9.7 3.4 1.8 2 0 0 2 2 2 0 U1 zinc finger Peptidase_A22B PF04258.13 CDJ93910.1 - 2.2e-62 211.2 19.6 3.3e-62 210.6 19.6 1.2 1 0 0 1 1 1 1 Signal peptide peptidase DUF5113 PF17140.4 CDJ93910.1 - 0.045 13.6 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) zf-Tim10_DDP PF02953.15 CDJ93911.1 - 2.4e-24 84.7 4.3 3.4e-24 84.3 4.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Gp-FAR-1 PF05823.12 CDJ93911.1 - 0.032 14.6 0.5 0.057 13.8 0.4 1.4 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) CARD_2 PF16739.5 CDJ93911.1 - 0.035 14.1 0.8 0.07 13.1 0.5 1.6 1 1 1 2 2 2 0 Caspase recruitment domain Mt_ATP-synt_B PF05405.14 CDJ93911.1 - 0.13 11.9 3.1 0.17 11.5 3.1 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF3621 PF12285.8 CDJ93911.1 - 0.13 12.7 6.0 0.15 12.4 4.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3621) DUF2605 PF10792.9 CDJ93911.1 - 0.84 9.6 4.0 0.44 10.5 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) Peptidase_M24 PF00557.24 CDJ93912.1 - 9.5e-59 198.6 0.1 1.3e-58 198.1 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CDJ93912.1 - 1.4e-23 83.0 0.0 3.8e-23 81.5 0.0 1.8 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_M24 PF00557.24 CDJ93913.1 - 2.2e-59 200.7 0.1 8.7e-59 198.7 0.1 1.8 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.16 CDJ93913.1 - 3.5e-24 84.9 0.0 8.5e-24 83.6 0.0 1.7 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Collagen PF01391.18 CDJ93914.1 - 2.4e-22 78.4 93.0 4.5e-10 39.1 35.0 4.6 3 1 2 5 5 5 4 Collagen triple helix repeat (20 copies) Collagen PF01391.18 CDJ93915.1 - 3.6e-22 77.9 102.5 4.5e-06 26.3 42.0 4.0 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ93915.1 - 2.6e-14 53.0 0.0 3.3e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain DUF4706 PF15797.5 CDJ93915.1 - 0.082 13.4 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4706) Collagen PF01391.18 CDJ93916.1 - 2.1e-20 72.2 75.2 6.4e-11 41.8 23.3 3.7 2 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ93916.1 - 4.5e-07 29.8 0.6 5.9e-07 29.5 0.6 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Motile_Sperm PF00635.26 CDJ93918.1 - 1.3e-19 70.1 0.0 1.8e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Neur_chan_LBD PF02931.23 CDJ93919.1 - 1.3e-42 145.7 5.9 1.7e-42 145.3 5.9 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ93919.1 - 6.2e-23 82.1 0.1 1.7e-21 77.4 0.0 2.1 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Fn3-like PF14310.6 CDJ93919.1 - 0.061 13.4 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Fibronectin type III-like domain Pkinase PF00069.25 CDJ93920.1 - 2.6e-07 30.3 0.0 4.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ93920.1 - 0.00035 19.9 0.0 0.00062 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase TMEM237 PF15383.6 CDJ93921.1 - 2.3e-15 56.4 0.6 3.2e-15 55.9 0.6 1.2 1 0 0 1 1 1 1 Transmembrane protein 237 MerR-DNA-bind PF09278.11 CDJ93922.1 - 0.0023 18.4 1.4 0.0023 18.4 1.4 1.6 2 0 0 2 2 2 1 MerR, DNA binding DUF3450 PF11932.8 CDJ93922.1 - 0.0041 16.4 6.5 0.0045 16.3 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) SHE3 PF17078.5 CDJ93922.1 - 0.02 14.6 5.3 0.025 14.3 5.1 1.3 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF1204 PF06721.11 CDJ93922.1 - 0.022 14.2 8.4 0.025 14.0 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) GAS PF13851.6 CDJ93922.1 - 0.028 13.8 9.0 0.035 13.4 9.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding PI3K_P85_iSH2 PF16454.5 CDJ93922.1 - 0.057 13.0 10.2 0.081 12.5 10.2 1.3 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain THOC7 PF05615.13 CDJ93922.1 - 0.061 13.6 9.3 0.082 13.2 8.5 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 Nup188_C PF18378.1 CDJ93922.1 - 0.13 11.1 2.3 0.14 11.0 2.3 1.1 1 0 0 1 1 1 0 Nuclear pore protein NUP188 C-terminal domain DUF1664 PF07889.12 CDJ93922.1 - 0.16 12.0 2.5 0.17 11.9 1.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) YabA PF06156.13 CDJ93922.1 - 0.2 12.3 4.8 0.22 12.2 4.8 1.2 1 0 0 1 1 1 0 Initiation control protein YabA DUF724 PF05266.14 CDJ93922.1 - 0.21 11.4 8.3 0.26 11.1 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) OEP PF02321.18 CDJ93922.1 - 0.25 11.1 6.4 0.28 11.0 6.4 1.0 1 0 0 1 1 1 0 Outer membrane efflux protein Atg14 PF10186.9 CDJ93922.1 - 0.3 10.1 9.1 0.32 10.0 9.1 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 CDJ93922.1 - 0.36 10.0 4.4 0.61 9.3 4.4 1.4 1 1 0 1 1 1 0 TMPIT-like protein HAUS6_N PF14661.6 CDJ93922.1 - 0.4 10.2 5.7 0.51 9.9 5.7 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus APG6_N PF17675.1 CDJ93922.1 - 0.44 11.1 12.1 1.3 9.6 12.1 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF3287 PF11690.8 CDJ93922.1 - 0.49 10.1 5.9 0.63 9.8 5.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) OmpH PF03938.14 CDJ93922.1 - 0.6 10.5 8.6 0.73 10.2 8.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Nup88 PF10168.9 CDJ93922.1 - 0.86 7.3 9.2 0.88 7.3 9.2 1.0 1 0 0 1 1 1 0 Nuclear pore component DUF4407 PF14362.6 CDJ93922.1 - 0.91 8.8 5.3 1 8.6 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 CDJ93922.1 - 1.4 8.8 8.7 1.2 8.9 4.2 2.1 1 1 1 2 2 2 0 Septum formation initiator Ribosomal_S24e PF01282.19 CDJ93923.1 - 1.8e-36 124.0 0.1 2.8e-36 123.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Ribosomal_L23 PF00276.20 CDJ93923.1 - 0.48 10.8 5.9 8.8 6.8 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L23 EF-hand_7 PF13499.6 CDJ93924.1 - 1.4e-08 35.0 1.2 1.4e-08 35.0 1.2 3.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ93924.1 - 1.6e-08 33.8 1.0 0.00018 21.1 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CDJ93924.1 - 0.0063 16.0 8.7 0.14 11.7 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 CDJ93924.1 - 0.064 12.8 8.8 0.46 10.1 0.1 3.5 4 0 0 4 4 4 0 EF hand Ribosomal_S13 PF00416.22 CDJ93924.1 - 1.6 9.1 8.7 2.4 8.6 3.7 3.0 2 1 1 3 3 3 0 Ribosomal protein S13/S18 Rx_N PF18052.1 CDJ93924.1 - 1.7 9.0 13.1 1.3 9.3 0.1 2.9 3 0 0 3 3 3 0 Rx N-terminal domain Arm PF00514.23 CDJ93927.1 - 1.5e-14 53.4 2.2 0.0079 16.2 0.3 6.5 6 0 0 6 6 6 5 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 CDJ93927.1 - 0.0076 16.3 0.8 0.14 12.1 0.0 3.3 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Arm_2 PF04826.13 CDJ93927.1 - 0.052 13.0 2.1 0.57 9.6 0.1 3.1 3 0 0 3 3 3 0 Armadillo-like Vac7 PF12751.7 CDJ93927.1 - 3.3 7.0 5.8 0.25 10.7 0.3 1.8 2 0 0 2 2 2 0 Vacuolar segregation subunit 7 ELO PF01151.18 CDJ93928.1 - 5.8e-61 206.2 20.7 7.5e-61 205.8 20.7 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Bap31 PF05529.12 CDJ93930.1 - 0.043 13.7 0.1 0.048 13.5 0.1 1.2 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region Orf78 PF06024.12 CDJ93930.1 - 0.044 14.1 0.7 0.064 13.6 0.4 1.4 1 1 0 1 1 1 0 Orf78 (ac78) C2 PF00168.30 CDJ93931.1 - 2.8e-53 178.5 0.4 5.4e-27 94.1 0.0 2.1 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 CDJ93931.1 - 8.3e-05 22.2 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 2 CEP76 C2 domain Transglut_C PF00927.22 CDJ93931.1 - 0.00036 20.6 0.4 0.18 11.9 0.0 2.4 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain DOCK-C2 PF14429.6 CDJ93931.1 - 0.0074 16.1 0.1 0.37 10.6 0.0 2.1 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins RRM_1 PF00076.22 CDJ93932.1 - 1.5e-23 82.4 0.0 1.7e-23 82.2 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ93932.1 - 0.015 15.2 0.0 0.031 14.1 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_5 PF13893.6 CDJ93932.1 - 0.045 13.4 0.0 0.045 13.3 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pyr_redox_dim PF02852.22 CDJ93932.1 - 0.058 13.7 0.0 0.067 13.5 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain RRM_1 PF00076.22 CDJ93933.1 - 2.3e-23 81.8 0.0 2.6e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ93933.1 - 0.0053 16.3 0.0 0.0057 16.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_9 PF18444.1 CDJ93933.1 - 0.021 14.6 0.4 0.058 13.3 0.4 1.7 1 1 0 1 1 1 0 RNA recognition motif Pyr_redox_dim PF02852.22 CDJ93933.1 - 0.053 13.8 0.0 0.061 13.6 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain RRM_occluded PF16842.5 CDJ93933.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_1 PF00076.22 CDJ93934.1 - 3.3e-24 84.5 0.0 3.9e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ93934.1 - 0.01 15.7 0.0 0.02 14.7 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif Pyr_redox_dim PF02852.22 CDJ93934.1 - 0.019 15.2 0.0 0.021 15.1 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain RRM_5 PF13893.6 CDJ93934.1 - 0.062 12.9 0.0 0.069 12.7 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TNFR_16_TM PF18422.1 CDJ93935.1 - 0.11 12.5 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain GBP_C PF02841.14 CDJ93936.1 - 4.1e-06 26.4 9.7 1.2e-05 24.9 9.7 1.7 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain zf-C2H2_4 PF13894.6 CDJ93936.1 - 7.2e-05 23.3 33.0 0.2 12.6 0.2 7.5 7 0 0 7 7 7 4 C2H2-type zinc finger zf-Di19 PF05605.12 CDJ93936.1 - 0.0052 17.0 14.2 3.5 8.0 0.1 5.1 4 1 0 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-RING_13 PF17977.1 CDJ93936.1 - 0.12 12.5 0.3 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf_C2H2_ZHX PF18387.1 CDJ93936.1 - 1.7 8.4 8.1 35 4.1 0.1 4.5 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain C1_2 PF03107.16 CDJ93936.1 - 3 8.2 20.8 4.2 7.8 0.7 6.2 6 1 0 6 6 6 0 C1 domain SPATA9 PF15824.5 CDJ93936.1 - 3.7 6.8 7.2 7.1 5.8 7.2 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 9 zf-C2H2_2 PF12756.7 CDJ93936.1 - 9.4 6.6 23.7 7.2 7.0 2.8 5.8 2 2 3 5 5 5 0 C2H2 type zinc-finger (2 copies) NPR2 PF06218.11 CDJ93937.1 - 9.8e-13 47.6 0.2 1.1e-12 47.4 0.2 1.2 1 0 0 1 1 1 1 Nitrogen permease regulator 2 Afi1 PF07792.12 CDJ93937.1 - 0.0014 19.1 0.0 0.0018 18.8 0.0 1.2 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking PIG-F PF06699.11 CDJ93938.1 - 1.9e-16 60.8 4.0 2e-16 60.7 4.0 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF456 PF04306.13 CDJ93938.1 - 0.00023 21.4 0.1 0.00028 21.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Rick_17kDa_Anti PF05433.15 CDJ93938.1 - 0.014 15.3 0.7 0.047 13.6 0.0 1.9 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 CDJ93938.1 - 0.018 15.0 4.9 0.39 10.8 1.8 2.1 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_OmpA PF13436.6 CDJ93938.1 - 0.068 13.0 4.5 0.083 12.7 0.9 2.0 2 0 0 2 2 2 0 Glycine-zipper domain Transgly_assoc PF04226.13 CDJ93938.1 - 0.38 11.1 5.9 3.1 8.1 6.1 2.0 1 1 1 2 2 2 0 Transglycosylase associated protein Gly-zipper_YMGG PF13441.6 CDJ93938.1 - 0.69 9.7 5.6 0.29 10.9 1.8 1.9 2 0 0 2 2 2 0 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.9 CDJ93938.1 - 8.1 6.7 9.0 62 3.8 9.0 2.0 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide YusW PF14039.6 CDJ93939.1 - 0.05 14.1 1.1 0.07 13.6 0.2 1.7 2 0 0 2 2 2 0 YusW-like protein HTH_6 PF01418.17 CDJ93939.1 - 0.11 12.5 0.3 0.18 11.8 0.3 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family ZapA PF05164.13 CDJ93939.1 - 0.18 12.3 4.9 0.096 13.1 2.4 1.8 2 0 0 2 2 2 0 Cell division protein ZapA RT_RNaseH PF17917.1 CDJ93940.1 - 4.1e-33 113.8 0.0 1.3e-32 112.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ93940.1 - 1.6e-30 105.1 0.0 3.9e-30 103.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ93940.1 - 8.1e-29 100.7 0.1 1.5e-28 99.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDJ93940.1 - 1.6e-18 67.0 0.0 3.4e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ93940.1 - 4.1e-16 58.8 0.4 8.7e-16 57.8 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CDJ93940.1 - 0.14 11.9 0.0 0.64 9.8 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain YEATS PF03366.16 CDJ93941.1 - 1.6e-32 111.3 1.5 2.4e-32 110.7 1.5 1.2 1 0 0 1 1 1 1 YEATS family UNC119_bdg PF15435.6 CDJ93943.1 - 0.068 12.7 0.2 0.098 12.2 0.2 1.2 1 0 0 1 1 1 0 UNC119-binding protein C5orf30 homologue APG5 PF04106.12 CDJ93944.1 - 3.8e-07 29.9 1.1 3.6e-06 26.7 0.1 1.9 1 1 1 2 2 2 2 Autophagy protein Apg5 dCMP_cyt_deam_1 PF00383.23 CDJ93945.1 - 1.9e-09 37.3 0.0 2.6e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CDJ93945.1 - 0.0075 16.0 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase Aldedh PF00171.22 CDJ93947.1 - 9.8e-159 528.7 0.0 1.1e-158 528.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase PF00069.25 CDJ93948.1 - 3.1e-73 246.4 0.0 4.6e-73 245.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ93948.1 - 1.2e-41 142.7 0.0 1.7e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ93948.1 - 6.5e-08 32.2 0.0 1.2e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like KA1 PF02149.19 CDJ93948.1 - 1.2e-07 31.4 0.2 2.8e-07 30.2 0.2 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 RIO1 PF01163.22 CDJ93948.1 - 5.1e-05 23.0 0.3 0.00012 21.7 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 CDJ93948.1 - 0.00011 21.6 0.1 0.00019 20.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ93948.1 - 0.00092 19.2 0.1 0.007 16.3 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDJ93948.1 - 0.0086 15.7 0.8 0.061 12.9 0.0 2.5 3 0 0 3 3 3 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 CDJ93948.1 - 0.033 13.1 0.1 0.059 12.3 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain PPO1_DWL PF12142.8 CDJ93948.1 - 0.088 12.6 0.1 0.23 11.3 0.1 1.7 1 0 0 1 1 1 0 Polyphenol oxidase middle domain Asp PF00026.23 CDJ93950.1 - 3.6e-85 286.1 2.0 4.1e-85 286.0 2.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ93950.1 - 2.2e-11 44.3 7.6 9e-11 42.3 4.3 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ93950.1 - 0.00011 22.0 0.0 0.00068 19.4 0.0 2.2 2 1 1 3 3 3 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CDJ93950.1 - 0.0019 18.8 0.2 4.2 8.1 0.1 2.9 3 0 0 3 3 3 2 Aspartyl protease Phage_connector PF05352.12 CDJ93950.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Phage Connector (GP10) Peptidase_M24 PF00557.24 CDJ93951.1 - 4.4e-44 150.7 0.1 5.7e-44 150.3 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 CDT1_C PF16679.5 CDJ93951.1 - 0.093 13.2 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain DEAD PF00270.29 CDJ93952.1 - 1.3e-39 135.7 1.2 1.4e-38 132.5 0.3 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ93952.1 - 3.3e-20 72.5 0.4 2.5e-19 69.7 0.0 2.7 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ93952.1 - 2e-07 31.2 0.0 6.9e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CDJ93952.1 - 0.0034 17.7 0.2 0.0062 16.9 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ93952.1 - 0.0037 17.0 0.1 0.0086 15.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 CDJ93952.1 - 0.056 12.9 0.2 0.056 12.9 0.2 3.1 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 CDJ93952.1 - 0.058 13.3 0.1 0.31 10.9 0.1 2.3 2 0 0 2 2 2 0 Helicase QueF_N PF14819.6 CDJ93952.1 - 0.083 13.2 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term 7tm_1 PF00001.21 CDJ93953.1 - 0.0017 17.7 5.9 0.0039 16.5 5.9 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pkinase_Tyr PF07714.17 CDJ93954.1 - 1.2e-22 80.5 0.0 1.5e-22 80.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ93954.1 - 0.0034 16.8 0.0 0.0045 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Vps26 PF03643.15 CDJ93955.1 - 1.8e-74 250.2 1.6 2.1e-74 250.0 1.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.22 CDJ93955.1 - 0.0013 19.1 0.1 0.025 15.0 0.1 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CDJ93955.1 - 0.011 15.7 0.3 0.12 12.4 0.0 2.1 1 1 1 2 2 2 0 Arrestin (or S-antigen), N-terminal domain AAA_28 PF13521.6 CDJ93956.1 - 9.3e-21 74.7 0.1 1.9e-20 73.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 CDJ93956.1 - 0.011 14.7 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MFS_1 PF07690.16 CDJ93957.1 - 1.5e-14 53.7 19.7 2.1e-11 43.3 9.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SapB_2 PF03489.17 CDJ93958.1 - 1.8e-18 66.3 11.0 2.9e-08 33.7 0.9 6.0 6 0 0 6 6 6 4 Saposin-like type B, region 2 SapB_1 PF05184.15 CDJ93958.1 - 5e-06 26.4 13.7 8.5e-05 22.5 1.5 5.0 5 0 0 5 5 5 2 Saposin-like type B, region 1 PA28_alpha PF02251.18 CDJ93958.1 - 0.00082 19.4 0.0 0.013 15.5 0.0 2.5 2 0 0 2 2 2 1 Proteasome activator pa28 alpha subunit DUF445 PF04286.12 CDJ93958.1 - 0.25 11.1 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) tRNA-synt_1c_C PF03950.18 CDJ93959.1 - 1e-10 41.8 0.0 1.2e-10 41.6 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain DUF1885 PF08968.10 CDJ93959.1 - 0.091 12.9 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1885) Claudin_3 PF06653.11 CDJ93961.1 - 6.4e-10 39.2 15.2 5.6e-06 26.4 3.0 2.1 1 1 1 2 2 2 2 Tight junction protein, Claudin-like Claudin_2 PF13903.6 CDJ93961.1 - 7.5e-05 22.6 12.8 0.00016 21.5 8.3 2.0 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.12 CDJ93961.1 - 0.0054 16.2 16.2 0.0092 15.5 11.2 2.0 1 1 1 2 2 2 1 Clc-like PMP22_Claudin PF00822.20 CDJ93961.1 - 0.069 13.0 15.1 0.28 11.0 15.1 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Sec62 PF03839.16 CDJ93961.1 - 2.7 7.5 4.6 1.6 8.2 2.6 1.6 1 1 0 1 1 1 0 Translocation protein Sec62 Peptidase_U4 PF03419.13 CDJ93961.1 - 8.1 5.6 10.9 2.5 7.3 8.1 1.5 1 1 0 1 1 1 0 Sporulation factor SpoIIGA ArAE_2_N PF10337.9 CDJ93961.1 - 9.8 5.1 8.6 14 4.6 8.6 1.5 1 1 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Hyccin PF09790.9 CDJ93962.1 - 7.9e-71 238.8 0.4 1e-70 238.4 0.4 1.1 1 0 0 1 1 1 1 Hyccin Mpp10 PF04006.12 CDJ93962.1 - 0.032 12.7 3.8 0.047 12.1 3.8 1.1 1 0 0 1 1 1 0 Mpp10 protein RVT_1 PF00078.27 CDJ93964.1 - 3.7e-44 150.9 0.1 6.5e-30 104.3 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDJ93964.1 - 2.4e-38 130.2 0.1 7.2e-32 109.4 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ93964.1 - 6e-34 116.5 0.0 1.3e-33 115.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase HOCHOB PF17943.1 CDJ93964.1 - 0.0067 17.1 0.2 7.6 7.3 0.0 2.7 2 0 0 2 2 2 2 Homeobox-cysteine loop-homeobox Peptidase_A17 PF05380.13 CDJ93964.1 - 0.0072 16.4 0.0 0.065 13.2 0.0 2.2 2 0 0 2 2 2 1 Pao retrotransposon peptidase NDK PF00334.19 CDJ93964.1 - 0.013 15.5 0.4 19 5.3 0.0 3.8 5 0 0 5 5 5 0 Nucleoside diphosphate kinase DUF3368 PF11848.8 CDJ93964.1 - 0.033 14.0 0.2 17 5.3 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3368) zf-PARP PF00645.18 CDJ93964.1 - 0.051 14.4 3.2 20 6.1 0.0 3.9 4 0 0 4 4 4 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region MFAP1 PF06991.11 CDJ93965.1 - 1.1e-30 107.1 29.1 1.1e-30 107.1 29.1 2.5 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing GCFC PF07842.12 CDJ93966.1 - 2.6e-08 33.8 2.2 1.8e-06 27.8 0.0 3.2 2 1 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein Cullin PF00888.22 CDJ93967.1 - 2.1e-17 63.0 0.0 3.4e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 CDJ93967.1 - 1.6e-07 31.7 0.0 1.9e-06 28.2 0.0 2.7 3 0 0 3 3 3 1 Anaphase promoting complex (APC) subunit 2 HTH_23 PF13384.6 CDJ93967.1 - 0.027 14.3 0.7 0.027 14.3 0.7 2.1 2 0 0 2 2 2 0 Homeodomain-like domain Sigma70_r4 PF04545.16 CDJ93967.1 - 0.043 13.3 0.2 0.043 13.3 0.2 2.1 3 0 0 3 3 3 0 Sigma-70, region 4 DUF4208 PF13907.6 CDJ93967.1 - 0.12 12.8 0.0 7.1 7.1 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4208) HTH_8 PF02954.19 CDJ93967.1 - 0.12 12.1 0.1 27 4.6 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family MarR_2 PF12802.7 CDJ93967.1 - 0.14 12.1 0.0 0.49 10.3 0.0 1.9 2 0 0 2 2 2 0 MarR family Ribosomal_S25 PF03297.15 CDJ93967.1 - 0.15 12.3 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 S25 ribosomal protein SH3_9 PF14604.6 CDJ93968.1 - 3.1e-11 42.9 0.1 5.5e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDJ93968.1 - 4.1e-07 29.5 0.0 6.4e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDJ93968.1 - 0.00064 19.3 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain VraX PF17412.2 CDJ93969.1 - 0.057 13.1 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function DUF1298 PF06974.13 CDJ93969.1 - 0.11 12.5 0.0 0.53 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1298) Thioredoxin_8 PF13905.6 CDJ93970.1 - 3.9e-22 78.4 0.0 1.1e-20 73.7 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 CDJ93970.1 - 1.4e-05 25.0 0.0 2.9e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDJ93970.1 - 1.4e-05 24.8 0.0 3.6e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 CDJ93970.1 - 0.00029 20.8 0.5 0.11 12.5 0.2 3.0 2 1 0 3 3 3 1 Thioredoxin Thioredoxin_2 PF13098.6 CDJ93970.1 - 0.0016 18.9 0.0 0.019 15.4 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CDJ93970.1 - 0.012 15.4 0.0 0.089 12.6 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin ORF_12_N PF18042.1 CDJ93970.1 - 0.098 13.1 0.0 0.29 11.6 0.0 1.8 2 0 0 2 2 2 0 ORF 12 gene product N-terminal TPR_1 PF00515.28 CDJ93971.1 - 9.5e-18 63.2 6.6 0.0013 18.4 0.0 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ93971.1 - 4e-17 60.9 12.0 0.0017 18.4 0.0 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ93971.1 - 9.4e-15 53.5 15.6 0.0093 16.0 0.0 7.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ93971.1 - 1.4e-11 44.8 5.0 4.6e-05 24.0 0.2 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ93971.1 - 1.2e-09 38.3 4.9 0.00021 21.5 0.8 6.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ93971.1 - 2e-09 37.0 0.1 8.5e-05 22.2 0.0 3.6 3 0 0 3 3 3 2 TPR repeat TPR_7 PF13176.6 CDJ93971.1 - 3.1e-09 36.2 5.9 0.18 11.9 0.7 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ93971.1 - 4e-09 36.5 10.9 0.1 13.5 0.0 6.9 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ93971.1 - 4.4e-07 30.3 9.2 3 8.4 0.0 6.8 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ93971.1 - 3.3e-06 27.1 0.5 0.21 12.1 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ93971.1 - 0.00019 21.5 2.7 0.22 11.7 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ93971.1 - 0.0016 18.9 15.9 0.028 15.0 1.9 6.1 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 CDJ93971.1 - 0.0031 16.8 2.3 0.048 12.9 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat NARP1 PF12569.8 CDJ93971.1 - 0.0081 15.1 0.2 0.047 12.6 0.4 2.1 3 0 0 3 3 3 1 NMDA receptor-regulated protein 1 ANAPC8 PF04049.13 CDJ93971.1 - 0.011 15.8 1.3 0.1 12.6 0.0 2.8 3 0 0 3 3 3 0 Anaphase promoting complex subunit 8 / Cdc23 RPN7 PF10602.9 CDJ93971.1 - 0.12 12.1 2.0 11 5.7 0.8 2.7 1 1 1 2 2 2 0 26S proteasome subunit RPN7 ANAPC3 PF12895.7 CDJ93971.1 - 0.42 10.9 8.0 7 7.0 0.0 4.5 3 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CDJ93971.1 - 1 9.3 10.1 7.4 6.6 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat F-box PF00646.33 CDJ93972.1 - 0.00074 19.3 2.3 0.0032 17.3 1.1 2.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CDJ93972.1 - 0.007 16.2 0.6 0.007 16.2 0.6 2.6 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 CDJ93972.1 - 0.043 14.3 17.7 2.4 8.7 0.4 6.4 4 2 3 7 7 7 0 Leucine Rich repeats (2 copies) DUF4717 PF15838.5 CDJ93972.1 - 0.25 11.4 0.6 0.51 10.4 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4717) Pkinase PF00069.25 CDJ93974.1 - 3.7e-49 167.5 0.0 6.8e-49 166.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ93974.1 - 4.5e-17 62.2 0.0 1.2e-16 60.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ93974.1 - 0.00038 19.9 0.0 0.00081 18.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CDJ93974.1 - 0.002 17.7 0.1 0.0059 16.2 0.1 1.7 1 0 0 1 1 1 1 RIO1 family HTH_17 PF12728.7 CDJ93975.1 - 0.013 15.7 0.6 0.46 10.7 0.1 2.8 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_33 PF13592.6 CDJ93975.1 - 0.051 13.2 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn helix RVT_1 PF00078.27 CDJ93976.1 - 1.4e-07 31.2 0.0 2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) COX16 PF14138.6 CDJ93976.1 - 0.34 11.4 2.2 0.91 10.1 2.1 1.6 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Lectin_C PF00059.21 CDJ93978.1 - 1.7e-07 31.9 0.4 8.3e-07 29.7 0.0 2.4 2 0 0 2 2 2 1 Lectin C-type domain CBM_21 PF03370.13 CDJ93979.1 - 3.1e-27 95.0 0.6 3.1e-27 95.0 0.6 1.5 2 0 0 2 2 2 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CDJ93979.1 - 7.5e-12 45.7 1.0 1.3e-11 44.9 1.0 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) R3H-assoc PF13902.6 CDJ93980.1 - 0.039 14.3 4.4 0.085 13.2 4.4 1.5 1 0 0 1 1 1 0 R3H-associated N-terminal domain 7TM_GPCR_Srw PF10324.9 CDJ93981.1 - 1.2e-07 31.4 8.6 2.2e-07 30.5 8.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 CDJ93981.1 - 0.00028 20.4 13.3 0.001 18.5 13.3 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 CDJ93981.1 - 0.019 14.3 11.7 0.028 13.7 11.7 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Sin3a_C PF16879.5 CDJ93983.1 - 7.4e-06 25.9 0.4 1.7e-05 24.7 0.4 1.8 1 1 0 1 1 1 1 C-terminal domain of Sin3a protein DUF4337 PF14235.6 CDJ93985.1 - 5.3 7.1 6.6 8.1 6.5 6.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) Nuc_sug_transp PF04142.15 CDJ93986.1 - 7.3e-112 373.6 21.1 8.7e-112 373.3 21.1 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CDJ93986.1 - 1e-05 25.7 2.9 1e-05 25.7 2.9 2.9 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 CDJ93986.1 - 0.00047 19.5 21.5 0.0011 18.2 21.6 1.6 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 CDJ93986.1 - 0.044 13.0 26.4 0.24 10.6 26.4 2.0 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport HrpB2 PF09487.10 CDJ93986.1 - 0.16 12.4 0.0 0.29 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) ARF7EP_C PF14949.6 CDJ93987.1 - 4.6e-26 91.5 6.3 4.6e-26 91.5 6.3 1.5 2 0 0 2 2 2 1 ARF7 effector protein C-terminus Torus PF16131.5 CDJ93988.1 - 0.08 13.6 0.0 0.12 13.1 0.0 1.3 1 0 0 1 1 1 0 Torus domain RT_RNaseH_2 PF17919.1 CDJ93989.1 - 5.7e-34 116.1 0.0 1.2e-33 115.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ93989.1 - 7.9e-31 106.5 0.0 1.3e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ93989.1 - 1.7e-08 34.2 0.0 2.9e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDJ93989.1 - 7.4e-05 22.9 0.2 0.00026 21.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 CDJ93989.1 - 0.0001 22.0 0.0 0.00031 20.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_1_7 PF13843.6 CDJ93991.1 - 1.4e-12 47.6 0.0 2e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 DUF229 PF02995.17 CDJ93992.1 - 6.6e-54 183.3 2.1 8.7e-54 182.9 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 CDJ93992.1 - 0.0087 15.5 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Peptidase_C3G PF12381.8 CDJ93992.1 - 0.098 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Tungro spherical virus-type peptidase gerPA PF10676.9 CDJ93993.1 - 0.007 16.6 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 Spore germination protein gerPA/gerPF SLC3A2_N PF16028.5 CDJ93993.1 - 0.055 13.0 0.4 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus CAP PF00188.26 CDJ93994.1 - 0.0019 19.0 0.1 0.0025 18.6 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF2569 PF10754.9 CDJ93995.1 - 0.21 12.0 18.2 0.5 10.8 18.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) Per1 PF04080.13 CDJ93995.1 - 0.58 9.9 6.1 0.7 9.6 6.1 1.1 1 0 0 1 1 1 0 Per1-like family Peptidase_U4 PF03419.13 CDJ93995.1 - 0.67 9.2 15.3 0.88 8.8 15.3 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF2070 PF09843.9 CDJ93995.1 - 4.2 5.5 16.8 6.7 4.9 16.8 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Linker_histone PF00538.19 CDJ93996.1 - 4e-09 36.7 1.6 4e-09 36.7 1.6 1.8 2 0 0 2 2 2 1 linker histone H1 and H5 family RHH_1 PF01402.21 CDJ93996.1 - 0.076 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family XRN_M PF17846.1 CDJ93996.1 - 3.4 6.5 6.3 3.8 6.4 6.3 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Linker_histone PF00538.19 CDJ93997.1 - 7.1e-22 77.6 1.2 7.1e-22 77.6 1.2 1.8 2 0 0 2 2 2 1 linker histone H1 and H5 family RHH_1 PF01402.21 CDJ93997.1 - 0.023 14.6 0.0 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Actin PF00022.19 CDJ93998.1 - 6.1e-43 147.0 0.0 2.9e-42 144.7 0.0 1.7 1 1 0 1 1 1 1 Actin PilM_2 PF11104.8 CDJ93998.1 - 0.002 17.2 0.1 0.025 13.6 0.0 2.1 2 0 0 2 2 2 1 Type IV pilus assembly protein PilM; MreB_Mbl PF06723.13 CDJ93998.1 - 0.044 12.6 0.2 1 8.1 0.0 2.3 2 1 0 2 2 2 0 MreB/Mbl protein DUF4714 PF15833.5 CDJ93998.1 - 0.073 13.0 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4714) Hydantoinase_B PF02538.14 CDJ93999.1 - 7.9e-213 707.5 0.1 1.1e-212 707.1 0.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 CDJ93999.1 - 3.5e-105 351.4 0.4 3.5e-105 351.4 0.4 2.3 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 CDJ93999.1 - 1.3e-60 204.1 0.2 1.6e-58 197.4 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Spidroin_MaSp PF11260.8 CDJ93999.1 - 0.059 13.7 0.1 0.2 12.0 0.1 1.9 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 Asp_protease_2 PF13650.6 CDJ94000.1 - 3.7e-07 30.7 0.1 5.3e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ94000.1 - 5.7e-07 30.0 0.0 9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ94000.1 - 2.7e-05 24.4 0.0 6.7e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ94000.1 - 0.0019 18.0 0.0 0.0038 17.0 0.0 1.5 1 1 0 1 1 1 1 Aspartyl protease HTH_Tnp_Tc3_2 PF01498.18 CDJ94001.1 - 3.3e-25 88.1 0.4 7.1e-25 87.1 0.4 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 CDJ94001.1 - 5.5e-12 45.7 0.0 1.1e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 CDJ94001.1 - 2.8e-06 27.9 7.0 1.8e-05 25.3 0.4 2.7 1 1 1 2 2 2 1 Homeodomain-like domain PAX PF00292.18 CDJ94001.1 - 0.00032 20.6 0.2 0.0005 20.0 0.2 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_24 PF13412.6 CDJ94001.1 - 0.031 13.8 0.9 0.93 9.1 0.0 2.9 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 CDJ94001.1 - 0.21 11.4 0.1 0.21 11.4 0.1 2.9 4 0 0 4 4 4 0 Homeodomain-like domain Beta-lactamase PF00144.24 CDJ94002.1 - 2e-69 234.3 0.0 2.4e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase tRNA-synt_1 PF00133.22 CDJ94003.1 - 8.8e-222 737.6 0.0 1.6e-221 736.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDJ94003.1 - 3.5e-24 85.5 0.0 6.2e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CDJ94003.1 - 3.2e-11 42.6 0.1 0.014 14.2 0.0 3.5 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CDJ94003.1 - 0.014 14.7 0.0 0.039 13.3 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain HMG_box_2 PF09011.10 CDJ94004.1 - 7.4e-17 61.7 15.9 2.1e-12 47.4 0.4 3.4 2 1 1 3 3 3 2 HMG-box domain HMG_box PF00505.19 CDJ94004.1 - 6.1e-13 49.0 20.8 4.9e-10 39.7 1.6 3.6 2 1 1 3 3 3 2 HMG (high mobility group) box Aldedh PF00171.22 CDJ94004.1 - 0.084 11.4 2.9 0.7 8.3 0.1 2.1 2 0 0 2 2 2 0 Aldehyde dehydrogenase family DUF2582 PF10771.9 CDJ94004.1 - 0.086 13.0 1.8 0.43 10.8 1.8 2.1 1 1 0 1 1 1 0 Winged helix-turn-helix domain (DUF2582) DUF4872 PF16169.5 CDJ94004.1 - 0.1 12.4 1.3 2.8 7.7 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4872) DUF3106 PF11304.8 CDJ94004.1 - 0.23 11.9 12.8 2.8 8.5 8.5 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) YABBY PF04690.13 CDJ94004.1 - 0.85 10.2 6.4 0.086 13.4 2.0 1.6 2 0 0 2 2 2 0 YABBY protein Endonuc_Holl PF10107.9 CDJ94004.1 - 3.7 7.4 9.4 3.7 7.4 0.0 2.2 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase FKBP_C PF00254.28 CDJ94005.1 - 2.9e-33 114.0 0.0 4e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ank_2 PF12796.7 CDJ94006.1 - 0.057 14.0 0.0 0.07 13.7 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Peptidase_M1 PF01433.20 CDJ94007.1 - 1.9e-46 158.4 0.2 2.9e-46 157.8 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 CDJ94007.1 - 3.5e-36 123.7 0.0 6.4e-36 122.9 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 CDJ94007.1 - 1.6e-17 64.3 0.0 2.5e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Ribonuclease_T2 PF00445.18 CDJ94007.1 - 0.052 13.8 0.6 0.16 12.2 0.6 1.9 1 1 0 1 1 1 0 Ribonuclease T2 family MATalpha_HMGbox PF04769.12 CDJ94007.1 - 0.058 12.7 0.2 0.11 11.8 0.2 1.4 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Peptidase_M48 PF01435.18 CDJ94007.1 - 0.086 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M48 Peptidase_MA_2 PF13485.6 CDJ94007.1 - 0.11 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase MA superfamily Med14 PF08638.11 CDJ94008.1 - 1.2e-43 148.8 0.2 2.1e-43 148.0 0.2 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 DDT PF02791.17 CDJ94008.1 - 0.094 13.0 0.2 0.76 10.1 0.1 2.5 3 0 0 3 3 3 0 DDT domain Pkinase PF00069.25 CDJ94009.1 - 7.9e-41 140.2 0.3 8.8e-41 140.0 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ94009.1 - 8.6e-20 71.1 0.2 9.5e-20 71.0 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ94009.1 - 0.00026 21.0 0.1 0.21 11.5 0.0 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CDJ94009.1 - 0.0066 15.8 1.0 0.034 13.5 0.1 2.0 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CDJ94009.1 - 0.013 15.0 0.1 0.026 14.0 0.0 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL CbiC PF02570.15 CDJ94009.1 - 0.11 12.2 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Precorrin-8X methylmutase Neur_chan_LBD PF02931.23 CDJ94011.1 - 8.6e-76 254.1 1.6 1.2e-75 253.7 1.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ94011.1 - 7e-41 140.8 15.3 7.5e-31 108.0 11.4 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF2678 PF10856.8 CDJ94011.1 - 0.0061 16.5 2.5 0.014 15.3 2.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) Neur_chan_LBD PF02931.23 CDJ94012.1 - 6.5e-46 156.5 1.3 9.3e-46 156.0 1.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ94012.1 - 6.2e-33 114.8 1.5 7.9e-33 114.5 1.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF4199 PF13858.6 CDJ94012.1 - 0.049 14.0 1.3 0.11 12.9 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Dis3l2_C_term PF17877.1 CDJ94012.1 - 0.054 13.8 0.0 0.21 11.9 0.0 2.0 2 0 0 2 2 2 0 DIS3-like exonuclease 2 C terminal DUF2976 PF11190.8 CDJ94012.1 - 0.09 12.6 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) MIP PF00230.20 CDJ94013.1 - 1.2e-37 129.8 0.7 1.7e-37 129.3 0.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein CTXphi_pIII-N1 PF16710.5 CDJ94013.1 - 0.0046 17.0 0.1 0.95 9.6 0.1 2.5 2 0 0 2 2 2 2 N-terminal N1 domain of Vibrio phage CTXphi pIII SNARE_assoc PF09335.11 CDJ94013.1 - 0.052 14.0 4.7 4.4 7.8 0.4 2.9 3 0 0 3 3 3 0 SNARE associated Golgi protein Ribosomal_L12 PF00542.19 CDJ94016.1 - 9.5e-22 77.1 5.5 1.6e-21 76.4 5.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain PAN_1 PF00024.26 CDJ94017.1 - 4.4e-25 87.4 7.3 2.3e-08 33.9 0.1 3.4 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.6 CDJ94017.1 - 0.025 14.5 8.9 0.78 9.7 0.3 4.0 3 1 0 3 3 3 0 PAN domain PAN_3 PF08277.12 CDJ94017.1 - 0.4 10.5 12.1 0.12 12.3 0.5 4.3 5 1 0 5 5 5 0 PAN-like domain PAN_2 PF08276.11 CDJ94017.1 - 4.1 7.6 9.5 0.34 11.0 0.9 3.4 3 1 0 3 3 3 0 PAN-like domain ShK PF01549.24 CDJ94018.1 - 0.0033 17.9 4.3 0.007 16.9 4.3 1.6 1 0 0 1 1 1 1 ShK domain-like CUB PF00431.20 CDJ94018.1 - 0.011 16.1 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 0 CUB domain CN_hydrolase PF00795.22 CDJ94019.1 - 4.7e-56 190.0 0.0 5.6e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.16 CDJ94021.1 - 8e-30 103.9 33.9 1.3e-29 103.2 33.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily HTH_48 PF17906.1 CDJ94022.1 - 8.3e-19 67.5 1.6 1.5e-18 66.6 1.6 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_Tnp_IS630 PF01710.16 CDJ94022.1 - 3.7e-07 30.2 0.0 4.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 CDJ94022.1 - 2.2e-06 27.3 0.1 0.0094 15.7 0.0 2.4 2 0 0 2 2 2 2 Homeodomain-like domain HTH_32 PF13565.6 CDJ94022.1 - 1.6e-05 25.5 0.1 3.4e-05 24.4 0.0 1.6 2 0 0 2 2 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 CDJ94022.1 - 4e-05 23.8 0.5 8.5e-05 22.7 0.2 1.7 2 0 0 2 2 2 1 Transposase HTH_28 PF13518.6 CDJ94022.1 - 4.9e-05 23.4 0.0 0.45 10.7 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_38 PF13936.6 CDJ94022.1 - 8.6e-05 22.2 0.1 0.0002 21.0 0.0 1.6 2 0 0 2 2 1 1 Helix-turn-helix domain HTH_50 PF18024.1 CDJ94022.1 - 0.00036 20.1 0.0 0.00075 19.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 CDJ94022.1 - 0.0016 18.4 0.0 0.17 11.9 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_11 PF08279.12 CDJ94022.1 - 0.0018 18.2 0.1 0.0031 17.4 0.1 1.3 1 0 0 1 1 1 1 HTH domain HTH_Tnp_1 PF01527.20 CDJ94022.1 - 0.0061 16.8 0.4 4.5 7.7 0.0 2.3 1 1 1 2 2 2 2 Transposase HTH_Tnp_ISL3 PF13542.6 CDJ94022.1 - 0.014 14.8 0.1 0.13 11.7 0.0 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_40 PF14493.6 CDJ94022.1 - 0.016 15.7 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_30 PF13556.6 CDJ94022.1 - 0.025 14.4 0.1 0.049 13.5 0.1 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_6 PF01418.17 CDJ94022.1 - 0.029 14.3 0.0 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family Terminase_5 PF06056.12 CDJ94022.1 - 0.031 14.2 0.0 3.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) IF2_N PF04760.15 CDJ94022.1 - 0.037 13.8 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region DUF488 PF04343.13 CDJ94022.1 - 0.041 14.5 0.0 0.067 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF488 HTH_5 PF01022.20 CDJ94022.1 - 0.041 13.7 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_36 PF13730.6 CDJ94022.1 - 0.049 13.6 0.0 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_10 PF04967.12 CDJ94022.1 - 0.053 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain GerE PF00196.19 CDJ94022.1 - 0.054 13.0 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_24 PF13412.6 CDJ94022.1 - 0.15 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Phage_terminase PF10668.9 CDJ94022.1 - 0.18 11.8 1.0 0.56 10.2 0.2 2.2 2 1 0 2 2 2 0 Phage terminase small subunit Tweety PF04906.13 CDJ94023.1 - 0.24 10.0 0.8 0.32 9.6 0.8 1.1 1 0 0 1 1 1 0 Tweety ALMT PF11744.8 CDJ94023.1 - 0.4 9.5 3.3 0.5 9.1 3.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter NOA36 PF06524.12 CDJ94025.1 - 0.0015 17.9 16.0 0.002 17.5 16.0 1.2 1 0 0 1 1 1 1 NOA36 protein FlaC_arch PF05377.11 CDJ94025.1 - 0.0067 16.8 2.5 1.4 9.4 0.1 2.9 2 1 1 3 3 3 1 Flagella accessory protein C (FlaC) D123 PF07065.14 CDJ94025.1 - 0.0068 15.6 6.2 0.66 9.1 3.9 2.1 2 0 0 2 2 2 2 D123 Sigma70_ner PF04546.13 CDJ94025.1 - 0.014 15.3 15.6 0.29 11.0 0.4 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region PI3K_1B_p101 PF10486.9 CDJ94025.1 - 0.015 13.1 3.8 0.017 12.9 3.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF489 PF04356.12 CDJ94025.1 - 0.047 13.7 0.2 0.064 13.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF5520 PF17658.1 CDJ94025.1 - 0.05 12.7 2.0 0.069 12.2 2.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5520) FAM176 PF14851.6 CDJ94025.1 - 0.15 11.8 8.4 0.21 11.3 3.8 2.2 2 0 0 2 2 2 0 FAM176 family DUF3073 PF11273.8 CDJ94025.1 - 0.28 12.0 11.0 0.73 10.6 11.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3073) DUF2796 PF10986.8 CDJ94025.1 - 0.28 11.1 2.3 0.44 10.5 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) CENP-B_dimeris PF09026.10 CDJ94025.1 - 1.2 9.6 17.3 2.5 8.6 17.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.9 CDJ94025.1 - 4.8 6.2 20.0 0.73 8.9 16.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) DUF4611 PF15387.6 CDJ94025.1 - 7.2 6.9 17.9 7.7 6.8 15.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) Sporozoite_P67 PF05642.11 CDJ94025.1 - 7.5 4.5 10.2 12 3.8 10.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cwf_Cwc_15 PF04889.12 CDJ94025.1 - 8.6 6.0 23.0 13 5.4 23.0 1.4 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF489 PF04356.12 CDJ94026.1 - 0.0005 20.1 0.2 0.0006 19.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF489) DUF3316 PF11777.8 CDJ94026.1 - 0.0068 16.5 0.3 0.01 15.9 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3316) ADPrib_exo_Tox PF03496.14 CDJ94026.1 - 0.0076 15.6 1.9 0.0084 15.5 1.3 1.4 1 1 0 1 1 1 1 ADP-ribosyltransferase exoenzyme Pex19 PF04614.12 CDJ94026.1 - 0.019 14.7 3.8 2.1 8.1 3.8 2.0 1 1 0 1 1 1 0 Pex19 protein family TssO PF17561.2 CDJ94026.1 - 0.049 13.7 0.8 0.11 12.6 0.2 1.8 1 1 0 1 1 1 0 Type VI secretion system, TssO ISG65-75 PF11727.8 CDJ94026.1 - 0.057 12.7 0.3 8.8 5.5 0.0 2.2 2 0 0 2 2 2 0 Invariant surface glycoprotein TBP PF00352.21 CDJ94026.1 - 0.061 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Transcription factor TFIID (or TATA-binding protein, TBP) DUF948 PF06103.11 CDJ94026.1 - 0.063 13.6 1.1 1.6 9.0 0.1 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) ATPase PF06745.13 CDJ94026.1 - 0.1 11.9 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 KaiC PBP1_TM PF14812.6 CDJ94026.1 - 0.38 11.1 8.3 0.13 12.6 5.4 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Syntaxin_2 PF14523.6 CDJ94026.1 - 0.71 10.3 5.9 0.94 9.9 1.5 2.4 1 1 1 2 2 2 0 Syntaxin-like protein PE PF00934.20 CDJ94028.1 - 0.27 11.6 1.9 0.37 11.1 0.2 1.8 1 1 1 2 2 2 0 PE family Profilin PF00235.19 CDJ94029.1 - 0.069 13.4 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Profilin Skp1 PF01466.19 CDJ94033.1 - 0.00042 20.4 0.0 0.00079 19.5 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain HSP70 PF00012.20 CDJ94034.1 - 6.5e-184 612.5 0.2 1.3e-183 611.5 0.0 1.5 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 CDJ94034.1 - 2.1e-06 26.8 0.0 3.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Raco_middle PF17651.1 CDJ94034.1 - 0.017 14.8 0.1 0.092 12.4 0.0 2.2 3 0 0 3 3 3 0 RACo middle region Rac1 PF09632.10 CDJ94034.1 - 0.058 12.6 0.0 7.2 5.7 0.1 2.3 1 1 1 2 2 2 0 Rac1-binding domain Big_5 PF13205.6 CDJ94034.1 - 0.1 13.3 0.2 0.29 11.9 0.2 1.8 1 0 0 1 1 1 0 Bacterial Ig-like domain Rpn3_C PF08375.11 CDJ94035.1 - 2.6e-23 82.2 2.3 7.5e-23 80.7 2.3 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 CDJ94035.1 - 5.6e-21 75.0 0.6 1.2e-20 74.0 0.1 1.8 2 0 0 2 2 2 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 CDJ94035.1 - 0.021 14.8 0.1 0.062 13.3 0.1 1.9 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family Prok-TraM PF09228.10 CDJ94035.1 - 0.024 15.0 0.1 0.11 12.9 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM TPR_2 PF07719.17 CDJ94035.1 - 0.48 10.7 10.3 1.1 9.6 1.6 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ94035.1 - 2.9 8.6 8.6 9.2 7.0 1.6 3.7 3 2 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L32p PF01783.23 CDJ94036.1 - 3.4e-08 33.6 0.4 7.5e-08 32.5 0.4 1.6 1 0 0 1 1 1 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.6 CDJ94036.1 - 0.0016 17.8 1.6 0.003 16.9 1.6 1.3 1 0 0 1 1 1 1 zinc-ribbon domain Prok-RING_1 PF14446.6 CDJ94036.1 - 0.015 15.2 1.4 0.036 14.0 1.4 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 DZR PF12773.7 CDJ94036.1 - 0.063 13.3 1.5 0.22 11.6 1.6 1.6 1 1 0 1 1 1 0 Double zinc ribbon HAD_2 PF13419.6 CDJ94037.1 - 2.1e-09 37.7 0.0 2.5e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDJ94037.1 - 5.8e-06 26.7 0.0 6.6e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CDJ94037.1 - 0.0084 16.2 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Guanylate_cyc PF00211.20 CDJ94039.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain AAA PF00004.29 CDJ94040.1 - 4.8e-16 59.4 0.0 9.7e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ94040.1 - 1.1e-09 38.6 0.0 3.4e-09 37.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 CDJ94040.1 - 4e-09 37.1 0.0 7.9e-08 32.9 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 CDJ94040.1 - 2e-06 27.8 0.0 4.4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 CDJ94040.1 - 8.7e-06 26.1 0.2 4.6e-05 23.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CDJ94040.1 - 1.9e-05 24.1 0.0 3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_lid_10 PF17872.1 CDJ94040.1 - 2.7e-05 24.2 0.3 9.7e-05 22.4 0.3 1.9 1 0 0 1 1 1 1 AAA lid domain ATPase_2 PF01637.18 CDJ94040.1 - 0.00019 21.5 0.1 0.00051 20.0 0.1 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 CDJ94040.1 - 0.0011 18.3 0.4 0.23 10.6 0.0 2.4 1 1 1 2 2 2 2 KAP family P-loop domain AAA_11 PF13086.6 CDJ94040.1 - 0.002 18.0 0.8 0.0048 16.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 CDJ94040.1 - 0.005 16.9 0.1 0.028 14.4 0.1 2.0 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit TIP49 PF06068.13 CDJ94040.1 - 0.0084 15.4 0.3 0.12 11.5 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain NB-ARC PF00931.22 CDJ94040.1 - 0.021 14.0 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ORC4_C PF14629.6 CDJ94040.1 - 0.021 14.2 0.1 0.046 13.1 0.1 1.5 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus AAA_18 PF13238.6 CDJ94040.1 - 0.034 14.7 0.0 0.11 13.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 CDJ94040.1 - 0.045 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CDJ94040.1 - 0.052 12.6 0.0 0.12 11.4 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF1045 PF06299.12 CDJ94040.1 - 0.062 13.3 0.5 0.18 11.8 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) MeaB PF03308.16 CDJ94040.1 - 0.088 11.8 0.5 0.16 10.9 0.1 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_32 PF13654.6 CDJ94040.1 - 0.09 11.5 0.2 0.23 10.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain RVT_1 PF00078.27 CDJ94041.1 - 7.3e-31 107.4 0.0 1.3e-30 106.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDJ94041.1 - 0.00085 19.3 0.0 0.0024 17.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DFRP_C PF16543.5 CDJ94041.1 - 0.1 13.1 0.4 0.27 11.7 0.4 1.6 1 0 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 Pkinase PF00069.25 CDJ94042.1 - 3.5e-26 92.2 0.0 4.2e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ94042.1 - 1.4e-13 50.7 0.1 1.7e-13 50.5 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ94042.1 - 0.00012 22.1 0.1 0.00055 19.9 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 CDJ94042.1 - 0.0016 18.1 0.0 0.19 11.3 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CDJ94042.1 - 0.0026 17.1 0.1 0.0044 16.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 CDJ94042.1 - 0.077 12.6 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 C6 PF01681.17 CDJ94043.1 - 1.3e-15 57.6 3.3 1.3e-07 32.0 0.7 2.2 2 0 0 2 2 2 2 C6 domain DUF5633 PF18656.1 CDJ94043.1 - 0.033 14.1 0.5 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5633) MAAL_C PF07476.11 CDJ94043.1 - 0.036 13.2 1.1 0.19 10.8 0.1 2.0 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus Rol_Rep_N PF18106.1 CDJ94043.1 - 0.04 14.2 0.0 4.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Rolling Circle replication initiation protein N-terminal domain LYTB PF02401.18 CDJ94043.1 - 0.096 11.9 0.6 2.3 7.4 0.2 2.1 1 1 1 2 2 2 0 LytB protein DUF281 PF03436.13 CDJ94043.1 - 0.11 12.9 10.9 3.2 8.2 0.0 4.9 6 0 0 6 6 6 0 Domain of unknown function (DUF281) CW_binding_1 PF01473.20 CDJ94043.1 - 0.27 11.6 2.9 6.6 7.3 0.3 2.5 2 0 0 2 2 2 0 Putative cell wall binding repeat DUF3715 PF12509.8 CDJ94044.1 - 1.3e-09 38.2 0.0 2.7e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3715) PPI_Ypi1 PF07491.11 CDJ94044.1 - 0.0075 16.1 0.1 0.022 14.6 0.1 1.8 1 0 0 1 1 1 1 Protein phosphatase inhibitor Tudor_3 PF18115.1 CDJ94044.1 - 0.049 13.5 0.0 0.49 10.3 0.0 2.6 3 0 0 3 3 3 0 DNA repair protein Crb2 Tudor domain G-patch PF01585.23 CDJ94045.1 - 8.2e-11 41.6 0.6 3.4e-10 39.6 0.6 2.1 2 0 0 2 2 2 1 G-patch domain RRM_1 PF00076.22 CDJ94045.1 - 4.4e-06 26.4 0.1 8.2e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pex2_Pex12 PF04757.14 CDJ94046.1 - 1.7e-12 47.4 1.2 4.3e-12 46.1 1.2 1.6 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_6 PF14835.6 CDJ94046.1 - 0.0015 18.4 0.5 0.003 17.4 0.5 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 CDJ94046.1 - 0.023 14.6 0.6 0.043 13.7 0.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ94046.1 - 0.031 14.1 0.9 0.062 13.1 0.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ94046.1 - 0.067 13.2 0.6 0.16 12.1 0.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Acyltransferase PF01553.21 CDJ94047.1 - 9.2e-31 106.2 0.0 1.4e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase NOA36 PF06524.12 CDJ94048.1 - 2.3e-125 418.0 66.5 6.8e-125 416.4 66.5 1.6 1 1 0 1 1 1 1 NOA36 protein Peptidase_M1 PF01433.20 CDJ94049.1 - 1.2e-54 185.2 0.0 2e-54 184.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CDJ94049.1 - 1.3e-33 116.8 0.0 2.2e-33 116.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 CDJ94049.1 - 2.1e-05 24.2 0.8 4.6e-05 23.1 0.8 1.6 1 0 0 1 1 1 1 ERAP1-like C-terminal domain DUF1907 PF08925.11 CDJ94050.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1907) Asp PF00026.23 CDJ94051.1 - 2.7e-35 122.3 1.3 3.3e-35 122.0 1.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ94051.1 - 3.8e-13 50.1 0.2 9.3e-08 32.5 0.3 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp PF00026.23 CDJ94052.1 - 1.5e-41 142.9 0.7 1.7e-41 142.7 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ94052.1 - 2.4e-12 47.5 0.1 1.3e-07 32.0 0.2 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TTR-52 PF01060.23 CDJ94053.1 - 4.1e-23 81.9 0.1 5.9e-23 81.4 0.1 1.2 1 0 0 1 1 1 1 Transthyretin-like family YAF2_RYBP PF17219.3 CDJ94053.1 - 0.019 14.6 0.2 0.045 13.3 0.2 1.6 1 0 0 1 1 1 0 Yaf2/RYBP C-terminal binding motif Sh_2 PF17512.2 CDJ94053.1 - 0.022 14.5 0.8 0.023 14.5 0.1 1.4 2 0 0 2 2 2 0 Metapneumovirus Small hydrophobic protein Sacchrp_dh_C PF16653.5 CDJ94054.1 - 4e-83 279.6 0.0 7.7e-83 278.6 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 CDJ94054.1 - 4.4e-28 98.3 0.0 3.2e-27 95.5 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 CDJ94054.1 - 7e-26 91.0 0.0 1.5e-25 90.0 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 CDJ94054.1 - 2.6e-06 26.9 0.0 0.0013 18.1 0.0 3.2 2 1 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain LRR_4 PF12799.7 CDJ94055.1 - 3e-16 59.3 1.7 3.5e-06 27.3 0.2 3.8 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ94055.1 - 2.9e-15 55.8 1.1 1.4e-08 34.3 0.2 2.5 2 1 1 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 CDJ94055.1 - 0.00018 21.3 5.2 0.046 13.8 0.2 4.2 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 CDJ94055.1 - 0.00084 19.6 3.2 52 5.0 0.1 5.3 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_9 PF14580.6 CDJ94055.1 - 0.0094 15.5 0.1 0.014 14.9 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat DNA_methylase PF00145.17 CDJ94056.1 - 1e-36 127.0 0.0 4.2e-36 125.0 0.0 1.7 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Membralin PF09746.9 CDJ94056.1 - 0.048 12.7 0.0 0.06 12.4 0.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein Neur_chan_LBD PF02931.23 CDJ94058.1 - 1.9e-38 132.1 1.1 2e-38 132.0 1.1 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ94059.1 - 5.8e-30 105.1 0.2 7e-30 104.8 0.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CDJ94059.1 - 5.5e-07 29.3 0.0 8.3e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain PalH PF08733.10 CDJ94059.1 - 2.4 7.1 6.2 1.2e+02 1.5 6.2 2.1 1 1 0 1 1 1 0 PalH/RIM21 Bromodomain PF00439.25 CDJ94061.1 - 2.2e-18 66.1 0.0 4.4e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain DUF883 PF05957.13 CDJ94063.1 - 0.014 15.9 3.1 1 10.0 0.2 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF3146 PF11344.8 CDJ94063.1 - 0.032 13.9 0.1 3.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3146) DUF4404 PF14357.6 CDJ94063.1 - 0.44 11.2 4.3 3 8.5 0.5 3.3 1 1 3 4 4 4 0 Domain of unknown function (DUF4404) DUF2164 PF09932.9 CDJ94063.1 - 0.49 10.5 3.3 2.1 8.5 0.1 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2164) Peptidase_C1 PF00112.23 CDJ94067.1 - 3.4e-47 161.3 13.4 4.9e-47 160.8 13.4 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ94067.1 - 0.00027 19.9 1.4 0.00027 19.9 1.4 1.8 2 0 0 2 2 2 1 Peptidase C1-like family DUF3724 PF12521.8 CDJ94067.1 - 0.089 12.7 0.7 0.23 11.4 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) IRF-2BP1_2 PF11261.8 CDJ94068.1 - 5.2e-32 109.2 4.7 5.2e-32 109.2 4.7 1.9 2 0 0 2 2 2 1 Interferon regulatory factor 2-binding protein zinc finger zf-C3HC4 PF00097.25 CDJ94068.1 - 0.065 13.1 10.7 0.2 11.6 10.7 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zip PF02535.22 CDJ94069.1 - 4.7e-42 144.4 20.3 1e-32 113.7 7.8 2.9 2 1 1 3 3 3 3 ZIP Zinc transporter SRPRB PF09439.10 CDJ94070.1 - 1.2e-50 171.4 0.0 1.6e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 CDJ94070.1 - 2.2e-12 46.8 0.0 4.6e-12 45.7 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ94070.1 - 2.2e-08 34.1 0.0 3.8e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CDJ94070.1 - 0.00013 22.1 0.0 0.00024 21.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 CDJ94070.1 - 0.00046 19.8 0.0 0.00077 19.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 CDJ94070.1 - 0.0014 18.0 0.0 0.0018 17.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 CDJ94070.1 - 0.066 13.0 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Xrn1_D3 PF18194.1 CDJ94070.1 - 0.2 11.8 1.0 0.3 11.2 0.1 1.8 2 0 0 2 2 2 0 Exoribonuclease 1 Domain-3 HTH_26 PF13443.6 CDJ94071.1 - 0.0023 18.3 0.1 0.0046 17.4 0.1 1.5 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_IclR PF09339.10 CDJ94071.1 - 0.007 16.1 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain DUF3602 PF12223.8 CDJ94071.1 - 0.012 16.2 0.5 0.028 15.0 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) DUF4572 PF15139.6 CDJ94071.1 - 0.024 14.6 0.1 0.042 13.8 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4572) HTH_24 PF13412.6 CDJ94071.1 - 0.04 13.5 0.0 0.087 12.4 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Collagen PF01391.18 CDJ94072.1 - 2.5e-26 91.2 110.0 2.4e-10 40.0 39.5 4.0 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ94072.1 - 5.9e-17 61.5 0.6 7.8e-17 61.1 0.6 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Hormone_recep PF00104.30 CDJ94073.1 - 1.6e-29 102.9 0.9 2.1e-29 102.6 0.9 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Med26 PF08711.11 CDJ94074.1 - 9.7e-13 47.9 0.0 2.1e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Acyl-CoA_ox_N PF14749.6 CDJ94074.1 - 0.048 14.2 0.1 0.048 14.2 0.1 1.7 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal LSDAT_euk PF18139.1 CDJ94076.1 - 2.2e-108 361.7 0.0 3e-108 361.3 0.0 1.2 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 CDJ94076.1 - 1.7e-18 66.6 0.0 2.9e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Ctr PF04145.15 CDJ94076.1 - 0.0052 17.4 0.1 0.021 15.5 0.1 2.0 1 1 0 1 1 1 1 Ctr copper transporter family CDC45 PF02724.14 CDJ94076.1 - 0.034 12.5 2.9 0.061 11.6 2.9 1.3 1 0 0 1 1 1 0 CDC45-like protein HGTP_anticodon2 PF12745.7 CDJ94076.1 - 0.2 11.1 4.3 0.35 10.3 4.3 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs RAP1 PF07218.11 CDJ94076.1 - 0.4 8.9 3.2 0.59 8.3 3.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.9 CDJ94076.1 - 0.87 9.2 18.6 0.041 13.5 12.5 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Fibrinogen_C PF00147.18 CDJ94077.1 - 2.4e-48 164.9 9.6 3.8e-48 164.2 9.6 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Lectin_C PF00059.21 CDJ94077.1 - 2.5e-10 41.0 6.7 2.5e-10 41.0 6.7 3.0 2 1 0 2 2 2 1 Lectin C-type domain Fibrinogen_C PF00147.18 CDJ94078.1 - 2.5e-48 164.8 9.4 4e-48 164.1 9.4 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Lectin_C PF00059.21 CDJ94078.1 - 2.5e-10 41.0 6.7 2.5e-10 41.0 6.7 3.0 2 1 0 2 2 2 1 Lectin C-type domain RVT_1 PF00078.27 CDJ94079.1 - 3.4e-38 131.4 0.0 6.6e-38 130.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDJ94079.1 - 0.00016 21.5 0.4 0.00047 20.0 0.0 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ94079.1 - 0.011 15.2 0.1 0.046 13.2 0.0 2.0 2 0 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family ERp29 PF07749.12 CDJ94079.1 - 0.33 11.9 2.0 32 5.5 0.1 2.5 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain Atg14 PF10186.9 CDJ94079.1 - 5.7 5.9 6.4 9.7 5.2 6.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cys_Met_Meta_PP PF01053.20 CDJ94082.1 - 6.7e-124 413.3 0.0 8e-124 413.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 CDJ94082.1 - 1.2e-06 27.3 0.0 1.9e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 CDJ94082.1 - 0.0035 16.4 0.0 0.0057 15.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V NHL PF01436.21 CDJ94083.1 - 4.6e-47 155.7 19.7 4e-11 42.4 0.3 5.5 5 0 0 5 5 5 5 NHL repeat SGL PF08450.12 CDJ94083.1 - 9.9e-06 25.3 0.0 0.88 9.1 0.0 3.7 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region DUF5128 PF17170.4 CDJ94083.1 - 1.6e-05 24.3 3.0 0.18 11.0 0.0 3.2 2 1 1 4 4 4 2 6-bladed beta-propeller SdiA-regulated PF06977.11 CDJ94083.1 - 0.097 11.9 0.0 0.78 8.9 0.0 2.4 2 1 2 4 4 4 0 SdiA-regulated Phytase-like PF13449.6 CDJ94083.1 - 0.21 11.5 0.0 27 4.6 0.0 3.0 2 1 2 4 4 4 0 Esterase-like activity of phytase potato_inhibit PF00280.18 CDJ94083.1 - 0.47 11.2 5.1 21 5.9 0.1 4.2 5 0 0 5 5 5 0 Potato inhibitor I family SCVP PF17619.2 CDJ94084.1 - 1.3e-22 80.5 0.0 1.5e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Secreted clade V proteins ChAPs PF09295.10 CDJ94084.1 - 0.081 11.9 0.0 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) Peptidase_S28 PF05577.12 CDJ94085.1 - 2.7e-08 33.1 0.0 3.1e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Lectin_C PF00059.21 CDJ94086.1 - 2.1e-15 57.4 1.0 4e-15 56.5 1.0 1.4 1 0 0 1 1 1 1 Lectin C-type domain Mucin PF01456.17 CDJ94087.1 - 0.45 10.5 27.6 0.66 10.0 27.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Mito_fiss_reg PF05308.11 CDJ94087.1 - 1.1 9.3 12.1 1.4 8.9 12.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator MGC-24 PF05283.11 CDJ94087.1 - 9.2 6.7 13.2 12 6.3 13.2 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TFIID_20kDa PF03847.13 CDJ94088.1 - 6.6e-18 65.0 1.9 9.5e-18 64.5 1.9 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIIA PF03153.13 CDJ94088.1 - 5.7 6.8 11.6 8.5 6.3 11.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribonuc_L-PSP PF01042.21 CDJ94089.1 - 1.2e-41 141.5 0.1 1.6e-41 141.1 0.1 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP CHIPS PF11434.8 CDJ94089.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS Troponin PF00992.20 CDJ94090.1 - 1.5e-43 148.3 18.6 1.5e-43 148.3 18.6 3.0 3 1 0 3 3 3 2 Troponin RTC4 PF14474.6 CDJ94090.1 - 2.4 8.3 6.2 0.64 10.2 0.7 2.2 2 0 0 2 2 2 0 RTC4-like domain DUF4615 PF15393.6 CDJ94091.1 - 0.052 14.1 1.3 0.094 13.3 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) FidL_like PF15941.5 CDJ94091.1 - 0.097 13.1 0.1 0.26 11.8 0.1 1.7 1 0 0 1 1 1 0 FidL-like putative membrane protein ISG65-75 PF11727.8 CDJ94091.1 - 0.15 11.2 4.5 0.24 10.6 4.5 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein zf-C2H2 PF00096.26 CDJ94094.1 - 0.00078 19.8 6.9 0.0014 19.0 2.3 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CDJ94094.1 - 0.035 14.4 9.8 0.064 13.6 1.5 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CDJ94094.1 - 0.075 13.9 1.7 0.075 13.9 1.7 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDJ94094.1 - 0.12 12.8 9.0 5.4 7.6 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain CEBP_ZZ PF16366.5 CDJ94094.1 - 0.83 9.9 12.0 0.57 10.5 10.5 1.6 1 1 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain RNA_pol_I_A49 PF06870.12 CDJ94095.1 - 0.13 11.1 0.0 0.75 8.6 0.0 2.0 2 0 0 2 2 2 0 A49-like RNA polymerase I associated factor Ins_beta PF03488.14 CDJ94100.1 - 0.12 12.4 19.8 0.17 11.9 14.7 2.6 2 1 0 2 2 2 0 Nematode insulin-related peptide beta type CHD5 PF04420.14 CDJ94101.1 - 7.6e-08 32.4 1.2 9.5e-08 32.1 0.1 1.8 2 0 0 2 2 2 1 CHD5-like protein Myb_DNA-binding PF00249.31 CDJ94101.1 - 6.8e-05 23.0 2.6 0.032 14.4 0.1 3.7 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ94101.1 - 0.14 12.4 3.8 0.58 10.5 0.0 3.3 3 0 0 3 3 3 0 Myb-like DNA-binding domain Globin PF00042.22 CDJ94102.1 - 8.7e-24 84.2 0.1 1.3e-23 83.6 0.1 1.3 1 0 0 1 1 1 1 Globin Vel1p PF10339.9 CDJ94102.1 - 0.082 12.3 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Yeast-specific zinc responsive Collar PF07484.12 CDJ94102.1 - 0.087 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Phage Tail Collar Domain Globin PF00042.22 CDJ94103.1 - 2.1e-23 83.0 0.1 3.2e-23 82.4 0.1 1.3 1 0 0 1 1 1 1 Globin Collar PF07484.12 CDJ94103.1 - 0.085 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Collar Domain Vel1p PF10339.9 CDJ94103.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Yeast-specific zinc responsive Trypsin PF00089.26 CDJ94104.1 - 2.2e-16 60.4 0.0 7.9e-16 58.5 0.0 1.7 1 1 0 1 1 1 1 Trypsin DUF316 PF03761.15 CDJ94104.1 - 1.2e-08 34.9 0.0 4.8e-07 29.6 0.0 2.6 1 1 0 1 1 1 1 Chymotrypsin family Peptidase-S1 Globin PF00042.22 CDJ94105.1 - 3.5e-43 146.6 2.6 1.5e-21 77.0 0.4 2.6 2 1 0 2 2 2 2 Globin Tex_N PF09371.10 CDJ94105.1 - 3.6e-06 26.8 0.1 0.074 12.7 0.0 2.4 2 1 0 2 2 2 2 Tex-like protein N-terminal domain TetR_C_15 PF17918.1 CDJ94105.1 - 0.013 16.3 2.2 0.22 12.3 0.1 3.1 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Glyco_transf_21 PF13506.6 CDJ94105.1 - 0.028 13.9 0.2 0.87 9.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 21 YchF-GTPase_C PF06071.13 CDJ94105.1 - 0.048 13.9 0.7 6.4 7.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF933) GDI PF00996.18 CDJ94105.1 - 0.066 11.7 1.2 1.1 7.7 0.1 2.0 2 0 0 2 2 2 0 GDP dissociation inhibitor ox_reductase_C PF08635.10 CDJ94105.1 - 0.11 12.1 0.0 8.3 6.1 0.0 2.2 2 0 0 2 2 2 0 Putative oxidoreductase C terminal domain Globin PF00042.22 CDJ94106.1 - 0.0025 18.3 0.0 0.0042 17.6 0.0 1.4 1 0 0 1 1 1 1 Globin Globin PF00042.22 CDJ94107.1 - 2.2e-12 47.5 0.0 2.6e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Globin Glyco_tran_WecB PF03808.13 CDJ94107.1 - 0.18 11.7 0.0 0.2 11.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Globin PF00042.22 CDJ94108.1 - 1.6e-08 35.1 0.0 4.8e-08 33.5 0.0 1.8 1 1 1 2 2 2 1 Globin Globin PF00042.22 CDJ94109.1 - 2.7e-25 89.1 0.4 2.7e-25 89.1 0.4 1.5 2 0 0 2 2 2 1 Globin Globin PF00042.22 CDJ94110.1 - 5.2e-24 84.9 0.3 8.9e-24 84.2 0.3 1.4 1 0 0 1 1 1 1 Globin Globin PF00042.22 CDJ94111.1 - 1.6e-23 83.4 0.3 2.7e-23 82.6 0.3 1.4 1 0 0 1 1 1 1 Globin DUF3847 PF12958.7 CDJ94112.1 - 0.0023 18.0 0.6 0.0039 17.3 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3847) DUF4407 PF14362.6 CDJ94112.1 - 0.087 12.2 2.0 0.096 12.0 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Globin PF00042.22 CDJ94113.1 - 1.2e-19 70.9 0.0 1.7e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Globin Acyltransf_C PF16076.5 CDJ94113.1 - 0.012 15.7 0.1 0.039 14.1 0.0 1.9 2 1 0 2 2 2 0 Acyltransferase C-terminus Tyrosinase PF00264.20 CDJ94114.1 - 5.4e-13 49.7 0.0 8.4e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase UDPGT PF00201.18 CDJ94115.1 - 2.3e-68 231.2 0.7 2.8e-68 230.9 0.7 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ94115.1 - 1.1e-07 32.0 0.0 2.1e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_4_2 PF13477.6 CDJ94115.1 - 0.0039 17.2 0.1 0.024 14.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like DUF5010 PF16402.5 CDJ94115.1 - 0.025 13.4 0.1 0.17 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5010) Glyco_transf_4 PF13439.6 CDJ94115.1 - 0.1 12.6 0.0 0.42 10.6 0.0 2.1 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 CDJ94115.1 - 0.19 12.2 0.0 2.9 8.3 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain DUF4440 PF14534.6 CDJ94116.1 - 7.9e-09 35.9 0.0 9.6e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 CDJ94116.1 - 0.00012 22.4 0.0 0.00014 22.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.20 CDJ94116.1 - 0.00087 19.9 0.0 0.00094 19.7 0.0 1.3 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_2 PF12680.7 CDJ94116.1 - 0.0061 17.2 0.1 0.0079 16.8 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain DHFR_1 PF00186.19 CDJ94116.1 - 0.1 12.3 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Dihydrofolate reductase Cnd1 PF12717.7 CDJ94117.1 - 0.021 14.9 0.1 0.03 14.4 0.1 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 MRC1 PF09444.10 CDJ94117.1 - 0.095 13.2 0.8 0.13 12.8 0.5 1.4 1 1 0 1 1 1 0 MRC1-like domain Mac PF12464.8 CDJ94117.1 - 0.096 12.9 0.2 0.34 11.2 0.0 1.9 2 0 0 2 2 2 0 Maltose acetyltransferase Siah-Interact_N PF09032.11 CDJ94117.1 - 0.12 12.7 0.1 2.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Siah interacting protein, N terminal FliT PF05400.13 CDJ94117.1 - 0.42 11.4 2.7 3 8.7 2.4 2.0 1 1 1 2 2 2 0 Flagellar protein FliT 7tm_1 PF00001.21 CDJ94118.1 - 2.1e-11 43.7 15.1 3.1e-11 43.1 15.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDJ94118.1 - 2.5e-11 43.5 13.3 3.3e-11 43.1 13.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw ECSCR PF15820.5 CDJ94118.1 - 0.14 12.0 0.1 0.14 12.0 0.1 2.5 3 0 0 3 3 3 0 Endothelial cell-specific chemotaxis regulator DUF4271 PF14093.6 CDJ94118.1 - 0.58 10.0 8.9 0.68 9.8 0.9 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4271) TMEM65 PF10507.9 CDJ94119.1 - 1.5e-22 79.6 1.7 2.7e-22 78.8 1.7 1.4 1 0 0 1 1 1 1 Transmembrane protein 65 Pan3_PK PF18101.1 CDJ94120.1 - 3e-62 208.7 0.0 4.6e-62 208.0 0.0 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain MOR2-PAG1_C PF14225.6 CDJ94120.1 - 0.052 13.4 0.1 0.091 12.6 0.1 1.3 1 0 0 1 1 1 0 Cell morphogenesis C-terminal Calreticulin PF00262.18 CDJ94121.1 - 1.6e-154 514.2 6.5 2.7e-154 513.5 6.5 1.3 1 0 0 1 1 1 1 Calreticulin family UPF0542 PF15086.6 CDJ94121.1 - 0.15 12.0 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 CX PF01705.19 CDJ94122.1 - 1.6e-11 44.6 3.2 7.9e-08 32.7 0.4 2.6 2 0 0 2 2 2 2 CX module Shisa PF13908.6 CDJ94122.1 - 0.0046 17.2 0.3 0.0046 17.2 0.3 3.0 1 1 2 3 3 3 1 Wnt and FGF inhibitory regulator TraT PF05818.12 CDJ94122.1 - 6.2 6.4 6.4 0.55 9.9 0.5 2.0 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein DUF4187 PF13821.6 CDJ94124.1 - 2.1e-15 56.2 5.0 5e-15 55.0 5.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 CDJ94124.1 - 1.5e-10 40.8 0.1 3.3e-10 39.7 0.1 1.6 1 1 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CDJ94124.1 - 7.2e-06 26.0 0.1 2.1e-05 24.5 0.1 1.8 1 0 0 1 1 1 1 G-patch domain FAM167 PF11652.8 CDJ94124.1 - 2.1 8.9 5.9 0.87 10.1 2.6 1.9 2 0 0 2 2 2 0 FAM167 Btz PF09405.10 CDJ94125.1 - 1.1e-06 29.0 5.7 2.1e-06 28.0 5.2 1.9 1 1 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding ERAP1_C PF11838.8 CDJ94126.1 - 3.6e-36 125.3 0.2 4.2e-36 125.1 0.2 1.0 1 0 0 1 1 1 1 ERAP1-like C-terminal domain LuxQ-periplasm PF09308.10 CDJ94126.1 - 0.00036 20.1 2.3 0.00059 19.4 2.3 1.2 1 0 0 1 1 1 1 LuxQ, periplasmic ATR13 PF16829.5 CDJ94126.1 - 0.095 13.1 0.4 0.48 10.8 0.1 2.2 1 1 0 2 2 2 0 Avirulence protein ATR13, RxLR effector DUF1129 PF06570.11 CDJ94127.1 - 0.11 12.0 4.6 0.18 11.3 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF502 PF04367.13 CDJ94127.1 - 0.13 12.1 0.5 0.29 11.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF502) Fig1 PF12351.8 CDJ94127.1 - 0.89 9.5 6.1 0.27 11.1 2.8 1.8 1 1 1 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Phage_holin_3_6 PF07332.11 CDJ94127.1 - 2.9 7.9 7.9 0.1 12.6 1.5 1.7 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III SPC12 PF06645.13 CDJ94127.1 - 3 8.0 6.2 12 6.1 2.1 2.4 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF2206 PF09971.9 CDJ94127.1 - 4.6 5.9 10.0 6.2 5.5 10.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) EMP24_GP25L PF01105.24 CDJ94128.1 - 2.3e-12 47.3 0.0 2.6e-12 47.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Cation_efflux PF01545.21 CDJ94129.1 - 9.8e-50 169.1 11.5 9.8e-50 169.1 11.5 2.9 2 1 0 2 2 2 1 Cation efflux family PRKCSH PF07915.13 CDJ94130.1 - 2.4e-27 95.7 12.7 2.6e-16 60.4 0.7 3.7 3 1 0 3 3 3 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 CDJ94130.1 - 2.1e-10 40.5 4.9 0.00014 21.6 1.4 2.5 2 1 0 2 2 2 2 Glucosidase II beta subunit-like protein DUF4417 PF14386.6 CDJ94130.1 - 0.05 13.2 0.0 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4417) KOW PF00467.29 CDJ94131.1 - 3.4e-08 33.2 0.7 7.5e-08 32.1 0.7 1.6 1 0 0 1 1 1 1 KOW motif ribosomal_L24 PF17136.4 CDJ94131.1 - 0.0002 21.7 0.0 0.0004 20.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 Zip PF02535.22 CDJ94132.1 - 1.7e-30 106.4 4.8 2.3e-30 105.9 4.8 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Cation_efflux PF01545.21 CDJ94132.1 - 0.69 9.6 7.9 0.25 11.0 0.7 2.9 2 1 1 3 3 3 0 Cation efflux family Tim17 PF02466.19 CDJ94132.1 - 2.6 8.5 5.5 1.7 9.0 0.1 3.0 2 1 1 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family DUF2981 PF11200.8 CDJ94133.1 - 0.022 14.5 2.4 0.025 14.3 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Phage_Gp23 PF10669.9 CDJ94133.1 - 0.038 14.3 0.0 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF2371 PF10177.9 CDJ94133.1 - 0.074 13.2 0.1 0.11 12.6 0.1 1.6 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) FSA_C PF10479.9 CDJ94133.1 - 5.6 5.0 13.8 7 4.6 13.8 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Exo_endo_phos PF03372.23 CDJ94134.1 - 0.17 11.4 0.0 0.66 9.4 0.0 1.8 1 1 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CDJ94134.1 - 0.18 11.6 0.0 0.92 9.4 0.0 1.9 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase RVT_1 PF00078.27 CDJ94135.1 - 8.4e-17 61.4 0.0 1.1e-16 61.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Methyltrn_RNA_3 PF02598.17 CDJ94136.1 - 0.1 12.1 0.3 0.15 11.6 0.0 1.4 2 0 0 2 2 2 0 Putative RNA methyltransferase Trehalase PF01204.18 CDJ94140.1 - 4.1e-94 316.2 0.0 5.4e-92 309.3 0.0 2.0 1 1 1 2 2 2 2 Trehalase GDE_C PF06202.14 CDJ94140.1 - 0.00031 19.8 0.2 0.00065 18.7 0.2 1.5 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase G-alpha PF00503.20 CDJ94141.1 - 8.3e-27 94.3 0.2 1e-26 94.0 0.2 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDJ94141.1 - 3.1e-10 39.8 0.0 5.8e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Peptidase_M48 PF01435.18 CDJ94141.1 - 0.083 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M48 Clc-like PF07062.12 CDJ94142.1 - 6e-69 231.7 21.0 9.4e-51 172.3 4.4 2.1 2 0 0 2 2 2 2 Clc-like Claudin_2 PF13903.6 CDJ94142.1 - 3.6e-05 23.6 20.6 0.00036 20.3 5.2 2.4 2 1 0 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 CDJ94142.1 - 0.00027 20.9 29.2 0.0023 17.9 8.3 3.3 3 1 0 3 3 3 2 Tight junction protein, Claudin-like 7TM-7TMR_HD PF07698.11 CDJ94142.1 - 2.9 7.6 25.2 0.05 13.4 10.9 2.6 2 1 0 2 2 2 0 7TM receptor with intracellular HD hydrolase zf-C3Hc3H PF13891.6 CDJ94143.1 - 1.3e-07 31.8 8.9 2.8e-07 30.8 8.9 1.6 1 0 0 1 1 1 1 Potential DNA-binding domain MNNL PF07657.13 CDJ94143.1 - 0.49 10.5 5.2 0.96 9.5 5.2 1.5 1 0 0 1 1 1 0 N terminus of Notch ligand UTP15_C PF09384.10 CDJ94145.1 - 8.8e-25 87.1 0.9 1.3e-24 86.5 0.9 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 CDJ94145.1 - 6.6e-19 67.9 0.0 0.022 15.6 0.0 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ94145.1 - 1.5e-10 41.2 0.0 0.016 15.5 0.0 4.6 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CDJ94145.1 - 0.065 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Nup133 N terminal like ArAE_1_C PF11728.8 CDJ94145.1 - 0.12 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain HTH_48 PF17906.1 CDJ94146.1 - 4.7e-07 29.8 0.3 7.5e-07 29.2 0.3 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase GerE PF00196.19 CDJ94146.1 - 0.021 14.4 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_32 PF13565.6 CDJ94146.1 - 0.023 15.3 0.0 0.058 14.0 0.0 1.7 1 1 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 CDJ94146.1 - 0.031 14.5 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 Transposase HTH_24 PF13412.6 CDJ94146.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding ubiquitin PF00240.23 CDJ94147.1 - 4.6e-16 58.3 0.0 5.6e-16 58.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CDJ94147.1 - 0.00014 21.6 0.0 0.00015 21.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 CDJ94147.1 - 0.0061 16.5 0.0 0.0068 16.3 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CDJ94147.1 - 0.022 15.1 0.0 0.025 14.9 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_2 PF14560.6 CDJ94147.1 - 0.048 14.1 0.0 0.25 11.8 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain Med12-LCEWAV PF12145.8 CDJ94148.1 - 6.4e-36 124.2 4.4 6.4e-36 124.2 4.4 3.6 2 1 0 2 2 2 1 Eukaryotic Mediator 12 subunit domain Med12 PF09497.10 CDJ94148.1 - 3.9e-10 39.9 0.1 1.2e-09 38.4 0.1 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 EzrA PF06160.12 CDJ94149.1 - 0.00017 19.9 7.5 0.00017 19.9 7.5 1.6 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA Ribosomal_S2 PF00318.20 CDJ94149.1 - 0.023 13.9 3.2 0.021 14.0 1.5 1.9 1 1 1 2 2 2 0 Ribosomal protein S2 ZapB PF06005.12 CDJ94149.1 - 0.084 13.3 24.7 0.032 14.7 7.0 4.6 4 1 0 4 4 4 0 Cell division protein ZapB HALZ PF02183.18 CDJ94149.1 - 6.3 7.1 15.9 0.84 9.9 1.1 4.7 6 1 0 6 6 6 0 Homeobox associated leucine zipper DUF3450 PF11932.8 CDJ94149.1 - 9.7 5.4 17.7 0.53 9.5 9.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF5040 PF16443.5 CDJ94150.1 - 0.14 11.5 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5040) CD36 PF01130.21 CDJ94152.1 - 1.9e-108 363.0 0.5 2.2e-108 362.8 0.5 1.0 1 0 0 1 1 1 1 CD36 family DUF4405 PF14358.6 CDJ94152.1 - 0.0041 17.6 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4405) Saf_2TM PF18303.1 CDJ94152.1 - 0.012 15.2 0.2 0.14 11.7 0.0 2.2 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain PorA PF11271.8 CDJ94152.1 - 0.1 11.9 0.0 0.8 8.9 0.0 2.3 3 0 0 3 3 3 0 Porin PorA Serpin PF00079.20 CDJ94153.1 - 3.8e-39 135.1 0.1 4.1e-39 134.9 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) PyrBI_leader PF08052.11 CDJ94153.1 - 0.095 12.7 0.1 1.7 8.7 0.0 2.5 3 0 0 3 3 3 0 PyrBI operon leader peptide adh_short PF00106.25 CDJ94156.1 - 1.7e-29 102.7 0.0 2e-28 99.2 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ94156.1 - 4.3e-19 69.0 0.0 6.4e-18 65.2 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ94156.1 - 4.4e-05 23.5 0.1 8e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 KR domain Globin PF00042.22 CDJ94157.1 - 1.4e-06 28.8 0.0 2.7e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Globin Med2 PF11214.8 CDJ94157.1 - 0.09 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Mediator complex subunit 2 Tmemb_55A PF09788.9 CDJ94158.1 - 6.3e-07 28.7 2.6 7.6e-07 28.5 2.6 1.1 1 0 0 1 1 1 1 Transmembrane protein 55A Lar_restr_allev PF14354.6 CDJ94158.1 - 0.016 15.6 2.8 0.11 12.9 0.1 2.2 1 1 1 2 2 2 0 Restriction alleviation protein Lar TauE PF01925.19 CDJ94158.1 - 0.029 14.0 1.1 0.034 13.8 1.1 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE DUF2721 PF11026.8 CDJ94158.1 - 0.035 14.0 3.1 0.047 13.6 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Zn_Tnp_IS1595 PF12760.7 CDJ94158.1 - 0.13 12.3 8.9 0.95 9.5 1.1 2.6 1 1 1 2 2 2 0 Transposase zinc-ribbon domain YrhC PF14143.6 CDJ94158.1 - 0.3 11.2 6.5 0.84 9.8 6.5 1.7 1 1 0 1 1 1 0 YrhC-like protein zf-Di19 PF05605.12 CDJ94158.1 - 0.55 10.6 8.1 3.8 7.9 0.6 2.7 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF4131 PF13567.6 CDJ94158.1 - 1.2 8.8 4.6 1.6 8.3 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Zip PF02535.22 CDJ94161.1 - 9.3e-50 169.7 13.7 1.1e-27 97.1 3.2 3.1 2 1 1 3 3 3 3 ZIP Zinc transporter Asp PF00026.23 CDJ94162.1 - 9.1e-88 294.7 4.9 1.1e-87 294.4 4.9 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ94162.1 - 7.3e-12 45.9 5.1 5.4e-10 39.8 5.1 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CDJ94162.1 - 0.00077 20.1 0.2 0.93 10.2 0.0 3.1 3 0 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.6 CDJ94162.1 - 0.0024 17.7 0.0 0.017 14.9 0.0 2.2 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Myosin_TH1 PF06017.13 CDJ94163.1 - 0.017 14.8 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding Fer4_20 PF14691.6 CDJ94164.1 - 2.3e-33 114.4 0.6 4.2e-33 113.5 0.6 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 CDJ94164.1 - 3.1e-06 27.3 0.0 6.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CDJ94164.1 - 0.016 14.5 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_11 PF13247.6 CDJ94164.1 - 0.045 13.9 1.5 3.9 7.7 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain Pyr_redox_3 PF13738.6 CDJ94164.1 - 0.13 11.4 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CDJ94164.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 CDJ94164.1 - 0.21 10.8 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Fer4_10 PF13237.6 CDJ94164.1 - 3.5 7.8 11.9 1.4 9.0 7.9 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain Roc PF08477.13 CDJ94165.1 - 7.9e-16 58.4 0.1 8.8e-16 58.2 0.1 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDJ94165.1 - 1.7e-15 57.0 0.2 1.8e-15 56.9 0.2 1.0 1 0 0 1 1 1 1 Ras family AAA_7 PF12775.7 CDJ94165.1 - 0.00024 20.7 0.0 0.00025 20.6 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region Arf PF00025.21 CDJ94165.1 - 0.00035 20.1 0.2 0.00037 20.0 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ94165.1 - 0.00036 20.0 0.0 0.00039 19.9 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 CDJ94165.1 - 0.0007 20.0 0.0 0.0007 20.0 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 CDJ94165.1 - 0.00094 19.0 0.0 0.001 18.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 CDJ94165.1 - 0.0013 18.2 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial TniB protein AAA_22 PF13401.6 CDJ94165.1 - 0.0013 19.0 0.0 0.0013 19.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ94165.1 - 0.0018 18.6 0.0 0.0019 18.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CDJ94165.1 - 0.0023 18.4 0.0 0.0023 18.3 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDJ94165.1 - 0.0043 17.1 0.0 0.0043 17.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 CDJ94165.1 - 0.005 16.0 0.0 0.005 16.0 0.0 1.1 1 0 0 1 1 1 1 MCM P-loop domain MMR_HSR1 PF01926.23 CDJ94165.1 - 0.006 16.7 0.0 0.0067 16.5 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 CDJ94165.1 - 0.0085 15.9 0.0 0.009 15.8 0.0 1.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 CDJ94165.1 - 0.013 15.5 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 CDJ94165.1 - 0.014 14.7 0.0 0.014 14.7 0.0 1.0 1 0 0 1 1 1 0 Septin Sigma54_activat PF00158.26 CDJ94165.1 - 0.015 15.0 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.6 CDJ94165.1 - 0.018 14.8 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CDJ94165.1 - 0.02 15.5 0.0 0.02 15.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.6 CDJ94165.1 - 0.02 13.7 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 CDJ94165.1 - 0.021 13.9 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF2075 PF09848.9 CDJ94165.1 - 0.024 13.9 0.0 0.024 13.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.13 CDJ94165.1 - 0.037 13.2 0.0 0.037 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 CDJ94165.1 - 0.038 13.8 0.0 0.04 13.7 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 CDJ94165.1 - 0.041 13.6 0.0 0.041 13.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CDJ94165.1 - 0.045 13.1 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 KaiC Mg_chelatase PF01078.21 CDJ94165.1 - 0.046 13.1 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SRPRB PF09439.10 CDJ94165.1 - 0.06 12.8 0.0 0.063 12.7 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit UvrD-helicase PF00580.21 CDJ94165.1 - 0.081 12.4 0.0 0.098 12.2 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF4998 PF16389.5 CDJ94165.1 - 0.085 12.4 0.0 0.085 12.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function FeoB_N PF02421.18 CDJ94165.1 - 0.1 12.1 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Ferrous iron transport protein B RNA_helicase PF00910.22 CDJ94165.1 - 0.11 12.9 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 CDJ94165.1 - 0.11 12.7 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CDJ94165.1 - 0.12 12.6 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.25 CDJ94166.1 - 0.0029 17.8 0.0 0.0056 16.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CDJ94166.1 - 0.0044 17.0 0.0 0.009 16.0 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 CDJ94166.1 - 0.063 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short PF00106.25 CDJ94167.1 - 1.2e-07 31.4 0.9 6.4e-07 29.0 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ94167.1 - 2.1e-06 27.5 0.2 1e-05 25.2 0.0 1.9 1 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 CDJ94167.1 - 0.032 14.1 0.5 0.057 13.3 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PALP PF00291.25 CDJ94167.1 - 0.087 12.2 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme zf-CCCH PF00642.24 CDJ94168.1 - 0.00017 21.4 1.0 0.00017 21.4 1.0 2.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup160 PF11715.8 CDJ94169.1 - 8e-48 163.4 1.9 1.1e-47 162.9 1.9 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 GIY-YIG PF01541.24 CDJ94170.1 - 5.3e-14 52.3 0.0 9.8e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain PHD PF00628.29 CDJ94170.1 - 4.1e-05 23.4 5.2 9.5e-05 22.2 5.2 1.7 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 CDJ94170.1 - 4.2e-05 23.4 5.4 0.00056 19.8 3.2 2.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 C1_1 PF00130.22 CDJ94170.1 - 0.0012 18.7 8.0 0.0014 18.4 5.7 2.1 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.6 CDJ94170.1 - 0.0014 18.9 5.0 0.0036 17.6 5.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-PHD-like PF15446.6 CDJ94170.1 - 0.015 15.0 1.7 0.015 15.0 1.7 1.6 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain FANCL_C PF11793.8 CDJ94170.1 - 0.07 13.3 5.3 0.22 11.7 5.3 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_9 PF13901.6 CDJ94170.1 - 0.089 12.8 6.9 0.13 12.2 6.9 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-RING_11 PF17123.5 CDJ94170.1 - 0.41 10.4 2.8 0.93 9.3 2.8 1.7 1 0 0 1 1 1 0 RING-like zinc finger PHD_4 PF16866.5 CDJ94170.1 - 0.45 10.6 6.0 1.2 9.3 5.7 1.9 1 1 0 1 1 1 0 PHD-finger DZR PF12773.7 CDJ94170.1 - 5 7.2 9.9 1.2e+02 2.8 9.9 2.6 1 1 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 CDJ94170.1 - 9.5 6.2 9.7 0.2 11.6 2.9 1.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain RNA_pol_N PF01194.17 CDJ94171.1 - 2.5e-33 114.2 0.3 2.8e-33 114.0 0.3 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 CDJ94171.1 - 0.017 15.3 0.2 0.026 14.8 0.2 1.3 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) 4F5 PF04419.14 CDJ94172.1 - 2.8e-10 40.9 10.6 2.8e-10 40.9 10.6 2.8 2 1 0 2 2 2 1 4F5 protein family Calponin PF00402.18 CDJ94173.1 - 7.9e-11 41.4 0.4 1.3e-10 40.7 0.4 1.3 1 0 0 1 1 1 1 Calponin family repeat Astacin PF01400.24 CDJ94174.1 - 1.3e-67 227.1 0.0 2.7e-67 226.1 0.0 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB PF00431.20 CDJ94174.1 - 1.7e-07 31.5 0.0 3.6e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 CUB domain TSP_1 PF00090.19 CDJ94174.1 - 1.9e-05 24.7 13.5 5.6e-05 23.3 13.5 1.9 1 0 0 1 1 1 1 Thrombospondin type 1 domain p450 PF00067.22 CDJ94175.1 - 1e-07 31.1 0.1 1.2e-07 30.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 CDJ94176.1 - 1.6e-24 86.5 0.3 1.8e-24 86.3 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 MAP1B_neuraxin PF00414.17 CDJ94176.1 - 0.14 11.7 0.7 0.24 11.0 0.7 1.4 1 0 0 1 1 1 0 Neuraxin and MAP1B repeat Rad10 PF03834.14 CDJ94177.1 - 3.2e-38 130.3 0.1 4.5e-38 129.8 0.1 1.1 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_2 PF12826.7 CDJ94177.1 - 2.4e-06 27.5 0.0 4.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 CDJ94177.1 - 2e-05 25.1 0.0 3.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 CDJ94177.1 - 0.00046 19.9 0.0 0.00093 19.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_3 PF12836.7 CDJ94177.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif HTH_26 PF13443.6 CDJ94178.1 - 0.0021 18.5 0.0 0.0042 17.5 0.0 1.5 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_IclR PF09339.10 CDJ94178.1 - 0.007 16.1 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain DUF3602 PF12223.8 CDJ94178.1 - 0.012 16.2 0.5 0.028 15.0 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) HTH_24 PF13412.6 CDJ94178.1 - 0.041 13.4 0.0 0.087 12.4 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding EF-hand_1 PF00036.32 CDJ94179.1 - 2.8e-21 73.4 11.4 3.6e-07 29.3 0.3 4.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CDJ94179.1 - 8.3e-21 74.2 8.1 2e-13 50.5 0.2 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CDJ94179.1 - 2e-20 70.9 7.1 5.6e-06 25.9 0.2 4.6 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 CDJ94179.1 - 7.1e-13 48.2 7.0 1.7e-07 31.0 0.6 3.6 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ94179.1 - 1.4e-09 37.0 11.0 9.2e-05 21.8 0.3 4.0 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 CDJ94179.1 - 1e-07 31.9 3.3 0.073 13.0 0.0 3.5 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CDJ94179.1 - 0.00081 19.7 4.0 0.083 13.2 0.3 3.3 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CDJ94179.1 - 0.0049 17.2 0.0 0.026 14.9 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 CDJ94179.1 - 0.019 15.2 0.0 1.1 9.5 0.0 2.6 3 0 0 3 3 2 0 Dockerin type I domain Homeobox_KN PF05920.11 CDJ94179.1 - 0.045 13.7 0.4 0.098 12.6 0.4 1.5 1 0 0 1 1 1 0 Homeobox KN domain DUF5301 PF17225.3 CDJ94179.1 - 0.063 13.7 0.1 0.14 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5300) eIF3_N PF09440.10 CDJ94179.1 - 0.097 13.1 0.7 0.94 9.9 0.0 2.1 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain Caleosin PF05042.13 CDJ94179.1 - 1.8 8.5 5.1 47 3.9 0.0 3.5 3 1 1 4 4 4 0 Caleosin related protein WD40 PF00400.32 CDJ94180.1 - 7.9e-17 61.3 5.4 0.0028 18.5 1.2 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ94180.1 - 4.9e-05 23.6 0.3 0.019 15.2 0.1 4.1 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Y_phosphatase PF00102.27 CDJ94181.1 - 1.1e-61 208.4 0.0 5.2e-35 121.1 0.1 2.2 1 1 1 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ94181.1 - 0.00021 21.1 0.0 0.00051 19.9 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDJ94181.1 - 0.044 13.8 0.0 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family RRP7 PF12923.7 CDJ94182.1 - 1.3e-23 83.3 11.4 2.2e-23 82.7 11.4 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF3042 PF11240.8 CDJ94182.1 - 1.9 8.6 5.3 0.33 11.0 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) ParA PF10609.9 CDJ94183.1 - 1.8e-67 227.4 0.7 2e-67 227.2 0.7 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CDJ94183.1 - 1.4e-10 41.3 0.0 1.6e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CDJ94183.1 - 6.6e-08 32.7 0.1 8.7e-07 29.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 CDJ94183.1 - 5.1e-07 29.2 0.9 4.4e-06 26.1 0.4 2.2 1 1 1 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 CDJ94183.1 - 9.8e-05 21.8 0.0 0.00018 20.9 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.6 CDJ94183.1 - 0.00016 21.4 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ94183.1 - 0.00031 21.2 0.0 0.00044 20.7 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain CBP_BcsQ PF06564.12 CDJ94183.1 - 0.00095 18.7 0.0 0.0096 15.4 0.0 2.0 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 CDJ94183.1 - 0.0042 16.1 0.1 0.0066 15.5 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 CDJ94183.1 - 0.0054 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Fer4_NifH PF00142.18 CDJ94183.1 - 0.013 14.9 0.0 0.013 14.9 0.0 1.5 2 0 0 2 2 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Rad17 PF03215.15 CDJ94183.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Zeta_toxin PF06414.12 CDJ94183.1 - 0.019 14.3 0.0 0.019 14.3 0.0 1.9 3 0 0 3 3 2 0 Zeta toxin RNA_helicase PF00910.22 CDJ94183.1 - 0.02 15.3 0.0 0.036 14.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF87 PF01935.17 CDJ94183.1 - 0.02 15.0 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain APS_kinase PF01583.20 CDJ94183.1 - 0.039 13.8 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 CDJ94183.1 - 0.046 14.3 0.1 0.046 14.3 0.1 1.8 2 1 0 2 2 1 0 AAA domain SRP54 PF00448.22 CDJ94183.1 - 0.048 13.3 0.9 0.14 11.8 0.0 2.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 CDJ94183.1 - 0.051 13.3 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CDJ94183.1 - 0.064 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NinF PF05810.12 CDJ94183.1 - 0.065 13.1 0.8 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 NinF protein AAA_22 PF13401.6 CDJ94183.1 - 0.07 13.4 0.0 0.12 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CDJ94183.1 - 0.072 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 CDJ94183.1 - 0.079 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 CDJ94183.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 CDJ94183.1 - 0.1 11.6 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 CDJ94183.1 - 0.17 11.6 1.6 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain CLP1_P PF16575.5 CDJ94183.1 - 0.17 11.6 0.0 0.37 10.6 0.0 1.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop KTI12 PF08433.10 CDJ94183.1 - 0.18 11.2 0.0 0.23 10.9 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.6 CDJ94183.1 - 0.33 11.1 1.2 0.34 11.0 0.0 1.9 2 1 0 2 2 1 0 AAA domain zf-C4 PF00105.18 CDJ94184.1 - 7.6e-27 93.6 15.1 1.2e-26 93.0 15.1 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ94184.1 - 3e-09 36.7 2.2 2.1e-06 27.5 0.1 2.2 1 1 1 2 2 2 2 Ligand-binding domain of nuclear hormone receptor RVT_1 PF00078.27 CDJ94185.1 - 1.6e-10 40.9 0.0 4.7e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SpoIIAA-like PF11964.8 CDJ94186.1 - 0.041 14.9 0.2 0.066 14.3 0.2 1.4 1 1 0 1 1 1 0 SpoIIAA-like PTR2 PF00854.21 CDJ94187.1 - 8.9e-37 126.8 6.4 1.4e-36 126.2 6.4 1.3 1 0 0 1 1 1 1 POT family Mito_carr PF00153.27 CDJ94191.1 - 3.2e-54 180.8 1.8 1.2e-20 73.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 CDJ94191.1 - 0.078 13.4 1.2 2.2 8.7 0.1 2.6 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family COPIIcoated_ERV PF07970.12 CDJ94192.1 - 1.3e-26 93.8 0.1 2.1e-26 93.2 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CDJ94192.1 - 6.9e-14 52.0 0.5 1.4e-13 51.0 0.5 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ACP_syn_III_C PF08541.10 CDJ94192.1 - 0.14 12.3 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 7tm_2 PF00002.24 CDJ94193.1 - 4.3e-18 65.5 9.8 4.3e-18 65.5 9.8 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 CDJ94193.1 - 1.7e-08 34.7 5.3 4.4e-08 33.3 5.3 1.7 1 0 0 1 1 1 1 Hormone receptor domain DUF5513 PF17632.2 CDJ94193.1 - 0.043 14.2 0.9 0.18 12.3 0.0 2.3 2 1 1 3 3 3 0 Family of unknown function (DUF5513) TERF2_RBM PF16772.5 CDJ94194.1 - 0.098 12.1 0.3 0.18 11.2 0.3 1.4 1 0 0 1 1 1 0 Telomeric repeat-binding factor 2 Rap1-binding motif DUF1758 PF05585.12 CDJ94195.1 - 9.5e-09 35.2 0.1 2.5e-08 33.9 0.1 1.7 1 1 0 1 1 1 1 Putative peptidase (DUF1758) gag-asp_proteas PF13975.6 CDJ94195.1 - 0.0011 19.5 0.1 0.0032 18.0 0.1 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ94195.1 - 0.002 17.9 0.0 0.0041 16.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ94195.1 - 0.0041 17.7 0.1 0.013 16.1 0.1 1.8 2 0 0 2 2 2 1 Aspartyl protease DUF905 PF06006.12 CDJ94195.1 - 0.14 12.1 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) Mito_carr PF00153.27 CDJ94199.1 - 1.7e-49 165.7 3.3 3.1e-19 68.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein adh_short PF00106.25 CDJ94200.1 - 4.5e-47 160.0 2.4 6e-47 159.6 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ94200.1 - 1.5e-46 158.9 3.3 2e-46 158.5 3.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ94200.1 - 4.1e-07 30.1 0.2 7.5e-07 29.2 0.2 1.4 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 CDJ94200.1 - 7.7e-06 25.3 0.7 1.5e-05 24.4 0.7 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 CDJ94200.1 - 0.0029 17.1 2.4 0.021 14.3 2.4 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Dirigent PF03018.14 CDJ94200.1 - 0.0049 16.7 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 Dirigent-like protein 3HCDH_N PF02737.18 CDJ94200.1 - 0.0086 16.0 1.1 0.02 14.7 1.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh_N PF04455.12 CDJ94200.1 - 0.022 15.2 0.9 0.16 12.4 0.3 2.2 1 1 1 2 2 2 0 LOR/SDH bifunctional enzyme conserved region PALP PF00291.25 CDJ94200.1 - 0.039 13.4 1.2 0.16 11.4 0.3 1.9 1 1 1 2 2 2 0 Pyridoxal-phosphate dependent enzyme Ras PF00071.22 CDJ94201.1 - 6.7e-48 162.3 0.0 8.7e-48 162.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ94201.1 - 5.1e-31 107.4 0.0 8.6e-31 106.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ94201.1 - 1.5e-12 47.3 0.0 2.6e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ94201.1 - 3.6e-05 23.2 0.0 7.3e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CDJ94201.1 - 0.00083 18.9 0.2 0.0015 18.1 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CDJ94201.1 - 0.0016 18.8 0.0 0.0032 17.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 CDJ94201.1 - 0.002 18.2 0.0 0.0039 17.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CDJ94201.1 - 0.0024 17.3 0.0 0.004 16.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 CDJ94201.1 - 0.0095 15.9 0.0 0.14 12.0 0.0 2.4 2 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CDJ94201.1 - 0.032 14.5 0.2 0.77 10.0 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 CDJ94201.1 - 0.048 13.4 0.1 0.11 12.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain DUF4817 PF16087.5 CDJ94201.1 - 0.092 12.6 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) ATP_bind_1 PF03029.17 CDJ94201.1 - 0.15 11.8 0.7 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 CDJ94201.1 - 0.16 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Asp PF00026.23 CDJ94202.1 - 1.6e-99 333.3 0.0 1.9e-99 333.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ94202.1 - 1.1e-14 55.0 2.5 2.8e-13 50.5 1.8 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ94202.1 - 7.9e-06 25.7 0.0 3.7e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CDJ94202.1 - 0.00015 22.4 0.2 0.19 12.4 0.0 3.0 3 0 0 3 3 3 2 Aspartyl protease TMEM151 PF14857.6 CDJ94203.1 - 2.5e-128 428.7 0.6 3.5e-128 428.2 0.6 1.1 1 0 0 1 1 1 1 TMEM151 family PRIMA1 PF16101.5 CDJ94205.1 - 0.6 10.2 3.3 1.4 9.0 3.3 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 adh_short_C2 PF13561.6 CDJ94206.1 - 5.1e-22 78.6 0.0 6.2e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDJ94206.1 - 1.4e-10 40.9 0.0 2e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase RecO_N_2 PF13114.6 CDJ94206.1 - 0.033 13.9 0.0 0.32 10.7 0.0 2.3 2 0 0 2 2 2 0 RecO N terminal HHH_4 PF14490.6 CDJ94206.1 - 0.051 13.6 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix containing domain DOMON PF03351.17 CDJ94209.1 - 2.9e-06 27.5 0.1 8e-06 26.1 0.1 1.7 1 1 0 1 1 1 1 DOMON domain LIM PF00412.22 CDJ94210.1 - 3.2e-10 40.1 8.8 4.7e-10 39.6 8.8 1.2 1 0 0 1 1 1 1 LIM domain DUF2175 PF09943.9 CDJ94210.1 - 2.6 8.4 7.4 4.1 7.8 4.6 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) TAF6_C PF07571.13 CDJ94211.1 - 7.8e-13 48.6 0.0 2.9e-12 46.7 0.0 2.0 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 CDJ94211.1 - 8e-09 35.5 0.0 3.8e-08 33.4 0.0 2.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CDJ94211.1 - 0.057 13.7 0.5 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 CDJ94211.1 - 0.15 12.1 0.0 0.42 10.6 0.0 1.7 1 0 0 1 1 1 0 Bromodomain associated zf-U1 PF06220.12 CDJ94212.1 - 8.5e-07 28.6 0.0 1.6e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 U1 zinc finger WW PF00397.26 CDJ94212.1 - 5.5e-06 26.4 0.7 1.2e-05 25.2 0.7 1.6 1 0 0 1 1 1 1 WW domain DUF1612 PF07756.12 CDJ94212.1 - 0.0034 17.6 0.7 0.0077 16.5 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1612) MBDa PF16564.5 CDJ94212.1 - 0.025 14.7 0.4 0.093 12.9 0.4 2.0 1 0 0 1 1 1 0 p55-binding region of Methyl-CpG-binding domain proteins MBD PDDEXK_7 PF04411.12 CDJ94212.1 - 0.061 13.3 0.2 11 6.0 0.0 2.3 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily zf-C2H2_jaz PF12171.8 CDJ94212.1 - 0.12 12.7 3.0 0.38 11.1 1.4 2.7 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDJ94212.1 - 1.1 9.8 3.1 14 6.2 3.1 2.7 1 1 0 1 1 1 0 Zinc-finger of C2H2 type TFIID-18kDa PF02269.16 CDJ94213.1 - 1.3e-35 121.2 0.3 1.8e-35 120.9 0.3 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 CDJ94213.1 - 0.055 13.5 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated DUF4947 PF16305.5 CDJ94213.1 - 0.14 12.2 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4947) Pmp3 PF01679.17 CDJ94214.1 - 4.2e-29 100.5 32.4 5.8e-19 68.0 11.0 2.6 3 0 0 3 3 3 2 Proteolipid membrane potential modulator STAR_dimer PF16544.5 CDJ94214.1 - 0.13 11.8 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 Homodimerisation region of STAR domain protein zf-BED PF02892.15 CDJ94216.1 - 2e-14 53.3 11.1 3.3e-07 30.2 3.0 2.4 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_4 PF13894.6 CDJ94216.1 - 0.0043 17.8 15.8 0.16 12.9 2.0 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger FYVE PF01363.21 CDJ94216.1 - 0.026 14.7 6.1 0.15 12.2 1.4 2.5 2 0 0 2 2 2 0 FYVE zinc finger Zf_RING PF16744.5 CDJ94216.1 - 0.084 13.0 5.2 0.38 10.9 1.1 2.4 2 0 0 2 2 2 0 KIAA1045 RING finger DUF5617 PF18493.1 CDJ94216.1 - 0.09 12.9 0.4 2.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5617) zf-C2H2_12 PF18658.1 CDJ94216.1 - 0.22 11.1 3.6 3.4 7.3 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger C2H2-type AAA_13 PF13166.6 CDJ94216.1 - 0.23 10.1 3.3 0.35 9.4 3.3 1.2 1 0 0 1 1 1 0 AAA domain zf-Di19 PF05605.12 CDJ94216.1 - 0.28 11.5 6.4 8.3 6.8 0.2 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Plexin_cytopl PF08337.12 CDJ94218.1 - 8.8e-137 457.1 0.0 1.6e-136 456.3 0.0 1.3 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.24 CDJ94218.1 - 2.6e-31 107.5 10.1 2.4e-10 40.4 0.3 4.4 4 0 0 4 4 4 4 IPT/TIG domain Exo_endo_phos_2 PF14529.6 CDJ94220.1 - 1.6e-09 37.6 0.0 2.1e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ94220.1 - 2e-05 24.3 0.0 4.2e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CDJ94221.1 - 1.6e-09 37.6 0.0 2.1e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ94221.1 - 2e-05 24.3 0.0 4.2e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Flagellar_rod PF05149.12 CDJ94222.1 - 0.26 10.7 6.1 0.4 10.1 0.0 3.1 2 2 1 3 3 3 0 Paraflagellar rod protein RVT_1 PF00078.27 CDJ94223.1 - 9.2e-05 22.1 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tax PF02959.16 CDJ94223.1 - 0.15 11.5 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 HTLV Tax Exo_endo_phos_2 PF14529.6 CDJ94225.1 - 3.8e-05 23.5 0.1 0.00015 21.5 0.1 2.1 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ94225.1 - 0.01 15.4 0.1 0.044 13.3 0.0 1.9 2 0 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family AAA_lid_10 PF17872.1 CDJ94225.1 - 0.11 12.6 0.4 0.23 11.6 0.4 1.5 1 0 0 1 1 1 0 AAA lid domain RVT_1 PF00078.27 CDJ94225.1 - 0.15 11.6 0.0 0.33 10.4 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) CorA PF01544.18 CDJ94225.1 - 3 7.1 4.4 3.1 7.0 0.2 2.2 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Atg14 PF10186.9 CDJ94225.1 - 3.3 6.7 6.5 5.1 6.1 6.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Collagen PF01391.18 CDJ94226.1 - 4.4e-25 87.2 118.9 7.9e-11 41.6 41.4 4.0 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ94226.1 - 3e-20 72.0 1.0 4.2e-20 71.6 1.0 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain IBV_3B PF03622.13 CDJ94226.1 - 0.13 12.4 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 IBV 3B protein 7tm_1 PF00001.21 CDJ94227.1 - 1e-31 110.3 18.7 1.1e-31 110.1 18.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2116 PF09889.9 CDJ94227.1 - 0.21 11.6 2.4 13 5.8 0.4 2.6 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Exo_endo_phos_2 PF14529.6 CDJ94228.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase TGS PF02824.21 CDJ94230.1 - 1.3e-16 60.4 0.0 2e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 TGS domain SpoIISB_antitox PF14185.6 CDJ94230.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Antitoxin SpoIISB, type II toxin-antitoxin system tRNA-synt_2b PF00587.25 CDJ94231.1 - 6.3e-32 111.0 0.0 1.1e-31 110.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CDJ94231.1 - 1.8e-22 79.3 0.3 3.8e-22 78.3 0.3 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 CDJ94231.1 - 3.4e-14 52.6 0.0 7.5e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Tir_receptor_N PF07490.11 CDJ94231.1 - 0.22 11.3 0.0 0.33 10.7 0.0 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus CAP PF00188.26 CDJ94232.1 - 0.016 16.0 0.0 0.36 11.7 0.0 2.5 2 1 0 2 2 2 0 Cysteine-rich secretory protein family SBP_bac_3 PF00497.20 CDJ94232.1 - 0.068 12.6 0.0 0.097 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 LicD PF04991.13 CDJ94233.1 - 0.0049 17.0 0.3 0.027 14.6 0.0 1.9 2 0 0 2 2 2 1 LicD family Pkinase PF00069.25 CDJ94235.1 - 1e-28 100.5 0.0 2.3e-16 60.0 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ94235.1 - 4.1e-20 72.2 0.0 8.9e-19 67.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase RTP1_C1 PF10363.9 CDJ94235.1 - 0.0031 17.7 0.1 0.019 15.2 0.0 2.2 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 ABC1 PF03109.16 CDJ94235.1 - 0.0084 16.3 0.0 0.036 14.2 0.0 2.0 2 0 0 2 2 2 1 ABC1 family zf-C4 PF00105.18 CDJ94236.1 - 1.7e-28 98.9 16.3 1.7e-28 98.9 16.3 1.8 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ94236.1 - 3.2e-25 88.9 2.0 6.4e-23 81.4 2.0 2.2 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor GST_C_2 PF13410.6 CDJ94237.1 - 0.0012 18.8 0.0 0.0025 17.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RVT_1 PF00078.27 CDJ94238.1 - 1.2e-17 64.2 0.0 1.4e-17 64.0 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GRIN_C PF15235.6 CDJ94239.1 - 0.17 12.2 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 G protein-regulated inducer of neurite outgrowth C-terminus Sld5 PF05916.11 CDJ94240.1 - 4.2e-06 27.2 0.3 0.00022 21.6 0.2 2.3 2 1 0 2 2 2 2 GINS complex protein Atx10homo_assoc PF09759.9 CDJ94240.1 - 0.1 12.7 0.8 0.2 11.7 0.8 1.5 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain RVT_1 PF00078.27 CDJ94241.1 - 7.2e-14 51.8 0.0 1e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1340 PF07067.11 CDJ94241.1 - 0.032 13.6 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) Zot PF05707.12 CDJ94241.1 - 0.11 12.1 0.1 0.35 10.5 0.0 1.8 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Pecanex_C PF05041.15 CDJ94242.1 - 3.2e-74 249.3 0.0 4.3e-74 248.9 0.0 1.2 1 0 0 1 1 1 1 Pecanex protein (C-terminus) Sigma70_r4 PF04545.16 CDJ94244.1 - 0.0019 17.6 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Peptidase_S48 PF03574.15 CDJ94244.1 - 0.12 12.5 0.0 16 5.7 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S48 BAT2_N PF07001.11 CDJ94245.1 - 0.18 12.3 5.6 0.24 11.8 5.6 1.1 1 0 0 1 1 1 0 BAT2 N-terminus Mucin PF01456.17 CDJ94246.1 - 0.0086 16.1 4.1 0.012 15.6 4.1 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein Aldo_ket_red PF00248.21 CDJ94247.1 - 1.1e-33 116.7 0.0 1.5e-31 109.7 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family DUF5332 PF17266.2 CDJ94248.1 - 4.8e-51 172.4 16.5 5.5e-51 172.2 16.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5332) LpxI_N PF17930.1 CDJ94250.1 - 0.056 13.3 0.0 0.079 12.8 0.0 1.3 1 1 0 1 1 1 0 LpxI N-terminal domain 3HCDH_N PF02737.18 CDJ94250.1 - 0.12 12.3 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain rRNA_proc-arch PF13234.6 CDJ94252.1 - 2e-67 228.0 5.3 1.9e-66 224.8 3.7 2.6 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 CDJ94252.1 - 6.8e-55 185.2 1.0 1.8e-54 183.8 1.0 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 CDJ94252.1 - 3.2e-19 69.4 0.0 7.3e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ94252.1 - 7.1e-05 23.1 0.0 0.00041 20.7 0.0 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ94252.1 - 0.00047 20.2 0.0 0.0011 18.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 CDJ94252.1 - 0.03 13.4 0.1 0.078 12.0 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein PGBA_C PF15437.6 CDJ94252.1 - 3.3 8.1 10.0 27 5.2 1.1 2.9 1 1 1 2 2 2 0 Plasminogen-binding protein pgbA C-terminal CRF PF00473.17 CDJ94252.1 - 4.9 7.3 10.8 35 4.6 0.7 3.7 3 0 0 3 3 3 0 Corticotropin-releasing factor family Forkhead PF00250.18 CDJ94254.1 - 9e-35 118.8 0.2 1.2e-34 118.4 0.2 1.2 1 0 0 1 1 1 1 Forkhead domain Cir_Bir_Yir PF06022.11 CDJ94254.1 - 0.21 11.0 1.8 0.27 10.7 1.8 1.1 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir Vac7 PF12751.7 CDJ94255.1 - 4.1e-05 23.2 0.0 4.8e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 DUF1195 PF06708.11 CDJ94255.1 - 0.0034 17.2 0.1 0.0048 16.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1195) Glycophorin_A PF01102.18 CDJ94255.1 - 0.017 15.4 0.1 0.028 14.6 0.1 1.3 1 0 0 1 1 1 0 Glycophorin A DUF4711 PF15829.5 CDJ94255.1 - 0.018 15.0 0.3 0.025 14.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) TMEM154 PF15102.6 CDJ94255.1 - 0.034 14.1 0.1 0.051 13.5 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family TOM20_plant PF06552.12 CDJ94255.1 - 0.063 13.0 0.0 0.077 12.7 0.0 1.1 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 SNARE PF05739.19 CDJ94255.1 - 0.11 12.5 1.6 0.19 11.7 1.6 1.4 1 0 0 1 1 1 0 SNARE domain Pox_EPC_I2-L1 PF12575.8 CDJ94255.1 - 0.16 12.2 0.1 0.26 11.5 0.1 1.4 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 Vac7 PF12751.7 CDJ94256.1 - 0.0027 17.2 0.1 0.0036 16.8 0.1 1.1 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 SNARE PF05739.19 CDJ94256.1 - 0.04 13.9 1.8 0.099 12.7 1.8 1.6 1 0 0 1 1 1 0 SNARE domain SRCR PF00530.18 CDJ94257.1 - 2.3e-13 50.5 0.1 2.3e-12 47.3 0.0 2.1 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 CDJ94257.1 - 0.0026 18.3 0.2 0.0045 17.5 0.2 1.3 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain AAA PF00004.29 CDJ94258.1 - 3.2e-43 147.3 0.0 6.7e-43 146.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ94258.1 - 1.5e-11 43.9 0.1 2.9e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CDJ94258.1 - 4.9e-08 33.3 0.6 2.3e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 CDJ94258.1 - 7.7e-07 29.0 0.4 2.3e-06 27.4 0.4 1.9 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 CDJ94258.1 - 1.2e-06 28.5 0.0 4.4e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDJ94258.1 - 1.5e-05 25.3 0.3 0.0085 16.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ94258.1 - 1.6e-05 25.4 0.2 0.00035 21.0 0.1 2.7 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 CDJ94258.1 - 9.8e-05 22.2 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CDJ94258.1 - 0.00089 19.0 0.2 0.0021 17.8 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 CDJ94258.1 - 0.001 19.2 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 CDJ94258.1 - 0.0019 17.5 0.1 0.0046 16.2 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 CDJ94258.1 - 0.0029 18.1 0.1 0.011 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 CDJ94258.1 - 0.0043 16.5 0.0 0.061 12.8 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 CDJ94258.1 - 0.0067 15.8 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 CDJ94258.1 - 0.0099 15.2 0.3 0.037 13.4 0.0 2.0 3 0 0 3 3 3 1 KaiC AAA_28 PF13521.6 CDJ94258.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 CDJ94258.1 - 0.011 15.6 0.0 0.029 14.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RILP PF11461.8 CDJ94258.1 - 0.013 15.7 1.3 0.028 14.6 1.3 1.5 1 0 0 1 1 1 0 Rab interacting lysosomal protein AAA_17 PF13207.6 CDJ94258.1 - 0.022 15.2 0.7 0.73 10.3 0.0 2.7 3 0 0 3 3 2 0 AAA domain Sigma54_activat PF00158.26 CDJ94258.1 - 0.025 14.3 0.1 0.12 12.1 0.0 2.2 2 1 0 2 2 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 CDJ94258.1 - 0.034 13.7 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 CDJ94258.1 - 0.058 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDJ94258.1 - 0.059 13.9 0.2 0.53 10.8 0.0 2.6 2 1 0 2 2 2 0 ABC transporter TsaE PF02367.17 CDJ94258.1 - 0.063 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 CDJ94258.1 - 0.069 12.3 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 CDJ94258.1 - 0.085 12.4 0.1 0.25 10.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.6 CDJ94258.1 - 0.092 13.1 0.2 0.25 11.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CDJ94258.1 - 0.1 12.3 0.1 0.27 10.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CDJ94258.1 - 0.11 11.7 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 CDJ94258.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF2072 PF09845.9 CDJ94258.1 - 0.13 12.5 1.1 0.23 11.7 1.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein Sigma54_activ_2 PF14532.6 CDJ94258.1 - 0.14 12.2 0.3 1 9.5 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain Spc24 PF08286.11 CDJ94258.1 - 0.15 12.3 0.6 0.39 11.0 0.6 1.7 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 SlyX PF04102.12 CDJ94258.1 - 0.17 12.5 2.5 0.48 11.1 2.5 1.8 1 0 0 1 1 1 0 SlyX HR1 PF02185.16 CDJ94258.1 - 0.18 12.0 4.8 0.45 10.7 4.8 1.7 1 0 0 1 1 1 0 Hr1 repeat FlxA PF14282.6 CDJ94258.1 - 0.19 11.8 2.3 0.61 10.1 1.6 2.0 2 0 0 2 2 2 0 FlxA-like protein Parvo_NS1 PF01057.17 CDJ94258.1 - 0.19 10.8 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 CDJ94258.1 - 0.2 11.4 1.0 0.77 9.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain V-SNARE PF05008.15 CDJ94258.1 - 0.32 11.4 4.0 0.25 11.8 1.5 2.1 3 0 0 3 3 1 0 Vesicle transport v-SNARE protein N-terminus DivIC PF04977.15 CDJ94258.1 - 0.32 10.8 2.0 0.73 9.6 2.0 1.6 1 0 0 1 1 1 0 Septum formation initiator Osmo_CC PF08946.10 CDJ94258.1 - 0.51 10.6 3.0 1.1 9.5 0.5 2.6 2 1 0 2 2 2 0 Osmosensory transporter coiled coil NPV_P10 PF05531.12 CDJ94258.1 - 0.56 10.7 2.8 1.9 9.0 0.9 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Histone PF00125.24 CDJ94259.1 - 9.7e-53 178.0 1.5 9.7e-53 178.0 1.5 1.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CDJ94259.1 - 0.0001 22.4 0.0 0.00022 21.3 0.0 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 CDJ94259.1 - 0.00039 20.7 0.0 0.00064 20.1 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 CDJ94259.1 - 0.0011 19.5 2.3 0.0011 19.5 2.3 1.7 2 0 0 2 2 2 1 PCNA-associated factor histone like domain DUF1179 PF06678.11 CDJ94259.1 - 0.0025 17.8 0.5 0.0043 17.0 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1179) TFIID-31kDa PF02291.15 CDJ94259.1 - 0.06 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 CDJ94259.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_S4 PF00163.19 CDJ94260.1 - 0.00013 22.8 0.3 0.00016 22.5 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Topoisom_bac PF01131.20 CDJ94260.1 - 0.011 14.8 0.3 0.013 14.5 0.3 1.0 1 0 0 1 1 1 0 DNA topoisomerase ShK PF01549.24 CDJ94261.1 - 0.002 18.6 2.4 0.0037 17.8 2.4 1.5 1 0 0 1 1 1 1 ShK domain-like Phage_holin_3_6 PF07332.11 CDJ94261.1 - 0.13 12.3 0.1 0.15 12.1 0.1 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Zn_ribbon_17 PF17120.5 CDJ94261.1 - 0.2 11.3 3.5 0.43 10.2 3.5 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type COG7 PF10191.9 CDJ94261.1 - 0.25 9.5 0.1 0.3 9.3 0.1 1.0 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) DUF4199 PF13858.6 CDJ94261.1 - 0.3 11.5 4.3 0.35 11.3 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Neur_chan_LBD PF02931.23 CDJ94263.1 - 2.6e-42 144.7 0.4 3.3e-42 144.4 0.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ94263.1 - 8.5e-23 81.6 5.0 1.2e-19 71.3 0.6 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DDE_3 PF13358.6 CDJ94264.1 - 1.9e-08 34.2 0.0 2.1e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Tub PF01167.18 CDJ94265.1 - 0.019 14.7 0.0 0.021 14.6 0.0 1.1 1 0 0 1 1 1 0 Tub family Peptidase_M60 PF13402.6 CDJ94265.1 - 0.077 12.5 0.6 0.16 11.5 0.2 1.8 1 1 0 1 1 1 0 Peptidase M60, enhancin and enhancin-like 7TM_GPCR_Srsx PF10320.9 CDJ94269.1 - 2.5e-06 27.1 17.0 3.7e-06 26.5 15.7 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srbc PF10316.9 CDJ94269.1 - 0.00081 19.0 5.0 0.00081 19.0 5.0 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7tm_1 PF00001.21 CDJ94269.1 - 0.0048 16.3 12.3 0.02 14.2 5.4 2.4 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.15 CDJ94269.1 - 0.096 12.7 4.6 1.2 9.1 0.7 2.5 1 1 1 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa PGBA_C PF15437.6 CDJ94270.1 - 0.78 10.1 9.3 0.13 12.7 0.5 3.1 3 0 0 3 3 3 0 Plasminogen-binding protein pgbA C-terminal RVT_1 PF00078.27 CDJ94271.1 - 2.9e-06 27.0 0.1 3.1e-06 26.9 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TROVE PF05731.11 CDJ94273.1 - 8.4e-73 245.9 0.3 1.9e-70 238.1 0.0 2.2 1 1 1 2 2 2 2 TROVE domain SH2 PF00017.24 CDJ94273.1 - 0.038 14.1 0.0 0.092 12.9 0.0 1.6 1 0 0 1 1 1 0 SH2 domain DUF272 PF03312.15 CDJ94274.1 - 1e-11 45.1 0.0 1.4e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF272) ATP-synt_S1 PF05827.12 CDJ94276.1 - 6.7e-19 68.2 2.5 2.4e-18 66.3 2.5 1.9 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Amastin PF07344.11 CDJ94276.1 - 0.014 15.2 0.1 0.024 14.5 0.1 1.4 1 0 0 1 1 1 0 Amastin surface glycoprotein Peptidase_S9 PF00326.21 CDJ94276.1 - 0.078 12.4 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF3737 PF12541.8 CDJ94276.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3737) Exo_endo_phos PF03372.23 CDJ94278.1 - 1.1e-05 25.0 0.0 2.7e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 CDJ94279.1 - 1.4e-16 60.7 0.0 2.8e-16 59.7 0.0 1.5 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CDJ94281.1 - 4.9e-12 45.8 0.0 5.7e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mucin PF01456.17 CDJ94283.1 - 0.76 9.8 18.7 1 9.3 18.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein TMEM119 PF15724.5 CDJ94283.1 - 5.1 7.1 0.0 5.1 7.1 0.0 2.2 1 1 1 2 2 2 0 TMEM119 family DUF273 PF03314.14 CDJ94284.1 - 1.1e-39 136.3 0.5 1.4e-39 136.0 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF273 PolyA_pol PF01743.20 CDJ94284.1 - 0.16 12.4 0.0 0.26 11.7 0.0 1.4 1 1 0 1 1 1 0 Poly A polymerase head domain RhoGEF PF00621.20 CDJ94286.1 - 2.8e-37 128.7 0.9 5.4e-37 127.8 0.2 1.9 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 CDJ94286.1 - 4.5e-05 23.9 0.0 0.0001 22.8 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_10 PF15411.6 CDJ94286.1 - 0.015 15.5 0.0 0.057 13.7 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain eRF1_1 PF03463.15 CDJ94286.1 - 0.083 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 eRF1 domain 1 Ion_trans_2 PF07885.16 CDJ94288.1 - 3.3e-35 119.9 20.6 5.5e-18 64.7 3.2 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 CDJ94288.1 - 1.6e-12 47.2 5.5 1.8e-09 37.2 0.2 2.2 2 0 0 2 2 2 2 Ion transport protein IRK PF01007.20 CDJ94288.1 - 0.0029 17.4 5.2 0.14 12.0 0.1 2.5 2 1 0 2 2 2 2 Inward rectifier potassium channel transmembrane domain DUF1774 PF08611.10 CDJ94288.1 - 0.91 9.9 5.9 0.33 11.3 0.6 2.7 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF1774) AAA_30 PF13604.6 CDJ94289.1 - 2.6e-09 37.1 0.1 0.00086 19.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CDJ94289.1 - 2.3e-08 34.5 0.1 7.9e-08 32.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ94289.1 - 2.9e-06 27.3 0.1 1.8e-05 24.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 CDJ94289.1 - 7e-05 22.7 0.1 0.013 15.4 0.0 2.4 2 0 0 2 2 2 2 Helicase DEAD PF00270.29 CDJ94289.1 - 0.00021 21.1 0.5 0.012 15.4 0.5 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.16 CDJ94289.1 - 0.00026 20.5 0.4 0.0036 16.8 0.8 2.1 2 0 0 2 2 2 1 PhoH-like protein AAA_12 PF13087.6 CDJ94289.1 - 0.0099 15.5 0.0 0.023 14.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CDJ94289.1 - 0.018 15.0 0.7 0.1 12.6 0.5 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Mucin PF01456.17 CDJ94290.1 - 0.0056 16.7 38.0 0.0086 16.1 38.0 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein CAP PF00188.26 CDJ94291.1 - 5.8e-16 59.5 3.6 7.9e-16 59.0 3.6 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ94291.1 - 0.043 14.1 4.9 1.2 9.4 1.1 2.8 2 1 1 3 3 3 0 Ancylostoma-associated secreted protein related Mitofilin PF09731.9 CDJ94292.1 - 8.9e-137 457.6 22.9 1e-136 457.4 22.9 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein 7tm_1 PF00001.21 CDJ94293.1 - 4.6e-14 52.4 0.3 4.6e-14 52.4 0.3 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) TRAPPC-Trs85 PF12739.7 CDJ94294.1 - 4e-83 279.7 5.0 5.3e-83 279.3 5.0 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_1 PF00515.28 CDJ94294.1 - 0.072 12.9 0.4 1.1 9.3 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat RPN7 PF10602.9 CDJ94294.1 - 0.11 12.2 0.9 0.31 10.7 0.1 2.1 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_2 PF07719.17 CDJ94294.1 - 0.19 11.9 3.0 3.7 7.9 1.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat V-ATPase_G PF03179.15 CDJ94295.1 - 1.5e-35 121.9 19.4 1.7e-35 121.7 19.4 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3086 PF11285.8 CDJ94295.1 - 0.036 13.2 4.3 0.043 12.9 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) 4HB_MCP_1 PF12729.7 CDJ94295.1 - 0.23 11.0 8.8 0.4 10.2 8.8 1.5 1 1 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF3552 PF12072.8 CDJ94295.1 - 0.32 10.4 23.0 0.2 11.0 14.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF4407 PF14362.6 CDJ94295.1 - 1.2 8.4 10.6 1.3 8.3 10.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V-ATPase_G_2 PF16999.5 CDJ94295.1 - 1.3 9.5 17.3 1.7 9.1 17.3 1.2 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF1318 PF07027.12 CDJ94295.1 - 2.1 8.9 9.2 1 9.8 6.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1318) DUF5401 PF17380.2 CDJ94295.1 - 4.4 5.2 19.7 5.3 5.0 19.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) ubiquitin PF00240.23 CDJ94296.1 - 2.7e-06 27.1 0.3 1.7e-05 24.5 0.3 1.9 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 CDJ94296.1 - 0.00037 20.9 0.2 0.0018 18.7 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 CDJ94296.1 - 0.019 14.8 0.2 0.062 13.1 0.2 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CDJ94296.1 - 0.062 13.3 0.2 0.22 11.6 0.2 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain DAGK_cat PF00781.24 CDJ94297.1 - 9.2e-19 67.3 0.0 1.6e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Moulting_cycle PF04870.16 CDJ94298.1 - 1.4e-62 212.1 8.1 1.6e-62 211.8 8.1 1.1 1 0 0 1 1 1 1 Moulting cycle Calponin PF00402.18 CDJ94299.1 - 6.7e-53 175.9 34.4 1.9e-11 43.4 0.8 6.2 6 0 0 6 6 6 6 Calponin family repeat RRM_3 PF08777.11 CDJ94301.1 - 1.2e-26 92.7 11.2 2e-24 85.6 0.5 2.7 2 0 0 2 2 2 2 RNA binding motif La PF05383.17 CDJ94301.1 - 9.8e-21 73.6 0.0 2e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CDJ94301.1 - 8.3e-13 48.0 1.0 1.6e-08 34.3 0.2 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Di19_C PF14571.6 CDJ94301.1 - 0.19 12.2 2.1 0.33 11.5 1.3 1.8 1 1 0 1 1 1 0 Stress-induced protein Di19, C-terminal PAP_RNA-bind PF04926.15 CDJ94301.1 - 0.48 10.0 5.4 2.4 7.8 5.3 2.1 1 1 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain GNT-I PF03071.15 CDJ94302.1 - 5.4e-148 493.3 0.7 6.3e-148 493.1 0.7 1.0 1 0 0 1 1 1 1 GNT-I family TRAF_BIRC3_bd PF16673.5 CDJ94302.1 - 0.031 14.1 0.6 0.066 13.0 0.6 1.5 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Pkinase_Tyr PF07714.17 CDJ94303.1 - 4e-73 245.9 0.0 5.9e-73 245.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ94303.1 - 1.5e-46 158.9 0.0 2.3e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDJ94303.1 - 5.4e-09 36.0 0.0 1.2e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 SH2 domain Kinase-like PF14531.6 CDJ94303.1 - 0.00018 20.9 0.0 0.00038 19.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDJ94303.1 - 0.029 13.7 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family B2 PF11473.8 CDJ94303.1 - 0.051 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA binding protein B2 PQ-loop PF04193.14 CDJ94305.1 - 5.8e-19 67.6 6.0 1.1e-18 66.7 6.0 1.5 1 0 0 1 1 1 1 PQ loop repeat ST7 PF04184.12 CDJ94305.1 - 7.1e-06 24.8 0.2 1.1e-05 24.2 0.2 1.1 1 0 0 1 1 1 1 ST7 protein RNA_pol_Rpb2_1 PF04563.15 CDJ94306.1 - 2.2e-58 197.1 0.1 2.7e-58 196.8 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase beta subunit SPRY PF00622.28 CDJ94307.1 - 5.9e-14 52.2 0.0 8.3e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 SPRY domain F-box-like PF12937.7 CDJ94307.1 - 3.4e-12 46.0 1.3 5.7e-12 45.3 1.3 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDJ94307.1 - 8.5e-08 31.9 1.7 1.6e-07 31.0 1.7 1.4 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 CDJ94307.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 F-box Ribosomal_L3 PF00297.22 CDJ94308.1 - 7.2e-20 71.3 4.7 3.1e-16 59.3 4.0 2.6 2 1 0 2 2 2 1 Ribosomal protein L3 Rcd1 PF04078.13 CDJ94309.1 - 2.4e-130 433.4 0.8 2.8e-130 433.2 0.8 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Cupin_8 PF13621.6 CDJ94310.1 - 5.1e-08 32.9 0.7 2e-07 31.0 0.3 2.0 2 0 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 CDJ94310.1 - 1.2e-06 28.9 0.4 4e-06 27.2 0.1 2.0 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 CDJ94310.1 - 8.3e-05 22.2 0.2 0.0004 19.9 0.2 2.0 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 CDJ94310.1 - 0.059 13.1 0.2 0.21 11.3 0.0 2.0 3 0 0 3 3 3 0 Cupin domain PhyH PF05721.13 CDJ94310.1 - 0.17 12.1 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) EAP30 PF04157.16 CDJ94311.1 - 5.7e-71 238.5 0.2 8.8e-71 237.9 0.2 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family Methyltransf_11 PF08241.12 CDJ94311.1 - 1.9e-10 41.2 0.0 4.9e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ94311.1 - 3.1e-10 40.6 0.4 9.5e-10 39.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ94311.1 - 6.1e-06 26.2 0.0 1.6e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ94311.1 - 9.8e-05 23.0 0.0 0.00026 21.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ94311.1 - 0.00033 20.5 0.0 0.00083 19.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CDJ94311.1 - 0.029 14.1 0.0 0.065 13.0 0.0 1.6 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 CDJ94311.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Pigment_DH PF06324.11 CDJ94312.1 - 0.0091 16.0 4.7 0.94 9.7 0.8 2.5 2 0 0 2 2 2 2 Pigment-dispersing hormone (PDH) LRRFIP PF09738.9 CDJ94313.1 - 2e-45 155.5 19.7 2e-45 155.5 19.7 3.1 2 1 1 3 3 3 1 LRRFIP family ATG16 PF08614.11 CDJ94313.1 - 7.6e-07 29.6 20.5 7.6e-07 29.6 20.5 3.5 2 1 1 3 3 3 2 Autophagy protein 16 (ATG16) FPP PF05911.11 CDJ94313.1 - 0.0028 16.0 15.7 0.0028 16.0 15.7 2.3 2 1 0 2 2 2 1 Filament-like plant protein, long coiled-coil DUF3450 PF11932.8 CDJ94313.1 - 0.0073 15.6 6.4 0.0073 15.6 6.4 4.2 3 1 1 4 4 4 2 Protein of unknown function (DUF3450) Fez1 PF06818.15 CDJ94313.1 - 0.023 15.2 15.6 0.023 15.2 15.6 3.8 1 1 1 2 2 1 0 Fez1 FlaC_arch PF05377.11 CDJ94313.1 - 0.047 14.1 29.0 0.32 11.4 0.9 5.8 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) DUF812 PF05667.11 CDJ94313.1 - 0.13 11.1 42.0 0.66 8.8 15.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DUF1664 PF07889.12 CDJ94313.1 - 1.2 9.2 29.9 0.12 12.4 1.8 5.1 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 CDJ94313.1 - 3.7 7.9 11.0 7.9 6.8 0.7 4.0 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) HAP1_N PF04849.13 CDJ94313.1 - 4.7 6.3 46.1 0.0094 15.2 30.0 2.7 1 1 0 2 2 2 0 HAP1 N-terminal conserved region Spc7 PF08317.11 CDJ94313.1 - 8.4 5.2 51.9 0.14 11.1 16.8 3.3 2 2 0 2 2 2 0 Spc7 kinetochore protein ERM PF00769.19 CDJ94313.1 - 9.7 5.9 57.2 3.3 7.4 26.2 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Rep_fac_C PF08542.11 CDJ94314.1 - 1.6e-23 82.9 0.0 6e-23 81.1 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 CDJ94314.1 - 5.9e-14 52.6 0.0 9.7e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CDJ94314.1 - 1.3e-11 44.5 0.1 1.2e-10 41.4 0.3 2.3 2 1 1 3 3 3 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 CDJ94314.1 - 7.6e-09 35.7 0.0 1.4e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 CDJ94314.1 - 2.7e-07 30.7 0.0 1.2e-06 28.6 0.0 2.0 1 1 1 2 2 2 1 Rad17 P-loop domain Viral_helicase1 PF01443.18 CDJ94314.1 - 8.2e-07 29.0 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 CDJ94314.1 - 1.2e-05 25.1 0.0 3.3e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDJ94314.1 - 1.7e-05 25.3 0.0 0.0045 17.4 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain DNA_pol3_delta PF06144.13 CDJ94314.1 - 3.4e-05 23.7 0.2 6.5e-05 22.8 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 CDJ94314.1 - 0.00012 22.4 0.1 0.29 11.4 0.0 2.5 1 1 1 2 2 2 2 AAA domain DEAD PF00270.29 CDJ94314.1 - 0.00021 21.1 0.1 0.079 12.7 0.0 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_assoc_2 PF16193.5 CDJ94314.1 - 0.00021 21.6 0.0 0.00056 20.2 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 CDJ94314.1 - 0.00025 20.9 0.0 0.00035 20.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDJ94314.1 - 0.00056 20.1 0.1 0.0011 19.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CDJ94314.1 - 0.0017 18.7 0.1 0.013 15.8 0.0 2.4 2 1 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 CDJ94314.1 - 0.0022 17.7 0.0 0.0047 16.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ94314.1 - 0.0059 17.0 0.5 0.39 11.1 0.2 2.6 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.11 CDJ94314.1 - 0.011 15.7 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CDJ94314.1 - 0.016 14.6 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 CDJ94314.1 - 0.018 14.3 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Poty_coat PF00767.18 CDJ94314.1 - 0.02 14.4 0.1 5.8 6.4 0.0 2.3 1 1 1 2 2 2 0 Potyvirus coat protein AAA_18 PF13238.6 CDJ94314.1 - 0.025 15.1 0.0 0.045 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CDJ94314.1 - 0.025 14.3 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 CDJ94314.1 - 0.028 14.4 0.0 9.6 6.2 0.0 2.9 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_5 PF07728.14 CDJ94314.1 - 0.03 14.3 0.1 0.11 12.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 CDJ94314.1 - 0.031 14.8 0.0 0.089 13.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 CDJ94314.1 - 0.038 14.5 0.2 0.092 13.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CDJ94314.1 - 0.042 13.8 0.1 0.44 10.5 0.0 2.2 1 1 1 2 2 2 0 NTPase DUF815 PF05673.13 CDJ94314.1 - 0.06 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TniB PF05621.11 CDJ94314.1 - 0.077 12.4 0.0 11 5.4 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein IstB_IS21 PF01695.17 CDJ94314.1 - 0.08 12.7 0.0 0.19 11.5 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 CDJ94314.1 - 0.085 13.1 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain UbiA PF01040.18 CDJ94315.1 - 8.8e-48 162.8 13.3 1.2e-47 162.4 13.3 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Ost4 PF10215.9 CDJ94315.1 - 0.025 14.4 1.3 0.084 12.7 0.1 2.4 2 0 0 2 2 2 0 Oligosaccaryltransferase Bystin PF05291.11 CDJ94316.1 - 2.8e-131 437.1 0.1 4.1e-131 436.6 0.1 1.2 1 0 0 1 1 1 1 Bystin Guanylate_kin PF00625.21 CDJ94319.1 - 1.7e-59 200.6 0.0 1.9e-59 200.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 CDJ94319.1 - 5.2e-05 23.8 0.0 0.0001 22.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ94319.1 - 0.00047 20.6 0.2 0.0015 18.9 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CDJ94319.1 - 0.0018 18.4 0.4 0.014 15.6 0.4 2.0 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CDJ94319.1 - 0.0021 18.6 0.5 0.11 13.1 0.5 2.2 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 CDJ94319.1 - 0.012 15.8 0.6 0.088 13.1 0.0 2.4 3 1 0 3 3 3 0 AAA domain Rad17 PF03215.15 CDJ94319.1 - 0.017 15.1 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 CDJ94319.1 - 0.049 13.4 0.1 0.096 12.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 CDJ94319.1 - 0.12 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TRF PF08558.10 CDJ94319.1 - 0.13 11.9 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) RsgA_GTPase PF03193.16 CDJ94319.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 CDJ94319.1 - 0.14 12.2 0.1 1.9 8.5 0.0 2.5 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CDJ94319.1 - 0.15 12.5 0.1 0.31 11.4 0.1 1.7 1 1 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 CDJ94319.1 - 0.2 12.2 2.0 1.9 9.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain zf-CCHC PF00098.23 CDJ94320.1 - 3.1e-05 23.8 1.8 4.8e-05 23.2 1.8 1.3 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 CDJ94320.1 - 0.042 14.4 0.0 0.15 12.7 0.0 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ94320.1 - 0.11 12.9 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_2 PF13696.6 CDJ94320.1 - 0.29 11.0 2.4 0.44 10.4 2.4 1.3 1 0 0 1 1 1 0 Zinc knuckle Cathelicidins PF00666.17 CDJ94321.1 - 0.049 13.9 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 Cathelicidin DUF2201_N PF13203.6 CDJ94321.1 - 0.14 11.7 3.6 0.24 11.0 3.6 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Hormone_recep PF00104.30 CDJ94322.1 - 4.9e-29 101.4 0.1 7.9e-29 100.7 0.1 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 CDJ94322.1 - 1e-27 96.4 17.9 1e-27 96.4 17.9 1.9 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) RIO1 PF01163.22 CDJ94323.1 - 1.2e-71 240.3 0.2 2.2e-71 239.3 0.0 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 CDJ94323.1 - 7.3e-05 22.8 0.1 0.11 12.4 0.0 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ94323.1 - 0.85 8.3 7.8 0.016 14.0 0.8 1.8 2 1 0 2 2 2 0 Fungal protein kinase CorA PF01544.18 CDJ94324.1 - 1.6 7.9 5.3 3.7 6.8 5.3 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Abhydrolase_1 PF00561.20 CDJ94325.1 - 8.7e-20 71.4 0.0 2.6e-14 53.5 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ94325.1 - 2.4e-18 67.5 0.0 3.1e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDJ94325.1 - 1.9e-13 50.2 0.0 1.6e-12 47.3 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 CDJ94325.1 - 2.2e-06 28.0 0.0 3.8e-06 27.2 0.0 1.3 1 1 0 1 1 1 1 Thioesterase domain Lipase_2 PF01674.18 CDJ94325.1 - 0.00021 20.9 0.0 0.00031 20.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 2) PGAP1 PF07819.13 CDJ94325.1 - 0.00025 20.8 0.0 0.0012 18.6 0.0 1.9 1 1 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 CDJ94325.1 - 0.00099 19.0 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_3 PF07859.13 CDJ94325.1 - 0.025 14.5 0.0 0.03 14.2 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.14 CDJ94325.1 - 0.032 13.7 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Say1_Mug180 PF10340.9 CDJ94325.1 - 0.088 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase U83 PF17465.2 CDJ94326.1 - 0.029 14.5 0.1 0.06 13.5 0.0 1.5 1 1 0 1 1 1 0 Chemokine-like protein, HHV-6 U83 gene product Guanylate_cyc PF00211.20 CDJ94328.1 - 1.3e-62 210.6 0.0 2.1e-62 210.0 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase PF00069.25 CDJ94328.1 - 1.1e-10 41.4 0.0 1.9e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ94328.1 - 5.7e-09 35.6 0.0 9.6e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HNOBA PF07701.14 CDJ94328.1 - 2.1e-06 27.3 0.5 3.2e-06 26.7 0.5 1.3 1 0 0 1 1 1 1 Heme NO binding associated ISPD_C PF18706.1 CDJ94328.1 - 0.009 15.7 0.4 0.015 14.9 0.4 1.3 1 0 0 1 1 1 1 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain AMP-binding PF00501.28 CDJ94328.1 - 0.092 11.3 0.0 0.15 10.6 0.0 1.3 1 0 0 1 1 1 0 AMP-binding enzyme CRS1_YhbY PF01985.21 CDJ94328.1 - 0.1 12.8 0.4 0.28 11.4 0.4 1.8 1 0 0 1 1 1 0 CRS1 / YhbY (CRM) domain RE_ApaLI PF09499.10 CDJ94328.1 - 0.14 11.8 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease TPT PF03151.16 CDJ94329.1 - 1.1e-11 44.7 19.5 1.3e-11 44.4 19.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 CDJ94329.1 - 0.00038 19.8 25.7 0.00054 19.3 25.7 1.2 1 0 0 1 1 1 1 UAA transporter family Surp PF01805.20 CDJ94330.1 - 4.3e-17 61.9 0.1 8e-17 61.0 0.1 1.5 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 CDJ94330.1 - 3.9e-12 45.8 0.0 8.7e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Takusan PF04822.13 CDJ94330.1 - 0.12 12.3 0.1 0.12 12.3 0.1 3.4 4 0 0 4 4 4 0 Takusan RRM_7 PF16367.5 CDJ94330.1 - 0.16 12.1 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif CCDC92 PF14916.6 CDJ94331.1 - 0.025 14.3 0.5 2.3 8.0 0.2 2.4 2 0 0 2 2 2 0 Coiled-coil domain of unknown function Ion_trans_2 PF07885.16 CDJ94332.1 - 9.8e-14 51.1 25.2 1.1e-08 34.9 5.5 3.1 3 0 0 3 3 3 2 Ion channel MarC PF01914.17 CDJ94332.1 - 0.074 12.4 0.4 0.13 11.6 0.4 1.3 1 0 0 1 1 1 0 MarC family integral membrane protein Ion_trans_2 PF07885.16 CDJ94333.1 - 1.7e-18 66.4 21.8 1.5e-11 44.1 5.3 2.8 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CDJ94333.1 - 3.2e-05 23.3 8.6 0.025 13.8 0.1 2.3 1 1 0 2 2 2 2 Ion transport protein Innexin PF00876.18 CDJ94335.1 - 2.1e-07 30.6 0.2 2.8e-07 30.2 0.2 1.1 1 0 0 1 1 1 1 Innexin ArfGap PF01412.18 CDJ94336.1 - 7.6e-27 93.7 0.1 3e-26 91.8 0.1 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf GIT_SHD PF08518.11 CDJ94336.1 - 6.4e-16 57.7 4.4 1.5e-07 30.9 0.6 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT_CC PF16559.5 CDJ94336.1 - 2.9e-10 39.9 0.6 6.3e-10 38.8 0.6 1.6 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor GIT1_C PF12205.8 CDJ94336.1 - 8.3e-09 35.6 8.4 1.5e-08 34.7 2.8 3.3 2 1 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term Ank_5 PF13857.6 CDJ94336.1 - 9.9e-06 25.7 0.2 3.2e-05 24.1 0.2 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDJ94336.1 - 8.4e-05 23.0 0.1 0.0019 18.7 0.0 3.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ94336.1 - 0.0013 19.3 0.2 0.012 16.2 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ94336.1 - 0.0027 18.1 0.0 0.083 13.4 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat DUF4891 PF16232.5 CDJ94336.1 - 0.071 13.6 0.1 0.21 12.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4891) TackOD1 PF18551.1 CDJ94336.1 - 0.074 12.7 0.5 0.26 11.0 0.3 2.0 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 MFS_1 PF07690.16 CDJ94337.1 - 5.3e-19 68.3 45.7 8.9e-19 67.6 39.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-RING_2 PF13639.6 CDJ94339.1 - 2.9e-08 33.9 14.9 5.5e-08 33.0 7.9 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 CDJ94339.1 - 6.2e-06 25.8 4.5 6.2e-06 25.8 4.5 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CDJ94339.1 - 0.00017 21.4 11.6 0.00056 19.7 8.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RNF220 PF15926.5 CDJ94339.1 - 0.00048 19.8 0.1 0.00061 19.5 0.1 1.2 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 Vps39_2 PF10367.9 CDJ94339.1 - 0.0019 18.6 2.6 0.14 12.6 0.7 2.2 1 1 1 2 2 2 1 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 CDJ94339.1 - 0.0021 17.7 5.0 0.0021 17.7 5.0 1.8 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 CDJ94339.1 - 0.0041 17.1 7.7 0.0041 17.1 7.7 2.4 2 0 0 2 2 2 1 RING-type zinc-finger PRP21_like_P PF12230.8 CDJ94339.1 - 0.0049 16.8 0.0 0.0051 16.7 0.0 1.1 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein zf-rbx1 PF12678.7 CDJ94339.1 - 0.014 15.6 13.2 0.019 15.2 9.1 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CDJ94339.1 - 0.025 14.5 10.6 1.7 8.6 7.1 2.3 2 0 0 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.8 CDJ94339.1 - 0.048 13.8 9.6 0.28 11.4 6.5 2.4 2 0 0 2 2 2 0 FANCL C-terminal domain zf_UBZ PF18439.1 CDJ94339.1 - 0.069 12.8 2.3 0.076 12.6 0.4 2.0 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C3HC4 PF00097.25 CDJ94339.1 - 0.13 12.2 13.9 0.11 12.4 9.0 2.4 3 0 0 3 3 2 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_16 PF17034.5 CDJ94339.1 - 0.19 11.9 4.1 0.37 11.0 4.1 1.5 1 1 0 1 1 1 0 Zinc-ribbon like family zf-C3HC4_3 PF13920.6 CDJ94339.1 - 0.68 9.8 16.1 0.9 9.4 7.1 2.6 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDJ94339.1 - 0.9 9.5 0.0 0.9 9.5 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 CDJ94339.1 - 0.99 9.8 9.8 0.35 11.2 6.1 2.0 2 0 0 2 2 2 0 RING-like domain RINGv PF12906.7 CDJ94339.1 - 5.2 7.3 13.9 2.8 8.2 8.7 2.4 2 0 0 2 2 2 0 RING-variant domain Adaptin_binding PF10199.9 CDJ94340.1 - 0.0046 17.6 2.0 0.025 15.2 2.0 2.3 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Vpu PF00558.19 CDJ94340.1 - 0.0052 16.5 0.2 0.011 15.5 0.2 1.4 1 0 0 1 1 1 1 Vpu protein Ribosomal_L1 PF00687.21 CDJ94341.1 - 3e-45 154.5 3.1 3.5e-45 154.2 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Snf7 PF03357.21 CDJ94343.1 - 2.2e-18 66.4 10.9 3.1e-18 65.9 10.9 1.2 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 CDJ94343.1 - 0.0005 20.0 8.2 0.00067 19.6 8.2 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway ArAE_1_C PF11728.8 CDJ94343.1 - 0.32 11.0 6.5 0.84 9.6 5.2 2.1 1 1 1 2 2 2 0 Putative aromatic acid exporter C-terminal domain DUF4795 PF16043.5 CDJ94343.1 - 0.46 10.1 12.2 0.057 13.0 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF4813 PF16072.5 CDJ94343.1 - 0.5 10.0 4.1 0.089 12.4 0.6 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) ETF PF01012.21 CDJ94344.1 - 1e-46 159.1 1.9 1.3e-46 158.7 1.9 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain DUF812 PF05667.11 CDJ94345.1 - 0.0088 15.0 0.5 0.0099 14.8 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) IFT46_B_C PF12317.8 CDJ94345.1 - 0.013 15.3 0.1 0.015 15.1 0.1 1.1 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal PIN_8 PF18476.1 CDJ94345.1 - 0.052 13.4 0.5 0.064 13.1 0.5 1.1 1 0 0 1 1 1 0 PIN like domain Prp19 PF08606.11 CDJ94345.1 - 0.057 13.4 0.4 0.09 12.8 0.4 1.3 1 0 0 1 1 1 0 Prp19/Pso4-like LMBR1 PF04791.16 CDJ94345.1 - 0.093 11.6 0.2 0.11 11.4 0.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein APG6_N PF17675.1 CDJ94345.1 - 0.23 12.0 2.8 0.15 12.6 1.0 1.5 2 0 0 2 2 2 0 Apg6 coiled-coil region Motile_Sperm PF00635.26 CDJ94346.1 - 0.0011 18.8 0.0 0.0027 17.5 0.0 1.7 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Ant_C PF05586.11 CDJ94346.1 - 4.2 8.0 30.4 6.3 7.5 2.2 5.8 2 2 3 6 6 6 0 Anthrax receptor C-terminus region FERM_M PF00373.18 CDJ94347.1 - 0.00019 21.8 0.1 0.00028 21.3 0.1 1.3 1 0 0 1 1 1 1 FERM central domain FliG_C PF01706.16 CDJ94347.1 - 0.12 12.6 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 FliG C-terminal domain DUF3807 PF12720.7 CDJ94348.1 - 0.75 10.0 13.8 0.86 9.8 13.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) SCAPER_N PF16501.5 CDJ94349.1 - 2.9e-22 78.5 2.3 1e-21 76.7 1.0 2.7 2 0 0 2 2 2 1 S phase cyclin A-associated protein in the endoplasmic reticulum Stathmin PF00836.19 CDJ94349.1 - 0.0014 18.6 16.7 0.0014 18.6 16.7 4.8 5 0 0 5 5 5 1 Stathmin family Atx10homo_assoc PF09759.9 CDJ94350.1 - 1.6e-17 63.4 0.0 7e-17 61.3 0.0 2.1 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain UME PF08064.13 CDJ94350.1 - 0.056 13.4 0.0 0.17 11.8 0.0 1.9 1 0 0 1 1 1 0 UME (NUC010) domain C2 PF00168.30 CDJ94351.1 - 2.8e-07 30.8 0.0 6.4e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF1771 PF08590.10 CDJ94351.1 - 3.9 7.9 21.4 0.41 11.0 1.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1771) ABC_tran PF00005.27 CDJ94352.1 - 6.3e-58 195.2 0.0 8.2e-31 107.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CDJ94352.1 - 2.2e-40 138.8 50.7 4.2e-25 88.6 15.5 2.8 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 CDJ94352.1 - 1.3e-17 64.6 0.8 1.9e-06 27.9 0.0 4.5 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDJ94352.1 - 7.1e-06 25.6 0.0 0.28 10.6 0.0 3.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CDJ94352.1 - 2.5e-05 24.9 0.6 0.018 15.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC2_membrane_2 PF12679.7 CDJ94352.1 - 0.00015 21.2 21.1 0.025 13.9 0.3 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein SRP54 PF00448.22 CDJ94352.1 - 0.00031 20.4 2.7 0.29 10.7 0.0 2.7 3 0 0 3 3 3 2 SRP54-type protein, GTPase domain AAA_15 PF13175.6 CDJ94352.1 - 0.0021 17.9 0.0 1.7 8.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain MukB PF04310.12 CDJ94352.1 - 0.0044 16.9 0.3 0.47 10.2 0.0 2.4 2 0 0 2 2 2 1 MukB N-terminal DUF4162 PF13732.6 CDJ94352.1 - 0.011 16.4 0.5 1.4 9.7 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_29 PF13555.6 CDJ94352.1 - 0.013 15.2 0.6 1 9.2 0.1 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 CDJ94352.1 - 0.022 14.5 0.1 2 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CDJ94352.1 - 0.06 13.3 0.0 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain SbcCD_C PF13558.6 CDJ94352.1 - 0.14 12.4 0.0 21 5.4 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC2_membrane PF01061.24 CDJ94352.1 - 1.3 8.4 42.9 0.22 10.9 13.5 3.4 3 0 0 3 3 3 0 ABC-2 type transporter RRM_1 PF00076.22 CDJ94353.1 - 1.5e-23 82.4 0.0 1.7e-23 82.2 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ94353.1 - 0.015 15.2 0.0 0.031 14.1 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_5 PF13893.6 CDJ94353.1 - 0.045 13.4 0.0 0.045 13.3 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pyr_redox_dim PF02852.22 CDJ94353.1 - 0.058 13.7 0.0 0.067 13.5 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain RRM_1 PF00076.22 CDJ94354.1 - 6.9e-22 77.1 0.1 8.4e-22 76.8 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ94354.1 - 0.018 14.6 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_9 PF18444.1 CDJ94354.1 - 0.027 14.3 0.4 0.084 12.7 0.4 1.7 1 1 0 1 1 1 0 RNA recognition motif Pyr_redox_dim PF02852.22 CDJ94354.1 - 0.031 14.6 0.0 0.035 14.4 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain RRM_1 PF00076.22 CDJ94355.1 - 3.3e-24 84.5 0.0 3.9e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ94355.1 - 0.01 15.7 0.0 0.02 14.7 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif Pyr_redox_dim PF02852.22 CDJ94355.1 - 0.019 15.2 0.0 0.021 15.1 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain RRM_5 PF13893.6 CDJ94355.1 - 0.062 12.9 0.0 0.069 12.7 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CDJ94356.1 - 5.1e-23 80.7 0.0 5.9e-23 80.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ94356.1 - 0.0062 16.4 0.0 0.013 15.4 0.0 1.5 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 CDJ94356.1 - 0.02 14.5 0.0 0.022 14.3 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pyr_redox_dim PF02852.22 CDJ94356.1 - 0.052 13.8 0.0 0.056 13.7 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GPP34 PF05719.11 CDJ94357.1 - 5.8e-58 196.3 0.3 7.6e-58 195.9 0.3 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) zf-CCCH PF00642.24 CDJ94359.1 - 3.3e-18 65.1 21.4 1.7e-10 40.5 4.1 2.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ94359.1 - 4.8e-08 32.8 20.6 6.3e-05 22.9 5.4 2.8 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 CDJ94359.1 - 0.0018 18.0 14.8 0.12 12.2 3.4 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 CDJ94359.1 - 0.12 13.1 15.7 0.21 12.3 1.5 2.8 2 1 1 3 3 3 0 Torus domain zf-CCCH_2 PF14608.6 CDJ94359.1 - 0.22 12.1 15.5 1.4 9.5 3.9 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger oligo_HPY PF08352.12 CDJ94359.1 - 2 9.0 7.6 9.7 6.8 0.4 3.3 4 0 0 4 4 4 0 Oligopeptide/dipeptide transporter, C-terminal region Peptidase_M41 PF01434.18 CDJ94360.1 - 8.9e-67 224.6 2.2 1.8e-66 223.6 2.2 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CDJ94360.1 - 1.7e-44 151.4 0.0 3.8e-44 150.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ94360.1 - 4e-10 39.3 0.0 1.7e-09 37.3 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CDJ94360.1 - 1.2e-09 38.3 0.0 4.2e-09 36.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDJ94360.1 - 1.4e-05 25.6 0.1 0.00024 21.5 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 CDJ94360.1 - 3e-05 23.8 0.0 9.2e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CDJ94360.1 - 0.00011 21.5 0.0 0.00028 20.2 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 CDJ94360.1 - 0.00041 20.6 0.1 0.042 14.1 0.0 2.6 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CDJ94360.1 - 0.005 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 CDJ94360.1 - 0.006 16.0 0.0 0.024 14.0 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CDJ94360.1 - 0.0099 15.9 0.0 0.087 12.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CDJ94360.1 - 0.01 16.3 0.0 0.059 13.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 CDJ94360.1 - 0.01 15.9 0.0 0.039 14.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CDJ94360.1 - 0.011 15.9 0.0 0.031 14.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 CDJ94360.1 - 0.013 16.0 0.0 0.042 14.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 CDJ94360.1 - 0.017 14.7 0.0 0.048 13.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 CDJ94360.1 - 0.018 15.3 0.0 0.067 13.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDJ94360.1 - 0.044 14.3 0.1 0.18 12.3 0.0 2.0 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 CDJ94360.1 - 0.058 13.0 0.2 0.2 11.2 0.2 1.9 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CDJ94360.1 - 0.064 13.0 0.0 0.36 10.5 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 CDJ94360.1 - 0.11 12.1 0.1 0.41 10.3 0.0 2.1 3 0 0 3 3 1 0 AAA domain PhoH PF02562.16 CDJ94360.1 - 0.13 11.7 0.0 0.36 10.3 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 CDJ94360.1 - 0.13 12.1 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 CDJ94360.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FragX_IP PF05994.11 CDJ94361.1 - 4.9e-45 153.9 0.1 5.5e-45 153.8 0.1 1.0 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family Tho1_MOS11_C PF18592.1 CDJ94361.1 - 0.036 13.9 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Tho1/MOS11 C-terminal domain zf-B_box PF00643.24 CDJ94362.1 - 6.9e-13 48.5 13.4 6.2e-08 32.7 6.1 2.7 2 0 0 2 2 2 2 B-box zinc finger AIP3 PF03915.13 CDJ94362.1 - 5.5e-09 35.6 3.5 5.5e-09 35.6 3.5 2.6 2 1 0 2 2 2 1 Actin interacting protein 3 zf-UBR PF02207.20 CDJ94362.1 - 0.29 11.3 17.3 4.2 7.6 11.2 2.6 1 1 1 2 2 2 0 Putative zinc finger in N-recognin (UBR box) IBR PF01485.21 CDJ94362.1 - 0.32 11.2 11.0 0.083 13.1 4.9 2.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain TMEM144 PF07857.12 CDJ94364.1 - 2.2e-121 404.9 7.5 2.7e-121 404.6 7.5 1.1 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 CDJ94364.1 - 1.7e-09 37.4 3.6 1.7e-09 37.4 3.6 2.5 2 1 0 2 2 2 2 Sugar transport protein CytB6-F_Fe-S PF08802.10 CDJ94364.1 - 0.2 11.7 2.6 2.3 8.3 0.2 3.2 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit Ctr PF04145.15 CDJ94364.1 - 2.1 8.9 12.2 22 5.6 0.0 3.3 3 0 0 3 3 3 0 Ctr copper transporter family Vma12 PF11712.8 CDJ94364.1 - 2.2 8.3 6.2 0.78 9.8 0.1 2.9 4 0 0 4 4 4 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2070 PF09843.9 CDJ94365.1 - 0.081 11.2 8.4 0.12 10.6 8.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF148 PF02520.17 CDJ94366.1 - 0.062 13.4 4.4 0.082 13.0 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF148 Lipase_chap PF03280.14 CDJ94366.1 - 0.066 13.2 18.6 0.56 10.1 7.5 2.1 1 1 1 2 2 2 0 Proteobacterial lipase chaperone protein EMP24_GP25L PF01105.24 CDJ94367.1 - 7.5e-48 162.9 0.3 8.7e-48 162.7 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pex24p PF06398.11 CDJ94367.1 - 0.011 14.7 0.1 0.015 14.3 0.1 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin TRPM_tetra PF16519.5 CDJ94367.1 - 0.035 14.2 0.1 0.079 13.1 0.1 1.6 1 0 0 1 1 1 0 Tetramerisation domain of TRPM Yip1 PF04893.17 CDJ94368.1 - 4e-13 49.4 14.4 6.1e-13 48.8 14.4 1.3 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 CDJ94368.1 - 0.0024 17.7 5.8 0.0037 17.1 5.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) DUF2070 PF09843.9 CDJ94368.1 - 4.5 5.5 5.7 5.6 5.1 5.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) FSA_C PF10479.9 CDJ94369.1 - 0.06 11.5 4.6 0.089 10.9 4.6 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF3052 PF11253.8 CDJ94370.1 - 0.022 14.7 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) Reticulon PF02453.17 CDJ94371.1 - 0.0076 16.2 0.3 0.012 15.6 0.3 1.3 1 0 0 1 1 1 1 Reticulon zf-HC5HC2H PF13771.6 CDJ94373.1 - 4.7e-15 55.6 6.8 4.7e-15 55.6 6.8 2.7 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CDJ94373.1 - 6.3e-08 32.8 4.7 6.3e-08 32.8 4.7 2.7 2 1 1 3 3 3 1 PHD-zinc-finger like domain PSD2 PF07624.11 CDJ94373.1 - 0.074 12.8 0.0 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) MADF_DNA_bdg PF10545.9 CDJ94374.1 - 6e-17 61.7 0.6 1.8e-16 60.2 0.3 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 CDJ94374.1 - 1.3e-09 38.3 0.5 2.6e-09 37.3 0.5 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 CDJ94374.1 - 0.015 16.3 0.9 0.041 14.9 0.3 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Collagen PF01391.18 CDJ94375.1 - 0.00064 19.4 7.4 0.00064 19.4 7.4 1.6 2 0 0 2 2 1 1 Collagen triple helix repeat (20 copies) SHR3_chaperone PF08229.11 CDJ94375.1 - 0.00065 18.7 0.0 0.00088 18.3 0.0 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 PigN PF04987.14 CDJ94375.1 - 0.0015 17.5 0.0 0.0021 17.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) V_ATPase_I PF01496.19 CDJ94375.1 - 0.0018 16.3 0.0 0.0023 16.0 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family AP3D1 PF06375.11 CDJ94375.1 - 0.0019 18.4 7.1 0.0028 17.9 7.1 1.1 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 SARAF PF06682.12 CDJ94375.1 - 0.0024 17.6 0.1 0.0031 17.2 0.1 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Protocadherin PF08374.11 CDJ94375.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 Protocadherin CRA PF06589.11 CDJ94375.1 - 0.012 15.7 1.1 0.02 15.0 1.1 1.3 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Connexin PF00029.19 CDJ94375.1 - 0.015 15.0 0.2 0.021 14.6 0.2 1.1 1 0 0 1 1 1 0 Connexin TMEM51 PF15345.6 CDJ94375.1 - 0.018 14.9 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF4834 PF16118.5 CDJ94375.1 - 0.022 15.7 0.0 0.038 15.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) MAP17 PF15807.5 CDJ94375.1 - 0.027 14.7 0.1 0.042 14.1 0.1 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4261 PF14080.6 CDJ94375.1 - 0.053 13.6 0.0 0.09 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4261) EphA2_TM PF14575.6 CDJ94375.1 - 0.067 14.1 0.1 0.14 13.1 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAM209 PF15206.6 CDJ94375.1 - 0.068 13.0 1.9 0.1 12.4 1.0 1.6 2 0 0 2 2 2 0 FAM209 family Ac76 PF05814.11 CDJ94375.1 - 0.07 13.2 0.6 0.12 12.3 0.6 1.4 1 0 0 1 1 1 0 Orf76 (Ac76) TMEM156 PF15106.6 CDJ94375.1 - 0.11 12.0 0.3 0.16 11.4 0.3 1.3 1 0 0 1 1 1 0 TMEM156 protein family PIRT PF15099.6 CDJ94375.1 - 0.3 10.6 0.1 0.3 10.6 0.1 1.9 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family BCIP PF13862.6 CDJ94375.1 - 0.4 10.4 1.5 0.6 9.8 1.5 1.2 1 0 0 1 1 1 0 p21-C-terminal region-binding protein DUF4672 PF15716.5 CDJ94375.1 - 1.5 8.4 7.2 2.4 7.8 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) DUF3464 PF11947.8 CDJ94375.1 - 6.1 6.6 7.1 69 3.2 5.4 2.4 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Ground-like PF04155.18 CDJ94376.1 - 1.3e-09 38.5 0.5 1.8e-09 38.1 0.5 1.1 1 0 0 1 1 1 1 Ground-like domain MGS PF02142.22 CDJ94376.1 - 0.21 11.8 0.0 0.32 11.2 0.0 1.1 1 0 0 1 1 1 0 MGS-like domain CAP PF00188.26 CDJ94377.1 - 2e-43 148.2 11.3 8.9e-20 71.8 0.0 3.2 2 1 1 3 3 3 3 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ94377.1 - 0.93 9.8 13.6 0.14 12.4 1.3 3.3 3 2 0 3 3 3 0 Ancylostoma-associated secreted protein related CAP PF00188.26 CDJ94378.1 - 1.3e-48 165.0 31.5 7.8e-18 65.5 5.2 3.3 3 0 0 3 3 3 3 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ94378.1 - 0.00011 22.4 13.0 0.19 12.0 1.1 4.4 3 2 0 3 3 3 3 Ancylostoma-associated secreted protein related Mucin PF01456.17 CDJ94378.1 - 0.12 12.3 32.5 0.5 10.4 20.8 2.7 2 0 0 2 2 2 0 Mucin-like glycoprotein Ground-like PF04155.18 CDJ94379.1 - 9.4e-13 48.6 1.1 1.2e-12 48.3 1.1 1.1 1 0 0 1 1 1 1 Ground-like domain MGS PF02142.22 CDJ94379.1 - 0.14 12.4 0.0 0.19 11.9 0.0 1.1 1 0 0 1 1 1 0 MGS-like domain TTR-52 PF01060.23 CDJ94380.1 - 9.8e-12 45.4 0.0 1.2e-11 45.1 0.0 1.2 1 0 0 1 1 1 1 Transthyretin-like family TTR-52 PF01060.23 CDJ94381.1 - 3.3e-10 40.5 0.0 3.6e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Transthyretin-like family RRM_1 PF00076.22 CDJ94382.1 - 2.4e-05 24.1 0.0 4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 CDJ94382.1 - 0.0025 17.7 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 RL domain Nucleoporin_C PF03177.14 CDJ94383.1 - 1.1e-09 37.6 11.8 2.8e-09 36.3 11.8 1.6 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 CDJ94383.1 - 0.0017 17.2 0.2 0.0026 16.6 0.2 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Synaptobrevin PF00957.21 CDJ94384.1 - 6.2e-34 115.7 12.2 7.4e-33 112.2 5.0 2.5 2 0 0 2 2 2 2 Synaptobrevin Syntaxin-18_N PF10496.9 CDJ94384.1 - 1.4e-05 25.3 0.1 8.9e-05 22.7 0.0 2.5 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus MCU PF04678.13 CDJ94384.1 - 0.0044 17.1 7.0 0.045 13.9 0.2 3.3 3 0 0 3 3 3 1 Mitochondrial calcium uniporter Laminin_I PF06008.14 CDJ94384.1 - 0.0057 16.4 1.5 0.0057 16.4 1.5 3.1 3 0 0 3 3 3 1 Laminin Domain I DUF773 PF05600.12 CDJ94384.1 - 0.0078 15.0 2.8 0.0078 15.0 2.8 2.2 3 0 0 3 3 3 1 CDK5 regulatory subunit-associated protein 3 LMBR1 PF04791.16 CDJ94384.1 - 0.057 12.3 5.7 0.063 12.2 0.2 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF2207 PF09972.9 CDJ94384.1 - 0.062 12.1 0.3 1 8.0 0.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) PRIMA1 PF16101.5 CDJ94384.1 - 0.076 13.1 0.5 0.2 11.7 0.5 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 XhlA PF10779.9 CDJ94384.1 - 0.28 11.4 8.4 0.67 10.2 0.7 3.4 3 0 0 3 3 3 0 Haemolysin XhlA ASFV_J13L PF05568.11 CDJ94384.1 - 0.43 10.3 2.6 2.1 8.1 0.8 2.5 2 0 0 2 2 2 0 African swine fever virus J13L protein Orf78 PF06024.12 CDJ94384.1 - 0.45 10.8 7.0 1.3 9.4 0.2 3.2 3 0 0 3 3 3 0 Orf78 (ac78) NDT80_PhoG PF05224.12 CDJ94384.1 - 0.51 10.5 3.8 0.3 11.3 0.3 2.0 2 0 0 2 2 2 0 NDT80 / PhoG like DNA-binding family BLOC1_2 PF10046.9 CDJ94384.1 - 0.86 9.9 15.6 0.22 11.9 1.1 3.4 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIVA PF05103.13 CDJ94384.1 - 0.96 9.5 17.2 0.097 12.8 2.8 3.2 3 0 0 3 3 3 0 DivIVA protein Occludin_ELL PF07303.13 CDJ94384.1 - 1.4 9.7 10.7 0.98 10.2 0.4 3.2 3 0 0 3 3 3 0 Occludin homology domain SNARE PF05739.19 CDJ94384.1 - 6.1 6.9 13.3 3.3 7.8 0.2 2.7 2 0 0 2 2 2 0 SNARE domain Fib_alpha PF08702.10 CDJ94384.1 - 10 6.3 16.0 4.8 7.4 0.8 3.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Pkinase PF00069.25 CDJ94385.1 - 3.3e-74 249.6 0.0 5.3e-74 248.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ94385.1 - 2.9e-36 125.1 0.0 4.6e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CDJ94385.1 - 2.1e-16 60.4 0.1 7e-16 58.7 0.0 2.0 2 0 0 2 2 2 1 PH domain Pkinase_C PF00433.24 CDJ94385.1 - 1.6e-09 38.3 3.4 3.9e-09 37.1 3.4 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 CDJ94385.1 - 1.5e-06 27.7 0.0 2.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CDJ94385.1 - 1.4e-05 24.2 0.1 2e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain PH_11 PF15413.6 CDJ94385.1 - 0.022 15.2 1.5 0.49 10.8 1.5 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain FTA2 PF13095.6 CDJ94385.1 - 0.03 14.0 0.4 0.42 10.2 0.1 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SNAP-25 PF00835.19 CDJ94386.1 - 3.7e-22 78.4 1.3 7.8e-22 77.3 1.3 1.6 1 0 0 1 1 1 1 SNAP-25 family V-SNARE_C PF12352.8 CDJ94386.1 - 0.03 14.6 3.6 0.62 10.4 0.0 2.4 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus SNARE PF05739.19 CDJ94386.1 - 0.065 13.2 1.4 26 4.9 0.0 3.3 3 0 0 3 3 3 0 SNARE domain DUF5089 PF17002.5 CDJ94386.1 - 0.25 11.2 9.3 4.5 7.1 9.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5089) DUF16 PF01519.16 CDJ94386.1 - 0.78 10.3 4.7 1.8 9.1 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 Snapin_Pallidin PF14712.6 CDJ94386.1 - 1 9.9 6.0 2 8.9 1.7 2.5 2 1 0 2 2 2 0 Snapin/Pallidin SOAR PF16533.5 CDJ94386.1 - 1.5 8.9 6.3 2.3 8.3 0.0 3.0 3 1 1 4 4 4 0 STIM1 Orai1-activating region TolA_bind_tri PF16331.5 CDJ94386.1 - 2.1 8.5 8.6 0.4 10.8 3.7 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF1664 PF07889.12 CDJ94386.1 - 3.7 7.6 9.5 3 7.9 2.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) RVT_1 PF00078.27 CDJ94387.1 - 8.6e-33 113.7 0.0 1e-32 113.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp PF00026.23 CDJ94388.1 - 2.8e-74 250.4 1.7 3.6e-74 250.0 1.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ94388.1 - 4.7e-12 46.5 6.2 4.7e-12 46.5 6.2 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CDJ94388.1 - 0.0071 17.0 0.0 10 6.8 0.0 3.1 3 0 0 3 3 3 2 Aspartyl protease Lactamase_B_2 PF12706.7 CDJ94389.1 - 0.00012 21.6 0.1 0.00026 20.6 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 CDJ94389.1 - 0.00016 21.8 0.0 0.00037 20.6 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 CDJ94389.1 - 0.027 14.5 0.1 0.043 13.8 0.1 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Tim17 PF02466.19 CDJ94391.1 - 2e-25 89.3 4.9 2.7e-25 88.9 4.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Lactamase_B_2 PF12706.7 CDJ94392.1 - 1.3e-21 77.0 0.0 2.1e-20 73.1 0.2 2.6 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 CDJ94392.1 - 1.3e-08 34.4 0.0 1.9e-07 30.6 0.0 2.4 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.27 CDJ94392.1 - 1.5e-07 31.6 0.1 3.9e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 CDJ94392.1 - 0.018 15.0 0.0 2.5 8.0 0.0 2.3 2 0 0 2 2 2 0 Beta-lactamase superfamily domain DHO_dh PF01180.21 CDJ94392.1 - 0.023 13.9 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase EF_assoc_2 PF08356.12 CDJ94393.1 - 1.2e-31 108.5 0.0 2.6e-31 107.5 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 CDJ94393.1 - 8e-23 79.8 1.3 1.2e-22 79.3 0.3 1.8 2 0 0 2 2 2 1 EF hand associated EF-hand_7 PF13499.6 CDJ94393.1 - 3.7e-09 36.9 0.0 0.00045 20.6 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ94393.1 - 2.3e-07 30.2 0.1 0.013 15.4 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain Ras PF00071.22 CDJ94393.1 - 3.9e-07 29.8 1.0 0.29 10.7 0.0 3.9 4 0 0 4 4 4 3 Ras family EF-hand_1 PF00036.32 CDJ94393.1 - 3.4e-06 26.2 1.2 0.0052 16.3 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_10 PF14788.6 CDJ94393.1 - 0.0082 16.0 0.1 0.0082 16.0 0.1 1.9 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 CDJ94393.1 - 0.0088 16.4 0.0 2.4 8.5 0.0 2.4 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 CDJ94393.1 - 0.014 15.3 0.3 1.9 8.4 0.1 3.3 4 0 0 4 4 4 0 EF-hand domain pair FtsK_SpoIIIE PF01580.18 CDJ94393.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family EF-hand_5 PF13202.6 CDJ94393.1 - 1.9 8.1 3.4 0.96 9.1 0.2 2.3 3 0 0 3 3 3 0 EF hand tRNA_m1G_MT PF01746.21 CDJ94394.1 - 1.7e-29 102.9 0.0 2.9e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Cupin_8 PF13621.6 CDJ94394.1 - 0.048 13.4 0.5 0.075 12.7 0.5 1.3 1 0 0 1 1 1 0 Cupin-like domain Ribosomal_L30_N PF08079.12 CDJ94394.1 - 0.75 10.1 13.3 1.6 9.0 13.3 1.5 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain DUF3020 PF11223.8 CDJ94395.1 - 0.049 14.1 1.6 7.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3020) DUF883 PF05957.13 CDJ94396.1 - 0.0042 17.7 0.0 0.0063 17.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) MutL PF13941.6 CDJ94396.1 - 0.015 13.9 0.3 0.017 13.7 0.3 1.0 1 0 0 1 1 1 0 MutL protein MT0933_antitox PF14013.6 CDJ94396.1 - 0.019 15.3 2.5 0.03 14.6 2.5 1.3 1 0 0 1 1 1 0 MT0933-like antitoxin protein ApoLp-III PF07464.11 CDJ94396.1 - 0.032 14.3 0.2 0.041 14.0 0.2 1.1 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.18 CDJ94397.1 - 9.1e-07 28.9 33.2 0.0094 15.8 1.4 5.5 3 2 2 5 5 5 4 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 CDJ94397.1 - 0.0082 16.2 6.5 36 4.4 0.0 5.7 3 2 4 7 7 7 2 Apolipophorin-III precursor (apoLp-III) TFIIB PF00382.19 CDJ94397.1 - 0.66 10.1 3.9 1.3 9.2 0.3 3.3 2 0 0 2 2 2 0 Transcription factor TFIIB repeat ADH_zinc_N_2 PF13602.6 CDJ94398.1 - 1e-14 55.7 0.0 1.6e-14 55.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDJ94398.1 - 7.6e-11 41.9 0.0 1.4e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDJ94398.1 - 1e-07 32.0 0.1 2.3e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 CDJ94398.1 - 0.074 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AAA PF00004.29 CDJ94399.1 - 3.6e-42 143.9 0.1 8.8e-42 142.7 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CDJ94399.1 - 2.7e-20 72.0 0.2 6.8e-20 70.8 0.2 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CDJ94399.1 - 7.7e-10 38.4 0.4 1.7e-09 37.3 0.4 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CDJ94399.1 - 2e-06 27.8 3.2 4.2e-06 26.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDJ94399.1 - 8.6e-06 26.2 0.3 0.003 18.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CDJ94399.1 - 1.3e-05 25.0 0.1 3.8e-05 23.5 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CDJ94399.1 - 2.6e-05 24.4 0.1 0.00015 22.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDJ94399.1 - 0.00013 22.3 0.2 0.0096 16.2 0.0 2.7 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 CDJ94399.1 - 0.0013 18.0 0.0 0.0022 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 CDJ94399.1 - 0.0016 17.9 0.2 0.0046 16.4 0.1 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CDJ94399.1 - 0.0071 16.9 0.4 0.023 15.2 0.0 2.3 2 2 0 2 2 1 1 AAA domain AAA_7 PF12775.7 CDJ94399.1 - 0.0097 15.4 0.0 0.023 14.2 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region PhoH PF02562.16 CDJ94399.1 - 0.012 15.1 0.1 0.1 12.1 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.6 CDJ94399.1 - 0.012 15.8 0.0 0.037 14.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CDJ94399.1 - 0.016 14.9 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 CDJ94399.1 - 0.017 14.7 0.5 0.1 12.1 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 CDJ94399.1 - 0.018 14.7 0.3 0.05 13.3 0.3 1.8 1 1 0 1 1 1 0 AAA domain TolA_bind_tri PF16331.5 CDJ94399.1 - 0.02 15.0 2.2 0.064 13.3 0.4 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation AAA_11 PF13086.6 CDJ94399.1 - 0.024 14.4 0.4 0.27 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 CDJ94399.1 - 0.032 13.6 0.3 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 KaiC CPT PF07931.12 CDJ94399.1 - 0.043 13.6 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein RNA_helicase PF00910.22 CDJ94399.1 - 0.046 14.1 0.0 0.098 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 CDJ94399.1 - 0.048 12.8 0.0 0.087 12.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain ABC_tran PF00005.27 CDJ94399.1 - 0.063 13.8 0.2 0.6 10.6 0.0 2.4 2 1 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 CDJ94399.1 - 0.065 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain JIP_LZII PF16471.5 CDJ94399.1 - 0.072 13.3 2.5 0.18 12.0 2.5 1.7 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II NACHT PF05729.12 CDJ94399.1 - 0.079 12.9 0.4 0.31 11.0 0.1 2.0 2 0 0 2 2 2 0 NACHT domain AAA_3 PF07726.11 CDJ94399.1 - 0.087 12.7 0.0 0.32 10.9 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CDJ94399.1 - 0.09 12.5 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CDJ94399.1 - 0.1 11.7 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 CDJ94399.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CDJ94399.1 - 0.12 12.7 1.3 0.2 12.0 0.1 2.0 2 1 0 2 2 1 0 AAA domain TsaE PF02367.17 CDJ94399.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mito_carr PF00153.27 CDJ94400.1 - 6.5e-09 35.6 0.0 8.8e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein Hyr1 PF15789.5 CDJ94400.1 - 0.038 13.5 1.3 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Hyphally regulated cell wall GPI-anchored protein 1 NIL PF09383.10 CDJ94401.1 - 0.025 14.4 0.0 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 NIL domain HSP20 PF00011.21 CDJ94402.1 - 1.8e-20 73.0 0.2 2.5e-20 72.5 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ94402.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 0 HSP20-like domain found in ArsA Peptidase_M1 PF01433.20 CDJ94403.1 - 1.1e-40 139.6 0.8 1.2e-40 139.4 0.8 1.0 1 0 0 1 1 1 1 Peptidase family M1 domain EF-hand_7 PF13499.6 CDJ94404.1 - 5.4e-16 58.8 5.6 1.5e-07 31.8 0.7 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ94404.1 - 9.5e-16 56.3 4.1 0.00017 21.3 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 CDJ94404.1 - 1.3e-14 52.6 6.5 0.0035 16.8 0.6 4.5 4 1 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 CDJ94404.1 - 2.1e-12 45.9 10.5 0.0033 16.8 0.8 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CDJ94404.1 - 3.7e-06 26.7 9.6 0.19 11.6 0.0 4.1 5 0 0 5 5 5 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ94404.1 - 0.0038 17.5 1.2 0.6 10.5 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 CDJ94404.1 - 0.071 13.0 1.1 0.43 10.5 0.0 2.8 3 1 1 4 4 4 0 EF hand EF-hand_4 PF12763.7 CDJ94404.1 - 0.084 12.8 3.4 15 5.6 0.0 3.7 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand EB PF01683.18 CDJ94405.1 - 3.1e-14 53.0 54.3 2.6e-10 40.4 8.3 5.6 2 2 3 5 5 5 3 EB module SDA1 PF05285.12 CDJ94406.1 - 7.2e-68 229.6 32.0 7.2e-68 229.6 32.0 2.0 2 0 0 2 2 2 2 SDA1 DcpS_C PF11969.8 CDJ94407.1 - 8.2e-25 87.5 0.3 1.2e-24 87.0 0.3 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 CDJ94407.1 - 1.1e-10 42.1 0.1 3.3e-10 40.6 0.2 1.6 2 0 0 2 2 2 1 HIT domain DUF561 PF04481.12 CDJ94407.1 - 0.24 10.5 0.0 0.32 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF561) Myosin_head PF00063.21 CDJ94408.1 - 8.2e-289 959.6 5.7 8.2e-289 959.6 5.7 3.0 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CDJ94408.1 - 1.1e-147 493.8 270.9 1.5e-147 493.3 270.9 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 CDJ94408.1 - 4.5e-14 52.0 3.8 1.2e-13 50.6 3.8 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.21 CDJ94408.1 - 7.2e-06 25.8 54.6 7.2e-06 25.8 54.6 9.2 1 1 6 7 7 7 2 Intermediate filament protein IQ PF00612.27 CDJ94408.1 - 0.021 14.6 2.6 0.04 13.7 0.1 2.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif BRX_N PF13713.6 CDJ94408.1 - 0.11 12.2 4.8 5.2 6.9 0.0 3.5 3 0 0 3 3 3 0 Transcription factor BRX N-terminal domain AAA_22 PF13401.6 CDJ94408.1 - 0.86 9.9 0.0 0.86 9.9 0.0 6.7 7 3 1 8 8 8 0 AAA domain AAA_19 PF13245.6 CDJ94408.1 - 2.8 8.3 11.5 1.8 8.9 0.0 4.9 3 1 0 3 3 3 0 AAA domain DUF1664 PF07889.12 CDJ94408.1 - 7 6.7 143.0 0.013 15.5 6.3 13.2 2 2 8 13 13 13 0 Protein of unknown function (DUF1664) Mito_carr PF00153.27 CDJ94409.1 - 1.1e-49 166.3 1.8 3.1e-20 71.9 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein FAD_binding_3 PF01494.19 CDJ94409.1 - 2.2e-18 66.7 0.7 1.1e-09 38.0 0.0 2.3 1 1 1 2 2 2 2 FAD binding domain SE PF08491.10 CDJ94409.1 - 0.00017 20.8 0.1 0.00078 18.6 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.14 CDJ94409.1 - 0.018 14.3 0.0 0.39 9.9 0.0 2.2 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CDJ94409.1 - 0.019 13.9 0.0 12 4.6 0.0 3.1 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_8 PF13450.6 CDJ94409.1 - 0.031 14.5 0.1 0.14 12.4 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CDJ94409.1 - 0.054 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase Rdx PF10262.9 CDJ94409.1 - 0.12 12.5 0.0 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 Rdx family Asparaginase_2 PF01112.18 CDJ94410.1 - 2.3e-36 125.4 0.1 3e-36 125.0 0.1 1.1 1 0 0 1 1 1 1 Asparaginase Ribosomal_S2 PF00318.20 CDJ94411.1 - 1.4e-13 50.5 0.0 1.7e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S2 DUF218 PF02698.17 CDJ94411.1 - 0.03 14.3 0.0 0.032 14.3 0.0 1.2 1 0 0 1 1 1 0 DUF218 domain ADH_zinc_N PF00107.26 CDJ94411.1 - 0.12 12.3 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Glyco_trans_2_3 PF13632.6 CDJ94413.1 - 8.4e-42 143.3 1.8 8.4e-42 143.3 1.8 1.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CDJ94413.1 - 1.2e-07 31.9 0.0 1.7e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Fringe PF02434.16 CDJ94413.1 - 0.015 14.7 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 Fringe-like Zona_pellucida PF00100.23 CDJ94414.1 - 5.3e-13 49.4 0.6 6.4e-13 49.1 0.6 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain HGTP_anticodon PF03129.20 CDJ94415.1 - 4.3e-11 42.8 0.0 9.1e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CDJ94415.1 - 4.4e-08 33.3 0.0 8.7e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) EGF_2 PF07974.13 CDJ94416.1 - 0.00011 22.5 25.8 0.027 14.9 2.7 3.6 3 0 0 3 3 3 3 EGF-like domain Laminin_EGF PF00053.24 CDJ94416.1 - 0.026 14.7 22.6 5.2 7.3 5.6 3.5 1 1 2 3 3 3 0 Laminin EGF domain EGF PF00008.27 CDJ94416.1 - 0.46 10.8 0.3 0.46 10.8 0.3 4.1 3 2 0 3 3 3 0 EGF-like domain PCSK9_C3 PF18463.1 CDJ94416.1 - 1.1 9.5 10.8 1.4 9.2 3.7 2.5 1 1 1 2 2 2 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain PBP PF01161.20 CDJ94417.1 - 1.8e-20 73.6 0.1 2.6e-20 73.1 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein zf-HC5HC2H_2 PF13832.6 CDJ94418.1 - 4e-32 110.6 7.5 4e-32 110.6 7.5 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CDJ94418.1 - 1.5e-22 79.6 5.1 1.5e-22 79.6 5.1 3.3 2 1 1 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 CDJ94418.1 - 3.2e-11 42.6 4.7 3.2e-11 42.6 4.7 3.4 4 0 0 4 4 4 1 PHD-finger PHD PF00628.29 CDJ94418.1 - 1.2e-08 34.7 12.0 1.2e-08 34.7 12.0 3.8 3 0 0 3 3 3 2 PHD-finger AT_hook PF02178.19 CDJ94418.1 - 0.024 14.5 5.2 0.088 12.7 5.2 2.1 1 0 0 1 1 1 0 AT hook motif zf-CCCH_4 PF18044.1 CDJ94419.1 - 7.6e-11 41.5 17.1 7.5e-05 22.4 3.3 3.5 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH PF00642.24 CDJ94419.1 - 1.1e-06 28.3 20.1 1.9e-06 27.6 0.9 3.8 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CDJ94419.1 - 6.1e-06 26.9 11.7 0.012 16.3 0.5 3.3 1 1 2 3 3 3 2 Torus domain zf-CCCH_3 PF15663.5 CDJ94419.1 - 3.2e-05 24.1 9.3 0.0085 16.3 3.6 2.3 2 0 0 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 CDJ94419.1 - 0.00037 20.8 21.5 0.016 15.6 4.6 3.3 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 CDJ94419.1 - 0.0047 16.9 4.8 0.0047 16.9 4.8 4.5 4 1 0 4 4 4 2 Zinc finger domain Cnn_1N PF07989.11 CDJ94419.1 - 0.0051 16.9 3.2 0.01 16.0 3.2 1.5 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 bZIP_2 PF07716.15 CDJ94419.1 - 0.036 14.1 3.5 0.036 14.1 3.5 1.9 2 0 0 2 2 2 0 Basic region leucine zipper GIT_CC PF16559.5 CDJ94419.1 - 0.17 11.7 0.2 0.3 11.0 0.2 1.3 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlaC_arch PF05377.11 CDJ94419.1 - 0.26 11.7 1.3 0.42 11.0 1.3 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) CENP-Q PF13094.6 CDJ94419.1 - 0.71 10.1 5.5 1.3 9.2 5.5 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Ras PF00071.22 CDJ94420.1 - 1.5e-54 184.0 0.0 1.8e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ94420.1 - 7.1e-21 74.6 0.0 1.1e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ94420.1 - 7.8e-09 35.2 0.0 1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CDJ94420.1 - 7.7e-07 29.2 0.0 0.0032 17.4 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CDJ94420.1 - 0.00035 20.2 0.0 0.0014 18.2 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CDJ94420.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 CDJ94420.1 - 0.017 14.6 0.0 0.054 13.0 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1 PF01926.23 CDJ94420.1 - 0.019 15.1 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 CDJ94420.1 - 0.045 13.3 0.1 0.12 11.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 CDJ94420.1 - 0.053 13.3 0.4 0.2 11.4 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ATPgrasp_Ter PF15632.6 CDJ94420.1 - 0.073 12.8 0.0 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon Septin PF00735.18 CDJ94420.1 - 0.15 11.3 0.0 3.8 6.7 0.0 2.1 2 0 0 2 2 2 0 Septin RWD PF05773.22 CDJ94421.1 - 8.5e-14 51.8 0.0 1.7e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 CDJ94421.1 - 1.7e-05 25.1 13.1 7e-05 23.1 13.1 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CDJ94421.1 - 0.00028 20.7 7.3 0.0028 17.5 7.6 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ94421.1 - 0.0019 18.1 7.4 0.004 17.1 7.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDJ94421.1 - 0.003 17.6 3.4 0.003 17.6 3.4 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDJ94421.1 - 0.0073 16.1 4.6 0.0073 16.1 4.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CDJ94421.1 - 0.63 9.7 7.5 0.18 11.4 3.7 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CDJ94421.1 - 2.7 7.8 10.2 0.19 11.5 5.1 1.8 2 0 0 2 2 2 0 RING-like zinc finger zf-ANAPC11 PF12861.7 CDJ94421.1 - 2.8 8.1 5.8 10 6.2 5.8 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CDJ94421.1 - 8.2 6.4 13.3 9.3 6.2 0.6 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Tho1_MOS11_C PF18592.1 CDJ94422.1 - 6.4e-08 32.3 12.0 0.00036 20.3 0.1 5.0 4 1 1 5 5 5 4 Tho1/MOS11 C-terminal domain HeH PF12949.7 CDJ94422.1 - 1.8e-07 30.7 0.3 3.4e-07 29.8 0.3 1.5 1 0 0 1 1 1 1 HeH/LEM domain SAP PF02037.27 CDJ94422.1 - 6e-06 25.9 0.2 3.1e-05 23.6 0.2 2.4 1 0 0 1 1 1 1 SAP domain Ish1 PF10281.9 CDJ94422.1 - 0.0007 19.8 0.1 0.0026 18.0 0.1 2.1 2 0 0 2 2 2 1 Putative stress-responsive nuclear envelope protein Endonuc-dimeris PF09124.10 CDJ94422.1 - 0.076 13.2 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 T4 recombination endonuclease VII, dimerisation TLP1_add_C PF18313.1 CDJ94422.1 - 0.1 12.5 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain C5-epim_C PF06662.13 CDJ94423.1 - 3.4e-67 225.6 0.0 8.4e-67 224.3 0.0 1.7 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus XAF1_C PF18608.1 CDJ94423.1 - 0.061 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 XIAP-associated factor 1 C-terminal domain Prenyltrans PF00432.21 CDJ94423.1 - 0.11 12.3 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat Glycos_transf_2 PF00535.26 CDJ94424.1 - 2e-25 89.6 0.0 3.3e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CDJ94424.1 - 3e-17 63.0 2.0 4.9e-17 62.4 2.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 CDJ94424.1 - 4.8e-07 30.4 0.1 2.7e-05 24.8 0.0 2.5 1 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Glyco_transf_7C PF02709.14 CDJ94424.1 - 8.9e-06 25.3 0.2 2.1e-05 24.1 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CDJ94424.1 - 4e-05 23.2 0.0 7.9e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 ATP_synth_reg PF14960.6 CDJ94424.1 - 0.21 11.1 0.1 0.38 10.3 0.1 1.4 1 0 0 1 1 1 0 ATP synthase regulation Kinesin PF00225.23 CDJ94425.1 - 8.2e-106 353.7 0.9 1e-105 353.4 0.9 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ94425.1 - 4.7e-24 85.0 0.1 1e-23 83.9 0.1 1.5 1 0 0 1 1 1 1 Microtubule binding DUF4094 PF13334.6 CDJ94425.1 - 0.034 14.6 3.0 0.034 14.6 0.2 2.4 3 0 0 3 3 2 0 Domain of unknown function (DUF4094) Spc7 PF08317.11 CDJ94425.1 - 0.045 12.6 6.3 0.03 13.2 3.6 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 CDJ94425.1 - 0.046 14.3 1.6 0.046 14.3 1.6 2.0 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Pox_A_type_inc PF04508.12 CDJ94425.1 - 0.13 12.1 1.5 0.5 10.3 0.0 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat I_LWEQ PF01608.17 CDJ94425.1 - 0.15 12.3 3.6 3.1 8.0 0.0 2.4 2 0 0 2 2 2 0 I/LWEQ domain Rootletin PF15035.6 CDJ94425.1 - 0.35 10.9 3.7 0.17 11.9 1.1 1.7 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion ADIP PF11559.8 CDJ94425.1 - 0.68 10.0 7.8 0.69 10.0 3.0 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Cnn_1N PF07989.11 CDJ94425.1 - 1.8 8.8 10.2 7.2 6.8 0.1 3.0 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 YscO PF07321.12 CDJ94425.1 - 2.6 8.0 7.6 0.74 9.8 3.6 2.1 2 1 0 2 2 2 0 Type III secretion protein YscO DivIC PF04977.15 CDJ94425.1 - 6.9 6.5 5.8 7.4 6.4 1.4 2.8 1 1 1 2 2 2 0 Septum formation initiator HTH_Tnp_Tc3_2 PF01498.18 CDJ94426.1 - 2.9e-24 85.1 1.3 6.5e-24 84.0 1.3 1.6 1 0 0 1 1 1 1 Transposase PAX PF00292.18 CDJ94426.1 - 9e-05 22.4 0.3 0.00013 21.9 0.3 1.2 1 0 0 1 1 1 1 'Paired box' domain HTH_32 PF13565.6 CDJ94426.1 - 0.00017 22.1 9.2 0.00056 20.5 0.5 3.0 1 1 2 3 3 3 1 Homeodomain-like domain HTH_24 PF13412.6 CDJ94426.1 - 0.0025 17.4 2.9 0.26 10.9 0.2 3.4 4 0 0 4 4 4 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 CDJ94426.1 - 0.017 15.0 0.1 0.52 10.2 0.0 2.4 1 1 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 CDJ94426.1 - 0.021 14.7 0.8 5.9 6.9 0.6 2.8 2 1 0 2 2 2 0 MarR family HTH_23 PF13384.6 CDJ94426.1 - 0.024 14.4 0.1 0.024 14.4 0.1 3.4 4 0 0 4 4 4 0 Homeodomain-like domain HTH_28 PF13518.6 CDJ94426.1 - 0.036 14.2 0.6 0.25 11.5 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Rrf2 PF02082.20 CDJ94426.1 - 0.074 13.4 0.0 2.8 8.3 0.0 2.2 1 1 1 2 2 2 0 Transcriptional regulator PIF1 PF05970.14 CDJ94427.1 - 2.6e-67 227.5 0.0 3.1e-67 227.3 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.14 CDJ94427.1 - 1.6e-06 26.4 0.0 2.2e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 CDJ94427.1 - 1.4e-05 24.8 0.0 3.3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 CDJ94427.1 - 0.0057 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 CDJ94427.1 - 0.099 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Lectin_C PF00059.21 CDJ94428.1 - 8.1e-10 39.4 1.0 9.8e-09 35.9 0.0 2.6 2 1 0 2 2 2 1 Lectin C-type domain Mucin PF01456.17 CDJ94428.1 - 0.65 10.0 32.4 1.1 9.2 32.4 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Astacin PF01400.24 CDJ94429.1 - 2.2e-11 43.7 0.0 2.5e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Neuropeptide_S PF14993.6 CDJ94429.1 - 0.17 11.7 1.0 0.21 11.4 0.2 1.6 2 0 0 2 2 2 0 Neuropeptide S precursor protein Astacin PF01400.24 CDJ94430.1 - 3.9e-53 179.9 0.8 4.8e-53 179.6 0.8 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) ShK PF01549.24 CDJ94430.1 - 1.4e-08 35.1 6.6 2.5e-08 34.3 6.6 1.4 1 0 0 1 1 1 1 ShK domain-like CAP_N PF01213.19 CDJ94430.1 - 0.006 16.1 2.6 0.0086 15.6 2.6 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 CDJ94430.1 - 1.6 8.7 5.9 2.3 8.3 5.9 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator RRM_1 PF00076.22 CDJ94431.1 - 4e-13 49.0 0.0 8.9e-06 25.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAP_GLY PF01302.25 CDJ94432.1 - 2.1e-17 62.9 2.6 4.5e-17 61.8 2.6 1.6 1 0 0 1 1 1 1 CAP-Gly domain Acetyltransf_1 PF00583.25 CDJ94432.1 - 5.7e-14 52.4 0.0 2.3e-13 50.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family MgtE PF01769.16 CDJ94432.1 - 9.9e-14 51.8 0.1 1.8e-13 50.9 0.1 1.4 1 0 0 1 1 1 1 Divalent cation transporter LRR_4 PF12799.7 CDJ94432.1 - 2.9e-12 46.6 6.9 0.0018 18.7 0.1 4.8 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDJ94432.1 - 5.5e-08 32.5 0.0 0.0016 18.0 0.0 2.4 2 0 0 2 2 2 2 Leucine-rich repeat Acetyltransf_7 PF13508.7 CDJ94432.1 - 5.6e-08 33.1 0.0 1.4e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDJ94432.1 - 8.5e-08 32.2 0.1 1.7e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain LRR_8 PF13855.6 CDJ94432.1 - 8.5e-06 25.4 2.4 0.43 10.4 0.0 4.8 4 2 2 6 6 6 3 Leucine rich repeat FR47 PF08445.10 CDJ94432.1 - 3.7e-05 23.6 0.0 8.5e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein LRR_6 PF13516.6 CDJ94432.1 - 0.00036 20.3 1.3 1.1 9.5 0.2 4.5 4 0 0 4 4 4 1 Leucine Rich repeat Acetyltransf_15 PF17013.5 CDJ94432.1 - 0.012 15.1 0.3 0.023 14.1 0.3 1.5 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_3 PF13302.7 CDJ94432.1 - 0.039 14.6 0.0 0.095 13.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CDJ94432.1 - 0.15 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 CDJ94432.1 - 0.15 12.0 0.9 0.26 11.3 0.1 1.7 2 0 0 2 2 1 0 ESCO1/2 acetyl-transferase Cyclin_N PF00134.23 CDJ94433.1 - 1.6e-09 37.5 0.0 2.1e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain WD40 PF00400.32 CDJ94434.1 - 1.8e-17 63.4 13.8 0.012 16.5 0.2 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ94434.1 - 0.0021 18.3 8.0 0.25 11.7 1.3 3.7 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain V_ATPase_I PF01496.19 CDJ94435.1 - 3.4e-296 984.5 2.3 3.8e-296 984.3 2.3 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family SNF2_N PF00176.23 CDJ94436.1 - 2.5e-56 190.9 0.7 4.3e-56 190.1 0.7 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ94436.1 - 3.7e-21 75.5 0.3 2.8e-18 66.3 0.0 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ94436.1 - 3.7e-11 43.3 0.1 1.2e-10 41.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CDJ94436.1 - 1.1e-05 24.7 0.0 2.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CENP-P PF13096.6 CDJ94436.1 - 0.0024 17.6 0.2 1.4 8.6 0.1 2.5 2 0 0 2 2 2 2 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P HHH_3 PF12836.7 CDJ94436.1 - 0.0076 16.5 0.1 0.031 14.5 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif MOLO1 PF17175.4 CDJ94437.1 - 5e-07 29.9 0.3 1.1e-06 28.7 0.3 1.6 1 1 0 1 1 1 1 Modulator of levamisole receptor-1 Tweety PF04906.13 CDJ94437.1 - 0.07 11.8 0.8 0.11 11.2 0.8 1.2 1 0 0 1 1 1 0 Tweety ddrB-ParB PF18763.1 CDJ94438.1 - 0.077 13.1 0.3 0.67 10.1 0.2 2.1 2 0 0 2 2 2 0 ddrB-like ParB superfamily domain PTB PF08416.13 CDJ94439.1 - 1.3e-26 93.3 0.0 2e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH2 PF00017.24 CDJ94439.1 - 2.6e-11 43.4 0.0 4.8e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 SH2 domain PID_2 PF14719.6 CDJ94439.1 - 0.012 15.5 0.1 0.031 14.1 0.1 1.7 1 1 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.23 CDJ94439.1 - 0.017 15.2 0.1 0.034 14.2 0.1 1.5 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) Abhydrolase_4 PF08386.10 CDJ94439.1 - 0.034 14.2 0.1 0.066 13.3 0.1 1.4 1 0 0 1 1 1 0 TAP-like protein Big_1 PF02369.16 CDJ94439.1 - 0.07 13.1 0.7 0.18 11.9 0.5 1.8 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) Invasin_D3 PF09134.10 CDJ94439.1 - 0.12 12.6 0.1 0.34 11.2 0.1 1.7 1 0 0 1 1 1 0 Invasin, domain 3 PTEN_C2 PF10409.9 CDJ94440.1 - 6.2e-07 29.2 0.0 1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 CDJ94440.1 - 0.039 13.8 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain CTP_transf_like PF01467.26 CDJ94441.1 - 7.5e-30 104.0 0.0 1.3e-29 103.2 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like Mito_carr PF00153.27 CDJ94442.1 - 3.4e-11 42.9 0.0 4.2e-06 26.6 0.0 2.6 3 0 0 3 3 3 2 Mitochondrial carrier protein eIF3_subunit PF08597.10 CDJ94443.1 - 7e-21 75.2 8.5 1.8e-20 73.9 8.5 1.6 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit Amino_oxidase PF01593.24 CDJ94444.1 - 2e-88 297.7 0.0 2.9e-88 297.2 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 CDJ94444.1 - 3e-15 56.3 0.0 1.1e-14 54.6 0.0 2.0 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.6 CDJ94444.1 - 1.8e-11 44.1 0.2 4.1e-11 43.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CDJ94444.1 - 5.8e-05 22.5 0.6 0.00024 20.4 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ94444.1 - 0.00022 20.1 0.3 0.00043 19.1 0.3 1.5 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 CDJ94444.1 - 0.0003 20.1 0.0 0.00066 19.0 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 CDJ94444.1 - 0.0048 16.2 0.2 0.021 14.1 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CDJ94444.1 - 0.015 14.6 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 CDJ94444.1 - 0.017 14.7 0.1 0.035 13.7 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 CDJ94444.1 - 0.018 15.6 1.0 0.23 12.0 0.1 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CDJ94444.1 - 0.027 14.5 0.1 0.29 11.1 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 CDJ94444.1 - 0.029 13.4 0.1 0.049 12.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 CDJ94444.1 - 0.065 12.6 2.0 0.078 12.3 0.4 1.9 2 1 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 CDJ94444.1 - 0.067 12.4 0.1 0.18 11.0 0.1 1.7 1 0 0 1 1 1 0 Thi4 family DUF87 PF01935.17 CDJ94444.1 - 0.097 12.7 2.2 9.7 6.2 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain 2-Hacid_dh_C PF02826.19 CDJ94444.1 - 0.11 11.8 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 CDJ94444.1 - 0.11 11.5 0.4 0.29 10.2 0.4 1.7 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 CDJ94444.1 - 0.21 10.6 0.6 0.42 9.6 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein MRP-S26 PF14943.6 CDJ94444.1 - 1.3 9.0 7.0 0.1 12.5 1.5 1.9 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 DDE_Tnp_1_7 PF13843.6 CDJ94448.1 - 9.1e-13 48.2 0.1 9.7e-13 48.1 0.1 1.0 1 0 0 1 1 1 1 Transposase IS4 Neur_chan_LBD PF02931.23 CDJ94449.1 - 2.9e-47 160.9 7.3 3.5e-47 160.6 7.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ94449.1 - 3.6e-23 82.9 7.5 4.7e-20 72.7 1.0 2.3 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region TTR-52 PF01060.23 CDJ94450.1 - 1.2e-13 51.5 0.0 2.2e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Transthyretin-like family APG17 PF04108.12 CDJ94451.1 - 0.00033 19.9 19.3 0.00033 19.9 19.3 3.9 2 2 1 3 3 3 2 Autophagy protein Apg17 Alanine_zipper PF11839.8 CDJ94451.1 - 0.026 14.9 10.5 0.026 14.9 10.5 8.6 5 3 2 7 7 7 0 Alanine-zipper, major outer membrane lipoprotein Nore1-SARAH PF16517.5 CDJ94451.1 - 0.1 12.5 4.3 1.2 9.1 0.7 2.9 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Glyco_hydro_4 PF02056.16 CDJ94451.1 - 2.5 7.6 6.8 1.2 8.7 1.4 2.7 2 1 0 2 2 2 0 Family 4 glycosyl hydrolase DUF148 PF02520.17 CDJ94453.1 - 7.4e-05 22.8 0.1 9.5e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF148 LIM PF00412.22 CDJ94454.1 - 2.1e-10 40.7 10.3 7.7e-10 38.9 7.2 2.0 2 0 0 2 2 2 1 LIM domain NCD3G PF07562.14 CDJ94454.1 - 0.0054 16.7 6.1 0.0054 16.7 6.1 1.9 1 1 1 2 2 2 2 Nine Cysteines Domain of family 3 GPCR DUF1272 PF06906.11 CDJ94454.1 - 0.044 13.9 7.4 0.061 13.4 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) c-SKI_SMAD_bind PF08782.10 CDJ94454.1 - 0.3 11.4 6.1 0.5 10.6 6.1 1.4 1 1 0 1 1 1 0 c-SKI Smad4 binding domain DinB_2 PF12867.7 CDJ94456.1 - 0.3 11.6 3.1 0.2 12.2 0.3 2.0 2 0 0 2 2 2 0 DinB superfamily Exo_endo_phos_2 PF14529.6 CDJ94457.1 - 0.17 11.7 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ94457.1 - 0.18 11.3 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Astacin PF01400.24 CDJ94458.1 - 8.4e-66 221.2 0.0 1.5e-65 220.4 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB PF00431.20 CDJ94458.1 - 3.4e-05 24.1 0.1 6.4e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 CUB domain Reprolysin_4 PF13583.6 CDJ94458.1 - 0.0012 18.6 1.0 0.012 15.2 0.5 2.1 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 CDJ94458.1 - 0.024 13.6 0.6 0.04 12.9 0.6 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M57 PF12388.8 CDJ94458.1 - 0.052 13.2 0.0 0.095 12.3 0.0 1.5 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.24 CDJ94458.1 - 0.073 12.9 0.9 0.34 10.7 0.9 1.9 1 1 0 1 1 1 0 Matrixin Sec23_trunk PF04811.15 CDJ94460.1 - 5.4e-17 62.2 0.1 6.8e-17 61.8 0.1 1.1 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 CDJ94460.1 - 6.8e-16 58.0 5.8 1.2e-15 57.3 5.8 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 CDJ94460.1 - 0.0066 15.8 0.1 0.016 14.6 0.1 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Prok-RING_4 PF14447.6 CDJ94460.1 - 0.3 11.0 3.5 0.64 9.9 3.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Calx-beta PF03160.14 CDJ94462.1 - 1.2e-50 169.8 5.7 1.8e-24 85.8 0.4 2.7 2 0 0 2 2 2 2 Calx-beta domain Na_Ca_ex PF01699.24 CDJ94462.1 - 3.4e-48 163.4 34.8 1.1e-25 90.4 11.6 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Na_Ca_ex_C PF16494.5 CDJ94462.1 - 7.2e-24 84.7 2.9 1.4e-23 83.7 2.9 1.4 1 0 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain ZYG-11_interact PF05884.12 CDJ94464.1 - 3e-47 161.4 3.4 3.4e-47 161.3 3.4 1.0 1 0 0 1 1 1 1 Interactor of ZYG-11 TBCA PF02970.16 CDJ94464.1 - 0.053 13.9 0.4 0.12 12.7 0.4 1.5 1 0 0 1 1 1 0 Tubulin binding cofactor A ZYG-11_interact PF05884.12 CDJ94465.1 - 3.4e-24 85.8 7.3 4.1e-24 85.5 7.3 1.0 1 0 0 1 1 1 1 Interactor of ZYG-11 Bax1-I PF01027.20 CDJ94465.1 - 0.00018 21.4 7.0 0.0002 21.2 7.0 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 FUSC PF04632.12 CDJ94465.1 - 1 7.8 4.7 1.3 7.4 4.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CD36 PF01130.21 CDJ94467.1 - 3.7e-25 88.4 0.8 4.3e-25 88.2 0.8 1.0 1 0 0 1 1 1 1 CD36 family Reprolysin PF01421.19 CDJ94468.1 - 3.4e-32 112.0 0.2 1.1e-31 110.3 0.1 2.0 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 CDJ94468.1 - 2.9e-22 79.4 0.4 1.7e-21 76.9 0.0 2.2 2 0 0 2 2 2 1 Reprolysin family propeptide ADAM_CR PF08516.12 CDJ94468.1 - 1.5e-20 73.7 13.6 1.5e-20 73.7 13.6 3.5 3 0 0 3 3 3 1 ADAM cysteine-rich Disintegrin PF00200.23 CDJ94468.1 - 7.4e-17 61.9 30.6 7.4e-17 61.9 30.6 4.6 3 1 0 3 3 3 1 Disintegrin Reprolysin_4 PF13583.6 CDJ94468.1 - 5.3e-07 29.5 1.7 2.3e-06 27.4 1.7 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.13 CDJ94468.1 - 7.6e-05 23.0 8.8 7.6e-05 23.0 8.8 6.1 5 1 1 6 6 6 1 EGF-like domain Reprolysin_2 PF13574.6 CDJ94468.1 - 0.0054 16.6 0.2 0.012 15.5 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 CDJ94468.1 - 0.0064 17.0 0.0 0.021 15.3 0.0 2.0 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like SKG6 PF08693.10 CDJ94468.1 - 0.28 10.6 3.7 0.55 9.7 3.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain COX5A PF02284.16 CDJ94469.1 - 1.2e-41 140.9 0.0 1.7e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Methyltransf_25 PF13649.6 CDJ94470.1 - 3.4e-08 34.1 0.0 6.5e-06 26.8 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CDJ94470.1 - 5.6e-07 29.2 0.0 1.4e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 CDJ94470.1 - 0.0014 19.2 0.0 0.01 16.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ94470.1 - 0.0062 16.4 0.0 0.033 14.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 CDJ94470.1 - 0.0064 16.4 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain SsgA PF04686.12 CDJ94470.1 - 0.0081 16.1 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 Streptomyces sporulation and cell division protein, SsgA MTS PF05175.14 CDJ94470.1 - 0.0094 15.5 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 CDJ94470.1 - 0.057 12.5 1.7 1.8 7.6 0.0 2.7 3 0 0 3 3 3 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 CDJ94470.1 - 0.11 12.5 0.8 0.55 10.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Presenilin PF01080.17 CDJ94470.1 - 1.8 7.3 3.8 2.7 6.7 3.8 1.2 1 0 0 1 1 1 0 Presenilin Ank_2 PF12796.7 CDJ94471.1 - 2.1e-14 53.9 0.2 1.3e-12 48.1 0.0 2.9 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ94471.1 - 2.8e-13 49.8 0.0 2e-06 28.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDJ94471.1 - 9.6e-12 45.2 0.1 2e-08 34.6 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ94471.1 - 4.9e-11 41.8 0.3 6e-05 23.1 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CDJ94471.1 - 5.5e-10 39.2 1.1 0.00012 22.3 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat zf-MYND PF01753.18 CDJ94471.1 - 1.2e-05 25.3 16.9 2.5e-05 24.3 16.9 1.6 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 CDJ94471.1 - 0.00024 20.9 14.6 0.00052 19.8 14.6 1.6 1 0 0 1 1 1 1 HIT zinc finger HEPN_Toprim_N PF18871.1 CDJ94472.1 - 0.0012 18.8 1.0 0.0016 18.4 1.0 1.2 1 0 0 1 1 1 1 HEPN/Toprim N-terminal domain 1 Fez1 PF06818.15 CDJ94472.1 - 0.0039 17.7 14.4 0.0052 17.3 14.0 1.4 1 1 0 1 1 1 1 Fez1 Nmad5 PF18757.1 CDJ94472.1 - 0.031 14.5 3.2 0.04 14.1 3.2 1.2 1 0 0 1 1 1 0 Nucleotide modification associated domain 5 YabA PF06156.13 CDJ94472.1 - 0.54 10.9 17.4 2.7 8.7 1.8 2.8 2 1 0 2 2 2 0 Initiation control protein YabA Spc7 PF08317.11 CDJ94472.1 - 0.61 8.9 15.3 1.3 7.8 6.5 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein CENP-H PF05837.12 CDJ94472.1 - 1.1 9.8 13.6 0.16 12.4 7.0 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) NBD_C PF17042.5 CDJ94472.1 - 2.2 8.8 4.7 15 6.0 0.8 2.1 2 0 0 2 2 2 0 Nucleotide-binding C-terminal domain DUF16 PF01519.16 CDJ94472.1 - 2.2 8.8 17.9 2 8.9 4.0 2.4 1 1 0 2 2 2 0 Protein of unknown function DUF16 DHR10 PF18595.1 CDJ94472.1 - 2.8 8.0 21.4 1.1 9.4 13.1 2.7 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain Atg14 PF10186.9 CDJ94472.1 - 2.8 6.9 13.8 0.49 9.4 6.4 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3450 PF11932.8 CDJ94472.1 - 3 7.1 14.1 0.29 10.4 6.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) CDC37_N PF03234.14 CDJ94472.1 - 3.4 8.6 13.3 0.11 13.4 3.4 2.2 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding Fib_alpha PF08702.10 CDJ94472.1 - 5.5 7.2 14.2 7.1 6.8 4.6 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family NAM-associated PF14303.6 CDJ94472.1 - 6.6 7.4 9.1 0.48 11.1 3.6 1.7 1 1 1 2 2 2 0 No apical meristem-associated C-terminal domain Na_Ca_ex PF01699.24 CDJ94473.1 - 6.3e-46 156.1 36.4 6.1e-25 87.9 9.6 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Anoctamin PF04547.12 CDJ94474.1 - 4.5e-109 365.3 20.7 6.3e-109 364.8 20.7 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 CDJ94474.1 - 7.7e-20 71.6 0.2 7.9e-19 68.3 0.2 2.5 1 1 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin AF-4 PF05110.13 CDJ94475.1 - 1.4e-12 46.7 16.5 1.4e-12 46.7 16.5 2.6 1 1 0 2 2 2 1 AF-4 proto-oncoprotein DUF5128 PF17170.4 CDJ94475.1 - 0.0064 15.7 0.3 0.011 14.9 0.3 1.3 1 0 0 1 1 1 1 6-bladed beta-propeller Apyrase PF06079.11 CDJ94476.1 - 1.4e-101 339.6 0.2 1.7e-101 339.3 0.2 1.0 1 0 0 1 1 1 1 Apyrase Trehalose_PPase PF02358.16 CDJ94476.1 - 0.05 12.7 0.1 0.073 12.2 0.1 1.2 1 0 0 1 1 1 0 Trehalose-phosphatase GIY-YIG PF01541.24 CDJ94476.1 - 0.091 13.0 0.2 0.2 12.0 0.2 1.5 1 0 0 1 1 1 0 GIY-YIG catalytic domain DUF5386 PF17360.2 CDJ94478.1 - 1.1e-19 71.0 0.2 1.8e-11 44.3 0.3 2.1 1 1 1 2 2 2 2 Family of unknown function (DUF5386) ANF_receptor PF01094.28 CDJ94479.1 - 5.9e-37 127.6 0.1 7.2e-37 127.3 0.1 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 CDJ94479.1 - 0.011 15.4 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein Succ_CoA_lig PF13607.6 CDJ94479.1 - 0.07 12.9 0.1 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain MeaB PF03308.16 CDJ94480.1 - 5.6e-22 78.0 0.0 6.8e-22 77.7 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 CDJ94480.1 - 0.01 15.4 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Thymidylate_kin PF02223.17 CDJ94480.1 - 0.026 14.2 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 Thymidylate kinase RNA_helicase PF00910.22 CDJ94480.1 - 0.027 14.8 0.0 0.035 14.5 0.0 1.3 1 0 0 1 1 1 0 RNA helicase DUF87 PF01935.17 CDJ94480.1 - 0.086 12.9 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain ATP_bind_1 PF03029.17 CDJ94480.1 - 0.093 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Guanylate_cyc PF00211.20 CDJ94482.1 - 1.5e-60 204.0 0.0 2e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 CDJ94482.1 - 2.3e-05 24.0 0.8 2.3e-05 24.0 0.8 1.8 2 0 0 2 2 2 1 Heme NO binding associated dsDNA_bind PF01984.20 CDJ94482.1 - 0.00096 19.4 1.4 0.0026 18.0 0.0 2.0 2 0 0 2 2 2 1 Double-stranded DNA-binding domain Corona_6B_7B PF03262.13 CDJ94482.1 - 0.17 11.3 0.0 0.41 10.1 0.0 1.4 1 1 0 1 1 1 0 Coronavirus 6B/7B protein HTH_48 PF17906.1 CDJ94484.1 - 5.5e-15 55.2 0.1 2.1e-14 53.4 0.0 1.9 2 0 0 2 2 2 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 CDJ94484.1 - 0.00036 21.1 0.1 0.00082 19.9 0.1 1.8 1 1 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 CDJ94484.1 - 0.00062 19.5 0.5 0.42 10.5 0.1 2.8 3 0 0 3 3 3 2 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 CDJ94484.1 - 0.0013 18.9 0.1 0.0023 18.1 0.1 1.4 1 0 0 1 1 1 1 Transposase HTH_11 PF08279.12 CDJ94484.1 - 0.0028 17.6 0.1 0.0051 16.7 0.1 1.3 1 0 0 1 1 1 1 HTH domain HTH_29 PF13551.6 CDJ94484.1 - 0.0028 17.6 0.0 0.036 14.1 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Mga PF08280.11 CDJ94484.1 - 0.0033 17.4 0.1 0.0063 16.5 0.1 1.4 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain HTH_24 PF13412.6 CDJ94484.1 - 0.014 14.9 0.3 0.033 13.8 0.3 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Phage_CI_repr PF07022.13 CDJ94484.1 - 0.014 15.4 0.3 0.21 11.7 0.0 2.4 2 1 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain HTH_AsnC-type PF13404.6 CDJ94484.1 - 0.043 13.7 0.1 0.096 12.5 0.1 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_28 PF13518.6 CDJ94484.1 - 0.13 12.4 1.9 0.29 11.3 0.4 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_10 PF04967.12 CDJ94484.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain LisH PF08513.11 CDJ94485.1 - 7.9e-06 25.6 0.3 1.9e-05 24.4 0.3 1.7 1 0 0 1 1 1 1 LisH Neur_chan_memb PF02932.16 CDJ94485.1 - 2.6 8.0 5.9 3.9 7.5 5.9 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 CDJ94485.1 - 3.2 6.5 5.1 3.7 6.3 5.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2052 PF09747.9 CDJ94485.1 - 3.7 7.6 13.6 6.3 6.9 13.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) 7TM_GPCR_Srt PF10321.9 CDJ94486.1 - 2.9e-29 102.1 7.2 3.3e-29 101.9 7.2 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt BAMBI PF06211.12 CDJ94487.1 - 3.1 8.1 10.9 0.57 10.5 4.9 2.3 1 1 0 2 2 2 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Trehalose_PPase PF02358.16 CDJ94488.1 - 0.079 12.1 0.0 4.8 6.2 0.0 2.2 2 0 0 2 2 2 0 Trehalose-phosphatase DUF3338 PF11819.8 CDJ94488.1 - 0.096 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) PTH2 PF01981.16 CDJ94489.1 - 7e-21 74.7 0.0 8.3e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 RexA PF15969.5 CDJ94489.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Intracellular sensor of Lambda phage, Abi component LMWPc PF01451.21 CDJ94490.1 - 2.7e-38 131.5 0.0 3.2e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DUF1474 PF07342.11 CDJ94490.1 - 0.01 16.4 0.0 0.016 15.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1474) ICL PF00463.21 CDJ94490.1 - 0.11 11.0 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Isocitrate lyase family Ribosomal_L35p PF01632.19 CDJ94491.1 - 1.9e-07 31.5 0.0 3.9e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L35 Hydrolase_4 PF12146.8 CDJ94492.1 - 6.5e-08 32.1 0.0 7.9e-05 22.0 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ94492.1 - 3.1e-07 30.3 0.0 0.00067 19.4 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 CDJ94492.1 - 2.6e-06 27.4 0.0 0.08 12.7 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 CDJ94492.1 - 5e-06 27.3 0.2 0.00094 19.8 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CDJ94492.1 - 0.0004 19.9 0.0 0.00086 18.8 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF1057 PF06342.12 CDJ94492.1 - 0.00097 18.3 0.7 0.013 14.6 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) Asp2 PF16929.5 CDJ94492.1 - 0.058 12.4 0.0 0.092 11.7 0.0 1.2 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter Tombus_P33 PF08500.10 CDJ94492.1 - 0.08 12.9 2.1 2 8.4 0.3 2.3 2 0 0 2 2 2 0 Tombusvirus p33 Ser_hydrolase PF06821.13 CDJ94492.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase LRR_8 PF13855.6 CDJ94493.1 - 7.2e-43 144.2 28.1 2.2e-13 49.8 0.8 6.1 2 1 6 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 CDJ94493.1 - 6e-18 64.7 28.8 7.9e-07 29.3 0.1 7.2 6 2 2 8 8 8 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CDJ94493.1 - 1.9e-14 53.7 0.0 3.5e-06 27.0 0.0 2.9 1 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 CDJ94493.1 - 2.6e-10 39.4 12.5 0.27 11.9 0.0 8.5 10 0 0 10 10 10 4 Leucine Rich Repeat LRR_9 PF14580.6 CDJ94493.1 - 1.1e-06 28.3 5.8 0.0033 17.0 2.2 2.9 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 CDJ94493.1 - 3.7 7.9 30.7 9.2 6.6 0.0 7.4 8 0 0 8 8 8 0 Leucine Rich repeat DUF148 PF02520.17 CDJ94494.1 - 5.7e-18 65.0 11.2 8.2e-18 64.5 11.2 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF148 7TMR-HDED PF07697.11 CDJ94494.1 - 0.016 15.3 2.9 0.023 14.8 2.9 1.2 1 0 0 1 1 1 0 7TM-HD extracellular Sigma70_ner PF04546.13 CDJ94494.1 - 0.024 14.5 6.2 0.039 13.8 6.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Prominin PF05478.11 CDJ94494.1 - 0.082 10.9 4.0 0.1 10.6 4.0 1.1 1 0 0 1 1 1 0 Prominin NFRKB_winged PF14465.6 CDJ94494.1 - 0.085 13.1 2.9 0.26 11.5 1.1 2.0 1 1 1 2 2 2 0 NFRKB Winged Helix-like FAA_hydrolase_N PF09298.11 CDJ94494.1 - 0.13 12.5 2.0 0.12 12.6 0.5 1.8 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal ColG_sub PF18496.1 CDJ94494.1 - 0.17 12.1 7.0 0.058 13.6 3.0 2.0 1 1 1 2 2 2 0 Collagenase G catalytic helper subdomain Zwint PF15556.6 CDJ94494.1 - 0.18 11.3 6.2 0.24 10.9 6.2 1.3 1 0 0 1 1 1 0 ZW10 interactor DUF16 PF01519.16 CDJ94494.1 - 0.32 11.5 8.7 0.16 12.4 5.7 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 BLOC1_2 PF10046.9 CDJ94494.1 - 0.58 10.5 8.4 0.45 10.9 6.3 1.9 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.22 CDJ94494.1 - 0.94 9.7 11.5 0.2 11.9 7.6 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4298 PF14131.6 CDJ94494.1 - 6.3 6.8 10.8 0.87 9.6 3.3 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4298) DUF148 PF02520.17 CDJ94495.1 - 1.7e-31 108.5 9.9 2e-31 108.3 9.9 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF148 DegS PF05384.11 CDJ94495.1 - 7.6e-05 22.3 6.5 9.6e-05 21.9 6.5 1.2 1 0 0 1 1 1 1 Sensor protein DegS Apolipoprotein PF01442.18 CDJ94495.1 - 0.0065 16.4 2.5 0.0098 15.8 2.5 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Prominin PF05478.11 CDJ94495.1 - 0.022 12.7 2.3 0.025 12.5 2.3 1.2 1 0 0 1 1 1 0 Prominin DUF3502 PF12010.8 CDJ94495.1 - 0.023 15.4 2.5 0.032 14.9 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3502) DUF4004 PF13171.6 CDJ94495.1 - 0.038 14.2 2.6 0.047 13.9 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4004) Mit_ribos_Mrp51 PF11709.8 CDJ94495.1 - 0.06 12.9 3.5 0.069 12.7 3.5 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit GLE1 PF07817.13 CDJ94495.1 - 0.067 12.4 4.7 0.53 9.4 1.9 2.2 1 1 1 2 2 2 0 GLE1-like protein Cauli_AT PF03233.13 CDJ94495.1 - 0.07 13.1 7.0 1.5 8.8 0.2 2.1 1 1 1 2 2 2 0 Aphid transmission protein HSP70 PF00012.20 CDJ94495.1 - 0.17 10.1 7.6 0.21 9.8 7.6 1.0 1 0 0 1 1 1 0 Hsp70 protein ACR_tran PF00873.19 CDJ94495.1 - 0.27 8.8 1.4 0.32 8.6 1.4 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family ApoLp-III PF07464.11 CDJ94495.1 - 0.27 11.3 8.9 0.84 9.7 8.9 1.7 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) KLRAQ PF10205.9 CDJ94495.1 - 0.62 10.3 8.3 1.1 9.6 8.3 1.4 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein DUF1664 PF07889.12 CDJ94495.1 - 0.73 9.9 4.5 0.41 10.7 2.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Glyco_transf_8 PF01501.20 CDJ94496.1 - 1.7e-13 50.7 2.0 1.1e-05 25.1 0.1 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 8 Exo_endo_phos PF03372.23 CDJ94498.1 - 1.4e-18 67.2 0.0 2.6e-18 66.4 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 CDJ94498.1 - 9.1e-13 47.8 13.4 1.4e-10 40.8 6.6 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CDJ94498.1 - 5.6e-10 39.3 6.5 1.4e-06 28.5 1.0 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDJ94498.1 - 0.099 12.1 0.3 0.2 11.1 0.3 1.5 1 0 0 1 1 1 0 Leucine-rich repeat LRR_1 PF00560.33 CDJ94498.1 - 0.58 10.9 8.4 17 6.5 0.1 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat Sec23_trunk PF04811.15 CDJ94499.1 - 1.6e-65 221.1 0.0 2.4e-65 220.5 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CDJ94499.1 - 1.4e-19 70.6 0.0 2.8e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CDJ94499.1 - 1.9e-18 66.2 0.0 4.8e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CDJ94499.1 - 2.8e-12 46.4 6.0 7.3e-12 45.1 6.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CDJ94499.1 - 0.0074 16.2 0.1 0.037 13.9 0.0 2.0 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 CDJ94499.1 - 0.29 10.6 1.2 0.69 9.3 1.2 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain BING4CT PF08149.11 CDJ94500.1 - 2.5e-32 110.5 0.0 9.2e-32 108.7 0.0 2.1 1 0 0 1 1 1 1 BING4CT (NUC141) domain WD40 PF00400.32 CDJ94500.1 - 6.9e-07 29.9 0.1 0.0022 18.8 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ94500.1 - 2.5e-05 24.5 0.1 3.2 8.1 0.1 4.3 2 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CDJ94500.1 - 0.00017 20.8 0.0 0.00027 20.1 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40_like PF17005.5 CDJ94500.1 - 0.0058 16.0 0.0 0.059 12.7 0.0 2.1 2 0 0 2 2 2 1 WD40-like domain ComGG PF14173.6 CDJ94500.1 - 0.069 13.6 0.1 0.16 12.4 0.1 1.5 1 0 0 1 1 1 0 ComG operon protein 7 UDPGT PF00201.18 CDJ94501.1 - 5.4e-60 203.6 0.0 6.6e-60 203.3 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ94501.1 - 7.1e-07 29.4 0.0 1.2e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.6 CDJ94501.1 - 0.014 15.8 0.0 0.024 15.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Innexin PF00876.18 CDJ94502.1 - 1.3e-100 337.1 11.6 1.7e-100 336.7 11.6 1.1 1 0 0 1 1 1 1 Innexin Ribosomal_S25 PF03297.15 CDJ94503.1 - 3.7e-41 139.4 4.7 5.7e-41 138.8 4.7 1.4 1 1 0 1 1 1 1 S25 ribosomal protein Fe_dep_repress PF01325.19 CDJ94503.1 - 0.006 16.8 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.19 CDJ94503.1 - 0.04 13.8 0.6 0.06 13.2 0.2 1.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 CDJ94503.1 - 0.15 12.0 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 MarR family Nckap1 PF09735.9 CDJ94504.1 - 0 1306.2 20.5 0 1301.9 20.5 2.0 1 1 0 1 1 1 1 Membrane-associated apoptosis protein V-set PF07686.17 CDJ94504.1 - 0.00034 20.8 0.0 0.00085 19.5 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 CDJ94504.1 - 0.0024 18.4 0.1 0.0059 17.2 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CDJ94504.1 - 0.0055 17.0 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 CDJ94504.1 - 0.027 14.6 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin I-set domain ig PF00047.25 CDJ94504.1 - 0.028 14.6 0.1 0.067 13.4 0.1 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Ntox17 PF15524.6 CDJ94504.1 - 0.059 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Novel toxin 17 SH3_9 PF14604.6 CDJ94506.1 - 2.3e-18 65.8 0.0 2.2e-14 53.0 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 CDJ94506.1 - 2.7e-15 55.7 0.0 1.4e-10 40.6 0.0 2.8 3 0 0 3 3 3 2 SH3 domain SH3_2 PF07653.17 CDJ94506.1 - 1.8e-11 43.6 0.0 1.9e-10 40.3 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain Sorb PF02208.16 CDJ94506.1 - 0.0011 18.7 0.3 0.0025 17.6 0.3 1.6 1 0 0 1 1 1 1 Sorbin homologous domain Bac_small_YrzI PF09501.10 CDJ94506.1 - 0.5 10.5 1.9 1.1 9.4 1.9 1.5 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) HTH_48 PF17906.1 CDJ94507.1 - 4.3e-17 62.0 0.1 7.9e-17 61.1 0.1 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase Transposase_1 PF01359.18 CDJ94507.1 - 2.5e-10 40.1 0.0 4.2e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 CDJ94507.1 - 0.00095 18.9 0.1 0.0014 18.4 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Adap_comp_sub PF00928.21 CDJ94509.1 - 0.01 15.2 0.1 0.013 14.9 0.1 1.2 1 0 0 1 1 1 0 Adaptor complexes medium subunit family Helicase_C PF00271.31 CDJ94510.1 - 2.3e-21 76.2 0.0 8.9e-18 64.7 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ94510.1 - 1.2e-17 64.2 0.0 2.2e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase RQC PF09382.10 CDJ94510.1 - 2.9e-14 52.8 0.0 8.5e-14 51.3 0.0 1.8 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 CDJ94510.1 - 2.6e-12 46.5 0.0 5.9e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 HRDC domain RecQ_Zn_bind PF16124.5 CDJ94510.1 - 7.4e-07 29.8 1.9 1e-06 29.4 0.7 1.9 2 0 0 2 2 2 1 RecQ zinc-binding HTH_40 PF14493.6 CDJ94510.1 - 4.1e-05 24.0 0.0 9.8e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain ResIII PF04851.15 CDJ94510.1 - 0.01 15.8 0.0 0.024 14.7 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Carboxyl_trans PF01039.22 CDJ94511.1 - 2.5e-155 517.9 0.0 3.8e-155 517.3 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 CDJ94511.1 - 0.0091 15.5 0.4 0.16 11.4 0.0 2.3 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) Ribonuclease_3 PF00636.26 CDJ94511.1 - 0.025 15.2 0.1 0.15 12.7 0.1 2.2 1 1 0 1 1 1 0 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CDJ94511.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease-III-like Cyclin_N PF00134.23 CDJ94512.1 - 6.5e-47 158.4 0.5 6.5e-47 158.4 0.5 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CDJ94512.1 - 3.2e-20 72.4 0.0 5.3e-19 68.5 0.0 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N2 PF16500.5 CDJ94512.1 - 0.02 15.6 0.4 0.037 14.8 0.4 1.4 1 0 0 1 1 1 0 N-terminal region of cyclin_N Thiolase_N PF00108.23 CDJ94513.1 - 1.6e-88 296.5 0.4 2.5e-88 295.8 0.4 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CDJ94513.1 - 1.5e-52 176.4 1.2 7.2e-52 174.2 0.3 2.4 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CDJ94513.1 - 2.1e-05 24.2 0.1 0.00013 21.6 0.1 2.3 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 CDJ94513.1 - 0.054 13.7 0.1 0.66 10.2 0.0 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 CDJ94513.1 - 0.08 12.8 1.2 3.4 7.6 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Lon_C PF05362.13 CDJ94514.1 - 3.3e-58 196.6 0.0 5.5e-58 195.9 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 CDJ94514.1 - 7.9e-22 78.1 0.0 2.6e-21 76.4 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CS PF04969.16 CDJ94514.1 - 4.8e-17 62.7 0.4 1.4e-16 61.2 0.4 1.9 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 CDJ94514.1 - 8.8e-11 41.6 0.1 2.5e-10 40.2 0.1 1.8 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. ChlI PF13541.6 CDJ94514.1 - 1.2e-07 31.5 0.0 3.2e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 CDJ94514.1 - 3.6e-07 30.3 0.0 9.6e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CDJ94514.1 - 0.00021 21.1 0.0 0.0011 18.8 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 CDJ94514.1 - 0.00023 21.0 0.0 0.00047 20.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ94514.1 - 0.00039 20.8 1.8 0.00083 19.8 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CDJ94514.1 - 0.00042 20.6 0.0 0.12 12.6 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CDJ94514.1 - 0.0022 18.1 0.0 0.006 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 CDJ94514.1 - 0.01 15.1 0.9 0.023 13.9 0.1 2.0 2 0 0 2 2 2 0 TIP49 P-loop domain IstB_IS21 PF01695.17 CDJ94514.1 - 0.012 15.4 1.0 0.026 14.3 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 CDJ94514.1 - 0.016 15.8 0.0 0.073 13.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CDJ94514.1 - 0.026 13.9 0.0 0.76 9.1 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 CDJ94514.1 - 0.03 14.2 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 CDJ94514.1 - 0.036 13.2 0.0 0.076 12.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 CDJ94514.1 - 0.041 14.0 1.4 0.11 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CDJ94514.1 - 0.051 14.0 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 CDJ94514.1 - 0.094 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CDJ94514.1 - 0.16 11.8 0.1 1 9.3 0.0 2.2 2 1 0 2 2 2 0 NACHT domain AAA_11 PF13086.6 CDJ94514.1 - 9.3 6.0 10.4 13 5.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain RVT_1 PF00078.27 CDJ94515.1 - 9.1e-05 22.1 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 2OG-FeII_Oxy_3 PF13640.6 CDJ94517.1 - 2.5e-20 73.2 0.0 4.9e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 CDJ94517.1 - 1.4e-10 41.7 0.0 2.8e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pneumo_att_G PF05539.11 CDJ94517.1 - 3.5 7.1 10.4 6.5 6.2 10.4 1.4 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G SUI1 PF01253.22 CDJ94519.1 - 8.3e-16 58.3 0.7 1.8e-15 57.2 0.1 1.8 2 0 0 2 2 2 1 Translation initiation factor SUI1 HAD_2 PF13419.6 CDJ94519.1 - 0.0055 16.8 0.1 0.0084 16.2 0.1 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NotI PF12183.8 CDJ94519.1 - 0.017 14.5 0.1 0.019 14.3 0.1 1.2 1 0 0 1 1 1 0 Restriction endonuclease NotI 4HBT PF03061.22 CDJ94520.1 - 6.1e-15 55.3 0.3 9.8e-15 54.7 0.3 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 CDJ94520.1 - 1.3e-05 25.6 0.2 1.7e-05 25.2 0.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.6 CDJ94520.1 - 0.027 14.6 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Phytochelatin PF05023.14 CDJ94522.1 - 6e-42 143.3 0.0 7.4e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_M28 PF04389.17 CDJ94523.1 - 6e-42 143.6 0.0 1e-41 142.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CDJ94523.1 - 1.4e-05 24.9 0.0 2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 CDJ94523.1 - 0.039 13.0 0.0 0.066 12.2 0.0 1.3 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase LUC7 PF03194.15 CDJ94524.1 - 1.5e-56 191.9 6.1 2.3e-56 191.3 6.1 1.3 1 0 0 1 1 1 1 LUC7 N_terminus GIT1_C PF12205.8 CDJ94524.1 - 0.023 14.8 0.4 0.045 13.9 0.4 1.4 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term ABC_tran_CTD PF16326.5 CDJ94524.1 - 0.56 10.5 4.7 1.3 9.4 0.6 2.6 3 0 0 3 3 3 0 ABC transporter C-terminal domain TPR_19 PF14559.6 CDJ94526.1 - 2.7e-20 72.6 0.0 1.1e-07 32.2 0.1 5.5 4 1 1 5 5 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ94526.1 - 1.1e-15 57.6 9.8 5.1e-06 26.6 0.1 5.6 4 2 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CDJ94526.1 - 2.6e-11 42.7 14.9 0.089 13.0 0.0 7.6 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ94526.1 - 7.8e-09 35.0 20.0 0.067 13.1 0.0 8.1 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ94526.1 - 9.3e-09 35.5 1.9 2.1 8.7 0.0 6.4 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ94526.1 - 1e-07 32.1 7.5 0.6 10.9 0.0 6.3 6 0 0 6 6 5 2 Tetratricopeptide repeat PPR_2 PF13041.6 CDJ94526.1 - 1.1e-06 28.7 0.1 0.00057 20.0 0.0 4.3 4 0 0 4 4 4 1 PPR repeat family TPR_14 PF13428.6 CDJ94526.1 - 4.1e-06 27.2 0.0 3.6 8.7 0.0 6.5 6 1 1 7 7 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ94526.1 - 4.6e-06 26.3 1.3 0.035 14.1 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CDJ94526.1 - 4.2e-05 23.6 2.5 0.029 14.4 2.3 3.7 2 1 1 3 3 3 1 Putative TPR-like repeat TPR_3 PF07720.12 CDJ94526.1 - 0.00025 20.9 5.9 1.5 8.9 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat PPR PF01535.20 CDJ94526.1 - 0.00063 19.8 10.6 0.0014 18.7 0.1 5.6 6 0 0 6 6 5 1 PPR repeat TPR_16 PF13432.6 CDJ94526.1 - 0.00098 19.7 0.0 4.3 8.1 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat DUF627 PF04781.12 CDJ94526.1 - 0.0052 16.8 0.2 2 8.4 0.0 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF627) TPR_9 PF13371.6 CDJ94526.1 - 0.012 15.8 0.0 0.35 11.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_3 PF13812.6 CDJ94526.1 - 0.021 14.9 0.0 0.061 13.4 0.0 1.8 1 0 0 1 1 1 0 Pentatricopeptide repeat domain HrpB1_HrpK PF09613.10 CDJ94526.1 - 0.047 13.3 0.1 7.2 6.3 0.1 3.5 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Metallophos_3 PF14582.6 CDJ94526.1 - 0.079 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Coatomer_E PF04733.14 CDJ94526.1 - 0.11 11.9 2.5 2.7 7.3 0.6 2.9 3 0 0 3 3 3 0 Coatomer epsilon subunit TPR_8 PF13181.6 CDJ94526.1 - 0.11 12.7 8.5 5.4 7.5 0.0 6.2 8 0 0 8 8 8 0 Tetratricopeptide repeat Collagen PF01391.18 CDJ94527.1 - 1.1e-16 60.3 114.6 0.17 11.7 56.2 4.7 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ94527.1 - 1.3e-16 60.4 1.4 1.7e-16 60.0 1.4 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Col_cuticle_N PF01484.17 CDJ94528.1 - 9.4e-20 70.4 2.2 1.2e-19 70.0 2.2 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ94528.1 - 1.5e-10 40.7 117.1 8.2e-08 31.9 28.4 5.3 2 2 2 4 4 4 3 Collagen triple helix repeat (20 copies) LRR19-TM PF15176.6 CDJ94528.1 - 0.17 11.9 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain TDP43_N PF18694.1 CDJ94529.1 - 2e-19 69.2 0.0 5e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain Exo_endo_phos_2 PF14529.6 CDJ94529.1 - 3.2e-06 27.0 0.0 9.3e-06 25.5 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Vps52 PF04129.12 CDJ94529.1 - 0.018 13.8 10.5 0.015 14.1 0.8 2.7 2 1 1 3 3 3 0 Vps52 / Sac2 family Tetraspanin PF00335.20 CDJ94529.1 - 0.25 11.0 0.1 0.5 10.0 0.1 1.4 1 0 0 1 1 1 0 Tetraspanin family DivIC PF04977.15 CDJ94529.1 - 0.29 10.9 0.0 0.29 10.9 0.0 6.3 5 1 1 6 6 6 0 Septum formation initiator DUF3629 PF12302.8 CDJ94529.1 - 6.8 6.1 9.4 0.23 10.9 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3629) 14-3-3 PF00244.20 CDJ94531.1 - 3.3e-110 366.8 5.6 3.8e-110 366.7 5.6 1.0 1 0 0 1 1 1 1 14-3-3 protein PhoU_div PF01865.16 CDJ94531.1 - 0.0041 16.5 0.3 0.028 13.8 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF47 Peptidase_C98 PF15499.6 CDJ94531.1 - 0.0062 16.0 0.1 0.011 15.2 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase AAA_15 PF13175.6 CDJ94531.1 - 0.082 12.6 1.3 0.12 12.1 1.3 1.3 1 0 0 1 1 1 0 AAA ATPase domain DUF4710 PF15828.5 CDJ94531.1 - 2 8.6 7.8 11 6.2 1.7 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4710) Virulence_fact PF13769.6 CDJ94531.1 - 2 8.7 5.7 1.1 9.5 0.6 2.9 2 1 1 3 3 3 0 Virulence factor fn3 PF00041.21 CDJ94532.1 - 1.2e-07 31.9 0.0 3.1e-07 30.6 0.0 1.6 2 0 0 2 2 2 1 Fibronectin type III domain Baculo_F PF12259.8 CDJ94532.1 - 0.04 12.4 0.1 0.043 12.3 0.1 1.1 1 0 0 1 1 1 0 Baculovirus F protein HTH_48 PF17906.1 CDJ94534.1 - 1.5e-06 28.2 0.2 2.4e-06 27.5 0.2 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_50 PF18024.1 CDJ94534.1 - 0.00015 21.3 0.0 0.00028 20.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AsnC-type PF13404.6 CDJ94534.1 - 0.12 12.3 1.0 3 7.7 0.1 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Guanylate_cyc PF00211.20 CDJ94535.1 - 9.3e-54 181.8 0.0 1.1e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 CDJ94536.1 - 1.5e-26 93.4 0.1 1.9e-26 93.0 0.1 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 CDJ94537.1 - 1.4e-16 60.6 0.0 2.1e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ94537.1 - 3.2e-11 43.1 0.0 5.2e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ANF_receptor PF01094.28 CDJ94537.1 - 0.0019 17.4 0.1 0.0045 16.2 0.0 1.6 2 0 0 2 2 2 1 Receptor family ligand binding region DUF3180 PF11377.8 CDJ94537.1 - 0.011 15.9 1.2 0.021 14.9 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) DUF1616 PF07760.11 CDJ94537.1 - 0.14 11.5 0.4 0.21 10.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Cadherin_C_2 PF16492.5 CDJ94537.1 - 0.16 12.7 0.2 0.31 11.8 0.2 1.4 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal RVT_1 PF00078.27 CDJ94538.1 - 3.7e-26 92.0 0.0 7.4e-18 64.9 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3629 PF12302.8 CDJ94538.1 - 0.043 13.2 0.2 0.097 12.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) ScdA_N PF04405.14 CDJ94539.1 - 0.007 16.0 0.0 6.9 6.4 0.0 2.7 2 0 0 2 2 2 2 Domain of Unknown function (DUF542) ZZ PF00569.17 CDJ94539.1 - 0.38 10.6 2.8 22 5.0 0.2 2.7 2 0 0 2 2 2 0 Zinc finger, ZZ type BTK PF00779.19 CDJ94539.1 - 4 7.3 14.9 3.6 7.5 1.8 3.0 3 0 0 3 3 3 0 BTK motif Guanylate_cyc PF00211.20 CDJ94540.1 - 1.2e-66 223.9 0.0 1.6e-66 223.5 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 CDJ94540.1 - 2.5e-07 30.4 0.9 3.4e-07 29.9 0.9 1.2 1 0 0 1 1 1 1 Heme NO binding associated RE_ApaLI PF09499.10 CDJ94540.1 - 0.04 13.6 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease ISPD_C PF18706.1 CDJ94540.1 - 0.075 12.7 0.2 0.11 12.1 0.2 1.2 1 0 0 1 1 1 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain Exo_endo_phos_2 PF14529.6 CDJ94541.1 - 0.0026 17.6 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ94541.1 - 0.036 13.6 0.0 0.067 12.7 0.0 1.4 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 CDJ94542.1 - 3.7e-06 26.6 0.0 6.7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CDJ94543.1 - 3.7e-06 26.6 0.0 6.7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CDJ94546.1 - 8.2e-05 22.2 0.0 8.9e-05 22.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Collagen PF01391.18 CDJ94547.1 - 6e-19 67.6 117.0 5.7e-07 29.2 39.1 3.7 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ94547.1 - 4.6e-08 33.0 0.1 6.5e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain BAR_3_WASP_bdg PF10456.9 CDJ94548.1 - 3.8e-53 180.4 0.5 7.1e-53 179.5 0.3 1.5 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein PX PF00787.24 CDJ94548.1 - 1.9e-21 76.2 0.2 4e-21 75.1 0.2 1.5 1 0 0 1 1 1 1 PX domain BTB PF00651.31 CDJ94549.1 - 0.026 14.8 0.1 0.12 12.6 0.1 2.0 2 0 0 2 2 2 0 BTB/POZ domain DUF4770 PF15994.5 CDJ94549.1 - 0.076 13.3 1.1 1.1 9.4 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) DUF3614 PF12267.8 CDJ94549.1 - 1.2 9.6 6.0 10 6.6 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3614) LRR_8 PF13855.6 CDJ94550.1 - 2.2e-20 72.2 10.2 9e-08 31.8 0.3 5.3 1 1 4 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 CDJ94550.1 - 1.2e-11 44.6 6.0 0.013 15.9 0.1 5.2 3 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CDJ94550.1 - 3.8e-08 33.4 0.1 4.5e-07 29.9 0.0 2.2 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 CDJ94550.1 - 5.8e-05 23.1 10.1 1.3 9.9 0.0 6.9 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.6 CDJ94550.1 - 3.9 7.8 12.2 4.6 7.5 0.0 5.4 6 0 0 6 6 6 0 Leucine Rich repeat Aldo_ket_red PF00248.21 CDJ94551.1 - 3.8e-44 151.1 0.0 4.5e-38 131.1 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Myosin_head PF00063.21 CDJ94553.1 - 7.7e-276 916.7 3.6 7.7e-276 916.7 3.6 1.9 2 1 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CDJ94553.1 - 9.7e-14 50.2 83.2 1.4e-13 49.6 83.2 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 CDJ94553.1 - 9.6e-07 28.5 0.3 2.2e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.6 CDJ94553.1 - 0.046 14.0 0.0 0.28 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain IQ PF00612.27 CDJ94553.1 - 0.14 12.0 4.6 0.054 13.3 0.9 2.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_22 PF13401.6 CDJ94553.1 - 0.43 10.9 0.0 0.43 10.9 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CDJ94553.1 - 0.93 9.9 0.0 0.93 9.9 0.0 4.1 3 2 0 3 3 3 0 AAA ATPase domain TDP43_N PF18694.1 CDJ94554.1 - 1.2e-24 85.9 0.0 2.2e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain RRM_1 PF00076.22 CDJ94554.1 - 3.9e-18 65.0 2.0 2.8e-08 33.5 0.2 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ94554.1 - 0.052 13.7 0.3 0.72 10.0 0.1 2.5 2 0 0 2 2 2 0 RNA recognition motif RRM_3 PF08777.11 CDJ94554.1 - 0.18 11.9 0.3 17 5.6 0.1 2.9 2 1 1 3 3 3 0 RNA binding motif p450 PF00067.22 CDJ94556.1 - 4.8e-69 233.3 0.0 5.1e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LRR_9 PF14580.6 CDJ94558.1 - 7.5e-74 247.0 3.5 9.7e-74 246.6 3.5 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CDJ94558.1 - 3.5e-10 40.0 19.3 4.9e-06 26.8 2.3 3.2 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ94558.1 - 1.2e-08 34.5 2.3 4e-08 32.9 0.5 2.5 2 1 0 2 2 2 1 Leucine rich repeat CHASE3 PF05227.13 CDJ94558.1 - 0.27 11.1 3.3 4.4 7.2 0.7 2.5 3 0 0 3 3 3 0 CHASE3 domain DUF778 PF05608.12 CDJ94559.1 - 5.7e-39 134.4 1.4 1e-19 71.6 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF778) Ins_beta PF03488.14 CDJ94560.1 - 0.00089 19.2 10.3 0.055 13.5 5.1 2.2 1 1 1 2 2 2 2 Nematode insulin-related peptide beta type Insulin PF00049.18 CDJ94560.1 - 0.0076 17.2 10.1 0.084 13.9 8.8 2.5 2 1 0 2 2 2 1 Insulin/IGF/Relaxin family COesterase PF00135.28 CDJ94562.1 - 2.9e-105 353.1 0.0 3.3e-105 352.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDJ94562.1 - 4.2e-08 33.3 0.0 8.4e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Collagen PF01391.18 CDJ94563.1 - 1.1e-24 86.0 94.1 1.1e-09 38.0 30.6 4.1 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) AA_permease_2 PF13520.6 CDJ94564.1 - 3.7e-40 138.0 41.0 3.7e-40 138.0 41.0 2.2 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 CDJ94564.1 - 3e-34 118.4 35.8 3e-34 118.4 35.8 2.1 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 CDJ94564.1 - 7.5e-21 74.0 12.4 7.5e-21 74.0 12.4 3.1 2 0 0 2 2 2 1 C-terminus of AA_permease HA2 PF04408.23 CDJ94565.1 - 1.4e-20 73.6 0.0 1.4e-20 73.6 0.0 3.3 3 1 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDJ94565.1 - 2e-19 69.7 0.1 4.7e-19 68.5 0.1 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDJ94565.1 - 1.8e-11 44.3 0.0 6.1e-11 42.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ94565.1 - 3.1e-05 23.8 0.0 6.6e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 CDJ94565.1 - 7.7e-05 21.9 0.0 0.00021 20.5 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 CDJ94565.1 - 0.0031 17.8 0.0 0.0031 17.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CDJ94565.1 - 0.0087 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Reprolysin PF01421.19 CDJ94565.1 - 0.023 14.6 0.0 0.057 13.3 0.0 1.6 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease PWI PF01480.17 CDJ94565.1 - 0.052 13.9 0.3 0.5 10.7 0.0 2.7 3 0 0 3 3 3 0 PWI domain PhoH PF02562.16 CDJ94565.1 - 0.11 11.9 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.6 CDJ94565.1 - 0.44 11.0 0.0 0.44 11.0 0.0 3.6 2 1 0 2 2 1 0 AAA domain Med5 PF08689.10 CDJ94565.1 - 2.9 5.6 7.6 4.3 5.0 7.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit Med5 C9orf72-like PF15019.6 CDJ94566.1 - 4e-42 144.5 0.0 5.5e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 C9orf72-like protein family Guanylate_cyc PF00211.20 CDJ94567.1 - 8.6e-60 201.5 0.0 1.8e-59 200.4 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 CDJ94567.1 - 1.2e-37 129.9 0.2 1.8e-37 129.3 0.2 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 CDJ94567.1 - 5.2e-21 75.1 0.0 1.8e-20 73.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ94567.1 - 4.7e-19 68.8 0.0 1.4e-18 67.3 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Peripla_BP_6 PF13458.6 CDJ94567.1 - 0.0031 17.2 0.0 0.0051 16.5 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein HNOBA PF07701.14 CDJ94567.1 - 0.032 13.7 0.2 0.056 12.9 0.2 1.4 1 0 0 1 1 1 0 Heme NO binding associated Glyoxal_oxid_N PF07250.11 CDJ94567.1 - 0.082 12.1 0.1 0.25 10.5 0.0 1.7 2 0 0 2 2 2 0 Glyoxal oxidase N-terminus CRCB PF02537.15 CDJ94567.1 - 0.14 12.5 0.5 0.42 11.0 0.0 2.0 2 0 0 2 2 2 0 CrcB-like protein, Camphor Resistance (CrcB) Apolipoprotein PF01442.18 CDJ94568.1 - 0.018 14.9 2.9 0.59 10.0 0.1 2.0 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain YtxH PF12732.7 CDJ94568.1 - 0.068 13.7 13.5 0.16 12.6 3.4 3.1 1 1 1 2 2 2 0 YtxH-like protein Chlorosome_CsmC PF11098.8 CDJ94568.1 - 0.17 11.8 4.9 0.081 12.9 1.1 2.1 1 1 1 2 2 2 0 Chlorosome envelope protein C DUF883 PF05957.13 CDJ94568.1 - 0.29 11.8 6.9 5 7.8 0.4 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) ATP-synt_B PF00430.18 CDJ94568.1 - 0.52 10.4 5.2 17 5.5 0.0 2.6 1 1 2 3 3 3 0 ATP synthase B/B' CF(0) TauD PF02668.16 CDJ94570.1 - 2e-41 142.5 0.0 2.7e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 CDJ94570.1 - 4.3e-05 24.1 0.0 0.00067 20.3 0.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF971) DUF2442 PF10387.9 CDJ94570.1 - 0.013 15.8 0.1 1.4 9.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2442) CsiD PF08943.10 CDJ94570.1 - 0.022 13.9 0.0 0.082 12.0 0.0 1.9 2 0 0 2 2 2 0 CsiD RRM_5 PF13893.6 CDJ94571.1 - 3.2e-43 146.3 0.9 7e-30 103.2 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CDJ94571.1 - 3.6e-23 81.2 0.3 9.2e-08 31.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 CDJ94571.1 - 3.7e-13 49.5 0.3 2e-12 47.1 0.0 2.3 3 0 0 3 3 3 1 RRM-like domain RRM_occluded PF16842.5 CDJ94571.1 - 3e-05 23.8 0.0 0.021 14.6 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif Biopterin_H PF00351.21 CDJ94572.1 - 2.4e-129 431.1 0.4 3.6e-129 430.6 0.4 1.3 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ThiP_synth PF10120.9 CDJ94572.1 - 0.076 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Thiamine-phosphate synthase IF3_N PF05198.16 CDJ94572.1 - 0.084 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain GDI PF00996.18 CDJ94573.1 - 4.1e-51 173.9 0.0 1.6e-36 125.8 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor UCH PF00443.29 CDJ94573.1 - 2.9e-32 112.2 0.0 4.4e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ94573.1 - 4e-10 39.8 0.0 1.8e-09 37.7 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase NAD_binding_8 PF13450.6 CDJ94573.1 - 0.0083 16.3 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HAT_KAT11 PF08214.11 CDJ94575.1 - 2.4e-57 194.8 1.5 4.7e-57 193.9 1.5 1.5 1 0 0 1 1 1 1 Histone acetylation protein KIX PF02172.16 CDJ94575.1 - 8.9e-37 125.2 1.2 1.9e-36 124.2 1.2 1.6 1 0 0 1 1 1 1 KIX domain zf-TAZ PF02135.16 CDJ94575.1 - 1.1e-26 93.1 70.4 2.2e-19 69.7 16.5 3.8 3 0 0 3 3 3 2 TAZ zinc finger DUF902 PF06001.13 CDJ94575.1 - 8.5e-18 64.6 4.6 8.5e-18 64.6 4.6 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF902) ZZ PF00569.17 CDJ94575.1 - 6.4e-09 35.5 10.7 6.4e-09 35.5 10.7 3.9 5 0 0 5 5 5 1 Zinc finger, ZZ type KIX_2 PF16987.5 CDJ94575.1 - 4.9e-06 26.5 0.2 2e-05 24.5 0.2 2.2 1 0 0 1 1 1 1 KIX domain HTH_Tnp_Tc3_2 PF01498.18 CDJ94577.1 - 4.7e-24 84.4 0.3 8.5e-24 83.6 0.3 1.4 1 0 0 1 1 1 1 Transposase PAX PF00292.18 CDJ94577.1 - 4.9e-05 23.3 0.1 0.00012 22.0 0.1 1.7 2 0 0 2 2 2 1 'Paired box' domain DDE_3 PF13358.6 CDJ94577.1 - 0.00078 19.2 0.0 0.0016 18.2 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 CDJ94577.1 - 0.0043 17.6 5.7 0.028 15.0 0.1 2.6 1 1 2 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.6 CDJ94577.1 - 0.042 13.6 0.2 0.042 13.6 0.2 2.5 3 0 0 3 3 3 0 Homeodomain-like domain HTH_24 PF13412.6 CDJ94577.1 - 0.062 12.9 0.5 1.3 8.6 0.0 2.7 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding Metallophos PF00149.28 CDJ94579.1 - 0.14 12.6 0.0 0.26 11.8 0.0 1.4 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase HPD PF05044.12 CDJ94580.1 - 1.5e-77 258.8 2.8 2.2e-77 258.2 2.8 1.3 1 0 0 1 1 1 1 Homeo-prospero domain PI3K_1B_p101 PF10486.9 CDJ94580.1 - 0.58 7.9 5.4 0.75 7.5 5.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PTB PF08416.13 CDJ94581.1 - 1.7e-18 67.0 0.0 3.3e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH3_2 PF07653.17 CDJ94581.1 - 1.8e-10 40.3 0.0 4.5e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDJ94581.1 - 2.7e-08 33.3 0.0 5.3e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CDJ94581.1 - 1e-06 28.5 0.0 2.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 CDJ94581.1 - 0.0035 17.7 0.0 0.0077 16.6 0.0 1.5 1 0 0 1 1 1 1 Helically-extended SH3 domain Caskin-Pro-rich PF16907.5 CDJ94581.1 - 0.069 13.7 0.0 0.069 13.7 0.0 2.4 3 0 0 3 3 3 0 Proline rich region of Caskin proteins SH3_3 PF08239.11 CDJ94581.1 - 0.069 13.4 0.2 0.13 12.6 0.2 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain ASC PF00858.24 CDJ94582.1 - 1.3e-62 212.2 0.6 1.1e-30 107.1 0.0 2.1 1 1 1 2 2 2 2 Amiloride-sensitive sodium channel WBP-1 PF11669.8 CDJ94582.1 - 0.0071 17.0 1.6 0.077 13.6 0.0 2.7 3 0 0 3 3 3 1 WW domain-binding protein 1 Mtp PF03821.16 CDJ94583.1 - 0.0005 19.7 13.3 0.021 14.4 0.2 2.5 1 1 1 2 2 2 2 Golgi 4-transmembrane spanning transporter DUF996 PF06195.13 CDJ94583.1 - 0.0052 17.1 26.4 0.0094 16.2 15.3 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF996) CytochromB561_N PF09786.9 CDJ94583.1 - 0.0074 15.3 1.9 0.024 13.7 1.7 1.8 1 1 0 1 1 1 1 Cytochrome B561, N terminal DUF4728 PF15860.5 CDJ94583.1 - 0.029 15.1 23.6 0.16 12.7 7.8 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4728) DUF3139 PF11337.8 CDJ94583.1 - 0.062 14.0 0.2 0.062 14.0 0.2 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3139) DUF1378 PF07125.11 CDJ94583.1 - 0.12 12.5 1.9 1.4 9.2 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1378) DUF3899 PF13038.6 CDJ94583.1 - 0.58 10.7 0.0 0.58 10.7 0.0 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF3899) DUF373 PF04123.13 CDJ94583.1 - 0.73 9.2 14.3 1 8.8 14.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF1461 PF07314.11 CDJ94583.1 - 1 9.2 18.1 2.8 7.8 10.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1461) DUF973 PF06157.11 CDJ94583.1 - 2.2 7.2 27.6 0.15 11.1 19.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF973) DUF4834 PF16118.5 CDJ94583.1 - 2.3 9.2 0.0 2.3 9.2 0.0 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4834) Guanylate_cyc PF00211.20 CDJ94585.1 - 2.9e-47 160.7 0.0 5.9e-47 159.7 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOB PF07700.15 CDJ94585.1 - 1.3e-24 87.1 0.0 2.3e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Haem-NO-binding HNOBA PF07701.14 CDJ94585.1 - 1.5e-12 47.5 0.3 1.5e-12 47.5 0.3 2.1 2 0 0 2 2 2 1 Heme NO binding associated SH3_1 PF00018.28 CDJ94586.1 - 2.3e-44 148.8 0.2 1.1e-10 40.9 0.0 4.3 4 0 0 4 4 4 4 SH3 domain SH3_9 PF14604.6 CDJ94586.1 - 1.7e-36 123.8 0.7 2.5e-09 36.8 0.0 4.2 4 0 0 4 4 4 4 Variant SH3 domain SH3_2 PF07653.17 CDJ94586.1 - 1.3e-24 85.7 0.0 6.2e-06 25.8 0.0 4.3 4 0 0 4 4 4 4 Variant SH3 domain DUF5348 PF17295.2 CDJ94586.1 - 0.047 13.6 0.0 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5348) DUF3083 PF11281.8 CDJ94586.1 - 0.15 11.4 0.1 0.22 10.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3083) NTP_transf_2 PF01909.23 CDJ94587.1 - 5.2e-07 29.9 0.0 1.8e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 CDJ94587.1 - 0.0005 20.1 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase RRM_1 PF00076.22 CDJ94587.1 - 0.01 15.7 0.7 0.037 13.9 0.1 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA_NucTransf2 PF09249.11 CDJ94587.1 - 0.096 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain zf-met PF12874.7 CDJ94589.1 - 0.024 15.0 0.2 0.024 15.0 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CDJ94589.1 - 0.056 13.9 13.2 1 10.0 0.5 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ94589.1 - 0.12 13.3 13.5 5.7 8.1 0.5 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CDJ94589.1 - 0.27 11.6 6.7 3.5 8.0 0.3 2.9 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) AAA_11 PF13086.6 CDJ94589.1 - 2.2 8.0 7.6 3.2 7.5 7.6 1.2 1 0 0 1 1 1 0 AAA domain Reprolysin PF01421.19 CDJ94590.1 - 1.7e-24 86.9 0.1 1.7e-24 86.9 0.1 1.8 2 0 0 2 2 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.12 CDJ94590.1 - 3.8e-23 82.1 8.3 3.8e-23 82.1 8.3 4.3 3 2 1 4 4 2 1 ADAM cysteine-rich Disintegrin PF00200.23 CDJ94590.1 - 1.9e-17 63.8 27.9 1.9e-17 63.8 27.9 4.3 4 1 0 4 4 3 1 Disintegrin Reprolysin_5 PF13688.6 CDJ94590.1 - 2.9e-10 40.6 2.9 2.9e-10 40.6 2.9 2.0 2 0 0 2 2 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CDJ94590.1 - 1.1e-07 32.4 0.6 2.3e-07 31.4 0.6 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CDJ94590.1 - 1.2e-07 31.6 0.9 2.1e-07 30.8 0.4 1.5 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 CDJ94590.1 - 3.9e-07 30.2 0.9 7.6e-07 29.2 0.9 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 CDJ94590.1 - 0.052 12.5 0.2 0.1 11.5 0.2 1.4 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.24 CDJ94590.1 - 0.22 11.4 0.1 0.36 10.6 0.1 1.2 1 0 0 1 1 1 0 Matrixin DUF3810 PF12725.7 CDJ94590.1 - 0.3 10.4 1.0 1.3 8.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Zincin_1 PF06262.11 CDJ94590.1 - 0.31 11.2 0.5 0.64 10.2 0.5 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase SMC_N PF02463.19 CDJ94591.1 - 6.1e-30 104.3 0.1 7.9e-30 103.9 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CDJ94591.1 - 8.7e-05 22.5 0.1 0.00011 22.2 0.1 1.4 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 CDJ94591.1 - 0.0013 19.3 0.0 0.0025 18.3 0.0 1.6 1 1 0 1 1 1 1 ABC transporter VPS38 PF17649.1 CDJ94591.1 - 0.0065 15.4 0.3 0.01 14.8 0.3 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting 38 DUF3866 PF12982.7 CDJ94591.1 - 0.032 13.3 0.1 0.39 9.8 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3866) ACOX PF01756.19 CDJ94592.1 - 6.6e-53 178.9 2.4 7.1e-53 178.8 1.5 1.5 2 0 0 2 2 2 1 Acyl-CoA oxidase PIG-L PF02585.17 CDJ94592.1 - 0.07 13.8 0.4 0.18 12.4 0.4 2.0 1 1 0 1 1 1 0 GlcNAc-PI de-N-acetylase Acyl-CoA_dh_1 PF00441.24 CDJ94592.1 - 0.11 12.7 5.6 0.057 13.6 0.8 2.3 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain ACOX PF01756.19 CDJ94593.1 - 3.4e-56 189.7 2.1 5.7e-56 188.9 2.1 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase PIG-L PF02585.17 CDJ94593.1 - 0.009 16.6 0.4 0.02 15.5 0.4 1.9 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase Acyl-CoA_dh_1 PF00441.24 CDJ94593.1 - 0.029 14.6 2.1 0.046 13.9 0.1 2.1 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Sec5 PF15469.6 CDJ94594.1 - 5.1e-41 140.6 5.7 1.2e-40 139.3 5.7 1.7 1 0 0 1 1 1 1 Exocyst complex component Sec5 Tmemb_170 PF10190.9 CDJ94594.1 - 1.2e-19 70.6 7.8 1.2e-19 70.6 7.8 2.1 2 0 0 2 2 2 1 Putative transmembrane protein 170 Metallophos PF00149.28 CDJ94594.1 - 2.2e-11 44.7 0.3 4.5e-11 43.6 0.3 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TIG PF01833.24 CDJ94594.1 - 1.7e-08 34.4 0.0 4.4e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 IPT/TIG domain Metallophos_2 PF12850.7 CDJ94594.1 - 1.8e-06 28.2 0.2 5e-06 26.8 0.2 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain LSM14 PF12701.7 CDJ94595.1 - 0.00044 20.3 0.1 0.0013 18.8 0.1 1.8 1 1 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 CDJ94595.1 - 0.048 14.6 0.3 0.048 14.6 0.3 2.7 2 1 0 2 2 2 0 FDF domain SNRNP27 PF08648.12 CDJ94596.1 - 1.8e-27 95.2 0.8 3.4e-27 94.3 0.8 1.5 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Presenilin PF01080.17 CDJ94596.1 - 1.9 7.2 5.1 2.1 7.0 5.1 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 CDJ94596.1 - 3.7 6.2 10.9 4.2 6.0 10.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cu2_monoox_C PF03712.15 CDJ94597.1 - 3.9e-29 101.2 0.0 9.3e-29 100.0 0.0 1.6 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain NHL PF01436.21 CDJ94597.1 - 2.8e-21 74.4 0.6 3.8e-06 26.7 0.0 4.6 4 0 0 4 4 4 4 NHL repeat Cu2_monooxygen PF01082.20 CDJ94597.1 - 6.4e-18 65.3 0.0 2.5e-17 63.3 0.0 1.9 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Lactonase PF10282.9 CDJ94597.1 - 0.025 13.8 0.0 0.71 9.1 0.0 2.2 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller AAA_29 PF13555.6 CDJ94597.1 - 0.048 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain BRK PF07533.16 CDJ94599.1 - 5.4e-24 83.5 0.2 1.3e-12 47.1 0.1 2.4 2 0 0 2 2 2 2 BRK domain SLIDE PF09111.10 CDJ94599.1 - 0.00078 19.5 0.1 1.3 9.0 0.0 2.8 3 0 0 3 3 3 2 SLIDE IncF PF17626.2 CDJ94600.1 - 0.59 10.5 3.4 1.2 9.5 3.0 1.7 1 1 0 1 1 1 0 Inclusion membrane protein F Ctr PF04145.15 CDJ94603.1 - 1.1e-28 100.7 5.9 8.1e-25 88.2 0.6 2.6 2 1 1 3 3 3 2 Ctr copper transporter family DUF998 PF06197.13 CDJ94603.1 - 0.0026 17.4 1.4 0.03 13.9 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF998) Metallophos PF00149.28 CDJ94606.1 - 5.1e-10 40.2 0.0 8.4e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Acyltransferase PF01553.21 CDJ94606.1 - 0.014 15.0 0.0 5.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Acyltransferase His_Phos_1 PF00300.22 CDJ94607.1 - 2.9e-21 76.1 0.0 1.3e-19 70.7 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Golgin_A5 PF09787.9 CDJ94608.1 - 0.00064 19.3 16.7 0.00064 19.3 16.7 10.7 3 3 7 11 11 11 3 Golgin subfamily A member 5 DUF4250 PF14056.6 CDJ94608.1 - 9 6.3 8.8 56 3.8 0.2 4.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) HSBP1 PF06825.12 CDJ94608.1 - 9.6 6.1 12.4 0.18 11.7 0.7 4.5 3 1 1 4 4 4 0 Heat shock factor binding protein 1 Lipase_2 PF01674.18 CDJ94609.1 - 7.3e-58 195.7 0.1 3.9e-56 190.0 0.1 2.0 1 1 0 1 1 1 1 Lipase (class 2) Hydrolase_4 PF12146.8 CDJ94609.1 - 2.5e-05 23.7 0.0 4.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 CDJ94609.1 - 0.00071 19.5 0.0 0.00096 19.1 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 CDJ94609.1 - 0.0074 15.8 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 CDJ94609.1 - 0.033 14.8 0.0 0.045 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_2 PF01674.18 CDJ94610.1 - 1.3e-67 227.6 0.0 1.5e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 Lipase (class 2) DUF676 PF05057.14 CDJ94610.1 - 2e-06 27.5 0.0 2.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 CDJ94610.1 - 0.0011 18.9 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 CDJ94610.1 - 0.0018 18.1 0.0 0.0043 16.8 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 CDJ94610.1 - 0.0045 16.3 0.0 0.0079 15.5 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ94610.1 - 0.015 14.9 0.1 0.32 10.6 0.1 2.6 2 1 0 2 2 2 0 alpha/beta hydrolase fold E1_4HB PF16191.5 CDJ94610.1 - 0.024 14.8 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 four-helix bundle LCAT PF02450.15 CDJ94610.1 - 0.043 13.0 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase I-set PF07679.16 CDJ94611.1 - 8.2e-13 48.2 0.0 1.2e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ94611.1 - 9.3e-13 48.6 0.0 1.5e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CDJ94611.1 - 2.9e-09 37.1 0.0 4.5e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CDJ94611.1 - 1e-08 35.2 0.0 2.2e-08 34.2 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 CDJ94611.1 - 0.00049 20.2 0.0 0.0064 16.7 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDJ94611.1 - 0.0079 16.2 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 CDJ94611.1 - 0.0087 16.4 0.0 0.013 15.9 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ras PF00071.22 CDJ94612.1 - 1.6e-53 180.7 0.0 1.8e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ94612.1 - 3.7e-19 69.1 0.0 6.5e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ94612.1 - 2.9e-08 33.4 0.0 3.9e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDJ94612.1 - 0.0046 16.5 0.0 0.026 14.1 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PET117 PF15786.5 CDJ94612.1 - 0.026 14.8 0.0 0.041 14.1 0.0 1.3 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial DUF1394 PF07159.12 CDJ94613.1 - 3.4e-100 335.2 0.0 3.9e-100 335.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) DUF647 PF04884.14 CDJ94614.1 - 1.4e-92 309.7 2.2 2.1e-92 309.2 2.2 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Ribosomal_L32e PF01655.18 CDJ94615.1 - 2.7e-46 156.4 0.5 3.4e-46 156.1 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 tRNA-synt_1e PF01406.19 CDJ94615.1 - 0.02 14.3 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain An_peroxidase PF03098.15 CDJ94617.1 - 2.2e-162 541.4 0.0 2.7e-162 541.1 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase ShK PF01549.24 CDJ94617.1 - 3.8e-14 52.9 28.2 3.5e-08 33.8 4.9 3.3 3 0 0 3 3 3 2 ShK domain-like GAGE PF05831.11 CDJ94617.1 - 1.8 9.2 11.1 3.2 8.4 10.5 1.7 1 1 0 1 1 1 0 GAGE protein CDC45 PF02724.14 CDJ94617.1 - 4.4 5.5 5.5 6.2 5.0 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein COMPASS-Shg1 PF05205.12 CDJ94618.1 - 1.3e-07 32.3 1.2 1.9e-07 31.7 1.2 1.3 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 DUF1816 PF08846.10 CDJ94618.1 - 0.1 12.6 0.0 5.8 7.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1816) COMPASS-Shg1 PF05205.12 CDJ94619.1 - 1.3e-07 32.3 1.2 1.9e-07 31.7 1.2 1.3 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 DUF1816 PF08846.10 CDJ94619.1 - 0.1 12.6 0.0 5.8 7.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1816) DUF229 PF02995.17 CDJ94620.1 - 1.7e-92 310.6 0.3 2.1e-92 310.3 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 CDJ94620.1 - 0.0021 17.5 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Thioredoxin_6 PF13848.6 CDJ94620.1 - 0.022 14.7 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like domain 7TM_GPCR_Srx PF10328.9 CDJ94622.1 - 2.7e-43 148.5 23.9 3.3e-43 148.2 23.9 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 CDJ94622.1 - 1.7e-06 27.6 12.8 2e-06 27.4 12.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srt PF10321.9 CDJ94622.1 - 3.7e-06 26.2 15.1 4.7e-06 25.8 15.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt 7TM_GPCR_Srbc PF10316.9 CDJ94622.1 - 4.2e-05 23.2 3.9 4.2e-05 23.2 3.9 2.4 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7tm_1 PF00001.21 CDJ94622.1 - 0.0035 16.7 13.7 0.005 16.2 13.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ94622.1 - 0.6 9.4 19.2 0.042 13.2 10.6 2.1 1 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 CDJ94623.1 - 4.1e-59 200.3 30.2 5.2e-59 200.0 30.2 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srt PF10321.9 CDJ94623.1 - 2.7e-05 23.3 22.8 4.9e-05 22.5 22.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt 7TM_GPCR_Srsx PF10320.9 CDJ94623.1 - 0.00034 20.1 12.4 0.00034 20.1 12.4 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srbc PF10316.9 CDJ94623.1 - 0.00051 19.6 10.2 0.00051 19.6 10.2 2.5 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7tm_1 PF00001.21 CDJ94623.1 - 0.016 14.6 17.6 0.022 14.1 17.6 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) TssO PF17561.2 CDJ94623.1 - 6.5 6.8 6.1 9.2 6.4 0.9 2.5 2 0 0 2 2 2 0 Type VI secretion system, TssO Y_phosphatase PF00102.27 CDJ94624.1 - 4.7e-66 222.7 0.0 7e-66 222.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ94624.1 - 0.00021 21.1 0.2 0.0011 18.8 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDJ94624.1 - 0.0048 16.9 0.0 0.0097 15.9 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CDJ94625.1 - 2.2e-66 223.8 0.0 7e-40 137.1 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ94625.1 - 0.00051 19.9 0.1 0.0032 17.3 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDJ94625.1 - 0.0074 16.3 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CDJ94626.1 - 1.1e-62 211.6 0.0 1.5e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ94626.1 - 0.002 18.0 0.0 0.0047 16.8 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDJ94626.1 - 0.0082 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Forkhead PF00250.18 CDJ94627.1 - 1.1e-30 105.7 0.7 2e-30 104.9 0.3 1.6 2 0 0 2 2 2 1 Forkhead domain Linker_histone PF00538.19 CDJ94627.1 - 0.073 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 linker histone H1 and H5 family CRAL_TRIO PF00650.20 CDJ94628.1 - 4.3e-23 81.8 0.0 6.7e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CDJ94628.1 - 0.08 13.1 0.0 0.18 11.9 0.0 1.6 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain DUF4512 PF14975.6 CDJ94629.1 - 2.4e-05 25.0 12.6 0.00021 22.0 12.6 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4512) GNAT_acetyltr_2 PF13718.6 CDJ94631.1 - 6.5e-75 251.4 1.9 4.9e-58 196.2 0.0 3.0 2 1 1 3 3 3 2 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 CDJ94631.1 - 3.7e-64 216.7 8.8 5.3e-64 216.1 8.8 1.2 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 CDJ94631.1 - 5.6e-64 215.2 0.0 2.5e-63 213.1 0.0 2.2 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 CDJ94631.1 - 9.5e-33 112.0 0.1 3.7e-32 110.1 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) Acetyltransf_7 PF13508.7 CDJ94631.1 - 2.5e-05 24.6 0.0 7.3e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_30 PF13604.6 CDJ94631.1 - 0.00074 19.3 0.0 2.3 7.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain Acetyltransf_1 PF00583.25 CDJ94631.1 - 0.0021 18.3 0.0 0.0047 17.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family AAA_22 PF13401.6 CDJ94631.1 - 0.0092 16.3 0.0 1.6 9.0 0.0 3.1 2 0 0 2 2 2 1 AAA domain Acetyltransf_10 PF13673.7 CDJ94631.1 - 0.031 14.2 0.0 0.093 12.7 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GvpL_GvpF PF06386.11 CDJ94631.1 - 0.21 11.5 1.3 18 5.2 0.5 2.6 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF zf-C3Hc3H PF13891.6 CDJ94632.1 - 8.4e-13 48.5 2.5 1.7e-12 47.5 2.5 1.5 1 0 0 1 1 1 1 Potential DNA-binding domain zf-primase PF09329.11 CDJ94632.1 - 0.74 9.7 4.1 0.34 10.7 0.6 2.2 1 1 1 2 2 2 0 Primase zinc finger WRC PF08879.10 CDJ94632.1 - 4 7.2 7.3 4.2 7.2 0.0 3.2 2 1 1 3 3 3 0 WRC ATP_bind_1 PF03029.17 CDJ94633.1 - 4.2e-86 288.7 0.2 4.7e-86 288.5 0.2 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 CDJ94633.1 - 1.4e-06 28.2 0.0 1.7e-05 24.7 0.0 2.5 1 1 2 3 3 3 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_17 PF13207.6 CDJ94633.1 - 0.00014 22.2 1.1 1.2 9.6 0.1 3.1 2 1 1 3 3 3 2 AAA domain AAA_18 PF13238.6 CDJ94633.1 - 0.00055 20.5 0.5 0.069 13.7 0.0 2.8 1 1 1 2 2 2 1 AAA domain GTP_EFTU PF00009.27 CDJ94633.1 - 0.095 12.2 0.2 0.25 10.9 0.2 1.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain CbiA PF01656.23 CDJ94633.1 - 0.13 12.3 0.0 0.17 11.9 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CDJ94633.1 - 0.15 12.0 0.1 11 5.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 CDJ94633.1 - 0.18 12.0 0.0 0.77 9.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain IML1 PF12257.8 CDJ94634.1 - 2.4e-93 312.4 0.3 3.6e-93 311.8 0.3 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 SF3b1 PF08920.10 CDJ94635.1 - 8e-45 152.2 20.7 3.1e-41 140.6 1.1 4.7 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 CDJ94635.1 - 8.2e-10 38.9 4.8 0.94 9.9 0.0 7.3 4 2 4 8 8 8 2 HEAT repeats HEAT PF02985.22 CDJ94635.1 - 6.5e-09 35.3 11.0 0.12 12.7 0.0 8.7 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.6 CDJ94635.1 - 8.5e-08 32.5 10.0 0.97 10.0 0.0 8.0 9 1 1 10 10 9 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CDJ94635.1 - 1.4e-05 25.6 2.0 2.5 8.7 0.0 5.6 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CDJ94635.1 - 0.00021 21.4 5.8 0.84 9.7 0.0 5.5 5 1 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 CDJ94635.1 - 0.001 18.3 0.0 11 5.0 0.0 4.2 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 CDJ94635.1 - 0.0034 17.0 0.8 3.7 7.0 0.1 3.4 4 0 0 4 4 4 2 CLASP N terminal Adaptin_N PF01602.20 CDJ94635.1 - 0.0043 15.7 0.2 0.14 10.6 0.1 2.9 1 1 0 1 1 1 1 Adaptin N terminal region Dopey_N PF04118.14 CDJ94635.1 - 0.005 16.0 0.8 0.27 10.3 0.1 3.6 2 1 2 4 4 4 1 Dopey, N-terminal UNC45-central PF11701.8 CDJ94635.1 - 0.014 15.4 0.0 0.049 13.6 0.0 1.9 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central NUC173 PF08161.12 CDJ94635.1 - 0.014 15.1 0.2 1.1 8.9 0.0 3.8 5 0 0 5 5 5 0 NUC173 domain CDH PF02611.15 CDJ94635.1 - 0.16 11.5 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase DNA_pol_phi PF04931.13 CDJ94635.1 - 4.3 5.3 4.3 15 3.5 0.0 2.5 3 0 0 3 3 3 0 DNA polymerase phi UPF0542 PF15086.6 CDJ94636.1 - 0.18 11.7 1.0 7.8 6.5 0.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Vpu PF00558.19 CDJ94636.1 - 2.3 8.1 5.0 23 4.8 5.0 2.3 1 1 0 1 1 1 0 Vpu protein Sugar_tr PF00083.24 CDJ94637.1 - 7e-08 31.8 12.5 2.4e-06 26.7 12.5 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Armet PF10208.9 CDJ94637.1 - 0.0086 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding MFS_1 PF07690.16 CDJ94637.1 - 0.019 13.9 9.2 0.034 13.1 3.3 2.3 1 1 1 2 2 2 0 Major Facilitator Superfamily DUF983 PF06170.12 CDJ94637.1 - 0.024 15.0 0.5 0.024 15.0 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF983) DIT1_PvcA PF05141.12 CDJ94638.1 - 0.012 15.0 0.8 0.013 15.0 0.8 1.0 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein SAM_3 PF18016.1 CDJ94638.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) VitK2_biosynth PF02621.14 CDJ94638.1 - 0.066 12.7 0.4 0.086 12.3 0.4 1.1 1 0 0 1 1 1 0 Menaquinone biosynthesis MFS_1 PF07690.16 CDJ94639.1 - 4.7e-44 150.8 35.4 9.2e-44 149.8 30.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Rubella_Capsid PF05750.11 CDJ94639.1 - 7.8 6.0 9.4 12 5.4 8.7 1.6 1 1 1 2 2 2 0 Rubella capsid protein RVT_1 PF00078.27 CDJ94640.1 - 7.9e-06 25.5 0.0 1.9e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_ligase_A_M PF01068.21 CDJ94641.1 - 3.3e-41 141.2 0.0 7e-41 140.1 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CDJ94641.1 - 1e-16 61.7 0.5 2.9e-16 60.3 0.1 2.0 2 0 0 2 2 2 1 DNA ligase N terminus BRCT_2 PF16589.5 CDJ94641.1 - 2.9e-05 24.4 0.0 0.0002 21.7 0.0 2.4 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain PNKP_ligase PF16542.5 CDJ94641.1 - 3.5e-05 23.5 0.0 0.028 13.9 0.0 2.4 1 1 1 2 2 2 2 PNKP adenylyltransferase domain, ligase domain mRNA_cap_enzyme PF01331.19 CDJ94641.1 - 0.0016 18.3 0.0 0.0065 16.3 0.0 2.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain BRCT PF00533.26 CDJ94641.1 - 0.0032 17.8 0.0 0.015 15.7 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain tRNA_m1G_MT PF01746.21 CDJ94641.1 - 0.011 15.5 0.0 0.084 12.6 0.0 2.2 1 1 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase DNA_ligase_A_C PF04679.15 CDJ94641.1 - 0.082 13.5 0.0 0.48 11.1 0.0 2.4 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region DENN PF02141.21 CDJ94642.1 - 6.1e-41 140.4 0.3 1.4e-40 139.3 0.3 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 CDJ94642.1 - 6.6e-10 38.8 5.1 1.8e-09 37.4 5.1 1.8 1 0 0 1 1 1 1 dDENN domain PPR_2 PF13041.6 CDJ94642.1 - 2.4e-05 24.5 0.0 0.00017 21.7 0.0 2.2 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.20 CDJ94642.1 - 0.025 14.8 0.0 0.065 13.5 0.0 1.8 1 0 0 1 1 1 0 PPR repeat PPR_3 PF13812.6 CDJ94642.1 - 0.082 13.0 0.0 0.24 11.5 0.0 1.8 1 1 1 2 2 2 0 Pentatricopeptide repeat domain Ly-6_related PF06579.12 CDJ94643.1 - 1.1e-38 132.2 3.5 1.5e-38 131.8 3.5 1.2 1 0 0 1 1 1 1 Caenorhabditis elegans ly-6-related protein DCX PF03607.17 CDJ94644.1 - 3.5e-14 52.7 0.1 8.5e-14 51.4 0.0 1.7 2 0 0 2 2 2 1 Doublecortin Med26 PF08711.11 CDJ94646.1 - 1.3e-05 25.1 0.2 4.6e-05 23.4 0.2 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF3300 PF11737.8 CDJ94646.1 - 0.11 12.0 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) CBS PF00571.28 CDJ94647.1 - 1.6e-15 57.3 4.3 8.3e-06 26.2 0.1 4.5 4 0 0 4 4 4 3 CBS domain Ldt_C PF17969.1 CDJ94647.1 - 0.092 13.5 0.2 0.54 11.0 0.1 2.2 2 0 0 2 2 2 0 L,D-transpeptidase C-terminal domain TMEM154 PF15102.6 CDJ94647.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Tlr3_TMD PF17968.1 CDJ94647.1 - 0.59 10.4 2.7 1.5 9.1 2.7 1.6 1 0 0 1 1 1 0 Toll-like receptor 3 trans-membrane domain RVT_1 PF00078.27 CDJ94648.1 - 6.5e-13 48.7 1.1 2.7e-12 46.7 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF272 PF03312.15 CDJ94649.1 - 4.5e-12 46.3 0.0 2.2e-11 44.1 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF272) Mac-1 PF09028.10 CDJ94649.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Mac 1 Serpin PF00079.20 CDJ94651.1 - 3e-08 33.4 0.0 9.2e-08 31.8 0.0 1.8 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) Proteasome PF00227.26 CDJ94651.1 - 0.21 11.0 0.1 1.4 8.4 0.0 2.2 3 0 0 3 3 3 0 Proteasome subunit PhoLip_ATPase_C PF16212.5 CDJ94652.1 - 9.1e-79 264.7 32.0 9.1e-79 264.7 32.0 2.8 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CDJ94652.1 - 1.7e-27 94.9 7.2 1.7e-27 94.9 7.2 2.3 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CDJ94652.1 - 7.6e-13 48.4 0.3 6.4e-11 42.2 0.0 2.7 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CDJ94652.1 - 2.5e-09 37.7 0.3 0.00018 21.8 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CDJ94652.1 - 1e-05 25.1 1.1 0.00011 21.8 0.0 2.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CDJ94652.1 - 0.0011 18.8 0.3 0.018 14.8 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Prominin PF05478.11 CDJ94652.1 - 2.8 5.8 5.8 0.43 8.5 0.5 2.0 2 0 0 2 2 2 0 Prominin PBP PF01161.20 CDJ94653.1 - 1.3e-18 67.6 0.0 1.6e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Fic PF02661.18 CDJ94654.1 - 1.5e-24 86.7 0.0 3.6e-24 85.5 0.0 1.7 1 0 0 1 1 1 1 Fic/DOC family TPR_14 PF13428.6 CDJ94655.1 - 0.071 14.0 0.1 0.15 13.0 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Antimicrobial_2 PF08023.12 CDJ94656.1 - 0.012 16.1 4.6 0.59 10.7 0.1 2.9 3 0 0 3 3 3 0 Frog antimicrobial peptide Folliculin PF11704.8 CDJ94656.1 - 0.16 11.9 0.9 0.4 10.6 0.6 1.8 1 1 1 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Ku_C PF03730.14 CDJ94656.1 - 0.25 12.1 3.6 0.57 10.9 0.7 2.6 2 1 1 3 3 3 0 Ku70/Ku80 C-terminal arm YlbD_coat PF14071.6 CDJ94657.1 - 0.025 14.8 0.7 0.065 13.5 0.0 1.9 2 0 0 2 2 2 0 Putative coat protein YlbD_coat PF14071.6 CDJ94658.1 - 0.025 14.8 0.7 0.065 13.5 0.0 1.9 2 0 0 2 2 2 0 Putative coat protein Peptidase_A17 PF05380.13 CDJ94659.1 - 1.4e-44 151.9 0.0 6e-44 149.9 0.0 2.0 2 0 0 2 2 2 1 Pao retrotransposon peptidase DUF5641 PF18701.1 CDJ94659.1 - 2.8e-18 65.9 0.1 6.9e-18 64.6 0.1 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5641) rve PF00665.26 CDJ94659.1 - 3e-10 40.3 0.0 7.5e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ94659.1 - 1e-07 31.9 1.2 3.7e-07 30.1 1.2 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 CDJ94659.1 - 2.1e-05 24.1 0.0 4.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 CDJ94659.1 - 0.018 14.8 0.0 0.063 13.1 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain Myosin-VI_CBD PF16521.5 CDJ94660.1 - 8.6e-39 131.4 1.3 2.4e-38 130.0 0.0 2.3 2 0 0 2 2 2 1 Myosin VI cargo binding domain IQ PF00612.27 CDJ94660.1 - 9.6e-05 21.9 1.4 9.6e-05 21.9 1.4 2.4 2 0 0 2 2 2 1 IQ calmodulin-binding motif XRN_M PF17846.1 CDJ94660.1 - 0.063 12.2 5.1 0.089 11.7 5.1 1.3 1 0 0 1 1 1 0 Xrn1 helical domain Asp-B-Hydro_N PF05279.11 CDJ94660.1 - 3.4 7.7 13.7 5.6 7.0 13.7 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region V_ATPase_I PF01496.19 CDJ94660.1 - 4.4 5.1 9.0 5.2 4.9 9.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mucin PF01456.17 CDJ94661.1 - 0.00049 20.1 20.9 0.34 10.9 2.4 3.2 3 0 0 3 3 3 3 Mucin-like glycoprotein DUF3523 PF12037.8 CDJ94661.1 - 1.2 8.4 15.0 2.1 7.6 15.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) BAF250_C PF12031.8 CDJ94664.1 - 2.2e-71 240.1 0.7 3.3e-71 239.6 0.7 1.3 1 0 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa Med25 PF11232.8 CDJ94664.1 - 0.1 12.6 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Mediator complex subunit 25 PTOV activation and synapsin 2 RabGAP-TBC PF00566.18 CDJ94665.1 - 4.7e-09 36.2 1.3 7.3e-09 35.6 1.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Sec61_beta PF03911.16 CDJ94666.1 - 6.1e-20 71.0 0.0 7.2e-20 70.7 0.0 1.1 1 0 0 1 1 1 1 Sec61beta family PEHE PF15275.6 CDJ94668.1 - 0.0004 21.0 2.4 0.0004 21.0 2.4 1.9 2 0 0 2 2 2 1 PEHE domain Herpes_LMP1 PF05297.11 CDJ94669.1 - 0.0055 16.0 7.3 0.0068 15.6 7.3 1.2 1 0 0 1 1 1 1 Herpesvirus latent membrane protein 1 (LMP1) DUF4173 PF13777.6 CDJ94669.1 - 0.0073 15.7 4.3 0.0073 15.7 4.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4173) CPP1-like PF11833.8 CDJ94669.1 - 0.013 15.2 5.7 0.02 14.6 5.3 1.6 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF3792 PF12670.7 CDJ94669.1 - 0.039 14.1 21.6 0.054 13.7 21.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) Orf78 PF06024.12 CDJ94669.1 - 1.1 9.6 0.0 1.1 9.6 0.0 3.2 2 1 1 3 3 3 0 Orf78 (ac78) DUF1129 PF06570.11 CDJ94669.1 - 4.1 6.8 10.7 7.7 6.0 10.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2157 PF09925.9 CDJ94669.1 - 4.6 7.0 14.4 8.9 6.1 14.4 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) AGTRAP PF06396.11 CDJ94669.1 - 5 6.9 11.7 7.8 6.3 11.6 1.4 1 1 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) 7tm_7 PF08395.12 CDJ94669.1 - 5.2 6.2 11.4 0.47 9.6 2.5 2.0 1 1 1 2 2 2 0 7tm Chemosensory receptor DUF2070 PF09843.9 CDJ94669.1 - 7.9 4.6 17.7 9.9 4.3 17.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4231 PF14015.6 CDJ94669.1 - 8.3 6.9 14.3 1.2 9.6 2.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) FOXP-CC PF16159.5 CDJ94670.1 - 0.055 14.1 0.1 0.088 13.5 0.1 1.3 1 0 0 1 1 1 0 FOXP coiled-coil domain ThiF PF00899.21 CDJ94671.1 - 1.2e-68 231.1 0.0 1.5e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 CDJ94671.1 - 0.015 15.4 0.1 0.033 14.3 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase UBA_e1_thiolCys PF10585.9 CDJ94671.1 - 0.16 11.9 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-activating enzyme active site DUF35_N PF12172.8 CDJ94671.1 - 0.38 10.7 2.5 5.3 7.0 0.9 2.5 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Rep_fac-A_C PF08646.10 CDJ94672.1 - 1e-44 151.8 2.5 2.8e-44 150.4 1.2 2.1 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 CDJ94672.1 - 7.4e-24 83.5 0.2 2e-20 72.5 0.0 2.7 3 0 0 3 3 3 2 Replication protein A OB domain tRNA_anti-codon PF01336.25 CDJ94672.1 - 2.9e-11 43.2 0.0 3.2e-05 23.8 0.0 3.4 3 0 0 3 3 3 3 OB-fold nucleic acid binding domain DUF1840 PF08895.11 CDJ94673.1 - 4.6 7.6 6.7 10 6.5 0.0 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1840) Pkinase PF00069.25 CDJ94675.1 - 2.5e-22 79.5 0.1 3e-22 79.2 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ94675.1 - 9.4e-14 51.3 0.0 1.1e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ94675.1 - 1.5e-05 24.0 0.0 2.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDJ94675.1 - 0.00045 20.2 0.0 0.017 15.0 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Glyco_transf_29 PF00777.18 CDJ94675.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 29 (sialyltransferase) Dicer_dimer PF03368.14 CDJ94675.1 - 0.14 12.4 0.2 1.7 8.8 0.0 2.6 2 1 1 3 3 3 0 Dicer dimerisation domain WW PF00397.26 CDJ94676.1 - 4.2e-10 39.5 6.2 5.9e-08 32.7 0.3 2.5 2 0 0 2 2 2 2 WW domain Glyco_tran_10_N PF17039.5 CDJ94677.1 - 2.1e-13 50.7 0.0 3.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Sprouty PF05210.13 CDJ94677.1 - 1.2 9.5 3.0 0.55 10.6 0.7 1.5 2 0 0 2 2 2 0 Sprouty protein (Spry) Y_phosphatase PF00102.27 CDJ94678.1 - 4.5e-126 419.2 0.0 9.1e-71 238.1 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CDJ94678.1 - 1.6e-06 28.3 0.0 0.0047 16.9 0.0 2.6 2 0 0 2 2 2 2 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CDJ94678.1 - 0.00019 21.6 0.0 0.0085 16.2 0.0 2.5 2 0 0 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.20 CDJ94678.1 - 0.00033 20.5 0.0 0.012 15.4 0.0 2.4 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 CDJ94678.1 - 0.0093 15.6 0.0 0.35 10.4 0.0 2.7 2 0 0 2 2 2 1 Tyrosine phosphatase family BrkDBD PF09607.10 CDJ94678.1 - 0.13 12.1 0.1 0.3 10.9 0.1 1.6 1 0 0 1 1 1 0 Brinker DNA-binding domain EGF_2 PF07974.13 CDJ94681.1 - 0.021 15.2 2.1 0.047 14.1 2.1 1.6 1 0 0 1 1 1 0 EGF-like domain DUF4750 PF15938.5 CDJ94681.1 - 0.084 12.5 0.6 0.15 11.7 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4750) Moulting_cycle PF04870.16 CDJ94682.1 - 6e-100 334.9 11.4 1.1e-99 334.0 11.4 1.4 1 0 0 1 1 1 1 Moulting cycle Sec1 PF00995.23 CDJ94682.1 - 0.026 13.8 3.7 0.035 13.3 3.7 1.3 1 0 0 1 1 1 0 Sec1 family GP3_package PF16677.5 CDJ94682.1 - 0.034 14.3 0.1 0.096 12.8 0.1 1.7 1 0 0 1 1 1 0 DNA-packaging protein gp3 REV1_C PF16727.5 CDJ94682.1 - 0.42 11.0 3.0 3.5 8.1 0.2 3.0 3 0 0 3 3 3 0 DNA repair protein REV1 C-terminal domain Myb_DNA-bind_3 PF12776.7 CDJ94682.1 - 4.8 8.2 7.3 2.9 8.9 3.1 2.7 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain TMPIT PF07851.13 CDJ94682.1 - 6.9 5.8 7.7 13 4.9 7.7 1.4 1 0 0 1 1 1 0 TMPIT-like protein RVT_1 PF00078.27 CDJ94683.1 - 6.1e-36 124.0 0.0 1.1e-35 123.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDJ94683.1 - 8.2e-08 32.1 0.0 2.6e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Collagen PF01391.18 CDJ94684.1 - 4.9e-25 87.1 93.6 3.5e-10 39.5 29.8 4.0 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ94684.1 - 7.4e-20 70.8 1.8 9.4e-20 70.4 1.8 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Y_phosphatase PF00102.27 CDJ94685.1 - 6.4e-27 94.6 0.1 8.7e-27 94.2 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase ECH_1 PF00378.20 CDJ94686.1 - 5.6e-44 150.3 0.1 1.3e-43 149.1 0.1 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CDJ94686.1 - 8.7e-29 101.1 0.0 2e-28 99.9 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ICEA PF05315.11 CDJ94686.1 - 0.028 13.9 0.1 0.041 13.3 0.1 1.3 1 0 0 1 1 1 0 ICEA Protein BCDHK_Adom3 PF10436.9 CDJ94686.1 - 0.03 14.2 0.0 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Ribosomal_L14 PF00238.19 CDJ94688.1 - 4.2e-22 78.5 0.1 8e-22 77.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e NDUF_B5 PF09781.9 CDJ94689.1 - 2.9e-16 59.6 1.6 3.7e-16 59.3 1.6 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit AalphaY_MDB PF04611.12 CDJ94689.1 - 0.18 11.8 0.5 0.28 11.2 0.5 1.3 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region VPS13 PF16908.5 CDJ94690.1 - 7.8e-51 173.1 0.0 1.3e-50 172.4 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 CDJ94690.1 - 1.4e-34 118.7 0.2 3e-34 117.6 0.2 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 Integrin_b_cyt PF08725.11 CDJ94690.1 - 0.043 13.5 0.8 0.11 12.2 0.8 1.7 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain Collagen PF01391.18 CDJ94692.1 - 2.2e-27 94.6 95.2 1.3e-10 40.8 31.9 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ94692.1 - 0.007 16.4 0.2 0.012 15.7 0.2 1.4 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain VPS13_C PF16909.5 CDJ94693.1 - 6.7e-18 65.1 9.0 3.9e-13 49.6 0.5 3.6 2 2 2 4 4 4 3 Vacuolar-sorting-associated 13 protein C-terminal CitX PF03802.14 CDJ94693.1 - 0.057 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase Aph-1 PF06105.12 CDJ94693.1 - 0.27 10.6 1.3 6.1 6.2 0.2 2.1 1 1 1 2 2 2 0 Aph-1 protein PET117 PF15786.5 CDJ94694.1 - 7e-07 29.4 6.0 1.4e-06 28.5 6.0 1.5 1 1 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial GST_N_4 PF17172.4 CDJ94695.1 - 3.1e-20 72.8 0.0 7.3e-20 71.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 CDJ94695.1 - 3.1e-14 52.5 0.0 6.5e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDJ94695.1 - 5.8e-10 39.1 0.0 1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDJ94695.1 - 6.1e-07 29.6 0.0 1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDJ94695.1 - 4.7e-06 26.7 0.0 8e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDJ94695.1 - 0.00011 22.5 0.0 0.00065 20.1 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain S_100 PF01023.19 CDJ94695.1 - 0.042 13.5 0.0 0.6 9.8 0.0 2.6 3 0 0 3 3 3 0 S-100/ICaBP type calcium binding domain RVT_1 PF00078.27 CDJ94696.1 - 8.9e-12 45.0 0.0 1.5e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CDJ94696.1 - 4.6e-08 33.5 0.0 1.7e-07 31.7 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ94696.1 - 8.3e-07 29.6 0.0 1.9e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ94696.1 - 5e-06 26.7 0.0 1.2e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC_3 PF13917.6 CDJ94696.1 - 0.042 13.8 8.8 0.44 10.5 3.3 2.8 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 CDJ94696.1 - 0.27 11.4 10.3 3.6 7.8 1.8 2.6 2 0 0 2 2 2 0 Zinc knuckle YppG PF14179.6 CDJ94697.1 - 0.15 12.7 1.4 0.72 10.6 0.0 2.3 2 0 0 2 2 2 0 YppG-like protein 7tm_1 PF00001.21 CDJ94698.1 - 3.2e-06 26.7 12.9 4.1e-06 26.3 12.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Tegument_dsDNA PF12818.7 CDJ94698.1 - 0.028 13.6 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 dsDNA viral tegument protein Vps55 PF04133.14 CDJ94698.1 - 0.52 10.3 8.1 0.26 11.3 3.0 2.6 2 1 0 2 2 2 0 Vacuolar protein sorting 55 NADHdh_A3 PF14987.6 CDJ94699.1 - 0.063 13.6 0.0 0.085 13.2 0.0 1.3 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 DUF4964 PF16334.5 CDJ94699.1 - 0.17 11.5 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) Exo_endo_phos PF03372.23 CDJ94700.1 - 0.0006 19.4 0.0 0.0018 17.9 0.0 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CDJ94700.1 - 0.014 15.2 0.0 0.058 13.2 0.0 2.0 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase wnt PF00110.19 CDJ94702.1 - 1.3e-112 376.4 21.4 1.4e-112 376.2 21.4 1.0 1 0 0 1 1 1 1 wnt family MFP2b PF12150.8 CDJ94704.1 - 8.8e-154 511.9 0.6 3.1e-80 270.1 0.1 2.0 2 0 0 2 2 2 2 Cytosolic motility protein DUF3421 PF11901.8 CDJ94704.1 - 0.00015 21.7 0.9 0.0014 18.6 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3421) CH PF00307.31 CDJ94705.1 - 5.1e-28 97.4 0.9 9.7e-16 57.9 0.1 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CH_2 PF06294.11 CDJ94705.1 - 0.00015 21.9 0.0 0.11 12.6 0.0 2.8 3 0 0 3 3 3 2 CH-like domain in sperm protein CAMSAP_CH PF11971.8 CDJ94705.1 - 0.00019 21.2 0.0 0.085 12.7 0.0 2.8 2 1 1 3 3 3 2 CAMSAP CH domain DEAD PF00270.29 CDJ94706.1 - 2.7e-51 173.8 0.0 6.9e-51 172.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ94706.1 - 2.8e-29 101.7 0.1 2.8e-28 98.5 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CdAMP_rec PF06153.11 CDJ94706.1 - 0.13 12.5 0.1 0.38 11.0 0.1 1.8 1 0 0 1 1 1 0 Cyclic-di-AMP receptor Bac_luciferase PF00296.20 CDJ94706.1 - 1.9 7.8 6.9 0.15 11.5 1.1 2.0 2 0 0 2 2 2 0 Luciferase-like monooxygenase MFP2b PF12150.8 CDJ94707.1 - 2.2e-150 500.7 0.1 1.6e-79 267.7 0.0 2.0 2 0 0 2 2 2 2 Cytosolic motility protein DUF3421 PF11901.8 CDJ94707.1 - 0.00014 21.9 0.3 0.001 19.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3421) CCSMST1 PF15013.6 CDJ94708.1 - 8.5e-08 32.3 0.0 1.7e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 CCSMST1 family Pyridoxal_deC PF00282.19 CDJ94709.1 - 6.3e-26 91.0 0.0 9.6e-26 90.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CDJ94709.1 - 6.4e-12 45.1 0.0 1.5e-11 43.9 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CDJ94709.1 - 0.011 15.1 0.2 0.021 14.1 0.2 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase WW PF00397.26 CDJ94710.1 - 4.2e-06 26.7 1.6 8.5e-06 25.8 1.6 1.6 1 0 0 1 1 1 1 WW domain Frag1 PF10277.9 CDJ94710.1 - 0.00085 18.9 4.3 0.0011 18.5 4.3 1.2 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family RPN7 PF10602.9 CDJ94711.1 - 2.1e-61 206.7 0.3 3.7e-61 205.8 0.3 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 CDJ94711.1 - 3.5e-16 59.6 0.0 1.1e-15 58.0 0.0 1.9 1 0 0 1 1 1 1 PCI domain HTH_11 PF08279.12 CDJ94711.1 - 0.0058 16.5 0.0 0.016 15.1 0.0 1.8 1 0 0 1 1 1 1 HTH domain DUF1421 PF07223.11 CDJ94711.1 - 0.15 11.9 0.1 0.34 10.8 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain (DUF1421) Methyltransf_11 PF08241.12 CDJ94712.1 - 9.8e-16 58.2 0.1 6.1e-15 55.6 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ94712.1 - 2.9e-12 47.1 0.1 5.3e-10 39.9 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ94712.1 - 1.8e-10 40.8 0.0 5.9e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_8 PF05148.15 CDJ94712.1 - 6e-07 29.5 0.0 7.5e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_23 PF13489.6 CDJ94712.1 - 1.1e-06 28.6 0.0 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ94712.1 - 2e-05 25.2 0.1 0.043 14.6 0.0 2.5 2 1 1 3 3 3 2 Methyltransferase domain MetW PF07021.12 CDJ94712.1 - 3.8e-05 23.4 0.0 7.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 CDJ94712.1 - 0.0062 15.9 0.0 0.0098 15.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 CDJ94712.1 - 0.02 15.9 0.2 0.31 12.1 0.2 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 CDJ94712.1 - 0.089 12.1 0.0 1.7 7.9 0.0 2.1 1 1 0 1 1 1 0 O-methyltransferase domain ATP_synt_H PF05493.13 CDJ94714.1 - 4.5e-24 84.7 4.4 5.6e-24 84.4 4.4 1.1 1 0 0 1 1 1 1 ATP synthase subunit H GON PF08685.11 CDJ94715.1 - 2.7e-70 236.3 0.1 2.7e-70 236.3 0.1 2.3 2 0 0 2 2 1 1 GON domain TSP_1 PF00090.19 CDJ94715.1 - 8.2e-60 198.8 279.1 2.3e-06 27.7 1.7 20.0 20 0 0 20 20 18 17 Thrombospondin type 1 domain ADAM_spacer1 PF05986.14 CDJ94715.1 - 9.5e-30 103.0 0.1 1.6e-29 102.2 0.1 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.19 CDJ94715.1 - 8.4e-25 87.8 0.3 1.7e-24 86.8 0.3 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 CDJ94715.1 - 1.3e-15 58.1 1.1 3.6e-15 56.6 1.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 ADAM_CR_2 PF17771.1 CDJ94715.1 - 6.6e-15 55.4 10.7 6.6e-15 55.4 10.7 11.5 10 5 4 14 14 4 2 ADAM cysteine-rich domain Reprolysin_3 PF13582.6 CDJ94715.1 - 5.9e-12 46.2 0.1 1.1e-11 45.3 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 CDJ94715.1 - 1.5e-06 28.2 0.1 2.9e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 CDJ94715.1 - 3.4e-05 24.1 0.0 9e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_4 PF13583.6 CDJ94715.1 - 0.013 15.2 0.1 0.024 14.3 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DAGK_cat PF00781.24 CDJ94715.1 - 0.15 11.7 0.0 0.4 10.3 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain LSM PF01423.22 CDJ94716.1 - 2.1e-15 56.2 0.4 2.3e-15 56.0 0.4 1.0 1 0 0 1 1 1 1 LSM domain RRM_1 PF00076.22 CDJ94717.1 - 4.2e-35 119.4 2.0 1.2e-16 60.3 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ94717.1 - 6.9e-18 64.6 0.8 5.2e-10 39.3 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CDJ94717.1 - 3.7e-09 36.5 0.2 0.00041 20.3 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.11 CDJ94717.1 - 0.029 14.4 0.1 3.3 7.8 0.0 2.5 1 1 1 2 2 2 0 RNA binding domain Homeodomain PF00046.29 CDJ94718.1 - 3e-22 78.2 9.1 6.8e-22 77.1 8.8 1.7 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CDJ94718.1 - 0.0028 17.5 0.7 0.0054 16.6 0.7 1.5 1 0 0 1 1 1 1 Homeobox KN domain DUF5352 PF17303.2 CDJ94719.1 - 5.2e-55 185.9 0.8 6.2e-55 185.6 0.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5352) ECH_2 PF16113.5 CDJ94719.1 - 0.0052 16.3 0.0 0.0058 16.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase TSGP1 PF07771.11 CDJ94719.1 - 0.013 15.6 0.1 0.023 14.8 0.1 1.4 1 0 0 1 1 1 0 Tick salivary peptide group 1 Galactosyl_T PF01762.21 CDJ94721.1 - 1.5e-40 139.1 0.0 2e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase COX2_TM PF02790.15 CDJ94721.1 - 0.071 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain AP3D1 PF06375.11 CDJ94722.1 - 0.00017 21.8 15.1 0.0002 21.6 15.1 1.2 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 ETRAMP PF09716.10 CDJ94722.1 - 0.0068 16.4 6.3 0.0069 16.4 6.3 1.3 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) DUF4604 PF15377.6 CDJ94722.1 - 0.029 14.8 19.5 0.038 14.4 19.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) LYRIC PF15686.5 CDJ94722.1 - 0.055 13.0 17.3 0.067 12.7 17.3 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Spt20 PF12090.8 CDJ94722.1 - 0.14 11.7 12.5 0.19 11.3 12.5 1.1 1 0 0 1 1 1 0 Spt20 family RR_TM4-6 PF06459.12 CDJ94722.1 - 0.19 11.6 10.3 0.23 11.3 10.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TSGP1 PF07771.11 CDJ94722.1 - 0.36 11.0 14.4 0.7 10.1 14.4 1.5 1 0 0 1 1 1 0 Tick salivary peptide group 1 PTPRCAP PF15713.5 CDJ94722.1 - 0.45 10.8 5.6 0.28 11.5 4.0 1.4 1 1 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated EOS1 PF12326.8 CDJ94722.1 - 0.82 9.6 4.3 0.91 9.4 4.3 1.2 1 0 0 1 1 1 0 N-glycosylation protein DUF3899 PF13038.6 CDJ94722.1 - 1.1 9.7 3.6 1.9 9.1 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) DDHD PF02862.17 CDJ94722.1 - 1.2 9.3 6.3 1.5 9.0 6.3 1.2 1 0 0 1 1 1 0 DDHD domain NARP1 PF12569.8 CDJ94722.1 - 1.3 7.9 13.2 1.5 7.7 13.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TMEM214 PF10151.9 CDJ94722.1 - 1.4 7.3 13.5 1.4 7.3 13.5 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Peptidase_S49_N PF08496.10 CDJ94722.1 - 1.5 8.8 16.0 2.4 8.2 16.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SRP-alpha_N PF04086.13 CDJ94722.1 - 1.8 8.4 17.3 2.1 8.2 17.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ferlin_C PF16165.5 CDJ94722.1 - 2.1 8.3 12.7 4 7.4 12.7 1.5 1 0 0 1 1 1 0 Ferlin C-terminus Hydin_ADK PF17213.3 CDJ94722.1 - 3 8.1 8.8 3.8 7.7 8.8 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain OATP PF03137.20 CDJ94722.1 - 3.8 5.7 5.3 4.6 5.4 5.3 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family PRC2_HTH_1 PF18118.1 CDJ94722.1 - 4.5 8.1 12.7 1.9 9.3 10.0 1.7 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Presenilin PF01080.17 CDJ94722.1 - 5 5.8 9.7 5.6 5.6 9.7 1.1 1 0 0 1 1 1 0 Presenilin EMC3_TMCO1 PF01956.16 CDJ94722.1 - 9.7 5.9 9.6 14 5.3 9.6 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Tyrosinase PF00264.20 CDJ94723.1 - 2.5e-07 31.2 2.5 2.5e-07 31.2 2.5 2.3 2 1 0 2 2 2 1 Common central domain of tyrosinase DUF4363 PF14276.6 CDJ94725.1 - 0.65 10.1 3.3 5.2 7.2 0.2 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4363) Ras PF00071.22 CDJ94726.1 - 4.6e-42 143.4 0.0 5.6e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ94726.1 - 2.1e-11 44.1 0.0 3.6e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ94726.1 - 4.2e-07 29.6 0.0 5.3e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDJ94726.1 - 0.00024 20.7 0.1 0.00042 19.9 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF1366 PF07104.11 CDJ94726.1 - 0.0019 17.9 0.0 0.0044 16.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1366) G-alpha PF00503.20 CDJ94726.1 - 0.068 12.3 0.0 0.084 12.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit A2M_recep PF07677.14 CDJ94728.1 - 1.1e-18 67.8 0.1 1.3e-18 67.5 0.1 1.1 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain 7TM_GPCR_Srw PF10324.9 CDJ94731.1 - 1.2e-20 74.0 13.1 1.2e-20 74.0 13.1 1.4 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 CDJ94731.1 - 6.5e-19 68.3 16.8 6.5e-19 68.3 16.8 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) NOP19 PF10863.8 CDJ94731.1 - 0.033 14.0 0.1 0.06 13.2 0.1 1.3 1 0 0 1 1 1 0 Nucleolar protein 19 Gaa1 PF04114.14 CDJ94731.1 - 0.44 9.5 8.4 0.043 12.8 0.8 2.2 1 1 1 2 2 2 0 Gaa1-like, GPI transamidase component DUF4234 PF14018.6 CDJ94731.1 - 2.7 8.2 7.7 0.19 11.9 0.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) UPF0542 PF15086.6 CDJ94731.1 - 6.1 6.9 12.5 0.26 11.2 0.7 3.6 2 1 1 3 3 3 0 Uncharacterised protein family UPF0542 Pro_isomerase PF00160.21 CDJ94732.1 - 3.3e-50 170.4 0.3 1.2e-49 168.7 0.0 2.0 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 CDJ94732.1 - 1.5e-09 37.6 2.0 1.5e-09 37.6 2.0 2.3 2 1 0 2 2 2 1 Rtf2 RING-finger zf-Nse PF11789.8 CDJ94732.1 - 0.0078 16.0 0.3 0.64 9.9 0.2 2.7 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 CDJ94732.1 - 0.036 14.2 1.7 0.51 10.5 0.0 3.2 3 1 1 4 4 4 0 U-box domain zf-NOSIP PF15906.5 CDJ94732.1 - 0.046 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein DDE_Tnp_IS1595 PF12762.7 CDJ94732.1 - 0.094 12.7 0.6 0.3 11.1 0.6 1.9 1 1 0 1 1 1 0 ISXO2-like transposase domain FOXO_KIX_bdg PF16675.5 CDJ94732.1 - 0.1 12.9 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 KIX-binding domain of forkhead box O, CR2 DUF1467 PF07330.12 CDJ94734.1 - 0.024 14.5 0.0 2.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1467) RR_TM4-6 PF06459.12 CDJ94734.1 - 4.4 7.1 11.6 1.9 8.3 7.0 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF148 PF02520.17 CDJ94736.1 - 2.3e-24 85.6 7.3 2.7e-24 85.4 7.3 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF148 MAP65_ASE1 PF03999.12 CDJ94736.1 - 0.0019 17.0 3.3 0.0024 16.6 3.3 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) RmuC PF02646.16 CDJ94736.1 - 0.0088 15.2 1.2 0.012 14.8 1.2 1.2 1 0 0 1 1 1 1 RmuC family Baculo_PEP_C PF04513.12 CDJ94736.1 - 0.0094 16.0 0.0 0.012 15.6 0.0 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus MIF4G_like_2 PF09090.11 CDJ94736.1 - 0.018 14.5 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 MIF4G like DUF948 PF06103.11 CDJ94736.1 - 0.021 15.1 0.6 0.031 14.5 0.6 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 CDJ94736.1 - 0.033 14.2 2.2 0.046 13.8 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3437 PF11919.8 CDJ94736.1 - 0.035 14.0 0.6 0.31 11.0 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3437) Muted PF14942.6 CDJ94736.1 - 0.085 13.2 4.6 0.14 12.5 4.5 1.4 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein PHTB1_C PF14728.6 CDJ94736.1 - 0.17 11.0 3.6 0.21 10.7 3.6 1.1 1 0 0 1 1 1 0 PTHB1 C-terminus DUF3450 PF11932.8 CDJ94736.1 - 0.22 10.8 4.4 0.3 10.3 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CortBP2 PF09727.9 CDJ94736.1 - 0.4 10.6 5.3 0.99 9.3 5.2 1.6 1 1 0 1 1 1 0 Cortactin-binding protein-2 DUF4422 PF14393.6 CDJ94736.1 - 1.1 9.1 7.0 1.3 8.9 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4422) FliJ PF02050.16 CDJ94736.1 - 1.4 9.1 5.1 5 7.4 0.5 2.1 1 1 1 2 2 2 0 Flagellar FliJ protein DUF1043 PF06295.12 CDJ94736.1 - 2.1 8.3 7.7 4.5 7.3 7.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) zf-CCHC PF00098.23 CDJ94737.1 - 0.0083 16.2 5.7 0.0083 16.2 5.7 2.9 2 1 0 2 2 2 1 Zinc knuckle DUF241 PF03087.14 CDJ94737.1 - 0.011 15.6 1.0 0.02 14.7 1.0 1.4 1 0 0 1 1 1 0 Arabidopsis protein of unknown function DUF2205 PF10224.9 CDJ94737.1 - 0.37 10.8 5.4 0.2 11.7 0.6 2.4 2 0 0 2 2 2 0 Short coiled-coil protein HTH_Tnp_1 PF01527.20 CDJ94737.1 - 0.38 11.1 3.0 1 9.7 0.0 2.5 2 1 0 2 2 2 0 Transposase zf-CCHC_4 PF14392.6 CDJ94737.1 - 4.7 7.0 13.2 0.12 12.1 2.7 2.7 2 0 0 2 2 2 0 Zinc knuckle Pkinase PF00069.25 CDJ94739.1 - 1.5e-59 201.6 0.0 1e-58 198.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ94739.1 - 2.2e-31 109.1 0.0 1.1e-30 106.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ94739.1 - 9.9e-06 24.6 0.0 1.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDJ94739.1 - 0.00032 20.1 0.0 0.00055 19.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CDJ94739.1 - 0.0042 17.0 0.0 0.16 11.9 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family LPD24 PF18839.1 CDJ94739.1 - 0.015 15.5 0.5 0.25 11.6 0.4 2.8 2 1 0 2 2 2 0 Large polyvalent protein associated domain 24 SCVP PF17619.2 CDJ94740.1 - 4.8e-17 62.6 0.0 5.6e-17 62.4 0.0 1.0 1 0 0 1 1 1 1 Secreted clade V proteins TraF_2 PF13729.6 CDJ94740.1 - 0.1 12.0 0.0 0.11 11.8 0.0 1.0 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein SCVP PF17619.2 CDJ94741.1 - 2.5e-18 66.7 0.0 2.9e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 Secreted clade V proteins SCVP PF17619.2 CDJ94742.1 - 5e-27 94.6 0.1 8.3e-27 93.9 0.1 1.3 1 0 0 1 1 1 1 Secreted clade V proteins DUF3439 PF11921.8 CDJ94742.1 - 0.0028 17.6 9.3 0.0047 16.9 9.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 CDJ94742.1 - 0.18 9.8 4.0 0.21 9.5 4.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.11 CDJ94742.1 - 0.76 7.9 8.4 0.91 7.6 8.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Pkinase PF00069.25 CDJ94743.1 - 1e-24 87.3 0.0 1.2e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ94743.1 - 5.4e-12 45.6 0.0 6.9e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ94743.1 - 0.0043 17.0 0.0 2.6 7.9 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Globin PF00042.22 CDJ94744.1 - 2.3e-22 79.6 0.1 3.4e-22 79.1 0.1 1.3 1 0 0 1 1 1 1 Globin PHO4 PF01384.20 CDJ94746.1 - 1.1e-50 172.6 8.1 1.3e-50 172.4 8.1 1.0 1 0 0 1 1 1 1 Phosphate transporter family Ytca PF17090.5 CDJ94746.1 - 2.7 8.6 9.2 0.31 11.6 2.9 2.4 2 0 0 2 2 2 0 Uncharacterised protein family DUF4746 PF15928.5 CDJ94747.1 - 0.25 10.7 10.4 0.27 10.6 10.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RNA_pol_Rpc4 PF05132.14 CDJ94747.1 - 1.9 8.9 8.5 0.96 9.9 6.3 1.7 1 1 1 2 2 2 0 RNA polymerase III RPC4 Presenilin PF01080.17 CDJ94747.1 - 2.2 7.0 7.9 2.3 6.9 7.9 1.2 1 0 0 1 1 1 0 Presenilin zf-C3HC PF07967.13 CDJ94748.1 - 3e-13 49.9 0.9 4.8e-13 49.3 0.2 1.7 2 0 0 2 2 2 1 C3HC zinc finger-like BIR PF00653.21 CDJ94748.1 - 0.0066 17.1 1.6 0.071 13.8 0.4 2.3 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain Rsm1 PF08600.10 CDJ94748.1 - 0.2 11.8 7.3 4.3 7.5 0.3 3.6 2 2 0 2 2 2 0 Rsm1-like F-box PF00646.33 CDJ94752.1 - 0.013 15.3 0.0 0.044 13.7 0.0 1.8 1 0 0 1 1 1 0 F-box domain Fringe PF02434.16 CDJ94753.1 - 0.0012 18.3 0.1 0.0019 17.7 0.1 1.3 1 0 0 1 1 1 1 Fringe-like UDPGP PF01704.18 CDJ94755.1 - 4.8e-192 638.1 0.0 5.6e-192 637.9 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase FG-GAP_2 PF14312.6 CDJ94755.1 - 0.18 12.1 0.1 0.35 11.1 0.1 1.4 1 0 0 1 1 1 0 FG-GAP repeat CheR_N PF03705.15 CDJ94756.1 - 0.18 11.5 2.2 1.1 9.1 0.3 2.2 2 0 0 2 2 2 0 CheR methyltransferase, all-alpha domain RVT_1 PF00078.27 CDJ94757.1 - 3.5e-12 46.3 0.0 4.2e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CDJ94758.1 - 2.8e-05 23.7 0.0 8.5e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ISG65-75 PF11727.8 CDJ94758.1 - 0.16 11.1 3.1 0.27 10.4 3.1 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein Citrate_synt PF00285.21 CDJ94759.1 - 9.7e-105 350.6 0.0 1.2e-104 350.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain dsrm PF00035.26 CDJ94760.1 - 5.6e-19 68.6 0.8 4.2e-13 49.8 0.1 3.3 3 0 0 3 3 3 2 Double-stranded RNA binding motif DND1_DSRM PF14709.7 CDJ94760.1 - 0.00069 19.8 4.0 0.039 14.2 0.1 3.7 3 2 0 3 3 3 2 double strand RNA binding domain from DEAD END PROTEIN 1 AIP3 PF03915.13 CDJ94761.1 - 3.4e-13 49.5 9.3 8.1e-13 48.2 9.3 1.5 1 1 0 1 1 1 1 Actin interacting protein 3 DUF2353 PF09789.9 CDJ94761.1 - 0.025 13.9 0.7 0.057 12.8 0.7 1.5 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) NBD_C PF17042.5 CDJ94761.1 - 0.061 13.8 1.7 0.17 12.4 1.7 1.7 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain Syntaxin-6_N PF09177.11 CDJ94761.1 - 6.9 7.3 6.7 2.4 8.7 0.5 2.9 2 1 1 3 3 3 0 Syntaxin 6, N-terminal O-FucT PF10250.9 CDJ94762.1 - 1.8e-27 97.0 0.0 2.1e-27 96.7 0.0 1.0 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase TauD PF02668.16 CDJ94762.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.3 1 1 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family SCAN PF02023.17 CDJ94762.1 - 0.11 12.3 0.1 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 SCAN domain O-FucT PF10250.9 CDJ94763.1 - 7.3e-41 141.0 0.1 9.4e-26 91.3 0.0 2.7 2 1 1 3 3 3 2 GDP-fucose protein O-fucosyltransferase CRIC_ras_sig PF10534.9 CDJ94763.1 - 1.2e-13 51.1 1.2 1.9e-13 50.4 0.5 1.8 2 0 0 2 2 2 1 Connector enhancer of kinase suppressor of ras PDZ_6 PF17820.1 CDJ94763.1 - 6.3e-12 45.1 0.3 3.8e-11 42.7 0.1 2.4 3 0 0 3 3 3 1 PDZ domain PH PF00169.29 CDJ94763.1 - 8.2e-12 45.6 1.2 2.6e-11 44.0 1.2 2.0 1 0 0 1 1 1 1 PH domain SAM_1 PF00536.30 CDJ94763.1 - 5.9e-10 39.5 0.0 1.2e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ PF00595.24 CDJ94763.1 - 1.9e-09 37.8 0.0 3.5e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain SAM_2 PF07647.17 CDJ94763.1 - 2.2e-06 27.7 0.0 5.1e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ_2 PF13180.6 CDJ94763.1 - 0.0035 17.6 0.0 0.009 16.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain COX1 PF00115.20 CDJ94763.1 - 0.011 14.7 0.1 3.8 6.2 0.0 2.1 2 0 0 2 2 2 0 Cytochrome C and Quinol oxidase polypeptide I PH_13 PF16652.5 CDJ94763.1 - 0.022 14.6 1.8 0.024 14.4 0.1 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Polyketide_cyc PF03364.20 CDJ94763.1 - 0.42 10.8 4.3 16 5.7 0.3 2.6 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport Y_phosphatase3 PF13350.6 CDJ94764.1 - 0.011 15.7 0.0 0.033 14.2 0.0 1.9 1 0 0 1 1 1 0 Tyrosine phosphatase family IpgD PF05925.12 CDJ94764.1 - 0.17 10.4 0.0 0.46 9.0 0.0 1.7 2 0 0 2 2 2 0 Enterobacterial virulence protein IpgD BBL5 PF07289.11 CDJ94765.1 - 1.1e-138 461.8 0.0 1.3e-138 461.6 0.0 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein bPH_3 PF14470.6 CDJ94765.1 - 0.00018 21.8 0.0 0.0091 16.3 0.0 2.3 2 0 0 2 2 2 1 Bacterial PH domain Vps36_ESCRT-II PF11605.8 CDJ94765.1 - 0.015 15.5 0.0 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 Voldacs PF03517.13 CDJ94765.1 - 0.032 14.4 4.2 18 5.4 0.1 3.4 3 1 0 3 3 3 0 Regulator of volume decrease after cellular swelling MetW PF07021.12 CDJ94766.1 - 0.1 12.2 0.0 8.9 5.9 0.0 2.1 1 1 1 2 2 2 0 Methionine biosynthesis protein MetW Integrin_alpha2 PF08441.12 CDJ94767.1 - 2.1e-80 270.9 0.0 2.6e-80 270.6 0.0 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 CDJ94767.1 - 4.1e-19 68.4 24.2 4.1e-10 39.6 6.0 4.2 3 0 0 3 3 3 3 FG-GAP repeat VCBS PF13517.6 CDJ94767.1 - 7.3e-08 32.9 4.6 0.0067 17.0 0.2 3.2 1 1 2 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella LYRIC PF15686.5 CDJ94767.1 - 0.033 13.8 0.2 0.059 12.9 0.2 1.3 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Integrin_alpha PF00357.20 CDJ94767.1 - 0.57 10.3 3.6 1.8 8.8 3.6 1.9 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region FG-GAP_2 PF14312.6 CDJ94767.1 - 9.9 6.5 25.8 7.1 7.0 0.7 5.8 6 0 0 6 6 6 0 FG-GAP repeat RRM_1 PF00076.22 CDJ94768.1 - 0.00012 21.8 0.1 0.00026 20.8 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.22 CDJ94770.1 - 2.2e-12 46.9 0.1 2.5e-12 46.7 0.1 1.1 1 0 0 1 1 1 1 Ras family UCH PF00443.29 CDJ94773.1 - 1.5e-72 244.2 0.0 2e-72 243.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ94773.1 - 1.2e-11 44.8 2.5 4.6e-08 33.0 0.1 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 CDJ94773.1 - 4.3e-08 33.7 0.0 1.4e-07 32.0 0.0 2.0 1 0 0 1 1 1 1 DUSP domain NFRKB_winged PF14465.6 CDJ94773.1 - 0.0048 17.1 0.2 0.036 14.3 0.1 2.3 2 0 0 2 2 2 1 NFRKB Winged Helix-like Knl1_RWD_C PF18210.1 CDJ94773.1 - 0.028 14.9 0.1 0.35 11.4 0.1 2.6 3 0 0 3 3 3 0 Knl1 RWD C-terminal domain zf-C6H2 PF15801.5 CDJ94773.1 - 0.22 11.9 3.3 1.1 9.6 0.7 2.5 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-MIZ PF02891.20 CDJ94773.1 - 1 9.2 4.2 1.1 9.1 0.4 2.6 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger PHD PF00628.29 CDJ94773.1 - 3.6 7.5 4.8 0.86 9.5 1.0 1.9 2 0 0 2 2 2 0 PHD-finger G-alpha PF00503.20 CDJ94774.1 - 1.7e-103 346.5 6.1 1.9e-103 346.3 6.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDJ94774.1 - 1.1e-11 44.5 0.4 3.8e-11 42.7 0.2 2.1 2 1 0 2 2 2 1 ADP-ribosylation factor family DUF503 PF04456.12 CDJ94774.1 - 0.053 13.4 0.4 0.93 9.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF503) UbiA PF01040.18 CDJ94775.1 - 5.4e-24 84.9 12.3 6.6e-24 84.6 12.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family BACK PF07707.15 CDJ94776.1 - 4e-25 87.9 2.2 4e-25 87.9 2.2 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 CDJ94776.1 - 1.4e-10 41.4 0.1 2.8e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.25 CDJ94776.1 - 6.1e-06 25.7 0.7 0.047 13.3 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 CDJ94776.1 - 0.00046 20.4 0.1 1.1 9.7 0.0 2.6 1 1 1 2 2 2 2 Kelch motif Kelch_3 PF13415.6 CDJ94776.1 - 0.16 12.3 0.4 3.5 8.0 0.0 2.5 3 0 0 3 3 3 0 Galactose oxidase, central domain GDPD PF03009.17 CDJ94777.1 - 5.7e-33 114.7 0.1 7.5e-33 114.3 0.1 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Phos_pyr_kin PF08543.12 CDJ94777.1 - 0.09 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Myosin_head PF00063.21 CDJ94778.1 - 6.5e-138 460.9 0.3 7.4e-138 460.7 0.3 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 CDJ94778.1 - 0.0024 18.3 0.0 0.0068 16.8 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CDJ94778.1 - 0.033 14.4 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CDJ94778.1 - 0.035 13.8 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF2075 PF09848.9 CDJ94778.1 - 0.048 12.9 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATP_bind_2 PF03668.15 CDJ94778.1 - 0.055 12.7 0.1 0.25 10.6 0.1 1.9 2 0 0 2 2 2 0 P-loop ATPase protein family CbiA PF01656.23 CDJ94778.1 - 0.062 13.4 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 CDJ94778.1 - 0.097 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_10 PF12846.7 CDJ94778.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ABC_tran PF00005.27 CDJ94778.1 - 0.11 13.0 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 CDJ94778.1 - 0.13 12.8 0.0 0.37 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CDJ94778.1 - 0.14 12.1 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RVT_1 PF00078.27 CDJ94779.1 - 1.2e-39 136.1 0.0 1.3e-39 136.0 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) VEG PF06257.11 CDJ94780.1 - 0.029 14.4 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Biofilm formation stimulator VEG zf-RING_UBOX PF13445.6 CDJ94782.1 - 1.2e-06 28.4 3.2 1.2e-06 28.4 3.2 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 CDJ94782.1 - 2.5e-06 27.7 7.5 2.5e-06 27.7 7.5 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 CDJ94782.1 - 8.6e-05 22.4 5.8 8.6e-05 22.4 5.8 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CDJ94782.1 - 0.0006 19.6 6.2 0.0006 19.6 6.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ94782.1 - 0.0009 19.3 7.7 0.0009 19.3 7.7 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 CDJ94782.1 - 0.0024 17.8 4.1 0.0046 16.9 3.1 2.0 1 1 1 2 2 2 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_2 PF13923.6 CDJ94782.1 - 0.012 15.5 4.5 0.012 15.5 4.5 2.1 2 1 1 3 3 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CDJ94782.1 - 0.36 11.0 4.3 0.92 9.7 4.3 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 CDJ94782.1 - 0.51 10.2 12.4 0.17 11.7 7.6 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CDJ94782.1 - 1.1 9.7 5.3 3.7 7.9 5.4 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain FANCL_C PF11793.8 CDJ94782.1 - 6.4 7.0 7.9 0.19 11.9 1.4 1.8 2 0 0 2 2 1 0 FANCL C-terminal domain zf-U1 PF06220.12 CDJ94782.1 - 7 6.5 8.3 0.68 9.7 3.4 1.9 2 0 0 2 2 2 0 U1 zinc finger Peptidase_S9 PF00326.21 CDJ94783.1 - 9.1e-41 139.7 0.0 2e-40 138.6 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CDJ94783.1 - 4.4e-11 42.9 0.5 4.9e-06 26.4 0.2 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ94783.1 - 3.1e-10 39.7 0.5 1.3e-05 24.5 0.2 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 CDJ94783.1 - 7.1e-09 35.5 0.1 2.1e-08 34.0 0.1 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 CDJ94783.1 - 2.4e-08 33.9 0.0 0.00025 20.7 0.0 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 CDJ94783.1 - 7e-05 23.5 0.5 0.00047 20.8 0.5 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.14 CDJ94783.1 - 0.0083 15.5 0.1 0.015 14.6 0.1 1.3 1 0 0 1 1 1 1 Secretory lipase PAF-AH_p_II PF03403.13 CDJ94783.1 - 0.0092 14.5 0.0 0.058 11.9 0.0 2.0 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II BAAT_C PF08840.11 CDJ94783.1 - 0.013 15.4 0.0 0.11 12.4 0.0 2.1 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 CDJ94783.1 - 0.045 13.4 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF2920 PF11144.8 CDJ94783.1 - 0.079 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Abhydrolase_3 PF07859.13 CDJ94783.1 - 0.12 12.2 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold FRB_dom PF08771.11 CDJ94784.1 - 0.0025 18.2 0.2 0.0038 17.6 0.2 1.4 1 1 0 1 1 1 1 FKBP12-rapamycin binding domain Mis14 PF08641.12 CDJ94784.1 - 0.012 15.9 3.3 0.015 15.6 3.3 1.2 1 0 0 1 1 1 0 Kinetochore protein Mis14 like Hormone_2 PF00123.20 CDJ94784.1 - 0.1 12.5 0.2 20 5.2 0.1 2.4 2 0 0 2 2 2 0 Peptide hormone SR-25 PF10500.9 CDJ94785.1 - 1.4 8.5 14.5 0.45 10.1 5.3 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SMAP PF15477.6 CDJ94786.1 - 9e-16 58.6 0.3 9e-16 58.6 0.3 3.2 3 1 0 3 3 3 1 Small acidic protein family DEAD PF00270.29 CDJ94788.1 - 3.1e-18 66.2 0.0 6.4e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ94788.1 - 9.1e-16 58.2 0.0 3.4e-14 53.1 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.10 CDJ94788.1 - 2.4e-15 56.3 0.1 5.1e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 CDJ94788.1 - 2.8e-14 52.9 0.0 7.9e-14 51.4 0.0 1.8 1 0 0 1 1 1 1 HRDC domain RecQ_Zn_bind PF16124.5 CDJ94788.1 - 5.6e-14 52.6 2.3 5.6e-14 52.6 2.3 2.5 3 0 0 3 3 3 1 RecQ zinc-binding ResIII PF04851.15 CDJ94788.1 - 0.00015 21.8 0.0 0.00032 20.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Protoglobin PF11563.8 CDJ94788.1 - 0.026 14.4 0.0 0.078 12.9 0.0 1.7 1 0 0 1 1 1 0 Protoglobin DUF934 PF06073.12 CDJ94788.1 - 0.15 12.0 0.0 0.5 10.3 0.0 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF934) Anillin PF08174.11 CDJ94789.1 - 6.1e-17 62.4 0.0 2e-16 60.7 0.0 2.0 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 CDJ94789.1 - 4e-06 27.3 0.1 1.6e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 PH domain Spc110_C PF18520.1 CDJ94789.1 - 0.098 12.3 0.1 0.24 11.0 0.1 1.7 1 0 0 1 1 1 0 Spindle pole body component 110 C-terminal domain Anillin_N PF16018.5 CDJ94789.1 - 0.22 12.1 6.6 0.089 13.4 2.3 2.7 2 0 0 2 2 2 0 Anillin N-terminus Collagen PF01391.18 CDJ94790.1 - 5.5e-27 93.3 88.8 3.7e-09 36.2 26.1 4.2 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ94790.1 - 1.5e-11 44.2 0.1 2e-11 43.7 0.1 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain RNB PF00773.19 CDJ94791.1 - 3.5e-33 115.3 0.3 9.7e-33 113.9 0.1 1.8 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 CDJ94791.1 - 2.7e-19 69.0 0.0 5.6e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 CDJ94791.1 - 4e-10 39.7 0.0 1.7e-07 31.3 0.0 2.6 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 CDJ94791.1 - 2.4e-06 27.3 0.0 8.5e-06 25.6 0.0 2.0 1 0 0 1 1 1 1 Rrp44-like cold shock domain OB_RNB PF08206.11 CDJ94791.1 - 0.0014 18.3 0.0 0.0033 17.1 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease B OB domain RVT_1 PF00078.27 CDJ94791.1 - 0.0069 15.9 0.1 0.015 14.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) fn3 PF00041.21 CDJ94792.1 - 4.8e-19 68.5 1.5 6.9e-08 32.7 0.2 3.4 3 0 0 3 3 3 3 Fibronectin type III domain Pkinase PF00069.25 CDJ94794.1 - 1.4e-66 224.6 0.0 3.1e-66 223.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ94794.1 - 1.2e-32 113.2 0.0 2.5e-32 112.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ94794.1 - 4.4e-05 22.9 0.0 0.11 11.8 0.0 2.4 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 CDJ94794.1 - 0.0031 17.5 0.1 0.085 12.8 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ94794.1 - 0.036 13.4 0.1 0.077 12.3 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aldolase_II PF00596.21 CDJ94795.1 - 5.6e-29 101.4 0.0 6.7e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Phage_antitermQ PF06530.12 CDJ94798.1 - 0.013 15.4 0.2 0.027 14.4 0.2 1.6 1 0 0 1 1 1 0 Phage antitermination protein Q PS_Dcarbxylase PF02666.15 CDJ94800.1 - 4.4e-57 192.9 0.0 5e-57 192.7 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase SRP68 PF16969.5 CDJ94801.1 - 0.44 9.5 0.5 0.53 9.2 0.5 1.1 1 0 0 1 1 1 0 RNA-binding signal recognition particle 68 HCV_NS5a PF01506.19 CDJ94801.1 - 5.8 6.9 6.5 6.4 6.8 4.7 1.9 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a protein membrane anchor DNTTIP1_dimer PF18192.1 CDJ94802.1 - 0.074 13.4 0.2 0.36 11.2 0.1 2.1 2 0 0 2 2 2 0 DNTTIP1 dimerisation domain Alpha-amylase PF00128.24 CDJ94803.1 - 1.2e-35 123.6 0.1 2.4e-35 122.7 0.1 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain SLC3A2_N PF16028.5 CDJ94803.1 - 9.2e-21 73.2 0.4 1.6e-20 72.4 0.4 1.4 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus 7TM_GPCR_Srd PF10317.9 CDJ94805.1 - 1.4e-05 24.5 0.7 1.6e-05 24.3 0.7 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd Scm3 PF10384.9 CDJ94806.1 - 0.14 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Centromere protein Scm3 7TM_GPCR_Srd PF10317.9 CDJ94807.1 - 1.2e-43 149.4 21.2 1.5e-43 149.1 21.2 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Str PF10326.9 CDJ94807.1 - 2.1e-09 37.2 24.2 3.1e-08 33.3 24.2 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srj PF10319.9 CDJ94807.1 - 3.5e-08 33.2 6.6 3.5e-08 33.2 6.6 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Srh PF10318.9 CDJ94807.1 - 1e-05 24.7 24.6 1.7e-05 24.0 24.6 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Sri PF10327.9 CDJ94807.1 - 7.4e-05 22.1 17.1 9.5e-05 21.7 17.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri 7TM_GPCR_Srd PF10317.9 CDJ94808.1 - 4.4e-43 147.6 25.0 4.9e-43 147.4 25.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Str PF10326.9 CDJ94808.1 - 5.1e-09 35.9 14.4 5.1e-09 35.9 14.4 2.0 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srj PF10319.9 CDJ94808.1 - 2.7e-08 33.5 8.5 2.7e-08 33.5 8.5 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Sri PF10327.9 CDJ94808.1 - 2.7e-06 26.8 18.1 3.7e-06 26.3 18.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri 7TM_GPCR_Srh PF10318.9 CDJ94808.1 - 3.2e-05 23.1 22.2 4.7e-05 22.6 22.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh DUF4602 PF15375.6 CDJ94809.1 - 5.8e-12 46.1 7.8 6.8e-12 45.9 7.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4602) HTH_48 PF17906.1 CDJ94810.1 - 1.2e-17 63.7 1.0 2.3e-17 62.8 1.0 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_38 PF13936.6 CDJ94810.1 - 2.6e-06 27.1 0.1 5.6e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 CDJ94810.1 - 1.5e-05 24.6 0.0 0.011 15.5 0.0 2.6 2 0 0 2 2 2 2 Homeodomain-like domain HTH_Tnp_IS630 PF01710.16 CDJ94810.1 - 1.9e-05 24.7 0.0 2.3e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 CDJ94810.1 - 4.2e-05 24.1 0.0 5.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 CDJ94810.1 - 6.3e-05 23.1 1.2 8.6e-05 22.7 0.3 1.6 2 0 0 2 2 2 1 Transposase HTH_50 PF18024.1 CDJ94810.1 - 0.00026 20.5 0.6 0.00046 19.7 0.0 1.6 2 0 0 2 2 1 1 Helix-turn-helix domain HTH_28 PF13518.6 CDJ94810.1 - 0.0003 20.8 0.0 0.45 10.7 0.0 2.6 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_11 PF08279.12 CDJ94810.1 - 0.0067 16.4 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 HTH domain TnsD PF15978.5 CDJ94810.1 - 0.0081 15.2 0.0 0.0085 15.1 0.0 1.2 1 0 0 1 1 1 1 Tn7-like transposition protein D HTH_Tnp_1 PF01527.20 CDJ94810.1 - 0.0082 16.4 0.2 5.6 7.4 0.1 2.2 1 1 1 2 2 2 2 Transposase IF2_N PF04760.15 CDJ94810.1 - 0.023 14.5 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region HTH_29 PF13551.6 CDJ94810.1 - 0.038 14.0 0.1 0.28 11.2 0.0 2.1 1 1 1 2 2 2 0 Winged helix-turn helix HTH_36 PF13730.6 CDJ94810.1 - 0.063 13.2 0.0 0.18 11.8 0.0 1.9 2 1 1 3 3 3 0 Helix-turn-helix domain HTH_6 PF01418.17 CDJ94810.1 - 0.09 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_Tnp_ISL3 PF13542.6 CDJ94810.1 - 0.093 12.2 0.2 0.38 10.2 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_10 PF04967.12 CDJ94810.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain HTH_5 PF01022.20 CDJ94810.1 - 0.13 12.1 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family NUMOD1 PF07453.13 CDJ94810.1 - 0.15 12.3 0.1 0.29 11.4 0.1 1.4 1 0 0 1 1 1 0 NUMOD1 domain RRM_1 PF00076.22 CDJ94811.1 - 2e-20 72.4 0.1 4.5e-20 71.2 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDJ94811.1 - 0.0027 17.7 0.0 0.0051 16.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_8 PF11835.8 CDJ94811.1 - 0.0068 16.6 0.1 0.077 13.2 0.0 2.5 2 1 1 3 3 3 1 RRM-like domain YebO PF13974.6 CDJ94812.1 - 0.62 10.2 5.3 1.4 9.1 5.3 1.6 1 0 0 1 1 1 0 YebO-like protein GAS PF13851.6 CDJ94812.1 - 1 8.7 17.7 0.47 9.8 14.6 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-O PF09496.10 CDJ94812.1 - 1.2 9.0 5.1 6.5 6.7 5.2 1.9 1 1 0 1 1 1 0 Cenp-O kinetochore centromere component Fib_alpha PF08702.10 CDJ94812.1 - 2.2 8.5 10.7 2 8.6 2.4 3.0 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family SpoIIIAH PF12685.7 CDJ94812.1 - 2.4 8.0 10.4 4.4 7.1 10.4 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein Peptidase_A17 PF05380.13 CDJ94813.1 - 1.2e-43 149.0 1.3 2.5e-43 147.9 1.3 1.6 1 0 0 1 1 1 1 Pao retrotransposon peptidase DUF1759 PF03564.15 CDJ94813.1 - 4.4e-24 85.1 1.3 4.4e-24 85.1 1.3 2.6 4 0 0 4 4 4 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 CDJ94813.1 - 5.4e-09 36.0 0.0 2.9e-08 33.7 0.0 2.2 2 0 0 2 2 2 1 Putative peptidase (DUF1758) RVT_1 PF00078.27 CDJ94813.1 - 0.00011 21.8 0.1 0.0006 19.4 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CDJ94813.1 - 0.00016 22.3 0.0 0.00046 20.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ94813.1 - 0.00022 21.7 0.2 0.00092 19.7 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ94813.1 - 0.0017 18.2 0.0 0.0041 16.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease NUDIX PF00293.28 CDJ94814.1 - 5.9e-11 42.5 0.1 9.1e-11 41.9 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain NPL4 PF05021.15 CDJ94815.1 - 1.2e-114 382.8 0.0 1.8e-114 382.3 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 CDJ94815.1 - 3.7e-56 189.3 1.3 8.3e-56 188.2 1.3 1.6 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region zf-RanBP PF00641.18 CDJ94815.1 - 0.0072 15.6 2.0 0.0072 15.6 2.0 2.4 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 CDJ94815.1 - 0.27 10.7 4.8 2.6 7.5 4.8 2.4 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain FSH1 PF03959.13 CDJ94816.1 - 2.2e-11 43.9 0.0 3.2e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DnaJ_C PF01556.18 CDJ94817.1 - 1.3e-44 151.8 0.1 1.8e-44 151.4 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CDJ94817.1 - 2.4e-28 98.0 2.3 3.7e-28 97.4 2.3 1.3 1 0 0 1 1 1 1 DnaJ domain Acyl-CoA_dh_1 PF00441.24 CDJ94818.1 - 1.8e-30 106.2 0.1 2.7e-30 105.6 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CDJ94818.1 - 2.3e-24 86.2 0.0 4.6e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CDJ94818.1 - 1.6e-20 73.1 0.0 2.8e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CDJ94818.1 - 1.1e-07 32.2 0.0 2.2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RhoGAP PF00620.27 CDJ94819.1 - 2.3e-25 89.2 0.0 3.9e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PDZ PF00595.24 CDJ94819.1 - 2.2e-06 27.9 0.3 5e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 PDZ domain C2 PF00168.30 CDJ94819.1 - 2.5e-05 24.5 0.0 5.1e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain PDZ_6 PF17820.1 CDJ94819.1 - 0.00087 19.1 0.1 0.0025 17.6 0.1 1.8 1 0 0 1 1 1 1 PDZ domain GST_C_3 PF14497.6 CDJ94820.1 - 1.2e-18 67.1 0.3 1.9e-18 66.4 0.3 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CDJ94820.1 - 2.2e-12 47.1 0.0 5.1e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CDJ94820.1 - 1.1e-07 31.9 0.4 3.2e-07 30.5 0.4 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDJ94820.1 - 9.1e-05 22.8 0.0 0.00018 21.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 CDJ94820.1 - 0.00053 20.7 0.0 0.0009 19.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 CDJ94820.1 - 0.0034 17.4 0.0 0.0077 16.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CDJ94820.1 - 0.027 14.8 0.0 0.05 13.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 CDJ94820.1 - 0.028 14.7 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.6 CDJ94821.1 - 8.1e-14 51.6 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CDJ94821.1 - 3.4e-12 46.5 0.0 6.9e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CDJ94821.1 - 4.1e-09 36.6 0.1 1.3e-08 34.9 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDJ94821.1 - 0.00012 22.4 0.0 0.00053 20.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDJ94821.1 - 0.00044 20.2 0.0 0.001 19.1 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 CDJ94821.1 - 0.0036 18.0 0.0 0.0066 17.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.6 CDJ94821.1 - 0.02 15.2 0.0 0.077 13.3 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 CDJ94821.1 - 0.05 13.9 0.0 0.078 13.3 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein CX PF01705.19 CDJ94822.1 - 6.5e-06 26.6 6.4 1.2e-05 25.7 6.4 1.4 1 0 0 1 1 1 1 CX module GST_C_3 PF14497.6 CDJ94823.1 - 9.1e-16 57.9 0.1 2.8e-15 56.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CDJ94823.1 - 6.4e-13 48.8 0.0 1.3e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CDJ94823.1 - 5e-08 33.0 0.2 1.9e-07 31.2 0.2 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDJ94823.1 - 2.5e-05 24.6 0.0 8.3e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDJ94823.1 - 0.00018 21.8 0.0 0.00061 20.1 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 CDJ94823.1 - 0.00025 21.7 0.0 0.00057 20.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 CDJ94823.1 - 0.049 13.7 0.1 0.08 13.0 0.1 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDJ94824.1 - 1.2e-13 51.1 0.1 2.6e-13 50.0 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CDJ94824.1 - 7.9e-13 48.5 0.0 2.2e-12 47.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CDJ94824.1 - 8.8e-07 29.1 0.1 2.6e-06 27.6 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDJ94824.1 - 8.9e-05 22.8 0.0 0.00027 21.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 CDJ94824.1 - 0.0046 17.7 0.0 0.0085 16.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.6 CDJ94824.1 - 0.021 15.1 0.0 0.045 14.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 CDJ94824.1 - 0.19 12.1 0.0 0.3 11.4 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_N PF02798.20 CDJ94825.1 - 3.1e-15 56.3 0.0 6.5e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CDJ94825.1 - 4.6e-15 55.6 0.1 2e-14 53.5 0.1 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDJ94825.1 - 1.2e-06 28.7 0.2 2.7e-06 27.5 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDJ94825.1 - 1.4e-05 25.4 0.0 4.3e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDJ94825.1 - 0.0022 18.2 0.0 0.0045 17.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 CDJ94825.1 - 0.0035 18.0 0.0 0.0066 17.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Peptidase_M2 PF01401.18 CDJ94825.1 - 0.034 12.8 0.0 0.042 12.5 0.0 1.1 1 0 0 1 1 1 0 Angiotensin-converting enzyme GST_C_3 PF14497.6 CDJ94826.1 - 5.1e-17 61.9 0.1 9.7e-17 61.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CDJ94826.1 - 6.6e-11 42.4 0.0 1.8e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CDJ94826.1 - 6.8e-09 35.8 0.1 2.2e-08 34.2 0.1 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDJ94826.1 - 0.00019 21.8 0.0 0.00036 20.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDJ94826.1 - 0.001 19.1 0.0 0.0028 17.6 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CDJ94826.1 - 0.001 19.3 0.0 0.0024 18.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 CDJ94826.1 - 0.064 14.0 0.0 0.18 12.6 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 CDJ94827.1 - 1.4e-14 54.0 0.1 2.4e-14 53.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CDJ94827.1 - 8.7e-13 48.4 0.0 2.1e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CDJ94827.1 - 2.8e-09 37.1 0.0 4.6e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDJ94827.1 - 2.5e-05 24.6 0.0 6.9e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 CDJ94827.1 - 0.00091 19.9 0.0 0.0017 19.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.6 CDJ94827.1 - 0.0034 17.7 0.0 0.0073 16.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 CDJ94827.1 - 0.0059 16.9 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 CDJ94827.1 - 0.082 12.9 0.1 0.27 11.3 0.0 2.1 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain BTB_3 PF16017.5 CDJ94828.1 - 4e-39 133.0 0.0 6.3e-39 132.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 CDJ94828.1 - 0.0032 17.8 0.0 0.0066 16.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain WLM PF08325.10 CDJ94828.1 - 0.0089 16.1 2.4 0.17 12.0 0.2 2.5 2 0 0 2 2 2 1 WLM domain SURF1 PF02104.15 CDJ94829.1 - 9.2e-40 136.7 0.0 1.2e-39 136.4 0.0 1.1 1 0 0 1 1 1 1 SURF1 family MCLC PF05934.11 CDJ94830.1 - 0.063 12.0 0.1 0.082 11.6 0.1 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) AA_permease_2 PF13520.6 CDJ94831.1 - 3.1e-14 52.6 16.0 4.9e-14 52.0 16.1 1.2 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CDJ94831.1 - 1.2e-07 30.8 15.7 1.6e-07 30.3 15.7 1.1 1 0 0 1 1 1 1 Amino acid permease CBP_BcsG PF11658.8 CDJ94831.1 - 1.4 7.2 6.5 0.27 9.6 3.0 1.6 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsG Spermine_synth PF01564.17 CDJ94836.1 - 3.4e-07 29.9 0.1 5.8e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_31 PF13847.6 CDJ94836.1 - 0.00024 20.9 0.1 0.00064 19.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ94836.1 - 0.002 18.8 0.0 0.0044 17.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ94836.1 - 0.0023 18.6 0.0 0.0073 16.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CDJ94836.1 - 0.013 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 CDJ94836.1 - 0.023 14.2 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_15 PF09445.10 CDJ94836.1 - 0.071 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_12 PF08242.12 CDJ94836.1 - 0.15 12.8 0.0 0.31 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CHGN PF05679.16 CDJ94837.1 - 5.9e-114 381.7 0.0 6.9e-114 381.5 0.0 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 CDJ94837.1 - 0.00046 19.7 0.0 0.00088 18.8 0.0 1.5 1 0 0 1 1 1 1 Fringe-like Cullin PF00888.22 CDJ94838.1 - 1.1e-162 542.9 0.1 1.3e-162 542.7 0.1 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CDJ94838.1 - 2.5e-26 91.5 4.7 5.9e-26 90.3 2.6 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain HbrB PF08539.11 CDJ94838.1 - 0.008 16.2 0.6 0.041 13.9 0.0 2.5 3 0 0 3 3 3 1 HbrB-like IBN_N PF03810.19 CDJ94839.1 - 0.0056 16.6 0.1 0.083 12.8 0.0 2.3 1 1 1 2 2 2 1 Importin-beta N-terminal domain Glyco_transf_92 PF01697.27 CDJ94840.1 - 9.3e-43 146.8 1.5 9.3e-43 146.8 1.5 1.4 2 0 0 2 2 2 1 Glycosyltransferase family 92 QVR PF17064.5 CDJ94841.1 - 0.046 14.0 13.2 0.065 13.5 13.2 1.2 1 0 0 1 1 1 0 Sleepless protein Ion_trans PF00520.31 CDJ94842.1 - 8.4e-13 48.1 3.4 1.1e-12 47.7 3.4 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CDJ94842.1 - 0.058 13.4 0.9 0.058 13.4 0.9 2.1 2 0 0 2 2 2 0 Ion channel Pkinase PF00069.25 CDJ94843.1 - 2.7e-57 194.1 0.0 6.6e-57 192.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ94843.1 - 6.8e-45 153.4 0.0 1.4e-44 152.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 CDJ94843.1 - 4.8e-16 58.7 3.8 4.8e-16 58.7 3.8 3.3 3 0 0 3 3 3 2 Oxidative-stress-responsive kinase 1 C-terminal domain DUF1676 PF07898.13 CDJ94843.1 - 6.6 6.7 8.7 16 5.5 8.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) HTH_48 PF17906.1 CDJ94844.1 - 3.3e-14 52.7 0.0 4.6e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 HTH domain in Mos1 transposase 7TM_GPCR_Srsx PF10320.9 CDJ94845.1 - 1.5e-05 24.6 6.1 1.5e-05 24.6 6.1 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx Ni_hydr_CYTB PF01292.20 CDJ94845.1 - 0.044 13.4 0.1 4 7.0 0.0 2.5 2 1 1 3 3 3 0 Prokaryotic cytochrome b561 DUF5325 PF17259.2 CDJ94845.1 - 0.4 10.6 0.1 0.4 10.6 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5325) Mito_carr PF00153.27 CDJ94850.1 - 6.9e-33 112.4 0.1 9.4e-17 60.7 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Mito_carr PF00153.27 CDJ94851.1 - 8.9e-11 41.6 0.1 1e-10 41.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein RSN1_TM PF13967.6 CDJ94852.1 - 0.0074 16.0 0.3 0.009 15.8 0.3 1.1 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport Amnionless PF14828.6 CDJ94852.1 - 0.033 13.0 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 Amnionless DUF1980 PF09323.10 CDJ94852.1 - 0.093 12.6 0.0 0.1 12.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Syndecan PF01034.20 CDJ94852.1 - 0.16 11.9 2.4 0.25 11.3 2.4 1.3 1 0 0 1 1 1 0 Syndecan domain DUF347 PF03988.12 CDJ94852.1 - 0.2 11.9 1.6 0.27 11.5 1.6 1.2 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) 7tm_1 PF00001.21 CDJ94853.1 - 5e-22 78.5 6.0 1.1e-21 77.4 6.0 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Glyco_hydro_62 PF03664.13 CDJ94853.1 - 0.076 12.3 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 62 Ig_3 PF13927.6 CDJ94854.1 - 1.1e-07 32.3 0.0 2.1e-05 25.1 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 CDJ94854.1 - 3.3e-07 30.3 0.0 4.6e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin I-set domain C2-set_2 PF08205.12 CDJ94854.1 - 0.0056 16.7 0.0 0.23 11.6 0.0 2.1 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 CDJ94854.1 - 0.031 14.6 0.0 0.37 11.2 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin domain ig PF00047.25 CDJ94854.1 - 0.059 13.5 0.0 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 Immunoglobulin domain Bromo_TP PF07524.13 CDJ94856.1 - 0.064 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Bromodomain associated CARMIL_C PF16000.5 CDJ94856.1 - 0.11 12.1 8.2 0.16 11.5 8.2 1.4 1 0 0 1 1 1 0 CARMIL C-terminus VPS28 PF03997.12 CDJ94856.1 - 0.53 9.9 2.4 1.1 8.9 0.0 2.5 3 1 0 3 3 3 0 VPS28 protein DUF2431 PF10354.9 CDJ94858.1 - 2.7e-33 115.6 0.0 1.2e-32 113.5 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) Methyltransf_4 PF02390.17 CDJ94858.1 - 0.041 13.4 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Ras PF00071.22 CDJ94859.1 - 2.9e-26 92.0 0.1 3.7e-26 91.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ94859.1 - 1.2e-07 31.9 0.2 2.5e-07 31.0 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ94859.1 - 0.0023 17.4 0.1 0.0031 17.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family HUN PF08729.10 CDJ94860.1 - 3.1e-17 62.3 5.1 7.4e-17 61.1 5.1 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain EccE PF11203.8 CDJ94860.1 - 0.2 12.0 4.8 0.22 11.9 1.0 3.0 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE SET PF00856.28 CDJ94861.1 - 0.00017 22.0 0.0 0.0011 19.3 0.0 2.2 1 1 0 1 1 1 1 SET domain DUF5623 PF18536.1 CDJ94861.1 - 0.077 13.3 0.0 8.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5623) TMEM132 PF16070.5 CDJ94862.1 - 6.3e-82 275.7 0.5 8.2e-82 275.3 0.5 1.1 1 0 0 1 1 1 1 Transmembrane protein family 132 Baseplate PF16774.5 CDJ94862.1 - 0.1 12.5 0.6 0.28 11.1 0.1 1.9 2 0 0 2 2 2 0 Baseplate protein B56 PF01603.20 CDJ94863.1 - 2.5e-52 178.3 1.1 2.9e-52 178.1 1.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) zf-C2H2 PF00096.26 CDJ94864.1 - 3.2e-33 112.3 153.2 6.7e-05 23.1 1.2 18.5 19 0 0 19 19 19 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ94864.1 - 4.8e-26 89.2 154.2 0.0026 18.5 0.9 20.3 20 0 0 20 20 20 13 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDJ94864.1 - 4.9e-26 90.0 121.2 2.2e-07 31.0 0.3 20.0 21 0 0 21 21 21 12 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CDJ94864.1 - 1.7e-07 31.3 76.7 0.0029 17.9 0.0 15.4 17 0 0 17 17 15 5 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 CDJ94864.1 - 0.004 17.2 0.9 0.004 17.2 0.9 10.6 10 2 2 12 12 11 1 BED zinc finger zf-C2H2_6 PF13912.6 CDJ94864.1 - 0.012 15.6 7.4 0.019 14.9 1.7 16.5 17 1 0 17 17 17 0 C2H2-type zinc finger DUF4611 PF15387.6 CDJ94864.1 - 0.021 15.0 0.8 0.056 13.7 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) zf-met PF12874.7 CDJ94864.1 - 0.027 14.9 0.1 0.027 14.9 0.1 14.3 17 0 0 17 17 15 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 CDJ94864.1 - 0.072 12.9 0.1 0.072 12.9 0.1 11.9 13 0 0 13 13 11 0 zinc-finger C2H2-type TFIIF_alpha PF05793.12 CDJ94864.1 - 1.2 7.7 7.1 0.48 8.9 4.7 1.4 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP1_TM PF14812.6 CDJ94864.1 - 2.4 8.6 9.9 5.9 7.3 9.9 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 CDJ94864.1 - 4.5 7.7 10.9 13 6.3 10.9 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HTH_44 PF14641.6 CDJ94865.1 - 1.3e-18 67.5 3.0 3.9e-18 66.0 3.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 CDJ94865.1 - 1.1e-06 29.1 35.5 1.1e-06 29.1 35.5 5.2 1 1 3 4 4 4 1 Acidic N-terminal SPT6 Tex_N PF09371.10 CDJ94865.1 - 0.00019 21.2 1.2 0.00066 19.4 0.0 2.4 2 1 0 2 2 2 1 Tex-like protein N-terminal domain DUF3761 PF12587.8 CDJ94865.1 - 0.39 11.2 2.3 0.61 10.6 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3761) TPX2_importin PF12214.8 CDJ94865.1 - 7 6.8 13.7 6.2 7.0 0.3 2.5 2 0 0 2 2 2 0 Cell cycle regulated microtubule associated protein Malate_synthase PF01274.22 CDJ94866.1 - 0.012 14.0 0.3 0.012 13.9 0.3 1.1 1 0 0 1 1 1 0 Malate synthase Asp PF00026.23 CDJ94867.1 - 1.9e-83 280.5 3.0 2.3e-83 280.2 3.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ94867.1 - 2e-13 51.0 2.2 2e-12 47.7 2.2 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Kelch_1 PF01344.25 CDJ94868.1 - 1e-36 124.3 11.9 2.9e-07 30.0 0.1 6.6 6 1 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CDJ94868.1 - 9.4e-36 121.0 10.0 9.7e-08 32.0 0.1 6.3 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.15 CDJ94868.1 - 6.4e-34 114.6 11.0 8.9e-07 28.6 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 CDJ94868.1 - 1.5e-33 114.4 13.1 9.5e-09 35.3 0.0 7.5 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ94868.1 - 6.8e-33 112.1 11.2 8.2e-06 25.7 0.5 6.5 6 1 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 CDJ94868.1 - 3.7e-32 110.1 16.5 5.1e-07 29.6 0.0 6.7 6 2 0 6 6 6 5 Galactose oxidase, central domain CPBP PF02517.16 CDJ94869.1 - 1.7e-15 57.2 0.3 1.7e-15 57.2 0.3 2.2 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease DUF374 PF04028.13 CDJ94870.1 - 0.013 15.0 0.0 0.032 13.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF374) Patched PF02460.18 CDJ94871.1 - 1.1e-102 344.7 9.8 1.3e-102 344.4 9.8 1.0 1 0 0 1 1 1 1 Patched family Gsf2 PF11055.8 CDJ94871.1 - 0.066 12.0 1.0 0.11 11.3 1.0 1.2 1 0 0 1 1 1 0 Glucose signalling factor 2 SecD_SecF PF02355.16 CDJ94871.1 - 5.7 6.3 13.2 15 4.9 13.2 1.7 1 1 0 1 1 1 0 Protein export membrane protein ACR_tran PF00873.19 CDJ94871.1 - 6.9 4.2 15.2 13 3.2 14.4 1.6 1 1 1 2 2 2 0 AcrB/AcrD/AcrF family WD40 PF00400.32 CDJ94872.1 - 4.8e-19 68.4 8.0 0.0008 20.2 0.1 6.0 5 0 0 5 5 5 4 WD domain, G-beta repeat SARS_X4 PF08779.10 CDJ94872.1 - 0.036 14.3 0.0 0.093 12.9 0.0 1.6 1 0 0 1 1 1 0 SARS coronavirus X4 like ANAPC4_WD40 PF12894.7 CDJ94872.1 - 0.05 13.9 0.1 1.1 9.6 0.0 3.2 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 CDJ94872.1 - 0.065 13.3 0.0 12 6.0 0.0 3.4 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 CDJ94872.1 - 0.082 12.2 0.0 0.5 9.6 0.0 2.3 2 1 0 2 2 2 0 WD40-like domain CTNNB1_binding PF08347.11 CDJ94872.1 - 0.29 11.3 1.4 0.54 10.4 1.4 1.3 1 0 0 1 1 1 0 N-terminal CTNNB1 binding RVT_1 PF00078.27 CDJ94875.1 - 5.3e-39 134.0 0.0 9e-39 133.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_Tnp_Tc3_1 PF11427.8 CDJ94875.1 - 3.7e-07 29.9 0.0 9.3e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 Tc3 transposase HTH_38 PF13936.6 CDJ94875.1 - 0.00028 20.6 0.0 0.00076 19.2 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 CDJ94875.1 - 0.0012 18.5 0.0 0.0039 16.9 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain Gal-bind_lectin PF00337.22 CDJ94878.1 - 3.4e-40 136.7 0.1 1.1e-26 92.9 0.0 2.0 2 0 0 2 2 2 2 Galactoside-binding lectin RVT_1 PF00078.27 CDJ94879.1 - 1.7e-17 63.7 0.0 4.9e-17 62.2 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) START PF01852.19 CDJ94880.1 - 2.6e-40 138.1 0.1 3e-40 137.9 0.1 1.1 1 0 0 1 1 1 1 START domain MRP-S31 PF15433.6 CDJ94881.1 - 9.6e-62 209.5 2.0 1.5e-61 208.8 2.0 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 MamL-1 PF09596.10 CDJ94882.1 - 0.0014 18.9 4.4 0.0014 18.9 4.4 3.0 3 1 0 3 3 3 1 MamL-1 domain Endonuc_Holl PF10107.9 CDJ94882.1 - 6.6 6.6 7.9 0.37 10.6 1.4 1.9 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Y_phosphatase PF00102.27 CDJ94883.1 - 8.8e-77 257.8 0.0 1.3e-76 257.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PDZ PF00595.24 CDJ94883.1 - 1.4e-19 70.2 0.0 2.4e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDJ94883.1 - 3.4e-06 26.8 0.0 7.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Y_phosphatase3 PF13350.6 CDJ94883.1 - 0.0001 22.4 0.0 0.00016 21.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CDJ94883.1 - 0.0023 17.7 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PDZ_2 PF13180.6 CDJ94883.1 - 0.019 15.3 0.0 0.039 14.3 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PAP1 PF08601.10 CDJ94883.1 - 0.022 14.5 6.5 0.032 14.0 6.5 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 KA1 PF02149.19 CDJ94884.1 - 5.4e-07 29.3 0.2 8.4e-07 28.7 0.2 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 Amino_oxidase PF01593.24 CDJ94886.1 - 2.4e-19 69.9 0.1 3.7e-14 52.9 0.1 2.0 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase Glyco_transf_36 PF06165.11 CDJ94886.1 - 0.049 13.0 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 36 HTH_Tnp_Tc3_2 PF01498.18 CDJ94887.1 - 1.8e-25 88.9 0.5 3.4e-25 88.1 0.5 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 CDJ94887.1 - 0.0011 19.6 5.4 0.0022 18.6 0.5 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.6 CDJ94887.1 - 0.017 14.7 2.4 0.36 10.4 0.1 2.9 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 CDJ94887.1 - 0.062 12.8 0.3 3.8 7.1 0.0 2.8 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 CDJ94887.1 - 1.6 8.2 6.4 7.8 6.0 0.2 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 7TM_GPCR_Str PF10326.9 CDJ94889.1 - 1.2e-32 113.5 13.9 1.4e-32 113.2 13.9 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srj PF10319.9 CDJ94889.1 - 5.9e-25 88.3 7.7 7.9e-25 87.8 7.7 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Srh PF10318.9 CDJ94889.1 - 9.5e-07 28.1 9.3 1.3e-06 27.7 9.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7tm_1 PF00001.21 CDJ94889.1 - 0.0062 15.9 9.2 0.027 13.8 9.2 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) UPF0542 PF15086.6 CDJ94889.1 - 2.2 8.3 4.6 1.5 8.8 0.2 2.6 3 0 0 3 3 3 0 Uncharacterised protein family UPF0542 Collagen PF01391.18 CDJ94890.1 - 6.4e-27 93.1 101.6 1.5e-10 40.7 34.7 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ94890.1 - 3.5e-15 55.8 0.3 4.4e-15 55.5 0.3 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain COX14 PF14880.6 CDJ94890.1 - 0.00048 19.9 1.5 0.00069 19.4 1.5 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c assembly FSA_C PF10479.9 CDJ94891.1 - 5.5e-46 157.0 6.0 1.2e-33 116.3 0.1 3.9 2 2 1 3 3 3 3 Fragile site-associated protein C-terminus zf-RING_9 PF13901.6 CDJ94892.1 - 7.9e-46 156.6 9.6 1.5e-45 155.7 9.6 1.4 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon TPR_1 PF00515.28 CDJ94893.1 - 2.1e-10 40.0 4.1 2.1e-05 24.1 0.3 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ94893.1 - 4.2e-10 39.0 3.8 2.6e-05 24.0 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ94893.1 - 6.2e-08 33.0 2.8 0.00034 21.1 0.8 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ94893.1 - 6.2e-08 32.3 10.0 0.00039 20.4 0.2 4.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ94893.1 - 8e-08 32.5 1.6 0.094 13.0 0.2 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ94893.1 - 1.4e-07 31.1 0.3 1.9e-06 27.4 0.1 2.4 2 0 0 2 2 2 1 TPR repeat TPR_15 PF13429.6 CDJ94893.1 - 3.6e-07 29.7 1.7 1e-06 28.2 1.8 1.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ94893.1 - 1.8e-06 28.3 0.3 0.0077 17.0 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ94893.1 - 2.4e-06 27.6 0.3 0.00022 21.3 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.12 CDJ94893.1 - 4.4e-06 26.6 3.2 0.052 13.6 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ94893.1 - 1.1e-05 25.5 1.4 7.4 7.2 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ94893.1 - 9.7e-05 22.1 2.1 0.064 13.3 0.1 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ94893.1 - 0.00029 21.0 6.1 0.11 12.8 0.3 2.4 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CDJ94893.1 - 0.00032 21.1 3.3 0.19 12.4 0.1 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ94893.1 - 0.0005 20.7 0.2 0.059 14.0 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ94893.1 - 0.032 14.1 1.8 9.2 6.3 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ94893.1 - 0.086 12.9 4.4 7.4 6.7 0.1 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 CDJ94893.1 - 0.3 11.2 3.5 0.94 9.6 0.1 2.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain NARP1 PF12569.8 CDJ94894.1 - 3e-115 386.1 0.1 3.6e-115 385.8 0.1 1.0 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 CDJ94894.1 - 3e-10 39.4 9.6 0.00015 21.6 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ94894.1 - 1.3e-08 34.9 9.1 0.0097 16.7 0.0 5.7 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ94894.1 - 3.1e-08 33.2 4.4 0.00017 21.5 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ94894.1 - 6.7e-08 32.0 1.9 0.001 18.8 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ94894.1 - 1.7e-06 28.6 4.8 0.014 16.0 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ94894.1 - 3.3e-06 27.5 8.8 0.0072 16.8 0.9 4.0 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ94894.1 - 7.2e-05 22.5 8.4 0.066 13.3 0.0 5.7 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ94894.1 - 0.00012 22.3 11.6 0.3 11.4 0.0 5.3 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CDJ94894.1 - 0.00056 19.4 0.4 0.016 14.6 0.4 2.2 2 0 0 2 2 2 1 MalT-like TPR region TPR_21 PF09976.9 CDJ94894.1 - 0.0006 19.6 0.4 0.012 15.4 0.0 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat-like domain PPR PF01535.20 CDJ94894.1 - 0.0027 17.8 5.3 3.6 8.0 0.1 4.5 4 1 1 5 5 5 1 PPR repeat ANAPC3 PF12895.7 CDJ94894.1 - 0.0036 17.5 8.0 0.08 13.2 1.3 4.0 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 CDJ94894.1 - 0.0037 16.5 0.5 0.67 9.1 0.2 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ94894.1 - 0.015 14.9 4.8 0.034 13.8 0.0 3.4 4 0 0 4 4 4 0 TPR repeat PPR_1 PF12854.7 CDJ94894.1 - 0.016 14.9 2.0 7.9 6.3 0.1 3.8 4 0 0 4 4 4 0 PPR repeat TPR_4 PF07721.14 CDJ94894.1 - 0.018 15.6 1.2 43 5.2 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ94894.1 - 0.04 14.6 8.7 0.51 11.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ94894.1 - 0.6 10.1 10.1 4.3 7.3 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat NARP1 PF12569.8 CDJ94895.1 - 5.2e-19 68.5 4.0 6.5e-19 68.2 4.0 1.1 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 PRP3 PF08572.10 CDJ94895.1 - 0.0015 18.3 0.8 0.002 17.9 0.8 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF4355 PF14265.6 CDJ94895.1 - 0.012 15.9 5.7 0.018 15.3 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DNA_ligase_A_C PF04679.15 CDJ94895.1 - 0.062 13.9 0.2 0.18 12.4 0.2 1.8 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region DUF3824 PF12868.7 CDJ94895.1 - 0.096 13.3 0.9 0.14 12.8 0.9 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) GHMP_kinases_C PF08544.13 CDJ94897.1 - 3.9e-07 30.4 0.0 8.2e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal MMS1_N PF10433.9 CDJ94898.1 - 0.13 10.8 0.0 0.13 10.8 0.0 1.0 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ly-6_related PF06579.12 CDJ94900.1 - 5.2e-31 107.5 1.0 6.2e-31 107.3 1.0 1.1 1 0 0 1 1 1 1 Caenorhabditis elegans ly-6-related protein QVR PF17064.5 CDJ94900.1 - 0.038 14.2 5.2 2.6 8.3 5.2 2.7 1 1 0 1 1 1 0 Sleepless protein UPAR_LY6 PF00021.21 CDJ94900.1 - 0.75 10.5 6.9 0.1 13.3 1.3 2.4 2 1 0 2 2 2 0 u-PAR/Ly-6 domain Ank_2 PF12796.7 CDJ94901.1 - 1.9e-27 95.7 3.5 4.2e-15 56.1 0.2 2.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ94901.1 - 1.7e-18 66.7 0.3 8.7e-11 42.1 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_1 PF00018.28 CDJ94901.1 - 3.8e-14 52.0 0.3 7.6e-14 51.0 0.3 1.6 1 0 0 1 1 1 1 SH3 domain Ank_3 PF13606.6 CDJ94901.1 - 5.9e-14 50.8 0.3 1.6e-05 24.9 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 CDJ94901.1 - 2.9e-13 49.6 0.3 9.7e-06 25.8 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CDJ94901.1 - 6.7e-13 48.6 0.8 5.6e-09 36.1 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_2 PF07653.17 CDJ94901.1 - 2.4e-10 39.9 0.0 4.9e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CDJ94901.1 - 3.2e-10 39.7 0.3 6.6e-10 38.7 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF641 PF04859.12 CDJ94901.1 - 0.028 14.8 4.6 0.11 12.8 4.3 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF3135 PF11333.8 CDJ94901.1 - 0.12 12.6 1.2 0.31 11.3 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) ATG16 PF08614.11 CDJ94901.1 - 0.89 9.7 27.5 0.14 12.3 18.8 2.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF4404 PF14357.6 CDJ94901.1 - 1.4 9.6 6.2 0.6 10.8 1.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) FUSC PF04632.12 CDJ94901.1 - 2.6 6.5 9.5 4.9 5.6 9.5 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family Mod_r PF07200.13 CDJ94901.1 - 4.6 7.4 13.4 0.43 10.7 8.1 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Neur_chan_LBD PF02931.23 CDJ94902.1 - 1.8e-27 96.2 0.0 2.7e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ94902.1 - 8.3e-15 55.5 2.0 8.3e-15 55.5 2.0 2.4 2 1 0 3 3 3 1 Neurotransmitter-gated ion-channel transmembrane region gpD PF02925.16 CDJ94902.1 - 0.11 12.5 0.1 0.32 10.9 0.1 1.8 2 0 0 2 2 2 0 Bacteriophage scaffolding protein D PAZ PF02170.22 CDJ94903.1 - 4.2e-07 29.9 0.0 7.6e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Piwi PF02171.17 CDJ94904.1 - 9.2e-73 245.1 0.0 1.2e-72 244.7 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoL2 PF16488.5 CDJ94904.1 - 6.3e-10 39.2 0.0 2.4e-09 37.4 0.0 2.1 1 0 0 1 1 1 1 Argonaute linker 2 domain HGTP_anticodon PF03129.20 CDJ94904.1 - 0.0059 16.7 0.2 0.12 12.6 0.1 2.6 3 0 0 3 3 3 1 Anticodon binding domain AF-4 PF05110.13 CDJ94904.1 - 0.086 10.9 0.0 0.13 10.3 0.0 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein AhpC-TSA PF00578.21 CDJ94904.1 - 0.18 11.8 0.0 8.7 6.3 0.0 2.3 2 0 0 2 2 2 0 AhpC/TSA family RRM_1 PF00076.22 CDJ94905.1 - 2e-34 117.2 0.0 2.3e-17 62.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ94905.1 - 9e-05 22.5 0.0 0.29 11.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif Cas_Cas2CT1978 PF09707.10 CDJ94905.1 - 0.2 11.7 0.0 0.66 10.1 0.0 1.8 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) RRM_1 PF00076.22 CDJ94906.1 - 8.6e-09 35.1 0.1 1.2e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bac_small_YrzI PF09501.10 CDJ94906.1 - 0.067 13.3 0.0 3.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) DcpS_C PF11969.8 CDJ94907.1 - 4.5e-25 88.3 0.4 4.9e-25 88.2 0.4 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 CDJ94907.1 - 5.2e-11 43.2 0.2 8.5e-11 42.5 0.2 1.2 1 0 0 1 1 1 1 HIT domain SDA1 PF05285.12 CDJ94908.1 - 1.3e-67 228.7 31.4 1.3e-67 228.7 31.4 2.1 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 CDJ94908.1 - 4e-15 55.9 0.1 1.9e-14 53.7 0.0 2.2 2 0 0 2 2 2 1 NUC130/3NT domain DUF4070 PF13282.6 CDJ94908.1 - 0.0081 16.3 1.0 4.5 7.4 0.3 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4070) UNC45-central PF11701.8 CDJ94908.1 - 0.065 13.2 0.9 1.2 9.1 0.1 3.1 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central DUF913 PF06025.12 CDJ94908.1 - 6.5 5.6 7.7 9.6 5.1 0.2 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) CCDC144C PF14915.6 CDJ94909.1 - 0.00013 21.2 1.7 0.00016 20.9 1.7 1.4 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region KLRAQ PF10205.9 CDJ94909.1 - 0.00014 22.1 1.5 0.00014 22.1 1.5 1.7 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein GAS PF13851.6 CDJ94909.1 - 0.00045 19.6 5.2 0.00045 19.6 5.2 1.4 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding MAD PF05557.13 CDJ94909.1 - 0.0036 15.7 6.8 0.0041 15.6 6.8 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Fez1 PF06818.15 CDJ94909.1 - 0.0043 17.5 8.4 0.0053 17.2 8.4 1.1 1 0 0 1 1 1 1 Fez1 Filament PF00038.21 CDJ94909.1 - 0.0054 16.4 4.0 0.0063 16.1 4.0 1.1 1 0 0 1 1 1 1 Intermediate filament protein Snapin_Pallidin PF14712.6 CDJ94909.1 - 0.018 15.5 1.5 0.03 14.7 1.5 1.4 1 0 0 1 1 1 0 Snapin/Pallidin HIP1_clath_bdg PF16515.5 CDJ94909.1 - 0.019 15.6 6.0 0.031 14.9 6.0 1.4 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4201 PF13870.6 CDJ94909.1 - 0.023 14.4 3.7 0.023 14.4 3.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) APG6_N PF17675.1 CDJ94909.1 - 0.026 15.0 10.4 0.031 14.8 10.3 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4349 PF14257.6 CDJ94909.1 - 0.029 13.8 0.5 0.035 13.5 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Spc7 PF08317.11 CDJ94909.1 - 0.03 13.2 5.8 0.036 12.9 5.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FAS_I_H PF18314.1 CDJ94909.1 - 0.055 13.1 1.5 0.067 12.8 0.9 1.4 1 1 0 1 1 1 0 Fatty acid synthase type I helical domain TMPIT PF07851.13 CDJ94909.1 - 0.24 10.6 2.8 0.26 10.5 2.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein UPF0242 PF06785.11 CDJ94909.1 - 0.27 11.3 5.9 0.32 11.1 5.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ly49 PF08391.10 CDJ94909.1 - 0.52 10.7 3.7 0.49 10.8 2.8 1.4 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region DUF4407 PF14362.6 CDJ94909.1 - 0.55 9.5 3.2 0.57 9.5 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 CDJ94909.1 - 0.67 10.2 5.2 0.86 9.9 4.6 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 ADIP PF11559.8 CDJ94909.1 - 1 9.4 10.7 1.6 8.8 10.7 1.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding MCU PF04678.13 CDJ94909.1 - 1.3 9.1 3.9 1.8 8.6 3.9 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter EF-hand_7 PF13499.6 CDJ94910.1 - 1.9e-06 28.2 4.0 0.00096 19.6 0.4 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ94910.1 - 2e-06 27.3 3.9 0.00048 19.8 1.5 4.0 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 CDJ94910.1 - 2.1e-06 26.9 6.2 0.00099 18.5 2.1 3.7 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 CDJ94910.1 - 0.00018 21.3 1.7 0.33 10.8 0.7 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ94910.1 - 0.00054 19.3 4.7 0.0081 15.6 1.8 3.1 3 0 0 3 3 3 1 EF hand CAP PF00188.26 CDJ94911.1 - 0.031 15.1 0.0 0.86 10.5 0.0 2.2 1 1 0 1 1 1 0 Cysteine-rich secretory protein family DUF3717 PF12512.8 CDJ94911.1 - 0.038 13.9 0.0 0.093 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3717) Ins_beta PF03488.14 CDJ94912.1 - 7.4e-08 32.3 4.5 0.0012 18.8 2.2 2.2 2 0 0 2 2 2 2 Nematode insulin-related peptide beta type Insulin PF00049.18 CDJ94912.1 - 1.3e-05 26.1 6.9 0.026 15.5 3.2 2.1 1 1 1 2 2 2 2 Insulin/IGF/Relaxin family Ank_2 PF12796.7 CDJ94913.1 - 1e-22 80.5 3.8 2.9e-10 40.6 0.8 3.1 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ94913.1 - 6.3e-19 67.8 5.2 2.2e-06 27.8 0.5 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CDJ94913.1 - 2.6e-14 52.9 6.4 4.4e-05 23.7 0.1 6.1 5 1 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 CDJ94913.1 - 6.9e-13 47.5 2.5 0.024 15.1 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 CDJ94913.1 - 1.3e-12 47.9 2.8 0.0005 20.6 0.0 5.3 2 2 3 5 5 5 4 Ankyrin repeats (many copies) FERM_f0 PF16511.5 CDJ94913.1 - 0.0034 17.7 0.0 0.0075 16.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM Peptidase_M50 PF02163.22 CDJ94915.1 - 5.4e-21 75.0 0.0 8.9e-21 74.3 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M50 PDZ_2 PF13180.6 CDJ94915.1 - 0.0057 17.0 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain VEFS-Box PF09733.9 CDJ94915.1 - 0.077 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 VEFS-Box of polycomb protein MerC PF03203.14 CDJ94915.1 - 0.95 9.9 7.0 0.61 10.5 0.6 2.7 2 1 0 2 2 2 0 MerC mercury resistance protein TLD PF07534.16 CDJ94916.1 - 2.5e-05 24.5 0.2 0.00015 22.0 0.0 2.0 1 1 1 2 2 2 1 TLD zf-H2C2_5 PF13909.6 CDJ94917.1 - 0.0021 17.7 0.3 0.0021 17.7 0.3 3.0 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_9 PF16293.5 CDJ94917.1 - 0.024 14.5 1.5 3.1 7.7 0.1 3.4 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2 PF00096.26 CDJ94917.1 - 0.2 12.2 25.6 0.36 11.4 0.5 5.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 CDJ94917.1 - 1.1 9.9 5.5 21 5.8 0.0 3.7 3 0 0 3 3 3 0 FOXP coiled-coil domain DUF3557 PF12078.8 CDJ94918.1 - 0.0013 18.7 0.2 0.0021 18.1 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3557) zf-PARP PF00645.18 CDJ94918.1 - 0.084 13.7 0.3 0.28 12.1 0.1 1.9 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region JmjC PF02373.22 CDJ94919.1 - 4.7e-21 75.4 3.1 2.3e-20 73.1 3.1 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CDJ94919.1 - 1.8e-13 50.8 6.1 4.2e-11 43.0 6.1 2.8 1 1 0 1 1 1 1 Cupin-like domain Methyltransf_16 PF10294.9 CDJ94920.1 - 2.2e-30 105.7 0.0 2.9e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 CDJ94920.1 - 4.3e-05 23.1 0.0 5e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CDJ94920.1 - 0.00013 22.6 0.0 0.00022 21.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ94920.1 - 0.00065 19.3 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 CDJ94920.1 - 0.0022 17.8 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MOR2-PAG1_mid PF14228.6 CDJ94920.1 - 0.082 10.5 0.0 0.11 10.1 0.0 1.1 1 0 0 1 1 1 0 Cell morphogenesis central region Methyltransf_23 PF13489.6 CDJ94920.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 CDJ94920.1 - 0.19 11.5 0.0 0.24 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.19 CDJ94920.1 - 0.2 11.4 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) COMM_domain PF07258.14 CDJ94921.1 - 3e-05 24.0 0.0 8.1e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 COMM domain Beta-Casp PF10996.8 CDJ94921.1 - 0.15 12.3 0.0 0.21 11.9 0.0 1.3 1 1 0 1 1 1 0 Beta-Casp domain Sigma70_ner PF04546.13 CDJ94922.1 - 0.055 13.3 2.6 0.066 13.1 2.6 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Pkinase PF00069.25 CDJ94923.1 - 0.15 11.4 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain XPG_I PF00867.18 CDJ94924.1 - 1.3e-17 63.9 0.0 3.7e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CDJ94924.1 - 4.8e-16 59.1 0.0 1.1e-15 58.0 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 CDJ94924.1 - 9.4e-05 22.0 0.0 0.0002 20.9 0.0 1.6 1 0 0 1 1 1 1 XPG domain containing MAS20 PF02064.15 CDJ94924.1 - 0.23 11.6 0.8 0.97 9.5 0.0 2.4 2 0 0 2 2 2 0 MAS20 protein import receptor DUF1758 PF05585.12 CDJ94925.1 - 1.4e-08 34.6 0.0 3.3e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 CDJ94925.1 - 0.0018 18.9 0.1 0.0032 18.1 0.1 1.5 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ94925.1 - 0.11 13.1 0.0 0.65 10.6 0.0 2.0 1 1 1 2 2 2 0 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.8 CDJ94925.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Ty3 transposon peptidase dCMP_cyt_deam_1 PF00383.23 CDJ94928.1 - 2.3e-09 37.0 0.7 3.4e-09 36.5 0.7 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CDJ94928.1 - 0.00093 19.0 0.1 0.0016 18.2 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase NHL PF01436.21 CDJ94929.1 - 7.1e-21 73.1 16.7 1.5e-06 28.0 0.3 5.2 5 0 0 5 5 5 4 NHL repeat zf-B_box PF00643.24 CDJ94929.1 - 6.2e-10 39.1 19.4 1.8e-06 28.0 3.4 4.2 4 1 0 4 4 3 2 B-box zinc finger zf-RING_UBOX PF13445.6 CDJ94929.1 - 1.5e-05 24.9 3.2 1.5e-05 24.9 3.2 3.8 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDJ94929.1 - 0.00098 19.0 3.5 0.00098 19.0 3.5 4.2 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ94929.1 - 0.0015 18.6 1.2 0.0015 18.6 1.2 4.0 4 0 0 4 4 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CDJ94929.1 - 0.0045 16.8 2.9 0.0045 16.8 2.9 4.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ94929.1 - 0.0079 16.1 9.8 0.0079 16.1 9.8 4.4 2 2 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CDJ94929.1 - 0.0088 15.9 4.3 0.0088 15.9 4.3 4.8 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) DUF5128 PF17170.4 CDJ94929.1 - 0.0097 15.1 0.1 0.022 13.9 0.0 1.6 2 0 0 2 2 2 1 6-bladed beta-propeller DUF4934 PF16288.5 CDJ94929.1 - 0.031 14.2 0.0 0.15 12.0 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4934) SGL PF08450.12 CDJ94929.1 - 0.15 11.6 0.0 8.6 5.9 0.0 3.1 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region Siva PF05458.12 CDJ94929.1 - 0.81 9.3 11.5 1.1 8.9 3.8 2.6 2 0 0 2 2 2 0 Cd27 binding protein (Siva) ORC4_C PF14629.6 CDJ94930.1 - 5.5e-06 25.9 0.6 9.4e-06 25.1 0.6 1.5 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA PF00004.29 CDJ94930.1 - 8.6e-06 26.2 0.1 1.6e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ94930.1 - 0.0092 16.4 3.1 0.94 9.8 3.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 CDJ94930.1 - 0.0095 15.1 0.1 0.015 14.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ATPase_2 PF01637.18 CDJ94930.1 - 0.059 13.3 0.2 0.82 9.5 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea ATP-synt_ab PF00006.25 CDJ94930.1 - 0.082 12.6 0.2 0.25 11.0 0.0 1.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Smr PF01713.21 CDJ94930.1 - 0.1 13.0 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 Smr domain Peptidase_A17 PF05380.13 CDJ94931.1 - 6.6e-36 123.8 0.1 1.7e-35 122.5 0.1 1.7 1 0 0 1 1 1 1 Pao retrotransposon peptidase DUF1759 PF03564.15 CDJ94931.1 - 1.2e-27 96.6 2.9 3.7e-27 95.1 2.9 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 CDJ94931.1 - 8.1e-19 68.0 0.0 1.8e-17 63.6 0.0 2.6 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Integrase_H2C2 PF17921.1 CDJ94931.1 - 4e-11 42.9 0.6 1.8e-10 40.8 0.2 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CDJ94931.1 - 0.0036 17.5 0.2 0.0098 16.1 0.2 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 CDJ94931.1 - 0.017 15.8 0.0 0.042 14.5 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease DUF4407 PF14362.6 CDJ94932.1 - 5.6 6.2 10.0 1.4 8.2 5.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SNF PF00209.18 CDJ94933.1 - 4.6e-16 58.6 10.6 6.4e-16 58.1 10.6 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family FPL PF09758.9 CDJ94934.1 - 5e-59 198.6 9.1 9.8e-59 197.6 9.1 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein Herpes_heli_pri PF05774.11 CDJ94934.1 - 0.19 11.9 0.9 6.5 7.0 0.1 3.0 3 0 0 3 3 3 0 Herpesvirus helicase-primase complex component ATP_bind_1 PF03029.17 CDJ94935.1 - 8.3e-82 274.6 0.0 1.1e-81 274.3 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 CDJ94935.1 - 2.5e-09 37.0 0.0 2.5e-08 33.7 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CDJ94935.1 - 2.1e-06 27.3 0.0 0.015 14.7 0.0 2.2 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 CDJ94935.1 - 1e-05 25.1 0.0 0.0002 20.9 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 CDJ94935.1 - 3.1e-05 24.0 0.0 0.00023 21.2 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CDJ94935.1 - 5.9e-05 23.5 0.0 0.00015 22.2 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain Ras PF00071.22 CDJ94935.1 - 0.00056 19.5 0.0 0.18 11.4 0.0 2.3 2 1 0 2 2 2 1 Ras family cobW PF02492.19 CDJ94935.1 - 0.00099 18.7 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CLP1_P PF16575.5 CDJ94935.1 - 0.0011 18.8 0.0 0.069 12.9 0.0 2.3 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_24 PF13479.6 CDJ94935.1 - 0.0016 18.2 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CDJ94935.1 - 0.0031 17.2 0.0 0.02 14.5 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 CDJ94935.1 - 0.0044 16.9 0.0 0.062 13.2 0.0 2.2 1 1 0 1 1 1 1 NTPase Arf PF00025.21 CDJ94935.1 - 0.0055 16.2 0.0 2.8 7.3 0.0 2.8 2 1 1 3 3 3 1 ADP-ribosylation factor family DUF87 PF01935.17 CDJ94935.1 - 0.0063 16.6 0.0 0.1 12.7 0.0 2.1 2 0 0 2 2 2 1 Helicase HerA, central domain NACHT PF05729.12 CDJ94935.1 - 0.0066 16.4 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 CDJ94935.1 - 0.0092 16.3 0.0 0.038 14.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 CDJ94935.1 - 0.011 14.8 0.0 0.82 8.6 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FtsK_SpoIIIE PF01580.18 CDJ94935.1 - 0.014 14.8 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_5 PF07728.14 CDJ94935.1 - 0.015 15.3 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CDJ94935.1 - 0.018 15.2 0.0 0.034 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 CDJ94935.1 - 0.021 14.9 0.3 4.7 7.2 0.0 2.7 3 0 0 3 3 3 0 Dynamin family PduV-EutP PF10662.9 CDJ94935.1 - 0.022 14.5 0.0 0.67 9.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 CDJ94935.1 - 0.026 13.9 0.0 0.23 10.8 0.0 2.1 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Roc PF08477.13 CDJ94935.1 - 0.038 14.2 0.0 0.57 10.4 0.0 2.5 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 CDJ94935.1 - 0.041 13.4 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region KAP_NTPase PF07693.14 CDJ94935.1 - 0.043 13.0 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_18 PF13238.6 CDJ94935.1 - 0.071 13.7 0.0 0.27 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 CDJ94935.1 - 0.083 12.0 0.3 1 8.5 0.0 2.6 3 1 0 3 3 3 0 G-protein alpha subunit CbiA PF01656.23 CDJ94935.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Bac_surface_Ag PF01103.23 CDJ94936.1 - 6e-30 104.8 0.0 1.5e-29 103.6 0.0 1.4 1 1 0 1 1 1 1 Surface antigen Ham1p_like PF01725.16 CDJ94937.1 - 4.7e-56 189.7 0.0 5.3e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family RPEL PF02755.15 CDJ94937.1 - 0.079 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 RPEL repeat IPPT PF01715.17 CDJ94938.1 - 7.9e-63 212.3 0.1 1.7e-62 211.2 0.1 1.5 2 0 0 2 2 2 1 IPP transferase IPT PF01745.16 CDJ94938.1 - 0.00025 20.5 0.0 0.00053 19.5 0.0 1.5 1 0 0 1 1 1 1 Isopentenyl transferase zf-met PF12874.7 CDJ94938.1 - 0.00034 20.9 0.1 0.00062 20.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_18 PF13238.6 CDJ94938.1 - 0.0011 19.5 4.4 0.9 10.1 4.4 2.6 1 1 0 1 1 1 1 AAA domain zf-C2H2_jaz PF12171.8 CDJ94938.1 - 0.0018 18.5 0.0 0.0033 17.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_33 PF13671.6 CDJ94938.1 - 0.0091 16.2 0.0 0.066 13.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 CDJ94938.1 - 0.028 14.1 0.2 0.95 9.2 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase Hydin_ADK PF17213.3 CDJ94938.1 - 0.084 13.1 0.5 0.31 11.3 0.1 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain zf-U1 PF06220.12 CDJ94938.1 - 0.11 12.3 0.1 0.36 10.6 0.1 1.8 1 0 0 1 1 1 0 U1 zinc finger SKI PF01202.22 CDJ94938.1 - 0.12 12.4 1.4 4.8 7.3 0.1 3.1 3 0 0 3 3 3 0 Shikimate kinase Ploopntkinase3 PF18751.1 CDJ94938.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 EF1_GNE PF00736.19 CDJ94939.1 - 7.2e-35 119.0 1.3 7.2e-35 119.0 1.3 1.6 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 CDJ94939.1 - 1.8e-10 41.1 4.0 1.8e-10 41.1 4.0 2.5 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 CDJ94939.1 - 0.039 14.1 0.2 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Aconitase PF00330.20 CDJ94941.1 - 1.3e-76 258.4 0.1 2.3e-70 237.9 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CDJ94941.1 - 1.4e-45 154.8 0.1 3.1e-45 153.7 0.0 1.6 2 0 0 2 2 2 1 Aconitase C-terminal domain Hydrolase PF00702.26 CDJ94942.1 - 1.7e-47 162.4 0.8 3.2e-47 161.5 0.2 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CDJ94942.1 - 7.4e-45 152.7 4.4 7.4e-45 152.7 4.4 3.9 4 0 0 4 4 4 1 E1-E2 ATPase HMA PF00403.26 CDJ94942.1 - 9.7e-45 150.9 10.0 3.3e-15 56.3 0.1 4.7 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase_3 PF08282.12 CDJ94942.1 - 0.028 14.2 0.3 0.11 12.2 0.2 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF3671 PF12420.8 CDJ94942.1 - 0.11 12.5 0.8 6.7 6.8 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function DUF2200 PF09966.9 CDJ94942.1 - 0.2 11.8 2.3 13 6.0 0.0 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2200) GST_N_3 PF13417.6 CDJ94943.1 - 7.3e-19 68.0 0.0 1.8e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CDJ94943.1 - 2.8e-14 53.2 0.0 5e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDJ94943.1 - 3.4e-13 49.7 0.1 4.7e-12 46.0 0.1 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CDJ94943.1 - 2.7e-07 30.7 0.0 6e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDJ94943.1 - 1.1e-06 28.6 0.1 5.3e-06 26.4 0.3 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDJ94943.1 - 0.0081 16.3 0.0 0.018 15.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 CDJ94943.1 - 0.013 15.7 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin DUF4728 PF15860.5 CDJ94944.1 - 0.0038 17.9 15.5 0.0038 17.9 15.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4728) DUF2085 PF09858.9 CDJ94944.1 - 0.027 14.9 7.1 0.027 14.9 7.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) ACBP PF00887.19 CDJ94945.1 - 3.9e-21 75.1 0.1 8.3e-21 74.0 0.1 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Annexin PF00191.20 CDJ94946.1 - 2.2e-97 319.1 6.3 1.3e-25 89.2 0.0 4.0 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.6 CDJ94946.1 - 0.031 14.7 0.2 7.6 7.1 0.0 3.3 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Phlebovirus_G2 PF07245.11 CDJ94947.1 - 6.6e-20 71.1 22.7 1.7e-17 63.1 8.2 2.7 3 0 0 3 3 3 2 Phlebovirus glycoprotein G2 DUF5641 PF18701.1 CDJ94947.1 - 2.6e-17 62.8 0.5 7.1e-17 61.4 0.5 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5641) Integrase_H2C2 PF17921.1 CDJ94947.1 - 1.7e-14 53.6 1.0 5.8e-14 52.0 1.0 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDJ94947.1 - 6.9e-13 48.8 0.1 2.1e-12 47.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 CDJ94947.1 - 3.9e-06 27.0 2.3 3.9e-06 27.0 2.3 2.2 2 0 0 2 2 2 1 H2C2 zinc finger rve_3 PF13683.6 CDJ94947.1 - 0.0002 21.1 0.1 0.005 16.6 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain DUF4910 PF16254.5 CDJ94947.1 - 0.032 13.1 0.4 0.056 12.3 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4910) Peptidase_A17 PF05380.13 CDJ94948.1 - 5.5e-27 94.8 0.1 1.1e-26 93.7 0.1 1.5 1 0 0 1 1 1 1 Pao retrotransposon peptidase RVT_1 PF00078.27 CDJ94948.1 - 2e-07 30.8 0.1 3.6e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1758 PF05585.12 CDJ94948.1 - 0.0016 18.2 0.0 0.0057 16.4 0.0 2.0 2 0 0 2 2 2 1 Putative peptidase (DUF1758) PhoR PF11808.8 CDJ94948.1 - 0.0067 16.8 0.4 0.015 15.6 0.0 1.8 2 0 0 2 2 2 1 Phosphate regulon sensor protein PhoR DUF929 PF06053.11 CDJ94949.1 - 0.0099 15.2 0.0 0.011 15.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF929) Ank_2 PF12796.7 CDJ94951.1 - 1.1e-34 118.9 0.5 8.5e-19 67.9 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ94951.1 - 2.1e-30 104.7 0.7 2.8e-12 46.9 0.0 4.8 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 CDJ94951.1 - 2.1e-27 94.3 3.0 1.7e-05 25.1 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 CDJ94951.1 - 5.4e-26 90.3 4.9 2.4e-10 40.4 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) PRKG1_interact PF15898.5 CDJ94951.1 - 6.1e-26 91.3 3.0 6.1e-26 91.3 3.0 3.7 3 0 0 3 3 3 1 cGMP-dependent protein kinase interacting domain Ank_3 PF13606.6 CDJ94951.1 - 1.7e-25 86.3 0.6 9e-05 22.6 0.1 5.6 5 0 0 5 5 5 5 Ankyrin repeat DNase_II PF03265.15 CDJ94952.1 - 7.1e-55 186.6 0.6 8.2e-55 186.3 0.6 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II DNase_II PF03265.15 CDJ94953.1 - 1.2e-92 310.7 0.7 1.3e-92 310.6 0.7 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II DNase_II PF03265.15 CDJ94954.1 - 1.7e-77 260.9 0.6 2.1e-77 260.6 0.6 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II SelP_N PF04592.14 CDJ94956.1 - 1.9 7.8 7.1 2.9 7.2 7.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF5090 PF17009.5 CDJ94956.1 - 9.9 6.1 8.7 17 5.3 8.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) ET PF01684.16 CDJ94957.1 - 0.028 14.7 0.7 0.046 14.1 0.7 1.4 1 0 0 1 1 1 0 ET module EF-hand_1 PF00036.32 CDJ94958.1 - 8.2e-15 53.2 8.6 2.3e-07 29.9 3.3 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CDJ94958.1 - 2.2e-11 42.7 5.7 1.6e-06 27.6 2.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDJ94958.1 - 8.3e-11 40.9 6.9 1e-05 24.8 1.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDJ94958.1 - 1.2e-09 38.4 4.2 1.2e-09 38.4 4.2 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CDJ94958.1 - 8e-08 32.0 8.5 3.2e-07 30.1 2.1 2.6 1 1 2 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ94958.1 - 8.3e-05 22.9 0.7 8.3e-05 22.9 0.7 2.2 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CDJ94958.1 - 0.022 14.7 1.4 1.2 9.0 0.7 2.3 1 1 1 2 2 2 0 Caleosin related protein DUF4140 PF13600.6 CDJ94958.1 - 0.19 12.2 2.0 0.24 11.9 0.5 1.8 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) GTP_EFTU PF00009.27 CDJ94959.1 - 1.3e-31 109.6 0.0 1.3e-31 109.6 0.0 4.8 3 2 1 4 4 4 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CDJ94959.1 - 1.2e-19 70.3 0.2 3.9e-19 68.7 0.2 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 CDJ94959.1 - 4.3e-09 36.6 0.2 3.5e-08 33.7 0.2 2.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDJ94959.1 - 5e-06 26.6 2.5 6.7e-06 26.2 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CDJ94959.1 - 0.0004 20.2 0.0 0.0004 20.2 0.0 2.8 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein MFS_1 PF07690.16 CDJ94960.1 - 2.6e-10 39.7 1.4 2.6e-10 39.7 1.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ94960.1 - 6.6e-07 28.5 2.1 9.4e-07 28.0 2.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 CDJ94960.1 - 3.2e-05 22.7 0.6 4.1e-05 22.3 0.6 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein G-patch PF01585.23 CDJ94961.1 - 1.5e-16 60.0 2.6 2.8e-16 59.1 2.6 1.5 1 0 0 1 1 1 1 G-patch domain OCRE PF17780.1 CDJ94961.1 - 2.5e-11 43.4 11.3 2.5e-11 43.4 11.3 2.1 3 0 0 3 3 3 1 OCRE domain FHA PF00498.26 CDJ94961.1 - 4.8e-11 42.8 0.1 1.1e-10 41.7 0.1 1.6 1 0 0 1 1 1 1 FHA domain G-patch_2 PF12656.7 CDJ94961.1 - 2.6e-08 33.8 3.2 2.9e-08 33.7 1.6 1.9 2 0 0 2 2 2 1 G-patch domain Yop-YscD_cpl PF16697.5 CDJ94961.1 - 2.5e-05 24.5 0.1 5.8e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DDE_Tnp_1_4 PF13701.6 CDJ94961.1 - 0.052 11.8 0.0 0.077 11.3 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain group 1 Peptidase_M20 PF01546.28 CDJ94962.1 - 4e-30 105.1 0.0 5e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CDJ94962.1 - 6.8e-13 48.5 0.0 1.1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Guanylate_cyc PF00211.20 CDJ94963.1 - 4e-62 209.1 0.1 1.1e-60 204.4 0.0 2.6 3 0 0 3 3 3 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 CDJ94963.1 - 4.5e-49 167.4 1.1 7.6e-49 166.7 1.1 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 CDJ94963.1 - 2.8e-23 82.5 0.0 2.1e-22 79.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ94963.1 - 1.2e-20 74.0 0.0 3.1e-20 72.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 CDJ94963.1 - 0.0025 17.3 0.7 0.0046 16.4 0.7 1.4 1 0 0 1 1 1 1 Heme NO binding associated Peripla_BP_6 PF13458.6 CDJ94963.1 - 0.023 14.4 0.6 0.087 12.5 0.6 1.8 1 1 0 1 1 1 0 Periplasmic binding protein DUF745 PF05335.13 CDJ94963.1 - 0.2 11.4 1.3 0.28 10.9 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Sulfatase PF00884.23 CDJ94964.1 - 2.2e-66 224.3 0.2 2.6e-66 224.1 0.2 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CDJ94964.1 - 0.0044 16.6 0.1 0.36 10.4 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Ras PF00071.22 CDJ94965.1 - 1.4e-24 86.5 0.1 2.7e-22 79.1 0.0 2.2 2 0 0 2 2 2 2 Ras family zf-RING_UBOX PF13445.6 CDJ94965.1 - 6.2e-07 29.3 5.3 2.4e-06 27.5 5.3 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDJ94965.1 - 8.2e-07 29.1 6.2 8.2e-07 29.1 6.2 2.0 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 CDJ94965.1 - 8.6e-06 25.5 5.2 8.6e-06 25.5 5.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ94965.1 - 5e-05 23.1 8.4 0.00047 20.0 4.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ94965.1 - 0.00023 21.1 5.3 0.00023 21.1 5.3 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CDJ94965.1 - 0.00058 19.6 6.2 0.00058 19.6 6.2 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CDJ94965.1 - 0.0086 15.9 2.5 1 9.2 0.1 2.6 2 0 0 2 2 2 2 RING/Ubox like zinc-binding domain RsgA_GTPase PF03193.16 CDJ94965.1 - 0.02 14.8 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Roc PF08477.13 CDJ94965.1 - 0.024 14.9 0.3 12 6.2 0.0 2.4 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase potato_inhibit PF00280.18 CDJ94965.1 - 0.043 14.5 0.0 0.1 13.3 0.0 1.6 1 0 0 1 1 1 0 Potato inhibitor I family AAA_24 PF13479.6 CDJ94965.1 - 0.18 11.5 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf-RING_2 PF13639.6 CDJ94965.1 - 1.5 9.2 11.2 0.28 11.5 5.0 2.9 3 0 0 3 3 3 0 Ring finger domain Hint PF01079.20 CDJ94966.1 - 6.6e-22 78.1 0.0 7.3e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 Hint module DUF2408 PF10303.9 CDJ94966.1 - 0.047 14.3 0.0 0.055 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Uricase PF01014.18 CDJ94966.1 - 0.13 12.5 0.1 0.16 12.3 0.1 1.2 1 0 0 1 1 1 0 Uricase DGC PF08859.11 CDJ94967.1 - 0.0026 17.9 0.8 2.7 8.1 0.1 2.5 2 0 0 2 2 2 2 DGC domain Viral_env_E26 PF11050.8 CDJ94967.1 - 0.014 14.8 0.1 4.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Virus envelope protein E26 BACK PF07707.15 CDJ94967.1 - 0.04 14.0 0.1 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 BTB And C-terminal Kelch AfaD PF05775.12 CDJ94967.1 - 0.059 13.8 0.0 18 5.8 0.0 2.6 2 0 0 2 2 2 0 Enterobacteria AfaD invasin protein UPF0515 PF15135.6 CDJ94967.1 - 0.062 12.7 3.7 2.5 7.4 0.3 2.5 2 0 0 2 2 2 0 Uncharacterised protein UPF0515 Elongin_A PF06881.11 CDJ94967.1 - 0.18 12.4 2.4 3.7 8.1 0.2 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A E1-E2_ATPase PF00122.20 CDJ94968.1 - 7.3e-43 146.2 0.1 2e-42 144.8 0.1 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CDJ94968.1 - 5.6e-22 79.1 0.2 1.3e-12 48.5 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 CDJ94968.1 - 3.6e-13 49.7 3.4 5.2e-13 49.2 0.7 2.7 2 1 0 2 2 2 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.26 CDJ94968.1 - 8.9e-06 25.3 0.0 1.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CDJ94968.1 - 0.00013 21.9 0.0 0.00032 20.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) RVT_1 PF00078.27 CDJ94969.1 - 1.8e-38 132.3 0.0 2.4e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDJ94970.1 - 0.016 15.5 0.9 0.031 14.5 0.3 1.9 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ94970.1 - 0.15 12.1 1.7 0.16 12.0 0.4 1.7 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Exo_endo_phos_2 PF14529.6 CDJ94971.1 - 1.4e-06 28.1 0.0 2.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF5615 PF18480.1 CDJ94971.1 - 0.069 12.9 0.0 3.1 7.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) Exo_endo_phos PF03372.23 CDJ94971.1 - 0.098 12.2 0.0 0.23 11.0 0.0 1.6 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Ribosomal_S5 PF00333.20 CDJ94971.1 - 0.12 12.4 0.8 0.25 11.4 0.1 1.9 2 0 0 2 2 2 0 Ribosomal protein S5, N-terminal domain Aa_trans PF01490.18 CDJ94972.1 - 5.4e-64 216.4 23.0 7.5e-64 215.9 23.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RPS31 PF17067.5 CDJ94972.1 - 0.044 14.0 1.4 0.11 12.6 1.4 1.6 1 0 0 1 1 1 0 Ribosomal protein S31e RAMP4 PF06624.12 CDJ94972.1 - 0.086 12.9 0.9 0.26 11.4 0.9 1.9 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 MADF_DNA_bdg PF10545.9 CDJ94973.1 - 1.3e-14 54.3 1.9 4.7e-11 42.9 0.0 2.7 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4440 PF14534.6 CDJ94975.1 - 5.5e-05 23.5 0.2 0.00051 20.4 0.2 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) NopRA1 PF16201.5 CDJ94975.1 - 0.15 11.6 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 adh_short PF00106.25 CDJ94976.1 - 5.3e-30 104.3 0.1 8.9e-30 103.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ94976.1 - 1.2e-20 74.1 0.1 1.7e-20 73.6 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ94976.1 - 1.7e-06 28.1 0.1 2.8e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CDJ94976.1 - 1.9e-06 27.9 0.1 3.8e-06 26.9 0.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding ATP-synt_F PF01990.17 CDJ94976.1 - 0.00019 21.7 0.0 0.00042 20.6 0.0 1.5 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Epimerase PF01370.21 CDJ94976.1 - 0.00087 18.8 0.2 0.001 18.6 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 CDJ94976.1 - 0.0014 18.2 0.2 0.0023 17.5 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 CDJ94976.1 - 0.0026 16.8 0.1 0.0037 16.3 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 CDJ94976.1 - 0.0086 16.3 0.1 0.018 15.3 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain Sre PF03125.18 CDJ94980.1 - 2e-10 40.4 7.1 3e-10 39.8 6.9 1.4 1 1 1 2 2 2 1 C. elegans Sre G protein-coupled chemoreceptor 7TM_GPCR_Srab PF10292.9 CDJ94980.1 - 4e-05 22.7 1.0 4.5e-05 22.5 1.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor FixP_N PF14715.6 CDJ94980.1 - 0.049 13.4 1.1 3.2 7.6 0.1 2.4 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Sre PF03125.18 CDJ94981.1 - 2.4e-08 33.5 4.3 3e-08 33.2 4.3 1.2 1 0 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor 7TM_GPCR_Srab PF10292.9 CDJ94981.1 - 2.6e-05 23.3 2.0 3.2e-05 23.0 2.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor Sre PF03125.18 CDJ94982.1 - 8.4e-07 28.5 3.5 9.5e-07 28.3 3.5 1.0 1 0 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor 7TM_GPCR_Srab PF10292.9 CDJ94982.1 - 1.2e-05 24.4 1.5 1.4e-05 24.2 1.5 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor DUF2207 PF09972.9 CDJ94982.1 - 0.15 10.8 1.6 0.18 10.5 1.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sre PF03125.18 CDJ94983.1 - 5.6e-14 52.1 1.6 6.1e-14 52.0 1.6 1.0 1 0 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor 7TM_GPCR_Srab PF10292.9 CDJ94983.1 - 0.003 16.5 0.2 0.0037 16.2 0.2 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor Sre PF03125.18 CDJ94984.1 - 1.5e-12 47.4 0.2 1.6e-12 47.2 0.2 1.0 1 0 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor 7TM_GPCR_Srab PF10292.9 CDJ94984.1 - 0.0036 16.3 0.1 0.0042 16.1 0.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor Sre PF03125.18 CDJ94985.1 - 9.2e-12 44.8 2.3 1e-11 44.6 2.3 1.1 1 0 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor Clc-like PF07062.12 CDJ94985.1 - 0.087 12.3 2.4 0.1 12.0 2.4 1.1 1 0 0 1 1 1 0 Clc-like 7TM_GPCR_Srab PF10292.9 CDJ94986.1 - 3.5e-23 82.0 6.5 3.8e-23 81.9 6.5 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Sra PF02117.16 CDJ94986.1 - 1.4e-14 53.7 10.4 1.6e-14 53.5 10.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sra 7TM_GPCR_Srb PF02175.16 CDJ94986.1 - 0.00028 20.7 1.1 0.00028 20.7 1.1 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srb Erv26 PF04148.13 CDJ94986.1 - 0.08 12.7 7.8 0.12 12.2 7.8 1.2 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 7TM_GPCR_Srab PF10292.9 CDJ94987.1 - 7.8e-14 51.3 0.8 1.9e-13 50.1 0.8 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Sra PF02117.16 CDJ94987.1 - 9.4e-05 21.4 5.9 0.00015 20.7 5.9 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sra 7TM_GPCR_Srab PF10292.9 CDJ94988.1 - 3.6e-08 32.7 2.6 4.3e-08 32.5 2.6 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Sra PF02117.16 CDJ94988.1 - 2.1e-06 26.8 5.2 2.2e-06 26.7 5.2 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sra DUF3951 PF13131.6 CDJ94988.1 - 5.4 7.3 10.1 1.2 9.4 2.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) GEMIN8 PF15348.6 CDJ94989.1 - 6.1e-23 82.3 12.8 6.1e-23 82.3 12.8 3.1 2 1 1 3 3 3 2 Gemini of Cajal bodies-associated protein 8 GKAP PF03359.13 CDJ94989.1 - 1.3e-20 74.3 7.0 1.3e-20 74.3 7.0 2.2 2 0 0 2 2 2 1 Guanylate-kinase-associated protein (GKAP) protein PDCD2_C PF04194.13 CDJ94989.1 - 1.1 9.3 11.8 2 8.5 3.1 2.8 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain RVT_1 PF00078.27 CDJ94991.1 - 4.6e-45 153.8 0.0 6.6e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tyrosinase PF00264.20 CDJ94995.1 - 1.1e-17 65.1 0.1 4.9e-16 59.7 0.1 2.1 1 1 0 1 1 1 1 Common central domain of tyrosinase TDP43_N PF18694.1 CDJ94996.1 - 1.8e-24 85.4 0.0 3.6e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain RRM_1 PF00076.22 CDJ94996.1 - 9.4e-19 67.0 2.0 2.2e-08 33.8 0.2 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 CDJ94996.1 - 0.077 12.7 0.3 0.87 9.3 0.0 2.8 3 0 0 3 3 3 0 Ribonuclease B OB domain Gp-FAR-1 PF05823.12 CDJ94998.1 - 0.068 13.5 0.1 0.078 13.3 0.1 1.3 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) betaPIX_CC PF16523.5 CDJ94999.1 - 0.017 14.9 0.5 0.56 10.1 0.3 2.2 2 0 0 2 2 2 0 betaPIX coiled coil zf-CCHC_4 PF14392.6 CDJ94999.1 - 0.11 12.2 0.8 0.11 12.2 0.8 2.0 2 0 0 2 2 2 0 Zinc knuckle Collagen PF01391.18 CDJ95000.1 - 1.6e-26 91.8 107.1 2.2e-10 40.1 37.6 4.0 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ95000.1 - 0.16 12.1 0.0 0.2 11.8 0.0 1.1 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain SPO22 PF08631.10 CDJ95001.1 - 0.073 12.6 0.8 0.22 11.0 0.5 1.6 1 1 1 2 2 2 0 Meiosis protein SPO22/ZIP4 like RVT_1 PF00078.27 CDJ95002.1 - 2.2e-10 40.4 0.0 6.6e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) FAP PF07174.11 CDJ95004.1 - 0.67 9.4 12.1 0.75 9.2 12.1 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) RVT_1 PF00078.27 CDJ95005.1 - 7.3e-10 38.7 0.0 7.9e-10 38.6 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GFA PF04828.14 CDJ95006.1 - 5.2e-10 39.5 5.2 5.2e-10 39.5 5.2 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme CAP PF00188.26 CDJ95007.1 - 3.8e-07 31.0 3.6 4.6e-07 30.7 3.6 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ95007.1 - 0.00045 20.5 2.1 0.0011 19.2 2.0 1.7 1 1 0 1 1 1 1 Ancylostoma-associated secreted protein related ATP-synt_F6 PF05511.11 CDJ95007.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 CAP PF00188.26 CDJ95008.1 - 7.1e-17 62.4 5.9 1e-16 61.9 5.9 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ95008.1 - 0.00063 20.0 7.4 0.012 15.9 7.1 2.5 1 1 1 2 2 2 1 Ancylostoma-associated secreted protein related SpoVG PF04026.12 CDJ95009.1 - 0.0023 18.1 0.1 0.043 14.0 0.1 2.3 1 1 0 1 1 1 1 SpoVG Peptidase_M16_M PF16187.5 CDJ95010.1 - 3.8e-28 98.6 0.0 8.7e-28 97.4 0.0 1.6 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 CDJ95010.1 - 6.9e-09 36.0 0.1 1.4e-08 35.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Osmo_CC PF08946.10 CDJ95010.1 - 0.45 10.8 2.0 1.1 9.6 0.7 2.3 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Globin PF00042.22 CDJ95011.1 - 3.6e-06 27.5 0.0 5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Globin YoeB_toxin PF06769.14 CDJ95014.1 - 0.0015 18.5 1.6 0.004 17.1 1.5 1.6 1 1 0 1 1 1 1 YoeB-like toxin of bacterial type II toxin-antitoxin system DUF5305 PF17231.2 CDJ95015.1 - 0.066 12.6 0.0 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) GvpK PF05121.12 CDJ95015.1 - 0.12 12.5 0.0 0.41 10.7 0.0 1.8 2 0 0 2 2 2 0 Gas vesicle protein K TPR_1 PF00515.28 CDJ95016.1 - 2.6e-06 27.0 0.0 6.1e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ95016.1 - 1.3e-05 24.9 0.1 0.0018 18.2 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ95016.1 - 4.1e-05 23.5 0.1 0.0088 16.2 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ95016.1 - 0.00019 21.7 0.9 0.00076 19.7 0.8 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ95016.1 - 0.00035 20.4 0.3 0.0025 17.7 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ95016.1 - 0.00079 19.6 0.0 0.002 18.4 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ95016.1 - 0.023 14.6 0.4 0.081 12.8 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ95016.1 - 0.08 13.6 0.1 0.95 10.2 0.5 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 CDJ95016.1 - 0.088 13.2 0.0 0.42 11.0 0.0 1.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ95016.1 - 0.11 13.0 0.1 0.31 11.6 0.1 1.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ95016.1 - 0.15 11.8 0.1 1 9.1 0.0 2.1 1 1 0 2 2 2 0 TPR repeat Ald_Xan_dh_C2 PF02738.18 CDJ95017.1 - 8.3e-183 608.8 0.0 1.2e-182 608.3 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 CDJ95017.1 - 2e-41 141.6 0.0 3.7e-41 140.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 CDJ95017.1 - 1.1e-31 108.7 0.6 2.2e-30 104.5 0.1 2.7 2 0 0 2 2 2 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 CDJ95017.1 - 7.3e-30 103.2 0.0 9.6e-29 99.6 0.0 2.6 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 CDJ95017.1 - 1.3e-29 102.8 0.4 3e-29 101.6 0.4 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.27 CDJ95017.1 - 3.2e-07 30.2 0.3 3.2e-07 30.2 0.3 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Sulfotransfer_3 PF13469.6 CDJ95017.1 - 0.1 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase family ABC2_membrane_3 PF12698.7 CDJ95019.1 - 4e-45 154.4 48.1 1.3e-29 103.4 21.6 2.5 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 CDJ95019.1 - 4e-42 144.0 0.1 3e-29 102.3 0.1 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CDJ95019.1 - 4.6e-17 62.8 0.0 7.6e-06 25.9 0.0 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDJ95019.1 - 1.5e-05 24.5 1.0 0.13 11.7 1.0 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CDJ95019.1 - 0.011 16.3 0.2 0.026 15.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 CDJ95019.1 - 0.024 14.9 0.0 10 6.5 0.0 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 CDJ95019.1 - 0.06 13.0 0.0 8 6.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 CDJ95019.1 - 0.073 12.8 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1759 PF03564.15 CDJ95021.1 - 5.4e-14 52.4 0.9 7.8e-14 51.8 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) MG3 PF17791.1 CDJ95021.1 - 0.055 13.7 0.0 0.14 12.5 0.0 1.7 1 1 0 1 1 1 0 Macroglobulin domain MG3 Herpes_UL47 PF03362.13 CDJ95021.1 - 0.059 12.2 0.0 0.2 10.4 0.0 1.7 2 0 0 2 2 2 0 Herpesvirus UL47 protein DUF3545 PF12065.8 CDJ95021.1 - 0.12 12.4 1.6 0.34 10.9 1.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3545) ubiquitin PF00240.23 CDJ95022.1 - 1.1e-07 31.4 0.1 1.7e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_5 PF18037.1 CDJ95022.1 - 0.015 15.7 0.1 0.026 14.9 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain ubiquitin PF00240.23 CDJ95023.1 - 0.074 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family Pex14_N PF04695.13 CDJ95023.1 - 3.7 8.2 12.0 1.6 9.4 3.1 2.6 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DER1 PF04511.15 CDJ95024.1 - 1.4e-70 237.1 13.2 1.8e-70 236.8 13.2 1.1 1 0 0 1 1 1 1 Der1-like family Ribosomal_S21e PF01249.18 CDJ95024.1 - 6.7e-34 115.9 0.0 9.5e-34 115.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S21e DUF1981 PF09324.10 CDJ95025.1 - 1.5e-10 40.7 0.0 3.8e-09 36.3 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) Sec7_N PF12783.7 CDJ95025.1 - 0.062 13.2 0.7 0.26 11.2 0.3 2.4 2 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal RVT_1 PF00078.27 CDJ95026.1 - 7.1e-06 25.7 0.0 1.6e-05 24.5 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) fn3 PF00041.21 CDJ95027.1 - 1.6e-20 73.2 2.1 4.2e-11 43.0 0.1 3.1 3 0 0 3 3 3 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CDJ95027.1 - 0.00023 21.7 1.5 0.016 15.8 0.4 2.6 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain GPI-anchored PF10342.9 CDJ95027.1 - 0.04 14.7 1.0 0.16 12.7 0.2 2.2 3 0 0 3 3 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Lectin_C PF00059.21 CDJ95028.1 - 2.8e-14 53.8 0.1 3.5e-14 53.4 0.1 1.1 1 0 0 1 1 1 1 Lectin C-type domain Aa_trans PF01490.18 CDJ95029.1 - 1.2e-66 225.1 30.7 8.1e-55 186.2 15.1 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Glutaredoxin PF00462.24 CDJ95031.1 - 1.9e-06 28.0 2.6 6.3e-06 26.3 0.1 2.6 2 0 0 2 2 2 1 Glutaredoxin SH3BGR PF04908.15 CDJ95031.1 - 0.013 15.7 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein DnaJ_CXXCXGXG PF00684.19 CDJ95031.1 - 0.29 11.5 12.6 0.29 11.5 3.7 2.1 1 1 1 2 2 2 0 DnaJ central domain Anti-TRAP PF15777.5 CDJ95031.1 - 3.1 7.8 9.9 2.5 8.1 2.7 2.7 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Kinesin PF00225.23 CDJ95032.1 - 1.8e-121 405.2 0.6 3.2e-121 404.3 0.6 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ95032.1 - 2.4e-25 89.2 0.4 6.5e-25 87.8 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding Jnk-SapK_ap_N PF09744.9 CDJ95032.1 - 0.33 11.2 41.7 0.12 12.6 16.9 2.8 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 CRA PF06589.11 CDJ95032.1 - 0.49 10.5 2.8 1.2 9.3 2.8 1.7 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) AAA_22 PF13401.6 CDJ95032.1 - 3.8 7.8 0.0 3.8 7.8 0.0 3.6 2 1 0 3 3 3 0 AAA domain HIP1_clath_bdg PF16515.5 CDJ95032.1 - 7.8 7.2 40.2 0.53 10.9 15.1 3.5 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PIP5K PF01504.18 CDJ95033.1 - 2.5e-100 335.2 0.0 2e-60 204.4 0.0 2.2 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase DUF2564 PF10819.8 CDJ95033.1 - 0.014 15.8 0.5 8 6.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) tRNA-synt_2 PF00152.20 CDJ95034.1 - 3.8e-74 249.6 0.0 5.5e-74 249.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CDJ95034.1 - 5.9e-09 35.8 1.1 1.2e-08 34.8 1.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CDJ95034.1 - 0.0017 17.9 0.1 0.62 9.5 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) TMEM52 PF14979.6 CDJ95035.1 - 0.054 13.4 0.3 0.063 13.2 0.3 1.2 1 0 0 1 1 1 0 Transmembrane 52 PDR_assoc PF08370.11 CDJ95035.1 - 0.097 12.4 0.5 0.18 11.6 0.5 1.4 1 1 0 1 1 1 0 Plant PDR ABC transporter associated Cadherin_C_2 PF16492.5 CDJ95036.1 - 0.13 13.1 0.0 0.14 12.9 0.0 1.1 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal TMIE PF16038.5 CDJ95036.1 - 0.73 9.7 4.2 1 9.2 4.2 1.2 1 0 0 1 1 1 0 TMIE protein AMP-binding PF00501.28 CDJ95037.1 - 2e-77 260.6 0.0 2.4e-77 260.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ95037.1 - 0.00025 21.9 0.0 0.00057 20.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain F-box-like PF12937.7 CDJ95038.1 - 1.3e-07 31.4 0.0 3.7e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 CDJ95038.1 - 5.3e-06 26.2 0.1 4.1e-05 23.3 0.1 2.2 1 1 0 1 1 1 1 F-box domain F-box-like_2 PF13013.6 CDJ95038.1 - 0.083 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain DUF273 PF03314.14 CDJ95040.1 - 4.2e-25 88.6 0.0 7.5e-25 87.8 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function, DUF273 Nucleotid_trans PF03407.16 CDJ95040.1 - 0.0011 19.0 0.0 0.0011 19.0 0.0 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase PhoU PF01895.19 CDJ95041.1 - 0.0019 18.6 2.0 0.011 16.2 0.9 2.0 1 1 1 2 2 2 1 PhoU domain HTH_24 PF13412.6 CDJ95041.1 - 0.9 9.2 0.1 0.9 9.2 0.1 2.5 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding Beta_elim_lyase PF01212.21 CDJ95042.1 - 5.1e-100 334.5 2.4 6.2e-100 334.3 2.4 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 CDJ95042.1 - 1.1e-13 51.1 0.0 1.3e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CDJ95042.1 - 3.3e-10 39.8 0.1 2.4e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 CDJ95042.1 - 9.9e-07 27.6 0.0 1.4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 CDJ95042.1 - 0.00024 20.0 0.0 0.0016 17.2 0.0 2.0 2 0 0 2 2 2 1 Orn/Lys/Arg decarboxylase, major domain tRNA_anti-codon PF01336.25 CDJ95043.1 - 0.049 13.6 0.0 0.079 13.0 0.0 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain tRNA_anti-codon PF01336.25 CDJ95044.1 - 0.05 13.6 0.0 0.079 13.0 0.0 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DM PF00751.18 CDJ95045.1 - 1.8e-19 69.3 8.9 1.8e-19 69.3 8.9 1.6 2 0 0 2 2 2 1 DM DNA binding domain WD40 PF00400.32 CDJ95046.1 - 6.6e-32 109.0 34.4 3.5e-06 27.6 0.2 11.8 13 0 0 13 13 13 7 WD domain, G-beta repeat Utp13 PF08625.11 CDJ95046.1 - 7.8e-13 48.5 0.4 1.7e-12 47.4 0.4 1.6 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 CDJ95046.1 - 1.5e-09 38.0 4.9 0.035 14.4 0.0 7.7 4 2 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain UTP15_C PF09384.10 CDJ95046.1 - 6.7e-06 25.9 1.0 1.3e-05 24.9 1.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal Ge1_WD40 PF16529.5 CDJ95046.1 - 0.00081 18.4 4.5 0.92 8.4 0.0 4.4 3 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 CDJ95046.1 - 0.0073 15.4 0.0 0.22 10.5 0.0 2.3 2 0 0 2 2 2 1 VID27 C-terminal WD40-like domain PALB2_WD40 PF16756.5 CDJ95046.1 - 0.019 13.9 1.9 0.68 8.8 0.3 2.9 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain PQQ_2 PF13360.6 CDJ95046.1 - 0.037 13.6 2.4 1.3 8.5 0.0 3.0 3 1 0 3 3 3 0 PQQ-like domain Glyco_transf_7N PF13733.6 CDJ95047.1 - 2.5e-44 150.1 0.0 4.2e-44 149.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CDJ95047.1 - 1.6e-26 91.7 0.7 2.7e-26 91.0 0.7 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase F-box-like PF12937.7 CDJ95048.1 - 1.1e-06 28.4 0.0 2.7e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 CDJ95048.1 - 1.3e-05 25.5 4.4 1.9 9.0 0.1 4.7 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) F-box PF00646.33 CDJ95048.1 - 0.0057 16.5 6.8 0.38 10.7 1.0 3.9 3 1 0 3 3 3 2 F-box domain tRNA_anti-codon PF01336.25 CDJ95050.1 - 0.048 13.7 0.0 0.078 13.0 0.0 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain tRNA_anti-codon PF01336.25 CDJ95051.1 - 0.048 13.7 0.0 0.078 13.0 0.0 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Ras PF00071.22 CDJ95053.1 - 5.5e-08 32.6 1.9 7.3e-06 25.7 0.2 2.1 1 1 1 2 2 2 2 Ras family RsgA_GTPase PF03193.16 CDJ95053.1 - 3.1e-06 27.2 0.4 0.0014 18.6 0.2 2.1 2 0 0 2 2 2 2 RsgA GTPase ABC_tran PF00005.27 CDJ95053.1 - 0.00011 22.7 0.1 0.0002 21.9 0.1 1.6 1 1 0 1 1 1 1 ABC transporter Arf PF00025.21 CDJ95053.1 - 0.00035 20.1 0.5 0.0057 16.1 0.5 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDJ95053.1 - 0.0025 17.4 0.5 0.6 9.6 0.2 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Zeta_toxin PF06414.12 CDJ95053.1 - 0.0054 16.0 0.0 0.24 10.6 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin Roc PF08477.13 CDJ95053.1 - 0.012 15.8 1.0 5.1 7.3 0.1 2.7 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 CDJ95053.1 - 0.014 14.6 0.2 0.098 11.9 0.0 1.9 1 1 0 2 2 2 0 Septin AAA_29 PF13555.6 CDJ95053.1 - 0.026 14.3 0.0 0.066 13.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ClpS PF02617.17 CDJ95053.1 - 0.05 13.4 0.1 1.5 8.7 0.1 2.3 2 0 0 2 2 2 0 ATP-dependent Clp protease adaptor protein ClpS AAA_24 PF13479.6 CDJ95053.1 - 0.067 12.9 0.1 0.095 12.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 CDJ95053.1 - 0.098 11.7 0.0 0.29 10.2 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 CDJ95053.1 - 0.12 11.6 0.2 0.48 9.7 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.6 CDJ95053.1 - 0.13 12.6 0.6 0.35 11.1 0.6 1.9 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 CDJ95053.1 - 0.15 11.2 2.6 0.55 9.3 2.6 2.0 1 1 0 1 1 1 0 G-protein alpha subunit AAA_23 PF13476.6 CDJ95053.1 - 0.18 12.3 2.4 0.27 11.7 0.5 1.9 2 0 0 2 2 2 0 AAA domain UPF0242 PF06785.11 CDJ95054.1 - 0.3 11.2 1.0 0.37 10.9 1.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DRIM PF07539.12 CDJ95055.1 - 2.8e-86 290.2 2.4 4.4e-86 289.6 1.5 1.7 2 0 0 2 2 2 1 Down-regulated in metastasis TOM20_plant PF06552.12 CDJ95056.1 - 0.021 14.5 2.0 0.043 13.6 2.0 1.4 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 HTH_50 PF18024.1 CDJ95057.1 - 0.00038 20.0 0.0 0.00066 19.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 CDJ95057.1 - 0.0059 16.1 0.0 0.0098 15.4 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_32 PF13565.6 CDJ95057.1 - 0.018 15.7 0.0 0.036 14.7 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_IS630 PF01710.16 CDJ95057.1 - 0.021 14.8 0.0 0.033 14.2 0.0 1.2 1 0 0 1 1 1 0 Transposase IF2_N PF04760.15 CDJ95057.1 - 0.057 13.2 0.3 0.13 12.2 0.2 1.6 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region HTH_23 PF13384.6 CDJ95057.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_10 PF04967.12 CDJ95057.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain DUF1673 PF07895.11 CDJ95057.1 - 0.077 12.7 1.2 0.12 12.0 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Sigma70_r4 PF04545.16 CDJ95057.1 - 0.09 12.3 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_38 PF13936.6 CDJ95057.1 - 0.095 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 CDJ95057.1 - 0.15 11.9 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain MarR PF01047.22 CDJ95057.1 - 0.16 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 MarR family Motile_Sperm PF00635.26 CDJ95058.1 - 0.0045 16.8 0.3 0.0095 15.8 0.3 1.6 1 1 0 1 1 1 1 MSP (Major sperm protein) domain Transposase_1 PF01359.18 CDJ95059.1 - 1.1e-25 89.3 2.2 1.8e-25 88.5 2.2 1.4 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_48 PF17906.1 CDJ95059.1 - 6.5e-08 32.6 0.1 1.2e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase DDE_3 PF13358.6 CDJ95059.1 - 5.3e-06 26.2 0.4 7.9e-06 25.7 0.4 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease PfkB PF00294.24 CDJ95061.1 - 3e-27 95.7 0.0 5.7e-27 94.8 0.0 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase VQ PF05678.14 CDJ95061.1 - 0.021 14.3 0.6 0.048 13.2 0.6 1.6 1 0 0 1 1 1 0 VQ motif RVT_1 PF00078.27 CDJ95062.1 - 2.2e-34 118.9 0.1 4.9e-34 117.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDJ95062.1 - 3.4e-06 26.9 0.0 1.1e-05 25.2 0.0 2.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ95062.1 - 9.6e-05 22.0 0.1 0.0002 21.0 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Indigoidine_A PF04227.12 CDJ95063.1 - 3.7e-115 384.3 0.9 4.5e-115 384.0 0.9 1.1 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 CDJ95063.1 - 0.0017 17.7 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase SARAF PF06682.12 CDJ95064.1 - 9.3e-79 265.5 0.0 1.1e-78 265.2 0.0 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis PLDc PF00614.22 CDJ95065.1 - 1e-16 60.3 1.0 8.7e-08 32.0 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PX PF00787.24 CDJ95065.1 - 7.8e-12 45.2 0.7 1.7e-05 24.7 0.1 2.4 2 0 0 2 2 2 2 PX domain PLDc_2 PF13091.6 CDJ95065.1 - 2.7e-10 40.2 0.2 0.00016 21.5 0.0 3.4 4 0 0 4 4 4 2 PLD-like domain CNOT1_HEAT PF16418.5 CDJ95066.1 - 2.6e-23 82.7 0.6 1.8e-22 80.1 0.1 2.5 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat RPN6_N PF18055.1 CDJ95067.1 - 8.5e-28 97.1 0.4 2.3e-27 95.7 0.4 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 CDJ95067.1 - 2.2e-16 60.3 0.1 7.1e-16 58.6 0.0 2.0 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 CDJ95067.1 - 6.9e-13 48.1 0.1 1.5e-12 47.0 0.1 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain DUF5397 PF17375.2 CDJ95067.1 - 0.032 13.9 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5397) Vps53_N PF04100.12 CDJ95067.1 - 0.037 13.0 0.2 0.11 11.5 0.1 1.9 2 0 0 2 2 2 0 Vps53-like, N-terminal RIO1 PF01163.22 CDJ95068.1 - 7.8e-61 205.0 0.0 2.1e-60 203.6 0.0 1.7 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 CDJ95068.1 - 1.1e-05 24.9 0.0 2.6e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 CDJ95068.1 - 0.00095 19.2 0.1 0.014 15.4 0.0 2.7 2 2 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ95068.1 - 0.014 14.2 0.1 0.014 14.2 0.1 2.0 2 1 0 2 2 2 0 Fungal protein kinase Nucleolin_bd PF16725.5 CDJ95068.1 - 0.062 13.0 0.5 1.1 9.0 0.3 2.7 1 1 1 2 2 2 0 Nucleolin binding domain Choline_kinase PF01633.20 CDJ95068.1 - 0.27 10.8 3.3 1.4 8.4 0.8 3.0 2 1 1 3 3 3 0 Choline/ethanolamine kinase PAN_1 PF00024.26 CDJ95069.1 - 2.2e-05 24.3 0.7 3.8e-05 23.6 0.7 1.4 1 0 0 1 1 1 1 PAN domain LDcluster4 PF18306.1 CDJ95069.1 - 0.1 12.2 0.0 0.77 9.3 0.0 2.0 2 0 0 2 2 2 0 SLOG cluster4 family Neur_chan_LBD PF02931.23 CDJ95070.1 - 7.7e-36 123.6 0.1 1.1e-35 123.0 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ95070.1 - 5.3e-29 102.0 1.8 2.6e-24 86.6 0.2 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Collagen PF01391.18 CDJ95072.1 - 3.4e-11 42.7 29.9 1.3e-05 24.9 11.7 2.1 2 0 0 2 2 2 2 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ95072.1 - 4.6e-08 33.0 0.1 7.2e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain UCH PF00443.29 CDJ95074.1 - 6.3e-28 98.0 0.0 1.2e-27 97.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 CDJ95074.1 - 1.6e-21 75.8 2.2 3.9e-21 74.6 2.2 1.7 1 0 0 1 1 1 1 Variant UBP zinc finger zf-UBP PF02148.19 CDJ95074.1 - 2.3e-06 27.8 4.5 2.8e-05 24.4 0.3 2.9 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 CDJ95074.1 - 0.012 15.2 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase PAF-AH_p_II PF03403.13 CDJ95075.1 - 5.2e-81 272.1 0.0 8e-81 271.5 0.0 1.2 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 CDJ95075.1 - 2.2e-07 30.1 0.0 8.9e-07 28.1 0.0 1.9 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 CDJ95075.1 - 1.8e-05 24.1 0.1 0.043 13.1 0.1 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 CDJ95075.1 - 3.5e-05 23.0 0.1 0.003 16.6 0.1 2.1 2 0 0 2 2 2 1 Chlorophyllase Peptidase_S9 PF00326.21 CDJ95075.1 - 0.008 15.7 0.1 0.023 14.2 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CDJ95075.1 - 0.035 13.7 1.3 0.29 10.7 1.3 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.12 CDJ95075.1 - 0.039 12.6 0.0 0.064 11.9 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DLH PF01738.18 CDJ95075.1 - 0.04 13.5 0.0 0.47 10.0 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family mRNA_cap_C PF03919.15 CDJ95075.1 - 0.094 13.4 0.2 0.27 11.9 0.1 1.8 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain Abhydrolase_6 PF12697.7 CDJ95075.1 - 0.11 13.1 0.3 0.31 11.6 0.3 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 CDJ95075.1 - 0.2 11.4 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Filamin PF00630.19 CDJ95076.1 - 9.1e-145 472.9 4.7 2.2e-17 63.8 0.0 15.3 15 0 0 15 15 15 15 Filamin/ABP280 repeat Big_3_5 PF16640.5 CDJ95076.1 - 9.4e-11 41.8 3.6 2.1 8.6 0.0 9.4 11 0 0 11 11 11 2 Bacterial Ig-like domain (group 3) DUF5060 PF16586.5 CDJ95076.1 - 2.9e-08 34.0 0.5 0.92 9.9 0.0 7.9 11 0 0 11 11 10 2 Domain of unknown function (DUF5060) Y_Y_Y PF07495.13 CDJ95076.1 - 7.3e-06 25.8 3.8 1.2 9.2 0.0 6.4 8 0 0 8 8 8 1 Y_Y_Y domain Invasin_D3 PF09134.10 CDJ95076.1 - 2.9e-05 24.3 0.7 22 5.4 0.0 8.5 9 1 1 10 10 10 0 Invasin, domain 3 Big_6 PF17936.1 CDJ95076.1 - 0.00093 19.4 11.2 37 4.7 0.1 9.7 9 2 3 12 12 12 0 Bacterial Ig domain CBM60 PF16841.5 CDJ95076.1 - 0.016 15.6 1.1 32 5.0 0.1 4.8 5 0 0 5 5 5 0 Ca-dependent carbohydrate-binding module xylan-binding EMP24_GP25L PF01105.24 CDJ95076.1 - 0.017 15.1 0.0 24 4.8 0.0 5.2 6 1 0 6 6 6 0 emp24/gp25L/p24 family/GOLD ASH PF15780.5 CDJ95076.1 - 0.035 14.3 0.1 20 5.5 0.0 5.0 5 0 0 5 5 5 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin FixH PF05751.11 CDJ95076.1 - 0.35 10.9 1.0 47 4.0 0.0 4.5 5 1 0 5 5 4 0 FixH YbbR PF07949.12 CDJ95076.1 - 4.4 7.7 7.0 15 6.0 0.0 4.9 5 0 0 5 5 5 0 YbbR-like protein HSP20 PF00011.21 CDJ95079.1 - 1.6e-18 66.8 0.4 6.4e-18 64.8 0.1 2.3 2 0 0 2 2 2 1 Hsp20/alpha crystallin family SprA-related PF12118.8 CDJ95079.1 - 0.093 11.9 11.3 0.15 11.2 11.3 1.2 1 0 0 1 1 1 0 SprA-related family Trypan_PARP PF05887.11 CDJ95079.1 - 1.4 8.9 11.7 2.7 8.0 11.7 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF16 PF01519.16 CDJ95080.1 - 0.22 12.0 8.3 1.8 9.1 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 zf-CpG_bind_C PF12269.8 CDJ95080.1 - 1.2 8.8 4.5 0.4 10.4 1.2 1.8 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain DUF1664 PF07889.12 CDJ95080.1 - 1.8 8.6 6.3 1.2 9.2 4.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-CCCH PF00642.24 CDJ95081.1 - 0.0001 22.1 6.4 0.0013 18.6 1.9 2.8 2 1 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 CDJ95081.1 - 0.0025 18.2 5.9 0.29 11.7 0.4 2.8 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 CDJ95081.1 - 0.0033 17.2 8.5 0.087 12.7 1.3 3.0 2 1 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 CDJ95081.1 - 0.026 14.7 0.5 0.044 14.0 0.5 1.3 1 0 0 1 1 1 0 Zinc-finger containing family ODV-E18 PF10717.9 CDJ95081.1 - 0.19 11.7 1.5 0.44 10.5 1.5 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 SP_C-Propep PF08999.10 CDJ95081.1 - 0.2 11.5 9.6 0.49 10.2 9.6 1.7 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Antifungal_prot PF11402.8 CDJ95081.1 - 0.28 11.5 4.2 1.4 9.3 4.2 2.0 1 1 0 1 1 1 0 Antifungal protein zf_CCCH_4 PF18345.1 CDJ95081.1 - 0.57 10.3 10.5 4 7.6 2.0 3.8 2 2 0 2 2 2 0 Zinc finger domain RVT_1 PF00078.27 CDJ95083.1 - 1.5e-23 83.5 0.0 2.9e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDJ95083.1 - 5.5e-11 42.4 0.0 1.9e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DNAPolymera_Pol PF11590.8 CDJ95083.1 - 0.0029 17.4 0.8 0.0047 16.8 0.1 1.7 2 0 0 2 2 2 1 DNA polymerase catalytic subunit Pol RT_RNaseH PF17917.1 CDJ95083.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.7 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase PNMA PF14893.6 CDJ95084.1 - 0.032 13.6 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 PNMA LodA_N PF17990.1 CDJ95084.1 - 0.089 12.7 0.1 12 5.8 0.0 2.2 1 1 0 2 2 2 0 L-Lysine epsilon oxidase N-terminal SAM_1 PF00536.30 CDJ95085.1 - 1e-15 57.9 0.1 1.7e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CDJ95085.1 - 3.3e-15 56.0 0.1 6.2e-15 55.1 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TIR_2 PF13676.6 CDJ95085.1 - 8.6e-05 23.1 0.0 0.00015 22.4 0.0 1.3 1 0 0 1 1 1 1 TIR domain SAM_3 PF18016.1 CDJ95085.1 - 0.011 15.6 0.2 0.066 13.0 0.0 2.3 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) Pkinase PF00069.25 CDJ95086.1 - 8.2e-32 110.6 0.0 1.3e-31 110.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ95086.1 - 6.9e-22 78.0 0.0 1.1e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ95086.1 - 7.3e-05 21.7 0.0 0.00013 20.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDJ95086.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Herpes_U34 PF04541.13 CDJ95087.1 - 0.042 13.1 0.6 0.055 12.7 0.6 1.1 1 0 0 1 1 1 0 Herpesvirus virion protein U34 ThiD2 PF17792.1 CDJ95087.1 - 0.093 13.2 0.4 5.8 7.4 0.1 2.1 2 0 0 2 2 2 0 ThiD2 family Thioredoxin_11 PF18078.1 CDJ95087.1 - 0.27 11.3 4.2 0.23 11.6 1.8 1.8 1 1 1 2 2 2 0 Thioredoxin-like SNTX domain RNase_J_C PF17770.1 CDJ95087.1 - 0.28 12.2 0.9 1.3 10.1 0.0 2.1 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain FAA_hydrolase_N PF09298.11 CDJ95087.1 - 0.3 11.3 1.8 0.6 10.3 0.4 1.9 1 1 1 2 2 2 0 Fumarylacetoacetase N-terminal FH2 PF02181.23 CDJ95088.1 - 3.5e-88 296.2 6.5 3.5e-88 296.2 6.5 1.7 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 CDJ95088.1 - 2.8e-34 118.4 0.2 2.8e-34 118.4 0.2 2.7 2 1 1 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 CDJ95088.1 - 7.4e-19 68.0 3.9 2.7e-18 66.2 0.8 3.0 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain DivIC PF04977.15 CDJ95088.1 - 0.011 15.5 3.5 0.052 13.3 0.1 3.4 3 0 0 3 3 3 0 Septum formation initiator DUF4129 PF13559.6 CDJ95088.1 - 0.025 14.8 0.0 0.094 13.0 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) YajC PF02699.15 CDJ95088.1 - 0.16 11.9 0.0 0.64 9.9 0.0 2.0 2 0 0 2 2 2 0 Preprotein translocase subunit DHHC PF01529.20 CDJ95089.1 - 3e-35 121.2 9.0 3e-35 121.2 9.0 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF3405 PF11885.8 CDJ95091.1 - 0.015 13.9 0.5 0.019 13.6 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) End3 PF12761.7 CDJ95092.1 - 0.016 15.4 6.8 0.026 14.7 2.6 2.1 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 EcoR124_C PF12008.8 CDJ95092.1 - 0.018 14.7 3.4 0.068 12.8 0.2 2.1 1 1 1 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal Occludin_ELL PF07303.13 CDJ95092.1 - 0.27 12.0 0.3 0.27 12.0 0.3 2.8 2 1 1 3 3 3 0 Occludin homology domain PKK PF12474.8 CDJ95092.1 - 3.4 7.8 9.7 0.74 9.9 5.7 1.9 1 1 1 2 2 2 0 Polo kinase kinase Arf PF00025.21 CDJ95095.1 - 3.4e-19 69.0 0.2 3.7e-19 68.8 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MeaB PF03308.16 CDJ95095.1 - 0.0056 15.7 0.1 0.006 15.6 0.1 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Tetraspanin PF00335.20 CDJ95096.1 - 0.0078 16.0 0.4 0.0078 16.0 0.4 2.8 2 1 0 2 2 2 1 Tetraspanin family DUF4131 PF13567.6 CDJ95096.1 - 0.1 12.2 0.1 0.1 12.2 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF2663 PF10864.8 CDJ95096.1 - 9 6.7 8.6 3.9 7.9 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2663) Ion_trans_2 PF07885.16 CDJ95097.1 - 1.3e-18 66.7 4.2 1.3e-18 66.7 4.2 2.0 2 0 0 2 2 2 1 Ion channel Lig_chan PF00060.26 CDJ95097.1 - 0.004 17.0 0.2 0.0065 16.3 0.2 1.5 1 1 0 1 1 1 1 Ligand-gated ion channel Ion_trans PF00520.31 CDJ95097.1 - 0.014 14.6 0.2 0.039 13.2 0.1 1.7 2 0 0 2 2 2 0 Ion transport protein DUF4668 PF15701.5 CDJ95097.1 - 0.041 13.7 0.3 0.072 12.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) Nop53 PF07767.11 CDJ95098.1 - 8e-56 190.1 39.1 1.6e-55 189.2 39.1 1.5 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF4666 PF15697.5 CDJ95098.1 - 7.2 7.3 8.1 0.63 10.8 2.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4666) zf-C2H2 PF00096.26 CDJ95099.1 - 2.9e-15 55.8 21.3 2.9e-05 24.3 1.7 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ95099.1 - 7e-12 45.2 17.7 2.4e-08 34.0 0.7 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDJ95099.1 - 4.4e-09 36.4 20.9 0.0018 19.0 1.3 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CDJ95099.1 - 1.6e-06 27.7 15.8 0.00011 21.9 3.0 3.5 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 CDJ95099.1 - 0.00069 19.8 10.5 0.089 13.1 0.5 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDJ95099.1 - 0.0011 19.3 12.5 0.0043 17.4 0.8 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_7 PF15269.6 CDJ95099.1 - 0.011 15.9 13.0 0.025 14.7 1.8 2.6 1 1 1 2 2 2 0 Zinc-finger zf-C2H2_2 PF12756.7 CDJ95099.1 - 0.017 15.4 13.2 0.77 10.1 13.2 3.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 CDJ95099.1 - 0.16 12.0 0.3 0.16 12.0 0.3 3.7 4 1 0 4 4 4 0 C2H2-type zinc finger zf-Di19 PF05605.12 CDJ95099.1 - 0.99 9.7 9.6 1.1 9.6 4.1 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Actin_micro PF17003.5 CDJ95099.1 - 1.7 7.7 5.8 3.8 6.6 0.3 2.6 1 1 1 2 2 2 0 Putative actin-like family zf-C2H2_11 PF16622.5 CDJ95099.1 - 5.3 6.9 13.1 0.32 10.8 0.3 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type Lactamase_B_6 PF16661.5 CDJ95101.1 - 4.2e-12 45.9 0.0 5.2e-10 39.1 0.0 2.6 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 CDJ95101.1 - 1.8e-07 31.4 0.0 4.7e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Beta_lactamase3 PF17030.5 CDJ95101.1 - 0.00036 19.8 0.0 0.0013 18.0 0.0 2.0 1 1 0 1 1 1 1 Putative beta-lactamase-like family RT_RNaseH PF17917.1 CDJ95102.1 - 2.3e-33 114.6 0.0 6.2e-33 113.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ95102.1 - 2.7e-33 114.0 0.6 5.9e-33 112.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ95102.1 - 2.1e-18 66.6 0.1 1.5e-16 60.7 0.0 3.0 3 0 0 3 3 3 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ95102.1 - 3.1e-16 59.2 1.5 5.1e-16 58.5 0.2 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 CDJ95102.1 - 1.8e-10 40.7 0.1 3.3e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 CDJ95102.1 - 0.043 13.6 0.0 0.14 12.0 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain gag-asp_proteas PF13975.6 CDJ95103.1 - 0.00093 19.7 0.0 0.0028 18.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease NPF PF16601.5 CDJ95104.1 - 0.24 11.9 0.0 0.35 11.3 0.0 1.2 1 0 0 1 1 1 0 Rabosyn-5 repeating NPF sequence-motif IMS PF00817.20 CDJ95105.1 - 1e-38 132.7 0.1 3.6e-38 130.9 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family BRCT_2 PF16589.5 CDJ95105.1 - 4.3e-13 49.5 0.0 9.2e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain IMS_C PF11799.8 CDJ95105.1 - 2.5e-12 47.5 0.0 6.3e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT PF00533.26 CDJ95105.1 - 7.3e-09 35.9 0.0 1.6e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF1805 PF08827.11 CDJ95105.1 - 0.0027 18.0 0.0 0.0084 16.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1805) LIG3_BRCT PF16759.5 CDJ95105.1 - 0.0057 16.9 0.0 0.035 14.4 0.0 2.1 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain UPF0020 PF01170.18 CDJ95105.1 - 0.093 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PTCB-BRCT PF12738.7 CDJ95105.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain DUF3573 PF12097.8 CDJ95106.1 - 0.029 13.2 0.2 0.036 12.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) WD40 PF00400.32 CDJ95107.1 - 9e-07 29.5 4.8 0.0056 17.5 0.4 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF148 PF02520.17 CDJ95109.1 - 5.1e-21 74.8 3.3 6.5e-21 74.5 3.3 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 KxDL PF10241.9 CDJ95109.1 - 0.013 15.8 0.6 0.013 15.8 0.6 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein NB-ARC PF00931.22 CDJ95109.1 - 0.038 13.2 0.1 0.047 12.9 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain Baculo_PEP_C PF04513.12 CDJ95109.1 - 0.06 13.4 0.1 0.078 13.0 0.1 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliJ PF02050.16 CDJ95109.1 - 0.32 11.2 4.1 1.8 8.8 1.5 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein DAO PF01266.24 CDJ95110.1 - 9.6e-19 68.2 0.0 1.1e-18 68.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDJ95110.1 - 6.5e-07 29.5 0.0 1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CDJ95110.1 - 0.00023 20.4 0.0 0.00029 20.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 CDJ95110.1 - 0.012 14.9 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 CDJ95110.1 - 0.013 14.9 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 GMC oxidoreductase Pyr_redox_2 PF07992.14 CDJ95110.1 - 0.016 14.4 0.0 0.018 14.3 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDJ95110.1 - 0.12 11.6 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Thi4 family Recep_L_domain PF01030.24 CDJ95111.1 - 2.6e-48 162.8 1.9 1.5e-25 89.5 0.6 2.5 2 0 0 2 2 2 2 Receptor L domain Furin-like PF00757.20 CDJ95111.1 - 6.8e-24 84.4 34.3 1.2e-23 83.6 34.3 1.4 1 0 0 1 1 1 1 Furin-like cysteine rich region GF_recep_IV PF14843.6 CDJ95111.1 - 2 8.2 39.3 0.15 11.9 18.0 3.3 1 1 2 3 3 3 0 Growth factor receptor domain IV fn3 PF00041.21 CDJ95113.1 - 7.6e-06 26.2 5.0 0.00036 20.8 0.2 3.3 3 1 0 3 3 3 2 Fibronectin type III domain DUF2300 PF10062.9 CDJ95113.1 - 0.04 14.0 0.0 2.9 8.0 0.0 2.5 2 0 0 2 2 2 0 Predicted secreted protein (DUF2300) GDPD PF03009.17 CDJ95114.1 - 7.9e-72 242.1 0.2 1.1e-71 241.6 0.2 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CBM_20 PF00686.19 CDJ95114.1 - 1.7e-06 27.9 0.0 5.9e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Starch binding domain WTF PF03303.13 CDJ95114.1 - 0.036 13.8 0.0 0.058 13.1 0.0 1.2 1 0 0 1 1 1 0 WTF protein EGF_2 PF07974.13 CDJ95115.1 - 5.2e-10 39.5 45.0 0.0063 16.9 2.4 5.7 5 0 0 5 5 5 5 EGF-like domain Laminin_EGF PF00053.24 CDJ95115.1 - 1.4e-06 28.4 51.3 0.00052 20.1 7.1 5.7 2 1 4 6 6 6 5 Laminin EGF domain EGF_Tenascin PF18720.1 CDJ95115.1 - 0.028 14.5 0.8 0.028 14.5 0.8 5.6 5 1 1 6 6 6 0 Tenascin EGF domain hEGF PF12661.7 CDJ95115.1 - 5.9 7.7 52.3 0.27 11.9 3.1 6.8 7 0 0 7 7 7 0 Human growth factor-like EGF Myosin_head PF00063.21 CDJ95117.1 - 1.1e-254 846.8 7.7 1.8e-249 829.5 0.2 3.8 2 1 1 3 3 3 2 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CDJ95117.1 - 9.7e-216 719.0 275.4 1.2e-215 718.8 275.4 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 CDJ95117.1 - 0.0012 18.6 0.0 0.0029 17.4 0.0 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Tropomyosin_1 PF12718.7 CDJ95117.1 - 0.006 16.8 21.4 0.006 16.8 21.4 12.7 1 1 9 11 11 11 2 Tropomyosin like AAA_22 PF13401.6 CDJ95117.1 - 0.053 13.8 0.0 0.053 13.8 0.0 5.1 4 2 0 4 4 4 0 AAA domain CSD PF00313.22 CDJ95118.1 - 6.2e-27 93.2 0.4 1e-26 92.6 0.4 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain FXMRP1_C_core PF12235.8 CDJ95118.1 - 1.6 9.4 24.2 0.063 13.9 14.0 2.3 1 1 1 2 2 2 0 Fragile X-related 1 protein core C terminal Glyco_transf_41 PF13844.6 CDJ95119.1 - 6e-256 849.3 0.1 7.8e-256 848.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 41 TPR_1 PF00515.28 CDJ95119.1 - 4.5e-84 273.1 33.2 2.6e-08 33.3 0.0 12.4 12 0 0 12 12 12 11 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ95119.1 - 5.7e-80 262.8 37.8 9.4e-12 44.4 0.5 12.2 2 2 10 12 12 12 12 TPR repeat TPR_2 PF07719.17 CDJ95119.1 - 1.6e-62 202.6 29.5 1.5e-06 27.9 0.1 11.7 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ95119.1 - 1.2e-56 184.2 22.1 8.5e-06 25.6 0.0 11.7 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ95119.1 - 1.7e-54 178.4 38.8 2e-06 27.8 0.3 12.9 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ95119.1 - 6.1e-37 125.8 30.6 6.5e-11 42.4 3.1 8.5 4 2 4 8 8 7 7 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ95119.1 - 9.1e-36 122.2 16.4 3.4e-08 34.0 0.2 6.9 5 1 2 7 7 7 7 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ95119.1 - 1.7e-30 103.1 16.1 0.024 15.4 0.1 11.3 4 3 7 11 11 11 7 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ95119.1 - 3.9e-30 101.6 14.7 0.0027 17.6 0.0 11.5 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ95119.1 - 1.3e-29 102.5 29.0 1e-06 29.1 0.1 7.3 3 2 3 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ95119.1 - 2.4e-27 94.0 44.9 3.5e-06 26.7 0.4 11.3 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ95119.1 - 1.6e-12 47.4 8.0 0.0064 16.6 0.3 5.9 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_4 PF07721.14 CDJ95119.1 - 9.2e-10 38.2 3.2 0.25 12.1 1.0 7.8 8 0 0 8 8 7 1 Tetratricopeptide repeat NARP1 PF12569.8 CDJ95119.1 - 1.8e-09 37.1 4.4 0.012 14.6 0.1 5.1 2 1 3 6 6 6 3 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 CDJ95119.1 - 2.1e-09 37.4 21.8 0.29 11.8 0.0 9.2 10 0 0 10 10 8 2 Tetratricopeptide repeat FAT PF02259.23 CDJ95119.1 - 1.2e-06 28.0 1.2 0.18 11.0 0.2 5.9 3 2 2 6 6 6 2 FAT domain TPR_MalT PF17874.1 CDJ95119.1 - 1.3e-06 28.1 15.6 0.0058 16.1 0.3 4.6 2 1 1 4 4 4 3 MalT-like TPR region TPR_15 PF13429.6 CDJ95119.1 - 5.1e-05 22.6 6.7 0.29 10.3 1.0 3.7 1 1 0 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.12 CDJ95119.1 - 9.4e-05 22.3 7.5 0.76 9.8 0.0 6.2 8 0 0 8 8 6 2 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 CDJ95119.1 - 0.00011 21.9 11.6 0.012 15.1 0.1 3.7 4 0 0 4 4 4 2 Est1 DNA/RNA binding domain BTAD PF03704.17 CDJ95119.1 - 0.0088 16.5 7.3 0.51 10.8 0.3 4.1 3 1 0 3 3 3 1 Bacterial transcriptional activator domain TOM20_plant PF06552.12 CDJ95119.1 - 0.062 13.0 0.5 5.6 6.7 0.1 3.3 2 2 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_21 PF09976.9 CDJ95119.1 - 0.11 12.2 14.4 2.6 7.7 2.0 5.1 2 2 2 4 4 4 0 Tetratricopeptide repeat-like domain Sec16_C PF12931.7 CDJ95119.1 - 0.13 11.9 1.8 2.1 7.9 0.0 3.1 2 1 1 3 3 3 0 Sec23-binding domain of Sec16 Wzy_C_2 PF11846.8 CDJ95119.1 - 0.21 11.5 5.5 2 8.3 0.6 3.8 3 1 1 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal Mad3_BUB1_I PF08311.12 CDJ95119.1 - 0.38 10.8 12.2 49 3.9 0.2 6.3 5 1 1 6 6 6 0 Mad3/BUB1 homology region 1 SHNi-TPR PF10516.9 CDJ95119.1 - 0.56 9.7 8.2 29 4.2 0.0 5.8 7 1 1 8 8 8 0 SHNi-TPR MIT PF04212.18 CDJ95119.1 - 0.78 9.9 23.8 13 6.0 0.3 8.4 9 1 1 10 10 9 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 CDJ95119.1 - 2.7 8.4 12.3 35 4.8 0.0 5.3 4 1 2 6 6 6 0 Tetratricopeptide repeat DUF357 PF04010.13 CDJ95119.1 - 8.6 6.5 8.4 5.1 7.2 0.2 3.9 4 0 0 4 4 3 0 Protein of unknown function (DUF357) ANAPC3 PF12895.7 CDJ95119.1 - 9 6.6 19.6 0.8 10.0 2.2 3.9 3 1 2 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 POT1PC PF16686.5 CDJ95120.1 - 6.1e-07 29.4 0.0 8.7e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 ssDNA-binding domain of telomere protection protein Phage_coat PF09063.10 CDJ95120.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Phage PP7 coat protein EAL PF00563.20 CDJ95121.1 - 0.09 12.3 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 EAL domain Actin PF00022.19 CDJ95122.1 - 2.3e-120 401.9 0.0 1e-119 399.8 0.0 1.8 1 1 0 1 1 1 1 Actin CLN3 PF02487.17 CDJ95123.1 - 9.8e-120 400.2 6.5 1.2e-119 400.0 6.5 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 CDJ95123.1 - 0.013 14.4 23.3 0.056 12.4 2.4 3.1 2 1 1 3 3 3 0 Major Facilitator Superfamily RseC_MucC PF04246.12 CDJ95123.1 - 1.6 8.7 0.0 1.6 8.7 0.0 3.1 3 1 1 4 4 4 0 Positive regulator of sigma(E), RseC/MucC CBM_14 PF01607.24 CDJ95124.1 - 7.7e-41 138.1 140.4 5e-13 49.0 2.7 14.1 7 4 7 14 14 14 12 Chitin binding Peritrophin-A domain CBM_19 PF03427.13 CDJ95124.1 - 0.033 14.2 54.5 0.21 11.6 0.3 9.4 8 1 1 9 9 9 0 Carbohydrate binding domain (family 19) START PF01852.19 CDJ95125.1 - 1.2e-29 103.3 0.0 1.5e-29 103.0 0.0 1.0 1 0 0 1 1 1 1 START domain DSPc PF00782.20 CDJ95127.1 - 2.9e-38 130.7 0.0 4.3e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 CDJ95127.1 - 0.00097 19.4 0.1 0.0028 18.0 0.0 1.7 2 0 0 2 2 2 1 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 CDJ95127.1 - 0.0011 19.1 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 CDJ95127.1 - 0.016 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ion_trans_2 PF07885.16 CDJ95128.1 - 1.9e-34 117.5 18.0 1.3e-17 63.5 10.5 3.0 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CDJ95128.1 - 1.8e-08 33.9 5.6 9.8e-05 21.7 0.0 2.5 2 1 0 2 2 2 2 Ion transport protein Lig_chan PF00060.26 CDJ95128.1 - 0.043 13.7 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Ligand-gated ion channel Acetyltransf_16 PF05301.11 CDJ95130.1 - 1.3e-55 187.9 0.0 1.8e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_10 PF13673.7 CDJ95130.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PUF PF00806.19 CDJ95131.1 - 1.6e-51 169.2 5.8 7e-08 31.7 0.0 6.5 6 0 0 6 6 6 6 Pumilio-family RNA binding repeat GST_N_3 PF13417.6 CDJ95131.1 - 2.8e-12 46.9 0.1 1e-11 45.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 CDJ95131.1 - 2.3e-07 30.9 0.4 6.5e-07 29.5 0.4 1.8 1 0 0 1 1 1 1 Glutaredoxin GST_N PF02798.20 CDJ95131.1 - 6.3e-06 26.4 0.0 5.6e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 CDJ95131.1 - 0.00045 20.9 0.8 0.0096 16.7 0.0 3.4 4 0 0 4 4 4 1 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.6 CDJ95131.1 - 0.0014 18.9 0.0 0.0039 17.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PLN_propep PF16485.5 CDJ95131.1 - 0.048 13.4 0.2 2.3 8.0 0.1 2.7 2 0 0 2 2 2 0 Protealysin propeptide GST_C PF00043.25 CDJ95131.1 - 0.1 12.8 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain sCache_2 PF17200.4 CDJ95131.1 - 0.11 12.3 0.0 2.2 8.1 0.0 2.7 3 0 0 3 3 3 0 Single Cache domain 2 Wza_C PF18412.1 CDJ95133.1 - 0.017 14.9 0.0 32 4.4 0.0 3.7 4 0 0 4 4 4 0 Outer-membrane lipoprotein Wza C-terminal domain DUF4314 PF14192.6 CDJ95133.1 - 2.2 8.3 7.2 50 3.9 3.7 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4314) Nic96 PF04097.14 CDJ95134.1 - 1.7e-38 132.5 0.0 2.2e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Copine PF07002.16 CDJ95135.1 - 1.8e-12 47.2 0.0 2.3e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Copine Patched PF02460.18 CDJ95137.1 - 1.1e-237 791.1 18.0 3.9e-234 779.4 17.9 2.0 1 1 1 2 2 2 2 Patched family Sterol-sensing PF12349.8 CDJ95137.1 - 1.1e-30 106.4 2.6 1.1e-30 106.4 2.6 3.1 3 1 1 4 4 4 2 Sterol-sensing domain of SREBP cleavage-activation Pam17 PF08566.10 CDJ95137.1 - 0.6 9.9 3.4 0.68 9.8 0.2 2.6 3 0 0 3 3 3 0 Mitochondrial import protein Pam17 DUF5354 PF17305.2 CDJ95139.1 - 0.062 13.5 0.4 0.062 13.5 0.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5354) AcetylCoA_hyd_C PF13336.6 CDJ95140.1 - 3.8e-60 202.3 0.0 5.8e-60 201.7 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 CDJ95140.1 - 3.8e-21 76.0 0.0 1.4e-20 74.1 0.0 1.8 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 CDJ95141.1 - 2e-59 199.9 0.0 3.2e-59 199.3 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 CDJ95141.1 - 2.8e-17 63.3 0.0 1.1e-16 61.5 0.0 1.8 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 CDJ95142.1 - 4.4e-61 205.3 0.0 1.3e-60 203.8 0.0 1.8 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 CDJ95142.1 - 2.8e-17 63.3 0.0 1.6e-16 60.9 0.0 2.0 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase N-terminal domain PKcGMP_CC PF16808.5 CDJ95143.1 - 0.013 15.3 4.9 0.013 15.3 4.9 6.1 4 2 1 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF5082 PF16888.5 CDJ95143.1 - 6.4 7.1 50.9 0.13 12.6 5.9 5.4 2 2 1 4 4 4 0 Domain of unknown function (DUF5082) CPL PF08144.11 CDJ95144.1 - 2.5e-30 105.7 1.7 5.4e-28 98.1 0.0 4.3 5 0 0 5 5 5 1 CPL (NUC119) domain AcetylCoA_hyd_C PF13336.6 CDJ95145.1 - 3.3e-60 202.5 0.0 1e-59 200.9 0.0 1.8 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 CDJ95145.1 - 1.5e-17 64.2 0.0 3.8e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain Motile_Sperm PF00635.26 CDJ95145.1 - 0.073 12.9 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 MSP (Major sperm protein) domain TIL PF01826.17 CDJ95146.1 - 4.6e-17 62.0 38.4 4.7e-11 42.8 16.7 6.0 6 0 0 6 6 6 2 Trypsin Inhibitor like cysteine rich domain Thyroglobulin_1 PF00086.18 CDJ95146.1 - 3.3e-10 39.5 1.6 3.3e-10 39.5 1.6 2.5 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat WAP PF00095.21 CDJ95146.1 - 8.7e-06 26.0 10.6 8.7e-06 26.0 10.6 7.5 7 2 0 7 7 7 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' Peptidase_C1 PF00112.23 CDJ95148.1 - 4.6e-41 141.3 4.8 5.6e-41 141.0 4.8 1.1 1 0 0 1 1 1 1 Papain family cysteine protease FixQ PF05545.11 CDJ95148.1 - 0.083 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ p450 PF00067.22 CDJ95149.1 - 2.3e-27 95.9 0.0 2.8e-27 95.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CRAL_TRIO PF00650.20 CDJ95151.1 - 1.2e-22 80.4 0.0 2e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain DUF5620 PF18522.1 CDJ95151.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5620) Hydrolase_6 PF13344.6 CDJ95152.1 - 8.7e-18 64.3 0.0 2.7e-17 62.7 0.0 1.9 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDJ95152.1 - 1.9e-08 34.9 0.1 0.0012 19.2 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CDJ95152.1 - 1.3e-07 31.5 0.0 2.6e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like DUF1912 PF08930.10 CDJ95153.1 - 0.13 12.5 0.1 0.19 11.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) Hydrolase_6 PF13344.6 CDJ95155.1 - 2.5e-52 175.2 0.0 3.2e-25 88.2 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CDJ95155.1 - 9.6e-36 121.7 0.0 1.2e-16 60.5 0.0 2.7 2 0 0 2 2 2 2 HAD-hyrolase-like Hydrolase PF00702.26 CDJ95155.1 - 5.4e-28 98.7 0.0 1.7e-13 51.4 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CDJ95155.1 - 6.2e-12 45.9 0.0 0.00031 20.9 0.0 3.6 4 0 0 4 4 4 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 CDJ95155.1 - 5.6e-05 22.8 0.0 0.46 10.1 0.0 2.8 2 0 0 2 2 2 2 Mitochondrial PGP phosphatase Asp_Glu_race PF01177.22 CDJ95155.1 - 0.00085 19.2 0.0 1.6 8.5 0.0 2.6 2 0 0 2 2 2 2 Asp/Glu/Hydantoin racemase S6PP PF05116.13 CDJ95155.1 - 0.0028 17.2 0.0 2.4 7.6 0.0 2.5 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Acid_phosphat_B PF03767.14 CDJ95155.1 - 0.022 14.3 0.0 5.2 6.6 0.0 2.3 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Reg_prop PF07494.11 CDJ95155.1 - 0.039 14.2 1.5 16 6.1 0.1 2.9 2 0 0 2 2 2 0 Two component regulator propeller DUF2608 PF11019.8 CDJ95155.1 - 0.069 12.6 0.0 4 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) Exo84_C PF16528.5 CDJ95155.1 - 0.14 11.9 0.1 3.6 7.4 0.0 2.1 2 0 0 2 2 2 0 Exocyst component 84 C-terminal LEM PF03020.15 CDJ95155.1 - 0.24 11.0 3.7 11 5.7 0.1 2.8 3 0 0 3 3 3 0 LEM domain Hydrolase_6 PF13344.6 CDJ95156.1 - 2.3e-24 85.4 0.0 4e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CDJ95156.1 - 1.3e-17 63.6 0.0 2.8e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CDJ95156.1 - 8.2e-13 49.1 0.0 1.1e-12 48.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CDJ95156.1 - 7.4e-05 22.9 0.0 0.00023 21.3 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase zf-C2H2_4 PF13894.6 CDJ95157.1 - 3.3e-10 39.9 23.8 0.00094 19.8 0.9 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 CDJ95157.1 - 5.5e-08 32.8 25.1 0.00053 20.3 1.1 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ95157.1 - 1.8e-06 28.1 18.7 0.0087 16.5 0.1 5.6 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CDJ95157.1 - 0.0044 17.3 9.0 0.021 15.1 0.4 3.2 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 CDJ95157.1 - 0.013 16.1 5.9 0.039 14.6 0.1 3.4 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 CDJ95157.1 - 0.039 14.3 6.1 0.84 10.1 0.4 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CDJ95157.1 - 0.069 13.2 0.8 0.069 13.2 0.8 4.6 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CDJ95157.1 - 0.095 13.1 4.3 4.3 7.7 0.0 3.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) CpXC PF14353.6 CDJ95157.1 - 0.31 11.1 8.4 6 6.9 0.4 4.0 2 1 2 4 4 4 0 CpXC protein zf_UBZ PF18439.1 CDJ95157.1 - 0.41 10.3 4.3 10 5.8 0.1 3.0 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-BED PF02892.15 CDJ95157.1 - 1.1 9.4 7.7 8 6.6 0.1 3.3 2 1 1 3 3 3 0 BED zinc finger zf-C2HE PF16278.5 CDJ95157.1 - 2.9 8.4 9.4 20 5.7 0.2 3.7 2 2 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Ldh_1_N PF00056.23 CDJ95158.1 - 3.4e-34 118.0 0.1 5.7e-34 117.2 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CDJ95158.1 - 3.9e-33 114.7 0.0 8.3e-33 113.7 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain EHN PF06441.12 CDJ95159.1 - 1.9e-31 108.6 1.1 3.4e-31 107.8 1.1 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 CDJ95159.1 - 5.7e-17 62.2 0.0 1e-16 61.4 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ95159.1 - 0.0013 19.4 0.0 0.0026 18.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Imm41 PF15592.6 CDJ95159.1 - 0.014 15.7 0.7 0.033 14.5 0.7 1.6 1 0 0 1 1 1 0 Immunity protein 41 Transgly_assoc PF04226.13 CDJ95159.1 - 0.083 13.2 0.0 3.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Transglycosylase associated protein Carn_acyltransf PF00755.20 CDJ95160.1 - 3.1e-32 112.0 0.0 3.3e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase FAIM1 PF06905.13 CDJ95161.1 - 1.7e-82 275.3 1.6 1.9e-82 275.2 1.6 1.0 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) Pkinase PF00069.25 CDJ95162.1 - 2.2e-71 240.3 0.0 2.7e-71 240.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ95162.1 - 4e-39 134.4 0.0 5.5e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ95162.1 - 1.5e-05 24.4 0.0 3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CDJ95162.1 - 0.015 14.1 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CDJ95162.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family P3A PF08727.11 CDJ95163.1 - 0.034 13.5 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Poliovirus 3A protein like DAGAT PF03982.13 CDJ95164.1 - 1.3e-122 408.3 0.0 1.8e-122 407.9 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF3136 PF11334.8 CDJ95164.1 - 0.039 13.7 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) Branch PF02485.21 CDJ95165.1 - 3.4e-31 108.6 0.0 6.3e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 Core-2/I-Branching enzyme WSC PF01822.19 CDJ95165.1 - 9.4e-15 54.6 9.1 9.4e-15 54.6 9.1 2.0 2 0 0 2 2 2 1 WSC domain Cyclin_N PF00134.23 CDJ95165.1 - 1.2e-12 47.7 0.0 1.2e-11 44.4 0.0 2.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain Xylo_C PF12529.8 CDJ95165.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Xylosyltransferase C terminal PCO_ADO PF07847.12 CDJ95166.1 - 1.8e-24 86.3 0.0 2.3e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 PCO_ADO CDO_I PF05995.12 CDJ95166.1 - 0.057 12.7 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 Cysteine dioxygenase type I Lustrin_cystein PF14625.6 CDJ95166.1 - 0.99 9.8 5.2 0.13 12.6 1.0 1.7 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain RMI1_N PF08585.12 CDJ95167.1 - 1.2e-20 74.3 6.3 8.6e-18 64.9 0.0 3.3 2 1 1 3 3 3 2 RecQ mediated genome instability protein Tudor_2 PF18104.1 CDJ95167.1 - 6.9e-05 22.4 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain TUDOR PF00567.24 CDJ95167.1 - 0.033 14.2 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Tudor domain GREB1 PF15782.5 CDJ95167.1 - 7 3.6 12.4 9.9 3.1 12.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Fe-S_biosyn PF01521.20 CDJ95168.1 - 1.1e-19 70.6 0.0 1.3e-19 70.4 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Acetyltransf_1 PF00583.25 CDJ95169.1 - 2.2e-13 50.5 0.0 2.7e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDJ95169.1 - 1.6e-08 34.5 0.0 2.3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CDJ95169.1 - 6.6e-07 29.6 0.2 1e-06 29.0 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDJ95169.1 - 7.6e-07 29.5 0.2 1.1e-06 28.9 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDJ95169.1 - 3.4e-06 26.9 0.0 7.4e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 CDJ95169.1 - 1.2e-05 26.1 0.1 1.5e-05 25.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CDJ95169.1 - 0.0014 18.7 0.1 0.0022 18.1 0.1 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Ca_bind_SSO6904 PF18249.1 CDJ95169.1 - 0.032 14.6 0.0 0.055 13.8 0.0 1.3 1 0 0 1 1 1 0 Calcium binding protein SSO6904 Y_phosphatase PF00102.27 CDJ95170.1 - 3.7e-64 216.5 0.0 4.7e-64 216.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ95170.1 - 0.00015 21.6 0.2 0.00048 19.9 0.1 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain HJURP_mid PF12346.8 CDJ95170.1 - 0.0081 16.6 0.1 0.016 15.7 0.1 1.5 1 0 0 1 1 1 1 Holliday junction recognition protein-associated repeat Y_phosphatase3 PF13350.6 CDJ95170.1 - 0.091 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Methyltransf_PK PF05891.12 CDJ95170.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Mucin PF01456.17 CDJ95171.1 - 2 8.4 16.1 0.07 13.1 6.6 2.6 2 0 0 2 2 2 0 Mucin-like glycoprotein Malate_synthase PF01274.22 CDJ95172.1 - 9.9e-198 657.6 0.0 1.3e-197 657.2 0.0 1.1 1 0 0 1 1 1 1 Malate synthase ICL PF00463.21 CDJ95172.1 - 8.1e-108 361.2 1.2 1.5e-54 185.4 0.4 2.6 2 1 1 3 3 3 2 Isocitrate lyase family PEP_mutase PF13714.6 CDJ95172.1 - 7.8e-13 48.4 0.1 1.4e-12 47.6 0.1 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase HpcH_HpaI PF03328.14 CDJ95172.1 - 0.015 14.4 0.0 0.08 12.1 0.0 2.1 2 0 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family ASPRs PF17641.2 CDJ95173.1 - 0.00046 20.5 0.2 0.00052 20.3 0.2 1.1 1 0 0 1 1 1 1 Ancylostoma-associated secreted protein related ApoC-I PF04691.12 CDJ95173.1 - 0.038 13.9 1.5 0.099 12.6 1.1 1.8 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) ASPRs PF17641.2 CDJ95174.1 - 0.00026 21.3 0.4 0.0003 21.0 0.4 1.1 1 0 0 1 1 1 1 Ancylostoma-associated secreted protein related ApoC-I PF04691.12 CDJ95174.1 - 0.074 13.0 1.4 0.15 12.0 0.6 1.8 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) DUF2471 PF10616.9 CDJ95175.1 - 0.019 15.5 0.1 0.029 14.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2471) ASPRs PF17641.2 CDJ95176.1 - 0.00015 22.1 0.2 0.00017 21.9 0.2 1.1 1 0 0 1 1 1 1 Ancylostoma-associated secreted protein related ApoC-I PF04691.12 CDJ95176.1 - 0.036 14.0 1.5 0.099 12.6 1.1 1.8 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) ASPRs PF17641.2 CDJ95177.1 - 0.001 19.4 0.2 0.0012 19.2 0.2 1.1 1 0 0 1 1 1 1 Ancylostoma-associated secreted protein related ApoC-I PF04691.12 CDJ95177.1 - 0.077 12.9 1.8 0.13 12.2 0.5 2.0 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) TPR_20 PF14561.6 CDJ95177.1 - 0.099 13.0 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat AAA PF00004.29 CDJ95179.1 - 1.7e-38 132.0 0.0 3.3e-38 131.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ95179.1 - 2.5e-10 40.0 0.0 6.3e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CDJ95179.1 - 5.3e-06 26.7 0.1 2.4e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CDJ95179.1 - 8.1e-06 25.9 0.4 0.00016 21.7 0.1 3.2 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CDJ95179.1 - 1.9e-05 24.5 0.0 3.9e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CDJ95179.1 - 0.00034 20.9 0.1 0.0097 16.2 0.1 2.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CDJ95179.1 - 0.00087 19.1 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TniB PF05621.11 CDJ95179.1 - 0.0011 18.5 0.0 0.7 9.3 0.0 2.6 1 1 1 2 2 2 2 Bacterial TniB protein AAA_16 PF13191.6 CDJ95179.1 - 0.0014 19.1 0.5 0.24 11.7 0.0 2.8 1 1 2 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.21 CDJ95179.1 - 0.0024 17.3 0.3 0.0088 15.4 0.3 1.9 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CDJ95179.1 - 0.0028 17.7 0.0 0.007 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CDJ95179.1 - 0.0032 18.0 0.0 0.011 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 CDJ95179.1 - 0.0044 16.2 0.0 0.0085 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 CDJ95179.1 - 0.0075 16.1 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial dnaA protein TIP49 PF06068.13 CDJ95179.1 - 0.0088 15.3 0.2 0.02 14.1 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_24 PF13479.6 CDJ95179.1 - 0.016 14.9 0.0 0.073 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CDJ95179.1 - 0.017 15.0 0.1 0.1 12.5 0.0 2.1 1 1 1 2 2 2 0 NACHT domain RNA_helicase PF00910.22 CDJ95179.1 - 0.024 15.0 0.1 0.16 12.4 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_29 PF13555.6 CDJ95179.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 CDJ95179.1 - 0.089 13.0 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Vps4_C PF09336.10 CDJ95179.1 - 0.095 12.7 0.0 0.54 10.3 0.0 2.1 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Sigma54_activat PF00158.26 CDJ95179.1 - 0.18 11.5 0.0 2.1 8.0 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 CDJ95179.1 - 0.39 10.6 2.1 8.8 6.2 0.0 2.8 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Lig_chan-Glu_bd PF10613.9 CDJ95180.1 - 8.1e-28 96.9 0.0 6.1e-27 94.1 0.0 2.2 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 CDJ95180.1 - 6.5e-26 91.0 0.2 1.2e-25 90.1 0.2 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 CDJ95180.1 - 4.9e-23 81.8 0.0 1.1e-22 80.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 CDJ95180.1 - 1.7e-17 63.6 0.4 5.9e-17 61.8 0.2 2.0 2 1 0 2 2 2 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 CDJ95180.1 - 0.025 14.3 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Ribophorin_I PF04597.14 CDJ95181.1 - 3.5e-133 445.0 5.2 4.4e-133 444.7 5.2 1.1 1 0 0 1 1 1 1 Ribophorin I RPN1_RPN2_N PF17781.1 CDJ95183.1 - 2.3e-42 145.5 1.5 2.6e-32 112.4 0.7 2.6 1 1 1 2 2 2 2 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 CDJ95183.1 - 2.1e-31 107.7 0.1 3.7e-31 106.9 0.1 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 CDJ95183.1 - 5.7e-15 54.9 15.4 0.00018 21.8 0.1 8.0 8 0 0 8 8 8 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CDJ95183.1 - 0.00038 20.8 0.2 1.4 9.3 0.0 3.8 2 1 1 3 3 3 1 HEAT repeats DYW_deaminase PF14432.6 CDJ95183.1 - 0.018 14.9 0.5 0.046 13.6 0.5 1.7 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases THAP PF05485.12 CDJ95183.1 - 0.14 13.1 0.3 0.4 11.6 0.3 1.7 1 0 0 1 1 1 0 THAP domain Cytomega_UL84 PF06284.11 CDJ95183.1 - 0.99 7.8 4.6 7.9 4.8 4.4 2.0 2 0 0 2 2 2 0 Cytomegalovirus UL84 protein PPL5 PF18168.1 CDJ95183.1 - 2.1 7.6 13.6 4.6 6.4 6.6 2.2 2 0 0 2 2 2 0 Prim-pol family 5 DUF3464 PF11947.8 CDJ95183.1 - 3.8 7.2 10.6 4.4 7.0 0.0 2.7 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 EGF PF00008.27 CDJ95184.1 - 1e-57 192.0 159.2 3.8e-08 33.5 6.2 13.9 12 0 0 12 12 12 11 EGF-like domain Ephrin_rec_like PF07699.13 CDJ95184.1 - 1.5e-37 127.1 63.9 1.1e-11 44.3 8.0 7.4 5 1 1 6 6 6 4 Putative ephrin-receptor like hEGF PF12661.7 CDJ95184.1 - 4.5e-34 115.9 140.0 1.2e-05 25.7 6.5 15.0 13 1 1 14 14 14 10 Human growth factor-like EGF EGF_2 PF07974.13 CDJ95184.1 - 1.9e-13 50.5 183.9 0.0099 16.2 12.7 14.0 11 2 2 13 13 13 11 EGF-like domain Laminin_G_3 PF13385.6 CDJ95184.1 - 9.6e-12 45.3 0.8 1.7e-11 44.5 0.8 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF_3 PF12947.7 CDJ95184.1 - 2.1e-10 40.6 33.9 3.4e-08 33.5 7.7 13.6 10 3 2 12 12 12 6 EGF domain HYR PF02494.16 CDJ95184.1 - 4.1e-09 36.6 0.2 1.4e-08 35.0 0.2 1.9 1 0 0 1 1 1 1 HYR domain EGF_CA PF07645.15 CDJ95184.1 - 0.00015 21.9 37.9 0.0014 18.7 5.7 16.7 7 4 10 17 17 17 7 Calcium-binding EGF domain Pentaxin PF00354.17 CDJ95184.1 - 0.00027 20.7 0.1 0.0084 15.8 0.0 2.2 2 0 0 2 2 2 1 Pentaxin family cEGF PF12662.7 CDJ95184.1 - 0.0015 18.4 4.9 0.0015 18.4 4.9 15.3 17 2 1 18 18 18 5 Complement Clr-like EGF-like Claudin_2 PF13903.6 CDJ95185.1 - 1.1 8.9 10.8 1.9 8.2 10.6 1.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Sushi PF00084.20 CDJ95186.1 - 5.2e-51 171.1 47.6 7e-10 39.4 0.5 10.6 11 0 0 11 11 10 8 Sushi repeat (SCR repeat) EGF PF00008.27 CDJ95186.1 - 1.1e-19 70.3 70.8 1.1e-06 28.8 6.6 8.9 8 0 0 8 8 8 5 EGF-like domain Lectin_C PF00059.21 CDJ95186.1 - 7.5e-19 68.5 0.1 3.5e-18 66.3 0.1 2.3 1 0 0 1 1 1 1 Lectin C-type domain HYR PF02494.16 CDJ95186.1 - 2.4e-18 66.2 3.3 4.4e-08 33.3 0.7 2.8 2 0 0 2 2 2 2 HYR domain Ephrin_rec_like PF07699.13 CDJ95186.1 - 1e-13 50.8 31.3 4.8e-12 45.4 5.9 5.8 2 2 1 3 3 3 2 Putative ephrin-receptor like CUB PF00431.20 CDJ95186.1 - 6.3e-13 49.0 0.0 1.3e-06 28.7 0.0 2.6 2 0 0 2 2 2 2 CUB domain EGF_CA PF07645.15 CDJ95186.1 - 7e-13 48.5 12.4 3.7e-08 33.4 6.7 10.4 9 3 2 11 11 9 5 Calcium-binding EGF domain F5_F8_type_C PF00754.25 CDJ95186.1 - 4e-10 39.9 0.0 1.1e-09 38.5 0.0 1.7 2 0 0 2 2 1 1 F5/8 type C domain hEGF PF12661.7 CDJ95186.1 - 1e-08 35.5 65.7 0.00028 21.4 2.0 10.1 9 0 0 9 9 9 5 Human growth factor-like EGF Ldl_recept_a PF00057.18 CDJ95186.1 - 1.1e-08 35.1 4.9 1.1e-08 35.1 4.9 7.0 6 1 0 6 6 3 1 Low-density lipoprotein receptor domain class A FXa_inhibition PF14670.6 CDJ95186.1 - 1.6e-07 31.5 5.8 1.6e-07 31.5 5.8 10.8 8 1 2 10 10 10 1 Coagulation Factor Xa inhibitory site HRM PF02793.22 CDJ95186.1 - 0.018 15.3 34.0 0.024 14.9 0.2 8.4 8 1 1 9 9 9 0 Hormone receptor domain POT1 PF02765.17 CDJ95187.1 - 0.19 11.6 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 SH3_1 PF00018.28 CDJ95188.1 - 3.6e-67 221.8 8.8 1.1e-15 56.9 0.0 5.4 5 0 0 5 5 5 5 SH3 domain SH3_9 PF14604.6 CDJ95188.1 - 2.8e-64 212.8 3.2 7.7e-15 54.5 0.0 5.4 5 0 0 5 5 5 5 Variant SH3 domain SH3_2 PF07653.17 CDJ95188.1 - 3.7e-59 196.3 0.6 4.3e-13 48.7 0.0 5.5 5 0 0 5 5 5 5 Variant SH3 domain EF-hand_4 PF12763.7 CDJ95188.1 - 1.1e-25 89.6 0.0 4.7e-12 45.8 0.0 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand RhoGEF PF00621.20 CDJ95188.1 - 2.4e-25 89.8 0.0 7.6e-25 88.2 0.0 1.9 1 0 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 CDJ95188.1 - 1e-21 77.3 0.0 1e-21 77.3 0.0 2.5 2 1 1 3 3 1 1 Pleckstrin homology domain EF-hand_1 PF00036.32 CDJ95188.1 - 1.8e-08 33.4 0.0 0.0039 16.7 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDJ95188.1 - 1e-05 25.9 0.0 0.15 12.5 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ95188.1 - 2.2e-05 24.0 0.0 0.17 11.9 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDJ95188.1 - 0.00015 21.1 0.1 0.42 10.2 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDJ95188.1 - 0.069 13.0 0.0 7 6.6 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair Pkinase PF00069.25 CDJ95189.1 - 2.6e-34 118.8 0.0 3e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ95189.1 - 2.8e-11 43.2 0.0 9.3e-11 41.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Peptidase_A17 PF05380.13 CDJ95190.1 - 3.8e-33 114.8 0.0 6.3e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 Pao retrotransposon peptidase Integrase_H2C2 PF17921.1 CDJ95190.1 - 7.9e-11 41.9 0.2 2.5e-10 40.3 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 CDJ95190.1 - 0.0035 17.3 0.0 0.008 16.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ95190.1 - 0.029 14.7 0.0 0.072 13.4 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ95191.1 - 3.4e-12 46.3 0.0 5.7e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CDJ95191.1 - 6.3e-12 45.8 0.0 1.2e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Pao retrotransposon peptidase WW PF00397.26 CDJ95192.1 - 1.1e-06 28.7 1.9 2.8e-06 27.3 1.9 1.8 1 0 0 1 1 1 1 WW domain Neur_chan_memb PF02932.16 CDJ95194.1 - 0.0045 17.1 0.4 0.0048 17.0 0.4 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2678 PF10856.8 CDJ95194.1 - 0.016 15.2 0.4 0.019 14.9 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) VWA PF00092.28 CDJ95195.1 - 1.2e-16 61.4 8.6 3.7e-16 59.9 2.5 2.6 2 1 0 2 2 2 2 von Willebrand factor type A domain Lectin_C PF00059.21 CDJ95195.1 - 3e-13 50.4 0.1 9.3e-13 48.9 0.1 1.9 1 0 0 1 1 1 1 Lectin C-type domain EGF_2 PF07974.13 CDJ95195.1 - 0.00046 20.5 3.0 0.00046 20.5 3.0 3.5 3 0 0 3 3 3 2 EGF-like domain EGF PF00008.27 CDJ95195.1 - 3.4 8.1 11.2 0.25 11.7 1.0 3.0 2 0 0 2 2 2 0 EGF-like domain EGF PF00008.27 CDJ95197.1 - 4.9e-05 23.6 14.6 0.0012 19.1 2.2 4.3 3 1 0 3 3 3 2 EGF-like domain EGF_2 PF07974.13 CDJ95197.1 - 0.07 13.5 21.2 0.11 12.8 2.9 3.1 3 0 0 3 3 3 0 EGF-like domain FXa_inhibition PF14670.6 CDJ95197.1 - 0.54 10.6 8.7 4.4 7.7 1.6 2.9 1 1 1 2 2 2 0 Coagulation Factor Xa inhibitory site Recep_L_domain PF01030.24 CDJ95203.1 - 6.7e-11 42.3 0.5 0.00047 20.2 0.0 3.3 3 0 0 3 3 3 3 Receptor L domain Radical_SAM PF04055.21 CDJ95203.1 - 0.15 12.4 1.5 0.21 12.0 0.1 1.9 2 0 0 2 2 2 0 Radical SAM superfamily PIF1 PF05970.14 CDJ95204.1 - 6.8e-103 344.6 0.0 9e-103 344.2 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 CDJ95204.1 - 7.3e-61 205.7 1.1 1.7e-60 204.5 0.0 2.1 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 CDJ95204.1 - 2e-12 47.3 0.0 5.5e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ95204.1 - 0.0001 22.7 0.0 0.00029 21.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CDJ95204.1 - 0.00021 21.3 0.0 0.00043 20.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 CDJ95204.1 - 0.0015 18.6 0.0 0.014 15.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CDJ95204.1 - 0.002 17.9 0.1 1.4 8.6 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.14 CDJ95204.1 - 0.0037 15.3 0.0 0.0072 14.3 0.0 1.3 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 CDJ95204.1 - 0.032 14.1 0.0 0.088 12.6 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 CDJ95204.1 - 0.62 9.8 0.0 0.62 9.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.7 CDJ95205.1 - 2.2e-50 169.2 0.9 7.6e-18 64.9 0.1 4.3 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ95205.1 - 9.9e-28 96.2 0.4 8.1e-09 35.9 0.0 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 CDJ95205.1 - 4.7e-26 90.1 2.8 0.00017 21.9 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 CDJ95205.1 - 2.4e-25 85.8 7.4 8.6e-05 22.7 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 CDJ95205.1 - 2.8e-25 88.0 5.0 5e-05 23.5 0.1 5.9 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Zip PF02535.22 CDJ95206.1 - 3.2e-56 191.0 38.5 3.2e-54 184.4 6.6 3.0 1 1 2 3 3 3 2 ZIP Zinc transporter Pox_A_type_inc PF04508.12 CDJ95208.1 - 0.0055 16.5 2.6 0.0055 16.5 2.6 8.3 9 0 0 9 9 9 3 Viral A-type inclusion protein repeat Lactamase_B_2 PF12706.7 CDJ95210.1 - 4.7e-39 134.0 0.1 6e-39 133.6 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CDJ95210.1 - 1.7e-13 50.7 0.0 2.5e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 CDJ95211.1 - 6e-40 136.9 0.1 7.5e-40 136.6 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CDJ95211.1 - 1e-14 54.8 0.0 2.5e-14 53.5 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain PP-binding PF00550.25 CDJ95212.1 - 7.3e-13 48.7 0.1 1e-12 48.2 0.1 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 CDJ95212.1 - 0.0077 16.4 0.3 0.011 16.0 0.3 1.3 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_L50 PF10501.9 CDJ95212.1 - 0.017 15.2 0.0 0.029 14.5 0.0 1.4 1 1 0 1 1 1 0 Ribosomal subunit 39S CsgA PF17334.2 CDJ95212.1 - 0.027 15.2 0.0 0.038 14.7 0.0 1.3 1 0 0 1 1 1 0 Minor curli fiber component A tRNA_int_endo PF01974.17 CDJ95213.1 - 1.7e-15 56.8 0.0 4.4e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 CDJ95213.1 - 1.4e-09 37.4 0.0 4e-09 36.0 0.0 1.7 1 1 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Guanylate_cyc PF00211.20 CDJ95215.1 - 1.6e-33 115.9 0.0 2.7e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 CDJ95215.1 - 1.4e-06 27.8 0.0 0.0003 20.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CDJ95215.1 - 5.9e-06 25.8 0.0 0.00018 21.0 0.0 2.3 1 1 1 2 2 2 1 Protein kinase domain HNOBA PF07701.14 CDJ95215.1 - 2.6e-05 23.7 0.4 4e-05 23.2 0.4 1.3 1 0 0 1 1 1 1 Heme NO binding associated dsDNA_bind PF01984.20 CDJ95215.1 - 0.0066 16.7 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF5386 PF17360.2 CDJ95216.1 - 2.6e-13 50.2 1.2 3.4e-08 33.6 0.1 2.2 1 1 1 2 2 2 2 Family of unknown function (DUF5386) HTH_50 PF18024.1 CDJ95217.1 - 0.04 13.5 0.1 0.065 12.9 0.1 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 CDJ95217.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF190 PF02641.15 CDJ95217.1 - 0.11 12.9 0.0 0.13 12.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized ACR, COG1993 CC2D2AN-C2 PF15625.6 CDJ95218.1 - 1.2e-16 60.9 0.0 2e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain DUF883 PF05957.13 CDJ95218.1 - 0.039 14.6 0.5 0.28 11.8 0.3 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) MFS_1 PF07690.16 CDJ95219.1 - 2.3e-07 30.1 0.9 2.8e-07 29.8 0.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2650 PF10853.8 CDJ95220.1 - 1.1e-14 53.8 9.1 1.9e-14 53.1 9.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2650) Peptidase_M10 PF00413.24 CDJ95221.1 - 9.6e-26 90.5 0.0 1.7e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 CDJ95221.1 - 3.4e-20 71.7 3.6 1.7e-10 40.7 0.0 3.6 3 0 0 3 3 3 3 Hemopexin Metallopep PF12044.8 CDJ95221.1 - 0.0016 17.1 0.0 0.0022 16.7 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Peptidase_M66 PF10462.9 CDJ95221.1 - 0.013 14.4 0.1 0.02 13.9 0.1 1.1 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.6 CDJ95221.1 - 0.028 14.9 0.0 0.05 14.1 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 CDJ95221.1 - 0.039 13.6 0.3 0.59 9.7 0.2 2.5 3 0 0 3 3 3 0 Astacin (Peptidase family M12A) Peptidase_M54 PF07998.11 CDJ95221.1 - 0.09 12.8 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M54 DUF4953 PF16313.5 CDJ95221.1 - 0.12 11.6 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Met-zincin BCL_N PF04714.13 CDJ95222.1 - 1e-23 83.1 10.1 1.5e-23 82.6 10.1 1.2 1 0 0 1 1 1 1 BCL7, N-terminal conserver region Mpp10 PF04006.12 CDJ95223.1 - 7.2e-108 361.6 49.8 7.2e-108 361.6 49.8 2.9 3 0 0 3 3 3 1 Mpp10 protein PilJ PF13675.6 CDJ95223.1 - 0.11 12.6 1.7 0.33 11.0 0.5 2.4 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Aminopep PF10023.9 CDJ95224.1 - 1.9 7.8 11.4 3.1 7.1 11.4 1.2 1 0 0 1 1 1 0 Putative aminopeptidase Pox_F15 PF04596.12 CDJ95225.1 - 0.015 15.1 0.0 13 5.6 0.0 3.1 1 1 3 4 4 4 0 Poxvirus protein F15 PUB_1 PF18486.1 CDJ95225.1 - 0.14 12.0 1.2 35 4.4 0.2 3.6 3 1 0 3 3 3 0 PNGase/UBA- or UBX-containing domain Nse4-Nse3_bdg PF15412.6 CDJ95225.1 - 5.4 7.2 8.0 85 3.4 0.1 3.7 4 0 0 4 4 4 0 Binding domain of Nse4/EID3 to Nse3-MAGE ParA PF10609.9 CDJ95226.1 - 7.3e-22 78.0 0.0 8.1e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase TF_Zn_Ribbon PF08271.12 CDJ95226.1 - 0.031 13.8 0.6 0.052 13.1 0.6 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.7 CDJ95226.1 - 0.095 12.7 0.2 0.18 11.8 0.2 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Fer4_NifH PF00142.18 CDJ95226.1 - 0.13 11.6 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ketoacyl-synt PF00109.26 CDJ95227.1 - 5.9e-41 140.7 1.4 3.1e-40 138.4 0.2 2.3 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CDJ95227.1 - 5.3e-36 123.2 0.5 9.2e-36 122.4 0.5 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 CDJ95227.1 - 4.2e-05 24.0 0.0 9.3e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Carb_anhydrase PF00194.21 CDJ95229.1 - 4.2e-49 167.4 0.0 5e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase TMEM100 PF16311.5 CDJ95229.1 - 0.00087 18.9 0.2 0.0017 18.0 0.2 1.4 1 0 0 1 1 1 1 Transmembrane protein 100 YpjP PF14005.6 CDJ95230.1 - 0.52 10.4 1.7 0.95 9.5 0.3 1.8 2 0 0 2 2 2 0 YpjP-like protein PDR_CDR PF06422.12 CDJ95231.1 - 0.057 13.3 0.5 0.096 12.6 0.5 1.4 1 0 0 1 1 1 0 CDR ABC transporter Mucin PF01456.17 CDJ95232.1 - 7 6.6 18.7 1.6e+02 2.3 0.0 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Pkinase PF00069.25 CDJ95233.1 - 1.4e-69 234.5 0.0 1.8e-69 234.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ95233.1 - 8.6e-33 113.7 0.0 1.3e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ95233.1 - 3.2e-06 26.4 0.1 5.5e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CDJ95233.1 - 0.0002 20.8 0.0 0.00032 20.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CDJ95233.1 - 0.0059 16.5 0.4 0.013 15.4 0.5 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CDJ95233.1 - 0.0074 15.4 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 CDJ95233.1 - 0.13 11.6 0.4 0.57 9.5 0.4 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lipase_3 PF01764.25 CDJ95234.1 - 2e-37 128.2 0.0 2.8e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 CDJ95234.1 - 0.00027 20.3 0.0 0.0005 19.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 CDJ95234.1 - 0.0017 17.9 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF2974 PF11187.8 CDJ95234.1 - 0.0089 15.6 0.0 0.19 11.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 CDJ95234.1 - 0.032 13.9 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ95234.1 - 0.039 14.6 0.5 0.18 12.4 0.0 1.9 1 1 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.13 CDJ95234.1 - 0.043 13.5 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_8 PF06259.12 CDJ95234.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase zf-C2H2 PF00096.26 CDJ95235.1 - 2e-13 50.0 36.5 1.7e-06 28.2 1.0 4.2 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ95235.1 - 1.7e-11 44.0 8.1 3.9e-06 27.0 0.6 4.9 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDJ95235.1 - 1.5e-09 37.9 33.6 9.8e-05 22.9 1.1 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger FOXP-CC PF16159.5 CDJ95235.1 - 2.1e-06 28.3 8.1 0.11 13.1 0.9 3.2 2 1 1 3 3 3 3 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 CDJ95235.1 - 0.0026 18.0 1.5 0.19 12.0 0.2 3.7 4 0 0 4 4 3 3 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 CDJ95235.1 - 0.0082 16.1 21.1 0.41 10.7 1.8 3.8 2 2 2 4 4 4 3 BED zinc finger zf-C2H2_aberr PF17017.5 CDJ95235.1 - 0.022 14.9 4.3 1.6 8.8 0.2 2.5 2 1 0 2 2 2 0 Aberrant zinc-finger Ogr_Delta PF04606.12 CDJ95235.1 - 0.027 14.4 2.5 0.027 14.4 2.5 3.9 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger zf-met PF12874.7 CDJ95235.1 - 0.037 14.4 1.7 0.92 10.0 0.1 4.1 5 0 0 5 5 4 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 CDJ95235.1 - 0.2 11.5 0.2 0.2 11.5 0.2 4.5 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 CDJ95235.1 - 0.51 10.4 21.1 0.67 10.0 0.8 3.8 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2HE PF16278.5 CDJ95235.1 - 7.4 7.1 26.1 1.1 9.7 0.5 3.8 3 1 1 4 4 3 0 C2HE / C2H2 / C2HC zinc-binding finger DNA_pol_D_N PF18018.1 CDJ95236.1 - 8.5e-19 67.9 0.5 1.1e-18 67.5 0.5 1.2 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 CDJ95236.1 - 0.0005 19.5 0.0 0.00072 19.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B 7TM_GPCR_Srsx PF10320.9 CDJ95237.1 - 1.9e-06 27.5 2.3 2.1e-06 27.3 2.3 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 CDJ95237.1 - 0.023 14.1 1.9 0.045 13.1 1.9 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv NIF PF03031.18 CDJ95238.1 - 4.1e-51 172.8 0.0 5.5e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase AAA_12 PF13087.6 CDJ95240.1 - 1.1e-33 116.6 0.0 1.7e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ95240.1 - 1.7e-05 24.8 0.0 2.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CDJ95240.1 - 0.00039 20.2 0.1 0.015 15.0 0.0 2.4 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 CDJ95240.1 - 0.02 14.6 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CDJ95240.1 - 0.061 13.7 0.0 1.2 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.6 CDJ95240.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DSPc PF00782.20 CDJ95242.1 - 2.1e-05 24.3 0.1 2.7e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain VWA PF00092.28 CDJ95243.1 - 2.3e-15 57.3 0.0 1.3e-14 54.9 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 CDJ95243.1 - 6.6e-11 42.8 0.0 6.6e-11 42.8 0.0 2.6 4 0 0 4 4 4 1 von Willebrand factor type A domain Beta-lactamase PF00144.24 CDJ95244.1 - 1.5e-55 188.7 0.0 2e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase PF00144.24 CDJ95245.1 - 5.2e-58 196.9 0.0 6.4e-58 196.6 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Recep_L_domain PF01030.24 CDJ95246.1 - 4.9e-08 33.1 0.0 0.00083 19.5 0.0 2.4 2 0 0 2 2 2 2 Receptor L domain CRAL_TRIO PF00650.20 CDJ95247.1 - 0.00013 21.7 0.1 0.0019 18.0 0.0 2.5 2 1 0 2 2 2 1 CRAL/TRIO domain Vac_Fusion PF02346.16 CDJ95247.1 - 0.014 15.0 4.3 13 5.5 0.0 4.7 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 CPSase_L_D3 PF02787.19 CDJ95247.1 - 0.042 14.2 3.9 0.19 12.1 0.1 3.2 2 1 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Spectrin PF00435.21 CDJ95247.1 - 0.77 10.3 26.8 0.11 13.0 3.2 5.3 3 2 1 5 5 5 0 Spectrin repeat FlaC_arch PF05377.11 CDJ95247.1 - 4.7 7.7 8.4 18 5.8 0.3 4.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Pkinase_Tyr PF07714.17 CDJ95248.1 - 5.1e-65 219.3 0.0 7.7e-65 218.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ95248.1 - 4.4e-40 137.7 0.0 8.4e-40 136.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CDJ95248.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF512 PF04459.12 CDJ95249.1 - 0.15 11.3 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF512) CPSF73-100_C PF11718.8 CDJ95249.1 - 0.16 11.5 0.6 0.19 11.2 0.6 1.1 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term AAA PF00004.29 CDJ95250.1 - 5.2e-52 175.7 0.0 1.7e-39 135.3 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.18 CDJ95250.1 - 1.4e-11 44.4 0.1 7.4e-11 42.1 0.0 2.2 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_lid_3 PF17862.1 CDJ95250.1 - 9.4e-11 41.3 0.1 2.2e-10 40.2 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CDJ95250.1 - 2.3e-10 40.9 0.1 0.0049 17.1 0.0 4.5 2 2 2 4 4 4 2 AAA domain CDC48_2 PF02933.17 CDJ95250.1 - 1.2e-07 31.3 0.2 1.4e-06 28.0 0.0 2.6 3 0 0 3 3 3 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.6 CDJ95250.1 - 1.1e-06 29.1 0.0 0.048 14.0 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.14 CDJ95250.1 - 1.4e-06 28.6 0.0 1.2e-05 25.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 CDJ95250.1 - 4e-06 27.4 0.0 0.029 14.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CDJ95250.1 - 5.6e-06 26.4 0.1 0.002 18.2 0.1 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CDJ95250.1 - 3.1e-05 23.4 1.4 0.0087 15.5 0.2 3.0 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CDJ95250.1 - 4.3e-05 23.5 0.0 0.24 11.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 CDJ95250.1 - 0.00026 20.6 0.1 0.54 9.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 CDJ95250.1 - 0.00026 21.3 0.0 0.13 12.6 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 CDJ95250.1 - 0.00032 20.9 0.0 0.16 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CDJ95250.1 - 0.00062 19.6 0.0 0.13 12.0 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein RuvB_N PF05496.12 CDJ95250.1 - 0.00073 19.3 0.0 0.029 14.1 0.0 2.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 CDJ95250.1 - 0.0019 17.9 0.0 0.23 11.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 CDJ95250.1 - 0.0021 18.0 0.0 13 5.6 0.0 4.0 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea ATPase PF06745.13 CDJ95250.1 - 0.0026 17.2 0.1 0.01 15.2 0.1 2.0 2 0 0 2 2 2 1 KaiC TsaE PF02367.17 CDJ95250.1 - 0.0032 17.4 0.0 0.2 11.7 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 CDJ95250.1 - 0.0036 16.6 0.0 0.12 11.5 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain ABC_tran PF00005.27 CDJ95250.1 - 0.0077 16.7 0.0 0.1 13.1 0.0 2.7 3 0 0 3 3 2 1 ABC transporter KTI12 PF08433.10 CDJ95250.1 - 0.0095 15.4 0.0 2 7.8 0.0 2.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_7 PF12775.7 CDJ95250.1 - 0.012 15.2 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 CDJ95250.1 - 0.019 14.7 0.0 0.34 10.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CDJ95250.1 - 0.024 15.1 0.0 4.1 7.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain Parvo_NS1 PF01057.17 CDJ95250.1 - 0.053 12.6 0.0 2.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 CDJ95250.1 - 0.083 12.8 0.2 7.8 6.4 0.0 3.5 4 1 1 5 5 4 0 NACHT domain AAA_3 PF07726.11 CDJ95250.1 - 0.11 12.4 0.0 0.34 10.8 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 CDJ95250.1 - 0.15 11.8 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CDJ95250.1 - 0.24 11.7 0.5 1.4 9.2 0.1 2.4 3 1 0 3 3 2 0 AAA domain HEAT PF02985.22 CDJ95251.1 - 3e-13 48.8 13.7 0.19 12.1 0.0 10.1 11 0 0 11 11 9 3 HEAT repeat HEAT_EZ PF13513.6 CDJ95251.1 - 3.1e-12 46.7 12.2 9.2e-08 32.4 0.0 6.8 5 2 2 7 7 7 2 HEAT-like repeat IBN_N PF03810.19 CDJ95251.1 - 3.5e-10 39.7 0.4 1e-08 34.9 0.0 3.4 3 1 1 4 4 4 1 Importin-beta N-terminal domain Cnd1 PF12717.7 CDJ95251.1 - 4.3e-07 30.1 5.2 0.0085 16.2 0.0 4.2 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDJ95251.1 - 2.1e-05 24.8 8.0 0.062 13.7 0.0 6.8 5 2 3 8 8 8 1 HEAT repeats Arm PF00514.23 CDJ95251.1 - 0.00021 21.2 7.4 0.28 11.3 0.0 5.2 5 0 0 5 5 4 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 CDJ95251.1 - 0.00058 19.5 1.3 1.9 8.0 0.0 4.4 3 1 2 5 5 5 2 CLASP N terminal Cnd3 PF12719.7 CDJ95251.1 - 0.0055 15.9 2.8 0.095 11.9 0.3 3.5 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain V-ATPase_H_C PF11698.8 CDJ95251.1 - 0.012 15.7 3.8 2.4 8.3 0.2 3.1 2 0 0 2 2 2 0 V-ATPase subunit H RIX1 PF08167.12 CDJ95251.1 - 0.02 14.6 1.1 8.9 6.0 0.0 4.8 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis TAF6_C PF07571.13 CDJ95251.1 - 0.031 14.6 0.3 0.91 9.9 0.0 3.5 4 2 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain Gcn1_N PF12074.8 CDJ95251.1 - 0.038 13.3 0.1 0.18 11.0 0.1 2.2 2 0 0 2 2 2 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal DUF3385 PF11865.8 CDJ95251.1 - 0.061 13.2 8.2 1.6 8.6 0.0 4.8 3 2 1 5 5 5 0 Domain of unknown function (DUF3385) zf-C4 PF00105.18 CDJ95252.1 - 5.8e-32 110.0 15.4 1.1e-31 109.1 15.4 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Methyltrn_RNA_3 PF02598.17 CDJ95256.1 - 1.2e-66 225.2 0.0 5.2e-62 209.9 0.0 2.2 1 1 1 2 2 2 2 Putative RNA methyltransferase Bax1-I PF01027.20 CDJ95257.1 - 4.1e-25 88.8 33.0 4.7e-25 88.6 33.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Bax1-I PF01027.20 CDJ95258.1 - 0.00021 21.2 12.1 0.00028 20.8 12.1 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2070 PF09843.9 CDJ95258.1 - 0.56 8.4 10.4 0.68 8.2 10.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2101 PF09874.9 CDJ95258.1 - 2.2 7.9 8.1 3 7.5 8.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) DUF2721 PF11026.8 CDJ95259.1 - 0.012 15.5 9.1 0.014 15.2 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF2157 PF09925.9 CDJ95259.1 - 0.069 12.9 3.5 0.077 12.8 3.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) DuoxA PF10204.9 CDJ95259.1 - 0.16 10.9 6.2 0.23 10.4 6.2 1.2 1 0 0 1 1 1 0 Dual oxidase maturation factor VWA PF00092.28 CDJ95260.1 - 7.4e-21 75.2 0.1 1.6e-20 74.1 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CDJ95260.1 - 1e-09 39.0 0.1 6.6e-09 36.4 0.1 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain NAD_binding_10 PF13460.6 CDJ95262.1 - 1.5e-09 38.0 0.0 2.3e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CDJ95262.1 - 1.7e-09 37.5 0.0 2.7e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CDJ95262.1 - 4e-08 32.6 0.0 1.7e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CDJ95262.1 - 5.1e-06 25.8 0.0 1.6e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 CDJ95262.1 - 0.00052 19.6 0.0 0.00081 19.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 CDJ95262.1 - 0.00068 18.9 0.0 2.8 7.0 0.0 3.1 2 1 1 3 3 3 2 Male sterility protein adh_short PF00106.25 CDJ95262.1 - 0.09 12.2 0.0 0.17 11.3 0.0 1.4 1 1 0 1 1 1 0 short chain dehydrogenase IQ PF00612.27 CDJ95263.1 - 2.2e-11 42.5 24.8 0.0017 17.9 2.8 5.3 4 1 1 5 5 5 4 IQ calmodulin-binding motif PAN_3 PF08277.12 CDJ95264.1 - 0.27 11.1 4.1 0.19 11.6 2.8 1.5 1 1 0 1 1 1 0 PAN-like domain Zona_pellucida PF00100.23 CDJ95265.1 - 7.1e-17 62.1 0.3 8.1e-12 45.5 0.1 2.2 2 0 0 2 2 2 2 Zona pellucida-like domain Methyltransf_21 PF05050.12 CDJ95266.1 - 7.5e-16 58.6 0.0 9.3e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase FkbM domain Ion_trans_2 PF07885.16 CDJ95267.1 - 3.2e-22 78.3 17.5 5.8e-13 48.6 0.4 3.2 3 0 0 3 3 3 2 Ion channel TssO PF17561.2 CDJ95267.1 - 0.0038 17.4 0.1 0.0038 17.4 0.1 2.2 2 0 0 2 2 2 1 Type VI secretion system, TssO Ion_trans PF00520.31 CDJ95267.1 - 0.0051 16.1 12.7 0.071 12.3 0.5 2.3 1 1 0 2 2 2 2 Ion transport protein DUF3671 PF12420.8 CDJ95267.1 - 0.2 11.7 6.7 0.49 10.5 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function MgtE PF01769.16 CDJ95267.1 - 0.33 11.3 4.7 0.19 12.1 2.4 1.8 2 0 0 2 2 2 0 Divalent cation transporter CX PF01705.19 CDJ95268.1 - 1.5e-16 60.7 6.8 2.2e-16 60.2 6.8 1.2 1 0 0 1 1 1 1 CX module DUF4688 PF15752.5 CDJ95268.1 - 0.24 10.6 0.4 0.34 10.1 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4688) RT_RNaseH PF17917.1 CDJ95269.1 - 1.4e-34 118.6 0.0 2.7e-34 117.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ95269.1 - 7.6e-32 109.3 0.0 2.9e-31 107.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ95269.1 - 8.2e-15 54.7 0.0 2.8e-14 52.9 0.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 CDJ95269.1 - 1.1e-11 45.0 0.0 2.7e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CDJ95269.1 - 3.6e-09 36.5 0.0 5.4e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3783 PF12646.7 CDJ95269.1 - 0.11 12.4 0.0 0.43 10.6 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) gag-asp_proteas PF13975.6 CDJ95270.1 - 1.2e-05 25.7 0.0 4.3e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 CDJ95270.1 - 9.1e-05 22.4 1.8 0.00016 21.6 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle RVP PF00077.20 CDJ95270.1 - 0.029 14.7 0.1 0.22 11.9 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ95270.1 - 0.14 12.9 0.0 0.41 11.3 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_2 PF13696.6 CDJ95270.1 - 0.43 10.5 1.5 0.76 9.7 1.5 1.3 1 0 0 1 1 1 0 Zinc knuckle EGF_CA PF07645.15 CDJ95271.1 - 2e-10 40.7 5.4 2e-10 40.7 5.4 3.4 3 0 0 3 3 3 1 Calcium-binding EGF domain EGF_3 PF12947.7 CDJ95271.1 - 0.0013 18.8 2.7 0.0013 18.8 2.7 3.4 3 0 0 3 3 3 1 EGF domain cEGF PF12662.7 CDJ95271.1 - 0.013 15.4 0.3 0.013 15.4 0.3 3.2 3 0 0 3 3 3 0 Complement Clr-like EGF-like EB PF01683.18 CDJ95271.1 - 0.085 13.2 31.1 0.42 10.9 4.9 3.3 2 1 1 3 3 3 0 EB module EGF_MSP1_1 PF12946.7 CDJ95271.1 - 8 6.6 26.3 0.25 11.4 4.1 3.3 3 0 0 3 3 3 0 MSP1 EGF domain 1 Laminin_G_2 PF02210.24 CDJ95273.1 - 6.2e-62 207.8 0.0 1.8e-20 73.8 0.0 3.2 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.23 CDJ95273.1 - 1.8e-49 167.3 0.0 3.6e-17 62.8 0.0 3.3 3 0 0 3 3 3 3 Laminin G domain Laminin_G_3 PF13385.6 CDJ95273.1 - 0.00015 21.9 0.0 0.029 14.5 0.0 3.0 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily FXa_inhibition PF14670.6 CDJ95273.1 - 0.00097 19.4 4.6 0.00097 19.4 4.6 2.4 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site Myosin_head PF00063.21 CDJ95274.1 - 6e-243 808.0 3.6 7.2e-243 807.7 3.6 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 CDJ95274.1 - 3.1e-06 26.5 30.7 0.00034 20.2 1.6 5.3 6 0 0 6 6 6 3 IQ calmodulin-binding motif AAA_16 PF13191.6 CDJ95274.1 - 0.0036 17.7 3.1 0.014 15.8 0.4 3.0 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CDJ95274.1 - 0.024 14.9 0.2 0.18 12.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain SoxZ PF08770.11 CDJ95274.1 - 0.062 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Sulphur oxidation protein SoxZ ABC_tran PF00005.27 CDJ95274.1 - 0.11 13.0 0.0 0.4 11.2 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 CDJ95274.1 - 0.37 10.0 3.5 2 7.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin BTB_2 PF02214.22 CDJ95276.1 - 6.7e-21 74.5 0.0 2.4e-20 72.7 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain EF-hand_14 PF17959.1 CDJ95277.1 - 0.028 14.7 0.2 12 6.3 0.0 3.1 4 0 0 4 4 4 0 EF-hand domain Peptidase_M13_N PF05649.13 CDJ95277.1 - 0.084 12.5 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M13 FAM104 PF15434.6 CDJ95277.1 - 0.086 13.4 0.3 0.18 12.4 0.3 1.5 1 0 0 1 1 1 0 Family 104 PUNUT PF16913.5 CDJ95278.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Purine nucleobase transmembrane transport PUNUT PF16913.5 CDJ95279.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Purine nucleobase transmembrane transport HTH_48 PF17906.1 CDJ95280.1 - 1.4e-17 63.5 0.1 1.9e-17 63.1 0.1 1.2 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_50 PF18024.1 CDJ95280.1 - 2.1e-05 24.0 0.0 3.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 CDJ95280.1 - 0.013 15.3 0.0 0.84 9.5 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain LZ_Tnp_IS481 PF13011.6 CDJ95280.1 - 0.042 14.4 1.5 7.6 7.1 0.0 2.2 1 1 1 2 2 2 0 leucine-zipper of insertion element IS481 SNF PF00209.18 CDJ95281.1 - 4.4e-09 35.6 0.1 4.4e-09 35.6 0.1 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family EBP PF05241.12 CDJ95282.1 - 8.4e-08 31.9 9.1 1e-07 31.6 9.1 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2244 PF10003.9 CDJ95282.1 - 0.18 11.5 0.2 0.18 11.5 0.2 2.5 2 1 1 3 3 3 0 Integral membrane protein (DUF2244) DUF4386 PF14329.6 CDJ95282.1 - 3.8 7.3 10.3 0.27 11.1 0.7 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4386) 7tm_1 PF00001.21 CDJ95283.1 - 2.4e-17 63.1 1.6 3e-17 62.8 1.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ95283.1 - 0.0032 16.9 2.1 0.0046 16.4 2.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx STE3 PF02076.15 CDJ95283.1 - 0.12 11.6 4.1 0.17 11.0 3.9 1.4 1 1 0 1 1 1 0 Pheromone A receptor YlaC PF10777.9 CDJ95283.1 - 0.16 11.8 2.1 0.18 11.6 0.1 1.9 1 1 1 2 2 2 0 Inner membrane protein YlaC Myosin_head PF00063.21 CDJ95284.1 - 1.6e-293 975.1 2.6 1.6e-293 975.1 2.6 3.3 4 1 1 5 5 5 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CDJ95284.1 - 1.7e-126 423.5 250.9 2.2e-126 423.2 250.9 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 CDJ95284.1 - 5.2e-13 48.6 7.0 1.5e-12 47.1 7.0 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.21 CDJ95284.1 - 4.5e-05 23.2 37.2 4.5e-05 23.2 37.2 8.2 1 1 5 6 6 6 2 Intermediate filament protein DUF3450 PF11932.8 CDJ95284.1 - 0.0044 16.4 4.9 0.0044 16.4 4.9 12.6 1 1 10 12 12 12 2 Protein of unknown function (DUF3450) TRAF_BIRC3_bd PF16673.5 CDJ95284.1 - 0.0063 16.3 0.9 0.0063 16.3 0.9 9.9 7 4 4 11 11 11 1 TNF receptor-associated factor BIRC3 binding domain AAA_19 PF13245.6 CDJ95284.1 - 0.31 11.4 0.0 0.31 11.4 0.0 5.2 4 1 0 4 4 4 0 AAA domain AAA_22 PF13401.6 CDJ95284.1 - 0.48 10.7 0.0 0.48 10.7 0.0 6.8 5 3 1 6 6 6 0 AAA domain Myosin_head PF00063.21 CDJ95285.1 - 7.1e-296 982.9 6.7 7.1e-296 982.9 6.7 2.2 2 0 0 2 2 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CDJ95285.1 - 5.5e-160 534.4 264.1 7.5e-160 534.0 264.1 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 CDJ95285.1 - 4.4e-15 55.2 1.3 1.2e-14 53.9 1.3 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Spc7 PF08317.11 CDJ95285.1 - 7.1e-05 21.8 6.8 7.1e-05 21.8 6.8 11.2 2 1 11 13 13 13 4 Spc7 kinetochore protein Filament PF00038.21 CDJ95285.1 - 0.0002 21.1 41.6 0.0002 21.1 41.6 8.1 1 1 2 5 5 5 1 Intermediate filament protein BRE1 PF08647.11 CDJ95285.1 - 0.0017 18.4 12.0 0.0017 18.4 12.0 15.1 3 3 12 15 15 12 3 BRE1 E3 ubiquitin ligase DUF745 PF05335.13 CDJ95285.1 - 0.0049 16.6 15.7 0.0049 16.6 15.7 11.9 3 1 15 18 18 15 3 Protein of unknown function (DUF745) ATG16 PF08614.11 CDJ95285.1 - 0.0063 16.8 42.8 0.0063 16.8 42.8 10.7 3 1 8 11 11 8 3 Autophagy protein 16 (ATG16) AAA_19 PF13245.6 CDJ95285.1 - 0.25 11.7 0.0 0.25 11.7 0.0 3.2 3 1 0 3 3 1 0 AAA domain MscS_porin PF12795.7 CDJ95285.1 - 0.34 10.4 249.2 0.059 12.9 33.6 9.5 1 1 4 8 8 8 0 Mechanosensitive ion channel porin domain AAA_22 PF13401.6 CDJ95285.1 - 0.5 10.6 0.0 0.5 10.6 0.0 7.6 5 3 2 7 7 6 0 AAA domain EMC1_C PF07774.13 CDJ95286.1 - 3.9e-69 232.6 0.0 7.4e-69 231.7 0.0 1.5 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 CDJ95286.1 - 5e-23 81.9 1.0 1.6e-13 50.8 1.3 3.2 3 0 0 3 3 3 3 PQQ-like domain PQQ PF01011.21 CDJ95286.1 - 5.7e-08 32.3 1.5 0.0044 16.9 0.1 4.8 4 0 0 4 4 4 1 PQQ enzyme repeat PQQ_3 PF13570.6 CDJ95286.1 - 0.5 10.9 6.8 18 5.9 0.0 5.0 6 0 0 6 6 6 0 PQQ-like domain Surp PF01805.20 CDJ95287.1 - 5.3e-14 52.0 0.1 1.3e-13 50.7 0.1 1.7 1 0 0 1 1 1 1 Surp module G-patch PF01585.23 CDJ95287.1 - 2.4e-11 43.3 3.6 6.5e-11 41.9 3.6 1.7 1 0 0 1 1 1 1 G-patch domain CTD_bind PF04818.13 CDJ95287.1 - 4.3e-10 40.3 0.1 1.3e-09 38.8 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Apt1 PF10351.9 CDJ95287.1 - 0.053 12.4 15.8 0.089 11.6 15.8 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ95287.1 - 5.5 5.7 12.5 9 4.9 12.5 1.3 1 0 0 1 1 1 0 Presenilin WW PF00397.26 CDJ95288.1 - 0.014 15.5 1.7 0.041 14.0 1.7 1.8 1 0 0 1 1 1 0 WW domain zf-C2H2 PF00096.26 CDJ95289.1 - 2.4e-09 37.1 42.5 0.036 14.5 2.8 8.2 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ95289.1 - 7.1e-07 29.5 45.2 0.032 15.1 2.3 8.7 8 0 0 8 8 8 4 C2H2-type zinc finger zf-Di19 PF05605.12 CDJ95289.1 - 0.01 16.1 34.2 4 7.8 1.6 7.5 7 0 0 7 7 7 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 CDJ95289.1 - 0.025 14.9 0.4 0.025 14.9 0.4 3.2 2 1 0 2 2 2 0 C2H2-type zinc ribbon zf_Hakai PF18408.1 CDJ95289.1 - 0.081 12.7 0.9 0.76 9.5 0.3 3.0 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain TRAF6_Z2 PF18048.1 CDJ95289.1 - 0.2 11.8 10.5 0.78 9.9 0.1 4.1 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zf_C2H2_ZHX PF18387.1 CDJ95289.1 - 0.27 10.9 21.6 0.3 10.7 0.0 5.8 5 1 1 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 CDJ95289.1 - 0.72 10.2 33.0 0.21 11.9 0.9 6.7 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 CDJ95289.1 - 1.3 9.7 10.6 12 6.7 0.1 5.0 5 0 0 5 5 5 0 FOXP coiled-coil domain zf-WRNIP1_ubi PF18279.1 CDJ95289.1 - 2 9.2 5.6 4.5 8.2 0.8 3.0 3 0 0 3 3 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-C2H2_3rep PF18868.1 CDJ95289.1 - 3.2 8.4 25.9 0.15 12.8 1.3 5.6 5 2 2 7 7 5 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_9 PF16293.5 CDJ95289.1 - 3.4 7.6 14.0 0.47 10.3 0.5 5.2 6 0 0 6 6 6 0 C2H2 type zinc-finger (1 copy) Prenyltransf PF01255.19 CDJ95290.1 - 2e-71 240.1 0.0 2.4e-71 239.9 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase rRNA_methylase PF06962.12 CDJ95290.1 - 0.18 11.8 0.0 0.98 9.4 0.0 2.1 1 1 1 2 2 2 0 Putative rRNA methylase PCI PF01399.27 CDJ95291.1 - 1.8e-05 25.2 0.0 4.4e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 PCI domain DUF1674 PF07896.12 CDJ95292.1 - 8e-18 64.7 8.3 4.1e-17 62.4 8.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Oxysterol_BP PF01237.18 CDJ95294.1 - 8.3e-76 255.2 0.3 7e-74 248.9 0.3 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein TauE PF01925.19 CDJ95295.1 - 6.1e-15 55.5 10.8 8.8e-15 55.0 10.8 1.2 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF1656 PF07869.12 CDJ95295.1 - 0.31 11.1 5.1 1.3 9.1 5.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) RVT_1 PF00078.27 CDJ95296.1 - 1.1e-39 136.3 0.0 2e-39 135.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Helicase_C_3 PF13625.6 CDJ95296.1 - 0.036 14.2 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Helicase conserved C-terminal domain BLOC1_2 PF10046.9 CDJ95296.1 - 0.061 13.6 0.2 1.3 9.4 0.0 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-CCHC PF00098.23 CDJ95298.1 - 1.2e-06 28.3 2.4 1.2e-06 28.3 2.4 1.9 2 0 0 2 2 2 1 Zinc knuckle gag-asp_proteas PF13975.6 CDJ95298.1 - 0.001 19.6 0.0 0.0028 18.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC_2 PF13696.6 CDJ95298.1 - 0.045 13.6 1.1 0.045 13.6 1.1 1.9 2 0 0 2 2 2 0 Zinc knuckle VPS13_mid_rpt PF16910.5 CDJ95298.1 - 0.11 11.9 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Repeating coiled region of VPS13 zf-CCHC_4 PF14392.6 CDJ95298.1 - 0.12 12.1 0.8 0.3 10.9 0.2 1.9 2 0 0 2 2 2 0 Zinc knuckle Asp_protease_2 PF13650.6 CDJ95298.1 - 0.14 12.8 0.0 0.46 11.2 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease 7TM_GPCR_Srw PF10324.9 CDJ95299.1 - 1.7e-17 63.7 9.8 1.9e-17 63.5 9.8 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw GnRH PF00446.17 CDJ95299.1 - 0.11 12.9 3.2 0.24 11.9 3.2 1.6 1 0 0 1 1 1 0 Gonadotropin-releasing hormone 7tm_1 PF00001.21 CDJ95299.1 - 1.4 8.1 13.9 0.091 12.1 7.7 1.9 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) Helicase_C PF00271.31 CDJ95300.1 - 1.1e-26 93.3 0.2 1.6e-26 92.8 0.2 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain tRNA-synt_1b PF00579.25 CDJ95300.1 - 0.012 15.0 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) PsaL PF02605.15 CDJ95301.1 - 0.068 12.8 0.0 0.076 12.7 0.0 1.0 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI Ribosomal_S21 PF01165.20 CDJ95303.1 - 0.037 13.7 0.7 3.5 7.4 0.1 2.1 2 0 0 2 2 2 0 Ribosomal protein S21 HTH_48 PF17906.1 CDJ95304.1 - 2.9e-17 62.5 0.1 4.4e-17 61.9 0.1 1.3 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_Tnp_IS630 PF01710.16 CDJ95304.1 - 0.086 12.9 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Transposase HTH_23 PF13384.6 CDJ95304.1 - 0.12 12.2 0.0 0.57 10.1 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_32 PF13565.6 CDJ95304.1 - 0.13 12.9 0.0 0.18 12.4 0.0 1.4 1 1 0 1 1 1 0 Homeodomain-like domain zf-C3HC4_2 PF13923.6 CDJ95305.1 - 1.9e-10 40.4 9.2 2.5e-10 40.0 6.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ95305.1 - 1.1e-08 34.8 5.7 1.1e-08 34.8 5.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ95305.1 - 1.3e-08 34.5 6.9 1.3e-08 34.5 6.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ95305.1 - 3.6e-08 33.6 7.1 3.6e-08 33.6 7.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CDJ95305.1 - 9.3e-07 28.8 6.9 9.3e-07 28.8 6.9 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDJ95305.1 - 9.5e-07 28.9 8.0 9.5e-07 28.9 8.0 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CDJ95305.1 - 1.3e-06 28.2 6.2 1.3e-06 28.2 6.2 2.2 2 1 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDJ95305.1 - 0.00076 19.3 9.5 0.00076 19.3 9.5 2.2 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CDJ95305.1 - 0.0027 17.5 11.5 0.0075 16.0 8.1 2.8 2 1 1 3 3 3 1 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 CDJ95305.1 - 0.025 14.7 9.4 0.04 14.0 8.8 1.7 1 1 1 2 2 2 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 CDJ95305.1 - 0.058 13.1 0.8 0.058 13.1 0.8 2.8 2 0 0 2 2 2 0 RING-like zinc finger zf-rbx1 PF12678.7 CDJ95305.1 - 0.16 12.2 9.6 0.14 12.5 6.7 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger domain C5HCH PF17982.1 CDJ95305.1 - 1.1 9.4 5.6 0.26 11.5 2.2 1.8 1 1 1 2 2 2 0 NSD Cys-His rich domain zf-P11 PF03854.14 CDJ95305.1 - 9 6.0 8.4 2 8.1 2.4 2.3 1 1 1 2 2 2 0 P-11 zinc finger TMEM154 PF15102.6 CDJ95306.1 - 0.01 15.7 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family PBP_sp32 PF07222.12 CDJ95306.1 - 0.09 12.2 0.4 0.15 11.5 0.2 1.4 1 1 0 1 1 1 0 Proacrosin binding protein sp32 MLANA PF14991.6 CDJ95306.1 - 0.11 12.8 2.2 1 9.6 2.1 2.3 1 1 0 1 1 1 0 Protein melan-A Chordopox_A13L PF05961.11 CDJ95306.1 - 0.3 11.4 1.6 0.32 11.3 0.0 1.8 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Cpn60_TCP1 PF00118.24 CDJ95307.1 - 1.6e-89 300.8 17.3 3.2e-89 299.8 17.3 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Gag_p15 PF08723.10 CDJ95307.1 - 0.04 14.1 1.0 0.71 10.1 0.0 3.0 3 1 1 4 4 4 0 Gag protein p15 tRNA_int_endo PF01974.17 CDJ95307.1 - 0.17 12.0 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 tRNA intron endonuclease, catalytic C-terminal domain Cpn10 PF00166.21 CDJ95308.1 - 1.8e-33 114.4 0.0 2.1e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Polyketide_cyc PF03364.20 CDJ95309.1 - 3.7e-18 66.0 0.0 4.5e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 CDJ95309.1 - 0.0024 18.2 0.0 0.0032 17.8 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport zf-C2H2_6 PF13912.6 CDJ95310.1 - 7.8e-05 22.6 0.4 0.00021 21.2 0.4 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CDJ95310.1 - 5.1 7.5 8.3 4.3 7.7 0.5 2.7 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Med11 PF10280.9 CDJ95311.1 - 1.1e-11 45.3 3.0 1.3e-11 45.1 3.0 1.1 1 0 0 1 1 1 1 Mediator complex protein DHR10 PF18595.1 CDJ95311.1 - 0.012 15.6 3.8 0.012 15.6 3.8 1.5 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain UPF0242 PF06785.11 CDJ95311.1 - 0.017 15.2 2.7 0.02 15.0 2.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Seryl_tRNA_N PF02403.22 CDJ95311.1 - 0.025 14.8 1.0 0.041 14.1 1.0 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain WH2 PF02205.20 CDJ95312.1 - 4.9e-09 35.7 0.5 1.1e-08 34.6 0.5 1.6 1 0 0 1 1 1 1 WH2 motif CAP_N PF01213.19 CDJ95312.1 - 0.0026 17.3 8.2 0.0026 17.3 8.2 5.9 2 1 1 3 3 3 1 Adenylate cyclase associated (CAP) N terminal Shugoshin_C PF07557.11 CDJ95313.1 - 3.6e-07 29.8 2.0 3.6e-07 29.8 2.0 2.0 2 0 0 2 2 2 1 Shugoshin C terminus VCX_VCY PF15231.6 CDJ95313.1 - 0.0041 17.8 1.7 0.71 10.6 0.1 3.1 3 0 0 3 3 3 1 Variable charge X/Y family JAKMIP_CC3 PF16034.5 CDJ95313.1 - 0.0095 15.9 1.0 0.02 14.9 1.0 1.5 1 0 0 1 1 1 1 JAKMIP CC3 domain Phasin PF05597.11 CDJ95313.1 - 0.018 15.1 1.1 0.039 14.0 1.1 1.6 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SlyX PF04102.12 CDJ95313.1 - 0.043 14.4 0.2 0.16 12.6 0.2 2.0 1 0 0 1 1 1 0 SlyX DUF4715 PF15835.5 CDJ95313.1 - 0.05 13.7 0.2 0.094 12.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4715) DUF5082 PF16888.5 CDJ95313.1 - 0.13 12.6 1.8 0.36 11.1 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DivIC PF04977.15 CDJ95313.1 - 0.29 10.9 2.1 0.68 9.7 2.0 1.7 1 1 0 1 1 1 0 Septum formation initiator Metallophos PF00149.28 CDJ95315.1 - 1.2e-23 84.7 1.1 2.9e-23 83.4 1.1 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.32 CDJ95315.1 - 3.7e-12 44.9 0.5 7.9e-05 21.9 0.1 4.1 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 CDJ95315.1 - 1.6e-11 43.1 0.9 8.2e-05 22.2 0.1 3.9 4 0 0 4 4 4 2 EF-hand domain PPP5 PF08321.12 CDJ95315.1 - 1.9e-11 44.1 1.2 7e-11 42.3 0.0 2.6 3 0 0 3 3 3 1 PPP5 TPR repeat region EF-hand_7 PF13499.6 CDJ95315.1 - 2.4e-11 43.9 0.0 2.1e-05 24.8 0.0 3.4 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ95315.1 - 6.9e-09 34.8 3.0 0.00021 20.7 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CDJ95315.1 - 1.6e-05 24.7 1.6 0.0032 17.3 0.2 2.7 1 1 1 2 2 2 2 EF-hand domain pair IQ PF00612.27 CDJ95315.1 - 0.0042 16.7 2.7 0.0096 15.6 2.7 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Tn916-Xis PF09035.10 CDJ95315.1 - 0.1 12.8 0.3 0.35 11.1 0.0 1.9 2 0 0 2 2 2 0 Excisionase from transposon Tn916 Srg PF02118.21 CDJ95317.1 - 7.7e-41 140.6 25.1 9.2e-41 140.3 25.1 1.1 1 0 0 1 1 1 1 Srg family chemoreceptor 7TM_GPCR_Srx PF10328.9 CDJ95317.1 - 0.0029 17.3 23.1 0.01 15.5 23.1 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.15 CDJ95317.1 - 0.51 10.3 12.1 0.044 13.8 5.1 2.5 1 1 1 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa 7tm_1 PF00001.21 CDJ95317.1 - 0.89 8.8 9.7 0.21 10.9 5.3 2.0 1 1 1 3 3 3 0 7 transmembrane receptor (rhodopsin family) WD40 PF00400.32 CDJ95318.1 - 4.9e-12 46.2 0.1 8.2e-07 29.6 0.1 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ95318.1 - 0.015 15.6 0.0 8.6 6.7 0.0 3.4 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CDJ95318.1 - 0.022 13.5 0.0 0.31 9.7 0.0 2.3 1 1 2 3 3 3 0 Nup133 N terminal like US22 PF02393.16 CDJ95318.1 - 0.059 13.7 0.3 12 6.2 0.0 2.5 1 1 1 2 2 2 0 US22 like RAB3GAP2_N PF14655.6 CDJ95318.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Vma12 PF11712.8 CDJ95319.1 - 1e-31 109.9 0.1 1.4e-31 109.4 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF996 PF06195.13 CDJ95319.1 - 0.0063 16.8 0.3 0.01 16.1 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF996) Tmemb_cc2 PF10267.9 CDJ95319.1 - 0.072 12.2 0.1 0.096 11.8 0.1 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein RNA_polI_A34 PF08208.11 CDJ95320.1 - 2.6e-08 34.2 8.6 4.4e-08 33.5 0.1 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase I subunit RPA34.5 RNase_H2_suC PF08615.11 CDJ95321.1 - 1.6e-10 41.3 0.1 3.7e-09 36.9 0.0 2.0 1 1 1 2 2 2 2 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Torsin PF06309.11 CDJ95322.1 - 3.4e-46 156.4 0.1 6.6e-46 155.5 0.1 1.5 1 0 0 1 1 1 1 Torsin AAA_22 PF13401.6 CDJ95322.1 - 0.00023 21.4 0.1 0.0047 17.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 CDJ95322.1 - 0.00024 21.5 0.0 0.00037 20.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 CDJ95322.1 - 0.068 13.2 0.1 0.48 10.4 0.0 2.1 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 CDJ95322.1 - 0.16 11.7 0.0 0.4 10.4 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.22 CDJ95322.1 - 0.17 11.1 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Piwi PF02171.17 CDJ95323.1 - 9.3e-65 218.8 0.0 1.4e-64 218.2 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 CDJ95323.1 - 1.2e-16 60.8 0.1 3.6e-16 59.2 0.1 1.9 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 CDJ95323.1 - 0.00011 22.4 0.1 0.00063 19.9 0.0 2.3 2 0 0 2 2 2 1 Mid domain of argonaute ArgoL2 PF16488.5 CDJ95323.1 - 0.00022 21.5 0.0 0.00069 19.9 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain Ribosomal_L27e PF01777.18 CDJ95323.1 - 0.13 12.6 0.4 38 4.7 0.0 3.9 3 0 0 3 3 3 0 Ribosomal L27e protein family RT_RNaseH_2 PF17919.1 CDJ95324.1 - 8.7e-35 118.8 0.0 1.9e-33 114.4 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ95324.1 - 6.9e-31 106.7 0.0 1.2e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ95324.1 - 2.1e-23 82.8 0.0 5.3e-23 81.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CDJ95324.1 - 2.9e-16 59.7 0.0 7.1e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ95324.1 - 2.9e-14 52.9 0.0 5.4e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CDJ95324.1 - 3.9e-05 23.3 0.1 0.002 17.8 0.0 3.2 4 0 0 4 4 4 1 Integrase core domain zf-H2C2 PF09337.10 CDJ95324.1 - 0.002 18.3 0.0 0.0039 17.4 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Mucin PF01456.17 CDJ95324.1 - 5.8 6.9 15.7 13 5.8 15.7 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein RVT_1 PF00078.27 CDJ95325.1 - 0.0076 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PNMA PF14893.6 CDJ95326.1 - 4.9e-05 22.9 0.1 6.8e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 PNMA DUF4882 PF16223.5 CDJ95326.1 - 0.073 12.3 0.0 0.097 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4882) Metal_hydrol PF10118.9 CDJ95326.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Predicted metal-dependent hydrolase DUF3685 PF12452.8 CDJ95326.1 - 0.16 11.6 0.2 4.1 7.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3685) COX6B PF02297.17 CDJ95327.1 - 1.9e-05 24.8 3.7 3.8e-05 23.8 3.7 1.5 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb 7TM_GPCR_Srw PF10324.9 CDJ95330.1 - 1.2e-07 31.4 8.6 2.2e-07 30.5 8.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 CDJ95330.1 - 0.00028 20.4 13.3 0.001 18.5 13.3 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 CDJ95330.1 - 0.019 14.3 11.7 0.028 13.7 11.7 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 CDJ95331.1 - 1.7e-05 24.3 11.8 1.7e-05 24.3 11.8 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PC4 PF02229.16 CDJ95332.1 - 4.7e-24 83.8 0.1 1.1e-23 82.6 0.1 1.6 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) SOG2 PF10428.9 CDJ95332.1 - 0.36 10.0 4.6 0.36 10.0 4.6 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 CDJ95332.1 - 0.61 8.8 3.8 0.54 9.0 3.8 1.1 1 0 0 1 1 1 0 Presenilin Rtf2 PF04641.12 CDJ95332.1 - 0.97 8.7 12.0 1.2 8.4 12.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger RNA_pol_Rpc4 PF05132.14 CDJ95332.1 - 1.3 9.4 9.9 1.8 9.0 9.9 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Sec62 PF03839.16 CDJ95332.1 - 1.4 8.3 7.1 1.8 8.0 7.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 CDC45 PF02724.14 CDJ95332.1 - 1.5 7.0 6.3 1.2 7.3 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 CDJ95332.1 - 1.8 7.3 8.0 1.6 7.4 8.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AP3D1 PF06375.11 CDJ95332.1 - 1.8 8.8 18.6 2.6 8.2 18.6 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Connexin PF00029.19 CDJ95332.1 - 5.2 6.8 5.7 5.6 6.7 5.7 1.2 1 0 0 1 1 1 0 Connexin DUF4637 PF15470.6 CDJ95332.1 - 5.5 6.7 12.5 3.9 7.2 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4637) bHLH-MYC_N PF14215.6 CDJ95333.1 - 0.015 15.6 1.9 0.027 14.7 1.9 1.5 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal Glyoxal_oxid_N PF07250.11 CDJ95333.1 - 0.086 12.0 2.3 0.19 10.9 2.3 1.5 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus RRM_3 PF08777.11 CDJ95334.1 - 0.033 14.2 0.1 0.042 13.9 0.1 1.1 1 0 0 1 1 1 0 RNA binding motif EGF PF00008.27 CDJ95335.1 - 3.7e-15 55.9 57.9 1.6e-05 25.1 4.3 6.5 6 0 0 6 6 6 5 EGF-like domain EGF_CA PF07645.15 CDJ95335.1 - 2.1e-08 34.2 64.6 2e-06 27.9 2.5 6.2 5 1 1 6 6 6 4 Calcium-binding EGF domain EGF_3 PF12947.7 CDJ95335.1 - 7.5e-07 29.2 55.1 0.015 15.5 1.3 5.8 5 0 0 5 5 5 4 EGF domain SEA PF01390.20 CDJ95335.1 - 0.00013 22.0 0.0 0.00033 20.7 0.0 1.6 1 0 0 1 1 1 1 SEA domain hEGF PF12661.7 CDJ95335.1 - 0.00021 21.8 9.4 0.003 18.1 3.6 7.2 7 0 0 7 7 7 4 Human growth factor-like EGF FXa_inhibition PF14670.6 CDJ95335.1 - 0.016 15.5 5.0 0.016 15.5 5.0 6.6 6 0 0 6 6 6 0 Coagulation Factor Xa inhibitory site cEGF PF12662.7 CDJ95335.1 - 0.029 14.3 1.1 0.029 14.3 1.1 6.8 7 0 0 7 7 7 0 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.11 CDJ95335.1 - 0.2 12.0 49.5 0.19 12.1 3.6 5.8 5 0 0 5 5 5 0 Pvs28 EGF domain Mucin PF01456.17 CDJ95335.1 - 1.1 9.2 11.4 3.5 7.6 11.4 1.8 1 1 0 1 1 1 0 Mucin-like glycoprotein EGF_MSP1_1 PF12946.7 CDJ95335.1 - 7 6.8 52.3 0.069 13.2 3.2 5.7 5 0 0 5 5 5 0 MSP1 EGF domain 1 LIM PF00412.22 CDJ95336.1 - 1.6e-14 53.8 4.0 2.1e-14 53.5 4.0 1.2 1 0 0 1 1 1 1 LIM domain zf-SNAP50_C PF12251.8 CDJ95336.1 - 0.062 13.0 0.4 0.069 12.8 0.4 1.2 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal zf-DNA_Pol PF08996.10 CDJ95336.1 - 0.2 11.4 3.0 0.22 11.3 3.0 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger zinc_ribbon_9 PF14369.6 CDJ95336.1 - 0.39 11.0 6.4 1.4 9.3 0.1 2.6 2 1 0 2 2 2 0 zinc-ribbon zf_UBZ PF18439.1 CDJ95336.1 - 0.74 9.5 0.1 0.74 9.5 0.1 3.5 3 1 0 3 3 3 0 Ubiquitin-Binding Zinc Finger RRM_1 PF00076.22 CDJ95338.1 - 3.8e-16 58.7 0.0 5.3e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ETC_C1_NDUFA5 PF04716.14 CDJ95339.1 - 3.5e-24 84.4 0.1 5.9e-24 83.7 0.1 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region UPF0047 PF01894.17 CDJ95339.1 - 0.14 12.3 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0047 RUN PF02759.19 CDJ95340.1 - 6e-16 58.6 0.1 8.6e-16 58.1 0.1 1.2 1 0 0 1 1 1 1 RUN domain FYVE PF01363.21 CDJ95341.1 - 7.4e-20 70.9 11.3 1.4e-19 70.0 11.3 1.5 1 0 0 1 1 1 1 FYVE zinc finger RUN PF02759.19 CDJ95341.1 - 3.7e-15 56.1 0.1 3.7e-15 56.1 0.1 2.3 3 0 0 3 3 3 1 RUN domain CALCOCO1 PF07888.11 CDJ95341.1 - 0.016 14.1 41.0 21 3.8 40.9 2.2 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like IBR PF01485.21 CDJ95341.1 - 0.062 13.5 5.8 0.19 12.0 5.8 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Vps5 PF09325.10 CDJ95341.1 - 0.065 12.8 24.9 0.78 9.2 1.5 3.3 2 1 1 3 3 3 0 Vps5 C terminal like DZR PF12773.7 CDJ95341.1 - 1.2 9.2 11.1 87 3.3 11.1 2.5 1 1 0 1 1 1 0 Double zinc ribbon C1_2 PF03107.16 CDJ95341.1 - 1.5 9.2 9.6 0.2 12.0 5.4 1.8 2 0 0 2 2 1 0 C1 domain zf-RING_2 PF13639.6 CDJ95341.1 - 3.4 8.1 10.3 7.7 6.9 10.3 1.7 1 0 0 1 1 1 0 Ring finger domain Tropomyosin_1 PF12718.7 CDJ95341.1 - 3.9 7.6 47.9 0.049 13.8 23.4 3.2 1 1 2 3 3 3 0 Tropomyosin like Jnk-SapK_ap_N PF09744.9 CDJ95341.1 - 5.5 7.2 47.5 0.95 9.7 13.8 4.2 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 zf-B_box PF00643.24 CDJ95341.1 - 7.7 6.8 9.4 6.9 6.9 5.6 2.5 2 0 0 2 2 2 0 B-box zinc finger DUF1057 PF06342.12 CDJ95342.1 - 6.4e-61 206.0 0.0 2.6e-60 204.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Hydrolase_4 PF12146.8 CDJ95342.1 - 3.4e-08 33.0 0.0 2.2e-07 30.4 0.0 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ95342.1 - 4.8e-08 33.0 0.0 8.2e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ95342.1 - 5.6e-08 33.7 0.0 7.6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 CDJ95342.1 - 0.095 12.4 0.1 4 7.1 0.0 2.2 1 1 1 2 2 2 0 PGAP1-like protein Thioesterase PF00975.20 CDJ95342.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain UNC-93 PF05978.16 CDJ95343.1 - 5.3e-47 159.4 13.8 5.3e-47 159.4 13.8 2.8 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 UNC-93 PF05978.16 CDJ95344.1 - 1.4e-49 167.8 9.4 4.5e-49 166.2 9.4 1.9 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 An_peroxidase PF03098.15 CDJ95346.1 - 0 1034.1 0.5 9.1e-178 592.1 0.0 5.0 3 1 1 4 4 4 4 Animal haem peroxidase CLN3 PF02487.17 CDJ95347.1 - 4.7e-45 154.3 11.3 5.3e-45 154.2 11.3 1.0 1 0 0 1 1 1 1 CLN3 protein UPF0640 PF15114.6 CDJ95347.1 - 0.023 14.5 1.5 0.4 10.5 0.7 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0640 EI24 PF07264.11 CDJ95347.1 - 1 9.6 8.9 1.4 9.2 8.9 1.3 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF3481 PF11980.8 CDJ95347.1 - 4.3 7.1 5.8 1.3 8.7 2.6 1.8 2 0 0 2 2 2 0 C-terminal domain of neuropilin glycoprotein Mcl1_mid PF12341.8 CDJ95348.1 - 3.9e-50 170.9 0.4 2.4e-49 168.3 0.2 2.0 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 CDJ95348.1 - 6.6e-05 23.1 0.1 0.16 12.3 0.0 3.8 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WYL_2 PF10902.8 CDJ95348.1 - 0.11 12.9 0.0 1.1 9.6 0.1 2.3 2 0 0 2 2 2 0 WYL_2, Sm-like SH3 beta-barrel fold WD40 PF00400.32 CDJ95348.1 - 3.1 8.8 8.1 59 4.8 0.4 4.7 3 1 1 4 4 4 0 WD domain, G-beta repeat AA_permease_2 PF13520.6 CDJ95349.1 - 1.2e-61 208.9 38.9 1.6e-61 208.5 38.9 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CDJ95349.1 - 1.5e-34 119.5 33.6 2e-34 119.0 33.6 1.2 1 1 0 1 1 1 1 Amino acid permease Phosphodiest PF01663.22 CDJ95350.1 - 8.6e-55 186.7 2.4 1.6e-54 185.8 2.4 1.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CDJ95350.1 - 0.00069 19.1 0.7 0.0045 16.4 0.7 2.1 1 1 0 1 1 1 1 Sulfatase Methyltransf_31 PF13847.6 CDJ95351.1 - 6.8e-15 55.2 0.1 6.8e-11 42.2 0.1 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ95351.1 - 3.3e-13 50.2 0.1 4.5e-09 36.9 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ95351.1 - 1.3e-12 48.2 0.0 4.7e-11 43.2 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CDJ95351.1 - 3e-08 33.4 0.1 9.6e-06 25.2 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase small domain Spermine_synth PF01564.17 CDJ95351.1 - 3.2e-07 29.9 0.0 0.00056 19.4 0.0 3.5 3 1 0 3 3 3 2 Spermine/spermidine synthase domain Methyltransf_12 PF08242.12 CDJ95351.1 - 1e-05 26.2 0.1 5.4e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 CDJ95351.1 - 0.0017 18.4 0.0 0.0078 16.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CDJ95351.1 - 0.0025 17.2 0.1 0.029 13.7 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 CDJ95351.1 - 0.003 17.4 0.0 0.015 15.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 CDJ95351.1 - 0.018 14.7 0.3 0.3 10.7 0.1 2.4 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 CDJ95351.1 - 0.037 13.4 0.2 0.13 11.5 0.2 1.8 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family JmjC PF02373.22 CDJ95353.1 - 6e-24 84.7 0.1 1.2e-23 83.7 0.1 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CDJ95353.1 - 4.9e-19 69.0 0.8 3.5e-18 66.2 0.8 2.0 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 CDJ95353.1 - 0.02 14.6 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 Cupin domain IMUP PF15761.5 CDJ95353.1 - 0.1 13.3 5.7 0.22 12.2 5.7 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein Cupin_1 PF00190.22 CDJ95353.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Cupin UQ_con PF00179.26 CDJ95354.1 - 3.2e-46 156.5 0.0 3.7e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ95354.1 - 3e-05 23.7 0.0 3.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B ST7 PF04184.12 CDJ95355.1 - 1.5e-221 736.6 3.1 2.7e-221 735.7 3.1 1.4 1 1 0 1 1 1 1 ST7 protein TPR_14 PF13428.6 CDJ95355.1 - 0.00015 22.3 3.1 3.5 8.7 0.2 4.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ95355.1 - 0.00021 21.0 0.2 0.88 9.5 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ95355.1 - 0.0016 18.4 0.2 0.48 10.7 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ95355.1 - 0.0045 17.5 1.6 0.56 10.8 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ95355.1 - 0.012 16.2 0.3 0.093 13.4 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_S18 PF01084.20 CDJ95355.1 - 0.093 13.0 0.8 0.28 11.4 0.5 1.9 2 0 0 2 2 2 0 Ribosomal protein S18 Peptidase_M56 PF05569.11 CDJ95355.1 - 0.17 11.0 2.3 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 BlaR1 peptidase M56 Mon2_C PF16206.5 CDJ95356.1 - 2.8e-138 462.4 9.1 4.8e-135 451.7 9.1 4.1 1 1 0 1 1 1 1 C-terminal region of Mon2 protein DCB PF16213.5 CDJ95356.1 - 3.8e-57 192.8 6.2 3.8e-57 192.8 6.2 2.5 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 CDJ95356.1 - 3.7e-44 150.4 7.5 1.2e-42 145.6 0.0 3.5 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Asn_synthase PF00733.21 CDJ95356.1 - 4.8e-09 36.3 2.4 0.0066 16.2 0.1 3.3 2 1 0 3 3 3 3 Asparagine synthase DUF1981 PF09324.10 CDJ95356.1 - 0.00079 19.2 1.1 0.025 14.4 0.0 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) HEAT PF02985.22 CDJ95356.1 - 0.0025 17.9 0.4 3.6 8.1 0.1 4.1 2 0 0 2 2 2 1 HEAT repeat DUF3361 PF11841.8 CDJ95356.1 - 0.017 15.1 0.4 0.09 12.7 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) Pkinase PF00069.25 CDJ95357.1 - 1e-19 71.0 0.0 2.3e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ95357.1 - 1.5e-13 50.6 0.0 2.3e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ95357.1 - 0.078 12.9 0.0 1 9.3 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family COX14 PF14880.6 CDJ95358.1 - 0.093 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Adeno_E3_CR2 PF02439.15 CDJ95358.1 - 0.12 12.1 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ArAE_1_C PF11728.8 CDJ95359.1 - 0.17 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain RhoGEF PF00621.20 CDJ95360.1 - 6.2e-39 134.1 6.3 6.2e-39 134.1 6.3 1.9 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.29 CDJ95360.1 - 4.9e-13 49.5 0.0 4.6e-07 30.3 0.0 2.6 2 0 0 2 2 2 2 PH domain FYVE PF01363.21 CDJ95360.1 - 0.00045 20.3 12.3 0.00045 20.3 12.3 2.5 3 0 0 3 3 3 1 FYVE zinc finger IQ_SEC7_PH PF16453.5 CDJ95360.1 - 0.00073 19.5 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 PH domain C1_1 PF00130.22 CDJ95360.1 - 0.011 15.6 5.9 0.038 13.9 5.9 1.9 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PH_16 PF17838.1 CDJ95360.1 - 0.027 14.3 0.1 0.62 9.9 0.0 2.9 2 1 0 2 2 2 0 PH domain PH_13 PF16652.5 CDJ95360.1 - 0.039 13.8 0.3 0.039 13.8 0.3 4.0 3 2 1 4 4 4 0 Pleckstrin homology domain Sulfotransfer_4 PF17784.1 CDJ95360.1 - 0.058 13.2 0.6 0.26 11.1 0.3 2.2 2 0 0 2 2 2 0 Sulfotransferase domain fn3 PF00041.21 CDJ95361.1 - 1.1e-17 64.1 0.3 1.9e-05 24.9 0.0 3.1 3 0 0 3 3 3 3 Fibronectin type III domain T6_Ig_like PF18002.1 CDJ95361.1 - 0.07 13.0 0.1 0.17 11.8 0.1 1.6 2 0 0 2 2 2 0 T6 antigen Ig like domain RVT_1 PF00078.27 CDJ95362.1 - 2.7e-22 79.4 0.0 4e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDJ95362.1 - 8.9e-17 61.0 0.0 2.7e-16 59.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ95362.1 - 2.8e-07 30.7 0.0 5.9e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PhoU_div PF01865.16 CDJ95363.1 - 0.035 13.4 0.9 0.094 12.0 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function DUF47 Blo-t-5 PF11642.8 CDJ95363.1 - 0.078 13.0 3.5 0.13 12.2 1.2 2.4 2 0 0 2 2 2 0 Mite allergen Blo t 5 TINF2_N PF14973.6 CDJ95363.1 - 1.3 9.4 5.6 0.69 10.2 0.4 2.9 3 0 0 3 3 3 0 TERF1-interacting nuclear factor 2 N-terminus DUF5339 PF17274.2 CDJ95363.1 - 5 8.0 11.2 3.2 8.7 4.7 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5339) ABC_membrane PF00664.23 CDJ95364.1 - 4e-35 121.8 18.9 4e-35 121.8 18.9 2.0 2 1 1 3 3 3 1 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ95364.1 - 1.6e-23 83.8 0.1 3.2e-23 82.7 0.1 1.6 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 CDJ95364.1 - 2.4e-05 24.3 0.1 4.9e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 CDJ95364.1 - 0.0009 19.3 0.5 0.0022 18.1 0.5 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CDJ95364.1 - 0.01 16.3 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 CDJ95364.1 - 0.011 15.9 0.2 0.029 14.4 0.0 1.9 2 0 0 2 2 2 0 Dynamin family NB-ARC PF00931.22 CDJ95364.1 - 0.019 14.2 0.0 0.04 13.1 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 CDJ95364.1 - 0.022 14.5 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 CDJ95364.1 - 0.037 13.4 0.9 0.59 9.5 0.2 2.2 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_7 PF12775.7 CDJ95364.1 - 0.059 12.9 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP-synt_ab PF00006.25 CDJ95364.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_21 PF13304.6 CDJ95364.1 - 0.074 12.8 2.0 0.16 11.8 0.6 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_13 PF13166.6 CDJ95364.1 - 0.11 11.1 0.0 0.19 10.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATP1G1_PLM_MAT8 PF02038.16 CDJ95364.1 - 1.6 8.2 4.3 4.7 6.7 0.2 3.3 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family UvrA_DNA-bind PF17755.1 CDJ95365.1 - 0.05 14.0 0.1 0.064 13.6 0.1 1.2 1 0 0 1 1 1 0 UvrA DNA-binding domain Mit_KHE1 PF10173.9 CDJ95365.1 - 0.11 12.6 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related TT_ORF2 PF02957.15 CDJ95367.1 - 2.9 8.8 5.2 0.63 11.0 1.4 1.8 2 1 1 3 3 3 0 TT viral ORF2 Nop14 PF04147.12 CDJ95368.1 - 0.0006 18.2 31.8 0.00078 17.8 31.8 1.1 1 0 0 1 1 1 1 Nop14-like family DUF2457 PF10446.9 CDJ95368.1 - 0.00088 18.5 43.5 0.0015 17.8 43.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) SDA1 PF05285.12 CDJ95368.1 - 0.49 9.8 40.2 0.66 9.4 40.2 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 CDJ95368.1 - 1.3 8.3 39.3 1.7 7.9 39.3 1.1 1 0 0 1 1 1 0 BUD22 PNISR PF15996.5 CDJ95368.1 - 1.9 8.7 18.0 2.8 8.2 18.0 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR TFIIF_alpha PF05793.12 CDJ95368.1 - 4.6 5.7 48.8 8.5 4.8 48.8 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SLC12 PF03522.15 CDJ95368.1 - 7.1 5.5 9.3 8.9 5.2 9.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Homeodomain PF00046.29 CDJ95370.1 - 5.7e-22 77.3 3.9 1.2e-21 76.3 3.9 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ95370.1 - 0.00088 19.1 0.3 0.002 18.0 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 CDJ95370.1 - 0.013 14.9 0.3 0.025 14.1 0.3 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez YdaS_antitoxin PF15943.5 CDJ95370.1 - 0.05 13.5 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Enkurin PF13864.6 CDJ95370.1 - 0.42 11.1 2.7 0.69 10.4 2.7 1.4 1 0 0 1 1 1 0 Calmodulin-binding Gal-bind_lectin PF00337.22 CDJ95371.1 - 2e-28 98.6 0.0 2.5e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Galactoside-binding lectin DUF1080 PF06439.11 CDJ95371.1 - 0.18 11.9 0.1 2.5 8.2 0.0 2.1 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1080) Gal-bind_lectin PF00337.22 CDJ95372.1 - 2.1e-27 95.3 1.5 2.5e-27 95.0 1.5 1.1 1 0 0 1 1 1 1 Galactoside-binding lectin Gal-bind_lectin PF00337.22 CDJ95373.1 - 6.1e-17 61.4 0.1 7e-17 61.2 0.1 1.1 1 0 0 1 1 1 1 Galactoside-binding lectin Troponin PF00992.20 CDJ95375.1 - 4.6e-06 27.0 9.4 4.6e-06 27.0 9.4 2.4 2 1 0 2 2 2 1 Troponin DUF4795 PF16043.5 CDJ95375.1 - 0.011 15.4 5.9 0.027 14.1 3.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) GCN5L1 PF06320.13 CDJ95375.1 - 0.2 11.8 3.1 0.43 10.7 3.1 1.5 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Herpes_UL6 PF01763.16 CDJ95375.1 - 0.32 9.5 1.5 0.4 9.2 1.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like LMBR1 PF04791.16 CDJ95375.1 - 0.92 8.3 1.9 1.1 8.0 1.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein MutS_III PF05192.18 CDJ95376.1 - 2.2e-21 77.0 0.7 4e-21 76.1 0.7 1.3 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 CDJ95376.1 - 0.057 13.7 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 MutS domain II PVL_ORF50 PF07768.11 CDJ95378.1 - 1.3 9.3 6.0 2.8 8.3 6.0 1.6 1 0 0 1 1 1 0 PVL ORF-50-like family QIL1 PF15884.5 CDJ95379.1 - 6e-16 58.8 0.1 7.5e-16 58.5 0.1 1.1 1 0 0 1 1 1 1 MICOS complex subunit MIC13, QIL1 GntR PF00392.21 CDJ95379.1 - 0.11 12.1 0.0 0.27 10.9 0.0 1.6 1 1 1 2 2 2 0 Bacterial regulatory proteins, gntR family DUF768 PF05589.11 CDJ95383.1 - 0.088 12.8 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF768) Peptidase_S28 PF05577.12 CDJ95384.1 - 1.1e-169 564.9 0.1 6.9e-84 282.1 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 CDJ95384.1 - 1.4e-10 40.8 0.0 5.9e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ95384.1 - 1.1e-09 38.4 0.0 9.8e-05 22.1 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.20 CDJ95384.1 - 8.2e-07 28.9 0.0 4.1e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Putative esterase Peptidase_S9 PF00326.21 CDJ95384.1 - 7.2e-06 25.6 0.1 0.00027 20.5 0.0 2.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2920 PF11144.8 CDJ95384.1 - 0.002 17.4 0.0 1.2 8.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2920) TRIC PF05197.13 CDJ95386.1 - 2.1e-79 265.6 4.3 2.6e-79 265.3 4.3 1.1 1 0 0 1 1 1 1 TRIC channel TRIC PF05197.13 CDJ95387.1 - 2e-83 278.7 2.5 2.5e-83 278.4 2.5 1.1 1 0 0 1 1 1 1 TRIC channel DUF4239 PF14023.6 CDJ95387.1 - 1.8 8.2 4.6 0.9 9.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) AgrB PF04647.15 CDJ95387.1 - 3 7.1 6.8 0.45 9.8 0.7 2.1 2 0 0 2 2 2 0 Accessory gene regulator B CAF1 PF04857.20 CDJ95388.1 - 1e-67 228.6 0.0 5.5e-35 121.0 0.0 2.1 1 1 1 2 2 2 2 CAF1 family ribonuclease MutS_V PF00488.21 CDJ95389.1 - 5.3e-43 147.3 0.0 9.6e-43 146.4 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CDJ95389.1 - 5.1e-14 52.9 0.8 5.1e-14 52.9 0.8 2.2 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 CDJ95389.1 - 6.3e-09 36.1 0.0 1.5e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV T3SS_ATPase_C PF18269.1 CDJ95389.1 - 0.039 13.8 0.1 0.97 9.3 0.0 2.5 2 0 0 2 2 2 0 T3SS EscN ATPase C-terminal domain HTH_38 PF13936.6 CDJ95390.1 - 1.5e-05 24.7 0.2 7.5e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 CDJ95390.1 - 1.5e-05 25.1 0.5 2.7e-05 24.3 0.5 1.4 1 0 0 1 1 1 1 Transposase HTH_50 PF18024.1 CDJ95390.1 - 0.00032 20.2 0.1 0.00077 19.0 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_IS630 PF01710.16 CDJ95390.1 - 0.00044 20.3 0.1 0.00072 19.6 0.1 1.3 1 0 0 1 1 1 1 Transposase HTH_11 PF08279.12 CDJ95390.1 - 0.0025 17.7 0.1 0.0044 16.9 0.1 1.3 1 0 0 1 1 1 1 HTH domain HTH_23 PF13384.6 CDJ95390.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_32 PF13565.6 CDJ95390.1 - 0.016 15.9 0.1 0.3 11.7 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_40 PF14493.6 CDJ95390.1 - 0.026 15.0 0.1 0.039 14.4 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain IF2_N PF04760.15 CDJ95390.1 - 0.026 14.3 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Transposase_1 PF01359.18 CDJ95390.1 - 0.037 13.9 0.8 0.058 13.2 0.1 1.7 2 0 0 2 2 2 0 Transposase (partial DDE domain) TubC_N PF18563.1 CDJ95390.1 - 0.049 13.6 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 TubC N-terminal docking domain HTH_6 PF01418.17 CDJ95390.1 - 0.062 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_5 PF01022.20 CDJ95390.1 - 0.07 13.0 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_10 PF04967.12 CDJ95390.1 - 0.077 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain GerE PF00196.19 CDJ95390.1 - 0.2 11.2 0.2 0.35 10.4 0.2 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Sema PF01403.19 CDJ95391.1 - 0.00077 18.4 0.0 0.00096 18.1 0.0 1.1 1 0 0 1 1 1 1 Sema domain IFT57 PF10498.9 CDJ95392.1 - 0.0018 17.3 8.5 0.0018 17.3 8.5 2.6 2 1 0 2 2 2 1 Intra-flagellar transport protein 57 ANTAR PF03861.14 CDJ95392.1 - 0.041 13.7 0.0 0.14 12.0 0.0 1.9 1 0 0 1 1 1 0 ANTAR domain Speriolin_C PF15059.6 CDJ95392.1 - 0.29 11.3 3.2 1.7 8.7 0.0 2.5 2 0 0 2 2 2 0 Speriolin C-terminus Spectrin PF00435.21 CDJ95392.1 - 2.5 8.6 19.2 16 6.0 2.2 3.8 2 1 1 3 3 3 0 Spectrin repeat Cluap1 PF10234.9 CDJ95392.1 - 3.1 7.1 20.1 0.062 12.7 7.2 2.8 3 0 0 3 3 3 0 Clusterin-associated protein-1 DUF2524 PF10732.9 CDJ95392.1 - 3.3 8.1 12.1 0.67 10.3 2.4 4.1 4 1 0 4 4 4 0 Protein of unknown function (DUF2524) DUF16 PF01519.16 CDJ95392.1 - 8.1 7.0 16.0 10 6.7 2.5 3.8 2 1 1 3 3 3 0 Protein of unknown function DUF16 TMPIT PF07851.13 CDJ95392.1 - 8.6 5.5 20.2 0.11 11.7 9.4 2.7 1 1 1 3 3 3 0 TMPIT-like protein Snapin_Pallidin PF14712.6 CDJ95392.1 - 9.9 6.7 14.2 0.48 10.9 0.2 3.9 2 1 0 2 2 2 0 Snapin/Pallidin EB PF01683.18 CDJ95393.1 - 0.9 9.9 31.2 1.3 9.3 3.8 3.5 2 2 1 3 3 3 0 EB module PHR PF08005.12 CDJ95395.1 - 2.5e-62 210.0 0.0 3.7e-35 121.8 0.0 3.2 4 0 0 4 4 4 2 PHR domain RCC1 PF00415.18 CDJ95395.1 - 1e-23 83.7 11.4 9e-12 45.4 0.2 5.3 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ95395.1 - 4.1e-17 61.5 16.1 9.2e-08 31.7 2.7 4.9 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat zf-B_box PF00643.24 CDJ95395.1 - 1.3e-05 25.3 7.5 1.3e-05 25.3 7.5 4.6 3 0 0 3 3 3 1 B-box zinc finger zf-RING_2 PF13639.6 CDJ95395.1 - 0.0011 19.3 9.0 0.0011 19.3 9.0 7.3 7 1 0 7 7 7 1 Ring finger domain Filamin PF00630.19 CDJ95395.1 - 0.11 13.3 0.0 0.34 11.7 0.0 1.8 1 0 0 1 1 1 0 Filamin/ABP280 repeat Ribosomal_S5_C PF03719.15 CDJ95396.1 - 2e-18 65.6 0.0 4.1e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 CDJ95396.1 - 6.1e-15 55.0 0.7 1.2e-14 54.0 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain NLRC4_HD2 PF17776.1 CDJ95396.1 - 0.13 12.8 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 NLRC4 helical domain HD2 CAP PF00188.26 CDJ95397.1 - 4.8e-07 30.7 0.0 3.7e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ95397.1 - 0.016 15.5 3.3 0.079 13.2 3.3 1.9 1 1 0 1 1 1 0 Ancylostoma-associated secreted protein related Peptidase_M8 PF01457.16 CDJ95398.1 - 0.00027 19.8 0.6 0.00031 19.6 0.6 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 CDJ95399.1 - 1.1e-65 222.3 8.8 1.1e-65 222.3 8.8 1.4 2 0 0 2 2 2 1 Leishmanolysin Peptidase_M8 PF01457.16 CDJ95402.1 - 2.7e-54 184.8 5.0 5.5e-54 183.7 5.0 1.4 1 1 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 CDJ95403.1 - 3.1e-36 125.2 6.5 6.6e-27 94.4 6.3 2.1 2 0 0 2 2 2 2 Leishmanolysin Peptidase_M8 PF01457.16 CDJ95404.1 - 1.7e-56 192.0 5.5 2.9e-56 191.3 5.5 1.3 1 0 0 1 1 1 1 Leishmanolysin Branch PF02485.21 CDJ95407.1 - 1.8e-23 83.3 0.4 3.6e-23 82.4 0.0 1.6 2 0 0 2 2 2 1 Core-2/I-Branching enzyme Transposase_1 PF01359.18 CDJ95412.1 - 1.8e-07 30.9 0.2 1.5e-06 27.9 0.1 2.4 2 0 0 2 2 2 1 Transposase (partial DDE domain) HTH_26 PF13443.6 CDJ95412.1 - 0.0014 19.0 0.1 0.0045 17.4 0.1 1.9 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain HTH_IclR PF09339.10 CDJ95412.1 - 0.006 16.4 0.1 0.012 15.4 0.1 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 CDJ95412.1 - 0.019 14.8 0.1 0.047 13.6 0.1 1.6 1 0 0 1 1 1 0 MarR family CENP-B_N PF04218.13 CDJ95412.1 - 0.057 13.1 0.6 0.24 11.1 0.1 2.2 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_Tnp_ISL3 PF13542.6 CDJ95412.1 - 0.057 12.8 0.1 0.057 12.8 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.6 CDJ95412.1 - 0.067 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 CDJ95412.1 - 0.072 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix LacI PF00356.21 CDJ95412.1 - 0.085 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family HTH_48 PF17906.1 CDJ95412.1 - 0.11 12.6 0.2 0.27 11.4 0.2 1.7 1 0 0 1 1 1 0 HTH domain in Mos1 transposase HTH_38 PF13936.6 CDJ95412.1 - 0.21 11.4 4.8 3.6 7.4 0.4 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 CDJ95412.1 - 0.32 10.8 2.3 6.3 6.7 0.1 3.2 3 0 0 3 3 3 0 Homeodomain-like domain HTH_32 PF13565.6 CDJ95412.1 - 3.9 8.1 6.8 2.1 9.0 0.3 3.0 3 0 0 3 3 3 0 Homeodomain-like domain RT_RNaseH PF17917.1 CDJ95413.1 - 2.5e-32 111.3 0.0 8.1e-32 109.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ95413.1 - 7.6e-30 102.9 0.0 1.9e-29 101.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ95413.1 - 1.1e-28 100.2 0.1 2.1e-28 99.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDJ95413.1 - 1.8e-18 66.9 0.0 3.9e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ95413.1 - 3.6e-16 59.0 0.4 7.1e-16 58.1 0.4 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain BTB PF00651.31 CDJ95414.1 - 0.00038 20.7 0.0 0.00066 19.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DDE_Tnp_1_7 PF13843.6 CDJ95415.1 - 2e-24 86.5 0.0 2.4e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 TDP43_N PF18694.1 CDJ95416.1 - 1.1e-23 82.8 0.0 2.1e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain RRM_1 PF00076.22 CDJ95416.1 - 1.2e-13 50.7 1.9 3.4e-08 33.2 0.2 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 CDJ95416.1 - 0.12 12.6 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Sulfotransfer_1 PF00685.27 CDJ95417.1 - 8.5e-22 77.9 0.0 1e-21 77.7 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CDJ95417.1 - 2.3e-10 41.3 0.1 3.7e-09 37.3 0.1 2.1 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 CDJ95417.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 2 0 0 2 2 2 0 Sulfotransferase family Exo_endo_phos_2 PF14529.6 CDJ95418.1 - 0.0026 17.6 0.2 0.027 14.3 0.2 2.2 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ95418.1 - 0.016 14.7 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 CDJ95419.1 - 2.1e-10 40.5 0.0 2.6e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF148 PF02520.17 CDJ95420.1 - 1.5e-22 79.8 0.1 1.9e-22 79.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF148 NB-ARC PF00931.22 CDJ95420.1 - 0.024 13.8 0.1 0.028 13.6 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain Baculo_PEP_C PF04513.12 CDJ95420.1 - 0.1 12.7 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF148 PF02520.17 CDJ95421.1 - 2.1e-23 82.5 1.0 2.6e-23 82.2 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 NB-ARC PF00931.22 CDJ95421.1 - 0.0087 15.3 0.7 0.011 14.9 0.7 1.2 1 0 0 1 1 1 1 NB-ARC domain Baculo_PEP_C PF04513.12 CDJ95421.1 - 0.011 15.8 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus MAP65_ASE1 PF03999.12 CDJ95421.1 - 0.032 12.9 0.2 0.045 12.5 0.2 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF5304 PF17230.2 CDJ95421.1 - 0.083 13.1 0.2 0.12 12.6 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5304) SF-assemblin PF06705.11 CDJ95421.1 - 0.085 12.2 0.3 0.11 11.8 0.3 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin COG2 PF06148.11 CDJ95421.1 - 0.12 12.5 0.5 0.19 11.8 0.5 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Ribosomal_L3 PF00297.22 CDJ95422.1 - 1.1e-177 590.5 9.7 1.3e-177 590.3 9.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 RRM_1 PF00076.22 CDJ95423.1 - 7e-31 105.9 0.0 3e-14 52.6 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_92 PF07971.12 CDJ95423.1 - 0.0041 16.1 0.0 0.0075 15.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 92 Peptidase_C71 PF12386.8 CDJ95423.1 - 0.077 12.6 0.2 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei Annexin PF00191.20 CDJ95424.1 - 4.5e-96 314.9 6.9 4.8e-25 87.4 0.0 4.1 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.6 CDJ95424.1 - 0.08 13.4 0.5 7.4 7.1 0.1 3.2 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF2040 PF09745.9 CDJ95425.1 - 1.1e-30 106.2 25.2 1.1e-30 106.2 25.2 3.5 3 1 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) zf-rbx1 PF12678.7 CDJ95426.1 - 5.3e-08 33.0 2.7 1.1e-07 32.0 2.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CDJ95426.1 - 9.4e-07 29.1 4.5 8.8e-06 26.0 4.5 2.6 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CDJ95426.1 - 3e-05 23.9 3.6 6.8e-05 22.7 3.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDJ95426.1 - 0.00012 21.9 1.8 0.00056 19.7 2.0 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CDJ95426.1 - 0.00077 19.3 3.3 0.00077 19.3 3.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDJ95426.1 - 0.0016 18.2 0.4 0.0016 18.2 0.4 2.4 3 0 0 3 3 3 1 RING-like zinc finger zf-Di19 PF05605.12 CDJ95426.1 - 0.0019 18.5 2.0 0.4 11.0 0.2 2.8 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_17 PF17120.5 CDJ95426.1 - 0.0025 17.4 0.9 0.0025 17.4 0.9 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 CDJ95426.1 - 0.004 17.0 5.3 0.0043 16.8 0.6 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ95426.1 - 0.0055 16.7 1.9 0.056 13.5 1.9 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 CDJ95426.1 - 0.0095 16.0 2.5 0.0095 16.0 2.5 2.3 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 CDJ95426.1 - 0.026 14.7 6.6 1.8 8.8 6.6 3.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 CDJ95426.1 - 0.034 14.0 2.9 0.28 11.1 2.9 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 CDJ95426.1 - 0.1 12.7 0.1 0.26 11.4 0.1 1.7 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 CDJ95427.1 - 5.2e-11 42.2 5.1 7.4e-11 41.7 5.1 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ95427.1 - 1.2e-10 41.1 5.7 1.7e-10 40.6 5.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ95427.1 - 7.1e-10 39.1 8.3 9.9e-10 38.6 8.3 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ95427.1 - 6.9e-09 35.4 8.0 1.1e-08 34.8 8.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ95427.1 - 7.2e-08 32.3 4.5 1.1e-07 31.8 2.0 2.1 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CDJ95427.1 - 7.8e-08 32.1 5.9 1.1e-07 31.5 5.9 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CDJ95427.1 - 2.1e-06 27.6 4.8 3.2e-06 27.0 4.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CDJ95427.1 - 9.2e-06 25.6 1.6 1.4e-05 25.0 1.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CDJ95427.1 - 1.1e-05 25.6 4.8 2e-05 24.8 4.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 CDJ95427.1 - 0.00023 21.3 6.8 0.00041 20.4 6.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 CDJ95427.1 - 0.0015 18.4 2.3 0.0015 18.4 2.3 1.5 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.12 CDJ95427.1 - 0.0031 16.9 0.1 0.004 16.6 0.1 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger IBR PF01485.21 CDJ95427.1 - 0.013 15.8 6.6 0.11 12.8 2.2 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-UDP PF14569.6 CDJ95427.1 - 0.08 13.1 1.6 0.19 11.9 1.6 1.6 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 CDJ95427.1 - 0.13 12.1 4.6 0.29 11.0 4.6 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 CDJ95427.1 - 0.36 11.0 4.1 1.8 8.7 4.1 2.0 1 1 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 CDJ95427.1 - 1.1 9.0 6.2 2.4 7.8 6.3 1.5 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CDJ95427.1 - 1.2 9.0 8.6 0.1 12.4 3.5 1.9 2 0 0 2 2 2 0 RING-like zinc finger ODR4-like PF14778.6 CDJ95428.1 - 1.7e-51 175.3 0.1 2.1e-51 175.0 0.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 4-like KH_1 PF00013.29 CDJ95429.1 - 3.7e-16 58.7 0.8 1.9e-14 53.2 0.1 2.5 2 0 0 2 2 2 1 KH domain KH_4 PF13083.6 CDJ95429.1 - 0.00023 21.0 0.2 0.00046 20.0 0.2 1.4 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 CDJ95429.1 - 0.0097 15.7 0.4 0.021 14.6 0.4 1.6 1 0 0 1 1 1 1 KH domain HydF_dimer PF18128.1 CDJ95429.1 - 0.067 13.3 0.2 6.3 6.9 0.1 2.3 2 0 0 2 2 2 0 Hydrogen maturase F dimerization domain TFIIA PF03153.13 CDJ95429.1 - 9.3 6.1 13.2 13 5.7 13.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L11_N PF03946.14 CDJ95430.1 - 3.6e-24 84.4 0.1 7.4e-24 83.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CDJ95430.1 - 1.9e-21 76.3 0.1 5.2e-21 74.9 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain MCM PF00493.23 CDJ95431.1 - 8.5e-100 332.5 0.1 1.3e-99 331.9 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CDJ95431.1 - 2.6e-37 127.5 1.8 5.1e-37 126.5 1.8 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CDJ95431.1 - 5.2e-26 90.9 1.0 1.4e-25 89.5 1.0 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM6_C PF18263.1 CDJ95431.1 - 8.7e-24 83.8 6.7 9.4e-24 83.7 4.3 2.4 2 1 0 2 2 2 1 MCM6 C-terminal winged-helix domain Mg_chelatase PF01078.21 CDJ95431.1 - 2.7e-08 33.4 0.0 2.4e-07 30.4 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CDJ95431.1 - 9.1e-05 22.3 0.0 0.00024 21.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDJ95431.1 - 0.00013 22.0 0.0 0.00035 20.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM_N PF14551.6 CDJ95431.1 - 0.0017 18.9 0.7 0.0049 17.4 0.1 2.2 2 0 0 2 2 2 1 MCM N-terminal domain AAA_lid_7 PF17867.1 CDJ95431.1 - 0.008 16.4 0.1 0.023 14.9 0.1 1.7 1 0 0 1 1 1 1 Midasin AAA lid domain Sigma54_activat PF00158.26 CDJ95431.1 - 0.0089 15.7 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain YfkD PF14167.6 CDJ95431.1 - 0.014 14.6 0.0 0.1 11.8 0.0 2.1 2 0 0 2 2 2 0 YfkD-like protein Mg_chelatase_C PF13335.6 CDJ95431.1 - 0.34 11.6 2.5 1.4 9.6 1.6 2.5 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal TUG-UBL1 PF11470.8 CDJ95432.1 - 5.3e-15 55.4 0.4 2.2e-14 53.4 0.1 2.0 2 0 0 2 2 2 1 TUG ubiquitin-like domain Vps5 PF09325.10 CDJ95433.1 - 2.8e-67 226.7 13.5 3.8e-67 226.3 13.5 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 CDJ95433.1 - 4.2e-20 71.8 0.0 1e-19 70.6 0.0 1.7 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.9 CDJ95433.1 - 0.00011 21.7 1.5 0.0039 16.7 1.2 2.6 1 1 1 2 2 2 1 WASP-binding domain of Sorting nexin protein Pou PF00157.17 CDJ95433.1 - 0.028 14.4 0.5 5.7 7.0 0.2 2.6 2 0 0 2 2 2 0 Pou domain - N-terminal to homeobox domain Mustang PF15682.5 CDJ95433.1 - 0.094 12.8 0.1 0.32 11.1 0.1 1.9 1 0 0 1 1 1 0 Musculoskeletal, temporally activated-embryonic nuclear protein 1 eIF3_N PF09440.10 CDJ95433.1 - 0.12 12.8 2.3 0.23 11.9 0.3 2.3 1 1 0 2 2 2 0 eIF3 subunit 6 N terminal domain FlaC_arch PF05377.11 CDJ95433.1 - 0.14 12.6 0.1 4.6 7.7 0.0 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FAM92 PF06730.11 CDJ95433.1 - 0.16 11.4 5.0 0.046 13.1 1.7 1.7 2 0 0 2 2 2 0 FAM92 protein DUF2203 PF09969.9 CDJ95433.1 - 0.24 12.1 6.8 0.51 11.1 1.2 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Seryl_tRNA_N PF02403.22 CDJ95433.1 - 0.45 10.8 7.6 2.1 8.6 2.2 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Ras PF00071.22 CDJ95434.1 - 1.1e-35 122.6 0.1 1.3e-35 122.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ95434.1 - 2.5e-15 56.7 0.0 4.8e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ95434.1 - 1e-10 41.4 0.0 1.6e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDJ95434.1 - 6.3e-07 29.1 0.1 3.1e-06 26.9 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDJ95434.1 - 1e-05 25.6 0.0 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ95434.1 - 1.2e-05 25.3 0.0 0.0028 17.6 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase G-alpha PF00503.20 CDJ95434.1 - 0.014 14.6 0.1 0.36 9.9 0.0 2.1 1 1 0 2 2 2 0 G-protein alpha subunit Dynamin_N PF00350.23 CDJ95434.1 - 0.014 15.5 0.1 2.8 8.0 0.0 2.6 2 1 1 3 3 3 0 Dynamin family ImcF-related_N PF14331.6 CDJ95434.1 - 0.019 14.3 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 ImcF-related N-terminal domain AAA_14 PF13173.6 CDJ95434.1 - 0.023 14.8 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 CDJ95434.1 - 0.028 13.8 0.0 7.6 5.9 0.1 2.4 2 1 0 2 2 2 0 Bacterial TniB protein Thioredoxin_6 PF13848.6 CDJ95434.1 - 0.036 14.0 0.1 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like domain AAA_25 PF13481.6 CDJ95434.1 - 0.051 13.2 0.0 0.17 11.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain NOG1 PF06858.14 CDJ95434.1 - 0.086 12.6 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) FtsK_SpoIIIE PF01580.18 CDJ95434.1 - 0.12 11.7 0.3 3.4 7.0 0.0 2.4 2 1 1 3 3 3 0 FtsK/SpoIIIE family FAM176 PF14851.6 CDJ95435.1 - 0.06 13.0 0.0 0.06 13.0 0.0 2.3 2 0 0 2 2 2 0 FAM176 family ECSCR PF15820.5 CDJ95435.1 - 0.089 12.6 0.0 0.33 10.8 0.0 2.0 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator LapA_dom PF06305.11 CDJ95435.1 - 0.11 12.3 0.3 0.23 11.3 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF4064 PF13273.6 CDJ95435.1 - 0.12 12.7 1.8 0.35 11.2 1.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) MAP17 PF15807.5 CDJ95435.1 - 0.15 12.3 0.2 0.15 12.3 0.2 2.7 2 1 1 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Neur_chan_memb PF02932.16 CDJ95435.1 - 0.57 10.2 2.8 4 7.4 2.8 2.1 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LapA_dom PF06305.11 CDJ95436.1 - 6.7e-05 22.6 2.0 8.8e-05 22.2 2.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain TMEM154 PF15102.6 CDJ95436.1 - 0.0084 16.0 0.4 0.0091 15.9 0.4 1.1 1 0 0 1 1 1 1 TMEM154 protein family Syndecan PF01034.20 CDJ95436.1 - 0.011 15.6 1.0 0.018 14.9 1.0 1.5 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 CDJ95436.1 - 0.012 16.5 1.0 0.015 16.2 0.4 1.5 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Sarcoglycan_1 PF04790.13 CDJ95436.1 - 0.014 14.7 0.2 0.015 14.6 0.2 1.1 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein Holin_BhlA PF10960.8 CDJ95436.1 - 0.021 14.8 0.5 0.041 13.8 0.5 1.6 1 1 0 1 1 1 0 BhlA holin family DUF2615 PF11027.8 CDJ95436.1 - 0.03 14.5 0.1 0.044 13.9 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2615) SIT PF15330.6 CDJ95436.1 - 0.03 14.8 0.2 0.044 14.2 0.2 1.4 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF3742 PF12553.8 CDJ95436.1 - 0.034 14.3 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) DUF2681 PF10883.8 CDJ95436.1 - 0.035 14.5 0.2 0.047 14.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Rax2 PF12768.7 CDJ95436.1 - 0.043 13.3 0.2 0.044 13.2 0.2 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity FAM176 PF14851.6 CDJ95436.1 - 0.043 13.5 0.5 0.2 11.3 0.5 1.8 1 1 0 1 1 1 0 FAM176 family Tmemb_9 PF05434.11 CDJ95436.1 - 0.045 13.6 0.3 0.048 13.6 0.3 1.0 1 0 0 1 1 1 0 TMEM9 Halogen_Hydrol PF10112.9 CDJ95436.1 - 0.046 13.7 0.1 0.048 13.7 0.1 1.1 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF4834 PF16118.5 CDJ95436.1 - 0.063 14.2 0.3 0.09 13.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF4577 PF15145.6 CDJ95436.1 - 0.074 13.1 0.3 0.083 12.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) FixQ PF05545.11 CDJ95436.1 - 0.075 13.0 3.3 0.62 10.1 3.3 2.1 1 1 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF2207 PF09972.9 CDJ95436.1 - 0.089 11.5 0.1 0.093 11.5 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Cadherin_C_2 PF16492.5 CDJ95436.1 - 0.15 12.9 0.0 0.17 12.6 0.0 1.1 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal OAD_gamma PF04277.13 CDJ95436.1 - 0.21 12.2 3.1 0.69 10.5 3.1 1.8 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain NCU-G1 PF15065.6 CDJ95436.1 - 4.2 6.3 6.0 5.4 5.9 6.0 1.1 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 DUF4006 PF13179.6 CDJ95436.1 - 8.7 6.3 8.2 11 6.1 8.2 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF4006) FAD-oxidase_C PF02913.19 CDJ95438.1 - 1.4e-56 191.9 0.0 2e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CDJ95438.1 - 6.1e-35 120.0 0.0 1.1e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CDJ95438.1 - 0.068 13.3 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like Astacin PF01400.24 CDJ95439.1 - 1.6e-70 236.6 0.1 2.5e-70 236.0 0.1 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) ShK PF01549.24 CDJ95439.1 - 1.4e-17 63.9 21.8 1.2e-08 35.4 6.4 2.5 2 0 0 2 2 2 2 ShK domain-like Mucin PF01456.17 CDJ95439.1 - 0.019 14.9 31.9 0.038 14.0 31.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Peptidase_M10 PF00413.24 CDJ95439.1 - 0.077 12.8 0.8 3.4 7.5 0.1 2.8 3 0 0 3 3 3 0 Matrixin DNA_primase_lrg PF04104.14 CDJ95440.1 - 3.2e-79 266.1 0.2 8.6e-79 264.7 0.1 1.6 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit 7TM_GPCR_Srsx PF10320.9 CDJ95441.1 - 9.2e-06 25.2 0.7 1.3e-05 24.8 0.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2615 PF11027.8 CDJ95442.1 - 0.094 12.9 0.0 0.094 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) 7tm_1 PF00001.21 CDJ95443.1 - 0.0019 17.6 8.4 0.0027 17.1 8.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CPG4 PF15481.6 CDJ95444.1 - 4.8e-18 65.6 12.8 4.8e-18 65.6 12.8 1.7 2 0 0 2 2 2 1 Chondroitin proteoglycan 4 RNA_pol_L_2 PF13656.6 CDJ95446.1 - 0.086 12.6 0.2 4.2 7.2 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain UCH PF00443.29 CDJ95447.1 - 1.2e-39 136.4 0.4 2.4e-39 135.4 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CDJ95447.1 - 6.9e-14 51.9 1.3 1.4e-13 50.9 1.3 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 CDJ95447.1 - 2.9e-05 23.8 0.2 0.047 13.3 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 CDJ95447.1 - 0.061 13.1 0.8 0.25 11.1 1.1 1.9 2 0 0 2 2 2 0 Variant UBP zinc finger CbiG_C PF01890.16 CDJ95448.1 - 0.055 14.0 0.2 0.16 12.6 0.2 1.8 1 1 0 1 1 1 0 Cobalamin synthesis G C-terminus DUF4806 PF16064.5 CDJ95449.1 - 0.00022 21.5 0.0 0.0005 20.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4806) OSK PF17182.4 CDJ95449.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 OSK domain GreA_GreB_N PF03449.15 CDJ95449.1 - 0.64 10.2 4.3 0.28 11.4 0.5 2.1 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Myb_DNA-bind_5 PF13873.6 CDJ95450.1 - 0.015 15.4 0.2 0.04 14.0 0.2 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Lipase_GDSL_2 PF13472.6 CDJ95451.1 - 1.9e-10 41.4 0.0 3.2e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CDJ95451.1 - 0.002 18.1 0.1 0.7 9.8 0.0 2.2 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase Linker_histone PF00538.19 CDJ95452.1 - 1.5e-26 92.5 12.8 6.6e-22 77.7 0.1 3.5 3 0 0 3 3 3 2 linker histone H1 and H5 family UvrA_DNA-bind PF17755.1 CDJ95452.1 - 0.067 13.5 0.1 11 6.4 0.0 3.1 3 0 0 3 3 3 0 UvrA DNA-binding domain Ribosomal_L13 PF00572.18 CDJ95453.1 - 1.8e-09 37.9 1.2 2.8e-07 30.8 0.0 2.9 1 1 1 2 2 2 1 Ribosomal protein L13 QVR PF17064.5 CDJ95454.1 - 4.1e-06 26.9 7.0 0.00068 19.8 7.0 2.1 1 1 0 1 1 1 1 Sleepless protein DUF493 PF04359.14 CDJ95454.1 - 0.18 12.4 0.0 0.32 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF493) TIMP PF00965.17 CDJ95457.1 - 9.6e-05 22.3 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase TPR_10 PF13374.6 CDJ95458.1 - 2.5e-60 198.9 14.0 1.2e-13 50.4 0.0 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ95458.1 - 4.1e-58 193.6 17.3 8.7e-20 70.8 0.5 4.3 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ95458.1 - 7.6e-35 116.4 13.0 2.9e-06 26.9 0.1 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ95458.1 - 4.6e-30 102.2 29.7 2e-07 30.5 3.3 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ95458.1 - 5e-23 79.3 27.7 0.00015 21.6 2.2 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ95458.1 - 4.3e-18 64.0 26.0 0.002 18.2 1.3 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_MalT PF17874.1 CDJ95458.1 - 6.1e-16 58.7 1.8 2.7e-14 53.3 0.7 2.3 2 0 0 2 2 2 1 MalT-like TPR region TPR_16 PF13432.6 CDJ95458.1 - 1.1e-13 51.6 10.7 0.0011 19.5 0.1 5.6 3 2 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ95458.1 - 1.8e-12 46.9 10.1 0.94 10.5 0.0 6.5 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ95458.1 - 2.7e-12 47.0 11.5 4.6e-05 23.9 0.4 4.4 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ95458.1 - 4e-10 39.4 8.4 0.14 12.6 0.2 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 CDJ95458.1 - 1.9e-07 31.0 0.0 10 7.1 0.1 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ95458.1 - 6.8e-07 29.4 11.2 0.0081 16.4 0.2 4.3 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 CDJ95458.1 - 2.2e-06 27.5 1.5 0.012 15.8 0.0 5.2 6 0 0 6 6 5 1 PPR repeat ATG16 PF08614.11 CDJ95458.1 - 0.0008 19.7 4.8 0.0008 19.7 4.8 3.4 3 1 1 4 4 4 1 Autophagy protein 16 (ATG16) PPR_2 PF13041.6 CDJ95458.1 - 0.0075 16.4 2.0 0.81 9.9 0.0 3.4 4 0 0 4 4 2 1 PPR repeat family SHNi-TPR PF10516.9 CDJ95458.1 - 0.0086 15.5 5.5 0.75 9.3 0.2 4.4 4 0 0 4 4 4 1 SHNi-TPR TPR_3 PF07720.12 CDJ95458.1 - 0.011 15.7 15.5 0.61 10.1 0.8 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ95458.1 - 0.012 15.3 1.3 0.012 15.3 1.3 6.1 6 0 0 6 6 6 0 TPR repeat WbqC PF08889.11 CDJ95458.1 - 0.015 15.2 2.4 9.4 6.1 0.0 3.8 3 1 1 4 4 4 0 WbqC-like protein family DUF4919 PF16266.5 CDJ95458.1 - 0.051 13.5 1.1 0.33 10.9 0.1 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4919) MIT PF04212.18 CDJ95458.1 - 0.059 13.4 14.4 4.5 7.4 1.2 5.4 3 1 2 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 CDJ95458.1 - 0.062 13.6 7.6 8.7 6.8 0.6 4.6 3 2 3 6 6 6 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 CDJ95458.1 - 0.081 12.8 2.8 2 8.3 0.0 3.8 3 1 0 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal L27 PF02828.16 CDJ95458.1 - 0.11 12.2 0.3 0.49 10.2 0.0 2.4 2 0 0 2 2 1 0 L27 domain JIP_LZII PF16471.5 CDJ95458.1 - 0.13 12.4 2.9 0.4 10.9 2.9 1.9 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II Clathrin PF00637.20 CDJ95458.1 - 0.14 12.1 4.9 0.26 11.2 0.6 3.2 1 1 2 3 3 3 0 Region in Clathrin and VPS TMF_TATA_bd PF12325.8 CDJ95458.1 - 0.17 12.1 10.3 0.2 11.9 6.1 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding RPN6_N PF18055.1 CDJ95458.1 - 0.24 11.8 8.0 4.9 7.6 0.1 3.9 4 0 0 4 4 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain TSC22 PF01166.18 CDJ95458.1 - 0.26 11.6 3.2 11 6.4 0.5 2.9 1 1 1 2 2 2 0 TSC-22/dip/bun family RPN7 PF10602.9 CDJ95458.1 - 0.3 10.8 8.2 0.78 9.4 0.5 3.4 2 1 0 3 3 2 0 26S proteasome subunit RPN7 YfdX PF10938.8 CDJ95458.1 - 0.38 10.7 3.9 17 5.3 0.5 3.2 3 0 0 3 3 2 0 YfdX protein DUF627 PF04781.12 CDJ95458.1 - 0.41 10.7 8.2 20 5.3 0.1 4.5 4 1 1 5 5 4 0 Protein of unknown function (DUF627) TPR_6 PF13174.6 CDJ95458.1 - 1.5 9.7 18.5 3.5 8.5 0.3 5.2 6 0 0 6 6 4 0 Tetratricopeptide repeat Adaptin_N PF01602.20 CDJ95459.1 - 7.5e-130 433.9 7.7 8.6e-130 433.8 7.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CDJ95459.1 - 9.6e-10 38.7 0.5 9.4e-08 32.3 0.0 2.8 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDJ95459.1 - 0.00011 22.5 0.7 0.048 14.1 0.1 4.0 3 2 1 4 4 4 1 HEAT repeats DRIM PF07539.12 CDJ95459.1 - 0.0018 16.7 4.3 0.14 10.4 3.0 2.5 1 1 0 2 2 2 2 Down-regulated in metastasis HEAT PF02985.22 CDJ95459.1 - 0.0025 17.9 2.7 40 4.8 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat VPS28 PF03997.12 CDJ95459.1 - 0.0095 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 VPS28 protein Recep_L_domain PF01030.24 CDJ95461.1 - 2.7e-11 43.6 0.2 1.9e-06 28.0 0.1 2.3 2 0 0 2 2 2 2 Receptor L domain DiS_P_DiS PF06750.13 CDJ95461.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain Recep_L_domain PF01030.24 CDJ95462.1 - 2.7e-12 46.8 0.0 5.2e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Receptor L domain Shisa PF13908.6 CDJ95462.1 - 0.0046 17.2 0.6 0.0072 16.6 0.5 1.4 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator OAD_gamma PF04277.13 CDJ95462.1 - 0.016 15.8 0.2 0.04 14.5 0.2 1.7 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Man-6-P_recep PF02157.15 CDJ95462.1 - 0.068 12.2 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate receptor EphA2_TM PF14575.6 CDJ95462.1 - 0.1 13.5 0.1 0.22 12.4 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PRIMA1 PF16101.5 CDJ95462.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF4834 PF16118.5 CDJ95462.1 - 0.13 13.2 0.3 0.13 13.2 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) DUF1980 PF09323.10 CDJ95462.1 - 0.27 11.1 2.8 0.39 10.6 0.3 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1980) Baculo_11_kDa PF06143.11 CDJ95462.1 - 0.3 10.7 2.3 0.39 10.3 0.7 2.0 2 0 0 2 2 2 0 Baculovirus 11 kDa family TMEM154 PF15102.6 CDJ95462.1 - 0.82 9.6 9.3 3.7 7.4 9.3 2.1 1 1 0 1 1 1 0 TMEM154 protein family Recep_L_domain PF01030.24 CDJ95463.1 - 4.3e-13 49.4 0.2 1.5e-05 25.1 0.1 2.2 2 0 0 2 2 2 2 Receptor L domain RVT_1 PF00078.27 CDJ95465.1 - 2.5e-22 79.5 0.0 3.6e-11 43.0 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2703 PF10865.8 CDJ95465.1 - 0.0085 16.3 0.0 7.2 6.8 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF2703) Rsbr_N PF08678.10 CDJ95465.1 - 0.032 14.3 0.0 8.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Rsbr N terminal BPA_C PF18040.1 CDJ95465.1 - 0.052 13.5 0.0 17 5.4 0.0 2.5 2 0 0 2 2 2 0 beta porphyranase A C-terminal Exo_endo_phos_2 PF14529.6 CDJ95466.1 - 9.5e-07 28.7 0.0 2.2e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DivIC PF04977.15 CDJ95466.1 - 0.002 17.8 1.1 0.051 13.4 0.0 2.6 2 1 0 2 2 2 1 Septum formation initiator Motile_Sperm PF00635.26 CDJ95467.1 - 9.6e-06 25.4 0.0 2.4e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 MSP (Major sperm protein) domain APG6_N PF17675.1 CDJ95467.1 - 0.0012 19.4 12.8 0.0017 18.9 12.8 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region Sec34 PF04136.15 CDJ95467.1 - 0.029 14.3 2.3 0.06 13.2 2.3 1.5 1 0 0 1 1 1 0 Sec34-like family Cluap1 PF10234.9 CDJ95467.1 - 0.091 12.2 8.3 0.11 11.9 8.3 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Phage_GPO PF05929.11 CDJ95467.1 - 0.094 12.3 5.5 0.12 12.0 5.5 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase FapA PF03961.13 CDJ95467.1 - 0.23 10.0 5.1 0.28 9.8 5.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A RCC1 PF00415.18 CDJ95469.1 - 5.8e-46 154.9 8.5 9.5e-13 48.6 0.3 7.2 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ95469.1 - 1.2e-24 85.5 22.1 2.2e-05 24.1 0.2 6.1 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ95470.1 - 0.0014 18.3 4.1 0.44 10.4 0.1 2.6 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat DUF3253 PF11625.8 CDJ95470.1 - 0.048 13.9 0.5 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) UDPGT PF00201.18 CDJ95471.1 - 1.6e-05 23.9 0.1 1.8e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase HTH_Tnp_Tc3_1 PF11427.8 CDJ95471.1 - 0.038 13.8 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 Tc3 transposase PIG-U PF06728.13 CDJ95472.1 - 2.7e-07 30.0 0.0 4.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U PAS_11 PF14598.6 CDJ95473.1 - 4.9e-11 42.8 0.2 1.1e-07 31.9 0.0 3.4 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.12 CDJ95473.1 - 6.7e-11 42.3 0.0 0.00057 20.1 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 CDJ95473.1 - 2.7e-10 40.3 0.0 4.2e-09 36.4 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 CDJ95473.1 - 2.6e-06 27.6 0.0 1.3e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS_2 PF08446.11 CDJ95473.1 - 0.011 16.4 0.0 0.033 14.9 0.0 1.9 1 0 0 1 1 1 0 PAS fold PAS_4 PF08448.10 CDJ95473.1 - 0.016 15.4 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 PAS fold HLH PF00010.26 CDJ95473.1 - 0.018 15.0 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain KIP1 PF07765.12 CDJ95473.1 - 0.18 11.9 0.2 0.44 10.7 0.2 1.6 1 0 0 1 1 1 0 KIP1-like protein Astacin PF01400.24 CDJ95474.1 - 4.2e-46 157.0 0.8 5.4e-46 156.6 0.8 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) SMN PF06003.12 CDJ95475.1 - 1.3e-26 93.5 14.9 7.6e-12 45.0 2.1 3.0 1 1 2 3 3 3 3 Survival motor neuron protein (SMN) TUDOR PF00567.24 CDJ95475.1 - 2.5e-06 27.5 0.1 4e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Tudor domain Tudor-knot PF11717.8 CDJ95475.1 - 0.0024 17.7 0.1 0.0058 16.5 0.1 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF4537 PF15057.6 CDJ95475.1 - 0.019 15.0 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) DUF1325 PF07039.11 CDJ95475.1 - 0.031 14.4 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 SGF29 tudor-like domain Tudor_3 PF18115.1 CDJ95475.1 - 0.046 13.6 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain PWWP PF00855.17 CDJ95475.1 - 0.093 13.2 0.0 0.18 12.2 0.0 1.6 1 1 0 1 1 1 0 PWWP domain TspO_MBR PF03073.15 CDJ95476.1 - 1e-17 64.4 6.5 1.3e-17 64.1 6.5 1.1 1 0 0 1 1 1 1 TspO/MBR family UCH PF00443.29 CDJ95477.1 - 1.2e-34 120.0 0.0 3.1e-34 118.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ95477.1 - 5.1e-15 55.9 0.0 4.6e-12 46.2 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CDJ95477.1 - 1.4e-05 24.8 0.2 3.5e-05 23.5 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 CDJ95477.1 - 0.027 14.9 0.2 0.068 13.6 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain TBK1_ULD PF18396.1 CDJ95477.1 - 0.084 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain MORN PF02493.20 CDJ95478.1 - 1e-26 91.2 70.9 3.9e-05 23.3 1.2 8.8 9 0 0 9 9 9 8 MORN repeat Alanine_zipper PF11839.8 CDJ95478.1 - 0.011 16.1 14.5 0.041 14.2 14.5 2.0 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein SBP_bac_3 PF00497.20 CDJ95478.1 - 0.93 8.9 3.3 4.3 6.7 4.2 1.8 2 1 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 Taxilin PF09728.9 CDJ95479.1 - 8.6e-10 38.3 3.6 1.1e-09 38.0 3.6 1.0 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Lipoprotein_20 PF13942.6 CDJ95479.1 - 0.0048 16.8 0.7 0.0055 16.6 0.7 1.1 1 0 0 1 1 1 1 YfhG lipoprotein SlyX PF04102.12 CDJ95479.1 - 0.0095 16.5 0.3 0.012 16.2 0.3 1.2 1 0 0 1 1 1 1 SlyX DUF4315 PF14193.6 CDJ95479.1 - 0.054 13.5 3.9 0.081 12.9 3.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4315) Peptidase_A17 PF05380.13 CDJ95481.1 - 7.8e-40 136.5 0.6 2.2e-39 135.0 0.2 2.2 2 0 0 2 2 2 1 Pao retrotransposon peptidase DUF1759 PF03564.15 CDJ95481.1 - 1.2e-24 86.9 3.9 1.8e-24 86.3 0.6 3.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DUF5641 PF18701.1 CDJ95481.1 - 4e-16 58.9 1.1 1.5e-15 57.1 1.1 2.1 1 0 0 1 1 1 1 Family of unknown function (DUF5641) Integrase_H2C2 PF17921.1 CDJ95481.1 - 1.9e-12 47.1 1.7 1.9e-12 47.1 1.7 3.2 3 0 0 3 3 2 1 Integrase zinc binding domain rve PF00665.26 CDJ95481.1 - 4e-11 43.2 0.0 5.5e-10 39.5 0.0 2.7 3 0 0 3 3 2 1 Integrase core domain DUF1758 PF05585.12 CDJ95481.1 - 3.1e-10 40.1 0.0 1.1e-09 38.3 0.0 1.9 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 CDJ95481.1 - 4.9e-06 27.1 0.0 1.4e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 CDJ95481.1 - 8.3e-06 25.5 0.0 2.5e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CDJ95481.1 - 0.00024 21.6 0.0 0.0019 18.7 0.0 2.6 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 CDJ95481.1 - 0.00051 20.2 3.1 0.0014 18.8 3.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Peptidase_A2B PF12384.8 CDJ95481.1 - 0.0017 17.9 0.0 0.0038 16.8 0.0 1.6 1 0 0 1 1 1 1 Ty3 transposon peptidase RVP PF00077.20 CDJ95481.1 - 0.024 15.0 0.1 17 5.8 0.0 4.0 3 0 0 3 3 3 0 Retroviral aspartyl protease rve_3 PF13683.6 CDJ95481.1 - 0.035 13.9 0.1 0.29 10.9 0.0 2.8 2 0 0 2 2 1 0 Integrase core domain RVP_2 PF08284.11 CDJ95481.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF2682 PF10909.8 CDJ95481.1 - 0.076 13.5 0.1 1.3 9.5 0.1 3.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2682) DXP_synthase_N PF13292.6 CDJ95481.1 - 0.7 9.0 2.7 0.78 8.9 0.0 2.5 3 0 0 3 3 3 0 1-deoxy-D-xylulose-5-phosphate synthase Pox_Ag35 PF03286.14 CDJ95482.1 - 0.022 14.5 0.1 0.027 14.3 0.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF818 PF05677.12 CDJ95482.1 - 0.045 12.7 0.0 0.048 12.6 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Kinesin PF00225.23 CDJ95483.1 - 1.3e-106 356.4 0.0 1.3e-106 356.4 0.0 2.4 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ95483.1 - 1.7e-21 76.7 1.4 4.3e-21 75.4 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding TPR_MLP1_2 PF07926.12 CDJ95483.1 - 0.012 15.7 1.5 0.012 15.7 1.5 7.1 5 1 2 7 7 7 0 TPR/MLP1/MLP2-like protein DivIC PF04977.15 CDJ95483.1 - 0.073 12.9 0.3 0.073 12.9 0.3 9.1 7 2 3 10 10 10 0 Septum formation initiator Lectin_C_term PF18022.1 CDJ95483.1 - 0.11 13.0 0.8 0.34 11.4 0.1 2.2 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin C-terminal domain CAP_N PF01213.19 CDJ95484.1 - 0.15 11.5 1.2 0.16 11.4 1.2 1.0 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 CDJ95484.1 - 0.52 10.4 2.7 0.6 10.2 2.7 1.1 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Caskin-Pro-rich PF16907.5 CDJ95484.1 - 4.6 7.8 5.8 6 7.5 5.8 1.2 1 0 0 1 1 1 0 Proline rich region of Caskin proteins LRR_8 PF13855.6 CDJ95485.1 - 1.7e-28 98.2 19.8 5.2e-08 32.5 1.9 6.4 3 2 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 CDJ95485.1 - 1.1e-15 57.5 24.8 0.00019 21.7 1.8 7.4 4 2 3 8 8 8 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CDJ95485.1 - 6.1e-05 23.0 0.0 0.3 11.0 0.0 3.1 1 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 CDJ95485.1 - 0.024 15.1 20.0 36 5.5 0.1 8.9 7 3 1 8 8 8 0 Leucine Rich Repeat KKLCAg1 PF15204.6 CDJ95485.1 - 0.028 14.5 0.4 0.2 11.8 0.0 2.5 2 0 0 2 2 2 0 Kita-kyushu lung cancer antigen 1 DUF5383 PF17355.2 CDJ95485.1 - 0.042 14.2 0.0 0.092 13.1 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5383) LRR_9 PF14580.6 CDJ95485.1 - 0.083 12.4 5.8 18 4.8 0.1 3.9 2 1 2 4 4 4 0 Leucine-rich repeat LRR_6 PF13516.6 CDJ95485.1 - 0.093 12.8 23.8 45 4.5 0.7 9.2 10 0 0 10 10 10 0 Leucine Rich repeat DUF4834 PF16118.5 CDJ95485.1 - 0.11 13.4 0.0 0.27 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TMEM154 PF15102.6 CDJ95485.1 - 0.13 12.2 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family Ank_5 PF13857.6 CDJ95488.1 - 8.5e-14 51.4 0.1 1.2e-07 31.8 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ95488.1 - 3.6e-12 46.7 0.0 1e-07 32.4 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ95488.1 - 4e-08 33.7 0.0 0.0011 19.5 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CDJ95488.1 - 9.9e-08 32.1 0.0 0.0084 16.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CDJ95488.1 - 6e-07 29.3 0.0 0.07 13.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat TAF1_subA PF14929.6 CDJ95489.1 - 1.9e-06 27.5 1.6 8e-06 25.5 0.2 2.2 2 0 0 2 2 2 1 TAF RNA Polymerase I subunit A TPD52 PF04201.15 CDJ95490.1 - 2.7e-35 121.4 0.9 3.9e-35 120.8 0.9 1.2 1 0 0 1 1 1 1 Tumour protein D52 family Band_3_cyto PF07565.13 CDJ95490.1 - 0.003 17.4 0.4 0.0036 17.1 0.4 1.1 1 0 0 1 1 1 1 Band 3 cytoplasmic domain Myb_DNA-bind_5 PF13873.6 CDJ95490.1 - 0.055 13.5 4.1 0.15 12.2 0.1 2.4 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Sugar_tr PF00083.24 CDJ95491.1 - 0.0079 15.1 3.7 0.18 10.6 1.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter Wzy_C PF04932.15 CDJ95491.1 - 0.071 12.7 1.0 0.26 10.9 1.0 1.8 1 1 0 1 1 1 0 O-Antigen ligase CbtA PF09490.10 CDJ95491.1 - 0.099 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) DUF4516 PF14990.6 CDJ95491.1 - 0.13 12.0 0.2 0.34 10.7 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) 7TM_GPCR_Srt PF10321.9 CDJ95492.1 - 1.7e-13 50.3 4.0 1.9e-13 50.1 4.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt UNC-93 PF05978.16 CDJ95493.1 - 1.5e-43 148.3 12.2 1.7e-43 148.0 12.2 1.0 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 DNA_pol_A_exo1 PF01612.20 CDJ95494.1 - 1.1e-09 38.2 0.0 2.8e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 3'-5' exonuclease RVT_1 PF00078.27 CDJ95495.1 - 1.1e-05 25.1 0.0 2.4e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2315 PF10231.9 CDJ95495.1 - 0.037 14.1 0.1 0.25 11.5 0.0 2.3 2 0 0 2 2 2 0 Apoptogenic protein 1 NAM PF02365.15 CDJ95495.1 - 0.063 14.2 0.1 1.7 9.5 0.1 2.2 2 0 0 2 2 2 0 No apical meristem (NAM) protein Amidohydro_1 PF01979.20 CDJ95496.1 - 1.5e-10 40.9 0.0 2.5e-10 40.2 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CDJ95496.1 - 1e-06 28.6 0.2 2.1e-06 27.5 0.2 1.5 1 0 0 1 1 1 1 Amidohydrolase family Y_phosphatase PF00102.27 CDJ95498.1 - 8.7e-27 94.2 0.0 1.2e-26 93.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase bZIP_2 PF07716.15 CDJ95499.1 - 6.8e-08 32.5 16.3 1.1e-07 31.8 16.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CDJ95499.1 - 7.8e-05 22.7 14.4 0.00014 21.9 14.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 CDJ95499.1 - 0.00051 20.5 7.1 0.00091 19.7 7.1 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor GIT_CC PF16559.5 CDJ95499.1 - 0.021 14.7 0.6 0.046 13.6 0.6 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3391 PF11871.8 CDJ95499.1 - 6.8 7.2 8.4 14 6.2 7.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Fib_alpha PF08702.10 CDJ95499.1 - 7.6 6.7 6.9 9.7 6.4 5.2 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Laminin_G_2 PF02210.24 CDJ95500.1 - 6.1e-27 94.7 0.6 8e-19 68.5 0.0 2.7 3 0 0 3 3 3 2 Laminin G domain Laminin_G_1 PF00054.23 CDJ95500.1 - 1.6e-15 57.5 0.0 6.4e-12 45.8 0.0 2.3 2 0 0 2 2 2 2 Laminin G domain EGF PF00008.27 CDJ95500.1 - 0.00043 20.5 7.7 0.00095 19.4 7.7 1.6 1 0 0 1 1 1 1 EGF-like domain Polysacc_lyase PF14099.6 CDJ95500.1 - 0.0096 15.8 0.0 0.024 14.5 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide lyase Laminin_G_3 PF13385.6 CDJ95500.1 - 0.012 15.7 0.1 0.038 14.1 0.0 1.8 2 0 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily Glyco_hydro_65C PF03633.15 CDJ95500.1 - 0.16 11.9 0.1 0.42 10.5 0.1 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain Laminin_EGF PF00053.24 CDJ95500.1 - 0.19 11.9 8.9 0.45 10.7 8.9 1.5 1 0 0 1 1 1 0 Laminin EGF domain EGF_2 PF07974.13 CDJ95500.1 - 1.1 9.7 9.9 2.6 8.5 9.9 1.6 1 0 0 1 1 1 0 EGF-like domain DUF4736 PF15883.5 CDJ95501.1 - 0.13 11.9 2.3 0.1 12.3 0.4 1.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4736) Laminin_G_2 PF02210.24 CDJ95502.1 - 8e-10 39.4 2.0 8e-07 29.7 0.1 3.4 3 1 0 3 3 3 2 Laminin G domain Laminin_G_3 PF13385.6 CDJ95502.1 - 3.5e-07 30.5 4.3 9.7e-06 25.8 0.6 2.3 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Laminin_G_1 PF00054.23 CDJ95502.1 - 0.00013 22.2 0.2 0.0054 17.0 0.1 3.2 3 1 0 3 3 3 1 Laminin G domain hEGF PF12661.7 CDJ95502.1 - 0.0013 19.3 22.4 0.0015 19.1 6.9 3.3 2 1 0 2 2 2 2 Human growth factor-like EGF EGF PF00008.27 CDJ95502.1 - 0.0029 17.9 8.1 0.0029 17.9 8.1 2.7 2 0 0 2 2 2 1 EGF-like domain DUF4520 PF15016.6 CDJ95502.1 - 0.12 12.5 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) Syndecan PF01034.20 CDJ95502.1 - 0.19 11.7 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain LRR_4 PF12799.7 CDJ95503.1 - 2.1e-09 37.5 4.7 6.6e-05 23.2 0.7 3.1 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDJ95503.1 - 0.00056 19.4 0.2 0.00069 19.2 0.2 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 CDJ95503.1 - 0.012 15.3 1.6 0.042 13.6 0.9 2.1 1 1 1 2 2 2 0 Leucine rich repeat Pkinase PF00069.25 CDJ95504.1 - 9.5e-07 28.4 0.7 1.5e-06 27.8 0.7 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ95504.1 - 0.00089 18.6 0.4 0.0013 18.0 0.4 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_C1 PF00112.23 CDJ95504.1 - 0.14 12.2 0.1 0.25 11.4 0.1 1.3 1 0 0 1 1 1 0 Papain family cysteine protease tRNA-synt_His PF13393.6 CDJ95505.1 - 1.4e-31 109.9 0.0 4.1e-31 108.4 0.0 1.7 1 1 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 CDJ95505.1 - 4.9e-15 55.5 0.0 1.2e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 CDJ95505.1 - 2e-07 30.8 0.1 3.3e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs WHEP-TRS PF00458.20 CDJ95505.1 - 2.6e-06 27.5 7.3 1e-05 25.6 7.3 2.1 1 1 0 1 1 1 1 WHEP-TRS domain tRNA-synt_2b PF00587.25 CDJ95505.1 - 8.3e-05 22.6 0.0 0.00016 21.7 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 CDJ95505.1 - 0.00056 19.1 0.1 0.0081 15.3 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) adh_short PF00106.25 CDJ95506.1 - 1.5e-25 89.8 0.1 2.6e-25 89.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ95506.1 - 5.3e-18 65.4 0.2 8.8e-18 64.7 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RRM_1 PF00076.22 CDJ95506.1 - 4.8e-09 35.9 0.0 9.9e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_binding_10 PF13460.6 CDJ95506.1 - 1e-05 25.5 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding zf_CCCH_4 PF18345.1 CDJ95506.1 - 1.2e-05 25.2 2.0 1.2e-05 25.2 2.0 2.1 2 0 0 2 2 2 1 Zinc finger domain Torus PF16131.5 CDJ95506.1 - 2.9e-05 24.7 0.1 6.4e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Torus domain zf-CCCH_3 PF15663.5 CDJ95506.1 - 0.0065 16.7 0.3 0.016 15.4 0.3 1.6 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH PF00642.24 CDJ95506.1 - 0.01 15.7 3.3 0.01 15.7 3.3 2.2 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDJ95506.1 - 0.01 15.6 5.8 0.055 13.3 2.7 2.6 2 0 0 2 2 2 0 CCCH-type zinc finger FYVE PF01363.21 CDJ95506.1 - 0.047 13.8 0.5 0.047 13.8 0.5 1.8 2 0 0 2 2 1 0 FYVE zinc finger zf-CCCH_2 PF14608.6 CDJ95506.1 - 0.057 13.9 0.9 0.057 13.9 0.9 2.3 2 0 0 2 2 1 0 RNA-binding, Nab2-type zinc finger KR PF08659.10 CDJ95506.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 KR domain Nup35_RRM_2 PF14605.6 CDJ95506.1 - 0.075 13.1 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Polysacc_synt_2 PF02719.15 CDJ95506.1 - 0.13 11.3 0.1 0.21 10.7 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF836 PF05768.14 CDJ95506.1 - 0.59 10.6 2.2 37 4.8 0.1 2.7 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) AA_permease_2 PF13520.6 CDJ95508.1 - 6.2e-42 143.9 47.1 7.6e-42 143.6 47.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CDJ95508.1 - 4.2e-12 45.4 38.2 4.2e-12 45.4 38.2 1.5 1 1 0 1 1 1 1 Amino acid permease Orf78 PF06024.12 CDJ95508.1 - 0.31 11.3 0.0 0.31 11.3 0.0 3.4 3 1 1 4 4 4 0 Orf78 (ac78) Pex24p PF06398.11 CDJ95508.1 - 0.33 9.9 4.0 0.097 11.6 0.5 1.9 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin BRO1 PF03097.18 CDJ95509.1 - 2.6e-85 286.6 0.3 5.6e-85 285.5 0.3 1.5 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CDJ95509.1 - 2.1e-33 115.9 9.4 6.6e-33 114.3 9.4 1.8 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF1043 PF06295.12 CDJ95509.1 - 8.5 6.4 7.6 3.9 7.5 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) MRF_C2 PF13888.6 CDJ95510.1 - 2.7e-33 114.8 0.4 6.4e-33 113.6 0.4 1.7 1 0 0 1 1 1 1 Myelin gene regulatory factor C-terminal domain 2 NDT80_PhoG PF05224.12 CDJ95510.1 - 1.8e-23 83.7 1.6 2.9e-22 79.8 1.6 2.4 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family MRF_C1 PF13887.6 CDJ95510.1 - 6.8e-18 63.5 0.6 1.2e-17 62.8 0.6 1.4 1 0 0 1 1 1 1 Myelin gene regulatory factor -C-terminal domain 1 Peptidase_S74 PF13884.6 CDJ95510.1 - 7.7e-15 55.0 0.1 1.4e-14 54.1 0.1 1.5 1 0 0 1 1 1 1 Chaperone of endosialidase Fibrillin_U_N PF18193.1 CDJ95510.1 - 0.23 11.6 3.4 0.6 10.3 3.4 1.6 1 0 0 1 1 1 0 Fibrillin 1 unique N-terminal domain Thioredoxin PF00085.20 CDJ95511.1 - 1.7e-59 198.2 0.0 2.2e-28 98.2 0.0 2.5 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 CDJ95511.1 - 2.3e-09 37.4 0.0 9.6e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CDJ95511.1 - 1.3e-07 32.0 1.8 0.075 13.5 0.3 4.3 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CDJ95511.1 - 1.7e-05 25.1 0.0 0.38 11.1 0.0 3.7 3 2 2 5 5 5 2 Thioredoxin-like Thioredoxin_3 PF13192.6 CDJ95511.1 - 0.0004 20.4 0.0 0.41 10.7 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin domain OST3_OST6 PF04756.13 CDJ95511.1 - 0.00063 19.2 0.0 0.037 13.4 0.0 2.2 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 CDJ95511.1 - 0.0016 18.3 0.1 0.27 11.2 0.0 2.6 2 1 0 2 2 2 1 AhpC/TSA family Thioredoxin_4 PF13462.6 CDJ95511.1 - 0.011 15.9 0.1 4.1 7.5 0.0 2.5 2 1 0 2 2 2 0 Thioredoxin ERp29_N PF07912.13 CDJ95511.1 - 0.015 15.5 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 ERp29, N-terminal domain Thioredoxin_9 PF14595.6 CDJ95511.1 - 0.017 14.9 0.0 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_7 PF13899.6 CDJ95511.1 - 0.048 13.8 1.1 2.9 8.2 0.0 2.8 3 0 0 3 3 3 0 Thioredoxin-like Gal_Lectin PF02140.18 CDJ95511.1 - 0.11 13.0 0.1 0.22 12.0 0.1 1.4 1 0 0 1 1 1 0 Galactose binding lectin domain TMEM234 PF10639.9 CDJ95512.1 - 1.3e-33 115.4 2.2 1.6e-33 115.2 2.2 1.1 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 CDJ95512.1 - 6e-05 23.2 7.6 0.00038 20.6 7.6 2.0 1 1 0 1 1 1 1 EamA-like transporter family Orn_Arg_deC_N PF02784.16 CDJ95514.1 - 2.3e-36 125.4 0.0 3.1e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain LTD PF00932.19 CDJ95516.1 - 1.4e-13 51.2 0.0 1.5e-13 51.0 0.0 1.0 1 0 0 1 1 1 1 Lamin Tail Domain DSPc PF00782.20 CDJ95517.1 - 1.9e-35 121.6 0.0 2.7e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDJ95517.1 - 0.00032 20.4 0.0 0.00046 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CDJ95517.1 - 0.0033 17.5 0.0 0.0058 16.8 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPn PF14671.6 CDJ95517.1 - 0.093 13.2 0.2 0.26 11.7 0.2 1.7 1 1 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half DUF1233 PF06806.12 CDJ95517.1 - 0.16 11.5 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Putative excisionase (DUF1233) TSP_1 PF00090.19 CDJ95518.1 - 9e-20 70.6 58.8 8.3e-09 35.5 15.5 4.2 4 0 0 4 4 4 3 Thrombospondin type 1 domain CAP_N PF01213.19 CDJ95518.1 - 2.1 7.7 14.5 4 6.8 1.8 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 CDJ95518.1 - 9.6 6.2 9.9 1.4 8.9 0.7 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator C2 PF00168.30 CDJ95519.1 - 3.6e-60 200.7 1.4 2.5e-21 75.9 0.1 3.5 3 0 0 3 3 3 3 C2 domain DUF639 PF04842.12 CDJ95519.1 - 9.3e-05 22.0 1.7 0.0002 20.9 1.7 1.5 1 0 0 1 1 1 1 Plant protein of unknown function (DUF639) 2OG-FeII_Oxy_4 PF13661.6 CDJ95519.1 - 0.023 15.3 0.0 0.071 13.8 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF4253 PF14062.6 CDJ95519.1 - 0.059 13.6 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) PRT_C PF08372.10 CDJ95519.1 - 0.26 11.0 2.1 0.28 10.9 0.4 1.8 1 1 1 2 2 2 0 Plant phosphoribosyltransferase C-terminal BPD_transp_2 PF02653.16 CDJ95520.1 - 0.074 12.2 7.7 0.081 12.1 7.7 1.2 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component Pro_isomerase PF00160.21 CDJ95521.1 - 5e-48 163.4 0.1 5e-48 163.4 0.1 3.2 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FAM92 PF06730.11 CDJ95522.1 - 4.7e-11 42.5 10.2 12 5.2 0.0 11.7 3 1 10 14 14 14 8 FAM92 protein STOP PF05217.12 CDJ95522.1 - 7.6e-05 22.9 4.6 0.00041 20.6 4.6 2.4 1 0 0 1 1 1 1 STOP protein zf_CCCH_4 PF18345.1 CDJ95525.1 - 0.00083 19.3 4.7 0.074 13.1 0.0 2.9 2 1 0 2 2 2 2 Zinc finger domain Torus PF16131.5 CDJ95525.1 - 0.0016 19.1 5.6 0.026 15.2 0.2 2.2 1 1 1 2 2 2 2 Torus domain zf-CCCH PF00642.24 CDJ95525.1 - 0.0047 16.8 11.2 0.0093 15.9 0.2 3.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CLIP_SPH_mas PF18398.1 CDJ95525.1 - 7.7 7.0 7.5 0.63 10.5 1.6 2.1 2 0 0 2 2 2 0 Clip-domain serine protease homolog masquerade Transposase_1 PF01359.18 CDJ95526.1 - 5.1e-12 45.5 0.0 1.1e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 CDJ95527.1 - 4e-05 23.4 0.0 6.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease CIDE-N PF02017.15 CDJ95527.1 - 0.15 12.1 0.0 0.55 10.3 0.0 1.9 1 1 0 1 1 1 0 CIDE-N domain zf_CCCH_5 PF18384.1 CDJ95528.1 - 2.2e-21 75.7 13.0 2.9e-21 75.3 13.0 1.2 1 0 0 1 1 1 1 Unkempt Zinc finger domain 1 (Znf1) Gaa1 PF04114.14 CDJ95529.1 - 2.1e-63 215.1 4.8 5.5e-50 170.8 0.0 2.0 1 1 1 2 2 2 2 Gaa1-like, GPI transamidase component RVT_1 PF00078.27 CDJ95530.1 - 9.8e-21 74.3 0.0 1.9e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DivIC PF04977.15 CDJ95530.1 - 0.01 15.6 2.7 0.085 12.6 0.0 2.8 3 0 0 3 3 3 0 Septum formation initiator PhoQ_Sensor PF08918.10 CDJ95530.1 - 0.17 11.7 0.6 0.59 9.9 0.0 2.1 2 0 0 2 2 2 0 PhoQ Sensor RT_RNaseH PF17917.1 CDJ95530.1 - 0.48 10.7 4.4 0.45 10.8 0.4 3.1 5 0 0 5 5 5 0 RNase H-like domain found in reverse transcriptase Ion_trans PF00520.31 CDJ95532.1 - 5e-26 91.4 10.5 1.4e-20 73.5 8.0 2.1 1 1 1 2 2 2 2 Ion transport protein BTB_2 PF02214.22 CDJ95532.1 - 8.9e-12 45.2 0.0 2.1e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 CDJ95532.1 - 0.00088 19.2 0.9 0.00088 19.2 0.9 2.5 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.12 CDJ95532.1 - 0.021 13.5 8.0 0.33 9.6 0.2 2.2 1 1 1 2 2 2 0 Polycystin cation channel DUF4190 PF13828.6 CDJ95532.1 - 0.47 10.2 5.3 5.7 6.8 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) HLH PF00010.26 CDJ95534.1 - 1.8e-10 40.6 0.9 6e-10 38.9 0.2 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain COE1_HLH PF16423.5 CDJ95534.1 - 6e-05 22.7 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Transcription factor COE1 helix-loop-helix domain KIF1B PF12423.8 CDJ95534.1 - 0.0018 18.7 0.0 0.0038 17.6 0.0 1.6 1 0 0 1 1 1 1 Kinesin protein 1B Cep57_CLD PF14073.6 CDJ95534.1 - 0.035 14.1 4.9 0.059 13.4 4.9 1.4 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 TFIIA PF03153.13 CDJ95534.1 - 0.54 10.2 7.4 0.61 10.0 7.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lzipper-MIP1 PF14389.6 CDJ95534.1 - 1.3 9.4 8.6 0.14 12.5 2.6 2.5 3 1 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 ELO PF01151.18 CDJ95535.1 - 1.6e-54 185.0 27.4 1.9e-54 184.9 27.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family LPD24 PF18839.1 CDJ95535.1 - 0.1 12.9 4.7 0.19 12.0 4.7 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 24 SAC3_GANP PF03399.16 CDJ95536.1 - 9e-39 133.6 0.7 1.2e-38 133.2 0.7 1.1 1 0 0 1 1 1 1 SAC3/GANP family WD40 PF00400.32 CDJ95536.1 - 2.8e-05 24.8 11.7 0.013 16.3 0.3 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ95536.1 - 8.9e-05 22.7 0.6 0.027 14.8 0.1 3.6 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain SSF PF00474.17 CDJ95537.1 - 4.1e-33 114.8 26.3 8.1e-33 113.9 26.3 1.5 1 1 0 1 1 1 1 Sodium:solute symporter family Gpi1 PF05024.15 CDJ95537.1 - 7.6 6.6 11.6 0.13 12.3 2.8 2.2 2 0 0 2 2 2 0 N-acetylglucosaminyl transferase component (Gpi1) Pkinase PF00069.25 CDJ95538.1 - 3.2e-61 207.0 0.0 4.5e-61 206.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ95538.1 - 6.1e-30 104.4 0.1 9e-30 103.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ95538.1 - 0.00012 21.6 0.3 0.00018 21.0 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ95538.1 - 0.00061 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CDJ95538.1 - 0.0019 17.6 0.3 0.0053 16.1 0.3 1.8 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CDJ95538.1 - 0.018 14.6 0.2 0.029 14.0 0.2 1.3 1 0 0 1 1 1 0 RIO1 family zf-HC5HC2H PF13771.6 CDJ95539.1 - 3e-14 53.0 6.7 3e-14 53.0 6.7 3.8 4 0 0 4 4 4 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CDJ95539.1 - 2e-07 31.2 4.3 2e-07 31.2 4.3 3.4 3 1 1 4 4 4 1 PHD-zinc-finger like domain TPR_2 PF07719.17 CDJ95540.1 - 3.1e-22 76.8 9.2 0.00058 19.8 0.2 7.1 6 1 1 7 7 7 6 Tetratricopeptide repeat DnaJ PF00226.31 CDJ95540.1 - 1.7e-21 76.1 7.1 3.4e-21 75.1 3.0 3.0 2 0 0 2 2 2 1 DnaJ domain TPR_1 PF00515.28 CDJ95540.1 - 4.1e-21 73.8 6.3 0.00029 20.5 0.0 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ95540.1 - 1.6e-13 50.2 2.2 0.18 12.7 0.0 6.3 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ95540.1 - 2e-11 44.2 7.3 0.046 14.2 0.1 5.4 4 2 3 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ95540.1 - 3.1e-11 43.7 0.2 0.0021 18.7 0.4 5.1 2 2 2 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ95540.1 - 4.8e-11 42.8 8.5 0.00044 20.5 0.1 5.3 3 3 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ95540.1 - 1.5e-09 37.5 3.1 0.0013 19.0 0.0 6.1 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ95540.1 - 4.2e-09 36.4 6.2 0.12 12.6 0.1 4.6 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ95540.1 - 8.8e-09 34.9 13.3 0.3 11.4 0.1 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ95540.1 - 7.7e-08 32.5 8.0 0.14 12.4 0.7 4.9 2 2 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CDJ95540.1 - 8.1e-05 22.2 2.4 26 4.6 0.0 5.7 4 2 2 6 6 6 0 TPR repeat TPR_21 PF09976.9 CDJ95540.1 - 0.00016 21.5 8.1 5.3 6.7 0.0 4.4 2 2 2 4 4 4 1 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 CDJ95540.1 - 0.0002 21.8 8.6 26 5.7 0.0 7.6 8 1 1 9 9 8 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ95540.1 - 0.0014 18.4 4.6 2.8 7.9 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 CDJ95540.1 - 0.0034 17.7 9.6 0.037 14.4 0.6 4.1 4 1 0 4 4 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 CDJ95540.1 - 0.012 15.1 0.1 0.058 12.9 0.1 2.2 2 0 0 2 2 1 0 SHNi-TPR TPR_7 PF13176.6 CDJ95540.1 - 0.037 14.1 2.1 41 4.5 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 CDJ95540.1 - 0.074 13.7 0.0 1.6 9.6 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF357 PF04010.13 CDJ95540.1 - 0.14 12.2 2.0 2.1 8.4 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF357) CDC24 PF06395.11 CDJ95540.1 - 0.17 12.1 0.3 4.2 7.7 0.0 2.9 3 0 0 3 3 3 0 CDC24 Calponin YfdX PF10938.8 CDJ95540.1 - 0.22 11.4 6.7 0.42 10.5 0.1 3.4 2 1 0 3 3 3 0 YfdX protein SMBP PF16785.5 CDJ95540.1 - 0.24 11.6 6.3 3.8 7.8 0.9 3.4 3 1 1 4 4 3 0 Small metal-binding protein DUF4398 PF14346.6 CDJ95540.1 - 0.34 11.5 6.2 2.4 8.9 0.2 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) Alkyl_sulf_dimr PF14863.6 CDJ95540.1 - 0.82 10.1 4.9 1.7 9.1 0.2 3.0 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation DUF1771 PF08590.10 CDJ95540.1 - 1.3 9.4 10.8 0.76 10.2 0.1 3.3 3 0 0 3 3 2 0 Domain of unknown function (DUF1771) RVT_1 PF00078.27 CDJ95541.1 - 4.5e-08 32.9 0.0 5.2e-08 32.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LBP_BPI_CETP PF01273.25 CDJ95543.1 - 0.00045 19.9 0.0 0.002 17.7 0.0 2.0 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain Sel1 PF08238.12 CDJ95544.1 - 7.9e-10 39.1 4.0 0.22 12.2 0.1 5.6 6 0 0 6 6 6 4 Sel1 repeat TPR_3 PF07720.12 CDJ95544.1 - 0.091 12.8 0.4 0.41 10.7 0.4 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3970 PF13113.6 CDJ95544.1 - 1.9 8.8 5.5 5.9 7.2 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3970) UBA PF00627.31 CDJ95545.1 - 2.1e-24 85.0 0.6 3.9e-13 49.0 0.0 2.9 2 1 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 CDJ95545.1 - 4.5e-21 74.3 9.2 9.5e-21 73.3 9.2 1.6 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 CDJ95545.1 - 3.7e-13 49.0 0.1 6.3e-13 48.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rib_recp_KP_reg PF05104.12 CDJ95545.1 - 0.0021 19.1 15.0 0.0045 18.0 15.0 1.6 1 0 0 1 1 1 1 Ribosome receptor lysine/proline rich region Rad60-SLD_2 PF13881.6 CDJ95545.1 - 0.011 15.8 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF1421 PF07223.11 CDJ95545.1 - 0.026 14.4 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 UBA-like domain (DUF1421) DUF2407 PF10302.9 CDJ95545.1 - 0.038 14.6 0.0 0.066 13.8 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain CUE PF02845.16 CDJ95545.1 - 0.046 13.4 0.0 4.3 7.2 0.0 2.7 2 0 0 2 2 2 0 CUE domain HBS1_N PF08938.10 CDJ95545.1 - 0.09 13.1 0.2 14 6.1 0.0 3.0 2 1 1 3 3 3 0 HBS1 N-terminus SOG2 PF10428.9 CDJ95545.1 - 0.11 11.6 1.9 0.13 11.5 1.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Ubiquitin_5 PF18037.1 CDJ95545.1 - 0.11 12.8 0.1 0.18 12.2 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD PF11976.8 CDJ95545.1 - 0.12 12.3 0.3 0.18 11.6 0.3 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF3306 PF11748.8 CDJ95545.1 - 3.2 8.7 9.2 2.5 9.0 6.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3306) RHH_1 PF01402.21 CDJ95546.1 - 3.9e-05 23.4 0.1 0.42 10.6 0.0 2.9 2 0 0 2 2 2 2 Ribbon-helix-helix protein, copG family RhoGAP PF00620.27 CDJ95546.1 - 0.055 13.3 0.6 0.14 11.9 0.1 1.9 2 0 0 2 2 2 0 RhoGAP domain CagY_I PF14585.6 CDJ95546.1 - 0.14 12.3 0.1 0.33 11.1 0.1 1.6 1 0 0 1 1 1 0 CagY type 1 repeat Bestrophin PF01062.21 CDJ95548.1 - 4.8e-16 59.0 0.1 5.4e-16 58.8 0.1 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Bestrophin PF01062.21 CDJ95549.1 - 3.9e-21 75.7 0.2 4.8e-21 75.4 0.2 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Copine PF07002.16 CDJ95550.1 - 1.2e-57 194.9 0.0 1.8e-57 194.3 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 CDJ95550.1 - 5.1e-06 26.7 0.0 0.00072 19.8 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 CDJ95550.1 - 0.093 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 vWA found in TerF C terminus Peptidase_M16 PF00675.20 CDJ95551.1 - 1.1e-51 174.7 0.1 1.7e-51 174.1 0.1 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CDJ95551.1 - 4.8e-35 121.2 0.0 2.7e-32 112.3 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain DUF725 PF05267.12 CDJ95551.1 - 0.0053 16.7 0.2 0.012 15.6 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF725) DUF240 PF03086.14 CDJ95551.1 - 0.17 11.8 0.4 0.37 10.7 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF240) Ion_trans_2 PF07885.16 CDJ95552.1 - 4.2e-34 116.4 16.7 2.1e-18 66.0 2.9 2.2 2 0 0 2 2 2 2 Ion channel Astacin PF01400.24 CDJ95553.1 - 8.5e-66 221.2 0.3 1e-65 220.9 0.3 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 CDJ95553.1 - 2.2 8.1 6.6 39 4.0 2.1 2.9 1 1 2 3 3 3 0 Matrixin Frag1 PF10277.9 CDJ95554.1 - 5.5e-29 101.3 15.3 6.6e-29 101.0 15.3 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family E1_dh PF00676.20 CDJ95555.1 - 1.6e-71 240.8 0.0 2.3e-71 240.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 CDJ95555.1 - 4.7e-68 228.4 0.0 7.4e-68 227.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 CDJ95555.1 - 2.4e-52 176.7 0.0 4.5e-52 175.8 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 CDJ95555.1 - 8.5e-18 63.7 0.8 8.5e-18 63.7 0.8 3.2 3 0 0 3 3 3 1 2-oxoglutarate dehydrogenase N-terminus R2K_2 PF18299.1 CDJ95555.1 - 0.031 14.1 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain, R2K clade family 2 RepB PF07506.11 CDJ95555.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 RepB plasmid partitioning protein E1_dh PF00676.20 CDJ95556.1 - 7e-72 241.9 0.0 1e-71 241.4 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 CDJ95556.1 - 1.4e-66 223.5 0.0 2.1e-66 223.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 CDJ95556.1 - 4.1e-53 179.2 0.0 7.5e-53 178.3 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 CDJ95556.1 - 1.4e-18 66.2 7.3 4.4e-18 64.6 0.5 3.3 3 0 0 3 3 3 1 2-oxoglutarate dehydrogenase N-terminus R2K_2 PF18299.1 CDJ95556.1 - 0.017 15.0 0.0 0.05 13.5 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain, R2K clade family 2 ShK PF01549.24 CDJ95557.1 - 2.8e-19 69.4 28.6 5.2e-10 39.7 11.2 2.2 2 0 0 2 2 2 2 ShK domain-like Med3 PF11593.8 CDJ95557.1 - 4.1 6.5 10.4 5.2 6.1 10.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FSA_C PF10479.9 CDJ95557.1 - 5.1 5.1 7.7 6.2 4.8 7.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Ank_2 PF12796.7 CDJ95561.1 - 2.5e-64 213.8 21.7 1.9e-12 47.6 0.1 8.6 1 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ95561.1 - 1e-51 172.7 19.6 4e-08 33.7 0.0 11.2 3 3 10 13 13 13 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ95561.1 - 3.4e-41 134.5 17.3 0.0099 16.3 0.0 14.8 16 0 0 16 16 16 10 Ankyrin repeat Ank_5 PF13857.6 CDJ95561.1 - 7.4e-33 112.2 25.5 1.4e-07 31.6 0.1 11.3 4 3 9 13 13 13 9 Ankyrin repeats (many copies) Ank PF00023.30 CDJ95561.1 - 1.7e-29 100.9 29.3 0.0017 18.7 0.0 14.3 15 0 0 15 15 15 8 Ankyrin repeat DUF3718 PF12514.8 CDJ95561.1 - 0.14 12.3 0.1 5.3 7.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3718) 3HCDH_RFF PF18321.1 CDJ95561.1 - 0.94 10.0 7.2 20 5.7 0.0 4.9 4 1 0 4 4 4 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain BET PF17035.5 CDJ95562.1 - 0.0012 19.0 0.0 8.4 6.6 0.0 3.5 3 0 0 3 3 3 2 Bromodomain extra-terminal - transcription regulation AGA2 PF17366.2 CDJ95562.1 - 0.042 13.6 3.7 15 5.4 0.1 3.8 3 0 0 3 3 3 0 A-agglutinin-binding subunit Aga2 ShK PF01549.24 CDJ95562.1 - 4.8 7.8 7.2 46 4.7 0.3 5.5 3 0 0 3 3 3 0 ShK domain-like DUF1700 PF08006.11 CDJ95563.1 - 0.24 10.9 4.4 0.28 10.7 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) RVT_1 PF00078.27 CDJ95565.1 - 9e-26 90.8 0.0 1.2e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CENP-F_leu_zip PF10473.9 CDJ95566.1 - 0.0086 16.1 16.8 0.0086 16.1 16.8 7.2 5 2 2 8 8 8 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KASH_CCD PF14662.6 CDJ95566.1 - 0.014 15.2 0.1 0.014 15.2 0.1 5.3 2 1 3 5 5 5 0 Coiled-coil region of CCDC155 or KASH PKcGMP_CC PF16808.5 CDJ95566.1 - 0.044 13.6 0.7 0.044 13.6 0.7 4.5 4 1 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase MHC_I PF00129.18 CDJ95566.1 - 0.06 12.9 0.8 0.13 11.8 0.8 1.5 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 GSIII_N PF12437.8 CDJ95566.1 - 0.11 12.2 0.0 0.41 10.3 0.0 2.0 1 0 0 1 1 1 0 Glutamine synthetase type III N terminal DUF4951 PF16309.5 CDJ95566.1 - 0.13 12.3 0.0 0.51 10.4 0.0 2.0 1 0 0 1 1 1 0 Domian of unknown function (DUF4951) ApbA_C PF08546.11 CDJ95566.1 - 0.19 11.9 2.9 0.29 11.3 0.2 2.6 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal DUF2935 PF11155.8 CDJ95566.1 - 0.21 11.9 2.8 5 7.5 0.0 4.2 3 1 0 3 3 3 0 Domain of unknown function (DUF2935) Cas_DxTHG PF09455.10 CDJ95566.1 - 3 7.3 8.4 2.6 7.6 5.2 2.5 1 1 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family DDR PF08841.10 CDJ95567.1 - 0.1 11.6 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain ArsC PF03960.15 CDJ95567.1 - 0.12 12.4 0.1 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 ArsC family RVT_1 PF00078.27 CDJ95568.1 - 3.7e-42 144.3 0.1 8.5e-37 126.8 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) MYT1 PF08474.11 CDJ95568.1 - 0.092 12.7 0.1 17 5.2 0.0 2.2 2 0 0 2 2 2 0 Myelin transcription factor 1 DUF4488 PF14869.6 CDJ95568.1 - 0.15 12.0 0.5 22 5.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4488) TB2_DP1_HVA22 PF03134.19 CDJ95570.1 - 7.9e-05 22.5 1.5 0.0011 18.8 0.1 2.3 1 1 1 2 2 2 2 TB2/DP1, HVA22 family Pkinase PF00069.25 CDJ95571.1 - 5.3e-59 199.7 0.0 7.9e-59 199.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ95571.1 - 1.1e-24 87.1 0.0 2.8e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase DUF229 PF02995.17 CDJ95572.1 - 9.6e-34 116.8 0.2 5.8e-26 91.2 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF229) HIM1 PF08732.10 CDJ95573.1 - 0.016 14.7 0.1 0.045 13.3 0.0 1.7 1 1 1 2 2 2 0 HIM1 mRNA_cap_enzyme PF01331.19 CDJ95574.1 - 2.2e-64 216.9 0.1 3.6e-64 216.2 0.1 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 CDJ95574.1 - 1.2e-20 74.1 0.0 2.2e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DSPc PF00782.20 CDJ95574.1 - 1.9e-10 40.7 0.0 6.5e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DNA_ligase_A_M PF01068.21 CDJ95574.1 - 7e-07 29.1 0.0 0.00016 21.4 0.0 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Y_phosphatase PF00102.27 CDJ95574.1 - 0.011 15.3 0.2 0.042 13.4 0.0 1.8 2 0 0 2 2 2 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CDJ95574.1 - 0.068 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 CDJ95574.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Aldo_ket_red PF00248.21 CDJ95575.1 - 1.5e-10 40.7 0.0 1.8e-10 40.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Slx4 PF09494.10 CDJ95575.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Slx4 endonuclease hNIFK_binding PF12196.8 CDJ95576.1 - 0.019 14.5 0.1 0.019 14.5 0.1 2.0 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK DUF5543 PF17697.1 CDJ95576.1 - 0.35 11.2 2.2 0.68 10.2 2.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5543) SLAC1 PF03595.17 CDJ95577.1 - 0.0054 16.0 0.3 0.0068 15.7 0.3 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel NnrS PF05940.12 CDJ95577.1 - 0.0064 15.9 0.2 0.0077 15.6 0.2 1.0 1 0 0 1 1 1 1 NnrS protein Ac76 PF05814.11 CDJ95577.1 - 0.011 15.7 2.2 0.011 15.7 2.2 1.8 2 0 0 2 2 1 0 Orf76 (Ac76) SCAMP PF04144.13 CDJ95577.1 - 0.021 15.1 8.5 0.15 12.4 1.0 2.2 1 1 1 2 2 2 0 SCAMP family DUF4293 PF14126.6 CDJ95577.1 - 0.023 14.9 3.0 0.033 14.4 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) DUF2569 PF10754.9 CDJ95577.1 - 0.035 14.6 5.5 0.03 14.7 4.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) DUF2615 PF11027.8 CDJ95577.1 - 0.083 13.0 1.0 1.1 9.5 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) Sugar_tr PF00083.24 CDJ95577.1 - 0.087 11.7 4.2 0.12 11.2 4.2 1.3 1 0 0 1 1 1 0 Sugar (and other) transporter PMP22_Claudin PF00822.20 CDJ95577.1 - 0.1 12.5 3.9 0.096 12.6 3.0 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Phage_holin_3_6 PF07332.11 CDJ95577.1 - 0.11 12.5 7.9 45 4.1 0.0 2.7 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III PalH PF08733.10 CDJ95577.1 - 0.13 11.3 3.4 0.073 12.1 1.6 1.4 1 1 0 1 1 1 0 PalH/RIM21 Phtf-FEM1B_bdg PF12129.8 CDJ95577.1 - 0.14 12.0 1.4 0.3 10.9 1.0 1.7 1 1 1 2 2 2 0 Male germ-cell putative homeodomain transcription factor AA_permease_2 PF13520.6 CDJ95577.1 - 0.15 10.8 7.1 0.24 10.2 7.2 1.4 1 1 0 1 1 1 0 Amino acid permease LPG_synthase_TM PF03706.13 CDJ95577.1 - 0.52 9.8 5.8 0.53 9.8 2.2 2.0 1 1 2 3 3 3 0 Lysylphosphatidylglycerol synthase TM region EphA2_TM PF14575.6 CDJ95577.1 - 0.75 10.7 4.6 4.7 8.2 0.2 3.0 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain ABC_export PF16962.5 CDJ95577.1 - 1.8 6.9 9.6 0.92 7.9 8.1 1.4 1 1 0 1 1 1 0 Putative ABC exporter DUF1218 PF06749.12 CDJ95577.1 - 5.3 7.6 9.5 1.3 9.6 5.9 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) Wzy_C PF04932.15 CDJ95577.1 - 6.2 6.4 6.1 34 4.1 6.1 2.0 1 1 0 1 1 1 0 O-Antigen ligase DUF2207 PF09972.9 CDJ95577.1 - 8 5.1 6.5 5 5.8 4.9 1.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) IncD PF17628.2 CDJ95577.1 - 9.7 6.0 9.1 0.19 11.5 2.1 1.7 3 0 0 3 3 2 0 Inclusion membrane protein D NrsF PF06532.11 CDJ95580.1 - 0.16 11.7 5.5 0.2 11.3 5.5 1.1 1 0 0 1 1 1 0 Negative regulator of sigma F DUF2157 PF09925.9 CDJ95580.1 - 0.36 10.6 3.0 0.47 10.2 3.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) PDR_assoc PF08370.11 CDJ95580.1 - 0.59 9.9 2.5 0.36 10.6 0.3 1.8 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Choline_kinase PF01633.20 CDJ95581.1 - 2.4e-61 207.0 0.0 3.4e-61 206.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CDJ95581.1 - 1.4e-06 28.4 0.0 3.3e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family zf-C4 PF00105.18 CDJ95582.1 - 4.2e-26 91.2 15.7 8.3e-26 90.2 15.7 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ95582.1 - 4.5e-22 78.6 0.3 9.1e-22 77.7 0.3 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-RRPl_C4 PF17026.5 CDJ95582.1 - 0.62 10.2 9.2 0.24 11.5 5.6 2.1 3 0 0 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type EGF PF00008.27 CDJ95584.1 - 3.8e-27 94.2 209.3 2.7e-06 27.5 5.8 16.2 14 2 1 15 15 15 11 EGF-like domain Ephrin_rec_like PF07699.13 CDJ95584.1 - 6.8e-22 77.0 66.2 3.7e-13 49.0 6.4 7.6 6 1 1 7 7 7 5 Putative ephrin-receptor like HYR PF02494.16 CDJ95584.1 - 6.9e-13 48.7 0.3 2.2e-12 47.1 0.3 2.0 1 0 0 1 1 1 1 HYR domain EGF_2 PF07974.13 CDJ95584.1 - 4.1e-11 43.1 220.7 0.0047 17.3 10.8 15.1 12 1 2 14 14 14 10 EGF-like domain hEGF PF12661.7 CDJ95584.1 - 3.7e-09 36.9 182.0 7.6e-05 23.2 8.3 16.8 16 0 0 16 16 16 10 Human growth factor-like EGF PLA2G12 PF06951.11 CDJ95585.1 - 0.0051 16.7 5.4 0.0075 16.2 5.4 1.4 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) MADF_DNA_bdg PF10545.9 CDJ95586.1 - 1.2e-15 57.6 0.2 2.6e-15 56.5 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 CDJ95586.1 - 1.5e-06 28.2 0.5 3.3e-06 27.1 0.5 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CDJ95586.1 - 4e-05 23.9 0.3 7.3e-05 23.1 0.3 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain BMFP PF04380.13 CDJ95586.1 - 0.029 14.9 0.3 0.11 13.0 0.0 2.1 2 0 0 2 2 2 0 Membrane fusogenic activity Bclx_interact PF08945.10 CDJ95586.1 - 0.046 13.5 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain Ldl_recept_a PF00057.18 CDJ95588.1 - 9.5e-82 268.9 191.7 3.5e-13 49.5 7.7 13.0 13 0 0 13 13 13 10 Low-density lipoprotein receptor domain class A SGL PF08450.12 CDJ95588.1 - 1.9e-05 24.4 0.0 0.00033 20.3 0.0 2.6 3 0 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region FXa_inhibition PF14670.6 CDJ95588.1 - 0.014 15.7 13.1 0.014 15.7 13.1 7.7 8 0 0 8 8 8 0 Coagulation Factor Xa inhibitory site Mor PF08765.11 CDJ95589.1 - 0.17 11.9 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 Mor transcription activator family 7TM_GPCR_Srd PF10317.9 CDJ95590.1 - 4.5e-09 35.9 5.6 5.1e-09 35.7 5.6 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Str PF10326.9 CDJ95590.1 - 0.0043 16.5 3.6 0.0074 15.7 3.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str UPF0258 PF06789.12 CDJ95590.1 - 0.15 12.2 0.2 0.32 11.1 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) Phtf-FEM1B_bdg PF12129.8 CDJ95590.1 - 0.99 9.2 4.7 1.4 8.7 4.7 1.3 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor CRAL_TRIO PF00650.20 CDJ95591.1 - 1.4e-25 89.9 0.1 2e-25 89.3 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain DUF508 PF04370.12 CDJ95592.1 - 2.8e-14 53.1 0.4 3.6e-14 52.8 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF508) Hydrolase_like PF13242.6 CDJ95594.1 - 5.7e-16 58.3 0.1 2e-15 56.6 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 CDJ95594.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDJ95594.1 - 0.0024 18.2 0.2 0.0075 16.6 0.2 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CDJ95594.1 - 0.055 13.6 0.1 0.18 11.9 0.1 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Pkinase PF00069.25 CDJ95595.1 - 1.7e-33 116.1 0.0 2.2e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ95595.1 - 2.9e-14 53.0 0.0 5.8e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ95595.1 - 0.073 12.4 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 CDJ95595.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ95595.1 - 0.15 10.8 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase 7TM_GPCR_Srab PF10292.9 CDJ95596.1 - 7.9e-53 179.5 13.9 1e-52 179.1 13.9 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Srb PF02175.16 CDJ95596.1 - 6e-08 32.8 5.6 9.9e-08 32.0 5.6 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srb 7tm_1 PF00001.21 CDJ95596.1 - 0.00043 19.7 9.2 0.0006 19.2 9.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Sra PF02117.16 CDJ95596.1 - 0.011 14.6 11.8 0.016 14.1 11.8 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sra COX2_TM PF02790.15 CDJ95596.1 - 0.031 14.4 2.0 0.081 13.1 1.4 2.1 1 1 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain DUF4710 PF15828.5 CDJ95601.1 - 0.017 15.2 2.2 0.038 14.1 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) DEAD PF00270.29 CDJ95602.1 - 6.9e-17 61.8 0.5 8.4e-17 61.5 0.5 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 CDJ95602.1 - 0.0039 16.9 0.1 0.0045 16.7 0.1 1.1 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CDJ95602.1 - 0.0083 16.1 0.0 0.01 15.8 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CDJ95602.1 - 0.017 15.5 0.1 0.021 15.2 0.1 1.2 1 0 0 1 1 1 0 AAA domain YlbD_coat PF14071.6 CDJ95604.1 - 0.058 13.7 1.0 0.26 11.6 0.0 2.2 2 0 0 2 2 2 0 Putative coat protein UPF0242 PF06785.11 CDJ95604.1 - 1.3 9.1 13.7 3.1 7.9 4.5 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus zf-CCHC PF00098.23 CDJ95604.1 - 2.7 8.2 12.7 0.11 12.6 2.0 3.4 3 1 0 3 3 3 0 Zinc knuckle DUF3391 PF11871.8 CDJ95604.1 - 6.1 7.4 8.8 6 7.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) ANF_receptor PF01094.28 CDJ95605.1 - 1.7e-35 122.8 0.5 2.2e-35 122.4 0.5 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Spore_YpjB PF09577.10 CDJ95605.1 - 0.033 14.0 0.6 0.12 12.1 0.3 1.9 2 0 0 2 2 2 0 Sporulation protein YpjB (SpoYpjB) Peripla_BP_6 PF13458.6 CDJ95605.1 - 0.19 11.4 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Sec62 PF03839.16 CDJ95606.1 - 7.4e-16 58.3 3.0 7.4e-16 58.3 3.0 1.8 1 1 1 2 2 2 2 Translocation protein Sec62 DUF4636 PF15468.6 CDJ95606.1 - 0.038 13.7 3.1 0.049 13.3 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) RNA_pol_Rpc4 PF05132.14 CDJ95606.1 - 0.1 13.1 4.9 0.13 12.7 4.9 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 CDC45 PF02724.14 CDJ95606.1 - 0.24 9.7 7.7 0.26 9.6 7.7 1.0 1 0 0 1 1 1 0 CDC45-like protein PRKCSH PF07915.13 CDJ95606.1 - 0.45 11.5 6.3 0.94 10.5 6.3 1.7 1 1 0 1 1 1 0 Glucosidase II beta subunit-like protein DUF913 PF06025.12 CDJ95606.1 - 0.63 9.0 2.1 0.63 9.0 2.1 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 CDJ95606.1 - 0.92 9.3 6.2 1 9.1 6.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ95606.1 - 1.2 7.8 5.8 1.4 7.6 5.8 1.0 1 0 0 1 1 1 0 Presenilin FAM176 PF14851.6 CDJ95606.1 - 1.4 8.6 5.9 1.6 8.4 5.9 1.2 1 0 0 1 1 1 0 FAM176 family PALP PF00291.25 CDJ95607.1 - 2.1e-67 227.6 0.2 2.6e-67 227.3 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 CDJ95607.1 - 0.15 12.1 0.2 1.3 9.0 0.1 2.4 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Ribosomal_L37e PF01907.19 CDJ95608.1 - 8.3e-26 89.9 11.5 1.8e-25 88.8 11.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 CDJ95608.1 - 0.25 11.4 4.2 0.18 11.9 1.7 2.0 2 0 0 2 2 2 0 Double zinc ribbon DUF3349 PF11829.8 CDJ95609.1 - 0.014 16.2 27.0 6.1 7.7 0.8 8.7 6 0 0 6 6 6 0 Protein of unknown function (DUF3349) FUR PF01475.19 CDJ95609.1 - 0.39 10.9 6.7 1.6 8.9 0.8 3.8 3 0 0 3 3 3 0 Ferric uptake regulator family Carbpep_Y_N PF05388.11 CDJ95609.1 - 0.52 10.9 3.6 3.8 8.1 0.1 4.2 3 0 0 3 3 3 0 Carboxypeptidase Y pro-peptide FUSC PF04632.12 CDJ95609.1 - 6.1 5.2 17.7 0.25 9.8 0.3 3.5 3 0 0 3 3 3 0 Fusaric acid resistance protein family DUF2076 PF09849.9 CDJ95610.1 - 0.042 13.9 2.9 0.074 13.1 2.9 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) YqzE PF14038.6 CDJ95610.1 - 0.24 11.4 2.5 0.73 9.9 2.5 1.8 1 0 0 1 1 1 0 YqzE-like protein Profilin PF00235.19 CDJ95611.1 - 2.4e-33 115.1 0.1 2.9e-33 114.8 0.1 1.0 1 0 0 1 1 1 1 Profilin Tetraspanin PF00335.20 CDJ95612.1 - 4.6e-22 78.9 10.8 5.4e-22 78.6 10.8 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2981 PF11200.8 CDJ95612.1 - 0.023 14.5 2.8 0.032 14.0 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF4345 PF14248.6 CDJ95612.1 - 0.023 14.6 6.6 0.031 14.2 6.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4345) Ank_2 PF12796.7 CDJ95613.1 - 1.5e-13 51.1 12.6 4.5e-08 33.6 2.9 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ95613.1 - 1.1e-09 38.3 10.6 5.3e-07 29.8 2.6 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ95613.1 - 1.9e-06 27.8 4.8 0.012 16.1 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 CDJ95613.1 - 9.5e-05 22.9 5.1 0.0086 16.6 1.2 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CDJ95613.1 - 0.00049 20.4 7.3 0.31 11.6 0.3 3.3 3 0 0 3 3 3 2 Ankyrin repeat GILT PF03227.16 CDJ95615.1 - 5.1e-24 84.6 1.3 7.8e-24 84.0 1.3 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) GILT PF03227.16 CDJ95617.1 - 1.1e-23 83.5 1.6 1.9e-23 82.8 1.6 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) GILT PF03227.16 CDJ95618.1 - 1.8e-22 79.6 0.5 3.3e-22 78.8 0.5 1.5 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) fn3 PF00041.21 CDJ95619.1 - 1.3e-14 54.3 1.3 0.00029 21.1 0.0 3.4 3 0 0 3 3 3 3 Fibronectin type III domain DNA_pol_E_B PF04042.16 CDJ95620.1 - 0.075 12.4 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B DUF802 PF05650.11 CDJ95620.1 - 0.1 13.1 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF802) MH2 PF03166.14 CDJ95622.1 - 1.9e-48 165.2 0.0 2.7e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 CDJ95622.1 - 6.5e-34 116.2 0.2 1.1e-33 115.5 0.2 1.4 1 0 0 1 1 1 1 MH1 domain DUF1955 PF09205.10 CDJ95622.1 - 3.4e-05 23.6 0.0 5.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1955) Metallophos PF00149.28 CDJ95623.1 - 9.4e-41 140.6 0.1 1.2e-40 140.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDJ95623.1 - 1.9e-23 82.6 1.6 3.6e-23 81.7 1.0 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain BCAS3 PF12490.8 CDJ95624.1 - 0.0038 16.8 0.0 0.0069 15.9 0.0 1.5 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 3 WD40 PF00400.32 CDJ95624.1 - 0.05 14.5 0.7 2.6 9.0 0.0 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat TcdA_TcdB PF12919.7 CDJ95624.1 - 0.31 10.3 0.0 0.45 9.7 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain PB1 PF00564.24 CDJ95625.1 - 1.9e-12 46.9 0.1 3e-12 46.3 0.1 1.2 1 0 0 1 1 1 1 PB1 domain C1_1 PF00130.22 CDJ95627.1 - 0.0046 16.8 12.7 0.0094 15.8 12.7 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) HBS1_N PF08938.10 CDJ95628.1 - 0.076 13.3 0.0 1e+02 3.3 0.0 3.7 3 1 0 3 3 3 0 HBS1 N-terminus Antimicrobial_2 PF08023.12 CDJ95628.1 - 0.14 12.8 5.2 7 7.3 0.0 3.8 4 0 0 4 4 4 0 Frog antimicrobial peptide DUF3708 PF12501.8 CDJ95628.1 - 0.18 11.6 3.7 2 8.2 0.3 2.8 3 0 0 3 3 3 0 Phosphate ATP-binding cassette transporter TPX2 PF06886.11 CDJ95629.1 - 0.26 11.5 3.9 9 6.6 0.9 2.4 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) DUF4484 PF14831.6 CDJ95631.1 - 0.25 11.3 2.1 0.38 10.8 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) BACK PF07707.15 CDJ95631.1 - 1.5 8.9 4.8 1 9.5 2.2 2.0 2 0 0 2 2 2 0 BTB And C-terminal Kelch Slu7 PF11708.8 CDJ95632.1 - 3.1e-42 145.2 0.8 3.1e-42 145.2 0.8 3.3 2 1 1 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor SR-25 PF10500.9 CDJ95632.1 - 0.42 10.2 59.8 0.13 11.8 37.7 2.6 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ95632.1 - 0.96 9.8 12.4 2.5 8.5 5.6 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain Spem1 PF15670.5 CDJ95632.1 - 1.8 8.1 15.6 4.1 6.9 15.6 1.6 1 0 0 1 1 1 0 Spermatid maturation protein 1 DUF4603 PF15376.6 CDJ95632.1 - 2 5.7 29.3 2.8 5.2 29.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) GREB1 PF15782.5 CDJ95632.1 - 3.8 4.5 15.3 4.2 4.4 15.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ubiquitin PF00240.23 CDJ95634.1 - 1.4e-18 66.4 0.0 2.8e-18 65.4 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CDJ95634.1 - 8.3e-09 35.2 0.0 1.2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-C3HC4 PF00097.25 CDJ95634.1 - 3.3e-06 26.9 17.4 5.6e-06 26.1 17.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ95634.1 - 8.7e-06 25.7 15.1 1.6e-05 24.8 15.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDJ95634.1 - 2.2e-05 24.2 14.6 3.5e-05 23.6 14.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ95634.1 - 2.8e-05 24.3 16.1 4.5e-05 23.7 16.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CDJ95634.1 - 5e-05 23.2 15.0 8.4e-05 22.5 15.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDJ95634.1 - 0.0036 17.1 11.7 0.0081 16.0 11.7 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CDJ95634.1 - 0.015 15.1 18.7 0.051 13.4 18.7 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ95634.1 - 0.03 14.5 16.9 0.062 13.5 16.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ubiquitin_2 PF14560.6 CDJ95634.1 - 0.082 13.4 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain zf-rbx1 PF12678.7 CDJ95634.1 - 2.4 8.5 11.8 4.6 7.6 11.8 1.5 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 CDJ95634.1 - 2.5 7.9 11.5 6.8 6.6 11.4 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Lectin_C PF00059.21 CDJ95635.1 - 7.3e-10 39.5 0.0 1.2e-09 38.9 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain PI3_PI4_kinase PF00454.27 CDJ95638.1 - 9.5e-57 192.7 0.0 1.6e-55 188.6 0.0 2.3 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase SMG1 PF15785.5 CDJ95638.1 - 4.2e-39 134.5 7.7 8.1e-38 130.2 7.8 2.3 1 1 0 1 1 1 1 Serine/threonine-protein kinase smg-1 FATC PF02260.20 CDJ95638.1 - 1.4e-09 37.6 0.2 4.2e-09 36.1 0.2 1.9 1 0 0 1 1 1 1 FATC domain Nbl1_Borealin_N PF10444.9 CDJ95638.1 - 0.057 13.1 0.3 0.19 11.4 0.3 1.9 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal HEAT PF02985.22 CDJ95638.1 - 0.084 13.2 0.0 0.56 10.6 0.0 2.6 1 0 0 1 1 1 0 HEAT repeat FRB_dom PF08771.11 CDJ95638.1 - 0.093 13.2 3.1 0.1 13.0 0.0 2.7 2 1 1 3 3 3 0 FKBP12-rapamycin binding domain S4 PF01479.25 CDJ95639.1 - 4.4e-12 45.5 0.4 1.3e-11 44.0 0.1 2.0 2 0 0 2 2 2 1 S4 domain DUF4588 PF15251.6 CDJ95639.1 - 4.8e-10 39.6 0.4 8.2e-10 38.9 0.4 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Ribosomal_S4 PF00163.19 CDJ95639.1 - 0.00012 22.9 2.1 0.00024 21.9 2.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Topoisom_bac PF01131.20 CDJ95639.1 - 0.053 12.5 0.6 0.079 11.9 0.6 1.2 1 0 0 1 1 1 0 DNA topoisomerase PHTB1_N PF14727.6 CDJ95640.1 - 5.3e-62 210.5 0.1 7.7e-62 210.0 0.1 1.2 1 0 0 1 1 1 1 PTHB1 N-terminus PHTB1_C PF14728.6 CDJ95640.1 - 3.3e-38 131.8 0.0 4.9e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 PTHB1 C-terminus MIP PF00230.20 CDJ95642.1 - 7.9e-06 25.7 3.0 9.1e-06 25.5 3.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein NAD_binding_10 PF13460.6 CDJ95642.1 - 0.022 14.7 0.1 0.022 14.7 0.1 1.0 1 0 0 1 1 1 0 NAD(P)H-binding Ycf66_N PF07444.11 CDJ95643.1 - 0.66 10.1 6.8 2.5 8.3 2.0 2.4 2 1 0 2 2 2 0 Ycf66 protein N-terminus MARVEL PF01284.23 CDJ95643.1 - 7.8 6.5 14.5 30 4.6 14.6 1.7 1 1 0 1 1 1 0 Membrane-associating domain UDPGT PF00201.18 CDJ95644.1 - 2.5e-31 109.1 0.0 2.7e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ95644.1 - 3.8e-07 30.2 0.0 7.1e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Pkinase_Tyr PF07714.17 CDJ95645.1 - 1.7e-69 234.0 0.0 2.6e-69 233.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ95645.1 - 1.1e-42 146.2 0.0 1.7e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDJ95645.1 - 0.00064 19.8 0.1 0.041 14.0 0.0 2.6 2 0 0 2 2 2 1 SH2 domain Kinase-like PF14531.6 CDJ95645.1 - 0.0054 16.1 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CDJ95645.1 - 0.014 14.2 0.1 0.11 11.2 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Glyco_transf_54 PF04666.13 CDJ95646.1 - 1.9e-126 420.9 3.7 3.9e-69 232.7 0.3 2.1 2 0 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Pkinase_Tyr PF07714.17 CDJ95647.1 - 0.0041 16.4 0.0 3.9 6.7 0.0 2.6 2 1 1 3 3 3 2 Protein tyrosine kinase SRF-TF PF00319.18 CDJ95648.1 - 1.6e-19 69.1 0.1 2.6e-19 68.4 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) TMEM214 PF10151.9 CDJ95648.1 - 0.16 10.4 1.1 0.25 9.7 1.1 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DNA_pol_phi PF04931.13 CDJ95648.1 - 2.2 6.3 8.5 2.9 5.9 8.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi HTH_48 PF17906.1 CDJ95649.1 - 4.1e-18 65.2 0.3 5.6e-18 64.8 0.3 1.2 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_24 PF13412.6 CDJ95649.1 - 0.081 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_32 PF13565.6 CDJ95649.1 - 0.2 12.3 0.0 1.3 9.7 0.0 2.0 1 1 1 2 2 2 0 Homeodomain-like domain DUF89 PF01937.19 CDJ95650.1 - 1.8e-95 319.9 0.0 2e-95 319.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Borrelia_orfA PF02414.15 CDJ95650.1 - 0.13 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Borrelia ORF-A SPC25 PF06703.11 CDJ95651.1 - 7e-43 146.2 1.2 7.9e-43 146.1 1.2 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Nsp1_C PF05064.13 CDJ95652.1 - 7.4e-09 35.4 1.6 7.4e-09 35.4 1.6 2.7 2 1 0 2 2 2 1 Nsp1-like C-terminal region V_ATPase_I PF01496.19 CDJ95652.1 - 0.014 13.3 2.5 0.019 12.9 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Interferon PF00143.19 CDJ95652.1 - 0.017 15.3 1.2 0.047 13.9 1.2 1.7 1 0 0 1 1 1 0 Interferon alpha/beta domain Ribosomal_L5 PF00281.19 CDJ95652.1 - 0.05 13.9 0.2 19 5.7 0.0 2.7 2 0 0 2 2 2 0 Ribosomal protein L5 DUF4252 PF14060.6 CDJ95652.1 - 0.071 13.0 3.9 0.17 11.8 3.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) MLD PF11647.8 CDJ95652.1 - 0.12 12.7 0.5 0.29 11.4 0.5 1.7 1 0 0 1 1 1 0 Membrane Localization Domain DUF4201 PF13870.6 CDJ95652.1 - 0.16 11.7 10.2 2.5 7.8 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DASH_Dam1 PF08653.10 CDJ95652.1 - 0.24 11.2 2.9 9.1 6.2 0.0 3.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 ATP-synt_E_2 PF08112.11 CDJ95652.1 - 0.28 11.5 2.7 2 8.8 0.3 2.7 2 1 0 2 2 2 0 ATP synthase epsilon subunit PhaP_Bmeg PF09602.10 CDJ95652.1 - 0.33 10.9 8.1 0.29 11.1 4.1 2.3 1 1 2 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF1664 PF07889.12 CDJ95652.1 - 0.37 10.8 11.2 1.7 8.7 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) ParB PF08775.10 CDJ95652.1 - 0.54 10.8 7.1 0.2 12.1 3.6 2.0 2 1 0 2 2 2 0 ParB family CENP-F_leu_zip PF10473.9 CDJ95652.1 - 0.65 10.0 13.2 2.8 8.0 6.8 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.12 CDJ95652.1 - 2.1 8.8 8.3 8.6 6.9 0.1 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Nuc_rec_co-act PF08815.10 CDJ95652.1 - 2.3 8.1 0.0 2.3 8.1 0.0 3.3 4 0 0 4 4 4 0 Nuclear receptor coactivator Abhydrolase_1 PF00561.20 CDJ95653.1 - 5.5e-14 52.4 0.2 6.4e-14 52.2 0.2 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ95653.1 - 0.00051 19.4 0.1 0.00074 18.9 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 aGPT-Pplase3 PF18746.1 CDJ95653.1 - 0.037 13.4 0.1 0.041 13.2 0.1 1.1 1 0 0 1 1 1 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 3 zf-H2C2_2 PF13465.6 CDJ95655.1 - 7.9e-15 54.5 25.1 1.3e-09 38.0 1.2 5.0 5 1 0 5 5 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 CDJ95655.1 - 6.4e-14 51.5 28.9 2.2e-05 24.6 3.7 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ95655.1 - 1.6e-10 40.9 28.0 0.0011 19.7 3.8 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CDJ95655.1 - 1.5e-05 25.7 12.4 0.16 12.7 0.2 3.4 2 2 1 3 3 3 3 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 CDJ95655.1 - 0.00043 19.8 9.3 1.3 8.7 1.4 4.3 4 0 0 4 4 4 1 Ubiquitin-Binding Zinc Finger zf-H2C2_5 PF13909.6 CDJ95655.1 - 0.00058 19.6 3.1 0.00058 19.6 3.1 4.2 5 0 0 5 5 4 2 C2H2-type zinc-finger domain PHD_Oberon PF07227.11 CDJ95655.1 - 0.0011 18.8 8.5 0.054 13.4 4.8 2.2 1 1 1 2 2 2 2 PHD - plant homeodomain finger protein zf-C2H2_11 PF16622.5 CDJ95655.1 - 0.0024 17.6 20.5 0.061 13.1 1.6 4.2 4 0 0 4 4 4 2 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 CDJ95655.1 - 0.0033 17.5 17.3 0.83 9.8 0.2 4.3 3 1 1 4 4 4 2 Zinc ribbon domain zf-met PF12874.7 CDJ95655.1 - 0.0051 17.1 16.1 0.074 13.5 2.1 4.0 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CDJ95655.1 - 0.06 13.4 26.8 0.43 10.7 3.1 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ95655.1 - 0.1 12.9 16.4 1.1 9.7 0.2 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 CDJ95655.1 - 0.11 12.8 11.1 0.69 10.2 2.1 3.1 1 1 2 3 3 3 0 C2H2-type zinc ribbon PhnA_Zn_Ribbon PF08274.12 CDJ95655.1 - 0.12 12.4 3.3 1.3 9.0 3.3 2.4 1 1 0 1 1 1 0 PhnA Zinc-Ribbon XPA_N PF01286.18 CDJ95655.1 - 0.13 12.3 10.7 12 6.0 0.0 4.3 4 0 0 4 4 4 0 XPA protein N-terminal zf_C2H2_ZHX PF18387.1 CDJ95655.1 - 0.26 10.9 0.1 0.26 10.9 0.1 3.7 4 1 1 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HC_2 PF13913.6 CDJ95655.1 - 0.37 10.7 0.2 0.37 10.7 0.2 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type FYVE PF01363.21 CDJ95655.1 - 0.91 9.7 18.3 6.9e+02 0.5 18.3 2.5 1 1 0 1 1 1 0 FYVE zinc finger zf-dskA_traR PF01258.17 CDJ95655.1 - 0.98 9.4 5.4 5.3 7.1 0.0 3.5 4 0 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger C1_2 PF03107.16 CDJ95655.1 - 1.2 9.5 16.9 1.1e+02 3.2 0.1 4.0 2 1 0 2 2 2 0 C1 domain zinc_ribbon_15 PF17032.5 CDJ95655.1 - 3.9 8.3 10.9 18 6.2 6.6 2.8 1 1 2 3 3 3 0 zinc-ribbon family FYVE_2 PF02318.16 CDJ95655.1 - 4.3 7.6 14.6 6.3 7.0 3.0 2.4 1 1 1 2 2 2 0 FYVE-type zinc finger zf-Sec23_Sec24 PF04810.15 CDJ95655.1 - 4.5 7.4 8.8 55 3.9 0.3 3.9 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger Zf_RING PF16744.5 CDJ95655.1 - 6.2 7.0 11.6 4.3 7.5 1.9 2.7 1 1 2 3 3 3 0 KIAA1045 RING finger LRR_8 PF13855.6 CDJ95656.1 - 5.2e-49 163.8 47.3 2.1e-14 53.0 1.8 4.9 3 1 2 5 5 5 5 Leucine rich repeat I-set PF07679.16 CDJ95656.1 - 1.5e-28 98.7 0.0 5.2e-16 58.5 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ95656.1 - 3.1e-26 91.8 0.0 3.4e-13 50.0 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain LRR_4 PF12799.7 CDJ95656.1 - 7.3e-21 73.9 34.2 1.8e-06 28.2 2.4 5.9 5 1 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CDJ95656.1 - 3.7e-16 59.3 0.0 1.8e-12 47.4 0.0 2.9 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) Ig_2 PF13895.6 CDJ95656.1 - 3.3e-15 56.2 0.0 3.4e-07 30.5 0.0 3.3 2 1 1 3 3 3 2 Immunoglobulin domain ig PF00047.25 CDJ95656.1 - 9.2e-14 51.4 0.0 1.4e-07 31.6 0.0 3.9 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 CDJ95656.1 - 3.9e-12 46.3 0.0 0.074 13.2 0.0 4.8 3 2 0 3 3 3 3 Immunoglobulin V-set domain LRR_9 PF14580.6 CDJ95656.1 - 9e-08 31.8 12.1 0.0012 18.4 3.6 3.2 1 1 3 4 4 4 4 Leucine-rich repeat Izumo-Ig PF16706.5 CDJ95656.1 - 2.1e-06 27.7 0.0 0.022 14.8 0.0 3.3 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain LRR_1 PF00560.33 CDJ95656.1 - 4.1e-06 26.6 33.1 2.9 8.8 0.3 10.1 11 0 0 11 11 10 3 Leucine Rich Repeat Ig_6 PF18452.1 CDJ95656.1 - 0.00023 20.7 0.0 1.4 8.6 0.0 3.6 3 0 0 3 3 3 1 Immunoglobulin domain V-set_CD47 PF08204.11 CDJ95656.1 - 0.056 13.4 0.0 32 4.5 0.0 3.5 2 1 1 3 3 3 0 CD47 immunoglobulin-like domain Ig_C17orf99 PF17736.1 CDJ95656.1 - 0.11 12.5 0.0 2.1 8.5 0.0 2.4 2 0 0 2 2 2 0 C17orf99 Ig domain Ig_4 PF16680.5 CDJ95656.1 - 0.14 12.4 0.0 3.1 8.1 0.0 2.6 3 0 0 3 3 2 0 T-cell surface glycoprotein CD3 delta chain LPD24 PF18839.1 CDJ95656.1 - 0.17 12.2 0.1 1.7 9.0 0.0 2.4 3 0 0 3 3 2 0 Large polyvalent protein associated domain 24 LRR_6 PF13516.6 CDJ95656.1 - 0.74 10.0 38.2 1.7 8.9 0.7 9.2 10 0 0 10 10 9 0 Leucine Rich repeat PH_15 PF17339.2 CDJ95657.1 - 2.3e-28 98.2 0.0 3.7e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 PH domain TTR-52 PF01060.23 CDJ95658.1 - 1.5e-27 96.1 0.1 3.6e-27 94.9 0.1 1.7 2 0 0 2 2 2 1 Transthyretin-like family BTB PF00651.31 CDJ95658.1 - 7.8e-08 32.5 0.0 4e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain RVT_1 PF00078.27 CDJ95660.1 - 7.4e-19 68.1 0.0 8.9e-19 67.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CDJ95661.1 - 2.5e-19 69.7 0.0 3e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ion_trans_2 PF07885.16 CDJ95662.1 - 3e-20 72.0 22.3 3.8e-11 42.8 2.0 3.2 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CDJ95662.1 - 0.0054 16.0 15.7 0.032 13.5 1.8 2.2 2 0 0 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.16 CDJ95663.1 - 5.9e-26 90.2 19.5 1.1e-14 54.2 0.9 3.4 3 1 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CDJ95663.1 - 2.7e-08 33.4 10.6 6.7e-05 22.2 0.4 2.4 2 0 0 2 2 2 2 Ion transport protein TssO PF17561.2 CDJ95663.1 - 0.21 11.7 0.0 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 Type VI secretion system, TssO DUF1676 PF07898.13 CDJ95663.1 - 0.27 11.3 3.1 0.85 9.6 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1676) IRK PF01007.20 CDJ95663.1 - 3.3 7.5 9.2 1.2 9.0 0.0 3.6 4 0 0 4 4 4 0 Inward rectifier potassium channel transmembrane domain Ephrin PF00812.17 CDJ95665.1 - 1.7e-17 63.7 0.1 8.8e-17 61.4 0.1 2.0 1 1 0 1 1 1 1 Ephrin D5_N PF08706.11 CDJ95665.1 - 0.11 12.7 0.1 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 D5 N terminal like Innexin PF00876.18 CDJ95666.1 - 6.1e-87 292.2 6.4 7.3e-87 291.9 6.4 1.0 1 0 0 1 1 1 1 Innexin MAM PF00629.23 CDJ95667.1 - 0.0013 18.7 5.8 0.42 10.5 0.0 3.1 4 0 0 4 4 4 2 MAM domain, meprin/A5/mu PrmA PF06325.13 CDJ95668.1 - 2.4e-12 46.9 0.0 3.8e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CDJ95668.1 - 1.1e-08 35.7 0.0 3.8e-08 33.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ95668.1 - 9.2e-07 28.8 0.0 2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 CDJ95668.1 - 3.5e-06 26.9 0.0 5.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 CDJ95668.1 - 7.3e-06 25.9 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ95668.1 - 2.9e-05 23.7 0.0 5.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 CDJ95668.1 - 4.4e-05 22.7 0.0 7.2e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 CDJ95668.1 - 8.7e-05 22.4 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 CDJ95668.1 - 0.00011 22.8 0.0 0.00044 20.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 CDJ95668.1 - 0.00055 19.9 0.0 0.0017 18.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CDJ95668.1 - 0.0012 18.5 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 CMAS PF02353.20 CDJ95668.1 - 0.016 14.6 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 CDJ95668.1 - 0.19 11.5 0.1 0.89 9.3 0.0 2.1 3 0 0 3 3 3 0 Lysine methyltransferase GLTSCR1 PF15249.6 CDJ95669.1 - 1.4e-18 67.2 2.3 6.5e-18 65.1 2.3 2.3 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein RVT_1 PF00078.27 CDJ95671.1 - 2.5e-19 69.7 0.0 3e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4166 PF13761.6 CDJ95672.1 - 0.14 11.9 0.1 0.17 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4166) Peptidase_A17 PF05380.13 CDJ95673.1 - 3.9e-34 118.0 0.2 8.6e-34 116.9 0.0 1.7 2 0 0 2 2 2 1 Pao retrotransposon peptidase RVT_1 PF00078.27 CDJ95673.1 - 4.7e-09 36.1 0.0 9.5e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Keratin_2_head PF16208.5 CDJ95675.1 - 0.0018 18.4 13.1 0.0018 18.4 13.1 2.3 2 0 0 2 2 2 1 Keratin type II head Hyphal_reg_CWP PF11765.8 CDJ95675.1 - 0.028 13.3 0.2 19 4.0 0.0 4.1 5 0 0 5 5 5 0 Hyphally regulated cell wall protein N-terminal CDCA PF18484.1 CDJ95675.1 - 4.9 7.0 45.3 0.95 9.3 1.0 6.6 2 2 4 6 6 6 0 Cadmium carbonic anhydrase repeat SSF PF00474.17 CDJ95676.1 - 1.2e-36 126.4 20.0 1.8e-36 125.9 20.0 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Ion_trans PF00520.31 CDJ95677.1 - 1.1e-97 326.1 97.7 8.3e-33 113.6 20.3 4.1 4 0 0 4 4 4 4 Ion transport protein Pkinase PF00069.25 CDJ95678.1 - 3.4e-26 92.2 0.0 2.3e-14 53.4 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ95678.1 - 1.6e-15 57.1 0.1 8.4e-08 31.8 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDJ95678.1 - 0.037 13.3 0.0 0.066 12.5 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Njmu-R1 PF15053.6 CDJ95678.1 - 0.083 12.0 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Mjmu-R1-like protein family FH2 PF02181.23 CDJ95681.1 - 2.7e-65 220.9 0.8 2.7e-65 220.9 0.8 1.5 2 0 0 2 2 2 1 Formin Homology 2 Domain RPN13_C PF16550.5 CDJ95681.1 - 0.11 12.7 0.7 1 9.5 0.1 2.8 2 1 0 2 2 2 0 UCH-binding domain Mcl1_mid PF12341.8 CDJ95684.1 - 3.5e-61 207.2 0.3 9.1e-61 205.8 0.2 1.7 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 CDJ95684.1 - 0.0035 17.6 0.0 0.66 10.3 0.0 3.3 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain HMG_box_2 PF09011.10 CDJ95684.1 - 0.013 16.1 2.1 0.035 14.7 2.1 1.8 1 0 0 1 1 1 0 HMG-box domain WD40 PF00400.32 CDJ95684.1 - 0.017 16.0 13.1 0.64 11.0 0.4 6.1 5 1 1 6 6 6 0 WD domain, G-beta repeat HMG_box PF00505.19 CDJ95684.1 - 0.36 11.3 3.1 0.24 11.8 0.7 2.0 2 0 0 2 2 2 0 HMG (high mobility group) box EF1G PF00647.19 CDJ95685.1 - 5.1e-50 168.0 0.6 1.1e-49 166.9 0.6 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 CDJ95685.1 - 3.5e-11 43.2 0.0 1.2e-10 41.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDJ95685.1 - 1.4e-06 28.4 0.1 5.3e-06 26.6 0.1 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDJ95685.1 - 1.3e-05 25.1 0.1 2.8e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3981 PF13139.6 CDJ95686.1 - 0.069 13.5 0.0 0.095 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3981) PIF1 PF05970.14 CDJ95688.1 - 3.7e-102 342.2 0.0 4.9e-102 341.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 CDJ95688.1 - 9.1e-62 208.6 0.0 1.6e-61 207.9 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 CDJ95688.1 - 7.9e-11 42.0 0.0 1.5e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ95688.1 - 3.8e-05 24.1 0.0 0.00011 22.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 CDJ95688.1 - 0.00028 19.0 0.1 0.00058 17.9 0.0 1.4 2 0 0 2 2 2 1 Helicase Viral_helicase1 PF01443.18 CDJ95688.1 - 0.00075 19.3 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 CDJ95688.1 - 0.0036 17.3 0.0 0.0093 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CDJ95688.1 - 0.013 15.5 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 CDJ95688.1 - 0.021 14.6 0.2 0.051 13.4 0.2 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Phage_GPA PF05840.13 CDJ95688.1 - 0.059 12.5 0.0 0.17 10.9 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage replication gene A protein (GPA) AAA_22 PF13401.6 CDJ95688.1 - 0.083 13.2 0.0 1 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CDJ95688.1 - 0.12 12.7 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 CDJ95688.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Focadhesin PF11229.8 CDJ95689.1 - 0.0068 14.7 0.0 0.014 13.6 0.0 1.4 1 0 0 1 1 1 1 Focadhesin HEAT_2 PF13646.6 CDJ95689.1 - 0.13 12.7 1.0 1.6 9.2 0.5 2.7 2 0 0 2 2 2 0 HEAT repeats Neur_chan_LBD PF02931.23 CDJ95690.1 - 1.1e-75 253.8 1.6 1.6e-75 253.3 1.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ95690.1 - 1e-51 176.4 3.4 1.3e-51 176.0 3.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2678 PF10856.8 CDJ95690.1 - 0.002 18.0 2.2 0.0048 16.8 2.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) Abhydrolase_3 PF07859.13 CDJ95691.1 - 4.5e-58 196.6 0.0 7.7e-43 146.8 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CDJ95691.1 - 1.3e-08 34.6 0.0 0.0011 18.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 CDJ95691.1 - 3.6e-05 22.8 0.0 5.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme COesterase PF00135.28 CDJ95691.1 - 0.0004 19.4 0.0 0.0036 16.2 0.1 2.0 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_1 PF00561.20 CDJ95691.1 - 0.0012 18.5 0.1 0.0023 17.6 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ95691.1 - 0.0052 16.1 0.0 0.0098 15.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 CDJ95691.1 - 0.025 13.4 0.0 0.04 12.8 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 CDJ95692.1 - 1.7e-58 198.0 0.0 1e-42 146.4 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CDJ95692.1 - 5e-09 36.0 0.0 0.00062 19.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 CDJ95692.1 - 4.2e-05 22.6 0.0 6.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme COesterase PF00135.28 CDJ95692.1 - 0.00013 21.0 0.0 0.0075 15.2 0.0 2.1 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_1 PF00561.20 CDJ95692.1 - 0.00092 18.9 0.0 0.0014 18.3 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CDJ95692.1 - 0.012 14.5 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase DLH PF01738.18 CDJ95692.1 - 0.081 12.5 0.1 18 4.8 0.0 2.7 2 1 0 2 2 2 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 CDJ95692.1 - 0.2 10.9 0.0 0.56 9.4 0.0 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DUF5385 PF17359.2 CDJ95693.1 - 0.11 12.0 1.4 0.18 11.4 0.0 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5385) PIG-P PF08510.12 CDJ95693.1 - 0.12 12.2 0.3 0.31 11.0 0.2 1.8 1 1 0 1 1 1 0 PIG-P Neur_chan_memb PF02932.16 CDJ95693.1 - 0.31 11.1 6.4 0.18 11.8 4.2 1.5 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SOBP PF15279.6 CDJ95693.1 - 3 8.4 17.6 4.1 7.9 17.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein PWI PF01480.17 CDJ95694.1 - 1.8e-28 98.6 0.5 3.6e-28 97.7 0.5 1.5 1 0 0 1 1 1 1 PWI domain PIG-L PF02585.17 CDJ95696.1 - 6.4e-27 94.8 0.0 8.4e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase TMEM189_B_dmain PF10520.9 CDJ95697.1 - 0.039 14.1 0.4 0.058 13.5 0.0 1.5 2 1 0 2 2 2 0 B domain of TMEM189, localisation domain DUF281 PF03436.13 CDJ95698.1 - 0.12 12.8 8.5 0.34 11.3 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF281) TRAM_LAG1_CLN8 PF03798.16 CDJ95699.1 - 2.6e-34 118.7 15.9 3.5e-34 118.3 15.9 1.2 1 0 0 1 1 1 1 TLC domain FERM_F1 PF18379.1 CDJ95699.1 - 0.038 14.0 0.3 0.11 12.5 0.3 1.7 1 0 0 1 1 1 0 FERM F1 ubiquitin-like domain LIM PF00412.22 CDJ95700.1 - 1.9e-27 95.2 22.7 1.3e-13 51.0 6.4 2.5 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 CDJ95700.1 - 2.4e-18 65.7 0.2 4.4e-18 64.9 0.2 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ95700.1 - 0.0028 17.5 0.3 0.01 15.7 0.0 2.1 2 0 0 2 2 2 1 Homeobox KN domain Peptidase_C1 PF00112.23 CDJ95701.1 - 1.3e-57 195.4 5.6 1.6e-57 195.1 5.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Innexin PF00876.18 CDJ95702.1 - 1e-56 192.8 3.9 1.1e-56 192.6 3.9 1.0 1 0 0 1 1 1 1 Innexin CD52 PF15116.6 CDJ95702.1 - 0.11 12.5 1.3 0.19 11.7 1.3 1.4 1 0 0 1 1 1 0 CAMPATH-1 antigen Neur_chan_LBD PF02931.23 CDJ95703.1 - 6.8e-76 254.5 2.6 9e-76 254.1 2.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ95703.1 - 7.8e-56 189.8 4.8 3.1e-55 187.8 4.8 1.8 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Claudin_2 PF13903.6 CDJ95703.1 - 0.61 9.8 4.2 1.2 8.9 4.2 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DZF PF07528.14 CDJ95704.1 - 1e-52 179.3 0.0 1.5e-52 178.7 0.0 1.3 1 0 0 1 1 1 1 DZF domain zf-met PF12874.7 CDJ95704.1 - 1.3e-21 76.2 16.2 2.2e-07 31.0 0.4 3.9 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDJ95704.1 - 5.4e-15 55.2 14.9 7.9e-05 22.8 1.8 3.5 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding HRXXH PF13933.6 CDJ95704.1 - 0.012 15.1 0.6 0.012 15.1 0.6 2.1 2 1 1 3 3 3 0 Putative peptidase family zf-C2H2_2 PF12756.7 CDJ95704.1 - 0.016 15.5 14.7 3.3 8.1 0.7 4.0 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) DUF3449 PF11931.8 CDJ95704.1 - 0.032 14.0 7.7 0.95 9.2 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) zf-U1 PF06220.12 CDJ95704.1 - 0.28 11.0 15.8 0.75 9.6 1.6 3.5 3 0 0 3 3 3 0 U1 zinc finger zf-C2H2_4 PF13894.6 CDJ95704.1 - 0.82 10.7 14.1 6.3 7.9 0.1 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CDJ95704.1 - 3 8.5 15.9 2.4 8.8 0.8 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type FmiP_Thoc5 PF09766.9 CDJ95705.1 - 6.6e-85 285.6 0.4 8.5e-85 285.2 0.4 1.0 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 Collagen PF01391.18 CDJ95706.1 - 8.2e-19 67.1 102.2 1.2e-06 28.1 34.3 4.2 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ95706.1 - 8.1e-13 48.2 0.1 1.3e-12 47.6 0.1 1.3 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ95707.1 - 1.5e-21 75.9 89.1 5.9e-11 42.0 28.7 3.4 3 0 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ95707.1 - 6.2e-13 48.6 0.1 8.1e-13 48.2 0.1 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain DAO PF01266.24 CDJ95708.1 - 2.1e-32 113.1 0.0 2.5e-32 112.9 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase RNA_POL_M_15KD PF02150.16 CDJ95709.1 - 0.0036 17.1 0.7 0.0083 16.0 0.7 1.6 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 CDJ95709.1 - 0.037 14.0 0.2 0.08 12.9 0.2 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.6 CDJ95709.1 - 0.59 9.9 3.2 1.8 8.4 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Prefoldin PF02996.17 CDJ95710.1 - 2.9e-15 56.2 0.3 2.9e-15 56.2 0.3 2.6 2 0 0 2 2 2 1 Prefoldin subunit Ferlin_C PF16165.5 CDJ95710.1 - 9 6.2 11.1 0.82 9.6 1.0 2.7 2 0 0 2 2 2 0 Ferlin C-terminus UcrQ PF02939.16 CDJ95714.1 - 1.3e-25 89.2 2.5 1.4e-25 89.0 2.5 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 CDJ95714.1 - 0.045 14.2 0.3 0.28 11.6 0.3 1.9 1 1 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 CI-B14_5a PF07347.12 CDJ95715.1 - 1e-13 50.9 0.0 1.5e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Pkinase_Tyr PF07714.17 CDJ95716.1 - 1.9e-81 273.1 0.0 2.4e-81 272.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ95716.1 - 5.7e-52 176.7 0.0 7.9e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CDJ95716.1 - 0.0061 15.9 0.0 0.044 13.1 0.1 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family SH2 PF00017.24 CDJ95716.1 - 0.014 15.4 0.0 0.055 13.6 0.0 2.0 1 1 0 1 1 1 0 SH2 domain HP0268 PF18618.1 CDJ95716.1 - 0.056 13.9 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 HP0268 DUF3664 PF12406.8 CDJ95717.1 - 0.17 12.6 7.4 0.27 11.9 7.4 1.3 1 0 0 1 1 1 0 Surface protein Pkinase_Tyr PF07714.17 CDJ95718.1 - 4.8e-56 189.9 0.0 5.8e-56 189.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ95718.1 - 3.6e-37 128.2 0.0 4.4e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ95718.1 - 0.0053 16.1 0.0 0.0071 15.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDJ95718.1 - 0.049 13.0 0.0 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDJ95718.1 - 0.099 11.4 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase PNPase PF03726.14 CDJ95718.1 - 0.16 12.5 0.0 0.3 11.6 0.0 1.4 1 0 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Pkinase_Tyr PF07714.17 CDJ95719.1 - 3e-81 272.5 0.0 3.9e-81 272.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ95719.1 - 1.3e-50 172.2 0.0 2.4e-50 171.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CDJ95719.1 - 0.00056 19.3 0.0 0.0015 17.9 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_15 PF09445.10 CDJ95720.1 - 8.5e-44 149.0 0.0 1.4e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Forkhead PF00250.18 CDJ95720.1 - 2.2e-32 111.1 0.0 5.2e-32 109.9 0.0 1.7 1 0 0 1 1 1 1 Forkhead domain Met_10 PF02475.16 CDJ95720.1 - 4.3e-08 33.1 0.0 8.8e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 CDJ95720.1 - 2.1e-06 28.4 0.1 1.5e-05 25.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 CDJ95720.1 - 5.8e-06 26.1 0.0 1.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 CDJ95720.1 - 1.6e-05 24.8 0.0 3.8e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CDJ95720.1 - 0.00012 21.7 0.0 0.0003 20.5 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 CDJ95720.1 - 0.0012 19.5 0.0 0.0043 17.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CDJ95720.1 - 0.0059 16.0 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) N6_N4_Mtase PF01555.18 CDJ95720.1 - 0.064 13.0 0.7 0.5 10.0 0.0 2.4 2 0 0 2 2 2 0 DNA methylase Methyltransf_18 PF12847.7 CDJ95720.1 - 0.12 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 CDJ95720.1 - 0.13 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F ADH_zinc_N PF00107.26 CDJ95720.1 - 0.15 12.0 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PLAT PF01477.23 CDJ95721.1 - 3.3e-25 88.9 2.7 2.6e-11 44.1 0.1 5.0 5 0 0 5 5 5 4 PLAT/LH2 domain DCX PF03607.17 CDJ95721.1 - 1.4e-22 79.5 0.1 3.3e-16 59.1 0.0 3.2 3 0 0 3 3 3 2 Doublecortin IQ PF00612.27 CDJ95721.1 - 4.1e-06 26.1 1.0 8.7e-06 25.1 1.0 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Orbi_VP2 PF00898.17 CDJ95721.1 - 0.19 9.5 1.4 0.27 9.0 1.4 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP2 TrmE_N PF10396.9 CDJ95722.1 - 1.1e-32 112.7 0.0 2.7e-32 111.5 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 CDJ95722.1 - 2.8e-24 85.4 0.1 6.2e-24 84.3 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MnmE_helical PF12631.7 CDJ95722.1 - 1.3e-20 74.4 1.4 1.9e-20 73.9 1.4 1.2 1 0 0 1 1 1 1 MnmE helical domain FeoB_N PF02421.18 CDJ95722.1 - 2.3e-13 50.0 0.0 3.4e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B SH2 PF00017.24 CDJ95722.1 - 7.1e-11 42.0 0.1 1.5e-10 41.1 0.1 1.6 1 0 0 1 1 1 1 SH2 domain Dynamin_N PF00350.23 CDJ95722.1 - 2.4e-06 27.7 0.1 0.00038 20.5 0.0 2.4 1 1 1 2 2 2 1 Dynamin family Arf PF00025.21 CDJ95722.1 - 4.4e-06 26.2 0.0 1.7e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CDJ95722.1 - 2.7e-05 24.1 0.0 0.16 11.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Ras PF00071.22 CDJ95722.1 - 5.1e-05 22.9 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 CDJ95722.1 - 0.00042 19.9 0.1 0.046 13.2 0.1 2.5 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 CDJ95722.1 - 0.0008 19.6 0.0 0.0041 17.3 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 CDJ95722.1 - 0.0021 18.3 0.0 0.0089 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 CDJ95722.1 - 0.015 14.8 0.1 0.028 13.8 0.1 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AIG1 PF04548.16 CDJ95722.1 - 0.045 13.1 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family AAA_16 PF13191.6 CDJ95722.1 - 0.11 12.8 1.4 1.7 9.0 1.0 2.7 1 1 1 2 2 2 0 AAA ATPase domain Med23 PF11573.8 CDJ95723.1 - 1.4e-229 765.1 15.7 1.8e-229 764.8 15.7 1.0 1 0 0 1 1 1 1 Mediator complex subunit 23 Thymidylat_synt PF00303.19 CDJ95724.1 - 2e-110 368.2 0.0 3.3e-110 367.4 0.0 1.4 1 0 0 1 1 1 1 Thymidylate synthase zf-H2C2_2 PF13465.6 CDJ95724.1 - 4.6e-41 137.5 71.3 1.4e-07 31.6 0.3 13.1 15 0 0 15 15 15 8 Zinc-finger double domain zf-C2H2 PF00096.26 CDJ95724.1 - 1.5e-28 97.6 91.4 0.013 15.9 0.2 15.9 16 0 0 16 16 16 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ95724.1 - 3.9e-20 70.8 94.1 0.004 17.9 1.6 16.5 17 0 0 17 17 17 9 C2H2-type zinc finger TPP1 PF10341.9 CDJ95724.1 - 0.08 12.9 0.0 0.27 11.2 0.0 1.9 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD WD40 PF00400.32 CDJ95724.1 - 0.69 10.9 3.6 1 10.4 0.8 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat Ribosomal_S27e PF01667.17 CDJ95724.1 - 0.74 9.6 11.9 0.34 10.6 0.1 4.4 4 1 1 5 5 5 0 Ribosomal protein S27 FOXP-CC PF16159.5 CDJ95724.1 - 1.3 9.7 6.2 2.3 8.9 0.1 3.7 4 0 0 4 4 4 0 FOXP coiled-coil domain zf-CHCC PF10276.9 CDJ95724.1 - 5.6 7.1 11.9 22 5.2 0.2 5.2 4 0 0 4 4 4 0 Zinc-finger domain GAGA PF09237.11 CDJ95724.1 - 8.8 6.2 13.3 4.7 7.1 0.3 4.5 4 0 0 4 4 4 0 GAGA factor Gon7 PF08738.10 CDJ95725.1 - 0.59 10.2 11.0 2.7 8.1 11.0 2.0 1 1 0 1 1 1 0 Gon7 family PBP1_TM PF14812.6 CDJ95725.1 - 1.3 9.4 10.4 0.036 14.4 3.5 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CAP PF00188.26 CDJ95726.1 - 1.9e-20 74.0 0.0 3.3e-10 40.9 0.0 2.6 2 1 0 2 2 2 2 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ95726.1 - 0.037 14.3 2.1 10 6.4 0.4 2.8 3 0 0 3 3 3 0 Ancylostoma-associated secreted protein related SOG2 PF10428.9 CDJ95726.1 - 1.5 7.9 23.1 2.2 7.4 23.1 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 CDJ95726.1 - 7.5 6.4 10.6 9.5 6.0 10.6 1.1 1 0 0 1 1 1 0 SPX domain CAP PF00188.26 CDJ95727.1 - 7.5e-12 46.2 0.1 1e-11 45.7 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ95727.1 - 0.065 13.5 0.3 0.34 11.2 0.3 2.2 1 1 0 1 1 1 0 Ancylostoma-associated secreted protein related Squash PF00299.18 CDJ95727.1 - 0.16 12.0 3.3 0.37 10.8 3.3 1.6 1 0 0 1 1 1 0 Squash family serine protease inhibitor RVT_1 PF00078.27 CDJ95728.1 - 0.052 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) SAP PF02037.27 CDJ95729.1 - 8.1e-10 38.2 0.2 1.5e-09 37.4 0.2 1.5 1 0 0 1 1 1 1 SAP domain Mto2_bdg PF12808.7 CDJ95729.1 - 0.086 13.1 0.2 0.17 12.2 0.2 1.5 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region RVT_1 PF00078.27 CDJ95732.1 - 5.4e-06 26.1 0.0 6.6e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDJ95733.1 - 3.7e-06 26.8 0.1 5.2e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF4158 PF13700.6 CDJ95734.1 - 0.036 13.9 0.1 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4158) DUF5610 PF18433.1 CDJ95734.1 - 0.86 10.1 7.0 0.25 11.8 0.3 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF5610) PGI PF00342.19 CDJ95735.1 - 2.8e-246 817.7 0.1 3.3e-246 817.5 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase UQ_con PF00179.26 CDJ95736.1 - 6.1e-52 175.0 0.0 6.9e-52 174.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PHTB1_C PF14728.6 CDJ95737.1 - 0.0011 18.1 2.2 0.0016 17.6 2.2 1.2 1 0 0 1 1 1 1 PTHB1 C-terminus COMPASS-Shg1 PF05205.12 CDJ95737.1 - 0.34 11.6 3.9 0.42 11.3 0.6 2.4 2 1 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 LMBR1 PF04791.16 CDJ95737.1 - 1.2 8.0 5.3 1.6 7.5 5.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Ribosomal_L31e PF01198.19 CDJ95738.1 - 3e-44 149.2 3.3 4.8e-44 148.5 3.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L31e Syja_N PF02383.18 CDJ95739.1 - 1.2e-73 248.2 0.0 1.6e-73 247.8 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 CDJ95739.1 - 1.3e-13 50.6 0.0 2.5e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase COX4 PF02936.14 CDJ95740.1 - 5e-35 120.5 0.0 6.4e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV bZIP_2 PF07716.15 CDJ95741.1 - 2.7e-10 40.2 17.5 2.7e-10 40.2 17.5 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CDJ95741.1 - 0.0022 18.0 13.5 0.0022 18.0 13.5 1.5 1 1 0 1 1 1 1 bZIP transcription factor CaM_binding PF07839.11 CDJ95741.1 - 0.12 13.2 7.3 0.14 12.9 7.3 1.1 1 0 0 1 1 1 0 Plant calmodulin-binding domain VIR_N PF15912.5 CDJ95741.1 - 0.55 9.8 4.1 0.63 9.6 4.1 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal DivIC PF04977.15 CDJ95741.1 - 0.8 9.5 9.4 0.22 11.3 5.4 2.0 1 1 1 2 2 2 0 Septum formation initiator DUF5320 PF17253.2 CDJ95741.1 - 2.6 9.2 4.5 34 5.6 0.1 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5320) TT_ORF1 PF02956.14 CDJ95741.1 - 3 6.4 8.3 3.6 6.2 8.3 1.0 1 0 0 1 1 1 0 TT viral orf 1 PhoLip_ATPase_C PF16212.5 CDJ95742.1 - 1e-58 199.1 21.7 1e-58 199.1 21.7 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CDJ95742.1 - 6.7e-18 64.1 1.9 2e-17 62.6 1.9 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CDJ95742.1 - 4.8e-12 45.8 0.0 1.2e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CDJ95742.1 - 1.5e-09 38.5 0.2 0.0053 17.1 0.0 3.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CDJ95742.1 - 2.3e-05 24.0 7.9 0.0001 21.9 0.0 3.3 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CDJ95742.1 - 0.0019 18.0 0.3 0.0055 16.5 0.3 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3507 PF12015.8 CDJ95742.1 - 0.12 12.1 0.1 0.35 10.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) HEAT_2 PF13646.6 CDJ95743.1 - 6.5e-12 45.7 0.4 3.1e-05 24.3 0.5 4.3 2 1 2 4 4 4 3 HEAT repeats HEAT PF02985.22 CDJ95743.1 - 1.8e-11 43.3 4.7 0.0051 17.0 0.0 6.3 5 0 0 5 5 5 4 HEAT repeat Cnd1 PF12717.7 CDJ95743.1 - 6.1e-07 29.6 4.3 0.00026 21.1 0.1 3.7 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 CDJ95743.1 - 2.1e-05 23.9 3.3 0.28 10.3 0.1 3.3 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain HEAT_PBS PF03130.16 CDJ95743.1 - 0.0048 17.4 0.2 0.42 11.4 0.1 4.3 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat RTP1_C1 PF10363.9 CDJ95743.1 - 0.024 14.8 0.2 23 5.2 0.0 3.8 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 GCP_C_terminal PF04130.13 CDJ95743.1 - 0.029 13.8 0.0 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 Gamma tubulin complex component C-terminal HEAT_EZ PF13513.6 CDJ95743.1 - 1.5 9.4 6.1 29 5.3 0.0 4.1 4 0 0 4 4 4 0 HEAT-like repeat Sld5 PF05916.11 CDJ95746.1 - 2.7e-17 63.2 0.0 3.6e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein FKBP_C PF00254.28 CDJ95747.1 - 1.2e-34 118.5 0.0 1.3e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Asp PF00026.23 CDJ95750.1 - 3.8e-49 167.8 0.0 4.4e-49 167.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ95750.1 - 3.5e-06 27.4 0.1 0.037 14.3 0.0 2.2 1 1 0 2 2 2 2 Xylanase inhibitor N-terminal Il13Ra_Ig PF18001.1 CDJ95750.1 - 0.037 14.1 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 Interleukin-13 receptor subunit alpha Ig-like domain Asp PF00026.23 CDJ95751.1 - 7e-13 48.7 0.1 9.2e-13 48.3 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ95751.1 - 5.4e-06 26.8 0.1 7.1e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal PGF-CTERM PF18204.1 CDJ95751.1 - 1.6 8.8 4.9 2.8 8.0 4.9 1.4 1 0 0 1 1 1 0 PGF-CTERM motif Asp PF00026.23 CDJ95752.1 - 1.3e-76 258.1 3.0 1.5e-76 257.8 3.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ95752.1 - 5.3e-16 59.4 3.0 1.4e-07 32.0 2.1 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Col_cuticle_N PF01484.17 CDJ95753.1 - 1.5e-11 44.1 0.8 2e-11 43.8 0.8 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ95753.1 - 0.00015 21.5 37.1 0.00015 21.5 37.1 4.4 1 1 2 3 3 3 2 Collagen triple helix repeat (20 copies) PMBR PF09373.10 CDJ95754.1 - 0.015 15.5 0.0 0.13 12.4 0.0 2.5 2 0 0 2 2 2 0 Pseudomurein-binding repeat DUF5638 PF18688.1 CDJ95754.1 - 0.055 13.8 0.0 1.3 9.4 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5638) Mak16 PF04874.14 CDJ95754.1 - 0.57 10.8 18.5 0.064 13.9 2.3 3.2 3 1 1 4 4 4 0 Mak16 protein C-terminal region ABC2_membrane PF01061.24 CDJ95755.1 - 1e-10 41.4 7.0 1e-10 41.4 7.0 2.0 2 0 0 2 2 2 2 ABC-2 type transporter ABC2_membrane_3 PF12698.7 CDJ95755.1 - 0.031 13.4 9.1 0.09 11.9 9.2 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF4199 PF13858.6 CDJ95757.1 - 0.038 14.4 0.0 0.058 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Ras PF00071.22 CDJ95760.1 - 6.6e-08 32.3 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Ras family Zip PF02535.22 CDJ95761.1 - 9.8e-47 159.8 9.4 1.2e-46 159.4 9.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DctQ PF04290.12 CDJ95761.1 - 0.0099 15.8 0.4 0.0099 15.8 0.4 2.5 2 1 0 2 2 2 1 Tripartite ATP-independent periplasmic transporters, DctQ component SieB PF14163.6 CDJ95761.1 - 0.43 10.1 1.3 3.9 6.9 0.1 2.7 3 0 0 3 3 3 0 Super-infection exclusion protein B DUF1282 PF06930.12 CDJ95761.1 - 1.4 8.7 7.1 0.64 9.8 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1282) DUF4131 PF13567.6 CDJ95761.1 - 1.7 8.3 5.0 12 5.5 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SelP_N PF04592.14 CDJ95761.1 - 2.5 7.5 9.8 3.6 6.9 9.8 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF3792 PF12670.7 CDJ95761.1 - 3.1 8.0 14.6 0.66 10.2 4.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) EGF_2 PF07974.13 CDJ95762.1 - 1.7 9.1 6.0 3.6 8.1 6.0 1.6 1 0 0 1 1 1 0 EGF-like domain IncF PF17626.2 CDJ95763.1 - 0.016 15.5 0.3 0.022 15.1 0.3 1.2 1 0 0 1 1 1 0 Inclusion membrane protein F DAO PF01266.24 CDJ95764.1 - 2e-44 152.6 0.0 2.7e-44 152.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 CDJ95764.1 - 1.1e-41 141.7 0.1 2.2e-41 140.6 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 CDJ95764.1 - 5.4e-09 35.6 0.4 0.00027 20.1 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 CDJ95764.1 - 0.00019 20.9 0.4 0.0059 16.0 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 CDJ95764.1 - 0.00092 18.4 0.1 0.042 12.9 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 CDJ95764.1 - 0.0041 16.4 0.4 0.016 14.5 0.4 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_47 PF01532.20 CDJ95765.1 - 4.2e-150 500.6 2.1 4.9e-150 500.4 2.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AAA_2 PF07724.14 CDJ95766.1 - 3.9e-40 137.8 0.0 6.2e-40 137.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 CDJ95766.1 - 2.2e-14 54.0 0.0 5.2e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CDJ95766.1 - 2.2e-09 37.2 0.0 5.1e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CDJ95766.1 - 9.5e-08 32.1 0.0 7.6e-07 29.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MCM PF00493.23 CDJ95766.1 - 1.3e-05 24.5 0.0 3.2e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 MCM P-loop domain AAA_22 PF13401.6 CDJ95766.1 - 1.3e-05 25.5 0.4 6.1e-05 23.3 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CDJ95766.1 - 2e-05 24.2 0.1 0.00027 20.5 0.0 2.4 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_16 PF13191.6 CDJ95766.1 - 4.6e-05 23.9 1.6 0.0021 18.4 0.0 3.0 3 1 1 4 4 3 1 AAA ATPase domain Sigma54_activat PF00158.26 CDJ95766.1 - 9.1e-05 22.2 0.1 0.0014 18.4 0.1 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 CDJ95766.1 - 0.00011 21.7 1.0 0.042 13.2 0.1 2.8 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CDJ95766.1 - 0.0008 19.5 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CDJ95766.1 - 0.0017 18.2 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 CDJ95766.1 - 0.0032 17.2 0.4 0.018 14.8 0.1 2.3 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_8 PF12780.7 CDJ95766.1 - 0.0043 16.4 0.0 0.017 14.5 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_25 PF13481.6 CDJ95766.1 - 0.0044 16.6 0.0 0.0089 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CDJ95766.1 - 0.009 15.7 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CDJ95766.1 - 0.015 15.8 0.0 0.034 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CDJ95766.1 - 0.038 14.0 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CbiA PF01656.23 CDJ95766.1 - 0.041 13.9 0.0 0.12 12.5 0.0 1.9 1 1 1 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain PduV-EutP PF10662.9 CDJ95766.1 - 0.08 12.7 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation T7SS_ESX_EspC PF10824.8 CDJ95766.1 - 0.083 13.4 0.1 2.7 8.5 0.0 2.6 1 1 1 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm AAA_28 PF13521.6 CDJ95766.1 - 0.085 13.1 0.1 1.9 8.7 0.1 2.2 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 CDJ95766.1 - 0.11 13.1 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 CDJ95766.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 CDJ95766.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 CDJ95766.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF1421 PF07223.11 CDJ95766.1 - 0.14 12.0 0.2 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 UBA-like domain (DUF1421) NACHT PF05729.12 CDJ95766.1 - 0.33 10.9 1.4 0.72 9.7 0.0 2.3 3 0 0 3 3 3 0 NACHT domain Tom22 PF04281.13 CDJ95767.1 - 7.7e-12 45.2 0.1 9.5e-12 44.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Ran_BP1 PF00638.18 CDJ95768.1 - 5e-72 239.9 20.5 5.8e-40 136.3 3.8 2.8 3 0 0 3 3 3 2 RanBP1 domain WH1 PF00568.23 CDJ95768.1 - 6.6e-08 32.5 1.1 0.0096 15.8 0.3 2.5 2 0 0 2 2 2 2 WH1 domain Skp1 PF01466.19 CDJ95769.1 - 2.9e-30 104.1 1.0 5.5e-30 103.2 1.0 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 CDJ95769.1 - 1.5e-18 66.7 0.1 3.8e-18 65.4 0.1 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Myb_DNA-binding PF00249.31 CDJ95769.1 - 0.13 12.5 0.7 18 5.6 0.3 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain zf-C4 PF00105.18 CDJ95770.1 - 1.1e-27 96.3 12.8 1.9e-27 95.5 12.8 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ95770.1 - 8.6e-06 25.5 0.2 2e-05 24.3 0.2 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor fn3 PF00041.21 CDJ95771.1 - 1.4e-19 70.2 4.3 8.9e-10 38.8 0.5 3.6 3 0 0 3 3 3 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CDJ95771.1 - 1.1e-08 35.5 4.9 0.0061 17.1 0.6 3.6 4 0 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain Big_5 PF13205.6 CDJ95771.1 - 0.0021 18.8 6.6 0.33 11.7 1.7 3.6 1 1 2 3 3 3 2 Bacterial Ig-like domain Ig_3 PF13927.6 CDJ95771.1 - 0.021 15.4 2.2 0.91 10.2 0.0 3.6 4 1 1 5 5 5 0 Immunoglobulin domain Exo_endo_phos PF03372.23 CDJ95772.1 - 0.032 13.8 0.0 0.051 13.1 0.0 1.4 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CDJ95772.1 - 0.035 14.0 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase zf-C2H2 PF00096.26 CDJ95773.1 - 2.6e-08 33.8 21.0 0.00011 22.5 2.2 4.1 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ95773.1 - 5.3e-06 26.6 1.2 5.3e-06 26.6 1.2 3.8 4 1 0 4 4 3 1 Zinc-finger double domain zf-met PF12874.7 CDJ95773.1 - 0.00065 20.0 4.6 0.00065 20.0 4.6 2.8 3 0 0 3 3 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDJ95773.1 - 0.0013 18.9 3.1 0.0013 18.9 3.1 3.5 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CDJ95773.1 - 0.0032 17.8 4.6 0.014 15.8 0.4 2.3 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CDJ95773.1 - 0.015 16.1 16.6 0.031 15.1 0.8 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CDJ95773.1 - 0.039 13.7 3.5 0.039 13.7 3.5 3.7 3 1 1 4 4 3 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 CDJ95773.1 - 0.048 13.7 15.6 0.075 13.1 3.0 3.6 3 1 1 4 4 4 0 C2H2-type zinc finger Actin_micro PF17003.5 CDJ95773.1 - 0.071 12.3 2.7 4.5 6.4 0.6 2.1 2 0 0 2 2 2 0 Putative actin-like family zf_C2H2_ZHX PF18387.1 CDJ95773.1 - 0.27 10.9 1.9 4.2 7.1 0.1 2.3 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HE PF16278.5 CDJ95773.1 - 0.34 11.4 0.1 0.34 11.4 0.1 2.8 3 1 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger C1_2 PF03107.16 CDJ95773.1 - 0.48 10.8 6.0 2 8.8 0.3 2.6 2 1 0 2 2 2 0 C1 domain zf_UBZ PF18439.1 CDJ95773.1 - 0.93 9.1 4.5 11 5.7 0.1 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Exo_endo_phos_2 PF14529.6 CDJ95774.1 - 8.1e-10 38.6 0.0 1.7e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ95774.1 - 5.8e-09 35.8 0.0 1.4e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RT_RNaseH PF17917.1 CDJ95776.1 - 1.6e-31 108.7 0.0 4.7e-31 107.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ95776.1 - 2.4e-31 107.7 0.0 9.1e-31 105.9 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ95776.1 - 1.5e-28 99.8 0.0 2.5e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDJ95776.1 - 4.2e-17 62.4 0.0 2.1e-16 60.2 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ95776.1 - 1.3e-15 57.3 0.7 3.2e-15 56.0 0.7 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 CDJ95776.1 - 0.00064 20.2 0.1 0.0018 18.8 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve_3 PF13683.6 CDJ95776.1 - 0.018 14.8 0.0 0.076 12.8 0.0 2.1 1 0 0 1 1 1 0 Integrase core domain zf-H2C2 PF09337.10 CDJ95776.1 - 0.15 12.3 0.1 0.51 10.6 0.1 2.0 1 0 0 1 1 1 0 H2C2 zinc finger MRPL52 PF18699.1 CDJ95776.1 - 0.88 9.8 2.9 1.2 9.4 0.6 2.4 3 0 0 3 3 3 0 Mitoribosomal protein mL52 DUF148 PF02520.17 CDJ95778.1 - 3e-05 24.1 0.0 3.2e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 Mito_carr PF00153.27 CDJ95779.1 - 2.1e-20 72.4 0.2 7.5e-18 64.3 0.0 2.6 2 0 0 2 2 2 2 Mitochondrial carrier protein PWWP PF00855.17 CDJ95779.1 - 0.0091 16.4 0.5 0.025 15.0 0.4 1.8 1 1 1 2 2 2 1 PWWP domain Swi3 PF07962.12 CDJ95780.1 - 1.4e-23 82.7 0.0 2.7e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Alb1 PF09135.11 CDJ95780.1 - 0.13 13.1 2.5 1.3 9.9 1.7 2.2 2 0 0 2 2 2 0 Alb1 Exo_endo_phos_2 PF14529.6 CDJ95781.1 - 3.2e-08 33.4 0.0 1.4e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 CDJ95781.1 - 0.00058 19.4 0.1 0.0012 18.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Aminotran_1_2 PF00155.21 CDJ95782.1 - 7.1e-25 87.9 0.1 2e-14 53.5 0.1 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II Na_Ca_ex PF01699.24 CDJ95783.1 - 5.5e-26 91.3 15.9 5.5e-26 91.3 15.9 1.6 2 0 0 2 2 2 1 Sodium/calcium exchanger protein DUF3967 PF13152.6 CDJ95785.1 - 1.1 9.0 3.4 2.7 7.8 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3967) Vps51 PF08700.11 CDJ95786.1 - 2.5e-09 37.1 0.9 1.1e-08 35.1 0.9 2.2 1 0 0 1 1 1 1 Vps51/Vps67 Snf7 PF03357.21 CDJ95786.1 - 0.017 14.7 0.2 0.042 13.4 0.2 1.6 1 0 0 1 1 1 0 Snf7 Mst1_SARAH PF11629.8 CDJ95786.1 - 0.18 11.9 1.9 0.54 10.4 1.0 2.3 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 DUF3322 PF11795.8 CDJ95786.1 - 0.23 11.5 2.1 8.3 6.4 0.6 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) PAS_4 PF08448.10 CDJ95786.1 - 0.7 10.2 2.6 2.1 8.6 0.8 2.5 2 1 1 3 3 3 0 PAS fold PITH PF06201.13 CDJ95787.1 - 9.2e-36 123.3 0.2 1.6e-35 122.6 0.2 1.4 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 CDJ95787.1 - 7.2e-28 96.6 0.2 1.5e-27 95.6 0.2 1.5 1 0 0 1 1 1 1 Thioredoxin SH3_9 PF14604.6 CDJ95787.1 - 1.4e-25 88.8 0.1 1.5e-11 43.9 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 CDJ95787.1 - 5e-23 80.4 0.0 1.1e-13 50.5 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 CDJ95787.1 - 1.2e-17 63.3 0.1 8.8e-08 31.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Thioredoxin_2 PF13098.6 CDJ95787.1 - 2.2e-06 28.1 0.1 1.1e-05 25.9 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CDJ95787.1 - 1.3e-05 25.3 0.1 3.9e-05 23.8 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 CDJ95787.1 - 0.00038 20.2 0.6 0.0047 16.7 0.1 2.6 2 1 1 3 3 3 1 Thioredoxin Thioredoxin_8 PF13905.6 CDJ95787.1 - 0.00057 20.2 0.0 0.0015 18.8 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 CDJ95787.1 - 0.0065 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Redoxin OST3_OST6 PF04756.13 CDJ95787.1 - 0.0099 15.3 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family ABC_tran_CTD PF16326.5 CDJ95787.1 - 0.051 13.8 0.2 0.15 12.3 0.2 1.8 1 0 0 1 1 1 0 ABC transporter C-terminal domain AhpC-TSA PF00578.21 CDJ95787.1 - 0.055 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Lzipper-MIP1 PF14389.6 CDJ95787.1 - 0.09 13.1 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Rhamno_transf PF11316.8 CDJ95787.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative rhamnosyl transferase NNMT_PNMT_TEMT PF01234.17 CDJ95789.1 - 4.4e-47 160.4 0.0 5.4e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Pox_MCEL PF03291.16 CDJ95789.1 - 0.0034 16.5 0.0 0.0037 16.4 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Surp PF01805.20 CDJ95790.1 - 1.5e-23 82.5 0.7 6.8e-13 48.4 0.1 2.4 2 0 0 2 2 2 2 Surp module DRY_EERY PF09750.9 CDJ95790.1 - 7e-09 36.1 1.0 3.2e-06 27.5 1.1 5.0 4 1 1 5 5 5 2 Alternative splicing regulator zf-C2H2 PF00096.26 CDJ95791.1 - 0.0014 19.0 17.2 0.038 14.5 1.4 4.3 4 0 0 4 4 4 2 Zinc finger, C2H2 type Collagen PF01391.18 CDJ95791.1 - 0.0016 18.2 14.6 0.0016 18.2 14.6 2.4 3 0 0 3 3 3 1 Collagen triple helix repeat (20 copies) zf-C2H2_4 PF13894.6 CDJ95791.1 - 0.0084 16.9 15.9 0.11 13.4 0.5 4.3 5 0 0 5 5 5 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 CDJ95791.1 - 0.24 11.1 4.3 0.13 11.9 0.3 2.2 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Cytochrome_C554 PF13435.6 CDJ95791.1 - 1.3 10.0 4.6 0.55 11.2 0.4 2.4 2 0 0 2 2 2 0 Cytochrome c554 and c-prime zf-C2H2_jaz PF12171.8 CDJ95791.1 - 1.7 9.0 6.2 2.2 8.7 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CDJ95791.1 - 6 7.3 7.1 23 5.4 7.1 2.0 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) 7tm_1 PF00001.21 CDJ95792.1 - 1.2e-07 31.3 12.9 1.7e-07 30.8 12.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PsbM PF05151.12 CDJ95792.1 - 0.2 11.5 2.4 0.73 9.7 2.4 1.9 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) DUF3989 PF13150.6 CDJ95792.1 - 0.33 10.7 2.7 7.4 6.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3989) 60KD_IMP PF02096.20 CDJ95792.1 - 0.39 10.6 6.2 0.029 14.3 0.9 1.9 2 0 0 2 2 2 0 60Kd inner membrane protein PARM PF17061.5 CDJ95793.1 - 0.049 13.8 28.7 0.082 13.0 28.7 1.3 1 0 0 1 1 1 0 PARM START PF01852.19 CDJ95794.1 - 2.5e-13 49.9 0.0 2.8e-13 49.7 0.0 1.0 1 0 0 1 1 1 1 START domain Mic1 PF07035.12 CDJ95795.1 - 1.2e-26 93.3 0.9 1.5e-26 93.0 0.9 1.1 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like DUF5071 PF16804.5 CDJ95795.1 - 0.0052 17.0 0.7 0.0085 16.3 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5071) DUF5615 PF18480.1 CDJ95795.1 - 0.069 12.9 0.2 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) MCR_beta PF02241.18 CDJ95795.1 - 0.19 11.3 0.1 0.22 11.1 0.1 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain zf-ANAPC11 PF12861.7 CDJ95796.1 - 6.8e-32 109.4 12.2 9.2e-32 109.0 12.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CDJ95796.1 - 7.5e-19 67.8 18.1 1.2e-18 67.2 18.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CDJ95796.1 - 0.00013 22.2 23.8 0.0029 17.9 23.8 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CDJ95796.1 - 0.14 12.0 16.7 0.38 10.7 16.7 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ95796.1 - 0.59 10.1 17.9 4.9 7.2 18.7 2.0 1 1 1 2 2 2 0 zinc-RING finger domain Pox_A_type_inc PF04508.12 CDJ95798.1 - 0.0061 16.4 1.4 12 5.9 0.4 4.9 3 0 0 3 3 3 1 Viral A-type inclusion protein repeat ZapB PF06005.12 CDJ95798.1 - 0.013 15.9 2.2 0.013 15.9 2.2 9.6 7 3 3 10 10 10 0 Cell division protein ZapB G0-G1_switch_2 PF15103.6 CDJ95798.1 - 0.067 13.6 0.1 0.067 13.6 0.1 6.4 4 2 1 6 6 6 0 G0/G1 switch protein 2 zf-CCHC PF00098.23 CDJ95799.1 - 7.3e-06 25.8 0.7 1.4e-05 25.0 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 CDJ95799.1 - 0.18 12.5 0.0 0.58 10.8 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease Ion_trans_2 PF07885.16 CDJ95800.1 - 1.6e-15 56.8 3.6 2.5e-15 56.2 3.6 1.3 1 0 0 1 1 1 1 Ion channel Asp PF00026.23 CDJ95802.1 - 2.8e-90 302.9 4.7 3.5e-90 302.6 4.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ95802.1 - 4.4e-11 43.3 8.0 4.4e-11 43.3 5.5 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ95802.1 - 9.4e-05 22.2 0.0 0.00027 20.7 0.0 1.8 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CDJ95802.1 - 0.0011 19.6 0.2 1 10.0 0.0 3.1 3 0 0 3 3 3 2 Aspartyl protease Ion_trans_2 PF07885.16 CDJ95803.1 - 4.8e-36 122.6 18.3 3.3e-18 65.4 2.7 2.1 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 CDJ95803.1 - 4.3e-06 26.1 10.6 0.0039 16.4 4.2 2.3 1 1 1 2 2 2 2 Ion transport protein DUF2178 PF09946.9 CDJ95803.1 - 0.00074 19.7 0.5 0.026 14.7 0.0 2.2 1 1 1 2 2 2 1 Predicted membrane protein (DUF2178) EMP70 PF02990.16 CDJ95803.1 - 0.51 8.9 5.5 7.7 5.1 0.1 2.0 2 0 0 2 2 2 0 Endomembrane protein 70 DUF2975 PF11188.8 CDJ95803.1 - 2.8 7.8 7.0 0.78 9.6 0.4 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2975) DUF3629 PF12302.8 CDJ95804.1 - 0.012 15.1 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) IL2 PF00715.17 CDJ95804.1 - 0.043 13.8 0.3 0.057 13.4 0.3 1.2 1 0 0 1 1 1 0 Interleukin 2 Sarcoglycan_2 PF05510.13 CDJ95805.1 - 8.1e-10 38.0 0.0 8.8e-10 37.9 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon ProQ PF04352.13 CDJ95805.1 - 0.19 11.6 0.2 0.69 9.8 0.2 1.8 1 1 1 2 2 2 0 ProQ/FINO family Pkinase PF00069.25 CDJ95807.1 - 4.8e-14 52.4 0.0 5.5e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ95807.1 - 6.8e-11 41.9 0.0 8.2e-11 41.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ95807.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Kinase-like HTH_48 PF17906.1 CDJ95808.1 - 4.2e-13 49.2 0.0 6.8e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_Tnp_IS630 PF01710.16 CDJ95808.1 - 0.012 15.6 0.1 0.015 15.4 0.1 1.1 1 0 0 1 1 1 0 Transposase HTH_32 PF13565.6 CDJ95808.1 - 0.061 13.9 0.0 0.08 13.6 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain rve PF00665.26 CDJ95809.1 - 2.6e-21 76.0 0.0 5.3e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ95809.1 - 6.8e-08 32.5 0.2 1.3e-07 31.6 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CDJ95809.1 - 4.9e-05 23.0 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain NHase_beta PF02211.15 CDJ95809.1 - 0.045 13.8 0.1 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Nitrile hydratase beta subunit RVT_1 PF00078.27 CDJ95810.1 - 1.3e-05 24.8 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lactamase_B PF00753.27 CDJ95813.1 - 4.4e-12 46.4 0.7 1.9e-10 41.1 0.7 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lustrin_cystein PF14625.6 CDJ95813.1 - 8.4e-06 26.1 1.8 1.5e-05 25.2 1.8 1.5 1 0 0 1 1 1 1 Lustrin, cysteine-rich repeated domain Lactamase_B_2 PF12706.7 CDJ95813.1 - 0.004 16.7 1.1 0.02 14.4 0.1 2.5 3 1 0 3 3 3 1 Beta-lactamase superfamily domain DUF3253 PF11625.8 CDJ95813.1 - 0.058 13.6 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) Acyl_transf_1 PF00698.21 CDJ95814.1 - 0.0039 16.7 0.0 0.0048 16.4 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain Peptidase_A17 PF05380.13 CDJ95815.1 - 1.9e-38 132.0 0.2 1.9e-38 132.0 0.2 1.9 2 0 0 2 2 2 1 Pao retrotransposon peptidase DUF1759 PF03564.15 CDJ95815.1 - 1e-20 74.2 2.9 2e-20 73.2 0.3 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) RVT_1 PF00078.27 CDJ95815.1 - 2.2e-09 37.1 0.0 5.3e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CDJ95815.1 - 1.7e-07 31.8 0.0 4.5e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ95815.1 - 2.5e-07 31.2 0.0 6.9e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RL11D PF11088.8 CDJ95815.1 - 0.0047 17.2 0.0 0.35 11.2 0.0 3.6 3 0 0 3 3 3 1 Glycoprotein encoding membrane proteins RL5A and RL6 DUF1758 PF05585.12 CDJ95815.1 - 0.009 15.8 0.0 0.046 13.5 0.0 2.2 2 0 0 2 2 2 1 Putative peptidase (DUF1758) RVP PF00077.20 CDJ95815.1 - 0.055 13.8 0.0 0.18 12.1 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease Acyl_transf_1 PF00698.21 CDJ95816.1 - 4.9e-19 69.0 0.1 6.7e-19 68.5 0.1 1.2 1 0 0 1 1 1 1 Acyl transferase domain ADP_PFK_GK PF04587.15 CDJ95817.1 - 3.3e-14 52.3 0.0 4.3e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region DUF4534 PF15049.6 CDJ95817.1 - 0.057 13.2 0.6 0.082 12.7 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4534) LUC7 PF03194.15 CDJ95818.1 - 2.8e-77 259.8 16.3 2.8e-77 259.8 16.3 1.9 1 1 1 2 2 2 1 LUC7 N_terminus DUF3053 PF11254.8 CDJ95818.1 - 1.2 8.7 6.2 0.12 11.9 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) DUF2793 PF10983.8 CDJ95820.1 - 0.099 12.5 0.1 7.6 6.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2793) Ly49 PF08391.10 CDJ95820.1 - 0.71 10.2 3.7 1.7 9.0 3.7 1.6 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region rve PF00665.26 CDJ95821.1 - 3.2e-23 82.2 0.0 6e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ95821.1 - 1.8e-08 34.4 1.5 3.3e-08 33.5 1.5 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CDJ95821.1 - 0.0011 18.7 0.0 0.003 17.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CDJ95821.1 - 0.15 12.3 1.6 0.25 11.6 0.1 2.0 2 0 0 2 2 2 0 H2C2 zinc finger G0-G1_switch_2 PF15103.6 CDJ95823.1 - 0.076 13.5 0.4 0.16 12.4 0.3 1.6 1 1 0 1 1 1 0 G0/G1 switch protein 2 DUF687 PF05095.12 CDJ95823.1 - 0.11 11.0 0.1 0.15 10.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF687) DUF4519 PF15012.6 CDJ95823.1 - 1.5 9.1 9.4 1.9 8.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) DOMON PF03351.17 CDJ95824.1 - 5.4e-12 46.0 0.0 4.6e-11 43.0 0.0 2.3 3 0 0 3 3 3 1 DOMON domain eIF-3_zeta PF05091.12 CDJ95825.1 - 8.8e-181 602.4 0.0 1e-180 602.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) GMC_oxred_C PF05199.13 CDJ95825.1 - 1.1e-39 136.2 0.2 1.9e-39 135.4 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 CDJ95825.1 - 2e-08 34.0 0.7 3.4e-08 33.2 0.2 1.7 2 0 0 2 2 2 1 GMC oxidoreductase NARG2_C PF10505.9 CDJ95825.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated gene protein 2 C-terminus GMC_oxred_N PF00732.19 CDJ95826.1 - 1.9e-63 214.6 0.0 2.3e-63 214.4 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 CDJ95826.1 - 0.00015 21.0 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 CDJ95826.1 - 0.00025 21.2 0.0 0.0006 20.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CDJ95826.1 - 0.0059 16.2 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CDJ95826.1 - 0.0086 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 CDJ95826.1 - 0.0098 15.2 0.1 0.027 13.7 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 CDJ95826.1 - 0.011 15.0 0.0 0.022 14.0 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 CDJ95826.1 - 0.012 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 CDJ95826.1 - 0.057 12.1 0.0 0.077 11.7 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 CDJ95826.1 - 0.2 10.9 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PIF1 PF05970.14 CDJ95829.1 - 5.6e-99 331.7 0.0 7.4e-99 331.4 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 CDJ95829.1 - 7.7e-64 215.4 0.0 1.6e-63 214.4 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 CDJ95829.1 - 9.3e-12 45.1 0.0 1.5e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ95829.1 - 1.3e-05 25.6 0.0 2.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 CDJ95829.1 - 3e-05 22.2 0.0 6.8e-05 21.0 0.0 1.5 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 CDJ95829.1 - 0.00018 21.4 0.0 1 9.0 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 CDJ95829.1 - 0.00041 20.1 0.0 0.0013 18.5 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ResIII PF04851.15 CDJ95829.1 - 0.005 16.9 0.0 0.015 15.3 0.0 1.7 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Phage_GPA PF05840.13 CDJ95829.1 - 0.0062 15.7 0.0 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Bacteriophage replication gene A protein (GPA) AAA_16 PF13191.6 CDJ95829.1 - 0.0097 16.3 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDJ95829.1 - 0.01 16.1 0.0 0.033 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CDJ95829.1 - 0.023 13.7 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 CDJ95829.1 - 0.027 14.4 0.1 0.12 12.3 0.1 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 CDJ95829.1 - 0.044 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2791 PF10923.8 CDJ95829.1 - 0.14 11.0 0.0 0.71 8.6 0.0 1.9 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) Amidohydro_1 PF01979.20 CDJ95830.1 - 1.8e-19 70.2 0.8 2.6e-19 69.8 0.8 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CDJ95830.1 - 9e-09 35.3 0.1 1.5e-08 34.5 0.1 1.4 1 0 0 1 1 1 1 Amidohydrolase family Aa_trans PF01490.18 CDJ95831.1 - 3.7e-84 282.8 26.5 4.4e-84 282.6 26.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PSI_PSAK PF01241.18 CDJ95831.1 - 0.01 15.8 3.5 0.049 13.6 0.5 2.9 2 0 0 2 2 2 0 Photosystem I psaG / psaK PEN-2 PF10251.9 CDJ95831.1 - 0.19 12.2 2.5 0.32 11.4 0.2 2.6 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase EGF_2 PF07974.13 CDJ95832.1 - 5.8e-19 68.1 136.4 0.0013 19.1 13.0 8.9 8 0 0 8 8 8 8 EGF-like domain Tox-GHH PF15636.6 CDJ95832.1 - 3.2e-08 33.4 1.6 7.1e-08 32.3 1.6 1.5 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin RHS_repeat PF05593.14 CDJ95832.1 - 8.2e-08 32.6 22.7 0.14 12.8 0.1 8.9 8 1 0 8 8 8 3 RHS Repeat NHL PF01436.21 CDJ95832.1 - 1.3e-07 31.3 0.0 0.057 13.5 0.0 4.6 4 0 0 4 4 4 2 NHL repeat I-EGF_1 PF18372.1 CDJ95832.1 - 0.055 13.6 0.1 0.055 13.6 0.1 8.4 8 0 0 8 8 8 0 Integrin beta epidermal growth factor like domain 1 EGF PF00008.27 CDJ95832.1 - 1.6 9.1 110.5 0.27 11.6 7.4 8.9 9 0 0 9 9 9 0 EGF-like domain Fer2 PF00111.27 CDJ95834.1 - 5.5e-14 51.9 1.5 2.1e-06 27.6 0.1 2.4 2 0 0 2 2 2 2 2Fe-2S iron-sulfur cluster binding domain zf-RING_7 PF02591.15 CDJ95834.1 - 0.0028 17.8 0.4 4.7 7.5 0.0 3.3 3 0 0 3 3 3 2 C4-type zinc ribbon domain zf-CXXC PF02008.20 CDJ95834.1 - 0.011 15.7 1.1 3.3 7.8 0.1 2.5 2 0 0 2 2 2 0 CXXC zinc finger domain muHD PF10291.9 CDJ95834.1 - 0.24 10.8 0.0 0.39 10.1 0.0 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Fer2 PF00111.27 CDJ95835.1 - 4.7e-05 23.3 0.1 8.3e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Motile_Sperm PF00635.26 CDJ95836.1 - 3e-20 72.1 0.0 4.5e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain AAA PF00004.29 CDJ95837.1 - 2.4e-40 138.0 1.2 5.9e-40 136.7 0.1 2.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 CDJ95837.1 - 2.1e-08 34.5 1.0 6.7e-07 29.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 CDJ95837.1 - 2.4e-08 33.7 0.6 7e-08 32.1 0.1 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 CDJ95837.1 - 9.2e-07 29.4 0.5 3.4e-05 24.3 0.2 2.9 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CDJ95837.1 - 1.6e-05 25.2 1.8 0.0096 16.2 0.1 2.9 3 1 1 4 4 2 2 AAA domain RuvB_N PF05496.12 CDJ95837.1 - 4.2e-05 23.3 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CDJ95837.1 - 4.4e-05 24.0 0.2 0.00057 20.4 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.14 CDJ95837.1 - 0.00013 22.0 0.9 0.0012 18.8 0.3 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CDJ95837.1 - 0.0015 18.5 0.0 0.006 16.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CDJ95837.1 - 0.0057 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 CDJ95837.1 - 0.008 15.9 0.2 0.05 13.3 0.2 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain ATPase PF06745.13 CDJ95837.1 - 0.011 15.1 0.4 0.21 10.9 0.1 2.4 1 1 1 2 2 2 0 KaiC MCM PF00493.23 CDJ95837.1 - 0.011 14.8 0.2 1.3 8.1 0.0 2.4 2 0 0 2 2 2 0 MCM P-loop domain NACHT PF05729.12 CDJ95837.1 - 0.013 15.4 0.2 0.28 11.1 0.0 2.4 1 1 1 2 2 2 0 NACHT domain RNA_helicase PF00910.22 CDJ95837.1 - 0.018 15.4 0.0 0.089 13.2 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 CDJ95837.1 - 0.019 14.7 0.1 0.058 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CDJ95837.1 - 0.039 13.2 0.2 0.77 8.9 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_3 PF07726.11 CDJ95837.1 - 0.047 13.6 0.0 0.095 12.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CDJ95837.1 - 0.049 13.0 0.0 0.09 12.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 CDJ95837.1 - 0.056 12.6 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 CDJ95837.1 - 0.062 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Bac_DnaA PF00308.18 CDJ95837.1 - 0.087 12.6 0.1 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein TsaE PF02367.17 CDJ95837.1 - 0.094 12.7 0.1 0.26 11.3 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 CDJ95837.1 - 0.12 11.6 0.0 0.31 10.3 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 CDJ95837.1 - 0.14 11.7 0.3 0.55 9.8 0.2 1.9 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.6 CDJ95837.1 - 0.21 11.9 0.3 0.46 10.7 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CDJ95837.1 - 0.62 9.8 4.6 0.29 10.8 0.4 2.5 3 1 0 3 3 3 0 AAA domain Baculo_FP PF03258.14 CDJ95839.1 - 0.014 15.6 2.7 0.065 13.4 2.7 2.0 1 1 0 1 1 1 0 Baculovirus FP protein DUF2573 PF10835.8 CDJ95839.1 - 0.037 14.4 2.2 0.32 11.4 0.2 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF2573) Pre-PUA PF17832.1 CDJ95839.1 - 0.1 13.3 0.3 0.28 11.9 0.5 1.6 2 0 0 2 2 2 0 Pre-PUA-like domain Deltameth_res PF16020.5 CDJ95840.1 - 7.2e-13 48.2 0.8 8.4e-13 48.0 0.1 1.4 2 0 0 2 2 2 1 Deltamethrin resistance DUF45 PF01863.17 CDJ95841.1 - 0.087 12.9 0.2 0.17 11.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 RRM_1 PF00076.22 CDJ95842.1 - 7.7e-20 70.5 0.0 1.6e-15 56.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ95842.1 - 2.9e-08 33.7 0.0 0.00025 21.1 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif NAGLU_N PF12971.7 CDJ95842.1 - 0.18 11.6 0.0 3.2 7.6 0.0 2.1 2 0 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain RNA_polI_A14 PF08203.11 CDJ95843.1 - 0.12 13.2 0.7 0.23 12.2 0.2 1.7 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 AT_hook PF02178.19 CDJ95843.1 - 2.1 8.5 22.9 0.64 10.1 4.7 2.5 2 0 0 2 2 2 0 AT hook motif Collagen PF01391.18 CDJ95844.1 - 3.7e-25 87.4 101.5 2.7e-10 39.9 34.4 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ95844.1 - 2e-15 56.6 2.7 2.6e-15 56.2 2.7 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ95845.1 - 2.1e-25 88.2 104.3 3.9e-09 36.1 29.9 4.2 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ95845.1 - 1.5e-10 40.9 2.3 2e-10 40.6 2.3 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain AAA_9 PF12781.7 CDJ95847.1 - 2.3e-73 246.0 0.2 1.6e-71 240.0 0.1 2.9 3 0 0 3 3 3 1 ATP-binding dynein motor region Dynein_C PF18199.1 CDJ95847.1 - 1.2e-41 143.0 0.0 2.2e-41 142.1 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 CDJ95847.1 - 4e-34 117.8 0.0 6.7e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CDJ95847.1 - 3.1e-28 98.3 0.1 4.8e-27 94.4 0.0 3.0 4 0 0 4 4 4 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CDJ95847.1 - 0.14 11.1 0.0 0.14 11.1 0.0 1.7 2 0 0 2 2 2 0 Microtubule-binding stalk of dynein motor CENP-H PF05837.12 CDJ95847.1 - 9.3 6.7 7.0 25 5.3 0.0 3.0 3 1 0 3 3 3 0 Centromere protein H (CENP-H) DHC_N1 PF08385.12 CDJ95848.1 - 6.2e-16 58.1 0.1 9e-16 57.6 0.1 1.2 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 DNase_II PF03265.15 CDJ95850.1 - 2.1e-93 313.2 0.0 2.4e-93 313.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II His_Phos_2 PF00328.22 CDJ95851.1 - 9.1e-08 31.8 0.1 6e-05 22.6 0.0 2.5 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Orf78 PF06024.12 CDJ95851.1 - 0.0015 18.8 0.0 0.0028 17.9 0.0 1.3 1 0 0 1 1 1 1 Orf78 (ac78) DUF4366 PF14283.6 CDJ95851.1 - 0.0021 18.1 0.2 0.0033 17.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) CrgA PF06781.12 CDJ95851.1 - 0.071 13.2 0.1 0.2 11.7 0.1 1.8 1 0 0 1 1 1 0 Cell division protein CrgA KinB_sensor PF16767.5 CDJ95853.1 - 0.032 14.7 0.1 0.15 12.5 0.1 2.1 2 0 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB HA2 PF04408.23 CDJ95854.1 - 3.5e-19 69.1 1.3 7.9e-19 67.9 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDJ95854.1 - 5.9e-15 55.4 0.0 2.1e-14 53.6 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDJ95854.1 - 1.9e-11 44.3 0.0 2.8e-10 40.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ95854.1 - 7.9e-10 38.8 0.0 2e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDJ95854.1 - 0.00026 21.3 1.9 0.0007 19.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain ATPase PF06745.13 CDJ95854.1 - 0.006 16.0 0.1 0.025 13.9 0.0 2.0 2 0 0 2 2 2 1 KaiC AAA_30 PF13604.6 CDJ95854.1 - 0.02 14.6 0.0 0.07 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain DnaJ-X PF14308.6 CDJ95854.1 - 0.058 12.8 0.1 0.058 12.8 0.1 2.3 2 1 0 2 2 2 0 X-domain of DnaJ-containing AAA_23 PF13476.6 CDJ95854.1 - 0.12 12.8 0.1 0.12 12.8 0.1 2.9 3 0 0 3 3 3 0 AAA domain DUF4852 PF16144.5 CDJ95854.1 - 0.13 12.3 0.7 0.28 11.3 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4852) Peptidase_A17 PF05380.13 CDJ95855.1 - 4.4e-47 160.1 0.3 3.5e-46 157.2 0.1 2.3 2 0 0 2 2 2 1 Pao retrotransposon peptidase RVT_1 PF00078.27 CDJ95855.1 - 2.6e-08 33.6 0.0 5.4e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CBS PF00571.28 CDJ95856.1 - 0.029 14.8 0.1 0.072 13.5 0.0 1.7 2 0 0 2 2 2 0 CBS domain Stork_head PF10264.9 CDJ95857.1 - 7e-20 71.0 0.2 1.8e-19 69.7 0.2 1.6 2 0 0 2 2 2 1 Winged helix Storkhead-box1 domain DUF2690 PF10901.8 CDJ95857.1 - 0.19 12.1 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2690) Cast PF10174.9 CDJ95858.1 - 1.5e-45 155.7 89.2 2.9e-20 72.1 26.8 3.6 1 1 1 3 3 3 3 RIM-binding protein of the cytomatrix active zone DUF745 PF05335.13 CDJ95858.1 - 0.0098 15.6 16.5 0.0098 15.6 16.5 5.3 2 2 3 6 6 6 1 Protein of unknown function (DUF745) PhaC_N PF07167.13 CDJ95858.1 - 1.7 8.2 4.6 2 8.0 0.4 2.9 3 0 0 3 3 3 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus AAA_13 PF13166.6 CDJ95858.1 - 5 5.7 62.2 1.1 7.8 17.3 4.2 2 1 2 4 4 4 0 AAA domain Spc7 PF08317.11 CDJ95858.1 - 8.4 5.2 100.1 0.11 11.4 6.2 6.0 3 1 3 6 6 6 0 Spc7 kinetochore protein DUF1619 PF07773.11 CDJ95859.1 - 5.6e-15 56.1 4.1 8.3e-10 39.1 1.2 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1619) HTH_48 PF17906.1 CDJ95859.1 - 2.9e-11 43.3 0.1 6.5e-11 42.2 0.1 1.7 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 CDJ95859.1 - 0.0035 17.9 0.1 0.01 16.4 0.1 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_11 PF08279.12 CDJ95859.1 - 0.006 16.5 0.1 0.013 15.4 0.1 1.6 1 0 0 1 1 1 1 HTH domain GerE PF00196.19 CDJ95859.1 - 0.074 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 CDJ95859.1 - 0.088 12.5 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Transposase_1 PF01359.18 CDJ95859.1 - 0.1 12.4 0.0 9.6 6.1 0.0 2.8 2 0 0 2 2 2 0 Transposase (partial DDE domain) HTH_24 PF13412.6 CDJ95859.1 - 0.3 10.7 1.3 0.77 9.4 0.2 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Glyco_transf_43 PF03360.16 CDJ95860.1 - 2.1e-40 138.7 0.0 2.6e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 Peptidase_S80 PF07230.11 CDJ95861.1 - 0.0017 16.7 0.2 0.002 16.5 0.2 1.0 1 0 0 1 1 1 1 Bacteriophage T4-like capsid assembly protein (Gp20) DUF3788 PF12663.7 CDJ95861.1 - 0.065 13.2 0.2 0.12 12.3 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3788) BTB PF00651.31 CDJ95862.1 - 3.6e-16 59.4 1.8 6.6e-07 29.5 0.0 2.5 3 0 0 3 3 3 2 BTB/POZ domain DEAD PF00270.29 CDJ95863.1 - 6e-47 159.7 0.8 7.5e-47 159.3 0.8 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ95863.1 - 1e-08 35.4 0.0 1.3e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CDJ95863.1 - 2e-05 24.4 0.1 2.7e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ95863.1 - 0.00016 22.1 0.9 0.00024 21.5 0.9 1.4 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 CDJ95863.1 - 0.00047 20.1 0.1 0.00072 19.5 0.1 1.4 1 1 0 1 1 1 1 Helicase CMS1 PF14617.6 CDJ95863.1 - 0.0018 17.6 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 CDJ95863.1 - 0.0056 17.0 0.3 0.032 14.5 0.3 2.0 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 CDJ95863.1 - 0.012 15.6 0.5 0.052 13.5 0.5 1.9 1 1 0 1 1 1 0 Flavivirus DEAD domain UvrD-helicase PF00580.21 CDJ95863.1 - 0.081 12.4 0.1 0.14 11.7 0.1 1.3 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain DEAD PF00270.29 CDJ95865.1 - 6e-47 159.7 0.8 7.5e-47 159.3 0.8 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ95865.1 - 1e-08 35.4 0.0 1.3e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CDJ95865.1 - 2e-05 24.4 0.1 2.7e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ95865.1 - 0.00016 22.1 0.9 0.00024 21.5 0.9 1.4 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 CDJ95865.1 - 0.00047 20.1 0.1 0.00072 19.5 0.1 1.4 1 1 0 1 1 1 1 Helicase CMS1 PF14617.6 CDJ95865.1 - 0.0018 17.6 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 CDJ95865.1 - 0.0056 17.0 0.3 0.032 14.5 0.3 2.0 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 CDJ95865.1 - 0.012 15.6 0.5 0.052 13.5 0.5 1.9 1 1 0 1 1 1 0 Flavivirus DEAD domain UvrD-helicase PF00580.21 CDJ95865.1 - 0.081 12.4 0.1 0.14 11.7 0.1 1.3 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain RVT_1 PF00078.27 CDJ95866.1 - 3.8e-05 23.3 0.0 6.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_M32 PF02074.15 CDJ95866.1 - 0.023 13.5 0.2 0.2 10.4 0.4 2.0 2 0 0 2 2 2 0 Carboxypeptidase Taq (M32) metallopeptidase DDE_Tnp_1_7 PF13843.6 CDJ95868.1 - 0.00053 19.4 0.2 0.00065 19.1 0.2 1.1 1 0 0 1 1 1 1 Transposase IS4 Peptidase_C12 PF01088.21 CDJ95870.1 - 3.3e-75 252.4 0.0 1.4e-46 158.9 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 XPC-binding PF09280.11 CDJ95870.1 - 0.077 12.7 0.0 2.1 8.2 0.0 2.3 2 0 0 2 2 2 0 XPC-binding domain Thioredoxin PF00085.20 CDJ95871.1 - 1.4e-16 60.3 0.0 2.2e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Zip PF02535.22 CDJ95871.1 - 0.005 16.1 0.0 0.0067 15.7 0.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter OST3_OST6 PF04756.13 CDJ95871.1 - 0.035 13.5 0.0 0.06 12.7 0.0 1.5 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family UPF0220 PF05255.11 CDJ95871.1 - 0.088 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) Thioredoxin_2 PF13098.6 CDJ95871.1 - 0.13 12.7 0.2 0.49 10.9 0.2 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain Ank_5 PF13857.6 CDJ95872.1 - 5.4e-08 33.0 0.0 1.1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ95872.1 - 1.6e-06 28.6 0.0 2.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDJ95872.1 - 7.4e-06 25.9 0.0 3.2e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 CDJ95872.1 - 0.00011 22.5 0.0 0.00021 21.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 CDJ95872.1 - 0.00016 22.2 0.0 0.00035 21.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Methyltransf_31 PF13847.6 CDJ95873.1 - 1.2e-08 34.9 0.5 2.2e-08 34.0 0.5 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ95873.1 - 2.7e-08 34.4 0.1 6.9e-08 33.1 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ95873.1 - 4.5e-07 30.4 0.1 1.1e-06 29.1 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ95873.1 - 0.00017 22.3 0.1 0.00034 21.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 CDJ95873.1 - 0.00024 20.6 0.5 0.0065 15.9 0.2 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TehB Methyltransf_23 PF13489.6 CDJ95873.1 - 0.00038 20.3 0.0 0.0008 19.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Rsm22 PF09243.10 CDJ95873.1 - 0.00041 19.7 0.0 0.00078 18.8 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 CMAS PF02353.20 CDJ95873.1 - 0.00055 19.3 0.0 0.00078 18.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 CDJ95873.1 - 0.00059 19.6 0.0 0.00099 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CheR PF01739.18 CDJ95873.1 - 0.0051 16.3 0.2 0.009 15.5 0.2 1.4 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain DOT1 PF08123.13 CDJ95873.1 - 0.011 15.3 1.2 0.26 10.8 1.2 2.2 1 1 0 1 1 1 0 Histone methylation protein DOT1 CpXC PF14353.6 CDJ95873.1 - 0.043 13.9 0.2 0.22 11.6 0.1 2.1 2 0 0 2 2 2 0 CpXC protein PAP2 PF01569.21 CDJ95874.1 - 1.5e-28 99.3 4.4 1.5e-28 99.3 4.4 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 CDJ95874.1 - 6.3e-05 22.8 10.9 7.9e-05 22.4 7.5 2.5 1 1 0 2 2 2 1 PAP2 superfamily EMP70 PF02990.16 CDJ95874.1 - 0.2 10.3 5.4 0.34 9.5 5.4 1.3 1 0 0 1 1 1 0 Endomembrane protein 70 DUF2070 PF09843.9 CDJ95874.1 - 5.1 5.3 5.3 1.1 7.4 1.2 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) eIF-1a PF01176.19 CDJ95875.1 - 1.5e-17 63.1 0.2 2.3e-17 62.5 0.2 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 TFIIF_alpha PF05793.12 CDJ95875.1 - 0.011 14.3 6.5 0.015 13.9 6.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_phi PF04931.13 CDJ95875.1 - 6.7 4.7 10.7 8.4 4.4 10.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 CDJ95875.1 - 6.9 7.1 15.0 20 5.6 14.6 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain EF-hand_1 PF00036.32 CDJ95876.1 - 6.5e-21 72.3 5.6 2.5e-08 32.9 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CDJ95876.1 - 1.5e-18 67.0 6.7 7.7e-15 55.1 0.5 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ95876.1 - 6.3e-16 56.9 3.8 6.4e-07 28.8 0.1 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 CDJ95876.1 - 3.7e-14 51.5 2.2 1.7e-05 24.1 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CDJ95876.1 - 1.3e-11 44.2 3.6 1.9e-10 40.4 0.4 3.5 3 1 0 3 3 3 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ95876.1 - 6.6e-07 29.6 0.2 5.7e-06 26.6 0.0 2.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CDJ95876.1 - 0.00011 22.1 0.3 0.0013 18.6 0.1 2.5 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 CDJ95876.1 - 0.0012 19.6 0.3 0.023 15.6 0.1 2.4 1 1 2 3 3 3 1 EF-hand domain RHH_1 PF01402.21 CDJ95876.1 - 0.065 13.2 1.3 2.4 8.2 0.0 3.1 2 1 1 3 3 3 0 Ribbon-helix-helix protein, copG family BCNT PF07572.12 CDJ95876.1 - 0.18 11.9 1.0 6.4 6.9 0.0 2.5 2 0 0 2 2 2 0 Bucentaur or craniofacial development Metallophos PF00149.28 CDJ95877.1 - 9.6e-06 26.2 0.0 1.8e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Activin_recp PF01064.23 CDJ95877.1 - 0.075 14.1 2.0 0.16 13.1 2.0 1.6 1 0 0 1 1 1 0 Activin types I and II receptor domain Pkinase PF00069.25 CDJ95880.1 - 2.1e-26 92.8 0.0 2.3e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ95880.1 - 7.8e-09 35.2 0.0 9.6e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ95880.1 - 0.075 12.3 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 CDJ95881.1 - 1.5e-66 224.5 0.0 2e-66 224.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ95881.1 - 8.6e-36 123.5 0.0 1.2e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HTH_48 PF17906.1 CDJ95881.1 - 1e-11 44.8 0.0 2.4e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 HTH domain in Mos1 transposase Kinase-like PF14531.6 CDJ95881.1 - 2.2e-11 43.6 0.0 1.2e-10 41.1 0.0 1.9 1 1 0 2 2 2 1 Kinase-like HTH_32 PF13565.6 CDJ95881.1 - 2.2e-06 28.2 0.2 1.5e-05 25.5 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.6 CDJ95881.1 - 3.5e-05 23.3 0.1 0.00026 20.5 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 CDJ95881.1 - 4.8e-05 23.4 0.0 0.26 11.5 0.0 2.8 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.6 CDJ95881.1 - 0.00012 21.7 0.2 0.13 12.1 0.0 3.1 3 0 0 3 3 2 1 Homeodomain-like domain HTH_Tnp_IS630 PF01710.16 CDJ95881.1 - 0.00013 22.0 0.0 0.00024 21.1 0.0 1.5 1 0 0 1 1 1 1 Transposase HTH_5 PF01022.20 CDJ95881.1 - 0.00029 20.6 0.3 0.0012 18.7 0.1 2.1 2 0 0 2 2 1 1 Bacterial regulatory protein, arsR family HTH_10 PF04967.12 CDJ95881.1 - 0.00031 20.5 0.3 0.0042 16.8 0.0 2.9 4 0 0 4 4 3 1 HTH DNA binding domain IF2_N PF04760.15 CDJ95881.1 - 0.0005 19.8 0.2 0.0016 18.2 0.2 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region HTH_11 PF08279.12 CDJ95881.1 - 0.00061 19.7 0.3 0.0026 17.7 0.0 2.1 2 0 0 2 2 2 1 HTH domain HTH_38 PF13936.6 CDJ95881.1 - 0.0014 18.4 0.0 0.14 12.0 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_50 PF18024.1 CDJ95881.1 - 0.0031 17.1 0.4 0.035 13.7 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain KfrA_N PF11740.8 CDJ95881.1 - 0.0036 18.0 0.0 1.4 9.6 0.0 2.6 1 1 1 2 2 2 1 Plasmid replication region DNA-binding N-term FTA2 PF13095.6 CDJ95881.1 - 0.004 16.8 0.1 1.7 8.2 0.0 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 HTH_29 PF13551.6 CDJ95881.1 - 0.0053 16.7 0.1 1.7 8.8 0.1 2.6 1 1 1 2 2 2 1 Winged helix-turn helix MarR_2 PF12802.7 CDJ95881.1 - 0.0057 16.5 0.0 0.083 12.8 0.0 2.6 2 0 0 2 2 2 1 MarR family HTH_AsnC-type PF13404.6 CDJ95881.1 - 0.018 14.8 0.1 0.17 11.8 0.0 2.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Kdo PF06293.14 CDJ95881.1 - 0.019 14.3 0.3 0.036 13.4 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MarR PF01047.22 CDJ95881.1 - 0.025 14.5 0.0 0.085 12.8 0.0 1.9 1 0 0 1 1 1 0 MarR family HTH_Tnp_Tc3_2 PF01498.18 CDJ95881.1 - 0.028 14.7 0.1 0.18 12.1 0.0 2.4 3 0 0 3 3 2 0 Transposase HTH_20 PF12840.7 CDJ95881.1 - 0.03 14.4 0.1 0.1 12.7 0.0 1.9 2 0 0 2 2 1 0 Helix-turn-helix domain HTH_1 PF00126.27 CDJ95881.1 - 0.032 14.2 0.0 0.087 12.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Fe_dep_repress PF01325.19 CDJ95881.1 - 0.035 14.3 0.1 0.086 13.1 0.1 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_7 PF02796.15 CDJ95881.1 - 0.045 13.8 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Mga PF05043.13 CDJ95881.1 - 0.064 13.8 0.3 3.2 8.4 0.0 2.7 2 0 0 2 2 2 0 Mga helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 CDJ95881.1 - 0.066 13.7 0.8 4.1 8.0 0.1 3.1 2 1 1 3 3 3 0 leucine-zipper of insertion element IS481 TPR_19 PF14559.6 CDJ95881.1 - 0.084 13.4 0.8 0.18 12.3 0.8 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat HTH_AraC PF00165.23 CDJ95881.1 - 0.092 12.9 0.0 0.56 10.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family TrmB PF01978.19 CDJ95881.1 - 0.12 12.3 0.0 0.45 10.4 0.0 2.0 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF4817 PF16087.5 CDJ95881.1 - 0.17 11.7 0.0 0.73 9.7 0.0 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) tRNA-synt_1 PF00133.22 CDJ95882.1 - 1.1e-42 146.1 0.1 2.8e-19 68.8 0.2 4.2 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CDJ95882.1 - 1.2e-26 93.4 0.0 8e-20 70.9 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) BTB PF00651.31 CDJ95882.1 - 5e-17 62.1 0.5 1e-15 57.9 0.1 2.4 2 0 0 2 2 2 1 BTB/POZ domain tRNA-synt_1e PF01406.19 CDJ95882.1 - 1.4e-05 24.6 0.0 0.091 12.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 CDJ95882.1 - 0.1 11.5 0.0 3.4 6.5 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (K) zf-CCHC PF00098.23 CDJ95883.1 - 1.9e-06 27.7 2.5 1.1e-05 25.3 0.9 2.4 2 0 0 2 2 2 1 Zinc knuckle gag-asp_proteas PF13975.6 CDJ95883.1 - 0.0039 17.7 0.0 0.011 16.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Phage_DNA_bind PF02303.17 CDJ95883.1 - 0.067 13.5 0.0 1.3 9.4 0.0 2.4 2 0 0 2 2 2 0 Helix-destabilising protein zf-CCHC_6 PF15288.6 CDJ95883.1 - 0.093 12.6 2.8 0.068 13.0 0.6 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ95883.1 - 0.17 11.6 1.2 0.43 10.3 1.2 1.7 1 0 0 1 1 1 0 Zinc knuckle Collagen PF01391.18 CDJ95884.1 - 4.1e-21 74.5 117.8 3.2e-09 36.4 41.0 4.0 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ95884.1 - 1.3e-20 73.2 0.3 1.6e-20 72.9 0.3 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Ndr PF03096.14 CDJ95885.1 - 2.5e-104 348.0 0.0 2.9e-104 347.7 0.0 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_1 PF00561.20 CDJ95885.1 - 3.4e-05 23.6 0.0 6.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ95885.1 - 0.0094 15.2 0.0 0.014 14.7 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 ORF45 PF17620.2 CDJ95886.1 - 0.13 12.3 0.1 13 5.9 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function Pkinase PF00069.25 CDJ95888.1 - 6e-34 117.6 0.1 6.4e-34 117.5 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ95888.1 - 5.4e-20 71.8 0.0 5.8e-20 71.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ95888.1 - 0.00011 21.7 0.0 0.00011 21.7 0.0 1.0 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CDJ95888.1 - 0.0061 16.5 0.0 0.01 15.7 0.0 1.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDJ95888.1 - 0.043 12.8 0.0 0.043 12.7 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 CDJ95888.1 - 0.051 13.1 0.0 0.065 12.7 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.11 CDJ95888.1 - 0.086 11.9 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Vpu PF00558.19 CDJ95889.1 - 0.0047 16.7 0.2 0.0095 15.7 0.2 1.4 1 0 0 1 1 1 1 Vpu protein Adaptin_binding PF10199.9 CDJ95889.1 - 0.0069 17.0 2.3 0.036 14.7 2.3 2.3 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Ribosomal_L1 PF00687.21 CDJ95890.1 - 3e-45 154.5 3.1 3.5e-45 154.2 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family 7TM_GPCR_Srx PF10328.9 CDJ95892.1 - 2.5e-10 40.4 3.4 2.9e-10 40.2 3.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Ig_3 PF13927.6 CDJ95893.1 - 1.1e-16 61.2 0.0 3.6e-09 37.1 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 CDJ95893.1 - 3.1e-11 43.5 0.0 2.6e-06 27.7 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 CDJ95893.1 - 2.6e-10 40.4 0.0 0.0021 18.2 0.0 3.1 2 1 1 3 3 3 2 Immunoglobulin V-set domain I-set PF07679.16 CDJ95893.1 - 2.9e-10 40.1 0.0 4.2e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 CDJ95893.1 - 5.5e-06 26.5 0.0 0.06 13.5 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 CDJ95893.1 - 0.0001 22.3 0.0 0.0096 16.0 0.0 2.3 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 CDJ95893.1 - 0.00071 19.8 0.0 1 9.6 0.0 2.8 2 1 1 3 3 3 2 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 CDJ95893.1 - 0.0018 18.6 0.1 0.064 13.6 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin C1-set domain BiPBP_C PF06832.12 CDJ95893.1 - 0.14 12.2 0.0 0.45 10.6 0.0 1.8 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family UDPGT PF00201.18 CDJ95894.1 - 1.2e-16 60.6 0.0 1.4e-16 60.4 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 CDJ95895.1 - 1.1e-42 146.5 0.0 1.3e-42 146.2 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ95895.1 - 1.4e-11 44.6 0.0 2.1e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 CDJ95895.1 - 0.00072 18.9 0.0 0.00092 18.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 Glyco_trans_1_4 PF13692.6 CDJ95895.1 - 0.029 14.8 0.0 0.046 14.2 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferases group 1 7TM_GPCR_Srab PF10292.9 CDJ95896.1 - 9.1e-15 54.4 5.6 1.4e-11 44.0 2.2 2.0 1 1 1 2 2 2 2 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Sra PF02117.16 CDJ95896.1 - 1.6e-11 43.6 5.3 2.5e-06 26.6 0.8 2.0 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Sra Moulting_cycle PF04870.16 CDJ95897.1 - 3.1e-145 483.8 22.8 4.4e-107 358.4 10.1 2.5 3 0 0 3 3 3 2 Moulting cycle TFR_dimer PF04253.15 CDJ95897.1 - 0.011 15.9 0.7 0.046 13.8 0.7 2.2 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain Helicase_C_3 PF13625.6 CDJ95897.1 - 0.013 15.7 0.1 2.5 8.2 0.0 2.7 2 0 0 2 2 2 0 Helicase conserved C-terminal domain DUF3437 PF11919.8 CDJ95897.1 - 0.19 11.7 4.7 17 5.4 0.0 4.0 6 0 0 6 6 6 0 Domain of unknown function (DUF3437) DUF4065 PF13274.6 CDJ95897.1 - 9.6 7.1 10.1 13 6.7 0.0 4.0 2 2 1 3 3 3 0 Protein of unknown function (DUF4065) bZIP_2 PF07716.15 CDJ95898.1 - 1.5e-05 25.0 13.0 1.5e-05 25.0 13.0 2.1 1 1 1 2 2 2 1 Basic region leucine zipper SseC PF04888.12 CDJ95898.1 - 0.63 9.6 2.4 0.81 9.2 2.4 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family MCR PF18509.1 CDJ95900.1 - 0.2 11.3 0.3 0.2 11.3 0.3 1.9 2 0 0 2 2 2 0 Magnetochrome domain RIFIN PF02009.16 CDJ95902.1 - 0.0017 18.3 8.7 0.0031 17.5 8.7 1.5 1 0 0 1 1 1 1 Rifin DUF4064 PF13273.6 CDJ95902.1 - 0.0023 18.2 7.1 0.012 15.9 7.1 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4064) DUF4769 PF15992.5 CDJ95902.1 - 0.11 12.3 2.2 0.17 11.7 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) MAP17 PF15807.5 CDJ95902.1 - 0.21 11.9 1.7 0.27 11.4 0.1 2.0 1 1 1 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4834 PF16118.5 CDJ95902.1 - 0.75 10.8 0.1 0.75 10.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Ion_trans_2 PF07885.16 CDJ95903.1 - 9.4e-36 121.6 23.7 1.5e-19 69.7 2.7 2.8 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CDJ95903.1 - 2.4e-06 27.0 13.6 0.00067 19.0 0.1 2.3 2 0 0 2 2 2 2 Ion transport protein BTB_2 PF02214.22 CDJ95906.1 - 1.1e-22 80.2 0.0 1.9e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Y_phosphatase PF00102.27 CDJ95907.1 - 2.1e-20 73.3 0.1 2.5e-20 73.1 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CDJ95907.1 - 0.00044 20.3 0.3 0.00057 19.9 0.3 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CDJ95907.1 - 0.0019 18.0 0.6 0.0025 17.6 0.5 1.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CDJ95907.1 - 0.0068 16.5 0.1 0.013 15.6 0.1 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 CDJ95907.1 - 0.018 14.7 0.2 0.025 14.2 0.2 1.4 1 1 0 1 1 1 0 Tyrosine phosphatase family C2 PF00168.30 CDJ95908.1 - 2.7e-40 136.8 0.1 1.1e-19 70.6 0.0 2.5 3 0 0 3 3 3 2 C2 domain Helicase_C PF00271.31 CDJ95909.1 - 3.4e-25 88.5 0.0 1.9e-24 86.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CDJ95909.1 - 1.7e-12 47.4 0.3 3.4e-12 46.4 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Syja_N PF02383.18 CDJ95910.1 - 8.2e-87 291.5 0.2 1.1e-86 291.1 0.2 1.1 1 0 0 1 1 1 1 SacI homology domain Collagen PF01391.18 CDJ95911.1 - 1.4e-21 76.0 100.7 3.4e-09 36.3 32.5 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ95911.1 - 4.7e-09 36.2 0.5 6.7e-09 35.7 0.5 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Peptidase_C1 PF00112.23 CDJ95913.1 - 5.6e-87 291.4 0.2 7.9e-87 290.9 0.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CDJ95913.1 - 2.7e-10 40.5 0.5 5e-10 39.7 0.5 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CDJ95913.1 - 6.2e-05 21.9 0.2 0.016 14.0 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Retrotrans_gag PF03732.17 CDJ95913.1 - 0.026 14.8 0.1 0.059 13.7 0.1 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein 7tm_1 PF00001.21 CDJ95915.1 - 4e-16 59.1 15.3 4.8e-16 58.9 15.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CDJ95915.1 - 1.7e-06 27.9 13.8 1.7e-06 27.9 13.8 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 CDJ95915.1 - 0.0043 16.8 10.4 0.0094 15.7 10.4 1.7 1 1 0 1 1 1 1 Olfactory receptor DUF2975 PF11188.8 CDJ95915.1 - 0.078 12.9 0.3 0.078 12.9 0.3 3.3 3 2 0 3 3 3 0 Protein of unknown function (DUF2975) RMI2 PF16100.5 CDJ95915.1 - 0.096 12.5 0.1 0.52 10.1 0.2 2.1 2 1 0 2 2 2 0 RecQ-mediated genome instability protein 2 Prok-RING_2 PF14445.6 CDJ95915.1 - 0.62 10.3 3.6 0.77 10.0 0.6 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 2 DUF5373 PF17343.2 CDJ95915.1 - 2.5 7.9 13.5 1.8 8.4 0.2 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5373) DUF2569 PF10754.9 CDJ95915.1 - 3.4 8.1 15.8 1.3 9.4 2.0 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF2569) Reprolysin_5 PF13688.6 CDJ95916.1 - 2.9e-25 89.6 0.0 2.9e-25 89.6 0.0 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 CDJ95916.1 - 9.1e-24 84.4 0.0 1.9e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 CDJ95916.1 - 1.1e-17 64.7 0.0 1.9e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 CDJ95916.1 - 3e-10 40.8 26.2 3e-10 40.8 26.2 3.2 3 0 0 3 3 3 1 Disintegrin Reprolysin_4 PF13583.6 CDJ95916.1 - 2.5e-09 37.1 0.0 4.4e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 CDJ95916.1 - 4.3e-06 27.0 0.0 1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 CDJ95916.1 - 0.00039 20.4 0.0 0.00039 20.4 0.0 2.5 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Peptidase_M43 PF05572.13 CDJ95916.1 - 0.11 12.4 0.2 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A DUF2615 PF11027.8 CDJ95918.1 - 3.5e-32 110.7 0.0 4e-32 110.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) ARS2 PF04959.13 CDJ95920.1 - 5.8 7.2 16.1 9.9 6.5 16.1 1.3 1 0 0 1 1 1 0 Arsenite-resistance protein 2 RabGAP-TBC PF00566.18 CDJ95921.1 - 1.4e-12 47.7 1.1 2.8e-12 46.8 1.1 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.20 CDJ95921.1 - 6.8e-06 26.6 0.0 1.7e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain FAM216B PF15107.6 CDJ95921.1 - 0.0091 15.9 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 1 FAM216B protein family 7tm_1 PF00001.21 CDJ95922.1 - 5e-11 42.4 10.7 7.8e-11 41.8 10.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MARVEL PF01284.23 CDJ95924.1 - 0.017 15.2 13.7 0.023 14.7 13.7 1.3 1 0 0 1 1 1 0 Membrane-associating domain Phage_holin_3_6 PF07332.11 CDJ95924.1 - 0.56 10.3 12.3 0.72 9.9 10.0 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III OppC_N PF12911.7 CDJ95924.1 - 0.69 9.9 8.6 1.5 8.8 2.5 3.2 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C DUF4307 PF14155.6 CDJ95924.1 - 1.9 8.4 4.7 4.2 7.2 0.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4307) APP_E2 PF12925.7 CDJ95925.1 - 6e-65 218.5 20.1 6e-65 218.5 20.1 1.7 2 0 0 2 2 2 1 E2 domain of amyloid precursor protein APP_N PF02177.16 CDJ95925.1 - 1.6e-36 124.6 1.2 1.6e-36 124.6 1.2 2.5 3 0 0 3 3 3 1 Amyloid A4 N-terminal heparin-binding APP_Cu_bd PF12924.7 CDJ95925.1 - 4.9e-21 75.2 3.6 4.9e-21 75.2 3.6 2.0 2 0 0 2 2 2 1 Copper-binding of amyloid precursor, CuBD APP_amyloid PF10515.9 CDJ95925.1 - 1.2e-19 70.5 0.2 5.4e-19 68.4 0.2 2.2 1 0 0 1 1 1 1 Beta-amyloid precursor protein C-terminus PA28_beta PF02252.18 CDJ95925.1 - 0.0035 17.0 2.3 0.0077 15.9 2.3 1.5 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit SSP160 PF06933.11 CDJ95925.1 - 0.017 13.3 1.4 0.032 12.5 1.4 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF4404 PF14357.6 CDJ95925.1 - 0.22 12.2 12.4 7.7 7.2 0.6 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4404) DUF3439 PF11921.8 CDJ95925.1 - 7.9 6.5 8.9 40 4.2 6.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Ribosomal_S6e PF01092.19 CDJ95927.1 - 1.4e-59 199.6 0.2 2.7e-59 198.6 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e UCH PF00443.29 CDJ95928.1 - 8.4e-52 176.2 0.0 1.1e-51 175.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CDJ95928.1 - 3e-16 59.5 12.3 3e-16 59.5 12.3 2.6 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 CDJ95928.1 - 4.3e-14 52.8 0.2 5.2e-11 42.7 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase GCD14 PF08704.10 CDJ95929.1 - 9e-63 212.2 0.0 2.8e-62 210.6 0.0 1.8 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit ESCRT-II PF05871.12 CDJ95929.1 - 1.9e-51 174.0 0.2 2.9e-51 173.4 0.2 1.3 1 0 0 1 1 1 1 ESCRT-II complex subunit Methyltransf_31 PF13847.6 CDJ95929.1 - 0.0071 16.1 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 CDJ95929.1 - 0.013 15.2 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Abp2 PF09441.10 CDJ95929.1 - 0.047 13.8 0.1 0.09 12.8 0.1 1.4 1 0 0 1 1 1 0 ARS binding protein 2 PCMT PF01135.19 CDJ95929.1 - 0.093 12.5 0.0 0.22 11.3 0.0 1.6 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) zf-RING_2 PF13639.6 CDJ95930.1 - 3.2e-12 46.6 9.8 3.2e-12 46.6 9.8 3.2 3 0 0 3 3 2 1 Ring finger domain zf-RING_11 PF17123.5 CDJ95930.1 - 7.3e-08 32.0 6.7 7.3e-08 32.0 6.7 2.8 4 0 0 4 4 4 1 RING-like zinc finger zf-rbx1 PF12678.7 CDJ95930.1 - 7.8e-08 32.5 6.0 7.8e-08 32.5 6.0 2.7 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CDJ95930.1 - 3.4e-07 30.0 8.3 3.4e-07 30.0 8.3 3.2 4 0 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ95930.1 - 9.4e-05 22.3 8.5 9.4e-05 22.3 8.5 3.4 3 1 0 3 3 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CDJ95930.1 - 0.00036 20.3 9.7 0.00036 20.3 9.7 3.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ95930.1 - 0.0056 16.5 7.6 0.0056 16.5 7.6 3.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDJ95930.1 - 0.007 16.4 4.1 0.007 16.4 4.1 2.6 2 1 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PDDEXK_1 PF12705.7 CDJ95930.1 - 0.35 10.8 5.0 0.15 11.9 1.7 2.1 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily T2SSF PF00482.23 CDJ95930.1 - 0.51 10.3 2.5 13 5.7 0.2 2.6 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F zf-HC5HC2H_2 PF13832.6 CDJ95930.1 - 0.58 10.3 15.1 0.35 11.0 4.4 2.7 2 0 0 2 2 2 0 PHD-zinc-finger like domain Prefoldin PF02996.17 CDJ95931.1 - 1.2e-28 99.5 2.4 1.6e-28 99.0 2.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 CDJ95931.1 - 0.012 15.5 2.8 0.21 11.5 0.2 2.3 2 0 0 2 2 2 0 Prefoldin subunit ERM PF00769.19 CDJ95931.1 - 0.013 15.3 1.1 0.024 14.4 1.1 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family HOIP-UBA PF16678.5 CDJ95931.1 - 0.019 15.0 0.6 0.6 10.1 0.1 2.3 2 0 0 2 2 2 0 HOIP UBA domain pair Fib_alpha PF08702.10 CDJ95931.1 - 0.27 11.4 2.3 0.53 10.5 0.7 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Connexin PF00029.19 CDJ95932.1 - 0.036 13.8 0.0 0.044 13.5 0.0 1.1 1 0 0 1 1 1 0 Connexin Motile_Sperm PF00635.26 CDJ95933.1 - 2.9e-07 30.3 0.0 6.2e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain HTH_27 PF13463.6 CDJ95933.1 - 0.077 13.5 0.4 8.5 7.0 0.2 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain DUF3644 PF12358.8 CDJ95933.1 - 0.12 12.9 0.5 0.42 11.1 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3644) DUF2004 PF09406.10 CDJ95933.1 - 0.13 12.6 2.7 8.4 6.8 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2004) SH3_1 PF00018.28 CDJ95935.1 - 3.2e-22 77.9 0.2 1.6e-07 30.8 0.2 3.3 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.6 CDJ95935.1 - 1.2e-18 66.7 0.2 6.3e-05 22.8 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.17 CDJ95935.1 - 5e-16 58.1 0.0 2.5e-05 23.9 0.0 3.2 3 0 0 3 3 3 3 Variant SH3 domain SH3_3 PF08239.11 CDJ95935.1 - 9.2e-10 38.7 0.4 0.0091 16.3 0.0 3.3 3 0 0 3 3 3 3 Bacterial SH3 domain SH3_16 PF18348.1 CDJ95935.1 - 4.6e-08 32.7 0.6 0.00019 21.1 0.1 3.4 3 1 1 4 4 4 2 Bacterial dipeptidyl-peptidase Sh3 domain hSH3 PF14603.6 CDJ95935.1 - 0.00087 19.7 0.0 2.3 8.7 0.0 3.2 3 0 0 3 3 3 1 Helically-extended SH3 domain SH3_10 PF17902.1 CDJ95935.1 - 0.0015 18.6 0.0 0.047 13.8 0.0 2.7 3 0 0 3 3 3 1 SH3 domain SH3_4 PF06347.13 CDJ95935.1 - 0.01 15.6 0.3 13 5.7 0.0 3.3 3 0 0 3 3 3 0 Bacterial SH3 domain Cyclin_N PF00134.23 CDJ95936.1 - 8.1e-06 25.6 0.0 1.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CDJ95936.1 - 1.1e-05 25.5 0.0 3.1e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain CAP PF00188.26 CDJ95938.1 - 2.1e-11 44.7 6.1 2.9e-11 44.3 5.8 1.4 1 1 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CDJ95939.1 - 7.9e-17 62.3 4.4 1.2e-16 61.7 4.4 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family VWA PF00092.28 CDJ95940.1 - 1.2e-35 123.3 13.3 8.8e-21 74.9 5.0 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 CDJ95940.1 - 4.7e-17 62.6 8.9 7.3e-09 36.2 0.3 2.8 4 0 0 4 4 4 2 von Willebrand factor type A domain VWA_3 PF13768.6 CDJ95940.1 - 4.8e-05 23.3 1.0 0.035 14.0 0.1 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain Herpes_U34 PF04541.13 CDJ95940.1 - 0.024 13.9 0.1 0.082 12.2 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus virion protein U34 Vps16_C PF04840.12 CDJ95940.1 - 0.12 11.4 0.1 0.22 10.5 0.1 1.4 1 0 0 1 1 1 0 Vps16, C-terminal region PDCD2_C PF04194.13 CDJ95942.1 - 1.4e-24 87.1 0.5 1.2e-22 80.8 0.1 2.4 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain VMA21 PF09446.10 CDJ95942.1 - 9.7e-15 54.4 4.1 1.7e-14 53.7 4.1 1.4 1 0 0 1 1 1 1 VMA21-like domain zf-MYND PF01753.18 CDJ95942.1 - 1.3e-05 25.2 19.3 1.3e-05 25.2 19.3 3.1 3 0 0 3 3 3 1 MYND finger Cwf_Cwc_15 PF04889.12 CDJ95942.1 - 0.067 12.9 5.7 0.095 12.4 5.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein VMA21 PF09446.10 CDJ95943.1 - 1.5e-17 63.4 6.9 1.5e-17 63.4 6.9 1.4 2 0 0 2 2 2 1 VMA21-like domain RseC_MucC PF04246.12 CDJ95943.1 - 0.072 13.0 0.4 0.13 12.2 0.4 1.4 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Orf78 PF06024.12 CDJ95943.1 - 0.62 10.4 6.8 9.4 6.6 0.0 2.7 2 1 1 3 3 3 0 Orf78 (ac78) ABC2_membrane_3 PF12698.7 CDJ95943.1 - 0.74 8.9 3.6 2 7.4 3.7 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein ORC3_N PF07034.11 CDJ95945.1 - 5.2e-15 55.4 2.1 8.9e-13 48.0 1.9 2.3 2 0 0 2 2 2 2 Origin recognition complex (ORC) subunit 3 N-terminus EKR PF10371.9 CDJ95945.1 - 0.024 14.4 0.0 0.062 13.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF1759 PF03564.15 CDJ95946.1 - 6.1e-20 71.7 0.0 1.5e-19 70.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 CDJ95946.1 - 3.8e-09 36.5 0.0 9.4e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 CDJ95946.1 - 8.2e-05 23.2 0.1 0.0002 21.9 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ95946.1 - 0.00034 21.1 0.0 0.00087 19.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ95946.1 - 0.0062 16.3 0.3 0.012 15.4 0.3 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ95946.1 - 0.054 13.3 0.0 0.17 11.7 0.0 1.8 1 1 0 1 1 1 0 Aspartyl protease Glycos_transf_4 PF00953.21 CDJ95948.1 - 2.2e-34 118.7 12.7 2.2e-34 118.7 12.7 2.0 3 0 0 3 3 3 1 Glycosyl transferase family 4 SR-25 PF10500.9 CDJ95949.1 - 0.65 9.6 59.6 1.7 8.2 19.3 2.7 1 1 2 3 3 3 0 Nuclear RNA-splicing-associated protein PPP5 PF08321.12 CDJ95950.1 - 1.8e-32 111.5 1.0 1.8e-32 111.5 1.0 2.2 3 0 0 3 3 3 1 PPP5 TPR repeat region Metallophos PF00149.28 CDJ95950.1 - 4.2e-32 112.3 0.2 9.8e-32 111.1 0.2 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 CDJ95950.1 - 2.9e-09 36.3 4.9 0.026 14.3 0.2 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ95950.1 - 1.4e-08 34.2 2.6 0.051 13.7 0.2 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ95950.1 - 0.00011 22.2 1.3 0.065 13.5 0.3 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ95950.1 - 0.00021 20.9 4.0 0.29 10.9 0.5 3.6 3 1 1 4 4 4 2 TPR repeat TPR_14 PF13428.6 CDJ95950.1 - 0.00026 21.6 0.8 0.21 12.5 0.4 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ95950.1 - 0.00065 19.8 0.1 0.0013 18.8 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ95950.1 - 0.032 14.7 2.2 0.4 11.2 0.8 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ95950.1 - 0.053 14.2 3.6 0.47 11.2 2.1 2.3 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ95950.1 - 0.083 13.6 1.1 2.9 8.7 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ95950.1 - 0.33 11.3 1.2 6.6 7.1 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat ADH_N PF08240.12 CDJ95951.1 - 6e-23 80.8 1.4 6e-23 80.8 1.4 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDJ95951.1 - 8.9e-22 77.5 0.3 1.6e-21 76.7 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CDJ95951.1 - 0.011 15.1 0.1 0.02 14.3 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain tRNA_U5-meth_tr PF05958.11 CDJ95952.1 - 1.7e-06 27.3 0.0 2.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 CDJ95952.1 - 3.7e-06 26.8 0.0 8.1e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ95952.1 - 9.1e-06 26.3 0.0 2.3e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ95952.1 - 0.00052 19.6 0.1 0.00099 18.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 CDJ95952.1 - 0.00097 19.8 0.9 0.0018 18.9 0.1 2.0 2 1 0 2 2 2 1 Methyltransferase domain RRM_1 PF00076.22 CDJ95952.1 - 0.0053 16.5 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ubie_methyltran PF01209.18 CDJ95952.1 - 0.013 14.9 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 CDJ95952.1 - 0.03 13.9 0.1 0.056 13.0 0.1 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 CDJ95952.1 - 0.049 13.1 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Putative methyltransferase PCNA_N PF00705.18 CDJ95955.1 - 6.3e-46 155.2 5.3 6.3e-46 155.2 5.3 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 CDJ95955.1 - 4.2e-40 136.9 0.1 1e-39 135.6 0.1 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Hus1 PF04005.12 CDJ95955.1 - 1.7e-05 24.1 0.1 3.3e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Hus1-like protein Rad9 PF04139.13 CDJ95955.1 - 0.00086 18.8 1.0 0.0011 18.5 1.0 1.1 1 0 0 1 1 1 1 Rad9 p25-alpha PF05517.12 CDJ95955.1 - 0.0016 18.6 0.0 0.0041 17.3 0.0 1.6 1 0 0 1 1 1 1 p25-alpha ASC PF00858.24 CDJ95956.1 - 9.2e-19 67.7 0.3 9.7e-19 67.6 0.3 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Na_Ala_symp PF01235.17 CDJ95956.1 - 0.071 12.4 0.4 0.084 12.2 0.4 1.1 1 0 0 1 1 1 0 Sodium:alanine symporter family PDEase_I PF00233.19 CDJ95957.1 - 1.1e-63 215.1 6.0 1.6e-63 214.6 6.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PAS PF00989.25 CDJ95957.1 - 3.7e-05 23.7 0.0 0.00013 21.9 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 CDJ95957.1 - 0.01 16.1 0.0 0.032 14.5 0.0 1.9 1 0 0 1 1 1 0 PAS fold PAS_9 PF13426.7 CDJ95957.1 - 0.03 14.6 0.0 0.068 13.4 0.0 1.7 1 0 0 1 1 1 0 PAS domain SSP160 PF06933.11 CDJ95958.1 - 0.15 10.2 9.4 0.22 9.7 9.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Tubulin PF00091.25 CDJ95960.1 - 9.9e-70 234.8 0.0 1.7e-69 234.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDJ95960.1 - 4.3e-42 143.3 0.1 7.5e-42 142.5 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CDJ95960.1 - 2.5e-05 24.5 0.0 5.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CDJ95960.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 CDJ95960.1 - 0.048 12.9 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Tubulin like AAA PF00004.29 CDJ95961.1 - 2.9e-40 137.8 0.0 5.2e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ95961.1 - 1.7e-08 34.1 0.1 4e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CDJ95961.1 - 8.9e-05 22.8 0.1 0.0075 16.5 0.0 2.6 2 1 1 3 3 2 1 AAA domain AAA_16 PF13191.6 CDJ95961.1 - 0.00031 21.2 0.1 0.0045 17.4 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CDJ95961.1 - 0.00038 20.5 0.0 0.0017 18.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 CDJ95961.1 - 0.0044 16.2 0.0 0.0077 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CDJ95961.1 - 0.0052 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CDJ95961.1 - 0.0065 16.6 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CDJ95961.1 - 0.016 15.4 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CDJ95961.1 - 0.017 15.4 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDJ95961.1 - 0.018 14.6 0.0 0.044 13.3 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 CDJ95961.1 - 0.02 14.6 0.1 0.15 11.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CDJ95961.1 - 0.021 15.4 0.0 0.054 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CDJ95961.1 - 0.04 14.3 0.0 0.095 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 CDJ95961.1 - 0.054 12.8 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 KaiC Mg_chelatase PF01078.21 CDJ95961.1 - 0.06 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 CDJ95961.1 - 0.062 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain Sigma54_activ_2 PF14532.6 CDJ95961.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 CDJ95961.1 - 0.096 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CDJ95961.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CDJ95961.1 - 0.12 12.0 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 CDJ95961.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein SOBP PF15279.6 CDJ95962.1 - 6.8 7.2 35.1 9.1 6.8 35.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Aminotran_3 PF00202.21 CDJ95963.1 - 1.1e-33 116.6 0.0 1.3e-33 116.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Peptidase_M13 PF01431.21 CDJ95964.1 - 9.7e-42 142.9 0.0 2.6e-41 141.5 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13_N PF05649.13 CDJ95964.1 - 5.8e-39 134.9 0.0 7.3e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Mtc PF03820.17 CDJ95965.1 - 7e-110 366.9 0.0 7.9e-110 366.8 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Sugar_tr PF00083.24 CDJ95966.1 - 2.6e-55 188.1 13.7 4.2e-55 187.4 13.7 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ95966.1 - 2.1e-22 79.5 17.2 2.1e-22 79.5 17.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 CDJ95966.1 - 0.0016 17.1 1.5 0.0016 17.1 1.5 3.7 2 2 2 4 4 4 2 MFS/sugar transport protein Sugar_tr PF00083.24 CDJ95967.1 - 4.8e-48 164.1 19.3 6.7e-48 163.7 19.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ95967.1 - 8.7e-21 74.2 25.2 8.7e-21 74.2 25.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Utp14 PF04615.13 CDJ95968.1 - 0.14 10.7 38.7 0.15 10.6 38.7 1.0 1 0 0 1 1 1 0 Utp14 protein DUF1773 PF08593.10 CDJ95968.1 - 0.55 11.3 0.1 0.55 11.3 0.1 3.2 1 1 2 3 3 3 0 Domain of unknown function Macoilin PF09726.9 CDJ95968.1 - 0.62 8.6 26.4 0.66 8.5 26.4 1.1 1 0 0 1 1 1 0 Macoilin family Nop14 PF04147.12 CDJ95968.1 - 0.81 7.8 34.0 0.98 7.5 34.0 1.2 1 0 0 1 1 1 0 Nop14-like family Apt1 PF10351.9 CDJ95968.1 - 2.3 7.0 29.8 3.1 6.5 29.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SR-25 PF10500.9 CDJ95969.1 - 0.11 12.1 39.4 0.19 11.3 39.4 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein BUD22 PF09073.10 CDJ95969.1 - 0.22 10.8 32.5 0.25 10.7 32.5 1.0 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.12 CDJ95969.1 - 0.48 9.0 33.5 0.65 8.5 33.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 CDJ95969.1 - 1.2 7.3 28.4 1.4 7.1 28.4 1.0 1 0 0 1 1 1 0 Nop14-like family Trypan_PARP PF05887.11 CDJ95969.1 - 1.8 8.6 8.6 2.3 8.2 8.6 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SDA1 PF05285.12 CDJ95969.1 - 2.4 7.5 30.8 2.9 7.2 30.8 1.0 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 CDJ95969.1 - 3.5 5.8 30.7 3.8 5.7 30.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 CDJ95969.1 - 3.7 6.4 14.5 5 6.0 14.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SURF2 PF05477.11 CDJ95969.1 - 4.4 6.9 24.7 5 6.7 24.7 1.0 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RR_TM4-6 PF06459.12 CDJ95969.1 - 5.7 6.7 21.7 7 6.4 21.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 VIR_N PF15912.5 CDJ95969.1 - 6.5 6.3 15.6 7.4 6.1 15.6 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal PNISR PF15996.5 CDJ95969.1 - 7.8 6.7 24.2 8.9 6.5 24.2 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR CCDC106 PF15794.5 CDJ95969.1 - 8.4 6.0 29.5 16 5.1 29.2 1.5 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 Homeodomain PF00046.29 CDJ95970.1 - 1.7e-22 79.0 7.5 2.2e-22 78.7 7.5 1.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ95970.1 - 0.00023 21.0 0.3 0.00035 20.4 0.3 1.3 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.6 CDJ95970.1 - 0.073 12.9 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Homez PF11569.8 CDJ95970.1 - 0.087 12.3 0.2 0.14 11.6 0.2 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez YdaS_antitoxin PF15943.5 CDJ95970.1 - 0.092 12.6 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF5401 PF17380.2 CDJ95971.1 - 1.9 6.4 5.2 3.2 5.7 5.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Glyco_hydro_1 PF00232.18 CDJ95973.1 - 2.6e-103 345.9 0.2 3.2e-103 345.6 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 7tm_1 PF00001.21 CDJ95974.1 - 5e-34 117.8 18.7 6.4e-34 117.5 18.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDJ95974.1 - 0.0013 18.1 16.4 0.024 13.9 16.4 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw MAP17 PF15807.5 CDJ95975.1 - 0.02 15.1 0.1 0.031 14.5 0.1 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 PAN_1 PF00024.26 CDJ95976.1 - 1.4e-39 133.9 35.7 1.4e-14 53.8 5.4 4.4 4 0 0 4 4 4 4 PAN domain PAN_3 PF08277.12 CDJ95976.1 - 0.0049 16.7 0.2 0.0049 16.7 0.2 5.0 5 1 0 5 5 5 2 PAN-like domain Phosphorylase PF00343.20 CDJ95978.1 - 1e-47 162.9 0.6 1.4e-47 162.4 0.1 1.4 2 0 0 2 2 2 1 Carbohydrate phosphorylase Ribonuclease_T2 PF00445.18 CDJ95980.1 - 2e-45 155.2 0.0 2.6e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family WH1 PF00568.23 CDJ95981.1 - 2.1e-22 79.1 0.3 3.7e-22 78.4 0.3 1.4 1 0 0 1 1 1 1 WH1 domain VASP_tetra PF08776.11 CDJ95981.1 - 4.4e-13 48.6 2.2 8.3e-13 47.7 2.2 1.4 1 0 0 1 1 1 1 VASP tetramerisation domain DCP1 PF06058.13 CDJ95981.1 - 0.031 14.2 0.1 0.053 13.4 0.1 1.4 1 0 0 1 1 1 0 Dcp1-like decapping family PPP4R2 PF09184.11 CDJ95982.1 - 4.7e-16 59.2 0.7 6.1e-16 58.9 0.7 1.4 1 1 0 1 1 1 1 PPP4R2 AAA_23 PF13476.6 CDJ95982.1 - 0.039 14.5 0.1 0.044 14.3 0.1 1.1 1 0 0 1 1 1 0 AAA domain SAND PF01342.21 CDJ95983.1 - 1.9e-17 62.7 0.9 5.4e-17 61.3 0.2 2.1 2 0 0 2 2 2 1 SAND domain CutA1 PF03091.15 CDJ95984.1 - 4.7e-34 116.2 0.7 8.6e-34 115.4 0.7 1.4 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein 7tm_1 PF00001.21 CDJ95984.1 - 7.3e-27 94.3 21.7 1.2e-26 93.6 21.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Srg PF02118.21 CDJ95984.1 - 0.012 15.3 15.1 0.021 14.5 15.1 1.5 1 0 0 1 1 1 0 Srg family chemoreceptor T7SS_ESX_EspC PF10824.8 CDJ95986.1 - 0.21 12.1 0.0 2.6 8.6 0.0 2.2 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm 7TM_GPCR_Srv PF10323.9 CDJ95987.1 - 1.1e-17 64.3 14.6 1.4e-17 63.9 14.6 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 CDJ95987.1 - 3e-09 36.9 14.7 7.9e-09 35.5 14.6 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 CDJ95987.1 - 1.6e-08 34.2 10.1 1.6e-08 34.2 10.1 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Srg PF02118.21 CDJ95987.1 - 1.2e-06 28.4 18.3 1.6e-06 28.0 18.3 1.3 1 1 0 1 1 1 1 Srg family chemoreceptor Mucin PF01456.17 CDJ95988.1 - 0.25 11.3 17.4 0.31 11.0 17.4 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein 7TM_GPCR_Srw PF10324.9 CDJ95989.1 - 2e-08 33.9 4.5 2.6e-08 33.5 4.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF3671 PF12420.8 CDJ95989.1 - 9.4 6.4 6.6 5.7 7.1 4.7 1.5 1 1 1 2 2 2 0 Protein of unknown function RE_HaeIII PF09556.10 CDJ95990.1 - 0.074 12.1 0.2 0.13 11.3 0.0 1.4 2 0 0 2 2 2 0 HaeIII restriction endonuclease Seryl_tRNA_N PF02403.22 CDJ95990.1 - 0.1 12.8 2.4 5.9 7.2 0.2 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CppA_N PF14506.6 CDJ95990.1 - 0.16 12.1 0.6 0.45 10.6 0.3 1.7 2 0 0 2 2 2 0 CppA N-terminal VSG_B PF13206.6 CDJ95990.1 - 7.2 5.8 7.5 5.9 6.0 2.8 2.0 1 1 1 2 2 2 0 Trypanosomal VSG domain Cmc1 PF08583.10 CDJ95991.1 - 0.0047 16.9 5.7 0.0063 16.5 2.6 2.2 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 CDJ95991.1 - 0.0078 16.3 3.0 0.0078 16.3 3.0 1.8 2 0 0 2 2 2 1 CHCH domain CX9C PF16860.5 CDJ95991.1 - 2.6 8.1 8.9 5.3 7.1 6.0 2.7 2 1 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, WD40 PF00400.32 CDJ95992.1 - 0.00067 20.4 4.4 0.0085 16.9 0.0 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat WD40 PF00400.32 CDJ95993.1 - 2.4e-05 25.0 0.0 0.047 14.6 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ95993.1 - 0.0074 16.6 0.0 0.72 10.2 0.0 3.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Prefoldin PF02996.17 CDJ95994.1 - 8.9e-25 86.9 6.3 2.1e-23 82.5 1.5 2.6 3 0 0 3 3 3 2 Prefoldin subunit RNase_PH PF01138.21 CDJ95994.1 - 3.7e-22 79.2 0.2 1.4e-21 77.3 0.0 2.1 3 0 0 3 3 3 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CDJ95994.1 - 3.4e-09 36.6 0.0 7.1e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Nsp1_C PF05064.13 CDJ95994.1 - 0.044 13.6 2.9 0.045 13.6 0.2 2.3 3 0 0 3 3 3 0 Nsp1-like C-terminal region Zein-binding PF04576.15 CDJ95994.1 - 9.7 6.6 8.3 2 8.8 0.2 2.8 3 0 0 3 3 3 0 Zein-binding OST-HTH PF12872.7 CDJ95995.1 - 3.2e-05 23.6 0.0 0.0017 18.1 0.0 2.8 3 0 0 3 3 3 2 OST-HTH/LOTUS domain Astacin PF01400.24 CDJ95996.1 - 1.3e-71 240.2 0.0 1.7e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB PF00431.20 CDJ95996.1 - 2.6e-06 27.7 0.0 6.2e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 CUB domain Peptidase_M10 PF00413.24 CDJ95996.1 - 0.00083 19.2 0.0 0.46 10.3 0.0 2.5 2 0 0 2 2 2 2 Matrixin FAM101 PF15068.6 CDJ95996.1 - 0.017 15.1 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 FAM101 family Peptidase_M8 PF01457.16 CDJ95996.1 - 0.063 12.0 0.0 0.097 11.3 0.0 1.2 1 0 0 1 1 1 0 Leishmanolysin DUF3810 PF12725.7 CDJ95996.1 - 0.21 10.9 1.4 0.64 9.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) EGF_2 PF07974.13 CDJ95996.1 - 2.6 8.5 12.5 6.4 7.2 12.5 1.7 1 0 0 1 1 1 0 EGF-like domain Neur_chan_LBD PF02931.23 CDJ95997.1 - 2.9e-35 121.7 2.6 4.3e-35 121.1 2.6 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ95997.1 - 1.2e-26 94.3 0.4 2.7e-26 93.1 0.4 1.6 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region F-box-like PF12937.7 CDJ95998.1 - 7.2e-09 35.4 1.0 7.2e-09 35.4 1.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CDJ95998.1 - 2.3e-07 30.5 1.7 2.3e-07 30.5 1.7 2.0 2 0 0 2 2 2 1 F-box domain LysR_substrate PF03466.20 CDJ95998.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 LysR substrate binding domain 7tm_1 PF00001.21 CDJ95999.1 - 1.5e-14 54.0 1.2 1.8e-14 53.7 1.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ95999.1 - 0.0031 16.9 0.1 0.0042 16.5 0.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 CDJ95999.1 - 0.0034 17.2 1.0 0.0041 16.9 1.0 1.1 1 0 0 1 1 1 1 Olfactory receptor SUIM_assoc PF16619.5 CDJ95999.1 - 0.014 15.4 1.0 2.2 8.4 0.5 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF2181 PF10223.9 CDJ96000.1 - 2.3e-57 194.3 0.1 3.4e-57 193.7 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2181) Cullin PF00888.22 CDJ96001.1 - 6.7e-167 556.8 3.0 9e-167 556.4 3.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CDJ96001.1 - 8.5e-18 64.2 2.1 2.6e-17 62.6 2.1 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain adh_short PF00106.25 CDJ96002.1 - 1.6e-34 119.1 0.0 2.1e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ96002.1 - 2.7e-21 76.2 0.0 4.5e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ96002.1 - 0.0035 17.3 0.0 0.0068 16.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Baculo_helicase PF04735.12 CDJ96002.1 - 0.018 12.6 0.2 0.025 12.2 0.2 1.1 1 0 0 1 1 1 0 Baculovirus DNA helicase SIX1_SD PF16878.5 CDJ96005.1 - 5.2e-38 130.0 1.0 5.2e-38 130.0 1.0 1.9 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 CDJ96005.1 - 7.7e-14 51.3 2.1 7.7e-14 51.3 2.1 2.0 2 1 1 3 3 3 1 Homeodomain Homeobox_KN PF05920.11 CDJ96005.1 - 3.2e-11 42.9 1.8 6.7e-11 41.9 0.3 2.4 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.8 CDJ96005.1 - 0.022 14.2 0.1 0.049 13.1 0.1 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez ANAPC3 PF12895.7 CDJ96005.1 - 0.034 14.4 0.7 0.12 12.6 0.4 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 YdaS_antitoxin PF15943.5 CDJ96005.1 - 0.15 12.0 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT PID PF00640.23 CDJ96006.1 - 5.5e-30 104.2 0.0 2.5e-27 95.6 0.0 2.1 2 0 0 2 2 2 2 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 CDJ96006.1 - 8.6e-05 22.7 0.0 0.0003 20.9 0.0 1.9 1 1 0 1 1 1 1 Phosphotyrosine-binding domain Collagen PF01391.18 CDJ96007.1 - 2.1e-17 62.6 121.7 0.0042 16.8 17.2 4.1 2 2 0 2 2 2 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ96007.1 - 3e-09 36.8 1.1 4.1e-09 36.3 1.1 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ96009.1 - 1.1e-15 57.1 93.0 3.2e-07 30.0 37.4 3.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ96009.1 - 0.12 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Tmem26 PF09772.9 CDJ96010.1 - 8.1e-83 278.1 12.9 6e-82 275.2 12.9 1.9 1 1 0 1 1 1 1 Transmembrane protein 26 Ribosomal_S27e PF01667.17 CDJ96011.1 - 1.3e-27 95.2 7.2 1.6e-27 95.0 7.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 OSCP PF00213.18 CDJ96012.1 - 5.7e-48 163.3 2.7 6.6e-48 163.1 2.7 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit COG5 PF10392.9 CDJ96012.1 - 0.0046 17.1 2.3 1.9 8.7 0.1 2.5 3 0 0 3 3 3 2 Golgi transport complex subunit 5 Dynactin PF12455.8 CDJ96012.1 - 0.022 14.0 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Dynein associated protein RNA_pol_Rpb6 PF01192.22 CDJ96013.1 - 4.3e-13 48.9 0.1 6.6e-13 48.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Utp14 PF04615.13 CDJ96014.1 - 1.2e-106 358.2 73.6 1.3e-106 358.0 73.6 1.0 1 0 0 1 1 1 1 Utp14 protein Proteasome PF00227.26 CDJ96015.1 - 1.4e-43 148.6 0.9 2.1e-43 148.1 0.9 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ96015.1 - 4.9e-14 51.7 0.1 1.2e-13 50.4 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF5018 PF16410.5 CDJ96015.1 - 0.0056 15.4 0.3 0.015 14.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5018) DUF2218 PF09981.9 CDJ96015.1 - 0.13 12.6 0.3 0.29 11.6 0.3 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2218) TFIIS_C PF01096.18 CDJ96016.1 - 1.6e-17 63.1 8.4 2.8e-17 62.3 2.7 2.4 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) DZR PF12773.7 CDJ96016.1 - 3.4e-05 23.8 5.7 0.016 15.3 0.5 2.4 2 0 0 2 2 2 2 Double zinc ribbon TF_Zn_Ribbon PF08271.12 CDJ96016.1 - 0.013 15.0 10.3 7 6.3 0.0 4.4 3 1 1 4 4 4 0 TFIIB zinc-binding PHD PF00628.29 CDJ96016.1 - 0.026 14.4 6.8 2 8.4 2.0 2.5 2 1 0 2 2 2 0 PHD-finger A2L_zn_ribbon PF08792.10 CDJ96016.1 - 0.026 14.3 15.5 0.87 9.4 0.2 4.2 4 1 0 4 4 4 0 A2L zinc ribbon domain Baculo_LEF5_C PF11792.8 CDJ96016.1 - 0.031 14.0 6.1 0.34 10.6 0.1 2.9 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain Rpr2 PF04032.16 CDJ96016.1 - 0.034 14.4 9.7 0.034 14.4 2.1 2.9 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain OrfB_Zn_ribbon PF07282.11 CDJ96016.1 - 0.074 13.0 7.6 0.35 10.8 0.2 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 CDJ96016.1 - 0.08 12.4 10.3 2.3 7.8 0.3 3.6 4 0 0 4 4 4 0 zinc-ribbon domain UPF0547 PF10571.9 CDJ96016.1 - 0.087 12.9 8.8 1.1 9.4 0.1 3.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-C2H2_3 PF13878.6 CDJ96016.1 - 0.11 12.4 2.0 11 5.9 0.0 3.2 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO DUF678 PF05077.12 CDJ96016.1 - 0.11 12.6 4.7 0.53 10.5 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF678) zf-RRPl_C4 PF17026.5 CDJ96016.1 - 0.31 11.1 6.6 1 9.5 6.8 1.7 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-HIT PF04438.16 CDJ96016.1 - 0.54 10.2 16.0 14 5.6 0.1 4.4 5 0 0 5 5 4 0 HIT zinc finger zinc_ribbon_2 PF13240.6 CDJ96016.1 - 0.68 9.7 12.3 3.2 7.6 0.2 3.7 4 0 0 4 4 4 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 CDJ96016.1 - 0.71 10.0 10.5 1.1 9.5 0.7 3.1 2 1 0 2 2 2 0 Zinc ribbon domain zf_UBZ PF18439.1 CDJ96016.1 - 0.72 9.5 9.8 17 5.1 0.1 4.0 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger RNA_POL_M_15KD PF02150.16 CDJ96016.1 - 0.82 9.6 7.0 3.6 7.5 0.2 3.2 2 1 1 3 3 3 0 RNA polymerases M/15 Kd subunit RNHCP PF12647.7 CDJ96016.1 - 0.83 9.7 8.1 1.9 8.5 3.7 2.6 1 1 1 2 2 2 0 RNHCP domain DNA_RNApol_7kD PF03604.13 CDJ96016.1 - 0.98 9.1 8.8 1.6 8.5 0.3 3.2 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-NADH-PPase PF09297.11 CDJ96016.1 - 1.9 8.2 7.9 3.1 7.5 0.2 3.1 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 CDJ96016.1 - 3.5 7.7 9.7 0.29 11.1 1.0 2.6 2 1 1 3 3 3 0 Transposase zinc-ribbon domain ProRS-C_1 PF09180.11 CDJ96017.1 - 1.6e-20 73.0 0.4 4.4e-20 71.7 0.4 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 CDJ96017.1 - 1.3e-18 66.9 0.0 2.8e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CDJ96017.1 - 1.7e-16 60.7 0.0 3.6e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 CDJ96017.1 - 1.3e-14 54.1 1.9 5.1e-14 52.2 1.9 2.1 1 0 0 1 1 1 1 WHEP-TRS domain TPR_14 PF13428.6 CDJ96018.1 - 9.9e-16 57.1 30.9 0.18 12.7 2.3 11.6 9 3 5 14 14 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ96018.1 - 1.5e-15 57.4 22.9 0.0022 18.4 1.6 8.6 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ96018.1 - 4.7e-15 54.7 18.0 0.0069 16.2 0.0 8.8 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ96018.1 - 2.8e-14 52.5 10.0 0.03 14.0 0.3 8.1 7 1 1 8 8 8 4 TPR repeat TPR_2 PF07719.17 CDJ96018.1 - 4.4e-14 51.4 31.8 0.023 14.8 0.0 11.6 14 0 0 14 14 14 5 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ96018.1 - 1.9e-13 49.4 8.3 0.0047 17.0 0.8 8.2 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ96018.1 - 2.3e-12 46.4 14.5 0.19 12.2 0.2 8.6 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ96018.1 - 3.1e-07 30.6 8.4 4.1 8.3 0.0 7.5 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ96018.1 - 3.9e-07 30.3 14.2 0.36 11.2 0.3 7.5 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ96018.1 - 2.2e-06 28.2 29.3 0.046 14.4 0.0 8.8 7 2 2 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ96018.1 - 4.3e-05 23.2 5.6 2 8.6 0.0 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ96018.1 - 0.00096 18.9 15.2 1.5 8.8 0.1 7.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ96018.1 - 0.0025 17.9 4.2 0.26 11.5 0.1 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat APOBEC1 PF18769.1 CDJ96018.1 - 0.067 13.5 0.7 0.24 11.7 0.7 1.9 1 0 0 1 1 1 0 APOBEC1 DUF4919 PF16266.5 CDJ96018.1 - 0.16 11.9 0.1 3.8 7.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) Leuk-A4-hydro_C PF09127.11 CDJ96018.1 - 0.31 11.1 5.2 0.42 10.7 0.1 3.9 6 0 0 6 6 5 0 Leukotriene A4 hydrolase, C-terminal ANAPC5 PF12862.7 CDJ96018.1 - 3 8.0 6.6 9.8 6.3 0.3 3.7 4 0 0 4 4 3 0 Anaphase-promoting complex subunit 5 SNAD4 PF18750.1 CDJ96018.1 - 8.3 6.6 8.3 0.81 9.8 2.7 2.2 3 0 0 3 3 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 BTAD PF03704.17 CDJ96018.1 - 8.6 6.8 9.0 4.3 7.8 0.0 3.9 3 2 2 5 5 5 0 Bacterial transcriptional activator domain NDUF_B4 PF07225.12 CDJ96019.1 - 3.9e-34 117.2 0.2 6.3e-34 116.5 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) DUF3951 PF13131.6 CDJ96020.1 - 0.13 12.5 4.2 0.34 11.1 4.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) MARVEL PF01284.23 CDJ96021.1 - 0.016 15.3 9.4 0.021 14.9 9.4 1.1 1 0 0 1 1 1 0 Membrane-associating domain Transpos_assoc PF13963.6 CDJ96021.1 - 0.016 15.5 0.2 0.027 14.8 0.2 1.3 1 0 0 1 1 1 0 Transposase-associated domain HTH_50 PF18024.1 CDJ96021.1 - 0.029 14.0 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain YfhO PF09586.10 CDJ96021.1 - 0.79 7.9 5.3 0.92 7.7 5.3 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF3810 PF12725.7 CDJ96021.1 - 1 8.7 3.7 1.4 8.2 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Amastin PF07344.11 CDJ96021.1 - 2.7 7.8 16.7 1.7 8.5 13.4 2.1 1 1 1 2 2 2 0 Amastin surface glycoprotein Wzy_C PF04932.15 CDJ96022.1 - 0.0042 16.7 0.3 0.0048 16.5 0.3 1.2 1 0 0 1 1 1 1 O-Antigen ligase Otopetrin PF03189.13 CDJ96022.1 - 0.033 13.0 0.5 0.045 12.6 0.5 1.2 1 0 0 1 1 1 0 Otopetrin DUF4220 PF13968.6 CDJ96022.1 - 0.035 13.5 0.0 0.042 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) TMEM100 PF16311.5 CDJ96022.1 - 0.095 12.3 0.8 0.15 11.7 0.8 1.4 1 0 0 1 1 1 0 Transmembrane protein 100 Pox_P21 PF05313.12 CDJ96022.1 - 0.11 12.1 6.7 0.16 11.5 6.7 1.2 1 0 0 1 1 1 0 Poxvirus P21 membrane protein G3P_acyltransf PF02660.15 CDJ96022.1 - 1.4 9.0 11.4 1.9 8.6 11.4 1.1 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase WTF PF03303.13 CDJ96023.1 - 0.0033 17.2 7.2 0.0092 15.7 7.2 1.7 1 1 0 1 1 1 1 WTF protein Ndc1_Nup PF09531.10 CDJ96023.1 - 0.028 13.1 1.3 0.035 12.8 1.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SpecificRecomb PF10136.9 CDJ96023.1 - 0.73 8.1 8.9 0.81 7.9 8.9 1.1 1 0 0 1 1 1 0 Site-specific recombinase DUF5373 PF17343.2 CDJ96023.1 - 0.77 9.6 19.9 0.99 9.2 19.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5373) Peptidase_U4 PF03419.13 CDJ96023.1 - 1.6 8.0 15.4 1.9 7.7 15.4 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Trypsin PF00089.26 CDJ96024.1 - 1e-17 64.7 0.3 9.2e-17 61.6 0.3 2.4 1 1 0 1 1 1 1 Trypsin DUF316 PF03761.15 CDJ96024.1 - 7.6e-12 45.4 1.6 3.1e-09 36.8 0.5 2.3 2 0 0 2 2 2 2 Chymotrypsin family Peptidase-S1 DUF1986 PF09342.11 CDJ96024.1 - 0.016 15.6 0.1 0.041 14.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1986) Trypsin PF00089.26 CDJ96025.1 - 2.7e-15 56.8 0.0 1.5e-14 54.3 0.0 2.0 1 1 0 1 1 1 1 Trypsin DUF316 PF03761.15 CDJ96025.1 - 6.9e-10 39.0 0.6 1e-08 35.1 0.3 2.3 2 0 0 2 2 2 1 Chymotrypsin family Peptidase-S1 Transposase_1 PF01359.18 CDJ96025.1 - 0.0005 19.8 0.1 0.0014 18.4 0.0 1.7 2 0 0 2 2 2 1 Transposase (partial DDE domain) DUF1986 PF09342.11 CDJ96025.1 - 0.033 14.6 0.0 0.091 13.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Tachylectin PF14517.6 CDJ96025.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Tachylectin Neur_chan_LBD PF02931.23 CDJ96026.1 - 3.9e-59 199.7 1.6 5.6e-59 199.2 1.6 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ96026.1 - 3.2e-31 109.2 2.0 3.2e-31 109.2 2.0 2.4 2 1 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Vac_Fusion PF02346.16 CDJ96028.1 - 0.012 15.2 0.9 1.1 8.9 0.0 2.6 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 RVT_1 PF00078.27 CDJ96029.1 - 3e-20 72.7 0.0 4.4e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pyr_redox_2 PF07992.14 CDJ96030.1 - 2.4e-56 191.1 0.1 3.2e-56 190.7 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDJ96030.1 - 8.6e-24 83.9 1.6 3.8e-18 65.8 0.2 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CDJ96030.1 - 6.3e-17 61.8 0.2 1.9e-15 56.9 0.0 1.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 CDJ96030.1 - 4.2e-16 58.7 0.0 9.7e-16 57.5 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain K_oxygenase PF13434.6 CDJ96030.1 - 0.00053 19.2 0.0 0.37 9.9 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Reductase_C PF14759.6 CDJ96030.1 - 0.0012 19.4 0.0 0.0037 17.8 0.0 1.9 1 0 0 1 1 1 1 Reductase C-terminal NAD_binding_7 PF13241.6 CDJ96030.1 - 0.003 18.0 0.4 0.18 12.3 0.2 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.6 CDJ96030.1 - 0.061 13.3 0.4 9.3 6.2 0.1 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.14 CDJ96030.1 - 0.1 11.3 0.0 2.3 6.8 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 CDJ96030.1 - 0.19 10.8 0.2 1.3 8.0 0.0 2.1 1 1 1 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.24 CDJ96030.1 - 0.23 10.7 0.2 0.97 8.6 0.1 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase TIMP PF00965.17 CDJ96031.1 - 3.8e-11 43.1 0.6 7.4e-10 38.9 0.6 2.0 1 1 0 1 1 1 1 Tissue inhibitor of metalloproteinase ASH PF15780.5 CDJ96032.1 - 7.6e-06 26.1 0.0 3.1e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin CARDB PF07705.11 CDJ96032.1 - 0.039 14.2 1.7 0.14 12.4 0.0 2.7 3 0 0 3 3 3 0 CARDB 7tm_1 PF00001.21 CDJ96033.1 - 8.5e-07 28.6 10.3 2e-06 27.3 9.5 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Sigma_reg_N PF13800.6 CDJ96033.1 - 0.69 10.2 0.0 0.69 10.2 0.0 3.1 2 1 1 3 3 3 0 Sigma factor regulator N-terminal MatE PF01554.18 CDJ96033.1 - 3.4 7.3 12.3 0.36 10.5 6.6 2.2 3 0 0 3 3 3 0 MatE Shisa PF13908.6 CDJ96033.1 - 8.5 6.6 7.3 0.49 10.6 0.3 2.3 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF996 PF06195.13 CDJ96033.1 - 9.2 6.6 10.8 3 8.1 4.7 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF996) DUF1272 PF06906.11 CDJ96034.1 - 3.6 7.7 7.6 7 6.8 3.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) HAUS5 PF14817.6 CDJ96036.1 - 0.012 14.4 1.5 0.012 14.4 0.8 1.3 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 5 DUF3499 PF12005.8 CDJ96036.1 - 0.049 14.2 1.2 1.1 9.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) HBS1_N PF08938.10 CDJ96036.1 - 1.1 9.6 7.1 2 8.8 1.8 2.5 2 1 0 2 2 2 0 HBS1 N-terminus Sulfate_transp PF00916.20 CDJ96037.1 - 3.6e-106 355.1 22.8 4.9e-106 354.7 22.8 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CDJ96037.1 - 4.9e-26 90.7 0.0 8.8e-26 89.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain TMEMspv1-c74-12 PF11044.8 CDJ96037.1 - 0.047 13.7 1.0 0.14 12.1 1.0 1.8 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein MFS_MOT1 PF16983.5 CDJ96037.1 - 0.31 11.5 8.6 0.1 13.0 3.3 2.7 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily PAP2 PF01569.21 CDJ96037.1 - 5.5 6.8 18.2 1.2 8.9 4.1 3.6 2 1 1 3 3 3 0 PAP2 superfamily Collagen PF01391.18 CDJ96038.1 - 7.3e-27 92.9 89.9 1.5e-09 37.5 32.7 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ96038.1 - 1.4e-13 50.7 0.9 1.8e-13 50.3 0.9 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain EamA PF00892.20 CDJ96039.1 - 0.0012 19.1 8.8 0.023 14.9 6.2 2.0 2 0 0 2 2 2 2 EamA-like transporter family Ribosomal_S18 PF01084.20 CDJ96040.1 - 2.1e-14 53.5 0.0 3.8e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 LRR_4 PF12799.7 CDJ96040.1 - 5.9e-12 45.6 11.7 0.0017 18.7 0.0 5.5 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ96040.1 - 3.2e-10 39.6 18.0 5.5e-05 22.8 0.6 5.2 4 1 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 CDJ96040.1 - 0.0013 19.0 12.6 17 6.5 0.1 7.4 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.6 CDJ96040.1 - 0.011 15.7 11.5 28 5.1 0.1 6.5 6 0 0 6 6 6 0 Leucine Rich repeat LRR_9 PF14580.6 CDJ96040.1 - 0.019 14.5 1.6 0.21 11.1 0.4 2.6 1 1 1 2 2 2 0 Leucine-rich repeat WD40 PF00400.32 CDJ96041.1 - 1.6e-30 104.7 20.0 9e-09 35.8 0.5 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ96041.1 - 4.1e-06 27.0 0.9 3.1 8.2 0.0 4.3 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDJ96041.1 - 6.1e-05 21.9 3.1 0.23 10.1 0.0 3.2 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CDJ96041.1 - 0.0042 15.9 0.3 2.7 6.6 0.3 2.5 2 1 0 2 2 2 2 Nup133 N terminal like WD40_like PF17005.5 CDJ96041.1 - 0.093 12.0 0.0 0.33 10.2 0.0 1.9 2 0 0 2 2 2 0 WD40-like domain Frtz PF11768.8 CDJ96041.1 - 0.21 9.9 0.0 5 5.3 0.0 2.0 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz RVT_1 PF00078.27 CDJ96042.1 - 2.6e-22 79.4 0.0 4.2e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDJ96042.1 - 0.00017 21.4 0.0 0.00043 20.1 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Lectin_C PF00059.21 CDJ96043.1 - 0.0012 19.6 1.5 0.0014 19.4 1.5 1.2 1 0 0 1 1 1 1 Lectin C-type domain Neur_chan_LBD PF02931.23 CDJ96045.1 - 7.5e-23 81.1 0.1 8.7e-23 80.9 0.1 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.23 CDJ96046.1 - 2.2e-30 105.7 0.7 2.4e-30 105.6 0.7 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain COesterase PF00135.28 CDJ96047.1 - 9.4e-38 130.3 0.0 1.1e-37 130.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family CAAX_1 PF15895.5 CDJ96047.1 - 0.12 12.3 0.3 5.7 6.8 0.1 2.1 1 1 1 2 2 2 0 CAAX box cerebral protein 1 COesterase PF00135.28 CDJ96048.1 - 1.3e-47 162.9 0.0 1.5e-47 162.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDJ96048.1 - 0.00016 21.6 0.0 0.00019 21.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold IMP_cyclohyd PF07826.11 CDJ96048.1 - 0.074 12.6 0.0 0.086 12.4 0.0 1.1 1 0 0 1 1 1 0 IMP cyclohydrolase-like protein HTH_48 PF17906.1 CDJ96050.1 - 1.7e-18 66.4 0.7 2.9e-18 65.7 0.7 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_23 PF13384.6 CDJ96050.1 - 9.7e-07 28.4 0.0 0.0057 16.4 0.0 2.4 2 0 0 2 2 2 2 Homeodomain-like domain HTH_38 PF13936.6 CDJ96050.1 - 1.6e-05 24.5 0.0 3.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 CDJ96050.1 - 7.4e-05 22.8 0.0 0.59 10.3 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 CDJ96050.1 - 0.00025 21.2 0.3 0.00089 19.5 0.2 1.8 2 0 0 2 2 2 1 Transposase HTH_Tnp_IS630 PF01710.16 CDJ96050.1 - 0.00026 21.0 0.0 0.00032 20.7 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 CDJ96050.1 - 0.00097 19.7 0.0 0.0015 19.1 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 CDJ96050.1 - 0.0016 18.4 0.0 0.67 10.0 0.0 2.2 2 0 0 2 2 2 2 Winged helix-turn helix HTH_50 PF18024.1 CDJ96050.1 - 0.0018 17.8 0.0 0.0046 16.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 CDJ96050.1 - 0.0028 17.9 0.2 2 8.8 0.0 2.2 1 1 1 2 2 2 2 Transposase HTH_Tnp_ISL3 PF13542.6 CDJ96050.1 - 0.052 13.0 0.1 0.4 10.1 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_10 PF04967.12 CDJ96050.1 - 0.093 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain Aldose_epim PF01263.20 CDJ96051.1 - 8e-58 196.1 0.0 9e-58 195.9 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase F-box PF00646.33 CDJ96052.1 - 2.7e-05 23.9 0.0 5.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 F-box domain Clathrin_lg_ch PF01086.17 CDJ96053.1 - 7.3e-38 130.9 1.7 1.2e-37 130.1 1.7 1.3 1 1 0 1 1 1 1 Clathrin light chain ImpA_N PF06812.12 CDJ96053.1 - 0.098 12.8 2.9 0.14 12.3 0.5 2.0 1 1 1 2 2 2 0 ImpA, N-terminal, type VI secretion system SlyX PF04102.12 CDJ96054.1 - 0.001 19.7 0.9 0.001 19.7 0.9 5.8 2 2 4 6 6 6 2 SlyX Fez1 PF06818.15 CDJ96054.1 - 0.0032 18.0 11.3 0.0032 18.0 11.3 3.0 1 1 2 3 3 3 1 Fez1 TMEM192 PF14802.6 CDJ96054.1 - 0.63 9.1 5.6 2.7 7.0 0.5 2.7 3 0 0 3 3 3 0 TMEM192 family DUF695 PF05117.12 CDJ96054.1 - 0.78 9.9 0.1 0.78 9.9 0.1 2.7 4 0 0 4 4 4 0 Family of unknown function (DUF695) RIO1 PF01163.22 CDJ96054.1 - 1.2 8.7 6.3 0.27 10.8 2.1 2.1 2 1 0 2 2 2 0 RIO1 family NPV_P10 PF05531.12 CDJ96054.1 - 1.6 9.3 15.5 0.21 12.1 0.7 4.3 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein WHEP-TRS PF00458.20 CDJ96054.1 - 2.8 8.1 9.9 17 5.7 0.3 3.5 3 1 0 3 3 3 0 WHEP-TRS domain DUF745 PF05335.13 CDJ96054.1 - 5.9 6.6 27.6 1.4 8.6 1.6 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF745) Allexi_40kDa PF05549.11 CDJ96054.1 - 6.7 6.1 17.3 1.8 8.0 4.8 2.6 1 1 1 3 3 3 0 Allexivirus 40kDa protein Sre PF03125.18 CDJ96055.1 - 2.6e-10 40.0 10.1 2.6e-10 40.0 10.1 2.4 1 1 1 2 2 2 1 C. elegans Sre G protein-coupled chemoreceptor 7TM_GPCR_Srab PF10292.9 CDJ96055.1 - 2.6e-07 29.9 13.8 0.00015 20.8 13.8 2.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor MADF_DNA_bdg PF10545.9 CDJ96056.1 - 0.016 15.5 0.1 0.035 14.4 0.1 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PCI PF01399.27 CDJ96057.1 - 4e-08 33.7 0.1 4e-08 33.7 0.1 3.0 3 1 0 3 3 3 1 PCI domain Pkinase PF00069.25 CDJ96058.1 - 7.2e-26 91.1 0.0 1.1e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ96058.1 - 2.9e-10 39.9 0.0 3.9e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HSP9_HSP12 PF04119.12 CDJ96060.1 - 0.95 9.9 6.5 0.96 9.9 1.4 2.2 2 0 0 2 2 2 0 Heat shock protein 9/12 Ank_2 PF12796.7 CDJ96061.1 - 3.3e-107 351.2 22.6 2.3e-17 63.4 0.6 9.1 2 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ96061.1 - 4.3e-104 336.8 39.9 1e-06 28.9 0.4 17.2 17 0 0 17 17 17 16 Ankyrin repeat Ank_4 PF13637.6 CDJ96061.1 - 1.5e-101 331.6 31.1 8.2e-14 51.8 0.4 12.5 3 2 10 14 14 14 14 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ96061.1 - 3.4e-96 314.0 29.9 1.3e-12 47.7 0.1 13.5 4 4 10 14 14 14 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ96061.1 - 1.8e-93 295.1 22.6 1.9e-06 27.8 0.0 17.2 17 0 0 17 17 17 15 Ankyrin repeat AnkUBD PF18418.1 CDJ96061.1 - 0.0014 18.7 0.5 1e+02 3.1 0.0 6.1 5 2 4 9 9 9 0 Ankyrin ubiquitin-binding domain BTRD1 PF17660.1 CDJ96061.1 - 0.057 13.2 0.0 8.9 6.2 0.0 3.7 4 0 0 4 4 4 0 Bacterial tandem repeat domain 1 PK_C PF02887.16 CDJ96061.1 - 0.069 13.4 0.1 1.9 8.8 0.0 3.1 2 1 0 2 2 2 0 Pyruvate kinase, alpha/beta domain Shigella_OspC PF06128.11 CDJ96061.1 - 0.075 12.7 0.0 33 4.1 0.0 3.7 4 0 0 4 4 4 0 Shigella flexneri OspC protein Cyclin_N PF00134.23 CDJ96061.1 - 0.13 12.0 0.2 18 5.1 0.0 3.7 5 0 0 5 5 5 0 Cyclin, N-terminal domain MSC PF09402.10 CDJ96062.1 - 4.5e-08 32.9 0.1 8.5e-08 32.0 0.0 1.4 1 1 1 2 2 2 1 Man1-Src1p-C-terminal domain Vma12 PF11712.8 CDJ96062.1 - 0.0072 16.4 0.2 0.012 15.7 0.2 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF5305 PF17231.2 CDJ96062.1 - 0.083 12.3 0.8 1.6 8.1 0.1 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5305) DUF4327 PF14217.6 CDJ96062.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4327) DUF4059 PF13268.6 CDJ96062.1 - 0.32 11.4 3.7 1.4 9.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) Sigma_reg_N PF13800.6 CDJ96062.1 - 1.5 9.2 4.6 4.3 7.7 0.0 2.3 1 1 1 2 2 2 0 Sigma factor regulator N-terminal HIP1_clath_bdg PF16515.5 CDJ96063.1 - 0.037 14.6 0.3 0.037 14.6 0.3 3.7 4 1 0 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Tup_N PF08581.10 CDJ96063.1 - 8.8 6.7 10.9 5.2 7.4 0.1 3.7 3 2 1 4 4 4 0 Tup N-terminal SCVP PF17619.2 CDJ96064.1 - 3e-24 85.7 2.0 4.3e-19 69.2 0.5 2.2 2 0 0 2 2 2 2 Secreted clade V proteins SCVP PF17619.2 CDJ96065.1 - 2.1e-39 134.3 5.3 9.2e-20 71.3 1.3 3.0 2 0 0 2 2 2 2 Secreted clade V proteins DEAD PF00270.29 CDJ96065.1 - 1.5e-30 106.3 0.0 2.6e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ96065.1 - 2.4e-10 40.7 0.0 6.2e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CLN3 PF02487.17 CDJ96065.1 - 0.029 13.4 0.7 0.062 12.4 0.7 1.6 1 1 0 1 1 1 0 CLN3 protein DUF936 PF06075.12 CDJ96065.1 - 2.9 6.7 15.4 5.5 5.8 15.4 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Peptidase_S24 PF00717.23 CDJ96066.1 - 4.5e-11 42.6 0.0 7e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Phage_C PF12025.8 CDJ96066.1 - 0.028 14.2 0.1 0.046 13.6 0.1 1.3 1 0 0 1 1 1 0 Phage protein C Sh_2 PF17512.2 CDJ96066.1 - 0.13 12.0 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 Metapneumovirus Small hydrophobic protein Sec7 PF01369.20 CDJ96067.1 - 1.4e-64 217.1 0.1 2.3e-64 216.4 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CDJ96067.1 - 1e-27 97.0 3.6 1e-27 97.0 3.6 2.4 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 CDJ96067.1 - 1e-06 28.6 0.0 3e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 CDJ96067.1 - 0.14 12.0 0.0 8 6.4 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) DUF1075 PF06388.11 CDJ96069.1 - 4.3e-07 30.0 0.2 5.5e-07 29.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1075) Patched PF02460.18 CDJ96070.1 - 6.2e-113 378.5 21.5 1.7e-112 377.0 21.5 1.6 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 CDJ96070.1 - 4.1e-26 91.7 1.4 4.1e-26 91.7 1.4 2.5 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Arm PF00514.23 CDJ96071.1 - 4.4e-57 188.5 19.5 3.9e-10 39.4 0.1 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 CDJ96071.1 - 3e-14 52.3 0.9 2.8e-13 49.2 0.5 2.4 2 0 0 2 2 2 1 Atypical Arm repeat IBB PF01749.20 CDJ96071.1 - 4.4e-14 52.7 2.4 1.6e-13 50.9 1.8 2.3 2 0 0 2 2 2 1 Importin beta binding domain HEAT_EZ PF13513.6 CDJ96071.1 - 3.7e-13 49.7 12.0 0.00036 20.9 0.6 6.2 4 2 2 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 CDJ96071.1 - 2.6e-12 47.0 5.0 0.018 15.4 1.6 5.8 2 1 5 7 7 7 4 HEAT repeats HEAT PF02985.22 CDJ96071.1 - 1e-08 34.7 8.0 0.04 14.2 0.1 7.8 9 0 0 9 9 8 1 HEAT repeat RICTOR_V PF14668.6 CDJ96071.1 - 0.00019 21.6 2.3 1.1 9.6 0.0 4.6 4 1 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Vac14_Fab1_bd PF12755.7 CDJ96071.1 - 0.0017 18.9 0.0 2.3 8.9 0.0 4.1 3 3 2 5 5 5 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 CDJ96071.1 - 0.0092 15.6 1.3 0.38 10.3 0.0 3.5 2 1 1 4 4 4 1 CLASP N terminal Cnd1 PF12717.7 CDJ96071.1 - 0.011 15.8 4.9 0.29 11.2 0.0 3.7 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 CDJ96071.1 - 0.017 15.2 0.2 5.3 7.2 0.0 3.8 3 1 0 4 4 4 0 V-ATPase subunit H FANCI_S3 PF14677.6 CDJ96071.1 - 0.05 13.3 0.2 0.16 11.7 0.2 1.8 1 0 0 1 1 1 0 FANCI solenoid 3 ParcG PF10274.9 CDJ96071.1 - 0.079 13.1 0.0 0.46 10.6 0.0 2.1 2 0 0 2 2 2 0 Parkin co-regulated protein HEAT_PBS PF03130.16 CDJ96071.1 - 0.14 12.9 4.3 30 5.7 0.2 4.8 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Methyltransf_21 PF05050.12 CDJ96072.1 - 3.1e-13 50.1 0.0 4.5e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain SCVP PF17619.2 CDJ96073.1 - 2.8e-42 143.5 5.2 1.2e-23 83.8 0.7 2.2 2 0 0 2 2 2 2 Secreted clade V proteins Glyco_hydro_2_N PF02837.18 CDJ96073.1 - 0.096 12.6 0.2 0.64 9.9 0.2 2.0 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain SCVP PF17619.2 CDJ96074.1 - 1.8e-31 108.8 1.0 1.8e-14 54.4 0.2 2.2 2 0 0 2 2 2 2 Secreted clade V proteins PIF1 PF05970.14 CDJ96076.1 - 1e-102 344.1 0.0 1.4e-102 343.5 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 CDJ96076.1 - 9.9e-62 208.5 0.0 9.9e-62 208.5 0.0 3.3 3 2 1 4 4 4 1 Helitron helicase-like domain at N-terminus AAA_19 PF13245.6 CDJ96076.1 - 8.3e-05 23.0 0.0 0.00026 21.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 CDJ96076.1 - 0.00066 17.8 0.0 0.0013 16.8 0.0 1.4 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 CDJ96076.1 - 0.0025 17.6 0.0 2.8 7.6 0.0 2.7 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 CDJ96076.1 - 0.0068 16.4 0.0 0.018 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CDJ96076.1 - 0.012 15.6 0.0 0.034 14.1 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 CDJ96076.1 - 0.032 14.1 0.0 0.098 12.5 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain RRM_1 PF00076.22 CDJ96077.1 - 2.9e-22 78.3 0.7 1e-15 57.3 0.2 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phage_TAC_13 PF16459.5 CDJ96077.1 - 0.0011 19.3 0.0 1.8 9.0 0.0 2.4 2 0 0 2 2 2 2 Phage tail assembly chaperone, TAC RRM_Rrp7 PF17799.1 CDJ96077.1 - 0.13 12.1 0.1 0.99 9.2 0.0 2.3 2 1 1 3 3 3 0 Rrp7 RRM-like N-terminal domain ANAPC_CDC26 PF10471.9 CDJ96078.1 - 0.00016 22.4 0.7 0.00026 21.8 0.7 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 zf-C3HC4_3 PF13920.6 CDJ96079.1 - 1.2e-14 53.8 10.3 3e-14 52.6 10.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDJ96079.1 - 1.7e-07 31.0 10.9 4.2e-07 29.7 10.9 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CDJ96079.1 - 2.5e-05 24.5 14.6 4.5e-05 23.7 12.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ96079.1 - 0.0015 18.3 12.2 0.0044 16.8 12.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ96079.1 - 0.0053 16.7 12.7 0.012 15.5 12.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 CDJ96079.1 - 0.17 11.7 9.5 0.42 10.4 9.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 CDJ96079.1 - 0.42 10.4 8.0 0.4 10.5 2.4 3.2 3 0 0 3 3 3 0 RING-like zinc finger zf-RING_UBOX PF13445.6 CDJ96079.1 - 0.67 10.0 8.5 12 6.0 5.3 2.5 2 0 0 2 2 2 0 RING-type zinc-finger ABA_GPCR PF12430.8 CDJ96080.1 - 7.8e-41 139.8 11.2 7.8e-41 139.8 11.2 2.4 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 CDJ96080.1 - 1.7e-24 85.7 1.2 2.8e-24 85.0 0.3 1.9 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal CytB6-F_Fe-S PF08802.10 CDJ96080.1 - 0.41 10.7 3.3 0.54 10.3 0.2 2.4 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit RVT_1 PF00078.27 CDJ96081.1 - 1.8e-07 30.9 0.0 2.7e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Aminotran_4 PF01063.19 CDJ96082.1 - 1.3e-32 113.5 0.0 1.6e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV 7tm_3 PF00003.22 CDJ96083.1 - 3.5e-26 92.4 8.7 5.6e-26 91.7 8.7 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 CDJ96083.1 - 4.6e-12 45.7 10.9 9.8e-12 44.7 10.9 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR ANF_receptor PF01094.28 CDJ96083.1 - 1.1e-05 24.7 0.0 1.5e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Ephrin_rec_like PF07699.13 CDJ96083.1 - 2.2 8.1 12.4 2.8 7.8 5.9 2.5 1 1 1 2 2 2 0 Putative ephrin-receptor like SRP19 PF01922.17 CDJ96084.1 - 0.055 14.4 0.1 0.074 14.0 0.1 1.2 1 0 0 1 1 1 0 SRP19 protein YtxH PF12732.7 CDJ96085.1 - 0.014 15.9 0.2 0.018 15.5 0.2 1.3 1 1 0 1 1 1 0 YtxH-like protein Phage_term_smal PF05944.12 CDJ96085.1 - 0.028 14.4 0.0 0.032 14.2 0.0 1.1 1 0 0 1 1 1 0 Phage small terminase subunit BMFP PF04380.13 CDJ96085.1 - 0.09 13.3 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Membrane fusogenic activity UDPGT PF00201.18 CDJ96086.1 - 3.8e-38 131.5 0.0 5.7e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDJ96086.1 - 0.0054 16.7 0.0 0.0093 16.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Neur_chan_LBD PF02931.23 CDJ96087.1 - 3.2e-13 49.6 0.0 4.5e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Troponin PF00992.20 CDJ96088.1 - 1.4e-06 28.6 6.0 1.4e-06 28.6 6.0 3.9 3 1 0 4 4 4 1 Troponin Mitofilin PF09731.9 CDJ96088.1 - 3.6 6.3 51.9 5.3 5.8 51.9 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein FeoB_associated PF12669.7 CDJ96089.1 - 0.076 13.4 1.8 0.11 12.9 1.8 1.2 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein TIL PF01826.17 CDJ96090.1 - 2.5e-33 114.1 72.7 3e-12 46.6 18.0 3.2 3 0 0 3 3 3 3 Trypsin Inhibitor like cysteine rich domain cEGF PF12662.7 CDJ96090.1 - 0.12 12.4 24.4 0.54 10.2 0.4 4.6 4 1 0 4 4 4 0 Complement Clr-like EGF-like CAP PF00188.26 CDJ96091.1 - 4.8e-16 59.7 0.4 7e-16 59.2 0.4 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CNOT1_TTP_bind PF16417.5 CDJ96092.1 - 4.4e-45 153.2 0.0 6e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain Sec10 PF07393.11 CDJ96092.1 - 0.021 13.2 0.0 0.027 12.9 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 Cation_ATPase_C PF00689.21 CDJ96093.1 - 1.4e-42 145.5 6.3 1.4e-42 145.5 6.3 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CDJ96093.1 - 8.1e-30 103.7 6.5 4.9e-24 84.8 1.2 3.1 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase PF13246.6 CDJ96093.1 - 1.6e-16 60.2 0.0 4.9e-16 58.6 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) ATP_Ca_trans_C PF12424.8 CDJ96093.1 - 4.7e-16 59.0 0.8 2.7e-15 56.5 0.6 2.5 2 0 0 2 2 2 1 Plasma membrane calcium transporter ATPase C terminal Cation_ATPase_N PF00690.26 CDJ96093.1 - 1.9e-15 56.3 0.0 1.4e-13 50.3 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 CDJ96093.1 - 1.1e-14 55.3 0.1 4.4e-14 53.3 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDJ96093.1 - 1.2e-06 28.5 3.0 0.0001 22.1 0.2 2.6 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Na_K-ATPase PF00287.18 CDJ96097.1 - 1.1e-14 54.3 0.0 1.3e-14 54.1 0.0 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain HTH_48 PF17906.1 CDJ96098.1 - 6.1e-12 45.5 0.1 1e-11 44.8 0.1 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase Transposase_1 PF01359.18 CDJ96098.1 - 1.1e-06 28.3 0.4 1.1e-06 28.3 0.4 1.6 2 0 0 2 2 2 1 Transposase (partial DDE domain) HTH_28 PF13518.6 CDJ96098.1 - 3.6e-06 27.0 1.9 0.062 13.4 0.0 2.5 3 0 0 3 3 2 2 Helix-turn-helix domain HTH_AsnC-type PF13404.6 CDJ96098.1 - 0.00052 19.8 0.5 0.001 18.8 0.5 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_23 PF13384.6 CDJ96098.1 - 0.00056 19.6 0.0 0.81 9.6 0.0 2.3 2 0 0 2 2 2 2 Homeodomain-like domain HTH_24 PF13412.6 CDJ96098.1 - 0.00066 19.2 0.3 0.0042 16.6 0.1 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 CDJ96098.1 - 0.0011 18.8 0.2 0.0027 17.6 0.1 1.6 2 0 0 2 2 1 1 MarR family HTH_5 PF01022.20 CDJ96098.1 - 0.011 15.6 0.0 0.028 14.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_psq PF05225.16 CDJ96098.1 - 0.028 14.1 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Rrf2 PF02082.20 CDJ96098.1 - 0.06 13.7 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator HTH_Tnp_IS630 PF01710.16 CDJ96098.1 - 0.064 13.3 0.1 0.097 12.7 0.1 1.3 1 0 0 1 1 1 0 Transposase HTH_11 PF08279.12 CDJ96098.1 - 0.067 13.2 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 HTH domain MarR_2 PF12802.7 CDJ96098.1 - 0.083 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 MarR family Arg_repressor PF01316.21 CDJ96098.1 - 0.088 12.6 0.1 0.43 10.4 0.1 2.0 2 0 0 2 2 2 0 Arginine repressor, DNA binding domain HTH_27 PF13463.6 CDJ96098.1 - 0.14 12.7 0.0 0.22 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_DeoR PF08220.12 CDJ96098.1 - 0.17 11.6 0.4 4.6 7.1 0.1 2.2 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain HTH_20 PF12840.7 CDJ96098.1 - 0.18 11.9 0.2 0.35 11.0 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3460 PF11943.8 CDJ96098.1 - 0.43 10.9 2.5 26 5.2 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3460) Dickkopf_N PF04706.12 CDJ96099.1 - 0.0004 20.8 5.3 0.0004 20.8 5.3 4.5 3 2 0 4 4 4 1 Dickkopf N-terminal cysteine-rich region FA_hydroxylase PF04116.13 CDJ96101.1 - 4.7e-20 72.3 16.5 4.7e-20 72.3 16.5 1.8 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily Histone PF00125.24 CDJ96102.1 - 2.4e-06 27.9 0.1 3.1e-06 27.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 SPOC PF07744.13 CDJ96103.1 - 3.5e-23 82.2 3.6 8.5e-23 80.9 0.0 2.7 2 0 0 2 2 2 1 SPOC domain RRM_1 PF00076.22 CDJ96103.1 - 1.1e-20 73.3 0.0 4.5e-10 39.2 0.0 4.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ96103.1 - 4.3e-06 26.5 0.2 0.0021 17.9 0.0 4.0 5 0 0 5 5 5 1 Occluded RNA-recognition motif RRM_7 PF16367.5 CDJ96103.1 - 3.2e-05 24.0 0.1 3.5 7.8 0.0 4.3 3 0 0 3 3 3 2 RNA recognition motif Actin PF00022.19 CDJ96105.1 - 2e-126 421.9 0.0 1.3e-125 419.3 0.0 1.8 1 1 0 1 1 1 1 Actin SET PF00856.28 CDJ96106.1 - 3.7e-08 34.0 0.0 9.8e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 SET domain V_ATPase_I PF01496.19 CDJ96107.1 - 0.038 11.9 5.4 0.074 11.0 5.4 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF5384 PF17358.2 CDJ96107.1 - 1.7 8.7 9.1 0.99 9.4 6.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5384) Peptidase_C14 PF00656.22 CDJ96108.1 - 1.4e-41 143.1 0.0 1.9e-41 142.7 0.0 1.1 1 0 0 1 1 1 1 Caspase domain CARD PF00619.21 CDJ96108.1 - 1e-12 47.9 0.2 9.6e-12 44.8 0.0 2.4 2 0 0 2 2 2 1 Caspase recruitment domain CARD_2 PF16739.5 CDJ96108.1 - 0.00015 21.7 0.0 0.00032 20.6 0.0 1.6 1 0 0 1 1 1 1 Caspase recruitment domain DUF1242 PF06842.12 CDJ96109.1 - 0.017 14.9 0.8 0.041 13.7 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1242) PRP1_N PF06424.12 CDJ96110.1 - 1.5e-54 184.4 7.1 1.5e-54 184.4 7.1 1.8 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 CDJ96110.1 - 2.6e-10 40.3 2.0 0.11 13.4 0.1 5.3 2 1 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ96110.1 - 0.00058 20.3 0.3 16 6.1 0.0 4.4 3 1 3 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ96110.1 - 0.013 15.8 0.0 4.7 7.8 0.0 3.9 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ96110.1 - 0.038 14.1 7.4 31 5.0 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ96110.1 - 0.08 13.6 0.2 1.4e+02 3.3 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat Hen1_Lam_C PF18441.1 CDJ96110.1 - 0.14 12.0 0.0 0.85 9.5 0.0 2.2 1 1 1 2 2 2 0 Hen1 La-motif C-terminal domain TPR_11 PF13414.6 CDJ96110.1 - 0.22 11.2 3.1 11 5.8 1.5 3.2 3 0 0 3 3 3 0 TPR repeat DUF1835 PF08874.10 CDJ96110.1 - 2.5 8.3 6.5 21 5.3 1.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1835) Ssu72 PF04722.13 CDJ96111.1 - 6.6e-79 263.9 0.1 7.4e-79 263.8 0.1 1.0 1 0 0 1 1 1 1 Ssu72-like protein DUF1638 PF07796.11 CDJ96111.1 - 0.044 13.8 0.1 0.063 13.3 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1638) DAGK_cat PF00781.24 CDJ96112.1 - 3.7e-17 62.1 0.0 6.5e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Tim54 PF11711.8 CDJ96112.1 - 0.095 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NAD_kinase PF01513.21 CDJ96112.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 ATP-NAD kinase PcrB PF01884.17 CDJ96112.1 - 0.17 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 PcrB family EloA-BP1 PF15870.5 CDJ96113.1 - 1.6e-19 70.8 0.1 1.6e-19 70.8 0.1 3.0 2 2 1 3 3 3 1 ElonginA binding-protein 1 COX5A PF02284.16 CDJ96113.1 - 1.7 8.7 5.7 1.9 8.5 0.0 3.0 3 0 0 3 3 3 0 Cytochrome c oxidase subunit Va PGM_PMM_I PF02878.16 CDJ96114.1 - 3.6e-35 120.7 0.2 5.4e-35 120.1 0.2 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 CDJ96114.1 - 4.1e-29 101.1 0.0 8.5e-29 100.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CDJ96114.1 - 2.3e-16 60.3 0.0 8.2e-16 58.5 0.0 2.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 CDJ96114.1 - 1.8e-07 31.2 0.0 4.7e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain ANAPC4_WD40 PF12894.7 CDJ96116.1 - 4.9e-12 46.0 0.0 0.11 12.9 0.0 5.1 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ96116.1 - 7.9e-06 26.5 0.2 1.4 9.9 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat PD40 PF07676.12 CDJ96116.1 - 0.0074 16.2 0.0 1.3 9.0 0.0 2.9 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Phospholip_A2_1 PF00068.19 CDJ96117.1 - 4.9e-28 97.8 15.2 6.1e-28 97.5 15.2 1.1 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_1 PF00068.19 CDJ96118.1 - 9.4e-29 100.1 12.7 1.1e-28 99.9 12.7 1.1 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_2 PF05826.12 CDJ96118.1 - 0.86 9.9 17.9 2.2 8.5 11.5 2.3 1 1 1 2 2 2 0 Phospholipase A2 zf-RING_5 PF14634.6 CDJ96119.1 - 8.9e-08 32.0 10.5 1.6e-07 31.1 10.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDJ96119.1 - 7.2e-06 25.8 11.6 1.7e-05 24.6 11.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 CREPT PF16566.5 CDJ96119.1 - 0.00027 21.1 3.5 0.00043 20.5 3.5 1.3 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour PRP9_N PF16958.5 CDJ96119.1 - 0.004 17.2 3.1 0.006 16.6 3.1 1.2 1 0 0 1 1 1 1 Pre-mRNA-splicing factor PRP9 N-terminus zf-C3HC4 PF00097.25 CDJ96119.1 - 0.0096 15.8 8.1 0.021 14.7 8.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ96119.1 - 0.012 15.9 9.1 0.024 15.0 9.1 1.5 1 0 0 1 1 1 0 Ring finger domain SlyX PF04102.12 CDJ96119.1 - 0.034 14.8 0.2 0.086 13.5 0.2 1.6 1 0 0 1 1 1 0 SlyX zf-C3H2C3 PF17122.5 CDJ96119.1 - 1.1 9.4 7.8 3.4 7.8 1.7 2.6 2 0 0 2 2 2 0 Zinc-finger DUF4164 PF13747.6 CDJ96119.1 - 1.3 9.4 7.4 6.7 7.1 5.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) zf-C3HC4_4 PF15227.6 CDJ96119.1 - 1.3 9.3 9.7 0.93 9.7 7.1 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF963 PF06131.11 CDJ96119.1 - 1.7 8.1 5.6 0.32 10.4 1.4 2.0 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) ZZ PF00569.17 CDJ96119.1 - 3.2 7.7 8.9 0.29 11.0 3.4 2.2 1 1 0 1 1 1 0 Zinc finger, ZZ type Ribosomal_S16 PF00886.19 CDJ96120.1 - 2e-14 53.4 0.0 3.7e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 SEFIR PF08357.11 CDJ96121.1 - 9.4e-12 45.4 0.0 1.5e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 SEFIR domain zf-C2H2 PF00096.26 CDJ96122.1 - 2e-11 43.6 70.4 0.00042 20.6 2.1 9.8 10 0 0 10 10 10 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ96122.1 - 2.2e-09 37.3 64.8 0.0035 18.1 1.0 9.4 9 0 0 9 9 9 6 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CDJ96122.1 - 8.1e-09 35.1 38.3 8e-05 22.3 2.9 7.3 7 0 0 7 7 7 3 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 CDJ96122.1 - 0.00018 22.2 18.7 0.0015 19.2 1.4 4.1 2 1 1 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 CDJ96122.1 - 0.00078 19.8 1.2 0.00078 19.8 1.2 8.8 8 1 0 8 8 7 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 CDJ96122.1 - 0.015 15.3 1.5 0.015 15.3 1.5 6.5 7 0 0 7 7 6 0 C2H2-type zinc finger PX PF00787.24 CDJ96122.1 - 0.049 13.6 0.1 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 PX domain Stn1_C PF12659.7 CDJ96122.1 - 0.16 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Telomere capping C-terminal wHTH IL5 PF02025.15 CDJ96122.1 - 0.21 11.9 0.9 1.4 9.3 0.2 2.2 2 0 0 2 2 2 0 Interleukin 5 zf-C2H2_12 PF18658.1 CDJ96122.1 - 0.24 11.0 26.0 1.7 8.2 0.1 5.6 3 1 1 5 5 5 0 Zinc-finger C2H2-type zf-RAG1 PF10426.9 CDJ96122.1 - 0.56 10.4 0.0 0.56 10.4 0.0 3.9 5 0 0 5 5 5 0 Recombination-activating protein 1 zinc-finger domain OrsD PF12013.8 CDJ96122.1 - 0.7 10.4 35.2 3.6 8.1 0.2 7.5 3 2 2 6 6 6 0 Orsellinic acid/F9775 biosynthesis cluster protein D E_Pc_C PF06752.12 CDJ96122.1 - 1.5 8.9 5.8 0.92 9.6 0.1 2.3 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus zf-C2H2_2 PF12756.7 CDJ96122.1 - 2.2 8.7 34.1 4.8 7.6 0.6 6.2 2 2 3 6 6 6 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 CDJ96122.1 - 7.6 6.3 30.0 0.63 9.7 0.6 5.7 4 1 2 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain EF-hand_1 PF00036.32 CDJ96123.1 - 3.3e-30 101.3 16.9 1.1e-08 34.1 0.5 4.1 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CDJ96123.1 - 7.7e-27 90.9 10.7 6.4e-09 35.0 0.3 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 CDJ96123.1 - 3.4e-26 91.5 5.1 1.7e-13 50.8 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ96123.1 - 3.5e-23 81.2 12.1 1.6e-10 40.7 1.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CDJ96123.1 - 2.3e-21 74.3 13.6 3e-09 35.9 0.5 4.3 4 0 0 4 4 4 4 EF hand Dockerin_1 PF00404.18 CDJ96123.1 - 9.2e-09 35.4 0.6 1.2e-05 25.4 0.9 2.8 3 0 0 3 3 3 2 Dockerin type I domain EF-hand_4 PF12763.7 CDJ96123.1 - 2e-07 30.9 1.4 0.0077 16.2 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CDJ96123.1 - 6.8e-06 26.4 0.2 0.1 12.9 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CDJ96123.1 - 0.0014 18.9 0.1 0.21 11.9 0.0 2.4 1 1 2 3 3 3 2 EF-hand domain Caleosin PF05042.13 CDJ96123.1 - 0.0042 17.0 0.0 3.6 7.5 0.0 2.9 3 1 0 3 3 3 2 Caleosin related protein EAP30 PF04157.16 CDJ96123.1 - 0.012 15.0 0.0 0.97 8.7 0.0 2.2 1 1 0 1 1 1 0 EAP30/Vps36 family UPF0154 PF03672.13 CDJ96123.1 - 0.032 14.3 0.2 1.9 8.5 0.1 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF2666 PF10869.8 CDJ96123.1 - 0.061 13.5 0.1 1.5 9.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) SRP54_N PF02881.19 CDJ96123.1 - 0.24 11.6 3.4 6.6 7.0 0.1 3.1 3 0 0 3 3 3 0 SRP54-type protein, helical bundle domain ABC_tran PF00005.27 CDJ96125.1 - 2.2e-20 73.6 0.0 3.4e-18 66.5 0.0 2.7 3 0 0 3 3 3 1 ABC transporter ABC2_membrane_3 PF12698.7 CDJ96125.1 - 2.3e-18 66.4 58.4 5.8e-12 45.4 20.7 3.5 4 0 0 4 4 4 3 ABC-2 family transporter protein SMC_N PF02463.19 CDJ96125.1 - 0.00034 20.1 0.0 0.22 10.9 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CDJ96125.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ATP-synt_ab PF00006.25 CDJ96125.1 - 0.1 12.3 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain dUTPase PF00692.19 CDJ96127.1 - 1.1e-38 131.8 0.0 1.5e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 dUTPase Got1 PF04178.12 CDJ96128.1 - 2.3e-15 57.0 18.3 2.6e-15 56.8 17.5 1.5 2 0 0 2 2 2 1 Got1/Sft2-like family DB PF01682.19 CDJ96129.1 - 2.6e-15 56.5 11.3 3.8e-15 56.0 11.3 1.3 1 0 0 1 1 1 1 DB module Peptidase_M13_N PF05649.13 CDJ96130.1 - 1.7e-86 291.4 0.1 2e-86 291.1 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 CDJ96130.1 - 1.5e-65 220.6 0.0 2.4e-65 220.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 WD40 PF00400.32 CDJ96131.1 - 2.7e-06 28.0 4.5 3.4 8.7 0.1 6.2 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ96131.1 - 2e-05 24.8 1.0 5.2 7.4 0.1 4.2 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_A17 PF05380.13 CDJ96132.1 - 9e-39 133.1 0.6 1.7e-38 132.2 0.6 1.5 1 0 0 1 1 1 1 Pao retrotransposon peptidase DUF1759 PF03564.15 CDJ96132.1 - 3.9e-28 98.3 3.6 1.8e-27 96.1 3.6 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 CDJ96132.1 - 1e-05 25.4 0.0 3e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Putative peptidase (DUF1758) RVT_1 PF00078.27 CDJ96132.1 - 0.00017 21.1 0.2 0.0014 18.2 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CDJ96132.1 - 0.00073 20.1 0.0 0.0018 18.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ96132.1 - 0.0012 19.4 0.0 0.0026 18.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Leg1 PF05612.12 CDJ96132.1 - 0.49 9.5 4.2 0.16 11.0 0.3 2.0 2 0 0 2 2 2 0 Leg1 rve PF00665.26 CDJ96133.1 - 0.019 15.2 0.0 0.035 14.3 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain PUB_1 PF18486.1 CDJ96133.1 - 0.03 14.2 0.2 0.065 13.1 0.2 1.6 1 0 0 1 1 1 0 PNGase/UBA- or UBX-containing domain Glyco_hydro_19 PF00182.19 CDJ96135.1 - 1.2e-32 113.7 2.5 3.3e-24 86.1 0.2 2.2 1 1 1 2 2 2 2 Chitinase class I Kunitz_BPTI PF00014.23 CDJ96136.1 - 5.2e-15 55.4 3.5 5.2e-15 55.4 3.5 2.4 2 0 0 2 2 2 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Lustrin_cystein PF14625.6 CDJ96136.1 - 0.0058 17.0 8.8 0.0058 17.0 8.8 3.7 2 1 2 4 4 4 2 Lustrin, cysteine-rich repeated domain zf_CCCH_4 PF18345.1 CDJ96136.1 - 0.36 10.9 7.1 5.9 7.1 0.7 3.5 3 0 0 3 3 3 0 Zinc finger domain DUF3390 PF11870.8 CDJ96137.1 - 0.022 15.1 1.3 4.6 7.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3390) Antimicrobial14 PF08109.11 CDJ96137.1 - 0.096 12.7 0.2 28 4.9 0.0 2.9 2 2 0 2 2 2 0 Lactocin 705 family Kunitz_BPTI PF00014.23 CDJ96138.1 - 6e-14 52.0 7.2 6e-14 52.0 7.2 2.3 2 0 0 2 2 2 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Lustrin_cystein PF14625.6 CDJ96138.1 - 0.025 14.9 7.0 0.025 14.9 7.0 2.7 3 0 0 3 3 3 0 Lustrin, cysteine-rich repeated domain Kunitz_BPTI PF00014.23 CDJ96139.1 - 6.3e-13 48.7 9.4 3.4e-12 46.4 9.4 2.4 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Lustrin_cystein PF14625.6 CDJ96139.1 - 0.011 16.1 7.0 0.011 16.1 7.0 3.7 3 1 1 4 4 4 0 Lustrin, cysteine-rich repeated domain Phage_terminase PF10668.9 CDJ96139.1 - 0.16 12.0 0.6 17 5.5 0.2 2.5 2 0 0 2 2 2 0 Phage terminase small subunit Kunitz_BPTI PF00014.23 CDJ96140.1 - 6.4e-14 51.9 7.4 6.4e-14 51.9 7.4 2.1 2 0 0 2 2 2 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Lustrin_cystein PF14625.6 CDJ96140.1 - 0.016 15.6 7.9 0.016 15.6 7.9 3.5 3 0 0 3 3 3 0 Lustrin, cysteine-rich repeated domain G-alpha PF00503.20 CDJ96142.1 - 2.8e-100 335.9 10.3 3.5e-100 335.6 10.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDJ96142.1 - 7.2e-14 51.6 4.8 6.5e-12 45.3 1.6 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family AAA_16 PF13191.6 CDJ96142.1 - 0.0016 18.9 0.0 0.0035 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 CDJ96142.1 - 0.0039 17.1 1.6 0.12 12.3 0.2 2.6 1 1 1 3 3 3 1 Rad17 P-loop domain Roc PF08477.13 CDJ96142.1 - 0.0046 17.2 0.1 1.7 8.8 0.1 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CDJ96142.1 - 0.011 15.3 2.2 2.4 7.6 0.8 2.7 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CDJ96142.1 - 0.012 15.0 1.3 0.012 15.0 1.3 3.0 3 1 0 3 3 3 0 Gtr1/RagA G protein conserved region DUF1955 PF09205.10 CDJ96142.1 - 0.012 15.3 1.2 1.1 9.0 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1955) TniB PF05621.11 CDJ96142.1 - 0.023 14.1 0.1 0.052 13.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial TniB protein ShK PF01549.24 CDJ96143.1 - 1.8e-05 25.2 9.8 0.032 14.8 4.6 2.2 2 0 0 2 2 2 2 ShK domain-like ShK PF01549.24 CDJ96144.1 - 2.3e-28 98.4 46.8 4.6e-11 43.1 7.1 3.9 4 0 0 4 4 4 3 ShK domain-like HTH_32 PF13565.6 CDJ96145.1 - 0.012 16.2 0.1 0.014 16.0 0.1 1.2 1 0 0 1 1 1 0 Homeodomain-like domain adh_short_C2 PF13561.6 CDJ96146.1 - 1e-11 44.8 0.0 1.4e-11 44.4 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CAP PF00188.26 CDJ96146.1 - 3.4e-08 34.4 0.0 5.4e-08 33.7 0.0 1.4 1 1 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ96146.1 - 0.042 14.1 0.0 0.061 13.6 0.0 1.3 1 0 0 1 1 1 0 Ancylostoma-associated secreted protein related CAP PF00188.26 CDJ96147.1 - 2.1e-08 35.1 1.0 2.3e-08 34.9 1.0 1.0 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CDJ96148.1 - 6.9e-10 39.8 5.6 1.6e-07 32.2 0.3 2.3 2 0 0 2 2 2 2 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ96148.1 - 0.036 14.3 0.7 0.12 12.7 0.1 2.2 2 1 0 2 2 2 0 Ancylostoma-associated secreted protein related adh_short PF00106.25 CDJ96149.1 - 1.1e-46 158.7 1.5 1.4e-46 158.4 1.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ96149.1 - 3.4e-37 128.2 1.0 4.3e-37 127.9 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ96149.1 - 1.8e-07 31.3 0.4 2.4e-07 30.8 0.4 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CDJ96149.1 - 6.6e-05 22.9 0.2 0.00012 22.1 0.1 1.5 2 0 0 2 2 2 1 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 CDJ96149.1 - 0.00097 18.5 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 CDJ96149.1 - 0.0012 18.4 0.1 0.0056 16.2 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.16 CDJ96149.1 - 0.0021 17.7 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 CDJ96149.1 - 0.0079 16.1 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 CDJ96149.1 - 0.0095 15.9 0.2 0.032 14.2 0.0 1.7 1 1 1 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF1776 PF08643.10 CDJ96149.1 - 0.024 14.0 0.1 0.029 13.7 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) TrkA_N PF02254.18 CDJ96149.1 - 0.024 14.9 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Lar_N PF09861.9 CDJ96149.1 - 0.036 13.2 0.0 0.073 12.2 0.0 1.5 1 0 0 1 1 1 0 Lactate racemase N-terminal domain NmrA PF05368.13 CDJ96149.1 - 0.046 13.3 0.0 0.056 13.0 0.0 1.2 1 1 0 1 1 1 0 NmrA-like family Eno-Rase_NADH_b PF12242.8 CDJ96149.1 - 0.056 13.2 0.5 0.12 12.1 0.5 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.17 CDJ96149.1 - 0.11 11.6 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Memo PF01875.17 CDJ96150.1 - 8.1e-94 313.8 0.0 9.4e-94 313.5 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein MRG PF05712.13 CDJ96151.1 - 5.4e-28 97.7 0.1 7.8e-28 97.1 0.1 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 CDJ96151.1 - 7.8e-06 25.7 3.0 2e-05 24.4 3.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF5102 PF17104.5 CDJ96151.1 - 0.0088 16.1 0.3 0.013 15.5 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) NTR PF01759.21 CDJ96151.1 - 0.028 14.2 0.4 0.045 13.6 0.4 1.3 1 0 0 1 1 1 0 UNC-6/NTR/C345C module La PF05383.17 CDJ96152.1 - 0.0097 15.9 0.1 0.025 14.6 0.1 1.7 1 0 0 1 1 1 1 La domain DUF2749 PF10907.8 CDJ96153.1 - 0.087 13.0 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) DUF4133 PF13571.6 CDJ96153.1 - 0.17 12.2 1.8 0.6 10.5 1.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4133) Neur_chan_memb PF02932.16 CDJ96154.1 - 0.00011 22.4 1.4 0.00026 21.1 1.4 1.6 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region CAP PF00188.26 CDJ96155.1 - 1.5e-16 61.4 3.6 1.5e-16 61.4 3.6 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ96155.1 - 0.018 15.4 0.2 0.018 15.4 0.2 2.1 2 2 0 2 2 2 0 Ancylostoma-associated secreted protein related Y_phosphatase PF00102.27 CDJ96156.1 - 4.5e-64 216.2 0.0 5.6e-64 215.9 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CDJ96156.1 - 0.00018 21.5 0.0 0.00022 21.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CDJ96156.1 - 0.0091 15.8 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CDJ96156.1 - 0.067 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate SEP PF08059.13 CDJ96157.1 - 1e-23 83.7 0.0 1.8e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 CDJ96157.1 - 5.8e-16 58.5 0.0 9.9e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 UBX domain Vpu PF00558.19 CDJ96157.1 - 0.79 9.5 3.4 8.9 6.2 0.1 2.3 2 0 0 2 2 2 0 Vpu protein Trypan_PARP PF05887.11 CDJ96158.1 - 2.8e-05 24.1 55.9 0.0047 16.9 28.6 2.1 1 1 1 2 2 2 2 Procyclic acidic repetitive protein (PARP) Peptidase_S10 PF00450.22 CDJ96159.1 - 1.3e-212 706.7 1.0 1.1e-109 367.7 0.3 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase Peptidase_S9 PF00326.21 CDJ96159.1 - 1.4e-12 47.6 0.2 0.022 14.2 0.0 4.8 4 1 0 4 4 4 4 Prolyl oligopeptidase family DAGK_acc PF00609.19 CDJ96161.1 - 1e-54 185.2 0.0 1.2e-53 181.7 0.0 2.5 3 0 0 3 3 3 1 Diacylglycerol kinase accessory domain RA PF00788.23 CDJ96161.1 - 2.5e-27 95.3 1.0 4.7e-14 52.8 0.1 2.7 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain C1_1 PF00130.22 CDJ96161.1 - 1.1e-26 92.4 49.7 7.4e-11 41.8 14.3 3.3 3 0 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) DAGK_cat PF00781.24 CDJ96161.1 - 4.7e-23 81.2 0.0 8.8e-23 80.3 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain TUG-UBL1 PF11470.8 CDJ96161.1 - 7.9e-05 22.8 0.0 0.25 11.6 0.0 2.7 2 0 0 2 2 2 2 TUG ubiquitin-like domain PHD PF00628.29 CDJ96161.1 - 0.013 15.4 8.0 0.013 15.4 8.0 3.7 3 0 0 3 3 3 0 PHD-finger Desmo_N PF06771.11 CDJ96161.1 - 0.1 13.0 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Viral Desmoplakin N-terminus C1_2 PF03107.16 CDJ96161.1 - 5.1 7.5 43.2 0.069 13.5 5.7 4.0 3 1 0 3 3 3 0 C1 domain Zf_RING PF16744.5 CDJ96161.1 - 6.2 7.0 36.8 0.13 12.4 6.6 3.9 4 0 0 4 4 4 0 KIAA1045 RING finger T6PP_N PF18572.1 CDJ96162.1 - 2.1e-26 91.7 0.0 4.1e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Hydrolase_3 PF08282.12 CDJ96162.1 - 0.091 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase F-box-like PF12937.7 CDJ96163.1 - 6.6e-08 32.3 0.7 1.8e-07 30.9 0.7 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDJ96163.1 - 5.4e-07 29.3 1.2 3.3e-06 26.8 0.3 2.7 2 0 0 2 2 2 1 F-box domain FbpA PF05833.11 CDJ96164.1 - 1e-37 130.0 2.6 1e-37 130.0 2.6 2.1 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 CDJ96164.1 - 3.5e-31 108.1 0.4 1.1e-30 106.5 0.0 2.1 2 0 0 2 2 2 1 NFACT protein RNA binding domain NFACT-C PF11923.8 CDJ96164.1 - 1.3e-20 73.3 0.0 1.3e-20 73.3 0.0 3.8 4 0 0 4 4 4 1 NFACT protein C-terminal domain Chromo PF00385.24 CDJ96165.1 - 4.3e-10 39.3 2.9 7.8e-10 38.5 2.9 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 CDJ96165.1 - 0.0066 16.3 0.9 0.014 15.3 0.9 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF3338 PF11819.8 CDJ96166.1 - 1.4e-19 70.5 1.0 2.3e-19 69.7 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3338) CAP PF00188.26 CDJ96168.1 - 8.8e-34 117.1 16.3 3.3e-17 63.5 3.5 2.2 2 0 0 2 2 2 2 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ96168.1 - 0.00031 21.0 2.5 0.061 13.6 0.0 2.9 3 0 0 3 3 3 2 Ancylostoma-associated secreted protein related Toxin_12 PF07740.12 CDJ96168.1 - 0.09 13.5 18.8 0.44 11.3 5.2 2.7 2 0 0 2 2 2 0 Ion channel inhibitory toxin SSP160 PF06933.11 CDJ96168.1 - 0.093 10.9 18.1 0.14 10.3 18.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Metallothio_Euk PF12749.7 CDJ96168.1 - 0.51 10.5 20.5 2.6 8.3 7.1 2.8 2 0 0 2 2 2 0 Eukaryotic metallothionein DUF3439 PF11921.8 CDJ96168.1 - 0.98 9.4 14.9 2.2 8.2 14.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) CAP PF00188.26 CDJ96169.1 - 1.8e-05 25.5 0.2 2.4e-05 25.2 0.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Asparaginase PF00710.20 CDJ96170.1 - 6.4e-64 215.0 0.0 1.1e-63 214.3 0.0 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 CDJ96170.1 - 4.6e-27 94.5 0.0 3.6e-26 91.6 0.0 2.3 2 1 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Ank_4 PF13637.6 CDJ96170.1 - 8.7e-27 93.2 1.7 2.2e-07 31.3 0.0 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ96170.1 - 7.3e-23 81.0 4.8 4.1e-08 33.7 0.3 2.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ96170.1 - 2.9e-17 62.5 0.9 1.9e-08 34.4 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ96170.1 - 1.9e-14 52.3 0.6 3.8e-05 23.7 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 CDJ96170.1 - 4.2e-11 42.8 1.2 0.00023 21.5 0.3 3.4 3 0 0 3 3 3 2 Ankyrin repeat Kunitz_BPTI PF00014.23 CDJ96172.1 - 3.3e-43 145.7 24.9 2.9e-18 65.9 6.1 4.5 3 0 0 3 3 3 3 Kunitz/Bovine pancreatic trypsin inhibitor domain EB PF01683.18 CDJ96172.1 - 1.9e-13 50.5 15.5 8.6e-10 38.8 9.0 6.3 4 2 1 5 5 5 2 EB module Sre PF03125.18 CDJ96174.1 - 8.5e-27 94.2 9.9 1.2e-26 93.7 9.9 1.2 1 0 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor 7TM_GPCR_Srab PF10292.9 CDJ96174.1 - 1.2e-09 37.6 6.2 2.3e-08 33.4 6.2 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor Tmemb_18A PF09771.9 CDJ96174.1 - 0.12 12.8 2.3 0.16 12.4 0.3 2.1 2 1 0 2 2 2 0 Transmembrane protein 188 DUF1616 PF07760.11 CDJ96174.1 - 0.24 10.8 4.6 0.35 10.2 4.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1616) SieB PF14163.6 CDJ96174.1 - 0.47 9.9 4.2 2.9 7.4 1.7 2.7 2 1 0 2 2 2 0 Super-infection exclusion protein B Oxidored_q3 PF00499.20 CDJ96174.1 - 1.9 8.2 12.6 6.3 6.5 12.6 1.8 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 SNF PF00209.18 CDJ96175.1 - 1.4e-58 198.9 9.8 1.6e-58 198.7 9.8 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Brr6_like_C_C PF10104.9 CDJ96175.1 - 0.0025 17.6 0.2 0.0039 17.0 0.2 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain BTB PF00651.31 CDJ96177.1 - 0.011 15.9 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain TPR_MLP1_2 PF07926.12 CDJ96178.1 - 0.013 15.6 9.3 0.013 15.6 9.3 6.3 3 2 3 6 6 6 0 TPR/MLP1/MLP2-like protein SOR PF07682.11 CDJ96178.1 - 0.064 12.1 0.3 0.1 11.5 0.3 1.3 1 0 0 1 1 1 0 Sulphur oxygenase reductase DUF1129 PF06570.11 CDJ96178.1 - 0.64 9.5 5.3 0.44 10.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) HALZ PF02183.18 CDJ96178.1 - 0.76 10.1 23.0 0.44 10.8 0.2 5.9 6 1 0 6 6 6 0 Homeobox associated leucine zipper Scaffolding_pro PF11418.8 CDJ96178.1 - 9.7 6.8 11.1 0.58 10.8 2.8 3.1 2 2 2 4 4 4 0 Phi29 scaffolding protein DUF2254 PF10011.9 CDJ96180.1 - 0.43 9.3 2.1 0.25 10.1 0.2 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) COQ7 PF03232.13 CDJ96180.1 - 1.3 8.7 6.5 0.3 10.9 0.3 2.9 2 1 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 SPRY PF00622.28 CDJ96181.1 - 1.1e-18 67.5 0.0 2e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.6 CDJ96181.1 - 2.1e-11 43.5 8.3 5e-11 42.3 8.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDJ96181.1 - 2.4e-05 24.1 9.5 6.5e-05 22.7 9.5 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CDJ96181.1 - 3.9 7.5 10.1 10 6.2 10.1 1.8 1 0 0 1 1 1 0 zinc-RING finger domain RtcB PF01139.17 CDJ96182.1 - 1.8e-148 495.2 0.0 2e-148 495.0 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB GTP1_OBG PF01018.22 CDJ96183.1 - 1.8e-42 144.6 6.4 2.3e-42 144.2 6.4 1.1 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 CDJ96183.1 - 2.2e-24 85.7 0.0 3.1e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ96183.1 - 1.1e-08 34.8 0.0 1.9e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CDJ96183.1 - 0.0022 17.9 0.0 0.058 13.3 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 CDJ96183.1 - 0.0048 16.9 0.0 0.0086 16.1 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Gtr1_RagA PF04670.12 CDJ96183.1 - 0.049 13.0 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Dynamin_N PF00350.23 CDJ96183.1 - 0.19 11.8 0.0 8.5 6.4 0.0 2.2 1 1 1 2 2 2 0 Dynamin family UPF0561 PF10573.9 CDJ96184.1 - 2e-09 37.6 1.4 4.9e-09 36.4 1.0 1.8 1 1 1 2 2 2 1 Uncharacterised protein family UPF0561 Asp PF00026.23 CDJ96187.1 - 6.9e-84 282.0 3.5 1.1e-83 281.2 3.5 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ96187.1 - 6.8e-17 62.3 2.4 1.2e-16 61.4 2.4 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CDJ96187.1 - 0.029 15.0 0.5 5.1 7.8 0.0 3.4 3 0 0 3 3 3 0 Aspartyl protease RVT_1 PF00078.27 CDJ96189.1 - 6.6e-08 32.3 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp PF00026.23 CDJ96190.1 - 1.1e-66 225.4 0.1 1.6e-66 224.9 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ96190.1 - 3.9e-14 53.3 0.2 7.1e-14 52.4 0.2 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.12 CDJ96190.1 - 0.00057 19.7 0.1 0.00098 18.9 0.1 1.4 1 0 0 1 1 1 1 A1 Propeptide Asp PF00026.23 CDJ96191.1 - 1.7e-65 221.6 0.0 2.1e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ96191.1 - 4.3e-09 36.9 0.0 7.4e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal HlyE PF06109.13 CDJ96192.1 - 0.04 13.2 0.2 0.046 13.0 0.2 1.0 1 0 0 1 1 1 0 Haemolysin E (HlyE) Asp PF00026.23 CDJ96193.1 - 2.8e-39 135.4 0.0 3.1e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Ferritin PF00210.24 CDJ96194.1 - 0.0072 16.3 0.1 0.012 15.6 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain DOCK-C2 PF14429.6 CDJ96196.1 - 2.3e-34 118.9 0.0 2.8e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DOCK_N PF16172.5 CDJ96197.1 - 0.0023 16.9 0.0 0.0041 16.1 0.0 1.4 1 1 0 1 1 1 1 DOCK N-terminus AATF-Che1 PF13339.6 CDJ96197.1 - 0.015 16.0 0.1 11 6.7 0.0 3.2 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor DUF4238 PF14022.6 CDJ96198.1 - 0.0043 16.6 0.3 0.0095 15.5 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4238) 7TM_GPCR_Srv PF10323.9 CDJ96200.1 - 3.4e-12 46.3 4.4 5.2e-12 45.7 4.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 CDJ96200.1 - 4.9e-11 42.8 5.1 6.8e-11 42.3 5.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Srg PF02118.21 CDJ96200.1 - 8.3e-08 32.2 3.1 1.2e-07 31.7 3.1 1.2 1 0 0 1 1 1 1 Srg family chemoreceptor 7tm_1 PF00001.21 CDJ96200.1 - 1.3e-06 27.9 0.0 5.4e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Pam17 PF08566.10 CDJ96200.1 - 0.019 14.8 0.1 1.5 8.6 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 DUF2681 PF10883.8 CDJ96200.1 - 0.035 14.5 0.9 0.1 13.0 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) 7TM_GPCR_Srv PF10323.9 CDJ96201.1 - 0.047 13.0 2.8 0.054 12.8 2.8 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv SH3_9 PF14604.6 CDJ96202.1 - 8.4e-28 96.0 0.1 1.5e-12 47.2 0.0 2.2 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 CDJ96202.1 - 9.3e-25 86.0 0.0 1.4e-14 53.4 0.0 2.1 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 CDJ96202.1 - 5e-19 67.7 0.1 2.1e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 Variant SH3 domain SH3_16 PF18348.1 CDJ96202.1 - 0.053 13.3 0.4 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain RRM_1 PF00076.22 CDJ96203.1 - 5.1e-36 122.3 0.0 1.4e-12 47.2 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ96203.1 - 0.00039 20.2 0.0 0.007 16.2 0.0 2.5 3 0 0 3 3 3 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 CDJ96203.1 - 0.0085 16.1 0.1 0.38 10.9 0.0 3.1 3 1 0 3 3 3 1 Limkain b1 RAM PF15320.6 CDJ96204.1 - 6e-06 26.8 21.2 5.3e-05 23.7 21.2 2.0 1 1 0 1 1 1 1 mRNA cap methylation, RNMT-activating mini protein VWA_2 PF13519.6 CDJ96205.1 - 3.9e-21 75.7 0.0 1e-20 74.3 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Ribosomal_L9_N PF01281.19 CDJ96205.1 - 5.2e-13 48.3 0.0 1e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ssl1 PF04056.14 CDJ96205.1 - 1.3e-09 38.2 0.7 2.6e-09 37.2 0.3 1.7 2 0 0 2 2 2 1 Ssl1-like UIM PF02809.20 CDJ96205.1 - 1.6e-07 30.7 7.6 0.00072 19.3 1.5 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif Methyltransf_33 PF10017.9 CDJ96205.1 - 0.025 13.7 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent RAP80_UIM PF18282.1 CDJ96205.1 - 2.2 8.1 6.5 0.85 9.4 1.3 2.4 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif DUF3597 PF12200.8 CDJ96205.1 - 2.2 8.8 8.9 0.55 10.8 3.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3597) Aminotran_5 PF00266.19 CDJ96206.1 - 4e-87 292.6 0.0 6.2e-87 291.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Pkinase PF00069.25 CDJ96206.1 - 1.3e-67 227.9 0.3 2.2e-67 227.2 0.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ96206.1 - 1.3e-20 73.8 0.0 2.1e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ96206.1 - 1.8e-08 34.6 0.1 7.6e-06 26.0 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Beta_elim_lyase PF01212.21 CDJ96206.1 - 9.7e-08 31.6 0.0 1.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CDJ96206.1 - 0.0012 18.2 0.2 0.0021 17.4 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pkinase_fungal PF17667.1 CDJ96206.1 - 0.008 15.0 0.4 0.026 13.3 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Pyridoxal_deC PF00282.19 CDJ96206.1 - 0.012 14.4 0.0 0.023 13.4 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Kdo PF06293.14 CDJ96206.1 - 0.031 13.6 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CDJ96206.1 - 0.053 13.1 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 CDJ96206.1 - 0.062 12.9 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 RIO1 family ABC1 PF03109.16 CDJ96206.1 - 0.15 12.2 0.1 0.34 11.1 0.1 1.5 1 0 0 1 1 1 0 ABC1 family DUF4457 PF14652.6 CDJ96207.1 - 3.1e-107 358.6 0.0 2.7e-74 250.4 0.0 4.0 1 1 2 3 3 3 3 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 CDJ96207.1 - 1.6e-05 24.9 0.0 0.36 10.8 0.0 3.9 4 0 0 4 4 4 3 Sad1 / UNC-like C-terminal XRCC1_N PF01834.16 CDJ96207.1 - 0.018 15.0 0.1 5.1 7.1 0.1 2.8 3 0 0 3 3 3 0 XRCC1 N terminal domain Pkinase PF00069.25 CDJ96209.1 - 0.00049 19.6 0.0 0.0008 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ96209.1 - 0.0026 17.1 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Snf7 PF03357.21 CDJ96210.1 - 1.8e-43 148.1 29.5 2.6e-43 147.6 26.8 1.9 2 0 0 2 2 2 1 Snf7 Robl_LC7 PF03259.17 CDJ96210.1 - 0.02 14.7 0.2 0.12 12.1 0.1 2.1 2 0 0 2 2 2 0 Roadblock/LC7 domain YlqD PF11068.8 CDJ96210.1 - 0.76 10.1 20.3 0.7 10.3 10.6 2.5 1 1 1 2 2 2 0 YlqD protein DUF4845 PF16137.5 CDJ96210.1 - 7.2 7.5 11.7 9 7.2 4.2 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4845) Histone_HNS PF00816.21 CDJ96210.1 - 7.9 7.4 9.0 4.7 8.1 5.1 2.5 1 1 2 3 3 3 0 H-NS histone family CRR7 PF12095.8 CDJ96212.1 - 0.0094 16.4 0.4 7.3 7.1 0.0 2.5 2 0 0 2 2 2 2 Protein CHLORORESPIRATORY REDUCTION 7 TPR_MalT PF17874.1 CDJ96212.1 - 0.013 14.9 0.0 4.7 6.5 0.0 2.1 2 0 0 2 2 2 0 MalT-like TPR region VGPC1_C PF16799.5 CDJ96212.1 - 0.088 12.8 0.7 17 5.4 0.0 2.4 2 0 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 LKAAEAR PF15478.6 CDJ96212.1 - 0.17 12.2 0.0 24 5.2 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function with LKAAEAR motif WH2 PF02205.20 CDJ96213.1 - 2.9e-11 42.8 0.2 1.6e-05 24.6 0.1 2.5 2 0 0 2 2 2 2 WH2 motif Anillin PF08174.11 CDJ96216.1 - 1.5e-07 31.9 0.0 1.7e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Cell division protein anillin Enolase_C PF00113.22 CDJ96217.1 - 3.5e-155 515.6 0.0 4.6e-155 515.2 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CDJ96217.1 - 4.2e-59 198.4 0.1 7e-59 197.7 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CDJ96217.1 - 5.5e-06 26.1 0.0 9.1e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 CDJ96217.1 - 2.9e-05 23.3 0.5 0.00011 21.4 0.1 2.0 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Ribosomal_L50 PF10501.9 CDJ96218.1 - 9.1e-13 48.3 0.3 1.7e-12 47.4 0.3 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S Collagen PF01391.18 CDJ96219.1 - 4.8e-22 77.5 106.2 3.6e-05 23.4 6.9 4.1 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ96219.1 - 2.9e-16 59.2 1.5 3.7e-16 58.9 1.5 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ96220.1 - 8.9e-20 70.2 106.8 3.3e-07 29.9 38.9 5.1 3 1 1 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ96220.1 - 3.1e-16 59.1 1.5 4e-16 58.8 1.5 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain DUF4723 PF15851.5 CDJ96221.1 - 1.5 9.0 11.3 0.92 9.7 3.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4723) Imm5 PF14423.6 CDJ96223.1 - 0.056 13.7 0.3 0.088 13.0 0.3 1.2 1 0 0 1 1 1 0 Immunity protein Imm5 DUF1810 PF08837.11 CDJ96223.1 - 0.058 13.2 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1810) FoP_duplication PF13865.6 CDJ96225.1 - 0.00018 22.0 0.1 0.00018 22.0 0.1 2.0 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Pkinase PF00069.25 CDJ96227.1 - 2.9e-22 79.3 0.0 3.6e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ96227.1 - 4.7e-11 42.5 0.0 6.1e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ96227.1 - 0.15 12.0 0.0 0.49 10.3 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family PspB PF06667.12 CDJ96228.1 - 0.037 14.1 0.2 0.049 13.7 0.2 1.2 1 0 0 1 1 1 0 Phage shock protein B Na_K-ATPase PF00287.18 CDJ96228.1 - 0.16 11.1 1.2 0.2 10.8 1.0 1.2 1 1 0 1 1 1 0 Sodium / potassium ATPase beta chain CHDCT2 PF08074.11 CDJ96229.1 - 4.1e-84 281.0 1.5 4.1e-84 281.0 1.5 2.0 2 0 0 2 2 1 1 CHDCT2 (NUC038) domain SNF2_N PF00176.23 CDJ96229.1 - 2.5e-59 200.8 0.0 5e-59 199.8 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1086 PF06461.11 CDJ96229.1 - 6e-53 178.4 0.0 1.5e-52 177.1 0.0 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) DUF1087 PF06465.13 CDJ96229.1 - 4.4e-27 93.9 9.6 3.2e-26 91.1 9.6 2.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) PHD PF00628.29 CDJ96229.1 - 1.7e-21 75.8 25.7 2.3e-11 43.4 8.0 2.5 2 0 0 2 2 2 2 PHD-finger Helicase_C PF00271.31 CDJ96229.1 - 9e-21 74.3 0.0 2.2e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CHDNT PF08073.12 CDJ96229.1 - 4.3e-20 71.4 0.1 1.7e-19 69.5 0.1 2.1 1 0 0 1 1 1 1 CHDNT (NUC034) domain Chromo PF00385.24 CDJ96229.1 - 9.8e-15 54.2 9.1 4.5e-09 36.1 2.4 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 CDJ96229.1 - 2e-09 37.7 0.2 1.9e-08 34.5 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit PHD_2 PF13831.6 CDJ96229.1 - 0.00015 21.2 12.9 0.005 16.4 2.5 2.6 2 0 0 2 2 2 2 PHD-finger AAA_22 PF13401.6 CDJ96229.1 - 0.032 14.5 0.1 0.16 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain zf-HC5HC2H_2 PF13832.6 CDJ96229.1 - 0.043 14.0 12.6 1.2 9.3 0.9 2.5 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-PHD-like PF15446.6 CDJ96229.1 - 0.94 9.1 11.7 2.9 7.5 1.8 3.2 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RanBP PF00641.18 CDJ96229.1 - 1.2 8.5 5.5 2.5 7.5 0.7 2.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Elong_Iki1 PF10483.9 CDJ96230.1 - 0.08 12.4 0.1 0.72 9.3 0.1 2.0 1 1 1 2 2 2 0 Elongator subunit Iki1 ASC PF00858.24 CDJ96230.1 - 0.13 11.2 1.0 0.29 10.1 1.0 1.6 1 1 1 2 2 2 0 Amiloride-sensitive sodium channel NAD_binding_3 PF03447.16 CDJ96230.1 - 0.18 12.5 0.0 0.3 11.7 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DEAD PF00270.29 CDJ96231.1 - 3.4e-45 154.0 0.0 6.7e-45 153.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ96231.1 - 3.7e-27 94.9 1.6 1.1e-26 93.4 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ96231.1 - 1.2e-05 25.4 0.0 2.5e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 CDJ96231.1 - 0.058 13.1 0.0 0.31 10.7 0.0 2.0 1 1 1 2 2 2 0 SWI2/SNF2 ATPase Phage_integrase PF00589.22 CDJ96231.1 - 0.07 12.9 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Phage integrase family Sigma70_ner PF04546.13 CDJ96231.1 - 0.42 10.5 7.9 0.15 11.9 2.1 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region Prefoldin_2 PF01920.20 CDJ96232.1 - 2.1e-20 72.7 4.7 2.1e-20 72.7 4.7 1.8 1 1 1 2 2 2 1 Prefoldin subunit KELK PF15796.5 CDJ96232.1 - 0.012 16.1 11.2 0.024 15.1 4.2 2.2 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Prefoldin PF02996.17 CDJ96232.1 - 0.016 15.1 7.7 0.11 12.4 1.1 2.9 2 1 1 3 3 3 0 Prefoldin subunit DUF3014 PF11219.8 CDJ96232.1 - 0.03 14.6 0.5 0.18 12.0 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3014) Nsp1_C PF05064.13 CDJ96232.1 - 0.7 9.7 10.5 1.2 9.0 5.6 2.3 2 1 0 2 2 2 0 Nsp1-like C-terminal region TLE_N PF03920.15 CDJ96232.1 - 0.86 9.7 8.1 0.15 12.1 3.8 1.8 1 1 1 2 2 2 0 Groucho/TLE N-terminal Q-rich domain Aminotran_5 PF00266.19 CDJ96234.1 - 1e-51 176.1 0.0 1.2e-51 175.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Fib_alpha PF08702.10 CDJ96234.1 - 0.054 13.7 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Calici_coat_C PF08435.11 CDJ96234.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal BPL_LplA_LipB PF03099.19 CDJ96235.1 - 4e-13 49.4 0.0 2.2e-12 47.0 0.0 2.0 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family BPL_N PF09825.9 CDJ96235.1 - 0.054 12.6 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal BPL_C PF02237.17 CDJ96235.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain RL PF17797.1 CDJ96235.1 - 0.093 12.7 0.1 0.28 11.2 0.1 1.8 1 0 0 1 1 1 0 RL domain SAC3_GANP PF03399.16 CDJ96236.1 - 1e-30 107.2 3.1 2.5e-29 102.6 3.1 2.3 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 CDJ96236.1 - 4e-08 33.3 0.0 1.2e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family HTH_36 PF13730.6 CDJ96236.1 - 0.15 12.0 0.0 18 5.4 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Nop53 PF07767.11 CDJ96236.1 - 1.8 7.8 28.1 0.24 10.7 19.4 2.4 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) SR-25 PF10500.9 CDJ96236.1 - 2.3 7.8 32.4 0.23 11.1 26.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein KH_1 PF00013.29 CDJ96237.1 - 4.3e-33 112.9 7.3 1.2e-16 60.3 0.3 2.3 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 CDJ96237.1 - 2.1e-08 33.8 2.5 0.0021 17.8 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 CDJ96237.1 - 0.00063 19.8 2.6 0.53 10.4 0.6 2.3 2 0 0 2 2 2 2 NusA-like KH domain KH_4 PF13083.6 CDJ96237.1 - 0.00081 19.2 1.5 0.14 12.1 0.9 2.3 2 0 0 2 2 2 2 KH domain Pkinase PF00069.25 CDJ96238.1 - 3.4e-44 151.2 0.0 4.4e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ96238.1 - 1.1e-26 93.6 0.0 1.4e-26 93.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ96238.1 - 4.7e-10 39.3 0.0 5.3e-08 32.5 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CDJ96238.1 - 0.0002 21.4 0.1 0.00049 20.1 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ96238.1 - 0.0012 17.8 0.1 0.0021 16.9 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase DUF1232 PF06803.12 CDJ96238.1 - 0.006 16.3 0.4 0.025 14.4 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1232) Kdo PF06293.14 CDJ96238.1 - 0.015 14.7 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDJ96238.1 - 0.045 13.4 0.1 0.094 12.3 0.1 1.6 1 1 0 1 1 1 0 RIO1 family Glyco_transf_25 PF01755.17 CDJ96239.1 - 1.1e-27 97.2 0.0 8.5e-27 94.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Cullin PF00888.22 CDJ96240.1 - 1.1e-179 599.1 12.3 1.1e-179 599.1 12.3 1.5 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 CDJ96240.1 - 1.6e-27 95.3 4.3 5.3e-27 93.6 4.3 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain FAM86 PF14904.6 CDJ96240.1 - 0.0078 16.3 2.6 0.082 13.0 0.2 2.8 2 0 0 2 2 2 1 Family of unknown function Penicillinase_R PF03965.16 CDJ96240.1 - 0.027 14.8 3.6 0.82 10.0 0.1 3.5 3 0 0 3 3 3 0 Penicillinase repressor Phage_TAC_12 PF12363.8 CDJ96240.1 - 0.041 14.3 1.7 0.18 12.3 0.1 2.8 3 0 0 3 3 3 0 Phage tail assembly chaperone protein, TAC DUF1759 PF03564.15 CDJ96240.1 - 0.063 13.2 0.7 0.25 11.3 0.7 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Stork_head PF10264.9 CDJ96240.1 - 0.14 12.3 0.3 0.91 9.7 0.3 2.4 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain Patched PF02460.18 CDJ96241.1 - 5.6e-96 322.4 14.5 1.3e-95 321.2 14.5 1.5 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 CDJ96241.1 - 1.9e-07 31.0 0.1 1.9e-07 31.0 0.1 3.1 3 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation SecD_SecF PF02355.16 CDJ96241.1 - 0.0067 15.8 20.7 0.016 14.6 7.1 3.4 3 0 0 3 3 3 2 Protein export membrane protein Patched PF02460.18 CDJ96242.1 - 6.9e-22 77.4 1.0 1.1e-14 53.5 1.5 2.0 1 1 1 2 2 2 2 Patched family Sterol-sensing PF12349.8 CDJ96242.1 - 1.8e-10 40.9 0.7 3.2e-10 40.0 0.7 1.3 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation nsp9 PF08710.10 CDJ96242.1 - 0.066 13.6 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 nsp9 replicase ABC2_membrane_3 PF12698.7 CDJ96243.1 - 3e-32 112.1 14.8 3e-32 112.1 14.8 2.2 3 0 0 3 3 3 1 ABC-2 family transporter protein ABC_tran PF00005.27 CDJ96243.1 - 3e-19 69.9 0.0 5e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CDJ96243.1 - 1e-11 45.2 0.2 9e-07 29.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CDJ96243.1 - 0.019 15.5 0.1 0.036 14.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain Tetraspanin PF00335.20 CDJ96244.1 - 6.4e-31 107.8 3.2 8.1e-31 107.5 3.2 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF2650 PF10853.8 CDJ96244.1 - 0.53 10.0 6.2 1.7 8.4 0.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2650) Ephrin PF00812.17 CDJ96245.1 - 3e-37 127.7 0.0 4.8e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 Ephrin Ephrin PF00812.17 CDJ96246.1 - 3.8e-08 33.4 0.0 6.4e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Ephrin Sulfate_transp PF00916.20 CDJ96247.1 - 8.7e-103 344.0 21.5 1.4e-102 343.3 21.5 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CDJ96247.1 - 1.8e-23 82.4 0.0 3.1e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 STAS domain LapA_dom PF06305.11 CDJ96247.1 - 4 7.3 6.0 27 4.7 0.1 3.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain FSAP_sig_propep PF03032.15 CDJ96248.1 - 0.008 16.2 0.2 0.012 15.6 0.2 1.2 1 0 0 1 1 1 1 Frog skin active peptide family signal and propeptide Sec10 PF07393.11 CDJ96249.1 - 9.2e-135 450.8 15.0 9.6e-132 440.8 15.0 3.0 1 1 0 1 1 1 1 Exocyst complex component Sec10 TPR_1 PF00515.28 CDJ96249.1 - 1.1e-18 66.2 3.2 4.6e-07 29.4 0.1 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ96249.1 - 1.7e-13 49.6 3.1 0.002 18.1 0.1 4.3 2 1 1 3 3 3 3 Tetratricopeptide repeat RPAP3_C PF13877.6 CDJ96249.1 - 1e-11 45.2 0.2 2.2e-10 40.9 0.0 3.2 3 0 0 3 3 2 1 Potential Monad-binding region of RPAP3 TPR_9 PF13371.6 CDJ96249.1 - 9.7e-09 35.3 1.1 3e-08 33.7 1.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ96249.1 - 6e-07 29.2 0.6 0.019 15.2 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ96249.1 - 3.6e-06 26.5 0.2 0.0088 15.7 0.0 2.9 3 0 0 3 3 2 2 TPR repeat TPR_19 PF14559.6 CDJ96249.1 - 2.7e-05 24.6 3.7 0.16 12.5 0.0 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ96249.1 - 4.4e-05 23.7 1.3 0.042 14.1 0.1 3.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ96249.1 - 0.00047 20.3 1.9 0.017 15.5 0.1 3.7 3 1 0 3 3 2 1 Tetratricopeptide repeat V_ATPase_I PF01496.19 CDJ96249.1 - 0.00056 18.0 2.4 0.00089 17.3 2.4 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family TPR_14 PF13428.6 CDJ96249.1 - 0.0018 18.9 1.6 0.96 10.4 0.3 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TMF_TATA_bd PF12325.8 CDJ96249.1 - 0.0037 17.5 2.2 0.021 15.0 2.2 2.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 CDJ96249.1 - 0.0047 17.0 2.2 0.0047 17.0 2.2 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1664) TPR_16 PF13432.6 CDJ96249.1 - 0.0052 17.4 1.2 0.02 15.6 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ96249.1 - 0.018 15.7 4.4 2.5 8.9 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ96249.1 - 0.019 15.0 0.4 0.78 9.9 0.0 3.5 2 1 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ96249.1 - 0.031 14.5 5.5 0.15 12.3 0.1 4.0 4 1 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 AsnC_trans_reg2 PF17805.1 CDJ96249.1 - 0.049 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AsnC-like ligand binding domain IFT57 PF10498.9 CDJ96249.1 - 0.053 12.5 6.4 0.08 11.9 2.1 2.3 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 JAKMIP_CC3 PF16034.5 CDJ96249.1 - 0.055 13.4 3.4 0.17 11.8 3.4 1.8 1 0 0 1 1 1 0 JAKMIP CC3 domain THOC7 PF05615.13 CDJ96249.1 - 0.078 13.3 1.2 0.33 11.2 1.2 2.1 1 0 0 1 1 1 0 Tho complex subunit 7 DUF4200 PF13863.6 CDJ96249.1 - 0.33 11.4 10.4 0.05 14.0 5.3 2.3 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) Lectin_N PF03954.14 CDJ96249.1 - 0.46 10.2 4.1 13 5.5 1.2 2.9 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain CLZ PF16526.5 CDJ96249.1 - 0.54 10.7 6.3 12 6.3 0.2 4.1 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels KAP_NTPase PF07693.14 CDJ96249.1 - 2.6 7.2 6.3 0.38 9.9 1.1 2.2 2 0 0 2 2 2 0 KAP family P-loop domain Cep57_CLD_2 PF14197.6 CDJ96249.1 - 2.8 8.1 6.9 1.7 8.8 1.2 3.1 3 0 0 3 3 2 0 Centrosome localisation domain of PPC89 ZapB PF06005.12 CDJ96249.1 - 5 7.6 6.7 20 5.7 0.8 3.9 3 1 1 4 4 3 0 Cell division protein ZapB Swi5 PF07061.11 CDJ96249.1 - 5.6 7.1 5.9 28 4.9 0.5 3.5 3 0 0 3 3 2 0 Swi5 TPR_MLP1_2 PF07926.12 CDJ96249.1 - 8.8 6.4 12.9 0.12 12.4 4.3 2.4 3 0 0 3 3 1 0 TPR/MLP1/MLP2-like protein TMEM65 PF10507.9 CDJ96250.1 - 3.6e-44 149.2 1.7 2.6e-43 146.4 1.5 2.1 2 0 0 2 2 2 1 Transmembrane protein 65 DUF2465 PF10239.9 CDJ96251.1 - 1.5e-58 198.5 0.5 2.8e-58 197.7 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) G_path_suppress PF15991.5 CDJ96251.1 - 0.24 11.5 21.5 0.35 11.0 21.5 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor TFIIA PF03153.13 CDJ96251.1 - 3.7 7.4 17.8 4.9 7.0 17.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit KTI12 PF08433.10 CDJ96252.1 - 2.2e-11 43.7 0.0 3.4e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 CDJ96252.1 - 2.7e-09 37.3 0.0 4.7e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CDJ96252.1 - 6.7e-09 36.4 0.1 3.2e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ96252.1 - 0.00022 21.6 0.0 0.0088 16.4 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 CDJ96252.1 - 0.0007 19.6 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CDJ96252.1 - 0.023 15.1 0.4 0.13 12.7 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CDJ96252.1 - 0.029 14.7 0.1 0.29 11.4 0.1 2.6 2 2 0 2 2 2 0 AAA domain CPT PF07931.12 CDJ96252.1 - 0.031 14.1 0.3 1.5 8.6 0.3 2.4 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 CDJ96252.1 - 0.063 12.6 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 CDJ96252.1 - 0.093 12.8 0.0 0.23 11.5 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Arf PF00025.21 CDJ96252.1 - 0.15 11.5 0.1 1.6 8.1 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family PduV-EutP PF10662.9 CDJ96252.1 - 0.22 11.3 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF1943 PF09172.11 CDJ96253.1 - 0.03 13.6 0.1 0.067 12.4 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) DUF1180 PF06679.12 CDJ96254.1 - 0.015 15.8 0.2 0.019 15.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Spt20 PF12090.8 CDJ96254.1 - 0.024 14.2 2.6 0.027 14.1 2.6 1.1 1 0 0 1 1 1 0 Spt20 family Prominin PF05478.11 CDJ96254.1 - 0.035 12.1 1.0 0.049 11.6 1.0 1.2 1 0 0 1 1 1 0 Prominin PHC2_SAM_assoc PF16616.5 CDJ96254.1 - 0.12 13.1 5.3 0.16 12.8 5.3 1.1 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Connexin PF00029.19 CDJ96254.1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Connexin Orf78 PF06024.12 CDJ96254.1 - 0.7 10.2 2.2 1.8 8.9 2.2 1.7 1 1 0 1 1 1 0 Orf78 (ac78) Alpha_kinase PF02816.18 CDJ96256.1 - 0.015 15.4 0.0 0.019 15.1 0.0 1.1 1 0 0 1 1 1 0 Alpha-kinase family TRAP_beta PF05753.14 CDJ96257.1 - 7.1e-39 133.0 0.0 7.8e-39 132.9 0.0 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) RVT_1 PF00078.27 CDJ96258.1 - 2.7e-29 102.3 0.0 3.1e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pyr_excise PF03013.14 CDJ96258.1 - 0.16 11.9 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase ANF_receptor PF01094.28 CDJ96259.1 - 8.7e-08 31.6 0.0 1.4e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 CDJ96259.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Spt20 PF12090.8 CDJ96260.1 - 0.083 12.5 5.1 0.15 11.6 5.1 1.4 1 0 0 1 1 1 0 Spt20 family Conotoxin PF02950.17 CDJ96260.1 - 0.22 12.6 0.7 5.7 8.0 0.0 2.8 2 0 0 2 2 2 0 Conotoxin DDE_Tnp_IS1595 PF12762.7 CDJ96262.1 - 2.3e-16 60.2 0.0 3.2e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS66 PF03050.14 CDJ96262.1 - 7.6e-07 28.9 0.2 1e-06 28.5 0.2 1.1 1 0 0 1 1 1 1 Transposase IS66 family DUF4286 PF14114.6 CDJ96262.1 - 0.095 13.2 0.2 0.17 12.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) Ndc1_Nup PF09531.10 CDJ96263.1 - 3.2 6.3 5.6 3.4 6.2 5.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LapA_dom PF06305.11 CDJ96264.1 - 0.00034 20.4 1.0 0.00043 20.1 1.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide assembly protein A domain MAP17 PF15807.5 CDJ96264.1 - 0.0004 20.6 0.1 0.00048 20.3 0.1 1.2 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Myc_target_1 PF15179.6 CDJ96264.1 - 0.0058 16.6 0.0 0.0058 16.6 0.0 1.0 1 0 0 1 1 1 1 Myc target protein 1 FAM176 PF14851.6 CDJ96264.1 - 0.0062 16.2 0.0 0.0063 16.2 0.0 1.0 1 0 0 1 1 1 1 FAM176 family EMC3_TMCO1 PF01956.16 CDJ96264.1 - 0.0095 15.7 0.3 0.01 15.6 0.3 1.0 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like TssO PF17561.2 CDJ96264.1 - 0.011 15.8 0.2 0.013 15.6 0.2 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssO DUF4834 PF16118.5 CDJ96264.1 - 0.019 15.9 0.1 0.025 15.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Zip PF02535.22 CDJ96264.1 - 0.06 12.6 0.1 0.062 12.5 0.1 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter TerC PF03741.16 CDJ96264.1 - 0.064 12.9 0.1 0.066 12.9 0.1 1.1 1 0 0 1 1 1 0 Integral membrane protein TerC family Connexin PF00029.19 CDJ96264.1 - 0.089 12.5 0.1 0.1 12.4 0.1 1.1 1 0 0 1 1 1 0 Connexin OATP PF03137.20 CDJ96264.1 - 0.09 11.0 0.5 0.1 10.8 0.5 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MscS_TM PF12794.7 CDJ96264.1 - 0.13 11.1 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Ac76 PF05814.11 CDJ96264.1 - 1.8 8.6 5.6 3.3 7.8 5.6 1.6 1 1 0 1 1 1 0 Orf76 (Ac76) OAD_gamma PF04277.13 CDJ96264.1 - 7.3 7.3 6.8 20 5.9 6.8 1.8 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain RRM_1 PF00076.22 CDJ96265.1 - 0.007 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) fn3 PF00041.21 CDJ96266.1 - 8.8e-18 64.4 4.3 1.8e-12 47.5 0.1 3.7 3 1 0 3 3 3 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CDJ96266.1 - 0.00019 21.9 2.1 0.11 13.1 0.0 2.5 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain TLP1_add_C PF18313.1 CDJ96266.1 - 0.074 13.0 0.3 0.22 11.5 0.1 2.0 2 0 0 2 2 2 0 Thiolase-like protein type 1 additional C-terminal domain TCTP PF00838.17 CDJ96269.1 - 6.4e-18 65.6 0.9 7.6e-18 65.4 0.9 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Y_phosphatase PF00102.27 CDJ96270.1 - 8e-57 192.5 0.2 1.5e-56 191.6 0.2 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DUF1296 PF06972.11 CDJ96270.1 - 0.1 12.8 0.1 0.24 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) DUF2779 PF11074.8 CDJ96270.1 - 0.15 12.5 0.0 0.34 11.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function(DUF2779) CUB PF00431.20 CDJ96271.1 - 1.5e-39 134.7 3.2 1.5e-14 54.3 0.6 5.3 4 1 1 5 5 5 5 CUB domain Asp PF00026.23 CDJ96272.1 - 2.9e-28 99.2 0.0 3.3e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease VGPC1_C PF16799.5 CDJ96274.1 - 0.016 15.2 1.1 0.15 12.0 1.1 2.8 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Surfac_D-trimer PF09006.11 CDJ96274.1 - 0.018 14.9 0.9 1.2 9.1 0.1 3.7 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation DUF2730 PF10805.8 CDJ96274.1 - 0.41 10.8 0.0 0.41 10.8 0.0 8.2 6 2 5 11 11 11 0 Protein of unknown function (DUF2730) Rh5 PF18515.1 CDJ96274.1 - 6.2 6.0 11.7 7.1 5.8 2.1 3.8 4 0 0 4 4 4 0 Rh5 coiled-coil domain MobC PF05713.11 CDJ96274.1 - 6.4 7.3 7.9 58 4.3 0.3 4.8 3 0 0 3 3 3 0 Bacterial mobilisation protein (MobC) SPC22 PF04573.12 CDJ96275.1 - 2.2e-51 173.7 0.8 2.5e-51 173.6 0.8 1.0 1 0 0 1 1 1 1 Signal peptidase subunit DUF3767 PF12597.8 CDJ96275.1 - 0.005 16.6 0.0 0.0082 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) NUDIX PF00293.28 CDJ96276.1 - 1.4e-13 51.0 0.0 2e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Sec7 PF01369.20 CDJ96277.1 - 5.2e-60 202.3 0.0 1.3e-59 201.0 0.0 1.7 2 0 0 2 2 2 1 Sec7 domain bVLRF1 PF18826.1 CDJ96277.1 - 2.5e-49 167.0 0.1 1.9e-48 164.1 0.0 2.5 3 0 0 3 3 3 1 bacteroidetes VLRF1 release factor PH PF00169.29 CDJ96277.1 - 2e-17 63.6 0.4 9.2e-17 61.5 0.0 2.4 2 0 0 2 2 2 1 PH domain VATC PF18716.1 CDJ96277.1 - 1.9e-09 37.2 1.3 1.3e-07 31.4 0.5 2.7 2 0 0 2 2 2 1 Vms1-associating treble clef domain Ank_2 PF12796.7 CDJ96277.1 - 2.3e-07 31.3 0.1 2.1e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) PH_11 PF15413.6 CDJ96277.1 - 0.00034 21.0 0.5 0.002 18.5 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain Ank_5 PF13857.6 CDJ96277.1 - 0.00062 20.0 0.0 0.0018 18.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ96277.1 - 0.0016 18.8 0.0 0.0066 16.9 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeat Ank PF00023.30 CDJ96277.1 - 0.0096 16.3 0.0 0.037 14.5 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 CDJ96277.1 - 0.029 15.0 0.0 0.13 12.9 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeats (many copies) acVLRF1 PF18859.1 CDJ96277.1 - 0.069 13.4 0.6 0.18 12.1 0.1 2.0 2 0 0 2 2 1 0 Actinobacteria/chloroflexi VLRF1 release factor LYRIC PF15686.5 CDJ96277.1 - 1 8.9 16.9 0.31 10.5 12.9 2.0 2 1 0 2 2 2 0 Lysine-rich CEACAM1 co-isolated protein family Cullin PF00888.22 CDJ96278.1 - 1.7e-17 63.3 0.0 2.8e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 CDJ96278.1 - 1.6e-07 31.7 0.0 1.9e-06 28.2 0.0 2.7 3 0 0 3 3 3 1 Anaphase promoting complex (APC) subunit 2 HTH_23 PF13384.6 CDJ96278.1 - 0.027 14.3 0.7 0.027 14.3 0.7 2.1 2 0 0 2 2 2 0 Homeodomain-like domain Sigma70_r4 PF04545.16 CDJ96278.1 - 0.039 13.5 2.2 0.043 13.3 0.2 2.1 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_8 PF02954.19 CDJ96278.1 - 0.13 12.1 0.1 27 4.6 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family MarR_2 PF12802.7 CDJ96278.1 - 0.14 12.1 0.0 0.49 10.3 0.0 1.9 2 0 0 2 2 2 0 MarR family Ribosomal_S25 PF03297.15 CDJ96278.1 - 0.15 12.3 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 S25 ribosomal protein Glucosamine_iso PF01182.20 CDJ96279.1 - 7.9e-22 78.2 0.0 1.2e-21 77.6 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PI_PP_I PF18363.1 CDJ96280.1 - 0.035 14.3 0.0 0.076 13.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain CortBP2 PF09727.9 CDJ96281.1 - 7e-57 192.4 21.2 7e-57 192.4 21.2 1.7 2 0 0 2 2 2 1 Cortactin-binding protein-2 DUF3564 PF12087.8 CDJ96281.1 - 0.2 11.6 1.4 2.1 8.3 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3564) ATP-synt_S1 PF05827.12 CDJ96282.1 - 1.7e-19 70.1 2.1 2.5e-19 69.6 2.1 1.4 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Amastin PF07344.11 CDJ96282.1 - 0.0028 17.5 0.1 0.0035 17.2 0.1 1.3 1 0 0 1 1 1 1 Amastin surface glycoprotein Peptidase_S9 PF00326.21 CDJ96282.1 - 0.015 14.8 0.1 0.017 14.6 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family RRM_1 PF00076.22 CDJ96283.1 - 2.9e-84 276.9 3.8 4.7e-21 74.4 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CDJ96283.1 - 4.5e-26 90.8 0.5 7.1e-25 87.0 0.6 2.4 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 CDJ96283.1 - 2.8e-10 39.8 0.8 0.07 12.7 0.0 4.4 1 1 3 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDJ96283.1 - 1.7e-09 37.5 0.5 0.0049 16.8 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CDJ96283.1 - 7.9e-06 25.9 1.5 1.8 8.8 0.1 5.1 3 2 1 4 4 4 1 RNA recognition motif RRM_3 PF08777.11 CDJ96283.1 - 0.00018 21.5 3.5 1.2 9.3 0.0 3.9 4 0 0 4 4 4 2 RNA binding motif RRM_occluded PF16842.5 CDJ96283.1 - 0.00022 21.0 0.0 0.16 11.8 0.0 3.5 3 0 0 3 3 3 1 Occluded RNA-recognition motif OB_RNB PF08206.11 CDJ96283.1 - 0.0006 19.4 0.8 7.5 6.3 0.1 3.5 3 0 0 3 3 3 2 Ribonuclease B OB domain SET_assoc PF11767.8 CDJ96283.1 - 0.028 14.1 0.2 41 3.9 0.1 4.1 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated DUF3295 PF11702.8 CDJ96283.1 - 0.15 11.4 0.4 0.28 10.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) His_Phos_2 PF00328.22 CDJ96285.1 - 2.9e-09 36.7 0.3 0.00032 20.2 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF2205 PF10224.9 CDJ96286.1 - 0.0011 18.9 2.1 0.0015 18.5 0.5 2.0 2 0 0 2 2 2 1 Short coiled-coil protein FlaC_arch PF05377.11 CDJ96286.1 - 0.092 13.2 0.5 0.21 12.0 0.5 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF3573 PF12097.8 CDJ96286.1 - 0.098 11.5 0.3 0.12 11.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DivIC PF04977.15 CDJ96286.1 - 0.15 11.9 1.9 0.23 11.3 1.5 1.5 1 1 0 1 1 1 0 Septum formation initiator Glyco_hydro_1 PF00232.18 CDJ96287.1 - 6.4e-134 446.8 0.2 7.7e-134 446.5 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 SH3_9 PF14604.6 CDJ96289.1 - 5.6e-07 29.3 0.0 1.4e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CDJ96289.1 - 0.00033 20.3 0.0 0.00083 19.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DivIVA PF05103.13 CDJ96289.1 - 0.0046 17.0 0.3 0.0088 16.1 0.3 1.4 1 0 0 1 1 1 1 DivIVA protein SH3_1 PF00018.28 CDJ96289.1 - 0.029 14.0 0.0 0.069 12.8 0.0 1.7 1 0 0 1 1 1 0 SH3 domain FAM70 PF14967.6 CDJ96290.1 - 0.15 11.5 6.0 0.16 11.4 6.0 1.1 1 0 0 1 1 1 0 FAM70 protein DUF1815 PF08844.10 CDJ96290.1 - 1.4 9.0 4.2 0.6 10.1 1.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1815) Toxin_TOLIP PF00087.21 CDJ96290.1 - 6.3 7.1 15.8 12 6.2 15.8 1.5 1 1 0 1 1 1 0 Snake toxin and toxin-like protein IMPDH PF00478.25 CDJ96291.1 - 1.1e-82 277.9 0.1 1.3e-82 277.6 0.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 CDJ96291.1 - 9.5e-05 21.6 5.1 0.00016 20.8 5.1 1.5 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Aldolase PF01081.19 CDJ96291.1 - 0.028 13.9 0.4 0.59 9.5 0.0 2.3 1 1 0 2 2 2 0 KDPG and KHG aldolase dCache_3 PF14827.6 CDJ96291.1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase Pkinase PF00069.25 CDJ96294.1 - 4.7e-66 222.9 0.0 5.6e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ96294.1 - 2.1e-30 105.9 0.0 3.4e-30 105.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ96294.1 - 0.00071 19.0 0.1 0.0013 18.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ96294.1 - 0.0013 18.7 1.0 0.011 15.7 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 CDJ96294.1 - 0.01 15.5 0.1 0.016 14.8 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 CDJ96294.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 CDJ96294.1 - 0.013 14.4 0.1 0.019 13.9 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Ion_trans_2 PF07885.16 CDJ96295.1 - 8.9e-33 112.1 18.9 6.7e-17 61.2 1.8 2.2 2 0 0 2 2 2 2 Ion channel Apolipoprotein PF01442.18 CDJ96296.1 - 0.00037 20.4 3.6 0.014 15.3 0.6 2.2 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain DUF2884 PF11101.8 CDJ96296.1 - 0.0021 17.6 1.2 0.003 17.1 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) Baculo_PEP_C PF04513.12 CDJ96296.1 - 0.0043 17.1 3.2 0.34 11.0 0.3 2.4 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus HSCB_C PF07743.13 CDJ96296.1 - 0.0062 17.0 1.8 0.2 12.1 0.1 2.4 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DUF5591 PF17884.1 CDJ96296.1 - 0.038 13.9 0.0 0.081 12.8 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5591) FUSC PF04632.12 CDJ96296.1 - 0.04 12.5 0.8 0.047 12.2 0.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 CDJ96296.1 - 0.26 11.3 2.9 1.8 8.6 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TPR_10 PF13374.6 CDJ96297.1 - 6.8e-60 197.5 14.9 1.4e-13 50.2 0.0 6.7 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ96297.1 - 9.6e-58 192.4 17.3 1e-19 70.6 0.5 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ96297.1 - 1.8e-34 115.2 13.2 3.3e-06 26.7 0.1 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ96297.1 - 1.8e-29 100.3 30.6 2.3e-07 30.3 3.3 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ96297.1 - 9.9e-23 78.4 27.7 0.00017 21.5 2.2 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ96297.1 - 8.7e-18 63.0 26.0 0.0023 18.0 1.3 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_MalT PF17874.1 CDJ96297.1 - 2e-14 53.7 4.6 3.4e-14 53.0 0.7 2.6 3 0 0 3 3 3 1 MalT-like TPR region TPR_16 PF13432.6 CDJ96297.1 - 1.9e-13 50.8 10.4 0.0013 19.3 0.1 5.6 3 2 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ96297.1 - 8.3e-12 44.9 11.0 1.1 10.3 0.0 6.5 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ96297.1 - 1.4e-11 44.7 12.2 5.2e-05 23.7 0.4 4.4 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ96297.1 - 6.9e-10 38.6 8.4 0.16 12.4 0.2 6.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 CDJ96297.1 - 3.7e-07 30.1 0.0 12 6.9 0.1 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ96297.1 - 1.7e-06 28.1 12.0 0.0092 16.2 0.3 4.3 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 CDJ96297.1 - 4.7e-06 26.5 1.7 0.014 15.6 0.0 5.1 6 0 0 6 6 5 1 PPR repeat ATG16 PF08614.11 CDJ96297.1 - 0.0018 18.6 5.8 0.0018 18.6 5.8 4.3 4 1 1 5 5 5 1 Autophagy protein 16 (ATG16) PPR_2 PF13041.6 CDJ96297.1 - 0.0084 16.3 1.7 0.92 9.8 0.0 3.3 3 0 0 3 3 2 1 PPR repeat family SHNi-TPR PF10516.9 CDJ96297.1 - 0.013 15.0 5.5 0.84 9.1 0.2 4.4 4 0 0 4 4 4 0 SHNi-TPR RPN6_N PF18055.1 CDJ96297.1 - 0.013 15.8 4.0 5.5 7.4 0.1 3.9 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_11 PF13414.6 CDJ96297.1 - 0.013 15.1 1.3 0.013 15.1 1.3 6.0 6 0 0 6 6 6 0 TPR repeat WbqC PF08889.11 CDJ96297.1 - 0.025 14.5 2.5 8 6.3 0.0 3.8 3 1 1 4 4 4 0 WbqC-like protein family TPR_3 PF07720.12 CDJ96297.1 - 0.029 14.4 16.2 0.69 10.0 0.8 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Erythro-docking PF09277.11 CDJ96297.1 - 0.072 13.0 0.3 5.3 7.0 0.0 3.2 3 0 0 3 3 3 0 Erythronolide synthase, docking MIT PF04212.18 CDJ96297.1 - 0.086 12.9 14.4 5.4 7.2 1.3 5.5 3 1 2 5 5 5 0 MIT (microtubule interacting and transport) domain L27 PF02828.16 CDJ96297.1 - 0.13 12.0 0.3 0.56 10.0 0.0 2.3 2 0 0 2 2 1 0 L27 domain RPN7 PF10602.9 CDJ96297.1 - 0.15 11.8 6.7 0.87 9.3 0.4 3.4 2 1 2 4 4 3 0 26S proteasome subunit RPN7 Clathrin PF00637.20 CDJ96297.1 - 0.16 11.8 4.7 0.29 11.0 0.4 3.1 1 1 2 3 3 3 0 Region in Clathrin and VPS Wzy_C_2 PF11846.8 CDJ96297.1 - 0.19 11.6 3.9 2.3 8.1 0.0 3.8 4 1 0 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal TSC22 PF01166.18 CDJ96297.1 - 0.31 11.4 3.2 13 6.2 0.5 2.9 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF4919 PF16266.5 CDJ96297.1 - 0.34 10.8 4.1 0.39 10.6 0.1 3.2 2 2 0 3 3 3 0 Domain of unknown function (DUF4919) JIP_LZII PF16471.5 CDJ96297.1 - 0.49 10.6 5.1 0.45 10.7 2.9 2.2 2 0 0 2 2 1 0 JNK-interacting protein leucine zipper II YfdX PF10938.8 CDJ96297.1 - 1.4 8.8 5.8 19 5.2 0.5 3.5 4 0 0 4 4 3 0 YfdX protein COG2 PF06148.11 CDJ96297.1 - 1.9 8.5 5.5 37 4.4 2.3 3.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_6 PF13174.6 CDJ96297.1 - 2.3 9.0 18.5 4 8.3 0.3 5.2 6 0 0 6 6 4 0 Tetratricopeptide repeat TMF_TATA_bd PF12325.8 CDJ96297.1 - 3.1 8.0 15.1 0.23 11.7 6.1 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF627 PF04781.12 CDJ96297.1 - 3.7 7.6 9.5 24 5.0 0.1 4.2 4 1 1 5 5 3 0 Protein of unknown function (DUF627) AATF-Che1 PF13339.6 CDJ96297.1 - 4.2 8.1 12.5 19 5.9 1.2 3.6 2 2 1 3 3 3 0 Apoptosis antagonizing transcription factor 7TMR-HDED PF07697.11 CDJ96298.1 - 0.0066 16.6 0.1 0.0081 16.3 0.1 1.3 1 0 0 1 1 1 1 7TM-HD extracellular CHCH PF06747.13 CDJ96300.1 - 1.8e-08 34.3 4.9 3e-08 33.6 4.9 1.4 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 CDJ96300.1 - 0.24 11.4 4.4 8.5 6.5 4.5 2.2 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like zf-C4 PF00105.18 CDJ96302.1 - 5.1e-20 71.7 11.5 9.2e-20 70.9 11.5 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) BLOC1_2 PF10046.9 CDJ96307.1 - 0.0082 16.4 1.2 0.02 15.2 0.6 1.9 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 PAP_central PF04928.17 CDJ96307.1 - 0.059 12.3 0.6 0.083 11.9 0.6 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain Pex24p PF06398.11 CDJ96307.1 - 0.06 12.3 3.5 0.079 11.9 3.5 1.4 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF3716 PF12511.8 CDJ96307.1 - 0.097 12.7 0.6 0.15 12.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) DUF4298 PF14131.6 CDJ96307.1 - 0.81 9.7 6.4 0.2 11.7 2.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) V_ATPase_I PF01496.19 CDJ96307.1 - 0.89 7.4 6.4 1.1 7.0 6.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PCRF PF03462.18 CDJ96307.1 - 4.6 7.1 8.3 7.6 6.4 7.8 1.6 1 1 0 1 1 1 0 PCRF domain HSP20 PF00011.21 CDJ96308.1 - 1.4e-14 54.1 0.0 1.7e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ96308.1 - 0.0001 21.8 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA RasGEF PF00617.19 CDJ96310.1 - 3.6e-25 89.2 0.7 4.9e-25 88.7 0.2 1.5 2 0 0 2 2 2 1 RasGEF domain Glycogen_syn PF05693.13 CDJ96311.1 - 0 1091.2 0.0 0 1090.9 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_4 PF13439.6 CDJ96311.1 - 2.5e-05 24.4 0.1 6.7e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 CDJ96311.1 - 5e-05 22.9 0.0 0.00017 21.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CDJ96311.1 - 0.0013 19.2 0.0 0.0062 17.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 TMEM138 PF14935.6 CDJ96312.1 - 2.5e-36 124.9 7.9 3.4e-36 124.5 7.9 1.1 1 0 0 1 1 1 1 Transmembrane protein 138 DUF2484 PF10658.9 CDJ96312.1 - 0.11 12.8 0.6 0.11 12.8 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2484) Tub PF01167.18 CDJ96313.1 - 2.4e-87 292.7 0.0 3.4e-87 292.2 0.0 1.2 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 CDJ96313.1 - 0.00022 20.9 1.4 0.0057 16.3 0.1 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF3527) GAGE PF05831.11 CDJ96313.1 - 0.0043 17.6 0.6 0.0095 16.5 0.6 1.6 1 0 0 1 1 1 1 GAGE protein Tub_N PF16322.5 CDJ96313.1 - 0.032 14.6 7.9 1.3 9.3 3.3 2.3 2 0 0 2 2 2 0 Tubby N-terminal BTB PF00651.31 CDJ96314.1 - 2.3e-10 40.7 0.0 6.3e-10 39.3 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain zf-H2C2_5 PF13909.6 CDJ96314.1 - 0.00035 20.2 4.7 0.26 11.1 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 CDJ96314.1 - 0.017 15.6 1.2 0.017 15.6 1.2 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ96314.1 - 0.098 13.5 22.1 0.31 12.0 1.1 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDJ96314.1 - 0.17 12.4 0.2 0.17 12.4 0.2 4.2 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_2 PF12756.7 CDJ96314.1 - 0.38 11.1 4.8 7 7.1 0.2 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 CDJ96314.1 - 0.51 10.7 7.0 17 5.8 4.4 3.0 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding RNA_POL_M_15KD PF02150.16 CDJ96314.1 - 1.5 8.8 6.9 4.8 7.1 0.4 2.9 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit AAR2 PF05282.11 CDJ96315.1 - 2.1e-91 307.0 0.0 2.5e-91 306.7 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein PQ-loop PF04193.14 CDJ96316.1 - 6.3e-24 83.5 17.7 5.7e-19 67.6 5.1 3.4 3 0 0 3 3 3 2 PQ loop repeat Spec3 PF15795.5 CDJ96316.1 - 0.0061 17.1 0.6 0.0061 17.1 0.6 2.4 2 0 0 2 2 2 1 Ectodermal ciliogenesis protein ATP_synt_H PF05493.13 CDJ96316.1 - 3.2 8.3 7.8 0.35 11.4 1.0 2.6 2 0 0 2 2 2 0 ATP synthase subunit H AAA PF00004.29 CDJ96317.1 - 2.1e-30 105.9 0.0 5.2e-30 104.6 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CDJ96317.1 - 5.7e-06 26.0 0.5 0.071 12.7 0.2 2.4 1 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CDJ96317.1 - 8.4e-06 26.4 0.0 2.2e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ96317.1 - 2.4e-05 24.8 0.0 3.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDJ96317.1 - 0.00015 22.1 0.3 0.00095 19.5 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CDJ96317.1 - 0.0005 19.9 0.0 0.0011 18.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CDJ96317.1 - 0.00055 19.7 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 CDJ96317.1 - 0.00074 19.5 0.0 0.0025 17.8 0.0 1.8 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 CDJ96317.1 - 0.0014 19.0 0.0 0.0046 17.3 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_5 PF07728.14 CDJ96317.1 - 0.0015 18.6 0.1 0.0082 16.2 0.0 2.3 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 CDJ96317.1 - 0.002 17.5 0.0 0.0037 16.6 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_28 PF13521.6 CDJ96317.1 - 0.0027 18.0 0.0 0.007 16.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CDJ96317.1 - 0.0034 17.4 0.0 0.0062 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ96317.1 - 0.0039 17.5 0.1 0.012 15.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDJ96317.1 - 0.0054 16.9 0.0 0.012 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CDJ96317.1 - 0.0059 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 CDJ96317.1 - 0.0062 16.3 0.2 0.035 13.8 0.0 2.3 3 0 0 3 3 3 1 IstB-like ATP binding protein NACHT PF05729.12 CDJ96317.1 - 0.01 15.8 0.2 0.033 14.1 0.2 2.0 1 1 0 1 1 1 1 NACHT domain Mg_chelatase PF01078.21 CDJ96317.1 - 0.01 15.3 0.1 0.032 13.6 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 CDJ96317.1 - 0.019 14.8 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CDJ96317.1 - 0.021 15.2 0.0 0.044 14.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CDJ96317.1 - 0.022 14.5 0.0 0.067 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF1091 PF06477.13 CDJ96317.1 - 0.032 14.7 0.0 0.068 13.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1091) Cytidylate_kin PF02224.18 CDJ96317.1 - 0.044 13.5 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase AAA_2 PF07724.14 CDJ96317.1 - 0.045 13.9 0.0 0.11 12.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 CDJ96317.1 - 0.045 13.2 0.1 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 CDJ96317.1 - 0.063 12.7 0.0 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein TIP49 PF06068.13 CDJ96317.1 - 0.091 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 CDJ96317.1 - 0.099 12.5 0.1 16 5.3 0.0 2.4 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CDJ96317.1 - 0.13 11.9 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 CDJ96317.1 - 0.14 12.6 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF815 PF05673.13 CDJ96317.1 - 0.16 11.1 0.1 1.1 8.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Sugar_tr PF00083.24 CDJ96318.1 - 1.2e-30 106.8 12.1 1.7e-30 106.3 12.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ96318.1 - 5.6e-26 91.3 16.6 5.6e-26 91.3 16.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Transposase_1 PF01359.18 CDJ96318.1 - 0.0022 17.8 0.4 0.024 14.4 0.0 2.4 2 0 0 2 2 2 1 Transposase (partial DDE domain) Folate_carrier PF01770.18 CDJ96318.1 - 0.0037 16.1 0.7 0.01 14.6 0.3 1.7 1 1 0 1 1 1 1 Reduced folate carrier DUF872 PF05915.12 CDJ96318.1 - 0.57 10.4 2.5 1.3 9.2 0.7 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Gram_pos_anchor PF00746.21 CDJ96318.1 - 0.73 9.8 3.6 13 5.9 0.4 3.0 2 0 0 2 2 2 0 LPXTG cell wall anchor motif CBFD_NFYB_HMF PF00808.23 CDJ96319.1 - 1.3e-14 54.2 0.2 1.3e-14 54.2 0.2 2.4 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDJ96319.1 - 6.8e-11 42.6 0.3 1.7e-10 41.4 0.3 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF3853 PF12964.7 CDJ96319.1 - 0.13 12.4 0.1 0.41 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3853) DUF4796 PF16044.5 CDJ96320.1 - 8.9e-22 77.6 0.0 1.1e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4796) RRM_7 PF16367.5 CDJ96321.1 - 2.4e-34 117.3 0.3 3.3e-31 107.2 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif CEBP_ZZ PF16366.5 CDJ96321.1 - 1e-19 70.5 5.6 1e-19 70.5 5.6 2.1 2 0 0 2 2 2 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 CDJ96321.1 - 6.4e-08 32.3 0.1 0.00056 19.7 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AATF-Che1 PF13339.6 CDJ96321.1 - 4.4 8.0 6.9 0.94 10.2 2.3 2.3 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor TPP_enzyme_N PF02776.18 CDJ96322.1 - 1e-50 171.7 0.0 2e-47 161.0 0.1 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CDJ96322.1 - 3.6e-31 107.7 0.0 8e-31 106.6 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CDJ96322.1 - 3.5e-24 85.3 0.0 9.2e-24 84.0 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.16 CDJ96322.1 - 0.019 14.8 0.0 0.053 13.3 0.0 1.7 2 0 0 2 2 2 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit tRNA_synthFbeta PF17759.1 CDJ96324.1 - 2.1e-48 164.6 0.0 3.5e-48 163.9 0.0 1.4 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 CDJ96324.1 - 2.4e-35 120.6 0.4 4.3e-33 113.4 0.1 2.5 2 0 0 2 2 2 2 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 CDJ96324.1 - 2.5e-27 95.6 0.1 4.2e-27 94.9 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 CDJ96324.1 - 1.1e-19 70.5 0.1 2.6e-16 59.6 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF2740 PF10872.8 CDJ96324.1 - 0.18 11.7 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) EMC3_TMCO1 PF01956.16 CDJ96325.1 - 1.2e-38 132.5 0.0 1.6e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like CbiC PF02570.15 CDJ96325.1 - 0.03 14.0 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 Precorrin-8X methylmutase DUF3567 PF12091.8 CDJ96325.1 - 0.05 13.7 0.3 0.08 13.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) Scm3 PF10384.9 CDJ96325.1 - 0.096 12.4 1.7 0.16 11.7 0.8 1.9 2 0 0 2 2 2 0 Centromere protein Scm3 DUF3333 PF11812.8 CDJ96325.1 - 0.31 11.2 2.9 0.36 11.0 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3333) DivIC PF04977.15 CDJ96325.1 - 1.1 9.1 5.3 5.7 6.8 5.3 1.9 1 1 0 1 1 1 0 Septum formation initiator CK_II_beta PF01214.18 CDJ96326.1 - 1.1e-75 253.4 0.0 1.3e-75 253.3 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CxC5 PF18718.1 CDJ96326.1 - 0.044 13.9 0.0 0.067 13.3 0.0 1.2 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases DUF3449 PF11931.8 CDJ96327.1 - 2.9e-75 252.1 0.6 2.9e-75 252.1 0.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 CDJ96327.1 - 1.2e-25 89.8 3.8 2.7e-25 88.7 3.8 1.6 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Telomere_Sde2_2 PF13297.6 CDJ96327.1 - 1.3e-22 79.2 1.4 3.3e-22 77.9 1.4 1.8 1 0 0 1 1 1 1 Telomere stability C-terminal SF3a60_bindingd PF12108.8 CDJ96327.1 - 1.7e-10 40.6 0.0 4.6e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 CDJ96327.1 - 0.051 14.0 0.2 0.12 12.8 0.1 1.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CDJ96327.1 - 0.15 12.9 0.1 0.46 11.5 0.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger ApbA_C PF08546.11 CDJ96327.1 - 0.16 12.2 0.6 0.39 10.9 0.6 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Phosphodiest PF01663.22 CDJ96329.1 - 2e-12 47.4 1.2 3.5e-09 36.7 0.1 2.1 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase WD40 PF00400.32 CDJ96331.1 - 7.1e-29 99.5 1.6 0.00018 22.2 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat CSTF1_dimer PF16699.5 CDJ96331.1 - 2.6e-23 81.6 0.1 4.3e-23 80.8 0.1 1.4 1 0 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain ANAPC4_WD40 PF12894.7 CDJ96331.1 - 2.1e-14 53.6 0.0 0.016 15.5 0.0 5.0 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ96331.1 - 1.6e-05 24.1 0.4 0.087 11.8 0.0 2.7 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 CDJ96331.1 - 0.0043 15.4 0.0 0.012 14.0 0.0 1.6 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 CDJ96331.1 - 0.05 12.1 0.0 0.11 11.0 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain Ribosomal_L26 PF16906.5 CDJ96332.1 - 6.1e-36 122.8 2.2 8e-36 122.4 2.2 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CDJ96332.1 - 1e-06 28.5 2.8 2.8e-06 27.1 2.8 1.8 1 0 0 1 1 1 1 KOW motif BrnT_toxin PF04365.13 CDJ96333.1 - 0.042 14.2 0.0 0.094 13.1 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system Suf PF05843.14 CDJ96334.1 - 3.7e-74 250.4 0.2 2.4e-70 237.9 0.0 4.5 4 2 1 5 5 5 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 CDJ96334.1 - 0.003 18.2 7.2 14 6.8 1.5 5.7 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ96334.1 - 0.1 13.1 0.6 6.1 7.4 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ96334.1 - 0.4 11.4 6.2 1 10.1 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat adh_short_C2 PF13561.6 CDJ96335.1 - 2.6e-43 148.3 0.7 4e-43 147.6 0.7 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDJ96335.1 - 1.7e-34 119.0 1.1 2.9e-34 118.2 1.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDJ96335.1 - 7.3e-06 26.0 0.3 2.1e-05 24.5 0.3 1.8 1 1 1 2 2 2 1 KR domain 3HCDH_N PF02737.18 CDJ96335.1 - 0.022 14.7 0.1 0.048 13.5 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 CDJ96335.1 - 0.038 13.4 0.1 0.12 11.8 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HLH PF00010.26 CDJ96336.1 - 4.6e-16 58.5 3.2 5.7e-16 58.2 2.4 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain COE1_HLH PF16423.5 CDJ96336.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain HLH PF00010.26 CDJ96337.1 - 3e-19 68.7 0.5 4.1e-19 68.3 0.5 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain FAD_binding_4 PF01565.23 CDJ96338.1 - 8.3e-11 41.8 0.0 1.4e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Filament PF00038.21 CDJ96339.1 - 1.1e-63 215.7 44.7 2.4e-62 211.3 44.7 2.1 1 1 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 CDJ96339.1 - 1.1e-11 45.1 0.0 2.4e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Lamin Tail Domain YabA PF06156.13 CDJ96339.1 - 0.0029 18.2 31.6 0.72 10.5 0.8 5.7 2 2 4 6 6 6 3 Initiation control protein YabA APG6_N PF17675.1 CDJ96339.1 - 0.0083 16.7 49.5 0.17 12.4 6.3 4.8 1 1 3 4 4 4 2 Apg6 coiled-coil region ATG16 PF08614.11 CDJ96339.1 - 0.0099 16.1 45.5 0.13 12.5 13.3 4.3 1 1 2 3 3 3 3 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 CDJ96339.1 - 0.014 15.4 39.1 0.82 9.7 10.8 4.9 1 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein SNCAIP_SNCA_bd PF16700.5 CDJ96339.1 - 0.016 14.9 0.4 0.016 14.9 0.4 2.4 3 0 0 3 3 1 0 Synphilin-1 alpha-Synuclein-binding domain CENP-F_leu_zip PF10473.9 CDJ96339.1 - 0.026 14.6 1.6 0.026 14.6 1.6 4.5 2 2 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bacillus_HBL PF05791.11 CDJ96339.1 - 0.058 13.2 19.0 0.84 9.4 1.9 4.3 2 1 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Laminin_II PF06009.12 CDJ96339.1 - 0.26 11.3 19.8 0.25 11.4 2.2 4.7 3 2 2 5 5 5 0 Laminin Domain II DivIC PF04977.15 CDJ96339.1 - 0.26 11.1 38.4 0.9 9.4 3.3 6.7 4 3 2 6 6 6 0 Septum formation initiator BLOC1_2 PF10046.9 CDJ96339.1 - 0.32 11.3 19.4 3.5 8.0 0.2 5.1 3 2 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prominin PF05478.11 CDJ96339.1 - 0.4 8.6 18.6 0.018 13.0 7.3 2.7 1 1 2 3 3 3 0 Prominin CCDC144C PF14915.6 CDJ96339.1 - 0.44 9.6 38.2 0.13 11.4 2.0 4.1 1 1 3 4 4 4 0 CCDC144C protein coiled-coil region Sec34 PF04136.15 CDJ96339.1 - 0.47 10.3 15.4 1.4 8.8 2.2 4.0 3 2 1 4 4 4 0 Sec34-like family Fib_alpha PF08702.10 CDJ96339.1 - 0.81 9.9 24.0 3.1 8.0 5.1 4.3 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family SOGA PF11365.8 CDJ96339.1 - 1.3 10.1 29.9 1.4 10.1 0.5 5.8 1 1 4 6 6 6 0 Protein SOGA ABC_tran_CTD PF16326.5 CDJ96339.1 - 3.2 8.1 31.6 0.058 13.7 3.6 5.4 4 2 1 5 5 5 0 ABC transporter C-terminal domain DHR10 PF18595.1 CDJ96339.1 - 4.3 7.4 45.8 0.029 14.4 4.1 5.2 2 2 3 5 5 5 0 Designed helical repeat protein 10 domain Golgin_A5 PF09787.9 CDJ96339.1 - 5 6.5 41.7 4.3 6.7 13.8 3.7 1 1 3 4 4 4 0 Golgin subfamily A member 5 DUF4140 PF13600.6 CDJ96339.1 - 6.9 7.2 31.7 8.8 6.8 0.0 6.3 3 2 3 6 6 6 0 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.11 CDJ96339.1 - 7 5.4 38.2 0.39 9.5 7.8 3.7 1 1 1 3 3 3 0 Spc7 kinetochore protein Occludin_ELL PF07303.13 CDJ96339.1 - 9.5 7.0 20.3 4.1 8.2 1.5 4.6 2 1 2 4 4 4 0 Occludin homology domain DM PF00751.18 CDJ96340.1 - 5.8e-23 80.5 11.5 8.6e-23 80.0 11.5 1.3 1 0 0 1 1 1 1 DM DNA binding domain Pex14_N PF04695.13 CDJ96340.1 - 0.02 15.5 2.0 0.02 15.5 2.0 1.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Anp1 PF03452.14 CDJ96340.1 - 0.2 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Anp1 MADF_DNA_bdg PF10545.9 CDJ96341.1 - 3.6e-20 72.1 0.4 3.6e-20 72.1 0.4 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 CDJ96341.1 - 0.00057 19.9 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain BESS PF02944.20 CDJ96341.1 - 0.0077 16.0 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 BESS motif vATP-synt_E PF01991.18 CDJ96341.1 - 0.019 14.4 0.5 0.032 13.6 0.5 1.3 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit MFS_1 PF07690.16 CDJ96342.1 - 7.5e-45 153.4 17.1 1.1e-44 152.9 17.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ96342.1 - 1.3e-08 34.1 9.6 5e-08 32.2 9.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 CDJ96342.1 - 0.0013 17.6 13.7 0.078 11.8 13.7 2.2 1 1 0 1 1 1 1 MFS_1 like family MFS_3 PF05977.13 CDJ96342.1 - 0.01 14.3 9.4 0.17 10.2 0.7 2.3 2 1 0 2 2 2 0 Transmembrane secretion effector TB2_DP1_HVA22 PF03134.19 CDJ96343.1 - 0.00055 19.8 0.9 0.00055 19.8 0.9 2.4 2 1 1 3 3 3 2 TB2/DP1, HVA22 family EF-hand_1 PF00036.32 CDJ96344.1 - 3.4e-18 63.8 3.9 9.9e-09 34.1 0.1 2.8 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CDJ96344.1 - 3.2e-15 56.3 1.9 3.5e-15 56.2 0.1 1.9 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ96344.1 - 1e-14 53.1 3.7 3.4e-08 32.8 0.2 3.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 CDJ96344.1 - 2.4e-10 39.4 0.3 0.00021 20.6 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDJ96344.1 - 1.2e-09 37.8 0.5 4.9e-09 35.9 0.4 2.1 1 1 0 1 1 1 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ96344.1 - 0.0017 18.6 0.2 0.0056 17.0 0.1 1.9 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CDJ96344.1 - 0.014 15.7 0.2 0.037 14.4 0.1 1.7 2 0 0 2 2 2 0 EF-hand domain EF-hand_4 PF12763.7 CDJ96344.1 - 0.046 13.7 0.1 0.19 11.7 0.1 1.9 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Ras PF00071.22 CDJ96345.1 - 5.3e-19 68.4 0.0 1.2e-18 67.3 0.0 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CDJ96345.1 - 1.3e-10 41.5 0.0 9.9e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 CDJ96345.1 - 0.018 14.5 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 CDJ96345.1 - 0.071 13.5 0.0 0.13 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain KH_1 PF00013.29 CDJ96348.1 - 1.4e-170 553.3 49.6 7.6e-16 57.7 1.6 15.2 15 0 0 15 15 15 15 KH domain SLS PF14611.6 CDJ96348.1 - 1.3e-19 71.0 25.2 0.00012 22.0 0.6 9.0 4 3 5 9 9 9 6 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 CDJ96348.1 - 2.2e-09 37.0 42.5 0.039 13.8 4.3 10.2 9 3 1 10 10 10 4 KH domain KH_4 PF13083.6 CDJ96348.1 - 0.21 11.5 0.0 0.21 11.5 0.0 8.2 9 1 2 11 11 11 0 KH domain YbbR PF07949.12 CDJ96348.1 - 0.23 11.8 28.5 2 8.8 0.1 7.9 9 0 0 9 9 9 0 YbbR-like protein DUF2096 PF09869.9 CDJ96348.1 - 5.1 7.1 24.5 2.6 8.1 0.6 8.3 7 3 3 11 11 11 0 Uncharacterized protein conserved in archaea (DUF2096) Fra10Ac1 PF09725.9 CDJ96349.1 - 9.2e-13 48.4 1.8 1.5e-12 47.7 0.5 1.9 2 0 0 2 2 2 1 Folate-sensitive fragile site protein Fra10Ac1 Homeodomain PF00046.29 CDJ96350.1 - 7e-14 51.4 2.5 9.4e-14 51.0 1.6 1.7 2 0 0 2 2 2 1 Homeodomain HSP20 PF00011.21 CDJ96352.1 - 4.4e-20 71.7 0.1 5e-20 71.6 0.1 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ96352.1 - 0.0097 15.4 0.0 0.013 15.1 0.0 1.3 1 1 0 1 1 1 1 HSP20-like domain found in ArsA LEM PF03020.15 CDJ96354.1 - 8.1e-12 44.5 0.0 1.2e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 LEM domain Glucosamine_iso PF01182.20 CDJ96355.1 - 3.3e-19 69.7 0.0 3.8e-19 69.5 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Integrase_DNA PF02920.15 CDJ96356.1 - 0.11 12.2 2.5 2.1 8.1 0.1 2.2 2 0 0 2 2 2 0 DNA binding domain of tn916 integrase RVT_1 PF00078.27 CDJ96357.1 - 5.4e-12 45.7 0.0 6e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Adeno_Penton_B PF01686.17 CDJ96357.1 - 0.093 11.2 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Adenovirus penton base protein RVT_1 PF00078.27 CDJ96358.1 - 1.2e-14 54.4 0.0 1.5e-14 54.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CDJ96362.1 - 8.1e-05 22.2 0.0 0.00019 21.1 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CLP1_P PF16575.5 CDJ96365.1 - 3.7e-29 101.8 0.0 5.4e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 CDJ96365.1 - 0.0071 16.5 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ96365.1 - 0.0087 16.5 0.0 0.028 14.8 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_PrkA PF08298.11 CDJ96365.1 - 0.014 14.4 0.0 0.017 14.1 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain ATPase_2 PF01637.18 CDJ96365.1 - 0.014 15.3 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 CDJ96365.1 - 0.019 15.5 0.0 0.032 14.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 CDJ96365.1 - 0.022 14.7 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 CDJ96365.1 - 0.029 14.6 0.0 0.088 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CDJ96365.1 - 0.029 14.6 0.0 0.045 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain RHD3 PF05879.12 CDJ96365.1 - 0.038 12.1 0.1 0.053 11.7 0.1 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Adeno_IVa2 PF02456.15 CDJ96365.1 - 0.049 12.4 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein cobW PF02492.19 CDJ96365.1 - 0.07 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain APS_kinase PF01583.20 CDJ96365.1 - 0.073 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase Roc PF08477.13 CDJ96365.1 - 0.081 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase CbiA PF01656.23 CDJ96365.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 CDJ96365.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 CDJ96365.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF815 PF05673.13 CDJ96365.1 - 0.15 11.2 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 CDJ96365.1 - 0.17 11.9 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase MipZ PF09140.11 CDJ96365.1 - 0.21 10.8 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ Biotin_lipoyl PF00364.22 CDJ96366.1 - 1.2e-18 66.7 0.1 2e-18 65.9 0.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CDJ96366.1 - 4.4e-12 46.1 0.6 8.4e-12 45.2 0.6 1.5 1 0 0 1 1 1 1 e3 binding domain 2-oxoacid_dh PF00198.23 CDJ96366.1 - 2e-08 33.9 0.0 2.6e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl_2 PF13533.6 CDJ96366.1 - 0.16 11.8 0.0 0.41 10.5 0.0 1.6 2 0 0 2 2 2 0 Biotin-lipoyl like FERM_C PF09380.10 CDJ96367.1 - 2.9e-15 56.4 0.0 5.9e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 CDJ96367.1 - 4.6e-15 56.1 0.0 1.2e-14 54.7 0.0 1.7 1 0 0 1 1 1 1 FERM central domain XRCC4 PF06632.12 CDJ96367.1 - 0.02 13.7 2.3 0.029 13.2 2.3 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 SKA1 PF07160.12 CDJ96368.1 - 2.3e-30 106.2 1.1 2.3e-30 106.2 1.1 1.7 2 1 0 2 2 2 1 Spindle and kinetochore-associated protein 1 DUF3161 PF11362.8 CDJ96368.1 - 0.031 14.3 0.6 0.12 12.4 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3161) MtN3_slv PF03083.16 CDJ96369.1 - 2.4e-16 59.6 17.2 4e-09 36.4 2.1 2.4 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange SRCR PF00530.18 CDJ96370.1 - 1.7e-29 102.2 6.1 9.5e-17 61.3 0.7 2.6 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 CDJ96370.1 - 2.1e-05 24.9 5.1 0.002 18.6 0.1 3.5 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain MAP17 PF15807.5 CDJ96370.1 - 3.4e-05 24.1 0.0 6.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Lectin_C PF00059.21 CDJ96370.1 - 0.00052 20.7 0.1 0.0021 18.8 0.1 2.1 1 1 0 1 1 1 1 Lectin C-type domain Hepsin-SRCR PF09272.10 CDJ96370.1 - 0.0025 18.3 0.3 0.047 14.2 0.1 2.5 2 0 0 2 2 2 1 Hepsin, SRCR domain TMEM51 PF15345.6 CDJ96370.1 - 0.026 14.4 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 FixS PF03597.15 CDJ96370.1 - 1 9.1 4.9 2.5 7.9 4.9 1.6 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Gal-bind_lectin PF00337.22 CDJ96371.1 - 4.9e-35 120.0 0.0 5.4e-35 119.8 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin Mucin_bdg PF03272.13 CDJ96371.1 - 0.018 15.0 0.0 0.025 14.6 0.0 1.2 1 0 0 1 1 1 0 Putative mucin or carbohydrate-binding module Alginate_lyase2 PF08787.11 CDJ96371.1 - 0.034 14.0 0.0 0.037 13.9 0.0 1.1 1 0 0 1 1 1 0 Alginate lyase Myosin_TH1 PF06017.13 CDJ96371.1 - 0.062 13.0 0.0 0.75 9.4 0.0 2.0 1 1 1 2 2 2 0 Unconventional myosin tail, actin- and lipid-binding Metallophos PF00149.28 CDJ96372.1 - 9.4e-41 140.6 0.1 1.2e-40 140.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDJ96372.1 - 1.9e-23 82.6 1.6 3.6e-23 81.7 1.0 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain MH2 PF03166.14 CDJ96373.1 - 1.9e-48 165.2 0.0 2.7e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 CDJ96373.1 - 6.5e-34 116.2 0.2 1.1e-33 115.5 0.2 1.4 1 0 0 1 1 1 1 MH1 domain DUF1955 PF09205.10 CDJ96373.1 - 3.4e-05 23.6 0.0 5.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1955) DNA_pol_E_B PF04042.16 CDJ96374.1 - 0.064 12.6 0.1 0.095 12.0 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B DUF802 PF05650.11 CDJ96374.1 - 0.087 13.3 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF802) fn3 PF00041.21 CDJ96375.1 - 4e-15 55.9 1.7 0.00027 21.2 0.1 3.3 3 0 0 3 3 3 3 Fibronectin type III domain Prominin PF05478.11 CDJ96375.1 - 0.00028 19.0 1.7 0.00038 18.6 1.7 1.1 1 0 0 1 1 1 1 Prominin UDPGT PF00201.18 CDJ96378.1 - 7e-31 107.6 0.0 8.4e-31 107.3 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Antimicrobial_7 PF08102.11 CDJ96378.1 - 0.092 13.0 0.5 22 5.4 0.0 3.3 3 0 0 3 3 3 0 Scorpion antimicrobial peptide Glyco_transf_4 PF13439.6 CDJ96378.1 - 0.14 12.2 0.0 0.45 10.5 0.0 1.8 1 1 0 1 1 1 0 Glycosyltransferase Family 4 His_Phos_2 PF00328.22 CDJ96379.1 - 2.7e-28 99.4 0.5 1.6e-24 87.0 0.5 2.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) zf-MYND PF01753.18 CDJ96381.1 - 7.3e-11 42.0 12.9 7.3e-11 42.0 12.9 3.6 4 0 0 4 4 4 1 MYND finger Clathrin PF00637.20 CDJ96381.1 - 4e-10 39.7 8.4 1.7e-09 37.7 0.8 3.3 3 0 0 3 3 3 1 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 CDJ96381.1 - 2.8e-05 24.1 10.7 0.00013 21.9 10.7 2.3 1 0 0 1 1 1 1 Zinc-finger zf-rbx1 PF12678.7 CDJ96381.1 - 0.0018 18.5 5.2 0.0018 18.5 5.2 2.6 3 0 0 3 3 3 1 RING-H2 zinc finger domain TPR_12 PF13424.6 CDJ96381.1 - 0.65 10.3 4.2 2 8.8 0.7 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_8 PF05148.15 CDJ96382.1 - 9e-98 326.5 0.1 1.3e-97 326.0 0.1 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 CDJ96382.1 - 1.8e-06 28.5 0.1 1.7e-05 25.4 0.1 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ96382.1 - 8.4e-05 23.2 0.2 0.011 16.4 0.1 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ96382.1 - 0.0012 18.6 2.5 0.34 10.7 0.0 2.7 2 1 0 3 3 3 2 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ96382.1 - 0.0014 18.0 0.2 0.031 13.6 0.0 2.3 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 CDJ96382.1 - 0.016 14.8 0.1 0.04 13.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain MetW PF07021.12 CDJ96382.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW NOG1_N PF17835.1 CDJ96383.1 - 2.5e-51 173.8 2.0 2.5e-51 173.8 2.0 2.6 3 0 0 3 3 3 1 NOG1 N-terminal helical domain NOG1 PF06858.14 CDJ96383.1 - 8.7e-26 89.5 0.2 2.5e-25 88.0 0.2 1.9 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 CDJ96383.1 - 3e-22 78.4 1.3 3e-22 78.4 1.3 2.6 3 0 0 3 3 3 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 CDJ96383.1 - 1.7e-18 66.7 0.0 4.3e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ96383.1 - 1.6e-14 53.7 0.0 3.9e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 CDJ96383.1 - 2.9e-05 23.5 0.7 0.0011 18.4 0.0 2.6 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 CDJ96383.1 - 4.8e-05 23.3 0.9 0.44 10.4 0.0 3.2 3 1 0 3 3 3 2 RsgA GTPase Dynamin_N PF00350.23 CDJ96383.1 - 0.00019 21.5 2.4 0.3 11.1 0.0 3.2 2 1 1 3 3 3 2 Dynamin family MUG113 PF13455.6 CDJ96383.1 - 0.042 14.5 0.7 0.39 11.4 0.3 2.8 2 0 0 2 2 2 0 Meiotically up-regulated gene 113 Roc PF08477.13 CDJ96383.1 - 0.093 13.0 0.0 0.9 9.8 0.0 2.6 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Asp_protease PF09668.10 CDJ96384.1 - 2.6e-52 175.8 0.3 6.6e-52 174.5 0.2 1.7 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ96384.1 - 3.7e-20 72.3 0.0 1.1e-19 70.8 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ96384.1 - 6.7e-09 36.3 0.0 1.5e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CDJ96384.1 - 2.3e-06 27.4 0.0 5.6e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA PF00627.31 CDJ96384.1 - 0.00024 20.9 0.9 0.00065 19.5 0.9 1.8 1 0 0 1 1 1 1 UBA/TS-N domain RVP PF00077.20 CDJ96384.1 - 0.00069 19.9 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.6 CDJ96384.1 - 0.0069 16.2 0.2 0.018 14.9 0.2 1.6 1 0 0 1 1 1 1 UBA-like domain RuvA_C PF07499.13 CDJ96384.1 - 0.061 13.8 0.2 0.32 11.5 0.0 2.3 2 0 0 2 2 2 0 RuvA, C-terminal domain ubiquitin PF00240.23 CDJ96384.1 - 0.065 13.0 0.0 2.4 8.0 0.0 2.7 2 0 0 2 2 2 0 Ubiquitin family DUF1160 PF06648.11 CDJ96384.1 - 0.072 13.1 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) X PF00739.19 CDJ96384.1 - 0.63 10.2 3.2 1.3 9.1 0.4 2.7 3 0 0 3 3 3 0 Trans-activation protein X RNase_T PF00929.24 CDJ96385.1 - 5.6e-30 105.1 0.0 1.2e-29 104.0 0.0 1.6 1 0 0 1 1 1 1 Exonuclease Skp1 PF01466.19 CDJ96385.1 - 8.9e-24 83.4 0.0 8.9e-24 83.4 0.0 2.2 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 CDJ96385.1 - 7.3e-17 61.3 1.6 2e-16 59.9 1.6 1.8 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain SAP PF02037.27 CDJ96385.1 - 0.0019 17.9 0.1 0.0042 16.8 0.1 1.6 1 0 0 1 1 1 1 SAP domain Elongin_A PF06881.11 CDJ96385.1 - 0.34 11.5 4.1 0.92 10.1 1.2 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Tmemb_185A PF10269.9 CDJ96386.1 - 4.3e-06 26.6 1.1 4.9e-06 26.4 1.1 1.1 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein rve PF00665.26 CDJ96388.1 - 4.4e-42 143.0 0.1 4.8e-22 78.4 0.0 2.9 2 0 0 2 2 2 2 Integrase core domain RT_RNaseH_2 PF17919.1 CDJ96388.1 - 2.9e-36 123.5 0.0 2e-35 120.8 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ96388.1 - 1.8e-33 115.0 0.0 1.9e-32 111.7 0.0 2.6 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ96388.1 - 1.8e-21 76.7 0.0 3.5e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ96388.1 - 1.9e-17 63.1 0.1 3.9e-17 62.1 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CDJ96388.1 - 4.2e-12 45.7 0.0 0.00018 21.3 0.0 3.1 2 0 0 2 2 2 2 Integrase core domain gag-asp_proteas PF13975.6 CDJ96388.1 - 0.0011 19.5 0.0 0.0023 18.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF3567 PF12091.8 CDJ96388.1 - 0.0062 16.6 0.0 4.4 7.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3567) zf-H2C2 PF09337.10 CDJ96388.1 - 0.051 13.8 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease_2 PF13650.6 CDJ96388.1 - 0.096 13.3 0.0 0.28 11.9 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease ThiF PF00899.21 CDJ96389.1 - 1.4e-48 165.4 0.2 2e-48 164.9 0.2 1.1 1 0 0 1 1 1 1 ThiF family ECSIT PF06239.11 CDJ96389.1 - 0.0017 17.6 0.1 0.077 12.1 0.0 2.3 2 0 0 2 2 2 1 Evolutionarily conserved signalling intermediate in Toll pathway 2-Hacid_dh_C PF02826.19 CDJ96389.1 - 0.018 14.4 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 CDJ96389.1 - 0.023 14.3 0.1 0.078 12.6 0.1 2.0 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 CDJ96389.1 - 0.037 13.6 0.2 0.092 12.3 0.1 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 CDJ96389.1 - 0.11 12.7 3.7 0.92 9.8 1.6 2.7 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain SOGA PF11365.8 CDJ96389.1 - 0.18 12.9 1.4 0.33 12.1 0.2 2.1 2 0 0 2 2 2 0 Protein SOGA SYS1 PF09801.9 CDJ96390.1 - 1.5e-35 122.4 14.0 2.1e-35 122.0 14.0 1.2 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network BOP1NT PF08145.12 CDJ96391.1 - 2.2e-95 319.5 8.0 2.2e-95 319.5 8.0 1.7 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.32 CDJ96391.1 - 1.2e-17 63.9 1.4 0.00082 20.1 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ96391.1 - 1.9e-08 34.5 0.1 0.031 14.6 0.0 5.2 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2118 PF09891.9 CDJ96391.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) PAN_1 PF00024.26 CDJ96392.1 - 3.6e-52 174.3 29.3 7.1e-11 41.9 0.4 6.5 5 1 1 6 6 6 6 PAN domain Zona_pellucida PF00100.23 CDJ96392.1 - 7.1e-07 29.3 0.0 2.6e-06 27.4 0.0 2.1 1 0 0 1 1 1 1 Zona pellucida-like domain PAN_3 PF08277.12 CDJ96392.1 - 0.00025 20.8 22.1 0.011 15.6 0.1 5.8 7 0 0 7 7 7 3 PAN-like domain PAN_4 PF14295.6 CDJ96392.1 - 0.00058 19.7 24.3 0.44 10.5 0.3 6.2 6 1 0 6 6 6 3 PAN domain tRNA-synt_1d PF00750.19 CDJ96392.1 - 0.082 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (R) PTR2 PF00854.21 CDJ96394.1 - 2.1e-12 46.6 1.5 2.4e-12 46.4 1.5 1.1 1 0 0 1 1 1 1 POT family ATP_bind_1 PF03029.17 CDJ96394.1 - 0.066 13.0 0.0 0.076 12.8 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Methyltransf_11 PF08241.12 CDJ96395.1 - 1.5e-15 57.6 0.0 3.2e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ96395.1 - 4.3e-11 43.4 0.1 1.2e-10 41.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ96395.1 - 1e-05 25.0 0.0 4e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 CDJ96395.1 - 3.9e-05 23.5 0.0 6.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ96395.1 - 6.8e-05 23.5 0.0 0.00015 22.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ96395.1 - 0.0011 18.9 0.0 0.0025 17.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CDJ96395.1 - 0.0052 16.7 0.0 0.011 15.6 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.20 CDJ96395.1 - 0.035 13.4 0.0 0.26 10.6 0.0 2.0 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase p450 PF00067.22 CDJ96396.1 - 4.8e-62 210.2 2.4 7.9e-62 209.5 2.4 1.3 1 1 0 1 1 1 1 Cytochrome P450 DIRP PF06584.13 CDJ96397.1 - 2.5e-20 72.6 0.0 2.6e-18 66.1 0.0 3.0 1 1 0 1 1 1 1 DIRP NPH3 PF03000.14 CDJ96397.1 - 0.016 14.9 1.0 0.026 14.2 0.2 1.7 2 0 0 2 2 2 0 NPH3 family NapB PF03892.14 CDJ96397.1 - 0.048 13.7 0.2 0.13 12.3 0.2 1.7 1 0 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) Laminin_II PF06009.12 CDJ96397.1 - 8.1 6.5 8.9 2.6 8.1 0.5 3.1 2 1 0 3 3 3 0 Laminin Domain II V_ATPase_I PF01496.19 CDJ96398.1 - 0 1056.7 0.0 0 1056.5 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Occludin_ELL PF07303.13 CDJ96398.1 - 0.36 11.6 2.6 32 5.3 0.1 3.3 3 0 0 3 3 3 0 Occludin homology domain TPK_catalytic PF04263.16 CDJ96399.1 - 1.3e-32 112.3 0.0 1.8e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 CDJ96399.1 - 1.1e-16 60.2 0.0 1.8e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Pyr_redox_2 PF07992.14 CDJ96400.1 - 2.8e-44 151.5 1.4 9.1e-30 103.9 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CDJ96400.1 - 5.3e-28 97.5 0.0 1.1e-27 96.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 CDJ96400.1 - 6.4e-11 42.0 0.1 9.5e-08 31.6 0.0 2.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CDJ96400.1 - 2.3e-08 33.5 0.8 3.6e-08 32.9 0.2 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 CDJ96400.1 - 1.4e-06 28.7 4.2 0.0058 17.2 0.0 3.2 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CDJ96400.1 - 0.00011 21.5 2.5 0.00011 21.5 2.5 2.4 2 1 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 CDJ96400.1 - 0.00023 20.0 0.4 0.003 16.3 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 CDJ96400.1 - 0.00065 19.2 0.3 0.0009 18.7 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 CDJ96400.1 - 0.0053 15.9 0.1 0.012 14.8 0.0 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 CDJ96400.1 - 0.008 15.5 1.1 0.016 14.5 1.1 1.4 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 CDJ96400.1 - 0.018 14.4 0.8 0.49 9.7 0.1 2.6 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 CDJ96400.1 - 0.05 13.8 1.1 0.05 13.8 1.1 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CDJ96400.1 - 0.091 12.3 7.3 0.61 9.6 5.1 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase HTH_psq PF05225.16 CDJ96400.1 - 0.14 11.9 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain PSP PF04046.16 CDJ96401.1 - 2.1e-14 53.1 0.0 5.1e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 PSP zf-C2H2_6 PF13912.6 CDJ96402.1 - 0.24 11.4 17.2 0.64 10.1 0.1 7.3 5 0 0 5 5 5 0 C2H2-type zinc finger DLIC PF05783.11 CDJ96403.1 - 1.9e-71 241.3 0.1 7.7e-71 239.3 0.1 1.9 1 1 0 1 1 1 1 Dynein light intermediate chain (DLIC) Ras PF00071.22 CDJ96403.1 - 0.00016 21.3 0.0 0.35 10.4 0.0 2.6 2 1 0 2 2 2 2 Ras family RsgA_GTPase PF03193.16 CDJ96403.1 - 0.00023 21.1 1.8 0.19 11.6 0.0 2.6 3 0 0 3 3 3 2 RsgA GTPase Roc PF08477.13 CDJ96403.1 - 0.0025 18.0 0.0 0.0078 16.4 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 CDJ96403.1 - 0.019 14.7 0.4 27 4.5 0.0 3.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 CDJ96403.1 - 0.07 13.6 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 CDJ96403.1 - 0.1 12.4 0.7 0.24 11.1 0.7 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arf PF00025.21 CDJ96403.1 - 0.14 11.6 0.1 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_16 PF13191.6 CDJ96403.1 - 0.16 12.4 2.0 0.81 10.1 0.0 2.7 2 1 1 3 3 3 0 AAA ATPase domain JAB PF01398.21 CDJ96405.1 - 4.5e-32 110.5 0.0 7.6e-32 109.8 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 CDJ96405.1 - 3.1e-16 60.1 0.2 5.9e-15 56.0 0.0 2.7 2 1 0 2 2 2 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 CDJ96405.1 - 2.7e-05 23.9 0.0 5.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 CDJ96405.1 - 0.038 14.0 0.0 0.087 12.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Pkinase PF00069.25 CDJ96406.1 - 6.5e-66 222.4 0.0 9e-66 221.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ96406.1 - 2.4e-32 112.3 0.0 4.4e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ96406.1 - 1.2e-05 24.8 0.0 1.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CDJ96406.1 - 0.00034 19.7 0.0 0.0011 18.0 0.0 1.8 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CDJ96406.1 - 0.0036 17.3 0.2 0.024 14.5 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ96406.1 - 0.0092 15.4 0.2 0.047 13.1 0.2 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CDJ96406.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 TruD PF01142.18 CDJ96407.1 - 3.8e-61 207.2 0.0 1.5e-59 201.9 0.0 2.1 1 1 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) ubiquitin PF00240.23 CDJ96407.1 - 9.1e-05 22.1 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family F-box PF00646.33 CDJ96407.1 - 0.0039 17.0 0.2 0.0095 15.8 0.2 1.6 1 0 0 1 1 1 1 F-box domain YukD PF08817.10 CDJ96407.1 - 0.02 15.6 0.0 0.054 14.2 0.0 1.8 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_4 PF18036.1 CDJ96407.1 - 0.051 13.6 0.0 0.16 12.0 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_2 PF14560.6 CDJ96407.1 - 0.084 13.3 0.0 0.36 11.3 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain HxlR PF01638.17 CDJ96407.1 - 0.1 12.4 0.0 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 HxlR-like helix-turn-helix UN_NPL4 PF11543.8 CDJ96407.1 - 0.16 12.4 0.0 0.35 11.4 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 RNB PF00773.19 CDJ96408.1 - 5.1e-31 108.2 0.1 5.5e-31 108.1 0.1 1.0 1 0 0 1 1 1 1 RNB domain SPT16 PF08644.11 CDJ96410.1 - 0.12 12.5 0.4 0.12 12.5 0.4 2.1 2 1 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) Fusion_F0 PF13044.6 CDJ96410.1 - 0.15 10.7 0.1 0.18 10.4 0.1 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0, Isavirus BRO1 PF03097.18 CDJ96411.1 - 6e-82 275.5 4.4 7.7e-82 275.2 4.4 1.1 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CDJ96411.1 - 1.1e-16 61.0 1.5 1.1e-16 61.0 1.5 2.9 4 0 0 4 4 4 1 ALIX V-shaped domain binding to HIV 7tm_1 PF00001.21 CDJ96412.1 - 0.0027 17.1 17.5 0.0063 15.9 17.3 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srd PF10317.9 CDJ96412.1 - 0.061 12.5 22.0 0.2 10.8 17.1 2.8 1 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srd CAAD PF14159.6 CDJ96412.1 - 0.11 12.3 0.2 0.11 12.3 0.2 3.0 3 1 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Oxidored_q2 PF00420.24 CDJ96412.1 - 0.38 10.4 16.0 0.027 14.1 2.9 3.2 2 1 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Glyco_transf_7C PF02709.14 CDJ96413.1 - 2.5e-25 87.9 0.1 4.7e-25 87.1 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 CDJ96413.1 - 2e-22 79.3 0.0 3e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 ATP-synt_C PF00137.21 CDJ96414.1 - 5.7e-34 116.3 34.5 8.8e-21 74.0 15.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ATP-synt_C PF00137.21 CDJ96415.1 - 3e-35 120.4 35.3 2.7e-22 78.9 13.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CrgA PF06781.12 CDJ96415.1 - 0.13 12.3 3.3 0.28 11.3 0.6 2.2 2 0 0 2 2 2 0 Cell division protein CrgA DUF2970 PF11174.8 CDJ96415.1 - 2.6 8.0 7.9 0.66 9.9 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) RNase_PH PF01138.21 CDJ96417.1 - 1.4e-08 35.3 0.4 5.1e-08 33.5 0.1 2.1 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Recep_L_domain PF01030.24 CDJ96418.1 - 4e-12 46.2 0.2 6.5e-12 45.6 0.2 1.3 1 0 0 1 1 1 1 Receptor L domain Pkinase PF00069.25 CDJ96419.1 - 5.7e-66 222.6 0.0 8.2e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ96419.1 - 3.6e-39 134.6 0.0 5.3e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ96419.1 - 9.4e-06 25.1 0.0 1.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDJ96419.1 - 0.00071 19.0 0.2 0.0013 18.1 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ96419.1 - 0.0065 16.4 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CDJ96419.1 - 0.012 14.7 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 CDJ96419.1 - 0.076 11.8 0.2 0.15 10.8 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase TRAM_LAG1_CLN8 PF03798.16 CDJ96420.1 - 6.6e-34 117.4 20.7 9.2e-34 116.9 20.7 1.2 1 0 0 1 1 1 1 TLC domain DUF4834 PF16118.5 CDJ96420.1 - 0.0085 17.0 0.1 0.018 16.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) BROMI PF14961.6 CDJ96421.1 - 0.014 12.9 0.0 0.015 12.7 0.0 1.1 1 0 0 1 1 1 0 Broad-minded protein DDE_Tnp_1_7 PF13843.6 CDJ96424.1 - 0.00084 18.7 0.1 0.001 18.5 0.1 1.1 1 0 0 1 1 1 1 Transposase IS4 Keratin_2_head PF16208.5 CDJ96426.1 - 0.002 18.3 15.6 0.0022 18.1 15.6 1.1 1 0 0 1 1 1 1 Keratin type II head KRTAP PF11759.8 CDJ96426.1 - 0.017 15.7 13.6 0.025 15.1 13.6 1.3 1 0 0 1 1 1 0 Keratin-associated matrix Peptidase_A17 PF05380.13 CDJ96427.1 - 4.2e-20 72.4 0.3 5.8e-20 71.9 0.3 1.2 1 0 0 1 1 1 1 Pao retrotransposon peptidase RT_RNaseH PF17917.1 CDJ96427.1 - 0.0046 17.2 0.1 0.0072 16.6 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ96427.1 - 0.0056 16.7 0.1 0.0098 15.9 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TPR_1 PF00515.28 CDJ96428.1 - 1.4e-10 40.5 0.3 0.00054 19.7 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ96428.1 - 9.5e-10 37.8 3.8 0.0012 18.8 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ96428.1 - 1.6e-07 31.8 0.0 0.0018 18.9 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ96428.1 - 9.2e-07 29.3 0.1 0.00021 21.7 0.1 3.3 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ96428.1 - 3e-06 26.8 1.0 0.33 10.7 0.0 3.9 4 0 0 4 4 4 2 TPR repeat TPR_8 PF13181.6 CDJ96428.1 - 0.00011 22.1 1.4 0.14 12.4 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ96428.1 - 0.00043 20.5 0.2 0.92 9.8 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ96428.1 - 0.00081 20.0 4.8 7.5 7.7 0.2 5.6 3 1 3 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ96428.1 - 0.0012 19.1 0.3 31 5.2 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ96428.1 - 0.0028 17.8 0.2 0.022 14.9 0.0 2.5 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CDJ96428.1 - 0.0035 17.9 0.3 0.23 12.2 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF5588 PF17826.1 CDJ96428.1 - 0.0088 15.0 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5588) TPR_9 PF13371.6 CDJ96428.1 - 0.024 14.8 0.5 0.15 12.3 0.1 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ96428.1 - 0.11 12.5 0.2 10 6.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 CDJ96428.1 - 0.12 12.1 0.1 0.71 9.6 0.1 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain DUF229 PF02995.17 CDJ96430.1 - 2.3e-53 181.5 2.2 2e-34 119.0 0.1 2.4 1 1 2 3 3 3 2 Protein of unknown function (DUF229) zf-C2H2_4 PF13894.6 CDJ96432.1 - 0.0029 18.3 4.5 0.007 17.1 4.5 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDJ96432.1 - 0.003 17.5 4.6 0.0058 16.6 4.6 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 CDJ96432.1 - 0.011 16.1 5.6 0.023 15.1 5.6 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-met PF12874.7 CDJ96432.1 - 0.016 15.6 3.7 0.029 14.8 3.7 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CDJ96432.1 - 0.062 13.6 0.9 0.096 13.0 0.9 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CDJ96432.1 - 0.19 12.1 5.0 0.34 11.3 5.0 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CDJ96432.1 - 2.7 8.6 5.7 12 6.5 1.4 2.3 2 0 0 2 2 2 0 Zinc-finger double domain DUF2914 PF11141.8 CDJ96433.1 - 0.15 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) 3HCDH_N PF02737.18 CDJ96434.1 - 4.9e-55 186.2 0.1 6.4e-55 185.8 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 CDJ96434.1 - 1.1e-32 112.5 0.0 1.1e-31 109.3 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CDJ96434.1 - 8.3e-09 35.8 0.8 3.7e-07 30.5 0.8 2.2 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 CDJ96434.1 - 0.00096 19.2 0.3 0.0098 15.9 0.3 2.1 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 CDJ96434.1 - 0.0014 18.0 0.5 0.03 13.7 0.1 2.1 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 CDJ96434.1 - 0.0023 18.5 0.1 0.0041 17.6 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 CDJ96434.1 - 0.0054 17.3 0.2 0.01 16.4 0.2 1.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.14 CDJ96434.1 - 0.026 13.7 0.2 0.036 13.3 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 CDJ96434.1 - 0.064 12.7 0.5 1.7 8.1 0.2 2.1 1 1 1 2 2 2 0 short chain dehydrogenase GTP_EFTU PF00009.27 CDJ96435.1 - 1.5e-21 76.9 0.0 2.7e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CDJ96435.1 - 2.3e-09 37.5 0.2 6.6e-08 32.8 0.1 2.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 CDJ96435.1 - 0.0001 22.6 0.3 0.00044 20.5 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 CDJ96435.1 - 0.00091 19.3 0.5 0.0025 17.9 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CDJ96435.1 - 0.05 13.4 0.0 42 3.9 0.0 3.4 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation HTH_Mga PF08280.11 CDJ96437.1 - 0.014 15.5 0.2 0.018 15.0 0.2 1.2 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain NIF PF03031.18 CDJ96438.1 - 4.2e-37 127.3 0.4 6.3e-37 126.7 0.4 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Peptidase_M28 PF04389.17 CDJ96439.1 - 3.8e-38 131.2 0.0 5e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Gly-zipper_OmpA PF13436.6 CDJ96440.1 - 0.013 15.2 1.0 0.013 15.2 1.0 2.0 2 0 0 2 2 2 0 Glycine-zipper domain Chorion_3 PF05387.11 CDJ96441.1 - 0.036 13.7 3.1 0.037 13.7 3.1 1.0 1 0 0 1 1 1 0 Chorion family 3 DUF347 PF03988.12 CDJ96441.1 - 0.18 12.1 4.5 0.18 12.0 0.2 2.1 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) Exo_endo_phos PF03372.23 CDJ96442.1 - 2.5e-05 23.9 0.0 2.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Sec15 PF04091.12 CDJ96443.1 - 5.1e-79 266.0 1.1 5.1e-79 266.0 1.1 1.8 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Vps51 PF08700.11 CDJ96443.1 - 0.00011 22.1 0.5 0.00078 19.5 0.0 2.7 2 1 0 2 2 2 1 Vps51/Vps67 Sec8_exocyst PF04048.14 CDJ96443.1 - 0.19 11.6 5.5 0.16 11.9 0.8 2.8 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain Herpes_UL36 PF03586.13 CDJ96443.1 - 0.28 10.5 2.5 0.54 9.5 0.2 2.3 2 0 0 2 2 2 0 Herpesvirus UL36 tegument protein COG2 PF06148.11 CDJ96443.1 - 0.59 10.2 6.1 0.72 9.9 2.4 3.0 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1681 PF07933.14 CDJ96444.1 - 8.8e-51 171.5 0.0 1e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) UQ_con PF00179.26 CDJ96445.1 - 1.6e-19 70.0 0.0 2.2e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UQ_con PF00179.26 CDJ96446.1 - 1.1e-20 73.7 0.0 1.4e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ96446.1 - 0.031 14.0 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B Galactosyl_T PF01762.21 CDJ96447.1 - 1e-28 100.5 0.0 1.5e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase GWT1 PF06423.12 CDJ96447.1 - 1.3e-23 83.8 6.6 1.3e-23 83.8 6.6 2.9 2 1 0 2 2 2 1 GWT1 PCI PF01399.27 CDJ96448.1 - 1.9e-12 47.6 0.0 6.6e-12 45.9 0.0 2.0 1 0 0 1 1 1 1 PCI domain adh_short PF00106.25 CDJ96449.1 - 1.5e-26 93.1 0.1 8.1e-22 77.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ96449.1 - 6e-15 55.4 0.0 2.8e-13 50.0 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ96449.1 - 1.4e-09 38.1 0.2 3.2e-09 37.0 0.2 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CDJ96449.1 - 0.0024 17.4 0.1 0.0067 15.9 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Phage_Coat_Gp8 PF05371.12 CDJ96449.1 - 0.023 14.5 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Phage major coat protein, Gp8 SAM_MT PF04445.13 CDJ96449.1 - 0.039 13.4 0.3 0.056 12.8 0.3 1.3 1 1 0 1 1 1 0 Putative SAM-dependent methyltransferase 2-Hacid_dh_C PF02826.19 CDJ96449.1 - 0.05 13.0 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CDJ96449.1 - 0.1 12.6 0.3 0.25 11.4 0.2 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase UPF0139 PF03669.13 CDJ96450.1 - 2.4e-47 158.7 1.7 2.8e-47 158.5 1.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Rota_NSP3 PF01665.16 CDJ96451.1 - 0.0025 17.0 2.5 0.0028 16.9 2.5 1.1 1 0 0 1 1 1 1 Rotavirus non-structural protein NSP3 V_ATPase_I_N PF18670.1 CDJ96451.1 - 0.0063 16.9 0.9 0.74 10.3 0.1 2.1 2 0 0 2 2 2 2 V-type ATPase subunit I, N-terminal domain DUF724 PF05266.14 CDJ96451.1 - 0.12 12.2 4.2 0.2 11.4 4.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) ABC_tran_CTD PF16326.5 CDJ96451.1 - 0.15 12.3 11.3 4.7 7.5 2.6 3.1 1 1 1 3 3 3 0 ABC transporter C-terminal domain zf-C4H2 PF10146.9 CDJ96451.1 - 0.31 11.3 5.0 0.19 12.1 3.2 1.5 2 0 0 2 2 2 0 Zinc finger-containing protein Prefoldin_2 PF01920.20 CDJ96451.1 - 3.1 7.8 10.1 0.46 10.5 1.6 2.8 2 1 1 3 3 3 0 Prefoldin subunit Pkinase_Tyr PF07714.17 CDJ96452.1 - 2.7e-72 243.2 0.2 3.7e-72 242.7 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ96452.1 - 4.6e-47 160.6 0.0 6.5e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CDJ96452.1 - 0.0038 16.6 0.5 0.0066 15.8 0.5 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family GrlR PF16518.5 CDJ96452.1 - 0.096 12.7 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 T3SS negative regulator,GrlR Exo_endo_phos_2 PF14529.6 CDJ96454.1 - 0.00017 21.5 0.9 0.00056 19.7 0.1 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ96454.1 - 0.047 13.2 0.1 0.14 11.7 0.1 1.7 2 0 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family ISG65-75 PF11727.8 CDJ96454.1 - 0.077 12.2 3.8 0.11 11.7 3.8 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Atg14 PF10186.9 CDJ96454.1 - 0.2 10.7 3.5 0.28 10.2 3.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4239 PF14023.6 CDJ96454.1 - 0.31 10.8 0.7 0.55 9.9 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) RVT_1 PF00078.27 CDJ96455.1 - 6.8e-09 35.6 0.0 8.9e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7TM_GPCR_Srx PF10328.9 CDJ96456.1 - 1.2e-56 192.3 27.4 1.5e-56 192.0 27.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 CDJ96456.1 - 0.00044 19.7 12.7 0.00044 19.7 12.7 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srbc PF10316.9 CDJ96456.1 - 0.0025 17.4 12.4 0.0025 17.4 12.4 2.5 2 2 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7tm_1 PF00001.21 CDJ96456.1 - 0.011 15.1 17.4 0.016 14.6 17.4 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) TssO PF17561.2 CDJ96456.1 - 4.7 7.3 6.1 8 6.6 0.9 2.5 2 0 0 2 2 2 0 Type VI secretion system, TssO Y_phosphatase PF00102.27 CDJ96457.1 - 8e-26 91.0 0.0 1.3e-25 90.3 0.0 1.4 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ96457.1 - 8.8e-05 22.3 0.2 0.00015 21.6 0.1 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDJ96457.1 - 0.001 19.1 0.1 0.0013 18.7 0.1 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family UDPGT PF00201.18 CDJ96458.1 - 0.013 14.3 0.0 0.014 14.2 0.0 1.0 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_4 PF13439.6 CDJ96458.1 - 0.045 13.8 0.0 0.17 11.9 0.0 1.8 1 1 0 1 1 1 0 Glycosyltransferase Family 4 DUF3053 PF11254.8 CDJ96459.1 - 0.0062 16.1 0.9 0.0062 16.1 0.9 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3053) DUF4826 PF16108.5 CDJ96459.1 - 0.089 13.0 0.4 3 8.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4826) CSN7a_helixI PF18392.1 CDJ96459.1 - 0.29 11.1 3.0 6.7 6.7 0.1 3.5 3 0 0 3 3 3 0 COP9 signalosome complex subunit 7a helix I domain TM2 PF05154.16 CDJ96460.1 - 1.2e-12 47.9 7.2 2e-12 47.2 7.2 1.3 1 0 0 1 1 1 1 TM2 domain DUF4801 PF16059.5 CDJ96460.1 - 0.04 13.9 3.5 0.04 13.9 3.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4801) Ribosomal_S19e PF01090.19 CDJ96461.1 - 1.3e-56 190.1 0.4 1.4e-56 190.0 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e IF3_C PF00707.22 CDJ96461.1 - 0.044 13.7 1.4 3.2 7.8 0.3 2.8 2 1 1 3 3 3 0 Translation initiation factor IF-3, C-terminal domain GntR PF00392.21 CDJ96461.1 - 0.047 13.3 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family BRCT_3 PF18428.1 CDJ96462.1 - 1.2e-22 79.9 0.1 1.8e-17 63.3 0.0 2.9 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain BRCT PF00533.26 CDJ96462.1 - 8.9e-09 35.6 0.2 4.1e-07 30.3 0.0 3.0 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CDJ96462.1 - 1.8e-07 31.5 0.0 3.4e-06 27.4 0.0 2.8 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 CDJ96462.1 - 1.7e-06 27.8 0.0 9e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain Tudor_3 PF18115.1 CDJ96462.1 - 5.7e-05 22.9 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain PTCB-BRCT PF12738.7 CDJ96462.1 - 0.038 14.0 0.0 13 5.9 0.0 3.2 2 0 0 2 2 2 0 twin BRCT domain Aldo_ket_red PF00248.21 CDJ96464.1 - 1.5e-49 168.8 0.0 2e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1647 PF07801.11 CDJ96465.1 - 6.8e-32 110.1 0.3 1.8e-31 108.8 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) L27 PF02828.16 CDJ96465.1 - 0.18 11.6 0.4 0.52 10.1 0.1 1.9 2 0 0 2 2 2 0 L27 domain Aldo_ket_red PF00248.21 CDJ96466.1 - 1.7e-50 171.9 0.0 2.1e-50 171.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 CDJ96467.1 - 3.2e-102 341.7 0.2 1.3e-52 178.8 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family BMC PF00936.19 CDJ96467.1 - 0.0039 17.2 0.0 2.8 8.0 0.0 3.6 4 0 0 4 4 4 1 BMC domain DUF3005 PF11448.8 CDJ96467.1 - 0.0061 16.6 0.0 2.1 8.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3005) PAS_3 PF08447.12 CDJ96467.1 - 0.011 16.0 0.1 5.6 7.3 0.0 2.5 2 0 0 2 2 2 0 PAS fold Pestivirus_E2 PF16329.5 CDJ96467.1 - 0.022 13.6 0.3 2.5 6.9 0.0 3.0 4 0 0 4 4 4 0 Pestivirus envelope glycoprotein E2 DUF4342 PF14242.6 CDJ96467.1 - 0.034 14.1 0.3 14 5.8 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4342) DNA_meth_N PF18284.1 CDJ96467.1 - 0.059 13.3 0.0 14 5.6 0.0 2.5 2 0 0 2 2 2 0 DNA methylase N-terminal domain MMR_HSR1_Xtn PF16897.5 CDJ96467.1 - 0.097 12.7 0.0 16 5.5 0.0 3.9 5 0 0 5 5 5 0 C-terminal region of MMR_HSR1 domain DUF3019 PF11456.8 CDJ96467.1 - 0.1 13.1 2.6 9 6.9 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3019) PUA PF01472.20 CDJ96467.1 - 0.14 12.2 0.1 20 5.2 0.0 2.6 2 0 0 2 2 2 0 PUA domain SURF1 PF02104.15 CDJ96467.1 - 0.14 12.4 0.0 18 5.6 0.0 2.3 2 0 0 2 2 2 0 SURF1 family Nore1-SARAH PF16517.5 CDJ96467.1 - 0.26 11.2 0.7 27 4.8 0.0 2.5 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Aldo_ket_red PF00248.21 CDJ96468.1 - 1.2e-17 64.0 0.0 5.8e-08 32.3 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Metallophos PF00149.28 CDJ96469.1 - 8.1e-09 36.3 0.1 1.2e-08 35.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDJ96469.1 - 0.00099 19.3 0.0 0.0014 18.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2975 PF11188.8 CDJ96469.1 - 3.3 7.6 14.6 0.81 9.6 2.9 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF2975) GCV_T PF01571.21 CDJ96470.1 - 1e-30 107.0 0.0 1.3e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 CDJ96470.1 - 3.3e-08 33.3 0.0 1.6e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 CDJ96470.1 - 0.024 14.8 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 Sarcosine oxidase, gamma subunit family HTH_23 PF13384.6 CDJ96472.1 - 6.5e-10 38.5 6.7 8e-09 35.1 0.3 3.0 3 0 0 3 3 2 1 Homeodomain-like domain HTH_29 PF13551.6 CDJ96472.1 - 4.1e-09 36.3 3.0 6.8e-08 32.4 0.3 2.9 3 1 0 3 3 2 1 Winged helix-turn helix DDE_3 PF13358.6 CDJ96472.1 - 1.8e-06 27.8 0.0 5.6e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_28 PF13518.6 CDJ96472.1 - 2.5e-06 27.5 9.1 2.9e-05 24.1 1.0 3.2 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_11 PF08279.12 CDJ96472.1 - 4.9e-05 23.2 1.2 0.0005 19.9 0.0 2.4 2 0 0 2 2 2 1 HTH domain HTH_32 PF13565.6 CDJ96472.1 - 9.1e-05 23.0 10.4 9.2e-05 23.0 3.8 3.5 3 2 1 4 4 4 1 Homeodomain-like domain HTH_Tnp_1 PF01527.20 CDJ96472.1 - 0.00021 21.6 1.4 0.12 12.7 0.5 2.4 1 1 1 2 2 2 2 Transposase HTH_Tnp_IS630 PF01710.16 CDJ96472.1 - 0.00045 20.3 2.0 0.00079 19.5 2.0 1.3 1 0 0 1 1 1 1 Transposase HTH_38 PF13936.6 CDJ96472.1 - 0.00052 19.7 1.3 0.00052 19.7 1.3 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain Sulfotransfer_1 PF00685.27 CDJ96472.1 - 0.00066 19.2 0.4 0.0011 18.5 0.4 1.4 1 0 0 1 1 1 1 Sulfotransferase domain TnsD PF15978.5 CDJ96472.1 - 0.0009 18.3 2.8 0.011 14.8 2.1 2.1 1 1 1 2 2 2 1 Tn7-like transposition protein D MarR PF01047.22 CDJ96472.1 - 0.0024 17.7 0.1 0.29 11.1 0.1 2.3 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 CDJ96472.1 - 0.0047 16.8 0.8 1.5 8.8 0.0 2.6 2 0 0 2 2 2 1 MarR family HTH_Tnp_Tc3_2 PF01498.18 CDJ96472.1 - 0.0056 16.9 6.2 0.0056 16.9 6.2 2.7 3 0 0 3 3 3 1 Transposase Terminase_5 PF06056.12 CDJ96472.1 - 0.0086 15.9 0.2 0.066 13.1 0.0 2.5 2 0 0 2 2 2 1 Putative ATPase subunit of terminase (gpP-like) HTH_6 PF01418.17 CDJ96472.1 - 0.013 15.4 0.0 0.057 13.4 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family TrmB PF01978.19 CDJ96472.1 - 0.016 15.1 0.1 0.31 10.9 0.0 2.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Exo_endo_phos PF03372.23 CDJ96472.1 - 0.037 13.5 0.0 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family Mga PF05043.13 CDJ96472.1 - 0.051 14.2 0.3 9.6 6.9 0.0 2.7 3 0 0 3 3 2 0 Mga helix-turn-helix domain PAX PF00292.18 CDJ96472.1 - 0.055 13.4 0.5 0.096 12.6 0.5 1.3 1 0 0 1 1 1 0 'Paired box' domain HTH_IclR PF09339.10 CDJ96472.1 - 0.066 13.0 0.1 2.8 7.8 0.0 2.4 2 0 0 2 2 2 0 IclR helix-turn-helix domain DUF746 PF05344.11 CDJ96472.1 - 0.076 12.9 0.0 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) Phage_AlpA PF05930.12 CDJ96472.1 - 0.11 12.4 0.1 0.33 10.8 0.1 1.8 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) Rrf2 PF02082.20 CDJ96472.1 - 0.11 12.8 0.1 17 5.9 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator HTH_24 PF13412.6 CDJ96472.1 - 0.28 10.8 2.2 10 5.8 0.5 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_17 PF12728.7 CDJ96472.1 - 1.1 9.5 6.6 9.3 6.5 0.1 3.5 4 0 0 4 4 4 0 Helix-turn-helix domain TauE PF01925.19 CDJ96473.1 - 3.4e-16 59.6 20.0 3.4e-16 59.6 20.0 1.8 1 1 1 2 2 2 1 Sulfite exporter TauE/SafE TauE PF01925.19 CDJ96474.1 - 1.2e-17 64.3 19.4 1.8e-17 63.8 19.4 1.2 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE CPP1-like PF11833.8 CDJ96474.1 - 0.041 13.6 2.8 0.039 13.6 0.7 1.9 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Acetyltransf_18 PF18014.1 CDJ96475.1 - 0.00066 19.5 0.0 0.0018 18.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Defensin_beta PF00711.19 CDJ96477.1 - 0.022 14.8 0.8 7.9 6.6 0.2 2.5 2 0 0 2 2 2 0 Beta defensin UCH PF00443.29 CDJ96478.1 - 1.5e-72 244.2 0.0 2e-72 243.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ96478.1 - 1.2e-11 44.8 2.5 4.6e-08 33.0 0.1 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 CDJ96478.1 - 4.4e-08 33.6 0.0 1.4e-07 32.0 0.0 2.0 1 0 0 1 1 1 1 DUSP domain NFRKB_winged PF14465.6 CDJ96478.1 - 0.0047 17.1 0.2 0.036 14.3 0.1 2.3 2 0 0 2 2 2 1 NFRKB Winged Helix-like Knl1_RWD_C PF18210.1 CDJ96478.1 - 0.027 14.9 0.1 0.35 11.4 0.1 2.6 3 0 0 3 3 3 0 Knl1 RWD C-terminal domain zf-C6H2 PF15801.5 CDJ96478.1 - 0.22 11.9 3.3 1.1 9.6 0.7 2.5 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-MIZ PF02891.20 CDJ96478.1 - 1 9.2 4.2 1.1 9.1 0.4 2.6 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger PHD PF00628.29 CDJ96478.1 - 3.6 7.5 4.8 0.86 9.5 1.0 1.9 2 0 0 2 2 2 0 PHD-finger Nodulin_late PF07127.11 CDJ96479.1 - 2.2 8.7 0.0 2.2 8.7 0.0 3.1 2 1 1 3 3 3 0 Late nodulin protein EGF_2 PF07974.13 CDJ96479.1 - 2.8 8.4 13.6 8 6.9 13.6 1.8 1 0 0 1 1 1 0 EGF-like domain RT_RNaseH PF17917.1 CDJ96480.1 - 6.9e-32 109.9 0.0 1.5e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ96480.1 - 1e-31 110.2 0.1 1.6e-31 109.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDJ96480.1 - 1.6e-30 105.0 0.0 3.2e-30 104.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 CDJ96481.1 - 4.4e-05 24.0 0.2 0.00012 22.6 0.2 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 CDJ96481.1 - 0.00018 21.4 3.3 0.00034 20.5 3.3 1.5 1 0 0 1 1 1 1 Zinc knuckle FUSC PF04632.12 CDJ96481.1 - 1.8 7.0 3.7 2.3 6.7 3.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family MAGE_N PF12440.8 CDJ96482.1 - 7.8 7.2 11.9 27 5.5 11.9 1.9 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal PH_9 PF15410.6 CDJ96483.1 - 3.6e-35 120.9 0.0 7.4e-35 119.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Sec7 PF01369.20 CDJ96483.1 - 9.1e-33 113.5 0.2 2.4e-32 112.1 0.0 1.7 2 0 0 2 2 2 1 Sec7 domain PH PF00169.29 CDJ96483.1 - 2.1e-07 31.4 0.0 5e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 CDJ96483.1 - 0.017 14.9 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Collectrin PF16959.5 CDJ96484.1 - 0.48 10.2 4.2 1.1 9.0 0.5 2.1 1 1 1 2 2 2 0 Renal amino acid transporter DUF167 PF02594.16 CDJ96487.1 - 8.3e-19 67.5 0.0 1.3e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 PreAtp-grasp PF18604.1 CDJ96487.1 - 0.06 13.0 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 Pre ATP-grasp domain CRAL_TRIO_2 PF13716.6 CDJ96488.1 - 6.9e-42 142.9 1.6 2.1e-41 141.3 0.4 2.1 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 CDJ96488.1 - 9.9e-38 129.3 0.2 2.8e-37 127.9 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain CRAL_TRIO PF00650.20 CDJ96488.1 - 3.6e-09 36.5 0.5 3.6e-09 36.5 0.5 1.8 2 1 0 2 2 2 1 CRAL/TRIO domain TPR_1 PF00515.28 CDJ96489.1 - 1.5e-08 34.1 7.2 4.1e-05 23.2 0.6 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ96489.1 - 2.1e-07 30.5 11.7 5.1e-05 23.1 0.1 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ96489.1 - 3.5e-07 29.9 3.2 0.00013 21.9 0.1 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ96489.1 - 2.2e-06 28.0 0.1 0.56 11.2 0.0 4.7 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ96489.1 - 1.3e-05 24.7 0.5 0.46 10.2 0.0 3.8 2 1 1 3 3 3 2 TPR repeat TPR_12 PF13424.6 CDJ96489.1 - 7.3e-05 23.0 4.1 0.00047 20.4 0.1 3.6 4 2 1 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ96489.1 - 0.00019 21.3 1.3 0.0014 18.5 0.0 3.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ96489.1 - 0.00082 19.8 0.0 0.4 11.2 0.0 3.8 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ96489.1 - 0.0039 17.7 0.4 0.023 15.3 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ96489.1 - 0.0045 17.3 0.0 20 5.9 0.0 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ96489.1 - 0.0069 16.2 1.7 0.29 11.0 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.18 CDJ96489.1 - 0.015 15.4 5.6 1.1 9.3 1.3 3.7 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain SNAP PF14938.6 CDJ96489.1 - 0.018 14.5 1.3 0.025 14.0 0.4 1.7 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP RPN7 PF10602.9 CDJ96489.1 - 0.068 12.9 0.1 0.48 10.1 0.1 2.1 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_16 PF13432.6 CDJ96489.1 - 0.11 13.1 0.4 4 8.2 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Phage_holin_2_1 PF04971.12 CDJ96490.1 - 1 9.4 3.9 0.68 10.0 1.4 1.9 2 0 0 2 2 2 0 Bacteriophage P21 holin S Tuberin PF03542.16 CDJ96491.1 - 0.088 11.9 0.0 0.2 10.7 0.0 1.6 1 0 0 1 1 1 0 Tuberin DUF1356 PF07092.12 CDJ96492.1 - 8.9e-39 133.1 1.7 1.2e-38 132.7 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) Anti-TRAP PF15777.5 CDJ96492.1 - 0.0015 18.5 0.0 0.0027 17.7 0.0 1.3 1 0 0 1 1 1 1 Tryptophan RNA-binding attenuator protein inhibitory protein VirB8 PF04335.13 CDJ96492.1 - 0.011 15.6 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 0 VirB8 protein DUF5351 PF17302.2 CDJ96492.1 - 0.021 15.0 0.4 0.045 13.9 0.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5351) SH2 PF00017.24 CDJ96493.1 - 8.2e-25 86.7 0.0 7e-13 48.5 0.0 2.7 3 0 0 3 3 3 2 SH2 domain CCDC53 PF10152.9 CDJ96493.1 - 0.17 12.3 1.8 0.28 11.6 1.8 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF489 PF04356.12 CDJ96493.1 - 0.36 10.8 2.8 14 5.6 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF489) DUF2524 PF10732.9 CDJ96493.1 - 0.4 11.0 5.3 0.59 10.5 0.2 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF2524) KASH_CCD PF14662.6 CDJ96493.1 - 0.67 9.7 8.6 1.2 9.0 8.6 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Syntaxin-6_N PF09177.11 CDJ96493.1 - 1.2 9.7 4.6 0.6 10.7 1.6 2.0 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Tropomyosin_1 PF12718.7 CDJ96493.1 - 2.3 8.4 10.3 1.9 8.6 8.2 1.8 1 1 1 2 2 2 0 Tropomyosin like YscO PF07321.12 CDJ96493.1 - 2.9 7.8 12.3 0.76 9.7 3.8 2.2 1 1 1 2 2 2 0 Type III secretion protein YscO z-alpha PF02295.17 CDJ96494.1 - 0.0019 18.2 0.2 0.0028 17.7 0.2 1.2 1 0 0 1 1 1 1 Adenosine deaminase z-alpha domain Osmo_CC PF08946.10 CDJ96494.1 - 0.053 13.8 1.4 0.92 9.8 0.3 2.2 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DUF4077 PF13295.6 CDJ96495.1 - 0.16 11.9 1.3 0.19 11.6 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4077) DUF973 PF06157.11 CDJ96495.1 - 2.2 7.2 4.3 2.8 6.9 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DPM2 PF07297.12 CDJ96495.1 - 2.3 8.6 4.5 1.4 9.3 0.8 2.0 1 1 1 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) ATP-synt_ab PF00006.25 CDJ96497.1 - 3.3e-68 229.5 0.0 4.6e-68 229.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CDJ96497.1 - 3.5e-14 53.1 0.1 6.4e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 CDJ96497.1 - 0.014 15.5 0.1 0.027 14.6 0.1 1.5 1 0 0 1 1 1 0 HAS barrel domain DUF3762 PF12591.8 CDJ96497.1 - 0.17 12.1 0.0 0.37 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) Adenylate_cycl PF01295.18 CDJ96497.1 - 0.25 9.9 0.0 0.34 9.5 0.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase, class-I DUF1455 PF07306.11 CDJ96499.1 - 0.031 14.2 0.6 0.21 11.6 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1455) Lectin_C PF00059.21 CDJ96500.1 - 4.2e-07 30.7 0.1 8.1e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 Lectin C-type domain VWA PF00092.28 CDJ96500.1 - 0.0099 16.1 0.0 0.014 15.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain RPT PF13446.6 CDJ96501.1 - 0.1 12.5 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 A repeated domain in UCH-protein zf-C4 PF00105.18 CDJ96505.1 - 9.9e-20 70.8 16.4 3.4e-19 69.1 16.4 2.0 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ96505.1 - 9e-17 61.3 0.7 1.8e-16 60.4 0.7 1.6 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Anti-TRAP PF15777.5 CDJ96505.1 - 0.21 11.6 2.6 5.6 7.0 0.9 2.7 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Frag1 PF10277.9 CDJ96506.1 - 3.1e-31 108.6 17.8 3.9e-31 108.3 17.8 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family BORA_N PF15280.6 CDJ96507.1 - 5.8e-38 130.8 2.1 1e-37 130.0 2.1 1.3 1 0 0 1 1 1 1 Protein aurora borealis N-terminus Trm112p PF03966.16 CDJ96508.1 - 2.2e-13 50.5 0.0 3.1e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Trm112p-like protein S1-like PF14444.6 CDJ96508.1 - 0.16 11.9 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 S1-like ELO PF01151.18 CDJ96509.1 - 1.8e-67 227.5 18.1 2.1e-67 227.3 18.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Asp PF00026.23 CDJ96510.1 - 5.1e-88 295.5 1.4 6.1e-88 295.3 1.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ96510.1 - 1.2e-11 45.2 5.9 9.8e-11 42.2 5.5 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ96510.1 - 3.8e-05 23.5 0.1 0.00054 19.8 0.1 2.5 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CDJ96510.1 - 0.0031 18.1 0.0 0.67 10.6 0.0 3.0 3 0 0 3 3 3 1 Aspartyl protease Hormone_recep PF00104.30 CDJ96511.1 - 5.4e-13 49.0 0.0 1.2e-12 47.8 0.0 1.5 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor RRN3 PF05327.11 CDJ96512.1 - 0.12 10.9 3.6 0.13 10.8 3.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4598 PF15370.6 CDJ96512.1 - 0.19 12.2 11.5 24 5.5 11.0 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4598) UBX PF00789.20 CDJ96513.1 - 1.9e-07 31.2 0.0 2.5e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 UBX domain Glyco_hydro_18 PF00704.28 CDJ96514.1 - 1.3e-42 146.6 4.3 4.4e-34 118.6 1.1 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 CDJ96514.1 - 9.9e-05 22.7 12.4 9.9e-05 22.7 12.4 1.8 2 0 0 2 2 2 1 Chitin recognition protein Moulting_cycle PF04870.16 CDJ96515.1 - 1.1e-08 34.7 0.0 1.4e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Moulting cycle Pro-kuma_activ PF09286.11 CDJ96515.1 - 0.021 15.1 0.0 0.11 12.7 0.0 1.8 2 0 0 2 2 2 0 Pro-kumamolisin, activation domain BON PF04972.17 CDJ96515.1 - 0.11 12.9 0.9 0.39 11.0 0.2 2.0 2 0 0 2 2 2 0 BON domain PMP22_Claudin PF00822.20 CDJ96516.1 - 9.9e-10 38.5 6.4 2.3e-09 37.3 6.4 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 CDJ96516.1 - 1.7e-08 34.4 13.5 2.1e-07 30.9 13.2 2.3 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.12 CDJ96516.1 - 9.2e-06 25.4 15.5 0.00031 20.4 15.5 2.0 1 1 0 1 1 1 1 SUR7/PalI family TMEM37 PF15108.6 CDJ96516.1 - 0.00015 21.7 0.8 0.00023 21.1 0.8 1.3 1 0 0 1 1 1 1 Voltage-dependent calcium channel gamma-like subunit protein family L_HMGIC_fpl PF10242.9 CDJ96516.1 - 0.00034 20.9 2.8 0.00053 20.2 2.7 1.4 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_3 PF06653.11 CDJ96516.1 - 0.0076 16.2 7.9 0.017 15.1 7.9 1.5 1 1 0 1 1 1 1 Tight junction protein, Claudin-like Amastin PF07344.11 CDJ96516.1 - 0.0079 16.0 0.9 0.0079 16.0 0.9 2.1 2 0 0 2 2 2 1 Amastin surface glycoprotein Atthog PF18800.1 CDJ96516.1 - 0.02 14.8 1.1 0.02 14.8 1.1 2.2 2 0 0 2 2 2 0 Attenuator of Hedgehog Tetraspanin PF00335.20 CDJ96516.1 - 0.49 10.1 6.3 0.7 9.6 5.6 1.5 1 1 0 1 1 1 0 Tetraspanin family DUF3413 PF11893.8 CDJ96516.1 - 2.8 7.1 7.4 0.31 10.2 2.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) Clc-like PF07062.12 CDJ96516.1 - 3.9 6.9 10.8 0.18 11.3 1.5 2.3 2 1 0 2 2 2 0 Clc-like Peptidase_M10 PF00413.24 CDJ96518.1 - 6.9e-42 143.0 3.4 1e-41 142.5 3.4 1.2 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.18 CDJ96518.1 - 4.8e-06 26.7 0.0 1.8e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Reprolysin_4 PF13583.6 CDJ96518.1 - 0.0044 16.7 0.0 0.0079 15.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 CDJ96518.1 - 0.0062 15.8 0.1 0.023 13.9 0.0 1.8 2 0 0 2 2 2 1 Met-zincin Reprolysin_3 PF13582.6 CDJ96518.1 - 0.0081 16.7 0.1 0.02 15.4 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 CDJ96518.1 - 0.023 14.7 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 Reprolysin_5 PF13688.6 CDJ96518.1 - 0.04 14.0 0.0 0.084 13.0 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 CDJ96518.1 - 0.042 12.8 0.1 0.07 12.1 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M64 PF09471.10 CDJ96518.1 - 0.14 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 IgA Peptidase M64 Astacin PF01400.24 CDJ96518.1 - 0.16 11.5 0.2 0.46 10.1 0.2 1.7 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M57 PF12388.8 CDJ96518.1 - 0.2 11.3 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase TAP42 PF04177.12 CDJ96519.1 - 1.2e-69 235.0 0.5 1.2e-69 235.0 0.5 1.9 2 0 0 2 2 2 1 TAP42-like family RNA_GG_bind PF10258.9 CDJ96519.1 - 4.3e-25 87.6 0.1 9.7e-25 86.4 0.1 1.6 1 0 0 1 1 1 1 PHAX RNA-binding domain ACBP PF00887.19 CDJ96519.1 - 1.9e-08 34.4 0.4 1.9e-08 34.4 0.4 2.7 2 0 0 2 2 2 1 Acyl CoA binding protein Sedlin_N PF04628.13 CDJ96520.1 - 4.7e-23 81.7 0.3 5.5e-23 81.5 0.3 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 CDJ96520.1 - 0.00016 21.6 0.0 0.00022 21.2 0.0 1.3 1 1 0 1 1 1 1 Sybindin-like family Fe_hyd_lg_C PF02906.14 CDJ96521.1 - 2.6e-13 50.2 1.1 2.8e-13 50.1 0.1 1.5 2 0 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain DUF2913 PF11140.8 CDJ96521.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) WD40 PF00400.32 CDJ96522.1 - 2.6e-14 53.4 5.4 0.00023 21.9 0.6 4.2 3 0 0 3 3 3 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 CDJ96522.1 - 1.1e-13 51.2 0.1 3.4e-12 46.4 0.0 2.6 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ubiquitin PF00240.23 CDJ96522.1 - 4e-10 39.3 0.0 8e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family ANAPC4_WD40 PF12894.7 CDJ96522.1 - 6.9e-07 29.5 0.3 0.018 15.3 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDJ96522.1 - 0.0071 16.2 0.0 0.044 13.6 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Ubiquitin_2 PF14560.6 CDJ96522.1 - 0.078 13.4 2.3 0.089 13.3 0.0 2.3 3 0 0 3 3 3 0 Ubiquitin-like domain FAM176 PF14851.6 CDJ96522.1 - 0.14 11.8 2.0 2.9 7.5 0.1 2.4 2 0 0 2 2 2 0 FAM176 family DB PF01682.19 CDJ96523.1 - 2.9e-26 91.6 13.3 6.2e-26 90.6 13.3 1.6 1 0 0 1 1 1 1 DB module DB PF01682.19 CDJ96525.1 - 1e-23 83.4 10.9 1e-23 83.4 10.9 1.5 2 0 0 2 2 2 1 DB module FH2 PF02181.23 CDJ96526.1 - 1.3e-70 238.4 14.1 2.5e-70 237.5 14.1 1.5 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 CDJ96526.1 - 2.6e-35 121.8 0.1 3.7e-34 118.1 0.0 2.7 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 CDJ96526.1 - 0.0062 16.1 0.1 0.032 13.8 0.0 2.2 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain DUF1844 PF08899.11 CDJ96526.1 - 0.44 10.9 4.5 0.23 11.8 0.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1844) zf-C3Hc3H PF13891.6 CDJ96527.1 - 6.7e-07 29.6 10.1 9.8e-06 25.9 3.6 2.5 2 0 0 2 2 2 2 Potential DNA-binding domain PRAI PF00697.22 CDJ96527.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase HEAT PF02985.22 CDJ96528.1 - 0.00075 19.5 0.8 7 7.2 0.0 5.2 4 0 0 4 4 4 1 HEAT repeat DUF150_C PF17384.2 CDJ96528.1 - 0.032 14.4 0.1 0.087 13.0 0.1 1.7 1 0 0 1 1 1 0 RimP C-terminal SH3 domain Cnd1 PF12717.7 CDJ96528.1 - 0.19 11.8 10.3 0.072 13.1 0.9 4.5 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 MPC PF03650.13 CDJ96529.1 - 7.6e-35 119.4 0.2 9.8e-35 119.0 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DUF3338 PF11819.8 CDJ96530.1 - 5.5e-29 100.9 4.8 1e-28 100.0 4.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3338) TFIIB PF00382.19 CDJ96530.1 - 0.13 12.3 0.5 0.67 10.0 0.2 2.0 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Pkinase_Tyr PF07714.17 CDJ96532.1 - 1.3e-85 286.9 0.0 1.7e-85 286.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ96532.1 - 3.1e-39 135.0 0.0 4.7e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.16 CDJ96532.1 - 3.7e-19 68.6 0.0 6.3e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Kringle PF00051.18 CDJ96532.1 - 1.3e-17 63.9 7.4 3.9e-17 62.3 7.4 1.9 1 0 0 1 1 1 1 Kringle domain Ig_3 PF13927.6 CDJ96532.1 - 9.3e-13 48.6 0.0 2.4e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CDJ96532.1 - 2.6e-10 40.4 0.0 4.6e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CDJ96532.1 - 8.1e-09 35.7 0.1 1.7e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Fz PF01392.22 CDJ96532.1 - 1.1e-06 29.2 3.7 1.1e-06 29.2 3.7 1.8 2 0 0 2 2 1 1 Fz domain Kinase-like PF14531.6 CDJ96532.1 - 0.0015 17.9 0.0 0.0049 16.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Shisa PF13908.6 CDJ96532.1 - 0.0025 18.1 1.0 0.0042 17.3 0.0 1.9 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator Mucin PF01456.17 CDJ96532.1 - 0.0053 16.8 1.0 0.024 14.6 0.7 2.1 2 0 0 2 2 2 1 Mucin-like glycoprotein Orthoreo_P10 PF07204.11 CDJ96532.1 - 0.0055 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 V-set PF07686.17 CDJ96532.1 - 0.0091 16.2 0.1 0.088 13.0 0.1 2.4 1 1 0 1 1 1 1 Immunoglobulin V-set domain RCR PF12273.8 CDJ96532.1 - 0.01 16.5 0.7 0.055 14.1 0.1 2.5 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Ig_5 PF16681.5 CDJ96532.1 - 0.052 14.0 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Syndecan PF01034.20 CDJ96532.1 - 0.19 11.6 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Tweety PF04906.13 CDJ96532.1 - 0.45 9.1 4.1 0.11 11.1 0.4 1.7 2 0 0 2 2 2 0 Tweety ORC2 PF04084.14 CDJ96533.1 - 2.6e-57 194.2 0.6 2.6e-57 194.2 0.6 1.7 2 0 0 2 2 2 1 Origin recognition complex subunit 2 Clat_adaptor_s PF01217.20 CDJ96533.1 - 2.4e-27 95.6 0.5 4.7e-27 94.7 0.5 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RYDR_ITPR PF01365.21 CDJ96533.1 - 0.15 11.5 3.8 1.2 8.5 0.2 3.0 3 0 0 3 3 3 0 RIH domain PAN_1 PF00024.26 CDJ96536.1 - 7.8e-05 22.6 2.2 0.00018 21.4 2.2 1.6 1 0 0 1 1 1 1 PAN domain zf_CopZ PF18423.1 CDJ96536.1 - 0.014 15.3 1.3 0.014 15.3 1.3 1.6 2 0 0 2 2 2 0 Zinc binding domain Arena_ncap_C PF17290.2 CDJ96536.1 - 0.022 14.1 0.1 0.034 13.5 0.1 1.2 1 0 0 1 1 1 0 Arenavirus nucleocapsid C-terminal domain TAFH PF07531.14 CDJ96537.1 - 0.0063 16.6 0.1 0.23 11.6 0.0 2.2 2 0 0 2 2 2 1 NHR1 homology to TAF ATP-cone PF03477.16 CDJ96537.1 - 0.034 14.7 0.0 0.06 13.9 0.0 1.4 1 0 0 1 1 1 0 ATP cone domain SapB_2 PF03489.17 CDJ96537.1 - 0.14 12.3 2.3 0.14 12.2 1.0 1.8 2 0 0 2 2 2 0 Saposin-like type B, region 2 SinI PF08671.10 CDJ96537.1 - 0.18 11.7 0.1 0.39 10.6 0.1 1.5 1 0 0 1 1 1 0 Anti-repressor SinI HscB_4_cys PF18256.1 CDJ96538.1 - 0.13 12.1 0.2 0.13 12.1 0.2 1.7 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif PAN_1 PF00024.26 CDJ96540.1 - 0.0025 17.8 1.0 0.0054 16.7 1.0 1.5 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 CDJ96540.1 - 0.17 11.7 0.1 0.35 10.7 0.1 1.4 1 0 0 1 1 1 0 PAN-like domain Sre PF03125.18 CDJ96541.1 - 3.7e-21 75.7 7.5 4.3e-21 75.5 7.5 1.1 1 0 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor 7TM_GPCR_Srab PF10292.9 CDJ96541.1 - 4e-06 26.0 3.7 0.00027 20.0 3.6 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7tm_1 PF00001.21 CDJ96541.1 - 1.7 7.9 7.6 3 7.1 7.6 1.4 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Glyco_hydro_38N PF01074.22 CDJ96542.1 - 8.4e-87 291.2 0.6 9.6e-87 291.0 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain PNP_UDP_1 PF01048.20 CDJ96543.1 - 3.7e-48 163.8 0.2 4.4e-48 163.6 0.2 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Prefoldin_2 PF01920.20 CDJ96545.1 - 0.00083 19.3 3.1 0.72 9.8 0.1 4.0 4 0 0 4 4 4 1 Prefoldin subunit BLOC1_2 PF10046.9 CDJ96545.1 - 0.0026 18.0 8.2 2.6 8.4 0.1 3.6 3 1 1 4 4 4 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prominin PF05478.11 CDJ96545.1 - 0.0045 15.0 1.0 0.0054 14.8 0.1 1.4 2 0 0 2 2 2 1 Prominin Apolipoprotein PF01442.18 CDJ96545.1 - 0.0054 16.6 3.8 2.5 7.9 2.7 2.8 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain Tmemb_cc2 PF10267.9 CDJ96545.1 - 0.0088 15.2 0.9 0.056 12.6 0.4 2.0 2 0 0 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein Sec34 PF04136.15 CDJ96545.1 - 0.011 15.6 5.9 0.12 12.3 0.3 3.1 2 1 1 3 3 3 0 Sec34-like family Prefoldin PF02996.17 CDJ96545.1 - 0.012 15.6 14.0 0.13 12.2 1.4 4.3 4 0 0 4 4 4 0 Prefoldin subunit Laminin_II PF06009.12 CDJ96545.1 - 0.019 15.0 6.3 3.3 7.7 0.3 3.1 3 0 0 3 3 3 0 Laminin Domain II UPF0184 PF03670.13 CDJ96545.1 - 0.02 15.3 0.1 1 9.8 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) Dynactin_p22 PF07426.11 CDJ96545.1 - 0.034 14.0 1.5 0.56 10.1 0.1 2.9 3 0 0 3 3 3 0 Dynactin subunit p22 DUF4140 PF13600.6 CDJ96545.1 - 0.058 13.8 5.0 1.1 9.7 0.0 3.2 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) FlaC_arch PF05377.11 CDJ96545.1 - 0.067 13.6 0.3 0.067 13.6 0.3 3.5 4 1 1 5 5 3 0 Flagella accessory protein C (FlaC) Sec3_C_2 PF15278.6 CDJ96545.1 - 0.082 13.3 2.8 0.17 12.3 0.2 2.6 2 1 0 2 2 2 0 Sec3 exocyst complex subunit PA28_beta PF02252.18 CDJ96545.1 - 0.092 12.4 1.8 5.1 6.8 0.0 3.2 2 2 1 3 3 3 0 Proteasome activator pa28 beta subunit GARP PF16731.5 CDJ96545.1 - 0.11 12.1 8.3 5.7 6.6 0.1 3.2 3 0 0 3 3 3 0 Glutamic acid/alanine-rich protein of Trypanosoma TPR_MLP1_2 PF07926.12 CDJ96545.1 - 0.22 11.6 9.3 1.7 8.7 0.2 3.3 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Spc24 PF08286.11 CDJ96545.1 - 0.24 11.6 7.5 0.59 10.4 0.1 3.4 3 1 1 4 4 3 0 Spc24 subunit of Ndc80 Alanine_zipper PF11839.8 CDJ96545.1 - 0.24 11.8 11.2 7.3 7.0 0.1 3.5 3 0 0 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein T4SS PF07996.11 CDJ96545.1 - 0.32 11.4 8.6 2.4 8.5 0.2 2.7 2 1 0 2 2 2 0 Type IV secretion system proteins TMP_2 PF06791.13 CDJ96545.1 - 0.33 10.6 5.8 7.3 6.2 0.1 2.6 2 1 0 2 2 2 0 Prophage tail length tape measure protein SlyX PF04102.12 CDJ96545.1 - 0.36 11.5 1.3 12 6.6 0.0 2.8 3 0 0 3 3 2 0 SlyX DUF883 PF05957.13 CDJ96545.1 - 0.37 11.4 6.5 14 6.3 0.5 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 CDJ96545.1 - 0.45 11.1 20.1 80 3.9 7.6 4.2 2 2 0 2 2 2 0 YtxH-like protein WXG100 PF06013.12 CDJ96545.1 - 0.69 10.2 8.4 6.6 7.1 0.7 3.9 2 1 0 3 3 3 0 Proteins of 100 residues with WXG Fib_alpha PF08702.10 CDJ96545.1 - 0.89 9.7 6.4 2.4 8.3 2.3 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF5339 PF17274.2 CDJ96545.1 - 1.1 10.1 4.4 4.1 8.3 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5339) DivIVA PF05103.13 CDJ96545.1 - 1.4 9.0 11.6 0.25 11.4 5.4 2.5 1 1 1 2 2 2 0 DivIVA protein P4Ha_N PF08336.11 CDJ96545.1 - 2.4 8.2 6.7 0.39 10.7 0.7 2.5 3 1 1 4 4 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF4315 PF14193.6 CDJ96545.1 - 3.7 7.6 10.0 0.11 12.5 0.8 2.8 4 0 0 4 4 2 0 Domain of unknown function (DUF4315) Seryl_tRNA_N PF02403.22 CDJ96545.1 - 5.7 7.2 12.6 6.1 7.1 0.5 3.3 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Peptidase_M1 PF01433.20 CDJ96546.1 - 1e-54 185.4 0.3 1.2e-54 185.2 0.3 1.0 1 0 0 1 1 1 1 Peptidase family M1 domain Aminopep PF10023.9 CDJ96546.1 - 0.0037 16.7 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Putative aminopeptidase Peptidase_MA_2 PF13485.6 CDJ96546.1 - 0.016 14.9 0.3 0.036 13.7 0.3 1.5 1 1 0 1 1 1 0 Peptidase MA superfamily Peptidase_M61 PF05299.12 CDJ96546.1 - 2 8.8 4.5 49 4.4 2.6 2.9 2 1 0 2 2 2 0 M61 glycyl aminopeptidase ERAP1_C PF11838.8 CDJ96547.1 - 1.2e-54 186.0 0.0 1.7e-54 185.5 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 CDJ96548.1 - 3.1e-76 255.8 0.2 5.3e-76 255.0 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 CDJ96548.1 - 1.6e-49 169.2 0.0 3.2e-49 168.2 0.0 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CDJ96548.1 - 3.5e-41 141.4 0.0 9.8e-41 140.0 0.0 1.8 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 CDJ96549.1 - 1.5e-78 263.3 0.5 3.9e-78 262.0 0.5 1.8 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CDJ96549.1 - 1.9e-47 161.9 0.2 6.5e-46 156.9 0.0 2.2 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 CDJ96549.1 - 2.3e-21 76.6 0.0 4.6e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Aminopep PF10023.9 CDJ96549.1 - 0.00037 20.0 0.0 0.00067 19.1 0.0 1.3 1 0 0 1 1 1 1 Putative aminopeptidase DUF2773 PF10971.8 CDJ96549.1 - 0.063 13.4 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) Asp PF00026.23 CDJ96550.1 - 1e-45 156.6 0.0 1.2e-45 156.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ96550.1 - 2.6e-08 34.3 0.0 0.0007 19.9 0.0 2.3 2 0 0 2 2 2 2 Xylanase inhibitor N-terminal Asp PF00026.23 CDJ96551.1 - 6.8e-49 167.0 0.0 8.7e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ96551.1 - 1.7e-08 34.9 2.7 7.7e-08 32.8 2.7 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 CDJ96552.1 - 5.8e-53 180.4 0.0 1.1e-52 179.5 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ96552.1 - 6e-13 49.4 0.3 2.5e-12 47.4 0.1 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Amidinotransf PF02274.17 CDJ96555.1 - 1.7e-18 66.8 0.0 3.4e-17 62.5 0.0 2.0 1 1 0 1 1 1 1 Amidinotransferase Amidinotransf PF02274.17 CDJ96556.1 - 1.5e-26 93.3 0.0 4.6e-25 88.4 0.0 2.0 1 1 0 1 1 1 1 Amidinotransferase TrwB_AAD_bind PF10412.9 CDJ96556.1 - 0.18 10.7 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Lustrin_cystein PF14625.6 CDJ96557.1 - 2.6e-05 24.5 20.4 0.0074 16.6 5.6 2.5 2 1 0 2 2 2 2 Lustrin, cysteine-rich repeated domain Nodulin_late PF07127.11 CDJ96557.1 - 1.3 9.4 7.8 0.32 11.4 1.1 2.6 2 1 1 3 3 3 0 Late nodulin protein AAA PF00004.29 CDJ96558.1 - 2.5e-11 44.1 0.5 9.1e-11 42.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CDJ96558.1 - 3.9e-05 23.7 0.0 0.00029 20.8 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 CDJ96558.1 - 3.9e-05 23.7 0.0 0.001 19.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 CDJ96558.1 - 5.5e-05 23.4 0.1 0.00024 21.4 0.1 2.1 1 0 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 CDJ96558.1 - 6.7e-05 23.3 1.6 0.0023 18.3 1.6 3.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDJ96558.1 - 6.9e-05 23.1 1.5 0.0019 18.5 0.2 3.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CDJ96558.1 - 9.4e-05 22.2 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RFC1 PF08519.12 CDJ96558.1 - 0.00012 22.3 2.5 0.00026 21.2 0.3 2.5 3 0 0 3 3 2 1 Replication factor RFC1 C terminal domain AAA_33 PF13671.6 CDJ96558.1 - 0.00022 21.4 0.0 0.00022 21.4 0.0 2.6 3 0 0 3 3 2 1 AAA domain TIP49_C PF17856.1 CDJ96558.1 - 0.00077 19.6 0.2 0.0022 18.1 0.2 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain IstB_IS21 PF01695.17 CDJ96558.1 - 0.0015 18.3 0.0 0.0049 16.6 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 CDJ96558.1 - 0.0027 17.5 0.0 0.0078 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CDJ96558.1 - 0.0075 16.2 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA_6 PF12774.7 CDJ96558.1 - 0.015 14.3 0.2 0.44 9.5 0.0 2.3 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 CDJ96558.1 - 0.027 14.0 0.0 0.31 10.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 CDJ96558.1 - 0.036 14.1 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 CDJ96558.1 - 0.042 13.1 0.0 0.14 11.4 0.0 1.9 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 CDJ96558.1 - 0.054 14.0 0.0 0.86 10.1 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.6 CDJ96558.1 - 0.063 13.8 0.0 0.3 11.7 0.0 2.2 1 0 0 1 1 1 0 AAA domain Osmo_CC PF08946.10 CDJ96558.1 - 0.28 11.4 2.0 33 4.8 2.8 2.7 2 0 0 2 2 2 0 Osmosensory transporter coiled coil AAA_25 PF13481.6 CDJ96558.1 - 1.1 8.8 4.5 1.3 8.6 0.1 3.1 3 1 1 4 4 4 0 AAA domain NTF2 PF02136.20 CDJ96559.1 - 3.9e-18 66.2 2.4 6e-18 65.5 2.4 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 CDJ96559.1 - 2.7e-05 23.9 0.0 0.00018 21.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_GG_bind PF10258.9 CDJ96559.1 - 0.17 12.0 0.1 0.64 10.1 0.0 1.9 2 0 0 2 2 2 0 PHAX RNA-binding domain SNF2_N PF00176.23 CDJ96560.1 - 2.8e-72 243.4 1.9 2.8e-72 243.4 1.9 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ96560.1 - 7.1e-21 74.6 0.0 1e-18 67.7 0.0 3.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 CDJ96560.1 - 2.9e-20 72.1 0.0 7.9e-20 70.7 0.0 1.7 1 0 0 1 1 1 1 Bromodomain BRK PF07533.16 CDJ96560.1 - 1.2e-17 63.3 0.1 2.4e-17 62.2 0.1 1.6 1 0 0 1 1 1 1 BRK domain HSA PF07529.13 CDJ96560.1 - 3.2e-16 59.4 17.2 3.2e-16 59.4 17.2 5.0 4 0 0 4 4 4 1 HSA ResIII PF04851.15 CDJ96560.1 - 6.3e-10 39.3 0.0 6.3e-10 39.3 0.0 3.4 5 0 0 5 5 5 1 Type III restriction enzyme, res subunit QLQ PF08880.11 CDJ96560.1 - 1.5e-09 37.4 3.4 1.7e-09 37.3 0.9 2.3 2 0 0 2 2 2 1 QLQ DEAD PF00270.29 CDJ96560.1 - 0.00014 21.7 0.0 0.00045 20.0 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase adh_short PF00106.25 CDJ96561.1 - 3.3e-47 160.5 0.6 3.9e-47 160.2 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ96561.1 - 7e-42 143.6 0.1 8.7e-42 143.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ96561.1 - 1.3e-10 41.5 4.0 8.4e-10 38.8 4.0 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CDJ96561.1 - 3.9e-05 23.2 0.2 8.8e-05 22.1 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CDJ96561.1 - 0.0019 17.7 0.1 0.0027 17.2 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CDJ96561.1 - 0.0034 16.4 0.2 0.011 14.8 0.2 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_zinc_N PF00107.26 CDJ96561.1 - 0.052 13.5 0.4 0.096 12.7 0.4 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase zf-C2H2 PF00096.26 CDJ96562.1 - 6.2e-23 79.9 67.3 0.0011 19.3 3.6 8.7 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ96562.1 - 1e-17 63.3 72.2 0.0027 18.4 1.1 9.0 9 0 0 9 9 9 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDJ96562.1 - 1.1e-11 44.6 22.0 7.9e-07 29.2 0.7 8.9 10 0 0 10 10 8 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 CDJ96562.1 - 0.0081 16.1 62.1 0.024 14.7 1.4 8.5 9 1 0 9 9 9 4 C2H2-type zinc finger zf-C2HC_2 PF13913.6 CDJ96562.1 - 0.024 14.5 1.2 0.024 14.5 1.2 5.9 6 0 0 6 6 6 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 CDJ96562.1 - 0.029 14.1 0.7 0.029 14.1 0.7 7.8 8 1 0 8 8 8 0 zinc-finger C2H2-type zf-met PF12874.7 CDJ96562.1 - 0.047 14.1 1.4 0.047 14.1 1.4 7.7 8 0 0 8 8 7 0 Zinc-finger of C2H2 type DUF2256 PF10013.9 CDJ96562.1 - 0.33 11.1 25.5 1.2 9.3 0.1 7.3 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_jaz PF12171.8 CDJ96562.1 - 1.1 9.6 49.3 1.2 9.6 0.1 9.3 10 0 0 10 10 10 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 CDJ96562.1 - 1.6 9.6 30.6 0.13 13.0 2.8 5.8 4 2 2 6 6 6 0 zinc-ribbon family NRIP1_repr_3 PF15689.5 CDJ96562.1 - 4.8 7.5 7.1 1 9.7 2.7 2.2 2 0 0 2 2 2 0 Nuclear receptor-interacting protein 1 repression 3 Zn-ribbon_8 PF09723.10 CDJ96562.1 - 7.8 6.7 37.2 0.2 11.8 0.5 6.8 4 1 3 7 7 7 0 Zinc ribbon domain XTBD PF11952.8 CDJ96563.1 - 0.061 13.1 0.1 0.086 12.6 0.1 1.3 1 0 0 1 1 1 0 XRN-Two Binding Domain, XTBD MtN3_slv PF03083.16 CDJ96564.1 - 8.3e-27 93.1 5.0 9.3e-27 92.9 5.0 1.0 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 CDJ96564.1 - 0.0015 18.3 0.3 0.0015 18.3 0.3 2.2 1 1 1 2 2 2 1 PQ loop repeat LAB_N PF07578.11 CDJ96564.1 - 0.014 15.4 0.3 0.023 14.8 0.2 1.5 1 1 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain TRIQK PF15168.6 CDJ96564.1 - 0.029 14.2 1.0 0.058 13.3 1.0 1.5 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family TK PF00265.18 CDJ96565.1 - 9.5e-54 181.9 0.1 1.2e-53 181.6 0.1 1.1 1 0 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.6 CDJ96565.1 - 0.052 13.6 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DDE_Tnp_1_6 PF13751.6 CDJ96565.1 - 0.058 13.6 0.3 0.12 12.6 0.3 1.5 1 0 0 1 1 1 0 Transposase DDE domain SWIM PF04434.17 CDJ96566.1 - 0.0013 18.3 7.5 0.0039 16.8 7.5 1.8 1 0 0 1 1 1 1 SWIM zinc finger BBS2_C PF14782.6 CDJ96567.1 - 1.1e-102 344.1 1.3 1.6e-101 340.2 0.9 2.0 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 CDJ96567.1 - 1.3e-33 115.3 0.3 1.1e-32 112.3 0.0 2.3 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Itfg2 PF15907.5 CDJ96567.1 - 0.021 13.9 0.2 0.74 8.8 0.0 2.8 2 1 1 3 3 3 0 Integrin-alpha FG-GAP repeat-containing protein 2 VCBS PF13517.6 CDJ96567.1 - 0.13 12.8 0.1 0.61 10.7 0.1 2.1 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Peptidase_A17 PF05380.13 CDJ96570.1 - 8.1e-43 146.2 0.0 1.5e-42 145.3 0.0 1.5 1 0 0 1 1 1 1 Pao retrotransposon peptidase DUF1758 PF05585.12 CDJ96570.1 - 2.2e-07 30.8 0.8 7.2e-07 29.1 0.8 1.9 1 1 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 CDJ96570.1 - 0.0004 21.0 0.2 0.0016 19.1 0.1 2.0 1 1 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.8 CDJ96570.1 - 0.0011 18.6 0.4 0.0026 17.4 0.4 1.6 1 0 0 1 1 1 1 Ty3 transposon peptidase RVP_2 PF08284.11 CDJ96570.1 - 0.0012 18.6 0.1 0.0039 17.0 0.1 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CDJ96570.1 - 0.0016 19.0 0.1 0.0049 17.4 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DNA_pol_viral_C PF00336.18 CDJ96570.1 - 0.029 13.8 0.0 0.071 12.5 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Comm PF15957.5 CDJ96571.1 - 0.05 13.9 0.2 0.1 13.0 0.2 1.6 1 1 0 1 1 1 0 Commissureless UPF0767 PF15990.5 CDJ96571.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.5 1 1 0 1 1 1 0 UPF0767 family Presenilin PF01080.17 CDJ96571.1 - 0.13 11.0 4.6 0.14 10.9 4.6 1.1 1 0 0 1 1 1 0 Presenilin OATP PF03137.20 CDJ96571.1 - 0.14 10.4 0.1 0.15 10.3 0.1 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SID-1_RNA_chan PF13965.6 CDJ96571.1 - 0.18 10.2 0.2 0.18 10.2 0.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.16 CDJ96571.1 - 0.32 11.0 2.6 0.34 10.9 2.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4834 PF16118.5 CDJ96571.1 - 0.82 10.7 10.3 0.82 10.7 2.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) Kinesin PF00225.23 CDJ96572.1 - 5e-51 173.6 0.0 1.7e-28 99.6 0.0 2.2 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CDJ96572.1 - 5e-15 55.7 1.2 3.2e-14 53.1 0.1 2.4 2 1 0 2 2 2 1 Microtubule binding GAS PF13851.6 CDJ96572.1 - 0.018 14.4 7.4 0.029 13.7 7.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Kinesin_assoc PF16183.5 CDJ96572.1 - 0.027 14.6 9.3 0.04 14.1 0.8 2.3 1 1 1 2 2 2 0 Kinesin-associated DUF5339 PF17274.2 CDJ96572.1 - 0.045 14.6 5.5 0.15 12.9 1.8 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5339) Syntaxin_2 PF14523.6 CDJ96572.1 - 0.061 13.7 2.4 0.13 12.7 1.8 1.8 1 1 1 2 2 2 0 Syntaxin-like protein FlxA PF14282.6 CDJ96572.1 - 0.081 12.9 7.9 0.074 13.0 2.3 2.4 1 1 1 2 2 2 0 FlxA-like protein Fib_alpha PF08702.10 CDJ96572.1 - 0.087 13.0 2.2 0.17 12.0 2.2 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Mod_r PF07200.13 CDJ96572.1 - 0.13 12.4 5.6 0.26 11.4 5.6 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Bap31_Bap29_C PF18035.1 CDJ96572.1 - 0.17 11.9 5.9 0.4 10.7 5.9 1.7 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain HIP1_clath_bdg PF16515.5 CDJ96572.1 - 0.22 12.2 7.7 0.47 11.1 7.7 1.5 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TolA_bind_tri PF16331.5 CDJ96572.1 - 1.3 9.2 9.0 1.8 8.7 1.9 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF87 PF01935.17 CDJ96572.1 - 1.5 8.8 4.3 17 5.4 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain UPF0242 PF06785.11 CDJ96572.1 - 3.1 7.9 9.6 6.2 6.9 9.6 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CLU PF13236.6 CDJ96573.1 - 1.3e-84 283.4 0.0 2.4e-84 282.6 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 CDJ96573.1 - 2.1e-46 158.2 0.0 7.2e-45 153.2 0.0 2.8 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.6 CDJ96573.1 - 8.2e-15 54.9 0.0 3.3e-14 53.0 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.6 CDJ96573.1 - 1.9e-11 44.1 11.3 3.3e-06 27.3 0.4 4.1 2 2 3 5 5 5 5 Tetratricopeptide repeat DUF727 PF05303.12 CDJ96573.1 - 1.4e-07 31.5 0.0 4.3e-07 29.9 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_10 PF13374.6 CDJ96573.1 - 0.00015 21.5 10.2 0.017 15.0 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ96573.1 - 0.0021 18.1 1.4 7.4 6.9 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat ubiquitin PF00240.23 CDJ96573.1 - 0.16 11.7 0.0 0.41 10.4 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family TPR_4 PF07721.14 CDJ96573.1 - 3 8.7 10.0 36 5.4 0.6 3.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ96573.1 - 3.8 8.2 8.8 2.4 8.9 1.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-Di19 PF05605.12 CDJ96574.1 - 7.5e-09 35.8 4.1 0.00062 20.0 1.3 2.3 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 CDJ96574.1 - 9.8e-05 22.9 3.2 0.11 13.4 0.1 2.6 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CDJ96574.1 - 0.0093 16.3 4.8 0.017 15.4 4.8 1.5 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 CDJ96574.1 - 0.012 16.2 3.6 0.27 11.9 1.0 2.5 2 1 1 3 3 3 0 FOXP coiled-coil domain RNF220 PF15926.5 CDJ96574.1 - 0.014 15.1 5.5 0.44 10.1 2.9 2.0 1 1 1 2 2 2 0 E3 ubiquitin-protein ligase RNF220 zf-C2H2_9 PF16293.5 CDJ96574.1 - 0.021 14.6 2.5 0.22 11.4 0.5 2.3 1 1 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Prok-RING_4 PF14447.6 CDJ96574.1 - 0.022 14.6 0.3 6 6.8 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF2225 PF09986.9 CDJ96574.1 - 0.041 13.6 0.6 6.8 6.4 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) OrsD PF12013.8 CDJ96574.1 - 0.073 13.5 1.6 0.73 10.3 0.1 2.0 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Rad50_zn_hook PF04423.14 CDJ96574.1 - 0.1 12.5 3.7 3.3 7.6 0.2 2.4 1 1 0 2 2 2 0 Rad50 zinc hook motif zf-WRNIP1_ubi PF18279.1 CDJ96574.1 - 0.11 13.1 0.1 28 5.7 0.0 2.5 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-C2H2_jaz PF12171.8 CDJ96574.1 - 0.12 12.6 2.8 15 6.0 1.3 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-C2H2_12 PF18112.1 CDJ96574.1 - 0.15 12.6 3.8 6.9 7.2 0.4 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Prok-RING_1 PF14446.6 CDJ96574.1 - 0.21 11.5 2.9 2.1 8.4 0.7 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 CDJ96574.1 - 0.44 10.9 3.6 1.6 9.1 1.2 2.2 2 0 0 2 2 2 0 Ring finger domain HNH PF01844.23 CDJ96574.1 - 0.94 9.7 7.3 6.3 7.1 0.1 2.4 2 0 0 2 2 2 0 HNH endonuclease zf-ISL3 PF14690.6 CDJ96574.1 - 2.8 8.7 5.4 1.4 9.7 0.2 2.9 3 2 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 E7 PF00527.18 CDJ96574.1 - 5.5 7.3 7.3 0.92 9.8 0.6 2.3 1 1 2 3 3 3 0 E7 protein, Early protein zf-H2C2_2 PF13465.6 CDJ96574.1 - 6.7 7.3 7.0 30 5.3 0.1 3.3 4 0 0 4 4 4 0 Zinc-finger double domain FF PF01846.19 CDJ96576.1 - 3.4e-31 107.2 23.0 2.5e-12 46.8 0.1 5.7 6 0 0 6 6 6 4 FF domain WW PF00397.26 CDJ96576.1 - 3.7e-19 68.5 18.7 2.3e-09 37.2 2.7 2.8 2 0 0 2 2 2 2 WW domain OST_P2 PF18235.1 CDJ96576.1 - 0.031 14.2 0.3 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 Oligosaccharyltransferase Peripheral 2 domain TRAPP PF04051.16 CDJ96577.1 - 1.2e-23 83.4 0.0 1.5e-23 83.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component MTS PF05175.14 CDJ96578.1 - 1.3e-18 67.1 0.0 1.9e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CDJ96578.1 - 8.3e-12 45.7 0.1 1.6e-11 44.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ96578.1 - 2e-11 43.9 0.0 2.7e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 CDJ96578.1 - 3.5e-10 39.9 0.0 5e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 CDJ96578.1 - 9.2e-09 35.1 0.3 1.2e-08 34.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 CDJ96578.1 - 1.4e-08 35.3 0.0 2.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CDJ96578.1 - 3.1e-08 33.5 0.0 3.7e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 CDJ96578.1 - 1e-07 32.6 0.0 2.7e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.16 CDJ96578.1 - 1.4e-06 27.7 0.0 1.7e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_15 PF09445.10 CDJ96578.1 - 2.1e-06 27.4 0.1 3.1e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 CDJ96578.1 - 1e-05 25.5 0.2 1.7e-05 24.8 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 CDJ96578.1 - 1.3e-05 24.7 0.0 1.7e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Ubie_methyltran PF01209.18 CDJ96578.1 - 1.3e-05 24.7 0.0 1.6e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family AviRa PF11599.8 CDJ96578.1 - 6e-05 22.6 0.6 0.0017 17.9 0.3 2.2 1 1 1 2 2 2 1 RRNA methyltransferase AviRa Methyltransf_9 PF08003.11 CDJ96578.1 - 0.00022 20.3 0.1 0.00031 19.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Met_10 PF02475.16 CDJ96578.1 - 0.00027 20.8 0.0 0.0004 20.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Spermine_synth PF01564.17 CDJ96578.1 - 0.00047 19.6 0.0 0.00089 18.7 0.1 1.4 1 1 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 CDJ96578.1 - 0.001 18.9 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CDJ96578.1 - 0.0017 18.4 0.0 0.0024 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 CDJ96578.1 - 0.0032 17.1 0.0 0.0048 16.5 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F CMAS PF02353.20 CDJ96578.1 - 0.006 15.9 0.0 0.0072 15.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TPMT PF05724.11 CDJ96578.1 - 0.0071 16.0 0.1 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_16 PF10294.9 CDJ96578.1 - 0.011 15.5 1.1 0.03 14.0 0.1 1.9 2 0 0 2 2 2 0 Lysine methyltransferase Methyltransf_4 PF02390.17 CDJ96578.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.19 CDJ96578.1 - 0.02 14.7 0.0 0.027 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 CDJ96578.1 - 0.026 14.1 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 rRNA_methylase PF06962.12 CDJ96578.1 - 0.097 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative rRNA methylase N6-adenineMlase PF10237.9 CDJ96578.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase DUF1759 PF03564.15 CDJ96580.1 - 5e-20 71.9 0.0 7e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Retrotran_gag_2 PF14223.6 CDJ96580.1 - 0.047 13.4 0.4 0.075 12.7 0.4 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type V-ATPase_H_C PF11698.8 CDJ96580.1 - 0.054 13.6 2.9 0.23 11.6 2.9 2.0 1 1 0 1 1 1 0 V-ATPase subunit H Laminin_II PF06009.12 CDJ96580.1 - 0.063 13.3 0.2 0.13 12.2 0.1 1.6 1 1 0 1 1 1 0 Laminin Domain II MutS_III PF05192.18 CDJ96580.1 - 0.11 12.8 1.2 0.15 12.3 1.2 1.4 1 1 0 1 1 1 0 MutS domain III WXG100 PF06013.12 CDJ96581.1 - 0.036 14.3 1.4 0.058 13.6 0.3 2.0 2 0 0 2 2 2 0 Proteins of 100 residues with WXG FH2 PF02181.23 CDJ96583.1 - 2.7e-94 316.4 4.0 2.7e-94 316.4 4.0 2.6 2 1 1 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.13 CDJ96583.1 - 3.5e-23 82.1 9.2 3.5e-23 82.1 9.2 2.7 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 CDJ96583.1 - 7.2e-20 71.4 9.7 2.5e-19 69.6 9.7 2.0 1 0 0 1 1 1 1 Diaphanous FH3 Domain DUF1366 PF07104.11 CDJ96583.1 - 3.2 7.5 6.8 3.2 7.5 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1366) DUF3584 PF12128.8 CDJ96583.1 - 5.6 4.4 22.4 0.038 11.5 13.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Dak1 PF02733.17 CDJ96584.1 - 1.2e-56 191.9 3.3 1.5e-56 191.6 3.3 1.0 1 0 0 1 1 1 1 Dak1 domain Dak1 PF02733.17 CDJ96585.1 - 1.1e-25 90.2 0.0 1.3e-25 90.0 0.0 1.0 1 0 0 1 1 1 1 Dak1 domain ADH_zinc_N PF00107.26 CDJ96586.1 - 8.1e-25 87.3 0.1 1.3e-24 86.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CDJ96586.1 - 1.4e-09 37.8 0.7 2.4e-09 37.0 0.7 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 CDJ96586.1 - 0.00017 20.9 0.4 0.00027 20.3 0.4 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ShK PF01549.24 CDJ96588.1 - 0.00021 21.8 13.5 0.00038 20.9 13.5 1.4 1 0 0 1 1 1 1 ShK domain-like DUF5380 PF17351.2 CDJ96589.1 - 3.9e-43 145.2 0.0 4.4e-43 145.0 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5380) Cas9_REC PF16592.5 CDJ96589.1 - 0.052 12.3 0.1 0.055 12.2 0.1 1.0 1 0 0 1 1 1 0 REC lobe of CRISPR-associated endonuclease Cas9 mRNA_decap_C PF16741.5 CDJ96590.1 - 0.093 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 mRNA-decapping enzyme C-terminus Innexin PF00876.18 CDJ96591.1 - 5.3e-22 78.6 1.7 6.1e-22 78.4 1.7 1.0 1 0 0 1 1 1 1 Innexin Innexin PF00876.18 CDJ96592.1 - 3.9e-24 85.6 0.5 4.4e-24 85.4 0.5 1.0 1 0 0 1 1 1 1 Innexin ILVD_EDD PF00920.21 CDJ96593.1 - 0.17 10.5 0.0 0.19 10.3 0.0 1.0 1 0 0 1 1 1 0 Dehydratase family I-set PF07679.16 CDJ96594.1 - 6.5e-30 103.1 0.0 8.8e-16 57.8 0.0 2.9 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ96594.1 - 2e-16 60.4 0.0 1.2e-08 35.5 0.0 3.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 CDJ96594.1 - 8.3e-06 26.0 0.0 0.0019 18.5 0.0 2.9 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 CDJ96594.1 - 0.0008 19.5 0.1 2 8.7 0.0 3.8 3 0 0 3 3 3 1 Immunoglobulin domain C2-set_2 PF08205.12 CDJ96594.1 - 0.01 15.9 2.7 2.7 8.1 0.0 4.4 4 0 0 4 4 4 0 CD80-like C2-set immunoglobulin domain BACON PF13004.7 CDJ96594.1 - 0.12 12.4 7.0 0.63 10.1 0.4 4.2 4 0 0 4 4 4 0 Putative binding domain, N-terminal Sld7_C PF18596.1 CDJ96594.1 - 2.9 8.1 8.0 6 7.1 0.0 3.5 4 0 0 4 4 4 0 Sld7 C-terminal domain RVT_1 PF00078.27 CDJ96595.1 - 4.4e-24 85.2 0.0 7.9e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNAPolymera_Pol PF11590.8 CDJ96595.1 - 0.0019 18.0 0.1 0.0033 17.3 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase catalytic subunit Pol fn3 PF00041.21 CDJ96597.1 - 1.2e-194 631.3 2.6 1.8e-12 47.4 0.0 16.3 15 0 0 15 15 15 15 Fibronectin type III domain I-set PF07679.16 CDJ96597.1 - 1.8e-164 534.3 54.6 9e-16 57.7 0.0 21.7 20 1 0 20 20 20 17 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ96597.1 - 9.3e-101 330.6 36.2 4.9e-12 46.3 0.1 19.3 18 0 0 18 18 18 14 Immunoglobulin domain ig PF00047.25 CDJ96597.1 - 1.7e-39 133.8 39.0 1.9e-07 31.2 0.0 13.2 13 1 0 13 13 13 8 Immunoglobulin domain Ig_2 PF13895.6 CDJ96597.1 - 3.3e-37 126.7 25.0 4.9e-10 39.6 0.1 14.9 19 0 0 19 19 19 6 Immunoglobulin domain V-set PF07686.17 CDJ96597.1 - 8e-27 93.6 34.5 0.017 15.3 0.0 18.5 18 4 0 18 18 18 8 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 CDJ96597.1 - 5.1e-10 39.8 6.6 12 6.6 0.0 12.1 11 2 0 11 11 11 1 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 CDJ96597.1 - 6.9e-10 39.2 0.7 0.46 10.8 0.0 9.8 9 1 1 10 10 10 1 Interferon-alpha/beta receptor, fibronectin type III CE2_N PF17996.1 CDJ96597.1 - 2e-09 37.4 1.1 0.2 11.7 0.0 4.8 4 0 0 4 4 4 3 Carbohydrate esterase 2 N-terminal Izumo-Ig PF16706.5 CDJ96597.1 - 2.3e-09 37.2 9.0 0.28 11.3 0.0 11.0 15 0 0 15 15 15 2 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 CDJ96597.1 - 2.6e-09 37.2 28.0 3.5 7.9 0.0 13.4 15 4 3 18 18 17 5 Natural killer cell receptor 2B4 DUF2369 PF10179.9 CDJ96597.1 - 1.1e-05 25.7 1.1 18 5.8 0.0 7.3 7 0 0 7 7 6 0 Uncharacterised conserved protein (DUF2369) C2-set_2 PF08205.12 CDJ96597.1 - 7.9e-05 22.6 1.4 0.39 10.8 0.0 6.3 6 0 0 6 6 6 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 CDJ96597.1 - 0.035 13.7 0.0 9.2 5.9 0.0 3.9 3 0 0 3 3 3 0 Immunoglobulin domain MMR_HSR1_Xtn PF16897.5 CDJ96597.1 - 1.2 9.2 4.2 50 4.0 0.2 4.1 4 0 0 4 4 4 0 C-terminal region of MMR_HSR1 domain Ion_trans PF00520.31 CDJ96598.1 - 2.6e-38 131.6 7.8 4.6e-38 130.8 7.8 1.4 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 CDJ96598.1 - 7.2e-22 77.5 0.0 1.7e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 CDJ96598.1 - 9.9e-14 51.1 8.7 2.5e-13 49.8 8.7 1.7 1 0 0 1 1 1 1 Ion channel BTB_3 PF16017.5 CDJ96598.1 - 0.00083 19.4 0.0 0.0026 17.8 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain DUF423 PF04241.15 CDJ96598.1 - 0.051 13.8 0.1 0.17 12.1 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF423) PKD_channel PF08016.12 CDJ96598.1 - 1.1 7.9 9.4 0.059 12.0 3.6 1.7 2 0 0 2 2 2 0 Polycystin cation channel I-set PF07679.16 CDJ96599.1 - 3.1e-135 440.6 0.0 5.6e-22 77.6 0.0 8.6 8 1 0 8 8 8 8 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ96599.1 - 2.5e-92 303.5 3.5 4.2e-14 52.9 0.0 8.4 8 0 0 8 8 8 8 Immunoglobulin domain Ig_2 PF13895.6 CDJ96599.1 - 1.3e-52 176.1 8.0 3e-09 37.1 0.0 8.2 8 0 0 8 8 8 7 Immunoglobulin domain ig PF00047.25 CDJ96599.1 - 3.3e-52 174.6 5.5 4.1e-09 36.5 0.0 8.2 8 0 0 8 8 8 6 Immunoglobulin domain C2-set_2 PF08205.12 CDJ96599.1 - 5.7e-22 77.6 0.7 0.0075 16.3 0.0 7.8 8 0 0 8 8 8 5 CD80-like C2-set immunoglobulin domain V-set PF07686.17 CDJ96599.1 - 1.4e-21 76.7 15.5 0.00084 19.5 0.0 9.7 8 4 1 9 9 9 5 Immunoglobulin V-set domain Ig_4 PF16680.5 CDJ96599.1 - 6.3e-10 39.2 2.7 0.014 15.7 0.0 5.6 5 1 0 5 5 5 3 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.8 CDJ96599.1 - 7.8e-09 35.7 0.0 1.4 9.1 0.0 6.3 7 0 0 7 7 7 1 Natural killer cell receptor 2B4 C1-set PF07654.15 CDJ96599.1 - 3.9e-08 33.6 3.6 0.53 10.7 0.0 6.7 7 0 0 7 7 7 2 Immunoglobulin C1-set domain Ig_6 PF18452.1 CDJ96599.1 - 2e-07 30.5 6.2 1.3 8.6 0.0 5.4 5 0 0 5 5 5 3 Immunoglobulin domain Izumo-Ig PF16706.5 CDJ96599.1 - 6.6e-05 22.9 4.1 9.7 6.3 0.0 6.0 7 0 0 7 7 7 1 Izumo-like Immunoglobulin domain fn3 PF00041.21 CDJ96599.1 - 0.00048 20.4 0.0 0.0014 18.9 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain Adeno_E3_CR1 PF02440.15 CDJ96599.1 - 0.0017 18.1 6.2 1.1 9.1 0.0 4.7 6 0 0 6 6 6 2 Adenovirus E3 region protein CR1 V-set_CD47 PF08204.11 CDJ96599.1 - 0.052 13.5 7.2 2.4 8.1 0.0 5.3 7 0 0 7 7 6 0 CD47 immunoglobulin-like domain DUF608 PF04685.13 CDJ96600.1 - 8.7e-148 492.3 8.0 1.5e-147 491.5 8.0 1.4 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Glyco_hydr_116N PF12215.8 CDJ96600.1 - 8.9e-83 278.3 0.1 1.2e-82 277.8 0.1 1.2 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term zf-C2H2 PF00096.26 CDJ96604.1 - 1.9e-11 43.7 33.7 6.6e-05 23.1 1.7 5.0 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDJ96604.1 - 2.1e-09 37.3 23.0 5.6e-08 32.9 0.7 4.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDJ96604.1 - 3e-06 27.6 35.8 0.0042 17.8 1.3 5.2 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CDJ96604.1 - 1.3e-05 24.8 15.8 0.00024 20.8 3.0 3.8 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 CDJ96604.1 - 0.0054 17.0 10.5 0.2 12.0 0.5 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDJ96604.1 - 0.0098 16.3 0.8 0.0098 16.3 0.8 4.4 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_7 PF15269.6 CDJ96604.1 - 0.019 15.0 11.4 0.053 13.6 1.6 2.6 1 1 1 2 2 2 0 Zinc-finger zf-C2H2_2 PF12756.7 CDJ96604.1 - 1.2 9.5 20.3 1.9 8.9 12.9 4.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) CTU2 PF10288.9 CDJ96604.1 - 6.7 7.0 10.8 21 5.4 7.1 3.5 2 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 OAD_gamma PF04277.13 CDJ96605.1 - 0.00089 19.8 0.6 0.0091 16.6 0.6 2.0 1 1 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain PROL5-SMR PF15621.6 CDJ96605.1 - 0.029 14.9 1.8 0.045 14.3 1.8 1.5 1 1 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family CAP PF00188.26 CDJ96606.1 - 0.013 16.4 0.0 0.077 13.8 0.0 1.9 1 1 0 1 1 1 0 Cysteine-rich secretory protein family Sex_peptide PF08138.11 CDJ96607.1 - 0.57 10.4 2.6 0.39 10.9 0.5 1.8 2 0 0 2 2 2 0 Sex peptide (SP) family RRM_1 PF00076.22 CDJ96608.1 - 5.6e-32 109.4 0.0 2.9e-18 65.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CDJ96608.1 - 5e-07 29.7 0.0 0.04 14.0 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif RRM_7 PF16367.5 CDJ96608.1 - 0.0021 18.1 0.1 0.0053 16.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif RRM_1 PF00076.22 CDJ96609.1 - 1.3e-32 111.4 0.0 3e-18 65.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CDJ96609.1 - 4.5e-08 33.1 0.0 0.011 15.8 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif RRM_7 PF16367.5 CDJ96609.1 - 0.0065 16.6 0.0 0.016 15.3 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif GRP PF07172.11 CDJ96609.1 - 6 7.6 15.3 10 6.9 15.3 1.3 1 0 0 1 1 1 0 Glycine rich protein family RRM_1 PF00076.22 CDJ96610.1 - 1.3e-32 111.4 0.0 6e-19 67.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CDJ96610.1 - 1.2e-08 34.9 0.1 0.0033 17.4 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif RRM_7 PF16367.5 CDJ96610.1 - 0.0042 17.2 0.0 0.011 15.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 CDJ96610.1 - 0.005 16.8 0.0 0.56 10.3 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 CDJ96610.1 - 0.11 12.2 0.2 23 4.7 0.2 2.7 2 1 0 2 2 2 0 Histone lysine methyltransferase SET associated PRP38_assoc PF12871.7 CDJ96610.1 - 0.21 12.2 23.7 7.2 7.3 23.4 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term RRM_occluded PF16842.5 CDJ96610.1 - 0.23 11.3 0.0 0.46 10.4 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif GRP PF07172.11 CDJ96610.1 - 8.1 7.2 20.5 19 6.0 16.0 2.2 2 0 0 2 2 2 0 Glycine rich protein family RRM_1 PF00076.22 CDJ96611.1 - 3.8e-30 103.5 0.0 2.7e-19 68.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CDJ96611.1 - 4.5e-08 33.1 0.1 0.0046 17.0 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif RRM_7 PF16367.5 CDJ96611.1 - 0.0056 16.8 0.0 0.019 15.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif SET_assoc PF11767.8 CDJ96611.1 - 0.02 14.6 1.9 1.7 8.4 0.0 2.8 2 1 1 3 3 3 0 Histone lysine methyltransferase SET associated RRM_occluded PF16842.5 CDJ96611.1 - 0.029 14.2 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CDJ96611.1 - 0.031 14.3 0.0 0.35 10.9 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CDJ96611.1 - 0.084 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4429 PF14472.6 CDJ96611.1 - 0.088 13.4 0.3 1.1 9.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4429) F-box-like PF12937.7 CDJ96612.1 - 4.1e-09 36.2 0.2 1.4e-08 34.5 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDJ96612.1 - 8.2e-07 28.7 1.5 3.4e-05 23.6 0.3 2.7 2 0 0 2 2 2 1 F-box domain pXO2-72 PF17443.2 CDJ96612.1 - 0.15 12.3 0.0 0.53 10.6 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein pXO2-72 Abhydrolase_6 PF12697.7 CDJ96614.1 - 9.5e-27 95.0 0.1 1.3e-26 94.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDJ96614.1 - 4.2e-16 59.4 0.0 5.8e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ96614.1 - 2.7e-08 33.4 0.0 4.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 CDJ96614.1 - 3.4e-06 27.0 0.0 3.1e-05 23.8 0.0 2.0 1 1 1 2 2 2 1 PGAP1-like protein LIDHydrolase PF10230.9 CDJ96614.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 CDJ96614.1 - 0.013 15.4 0.4 0.094 12.6 0.4 2.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 CDJ96614.1 - 0.032 14.3 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.25 CDJ96614.1 - 0.049 13.5 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.7 CDJ96614.1 - 0.06 12.2 0.1 0.14 11.1 0.1 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.20 CDJ96614.1 - 0.11 12.1 0.0 0.68 9.5 0.0 2.0 2 0 0 2 2 2 0 Putative esterase Chlorophyllase PF07224.11 CDJ96614.1 - 0.19 10.7 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase BNIP3 PF06553.12 CDJ96615.1 - 0.18 11.5 2.3 0.18 11.4 2.3 1.3 1 1 0 1 1 1 0 BNIP3 SET PF00856.28 CDJ96616.1 - 4.9e-09 36.8 0.2 1.1e-08 35.7 0.2 1.7 1 1 0 1 1 1 1 SET domain HLH PF00010.26 CDJ96617.1 - 3.6e-17 62.1 2.5 8.3e-17 60.9 2.5 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Cnn_1N PF07989.11 CDJ96617.1 - 0.053 13.7 1.1 0.14 12.3 0.1 2.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 CCDC92 PF14916.6 CDJ96617.1 - 0.54 10.1 3.9 6.7 6.6 0.2 3.1 3 0 0 3 3 3 0 Coiled-coil domain of unknown function ANAPC4_WD40 PF12894.7 CDJ96618.1 - 5.1e-18 65.1 0.7 1.3e-17 63.9 0.7 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain ANAPC4 PF12896.7 CDJ96618.1 - 2.7e-05 23.8 0.4 2.7e-05 23.8 0.4 2.4 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 WD40 PF00400.32 CDJ96618.1 - 0.0098 16.7 0.0 0.16 12.9 0.0 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat DSPc PF00782.20 CDJ96619.1 - 6.1e-15 55.2 0.0 1.3e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Cnd1_N PF12922.7 CDJ96619.1 - 0.016 15.1 0.6 0.04 13.8 0.6 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Y_phosphatase PF00102.27 CDJ96619.1 - 0.075 12.6 1.0 0.087 12.4 0.0 1.6 2 0 0 2 2 2 0 Protein-tyrosine phosphatase RHH_5 PF07878.11 CDJ96619.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 Spt5_N PF11942.8 CDJ96619.1 - 4.2 8.4 16.4 1.4 10.0 6.4 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DHHC PF01529.20 CDJ96620.1 - 1.9e-35 121.9 13.0 1.9e-35 121.9 13.0 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase PalH PF08733.10 CDJ96620.1 - 0.1 11.6 1.3 0.17 10.9 1.3 1.2 1 0 0 1 1 1 0 PalH/RIM21 PseudoU_synth_1 PF01416.20 CDJ96621.1 - 4.5e-09 36.7 0.0 5.5e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 tRNA pseudouridine synthase A2M_recep PF07677.14 CDJ96622.1 - 1.2e-22 80.4 0.4 8.1e-18 64.9 0.0 2.1 1 1 1 2 2 2 2 A-macroglobulin receptor binding domain Glyco_trans_A_1 PF09318.10 CDJ96622.1 - 5.6e-05 22.9 0.2 0.00012 21.8 0.2 1.5 1 1 0 1 1 1 1 Glycosyl transferase 1 domain A zf-Dof PF02701.15 CDJ96622.1 - 0.24 11.6 1.4 2 8.6 0.1 2.4 1 1 1 2 2 2 0 Dof domain, zinc finger C_tripleX PF02363.19 CDJ96625.1 - 0.00012 22.1 184.5 0.036 14.3 11.9 12.5 12 0 0 12 12 12 11 Cysteine rich repeat 7TM_GPCR_Srw PF10324.9 CDJ96626.1 - 8.6e-41 140.2 20.8 1.1e-40 139.9 20.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Abhydrolase_9_N PF15420.6 CDJ96626.1 - 0.36 10.8 9.1 0.4 10.6 4.3 2.4 2 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF3976 PF13121.6 CDJ96626.1 - 3.6 7.8 8.8 9.6 6.4 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3976) UPF0182 PF03699.13 CDJ96626.1 - 6.6 4.7 13.0 7.6 4.5 13.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) PNISR PF15996.5 CDJ96627.1 - 1.8e-23 83.9 13.5 1.8e-23 83.9 13.5 3.3 1 1 2 3 3 3 1 Arginine/serine-rich protein PNISR Thioredoxin PF00085.20 CDJ96628.1 - 2.9e-13 49.7 0.0 3.9e-07 30.0 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 CDJ96628.1 - 4.9e-06 26.6 0.0 3.1e-05 24.0 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like domain TraF PF13728.6 CDJ96628.1 - 0.0014 18.5 0.0 0.015 15.2 0.0 2.3 2 0 0 2 2 2 1 F plasmid transfer operon protein RXLR PF16810.5 CDJ96628.1 - 0.015 15.7 0.0 0.09 13.2 0.0 2.1 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity ERp29_N PF07912.13 CDJ96628.1 - 0.07 13.3 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 ERp29, N-terminal domain Macoilin PF09726.9 CDJ96629.1 - 2.5e-76 257.7 36.8 6.3e-45 153.9 11.7 2.4 3 0 0 3 3 3 2 Macoilin family Neur_chan_memb PF02932.16 CDJ96630.1 - 1.8e-52 178.8 7.0 2.3e-52 178.4 7.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CDJ96630.1 - 8e-31 107.2 0.2 8e-31 107.2 0.2 1.6 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain TnsD PF15978.5 CDJ96630.1 - 0.00053 19.1 5.2 0.00077 18.6 5.2 1.1 1 0 0 1 1 1 1 Tn7-like transposition protein D DUF2417 PF10329.9 CDJ96630.1 - 3.8 6.9 9.8 4 6.8 5.5 2.2 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Ribosomal_L41 PF05162.13 CDJ96631.1 - 4.1e-06 26.7 22.5 8e-06 25.8 22.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L41 Profilin PF00235.19 CDJ96632.1 - 3.7e-26 91.9 0.0 4.3e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 Profilin IMD PF08397.11 CDJ96633.1 - 2.4e-22 79.4 1.0 2.2e-19 69.7 0.5 2.5 2 0 0 2 2 2 2 IRSp53/MIM homology domain MCPsignal PF00015.21 CDJ96633.1 - 0.083 12.7 0.9 0.49 10.2 0.0 2.5 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Cucumopine_C PF18631.1 CDJ96633.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Cucumopine synthase C-terminal helical bundle domain DUF1771 PF08590.10 CDJ96633.1 - 1.2 9.5 0.0 1.2 9.5 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1771) MAGUK_N_PEST PF10608.9 CDJ96633.1 - 9.1 6.8 8.3 15 6.0 4.3 2.7 2 0 0 2 2 2 0 Polyubiquitination (PEST) N-terminal domain of MAGUK MFS_1 PF07690.16 CDJ96634.1 - 1.3e-44 152.6 20.2 8.9e-41 140.0 16.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YrhC PF14143.6 CDJ96634.1 - 1.4 9.1 4.2 0.61 10.2 0.3 2.5 2 1 1 3 3 3 0 YrhC-like protein RVT_1 PF00078.27 CDJ96637.1 - 5.2e-41 140.6 0.1 1.1e-40 139.6 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3629 PF12302.8 CDJ96637.1 - 0.03 13.8 0.1 0.065 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) DivIC PF04977.15 CDJ96637.1 - 0.12 12.2 1.8 3.3 7.5 0.0 2.6 2 0 0 2 2 2 0 Septum formation initiator Pkinase PF00069.25 CDJ96639.1 - 2.6e-06 27.0 0.0 3.3e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ96639.1 - 0.003 16.9 0.0 0.0045 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SNF PF00209.18 CDJ96640.1 - 2.9e-88 296.8 27.8 6.8e-65 219.7 13.4 3.0 2 1 1 3 3 3 3 Sodium:neurotransmitter symporter family SL4P PF17618.2 CDJ96641.1 - 8.7e-12 44.9 0.0 1.6e-11 44.1 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized Strongylid L4 protein SNF PF00209.18 CDJ96645.1 - 3.5e-122 408.8 33.1 1.3e-99 334.3 20.1 2.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family Phage_holin_3_3 PF16083.5 CDJ96645.1 - 0.66 10.1 0.0 0.66 10.1 0.0 3.4 4 0 0 4 4 4 0 LydA holin phage, holin superfamily III Rootletin PF15035.6 CDJ96646.1 - 0.0076 16.3 20.6 0.0076 16.3 20.6 2.6 2 1 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion Na_trans_assoc PF06512.13 CDJ96646.1 - 0.01 16.2 7.2 0.01 16.2 7.2 1.7 2 0 0 2 2 2 1 Sodium ion transport-associated DUF3685 PF12452.8 CDJ96646.1 - 0.022 14.5 1.7 0.061 13.0 1.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) TACC_C PF05010.14 CDJ96646.1 - 0.089 12.6 24.8 2.3 8.0 0.0 3.8 3 1 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Golgin_A5 PF09787.9 CDJ96646.1 - 0.54 9.7 26.7 3.6 7.0 0.1 3.1 2 1 1 3 3 3 0 Golgin subfamily A member 5 KxDL PF10241.9 CDJ96646.1 - 2.4 8.5 9.8 1.3 9.4 3.1 3.3 2 1 0 2 2 2 0 Uncharacterized conserved protein DUF2390 PF09523.10 CDJ96647.1 - 0.049 13.9 0.1 0.076 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) SL4P PF17618.2 CDJ96649.1 - 1.7e-52 175.4 1.9 5.1e-22 77.7 0.0 3.3 2 1 1 3 3 3 3 Uncharacterized Strongylid L4 protein Leuk-A4-hydro_C PF09127.11 CDJ96650.1 - 2.3e-37 127.5 0.0 3.2e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal MATalpha_HMGbox PF04769.12 CDJ96650.1 - 0.011 15.1 0.5 0.017 14.5 0.2 1.4 2 0 0 2 2 2 0 Mating-type protein MAT alpha 1 HMG-box OSCP PF00213.18 CDJ96650.1 - 0.18 11.9 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit XkdW PF09636.10 CDJ96651.1 - 0.12 12.5 0.2 0.26 11.4 0.2 1.5 1 0 0 1 1 1 0 XkdW protein DMAP1 PF05499.12 CDJ96654.1 - 1.6e-51 174.5 1.1 1.6e-51 174.5 1.1 1.8 2 0 0 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) SANT_DAMP1_like PF16282.5 CDJ96654.1 - 8.3e-30 102.8 2.9 1.8e-29 101.7 2.9 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DUF4666 PF15697.5 CDJ96654.1 - 0.73 10.5 3.1 0.44 11.3 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) Ribosomal_S10 PF00338.22 CDJ96655.1 - 3.1e-28 97.9 0.1 3.7e-28 97.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e WWE PF02825.20 CDJ96656.1 - 7.4e-12 45.7 0.9 1.2e-11 45.0 0.9 1.3 1 0 0 1 1 1 1 WWE domain zf-RING_2 PF13639.6 CDJ96656.1 - 2.3e-07 31.1 8.0 4.6e-07 30.1 8.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CDJ96656.1 - 7.8e-07 28.9 8.3 1.6e-06 27.9 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ96656.1 - 1.1e-06 28.4 5.0 2.2e-06 27.4 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ96656.1 - 3.2e-06 26.9 10.0 5.9e-06 26.0 10.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ96656.1 - 1.6e-05 24.9 8.8 3.3e-05 23.9 8.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CDJ96656.1 - 7.4e-05 22.7 6.0 9.7e-05 22.3 4.3 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDJ96656.1 - 0.0014 18.5 8.9 0.0041 17.1 9.0 1.8 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDJ96656.1 - 0.0051 16.6 9.2 0.11 12.4 8.0 2.7 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CDJ96656.1 - 0.0062 16.8 7.1 0.0062 16.8 7.1 1.9 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-Di19 PF05605.12 CDJ96656.1 - 0.04 14.2 1.8 3 8.2 0.2 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.6 CDJ96656.1 - 0.051 13.4 8.7 0.97 9.3 9.0 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 CDJ96656.1 - 0.083 12.9 4.4 1.3 9.1 4.5 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 CDJ96656.1 - 0.31 10.9 4.3 0.63 9.9 4.3 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 CDJ96656.1 - 0.78 9.7 3.9 1.8 8.5 3.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 CDJ96656.1 - 0.93 9.7 4.5 2.3 8.4 4.5 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_5 PF17121.5 CDJ96656.1 - 3.2 7.7 8.3 12 5.9 8.3 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 CDJ96656.1 - 3.3 7.5 8.1 10 5.9 8.1 1.8 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zinc-ribbons_6 PF07191.12 CDJ96656.1 - 6.4 6.8 7.8 0.73 9.9 3.2 1.8 2 0 0 2 2 2 0 zinc-ribbons CAF1-p150_C2 PF15539.6 CDJ96657.1 - 0.013 15.0 0.1 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term SOAR PF16533.5 CDJ96657.1 - 0.35 10.9 2.4 1.4 8.9 0.8 2.2 2 0 0 2 2 2 0 STIM1 Orai1-activating region Homeodomain PF00046.29 CDJ96658.1 - 2.2e-23 81.9 1.1 4.8e-23 80.8 1.1 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ96658.1 - 0.052 13.5 0.1 0.15 12.0 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain GlgS PF08971.11 CDJ96658.1 - 0.2 11.7 2.3 0.92 9.6 2.0 2.1 1 1 1 2 2 2 0 Glycogen synthesis protein DUF2464 PF10240.9 CDJ96659.1 - 3.5e-59 200.5 0.0 4.4e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 Multivesicular body subunit 12 ApeC PF16977.5 CDJ96659.1 - 0.0032 17.4 0.0 0.018 15.0 0.0 1.9 2 0 0 2 2 2 1 C-terminal domain of apextrin Collagen PF01391.18 CDJ96660.1 - 6.2e-23 80.3 96.1 2.8e-10 39.8 29.1 4.1 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ96660.1 - 2.7e-07 30.6 0.3 3.7e-07 30.1 0.3 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain FERM_M PF00373.18 CDJ96661.1 - 1.4e-20 73.8 1.6 2.6e-20 73.0 0.7 2.0 2 0 0 2 2 2 1 FERM central domain FERM_C PF09380.10 CDJ96661.1 - 1.2e-11 44.9 0.0 2.3e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 CDJ96661.1 - 2.7e-09 36.8 0.0 1.3e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 FERM N-terminal domain LIM PF00412.22 CDJ96662.1 - 2.5e-19 69.2 18.8 3.8e-11 43.0 6.9 2.1 2 0 0 2 2 2 2 LIM domain zf-RRN7 PF11781.8 CDJ96662.1 - 0.0016 18.1 4.6 0.0016 18.1 4.6 2.9 4 0 0 4 4 4 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Dynactin_p62 PF05502.13 CDJ96662.1 - 0.088 11.6 2.8 0.11 11.3 2.8 1.2 1 0 0 1 1 1 0 Dynactin p62 family zf-BED PF02892.15 CDJ96662.1 - 0.43 10.6 10.3 1.2 9.2 0.2 3.4 3 1 0 3 3 3 0 BED zinc finger Terminase_GpA PF05876.12 CDJ96662.1 - 5.6 5.4 6.7 5.7 5.4 6.7 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) DUF1631 PF07793.11 CDJ96663.1 - 0.12 10.7 0.0 0.14 10.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) SDF PF00375.18 CDJ96664.1 - 1.4e-118 396.3 27.7 1.6e-118 396.1 27.7 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF2318 PF10080.9 CDJ96665.1 - 0.14 12.3 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Arrestin_C PF02752.22 CDJ96666.1 - 7.3e-19 68.5 0.1 2.8e-13 50.5 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CDJ96666.1 - 2.3e-15 56.9 0.1 2.6e-12 47.0 0.0 2.8 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 CDJ96666.1 - 4.1e-05 22.9 0.3 0.16 11.1 0.0 2.2 2 0 0 2 2 2 2 Rgp1 Vps26 PF03643.15 CDJ96666.1 - 0.04 12.9 0.0 1 8.3 0.0 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 26 ECH_1 PF00378.20 CDJ96667.1 - 1.2e-32 113.2 0.8 1.9e-32 112.6 0.3 1.5 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ACBP PF00887.19 CDJ96667.1 - 1.6e-25 89.1 0.3 1.6e-25 89.1 0.3 2.0 3 0 0 3 3 3 1 Acyl CoA binding protein ECH_2 PF16113.5 CDJ96667.1 - 2.5e-24 86.4 0.1 3.4e-24 86.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Dmd PF17587.2 CDJ96667.1 - 0.054 13.8 0.1 1.8 9.0 0.0 2.6 2 0 0 2 2 2 0 Discriminator of mRNA degradation Adaptin_N PF01602.20 CDJ96669.1 - 4.1e-106 355.6 1.9 5.9e-106 355.1 1.9 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 CDJ96669.1 - 3.7e-54 182.4 0.5 8.3e-54 181.3 0.5 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 CDJ96669.1 - 5.1e-53 178.5 0.0 1.4e-52 177.1 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.6 CDJ96669.1 - 4.4e-08 33.4 0.9 0.11 12.9 0.0 5.5 2 2 3 6 6 6 2 HEAT repeats Cnd1 PF12717.7 CDJ96669.1 - 1.7e-07 31.5 3.5 0.0006 19.9 0.0 3.8 1 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CDJ96669.1 - 2.8e-07 30.2 0.1 0.82 10.1 0.0 5.7 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 CDJ96669.1 - 4.2e-06 27.1 1.3 2.6 8.7 0.0 5.1 5 0 0 5 5 5 2 HEAT-like repeat Arm PF00514.23 CDJ96669.1 - 0.002 18.1 0.1 5.9 7.1 0.0 3.8 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat eIF3_N PF09440.10 CDJ96669.1 - 0.024 15.1 0.2 0.081 13.4 0.2 1.9 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain GUN4_N PF16416.5 CDJ96669.1 - 0.026 14.5 0.3 2.3 8.3 0.1 3.7 4 0 0 4 4 4 0 ARM-like repeat domain, GUN4-N terminal zf-RanBP PF00641.18 CDJ96670.1 - 2.6e-08 33.0 19.1 1.5e-06 27.4 8.4 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 CDJ96670.1 - 0.0064 16.5 11.7 0.025 14.6 10.6 2.3 1 1 1 2 2 2 2 Double zinc ribbon RecR PF02132.15 CDJ96670.1 - 2.4 7.8 7.6 0.14 11.7 1.2 2.1 2 0 0 2 2 2 0 RecR protein A2L_zn_ribbon PF08792.10 CDJ96670.1 - 2.8 7.8 8.1 7 6.5 0.3 3.3 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-RRN7 PF11781.8 CDJ96670.1 - 2.9 7.7 12.0 4.1 7.2 0.9 3.4 2 1 1 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 V-ATPase_G PF03179.15 CDJ96671.1 - 0.78 10.3 10.8 1.2 9.7 2.5 2.1 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit Nop14 PF04147.12 CDJ96671.1 - 4.3 5.4 15.4 4.8 5.3 15.4 1.0 1 0 0 1 1 1 0 Nop14-like family Yip1 PF04893.17 CDJ96673.1 - 2e-08 34.1 18.8 4.5e-08 33.0 16.2 2.0 1 1 1 2 2 2 2 Yip1 domain Paf67 PF10255.9 CDJ96674.1 - 0.034 13.2 0.2 0.04 12.9 0.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 Adaptin_N PF01602.20 CDJ96675.1 - 4.5e-65 220.2 0.1 5.6e-65 219.9 0.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 CDJ96675.1 - 4.4e-07 30.2 0.0 0.045 14.1 0.0 3.2 2 1 0 3 3 3 2 HEAT repeats HEAT PF02985.22 CDJ96675.1 - 1.1e-06 28.4 0.1 0.21 11.9 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat Cnd1 PF12717.7 CDJ96675.1 - 3.2e-06 27.3 0.2 6.4e-05 23.1 0.1 2.7 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CDJ96675.1 - 3.1e-05 24.4 0.0 0.62 10.6 0.0 3.1 3 0 0 3 3 3 2 HEAT-like repeat Arm PF00514.23 CDJ96675.1 - 0.0019 18.2 0.1 1.6 8.9 0.0 2.9 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat GUN4_N PF16416.5 CDJ96675.1 - 0.016 15.2 0.1 0.5 10.4 0.0 2.7 3 0 0 3 3 3 0 ARM-like repeat domain, GUN4-N terminal zf-CDGSH PF09360.10 CDJ96676.1 - 1.9e-21 76.0 1.9 1.2e-09 38.2 0.2 2.3 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type GDNF PF02351.16 CDJ96676.1 - 0.0068 17.3 0.4 0.63 11.0 0.0 2.1 2 0 0 2 2 2 2 GDNF/GAS1 domain MIP PF00230.20 CDJ96677.1 - 1.1 8.9 6.6 0.39 10.4 3.3 2.2 1 1 1 2 2 2 0 Major intrinsic protein Pkinase PF00069.25 CDJ96678.1 - 7.6e-06 25.5 0.0 9.8e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain NAP PF00956.18 CDJ96679.1 - 0.0061 15.8 0.8 0.0092 15.2 0.8 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) CREPT PF16566.5 CDJ96679.1 - 0.2 11.9 11.9 0.54 10.4 11.9 1.7 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour AAA_23 PF13476.6 CDJ96679.1 - 0.8 10.2 11.2 0.09 13.3 6.4 1.9 2 0 0 2 2 2 0 AAA domain Macoilin PF09726.9 CDJ96679.1 - 4.7 5.7 13.4 0.18 10.3 6.6 1.8 2 0 0 2 2 2 0 Macoilin family AMP-binding PF00501.28 CDJ96682.1 - 1e-101 340.6 0.0 1.3e-101 340.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Collagen PF01391.18 CDJ96682.1 - 1.4e-18 66.3 103.9 7.4e-07 28.8 38.7 4.5 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ96682.1 - 1.2e-11 44.5 1.2 2.2e-11 43.6 1.2 1.5 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain AMP-binding_C PF13193.6 CDJ96682.1 - 0.00022 22.1 0.3 0.00089 20.2 0.0 2.1 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain DZR PF12773.7 CDJ96683.1 - 0.0011 18.9 3.9 0.0056 16.7 1.4 2.7 2 0 0 2 2 2 1 Double zinc ribbon zinc-ribbons_6 PF07191.12 CDJ96683.1 - 0.024 14.6 3.7 0.21 11.6 0.7 3.0 3 0 0 3 3 3 0 zinc-ribbons Zn_ribbon_SprT PF17283.2 CDJ96683.1 - 0.69 9.9 6.1 0.15 12.0 1.8 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zinc_ribbon_2 PF13240.6 CDJ96683.1 - 1.4 8.7 8.2 0.24 11.1 0.3 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 CDJ96683.1 - 9.9 6.4 6.9 25 5.1 0.0 3.1 3 0 0 3 3 3 0 Zinc ribbon domain TSC22 PF01166.18 CDJ96684.1 - 0.0002 21.6 3.3 0.00064 20.0 3.3 1.9 1 0 0 1 1 1 1 TSC-22/dip/bun family FapA PF03961.13 CDJ96684.1 - 0.0032 16.2 3.2 0.0046 15.6 3.2 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A GAS PF13851.6 CDJ96684.1 - 0.0052 16.2 8.4 0.0052 16.2 8.4 2.1 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.9 CDJ96684.1 - 0.0067 16.7 3.4 0.0067 16.7 3.4 2.3 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3141 PF11339.8 CDJ96684.1 - 0.03 12.8 1.6 0.037 12.5 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) Pox_A_type_inc PF04508.12 CDJ96684.1 - 0.1 12.5 0.3 0.1 12.5 0.3 2.5 3 0 0 3 3 2 0 Viral A-type inclusion protein repeat YabA PF06156.13 CDJ96684.1 - 0.11 13.2 9.3 0.24 12.1 9.3 1.7 1 1 0 1 1 1 0 Initiation control protein YabA CCDC-167 PF15188.6 CDJ96684.1 - 0.14 12.5 10.6 0.83 10.0 6.0 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Occludin_ELL PF07303.13 CDJ96684.1 - 0.18 12.5 6.6 0.34 11.7 6.3 1.6 1 1 0 1 1 1 0 Occludin homology domain TelA PF05816.11 CDJ96684.1 - 0.18 10.8 12.8 0.62 9.1 6.8 2.1 1 1 1 2 2 2 0 Toxic anion resistance protein (TelA) ZapB PF06005.12 CDJ96684.1 - 0.22 12.0 13.4 0.29 11.6 12.2 1.9 1 1 0 1 1 1 0 Cell division protein ZapB UPF0242 PF06785.11 CDJ96684.1 - 0.26 11.4 10.0 0.43 10.6 10.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 CDJ96684.1 - 0.36 11.4 13.4 0.64 10.5 13.4 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region WD40_alt PF14077.6 CDJ96684.1 - 0.4 10.6 2.5 0.39 10.6 0.5 2.1 2 0 0 2 2 1 0 Alternative WD40 repeat motif AAA_23 PF13476.6 CDJ96684.1 - 0.43 11.1 6.3 0.6 10.6 6.3 1.2 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 CDJ96684.1 - 0.44 9.8 4.1 0.63 9.4 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Csm1_N PF18504.1 CDJ96684.1 - 0.46 10.8 13.9 0.14 12.5 4.4 2.9 2 1 1 3 3 3 0 Csm1 N-terminal domain V_ATPase_I PF01496.19 CDJ96684.1 - 0.54 8.1 7.8 0.7 7.7 7.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.11 CDJ96684.1 - 0.62 10.5 12.5 0.071 13.5 3.6 3.2 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF724 PF05266.14 CDJ96684.1 - 0.64 9.8 12.6 1.4 8.7 12.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Lzipper-MIP1 PF14389.6 CDJ96684.1 - 0.66 10.3 9.5 0.18 12.1 4.6 2.3 1 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 CENP-H PF05837.12 CDJ96684.1 - 0.72 10.3 14.0 0.55 10.7 11.9 1.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Ax_dynein_light PF10211.9 CDJ96684.1 - 0.89 9.5 13.3 1.5 8.8 13.3 1.4 1 1 0 1 1 1 0 Axonemal dynein light chain DivIC PF04977.15 CDJ96684.1 - 0.91 9.3 9.1 0.25 11.1 4.7 2.2 1 1 1 2 2 2 0 Septum formation initiator TFR_dimer PF04253.15 CDJ96684.1 - 1.2 9.2 5.1 0.91 9.6 3.2 1.8 1 1 1 2 2 2 0 Transferrin receptor-like dimerisation domain Mod_r PF07200.13 CDJ96684.1 - 1.4 9.0 16.2 2.5 8.2 1.3 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4140 PF13600.6 CDJ96684.1 - 1.5 9.3 8.3 1.5 9.3 2.2 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) CLZ PF16526.5 CDJ96684.1 - 2 8.9 11.4 0.4 11.1 4.3 2.4 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_2 PF07716.15 CDJ96684.1 - 2.2 8.4 9.2 0.98 9.5 5.1 2.4 2 0 0 2 2 2 0 Basic region leucine zipper Snapin_Pallidin PF14712.6 CDJ96684.1 - 4.4 7.8 12.8 1.2 9.6 6.8 2.2 1 1 1 2 2 2 0 Snapin/Pallidin Cep57_CLD_2 PF14197.6 CDJ96684.1 - 5.6 7.1 11.2 5.5 7.2 6.3 2.9 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 bZIP_1 PF00170.21 CDJ96684.1 - 8.6 6.5 11.7 0.67 10.1 4.7 2.6 1 1 2 3 3 3 0 bZIP transcription factor Filamin PF00630.19 CDJ96685.1 - 1.3e-73 244.4 2.1 3.6e-10 40.6 0.0 9.6 9 0 0 9 9 9 9 Filamin/ABP280 repeat CH PF00307.31 CDJ96685.1 - 4.7e-36 123.3 0.0 3.2e-12 46.6 0.0 3.5 3 0 0 3 3 3 3 Calponin homology (CH) domain DUF5060 PF16586.5 CDJ96685.1 - 3.9e-05 23.9 0.3 15 6.0 0.0 6.5 7 0 0 7 7 7 1 Domain of unknown function (DUF5060) Big_3_5 PF16640.5 CDJ96685.1 - 0.0079 16.3 5.3 10 6.4 0.1 5.7 7 0 0 7 7 7 2 Bacterial Ig-like domain (group 3) CAMSAP_CH PF11971.8 CDJ96685.1 - 0.16 11.8 0.0 18 5.2 0.0 2.6 2 0 0 2 2 2 0 CAMSAP CH domain Cupredoxin_1 PF13473.6 CDJ96685.1 - 0.6 10.3 7.6 6 7.0 0.7 4.6 6 0 0 6 6 6 0 Cupredoxin-like domain PHD PF00628.29 CDJ96686.1 - 3.6e-09 36.4 6.8 7.5e-09 35.4 6.8 1.6 1 0 0 1 1 1 1 PHD-finger WHIM1 PF15612.6 CDJ96686.1 - 4.8e-05 22.8 0.1 0.00012 21.5 0.1 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 PHD_2 PF13831.6 CDJ96686.1 - 0.19 11.3 1.2 0.49 10.0 1.2 1.7 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 CDJ96686.1 - 7.6 7.0 6.3 13 6.2 6.3 1.4 1 0 0 1 1 1 0 Ring finger domain RabGAP-TBC PF00566.18 CDJ96687.1 - 1.7e-55 188.0 1.4 2.6e-55 187.4 1.4 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Septin PF00735.18 CDJ96688.1 - 5.1e-97 324.5 0.1 8.4e-97 323.8 0.1 1.3 1 0 0 1 1 1 1 Septin AAA_22 PF13401.6 CDJ96688.1 - 0.0008 19.7 0.0 0.0035 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CDJ96688.1 - 0.0015 18.6 0.0 0.0032 17.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ96688.1 - 0.0023 17.5 0.1 1.5 8.3 0.1 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CDJ96688.1 - 0.0027 18.1 1.7 0.005 17.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 CDJ96688.1 - 0.0034 16.9 0.0 0.0076 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 CDJ96688.1 - 0.012 15.5 0.1 0.22 11.4 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase Roc PF08477.13 CDJ96688.1 - 0.017 15.3 0.0 0.04 14.1 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Microtub_bd PF16796.5 CDJ96688.1 - 0.041 13.8 0.0 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 Microtubule binding PduV-EutP PF10662.9 CDJ96688.1 - 0.15 11.8 0.1 0.59 9.9 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 CDJ96688.1 - 0.17 12.4 0.8 0.48 10.9 0.1 2.2 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 CDJ96688.1 - 2.5 8.6 13.0 2.2 8.8 0.1 2.6 2 1 0 2 2 2 0 AAA domain UbiA PF01040.18 CDJ96689.1 - 1.5e-44 152.2 12.4 1.9e-44 151.9 12.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family CPSase_L_D2 PF02786.17 CDJ96690.1 - 1.8e-73 246.6 0.0 2.9e-73 245.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 CDJ96690.1 - 1.6e-34 118.2 0.0 3.9e-34 117.0 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain PCC_BT PF18140.1 CDJ96690.1 - 7.6e-23 81.2 1.1 1.3e-22 80.5 0.1 1.9 2 0 0 2 2 2 1 Propionyl-coenzyme A carboxylase BT domain Biotin_lipoyl PF00364.22 CDJ96690.1 - 1.4e-16 60.1 6.5 3.3e-16 58.9 6.5 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CDJ96690.1 - 5.9e-07 29.2 2.2 0.0058 16.4 0.0 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 CDJ96690.1 - 1.6e-06 27.8 0.0 3.7e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CDJ96690.1 - 0.00014 21.5 0.0 0.00026 20.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.6 CDJ96690.1 - 0.00064 19.6 2.7 0.0021 18.0 2.7 1.9 1 1 0 1 1 1 1 RnfC Barrel sandwich hybrid domain RimK PF08443.11 CDJ96690.1 - 0.001 18.7 0.0 0.013 15.1 0.0 2.5 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_D23 PF16576.5 CDJ96690.1 - 0.013 14.7 1.2 0.57 9.4 0.1 2.2 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 CDJ96690.1 - 0.022 15.5 2.5 0.57 10.9 0.1 2.9 3 0 0 3 3 3 0 HlyD family secretion protein ATP-grasp_3 PF02655.14 CDJ96690.1 - 0.022 14.8 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Biotin_carb_N PF00289.22 CDJ96691.1 - 6.2e-45 152.3 0.1 8.5e-45 151.8 0.1 1.2 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Patched PF02460.18 CDJ96692.1 - 3.9e-14 51.7 12.7 4.3e-14 51.6 12.7 1.0 1 0 0 1 1 1 1 Patched family Patched PF02460.18 CDJ96693.1 - 3e-206 687.2 15.4 3.7e-206 686.9 15.4 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 CDJ96693.1 - 1.4e-39 135.4 18.4 9.8e-39 132.6 4.9 2.6 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Transposase_1 PF01359.18 CDJ96694.1 - 6.1e-28 96.5 0.2 2.2e-27 94.7 0.2 2.0 2 0 0 2 2 2 1 Transposase (partial DDE domain) HTH_48 PF17906.1 CDJ96694.1 - 2e-13 50.2 0.1 7.7e-13 48.4 0.0 1.9 2 0 0 2 2 2 1 HTH domain in Mos1 transposase DDE_3 PF13358.6 CDJ96694.1 - 1.6e-07 31.2 0.1 2.5e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 CDJ96694.1 - 0.0022 18.2 0.2 0.0079 16.4 0.1 2.0 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 CDJ96694.1 - 0.0042 17.7 0.5 0.0042 17.7 0.5 2.9 3 1 1 4 4 4 1 Homeodomain-like domain HTH_AsnC-type PF13404.6 CDJ96694.1 - 0.0049 16.7 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_29 PF13551.6 CDJ96694.1 - 0.012 15.6 0.1 0.034 14.2 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn helix HTH_23 PF13384.6 CDJ96694.1 - 0.022 14.5 0.9 0.47 10.3 0.1 3.1 3 0 0 3 3 3 0 Homeodomain-like domain HTH_24 PF13412.6 CDJ96694.1 - 0.15 11.6 0.1 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding IF2_N PF04760.15 CDJ96694.1 - 0.16 11.9 0.0 0.43 10.4 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Zip PF02535.22 CDJ96695.1 - 1.1e-48 166.2 9.7 1.1e-38 133.4 1.9 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter Patched PF02460.18 CDJ96696.1 - 5.5e-90 302.6 0.5 1.3e-79 268.3 3.1 2.2 1 1 1 2 2 2 2 Patched family Sterol-sensing PF12349.8 CDJ96696.1 - 9.6e-37 126.2 8.8 2.3e-36 125.0 8.8 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 CDJ96696.1 - 0.00033 19.7 3.3 0.00056 18.9 3.3 1.3 1 0 0 1 1 1 1 MMPL family SPT_ssu-like PF11779.8 CDJ96697.1 - 0.12 12.0 2.3 0.18 11.4 2.3 1.2 1 0 0 1 1 1 0 Small subunit of serine palmitoyltransferase-like TauE PF01925.19 CDJ96699.1 - 4.9e-10 39.4 12.2 4.9e-10 39.4 12.2 1.9 1 1 1 2 2 2 2 Sulfite exporter TauE/SafE LRR_8 PF13855.6 CDJ96700.1 - 4.5e-22 77.6 11.1 2.4e-09 36.8 1.6 3.9 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CDJ96700.1 - 1.6e-21 76.0 8.7 3.3e-06 27.3 0.3 4.8 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CDJ96700.1 - 2.6e-10 39.5 16.3 0.01 15.9 0.1 7.8 7 0 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.33 CDJ96700.1 - 1.2e-07 31.3 7.3 6 7.8 0.0 7.1 7 0 0 7 7 7 2 Leucine Rich Repeat B3_4 PF03483.17 CDJ96700.1 - 5e-06 26.3 0.0 1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain RNA_pol_Rpc82 PF05645.13 CDJ96700.1 - 0.013 15.3 0.4 0.033 13.9 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 Pkinase_Tyr PF07714.17 CDJ96701.1 - 2.3e-44 151.6 0.0 4e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ96701.1 - 8.3e-39 133.5 0.0 1.2e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ribosomal_L17 PF01196.19 CDJ96701.1 - 6.4e-10 39.8 0.0 1.4e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L17 C1_1 PF00130.22 CDJ96701.1 - 0.00051 19.9 10.5 0.00086 19.1 10.5 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SAM_KSR1 PF13543.6 CDJ96701.1 - 0.0056 16.8 0.1 0.023 14.9 0.0 2.0 3 0 0 3 3 3 1 SAM like domain present in kinase suppressor RAS 1 Kinase-like PF14531.6 CDJ96701.1 - 0.02 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 CDJ96701.1 - 0.17 11.2 0.1 0.34 10.2 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1518 PF07469.12 CDJ96701.1 - 0.98 9.9 14.7 0.063 13.7 8.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1518) PAN_1 PF00024.26 CDJ96702.1 - 3e-14 52.8 8.6 1.6e-09 37.6 0.6 2.3 2 0 0 2 2 2 2 PAN domain TPR_2 PF07719.17 CDJ96703.1 - 1.5e-21 74.7 19.4 1.9e-05 24.4 0.0 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ96703.1 - 1.9e-17 62.4 6.5 0.0045 17.7 0.0 6.9 4 1 3 7 7 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ96703.1 - 2.5e-15 55.3 11.2 0.00058 19.9 0.3 7.2 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ96703.1 - 1.2e-14 53.3 19.7 0.00014 21.5 0.0 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ96703.1 - 1.9e-14 53.9 7.0 9e-07 29.3 0.0 5.6 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ96703.1 - 1.2e-10 41.9 5.2 1.3e-05 25.7 0.0 5.1 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ96703.1 - 6e-09 35.7 1.3 0.00025 21.2 0.0 5.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ96703.1 - 3e-08 33.8 9.8 0.00011 22.4 0.1 5.8 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ96703.1 - 3.4e-08 33.6 1.9 0.71 10.6 0.0 5.7 5 0 0 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ96703.1 - 2e-07 31.1 9.2 0.00012 22.3 1.6 5.5 5 2 1 6 6 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CDJ96703.1 - 7e-07 28.8 0.0 0.013 15.2 0.0 4.4 3 1 1 4 4 4 1 TPR repeat TPR_15 PF13429.6 CDJ96703.1 - 6.9e-06 25.5 4.1 0.0037 16.5 0.3 4.2 2 1 3 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ96703.1 - 1.2e-05 25.3 3.4 0.0044 17.1 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.10 CDJ96703.1 - 2.1e-05 23.8 2.0 9.7e-05 21.5 2.0 1.9 1 1 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) PPR PF01535.20 CDJ96703.1 - 0.0002 21.4 4.2 0.12 12.7 0.1 4.2 5 0 0 5 5 2 2 PPR repeat TPR_7 PF13176.6 CDJ96703.1 - 0.0003 20.6 9.9 16 5.8 0.1 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 CDJ96703.1 - 0.00039 19.8 0.2 2.5 7.6 0.0 3.9 4 0 0 4 4 4 1 SHNi-TPR SPOB_a PF14689.6 CDJ96703.1 - 0.0037 16.9 2.2 8.7 6.1 0.0 4.3 4 0 0 4 4 4 0 Sensor_kinase_SpoOB-type, alpha-helical domain DUF4919 PF16266.5 CDJ96703.1 - 0.0073 16.3 0.0 1.1 9.2 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4919) Fis1_TPR_C PF14853.6 CDJ96703.1 - 0.013 15.5 5.3 13 6.0 0.1 5.1 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Clathrin PF00637.20 CDJ96703.1 - 0.038 13.9 0.0 0.038 13.9 0.0 3.5 3 2 1 4 4 4 0 Region in Clathrin and VPS TPR_10 PF13374.6 CDJ96703.1 - 0.054 13.4 0.2 0.054 13.4 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Vpu PF00558.19 CDJ96703.1 - 0.062 13.1 0.1 3.6 7.4 0.0 2.7 2 0 0 2 2 2 0 Vpu protein Wzy_C_2 PF11846.8 CDJ96703.1 - 0.08 12.9 0.1 0.53 10.2 0.0 2.4 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal V-ATPase_H_C PF11698.8 CDJ96703.1 - 0.087 12.9 0.2 1.1 9.4 0.1 2.6 2 0 0 2 2 2 0 V-ATPase subunit H TBP PF00352.21 CDJ96704.1 - 1.1e-64 214.4 0.1 5.2e-32 109.6 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 CDJ96704.1 - 0.00014 21.9 0.0 0.31 11.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Hexapep PF00132.24 CDJ96704.1 - 0.0015 18.1 0.0 0.0052 16.5 0.0 2.0 1 0 0 1 1 1 1 Bacterial transferase hexapeptide (six repeats) CBF PF03914.17 CDJ96705.1 - 9.9e-22 77.8 0.3 9.9e-22 77.8 0.3 2.8 3 0 0 3 3 3 1 CBF/Mak21 family Abhydrolase_6 PF12697.7 CDJ96706.1 - 0.029 15.0 0.0 0.039 14.5 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF915 PF06028.11 CDJ96706.1 - 0.072 12.4 0.0 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) zf-RING_2 PF13639.6 CDJ96707.1 - 6.9e-13 48.7 6.9 6.9e-13 48.7 6.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 CDJ96707.1 - 3.8e-10 39.3 0.9 3.8e-10 39.3 0.9 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CDJ96707.1 - 3.2e-09 36.5 6.7 3.2e-09 36.5 6.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDJ96707.1 - 1.5e-08 34.7 3.2 4e-08 33.4 3.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDJ96707.1 - 5e-07 29.5 5.1 5e-07 29.5 5.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ96707.1 - 1.9e-06 27.7 3.3 1.9e-06 27.7 3.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDJ96707.1 - 4.3e-05 23.4 8.4 4.5e-05 23.4 4.7 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDJ96707.1 - 0.00025 20.8 3.6 0.00025 20.8 3.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CDJ96707.1 - 0.0015 18.1 3.0 0.0015 18.1 3.0 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CDJ96707.1 - 0.0021 17.9 4.3 0.0021 17.9 4.3 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CDJ96707.1 - 0.0021 18.1 2.4 0.0053 16.8 2.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger CrgA PF06781.12 CDJ96707.1 - 0.0071 16.4 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Cell division protein CrgA PspB PF06667.12 CDJ96707.1 - 0.015 15.4 0.3 0.031 14.3 0.3 1.5 1 0 0 1 1 1 0 Phage shock protein B YuiB PF14068.6 CDJ96707.1 - 0.067 13.8 0.5 0.13 12.8 0.0 1.7 2 0 0 2 2 1 0 Putative membrane protein zf-C3H2C3 PF17122.5 CDJ96707.1 - 0.12 12.4 3.6 0.37 10.9 3.6 1.8 1 0 0 1 1 1 0 Zinc-finger zf-RING_9 PF13901.6 CDJ96707.1 - 0.59 10.1 5.4 0.098 12.6 1.3 1.7 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon zinc_ribbon_16 PF17034.5 CDJ96707.1 - 1.5 9.0 4.7 0.29 11.3 0.7 1.9 2 0 0 2 2 1 0 Zinc-ribbon like family zf-C3HC4_4 PF15227.6 CDJ96707.1 - 2.6 8.3 8.9 7.5 6.8 3.1 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING PHD PF00628.29 CDJ96707.1 - 3.7 7.5 12.2 0.98 9.4 4.7 2.4 2 0 0 2 2 2 0 PHD-finger Pox_A9 PF04835.12 CDJ96708.1 - 0.66 10.2 0.1 0.66 10.2 0.1 2.8 3 1 0 3 3 3 0 A9 protein conserved region CDC45 PF02724.14 CDJ96709.1 - 3.3e-78 263.6 10.7 7.8e-56 189.7 8.4 3.0 1 1 1 2 2 2 2 CDC45-like protein SGS PF05002.15 CDJ96710.1 - 9.9e-26 89.7 1.2 1.6e-25 89.0 1.2 1.3 1 0 0 1 1 1 1 SGS domain CS PF04969.16 CDJ96710.1 - 4.9e-10 40.3 0.1 7.4e-10 39.7 0.1 1.3 1 0 0 1 1 1 1 CS domain Proteasome PF00227.26 CDJ96711.1 - 1.3e-57 194.3 0.0 2.2e-57 193.6 0.0 1.3 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ96711.1 - 7.2e-10 38.4 0.0 1.2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GTP_EFTU PF00009.27 CDJ96712.1 - 2.1e-56 190.5 0.0 3.2e-56 190.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDJ96712.1 - 4.2e-06 26.8 0.1 9.4e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CDJ96712.1 - 0.00025 21.4 0.0 0.00076 19.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 FeoB_N PF02421.18 CDJ96712.1 - 0.0003 20.4 0.0 0.0011 18.5 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 CDJ96712.1 - 0.023 14.1 0.1 0.07 12.6 0.1 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit cobW PF02492.19 CDJ96712.1 - 0.049 13.2 0.2 0.92 9.1 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.16 CDJ96712.1 - 0.099 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 AIG1 family DUF229 PF02995.17 CDJ96714.1 - 9.3e-13 47.6 2.6 9.9e-13 47.5 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF229 PF02995.17 CDJ96715.1 - 1.7e-09 36.8 0.2 1.9e-09 36.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Tenui_N PF05733.11 CDJ96715.1 - 0.068 12.7 0.0 0.081 12.4 0.0 1.1 1 0 0 1 1 1 0 Tenuivirus/Phlebovirus nucleocapsid protein RVT_1 PF00078.27 CDJ96716.1 - 2.3e-37 128.7 0.0 4.5e-37 127.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDJ96716.1 - 7.4e-05 22.6 0.3 0.0002 21.2 0.0 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ96716.1 - 0.00066 19.3 0.0 0.0025 17.4 0.0 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family ERp29 PF07749.12 CDJ96716.1 - 0.24 12.3 1.6 32 5.5 0.1 2.7 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain FHIPEP PF00771.20 CDJ96716.1 - 0.27 9.6 0.2 0.4 9.1 0.2 1.1 1 0 0 1 1 1 0 FHIPEP family 7tm_1 PF00001.21 CDJ96719.1 - 2.3e-18 66.4 3.8 2.9e-18 66.2 3.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Glyco_transf_10 PF00852.19 CDJ96721.1 - 1.6e-52 177.8 2.6 2.4e-52 177.2 2.6 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CDJ96721.1 - 1.5e-08 35.1 0.0 4.2e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal TraF PF13728.6 CDJ96721.1 - 0.032 14.1 1.1 1.8 8.3 0.4 2.2 1 1 0 2 2 2 0 F plasmid transfer operon protein Glyco_transf_10 PF00852.19 CDJ96722.1 - 3.4e-58 196.3 0.5 3.9e-58 196.1 0.5 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term TPR_2 PF07719.17 CDJ96723.1 - 1e-06 28.4 1.6 0.16 12.1 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ96723.1 - 2.6e-05 24.5 2.6 1.6 9.6 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ96723.1 - 7.8e-05 23.2 4.8 0.65 11.0 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ96723.1 - 0.00013 22.4 0.1 0.47 11.0 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ96723.1 - 0.00022 20.9 0.1 2.6 8.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ96723.1 - 0.0015 18.6 0.0 0.55 10.6 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ96723.1 - 0.0017 18.9 1.1 0.0017 18.9 1.1 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat AA_kinase PF00696.28 CDJ96724.1 - 2e-17 63.6 0.0 2.8e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family AAA_3 PF07726.11 CDJ96725.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RVT_1 PF00078.27 CDJ96727.1 - 5.7e-11 42.4 0.0 9.9e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF273 PF03314.14 CDJ96728.1 - 2.4e-33 115.6 2.7 2.3e-23 82.9 2.2 2.0 1 1 1 2 2 2 2 Protein of unknown function, DUF273 Glyco_tranf_2_4 PF13704.6 CDJ96728.1 - 0.01 16.3 0.1 0.022 15.3 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Peptidase_C1 PF00112.23 CDJ96729.1 - 7.1e-38 130.9 3.8 4.6e-21 75.9 0.9 2.1 1 1 1 2 2 2 2 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ96729.1 - 0.038 12.8 2.2 0.063 12.1 2.2 1.2 1 0 0 1 1 1 0 Peptidase C1-like family Trp_oprn_chp PF09534.10 CDJ96729.1 - 0.048 13.5 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3810 PF12725.7 CDJ96729.1 - 0.074 12.4 0.3 0.14 11.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF3040 PF11239.8 CDJ96729.1 - 0.077 13.3 0.2 0.15 12.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF872 PF05915.12 CDJ96729.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF2116 PF09889.9 CDJ96729.1 - 0.3 11.1 0.1 0.3 11.1 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Ribosomal_L37 PF08561.10 CDJ96730.1 - 0.00052 20.5 0.1 0.00052 20.5 0.1 3.6 3 1 0 3 3 3 1 Mitochondrial ribosomal protein L37 GTP_EFTU PF00009.27 CDJ96731.1 - 2.1e-64 216.6 0.1 3.1e-64 216.1 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CDJ96731.1 - 8.9e-34 115.9 0.1 5.3e-33 113.4 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CDJ96731.1 - 2.1e-22 78.9 0.0 5.8e-22 77.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CDJ96731.1 - 1.5e-13 50.6 0.0 3.7e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CDJ96731.1 - 2.3e-11 43.9 0.2 8.5e-11 42.1 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDJ96731.1 - 1.1e-05 25.5 0.1 2.5e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PK PF00224.21 CDJ96732.1 - 1.5e-157 523.9 5.4 1.9e-157 523.6 5.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CDJ96732.1 - 1.4e-28 99.5 0.0 4.6e-28 97.8 0.0 2.0 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CDJ96732.1 - 5.3e-06 25.7 0.7 1.3e-05 24.4 0.7 1.7 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family tRNA_anti-codon PF01336.25 CDJ96734.1 - 0.12 12.4 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain PK PF00224.21 CDJ96735.1 - 5.6e-162 538.5 4.0 7.3e-162 538.1 4.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CDJ96735.1 - 2.9e-27 95.2 0.3 7e-27 94.0 0.3 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CDJ96735.1 - 0.00012 21.2 0.3 0.00034 19.8 0.2 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Ank_2 PF12796.7 CDJ96736.1 - 2.9e-47 159.2 21.9 1.8e-11 44.5 0.1 6.1 2 1 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ96736.1 - 6.2e-33 112.4 20.3 6.1e-06 26.4 0.7 9.2 4 3 5 9 9 9 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDJ96736.1 - 6.1e-32 109.6 14.9 1e-05 25.9 0.0 8.0 7 1 1 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ96736.1 - 7.6e-32 105.8 11.1 0.00059 20.1 0.0 10.9 11 0 0 11 11 10 7 Ankyrin repeat Ank PF00023.30 CDJ96736.1 - 5.9e-26 89.7 16.1 0.00018 21.8 0.1 8.6 8 1 1 9 9 8 6 Ankyrin repeat LRR_8 PF13855.6 CDJ96736.1 - 5.6e-20 70.9 7.6 1.7e-11 43.7 1.6 2.9 3 0 0 3 3 2 2 Leucine rich repeat LRR_4 PF12799.7 CDJ96736.1 - 3.1e-16 59.2 7.2 2.1e-07 31.1 1.4 4.2 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDJ96736.1 - 0.00012 22.1 5.2 4.9 8.1 0.0 5.9 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_9 PF14580.6 CDJ96736.1 - 0.02 14.4 0.3 0.043 13.3 0.3 1.5 1 0 0 1 1 1 0 Leucine-rich repeat DUF3447 PF11929.8 CDJ96736.1 - 0.025 14.5 0.1 16 5.6 0.1 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF3447) LRR_6 PF13516.6 CDJ96736.1 - 0.049 13.7 12.2 8.2 6.8 0.1 5.2 5 0 0 5 5 5 0 Leucine Rich repeat SIP PF04954.13 CDJ96736.1 - 0.11 13.0 0.1 4.1 7.9 0.0 2.5 1 1 1 2 2 2 0 Siderophore-interacting protein ABC2_membrane_3 PF12698.7 CDJ96737.1 - 2.1e-06 27.1 10.8 2.1e-06 27.1 10.8 2.4 2 1 0 2 2 2 1 ABC-2 family transporter protein Glyco_transf_43 PF03360.16 CDJ96738.1 - 1.6e-40 139.2 0.0 2e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 Sdh_cyt PF01127.22 CDJ96738.1 - 0.091 12.8 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit ShK PF01549.24 CDJ96739.1 - 7.7e-09 35.9 4.4 1.1e-08 35.5 4.4 1.2 1 0 0 1 1 1 1 ShK domain-like PLAC PF08686.11 CDJ96739.1 - 0.0057 17.4 0.7 0.017 15.9 0.7 1.8 1 1 0 1 1 1 1 PLAC (protease and lacunin) domain ShK PF01549.24 CDJ96740.1 - 7.7e-09 35.9 4.4 1.1e-08 35.5 4.4 1.2 1 0 0 1 1 1 1 ShK domain-like PLAC PF08686.11 CDJ96740.1 - 0.0057 17.4 0.7 0.017 15.9 0.7 1.8 1 1 0 1 1 1 1 PLAC (protease and lacunin) domain SCVP PF17619.2 CDJ96742.1 - 8.4e-13 49.0 0.8 1e-12 48.7 0.8 1.1 1 0 0 1 1 1 1 Secreted clade V proteins MatP PF06303.12 CDJ96742.1 - 0.14 12.7 0.0 0.25 11.9 0.0 1.4 1 1 0 1 1 1 0 MatP N-terminal domain Motile_Sperm PF00635.26 CDJ96744.1 - 1.7e-11 43.9 0.0 2e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 MSP (Major sperm protein) domain p450 PF00067.22 CDJ96745.1 - 1e-108 364.0 0.0 1.3e-108 363.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 rve_3 PF13683.6 CDJ96746.1 - 0.039 13.7 0.0 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Plasmodium_Vir PF05795.11 CDJ96747.1 - 0.058 12.8 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SCIMP PF15050.6 CDJ96747.1 - 0.08 13.4 0.9 2.4 8.6 0.1 2.1 1 1 1 2 2 2 0 SCIMP protein CAP_N PF01213.19 CDJ96748.1 - 2.1 7.8 3.4 4.1 6.8 3.4 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Rhodanese PF00581.20 CDJ96749.1 - 4.2e-08 33.7 0.0 8.9e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Neuregulin PF02158.15 CDJ96749.1 - 0.04 13.3 9.7 0.1 11.9 9.1 1.8 2 0 0 2 2 2 0 Neuregulin intracellular region SPG4 PF17325.2 CDJ96750.1 - 0.77 10.9 4.2 1.4 10.1 0.0 3.0 2 1 0 2 2 2 0 Stationary phase protein 4 Peptidase_S10 PF00450.22 CDJ96751.1 - 8.7e-36 124.2 0.8 9.6e-36 124.1 0.8 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Kunitz_BPTI PF00014.23 CDJ96752.1 - 1.6e-25 89.1 41.6 1.2e-14 54.2 14.8 2.8 3 0 0 3 3 3 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Peptidase_S10 PF00450.22 CDJ96752.1 - 3.8e-23 82.6 2.2 3.8e-23 82.6 2.2 1.6 2 0 0 2 2 2 1 Serine carboxypeptidase Mucin PF01456.17 CDJ96752.1 - 3.8 7.5 20.7 0.12 12.3 13.7 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein 3-HAO PF06052.12 CDJ96753.1 - 1.1e-68 229.6 0.0 1.7e-68 229.0 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 CDJ96753.1 - 5.9e-05 22.7 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain RNase_H PF00075.24 CDJ96754.1 - 1.2e-10 41.7 0.0 3.6e-10 40.2 0.0 1.7 1 1 0 1 1 1 1 RNase H DUF1348 PF07080.11 CDJ96754.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1348) Homeodomain PF00046.29 CDJ96755.1 - 1.1e-21 76.4 3.4 8.7e-21 73.5 3.5 2.3 2 0 0 2 2 2 1 Homeodomain CAP PF00188.26 CDJ96755.1 - 1.2e-16 61.6 0.3 1.2e-16 61.6 0.3 2.1 3 0 0 3 3 3 1 Cysteine-rich secretory protein family CAP PF00188.26 CDJ96756.1 - 2.2e-12 47.9 2.5 2.8e-12 47.6 2.5 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ96756.1 - 0.016 15.5 0.5 0.033 14.5 0.4 1.7 1 1 0 1 1 1 0 Ancylostoma-associated secreted protein related RPN5_C PF18098.1 CDJ96756.1 - 0.046 13.8 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN5 C-terminal domain MCM_lid PF17855.1 CDJ96759.1 - 1.3e-15 57.6 1.1 4.7e-14 52.6 0.9 2.5 1 1 0 1 1 1 1 MCM AAA-lid domain Neur_chan_LBD PF02931.23 CDJ96760.1 - 1.1e-18 67.5 0.0 2.9e-15 56.3 0.0 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ96760.1 - 6e-11 42.9 0.1 1e-10 42.1 0.1 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region F-box PF00646.33 CDJ96761.1 - 1.8e-09 37.3 1.2 9.1e-09 35.0 0.1 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CDJ96761.1 - 2.3e-07 30.6 0.1 5.9e-07 29.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like Unstab_antitox PF09720.10 CDJ96761.1 - 0.11 12.6 0.6 0.32 11.1 0.1 1.9 2 0 0 2 2 2 0 Putative addiction module component COesterase PF00135.28 CDJ96762.1 - 8.1e-12 44.8 0.1 8.6e-12 44.7 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family MSA_2 PF00985.17 CDJ96763.1 - 0.13 12.6 5.8 0.18 12.1 5.8 1.3 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family DUF3827 PF12877.7 CDJ96763.1 - 0.39 9.0 8.0 0.48 8.7 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Neur_chan_memb PF02932.16 CDJ96763.1 - 2 8.4 4.1 2.4 8.2 4.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4551 PF15087.6 CDJ96763.1 - 4.7 5.9 6.7 5.2 5.8 6.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Presenilin PF01080.17 CDJ96763.1 - 6.3 5.5 8.0 7.3 5.2 8.0 1.1 1 0 0 1 1 1 0 Presenilin Minor_capsid_1 PF10665.9 CDJ96764.1 - 0.043 14.0 0.6 0.35 11.1 0.2 2.2 1 1 1 2 2 2 0 Minor capsid protein Plasmodium_Vir PF05795.11 CDJ96764.1 - 0.26 10.7 4.1 0.31 10.4 4.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FUSC PF04632.12 CDJ96764.1 - 0.89 8.0 1.5 1.1 7.7 1.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Hid1 PF12722.7 CDJ96764.1 - 9.4 4.2 7.2 11 4.0 7.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ion_trans_2 PF07885.16 CDJ96765.1 - 7e-14 51.5 0.3 9e-14 51.2 0.3 1.2 1 0 0 1 1 1 1 Ion channel L6_membrane PF05805.12 CDJ96765.1 - 0.052 13.1 0.1 0.064 12.8 0.1 1.1 1 0 0 1 1 1 0 L6 membrane protein CAP PF00188.26 CDJ96766.1 - 2.7e-19 70.2 0.5 3.7e-19 69.8 0.5 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ96766.1 - 0.016 15.5 2.0 0.09 13.1 2.0 2.1 1 1 0 1 1 1 0 Ancylostoma-associated secreted protein related CAP PF00188.26 CDJ96767.1 - 1.4e-14 55.0 0.1 1.4e-14 55.0 0.1 3.1 3 1 0 3 3 3 1 Cysteine-rich secretory protein family HTH_Bact PF18768.1 CDJ96767.1 - 0.17 11.5 0.0 0.44 10.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix bacterial domain CAP PF00188.26 CDJ96769.1 - 1e-15 58.7 0.2 1.2e-15 58.4 0.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ECM11 PF15463.6 CDJ96770.1 - 0.001 19.6 1.3 0.0013 19.3 1.3 1.1 1 0 0 1 1 1 1 Extracellular mutant protein 11 DUF4709 PF15821.5 CDJ96770.1 - 0.039 14.2 0.2 0.062 13.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) Peptidase_S49_N PF08496.10 CDJ96770.1 - 0.053 13.6 0.4 0.066 13.3 0.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ThylakoidFormat PF11264.8 CDJ96770.1 - 0.064 12.9 0.3 0.079 12.6 0.3 1.1 1 0 0 1 1 1 0 Thylakoid formation protein DUF2586 PF10758.9 CDJ96770.1 - 0.096 11.8 0.0 0.11 11.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2586) HflK_N PF12221.8 CDJ96770.1 - 0.17 11.9 0.2 2 8.5 0.2 2.5 2 1 0 2 2 2 0 Bacterial membrane protein N terminal CdvA PF18822.1 CDJ96770.1 - 0.18 11.6 2.9 2.8 7.8 1.1 2.0 1 1 1 2 2 2 0 CdvA-like coiled-coil domain ChaC PF04752.12 CDJ96771.1 - 1.9e-36 125.8 0.0 2.1e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 CDJ96771.1 - 0.059 14.0 0.0 0.081 13.5 0.0 1.2 1 0 0 1 1 1 0 Gamma-glutamyl cyclotransferase, AIG2-like PIF2 PF04631.12 CDJ96771.1 - 0.069 12.0 0.0 0.098 11.5 0.0 1.2 1 0 0 1 1 1 0 Per os infectivity factor 2 DDE_3 PF13358.6 CDJ96772.1 - 3.8e-06 26.7 0.2 5.7e-06 26.2 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease EGF PF00008.27 CDJ96773.1 - 1.5e-20 73.1 39.9 2.1e-07 31.1 10.6 3.9 3 0 0 3 3 3 3 EGF-like domain Kunitz_BPTI PF00014.23 CDJ96773.1 - 3e-13 49.8 23.3 5e-08 33.1 8.7 3.5 4 0 0 4 4 4 2 Kunitz/Bovine pancreatic trypsin inhibitor domain hEGF PF12661.7 CDJ96773.1 - 1.8e-05 25.2 29.9 0.0065 17.1 5.1 4.7 4 1 0 4 4 4 3 Human growth factor-like EGF CBP4 PF07960.11 CDJ96773.1 - 0.34 10.8 8.2 0.59 10.0 8.2 1.3 1 0 0 1 1 1 0 CBP4 EGF_2 PF07974.13 CDJ96773.1 - 1.4 9.3 49.2 0.46 10.9 6.6 4.2 4 1 0 4 4 4 0 EGF-like domain EGF_3 PF12947.7 CDJ96773.1 - 2.1 8.6 45.2 1.8 8.8 10.1 3.9 3 0 0 3 3 3 0 EGF domain Motile_Sperm PF00635.26 CDJ96774.1 - 1.4e-08 34.5 0.3 2.1e-08 34.0 0.3 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Amidase PF01425.21 CDJ96775.1 - 6.6e-96 322.0 0.0 7.9e-96 321.7 0.0 1.1 1 0 0 1 1 1 1 Amidase Aminotran_1_2 PF00155.21 CDJ96778.1 - 3.6e-82 276.5 0.0 4.1e-82 276.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Sina PF03145.16 CDJ96780.1 - 1.2e-78 263.7 0.4 1.3e-78 263.5 0.4 1.0 1 0 0 1 1 1 1 Seven in absentia protein family zf-TRAF PF02176.18 CDJ96780.1 - 0.25 12.1 6.9 13 6.5 0.1 2.9 3 0 0 3 3 3 0 TRAF-type zinc finger Beta_helix PF13229.6 CDJ96782.1 - 1.9e-102 339.7 54.9 4.8e-28 98.0 9.6 5.2 1 1 5 6 6 6 5 Right handed beta helix region NosD PF05048.13 CDJ96782.1 - 5e-44 150.4 13.1 2.6e-16 59.6 1.2 4.6 1 1 4 5 5 5 4 Periplasmic copper-binding protein (NosD) F-box-like PF12937.7 CDJ96782.1 - 7.5e-11 41.8 0.0 1.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like zf-UBR PF02207.20 CDJ96782.1 - 4.4e-08 33.2 13.8 1.2e-07 31.8 13.8 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) F-box PF00646.33 CDJ96782.1 - 1.1e-05 25.2 0.0 2.5e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain Sugar_tr PF00083.24 CDJ96783.1 - 3e-27 95.6 15.0 5.4e-27 94.8 15.0 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ96783.1 - 2.9e-23 82.4 14.5 3.9e-19 68.8 9.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CDJ96783.1 - 0.00041 19.0 4.0 0.00041 19.0 4.0 3.6 5 0 0 5 5 5 1 MFS/sugar transport protein BK_channel_a PF03493.18 CDJ96784.1 - 4.3e-18 65.3 0.0 8.8e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 CDJ96784.1 - 6.3e-18 64.9 17.5 6.3e-18 64.9 17.5 1.8 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.16 CDJ96784.1 - 6.8e-14 51.6 6.7 6.8e-14 51.6 6.7 3.1 4 0 0 4 4 4 1 Ion channel PGG PF13962.6 CDJ96784.1 - 0.016 15.0 0.0 1.6 8.5 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function Lig_chan PF00060.26 CDJ96784.1 - 0.14 12.0 0.1 0.14 12.0 0.1 2.7 2 1 0 2 2 2 0 Ligand-gated ion channel TrkA_N PF02254.18 CDJ96784.1 - 0.18 12.1 0.0 0.32 11.3 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain EF-hand_1 PF00036.32 CDJ96786.1 - 4.1e-35 116.7 18.2 7e-09 34.6 1.9 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ96786.1 - 3.4e-30 104.3 5.7 2.5e-14 53.5 2.8 2.8 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ96786.1 - 1.6e-25 88.7 17.2 8.6e-09 35.1 0.0 4.3 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CDJ96786.1 - 1.6e-25 86.8 8.1 2.7e-08 33.1 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CDJ96786.1 - 1.1e-15 56.4 10.6 7.4e-06 25.2 0.4 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CDJ96786.1 - 1.2e-11 44.7 0.1 8e-05 22.9 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CDJ96786.1 - 7.4e-10 38.7 3.5 2.2e-05 24.4 0.2 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CDJ96786.1 - 3.4e-05 24.1 1.2 0.18 12.1 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 CDJ96786.1 - 0.00066 19.7 8.6 0.16 12.0 0.2 3.5 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 CDJ96786.1 - 0.014 16.3 0.1 1 10.3 0.1 2.1 1 1 1 2 2 2 0 EF-hand domain Caleosin PF05042.13 CDJ96786.1 - 0.017 15.1 1.2 12 5.7 0.0 3.2 1 1 2 3 3 3 0 Caleosin related protein DUF3016 PF11454.8 CDJ96786.1 - 0.018 14.8 0.0 0.024 14.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3016) EFhand_Ca_insen PF08726.10 CDJ96786.1 - 0.019 15.0 0.8 0.019 15.0 0.8 1.8 2 0 0 2 2 2 0 Ca2+ insensitive EF hand DUF1642 PF07852.11 CDJ96786.1 - 0.026 15.1 0.7 1.7 9.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1642) Dockerin_1 PF00404.18 CDJ96786.1 - 0.1 12.8 0.4 15 5.9 0.1 3.1 1 1 2 3 3 3 0 Dockerin type I domain Sec7 PF01369.20 CDJ96787.1 - 4.1e-49 166.7 0.2 5.8e-49 166.2 0.2 1.2 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.5 CDJ96787.1 - 6e-47 159.1 0.1 1.1e-46 158.2 0.1 1.5 1 0 0 1 1 1 1 PH domain IQ PF00612.27 CDJ96787.1 - 0.35 10.8 2.1 1.1 9.2 2.1 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF1768 PF08719.11 CDJ96789.1 - 2.8e-31 108.9 0.7 4.5e-31 108.3 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Glyco_hydro_47 PF01532.20 CDJ96790.1 - 2.8e-145 484.7 1.0 3.4e-145 484.4 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ASD1 PF08688.10 CDJ96790.1 - 0.64 10.4 2.3 32 4.9 0.0 2.2 2 0 0 2 2 2 0 Apx/Shroom domain ASD1 DUF4807 PF16065.5 CDJ96791.1 - 1.3e-37 128.3 0.7 2e-37 127.6 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4807) CBS PF00571.28 CDJ96792.1 - 1.1e-32 112.2 5.4 7.9e-09 35.8 0.5 4.4 4 0 0 4 4 4 4 CBS domain SH3_9 PF14604.6 CDJ96794.1 - 4.1e-18 65.0 0.3 2.4e-17 62.5 0.5 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 CDJ96794.1 - 9.4e-15 54.0 0.1 1.3e-14 53.5 0.1 1.2 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDJ96794.1 - 9.8e-13 47.6 0.1 3.1e-12 46.0 0.0 1.7 1 1 1 2 2 2 1 Variant SH3 domain AMP-binding PF00501.28 CDJ96795.1 - 2.7e-79 266.8 0.0 3.5e-79 266.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ96795.1 - 0.00032 21.6 0.0 0.00083 20.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain F-box-like PF12937.7 CDJ96796.1 - 1.4e-07 31.3 0.0 4.1e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 CDJ96796.1 - 6.1e-06 26.0 0.1 4.6e-05 23.2 0.1 2.2 1 1 0 1 1 1 1 F-box domain SAM_2 PF07647.17 CDJ96797.1 - 4.1e-10 39.6 0.0 7.2e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CDJ96797.1 - 1.9e-07 31.4 0.2 1.1e-06 28.9 0.0 2.0 1 1 1 2 2 2 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 CDJ96797.1 - 0.033 14.1 0.0 0.097 12.6 0.0 1.8 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain PP2C PF00481.21 CDJ96798.1 - 3.1e-51 174.5 0.0 4.2e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CDJ96798.1 - 1.1e-08 35.0 0.2 2.7e-08 33.7 0.2 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C AMOP PF03782.17 CDJ96799.1 - 4.4e-43 146.8 7.8 1e-42 145.6 7.8 1.7 1 0 0 1 1 1 1 AMOP domain BRICHOS PF04089.14 CDJ96801.1 - 0.00013 22.2 0.2 0.00072 19.8 0.0 2.3 2 0 0 2 2 2 1 BRICHOS domain EpsG PF14897.6 CDJ96801.1 - 0.044 13.1 0.2 0.064 12.5 0.2 1.2 1 0 0 1 1 1 0 EpsG family TTR-52 PF01060.23 CDJ96802.1 - 8.8e-28 96.8 0.0 1.6e-27 96.0 0.0 1.4 2 0 0 2 2 2 1 Transthyretin-like family DUF4198 PF10670.9 CDJ96802.1 - 0.0016 18.9 0.0 0.0027 18.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4198) bMG3 PF11974.8 CDJ96802.1 - 0.0017 18.3 0.0 0.024 14.7 0.0 2.1 1 1 0 1 1 1 1 Bacterial alpha-2-macroglobulin MG3 domain CarboxypepD_reg PF13620.6 CDJ96802.1 - 0.007 16.6 0.1 0.012 15.9 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain MetallophosN PF16371.5 CDJ96802.1 - 0.0091 16.2 0.8 0.58 10.5 0.1 2.7 2 1 1 3 3 3 1 N terminal of Calcineurin-like phosphoesterase Transthyretin PF00576.21 CDJ96802.1 - 0.024 15.3 0.0 0.037 14.7 0.0 1.3 1 0 0 1 1 1 0 HIUase/Transthyretin family SpaA PF17802.1 CDJ96802.1 - 0.083 13.2 0.0 0.12 12.7 0.0 1.5 1 1 0 1 1 1 0 Prealbumin-like fold domain TTR-52 PF01060.23 CDJ96803.1 - 5.2e-30 104.0 0.0 7e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 Transthyretin-like family Transthyretin PF00576.21 CDJ96803.1 - 0.063 14.0 0.0 0.085 13.5 0.0 1.2 1 0 0 1 1 1 0 HIUase/Transthyretin family DUF4198 PF10670.9 CDJ96803.1 - 0.07 13.5 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) Phage_BR0599 PF09356.10 CDJ96803.1 - 0.12 12.7 0.0 0.16 12.3 0.0 1.4 1 1 0 1 1 1 0 Phage conserved hypothetical protein BR0599 ASXH PF13919.6 CDJ96804.1 - 0.0013 18.7 0.0 0.0037 17.3 0.0 1.7 1 0 0 1 1 1 1 Asx homology domain DUF4625 PF15418.6 CDJ96805.1 - 9.7e-07 29.1 0.0 0.52 10.6 0.0 3.5 3 0 0 3 3 3 3 Domain of unknown function (DUF4625) PKD PF00801.20 CDJ96805.1 - 1.6e-06 27.8 4.5 0.018 14.9 0.2 4.8 4 1 0 4 4 4 2 PKD domain Big_9 PF17963.1 CDJ96805.1 - 0.00074 20.2 11.2 0.29 11.9 0.6 4.3 4 0 0 4 4 4 2 Bacterial Ig domain EGF_2 PF07974.13 CDJ96805.1 - 0.00091 19.5 6.7 0.00091 19.5 6.7 2.4 2 0 0 2 2 2 1 EGF-like domain He_PIG PF05345.12 CDJ96805.1 - 0.0057 16.8 1.8 13 6.0 0.0 4.7 4 0 0 4 4 4 1 Putative Ig domain Y_Y_Y PF07495.13 CDJ96805.1 - 0.0074 16.2 0.1 5.2 7.1 0.0 3.9 4 0 0 4 4 4 1 Y_Y_Y domain Cadherin PF00028.17 CDJ96805.1 - 0.01 16.3 0.5 18 5.8 0.0 4.0 5 0 0 5 5 5 0 Cadherin domain DUF5013 PF16405.5 CDJ96805.1 - 0.011 16.0 1.3 53 4.0 0.0 5.0 4 1 2 6 6 6 0 Domain of unknown function (DUF5013) EGF_Tenascin PF18720.1 CDJ96805.1 - 0.049 13.7 1.0 0.12 12.4 1.0 1.7 1 0 0 1 1 1 0 Tenascin EGF domain bZIP_1 PF00170.21 CDJ96805.1 - 2.4 8.3 6.6 6.8 6.9 6.6 1.7 1 0 0 1 1 1 0 bZIP transcription factor TRAPPC9-Trs120 PF08626.11 CDJ96806.1 - 6.6e-21 73.5 0.0 7.6e-09 33.5 0.0 4.1 3 1 1 4 4 4 4 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit RRM_1 PF00076.22 CDJ96807.1 - 1.3e-16 60.2 0.0 1.8e-08 34.1 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 CDJ96807.1 - 0.032 14.4 0.4 27 5.0 0.0 3.4 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 CDJ96807.1 - 0.051 13.6 0.0 0.36 10.9 0.0 2.3 3 0 0 3 3 3 0 RNA binding motif Ion_trans_2 PF07885.16 CDJ96808.1 - 1.2e-17 63.6 16.7 3.1e-15 55.9 11.6 2.7 2 1 1 3 3 3 2 Ion channel HCV_NS4a PF01006.20 CDJ96808.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a DUF5379 PF17350.2 CDJ96808.1 - 0.54 10.6 6.7 0.36 11.1 0.2 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5379) Ion_trans PF00520.31 CDJ96808.1 - 0.6 9.3 7.7 1.3 8.2 7.8 1.5 1 1 0 1 1 1 0 Ion transport protein WW PF00397.26 CDJ96809.1 - 7.3e-09 35.6 1.7 1.5e-08 34.6 1.7 1.6 1 0 0 1 1 1 1 WW domain UAA PF08449.11 CDJ96810.1 - 5.9e-58 196.5 16.5 6.9e-58 196.2 16.5 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CDJ96810.1 - 1.8e-15 57.3 18.0 1.6e-08 34.8 5.9 2.7 2 1 1 3 3 3 2 EamA-like transporter family TPT PF03151.16 CDJ96810.1 - 4.9e-05 22.8 10.8 0.00015 21.2 10.8 1.8 1 1 0 1 1 1 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 CDJ96810.1 - 0.0012 18.1 0.7 0.25 10.5 0.1 2.3 2 1 0 2 2 2 2 Nucleotide-sugar transporter Dev_Cell_Death PF10539.9 CDJ96810.1 - 0.023 14.6 0.1 0.08 12.8 0.0 1.9 1 1 1 2 2 2 0 Development and cell death domain TctA PF01970.16 CDJ96810.1 - 0.069 11.9 6.7 0.099 11.3 6.0 1.7 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctA family DUF5367 PF17329.2 CDJ96810.1 - 0.13 12.4 3.9 5.1 7.3 0.8 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5367) CDP-OH_P_transf PF01066.21 CDJ96810.1 - 0.88 10.4 0.0 0.88 10.4 0.0 3.4 2 1 0 2 2 2 0 CDP-alcohol phosphatidyltransferase DUF2663 PF10864.8 CDJ96810.1 - 2 8.8 5.6 1.6 9.1 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2663) DUF3671 PF12420.8 CDJ96810.1 - 3.3 7.8 11.9 0.18 11.9 2.8 2.8 2 1 1 3 3 3 0 Protein of unknown function DUF2079 PF09852.9 CDJ96810.1 - 3.4 6.4 11.0 1 8.1 0.3 2.7 2 1 1 3 3 3 0 Predicted membrane protein (DUF2079) RIBIOP_C PF04950.12 CDJ96811.1 - 0.052 13.0 4.8 0.075 12.4 4.8 1.2 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal DNA_methylase PF00145.17 CDJ96811.1 - 0.35 10.2 3.3 0.47 9.8 3.3 1.1 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase HIG_1_N PF04588.13 CDJ96813.1 - 2.8e-14 53.1 3.6 4.2e-13 49.3 0.9 2.4 2 0 0 2 2 2 2 Hypoxia induced protein conserved region DUF1075 PF06388.11 CDJ96813.1 - 2e-08 34.3 0.1 4.6e-08 33.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1075) Presenilin PF01080.17 CDJ96814.1 - 0.07 11.9 14.4 0.079 11.7 14.4 1.0 1 0 0 1 1 1 0 Presenilin LicD PF04991.13 CDJ96814.1 - 0.16 12.0 15.9 0.19 11.9 15.9 1.1 1 0 0 1 1 1 0 LicD family CDC45 PF02724.14 CDJ96814.1 - 0.21 9.9 15.6 0.21 9.8 15.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Paramyxo_ncap PF00973.19 CDJ96814.1 - 0.24 10.3 12.1 0.28 10.1 12.1 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SLC12 PF03522.15 CDJ96814.1 - 0.32 10.0 17.7 0.36 9.8 17.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 AAA_11 PF13086.6 CDJ96814.1 - 0.34 10.7 15.7 0.36 10.6 15.7 1.0 1 0 0 1 1 1 0 AAA domain DUF3807 PF12720.7 CDJ96814.1 - 0.35 11.1 23.7 0.45 10.8 23.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) RR_TM4-6 PF06459.12 CDJ96814.1 - 0.38 10.5 19.9 0.42 10.4 19.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF5427 PF10310.9 CDJ96814.1 - 0.41 9.5 16.4 0.45 9.4 16.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Connexin PF00029.19 CDJ96814.1 - 0.52 10.0 13.6 0.59 9.9 13.6 1.2 1 0 0 1 1 1 0 Connexin SRP-alpha_N PF04086.13 CDJ96814.1 - 0.53 10.2 24.4 0.57 10.0 24.4 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CSG2 PF16965.5 CDJ96814.1 - 0.58 9.1 6.8 0.63 8.9 6.8 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator V_ATPase_I PF01496.19 CDJ96814.1 - 0.59 8.0 12.9 0.65 7.8 12.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CPSF100_C PF13299.6 CDJ96814.1 - 0.61 10.2 13.7 0.76 9.9 13.7 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2052 PF09747.9 CDJ96814.1 - 0.69 10.0 13.1 0.84 9.7 13.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF2828 PF11443.8 CDJ96814.1 - 0.7 7.9 18.6 0.78 7.8 18.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) GAGA_bind PF06217.12 CDJ96814.1 - 0.74 10.0 19.3 0.78 10.0 19.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF913 PF06025.12 CDJ96814.1 - 0.84 8.5 8.8 0.89 8.5 8.8 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Vfa1 PF08432.10 CDJ96814.1 - 0.87 9.9 27.0 1.1 9.5 27.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mpp10 PF04006.12 CDJ96814.1 - 0.93 7.9 25.6 1 7.7 25.6 1.1 1 0 0 1 1 1 0 Mpp10 protein EOS1 PF12326.8 CDJ96814.1 - 0.97 9.3 9.0 1.2 9.1 9.0 1.2 1 0 0 1 1 1 0 N-glycosylation protein DUF853 PF05872.12 CDJ96814.1 - 1.1 7.8 7.5 1.2 7.6 7.5 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Endostatin PF06482.11 CDJ96814.1 - 1.1 8.6 10.4 1.3 8.5 10.4 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin PPL5 PF18168.1 CDJ96814.1 - 1.4 8.1 15.2 1.9 7.7 15.2 1.3 1 0 0 1 1 1 0 Prim-pol family 5 ALMT PF11744.8 CDJ96814.1 - 1.4 7.6 13.3 1.5 7.5 13.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4604 PF15377.6 CDJ96814.1 - 1.7 9.1 31.4 2.1 8.8 31.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DDHD PF02862.17 CDJ96814.1 - 1.7 8.7 12.8 2 8.5 12.8 1.1 1 0 0 1 1 1 0 DDHD domain RP-C_C PF11800.8 CDJ96814.1 - 2.2 8.3 11.9 2.4 8.2 11.9 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Neur_chan_memb PF02932.16 CDJ96814.1 - 2.4 8.1 11.7 2.7 8.0 11.7 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 CDJ96814.1 - 2.5 7.2 12.4 2.9 7.0 12.4 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Tim54 PF11711.8 CDJ96814.1 - 2.5 6.8 18.1 2.8 6.6 18.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DAG_kinase_N PF14513.6 CDJ96814.1 - 2.9 8.1 14.9 3.7 7.7 14.9 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus DUF3405 PF11885.8 CDJ96814.1 - 3.9 6.0 12.7 4.2 5.8 12.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) GNAT_acetyltr_2 PF13718.6 CDJ96814.1 - 4.7 6.5 10.2 5.1 6.4 10.2 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 SspB PF04386.13 CDJ96814.1 - 4.9 7.0 11.9 6.6 6.6 11.9 1.3 1 0 0 1 1 1 0 Stringent starvation protein B Otopetrin PF03189.13 CDJ96814.1 - 7.1 5.3 10.3 7.1 5.3 10.3 1.1 1 0 0 1 1 1 0 Otopetrin Ctr PF04145.15 CDJ96814.1 - 7.1 7.2 7.7 8.7 6.9 7.7 1.2 1 0 0 1 1 1 0 Ctr copper transporter family FemAB PF02388.16 CDJ96814.1 - 8.5 5.1 17.7 10 4.8 17.7 1.1 1 0 0 1 1 1 0 FemAB family Pannexin_like PF12534.8 CDJ96814.1 - 9 5.3 11.2 10 5.1 11.2 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 AAA_12 PF13087.6 CDJ96815.1 - 7.5e-33 113.8 0.0 1.2e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ96815.1 - 4.6e-09 36.4 0.0 1.4e-08 34.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ96815.1 - 9.6e-08 32.0 0.1 0.0021 17.8 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CDJ96815.1 - 9.7e-06 26.0 0.2 0.00024 21.5 0.1 2.7 2 1 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 CDJ96815.1 - 0.0028 17.6 0.1 0.094 12.6 0.1 2.3 2 0 0 2 2 2 1 Helicase UvrD-helicase PF00580.21 CDJ96815.1 - 0.0032 17.1 2.4 0.12 11.9 0.7 2.9 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 CDJ96815.1 - 0.0078 16.0 0.1 0.041 13.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Viral_helicase1 PF01443.18 CDJ96815.1 - 0.0083 15.9 0.0 0.099 12.4 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 CDJ96815.1 - 0.026 14.5 0.5 0.098 12.7 0.1 2.2 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit RhoGEF PF00621.20 CDJ96817.1 - 1.9e-33 116.2 0.0 2.6e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 CDJ96817.1 - 3.7e-06 27.4 0.0 8.9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 PH domain Chordopox_A30L PF06015.12 CDJ96817.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus A30L protein Ion_trans PF00520.31 CDJ96819.1 - 3e-246 812.6 80.8 4e-66 222.7 20.1 4.1 4 0 0 4 4 4 4 Ion transport protein Ca_chan_IQ PF08763.11 CDJ96819.1 - 1.1e-30 105.7 0.1 2.3e-30 104.6 0.1 1.6 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain GPHH PF16905.5 CDJ96819.1 - 4.5e-30 103.2 0.1 9e-30 102.2 0.1 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 CDJ96819.1 - 6.2e-07 28.4 29.2 3.6e-06 25.9 9.1 9.3 7 3 2 10 10 10 6 Polycystin cation channel FAM176 PF14851.6 CDJ96819.1 - 0.039 13.6 4.9 4.4 7.0 0.0 2.8 2 0 0 2 2 2 0 FAM176 family RPN2_C PF18004.1 CDJ96819.1 - 3.6 7.5 6.9 80 3.1 6.5 2.4 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain GBP_C PF02841.14 CDJ96819.1 - 9.4 5.5 12.8 16 4.7 12.8 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Ion_trans PF00520.31 CDJ96820.1 - 4.7e-99 330.6 31.6 1.9e-59 200.8 8.9 3.0 2 1 1 3 3 3 3 Ion transport protein FAM176 PF14851.6 CDJ96820.1 - 0.0024 17.6 4.4 1.2 8.8 0.0 2.6 2 0 0 2 2 2 2 FAM176 family Bac_export_2 PF01312.19 CDJ96820.1 - 0.084 12.1 1.7 0.82 8.8 0.3 2.6 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family RPN2_C PF18004.1 CDJ96820.1 - 0.13 12.1 5.1 8.4 6.3 5.0 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain PKD_channel PF08016.12 CDJ96820.1 - 1.8 7.2 29.7 1.6 7.3 0.0 5.1 3 2 2 5 5 5 0 Polycystin cation channel Conotoxin PF02950.17 CDJ96820.1 - 1.8 9.7 4.3 67 4.6 1.4 3.1 2 0 0 2 2 2 0 Conotoxin RNA_pol_3_Rpc31 PF11705.8 CDJ96820.1 - 5.9 7.1 20.4 0.34 11.1 0.2 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Ca_chan_IQ PF08763.11 CDJ96821.1 - 1.5e-31 108.5 0.1 2.4e-31 107.8 0.1 1.4 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain GPHH PF16905.5 CDJ96821.1 - 5.8e-31 106.0 0.1 1.1e-30 105.1 0.1 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Ion_trans PF00520.31 CDJ96821.1 - 0.061 12.5 0.1 0.086 12.1 0.1 1.2 1 0 0 1 1 1 0 Ion transport protein Pep_deformylase PF01327.21 CDJ96821.1 - 0.12 11.9 0.1 0.59 9.7 0.0 2.0 2 0 0 2 2 2 0 Polypeptide deformylase Myosin_head PF00063.21 CDJ96822.1 - 2.9e-297 987.5 0.3 2.9e-297 987.5 0.3 3.4 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CDJ96822.1 - 3.1e-275 916.1 302.8 4e-275 915.7 302.8 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 CDJ96822.1 - 4.1e-15 55.3 3.2 8.6e-15 54.3 3.2 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Rimk_N PF18030.1 CDJ96822.1 - 0.0041 17.5 0.5 7.6 7.0 0.0 3.5 2 0 0 2 2 2 2 RimK PreATP-grasp domain IQ PF00612.27 CDJ96822.1 - 0.0046 16.6 0.4 0.024 14.4 0.4 2.4 1 0 0 1 1 1 1 IQ calmodulin-binding motif CbeA_antitoxin PF06154.11 CDJ96822.1 - 0.062 13.9 0.7 0.6 10.7 0.3 3.0 1 1 1 2 2 2 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A AAA_22 PF13401.6 CDJ96822.1 - 0.094 13.0 0.0 0.094 13.0 0.0 5.7 4 3 1 6 6 6 0 AAA domain TUDOR PF00567.24 CDJ96822.1 - 0.7 9.9 0.0 0.7 9.9 0.0 4.4 4 0 0 4 4 4 0 Tudor domain POTRA_3 PF17287.2 CDJ96822.1 - 1.1 8.8 4.6 13 5.4 0.1 4.0 3 0 0 3 3 3 0 POTRA domain DUF1647 PF07801.11 CDJ96823.1 - 0.00038 20.2 0.0 0.00083 19.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) Pribosyl_synth PF14572.6 CDJ96824.1 - 1.2e-77 260.1 0.0 1.4e-77 259.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CDJ96824.1 - 1.1e-05 25.0 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Arr-ms PF12120.8 CDJ96824.1 - 0.16 12.1 0.0 4.8 7.4 0.0 2.4 3 0 0 3 3 3 0 Rifampin ADP-ribosyl transferase Sulfate_transp PF00916.20 CDJ96825.1 - 3.6e-104 348.6 24.0 4.8e-104 348.1 24.0 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CDJ96825.1 - 1.7e-40 137.3 0.2 4.7e-19 68.1 0.0 2.6 3 0 0 3 3 3 2 STAS domain STAS_2 PF13466.6 CDJ96825.1 - 4.4e-07 30.1 0.0 0.021 15.1 0.0 2.5 2 0 0 2 2 2 2 STAS domain Ytca PF17090.5 CDJ96825.1 - 0.15 12.6 7.5 3.4 8.2 0.3 3.5 2 1 0 2 2 2 0 Uncharacterised protein family VHS PF00790.19 CDJ96826.1 - 7.1e-31 106.9 2.1 3.1e-29 101.6 0.0 3.4 4 0 0 4 4 4 1 VHS domain GGA_N-GAT PF18308.1 CDJ96826.1 - 1.2e-18 66.4 3.5 2.8e-18 65.3 3.5 1.7 1 0 0 1 1 1 1 GGA N-GAT domain GAT PF03127.14 CDJ96826.1 - 1.4e-11 44.5 7.0 7.5e-09 35.8 0.5 3.2 2 1 1 3 3 3 2 GAT domain DUF2624 PF11116.8 CDJ96826.1 - 0.0073 17.2 0.6 0.038 14.9 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2624) ABATE PF07336.11 CDJ96826.1 - 0.015 15.9 0.3 0.035 14.8 0.3 1.6 1 0 0 1 1 1 0 Putative stress-induced transcription regulator Ras PF00071.22 CDJ96827.1 - 2e-27 95.7 0.0 3.2e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ96827.1 - 6.5e-10 39.3 0.0 1.8e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CDJ96827.1 - 7.6e-07 28.9 0.0 1.8e-05 24.4 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 CDJ96827.1 - 0.0002 20.8 0.0 0.00032 20.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1_Xtn PF16897.5 CDJ96827.1 - 0.017 15.1 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 CDJ96827.1 - 0.021 14.9 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Spore_IV_A PF09547.10 CDJ96827.1 - 0.032 13.2 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) AAA_16 PF13191.6 CDJ96827.1 - 0.13 12.6 0.3 0.29 11.5 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain PFK PF00365.20 CDJ96830.1 - 1.5e-200 664.3 2.5 3.6e-109 364.5 0.3 2.1 2 0 0 2 2 2 2 Phosphofructokinase Thioredoxin PF00085.20 CDJ96831.1 - 2.2e-66 220.3 1.1 7.6e-33 112.6 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 CDJ96831.1 - 7.8e-44 149.8 12.3 4.3e-37 127.8 6.6 4.0 4 0 0 4 4 4 3 Thioredoxin-like domain OST3_OST6 PF04756.13 CDJ96831.1 - 2.5e-12 46.8 0.4 0.00018 21.0 0.0 3.4 3 0 0 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CDJ96831.1 - 3.1e-12 46.9 0.7 3.1e-05 24.4 0.0 3.8 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CDJ96831.1 - 2.4e-09 37.4 0.8 0.0063 16.8 0.0 4.1 3 1 1 4 4 4 3 Thioredoxin-like Thioredoxin_7 PF13899.6 CDJ96831.1 - 4.6e-07 29.9 0.1 0.0027 17.9 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 CDJ96831.1 - 3.4e-05 23.8 4.3 0.18 11.7 0.0 3.8 4 1 1 5 5 5 2 AhpC/TSA family Redoxin PF08534.10 CDJ96831.1 - 0.00032 20.4 3.5 0.16 11.7 0.1 3.7 3 1 0 4 4 4 2 Redoxin Thioredoxin_4 PF13462.6 CDJ96831.1 - 0.002 18.3 0.8 0.28 11.3 0.0 3.4 3 1 1 4 4 4 1 Thioredoxin TraF PF13728.6 CDJ96831.1 - 0.0029 17.5 0.0 0.73 9.6 0.0 2.5 2 0 0 2 2 2 2 F plasmid transfer operon protein Glutaredoxin PF00462.24 CDJ96831.1 - 0.017 15.3 0.4 0.85 9.9 0.0 3.0 3 0 0 3 3 3 0 Glutaredoxin VHS PF00790.19 CDJ96832.1 - 3.9e-40 137.0 0.1 1.4e-39 135.2 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 CDJ96832.1 - 5.7e-21 74.6 1.6 1.9e-20 72.9 1.6 2.0 1 0 0 1 1 1 1 GAT domain DUF883 PF05957.13 CDJ96832.1 - 0.0045 17.6 0.2 12 6.6 0.0 3.7 3 1 0 3 3 3 2 Bacterial protein of unknown function (DUF883) ENTH PF01417.20 CDJ96832.1 - 0.08 13.0 0.0 0.27 11.3 0.0 2.0 1 0 0 1 1 1 0 ENTH domain Rho_GDI PF02115.17 CDJ96833.1 - 8.9e-62 208.3 0.3 1e-61 208.1 0.3 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor PBP-Tp47_a PF14889.6 CDJ96833.1 - 0.027 14.1 0.2 0.79 9.4 0.0 2.3 2 0 0 2 2 2 0 Penicillin-binding protein Tp47 domain a CopC PF04234.12 CDJ96833.1 - 0.064 14.3 0.2 0.11 13.5 0.2 1.7 1 1 0 1 1 1 0 CopC domain Shisa PF13908.6 CDJ96834.1 - 0.017 15.3 0.2 0.024 14.9 0.2 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator OSTMP1 PF09777.9 CDJ96834.1 - 0.033 13.6 0.2 0.045 13.1 0.2 1.1 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor DUF5389 PF17364.2 CDJ96834.1 - 0.11 12.6 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5389) Neuropep_like PF15161.6 CDJ96835.1 - 0.0019 17.8 0.0 2 8.1 0.0 3.1 1 1 3 4 4 4 3 Neuropeptide-like DUF1962 PF09227.10 CDJ96835.1 - 0.69 10.3 5.9 1.8e+02 2.6 0.2 5.5 1 1 2 3 3 3 0 Domain of unknown function (DUF1962) TMC PF07810.13 CDJ96836.1 - 3.9e-38 130.5 2.6 3.9e-38 130.5 2.6 2.7 3 0 0 3 3 3 1 TMC domain BSP_II PF05432.11 CDJ96836.1 - 4.7 6.8 11.4 0.11 12.2 3.9 1.8 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF5641 PF18701.1 CDJ96838.1 - 9.9e-17 60.9 0.2 1.5e-16 60.3 0.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5641) FANCF PF11107.8 CDJ96838.1 - 0.068 12.4 0.2 0.09 12.0 0.2 1.1 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) Aa_trans PF01490.18 CDJ96839.1 - 8.6e-49 166.3 33.9 1e-48 166.1 33.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CDJ96839.1 - 0.001 18.2 26.1 0.024 13.7 26.2 2.2 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family YebO PF13974.6 CDJ96839.1 - 0.28 11.3 6.6 13 6.0 5.5 3.0 2 0 0 2 2 2 0 YebO-like protein DUF913 PF06025.12 CDJ96839.1 - 0.46 9.4 6.6 0.7 8.8 6.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF1840 PF08895.11 CDJ96839.1 - 2.8 8.3 9.9 5 7.5 9.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Transposase_24 PF03004.14 CDJ96839.1 - 3.7 7.6 9.4 3.8 7.6 8.4 1.4 1 1 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) Glyco_hydro_20 PF00728.22 CDJ96840.1 - 4.6e-10 39.4 0.0 9.7e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain TRAPPC10 PF12584.8 CDJ96840.1 - 0.034 13.9 0.0 0.11 12.2 0.0 1.7 1 1 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 Cor1 PF04803.12 CDJ96840.1 - 0.2 11.9 1.9 0.5 10.6 1.9 1.7 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region Myosin_tail_1 PF01576.19 CDJ96841.1 - 9.9e-54 182.6 158.2 2.7e-53 181.1 158.2 1.6 1 1 0 1 1 1 1 Myosin tail Filament PF00038.21 CDJ96841.1 - 7.6e-08 32.3 143.3 0.0029 17.2 28.0 6.8 1 1 4 5 5 5 4 Intermediate filament protein Tropomyosin_1 PF12718.7 CDJ96841.1 - 0.0034 17.5 22.9 0.0034 17.5 22.9 9.3 1 1 7 8 8 7 3 Tropomyosin like TMF_DNA_bd PF12329.8 CDJ96841.1 - 0.011 15.7 4.5 0.011 15.7 4.5 13.7 3 2 11 15 15 15 0 TATA element modulatory factor 1 DNA binding GIT_CC PF16559.5 CDJ96841.1 - 0.012 15.5 0.4 0.012 15.5 0.4 11.7 6 3 8 14 14 14 0 GIT coiled-coil Rho guanine nucleotide exchange factor HALZ PF02183.18 CDJ96841.1 - 0.021 15.0 2.6 0.021 15.0 2.6 9.8 9 2 3 12 12 11 0 Homeobox associated leucine zipper HisKA_3 PF07730.13 CDJ96841.1 - 0.033 14.7 2.3 0.033 14.7 2.3 10.6 5 3 5 10 10 9 0 Histidine kinase DUF745 PF05335.13 CDJ96841.1 - 0.098 12.4 126.6 0.025 14.3 13.5 6.8 1 1 3 6 6 6 0 Protein of unknown function (DUF745) Spc7 PF08317.11 CDJ96841.1 - 0.12 11.2 146.0 1.4 7.7 30.7 6.2 1 1 5 6 6 6 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 CDJ96841.1 - 1.3 9.1 170.1 0.13 12.3 17.5 8.5 2 1 3 6 6 6 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 CDJ96841.1 - 1.4 8.9 151.8 0.11 12.5 25.2 8.2 1 1 7 8 8 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 CDJ96841.1 - 9.2 6.3 88.2 0.33 11.0 3.5 8.8 2 2 7 11 11 11 0 Protein of unknown function (DUF1664) C2 PF00168.30 CDJ96842.1 - 6e-07 29.7 0.0 2.2e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 C2 domain TFIID_20kDa PF03847.13 CDJ96843.1 - 0.12 12.9 0.5 0.25 11.9 0.5 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Sema PF01403.19 CDJ96844.1 - 6.1e-85 285.6 0.0 9.5e-85 285.0 0.0 1.3 1 0 0 1 1 1 1 Sema domain I-set PF07679.16 CDJ96844.1 - 0.015 15.4 0.0 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ96844.1 - 0.018 15.6 0.0 0.056 14.0 0.0 1.9 1 0 0 1 1 1 0 Immunoglobulin domain PSI PF01437.25 CDJ96844.1 - 1.2 9.7 15.0 0.056 14.0 8.5 2.3 2 0 0 2 2 2 0 Plexin repeat NICE-3 PF07406.11 CDJ96845.1 - 1.9e-30 106.2 0.7 2.5e-30 105.8 0.7 1.1 1 0 0 1 1 1 1 NICE-3 protein EGF_2 PF07974.13 CDJ96846.1 - 0.06 13.7 0.6 0.06 13.7 0.6 3.5 3 0 0 3 3 3 0 EGF-like domain GPI2 PF06432.11 CDJ96847.1 - 6e-50 170.3 22.8 6.7e-50 170.1 22.8 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Lipase_2 PF01674.18 CDJ96848.1 - 5.4e-68 228.8 0.0 5.9e-68 228.7 0.0 1.0 1 0 0 1 1 1 1 Lipase (class 2) Palm_thioest PF02089.15 CDJ96848.1 - 0.056 13.3 0.1 0.66 9.8 0.0 1.9 1 1 1 2 2 2 0 Palmitoyl protein thioesterase LCAT PF02450.15 CDJ96848.1 - 0.069 12.3 0.0 0.078 12.1 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase ET PF01684.16 CDJ96849.1 - 3.8 7.9 20.0 4 7.9 9.4 2.6 2 0 0 2 2 2 0 ET module HSP20 PF00011.21 CDJ96850.1 - 4.9e-22 78.0 0.3 7e-22 77.5 0.3 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ96850.1 - 0.00074 19.0 0.0 0.0015 18.0 0.0 1.6 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CDC73_N PF16050.5 CDJ96852.1 - 1.4e-47 162.5 2.7 1.4e-47 162.5 2.7 1.6 2 0 0 2 2 2 1 Paf1 complex subunit CDC73 N-terminal CDC73_C PF05179.14 CDJ96852.1 - 1.2e-10 41.3 0.5 3e-10 40.0 0.5 1.7 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal Met_10 PF02475.16 CDJ96852.1 - 0.096 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein HnRNP_M PF11532.8 CDJ96852.1 - 0.38 11.0 3.2 1 9.7 3.2 1.7 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein M LSDAT_euk PF18139.1 CDJ96853.1 - 2.2e-98 328.9 0.0 3e-98 328.5 0.0 1.2 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 CDJ96853.1 - 3.2e-17 62.4 0.0 5.9e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 CDJ96853.1 - 6.7e-16 58.3 15.3 1e-15 57.7 15.3 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 CDJ96853.1 - 0.0033 16.2 3.0 0.0058 15.4 3.0 1.4 1 0 0 1 1 1 1 Polycystin cation channel DUF917 PF06032.12 CDJ96853.1 - 0.21 10.4 0.0 0.36 9.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF917) DUF1759 PF03564.15 CDJ96854.1 - 1.8e-27 96.1 3.9 3.3e-27 95.2 3.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Retrotran_gag_2 PF14223.6 CDJ96854.1 - 0.0011 18.6 1.2 0.0024 17.5 1.2 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Ly49 PF08391.10 CDJ96854.1 - 0.054 13.9 2.2 0.097 13.0 2.2 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Dioxygenase_N PF04444.14 CDJ96854.1 - 0.071 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Catechol dioxygenase N terminus FlxA PF14282.6 CDJ96854.1 - 1.9 8.5 7.9 6.1 6.9 7.9 1.8 1 0 0 1 1 1 0 FlxA-like protein Beach PF02138.18 CDJ96855.1 - 7.7e-120 399.4 0.1 1.1e-119 399.0 0.1 1.2 1 0 0 1 1 1 1 Beige/BEACH domain FYVE PF01363.21 CDJ96855.1 - 9e-17 61.0 17.5 2.3e-16 59.7 17.5 1.7 1 0 0 1 1 1 1 FYVE zinc finger WD40 PF00400.32 CDJ96855.1 - 1.2e-06 29.1 19.6 0.001 19.8 0.6 5.8 4 1 0 4 4 4 3 WD domain, G-beta repeat zinc_ribbon_4 PF13717.6 CDJ96855.1 - 3.7 7.5 9.5 17 5.4 9.5 2.2 1 1 0 1 1 1 0 zinc-ribbon domain PknG_rubred PF16919.5 CDJ96855.1 - 6.2 7.0 7.1 0.56 10.4 1.0 2.1 1 1 1 2 2 2 0 Protein kinase G rubredoxin domain Vg_Tdu PF07545.14 CDJ96857.1 - 0.035 13.9 4.2 2.6 7.9 1.2 2.5 2 0 0 2 2 2 0 Vestigial/Tondu family ShK PF01549.24 CDJ96858.1 - 6.6e-05 23.4 3.1 6.6e-05 23.4 3.1 1.7 2 0 0 2 2 2 1 ShK domain-like Ycf70 PF17382.2 CDJ96858.1 - 0.14 12.6 0.2 0.17 12.3 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized Ycf70-like GTP-bdg_N PF13167.6 CDJ96859.1 - 0.0041 17.8 1.8 5.9 7.6 0.0 3.6 2 1 2 4 4 4 3 GTP-binding GTPase N-terminal Nudix_hydro PF18290.1 CDJ96860.1 - 7.5e-28 96.3 0.1 3.7e-27 94.1 0.2 1.9 2 0 0 2 2 2 1 Nudix hydrolase domain NUDIX PF00293.28 CDJ96860.1 - 8.4e-18 64.7 0.1 1.2e-17 64.2 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain zf-Di19 PF05605.12 CDJ96861.1 - 0.00084 19.6 11.0 0.25 11.7 0.0 3.0 3 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 CDJ96861.1 - 0.012 16.0 15.3 0.055 13.9 1.0 4.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type Spore_II_R PF09551.10 CDJ96861.1 - 0.024 15.1 0.2 0.084 13.3 0.1 2.0 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) Exonuc_VII_S PF02609.16 CDJ96861.1 - 0.13 12.3 0.2 0.13 12.3 0.2 3.1 4 0 0 4 4 4 0 Exonuclease VII small subunit zf-C2H2_9 PF16293.5 CDJ96861.1 - 0.17 11.7 1.5 0.53 10.2 1.5 1.9 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) zf-C2H2_4 PF13894.6 CDJ96861.1 - 0.25 12.3 26.2 0.43 11.5 0.6 5.8 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ96861.1 - 0.74 10.2 8.8 7 7.1 0.2 4.6 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Prok-RING_2 PF14445.6 CDJ96861.1 - 5.1 7.3 0.0 5.1 7.3 0.0 3.8 3 1 1 4 4 4 0 Prokaryotic RING finger family 2 zf-BED PF02892.15 CDJ96861.1 - 8.3 6.5 9.8 32 4.6 0.3 3.7 2 1 1 3 3 3 0 BED zinc finger FMO-like PF00743.19 CDJ96862.1 - 9.9e-170 565.4 0.0 1.2e-169 565.2 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CDJ96862.1 - 1.2e-20 74.0 0.0 1.6e-15 57.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CDJ96862.1 - 1.1e-15 57.6 0.0 1.2e-14 54.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CDJ96862.1 - 1.6e-13 50.5 0.2 7.2e-11 41.8 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 CDJ96862.1 - 1.7e-07 31.7 0.9 7.7e-05 23.2 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CDJ96862.1 - 3.8e-06 27.0 0.1 0.00067 19.7 0.0 3.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CDJ96862.1 - 5.9e-06 26.4 0.3 0.00011 22.4 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CDJ96862.1 - 0.00027 20.6 0.1 2.3 7.7 0.0 3.3 3 1 0 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 CDJ96862.1 - 0.0051 16.1 0.1 1.6 7.9 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_7 PF13241.6 CDJ96862.1 - 0.03 14.7 0.0 2.9 8.4 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Amino_oxidase PF01593.24 CDJ96862.1 - 0.054 12.8 0.0 0.24 10.6 0.0 1.9 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 CDJ96862.1 - 0.057 12.1 0.1 2.2 6.9 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.21 CDJ96862.1 - 0.065 12.5 0.1 0.57 9.4 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 CDJ96862.1 - 0.17 11.4 0.0 19 4.8 0.0 3.0 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 CDJ96862.1 - 0.41 10.3 1.9 0.5 10.0 0.1 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 CDJ96862.1 - 0.44 9.7 3.9 1.4 8.0 0.1 2.7 2 1 1 3 3 3 0 FAD binding domain ATP-synt_ab PF00006.25 CDJ96863.1 - 3.3e-68 229.5 0.0 4.6e-68 229.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CDJ96863.1 - 3.5e-14 53.1 0.1 6.4e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 CDJ96863.1 - 0.014 15.5 0.1 0.027 14.6 0.1 1.5 1 0 0 1 1 1 0 HAS barrel domain DUF3762 PF12591.8 CDJ96863.1 - 0.17 12.1 0.0 0.37 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) Adenylate_cycl PF01295.18 CDJ96863.1 - 0.25 9.9 0.0 0.34 9.5 0.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase, class-I Atg8 PF02991.16 CDJ96865.1 - 1.4e-47 160.2 0.2 2.8e-47 159.2 0.2 1.5 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like zf-C3HC4_2 PF13923.6 CDJ96865.1 - 8.7e-10 38.3 10.2 1.5e-09 37.5 10.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ96865.1 - 9.5e-09 35.0 9.5 1.7e-08 34.2 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ96865.1 - 3.4e-08 33.7 9.0 6.6e-08 32.8 9.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDJ96865.1 - 9.3e-08 31.8 6.9 1.7e-07 30.9 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDJ96865.1 - 6.5e-07 29.5 5.3 1.4e-06 28.5 5.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CDJ96865.1 - 3.9e-05 23.6 6.2 8.8e-05 22.4 6.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger APG12 PF04110.13 CDJ96865.1 - 7.3e-05 23.1 0.0 0.00024 21.4 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-like autophagy protein Apg12 zf-RING_5 PF14634.6 CDJ96865.1 - 0.00026 20.9 8.0 0.00046 20.1 8.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDJ96865.1 - 0.00031 20.5 7.7 0.0006 19.6 7.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CDJ96865.1 - 0.0013 18.7 1.3 0.0032 17.5 1.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 CDJ96865.1 - 0.0015 18.6 8.1 0.0029 17.7 8.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 CDJ96865.1 - 0.025 14.4 1.6 0.047 13.5 1.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 CDJ96865.1 - 0.24 11.3 2.3 0.61 10.0 2.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 CDJ96865.1 - 0.26 11.5 6.0 0.52 10.5 6.0 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 CDJ96865.1 - 2.2 8.1 6.9 5 7.0 6.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Metallophos PF00149.28 CDJ96866.1 - 1.9e-34 120.0 0.2 3.1e-34 119.3 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDJ96866.1 - 2.2e-11 44.0 0.3 9.7e-11 41.9 0.1 2.3 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Thiamine_BP PF01910.17 CDJ96866.1 - 0.081 12.9 0.3 0.53 10.2 0.4 2.2 2 0 0 2 2 2 0 Thiamine-binding protein Herpes_DNAp_acc PF04929.12 CDJ96866.1 - 0.87 8.5 9.4 1.2 8.0 9.4 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SKA1 PF07160.12 CDJ96866.1 - 3.3 7.5 10.4 9.2 6.0 10.4 1.7 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Peptidase_A17 PF05380.13 CDJ96867.1 - 6.9e-39 133.4 0.1 1.5e-38 132.4 0.1 1.6 1 0 0 1 1 1 1 Pao retrotransposon peptidase TRIQK PF15168.6 CDJ96869.1 - 0.64 9.9 0.1 0.64 9.9 0.1 3.1 3 1 0 3 3 3 0 Triple QxxK/R motif-containing protein family DUF2663 PF10864.8 CDJ96869.1 - 0.97 9.8 6.8 1.6 9.1 1.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) FtsH_ext PF06480.15 CDJ96869.1 - 8 6.9 5.8 84 3.6 5.8 2.7 1 1 0 1 1 1 0 FtsH Extracellular Collagen PF01391.18 CDJ96872.1 - 2.1e-21 75.4 86.9 1.8e-08 34.0 30.1 4.0 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Tetraspanin PF00335.20 CDJ96873.1 - 7e-07 29.2 0.1 9.6e-07 28.7 0.1 1.1 1 0 0 1 1 1 1 Tetraspanin family COesterase PF00135.28 CDJ96874.1 - 0.00054 18.9 2.1 0.00066 18.7 2.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family RVT_1 PF00078.27 CDJ96875.1 - 6.1e-26 91.3 0.0 8e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rpn9_C PF18261.1 CDJ96877.1 - 0.043 13.4 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 Rpn9 C-terminal helix Glycos_transf_2 PF00535.26 CDJ96879.1 - 4.3e-17 62.4 0.0 8.5e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 CDJ96879.1 - 3.9e-12 46.2 0.0 7.4e-11 42.0 0.0 2.3 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 CDJ96879.1 - 4.6e-09 36.5 0.0 6.2e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 CDJ96879.1 - 8.1e-05 23.1 0.0 0.0025 18.3 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 zf-DNL PF05180.12 CDJ96880.1 - 1.1e-27 95.7 0.5 1.5e-27 95.3 0.5 1.2 1 0 0 1 1 1 1 DNL zinc finger PDH PF02153.17 CDJ96880.1 - 0.032 13.2 0.0 0.042 12.9 0.0 1.1 1 0 0 1 1 1 0 Prephenate dehydrogenase Stc1 PF12898.7 CDJ96880.1 - 0.093 13.3 0.6 0.18 12.4 0.6 1.5 1 1 0 1 1 1 0 Stc1 domain zf-RING_7 PF02591.15 CDJ96880.1 - 0.15 12.3 2.5 0.34 11.1 2.5 1.6 1 1 0 1 1 1 0 C4-type zinc ribbon domain SHMT PF00464.19 CDJ96880.1 - 0.15 10.6 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Serine hydroxymethyltransferase Coq4 PF05019.13 CDJ96881.1 - 9.9e-78 260.5 0.1 1.1e-77 260.3 0.1 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 P16-Arc PF04699.14 CDJ96882.1 - 3.6e-43 147.6 0.0 4e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) PigN PF04987.14 CDJ96883.1 - 4e-66 223.8 45.4 1.1e-63 215.7 34.2 2.4 2 1 1 3 3 3 2 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 CDJ96883.1 - 4.5e-08 33.1 0.4 6.6e-05 22.7 0.3 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CDJ96883.1 - 0.0045 16.4 0.1 0.0071 15.7 0.1 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 CDJ96883.1 - 0.093 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Sulfatase PglZ PF08665.12 CDJ96883.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 PglZ domain Pkinase PF00069.25 CDJ96884.1 - 2.7e-59 200.7 0.1 1e-52 179.1 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ96884.1 - 1.9e-33 115.9 0.0 9e-33 113.6 0.0 1.8 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ96884.1 - 0.011 15.1 0.0 0.082 12.2 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 CDJ96884.1 - 0.034 12.9 0.0 0.047 12.5 0.0 1.4 1 1 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 CDJ96884.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Ribosomal_L7Ae PF01248.26 CDJ96885.1 - 4.8e-10 39.0 0.0 8.9e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Nexin_C PF08628.12 CDJ96885.1 - 0.057 14.0 1.0 0.24 12.0 0.2 2.2 2 0 0 2 2 2 0 Sorting nexin C terminal Abhydrolase_2 PF02230.16 CDJ96886.1 - 2.8e-78 262.7 0.0 3.1e-78 262.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 CDJ96886.1 - 4.2e-11 42.6 0.4 2.1e-05 23.9 0.2 2.7 2 1 1 3 3 3 2 Serine aminopeptidase, S33 DLH PF01738.18 CDJ96886.1 - 7.8e-09 35.4 0.0 1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 CDJ96886.1 - 1.1e-06 28.5 1.2 7.3e-05 22.5 0.2 2.6 2 1 1 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ96886.1 - 2.7e-06 28.2 0.2 3.2e-06 27.9 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CDJ96886.1 - 0.0019 18.1 0.3 0.23 11.3 0.1 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 CDJ96886.1 - 0.0046 16.6 0.0 0.0073 16.0 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 CDJ96886.1 - 0.0053 16.3 0.4 0.085 12.3 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2974 PF11187.8 CDJ96886.1 - 0.016 14.8 0.1 0.023 14.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 CDJ96886.1 - 0.022 14.7 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2920 PF11144.8 CDJ96886.1 - 0.039 13.1 0.2 2.7 7.1 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) FSH1 PF03959.13 CDJ96886.1 - 0.041 13.6 0.0 0.18 11.5 0.0 1.9 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Cutinase PF01083.22 CDJ96886.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Cutinase Branch PF02485.21 CDJ96887.1 - 4.3e-28 98.5 0.1 7.9e-28 97.6 0.1 1.5 1 1 0 1 1 1 1 Core-2/I-Branching enzyme zf-C3HC4_3 PF13920.6 CDJ96888.1 - 0.00017 21.4 11.7 0.00024 20.9 11.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ96888.1 - 0.0098 16.2 14.0 0.015 15.6 14.0 1.3 1 0 0 1 1 1 1 Ring finger domain SpecificRecomb PF10136.9 CDJ96888.1 - 0.044 12.1 0.0 0.055 11.8 0.0 1.0 1 0 0 1 1 1 0 Site-specific recombinase DUF2310 PF10071.9 CDJ96888.1 - 0.062 12.6 0.5 0.11 11.8 0.5 1.4 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) Alpha-2-MRAP_C PF06401.11 CDJ96888.1 - 0.11 12.5 0.2 0.13 12.2 0.2 1.1 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain zf-C3HC4 PF00097.25 CDJ96888.1 - 0.26 11.2 9.0 0.59 10.0 9.0 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDJ96888.1 - 2.1 8.3 10.0 9.5 6.2 10.1 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CDJ96888.1 - 6.6 6.8 13.7 11 6.1 13.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Zw10 PF06248.13 CDJ96889.1 - 8.8e-68 229.2 1.9 8.8e-68 229.2 1.9 1.4 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 PsbQ PF05757.11 CDJ96889.1 - 4.7 6.9 5.8 2.1 8.0 0.1 2.5 3 0 0 3 3 3 0 Oxygen evolving enhancer protein 3 (PsbQ) ABC_membrane PF00664.23 CDJ96890.1 - 4.3e-123 410.3 21.3 1.3e-67 228.3 6.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ96890.1 - 1.2e-72 242.8 0.0 2.9e-36 125.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CDJ96890.1 - 2.9e-18 66.1 0.9 5e-08 32.7 0.0 4.1 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDJ96890.1 - 9e-11 42.4 0.3 0.00054 20.4 0.0 3.1 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CDJ96890.1 - 5.2e-09 36.5 0.1 0.00092 19.5 0.0 3.3 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 CDJ96890.1 - 2e-08 33.8 0.3 0.00031 20.1 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin RsgA_GTPase PF03193.16 CDJ96890.1 - 3.1e-08 33.7 0.3 0.005 16.8 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_15 PF13175.6 CDJ96890.1 - 3.5e-08 33.6 0.0 0.0011 18.8 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 CDJ96890.1 - 8.7e-07 28.1 0.1 0.013 14.4 0.0 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 CDJ96890.1 - 1.1e-06 28.3 0.3 0.065 13.0 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA PF00004.29 CDJ96890.1 - 1.9e-06 28.3 0.0 0.069 13.6 0.0 3.5 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 CDJ96890.1 - 5.5e-06 25.8 0.0 0.082 12.1 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_5 PF07728.14 CDJ96890.1 - 7.3e-06 26.0 0.3 0.1 12.6 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CDJ96890.1 - 7.7e-06 25.5 0.1 0.096 12.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF815 PF05673.13 CDJ96890.1 - 9e-06 25.0 0.1 0.084 12.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) APS_kinase PF01583.20 CDJ96890.1 - 1.3e-05 25.2 0.0 0.0011 18.9 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase PRK PF00485.18 CDJ96890.1 - 2.9e-05 23.9 0.0 0.036 13.8 0.0 2.4 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 CDJ96890.1 - 0.00015 22.1 0.0 1.2 9.4 0.0 3.0 2 1 1 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 CDJ96890.1 - 0.00016 21.7 0.1 0.2 11.7 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 CDJ96890.1 - 0.00021 21.0 0.7 0.56 9.8 0.0 2.7 2 1 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.6 CDJ96890.1 - 0.00043 20.3 0.1 0.41 10.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 CDJ96890.1 - 0.00043 20.0 1.5 0.18 11.5 0.0 3.4 2 2 0 2 2 2 1 AAA domain Rad17 PF03215.15 CDJ96890.1 - 0.00046 20.2 0.2 1 9.3 0.1 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain RNA_helicase PF00910.22 CDJ96890.1 - 0.00051 20.4 0.2 3 8.3 0.0 3.3 3 1 0 3 3 2 2 RNA helicase AAA_24 PF13479.6 CDJ96890.1 - 0.00052 19.8 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 CDJ96890.1 - 0.00081 19.5 2.7 1.1 9.3 0.2 3.0 2 1 1 3 3 3 2 Helicase HerA, central domain AAA_21 PF13304.6 CDJ96890.1 - 0.0011 18.8 1.7 8.1 6.1 0.0 4.2 3 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CDJ96890.1 - 0.0016 19.0 0.0 1.2 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain tRNA_lig_kinase PF08303.11 CDJ96890.1 - 0.0018 18.4 0.1 1.2 9.2 0.0 2.7 2 0 0 2 2 2 1 tRNA ligase kinase domain AAA_25 PF13481.6 CDJ96890.1 - 0.0019 17.8 0.0 1.8 8.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 CDJ96890.1 - 0.0021 18.0 0.0 0.36 10.7 0.0 2.6 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 CDJ96890.1 - 0.0037 17.4 0.1 4 7.6 0.0 2.8 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 CDJ96890.1 - 0.0042 17.3 4.8 2.5 8.4 0.4 3.9 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 CDJ96890.1 - 0.0051 17.4 0.0 4.2 7.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain Ras PF00071.22 CDJ96890.1 - 0.0062 16.1 0.1 2.2 7.9 0.0 2.6 2 0 0 2 2 2 1 Ras family FeoB_N PF02421.18 CDJ96890.1 - 0.0065 16.0 0.2 3.1 7.3 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B IstB_IS21 PF01695.17 CDJ96890.1 - 0.0075 16.0 0.4 15 5.3 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein NB-ARC PF00931.22 CDJ96890.1 - 0.0076 15.5 0.3 2.6 7.2 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Roc PF08477.13 CDJ96890.1 - 0.014 15.6 1.1 3.3 7.9 0.0 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 CDJ96890.1 - 0.015 14.6 0.0 5.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Septin DUF2207 PF09972.9 CDJ96890.1 - 0.02 13.7 0.0 0.02 13.7 0.0 3.7 3 1 0 3 3 2 0 Predicted membrane protein (DUF2207) CbiA PF01656.23 CDJ96890.1 - 0.026 14.6 0.0 6.6 6.8 0.0 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain KAP_NTPase PF07693.14 CDJ96890.1 - 0.028 13.7 0.0 0.48 9.6 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain RepB-RCR_reg PF10723.9 CDJ96890.1 - 0.03 14.3 0.2 14 5.7 0.0 3.4 3 0 0 3 3 3 0 Replication regulatory protein RepB SRP54 PF00448.22 CDJ96890.1 - 0.037 13.7 0.1 5.9 6.5 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MeaB PF03308.16 CDJ96890.1 - 0.044 12.8 0.0 1.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 CDJ96890.1 - 0.045 13.7 0.2 4.5 7.1 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.23 CDJ96890.1 - 0.047 13.7 0.5 3.4 7.7 0.0 3.0 3 0 0 3 3 3 0 Dynamin family ABC_membrane_3 PF13748.6 CDJ96890.1 - 0.064 12.5 1.2 0.24 10.6 0.1 2.2 2 0 0 2 2 2 0 ABC transporter transmembrane region TniB PF05621.11 CDJ96890.1 - 0.081 12.3 0.0 17 4.8 0.0 3.0 3 0 0 3 3 3 0 Bacterial TniB protein AIG1 PF04548.16 CDJ96890.1 - 0.27 10.6 1.9 6.5 6.0 0.0 2.9 3 0 0 3 3 2 0 AIG1 family DUF2852 PF11014.8 CDJ96890.1 - 0.28 11.3 4.0 1.7 8.8 0.1 3.0 3 0 0 3 3 2 0 Protein of unknown function (DUF2852) NTPase_1 PF03266.15 CDJ96890.1 - 2.2 8.1 4.9 51 3.7 0.1 3.7 4 0 0 4 4 4 0 NTPase LapA_dom PF06305.11 CDJ96892.1 - 1.8 8.4 3.0 0.91 9.4 0.1 1.9 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain RVT_1 PF00078.27 CDJ96893.1 - 5.1e-10 39.2 0.0 9.6e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RL11D PF11088.8 CDJ96893.1 - 0.039 14.2 0.0 0.094 13.0 0.0 1.6 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 DUF1759 PF03564.15 CDJ96894.1 - 3.7e-22 78.9 0.4 5.2e-22 78.4 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) PI_PP_C PF18365.1 CDJ96894.1 - 0.022 14.7 0.1 0.038 14.0 0.1 1.5 1 0 0 1 1 1 0 Phosphoinositide phosphatase C-terminal domain Recep_L_domain PF01030.24 CDJ96895.1 - 4.2e-10 39.7 0.1 7.4e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 Receptor L domain DUF2561 PF10812.8 CDJ96895.1 - 0.0055 16.8 0.1 0.0074 16.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) LPG_synthase_TM PF03706.13 CDJ96895.1 - 0.0056 16.3 0.1 0.0072 15.9 0.1 1.1 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region SP_C-Propep PF08999.10 CDJ96895.1 - 0.012 15.4 0.8 0.02 14.7 0.8 1.3 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Amnionless PF14828.6 CDJ96895.1 - 0.014 14.3 0.2 0.017 14.0 0.2 1.1 1 0 0 1 1 1 0 Amnionless EVI2A PF05399.11 CDJ96895.1 - 0.022 14.4 0.1 0.029 13.9 0.1 1.3 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) EphA2_TM PF14575.6 CDJ96895.1 - 0.04 14.8 0.4 0.067 14.1 0.4 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 CDJ96895.1 - 0.069 13.1 0.2 0.1 12.5 0.2 1.5 1 0 0 1 1 1 0 TMEM154 protein family Sid-5 PF17204.3 CDJ96895.1 - 0.12 12.6 0.3 0.21 11.8 0.3 1.4 1 0 0 1 1 1 0 Sid-5 family Orf78 PF06024.12 CDJ96895.1 - 0.21 11.9 0.6 0.33 11.3 0.5 1.4 1 1 0 1 1 1 0 Orf78 (ac78) Baculo_11_kDa PF06143.11 CDJ96895.1 - 0.27 10.9 1.7 0.62 9.7 1.7 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family RVT_1 PF00078.27 CDJ96896.1 - 1.1e-37 129.8 0.0 2.1e-37 128.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Recep_L_domain PF01030.24 CDJ96897.1 - 4.8e-33 113.6 0.6 1.3e-08 34.9 0.0 4.7 4 1 0 4 4 4 4 Receptor L domain Recep_L_domain PF01030.24 CDJ96898.1 - 2.9e-32 111.1 4.6 3.2e-09 36.9 0.1 4.9 4 1 0 4 4 4 4 Receptor L domain Pkinase_Tyr PF07714.17 CDJ96899.1 - 8.4e-48 162.9 0.0 1e-47 162.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ96899.1 - 8.8e-23 81.0 0.0 1.2e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF148 PF02520.17 CDJ96901.1 - 6.2e-07 29.5 0.1 8e-07 29.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF148 Flagellin_N PF00669.20 CDJ96901.1 - 0.028 14.5 0.9 0.047 13.8 0.9 1.3 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region RR_TM4-6 PF06459.12 CDJ96902.1 - 0.003 17.4 0.7 0.0074 16.2 0.7 1.6 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 MH2 PF03166.14 CDJ96903.1 - 1.1e-40 139.8 0.0 1.9e-40 139.1 0.0 1.3 1 0 0 1 1 1 1 MH2 domain ATP-cone PF03477.16 CDJ96904.1 - 0.1 13.1 0.2 9.6 6.9 0.0 3.0 3 0 0 3 3 3 0 ATP cone domain TTR-52 PF01060.23 CDJ96905.1 - 3.3e-23 82.2 0.1 4.3e-23 81.8 0.1 1.2 1 0 0 1 1 1 1 Transthyretin-like family YAF2_RYBP PF17219.3 CDJ96905.1 - 0.017 14.7 0.2 0.039 13.6 0.2 1.6 1 0 0 1 1 1 0 Yaf2/RYBP C-terminal binding motif RVT_1 PF00078.27 CDJ96906.1 - 7.3e-14 51.8 0.0 9.4e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Homeodomain PF00046.29 CDJ96907.1 - 3.6e-23 81.2 2.3 1e-22 79.7 2.1 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CDJ96907.1 - 0.028 14.3 0.1 0.08 12.9 0.1 1.8 2 0 0 2 2 2 0 Homeobox KN domain HTH_28 PF13518.6 CDJ96907.1 - 0.074 13.2 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Cyclin_N PF00134.23 CDJ96908.1 - 3.1e-36 123.9 1.7 9.7e-35 119.1 0.1 2.7 2 1 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 CDJ96908.1 - 1.4e-23 83.2 1.0 4.5e-23 81.6 0.5 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF1757 PF08560.10 CDJ96909.1 - 3e-52 176.6 0.1 6.2e-52 175.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) SMC_N PF02463.19 CDJ96909.1 - 4.4e-48 163.6 59.9 1e-29 103.6 5.6 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CDJ96909.1 - 5.2e-18 65.5 0.2 2.7e-17 63.1 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 CDJ96909.1 - 1.4e-17 64.9 4.7 1.4e-17 64.9 4.7 7.9 3 2 2 5 5 5 1 AAA domain AAA_21 PF13304.6 CDJ96909.1 - 5e-17 62.7 4.4 1.4e-07 31.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CDJ96909.1 - 9.8e-11 42.0 9.0 9.8e-11 42.0 9.0 4.5 2 2 2 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 CDJ96909.1 - 7.7e-08 32.0 0.0 1.6e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 CDJ96909.1 - 0.062 13.5 0.0 0.19 12.0 0.0 1.9 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 CDJ96909.1 - 0.22 11.8 2.0 7.5 6.8 0.0 4.0 4 0 0 4 4 4 0 AAA domain Shisa PF13908.6 CDJ96910.1 - 0.044 14.0 0.6 0.044 14.0 0.6 1.9 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator SR-25 PF10500.9 CDJ96910.1 - 0.073 12.7 15.0 0.025 14.2 12.3 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Neur_chan_memb PF02932.16 CDJ96910.1 - 0.46 10.5 4.1 0.74 9.8 4.1 1.3 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GIY-YIG PF01541.24 CDJ96912.1 - 0.0011 19.3 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain Exo_endo_phos_2 PF14529.6 CDJ96913.1 - 2.4e-05 24.1 0.2 0.00017 21.4 0.2 2.0 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ96913.1 - 0.0028 17.2 0.0 0.0048 16.4 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Presenilin PF01080.17 CDJ96915.1 - 8.2 5.1 5.8 10 4.7 5.8 1.1 1 0 0 1 1 1 0 Presenilin SIR2 PF02146.17 CDJ96917.1 - 1.7e-47 161.6 0.0 2.8e-47 160.9 0.0 1.3 1 0 0 1 1 1 1 Sir2 family zf-4CXXC_R1 PF10497.9 CDJ96917.1 - 0.02 15.1 0.1 0.048 13.9 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 TPP_enzyme_M PF00205.22 CDJ96917.1 - 0.062 13.0 0.0 0.17 11.6 0.0 1.7 1 1 1 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Col_cuticle_N PF01484.17 CDJ96918.1 - 8.9e-12 44.9 3.5 1.2e-11 44.5 3.5 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain DUF3887 PF13026.6 CDJ96918.1 - 0.15 12.9 0.0 0.21 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) Pkinase PF00069.25 CDJ96919.1 - 9.3e-11 41.6 0.0 1.4e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ96919.1 - 0.0031 16.8 0.0 0.0056 16.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase CN_hydrolase PF00795.22 CDJ96920.1 - 3.2e-33 115.2 0.0 4.6e-17 62.2 0.0 2.8 1 1 1 2 2 2 2 Carbon-nitrogen hydrolase RT_RNaseH_2 PF17919.1 CDJ96922.1 - 2.8e-34 117.1 0.0 3e-33 113.8 0.0 2.8 4 1 1 5 5 5 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ96922.1 - 3.8e-30 104.3 0.0 1.9e-29 102.0 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ96922.1 - 8.5e-21 74.5 0.0 1.8e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ96922.1 - 4.8e-17 61.8 0.1 1.1e-16 60.6 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 CDJ96922.1 - 6e-09 36.4 0.0 1.4e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ96922.1 - 2.6e-08 34.4 0.0 6.6e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ96922.1 - 0.0021 18.4 0.0 0.0053 17.0 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 CDJ96922.1 - 0.0032 17.6 0.2 0.0098 16.1 0.2 1.9 1 0 0 1 1 1 1 H2C2 zinc finger gag_pre-integrs PF13976.6 CDJ96922.1 - 0.12 12.3 0.3 0.36 10.7 0.1 1.9 2 0 0 2 2 2 0 GAG-pre-integrase domain rve PF00665.26 CDJ96923.1 - 2.9e-24 85.6 0.0 1.2e-23 83.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 CDJ96923.1 - 1e-05 25.2 0.0 2.7e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.6 CDJ96923.1 - 1.6e-05 24.7 0.1 3.9e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HisKA PF00512.25 CDJ96923.1 - 0.16 12.0 0.2 0.48 10.5 0.2 1.7 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain Actin PF00022.19 CDJ96924.1 - 1.6e-141 471.6 0.1 4.7e-101 338.3 0.0 2.7 1 1 1 2 2 2 2 Actin GerD PF17898.1 CDJ96924.1 - 0.062 13.3 0.1 0.8 9.7 0.1 2.5 2 0 0 2 2 2 0 Spore germination GerD central core domain Methyltransf_29 PF03141.16 CDJ96924.1 - 0.17 10.4 0.0 0.25 9.9 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase AMP-binding PF00501.28 CDJ96927.1 - 2e-78 263.9 0.0 2.4e-78 263.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ96927.1 - 8.5e-15 55.5 1.0 2.2e-14 54.2 1.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Frankia_peptide PF14407.6 CDJ96927.1 - 0.14 12.2 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Amino_oxidase PF01593.24 CDJ96928.1 - 1.1e-70 239.2 0.0 1.4e-70 238.8 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ96928.1 - 2.9e-14 53.1 0.2 6.8e-14 51.9 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CDJ96928.1 - 2.5e-05 23.7 0.1 7.7e-05 22.1 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CDJ96928.1 - 3e-05 23.4 0.2 4.7e-05 22.8 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 CDJ96928.1 - 0.00012 21.3 0.3 0.00017 20.8 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 CDJ96928.1 - 0.0003 20.8 0.1 0.2 11.7 0.2 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 CDJ96928.1 - 0.00036 19.9 0.1 0.008 15.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ96928.1 - 0.0025 16.6 0.4 0.006 15.3 0.4 1.6 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 CDJ96928.1 - 0.0034 16.7 0.4 0.0059 15.9 0.4 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 CDJ96928.1 - 0.0038 17.8 0.4 0.013 16.0 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CDJ96928.1 - 0.0046 16.3 0.0 0.0069 15.7 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 CDJ96928.1 - 0.0087 15.7 1.5 0.045 13.3 2.5 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CDJ96928.1 - 0.016 14.6 0.2 0.025 13.9 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 CDJ96928.1 - 0.035 13.2 0.3 0.057 12.5 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A IcmF-related PF06761.12 CDJ96928.1 - 0.1 12.0 0.5 0.29 10.6 0.2 1.7 1 1 0 1 1 1 0 Intracellular multiplication and human macrophage-killing PaO PF08417.12 CDJ96928.1 - 0.13 12.4 0.0 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 Pheophorbide a oxygenase DEAD PF00270.29 CDJ96929.1 - 7.9e-47 159.3 0.0 2.5e-46 157.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ96929.1 - 1.1e-24 87.0 0.0 5.7e-24 84.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 CDJ96929.1 - 5.8e-05 22.0 0.0 8.9e-05 21.4 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 CDJ96929.1 - 0.011 15.7 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit LETM1 PF07766.13 CDJ96930.1 - 3.7e-105 351.1 7.9 3.7e-105 351.1 7.9 3.2 3 1 1 4 4 4 1 LETM1-like protein SAP PF02037.27 CDJ96930.1 - 0.0017 18.1 0.1 0.9 9.4 0.0 4.0 3 0 0 3 3 3 1 SAP domain EF-hand_7 PF13499.6 CDJ96930.1 - 0.73 10.3 5.4 0.64 10.5 0.1 3.6 3 0 0 3 3 3 0 EF-hand domain pair Collagen PF01391.18 CDJ96931.1 - 6.1e-23 80.4 72.2 0.00033 20.3 3.7 4.1 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Herpes_LMP2 PF07415.11 CDJ96931.1 - 2.6 6.7 7.2 3.8 6.2 3.1 2.3 2 0 0 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein Ig_3 PF13927.6 CDJ96932.1 - 6.8e-18 65.1 0.0 4.9e-12 46.3 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 CDJ96932.1 - 3.4e-16 59.1 0.0 8.1e-11 41.8 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 CDJ96932.1 - 3.6e-14 52.9 0.0 5.3e-10 39.5 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 CDJ96932.1 - 7.3e-09 35.7 0.0 0.00098 19.3 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 CDJ96932.1 - 2.6e-07 30.8 2.1 0.098 12.8 0.0 3.6 3 1 0 4 4 3 3 Immunoglobulin V-set domain Izumo-Ig PF16706.5 CDJ96932.1 - 0.0086 16.1 0.0 0.86 9.7 0.0 2.5 2 1 0 2 2 2 1 Izumo-like Immunoglobulin domain Comm PF15957.5 CDJ96932.1 - 0.022 15.1 0.2 0.039 14.3 0.2 1.3 1 0 0 1 1 1 0 Commissureless Dpy19 PF10034.9 CDJ96932.1 - 0.039 12.2 0.1 0.05 11.8 0.1 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Orthoreo_P10 PF07204.11 CDJ96932.1 - 0.041 13.8 0.2 0.097 12.6 0.2 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 SIT PF15330.6 CDJ96932.1 - 0.052 14.0 0.2 0.052 14.0 0.2 1.9 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT C2-set_2 PF08205.12 CDJ96932.1 - 0.073 13.1 0.0 0.27 11.3 0.0 1.9 1 1 1 2 2 2 0 CD80-like C2-set immunoglobulin domain TMEM154 PF15102.6 CDJ96932.1 - 0.08 12.8 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family SCIMP PF15050.6 CDJ96932.1 - 0.089 13.3 0.3 0.2 12.1 0.3 1.5 1 0 0 1 1 1 0 SCIMP protein DUF2207 PF09972.9 CDJ96932.1 - 0.098 11.4 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Phytoreo_S7 PF07236.11 CDJ96932.1 - 0.17 10.2 0.0 0.23 9.8 0.0 1.1 1 0 0 1 1 1 0 Phytoreovirus S7 protein Cpn60_TCP1 PF00118.24 CDJ96933.1 - 4.1e-158 527.1 2.1 4.6e-158 526.9 2.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Beta_helix_2 PF18835.1 CDJ96933.1 - 0.0049 16.6 0.0 0.041 13.6 0.0 2.3 2 0 0 2 2 2 1 Beta helix repeat of Inulin fructotransferase Acetyltransf_10 PF13673.7 CDJ96934.1 - 1.1e-06 28.6 0.0 1.8e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDJ96934.1 - 1.6e-06 28.4 0.0 2.7e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CDJ96934.1 - 9.1e-06 25.6 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 CDJ96934.1 - 3e-05 24.3 0.0 5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CDJ96934.1 - 0.0013 19.4 0.1 0.015 16.0 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CDJ96934.1 - 0.002 18.2 0.0 0.0063 16.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CDJ96934.1 - 0.0071 16.4 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF4726 PF15855.5 CDJ96934.1 - 0.2 11.9 0.2 0.51 10.6 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4726) DUF1757 PF08560.10 CDJ96935.1 - 2.3e-44 151.0 0.0 2.8e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) ATP-synt_I PF03899.15 CDJ96935.1 - 0.11 12.8 0.4 0.43 11.0 0.0 1.9 2 0 0 2 2 2 0 ATP synthase I chain RIBIOP_C PF04950.12 CDJ96936.1 - 2.1e-92 309.7 0.3 2.1e-92 309.7 0.3 1.9 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CDJ96936.1 - 6e-30 103.2 0.0 1.7e-29 101.7 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 CDJ96936.1 - 4.9e-06 26.2 0.0 0.0003 20.4 0.0 2.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDJ96936.1 - 0.0053 16.8 0.1 0.035 14.2 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.6 CDJ96936.1 - 0.015 15.3 0.1 0.16 12.0 0.1 2.7 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 CDJ96936.1 - 0.048 13.6 0.3 0.4 10.6 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PFK PF00365.20 CDJ96938.1 - 2.1e-173 575.3 2.0 2.1e-97 325.9 0.1 2.0 2 0 0 2 2 2 2 Phosphofructokinase DUF190 PF02641.15 CDJ96938.1 - 0.041 14.2 0.0 3.4 8.0 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized ACR, COG1993 Ferritin PF00210.24 CDJ96938.1 - 0.057 13.4 0.2 0.16 11.9 0.1 1.7 2 0 0 2 2 2 0 Ferritin-like domain Ribosom_S12_S23 PF00164.25 CDJ96938.1 - 0.067 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S12/S23 7TM_GPCR_Srt PF10321.9 CDJ96939.1 - 2.9e-08 33.1 35.7 5.2e-08 32.2 35.7 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt 7TM_GPCR_Srx PF10328.9 CDJ96939.1 - 1.4e-07 31.4 38.5 1.7e-07 31.2 38.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx PMT2_N PF17987.1 CDJ96940.1 - 1.5e-53 180.2 1.7 4.5e-53 178.7 0.9 2.2 3 0 0 3 3 3 1 Phosphoethanolamine N-methyltransferase 2 N-terminal Methyltransf_11 PF08241.12 CDJ96940.1 - 3.4e-25 88.5 0.0 1.2e-22 80.3 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ96940.1 - 1.1e-22 80.5 0.1 3.8e-21 75.6 0.0 3.0 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ96940.1 - 1.3e-20 73.7 0.7 3.8e-17 62.5 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain CMAS PF02353.20 CDJ96940.1 - 6.9e-19 68.2 0.1 2.9e-17 62.9 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 CDJ96940.1 - 1.2e-16 61.0 0.0 8.3e-16 58.3 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ96940.1 - 2e-16 60.5 0.3 1.7e-15 57.5 0.0 2.6 3 1 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ96940.1 - 1.7e-14 53.7 0.2 7.1e-14 51.7 0.0 2.0 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.12 CDJ96940.1 - 1.6e-07 31.1 0.0 2.6e-05 23.8 0.0 2.5 2 1 0 2 2 2 1 AdoMet dependent proline di-methyltransferase MTS PF05175.14 CDJ96940.1 - 2.7e-05 23.8 0.0 0.0061 16.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.18 CDJ96940.1 - 6.7e-05 22.3 0.1 0.00018 20.9 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_9 PF08003.11 CDJ96940.1 - 0.00048 19.1 0.0 0.00085 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) AP_endonuc_2 PF01261.24 CDJ96940.1 - 0.00066 19.2 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel MetW PF07021.12 CDJ96940.1 - 0.00067 19.3 0.1 0.0028 17.3 0.0 2.1 3 0 0 3 3 3 1 Methionine biosynthesis protein MetW DREV PF05219.12 CDJ96940.1 - 0.00078 18.6 0.0 0.002 17.3 0.0 1.6 1 1 0 1 1 1 1 DREV methyltransferase DOT1 PF08123.13 CDJ96940.1 - 0.0016 18.0 0.2 0.0061 16.1 0.0 2.0 2 0 0 2 2 2 1 Histone methylation protein DOT1 CheR PF01739.18 CDJ96940.1 - 0.0024 17.4 0.0 0.04 13.4 0.0 2.3 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Bin3 PF06859.12 CDJ96940.1 - 0.0075 16.9 1.2 4.5 8.0 0.4 3.1 2 1 0 2 2 2 1 Bicoid-interacting protein 3 (Bin3) PCMT PF01135.19 CDJ96940.1 - 0.016 15.0 0.0 0.036 13.8 0.0 1.7 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TENA_THI-4 PF03070.16 CDJ96940.1 - 0.063 13.1 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 TENA/THI-4/PQQC family ADH_zinc_N PF00107.26 CDJ96940.1 - 0.077 13.0 0.0 0.24 11.4 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Sigma70_r1_1 PF03979.14 CDJ96940.1 - 1.3 9.2 4.2 13 5.9 0.1 2.4 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 ERAP1_C PF11838.8 CDJ96941.1 - 1.4e-56 192.3 0.7 2.3e-56 191.6 0.7 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 CDJ96941.1 - 1.4e-46 158.8 0.1 2.2e-46 158.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CDJ96941.1 - 4.3e-24 85.7 0.0 6.2e-17 62.4 0.0 3.1 3 0 0 3 3 3 2 Peptidase M1 N-terminal domain TPR_MLP1_2 PF07926.12 CDJ96941.1 - 0.02 14.9 1.8 0.044 13.8 1.8 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF851 PF05867.11 CDJ96942.1 - 1.5e-05 24.6 0.2 1.5e-05 24.6 0.2 2.6 3 1 0 3 3 3 1 Protein of unknown function (DUF851) Hanta_G1 PF01567.16 CDJ96942.1 - 0.22 10.2 1.2 0.34 9.5 1.2 1.2 1 0 0 1 1 1 0 Hantavirus glycoprotein G1 NKAIN PF05640.14 CDJ96944.1 - 0.31 10.2 0.0 0.46 9.7 0.0 1.1 1 0 0 1 1 1 0 Na,K-Atpase Interacting protein GHMP_kinases_C PF08544.13 CDJ96946.1 - 0.33 11.3 2.0 0.46 10.9 2.0 1.1 1 0 0 1 1 1 0 GHMP kinases C terminal GHMP_kinases_C PF08544.13 CDJ96947.1 - 0.19 12.1 2.8 0.26 11.7 2.8 1.1 1 0 0 1 1 1 0 GHMP kinases C terminal Totivirus_coat PF05518.11 CDJ96953.1 - 0.3 9.1 8.7 0.32 9.0 8.7 1.0 1 0 0 1 1 1 0 Totivirus coat protein Metallophos PF00149.28 CDJ96954.1 - 4.2e-34 118.8 0.0 6.3e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDJ96954.1 - 4.2e-09 36.7 0.0 7.2e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DAG1 PF05454.11 CDJ96955.1 - 0.026 13.9 0.0 0.029 13.7 0.0 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Pox_D5 PF03288.16 CDJ96955.1 - 0.093 13.2 0.3 0.13 12.7 0.3 1.2 1 0 0 1 1 1 0 Poxvirus D5 protein-like GAPT PF11770.8 CDJ96955.1 - 2.4 8.0 4.1 17 5.2 1.7 2.1 1 1 1 2 2 2 0 GRB2-binding adapter (GAPT) PALP PF00291.25 CDJ96956.1 - 2.8e-66 223.9 3.3 2.8e-66 223.9 3.3 1.3 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme ACT_4 PF13291.6 CDJ96956.1 - 0.00016 22.2 0.0 0.00033 21.2 0.0 1.5 1 0 0 1 1 1 1 ACT domain PAP2_C PF14360.6 CDJ96957.1 - 1.3e-24 86.5 9.5 1.3e-24 86.5 9.5 2.5 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2 PF01569.21 CDJ96957.1 - 3.2e-06 27.0 6.1 3.2e-06 27.0 6.1 2.4 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 CDJ96957.1 - 0.00039 20.1 9.3 0.00071 19.3 9.3 1.4 1 0 0 1 1 1 1 PAP2 superfamily PMEI PF04043.15 CDJ96958.1 - 0.019 15.3 0.5 0.054 13.8 0.5 1.8 1 1 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor LANC_like PF05147.13 CDJ96959.1 - 2.1e-59 200.9 0.0 2.6e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein TED_complement PF07678.14 CDJ96959.1 - 0.064 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 A-macroglobulin TED domain Glyco_hydro_127 PF07944.12 CDJ96959.1 - 0.26 9.8 0.0 0.36 9.3 0.0 1.2 1 0 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_30 PF02055.16 CDJ96960.1 - 9e-148 491.9 2.0 1.1e-147 491.6 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 CDJ96960.1 - 5.2e-06 25.9 0.1 1.3e-05 24.6 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30C PF17189.4 CDJ96960.1 - 0.00025 21.2 3.3 0.00066 19.8 3.3 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain DUF2197 PF09963.9 CDJ96961.1 - 0.043 14.1 1.4 1.9 8.8 0.2 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-C2H2_2 PF12756.7 CDJ96961.1 - 0.052 13.9 0.2 0.077 13.3 0.2 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) GYF PF02213.16 CDJ96962.1 - 2e-19 69.0 0.3 1.7e-09 37.2 0.1 2.7 2 1 0 2 2 2 2 GYF domain FYVE PF01363.21 CDJ96963.1 - 3.3e-14 52.8 6.8 4.4e-14 52.4 6.8 1.2 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CDJ96963.1 - 0.0049 17.1 1.7 0.0056 16.9 1.7 1.2 1 0 0 1 1 1 1 FYVE-type zinc finger Ephrin_rec_like PF07699.13 CDJ96963.1 - 0.038 13.8 0.6 0.038 13.8 0.6 2.0 1 1 1 2 2 2 0 Putative ephrin-receptor like zf-B_box PF00643.24 CDJ96963.1 - 0.077 13.2 5.8 0.2 11.8 5.8 1.7 1 1 0 1 1 1 0 B-box zinc finger DUF35_N PF12172.8 CDJ96963.1 - 3.8 7.5 11.7 4.6 7.2 0.4 2.7 2 1 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF3486 PF11985.8 CDJ96964.1 - 0.00021 21.8 0.4 0.0003 21.3 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3486) zf-C2H2_2 PF12756.7 CDJ96964.1 - 0.0074 16.6 3.8 0.0074 16.6 3.8 2.4 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CDJ96964.1 - 0.014 15.8 4.1 0.014 15.8 4.1 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type SF3a60_bindingd PF12108.8 CDJ96964.1 - 0.1 12.5 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Spectrin PF00435.21 CDJ96965.1 - 4.7e-05 23.8 7.8 0.00078 19.9 4.4 2.5 1 1 1 2 2 2 2 Spectrin repeat OmpH PF03938.14 CDJ96965.1 - 0.0023 18.3 0.3 0.0023 18.3 0.3 1.8 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) SOAR PF16533.5 CDJ96965.1 - 0.0023 17.9 4.5 0.29 11.1 0.2 3.1 1 1 2 3 3 3 1 STIM1 Orai1-activating region DUF4201 PF13870.6 CDJ96965.1 - 0.0053 16.5 2.4 0.008 15.9 2.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Lebercilin PF15619.6 CDJ96965.1 - 0.0081 15.8 5.7 0.012 15.2 2.9 2.1 1 1 1 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease BLOC1_2 PF10046.9 CDJ96965.1 - 0.028 14.7 1.4 0.26 11.6 0.2 2.6 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.11 CDJ96965.1 - 0.042 14.2 5.9 1.6 9.2 0.2 4.0 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) Exonuc_VII_L PF02601.15 CDJ96965.1 - 0.073 12.6 2.0 0.091 12.3 2.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Laminin_II PF06009.12 CDJ96965.1 - 0.087 12.8 2.6 0.17 11.9 0.9 2.1 1 1 1 2 2 2 0 Laminin Domain II GAS PF13851.6 CDJ96965.1 - 0.09 12.1 4.3 0.23 10.8 2.0 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 CDJ96965.1 - 0.11 12.7 9.6 0.43 10.8 9.3 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 CDJ96965.1 - 0.12 12.9 14.0 0.38 11.3 13.3 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region Phage_GPO PF05929.11 CDJ96965.1 - 0.16 11.6 1.7 0.27 10.8 1.7 1.5 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase FUSC PF04632.12 CDJ96965.1 - 2.3 6.7 9.1 2.7 6.4 9.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Jnk-SapK_ap_N PF09744.9 CDJ96965.1 - 5 7.3 12.0 24 5.1 0.6 2.7 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 DUF4140 PF13600.6 CDJ96965.1 - 9 6.8 7.9 4 7.9 0.3 3.0 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) SlyX PF04102.12 CDJ96965.1 - 9.4 6.9 8.2 24 5.6 2.5 3.4 1 1 1 3 3 3 0 SlyX HR1 PF02185.16 CDJ96965.1 - 9.6 6.4 8.9 27 5.0 4.4 3.3 2 1 1 3 3 3 0 Hr1 repeat 7TM_GPCR_Srsx PF10320.9 CDJ96966.1 - 2.2e-37 128.8 8.3 2.7e-37 128.6 8.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx LptF_LptG PF03739.14 CDJ96966.1 - 0.14 11.0 7.7 0.91 8.3 4.9 2.2 2 1 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG DUF4693 PF15764.5 CDJ96967.1 - 0.022 14.3 0.7 0.027 14.1 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4693) Diphthamide_syn PF01866.17 CDJ96967.1 - 0.15 11.5 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Putative diphthamide synthesis protein SET PF00856.28 CDJ96968.1 - 2.9e-36 125.4 4.5 8.1e-21 75.1 0.5 3.9 2 2 0 2 2 2 2 SET domain SH3_1 PF00018.28 CDJ96968.1 - 3.6e-15 55.3 0.0 1.2e-10 40.8 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH2 PF00017.24 CDJ96968.1 - 4.3e-15 55.6 0.2 1.7e-14 53.6 0.0 2.1 3 0 0 3 3 3 1 SH2 domain SH3_9 PF14604.6 CDJ96968.1 - 4.5e-14 52.0 0.0 1e-09 38.1 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 CDJ96968.1 - 7.9e-14 51.1 0.1 3.8e-07 29.7 0.0 2.8 2 0 0 2 2 2 2 Variant SH3 domain Pre-SET PF05033.16 CDJ96968.1 - 4e-09 37.1 24.9 9.6e-07 29.4 11.6 3.1 3 0 0 3 3 3 2 Pre-SET motif DUF4119 PF13494.6 CDJ96968.1 - 0.0035 17.4 0.0 5.1 7.3 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function, B. Theta Gene description (DUF4119) GATase_7 PF13537.6 CDJ96968.1 - 0.02 14.8 0.1 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 Glutamine amidotransferase domain GCM PF03615.15 CDJ96968.1 - 0.053 13.4 4.5 3.3 7.6 0.2 3.0 2 0 0 2 2 2 0 GCM motif protein DUF4407 PF14362.6 CDJ96969.1 - 8 5.7 10.3 14 4.9 10.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ank_4 PF13637.6 CDJ96970.1 - 3.3e-64 212.5 37.6 5.8e-10 39.5 0.1 10.5 1 1 11 12 12 12 12 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ96970.1 - 9.2e-61 202.4 21.8 6.5e-13 49.1 0.4 6.8 1 1 6 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ96970.1 - 1.8e-58 192.5 35.7 1.9e-05 24.9 0.6 13.1 13 0 0 13 13 13 11 Ankyrin repeat Ank_3 PF13606.6 CDJ96970.1 - 2.7e-49 159.4 21.5 0.00062 20.0 0.2 13.1 13 0 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.6 CDJ96970.1 - 1e-44 150.0 25.2 7.1e-08 32.6 0.2 9.1 2 2 6 9 9 9 9 Ankyrin repeats (many copies) ubiquitin PF00240.23 CDJ96975.1 - 2.9e-08 33.4 0.0 6.4e-08 32.2 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family zf-AN1 PF01428.16 CDJ96975.1 - 1.2e-05 25.3 7.7 1.2e-05 25.3 7.7 2.3 2 0 0 2 2 2 1 AN1-like Zinc finger TerY_C PF15616.6 CDJ96975.1 - 0.014 15.5 1.0 0.027 14.6 1.0 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain DUF148 PF02520.17 CDJ96977.1 - 1.3e-22 79.9 5.6 2.2e-22 79.2 5.6 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF148 Baculo_PEP_C PF04513.12 CDJ96977.1 - 0.0066 16.5 0.0 0.0086 16.1 0.0 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF241 PF03087.14 CDJ96977.1 - 0.0083 16.0 0.8 0.0099 15.7 0.8 1.1 1 0 0 1 1 1 1 Arabidopsis protein of unknown function Stirrup PF09061.6 CDJ96977.1 - 0.1 12.8 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 Stirrup Acetyltransf_11 PF13720.6 CDJ96977.1 - 0.16 12.4 1.2 4.1 7.9 0.1 2.3 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 BSP_II PF05432.11 CDJ96977.1 - 0.96 9.1 8.2 1.3 8.6 8.2 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF148 PF02520.17 CDJ96978.1 - 3.1e-22 78.8 6.3 4.9e-22 78.1 6.3 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF148 Baculo_PEP_C PF04513.12 CDJ96978.1 - 0.023 14.7 0.1 0.033 14.2 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF241 PF03087.14 CDJ96978.1 - 0.053 13.3 0.7 0.076 12.8 0.7 1.2 1 0 0 1 1 1 0 Arabidopsis protein of unknown function NB-ARC PF00931.22 CDJ96978.1 - 0.06 12.5 0.3 0.091 11.9 0.3 1.2 1 0 0 1 1 1 0 NB-ARC domain Caldesmon PF02029.15 CDJ96981.1 - 0.015 14.1 23.7 0.019 13.8 23.7 1.0 1 0 0 1 1 1 0 Caldesmon PTPRCAP PF15713.5 CDJ96981.1 - 0.037 14.3 14.4 0.049 13.9 14.4 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Plasmodium_Vir PF05795.11 CDJ96981.1 - 0.1 12.0 2.9 0.1 12.0 2.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DAG_kinase_N PF14513.6 CDJ96981.1 - 0.13 12.4 4.2 0.26 11.5 4.1 1.6 1 1 0 1 1 1 0 Diacylglycerol kinase N-terminus Zip PF02535.22 CDJ96981.1 - 0.36 10.0 4.4 0.46 9.7 4.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC27 PF09507.10 CDJ96981.1 - 0.77 9.1 18.7 0.89 8.9 18.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Asp-B-Hydro_N PF05279.11 CDJ96981.1 - 1.3 9.0 19.7 1.6 8.8 19.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region HSP70 PF00012.20 CDJ96981.1 - 1.7 6.7 10.0 1.9 6.6 10.0 1.2 1 0 0 1 1 1 0 Hsp70 protein CDC45 PF02724.14 CDJ96981.1 - 2 6.6 21.3 2.2 6.5 21.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CDJ96981.1 - 2.1 7.0 12.7 2.4 6.8 12.7 1.3 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 CDJ96981.1 - 2.9 6.6 10.5 3.4 6.4 10.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Exonuc_VII_L PF02601.15 CDJ96981.1 - 4.2 6.8 8.6 5.1 6.6 8.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ALMT PF11744.8 CDJ96981.1 - 4.5 6.0 5.6 4.5 6.0 5.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter AAA_11 PF13086.6 CDJ96981.1 - 6.6 6.4 11.5 8.5 6.1 11.5 1.3 1 0 0 1 1 1 0 AAA domain Dicty_REP PF05086.12 CDJ96981.1 - 7 4.5 13.4 1.1 7.1 9.8 1.5 1 1 1 2 2 2 0 Dictyostelium (Slime Mold) REP protein DDHD PF02862.17 CDJ96981.1 - 7.1 6.7 6.5 9.4 6.3 6.5 1.3 1 0 0 1 1 1 0 DDHD domain FUSC PF04632.12 CDJ96981.1 - 7.6 4.9 9.0 9.6 4.6 9.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family RR_TM4-6 PF06459.12 CDJ96981.1 - 9.1 6.0 15.4 12 5.7 15.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FapA PF03961.13 CDJ96981.1 - 9.5 4.7 8.0 11 4.5 8.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Branch PF02485.21 CDJ96983.1 - 2.6e-21 76.3 0.0 4.3e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme PB1 PF00564.24 CDJ96983.1 - 3.3e-12 46.1 0.1 5.9e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 PB1 domain Exo_endo_phos PF03372.23 CDJ96984.1 - 6e-11 42.3 0.0 9.1e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UBA_4 PF14555.6 CDJ96984.1 - 8.9e-10 38.2 0.4 1.7e-09 37.4 0.4 1.5 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 CDJ96984.1 - 0.041 13.5 0.1 0.082 12.6 0.1 1.5 1 0 0 1 1 1 0 TAP C-terminal domain DUF496 PF04363.12 CDJ96985.1 - 0.014 15.4 0.5 0.022 14.8 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF496) NAD_binding_2 PF03446.15 CDJ96985.1 - 0.019 15.1 0.4 0.021 15.0 0.4 1.1 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Cid2 PF09774.9 CDJ96985.1 - 0.023 15.1 2.0 0.038 14.4 2.0 1.3 1 0 0 1 1 1 0 Caffeine-induced death protein 2 DUF3450 PF11932.8 CDJ96985.1 - 0.032 13.6 1.5 0.044 13.1 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2052 PF09747.9 CDJ96985.1 - 0.041 14.0 0.5 0.057 13.5 0.5 1.4 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) PTS_EIIA_2 PF00359.22 CDJ96985.1 - 0.042 13.8 0.2 0.057 13.3 0.2 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SIS PF01380.22 CDJ96985.1 - 0.049 13.5 0.2 0.065 13.1 0.2 1.2 1 0 0 1 1 1 0 SIS domain NPV_P10 PF05531.12 CDJ96985.1 - 0.11 13.0 3.1 0.19 12.2 3.0 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF919 PF06034.11 CDJ96985.1 - 0.12 12.2 1.0 0.22 11.4 1.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Pkinase PF00069.25 CDJ96986.1 - 4.6e-61 206.5 0.0 5.3e-61 206.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ96986.1 - 5.1e-43 147.2 0.0 6.3e-43 146.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ96986.1 - 2.9e-07 30.1 0.0 2.8e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.11 CDJ96986.1 - 0.0068 15.5 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 CDJ96986.1 - 0.069 12.5 0.1 0.099 12.0 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDJ96986.1 - 0.17 10.6 0.1 0.24 10.1 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase PB1 PF00564.24 CDJ96987.1 - 9.7e-06 25.4 0.0 0.00012 21.9 0.0 2.0 2 0 0 2 2 2 1 PB1 domain zf_C2H2_13 PF18508.1 CDJ96987.1 - 0.078 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Zinc finger domain CHGN PF05679.16 CDJ96988.1 - 1.5e-125 419.9 0.0 3.4e-125 418.8 0.0 1.5 1 1 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 CDJ96988.1 - 6.3e-14 52.0 0.0 1e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Fringe-like Glyco_transf_7C PF02709.14 CDJ96988.1 - 5.2e-08 32.4 0.1 1.5e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CDJ96988.1 - 7.7e-08 32.1 0.1 4.6e-07 29.6 0.1 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CDJ96988.1 - 0.003 17.4 0.1 0.96 9.2 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Galactosyl_T PF01762.21 CDJ96988.1 - 0.025 14.4 0.0 0.27 11.0 0.0 2.5 3 0 0 3 3 3 0 Galactosyltransferase rve PF00665.26 CDJ96989.1 - 7.7e-23 80.9 0.0 1.9e-22 79.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDJ96989.1 - 1.7e-05 24.5 0.1 6.1e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain NHase_beta PF02211.15 CDJ96989.1 - 0.037 14.1 0.1 0.79 9.7 0.0 2.1 2 0 0 2 2 2 0 Nitrile hydratase beta subunit Integrase_H2C2 PF17921.1 CDJ96989.1 - 0.043 13.9 0.4 0.078 13.1 0.4 1.4 1 0 0 1 1 1 0 Integrase zinc binding domain RT_RNaseH PF17917.1 CDJ96990.1 - 1.2e-67 224.7 0.0 1.1e-32 112.5 0.0 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ96990.1 - 2.5e-67 223.2 0.3 3.3e-36 123.3 0.0 3.3 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase DIE2_ALG10 PF04922.12 CDJ96990.1 - 7.9e-26 91.2 0.4 1.6e-25 90.2 0.4 1.5 1 0 0 1 1 1 1 DIE2/ALG10 family RVT_1 PF00078.27 CDJ96990.1 - 3.2e-21 75.9 0.0 6.2e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ96990.1 - 8.5e-18 64.2 0.2 2.7e-17 62.6 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CDJ96990.1 - 0.018 15.3 0.1 0.046 13.9 0.1 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Frizzled PF01534.17 CDJ96991.1 - 8.3e-95 317.5 17.4 8.3e-95 317.5 17.4 1.5 2 0 0 2 2 2 1 Frizzled/Smoothened family membrane region Fz PF01392.22 CDJ96991.1 - 4.6e-31 107.7 3.8 1.3e-30 106.2 3.8 1.8 1 0 0 1 1 1 1 Fz domain Diphthamide_syn PF01866.17 CDJ96993.1 - 9.3e-33 113.9 0.0 1.3e-32 113.5 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Collagen PF01391.18 CDJ96994.1 - 4.4e-21 74.4 69.1 1.9e+02 1.9 69.1 3.1 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Collagen PF01391.18 CDJ96995.1 - 1.1e-24 85.9 76.6 1.8e+04 -8.2 73.5 4.2 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ96995.1 - 5.4e-08 32.8 0.7 7e-08 32.4 0.7 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Diphthamide_syn PF01866.17 CDJ96996.1 - 3.4e-23 82.6 0.2 3.9e-23 82.3 0.2 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein EF-hand_1 PF00036.32 CDJ96997.1 - 2.1e-08 33.1 5.6 0.0086 15.6 0.1 3.7 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 CDJ96997.1 - 1.4e-07 31.9 4.1 0.0019 18.6 1.0 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ96997.1 - 1e-05 24.8 6.1 0.0029 17.1 0.2 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CDJ96997.1 - 1.3e-05 24.7 5.7 0.024 14.5 0.1 3.8 3 0 0 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CDJ96997.1 - 2e-05 24.8 0.6 0.00054 20.3 0.2 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region HSF_DNA-bind PF00447.17 CDJ96998.1 - 1.7e-28 99.0 0.3 4e-28 97.9 0.3 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding ZYG-11_interact PF05884.12 CDJ96998.1 - 0.0014 18.1 3.6 0.053 12.9 3.3 2.2 2 0 0 2 2 2 1 Interactor of ZYG-11 LRRFIP PF09738.9 CDJ96998.1 - 0.0034 16.9 1.7 0.0065 16.0 1.7 1.4 1 0 0 1 1 1 1 LRRFIP family TMF_DNA_bd PF12329.8 CDJ96998.1 - 0.029 14.3 3.2 0.072 13.1 3.2 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Speriolin_N PF15058.6 CDJ96998.1 - 0.086 12.9 4.6 0.19 11.8 4.6 1.5 1 0 0 1 1 1 0 Speriolin N terminus GIT_CC PF16559.5 CDJ96998.1 - 5.7 6.9 10.5 4.6 7.2 6.0 2.6 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Btz PF09405.10 CDJ97000.1 - 3.4e-13 50.0 9.8 3.4e-13 50.0 9.8 5.9 2 1 1 3 3 3 1 CASC3/Barentsz eIF4AIII binding Ribosomal_L14e PF01929.17 CDJ97001.1 - 3.8e-24 85.0 8.5 6.1e-24 84.3 8.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 CDJ97001.1 - 0.0038 17.1 3.6 0.0086 16.0 3.6 1.7 1 0 0 1 1 1 1 KOW motif Sec23_trunk PF04811.15 CDJ97004.1 - 7.8e-24 84.6 0.0 9.1e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain DEC-1_N PF04625.13 CDJ97004.1 - 0.057 12.4 3.1 0.061 12.3 3.1 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region ExbD PF02472.16 CDJ97006.1 - 0.019 15.1 0.4 0.026 14.7 0.4 1.4 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR DUF3246 PF11596.8 CDJ97006.1 - 0.073 12.5 0.5 0.094 12.1 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Mito_fiss_reg PF05308.11 CDJ97006.1 - 1.4 9.0 9.9 2 8.4 9.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Hamartin PF04388.12 CDJ97006.1 - 1.7 7.2 6.7 1.6 7.3 6.7 1.0 1 0 0 1 1 1 0 Hamartin protein PGM_PMM_I PF02878.16 CDJ97007.1 - 1.1e-17 64.0 0.2 1.3e-09 37.9 0.0 2.7 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 CDJ97007.1 - 0.015 15.5 0.1 0.029 14.6 0.1 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CDJ97007.1 - 0.018 15.7 0.9 0.31 11.7 0.2 3.2 3 1 0 3 3 3 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Pkinase PF00069.25 CDJ97008.1 - 2.7e-75 253.2 0.0 3.7e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CaMKII_AD PF08332.10 CDJ97008.1 - 2e-42 144.4 0.0 4.2e-42 143.3 0.0 1.5 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain Pkinase_Tyr PF07714.17 CDJ97008.1 - 1.7e-33 116.1 0.0 2.3e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ97008.1 - 0.0045 15.8 0.0 0.01 14.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase SnoaL_3 PF13474.6 CDJ97008.1 - 0.0049 17.1 0.0 0.0091 16.2 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain APH PF01636.23 CDJ97008.1 - 0.0049 16.8 0.1 0.98 9.3 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ97008.1 - 0.0061 15.9 0.9 0.055 12.8 0.1 2.5 2 1 1 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CDJ97008.1 - 0.03 13.8 0.0 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF4440 PF14534.6 CDJ97008.1 - 0.046 14.1 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Palm_thioest PF02089.15 CDJ97009.1 - 1e-40 140.1 0.7 1.2e-40 139.9 0.7 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Amidase PF01425.21 CDJ97010.1 - 0.0001 21.4 0.0 0.00011 21.3 0.0 1.0 1 0 0 1 1 1 1 Amidase Mg_trans_NIPA PF05653.14 CDJ97011.1 - 5.3e-41 140.7 2.8 6.1e-41 140.5 2.8 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA DUF1282 PF06930.12 CDJ97011.1 - 0.038 13.8 1.1 0.064 13.0 1.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) Tubulin PF00091.25 CDJ97012.1 - 2.5e-63 213.8 0.1 4.3e-63 213.1 0.1 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDJ97012.1 - 1e-25 90.3 0.2 2.3e-25 89.2 0.2 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 CDJ97012.1 - 0.045 13.0 0.0 0.078 12.2 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Misat_Tub_SegII PF10644.9 CDJ97012.1 - 0.096 13.0 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CDJ97012.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain RNA_pol_L_2 PF13656.6 CDJ97013.1 - 1e-22 79.7 0.0 1.3e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CDJ97013.1 - 2.6e-08 33.1 0.0 3.5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain UQ_con PF00179.26 CDJ97014.1 - 3.2e-50 169.4 0.0 3.7e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CDJ97014.1 - 0.056 13.7 0.0 0.068 13.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain Syntaxin PF00804.25 CDJ97015.1 - 8.3e-64 215.0 9.6 8.3e-64 215.0 9.6 1.8 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 CDJ97015.1 - 4.4e-19 68.2 10.1 6e-19 67.8 6.0 3.1 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 CDJ97015.1 - 3.2e-11 43.5 0.9 3.2e-11 43.5 0.9 2.7 2 1 0 2 2 2 1 Syntaxin-like protein Synaptobrevin PF00957.21 CDJ97015.1 - 0.0037 17.0 4.8 0.0037 17.0 4.8 2.2 3 0 0 3 3 2 1 Synaptobrevin Syntaxin-6_N PF09177.11 CDJ97015.1 - 0.013 16.0 4.6 0.024 15.2 0.4 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Sigma_reg_N PF13800.6 CDJ97015.1 - 0.016 15.5 1.4 0.041 14.2 1.4 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal ODV-E18 PF10717.9 CDJ97015.1 - 0.043 13.7 0.5 0.092 12.6 0.5 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Lzipper-MIP1 PF14389.6 CDJ97015.1 - 0.069 13.4 0.1 0.71 10.2 0.0 2.3 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Sec34 PF04136.15 CDJ97015.1 - 0.071 13.0 2.6 3.8 7.4 0.3 2.7 2 0 0 2 2 2 0 Sec34-like family LRRC37AB_C PF14914.6 CDJ97015.1 - 0.071 13.0 2.6 0.16 11.8 2.6 1.6 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DUF2508 PF10704.9 CDJ97015.1 - 0.076 13.2 1.3 1.4 9.1 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) ABC2_membrane_3 PF12698.7 CDJ97015.1 - 0.13 11.4 0.2 0.27 10.3 0.2 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein Lge1 PF11488.8 CDJ97015.1 - 0.15 12.3 1.6 0.87 9.8 0.2 2.6 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 ETRAMP PF09716.10 CDJ97015.1 - 0.2 11.7 5.6 0.042 13.9 1.0 2.3 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) LMBR1 PF04791.16 CDJ97015.1 - 0.24 10.3 8.4 0.48 9.3 8.4 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein T2SSF PF00482.23 CDJ97015.1 - 0.24 11.3 3.7 0.6 10.1 2.8 2.0 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF2207 PF09972.9 CDJ97015.1 - 0.32 9.7 3.8 0.9 8.2 3.8 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) MCPsignal PF00015.21 CDJ97015.1 - 0.32 10.8 8.1 0.5 10.2 0.4 3.1 2 2 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Baculo_11_kDa PF06143.11 CDJ97015.1 - 0.37 10.4 3.1 1 9.0 3.1 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family Anoctamin PF04547.12 CDJ97015.1 - 0.41 9.4 2.2 0.36 9.6 0.4 1.6 1 1 1 2 2 2 0 Calcium-activated chloride channel Pox_EPC_I2-L1 PF12575.8 CDJ97015.1 - 0.45 10.8 2.1 2.1 8.7 1.1 2.4 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 DUF3139 PF11337.8 CDJ97015.1 - 0.45 11.2 3.6 1.3 9.7 3.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) Dna2 PF08696.11 CDJ97015.1 - 0.46 10.3 5.7 0.5 10.1 0.6 2.6 1 1 2 3 3 3 0 DNA replication factor Dna2 Herpes_US9 PF06072.11 CDJ97015.1 - 1 9.3 6.9 0.27 11.1 0.6 2.8 3 0 0 3 3 2 0 Alphaherpesvirus tegument protein US9 COG5 PF10392.9 CDJ97015.1 - 1.1 9.5 5.0 15 5.8 0.3 2.5 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF148 PF02520.17 CDJ97015.1 - 1.1 9.4 6.5 0.36 10.9 1.5 2.6 3 0 0 3 3 2 0 Domain of unknown function DUF148 DUF948 PF06103.11 CDJ97015.1 - 1.2 9.4 11.1 1.3 9.3 0.3 3.5 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF745 PF05335.13 CDJ97015.1 - 1.4 8.6 8.0 2.3 7.9 1.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF745) UPF0258 PF06789.12 CDJ97015.1 - 1.6 8.8 7.0 3.4 7.8 7.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) DUF2205 PF10224.9 CDJ97015.1 - 1.8 8.6 7.5 0.21 11.6 0.3 2.9 3 1 0 3 3 2 0 Short coiled-coil protein YtxH PF12732.7 CDJ97015.1 - 2 9.0 5.0 6.5 7.4 0.2 3.1 2 2 0 2 2 2 0 YtxH-like protein YabA PF06156.13 CDJ97015.1 - 2.1 9.0 7.3 8.1 7.1 0.4 3.0 2 1 1 3 3 3 0 Initiation control protein YabA Vpu PF00558.19 CDJ97015.1 - 2.8 7.8 7.0 0.51 10.1 1.8 2.5 3 0 0 3 3 3 0 Vpu protein Fib_alpha PF08702.10 CDJ97015.1 - 3.8 7.7 10.1 5.5 7.2 2.6 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Occludin_ELL PF07303.13 CDJ97015.1 - 3.9 8.3 8.5 3 8.6 0.9 2.9 3 0 0 3 3 2 0 Occludin homology domain Fez1 PF06818.15 CDJ97015.1 - 4.8 7.6 11.8 0.93 9.9 0.3 2.8 2 1 0 2 2 2 0 Fez1 ERp29 PF07749.12 CDJ97015.1 - 6.5 7.7 8.6 0.34 11.8 0.5 2.9 3 1 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain RecG_N PF17190.4 CDJ97015.1 - 6.9 7.5 7.9 0.97 10.2 0.9 3.0 3 0 0 3 3 3 0 RecG N-terminal helical domain WD40 PF00400.32 CDJ97016.1 - 1.5e-11 44.6 12.3 0.005 17.7 0.5 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CDJ97016.1 - 0.0039 16.2 1.0 1.1 8.2 0.0 2.9 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein SsgA PF04686.12 CDJ97016.1 - 0.0055 16.7 0.2 4.7 7.3 0.0 3.1 2 1 1 3 3 3 2 Streptomyces sporulation and cell division protein, SsgA DUF4459 PF14673.6 CDJ97016.1 - 0.0082 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4459) PGM_PMM_I PF02878.16 CDJ97017.1 - 2.5e-38 130.9 0.0 5.1e-38 129.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 CDJ97017.1 - 2e-20 73.3 0.0 6.2e-20 71.7 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 CDJ97017.1 - 6.7e-12 45.6 0.0 1.2e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 CDJ97017.1 - 2e-08 34.3 0.0 6.9e-08 32.6 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain fn3 PF00041.21 CDJ97018.1 - 1.8e-22 79.5 0.3 1.8e-10 41.0 0.1 3.4 3 0 0 3 3 3 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CDJ97018.1 - 0.00093 19.7 0.0 8.2 7.1 0.0 4.0 3 2 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain fn3_4 PF16794.5 CDJ97018.1 - 0.002 18.0 0.0 2.8 7.9 0.0 3.4 4 0 0 4 4 4 2 Fibronectin-III type domain RRM_DME PF15628.6 CDJ97020.1 - 0.011 15.8 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 RRM in Demeter Hydrolase PF00702.26 CDJ97020.1 - 0.066 13.5 0.0 0.094 13.0 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDJ97021.1 - 2e-20 72.7 0.0 2.9e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Pkinase PF00069.25 CDJ97028.1 - 2.1e-68 230.6 0.0 3e-68 230.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ97028.1 - 2.8e-27 95.6 0.0 4e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CDJ97028.1 - 1.5e-05 25.4 0.0 3.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 CDJ97028.1 - 0.0026 16.6 0.0 0.0057 15.5 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDJ97028.1 - 0.0068 15.7 0.0 0.0099 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YccJ PF13993.6 CDJ97028.1 - 0.031 14.6 0.1 0.08 13.3 0.1 1.6 1 0 0 1 1 1 0 YccJ-like protein Rsc14 PF08586.10 CDJ97028.1 - 0.15 12.9 0.2 0.71 10.7 0.1 2.1 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Arrestin_C PF02752.22 CDJ97030.1 - 1.9e-13 51.0 0.2 6.1e-12 46.2 0.2 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CDJ97030.1 - 5.9e-08 32.9 0.4 1.8e-05 24.8 0.0 2.7 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain DLH PF01738.18 CDJ97031.1 - 6.1e-48 163.2 0.0 7e-48 163.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 CDJ97031.1 - 2e-06 27.9 0.2 0.0012 18.8 0.0 2.4 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 CDJ97031.1 - 2.1e-06 27.4 0.7 0.0049 16.4 0.1 2.6 1 1 1 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 CDJ97031.1 - 0.00017 20.4 0.1 0.00046 18.9 0.1 1.5 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 CDJ97031.1 - 0.01 15.1 1.2 0.29 10.4 0.3 2.2 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 CDJ97031.1 - 0.034 14.0 0.0 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 CDJ97031.1 - 0.037 14.6 2.6 0.076 13.6 2.3 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF1100 PF06500.11 CDJ97031.1 - 0.043 12.6 0.0 0.058 12.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_1 PF00561.20 CDJ97031.1 - 0.088 12.4 0.0 0.19 11.4 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Voltage_CLC PF00654.20 CDJ97032.1 - 1.6e-55 188.8 33.8 3e-49 168.2 19.8 3.0 1 1 2 3 3 3 2 Voltage gated chloride channel CBS PF00571.28 CDJ97032.1 - 2e-07 31.4 0.6 0.0068 16.8 0.2 2.6 2 0 0 2 2 2 2 CBS domain HILPDA PF15220.6 CDJ97032.1 - 0.2 11.8 0.5 0.79 9.9 0.5 2.0 1 0 0 1 1 1 0 Hypoxia-inducible lipid droplet-associated DUF4064 PF13273.6 CDJ97032.1 - 1.3 9.3 9.7 2.4 8.5 0.5 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Pkinase PF00069.25 CDJ97033.1 - 5.7e-08 32.4 0.3 7.9e-06 25.4 0.2 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ97033.1 - 0.027 13.7 0.1 0.037 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF5346 PF17281.2 CDJ97034.1 - 1.4e-55 185.6 20.5 1.4e-55 185.6 20.5 1.5 2 0 0 2 2 2 1 Family of unknown function (DUF5346) RVT_1 PF00078.27 CDJ97035.1 - 7.1e-23 81.3 0.1 1.3e-22 80.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GILT PF03227.16 CDJ97035.1 - 0.05 13.9 0.7 0.18 12.1 0.3 2.0 2 0 0 2 2 2 0 Gamma interferon inducible lysosomal thiol reductase (GILT) EF_TS PF00889.19 CDJ97035.1 - 0.17 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Elongation factor TS Peptidase_M13_N PF05649.13 CDJ97036.1 - 3.2e-112 376.0 6.1 4.2e-112 375.6 6.1 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 CDJ97036.1 - 2.9e-78 262.2 0.2 6.3e-78 261.1 0.2 1.6 1 0 0 1 1 1 1 Peptidase family M13 Crust_neurohorm PF01147.17 CDJ97041.1 - 8.6e-06 25.5 2.9 1.5e-05 24.7 2.9 1.3 1 0 0 1 1 1 1 Crustacean CHH/MIH/GIH neurohormone family RVT_1 PF00078.27 CDJ97042.1 - 1.8e-39 135.5 0.0 3.1e-39 134.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CENP-T_C PF15511.6 CDJ97043.1 - 3.6e-08 33.5 0.1 4.4e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 CDJ97043.1 - 1.8e-05 25.0 0.1 2.4e-05 24.6 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 CDJ97043.1 - 6.9e-05 22.9 0.1 9.7e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CDJ97043.1 - 7e-05 23.0 0.1 0.00012 22.3 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDJ97043.1 - 0.00023 21.5 0.2 0.00026 21.3 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 CDJ97043.1 - 0.0036 17.3 0.0 0.0055 16.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 CDJ97043.1 - 0.009 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone_H2A_C PF16211.5 CDJ97044.1 - 1.7e-20 72.4 0.8 1.7e-20 72.4 0.8 1.6 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.24 CDJ97044.1 - 9.2e-16 58.4 0.0 1.1e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CDJ97044.1 - 4.3e-06 26.9 0.0 5.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 CDJ97045.1 - 2.3e-08 34.1 0.0 2.9e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 CDJ97045.1 - 1.5e-05 25.3 0.1 2.1e-05 24.8 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 CDJ97045.1 - 4.5e-05 23.5 0.2 7.7e-05 22.8 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CDJ97045.1 - 5.2e-05 23.5 0.1 9.3e-05 22.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDJ97045.1 - 0.0002 21.7 0.0 0.00021 21.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 CDJ97045.1 - 0.0027 17.7 0.0 0.0045 17.0 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 CDJ97045.1 - 0.0068 16.5 0.0 0.0076 16.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TAFII28 PF04719.14 CDJ97045.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.3 1 1 0 1 1 1 0 hTAFII28-like protein conserved region UPF0137 PF03677.13 CDJ97045.1 - 0.16 11.8 0.0 0.19 11.5 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 CDJ97046.1 - 1.7e-24 86.6 0.9 2.1e-24 86.3 0.9 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CDJ97046.1 - 9.3e-07 29.0 0.0 2.2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 CDJ97046.1 - 0.00074 19.6 0.7 0.00089 19.3 0.7 1.2 1 0 0 1 1 1 1 YscO-like protein TFIID_20kDa PF03847.13 CDJ97046.1 - 0.00082 19.8 0.0 0.0015 19.0 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 CDJ97046.1 - 0.031 14.5 0.1 0.044 14.0 0.1 1.2 1 0 0 1 1 1 0 CENP-W protein RP-C PF03428.13 CDJ97046.1 - 0.036 13.7 1.5 2.3 7.8 0.0 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain DUF1931 PF09123.11 CDJ97046.1 - 0.075 13.1 0.0 0.21 11.7 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1931) Histone PF00125.24 CDJ97047.1 - 1.7e-24 86.6 0.9 2.1e-24 86.3 0.9 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CDJ97047.1 - 9.3e-07 29.0 0.0 2.2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 CDJ97047.1 - 0.00074 19.6 0.7 0.00089 19.3 0.7 1.2 1 0 0 1 1 1 1 YscO-like protein TFIID_20kDa PF03847.13 CDJ97047.1 - 0.00082 19.8 0.0 0.0015 19.0 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 CDJ97047.1 - 0.031 14.5 0.1 0.044 14.0 0.1 1.2 1 0 0 1 1 1 0 CENP-W protein RP-C PF03428.13 CDJ97047.1 - 0.036 13.7 1.5 2.3 7.8 0.0 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain DUF1931 PF09123.11 CDJ97047.1 - 0.075 13.1 0.0 0.21 11.7 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1931) CT47 PF15623.6 CDJ97048.1 - 0.034 14.0 0.0 0.037 13.9 0.0 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 RhoGEF PF00621.20 CDJ97049.1 - 1.2e-34 120.1 1.1 2.2e-34 119.3 1.1 1.4 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.6 CDJ97049.1 - 1.3e-12 47.3 0.0 2.8e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDJ97049.1 - 2.2e-10 40.0 0.1 4.3e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDJ97049.1 - 4.4e-09 35.9 0.0 1.2e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 CDJ97049.1 - 2.5e-07 31.2 0.0 7.2e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 CDJ97049.1 - 0.00015 21.7 0.1 0.00033 20.6 0.1 1.5 1 0 0 1 1 1 1 PH domain DUF4113 PF13438.6 CDJ97049.1 - 0.037 14.1 0.9 3 8.0 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4113) PH_10 PF15411.6 CDJ97049.1 - 0.077 13.3 0.2 0.87 9.9 0.2 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain FCH PF00611.23 CDJ97049.1 - 0.13 12.6 0.0 1.3 9.3 0.1 2.5 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain zf-C2H2 PF00096.26 CDJ97050.1 - 2e-10 40.5 42.8 0.008 16.6 1.0 7.1 6 0 0 6 6 6 5 Zinc finger, C2H2 type BTB PF00651.31 CDJ97050.1 - 3.6e-06 27.2 0.1 7.2e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.6 CDJ97050.1 - 0.00024 21.7 60.4 0.07 14.0 3.1 8.0 8 0 0 8 8 8 6 C2H2-type zinc finger zf-MYST PF17772.1 CDJ97050.1 - 0.21 11.3 29.4 0.11 12.1 0.2 6.5 7 0 0 7 7 7 0 MYST family zinc finger domain zf-C2H2_11 PF16622.5 CDJ97050.1 - 0.44 10.4 50.1 0.17 11.7 0.6 7.3 7 0 0 7 7 7 0 zinc-finger C2H2-type zf-met PF12874.7 CDJ97050.1 - 7.3 7.1 31.9 1.2 9.6 1.1 6.8 6 0 0 6 6 6 0 Zinc-finger of C2H2 type FPN1 PF06963.12 CDJ97051.1 - 2.3e-69 234.1 0.9 2.7e-69 233.8 0.9 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) TLD PF07534.16 CDJ97052.1 - 6.5e-24 84.7 0.0 1e-23 84.1 0.0 1.3 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.18 CDJ97052.1 - 1.3e-13 51.2 0.2 2.7e-13 50.1 0.2 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Myb_DNA-bind_5 PF13873.6 CDJ97053.1 - 0.02 15.0 1.1 0.02 15.0 1.1 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Lipoprotein_10 PF03202.13 CDJ97053.1 - 0.11 12.9 3.1 4.7 7.6 0.2 2.9 2 2 0 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region Melibiase_2 PF16499.5 CDJ97054.1 - 2.1e-119 397.9 0.4 2.5e-119 397.7 0.4 1.0 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 CDJ97054.1 - 2.1e-07 30.9 0.0 4.8e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 CDJ97054.1 - 0.00031 19.8 0.0 0.00051 19.1 0.0 1.2 1 0 0 1 1 1 1 Melibiase Melibiase_2_C PF17450.2 CDJ97054.1 - 0.026 14.7 0.0 0.055 13.7 0.0 1.6 1 0 0 1 1 1 0 Alpha galactosidase A C-terminal beta sandwich domain Melibiase_2 PF16499.5 CDJ97055.1 - 5.9e-125 416.1 3.2 7e-125 415.9 3.2 1.1 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 CDJ97055.1 - 5e-08 32.9 0.0 1.6e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 CDJ97055.1 - 0.00015 20.8 0.0 0.00027 20.0 0.0 1.4 1 0 0 1 1 1 1 Melibiase Melibiase_2 PF16499.5 CDJ97056.1 - 5.6e-14 52.0 0.3 7.3e-14 51.6 0.3 1.1 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_2 PF16499.5 CDJ97057.1 - 4.3e-24 85.2 1.5 6e-24 84.7 1.5 1.2 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 CDJ97057.1 - 6.4e-10 39.0 0.1 1.8e-09 37.5 0.0 1.8 2 1 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Gpi16 PF04113.14 CDJ97058.1 - 4.3e-54 183.9 0.0 5.3e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component GAPES4 PF17157.4 CDJ97058.1 - 0.022 15.2 0.0 0.055 13.9 0.0 1.7 1 1 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain AMP-binding PF00501.28 CDJ97059.1 - 1.2e-84 284.4 0.0 1.4e-84 284.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ97059.1 - 6.8e-23 81.4 0.3 2.4e-22 79.7 0.5 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CDJ97059.1 - 2.9e-14 52.7 1.4 6.7e-14 51.5 1.4 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Kinesin PF00225.23 CDJ97060.1 - 5.8e-103 344.3 11.6 1.5e-69 234.4 2.9 2.5 2 1 1 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 CDJ97060.1 - 9.4e-28 97.0 0.7 1.8e-23 83.1 0.1 2.6 2 0 0 2 2 2 2 Microtubule binding THOC7 PF05615.13 CDJ97060.1 - 0.029 14.7 1.0 0.029 14.7 1.0 3.4 3 0 0 3 3 3 0 Tho complex subunit 7 Kelch_1 PF01344.25 CDJ97061.1 - 1.7e-42 142.8 12.1 2.2e-12 46.4 0.0 4.8 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 CDJ97061.1 - 4.9e-30 102.8 0.2 1.3e-07 31.7 0.0 4.1 1 1 3 4 4 4 4 Kelch motif Kelch_2 PF07646.15 CDJ97061.1 - 3.6e-20 71.1 0.9 0.00024 20.9 0.0 4.3 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 CDJ97061.1 - 2.1e-14 53.4 2.5 0.023 15.0 0.0 4.3 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_4 PF13418.6 CDJ97061.1 - 3.5e-11 42.9 2.8 0.00011 22.1 0.0 4.5 3 2 1 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ97061.1 - 8.8e-09 35.2 0.1 0.26 11.3 0.0 4.3 4 0 0 4 4 4 3 Kelch motif PQQ_2 PF13360.6 CDJ97061.1 - 0.0045 16.6 0.7 0.024 14.2 0.7 2.0 1 1 0 1 1 1 1 PQQ-like domain SAM_2 PF07647.17 CDJ97062.1 - 2.6e-05 24.2 0.1 4.8e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CDJ97062.1 - 0.0084 16.5 0.2 0.015 15.8 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RAP1 PF07218.11 CDJ97062.1 - 0.24 9.6 0.5 0.37 9.0 0.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Frag1 PF10277.9 CDJ97063.1 - 1.4e-31 109.8 16.3 1.9e-31 109.3 16.3 1.2 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Ribosomal_L16 PF00252.18 CDJ97063.1 - 4.9e-22 78.3 0.0 1.1e-21 77.2 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e zf-LYAR PF08790.11 CDJ97063.1 - 2.5e-10 40.1 8.2 6.3e-10 38.8 8.2 1.8 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger NPM1-C PF16276.5 CDJ97063.1 - 0.0041 17.0 0.1 0.011 15.7 0.1 1.6 1 0 0 1 1 1 1 Nucleophosmin C-terminal domain GCN5L1 PF06320.13 CDJ97064.1 - 6.6e-42 142.3 10.4 7.8e-42 142.0 10.4 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Erf4 PF10256.9 CDJ97064.1 - 0.013 15.6 0.5 0.28 11.3 0.2 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 7/ERF4 family Mago-bind PF09282.10 CDJ97065.1 - 2.3e-15 56.1 0.8 4.9e-15 55.1 0.8 1.6 1 0 0 1 1 1 1 Mago binding rRNA_proc-arch PF13234.6 CDJ97065.1 - 0.019 14.9 0.1 0.019 14.9 0.1 1.1 1 0 0 1 1 1 0 rRNA-processing arch domain PHD PF00628.29 CDJ97066.1 - 4.2e-06 26.6 7.8 8.7e-06 25.5 7.8 1.6 1 0 0 1 1 1 1 PHD-finger Apt1 PF10351.9 CDJ97066.1 - 0.078 11.8 5.4 0.11 11.3 4.1 1.8 2 0 0 2 2 2 0 Golgi-body localisation protein domain zf-HC5HC2H PF13771.6 CDJ97066.1 - 0.12 12.6 5.4 0.097 12.9 3.4 1.9 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-RING_2 PF13639.6 CDJ97066.1 - 0.13 12.6 7.2 0.28 11.5 7.2 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C4pol PF14260.6 CDJ97066.1 - 0.16 12.4 2.5 12 6.4 0.5 2.7 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta zf-RING-like PF08746.11 CDJ97066.1 - 0.55 10.6 3.9 0.52 10.7 2.5 1.7 2 0 0 2 2 2 0 RING-like domain Presenilin PF01080.17 CDJ97066.1 - 8.2 5.1 9.6 11 4.7 9.6 1.3 1 0 0 1 1 1 0 Presenilin Beach PF02138.18 CDJ97067.1 - 1.4e-36 126.3 0.0 3e-36 125.2 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 CDJ97067.1 - 9.6e-07 29.4 3.6 0.00063 20.5 0.1 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_2 PF13360.6 CDJ97067.1 - 0.00013 21.6 0.4 0.00024 20.8 0.4 1.4 1 0 0 1 1 1 1 PQQ-like domain ANAPC4_WD40 PF12894.7 CDJ97067.1 - 0.01 16.1 0.3 0.22 11.8 0.0 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Cut12 PF11500.8 CDJ97068.1 - 0.00081 19.4 1.2 0.00081 19.4 1.2 3.5 2 1 0 3 3 3 2 Spindle pole body formation-associated protein UPF0242 PF06785.11 CDJ97068.1 - 0.014 15.5 11.5 0.014 15.5 11.5 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CSN5_C PF18323.1 CDJ97068.1 - 6.8 7.7 9.4 2.1 9.3 1.9 3.2 2 2 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain PKcGMP_CC PF16808.5 CDJ97068.1 - 7.3 6.5 17.1 0.15 11.9 1.5 3.1 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase BACK PF07707.15 CDJ97069.1 - 1.3e-36 124.8 3.5 7e-36 122.4 1.1 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 CDJ97069.1 - 1.9e-29 102.1 0.1 3.6e-29 101.2 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain UPF0182 PF03699.13 CDJ97073.1 - 0.42 8.7 4.3 0.48 8.5 4.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) CitMHS PF03600.16 CDJ97073.1 - 0.75 8.9 5.3 0.98 8.5 5.3 1.1 1 0 0 1 1 1 0 Citrate transporter Peptidase_A24 PF01478.18 CDJ97073.1 - 7.6 7.0 10.0 27 5.2 10.0 1.8 1 1 0 1 1 1 0 Type IV leader peptidase family DUF2070 PF09843.9 CDJ97074.1 - 0.97 7.6 11.1 1.2 7.3 11.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF5641 PF18701.1 CDJ97076.1 - 1.1e-14 54.4 0.1 1.9e-14 53.6 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5641) rve PF00665.26 CDJ97076.1 - 5.8e-08 32.9 0.0 1.2e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDJ97076.1 - 0.0031 17.3 0.0 0.012 15.3 0.0 2.0 1 1 0 1 1 1 1 Integrase core domain Ribonuc_L-PSP PF01042.21 CDJ97077.1 - 1.8e-40 137.7 0.1 3.6e-40 136.8 0.1 1.5 1 0 0 1 1 1 1 Endoribonuclease L-PSP Morc6_S5 PF17942.1 CDJ97077.1 - 3.7e-24 85.4 4.5 4.1e-15 56.1 0.2 2.3 2 0 0 2 2 2 2 Morc6 ribosomal protein S5 domain 2-like zf-CW PF07496.15 CDJ97077.1 - 1.5e-11 44.1 4.2 3.3e-11 43.0 4.2 1.6 1 0 0 1 1 1 1 CW-type Zinc Finger PHD PF00628.29 CDJ97077.1 - 0.022 14.6 3.0 0.051 13.5 3.0 1.5 1 0 0 1 1 1 0 PHD-finger DUF4483 PF14825.6 CDJ97077.1 - 0.65 9.7 4.3 7 6.4 1.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4483) DUF3498 PF12004.8 CDJ97077.1 - 6.8 5.8 22.7 0.027 13.7 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3498) Kunitz_BPTI PF00014.23 CDJ97078.1 - 3.3e-25 88.1 11.1 1.7e-16 60.2 6.4 2.3 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Kunitz_BPTI PF00014.23 CDJ97079.1 - 9.9e-16 57.7 13.3 2e-15 56.8 7.7 2.9 3 0 0 3 3 3 2 Kunitz/Bovine pancreatic trypsin inhibitor domain DUF3453 PF11935.8 CDJ97080.1 - 8.1e-50 169.6 0.6 8.1e-50 169.6 0.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Symplekin_C PF12295.8 CDJ97080.1 - 2.3e-26 93.1 3.0 3.7e-26 92.3 0.0 2.8 3 0 0 3 3 3 1 Symplekin tight junction protein C terminal Auts2 PF15336.6 CDJ97080.1 - 0.34 11.0 7.4 0.65 10.1 7.4 1.4 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein dTDP_sugar_isom PF00908.17 CDJ97081.1 - 1e-46 158.7 0.0 1.1e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase RWD PF05773.22 CDJ97082.1 - 8.5e-14 51.8 0.0 1.7e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 CDJ97082.1 - 1.7e-05 25.1 13.1 7e-05 23.1 13.1 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CDJ97082.1 - 0.00028 20.7 7.3 0.0028 17.5 7.6 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ97082.1 - 0.0019 18.1 7.4 0.004 17.1 7.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDJ97082.1 - 0.003 17.6 3.4 0.003 17.6 3.4 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDJ97082.1 - 0.0073 16.1 4.6 0.0073 16.1 4.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CDJ97082.1 - 0.63 9.7 7.5 0.18 11.4 3.7 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CDJ97082.1 - 2.7 7.8 10.2 0.19 11.5 5.1 1.8 2 0 0 2 2 2 0 RING-like zinc finger zf-ANAPC11 PF12861.7 CDJ97082.1 - 2.8 8.1 5.8 10 6.2 5.8 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CDJ97082.1 - 8.2 6.4 13.3 9.3 6.2 0.6 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Tho1_MOS11_C PF18592.1 CDJ97083.1 - 6.4e-08 32.3 12.0 0.00036 20.3 0.1 5.0 4 1 1 5 5 5 4 Tho1/MOS11 C-terminal domain HeH PF12949.7 CDJ97083.1 - 1.8e-07 30.7 0.3 3.4e-07 29.8 0.3 1.5 1 0 0 1 1 1 1 HeH/LEM domain SAP PF02037.27 CDJ97083.1 - 6e-06 25.9 0.2 3.1e-05 23.6 0.2 2.4 1 0 0 1 1 1 1 SAP domain Ish1 PF10281.9 CDJ97083.1 - 0.0007 19.8 0.1 0.0026 18.0 0.1 2.1 2 0 0 2 2 2 1 Putative stress-responsive nuclear envelope protein Endonuc-dimeris PF09124.10 CDJ97083.1 - 0.076 13.2 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 T4 recombination endonuclease VII, dimerisation TLP1_add_C PF18313.1 CDJ97083.1 - 0.1 12.5 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain C5-epim_C PF06662.13 CDJ97084.1 - 3.4e-67 225.6 0.0 8.4e-67 224.3 0.0 1.7 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus XAF1_C PF18608.1 CDJ97084.1 - 0.061 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 XIAP-associated factor 1 C-terminal domain Prenyltrans PF00432.21 CDJ97084.1 - 0.11 12.3 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat Glycos_transf_2 PF00535.26 CDJ97085.1 - 2e-25 89.6 0.0 3.3e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CDJ97085.1 - 3e-17 63.0 2.0 4.9e-17 62.4 2.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 CDJ97085.1 - 4.8e-07 30.4 0.1 2.7e-05 24.8 0.0 2.5 1 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Glyco_transf_7C PF02709.14 CDJ97085.1 - 8.9e-06 25.3 0.2 2.1e-05 24.1 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CDJ97085.1 - 4e-05 23.2 0.0 7.9e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 ATP_synth_reg PF14960.6 CDJ97085.1 - 0.21 11.1 0.1 0.38 10.3 0.1 1.4 1 0 0 1 1 1 0 ATP synthase regulation Voltage_CLC PF00654.20 CDJ97086.1 - 1.3e-49 169.3 20.0 4.6e-41 141.2 7.5 2.3 1 1 1 2 2 2 2 Voltage gated chloride channel WD40 PF00400.32 CDJ97087.1 - 3.6e-11 43.4 5.0 0.0033 18.2 0.2 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ97087.1 - 2.5e-07 30.9 0.0 0.029 14.7 0.0 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Amino_oxidase PF01593.24 CDJ97088.1 - 5e-57 194.2 0.0 6.1e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ97088.1 - 3.4e-12 46.4 0.0 6.6e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CDJ97088.1 - 1.1e-07 31.4 0.0 1.8e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 CDJ97088.1 - 2e-06 27.7 0.5 3.8e-06 26.7 0.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CDJ97088.1 - 3.2e-05 23.2 0.3 5e-05 22.6 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 CDJ97088.1 - 0.00027 20.1 0.1 0.00038 19.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 CDJ97088.1 - 0.00073 18.3 0.0 0.0013 17.6 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 CDJ97088.1 - 0.00082 18.8 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CDJ97088.1 - 0.0015 18.6 0.2 0.0099 15.9 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 CDJ97088.1 - 0.0033 16.7 0.1 0.012 14.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDJ97088.1 - 0.0033 17.9 2.0 0.11 13.1 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CDJ97088.1 - 0.023 14.0 0.1 0.034 13.4 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 CDJ97088.1 - 0.07 12.2 0.2 0.22 10.5 0.0 1.9 3 0 0 3 3 3 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 CDJ97088.1 - 0.18 11.1 0.1 0.42 9.8 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 CDJ97088.1 - 0.22 10.0 0.1 0.34 9.4 0.1 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Neur_chan_LBD PF02931.23 CDJ97089.1 - 1.9e-47 161.5 0.1 2.4e-47 161.1 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ97089.1 - 2.7e-15 57.1 2.1 4.6e-15 56.3 2.1 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Serinc PF03348.15 CDJ97089.1 - 0.021 13.8 1.3 0.032 13.2 1.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4153 PF13687.6 CDJ97089.1 - 5 6.7 8.9 0.2 11.3 3.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4153) SAM_1 PF00536.30 CDJ97090.1 - 8.3e-09 35.8 0.0 1.6e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CDJ97090.1 - 0.0011 19.0 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_3 PF18016.1 CDJ97090.1 - 0.0021 17.8 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Tankyrase_bdg_C PF15327.6 CDJ97090.1 - 0.97 9.9 4.4 0.48 10.9 1.0 2.2 2 0 0 2 2 2 0 Tankyrase binding protein C terminal domain TTL PF03133.15 CDJ97091.1 - 2.5e-08 33.4 4.2 1.7e-06 27.4 0.3 2.5 2 1 1 3 3 3 2 Tubulin-tyrosine ligase family ThiF PF00899.21 CDJ97092.1 - 1.9e-28 99.5 0.0 2.7e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 ThiF family WD40 PF00400.32 CDJ97093.1 - 2.3e-05 25.1 4.2 1.4 9.9 0.0 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ97093.1 - 0.0002 21.6 0.0 1.6 9.1 0.0 3.5 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain OB_NTP_bind PF07717.16 CDJ97094.1 - 4.3e-27 94.3 0.0 9.2e-27 93.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 CDJ97094.1 - 2.8e-25 88.7 0.1 2.8e-25 88.7 0.1 3.4 3 1 0 3 3 2 1 Helicase associated domain (HA2) S1 PF00575.23 CDJ97094.1 - 8.1e-14 51.7 0.5 1.9e-13 50.5 0.5 1.7 1 0 0 1 1 1 1 S1 RNA binding domain Helicase_C PF00271.31 CDJ97094.1 - 1.9e-13 50.7 0.0 1.1e-12 48.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ97094.1 - 1.4e-05 24.9 0.2 4e-05 23.5 0.2 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDJ97094.1 - 9.3e-05 22.7 0.0 0.00031 21.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ97094.1 - 0.00051 19.8 0.2 0.0011 18.7 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ97094.1 - 0.0012 19.2 0.2 0.0028 18.0 0.2 1.6 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 CDJ97094.1 - 0.007 15.8 0.2 0.018 14.5 0.2 1.6 1 0 0 1 1 1 1 PhoH-like protein Flavi_DEAD PF07652.14 CDJ97094.1 - 0.012 15.5 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain T2SSE PF00437.20 CDJ97094.1 - 0.013 14.5 0.4 0.039 13.0 0.2 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein SRP54 PF00448.22 CDJ97094.1 - 0.1 12.2 0.1 0.28 10.8 0.1 1.8 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Tape_meas_lam_C PF09718.10 CDJ97095.1 - 0.081 13.1 1.1 0.11 12.6 1.1 1.4 1 1 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) BrkDBD PF09607.10 CDJ97096.1 - 2.5e-06 27.2 0.2 6.4e-06 25.8 0.2 1.7 1 0 0 1 1 1 1 Brinker DNA-binding domain CENP-B_N PF04218.13 CDJ97096.1 - 0.0003 20.4 0.1 0.00064 19.3 0.1 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 CDJ97096.1 - 0.0055 16.5 0.3 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 CDJ97096.1 - 0.027 14.6 0.2 0.053 13.7 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1542 PF07564.11 CDJ97096.1 - 0.028 14.5 0.9 0.091 12.9 0.2 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) HTH_Tnp_1 PF01527.20 CDJ97096.1 - 0.036 14.4 1.6 0.071 13.4 1.6 1.5 1 0 0 1 1 1 0 Transposase HTH_Tnp_IS630 PF01710.16 CDJ97096.1 - 0.054 13.5 0.8 0.097 12.7 0.8 1.4 1 0 0 1 1 1 0 Transposase UPF0183 PF03676.14 CDJ97097.1 - 1.1e-27 97.4 0.1 1.3e-27 97.1 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) SdrD_B PF17210.3 CDJ97097.1 - 0.056 13.7 0.0 0.061 13.5 0.0 1.2 1 0 0 1 1 1 0 SdrD B-like domain LRR_8 PF13855.6 CDJ97098.1 - 2e-40 136.3 52.6 3.9e-11 42.6 6.8 6.9 3 2 3 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 CDJ97098.1 - 2.5e-27 94.5 54.5 1.8e-06 28.2 5.2 8.6 4 2 4 9 9 9 9 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CDJ97098.1 - 8.2e-13 47.3 45.4 0.9 9.8 0.0 13.1 13 0 0 13 13 13 6 Leucine Rich repeat LRR_9 PF14580.6 CDJ97098.1 - 1.1e-10 41.3 12.1 0.00038 20.0 0.5 3.9 2 2 2 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 CDJ97098.1 - 4.4e-10 38.7 50.7 1 10.1 0.2 13.7 14 0 0 14 14 14 5 Leucine Rich Repeat LRR_5 PF13306.6 CDJ97098.1 - 1.3e-06 28.4 0.0 0.15 12.0 0.0 3.1 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRRCT PF01463.24 CDJ97098.1 - 0.0012 19.2 0.1 0.0097 16.4 0.0 2.7 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain LRR_12 PF18837.1 CDJ97098.1 - 0.014 15.0 0.2 0.075 12.7 0.2 2.4 1 0 0 1 1 1 0 Leucine-rich repeat UPF0183 PF03676.14 CDJ97099.1 - 1.2e-75 255.3 0.0 1.4e-75 255.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) CK_II_beta PF01214.18 CDJ97100.1 - 1.7e-79 265.9 0.0 2.1e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Myb_DNA-bind_5 PF13873.6 CDJ97101.1 - 4.4e-06 26.7 3.8 1.5e-05 24.9 3.8 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain AA_permease_2 PF13520.6 CDJ97102.1 - 6.9e-56 189.9 44.4 9.1e-56 189.5 43.8 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CDJ97102.1 - 1.3e-28 99.9 40.3 2.2e-28 99.1 40.3 1.3 1 1 0 1 1 1 1 Amino acid permease DUF3493 PF11998.8 CDJ97102.1 - 0.13 12.5 0.4 0.89 9.8 0.0 2.7 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 Glyoxalase PF00903.25 CDJ97103.1 - 2.9e-15 56.6 0.0 3.6e-11 43.4 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CDJ97103.1 - 1.2e-12 48.1 0.0 8.3e-08 32.5 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 CDJ97103.1 - 6.4e-05 23.1 0.0 0.063 13.4 0.0 3.0 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 CDJ97103.1 - 0.0076 16.4 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal FR47 PF08445.10 CDJ97104.1 - 0.00089 19.2 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Ank_2 PF12796.7 CDJ97104.1 - 0.0012 19.4 0.0 0.13 12.8 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Polyhedrin PF00738.18 CDJ97104.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Polyhedrin Ank_4 PF13637.6 CDJ97104.1 - 0.14 12.7 0.0 0.42 11.2 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Coat_F PF07875.12 CDJ97105.1 - 0.17 12.1 0.1 0.65 10.3 0.1 2.0 1 0 0 1 1 1 0 Coat F domain V-SNARE_C PF12352.8 CDJ97106.1 - 2.9e-20 72.3 3.8 2.9e-20 72.3 3.8 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CDJ97106.1 - 0.023 14.6 0.9 0.092 12.7 0.1 2.2 2 1 0 2 2 2 0 Sec20 DUF4656 PF15551.6 CDJ97106.1 - 0.027 14.0 0.7 0.035 13.6 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4656) DASH_Ask1 PF08655.10 CDJ97106.1 - 0.25 11.3 3.6 0.59 10.1 0.5 2.7 3 0 0 3 3 3 0 DASH complex subunit Ask1 CENP-Q PF13094.6 CDJ97106.1 - 1.7 8.8 7.7 2 8.6 1.3 2.1 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Pkinase PF00069.25 CDJ97107.1 - 5.7e-17 62.0 0.0 6.7e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ97107.1 - 2.5e-10 40.1 0.0 3.1e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ97107.1 - 0.014 14.2 0.0 0.037 12.8 0.0 1.6 1 1 1 2 2 2 0 Fungal protein kinase CAP PF00188.26 CDJ97109.1 - 0.0034 18.2 0.0 0.016 16.0 0.0 1.9 1 1 0 1 1 1 1 Cysteine-rich secretory protein family RVT_1 PF00078.27 CDJ97110.1 - 1.2e-14 54.3 0.0 2e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_9 PF12781.7 CDJ97110.1 - 0.0016 17.6 0.9 0.012 14.7 0.9 2.0 1 1 0 1 1 1 1 ATP-binding dynein motor region CPG4 PF15481.6 CDJ97112.1 - 8.6e-15 55.1 13.8 8.6e-15 55.1 13.8 2.1 2 0 0 2 2 2 1 Chondroitin proteoglycan 4 Tantalus PF15386.6 CDJ97112.1 - 0.074 13.2 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Drosophila Tantalus-like Dicty_spore_N PF04562.12 CDJ97112.1 - 0.36 11.6 15.2 0.67 10.7 15.2 1.4 1 0 0 1 1 1 0 Dictyostelium spore coat protein, N terminus Tetraspanin PF00335.20 CDJ97113.1 - 5.1e-08 32.9 0.9 8e-08 32.3 0.9 1.3 1 0 0 1 1 1 1 Tetraspanin family DUF3810 PF12725.7 CDJ97113.1 - 0.12 11.7 1.0 0.2 11.0 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) MARVEL PF01284.23 CDJ97113.1 - 0.13 12.2 3.7 0.044 13.8 0.8 1.7 2 0 0 2 2 2 0 Membrane-associating domain CSG2 PF16965.5 CDJ97113.1 - 0.56 9.1 4.9 0.6 9.0 2.7 1.8 2 0 0 2 2 2 0 Ceramide synthase regulator Motile_Sperm PF00635.26 CDJ97114.1 - 8.5e-29 99.6 3.7 1.8e-14 53.5 0.0 2.5 3 0 0 3 3 3 2 MSP (Major sperm protein) domain Peptidase_A17 PF05380.13 CDJ97116.1 - 6e-52 175.9 0.1 1e-51 175.2 0.1 1.4 1 0 0 1 1 1 1 Pao retrotransposon peptidase RVT_1 PF00078.27 CDJ97116.1 - 0.0015 18.1 0.1 0.0036 16.8 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDJ97116.1 - 0.027 14.5 0.1 0.07 13.2 0.1 1.7 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase CPSase_L_D2 PF02786.17 CDJ97117.1 - 1.4e-50 171.8 0.0 2.4e-50 171.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 CDJ97117.1 - 1.1e-19 70.5 0.0 2.4e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ACC_central PF08326.12 CDJ97117.1 - 6.5e-17 61.0 0.0 9.9e-17 60.4 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Dala_Dala_lig_C PF07478.13 CDJ97117.1 - 5e-06 26.2 0.0 1.3e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 CDJ97117.1 - 3.6e-05 23.9 0.1 0.00047 20.2 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl PF00364.22 CDJ97117.1 - 0.00026 20.8 0.0 0.001 18.8 0.0 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.6 CDJ97117.1 - 0.086 12.4 0.0 0.26 10.9 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain Biotin_carb_N PF00289.22 CDJ97119.1 - 9.3e-28 97.0 0.0 1.2e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain CoA_binding_2 PF13380.6 CDJ97119.1 - 0.0096 16.4 0.0 0.024 15.1 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain Exo_endo_phos_2 PF14529.6 CDJ97120.1 - 1.9e-07 30.9 0.1 5.6e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ97120.1 - 0.0032 17.0 0.0 0.0054 16.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family gag-asp_proteas PF13975.6 CDJ97121.1 - 0.0013 19.3 0.0 0.0055 17.2 0.0 2.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DivIC PF04977.15 CDJ97121.1 - 0.018 14.8 4.8 0.023 14.5 2.2 2.4 2 0 0 2 2 2 0 Septum formation initiator Asp_protease_2 PF13650.6 CDJ97121.1 - 0.044 14.4 0.0 0.16 12.6 0.0 2.0 1 0 0 1 1 1 0 Aspartyl protease SlyX PF04102.12 CDJ97121.1 - 0.1 13.2 1.1 0.71 10.5 1.1 2.5 1 0 0 1 1 1 0 SlyX RVP PF00077.20 CDJ97121.1 - 0.12 12.7 0.1 0.68 10.3 0.0 2.3 2 1 0 2 2 2 0 Retroviral aspartyl protease zf-CCHC PF00098.23 CDJ97121.1 - 0.19 11.9 9.5 15 5.9 5.1 3.6 2 1 0 2 2 2 0 Zinc knuckle IFT20 PF14931.6 CDJ97121.1 - 4.4 7.5 10.4 0.41 10.8 1.2 3.0 3 0 0 3 3 3 0 Intraflagellar transport complex B, subunit 20 TIL PF01826.17 CDJ97122.1 - 2.7e-12 46.8 15.4 2.7e-12 46.8 15.4 2.8 2 1 0 2 2 2 1 Trypsin Inhibitor like cysteine rich domain TIL PF01826.17 CDJ97123.1 - 5.5e-30 103.4 64.5 6e-12 45.6 11.7 6.0 5 1 1 6 6 6 3 Trypsin Inhibitor like cysteine rich domain Coatomer_E PF04733.14 CDJ97125.1 - 2.7e-89 299.4 7.7 3.3e-89 299.1 7.7 1.1 1 0 0 1 1 1 1 Coatomer epsilon subunit Endonuclease_NS PF01223.23 CDJ97125.1 - 3.9e-58 197.0 0.0 6.8e-58 196.1 0.0 1.4 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease TPR_19 PF14559.6 CDJ97125.1 - 3.9e-05 24.1 7.7 0.0035 17.8 1.8 3.6 2 1 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ97125.1 - 0.0069 16.6 1.0 1.1 9.6 0.2 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CDJ97125.1 - 0.015 16.1 1.4 39 5.4 0.1 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CDJ97125.1 - 0.022 14.8 3.0 0.025 14.6 1.1 2.1 2 0 0 2 2 2 0 Putative TPR-like repeat zf-C2H2_4 PF13894.6 CDJ97126.1 - 0.00053 20.6 0.6 0.00053 20.6 0.6 4.6 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDJ97126.1 - 0.005 16.8 0.1 0.005 16.8 0.1 2.8 3 0 0 3 3 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ97126.1 - 0.016 15.5 0.3 0.016 15.5 0.3 3.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 CDJ97126.1 - 0.023 14.5 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type FOXP-CC PF16159.5 CDJ97126.1 - 0.026 15.1 0.7 0.026 15.1 0.7 3.8 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-met PF12874.7 CDJ97126.1 - 0.049 14.0 2.8 0.37 11.2 0.4 3.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CDJ97126.1 - 0.058 13.9 0.6 0.058 13.9 0.6 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 CDJ97126.1 - 0.2 11.8 4.5 0.28 11.3 0.2 2.4 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_3rep PF18868.1 CDJ97126.1 - 0.5 11.0 8.3 0.33 11.6 2.0 2.8 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 CDJ97126.1 - 2.6 8.6 7.6 19 5.9 0.3 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-U1 PF06220.12 CDJ97126.1 - 5.4 6.9 8.3 32 4.4 0.2 2.8 2 0 0 2 2 2 0 U1 zinc finger zf-Di19 PF05605.12 CDJ97126.1 - 7.9 6.9 17.0 2.8 8.3 0.2 4.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Patched PF02460.18 CDJ97127.1 - 7.9e-169 563.4 12.6 1e-168 563.0 12.6 1.1 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 CDJ97127.1 - 1.1e-28 100.0 10.7 2.9e-27 95.4 5.4 3.2 2 2 1 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 CDJ97127.1 - 0.003 16.6 0.5 0.003 16.6 0.5 2.1 2 0 0 2 2 2 1 MMPL family SecD_SecF PF02355.16 CDJ97127.1 - 1.4 8.2 22.3 2.1 7.7 5.1 3.5 3 0 0 3 3 3 0 Protein export membrane protein 7tm_1 PF00001.21 CDJ97129.1 - 2.2e-65 220.6 0.7 3.3e-65 220.0 0.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ97129.1 - 2.5e-10 40.2 18.6 4.1e-09 36.2 9.0 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 CDJ97129.1 - 1.7e-06 27.6 17.2 0.0046 16.3 7.7 2.6 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Chromate_transp PF02417.15 CDJ97129.1 - 8.4e-06 26.0 0.0 5.9e-05 23.3 0.0 2.3 2 1 0 2 2 2 1 Chromate transporter 7TM_GPCR_Srx PF10328.9 CDJ97129.1 - 0.00032 20.4 10.9 0.00032 20.4 10.9 2.0 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srbc PF10316.9 CDJ97129.1 - 0.0023 17.5 8.7 0.0023 17.5 8.7 1.5 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc DUF3325 PF11804.8 CDJ97129.1 - 0.65 10.2 4.1 0.44 10.7 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3325) Harakiri PF15196.6 CDJ97129.1 - 1.2 9.7 9.0 0.6 10.6 0.5 3.0 3 0 0 3 3 3 0 Activator of apoptosis harakiri DUF2207 PF09972.9 CDJ97129.1 - 1.4 7.6 0.0 1.4 7.6 0.0 2.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Ldl_recept_a PF00057.18 CDJ97130.1 - 1.3e-05 25.3 2.3 2.3e-05 24.5 2.3 1.4 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A 7tm_1 PF00001.21 CDJ97131.1 - 9.8e-25 87.4 24.4 1.4e-24 86.9 24.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-LITAF-like PF10601.9 CDJ97131.1 - 2.2 8.6 0.0 2.2 8.6 0.0 5.2 5 3 0 5 5 5 0 LITAF-like zinc ribbon domain Trypan_PARP PF05887.11 CDJ97132.1 - 0.087 12.8 16.7 0.099 12.6 16.7 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RPN2_C PF18004.1 CDJ97132.1 - 0.19 11.6 35.8 0.23 11.4 35.8 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain TCP PF03634.13 CDJ97132.1 - 1.6 9.3 24.4 1.9 9.1 24.4 1.1 1 0 0 1 1 1 0 TCP family transcription factor GET2 PF08690.10 CDJ97132.1 - 2.2 7.8 14.1 3.1 7.4 14.1 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 FGF-BP1 PF06473.12 CDJ97132.1 - 2.6 7.8 25.1 2.5 7.9 25.1 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) MTBP_C PF14920.6 CDJ97132.1 - 3.1 7.5 18.8 3.3 7.4 18.8 1.0 1 0 0 1 1 1 0 MDM2-binding SpoIIP PF07454.11 CDJ97132.1 - 3.3 7.1 23.2 3.8 6.9 23.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF1764 PF08576.10 CDJ97132.1 - 3.3 8.6 31.5 4.1 8.3 31.5 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) RR_TM4-6 PF06459.12 CDJ97132.1 - 3.5 7.4 33.4 3.7 7.3 33.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2052 PF09747.9 CDJ97132.1 - 4 7.5 30.1 4.4 7.4 30.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CPSF100_C PF13299.6 CDJ97132.1 - 4.4 7.5 19.8 6.1 7.0 19.8 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Vfa1 PF08432.10 CDJ97132.1 - 4.5 7.6 35.7 5.2 7.4 35.7 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3537 PF12056.8 CDJ97132.1 - 4.6 5.9 6.8 5.1 5.8 6.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) RNA_pol_Rpc4 PF05132.14 CDJ97132.1 - 6.2 7.2 22.7 7.9 6.9 22.7 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 TRAP_alpha PF03896.16 CDJ97132.1 - 6.8 5.8 13.8 7.7 5.6 13.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Tim54 PF11711.8 CDJ97132.1 - 7.2 5.3 25.8 8.1 5.1 25.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DNA_pol_phi PF04931.13 CDJ97132.1 - 7.2 4.6 24.8 8.3 4.4 24.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi Paf1 PF03985.13 CDJ97132.1 - 7.3 5.5 32.6 6.9 5.6 32.6 1.0 1 0 0 1 1 1 0 Paf1 DUF5308 PF17233.2 CDJ97132.1 - 8.8 6.5 10.5 10 6.3 10.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Ground-like PF04155.18 CDJ97134.1 - 5.6e-22 78.2 0.1 8.7e-22 77.6 0.1 1.3 1 0 0 1 1 1 1 Ground-like domain WBP-1 PF11669.8 CDJ97136.1 - 0.0047 17.5 0.2 0.034 14.8 0.2 2.1 1 1 0 1 1 1 1 WW domain-binding protein 1 DNA_ligase_C PF17879.1 CDJ97137.1 - 0.19 11.8 0.0 0.25 11.4 0.0 1.1 1 0 0 1 1 1 0 DNA ligase C-terminal domain Transformer PF06495.11 CDJ97137.1 - 0.35 10.9 22.0 0.47 10.5 22.0 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein PRP38_assoc PF12871.7 CDJ97137.1 - 0.46 11.1 31.1 0.22 12.1 28.7 1.8 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term RSB_motif PF16294.5 CDJ97137.1 - 1.2 9.4 11.9 2.1 8.7 11.9 1.4 1 0 0 1 1 1 0 RNSP1-SAP18 binding (RSB) motif Dsh_C PF12316.8 CDJ97137.1 - 3.2 8.1 9.8 5.2 7.4 9.8 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF755 PF05501.11 CDJ97137.1 - 4.2 7.7 17.0 6.5 7.0 17.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) PET PF06297.14 CDJ97138.1 - 4.8e-33 113.3 0.1 9.2e-33 112.4 0.1 1.5 1 0 0 1 1 1 1 PET Domain LIM PF00412.22 CDJ97138.1 - 1.7e-31 108.2 33.8 1.7e-12 47.4 8.9 3.4 3 0 0 3 3 3 3 LIM domain Prok-RING_1 PF14446.6 CDJ97138.1 - 0.006 16.5 1.0 0.006 16.5 1.0 3.5 3 1 1 4 4 4 1 Prokaryotic RING finger family 1 Yippee-Mis18 PF03226.14 CDJ97138.1 - 1.6 9.0 19.2 0.14 12.4 6.4 2.8 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly CH PF00307.31 CDJ97139.1 - 1.1e-83 276.5 4.0 2.3e-19 69.6 0.2 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CDJ97139.1 - 8.2e-06 25.6 0.2 0.023 14.5 0.1 2.9 2 0 0 2 2 2 2 CAMSAP CH domain TM231 PF10149.9 CDJ97140.1 - 5.9e-26 91.5 1.2 7.1e-26 91.3 1.2 1.0 1 0 0 1 1 1 1 Transmembrane protein 231 Fmp27_WPPW PF10359.9 CDJ97140.1 - 0.091 11.6 0.1 0.12 11.2 0.1 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Hormone_recep PF00104.30 CDJ97141.1 - 1e-05 25.2 0.0 1.3e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DUF1759 PF03564.15 CDJ97142.1 - 1.3e-17 64.1 0.5 1.3e-16 60.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) ISG65-75 PF11727.8 CDJ97142.1 - 0.05 12.8 3.3 0.082 12.1 3.3 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF3160 PF11369.8 CDJ97142.1 - 0.055 11.9 0.8 0.087 11.3 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) Blo-t-5 PF11642.8 CDJ97142.1 - 0.11 12.5 2.4 0.19 11.7 1.8 1.7 2 0 0 2 2 2 0 Mite allergen Blo t 5 7tm_1 PF00001.21 CDJ97143.1 - 2.6e-20 72.9 0.0 2.6e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ97143.1 - 5.6e-05 22.6 2.9 7.4e-05 22.2 2.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TAS2R PF05296.13 CDJ97143.1 - 0.0014 17.8 0.7 0.0019 17.3 0.7 1.1 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) 7TM_GPCR_Srw PF10324.9 CDJ97143.1 - 0.0024 17.2 2.8 0.004 16.5 2.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 CDJ97143.1 - 0.0084 15.5 2.3 0.013 14.9 2.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv DUF2207 PF09972.9 CDJ97143.1 - 0.011 14.5 0.1 0.017 13.9 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4448 PF14610.6 CDJ97143.1 - 0.031 14.1 0.3 0.052 13.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Kunitz_BPTI PF00014.23 CDJ97144.1 - 2e-22 79.2 18.0 1.7e-13 50.6 5.7 2.7 3 0 0 3 3 3 2 Kunitz/Bovine pancreatic trypsin inhibitor domain RELT PF12606.8 CDJ97144.1 - 0.057 12.4 0.4 0.73 8.9 0.0 2.3 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 SPAN-X PF07458.12 CDJ97144.1 - 0.087 13.3 0.2 0.15 12.5 0.2 1.3 1 0 0 1 1 1 0 Sperm protein associated with nucleus, mapped to X chromosome ABC_tran PF00005.27 CDJ97145.1 - 5e-39 134.0 2.9 9.3e-26 91.0 0.0 2.9 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 CDJ97145.1 - 2.5e-13 50.5 1.1 0.0012 18.7 0.0 3.4 2 1 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDJ97145.1 - 1.2e-08 34.6 0.4 0.0052 16.2 0.0 3.5 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CDJ97145.1 - 0.0001 22.1 6.5 0.00093 19.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 CDJ97145.1 - 0.0012 18.9 1.6 0.0021 18.2 0.5 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 CDJ97145.1 - 0.0033 17.1 0.1 0.0078 15.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran_Xtn PF12848.7 CDJ97145.1 - 0.0034 17.4 17.0 0.054 13.5 16.6 2.8 2 1 1 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 CDJ97145.1 - 0.012 15.6 1.6 0.014 15.3 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 CDJ97145.1 - 0.022 15.0 0.1 0.065 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CDJ97145.1 - 0.027 14.9 0.2 0.15 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.6 CDJ97145.1 - 0.044 14.0 0.5 3.2 8.1 0.2 3.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SURF2 PF05477.11 CDJ97145.1 - 0.053 13.2 5.5 0.091 12.4 5.5 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) AAA_30 PF13604.6 CDJ97145.1 - 0.074 12.8 0.2 0.074 12.8 0.2 2.7 3 1 0 3 3 3 0 AAA domain AAA_23 PF13476.6 CDJ97145.1 - 0.089 13.3 0.0 0.089 13.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 CDJ97145.1 - 0.12 12.9 0.2 0.12 12.9 0.2 2.8 4 1 0 4 4 2 0 AAA domain AAA_22 PF13401.6 CDJ97145.1 - 0.13 12.5 1.6 0.3 11.4 0.3 2.4 2 1 0 2 2 2 0 AAA domain Colicin-DNase PF12639.7 CDJ97145.1 - 0.36 11.7 4.5 0.89 10.4 4.5 1.6 1 0 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin DUF3987 PF13148.6 CDJ97145.1 - 0.47 9.4 4.1 5.6 5.9 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) DUF87 PF01935.17 CDJ97145.1 - 0.52 10.4 0.0 0.52 10.4 0.0 2.3 3 0 0 3 3 2 0 Helicase HerA, central domain DUF1151 PF06625.11 CDJ97145.1 - 2.2 8.2 11.3 1.1 9.2 5.8 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1151) ETX_MTX2 PF03318.13 CDJ97146.1 - 2.6e-10 40.5 0.3 3.3e-10 40.2 0.3 1.1 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Aerolysin PF01117.20 CDJ97146.1 - 0.043 13.0 0.3 0.056 12.7 0.3 1.1 1 0 0 1 1 1 0 Aerolysin toxin DUF4989 PF16379.5 CDJ97146.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4989) DHHC PF01529.20 CDJ97147.1 - 1.6e-33 115.6 9.4 2.6e-33 115.0 5.4 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Oxidored_q5_N PF01059.17 CDJ97147.1 - 0.012 15.7 0.0 0.012 15.7 0.0 2.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus SH3_9 PF14604.6 CDJ97147.1 - 0.065 13.1 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Variant SH3 domain SH3_2 PF07653.17 CDJ97147.1 - 0.066 12.9 0.1 0.2 11.4 0.1 1.8 1 0 0 1 1 1 0 Variant SH3 domain MSSP PF03940.13 CDJ97147.1 - 0.1 12.2 2.8 0.19 11.3 2.8 1.4 1 0 0 1 1 1 0 Male specific sperm protein TatC PF00902.18 CDJ97147.1 - 3.3 7.5 10.6 49 3.7 10.6 2.0 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) FoP_duplication PF13865.6 CDJ97148.1 - 8.3e-09 35.9 16.3 7e-08 32.9 7.6 2.4 2 0 0 2 2 2 2 C-terminal duplication domain of Friend of PRMT1 Gal_mutarotas_3 PF18080.1 CDJ97148.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Galactose mutarotase-like fold domain Peptidase_S24 PF00717.23 CDJ97149.1 - 0.00011 22.0 0.0 0.00031 20.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase S24-like zf-CCCH_4 PF18044.1 CDJ97150.1 - 3.7e-17 61.7 32.2 5.2e-07 29.3 1.7 4.9 4 0 0 4 4 4 3 CCCH-type zinc finger zf-CCCH PF00642.24 CDJ97150.1 - 2.7e-15 55.8 32.8 3.2e-06 26.9 3.0 5.9 6 0 0 6 6 6 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CDJ97150.1 - 6.5e-12 46.1 19.2 0.00013 22.6 0.8 4.4 3 1 1 4 4 4 3 Torus domain zf_CCCH_4 PF18345.1 CDJ97150.1 - 6.8e-11 41.9 46.2 7.1e-06 25.9 7.3 6.2 6 1 0 6 6 6 3 Zinc finger domain DUF2013 PF09431.10 CDJ97150.1 - 4.9e-06 26.8 0.2 0.00012 22.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) zf-C3HC4 PF00097.25 CDJ97150.1 - 1e-05 25.3 8.3 1e-05 25.3 8.3 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ97150.1 - 6.7e-05 23.1 12.8 6.7e-05 23.1 12.8 3.8 3 0 0 3 3 2 1 Ring finger domain zf-CCCH_3 PF15663.5 CDJ97150.1 - 0.00017 21.8 2.9 0.00017 21.8 2.9 3.2 3 0 0 3 3 3 1 Zinc-finger containing family zf-RING_UBOX PF13445.6 CDJ97150.1 - 0.00046 20.2 4.7 0.00046 20.2 4.7 2.6 3 0 0 3 3 3 1 RING-type zinc-finger zf-CCCH_2 PF14608.6 CDJ97150.1 - 0.019 15.4 3.5 0.019 15.4 3.5 5.5 5 0 0 5 5 5 0 RNA-binding, Nab2-type zinc finger Proteasom_PSMB PF10508.9 CDJ97150.1 - 0.056 11.9 0.0 3.6 6.0 0.0 2.2 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit zf-RING_11 PF17123.5 CDJ97150.1 - 0.083 12.7 7.7 0.32 10.8 7.7 2.1 1 0 0 1 1 1 0 RING-like zinc finger MINDY_DUB PF04424.13 CDJ97151.1 - 2.8e-29 101.5 0.0 5.8e-29 100.5 0.0 1.6 1 0 0 1 1 1 1 MINDY deubiquitinase RRM_1 PF00076.22 CDJ97152.1 - 2.3e-16 59.3 0.0 1.7e-10 40.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Collagen PF01391.18 CDJ97153.1 - 5.2e-23 80.6 117.4 1.6e-09 37.3 42.5 4.0 2 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ97153.1 - 1.8e-19 69.5 0.5 2.4e-19 69.1 0.5 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Oleosin PF01277.17 CDJ97153.1 - 0.083 12.6 0.1 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Oleosin Ribosomal_S7 PF00177.21 CDJ97154.1 - 6.6e-06 25.8 0.0 8.5e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e CDC45 PF02724.14 CDJ97155.1 - 0.19 10.0 8.7 0.23 9.7 8.7 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 CDJ97155.1 - 0.5 10.2 6.4 0.64 9.8 6.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCDC53 PF10152.9 CDJ97155.1 - 0.57 10.6 7.0 0.8 10.1 7.0 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Gti1_Pac2 PF09729.9 CDJ97155.1 - 1.2 9.2 7.6 1.6 8.8 7.6 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Striatin PF08232.12 CDJ97155.1 - 1.4 9.5 9.4 2.1 9.0 9.4 1.3 1 0 0 1 1 1 0 Striatin family HGTP_anticodon2 PF12745.7 CDJ97155.1 - 1.5 8.3 8.6 2.1 7.8 8.6 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Neur_chan_memb PF02932.16 CDJ97155.1 - 5.1 7.1 5.1 6.8 6.7 5.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ97155.1 - 7.4 5.2 9.0 9.5 4.9 9.0 1.1 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 CDJ97155.1 - 7.6 5.4 7.5 9.2 5.2 7.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 CDJ97155.1 - 9.8 4.2 6.5 12 3.9 6.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4817 PF16087.5 CDJ97156.1 - 4.4e-05 23.2 0.2 0.24 11.2 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain (DUF4817) HTH_48 PF17906.1 CDJ97156.1 - 4.6e-05 23.4 4.5 0.15 12.2 0.4 2.7 2 0 0 2 2 2 2 HTH domain in Mos1 transposase Transposase_1 PF01359.18 CDJ97156.1 - 7.3e-05 22.5 0.1 0.00023 20.9 0.1 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_IclR PF09339.10 CDJ97156.1 - 8.9e-05 22.2 0.0 0.00023 20.9 0.0 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_26 PF13443.6 CDJ97156.1 - 0.00052 20.4 0.2 0.0022 18.4 0.0 2.1 3 0 0 3 3 1 1 Cro/C1-type HTH DNA-binding domain HTH_Tnp_ISL3 PF13542.6 CDJ97156.1 - 0.00066 19.0 0.1 0.0016 17.8 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 CENP-B_N PF04218.13 CDJ97156.1 - 0.0027 17.3 0.7 0.037 13.7 0.0 2.8 3 0 0 3 3 3 1 CENP-B N-terminal DNA-binding domain HTH_24 PF13412.6 CDJ97156.1 - 0.0045 16.5 0.1 0.0078 15.7 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MerR PF00376.23 CDJ97156.1 - 0.0059 16.3 0.1 0.0097 15.7 0.1 1.3 1 0 0 1 1 1 1 MerR family regulatory protein MarR_2 PF12802.7 CDJ97156.1 - 0.011 15.6 0.1 0.024 14.5 0.1 1.5 1 0 0 1 1 1 0 MarR family SpoIIID PF12116.8 CDJ97156.1 - 0.039 14.0 0.1 0.12 12.5 0.1 1.8 2 0 0 2 2 1 0 Stage III sporulation protein D DUF3602 PF12223.8 CDJ97156.1 - 0.04 14.5 0.5 0.44 11.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) Sigma70_r4 PF04545.16 CDJ97156.1 - 0.047 13.2 0.1 0.087 12.4 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_32 PF13565.6 CDJ97156.1 - 0.05 14.2 4.4 0.078 13.6 0.5 3.0 3 0 0 3 3 3 0 Homeodomain-like domain HTH_6 PF01418.17 CDJ97156.1 - 0.064 13.2 0.4 0.27 11.3 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family HTH_23 PF13384.6 CDJ97156.1 - 0.068 13.0 8.5 0.3 10.9 0.2 4.4 5 0 0 5 5 5 0 Homeodomain-like domain Sigma70_r4_2 PF08281.12 CDJ97156.1 - 0.084 12.6 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_28 PF13518.6 CDJ97156.1 - 0.097 12.8 0.1 0.097 12.8 0.1 3.4 5 0 0 5 5 5 0 Helix-turn-helix domain DUF2095 PF09868.9 CDJ97156.1 - 0.15 12.1 1.8 1 9.3 0.1 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2095) Sigma70_r3 PF04539.16 CDJ97156.1 - 0.15 12.1 0.3 0.67 10.1 0.5 2.0 2 0 0 2 2 1 0 Sigma-70 region 3 Bunya_G2 PF03563.13 CDJ97156.1 - 0.16 11.2 0.1 8.4 5.6 0.0 2.8 3 0 0 3 3 3 0 Bunyavirus glycoprotein G2 HTH_38 PF13936.6 CDJ97156.1 - 0.53 10.1 5.8 0.68 9.7 0.4 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain DUF746 PF05344.11 CDJ97156.1 - 0.59 10.0 3.8 30 4.5 0.1 3.3 4 0 0 4 4 3 0 Domain of Unknown Function (DUF746) RICTOR_V PF14668.6 CDJ97157.1 - 4e-19 68.6 0.2 1.2e-18 67.1 0.1 1.9 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.6 CDJ97157.1 - 3.9e-14 52.9 0.1 1.8e-13 50.8 0.1 2.2 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 CDJ97157.1 - 4.9e-07 29.5 0.3 4.5e-06 26.4 0.1 2.6 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain HEAT_2 PF13646.6 CDJ97157.1 - 0.006 16.9 0.2 0.83 10.1 0.0 2.9 2 1 0 2 2 2 1 HEAT repeats zf-C2HE PF16278.5 CDJ97157.1 - 0.021 15.3 0.0 0.06 13.8 0.0 1.8 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger HEAT PF02985.22 CDJ97157.1 - 0.079 13.3 0.7 14 6.2 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat DB PF01682.19 CDJ97158.1 - 4.6e-08 33.3 13.7 4.6e-08 33.3 13.7 2.6 2 0 0 2 2 2 1 DB module RICTOR_N PF14664.6 CDJ97159.1 - 1.8e-54 185.1 3.8 2.4e-54 184.8 3.8 1.1 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 CDJ97159.1 - 1.8e-05 24.4 0.0 1.8e-05 24.4 0.0 2.7 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain DUF1353 PF07087.11 CDJ97159.1 - 0.1 12.3 0.2 0.44 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1353) L51_S25_CI-B8 PF05047.16 CDJ97161.1 - 0.0011 18.8 0.4 0.0024 17.7 0.4 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Med10 PF09748.9 CDJ97162.1 - 1e-31 109.4 0.9 1.3e-31 109.1 0.9 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex UPF0203 PF05254.12 CDJ97163.1 - 1.4e-15 57.3 3.0 1.7e-15 57.0 3.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.10 CDJ97163.1 - 0.0002 21.3 1.0 0.18 11.8 0.1 2.2 2 0 0 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like DUF1397 PF07165.11 CDJ97163.1 - 0.00028 20.4 0.4 0.00031 20.2 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1397) UCR_hinge PF02320.16 CDJ97163.1 - 0.02 15.1 1.4 3.5 7.9 0.2 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Pet191_N PF10203.9 CDJ97163.1 - 0.055 13.8 1.6 8.4 6.8 0.2 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 CDJ97163.1 - 0.27 11.6 2.8 1.1 9.7 2.8 1.9 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) NDUF_B7 PF05676.13 CDJ97163.1 - 0.59 9.9 5.1 2.2 8.1 0.2 2.2 1 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Autophagy_act_C PF03987.15 CDJ97166.1 - 3.6e-19 69.1 0.7 6e-19 68.4 0.7 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain GST_N_2 PF13409.6 CDJ97166.1 - 0.0084 16.4 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PIGA PF08288.12 CDJ97167.1 - 7.1e-41 138.7 2.0 3.6e-40 136.4 0.1 2.4 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 CDJ97167.1 - 2.4e-27 96.0 0.1 4e-27 95.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 CDJ97167.1 - 2.7e-26 92.1 0.0 4.4e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CDJ97167.1 - 1.4e-22 80.5 0.1 2.6e-22 79.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CDJ97167.1 - 5.7e-12 46.4 0.0 1e-11 45.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 CDJ97167.1 - 5.3e-06 26.5 0.1 4e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like Sua5_yciO_yrdC PF01300.18 CDJ97168.1 - 9.8e-35 119.7 0.0 1.4e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination MBT PF02820.18 CDJ97169.1 - 1.5e-65 217.5 0.1 6.4e-20 71.3 0.0 4.3 4 0 0 4 4 4 4 mbt repeat UQ_con PF00179.26 CDJ97170.1 - 2.9e-16 59.4 0.0 6.2e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MRNIP PF15749.5 CDJ97170.1 - 0.017 15.9 3.4 0.026 15.2 3.4 1.3 1 0 0 1 1 1 0 MRN-interacting protein RWD PF05773.22 CDJ97170.1 - 0.032 14.5 0.5 0.28 11.5 0.0 2.2 2 0 0 2 2 2 0 RWD domain DUF3480 PF11979.8 CDJ97171.1 - 3.7e-79 266.2 0.0 6.6e-79 265.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) FYVE PF01363.21 CDJ97171.1 - 2e-17 63.1 12.1 5.5e-17 61.7 12.1 1.8 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CDJ97171.1 - 0.0046 17.2 7.0 0.016 15.4 7.0 1.9 1 0 0 1 1 1 1 FYVE-type zinc finger Prok-RING_2 PF14445.6 CDJ97171.1 - 0.75 10.0 8.5 1.9 8.7 8.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 GPR15L PF15854.5 CDJ97171.1 - 6.2 7.1 11.7 15 5.9 11.7 1.6 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 DUF3240 PF11582.8 CDJ97172.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3240) DUF2499 PF10693.9 CDJ97173.1 - 0.32 11.3 2.7 22 5.4 0.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2499) BRAP2 PF07576.12 CDJ97174.1 - 3.4e-31 107.4 0.2 8.5e-31 106.1 0.2 1.7 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 CDJ97174.1 - 8.7e-19 67.6 4.8 8.7e-19 67.6 4.8 2.2 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 CDJ97174.1 - 1.6e-09 37.9 6.7 1.6e-09 37.9 6.7 2.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ97174.1 - 1.8e-08 34.1 6.4 1.8e-08 34.1 6.4 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDJ97174.1 - 3.4e-06 27.2 6.3 3.4e-06 27.2 6.3 2.7 3 0 0 3 3 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDJ97174.1 - 6.4e-06 25.9 5.7 6.4e-06 25.9 5.7 2.5 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDJ97174.1 - 5.5e-05 22.8 3.1 5.5e-05 22.8 3.1 2.9 2 1 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CDJ97174.1 - 7.6e-05 22.7 1.7 7.6e-05 22.7 1.7 3.4 2 1 2 4 4 4 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDJ97174.1 - 0.00017 21.5 4.8 0.00017 21.5 4.8 3.1 3 1 1 4 4 2 1 zinc-RING finger domain zf-C3H2C3 PF17122.5 CDJ97174.1 - 0.00034 20.6 4.7 0.00034 20.6 4.7 2.4 3 0 0 3 3 1 1 Zinc-finger zf-C3HC4_3 PF13920.6 CDJ97174.1 - 0.00043 20.1 4.1 0.00043 20.1 4.1 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDJ97174.1 - 0.01 15.8 4.5 0.01 15.8 4.5 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CDJ97174.1 - 0.017 14.9 4.7 0.017 14.9 4.7 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DdrB PF12747.7 CDJ97174.1 - 0.039 13.8 0.7 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 DdrB-like protein RRM_1 PF00076.22 CDJ97174.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spc7 PF08317.11 CDJ97174.1 - 0.14 11.0 22.4 0.016 14.1 14.6 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein zf-Nse PF11789.8 CDJ97174.1 - 0.28 11.1 3.1 0.69 9.8 3.1 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit CSN5_C PF18323.1 CDJ97174.1 - 0.42 11.6 13.8 0.11 13.5 7.0 2.8 2 1 1 3 3 2 0 Cop9 signalosome subunit 5 C-terminal domain YABBY PF04690.13 CDJ97174.1 - 0.56 10.8 6.6 0.97 10.0 0.1 2.5 2 0 0 2 2 2 0 YABBY protein HSBP1 PF06825.12 CDJ97174.1 - 0.66 9.9 4.7 35 4.3 0.0 3.2 2 1 0 2 2 2 0 Heat shock factor binding protein 1 MutS_III PF05192.18 CDJ97174.1 - 0.71 10.1 3.5 1 9.6 2.3 1.8 2 0 0 2 2 2 0 MutS domain III zf-RING_6 PF14835.6 CDJ97174.1 - 1.6 8.6 10.1 0.26 11.2 6.0 1.9 1 1 1 2 2 2 0 zf-RING of BARD1-type protein ZapB PF06005.12 CDJ97174.1 - 3.8 8.0 20.9 0.42 11.1 12.4 2.8 2 0 0 2 2 2 0 Cell division protein ZapB Zn_ribbon_17 PF17120.5 CDJ97174.1 - 3.9 7.2 14.9 0.025 14.2 4.8 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type HemX PF04375.14 CDJ97174.1 - 4.2 6.6 17.4 3.6 6.8 0.5 2.3 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase OmpH PF03938.14 CDJ97174.1 - 5.2 7.4 22.8 0.54 10.6 16.1 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Tup_N PF08581.10 CDJ97174.1 - 5.4 7.4 18.7 0.64 10.4 4.8 4.1 2 1 2 4 4 4 0 Tup N-terminal zf-C3HC4_4 PF15227.6 CDJ97174.1 - 6.1 7.1 12.9 0.078 13.1 2.0 3.4 2 1 1 3 3 2 0 zinc finger of C3HC4-type, RING TerY_C PF15616.6 CDJ97174.1 - 7.9 6.6 17.3 4 7.6 1.7 2.6 1 1 1 2 2 2 0 TerY-C metal binding domain LMBR1 PF04791.16 CDJ97174.1 - 8.7 5.1 7.2 14 4.4 7.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4446 PF14584.6 CDJ97174.1 - 9.4 6.2 9.3 3.3 7.7 5.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Pkinase PF00069.25 CDJ97175.1 - 2e-47 161.8 0.0 2.3e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ97175.1 - 1.1e-20 74.1 0.0 1.3e-20 73.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ97175.1 - 0.00095 18.6 0.0 0.0011 18.3 0.0 1.2 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CDJ97175.1 - 0.0018 18.2 0.0 0.0043 17.0 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CDJ97175.1 - 0.0032 16.6 0.0 0.006 15.7 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 FTA2 PF13095.6 CDJ97175.1 - 0.0039 16.9 0.0 2.4 7.7 0.0 2.1 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 CDJ97175.1 - 0.023 14.2 0.0 0.05 13.1 0.0 1.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Ldl_recept_a PF00057.18 CDJ97176.1 - 4.2e-35 119.7 98.9 2.7e-10 40.3 4.1 6.8 8 0 0 8 8 8 5 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 CDJ97176.1 - 1e-10 41.9 0.2 0.00035 21.0 0.0 4.0 3 0 0 3 3 3 3 Low-density lipoprotein receptor repeat class B cEGF PF12662.7 CDJ97176.1 - 2.1e-06 27.6 2.8 2.1e-06 27.6 2.8 5.2 4 0 0 4 4 4 2 Complement Clr-like EGF-like DUF4051 PF13260.6 CDJ97177.1 - 0.073 12.8 0.7 0.11 12.2 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Zn-ribbon_8 PF09723.10 CDJ97177.1 - 0.08 13.1 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Zinc ribbon domain ADD_ATRX PF17981.1 CDJ97177.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.5 2 0 0 2 2 2 0 Cysteine Rich ADD domain TMEM131_like PF12371.8 CDJ97179.1 - 1.5e-16 60.4 4.0 5.3e-14 52.2 0.1 4.2 4 0 0 4 4 4 2 Transmembrane protein 131-like ASH PF15780.5 CDJ97179.1 - 1.6e-11 44.3 1.0 2.1e-05 24.7 0.0 5.3 5 0 0 5 5 5 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin SAGA-Tad1 PF12767.7 CDJ97180.1 - 9.7e-05 22.2 0.5 9.7e-05 22.2 0.5 3.9 2 1 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit Folliculin PF11704.8 CDJ97180.1 - 0.047 13.6 0.0 0.047 13.6 0.0 2.6 2 1 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport PUA_3 PF17785.1 CDJ97180.1 - 0.16 11.8 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 PUA-like domain Globin PF00042.22 CDJ97182.1 - 4.9e-07 30.3 0.0 8.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Globin SMC_N PF02463.19 CDJ97183.1 - 4.3e-70 235.6 20.7 5.4e-69 232.0 20.7 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CDJ97183.1 - 3.4e-22 78.9 0.0 1.2e-21 77.2 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CDJ97183.1 - 6e-14 52.6 4.5 2.4e-06 27.6 0.1 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CDJ97183.1 - 4.3e-05 23.2 0.0 8.3e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF4201 PF13870.6 CDJ97183.1 - 0.007 16.1 9.0 0.007 16.1 9.0 7.2 4 2 1 6 6 6 3 Domain of unknown function (DUF4201) AAA_24 PF13479.6 CDJ97183.1 - 0.028 14.1 9.5 0.16 11.7 0.7 4.0 4 0 0 4 4 4 0 AAA domain AAA_22 PF13401.6 CDJ97183.1 - 0.058 13.7 5.7 2.2 8.5 0.0 4.7 5 0 0 5 5 5 0 AAA domain ABC_tran PF00005.27 CDJ97183.1 - 0.086 13.4 0.0 0.086 13.4 0.0 6.0 5 2 0 5 5 4 0 ABC transporter DUF5631 PF18645.1 CDJ97183.1 - 0.45 10.9 2.8 1.7 9.1 0.1 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5631) MscS_porin PF12795.7 CDJ97183.1 - 2.9 7.4 69.2 0.051 13.1 2.0 5.8 6 1 0 6 6 6 0 Mechanosensitive ion channel porin domain AAA_15 PF13175.6 CDJ97183.1 - 3 7.5 51.8 0.017 14.8 19.1 4.4 1 1 1 2 2 1 0 AAA ATPase domain Hormone_recep PF00104.30 CDJ97184.1 - 4.4e-17 62.3 0.1 7.5e-17 61.6 0.1 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 CDJ97184.1 - 0.013 15.9 4.0 0.03 14.8 4.0 1.7 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) HTH_Tnp_Tc5 PF03221.16 CDJ97185.1 - 1.1e-11 44.6 0.0 2.4e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain UPF0122 PF04297.14 CDJ97185.1 - 0.028 14.7 0.1 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like Sigma70_r4 PF04545.16 CDJ97185.1 - 0.059 12.9 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 BpuJI_N PF11564.8 CDJ97185.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease BpuJI - N terminal Peptidase_S28 PF05577.12 CDJ97186.1 - 1.2e-26 93.6 1.6 5.9e-15 55.0 0.1 3.0 1 1 1 3 3 3 3 Serine carboxypeptidase S28 SusE PF14292.6 CDJ97186.1 - 0.036 14.3 0.3 0.8 10.0 0.0 2.3 2 0 0 2 2 2 0 SusE outer membrane protein HOASN PF14515.6 CDJ97186.1 - 0.17 12.3 0.0 0.3 11.5 0.0 1.3 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices Peptidase_S28 PF05577.12 CDJ97188.1 - 1.5e-80 271.2 0.1 1.7e-80 271.0 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 CDJ97188.1 - 0.015 14.8 0.1 0.027 14.0 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CDJ97188.1 - 0.029 14.0 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ97188.1 - 0.038 13.2 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MADF_DNA_bdg PF10545.9 CDJ97189.1 - 7.8e-15 55.0 8.1 1e-12 48.2 5.1 2.5 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 CDJ97189.1 - 1e-09 38.6 4.5 1e-09 38.6 4.5 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 CDJ97189.1 - 2.4e-09 37.1 4.8 0.00049 20.1 0.1 2.6 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 CDJ97189.1 - 0.0036 18.3 5.1 0.022 15.7 2.4 2.7 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain DUF573 PF04504.14 CDJ97189.1 - 0.035 14.8 0.3 0.14 12.8 0.3 2.1 1 0 0 1 1 1 0 Protein of unknown function, DUF573 FH2 PF02181.23 CDJ97190.1 - 1.7e-68 231.5 0.8 3e-68 230.6 0.8 1.4 1 0 0 1 1 1 1 Formin Homology 2 Domain DUF3361 PF11841.8 CDJ97190.1 - 0.0016 18.4 0.1 0.011 15.7 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) 7TM_GPCR_Srv PF10323.9 CDJ97191.1 - 1.3e-30 106.8 14.9 1.5e-30 106.5 14.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Sri PF10327.9 CDJ97191.1 - 0.006 15.8 9.5 0.006 15.8 9.5 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri Voltage_CLC PF00654.20 CDJ97191.1 - 0.11 11.7 4.2 0.14 11.4 4.2 1.2 1 0 0 1 1 1 0 Voltage gated chloride channel 7TM_GPCR_Srv PF10323.9 CDJ97192.1 - 5.8e-24 84.9 4.2 7.3e-24 84.6 4.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv DUF3989 PF13150.6 CDJ97192.1 - 0.052 13.3 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) DUF5317 PF17248.2 CDJ97192.1 - 1.1 9.2 7.0 1.7 8.7 2.7 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5317) Acyl_transf_3 PF01757.22 CDJ97193.1 - 2.9e-21 75.9 41.0 2.9e-21 75.9 41.0 2.0 2 0 0 2 2 2 1 Acyltransferase family DUF2085 PF09858.9 CDJ97193.1 - 0.015 15.8 0.0 0.015 15.8 0.0 3.7 3 1 0 4 4 4 0 Predicted membrane protein (DUF2085) Ferlin_C PF16165.5 CDJ97193.1 - 0.055 13.4 0.5 0.13 12.2 0.5 1.6 1 0 0 1 1 1 0 Ferlin C-terminus OppC_N PF12911.7 CDJ97193.1 - 0.085 12.8 0.1 0.085 12.8 0.1 4.2 4 1 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C Acyl_transf_3 PF01757.22 CDJ97194.1 - 8.2e-24 84.3 41.4 8.2e-24 84.3 41.4 2.1 2 0 0 2 2 2 2 Acyltransferase family TRAM_LAG1_CLN8 PF03798.16 CDJ97195.1 - 4e-18 65.9 24.2 4e-18 65.9 24.2 2.0 2 0 0 2 2 2 1 TLC domain DnaJ PF00226.31 CDJ97196.1 - 5.7e-15 55.2 0.0 1.1e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 CDJ97196.1 - 1e-10 41.2 0.0 1.6e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DUF2207 PF09972.9 CDJ97196.1 - 0.063 12.0 0.6 0.12 11.1 0.0 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) SET PF00856.28 CDJ97197.1 - 3.2e-13 50.4 0.2 1.7e-11 44.8 0.1 2.9 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 CDJ97197.1 - 0.0007 20.2 3.7 0.0025 18.4 3.7 2.0 1 0 0 1 1 1 1 Pre-SET motif DUF4537 PF15057.6 CDJ97197.1 - 0.011 15.7 0.1 0.039 14.0 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4537) Glyco_transf_88 PF16849.5 CDJ97197.1 - 0.014 14.4 0.0 0.021 13.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 88 Tudor_3 PF18115.1 CDJ97197.1 - 0.02 14.7 0.5 0.089 12.6 0.1 2.3 3 0 0 3 3 3 0 DNA repair protein Crb2 Tudor domain TCR PF03638.15 CDJ97197.1 - 5.6 7.4 14.7 11 6.4 14.7 1.5 1 0 0 1 1 1 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain UQ_con PF00179.26 CDJ97198.1 - 4.3e-25 88.0 0.0 5.1e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme I-set PF07679.16 CDJ97202.1 - 2.1e-76 252.0 0.0 1.9e-15 56.7 0.0 6.0 6 0 0 6 6 6 5 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ97202.1 - 6.1e-71 235.0 5.8 1.2e-14 54.7 0.0 6.0 6 0 0 6 6 6 5 Immunoglobulin domain Ig_2 PF13895.6 CDJ97202.1 - 1.1e-49 166.6 0.4 1.1e-11 44.9 0.0 5.5 5 1 1 6 6 6 5 Immunoglobulin domain ig PF00047.25 CDJ97202.1 - 3e-45 152.3 0.4 2.2e-09 37.3 0.0 6.4 6 0 0 6 6 6 5 Immunoglobulin domain V-set PF07686.17 CDJ97202.1 - 2.5e-16 59.8 9.7 0.0056 16.8 0.2 8.8 5 5 3 9 9 9 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDJ97202.1 - 5.6e-12 45.6 0.4 0.16 12.0 0.0 4.9 5 0 0 5 5 5 4 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 CDJ97202.1 - 1.2e-11 44.0 0.0 0.082 12.5 0.0 5.4 5 0 0 5 5 5 3 Immunoglobulin domain Ig_5 PF16681.5 CDJ97202.1 - 1.7e-10 41.2 0.0 0.82 10.1 0.0 5.7 6 0 0 6 6 6 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 CDJ97202.1 - 3.6e-10 40.0 0.0 0.71 10.2 0.0 5.7 6 0 0 6 6 6 2 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 CDJ97202.1 - 1.2e-08 34.9 0.0 0.034 14.2 0.0 5.3 4 1 1 5 5 5 2 C17orf99 Ig domain C1-set PF07654.15 CDJ97202.1 - 5.1e-08 33.2 0.1 3.3 8.2 0.0 5.5 5 2 0 5 5 5 2 Immunoglobulin C1-set domain Adeno_E3_CR1 PF02440.15 CDJ97202.1 - 8.8e-06 25.4 3.5 0.054 13.3 0.2 4.8 5 0 0 5 5 5 1 Adenovirus E3 region protein CR1 Receptor_2B4 PF11465.8 CDJ97202.1 - 9.8e-06 25.7 0.1 0.1 12.8 0.0 3.3 3 0 0 3 3 3 2 Natural killer cell receptor 2B4 Izumo-Ig PF16706.5 CDJ97202.1 - 3.4e-05 23.8 0.6 0.95 9.6 0.0 4.9 5 1 0 5 5 5 1 Izumo-like Immunoglobulin domain C2-set PF05790.15 CDJ97202.1 - 0.00019 21.6 0.0 11 6.3 0.0 5.6 6 0 0 6 6 6 1 Immunoglobulin C2-set domain LIM PF00412.22 CDJ97203.1 - 2e-25 88.8 29.5 1.5e-09 37.9 7.2 3.1 3 0 0 3 3 3 3 LIM domain Sema PF01403.19 CDJ97204.1 - 1.5e-117 393.0 0.0 1.9e-117 392.7 0.0 1.1 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 CDJ97204.1 - 9.3e-05 22.9 5.7 0.00019 21.9 5.7 1.5 1 0 0 1 1 1 1 Plexin repeat PSI_integrin PF17205.3 CDJ97204.1 - 0.14 11.9 4.4 0.29 10.9 4.4 1.5 1 0 0 1 1 1 0 Integrin plexin domain DHHC PF01529.20 CDJ97204.1 - 0.56 10.3 6.2 1.2 9.3 6.2 1.6 1 1 0 1 1 1 0 DHHC palmitoyltransferase Ank_2 PF12796.7 CDJ97207.1 - 1.2e-29 102.7 1.5 1.3e-16 60.9 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ97207.1 - 5.4e-29 100.2 5.5 9.6e-10 38.8 0.2 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ97207.1 - 5.1e-21 74.5 1.6 2.2e-11 43.8 0.1 3.5 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CDJ97207.1 - 8.6e-20 70.2 0.3 1.6e-07 31.4 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 CDJ97207.1 - 3.1e-19 67.0 0.2 5.5e-06 26.3 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat MCC-bdg_PDZ PF10506.9 CDJ97207.1 - 0.07 13.1 0.1 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Sulfotransfer_4 PF17784.1 CDJ97207.1 - 0.16 11.8 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain ETF PF01012.21 CDJ97208.1 - 1.4e-37 129.4 4.4 2.1e-37 128.8 4.4 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 CDJ97208.1 - 4.2e-37 126.1 0.9 4.2e-37 126.1 0.9 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain Ribosomal_S24e PF01282.19 CDJ97210.1 - 3.4e-24 84.6 0.1 4.3e-24 84.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S24e Ion_trans PF00520.31 CDJ97211.1 - 1.1e-11 44.4 16.3 1.9e-11 43.6 16.3 1.4 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.11 CDJ97211.1 - 0.00038 20.6 0.0 0.0009 19.4 0.0 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II ODV-E18 PF10717.9 CDJ97211.1 - 0.0069 16.2 0.1 0.029 14.2 0.1 2.0 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 ASFV_J13L PF05568.11 CDJ97211.1 - 0.12 12.1 0.6 0.3 10.8 0.1 1.9 2 0 0 2 2 2 0 African swine fever virus J13L protein CAP PF00188.26 CDJ97213.1 - 9.4e-16 58.8 4.0 1.3e-15 58.3 4.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Abhydro_lipase PF04083.16 CDJ97214.1 - 1.2e-26 92.0 0.0 4.7e-25 86.9 0.0 2.3 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 CDJ97214.1 - 2.6e-21 76.5 0.6 4.3e-21 75.7 0.6 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ97214.1 - 1.1e-06 28.1 0.0 9.4e-05 21.8 0.0 2.3 2 1 0 2 2 2 2 Serine aminopeptidase, S33 EF-hand_1 PF00036.32 CDJ97215.1 - 4.2e-40 132.3 17.8 5e-10 38.2 1.7 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ97215.1 - 1.8e-32 111.6 7.5 1.9e-15 57.1 3.3 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ97215.1 - 1.1e-31 108.4 16.9 1.7e-13 50.1 3.2 4.3 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CDJ97215.1 - 7.5e-30 100.3 6.5 9.3e-10 37.7 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CDJ97215.1 - 4.1e-24 83.0 8.4 3.6e-06 26.2 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CDJ97215.1 - 1.5e-13 50.9 0.2 2.7e-06 27.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CDJ97215.1 - 3.8e-09 36.4 2.6 0.0011 18.8 0.1 2.9 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CDJ97215.1 - 2.5e-07 31.0 0.6 0.014 15.7 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CDJ97215.1 - 6.6e-05 23.7 0.1 0.029 15.3 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 CDJ97215.1 - 0.00019 21.6 1.3 0.25 11.6 0.1 3.4 1 1 1 2 2 2 1 Dockerin type I domain UPF0154 PF03672.13 CDJ97215.1 - 0.001 19.0 1.5 0.028 14.5 0.3 3.4 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) Phage_TAC_12 PF12363.8 CDJ97215.1 - 0.0046 17.4 0.1 1.3 9.5 0.0 2.4 2 0 0 2 2 2 1 Phage tail assembly chaperone protein, TAC Caleosin PF05042.13 CDJ97215.1 - 0.0048 16.8 2.6 5.3 6.9 0.0 3.6 1 1 3 4 4 4 1 Caleosin related protein EFhand_Ca_insen PF08726.10 CDJ97215.1 - 0.0051 16.9 4.7 0.0064 16.6 0.5 2.5 1 1 2 3 3 3 1 Ca2+ insensitive EF hand TerB PF05099.13 CDJ97215.1 - 0.013 15.5 1.3 1.2 9.1 0.1 2.8 1 1 1 2 2 2 0 Tellurite resistance protein TerB DUF3016 PF11454.8 CDJ97215.1 - 0.029 14.1 0.1 0.036 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) DUF1296 PF06972.11 CDJ97215.1 - 0.038 14.1 0.6 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) DUF3349 PF11829.8 CDJ97215.1 - 0.039 14.7 0.1 5.5 7.8 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) Cadherin_C PF01049.17 CDJ97215.1 - 1.7 8.9 6.3 1.3 9.3 0.4 2.1 2 0 0 2 2 2 0 Cadherin cytoplasmic region Aa_trans PF01490.18 CDJ97216.1 - 1.8e-34 119.1 24.0 1.6e-32 112.7 24.0 2.1 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CDJ97216.1 - 0.065 12.3 19.5 2.1 7.3 19.5 2.6 1 1 0 1 1 1 0 Tryptophan/tyrosine permease family DUF2663 PF10864.8 CDJ97216.1 - 5.1 7.5 5.7 6 7.3 4.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2663) PMI_typeI PF01238.21 CDJ97217.1 - 6.4e-88 295.5 0.0 8.1e-88 295.1 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I ARD PF03079.14 CDJ97217.1 - 0.0094 16.1 0.1 0.63 10.2 0.0 2.5 2 0 0 2 2 2 1 ARD/ARD' family SpoIIIAH PF12685.7 CDJ97219.1 - 0.00055 19.8 2.5 0.00068 19.5 2.5 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein DUF4820 PF16091.5 CDJ97219.1 - 0.2 11.0 3.9 0.29 10.5 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Presenilin PF01080.17 CDJ97219.1 - 0.2 10.4 3.1 0.22 10.2 3.1 1.2 1 0 0 1 1 1 0 Presenilin Sec62 PF03839.16 CDJ97219.1 - 0.46 10.0 2.8 0.62 9.5 2.8 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Zip PF02535.22 CDJ97219.1 - 0.51 9.5 2.0 0.55 9.4 2.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Serinc PF03348.15 CDJ97219.1 - 0.55 9.1 0.9 0.65 8.9 0.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DNA_pol_phi PF04931.13 CDJ97219.1 - 0.6 8.1 9.5 0.64 8.0 9.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 CDJ97219.1 - 0.7 9.5 9.6 4 7.1 9.6 2.1 1 1 0 1 1 1 0 FAM176 family Hid1 PF12722.7 CDJ97219.1 - 1.5 6.8 3.7 1.7 6.7 3.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Connexin PF00029.19 CDJ97219.1 - 3.5 7.3 3.8 5.2 6.8 3.7 1.4 1 1 0 1 1 1 0 Connexin CDC45 PF02724.14 CDJ97219.1 - 4.4 5.5 10.0 4.6 5.4 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein MAP17 PF15807.5 CDJ97219.1 - 5.5 7.2 7.1 15 5.9 7.1 1.7 1 1 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 NPR3 PF03666.13 CDJ97219.1 - 7.9 5.1 8.2 8.5 5.0 8.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 EF_TS PF00889.19 CDJ97222.1 - 1.6e-23 83.4 0.0 3.8e-23 82.2 0.0 1.6 1 1 0 1 1 1 1 Elongation factor TS CPG4 PF15481.6 CDJ97223.1 - 5.4e-05 23.7 4.2 5.4e-05 23.7 4.2 2.0 2 0 0 2 2 2 1 Chondroitin proteoglycan 4 DEAD PF00270.29 CDJ97224.1 - 2e-16 60.3 0.0 2.8e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sre PF03125.18 CDJ97225.1 - 8.5e-17 61.3 14.0 8.5e-17 61.3 14.0 1.5 1 1 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor 7TM_GPCR_Srab PF10292.9 CDJ97225.1 - 2.1e-10 40.0 8.9 7.5e-05 21.8 0.7 2.3 1 1 1 2 2 2 2 Serpentine type 7TM GPCR receptor class ab chemoreceptor MerC PF03203.14 CDJ97225.1 - 5.8 7.4 11.4 5.8 7.4 6.3 3.0 2 1 1 3 3 3 0 MerC mercury resistance protein TILa PF12714.7 CDJ97226.1 - 0.045 13.7 13.2 4.5 7.3 0.0 4.5 4 1 0 4 4 4 0 TILa domain zf-CCHC_3 PF13917.6 CDJ97226.1 - 0.26 11.3 5.6 1.3 9.1 0.1 3.0 3 0 0 3 3 3 0 Zinc knuckle VWC PF00093.18 CDJ97226.1 - 0.33 11.3 5.8 19 5.7 0.1 3.3 2 1 0 2 2 2 0 von Willebrand factor type C domain HRM PF02793.22 CDJ97226.1 - 4.1 7.8 7.4 2.5 8.4 0.1 3.2 3 1 1 4 4 4 0 Hormone receptor domain FYVE PF01363.21 CDJ97227.1 - 1.3e-18 66.9 13.3 1.3e-18 66.9 11.0 2.3 2 0 0 2 2 2 1 FYVE zinc finger TPR_MLP1_2 PF07926.12 CDJ97227.1 - 3.8e-05 23.8 26.8 3.8e-05 23.8 26.8 12.0 2 2 10 13 13 13 2 TPR/MLP1/MLP2-like protein Filament PF00038.21 CDJ97227.1 - 0.00041 20.0 52.2 0.00041 20.0 52.2 8.3 1 1 3 6 6 6 2 Intermediate filament protein zf-C2H2_9 PF16293.5 CDJ97227.1 - 0.0015 18.4 0.9 0.028 14.3 0.1 3.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (1 copy) ERM PF00769.19 CDJ97227.1 - 0.0026 17.6 26.2 0.0026 17.6 26.2 8.3 1 1 6 7 7 7 2 Ezrin/radixin/moesin family CALCOCO1 PF07888.11 CDJ97227.1 - 0.0028 16.6 53.1 0.0028 16.6 53.1 6.0 1 1 5 6 6 6 1 Calcium binding and coiled-coil domain (CALCOCO1) like zf-C2H2_4 PF13894.6 CDJ97227.1 - 0.13 13.2 0.1 0.13 13.2 0.1 3.9 2 1 1 3 3 3 0 C2H2-type zinc finger IBR PF01485.21 CDJ97227.1 - 0.31 11.3 5.9 1.2 9.5 5.9 2.0 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Titin_Ig-rpts PF06582.12 CDJ97227.1 - 4.5 7.3 8.4 54 3.8 0.1 5.1 4 0 0 4 4 4 0 Titin repeat Spc7 PF08317.11 CDJ97227.1 - 7.6 5.3 223.4 0.02 13.8 13.6 11.0 1 1 10 11 11 11 0 Spc7 kinetochore protein CUB PF00431.20 CDJ97228.1 - 2.5e-16 60.0 0.0 1.4e-09 38.2 0.0 2.1 2 0 0 2 2 2 2 CUB domain F-box-like PF12937.7 CDJ97229.1 - 0.00037 20.3 0.0 0.00095 19.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDJ97229.1 - 0.017 15.0 0.0 0.064 13.2 0.0 2.0 1 0 0 1 1 1 0 F-box domain Lectin_C PF00059.21 CDJ97230.1 - 8.7e-20 71.5 0.1 1.5e-19 70.7 0.1 1.4 1 0 0 1 1 1 1 Lectin C-type domain CUB PF00431.20 CDJ97230.1 - 6.2e-09 36.2 0.0 1.3e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 CUB domain MWFE PF15879.5 CDJ97231.1 - 1.5e-07 31.4 0.1 1.8e-07 31.2 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit EcKinase PF02958.20 CDJ97232.1 - 1.1e-08 34.7 0.2 3.7e-08 33.1 0.2 1.7 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 CDJ97232.1 - 5.9e-06 25.4 0.3 3.1e-05 23.0 0.0 1.9 1 1 0 2 2 2 1 Protein of unknown function (DUF1679) APH PF01636.23 CDJ97232.1 - 0.00076 19.5 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family CDC24_OB3 PF17244.2 CDJ97232.1 - 0.0083 15.9 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 3 Leader_CPA1 PF08252.11 CDJ97232.1 - 1.7 8.1 3.8 2.5 7.6 2.6 1.9 2 0 0 2 2 2 0 arg-2/CPA1 leader peptide NUDIX PF00293.28 CDJ97233.1 - 0.0012 18.9 0.0 0.24 11.5 0.0 2.6 2 0 0 2 2 2 2 NUDIX domain COMM_domain PF07258.14 CDJ97234.1 - 0.17 12.0 1.5 1.6 8.9 0.3 2.3 2 1 0 2 2 2 0 COMM domain zf-C2H2_4 PF13894.6 CDJ97235.1 - 0.0012 19.5 5.8 0.091 13.6 0.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CDJ97235.1 - 0.012 16.0 11.9 0.035 14.6 1.1 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-met PF12874.7 CDJ97235.1 - 0.037 14.4 0.6 0.037 14.4 0.6 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 CDJ97235.1 - 0.045 13.9 0.1 0.082 13.1 0.1 1.3 1 0 0 1 1 1 0 Aberrant zinc-finger IBR PF01485.21 CDJ97235.1 - 0.23 11.7 5.1 0.22 11.8 1.7 2.5 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 CDJ97235.1 - 2.8 8.2 5.5 1.2 9.4 2.0 2.1 2 0 0 2 2 2 0 AN1-like Zinc finger Activin_recp PF01064.23 CDJ97236.1 - 0.055 14.6 8.6 0.076 14.1 8.6 1.3 1 1 0 1 1 1 0 Activin types I and II receptor domain UPAR_LY6 PF00021.21 CDJ97236.1 - 1.1 10.0 10.8 6.1 7.6 10.8 2.0 1 1 0 1 1 1 0 u-PAR/Ly-6 domain Lectin_C PF00059.21 CDJ97237.1 - 0.0012 19.5 0.0 0.0022 18.7 0.0 1.5 1 1 0 1 1 1 1 Lectin C-type domain Ribosomal_L1 PF00687.21 CDJ97238.1 - 2.4e-32 112.3 0.0 5.6e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family LSPR PF06049.12 CDJ97238.1 - 9.5 6.5 6.0 50 4.3 0.5 3.0 2 0 0 2 2 2 0 Coagulation Factor V LSPD Repeat FBA PF04300.13 CDJ97239.1 - 2.7e-38 131.4 1.0 4.2e-37 127.5 0.0 2.3 2 0 0 2 2 2 1 F-box associated region Telomere_Sde2_2 PF13297.6 CDJ97239.1 - 1e-20 73.1 0.9 5.5e-20 70.8 0.5 2.3 2 0 0 2 2 2 1 Telomere stability C-terminal Sde2_N_Ubi PF13019.6 CDJ97239.1 - 5.6e-17 62.1 0.1 5.6e-17 62.1 0.1 2.2 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain 4HBT_3 PF13622.6 CDJ97240.1 - 4.2e-49 168.0 0.4 5.4e-49 167.7 0.4 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 CDJ97240.1 - 5.3e-25 87.8 0.3 3.7e-20 72.1 0.1 2.7 2 1 0 2 2 2 2 Acyl-CoA thioesterase Stimulus_sens_1 PF13756.6 CDJ97240.1 - 0.075 13.6 0.0 14 6.4 0.0 2.7 3 0 0 3 3 3 0 Stimulus-sensing domain Neur_chan_LBD PF02931.23 CDJ97241.1 - 1.3e-38 132.6 0.1 1.9e-38 132.1 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ97241.1 - 4.3e-32 112.1 0.0 7.5e-32 111.3 0.0 1.4 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Viral_RdRp_C PF17501.2 CDJ97241.1 - 0.046 14.2 1.4 0.046 14.2 1.4 1.9 2 0 0 2 2 2 0 Viral RNA-directed RNA polymerase MMR_HSR1 PF01926.23 CDJ97242.1 - 1.4e-16 60.6 0.1 7.1e-16 58.3 0.1 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase LMF1 PF06762.14 CDJ97242.1 - 3.4e-10 39.6 3.4 6.8e-10 38.6 3.4 1.5 1 0 0 1 1 1 1 Lipase maturation factor FeoB_N PF02421.18 CDJ97242.1 - 2.4e-08 33.7 0.1 3.9e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CDJ97242.1 - 1.6e-06 27.8 0.0 0.0005 19.7 0.0 2.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDJ97242.1 - 9.3e-05 22.4 0.3 0.13 12.1 0.1 2.8 3 0 0 3 3 3 2 RsgA GTPase Ras PF00071.22 CDJ97242.1 - 0.0003 20.4 0.1 0.014 15.0 0.0 2.9 1 1 1 2 2 2 1 Ras family Roc PF08477.13 CDJ97242.1 - 0.01 16.1 0.0 0.07 13.3 0.0 2.3 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CDJ97242.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit KH_2 PF07650.17 CDJ97242.1 - 0.017 14.9 0.3 0.037 13.9 0.3 1.5 1 0 0 1 1 1 0 KH domain Dynamin_N PF00350.23 CDJ97242.1 - 0.022 14.8 2.2 1.6 8.7 0.5 2.5 1 1 1 2 2 2 0 Dynamin family ATP_bind_1 PF03029.17 CDJ97242.1 - 0.051 13.4 0.1 0.19 11.5 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 CDJ97242.1 - 0.094 13.1 0.1 0.55 10.6 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain MnmE_helical PF12631.7 CDJ97242.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.5 1 1 0 1 1 1 0 MnmE helical domain RS4NT PF08071.12 CDJ97242.1 - 0.12 12.5 0.3 0.27 11.4 0.3 1.5 1 0 0 1 1 1 0 RS4NT (NUC023) domain RRM_5 PF13893.6 CDJ97243.1 - 8.2e-36 122.4 0.0 6.4e-32 109.8 0.0 3.1 2 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CDJ97243.1 - 2.6e-23 81.6 0.4 7.6e-07 28.9 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 CDJ97243.1 - 2.6e-09 37.2 0.0 6.7e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 RRM-like domain RRM_occluded PF16842.5 CDJ97243.1 - 0.00098 18.9 0.8 0.86 9.5 0.1 3.7 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_3 PF08777.11 CDJ97243.1 - 0.028 14.4 0.1 2.6 8.1 0.0 3.3 4 0 0 4 4 4 0 RNA binding motif DUF4523 PF15023.6 CDJ97243.1 - 0.15 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Abhydro_lipase PF04083.16 CDJ97244.1 - 1.2e-25 88.9 0.0 1.5e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region DUF3483 PF11982.8 CDJ97244.1 - 0.058 13.0 0.0 0.077 12.6 0.0 1.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3483) MFP2b PF12150.8 CDJ97245.1 - 3.2e-46 158.2 0.0 3.6e-46 158.0 0.0 1.0 1 0 0 1 1 1 1 Cytosolic motility protein Spc7 PF08317.11 CDJ97246.1 - 0.00029 19.8 79.5 0.011 14.7 10.5 4.2 1 1 3 4 4 4 3 Spc7 kinetochore protein KASH_CCD PF14662.6 CDJ97246.1 - 0.00097 19.0 20.8 0.00097 19.0 20.8 4.4 1 1 3 4 4 4 2 Coiled-coil region of CCDC155 or KASH DUF724 PF05266.14 CDJ97246.1 - 0.005 16.7 9.1 0.005 16.7 9.1 5.4 1 1 4 5 5 5 1 Protein of unknown function (DUF724) Seryl_tRNA_N PF02403.22 CDJ97246.1 - 0.027 14.7 66.8 0.16 12.2 7.0 6.3 2 2 4 6 6 6 0 Seryl-tRNA synthetase N-terminal domain DUF3584 PF12128.8 CDJ97246.1 - 3 5.2 64.4 0.78 7.2 31.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 CDJ97246.1 - 6.8 6.8 82.8 0.15 12.1 2.6 7.3 3 2 4 7 7 7 0 TPR/MLP1/MLP2-like protein DASH_Dad1 PF08649.10 CDJ97246.1 - 8.3 6.7 15.4 6.2 7.1 0.1 4.9 3 1 1 4 4 4 0 DASH complex subunit Dad1 CARD_2 PF16739.5 CDJ97247.1 - 0.0089 16.0 0.0 0.034 14.1 0.0 2.0 1 0 0 1 1 1 1 Caspase recruitment domain Laminin_G_3 PF13385.6 CDJ97247.1 - 0.018 15.2 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily vATP-synt_AC39 PF01992.16 CDJ97248.1 - 5.6e-116 387.7 2.7 6.3e-116 387.5 2.7 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Pkinase_Tyr PF07714.17 CDJ97249.1 - 7.8e-80 267.9 0.0 1.2e-79 267.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ97249.1 - 1.3e-41 142.7 0.0 2.4e-41 141.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Focal_AT PF03623.13 CDJ97249.1 - 8.2e-16 58.2 0.6 2e-15 57.0 0.6 1.6 1 0 0 1 1 1 1 Focal adhesion targeting region Kinase-like PF14531.6 CDJ97249.1 - 3e-06 26.7 0.0 2.7e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like FERM_N_2 PF18038.1 CDJ97249.1 - 6.1e-05 23.8 0.0 0.00021 22.0 0.0 2.0 1 0 0 1 1 1 1 FERM N-terminal domain FERM_N PF09379.10 CDJ97249.1 - 0.0078 16.1 0.1 1.6 8.7 0.0 3.4 3 0 0 3 3 3 1 FERM N-terminal domain Kdo PF06293.14 CDJ97249.1 - 0.021 14.2 0.1 0.043 13.2 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Translin PF01997.16 CDJ97249.1 - 0.065 13.2 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Translin family APH PF01636.23 CDJ97249.1 - 0.096 12.6 0.2 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Syntaxin_2 PF14523.6 CDJ97249.1 - 0.11 12.9 1.1 0.94 9.9 0.6 2.5 2 1 0 2 2 2 0 Syntaxin-like protein Laminin_II PF06009.12 CDJ97249.1 - 0.19 11.8 2.6 0.76 9.8 1.0 2.3 2 0 0 2 2 2 0 Laminin Domain II SET PF00856.28 CDJ97250.1 - 4e-09 37.1 0.1 1e-08 35.8 0.0 1.7 1 1 0 1 1 1 1 SET domain BNIP3 PF06553.12 CDJ97251.1 - 0.29 10.8 3.5 0.39 10.4 3.2 1.3 1 1 0 1 1 1 0 BNIP3 Abhydrolase_6 PF12697.7 CDJ97252.1 - 2.4e-26 93.7 0.0 3.2e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDJ97252.1 - 4e-16 59.4 0.0 5.5e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ97252.1 - 2.6e-08 33.4 0.0 4.6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 CDJ97252.1 - 4.7e-06 26.5 0.0 4e-05 23.4 0.0 2.0 1 1 1 2 2 2 1 PGAP1-like protein Abhydrolase_3 PF07859.13 CDJ97252.1 - 0.01 15.7 0.4 0.078 12.8 0.4 2.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 CDJ97252.1 - 0.017 14.7 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Thioesterase PF00975.20 CDJ97252.1 - 0.034 14.3 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Chlorophyllase2 PF12740.7 CDJ97252.1 - 0.036 13.0 0.1 0.064 12.2 0.1 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.25 CDJ97252.1 - 0.044 13.7 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase PF07224.11 CDJ97252.1 - 0.11 11.5 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Esterase PF00756.20 CDJ97252.1 - 0.12 12.0 0.0 0.73 9.4 0.0 2.0 2 0 0 2 2 2 0 Putative esterase DLH PF01738.18 CDJ97252.1 - 0.17 11.4 0.0 0.57 9.7 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family AXE1 PF05448.12 CDJ97252.1 - 0.2 10.3 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) F-box-like PF12937.7 CDJ97253.1 - 5.4e-09 35.8 0.2 1.7e-08 34.3 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDJ97253.1 - 5.1e-06 26.2 1.4 4.1e-05 23.3 0.3 2.6 2 0 0 2 2 2 1 F-box domain RRM_1 PF00076.22 CDJ97254.1 - 8.1e-33 112.1 0.0 2.2e-19 69.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CDJ97254.1 - 4.2e-09 36.4 0.1 0.0037 17.3 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif RRM_7 PF16367.5 CDJ97254.1 - 0.0062 16.6 0.0 0.016 15.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 CDJ97254.1 - 0.0073 16.3 0.0 0.29 11.2 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 CDJ97254.1 - 0.012 15.3 1.1 1.4 8.6 0.0 2.6 2 1 0 2 2 2 0 Histone lysine methyltransferase SET associated RRM_occluded PF16842.5 CDJ97254.1 - 0.024 14.5 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF4429 PF14472.6 CDJ97254.1 - 0.072 13.7 0.2 0.89 10.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4429) RRM_5 PF13893.6 CDJ97254.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CDJ97255.1 - 1.9e-32 110.9 0.0 6.7e-19 67.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CDJ97255.1 - 1.8e-08 34.3 0.1 0.0036 17.3 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif RRM_7 PF16367.5 CDJ97255.1 - 0.005 16.9 0.0 0.012 15.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 CDJ97255.1 - 0.0051 16.8 0.0 0.61 10.1 0.0 2.6 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 CDJ97255.1 - 0.13 11.9 0.2 25 4.6 0.2 2.7 2 1 0 2 2 2 0 Histone lysine methyltransferase SET associated RRM_1 PF00076.22 CDJ97256.1 - 1.3e-32 111.4 0.0 3e-18 65.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CDJ97256.1 - 4.7e-08 33.0 0.0 0.011 15.8 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif RRM_7 PF16367.5 CDJ97256.1 - 0.0066 16.5 0.0 0.016 15.3 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif DUF4429 PF14472.6 CDJ97256.1 - 0.092 13.3 0.1 0.92 10.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4429) GRP PF07172.11 CDJ97256.1 - 6 7.6 15.3 10 6.9 15.3 1.3 1 0 0 1 1 1 0 Glycine rich protein family RRM_1 PF00076.22 CDJ97257.1 - 2.2e-31 107.5 0.0 6.2e-18 64.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CDJ97257.1 - 2.1e-06 27.7 0.0 0.083 12.9 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif RRM_7 PF16367.5 CDJ97257.1 - 0.0033 17.5 0.0 0.01 15.9 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif B56 PF01603.20 CDJ97258.1 - 2.1e-53 181.8 0.2 2.1e-53 181.8 0.2 1.9 2 0 0 2 2 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Trypan_PARP PF05887.11 CDJ97258.1 - 0.001 19.0 2.2 0.001 19.0 2.2 1.7 2 1 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) CPSF100_C PF13299.6 CDJ97258.1 - 0.015 15.5 1.5 0.025 14.7 1.5 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Roughex PF06020.11 CDJ97258.1 - 0.088 11.9 4.0 0.12 11.4 4.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Vfa1 PF08432.10 CDJ97258.1 - 0.12 12.7 12.5 0.18 12.1 12.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sporozoite_P67 PF05642.11 CDJ97258.1 - 0.15 10.1 8.0 0.2 9.7 8.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Presenilin PF01080.17 CDJ97258.1 - 0.84 8.3 1.9 1 8.1 1.9 1.1 1 0 0 1 1 1 0 Presenilin FAM176 PF14851.6 CDJ97258.1 - 0.9 9.2 5.2 1.5 8.5 5.2 1.3 1 0 0 1 1 1 0 FAM176 family Sec62 PF03839.16 CDJ97258.1 - 0.97 8.9 5.4 1.4 8.4 5.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Tim54 PF11711.8 CDJ97258.1 - 1.2 7.9 9.3 1.7 7.4 9.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_S49_N PF08496.10 CDJ97258.1 - 1.4 8.9 6.1 3.1 7.8 6.1 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CDC45 PF02724.14 CDJ97258.1 - 1.5 7.0 5.3 1.8 6.7 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Connexin PF00029.19 CDJ97258.1 - 1.8 8.3 3.5 2.6 7.8 3.5 1.2 1 0 0 1 1 1 0 Connexin PBP_sp32 PF07222.12 CDJ97258.1 - 3.9 6.8 7.9 6.1 6.2 7.9 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Ycf1 PF05758.12 CDJ97258.1 - 5.9 4.6 8.9 3 5.6 5.1 1.9 2 0 0 2 2 2 0 Ycf1 XPG_I PF00867.18 CDJ97260.1 - 4.6e-17 62.2 0.1 1.1e-16 60.9 0.1 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CDJ97260.1 - 1.8e-16 60.5 0.0 3.9e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 CDJ97260.1 - 9e-05 22.1 0.0 0.00019 21.0 0.0 1.6 1 0 0 1 1 1 1 XPG domain containing Pkinase PF00069.25 CDJ97261.1 - 1.5e-38 132.7 0.0 2.3e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ97261.1 - 9.1e-34 116.9 0.0 1.8e-33 116.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ97261.1 - 1.9e-05 23.6 0.0 3.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase SCIMP PF15050.6 CDJ97261.1 - 0.076 13.5 0.3 0.2 12.1 0.3 1.7 1 0 0 1 1 1 0 SCIMP protein PgaD PF13994.6 CDJ97261.1 - 0.13 12.3 0.0 1.3 9.1 0.0 2.1 2 0 0 2 2 2 0 PgaD-like protein HOK_GEF PF01848.16 CDJ97261.1 - 0.56 9.7 3.1 1.5 8.3 3.1 1.8 1 0 0 1 1 1 0 Hok/gef family Activin_recp PF01064.23 CDJ97261.1 - 0.97 10.6 18.1 0.27 12.4 14.1 2.2 2 0 0 2 2 2 0 Activin types I and II receptor domain Transposase_1 PF01359.18 CDJ97262.1 - 1.9e-17 62.8 0.1 2.9e-17 62.2 0.1 1.3 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 CDJ97262.1 - 0.13 12.1 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF668 PF05003.12 CDJ97263.1 - 0.033 14.7 5.0 3.1 8.3 1.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF668) Yos9_DD PF17880.1 CDJ97263.1 - 0.066 13.3 4.1 1.1 9.3 0.7 2.2 2 0 0 2 2 2 0 Yos9 dimerzation domain FliD_N PF02465.18 CDJ97263.1 - 1 10.1 11.1 0.16 12.7 1.4 2.6 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus CoA_transf_3 PF02515.17 CDJ97263.1 - 5.9 5.9 5.6 9.1 5.3 1.1 2.0 1 1 1 2 2 2 0 CoA-transferase family III COMM_domain PF07258.14 CDJ97264.1 - 2.3e-05 24.4 0.0 6.3e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 COMM domain Methyltransf_16 PF10294.9 CDJ97265.1 - 1.3e-29 103.1 0.0 1.7e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 CDJ97265.1 - 1.1e-05 25.0 0.0 1.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 CDJ97265.1 - 0.00046 20.0 0.0 0.0006 19.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 CDJ97265.1 - 0.0032 18.1 0.0 0.006 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ97265.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain MOR2-PAG1_mid PF14228.6 CDJ97265.1 - 0.1 10.2 0.0 0.14 9.8 0.0 1.1 1 0 0 1 1 1 0 Cell morphogenesis central region PCMT PF01135.19 CDJ97265.1 - 0.12 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) JmjC PF02373.22 CDJ97266.1 - 8e-20 71.4 4.6 1.7e-19 70.3 4.6 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CDJ97266.1 - 4.5e-15 56.1 7.0 1.4e-14 54.4 7.0 1.8 1 1 0 1 1 1 1 Cupin-like domain F-box PF00646.33 CDJ97266.1 - 0.00083 19.2 0.1 0.0031 17.3 0.0 2.0 2 0 0 2 2 2 1 F-box domain DUF3557 PF12078.8 CDJ97266.1 - 0.0058 16.6 0.3 0.012 15.6 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3557) F-box-like PF12937.7 CDJ97266.1 - 0.048 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 F-box-like zf-PARP PF00645.18 CDJ97266.1 - 1.1 10.2 5.3 0.86 10.5 0.1 2.9 3 0 0 3 3 3 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-H2C2_5 PF13909.6 CDJ97267.1 - 0.00078 19.2 0.3 0.00078 19.2 0.3 3.6 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_9 PF16293.5 CDJ97267.1 - 0.0018 18.0 1.2 1.1 9.1 0.1 3.4 3 0 0 3 3 3 2 C2H2 type zinc-finger (1 copy) zf-C2H2 PF00096.26 CDJ97267.1 - 0.02 15.3 4.2 0.13 12.8 0.5 5.0 5 0 0 5 5 5 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 CDJ97267.1 - 0.031 14.9 1.3 7.4 7.3 0.0 2.9 2 0 0 2 2 2 0 FOXP coiled-coil domain DUF629 PF04780.12 CDJ97267.1 - 2.7 6.4 9.0 2.4 6.6 0.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF629) Gp-FAR-1 PF05823.12 CDJ97268.1 - 7.3e-19 68.6 0.2 9.6e-19 68.2 0.2 1.1 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) PIN_8 PF18476.1 CDJ97268.1 - 0.012 15.5 0.0 0.016 15.1 0.0 1.1 1 0 0 1 1 1 0 PIN like domain DUF1351 PF07083.11 CDJ97268.1 - 0.035 13.9 2.3 0.08 12.7 2.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1351) Baculo_PEP_C PF04513.12 CDJ97268.1 - 0.037 14.1 0.0 1.9 8.5 0.0 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Uteroglobin PF01099.17 CDJ97268.1 - 0.048 14.0 0.2 1 9.8 0.0 2.5 2 1 0 2 2 2 0 Uteroglobin family DUF2748 PF10871.8 CDJ97268.1 - 0.054 12.1 0.0 0.12 10.9 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2748) EDR1 PF14381.6 CDJ97268.1 - 0.069 12.9 0.0 0.2 11.3 0.0 1.8 1 1 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 Aminotran_5 PF00266.19 CDJ97269.1 - 3.7e-48 164.4 0.0 6.4e-48 163.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V ATP_bind_3 PF01171.20 CDJ97269.1 - 9.3e-15 54.8 0.0 2.1e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 PP-loop family Cys_Met_Meta_PP PF01053.20 CDJ97269.1 - 0.0052 15.4 0.9 0.0079 14.8 0.1 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DUF4147 PF13660.6 CDJ97269.1 - 0.11 12.0 0.2 11 5.5 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4147) Med19 PF10278.9 CDJ97270.1 - 3.6e-45 154.1 8.7 4.8e-45 153.7 8.7 1.1 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 SR-25 PF10500.9 CDJ97270.1 - 0.016 14.8 14.1 0.028 14.1 14.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Coilin_N PF15862.5 CDJ97270.1 - 2 8.3 11.3 3 7.7 11.3 1.3 1 0 0 1 1 1 0 Coilin N-terminus TMEM214 PF10151.9 CDJ97270.1 - 2.1 6.7 6.3 2.7 6.4 6.3 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator AP3D1 PF06375.11 CDJ97270.1 - 3 8.0 17.3 4.7 7.4 17.3 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Connexin PF00029.19 CDJ97270.1 - 4.2 7.1 5.3 5.8 6.6 5.3 1.1 1 0 0 1 1 1 0 Connexin DUF3464 PF11947.8 CDJ97270.1 - 5.4 6.8 8.1 8.6 6.1 8.1 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 YqfQ PF14181.6 CDJ97270.1 - 9.8 6.3 8.9 16 5.7 8.9 1.2 1 0 0 1 1 1 0 YqfQ-like protein Pkinase PF00069.25 CDJ97271.1 - 3.6e-49 167.5 0.0 5.5e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ97271.1 - 4.4e-30 104.8 0.0 7.3e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ97271.1 - 9.5e-08 31.2 0.0 5.1e-07 28.8 0.0 1.9 1 1 1 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CDJ97271.1 - 0.1 11.9 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 Kinase-like T-box PF00907.22 CDJ97272.1 - 3.4e-68 229.5 0.0 4.1e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 T-box T-box PF00907.22 CDJ97273.1 - 5.9e-64 215.7 0.1 7.3e-64 215.4 0.1 1.1 1 0 0 1 1 1 1 T-box CDV3 PF15359.6 CDJ97274.1 - 0.0078 16.7 24.2 0.0081 16.6 2.4 4.1 2 1 0 3 3 3 2 Carnitine deficiency-associated protein 3 GGACT PF06094.12 CDJ97275.1 - 7.1e-23 81.5 0.0 8.7e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 CDJ97275.1 - 0.00019 21.8 0.1 0.0003 21.1 0.1 1.3 1 0 0 1 1 1 1 AIG2-like family Ribosomal_S10 PF00338.22 CDJ97276.1 - 2.2e-18 66.3 0.0 3e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Pou PF00157.17 CDJ97276.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain DUF5559 PF17714.1 CDJ97277.1 - 0.01 15.8 1.0 0.016 15.1 0.5 1.6 1 1 0 1 1 1 1 Family of unknown function (DUF5559) Orbi_VP5 PF00901.17 CDJ97277.1 - 0.081 11.3 0.1 0.59 8.5 0.0 1.9 1 1 1 2 2 2 0 Orbivirus outer capsid protein VP5 7TM_GPCR_Srw PF10324.9 CDJ97280.1 - 7.8e-08 32.0 17.5 1.5e-07 31.1 17.3 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 CDJ97280.1 - 0.00012 21.5 15.2 0.0002 20.8 15.2 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3671 PF12420.8 CDJ97280.1 - 6.9 6.8 11.3 5 7.2 3.2 3.0 2 1 0 2 2 2 0 Protein of unknown function EB PF01683.18 CDJ97285.1 - 2.1e-17 63.2 44.0 2.6e-06 27.6 10.2 4.2 2 2 2 4 4 4 4 EB module Dickkopf_N PF04706.12 CDJ97285.1 - 0.21 12.1 29.3 3.5 8.2 1.1 4.3 3 1 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region Ras PF00071.22 CDJ97286.1 - 9e-15 54.6 0.2 1.3e-14 54.1 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ97286.1 - 1.1e-06 28.9 0.0 2.4e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 CDJ97286.1 - 0.00011 22.2 0.3 0.00017 21.5 0.3 1.4 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Arf PF00025.21 CDJ97286.1 - 0.00014 21.4 0.2 0.00017 21.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDJ97286.1 - 0.00023 20.8 0.1 0.00064 19.3 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDJ97286.1 - 0.017 15.0 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase eRF1_2 PF03464.15 CDJ97286.1 - 0.021 15.1 0.0 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 eRF1 domain 2 zf-C3HC4_2 PF13923.6 CDJ97287.1 - 3.2e-09 36.5 12.0 5.1e-09 35.8 12.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ97287.1 - 3.2e-08 33.8 11.3 5.2e-08 33.1 11.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDJ97287.1 - 5.9e-08 32.5 10.6 8.4e-08 32.0 10.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ97287.1 - 4e-07 29.8 13.0 6.4e-07 29.1 13.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ97287.1 - 8.7e-07 28.9 6.8 3.3e-06 27.0 7.0 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDJ97287.1 - 1.4e-06 28.2 12.1 2.2e-06 27.5 12.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CDJ97287.1 - 4e-06 26.9 12.9 7.6e-06 26.0 12.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CDJ97287.1 - 0.00058 19.7 8.9 0.0011 18.7 8.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CDJ97287.1 - 0.001 18.8 8.6 0.0023 17.7 8.6 1.6 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 CDJ97287.1 - 0.0037 17.4 4.7 0.0062 16.6 4.7 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 CDJ97287.1 - 0.0099 15.9 3.3 0.021 14.8 3.3 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TackOD1 PF18551.1 CDJ97287.1 - 0.019 14.7 3.6 0.032 13.9 3.6 1.3 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 zf-Nse PF11789.8 CDJ97287.1 - 0.026 14.4 3.7 0.042 13.7 3.7 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 CDJ97287.1 - 0.074 12.9 4.2 0.14 12.1 4.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 CDJ97287.1 - 0.11 12.8 10.5 0.42 10.9 10.5 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain CxC7 PF18866.1 CDJ97287.1 - 1 9.6 4.4 17 5.6 0.0 3.3 2 1 1 3 3 3 0 CxC7 like cysteine cluster associated with KDZ transposases zf-RING_11 PF17123.5 CDJ97287.1 - 4.6 7.1 10.7 12 5.8 10.7 1.8 1 0 0 1 1 1 0 RING-like zinc finger HECT PF00632.25 CDJ97289.1 - 2.5e-101 339.2 0.1 3.5e-101 338.7 0.1 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 CDJ97289.1 - 4.8e-35 119.3 8.2 3.9e-11 42.8 0.2 3.6 3 0 0 3 3 3 3 WW domain C2 PF00168.30 CDJ97289.1 - 4.9e-12 46.0 0.0 1.1e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain Phage_Gp23 PF10669.9 CDJ97289.1 - 0.056 13.8 1.8 0.11 12.8 1.8 1.5 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF4890 PF16231.5 CDJ97289.1 - 0.14 12.7 2.2 0.31 11.5 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) Ints3 PF10189.9 CDJ97290.1 - 6.9e-37 126.9 0.0 1.5e-36 125.8 0.0 1.6 1 0 0 1 1 1 1 Integrator complex subunit 3 PARM PF17061.5 CDJ97290.1 - 0.064 13.4 2.0 0.13 12.4 2.0 1.4 1 0 0 1 1 1 0 PARM PhoU PF01895.19 CDJ97290.1 - 0.47 10.9 2.9 2.3 8.7 0.1 3.1 1 1 1 2 2 2 0 PhoU domain zf-C2H2_11 PF16622.5 CDJ97291.1 - 0.071 12.9 1.6 0.18 11.6 1.6 1.7 1 0 0 1 1 1 0 zinc-finger C2H2-type PH PF00169.29 CDJ97292.1 - 1.7e-12 47.8 0.0 3e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CDJ97292.1 - 5.2e-08 33.1 0.4 1.1e-07 32.1 0.1 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 CDJ97292.1 - 3.2e-07 30.7 4.3 8.6e-06 26.1 2.3 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 CDJ97292.1 - 0.0019 18.3 0.0 0.0036 17.4 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_6 PF15406.6 CDJ97292.1 - 0.0027 18.0 0.0 0.0088 16.3 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain HEPN_LA2681 PF18733.1 CDJ97292.1 - 0.0089 15.4 0.3 0.013 14.8 0.3 1.2 1 0 0 1 1 1 1 LA2681-like HEPN RF-1 PF00472.20 CDJ97292.1 - 0.093 12.7 0.2 0.18 11.8 0.2 1.5 1 0 0 1 1 1 0 RF-1 domain Ran-binding PF05508.11 CDJ97292.1 - 0.12 11.3 2.8 0.17 10.8 2.8 1.1 1 0 0 1 1 1 0 RanGTP-binding protein ATG16 PF08614.11 CDJ97292.1 - 0.17 12.1 3.9 0.34 11.1 3.9 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Phage_GP20 PF06810.11 CDJ97292.1 - 0.28 11.0 5.7 0.27 11.0 4.9 1.4 1 1 0 1 1 1 0 Phage minor structural protein GP20 ShK PF01549.24 CDJ97293.1 - 1.3e-06 28.9 5.9 1.3e-06 28.9 5.9 4.0 5 2 0 5 5 5 2 ShK domain-like ShK PF01549.24 CDJ97294.1 - 4.9e-11 43.0 36.9 5e-06 27.0 6.0 4.6 4 2 0 4 4 4 3 ShK domain-like DUF3846 PF12957.7 CDJ97294.1 - 0.12 12.7 0.1 0.25 11.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) Ammonium_transp PF00909.21 CDJ97295.1 - 3.9e-84 282.7 15.9 4.5e-84 282.5 15.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Trehalase PF01204.18 CDJ97296.1 - 4.7e-147 490.9 2.5 5.4e-147 490.7 2.5 1.0 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 CDJ97296.1 - 0.00019 20.5 0.1 0.0025 16.8 0.2 2.2 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase SIX1_SD PF16878.5 CDJ97297.1 - 3e-42 143.6 1.6 5.9e-42 142.7 0.4 1.9 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 CDJ97297.1 - 4.8e-12 45.5 0.8 1.2e-11 44.2 0.8 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ97297.1 - 5e-10 39.1 0.3 1.3e-09 37.7 0.3 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 CDJ97297.1 - 0.061 12.8 0.0 0.2 11.2 0.0 1.9 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez MRI PF15325.6 CDJ97297.1 - 1.1 10.4 6.5 0.55 11.3 0.2 2.4 2 0 0 2 2 2 0 Modulator of retrovirus infection RPW8 PF05659.11 CDJ97298.1 - 0.017 14.8 0.5 0.026 14.2 0.5 1.2 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 FKS1_dom1 PF14288.6 CDJ97298.1 - 0.026 14.9 0.5 0.03 14.7 0.5 1.2 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Nucleoside_tran PF01733.18 CDJ97298.1 - 0.43 9.9 1.2 0.62 9.4 0.1 1.6 1 1 1 2 2 2 0 Nucleoside transporter DUF2298 PF10060.9 CDJ97299.1 - 0.0074 15.1 0.9 0.0086 14.9 0.2 1.4 2 0 0 2 2 2 1 Uncharacterized membrane protein (DUF2298) PNTB_4TM PF12769.7 CDJ97299.1 - 0.15 12.6 2.4 0.28 11.7 2.4 1.5 1 0 0 1 1 1 0 4TM region of pyridine nucleotide transhydrogenase, mitoch Claudin_2 PF13903.6 CDJ97299.1 - 0.4 10.4 5.6 13 5.5 5.6 2.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Forkhead PF00250.18 CDJ97302.1 - 9.2e-37 125.2 0.4 2.7e-36 123.7 0.4 1.9 1 0 0 1 1 1 1 Forkhead domain Mit_KHE1 PF10173.9 CDJ97302.1 - 0.099 12.7 3.5 0.22 11.6 3.5 1.5 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF4551 PF15087.6 CDJ97302.1 - 0.37 9.6 6.9 0.55 9.0 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hydin_ADK PF17213.3 CDJ97302.1 - 1.4 9.2 6.2 3.2 8.0 6.2 1.6 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Roughex PF06020.11 CDJ97302.1 - 3.8 6.5 7.3 5.9 5.9 7.3 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Lin-8 PF03353.15 CDJ97302.1 - 7.7 6.0 16.9 16 4.9 16.9 1.5 1 1 0 1 1 1 0 Ras-mediated vulval-induction antagonist NPV_P10 PF05531.12 CDJ97303.1 - 0.52 10.8 0.0 0.52 10.8 0.0 6.6 6 2 0 6 6 6 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 CDJ97303.1 - 0.58 10.8 0.1 0.58 10.8 0.1 9.0 2 1 7 10 10 10 0 SlyX DASH_Dad4 PF08650.10 CDJ97303.1 - 2.9 7.9 13.7 0.68 9.9 2.1 4.3 3 1 1 4 4 4 0 DASH complex subunit Dad4 DUF3138 PF11336.8 CDJ97303.1 - 5.8 5.4 7.1 3.7 6.1 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) OATP PF03137.20 CDJ97304.1 - 5e-129 431.1 7.7 6.3e-129 430.7 7.7 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 CDJ97304.1 - 4e-13 49.0 23.0 4.5e-11 42.3 7.1 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily Kazal_2 PF07648.15 CDJ97304.1 - 0.13 12.4 6.7 0.34 11.1 6.7 1.8 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Kunitz_BPTI PF00014.23 CDJ97305.1 - 3e-115 376.4 194.8 1.1e-16 60.7 3.4 13.5 13 0 0 13 13 13 13 Kunitz/Bovine pancreatic trypsin inhibitor domain AROS PF15684.5 CDJ97306.1 - 1.2e-06 29.1 10.3 1.2e-06 29.1 10.3 2.3 1 1 1 2 2 2 2 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 Ribosomal_S30 PF04758.14 CDJ97307.1 - 2.2e-28 98.2 11.8 3.2e-28 97.7 11.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S30 ubiquitin PF00240.23 CDJ97307.1 - 1.6e-07 31.0 0.0 3.9e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin family DltD PF04914.12 CDJ97307.1 - 0.14 11.5 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 DltD protein CAP PF00188.26 CDJ97308.1 - 4.4e-15 56.6 0.3 4.4e-15 56.6 0.3 2.1 2 0 0 2 2 2 1 Cysteine-rich secretory protein family CAP PF00188.26 CDJ97309.1 - 3.2e-15 57.1 0.3 3.2e-15 57.1 0.3 2.0 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Ground-like PF04155.18 CDJ97310.1 - 2.4e-23 82.6 2.4 4.7e-23 81.6 2.4 1.5 1 0 0 1 1 1 1 Ground-like domain DUF2219 PF09982.9 CDJ97310.1 - 0.21 10.9 0.0 4.8 6.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2219) PDZ PF00595.24 CDJ97311.1 - 3e-20 72.4 0.6 6.8e-20 71.2 0.6 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDJ97311.1 - 2.2e-10 40.2 0.0 4.3e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 CDJ97311.1 - 8.1e-10 39.2 0.1 1.8e-06 28.4 0.1 2.6 2 0 0 2 2 2 2 PH domain PH_17 PF18012.1 CDJ97311.1 - 6.9e-07 28.9 0.0 5.5e-06 26.0 0.0 2.4 2 0 0 2 2 2 1 PH domain PDZ_2 PF13180.6 CDJ97311.1 - 0.00016 21.9 0.0 0.00046 20.4 0.1 1.7 2 0 0 2 2 2 1 PDZ domain DUF19 PF01579.18 CDJ97313.1 - 2.6e-05 24.1 1.5 4.5e-05 23.3 1.5 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF19) DUF1397 PF07165.11 CDJ97313.1 - 0.0001 21.8 4.4 0.065 12.6 0.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1397) CPG4 PF15481.6 CDJ97313.1 - 0.00065 20.3 6.6 0.0022 18.6 1.8 2.8 2 1 1 3 3 3 1 Chondroitin proteoglycan 4 RGM_N PF06535.12 CDJ97313.1 - 0.14 12.4 2.0 3.4 7.8 0.1 2.3 2 0 0 2 2 2 0 Repulsive guidance molecule (RGM) N-terminus Ribosomal_S28e PF01200.18 CDJ97314.1 - 3.2e-34 116.7 1.0 3.5e-34 116.6 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e WD40 PF00400.32 CDJ97315.1 - 1.7e-21 76.1 33.0 0.0021 18.8 0.3 10.5 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ97315.1 - 3.7e-12 46.4 8.3 0.65 10.3 0.0 7.7 6 1 2 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 CDJ97315.1 - 0.002 17.5 0.1 0.26 10.5 0.0 2.7 3 0 0 3 3 3 2 CPSF A subunit region POB3_N PF17292.2 CDJ97316.1 - 2.1e-26 92.2 1.0 8.3e-23 80.6 0.3 2.5 2 0 0 2 2 2 2 POB3-like N-terminal PH domain Rtt106 PF08512.12 CDJ97316.1 - 3.8e-25 88.1 0.1 5.1e-24 84.5 0.0 2.7 2 1 0 2 2 2 1 Histone chaperone Rttp106-like SSrecog PF03531.14 CDJ97316.1 - 3.5e-22 78.1 0.0 1.6e-21 75.9 0.0 2.3 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) HMG_box PF00505.19 CDJ97316.1 - 7.6e-17 61.5 7.4 7.6e-17 61.5 7.4 2.4 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ97316.1 - 4e-11 43.3 8.3 4e-11 43.3 8.3 2.4 2 0 0 2 2 2 1 HMG-box domain HMG_box_5 PF14887.6 CDJ97316.1 - 4.3e-05 23.4 7.8 0.00013 21.8 7.8 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box 5 CD36 PF01130.21 CDJ97317.1 - 1.7e-108 363.2 0.2 2.1e-108 362.8 0.2 1.0 1 0 0 1 1 1 1 CD36 family CIAPIN1 PF05093.13 CDJ97318.1 - 1.7e-22 79.8 15.5 3e-16 59.8 3.5 2.5 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF1115 PF06544.12 CDJ97318.1 - 4.1e-11 43.2 0.0 7.9e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RWD PF05773.22 CDJ97318.1 - 1.5e-06 28.5 0.0 3.5e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 RWD domain DUF2190 PF09956.9 CDJ97318.1 - 0.0026 18.2 0.8 0.0042 17.5 0.8 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2190) NDUF_B4 PF07225.12 CDJ97320.1 - 4.1e-34 117.1 0.2 4.7e-34 116.9 0.2 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) TPR_8 PF13181.6 CDJ97321.1 - 0.00027 20.9 0.8 0.00027 20.9 0.8 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ97321.1 - 0.00041 20.9 0.2 0.76 10.5 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ97321.1 - 0.0021 18.0 2.2 0.0052 16.8 0.6 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ97321.1 - 0.0037 17.0 0.8 0.0093 15.8 0.8 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ97321.1 - 0.0055 17.4 1.6 0.076 13.9 0.1 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat YfdX PF10938.8 CDJ97321.1 - 0.01 15.7 1.0 0.21 11.5 0.1 2.1 2 0 0 2 2 2 0 YfdX protein TPR_6 PF13174.6 CDJ97321.1 - 0.017 15.7 0.7 0.73 10.6 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ97321.1 - 0.03 14.0 0.1 0.073 12.8 0.0 1.8 2 0 0 2 2 2 0 TPR repeat TPR_10 PF13374.6 CDJ97321.1 - 0.043 13.7 0.1 1.6 8.7 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4919 PF16266.5 CDJ97321.1 - 0.084 12.8 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) 7tm_1 PF00001.21 CDJ97322.1 - 1.6e-48 165.3 24.5 2.4e-48 164.8 24.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ97322.1 - 1.3e-11 44.4 24.4 1.8e-11 43.9 24.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 CDJ97322.1 - 0.004 16.8 21.6 0.004 16.8 21.6 2.4 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 CDJ97322.1 - 0.066 12.9 17.3 0.09 12.5 13.2 2.5 2 1 0 2 2 2 0 Olfactory receptor HTH_50 PF18024.1 CDJ97323.1 - 0.0017 17.9 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Neur_chan_LBD PF02931.23 CDJ97324.1 - 9.5e-47 159.2 0.4 1.5e-46 158.6 0.4 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ97324.1 - 1.9e-05 24.8 0.6 3.2e-05 24.1 0.6 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF4474 PF14751.6 CDJ97325.1 - 0.02 14.3 0.1 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4474) DLIC PF05783.11 CDJ97328.1 - 1.2e-10 40.9 0.0 4.5e-10 39.0 0.0 1.7 1 1 1 2 2 2 1 Dynein light intermediate chain (DLIC) AAA_22 PF13401.6 CDJ97328.1 - 4.1e-06 27.1 0.0 3.5e-05 24.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain Roc PF08477.13 CDJ97328.1 - 7.7e-06 26.1 0.0 3.8e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 CDJ97328.1 - 0.00012 21.6 0.0 0.00045 19.7 0.0 1.9 2 0 0 2 2 2 1 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 CDJ97328.1 - 0.00013 21.4 0.0 0.00027 20.4 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.6 CDJ97328.1 - 0.0014 19.0 0.2 0.0048 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain G-alpha PF00503.20 CDJ97328.1 - 0.0025 17.1 0.1 0.0049 16.1 0.1 1.4 1 0 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 CDJ97328.1 - 0.0049 16.3 0.0 0.0096 15.4 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CDJ97328.1 - 0.005 16.5 0.0 0.047 13.3 0.0 2.1 2 0 0 2 2 2 1 Ras family ATPase_2 PF01637.18 CDJ97328.1 - 0.0085 16.0 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 CDJ97328.1 - 0.012 15.5 0.0 0.032 14.1 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 CDJ97328.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CDJ97328.1 - 0.021 14.9 0.1 0.046 13.8 0.1 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 CDJ97328.1 - 0.022 15.1 0.0 0.091 13.2 0.0 2.0 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 CDJ97328.1 - 0.029 14.3 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 NTPase ATPase PF06745.13 CDJ97328.1 - 0.032 13.6 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 KaiC Septin PF00735.18 CDJ97328.1 - 0.035 13.4 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 Septin ABC_tran PF00005.27 CDJ97328.1 - 0.043 14.3 0.0 0.086 13.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 CDJ97328.1 - 0.062 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CDJ97328.1 - 0.063 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 CDJ97328.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Elongin_A PF06881.11 CDJ97328.1 - 0.42 11.2 3.8 0.74 10.4 0.2 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Denso_VP4 PF02336.15 CDJ97329.1 - 0.03 13.2 0.1 0.031 13.2 0.1 1.0 1 0 0 1 1 1 0 Capsid protein VP4 Asp PF00026.23 CDJ97331.1 - 2.8e-45 155.1 0.0 3.7e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ97331.1 - 1.9e-10 41.2 0.0 0.00024 21.4 0.0 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal DUF2417 PF10329.9 CDJ97332.1 - 0.0081 15.6 0.7 0.0081 15.6 0.7 1.6 2 0 0 2 2 2 1 Region of unknown function (DUF2417) RR_TM4-6 PF06459.12 CDJ97332.1 - 4.9 6.9 7.6 1 9.1 3.7 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4614 PF15391.6 CDJ97332.1 - 9.7 6.1 12.1 20 5.1 12.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Phosphodiest PF01663.22 CDJ97337.1 - 2.3e-29 103.1 0.6 2.6e-29 102.9 0.6 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sigma_reg_N PF13800.6 CDJ97337.1 - 0.0068 16.7 0.6 0.014 15.7 0.6 1.5 1 0 0 1 1 1 1 Sigma factor regulator N-terminal Phosphoesterase PF04185.14 CDJ97337.1 - 0.0082 15.4 0.2 0.01 15.0 0.2 1.1 1 0 0 1 1 1 1 Phosphoesterase family TMEM154 PF15102.6 CDJ97337.1 - 0.042 13.7 0.3 0.065 13.1 0.3 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF1218 PF06749.12 CDJ97337.1 - 0.071 13.6 0.7 0.15 12.6 0.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1218) DUF975 PF06161.11 CDJ97337.1 - 0.074 12.8 2.7 0.1 12.3 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF975) VWA PF00092.28 CDJ97338.1 - 2.3e-20 73.6 0.0 3.1e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Lectin_C PF00059.21 CDJ97338.1 - 2.9e-15 56.9 1.2 5.8e-15 56.0 1.2 1.5 1 0 0 1 1 1 1 Lectin C-type domain VWA_2 PF13519.6 CDJ97338.1 - 4.8e-11 43.3 0.1 8.3e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Sec23_trunk PF04811.15 CDJ97338.1 - 0.054 13.1 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain DuoxA PF10204.9 CDJ97339.1 - 2.3e-72 243.3 6.9 2.7e-72 243.1 6.9 1.0 1 0 0 1 1 1 1 Dual oxidase maturation factor Peptidase_M10 PF00413.24 CDJ97340.1 - 7.7e-46 155.8 0.0 1.2e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Matrixin Astacin PF01400.24 CDJ97340.1 - 0.0066 16.1 0.0 0.72 9.4 0.0 2.2 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 CDJ97340.1 - 0.0088 16.6 0.2 0.016 15.7 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 CDJ97340.1 - 0.015 15.3 0.0 0.043 13.8 0.0 1.7 2 0 0 2 2 2 0 Peptidase family M54 Reprolysin_4 PF13583.6 CDJ97340.1 - 0.017 14.7 0.1 0.035 13.7 0.0 1.5 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 CDJ97340.1 - 0.057 12.0 0.0 0.087 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_5 PF13688.6 CDJ97340.1 - 0.067 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF4953 PF16313.5 CDJ97340.1 - 0.12 11.5 0.3 0.23 10.6 0.3 1.3 1 0 0 1 1 1 0 Met-zincin DUF4899 PF16240.5 CDJ97340.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4899) PEPCK_GTP PF00821.18 CDJ97342.1 - 1.2e-163 544.0 0.1 1.6e-163 543.7 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 CDJ97342.1 - 4.2e-93 311.0 0.0 5.5e-93 310.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain MRP-L28 PF09812.9 CDJ97343.1 - 5.3e-49 166.5 8.7 6e-49 166.3 8.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 GCN5L1 PF06320.13 CDJ97343.1 - 0.78 9.9 7.6 7.6 6.7 1.0 2.5 1 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) DUF365 PF04033.12 CDJ97343.1 - 9 6.6 7.5 0.52 10.6 0.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF365) DUF1644 PF07800.12 CDJ97344.1 - 0.0058 16.7 0.4 1.4 9.0 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1644) Thyroglobulin_1 PF00086.18 CDJ97344.1 - 0.0095 15.6 1.5 0.038 13.7 1.5 2.0 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat zf-C2H2 PF00096.26 CDJ97344.1 - 0.097 13.2 28.4 0.8 10.3 0.5 5.6 5 0 0 5 5 5 0 Zinc finger, C2H2 type Spt4 PF06093.13 CDJ97345.1 - 5.5e-31 106.5 2.2 6.7e-31 106.2 2.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Pkinase_Tyr PF07714.17 CDJ97346.1 - 3.4e-34 118.3 0.0 4.9e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 CDJ97346.1 - 1.2e-27 96.3 4.4 4.3e-15 56.1 0.3 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ97346.1 - 1.4e-21 76.3 6.9 5.8e-09 36.1 1.2 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Pkinase PF00069.25 CDJ97346.1 - 1.7e-20 73.5 0.0 3.7e-20 72.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.6 CDJ97346.1 - 2e-20 72.9 1.1 2.3e-09 37.6 0.2 3.9 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 CDJ97346.1 - 1.2e-16 60.3 1.4 1.1e-05 25.6 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 CDJ97346.1 - 9.4e-14 50.2 0.6 0.0067 16.8 0.0 4.2 3 0 0 3 3 3 3 Ankyrin repeat IP_trans PF02121.18 CDJ97347.1 - 4.8e-112 373.5 0.0 5.4e-112 373.3 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein AAA_30 PF13604.6 CDJ97348.1 - 0.00023 21.0 0.3 0.00028 20.7 0.3 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CDJ97348.1 - 0.0019 18.2 0.0 0.0025 17.9 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ97348.1 - 0.0041 16.9 0.1 0.007 16.2 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 CDJ97348.1 - 0.0085 15.6 0.1 0.0095 15.5 0.1 1.1 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 CDJ97348.1 - 0.0095 15.8 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Helicase AAA_19 PF13245.6 CDJ97348.1 - 0.023 15.1 0.2 0.029 14.7 0.2 1.2 1 0 0 1 1 1 0 AAA domain PDT PF00800.18 CDJ97348.1 - 0.037 13.8 0.1 0.057 13.2 0.1 1.2 1 0 0 1 1 1 0 Prephenate dehydratase AAA_11 PF13086.6 CDJ97348.1 - 0.052 13.3 0.0 0.068 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_12 PF13087.6 CDJ97348.1 - 0.081 12.5 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain N1221 PF07923.13 CDJ97349.1 - 2.4e-11 43.3 0.0 3.1e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein V_ATPase_I PF01496.19 CDJ97350.1 - 0.11 10.5 0.1 0.12 10.3 0.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 CDJ97350.1 - 0.34 9.6 2.3 0.39 9.4 2.3 1.1 1 0 0 1 1 1 0 Presenilin Plasmodium_Vir PF05795.11 CDJ97350.1 - 0.92 8.9 5.2 1.1 8.5 5.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Na_trans_assoc PF06512.13 CDJ97350.1 - 0.98 9.7 8.7 1.1 9.6 8.7 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Raftlin PF15250.6 CDJ97350.1 - 1.8 7.2 5.5 1.9 7.1 5.5 1.0 1 0 0 1 1 1 0 Raftlin DUF2201_N PF13203.6 CDJ97350.1 - 3 7.3 6.7 3.9 7.0 6.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Pes-10 PF07149.11 CDJ97350.1 - 9.6 5.1 8.1 11 4.9 8.1 1.1 1 0 0 1 1 1 0 Pes-10 DOMON PF03351.17 CDJ97351.1 - 7.9e-49 165.0 11.3 3.5e-16 59.5 0.4 4.2 4 0 0 4 4 4 4 DOMON domain Cytochrom_B561 PF03188.16 CDJ97351.1 - 6.1e-08 32.9 6.4 1.5e-07 31.7 6.4 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 CDJ97351.1 - 0.0034 17.1 1.9 0.0091 15.8 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) MecA PF05389.12 CDJ97351.1 - 0.0057 16.3 0.1 2 8.0 0.0 2.3 2 0 0 2 2 2 2 Negative regulator of genetic competence (MecA) CSS-motif PF12792.7 CDJ97351.1 - 0.11 12.0 1.3 0.88 9.0 0.0 2.8 3 0 0 3 3 3 0 CSS motif domain associated with EAL MpPF26 PF07666.11 CDJ97351.1 - 4.5 7.4 9.5 14 5.8 2.0 3.6 4 0 0 4 4 4 0 M penetrans paralogue family 26 7TM_GPCR_Srbc PF10316.9 CDJ97352.1 - 2.3e-15 56.9 6.0 2.9e-15 56.5 6.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srsx PF10320.9 CDJ97352.1 - 1.6e-09 37.5 5.9 2.1e-09 37.2 5.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 CDJ97352.1 - 0.00014 21.3 2.2 0.0012 18.3 2.2 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CDJ97352.1 - 0.0029 17.3 7.5 0.013 15.2 7.5 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 CDJ97352.1 - 0.011 15.0 5.8 0.082 12.2 0.4 2.3 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw Promethin PF16015.5 CDJ97352.1 - 0.053 13.4 0.1 0.053 13.4 0.1 2.4 1 1 1 2 2 2 0 Promethin DUF3169 PF11368.8 CDJ97352.1 - 0.055 13.0 1.9 0.084 12.4 1.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3169) 7TM_GPCR_Srz PF10325.9 CDJ97352.1 - 0.46 9.8 6.9 1.1 8.5 7.0 1.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz 7TM_GPCR_Srt PF10321.9 CDJ97352.1 - 0.72 8.8 7.7 8.2 5.3 7.7 2.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt Trypan_PARP PF05887.11 CDJ97353.1 - 1.9e-07 31.1 119.4 0.02 14.9 2.9 6.9 3 1 0 3 3 3 2 Procyclic acidic repetitive protein (PARP) Trypan_PARP PF05887.11 CDJ97354.1 - 0.022 14.7 38.8 1.8e+04 -8.0 38.8 2.1 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Trypan_PARP PF05887.11 CDJ97355.1 - 0.024 14.6 2.8 0.027 14.5 2.8 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ER-remodelling PF14755.6 CDJ97355.1 - 6.5 7.0 14.4 8.3 6.7 14.4 1.2 1 0 0 1 1 1 0 Intracellular membrane remodeller Pkinase_Tyr PF07714.17 CDJ97356.1 - 1.9e-47 161.7 0.0 2.8e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kunitz_BPTI PF00014.23 CDJ97356.1 - 7.1e-33 112.6 28.1 5.4e-18 65.0 10.2 3.6 3 0 0 3 3 3 3 Kunitz/Bovine pancreatic trypsin inhibitor domain Pkinase PF00069.25 CDJ97356.1 - 6.8e-31 107.6 0.0 9.7e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Lustrin_cystein PF14625.6 CDJ97356.1 - 6.5e-14 52.0 46.9 4.2e-06 27.0 5.5 4.7 5 1 0 5 5 5 3 Lustrin, cysteine-rich repeated domain Kinase-like PF14531.6 CDJ97356.1 - 0.033 13.5 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.17 CDJ97357.1 - 1.8e-43 148.7 0.1 6.9e-43 146.8 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ97357.1 - 4.9e-28 98.2 0.0 1.7e-27 96.4 0.0 1.5 1 1 1 2 2 2 1 Protein kinase domain SH2 PF00017.24 CDJ97357.1 - 1.4e-07 31.5 0.0 3.1e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 SH2 domain FANCI_S2 PF14676.6 CDJ97358.1 - 0.00021 21.6 0.7 0.0011 19.2 0.5 2.3 1 1 1 2 2 2 1 FANCI solenoid 2 FancD2 PF14631.6 CDJ97359.1 - 6.7e-24 83.5 3.3 1.1e-23 82.8 0.1 2.6 3 1 0 3 3 3 1 Fanconi anaemia protein FancD2 nuclease Phage_holin_2_4 PF16082.5 CDJ97359.1 - 0.076 12.8 0.4 0.43 10.3 0.0 2.4 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like WI12 PF07107.11 CDJ97359.1 - 0.081 13.1 0.0 0.46 10.6 0.0 2.1 2 0 0 2 2 2 0 Wound-induced protein WI12 Neur_chan_LBD PF02931.23 CDJ97361.1 - 7.9e-29 100.6 0.4 1.7e-28 99.6 0.1 1.6 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Pkinase_Tyr PF07714.17 CDJ97362.1 - 1.3e-56 191.7 0.0 1.8e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ97362.1 - 2.5e-35 122.1 0.0 4e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDJ97362.1 - 0.0003 20.8 0.0 0.0011 19.0 0.0 2.0 2 0 0 2 2 2 1 SH2 domain Kinase-like PF14531.6 CDJ97362.1 - 0.0053 16.1 0.1 0.013 14.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like COG5 PF10392.9 CDJ97362.1 - 0.05 13.8 1.3 0.095 12.9 1.3 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF2730 PF10805.8 CDJ97362.1 - 0.17 12.0 2.0 9.9 6.3 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Cse1 PF08506.10 CDJ97363.1 - 1.9e-122 408.7 1.0 1.9e-122 408.7 1.0 1.7 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.15 CDJ97363.1 - 3.1e-60 203.9 0.5 8.2e-60 202.5 0.1 1.8 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 CDJ97363.1 - 4e-13 49.1 0.0 1.4e-12 47.4 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 CDJ97363.1 - 0.0025 16.4 2.5 2.3 6.7 0.0 3.2 2 1 0 2 2 2 2 Adaptin N terminal region Xpo1 PF08389.12 CDJ97363.1 - 0.0052 16.8 0.5 0.076 13.1 0.1 3.1 3 0 0 3 3 3 1 Exportin 1-like protein Adeno_E1B_19K PF01691.16 CDJ97363.1 - 0.022 14.3 0.3 7.9 6.0 0.0 3.5 3 0 0 3 3 3 0 Adenovirus E1B 19K protein / small t-antigen PUF PF00806.19 CDJ97363.1 - 0.031 14.0 0.0 28 4.7 0.0 4.0 3 1 0 3 3 3 0 Pumilio-family RNA binding repeat Ints3 PF10189.9 CDJ97363.1 - 0.059 12.6 1.4 0.2 10.9 0.6 2.3 2 0 0 2 2 2 0 Integrator complex subunit 3 APG6 PF04111.12 CDJ97365.1 - 1.3e-14 54.6 0.2 1.4e-14 54.4 0.2 1.0 1 0 0 1 1 1 1 Apg6 BARA domain APG6 PF04111.12 CDJ97366.1 - 1.1e-24 87.3 0.0 2.1e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 CDJ97366.1 - 1.1e-20 74.5 21.8 1.5e-20 74.1 21.8 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 CDJ97366.1 - 0.036 14.3 9.5 4.7 7.5 8.1 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding FapA PF03961.13 CDJ97366.1 - 0.04 12.5 1.3 0.051 12.2 1.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DZR PF12773.7 CDJ97366.1 - 0.046 13.8 2.2 0.91 9.6 0.3 2.5 2 0 0 2 2 2 0 Double zinc ribbon Atg14 PF10186.9 CDJ97366.1 - 0.15 11.1 6.1 0.27 10.3 6.1 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3584 PF12128.8 CDJ97366.1 - 0.22 9.0 11.6 0.3 8.5 11.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) YabA PF06156.13 CDJ97366.1 - 0.31 11.7 4.8 0.46 11.2 3.8 1.8 1 1 1 2 2 2 0 Initiation control protein YabA UPF0242 PF06785.11 CDJ97366.1 - 1.2 9.3 9.6 2.4 8.2 9.6 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Phage_tail_APC PF16778.5 CDJ97366.1 - 5 7.1 7.1 1.1 9.2 0.3 2.8 2 1 1 3 3 3 0 Phage tail assembly chaperone protein DivIC PF04977.15 CDJ97366.1 - 8.7 6.2 8.8 0.69 9.7 1.8 2.6 1 1 2 3 3 3 0 Septum formation initiator Methyltransf_11 PF08241.12 CDJ97370.1 - 5e-18 65.5 0.3 1.2e-17 64.4 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ97370.1 - 3e-15 56.7 0.8 9.3e-15 55.1 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain CMAS PF02353.20 CDJ97370.1 - 3.1e-13 49.6 0.0 4.5e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 CDJ97370.1 - 4.6e-13 49.2 0.1 7.5e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ97370.1 - 3.7e-10 39.5 0.0 6e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 CDJ97370.1 - 4e-09 36.5 0.0 7e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ97370.1 - 2.6e-08 34.5 0.0 5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CDJ97370.1 - 0.0021 18.0 0.0 0.0058 16.5 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_4 PF02390.17 CDJ97370.1 - 0.0055 16.2 0.1 0.013 15.0 0.1 1.6 1 0 0 1 1 1 1 Putative methyltransferase Sterol_MT_C PF08498.10 CDJ97370.1 - 0.036 14.4 0.0 0.082 13.2 0.0 1.5 1 0 0 1 1 1 0 Sterol methyltransferase C-terminal Methyltransf_2 PF00891.18 CDJ97370.1 - 0.067 12.5 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 O-methyltransferase domain PCMT PF01135.19 CDJ97370.1 - 0.15 11.8 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 CDJ97370.1 - 0.16 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase LON_substr_bdg PF02190.16 CDJ97371.1 - 9.9e-11 41.9 0.0 1.7e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Yippee-Mis18 PF03226.14 CDJ97371.1 - 2.4e-05 24.5 0.1 4.5e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2379 PF09543.10 CDJ97371.1 - 0.079 13.2 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) RRM_1 PF00076.22 CDJ97372.1 - 6e-25 86.9 0.4 9e-13 47.9 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ97372.1 - 9.7e-11 41.4 0.0 1.7e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 CDJ97372.1 - 2.9e-06 26.9 0.0 0.0052 16.4 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 CDJ97372.1 - 0.00076 19.3 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) DUF1027 PF06265.11 CDJ97372.1 - 0.014 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) DUF3887 PF13026.6 CDJ97372.1 - 0.087 13.7 0.0 0.2 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3887) PHM7_cyt PF14703.6 CDJ97372.1 - 0.13 12.4 0.5 5.6 7.2 0.0 2.7 2 2 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter HSCB_C PF07743.13 CDJ97373.1 - 2.7e-15 56.6 2.3 9.2e-14 51.7 0.6 2.3 2 0 0 2 2 2 2 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 CDJ97373.1 - 1.5e-07 31.5 0.4 2.8e-07 30.5 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain HscB_4_cys PF18256.1 CDJ97373.1 - 0.028 14.2 6.0 0.074 12.9 6.0 1.7 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif Transketolase_N PF00456.21 CDJ97374.1 - 6.9e-48 163.3 0.1 1.2e-47 162.5 0.1 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CDJ97374.1 - 1.3e-37 129.1 0.0 2.5e-37 128.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CDJ97374.1 - 7.4e-33 113.1 0.1 1.4e-32 112.2 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 CDJ97374.1 - 2e-12 46.7 0.2 3.2e-12 46.0 0.2 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CDJ97374.1 - 7.1e-06 25.4 0.1 0.013 14.7 0.1 2.6 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.10 CDJ97374.1 - 0.00093 18.1 0.1 0.0015 17.4 0.1 1.3 1 0 0 1 1 1 1 XFP N-terminal domain CHASE2 PF05226.11 CDJ97374.1 - 0.0012 18.6 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 CHASE2 domain TPP_enzyme_C PF02775.21 CDJ97374.1 - 0.0021 17.8 0.3 0.015 15.1 0.3 2.4 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DHDPS PF00701.22 CDJ97374.1 - 0.0067 15.2 0.0 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Aldedh PF00171.22 CDJ97375.1 - 3.5e-171 569.8 0.0 4.8e-171 569.3 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Formyl_trans_N PF00551.19 CDJ97375.1 - 1e-40 139.4 0.0 1.9e-40 138.5 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 CDJ97375.1 - 6.8e-11 42.3 0.0 1.8e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain PP-binding PF00550.25 CDJ97375.1 - 7e-05 23.1 0.0 0.00017 21.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF1487 PF07368.11 CDJ97375.1 - 0.046 13.2 0.0 0.17 11.3 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Hydrolase_4 PF12146.8 CDJ97376.1 - 1.8e-09 37.2 0.0 0.00077 18.8 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ97376.1 - 2.4e-06 27.4 0.0 0.013 15.1 0.0 2.9 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 CDJ97376.1 - 0.0031 17.4 0.0 2.3 8.0 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase LIP PF03583.14 CDJ97376.1 - 0.0064 15.9 0.0 0.009 15.4 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase Ser_hydrolase PF06821.13 CDJ97376.1 - 0.0094 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Peptidase_S9 PF00326.21 CDJ97376.1 - 0.043 13.3 0.0 0.069 12.6 0.0 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family FSH1 PF03959.13 CDJ97376.1 - 0.066 12.9 0.0 0.082 12.6 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.18 CDJ97376.1 - 0.11 12.1 0.0 0.27 10.7 0.0 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family MFS_1 PF07690.16 CDJ97377.1 - 3.3e-38 131.5 44.7 1.7e-35 122.6 31.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CDJ97377.1 - 0.039 12.2 0.0 0.039 12.2 0.0 2.8 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family ketoacyl-synt PF00109.26 CDJ97377.1 - 0.76 9.3 2.5 21 4.6 0.1 2.3 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Orf78 PF06024.12 CDJ97378.1 - 0.5 10.7 2.4 0.6 10.4 1.6 1.5 1 1 0 1 1 1 0 Orf78 (ac78) CDC45 PF02724.14 CDJ97381.1 - 0.29 9.4 33.9 0.35 9.1 33.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CDJ97381.1 - 0.47 9.2 21.0 0.69 8.6 21.0 1.4 1 0 0 1 1 1 0 Presenilin Hamartin PF04388.12 CDJ97381.1 - 5.2 5.6 15.6 6.2 5.4 15.6 1.0 1 0 0 1 1 1 0 Hamartin protein AAA_11 PF13086.6 CDJ97381.1 - 7.1 6.3 22.6 12 5.6 22.6 1.4 1 0 0 1 1 1 0 AAA domain Gal-bind_lectin PF00337.22 CDJ97382.1 - 2.5e-25 88.5 1.4 3.5e-25 88.1 1.4 1.2 1 0 0 1 1 1 1 Galactoside-binding lectin DUF1080 PF06439.11 CDJ97382.1 - 0.067 13.3 0.0 0.079 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1080) 7TM_GPCR_Srv PF10323.9 CDJ97383.1 - 1.7e-08 34.2 4.6 1.9e-08 34.0 4.6 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv NPCC PF08058.11 CDJ97383.1 - 0.0037 17.3 2.1 0.0047 17.0 2.1 1.1 1 0 0 1 1 1 1 Nuclear pore complex component Voltage_CLC PF00654.20 CDJ97383.1 - 0.0051 16.1 0.3 0.0054 16.0 0.3 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel Phage_holin_3_6 PF07332.11 CDJ97383.1 - 0.047 13.7 0.3 0.79 9.8 0.0 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III EI24 PF07264.11 CDJ97383.1 - 0.055 13.7 3.4 0.069 13.4 3.4 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF565 PF04483.12 CDJ97383.1 - 0.059 13.9 1.7 0.11 13.1 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF565) 7TM_GPCR_Sra PF02117.16 CDJ97383.1 - 0.098 11.5 5.0 0.12 11.1 5.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sra PV-1 PF06637.11 CDJ97383.1 - 0.25 10.1 0.5 0.3 9.9 0.5 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Ndc1_Nup PF09531.10 CDJ97383.1 - 0.31 9.7 3.4 0.37 9.4 3.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cortexin PF11057.8 CDJ97383.1 - 9.5 6.2 7.2 19 5.2 1.2 2.2 1 1 0 2 2 2 0 Cortexin of kidney Actin PF00022.19 CDJ97384.1 - 4.3e-140 466.9 0.0 1.4e-139 465.2 0.0 1.7 1 1 0 1 1 1 1 Actin Asp PF00026.23 CDJ97385.1 - 6.3e-55 186.8 1.5 7.7e-55 186.5 1.5 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Phage_XkdX PF09693.10 CDJ97385.1 - 0.1 12.7 0.3 0.22 11.6 0.3 1.5 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) Asp_protease_2 PF13650.6 CDJ97385.1 - 0.17 12.6 0.0 2.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease Antimicrobial12 PF08107.11 CDJ97385.1 - 0.23 11.3 0.1 0.44 10.4 0.1 1.4 1 0 0 1 1 1 0 Pleurocidin family Asp PF00026.23 CDJ97386.1 - 4.9e-80 269.3 0.8 6.4e-64 216.3 0.3 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ97386.1 - 5.9e-11 42.9 6.9 6.9e-10 39.4 6.9 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ97386.1 - 3.5e-05 23.7 0.0 8.7e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CDJ97386.1 - 0.0024 18.5 0.1 2.5 8.8 0.0 3.2 2 1 0 2 2 2 2 Aspartyl protease Collagen PF01391.18 CDJ97387.1 - 4.4e-28 96.8 91.3 1.9e-10 40.3 30.4 4.1 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ97387.1 - 0.29 11.2 0.2 0.4 10.8 0.2 1.2 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Pmp3 PF01679.17 CDJ97390.1 - 1.6e-11 44.2 13.7 2.1e-11 43.8 13.7 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF2207 PF09972.9 CDJ97390.1 - 0.056 12.2 0.5 0.061 12.1 0.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sigma_reg_N PF13800.6 CDJ97390.1 - 0.4 11.0 2.7 8.4 6.8 0.1 2.1 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Pex24p PF06398.11 CDJ97390.1 - 0.51 9.3 2.1 0.6 9.0 2.1 1.0 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin ShK PF01549.24 CDJ97391.1 - 3.2e-26 91.5 77.8 4.9e-08 33.4 9.5 5.2 5 0 0 5 5 5 4 ShK domain-like Tyrosinase PF00264.20 CDJ97391.1 - 2e-17 64.2 0.3 4.1e-17 63.2 0.3 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase zf-CCCH PF00642.24 CDJ97391.1 - 0.046 13.6 9.7 0.29 11.1 0.2 4.7 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF4210 PF13915.6 CDJ97392.1 - 1.1e-10 41.9 0.0 4e-10 40.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 CDJ97392.1 - 4.7e-09 36.3 0.1 1.3e-08 34.9 0.1 1.7 1 0 0 1 1 1 1 Chromosome segregation during meiosis TRC8_N PF13705.6 CDJ97394.1 - 6.1e-97 325.6 32.1 7.4e-97 325.3 32.1 1.0 1 0 0 1 1 1 1 TRC8 N-terminal domain zf-RING_2 PF13639.6 CDJ97394.1 - 2e-09 37.6 9.1 4.2e-09 36.6 9.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ97394.1 - 3.8e-08 33.0 9.8 8.5e-08 31.9 9.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ97394.1 - 2.4e-07 30.5 8.8 4.9e-07 29.5 8.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDJ97394.1 - 2.7e-06 27.6 10.8 1.7e-05 25.0 10.8 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CDJ97394.1 - 0.00024 21.0 8.4 0.00044 20.2 8.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 CDJ97394.1 - 0.00051 19.7 8.2 0.00051 19.7 8.2 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 CDJ97394.1 - 0.0013 18.6 6.6 0.0024 17.7 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ97394.1 - 0.0018 18.3 2.4 0.0018 18.3 2.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CDJ97394.1 - 0.0046 16.8 6.6 0.0093 15.8 6.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CDJ97394.1 - 0.01 15.5 6.4 0.03 14.0 6.4 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CDJ97394.1 - 0.043 13.9 5.5 0.27 11.3 5.5 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 CDJ97394.1 - 1.3 9.3 6.3 2.1 8.6 3.9 2.4 1 1 1 2 2 2 0 FANCL C-terminal domain RINGv PF12906.7 CDJ97394.1 - 1.5 9.0 8.9 3.3 7.9 8.9 1.6 1 0 0 1 1 1 0 RING-variant domain zf-P11 PF03854.14 CDJ97394.1 - 5.9 6.6 8.9 25 4.6 6.2 3.1 2 1 1 3 3 3 0 P-11 zinc finger ATP-synt_D PF01813.17 CDJ97395.1 - 0.053 13.4 0.1 0.23 11.3 0.1 1.9 1 1 0 1 1 1 0 ATP synthase subunit D C12orf66_like PF09404.10 CDJ97396.1 - 4.8e-44 150.9 0.8 6.7e-44 150.4 0.8 1.0 1 0 0 1 1 1 1 KICSTOR complex C12orf66 like Exo_endo_phos_2 PF14529.6 CDJ97397.1 - 6.2e-05 22.8 0.3 0.00018 21.3 0.0 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ97397.1 - 0.0051 16.4 0.0 0.0077 15.8 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family EF-hand_7 PF13499.6 CDJ97399.1 - 5e-24 84.5 10.2 2.3e-08 34.3 0.4 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 CDJ97399.1 - 2.2e-21 73.7 13.8 0.00064 19.1 0.0 6.4 6 0 0 6 6 6 6 EF hand EF-hand_6 PF13405.6 CDJ97399.1 - 5.5e-18 63.3 8.0 0.0028 17.5 0.1 6.2 6 0 0 6 6 6 5 EF-hand domain EF-hand_5 PF13202.6 CDJ97399.1 - 1.6e-15 55.8 18.6 2.8e-05 23.4 0.4 6.3 6 0 0 6 6 6 4 EF hand EF-hand_8 PF13833.6 CDJ97399.1 - 2.3e-14 53.0 15.5 0.0021 17.8 0.0 5.7 5 1 1 6 6 6 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ97399.1 - 5e-06 26.8 5.5 0.23 11.8 0.2 3.3 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region CCDC32 PF14989.6 CDJ97399.1 - 0.01 15.8 0.6 0.033 14.2 0.1 2.2 2 1 0 2 2 2 0 Coiled-coil domain containing 32 EF-hand_10 PF14788.6 CDJ97399.1 - 0.053 13.4 0.1 19 5.2 0.0 3.2 3 0 0 3 3 3 0 EF hand Unstab_antitox PF09720.10 CDJ97399.1 - 0.13 12.3 0.4 27 4.9 0.0 3.3 3 0 0 3 3 3 0 Putative addiction module component Dockerin_1 PF00404.18 CDJ97399.1 - 0.17 12.1 13.3 1.8e+02 2.4 0.0 5.0 4 1 0 4 4 4 0 Dockerin type I domain HCO3_cotransp PF00955.21 CDJ97400.1 - 1.1e-223 743.7 10.9 1.3e-223 743.4 10.9 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 CDJ97400.1 - 2.9e-98 328.9 0.0 4.2e-98 328.4 0.0 1.2 1 0 0 1 1 1 1 Band 3 cytoplasmic domain PTS_EIIA_2 PF00359.22 CDJ97400.1 - 0.0019 18.1 0.0 0.04 13.8 0.0 2.4 2 0 0 2 2 2 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 CusF_Ec PF11604.8 CDJ97400.1 - 0.028 14.4 0.1 15 5.6 0.0 2.9 3 0 0 3 3 3 0 Copper binding periplasmic protein CusF Carb_anhydrase PF00194.21 CDJ97401.1 - 1.5e-60 204.9 0.0 1.9e-60 204.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF2076 PF09849.9 CDJ97403.1 - 3.4 7.7 10.3 4.3 7.3 10.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Retrotrans_gag PF03732.17 CDJ97405.1 - 0.018 15.3 0.1 0.036 14.3 0.1 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein SCAI PF12070.8 CDJ97405.1 - 0.09 11.6 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein SCAI ARGLU PF15346.6 CDJ97408.1 - 1 9.3 9.1 28 4.6 9.1 2.2 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 DUF4816 PF16086.5 CDJ97408.1 - 1.2 9.1 6.2 1.3e+02 2.6 6.2 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4816) YTV PF07639.11 CDJ97408.1 - 1.8 8.7 34.3 1.8e+04 -10.5 34.3 3.1 1 1 0 1 1 1 0 YTV ERAP1_C PF11838.8 CDJ97410.1 - 2.9e-16 59.9 0.0 3.8e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 ERAP1-like C-terminal domain MvaI_BcnI PF15515.6 CDJ97410.1 - 0.0017 18.2 1.5 0.003 17.4 0.3 1.8 2 0 0 2 2 2 1 MvaI/BcnI restriction endonuclease family Tap-RNA_bind PF09162.10 CDJ97410.1 - 0.028 14.3 0.3 0.052 13.4 0.3 1.6 1 1 0 1 1 1 0 Tap, RNA-binding ERAP1_C PF11838.8 CDJ97412.1 - 2.7e-19 69.9 0.0 3.3e-19 69.6 0.0 1.0 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 CDJ97413.1 - 4.5e-57 193.1 0.4 5e-57 193.0 0.4 1.0 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M61 PF05299.12 CDJ97413.1 - 0.094 13.1 5.3 8.2 6.9 3.7 3.1 1 1 1 2 2 2 0 M61 glycyl aminopeptidase RVT_1 PF00078.27 CDJ97414.1 - 1e-42 146.2 0.0 1.5e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Filament PF00038.21 CDJ97416.1 - 4.1e-13 49.6 8.7 6e-13 49.1 8.7 1.2 1 0 0 1 1 1 1 Intermediate filament protein Mei5 PF10376.9 CDJ97416.1 - 0.064 13.1 2.4 0.1 12.5 2.4 1.4 1 0 0 1 1 1 0 Double-strand recombination repair protein APG6_N PF17675.1 CDJ97416.1 - 0.1 13.1 6.0 0.2 12.1 6.0 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Actin PF00022.19 CDJ97417.1 - 6e-140 466.5 0.0 1.9e-139 464.8 0.0 1.7 1 1 0 1 1 1 1 Actin HMMR_N PF15905.5 CDJ97418.1 - 0.0013 18.3 39.3 0.0013 18.3 39.3 8.3 2 2 5 7 7 7 1 Hyaluronan mediated motility receptor N-terminal GAS PF13851.6 CDJ97418.1 - 0.0035 16.7 18.1 0.0035 16.7 18.1 10.2 2 2 7 10 10 10 5 Growth-arrest specific micro-tubule binding EGL-1 PF11430.8 CDJ97418.1 - 6.2 6.8 9.4 12 5.9 0.1 3.3 4 0 0 4 4 4 0 Programmed cell death activator EGL-1 Mito_fiss_reg PF05308.11 CDJ97419.1 - 5.7 7.0 8.0 10 6.1 8.0 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator Pro_dh PF01619.18 CDJ97420.1 - 8.4e-36 124.0 0.1 1e-33 117.2 0.0 2.7 1 1 1 2 2 2 2 Proline dehydrogenase Herpes_UL51 PF04540.13 CDJ97420.1 - 0.046 13.4 0.1 0.097 12.4 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus UL51 protein Tctex-1 PF03645.13 CDJ97420.1 - 0.12 12.7 0.8 19 5.6 0.0 2.7 2 1 1 3 3 3 0 Tctex-1 family DDE_Tnp_1_7 PF13843.6 CDJ97422.1 - 3.6e-58 197.5 0.0 4.9e-58 197.1 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 C1_4 PF07975.12 CDJ97422.1 - 0.016 15.4 5.1 0.016 15.4 5.1 1.9 2 0 0 2 2 2 0 TFIIH C1-like domain IBR PF01485.21 CDJ97422.1 - 0.03 14.6 6.1 0.092 13.0 6.1 1.9 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Neur_chan_LBD PF02931.23 CDJ97423.1 - 4.2e-46 157.1 0.1 5.6e-46 156.7 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ97423.1 - 4e-35 122.0 9.6 5.8e-35 121.5 9.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Piwi PF02171.17 CDJ97426.1 - 4e-66 223.3 0.1 6.4e-66 222.7 0.1 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 CDJ97426.1 - 1.3e-11 44.4 0.3 2.9e-11 43.3 0.3 1.6 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 CDJ97426.1 - 5.8e-09 36.2 0.0 2.4e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoN PF16486.5 CDJ97426.1 - 0.00022 21.8 0.6 0.00075 20.1 0.2 2.1 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoMid PF16487.5 CDJ97426.1 - 0.00045 20.4 0.9 0.0015 18.7 0.1 2.3 3 0 0 3 3 3 1 Mid domain of argonaute Gemin6 PF06372.12 CDJ97427.1 - 2.6e-15 56.3 0.0 3.2e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Gemin6 protein DUF4224 PF13986.6 CDJ97427.1 - 0.082 12.8 0.0 0.19 11.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) Tmp39 PF10271.9 CDJ97428.1 - 3.6e-115 385.4 13.5 4.3e-115 385.2 13.5 1.0 1 0 0 1 1 1 1 Putative transmembrane protein VbhA PF18495.1 CDJ97428.1 - 0.11 12.3 0.0 0.44 10.4 0.0 1.9 2 0 0 2 2 2 0 Antitoxin VbhA S10_plectin PF03501.15 CDJ97429.1 - 4.3e-41 138.9 0.1 5.8e-41 138.5 0.1 1.2 1 0 0 1 1 1 1 Plectin/S10 domain Ribosomal_L24e PF01246.20 CDJ97430.1 - 1.8e-25 88.9 0.4 1.8e-25 88.9 0.4 2.3 2 1 0 2 2 2 1 Ribosomal protein L24e DUF775 PF05603.12 CDJ97430.1 - 0.081 12.4 1.1 0.1 12.1 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Exo_endo_phos PF03372.23 CDJ97432.1 - 0.0017 17.9 0.0 0.0036 16.8 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CDJ97432.1 - 0.029 14.2 0.0 0.063 13.1 0.0 1.7 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase DUF1759 PF03564.15 CDJ97433.1 - 4.6e-24 85.0 0.7 4.6e-24 85.0 0.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 CDJ97433.1 - 1.1e-09 38.3 0.0 3.3e-09 36.7 0.0 1.8 1 1 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 CDJ97433.1 - 2.4e-05 24.9 0.0 9.3e-05 23.0 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 CDJ97433.1 - 0.0016 18.4 19.9 0.0018 18.3 3.3 3.8 3 0 0 3 3 3 1 Zinc knuckle gag-asp_proteas PF13975.6 CDJ97433.1 - 0.0023 18.4 0.4 0.018 15.6 0.0 2.7 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ97433.1 - 0.0045 16.8 0.0 0.0094 15.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.8 CDJ97433.1 - 0.0071 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Ty3 transposon peptidase NPV_P10 PF05531.12 CDJ97433.1 - 0.81 10.2 2.7 8 7.0 0.6 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Kelch_1 PF01344.25 CDJ97434.1 - 3.6e-20 71.3 0.7 2e-08 33.7 0.2 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 CDJ97434.1 - 6.3e-10 39.0 0.0 0.00098 19.3 0.1 3.3 3 0 0 3 3 3 2 Kelch motif BTB PF00651.31 CDJ97434.1 - 6.9e-06 26.3 0.0 1.1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 CDJ97434.1 - 0.00017 21.5 0.4 0.0058 16.6 0.1 2.8 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ97434.1 - 0.00027 21.1 0.1 0.039 14.2 0.1 3.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ97434.1 - 0.0064 16.5 0.1 3.6 7.7 0.0 3.2 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 CDJ97434.1 - 0.043 13.8 0.0 4.4 7.4 0.0 3.2 3 0 0 3 3 3 0 Kelch motif PQQ_3 PF13570.6 CDJ97434.1 - 0.092 13.3 0.3 0.67 10.5 0.1 2.4 3 0 0 3 3 3 0 PQQ-like domain HTH_23 PF13384.6 CDJ97435.1 - 6.7e-11 41.7 0.2 8.8e-06 25.4 0.0 2.4 2 0 0 2 2 2 2 Homeodomain-like domain HTH_29 PF13551.6 CDJ97435.1 - 1.3e-07 31.5 0.8 2.2e-06 27.6 0.1 2.4 1 1 1 2 2 2 1 Winged helix-turn helix HTH_11 PF08279.12 CDJ97435.1 - 1.5e-06 28.1 0.6 0.00027 20.8 0.1 2.4 2 0 0 2 2 2 1 HTH domain HTH_24 PF13412.6 CDJ97435.1 - 8.3e-06 25.3 0.6 0.0014 18.1 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 CDJ97435.1 - 2.5e-05 24.3 0.4 0.012 15.7 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.6 CDJ97435.1 - 2.7e-05 24.7 0.6 5.1e-05 23.8 0.6 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_50 PF18024.1 CDJ97435.1 - 0.00011 21.7 3.1 0.0003 20.3 0.3 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_AsnC-type PF13404.6 CDJ97435.1 - 0.00012 21.9 0.1 0.017 15.0 0.0 2.6 2 1 0 2 2 2 1 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 CDJ97435.1 - 0.00017 21.4 0.5 0.19 11.6 0.0 2.4 2 0 0 2 2 2 2 MarR family HTH_Tnp_IS630 PF01710.16 CDJ97435.1 - 0.0005 20.1 0.8 0.00071 19.6 0.8 1.3 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 CDJ97435.1 - 0.00092 19.4 3.4 0.00092 19.4 3.4 2.2 2 0 0 2 2 2 1 Transposase GerE PF00196.19 CDJ97435.1 - 0.001 18.5 0.3 0.14 11.7 0.0 2.5 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_38 PF13936.6 CDJ97435.1 - 0.0013 18.5 4.5 0.036 13.8 0.5 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_22 PF13309.6 CDJ97435.1 - 0.0017 18.4 0.8 0.66 10.1 0.2 2.6 2 1 0 2 2 2 1 HTH domain PAX PF00292.18 CDJ97435.1 - 0.0022 17.9 0.4 0.0035 17.3 0.4 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_6 PF01418.17 CDJ97435.1 - 0.0042 17.0 0.1 0.11 12.5 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family HTH_18 PF12833.7 CDJ97435.1 - 0.0051 17.1 0.1 0.049 13.9 0.1 2.3 1 1 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 CDJ97435.1 - 0.0053 16.6 0.2 2.1 8.3 0.0 2.4 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB LZ_Tnp_IS481 PF13011.6 CDJ97435.1 - 0.006 17.1 1.5 2.7 8.6 0.4 2.3 1 1 1 2 2 2 2 leucine-zipper of insertion element IS481 DUF4423 PF14394.6 CDJ97435.1 - 0.0061 16.3 0.7 0.3 10.8 0.7 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4423) TnsD PF15978.5 CDJ97435.1 - 0.0066 15.5 1.9 0.11 11.5 2.3 1.9 1 1 1 2 2 2 1 Tn7-like transposition protein D HTH_Crp_2 PF13545.6 CDJ97435.1 - 0.0077 16.2 0.8 0.047 13.7 0.3 2.1 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_10 PF04967.12 CDJ97435.1 - 0.0078 16.0 0.2 0.58 10.0 0.1 2.3 2 0 0 2 2 2 1 HTH DNA binding domain Sigma70_r4_2 PF08281.12 CDJ97435.1 - 0.014 15.1 0.3 0.25 11.0 0.1 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_7 PF02796.15 CDJ97435.1 - 0.015 15.4 2.6 1.9 8.6 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_36 PF13730.6 CDJ97435.1 - 0.017 15.1 4.5 0.31 11.0 0.1 3.0 3 1 0 3 3 2 0 Helix-turn-helix domain GntR PF00392.21 CDJ97435.1 - 0.029 14.0 0.1 2.1 8.1 0.1 2.9 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family HTH_13 PF11972.8 CDJ97435.1 - 0.035 14.2 0.3 3 8.0 0.0 2.3 2 0 0 2 2 2 0 HTH DNA binding domain Sigma70_r4 PF04545.16 CDJ97435.1 - 0.037 13.6 0.1 12 5.5 0.0 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 Rrf2 PF02082.20 CDJ97435.1 - 0.049 14.0 0.3 4.7 7.6 0.1 2.2 1 1 1 2 2 2 0 Transcriptional regulator HTH_20 PF12840.7 CDJ97435.1 - 0.077 13.1 0.0 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain CDC24 PF06395.11 CDJ97435.1 - 0.079 13.2 0.1 0.18 12.1 0.1 1.6 1 0 0 1 1 1 0 CDC24 Calponin MarR PF01047.22 CDJ97435.1 - 0.089 12.7 0.9 7.3 6.6 0.1 2.3 2 0 0 2 2 2 0 MarR family Fe_dep_repress PF01325.19 CDJ97435.1 - 0.092 13.0 0.0 3.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_Tnp_ISL3 PF13542.6 CDJ97435.1 - 0.17 11.3 0.8 1.9 7.9 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_30 PF13556.6 CDJ97435.1 - 0.2 11.5 0.7 1.8 8.4 0.1 2.6 3 0 0 3 3 2 0 PucR C-terminal helix-turn-helix domain Kelch_1 PF01344.25 CDJ97436.1 - 2.1e-53 177.6 3.2 2e-11 43.2 0.0 5.2 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 CDJ97436.1 - 4.1e-32 109.4 3.5 5.3e-07 29.7 0.0 5.1 1 1 4 5 5 5 5 Kelch motif Kelch_2 PF07646.15 CDJ97436.1 - 3.1e-19 68.1 3.0 0.00026 20.8 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 CDJ97436.1 - 2.5e-15 56.2 0.1 0.0039 17.1 0.1 5.1 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ97436.1 - 3.6e-09 36.7 0.4 0.34 11.3 0.0 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ97436.1 - 3.2e-05 23.8 0.1 6.3 6.9 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 CDJ97437.1 - 9.1e-46 153.2 14.4 3.9e-11 42.4 0.0 7.9 7 1 0 7 7 7 7 Kelch motif Kelch_6 PF13964.6 CDJ97437.1 - 3e-33 113.0 1.7 2.2e-06 27.8 0.0 6.2 3 2 3 6 6 6 6 Kelch motif Kelch_2 PF07646.15 CDJ97437.1 - 4.8e-12 45.4 11.1 0.032 14.2 0.0 6.7 6 2 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 CDJ97437.1 - 3e-10 39.9 3.8 1 9.4 0.0 5.9 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ97437.1 - 8.9e-10 38.6 3.2 1.5 9.2 0.1 6.2 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ97437.1 - 0.0021 18.0 4.0 4.5 7.4 0.1 5.1 5 1 0 5 5 5 1 Kelch motif AA_permease_2 PF13520.6 CDJ97438.1 - 2.4e-07 29.9 5.6 2.6e-07 29.8 5.6 1.0 1 0 0 1 1 1 1 Amino acid permease Trp_Tyr_perm PF03222.13 CDJ97438.1 - 0.0029 16.7 2.8 0.0032 16.6 2.8 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family F-box PF00646.33 CDJ97439.1 - 1.6e-06 27.9 0.0 4.7e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDJ97439.1 - 1.7e-05 24.6 0.0 4.5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like Utp12 PF04003.12 CDJ97439.1 - 0.0045 17.3 0.1 0.011 16.0 0.1 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family F-box_4 PF15966.5 CDJ97439.1 - 0.0058 16.5 0.5 0.029 14.3 0.0 2.2 2 1 1 3 3 3 1 F-box MBOAT PF03062.19 CDJ97440.1 - 7.6e-24 84.7 12.5 1.2e-23 84.1 12.5 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family RDD PF06271.12 CDJ97442.1 - 7.9e-09 35.8 0.1 1.5e-08 35.0 0.1 1.5 1 0 0 1 1 1 1 RDD family Ground-like PF04155.18 CDJ97445.1 - 7.6e-06 26.5 0.1 1.1e-05 26.0 0.1 1.1 1 0 0 1 1 1 1 Ground-like domain Somatomedin_B PF01033.17 CDJ97449.1 - 6.3e-07 29.7 6.4 6.3e-07 29.7 6.4 3.9 5 0 0 5 5 5 1 Somatomedin B domain TSP_1 PF00090.19 CDJ97449.1 - 0.00038 20.6 5.0 0.00038 20.6 5.0 2.7 2 0 0 2 2 2 1 Thrombospondin type 1 domain PTN_MK_N PF05196.13 CDJ97449.1 - 0.0036 17.5 2.3 0.015 15.5 2.3 2.1 1 0 0 1 1 1 1 PTN/MK heparin-binding protein family, N-terminal domain Amino_oxidase PF01593.24 CDJ97450.1 - 1.3e-15 57.7 0.0 2.1e-15 57.0 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ97450.1 - 4.7e-10 39.6 0.1 7.7e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CDJ97450.1 - 0.01 15.5 0.3 0.012 15.2 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CDJ97450.1 - 0.013 15.5 0.2 0.024 14.6 0.2 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 CDJ97450.1 - 0.015 14.6 0.1 0.026 13.8 0.0 1.6 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 CDJ97450.1 - 0.019 14.3 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 CDJ97450.1 - 0.044 13.0 0.1 0.052 12.8 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDJ97450.1 - 0.1 13.1 0.1 0.18 12.4 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 CDJ97450.1 - 0.12 11.2 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 MCRA family DUF2576 PF10845.8 CDJ97450.1 - 0.12 12.0 0.1 0.34 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) FAD_binding_2 PF00890.24 CDJ97450.1 - 0.13 11.3 0.1 0.17 11.0 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain vATP-synt_AC39 PF01992.16 CDJ97451.1 - 5.5e-116 387.7 2.6 6.2e-116 387.6 2.6 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit FH2 PF02181.23 CDJ97452.1 - 1.2e-66 225.4 1.8 1.2e-66 225.4 1.8 1.8 2 0 0 2 2 2 1 Formin Homology 2 Domain Formin_GBD_N PF18382.1 CDJ97452.1 - 5.6e-36 123.0 0.0 1.5e-35 121.6 0.0 1.8 1 0 0 1 1 1 1 Formin N-terminal GTPase-binding domain Drf_FH3 PF06367.16 CDJ97452.1 - 0.0087 15.7 1.6 0.0087 15.7 1.6 2.2 2 0 0 2 2 2 1 Diaphanous FH3 Domain Cyclin_N PF00134.23 CDJ97452.1 - 0.016 15.0 0.1 0.049 13.4 0.1 1.8 1 0 0 1 1 1 0 Cyclin, N-terminal domain Collagen PF01391.18 CDJ97453.1 - 5e-25 87.0 82.8 6.8e-10 38.6 26.3 4.3 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Trypsin PF00089.26 CDJ97454.1 - 1.1e-23 84.3 0.6 9.3e-23 81.2 0.6 1.9 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CDJ97454.1 - 8.7e-05 23.5 0.1 0.00013 22.8 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 CDJ97454.1 - 0.00017 21.3 0.0 0.36 10.4 0.0 2.2 2 0 0 2 2 2 2 Chymotrypsin family Peptidase-S1 DUF19 PF01579.18 CDJ97455.1 - 2.1e-09 37.4 4.3 2.5e-09 37.1 4.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF19) CPG4 PF15481.6 CDJ97455.1 - 1e-07 32.5 3.4 2.4e-07 31.3 0.4 2.2 1 1 1 2 2 2 1 Chondroitin proteoglycan 4 DUF1397 PF07165.11 CDJ97455.1 - 0.034 13.6 7.6 18 4.7 7.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1397) TBCC PF07986.12 CDJ97455.1 - 0.037 13.8 0.2 2.2 8.1 0.1 2.2 1 1 0 2 2 2 0 Tubulin binding cofactor C Fer4_21 PF14697.6 CDJ97455.1 - 2.5 8.3 5.7 1.3 9.2 1.5 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain DUF1679 PF07914.11 CDJ97456.1 - 7.8e-119 397.2 0.4 8.8e-119 397.0 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 CDJ97456.1 - 2.5e-21 76.3 0.2 5.2e-21 75.2 0.2 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 CDJ97456.1 - 7.8e-08 32.5 0.0 1.5e-07 31.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDJ97456.1 - 0.00037 20.1 0.1 0.0009 18.9 0.1 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 CDJ97456.1 - 0.011 15.0 0.1 0.027 13.7 0.1 1.7 1 1 0 1 1 1 0 Fructosamine kinase SSPI PF14098.6 CDJ97456.1 - 0.081 13.1 0.1 0.37 11.0 0.0 2.2 2 0 0 2 2 2 0 Small, acid-soluble spore protein I DUF1679 PF07914.11 CDJ97457.1 - 5.1e-126 420.9 0.0 5.8e-126 420.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 CDJ97457.1 - 1.4e-21 77.1 0.1 2.2e-21 76.4 0.1 1.5 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 CDJ97457.1 - 7.2e-14 52.3 0.0 1.1e-13 51.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 CDJ97457.1 - 2.2e-06 27.1 0.0 5.9e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 CDJ97457.1 - 0.00037 20.1 0.2 0.001 18.7 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase PAS_3 PF08447.12 CDJ97458.1 - 6.3e-14 52.0 0.3 1.9e-09 37.7 0.1 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 CDJ97458.1 - 7.9e-12 45.3 0.1 2.7e-10 40.4 0.1 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 CDJ97458.1 - 0.041 13.9 0.0 8.2 6.5 0.0 2.4 2 0 0 2 2 2 0 PAS fold Col_cuticle_N PF01484.17 CDJ97460.1 - 2.1e-21 75.7 0.5 2.7e-21 75.4 0.5 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 CDJ97460.1 - 3e-19 68.5 120.0 1.7e-07 30.9 43.0 4.0 2 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Oleosin PF01277.17 CDJ97460.1 - 0.11 12.3 0.1 0.14 11.9 0.1 1.1 1 0 0 1 1 1 0 Oleosin IBV_3B PF03622.13 CDJ97460.1 - 0.17 12.0 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 IBV 3B protein Collagen PF01391.18 CDJ97461.1 - 2.4e-23 81.6 118.0 1.1e-08 34.7 45.4 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ97461.1 - 0.00011 22.2 0.3 0.00014 21.9 0.3 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Ndc80_HEC PF03801.13 CDJ97462.1 - 1.4e-33 115.7 0.0 3.1e-33 114.6 0.0 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family FliD_N PF02465.18 CDJ97462.1 - 0.012 16.3 5.6 0.055 14.2 0.1 3.4 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus HIP1_clath_bdg PF16515.5 CDJ97462.1 - 0.018 15.7 8.8 0.018 15.7 8.8 4.3 2 2 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FtsA PF14450.6 CDJ97462.1 - 0.12 12.8 0.4 0.31 11.5 0.1 1.9 2 0 0 2 2 2 0 Cell division protein FtsA AFP_2 PF18815.1 CDJ97462.1 - 0.38 11.1 2.8 0.79 10.0 0.0 2.9 3 0 0 3 3 3 0 Bacterial antifreeze protein repeat ERM PF00769.19 CDJ97462.1 - 0.6 9.9 37.6 0.08 12.7 14.1 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Tup_N PF08581.10 CDJ97462.1 - 2 8.8 25.3 0.59 10.5 2.4 5.6 5 1 1 6 6 6 0 Tup N-terminal Seryl_tRNA_N PF02403.22 CDJ97462.1 - 7.6 6.8 38.3 5 7.4 8.1 4.5 2 2 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Bacillus_HBL PF05791.11 CDJ97462.1 - 9 6.1 15.1 39 4.0 10.1 3.9 3 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) EGF PF00008.27 CDJ97463.1 - 2.8e-91 299.3 330.4 6.9e-09 35.8 10.4 22.4 22 0 0 22 22 22 20 EGF-like domain hEGF PF12661.7 CDJ97463.1 - 2.7e-46 154.7 293.9 1.6e-05 25.4 6.1 24.2 24 0 0 24 24 22 17 Human growth factor-like EGF Ank_2 PF12796.7 CDJ97463.1 - 9.2e-29 99.9 0.4 1.7e-14 54.1 0.3 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) EGF_2 PF07974.13 CDJ97463.1 - 3e-25 88.3 378.4 0.0004 20.7 10.2 23.8 22 2 1 23 23 21 20 EGF-like domain Ank_4 PF13637.6 CDJ97463.1 - 4e-24 84.7 8.4 5.7e-09 36.3 0.1 5.1 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ97463.1 - 2.5e-23 79.6 0.6 0.00078 19.7 0.0 6.9 6 0 0 6 6 6 5 Ankyrin repeat Notch PF00066.17 CDJ97463.1 - 1.6e-22 79.7 50.3 1.9e-11 44.2 10.1 15.1 15 5 0 15 15 5 3 LNR domain EGF_CA PF07645.15 CDJ97463.1 - 2.1e-19 69.5 78.1 4.5e-08 33.2 7.3 22.1 10 7 12 22 22 17 8 Calcium-binding EGF domain Ank PF00023.30 CDJ97463.1 - 2.1e-19 69.0 0.3 1.9e-05 24.9 0.0 6.4 5 1 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CDJ97463.1 - 9.9e-17 60.8 3.3 3e-05 24.2 0.0 5.7 3 2 2 5 5 5 3 Ankyrin repeats (many copies) NOD PF06816.13 CDJ97463.1 - 2.2e-12 46.4 0.0 3.9e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 NOTCH protein NODP PF07684.12 CDJ97463.1 - 6.9e-11 42.1 0.0 3.8e-10 39.8 0.0 2.4 1 0 0 1 1 1 1 NOTCH protein EGF_3 PF12947.7 CDJ97463.1 - 0.00079 19.6 22.4 0.0021 18.2 4.9 22.5 18 3 3 22 22 19 8 EGF domain CcmD PF04995.14 CDJ97463.1 - 0.32 11.1 0.5 0.59 10.3 0.5 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) 7TM_GPCR_Srsx PF10320.9 CDJ97464.1 - 1.3e-51 175.5 24.4 1.6e-51 175.1 24.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 CDJ97464.1 - 1.1e-05 24.9 23.1 1.2e-05 24.8 22.5 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Srg PF02118.21 CDJ97464.1 - 0.00043 20.0 14.3 0.00043 20.0 14.3 2.8 1 1 1 3 3 3 1 Srg family chemoreceptor TMEM51 PF15345.6 CDJ97464.1 - 0.098 12.5 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Collagen PF01391.18 CDJ97465.1 - 1e-20 73.2 121.1 1.2e-08 34.6 44.0 4.0 2 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ97465.1 - 0.00011 22.2 0.3 0.00014 21.9 0.3 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain 7TM_GPCR_Srsx PF10320.9 CDJ97466.1 - 4.6e-52 177.0 19.4 5.4e-52 176.7 19.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 CDJ97466.1 - 7.1e-07 28.8 21.1 9.4e-07 28.4 21.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ97467.1 - 4.3e-53 180.3 19.0 4.3e-53 180.3 19.0 1.5 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 CDJ97467.1 - 3.4e-11 43.0 19.7 6.1e-11 42.2 19.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) HRG PF16954.5 CDJ97467.1 - 1.2 9.6 0.0 1.2 9.6 0.0 3.5 3 0 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Motile_Sperm PF00635.26 CDJ97468.1 - 1.1e-12 47.8 0.1 1.4e-12 47.4 0.1 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Mucin PF01456.17 CDJ97469.1 - 0.18 11.8 14.6 0.3 11.1 2.0 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF1876 PF08962.11 CDJ97470.1 - 0.12 12.4 0.6 0.14 12.1 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1876) Mucin PF01456.17 CDJ97470.1 - 7.4 6.6 21.8 9.6 6.2 21.8 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Motile_Sperm PF00635.26 CDJ97471.1 - 6.9e-15 54.8 0.8 1e-14 54.3 0.8 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain S1-like PF14444.6 CDJ97471.1 - 0.0044 16.9 0.0 0.0084 16.0 0.0 1.4 1 0 0 1 1 1 1 S1-like Chi-conotoxin PF16981.5 CDJ97472.1 - 0.28 11.4 0.8 0.41 10.9 0.8 1.3 1 0 0 1 1 1 0 chi-Conotoxin or t superfamily Mucin PF01456.17 CDJ97472.1 - 3.3 7.7 19.4 4.4 7.3 19.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.11 CDJ97472.1 - 7.3 7.0 9.5 9.3 6.7 9.5 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin RVT_1 PF00078.27 CDJ97473.1 - 3e-44 151.2 0.0 1.1e-43 149.3 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDJ97473.1 - 3.8e-06 26.8 0.0 8.5e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF3629 PF12302.8 CDJ97473.1 - 0.033 13.6 0.7 0.063 12.7 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) DivIC PF04977.15 CDJ97473.1 - 0.26 11.1 4.9 3.2 7.6 0.0 2.7 3 0 0 3 3 3 0 Septum formation initiator DNA_pol_B PF00136.21 CDJ97474.1 - 9.6e-149 496.0 0.0 1.2e-148 495.6 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CDJ97474.1 - 6.2e-69 232.7 0.0 1.3e-68 231.7 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain Glyco_hydro_47 PF01532.20 CDJ97474.1 - 2.3e-22 79.6 0.0 7.6e-14 51.5 0.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 47 zf-C4pol PF14260.6 CDJ97474.1 - 3.3e-14 53.1 4.2 8e-14 51.9 4.2 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 CDJ97474.1 - 0.0016 17.4 0.2 0.0055 15.6 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral baeRF_family3 PF18845.1 CDJ97474.1 - 0.034 14.4 0.0 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 Raptor_N PF14538.6 CDJ97476.1 - 6.6e-62 207.8 0.1 1.2e-61 206.9 0.1 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 CDJ97476.1 - 6.4e-05 22.9 0.4 0.0042 17.2 0.1 3.5 2 0 0 2 2 2 1 HEAT repeat HEAT_2 PF13646.6 CDJ97476.1 - 0.0019 18.5 0.8 0.28 11.6 0.1 3.1 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 CDJ97476.1 - 0.049 14.2 0.0 0.48 11.0 0.1 2.7 3 0 0 3 3 3 0 HEAT-like repeat RTP1_C1 PF10363.9 CDJ97476.1 - 0.057 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 WD40 PF00400.32 CDJ97476.1 - 0.35 11.8 2.6 92 4.2 0.0 4.8 4 0 0 4 4 4 0 WD domain, G-beta repeat Ribosomal_L11_N PF03946.14 CDJ97477.1 - 2.4e-24 85.0 0.2 3.6e-24 84.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CDJ97477.1 - 1e-17 64.4 0.7 1.5e-17 63.8 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain CtaG_Cox11 PF04442.14 CDJ97478.1 - 8.2e-58 194.7 0.4 1.8e-57 193.6 0.4 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 dCMP_cyt_deam_1 PF00383.23 CDJ97478.1 - 2.9e-23 81.7 0.0 6.4e-23 80.5 0.0 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region TCR PF03638.15 CDJ97478.1 - 3.7e-23 81.5 59.4 9.7e-13 48.2 24.4 3.0 3 0 0 3 3 3 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MafB19-deam PF14437.6 CDJ97478.1 - 3.8e-18 65.6 0.0 6.4e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase MSL2-CXC PF16682.5 CDJ97478.1 - 0.00017 21.7 41.5 0.0081 16.3 14.6 2.7 2 0 0 2 2 2 2 CXC domain of E3 ubiquitin-protein ligase MSL2 SNAD4 PF18750.1 CDJ97478.1 - 0.00093 19.3 0.0 0.0025 17.9 0.0 1.7 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 CDJ97478.1 - 0.0062 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 APOBEC2 APOBEC3 PF18771.1 CDJ97478.1 - 0.013 15.6 0.0 0.026 14.7 0.0 1.4 1 0 0 1 1 1 0 APOBEC3 Bd3614-deam PF14439.6 CDJ97478.1 - 0.017 15.2 0.0 0.038 14.1 0.0 1.6 1 0 0 1 1 1 0 Bd3614-like deaminase DUF2228 PF10228.9 CDJ97479.1 - 8.2e-57 192.8 0.0 1.4e-56 192.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2228) DUF3011 PF11218.8 CDJ97479.1 - 0.0038 17.2 0.0 0.0055 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3011) Beta-Casp PF10996.8 CDJ97480.1 - 1.1e-24 86.8 0.0 2.2e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain LRAT PF04970.13 CDJ97480.1 - 1.2e-24 87.0 0.0 2.2e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Lecithin retinol acyltransferase Lactamase_B_6 PF16661.5 CDJ97480.1 - 1.8e-19 69.9 0.0 3.3e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 CDJ97480.1 - 4e-14 52.3 0.0 9.5e-14 51.1 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 CDJ97480.1 - 4.3e-11 43.2 0.0 1.1e-10 41.8 0.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CDJ97480.1 - 3.7e-09 36.4 0.8 1.7e-07 31.0 0.1 2.7 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 CDJ97480.1 - 0.00027 20.3 0.0 0.00069 18.9 0.0 1.6 1 0 0 1 1 1 1 Putative beta-lactamase-like family Lactamase_B_3 PF13483.6 CDJ97480.1 - 0.0019 18.1 0.0 0.0065 16.4 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Asp-B-Hydro_N PF05279.11 CDJ97481.1 - 0.41 10.7 3.4 0.46 10.5 3.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RT_RNaseH_2 PF17919.1 CDJ97482.1 - 1.9e-35 120.9 0.2 1.1e-34 118.4 0.1 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ97482.1 - 5.3e-33 113.4 0.0 7.1e-32 109.8 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ97482.1 - 1.8e-22 79.8 0.0 6.3e-22 78.0 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CDJ97482.1 - 6.4e-22 78.2 0.0 1.2e-21 77.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ97482.1 - 1.3e-18 66.8 0.1 4.1e-18 65.2 0.1 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 CDJ97482.1 - 3.8e-08 33.8 0.1 1.3e-07 32.0 0.0 2.1 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ97482.1 - 7.7e-08 32.9 0.0 2.8e-07 31.1 0.0 2.0 2 0 0 2 2 1 1 Aspartyl protease rve_3 PF13683.6 CDJ97482.1 - 1.1e-05 25.0 0.0 5.5e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 CDJ97482.1 - 0.00016 21.8 0.1 0.00043 20.4 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RVP PF00077.20 CDJ97482.1 - 0.011 16.0 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Mcp5_PH PF12814.7 CDJ97482.1 - 0.067 13.3 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology gag-asp_proteas PF13975.6 CDJ97483.1 - 0.00021 21.8 0.1 0.00062 20.3 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Motile_Sperm PF00635.26 CDJ97485.1 - 2.6e-12 46.5 0.0 6.6e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 MSP (Major sperm protein) domain TB2_DP1_HVA22 PF03134.19 CDJ97485.1 - 0.0016 18.3 0.1 0.0031 17.4 0.1 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family 7TM_GPCR_Srsx PF10320.9 CDJ97486.1 - 1.9e-05 24.2 1.4 2.4e-05 23.9 1.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 CDJ97486.1 - 0.00045 19.6 0.3 0.00056 19.3 0.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Exo_endo_phos_2 PF14529.6 CDJ97488.1 - 1e-06 28.6 0.0 1.6e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ97488.1 - 0.065 12.8 0.1 0.085 12.4 0.1 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DB PF01682.19 CDJ97489.1 - 5.4e-16 58.7 17.6 7.7e-16 58.2 17.6 1.2 1 0 0 1 1 1 1 DB module DUF5566 PF17721.1 CDJ97491.1 - 0.0099 16.2 0.1 0.01 16.1 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5566) RT_RNaseH_2 PF17919.1 CDJ97492.1 - 1.7e-34 117.8 0.0 5.6e-34 116.2 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ97492.1 - 5.1e-30 103.9 0.0 3.3e-29 101.2 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ97492.1 - 3.3e-15 55.9 1.5 7.8e-15 54.7 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 CDJ97492.1 - 2.5e-09 37.3 0.0 6.5e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CDJ97492.1 - 0.00016 21.8 0.1 0.00036 20.7 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger CCP_MauG PF03150.14 CDJ97493.1 - 0.03 15.0 0.2 0.095 13.4 0.2 1.9 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase EspB_PE PF18625.1 CDJ97493.1 - 0.12 12.9 0.3 0.32 11.5 0.3 1.8 1 0 0 1 1 1 0 ESX-1 secreted protein B PE domain Syntaxin-6_N PF09177.11 CDJ97493.1 - 0.21 12.1 4.2 0.74 10.4 0.1 3.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal BORCS8 PF10167.9 CDJ97493.1 - 0.39 10.7 2.5 1.4 8.8 0.2 2.6 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 8 LMBR1 PF04791.16 CDJ97493.1 - 1.6 7.6 4.6 0.26 10.2 0.2 1.9 3 0 0 3 3 3 0 LMBR1-like membrane protein Neur_chan_LBD PF02931.23 CDJ97494.1 - 2.2e-52 177.6 1.9 3.3e-52 177.1 1.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ97494.1 - 2.4e-24 86.7 2.8 3.9e-24 86.0 2.8 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CDJ97495.1 - 7.2e-61 205.4 6.0 1e-60 204.9 6.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ97495.1 - 1.8e-23 83.8 0.3 2.6e-23 83.3 0.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CDJ97496.1 - 2e-57 194.1 4.8 2.6e-57 193.7 4.8 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ97496.1 - 4e-18 66.4 8.6 1.1e-17 64.9 8.6 1.7 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region zf-C4 PF00105.18 CDJ97497.1 - 1.6e-27 95.7 12.8 3.3e-27 94.7 12.8 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ97497.1 - 8.7e-22 77.7 0.2 1.5e-21 76.9 0.2 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor ASC PF00858.24 CDJ97498.1 - 3.8e-80 270.0 12.9 5.3e-80 269.5 12.9 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel SurA_N_2 PF13623.6 CDJ97498.1 - 0.11 12.4 0.4 0.6 10.0 0.0 2.3 2 0 0 2 2 2 0 SurA N-terminal domain Gluconate_2-dh3 PF13618.6 CDJ97499.1 - 0.082 13.1 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Myb_DNA-bind_7 PF15963.5 CDJ97500.1 - 3.9e-22 78.0 1.2 9.1e-22 76.8 0.6 2.1 1 1 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 CDJ97500.1 - 0.0028 17.8 0.0 0.0078 16.4 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Membr_traf_MHD PF10540.9 CDJ97502.1 - 2.9e-47 160.6 3.0 5.7e-47 159.6 3.0 1.5 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 CDJ97502.1 - 2.4e-12 47.1 0.0 5.2e-12 46.0 0.0 1.6 2 0 0 2 2 2 1 C2 domain NAD_binding_1 PF00175.21 CDJ97504.1 - 8.1e-19 68.3 0.0 1.1e-18 67.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CDJ97504.1 - 0.064 13.4 0.0 0.13 12.4 0.0 1.7 1 1 0 1 1 1 0 Ferric reductase NAD binding domain GUN4 PF05419.12 CDJ97504.1 - 0.083 13.0 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 GUN4-like DNA_pol3_delta2 PF13177.6 CDJ97504.1 - 0.12 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit HPD PF05044.12 CDJ97505.1 - 5e-23 81.7 1.6 7.9e-23 81.0 1.6 1.3 1 0 0 1 1 1 1 Homeo-prospero domain PI3K_1B_p101 PF10486.9 CDJ97505.1 - 0.35 8.6 5.4 0.42 8.3 5.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit zf-TAZ PF02135.16 CDJ97506.1 - 6.5e-08 32.9 6.3 1.3e-07 32.0 6.3 1.5 1 0 0 1 1 1 1 TAZ zinc finger Toxin_13 PF07822.11 CDJ97506.1 - 0.21 11.8 5.1 0.14 12.3 0.6 2.7 3 0 0 3 3 3 0 Neurotoxin B-IV-like protein HEAT_EZ PF13513.6 CDJ97508.1 - 7.2e-06 26.4 0.2 4.2 8.0 0.0 4.7 4 1 1 5 5 5 2 HEAT-like repeat Arm PF00514.23 CDJ97508.1 - 1.1e-05 25.3 15.7 0.11 12.6 0.2 7.5 8 2 0 8 8 8 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CDJ97508.1 - 0.00027 21.2 0.1 1.4 9.4 0.0 3.5 2 2 0 2 2 2 2 HEAT repeats IBN_N PF03810.19 CDJ97508.1 - 0.0057 16.6 0.0 2.5 8.1 0.0 3.1 3 1 0 3 3 3 1 Importin-beta N-terminal domain RICTOR_N PF14664.6 CDJ97508.1 - 0.044 12.8 0.3 0.087 11.8 0.1 1.6 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term HEAT_PBS PF03130.16 CDJ97508.1 - 0.36 11.6 4.7 39 5.3 0.0 4.9 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat RICTOR_V PF14668.6 CDJ97508.1 - 1.3 9.3 7.9 32 4.9 0.5 4.7 4 2 3 7 7 7 0 Rapamycin-insensitive companion of mTOR, domain 5 Histone PF00125.24 CDJ97510.1 - 1.4e-06 28.7 1.3 1.4e-06 28.7 1.3 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 PIN_4 PF13638.6 CDJ97510.1 - 0.019 15.2 0.9 0.031 14.6 0.6 1.5 1 1 1 2 2 2 0 PIN domain Branch PF02485.21 CDJ97511.1 - 8.7e-12 45.1 0.0 9.7e-12 44.9 0.0 1.0 1 0 0 1 1 1 1 Core-2/I-Branching enzyme DHquinase_II PF01220.19 CDJ97512.1 - 0.043 13.5 0.1 0.067 12.9 0.1 1.2 1 0 0 1 1 1 0 Dehydroquinase class II Pkinase PF00069.25 CDJ97513.1 - 4.8e-11 42.5 0.0 6.2e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Fructosamin_kin PF03881.14 CDJ97513.1 - 0.0025 17.1 0.0 0.004 16.4 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase Kdo PF06293.14 CDJ97513.1 - 0.0063 15.9 0.0 0.012 15.0 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 CDJ97513.1 - 0.049 12.9 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase USP7_ICP0_bdg PF12436.8 CDJ97513.1 - 0.075 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 PT-HINT PF07591.11 CDJ97513.1 - 0.11 12.7 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Pretoxin HINT domain FXa_inhibition PF14670.6 CDJ97514.1 - 0.07 13.4 0.4 0.099 12.9 0.4 1.1 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site SCVP PF17619.2 CDJ97515.1 - 4e-18 66.1 0.1 4.6e-18 65.9 0.1 1.1 1 0 0 1 1 1 1 Secreted clade V proteins Y_phosphatase PF00102.27 CDJ97516.1 - 2.2e-36 125.6 0.8 3.4e-36 125.0 0.8 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase GILT PF03227.16 CDJ97518.1 - 1e-26 93.2 1.8 2e-26 92.3 1.8 1.5 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) SapA PF02199.15 CDJ97518.1 - 0.0058 16.9 0.7 0.016 15.5 0.7 1.8 1 0 0 1 1 1 1 Saposin A-type domain Thioredoxin_9 PF14595.6 CDJ97518.1 - 0.096 12.5 0.2 0.18 11.6 0.2 1.4 1 0 0 1 1 1 0 Thioredoxin DUF627 PF04781.12 CDJ97518.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF627) Astacin PF01400.24 CDJ97519.1 - 1.8e-25 89.6 0.0 3.8e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 CDJ97519.1 - 0.00026 20.7 0.0 0.00044 19.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CDJ97519.1 - 0.0025 17.7 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 Matrixin PC4 PF02229.16 CDJ97519.1 - 0.0052 16.4 0.4 0.014 15.0 0.4 1.8 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Peptidase_M66 PF10462.9 CDJ97519.1 - 0.0089 15.0 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase M66 DUF4953 PF16313.5 CDJ97519.1 - 0.093 11.9 0.6 0.3 10.3 0.1 1.8 2 0 0 2 2 2 0 Met-zincin Reprolysin_3 PF13582.6 CDJ97519.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CDJ97519.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 CRAL_TRIO PF00650.20 CDJ97520.1 - 3.4e-26 91.9 0.0 4.9e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 CDJ97520.1 - 0.00012 22.5 0.1 0.6 10.6 0.0 2.3 2 0 0 2 2 2 2 Golgi-dynamics membrane-trafficking EMP24_GP25L PF01105.24 CDJ97520.1 - 0.021 14.8 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF2688 PF10892.8 CDJ97520.1 - 0.045 13.2 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) CUE PF02845.16 CDJ97520.1 - 0.065 13.0 0.3 0.12 12.1 0.3 1.4 1 0 0 1 1 1 0 CUE domain ABC_membrane PF00664.23 CDJ97521.1 - 9.1e-110 366.6 25.7 4.4e-60 203.7 12.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ97521.1 - 1.1e-70 236.5 0.3 1.1e-34 119.9 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CDJ97521.1 - 4.3e-16 59.0 1.7 7.8e-07 28.8 0.0 4.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDJ97521.1 - 3.6e-09 37.2 1.4 0.00081 19.8 0.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CDJ97521.1 - 1.6e-08 34.9 1.7 0.013 15.7 0.2 4.0 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CDJ97521.1 - 2e-07 31.1 0.1 0.004 17.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 CDJ97521.1 - 7.6e-06 26.4 0.9 0.15 12.5 0.1 4.3 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDJ97521.1 - 1.7e-05 24.8 0.1 1.1 9.3 0.0 4.0 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.9 CDJ97521.1 - 2.6e-05 23.2 0.4 0.12 11.1 0.0 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_30 PF13604.6 CDJ97521.1 - 2.8e-05 23.9 0.0 0.24 11.1 0.0 3.0 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CDJ97521.1 - 5e-05 23.0 2.0 0.16 11.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Rad17 PF03215.15 CDJ97521.1 - 0.00013 22.0 0.2 0.11 12.4 0.0 3.0 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_7 PF12775.7 CDJ97521.1 - 0.00025 20.6 0.1 0.89 9.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region MMR_HSR1 PF01926.23 CDJ97521.1 - 0.00038 20.5 0.0 0.1 12.7 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.6 CDJ97521.1 - 0.0004 20.6 4.1 0.62 10.3 0.4 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 CDJ97521.1 - 0.00054 19.6 0.0 0.35 10.4 0.0 3.2 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 CDJ97521.1 - 0.00074 19.7 6.2 0.019 15.1 1.8 3.4 3 1 0 3 3 3 1 Helicase HerA, central domain G-alpha PF00503.20 CDJ97521.1 - 0.00092 18.5 0.0 0.44 9.7 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit RNA_helicase PF00910.22 CDJ97521.1 - 0.0011 19.3 0.0 1.6 9.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_15 PF13175.6 CDJ97521.1 - 0.0015 18.3 0.0 0.89 9.2 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 CDJ97521.1 - 0.0022 17.2 0.0 0.24 10.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 CDJ97521.1 - 0.0027 17.9 0.0 3.4 7.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 CDJ97521.1 - 0.0045 16.8 0.2 11 5.7 0.0 4.0 3 2 1 5 5 5 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_17 PF13207.6 CDJ97521.1 - 0.0045 17.4 0.0 0.85 10.0 0.0 3.8 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.6 CDJ97521.1 - 0.0051 17.4 0.3 5.6 7.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.6 CDJ97521.1 - 0.0069 16.4 0.0 2.1 8.4 0.0 3.2 3 1 1 4 4 2 1 AAA domain Zeta_toxin PF06414.12 CDJ97521.1 - 0.0089 15.3 0.3 5.6 6.2 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin NB-ARC PF00931.22 CDJ97521.1 - 0.016 14.4 0.1 2.5 7.2 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain PRK PF00485.18 CDJ97521.1 - 0.016 15.0 0.1 13 5.4 0.0 3.1 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 CDJ97521.1 - 0.029 14.6 0.0 2.9 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CDJ97521.1 - 0.032 14.1 0.0 12 5.8 0.0 3.5 2 1 1 3 3 3 0 NTPase AAA_24 PF13479.6 CDJ97521.1 - 0.038 13.7 0.0 3.5 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain tRNA_lig_kinase PF08303.11 CDJ97521.1 - 0.048 13.8 0.0 11 6.1 0.0 2.8 2 0 0 2 2 2 0 tRNA ligase kinase domain ABC_membrane_2 PF06472.15 CDJ97521.1 - 0.049 13.0 1.4 0.087 12.2 0.2 2.0 2 0 0 2 2 2 0 ABC transporter transmembrane region 2 IstB_IS21 PF01695.17 CDJ97521.1 - 0.059 13.1 3.4 12 5.5 0.0 3.9 5 0 0 5 5 3 0 IstB-like ATP binding protein SRP54 PF00448.22 CDJ97521.1 - 0.064 12.9 0.0 4.4 6.9 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NACHT PF05729.12 CDJ97521.1 - 0.067 13.1 0.1 18 5.2 0.0 2.6 2 0 0 2 2 2 0 NACHT domain FeoB_N PF02421.18 CDJ97521.1 - 0.12 11.9 0.0 3.9 7.0 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Resolvase PF00239.21 CDJ97521.1 - 0.7 10.0 4.7 28 4.8 0.0 3.9 4 0 0 4 4 3 0 Resolvase, N terminal domain AAA_23 PF13476.6 CDJ97521.1 - 1.1 9.7 10.0 18 5.8 0.1 3.1 2 1 0 2 2 2 0 AAA domain RVT_1 PF00078.27 CDJ97522.1 - 1.1e-11 44.6 0.0 1.4e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Zeta_toxin PF06414.12 CDJ97523.1 - 0.0058 15.9 0.0 0.0074 15.6 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.6 CDJ97523.1 - 0.0071 16.6 0.0 0.0095 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CDJ97523.1 - 0.0099 15.4 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.6 CDJ97523.1 - 0.011 16.1 0.0 0.018 15.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CDJ97523.1 - 0.029 14.7 0.0 0.034 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CDJ97523.1 - 0.039 13.6 0.0 0.049 13.2 0.0 1.1 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ADK PF00406.22 CDJ97523.1 - 0.086 12.9 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Adenylate kinase Mg_chelatase PF01078.21 CDJ97523.1 - 0.11 11.9 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 CDJ97523.1 - 0.15 12.5 0.0 0.2 12.1 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ADK PF00406.22 CDJ97524.1 - 1.2e-05 25.4 0.1 1.2e-05 25.4 0.1 1.0 1 0 0 1 1 1 1 Adenylate kinase UIM PF02809.20 CDJ97525.1 - 0.0068 16.3 12.6 0.03 14.2 2.6 2.5 2 0 0 2 2 2 2 Ubiquitin interaction motif DUF3913 PF13052.6 CDJ97526.1 - 0.16 12.3 0.1 1.6 9.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3913) XhlA PF10779.9 CDJ97527.1 - 0.073 13.3 7.1 0.45 10.8 1.4 2.8 1 1 1 2 2 2 0 Haemolysin XhlA SecD-TM1 PF13721.6 CDJ97527.1 - 3.2 8.2 8.0 1.3 9.6 1.3 2.6 2 1 0 2 2 2 0 SecD export protein N-terminal TM region VWA PF00092.28 CDJ97528.1 - 1e-27 97.5 0.3 1.9e-27 96.7 0.1 1.4 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 CDJ97528.1 - 1.7e-15 57.6 0.4 2.3e-15 57.2 0.4 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain NFACT-C PF11923.8 CDJ97528.1 - 0.15 11.9 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 NFACT protein C-terminal domain Peptidase_S28 PF05577.12 CDJ97529.1 - 3.4e-237 787.3 1.1 1.3e-129 432.8 0.5 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 CDJ97529.1 - 3.7e-07 30.0 0.0 0.027 14.1 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2920 PF11144.8 CDJ97529.1 - 0.019 14.1 0.1 0.56 9.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Peptidase_S9 PF00326.21 CDJ97529.1 - 0.023 14.2 0.0 0.26 10.7 0.0 2.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family Osmo_CC PF08946.10 CDJ97529.1 - 0.48 10.7 2.2 1.3 9.3 0.2 2.6 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Peptidase_S28 PF05577.12 CDJ97530.1 - 8.3e-241 799.2 3.8 4.9e-126 421.0 1.8 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 CDJ97530.1 - 5.1e-13 49.2 0.0 2.6e-05 24.0 0.0 3.2 3 0 0 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ97530.1 - 1.4e-11 44.1 0.0 2.8e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CDJ97530.1 - 1.5e-05 24.6 0.8 0.002 17.7 0.0 3.9 4 0 0 4 4 4 1 Prolyl oligopeptidase family Esterase PF00756.20 CDJ97530.1 - 2e-05 24.3 0.0 0.00047 19.9 0.0 2.3 2 0 0 2 2 2 1 Putative esterase DUF2920 PF11144.8 CDJ97530.1 - 0.0015 17.8 0.1 1.7 7.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2920) CLIP1_ZNF PF16641.5 CDJ97530.1 - 0.55 10.2 2.1 3.4 7.6 0.3 2.7 2 0 0 2 2 2 0 CLIP1 zinc knuckle Peptidase_S28 PF05577.12 CDJ97531.1 - 4.3e-184 612.3 0.3 1.5e-131 439.2 0.4 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 CDJ97531.1 - 0.00069 18.9 0.0 0.039 13.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ97531.1 - 0.00083 19.1 0.0 0.0038 16.9 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2920 PF11144.8 CDJ97531.1 - 0.0065 15.7 0.0 0.022 13.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2920) Atg14 PF10186.9 CDJ97532.1 - 0.19 10.8 2.0 0.27 10.3 2.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 EGF_3 PF12947.7 CDJ97533.1 - 4.5e-66 218.7 262.6 7.1e-08 32.5 5.9 22.4 22 0 0 22 22 22 18 EGF domain EGF_CA PF07645.15 CDJ97533.1 - 4.6e-65 215.6 287.8 1.5e-06 28.3 4.9 22.4 22 0 0 22 22 22 18 Calcium-binding EGF domain EGF PF00008.27 CDJ97533.1 - 2.3e-50 168.5 252.0 7.5e-06 26.1 4.8 23.2 22 1 0 22 22 22 18 EGF-like domain VWA PF00092.28 CDJ97533.1 - 2.9e-43 148.1 0.4 4.3e-43 147.6 0.4 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain hEGF PF12661.7 CDJ97533.1 - 1.2e-42 143.1 220.3 0.0001 22.7 0.9 23.8 23 0 0 23 23 22 20 Human growth factor-like EGF VWA_2 PF13519.6 CDJ97533.1 - 3.1e-15 56.7 0.0 5.6e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain FXa_inhibition PF14670.6 CDJ97533.1 - 7.4e-11 42.2 273.6 0.039 14.2 1.5 22.6 22 0 0 22 22 22 17 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 CDJ97533.1 - 1.9e-07 31.0 217.9 0.00087 19.3 4.5 21.0 21 0 0 21 21 20 13 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 CDJ97533.1 - 4.6e-06 26.8 247.1 0.0012 19.2 7.0 22.2 21 2 1 22 22 21 13 Pvs28 EGF domain SEA PF01390.20 CDJ97533.1 - 0.027 14.5 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 SEA domain ClpB_D2-small PF10431.9 CDJ97533.1 - 0.073 13.1 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein cEGF PF12662.7 CDJ97533.1 - 0.64 10.0 172.3 0.14 12.2 1.1 22.0 22 0 0 22 22 21 0 Complement Clr-like EGF-like Rtt106_N PF18215.1 CDJ97534.1 - 0.02 14.7 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Histone chaperone Rtt106 N-terminal domain SAM_2 PF07647.17 CDJ97534.1 - 0.023 14.8 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) tRNA-synt_1 PF00133.22 CDJ97537.1 - 2.1e-36 125.4 0.0 2.1e-22 79.1 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDJ97537.1 - 2.5e-16 60.0 0.3 7.9e-16 58.4 0.3 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CDJ97537.1 - 2.7e-15 56.1 0.0 5.9e-07 28.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CDJ97537.1 - 3.2e-05 23.4 0.0 9.2e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF1679 PF07914.11 CDJ97538.1 - 4.6e-12 45.5 0.0 4.8e-12 45.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) DUF1679 PF07914.11 CDJ97539.1 - 4.7e-49 167.4 0.0 5.4e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 CDJ97539.1 - 3.9e-16 59.2 0.0 5.3e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 CDJ97539.1 - 4.1e-11 43.3 0.3 4.9e-11 43.0 0.3 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDJ97539.1 - 4.8e-05 23.1 0.1 6.6e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 CDJ97539.1 - 0.0052 16.2 1.2 0.0085 15.5 1.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 CDJ97540.1 - 1.9e-35 122.6 2.3 2e-35 122.4 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) DUF2202 PF09968.9 CDJ97540.1 - 0.0018 18.1 0.7 0.13 12.1 0.3 2.1 1 1 1 2 2 2 2 Uncharacterized protein domain (DUF2202) PB1-F2 PF11986.8 CDJ97540.1 - 0.083 13.1 0.5 0.22 11.8 0.2 1.8 1 1 1 2 2 2 0 Influenza A Proapoptotic protein DUF3676 PF12429.8 CDJ97541.1 - 0.00077 19.4 1.3 0.00095 19.1 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3676) RVT_1 PF00078.27 CDJ97543.1 - 1.4e-29 103.2 0.0 2.2e-29 102.6 0.0 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CDJ97545.1 - 9.2e-07 28.6 0.0 1.9e-06 27.5 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4423 PF14394.6 CDJ97546.1 - 0.046 13.4 0.9 0.088 12.5 0.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4423) Cep57_CLD_2 PF14197.6 CDJ97546.1 - 1.1 9.4 6.8 1.7 8.8 6.0 1.8 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 ODV-E18 PF10717.9 CDJ97547.1 - 0.0053 16.6 0.1 0.0053 16.6 0.1 2.3 1 1 0 2 2 2 1 Occlusion-derived virus envelope protein ODV-E18 Cytochrom_C552 PF02335.15 CDJ97547.1 - 0.032 13.2 0.3 0.037 13.0 0.3 1.0 1 0 0 1 1 1 0 Cytochrome c552 7TM_GPCR_Sru PF10322.9 CDJ97547.1 - 0.064 12.6 5.2 0.084 12.2 5.2 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru RSN1_TM PF13967.6 CDJ97547.1 - 0.07 12.9 0.2 0.1 12.3 0.2 1.2 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Shisa PF13908.6 CDJ97547.1 - 0.39 10.9 5.4 0.11 12.7 1.7 1.8 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator FAM199X PF15814.5 CDJ97547.1 - 0.7 8.9 12.3 0.89 8.6 12.3 1.2 1 0 0 1 1 1 0 Protein family FAM199X TSP_1 PF00090.19 CDJ97548.1 - 0.0023 18.1 5.2 0.0023 18.1 5.2 3.9 4 0 0 4 4 4 3 Thrombospondin type 1 domain CCDC-167 PF15188.6 CDJ97548.1 - 0.047 14.0 2.3 0.13 12.7 2.3 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Rotamase PF00639.21 CDJ97548.1 - 1.4 9.9 4.3 0.36 11.8 0.5 2.0 2 0 0 2 2 2 0 PPIC-type PPIASE domain Myosin_head PF00063.21 CDJ97549.1 - 1.1e-235 784.0 0.0 1.2e-235 783.8 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 CDJ97549.1 - 2.5e-06 27.2 0.2 4.8e-06 26.3 0.2 1.4 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 CDJ97549.1 - 0.0021 18.4 0.0 0.007 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDJ97549.1 - 0.036 14.3 0.0 0.25 11.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRP19 PF01922.17 CDJ97550.1 - 1e-13 52.0 0.0 1.5e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 SRP19 protein Flg_hook PF02120.16 CDJ97550.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Ctr PF04145.15 CDJ97551.1 - 7.4e-49 166.2 26.2 4.5e-25 89.0 1.0 3.2 2 1 1 3 3 3 3 Ctr copper transporter family DUF998 PF06197.13 CDJ97551.1 - 0.064 12.8 0.0 0.064 12.8 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF998) FXR_C1 PF16096.5 CDJ97552.1 - 8.3 6.7 8.3 5.3 7.3 3.6 2.9 2 1 1 3 3 3 0 Fragile X-related 1 protein C-terminal region 2 BRK PF07533.16 CDJ97554.1 - 4.3e-23 80.7 0.2 4.5e-12 45.4 0.1 2.8 2 0 0 2 2 2 2 BRK domain Chromo PF00385.24 CDJ97554.1 - 6.1e-20 70.9 6.2 4.1e-09 36.2 0.2 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 CDJ97554.1 - 6.2e-19 68.4 0.1 2e-18 66.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 CDJ97554.1 - 7.3e-19 67.7 2.3 7.3e-19 67.7 2.3 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain HDA2-3 PF11496.8 CDJ97554.1 - 0.0001 21.6 2.7 0.00019 20.7 0.3 2.3 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 MobB PF03205.14 CDJ97554.1 - 0.012 15.5 0.1 3.6 7.5 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Patched PF02460.18 CDJ97555.1 - 1.5e-13 49.8 0.6 2.5e-13 49.1 0.6 1.3 1 0 0 1 1 1 1 Patched family RRM_1 PF00076.22 CDJ97556.1 - 3.7e-13 49.1 0.0 5.2e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CDJ97556.1 - 0.07 13.2 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif RL PF17797.1 CDJ97556.1 - 0.079 12.9 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 RL domain CIA30 PF08547.12 CDJ97557.1 - 8.2e-37 126.7 0.2 2.4e-36 125.2 0.1 1.7 2 0 0 2 2 2 1 Complex I intermediate-associated protein 30 (CIA30) S1FA PF04689.13 CDJ97559.1 - 0.0049 17.0 1.4 0.01 16.0 1.4 1.5 1 0 0 1 1 1 1 DNA binding protein S1FA OAD_gamma PF04277.13 CDJ97559.1 - 0.15 12.7 5.2 0.54 10.9 5.2 2.0 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain FAM176 PF14851.6 CDJ97559.1 - 2.8 7.6 5.1 2.7 7.6 0.0 2.5 2 1 0 2 2 2 0 FAM176 family PGAP1 PF07819.13 CDJ97560.1 - 6.5e-51 173.3 0.0 1.1e-50 172.5 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein HLH PF00010.26 CDJ97560.1 - 1e-12 47.8 2.5 1.9e-12 46.9 2.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Abhydrolase_6 PF12697.7 CDJ97560.1 - 3.1e-05 24.7 0.1 6.6e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family DivIC PF04977.15 CDJ97560.1 - 0.0032 17.2 3.4 0.0047 16.7 2.4 1.8 1 1 0 1 1 1 1 Septum formation initiator DUF915 PF06028.11 CDJ97560.1 - 0.0055 16.1 0.1 0.49 9.7 0.0 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF4391 PF14335.6 CDJ97560.1 - 0.05 13.3 0.4 0.085 12.6 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) PAF-AH_p_II PF03403.13 CDJ97560.1 - 0.096 11.2 0.0 0.2 10.1 0.0 1.5 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II OmpH PF03938.14 CDJ97560.1 - 0.34 11.2 4.1 0.67 10.3 4.1 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Phage_holin_5_2 PF16079.5 CDJ97560.1 - 0.73 10.2 5.2 0.33 11.3 0.4 2.6 1 1 1 2 2 2 0 Phage holin family Hol44, in holin superfamily V Atg14 PF10186.9 CDJ97560.1 - 1.8 7.6 5.4 4.8 6.2 5.6 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4200 PF13863.6 CDJ97560.1 - 2.1 8.8 8.1 4.3 7.8 8.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Thioredoxin_6 PF13848.6 CDJ97561.1 - 4.7e-08 33.2 0.5 0.016 15.2 0.0 4.3 4 0 0 4 4 4 3 Thioredoxin-like domain Thioredoxin PF00085.20 CDJ97561.1 - 2.5e-07 30.6 0.0 0.0021 18.0 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin ATP-synt_B PF00430.18 CDJ97561.1 - 0.083 13.0 1.5 0.18 11.9 1.5 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) CaMBD PF02888.16 CDJ97561.1 - 0.3 11.3 2.2 1.1 9.5 2.2 2.0 1 0 0 1 1 1 0 Calmodulin binding domain TPR_2 PF07719.17 CDJ97562.1 - 4e-05 23.4 0.7 0.004 17.2 0.7 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ97562.1 - 0.00082 20.0 0.7 0.22 12.4 0.5 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ97562.1 - 0.0029 18.1 0.1 0.0079 16.7 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TackOD1 PF18551.1 CDJ97562.1 - 0.0055 16.4 0.6 0.011 15.4 0.2 1.6 1 1 0 1 1 1 1 Thaumarchaeal output domain 1 TPR_10 PF13374.6 CDJ97562.1 - 0.012 15.5 0.1 0.037 13.9 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ97562.1 - 0.035 14.4 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ97562.1 - 0.037 14.2 0.4 0.092 13.0 0.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CDJ97562.1 - 0.038 13.7 0.0 0.53 10.0 0.2 2.4 2 0 0 2 2 2 0 TPR repeat TPR_8 PF13181.6 CDJ97562.1 - 0.048 13.9 0.3 0.34 11.2 0.5 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat RRM_1 PF00076.22 CDJ97564.1 - 4.1e-25 87.4 0.1 4.7e-25 87.2 0.1 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ97564.1 - 0.00015 21.5 0.0 0.00031 20.5 0.0 1.5 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_7 PF16367.5 CDJ97564.1 - 0.0038 17.3 0.0 0.011 15.9 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif BRAP2 PF07576.12 CDJ97564.1 - 0.0053 16.9 0.0 0.0065 16.7 0.0 1.1 1 0 0 1 1 1 1 BRCA1-associated protein 2 PHM7_cyt PF14703.6 CDJ97564.1 - 0.05 13.8 0.0 8.4 6.6 0.0 2.0 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.6 CDJ97564.1 - 0.074 12.7 0.0 0.084 12.5 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 CDJ97564.1 - 0.097 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 DbpA RNA binding domain Metallophos PF00149.28 CDJ97566.1 - 9.3e-17 62.2 4.6 1.2e-16 61.8 4.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDJ97566.1 - 7.6e-09 36.0 0.8 6.4e-08 33.0 0.8 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MutL PF13941.6 CDJ97566.1 - 0.12 11.0 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 MutL protein DUF1460 PF07313.12 CDJ97566.1 - 0.14 11.6 0.1 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) Dus PF01207.17 CDJ97566.1 - 0.2 10.7 0.0 0.34 10.0 0.0 1.3 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) DUF2207 PF09972.9 CDJ97567.1 - 0.0036 16.1 0.0 0.0041 16.0 0.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) MGC-24 PF05283.11 CDJ97567.1 - 0.0061 17.0 0.0 0.0077 16.7 0.0 1.2 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF5305 PF17231.2 CDJ97567.1 - 0.015 14.8 0.0 0.018 14.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) TMEM154 PF15102.6 CDJ97567.1 - 0.015 15.2 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 CDJ97567.1 - 0.019 15.8 0.0 0.05 14.5 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF1180 PF06679.12 CDJ97567.1 - 0.023 15.1 0.0 0.03 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Orf78 PF06024.12 CDJ97567.1 - 0.024 14.9 0.0 0.031 14.6 0.0 1.1 1 0 0 1 1 1 0 Orf78 (ac78) TRP PF06011.12 CDJ97567.1 - 0.054 12.2 0.0 0.06 12.1 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel CD34_antigen PF06365.12 CDJ97567.1 - 0.075 12.6 0.0 0.09 12.3 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF4083 PF13314.6 CDJ97567.1 - 0.08 12.9 2.5 0.15 12.0 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) UL42 PF17638.2 CDJ97567.1 - 0.087 12.8 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 HCMV UL42 Amnionless PF14828.6 CDJ97567.1 - 0.1 11.4 0.0 0.12 11.2 0.0 1.0 1 0 0 1 1 1 0 Amnionless Sigma_reg_N PF13800.6 CDJ97567.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal CRPA PF05745.11 CDJ97567.1 - 0.12 12.3 1.2 0.19 11.7 1.2 1.3 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF2621 PF11084.8 CDJ97567.1 - 0.18 11.8 0.0 0.22 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) Peptidase_U4 PF03419.13 CDJ97568.1 - 0.22 10.8 6.2 0.28 10.4 6.2 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF202 PF02656.15 CDJ97568.1 - 1.5 9.3 6.9 0.52 10.8 2.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Alpha_L_fucos PF01120.17 CDJ97569.1 - 6e-107 358.1 7.9 8.7e-107 357.6 7.9 1.2 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 CDJ97569.1 - 0.00012 22.5 0.6 0.00067 20.2 0.6 2.2 1 1 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain PROCT PF08084.11 CDJ97569.1 - 0.037 14.0 0.1 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 PROCT (NUC072) domain Luciferase_N PF05295.11 CDJ97569.1 - 0.069 13.2 0.0 0.18 11.9 0.0 1.7 1 1 0 1 1 1 0 Luciferase/LBP N-terminal domain Peptidase_M13 PF01431.21 CDJ97570.1 - 6.4e-80 267.6 6.2 1.7e-79 266.2 0.7 2.6 3 0 0 3 3 3 2 Peptidase family M13 Peptidase_M13_N PF05649.13 CDJ97570.1 - 1.4e-63 215.9 1.7 2.1e-63 215.3 1.7 1.3 1 0 0 1 1 1 1 Peptidase family M13 MpPF26 PF07666.11 CDJ97570.1 - 0.045 13.9 0.1 0.092 12.9 0.1 1.4 1 0 0 1 1 1 0 M penetrans paralogue family 26 Clc-like PF07062.12 CDJ97571.1 - 0.019 14.5 0.0 0.024 14.1 0.0 1.1 1 0 0 1 1 1 0 Clc-like DUF4692 PF15763.5 CDJ97571.1 - 0.045 14.2 0.0 0.09 13.3 0.0 1.5 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) DUF5480 PF17576.2 CDJ97571.1 - 0.059 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5480) Chordopox_A33R PF05966.12 CDJ97571.1 - 0.096 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus A33R protein DUF3149 PF11346.8 CDJ97571.1 - 0.11 12.1 1.1 0.16 11.6 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) UL42 PF17638.2 CDJ97571.1 - 0.12 12.3 0.2 0.22 11.5 0.2 1.5 1 0 0 1 1 1 0 HCMV UL42 TMEM154 PF15102.6 CDJ97571.1 - 0.6 10.0 2.7 0.87 9.5 0.1 1.9 2 0 0 2 2 2 0 TMEM154 protein family CAP PF00188.26 CDJ97572.1 - 2.5e-10 41.3 4.3 3.3e-10 40.9 4.3 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TUSC2 PF15000.6 CDJ97573.1 - 4.2e-27 94.7 0.1 5e-27 94.4 0.1 1.1 1 0 0 1 1 1 1 Tumour suppressor candidate 2 Pyridoxal_deC PF00282.19 CDJ97574.1 - 1.2e-20 73.6 0.0 1.8e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CDJ97574.1 - 6.8e-07 28.6 0.0 1.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CDJ97574.1 - 9.8e-07 28.3 0.0 1.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CDJ97574.1 - 8.5e-05 22.0 0.1 0.00014 21.3 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 CDJ97574.1 - 0.088 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Med20 PF08612.11 CDJ97575.1 - 1.5e-29 103.0 0.0 1.7e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex T6SS_TssF PF05947.12 CDJ97575.1 - 0.072 11.6 0.1 0.11 11.0 0.1 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssF SH3_2 PF07653.17 CDJ97576.1 - 0.12 12.0 0.0 1.8 8.3 0.0 2.7 3 0 0 3 3 3 0 Variant SH3 domain ECH_1 PF00378.20 CDJ97577.1 - 1.5e-39 135.9 0.0 2.5e-26 92.5 0.0 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CDJ97577.1 - 2.2e-18 66.9 0.0 2.5e-14 53.5 0.0 2.6 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase NUDIX PF00293.28 CDJ97577.1 - 0.0089 16.1 0.0 0.045 13.8 0.0 2.1 2 0 0 2 2 2 1 NUDIX domain DUF1086 PF06461.11 CDJ97577.1 - 0.02 14.8 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) GRAM PF02893.20 CDJ97578.1 - 5.7e-06 26.2 0.0 1.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 GRAM domain PRT_C PF08372.10 CDJ97578.1 - 6.9e-05 22.6 0.8 6.9e-05 22.6 0.8 1.8 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal Pex24p PF06398.11 CDJ97578.1 - 0.00093 18.3 4.8 0.26 10.2 1.9 2.3 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin Endonuc-MspI PF09208.10 CDJ97578.1 - 0.084 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease MspI DUF639 PF04842.12 CDJ97578.1 - 0.19 11.1 2.1 0.17 11.3 0.2 1.8 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) Reticulon PF02453.17 CDJ97578.1 - 4.3 7.3 13.3 8.9 6.3 2.1 2.1 1 1 1 2 2 2 0 Reticulon Leo1 PF04004.13 CDJ97579.1 - 4.1e-49 166.6 0.3 9.6e-49 165.4 0.3 1.7 1 0 0 1 1 1 1 Leo1-like protein AFT PF08731.11 CDJ97579.1 - 0.13 12.7 0.1 0.13 12.7 0.1 3.1 4 0 0 4 4 4 0 Transcription factor AFT Pkinase PF00069.25 CDJ97580.1 - 2.1e-71 240.4 0.0 3.1e-71 239.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain POLO_box PF00659.18 CDJ97580.1 - 2.4e-41 139.7 0.5 2.3e-21 75.8 0.1 2.6 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_Tyr PF07714.17 CDJ97580.1 - 6e-41 140.4 0.0 1.3e-40 139.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ97580.1 - 1.1e-09 38.1 0.0 2.7e-08 33.5 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CDJ97580.1 - 3.6e-05 22.7 0.0 5.8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDJ97580.1 - 0.08 12.3 0.1 0.24 10.8 0.1 1.8 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GatB_N PF02934.15 CDJ97583.1 - 4.1e-100 334.7 0.0 5.4e-100 334.3 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 CDJ97583.1 - 4.4e-12 46.1 0.5 6.6e-12 45.5 0.5 1.2 1 0 0 1 1 1 1 GatB domain HEAT PF02985.22 CDJ97584.1 - 4.9e-39 129.0 31.7 0.00028 20.9 0.0 20.1 21 0 0 21 21 20 7 HEAT repeat Cnd1 PF12717.7 CDJ97584.1 - 9.3e-26 90.8 14.9 0.00016 21.7 0.0 12.0 10 2 2 12 12 12 5 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDJ97584.1 - 5.4e-24 84.4 50.9 2.6e-05 24.5 0.0 17.4 13 6 5 18 18 18 3 HEAT repeats CLASP_N PF12348.8 CDJ97584.1 - 1.3e-22 80.5 5.0 0.00011 21.9 0.0 7.6 6 1 2 8 8 8 6 CLASP N terminal HEAT_EZ PF13513.6 CDJ97584.1 - 1.8e-20 73.0 30.4 0.025 15.1 0.1 15.7 13 3 2 15 15 15 7 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CDJ97584.1 - 3.3e-17 62.9 0.0 0.059 14.0 0.0 8.4 6 3 1 8 8 7 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 CDJ97584.1 - 7.5e-15 54.5 16.4 0.0013 17.4 0.0 8.6 6 2 0 7 7 7 4 Adaptin N terminal region MMS19_C PF12460.8 CDJ97584.1 - 2.2e-06 27.1 22.0 0.013 14.6 0.1 7.9 7 1 0 7 7 7 3 RNAPII transcription regulator C-terminal UME PF08064.13 CDJ97584.1 - 1e-05 25.4 2.3 2.3 8.2 0.0 8.1 8 3 1 9 9 9 1 UME (NUC010) domain Tti2 PF10521.9 CDJ97584.1 - 2.6e-05 23.9 0.3 1.6 8.2 0.0 5.2 3 2 1 4 4 4 2 Tti2 family DUF3385 PF11865.8 CDJ97584.1 - 4e-05 23.6 0.0 4.3 7.2 0.0 5.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) RTP1_C1 PF10363.9 CDJ97584.1 - 4.3e-05 23.7 4.9 4.8 7.4 0.1 7.3 6 1 0 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 ParcG PF10274.9 CDJ97584.1 - 0.0037 17.4 4.8 0.24 11.5 0.0 5.4 6 0 0 6 6 6 1 Parkin co-regulated protein NUC173 PF08161.12 CDJ97584.1 - 0.014 15.1 2.2 0.71 9.5 0.1 4.1 3 0 0 3 3 3 0 NUC173 domain RIX1 PF08167.12 CDJ97584.1 - 0.025 14.3 7.6 9.3 5.9 0.1 6.9 8 0 0 8 8 8 0 rRNA processing/ribosome biogenesis NopRA1 PF16201.5 CDJ97584.1 - 0.054 13.1 6.8 0.39 10.3 0.1 5.3 5 1 0 6 6 6 0 Nucleolar pre-ribosomal-associated protein 1 Dopey_N PF04118.14 CDJ97584.1 - 0.059 12.5 1.8 2.1 7.4 0.0 3.6 3 1 1 4 4 4 0 Dopey, N-terminal Cohesin_HEAT PF12765.7 CDJ97584.1 - 0.17 12.2 0.5 10 6.5 0.1 4.3 3 0 0 3 3 2 0 HEAT repeat associated with sister chromatid cohesion Condensin2nSMC PF12422.8 CDJ97584.1 - 0.21 11.8 2.5 80 3.4 0.0 5.6 4 1 0 4 4 4 0 Condensin II non structural maintenance of chromosomes subunit Arm PF00514.23 CDJ97584.1 - 0.66 10.1 7.2 1.1e+02 3.0 0.0 7.2 7 0 0 7 7 6 0 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.14 CDJ97584.1 - 1.7 7.9 10.1 2.6 7.3 0.0 5.2 6 0 0 6 6 6 0 V-ATPase subunit H DUF4337 PF14235.6 CDJ97584.1 - 9.8 6.3 16.9 10 6.2 4.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Alpha_kinase PF02816.18 CDJ97586.1 - 0.066 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha-kinase family Histone PF00125.24 CDJ97587.1 - 7.6e-54 181.6 1.6 8.5e-54 181.4 1.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CDJ97587.1 - 7.9e-05 22.7 0.2 0.00017 21.7 0.0 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CDJ97587.1 - 0.00015 22.3 2.4 0.00019 22.0 2.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 CDJ97587.1 - 0.00028 21.2 0.0 0.00042 20.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CDJ97587.1 - 0.054 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MscS_porin PF12795.7 CDJ97588.1 - 0.00074 19.1 5.6 0.00087 18.9 5.6 1.0 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain V-SNARE PF05008.15 CDJ97588.1 - 0.00086 19.6 4.1 0.0013 19.1 4.1 1.3 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus DUF4200 PF13863.6 CDJ97588.1 - 0.0018 18.7 4.6 0.0022 18.4 4.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) Spc7 PF08317.11 CDJ97588.1 - 0.0025 16.8 4.1 0.0027 16.6 4.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein SlyX PF04102.12 CDJ97588.1 - 0.0039 17.8 3.1 0.0055 17.3 3.1 1.3 1 0 0 1 1 1 1 SlyX Filament PF00038.21 CDJ97588.1 - 0.0079 15.8 4.6 0.0088 15.7 4.6 1.0 1 0 0 1 1 1 1 Intermediate filament protein DUF641 PF04859.12 CDJ97588.1 - 0.01 16.2 2.1 0.012 15.9 2.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Arm-DNA-bind_5 PF17293.2 CDJ97588.1 - 0.011 16.2 0.3 0.014 15.8 0.3 1.2 1 0 0 1 1 1 0 Arm DNA-binding domain APG6_N PF17675.1 CDJ97588.1 - 0.011 16.2 3.2 0.013 16.0 3.2 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region Prominin PF05478.11 CDJ97588.1 - 0.012 13.6 1.2 0.013 13.5 1.2 1.0 1 0 0 1 1 1 0 Prominin Herpes_UL6 PF01763.16 CDJ97588.1 - 0.014 14.0 1.5 0.015 13.9 1.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like RILP PF11461.8 CDJ97588.1 - 0.023 14.9 6.5 0.074 13.3 5.9 2.0 1 1 1 2 2 2 0 Rab interacting lysosomal protein Laminin_II PF06009.12 CDJ97588.1 - 0.028 14.5 2.8 0.031 14.3 2.8 1.1 1 0 0 1 1 1 0 Laminin Domain II Syntaxin_2 PF14523.6 CDJ97588.1 - 0.045 14.1 5.6 0.081 13.3 5.6 1.4 1 1 0 1 1 1 0 Syntaxin-like protein DivIC PF04977.15 CDJ97588.1 - 0.046 13.5 3.2 0.063 13.1 3.2 1.2 1 0 0 1 1 1 0 Septum formation initiator UPF0242 PF06785.11 CDJ97588.1 - 0.053 13.6 4.4 0.059 13.5 4.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HR1 PF02185.16 CDJ97588.1 - 0.059 13.5 11.0 1.2 9.3 11.0 2.3 1 1 0 1 1 1 0 Hr1 repeat CREPT PF16566.5 CDJ97588.1 - 0.079 13.1 4.2 0.096 12.9 4.2 1.1 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour NPV_P10 PF05531.12 CDJ97588.1 - 0.087 13.3 2.8 0.38 11.2 2.8 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein USP8_interact PF08941.10 CDJ97588.1 - 0.21 11.4 3.3 0.27 11.0 3.3 1.1 1 0 0 1 1 1 0 USP8 interacting Spc24 PF08286.11 CDJ97588.1 - 0.34 11.2 5.3 0.64 10.3 4.9 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 AAA_lid_3 PF17862.1 CDJ97589.1 - 3.6e-12 45.9 0.1 5.7e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 CDJ97589.1 - 1.8e-10 41.4 0.3 6.6e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Nuc_deoxyrib_tr PF05014.15 CDJ97589.1 - 0.055 13.5 0.1 0.075 13.0 0.1 1.1 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase Rad60-SLD_2 PF13881.6 CDJ97590.1 - 3.7e-42 142.9 0.3 1.1e-25 89.9 0.0 2.0 1 1 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CDJ97590.1 - 1.1e-10 41.1 0.1 0.00032 20.4 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin family DUF2407 PF10302.9 CDJ97590.1 - 7.1e-05 23.3 0.0 0.51 10.9 0.0 2.5 3 0 0 3 3 3 2 DUF2407 ubiquitin-like domain DUF1153 PF06627.11 CDJ97590.1 - 0.062 13.4 0.8 6.4 7.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1153) GbpA_2 PF18416.1 CDJ97590.1 - 0.091 13.1 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 N-acetylglucosamine binding protein domain 2 Helicase_C_2 PF13307.6 CDJ97591.1 - 1.6e-50 171.6 0.1 6.1e-50 169.7 0.1 2.1 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 CDJ97591.1 - 1.3e-39 135.6 0.3 2.8e-39 134.5 0.3 1.6 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.29 CDJ97591.1 - 0.0094 15.7 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ97591.1 - 0.018 15.0 0.0 0.28 11.1 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit HBD PF18534.1 CDJ97591.1 - 0.022 14.9 4.6 0.51 10.5 1.0 3.1 2 1 1 3 3 3 0 Helical bundle domain RRP7 PF12923.7 CDJ97591.1 - 0.033 14.3 1.3 0.089 12.9 1.3 1.7 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Nup54_C PF18437.1 CDJ97591.1 - 0.042 13.7 1.0 0.1 12.5 1.0 1.7 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain MM_CoA_mutase PF01642.22 CDJ97592.1 - 4.9e-199 662.1 6.8 2.1e-138 462.1 5.8 2.2 1 1 1 2 2 2 2 Methylmalonyl-CoA mutase B12-binding PF02310.19 CDJ97592.1 - 3.4e-14 52.9 0.3 1e-13 51.4 0.3 1.8 1 0 0 1 1 1 1 B12 binding domain FXa_inhibition PF14670.6 CDJ97593.1 - 2.8e-81 267.5 183.1 2.4e-11 43.7 12.9 11.1 11 0 0 11 11 11 9 Coagulation Factor Xa inhibitory site cEGF PF12662.7 CDJ97593.1 - 1.6e-54 181.4 95.7 2.3e-08 33.8 3.0 11.7 12 0 0 12 12 12 10 Complement Clr-like EGF-like EGF_CA PF07645.15 CDJ97593.1 - 1e-34 118.4 166.8 3.7e-08 33.4 8.3 11.2 11 0 0 11 11 11 8 Calcium-binding EGF domain EGF PF00008.27 CDJ97593.1 - 2e-23 82.3 153.2 0.00019 21.7 9.3 12.2 11 1 0 11 11 11 9 EGF-like domain EMI PF07546.13 CDJ97593.1 - 8.3e-10 39.3 11.4 8.3e-10 39.3 11.4 4.0 3 1 0 3 3 3 1 EMI domain EGF_3 PF12947.7 CDJ97593.1 - 1.5e-08 34.7 159.8 9.9e-05 22.5 8.8 11.3 10 1 0 10 10 10 6 EGF domain hEGF PF12661.7 CDJ97593.1 - 0.00024 21.6 14.6 0.0022 18.6 6.2 13.1 13 0 0 13 13 13 4 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CDJ97593.1 - 0.017 15.1 2.9 0.017 15.1 2.9 11.1 11 0 0 11 11 11 0 MSP1 EGF domain 1 Laminin_EGF PF00053.24 CDJ97594.1 - 3.4e-50 168.0 287.5 0.0017 18.5 9.5 17.3 5 5 12 17 17 17 15 Laminin EGF domain hEGF PF12661.7 CDJ97594.1 - 6.3e-07 29.8 56.9 0.0015 19.1 5.8 22.7 22 2 1 23 23 23 13 Human growth factor-like EGF EGF_2 PF07974.13 CDJ97594.1 - 1.1e-05 25.7 23.0 7.8e-05 23.0 11.0 28.7 24 9 2 26 26 26 11 EGF-like domain EGF PF00008.27 CDJ97594.1 - 0.0041 17.4 26.9 0.0067 16.7 9.0 24.4 24 4 0 24 24 24 11 EGF-like domain TPR_4 PF07721.14 CDJ97595.1 - 0.0054 17.2 2.8 11 7.0 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ97595.1 - 0.016 15.3 11.4 2.1 8.7 0.2 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ97595.1 - 0.55 10.2 9.4 11 6.0 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 CDJ97596.1 - 0.0064 15.7 0.1 0.012 14.8 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ97596.1 - 0.039 14.8 2.4 21 6.3 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TF_AP-2 PF03299.14 CDJ97596.1 - 0.058 13.4 0.6 0.29 11.1 0.0 2.1 2 0 0 2 2 2 0 Transcription factor AP-2 TPR_12 PF13424.6 CDJ97596.1 - 0.42 10.9 2.6 6.7 7.1 0.3 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ97596.1 - 4.6 7.6 11.4 2 8.7 0.8 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Sulfotransfer_2 PF03567.14 CDJ97597.1 - 8.5e-24 84.8 7.0 1.1e-23 84.5 7.0 1.0 1 0 0 1 1 1 1 Sulfotransferase family KIX_2 PF16987.5 CDJ97597.1 - 0.0028 17.6 0.5 0.012 15.6 0.1 2.1 2 0 0 2 2 2 1 KIX domain Lipoprotein_18 PF06804.11 CDJ97598.1 - 0.00043 19.4 2.4 0.00047 19.3 0.9 1.7 1 1 0 1 1 1 1 NlpB/DapX lipoprotein Glyco_hydro_67N PF03648.14 CDJ97598.1 - 0.03 14.6 0.7 0.07 13.4 0.7 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus DivIC PF04977.15 CDJ97598.1 - 0.59 9.9 3.5 1.5 8.6 3.5 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF4407 PF14362.6 CDJ97598.1 - 1 8.7 4.8 0.28 10.5 1.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Dna2 PF08696.11 CDJ97598.1 - 1.1 9.0 5.7 0.24 11.2 0.6 2.1 2 0 0 2 2 2 0 DNA replication factor Dna2 DnaJ PF00226.31 CDJ97600.1 - 3.1e-23 81.7 1.4 3.1e-23 81.7 1.4 2.1 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 CDJ97600.1 - 1.6e-10 41.0 3.3 1.6e-10 41.0 3.3 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CDJ97600.1 - 3.2e-05 24.2 13.0 0.16 12.3 0.0 3.6 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CDJ97600.1 - 0.00055 20.2 2.4 0.0017 18.7 2.4 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CDJ97600.1 - 0.065 13.7 14.2 0.38 11.3 1.5 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ97600.1 - 0.39 11.7 14.8 0.6 11.1 0.9 4.0 5 0 0 5 5 5 0 C2H2-type zinc finger zf_ZIC PF18366.1 CDJ97600.1 - 1.6 8.9 4.6 2.2 8.4 0.3 3.0 3 0 0 3 3 3 0 Zic proteins zinc finger domain adh_short_C2 PF13561.6 CDJ97601.1 - 2.8e-07 30.3 0.0 3.7e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDJ97601.1 - 4.7e-06 26.2 0.1 1e-05 25.1 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 CDJ97601.1 - 0.00026 20.5 0.1 0.0014 18.1 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Melibiase_2 PF16499.5 CDJ97602.1 - 1.1e-81 274.1 1.5 1.2e-81 274.0 1.5 1.0 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase PF02065.18 CDJ97602.1 - 7.3e-05 21.9 0.0 0.00016 20.8 0.0 1.5 1 1 0 1 1 1 1 Melibiase COesterase PF00135.28 CDJ97603.1 - 9.5e-110 367.9 0.0 2.3e-108 363.3 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDJ97603.1 - 0.00085 19.2 0.0 0.002 18.1 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold USP8_dimer PF08969.11 CDJ97603.1 - 0.1 12.8 0.3 0.45 10.7 0.1 2.0 2 0 0 2 2 2 0 USP8 dimerisation domain COesterase PF00135.28 CDJ97604.1 - 4e-87 293.2 0.0 5.2e-87 292.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDJ97604.1 - 7.5e-07 29.2 0.4 2.3e-06 27.6 0.4 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CDJ97604.1 - 0.038 13.5 0.1 0.07 12.6 0.1 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 CDJ97604.1 - 0.22 10.3 0.0 1.4 7.7 0.0 1.8 2 0 0 2 2 2 0 Steryl acetyl hydrolase COesterase PF00135.28 CDJ97605.1 - 2.4e-26 92.7 0.0 2.6e-26 92.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family MqsR_toxin PF15723.5 CDJ97605.1 - 0.0017 18.7 0.1 3.1 8.2 0.0 2.4 2 0 0 2 2 2 2 Motility quorum-sensing regulator, toxin of MqsA DUF3052 PF11253.8 CDJ97605.1 - 0.028 14.3 0.2 0.05 13.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) dUTPase PF00692.19 CDJ97606.1 - 1.7e-39 134.4 0.0 2.3e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 dUTPase Sre PF03125.18 CDJ97607.1 - 7.8e-08 31.9 29.0 2.4e-05 23.7 29.0 2.1 1 1 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor 7TM_GPCR_Srab PF10292.9 CDJ97607.1 - 5.6e-07 28.8 22.5 0.00013 21.0 22.5 2.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor IBR PF01485.21 CDJ97608.1 - 0.00089 19.4 10.6 0.00089 19.4 10.6 3.0 3 0 0 3 3 3 1 IBR domain, a half RING-finger domain Peptidase_C13 PF01650.18 CDJ97610.1 - 1.9e-83 279.9 0.0 1.3e-68 231.3 0.2 2.2 1 1 1 2 2 2 2 Peptidase C13 family Peptidase_C14 PF00656.22 CDJ97610.1 - 0.00014 21.9 0.1 0.00028 20.9 0.1 1.5 1 1 0 1 1 1 1 Caspase domain DUF2675 PF11247.8 CDJ97610.1 - 0.082 13.1 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2675) NolV PF06635.12 CDJ97610.1 - 0.21 10.9 0.1 0.33 10.3 0.1 1.2 1 0 0 1 1 1 0 Nodulation protein NolV Cyclase_polyket PF04673.12 CDJ97611.1 - 0.019 15.2 0.6 0.025 14.8 0.6 1.1 1 0 0 1 1 1 0 Polyketide synthesis cyclase Cadherin PF00028.17 CDJ97612.1 - 5.8e-50 167.7 0.7 1.7e-08 34.8 0.0 7.0 5 2 1 6 6 6 6 Cadherin domain Cadherin_2 PF08266.12 CDJ97612.1 - 0.038 13.8 0.0 6.9 6.6 0.0 3.6 4 1 0 4 4 4 0 Cadherin-like DUF5512 PF17631.2 CDJ97612.1 - 0.14 12.1 0.7 20 5.2 0.0 3.4 2 1 1 3 3 3 0 Family of unknown function (DUF5512) V_ATPase_I PF01496.19 CDJ97613.1 - 0.099 10.5 0.7 0.11 10.4 0.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Vir_act_alpha_C PF10400.9 CDJ97613.1 - 0.12 13.0 2.7 1.2 9.9 0.2 2.3 2 0 0 2 2 2 0 Virulence activator alpha C-term Ribosomal_L29 PF00831.23 CDJ97613.1 - 0.18 11.8 6.1 2.9 7.9 1.8 2.4 2 0 0 2 2 2 0 Ribosomal L29 protein Atg14 PF10186.9 CDJ97613.1 - 0.29 10.2 4.1 0.4 9.7 4.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Nup54 PF13874.6 CDJ97613.1 - 0.69 10.0 6.0 0.65 10.1 4.3 1.7 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 FUSC PF04632.12 CDJ97613.1 - 2.8 6.4 3.8 3.5 6.0 3.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Pkinase PF00069.25 CDJ97614.1 - 1.4e-58 198.4 0.0 1.8e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ97614.1 - 7.5e-30 104.1 0.0 1.5e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ97614.1 - 0.003 16.9 0.2 0.0051 16.2 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ97614.1 - 0.01 15.8 0.1 0.1 12.5 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family CDP-OH_P_transf PF01066.21 CDJ97616.1 - 5.2e-17 62.4 0.1 5.2e-17 62.4 0.1 3.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Terminase_3 PF04466.13 CDJ97616.1 - 0.035 13.6 0.1 0.062 12.8 0.1 1.3 1 0 0 1 1 1 0 Phage terminase large subunit Redoxin PF08534.10 CDJ97616.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Redoxin Trypan_PARP PF05887.11 CDJ97617.1 - 0.0028 17.7 39.8 0.029 14.4 18.0 2.4 1 1 1 2 2 2 2 Procyclic acidic repetitive protein (PARP) Glycogen_syn PF05693.13 CDJ97618.1 - 2.1e-144 482.5 0.0 3e-144 482.0 0.0 1.1 1 0 0 1 1 1 1 Glycogen synthase 7tm_1 PF00001.21 CDJ97618.1 - 7.1e-26 91.1 13.7 1.3e-25 90.3 13.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Glycos_transf_1 PF00534.20 CDJ97618.1 - 0.00021 20.9 0.0 0.00039 20.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CDJ97618.1 - 0.002 18.5 0.0 0.0044 17.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 HTH_26 PF13443.6 CDJ97619.1 - 0.00025 21.4 0.1 0.00054 20.4 0.1 1.5 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_IclR PF09339.10 CDJ97619.1 - 0.0034 17.1 0.1 0.0062 16.3 0.1 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 CDJ97619.1 - 0.0095 15.8 0.1 0.022 14.6 0.1 1.6 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 CDJ97619.1 - 0.01 15.4 0.0 0.077 12.6 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_ISL3 PF13542.6 CDJ97619.1 - 0.029 13.8 0.1 0.078 12.4 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4_2 PF08281.12 CDJ97619.1 - 0.035 13.8 0.5 0.75 9.5 0.0 2.6 3 0 0 3 3 3 0 Sigma-70, region 4 CENP-B_N PF04218.13 CDJ97619.1 - 0.04 13.6 0.4 0.097 12.3 0.0 1.9 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain DUF3602 PF12223.8 CDJ97619.1 - 0.05 14.2 1.0 0.074 13.7 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) LacI PF00356.21 CDJ97619.1 - 0.052 13.4 0.3 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_3 PF01381.22 CDJ97619.1 - 0.073 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix HTH_32 PF13565.6 CDJ97619.1 - 0.32 11.6 4.7 0.31 11.7 0.3 2.5 3 0 0 3 3 3 0 Homeodomain-like domain RVT_1 PF00078.27 CDJ97620.1 - 8.6e-23 81.0 0.0 1.4e-22 80.3 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glycogen_syn PF05693.13 CDJ97621.1 - 2e-122 409.9 0.8 2.4e-122 409.7 0.8 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_4 PF13439.6 CDJ97621.1 - 2.2e-06 27.8 0.3 3.3e-06 27.2 0.3 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 CDJ97621.1 - 0.0002 21.1 0.3 0.0003 20.6 0.3 1.2 1 0 0 1 1 1 1 Starch synthase catalytic domain CX PF01705.19 CDJ97622.1 - 0.00024 21.6 11.6 0.0091 16.5 1.1 2.9 3 0 0 3 3 3 2 CX module NERD PF08378.11 CDJ97622.1 - 0.029 14.8 0.0 0.047 14.2 0.0 1.3 1 0 0 1 1 1 0 Nuclease-related domain 7TM_GPCR_Srv PF10323.9 CDJ97623.1 - 1.3e-20 73.9 15.9 1.5e-20 73.7 15.9 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Srg PF02118.21 CDJ97623.1 - 3.1e-10 40.2 16.1 4.4e-10 39.7 16.1 1.2 1 0 0 1 1 1 1 Srg family chemoreceptor 7TM_GPCR_Srx PF10328.9 CDJ97623.1 - 3.9e-09 36.5 6.4 3.9e-09 36.5 6.4 1.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 CDJ97623.1 - 6.6e-07 28.9 12.1 8.9e-07 28.5 11.1 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GCS PF03074.16 CDJ97625.1 - 1.1e-93 314.6 0.0 1.2e-93 314.4 0.0 1.0 1 0 0 1 1 1 1 Glutamate-cysteine ligase MAM PF00629.23 CDJ97626.1 - 5.4e-10 39.4 0.0 0.00012 22.0 0.0 2.3 2 0 0 2 2 2 2 MAM domain, meprin/A5/mu 7tm_1 PF00001.21 CDJ97627.1 - 5.6e-39 134.0 18.1 7.2e-39 133.7 18.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ToxS PF17323.2 CDJ97628.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Trans-membrane regulatory protein ToxS MFS_1 PF07690.16 CDJ97630.1 - 2.4e-06 26.7 2.2 0.0048 15.9 0.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Neur_chan_LBD PF02931.23 CDJ97631.1 - 5.4e-43 147.0 2.4 7.5e-43 146.5 2.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ97631.1 - 7.9e-21 75.2 10.2 7.1e-17 62.3 5.1 2.2 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region p450 PF00067.22 CDJ97632.1 - 1.3e-86 291.2 0.1 1.5e-86 291.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cullin PF00888.22 CDJ97632.1 - 0.03 12.9 0.1 0.05 12.2 0.1 1.3 1 1 0 1 1 1 0 Cullin family Transposase_1 PF01359.18 CDJ97633.1 - 8.3e-07 28.7 0.5 1.4e-06 28.0 0.5 1.4 1 0 0 1 1 1 1 Transposase (partial DDE domain) Abhydrolase_1 PF00561.20 CDJ97634.1 - 1.4e-27 97.0 0.1 6.8e-27 94.7 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ97634.1 - 6.3e-19 69.5 0.0 8.1e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDJ97634.1 - 4.9e-12 45.6 0.0 1.2e-10 41.1 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 CDJ97634.1 - 2.7e-06 26.3 0.0 7e-06 24.9 0.0 1.7 1 1 0 1 1 1 1 Ndr family DUF499 PF04465.12 CDJ97635.1 - 0.059 11.1 0.0 0.059 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF499) OAD_gamma PF04277.13 CDJ97635.1 - 0.14 12.8 1.8 0.21 12.2 1.8 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Ras PF00071.22 CDJ97637.1 - 1.5e-64 216.5 0.4 1.7e-64 216.3 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ97637.1 - 5.2e-36 123.5 0.3 7.5e-36 123.0 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ97637.1 - 4.9e-16 58.7 0.2 6.2e-16 58.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ97637.1 - 4e-07 29.6 0.2 5e-07 29.3 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CDJ97637.1 - 2.6e-05 23.7 0.1 3.4e-05 23.4 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CDJ97637.1 - 0.00057 20.0 0.1 0.001 19.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ97637.1 - 0.00058 19.5 0.2 0.0015 18.2 0.1 1.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 CDJ97637.1 - 0.032 13.6 0.0 0.076 12.4 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 CDJ97637.1 - 0.056 13.0 0.0 0.11 12.0 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 CDJ97637.1 - 0.073 12.3 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 CDJ97637.1 - 0.078 12.7 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CDJ97637.1 - 0.087 12.7 0.2 1.5 8.7 0.0 2.2 1 1 0 2 2 2 0 RsgA GTPase AAA_15 PF13175.6 CDJ97637.1 - 0.096 12.4 0.2 0.13 12.0 0.2 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 CDJ97637.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 CDJ97637.1 - 0.12 12.8 0.1 0.27 11.6 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3963 PF13124.6 CDJ97637.1 - 0.17 11.9 0.2 0.41 10.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) zf-H2C2_2 PF13465.6 CDJ97638.1 - 7.1e-20 70.5 17.7 1.3e-08 34.8 1.1 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 CDJ97638.1 - 2.2e-18 65.6 25.7 7e-06 26.2 3.5 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ97638.1 - 2.8e-12 46.4 22.8 0.0014 19.3 2.1 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDJ97638.1 - 4.6e-05 23.3 15.3 0.0015 18.5 1.2 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 CDJ97638.1 - 0.00013 22.2 11.4 0.11 12.8 1.9 3.2 2 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 CDJ97638.1 - 0.0014 18.9 3.1 0.13 12.5 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 CDJ97638.1 - 0.0014 19.3 2.5 0.0038 17.9 2.5 1.7 1 0 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats DUF2225 PF09986.9 CDJ97638.1 - 0.0054 16.5 2.2 0.28 10.9 2.3 2.6 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) zf_C2H2_ZHX PF18387.1 CDJ97638.1 - 0.0084 15.7 10.2 0.096 12.3 0.1 3.8 2 1 2 4 4 4 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_5 PF13909.6 CDJ97638.1 - 0.015 15.1 0.4 0.015 15.1 0.4 3.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain DZR PF12773.7 CDJ97638.1 - 0.047 13.7 3.8 1.2 9.2 0.5 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-met PF12874.7 CDJ97638.1 - 0.051 14.0 9.6 2.4 8.7 0.3 4.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 CDJ97638.1 - 0.14 12.2 9.7 0.05 13.7 1.4 3.2 2 1 0 2 2 2 0 Zinc ribbon domain C1_1 PF00130.22 CDJ97638.1 - 0.24 11.3 4.1 3.7 7.5 1.9 2.9 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.21 CDJ97638.1 - 0.38 10.9 8.4 0.37 11.0 4.6 2.4 2 0 0 2 2 2 0 FYVE zinc finger zinc_ribbon_15 PF17032.5 CDJ97638.1 - 1.7 9.5 6.0 9.2 7.1 0.4 2.4 1 1 1 2 2 2 0 zinc-ribbon family zf_UBZ PF18439.1 CDJ97638.1 - 3 7.5 9.0 7.1 6.3 0.0 3.5 4 0 0 4 4 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 CDJ97638.1 - 5.4 7.4 16.0 21 5.5 3.9 4.3 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 CDJ97638.1 - 9 6.2 7.2 9 6.2 1.6 3.1 1 1 0 2 2 2 0 GAGA factor OrsD PF12013.8 CDJ97638.1 - 9.6 6.7 11.7 24 5.4 0.3 3.7 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Epimerase PF01370.21 CDJ97641.1 - 8.7e-20 71.2 0.2 6.5e-15 55.2 0.0 4.0 3 1 0 3 3 3 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CDJ97641.1 - 9.5e-15 54.8 0.1 2.9e-14 53.2 0.0 1.8 2 1 1 3 3 3 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CDJ97641.1 - 7.1e-12 45.1 0.0 3e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 CDJ97641.1 - 7.5e-06 26.0 0.1 0.0006 19.8 0.0 2.3 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CDJ97641.1 - 8e-05 21.8 0.3 0.00019 20.6 0.2 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CDJ97641.1 - 0.00023 20.4 0.0 0.66 9.0 0.0 3.1 2 1 0 2 2 2 2 RmlD substrate binding domain KR PF08659.10 CDJ97641.1 - 0.0033 17.4 0.0 0.019 14.9 0.0 2.1 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.12 CDJ97641.1 - 0.031 13.4 0.9 0.89 8.7 0.3 2.8 2 1 0 2 2 2 0 Male sterility protein DapB_N PF01113.20 CDJ97641.1 - 0.059 13.5 1.0 4.7 7.3 0.0 2.9 3 1 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus Peptidase_M14 PF00246.24 CDJ97643.1 - 2.5e-94 316.3 0.0 3.2e-94 316.0 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 CDJ97643.1 - 7.2e-18 64.8 0.9 2.1e-17 63.3 0.4 2.1 2 0 0 2 2 2 1 Carboxypeptidase activation peptide ShK PF01549.24 CDJ97643.1 - 1.3e-06 28.8 9.4 2.3e-06 28.0 9.4 1.4 1 0 0 1 1 1 1 ShK domain-like Peptidase_M14 PF00246.24 CDJ97644.1 - 2.6e-88 296.6 0.0 3.2e-88 296.3 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 CDJ97644.1 - 3.3e-08 33.8 0.2 9.6e-08 32.3 0.2 1.7 1 0 0 1 1 1 1 Carboxypeptidase activation peptide ShK PF01549.24 CDJ97644.1 - 4.2e-07 30.4 4.7 1.1e-06 29.0 4.7 1.8 1 0 0 1 1 1 1 ShK domain-like Lebercilin PF15619.6 CDJ97645.1 - 0.0021 17.7 12.7 0.082 12.6 1.6 2.3 2 0 0 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease SKA1 PF07160.12 CDJ97645.1 - 0.0039 17.1 2.0 0.58 10.0 1.6 2.3 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 1 MutS_IV PF05190.18 CDJ97645.1 - 0.045 14.1 1.2 0.35 11.2 0.0 2.3 2 0 0 2 2 2 0 MutS family domain IV DUF3287 PF11690.8 CDJ97645.1 - 0.12 12.1 2.5 0.29 10.9 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) UPF0242 PF06785.11 CDJ97645.1 - 0.18 11.9 5.8 2.6 8.1 3.6 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus SOGA PF11365.8 CDJ97645.1 - 0.19 12.9 5.8 1.8 9.7 0.1 3.1 2 1 1 3 3 3 0 Protein SOGA FliD_N PF02465.18 CDJ97645.1 - 0.23 12.2 0.9 0.9 10.3 0.8 1.8 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus PI3K_P85_iSH2 PF16454.5 CDJ97645.1 - 0.25 10.9 11.7 2.9 7.4 0.2 3.0 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Cnn_1N PF07989.11 CDJ97645.1 - 0.27 11.4 12.2 2.3 8.4 0.2 3.2 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 CENP-F_leu_zip PF10473.9 CDJ97645.1 - 0.33 11.0 9.4 4.7 7.2 3.6 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LMBR1 PF04791.16 CDJ97645.1 - 0.34 9.7 3.1 0.45 9.4 3.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ATG16 PF08614.11 CDJ97645.1 - 0.44 10.7 9.8 2.4 8.3 0.9 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 CDJ97645.1 - 0.54 10.3 2.6 7.2 6.7 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) PspA_IM30 PF04012.12 CDJ97645.1 - 1.3 8.6 6.3 1.8 8.1 0.1 2.1 2 0 0 2 2 2 0 PspA/IM30 family KxDL PF10241.9 CDJ97645.1 - 1.3 9.3 7.2 4.6 7.6 0.2 2.7 2 1 1 3 3 3 0 Uncharacterized conserved protein DHR10 PF18595.1 CDJ97645.1 - 1.5 8.9 10.1 0.87 9.7 1.4 2.4 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Csm1_N PF18504.1 CDJ97645.1 - 1.9 8.9 6.6 2.4 8.6 1.6 2.6 2 1 0 2 2 2 0 Csm1 N-terminal domain Rootletin PF15035.6 CDJ97645.1 - 2.5 8.1 14.1 0.69 9.9 1.8 2.3 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion ZapB PF06005.12 CDJ97645.1 - 4.4 7.8 12.8 9.3 6.8 4.8 3.1 2 1 0 2 2 2 0 Cell division protein ZapB JIP_LZII PF16471.5 CDJ97645.1 - 9.3 6.5 9.3 2.1 8.6 0.7 2.6 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II Aminotran_1_2 PF00155.21 CDJ97646.1 - 0.02 14.1 0.5 0.028 13.6 0.5 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II TSC22 PF01166.18 CDJ97646.1 - 0.048 14.0 0.8 0.048 14.0 0.8 2.4 1 1 2 3 3 3 0 TSC-22/dip/bun family SEO_N PF14576.6 CDJ97646.1 - 0.061 12.5 3.4 0.069 12.3 2.5 1.4 1 1 0 1 1 1 0 Sieve element occlusion N-terminus Jnk-SapK_ap_N PF09744.9 CDJ97646.1 - 0.15 12.2 13.8 1.3 9.3 3.1 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Hpt PF01627.23 CDJ97646.1 - 0.33 11.2 7.5 2.4 8.5 7.5 2.2 1 1 0 1 1 1 0 Hpt domain Syntaxin-6_N PF09177.11 CDJ97646.1 - 0.34 11.5 4.9 0.67 10.6 4.0 1.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal GIT_CC PF16559.5 CDJ97646.1 - 0.57 10.1 14.2 0.12 12.3 8.5 2.7 2 1 2 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.21 CDJ97646.1 - 0.73 10.0 8.5 0.13 12.4 3.7 2.0 2 0 0 2 2 2 0 bZIP transcription factor YabA PF06156.13 CDJ97646.1 - 0.81 10.4 5.4 2.2 8.9 5.4 1.9 1 1 0 1 1 1 0 Initiation control protein YabA HR1 PF02185.16 CDJ97646.1 - 3.3 7.9 13.4 15 5.7 13.4 2.1 1 1 0 1 1 1 0 Hr1 repeat Sulfotransfer_2 PF03567.14 CDJ97648.1 - 9.9e-12 45.3 0.5 1.1e-11 45.1 0.5 1.0 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 CDJ97649.1 - 4.1e-28 99.0 9.4 4.8e-28 98.7 9.4 1.1 1 0 0 1 1 1 1 Sulfotransferase family Herpes_TK PF00693.18 CDJ97649.1 - 0.049 12.9 0.1 0.092 12.0 0.1 1.4 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus Adipogenin PF15202.6 CDJ97650.1 - 0.0041 17.1 0.7 0.0041 17.1 0.7 3.2 2 1 1 3 3 3 1 Adipogenin TerB_C PF15615.6 CDJ97650.1 - 0.082 13.2 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 TerB-C domain Atthog PF18800.1 CDJ97650.1 - 0.37 10.7 6.5 0.075 12.9 1.6 2.1 2 0 0 2 2 2 0 Attenuator of Hedgehog DUF996 PF06195.13 CDJ97650.1 - 2.4 8.5 7.7 0.31 11.3 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF996) SUR7 PF06687.12 CDJ97650.1 - 4 7.0 9.2 0.056 13.1 1.1 1.9 2 1 0 2 2 2 0 SUR7/PalI family LapA_dom PF06305.11 CDJ97650.1 - 8.8 6.2 9.8 2.6 7.9 0.3 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain zf-H2C2_2 PF13465.6 CDJ97651.1 - 1.5e-05 25.2 32.9 0.0044 17.4 0.1 7.8 8 0 0 8 8 8 3 Zinc-finger double domain DUF2719 PF10891.8 CDJ97651.1 - 0.00018 21.3 11.5 0.46 10.4 2.5 3.9 4 0 0 4 4 4 3 Protein of unknown function (DUF2719) zf-H2C2_5 PF13909.6 CDJ97651.1 - 0.0036 17.0 1.0 0.0036 17.0 1.0 7.7 8 0 0 8 8 8 3 C2H2-type zinc-finger domain Exonuc_VII_L PF02601.15 CDJ97651.1 - 0.049 13.2 1.1 0.074 12.6 1.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-C2H2_4 PF13894.6 CDJ97651.1 - 0.05 14.5 59.9 1.8 9.6 1.0 8.5 8 0 0 8 8 8 0 C2H2-type zinc finger PAS_2 PF08446.11 CDJ97651.1 - 0.092 13.4 0.3 6.8 7.4 0.0 2.8 3 0 0 3 3 3 0 PAS fold Elf1 PF05129.13 CDJ97651.1 - 7.5 6.7 28.4 0.5 10.4 5.5 5.1 5 0 0 5 5 5 0 Transcription elongation factor Elf1 like Mlf1IP PF10248.9 CDJ97652.1 - 1.2e-35 123.0 1.9 1.9e-35 122.4 1.9 1.3 1 0 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein Aminotran_1_2 PF00155.21 CDJ97653.1 - 2.4e-26 92.8 0.0 4e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4477 PF14780.6 CDJ97653.1 - 6.1e-09 35.8 0.0 1.2e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) Cys_Met_Meta_PP PF01053.20 CDJ97653.1 - 0.0052 15.4 0.1 0.02 13.4 0.0 1.9 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme SR-25 PF10500.9 CDJ97653.1 - 0.24 11.0 31.7 0.61 9.7 16.3 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Trehalase PF01204.18 CDJ97654.1 - 2e-148 495.4 1.4 2.3e-148 495.2 1.4 1.0 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 CDJ97654.1 - 9.7e-06 24.7 1.5 6.8e-05 22.0 1.5 2.1 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Gal-bind_lectin PF00337.22 CDJ97654.1 - 0.087 12.4 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 Galactoside-binding lectin PseudoU_synth_1 PF01416.20 CDJ97654.1 - 0.16 12.4 0.0 0.37 11.3 0.0 1.6 1 0 0 1 1 1 0 tRNA pseudouridine synthase AKAP7_NLS PF10469.9 CDJ97655.1 - 1.9e-38 132.5 0.0 3.8e-38 131.4 0.0 1.5 2 0 0 2 2 2 1 AKAP7 2'5' RNA ligase-like domain Aminotran_1_2 PF00155.21 CDJ97655.1 - 3.5e-12 46.2 0.0 4.9e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II KH_1 PF00013.29 CDJ97655.1 - 1.4e-08 34.4 0.0 3.7e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 KH domain Sugar_tr PF00083.24 CDJ97656.1 - 1.2e-59 202.3 24.9 1.4e-59 202.2 24.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ97656.1 - 1e-19 70.7 23.5 7.6e-13 48.1 9.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF485 PF04341.12 CDJ97656.1 - 8.2 6.5 17.9 0.39 10.7 1.0 3.8 3 1 1 4 4 4 0 Protein of unknown function, DUF485 ATP-synt_ab PF00006.25 CDJ97657.1 - 4.7e-109 363.0 0.0 6.6e-109 362.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 CDJ97657.1 - 1.6e-40 137.7 0.0 2.8e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 CDJ97657.1 - 1.1e-12 48.2 1.9 2.4e-12 47.2 1.9 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain His_Phos_2 PF00328.22 CDJ97657.1 - 5.1e-12 45.8 0.0 1.1e-07 31.6 0.0 3.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF2207 PF09972.9 CDJ97658.1 - 0.046 12.5 0.0 0.046 12.5 0.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Phage_holin_6_1 PF09682.10 CDJ97658.1 - 0.053 13.9 3.4 1.3 9.5 0.1 2.4 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) SID-1_RNA_chan PF13965.6 CDJ97658.1 - 0.054 11.9 0.6 0.073 11.5 0.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MscL PF01741.18 CDJ97658.1 - 0.055 13.8 0.3 0.055 13.8 0.3 2.4 2 1 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL Phage_holin_3_6 PF07332.11 CDJ97658.1 - 0.056 13.5 0.5 0.11 12.6 0.5 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III SARAF PF06682.12 CDJ97658.1 - 0.057 13.1 4.4 0.27 10.8 3.6 2.0 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis YajC PF02699.15 CDJ97658.1 - 0.068 13.1 0.8 0.068 13.1 0.8 3.5 2 2 1 3 3 3 0 Preprotein translocase subunit HemY_N PF07219.13 CDJ97658.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 HemY protein N-terminus RE_TdeIII PF09520.10 CDJ97658.1 - 0.82 9.3 6.5 1.4 8.5 6.5 1.3 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII EphA2_TM PF14575.6 CDJ97658.1 - 1.3 9.9 0.0 1.3 9.9 0.0 2.4 2 1 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 CDJ97658.1 - 3.1 8.2 7.0 1.2 9.5 0.1 2.5 2 1 0 2 2 2 0 Orf78 (ac78) LapA_dom PF06305.11 CDJ97658.1 - 4.1 7.3 6.5 0.32 10.8 0.5 2.3 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Hyd_WA PF06462.12 CDJ97659.1 - 2.7e-25 88.0 32.3 3.6e-12 46.0 0.6 8.4 8 0 0 8 8 8 6 Propeller Pex24p PF06398.11 CDJ97659.1 - 7.1e-11 41.7 14.0 5.3e-06 25.7 0.9 2.2 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin GRAM PF02893.20 CDJ97659.1 - 0.069 13.0 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 GRAM domain ATP-synt_C PF00137.21 CDJ97660.1 - 9.1e-24 83.6 31.5 1.5e-13 50.8 8.7 2.9 3 0 0 3 3 3 2 ATP synthase subunit C Phage_holin_2_3 PF16080.5 CDJ97660.1 - 0.2 11.5 2.6 0.49 10.2 0.0 3.0 3 0 0 3 3 3 0 Bacteriophage holin family HP1 MAGI_u1 PF16663.5 CDJ97662.1 - 0.0095 16.0 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Unstructured region on MAGI DUF4345 PF14248.6 CDJ97662.1 - 0.53 10.2 7.9 0.054 13.4 2.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4345) Wzy_C PF04932.15 CDJ97662.1 - 7.4 6.2 8.2 18 5.0 8.2 1.6 1 1 0 1 1 1 0 O-Antigen ligase zf_ZIC PF18366.1 CDJ97663.1 - 0.035 14.2 0.4 0.07 13.2 0.4 1.5 1 0 0 1 1 1 0 Zic proteins zinc finger domain zf-C2H2 PF00096.26 CDJ97663.1 - 0.058 13.9 0.1 0.18 12.3 0.1 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ97663.1 - 0.15 13.0 0.3 0.76 10.8 0.0 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDJ97663.1 - 0.7 10.0 0.0 0.7 10.0 0.0 2.2 3 0 0 3 3 3 0 C2H2-type zinc finger MCM PF00493.23 CDJ97664.1 - 2.4e-90 301.5 0.1 3.3e-90 301.1 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 CDJ97664.1 - 2.1e-26 92.1 1.0 5.6e-26 90.8 1.0 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 CDJ97664.1 - 5.4e-09 35.7 0.0 9.5e-08 31.7 0.0 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI MCM6_C PF18263.1 CDJ97664.1 - 7e-09 35.9 0.8 1.5e-08 34.8 0.1 1.9 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain AAA_5 PF07728.14 CDJ97664.1 - 3.5e-05 23.8 0.0 0.00012 22.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CDJ97664.1 - 4.1e-05 23.5 0.0 8.1e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CDJ97664.1 - 0.0036 17.0 0.1 0.0094 15.7 0.0 1.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_lid_7 PF17867.1 CDJ97664.1 - 0.004 17.3 0.1 0.0095 16.1 0.1 1.6 1 0 0 1 1 1 1 Midasin AAA lid domain Mg_chelatase_C PF13335.6 CDJ97664.1 - 0.22 12.1 3.5 0.76 10.5 1.9 2.6 1 1 2 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal Moulting_cycle PF04870.16 CDJ97665.1 - 3.9e-09 36.2 0.7 7.8e-08 32.0 0.7 2.0 1 1 0 1 1 1 1 Moulting cycle 7TM_GPCR_Srab PF10292.9 CDJ97666.1 - 8.6e-58 195.8 15.9 9.8e-58 195.6 15.9 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Srb PF02175.16 CDJ97666.1 - 3e-07 30.5 19.1 3.9e-07 30.1 18.3 1.5 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srb 7TM_GPCR_Sra PF02117.16 CDJ97666.1 - 9.8e-07 27.9 14.6 1.2e-06 27.7 14.6 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sra Sre PF03125.18 CDJ97666.1 - 2.2e-05 23.8 27.5 0.0003 20.1 27.5 2.8 1 1 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor Terminase_3 PF04466.13 CDJ97668.1 - 9.5e-22 77.5 0.0 1.6e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Phage terminase large subunit Terminase_2 PF03592.16 CDJ97668.1 - 5.1e-13 49.7 6.3 1.6e-12 48.1 5.0 2.3 1 1 1 2 2 2 1 Terminase small subunit Vip3A_N PF12495.8 CDJ97669.1 - 1.3e-05 25.1 0.6 0.19 11.6 0.1 2.5 2 0 0 2 2 2 2 Vegetative insecticide protein 3A N terminal CdvA PF18822.1 CDJ97669.1 - 0.00038 20.3 7.9 0.092 12.6 0.2 4.0 4 0 0 4 4 4 2 CdvA-like coiled-coil domain SNAD3 PF18749.1 CDJ97669.1 - 0.00098 18.4 2.3 0.35 10.0 0.2 2.3 2 0 0 2 2 2 2 Secreted Novel AID/APOBEC-like Deaminase 3 DUF948 PF06103.11 CDJ97669.1 - 0.0015 18.7 11.2 0.17 12.2 0.0 4.4 4 1 0 4 4 3 2 Bacterial protein of unknown function (DUF948) DUF3341 PF11821.8 CDJ97669.1 - 0.004 16.8 9.0 0.035 13.7 0.0 4.0 3 1 1 4 4 4 1 Protein of unknown function (DUF3341) ALIX_LYPXL_bnd PF13949.6 CDJ97669.1 - 0.0044 16.4 6.1 0.43 9.8 0.0 4.0 4 0 0 4 4 4 1 ALIX V-shaped domain binding to HIV DUF2203 PF09969.9 CDJ97669.1 - 0.0047 17.6 0.6 9.2 7.0 0.0 3.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Ribosomal_S6 PF01250.17 CDJ97669.1 - 0.0066 16.7 2.0 3.5 8.0 0.0 3.2 3 0 0 3 3 3 1 Ribosomal protein S6 PTPA PF03095.15 CDJ97669.1 - 0.0077 15.7 1.0 0.12 11.8 0.0 3.1 4 0 0 4 4 4 1 Phosphotyrosyl phosphate activator (PTPA) protein Sulfatase_C PF14707.6 CDJ97669.1 - 0.0092 16.7 3.1 14 6.4 0.1 3.8 3 0 0 3 3 3 0 C-terminal region of aryl-sulfatase NPV_P10 PF05531.12 CDJ97669.1 - 0.036 14.5 4.8 7.4 7.1 0.1 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein tRNA-synt_2b PF00587.25 CDJ97669.1 - 0.043 13.8 3.1 1.3 9.0 0.1 3.3 3 1 0 3 3 3 0 tRNA synthetase class II core domain (G, H, P, S and T) DNA_repr_REX1B PF14966.6 CDJ97669.1 - 0.053 14.2 8.2 2.7 8.7 0.1 3.9 4 1 1 5 5 3 0 DNA repair REX1-B DUF4423 PF14394.6 CDJ97669.1 - 0.063 13.0 5.8 3 7.5 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) T4SS PF07996.11 CDJ97669.1 - 0.076 13.4 0.3 10 6.5 0.0 2.9 3 0 0 3 3 2 0 Type IV secretion system proteins Casc1_N PF15927.5 CDJ97669.1 - 0.086 12.5 2.0 13 5.4 0.1 2.9 3 0 0 3 3 3 0 Cancer susceptibility candidate 1 N-terminus FANCI_S4 PF14678.6 CDJ97669.1 - 0.09 11.9 0.0 0.09 11.9 0.0 2.0 3 0 0 3 3 2 0 FANCI solenoid 4 DUF4298 PF14131.6 CDJ97669.1 - 0.094 12.7 5.5 6.9 6.7 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) MCPsignal PF00015.21 CDJ97669.1 - 0.1 12.4 1.4 52 3.6 0.0 3.8 4 0 0 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CHDCT2 PF08074.11 CDJ97669.1 - 0.11 12.7 1.9 4.3 7.5 0.1 2.8 3 0 0 3 3 2 0 CHDCT2 (NUC038) domain GrpE PF01025.19 CDJ97669.1 - 0.22 11.2 9.2 11 5.6 0.1 4.0 3 1 1 4 4 4 0 GrpE Mce4_CUP1 PF11887.8 CDJ97669.1 - 0.25 10.7 0.3 18 4.7 0.0 2.7 3 0 0 3 3 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Seryl_tRNA_N PF02403.22 CDJ97669.1 - 0.33 11.2 6.2 4.3 7.6 0.1 3.6 4 0 0 4 4 3 0 Seryl-tRNA synthetase N-terminal domain Lipoprotein_7 PF01540.16 CDJ97669.1 - 0.36 10.1 4.4 1.3 8.2 0.1 2.9 3 0 0 3 3 3 0 Adhesin lipoprotein DASH_Spc34 PF08657.10 CDJ97669.1 - 0.37 10.6 5.2 13 5.4 0.1 3.0 3 0 0 3 3 3 0 DASH complex subunit Spc34 Sec20 PF03908.13 CDJ97669.1 - 0.48 10.4 9.7 1.7 8.6 0.1 4.2 4 0 0 4 4 4 0 Sec20 Prominin PF05478.11 CDJ97669.1 - 0.55 8.1 17.7 0.12 10.4 0.1 3.9 3 1 1 4 4 3 0 Prominin YjcB PF15940.5 CDJ97669.1 - 0.58 10.4 7.0 6.1 7.1 0.1 3.1 3 0 0 3 3 2 0 Family of unknown function EzrA PF06160.12 CDJ97669.1 - 0.59 8.2 11.3 0.17 10.1 0.1 3.4 4 0 0 4 4 4 0 Septation ring formation regulator, EzrA Focal_AT PF03623.13 CDJ97669.1 - 0.75 9.8 2.8 18 5.3 0.1 3.0 3 0 0 3 3 3 0 Focal adhesion targeting region DUF2461 PF09365.10 CDJ97669.1 - 1.1 9.2 5.5 34 4.3 0.1 3.7 4 0 0 4 4 3 0 Conserved hypothetical protein (DUF2461) RSS_P20 PF11757.8 CDJ97669.1 - 1.2 9.6 5.6 19 5.7 0.1 3.1 2 1 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain Yip1 PF04893.17 CDJ97669.1 - 1.3 8.7 20.2 0.85 9.3 3.0 3.8 3 1 1 4 4 4 0 Yip1 domain FliJ PF02050.16 CDJ97669.1 - 1.8 8.8 8.6 17 5.6 0.0 3.7 4 0 0 4 4 3 0 Flagellar FliJ protein DUF2312 PF10073.9 CDJ97669.1 - 1.8 8.3 9.7 6.4 6.5 0.4 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) DASH_Duo1 PF08651.10 CDJ97669.1 - 3 7.7 7.3 21 5.0 0.3 3.6 3 0 0 3 3 3 0 DASH complex subunit Duo1 PhaP_Bmeg PF09602.10 CDJ97669.1 - 3.2 7.7 6.9 41 4.1 0.1 3.7 4 0 0 4 4 4 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) LAGLIDADG_WhiA PF14527.6 CDJ97669.1 - 3.4 7.8 7.3 4 7.6 0.3 3.1 4 0 0 4 4 2 0 WhiA LAGLIDADG-like domain DUF2207 PF09972.9 CDJ97669.1 - 7.9 5.1 19.3 0.17 10.6 1.8 3.8 3 1 0 4 4 4 0 Predicted membrane protein (DUF2207) A_deaminase PF00962.22 CDJ97670.1 - 2.9e-18 66.3 1.0 7.4e-11 41.9 0.2 2.1 1 1 0 2 2 2 2 Adenosine/AMP deaminase Sulfate_transp PF00916.20 CDJ97670.1 - 0.015 14.1 0.1 0.019 13.7 0.1 1.1 1 0 0 1 1 1 0 Sulfate permease family Cyd_oper_YbgE PF09600.10 CDJ97672.1 - 0.0093 16.3 2.5 0.0093 16.3 2.5 2.1 2 1 0 2 2 2 1 Cyd operon protein YbgE (Cyd_oper_YbgE) DUF4501 PF14946.6 CDJ97672.1 - 1.9 8.6 5.2 0.29 11.2 1.4 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4501) DUF3290 PF11694.8 CDJ97672.1 - 2.1 8.3 9.0 4.6 7.2 4.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Comm PF15957.5 CDJ97672.1 - 2.2 8.6 8.2 2.7 8.4 7.7 1.7 1 1 0 1 1 1 0 Commissureless Glycophorin_A PF01102.18 CDJ97673.1 - 0.14 12.4 0.1 0.14 12.4 0.1 2.8 3 0 0 3 3 3 0 Glycophorin A EGF PF00008.27 CDJ97674.1 - 0.013 15.7 3.5 0.023 15.0 3.5 1.3 1 0 0 1 1 1 0 EGF-like domain Pkinase_Tyr PF07714.17 CDJ97675.1 - 1.5e-12 47.4 0.0 2e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ97675.1 - 6.9e-05 22.3 0.1 9.8e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ97676.1 - 0.00017 21.0 0.0 0.00019 20.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Fringe PF02434.16 CDJ97677.1 - 6.5e-05 22.5 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Fringe-like Avl9 PF09794.9 CDJ97677.1 - 0.046 12.4 0.0 0.053 12.2 0.0 1.2 1 0 0 1 1 1 0 Transport protein Avl9 CHCH PF06747.13 CDJ97678.1 - 7.1e-08 32.4 6.4 1.1e-07 31.8 6.4 1.3 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.9 CDJ97678.1 - 3.6e-06 27.2 9.0 4.7e-06 26.8 9.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Cmc1 PF08583.10 CDJ97678.1 - 0.011 15.8 1.2 0.015 15.3 1.2 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like NAD_binding_2 PF03446.15 CDJ97679.1 - 8.9e-43 146.2 0.7 1.2e-42 145.7 0.7 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CDJ97679.1 - 2.2e-32 111.9 0.0 3.9e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 CDJ97679.1 - 1.5e-06 27.7 0.0 2.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CDJ97679.1 - 1.4e-05 25.5 0.1 8.2e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 CDJ97679.1 - 0.00024 21.0 0.3 0.0052 16.7 0.3 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 CDJ97679.1 - 0.016 15.4 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 CDJ97679.1 - 0.031 13.9 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyoxalase PF00903.25 CDJ97680.1 - 1.1e-05 25.6 0.0 0.00012 22.2 0.0 2.4 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.6 CDJ97680.1 - 0.07 13.2 0.0 0.58 10.2 0.0 2.1 2 0 0 2 2 2 0 CppA N-terminal Acetyltransf_CG PF14542.6 CDJ97681.1 - 3e-21 75.3 0.0 3.8e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 CDJ97681.1 - 0.0083 16.4 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 CDJ97682.1 - 1.7e-18 66.5 0.0 2.1e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF4304 PF14137.6 CDJ97682.1 - 0.0016 18.6 0.0 0.34 11.1 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4304) Acetyltransf_1 PF00583.25 CDJ97682.1 - 0.0099 16.1 0.1 0.018 15.3 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDJ97682.1 - 0.066 13.7 0.1 0.14 12.6 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain JIP_LZII PF16471.5 CDJ97683.1 - 1.6e-28 98.7 15.1 2.1e-28 98.3 7.9 2.5 2 0 0 2 2 2 2 JNK-interacting protein leucine zipper II RILP PF11461.8 CDJ97683.1 - 0.067 13.4 0.3 0.067 13.4 0.3 2.9 2 0 0 2 2 2 0 Rab interacting lysosomal protein SlyX PF04102.12 CDJ97683.1 - 1.9 9.2 8.2 1.1 9.9 3.1 2.8 2 0 0 2 2 2 0 SlyX zf-CCCH PF00642.24 CDJ97684.1 - 3.4e-09 36.4 1.7 3.4e-09 36.4 1.7 1.8 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 CDJ97684.1 - 2.2e-07 30.6 5.5 4.3e-07 29.7 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ97684.1 - 1.1e-06 28.5 8.9 2.3e-06 27.5 8.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CDJ97684.1 - 1.9e-06 27.6 7.9 1.9e-06 27.6 7.9 2.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 CDJ97684.1 - 2.3e-06 27.5 3.3 2.3e-06 27.5 3.3 1.9 2 0 0 2 2 1 1 Zinc finger domain zf-C3HC4 PF00097.25 CDJ97684.1 - 9.1e-06 25.5 9.0 2.4e-05 24.1 9.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_4 PF18044.1 CDJ97684.1 - 1.3e-05 24.8 1.9 1.3e-05 24.8 1.9 2.4 2 0 0 2 2 2 1 CCCH-type zinc finger zf-RING_2 PF13639.6 CDJ97684.1 - 3e-05 24.3 6.9 3e-05 24.3 6.9 2.2 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 CDJ97684.1 - 0.0022 18.0 7.1 0.0066 16.5 7.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.5 CDJ97684.1 - 0.0063 16.6 4.1 0.0063 16.6 4.1 2.1 2 0 0 2 2 2 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 CDJ97684.1 - 0.014 15.2 5.6 0.031 14.1 5.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 CDJ97684.1 - 0.037 13.8 3.2 0.081 12.8 3.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-CCCH_2 PF14608.6 CDJ97684.1 - 0.047 14.2 2.3 0.13 12.8 2.3 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-C3HC4_4 PF15227.6 CDJ97684.1 - 0.17 12.0 7.8 0.48 10.6 7.8 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CDJ97684.1 - 0.25 11.7 6.3 0.074 13.4 2.5 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-P11 PF03854.14 CDJ97684.1 - 4.6 7.0 6.8 14 5.4 6.8 1.8 1 1 0 1 1 1 0 P-11 zinc finger zf-CCCH_8 PF18633.1 CDJ97684.1 - 8.3 6.6 8.3 0.69 10.1 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger antiviral protein (ZAP) zinc finger domain 3 ABC1 PF03109.16 CDJ97685.1 - 3.9e-34 117.4 0.0 6.7e-34 116.6 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Tetraspanin PF00335.20 CDJ97686.1 - 9.4e-17 61.5 12.4 1.2e-16 61.1 12.4 1.1 1 0 0 1 1 1 1 Tetraspanin family Cmc1 PF08583.10 CDJ97686.1 - 7.5e-07 29.1 0.3 1.5e-06 28.1 0.3 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF2250 PF10007.9 CDJ97686.1 - 0.078 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) YfhO PF09586.10 CDJ97686.1 - 0.27 9.4 2.6 0.36 9.0 2.6 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF3810 PF12725.7 CDJ97686.1 - 0.39 10.0 1.7 0.5 9.7 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) L6_membrane PF05805.12 CDJ97686.1 - 0.39 10.3 8.9 0.099 12.2 5.6 1.6 2 0 0 2 2 2 0 L6 membrane protein Nsp1_C PF05064.13 CDJ97687.1 - 0.03 14.1 0.1 0.044 13.6 0.1 1.2 1 0 0 1 1 1 0 Nsp1-like C-terminal region TMEM247 PF15444.6 CDJ97688.1 - 0.16 12.0 0.8 0.41 10.7 0.8 1.7 1 0 0 1 1 1 0 Transmembrane protein 247 KLRAQ PF10205.9 CDJ97688.1 - 0.73 10.1 0.0 0.73 10.1 0.0 3.1 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein V-SNARE_C PF12352.8 CDJ97689.1 - 4.2e-14 52.6 0.5 1.3e-13 51.0 0.5 1.9 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus ING PF12998.7 CDJ97689.1 - 0.0028 18.2 1.2 0.049 14.2 0.1 2.6 2 2 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding DUF1664 PF07889.12 CDJ97689.1 - 0.026 14.6 4.7 0.25 11.4 0.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 CDJ97689.1 - 0.031 14.5 3.4 0.45 10.8 0.2 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HAUS-augmin3 PF14932.6 CDJ97689.1 - 0.14 11.7 3.0 0.24 11.0 0.4 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Spc7 PF08317.11 CDJ97689.1 - 0.23 10.3 5.5 0.078 11.9 0.4 2.2 1 1 2 3 3 3 0 Spc7 kinetochore protein DpnI_C PF17726.1 CDJ97689.1 - 0.52 10.5 2.8 1.8 8.7 0.1 2.6 2 1 1 3 3 3 0 Dam-replacing HTH domain DUF16 PF01519.16 CDJ97689.1 - 0.69 10.4 3.7 15 6.1 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF4407 PF14362.6 CDJ97689.1 - 5.3 6.3 7.4 0.19 11.0 1.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Ribul_P_3_epim PF00834.19 CDJ97690.1 - 2.6e-64 216.3 0.0 3.3e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family DUF4434 PF14488.6 CDJ97690.1 - 0.0061 16.6 0.0 0.009 16.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4434) QRPTase_C PF01729.19 CDJ97690.1 - 0.06 13.1 0.1 0.37 10.6 0.1 2.1 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain PcrB PF01884.17 CDJ97690.1 - 0.079 12.4 0.8 0.33 10.4 0.8 2.1 1 1 0 1 1 1 0 PcrB family DUF2388 PF09498.10 CDJ97690.1 - 0.099 12.6 0.3 0.29 11.1 0.2 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2388) zf-RING_2 PF13639.6 CDJ97691.1 - 1.2e-12 47.9 4.9 2.2e-12 47.1 4.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ97691.1 - 3.6e-10 39.5 3.6 6.4e-10 38.7 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDJ97691.1 - 1.2e-09 37.7 2.0 2.5e-09 36.7 2.0 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 CDJ97691.1 - 1.1e-08 35.2 2.8 2.4e-08 34.1 2.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDJ97691.1 - 4.5e-08 32.8 2.6 7.5e-08 32.1 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ97691.1 - 1.9e-05 24.5 2.6 3.8e-05 23.6 2.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDJ97691.1 - 0.00043 20.2 2.7 0.00096 19.1 2.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CDJ97691.1 - 0.0017 18.2 3.0 0.0033 17.3 3.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CDJ97691.1 - 0.0027 17.5 1.8 0.0047 16.7 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ZNRF_3_ecto PF18212.1 CDJ97691.1 - 0.029 14.3 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 ZNRF-3 Ectodomain zf-ANAPC11 PF12861.7 CDJ97691.1 - 0.061 13.4 2.4 0.25 11.4 2.4 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 CDJ97691.1 - 0.13 12.2 2.5 0.24 11.3 2.5 1.5 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.6 CDJ97691.1 - 0.19 11.9 1.0 0.31 11.2 0.4 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.8 CDJ97691.1 - 0.28 11.4 2.9 0.89 9.8 2.9 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 CDJ97691.1 - 0.44 10.2 2.0 0.82 9.3 2.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-H2C2_2 PF13465.6 CDJ97692.1 - 0.012 16.1 63.3 0.07 13.6 0.9 10.5 12 0 0 12 12 12 0 Zinc-finger double domain PHZA_PHZB PF03284.13 CDJ97692.1 - 0.5 10.0 8.2 2.5 7.7 0.3 3.9 4 0 0 4 4 4 0 Phenazine biosynthesis protein A/B zf-Di19 PF05605.12 CDJ97692.1 - 1.6 9.1 76.5 0.034 14.4 9.7 8.5 7 2 2 9 9 9 0 Drought induced 19 protein (Di19), zinc-binding Glyco_trans_1_4 PF13692.6 CDJ97693.1 - 9.4e-07 29.3 0.0 1.6e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CDJ97693.1 - 5.4e-06 26.9 0.0 1.6e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 CDJ97693.1 - 3.2e-05 24.0 1.5 0.00029 20.9 1.5 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 CDJ97693.1 - 0.0014 18.2 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CDJ97693.1 - 0.13 12.7 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 JmjC PF02373.22 CDJ97695.1 - 8.1e-07 29.5 0.6 5.1e-05 23.7 0.6 2.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CDJ97695.1 - 3.5e-05 23.7 0.1 3.5e-05 23.7 0.1 2.9 2 1 0 2 2 2 1 Cupin-like domain JHD PF17811.1 CDJ97695.1 - 0.00013 22.5 0.3 0.00058 20.4 0.1 2.3 3 0 0 3 3 3 1 Jumonji helical domain Ilar_coat PF01787.16 CDJ97695.1 - 0.11 12.2 2.3 0.13 12.0 0.6 2.0 2 0 0 2 2 2 0 Ilarvirus coat protein Chromo_shadow PF01393.19 CDJ97696.1 - 1.1e-21 76.6 0.1 8.4e-20 70.6 0.0 2.2 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.24 CDJ97696.1 - 1.3e-19 69.8 3.6 4.4e-17 61.7 0.6 2.5 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 CDJ97696.1 - 8.3e-05 22.7 0.0 0.0032 17.6 0.0 2.2 2 0 0 2 2 2 1 Polycomb-like MTF2 factor 2 MerR_1 PF13411.6 CDJ97696.1 - 0.031 14.3 0.1 2 8.5 0.1 2.5 2 1 0 2 2 2 0 MerR HTH family regulatory protein DUF1918 PF08940.11 CDJ97696.1 - 0.092 12.4 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) 7TM_GPCR_Srsx PF10320.9 CDJ97698.1 - 0.00055 19.4 0.7 0.00069 19.1 0.2 1.4 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx HTH_Tnp_Tc3_2 PF01498.18 CDJ97699.1 - 9.7e-09 35.4 0.1 1.4e-08 34.9 0.1 1.3 1 0 0 1 1 1 1 Transposase HTH_Tnp_IS1 PF12759.7 CDJ97699.1 - 0.11 12.1 0.1 0.2 11.3 0.1 1.5 1 1 0 1 1 1 0 InsA C-terminal domain Pkinase PF00069.25 CDJ97700.1 - 1.2e-22 80.6 0.1 3.7e-22 79.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ97700.1 - 3.9e-15 55.8 0.0 6.7e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ97700.1 - 0.0062 15.4 0.3 0.96 8.1 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase SAM_decarbox PF01536.16 CDJ97700.1 - 0.0087 15.1 0.4 0.013 14.5 0.4 1.3 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase VWA PF00092.28 CDJ97701.1 - 0.0003 21.1 0.0 0.0003 21.1 0.0 3.2 3 1 1 4 4 4 1 von Willebrand factor type A domain Macoilin PF09726.9 CDJ97701.1 - 9.3 4.7 8.6 12 4.3 8.6 1.1 1 0 0 1 1 1 0 Macoilin family Ubie_methyltran PF01209.18 CDJ97704.1 - 4.6e-87 291.2 0.1 6.6e-87 290.7 0.1 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CDJ97704.1 - 1.2e-20 74.1 0.0 2.8e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ97704.1 - 1.5e-20 73.7 0.1 5.8e-20 71.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain DUF525 PF04379.14 CDJ97704.1 - 1.1e-17 64.0 0.1 2.4e-17 62.9 0.1 1.6 1 0 0 1 1 1 1 ApaG domain Methyltransf_31 PF13847.6 CDJ97704.1 - 2.7e-12 46.7 0.0 5.8e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ97704.1 - 1.5e-11 44.9 0.0 5.1e-11 43.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ97704.1 - 7.6e-09 35.6 0.0 4e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain YccV-like PF08755.11 CDJ97704.1 - 2.1e-05 24.9 0.0 4.9e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like MTS PF05175.14 CDJ97704.1 - 4.1e-05 23.2 0.1 0.00036 20.1 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 CDJ97704.1 - 0.0048 16.8 0.3 0.04 13.8 0.1 2.5 2 1 0 2 2 2 1 Hypothetical methyltransferase Spermine_synth PF01564.17 CDJ97704.1 - 0.021 14.2 0.1 0.049 13.0 0.1 1.5 1 0 0 1 1 1 0 Spermine/spermidine synthase domain Methyltransf_32 PF13679.6 CDJ97704.1 - 0.047 13.7 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 CDJ97704.1 - 0.083 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain ADH_zinc_N PF00107.26 CDJ97704.1 - 0.18 11.8 0.0 0.59 10.1 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase E2F_TDP PF02319.20 CDJ97706.1 - 2.2e-32 110.9 0.5 3.4e-18 65.4 0.4 2.7 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 CDJ97706.1 - 0.054 13.4 0.4 0.23 11.3 0.1 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Sushi PF00084.20 CDJ97707.1 - 1e-14 54.8 11.0 0.00012 22.5 0.2 4.3 4 0 0 4 4 4 4 Sushi repeat (SCR repeat) CBM_14 PF01607.24 CDJ97707.1 - 1.1 9.4 9.0 8.3 6.7 0.1 4.5 5 0 0 5 5 5 0 Chitin binding Peritrophin-A domain Pyr_redox_2 PF07992.14 CDJ97708.1 - 3.4e-33 115.1 0.0 1.2e-16 60.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CDJ97708.1 - 1.5e-07 30.9 0.0 4.3e-06 26.1 0.0 2.7 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 CDJ97708.1 - 5.3e-07 29.2 0.0 0.0045 16.3 0.0 3.2 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CDJ97708.1 - 1.3e-06 28.5 0.6 0.6 10.1 0.0 3.4 2 1 1 3 3 3 3 FAD-NAD(P)-binding Rubredoxin_C PF18267.1 CDJ97708.1 - 7.5e-06 25.8 0.0 2.4e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Rubredoxin NAD+ reductase C-terminal domain DAO PF01266.24 CDJ97708.1 - 8.7e-05 22.3 1.3 0.0017 18.0 1.3 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CDJ97708.1 - 0.005 16.0 0.3 0.088 11.9 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 CDJ97708.1 - 0.023 15.3 3.1 0.17 12.5 0.1 2.9 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase RCC1 PF00415.18 CDJ97709.1 - 6.4e-37 126.0 0.3 6.5e-08 33.1 0.0 7.9 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ97709.1 - 6.5e-27 92.7 10.9 1.5e-05 24.7 0.0 7.2 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat CopK PF11525.8 CDJ97709.1 - 0.06 13.0 0.2 0.17 11.6 0.2 1.8 1 0 0 1 1 1 0 Copper resistance protein K DUF4213 PF13938.6 CDJ97709.1 - 0.13 12.5 0.0 3.3 8.0 0.0 2.7 2 0 0 2 2 2 0 Putative heavy-metal chelation Renin_r PF07850.14 CDJ97710.1 - 1.9e-28 98.9 0.7 4.4e-28 97.8 0.7 1.6 1 0 0 1 1 1 1 Renin receptor-like protein Arc_PepC_II PF06847.11 CDJ97710.1 - 0.065 13.8 0.1 0.17 12.4 0.0 1.7 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II DUF2613 PF11021.8 CDJ97710.1 - 0.16 12.1 2.3 0.21 11.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) RVT_1 PF00078.27 CDJ97711.1 - 1.3e-33 116.4 0.0 2.4e-33 115.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LisH PF08513.11 CDJ97713.1 - 0.0055 16.6 0.3 0.009 16.0 0.3 1.4 1 0 0 1 1 1 1 LisH AAA PF00004.29 CDJ97714.1 - 1.4e-45 154.9 0.4 8.9e-31 107.1 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) Nucleolin_bd PF16725.5 CDJ97714.1 - 4e-12 45.6 0.1 9.1e-12 44.5 0.1 1.5 1 0 0 1 1 1 1 Nucleolin binding domain AAA_lid_3 PF17862.1 CDJ97714.1 - 4.1e-12 45.7 0.0 9.9e-12 44.5 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CDJ97714.1 - 7.1e-10 39.5 2.2 0.019 15.3 0.0 4.0 4 1 1 5 5 3 3 AAA ATPase domain AAA_22 PF13401.6 CDJ97714.1 - 1.5e-09 38.2 0.5 0.0042 17.4 0.0 3.5 2 1 1 3 3 3 2 AAA domain AAA_33 PF13671.6 CDJ97714.1 - 5.1e-09 36.4 0.0 0.0014 18.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain RuvB_N PF05496.12 CDJ97714.1 - 1.7e-08 34.4 0.1 0.00012 21.8 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CDJ97714.1 - 1.1e-07 31.8 0.0 0.0026 17.5 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 CDJ97714.1 - 3.4e-07 30.9 0.2 0.00043 20.8 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.14 CDJ97714.1 - 3.9e-07 30.1 0.1 0.027 14.5 0.1 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CDJ97714.1 - 6.9e-07 29.5 0.0 0.0018 18.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) NACHT PF05729.12 CDJ97714.1 - 1e-06 28.8 1.2 0.48 10.3 0.0 3.4 2 1 1 3 3 3 2 NACHT domain RNA_helicase PF00910.22 CDJ97714.1 - 1.6e-06 28.4 0.1 0.079 13.3 0.0 3.2 3 0 0 3 3 3 2 RNA helicase Mg_chelatase PF01078.21 CDJ97714.1 - 2.4e-06 27.1 0.2 0.019 14.3 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 CDJ97714.1 - 3e-06 27.3 0.1 0.0039 17.1 0.1 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain TIP49 PF06068.13 CDJ97714.1 - 6.4e-06 25.6 0.1 0.036 13.3 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain Zeta_toxin PF06414.12 CDJ97714.1 - 8.3e-06 25.2 0.2 0.0094 15.2 0.0 2.8 3 0 0 3 3 2 2 Zeta toxin AAA_28 PF13521.6 CDJ97714.1 - 2.1e-05 24.8 0.0 0.18 12.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.6 CDJ97714.1 - 6e-05 23.5 0.1 0.36 11.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_3 PF07726.11 CDJ97714.1 - 6.6e-05 22.8 0.1 0.6 10.0 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 CDJ97714.1 - 0.00011 21.7 2.3 1.1 8.6 0.0 3.7 3 1 0 4 4 4 2 KaiC AAA_25 PF13481.6 CDJ97714.1 - 0.00017 21.2 2.7 1.6 8.3 0.0 3.8 3 1 1 4 4 3 1 AAA domain TsaE PF02367.17 CDJ97714.1 - 0.00018 21.5 0.0 0.13 12.3 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Alpha-amylase PF00128.24 CDJ97714.1 - 0.00073 19.2 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Viral_helicase1 PF01443.18 CDJ97714.1 - 0.00084 19.1 0.0 0.37 10.5 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 CDJ97714.1 - 0.00093 19.7 0.1 1.6 9.2 0.1 3.1 3 0 0 3 3 2 1 ABC transporter NB-ARC PF00931.22 CDJ97714.1 - 0.0011 18.2 0.0 0.83 8.8 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain AAA_7 PF12775.7 CDJ97714.1 - 0.0012 18.4 0.0 0.7 9.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 CDJ97714.1 - 0.0024 17.6 0.1 2.2 7.9 0.0 2.8 3 0 0 3 3 3 1 Sigma-54 interaction domain PhoH PF02562.16 CDJ97714.1 - 0.007 15.8 0.2 1.8 8.0 0.1 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_24 PF13479.6 CDJ97714.1 - 0.0094 15.7 0.1 3.1 7.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 CDJ97714.1 - 0.01 15.9 0.0 5 7.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain SKI PF01202.22 CDJ97714.1 - 0.011 15.9 2.3 0.84 9.7 0.0 3.4 3 0 0 3 3 3 0 Shikimate kinase DUF3052 PF11253.8 CDJ97714.1 - 0.017 15.0 0.1 0.32 10.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3052) AAA_14 PF13173.6 CDJ97714.1 - 0.018 15.1 0.0 8.1 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CDJ97714.1 - 0.025 14.5 0.1 3.5 7.5 0.0 3.1 3 0 0 3 3 3 0 NTPase AAA_11 PF13086.6 CDJ97714.1 - 0.026 14.3 5.5 0.72 9.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 CDJ97714.1 - 0.034 13.4 0.1 2.3 7.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.17 CDJ97714.1 - 0.041 13.0 0.0 1.3 8.1 0.1 2.5 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 CDJ97714.1 - 0.056 13.4 1.0 9.7 6.0 0.0 3.1 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 CDJ97714.1 - 0.057 13.8 0.4 7.8 6.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.6 CDJ97714.1 - 0.089 12.9 0.1 21 5.2 0.0 2.9 3 0 0 3 3 2 0 Cytidylate kinase-like family PduV-EutP PF10662.9 CDJ97714.1 - 0.09 12.5 0.0 3.5 7.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IPT PF01745.16 CDJ97714.1 - 0.09 12.1 0.1 12 5.2 0.0 2.6 2 0 0 2 2 2 0 Isopentenyl transferase DUF815 PF05673.13 CDJ97714.1 - 0.12 11.6 0.0 3.2 6.8 0.0 2.8 4 0 0 4 4 2 0 Protein of unknown function (DUF815) ADK PF00406.22 CDJ97714.1 - 0.15 12.1 1.5 19 5.3 0.0 3.1 3 1 0 3 3 2 0 Adenylate kinase HEAT PF02985.22 CDJ97715.1 - 0.00048 20.1 0.4 0.05 13.9 0.1 3.4 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 CDJ97715.1 - 0.001 19.5 0.0 0.055 14.0 0.0 3.1 2 1 1 3 3 3 1 HEAT-like repeat DUF3689 PF12463.8 CDJ97715.1 - 0.041 13.2 0.0 0.083 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3689) Cnd1 PF12717.7 CDJ97715.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 CDJ97715.1 - 0.099 12.6 0.0 13 5.8 0.0 2.7 1 1 1 2 2 2 0 UME (NUC010) domain Cohesin_HEAT PF12765.7 CDJ97715.1 - 0.18 12.2 0.0 0.97 9.8 0.0 2.1 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Ion_trans PF00520.31 CDJ97716.1 - 1.9e-39 135.4 8.5 2.4e-39 135.0 8.5 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CDJ97716.1 - 1.2e-10 41.2 7.6 5e-10 39.2 7.8 2.0 1 1 1 2 2 2 2 Ion channel PKD_channel PF08016.12 CDJ97716.1 - 0.29 9.7 5.3 0.36 9.4 5.3 1.1 1 0 0 1 1 1 0 Polycystin cation channel Ion_trans PF00520.31 CDJ97717.1 - 1e-38 133.0 16.0 1.4e-38 132.5 16.0 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 CDJ97717.1 - 1.9e-27 95.4 0.0 3.4e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 CDJ97717.1 - 4.9e-13 48.8 2.5 4.9e-13 48.8 2.5 2.1 2 0 0 2 2 2 1 Ion channel Neur_chan_memb PF02932.16 CDJ97717.1 - 0.028 14.5 0.2 3.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region BTB_3 PF16017.5 CDJ97717.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.7 1 1 0 1 1 1 0 BTB/POZ domain PKD_channel PF08016.12 CDJ97717.1 - 0.4 9.3 7.7 0.52 8.9 7.7 1.2 1 0 0 1 1 1 0 Polycystin cation channel Oxidored_FMN PF00724.20 CDJ97718.1 - 0.097 11.9 0.0 0.17 11.1 0.0 1.4 1 1 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 CDJ97719.1 - 4.3e-41 141.3 0.0 5.8e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Orn_Arg_deC_N PF02784.16 CDJ97719.1 - 0.066 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain GST_N_4 PF17172.4 CDJ97720.1 - 5.4e-20 72.0 0.0 9.4e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 CDJ97720.1 - 1.8e-16 59.7 0.2 3.7e-16 58.7 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDJ97720.1 - 7.6e-09 35.5 0.1 1.5e-08 34.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDJ97720.1 - 2.7e-06 27.7 0.0 9.7e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CDJ97720.1 - 1.8e-05 24.9 0.2 4.1e-05 23.7 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDJ97720.1 - 0.00051 20.2 0.2 0.00094 19.3 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 CDJ97720.1 - 0.024 14.9 0.0 0.1 12.9 0.0 2.1 2 1 0 2 2 2 0 Glutaredoxin GST_N_4 PF17172.4 CDJ97721.1 - 1.1e-19 71.0 0.0 1.8e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 CDJ97721.1 - 3.2e-16 58.9 0.1 5.7e-16 58.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDJ97721.1 - 1e-07 31.8 0.2 2.1e-07 30.9 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDJ97721.1 - 2.8e-06 27.6 0.0 1.1e-05 25.7 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CDJ97721.1 - 1.1e-05 25.5 0.1 2.4e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDJ97721.1 - 0.0014 18.7 0.1 0.0025 18.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 CDJ97721.1 - 0.04 14.1 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 Glutaredoxin GST_N_4 PF17172.4 CDJ97722.1 - 4.7e-21 75.4 0.0 7.7e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 CDJ97722.1 - 4.2e-19 68.1 0.3 9.3e-19 67.0 0.2 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDJ97722.1 - 2.1e-10 40.5 0.0 5e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDJ97722.1 - 3.6e-07 30.5 0.0 1.3e-06 28.7 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CDJ97722.1 - 1.4e-06 28.5 0.0 3.4e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDJ97722.1 - 2e-06 27.9 0.0 4.6e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CDJ97722.1 - 0.12 12.6 0.0 1.3 9.3 0.0 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 CDJ97723.1 - 4.1e-19 69.2 0.0 6.5e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 CDJ97723.1 - 5.1e-17 61.4 0.1 1.6e-16 59.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDJ97723.1 - 3.2e-11 43.1 0.0 8e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDJ97723.1 - 1.6e-06 28.4 0.0 6.5e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CDJ97723.1 - 3.5e-06 27.1 0.0 7.6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDJ97723.1 - 1.4e-05 25.2 0.0 3.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 CDJ97723.1 - 0.14 12.4 1.2 0.51 10.6 0.1 2.6 4 1 0 4 4 4 0 Glutaredoxin GST_N_4 PF17172.4 CDJ97724.1 - 2.9e-18 66.4 0.0 4.8e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 CDJ97724.1 - 3.3e-16 58.8 0.2 6.5e-16 57.9 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDJ97724.1 - 9.4e-08 32.0 0.1 2.7e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDJ97724.1 - 2.6e-05 24.4 0.1 7.7e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDJ97724.1 - 0.00021 21.6 0.0 0.00099 19.5 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CDJ97724.1 - 0.00065 19.9 0.0 0.0034 17.5 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 CDJ97725.1 - 3.6e-19 69.3 0.0 6.4e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 CDJ97725.1 - 5.6e-18 64.5 0.1 1.1e-17 63.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDJ97725.1 - 1.7e-09 37.5 0.0 5.9e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDJ97725.1 - 2.3e-06 27.7 0.0 5.2e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDJ97725.1 - 2.1e-05 24.6 0.0 7.8e-05 22.8 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDJ97725.1 - 9.6e-05 22.7 0.0 0.00035 20.9 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 CDJ97726.1 - 6.5e-18 65.3 0.0 1.1e-17 64.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 CDJ97726.1 - 1.7e-15 56.6 0.4 7.1e-15 54.6 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDJ97726.1 - 1.5e-08 34.5 0.0 4.3e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDJ97726.1 - 1.2e-05 25.4 0.0 2.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDJ97726.1 - 0.00041 20.7 0.0 0.0011 19.3 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CDJ97726.1 - 0.0019 18.4 0.0 0.0041 17.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ost5 PF05251.12 CDJ97728.1 - 1.2e-28 99.2 2.1 1.3e-28 99.0 2.1 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 DHHC PF01529.20 CDJ97728.1 - 0.18 11.9 1.1 0.2 11.7 1.1 1.0 1 0 0 1 1 1 0 DHHC palmitoyltransferase Serinc PF03348.15 CDJ97729.1 - 4.1e-140 467.5 13.3 4.5e-140 467.4 13.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) CoA_binding_3 PF13727.6 CDJ97729.1 - 1.2 9.1 0.0 1.2 9.1 0.0 2.9 3 1 1 4 4 4 0 CoA-binding domain DUF3240 PF11582.8 CDJ97730.1 - 0.025 14.7 0.1 0.043 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3240) ZZ PF00569.17 CDJ97731.1 - 2.2e-12 46.6 4.9 2.2e-12 46.6 4.9 2.0 2 0 0 2 2 2 1 Zinc finger, ZZ type PB1 PF00564.24 CDJ97731.1 - 1e-06 28.5 0.0 2.5e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 PB1 domain SL4P PF17618.2 CDJ97731.1 - 0.00021 21.3 0.0 0.00045 20.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized Strongylid L4 protein C1_2 PF03107.16 CDJ97731.1 - 0.0037 17.5 1.0 0.0037 17.5 1.0 2.1 2 0 0 2 2 2 1 C1 domain ASPRs PF17641.2 CDJ97732.1 - 0.00023 21.4 0.0 0.00026 21.2 0.0 1.1 1 0 0 1 1 1 1 Ancylostoma-associated secreted protein related NPA PF16469.5 CDJ97733.1 - 0 1121.2 208.8 1.3e-34 119.4 16.6 12.9 12 1 1 13 13 13 13 Nematode polyprotein allergen ABA-1 VWA_3_C PF18571.1 CDJ97733.1 - 0.00057 19.7 0.1 17 5.3 0.0 5.3 5 0 0 5 5 5 1 von Willebrand factor type A C-terminal domain Lipase_GDSL_lke PF16255.5 CDJ97733.1 - 0.0059 16.0 20.7 4.9 6.4 0.5 7.6 8 0 0 8 8 8 3 GDSL-like Lipase/Acylhydrolase Pox_A_type_inc PF04508.12 CDJ97733.1 - 0.082 12.8 2.2 14 5.7 0.4 3.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Trp_repressor PF01371.19 CDJ97733.1 - 0.75 10.0 10.2 11 6.2 0.2 5.1 5 0 0 5 5 5 0 Trp repressor protein TRI5 PF06330.11 CDJ97733.1 - 0.95 8.3 40.5 1.1 8.1 0.3 8.4 9 0 0 9 9 9 0 Trichodiene synthase (TRI5) EutA PF06277.11 CDJ97733.1 - 7 5.4 23.7 11 4.7 0.1 6.9 7 0 0 7 7 7 0 Ethanolamine utilisation protein EutA Spo0A_C PF08769.11 CDJ97733.1 - 8.5 6.5 19.9 6.6 6.9 0.3 7.3 8 0 0 8 8 8 0 Sporulation initiation factor Spo0A C terminal NPA PF16469.5 CDJ97734.1 - 2.4e-09 37.8 0.0 3.2e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Nematode polyprotein allergen ABA-1 NPA PF16469.5 CDJ97735.1 - 1e-34 119.8 11.5 1.1e-19 71.3 0.0 3.8 4 0 0 4 4 4 3 Nematode polyprotein allergen ABA-1 Laminin_EGF PF00053.24 CDJ97735.1 - 7.3e-12 45.2 40.3 2.9e-08 33.7 18.3 3.4 3 0 0 3 3 3 2 Laminin EGF domain DUF3228 PF11539.8 CDJ97735.1 - 0.053 13.0 0.1 0.26 10.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3228) PcfK PF14058.6 CDJ97735.1 - 0.1 12.9 7.2 9 6.6 5.3 2.5 2 0 0 2 2 2 0 PcfK-like protein DUF1910 PF08928.10 CDJ97735.1 - 0.34 10.9 0.0 0.34 10.9 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1910) TPR_1 PF00515.28 CDJ97738.1 - 9.5e-08 31.6 5.0 0.65 9.9 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ97738.1 - 0.0002 21.6 7.2 0.078 13.3 0.1 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ97738.1 - 0.00024 21.6 5.7 0.92 10.5 0.1 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ97738.1 - 0.00028 20.8 11.9 0.89 9.8 0.1 6.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ97738.1 - 0.015 15.5 5.4 20 5.7 0.2 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ97738.1 - 0.038 14.0 0.3 7.4 6.9 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ97738.1 - 0.54 10.2 3.4 6.9 6.7 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-CCHC PF00098.23 CDJ97739.1 - 0.0012 18.8 2.0 0.0012 18.8 2.0 2.8 2 1 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.17 CDJ97739.1 - 0.041 14.1 0.4 0.072 13.4 0.0 1.6 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC_4 PF14392.6 CDJ97739.1 - 0.24 11.1 4.9 4.9 7.0 0.5 2.6 2 0 0 2 2 2 0 Zinc knuckle Peptidase_C97 PF05903.14 CDJ97740.1 - 7e-40 136.3 0.0 8.6e-40 136.0 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain RVT_1 PF00078.27 CDJ97742.1 - 3e-08 33.4 0.0 5.9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4440 PF14534.6 CDJ97743.1 - 1.6e-06 28.5 0.0 2.8e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) Ring_hydroxyl_B PF00866.18 CDJ97743.1 - 0.086 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Ring hydroxylating beta subunit rve PF00665.26 CDJ97744.1 - 1.4e-23 83.3 0.0 3.6e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ97744.1 - 2.5e-07 30.7 0.2 4.3e-07 29.9 0.2 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CDJ97744.1 - 1e-05 25.2 0.1 2.8e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 CDJ97744.1 - 0.048 13.9 0.1 0.087 13.1 0.1 1.5 1 0 0 1 1 1 0 H2C2 zinc finger NHase_beta PF02211.15 CDJ97744.1 - 0.15 12.0 0.1 1.4 8.8 0.0 2.0 2 0 0 2 2 2 0 Nitrile hydratase beta subunit RVT_1 PF00078.27 CDJ97745.1 - 4.8e-22 78.6 0.0 6.8e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CDJ97745.1 - 0.049 14.2 0.0 0.099 13.2 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease CK2S PF15011.6 CDJ97746.1 - 0.14 12.0 1.1 3.2 7.6 0.1 2.8 2 1 0 3 3 3 0 Casein Kinase 2 substrate DUF3375 PF11855.8 CDJ97746.1 - 0.3 10.0 4.3 0.21 10.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3375) Calponin PF00402.18 CDJ97747.1 - 1.4e-38 130.1 29.6 4.4e-11 42.2 0.1 6.4 6 0 0 6 6 6 6 Calponin family repeat Myc_N PF01056.18 CDJ97747.1 - 0.12 12.3 10.3 0.17 11.7 10.3 1.3 1 0 0 1 1 1 0 Myc amino-terminal region PPP4R2 PF09184.11 CDJ97747.1 - 0.87 9.1 15.6 1.4 8.5 15.6 1.3 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 CDJ97747.1 - 4.4 6.5 12.7 7.2 5.8 12.7 1.3 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 CDJ97748.1 - 3.9e-69 233.0 0.0 4.7e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ97748.1 - 1.3e-35 123.0 0.0 1.8e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ97748.1 - 0.0019 18.2 0.0 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDJ97748.1 - 0.0021 17.1 0.7 0.0032 16.4 0.7 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CDJ97748.1 - 0.015 14.6 0.2 0.025 13.9 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CDJ97748.1 - 0.022 14.3 0.0 0.074 12.6 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 CDJ97748.1 - 0.028 13.8 0.0 0.056 12.8 0.0 1.5 1 0 0 1 1 1 0 Kinase-like NDUF_B4 PF07225.12 CDJ97748.1 - 0.077 12.9 0.1 0.31 10.9 0.1 1.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Pkinase_fungal PF17667.1 CDJ97748.1 - 0.16 10.7 0.8 1.2 7.8 0.1 1.9 1 1 1 2 2 2 0 Fungal protein kinase Pkinase PF00069.25 CDJ97749.1 - 1.7e-15 57.1 0.1 1.9e-15 57.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ97749.1 - 5.9e-09 35.6 0.1 6.9e-09 35.4 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Ldl_recept_b PF00058.17 CDJ97750.1 - 1.6e-37 127.7 2.8 3.9e-12 46.4 0.0 5.9 6 0 0 6 6 6 5 Low-density lipoprotein receptor repeat class B Ldl_recept_a PF00057.18 CDJ97750.1 - 1.3e-16 60.5 27.9 4.7e-12 45.9 9.0 5.3 5 1 1 6 6 6 2 Low-density lipoprotein receptor domain class A EGF_CA PF07645.15 CDJ97750.1 - 7.6e-09 35.6 5.6 7.6e-09 35.6 5.6 6.2 3 2 1 4 4 4 1 Calcium-binding EGF domain FXa_inhibition PF14670.6 CDJ97750.1 - 5.1e-06 26.7 8.0 5.1e-06 26.7 8.0 5.7 4 1 1 5 5 5 2 Coagulation Factor Xa inhibitory site SGL PF08450.12 CDJ97750.1 - 7.1e-06 25.8 0.9 0.016 14.8 0.9 3.4 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region cEGF PF12662.7 CDJ97750.1 - 0.00014 21.8 20.8 0.00022 21.1 0.4 4.3 4 0 0 4 4 4 2 Complement Clr-like EGF-like Arylesterase PF01731.20 CDJ97750.1 - 0.082 13.1 0.0 1.4 9.1 0.0 2.9 3 0 0 3 3 3 0 Arylesterase DUF5050 PF16472.5 CDJ97750.1 - 0.12 11.6 0.0 0.65 9.2 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5050) PAP2_C PF14360.6 CDJ97751.1 - 6.1e-22 78.0 3.4 6.1e-22 78.0 3.4 2.7 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2 PF01569.21 CDJ97751.1 - 1.4e-07 31.3 5.9 1.4e-07 31.3 5.9 1.8 2 0 0 2 2 2 1 PAP2 superfamily Jiv90 PF14901.6 CDJ97752.1 - 1.3e-34 118.2 5.7 4.6e-34 116.5 5.7 2.0 1 0 0 1 1 1 1 Cleavage inducing molecular chaperone DnaJ PF00226.31 CDJ97752.1 - 6.3e-14 51.9 0.0 2.2e-13 50.1 0.0 2.0 1 0 0 1 1 1 1 DnaJ domain ABC2_membrane PF01061.24 CDJ97753.1 - 0.0083 15.6 7.0 0.011 15.2 7.0 1.1 1 0 0 1 1 1 1 ABC-2 type transporter DPM3 PF08285.11 CDJ97753.1 - 0.12 12.6 2.6 0.18 12.0 2.6 1.3 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) ABC_tran PF00005.27 CDJ97754.1 - 2.3e-10 41.1 0.0 3.7e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter MVL PF12151.8 CDJ97755.1 - 0.036 13.9 1.1 0.075 12.9 1.1 1.5 1 0 0 1 1 1 0 Mannan-binding protein Solute_trans_a PF03619.16 CDJ97756.1 - 1.2e-23 84.0 19.0 1.5e-23 83.6 19.0 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Mito_carr PF00153.27 CDJ97757.1 - 1.2e-53 179.0 2.5 3.5e-18 65.3 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein PPV_E1_C PF00519.17 CDJ97757.1 - 0.004 16.1 0.0 0.0058 15.5 0.0 1.1 1 0 0 1 1 1 1 Papillomavirus helicase TC1 PF15063.6 CDJ97757.1 - 0.22 11.4 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Thyroid cancer protein 1 Kunitz_BPTI PF00014.23 CDJ97759.1 - 3.6e-57 190.4 36.1 9.7e-18 64.2 7.4 5.4 4 0 0 4 4 4 4 Kunitz/Bovine pancreatic trypsin inhibitor domain Lustrin_cystein PF14625.6 CDJ97759.1 - 8.7e-34 115.6 106.8 4e-08 33.5 5.6 9.8 9 1 0 9 9 9 6 Lustrin, cysteine-rich repeated domain EB PF01683.18 CDJ97759.1 - 4.2e-09 36.5 12.9 4.2e-09 36.5 12.9 8.2 6 3 1 7 7 7 2 EB module Acetyltransf_3 PF13302.7 CDJ97761.1 - 3.6e-06 27.7 0.0 4e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-CDGSH PF09360.10 CDJ97762.1 - 2.1e-18 66.2 1.3 1.4e-09 38.0 0.1 2.3 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type TFIIS_C PF01096.18 CDJ97763.1 - 2.4e-20 72.1 3.5 2.4e-20 72.1 3.5 2.9 2 1 0 2 2 1 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CDJ97763.1 - 1.4e-05 24.9 5.3 1.4e-05 24.9 5.3 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 CDJ97763.1 - 0.00052 19.9 12.8 0.0019 18.1 0.7 2.8 2 2 1 3 3 3 2 Transposase zinc-ribbon domain Nudix_N_2 PF14803.6 CDJ97763.1 - 0.013 15.4 5.2 0.013 15.4 5.2 2.4 2 0 0 2 2 2 0 Nudix N-terminal zf-ribbon_3 PF13248.6 CDJ97763.1 - 0.014 14.8 11.1 0.022 14.2 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain PH_17 PF18012.1 CDJ97763.1 - 0.045 13.5 0.1 0.071 12.8 0.1 1.4 1 0 0 1 1 1 0 PH domain zf-NADH-PPase PF09297.11 CDJ97763.1 - 0.46 10.2 11.0 0.17 11.5 4.8 2.6 2 1 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain VP_N-CPKC PF11475.8 CDJ97763.1 - 0.48 10.4 0.1 0.48 10.4 0.1 3.3 3 1 1 4 4 4 0 Virion protein N terminal domain Lar_restr_allev PF14354.6 CDJ97763.1 - 0.52 10.7 9.4 3.1 8.3 3.0 2.3 2 0 0 2 2 2 0 Restriction alleviation protein Lar DNA_ligase_ZBD PF03119.16 CDJ97763.1 - 0.98 9.5 0.1 0.98 9.5 0.1 4.4 5 0 0 5 5 4 0 NAD-dependent DNA ligase C4 zinc finger domain zf-RING_7 PF02591.15 CDJ97763.1 - 1.4 9.2 0.2 1.4 9.2 0.2 3.3 3 1 0 3 3 3 0 C4-type zinc ribbon domain TF_Zn_Ribbon PF08271.12 CDJ97763.1 - 1.5 8.4 12.8 0.56 9.8 0.2 3.4 2 1 0 2 2 2 0 TFIIB zinc-binding HypA PF01155.19 CDJ97763.1 - 2.4 8.2 6.0 30 4.7 3.7 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 CDJ97763.1 - 2.7 8.1 9.4 11 6.1 4.1 2.5 2 1 0 2 2 2 0 zinc-ribbons zf-Di19 PF05605.12 CDJ97763.1 - 3.2 8.1 0.1 3.2 8.1 0.1 3.5 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_4 PF13717.6 CDJ97763.1 - 4.5 7.3 13.5 3.9 7.5 0.4 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zf_C2H2_10 PF18414.1 CDJ97763.1 - 5 6.8 14.6 4.2 7.0 4.3 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger zf-H2C2_2 PF13465.6 CDJ97763.1 - 9.5 6.8 8.7 54 4.5 0.9 3.4 3 0 0 3 3 3 0 Zinc-finger double domain GLTP PF08718.11 CDJ97764.1 - 1.5e-37 129.2 0.1 6e-37 127.2 0.0 2.0 2 1 0 2 2 2 1 Glycolipid transfer protein (GLTP) ATP-synt_C PF00137.21 CDJ97765.1 - 3.6e-10 40.0 11.6 5.1e-10 39.5 11.6 1.2 1 0 0 1 1 1 1 ATP synthase subunit C NolX PF05819.11 CDJ97765.1 - 0.42 9.9 0.8 0.5 9.6 0.8 1.0 1 0 0 1 1 1 0 NolX protein DSPc PF00782.20 CDJ97766.1 - 2.9e-30 104.8 0.1 4.9e-30 104.1 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DEK_C PF08766.11 CDJ97766.1 - 4.3e-13 49.0 0.6 1e-12 47.8 0.6 1.7 1 0 0 1 1 1 1 DEK C terminal domain Alpha-2-MRAP_N PF06400.11 CDJ97766.1 - 0.0095 15.9 0.7 0.024 14.6 0.7 1.6 1 0 0 1 1 1 1 Alpha-2-macroglobulin RAP, N-terminal domain Y_phosphatase PF00102.27 CDJ97766.1 - 0.02 14.4 0.2 0.063 12.8 0.2 1.8 1 1 0 1 1 1 0 Protein-tyrosine phosphatase HBS1_N PF08938.10 CDJ97766.1 - 0.36 11.2 3.2 4.9 7.5 3.0 2.3 2 0 0 2 2 2 0 HBS1 N-terminus Asn_synthase PF00733.21 CDJ97768.1 - 3.5e-83 280.2 0.1 2.5e-47 162.3 0.0 2.9 2 1 1 3 3 3 2 Asparagine synthase GATase_7 PF13537.6 CDJ97768.1 - 9.1e-22 77.3 0.0 1.8e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CDJ97768.1 - 9.4e-17 61.5 0.0 1.7e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF851 PF05867.11 CDJ97768.1 - 3e-07 30.2 0.3 3e-07 30.2 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF851) DUF3700 PF12481.8 CDJ97768.1 - 7.8e-05 22.2 0.0 0.00024 20.6 0.0 1.8 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 CDJ97768.1 - 0.00032 19.9 0.0 0.00079 18.6 0.0 1.6 1 0 0 1 1 1 1 NAD synthase QueC PF06508.13 CDJ97768.1 - 0.021 14.3 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC APH PF01636.23 CDJ97769.1 - 2.8e-45 155.1 0.0 5.3e-45 154.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.24 CDJ97769.1 - 3.4e-36 124.7 0.3 5.6e-36 124.0 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CDJ97769.1 - 1.4e-17 63.6 0.0 3.4e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CDJ97769.1 - 2.4e-12 47.3 0.5 4.3e-12 46.5 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CDJ97769.1 - 1.6e-11 44.9 0.0 3.6e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HAD_2 PF13419.6 CDJ97769.1 - 6.3e-11 42.7 0.0 5.5e-10 39.6 0.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDJ97769.1 - 1.7e-10 41.6 0.0 1.1e-08 35.7 0.0 3.4 2 2 0 2 2 2 1 haloacid dehalogenase-like hydrolase RIO1 PF01163.22 CDJ97769.1 - 0.00011 21.9 0.3 0.14 11.7 0.0 2.4 2 0 0 2 2 2 2 RIO1 family EcKinase PF02958.20 CDJ97769.1 - 0.00012 21.5 0.0 0.00025 20.5 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase Hydrolase_6 PF13344.6 CDJ97769.1 - 0.0075 16.4 0.0 0.12 12.5 0.0 2.8 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Choline_kinase PF01633.20 CDJ97769.1 - 0.011 15.3 0.1 0.023 14.3 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase SHOCT PF09851.9 CDJ97769.1 - 0.089 12.6 1.1 0.65 9.8 0.5 2.5 2 0 0 2 2 2 0 Short C-terminal domain DUF1679 PF07914.11 CDJ97769.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) PDZ_6 PF17820.1 CDJ97770.1 - 1.1e-10 41.2 0.0 0.00013 21.7 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 CDJ97770.1 - 2.1e-10 40.8 0.0 0.00037 20.8 0.0 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CDJ97770.1 - 1.5e-08 34.8 0.1 0.00057 20.2 0.0 2.2 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 CDJ97770.1 - 3.1e-06 27.1 0.0 0.0064 16.4 0.0 2.5 2 0 0 2 2 2 2 Tricorn protease PDZ domain PDZ_4 PF17816.1 CDJ97770.1 - 0.0081 16.6 0.1 0.13 12.7 0.0 2.2 2 0 0 2 2 2 1 PDZ domain G_glu_transpept PF01019.21 CDJ97771.1 - 9.9e-166 552.5 0.0 1.1e-165 552.3 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase G_glu_transpept PF01019.21 CDJ97772.1 - 2e-25 89.6 0.0 2.2e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Piezo_RRas_bdg PF12166.8 CDJ97773.1 - 9.3e-108 361.2 0.5 1.5e-107 360.6 0.5 1.3 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain PIEZO PF15917.5 CDJ97773.1 - 4.6e-45 153.9 3.2 4.1e-38 131.1 2.6 2.3 1 1 1 2 2 2 2 Piezo Amidase PF01425.21 CDJ97773.1 - 0.021 13.8 0.1 0.039 12.9 0.1 1.3 1 0 0 1 1 1 0 Amidase DUF5496 PF17600.2 CDJ97773.1 - 0.1 12.6 1.2 0.65 10.1 0.0 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5496) Wzy_C PF04932.15 CDJ97773.1 - 0.31 10.7 0.0 0.31 10.7 0.0 5.3 6 1 0 6 6 6 0 O-Antigen ligase UPF0242 PF06785.11 CDJ97774.1 - 0.01 15.9 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Pam17 PF08566.10 CDJ97774.1 - 0.015 15.2 0.1 0.02 14.8 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 HALZ PF02183.18 CDJ97774.1 - 0.063 13.5 1.0 0.1 12.9 1.0 1.2 1 0 0 1 1 1 0 Homeobox associated leucine zipper Ntox8 PF15545.6 CDJ97774.1 - 0.12 12.5 1.9 1 9.5 0.1 2.5 1 1 2 3 3 3 0 Bacterial toxin 8 WD40 PF00400.32 CDJ97775.1 - 0.013 16.3 0.3 1.2 10.1 0.4 3.1 2 0 0 2 2 2 0 WD domain, G-beta repeat YbhQ PF11076.8 CDJ97776.1 - 0.054 13.5 0.3 0.11 12.5 0.1 1.6 1 1 1 2 2 2 0 Putative inner membrane protein YbhQ 7TM_GPCR_Srv PF10323.9 CDJ97777.1 - 2.9e-10 40.0 0.9 3.6e-10 39.7 0.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv IN_DBD_C PF00552.21 CDJ97778.1 - 3.3 7.1 10.0 29 4.0 0.2 4.3 5 0 0 5 5 5 0 Integrase DNA binding domain IN_DBD_C PF00552.21 CDJ97779.1 - 0.12 11.6 9.9 23 4.4 0.1 4.9 5 0 0 5 5 5 0 Integrase DNA binding domain CRAL_TRIO PF00650.20 CDJ97780.1 - 9.9e-21 74.1 0.2 1.2e-20 73.9 0.2 1.0 1 0 0 1 1 1 1 CRAL/TRIO domain zf-CXXC PF02008.20 CDJ97781.1 - 1.3e-16 60.3 41.9 5.5e-12 45.5 21.0 2.4 2 0 0 2 2 2 2 CXXC zinc finger domain DUF3040 PF11239.8 CDJ97781.1 - 0.2 11.9 0.0 0.38 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF2423 PF10338.9 CDJ97782.1 - 0.012 15.8 0.2 0.022 15.0 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2423) RPE65 PF03055.15 CDJ97783.1 - 2.4e-38 132.5 0.0 2.9e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein AlbA_2 PF04326.14 CDJ97784.1 - 6.5e-15 55.6 0.0 8.7e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Putative DNA-binding domain VWA PF00092.28 CDJ97785.1 - 1.2e-19 71.2 0.0 1.9e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Lectin_C PF00059.21 CDJ97785.1 - 7.5e-13 49.2 0.0 2.6e-12 47.4 0.0 1.9 1 0 0 1 1 1 1 Lectin C-type domain VWA_2 PF13519.6 CDJ97785.1 - 3.4e-09 37.3 0.1 9.8e-09 35.8 0.1 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain Lectin_C PF00059.21 CDJ97786.1 - 6.6e-16 59.0 1.4 6.6e-16 59.0 1.4 1.7 2 0 0 2 2 2 1 Lectin C-type domain Wax2_C PF12076.8 CDJ97786.1 - 0.012 15.3 0.2 0.58 9.8 0.0 2.1 1 1 1 2 2 2 0 WAX2 C-terminal domain TIL PF01826.17 CDJ97786.1 - 1.6 9.1 8.3 4.6 7.6 0.5 2.5 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain RhoGAP PF00620.27 CDJ97787.1 - 3.2e-16 59.5 0.0 4.8e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Paf67 PF10255.9 CDJ97790.1 - 5.8e-139 463.6 0.8 7.3e-139 463.2 0.8 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 DUF368 PF04018.13 CDJ97790.1 - 0.066 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF368) DUF3384 PF11864.8 CDJ97790.1 - 0.12 11.3 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) MgtE PF01769.16 CDJ97791.1 - 6.5e-35 120.2 11.5 2.8e-18 66.5 4.3 3.6 3 1 1 4 4 4 2 Divalent cation transporter Cpn60_TCP1 PF00118.24 CDJ97792.1 - 4e-158 527.1 15.9 4.6e-158 526.9 15.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 CDJ97792.1 - 0.018 14.6 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 Telomere recombination SCAB_CC PF16712.5 CDJ97792.1 - 0.2 11.5 4.6 0.24 11.2 0.5 2.3 2 0 0 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein DIX PF00778.17 CDJ97793.1 - 1.6e-20 72.7 0.2 2.9e-20 71.9 0.2 1.4 1 0 0 1 1 1 1 DIX domain DEP PF00610.21 CDJ97793.1 - 6.2e-17 61.4 0.1 1.3e-16 60.4 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ PF00595.24 CDJ97793.1 - 4.3e-14 52.6 0.0 7.7e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDJ97793.1 - 1.5e-06 27.9 0.2 3.2e-06 26.9 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ97793.1 - 0.00011 22.4 0.0 0.00025 21.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Dishevelled PF02377.15 CDJ97793.1 - 2 8.8 10.9 0.068 13.6 2.4 2.3 2 0 0 2 2 2 0 Dishevelled specific domain DSPc PF00782.20 CDJ97794.1 - 1.6e-41 141.3 0.0 2.4e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 CDJ97794.1 - 0.00068 20.1 0.0 0.0029 18.1 0.0 2.1 2 1 0 2 2 2 1 Rhodanese-like domain PTPlike_phytase PF14566.6 CDJ97794.1 - 0.078 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 CDJ97794.1 - 0.096 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase OTU PF02338.19 CDJ97795.1 - 4.2e-23 82.2 0.1 1.2e-22 80.8 0.0 1.8 2 1 0 2 2 2 1 OTU-like cysteine protease IHABP4_N PF16174.5 CDJ97795.1 - 0.0077 16.8 13.0 0.015 15.9 13.0 1.4 1 0 0 1 1 1 1 Intracellular hyaluronan-binding protein 4 N-terminal SR-25 PF10500.9 CDJ97795.1 - 0.85 9.2 21.5 2 8.0 20.3 1.9 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Taq-exonuc PF09281.10 CDJ97795.1 - 2.9 7.9 5.4 0.89 9.6 0.1 2.7 3 1 1 4 4 4 0 Taq polymerase, exonuclease DUF667 PF05018.13 CDJ97796.1 - 1.1e-91 305.6 0.4 1.3e-91 305.4 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) SAM_1 PF00536.30 CDJ97797.1 - 0.00038 20.8 0.0 0.00076 19.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-Di19 PF05605.12 CDJ97798.1 - 1e-06 28.9 0.9 9.6e-06 25.8 0.1 2.6 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 CDJ97798.1 - 2.6e-05 24.7 6.5 0.087 13.7 0.7 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CDJ97798.1 - 0.00037 20.8 1.5 0.004 17.5 1.0 4.3 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 CDJ97798.1 - 0.012 16.2 1.2 1.7 9.3 0.6 2.8 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 CDJ97798.1 - 0.049 14.0 4.6 3.1 8.2 0.7 2.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 CDJ97798.1 - 0.46 10.3 5.1 0.22 11.3 0.3 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type WD40 PF00400.32 CDJ97799.1 - 1.1e-24 86.2 16.4 5.2e-06 27.1 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ97799.1 - 2.7e-18 66.0 3.8 1e-07 32.2 0.6 4.3 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDJ97799.1 - 3.6e-06 27.0 0.1 0.19 11.6 0.0 3.4 1 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CDJ97799.1 - 0.043 12.5 0.1 0.043 12.5 0.1 1.7 2 0 0 2 2 2 0 Nucleoporin Nup120/160 WD40 PF00400.32 CDJ97800.1 - 1.4e-08 35.2 9.8 0.00057 20.6 0.0 5.0 5 1 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.6 CDJ97800.1 - 0.0043 17.5 0.1 8.4 7.0 0.0 3.9 3 0 0 3 3 3 2 PQQ-like domain PQQ_2 PF13360.6 CDJ97800.1 - 0.094 12.3 0.0 0.31 10.6 0.0 1.7 1 1 0 1 1 1 0 PQQ-like domain DUF3149 PF11346.8 CDJ97801.1 - 2.7e-05 23.7 0.2 4e-05 23.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3149) DUF1218 PF06749.12 CDJ97801.1 - 0.024 15.2 0.2 0.035 14.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1218) OAD_gamma PF04277.13 CDJ97801.1 - 0.028 15.0 0.0 0.039 14.6 0.0 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Saf_2TM PF18303.1 CDJ97801.1 - 0.031 13.9 0.4 0.044 13.4 0.4 1.2 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DUF4381 PF14316.6 CDJ97801.1 - 0.034 14.4 0.2 0.05 13.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF3328 PF11807.8 CDJ97801.1 - 0.057 13.2 0.1 0.082 12.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Phage_Gp23 PF10669.9 CDJ97801.1 - 0.064 13.6 0.3 0.094 13.0 0.3 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) MscL PF01741.18 CDJ97801.1 - 0.095 13.0 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL DUF2207 PF09972.9 CDJ97801.1 - 0.11 11.2 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SieB PF14163.6 CDJ97801.1 - 0.12 11.9 0.5 0.2 11.1 0.5 1.3 1 0 0 1 1 1 0 Super-infection exclusion protein B Orf78 PF06024.12 CDJ97801.1 - 0.14 12.5 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 Orf78 (ac78) Sigma_reg_N PF13800.6 CDJ97801.1 - 0.19 12.0 0.1 0.32 11.3 0.1 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Vpu PF00558.19 CDJ97801.1 - 0.43 10.4 3.3 0.7 9.7 3.3 1.2 1 0 0 1 1 1 0 Vpu protein BTB PF00651.31 CDJ97803.1 - 4e-05 23.8 0.1 8e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain I-set PF07679.16 CDJ97805.1 - 2.7e-19 69.0 0.0 7.6e-10 38.7 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ97805.1 - 2e-18 66.8 0.2 1.7e-08 34.9 0.1 3.2 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 CDJ97805.1 - 1.7e-16 60.2 0.1 3.7e-06 27.0 0.1 3.2 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 CDJ97805.1 - 2.2e-14 53.6 0.6 1.7e-07 31.5 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 CDJ97805.1 - 3.5e-07 30.4 2.9 0.016 15.4 0.0 3.5 3 1 1 4 4 4 2 Immunoglobulin V-set domain Ig_6 PF18452.1 CDJ97805.1 - 4.5e-07 29.3 0.0 0.016 14.8 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_4 PF16680.5 CDJ97805.1 - 0.0061 16.8 0.5 0.11 12.8 0.0 2.7 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 CDJ97805.1 - 0.01 15.9 0.9 0.1 12.7 0.0 2.8 3 1 0 3 3 3 1 C17orf99 Ig domain zf-RRN7 PF11781.8 CDJ97805.1 - 0.084 12.6 0.2 13 5.6 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Peptidase_A17 PF05380.13 CDJ97806.1 - 1.6e-37 129.0 0.1 3.1e-37 128.1 0.1 1.5 1 0 0 1 1 1 1 Pao retrotransposon peptidase RVT_1 PF00078.27 CDJ97806.1 - 5.1e-07 29.4 0.0 9.4e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LydB PF16084.5 CDJ97806.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 LydA-holin antagonist I-set PF07679.16 CDJ97807.1 - 3.7e-47 158.3 0.0 3.9e-15 55.7 0.0 4.1 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ97807.1 - 4.6e-47 158.5 0.1 2.5e-13 50.4 0.0 4.1 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 CDJ97807.1 - 4.7e-34 116.6 0.0 9.3e-10 38.7 0.1 4.1 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 CDJ97807.1 - 1.6e-29 101.9 0.0 1.6e-08 34.6 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 CDJ97807.1 - 1.6e-16 60.5 1.6 0.095 12.9 0.0 7.0 4 3 1 6 6 6 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDJ97807.1 - 2.6e-15 56.2 0.2 0.00025 21.0 0.0 3.5 3 1 0 3 3 3 3 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 CDJ97807.1 - 0.00093 18.7 0.0 0.63 9.6 0.0 3.6 4 0 0 4 4 4 1 Immunoglobulin domain Izumo-Ig PF16706.5 CDJ97807.1 - 0.0012 18.9 0.1 0.58 10.3 0.0 3.9 4 1 0 4 4 4 1 Izumo-like Immunoglobulin domain FLYWCH PF04500.16 CDJ97807.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.7 1 0 0 1 1 1 0 FLYWCH zinc finger domain DUF1082 PF06449.11 CDJ97808.1 - 0.005 16.6 0.1 0.0058 16.4 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1082) tRNA_U5-meth_tr PF05958.11 CDJ97808.1 - 0.047 12.7 0.0 0.051 12.6 0.0 1.0 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase BRX PF08381.11 CDJ97810.1 - 0.058 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 Adap_comp_sub PF00928.21 CDJ97811.1 - 4.1e-75 252.6 0.1 5.9e-75 252.0 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family TM2 PF05154.16 CDJ97811.1 - 2.9e-10 40.3 8.8 5.1e-10 39.5 8.8 1.4 1 0 0 1 1 1 1 TM2 domain Clat_adaptor_s PF01217.20 CDJ97811.1 - 8.1e-07 29.1 0.2 1.7e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Clathrin adaptor complex small chain MMR_HSR1_Xtn PF16897.5 CDJ97812.1 - 2e-44 149.9 0.9 4.2e-44 148.9 0.9 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CDJ97812.1 - 1.3e-22 79.6 0.1 2.5e-22 78.7 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CDJ97812.1 - 1.3e-20 73.6 0.0 2.4e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ97812.1 - 1.7e-11 43.9 0.0 2.8e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CDJ97812.1 - 0.0031 17.6 0.3 0.3 11.1 0.0 2.3 1 1 0 2 2 2 1 Dynamin family SafA PF17073.5 CDJ97812.1 - 0.049 13.6 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Two-component-system connector protein MeaB PF03308.16 CDJ97812.1 - 0.057 12.4 1.5 0.18 10.7 0.1 2.3 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CREPT PF16566.5 CDJ97813.1 - 5e-33 114.3 4.4 3.4e-32 111.7 5.0 2.0 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour CTD_bind PF04818.13 CDJ97813.1 - 3.9e-16 59.6 1.0 7.6e-15 55.5 0.1 3.2 4 1 0 4 4 4 1 RNA polymerase II-binding domain. DUF445 PF04286.12 CDJ97813.1 - 0.016 15.0 1.5 0.05 13.4 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF445) CDH1_2_SANT_HL1 PF18375.1 CDJ97813.1 - 0.13 12.9 0.7 0.33 11.7 0.6 1.8 1 1 0 1 1 1 0 CDH1/2 SANT-Helical linker 1 TMF_DNA_bd PF12329.8 CDJ97813.1 - 0.19 11.8 2.1 0.39 10.7 0.3 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding MSA-2c PF12238.8 CDJ97813.1 - 0.3 11.1 0.1 0.3 11.1 0.1 1.9 2 1 0 2 2 2 0 Merozoite surface antigen 2c LEM PF03020.15 CDJ97815.1 - 1.2e-17 63.1 0.2 3e-17 61.9 0.2 1.7 1 0 0 1 1 1 1 LEM domain MSC PF09402.10 CDJ97815.1 - 3.1e-07 30.2 0.0 4.8e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain Vma12 PF11712.8 CDJ97815.1 - 0.079 13.0 0.1 0.079 13.0 0.1 1.9 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase 7tm_1 PF00001.21 CDJ97816.1 - 1.4e-09 37.7 13.7 1.4e-09 37.7 13.7 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) CortBP2 PF09727.9 CDJ97817.1 - 7e-57 192.4 21.2 7e-57 192.4 21.2 1.7 2 0 0 2 2 2 1 Cortactin-binding protein-2 DUF3564 PF12087.8 CDJ97817.1 - 0.2 11.6 1.4 2.1 8.3 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3564) BssS PF13991.6 CDJ97818.1 - 0.039 14.0 0.0 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 BssS protein family BAG6 PF12057.8 CDJ97819.1 - 0.0016 18.1 0.8 21 4.8 0.0 4.2 5 0 0 5 5 5 2 BCL2-associated athanogene 6 DUF3010 PF11215.8 CDJ97819.1 - 0.0073 16.6 16.2 2.4 8.5 0.1 6.1 7 0 0 7 7 7 3 Protein of unknown function (DUF3010) Ribosomal_L23 PF00276.20 CDJ97819.1 - 0.014 15.7 13.2 5.6 7.4 0.2 5.6 5 0 0 5 5 5 0 Ribosomal protein L23 EcoEI_R_C PF08463.10 CDJ97819.1 - 0.057 13.5 0.1 28 4.8 0.0 4.2 4 0 0 4 4 4 0 EcoEI R protein C-terminal DUF1759 PF03564.15 CDJ97820.1 - 3.4e-24 85.5 1.9 4.5e-24 85.1 0.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) RVT_1 PF00078.27 CDJ97822.1 - 1.6e-29 103.0 0.0 3.3e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MAP17 PF15807.5 CDJ97822.1 - 0.014 15.6 0.6 0.057 13.7 0.6 2.0 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 AC_N PF16214.5 CDJ97822.1 - 2 7.4 7.6 3.3 6.7 7.6 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region ECSCR PF15820.5 CDJ97822.1 - 7.2 6.5 6.9 4 7.3 3.3 2.3 1 1 1 2 2 2 0 Endothelial cell-specific chemotaxis regulator RVT_1 PF00078.27 CDJ97823.1 - 1.7e-31 109.4 0.0 3.5e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Spectrin PF00435.21 CDJ97824.1 - 5.8e-05 23.5 0.6 5.8e-05 23.5 0.6 1.9 2 0 0 2 2 2 1 Spectrin repeat DUF1525 PF07511.11 CDJ97824.1 - 0.11 12.7 0.9 0.13 12.4 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) DUF883 PF05957.13 CDJ97824.1 - 3.6 8.2 7.7 16 6.2 0.9 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Defensin_int PF17858.1 CDJ97825.1 - 4.4 7.4 5.9 24 5.0 0.5 2.4 2 0 0 2 2 2 0 Platypus intermediate defensin-like peptide DSPc PF00782.20 CDJ97826.1 - 5.1e-31 107.2 0.1 7.2e-31 106.8 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDJ97826.1 - 4.4e-05 23.2 0.0 6.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 CDJ97826.1 - 0.037 13.7 0.1 0.057 13.1 0.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 CDJ97826.1 - 0.037 14.1 0.0 0.06 13.5 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate S1 PF00575.23 CDJ97827.1 - 4.6e-23 81.4 20.9 6e-05 23.3 0.0 11.5 12 1 0 12 12 12 5 S1 RNA binding domain Suf PF05843.14 CDJ97827.1 - 2.6e-13 50.6 8.2 0.00011 22.3 0.0 4.2 1 1 3 4 4 4 3 Suppressor of forked protein (Suf) TPR_19 PF14559.6 CDJ97827.1 - 5.3e-12 46.1 0.0 0.016 15.7 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ97827.1 - 1.8e-10 41.3 0.0 0.03 15.0 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ97827.1 - 1.6e-07 31.5 4.0 0.92 10.5 0.0 5.1 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ97827.1 - 0.0074 16.6 0.2 4.7 7.8 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ97827.1 - 0.024 15.2 3.7 8.5 7.3 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ97827.1 - 0.026 14.6 0.2 37 4.8 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ97827.1 - 0.029 14.6 0.0 0.33 11.2 0.0 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 CDJ97827.1 - 0.046 12.9 1.7 0.71 9.0 1.1 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ97827.1 - 0.056 13.7 1.1 84 3.6 0.1 4.0 3 1 0 4 4 4 0 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 CDJ97827.1 - 0.19 11.7 9.5 1.5 8.9 1.2 4.7 4 0 0 4 4 4 0 RNase II-type exonuclease C-terminal S1 domain NRDE-2 PF08424.10 CDJ97827.1 - 0.21 10.6 4.5 0.22 10.6 0.2 2.8 2 1 1 3 3 3 0 NRDE-2, necessary for RNA interference PRORP PF16953.5 CDJ97827.1 - 1.4 8.4 4.3 5.1 6.5 0.2 2.6 2 1 0 2 2 2 0 Protein-only RNase P dCMP_cyt_deam_1 PF00383.23 CDJ97828.1 - 3.3e-22 78.3 1.8 4.4e-22 77.9 1.8 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CDJ97828.1 - 1e-20 73.9 0.0 1.2e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 CDJ97828.1 - 0.00089 19.4 0.5 0.0014 18.7 0.5 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 CDJ97828.1 - 0.017 15.2 0.2 0.03 14.4 0.2 1.4 1 0 0 1 1 1 0 APOBEC2 NAD2 PF18782.1 CDJ97828.1 - 0.044 13.9 0.1 0.074 13.1 0.1 1.3 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 GA PF01468.17 CDJ97829.1 - 0.052 13.8 0.5 0.08 13.2 0.5 1.4 1 1 0 1 1 1 0 GA module Peptidase_M8 PF01457.16 CDJ97831.1 - 4.8e-49 167.4 3.8 7.7e-49 166.8 3.8 1.2 1 0 0 1 1 1 1 Leishmanolysin Helitron_like_N PF14214.6 CDJ97833.1 - 2.3e-59 200.8 0.0 3.7e-59 200.1 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.13 CDJ97833.1 - 0.0024 17.0 0.0 0.0034 16.5 0.0 1.2 1 0 0 1 1 1 1 Bacteriophage replication gene A protein (GPA) BCMA-Tall_bind PF09257.10 CDJ97833.1 - 0.065 13.3 0.6 0.19 11.9 0.6 1.8 1 0 0 1 1 1 0 BCMA, TALL-1 binding Peptidase_M8 PF01457.16 CDJ97834.1 - 3e-37 128.5 6.0 3.6e-37 128.3 6.0 1.0 1 0 0 1 1 1 1 Leishmanolysin ubiquitin PF00240.23 CDJ97835.1 - 9.1e-33 111.8 0.0 4.2e-20 71.3 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 CDJ97835.1 - 3e-15 55.8 0.0 4.5e-07 29.6 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like zf-RING_UBOX PF13445.6 CDJ97835.1 - 2.4e-07 30.6 7.8 5.7e-07 29.5 7.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDJ97835.1 - 1.4e-05 24.8 8.3 2.8e-05 23.9 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ97835.1 - 6e-05 22.8 5.8 0.00011 22.0 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ97835.1 - 0.00017 21.4 8.3 0.00041 20.1 8.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ97835.1 - 0.00019 21.7 7.0 0.00044 20.5 7.0 1.6 1 0 0 1 1 1 1 Ring finger domain Ubiquitin_4 PF18036.1 CDJ97835.1 - 0.00065 19.7 0.0 2.1 8.4 0.0 3.3 3 0 0 3 3 3 1 Ubiquitin-like domain zf-C3HC4_4 PF15227.6 CDJ97835.1 - 0.0011 19.0 8.3 0.0025 17.9 8.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CDJ97835.1 - 0.0016 18.2 7.0 0.0032 17.3 7.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Ubiquitin_5 PF18037.1 CDJ97835.1 - 0.016 15.5 0.0 0.039 14.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain zf-RING_5 PF14634.6 CDJ97835.1 - 0.016 15.1 8.0 0.038 13.9 8.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_6 PF14835.6 CDJ97835.1 - 0.02 14.7 2.8 0.045 13.6 2.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Ubiquitin_2 PF14560.6 CDJ97835.1 - 0.023 15.2 0.1 0.24 11.9 0.0 2.6 2 1 0 2 2 2 0 Ubiquitin-like domain zf-RING_11 PF17123.5 CDJ97835.1 - 1 9.1 8.3 3.3 7.5 8.3 1.9 1 1 0 1 1 1 0 RING-like zinc finger ubiquitin PF00240.23 CDJ97836.1 - 1.5e-37 127.1 0.0 4e-18 64.9 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 CDJ97836.1 - 1.9e-15 56.4 0.0 2.5e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like zf-RING_UBOX PF13445.6 CDJ97836.1 - 6e-08 32.6 6.5 1.2e-07 31.6 6.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Rad60-SLD_2 PF13881.6 CDJ97836.1 - 4.3e-06 26.8 0.0 0.014 15.5 0.0 2.8 2 1 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like zf-C3HC4 PF00097.25 CDJ97836.1 - 1.7e-05 24.6 8.3 3.8e-05 23.5 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ubiquitin_2 PF14560.6 CDJ97836.1 - 5.2e-05 23.6 0.0 0.8 10.2 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin-like domain zf-C3HC4_3 PF13920.6 CDJ97836.1 - 7.9e-05 22.4 6.5 0.00016 21.5 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ97836.1 - 0.00011 22.0 7.9 0.00026 20.8 7.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ97836.1 - 0.00012 22.2 6.5 0.00025 21.1 6.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CDJ97836.1 - 0.00042 20.6 7.6 0.0012 19.1 7.6 1.8 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CDJ97836.1 - 0.0013 18.6 6.0 0.0027 17.5 6.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CDJ97836.1 - 0.0015 18.5 7.6 0.0031 17.4 7.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Ubiquitin_4 PF18036.1 CDJ97836.1 - 0.0061 16.6 0.3 1.2 9.3 0.1 3.3 2 1 0 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CDJ97836.1 - 0.065 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain zf-RING_11 PF17123.5 CDJ97836.1 - 0.98 9.2 8.1 3 7.7 8.1 1.9 1 0 0 1 1 1 0 RING-like zinc finger ubiquitin PF00240.23 CDJ97837.1 - 1.4e-17 63.2 0.0 2.9e-17 62.2 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CDJ97837.1 - 1.7e-08 34.2 0.0 2.4e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-C3HC4 PF00097.25 CDJ97837.1 - 3.4e-06 26.8 17.4 5.6e-06 26.1 17.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ97837.1 - 8.7e-06 25.7 15.1 1.6e-05 24.8 15.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDJ97837.1 - 2.2e-05 24.2 14.6 3.5e-05 23.6 14.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ97837.1 - 2.8e-05 24.3 16.1 4.5e-05 23.7 16.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CDJ97837.1 - 5e-05 23.2 15.0 8.4e-05 22.5 15.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDJ97837.1 - 0.0037 17.1 11.7 0.0081 16.0 11.7 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CDJ97837.1 - 0.016 15.1 18.7 0.051 13.4 18.7 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ97837.1 - 0.04 14.1 17.3 0.082 13.1 17.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ubiquitin_2 PF14560.6 CDJ97837.1 - 0.08 13.4 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain zf-RING_4 PF14570.6 CDJ97837.1 - 1.2 9.0 10.4 4 7.3 10.6 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 CDJ97837.1 - 2.2 8.6 11.7 4.4 7.7 11.7 1.5 1 1 0 1 1 1 0 RING-H2 zinc finger domain GTP_EFTU_D3 PF03143.17 CDJ97838.1 - 4.4e-11 43.1 0.0 8.7e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CDJ97838.1 - 0.0022 18.3 0.0 0.0048 17.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Pkinase PF00069.25 CDJ97839.1 - 1.3e-65 221.4 0.0 1.9e-65 220.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ97839.1 - 7.3e-49 166.4 0.0 1.1e-48 165.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 CDJ97839.1 - 6.2e-18 65.1 7.2 1.1e-16 61.0 7.2 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Kdo PF06293.14 CDJ97839.1 - 0.00011 21.7 0.1 0.00019 20.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDJ97839.1 - 0.00073 19.2 0.1 0.0014 18.3 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 CDJ97839.1 - 0.0034 16.2 0.0 0.0061 15.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDJ97839.1 - 0.011 15.1 0.0 0.067 12.5 0.0 2.1 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 CDJ97839.1 - 0.024 14.5 0.0 0.22 11.4 0.0 2.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family ShK PF01549.24 CDJ97840.1 - 5e-05 23.7 2.4 6.5e-05 23.4 2.4 1.2 1 0 0 1 1 1 1 ShK domain-like Misat_Tub_SegII PF10644.9 CDJ97840.1 - 0.18 12.1 0.0 0.2 12.0 0.0 1.1 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain PHO4 PF01384.20 CDJ97841.1 - 9.5e-92 307.6 15.8 1.3e-91 307.2 15.8 1.2 1 0 0 1 1 1 1 Phosphate transporter family SCF PF02404.15 CDJ97841.1 - 0.19 11.0 0.1 0.37 10.1 0.1 1.4 1 0 0 1 1 1 0 Stem cell factor ISG65-75 PF11727.8 CDJ97842.1 - 0.097 11.9 1.0 0.1 11.8 1.0 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF1180 PF06679.12 CDJ97844.1 - 0.078 13.4 0.5 0.083 13.3 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Herpes_capsid PF06112.11 CDJ97844.1 - 9.1 6.3 18.2 10 6.2 18.2 1.0 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DKCLD PF08068.12 CDJ97845.1 - 8e-32 109.1 0.0 8.1e-31 105.9 0.1 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 CDJ97845.1 - 4.8e-23 82.2 4.1 4.8e-21 75.7 0.7 3.6 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 CDJ97845.1 - 4e-19 68.3 1.1 8.6e-19 67.3 1.1 1.6 1 0 0 1 1 1 1 PUA domain TruB_C_2 PF16198.5 CDJ97845.1 - 2.6e-18 65.9 1.6 4.9e-18 65.0 1.6 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain UPF0113 PF03657.13 CDJ97845.1 - 0.0016 18.7 0.0 0.0041 17.3 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain PseudoU_synth_2 PF00849.22 CDJ97845.1 - 0.025 14.7 0.9 0.056 13.5 0.0 2.0 2 0 0 2 2 2 0 RNA pseudouridylate synthase DUF5611 PF18446.1 CDJ97845.1 - 0.14 13.0 2.3 1.1 10.2 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5611) Ras PF00071.22 CDJ97846.1 - 5.8e-50 169.0 0.0 6.8e-50 168.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ97846.1 - 5.9e-31 107.2 0.1 1.3e-30 106.0 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ97846.1 - 8.1e-11 41.7 0.0 1.1e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 CDJ97846.1 - 6.8e-05 23.2 0.1 0.00031 21.1 0.1 1.9 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 CDJ97846.1 - 0.00016 21.7 0.0 0.00031 20.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDJ97846.1 - 0.0018 17.7 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CDJ97846.1 - 0.0026 17.3 0.6 0.011 15.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 CDJ97846.1 - 0.0054 16.5 0.0 0.0094 15.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 CDJ97846.1 - 0.027 13.9 0.1 0.049 13.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Septin PF00735.18 CDJ97846.1 - 0.035 13.4 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 CDJ97846.1 - 0.038 13.5 0.1 0.065 12.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 CDJ97846.1 - 0.039 13.8 0.1 9 6.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase ArgoMid PF16487.5 CDJ97846.1 - 0.045 14.0 0.0 0.084 13.1 0.0 1.5 1 0 0 1 1 1 0 Mid domain of argonaute AAA_16 PF13191.6 CDJ97846.1 - 0.093 13.1 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 CDJ97846.1 - 0.093 12.9 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain GCD14_N PF14801.6 CDJ97846.1 - 0.097 12.5 0.5 9.4 6.2 0.1 2.3 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit N-term ATPase PF06745.13 CDJ97846.1 - 0.11 11.8 0.2 0.16 11.3 0.2 1.2 1 0 0 1 1 1 0 KaiC TsaE PF02367.17 CDJ97846.1 - 0.14 12.1 0.3 0.32 11.0 0.3 1.5 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE G-alpha PF00503.20 CDJ97846.1 - 0.15 11.2 3.6 2.3 7.3 0.2 2.8 2 1 1 3 3 3 0 G-protein alpha subunit ATP_bind_1 PF03029.17 CDJ97846.1 - 0.17 11.7 0.1 10 5.8 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Glyco_transf_64 PF09258.10 CDJ97847.1 - 1.2e-83 280.1 0.4 1.2e-83 280.1 0.4 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 CDJ97847.1 - 3.9e-20 72.3 0.3 2.3e-19 69.7 0.3 2.2 1 1 0 1 1 1 1 Exostosin family EzrA PF06160.12 CDJ97847.1 - 0.081 11.1 1.4 0.12 10.5 1.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Spectrin PF00435.21 CDJ97847.1 - 0.12 12.9 1.5 0.37 11.3 1.6 1.7 2 0 0 2 2 2 0 Spectrin repeat TMEM239 PF15841.5 CDJ97848.1 - 0.1 12.5 0.4 0.1 12.5 0.4 1.8 1 1 1 2 2 2 0 Transmembrane protein 239 family 2OG-FeII_Oxy_2 PF13532.6 CDJ97849.1 - 1.6e-37 129.6 0.0 2.2e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2633 PF11119.8 CDJ97849.1 - 0.087 12.7 0.7 0.18 11.8 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) Rad4 PF03835.15 CDJ97850.1 - 7e-26 90.7 2.7 7e-26 90.7 2.7 3.0 2 1 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 CDJ97850.1 - 3.1e-21 75.6 0.0 1.4e-20 73.5 0.0 2.1 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 CDJ97850.1 - 3.5e-17 62.0 0.5 9.6e-17 60.6 0.5 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 CDJ97850.1 - 3.4e-09 37.5 4.2 3.4e-09 37.5 4.2 5.0 4 2 0 4 4 4 1 Rad4 beta-hairpin domain 2 Arm-DNA-bind_4 PF14657.6 CDJ97850.1 - 0.46 10.3 9.6 0.38 10.6 6.6 2.4 2 0 0 2 2 2 0 Arm DNA-binding domain Rad4 PF03835.15 CDJ97851.1 - 2.8e-22 79.0 2.5 2.8e-22 79.0 2.5 5.2 6 1 0 6 6 6 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 CDJ97851.1 - 4e-20 72.0 0.0 9.3e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 CDJ97851.1 - 3.3e-15 55.6 0.1 1.1e-14 53.9 0.1 2.0 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 CDJ97851.1 - 3.5e-07 31.1 2.9 3.5e-07 31.1 2.9 6.7 6 2 0 6 6 6 1 Rad4 beta-hairpin domain 2 JAB PF01398.21 CDJ97852.1 - 8.8e-18 64.4 0.0 1.7e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 CDJ97852.1 - 3.7e-11 43.2 0.1 1.8e-10 41.0 0.0 1.9 2 0 0 2 2 2 1 USP8 dimerisation domain Prok-JAB PF14464.6 CDJ97852.1 - 4.8e-05 23.1 0.1 0.00014 21.6 0.1 1.8 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain IFRD PF05004.13 CDJ97854.1 - 5.7e-44 150.4 4.8 7.7e-44 150.0 4.8 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.12 CDJ97854.1 - 3.1e-16 59.7 1.6 3.1e-16 59.7 1.6 1.8 2 0 0 2 2 2 1 Interferon-related protein conserved region BID PF06393.11 CDJ97854.1 - 0.0073 15.9 0.2 0.015 14.8 0.2 1.5 1 0 0 1 1 1 1 BH3 interacting domain (BID) ATP_bind_3 PF01171.20 CDJ97855.1 - 1.4e-16 60.8 0.0 2.3e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 CDJ97855.1 - 8.7e-16 57.1 3.9 8.7e-16 57.1 3.9 2.4 2 0 0 2 2 2 1 Zinc-ribbon RecR PF02132.15 CDJ97855.1 - 0.033 13.7 0.5 0.033 13.7 0.5 2.7 3 0 0 3 3 3 0 RecR protein ThiI PF02568.14 CDJ97855.1 - 0.088 12.4 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) RRM_1 PF00076.22 CDJ97856.1 - 3.9e-25 87.5 0.0 3.2e-11 42.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.13 CDJ97856.1 - 6.6e-14 52.1 0.0 1.1e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 SPOC domain RRM_3 PF08777.11 CDJ97856.1 - 2.4e-09 37.2 0.1 0.0013 18.7 0.0 3.9 3 1 0 3 3 3 3 RNA binding motif RRM_7 PF16367.5 CDJ97856.1 - 8.2e-06 25.9 0.0 0.0023 18.0 0.0 2.8 2 1 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 CDJ97856.1 - 0.0015 18.5 0.2 0.14 12.2 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CDJ97856.1 - 0.033 14.0 0.0 1.9 8.4 0.0 2.7 2 0 0 2 2 2 0 Occluded RNA-recognition motif Ras PF00071.22 CDJ97857.1 - 6.5e-59 198.2 0.0 7.5e-59 197.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ97857.1 - 1.3e-31 109.3 0.0 1.9e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ97857.1 - 5.8e-11 42.2 0.0 6.5e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ97857.1 - 4.2e-07 30.1 0.0 5.9e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDJ97857.1 - 5.7e-05 22.6 0.0 7.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CDJ97857.1 - 0.00012 22.1 0.0 0.0042 17.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CDJ97857.1 - 0.0004 20.0 0.0 0.015 14.9 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.19 CDJ97857.1 - 0.0013 18.4 0.0 0.0073 15.9 0.0 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 CDJ97857.1 - 0.0015 18.9 0.2 0.011 16.2 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDJ97857.1 - 0.0051 17.1 0.0 0.01 16.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain Septin PF00735.18 CDJ97857.1 - 0.0061 15.9 0.1 0.014 14.6 0.0 1.6 2 0 0 2 2 2 1 Septin SRPRB PF09439.10 CDJ97857.1 - 0.022 14.2 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 CDJ97857.1 - 0.026 14.2 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDJ97857.1 - 0.03 13.8 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 CDJ97857.1 - 0.031 14.2 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 CDJ97857.1 - 0.047 13.4 0.1 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 CDJ97857.1 - 0.056 13.2 0.1 4.3 7.1 0.0 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DAP3 PF10236.9 CDJ97857.1 - 0.095 11.8 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.27 CDJ97857.1 - 0.1 13.1 0.2 0.18 12.3 0.2 1.8 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 CDJ97857.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.5 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 CDJ97857.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 CDJ97857.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein DUF2755 PF10954.8 CDJ97859.1 - 0.094 12.7 0.0 2.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2755) ATP-synt_ab PF00006.25 CDJ97860.1 - 2.8e-73 246.1 0.0 4.6e-73 245.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 CDJ97860.1 - 1.8e-47 160.8 1.7 3.2e-47 160.0 1.7 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 CDJ97860.1 - 2.5e-18 66.3 1.7 8.9e-18 64.6 1.7 2.0 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 CDJ97860.1 - 0.01 15.9 0.5 0.041 14.0 0.5 2.1 1 1 0 1 1 1 0 HAS barrel domain DUF4142 PF13628.6 CDJ97860.1 - 0.092 13.0 1.7 0.21 11.8 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) MCRS_N PF13325.6 CDJ97861.1 - 2.6e-36 125.5 1.6 7.2e-36 124.1 0.0 2.1 2 0 0 2 2 2 1 N-terminal region of micro-spherule protein FHA PF00498.26 CDJ97861.1 - 4.4e-08 33.4 0.0 7.5e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 CDJ97861.1 - 0.0081 16.4 0.0 0.021 15.1 0.0 1.7 1 1 0 1 1 1 1 FHA domain RGS_DHEX PF18148.1 CDJ97862.1 - 7.6e-40 135.1 1.6 1.9e-39 133.8 1.6 1.7 1 0 0 1 1 1 1 Regulator of G-protein signalling DHEX domain RGS PF00615.19 CDJ97862.1 - 9.8e-33 112.9 2.8 1.2e-31 109.4 0.1 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain G-gamma PF00631.22 CDJ97862.1 - 1.4e-09 37.8 0.0 3.7e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 GGL domain DEP PF00610.21 CDJ97862.1 - 1e-08 35.1 0.0 3.8e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Methyltrans_RNA PF04452.14 CDJ97862.1 - 0.12 11.7 0.2 0.3 10.4 0.0 1.7 2 0 0 2 2 2 0 RNA methyltransferase Histone_H2A_C PF16211.5 CDJ97863.1 - 1.2e-20 73.0 1.7 2.3e-20 72.0 1.7 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CDJ97863.1 - 1.5e-15 57.7 0.0 1.8e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CDJ97863.1 - 5.7e-06 26.5 0.0 7.4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDJ97864.1 - 1.6e-24 86.7 1.6 2e-24 86.4 1.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CDJ97864.1 - 5.2e-07 29.9 0.0 1.4e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CDJ97864.1 - 0.00051 20.5 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 CDJ97864.1 - 0.00087 19.4 0.8 0.0011 19.0 0.8 1.2 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 CDJ97864.1 - 0.037 13.7 1.9 2.9 7.5 0.0 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain DUF1931 PF09123.11 CDJ97864.1 - 0.071 13.2 0.0 0.2 11.8 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1931) CENP-T_C PF15511.6 CDJ97865.1 - 3.6e-08 33.5 0.1 4.4e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 CDJ97865.1 - 1.8e-05 25.0 0.1 2.4e-05 24.6 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 CDJ97865.1 - 6.9e-05 22.9 0.1 9.7e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CDJ97865.1 - 7e-05 23.0 0.1 0.00012 22.3 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDJ97865.1 - 0.00023 21.5 0.2 0.00026 21.3 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 CDJ97865.1 - 0.0036 17.3 0.0 0.0055 16.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 CDJ97865.1 - 0.009 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit RRM_1 PF00076.22 CDJ97866.1 - 7.2e-27 93.0 0.0 8.9e-11 41.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CDJ97866.1 - 0.021 14.9 0.1 8.2 6.6 0.0 2.4 2 0 0 2 2 2 0 Limkain b1 RhoGAP PF00620.27 CDJ97867.1 - 5.5e-06 26.3 0.3 1.2e-05 25.2 0.3 1.5 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 CDJ97867.1 - 6e-06 25.9 0.0 7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BSD PF03909.17 CDJ97868.1 - 1.6e-14 53.7 0.6 4e-14 52.4 0.0 2.0 2 0 0 2 2 2 1 BSD domain Headcase PF16002.5 CDJ97869.1 - 2.1e-48 164.4 5.6 3.7e-48 163.6 5.6 1.4 1 1 0 1 1 1 1 Headcase protein Acyltransferase PF01553.21 CDJ97870.1 - 5.2e-16 58.5 0.0 8.4e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CDJ97870.1 - 1.7e-12 47.2 0.0 4.4e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus zf-MYND PF01753.18 CDJ97871.1 - 2.6e-10 40.2 9.9 2.6e-10 40.2 9.9 2.5 2 1 0 2 2 2 1 MYND finger SET PF00856.28 CDJ97871.1 - 1.3 9.4 3.2 5.5 7.3 3.2 2.2 1 1 0 1 1 1 0 SET domain RA PF00788.23 CDJ97872.1 - 3.5e-34 117.3 0.0 2.5e-20 72.9 0.0 2.6 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain FHA PF00498.26 CDJ97872.1 - 3.1e-06 27.4 0.0 5.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CDJ97872.1 - 0.0063 16.8 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain CTP_transf_like PF01467.26 CDJ97873.1 - 6.1e-09 36.2 0.1 1.5e-08 35.0 0.1 1.6 1 0 0 1 1 1 1 Cytidylyltransferase-like Oxidored_FMN PF00724.20 CDJ97874.1 - 9.3e-40 136.9 0.0 1.4e-39 136.3 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 CDJ97874.1 - 0.006 16.0 0.0 32 3.9 0.0 2.1 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Oxidored_FMN PF00724.20 CDJ97875.1 - 1.1e-37 130.1 0.0 1.6e-37 129.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1697 PF08002.11 CDJ97875.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) Oxidored_FMN PF00724.20 CDJ97876.1 - 3.3e-34 118.7 0.0 4.3e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family LPP20 PF02169.16 CDJ97877.1 - 0.097 13.0 0.9 0.13 12.7 0.9 1.2 1 0 0 1 1 1 0 LPP20 lipoprotein Metallophos PF00149.28 CDJ97878.1 - 1.1e-30 107.7 0.0 1.7e-30 107.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ground-like PF04155.18 CDJ97879.1 - 1.4e-24 86.5 2.3 2e-24 86.1 2.3 1.2 1 0 0 1 1 1 1 Ground-like domain I_LWEQ PF01608.17 CDJ97880.1 - 0.047 13.9 0.2 0.074 13.3 0.2 1.3 1 0 0 1 1 1 0 I/LWEQ domain LRR_8 PF13855.6 CDJ97881.1 - 9.9e-13 47.7 2.4 2.4e-09 36.8 1.4 2.6 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CDJ97881.1 - 2.9e-07 30.7 1.3 2.9e-07 30.7 1.3 2.9 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CDJ97881.1 - 4.4e-05 23.5 0.0 6.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) Myc_N PF01056.18 CDJ97881.1 - 0.0063 16.5 2.1 0.0075 16.2 2.1 1.1 1 0 0 1 1 1 1 Myc amino-terminal region LRR_1 PF00560.33 CDJ97881.1 - 0.036 14.6 7.1 10 7.1 0.9 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 CDJ97881.1 - 0.087 12.9 1.9 17 5.8 0.1 2.8 2 0 0 2 2 2 0 Leucine Rich repeat MFS_1 PF07690.16 CDJ97883.1 - 2e-41 142.1 26.9 1e-38 133.2 19.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.9 CDJ97883.1 - 0.08 13.2 1.6 12 6.2 0.3 2.9 2 1 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Nuf2 PF03800.14 CDJ97885.1 - 3.8e-24 85.4 1.1 1e-23 84.0 1.1 1.8 1 0 0 1 1 1 1 Nuf2 family FH2 PF02181.23 CDJ97885.1 - 0.0039 16.4 6.3 0.0039 16.4 6.3 2.9 2 1 0 3 3 3 1 Formin Homology 2 Domain DUF3135 PF11333.8 CDJ97885.1 - 0.35 11.1 5.4 0.39 11.0 1.5 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3135) DUF2680 PF10925.8 CDJ97885.1 - 0.41 10.7 5.3 2.1 8.4 0.7 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2680) P-mevalo_kinase PF04275.14 CDJ97885.1 - 1.2 9.1 10.7 1.2 9.1 0.5 3.1 2 1 1 3 3 3 0 Phosphomevalonate kinase T4SS PF07996.11 CDJ97885.1 - 6.1 7.2 20.8 1.5e+02 2.7 20.9 2.9 1 1 0 1 1 1 0 Type IV secretion system proteins Glycos_transf_2 PF00535.26 CDJ97886.1 - 5.9e-31 107.6 0.0 9.1e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CDJ97886.1 - 1.2e-15 57.9 5.5 2.7e-15 56.8 5.0 1.8 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 CDJ97886.1 - 2.2e-07 30.5 0.0 6e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CDJ97886.1 - 9.3e-05 22.0 0.0 0.00021 20.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CDJ97886.1 - 0.0054 16.7 0.0 0.016 15.1 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase family group 2 AMP-binding PF00501.28 CDJ97887.1 - 2e-82 277.1 0.0 2.4e-82 276.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ97887.1 - 3e-16 60.2 0.3 8.1e-16 58.8 0.1 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain RRM_1 PF00076.22 CDJ97888.1 - 0.025 14.4 0.0 0.051 13.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 CDJ97889.1 - 3.2e-53 180.8 0.0 4.1e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ97889.1 - 1.4e-26 93.4 0.0 1.9e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ97889.1 - 0.022 13.7 0.2 0.043 12.8 0.2 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 CDJ97889.1 - 0.076 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Y_phosphatase PF00102.27 CDJ97891.1 - 7.1e-12 45.4 0.1 9.1e-12 45.0 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase BBS2_Mid PF14783.6 CDJ97892.1 - 0.004 17.2 0.0 0.013 15.6 0.0 1.8 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region BBS2_C PF14782.6 CDJ97892.1 - 0.015 14.1 0.2 0.024 13.4 0.2 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Pox_A_type_inc PF04508.12 CDJ97892.1 - 0.12 12.3 1.2 0.29 11.0 1.2 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Peptidase_S78_2 PF14550.6 CDJ97893.1 - 0.061 13.4 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Putative phage serine protease XkdF zf-Nse PF11789.8 CDJ97893.1 - 0.1 12.5 1.2 0.24 11.2 0.3 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit HLH PF00010.26 CDJ97894.1 - 4.2e-11 42.6 4.2 5.5e-11 42.3 3.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain p450 PF00067.22 CDJ97895.1 - 7.7e-95 318.3 0.0 9.1e-95 318.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ELFV_dehydrog_N PF02812.18 CDJ97895.1 - 0.12 12.3 0.0 0.89 9.4 0.0 2.1 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain CG-1 PF03859.16 CDJ97896.1 - 1.1e-36 125.2 1.3 1.9e-36 124.4 1.3 1.4 1 0 0 1 1 1 1 CG-1 domain TIG PF01833.24 CDJ97896.1 - 2.6e-07 30.6 0.6 8e-07 29.1 0.6 1.8 1 0 0 1 1 1 1 IPT/TIG domain Ank_5 PF13857.6 CDJ97896.1 - 9.5e-07 29.0 1.1 2e-05 24.8 0.0 3.2 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ97896.1 - 6.7e-06 26.6 0.0 2.2e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ97896.1 - 1.8e-05 25.2 0.2 8.2e-05 23.1 0.1 2.3 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ97896.1 - 0.0016 18.7 0.1 0.14 12.8 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 CDJ97896.1 - 0.0018 18.6 0.5 0.14 12.7 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat BCL_N PF04714.13 CDJ97897.1 - 0.0072 16.4 0.9 0.013 15.5 0.9 1.4 1 0 0 1 1 1 1 BCL7, N-terminal conserver region Amidohydro_3 PF07969.11 CDJ97898.1 - 8.8e-17 61.7 0.2 1e-16 61.5 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 CDJ97898.1 - 4.4e-16 59.1 0.1 6.8e-16 58.5 0.1 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 CDJ97899.1 - 0.0011 18.3 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CDJ97899.1 - 0.01 15.3 0.1 0.014 14.9 0.1 1.4 1 0 0 1 1 1 0 Amidohydrolase family Actino_peptide PF14408.6 CDJ97899.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Ribosomally synthesised peptide in actinomycetes STT3 PF02516.14 CDJ97900.1 - 2.2e-162 541.4 40.6 8.9e-159 529.5 36.3 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit UXS1_N PF11803.8 CDJ97900.1 - 0.21 12.0 3.8 1.5 9.3 0.0 2.9 3 0 0 3 3 3 0 UDP-glucuronate decarboxylase N-terminal DUF4231 PF14015.6 CDJ97900.1 - 0.3 11.6 6.1 18 5.8 0.3 4.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) OppC_N PF12911.7 CDJ97900.1 - 2.5 8.2 5.6 20 5.3 0.0 3.9 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Peptidase_M56 PF05569.11 CDJ97900.1 - 3.8 6.6 7.0 1.1 8.4 0.1 2.8 2 1 1 3 3 3 0 BlaR1 peptidase M56 BCAS2 PF05700.11 CDJ97901.1 - 6.1e-53 179.6 10.7 6.1e-53 179.6 10.7 1.6 2 0 0 2 2 2 1 Breast carcinoma amplified sequence 2 (BCAS2) XPG_I PF00867.18 CDJ97901.1 - 4.8e-19 68.5 0.0 1.9e-18 66.6 0.0 2.1 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CDJ97901.1 - 1e-13 51.6 0.0 2.5e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain IRS PF02174.17 CDJ97901.1 - 0.041 13.8 0.6 0.65 9.9 0.0 2.4 2 0 0 2 2 2 0 PTB domain (IRS-1 type) Hormone_recep PF00104.30 CDJ97903.1 - 4e-07 29.8 0.0 5.4e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor SMC_N PF02463.19 CDJ97907.1 - 2.2e-69 233.3 23.1 2.9e-68 229.6 23.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CDJ97907.1 - 3.4e-22 78.9 0.0 1.2e-21 77.2 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CDJ97907.1 - 6.9e-14 52.4 4.7 2.4e-06 27.6 0.1 3.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CDJ97907.1 - 7.3e-07 29.2 4.2 7.3e-07 29.2 4.2 4.5 2 1 1 4 4 2 1 AAA ATPase domain AAA_29 PF13555.6 CDJ97907.1 - 4.3e-05 23.2 0.0 8.3e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_24 PF13479.6 CDJ97907.1 - 0.00048 19.9 3.9 0.15 11.7 0.8 4.0 3 0 0 3 3 3 1 AAA domain DUF4201 PF13870.6 CDJ97907.1 - 0.0055 16.5 9.5 0.0055 16.5 9.5 7.2 4 2 1 6 6 6 3 Domain of unknown function (DUF4201) AAA_22 PF13401.6 CDJ97907.1 - 0.057 13.7 5.8 2.2 8.5 0.0 4.8 5 0 0 5 5 5 0 AAA domain ABC_tran PF00005.27 CDJ97907.1 - 0.086 13.4 0.0 0.086 13.4 0.0 6.0 5 2 0 5 5 4 0 ABC transporter DUF5631 PF18645.1 CDJ97907.1 - 0.36 11.2 2.8 1.5 9.2 0.1 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5631) MscS_porin PF12795.7 CDJ97907.1 - 1.6 8.2 68.2 0.043 13.4 1.2 5.8 6 1 0 6 6 6 0 Mechanosensitive ion channel porin domain Hormone_recep PF00104.30 CDJ97908.1 - 4.7e-17 62.2 0.1 8.2e-17 61.5 0.1 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 CDJ97908.1 - 0.013 15.9 4.0 0.03 14.8 4.0 1.7 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) HTH_Tnp_Tc5 PF03221.16 CDJ97909.1 - 2.8e-11 43.3 0.0 6.5e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain UPF0122 PF04297.14 CDJ97909.1 - 0.091 13.0 0.1 0.31 11.3 0.0 1.9 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like Tom37 PF10568.9 CDJ97910.1 - 3.1e-28 98.6 0.0 6.1e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 CDJ97910.1 - 4.8e-24 85.0 0.0 1.5e-23 83.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 CDJ97910.1 - 2.3e-19 68.9 0.2 5.6e-19 67.7 0.2 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDJ97910.1 - 2.9e-11 43.2 0.0 8.3e-11 41.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDJ97910.1 - 0.00045 20.4 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDJ97910.1 - 0.0033 17.6 0.1 0.013 15.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Arb2 PF09757.9 CDJ97910.1 - 0.017 14.2 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Arb2 domain DEAD PF00270.29 CDJ97911.1 - 2e-32 112.4 0.0 3.6e-32 111.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ97911.1 - 2e-24 86.1 0.1 1.3e-23 83.5 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ97911.1 - 3.4e-09 36.9 0.0 8e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CDJ97911.1 - 0.00078 19.7 0.5 0.032 14.5 0.4 2.7 1 1 0 1 1 1 1 AAA domain TPR_12 PF13424.6 CDJ97911.1 - 0.11 12.8 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1168 PF06658.12 CDJ97912.1 - 9.5e-38 129.1 20.7 1.5e-37 128.4 20.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF4746 PF15928.5 CDJ97912.1 - 0.21 11.0 12.3 0.22 10.9 12.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CENP-Q PF13094.6 CDJ97912.1 - 0.51 10.5 16.1 0.86 9.8 16.1 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit CNDH2_C PF16858.5 CDJ97912.1 - 1.1 9.0 19.4 0.41 10.5 17.1 1.4 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term V_ATPase_I PF01496.19 CDJ97912.1 - 1.4 6.8 8.7 1.7 6.4 8.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM60A PF15396.6 CDJ97912.1 - 1.5 8.8 14.6 2 8.4 14.6 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF1192 PF06698.11 CDJ97912.1 - 1.7 8.7 13.8 0.37 10.9 9.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) GCD14 PF08704.10 CDJ97912.1 - 3.7 7.2 7.6 5 6.7 7.6 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Eapp_C PF10238.9 CDJ97912.1 - 3.7 7.6 12.2 6 6.9 12.2 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein VIR_N PF15912.5 CDJ97912.1 - 5.6 6.5 15.0 8.5 5.9 15.0 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal FancD2 PF14631.6 CDJ97912.1 - 5.6 4.2 11.8 6 4.1 11.8 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease MscS_TM PF12794.7 CDJ97912.1 - 8.7 5.1 9.3 13 4.5 9.3 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Abhydrolase_1 PF00561.20 CDJ97913.1 - 3.1e-13 50.0 0.0 4.4e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ97913.1 - 2.2e-08 33.7 0.0 3.5e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDJ97913.1 - 1.1e-06 29.4 0.6 2.2e-06 28.4 0.6 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CDJ97913.1 - 0.018 14.5 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family UPF0227 PF05728.12 CDJ97913.1 - 0.041 13.8 0.1 0.094 12.6 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Asp2 PF16929.5 CDJ97913.1 - 0.092 11.7 0.0 0.2 10.6 0.0 1.4 2 0 0 2 2 2 0 Accessory Sec system GspB-transporter DUF3839 PF12943.7 CDJ97914.1 - 0.032 13.7 0.6 0.041 13.3 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3839) Lipase_2 PF01674.18 CDJ97915.1 - 2.4e-75 252.8 0.0 2.8e-75 252.6 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 2) Abhydrolase_6 PF12697.7 CDJ97915.1 - 0.00067 20.3 0.1 0.00077 20.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 CDJ97915.1 - 0.009 15.8 0.6 0.061 13.0 0.6 2.0 1 1 0 1 1 1 1 PGAP1-like protein DUF900 PF05990.12 CDJ97915.1 - 0.017 14.6 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.15 CDJ97915.1 - 0.1 11.7 0.0 0.25 10.4 0.0 1.5 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase RMMBL PF07521.12 CDJ97915.1 - 0.18 11.7 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain CUB PF00431.20 CDJ97916.1 - 5.4e-16 58.9 0.1 1.1e-15 57.9 0.1 1.6 1 0 0 1 1 1 1 CUB domain DHquinase_I PF01487.15 CDJ97916.1 - 4.8e-05 23.7 0.0 7.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase PRK PF00485.18 CDJ97917.1 - 3.6e-43 147.6 0.0 4.3e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 CDJ97917.1 - 9.8e-07 29.4 0.0 1.5e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain CoaE PF01121.20 CDJ97917.1 - 8.6e-05 22.3 1.1 0.003 17.3 1.1 2.2 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_19 PF13245.6 CDJ97917.1 - 0.029 14.7 0.0 0.045 14.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CDJ97917.1 - 0.036 14.5 0.0 0.052 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 CDJ97917.1 - 0.042 13.1 0.0 0.08 12.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 CDJ97917.1 - 0.062 13.7 0.3 5.7 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 CDJ97917.1 - 0.066 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF2075 PF09848.9 CDJ97917.1 - 0.093 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PRK PF00485.18 CDJ97918.1 - 8.2e-47 159.5 0.0 9.7e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 CDJ97918.1 - 0.0001 22.8 0.0 0.00017 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain CoaE PF01121.20 CDJ97918.1 - 0.0015 18.2 0.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 2 Dephospho-CoA kinase DUF4852 PF16144.5 CDJ97918.1 - 0.0077 16.3 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4852) AAA_19 PF13245.6 CDJ97918.1 - 0.017 15.5 0.0 0.023 15.0 0.0 1.2 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CDJ97918.1 - 0.062 12.5 0.0 0.11 11.6 0.0 1.5 1 1 1 2 2 2 0 NB-ARC domain Lipase_3 PF01764.25 CDJ97920.1 - 7e-31 107.0 0.0 1e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 CDJ97920.1 - 0.02 14.4 0.1 0.4 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 CDJ97920.1 - 0.021 15.5 0.0 0.027 15.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.16 CDJ97921.1 - 2.8e-31 108.7 21.5 2.2e-20 72.9 11.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ97921.1 - 3.9e-27 95.2 19.1 2.2e-26 92.7 19.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4443 PF14544.6 CDJ97921.1 - 0.084 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4443) MRG PF05712.13 CDJ97923.1 - 9.9e-34 116.4 0.0 1.4e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 CDJ97923.1 - 5.3e-08 32.6 1.1 5.3e-08 32.6 1.1 2.0 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain DUF1918 PF08940.11 CDJ97923.1 - 0.033 13.8 0.2 0.067 12.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) TF_AP-2 PF03299.14 CDJ97924.1 - 6.7e-39 133.9 0.0 1e-38 133.3 0.0 1.1 1 0 0 1 1 1 1 Transcription factor AP-2 HeH PF12949.7 CDJ97924.1 - 0.16 11.7 0.1 0.37 10.5 0.1 1.6 1 0 0 1 1 1 0 HeH/LEM domain DUF4236 PF14020.6 CDJ97924.1 - 0.21 12.2 0.0 0.21 12.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4236) CHDNT PF08073.12 CDJ97925.1 - 0.06 13.3 0.3 0.1 12.6 0.3 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain FIVAR PF07554.13 CDJ97925.1 - 0.096 13.5 0.2 0.16 12.7 0.2 1.4 1 0 0 1 1 1 0 FIVAR domain Guanylate_cyc PF00211.20 CDJ97926.1 - 3e-41 141.1 0.0 3.3e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain THAP PF05485.12 CDJ97927.1 - 7.1e-11 42.9 0.0 1e-10 42.4 0.0 1.4 1 0 0 1 1 1 1 THAP domain PID PF00640.23 CDJ97928.1 - 5.7e-38 130.1 0.6 5.7e-27 94.5 0.0 2.9 2 1 0 2 2 2 2 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 CDJ97928.1 - 9.5e-05 22.6 0.0 0.00059 20.0 0.0 2.3 2 1 0 2 2 2 1 Phosphotyrosine-binding domain rve PF00665.26 CDJ97928.1 - 0.027 14.7 0.2 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain LRR_4 PF12799.7 CDJ97929.1 - 1e-35 121.1 40.3 5.3e-10 39.4 2.4 6.5 5 2 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ97929.1 - 7.5e-27 92.9 60.1 1.5e-08 34.3 6.7 5.9 2 2 4 7 7 7 7 Leucine rich repeat LRR_9 PF14580.6 CDJ97929.1 - 8.3e-22 77.5 25.7 2.4e-07 30.4 3.3 4.5 1 1 3 4 4 4 4 Leucine-rich repeat LRR_3 PF07725.12 CDJ97929.1 - 0.011 15.5 9.0 3.6 7.6 0.1 5.6 6 0 0 6 6 6 0 Leucine Rich Repeat Ribosomal_L50 PF10501.9 CDJ97929.1 - 0.027 14.6 1.8 0.62 10.2 0.5 2.9 2 1 1 3 3 3 0 Ribosomal subunit 39S IGR PF09597.10 CDJ97929.1 - 0.06 13.5 3.4 15 5.8 0.1 4.6 4 1 2 6 6 6 0 IGR protein motif LRR_5 PF13306.6 CDJ97929.1 - 0.065 13.2 0.6 3.2 7.7 0.1 2.7 1 1 2 3 3 3 0 BspA type Leucine rich repeat region (6 copies) UB2H PF14814.6 CDJ97929.1 - 0.074 13.1 4.0 69 3.6 0.0 5.0 1 1 5 7 7 7 0 Bifunctional transglycosylase second domain LRR_1 PF00560.33 CDJ97929.1 - 0.15 12.7 25.9 6.3 7.8 0.1 8.4 7 1 1 8 8 8 0 Leucine Rich Repeat TRPM_tetra PF16519.5 CDJ97929.1 - 0.25 11.5 8.1 14 5.9 0.4 4.4 3 1 1 4 4 4 0 Tetramerisation domain of TRPM LRR_6 PF13516.6 CDJ97929.1 - 1.5 9.1 37.9 1.6 9.0 0.1 9.1 11 0 0 11 11 11 0 Leucine Rich repeat Arm_3 PF16186.5 CDJ97929.1 - 2.1 7.9 8.1 39 3.9 0.0 4.8 4 1 0 5 5 5 0 Atypical Arm repeat OST3_OST6 PF04756.13 CDJ97930.1 - 2.1e-102 342.4 1.3 2.8e-102 342.0 1.3 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF4131 PF13567.6 CDJ97930.1 - 0.0026 17.4 3.5 0.01 15.5 0.2 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4131) DUF4448 PF14610.6 CDJ97930.1 - 0.088 12.6 0.2 8.1 6.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) Yip1 PF04893.17 CDJ97930.1 - 0.71 9.6 12.6 51 3.5 10.5 3.2 2 1 0 2 2 2 0 Yip1 domain DUF3382 PF11862.8 CDJ97930.1 - 3.4 8.0 10.8 0.66 10.3 2.5 2.9 2 1 2 4 4 4 0 Domain of unknown function (DUF3382) FtsX PF02687.21 CDJ97930.1 - 5.7 7.5 10.0 3.9e+02 1.6 9.4 3.2 2 1 1 3 3 3 0 FtsX-like permease family zf-C2H2_jaz PF12171.8 CDJ97931.1 - 4.4e-07 30.0 0.7 8.3e-07 29.1 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDJ97931.1 - 2.1e-05 24.8 0.7 3.8e-05 23.9 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 CDJ97931.1 - 0.0001 22.0 1.6 0.0001 22.0 1.6 1.7 2 0 0 2 2 2 1 U1 zinc finger Motilin_assoc PF04643.12 CDJ97931.1 - 0.003 17.4 0.7 0.0082 16.0 0.7 1.7 1 0 0 1 1 1 1 Motilin/ghrelin-associated peptide SNRNP27 PF08648.12 CDJ97931.1 - 0.0064 16.5 0.3 0.0064 16.5 0.3 2.2 3 0 0 3 3 3 1 U4/U6.U5 small nuclear ribonucleoproteins ATP-synt_F6 PF05511.11 CDJ97931.1 - 0.16 12.4 0.3 0.16 12.4 0.3 2.6 2 2 1 3 3 3 0 Mitochondrial ATP synthase coupling factor 6 zf-C2H2 PF00096.26 CDJ97931.1 - 0.18 12.4 0.6 0.39 11.3 0.6 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type BTB PF00651.31 CDJ97932.1 - 5.9e-09 36.1 0.0 1.3e-08 35.0 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain 7TM_GPCR_Srw PF10324.9 CDJ97933.1 - 1e-41 143.3 26.6 1.4e-41 142.9 26.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 CDJ97933.1 - 0.0079 15.5 20.5 0.0065 15.8 19.0 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) HA2 PF04408.23 CDJ97934.1 - 6.1e-19 68.3 1.5 1.3e-18 67.2 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDJ97934.1 - 2.7e-14 53.3 0.0 7.5e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDJ97934.1 - 9.8e-12 45.2 0.0 1.5e-10 41.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ97934.1 - 1.6e-09 37.8 0.0 3.3e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDJ97934.1 - 0.00018 21.8 0.0 0.00084 19.6 0.0 2.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CDJ97934.1 - 0.0066 15.8 0.2 0.026 13.9 0.1 2.0 2 0 0 2 2 2 1 KaiC AAA_30 PF13604.6 CDJ97934.1 - 0.024 14.4 0.0 0.077 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF4852 PF16144.5 CDJ97934.1 - 0.093 12.9 1.1 0.2 11.8 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4852) AAA_23 PF13476.6 CDJ97934.1 - 0.12 12.9 0.1 0.12 12.9 0.1 2.7 3 0 0 3 3 3 0 AAA domain KinB_sensor PF16767.5 CDJ97935.1 - 0.023 15.2 0.1 0.098 13.1 0.1 2.1 2 0 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB HTH_22 PF13309.6 CDJ97935.1 - 0.15 12.2 0.2 7.4 6.7 0.0 3.5 5 0 0 5 5 5 0 HTH domain Comm PF15957.5 CDJ97938.1 - 5.9e-05 23.4 0.2 7.4e-05 23.1 0.2 1.1 1 0 0 1 1 1 1 Commissureless FAM163 PF15069.6 CDJ97938.1 - 0.00036 21.0 0.6 0.00044 20.7 0.6 1.1 1 0 0 1 1 1 1 FAM163 family EphA2_TM PF14575.6 CDJ97938.1 - 0.00067 20.5 0.1 0.00084 20.2 0.1 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 CDJ97938.1 - 0.0061 16.8 0.1 0.0065 16.7 0.1 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator CCER1 PF15482.6 CDJ97938.1 - 0.0089 16.0 0.2 0.0092 15.9 0.2 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing glutamate-rich protein family 1 Protocadherin PF08374.11 CDJ97938.1 - 0.011 15.7 0.0 0.012 15.6 0.0 1.0 1 0 0 1 1 1 0 Protocadherin Prominin PF05478.11 CDJ97938.1 - 0.012 13.6 2.7 0.013 13.5 2.7 1.1 1 0 0 1 1 1 0 Prominin Orthoreo_P10 PF07204.11 CDJ97938.1 - 0.025 14.5 0.3 0.031 14.2 0.3 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 7tm_1 PF00001.21 CDJ97938.1 - 0.029 13.7 0.1 0.03 13.6 0.1 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Myc_target_1 PF15179.6 CDJ97938.1 - 0.051 13.5 0.1 0.062 13.2 0.1 1.1 1 0 0 1 1 1 0 Myc target protein 1 Herpes_glycop PF01528.16 CDJ97938.1 - 0.064 12.1 0.5 0.076 11.9 0.5 1.0 1 0 0 1 1 1 0 Herpesvirus glycoprotein M LST1 PF05083.13 CDJ97938.1 - 0.075 13.3 0.6 0.1 12.9 0.6 1.4 1 0 0 1 1 1 0 LST-1 protein MLANA PF14991.6 CDJ97938.1 - 0.086 13.1 0.3 0.1 12.9 0.3 1.1 1 0 0 1 1 1 0 Protein melan-A LapA_dom PF06305.11 CDJ97938.1 - 0.35 10.7 3.5 0.8 9.6 3.5 1.7 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Glycophorin_A PF01102.18 CDJ97938.1 - 8.5 6.7 6.1 9.5 6.5 4.8 1.7 1 1 1 2 2 2 0 Glycophorin A Collagen PF01391.18 CDJ97939.1 - 3.1e-19 68.5 87.6 6.4e-11 41.8 31.9 6.0 4 1 1 5 5 5 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ97939.1 - 0.0045 17.0 1.5 0.0066 16.5 1.5 1.3 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain WD40 PF00400.32 CDJ97940.1 - 3.3e-05 24.5 0.9 0.048 14.6 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat CDC45 PF02724.14 CDJ97940.1 - 0.21 9.9 10.3 0.3 9.3 10.3 1.3 1 0 0 1 1 1 0 CDC45-like protein TPR_14 PF13428.6 CDJ97941.1 - 0.0016 19.1 2.1 44 5.3 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ97941.1 - 0.034 14.5 0.2 6.2 7.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ97941.1 - 0.093 12.8 3.9 1.7 8.8 0.2 3.8 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 CDJ97941.1 - 0.095 13.2 0.5 80 3.9 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ97941.1 - 0.51 10.7 2.7 24 5.5 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ97941.1 - 0.7 9.8 7.4 84 3.2 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TRM PF02005.16 CDJ97942.1 - 2.3e-141 471.3 0.0 3e-141 471.0 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 CDJ97942.1 - 0.00011 22.0 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_15 PF09445.10 CDJ97942.1 - 0.029 13.9 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 CDJ97942.1 - 0.039 13.6 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 CDJ97942.1 - 0.043 14.5 0.0 0.27 12.0 0.1 2.3 2 0 0 2 2 2 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 CDJ97942.1 - 0.05 12.6 0.0 0.086 11.8 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase PrmA PF06325.13 CDJ97942.1 - 0.06 12.7 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 CDJ97942.1 - 0.16 11.9 0.0 0.46 10.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PAP1 PF08601.10 CDJ97943.1 - 0.82 9.3 5.5 1.2 8.8 5.5 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 MBOAT PF03062.19 CDJ97945.1 - 4.4e-09 36.2 18.9 4.4e-09 36.2 18.9 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF1864 PF08933.11 CDJ97945.1 - 0.057 12.2 0.1 0.084 11.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) Ribosomal_S13 PF00416.22 CDJ97946.1 - 8e-54 181.4 0.6 9.4e-54 181.2 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 PP28 PF10252.9 CDJ97946.1 - 0.04 14.4 0.6 0.07 13.6 0.6 1.4 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 SecY PF00344.20 CDJ97947.1 - 2.1e-76 257.1 10.7 2.7e-76 256.8 10.7 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CDJ97947.1 - 4e-18 65.0 1.6 8.1e-18 64.0 0.1 2.4 2 0 0 2 2 2 1 Plug domain of Sec61p DUF2975 PF11188.8 CDJ97947.1 - 6.2 6.7 10.1 0.63 9.9 2.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) 7tm_1 PF00001.21 CDJ97948.1 - 2.5e-34 118.8 8.7 3.2e-34 118.4 8.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 CDJ97948.1 - 2.6e-06 27.4 4.1 6.4e-05 22.8 0.3 2.1 2 0 0 2 2 2 2 Olfactory receptor GT87 PF09594.10 CDJ97948.1 - 0.00018 21.3 0.8 0.00039 20.2 0.8 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 87 7TM_GPCR_Srx PF10328.9 CDJ97948.1 - 0.0098 15.5 0.9 0.0098 15.5 0.9 2.7 3 1 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx Cation_ATPase_C PF00689.21 CDJ97948.1 - 2.4 7.8 7.6 1.5 8.5 4.7 2.2 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus 7TM_GPCR_Srsx PF10320.9 CDJ97948.1 - 7 5.9 11.1 0.52 9.7 0.1 2.5 3 0 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srsx Syja_N PF02383.18 CDJ97953.1 - 1.3e-57 195.5 0.0 2e-57 194.9 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain DUF1866 PF08952.11 CDJ97953.1 - 1.1e-15 57.8 0.0 2e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1866) Exo_endo_phos PF03372.23 CDJ97953.1 - 5.6e-09 35.9 1.7 1.6e-08 34.3 0.3 2.3 3 0 0 3 3 3 1 Endonuclease/Exonuclease/phosphatase family Beta-Casp PF10996.8 CDJ97954.1 - 9.7e-32 109.5 0.0 2e-31 108.6 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain CPSF73-100_C PF11718.8 CDJ97954.1 - 1.8e-28 99.6 0.0 1.2e-27 96.9 0.0 2.0 1 1 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B_6 PF16661.5 CDJ97954.1 - 2.7e-19 69.4 0.0 4.7e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 CDJ97954.1 - 1.4e-17 64.4 0.2 4.1e-17 62.8 0.5 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 CDJ97954.1 - 4.2e-16 58.6 0.1 8.3e-16 57.7 0.1 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 CDJ97954.1 - 4.5e-09 36.1 0.4 1.6e-07 31.1 0.1 2.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CDJ97954.1 - 3.4e-05 23.8 0.0 0.00011 22.1 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 CDJ97954.1 - 0.019 14.2 0.0 0.047 12.9 0.0 1.6 1 0 0 1 1 1 0 Putative beta-lactamase-like family zf-C2H2 PF00096.26 CDJ97955.1 - 9.7e-10 38.4 13.7 0.0003 21.1 1.6 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ97955.1 - 3.1e-06 27.6 19.1 0.0016 19.1 0.9 4.4 5 0 0 5 5 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CDJ97955.1 - 0.00013 22.2 0.9 1.3 9.3 0.0 3.8 3 1 0 3 3 3 1 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 CDJ97955.1 - 0.022 15.0 1.1 5.2 7.5 0.6 3.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CDJ97955.1 - 0.026 14.5 13.0 0.65 10.1 2.9 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CDJ97955.1 - 0.034 14.8 3.8 2.1 9.0 0.2 3.4 3 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats DUF629 PF04780.12 CDJ97955.1 - 0.043 12.4 0.8 0.15 10.5 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF629) zf-C2H2_aberr PF17017.5 CDJ97955.1 - 0.07 13.3 7.7 0.16 12.1 0.0 3.3 4 0 0 4 4 3 0 Aberrant zinc-finger zf-C2HE PF16278.5 CDJ97955.1 - 0.14 12.7 1.8 3.4 8.2 0.1 3.3 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 CDJ97955.1 - 0.24 11.2 7.4 1.2 9.0 4.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-Di19 PF05605.12 CDJ97955.1 - 0.75 10.1 5.0 1.4 9.3 0.4 3.0 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf_Hakai PF18408.1 CDJ97955.1 - 0.81 9.4 0.0 0.81 9.4 0.0 2.5 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain DUF5339 PF17274.2 CDJ97955.1 - 0.89 10.5 5.7 1.9 9.4 0.0 2.8 3 0 0 3 3 2 0 Family of unknown function (DUF5339) FOXP-CC PF16159.5 CDJ97955.1 - 1.4 9.6 0.0 1.4 9.6 0.0 4.0 5 0 0 5 5 4 0 FOXP coiled-coil domain Kelch_4 PF13418.6 CDJ97956.1 - 2.1e-21 75.6 1.0 1.6e-06 28.0 0.0 5.3 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ97956.1 - 6e-21 74.2 0.7 8.1e-06 26.0 0.0 6.3 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 CDJ97956.1 - 1.9e-19 69.0 1.5 6.8e-05 22.4 0.0 5.5 5 1 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 CDJ97956.1 - 2.4e-19 68.9 1.4 5.6e-06 26.5 0.0 5.9 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 CDJ97956.1 - 2.1e-12 46.7 4.1 0.00048 20.1 0.0 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 CDJ97956.1 - 4e-10 39.2 10.1 0.0078 16.2 0.7 6.6 6 1 0 6 6 6 3 Kelch motif EF-hand_1 PF00036.32 CDJ97957.1 - 4.7e-07 28.9 10.3 0.0078 15.7 1.0 4.2 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 CDJ97957.1 - 6.3e-07 28.8 4.4 0.02 14.8 0.9 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CDJ97957.1 - 6.5e-07 29.1 12.8 0.00065 19.5 0.1 4.7 5 1 0 5 5 5 2 EF-hand domain pair EF-hand_7 PF13499.6 CDJ97957.1 - 1.2e-05 25.7 9.5 0.94 10.0 6.6 4.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CDJ97957.1 - 0.0029 17.0 8.6 0.34 10.5 0.2 3.3 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 CDJ97957.1 - 0.0097 15.8 0.4 4.8 7.2 0.1 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand TGT PF01702.18 CDJ97957.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase AAA_33 PF13671.6 CDJ97958.1 - 6.9e-24 84.6 0.0 1.3e-23 83.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain SPRY PF00622.28 CDJ97958.1 - 3.7e-13 49.7 0.1 7.1e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 SPRY domain Roc PF08477.13 CDJ97958.1 - 0.021 15.1 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 CDJ97958.1 - 0.19 11.1 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Nop16 PF09420.10 CDJ97958.1 - 1.9 8.5 6.5 0.2 11.6 2.0 1.6 2 0 0 2 2 2 0 Ribosome biogenesis protein Nop16 7TM_GPCR_Srx PF10328.9 CDJ97959.1 - 1.4e-20 74.0 2.9 1.7e-20 73.7 2.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Collagen PF01391.18 CDJ97961.1 - 8.5e-45 150.3 200.2 4.9e-08 32.6 37.8 7.7 3 2 2 5 5 5 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ97961.1 - 8.3e-21 73.8 9.8 7e-13 48.4 2.4 2.1 2 0 0 2 2 2 2 Nematode cuticle collagen N-terminal domain DUF229 PF02995.17 CDJ97962.1 - 2.3e-58 198.0 0.4 3.3e-58 197.5 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 CDJ97962.1 - 6.5e-06 25.7 0.1 9.7e-06 25.2 0.1 1.2 1 0 0 1 1 1 1 Sulfatase DUF1501 PF07394.12 CDJ97962.1 - 0.0029 16.7 0.5 0.0044 16.1 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Phosphodiest PF01663.22 CDJ97962.1 - 0.0051 16.4 0.1 0.0081 15.8 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase CpXC PF14353.6 CDJ97962.1 - 0.019 15.0 1.0 7.3 6.7 0.1 2.6 2 0 0 2 2 2 0 CpXC protein zf-C2H2 PF00096.26 CDJ97962.1 - 0.022 15.2 0.7 0.022 15.2 0.7 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-CSL PF05207.13 CDJ97962.1 - 0.03 14.0 3.8 0.83 9.4 0.1 2.9 2 1 0 2 2 2 0 CSL zinc finger zf-C2H2_4 PF13894.6 CDJ97962.1 - 0.12 13.2 0.6 0.12 13.2 0.6 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger Trm112p PF03966.16 CDJ97962.1 - 0.14 12.7 0.2 19 5.9 0.2 3.0 1 1 1 2 2 2 0 Trm112p-like protein A2L_zn_ribbon PF08792.10 CDJ97962.1 - 0.15 11.8 1.9 0.26 11.1 0.1 2.4 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-H2C2_2 PF13465.6 CDJ97962.1 - 0.22 12.0 7.7 1.6 9.3 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger double domain Metalloenzyme PF01676.18 CDJ97962.1 - 0.24 10.7 0.4 0.84 8.9 0.4 1.7 2 0 0 2 2 2 0 Metalloenzyme superfamily p450 PF00067.22 CDJ97964.1 - 5.4e-140 467.2 2.5 2.2e-87 293.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 SIL1 PF16782.5 CDJ97964.1 - 0.00057 19.2 2.6 0.00057 19.2 2.6 2.3 2 0 0 2 2 2 2 Nucleotide exchange factor SIL1 Transcrip_act PF04949.13 CDJ97964.1 - 0.055 13.4 1.0 5.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Transcriptional activator DUF5353 PF17304.2 CDJ97965.1 - 0.02 14.6 0.1 0.085 12.6 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5353) DUF1772 PF08592.11 CDJ97965.1 - 0.052 13.9 0.1 0.12 12.7 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) GWT1 PF06423.12 CDJ97965.1 - 0.36 10.9 3.2 0.21 11.7 1.1 1.6 2 0 0 2 2 2 0 GWT1 Galactosyl_T PF01762.21 CDJ97966.1 - 4.7e-73 245.2 0.1 3.3e-37 128.2 0.0 2.2 2 0 0 2 2 2 2 Galactosyltransferase Pou PF00157.17 CDJ97967.1 - 2.3e-30 104.4 0.0 3.9e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 CDJ97967.1 - 1.3e-17 63.4 1.8 3.7e-17 61.9 1.8 1.8 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 CDJ97967.1 - 8.6e-05 22.8 0.1 0.032 14.6 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_3 PF01381.22 CDJ97967.1 - 0.13 12.3 0.1 26 4.9 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix Ssl1 PF04056.14 CDJ97969.1 - 2.8e-77 258.9 0.3 4.5e-77 258.2 0.3 1.3 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 CDJ97969.1 - 4.5e-12 46.6 0.1 8.2e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 CDJ97969.1 - 1.1e-07 32.3 0.1 1.6e-07 31.7 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.12 CDJ97969.1 - 1.3e-07 31.7 12.5 1.3e-07 31.7 12.5 3.0 2 1 0 2 2 2 1 TFIIH C1-like domain DZR PF12773.7 CDJ97969.1 - 0.00046 20.1 15.8 0.0044 17.0 9.0 2.7 2 0 0 2 2 2 2 Double zinc ribbon VWA_3 PF13768.6 CDJ97969.1 - 0.0047 16.9 0.0 0.012 15.5 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain C1_2 PF03107.16 CDJ97969.1 - 0.0065 16.8 1.9 0.0065 16.8 1.9 2.9 2 1 0 2 2 2 1 C1 domain zf-C2HC5 PF06221.13 CDJ97969.1 - 0.64 10.1 26.6 0.92 9.5 11.7 2.7 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-C2H2_6 PF13912.6 CDJ97969.1 - 0.87 9.7 5.6 3.8 7.6 0.0 4.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-ACC PF17848.1 CDJ97969.1 - 3.1 8.0 12.4 0.89 9.7 1.1 4.1 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain GrpE PF01025.19 CDJ97970.1 - 6.9e-45 152.7 1.0 8.4e-45 152.4 0.6 1.3 1 1 0 1 1 1 1 GrpE SHE3 PF17078.5 CDJ97970.1 - 0.075 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF4473 PF14747.6 CDJ97970.1 - 0.16 12.5 1.1 0.29 11.7 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) Metallophos PF00149.28 CDJ97971.1 - 7.7e-34 118.0 0.1 1e-33 117.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 CDJ97971.1 - 0.029 14.0 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF5378 PF17349.2 CDJ97971.1 - 0.072 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) p450 PF00067.22 CDJ97972.1 - 5.4e-140 467.2 2.5 2.2e-87 293.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 SIL1 PF16782.5 CDJ97972.1 - 0.00057 19.2 2.6 0.00057 19.2 2.6 2.3 2 0 0 2 2 2 2 Nucleotide exchange factor SIL1 Transcrip_act PF04949.13 CDJ97972.1 - 0.055 13.4 1.0 5.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Transcriptional activator DUF5353 PF17304.2 CDJ97973.1 - 0.02 14.6 0.1 0.085 12.6 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5353) DUF1772 PF08592.11 CDJ97973.1 - 0.052 13.9 0.1 0.12 12.7 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) GWT1 PF06423.12 CDJ97973.1 - 0.36 10.9 3.2 0.21 11.7 1.1 1.6 2 0 0 2 2 2 0 GWT1 Galactosyl_T PF01762.21 CDJ97974.1 - 4.7e-73 245.2 0.1 3.3e-37 128.2 0.0 2.2 2 0 0 2 2 2 2 Galactosyltransferase Pou PF00157.17 CDJ97975.1 - 2.3e-30 104.4 0.0 3.9e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 CDJ97975.1 - 1.3e-17 63.4 1.8 3.7e-17 61.9 1.8 1.8 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 CDJ97975.1 - 8.6e-05 22.8 0.1 0.032 14.6 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_3 PF01381.22 CDJ97975.1 - 0.13 12.3 0.1 26 4.9 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix Ssl1 PF04056.14 CDJ97977.1 - 2.8e-77 258.9 0.3 4.5e-77 258.2 0.3 1.3 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 CDJ97977.1 - 4.5e-12 46.6 0.1 8.2e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 CDJ97977.1 - 1.1e-07 32.3 0.1 1.6e-07 31.7 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.12 CDJ97977.1 - 1.3e-07 31.7 12.5 1.3e-07 31.7 12.5 3.0 2 1 0 2 2 2 1 TFIIH C1-like domain DZR PF12773.7 CDJ97977.1 - 0.00046 20.1 15.8 0.0044 17.0 9.0 2.7 2 0 0 2 2 2 2 Double zinc ribbon VWA_3 PF13768.6 CDJ97977.1 - 0.0047 16.9 0.0 0.012 15.5 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain C1_2 PF03107.16 CDJ97977.1 - 0.0065 16.8 1.9 0.0065 16.8 1.9 2.9 2 1 0 2 2 2 1 C1 domain zf-C2HC5 PF06221.13 CDJ97977.1 - 0.64 10.1 26.6 0.92 9.5 11.7 2.7 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-C2H2_6 PF13912.6 CDJ97977.1 - 0.87 9.7 5.6 3.8 7.6 0.0 4.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-ACC PF17848.1 CDJ97977.1 - 3.1 8.0 12.4 0.89 9.7 1.1 4.1 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain GrpE PF01025.19 CDJ97978.1 - 6.9e-45 152.7 1.0 8.4e-45 152.4 0.6 1.3 1 1 0 1 1 1 1 GrpE SHE3 PF17078.5 CDJ97978.1 - 0.075 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF4473 PF14747.6 CDJ97978.1 - 0.16 12.5 1.1 0.29 11.7 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) Metallophos PF00149.28 CDJ97979.1 - 7.7e-34 118.0 0.1 1e-33 117.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 CDJ97979.1 - 0.029 14.0 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF5378 PF17349.2 CDJ97979.1 - 0.072 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) TPR_14 PF13428.6 CDJ97980.1 - 0.00011 22.7 0.6 17 6.6 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat Mcl1_mid PF12341.8 CDJ97980.1 - 0.042 13.2 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region TPR_16 PF13432.6 CDJ97980.1 - 0.11 13.2 0.0 0.58 10.9 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat LUC7 PF03194.15 CDJ97981.1 - 7e-70 235.6 13.6 8.9e-70 235.2 13.6 1.1 1 0 0 1 1 1 1 LUC7 N_terminus Annexin PF00191.20 CDJ97982.1 - 1e-76 252.9 10.0 9.1e-24 83.3 0.2 4.1 4 0 0 4 4 4 4 Annexin Ribosomal_S6e PF01092.19 CDJ97982.1 - 0.0029 17.6 0.1 19 5.2 0.0 3.3 3 0 0 3 3 3 2 Ribosomal protein S6e Spore_III_AB PF09548.10 CDJ97982.1 - 0.053 13.6 0.5 6.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) PRMT5_C PF17286.2 CDJ97983.1 - 1.7e-42 145.3 0.1 2.3e-42 144.8 0.1 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain PRMT5 PF05185.16 CDJ97983.1 - 2.1e-14 53.7 0.0 3e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase MRP-S26 PF14943.6 CDJ97984.1 - 1.6e-44 151.8 13.2 2e-44 151.5 13.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 DUF4192 PF13830.6 CDJ97984.1 - 0.013 15.6 7.2 0.019 15.0 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) DNTTIP1_dimer PF18192.1 CDJ97984.1 - 0.12 12.8 0.9 0.3 11.5 0.9 1.6 1 0 0 1 1 1 0 DNTTIP1 dimerisation domain DUF1682 PF07946.14 CDJ97984.1 - 0.15 11.2 6.6 0.2 10.9 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Pex2_Pex12 PF04757.14 CDJ97985.1 - 2.5e-23 82.9 6.0 3e-23 82.6 6.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.6 CDJ97985.1 - 3.6e-07 30.0 8.1 5.9e-07 29.3 8.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDJ97985.1 - 3.6e-06 26.9 8.6 6.6e-06 26.1 8.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDJ97985.1 - 6.2e-06 26.0 4.7 9.7e-06 25.4 4.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ97985.1 - 7.1e-06 25.8 8.4 1.1e-05 25.2 8.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ97985.1 - 9.3e-06 25.4 9.1 1.4e-05 24.8 9.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ97985.1 - 1.8e-05 25.0 10.5 2.7e-05 24.4 10.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 CDJ97985.1 - 4.5e-05 23.5 8.3 8.5e-05 22.6 8.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CDJ97985.1 - 0.00033 20.5 7.9 0.00055 19.7 7.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CDJ97985.1 - 0.027 14.3 5.4 0.047 13.5 5.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF676 PF05057.14 CDJ97985.1 - 0.16 11.4 0.3 12 5.4 0.0 2.4 3 0 0 3 3 3 0 Putative serine esterase (DUF676) HscB_4_cys PF18256.1 CDJ97985.1 - 0.22 11.3 7.0 0.61 9.9 7.0 1.8 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif zf-RING_11 PF17123.5 CDJ97985.1 - 0.37 10.6 4.6 1.1 9.0 4.6 1.9 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_10 PF16685.5 CDJ97985.1 - 1.7 8.9 4.6 3.1 8.0 4.6 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 CDJ97985.1 - 2.3 8.6 9.9 4.1 7.8 9.9 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain tRNA-synt_1b PF00579.25 CDJ97986.1 - 1.1e-61 208.8 0.0 1.5e-61 208.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) RasGEF PF00617.19 CDJ97989.1 - 7.5e-41 140.3 0.0 1.4e-40 139.4 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain cNMP_binding PF00027.29 CDJ97989.1 - 7.3e-16 58.0 0.0 2.3e-15 56.4 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DEP PF00610.21 CDJ97989.1 - 3.7e-10 39.7 0.0 9.1e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RasGEF_N PF00618.20 CDJ97989.1 - 3e-07 30.6 0.0 7.3e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif fn3 PF00041.21 CDJ97990.1 - 4.9e-14 52.4 0.1 4.3e-05 23.8 0.0 3.4 3 0 0 3 3 3 3 Fibronectin type III domain Aa_trans PF01490.18 CDJ97991.1 - 4.6e-27 94.8 37.5 1e-25 90.3 37.5 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CDJ97991.1 - 2.6e-07 30.0 3.3 2.6e-07 30.0 3.3 2.8 2 1 1 3 3 3 1 Tryptophan/tyrosine permease family NADHdh-2_N PF12155.8 CDJ97991.1 - 0.087 13.2 5.9 0.11 12.9 0.5 2.9 3 0 0 3 3 3 0 NADH dehydrogenase subunit 2 N-terminal MttA_Hcf106 PF02416.16 CDJ97991.1 - 0.2 11.0 1.4 4.5 6.7 0.7 2.5 2 0 0 2 2 2 0 mttA/Hcf106 family DUF4267 PF14087.6 CDJ97991.1 - 2.4 8.3 6.4 1.2 9.2 0.2 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4267) DUF2367 PF10164.9 CDJ97991.1 - 3.1 8.3 5.4 0.85 10.1 0.6 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) Collagen PF01391.18 CDJ97994.1 - 2.4e-28 97.7 131.7 3.4e-08 33.1 38.2 4.5 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ97994.1 - 4.2e-09 36.3 0.5 5.4e-09 36.0 0.5 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Cortexin PF11057.8 CDJ97995.1 - 0.055 13.3 0.1 0.8 9.6 0.0 2.2 2 0 0 2 2 2 0 Cortexin of kidney Recep_L_domain PF01030.24 CDJ97995.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Receptor L domain Peptidase_M18 PF02127.15 CDJ97996.1 - 9.5e-181 601.3 0.0 2.6e-113 379.1 0.0 2.2 2 0 0 2 2 2 2 Aminopeptidase I zinc metalloprotease (M18) BTB PF00651.31 CDJ97996.1 - 3.8e-26 91.5 0.0 7.4e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Peptidase_M42 PF05343.14 CDJ97996.1 - 9.1e-09 34.7 2.5 1e-06 28.0 0.2 2.9 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase Prefoldin PF02996.17 CDJ97996.1 - 0.41 10.6 1.9 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 Prefoldin subunit PROCN PF08083.11 CDJ97997.1 - 5.3e-233 773.0 7.8 5.3e-233 773.0 7.8 2.1 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 CDJ97997.1 - 1.1e-126 421.0 1.3 2.1e-126 420.2 1.3 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 CDJ97997.1 - 1.8e-89 297.8 2.0 5.2e-89 296.2 2.0 1.9 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 CDJ97997.1 - 9.4e-88 291.9 4.7 9.4e-88 291.9 4.7 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 CDJ97997.1 - 2.4e-73 244.5 0.1 5.2e-73 243.4 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 CDJ97997.1 - 3e-50 169.2 0.1 8.4e-50 167.8 0.1 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 CDJ97997.1 - 9.8e-47 157.2 1.2 1.7e-46 156.5 0.3 2.0 2 0 0 2 2 2 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 CDJ97997.1 - 5e-07 29.7 0.0 1.5e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF3337 PF11816.8 CDJ97998.1 - 1.7e-38 132.2 0.1 3.2e-38 131.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 CDJ97998.1 - 5.1e-28 96.8 6.3 1.1e-05 26.0 0.0 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ97998.1 - 1.8e-06 28.1 1.9 0.089 13.1 0.1 4.1 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ97998.1 - 0.00064 18.8 1.3 0.15 11.0 0.0 2.4 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CDJ97998.1 - 0.027 13.1 6.5 0.57 8.7 0.1 3.0 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Proteasom_PSMB PF10508.9 CDJ97999.1 - 8.5e-18 64.1 1.6 9.6e-18 64.0 1.6 1.0 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit Sigma54_CBD PF04963.13 CDJ97999.1 - 0.028 14.3 0.1 0.063 13.1 0.1 1.5 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain Hormone_6 PF00236.18 CDJ97999.1 - 0.037 14.0 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 Glycoprotein hormone Drf_FH3 PF06367.16 CDJ97999.1 - 0.075 12.6 0.8 0.15 11.7 0.3 1.8 1 1 1 2 2 2 0 Diaphanous FH3 Domain Coat_F PF07875.12 CDJ97999.1 - 0.15 12.3 3.9 0.49 10.7 0.8 2.8 2 1 0 2 2 2 0 Coat F domain SNAPc_SNAP43 PF09808.9 CDJ98000.1 - 9.8e-31 107.2 0.0 1.5e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Tht1 PF04163.12 CDJ98000.1 - 0.0055 15.5 0.3 0.0073 15.1 0.3 1.1 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein Patched PF02460.18 CDJ98001.1 - 5.7e-249 828.5 10.7 6.6e-249 828.3 10.7 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 CDJ98001.1 - 8.8e-40 136.0 7.3 1.9e-36 125.2 3.4 3.3 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 CDJ98001.1 - 0.00063 18.8 3.0 0.00063 18.8 3.0 2.4 2 0 0 2 2 2 1 MMPL family SecD_SecF PF02355.16 CDJ98001.1 - 0.0013 18.1 8.7 0.0013 18.1 8.7 2.8 3 0 0 3 3 3 1 Protein export membrane protein Ank_2 PF12796.7 CDJ98002.1 - 3.4e-14 53.2 0.1 9.6e-14 51.7 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ98002.1 - 8e-14 51.8 0.1 1.3e-09 38.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ98002.1 - 9.1e-11 41.0 0.0 0.0043 17.4 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat BRCT_2 PF16589.5 CDJ98002.1 - 6.6e-10 39.3 0.1 2.9e-05 24.4 0.0 3.8 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain Ank_5 PF13857.6 CDJ98002.1 - 1.8e-08 34.5 0.1 0.0063 16.8 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CDJ98002.1 - 1.6e-07 31.5 0.0 0.00084 19.7 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat BRCT PF00533.26 CDJ98002.1 - 0.00011 22.5 0.0 0.59 10.5 0.0 3.7 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain zf-C3HC4_2 PF13923.6 CDJ98002.1 - 0.00027 20.7 2.4 0.00096 18.9 2.4 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ98002.1 - 0.0014 18.6 2.2 0.0053 16.7 2.2 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDJ98002.1 - 0.006 16.7 3.1 0.018 15.2 3.1 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CDJ98002.1 - 0.021 14.8 12.2 0.11 12.5 12.2 2.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 CDJ98002.1 - 0.026 14.4 9.2 0.08 12.8 9.2 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) BRCT_3 PF18428.1 CDJ98002.1 - 0.041 14.0 0.0 0.64 10.1 0.0 2.5 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CDJ98002.1 - 0.18 12.1 1.1 22 5.5 0.0 3.3 4 0 0 4 4 3 0 DNA ligase 3 BRCT domain zf-rbx1 PF12678.7 CDJ98002.1 - 0.62 10.4 8.5 2.6 8.4 8.5 2.1 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CDJ98002.1 - 0.7 9.8 6.8 2.8 7.9 6.8 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 IBR PF01485.21 CDJ98002.1 - 5.7 7.3 11.5 42 4.5 11.6 2.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain EGF_CA PF07645.15 CDJ98004.1 - 0.00011 22.3 6.3 0.00011 22.3 6.3 2.6 2 1 0 2 2 2 1 Calcium-binding EGF domain EB PF01683.18 CDJ98004.1 - 1.6 9.1 15.0 0.093 13.0 5.7 2.3 1 1 1 2 2 2 0 EB module PQ-loop PF04193.14 CDJ98005.1 - 1.6e-20 72.6 15.6 5.3e-12 45.3 3.2 3.2 3 1 0 3 3 3 2 PQ loop repeat Aa_trans PF01490.18 CDJ98006.1 - 1.6e-14 53.4 24.4 2.1e-14 53.0 24.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1418 PF07214.12 CDJ98006.1 - 0.51 10.2 4.1 11 5.9 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1418) TPR_14 PF13428.6 CDJ98007.1 - 9.7e-05 22.9 2.2 0.27 12.2 0.1 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ98007.1 - 0.0066 16.9 1.7 0.81 10.2 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat PAS PF00989.25 CDJ98008.1 - 1.1e-09 38.3 0.0 3.2e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 CDJ98008.1 - 1.3e-07 31.8 0.0 0.0005 20.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 CDJ98008.1 - 2.6e-07 30.7 0.0 0.00013 22.0 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_9 PF13426.7 CDJ98008.1 - 4.7e-06 26.8 0.0 9.8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_2 PF08446.11 CDJ98008.1 - 0.0077 16.9 0.0 0.024 15.3 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 CDJ98008.1 - 0.012 15.8 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 PAS fold KIP1 PF07765.12 CDJ98008.1 - 0.14 12.3 0.2 0.34 11.0 0.2 1.6 1 0 0 1 1 1 0 KIP1-like protein Skp1_POZ PF03931.15 CDJ98009.1 - 1.5e-14 53.9 0.4 3.2e-14 52.8 0.2 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain RVT_1 PF00078.27 CDJ98010.1 - 4.7e-19 68.8 0.0 8.3e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CDJ98010.1 - 1.8e-08 34.8 0.0 4e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ98010.1 - 7.3e-08 33.0 0.0 1.8e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ98010.1 - 1.5e-05 25.2 0.0 3.7e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Meth_synt_1 PF08267.12 CDJ98011.1 - 0.025 14.1 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain Forkhead PF00250.18 CDJ98012.1 - 2.5e-35 120.6 0.0 3.5e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Forkhead domain DUF2890 PF11081.8 CDJ98012.1 - 0.15 12.1 0.2 0.28 11.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Granulin PF00396.18 CDJ98013.1 - 0.026 14.8 2.7 0.071 13.5 1.1 2.3 2 0 0 2 2 2 0 Granulin SOBP PF15279.6 CDJ98013.1 - 0.055 14.1 1.9 0.069 13.8 1.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Presenilin PF01080.17 CDJ98013.1 - 0.43 9.3 7.0 0.58 8.9 7.0 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_S64 PF08192.11 CDJ98013.1 - 2.5 6.5 4.5 2.9 6.3 4.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 Rrn6 PF10214.9 CDJ98013.1 - 5.9 5.2 14.2 8.3 4.8 14.2 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Sod_Fe_C PF02777.18 CDJ98014.1 - 5.8e-36 122.7 0.1 1.2e-35 121.8 0.0 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CDJ98014.1 - 8.8e-33 112.6 3.2 1.5e-32 111.9 3.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF2892 PF11127.8 CDJ98014.1 - 0.2 11.7 0.1 0.36 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) GLTP PF08718.11 CDJ98015.1 - 2.9e-37 128.2 0.0 3.8e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) HEPN_DZIP3 PF18738.1 CDJ98016.1 - 0.048 13.4 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 DZIP3/ hRUL138-like HEPN WD40 PF00400.32 CDJ98016.1 - 0.057 14.3 0.1 1.2 10.1 0.0 3.3 2 0 0 2 2 2 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ98016.1 - 0.12 12.7 0.7 12 6.3 0.0 3.9 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Sporozoite_P67 PF05642.11 CDJ98017.1 - 0.44 8.6 11.0 0.49 8.4 11.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3482 PF11981.8 CDJ98017.1 - 2.7 7.3 7.0 3.6 6.9 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) JmjC PF02373.22 CDJ98018.1 - 7.7e-20 71.4 0.9 1.4e-19 70.6 0.3 1.8 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CDJ98018.1 - 1.5e-18 67.5 0.4 2.2e-17 63.6 0.4 2.2 1 1 0 1 1 1 1 Cupin-like domain SIR4_SID PF16991.5 CDJ98018.1 - 1.2 9.2 4.9 12 5.9 0.0 2.8 2 1 0 2 2 2 0 Sir4 SID domain JmjC PF02373.22 CDJ98019.1 - 2.7e-17 63.2 0.3 5.5e-17 62.2 0.3 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CDJ98019.1 - 2.1e-14 53.9 0.3 2.1e-14 53.9 0.3 2.4 2 1 0 2 2 2 1 Cupin-like domain Mpp10 PF04006.12 CDJ98019.1 - 0.00054 18.5 13.0 0.00084 17.9 13.0 1.2 1 0 0 1 1 1 1 Mpp10 protein DUF3725 PF12523.8 CDJ98019.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) AAA_22 PF13401.6 CDJ98019.1 - 0.17 12.1 0.0 0.57 10.5 0.0 1.7 1 1 0 2 2 2 0 AAA domain THOC2_N PF16134.5 CDJ98019.1 - 0.37 9.4 1.9 0.55 8.8 1.9 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Na_trans_assoc PF06512.13 CDJ98019.1 - 0.62 10.3 14.7 1 9.6 14.7 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.12 CDJ98019.1 - 0.85 7.8 23.1 1.3 7.2 23.1 1.1 1 0 0 1 1 1 0 Nop14-like family Glypican PF01153.19 CDJ98019.1 - 0.9 8.3 3.4 0.71 8.6 2.4 1.3 1 1 0 1 1 1 0 Glypican PPP4R2 PF09184.11 CDJ98019.1 - 1.6 8.2 22.3 2.9 7.4 22.3 1.4 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 CDJ98019.1 - 3.3 7.0 26.4 4.5 6.5 26.4 1.1 1 0 0 1 1 1 0 BUD22 PNISR PF15996.5 CDJ98019.1 - 7.9 6.7 15.7 12 6.1 15.7 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Sporozoite_P67 PF05642.11 CDJ98019.1 - 9.5 4.2 17.2 15 3.5 17.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_transf_43 PF03360.16 CDJ98020.1 - 1.2e-50 172.2 0.0 1.4e-50 172.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 Motile_Sperm PF00635.26 CDJ98021.1 - 2e-21 75.9 0.0 2.2e-21 75.7 0.0 1.0 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Globin PF00042.22 CDJ98022.1 - 1.1e-14 54.9 0.0 1.5e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Globin SART-1 PF03343.13 CDJ98024.1 - 1.9e-76 258.0 44.4 1.9e-76 258.0 44.4 2.2 2 0 0 2 2 2 1 SART-1 family Bromodomain PF00439.25 CDJ98025.1 - 5.1e-20 71.3 0.0 1.1e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 Bromodomain MBD PF01429.19 CDJ98025.1 - 8.3e-18 63.9 0.0 1.8e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Methyl-CpG binding domain WSD PF15613.6 CDJ98025.1 - 2.9e-14 53.3 1.0 3.2e-12 46.8 0.0 3.5 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD PF00628.29 CDJ98025.1 - 8.3e-07 28.8 31.9 0.00032 20.5 14.5 2.9 2 0 0 2 2 2 2 PHD-finger WHIM1 PF15612.6 CDJ98025.1 - 7.3e-05 22.2 0.1 0.00018 20.9 0.1 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DDT PF02791.17 CDJ98025.1 - 0.00039 20.7 0.1 0.0019 18.5 0.1 2.2 1 0 0 1 1 1 1 DDT domain Flagellin_IN PF07196.13 CDJ98025.1 - 0.14 12.3 0.9 0.41 10.9 0.9 1.7 1 0 0 1 1 1 0 Flagellin hook IN motif DEC-1_N PF04625.13 CDJ98025.1 - 0.4 9.6 7.3 0.76 8.7 7.3 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region PHD_2 PF13831.6 CDJ98025.1 - 1.2 8.7 19.3 2.7 7.6 7.2 2.8 2 0 0 2 2 2 0 PHD-finger CAP_N PF01213.19 CDJ98025.1 - 1.5 8.3 5.7 4.5 6.7 5.7 1.8 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF5082 PF16888.5 CDJ98025.1 - 4.3 7.6 6.5 1.1 9.6 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) zf-RING_2 PF13639.6 CDJ98025.1 - 7.7 6.9 33.2 3.5 8.1 9.1 2.8 2 0 0 2 2 2 0 Ring finger domain PNP_UDP_1 PF01048.20 CDJ98026.1 - 7.6e-29 100.6 0.0 9.4e-29 100.3 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Pkinase PF00069.25 CDJ98027.1 - 4.8e-24 85.1 0.7 5.8e-24 84.9 0.7 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ98027.1 - 1.7e-14 53.8 0.1 2e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ98027.1 - 1.4e-05 24.1 0.0 2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDJ98027.1 - 0.0014 18.6 0.0 0.0058 16.6 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family UspB PF10625.9 CDJ98027.1 - 0.35 10.8 2.6 3.3 7.7 0.4 2.2 2 0 0 2 2 2 0 Universal stress protein B (UspB) SCVP PF17619.2 CDJ98028.1 - 1.2e-08 35.7 0.1 1.3e-08 35.5 0.1 1.1 1 0 0 1 1 1 1 Secreted clade V proteins Pneumo_M2 PF07380.11 CDJ98028.1 - 0.1 12.9 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Pneumovirus M2 protein SCVP PF17619.2 CDJ98029.1 - 2.2e-17 63.7 0.1 6e-10 39.9 0.0 2.1 2 0 0 2 2 2 2 Secreted clade V proteins Herpes_teg_N PF04843.12 CDJ98029.1 - 0.038 13.7 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Herpesvirus tegument protein, N-terminal conserved region ShK PF01549.24 CDJ98030.1 - 3e-46 155.7 75.6 1.1e-09 38.6 6.1 6.2 6 0 0 6 6 6 5 ShK domain-like DUF5332 PF17266.2 CDJ98031.1 - 5.2e-52 175.5 14.1 5.2e-52 175.5 14.1 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5332) Fe-ADH PF00465.19 CDJ98032.1 - 1.9e-85 286.8 0.0 1.1e-71 241.5 0.0 2.0 1 1 1 2 2 2 2 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 CDJ98032.1 - 8.6e-06 25.6 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Rrp15p PF07890.12 CDJ98033.1 - 4.7e-13 49.6 18.8 7.7e-13 48.9 18.5 1.5 1 1 0 1 1 1 1 Rrp15p DUF4743 PF15916.5 CDJ98033.1 - 0.098 12.6 1.3 0.16 11.9 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4743) DUF1524 PF07510.11 CDJ98033.1 - 1.2 9.0 8.1 4.3 7.2 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1524) Tautomerase PF01361.21 CDJ98033.1 - 1.3 9.0 4.4 1.7 8.6 0.3 2.4 2 0 0 2 2 2 0 Tautomerase enzyme DUF4538 PF15061.6 CDJ98034.1 - 0.041 13.6 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Acetyltransf_1 PF00583.25 CDJ98035.1 - 6e-13 49.1 0.1 7.5e-13 48.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDJ98035.1 - 5.9e-10 39.2 0.1 8.6e-10 38.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDJ98035.1 - 6.1e-09 36.2 0.1 8.3e-09 35.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDJ98035.1 - 1.9e-07 31.0 0.0 3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 CDJ98035.1 - 0.00014 22.0 0.2 0.0002 21.5 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CDJ98035.1 - 0.0081 16.3 0.1 0.011 15.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4149 PF13664.6 CDJ98036.1 - 0.037 14.3 0.3 0.045 14.1 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) DUF4536 PF15055.6 CDJ98037.1 - 0.001 19.3 0.4 0.0013 18.9 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4536) DUF3493 PF11998.8 CDJ98037.1 - 0.099 12.8 0.1 0.15 12.3 0.1 1.2 1 0 0 1 1 1 0 Low psii accumulation1 / Rep27 SKI PF01202.22 CDJ98038.1 - 4.7e-16 59.3 0.0 5.4e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 CDJ98038.1 - 2.2e-07 31.1 0.0 4e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CDJ98038.1 - 4.3e-06 27.3 0.4 1.4e-05 25.6 0.2 1.9 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 CDJ98038.1 - 0.0028 17.5 1.0 0.24 11.3 0.1 2.2 1 1 1 2 2 2 1 Deoxynucleoside kinase tRNA_lig_kinase PF08303.11 CDJ98038.1 - 0.0051 16.9 0.0 0.014 15.5 0.0 1.7 2 0 0 2 2 2 1 tRNA ligase kinase domain AAA PF00004.29 CDJ98038.1 - 0.011 16.1 0.0 0.019 15.4 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ98038.1 - 0.016 15.6 0.0 0.034 14.5 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CDJ98038.1 - 0.018 15.3 0.0 0.037 14.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDJ98038.1 - 0.033 14.7 0.2 0.036 14.6 0.2 1.5 1 1 0 1 1 1 0 ABC transporter Rad17 PF03215.15 CDJ98038.1 - 0.038 13.9 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain DUF2075 PF09848.9 CDJ98038.1 - 0.05 12.8 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Cytidylate_kin PF02224.18 CDJ98038.1 - 0.062 13.0 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase RuvB_N PF05496.12 CDJ98038.1 - 0.091 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain PRK PF00485.18 CDJ98038.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Cytidylate_kin2 PF13189.6 CDJ98038.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA_17 PF13207.6 CDJ98038.1 - 0.17 12.3 0.3 0.58 10.6 0.1 2.2 2 1 0 2 2 2 0 AAA domain TbpB_C PF17483.2 CDJ98041.1 - 0.14 12.6 0.1 0.17 12.2 0.1 1.1 1 0 0 1 1 1 0 C-lobe handle domain of Tf-binding protein B Neur_chan_LBD PF02931.23 CDJ98047.1 - 1.3e-48 165.4 1.3 1.8e-48 164.8 0.5 1.6 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ98047.1 - 1.4e-30 107.2 3.2 1.3e-27 97.5 0.4 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region EF-hand_1 PF00036.32 CDJ98048.1 - 1e-30 102.9 13.0 6e-09 34.8 1.8 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ98048.1 - 2.3e-30 104.8 9.1 6.5e-18 64.9 2.7 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ98048.1 - 1.3e-26 90.2 9.4 9.3e-08 31.4 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CDJ98048.1 - 2e-22 78.8 8.0 1.5e-12 47.2 3.0 4.1 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 CDJ98048.1 - 3.1e-19 69.1 0.1 2.3e-09 37.5 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDJ98048.1 - 1.7e-13 49.4 13.3 6e-05 22.3 0.3 4.7 4 2 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 CDJ98048.1 - 7e-07 29.1 3.4 0.0015 18.5 0.1 2.4 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand PHB_acc_N PF07879.11 CDJ98048.1 - 0.0044 17.1 0.1 0.49 10.5 0.0 3.2 4 0 0 4 4 3 1 PHB/PHA accumulation regulator DNA-binding domain SPARC_Ca_bdg PF10591.9 CDJ98048.1 - 0.022 15.1 0.6 5.4 7.4 0.1 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Ribosomal_L18_c PF14204.6 CDJ98048.1 - 0.038 14.9 1.5 0.14 13.1 0.1 2.4 2 1 0 2 2 2 0 Ribosomal L18 C-terminal region Caleosin PF05042.13 CDJ98048.1 - 0.067 13.1 3.0 29 4.5 0.1 3.7 1 1 1 3 3 3 0 Caleosin related protein DDE_Tnp_ISL3 PF01610.17 CDJ98048.1 - 0.077 12.7 0.0 4.7 6.9 0.0 2.1 1 1 1 2 2 2 0 Transposase GPHH PF16905.5 CDJ98048.1 - 0.13 12.0 0.0 21 4.9 0.0 3.2 4 0 0 4 4 4 0 Voltage-dependent L-type calcium channel, IQ-associated DUF2666 PF10869.8 CDJ98048.1 - 0.15 12.3 0.6 2.3 8.4 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) MgtE_N PF03448.17 CDJ98048.1 - 0.43 11.2 4.6 3.9 8.1 0.2 2.6 1 1 0 2 2 2 0 MgtE intracellular N domain TerB PF05099.13 CDJ98048.1 - 0.61 10.0 5.0 5.7 6.9 0.5 2.8 1 1 3 4 4 4 0 Tellurite resistance protein TerB 7TM_GPCR_Srw PF10324.9 CDJ98049.1 - 1.4e-38 133.0 16.5 3e-38 131.9 16.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 CDJ98049.1 - 8.7e-05 22.0 0.4 8.7e-05 22.0 0.4 2.4 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDJ98049.1 - 0.0039 16.6 9.6 0.021 14.2 2.5 2.5 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx Jiraiya PF15038.6 CDJ98049.1 - 8.1 5.9 16.0 0.31 10.4 7.9 2.4 2 1 1 3 3 3 0 Jiraiya Acetyltransf_1 PF00583.25 CDJ98052.1 - 0.045 14.0 0.0 0.058 13.6 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family FPN1 PF06963.12 CDJ98055.1 - 4.2e-34 117.9 3.2 5e-34 117.6 3.2 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) MFS_1 PF07690.16 CDJ98055.1 - 1.7e-05 24.0 4.7 4.9e-05 22.4 4.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CDJ98055.1 - 0.038 12.8 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 MFS_1 like family DUF5357 PF17310.2 CDJ98055.1 - 0.086 11.4 1.6 0.12 10.9 1.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5357) PAP2_C PF14360.6 CDJ98059.1 - 2.3e-21 76.1 8.2 2.3e-21 76.1 8.2 3.0 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 CDJ98059.1 - 5.8e-07 29.3 2.7 5.8e-07 29.3 2.7 2.6 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 CDJ98059.1 - 0.39 10.4 11.5 0.039 13.6 6.6 1.7 2 0 0 2 2 2 0 PAP2 superfamily Glyco_hydro_18 PF00704.28 CDJ98060.1 - 5.5e-55 187.3 0.0 6.5e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Actin PF00022.19 CDJ98061.1 - 8.2e-151 502.2 0.0 2.9e-150 500.4 0.0 1.7 1 1 0 1 1 1 1 Actin BTB_2 PF02214.22 CDJ98062.1 - 8.9e-11 42.0 0.2 1.4e-10 41.4 0.2 1.3 1 0 0 1 1 1 1 BTB/POZ domain Gal-bind_lectin PF00337.22 CDJ98063.1 - 6.9e-24 83.9 0.4 8.5e-24 83.6 0.4 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin CDK5_activator PF03261.15 CDJ98064.1 - 2.8e-65 221.2 0.8 3.3e-65 221.0 0.8 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase 5 activator protein YqhR PF11085.8 CDJ98064.1 - 0.056 13.4 0.2 0.072 13.0 0.2 1.1 1 0 0 1 1 1 0 Conserved membrane protein YqhR PAN_1 PF00024.26 CDJ98066.1 - 6.4e-05 22.8 0.1 0.19 11.7 0.0 2.2 1 1 1 2 2 2 2 PAN domain Chromo PF00385.24 CDJ98069.1 - 2.9e-18 65.5 0.3 4.9e-15 55.2 0.2 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 CDJ98069.1 - 0.00071 19.6 0.0 0.65 10.1 0.0 2.4 2 0 0 2 2 2 2 Chromo shadow domain Mtf2_C PF14061.6 CDJ98069.1 - 0.12 12.6 0.1 0.31 11.2 0.1 1.7 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Hormone_recep PF00104.30 CDJ98070.1 - 8.9e-11 41.7 0.2 9.9e-11 41.6 0.2 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor LSM PF01423.22 CDJ98071.1 - 3.2e-21 74.8 0.2 4.3e-21 74.4 0.2 1.2 1 0 0 1 1 1 1 LSM domain Peptidase_M16_M PF16187.5 CDJ98071.1 - 0.066 12.5 0.1 0.094 12.0 0.1 1.2 1 0 0 1 1 1 0 Middle or third domain of peptidase_M16 PAXX PF15384.6 CDJ98071.1 - 0.096 12.4 0.1 0.12 12.0 0.1 1.1 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 LNS2 PF08235.13 CDJ98071.1 - 0.097 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) YfkB PF08756.10 CDJ98071.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 YfkB-like domain Med9 PF07544.13 CDJ98072.1 - 3.6e-06 27.0 2.5 4.8e-06 26.6 2.5 1.3 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 XLF PF09302.11 CDJ98072.1 - 0.13 12.4 1.1 0.21 11.7 1.1 1.4 1 1 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component RRS1 PF04939.12 CDJ98073.1 - 2.5e-50 170.5 8.0 2.5e-50 170.5 8.0 2.3 2 1 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) Trp_dioxygenase PF03301.13 CDJ98073.1 - 0.71 9.1 11.4 0.088 12.1 7.2 1.6 2 0 0 2 2 2 0 Tryptophan 2,3-dioxygenase I-set PF07679.16 CDJ98076.1 - 2.2e-17 62.9 0.0 2e-16 59.8 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ98076.1 - 7.8e-17 61.6 0.1 2.2e-14 53.8 0.0 2.3 2 1 0 2 2 2 1 Immunoglobulin domain fn3 PF00041.21 CDJ98076.1 - 7e-15 55.1 0.4 1.7e-14 53.9 0.1 1.7 2 0 0 2 2 2 1 Fibronectin type III domain ig PF00047.25 CDJ98076.1 - 8e-12 45.2 0.0 1.6e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CDJ98076.1 - 1.7e-09 37.9 0.0 3.5e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 CDJ98076.1 - 1.3e-08 34.9 0.2 2.7e-06 27.5 0.1 2.6 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_6 PF18452.1 CDJ98076.1 - 0.00013 21.5 0.0 0.00023 20.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Herpes_gE PF02480.16 CDJ98076.1 - 0.00035 19.4 0.0 0.00066 18.5 0.0 1.4 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E Pur_ac_phosph_N PF16656.5 CDJ98076.1 - 0.014 16.0 0.8 0.21 12.2 0.1 2.7 2 1 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain C2-set_2 PF08205.12 CDJ98076.1 - 0.031 14.3 0.1 0.078 13.1 0.0 1.7 1 1 0 1 1 1 0 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 CDJ98076.1 - 0.045 14.1 0.0 0.35 11.3 0.0 2.4 2 1 1 3 3 3 0 Immunoglobulin C1-set domain PH_RBD PF12068.8 CDJ98077.1 - 8e-11 41.7 0.0 1.2e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Rab-binding domain (RBD) DUF3388 PF11868.8 CDJ98078.1 - 0.042 13.2 0.1 0.057 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3388) GWT1 PF06423.12 CDJ98080.1 - 0.0029 17.8 1.7 0.0057 16.8 1.2 1.8 2 0 0 2 2 2 1 GWT1 Frag1 PF10277.9 CDJ98080.1 - 0.11 12.1 21.7 0.38 10.3 21.7 1.9 1 1 0 1 1 1 0 Frag1/DRAM/Sfk1 family TMPIT PF07851.13 CDJ98081.1 - 1.3e-82 277.6 12.5 1.7e-82 277.3 12.5 1.0 1 0 0 1 1 1 1 TMPIT-like protein DUF5305 PF17231.2 CDJ98081.1 - 0.24 10.8 0.0 0.38 10.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Popeye PF04831.13 CDJ98081.1 - 1.4 9.1 6.5 5 7.3 1.8 2.5 2 0 0 2 2 2 0 Popeye protein conserved region Homeodomain PF00046.29 CDJ98082.1 - 6.8e-21 73.9 6.6 1.2e-20 73.1 6.6 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ98082.1 - 0.33 10.9 3.6 2.2 8.3 0.5 2.5 1 1 1 2 2 2 0 Homeobox KN domain Forkhead PF00250.18 CDJ98083.1 - 9.1e-33 112.4 0.1 7e-32 109.5 0.0 2.4 2 0 0 2 2 2 1 Forkhead domain 2OG-FeII_Oxy_2 PF13532.6 CDJ98083.1 - 2.5e-07 31.1 0.0 2.7e-06 27.7 0.0 2.5 2 1 1 3 3 3 1 2OG-Fe(II) oxygenase superfamily Pinin_SDK_memA PF04696.13 CDJ98083.1 - 0.0034 17.4 0.9 0.0074 16.3 0.0 1.9 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region 2OG-FeII_Oxy PF03171.20 CDJ98083.1 - 0.043 14.3 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily FAST_1 PF06743.15 CDJ98084.1 - 2.9e-05 23.9 0.0 0.14 12.1 0.0 4.0 4 0 0 4 4 4 2 FAST kinase-like protein, subdomain 1 RNase_PH PF01138.21 CDJ98085.1 - 2.9e-20 73.1 0.3 6.7e-20 71.9 0.1 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CDJ98085.1 - 6.8e-07 29.2 0.0 1.3e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 zf-Tim10_DDP PF02953.15 CDJ98086.1 - 4.5e-15 55.0 1.9 6.3e-15 54.6 1.9 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Furin-like PF00757.20 CDJ98086.1 - 0.0072 16.2 1.7 0.0084 16.0 1.7 1.1 1 0 0 1 1 1 1 Furin-like cysteine rich region DUF1077 PF06417.12 CDJ98087.1 - 2.1e-47 160.0 2.8 4.7e-47 158.8 2.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) LCM PF04072.14 CDJ98087.1 - 5.8e-30 104.6 0.0 1.4e-29 103.4 0.0 1.6 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Biotin_carb_N PF00289.22 CDJ98088.1 - 4.6e-25 88.3 0.6 5.2e-25 88.1 0.6 1.0 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 CDJ98089.1 - 3.5e-15 55.6 0.9 5.2e-15 55.0 0.9 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CDJ98089.1 - 1.9e-08 34.0 0.6 3.4e-05 23.6 0.1 2.3 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 CDJ98089.1 - 0.00049 19.4 0.1 0.045 13.0 0.0 2.1 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 CDJ98089.1 - 0.00099 19.8 0.1 2 9.2 0.0 2.3 2 0 0 2 2 2 2 HlyD family secretion protein NQRA PF05896.11 CDJ98089.1 - 0.0017 17.8 0.1 0.0018 17.7 0.1 1.1 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RnfC_N PF13375.6 CDJ98089.1 - 0.027 14.4 0.1 0.042 13.8 0.1 1.4 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.9 CDJ98089.1 - 0.081 12.9 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) SPARC_Ca_bdg PF10591.9 CDJ98090.1 - 5.5e-24 84.7 0.1 6.1e-24 84.5 0.1 1.0 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_6 PF13405.6 CDJ98090.1 - 0.00027 20.6 0.0 0.005 16.7 0.0 2.3 2 1 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CDJ98090.1 - 0.00034 19.9 0.0 0.0018 17.7 0.0 2.1 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 CDJ98090.1 - 0.00075 18.9 0.2 0.0021 17.5 0.0 1.8 2 0 0 2 2 2 1 EF hand Patatin PF01734.22 CDJ98091.1 - 2.3e-25 90.0 0.0 1e-24 87.9 0.0 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase Alpha-amylase PF00128.24 CDJ98092.1 - 5.7e-36 124.7 0.0 1.5e-35 123.4 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain SLC3A2_N PF16028.5 CDJ98092.1 - 1.1e-23 82.6 0.8 1.9e-23 81.8 0.8 1.4 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus Photo_RC PF00124.19 CDJ98092.1 - 0.011 14.9 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre protein Glyco_hydro_42C PF08533.10 CDJ98092.1 - 0.013 15.2 0.0 1.9 8.3 0.0 2.5 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain DnaT PF17948.1 CDJ98092.1 - 0.07 12.8 1.9 0.58 9.9 0.0 2.8 3 0 0 3 3 3 0 DnaT DNA-binding domain Glyco_hydro_114 PF03537.13 CDJ98092.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 Asp PF00026.23 CDJ98094.1 - 4.9e-68 229.9 0.0 5.8e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ98094.1 - 2.6e-08 34.3 1.3 9.3e-07 29.3 1.2 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ98094.1 - 1.6e-06 28.0 0.0 4.5e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Pkinase PF00069.25 CDJ98095.1 - 0.04 13.3 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ98095.1 - 0.063 12.6 0.2 0.066 12.5 0.2 1.0 1 0 0 1 1 1 0 Protein tyrosine kinase PP28 PF10252.9 CDJ98095.1 - 0.16 12.4 0.0 0.21 12.1 0.0 1.2 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 ISG65-75 PF11727.8 CDJ98096.1 - 0.034 13.4 2.9 0.049 12.9 2.9 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF2884 PF11101.8 CDJ98096.1 - 0.054 13.0 0.4 0.087 12.3 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) FliT PF05400.13 CDJ98096.1 - 0.61 10.9 5.7 2.4 9.0 5.7 1.9 1 1 0 1 1 1 0 Flagellar protein FliT RVT_1 PF00078.27 CDJ98097.1 - 7.1e-16 58.4 0.0 1e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 CDJ98098.1 - 2e-35 122.4 0.5 2.5e-35 122.1 0.5 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ98098.1 - 1.2e-25 90.3 0.1 1.5e-25 90.0 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ98098.1 - 0.00088 18.2 0.1 0.0015 17.4 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 CDJ98098.1 - 0.0066 16.1 0.0 0.008 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CDJ98098.1 - 0.009 15.0 0.3 0.011 14.7 0.3 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CDJ98098.1 - 0.015 14.7 0.1 0.019 14.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDJ98098.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RVT_1 PF00078.27 CDJ98099.1 - 7.4e-16 58.3 0.0 1.4e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CDJ98100.1 - 5e-05 23.8 0.0 7.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ98100.1 - 0.12 13.1 0.1 0.45 11.2 0.1 1.9 1 1 0 1 1 1 0 Aspartyl protease PAN_1 PF00024.26 CDJ98102.1 - 1.4e-14 53.8 5.2 3.9e-10 39.6 2.5 2.4 2 0 0 2 2 2 2 PAN domain DUF1759 PF03564.15 CDJ98103.1 - 2.2e-29 102.3 2.8 3.8e-29 101.5 2.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Retrotran_gag_2 PF14223.6 CDJ98103.1 - 0.002 17.8 0.6 0.0063 16.2 0.6 1.9 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type ArsR PF09824.9 CDJ98103.1 - 0.031 13.9 0.1 0.07 12.7 0.1 1.6 1 0 0 1 1 1 0 ArsR transcriptional regulator ABC_tran_CTD PF16326.5 CDJ98103.1 - 2.7 8.3 5.8 26 5.2 0.8 3.0 3 1 1 4 4 4 0 ABC transporter C-terminal domain Helicase_C PF00271.31 CDJ98106.1 - 2.5e-10 40.7 0.0 3.9e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CDJ98106.1 - 0.00034 19.9 0.0 0.00039 19.7 0.0 1.1 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Cation_efflux PF01545.21 CDJ98107.1 - 1.1e-21 77.5 7.7 1.4e-21 77.2 7.7 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 CDJ98107.1 - 7e-11 42.1 1.2 1.3e-10 41.3 1.2 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Voltage_CLC PF00654.20 CDJ98107.1 - 0.034 13.4 1.4 0.071 12.3 1.3 1.5 1 1 0 1 1 1 0 Voltage gated chloride channel MARVEL PF01284.23 CDJ98108.1 - 0.063 13.3 0.0 0.068 13.2 0.0 1.1 1 0 0 1 1 1 0 Membrane-associating domain RVT_1 PF00078.27 CDJ98109.1 - 3.6e-29 101.9 0.0 4.9e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2828 PF11443.8 CDJ98110.1 - 1.5 6.8 18.1 1.8 6.6 18.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) FGF-BP1 PF06473.12 CDJ98110.1 - 1.9 8.3 22.0 2.1 8.1 22.0 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Rtf2 PF04641.12 CDJ98110.1 - 3.1 7.1 25.2 3.2 7.0 25.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger SpoIIP PF07454.11 CDJ98110.1 - 4 6.8 17.2 5 6.5 17.2 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CDC45 PF02724.14 CDJ98110.1 - 4.9 5.3 26.9 4.9 5.3 26.9 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 CDJ98110.1 - 6.7 6.4 25.8 7.2 6.4 25.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 CDJ98110.1 - 7.3 7.0 20.2 9.9 6.6 20.2 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 CDJ98110.1 - 7.3 5.2 18.1 7.6 5.2 18.1 1.0 1 0 0 1 1 1 0 Presenilin RP-C_C PF11800.8 CDJ98110.1 - 9.9 6.2 11.7 11 6.1 11.7 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region MGAT2 PF05060.14 CDJ98111.1 - 1.2e-138 461.9 2.7 1.6e-138 461.5 2.7 1.1 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) TatD_DNase PF01026.21 CDJ98111.1 - 0.085 12.2 0.0 0.23 10.8 0.0 1.7 1 0 0 1 1 1 0 TatD related DNase Homeodomain PF00046.29 CDJ98112.1 - 5.3e-20 71.0 0.6 8.8e-20 70.3 0.6 1.3 1 0 0 1 1 1 1 Homeodomain LIM PF00412.22 CDJ98112.1 - 6e-09 36.0 3.6 6.7e-08 32.6 1.5 2.4 2 0 0 2 2 2 1 LIM domain Homeobox_KN PF05920.11 CDJ98112.1 - 0.00019 21.3 0.0 0.00048 20.0 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain MerR PF00376.23 CDJ98112.1 - 0.00096 18.9 0.3 0.0023 17.7 0.3 1.7 1 0 0 1 1 1 1 MerR family regulatory protein DiS_P_DiS PF06750.13 CDJ98112.1 - 0.019 15.1 2.7 2.1 8.5 0.1 2.9 2 1 1 3 3 3 0 Bacterial Peptidase A24 N-terminal domain MerR_1 PF13411.6 CDJ98112.1 - 0.027 14.6 0.1 0.5 10.5 0.0 2.4 2 0 0 2 2 2 0 MerR HTH family regulatory protein SBP56 PF05694.11 CDJ98113.1 - 3.5e-48 164.5 0.0 3.1e-33 115.3 0.0 3.0 2 1 1 3 3 3 3 56kDa selenium binding protein (SBP56) Kelch_1 PF01344.25 CDJ98114.1 - 1.9e-29 100.9 0.8 1e-14 53.8 0.0 3.5 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 CDJ98114.1 - 2.7e-21 75.1 0.6 1e-08 35.2 0.0 3.1 2 1 1 3 3 3 3 Kelch motif Kelch_2 PF07646.15 CDJ98114.1 - 1.7e-09 37.2 0.2 0.0024 17.8 0.0 2.9 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CDJ98114.1 - 1.9e-07 31.0 0.2 0.0084 16.1 0.0 2.8 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ98114.1 - 9.1e-06 25.8 0.8 0.093 13.0 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ98114.1 - 0.021 14.8 0.0 4.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Kelch motif Pex19 PF04614.12 CDJ98115.1 - 3.4e-40 138.3 8.1 3.4e-40 138.3 8.1 1.3 1 1 0 1 1 1 1 Pex19 protein family DUF1308 PF07000.11 CDJ98115.1 - 0.013 15.4 0.3 0.02 14.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) Phage_TAC_12 PF12363.8 CDJ98115.1 - 0.014 15.8 0.5 0.057 13.8 0.1 2.0 1 1 1 2 2 2 0 Phage tail assembly chaperone protein, TAC Ku_PK_bind PF08785.11 CDJ98115.1 - 0.014 15.5 0.2 0.027 14.6 0.2 1.5 1 0 0 1 1 1 0 Ku C terminal domain like DUF3450 PF11932.8 CDJ98115.1 - 0.05 12.9 5.4 0.08 12.2 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) EcKinase PF02958.20 CDJ98115.1 - 0.058 12.7 0.9 0.097 12.0 0.9 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase FliE PF02049.18 CDJ98115.1 - 0.17 12.1 10.1 0.6 10.3 8.7 2.2 1 1 1 2 2 2 0 Flagellar hook-basal body complex protein FliE Lant_dehydr_C PF14028.6 CDJ98115.1 - 0.18 11.3 1.6 14 5.1 1.7 2.1 1 1 0 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term DUF2937 PF11157.8 CDJ98115.1 - 0.48 10.1 5.8 0.81 9.4 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) DUF4200 PF13863.6 CDJ98115.1 - 0.54 10.7 7.2 0.14 12.5 3.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) TnpV PF14198.6 CDJ98115.1 - 2 8.5 7.1 4.9 7.2 0.5 2.7 2 1 1 3 3 3 0 Transposon-encoded protein TnpV Flavi_DEAD PF07652.14 CDJ98117.1 - 1.5e-15 57.5 1.7 2.5e-15 56.7 1.7 1.3 1 0 0 1 1 1 1 Flavivirus DEAD domain DEAD PF00270.29 CDJ98117.1 - 4.9e-08 32.9 0.2 7.3e-08 32.4 0.2 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CDJ98117.1 - 0.0011 19.4 0.3 0.0018 18.6 0.3 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CDJ98117.1 - 0.0015 18.6 0.5 0.0062 16.5 0.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 CDJ98117.1 - 0.0042 17.0 0.1 0.0063 16.4 0.1 1.2 1 0 0 1 1 1 1 Helicase Neur_chan_memb PF02932.16 CDJ98118.1 - 1.6e-28 100.4 5.2 3.9e-27 95.8 3.9 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CDJ98118.1 - 2.4e-09 37.0 0.9 1.7e-05 24.4 0.2 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain UNC-50 PF05216.13 CDJ98119.1 - 3.5e-82 275.3 21.3 4.1e-82 275.0 21.3 1.0 1 0 0 1 1 1 1 UNC-50 family FtsX PF02687.21 CDJ98119.1 - 1.9 9.0 18.5 36 4.9 13.7 3.0 1 1 1 2 2 2 0 FtsX-like permease family DUF2205 PF10224.9 CDJ98120.1 - 6.3e-26 90.2 0.7 8.1e-26 89.8 0.7 1.1 1 0 0 1 1 1 1 Short coiled-coil protein CENP-H PF05837.12 CDJ98120.1 - 0.0023 18.3 0.6 0.0028 18.0 0.6 1.1 1 0 0 1 1 1 1 Centromere protein H (CENP-H) FliT PF05400.13 CDJ98120.1 - 0.0067 17.2 0.1 0.0096 16.7 0.1 1.2 1 0 0 1 1 1 1 Flagellar protein FliT KASH_CCD PF14662.6 CDJ98120.1 - 0.009 15.9 0.4 0.012 15.5 0.4 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH YabA PF06156.13 CDJ98120.1 - 0.012 16.3 0.9 0.015 15.9 0.9 1.1 1 0 0 1 1 1 0 Initiation control protein YabA Myosin_tail_1 PF01576.19 CDJ98120.1 - 0.013 13.4 0.7 0.016 13.1 0.7 1.0 1 0 0 1 1 1 0 Myosin tail Sas10_Utp3 PF04000.15 CDJ98120.1 - 0.014 16.0 0.5 0.02 15.5 0.5 1.2 1 0 0 1 1 1 0 Sas10/Utp3/C1D family UPF0242 PF06785.11 CDJ98120.1 - 0.016 15.3 0.1 0.017 15.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cep57_CLD_2 PF14197.6 CDJ98120.1 - 0.019 15.1 0.9 0.026 14.6 0.9 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 TACC_C PF05010.14 CDJ98120.1 - 0.022 14.6 0.0 0.028 14.2 0.0 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FlaC_arch PF05377.11 CDJ98120.1 - 0.029 14.8 1.4 0.052 13.9 1.4 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) ZapB PF06005.12 CDJ98120.1 - 0.051 14.0 1.2 0.065 13.7 1.2 1.2 1 0 0 1 1 1 0 Cell division protein ZapB JIP_LZII PF16471.5 CDJ98120.1 - 0.078 13.2 0.7 0.12 12.5 0.7 1.4 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II HALZ PF02183.18 CDJ98120.1 - 0.14 12.4 5.2 1.9 8.8 1.9 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 CDJ98120.1 - 0.18 11.9 1.2 0.46 10.6 0.9 1.5 1 1 1 2 2 2 0 bZIP transcription factor DUF5641 PF18701.1 CDJ98122.1 - 2e-18 66.3 0.1 4.5e-18 65.2 0.1 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5641) Peptidase_A17 PF05380.13 CDJ98122.1 - 5e-13 49.4 0.3 1e-12 48.4 0.3 1.5 1 0 0 1 1 1 1 Pao retrotransposon peptidase Integrase_H2C2 PF17921.1 CDJ98122.1 - 1.2e-12 47.7 2.9 2.7e-12 46.6 2.9 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDJ98122.1 - 3.1e-11 43.5 0.0 6.9e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDJ98122.1 - 0.00015 21.5 0.0 0.00042 20.0 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CDJ98122.1 - 0.0095 16.1 3.6 0.028 14.6 3.6 1.9 1 0 0 1 1 1 1 H2C2 zinc finger DUF1664 PF07889.12 CDJ98123.1 - 0.023 14.7 3.6 0.033 14.2 1.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CorA PF01544.18 CDJ98123.1 - 0.1 11.9 4.0 0.21 10.9 4.0 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein zf-Sec23_Sec24 PF04810.15 CDJ98123.1 - 8.3 6.6 8.0 4.5 7.4 0.1 3.1 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger DFRP_C PF16543.5 CDJ98124.1 - 0.025 15.1 0.3 0.048 14.2 0.3 1.4 1 0 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 RT_RNaseH PF17917.1 CDJ98125.1 - 3.9e-34 117.1 0.0 7.6e-34 116.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ98125.1 - 4.2e-33 113.4 0.0 2.8e-32 110.7 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ98125.1 - 1.5e-17 63.9 0.0 7e-17 61.7 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ98125.1 - 1.6e-15 56.9 0.1 4.1e-15 55.6 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 CDJ98125.1 - 3e-10 40.0 0.0 5.5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 CDJ98125.1 - 0.00025 21.2 0.1 0.015 15.5 0.0 3.1 3 0 0 3 3 3 1 H2C2 zinc finger rve_3 PF13683.6 CDJ98125.1 - 0.011 15.5 0.1 0.03 14.1 0.0 1.8 2 0 0 2 2 2 0 Integrase core domain Peptidase_A17 PF05380.13 CDJ98125.1 - 0.015 15.3 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Pao retrotransposon peptidase gag-asp_proteas PF13975.6 CDJ98126.1 - 5.2e-05 23.7 0.0 0.00014 22.3 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ98126.1 - 0.052 13.9 0.1 0.28 11.5 0.0 2.1 2 0 0 2 2 2 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ98126.1 - 0.061 14.0 0.0 0.18 12.5 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease Methyltransf_21 PF05050.12 CDJ98127.1 - 1.4e-12 48.0 0.0 1.8e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_21 PF05050.12 CDJ98128.1 - 1.1e-13 51.6 0.0 1.5e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain P-mevalo_kinase PF04275.14 CDJ98128.1 - 0.084 12.8 0.2 0.2 11.6 0.2 1.6 1 0 0 1 1 1 0 Phosphomevalonate kinase SCVP PF17619.2 CDJ98129.1 - 6.3e-40 135.9 6.5 5.3e-20 72.1 0.3 2.2 2 0 0 2 2 2 2 Secreted clade V proteins DUF866 PF05907.13 CDJ98129.1 - 0.022 14.7 0.2 7.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF866) Methyltransf_21 PF05050.12 CDJ98130.1 - 3.7e-12 46.6 0.0 5.9e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain SCVP PF17619.2 CDJ98131.1 - 3.8e-54 181.5 9.1 7.7e-23 81.2 2.0 3.2 3 0 0 3 3 3 3 Secreted clade V proteins DUF866 PF05907.13 CDJ98131.1 - 0.0045 16.9 0.1 0.92 9.4 0.1 2.9 3 0 0 3 3 3 2 Eukaryotic protein of unknown function (DUF866) SCVP PF17619.2 CDJ98132.1 - 2.2e-28 98.9 4.2 3.8e-19 69.3 0.3 3.2 2 1 1 3 3 3 3 Secreted clade V proteins ATP-synt PF00231.19 CDJ98134.1 - 3.1e-80 269.9 6.3 3.5e-80 269.7 6.3 1.0 1 0 0 1 1 1 1 ATP synthase T2SSF PF00482.23 CDJ98135.1 - 0.067 13.2 2.5 0.11 12.4 0.2 2.5 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F Tropomyosin PF00261.20 CDJ98135.1 - 0.68 9.3 19.0 0.039 13.3 12.3 2.0 2 0 0 2 2 2 0 Tropomyosin DivIC PF04977.15 CDJ98135.1 - 2.5 7.9 5.6 15 5.4 0.1 3.0 2 1 0 2 2 2 0 Septum formation initiator V_ATPase_I PF01496.19 CDJ98135.1 - 4.3 5.1 6.6 2.2 6.1 4.6 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 CDJ98135.1 - 6.9 5.7 10.9 2.9 6.9 8.3 1.6 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CSD PF00313.22 CDJ98136.1 - 6.2e-23 80.4 0.0 1e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain Oxidored_q6 PF01058.22 CDJ98137.1 - 0.86 9.4 2.4 1.1 9.0 2.4 1.5 1 1 0 1 1 1 0 NADH ubiquinone oxidoreductase, 20 Kd subunit ubiquitin PF00240.23 CDJ98138.1 - 0.00038 20.2 0.0 0.00094 18.9 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin family Ubiquitin_4 PF18036.1 CDJ98138.1 - 0.044 13.8 0.0 0.17 12.0 0.0 1.9 2 1 0 2 2 2 0 Ubiquitin-like domain zf-AN1 PF01428.16 CDJ98139.1 - 0.00025 21.2 10.6 0.00041 20.4 10.6 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger zf-RING_5 PF14634.6 CDJ98139.1 - 2 8.4 9.0 4 7.5 9.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DUF236 PF03057.14 CDJ98140.1 - 1.3e-108 354.5 38.6 1.4e-15 57.0 0.4 7.4 7 0 0 7 7 7 7 DUF236 repeat Dsh_C PF12316.8 CDJ98140.1 - 0.00051 20.5 0.2 0.00089 19.7 0.2 1.3 1 0 0 1 1 1 1 Segment polarity protein dishevelled (Dsh) C terminal RsdA_SigD_bd PF16751.5 CDJ98140.1 - 0.15 12.3 0.0 1.1e+02 3.2 0.0 4.7 6 0 0 6 6 6 0 Anti-sigma-D factor RsdA to sigma factor binding region Peptidase_C58 PF03543.14 CDJ98140.1 - 0.22 11.2 3.7 2.1e+02 1.5 0.0 5.3 7 0 0 7 7 7 0 Yersinia/Haemophilus virulence surface antigen JLPA PF16668.5 CDJ98140.1 - 0.27 10.2 3.2 60 2.5 0.0 4.8 7 0 0 7 7 7 0 Adhesin from Campylobacter Rrn6 PF10214.9 CDJ98140.1 - 1.6 7.1 4.3 2.2 6.7 4.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DmsC PF04976.12 CDJ98141.1 - 0.017 14.6 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 DMSO reductase anchor subunit (DmsC) DUF5641 PF18701.1 CDJ98142.1 - 5.6e-19 68.1 0.0 1e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5641) rve PF00665.26 CDJ98142.1 - 2.2e-07 31.1 0.0 6.5e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 CDJ98142.1 - 0.0011 18.6 0.1 0.0032 17.2 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain adh_short PF00106.25 CDJ98143.1 - 4e-30 104.7 0.1 6.6e-30 104.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ98143.1 - 4.8e-21 75.4 0.1 7.2e-21 74.8 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 CDJ98143.1 - 1.1e-06 28.7 0.1 2.3e-06 27.7 0.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 CDJ98143.1 - 3.1e-06 27.2 0.1 5e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 KR domain ATP-synt_F PF01990.17 CDJ98143.1 - 0.00058 20.1 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit 3Beta_HSD PF01073.19 CDJ98143.1 - 0.0015 17.6 0.2 0.002 17.2 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 CDJ98143.1 - 0.0021 17.7 0.1 0.0033 17.0 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 CDJ98143.1 - 0.0022 17.5 0.2 0.0029 17.1 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 CDJ98143.1 - 0.028 14.7 0.2 0.062 13.6 0.1 1.6 1 1 0 1 1 1 0 TrkA-N domain NAD_binding_4 PF07993.12 CDJ98143.1 - 0.047 12.8 0.1 0.13 11.4 0.1 1.7 2 0 0 2 2 2 0 Male sterility protein Fimbrial PF00419.20 CDJ98143.1 - 0.099 12.9 0.3 0.17 12.1 0.3 1.3 1 0 0 1 1 1 0 Fimbrial protein Exo_endo_phos_2 PF14529.6 CDJ98144.1 - 1.6e-05 24.7 0.2 6.5e-05 22.8 0.0 2.1 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDJ98144.1 - 0.005 16.4 0.0 0.0071 15.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Moulting_cycle PF04870.16 CDJ98145.1 - 2.3e-82 277.1 13.1 3.3e-81 273.3 13.1 2.2 1 1 0 1 1 1 1 Moulting cycle FTCD_C PF04961.12 CDJ98145.1 - 0.093 12.5 7.4 0.22 11.3 4.1 2.5 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase UPF0253 PF06786.12 CDJ98145.1 - 0.16 12.2 0.0 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0253) Syntaxin_2 PF14523.6 CDJ98145.1 - 3.8 7.9 8.1 0.39 11.1 2.0 2.6 3 1 1 4 4 4 0 Syntaxin-like protein DIX PF00778.17 CDJ98146.1 - 9.6e-23 79.8 0.0 1.8e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 DIX domain PDZ PF00595.24 CDJ98146.1 - 1.3e-18 67.1 0.7 3.2e-18 65.9 0.7 1.7 1 0 0 1 1 1 1 PDZ domain DEP PF00610.21 CDJ98146.1 - 3.3e-13 49.5 0.0 7.9e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Dishevelled PF02377.15 CDJ98146.1 - 3.2e-12 47.2 14.6 8.6e-12 45.8 14.6 1.8 1 0 0 1 1 1 1 Dishevelled specific domain PDZ_2 PF13180.6 CDJ98146.1 - 0.0037 17.6 0.2 0.0081 16.5 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDJ98146.1 - 0.021 14.7 0.1 0.05 13.5 0.1 1.7 1 0 0 1 1 1 0 PDZ domain 7TM_GPCR_Srab PF10292.9 CDJ98147.1 - 1.4e-28 99.8 22.3 1.9e-28 99.3 22.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor Sre PF03125.18 CDJ98147.1 - 1.4e-15 57.4 20.8 6.8e-15 55.1 20.8 2.1 1 1 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor 7tm_1 PF00001.21 CDJ98147.1 - 8.1e-05 22.1 16.8 8.1e-05 22.1 16.8 2.2 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF5305 PF17231.2 CDJ98147.1 - 0.21 11.0 2.7 1.3 8.3 0.1 3.0 2 2 2 4 4 4 0 Family of unknown function (DUF5305) NPV_P10 PF05531.12 CDJ98148.1 - 0.063 13.8 3.5 3.4 8.2 0.9 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein RP-C_C PF11800.8 CDJ98148.1 - 0.16 12.1 5.4 0.3 11.2 5.4 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region HsbA PF12296.8 CDJ98148.1 - 0.21 12.0 5.6 0.083 13.3 1.4 2.1 2 0 0 2 2 2 0 Hydrophobic surface binding protein A SURF2 PF05477.11 CDJ98148.1 - 0.75 9.5 12.6 1.2 8.7 12.6 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Myelin_PLP PF01275.19 CDJ98149.1 - 2.5e-34 119.2 17.5 3.3e-34 118.8 17.5 1.1 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) DUF1345 PF07077.11 CDJ98149.1 - 0.0019 18.0 3.6 0.004 16.9 3.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1345) DUF5408 PF17402.2 CDJ98149.1 - 0.072 13.0 0.0 0.072 13.0 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5408) DUF373 PF04123.13 CDJ98149.1 - 2 7.7 6.1 12 5.2 5.8 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF373) DB PF01682.19 CDJ98150.1 - 1.2e-20 73.6 11.3 2e-20 72.9 11.3 1.4 1 0 0 1 1 1 1 DB module DUF1489 PF07370.11 CDJ98150.1 - 1.7 8.3 7.3 3.7 7.3 7.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1489) Band_7 PF01145.25 CDJ98151.1 - 8.8e-24 84.5 1.3 1.3e-23 83.9 1.3 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.8 CDJ98151.1 - 0.068 13.3 0.4 0.13 12.4 0.4 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 DUF1191 PF06697.12 CDJ98151.1 - 0.089 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Rft-1 PF04506.13 CDJ98153.1 - 3.6e-99 332.9 36.9 4.3e-99 332.6 36.9 1.0 1 0 0 1 1 1 1 Rft protein CytochromB561_N PF09786.9 CDJ98153.1 - 0.28 10.2 3.9 0.1 11.6 0.5 1.9 2 0 0 2 2 2 0 Cytochrome B561, N terminal 7tm_3 PF00003.22 CDJ98154.1 - 6.2e-55 186.5 21.6 1.1e-54 185.7 21.6 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 CDJ98154.1 - 4.5e-42 144.4 0.0 6.7e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 CDJ98154.1 - 8.6e-07 28.9 0.0 8.7e-06 25.6 0.0 2.0 1 1 0 1 1 1 1 Periplasmic binding protein Keratin_assoc PF09775.9 CDJ98154.1 - 0.009 15.7 0.1 0.026 14.2 0.1 1.8 1 0 0 1 1 1 1 Keratinocyte-associated protein 2 Cation_ATPase_C PF00689.21 CDJ98154.1 - 0.27 10.9 15.6 0.038 13.7 1.5 2.6 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus Sigma_reg_N PF13800.6 CDJ98154.1 - 0.58 10.5 3.0 1.2 9.5 1.1 2.4 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Baculo_11_kDa PF06143.11 CDJ98154.1 - 2 8.1 6.4 0.53 9.9 1.2 2.6 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF236 PF03057.14 CDJ98156.1 - 4.5e-60 199.2 32.3 9.8e-16 57.4 2.3 4.4 4 0 0 4 4 4 4 DUF236 repeat Pro-rich PF15240.6 CDJ98156.1 - 0.017 15.4 18.7 0.023 15.0 18.7 1.3 1 0 0 1 1 1 0 Proline-rich Tetradecapep PF08187.11 CDJ98156.1 - 5.2 7.3 6.0 88 3.5 0.3 3.6 1 1 1 2 2 2 0 Myoactive tetradecapeptides family Collagen PF01391.18 CDJ98157.1 - 7.1e-15 54.5 133.3 2.2e-07 30.5 37.5 4.8 2 1 2 4 4 4 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ98157.1 - 1.1e-13 51.0 0.7 1.4e-13 50.7 0.7 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain DUF4266 PF14086.6 CDJ98157.1 - 0.077 14.0 0.2 0.077 14.0 0.2 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4266) Sugar_tr PF00083.24 CDJ98159.1 - 9.8e-63 212.6 20.5 1.2e-62 212.3 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ98159.1 - 6e-16 58.3 30.2 5.2e-10 38.8 6.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AGOG PF09171.10 CDJ98159.1 - 0.2 10.9 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 N-glycosylase/DNA lyase DDDD PF10161.9 CDJ98159.1 - 1.9 8.3 3.3 60 3.5 0.0 3.3 3 0 0 3 3 3 0 Putative mitochondrial precursor protein Aa_trans PF01490.18 CDJ98160.1 - 2e-09 36.7 1.5 2.2e-09 36.6 1.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 CDJ98161.1 - 3.3e-59 200.7 15.3 3.9e-59 200.4 15.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CDJ98161.1 - 0.00014 21.0 15.8 0.00019 20.6 15.8 1.2 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.6 CDJ98161.1 - 0.81 8.5 36.5 1.1 8.1 23.2 2.4 2 1 0 2 2 2 0 Amino acid permease BCHF PF07284.11 CDJ98161.1 - 1.6 8.7 7.8 1.1 9.3 5.5 1.9 1 1 1 2 2 2 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) LapA_dom PF06305.11 CDJ98162.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain PNP_UDP_1 PF01048.20 CDJ98163.1 - 2.8e-48 164.2 0.1 3.3e-48 164.0 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily EIIA-man PF03610.16 CDJ98164.1 - 0.03 14.6 0.3 0.058 13.6 0.1 1.7 1 1 0 1 1 1 0 PTS system fructose IIA component RACo_linker PF17650.1 CDJ98164.1 - 0.034 14.0 0.5 0.13 12.2 0.2 2.0 1 1 1 2 2 2 0 RACo linker region MAAL_N PF05034.13 CDJ98164.1 - 0.085 12.5 0.2 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase N-terminus PSK_trans_fac PF07704.11 CDJ98164.1 - 1.7 9.4 6.1 3.1 8.6 3.0 2.6 1 1 2 3 3 3 0 Rv0623-like transcription factor RRM_1 PF00076.22 CDJ98166.1 - 2.5e-08 33.6 0.0 5.3e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Stm1_N PF09598.10 CDJ98166.1 - 0.088 13.7 0.8 0.22 12.4 0.8 1.6 1 0 0 1 1 1 0 Stm1 zf_C2H2_ZHX PF18387.1 CDJ98166.1 - 0.1 12.3 1.3 3.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 CDJ98166.1 - 0.15 12.4 2.7 2.4 8.5 1.3 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CDJ98166.1 - 0.98 10.4 5.0 5.7 8.1 1.4 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3439 PF11921.8 CDJ98166.1 - 2 8.4 5.4 5.1 7.1 5.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ima1_N PF09779.9 CDJ98167.1 - 2e-28 99.9 6.8 4.1e-28 98.9 6.8 1.5 1 0 0 1 1 1 1 Ima1 N-terminal domain Colicin_V PF02674.16 CDJ98167.1 - 0.0069 16.4 1.3 0.016 15.2 1.3 1.5 1 0 0 1 1 1 1 Colicin V production protein CAP PF00188.26 CDJ98168.1 - 1.6e-17 64.5 5.7 2.1e-17 64.1 5.7 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CDJ98169.1 - 0.00013 22.8 0.7 0.00051 20.9 0.7 1.9 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Longin PF13774.6 CDJ98170.1 - 1.2e-22 79.7 0.6 2e-22 79.0 0.6 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 CDJ98170.1 - 2.2e-14 53.0 0.1 3.7e-14 52.3 0.1 1.4 1 0 0 1 1 1 1 Synaptobrevin DUF1771 PF08590.10 CDJ98170.1 - 0.076 13.4 1.1 1.2 9.5 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1771) Pyr_redox_2 PF07992.14 CDJ98171.1 - 1.6e-61 208.1 0.2 2.7e-61 207.4 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CDJ98171.1 - 2e-33 115.0 1.2 7.7e-33 113.0 0.9 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CDJ98171.1 - 7.3e-22 77.7 4.2 5.2e-19 68.6 0.2 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CDJ98171.1 - 9.2e-17 61.2 1.6 3.2e-16 59.5 1.6 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ98171.1 - 2.1e-05 23.4 1.5 0.18 10.5 0.3 2.9 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.7 CDJ98171.1 - 9.8e-05 21.9 0.1 0.00021 20.8 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 CDJ98171.1 - 0.00031 20.0 0.8 0.011 14.9 0.4 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 CDJ98171.1 - 0.0087 16.0 0.3 0.055 13.3 0.0 2.4 3 1 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 CDJ98171.1 - 0.01 16.1 0.3 0.01 16.1 0.3 2.6 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Spo12 PF05032.12 CDJ98171.1 - 0.034 14.0 0.3 0.1 12.5 0.3 1.8 1 0 0 1 1 1 0 Spo12 family AlaDh_PNT_C PF01262.21 CDJ98171.1 - 0.04 13.2 5.7 0.95 8.7 0.3 3.1 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 CDJ98171.1 - 0.058 12.5 1.0 0.19 10.8 0.9 1.9 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 CDJ98171.1 - 0.073 12.6 10.8 0.85 9.1 0.1 2.9 3 1 1 4 4 4 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CDJ98171.1 - 0.94 8.7 6.4 3.5 6.8 0.4 3.2 4 1 1 5 5 5 0 FAD binding domain Peptidase_A17 PF05380.13 CDJ98173.1 - 2.9e-37 128.2 0.8 7.5e-37 126.8 0.8 1.8 1 0 0 1 1 1 1 Pao retrotransposon peptidase DUF1759 PF03564.15 CDJ98173.1 - 4e-27 95.0 2.2 4e-27 95.0 2.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DUF5641 PF18701.1 CDJ98173.1 - 1.1e-14 54.3 0.5 1.1e-14 54.3 0.5 3.1 3 0 0 3 3 3 1 Family of unknown function (DUF5641) Integrase_H2C2 PF17921.1 CDJ98173.1 - 5.6e-13 48.8 0.4 1.7e-12 47.2 0.4 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDJ98173.1 - 2.6e-08 34.1 0.0 1.8e-07 31.3 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain DUF1758 PF05585.12 CDJ98173.1 - 0.00032 20.5 0.0 0.00083 19.2 0.0 1.7 1 0 0 1 1 1 1 Putative peptidase (DUF1758) gag-asp_proteas PF13975.6 CDJ98173.1 - 0.0004 20.9 0.0 0.0016 19.0 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ98173.1 - 0.0012 19.4 0.0 0.003 18.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 CDJ98173.1 - 0.0025 17.4 0.5 0.018 14.6 0.0 2.6 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 CDJ98173.1 - 0.011 15.5 0.0 0.037 13.8 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain Ly49 PF08391.10 CDJ98173.1 - 0.03 14.7 1.4 13 6.2 0.0 3.3 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region zf-H2C2 PF09337.10 CDJ98173.1 - 0.037 14.2 0.6 0.11 12.7 0.6 1.9 1 0 0 1 1 1 0 H2C2 zinc finger Exog_C PF18026.1 CDJ98173.1 - 0.37 10.9 1.6 7.7 6.7 0.3 3.3 3 0 0 3 3 3 0 Endo/exonuclease (EXOG) C-terminal domain XhlA PF10779.9 CDJ98173.1 - 3.9 7.7 10.6 2.5 8.4 2.4 3.8 2 1 1 3 3 3 0 Haemolysin XhlA F-box PF00646.33 CDJ98174.1 - 0.00011 21.9 0.3 0.00028 20.7 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDJ98174.1 - 0.00077 19.3 0.2 0.0015 18.4 0.2 1.5 1 0 0 1 1 1 1 F-box-like PRANC PF09372.10 CDJ98174.1 - 0.0055 17.0 0.0 0.018 15.4 0.0 1.8 2 0 0 2 2 2 1 PRANC domain Pox_A14 PF05767.12 CDJ98175.1 - 0.0067 16.6 0.1 0.0067 16.6 0.1 1.2 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 Caldesmon PF02029.15 CDJ98177.1 - 0.04 12.7 0.1 0.052 12.3 0.1 1.1 1 0 0 1 1 1 0 Caldesmon APC_rep PF18797.1 CDJ98177.1 - 0.096 13.6 0.0 0.39 11.7 0.0 2.0 1 0 0 1 1 1 0 Adenomatous polyposis coli (APC) repeat DUF2973 PF11189.8 CDJ98178.1 - 0.59 10.3 3.1 1.9 8.6 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) DUF5437 PF17505.2 CDJ98179.1 - 2.2 8.3 6.0 0.91 9.6 1.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5437) Med15 PF09606.10 CDJ98180.1 - 3.3e-56 191.5 110.2 5.2e-33 114.8 106.5 3.5 1 1 1 3 3 3 2 ARC105 or Med15 subunit of Mediator complex non-fungal KIX_2 PF16987.5 CDJ98180.1 - 0.003 17.5 0.0 0.0081 16.1 0.0 1.8 1 0 0 1 1 1 1 KIX domain KIX PF02172.16 CDJ98180.1 - 0.48 10.7 2.7 0.48 10.7 0.3 2.3 2 1 0 2 2 2 0 KIX domain DEAD PF00270.29 CDJ98181.1 - 1.8e-51 174.4 0.0 5.6e-51 172.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ98181.1 - 4.8e-27 94.5 0.0 2.2e-26 92.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ98181.1 - 0.00031 20.8 0.2 0.0015 18.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cpn60_TCP1 PF00118.24 CDJ98182.1 - 8.8e-160 532.5 3.0 9.9e-160 532.4 3.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF4073 PF13285.6 CDJ98182.1 - 0.17 11.6 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4073) PID PF00640.23 CDJ98184.1 - 1.5e-21 76.9 0.0 2.9e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.6 CDJ98184.1 - 2.9e-05 24.0 0.1 4.8e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) NumbF PF06311.12 CDJ98184.1 - 0.00084 19.8 1.6 0.0012 19.3 0.2 2.1 2 0 0 2 2 2 1 NUMB domain PTB PF08416.13 CDJ98184.1 - 0.0039 17.3 0.0 0.006 16.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine-binding domain Neur_chan_LBD PF02931.23 CDJ98185.1 - 3.9e-36 124.5 2.0 4.7e-36 124.3 2.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain TTR-52 PF01060.23 CDJ98187.1 - 3e-28 98.3 0.0 4.4e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Transthyretin-like family Neur_chan_memb PF02932.16 CDJ98187.1 - 0.017 15.2 0.2 0.021 14.9 0.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TTR-52 PF01060.23 CDJ98188.1 - 4.8e-28 97.7 0.0 6e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Transthyretin-like family CAP PF00188.26 CDJ98189.1 - 1.6e-17 64.5 4.9 2.3e-17 64.0 4.9 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 CDJ98189.1 - 0.00031 21.0 4.4 0.0098 16.2 4.4 2.6 1 1 0 1 1 1 1 Ancylostoma-associated secreted protein related RVT_1 PF00078.27 CDJ98190.1 - 1.8e-18 66.9 0.1 2.4e-18 66.5 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5352 PF17303.2 CDJ98191.1 - 4e-54 183.0 0.5 4.8e-54 182.7 0.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5352) TSGP1 PF07771.11 CDJ98191.1 - 0.019 15.1 0.1 0.034 14.3 0.1 1.4 1 0 0 1 1 1 0 Tick salivary peptide group 1 ECH_2 PF16113.5 CDJ98191.1 - 0.085 12.3 0.0 0.096 12.2 0.0 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DUF5352 PF17303.2 CDJ98192.1 - 2.3e-54 183.7 0.4 2.8e-54 183.5 0.4 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5352) TSGP1 PF07771.11 CDJ98192.1 - 0.01 16.0 0.1 0.018 15.2 0.1 1.4 1 0 0 1 1 1 0 Tick salivary peptide group 1 ECH_2 PF16113.5 CDJ98192.1 - 0.053 13.0 0.0 0.06 12.8 0.0 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DUF5352 PF17303.2 CDJ98193.1 - 3e-53 180.1 0.4 3.2e-35 121.5 0.1 2.0 1 1 1 2 2 2 2 Family of unknown function (DUF5352) DUF5352 PF17303.2 CDJ98194.1 - 2.4e-49 167.4 0.3 1.2e-34 119.7 0.1 2.0 1 1 1 2 2 2 2 Family of unknown function (DUF5352) DUF5352 PF17303.2 CDJ98195.1 - 1.7e-47 161.4 0.2 2.2e-47 161.0 0.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5352) TSGP1 PF07771.11 CDJ98195.1 - 0.094 12.9 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Tick salivary peptide group 1 JHD PF17811.1 CDJ98196.1 - 3.1e-27 95.1 1.3 6.8e-27 94.0 1.3 1.6 1 0 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 CDJ98196.1 - 2.7e-08 34.2 0.3 5.1e-07 30.1 0.1 2.8 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CDJ98196.1 - 0.016 14.9 0.2 0.016 14.9 0.2 2.7 3 1 0 3 3 3 0 Cupin-like domain DUF1643 PF07799.12 CDJ98196.1 - 0.076 13.2 0.1 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1643) SNF2_N PF00176.23 CDJ98197.1 - 1.8e-67 227.6 0.0 2.8e-67 226.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ98197.1 - 5.2e-09 36.4 0.0 1.3e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 CDJ98197.1 - 5.6 7.1 13.6 0.82 9.7 8.2 2.6 2 0 0 2 2 2 0 RING-type zinc-finger Spond_N PF06468.13 CDJ98199.1 - 0.011 15.9 0.1 0.013 15.6 0.1 1.1 1 0 0 1 1 1 0 Spondin_N DUF418 PF04235.12 CDJ98199.1 - 0.049 13.6 0.1 0.09 12.7 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF418) Sigma_reg_N PF13800.6 CDJ98199.1 - 0.11 12.9 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal LIM PF00412.22 CDJ98200.1 - 1.2e-14 54.3 4.1 1.5e-14 53.9 4.1 1.1 1 0 0 1 1 1 1 LIM domain zf-DNA_Pol PF08996.10 CDJ98200.1 - 0.069 12.9 2.2 0.075 12.8 2.2 1.2 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger zf-SNAP50_C PF12251.8 CDJ98200.1 - 0.11 12.2 0.9 0.11 12.1 0.9 1.2 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal zf-TFIIB PF13453.6 CDJ98200.1 - 0.62 9.4 6.1 3.8 6.9 1.4 2.5 2 1 0 2 2 2 0 Transcription factor zinc-finger YdjO PF14169.6 CDJ98200.1 - 1.9 8.3 7.5 8 6.3 0.2 2.5 2 1 0 2 2 2 0 Cold-inducible protein YdjO ZU5 PF00791.20 CDJ98201.1 - 5.2e-20 71.6 0.0 1.4e-19 70.3 0.0 1.8 1 0 0 1 1 1 1 ZU5 domain Ig_3 PF13927.6 CDJ98201.1 - 3.2e-15 56.5 0.5 7.6e-15 55.3 0.0 1.9 2 0 0 2 2 1 1 Immunoglobulin domain Death PF00531.22 CDJ98201.1 - 7.5e-13 48.5 0.0 1.5e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Death domain I-set PF07679.16 CDJ98201.1 - 1.2e-12 47.7 0.0 2.4e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 CDJ98201.1 - 1.5e-12 47.6 0.0 4.6e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain UPA PF17217.3 CDJ98201.1 - 2.2e-11 43.8 0.0 3.8e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 UPA domain ig PF00047.25 CDJ98201.1 - 4.1e-10 39.7 0.0 8.9e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain TSP_1 PF00090.19 CDJ98201.1 - 2.4e-07 30.8 24.9 5e-07 29.8 6.9 4.0 3 0 0 3 3 3 2 Thrombospondin type 1 domain V-set PF07686.17 CDJ98201.1 - 1.4e-06 28.5 0.3 0.0042 17.2 0.1 3.5 3 1 0 3 3 3 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDJ98201.1 - 7.3e-05 22.8 0.0 0.0002 21.3 0.0 1.8 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 CDJ98201.1 - 0.048 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Receptor_2B4 PF11465.8 CDJ98201.1 - 0.064 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 Pneumo_att_G PF05539.11 CDJ98202.1 - 0.054 13.1 11.3 0.074 12.6 11.3 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF3037 PF11236.8 CDJ98202.1 - 0.27 11.7 3.3 28 5.2 1.4 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) HSBP1 PF06825.12 CDJ98202.1 - 1.1 9.1 7.6 1.8 8.5 1.0 3.0 3 1 0 3 3 3 0 Heat shock factor binding protein 1 Muted PF14942.6 CDJ98202.1 - 3.2 8.1 10.4 2.9 8.2 7.4 2.2 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein DUF1218 PF06749.12 CDJ98204.1 - 0.014 15.9 0.1 0.032 14.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1218) Carn_acyltransf PF00755.20 CDJ98205.1 - 2.8e-125 419.2 0.0 3.1e-125 419.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ABC_tran PF00005.27 CDJ98206.1 - 5.6e-07 30.2 0.0 9.8e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CDJ98206.1 - 0.00032 20.2 0.1 0.00043 19.8 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 CDJ98206.1 - 0.01 15.8 0.3 1.3 9.0 0.1 2.1 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) FKBP_N_2 PF18023.1 CDJ98206.1 - 0.094 12.8 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 BDBT FKBP like N-terminal Carn_acyltransf PF00755.20 CDJ98207.1 - 4.3e-09 35.6 0.3 5.5e-09 35.2 0.3 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ARID PF01388.21 CDJ98208.1 - 2.8e-18 66.4 0.0 6.8e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain RBB1NT PF08169.11 CDJ98208.1 - 3.2e-09 36.8 0.0 2.2e-08 34.1 0.0 2.5 1 0 0 1 1 1 1 RBB1NT (NUC162) domain Tudor-knot PF11717.8 CDJ98208.1 - 0.00035 20.4 0.1 0.00035 20.4 0.1 3.1 4 0 0 4 4 4 1 RNA binding activity-knot of a chromodomain Tudor_4 PF18358.1 CDJ98208.1 - 0.085 12.5 0.0 0.66 9.6 0.0 2.4 3 0 0 3 3 3 0 Histone methyltransferase Tudor domain F-box_5 PF18511.1 CDJ98208.1 - 0.12 12.0 1.0 0.31 10.6 1.0 1.7 1 0 0 1 1 1 0 F-box FAD-oxidase_C PF02913.19 CDJ98209.1 - 4.2e-65 219.9 0.2 7.1e-65 219.1 0.2 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CDJ98209.1 - 5.2e-30 104.0 0.1 1.1e-29 103.0 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain PIH1 PF08190.12 CDJ98209.1 - 4e-17 62.2 0.3 8.5e-17 61.1 0.3 1.4 1 0 0 1 1 1 1 PIH1 N-terminal domain Yip1 PF04893.17 CDJ98209.1 - 5.4e-10 39.3 8.6 8.7e-10 38.6 8.6 1.3 1 0 0 1 1 1 1 Yip1 domain Peptidase_C1 PF00112.23 CDJ98210.1 - 9.4e-67 225.3 9.6 1.7e-66 224.5 9.6 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ98210.1 - 0.0093 14.8 0.8 0.16 10.7 0.5 2.2 2 0 0 2 2 2 2 Peptidase C1-like family WD40 PF00400.32 CDJ98211.1 - 6.5e-37 124.9 18.2 4.2e-07 30.6 0.3 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ98211.1 - 1.2e-05 25.5 2.3 4.5 7.6 0.2 5.4 3 2 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CDJ98211.1 - 0.0033 16.2 0.3 0.05 12.3 0.1 2.7 2 1 0 2 2 2 1 Nup133 N terminal like Nup160 PF11715.8 CDJ98211.1 - 0.0039 15.9 3.7 0.19 10.4 0.6 2.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 PRP38 PF03371.15 CDJ98212.1 - 4.7e-61 205.7 0.7 6.2e-61 205.3 0.7 1.2 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 CDJ98212.1 - 9.7 6.9 116.4 1.8e+04 -23.8 116.4 2.8 1 1 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term SepSecS PF05889.13 CDJ98213.1 - 1.1e-142 475.3 0.0 1.3e-142 475.1 0.0 1.0 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 CDJ98213.1 - 0.0061 15.9 0.0 0.0075 15.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase zf-nanos PF05741.13 CDJ98213.1 - 0.15 12.3 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Nanos RNA binding domain Phage_NinH PF06322.11 CDJ98213.1 - 0.18 11.7 0.0 0.46 10.4 0.0 1.7 1 0 0 1 1 1 0 Phage NinH protein MAP17 PF15807.5 CDJ98214.1 - 0.007 16.6 8.2 0.007 16.6 8.2 2.1 1 1 1 2 2 2 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Presenilin PF01080.17 CDJ98214.1 - 0.043 12.6 16.6 0.06 12.1 16.6 1.3 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 CDJ98214.1 - 2.5 6.1 17.4 2.7 6.0 17.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AAA_11 PF13086.6 CDJ98214.1 - 2.7 7.7 17.0 3.3 7.4 17.0 1.1 1 0 0 1 1 1 0 AAA domain SLC12 PF03522.15 CDJ98214.1 - 9.6 5.1 18.6 12 4.8 18.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 FYVE PF01363.21 CDJ98215.1 - 1.3e-06 28.4 4.6 2.5e-06 27.5 4.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger Filament PF00038.21 CDJ98215.1 - 0.009 15.6 27.4 0.018 14.6 11.8 2.1 1 1 1 2 2 2 1 Intermediate filament protein CALCOCO1 PF07888.11 CDJ98215.1 - 0.01 14.8 31.0 0.025 13.5 30.6 1.8 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like HMMR_N PF15905.5 CDJ98215.1 - 0.015 14.8 27.9 0.37 10.2 25.7 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF724 PF05266.14 CDJ98215.1 - 0.019 14.8 2.3 0.019 14.8 2.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Tropomyosin PF00261.20 CDJ98215.1 - 0.04 13.3 36.0 0.29 10.5 4.2 3.1 1 1 2 3 3 3 0 Tropomyosin BLOC1_2 PF10046.9 CDJ98215.1 - 0.041 14.2 18.6 0.088 13.1 0.9 3.3 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.8 CDJ98215.1 - 0.12 12.5 28.1 0.27 11.3 3.5 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.7 CDJ98215.1 - 0.13 12.4 34.6 0.015 15.5 24.1 2.2 1 1 1 2 2 2 0 Tropomyosin like COG2 PF06148.11 CDJ98215.1 - 0.14 12.2 14.8 1.1 9.4 5.2 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Mis14 PF08641.12 CDJ98215.1 - 0.19 12.0 14.9 0.27 11.5 5.6 2.5 1 1 1 2 2 2 0 Kinetochore protein Mis14 like DUF812 PF05667.11 CDJ98215.1 - 0.22 10.4 26.0 0.37 9.6 26.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) NPV_P10 PF05531.12 CDJ98215.1 - 0.22 12.0 7.3 5.2 7.6 0.0 3.1 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein T3SSipB PF16535.5 CDJ98215.1 - 0.23 12.0 12.1 0.2 12.1 6.8 2.4 1 1 1 2 2 2 0 Type III cell invasion protein SipB DUF4407 PF14362.6 CDJ98215.1 - 0.26 10.6 12.6 0.36 10.1 12.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CC2-LZ PF16516.5 CDJ98215.1 - 0.28 11.5 21.1 1.4 9.3 3.9 3.5 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Seryl_tRNA_N PF02403.22 CDJ98215.1 - 0.38 11.0 24.3 1.6 9.0 9.9 2.9 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Lectin_N PF03954.14 CDJ98215.1 - 0.93 9.2 10.9 2.6 7.8 6.1 2.8 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Jnk-SapK_ap_N PF09744.9 CDJ98215.1 - 1 9.6 35.4 0.27 11.5 13.4 3.2 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Laminin_II PF06009.12 CDJ98215.1 - 1 9.4 16.9 2 8.4 2.5 2.6 1 1 1 2 2 2 0 Laminin Domain II CHD5 PF04420.14 CDJ98215.1 - 1.5 8.6 11.3 0.69 9.8 1.8 2.6 1 1 1 2 2 2 0 CHD5-like protein Fez1 PF06818.15 CDJ98215.1 - 1.9 8.9 27.6 16 5.9 12.0 2.3 1 1 1 2 2 2 0 Fez1 60KD_IMP PF02096.20 CDJ98215.1 - 2.7 7.9 7.9 5 7.0 0.1 2.7 2 1 1 3 3 3 0 60Kd inner membrane protein SpecificRecomb PF10136.9 CDJ98215.1 - 2.8 6.1 6.7 3.9 5.7 6.7 1.3 1 0 0 1 1 1 0 Site-specific recombinase AbiH PF14253.6 CDJ98215.1 - 3.1 7.6 9.6 4.2 7.2 9.5 1.4 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH GAS PF13851.6 CDJ98215.1 - 3.2 7.0 29.9 7.6 5.8 10.1 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Cauli_AT PF03233.13 CDJ98215.1 - 3.9 7.4 13.7 3.9 7.4 1.1 2.5 1 1 1 2 2 2 0 Aphid transmission protein Mod_r PF07200.13 CDJ98215.1 - 4.4 7.4 29.8 1.8 8.7 6.0 3.1 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein NAP PF00956.18 CDJ98218.1 - 2.7e-87 292.4 5.0 3.2e-87 292.1 5.0 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Collagen PF01391.18 CDJ98220.1 - 1.4e-16 60.0 112.1 7.9e-08 32.0 40.4 4.1 2 2 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ98220.1 - 2.4e-15 56.3 0.1 3.6e-15 55.8 0.1 1.3 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Bax1-I PF01027.20 CDJ98221.1 - 4.4e-43 147.5 16.9 4.4e-43 147.5 16.9 1.5 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 BolA PF01722.18 CDJ98221.1 - 1.2e-26 92.8 0.0 1.8e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein Ribosomal_L15e PF00827.17 CDJ98222.1 - 5.5e-90 300.2 12.5 6.4e-90 300.0 12.5 1.0 1 0 0 1 1 1 1 Ribosomal L15 Pkinase PF00069.25 CDJ98223.1 - 6.3e-16 58.5 0.1 1.1e-14 54.5 0.1 2.1 1 1 1 2 2 2 2 Protein kinase domain MADF_DNA_bdg PF10545.9 CDJ98223.1 - 3.2e-09 37.0 0.1 6.2e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Pkinase_Tyr PF07714.17 CDJ98223.1 - 1.2e-07 31.3 0.1 2e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Luteo_Vpg PF01659.16 CDJ98223.1 - 0.046 14.1 2.7 0.13 12.6 1.8 2.2 3 0 0 3 3 3 0 Luteovirus putative VPg genome linked protein NIF PF03031.18 CDJ98226.1 - 6.4e-43 146.2 0.0 8.8e-43 145.8 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sdh_cyt PF01127.22 CDJ98226.1 - 0.09 12.8 0.3 0.16 12.0 0.3 1.4 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF705 PF05152.12 CDJ98226.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF705) V_ATPase_I PF01496.19 CDJ98229.1 - 3.1e-291 968.1 19.1 1.2e-227 757.8 4.1 2.0 2 0 0 2 2 2 2 V-type ATPase 116kDa subunit family Occludin_ELL PF07303.13 CDJ98229.1 - 0.22 12.3 3.3 11 6.8 0.1 2.6 2 0 0 2 2 2 0 Occludin homology domain FTA4 PF13093.6 CDJ98229.1 - 0.52 10.2 4.3 1.3 8.9 4.1 1.6 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Alpha-amylase_C PF02806.18 CDJ98230.1 - 3.7e-24 85.0 0.1 2.3e-23 82.5 0.0 2.2 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 CDJ98230.1 - 1.4e-14 54.2 0.0 3.1e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 CDJ98230.1 - 2.1e-07 30.9 0.1 9.5e-05 22.1 0.1 2.2 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 CDJ98231.1 - 5.3e-24 84.5 0.0 3.3e-23 82.0 0.0 2.2 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 CDJ98231.1 - 7.9e-14 51.8 0.0 1.9e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 CDJ98231.1 - 1.9e-08 34.3 0.0 5.7e-05 22.8 0.1 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain DUF273 PF03314.14 CDJ98232.1 - 5e-21 75.3 2.2 1.1e-20 74.1 2.2 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Ets PF00178.22 CDJ98232.1 - 0.00053 20.4 0.8 0.002 18.5 0.1 2.2 2 0 0 2 2 2 1 Ets-domain Recep_L_domain PF01030.24 CDJ98233.1 - 1.7e-09 37.8 3.1 0.0012 18.9 0.1 3.4 2 1 1 3 3 3 3 Receptor L domain Recep_L_domain PF01030.24 CDJ98234.1 - 1.3e-14 54.2 0.2 4.7e-09 36.4 0.0 2.3 2 0 0 2 2 2 2 Receptor L domain PNMA PF14893.6 CDJ98235.1 - 0.019 14.4 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 PNMA RT_RNaseH PF17917.1 CDJ98236.1 - 6.4e-29 100.3 0.0 1.1e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ98236.1 - 5.9e-26 90.4 0.0 1.1e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ98236.1 - 5.2e-10 39.2 0.0 1.4e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ98236.1 - 6.2e-05 23.0 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain DNAPolymera_Pol PF11590.8 CDJ98236.1 - 0.0014 18.5 0.0 0.0036 17.1 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase catalytic subunit Pol Dala_Dala_lig_N PF01820.21 CDJ98236.1 - 0.12 12.9 0.0 1 9.9 0.0 2.4 3 0 0 3 3 3 0 D-ala D-ala ligase N-terminus Ras PF00071.22 CDJ98238.1 - 1.3e-54 184.1 0.0 1.6e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ98238.1 - 1.4e-31 109.2 0.0 1.9e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ98238.1 - 7e-12 45.1 0.0 1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CDJ98238.1 - 0.00025 21.0 0.2 0.46 10.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CDJ98238.1 - 0.0023 18.0 0.0 0.0036 17.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ98238.1 - 0.006 16.1 0.0 0.0094 15.5 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CDJ98238.1 - 0.0075 15.7 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CDJ98238.1 - 0.035 13.5 0.0 0.081 12.3 0.0 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 CDJ98238.1 - 0.04 13.5 0.0 0.81 9.2 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_24 PF13479.6 CDJ98238.1 - 0.095 12.4 0.1 0.36 10.5 0.1 1.8 2 0 0 2 2 2 0 AAA domain MANEC PF07502.14 CDJ98239.1 - 0.00015 22.0 3.8 0.00022 21.4 3.8 1.3 1 0 0 1 1 1 1 MANEC domain PAN_1 PF00024.26 CDJ98239.1 - 0.0038 17.2 2.5 0.0091 15.9 2.5 1.7 1 1 0 1 1 1 1 PAN domain PAN_4 PF14295.6 CDJ98239.1 - 0.0095 15.8 0.2 0.0095 15.8 0.2 1.9 2 0 0 2 2 2 1 PAN domain PRIMA1 PF16101.5 CDJ98239.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Fanconi_A PF03511.14 CDJ98239.1 - 0.091 12.7 0.2 0.88 9.5 0.2 2.1 2 0 0 2 2 2 0 Fanconi anaemia group A protein Epiglycanin_C PF14654.6 CDJ98239.1 - 0.13 12.4 0.5 0.5 10.5 0.0 1.9 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region SKG6 PF08693.10 CDJ98239.1 - 9.1 5.8 9.4 25 4.4 9.4 1.7 1 1 0 1 1 1 0 Transmembrane alpha-helix domain VPS13_mid_rpt PF16910.5 CDJ98240.1 - 1.4e-70 237.4 8.7 1.3e-51 175.3 0.0 5.9 5 1 0 5 5 5 3 Repeating coiled region of VPS13 VPS13 PF16908.5 CDJ98240.1 - 2.7e-66 223.7 5.5 4.7e-64 216.4 4.6 3.5 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 CDJ98240.1 - 1.6e-62 210.4 6.1 3.7e-59 199.5 0.2 3.4 2 1 1 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 CDJ98240.1 - 1e-36 125.6 0.3 5.6e-36 123.2 0.3 2.5 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 CDJ98240.1 - 2.1e-24 86.3 0.0 2.3e-23 82.9 0.0 2.6 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 ATG_C PF09333.11 CDJ98240.1 - 8.8e-09 35.6 0.0 4.8e-08 33.2 0.0 2.4 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain DUF5316 PF17247.2 CDJ98241.1 - 0.17 11.9 0.3 1 9.4 0.0 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5316) DDE_Tnp_1_7 PF13843.6 CDJ98242.1 - 9.2e-84 281.7 1.1 1.2e-83 281.3 1.1 1.2 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.21 CDJ98242.1 - 1.8e-05 24.5 0.1 3e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Transposase DDE domain IBR PF01485.21 CDJ98242.1 - 0.0035 17.5 8.5 0.0084 16.3 8.5 1.6 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain C1_4 PF07975.12 CDJ98242.1 - 0.17 12.1 8.4 0.41 10.9 8.4 1.6 1 0 0 1 1 1 0 TFIIH C1-like domain CEBP_ZZ PF16366.5 CDJ98242.1 - 0.85 9.9 9.8 2.2 8.6 9.8 1.7 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain C1_1 PF00130.22 CDJ98242.1 - 2.2 8.2 9.4 14 5.7 9.4 2.2 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF273 PF03314.14 CDJ98243.1 - 8.3e-63 211.9 0.7 1.1e-62 211.5 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Glyco_transf_34 PF05637.12 CDJ98243.1 - 0.013 15.3 0.2 0.072 12.8 0.2 2.0 1 1 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family Anp1 PF03452.14 CDJ98243.1 - 0.031 13.7 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Anp1 Tetraspanin PF00335.20 CDJ98244.1 - 3.1e-18 66.3 0.1 3.7e-18 66.1 0.1 1.0 1 0 0 1 1 1 1 Tetraspanin family TSP_1 PF00090.19 CDJ98245.1 - 3.3e-14 52.8 131.8 0.00072 19.7 8.9 10.5 10 3 0 10 10 10 7 Thrombospondin type 1 domain I-set PF07679.16 CDJ98245.1 - 5e-08 32.9 0.0 1.3e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ98245.1 - 2e-06 28.3 0.0 6.2e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CDJ98245.1 - 7.7e-06 26.0 0.0 1.7e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CDJ98245.1 - 7.7e-05 23.0 0.0 0.00025 21.3 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 CDJ98245.1 - 0.00041 20.5 0.1 0.13 12.5 0.0 2.5 1 1 1 2 2 2 2 Immunoglobulin V-set domain Ig_4 PF16680.5 CDJ98245.1 - 0.0024 18.1 0.1 0.0076 16.5 0.1 1.9 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 delta chain PLAC PF08686.11 CDJ98245.1 - 0.0036 18.0 9.5 0.017 15.9 9.5 2.3 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Transposase_1 PF01359.18 CDJ98247.1 - 2.8e-28 97.5 0.2 5.3e-28 96.7 0.2 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_48 PF17906.1 CDJ98247.1 - 9.8e-12 44.8 0.0 1.8e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase DDE_3 PF13358.6 CDJ98247.1 - 1.5e-06 28.0 0.2 2.1e-06 27.5 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 CDJ98247.1 - 0.0011 18.7 0.7 0.52 10.2 0.1 2.8 2 0 0 2 2 2 2 Homeodomain-like domain HTH_29 PF13551.6 CDJ98247.1 - 0.012 15.6 0.5 1.6 8.8 0.0 2.6 1 1 1 2 2 2 0 Winged helix-turn helix DUF4817 PF16087.5 CDJ98247.1 - 0.016 15.0 0.0 0.044 13.6 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) HTH_32 PF13565.6 CDJ98247.1 - 0.016 15.8 1.2 0.093 13.4 0.1 2.8 3 1 0 3 3 3 0 Homeodomain-like domain HTH_Tnp_IS630 PF01710.16 CDJ98247.1 - 0.016 15.2 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 Transposase HTH_50 PF18024.1 CDJ98247.1 - 0.016 14.8 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 CDJ98247.1 - 0.027 14.7 0.0 0.068 13.4 0.0 1.7 1 0 0 1 1 1 0 Transposase HTH_6 PF01418.17 CDJ98247.1 - 0.16 12.0 0.0 0.45 10.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family RVT_1 PF00078.27 CDJ98249.1 - 1.6e-35 122.7 0.0 2.5e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PAC3 PF10178.9 CDJ98250.1 - 0.0008 19.5 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 Lyase_N PF09092.11 CDJ98251.1 - 0.014 15.2 0.3 0.015 15.2 0.1 1.3 1 1 0 1 1 1 0 Lyase, N terminal FA_hydroxylase PF04116.13 CDJ98252.1 - 2.2e-14 54.0 16.4 2.2e-14 54.0 16.4 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Cyt-b5 PF00173.28 CDJ98252.1 - 7.5e-10 38.8 0.1 3.5e-09 36.7 0.0 2.1 2 1 1 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain TMEM189_B_dmain PF10520.9 CDJ98252.1 - 0.02 15.0 6.3 0.8 9.8 1.0 2.6 2 1 0 2 2 2 0 B domain of TMEM189, localisation domain Anth_synt_I_N PF04715.13 CDJ98252.1 - 0.12 12.6 0.2 0.24 11.6 0.2 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region Homeodomain PF00046.29 CDJ98254.1 - 6.2e-23 80.4 5.8 8.9e-23 79.9 5.8 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDJ98254.1 - 0.053 13.4 0.2 0.1 12.6 0.2 1.5 1 0 0 1 1 1 0 Homeobox KN domain QLQ PF08880.11 CDJ98254.1 - 0.13 12.1 0.2 0.13 12.1 0.2 1.9 2 0 0 2 2 2 0 QLQ SH3_6 PF12913.7 CDJ98254.1 - 0.18 11.4 0.1 0.36 10.4 0.1 1.5 1 0 0 1 1 1 0 SH3 domain (SH3b1 type) Ribosomal_S8e PF01201.22 CDJ98255.1 - 2.5e-50 170.2 3.6 4.8e-50 169.3 3.6 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e Septin PF00735.18 CDJ98256.1 - 2.6e-101 338.6 0.0 4.7e-101 337.8 0.0 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CDJ98256.1 - 3.9e-09 36.6 0.0 1.7e-08 34.5 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ98256.1 - 0.00017 21.5 1.8 0.018 15.0 0.4 3.1 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 CDJ98256.1 - 0.0011 19.0 7.3 0.46 10.5 0.2 3.6 3 1 1 4 4 4 2 Dynamin family GTP_EFTU PF00009.27 CDJ98256.1 - 0.0042 16.6 2.8 0.35 10.4 0.3 3.0 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain DASH_Spc19 PF08287.11 CDJ98256.1 - 0.0095 15.8 7.0 0.0095 15.8 7.0 1.7 2 0 0 2 2 2 1 Spc19 IIGP PF05049.13 CDJ98256.1 - 0.018 14.1 0.1 0.047 12.8 0.0 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 CDJ98256.1 - 0.029 13.7 0.0 0.073 12.4 0.0 1.7 1 0 0 1 1 1 0 AIG1 family TBCC_N PF16752.5 CDJ98256.1 - 0.032 14.7 4.5 0.068 13.6 4.5 1.5 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain ABC_tran PF00005.27 CDJ98256.1 - 0.051 14.1 0.4 0.32 11.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter DUF641 PF04859.12 CDJ98256.1 - 0.07 13.5 3.5 0.15 12.4 3.5 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Gtr1_RagA PF04670.12 CDJ98256.1 - 0.24 10.7 4.0 0.58 9.5 0.0 2.8 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region UPF0242 PF06785.11 CDJ98256.1 - 0.84 9.7 6.5 1.9 8.6 6.5 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 CDJ98256.1 - 1.1 8.3 5.4 1.7 7.6 5.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Y_phosphatase PF00102.27 CDJ98257.1 - 5.7e-41 140.6 0.2 7.6e-41 140.2 0.2 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase UPF0242 PF06785.11 CDJ98258.1 - 9e-05 22.7 9.8 0.00019 21.6 9.8 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus ERM PF00769.19 CDJ98258.1 - 0.00018 21.4 12.2 0.00024 21.0 12.2 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Fez1 PF06818.15 CDJ98258.1 - 0.00083 19.9 15.1 0.0011 19.4 15.1 1.3 1 1 0 1 1 1 1 Fez1 Membralin PF09746.9 CDJ98258.1 - 0.0026 16.9 0.0 0.0035 16.5 0.0 1.1 1 0 0 1 1 1 1 Tumour-associated protein DUF3340 PF11818.8 CDJ98258.1 - 0.0044 17.2 13.3 0.0076 16.4 13.3 1.5 1 0 0 1 1 1 1 C-terminal domain of tail specific protease (DUF3340) Csm1_N PF18504.1 CDJ98258.1 - 0.0053 17.1 4.7 0.0053 17.1 4.7 2.9 3 0 0 3 3 2 1 Csm1 N-terminal domain DUF724 PF05266.14 CDJ98258.1 - 0.014 15.3 10.6 0.024 14.5 10.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) HIP1_clath_bdg PF16515.5 CDJ98258.1 - 0.028 15.0 15.4 0.028 15.0 15.4 2.2 2 1 1 3 3 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 GAS PF13851.6 CDJ98258.1 - 0.071 12.4 24.0 0.54 9.6 4.2 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Leu_zip PF15294.6 CDJ98258.1 - 0.076 12.5 14.7 0.13 11.7 14.7 1.3 1 0 0 1 1 1 0 Leucine zipper DUF4201 PF13870.6 CDJ98258.1 - 0.1 12.4 16.2 0.064 13.0 13.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) APG6_N PF17675.1 CDJ98258.1 - 0.13 12.8 25.1 0.097 13.2 23.1 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region IFT57 PF10498.9 CDJ98258.1 - 0.13 11.2 10.6 0.2 10.6 10.6 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 YebO PF13974.6 CDJ98258.1 - 0.16 12.0 7.5 2.3 8.4 0.5 2.6 2 0 0 2 2 2 0 YebO-like protein V_ATPase_I PF01496.19 CDJ98258.1 - 0.2 9.6 3.4 0.23 9.3 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cnn_1N PF07989.11 CDJ98258.1 - 0.37 11.0 16.9 1.1 9.5 2.0 3.1 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 CDJ98258.1 - 0.4 10.5 18.5 0.12 12.2 2.3 2.9 1 1 2 3 3 3 0 Septum formation initiator VPS38 PF17649.1 CDJ98258.1 - 0.45 9.3 4.8 0.57 9.0 4.8 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 38 THOC7 PF05615.13 CDJ98258.1 - 0.48 10.7 19.2 13 6.1 19.2 2.2 1 1 0 1 1 1 0 Tho complex subunit 7 Borrelia_P83 PF05262.11 CDJ98258.1 - 0.54 8.7 11.2 0.79 8.1 11.2 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein HAUS6_N PF14661.6 CDJ98258.1 - 0.66 9.5 8.0 1.3 8.6 8.0 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus ARA70 PF12489.8 CDJ98258.1 - 1.3 9.2 9.7 2.6 8.2 9.7 1.4 1 0 0 1 1 1 0 Nuclear coactivator DUF3450 PF11932.8 CDJ98258.1 - 1.6 8.0 11.2 1.2 8.3 9.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Atg14 PF10186.9 CDJ98258.1 - 1.8 7.6 15.2 2.8 7.0 15.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 CDJ98258.1 - 1.9 7.3 24.2 13 4.6 24.2 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.10 CDJ98258.1 - 2.1 8.6 9.6 14 5.8 9.3 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Golgin_A5 PF09787.9 CDJ98258.1 - 2.4 7.5 16.0 3.8 6.9 16.0 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 JIP_LZII PF16471.5 CDJ98258.1 - 2.4 8.4 17.0 0.13 12.4 5.0 2.6 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II Syntaxin-6_N PF09177.11 CDJ98258.1 - 3.2 8.4 11.0 8.3 7.0 9.6 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FemAB PF02388.16 CDJ98258.1 - 7 5.4 8.5 9.9 4.9 8.5 1.3 1 0 0 1 1 1 0 FemAB family ADIP PF11559.8 CDJ98258.1 - 8.1 6.5 22.6 6.5 6.8 12.6 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Herpes_UL25 PF01499.16 CDJ98258.1 - 8.1 4.8 6.8 16 3.9 6.8 1.5 1 1 0 1 1 1 0 Herpesvirus UL25 family Rieske PF00355.26 CDJ98259.1 - 2.1e-17 62.8 0.0 4e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 CDJ98259.1 - 2.1e-09 37.2 0.0 3.5e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain DUF5021 PF16424.5 CDJ98259.1 - 0.17 11.7 0.0 0.4 10.5 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5021) Auts2 PF15336.6 CDJ98260.1 - 0.00033 20.9 8.9 0.00033 20.9 8.9 3.4 2 1 2 4 4 4 1 Autism susceptibility gene 2 protein TFIIA PF03153.13 CDJ98260.1 - 0.0028 17.7 24.9 0.0028 17.7 24.9 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Lipin_mid PF16876.5 CDJ98260.1 - 0.028 14.6 2.7 0.054 13.6 2.7 1.4 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain FHIPEP PF00771.20 CDJ98260.1 - 0.047 12.2 6.2 0.083 11.3 6.2 1.3 1 0 0 1 1 1 0 FHIPEP family DUF5421 PF17458.2 CDJ98260.1 - 0.062 12.7 5.9 0.11 11.9 5.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5421) ANAPC_CDC26 PF10471.9 CDJ98260.1 - 0.14 13.0 32.4 1.2 10.0 1.8 3.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF702 PF05142.12 CDJ98260.1 - 0.42 11.1 12.7 1.3 9.5 3.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DUF1980 PF09323.10 CDJ98260.1 - 0.69 9.8 2.7 2.2 8.2 2.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) eIF-3_zeta PF05091.12 CDJ98260.1 - 1.6 7.6 8.6 2.8 6.8 8.6 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CPSF100_C PF13299.6 CDJ98260.1 - 3.2 7.9 6.8 1.1 9.4 2.0 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 CDJ98260.1 - 5.6 5.6 9.4 7.4 5.2 9.4 1.4 1 1 0 1 1 1 0 Presenilin GET2 PF08690.10 CDJ98260.1 - 8.9 5.9 16.7 0.33 10.6 10.3 1.8 2 0 0 2 2 2 0 GET complex subunit GET2 MMR1 PF08505.10 CDJ98260.1 - 9.5 6.4 14.1 0.26 11.6 4.8 2.4 3 0 0 3 3 3 0 Mitochondrial Myo2 receptor-related protein MAT1 PF06391.13 CDJ98261.1 - 2.5 7.9 33.6 1.3 8.9 11.7 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF4615 PF15393.6 CDJ98261.1 - 7.7 7.1 28.0 0.53 10.9 7.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4615) Mit_KHE1 PF10173.9 CDJ98261.1 - 9.2 6.3 13.7 0.19 11.8 1.4 2.4 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related zf-C2H2_jaz PF12171.8 CDJ98262.1 - 0.053 13.8 51.2 0.85 10.0 3.0 11.7 10 0 0 10 10 10 0 Zinc-finger double-stranded RNA-binding Alba PF01918.21 CDJ98263.1 - 3.9e-11 42.6 0.0 6.8e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Alba ABC_tran_Xtn PF12848.7 CDJ98263.1 - 0.15 12.1 2.9 0.41 10.7 2.9 1.8 1 0 0 1 1 1 0 ABC transporter DFP PF04127.15 CDJ98264.1 - 3.6e-16 59.5 0.0 4.6e-09 36.4 0.0 2.4 2 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein HMG_box PF00505.19 CDJ98265.1 - 3.2e-17 62.7 1.6 3.2e-17 62.7 1.6 3.4 4 0 0 4 4 4 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ98265.1 - 3.4e-06 27.6 1.0 3.4e-06 27.6 1.0 2.6 2 1 0 2 2 2 1 HMG-box domain Prominin PF05478.11 CDJ98265.1 - 0.29 9.0 1.9 0.45 8.4 1.9 1.3 1 0 0 1 1 1 0 Prominin Staufen_C PF16482.5 CDJ98266.1 - 3.1e-10 40.2 0.0 6e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Staufen C-terminal domain Asp PF00026.23 CDJ98268.1 - 2.6e-87 293.2 1.3 3.1e-87 292.9 1.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ98268.1 - 3.4e-12 46.9 7.2 2.8e-11 44.0 7.2 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDJ98268.1 - 9.1e-06 25.5 0.0 6.9e-05 22.7 0.0 2.4 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CDJ98268.1 - 0.15 12.7 0.1 24 5.7 0.0 3.1 3 0 0 3 3 3 0 Aspartyl protease Motile_Sperm PF00635.26 CDJ98269.1 - 8.4e-20 70.7 0.9 2.4e-19 69.2 0.0 2.2 2 1 0 2 2 2 1 MSP (Major sperm protein) domain AAA_12 PF13087.6 CDJ98270.1 - 3.8e-10 39.7 0.0 8.6e-10 38.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ98270.1 - 2e-07 30.9 0.3 0.0018 18.0 0.6 2.3 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 CDJ98270.1 - 8.6e-07 29.0 0.0 2.7e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ98270.1 - 9.9e-06 25.9 0.1 3.2e-05 24.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 CDJ98270.1 - 0.02 14.8 0.3 0.69 9.7 0.1 2.3 1 1 0 2 2 2 0 Helicase RVT_1 PF00078.27 CDJ98271.1 - 3.6e-09 36.5 0.0 5.8e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Telomerase_RBD PF12009.8 CDJ98271.1 - 0.00025 21.1 0.8 0.002 18.2 0.1 2.5 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain PHA_synth_III_E PF09712.10 CDJ98271.1 - 0.032 13.3 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Histone PF00125.24 CDJ98273.1 - 2.7e-17 63.4 1.3 2.9e-17 63.3 1.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 CDJ98273.1 - 0.00012 22.6 2.9 0.00014 22.5 2.9 1.0 1 0 0 1 1 1 1 PCNA-associated factor histone like domain UPF0016 PF01169.19 CDJ98274.1 - 1.2e-40 137.7 14.4 4.2e-22 78.3 7.0 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 CDJ98274.1 - 0.025 14.4 4.1 0.09 12.5 4.1 2.0 1 1 0 1 1 1 0 Putative manganese efflux pump CWC25 PF12542.8 CDJ98275.1 - 2.8e-13 50.6 0.1 2.8e-13 50.6 0.1 4.6 3 2 0 3 3 3 1 Pre-mRNA splicing factor Integrin_beta PF00362.18 CDJ98276.1 - 4.8e-104 347.4 0.0 6.7e-104 346.9 0.0 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.11 CDJ98276.1 - 3.2e-21 74.7 1.0 7e-21 73.7 1.0 1.6 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.12 CDJ98276.1 - 7.6e-18 64.8 2.7 7.6e-18 64.8 2.7 3.9 4 1 2 6 6 6 1 Integrin beta tail domain PSI_integrin PF17205.3 CDJ98276.1 - 4.9e-09 35.8 7.1 4.9e-09 35.8 7.1 4.1 3 0 0 3 3 3 1 Integrin plexin domain EGF_2 PF07974.13 CDJ98276.1 - 5.1e-07 30.0 86.5 9.3e-05 22.7 13.1 6.2 5 1 0 5 5 5 3 EGF-like domain I-EGF_1 PF18372.1 CDJ98276.1 - 0.0014 18.6 73.9 0.09 12.9 7.2 5.9 6 0 0 6 6 6 4 Integrin beta epidermal growth factor like domain 1 CusF_Ec PF11604.8 CDJ98276.1 - 0.2 11.7 0.0 3.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Copper binding periplasmic protein CusF Collectrin PF16959.5 CDJ98276.1 - 0.36 10.6 1.7 0.78 9.5 1.7 1.5 1 0 0 1 1 1 0 Renal amino acid transporter Rib_5-P_isom_A PF06026.14 CDJ98277.1 - 8.7e-59 198.0 0.0 1.2e-58 197.6 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 CDJ98277.1 - 0.076 13.0 0.0 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain Sugar-bind PF04198.13 CDJ98277.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain ELO PF01151.18 CDJ98278.1 - 1.2e-63 215.0 25.3 1.4e-63 214.7 25.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family HlyD_D23 PF16576.5 CDJ98279.1 - 0.26 10.5 2.6 0.4 9.8 2.6 1.2 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Radial_spoke_3 PF06098.11 CDJ98279.1 - 2.6 7.2 10.8 3.1 7.0 10.4 1.4 1 1 0 1 1 1 0 Radial spoke protein 3 Med30 PF11315.8 CDJ98279.1 - 3.7 7.7 8.0 4.1 7.6 7.1 1.4 1 1 0 1 1 1 0 Mediator complex subunit 30 Pkinase PF00069.25 CDJ98280.1 - 1.5e-53 181.9 0.0 1.9e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ98280.1 - 8.3e-27 94.1 0.0 1.2e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ98280.1 - 0.0099 14.8 0.1 0.019 13.9 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CDJ98280.1 - 0.032 13.5 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RRM_1 PF00076.22 CDJ98281.1 - 0.015 15.1 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PDZ PF00595.24 CDJ98282.1 - 4.7e-20 71.7 0.0 7.3e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDJ98282.1 - 1.4e-06 28.0 0.0 2.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PAP1 PF08601.10 CDJ98282.1 - 0.0025 17.6 9.5 0.003 17.4 9.5 1.1 1 0 0 1 1 1 1 Transcription factor PAP1 PDZ_2 PF13180.6 CDJ98282.1 - 0.009 16.3 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 1 PDZ domain FAM60A PF15396.6 CDJ98283.1 - 9.1 6.2 23.8 10 6.0 23.8 1.0 1 0 0 1 1 1 0 Protein Family FAM60A FERM_C PF09380.10 CDJ98284.1 - 7.6e-21 74.3 0.0 1.5e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 CDJ98284.1 - 5.9e-20 71.0 0.2 6.4e-18 64.5 0.1 2.6 2 0 0 2 2 2 1 FERM N-terminal domain FERM_M PF00373.18 CDJ98284.1 - 1e-19 71.1 0.0 1.6e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 FERM central domain FA PF08736.11 CDJ98284.1 - 2.6e-13 49.8 0.6 5.1e-13 48.9 0.6 1.5 1 0 0 1 1 1 1 FERM adjacent (FA) SCVP PF17619.2 CDJ98285.1 - 2.2e-78 259.2 8.6 4.7e-23 81.9 0.5 4.6 5 0 0 5 5 5 4 Secreted clade V proteins Mucin PF01456.17 CDJ98285.1 - 1.2e-06 28.6 58.5 2e-05 24.6 31.0 3.3 3 0 0 3 3 3 2 Mucin-like glycoprotein Otopetrin PF03189.13 CDJ98285.1 - 0.0065 15.3 0.2 0.034 13.0 0.4 1.9 2 0 0 2 2 2 1 Otopetrin DUF4227 PF14004.6 CDJ98285.1 - 0.11 12.5 1.4 29 4.7 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4227) DUF1242 PF06842.12 CDJ98285.1 - 0.11 12.3 7.7 4.1 7.3 0.2 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1242) RII_binding_1 PF10522.9 CDJ98285.1 - 0.23 11.8 0.4 1.3e+02 3.2 0.0 4.4 5 0 0 5 5 5 0 RII binding domain tRNA_bind_2 PF13725.6 CDJ98285.1 - 0.28 10.8 0.4 75 2.9 0.0 3.0 3 0 0 3 3 3 0 Possible tRNA binding domain MGC-24 PF05283.11 CDJ98285.1 - 0.63 10.5 30.7 0.39 11.1 13.9 3.2 3 0 0 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3094 PF11293.8 CDJ98285.1 - 0.96 9.2 7.8 22 4.9 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3094) MIF4G PF02854.19 CDJ98286.1 - 7e-11 42.2 3.5 1.8e-10 40.8 3.5 1.7 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 CDJ98286.1 - 2.3e-09 37.2 0.1 2.3e-09 37.2 0.1 2.9 3 1 0 3 3 3 1 MA3 domain BUD22 PF09073.10 CDJ98286.1 - 1.8 7.8 29.8 3.1 7.0 29.8 1.4 1 0 0 1 1 1 0 BUD22 DUF629 PF04780.12 CDJ98287.1 - 0.0095 14.5 0.7 0.016 13.8 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF629) RT_RNaseH PF17917.1 CDJ98288.1 - 3.1e-33 114.2 0.0 5.7e-33 113.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ98288.1 - 1.8e-25 88.8 0.0 6.4e-25 87.1 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ98288.1 - 3.1e-17 62.4 0.9 8.7e-17 61.0 0.9 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDJ98288.1 - 4.6e-11 42.9 1.0 2e-10 40.9 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain LEAP-2 PF07359.11 CDJ98290.1 - 0.12 12.3 0.1 0.33 10.8 0.1 1.8 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) PAS_11 PF14598.6 CDJ98291.1 - 3.9e-18 65.6 0.1 2.1e-14 53.6 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 CDJ98291.1 - 4.9e-15 55.6 0.0 2.1e-09 37.6 0.0 2.5 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 CDJ98291.1 - 5e-14 52.0 1.4 9.5e-14 51.1 1.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS PF00989.25 CDJ98291.1 - 8.3e-12 45.1 0.0 8.6e-07 29.0 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 CDJ98291.1 - 9.8e-09 35.4 0.0 0.0005 20.3 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 CDJ98291.1 - 1.7e-06 28.2 0.0 0.0079 16.4 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.11 CDJ98291.1 - 0.00077 20.1 0.0 1.9 9.2 0.0 2.4 2 0 0 2 2 2 2 PAS fold HEPN_Cthe2314 PF18730.1 CDJ98291.1 - 0.028 14.5 0.3 0.057 13.5 0.3 1.6 1 0 0 1 1 1 0 Cthe_2314-like HEPN PAS_12 PF18095.1 CDJ98291.1 - 0.13 11.9 0.0 4.6 6.9 0.0 2.2 2 0 0 2 2 2 0 UPF0242 C-terminal PAS-like domain VWA PF00092.28 CDJ98292.1 - 6.2e-10 39.6 0.0 1.2e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CDJ98292.1 - 8.6e-08 32.8 0.0 2.1e-07 31.6 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 CDJ98295.1 - 0.00027 21.2 0.0 0.00048 20.4 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CDJ98295.1 - 0.0005 20.7 0.0 0.00081 20.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Astacin PF01400.24 CDJ98296.1 - 1.1e-57 194.7 0.1 1.5e-57 194.4 0.1 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 CDJ98296.1 - 0.0013 18.4 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CDJ98296.1 - 0.0075 16.4 0.7 0.14 12.3 0.6 2.3 1 1 0 2 2 2 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 CDJ98296.1 - 0.02 14.7 0.6 0.32 10.8 0.2 2.3 1 1 1 2 2 2 0 Matrixin DUF4953 PF16313.5 CDJ98296.1 - 0.075 12.2 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M57 PF12388.8 CDJ98296.1 - 0.088 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_3 PF13582.6 CDJ98296.1 - 0.14 12.7 0.7 0.41 11.2 0.2 2.0 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 CDJ98297.1 - 5.3e-57 192.5 0.1 7.9e-57 192.0 0.1 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 CDJ98297.1 - 0.003 17.2 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CDJ98297.1 - 0.024 14.8 0.7 0.27 11.4 0.5 2.3 1 1 1 2 2 2 0 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 CDJ98297.1 - 0.024 14.5 0.4 0.68 9.8 0.2 2.3 1 1 1 2 2 2 0 Matrixin DUF4953 PF16313.5 CDJ98297.1 - 0.13 11.4 0.1 0.22 10.7 0.1 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M57 PF12388.8 CDJ98297.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase TGF_beta PF00019.20 CDJ98299.1 - 2.7e-24 86.1 2.9 2.7e-24 86.1 2.9 1.9 1 1 1 2 2 2 1 Transforming growth factor beta like domain TRAPPC10 PF12584.8 CDJ98300.1 - 0.00012 21.8 0.0 0.00025 20.8 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun PF07919.12 CDJ98300.1 - 0.0021 16.9 0.1 0.0061 15.4 0.0 1.6 2 0 0 2 2 2 1 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.7 CDJ98300.1 - 0.007 16.3 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking Bac_rhamnosid_C PF17390.2 CDJ98300.1 - 0.097 12.5 0.0 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase C-terminal domain MFS_1 PF07690.16 CDJ98301.1 - 7.9e-55 186.2 35.1 9.1e-54 182.7 29.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DEAD PF00270.29 CDJ98302.1 - 4.8e-37 127.4 0.0 1.2e-36 126.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ98302.1 - 9.8e-22 77.4 0.0 4.9e-21 75.1 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CDJ98302.1 - 1e-16 60.9 0.0 3.5e-16 59.2 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CDJ98302.1 - 3.2e-08 33.7 1.7 6.7e-08 32.7 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 CDJ98302.1 - 1.6e-05 25.2 0.5 6.7e-05 23.1 0.0 2.2 3 0 0 3 3 3 1 Helicase C-terminal domain ERCC3_RAD25_C PF16203.5 CDJ98302.1 - 0.0062 15.8 1.8 0.015 14.5 0.0 2.1 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 CDJ98302.1 - 0.0091 16.3 0.5 0.34 11.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain TP53IP5 PF15331.6 CDJ98302.1 - 0.29 11.2 7.9 0.6 10.2 7.9 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Transposase_1 PF01359.18 CDJ98303.1 - 7.4e-31 105.8 0.0 1.6e-30 104.7 0.0 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) PP2C PF00481.21 CDJ98303.1 - 1.9e-26 93.2 0.0 2.9e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C HTH_48 PF17906.1 CDJ98303.1 - 2.1e-08 34.2 0.2 4.6e-08 33.1 0.2 1.6 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_Tnp_IS630 PF01710.16 CDJ98303.1 - 0.00066 19.7 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 CDJ98303.1 - 0.0044 17.1 0.1 0.013 15.6 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 CDJ98303.1 - 0.0082 16.7 2.9 0.023 15.3 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain PP2C_2 PF13672.6 CDJ98303.1 - 0.011 15.4 0.1 0.038 13.6 0.1 1.9 1 1 0 1 1 1 0 Protein phosphatase 2C HTH_24 PF13412.6 CDJ98303.1 - 0.016 14.7 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 CDJ98303.1 - 0.29 11.0 1.5 1.7 8.6 0.1 2.8 3 0 0 3 3 3 0 Homeodomain-like domain tRNA-synt_1d PF00750.19 CDJ98304.1 - 1.1e-131 438.9 0.1 1.8e-131 438.2 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 CDJ98304.1 - 4.8e-27 94.5 0.1 1.9e-26 92.6 0.0 2.1 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 CDJ98304.1 - 3.4e-19 69.2 0.0 1.1e-18 67.6 0.0 2.0 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 CDJ98304.1 - 0.0092 15.4 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF5375 PF17345.2 CDJ98304.1 - 0.093 12.6 0.0 0.27 11.1 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5375) DIT1_PvcA PF05141.12 CDJ98304.1 - 0.15 11.5 0.6 0.58 9.6 0.3 2.0 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein SDP_N PF12278.8 CDJ98304.1 - 0.62 10.2 2.5 5.4 7.1 1.0 2.4 2 0 0 2 2 2 0 Sex determination protein N terminal RNA_pol_Rpb8 PF03870.15 CDJ98305.1 - 2e-48 164.1 0.0 2.2e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 CDJ98305.1 - 0.012 15.7 0.2 0.93 9.6 0.0 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase, subunit G DUF1758 PF05585.12 CDJ98306.1 - 5.3e-07 29.6 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 CDJ98306.1 - 2.1e-05 25.1 0.0 4.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ98306.1 - 0.00057 20.4 0.0 0.0013 19.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ98306.1 - 0.033 14.5 0.1 2.2 8.7 0.0 2.8 3 0 0 3 3 3 0 Retroviral aspartyl protease RVP_2 PF08284.11 CDJ98306.1 - 0.079 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease ATG22 PF11700.8 CDJ98306.1 - 0.21 10.2 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Transposase_1 PF01359.18 CDJ98307.1 - 4.5e-20 71.2 0.1 7.6e-20 70.5 0.1 1.3 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_48 PF17906.1 CDJ98307.1 - 4.3e-18 65.2 0.9 8.3e-18 64.3 0.9 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 CDJ98307.1 - 2.5e-05 24.8 0.2 0.00029 21.4 0.1 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 CDJ98307.1 - 0.0017 18.1 0.9 0.073 12.9 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain HTH_DeoR PF08220.12 CDJ98307.1 - 0.0063 16.2 0.1 0.016 14.9 0.1 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_5 PF01022.20 CDJ98307.1 - 0.011 15.5 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 CDJ98307.1 - 0.016 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 CDJ98307.1 - 0.019 15.2 0.5 0.037 14.3 0.1 1.8 2 0 0 2 2 2 0 Transposase Phage_terminase PF10668.9 CDJ98307.1 - 0.051 13.6 0.2 1 9.5 0.1 2.3 2 0 0 2 2 2 0 Phage terminase small subunit TrmB PF01978.19 CDJ98307.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 CDJ98307.1 - 0.085 12.9 0.1 0.22 11.6 0.1 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_IclR PF09339.10 CDJ98307.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_10 PF04967.12 CDJ98307.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain KxDL PF10241.9 CDJ98308.1 - 4.6e-25 87.7 2.1 5.9e-25 87.4 2.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF29 PF01724.16 CDJ98308.1 - 0.026 14.8 1.7 0.033 14.4 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF29 CLTH PF10607.9 CDJ98308.1 - 0.12 12.3 1.7 1.9 8.4 0.4 2.0 1 1 1 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain zf-CCHC_3 PF13917.6 CDJ98309.1 - 3.4e-06 26.9 0.1 8.5e-06 25.6 0.1 1.7 1 0 0 1 1 1 1 Zinc knuckle Rtf2 PF04641.12 CDJ98309.1 - 0.0014 18.0 19.7 0.0018 17.7 19.7 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger DUF4820 PF16091.5 CDJ98309.1 - 0.018 14.4 8.6 0.025 14.0 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DDHD PF02862.17 CDJ98309.1 - 0.034 14.3 4.7 0.036 14.2 4.7 1.3 1 0 0 1 1 1 0 DDHD domain Endostatin PF06482.11 CDJ98309.1 - 0.041 13.3 7.1 0.046 13.2 7.1 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin zf-CCHC PF00098.23 CDJ98309.1 - 0.15 12.2 2.9 0.24 11.5 2.9 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF913 PF06025.12 CDJ98309.1 - 0.46 9.4 7.0 0.5 9.3 7.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Neur_chan_memb PF02932.16 CDJ98309.1 - 1.4 8.9 7.0 1.4 9.0 7.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 CDJ98309.1 - 2.6 6.2 18.3 3 6.0 18.3 1.1 1 0 0 1 1 1 0 CDC45-like protein GNAT_acetyltr_2 PF13718.6 CDJ98309.1 - 3.8 6.8 11.3 1.3e+02 1.9 11.3 2.0 1 1 0 1 1 1 0 GNAT acetyltransferase 2 SelP_N PF04592.14 CDJ98309.1 - 4.2 6.7 17.3 5.6 6.3 17.3 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Membralin PF09746.9 CDJ98309.1 - 7.6 5.5 10.1 8.9 5.2 10.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein RR_TM4-6 PF06459.12 CDJ98309.1 - 8.4 6.1 22.5 7.2 6.3 21.5 1.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Dsh_C PF12316.8 CDJ98309.1 - 9.6 6.5 17.5 0.65 10.4 12.1 1.7 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal COBRA1 PF06209.13 CDJ98310.1 - 2.7e-72 244.2 2.7 3.6e-72 243.8 2.7 1.1 1 0 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) ART PF01129.18 CDJ98310.1 - 0.064 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase SprT-like PF10263.9 CDJ98311.1 - 2.4e-27 95.0 0.0 4e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 SprT-like family Ground-like PF04155.18 CDJ98312.1 - 1.1e-17 64.4 0.3 2.9e-17 63.1 0.3 1.7 2 0 0 2 2 2 1 Ground-like domain Fringe PF02434.16 CDJ98313.1 - 1.8e-11 44.0 1.8 2.3e-10 40.3 1.8 2.5 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 CDJ98313.1 - 9.9e-10 38.6 1.1 4.8e-06 26.5 1.0 2.2 1 1 1 2 2 2 2 Galactosyltransferase Vps39_1 PF10366.9 CDJ98314.1 - 2.8e-28 98.4 5.2 6e-28 97.3 1.0 2.8 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 CDJ98314.1 - 6.3e-22 78.1 0.1 2.2e-21 76.4 0.1 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 CDJ98314.1 - 1.6e-08 34.6 6.4 0.00028 20.8 1.3 2.8 2 1 0 2 2 2 2 Region in Clathrin and VPS CNH PF00780.22 CDJ98314.1 - 1.1e-06 28.5 0.0 2.6e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 CNH domain Thioredoxin PF00085.20 CDJ98315.1 - 1e-23 83.3 0.0 1.3e-23 83.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CDJ98315.1 - 3.4e-07 30.7 0.1 3.7e-06 27.3 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CDJ98315.1 - 5.5e-05 23.3 0.0 8.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 CDJ98315.1 - 0.00046 20.5 0.0 0.047 14.0 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 CDJ98315.1 - 0.012 15.6 0.0 0.035 14.0 0.0 1.7 1 1 1 2 2 2 0 AhpC/TSA family Thioredoxin_3 PF13192.6 CDJ98315.1 - 0.051 13.6 0.1 0.091 12.8 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin domain HyaE PF07449.11 CDJ98315.1 - 0.085 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Epimerase PF01370.21 CDJ98316.1 - 3.1e-21 76.0 0.0 4.1e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CDJ98316.1 - 8.9e-15 54.9 0.1 2e-12 47.2 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CDJ98316.1 - 1.8e-10 40.4 0.0 2.7e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 CDJ98316.1 - 5e-09 35.6 0.0 7.2e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CDJ98316.1 - 1.3e-06 27.8 0.0 4.2e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 CDJ98316.1 - 1.4e-05 24.4 0.4 0.00024 20.4 0.4 2.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Asp PF00026.23 CDJ98317.1 - 1.1e-68 232.0 0.1 1.8e-68 231.3 0.1 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ98317.1 - 2.5e-11 44.2 4.4 4.5e-11 43.3 4.4 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Ribosomal_S4e PF00900.20 CDJ98318.1 - 1.7e-33 114.3 1.1 4.2e-32 109.9 1.6 2.4 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.12 CDJ98318.1 - 7e-21 74.1 5.7 1.3e-20 73.1 5.7 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain 40S_S4_C PF16121.5 CDJ98318.1 - 8.2e-15 54.2 0.1 2e-14 52.9 0.1 1.7 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus TruB_N PF01509.18 CDJ98318.1 - 2e-09 37.9 0.0 5.1e-09 36.7 0.0 1.6 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) S4 PF01479.25 CDJ98318.1 - 3e-06 26.8 0.0 3e-06 26.8 0.0 2.6 3 0 0 3 3 3 1 S4 domain KOW PF00467.29 CDJ98318.1 - 0.01 15.8 0.7 0.01 15.8 0.7 2.6 2 0 0 2 2 2 0 KOW motif DUF1730 PF08331.10 CDJ98318.1 - 0.053 13.4 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) TruB_C_2 PF16198.5 CDJ98318.1 - 0.056 13.6 0.3 0.15 12.2 0.1 1.8 2 0 0 2 2 2 0 tRNA pseudouridylate synthase B C-terminal domain Sipho_tail PF05709.11 CDJ98318.1 - 0.14 11.5 0.1 0.28 10.6 0.1 1.5 1 0 0 1 1 1 0 Phage tail protein Pkinase_Tyr PF07714.17 CDJ98319.1 - 1.6e-69 234.1 0.0 2.4e-69 233.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ98319.1 - 3e-42 144.8 0.0 4.6e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDJ98319.1 - 3.9e-05 23.7 1.5 0.00042 20.4 0.5 2.7 2 1 0 2 2 2 1 SH2 domain Kinase-like PF14531.6 CDJ98319.1 - 0.02 14.2 0.0 0.052 12.9 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Alpha-2-MRAP_C PF06401.11 CDJ98320.1 - 1.5e-25 90.4 29.4 1.5e-25 90.4 29.4 2.4 2 1 0 2 2 2 2 Alpha-2-macroglobulin RAP, C-terminal domain Alpha-2-MRAP_N PF06400.11 CDJ98320.1 - 2.8e-09 37.0 31.4 9.3e-06 25.6 6.7 3.6 2 2 1 3 3 3 2 Alpha-2-macroglobulin RAP, N-terminal domain PriCT_1 PF08708.11 CDJ98320.1 - 0.069 12.9 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) WXG100 PF06013.12 CDJ98320.1 - 0.18 12.0 3.0 3.7 7.8 0.1 3.1 3 0 0 3 3 3 0 Proteins of 100 residues with WXG AKNA PF12443.8 CDJ98320.1 - 0.29 11.8 7.2 0.076 13.7 1.5 2.9 1 1 3 4 4 4 0 AT-hook-containing transcription factor Vps54 PF07928.12 CDJ98320.1 - 3.1 8.3 8.0 1.8 9.0 1.1 2.8 2 1 0 2 2 2 0 Vps54-like protein PspB PF06667.12 CDJ98320.1 - 5.1 7.2 7.2 32 4.7 1.2 3.5 3 1 0 3 3 3 0 Phage shock protein B CH PF00307.31 CDJ98321.1 - 6.6e-09 35.9 0.0 1.3e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain NT-C2 PF10358.9 CDJ98321.1 - 6.8e-08 32.4 0.1 1.1e-07 31.7 0.1 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins CAMSAP_CH PF11971.8 CDJ98321.1 - 9.4e-06 25.4 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain GREB1 PF15782.5 CDJ98321.1 - 0.0021 15.3 4.2 0.0027 14.9 4.2 1.0 1 0 0 1 1 1 1 Gene regulated by oestrogen in breast cancer Fumarate_red_D PF02313.17 CDJ98324.1 - 0.0021 18.2 0.2 0.0021 18.2 0.2 1.9 2 1 0 2 2 2 1 Fumarate reductase subunit D DUF3087 PF11286.8 CDJ98325.1 - 0.69 9.4 4.7 0.28 10.7 1.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3087) DB PF01682.19 CDJ98326.1 - 2.5e-24 85.5 14.1 4.6e-24 84.6 14.1 1.4 1 0 0 1 1 1 1 DB module BTB PF00651.31 CDJ98327.1 - 2.7e-13 50.1 0.0 4.7e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Laminin_EGF PF00053.24 CDJ98328.1 - 0.0032 17.6 0.3 0.0054 16.9 0.3 1.4 1 0 0 1 1 1 1 Laminin EGF domain Hint PF01079.20 CDJ98329.1 - 8.7e-19 67.9 0.0 1.4e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Hint module Vint PF14623.6 CDJ98329.1 - 0.0022 17.8 0.0 0.0035 17.2 0.0 1.2 1 0 0 1 1 1 1 Hint-domain Ion_trans_2 PF07885.16 CDJ98330.1 - 9.5e-28 96.0 12.6 4.7e-17 61.7 4.3 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 CDJ98330.1 - 4.8e-05 22.7 12.6 0.0045 16.2 6.3 2.2 1 1 0 2 2 2 2 Ion transport protein IRK PF01007.20 CDJ98330.1 - 0.019 14.8 6.0 0.7 9.7 0.0 2.5 2 1 1 3 3 3 0 Inward rectifier potassium channel transmembrane domain HA2 PF04408.23 CDJ98331.1 - 2.3e-21 76.1 0.0 4.8e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CDJ98331.1 - 1.2e-15 57.8 0.0 2.9e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CDJ98331.1 - 1.7e-07 31.5 0.0 3.8e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CDJ98331.1 - 6.3e-05 22.8 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDJ98331.1 - 0.00077 19.7 0.1 0.0047 17.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ98331.1 - 0.07 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDJ98331.1 - 0.084 13.4 0.4 0.49 10.9 0.4 2.1 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 CDJ98331.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region P34-Arc PF04045.14 CDJ98332.1 - 4.2e-102 341.0 0.0 5e-102 340.7 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 CDJ98332.1 - 0.016 14.8 0.1 0.071 12.7 0.1 2.1 2 1 0 2 2 2 0 ARP2/3 complex 20 kDa subunit (ARPC4) Sdh_cyt PF01127.22 CDJ98333.1 - 7.2e-22 77.7 3.0 1.8e-21 76.4 3.0 1.6 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Bcl-2 PF00452.19 CDJ98333.1 - 9.6e-13 48.7 0.1 2.2e-12 47.5 0.1 1.6 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family BH4 PF02180.17 CDJ98333.1 - 2.5e-06 27.2 0.0 6.6e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Bcl-2 homology region 4 AAA_12 PF13087.6 CDJ98334.1 - 7.2e-36 123.7 0.0 1.1e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ98334.1 - 2.4e-05 24.2 0.1 0.51 10.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 CDJ98334.1 - 5.5e-05 23.0 0.0 0.32 10.7 0.0 2.7 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 CDJ98334.1 - 0.00014 21.7 0.0 0.14 11.9 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 CDJ98334.1 - 0.0039 17.5 0.1 0.058 13.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 CDJ98334.1 - 0.096 12.5 0.0 0.27 11.1 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Drf_DAD PF06345.11 CDJ98334.1 - 0.13 12.4 1.1 23 5.3 0.1 2.6 2 0 0 2 2 2 0 DRF Autoregulatory Domain AAA_12 PF13087.6 CDJ98335.1 - 2.2e-34 118.9 0.0 3.5e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ98335.1 - 2.1e-06 27.8 0.0 8.4e-05 22.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CDJ98335.1 - 3.7e-05 23.5 0.0 0.22 11.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 CDJ98335.1 - 0.0024 17.6 0.1 0.51 10.0 0.1 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 CDJ98335.1 - 0.013 15.9 0.3 0.15 12.3 0.1 2.5 2 1 0 2 2 2 0 AAA domain US2 PF02476.15 CDJ98335.1 - 0.03 15.0 0.0 0.085 13.6 0.0 1.7 1 0 0 1 1 1 0 US2 family GBP_repeat PF02526.14 CDJ98335.1 - 0.12 12.1 0.6 0.33 10.7 0.0 2.0 2 0 0 2 2 2 0 Glycophorin-binding protein CBFD_NFYB_HMF PF00808.23 CDJ98336.1 - 7.1e-13 48.6 0.0 1.5e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDJ98336.1 - 1.6e-06 28.5 1.0 5.3e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 CDJ98336.1 - 0.017 15.3 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) UPF0542 PF15086.6 CDJ98336.1 - 0.18 11.8 0.7 0.32 10.9 0.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Cyt-b5 PF00173.28 CDJ98337.1 - 1.7e-11 44.1 0.2 3e-11 43.3 0.2 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Snf7 PF03357.21 CDJ98339.1 - 1e-34 119.6 14.4 1.3e-34 119.3 14.4 1.1 1 0 0 1 1 1 1 Snf7 RNase_H_2 PF13482.6 CDJ98339.1 - 0.082 12.9 1.0 0.11 12.4 1.0 1.2 1 0 0 1 1 1 0 RNase_H superfamily Peptidase_S66C PF17676.1 CDJ98339.1 - 0.11 13.0 0.7 6.8 7.2 0.1 2.3 1 1 1 2 2 2 0 LD-carboxypeptidase C-terminal domain pEK499_p136 PF18736.1 CDJ98339.1 - 0.18 11.5 3.7 1.1 8.9 0.1 2.8 2 1 0 3 3 3 0 HEPN pEK499 p136 Hydantoinase_B PF02538.14 CDJ98339.1 - 0.37 9.2 1.8 0.46 8.8 1.8 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase PHM7_cyt PF14703.6 CDJ98339.1 - 7.4 6.8 8.7 1.5 9.0 0.2 2.2 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DEAD PF00270.29 CDJ98340.1 - 1.5e-45 155.1 0.0 2.5e-45 154.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ98340.1 - 4.3e-32 110.8 0.1 8.7e-31 106.6 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ98340.1 - 0.0028 17.7 0.0 0.005 16.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 CDJ98340.1 - 0.031 13.0 0.0 0.068 11.9 0.0 1.4 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 zf-C2H2_2 PF12756.7 CDJ98341.1 - 5.9e-06 26.5 10.3 0.00053 20.3 0.3 2.2 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 CDJ98341.1 - 0.0046 17.3 0.5 0.0046 17.3 0.5 2.3 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-C2HE PF16278.5 CDJ98341.1 - 0.0068 16.8 2.2 0.14 12.6 0.3 2.5 1 1 1 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_4 PF13894.6 CDJ98341.1 - 0.016 16.0 0.1 0.016 16.0 0.1 2.5 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ98341.1 - 0.029 14.6 0.1 0.073 13.4 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding ROS_MUCR PF05443.11 CDJ98341.1 - 0.035 14.2 0.6 4.2 7.4 0.0 2.4 1 1 0 2 2 2 0 ROS/MUCR transcriptional regulator protein zinc_ribbon_5 PF13719.6 CDJ98341.1 - 0.039 13.7 2.3 0.53 10.1 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_11 PF16622.5 CDJ98341.1 - 0.047 13.5 0.4 0.047 13.5 0.4 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 CDJ98341.1 - 0.12 12.5 0.3 11 6.3 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 CDJ98341.1 - 0.58 10.1 2.4 6.5 6.8 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Inositol_P PF00459.25 CDJ98342.1 - 3.3e-36 125.2 0.4 9.8e-36 123.7 0.0 1.8 2 0 0 2 2 2 1 Inositol monophosphatase family Las1 PF04031.13 CDJ98342.1 - 3e-05 24.2 0.1 7.3e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Las1-like Dehydratase_LU PF02286.15 CDJ98342.1 - 0.0014 17.3 0.0 0.0022 16.7 0.0 1.1 1 0 0 1 1 1 1 Dehydratase large subunit Las1 PF04031.13 CDJ98344.1 - 5.6e-18 65.5 0.8 8.7e-18 64.9 0.8 1.3 1 0 0 1 1 1 1 Las1-like Collagen PF01391.18 CDJ98345.1 - 5e-21 74.2 68.8 3.7e-10 39.4 27.3 3.9 3 2 0 3 3 3 3 Collagen triple helix repeat (20 copies) Astacin PF01400.24 CDJ98346.1 - 1.3e-47 161.9 0.2 1.5e-47 161.7 0.2 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) DUF4804 PF16062.5 CDJ98346.1 - 0.049 12.4 0.0 0.065 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4804) Pkinase PF00069.25 CDJ98347.1 - 1.6e-59 201.4 0.0 2.7e-59 200.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ98347.1 - 1.9e-39 135.5 0.0 3.1e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1 PF00415.18 CDJ98347.1 - 1e-37 128.5 5.3 3.2e-10 40.5 0.1 6.6 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Collagen PF01391.18 CDJ98347.1 - 4.1e-20 71.3 100.1 1.8e-08 34.0 36.8 4.4 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) RCC1_2 PF13540.6 CDJ98347.1 - 2.6e-16 58.9 22.9 5.2e-06 26.1 0.0 6.7 7 0 0 7 7 6 5 Regulator of chromosome condensation (RCC1) repeat Col_cuticle_N PF01484.17 CDJ98347.1 - 4.3e-15 55.5 1.3 9.1e-15 54.5 1.3 1.5 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Kinase-like PF14531.6 CDJ98347.1 - 7.8e-10 38.5 0.0 1.3e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like SlyX PF04102.12 CDJ98347.1 - 0.00065 20.3 3.2 0.0014 19.2 3.2 1.6 1 0 0 1 1 1 1 SlyX IU_nuc_hydro PF01156.19 CDJ98347.1 - 0.00085 19.0 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF724 PF05266.14 CDJ98347.1 - 0.053 13.3 1.6 0.09 12.6 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Spc29 PF17082.5 CDJ98347.1 - 0.089 12.6 0.9 0.18 11.6 0.9 1.4 1 0 0 1 1 1 0 Spindle Pole Component 29 Spc7 PF08317.11 CDJ98347.1 - 0.32 9.8 5.2 0.49 9.2 5.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Sec2p PF06428.11 CDJ98347.1 - 0.45 10.5 6.6 0.86 9.6 6.6 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p ABC_tran_CTD PF16326.5 CDJ98347.1 - 0.82 10.0 7.5 1.1 9.5 6.2 1.8 2 0 0 2 2 1 0 ABC transporter C-terminal domain GAS PF13851.6 CDJ98347.1 - 1.7 7.9 8.1 2.9 7.2 8.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 CDJ98347.1 - 1.9 8.6 7.4 3.5 7.7 7.4 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Csm1_N PF18504.1 CDJ98347.1 - 3.3 8.1 6.6 31 5.0 4.8 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain OmpH PF03938.14 CDJ98347.1 - 6.2 7.1 7.8 14 6.0 7.8 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DOT1 PF08123.13 CDJ98349.1 - 4.1e-58 196.3 0.1 6.2e-58 195.7 0.1 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Sigma70_r2 PF04542.14 CDJ98349.1 - 0.039 13.7 0.0 4.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Sigma-70 region 2 Methyltransf_12 PF08242.12 CDJ98349.1 - 0.11 13.2 0.1 0.63 10.8 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain GatB_N PF02934.15 CDJ98349.1 - 0.31 10.4 2.5 3.5 7.0 0.0 3.0 3 1 0 3 3 3 0 GatB/GatE catalytic domain RVT_1 PF00078.27 CDJ98350.1 - 2.3e-22 79.6 0.0 4.1e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_12 PF13087.6 CDJ98352.1 - 1.4e-27 96.6 0.0 2.2e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CDJ98352.1 - 6.7e-07 29.3 0.1 0.0028 17.4 0.0 2.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 CDJ98352.1 - 0.0029 17.4 0.1 0.026 14.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain RVT_1 PF00078.27 CDJ98353.1 - 1.1e-14 54.4 0.0 2.6e-13 50.0 0.0 2.5 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_1_7 PF13843.6 CDJ98354.1 - 2.4e-56 191.6 0.5 2.7e-56 191.4 0.5 1.0 1 0 0 1 1 1 1 Transposase IS4 IGFL PF14653.6 CDJ98354.1 - 0.12 12.4 0.2 0.37 10.8 0.2 1.8 1 1 0 1 1 1 0 Insulin growth factor-like family TFIIF_alpha PF05793.12 CDJ98356.1 - 2.4e-87 293.7 28.2 2.8e-87 293.5 28.2 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CCDC106 PF15794.5 CDJ98356.1 - 2.4 7.8 15.6 0.68 9.6 8.6 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 SCO1-SenC PF02630.14 CDJ98357.1 - 5.9e-46 155.7 0.1 6.3e-45 152.4 0.0 2.0 2 0 0 2 2 2 1 SCO1/SenC AhpC-TSA PF00578.21 CDJ98357.1 - 0.0015 18.5 0.1 0.0038 17.1 0.1 1.7 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 CDJ98357.1 - 0.0045 17.3 1.3 0.027 14.8 0.0 2.8 2 1 0 2 2 2 1 Thioredoxin-like DUF2207 PF09972.9 CDJ98357.1 - 0.3 9.8 2.7 0.36 9.5 2.2 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Surp PF01805.20 CDJ98358.1 - 1.7e-40 136.7 6.5 6.6e-20 70.8 0.5 2.6 2 0 0 2 2 2 2 Surp module PRP21_like_P PF12230.8 CDJ98358.1 - 2.8e-39 135.2 5.9 4.8e-39 134.5 5.9 1.4 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein ubiquitin PF00240.23 CDJ98358.1 - 6.3e-13 48.3 0.9 1.9e-12 46.7 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 CDJ98358.1 - 7.3e-05 22.5 0.2 0.0002 21.1 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like dCache_1 PF02743.18 CDJ98359.1 - 4.7e-07 29.8 0.1 6.7e-06 26.1 0.0 2.6 2 0 0 2 2 2 1 Cache domain VWA_3 PF13768.6 CDJ98359.1 - 3.3e-06 27.1 0.0 6.7e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 CDJ98359.1 - 3.1e-05 24.3 0.0 7.4e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VGCC_alpha2 PF08473.11 CDJ98359.1 - 4.8e-05 22.3 0.2 0.0035 16.2 0.1 2.2 2 0 0 2 2 2 2 Neuronal voltage-dependent calcium channel alpha 2acd VWA_N PF08399.11 CDJ98359.1 - 0.00014 22.4 0.0 0.00026 21.5 0.0 1.5 1 0 0 1 1 1 1 VWA N-terminal VWA_2 PF13519.6 CDJ98359.1 - 0.016 15.8 0.0 0.046 14.4 0.0 1.8 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF4686 PF15742.5 CDJ98359.1 - 0.12 11.5 1.0 0.18 10.9 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) GalP_UDP_tr_C PF02744.17 CDJ98360.1 - 0.069 12.9 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain Ground-like PF04155.18 CDJ98361.1 - 2e-09 37.9 0.9 5.4e-09 36.6 0.9 1.7 1 0 0 1 1 1 1 Ground-like domain Cornifin PF02389.15 CDJ98361.1 - 0.0098 16.1 4.7 0.016 15.4 4.7 1.3 1 0 0 1 1 1 1 Cornifin (SPRR) family Hormone_recep PF00104.30 CDJ98362.1 - 3.8e-13 49.5 1.0 7.1e-13 48.6 1.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor GEMIN8 PF15348.6 CDJ98364.1 - 1.4e-22 81.1 30.3 1.6e-22 80.9 13.8 3.2 2 1 1 3 3 3 2 Gemini of Cajal bodies-associated protein 8 GKAP PF03359.13 CDJ98364.1 - 5.4e-22 78.8 8.6 5.4e-22 78.8 8.6 2.1 2 0 0 2 2 2 1 Guanylate-kinase-associated protein (GKAP) protein DUF87 PF01935.17 CDJ98364.1 - 1.9 8.5 5.5 7.3 6.6 2.4 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain PDCD2_C PF04194.13 CDJ98364.1 - 3.7 7.6 14.6 3.2 7.8 5.6 3.0 2 1 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain RPAP2_Rtr1 PF04181.13 CDJ98364.1 - 5.2 7.5 6.8 0.82 10.0 1.7 2.2 2 0 0 2 2 2 0 Rtr1/RPAP2 family DUF966 PF06136.13 CDJ98366.1 - 2.4 7.8 15.9 3 7.5 15.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) V_ATPase_I PF01496.19 CDJ98366.1 - 5.4 4.8 10.6 6.4 4.6 10.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Asp-B-Hydro_N PF05279.11 CDJ98366.1 - 8.7 6.3 17.7 11 6.0 17.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Band_7 PF01145.25 CDJ98367.1 - 6.1e-19 68.7 0.1 1.9e-18 67.1 0.1 1.8 2 0 0 2 2 2 1 SPFH domain / Band 7 family SCP2 PF02036.17 CDJ98367.1 - 6.3e-08 33.0 0.0 1.8e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 SCP-2 sterol transfer family SPATA48 PF15073.6 CDJ98367.1 - 0.087 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Spermatogenesis-associated protein 48 IF-2B PF01008.17 CDJ98368.1 - 3.6e-68 229.8 0.2 5.1e-68 229.3 0.2 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family PS_pyruv_trans PF04230.13 CDJ98368.1 - 0.056 13.4 0.0 0.087 12.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase SMN PF06003.12 CDJ98368.1 - 0.37 10.0 2.7 0.71 9.1 2.7 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) KH_1 PF00013.29 CDJ98369.1 - 2.1e-06 27.4 0.7 4.3e-06 26.4 0.7 1.6 1 0 0 1 1 1 1 KH domain Spb1_C PF07780.12 CDJ98370.1 - 3.7e-61 206.5 29.5 3.7e-61 206.5 29.5 4.7 3 1 1 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 CDJ98370.1 - 6.1e-60 202.3 0.2 1.1e-59 201.5 0.2 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 CDJ98370.1 - 2.4e-35 121.8 16.4 2.4e-35 121.8 16.4 5.2 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) Ribosomal_S27 PF01599.19 CDJ98371.1 - 1.7e-24 85.7 3.8 1.7e-24 85.7 3.8 1.7 2 0 0 2 2 2 1 Ribosomal protein S27a ubiquitin PF00240.23 CDJ98371.1 - 2.6e-12 46.3 0.1 7.6e-12 44.8 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CDJ98371.1 - 0.031 14.1 0.6 0.054 13.3 0.1 1.7 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CDJ98371.1 - 0.032 14.8 0.2 0.045 14.3 0.2 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 CDJ98371.1 - 0.045 13.7 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Nucleoplasmin PF03066.15 CDJ98371.1 - 0.1 13.1 0.1 0.17 12.4 0.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin/nucleophosmin domain ABC_tran PF00005.27 CDJ98372.1 - 1e-48 165.3 0.6 7.7e-24 84.8 0.0 3.3 3 1 1 4 4 4 2 ABC transporter ABC_tran_Xtn PF12848.7 CDJ98372.1 - 6.2e-24 83.9 3.6 6.2e-24 83.9 3.6 2.1 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CDJ98372.1 - 8.4e-12 45.5 7.9 0.0052 16.6 0.3 4.9 3 2 1 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDJ98372.1 - 5.1e-10 39.2 0.0 0.11 12.0 0.0 3.5 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDJ98372.1 - 7e-08 33.0 0.5 0.00051 20.5 0.0 3.1 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CDJ98372.1 - 2.1e-06 28.0 0.2 0.0012 19.1 0.0 3.3 4 0 0 4 4 2 1 AAA domain NACHT PF05729.12 CDJ98372.1 - 2.9e-06 27.3 0.4 0.015 15.2 0.0 3.0 3 0 0 3 3 3 2 NACHT domain AAA_15 PF13175.6 CDJ98372.1 - 3.5e-06 27.0 2.0 0.016 14.9 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_24 PF13479.6 CDJ98372.1 - 7.5e-06 25.8 0.4 0.069 12.9 0.0 3.6 4 0 0 4 4 4 2 AAA domain RsgA_GTPase PF03193.16 CDJ98372.1 - 2.9e-05 24.1 0.1 0.071 13.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MobB PF03205.14 CDJ98372.1 - 5.9e-05 23.0 0.2 0.013 15.4 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.6 CDJ98372.1 - 8.1e-05 23.2 10.5 0.0064 17.0 0.0 3.5 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CDJ98372.1 - 0.00012 21.7 0.5 0.074 12.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CDJ98372.1 - 0.00018 21.6 0.0 0.12 12.5 0.0 3.1 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA PF00004.29 CDJ98372.1 - 0.00055 20.4 0.0 0.42 11.0 0.0 3.3 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 CDJ98372.1 - 0.00076 19.7 0.1 0.26 11.5 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 CDJ98372.1 - 0.0014 18.4 1.1 0.3 10.8 0.0 3.3 3 1 0 3 3 3 1 AAA domain NB-ARC PF00931.22 CDJ98372.1 - 0.0019 17.4 0.0 1.5 7.9 0.0 2.7 2 0 0 2 2 2 2 NB-ARC domain AAA_7 PF12775.7 CDJ98372.1 - 0.003 17.1 0.1 0.44 10.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region cobW PF02492.19 CDJ98372.1 - 0.0032 17.1 0.2 0.55 9.8 0.0 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CDJ98372.1 - 0.0048 17.1 2.6 0.82 9.8 0.0 3.8 3 1 0 3 3 3 1 AAA domain AAA_28 PF13521.6 CDJ98372.1 - 0.0051 17.1 0.2 0.28 11.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain NTPase_1 PF03266.15 CDJ98372.1 - 0.006 16.5 1.3 1.4 8.9 0.0 3.1 3 0 0 3 3 3 1 NTPase AAA_14 PF13173.6 CDJ98372.1 - 0.0072 16.4 0.1 8.1 6.5 0.0 3.7 4 1 0 4 4 3 0 AAA domain Arf PF00025.21 CDJ98372.1 - 0.0073 15.8 0.1 0.99 8.8 0.0 3.3 3 0 0 3 3 3 1 ADP-ribosylation factor family RNA_helicase PF00910.22 CDJ98372.1 - 0.0091 16.4 0.1 0.82 10.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_19 PF13245.6 CDJ98372.1 - 0.011 16.0 1.6 0.13 12.5 0.0 2.9 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 CDJ98372.1 - 0.012 15.6 0.4 0.86 9.6 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 CDJ98372.1 - 0.016 14.9 0.6 4.7 6.8 0.0 3.0 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 CDJ98372.1 - 0.023 14.5 3.4 1.5 8.6 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 CDJ98372.1 - 0.028 15.0 1.4 0.73 10.4 0.3 3.2 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 CDJ98372.1 - 0.03 14.0 0.0 3.8 7.1 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SRPRB PF09439.10 CDJ98372.1 - 0.035 13.5 0.0 1.4 8.3 0.0 2.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit T2SSE PF00437.20 CDJ98372.1 - 0.066 12.3 2.3 0.28 10.2 0.1 2.9 3 1 0 3 3 3 0 Type II/IV secretion system protein Pox_A32 PF04665.12 CDJ98372.1 - 0.075 12.5 1.7 0.17 11.3 0.1 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein ATPase_2 PF01637.18 CDJ98372.1 - 0.1 12.5 0.6 6 6.7 0.0 3.2 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_13 PF13166.6 CDJ98372.1 - 0.18 10.4 8.7 2 6.9 0.0 3.7 4 0 0 4 4 4 0 AAA domain AAA_5 PF07728.14 CDJ98372.1 - 0.47 10.4 4.6 1.8 8.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) dNK PF01712.19 CDJ98372.1 - 0.48 10.2 3.2 0.68 9.7 0.0 2.7 3 0 0 3 3 3 0 Deoxynucleoside kinase DUF87 PF01935.17 CDJ98372.1 - 3.2 7.8 12.3 0.49 10.5 0.1 3.8 3 1 1 4 4 4 0 Helicase HerA, central domain Thioredoxin PF00085.20 CDJ98373.1 - 7.3e-08 32.3 0.0 1.4e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 CDJ98373.1 - 1.5e-05 24.1 0.8 1.9e-05 23.8 0.8 1.1 1 0 0 1 1 1 1 Phosducin DUF4208 PF13907.6 CDJ98373.1 - 0.037 14.4 0.4 0.07 13.6 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) Vps16_N PF04841.13 CDJ98374.1 - 7.4e-66 222.6 0.0 9.9e-66 222.2 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 CDJ98374.1 - 1.1e-25 90.4 8.1 1.1e-25 90.4 8.1 1.9 2 1 0 2 2 2 1 Vps16, C-terminal region Clathrin PF00637.20 CDJ98374.1 - 4.2e-08 33.2 1.9 9.7e-07 28.8 0.3 3.6 3 1 0 4 4 4 1 Region in Clathrin and VPS WD40_3 PF15911.5 CDJ98374.1 - 0.0069 16.4 0.0 4 7.5 0.0 2.6 1 1 1 2 2 2 2 WD domain, G-beta repeat Pdase_M17_N2 PF18295.1 CDJ98374.1 - 0.015 15.6 0.8 0.13 12.5 0.2 2.4 2 0 0 2 2 2 0 M17 aminopeptidase N-terminal domain 2 Peptidase_M16_C PF05193.21 CDJ98375.1 - 2.6e-28 99.3 0.1 1.6e-20 73.9 0.0 3.5 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CDJ98375.1 - 1.4e-09 38.1 0.0 6.3e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Nuf2 PF03800.14 CDJ98375.1 - 0.13 12.3 0.1 0.5 10.5 0.0 2.0 2 0 0 2 2 2 0 Nuf2 family M16C_assoc PF08367.11 CDJ98375.1 - 0.39 9.8 3.0 1.3 8.1 3.0 1.9 1 1 0 1 1 1 0 Peptidase M16C associated DUF2205 PF10224.9 CDJ98375.1 - 0.96 9.5 3.4 1.4 9.0 1.1 2.4 3 0 0 3 3 3 0 Short coiled-coil protein SCVP PF17619.2 CDJ98376.1 - 1.5e-27 96.3 0.4 2.4e-27 95.6 0.4 1.3 1 0 0 1 1 1 1 Secreted clade V proteins FA_FANCE PF11510.8 CDJ98376.1 - 0.05 12.9 0.0 0.06 12.7 0.0 1.0 1 0 0 1 1 1 0 Fanconi Anaemia group E protein FANCE RRM_1 PF00076.22 CDJ98378.1 - 2.9e-23 81.5 0.0 6.5e-12 45.1 0.0 3.9 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ98378.1 - 7.9e-07 29.1 0.3 0.056 13.6 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif SF3A2 PF16835.5 CDJ98379.1 - 1.3e-39 134.4 0.5 2.6e-39 133.5 0.2 1.6 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) CactinC_cactus PF09732.9 CDJ98379.1 - 7.6e-05 22.6 0.2 0.00012 22.0 0.2 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cpn60_TCP1 PF00118.24 CDJ98380.1 - 1.8e-128 429.3 2.1 7.9e-122 407.4 0.2 2.1 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family bZIP_1 PF00170.21 CDJ98380.1 - 1.1e-05 25.4 5.8 3e-05 24.0 5.8 1.7 1 0 0 1 1 1 1 bZIP transcription factor NTP_transf_5 PF14907.6 CDJ98380.1 - 1.3e-05 24.9 0.2 3e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 Uncharacterised nucleotidyltransferase bZIP_2 PF07716.15 CDJ98380.1 - 0.00026 21.0 9.0 0.00072 19.6 9.0 1.7 1 0 0 1 1 1 1 Basic region leucine zipper 5_3_exonuc PF01367.20 CDJ98380.1 - 0.047 14.3 0.4 16 6.2 0.1 3.1 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF5320 PF17253.2 CDJ98380.1 - 0.087 13.9 0.2 0.25 12.4 0.2 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5320) bZIP_Maf PF03131.17 CDJ98380.1 - 0.1 13.1 4.9 0.29 11.7 4.9 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor Cnn_1N PF07989.11 CDJ98380.1 - 0.25 11.5 2.8 0.74 10.0 2.8 1.8 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Mtp PF03821.16 CDJ98381.1 - 0.019 14.6 4.8 0.04 13.5 0.9 2.3 1 1 1 2 2 2 0 Golgi 4-transmembrane spanning transporter Acyl_transf_3 PF01757.22 CDJ98381.1 - 0.021 13.9 7.1 0.027 13.5 7.1 1.1 1 0 0 1 1 1 0 Acyltransferase family SLAC1 PF03595.17 CDJ98381.1 - 0.04 13.2 8.6 0.57 9.4 2.5 2.0 1 1 1 2 2 2 0 Voltage-dependent anion channel PHO4 PF01384.20 CDJ98381.1 - 0.2 10.7 3.8 0.26 10.3 3.8 1.3 1 0 0 1 1 1 0 Phosphate transporter family COX7a PF02238.15 CDJ98381.1 - 0.32 11.4 2.9 9.2 6.8 0.4 3.0 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VII TcpE PF12648.7 CDJ98381.1 - 5.2 7.7 9.4 0.99 10.0 2.9 2.4 1 1 1 2 2 2 0 TcpE family BTB PF00651.31 CDJ98382.1 - 1.2e-20 73.7 0.7 3.5e-20 72.3 0.5 1.9 1 1 1 2 2 2 1 BTB/POZ domain SAPS PF04499.15 CDJ98382.1 - 0.069 11.9 0.1 0.18 10.5 0.0 1.6 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein PP2C PF00481.21 CDJ98383.1 - 4.4e-53 180.5 0.0 6.4e-53 180.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CDJ98383.1 - 0.0041 16.8 0.0 0.2 11.2 0.0 2.7 2 1 1 3 3 3 1 Protein phosphatase 2C DSPc PF00782.20 CDJ98384.1 - 3.2e-32 111.1 0.0 1.9e-31 108.6 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDJ98384.1 - 0.00025 20.7 0.0 0.0004 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Glyco_hydro_108 PF05838.12 CDJ98384.1 - 0.076 13.5 0.0 0.79 10.2 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase 108 PTPlike_phytase PF14566.6 CDJ98384.1 - 0.14 12.3 0.1 0.32 11.1 0.0 1.6 2 0 0 2 2 2 0 Inositol hexakisphosphate Pkinase PF00069.25 CDJ98385.1 - 1.4e-57 195.1 0.0 1.6e-57 194.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ98385.1 - 3.8e-35 121.4 0.0 4.8e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ98385.1 - 0.00076 18.5 0.8 0.001 18.1 0.8 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CDJ98385.1 - 0.0031 16.3 0.0 0.0057 15.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDJ98385.1 - 0.045 13.1 0.0 0.098 12.0 0.0 1.7 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 CDJ98385.1 - 0.1 12.5 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RPA_interact_C PF14768.6 CDJ98387.1 - 5.5e-08 33.3 2.7 5.5e-08 33.3 2.7 1.6 2 0 0 2 2 2 1 Replication protein A interacting C-terminal RPA_interact_N PF14766.6 CDJ98387.1 - 4.9e-05 22.9 5.4 0.00019 21.0 5.5 1.9 2 0 0 2 2 2 1 Replication protein A interacting N-terminal Zn_Tnp_IS1595 PF12760.7 CDJ98387.1 - 0.0091 16.0 1.5 2.4 8.2 0.2 2.5 2 0 0 2 2 2 2 Transposase zinc-ribbon domain IBR PF01485.21 CDJ98387.1 - 0.076 13.3 0.9 1.6 9.0 0.1 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zinc_ribbon_4 PF13717.6 CDJ98387.1 - 0.076 13.0 4.0 11 6.1 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain eIF-5_eIF-2B PF01873.17 CDJ98387.1 - 0.1 12.4 1.1 1 9.2 0.0 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 NleF_casp_inhib PF16809.5 CDJ98387.1 - 0.14 12.1 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 NleF caspase inhibitor GP67 PF17634.2 CDJ98388.1 - 0.02 15.3 8.4 0.38 11.2 2.2 2.3 2 0 0 2 2 2 0 Gene product 67 TEX19 PF15553.6 CDJ98388.1 - 1.3 9.0 5.9 0.22 11.5 0.7 2.1 1 1 1 2 2 2 0 Testis-expressed protein 19 DUF4337 PF14235.6 CDJ98388.1 - 7.5 6.6 6.3 7.5 6.6 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) PPL5 PF18168.1 CDJ98388.1 - 7.9 5.7 9.3 0.57 9.4 0.9 2.4 2 0 0 2 2 2 0 Prim-pol family 5 DUF601 PF04642.12 CDJ98389.1 - 0.044 13.3 9.8 0.05 13.1 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Macoilin PF09726.9 CDJ98389.1 - 0.16 10.5 6.6 0.17 10.4 6.6 1.1 1 0 0 1 1 1 0 Macoilin family Vfa1 PF08432.10 CDJ98389.1 - 0.94 9.8 11.1 1.2 9.4 11.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NAD_binding_10 PF13460.6 CDJ98390.1 - 3.2e-16 59.8 0.0 4.4e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 CDJ98390.1 - 5.6e-07 30.0 0.1 8.8e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain HIM1 PF08732.10 CDJ98390.1 - 5.6e-06 26.0 0.0 7.7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 HIM1 Epimerase PF01370.21 CDJ98390.1 - 1.8e-05 24.3 0.1 0.00014 21.4 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CDJ98390.1 - 0.0049 15.9 0.3 0.0073 15.3 0.3 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 CDJ98390.1 - 0.0081 16.3 0.1 0.017 15.2 0.1 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus ACP_syn_III PF08545.10 CDJ98390.1 - 0.0087 15.9 0.1 0.59 10.0 0.0 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Polysacc_synt_2 PF02719.15 CDJ98390.1 - 0.014 14.5 0.0 0.074 12.2 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NmrA PF05368.13 CDJ98390.1 - 0.014 14.9 0.7 0.051 13.1 0.4 2.0 1 1 1 2 2 2 0 NmrA-like family KR PF08659.10 CDJ98390.1 - 0.052 13.5 0.0 0.48 10.3 0.0 2.2 3 0 0 3 3 3 0 KR domain Sacchrp_dh_NADP PF03435.18 CDJ98390.1 - 0.1 12.8 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PH_16 PF17838.1 CDJ98391.1 - 1.3e-12 47.7 0.0 3.4e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.20 CDJ98391.1 - 8.4e-10 39.2 1.2 2.5e-09 37.6 0.1 2.3 3 0 0 3 3 3 1 RhoGEF domain Macoilin PF09726.9 CDJ98391.1 - 0.00012 20.8 13.2 0.00012 20.8 13.2 1.9 1 1 1 2 2 2 1 Macoilin family HMMR_C PF15908.5 CDJ98391.1 - 0.0061 16.8 0.5 0.0061 16.8 0.5 3.7 3 1 1 4 4 4 1 Hyaluronan mediated motility receptor C-terminal TMEM119 PF15724.5 CDJ98391.1 - 1.6 8.8 3.7 3.7 7.5 3.7 1.5 1 0 0 1 1 1 0 TMEM119 family ER PF01133.17 CDJ98392.1 - 4.6e-42 142.0 0.4 5.4e-42 141.8 0.4 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary ComFB PF10719.9 CDJ98392.1 - 0.085 13.0 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Late competence development protein ComFB GYF_2 PF14237.6 CDJ98393.1 - 9.1e-16 57.4 0.2 2.1e-15 56.2 0.2 1.7 1 0 0 1 1 1 1 GYF domain 2 DnaJ PF00226.31 CDJ98393.1 - 4.4e-12 46.0 0.0 9.9e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Myosin_TH1 PF06017.13 CDJ98393.1 - 0.015 15.0 0.0 0.048 13.3 0.0 1.8 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding Arm_2 PF04826.13 CDJ98393.1 - 0.046 13.2 7.3 0.13 11.7 1.3 3.3 3 0 0 3 3 3 0 Armadillo-like MMS19_C PF12460.8 CDJ98393.1 - 1.2 8.1 6.0 13 4.8 0.1 3.5 4 0 0 4 4 4 0 RNAPII transcription regulator C-terminal Ldl_recept_a PF00057.18 CDJ98395.1 - 4e-08 33.3 4.2 9.7e-08 32.1 4.2 1.7 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A CUB PF00431.20 CDJ98395.1 - 8.5e-08 32.5 0.0 3e-06 27.5 0.0 2.2 1 1 0 1 1 1 1 CUB domain Kinesin PF00225.23 CDJ98396.1 - 1e-115 386.2 0.0 1.9e-115 385.3 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ98396.1 - 1.5e-24 86.7 0.1 2.3e-23 82.8 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding AAA_30 PF13604.6 CDJ98396.1 - 0.003 17.3 0.1 0.022 14.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Kinesin_assoc PF16183.5 CDJ98396.1 - 0.0056 16.9 7.6 0.059 13.5 7.1 2.7 2 1 0 2 2 2 1 Kinesin-associated DivIC PF04977.15 CDJ98396.1 - 0.012 15.4 2.1 0.012 15.4 2.1 4.3 2 1 1 4 4 4 0 Septum formation initiator NACHT PF05729.12 CDJ98396.1 - 0.014 15.3 1.2 0.32 10.9 0.0 2.7 2 0 0 2 2 2 0 NACHT domain PYNP_C PF07831.13 CDJ98396.1 - 0.041 13.5 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain Flagellin_C PF00700.21 CDJ98396.1 - 0.9 9.9 5.0 0.81 10.1 0.1 3.0 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region AAA_16 PF13191.6 CDJ98396.1 - 1.4 9.3 0.0 1.4 9.3 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain DUF16 PF01519.16 CDJ98396.1 - 7.2 7.2 14.5 31 5.1 8.3 2.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 Carn_acyltransf PF00755.20 CDJ98397.1 - 6.5e-177 589.7 0.0 7.4e-177 589.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase FAD_binding_3 PF01494.19 CDJ98397.1 - 0.1 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Vps35 PF03635.17 CDJ98399.1 - 3e-240 799.7 1.8 4.3e-240 799.1 1.8 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Glyco_transf_21 PF13506.6 CDJ98399.1 - 2.2e-48 164.0 0.0 3.6e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 CDJ98399.1 - 2.1e-20 73.6 0.0 4.7e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CDJ98399.1 - 1.8e-11 44.3 1.9 1.8e-11 44.3 1.9 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Smg8_Smg9 PF10220.9 CDJ98401.1 - 0.0085 14.5 3.4 0.0097 14.3 3.4 1.0 1 0 0 1 1 1 1 Smg8_Smg9 Apt1 PF10351.9 CDJ98401.1 - 0.079 11.8 4.4 0.096 11.5 4.4 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain SURF2 PF05477.11 CDJ98401.1 - 4.5 6.9 8.2 5.8 6.5 8.2 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CDC45 PF02724.14 CDJ98401.1 - 6.8 4.9 11.3 7.3 4.8 11.3 1.1 1 0 0 1 1 1 0 CDC45-like protein p450 PF00067.22 CDJ98403.1 - 9.4e-78 262.0 0.0 1.1e-77 261.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Astacin PF01400.24 CDJ98404.1 - 3.2e-52 176.9 0.3 8.2e-52 175.6 0.3 1.7 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 CDJ98404.1 - 0.00017 21.3 0.2 0.00037 20.2 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CDJ98404.1 - 0.0019 18.1 2.1 0.011 15.5 2.1 2.0 1 1 0 1 1 1 1 Matrixin CUB PF00431.20 CDJ98404.1 - 0.0096 16.3 0.2 0.02 15.3 0.2 1.5 1 0 0 1 1 1 1 CUB domain Reprolysin_3 PF13582.6 CDJ98404.1 - 0.012 16.1 0.2 0.035 14.6 0.2 1.9 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 CDJ98404.1 - 0.022 14.0 0.2 0.044 13.0 0.2 1.4 1 0 0 1 1 1 0 Met-zincin Reprolysin_5 PF13688.6 CDJ98404.1 - 0.023 14.9 0.2 0.061 13.5 0.2 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12 EGF_2 PF07974.13 CDJ98404.1 - 0.25 11.8 10.7 0.5 10.8 10.7 1.6 1 0 0 1 1 1 0 EGF-like domain CDK2AP PF09806.9 CDJ98405.1 - 1.4e-20 74.4 0.0 1.5e-20 74.3 0.0 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein Hema_stalk PF08720.10 CDJ98405.1 - 0.038 13.7 0.0 0.041 13.6 0.0 1.1 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk KH_1 PF00013.29 CDJ98406.1 - 3.8e-20 71.5 0.7 1.4e-09 37.6 0.3 3.0 3 0 0 3 3 3 2 KH domain SLS PF14611.6 CDJ98406.1 - 0.0087 15.9 0.1 0.75 9.6 0.0 2.7 2 1 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 CDJ98406.1 - 0.01 15.7 0.2 0.56 10.1 0.1 2.4 2 0 0 2 2 2 0 KH domain Dimerisation PF08100.11 CDJ98406.1 - 0.072 13.1 0.0 0.25 11.4 0.0 1.9 1 0 0 1 1 1 0 Dimerisation domain NRDE-2 PF08424.10 CDJ98406.1 - 0.1 11.7 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference KH_4 PF13083.6 CDJ98406.1 - 0.14 12.1 0.4 0.95 9.4 0.0 2.5 3 0 0 3 3 3 0 KH domain LSM PF01423.22 CDJ98407.1 - 8.8e-16 57.4 0.0 1.1e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CDJ98407.1 - 0.0016 18.6 0.1 0.0021 18.2 0.1 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain Rgp1 PF08737.10 CDJ98408.1 - 1.6e-36 126.4 0.0 5.5e-24 85.1 0.0 2.3 1 1 1 2 2 2 2 Rgp1 WD40_like PF17005.5 CDJ98409.1 - 4.9e-06 26.1 0.0 5.3e-05 22.7 0.0 2.3 2 1 1 3 3 3 1 WD40-like domain WD40 PF00400.32 CDJ98409.1 - 0.002 18.9 8.4 1.5 9.8 0.0 4.9 3 1 1 4 4 4 2 WD domain, G-beta repeat CDK2AP PF09806.9 CDJ98410.1 - 1.4e-20 74.4 0.0 1.5e-20 74.3 0.0 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein Hema_stalk PF08720.10 CDJ98410.1 - 0.038 13.7 0.0 0.041 13.6 0.0 1.1 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk HMA PF00403.26 CDJ98411.1 - 4.3e-10 39.9 2.4 6.4e-10 39.3 2.4 1.3 1 1 0 1 1 1 1 Heavy-metal-associated domain UTP25 PF06862.12 CDJ98412.1 - 1.7e-111 373.3 0.4 2.5e-111 372.8 0.4 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF3105 PF11303.8 CDJ98412.1 - 6.4e-38 129.8 0.0 1.5e-37 128.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3105) ADK PF00406.22 CDJ98414.1 - 3.6e-33 114.8 0.0 4.8e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CDJ98414.1 - 6.5e-15 55.8 0.2 2e-14 54.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 CDJ98414.1 - 3.4e-14 52.5 0.0 8.6e-14 51.2 0.0 1.7 2 0 0 2 2 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 CDJ98414.1 - 3.1e-08 34.2 0.0 1.1e-07 32.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ98414.1 - 0.00081 19.8 0.0 0.0027 18.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 CDJ98414.1 - 0.0022 17.9 0.0 0.0053 16.7 0.0 1.7 2 0 0 2 2 2 1 Adenylylsulphate kinase Cytidylate_kin PF02224.18 CDJ98414.1 - 0.007 16.1 0.0 0.0089 15.8 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase AAA_33 PF13671.6 CDJ98414.1 - 0.0074 16.5 0.0 0.016 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain Guanylate_kin PF00625.21 CDJ98414.1 - 0.0091 15.7 0.0 0.016 14.9 0.0 1.5 2 0 0 2 2 2 1 Guanylate kinase ABC_tran PF00005.27 CDJ98414.1 - 0.012 16.1 0.0 0.016 15.7 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 CDJ98414.1 - 0.012 15.8 0.0 0.067 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CDJ98414.1 - 0.014 15.8 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CDJ98414.1 - 0.054 12.5 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.15 CDJ98414.1 - 0.062 13.2 0.0 0.14 12.0 0.0 1.8 1 1 0 1 1 1 0 NTPase Thymidylate_kin PF02223.17 CDJ98414.1 - 0.068 12.8 0.0 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 Thymidylate kinase NB-ARC PF00931.22 CDJ98414.1 - 0.093 11.9 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RuvB_N PF05496.12 CDJ98414.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CDJ98414.1 - 0.11 12.5 0.1 0.17 11.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 CDJ98414.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_7 PF12775.7 CDJ98414.1 - 0.17 11.3 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ADK PF00406.22 CDJ98415.1 - 1.8e-18 67.1 0.0 2.5e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.14 CDJ98415.1 - 2.8e-15 56.0 0.0 5.1e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 CDJ98415.1 - 0.0064 17.0 0.0 0.013 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF761 PF05553.11 CDJ98417.1 - 0.13 11.9 0.3 0.29 10.7 0.3 1.5 1 0 0 1 1 1 0 Cotton fibre expressed protein Pkinase PF00069.25 CDJ98418.1 - 2.9e-56 190.8 0.0 5.2e-56 189.9 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ98418.1 - 6.4e-22 78.1 0.0 8.9e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ98418.1 - 0.0001 22.3 0.1 0.00018 21.5 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ98418.1 - 0.0028 17.0 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Nop14 PF04147.12 CDJ98418.1 - 1.2 7.3 6.3 1.6 6.9 6.3 1.1 1 0 0 1 1 1 0 Nop14-like family zf-BED PF02892.15 CDJ98420.1 - 1.2e-09 38.0 5.1 0.0005 20.0 0.4 2.5 2 0 0 2 2 2 2 BED zinc finger EPL1 PF10513.9 CDJ98420.1 - 0.0075 16.7 4.2 0.0075 16.7 4.2 2.1 2 0 0 2 2 1 1 Enhancer of polycomb-like MecA PF05389.12 CDJ98420.1 - 0.0089 15.7 7.9 0.025 14.2 7.9 1.8 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) UPF0560 PF10577.9 CDJ98420.1 - 0.056 12.0 19.9 0.11 11.0 19.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CTU2 PF10288.9 CDJ98420.1 - 0.065 13.5 11.9 0.1 12.9 9.7 2.6 2 0 0 2 2 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Peptidase_S49_N PF08496.10 CDJ98420.1 - 0.065 13.3 10.7 0.15 12.1 10.7 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FPN1 PF06963.12 CDJ98420.1 - 0.097 11.2 3.0 0.15 10.6 3.0 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF853 PF05872.12 CDJ98420.1 - 0.14 10.7 9.4 0.22 10.1 9.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) SpoIIP PF07454.11 CDJ98420.1 - 0.16 11.4 9.2 0.43 10.0 9.2 1.6 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) AAA_23 PF13476.6 CDJ98420.1 - 0.25 11.8 16.0 0.34 11.4 14.8 1.9 2 0 0 2 2 1 0 AAA domain MAJIN PF15077.6 CDJ98420.1 - 0.34 10.7 7.4 0.9 9.3 7.4 1.7 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF2052 PF09747.9 CDJ98420.1 - 0.41 10.7 12.4 0.14 12.3 7.2 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 CDJ98420.1 - 0.57 10.0 15.6 0.068 13.0 10.5 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Peroxin-13_N PF04088.13 CDJ98420.1 - 0.81 10.0 6.6 2.3 8.5 6.6 1.7 1 0 0 1 1 1 0 Peroxin 13, N-terminal region zf-C2H2_4 PF13894.6 CDJ98420.1 - 0.83 10.7 10.3 4 8.5 2.7 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger EIIBC-GUT_N PF03612.14 CDJ98420.1 - 1 9.1 9.1 3.6 7.3 9.3 1.8 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Exonuc_VII_L PF02601.15 CDJ98420.1 - 1.4 8.4 18.1 3 7.3 18.1 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit Endonuc_Holl PF10107.9 CDJ98420.1 - 1.5 8.7 6.9 3 7.7 6.9 1.5 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase zf-H2C2_5 PF13909.6 CDJ98420.1 - 1.7 8.5 12.9 5.3 6.9 4.8 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain MCU PF04678.13 CDJ98420.1 - 1.7 8.7 8.2 4.4 7.4 8.2 1.7 1 0 0 1 1 1 0 Mitochondrial calcium uniporter V_ATPase_I PF01496.19 CDJ98420.1 - 1.8 6.4 12.0 2.6 5.8 12.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Dynactin_p62 PF05502.13 CDJ98420.1 - 2 7.1 16.3 3.9 6.1 16.3 1.4 1 0 0 1 1 1 0 Dynactin p62 family Muted PF14942.6 CDJ98420.1 - 2.1 8.7 16.5 5.7 7.3 16.5 1.7 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein ALMT PF11744.8 CDJ98420.1 - 2.3 7.0 12.5 4.1 6.1 12.5 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter FTO_NTD PF12933.7 CDJ98420.1 - 2.5 7.2 11.2 5.9 6.0 11.2 1.5 1 0 0 1 1 1 0 FTO catalytic domain SID-1_RNA_chan PF13965.6 CDJ98420.1 - 2.6 6.3 5.0 3.8 5.8 5.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Rxt3 PF08642.10 CDJ98420.1 - 2.6 8.8 5.6 9.5 7.0 5.6 2.0 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 PepSY_TM PF03929.16 CDJ98420.1 - 3.9 7.1 8.2 11 5.6 8.2 1.7 1 0 0 1 1 1 0 PepSY-associated TM region Folliculin PF11704.8 CDJ98420.1 - 4.7 7.1 14.0 18 5.2 14.0 2.0 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Connexin PF00029.19 CDJ98420.1 - 5.1 6.8 5.9 8.6 6.0 5.9 1.3 1 0 0 1 1 1 0 Connexin Membralin PF09746.9 CDJ98420.1 - 6 5.8 7.3 10 5.0 7.3 1.3 1 0 0 1 1 1 0 Tumour-associated protein Serinc PF03348.15 CDJ98420.1 - 6.5 5.6 5.1 9.9 5.0 5.1 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Bud13 PF09736.9 CDJ98420.1 - 7.7 6.9 18.2 14 6.1 16.1 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Activator_LAG-3 PF11498.8 CDJ98420.1 - 9 5.1 53.2 16 4.3 53.2 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SNF PF00209.18 CDJ98421.1 - 6.3e-72 242.9 8.8 1.7e-70 238.2 8.8 2.0 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Brr6_like_C_C PF10104.9 CDJ98421.1 - 0.0044 16.8 0.1 0.0044 16.8 0.1 1.6 2 0 0 2 2 2 1 Di-sulfide bridge nucleocytoplasmic transport domain Oleosin PF01277.17 CDJ98421.1 - 0.34 10.7 2.3 9.8 6.0 0.2 2.9 2 1 1 3 3 3 0 Oleosin VirB3 PF05101.13 CDJ98421.1 - 0.38 11.0 6.1 1.6 9.0 0.1 2.4 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein MANEC PF07502.14 CDJ98422.1 - 0.63 10.3 5.7 0.96 9.8 1.6 2.4 2 1 0 2 2 2 0 MANEC domain Geminin PF07412.12 CDJ98424.1 - 0.0014 18.4 3.5 0.0025 17.6 3.5 1.5 1 1 0 1 1 1 1 Geminin Collagen PF01391.18 CDJ98426.1 - 1.9e-44 149.3 193.3 5.3e-10 38.9 37.8 6.4 4 2 1 5 5 5 5 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ98426.1 - 8.7e-07 28.9 0.2 1.2e-06 28.5 0.2 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain CNDH2_C PF16858.5 CDJ98427.1 - 0.068 13.0 10.8 0.15 11.9 10.5 1.6 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term AATF-Che1 PF13339.6 CDJ98427.1 - 0.78 10.4 10.4 22 5.7 9.0 2.7 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor CorA PF01544.18 CDJ98427.1 - 0.83 8.9 7.6 0.78 9.0 6.0 1.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Allexi_40kDa PF05549.11 CDJ98427.1 - 1.2 8.6 6.6 1.1 8.7 3.8 2.2 1 1 2 3 3 3 0 Allexivirus 40kDa protein DUF4140 PF13600.6 CDJ98427.1 - 1.4 9.4 6.6 7.4 7.1 2.0 2.9 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) NYD-SP28_assoc PF14775.6 CDJ98427.1 - 5.7 7.1 7.4 15 5.8 1.1 3.3 3 1 0 3 3 3 0 Sperm tail C-terminal domain DUF4407 PF14362.6 CDJ98427.1 - 6.2 6.1 12.5 33 3.7 12.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) 7TM_GPCR_Srab PF10292.9 CDJ98428.1 - 1.3e-21 76.9 5.0 1.4e-21 76.7 5.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Sra PF02117.16 CDJ98428.1 - 3.3e-19 68.9 5.3 3.5e-19 68.8 5.3 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sra Sre PF03125.18 CDJ98428.1 - 1.4e-09 37.6 16.2 5.7e-08 32.3 16.2 2.8 1 1 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor 7TM_GPCR_Srb PF02175.16 CDJ98428.1 - 7.2e-07 29.2 1.0 1.5e-06 28.1 0.2 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srb DUF1772 PF08592.11 CDJ98428.1 - 0.0017 18.7 0.1 0.049 14.0 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF1772) Tmemb_185A PF10269.9 CDJ98428.1 - 0.029 14.0 3.3 0.34 10.5 0.9 2.1 2 0 0 2 2 2 0 Transmembrane Fragile-X-F protein DUF202 PF02656.15 CDJ98428.1 - 1.2 9.6 0.0 1.2 9.6 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) PHO4 PF01384.20 CDJ98428.1 - 4.1 6.4 5.8 5.3 6.0 1.8 2.0 1 1 1 2 2 2 0 Phosphate transporter family Neur_chan_LBD PF02931.23 CDJ98430.1 - 5.7e-46 156.7 0.3 8.2e-46 156.2 0.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDJ98430.1 - 5.5e-24 85.5 3.0 1.9e-22 80.5 3.0 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region PNMA PF14893.6 CDJ98431.1 - 0.00059 19.3 1.0 0.0011 18.4 1.0 1.4 1 0 0 1 1 1 1 PNMA AAA_30 PF13604.6 CDJ98431.1 - 0.01 15.5 0.0 0.026 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 CDJ98431.1 - 0.022 14.6 0.1 0.044 13.6 0.1 1.5 1 0 0 1 1 1 0 Helicase Retrotrans_gag PF03732.17 CDJ98431.1 - 0.022 15.0 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein SCAN PF02023.17 CDJ98431.1 - 0.05 13.4 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 SCAN domain ResIII PF04851.15 CDJ98431.1 - 0.085 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit adh_short PF00106.25 CDJ98432.1 - 1.9e-37 128.7 0.0 2.2e-36 125.2 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ98432.1 - 2e-22 79.9 0.0 1e-21 77.6 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ98432.1 - 9e-06 25.7 0.0 1.8e-05 24.7 0.0 1.4 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 CDJ98432.1 - 0.00017 21.1 0.0 0.00029 20.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 CDJ98432.1 - 0.0044 16.4 0.0 0.0086 15.5 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 CDJ98432.1 - 0.012 14.9 0.0 0.24 10.7 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 CDJ98432.1 - 0.043 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H-binding Claudin_2 PF13903.6 CDJ98433.1 - 0.035 13.8 5.3 0.1 12.3 5.3 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Nse5 PF08691.10 CDJ98433.1 - 0.096 11.3 0.2 0.11 11.1 0.2 1.1 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 LptF_LptG PF03739.14 CDJ98433.1 - 0.62 8.9 7.6 1.1 8.1 7.6 1.5 1 1 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG CAP PF00188.26 CDJ98435.1 - 8.3e-11 42.8 6.6 1.1e-10 42.4 6.6 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Ribosom_S12_S23 PF00164.25 CDJ98437.1 - 2.7e-21 75.3 0.2 3.2e-21 75.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 NTP_transf_2 PF01909.23 CDJ98438.1 - 0.0034 17.6 0.0 0.012 15.9 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 CDJ98438.1 - 0.1 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CDJ98439.1 - 6.6e-05 23.1 0.0 0.00015 22.0 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4269 PF14091.6 CDJ98439.1 - 0.0049 17.1 0.0 0.0096 16.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4269) Polbeta PF18765.1 CDJ98439.1 - 0.0057 16.7 0.1 0.028 14.5 0.0 2.2 1 1 1 2 2 2 1 Polymerase beta, Nucleotidyltransferase Peptidase_M30 PF10460.9 CDJ98439.1 - 0.093 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase M30 Med24_N PF11277.8 CDJ98440.1 - 4e-34 117.9 16.5 5.2e-34 117.5 16.5 1.1 1 0 0 1 1 1 1 Mediator complex subunit 24 N-terminal Ground-like PF04155.18 CDJ98441.1 - 5.6e-11 42.9 0.8 7.4e-11 42.5 0.8 1.2 1 0 0 1 1 1 1 Ground-like domain PTRF_SDPR PF15237.6 CDJ98442.1 - 0.017 14.8 1.3 0.034 13.8 1.4 1.6 1 1 0 1 1 1 0 PTRF/SDPR family Colicin PF01024.19 CDJ98442.1 - 0.036 14.0 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 Colicin pore forming domain Aa_trans PF01490.18 CDJ98443.1 - 1.1e-33 116.6 4.6 1.1e-33 116.6 4.6 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein DUF4229 PF14012.6 CDJ98443.1 - 0.078 13.1 6.0 0.057 13.5 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Aa_trans PF01490.18 CDJ98444.1 - 1.8e-28 99.4 12.5 3.6e-15 55.6 0.7 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein FF PF01846.19 CDJ98446.1 - 1.4e-63 210.8 38.7 2.4e-14 53.2 3.5 6.6 6 0 0 6 6 6 6 FF domain WW PF00397.26 CDJ98446.1 - 5.2e-24 84.0 24.7 3.5e-08 33.4 1.3 3.9 3 0 0 3 3 3 3 WW domain RhoGAP-FF1 PF16512.5 CDJ98446.1 - 2.9e-05 24.7 19.0 0.0027 18.3 1.0 4.1 3 1 1 4 4 4 2 p190-A and -B Rho GAPs FF domain Alg6_Alg8 PF03155.15 CDJ98447.1 - 2.4e-137 458.8 43.3 3.2e-137 458.4 43.3 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Endonuclease_5 PF04493.14 CDJ98447.1 - 9.5e-38 129.9 0.0 1.7e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease V Glyco_hydro_25 PF01183.20 CDJ98449.1 - 8e-05 22.9 0.2 0.0001 22.6 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Leuk-A4-hydro_C PF09127.11 CDJ98450.1 - 0.16 12.0 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal Glyco_hydro_25 PF01183.20 CDJ98451.1 - 8.9e-06 26.0 12.8 0.008 16.4 3.4 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 25 Leuk-A4-hydro_C PF09127.11 CDJ98451.1 - 0.00092 19.3 0.1 1.5 8.9 0.0 2.4 2 0 0 2 2 2 2 Leukotriene A4 hydrolase, C-terminal PUD PF03714.14 CDJ98451.1 - 0.0015 19.3 3.5 0.93 10.4 0.3 2.5 2 0 0 2 2 2 2 Bacterial pullanase-associated domain Hexokinase_2 PF03727.16 CDJ98451.1 - 0.092 12.2 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Hexokinase DUF1906 PF08924.11 CDJ98452.1 - 0.013 15.6 0.4 0.015 15.4 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1906) Leuk-A4-hydro_C PF09127.11 CDJ98452.1 - 0.13 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal Glyco_hydro_25 PF01183.20 CDJ98453.1 - 9.6e-06 25.9 1.9 1.3e-05 25.5 1.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 YppG PF14179.6 CDJ98455.1 - 2.6 8.8 7.4 3 8.6 6.6 1.5 1 1 1 2 2 2 0 YppG-like protein Zip PF02535.22 CDJ98457.1 - 3.4 6.8 4.3 4 6.6 4.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter 1-cysPrx_C PF10417.9 CDJ98458.1 - 2.7 7.9 0.0 2.7 7.9 0.0 3.4 4 0 0 4 4 4 0 C-terminal domain of 1-Cys peroxiredoxin WD40 PF00400.32 CDJ98459.1 - 3.7e-12 46.6 10.9 0.23 12.4 0.4 6.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ98459.1 - 0.00017 21.8 0.2 0.053 13.8 0.2 3.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 CDJ98459.1 - 0.041 12.8 0.1 0.094 11.6 0.1 1.5 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain ABC_tran PF00005.27 CDJ98460.1 - 1.6e-50 171.2 0.1 4e-28 98.6 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CDJ98460.1 - 6.1e-46 157.1 37.8 4.4e-33 114.8 18.3 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 CDJ98460.1 - 1.3e-20 74.5 0.6 1.5e-06 28.3 0.0 4.5 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDJ98460.1 - 1.4e-05 24.7 0.2 1.7 8.0 0.0 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CDJ98460.1 - 0.00022 21.8 9.2 0.082 13.4 0.2 2.9 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 CDJ98460.1 - 0.0003 20.5 1.6 0.28 10.9 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF4162 PF13732.6 CDJ98460.1 - 0.00057 20.6 0.1 0.033 14.9 0.0 3.2 3 1 0 3 3 2 1 Domain of unknown function (DUF4162) MMR_HSR1 PF01926.23 CDJ98460.1 - 0.017 15.2 0.0 5 7.2 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ98460.1 - 0.02 14.8 0.3 0.4 10.6 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase SRP54 PF00448.22 CDJ98460.1 - 0.026 14.2 1.9 0.89 9.1 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 CDJ98460.1 - 0.038 14.2 0.0 16 5.8 0.0 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 CDJ98460.1 - 0.047 13.0 0.2 7.3 5.8 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin MukB PF04310.12 CDJ98460.1 - 0.063 13.1 0.8 1.5 8.5 0.1 2.3 2 0 0 2 2 2 0 MukB N-terminal AAA_15 PF13175.6 CDJ98460.1 - 0.085 12.5 0.0 11 5.6 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_13 PF13166.6 CDJ98460.1 - 0.11 11.1 0.8 1.4 7.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 CDJ98460.1 - 0.2 11.2 0.2 8.5 5.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CDJ98460.1 - 0.63 9.7 2.5 7.2 6.3 0.5 2.7 2 1 0 2 2 2 0 AAA domain Motile_Sperm PF00635.26 CDJ98461.1 - 1.1e-14 54.2 0.0 1.5e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Myb_DNA-bind_5 PF13873.6 CDJ98462.1 - 0.011 15.8 0.1 0.029 14.4 0.1 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CDJ98462.1 - 0.035 14.5 0.5 0.035 14.5 0.5 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Tho2 PF11262.8 CDJ98462.1 - 0.075 12.2 0.7 0.13 11.4 0.7 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF2353 PF09789.9 CDJ98462.1 - 0.35 10.2 7.4 0.71 9.2 0.7 2.1 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Peptidase_A17 PF05380.13 CDJ98463.1 - 1.4e-22 80.4 0.0 3.6e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 Pao retrotransposon peptidase DUF1759 PF03564.15 CDJ98463.1 - 2e-20 73.3 1.0 2e-20 73.3 1.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DUF1758 PF05585.12 CDJ98463.1 - 5.6e-15 55.5 0.1 5.2e-14 52.3 0.0 2.5 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Integrase_H2C2 PF17921.1 CDJ98463.1 - 4.1e-14 52.4 0.3 1.1e-13 51.1 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 CDJ98463.1 - 1.4e-06 28.8 0.0 1.1e-05 25.9 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 CDJ98463.1 - 1.9e-06 27.6 0.0 5.9e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CDJ98463.1 - 7.8e-06 26.4 0.0 2.4e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 CDJ98463.1 - 0.00063 19.7 0.4 0.00063 19.7 0.4 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-H2C2 PF09337.10 CDJ98463.1 - 0.0019 18.4 2.7 0.0019 18.4 2.7 2.3 3 0 0 3 3 3 1 H2C2 zinc finger RVP_2 PF08284.11 CDJ98463.1 - 0.0089 15.8 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF374 PF04028.13 CDJ98464.1 - 0.059 12.9 0.0 0.17 11.5 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF374) DUF1179 PF06678.11 CDJ98465.1 - 0.061 13.3 0.4 0.19 11.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) CAP PF00188.26 CDJ98466.1 - 6.4e-17 62.6 0.6 9.1e-17 62.1 0.6 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CDJ98467.1 - 6.8e-17 62.5 0.7 9.7e-17 62.0 0.7 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family STOP PF05217.12 CDJ98467.1 - 7.2 7.0 16.1 0.58 10.5 10.4 2.2 2 0 0 2 2 2 0 STOP protein PDZ_2 PF13180.6 CDJ98468.1 - 0.012 16.0 0.0 0.045 14.1 0.0 1.9 2 0 0 2 2 2 0 PDZ domain RRP36 PF06102.12 CDJ98469.1 - 1.5e-35 122.7 28.6 1.5e-35 122.7 28.6 3.0 2 1 1 3 3 3 1 rRNA biogenesis protein RRP36 2OG-FeII_Oxy_4 PF13661.6 CDJ98469.1 - 1.3e-23 83.5 0.1 9.6e-20 71.1 0.1 2.5 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Ofd1_CTDD PF10637.9 CDJ98469.1 - 4.4e-14 52.4 0.2 4.4e-14 52.4 0.2 4.2 3 2 0 3 3 3 1 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.6 CDJ98469.1 - 5.5e-14 52.8 0.4 7.4e-13 49.2 0.1 2.7 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily APG9 PF04109.16 CDJ98470.1 - 5.3e-142 474.2 8.4 7.1e-142 473.8 8.4 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 MMR_HSR1 PF01926.23 CDJ98471.1 - 3.2e-13 49.8 0.0 2.7e-12 46.8 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ98471.1 - 4.9e-09 35.9 0.1 4.6e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B AIG1 PF04548.16 CDJ98471.1 - 7.3e-06 25.5 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 CDJ98471.1 - 1.4e-05 25.1 0.2 0.00046 20.1 0.2 2.2 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 CDJ98471.1 - 0.00065 19.3 0.0 0.023 14.3 0.0 2.3 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Septin PF00735.18 CDJ98471.1 - 0.0024 17.2 0.0 0.0041 16.4 0.0 1.3 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.23 CDJ98471.1 - 0.012 15.7 0.6 6.9 6.7 0.1 2.9 2 1 1 3 3 3 0 Dynamin family Roc PF08477.13 CDJ98471.1 - 0.014 15.6 0.0 0.15 12.3 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 CDJ98471.1 - 0.085 12.6 0.1 1.3 8.7 0.0 2.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein IIGP PF05049.13 CDJ98471.1 - 0.11 11.5 0.1 0.29 10.2 0.0 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) TAP_C PF03943.13 CDJ98471.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 TAP C-terminal domain ABC1 PF03109.16 CDJ98472.1 - 3.7e-39 133.6 0.6 6.9e-39 132.7 0.6 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 CDJ98472.1 - 0.00061 19.2 4.3 0.053 12.9 4.3 2.3 1 1 0 1 1 1 1 Protein kinase domain Rep_Org_C PF06926.11 CDJ98472.1 - 0.063 13.6 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Putative replisome organiser protein C-terminus APH PF01636.23 CDJ98472.1 - 0.11 12.4 0.3 3.2 7.6 0.7 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-C3HC4_3 PF13920.6 CDJ98473.1 - 8.3e-08 32.0 18.0 1.3e-06 28.2 7.3 2.8 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDJ98473.1 - 2.2e-05 24.2 5.1 2.2e-05 24.2 5.1 3.1 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CDJ98473.1 - 6.7e-05 22.8 6.7 6.7e-05 22.8 6.7 2.8 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 CDJ98473.1 - 0.00013 22.2 9.2 0.00013 22.2 9.2 3.3 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 CDJ98473.1 - 0.00035 20.4 7.5 0.00035 20.4 7.5 3.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ98473.1 - 0.004 17.0 7.0 0.004 17.0 7.0 4.3 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ98473.1 - 0.024 14.7 1.9 0.024 14.7 1.9 3.1 2 1 1 3 3 3 0 RING-type zinc-finger zf-rbx1 PF12678.7 CDJ98473.1 - 0.91 9.9 14.7 0.22 11.8 9.9 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CDJ98473.1 - 1.3 9.1 10.7 0.056 13.5 4.5 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_5 PF17121.5 CDJ98473.1 - 4.6 7.2 10.0 1.3 8.9 4.8 2.7 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ion_trans_2 PF07885.16 CDJ98474.1 - 3.4e-30 103.8 17.1 4e-15 55.5 4.6 2.9 3 0 0 3 3 3 2 Ion channel Kunitz_BPTI PF00014.23 CDJ98476.1 - 5.8e-19 68.1 3.2 5.8e-19 68.1 3.2 2.2 2 0 0 2 2 2 1 Kunitz/Bovine pancreatic trypsin inhibitor domain WAP PF00095.21 CDJ98476.1 - 3.6e-08 33.7 23.5 2.9e-07 30.8 5.2 4.5 4 2 0 4 4 4 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' PC_rep PF01851.22 CDJ98477.1 - 0.01 16.2 8.1 1.8 9.1 0.1 3.8 3 0 0 3 3 3 0 Proteasome/cyclosome repeat Pkinase PF00069.25 CDJ98478.1 - 7.4e-103 343.5 0.0 7.8e-53 179.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ98478.1 - 1.7e-55 188.1 0.0 1.2e-27 96.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CDJ98478.1 - 7.3e-06 26.1 0.8 0.031 14.2 0.1 2.8 2 2 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CDJ98478.1 - 0.00013 21.4 0.0 0.11 11.8 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CDJ98478.1 - 0.00019 20.8 0.6 0.25 10.7 0.1 2.8 2 2 1 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDJ98478.1 - 0.00031 19.8 0.8 0.05 12.5 0.1 2.6 2 1 0 2 2 2 2 Haspin like kinase domain Choline_kinase PF01633.20 CDJ98478.1 - 0.0014 18.3 0.7 1.6 8.3 0.0 3.0 3 0 0 3 3 3 2 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 CDJ98478.1 - 0.002 17.3 0.0 0.84 8.6 0.0 2.4 2 0 0 2 2 2 2 Seadornavirus VP7 FTA2 PF13095.6 CDJ98478.1 - 0.0024 17.5 0.1 2 8.0 0.0 2.5 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CDJ98478.1 - 0.0035 16.2 0.1 0.37 9.5 0.1 2.2 2 0 0 2 2 2 2 Fungal protein kinase EF-hand_1 PF00036.32 CDJ98480.1 - 2.7e-14 51.6 7.2 1e-08 34.1 0.8 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDJ98480.1 - 2.7e-13 50.2 1.8 3.4e-13 49.8 1.8 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CDJ98480.1 - 2.5e-12 46.5 7.0 4.2e-10 39.3 0.6 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ98480.1 - 1.9e-11 42.9 8.1 1.5e-07 30.5 0.5 2.4 2 1 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CDJ98480.1 - 1.2e-10 40.5 5.6 1.9e-07 30.5 0.5 2.3 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CDJ98480.1 - 0.00014 22.2 0.1 0.00017 21.8 0.1 1.2 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 CDJ98480.1 - 0.0018 18.3 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0154) EF-hand_4 PF12763.7 CDJ98480.1 - 0.016 15.1 1.0 0.052 13.5 1.0 1.7 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CDJ98480.1 - 0.027 14.8 0.0 0.042 14.2 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain EF-hand_11 PF08976.11 CDJ98480.1 - 0.054 14.4 0.0 0.068 14.1 0.0 1.1 1 0 0 1 1 1 0 EF-hand domain Ets PF00178.22 CDJ98481.1 - 4.5e-36 123.2 0.2 6.8e-36 122.6 0.2 1.3 1 0 0 1 1 1 1 Ets-domain CRAL_TRIO PF00650.20 CDJ98482.1 - 7.7e-13 48.5 0.1 1.3e-12 47.8 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain NUDIX PF00293.28 CDJ98482.1 - 6.6e-10 39.1 0.0 1.5e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain CBM65_1 PF18259.1 CDJ98482.1 - 0.024 14.8 0.3 4.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Carbohydrate binding module 65 domain 1 DUF3465 PF11948.8 CDJ98482.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3465) CRAL_TRIO_2 PF13716.6 CDJ98482.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Lustrin_cystein PF14625.6 CDJ98483.1 - 0.0062 16.9 4.3 0.0062 16.9 4.3 2.5 2 0 0 2 2 2 1 Lustrin, cysteine-rich repeated domain Aminotran_3 PF00202.21 CDJ98486.1 - 3.8e-117 391.4 0.0 4.7e-117 391.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUF1794 PF08768.11 CDJ98487.1 - 2e-26 92.7 0.0 2.4e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) ShK PF01549.24 CDJ98487.1 - 0.0031 18.0 9.2 0.0048 17.4 9.2 1.3 1 0 0 1 1 1 1 ShK domain-like Arm PF00514.23 CDJ98488.1 - 4.8e-05 23.2 0.1 1.9 8.7 0.0 5.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CDJ98488.1 - 0.0052 17.1 0.1 0.45 10.9 0.0 3.3 3 1 1 4 4 4 1 HEAT repeats CDC14 PF08045.11 CDJ98488.1 - 0.036 13.2 2.3 1 8.4 0.1 2.5 2 0 0 2 2 2 0 Cell division control protein 14, SIN component HEAT PF02985.22 CDJ98488.1 - 0.14 12.5 0.0 1.3 9.5 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat ArfGap PF01412.18 CDJ98489.1 - 1.9e-40 137.6 0.0 2.9e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RVT_1 PF00078.27 CDJ98490.1 - 0.0058 16.2 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1677 PF07911.13 CDJ98490.1 - 0.12 12.8 0.4 0.22 11.9 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1677) COG5 PF10392.9 CDJ98490.1 - 0.13 12.4 2.0 0.17 12.0 0.6 1.8 1 1 1 2 2 2 0 Golgi transport complex subunit 5 FHIPEP PF00771.20 CDJ98490.1 - 0.19 10.2 0.2 0.21 10.0 0.2 1.1 1 0 0 1 1 1 0 FHIPEP family p450 PF00067.22 CDJ98491.1 - 1.1e-54 185.9 0.0 1.1e-45 156.2 0.1 2.1 1 1 1 2 2 2 2 Cytochrome P450 Asp_protease PF09668.10 CDJ98492.1 - 1.3e-17 63.7 0.4 1.8e-17 63.3 0.4 1.1 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CDJ98492.1 - 6.2e-09 35.7 0.0 7.3e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CDJ98492.1 - 1.3e-06 28.9 0.1 1.9e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ98492.1 - 0.0033 18.0 0.1 0.0051 17.4 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease DB PF01682.19 CDJ98493.1 - 5e-38 129.4 103.8 9.9e-13 48.2 13.8 6.2 5 1 1 6 6 5 4 DB module fn3 PF00041.21 CDJ98493.1 - 5.5e-31 106.8 27.0 1.2e-10 41.6 0.3 7.1 7 0 0 7 7 7 6 Fibronectin type III domain I-set PF07679.16 CDJ98493.1 - 5.7e-18 64.8 1.1 1.6e-07 31.3 0.0 4.4 5 0 0 5 5 5 2 Immunoglobulin I-set domain Ig_3 PF13927.6 CDJ98493.1 - 2.7e-14 53.5 3.1 9.8e-07 29.3 0.0 5.1 5 1 0 5 5 5 2 Immunoglobulin domain ig PF00047.25 CDJ98493.1 - 1.3e-08 34.8 0.9 0.0049 17.0 0.0 4.2 3 1 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 CDJ98493.1 - 3e-07 30.7 2.9 0.036 14.4 0.0 5.1 4 1 0 5 5 5 2 Immunoglobulin domain V-set PF07686.17 CDJ98493.1 - 0.00014 22.0 1.9 0.036 14.2 0.1 4.6 4 1 1 5 5 5 1 Immunoglobulin V-set domain Izumo-Ig PF16706.5 CDJ98493.1 - 0.0047 17.0 0.1 0.035 14.2 0.1 2.6 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain S1-like PF14444.6 CDJ98493.1 - 0.16 11.9 2.5 22 5.1 0.2 3.3 3 0 0 3 3 3 0 S1-like DUF1823 PF08853.11 CDJ98493.1 - 0.23 11.7 0.5 0.64 10.2 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1823) Interfer-bind PF09294.10 CDJ98493.1 - 0.34 11.3 13.3 1.3 9.3 0.1 5.4 6 0 0 6 6 6 0 Interferon-alpha/beta receptor, fibronectin type III Adeno_E3_CR1 PF02440.15 CDJ98493.1 - 1.2 9.0 11.8 0.031 14.0 2.4 2.9 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 RNA_pol_Rpc4 PF05132.14 CDJ98494.1 - 6.9e-12 46.0 0.4 5.5e-10 39.9 0.1 3.0 2 1 0 2 2 2 1 RNA polymerase III RPC4 EFG_II PF14492.6 CDJ98494.1 - 0.14 12.3 0.1 0.47 10.6 0.1 1.9 1 0 0 1 1 1 0 Elongation Factor G, domain II Nop52 PF05997.12 CDJ98495.1 - 1.6e-49 168.6 2.2 1.6e-49 168.6 2.2 1.8 2 0 0 2 2 2 1 Nucleolar protein,Nop52 EnY2 PF10163.9 CDJ98495.1 - 2.7e-16 59.7 3.1 8.5e-16 58.1 1.8 2.4 2 0 0 2 2 2 1 Transcription factor e(y)2 Amidohydro_1 PF01979.20 CDJ98496.1 - 6.1e-25 88.3 0.1 9.6e-25 87.6 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CDJ98496.1 - 5e-15 55.9 0.8 2.3e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family HPS3_N PF14761.6 CDJ98496.1 - 0.039 13.5 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 Amidohydro_1 PF01979.20 CDJ98497.1 - 6.2e-22 78.4 0.0 1.5e-20 73.8 0.0 2.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CDJ98497.1 - 5.6e-09 36.0 0.5 1.8e-06 27.7 0.2 2.2 2 0 0 2 2 2 2 Amidohydrolase family Ras PF00071.22 CDJ98498.1 - 5.2e-54 182.2 0.0 8.9e-54 181.5 0.0 1.4 1 0 0 1 1 1 1 Ras family UEV PF05743.13 CDJ98498.1 - 5.7e-38 129.5 0.0 1.2e-37 128.5 0.0 1.5 1 0 0 1 1 1 1 UEV domain Roc PF08477.13 CDJ98498.1 - 3.5e-21 75.6 0.0 7.5e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Vps23_core PF09454.10 CDJ98498.1 - 6.5e-12 45.2 0.3 1.5e-11 44.1 0.3 1.6 1 0 0 1 1 1 1 Vps23 core domain Arf PF00025.21 CDJ98498.1 - 2.5e-07 30.3 0.0 4.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Vps54_N PF10475.9 CDJ98498.1 - 0.0079 15.5 1.1 0.013 14.8 1.1 1.2 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Pkinase PF00069.25 CDJ98500.1 - 5.4e-66 222.6 0.0 8.1e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ98500.1 - 2.2e-29 102.5 0.0 3.5e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ98500.1 - 1.2e-07 31.3 0.0 5.5e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CDJ98500.1 - 0.00033 20.1 0.0 0.00057 19.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L32p PF01783.23 CDJ98500.1 - 0.002 18.3 0.1 0.0048 17.1 0.1 1.6 1 0 0 1 1 1 1 Ribosomal L32p protein family Pkinase_fungal PF17667.1 CDJ98500.1 - 0.0055 15.5 0.0 0.013 14.3 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase LON_substr_bdg PF02190.16 CDJ98501.1 - 7.4e-07 29.2 0.1 1e-06 28.8 0.1 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain DUF2379 PF09543.10 CDJ98501.1 - 0.027 14.7 0.2 0.044 14.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) BssS PF13991.6 CDJ98501.1 - 0.11 12.6 0.0 0.64 10.1 0.0 2.2 2 0 0 2 2 2 0 BssS protein family adh_short PF00106.25 CDJ98502.1 - 2.1e-34 118.7 1.1 2.5e-34 118.5 1.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ98502.1 - 7.9e-27 94.3 0.3 1e-26 93.9 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ98502.1 - 5.7e-05 23.1 0.6 6.7e-05 22.9 0.6 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDJ98502.1 - 0.0011 18.5 0.2 0.0015 18.0 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 CDJ98502.1 - 0.0047 16.2 0.3 0.033 13.5 0.1 2.1 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 CDJ98502.1 - 0.012 15.0 0.1 0.016 14.7 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase YtxH PF12732.7 CDJ98502.1 - 0.059 13.9 0.7 13 6.4 0.0 2.2 2 0 0 2 2 2 0 YtxH-like protein 3HCDH_N PF02737.18 CDJ98502.1 - 0.065 13.1 0.4 0.17 11.8 0.4 1.7 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.8 CDJ98502.1 - 0.11 12.3 0.3 0.19 11.5 0.3 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SNF2_N PF00176.23 CDJ98503.1 - 1.6e-52 178.4 0.1 4.8e-52 176.8 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF3535 PF12054.8 CDJ98503.1 - 6.5e-22 78.4 0.2 6.5e-22 78.4 0.2 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) Helicase_C PF00271.31 CDJ98503.1 - 2.3e-17 63.4 0.0 2e-16 60.3 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEAT PF02985.22 CDJ98503.1 - 7.6e-10 38.2 8.9 0.76 10.2 0.3 8.4 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 CDJ98503.1 - 8.2e-08 32.5 3.9 0.0035 17.7 0.1 5.3 5 1 2 7 7 7 2 HEAT repeats MA3 PF02847.17 CDJ98503.1 - 0.07 13.1 0.7 2.1 8.3 0.0 3.3 3 0 0 3 3 3 0 MA3 domain PI_PP_C PF18365.1 CDJ98503.1 - 0.12 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Phosphoinositide phosphatase C-terminal domain Spond_N PF06468.13 CDJ98504.1 - 9e-68 228.2 0.2 1.4e-67 227.6 0.2 1.3 1 0 0 1 1 1 1 Spondin_N TSP_1 PF00090.19 CDJ98504.1 - 6.3e-49 164.0 60.2 4.4e-11 42.8 3.2 6.2 5 0 0 5 5 5 5 Thrombospondin type 1 domain Reeler PF02014.16 CDJ98504.1 - 2.7e-18 67.0 0.0 7e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 Reeler domain Kunitz_BPTI PF00014.23 CDJ98504.1 - 1.9e-17 63.2 11.9 1.9e-17 63.2 11.9 3.5 3 0 0 3 3 3 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Thioredoxin_8 PF13905.6 CDJ98506.1 - 5e-30 103.7 0.0 7.3e-30 103.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 CDJ98506.1 - 2.5e-11 43.5 0.0 1e-06 28.6 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Redoxin PF08534.10 CDJ98506.1 - 5.2e-10 39.2 0.0 5.9e-10 39.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CDJ98506.1 - 1.4e-09 37.9 0.0 1.9e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 CDJ98506.1 - 1.2e-06 29.0 0.0 1.7e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CDJ98506.1 - 0.00018 21.3 0.0 0.0076 16.0 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin TraF PF13728.6 CDJ98506.1 - 0.00036 20.4 0.0 0.0015 18.4 0.0 1.8 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 CDJ98506.1 - 0.013 15.6 0.0 0.08 13.1 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_7 PF13899.6 CDJ98506.1 - 0.17 12.1 0.0 0.31 11.2 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like 7TM_GPCR_Srsx PF10320.9 CDJ98507.1 - 8.2e-13 48.3 14.9 5.6e-12 45.6 14.9 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 CDJ98507.1 - 1.4e-05 24.6 15.3 2.7e-05 23.7 15.3 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 CDJ98507.1 - 1.4e-05 24.8 6.7 1.4e-05 24.8 6.7 1.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 CDJ98507.1 - 0.0063 15.9 12.0 0.0094 15.3 12.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4199 PF13858.6 CDJ98507.1 - 3.5 8.0 14.1 0.85 10.0 0.6 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF4199) Ribos_L4_asso_C PF14374.6 CDJ98508.1 - 0.18 11.9 1.2 0.36 10.9 1.2 1.6 1 1 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain RFXA_RFXANK_bdg PF15289.6 CDJ98508.1 - 0.37 11.1 3.8 0.35 11.2 2.8 1.4 1 1 1 2 2 2 0 Regulatory factor X-associated C-terminal binding domain Transposase_1 PF01359.18 CDJ98509.1 - 7.3e-09 35.3 0.6 1.9e-08 34.0 0.6 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_26 PF13443.6 CDJ98509.1 - 0.0006 20.2 0.1 0.0013 19.1 0.1 1.6 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain CENP-B_N PF04218.13 CDJ98509.1 - 0.021 14.4 0.0 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_24 PF13412.6 CDJ98509.1 - 0.05 13.2 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 CDJ98509.1 - 0.11 12.3 0.7 0.53 10.1 0.1 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Sigma70_r3 PF04539.16 CDJ98509.1 - 0.15 12.2 0.7 4.6 7.4 0.5 2.5 2 0 0 2 2 2 0 Sigma-70 region 3 HTH_32 PF13565.6 CDJ98509.1 - 0.2 12.3 4.4 0.3 11.7 0.3 2.4 2 0 0 2 2 2 0 Homeodomain-like domain Y_phosphatase PF00102.27 CDJ98510.1 - 3.7e-69 232.9 0.2 4.8e-69 232.5 0.2 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDJ98510.1 - 6.2e-07 29.3 0.0 1.9e-06 27.7 0.1 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDJ98510.1 - 0.00032 20.7 0.2 0.0018 18.3 0.1 2.2 2 1 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CDJ98510.1 - 0.04 14.0 1.2 0.17 12.0 0.1 2.4 3 0 0 3 3 3 0 Inositol hexakisphosphate Ion_trans_2 PF07885.16 CDJ98511.1 - 8.3e-18 64.1 8.5 1.5e-17 63.4 8.5 1.4 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 CDJ98511.1 - 0.0067 15.7 3.1 0.0098 15.1 3.1 1.2 1 0 0 1 1 1 1 Ion transport protein MAS20 PF02064.15 CDJ98512.1 - 9e-38 129.3 0.0 1.2e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 MAS20 protein import receptor Collagen PF01391.18 CDJ98513.1 - 3.7e-26 90.6 109.3 3.2e-10 39.6 37.0 4.2 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 CDJ98513.1 - 0.16 12.1 0.0 0.2 11.8 0.0 1.1 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Tom6 PF17112.5 CDJ98514.1 - 0.0044 16.5 0.6 0.012 15.1 0.1 2.0 1 1 1 2 2 2 1 Mitochondrial import receptor subunit Tom6, fungal DUF3995 PF13160.6 CDJ98514.1 - 0.014 15.8 0.1 0.016 15.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) CrgA PF06781.12 CDJ98514.1 - 0.031 14.3 0.9 0.056 13.5 0.9 1.5 1 1 0 1 1 1 0 Cell division protein CrgA PIRT PF15099.6 CDJ98514.1 - 0.11 12.1 1.2 0.14 11.7 1.2 1.3 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF3040 PF11239.8 CDJ98514.1 - 0.14 12.5 6.0 0.47 10.8 6.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) TcpE PF12648.7 CDJ98514.1 - 0.24 12.0 2.0 0.34 11.5 2.0 1.2 1 0 0 1 1 1 0 TcpE family Phage_holin_3_6 PF07332.11 CDJ98514.1 - 0.31 11.1 3.9 0.48 10.5 3.9 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF443 PF04276.12 CDJ98514.1 - 0.68 9.7 5.4 1.2 8.9 2.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF443) DUF3488 PF11992.8 CDJ98516.1 - 0.36 9.7 0.9 1.8 7.4 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3488) Tyrosinase PF00264.20 CDJ98517.1 - 1.6e-35 123.4 1.2 8.8e-35 121.0 0.1 2.6 2 1 0 2 2 2 1 Common central domain of tyrosinase ShK PF01549.24 CDJ98517.1 - 7.1e-11 42.5 31.0 1.3e-08 35.2 10.3 4.3 5 0 0 5 5 5 2 ShK domain-like Kelch_1 PF01344.25 CDJ98518.1 - 7.3e-17 60.7 3.2 3.7e-07 29.6 0.0 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 CDJ98518.1 - 9.1e-13 48.0 0.4 0.0011 19.2 0.0 3.3 1 1 2 3 3 3 3 Kelch motif BTB PF00651.31 CDJ98518.1 - 1.2e-05 25.5 0.3 9.1e-05 22.7 0.0 2.0 1 1 1 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.6 CDJ98518.1 - 9.6e-05 22.6 0.0 0.0038 17.5 0.0 2.4 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_2 PF07646.15 CDJ98518.1 - 0.00091 19.1 0.5 15 5.7 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CDJ98518.1 - 0.0013 18.7 0.5 0.27 11.3 0.0 3.1 3 0 0 3 3 3 1 Galactose oxidase, central domain PQQ_3 PF13570.6 CDJ98518.1 - 0.055 14.0 0.6 2.6 8.6 0.0 2.9 3 0 0 3 3 3 0 PQQ-like domain Kelch_5 PF13854.6 CDJ98518.1 - 0.078 13.0 2.2 0.52 10.4 0.0 3.1 4 0 0 4 4 4 0 Kelch motif DUF5356 PF17309.2 CDJ98519.1 - 2.1e-41 141.1 0.0 2.5e-41 140.8 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5356) Kelch_1 PF01344.25 CDJ98520.1 - 1.9e-38 129.8 2.7 4e-13 48.7 0.1 4.4 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 CDJ98520.1 - 9.5e-29 98.7 0.7 7.2e-08 32.5 0.1 4.2 2 1 2 4 4 4 4 Kelch motif Kelch_4 PF13418.6 CDJ98520.1 - 1.6e-14 53.6 0.1 0.00025 21.0 0.0 4.1 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.15 CDJ98520.1 - 2.3e-14 52.7 3.8 5.7e-05 22.9 0.1 4.4 3 1 1 4 4 4 2 Kelch motif Kelch_3 PF13415.6 CDJ98520.1 - 3.1e-11 43.3 0.5 0.0014 18.8 0.0 4.3 4 0 0 4 4 4 3 Galactose oxidase, central domain BACK PF07707.15 CDJ98520.1 - 3.3e-07 30.4 0.2 8.5e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 CDJ98520.1 - 2.4e-06 27.4 0.2 0.086 12.9 0.0 3.2 3 0 0 3 3 3 2 Kelch motif DUF5356 PF17309.2 CDJ98521.1 - 4.1e-45 153.1 0.0 5.4e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5356) Pkinase PF00069.25 CDJ98522.1 - 2e-45 155.2 0.0 3.1e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ98522.1 - 9e-26 90.7 0.0 1.4e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ98522.1 - 6.2e-06 25.2 0.0 7.8e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDJ98522.1 - 0.06 12.7 0.0 0.99 8.7 0.0 2.1 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 CDJ98522.1 - 0.064 12.9 0.0 0.83 9.2 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PSRT PF07636.11 CDJ98522.1 - 0.067 12.9 0.3 0.15 11.8 0.3 1.6 1 0 0 1 1 1 0 PSRT RTTN_N PF14726.6 CDJ98524.1 - 0.17 12.7 2.3 0.31 11.9 0.2 2.5 1 1 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning MIX PF18529.1 CDJ98524.1 - 2.7 7.7 8.7 7.4 6.2 0.4 3.9 3 1 1 4 4 4 0 Mitochondrial membrane-anchored proteins SPT16 PF08644.11 CDJ98525.1 - 6.5 6.9 13.6 1.1 9.4 7.6 1.9 1 1 1 2 2 2 0 FACT complex subunit (SPT16/CDC68) DUF446 PF04287.12 CDJ98527.1 - 0.0055 16.7 0.1 0.015 15.3 0.1 1.7 1 0 0 1 1 1 1 tRNA pseudouridine synthase C HTH_Tnp_Tc3_2 PF01498.18 CDJ98528.1 - 1e-17 64.1 0.3 2.1e-17 63.1 0.3 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 CDJ98528.1 - 9.8e-08 31.9 0.0 2.6e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease PAX PF00292.18 CDJ98528.1 - 0.00026 20.9 0.2 0.00043 20.2 0.2 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_32 PF13565.6 CDJ98528.1 - 0.0016 19.0 0.8 0.0016 19.0 0.8 3.1 2 1 2 4 4 4 1 Homeodomain-like domain HTH_23 PF13384.6 CDJ98528.1 - 0.0085 15.9 0.1 0.0085 15.9 0.1 2.5 3 0 0 3 3 3 1 Homeodomain-like domain TrmB PF01978.19 CDJ98528.1 - 0.15 11.9 0.0 0.96 9.4 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB zf-C4 PF00105.18 CDJ98529.1 - 4.3e-28 97.6 15.5 7.3e-28 96.8 15.5 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDJ98529.1 - 3.1e-18 66.1 0.5 7.1e-18 64.9 0.0 1.8 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor E2F_CC-MB PF16421.5 CDJ98529.1 - 0.022 15.1 0.2 11 6.5 0.0 2.4 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain DUF3987 PF13148.6 CDJ98529.1 - 0.11 11.4 0.1 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) UPF0506 PF11703.8 CDJ98530.1 - 0.0039 17.5 3.9 0.004 17.5 2.9 1.5 2 0 0 2 2 2 1 UPF0506 HTH_Tnp_IS630 PF01710.16 CDJ98531.1 - 0.032 14.3 0.6 0.032 14.3 0.6 1.9 2 0 0 2 2 2 0 Transposase HTH_24 PF13412.6 CDJ98531.1 - 0.099 12.2 0.0 0.33 10.6 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding PDCD2_C PF04194.13 CDJ98531.1 - 0.49 10.5 4.6 0.17 11.9 0.2 2.2 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain FYVE_2 PF02318.16 CDJ98531.1 - 0.64 10.3 4.0 20 5.4 1.3 3.1 2 1 0 2 2 2 0 FYVE-type zinc finger HTH_32 PF13565.6 CDJ98531.1 - 1.3 9.7 6.3 0.97 10.1 0.2 3.2 3 0 0 3 3 3 0 Homeodomain-like domain Patched PF02460.18 CDJ98532.1 - 2.9e-40 138.1 18.8 3.8e-40 137.8 18.8 1.1 1 0 0 1 1 1 1 Patched family Ig_3 PF13927.6 CDJ98533.1 - 2.3e-59 198.0 0.0 1.8e-10 41.3 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 CDJ98533.1 - 1.6e-54 181.9 0.0 4e-11 42.8 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin I-set domain ig PF00047.25 CDJ98533.1 - 3.5e-38 129.6 0.0 5.3e-08 32.9 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin domain Ig_2 PF13895.6 CDJ98533.1 - 1.3e-37 127.9 0.0 4.3e-06 27.0 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin domain fn3 PF00041.21 CDJ98533.1 - 1.8e-36 124.3 13.4 4.7e-07 30.1 0.1 5.5 5 0 0 5 5 5 5 Fibronectin type III domain V-set PF07686.17 CDJ98533.1 - 1.3e-17 63.9 4.5 0.026 14.7 0.0 9.0 6 4 1 8 8 8 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDJ98533.1 - 1.1e-05 25.4 0.1 0.13 12.4 0.0 4.1 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 CDJ98533.1 - 2.2e-05 23.9 0.0 8.9 6.0 0.0 5.1 5 0 0 5 5 5 2 Immunoglobulin domain BiPBP_C PF06832.12 CDJ98533.1 - 0.00016 21.7 0.1 0.7 10.0 0.0 3.6 3 0 0 3 3 3 2 Penicillin-Binding Protein C-terminus Family Ig_C17orf99 PF17736.1 CDJ98533.1 - 0.00042 20.3 0.0 0.73 9.9 0.0 4.6 4 1 0 4 4 4 1 C17orf99 Ig domain PKD_3 PF16820.5 CDJ98533.1 - 0.0077 16.0 0.1 1.2 8.9 0.0 2.9 2 0 0 2 2 2 1 PKD-like domain C1-set PF07654.15 CDJ98533.1 - 0.025 15.0 1.6 0.47 10.9 0.0 3.9 4 1 0 4 4 4 0 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 CDJ98533.1 - 0.079 13.0 0.0 4 7.6 0.0 3.4 4 0 0 4 4 3 0 Izumo-like Immunoglobulin domain EGF_CA PF07645.15 CDJ98534.1 - 2e-65 216.8 135.8 6e-11 42.4 7.7 12.4 11 2 1 12 12 12 8 Calcium-binding EGF domain cEGF PF12662.7 CDJ98534.1 - 1.4e-47 159.2 86.1 2.8e-10 39.9 1.5 10.2 11 0 0 11 11 11 8 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CDJ98534.1 - 7.3e-22 77.4 134.1 1.6e-08 34.7 5.4 12.1 10 2 2 12 12 12 5 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 CDJ98534.1 - 4.2e-12 46.0 105.4 0.00033 20.8 8.3 11.3 9 1 1 10 10 10 7 EGF domain EGF PF00008.27 CDJ98534.1 - 5.1e-09 36.3 104.5 3.6e-05 24.0 3.9 12.0 10 1 0 10 10 10 6 EGF-like domain hEGF PF12661.7 CDJ98534.1 - 2.5e-05 24.7 93.2 0.013 16.1 1.5 13.9 13 1 0 13 13 13 4 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CDJ98534.1 - 0.0016 18.5 0.5 0.0016 18.5 0.5 9.0 8 1 1 9 9 9 4 MSP1 EGF domain 1 RRM_1 PF00076.22 CDJ98536.1 - 1.4e-10 40.9 0.1 4.6e-05 23.2 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MINDY_DUB PF04424.13 CDJ98537.1 - 2.7e-29 101.5 0.0 5.8e-29 100.5 0.0 1.6 1 0 0 1 1 1 1 MINDY deubiquitinase zf-CCCH_4 PF18044.1 CDJ98538.1 - 1.6e-16 59.7 32.3 5.4e-07 29.3 1.7 5.0 4 0 0 4 4 4 3 CCCH-type zinc finger zf-CCCH PF00642.24 CDJ98538.1 - 3.2e-14 52.4 33.5 1.2e-05 25.0 2.5 5.9 6 0 0 6 6 6 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CDJ98538.1 - 4.4e-12 46.7 19.2 0.00014 22.6 0.8 4.5 3 1 1 4 4 4 3 Torus domain zf_CCCH_4 PF18345.1 CDJ98538.1 - 6.4e-11 41.9 45.6 7.8e-06 25.8 7.2 6.2 6 1 0 6 6 6 3 Zinc finger domain zf-C3HC4 PF00097.25 CDJ98538.1 - 1.1e-05 25.2 8.3 1.1e-05 25.2 8.3 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF2013 PF09431.10 CDJ98538.1 - 4.4e-05 23.7 0.0 0.00014 22.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) zf-RING_2 PF13639.6 CDJ98538.1 - 7e-05 23.1 12.8 7e-05 23.1 12.8 3.8 3 0 0 3 3 2 1 Ring finger domain zf-CCCH_3 PF15663.5 CDJ98538.1 - 0.00013 22.2 2.7 0.00013 22.2 2.7 3.2 3 0 0 3 3 3 1 Zinc-finger containing family zf-RING_UBOX PF13445.6 CDJ98538.1 - 0.00048 20.1 4.7 0.00048 20.1 4.7 2.6 3 0 0 3 3 3 1 RING-type zinc-finger zf-CCCH_2 PF14608.6 CDJ98538.1 - 0.02 15.3 3.5 0.02 15.3 3.5 5.5 5 0 0 5 5 5 0 RNA-binding, Nab2-type zinc finger zf-RING_11 PF17123.5 CDJ98538.1 - 0.09 12.5 7.7 0.34 10.7 7.7 2.1 1 0 0 1 1 1 0 RING-like zinc finger Peptidase_S24 PF00717.23 CDJ98539.1 - 7.8e-05 22.6 0.0 0.00023 21.1 0.0 1.7 1 1 0 1 1 1 1 Peptidase S24-like # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Nematods/Haemonchus_contortus-HCON/GCA_000469685.1_HCON_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Nematods/Haemonchus_contortus-HCON/GCA_000469685.1_HCON_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Nematods/Haemonchus_contortus-HCON/GCA_000469685.1_HCON_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Nematods/Haemonchus_contortus-HCON/GCA_000469685.1_HCON_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 19:02:12 2019 # [ok]